The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VM58-1" ], "evidence": [ { "id": "R-DME-6788597", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6788597" } ] }, { "id": "R-DME-74180", "name": "HMG CoA => acetoacetic acid + acetyl CoA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [ "R-ALL-73917" ], "output_participant_list": [], "enzyme_list": [ "Q9VM58-1" ], "evidence": [ { "id": "R-DME-74180", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-74180" } ] }, { "id": "R-DME-9033235", "name": "Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q7KVJ6-1", "Q7KML2-1", "Q9W3Z3-1", "A0A0B4KHK0-1", "A1Z8D3-1", "Q9VI16-1", "E1JHE4-1", "P17336-1", "P22817-1", "B7Z0E0-1", "Q9W0M0-1", "Q9VIK0-1", "Q9VJ43-1", "Q9W5W8-1", "Q9VB02-1", "Q9VRJ4-1", "Q9W0D7-1", "Q27571-1", "Q9VM58-1", "Q9VM80-1", "Q9W106-1" ], "evidence": [ { "id": "R-DME-9033235", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9033235" } ] }, { "id": "R-DME-9033236", "name": "PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q7KVJ6-1", "Q7KML2-1", "Q9W3Z3-1", "A0A0B4KHK0-1", "A1Z8D3-1", "Q9VI16-1", "E1JHE4-1", "P17336-1", "P22817-1", "B7Z0E0-1", "Q9W0M0-1", "Q9VIK0-1", "Q9VJ43-1", "Q9W5W8-1", "Q9VB02-1", "Q9VRJ4-1", "Q9W0D7-1", "Q27571-1", "Q9VM58-1", "Q9VM80-1", "Q9W106-1" ], "evidence": [ { "id": "R-DME-9033236", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9033236" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-73917", "participant_name": "HMG CoA [mitochondrial matrix]", "crossref": [ { "id": "15467", "database": "ChEBI", "url": "" }, { "id": "C00356", "database": "COMPOUND", "url": "" }, { "id": "8143338", "database": "PubChem Substance", "url": "" }, { "id": "3040", "database": "Guide to Pharmacology - Ligands", "url": "" }, { "id": "ZINC000096014519", "database": "ZINC", "url": "" }, { "id": "HMDB0001375", "database": "HMDB Metabolite", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A0B4KHK0", "gene_name": "Gnpat", "activity": [ { "ec_number": "2.3.1.42", "activity": "dihydroxyacetone phosphate + an acyl-CoA = a 1-acylglycerone 3-phosphate + CoA.", "evidence": [ { "id": "A0A0B4KHK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK0" } ] }, { "ec_number": "2.3.1.42", "activity": "", "evidence": [ { "id": "A0A0B4KHK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK0" } ] } ] }, { "uniprot_ac": "A1Z8D3", "gene_name": "Hao", "activity": [ { "ec_number": "1.1.3.15", "activity": "glycolate + O2 = glyoxylate + H2O2.", "evidence": [ { "id": "A1Z8D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1Z8D3" } ] }, { "ec_number": "1.1.3.15", "activity": "", "evidence": [ { "id": "A1Z8D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1Z8D3" } ] } ] }, { "uniprot_ac": "B7Z0E0", "gene_name": "Idh", "activity": [ { "ec_number": "1.1.1.42", "activity": "D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH.", "evidence": [ { "id": "B7Z0E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B7Z0E0" } ] }, { "ec_number": "1.1.1.42", "activity": "", "evidence": [ { "id": "B7Z0E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B7Z0E0" } ] } ] }, { "uniprot_ac": "E1JHE4", "gene_name": "Fatp1", "activity": [ { "ec_number": "6.2.1.3", "activity": "a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "E1JHE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1JHE4" } ] }, { "ec_number": "6.2.1.3", "activity": "", "evidence": [ { "id": "E1JHE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1JHE4" } ] } ] }, { "uniprot_ac": "P17336", "gene_name": "Cat", "activity": [ { "ec_number": "1.11.1.6", "activity": "2 H2O2 = O2 + 2 H2O.", "evidence": [ { "id": "P17336", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P17336" } ] }, { "ec_number": "1.11.1.6", "activity": "", "evidence": [ { "id": "P17336", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P17336" } ] } ] }, { "uniprot_ac": "P22817", "gene_name": "Ide", "activity": [ { "ec_number": "3.4.24.56", "activity": "Degradation of insulin, glucagon and other polypeptides. No action on proteins.", "evidence": [ { "id": "P22817", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P22817" } ] }, { "ec_number": "3.4.24.56", "activity": "", "evidence": [ { "id": "P22817", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P22817" } ] } ] }, { "uniprot_ac": "Q27571", "gene_name": "Nos", "activity": [ { "ec_number": "1.14.13.39", "activity": "2 L-arginine + 3 NADPH + 4 O2 + H(+) = 2 L-citrulline + 2 nitric oxide + 3 NADP(+) + 4 H2O.", "evidence": [ { "id": "Q27571", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q27571" } ] }, { "ec_number": "1.14.13.39", "activity": "", "evidence": [ { "id": "Q27571", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q27571" } ] } ] }, { "uniprot_ac": "Q7KML2", "gene_name": "Acox1", "activity": [ { "ec_number": "1.3.3.6", "activity": "a 2,3-saturated acyl-CoA + O2 = a (2E)-enoyl-CoA + H2O2.", "evidence": [ { "id": "Q7KML2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7KML2" } ] }, { "ec_number": "1.3.3.6", "activity": "", "evidence": [ { "id": "Q7KML2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7KML2" } ] } ] }, { "uniprot_ac": "Q7KVJ6", "gene_name": "Fatp2", "activity": [ { "ec_number": "6.2.1.3", "activity": "a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "Q7KVJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7KVJ6" } ] }, { "ec_number": "6.2.1.3", "activity": "", "evidence": [ { "id": "Q7KVJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7KVJ6" } ] } ] }, { "uniprot_ac": "Q9VB02", "gene_name": "CROT", "activity": [ { "ec_number": "2.3.-.-", "activity": "", "evidence": [ { "id": "Q9VB02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VB02" } ] }, { "ec_number": "2.3.1.137", "activity": "octanoyl-CoA + (R)-carnitine = O-octanoyl-(R)-carnitine + CoA.", "evidence": [ { "id": "Q9VB02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VB02" } ] } ] }, { "uniprot_ac": "Q9VI16", "gene_name": "CRAT", "activity": [ { "ec_number": "2.3.-.-", "activity": "", "evidence": [ { "id": "Q9VI16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VI16" } ] }, { "ec_number": "2.3.1.7", "activity": "(R)-carnitine + acetyl-CoA = O-acetyl-(R)-carnitine + CoA.", "evidence": [ { "id": "Q9VI16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VI16" } ] } ] }, { "uniprot_ac": "Q9VIK0", "gene_name": "Amacr", "activity": [ { "ec_number": "5.1.99.4", "activity": "a (2S)-2-methylacyl-CoA = a (2R)-2-methylacyl-CoA.", "evidence": [ { "id": "Q9VIK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VIK0" } ] } ] }, { "uniprot_ac": "Q9VJ43", "gene_name": "ScpX", "activity": [ { "ec_number": "2.3.1.176", "activity": "4,8,12-trimethyltridecanoyl-CoA + propanoyl-CoA = 3-oxopristanoyl-CoA + CoA.", "evidence": [ { "id": "Q9VJ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJ43" } ] }, { "ec_number": "2.3.1.16", "activity": "an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA.", "evidence": [ { "id": "Q9VJ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJ43" } ] }, { "ec_number": "2.3.1.155", "activity": "tetradecanoyl-CoA + acetyl-CoA = 3-oxohexadecanoyl-CoA + CoA.", "evidence": [ { "id": "Q9VJ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJ43" } ] }, { "ec_number": "2.3.1.176", "activity": "", "evidence": [ { "id": "Q9VJ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJ43" } ] }, { "ec_number": "2.3.1.16", "activity": "", "evidence": [ { "id": "Q9VJ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJ43" } ] }, { "ec_number": "2.3.1.155", "activity": "", "evidence": [ { "id": "Q9VJ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJ43" } ] } ] }, { "uniprot_ac": "Q9VM58", "gene_name": "Hmgcl", "activity": [ { "ec_number": "4.1.3.4", "activity": "(3S)-3-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA.", "evidence": [ { "id": "Q9VM58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VM58" } ] }, { "ec_number": "4.1.3.4", "activity": "", "evidence": [ { "id": "Q9VM58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VM58" } ] } ] }, { "uniprot_ac": "Q9VM80", "gene_name": "Daao2", "activity": [ { "ec_number": "1.4.3.3", "activity": "D-lysine + O2 + H2O = 6-amino-2-oxohexanoate + H2O2 + NH4(+).", "evidence": [ { "id": "Q9VM80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VM80" } ] }, { "ec_number": "1.-.-.-", "activity": "", "evidence": [ { "id": "Q9VM80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VM80" } ] } ] }, { "uniprot_ac": "Q9VRJ4", "gene_name": "Dhrs4", "activity": [ { "ec_number": "1.-.-.-", "activity": "", "evidence": [ { "id": "Q9VRJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VRJ4" } ] }, { "ec_number": "1.1.1.184", "activity": "a secondary alcohol + NADP(+) = a ketone + NADPH + H(+).", "evidence": [ { "id": "Q9VRJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VRJ4" } ] } ] }, { "uniprot_ac": "Q9W0D7", "gene_name": "Pex10", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q9W0D7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W0D7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q9W0D7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W0D7" } ] } ] }, { "uniprot_ac": "Q9W0M0", "gene_name": "Dci", "activity": [ { "ec_number": "5.3.3.8", "activity": "a (3Z)-enoyl-CoA = a 4-saturated (2E)-enoyl-CoA.", "evidence": [ { "id": "Q9W0M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W0M0" } ] } ] }, { "uniprot_ac": "Q9W106", "gene_name": "Dmel\\CG3589", "activity": [ { "ec_number": "3.4.21.-", "activity": "", "evidence": [ { "id": "Q9W106", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W106" } ] } ] }, { "uniprot_ac": "Q9W3Z3", "gene_name": "Agxt", "activity": [ { "ec_number": "2.6.1.44", "activity": "2-oxobutanoate + L-alanine = (2S)-2-aminobutanoate + pyruvate.", "evidence": [ { "id": "Q9W3Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3Z3" } ] }, { "ec_number": "2.6.1.44", "activity": "", "evidence": [ { "id": "Q9W3Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3Z3" } ] } ] }, { "uniprot_ac": "Q9W5W8", "gene_name": "Dmel\\CG9577", "activity": [ { "ec_number": "5.3.3.21", "activity": "a (3E,5Z)-dienoyl-CoA = a (2E,4E)-(5,6-saturated)-dienoyl-CoA.", "evidence": [ { "id": "Q9W5W8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W5W8" } ] }, { "ec_number": "5.3.3.21", "activity": "", "evidence": [ { "id": "Q9W5W8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W5W8" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VM58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VM58" }, { "id": "PS50991", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50991" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Pyruvate carboxyltransferase", "eco_id": "ECO_0000259", "start_pos": 26, "end_pos": 293, "start_aa": "Val", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "4.1.3.4", "ec_name": "(3S)-3-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA.", "evidence": [ { "id": "4.1.3.4", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.3.4" }, { "id": "4.1.3.4", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=4.1.3.4" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 133, "end_pos": 135 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VM63-1", "uniprot_ac": "Q9VM63", "uniprot_id": "Q9VM63_DROME", "mass": { "chemical_mass": 26016.0, "monoisotopic_mass": 26016.0 }, "refseq": { "ac": "NP_609086", "name": "Gas41", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_609086" }, "gene_names": [ { "name": "Gas41", "type": "recommended", "evidence": [ { "id": "Q9VM63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VM63" } ] }, { "name": "CG9207", "type": "synonym", "evidence": [ { "id": "NP_609086", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_609086" }, { "id": "Q9VM63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VM63" } ] }, { "name": "Dmel\\CG9207", "type": "synonym", "evidence": [ { "id": "NP_609086", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_609086" }, { "id": "Q9VM63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VM63" } ] }, { "name": "Dmel_CG9207", "type": "synonym", "evidence": [ { "id": "Q9VM63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VM63" } ] }, { "name": "GAS41", "type": "synonym", "evidence": [ { "id": "NP_609086", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_609086" }, { "id": "Q9VM63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VM63" } ] }, { "name": "Gas41", "type": "synonym", "evidence": [ { "id": "NP_609086", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_609086" } ] }, { "name": "dGas41", "type": "synonym", "evidence": [ { "id": "NP_609086", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_609086" }, { "id": "Q9VM63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VM63" } ] } ], "protein_names": [ { "name": "YEATS domain-containing protein 4", "type": "recommended", "evidence": [ { "id": "Q9VM63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VM63/entry#names_and_taxonomy" } ] }, { "name": "CG9207-PA", "type": "synonym", "evidence": [ { "id": "NP_609086", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_609086" } ] }, { "name": "Gas41-PA", "type": "synonym", "evidence": [ { "id": "NP_609086", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_609086" } ] }, { "name": "Gas41", "type": "synonym", "evidence": [ { "id": "NP_609086", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_609086" } ] } ], "function": [ { "annotation": "Chromatin reader component of the NuA4 histone acetyltransferase (HAT) complex, a complex involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. Specifically recognizes and binds acylated histone H3, with a preference for histone H3 diacetylated at 'Lys-18' and 'Lys-27' (H3K18ac and H3K27ac) or histone H3 diacetylated at 'Lys-14' and 'Lys-27' (H3K14ac and H3K27ac). Also able to recognize and bind crotonylated histone H3. May also recognize and bind histone H3 succinylated at 'Lys-122' (H3K122succ); additional evidences are however required to confirm this result in vivo. Plays a key role in histone variant H2AZ1/H2A.Z deposition into specific chromatin regions: recognizes and binds H3K14ac and H3K27ac on the promoters of actively transcribed genes and recruits NuA4-related complex to deposit H2AZ1/H2A.Z. H2AZ1/H2A.Z deposition is required for maintenance of embryonic stem cell.", "evidence": [ { "database": "UniProtKB", "id": "Q9VM63", "url": "https://www.uniprot.org/uniprotkb/Q9VM63#function" }, { "database": "UniProtKB", "id": "ARBA00057736", "url": "https://www.uniprot.org/uniprotkb/ARBA00057736#function" } ] } ], "disease": [ { "disease_id": "DOID:3070", "recommended_name": { "id": "DOID:3070", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3070", "name": "high grade glioma", "description": "A cell type cancer that has_material_basis_in glial cells and is located in brain or located in spine." }, "synonyms": [ { "id": "DOID:3070", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3070", "name": "Neuroglial tumor", "description": "" }, { "id": "DOID:3070", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3070", "name": "glial cell tumor", "description": "" }, { "id": "DOID:3070", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3070", "name": "glioma, malignant", "description": "" }, { "id": "DOID:3070", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3070", "name": "malignant Neuroglial tumor", "description": "" }, { "id": "DOID:3070", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3070", "name": "malignant glioma", "description": "" }, { "id": "MONDO:0024498", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024498", "name": "glioma susceptibility 1", "description": "" }, { "id": "MONDO:0024498", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024498", "name": "GLM1", "description": "" }, { "id": "MONDO:0024498", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024498", "name": "glioblastoma, somatic", "description": "" }, { "id": "MONDO:0024498", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024498", "name": "glioma susceptibility 1", "description": "" }, { "id": "MONDO:0024498", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024498", "name": "glioma susceptibility 1, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0024498", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024498", "name": "glioma, susceptibility to, somatic", "description": "" }, { "id": "MIM:137800", "resource": "MIM", "url": "https://www.omim.org/entry/137800", "name": "Glioma 1", "description": "Glioma 1" } ], "unlinked_id_list": [ "DOID:0080879" ], "evidence": [ { "id": "3070", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3070" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VM63", "url": "https://www.uniprot.org/uniprotkb/Q9VM63" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Gas41", "url": "https://www.uniprot.org/uniprotkb/Q9VM63", "locus": { "chromosome": "2L", "start_pos": 6949310, "end_pos": 6950207, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0031873", "url": "https://www.ensemblgenomes.org/id/FBgn0031873" } ] } } ], "crossref": [ { "id": "FB:FBgn0031873", "url": "https://alliancegenome.org/gene/FB:FBgn0031873", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0031873", "url": "https://bgee.org/?page=gene&gene_id=FBgn0031873", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16909", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16909", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0031873", "url": "https://flybase.org/reports/FBgn0031873", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "33973", "url": "https://www.ncbi.nlm.nih.gov/gene/33973", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VM63", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VM63*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR005033", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005033", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038704", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038704", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG9207", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG9207", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VKPYHNE", "url": "https://omabrowser.org/oma/group/VKPYHNE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VM63", "url": "https://www.orthodb.org/?gene=Q9VM63", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47573", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47573", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47573:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47573:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03366", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03366", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-8866907", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8866907", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_609086", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_609086", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VM63", "url": "https://www.uniprot.org/uniprotkb/Q9VM63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VM63-1", "url": "https://www.uniprot.org/uniprotkb/Q9VM63-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTDFGGDSGGRLKGVTIVKPIVYGNIARSFGKKREEDGHTHQWKVYLKPYFNEDMSIYVKKVHFKLHESYANPNRIVVKPPYEITETGWGEFEVIIKIYFNDQSERPVTCYHILKLFQSPVVDGELSSSTTMDTKKGLVSESYEEIVFQEPTQILQHYLLLSEQSANGLLTHDTDFEEKKTKTLDNIVNVKQKVKGEIVTLKDKLKLARETISKFKAELAKVQKQPA", "length": 227, "header": "tr|Q9VM63-1|Q9VM63_DROME Isoform 1 of YEATS domain-containing protein 4 OS=Drosophila melanogaster OX=7227 GN=Gas41 PE=1 SV=2 CANONICAL=Q9VM63-1" }, "isoforms": [ { "isoform_ac": "Q9VM63-1", "url": "https://www.uniprot.org/uniprotkb/Q9VM63/entry#Q9VM63-1", "sequence": { "sequence": "MTDFGGDSGGRLKGVTIVKPIVYGNIARSFGKKREEDGHTHQWKVYLKPYFNEDMSIYVKKVHFKLHESYANPNRIVVKPPYEITETGWGEFEVIIKIYFNDQSERPVTCYHILKLFQSPVVDGELSSSTTMDTKKGLVSESYEEIVFQEPTQILQHYLLLSEQSANGLLTHDTDFEEKKTKTLDNIVNVKQKVKGEIVTLKDKLKLARETISKFKAELAKVQKQPA", "length": 227, "header": "tr|Q9VM63-1|Q9VM63_DROME Isoform 1 of YEATS domain-containing protein 4 OS=Drosophila melanogaster OX=7227 GN=Gas41 PE=1 SV=2 CANONICAL=Q9VM63-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VM63", "url": "https://www.uniprot.org/uniprotkb/Q9VM63" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VM63", "url": "https://www.uniprot.org/uniprotkb/Q9VM63" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VM63", "url": "https://www.uniprot.org/uniprotkb/Q9VM63" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VM63", "url": "https://www.uniprot.org/uniprotkb/Q9VM63" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VM63", "url": "https://www.uniprot.org/uniprotkb/Q9VM63" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VM63", "url": "https://www.uniprot.org/uniprotkb/Q9VM63" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VM63", "url": "https://www.uniprot.org/uniprotkb/Q9VM63" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VM63", "url": "https://www.uniprot.org/uniprotkb/Q9VM63" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VM63", "url": "https://www.uniprot.org/uniprotkb/Q9VM63" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VM63", "url": "https://www.uniprot.org/uniprotkb/Q9VM63" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VM63", "url": "https://www.uniprot.org/uniprotkb/Q9VM63" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG9207", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG9207", "resource": "KEGG Pathway" }, { "id": "R-DME-8866907", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8866907", "resource": "Reactome", "description": "Activation of the TFAP2 (AP-2) family of transcription factors" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZZ62-1", "protein_name": "YEATS domain-containing protein 4", "gene_name": "YEATS4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFKRMAEFGPDSGGRVKGVTIVKPIVYGNVARYFGKKREEDGHTHQWTVYVKPYRNEDMSAYVKKIQFKLHESYGNPLRVVTKPPYEITETGWGEFEIIIKIFFIDPNERPVTLYHLLKLFQSDTNAMLGKKTVVSEFYDEMIFQDPTAMMQQLLTTSRQLTLGAYKHETEFAELEVKTREKLEAAKKKTSFEIAELKERLKASRETINCLKNEIRKLEEDDQTKEI", "length": 227 }, "evidence": [ { "id": "Q9VM63", "url": "https://omabrowser.org/oma/group/Q9VM63/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O95619-1", 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"evidence": [ { "database": "UniProtKB", "id": "Q9VM63", "url": "https://www.uniprot.org/uniprotkb/Q9VM63" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "Q9VM63", "url": "https://www.uniprot.org/uniprotkb/Q9VM63" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VM63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VM63" }, { "id": "PS51037", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51037" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "YEATS", "eco_id": "ECO_0000259", "start_pos": 11, "end_pos": 162, 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VM79" } ] }, { "name": "CG17375", "type": "synonym", "evidence": [ { "id": "NP_609076", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_609076" }, { "id": "Q9VM79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VM79" } ] }, { "name": "Dmel\\CG17375", "type": "synonym", "evidence": [ { "id": "NP_609076", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_609076" } ] }, { "name": "Dmel_CG17375", "type": "synonym", "evidence": [ { "id": "Q9VM79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VM79" } ] } ], "protein_names": [ { "name": "CG17375-PB", "type": "synonym", "evidence": [ { "id": "NP_609076", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_609076" } ] }, { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "Q9VM79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VM79/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein, isoform B", "type": "synonym", "evidence": [ { "id": "NP_609076", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_609076" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VM79", "url": "https://www.uniprot.org/uniprotkb/Q9VM79" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG17375", "url": "https://www.uniprot.org/uniprotkb/Q9VM79", "locus": { "chromosome": "2L", "start_pos": 6804324, "end_pos": 6805792, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0031861", "url": "https://www.ensemblgenomes.org/id/FBgn0031861" } ] } } ], "crossref": [ { "id": "FB:FBgn0031861", "url": "https://alliancegenome.org/gene/FB:FBgn0031861", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0031861", "url": "https://bgee.org/?page=gene&gene_id=FBgn0031861", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0031861", "url": "https://flybase.org/reports/FBgn0031861", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "33956", "url": "https://www.ncbi.nlm.nih.gov/gene/33956", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VM79", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VM79*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "WPGFEAF", "url": "https://omabrowser.org/oma/group/WPGFEAF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VM79", "url": "https://www.orthodb.org/?gene=Q9VM79", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "NP_609076", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_609076", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VM79", "url": "https://www.uniprot.org/uniprotkb/Q9VM79", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VM79-1", "url": "https://www.uniprot.org/uniprotkb/Q9VM79-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEDVRTLRYDIQWDVFEGMQIVDINSKYYDMVIEFMWSNSFLKSLVYESLGLFDLPDMKQTYSWYVRHILRNECSVMMISEDETQIRAVGLLEWMTEEWHSWVFFPSSLPRNLFQQIIMMKKELIDATKANMGISTYDALFVHEIAFPDELYFNRDFLSTIFDVFGFVAQHMHMPRVSFIALSSVDQEAASLIDYEEIGRTIYSIYKVGNTRPFDILRELDEMYALLFELAVSPVLKYIEMPGFEEFHEALDARLAKEAAEKRHDDDI", "length": 268, "header": "tr|Q9VM79-1|Q9VM79_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG17375 PE=4 SV=3 CANONICAL=Q9VM79-1" }, "isoforms": [ { "isoform_ac": "Q9VM79-1", "url": "https://www.uniprot.org/uniprotkb/Q9VM79/entry#Q9VM79-1", "sequence": { "sequence": "MEDVRTLRYDIQWDVFEGMQIVDINSKYYDMVIEFMWSNSFLKSLVYESLGLFDLPDMKQTYSWYVRHILRNECSVMMISEDETQIRAVGLLEWMTEEWHSWVFFPSSLPRNLFQQIIMMKKELIDATKANMGISTYDALFVHEIAFPDELYFNRDFLSTIFDVFGFVAQHMHMPRVSFIALSSVDQEAASLIDYEEIGRTIYSIYKVGNTRPFDILRELDEMYALLFELAVSPVLKYIEMPGFEEFHEALDARLAKEAAEKRHDDDI", "length": 268, "header": "tr|Q9VM79-1|Q9VM79_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG17375 PE=4 SV=3 CANONICAL=Q9VM79-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VM79", "url": "https://www.uniprot.org/uniprotkb/Q9VM79" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VM79", "url": "https://www.uniprot.org/uniprotkb/Q9VM79" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VM79", "url": "https://www.uniprot.org/uniprotkb/Q9VM79" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VM79", "url": "https://www.uniprot.org/uniprotkb/Q9VM79" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VM79", "url": "https://www.uniprot.org/uniprotkb/Q9VM79" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VM79", "url": "https://www.uniprot.org/uniprotkb/Q9VM79" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VM79", "url": "https://www.uniprot.org/uniprotkb/Q9VM79" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VM79", "url": "https://www.uniprot.org/uniprotkb/Q9VM79" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VM79", "url": "https://www.uniprot.org/uniprotkb/Q9VM79" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VM98", "url": "https://www.uniprot.org/uniprotkb/Q9VM98" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VM98", "url": "https://www.uniprot.org/uniprotkb/Q9VM98" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VM98", "url": "https://www.uniprot.org/uniprotkb/Q9VM98" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VM98", "url": "https://www.uniprot.org/uniprotkb/Q9VM98" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VM98", "url": "https://www.uniprot.org/uniprotkb/Q9VM98" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VM98", "url": "https://www.uniprot.org/uniprotkb/Q9VM98" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VM98", "url": "https://www.uniprot.org/uniprotkb/Q9VM98" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VM98", "url": "https://www.uniprot.org/uniprotkb/Q9VM98" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VM98", "url": "https://www.uniprot.org/uniprotkb/Q9VM98" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q9VMB3", "url": "https://www.uniprot.org/uniprotkb/Q9VMB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VMB3-1", "url": "https://www.uniprot.org/uniprotkb/Q9VMB3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFSLQLQQLLRATASGVTSGATKTLCTATASAATKHSSQAKFGDNSSHGSPSHTDGRSHGESESDLESAHGQNFTSHHLARRILQQRSQDIQRHIHTQSAKGQTSAKSSQQQQHQQTATKFAMSSLAAEPLQSQKSDEITASTGGGDVETPGLGASCHEVAAASASAGKKPCFSSGLGEILQFMELIGNLKHTKRTGWVLRDVNDCESISGHMYRMSMLTFLLDGSEGLNQIRCMELALVHDLAESLVGDITPFCGISKDDKRAMEFKAMEDICKLIEPRGKRIMELFEEYEHGQTAESKFVKDLDRLDMVMQAFEYEKRDNCLLKHQEFFDSTEGKFNHPFVKKLVNEIYEQRDVLAKAKGATPPPAIEVPSMERSSKLANGHDGSS", "length": 388, "header": "tr|Q9VMB3-1|Q9VMB3_DROME Isoform 1 of 5'-deoxynucleotidase HDDC2 OS=Drosophila melanogaster OX=7227 GN=BcDNA:LD22339 PE=1 SV=1 CANONICAL=Q9VMB3-1" }, "isoforms": [ { "isoform_ac": "Q9VMB3-1", "url": "https://www.uniprot.org/uniprotkb/Q9VMB3/entry#Q9VMB3-1", "sequence": { "sequence": "MFSLQLQQLLRATASGVTSGATKTLCTATASAATKHSSQAKFGDNSSHGSPSHTDGRSHGESESDLESAHGQNFTSHHLARRILQQRSQDIQRHIHTQSAKGQTSAKSSQQQQHQQTATKFAMSSLAAEPLQSQKSDEITASTGGGDVETPGLGASCHEVAAASASAGKKPCFSSGLGEILQFMELIGNLKHTKRTGWVLRDVNDCESISGHMYRMSMLTFLLDGSEGLNQIRCMELALVHDLAESLVGDITPFCGISKDDKRAMEFKAMEDICKLIEPRGKRIMELFEEYEHGQTAESKFVKDLDRLDMVMQAFEYEKRDNCLLKHQEFFDSTEGKFNHPFVKKLVNEIYEQRDVLAKAKGATPPPAIEVPSMERSSKLANGHDGSS", "length": 388, "header": "tr|Q9VMB3-1|Q9VMB3_DROME Isoform 1 of 5'-deoxynucleotidase HDDC2 OS=Drosophila melanogaster OX=7227 GN=BcDNA:LD22339 PE=1 SV=1 CANONICAL=Q9VMB3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VMB3", "url": "https://www.uniprot.org/uniprotkb/Q9VMB3" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VMB3", "url": "https://www.uniprot.org/uniprotkb/Q9VMB3" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMB3", "url": "https://www.uniprot.org/uniprotkb/Q9VMB3" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMB3", "url": "https://www.uniprot.org/uniprotkb/Q9VMB3" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VMB3", "url": "https://www.uniprot.org/uniprotkb/Q9VMB3" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VMB3", "url": "https://www.uniprot.org/uniprotkb/Q9VMB3" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VMB3", "url": "https://www.uniprot.org/uniprotkb/Q9VMB3" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMB3", "url": "https://www.uniprot.org/uniprotkb/Q9VMB3" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMB3", "url": "https://www.uniprot.org/uniprotkb/Q9VMB3" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VMB3", "url": "https://www.uniprot.org/uniprotkb/Q9VMB3" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VMB3", "url": "https://www.uniprot.org/uniprotkb/Q9VMB3" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG11050", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG11050", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LVN3-1", "protein_name": "5'-deoxynucleotidase HDDC2", "gene_name": "Hddc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASATSNCQAGLLRFLRLVGQLKRVPRTGWVYRNVEKPESVSDHMYRMAVMAMVTRDDRLNKDRCIRLALVHDMAECIVGDIAPADNIPKEEKHRREEEAMKEITQLLPEDLRKELYELWEEYETQSSEEARFVKQLDQCEMILQASEYEDMENKPGRLQDFYDSTAAGGERKKWWGENVRACEKHISKDWDASAK", "length": 196 }, "evidence": [ { "id": "RGD:1307562", "url": "https://alliancegenome.org/gene/RGD:1307562#orthology", "database": "AGR" }, { "id": "MGI:1916942", "url": "https://alliancegenome.org/gene/MGI:1916942#orthology", "database": "AGR" }, { "id": "HGNC:21078", "url": "https://alliancegenome.org/gene/HGNC:21078#orthology", "database": "AGR" }, { "id": "FB:FBgn0031836", "url": "https://alliancegenome.org/gene/FB:FBgn0031836#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050522-394", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-394#orthology", "database": "AGR" }, { "id": "SGD:S000003069", "url": "https://alliancegenome.org/gene/SGD:S000003069#orthology", "database": "AGR" }, { "id": "SGD:S000000446", "url": "https://alliancegenome.org/gene/SGD:S000000446#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P38331-1", "protein_name": "5'-deoxynucleotidase YBR242W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTATITNKKSCSGSVEAGKTRLTTEWKPESQVPQYVKNELSKPHPNYILAFLNVVQQLKIQRRTGYLDLGIKECESISDHMYRLSIITMLIKDSRVNRDKCVRIALVHDIAESLVGDITPVDPIGKEEKHRREWETIKYLCNALIKPYNEIAAKEIMDDWLAYENVTSLEARYVKDIDKYEMLVQCFEYEREYKGTKNFDDFFGAVASIKTDEVKGWTSDLVVQRQKYFADLTQSITK", "length": 238 }, "evidence": [ { "id": "RGD:1307562", "url": "https://alliancegenome.org/gene/RGD:1307562#orthology", "database": "AGR" }, { "id": "MGI:1916942", "url": "https://alliancegenome.org/gene/MGI:1916942#orthology", "database": "AGR" }, { "id": "HGNC:21078", "url": "https://alliancegenome.org/gene/HGNC:21078#orthology", "database": "AGR" }, { "id": "FB:FBgn0031836", "url": "https://alliancegenome.org/gene/FB:FBgn0031836#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050522-394", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-394#orthology", "database": "AGR" }, { "id": "SGD:S000000446", "url": "https://alliancegenome.org/gene/SGD:S000000446#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P53144-1", "protein_name": "5'-deoxynucleotidase YGK1", "gene_name": "YGK1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTAVNIWKPEDNIPREILAILSKPHPNYQLAFLNIIQLLKTQRRTGWVDHGIDPCESISDHMYRMGLTTMLITDKNVDRNKCIRIALVHDFAESLVGDITPNDPMTKEEKHRREFETVKYLCESIIRPCSESASREILDDWLAYEKQTCLEGRYVKDIDKYEMLVQCFEYEQKYNGKKDLKQFLGAINDIKTDEVKKWTQSLLEDRQAFFDSLKE", "length": 215 }, "evidence": [ { "id": "RGD:1307562", "url": "https://alliancegenome.org/gene/RGD:1307562#orthology", "database": "AGR" }, { "id": "MGI:1916942", "url": "https://alliancegenome.org/gene/MGI:1916942#orthology", "database": "AGR" }, { "id": "HGNC:21078", "url": "https://alliancegenome.org/gene/HGNC:21078#orthology", "database": "AGR" }, { "id": "FB:FBgn0031836", "url": "https://alliancegenome.org/gene/FB:FBgn0031836#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050522-394", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-394#orthology", "database": "AGR" }, { "id": "SGD:S000003069", "url": "https://alliancegenome.org/gene/SGD:S000003069#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q1LUI2-1", "protein_name": "5'-deoxynucleotidase HDDC2", "gene_name": "hddc2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDNMLQFMKLVGQLKRVPRTGWVYRNIKQPESVSDHMYRMSMMALTIQDISVNKERCMKLALVHDLAECIVGDIAPADNVSKAEKHRREKDAMVHITGLLDDGLRKEIYNLWEEYETQSSPEAKLVKELDNLEMIIQAHEYEELEGKPGRLQEFFVSTEGKFHHPEVLGLLKSLNEERARHIAAGGEKTTDTDSLTLAKP", "length": 200 }, "evidence": [ { "id": "RGD:1307562", "url": "https://alliancegenome.org/gene/RGD:1307562#orthology", "database": "AGR" }, { "id": "MGI:1916942", "url": "https://alliancegenome.org/gene/MGI:1916942#orthology", "database": "AGR" }, { "id": "HGNC:21078", "url": "https://alliancegenome.org/gene/HGNC:21078#orthology", "database": "AGR" }, { "id": "FB:FBgn0031836", "url": "https://alliancegenome.org/gene/FB:FBgn0031836#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050522-394", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-394#orthology", "database": "AGR" }, { "id": "SGD:S000003069", "url": "https://alliancegenome.org/gene/SGD:S000003069#orthology", "database": "AGR" }, { "id": "SGD:S000000446", "url": "https://alliancegenome.org/gene/SGD:S000000446#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q3SXD3-1", "protein_name": "5'-deoxynucleotidase HDDC2", "gene_name": "Hddc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALASSGSGAGLLRFLRLVGQLKRVPRTGWVYRNVEKPESVSDHMYRMAVMAMVTRDDRLNKDRCIRLALVHDMAECIVGDIAPADNIPKEEKHRREEEAMKQITQLLPEDLRKELYELWEEYETQSSEEAKFVKQLDQCEMILQASEYEDLENKPGRLQDFYDSTAGKFSHPEIVQLVSELETERNASMATASAEPGS", "length": 199 }, "evidence": [ { "id": "RGD:1307562", "url": "https://alliancegenome.org/gene/RGD:1307562#orthology", "database": "AGR" }, { "id": "MGI:1916942", "url": "https://alliancegenome.org/gene/MGI:1916942#orthology", "database": "AGR" }, { "id": "HGNC:21078", "url": "https://alliancegenome.org/gene/HGNC:21078#orthology", "database": "AGR" }, { "id": "FB:FBgn0031836", "url": "https://alliancegenome.org/gene/FB:FBgn0031836#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050522-394", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-394#orthology", "database": "AGR" }, { "id": "SGD:S000003069", "url": "https://alliancegenome.org/gene/SGD:S000003069#orthology", "database": "AGR" }, { "id": "SGD:S000000446", "url": "https://alliancegenome.org/gene/SGD:S000000446#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7Z4H3-1", "protein_name": "5'-deoxynucleotidase HDDC2", "gene_name": "HDDC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASVSSATFSGHGARSLLQFLRLVGQLKRVPRTGWVYRNVQRPESVSDHMYRMAVMAMVIKDDRLNKDRCVRLALVHDMAECIVGDIAPADNIPKEEKHRREEEAMKQITQLLPEDLRKELYELWEEYETQSSAEAKFVKQLDQCEMILQASEYEDLEHKPGRLQDFYDSTAGKFNHPEIVQLVSELEAERSTNIAAAASEPHS", "length": 204 }, "evidence": [ { "id": "RGD:1307562", "url": "https://alliancegenome.org/gene/RGD:1307562#orthology", "database": "AGR" }, { "id": "MGI:1916942", "url": "https://alliancegenome.org/gene/MGI:1916942#orthology", "database": "AGR" }, { "id": "HGNC:21078", "url": "https://alliancegenome.org/gene/HGNC:21078#orthology", "database": "AGR" }, { "id": "FB:FBgn0031836", "url": "https://alliancegenome.org/gene/FB:FBgn0031836#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050522-394", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-394#orthology", "database": "AGR" }, { "id": "SGD:S000003069", "url": "https://alliancegenome.org/gene/SGD:S000003069#orthology", "database": "AGR" }, { "id": "SGD:S000000446", "url": "https://alliancegenome.org/gene/SGD:S000000446#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": 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KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei 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"title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VMB5", "url": "https://www.uniprot.org/uniprotkb/Q9VMB5" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMB5", "url": "https://www.uniprot.org/uniprotkb/Q9VMB5" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMB5", "url": "https://www.uniprot.org/uniprotkb/Q9VMB5" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VMB5", "url": "https://www.uniprot.org/uniprotkb/Q9VMB5" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VMB5", "url": "https://www.uniprot.org/uniprotkb/Q9VMB5" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VMB5", "url": "https://www.uniprot.org/uniprotkb/Q9VMB5" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi 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Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VMB9", "url": "https://www.uniprot.org/uniprotkb/Q9VMB9" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VMB9", "url": "https://www.uniprot.org/uniprotkb/Q9VMB9" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMB9", "url": "https://www.uniprot.org/uniprotkb/Q9VMB9" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMB9", "url": "https://www.uniprot.org/uniprotkb/Q9VMB9" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VMB9", "url": "https://www.uniprot.org/uniprotkb/Q9VMB9" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VMB9", "url": "https://www.uniprot.org/uniprotkb/Q9VMB9" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VMB9", "url": "https://www.uniprot.org/uniprotkb/Q9VMB9" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMB9", "url": "https://www.uniprot.org/uniprotkb/Q9VMB9" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMB9", "url": "https://www.uniprot.org/uniprotkb/Q9VMB9" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VMB9", "url": "https://www.uniprot.org/uniprotkb/Q9VMB9" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VMB9", "url": "https://www.uniprot.org/uniprotkb/Q9VMB9" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG11015", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG11015", "resource": "KEGG Pathway" }, { "id": "R-DME-5628897", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-5628897", "resource": "Reactome", "description": "TP53 Regulates Metabolic Genes" }, { "id": "R-DME-611105", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-611105", "resource": "Reactome", "description": "Respiratory electron transport" }, { "id": "R-DME-9707564", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9707564", "resource": "Reactome", "description": "Cytoprotection by HMOX1" }, { "id": "R-DME-9837999", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9837999", "resource": "Reactome", "description": "Mitochondrial protein degradation" }, { "id": "R-DME-9864848", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9864848", "resource": "Reactome", "description": "Complex IV assembly" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AB13A3X0-1", "protein_name": "Cytochrome c oxidase subunit 5B, mitochondrial", "gene_name": "cox5bb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAARLLLRSATRAVVLRHRTLPAPAVARALASGGIPTDDEQATGLERIVMEASKKGLDPYNILKPKEYAGSKQDPHIVPSISTKRIVGCVCEEDNTAVVWFWLHQGEAQRCPSCGAYYKLVPHELPH", "length": 127 }, "evidence": [ { "id": "RGD:620608", "url": "https://alliancegenome.org/gene/RGD:620608#orthology", "database": "AGR" }, { "id": "MGI:88475", "url": "https://alliancegenome.org/gene/MGI:88475#orthology", "database": "AGR" }, { "id": "HGNC:2269", "url": "https://alliancegenome.org/gene/HGNC:2269#orthology", "database": "AGR" }, { "id": "FB:FBgn0031830", "url": "https://alliancegenome.org/gene/FB:FBgn0031830#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100525-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100525-2#orthology", "database": "AGR" }, { "id": "SGD:S000003155", "url": "https://alliancegenome.org/gene/SGD:S000003155#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P04037-1", "protein_name": "Cytochrome c oxidase subunit 4, mitochondrial", "gene_name": "COX4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLSLRQSIRFFKPATRTLCSSRYLLQQKPVVKTAQNLAEVNGPETLIGPGAKEGTVPTDLDQETGLARLELLGKLEGIDVFDTKPLDSSRKGTMKDPIIIESYDDYRYVGCTGSPAGSHTIMWLKPTVNEVARCWECGSVYKLNPVGVPNDDHHH", "length": 155 }, "evidence": [ { "id": "RGD:620608", "url": "https://alliancegenome.org/gene/RGD:620608#orthology", "database": "AGR" }, { "id": "MGI:88475", "url": "https://alliancegenome.org/gene/MGI:88475#orthology", "database": "AGR" }, { "id": "HGNC:2269", "url": "https://alliancegenome.org/gene/HGNC:2269#orthology", "database": "AGR" }, { "id": "FB:FBgn0031830", "url": "https://alliancegenome.org/gene/FB:FBgn0031830#orthology", "database": "AGR" }, { "id": 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"url": "https://alliancegenome.org/gene/FB:FBgn0031830#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100525-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100525-2#orthology", "database": "AGR" }, { "id": "SGD:S000003155", "url": "https://alliancegenome.org/gene/SGD:S000003155#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P12075-1", "protein_name": "Cytochrome c oxidase subunit 5B, mitochondrial", "gene_name": "Cox5b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASRLLRGVGALAAQALRAHGPRGVAATRSMASGGGVPTDEEQATGLEREIMIAAQRGLDPYNMLPPKAASGTKEDPNLVPSVSNKRIVGCICEEDNCTVIWFWLHQGESQRCPNCGTHYKLVPYQMVH", "length": 129 }, "evidence": [ { "id": "RGD:620608", "url": "https://alliancegenome.org/gene/RGD:620608#orthology", "database": "AGR" }, { "id": "MGI:88475", "url": "https://alliancegenome.org/gene/MGI:88475#orthology", "database": "AGR" }, { "id": "HGNC:2269", "url": "https://alliancegenome.org/gene/HGNC:2269#orthology", "database": "AGR" }, { "id": "FB:FBgn0031830", "url": "https://alliancegenome.org/gene/FB:FBgn0031830#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100525-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100525-2#orthology", "database": "AGR" }, { "id": "SGD:S000003155", "url": "https://alliancegenome.org/gene/SGD:S000003155#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P19536-1", "protein_name": "Cytochrome c oxidase subunit 5B, mitochondrial", "gene_name": "Cox5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASRLLRGVGALAAQALRRTARGAAVTRSMASGGGVPTDEEQATGLEREIMIAAQKGLDPYNMLPPKAASGTKEDPNLVPSISNKRIVGCICEEDNCTVIWFWLHKGESQRCPNCGTHYKLVPHQMAH", "length": 128 }, "evidence": [ { "id": "RGD:620608", "url": "https://alliancegenome.org/gene/RGD:620608#orthology", "database": "AGR" }, { "id": "MGI:88475", "url": 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"url": "https://alliancegenome.org/gene/RGD:620608#orthology", "database": "AGR" }, { "id": "MGI:88475", "url": "https://alliancegenome.org/gene/MGI:88475#orthology", "database": "AGR" }, { "id": "HGNC:2269", "url": "https://alliancegenome.org/gene/HGNC:2269#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100525-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100525-2#orthology", "database": "AGR" }, { "id": "SGD:S000003155", "url": "https://alliancegenome.org/gene/SGD:S000003155#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9VMB9", "url": "https://www.uniprot.org/uniprotkb/Q9VMB9" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13906:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03062", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03062", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q9VMD5", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q9VMD5", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-DME-1482922", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1482922", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_609029", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_609029", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "12937", "url": "https://www.rhea-db.org/rhea/12937", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "32995", "url": "https://www.rhea-db.org/rhea/32995", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "33191", "url": "https://www.rhea-db.org/rhea/33191", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "37015", "url": "https://www.rhea-db.org/rhea/37015", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "37207", "url": "https://www.rhea-db.org/rhea/37207", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "37399", "url": "https://www.rhea-db.org/rhea/37399", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "37419", "url": "https://www.rhea-db.org/rhea/37419", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q9VMD5", "url": "https://www.uniprot.org/uniprotkb/Q9VMD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VMD5-1", "url": "https://www.uniprot.org/uniprotkb/Q9VMD5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSIDDVIYVICLLGCIGAGSYVKKIADEGQRKLVSTGLGVLVVVIVSGLHSLHCFVSLALGTAAVLLVHPSKGHLVTFAVMFGYLVFFRIFDFYFGIPGHTNMIQMILTLKVSGIAFEKTAAWKRLQAHDEQKKNDQRDVHQESPIEITDYDVELQSLSAAEILHYSFNYIGVLTGPYYRYRTYRDYFEMPFKTYAPTVEATLEKLKYAVFYCALYLATNYMWPLDYALSDEFFNDRSFVYRLLYVWPTFFTFRARIYTGLTLSECVCTMAGFGAYPDESDPNNGEGPRKRYQHLKRDADKHTYNFTTIVNTRVLEVERCWTFREGMKHWNVCVQYWLAVNVYKLFPSKKYRTGATLLCSAYWHGFRPGHYFCIMGAPFYVSLEDMWDKLVRKSATGTSRRVIDVIFWIFKWFAFSYLGEAFLLSSFGNIWRFYSSVYHIGYISWAAMTALGFYLTSQRKAAERRKKRAAEKAAGGDGIAAAIEKEKAQ", "length": 489, "header": "sp|Q9VMD5-1|MBOA7_DROME Isoform 1 of Membrane-bound acylglycerophosphatidylinositol O-acyltransferase frj OS=Drosophila melanogaster OX=7227 GN=frj PE=1 SV=1 CANONICAL=Q9VMD5-1" }, "isoforms": [ { "isoform_ac": "Q9VMD5-1", "url": "https://www.uniprot.org/uniprotkb/Q9VMD5/entry#Q9VMD5-1", "sequence": { "sequence": "MSIDDVIYVICLLGCIGAGSYVKKIADEGQRKLVSTGLGVLVVVIVSGLHSLHCFVSLALGTAAVLLVHPSKGHLVTFAVMFGYLVFFRIFDFYFGIPGHTNMIQMILTLKVSGIAFEKTAAWKRLQAHDEQKKNDQRDVHQESPIEITDYDVELQSLSAAEILHYSFNYIGVLTGPYYRYRTYRDYFEMPFKTYAPTVEATLEKLKYAVFYCALYLATNYMWPLDYALSDEFFNDRSFVYRLLYVWPTFFTFRARIYTGLTLSECVCTMAGFGAYPDESDPNNGEGPRKRYQHLKRDADKHTYNFTTIVNTRVLEVERCWTFREGMKHWNVCVQYWLAVNVYKLFPSKKYRTGATLLCSAYWHGFRPGHYFCIMGAPFYVSLEDMWDKLVRKSATGTSRRVIDVIFWIFKWFAFSYLGEAFLLSSFGNIWRFYSSVYHIGYISWAAMTALGFYLTSQRKAAERRKKRAAEKAAGGDGIAAAIEKEKAQ", "length": 489, "header": "sp|Q9VMD5-1|MBOA7_DROME Isoform 1 of Membrane-bound acylglycerophosphatidylinositol O-acyltransferase frj OS=Drosophila melanogaster OX=7227 GN=frj PE=1 SV=1 CANONICAL=Q9VMD5-1" }, "locus": { "chromosome": "2L", "start_pos": 6456267, "end_pos": 6459008, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0079258", "url": "https://www.ensemblgenomes.org/id/FBtr0079258" }, { "database": "Ensembl Peptide", "id": "FBpp0078888", "url": "https://www.ensemblgenomes.org/id/FBpp0078888" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VMD5", "url": "https://www.uniprot.org/uniprotkb/Q9VMD5" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMD5", "url": "https://www.uniprot.org/uniprotkb/Q9VMD5" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "Drosophila lysophospholipid acyltransferases are specifically required for germ cell development.", "journal": "Molecular biology of the cell", "date": "2009-12", "authors": "Steinhauer Josefa, Gij\u00f3n Miguel A, Riekhof Wayne R, Voelker Dennis R, Murphy Robert C, Treisman Jessica E", "evidence": [ { "database": "UniProtKB", "id": "Q9VMD5", "url": "https://www.uniprot.org/uniprotkb/Q9VMD5" } ], "reference": [ { "type": "PubMed", "id": "19864461", "url": "https://glygen.org/publication/PubMed/19864461" } ] } ], "pathway": [ { "id": "dme:Dmel_CG9526", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG9526", "resource": "KEGG Pathway" }, { "id": "R-DME-1482922", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1482922", "resource": "Reactome", "description": "Acyl chain remodelling of PI" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RNH0-1", "protein_name": "Leukocyte receptor cluster member 4", "gene_name": "MBOAT7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSPEEWTYLVVLLISIPIGFLFKKAGPGLKRWGAAAVGLGLTLFTCGPHTLHSLITILGTWALIQAQPCSCHALALAWTFSYLLFFRALSLLGLPTPTPFTNAVQLLLTLKLVSLASEVQDLHMAQRKEMASGFVKGPSLGLLPEVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPFPGAVPSLRPLLRRAWPAPLFGLLFLLSSHIFPLEAVREDAFYARPLPARLFYMIPVFFAFRMRFYVAWIAAECGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSPEKAASLEYDYETVRNIDCYGTDFCVRVRDGMRYWNMTVQWWLAQYIYKSAPTRSYVLRSAWTMLLSAYWHGLHPGYYLSFLTIPLCLAAEGCLESALRGRLSPGGQKAWDWVHWFLKMRAYDYMCMGFVLLSLGDTLRYWASIYFCIHILALGALGLGLALGGGSPSRRKAATPTPSLASGKLREE", "length": 472 }, "evidence": [ { "id": "Q9VMD5", "url": "https://omabrowser.org/oma/group/Q9VMD5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3V7N6-1", "protein_name": "Leukocyte receptor cluster member 4", "gene_name": "Mboat7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTPEEWTYLMVLLISIPVGFLFKKAGPGLKRWGAAAVGLGLTLFTCGPHSLHSLITILGTWALIQAQPCSCHALALAWTFSYLLFFRALSLLGLPTPTPFTNAVQLLLTLKLVSLASEVQDLHLAQRKEMASGFSKEPTLGLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPFPEAVPSLRPLLRRAWPAPLFGLLFLLSSHLFPLEAVREDAFYARPLPTRLFYMIPVFFAFRMRFYVAWIAAECGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSPEIAASLEYDYEAIRNIDCYGTDFCVRVRDGMRYWNMTVQWWLAQYIYKSAPFRSYVLRSAWTMLLSAYWHGLHPGYYLSFMTIPLCLAAEGYLESALRRHLSPGGQKAWDWFHWFLKMRAYDYMCMGFVLLSMGDTLRYWASIYFWVHFLALACLGLGLALGGGSPSKRKTPSQATTSQAKEKLREE", "length": 473 }, "evidence": [ { "id": "RGD:1306945", "url": "https://alliancegenome.org/gene/RGD:1306945#orthology", "database": "AGR" }, { "id": "HGNC:15505", "url": "https://alliancegenome.org/gene/HGNC:15505#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1516", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1516#orthology", "database": "AGR" }, { "id": "MGI:1924832", "url": "https://alliancegenome.org/gene/MGI:1924832#orthology", "database": "AGR" }, { "id": "FB:FBgn0031815", "url": "https://alliancegenome.org/gene/FB:FBgn0031815#orthology", "database": "AGR" }, { "id": "Q9VMD5", "url": "https://omabrowser.org/oma/group/Q9VMD5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q0VCY6-1", "protein_name": "Membrane-bound acylglycerophosphatidylinositol O-acyltransferase MBOAT7", "gene_name": "MBOAT7", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSPEEWTYLVVLLISIPIGFLFKKAGPGLKRWGAAAVGLGLTLFTCGPHTLHSLVTILGTWALIQAQPCSCHALALAWTFSYLLFFRALSLLGLPTPTPFTNAVQLLLTLKLVSLASEVQDLHVAQRKEMASGFSKGPPLGLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPFPGAVPSLRPLLRRAWPAPLFGLLFLLSSHLFPLEAVREDAFYARPLPARLFYMIPVFFAFRMRFYVAWIAAECGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSPEMAASLEYDYETIRNIDCYNTDFCVTVREGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHPGYYLSFLTIPLCLAAERQLESALRWRLGPGGQKAWDWVHWFLKMRAYDYMSMGFVLLSLRDTLRYWASVYFCVHVLALAALGLGLALGRGGPGRRKSGAPAPSPASGKLREE", "length": 472 }, "evidence": [ { "id": "Q9VMD5", "url": "https://omabrowser.org/oma/group/Q9VMD5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q7SZQ0-1", "protein_name": "Membrane-bound acylglycerophosphatidylinositol O-acyltransferase mboat7", "gene_name": "mboat7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSPDELVYLGILAATIPVGFLFRYLSPPVKQGAALLLGLIISIATCGIHTLHSLCTVLGTWIIIKINWRSAPALSLAWTFLYLLFFRLVTWFGLPQPTPFANAIQLLLTLKMVSLANEVQSYHLERKKEVSTFTKSPVVAGLSHEPSLYDIISYSYCYVGIMTGPFFRYQTYADWLQQSSPLSLPGKEPCLQRLKMVPVYGLLFIAVNSVFPLSYVRTEDFLEHNYFYRFFYMVAIFFVFRMRFYSAWCGAEAGCISAGLGCYPQGALSKPGGGPTVKYSPDPETAVEYDFKTIQNIDCYNTDFCVKVRHGMRYWNMTVQWWLHHYIYPNAPFRAYALRAGWTMLISAYWHGLHAGYYLSFLTIPLCIAAETAMEASVRARLGPAGQNIFDWIHWFLKMRAYDYMCMGFVLLKASDTISYWSSIYFVIHIIAIVCIAVGQFMKGGRKREKRERGEGEKEDAVREKAE", "length": 467 }, "evidence": [ { "id": "RGD:1306945", "url": "https://alliancegenome.org/gene/RGD:1306945#orthology", "database": "AGR" }, { "id": "HGNC:15505", "url": "https://alliancegenome.org/gene/HGNC:15505#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1516", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1516#orthology", "database": "AGR" }, { "id": "MGI:1924832", "url": "https://alliancegenome.org/gene/MGI:1924832#orthology", "database": "AGR" }, { "id": "FB:FBgn0031815", "url": "https://alliancegenome.org/gene/FB:FBgn0031815#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8CHK3-1", "protein_name": "Membrane-bound acylglycerophosphatidylinositol O-acyltransferase MBOAT7", "gene_name": "Mboat7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTPEEWTYLMVLLISIPVGFLFKKAGPGLKRWGAAAVGLGLTLFTCGPHSLHSLITILGTWALIQAQPCSCHALALAWTFSYLLFFRALSLLGLPTPTPFTNAVQLLLTLKLVSLASEVQDLHLAQRKEIASGFHKEPTLGLLPEVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPFPEAVPSLRPLLRRAWPAPLFGLLFLLSSHLFPLEAVREDAFYARPLPTRLFYMIPVFFAFRMRFYVAWIAAECGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSPEIAASLEYDYETIRNIDCYGTDFCVRVRDGMRYWNMTVQWWLAQYIYKSAPFRSYVLRSAWTMLLSAYWHGLHPGYYLSFMTIPLCLAAEGYLESALRRHLSPGGQKAWDWVHWFLKMRAYDYMCMGFVLLSMADTLRYWASIYFWVHFLALACLGLGLVLGGGSPSKRKTPSQATSSQAKEKLREE", "length": 473 }, "evidence": [ { "id": "RGD:1306945", "url": "https://alliancegenome.org/gene/RGD:1306945#orthology", "database": "AGR" }, { "id": "HGNC:15505", "url": "https://alliancegenome.org/gene/HGNC:15505#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1516", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1516#orthology", "database": "AGR" }, { "id": "MGI:1924832", "url": "https://alliancegenome.org/gene/MGI:1924832#orthology", "database": "AGR" }, { "id": "FB:FBgn0031815", "url": "https://alliancegenome.org/gene/FB:FBgn0031815#orthology", "database": "AGR" }, { "id": "Q9VMD5", "url": "https://omabrowser.org/oma/group/Q9VMD5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96N66-1", "protein_name": "Membrane-bound acylglycerophosphatidylinositol O-acyltransferase MBOAT7", "gene_name": "MBOAT7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSPEEWTYLVVLLISIPIGFLFKKAGPGLKRWGAAAVGLGLTLFTCGPHTLHSLVTILGTWALIQAQPCSCHALALAWTFSYLLFFRALSLLGLPTPTPFTNAVQLLLTLKLVSLASEVQDLHLAQRKEMASGFSKGPTLGLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPFPGAVPSLRPLLRRAWPAPLFGLLFLLSSHLFPLEAVREDAFYARPLPARLFYMIPVFFAFRMRFYVAWIAAECGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYSTDFCVRVRDGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHPGYYLSFLTIPLCLAAEGRLESALRGRLSPGGQKAWDWVHWFLKMRAYDYMCMGFVLLSLADTLRYWASIYFCIHFLALAALGLGLALGGGSPSRRKAASQPTSLAPEKLREE", "length": 472 }, "evidence": [ { "id": "RGD:1306945", "url": "https://alliancegenome.org/gene/RGD:1306945#orthology", "database": "AGR" }, { "id": "HGNC:15505", "url": "https://alliancegenome.org/gene/HGNC:15505#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1516", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1516#orthology", "database": "AGR" }, { "id": "MGI:1924832", "url": "https://alliancegenome.org/gene/MGI:1924832#orthology", "database": "AGR" }, { "id": "FB:FBgn0031815", "url": "https://alliancegenome.org/gene/FB:FBgn0031815#orthology", "database": "AGR" }, { "id": "Q9VMD5", "url": "https://omabrowser.org/oma/group/Q9VMD5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VMD5", "url": "https://www.uniprot.org/uniprotkb/Q9VMD5" } ], "pmid": "" }, { "name": "mitochondria-associated endoplasmic reticulum membrane contact site", "id": "GO:0044233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044233", "evidence": [ { "database": "UniProtKB", "id": "Q9VMD5", "url": "https://www.uniprot.org/uniprotkb/Q9VMD5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "phosphatidylinositol biosynthetic process", "id": "GO:0006661", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006661", "evidence": [ { "database": "UniProtKB", "id": "Q9VMD5", "url": "https://www.uniprot.org/uniprotkb/Q9VMD5" } ], "pmid": "" }, { "name": "lipid modification", "id": "GO:0030258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030258", "evidence": [ { "database": "UniProtKB", "id": "Q9VMD5", "url": "https://www.uniprot.org/uniprotkb/Q9VMD5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "1-acylglycerophosphocholine O-acyltransferase activity", "id": "GO:0047184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047184", "evidence": [ { "database": "UniProtKB", "id": "Q9VMD5", "url": "https://www.uniprot.org/uniprotkb/Q9VMD5" } ], "pmid": "" }, { "name": "lysophospholipid acyltransferase activity", "id": "GO:0071617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071617", "evidence": [ { "database": "UniProtKB", "id": "Q9VMD5", "url": "https://www.uniprot.org/uniprotkb/Q9VMD5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 305, "end_pos": 307, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "12937", "name": "", "equation": "a 1-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q0KHU5-1", "Q6NN55-1", "Q9VMD5-1", "Q9VVX5-1" ], "evidence": [ { "id": "12937", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/12937" } ] }, { "id": "32995", "name": "", "equation": "a 1-acyl-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q6NN55-1", "Q9VMD5-1" ], "evidence": [ { "id": "32995", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/32995" } ] }, { "id": "33191", "name": "", "equation": "a 1-acyl-sn-glycero-3-phospho-L-serine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phospho-L-serine + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q6NN55-1", "Q9VMD5-1", "Q9VVX5-1" ], "evidence": [ { "id": "33191", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/33191" } ] }, { "id": "37015", "name": "", "equation": "a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = a 1-acyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VMD5-1" ], "evidence": [ { "id": "37015", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/37015" } ] }, { "id": "37207", "name": "", "equation": "(9Z)-hexadecenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-(9Z-hexadecenoyl)-sn-glycero-3-phosphocholine + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q6NN55-1", "Q9VVX5-1", "Q9VMD5-1" ], "evidence": [ { "id": "37207", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/37207" } ] }, { "id": "37399", "name": "", "equation": "1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + (9Z)-hexadecenoyl-CoA = 1-(9Z-octadecenoyl)-2-(9Z-hexadecenoyl)-sn-glycero-3-phospho-L-serine + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q6NN55-1", "Q9VVX5-1", "Q9VMD5-1" ], "evidence": [ { "id": "37399", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/37399" } ] }, { "id": "37419", "name": "", "equation": "1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + (9Z)-hexadecenoyl-CoA = 1-hexadecanoyl-2-(9Z)-hexadecenoyl-sn-glycero-3-phosphoethanolamine + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q6NN55-1", "Q9VMD5-1" ], "evidence": [ { "id": "37419", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/37419" } ] }, { "id": "R-DME-1482598", "name": "1-acyl LPI is acylated to PI by MBOAT7", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [ "R-ALL-1498733" ], "output_participant_list": [], "enzyme_list": [ "Q9VMD5-1" ], "evidence": [ { "id": "R-DME-1482598", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1482598" } ] }, { "id": "R-DME-1482626", "name": "2-acyl LPI is acylated to PI by MBOAT7", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [ "R-ALL-1498737" ], "output_participant_list": [], "enzyme_list": [ "Q9VMD5-1" ], "evidence": [ { "id": "R-DME-1482626", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1482626" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-1498733", "participant_name": "1-acyl LPI [endoplasmic reticulum membrane]", "crossref": [ { "id": "28914", "database": "ChEBI", "url": "" }, { "id": "C03819", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-1498737", "participant_name": "2-acyl LPI [endoplasmic reticulum membrane]", "crossref": [ { "id": "62746", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "Q0KHU5", "gene_name": "LPCAT", "activity": [ { "ec_number": "2.3.1.23", "activity": "a 1-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA.", "evidence": [ { "id": "Q0KHU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0KHU5" } ] } ] }, { "uniprot_ac": "Q6NN55", "gene_name": "oys", "activity": [ { "ec_number": "2.3.1.23", "activity": "a 1-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA.", "evidence": [ { "id": "Q6NN55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6NN55" } ] }, { "ec_number": "2.3.1.n6", "activity": "a 1-acyl-sn-glycero-3-phospho-L-serine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phospho-L-serine + CoA.", "evidence": [ { "id": "Q6NN55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6NN55" } ] }, { "ec_number": "2.3.1.n7", "activity": "a 1-acyl-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CoA.", "evidence": [ { "id": "Q6NN55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6NN55" } ] }, { "ec_number": "2.3.1.-", "activity": "", "evidence": [ { "id": "Q6NN55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6NN55" } ] }, { "ec_number": "2.3.1.n7", "activity": "", "evidence": [ { "id": "Q6NN55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6NN55" } ] }, { "ec_number": "2.3.1.23", "activity": "", "evidence": [ { "id": "Q6NN55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6NN55" } ] }, { "ec_number": "2.3.1.n6", "activity": "", "evidence": [ { "id": "Q6NN55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6NN55" } ] } ] }, { "uniprot_ac": "Q9VMD5", "gene_name": "frj", "activity": [ { "ec_number": "2.3.1.23", "activity": "a 1-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA.", "evidence": [ { "id": "Q9VMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMD5" } ] }, { "ec_number": "2.3.1.n6", "activity": "a 1-acyl-sn-glycero-3-phospho-L-serine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phospho-L-serine + CoA.", "evidence": [ { "id": "Q9VMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMD5" } ] }, { "ec_number": "2.3.1.n7", "activity": "a 1-acyl-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CoA.", "evidence": [ { "id": "Q9VMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMD5" } ] }, { "ec_number": "2.3.1.-", "activity": "", "evidence": [ { "id": "Q9VMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMD5" } ] }, { "ec_number": "2.3.1.n7", "activity": "", "evidence": [ { "id": "Q9VMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMD5" } ] }, { "ec_number": "2.3.1.23", "activity": "", "evidence": [ { "id": "Q9VMD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMD5" } ] }, { 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"https://data.glygen.org/ln2downloads/pdb/current/AF-Q9VMD5-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q9VMD5" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.1.23", "ec_name": "a 1-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA.", "evidence": [ { "id": "2.3.1.23", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.23" }, { "id": "2.3.1.23", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.1.23" } ] }, { "ec_number": "2.3.1.n6", "ec_name": "a 1-acyl-sn-glycero-3-phospho-L-serine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phospho-L-serine + CoA.", "evidence": [ { "id": "2.3.1.n6", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.n6" } ] }, { "ec_number": "2.3.1.n7", "ec_name": "a 1-acyl-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VME5" } ] }, { "name": "slam", "type": "synonym", "evidence": [ { "id": "NP_001285668", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285668" } ] }, { "name": "wdo", "type": "synonym", "evidence": [ { "id": "NP_001285668", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285668" }, { "id": "Q9VME5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VME5" } ] } ], "protein_names": [ { "name": "CG9506-PC", "type": "synonym", "evidence": [ { "id": "NP_001285668", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285668" } ] }, { "name": "Slow as molasses, isoform B", "type": "synonym", "evidence": [ { "id": "Q9VME5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VME5/entry#names_and_taxonomy" } ] }, { "name": "Slow as molasses, isoform C", "type": "synonym", "evidence": [ { "id": "Q9VME5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VME5/entry#names_and_taxonomy" } ] }, { "name": "slam-PC", "type": "synonym", "evidence": [ { "id": "NP_001285668", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285668" } ] }, { "name": "slow as molasses, isoform C", "type": "synonym", "evidence": [ { "id": "NP_001285668", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285668" } ] }, { "name": "waldo", "type": "synonym", "evidence": [ { "id": "NP_001285668", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285668" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VME5", "url": "https://www.uniprot.org/uniprotkb/Q9VME5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "slam", "url": "https://www.uniprot.org/uniprotkb/Q9VME5", "locus": { "chromosome": "2L", "start_pos": 6377284, "end_pos": 6372388, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0043854", "url": "https://www.ensemblgenomes.org/id/FBgn0043854" } ] } } ], "crossref": [ { "id": "FB:FBgn0043854", "url": "https://alliancegenome.org/gene/FB:FBgn0043854", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0043854", "url": "https://bgee.org/?page=gene&gene_id=FBgn0043854", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0043854", "url": "https://flybase.org/reports/FBgn0043854", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "33890", "url": "https://www.ncbi.nlm.nih.gov/gene/33890", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VME5", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VME5*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "dme:Dmel_CG9506", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG9506", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AKHPKFN", "url": "https://omabrowser.org/oma/group/AKHPKFN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VME5", "url": "https://www.orthodb.org/?gene=Q9VME5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "NP_001285668", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285668", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VME5", "url": "https://www.uniprot.org/uniprotkb/Q9VME5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VME5-1", "url": "https://www.uniprot.org/uniprotkb/Q9VME5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVLSNSTPNNQSKHNQMVVDTAAMNSDDLSELLQLNAEIEERRRSSRHGDASTACGLLRATMTREELFEISSLDDDRFLTALEYQNSFASPRRVQVTDLDLSSIENLMKYFDEEVPVTPTKTLGTTKAAGNTGKVASTIAKLALQSDPVTPPKPKVGSGHLKISELKQKYEQLPEMETPRSAYQASRKVSASLPMKVKEMAQLFNSKISQVMRRTEEPQYVQLQNEMSPEVKAQNRLVSPLESPVQGPCLVAEEVFRELSVKDKALLFNKFIGDMAAKHPKFTAHAADLKEKVNKQVARGEVVAERQASVKHLAQELEAKCILEPGSPPRPGGVSPPKTTESKTETCTSQLHVSTLTVILKPSPERRAPQPRPRRCLDRQSDEHAREPSQKRNLAAIRTMMPTEAYAPPKKIRRTRQERTGADSQMFFQNEHLETLFYSWLSSENGVQFDITSVSDGQQTIEIATEEGNLLEQPLLEPSTATLEDVSQKSAVERLLEEAIAKLELDNESKKETQVEEKKEMDTAQDPIVQVTPRRIKRQAPPVPAPRPSLSQVTSSASSCKQSEAEESESGLSTLPKITSDESQPETPKDDLQTGEFDFAKPQRPPRKKKMRRTLTWKKENSIVEATAITSTDSDSDYKPPLSGAAKKKSGAICNPLPMPEPSFIELDKSLMRHLNSPRKIKSAYTLTVMSSPSPNADSDQSPSQTPRQSLVQAMRDSFVDQGFETCSNDPMDNSPIRRSSLGATESKPSGFSTPVKGRHASSPAQQQLFSPILIQERPRRSSLAMQVIREDHPLDLDATSSSPSTPCSEREFFANAPTVEIDNSQDESPTGKAHSMFWITSGDFTVSLEIFKNSPERLRLLYEIFTQKSWETRDLAFGIDGHKFIRGAPSSDSVRQSLPERPPSVKGCSHYWFASGDLAVPFSGKLMSSEKIERLFAFLSGEQSELRFGVDHIEFSSVPEFWPTTQKYSIESSYSILVGLQTGASNGLEGRSKYSWPNSSISANQAIKTSDLDQTEFESDSFGNNSGRLSFSPDLFSLDYEAVPLDELFAKAPPSAATPAMSVPQMMQTLKQQQSKLRSVEQRIRGYAKPANLADSSLEHCRNTPQYVHKLRSIIRAIDNIGRDDGFRGCSMEQLESFMYFLSEYADVCLANCSEHMDKILDTLMDRRAVEV", "length": 1173, "header": "tr|Q9VME5-1|Q9VME5_DROME Isoform 1 of Slow as molasses, isoform C OS=Drosophila melanogaster OX=7227 GN=slam PE=4 SV=3 CANONICAL=Q9VME5-1" }, "isoforms": [ { "isoform_ac": "Q9VME5-1", "url": "https://www.uniprot.org/uniprotkb/Q9VME5/entry#Q9VME5-1", "sequence": { "sequence": "MVLSNSTPNNQSKHNQMVVDTAAMNSDDLSELLQLNAEIEERRRSSRHGDASTACGLLRATMTREELFEISSLDDDRFLTALEYQNSFASPRRVQVTDLDLSSIENLMKYFDEEVPVTPTKTLGTTKAAGNTGKVASTIAKLALQSDPVTPPKPKVGSGHLKISELKQKYEQLPEMETPRSAYQASRKVSASLPMKVKEMAQLFNSKISQVMRRTEEPQYVQLQNEMSPEVKAQNRLVSPLESPVQGPCLVAEEVFRELSVKDKALLFNKFIGDMAAKHPKFTAHAADLKEKVNKQVARGEVVAERQASVKHLAQELEAKCILEPGSPPRPGGVSPPKTTESKTETCTSQLHVSTLTVILKPSPERRAPQPRPRRCLDRQSDEHAREPSQKRNLAAIRTMMPTEAYAPPKKIRRTRQERTGADSQMFFQNEHLETLFYSWLSSENGVQFDITSVSDGQQTIEIATEEGNLLEQPLLEPSTATLEDVSQKSAVERLLEEAIAKLELDNESKKETQVEEKKEMDTAQDPIVQVTPRRIKRQAPPVPAPRPSLSQVTSSASSCKQSEAEESESGLSTLPKITSDESQPETPKDDLQTGEFDFAKPQRPPRKKKMRRTLTWKKENSIVEATAITSTDSDSDYKPPLSGAAKKKSGAICNPLPMPEPSFIELDKSLMRHLNSPRKIKSAYTLTVMSSPSPNADSDQSPSQTPRQSLVQAMRDSFVDQGFETCSNDPMDNSPIRRSSLGATESKPSGFSTPVKGRHASSPAQQQLFSPILIQERPRRSSLAMQVIREDHPLDLDATSSSPSTPCSEREFFANAPTVEIDNSQDESPTGKAHSMFWITSGDFTVSLEIFKNSPERLRLLYEIFTQKSWETRDLAFGIDGHKFIRGAPSSDSVRQSLPERPPSVKGCSHYWFASGDLAVPFSGKLMSSEKIERLFAFLSGEQSELRFGVDHIEFSSVPEFWPTTQKYSIESSYSILVGLQTGASNGLEGRSKYSWPNSSISANQAIKTSDLDQTEFESDSFGNNSGRLSFSPDLFSLDYEAVPLDELFAKAPPSAATPAMSVPQMMQTLKQQQSKLRSVEQRIRGYAKPANLADSSLEHCRNTPQYVHKLRSIIRAIDNIGRDDGFRGCSMEQLESFMYFLSEYADVCLANCSEHMDKILDTLMDRRAVEV", "length": 1173, "header": "tr|Q9VME5-1|Q9VME5_DROME Isoform 1 of Slow as molasses, isoform C OS=Drosophila melanogaster OX=7227 GN=slam PE=4 SV=3 CANONICAL=Q9VME5-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1059, "start_aa": "Thr", "end_pos": 1059, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1059", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 150, "start_aa": "Thr", "end_pos": 150, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr150", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VME5", "url": "https://www.uniprot.org/uniprotkb/Q9VME5" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VME5", "url": "https://www.uniprot.org/uniprotkb/Q9VME5" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VME5", "url": "https://www.uniprot.org/uniprotkb/Q9VME5" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VME5", "url": "https://www.uniprot.org/uniprotkb/Q9VME5" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VME5", "url": "https://www.uniprot.org/uniprotkb/Q9VME5" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VME5", "url": "https://www.uniprot.org/uniprotkb/Q9VME5" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VME5", "url": "https://www.uniprot.org/uniprotkb/Q9VME5" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VME5", "url": "https://www.uniprot.org/uniprotkb/Q9VME5" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VME5", "url": "https://www.uniprot.org/uniprotkb/Q9VME5" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VME5", "url": "https://www.uniprot.org/uniprotkb/Q9VME5" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VME5", "url": "https://www.uniprot.org/uniprotkb/Q9VME5" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], 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"germ cell migration", "id": "GO:0008354", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008354", "evidence": [ { "database": "UniProtKB", "id": "Q9VME5", "url": "https://www.uniprot.org/uniprotkb/Q9VME5" } ], "pmid": "" }, { "name": "cleavage furrow formation", "id": "GO:0036089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036089", "evidence": [ { "database": "UniProtKB", "id": "Q9VME5", "url": "https://www.uniprot.org/uniprotkb/Q9VME5" } ], "pmid": "" }, { "name": "cellularization", "id": "GO:0007349", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007349", "evidence": [ { "database": "UniProtKB", "id": "Q9VME5", "url": "https://www.uniprot.org/uniprotkb/Q9VME5" } ], "pmid": "" }, { "name": "syncytial embryo cellularization", "id": "GO:0110069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110069", "evidence": [ { "database": "UniProtKB", "id": "Q9VME5", "url": "https://www.uniprot.org/uniprotkb/Q9VME5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, 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"MRTLSVLILLATLVAFCAAQQASNGKNRKENAFSKIVPRLLWNIKRGDQESHRNSQQPIIIVQQPSSNQESDRHHHHNPNYPYYPYYPPPPPQNRPPPPFPGMDWNTVGGGPTYLIINPNNMQGIYLPASSNSSNSTSSRRSAFVPTISDLLQGLNLDDLADGSLFEDDSEVVNAAEDGNAEIPLADGPISQADDDREEDVISEDEIDAMDRQSNRGLSPKHLVSILMQDKRRRRIQEVLAGIYLRNYNLNRK", "length": 253, "header": "tr|Q9VMF9-1|Q9VMF9_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG13983 PE=4 SV=1 CANONICAL=Q9VMF9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VMF9", "url": "https://www.uniprot.org/uniprotkb/Q9VMF9" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VMF9", "url": "https://www.uniprot.org/uniprotkb/Q9VMF9" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMF9", "url": "https://www.uniprot.org/uniprotkb/Q9VMF9" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMF9", "url": "https://www.uniprot.org/uniprotkb/Q9VMF9" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VMF9", "url": "https://www.uniprot.org/uniprotkb/Q9VMF9" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VMF9", "url": "https://www.uniprot.org/uniprotkb/Q9VMF9" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VMF9", "url": "https://www.uniprot.org/uniprotkb/Q9VMF9" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMF9", "url": "https://www.uniprot.org/uniprotkb/Q9VMF9" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMF9", "url": "https://www.uniprot.org/uniprotkb/Q9VMF9" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VMG1", "url": "https://www.uniprot.org/uniprotkb/Q9VMG1" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VMG1", "url": "https://www.uniprot.org/uniprotkb/Q9VMG1" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMG1", "url": "https://www.uniprot.org/uniprotkb/Q9VMG1" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMG1", "url": "https://www.uniprot.org/uniprotkb/Q9VMG1" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VMG1", "url": "https://www.uniprot.org/uniprotkb/Q9VMG1" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VMG1", "url": "https://www.uniprot.org/uniprotkb/Q9VMG1" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VMG1", "url": "https://www.uniprot.org/uniprotkb/Q9VMG1" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMG1", "url": "https://www.uniprot.org/uniprotkb/Q9VMG1" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMG1", "url": "https://www.uniprot.org/uniprotkb/Q9VMG1" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VMG1", "url": "https://www.uniprot.org/uniprotkb/Q9VMG1" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VMG1", "url": "https://www.uniprot.org/uniprotkb/Q9VMG1" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG9481", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG9481", "resource": "KEGG Pathway" }, { "id": "R-DME-9753281", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9753281", "resource": "Reactome", "description": "Paracetamol ADME" }, { "id": "R-DME-9757110", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9757110", "resource": "Reactome", "description": "Prednisone ADME" }, { "id": "R-DME-9840309", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9840309", "resource": "Reactome", "description": "Glycosphingolipid biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1NVN7-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "ugt1a5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASVLLFCLFCLASAKAGKILVVPSDGSHWMGIKPLVEELGRRGNQVVVVIPEASLSMGPSQHTTTLTYPVPYTKAQIQDHISASVTNLISTHVSTDLARFQSFINTMDLLSNLITRNVEGLLLNKDLMKKLQDYNFDVILTDPFETVGVIAAEYLSIPTIYIQTSHPCGADTLASQCPSPPSYVPQRLTHFSDRMNLWQRSVNFVRTLIQPMACRRMFTRADEIASRVLQRKTSIMDIMGRAALWFVHSDFALEFPHPLMPNMIIVGGMDNRKAEPLSQELEEFVNGSGEHGFVVFTLGSMVSQLPEAKAREFFEAFRQIPQRVLWRYTGPVPENAPKNVKLMKWLPQNDLLGHPKVRAFVTHGGSHGIYEGICNGVPMVMLPLFGDQGDNAQRLVSRGVAESLTIYDVTSEKLLVALKKVINDKSYKEKMMKLSAIHRDRPIEPLDLAVFWTEFVMRHKGAEHLRPAAHDLNWIQYHSLDVIGFLLLILLTVIFVTVKSCMFCFRKCFKKSQKKKKA", "length": 519 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" }, { "id": "FB:FBgn0026755", "url": "https://alliancegenome.org/gene/FB:FBgn0026755#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1NX95-1", "protein_name": "glucuronosyltransferase", "gene_name": "ugt2a1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSPRGSTGVFLLLALLLNQNLLCVSGGKILVWPAEFSHWLNIKVILDVLIERGHNITVVTHTATPSVQTTPSAGYNAEILQVPYTKQEIVDNLERMLKYWTHDLPNDNIITASLKIHEMITTATAQNKITCNALFSRADLLEKWKMEKFDVILADPLYICGEILAQKLDIPLIFSLRFTFGNTLERLCGQMPAPPSYVPAVASEKTDQMDFIDRLKNFLFYGMQDFLFYLVTKFKWDHYYSEVLGKPTTMCETMGKADIWLIRTYWDFEYPRPFPPNFKFVGGLHCKPAKPLSKEMEEFVQSSGDHGVVVFSLGSMIKNLTSERANTIAAALGQIPQKVVWRYSGKTPETLAPNTKIYDWIPQNDLLGHPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFADQPDNLLHMKTKGAAVVLDINTLESKDLVDALKTVLNNPSYKESIMRLSRIHHDQPMKPLDQAVYWIEFVMRNKGAKHLRVQAHELSWYQYHCLDVAAFLLSIAALITFLWVKACCFLFRRCVRKTRPERKTQKSKNE", "length": 539 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB12ZY70-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "ugt2b6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRPLACFLSLLSLLSAGECGNVLVWFTEGSHWINMKIVLETLIDRGHDVTVLVPDASLFMKANASDRFSYQPFNVSMDEQEMKVFIEEFLYFSLYEMDQLNFFQMQSKVYEFTSKLQDMSISYCDGVLKSPGLLDKLRKHKFDVVFSDPIYQCSDIVAEELNVPLVYTFRFSLAHAAERMCGQIPAPPSYVPGAMSKLTDKMSFTERIYNMLFYLSQDAFAIFAWKKIDNYYTEYFGRPTSYCEMMGRADIWLIRTYWDFEFPRPFVPNFKYIGGLHCTPAKPLPKDMEEFVQSSGEDGIVVFTLGSLVGKVPKEISNRIASALAQIPQKVLWRYGGEKPDTLGENTRIYKWIPQNDLLGHPKTRAFITHGGTNGVYEAIYHGVPMVGIPLFGDQPDNMVHMTTRGAAVVVDSIKSMQPQELVDKLNTVINDPSYKENAMRLSRIHHDRPMKPLDESVFWIEFVMRNKGAKHLRVEAHNLTWYQYHCLDVFAFLTTVLTLVLYICFKMAKFFIMRCCFRSKRKSKKE", "length": 527 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" }, { "id": "FB:FBgn0026755", "url": "https://alliancegenome.org/gene/FB:FBgn0026755#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABK0L4Q8-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "LOC134478834", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFKMPRKWISALFLLQISYCFKSGHCGKVLVWPMDFSHWMNIKIILDELVQRGHEVTVLKPSAYFFLDPKKSSDLKFEIFPTSISKDELQNHFIKLLDVWTYELPRDTCLSYSPILQNLVYEFSYFYLSICKDAVSNKQLMTKLQESKFDVLFADPVASCGDLIAELLHIPFLYSLSFSPGHKLEKSIGKFILPPSYVPVILSGLAGKMTFIDRVKNMICMLYFDFWFERLRHKEWDTFYSEILGRPTTVDETMSKVEIWLIRSYWDLKFPHPTLPNVDYIGGLHCKPAKPLPKDMEEFVQSSGEHGVVVFSLGSMVSNMTEEKANAIAWALAQIPQKVLWKFDGKTPATLGPNTRVYKWLPQNDILGHPKTKAFVTHGGANGLYEAIYHGIPMIGIPLFGDQPDNIAHMVAKGAAVSLNIRTMSKLDFLSALEEVIDNPFYKKNVMLLSTIHHDQPMKPLDRAVFWIEFIMRHKGAKHLRPLGHNLPWYQYHSLDVIGFLLTCFAVIAALTVKCLLFMYRFFVKKEKKMKNE", "length": 533 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LGK3-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt2b37", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPGKWIFALLLLQISFCLRSAKCGKVLVWPMEFSHWMNIKTILDELVQRGHEVTVLKPSAYYVLDPKKSPDLKFETFPTSVSKDELEKYFIKLVDAWTYELQRDTCLSFSPLLQNMMDEFSDYYLSVCKDAVSNKQLMAKLQESKFDVLLSDPVAACGELIAEVLHIPFLYSLRASPGHKIEKSSGRFILPPSYVPVILSGLGGQMTFIDRVKNMICMLYFDFWFHMFNAKNWDPFYTEILGRPTTLAETMGKAEMWLIRSYWDLEFPHPTLPNVDYIGGLQCKPAKPLPKDIEDFVQSSGEHGVVVFSLGSMVSSMTEEKANAVAWALAQIPQKVLWKFDGKIPATLGPNTRVYKWLPQNDLLGHPKTKAFVTHGGANGVYEAIYHGIPMIGIPMFGEQHDNIAHMVAKGAAVTLNIRTMSKSDLFNALKEVINNPFYKKNAMWLSTIHHDQPMKPLDKAIFWIEYVMRHKRAKHLRPLGHNLPWYQYHSLDVIGFLLACLAVIAALAVKCFLFIYRFFAKKQKKMKNE", "length": 530 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B8JMA2-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "ugt2a5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTSGALLVCLLLCGVDVGWSGRVLVMPGEYSHWHNMRPVIEALVDKNHSVTVLVGSSSPTVPHTQKERFEYHVFKVNMEKEEADAAMRDMIHLFTNDTAAKYEGEFVMWKVMSKFVEFGDVYFRGLFDVGLLKTLRDSNYDVLFSDPMMPFSDLMAQKLNIPQVISMRATFAYAAERLCGQMPAPPSYVPAVALTDHLTDRMSFMERVENMLLYIVHSIAFPLVATFTFDGYYSEILGKPTTMCETMGKVDICLIRTYWDFEYPRPFPPNFKFVGGLHCKPAKPLSKELEEFVQSSGDHGVVVFSLGSMIKNLTSERANTIAAALGQIPQKVVWRYSGKTPETLAPNTKIYDWIPQNDLLGHPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFGDQPDNLLHIKTKGAAVVLDIHTMGSKDLVDALKAVVNNPSYKESIMRLSRIHHDQPMKPLDQAVYWIEFVMRNKGAKHLRVQAHELSWYQYHCLDVAAFLLSITALITFLWVKACCFLFRRCVRKTRPERKRQKNKKE", "length": 532 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3Z748-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt1a8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPAVFPASLPLRVCLLLAFGLAQAGRLLVVPMDGSHWFSMKMIVEKLSHRGHEVVVVIPEVSWHLGKSQNFTVKTYSVSYTLEDLSHHFNFFAHKQWENREVGMFSLLKHSGKGFFQVLFSHCRSLFNDKKLVEYLKQRSFDAVFLDPFDVCGLTIAKYFSLPSVVFSGGIFCHYLDEGAQCPSPPSYVPRILSKFADTMTFKERVWNYFSYMKERAFCPYFFKTAIEIASEVLQTPVTMTDLFSSVSIWMFRTDFVLEFPRPVMPNMVYIGGINCHPGKPLSKEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVFKCCAYGCRKCFGGKGRVKKSHKSKTH", "length": 530 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1LTB8-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt2b34l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVKMTAALLLLHLTIFFGSGSGGKVLVWPVEFSHWLNLKIILSELVKKGHEVVVLKPSVSFSYEVDKTSAIEFESFPSSYSIADVEVIFMDCVNESIYELPKQSFWGYFLMLQKLFERTSDYSERLCRDAAFNKELMTKLQNSGFDVILADPFTPCGDLLAEILKIPLVYSLRFFPGSTYEKYSGGLPMPPSYVPIAMSELSDRMTFVERVKHMIYVLCFDFWFQVFDEKKWNELYTEVLGRPTTLSETMAKADIWLIRTYWDLEFPHPVLPNFDFVGGLHCRPAKPLPKEIEDFVQSSGEHGVVVFSLGSMVGSLTEERANVIAAGLAQIPQKVLWRFEGKKPETLGSNTRLYKWIPQNDLLGHPKTRAFITHGGTNGIYEAIYHGIPVVGIPLFGDQKDNIVHLKTKGAAVRLDFLTMSSTDLLTALRTVTNDPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAGHDLSWVQYHSLDVIGFLLACVVTVMFILKKCCLFCCQKFTKAGRKKKKE", "length": 530 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "K9J7B2-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt1a6b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MACLLPAAQTLPAGFLFLVLWASVLGDKLLVVPQDGSHWLSMKEIVEHLSERGHDIVVLVPEVNLLLGESKYYRRKIFSVPYSLEELQTRFRTFGRNQFVPGAPLMGPLREYRNSMLTLEMFFSNCQSLLKDSATLSFLRENKFDALFTDPAMPCGVILAEYLNLPSVYLFRGFPCSLEHMLGQSPSPVSYVPRFYTKFSDHMTFPQRLANFIVNILENYLYYCLYSKYEIIVTDLLKRDVSLPSLHQNSLWLLRYDFVFEYPRPIMPNMIFIGGINCKKKGKLTQEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVFKCCAYGCRKCFGGKGRVKKSHKSKTH", "length": 531 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O60656-1", "protein_name": "UDP-glucuronosyltransferase 1A9", "gene_name": "UGT1A9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MACTGWTSPLPLCVCLLLTCGFAEAGKLLVVPMDGSHWFTMRSVVEKLILRGHEVVVVMPEVSWQLGRSLNCTVKTYSTSYTLEDLDREFKAFAHAQWKAQVRSIYSLLMGSYNDIFDLFFSNCRSLFKDKKLVEYLKESSFDAVFLDPFDNCGLIVAKYFSLPSVVFARGILCHYLEEGAQCPAPLSYVPRILLGFSDAMTFKERVRNHIMHLEEHLLCHRFFKNALEIASEILQTPVTEYDLYSHTSIWLLRTDFVLDYPKPVMPNMIFIGGINCHQGKPLPMEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH", "length": 530 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O75310-1", "protein_name": "UDP-glucuronosyltransferase 2B11", "gene_name": "UGT2B11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTLKWTSVLLLIHLSCYFSSGSCGKVLVWAAEYSHWMNMKTILKELVQRGHEVTVLASSASILFDPNDASTLKFEVYPTSLTKTEFENIIMQQVKRWSDIRKDSFWLYFSQEQEILWELYDIFRNFCKDVVSNKKVMKKLQESRFDIVFADAVFPCGELLAALLNIRFVYSLRFTPGYTIERHSGGLIFPPSYIPIVMSKLSDQMTFMERVKNMIYVLYFDFWFQMSDMKKWDQFYSEVLGRPTTLFETMGKADIWLMRNSWSFQFPHPFLPNVDFVGGFHCKPAKPLPKEMEEFVQSSGENGVVVFSLGSVISNMTAERANVIATALAKIPQKVLWRFDGNKPDALGLNTRLYKWIPQNDLLGHPKTRAFITHGGANGIYEAIYHGIPMVGIPLFFDQPDNIAHMKAKGAAVRLDFNTMSSTDLLNALKTVINDPLYKENIMKLSRIQHDQPVKPLDRAVFWIEFVMPHKGAKHLRVAAHDLTWFQYHSLDVIGFLLACVATVIFIITKFCLFCFWKFARKGKKGKRD", "length": 529 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O75795-1", "protein_name": "UDP-glucuronosyltransferase 2B17", "gene_name": "UGT2B17", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLKWMSVFLLMQLSCYFSSGSCGKVLVWPTEYSHWINMKTILEELVQRGHEVIVLTSSASILVNASKSSAIKLEVYPTSLTKNDLEDFFMKMFDRWTYSISKNTFWSYFSQLQELCWEYSDYNIKLCEDAVLNKKLMRKLQESKFDVLLADAVNPCGELLAELLNIPFLYSLRFSVGYTVEKNGGGFLFPPSYVPVVMSELSDQMIFMERIKNMIYMLYFDFWFQAYDLKKWDQFYSEVLGRPTTLFETMGKAEMWLIRTYWDFEFPRPFLPNVDFVGGLHCKPAKPLPKEMEEFVQSSGENGIVVFSLGSMISNMSEESANMIASALAQIPQKVLWRFDGKKPNTLGSNTRLYKWLPQNDLLGHPKTKAFITHGGTNGIYEAIYHGIPMVGIPLFADQHDNIAHMKAKGAALSVDIRTMSSRDLLNALKSVINDPIYKENIMKLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHNLTWIQYHSLDVIAFLLACVATMIFMITKCCLFCFRKLAKTGKKKKRD", "length": 530 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P06133-1", "protein_name": "UDP-glucuronosyltransferase 2B4", "gene_name": "UGT2B4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSMKWTSALLLIQLSCYFSSGSCGKVLVWPTEFSHWMNIKTILDELVQRGHEVTVLASSASISFDPNSPSTLKFEVYPVSLTKTEFEDIIKQLVKRWAELPKDTFWSYFSQVQEIMWTFNDILRKFCKDIVSNKKLMKKLQESRFDVVLADAVFPFGELLAELLKIPFVYSLRFSPGYAIEKHSGGLLFPPSYVPVVMSELSDQMTFIERVKNMIYVLYFEFWFQIFDMKKWDQFYSEVLGRPTTLSETMAKADIWLIRNYWDFQFPHPLLPNVEFVGGLHCKPAKPLPKEMEEFVQSSGENGVVVFSLGSMVSNTSEERANVIASALAKIPQKVLWRFDGNKPDTLGLNTRLYKWIPQNDLLGHPKTRAFITHGGANGIYEAIYHGIPMVGVPLFADQPDNIAHMKAKGAAVSLDFHTMSSTDLLNALKTVINDPLYKENAMKLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLTWFQYHSLDVTGFLLACVATVIFIITKCLFCVWKFVRTGKKGKRD", "length": 528 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "FB:FBgn0026755", "url": "https://alliancegenome.org/gene/FB:FBgn0026755#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P08430-1", "protein_name": "UDP-glucuronosyltransferase 1A6", "gene_name": "Ugt1a6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MACLLPAARLPAGFLFLVLWGSVLGDKLLVVPQDGSHWLSMKEIVEHLSERGHDIVVLVPEVNLLLGESKYYRRKSFPVPYNLEELRTRYRSFGNNHFAASSPLMAPLREYRNNMIVIDMCFFSCQSLLKDSATLSFLRENQFDALFTDPAMPCGVILAEYLKLPSIYLFRGFPCSLEHIGQSPSPVSYVPRFYTKFSDHMTFPQRLANFIANILENYLYHCLYSKYEILASDLLKRDVSLPALHQNSLWLLRYDFVFEYPRPVMPNMIFIGGTNCKKKGNLSQEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTLLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKARAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVYKSCAYGCRKCFGGKGRVKKSHKSKTH", "length": 529 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P08542-1", "protein_name": "UDP-glucuronosyltransferase 2B17", "gene_name": "Ugt2b17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPGKWISALLLLQISCCFQSGNCGKVLVWPMEFSHWMNIKTILDELVQRGHEVTVLKPSAYYVLDPKKSPDLKFETFPTSVSKDELENYFIKLVDVWTYELQRDTCLSYSPLLQNMIDGFSDYYLSLCKDTVSNKQLMAKLQESKFDVLLSDPVAACGELIAEVLHIPFLYSLRFSPGYKIEKSSGRFILPPSYVPVILSGMGGPMTFIDRVKNMICTLYFDFWFHMFNAKKWDPFYSEILGRPTTLAETMGKAEMWLIRSYWDLEFPHPTLPNVDYIGGLQCRPPKPLPKDMEDFVQSSGEHGVVVFSLGSMVSSMTEEKANAIAWALAQIPQKVLWKFDGKTPATLGPNTRVYKWLPQNDLLGHPKTKAFVTHSGANGVYEAIYHGIPMVGIPMFGEQHDNIAHMVAKGAAVTLNIRTMSKSDLFNALKEIINNPFYKKNAVWLSTIHHDQPMKPLDKAVFWIEFVMRHKGAKHLRPLGHDLPWYQYHSLDVIGFLLTCSAVIAVLTVKCFLFIYRLFVKKEKKMKNE", "length": 530 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P09875-1", "protein_name": "UDP-glucuronosyltransferase 2B1", "gene_name": "Ugt2b1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSMKQTSVFLLIQLICYFRPGACGKVLVWPTEYSHWINIKIILNELAQRGHEVTVLVSSASILIEPTKESSINFEIYSVPLSKSDLEYSFAKWIDEWTRDFETLSIWTYYSKMQKVFNEYSDVVENLCKALIWNKSLMKKLQGSQFDVILADAVGPCGELLAELLKTPLVYSLRFCPGYRCEKFSGGLPLPPSYVPVVLSELSDRMTFVERVKNMLQMLYFDFWFQPFKEKSWSQFYSDVLGRPTTLTEMMGKADIWLIRTFWDLEFPHPFLPNFDFVGGLHCKPAKPLPREMEEFVQSSGEHGVVVFSLGSMVKNLTEEKANVVASALAQIPQKVVWRFDGKKPDTLGSNTRLYKWIPQNDLLGHPKTKAFVAHGGTNGIYEAIYHGIPIVGIPLFADQPDNINHMVAKGAAVRVDFSILSTTGLLTALKIVMNDPSYKENAMRLSRIHHDQPVKPLDRAVFWIEYVMRHKGAKHLRSTLHDLSWFQYHSLDVIGFLLLCVVGVVFIITKFCLFCCRKTANMGKKKKE", "length": 529 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0DTE4-5", "protein_name": "UDP-glucuronosyltransferase 2A1", "gene_name": "UGT2A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLNNLLLFSLQISLIGTTLGGNVLIWPMEGSHWLNVKIIIDELIKKEHNVTVLVASGALFITPTSNPSLTFEIYKVPFGKERIEGVIKDFVLTWLENRPSPSTIWRFYQEMAKVIKDFHMVSQEICDGVLKNQQLMAKLKKSKFEVLVSDPVFPCGDIVALKLGIPFMYSLRFSPASTVEKHCGKVPYPPSYVPAVLSELTDQMSFTDRIRNFISYHLQDYMFETLWKSWDSYYSKALGGLLLCCPGWSAVADLGSLQPLLPGFKRFSRLSLHCSWDYRLPAGRPTTLCETMGKAEIWLIRTYWDFEFPRPYLPNFEFVGGLHCKPAKPLPKVLWRYKGKKPATLGNNTQLFDWIPQNDLLGHPKTKAFITHGGTNGIYEAIYHGVPMVGVPMFADQPDNIAHMKAKGAAVEVNLNTMTSVDLLSALRTVINEPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLTWFQYHSLDVIGFLLVCVTTAIFLVIQCCLFSCQKFGKIGKKKKRE", "length": 527 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DTE5-1", "protein_name": "UDP-glucuronosyltransferase 2A2", "gene_name": "UGT2A2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVSIRDFTMPKKFVQMLVFNLTLTEVVLSGNVLIWPTDGSHWLNIKIILEELIQRNHNVTVLASSATLFINSNPDSPVNFEVIPVSYKKSNIDSLIEHMIMLWIDHRPTPLTIWAFYKELGKLLDTFFQINIQLCDGVLKNPKLMARLQKGGFDVLVADPVTICGDLVALKLGIPFMYTLRFSPASTVERHCGKIPAPVSYVPAALSELTDQMTFGERIKNTISYSLQDYIFQSYWGEWNSYYSKILGRPTTLCETMGKAEIWLIRTYWDFEFPRPYLPNFEFVGGLHCKPAKPLPKEMEEFIQSSGKNGVVVFSLGSMVKNLTEEKANLIASALAQIPQKVLWRYKGKKPATLGNNTQLFDWIPQNDLLGHPKTKAFITHGGTNGIYEAIYHGVPMVGVPMFADQPDNIAHMKAKGAAVEVNLNTMTSVDLLSALRTVINEPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLTWFQYHSLDVIGFLLVCVTTAIFLVIQCCLFSCQKFGKIGKKKKRE", "length": 536 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P16662-1", "protein_name": "UDP-glucuronosyltransferase 2B7", "gene_name": "UGT2B7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSVKWTSVILLIQLSFCFSSGNCGKVLVWAAEYSHWMNIKTILDELIQRGHEVTVLASSASILFDPNNSSALKIEIYPTSLTKTELENFIMQQIKRWSDLPKDTFWLYFSQVQEIMSIFGDITRKFCKDVVSNKKFMKKVQESRFDVIFADAIFPCSELLAELFNIPFVYSLSFSPGYTFEKHSGGFIFPPSYVPVVMSELTDQMTFMERVKNMIYVLYFDFWFEIFDMKKWDQFYSEVLGRPTTLSETMGKADVWLIRNSWNFQFPYPLLPNVDFVGGLHCKPAKPLPKEMEDFVQSSGENGVVVFSLGSMVSNMTEERANVIASALAQIPQKVLWRFDGNKPDTLGLNTRLYKWIPQNDLLGHPKTRAFITHGGANGIYEAIYHGIPMVGIPLFADQPDNIAHMKARGAAVRVDFNTMSSTDLLNALKRVINDPSYKENVMKLSRIQHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLTWFQYHSLDVIGFLLVCVATVIFIVTKCCLFCFWKFARKAKKGKND", "length": 529 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P17717-1", "protein_name": "UDP-glucuronosyltransferase 2B17", "gene_name": "Ugt2b17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPGKWISALLLLQISCCFRSVKCGKVLVWPMEFSHWMNIKIILDELVQRGHEVTVLRPSAYYVLDPKKSPGLKFETFPTSVSKDNLENFFIKFVDVWTYEMPRDTCLSYSPLLQNMIDEFSDYFLSLCKDVVSNKELMTKLQESKFDVLLSDPVASCGELIAELLQIPFLYSIRFSPGYQIEKSSGRFLLPPSYVPVILSGLGGQMTFIERIKNMICMLYFDFWFQMFNDKKWDSFYSEYLGRPTTLVETMGQAEMWLIRSNWDLEFPHPTLPNVDYVGGLHCKPAKPLPKDMEEFVQSSGDHGVVVFSLGSMVSNMTEEKANAIAWALAQIPQKVLWKFDGKTPATLGHNTRVYKWLPQNDLLGHPKTKAFVTHGGANGVYEAIYHGIPMIGIPLFGEQHDNIAHMVAKGAAVALNIRTMSKSDVLNALEEVIENPFYKKNAIWLSTIHHDQPMKPLDRAVFWIEFVMRHKRAKHLRPLGHNLTWYQYHSLDVIGFLLSCVATTIVLSVKCLLFIYRFFVKKENKMKNE", "length": 530 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P19224-1", "protein_name": "UDP-glucuronosyltransferase 1A6", "gene_name": "UGT1A6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MACLLRSFQRISAGVFFLALWGMVVGDKLLVVPQDGSHWLSMKDIVEVLSDRGHEIVVVVPEVNLLLKESKYYTRKIYPVPYDQEELKNRYQSFGNNHFAERSFLTAPQTEYRNNMIVIGLYFINCQSLLQDRDTLNFFKESKFDALFTDPALPCGVILAEYLGLPSVYLFRGFPCSLEHTFSRSPDPVSYIPRCYTKFSDHMTFSQRVANFLVNLLEPYLFYCLFSKYEELASAVLKRDVDIITLYQKVSVWLLRYDFVLEYPRPVMPNMVFIGGINCKKRKDLSQEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH", "length": 532 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P20720-1", "protein_name": "UDP-glucuronosyltransferase 1-2", "gene_name": "Ugt1a2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTGLCAPLRGLSGLLLLLCALPWAEGGKVLVFPMEGSHWLSMRDVVRELHARGHQAVVLAPEVTVHMKGEDFFTLQTYAFPYTKEEYQREILGNAKKGFEPQHFVKTFFETMASIKKFFDLYANSCAALLHNKTLIQQLNSSSFDVVLTDPVFPCGALLAKYLQIPAVFFLRSVPCGIDYEATQCPKPSSYIPNLLTMLSDHMTFLQRVKNMLYPLTLKYICHLSITPYESLASELLQREMSLVEVLSHASVWLFRGDFVFDYPRPIMPNMVFIGGINCVIKKPLSQEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTLLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKARAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVYKSCAYGCRKCFGGKGRVKKSHKSKTH", "length": 533 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P22309-1", "protein_name": "UDP-glucuronosyltransferase 1A1", "gene_name": "UGT1A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVESQGGRPLVLGLLLCVLGPVVSHAGKILLIPVDGSHWLSMLGAIQQLQQRGHEIVVLAPDASLYIRDGAFYTLKTYPVPFQREDVKESFVSLGHNVFENDSFLQRVIKTYKKIKKDSAMLLSGCSHLLHNKELMASLAESSFDVMLTDPFLPCSPIVAQYLSLPTVFFLHALPCSLEFEATQCPNPFSYVPRPLSSHSDHMTFLQRVKNMLIAFSQNFLCDVVYSPYATLASEFLQREVTVQDLLSSASVWLFRSDFVKDYPRPIMPNMVFVGGINCLHQNPLSQEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH", "length": 533 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P22310-1", "protein_name": "UDP-glucuronosyltransferase 1A4", "gene_name": "UGT1A4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARGLQVPLPRLATGLLLLLSVQPWAESGKVLVVPTDGSPWLSMREALRELHARGHQAVVLTPEVNMHIKEEKFFTLTAYAVPWTQKEFDRVTLGYTQGFFETEHLLKRYSRSMAIMNNVSLALHRCCVELLHNEALIRHLNATSFDVVLTDPVNLCGAVLAKYLSIPAVFFWRYIPCDLDFKGTQCPNPSSYIPKLLTTNSDHMTFLQRVKNMLYPLALSYICHTFSAPYASLASELFQREVSVVDLVSYASVWLFRGDFVMDYPRPIMPNMVFIGGINCANGKPLSQEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH", "length": 534 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P35503-1", "protein_name": "UDP-glucuronosyltransferase 1A3", "gene_name": "UGT1A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATGLQVPLPWLATGLLLLLSVQPWAESGKVLVVPIDGSHWLSMREVLRELHARGHQAVVLTPEVNMHIKEENFFTLTTYAISWTQDEFDRHVLGHTQLYFETEHFLKKFFRSMAMLNNMSLVYHRSCVELLHNEALIRHLNATSFDVVLTDPVNLCAAVLAKYLSIPTVFFLRNIPCDLDFKGTQCPNPSSYIPRLLTTNSDHMTFMQRVKNMLYPLALSYICHAFSAPYASLASELFQREVSVVDILSHASVWLFRGDFVMDYPRPIMPNMVFIGGINCANRKPLSQEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH", "length": 534 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P35504-1", "protein_name": "UDP-glucuronosyltransferase 1A5", "gene_name": "UGT1A5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATGLQVPLPQLATGLLLLLSVQPWAESGKVLVVPTDGSHWLSMREALRDLHARGHQVVVLTLEVNMYIKEENFFTLTTYAISWTQDEFDRLLLGHTQSFFETEHLLMKFSRRMAIMNNMSLIIHRSCVELLHNEALIRHLHATSFDVVLTDPFHLCAAVLAKYLSIPAVFFLRNIPCDLDFKGTQCPNPSSYIPRLLTTNSDHMTFLQRVKNMLYPLALSYLCHAVSAPYASLASELFQREVSVVDLVSHASVWLFRGDFVMDYPRPIMPNMVFIGGINCANGKPLSQEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH", "length": 534 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P36510-1", "protein_name": "UDP-glucuronosyltransferase 2A1", "gene_name": "Ugt2a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLKNILLWSLQLSLLGMSLGGNVLIWPMEGSHWLNVKIIIDELLRKEHNVTVLVASGALFITPSVSPSLTFEIYPVPFGKEKIESVIKDFVLTWLENRPSPSTIWTFYKEMAKVIEEFHLVSRGICDGVLKNEKLMTKLQRGKFEVLLSDPVFPCGDIVALKLGIPFIYSLRFSPASTVEKHCGKVPFPPSYVPAILSELTDQMSFADRVRNFISYRMQDYMFETLWKQWDSYYSKALGRPTTLCETMGKAEIWLMRTYWDFEFPRPYLPNFEFVGGLHCKPAKPLPKEMEEFVQTSGEHGVVVFSLGSMVKNLTEEKANLIASALAQIPQKVLWRYKGKIPATLGSNTRLFDWIPQNDLLGHPKTRAFITHGGTNGIYEAIYHGIPMVGVPMFADQPDNIAHMKAKGAAVEVNMNTMTSADLLSAVRAVINEPFYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSLDVIGFLLACMASAILLVIKCCLFVFQKIGKTXKKNKRD", "length": 527 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" }, { "id": "FB:FBgn0026755", "url": "https://alliancegenome.org/gene/FB:FBgn0026755#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P36511-1", "protein_name": "UDP-glucuronosyltransferase 2B15", "gene_name": "Ugt2b15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGKWISALLLLQISFCFKSGNCGKVLVWPMEYSHWMNIKIILEELVQKGHEVTVLRPSAFVFLDPKETSDLKFVTFPTSFSSHDLENFFTRFVNVWTYELPRDTCLSYFLYLQDTIDEYSDYCLTVCKEAVSNKQFMTKLQESKFDVVFSDAIGPCGELIAELLQIPFLYSLRFSPGYTIEQYIGGVLFPPSYVPMIFSGLAGQMTFIERVHNMICMLYFDFWFQTFREKKWDPFYSKTLGRPTTLAEIMGKAEMWLIRSYWDLEFPHPISPNVDYIGGLHCKPAKPLPKDIEDFVQSSGEHGVVVFSLGSMVRNMTEEKANIIAWALAQIPQKVLWRFDGKKPPTLGPNTRLYKWLPQNDLLGHPKTKAFVTHGGANGIYEAIHHGIPMIGIPLFAEQHDNIAHMVAKGAAVEVNFRTMSKSDLLNALEEVIDNPFYKKNAMWLSTIHHDQPTKPLDRAVFWIEFVMRHKGAKHLRSLGHNLPWYQYHSLDVIGFLLSCVAVTVVLALKCFLFVYRFFVKKEKKTKNE", "length": 530 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P36537-1", "protein_name": "UDP-glucuronosyltransferase 2B10", "gene_name": "UGT2B10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALKWTTVLLIQLSFYFSSGSCGKVLVWAAEYSLWMNMKTILKELVQRGHEVTVLASSASILFDPNDSSTLKLEVYPTSLTKTEFENIIMQLVKRLSEIQKDTFWLPFSQEQEILWAINDIIRNFCKDVVSNKKLMKKLQESRFDIVFADAYLPCGELLAELFNIPFVYSHSFSPGYSFERHSGGFIFPPSYVPVVMSKLSDQMTFMERVKNMLYVLYFDFWFQIFNMKKWDQFYSEVLGRPTTLSETMRKADIWLMRNSWNFKFPHPFLPNVDFVGGLHCKPAKPLPKEMEEFVQSSGENGVVVFSLGSMVSNMTEERANVIATALAKIPQKVLWRFDGNKPDALGLNTRLYKWIPQNDLLGHPKTRAFITHGGANGIYEAIYHGIPMVGIPLFFDQPDNIAHMKAKGAAVRVDFNTMSSTDLLNALKTVINDPSYKENIMKLSRIQHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHNLTWFQYHSLDVIGFLLACVATVLFIITKCCLFCFWKFARKGKKGKRD", "length": 528 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P54855-1", "protein_name": "UDP-glucuronosyltransferase 2B15", "gene_name": "UGT2B15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLKWTSVFLLIQLSCYFSSGSCGKVLVWPTEYSHWINMKTILEELVQRGHEVTVLTSSASTLVNASKSSAIKLEVYPTSLTKNYLEDSLLKILDRWIYGVSKNTFWSYFSQLQELCWEYYDYSNKLCKDAVLNKKLMMKLQESKFDVILADALNPCGELLAELFNIPFLYSLRFSVGYTFEKNGGGFLFPPSYVPVVMSELSDQMIFMERIKNMIHMLYFDFWFQIYDLKKWDQFYSEVLGRPTTLFETMGKAEMWLIRTYWDFEFPRPFLPNVDFVGGLHCKPAKPLPKEMEEFVQSSGENGIVVFSLGSMISNMSEESANMIASALAQIPQKVLWRFDGKKPNTLGSNTRLYKWLPQNDLLGHPKTKAFITHGGTNGIYEAIYHGIPMVGIPLFADQHDNIAHMKAKGAALSVDIRTMSSRDLLNALKSVINDPVYKENVMKLSRIHHDQPMKPLDRAVFWIEFVMRHKGAKHLRVAAHNLTWIQYHSLDVIAFLLACVATVIFIITKFCLFCFRKLAKKGKKKKRD", "length": 530 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P70691-1", "protein_name": "UDP-glucuronosyltransferase 1-2", "gene_name": "Ugt1a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTGLCVPLRGISGLLLLLCALPWAEGAKVLVLPMEGSQWLSMRDVVRELHARGHQTVVLASEVTVHIKGEDFFTLKTYAFPYTKEEYQQEILSDIEKTFKTQHFVKAFFETTASIRNFFDLYSNSCIALLHNKMLIQQLNSSFFDVILTDPIFPCGAVLAKYLQIPAVFILRSLSCGIEYEATQCPNPSSYIPNLLTRLSDHMDFLQRVQNMLYYLVLKYICRLSITPYESLASELLQREVSLVEVLSHASVWLFRGDFVLDYPRPIMPNMVFIGGINCVTKKPLSQEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVFKCCAYGCRKCFGGKGRVKKSHKSKTH", "length": 533 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q62452-1", "protein_name": "UDP-glucuronosyltransferase 1A9", "gene_name": "Ugt1a9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPVAFPTSFFLCLLLASGLAQAGRLLVVPMDGSHWFTMQMVVEKLIHRGHEVVVVIPEVSWQLGKSLNCTVKTYSISHTLEDLDREFKYLSYTQWKTPEHSIRSFLTGSARGFFELTFSHCRSLFNDKKLVEYLKQRFFDAVFLDPFDVCGLIVAKYFSLPSVIFARGVFCDYLEEGAQCPSLPSYVPRLFSKYTDTMTFKERVWNHLIYIEEHAFCSYFLRTAVEVASEILQTPVTMTDLFSPVSIWLLRTDFVLEFPRPVMPNMVFIGGINCLQKKSLSKEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVFKCCAYGCRKCFGGKGRVKKSHKSKTH", "length": 528 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q63886-1", "protein_name": "UDP-glucuronosyltransferase 1A1", "gene_name": "Ugt1a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTVVCWSSRLLLLLPYLLLCVFGPSASHAGRLLVFPMDGSHWLSMLGVIQQLQQKGHEVVVIAPEASIHIKEGSFYTLRKFPVPFQKENVTATLVELGRTAFNQDSFLLRVVKIYMKVKRDSSMLLAGCSHLLHNAEFMASLEESHFDALLTDPFLPCGSIVAQYLTVPTVYFLNKLPCSLDSEATQCPVPLSYVPKSLSFNSDRMNFLQRVKNVLLAVSENFMCRVVYSPYGSLATEILQKEVTVQDLLSPASIWLMRSDFVKDYPRPIMPNMVFIGGINCLQKKPLSQEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVFKCCAYGCRKCFGGKGRVKKSHKSKTH", "length": 535 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q64435-1", "protein_name": "UDP-glucuronosyltransferase 1A6", "gene_name": "Ugt1a6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MACLLPAAQTLPAGFLFLVLWASVLGDKLLVVPQDGSHWLSMKEIVEHLSERGHDIMVLVPEVNLLLGESKYYRRKIFSVTYSLEELQTRFRTFGNNHFLPGASLMGPLREYRNNMIVVDMFFSNCQSLLKDSATLSFLRENKFDALFTDPAMPCGVILAEYLNLPSVYLFRGFPCSLEHMLGQSPSPVSYVPRFYTKFSDHMTFPQRLANFIVNILENYLYYCLYSKYEIIASDLLKRDVSLPSLHQNSLWLLRYDFVFEYPRPVMPNMIFLGGINCKKKGKLTQEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVFKCCAYGCRKCFGGKGRVKKSHKSKTH", "length": 531 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q64550-1", "protein_name": "UDP-glucuronosyltransferase 1A1", "gene_name": "Ugt1a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVVCRSSCSLLLLPCLLLCVLGPSASHAGKLLVIPIDGSHWLSMLGVIQQLQQKGHEVVVIAPEASIHIKEGSFYTMRKYPVPFQNENVTAAFVELGRSVFDQDPFLLRVVKTYNKVKRDSSMLLSGCSHLLHNAEFMASLEQSHFDALLTDPFLPCGSIVAQYLSLPAVYFLNALPCSLDLEATQCPAPLSYVPKSLSSNTDRMNFLQRVKNMIIALTENFLCRVVYSPYGSLATEILQKEVTVKDLLSPASIWLMRNDFVKDYPRPIMPNMVFIGGINCLQKKALSQEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKARAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVYKSCAYGCRKCFGGKGRVKKSHKSKTH", "length": 535 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q64633-1", "protein_name": "UDP-glucuronosyltransferase 1A7", "gene_name": "Ugt1a7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPADVPASLPLGLCLLLASGFGHAGKLLVVPMDGSHWFTMQMVVEKLLPKGHEVVVVVPEVSWQLGKPLNFTVKTYSVSHTQEDLNREFKFFIDSQWKTQQESGVLPLLTSPAQGFFELLFSHCRSLFKDKKLVEYLKQSSFDAVFLDPFDVCGLTVAKYFSLPSVVFSRGIFCHYLEEGSQCPSPPSYVPRPILKLTDTMTFKERVWNLLSYMGEHAFCPSFFKTATDIASEVLQTPVTMTDLFSPVSVWLLRTDFTLELPRPVMPNVIHIGGINCHQRKPVSKEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTLLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKARAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVYKSCAYGCRKCFGGKGRVKKSHKSKTH", "length": 531 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q64634-1", "protein_name": "UDP-glucuronosyltransferase 1A8", "gene_name": "Ugt1a8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPSGCPPSLPLCVCLFLASGFAQAGRLLVVPMDGSHWFTMQMIVEKLSHRGHEVVVVIPEVSWHMGKSLNFTVKLLLVLNTLEDLNYHFKFFAHNQWKTQEVGMFSLLKHSGKGFFELLFSHCRSLFKDKKLVEYLKQSSFDAVFLDPFDVCGLILAKYFSLPSVVFSGGIFCHYLDEGAQCPSPPSYVPRILSKFTDTMTFKERVWNHLSYMKERAFCPYFFKTAVEIASEVLQTPVTMRDLFSPVSIWMFRTDFVLEFPRPMMPNMVYIGGINCHQGKPLSKEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTLLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKARAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVYKSCAYGCRKCFGGKGRVKKSHKSKTH", "length": 530 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q64637-1", "protein_name": "UDP-glucuronosyltransferase 1A3", "gene_name": "Ugt1a3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGIQGFLQKLSGLLLLLCALPWAEGGKVLVFPMEGSHWLSIRDVVRELHARGHQAVVLAPEVTVHIKEEDFFTLQTYPVPYTKEEYRHHLLGHLQNFFETEFSLKLVLQTMAAVNNVSTFYVRSCRGLLHNTALIQSLNSSSFDVVLTDPFFPCGAVLAMYLRVPAVFFLQSMLCELEFEATNSPNPSSYIPRLLTLNSDHMSFLDRVKNMLYPVPWMYLCHVNYGSLARLASDLLQREVSVVEILRHASVWLLRKDFVFHYPRPFMPNMVFIGGINCANRKPLSQEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTLLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKARAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVYKSCAYGCRKCFGGKGRVKKSHKSKTH", "length": 531 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q64638-1", "protein_name": "UDP-glucuronosyltransferase 1A5", "gene_name": "Ugt1a5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLHVTLQGLAGLLLLLYALPWAEGGKVLVFPMEGSHWLSMRDVVRELHARGHQAVVLAPEVTVHIKEEDFFTLQTYPVPYTRQGFRQQMMRNIKVVFETGNYVKTFLETSEILKNISTVLLRSCMNLLHNGSLLQHLNSSSFDMVLTDPVIPCGQVLAKYLGIPTVFFLRYIPCGIDSEATQCPKPSSYIPNLLTMLSDHMTFLQRVKNMLYPLALKYICHFSFTRYESLASELLQREVSLVEVLSHASVWLFRGDFVFDYPRPVMPNMVFIGGINCVIKKPLSQEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTLLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKARAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVYKSCAYGCRKCFGGKGRVKKSHKSKTH", "length": 531 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6PDD0-1", "protein_name": "UDP-glucuronosyltransferase 2A2", "gene_name": "Ugt2a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIKKVLQLLIFHLTLAEIVLSGNVVVWPTDGSHWLNIKILLEELVQRNHSVTVLAPSETLFINSRLDAFINFEEIPVSYTKSKIDEIIEHMIALWLDHRPTPLTMWTFYKELGNLLATFYTTNKQMCDGVLNNPTVMERLQKGGFDVLLADPVTMCGELVALKLGIPFVYTLRFSPAFTVERHCGKIPAPISYVPAALSELTDQMSFGERVKNIISYSLQDYIFKTYWGEWNSYYSKVLGRPTTLCETMGKAEIWLMRTYWDFEFPRPYLPNFEFVGGLHCKPAKPLPKEMEEFVQTSGEHGIVVFSLGSMVKNLTDEKANLIASALAQIPQKVLWRYKGKIPDTLGSNTRLFDWIPQNDLLGHPKTRAFITHGGTNGIYEAIYHGIPMVGVPMFADQPDNIAHMKAKGAAVEVNMNTMTSSDLLNALRTVINEPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSLDVIGFLLACVASAILLVAKCCLFIFQKVGKTGKKKKRD", "length": 528 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "FB:FBgn0026755", "url": "https://alliancegenome.org/gene/FB:FBgn0026755#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6UWM9-1", "protein_name": "UDP-glucuronosyltransferase 2A3", "gene_name": "UGT2A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRSDKSALVFLLLQLFCVGCGFCGKVLVWPCDMSHWLNVKVILEELIVRGHEVTVLTHSKPSLIDYRKPSALKFEVVHMPQDRTEENEIFVDLALNVLPGLSTWQSVIKLNDFFVEIRGTLKMMCESFIYNQTLMKKLQETNYDVMLIDPVIPCGDLMAELLAVPFVLTLRISVGGNMERSCGKLPAPLSYVPVPMTGLTDRMTFLERVKNSMLSVLFHFWIQDYDYHFWEEFYSKALGRPTTLCETVGKAEIWLIRTYWDFEFPQPYQPNFEFVGGLHCKPAKALPKEMENFVQSSGEDGIVVFSLGSLFQNVTEEKANIIASALAQIPQKVLWRYKGKKPSTLGANTRLYDWIPQNDLLGHPKTKAFITHGGMNGIYEAIYHGVPMVGVPIFGDQLDNIAHMKAKGAAVEINFKTMTSEDLLRALRTVITDSSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRSAAHDLTWFQHYSIDVIGFLLACVATAIFLFTKCFLFSCQKFNKTRKIEKRE", "length": 527 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6ZQM8-1", "protein_name": "UDP-glucuronosyltransferase 1A7", "gene_name": "Ugt1a7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPADFPASLPLCVCLLLASGLAQAGRLLVVPMDGSHWFTMQTVVEKLLHKGHEVVVVVPEVSWQLTKPLNFVVKTYAVSHTQEDLNREFKIFIDAQWKSQQEGGILPLLDSPAKGFFELLFSHCRSLFNDKKLVEYLKQTSFDAVFLDPFDVCGLTVAKYFSLPSVVFSRGIFCHYLEDAAQCPSPPSYIPRMLLKFTDTMTFKERTRNLLAYMGERAFCHKFFKSAADIASEVLQTPVTMTDLFSPVSIWLLRTDFVLEFPRPVMPNVIYIGGINCHQGKPLSKEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVFKCCAYGCRKCFGGKGRVKKSHKSKTH", "length": 531 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80X89-1", "protein_name": "UDP-glucuronosyltransferase 2A1", "gene_name": "Ugt2a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLKNILLCSLQISLLGMSLGGNVLIWPMEGSHWLNVKIIIDELLRKEHNVTVLVASGALFITPSSISPSLTFEIYPVPFGKEKIESVIKDFVLTWLENRPSPSTIWTFYKEMAKVIEEFHLVSRGICDGVLKNEKLMSKLQKEKFEVLLSDPVFPCGDIVALKLGIPFIYSLRFSPASTVEKHCGKVPFPPSYVPAILSELTDQMSFTDRVRNFISYRMQDYMFETLWKQWDSYYTKALGRPTTLCETMGKAEIWLMRTYWDFEFPRPYLPNFEFVGGLHCKPAKPLPKEMEEFVQTSGEHGIVVFSLGSMVKNLTDEKANLIASALAQIPQKVLWRYKGKIPDTLGSNTRLFDWIPQNDLLGHPKTRAFITHGGTNGIYEAIYHGIPMVGVPMFADQPDNIAHMKAKGAAVEVNMNTMTSSDLLNALRTVINEPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSLDVIGFLLACVASAILLVAKCCLFIFQKVGKTGKKKKRD", "length": 528 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" }, { "id": "FB:FBgn0026755", "url": "https://alliancegenome.org/gene/FB:FBgn0026755#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8BWQ1-1", "protein_name": "UDP-glucuronosyltransferase 2A3", "gene_name": "Ugt2a3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVSEKCVAAFFLLQLCWAGCGFCSKVLVWPCDMSHWLNLKTILEELGARGHEVTVLKYPSIIIDQSKRIPLHFENIPLLYEIETAENRLNEIANLAVNVIPNLSLWEAAKTLQDFFLQVTGDFESICRSVLYNQKFMDKLRDAQYDVVVIDPVVPCGELVAEVLQIPFVYTLRFSMGYYMEKHCGQLPIPLSYVPVVMSELTDNMTFTERVKNMMFSLLFEYWLQQYDFAFWDQFYSETLGRPTTFCKTVGKADIWLIRTYWDVEFPRPYLPNFEFVGGLHCKPAKPLPKEMEEFVQSSGEHGVVVFSLGSMVKNLTEEKANLIASVLAQIPQKVLWRYSGKKPATLGSNTRLFNWIPQNDLLGHPKTKAFITHGGTNGIYEAIYHGVPMVGVPMLGDQPHNIAHMEAKGAALKVSISTMTSTDLLSAVRAVINEPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSLDVIGFLLLCVVTLTFIITKFCLFVCQKLYMKESKKMGNRKKKN", "length": 534 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "FB:FBgn0026755", "url": "https://alliancegenome.org/gene/FB:FBgn0026755#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BY64-1", "protein_name": "UDP-glucuronosyltransferase 2B28", "gene_name": "UGT2B28", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALKWTSVLLLIHLGCYFSSGSCGKVLVWTGEYSHWMNMKTILKELVQRGHEVTVLASSASILFDPNDAFTLKLEVYPTSLTKTEFENIIMQQVKRWSDIQKDSFWLYFSQEQEILWEFHDIFRNFCKDVVSNKKVMKKLQESRFDIIFADAFFPCGELLAALLNIPFVYSLCFTPGYTIERHSGGLIFPPSYIPVVMSKLSDQMTFMERVKNMIYVLYFDFWFQMCDMKKWDQFYSEVLGRPTTLFETMGKADIWLMRNSWSFQFPHPFLPNIDFVGGLHCKPAKPLPKEMEEFVQSSGENGVVVFSLGSVISNMTAERANVIATALAKIPQKVLWRFDGNKPDALGLNTRLYKWIPQNDLLGLPKTRAFITHGGANGIYEAIYHGIPMVGIPLFWDQPDNIAHMKAKGAAVRLDFHTMSSTDLLNALKTVINDPSYKENVMKLSIIQHDQPVKPLHRAVFWIEFVMCHKGAKHLRVAARDLTWFQYHSLDVIGFLLACVATVIFVVTKFCLFCFWKFARKGKKGKRD", "length": 529 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9HAW7-1", "protein_name": "UDP-glucuronosyltransferase 1A7", "gene_name": "UGT1A7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARAGWTGLLPLYVCLLLTCGFAKAGKLLVVPMDGSHWFTMQSVVEKLILRGHEVVVVMPEVSWQLGRSLNCTVKTYSTSYTLEDQDREFMVFADARWTAPLRSAFSLLTSSSNGIFDLFFSNCRSLFNDRKLVEYLKESCFDAVFLDPFDACGLIVAKYFSLPSVVFARGIFCHYLEEGAQCPAPLSYVPRLLLGFSDAMTFKERVWNHIMHLEEHLFCPYFFKNVLEIASEILQTPVTAYDLYSHTSIWLLRTDFVLEYPKPVMPNMIFIGGINCHQGKPVPMEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH", "length": 530 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9HAW8-1", "protein_name": "UDP-glucuronosyltransferase 1A10", "gene_name": "UGT1A10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARAGWTSPVPLCVCLLLTCGFAEAGKLLVVPMDGSHWFTMQSVVEKLILRGHEVVVVMPEVSWQLERSLNCTVKTYSTSYTLEDQNREFMVFAHAQWKAQAQSIFSLLMSSSSGFLDLFFSHCRSLFNDRKLVEYLKESSFDAVFLDPFDTCGLIVAKYFSLPSVVFTRGIFCHHLEEGAQCPAPLSYVPNDLLGFSDAMTFKERVWNHIVHLEDHLFCQYLFRNALEIASEILQTPVTAYDLYSHTSIWLLRTDFVLDYPKPVMPNMIFIGGINCHQGKPLPMEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH", "length": 530 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9HAW9-1", "protein_name": "UDP-glucuronosyltransferase 1A8", "gene_name": "UGT1A8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARTGWTSPIPLCVSLLLTCGFAEAGKLLVVPMDGSHWFTMQSVVEKLILRGHEVVVVMPEVSWQLGKSLNCTVKTYSTSYTLEDLDREFMDFADAQWKAQVRSLFSLFLSSSNGFFNLFFSHCRSLFNDRKLVEYLKESSFDAVFLDPFDACGLIVAKYFSLPSVVFARGIACHYLEEGAQCPAPLSYVPRILLGFSDAMTFKERVRNHIMHLEEHLFCQYFSKNALEIASEILQTPVTAYDLYSHTSIWLLRTDFVLDYPKPVMPNMIFIGGINCHQGKPLPMEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH", "length": 530 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9V9X9-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt35D1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPPIFLLVCLLPGYSEGARILAVFPLPSSSHYFFALPYLKSLASLGHEITSVSPYPQREPFRNIHDIPVPEVFENFNEVLRIASTPRSTWQSSDFINEYVLNLTKTVLNNEGVRRDILGPQKPHFDLVIMDLWRMDVLSGLAAYFDAPIIGMASYGTDWKIDELMGNVSPISYLQSPSSRFYDLEAYGERLLHLMERTFSYMNYKWRHVRKQETLYSQFFPSVAERKPLSEISRNFDLVLVNQHFTLGPPRPYVPNMIQVGGLHVDHSTEALSAELDHFIQGAGESGVIYFSLGTNVKSKSLSEDRRKVLLETFASLPQRIVWKFEDELLPGKPPNVFISKWFPQQAILAHPNVKLFITHGGLLSTIESIHHGKPMLGLPCLFDQFRNMDHVRQVGLGLVLNIKQMTSEEFRSTIIRLLTNKSFEETARITAARYRDQPMKPMETAIWWTEYVLSHKGAAHMQVAGKDLGFVRYHSLDVFGTFLVGALVILGIVTYLLVMTLRKCLFLIKRGKCEAIKKIQ", "length": 521 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VCL3-1", "protein_name": "UDP-glycosyltransferase family 303 member B2", "gene_name": "Ugt303B2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRLGYAWLAFGLLLHLNLYLELGQAANILGVFPYRIPSPFQMVRPLIKALVERGHKVTMVTPADYPAKIDGVRHIRVPMLNQLMQNLMKNDQFFDALGDKWREGVLVSTIFYNVSHAILNNNGVQMLMRDKSIRFDMIMVEASHLDALYGLAEFYNATLLGISCMHMTWHIDYLAGNLAPSVYEPISPNGFALDNTFLSRWSNWIYITEEKLLERLVFRPAQVRLFKKFFGYPAEKLDELRARFSVILVNSHFSMGRVRANVPNIIEVAGVHLSEPPEPCGAELQKYLDEAEHGAIYFSMGQDILIKYLPENMQKQLLLVFLQMKQRVIWKSELSMLANKSENIYVMDKVPQRMVLAHPNLRLFITHGGLQSVMEAIDNGVPMLGLPLFFDQFNNIHRVQLAGMAKVLDPNDLNADTLIETIKELLENPSYAQRAKEMAASFRDRPMSPLDTAIWWTEYALRNRDTSHMRLNVEEIPLMRYYRLDSILTFGVRLGCVCGSLIFLGWRLYQKNRNRHTRLQERERVIAQIQLGLSNYEVVS", "length": 540 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VCL4-1", "protein_name": "UDP-glycosyltransferase family 303 member B1, isoform A", "gene_name": "Ugt303B1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRLRYCWLTLSLCLLLQHDRAQAANILGIFPYRHISPFFVMQPLVRTLATRGHNVTLITPIGMPNDIEGVRHIRVAQLNERIKEMLESDQVLDFMINKWTESALTAKALFNASNDILSDPGVQRMLHDKSESFDLIIMEPSSLDALYGLVEFYNATLMGLSSIRINWHTYELAGNPAPSIYEPISPVGFSLETSLFSRVYNWIHIMEEKLVNYLILRPAQLHLFQKFFGYSAQKMNELRSRFSLMLINSHYSMGKVRANAPNIIEVGGLHLSEPPEPSDEELQKFLDKADHGVIYFSMGNDILIKFLPENIQELLLQTFATLNESIIWKSELLYMPDKSDNVYVVEQAPQRHILNHPNVRLFITNGGLLSVIEAVDSGVPMLGLPMFFDQFGNMRWVQLSGMAEVMDINSLNKDTLTETIKHMLANNSYYLKAKEISQFFKDRPMSPLDTAVWWTEYALRNRNITRMRLNLEEIPLIEYYRIDSILAFSLRFGLVAASLIFLVYTLFLKYRIRLRRLHP", "length": 519 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VCL5-1", "protein_name": "UDP-glycosyltransferase family 303 member B3", "gene_name": "Ugt303B3", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MHLEFYWLAVLFCLFLQKDLYQDSVQAANILGIFSYHFSSHNLVVRPLAKALVKRGHNVTLITPVGMPTDIEGVRHIRVPKLNQRVQEMIEGDQILDFFGSKWIASLMVVSMLYNMSSDILSDKGVQKMLQNRNERFDLVMLEPSALEALYGVVEHYNATLMGFSGGNVNWSTEEVAGNFAPSINDPISSLGYSRSNSLLSKIYNWVHITEEKLLKHLIFRPSQLRIFKKFFNFSEQKFYNMREKYSVILVNNHISMGRVRSNVPNIIEVGGLHLTEPAEPCDSKLQKFMDDAEHGVIYFSMGQEIMVQFLPEDMQQNLMKSLDQFKQRVVWKTELYNMPNKSDNVYVIEQPPQRAVLAHPNTRLFITNGGLLSVMEAVYSGVPILGLPVFFDQFINLRNVNLRGMAEVLDANEMTLEILTSTIRKLLENPRYALKAKKMSQSFRDRPMSPLDTAVWWTEYALRNKDASHMRLNTEDVPLYYEWDWGLLLGLRFGIVFGSVIYLVYKLFQKTSARRRPFQVTGTVSQHPSLLDRRSQTQ", "length": 539 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VDA5-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt49B2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MILFMKLLFVCLLGTGDGARILAPFFLPVKSHFMMTDAIIRELVKRGHEVTFITPLSLAKENLGPNYREILLPKYDTWADISAMMKTKSALDMIDMSKLTHMRLAQHIGIKSTDFALAHPEVQELIYAKDKKGKFDLLLVEQFHNEGALMLGYIYEIPAITIATFAYANYFSQVFGFVNPLSYVPNVFLSCTDRMSLWERLENVVISTAEDVVREVSYYPQQDAVIRKHFSSLLPRVPTVKQLEQNISVILLNSYMPLTSPRPMSQNMISVGGLHILPPKPLPEHIKNYLDNAEHGAIYFSLGSQVRSADMPAEKLQIFLDVFASLKQRVLWKFEDDQLPNLPDNVKVEKWLPQADILAHPNVKVFIAHGGLFGMQEAVYHAVPVLGMPFYFDQDINIKAGQAAGYAIGLDYRTISKDQLKSALHALLKDPKYQANMMKASRIFRDRPLGAMDTAMYWINYVVEHRGAPHLVAAGVHLPWYQFYLLDVSAIILAITLLPLLTLYAVSRNYKSFRGIRAQKKEAKTE", "length": 526 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VG29-1", "protein_name": "UDP-glycosyltransferase family 37 member A3", "gene_name": "Ugt37A3", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVLRVEKFLLLAIAIGAVMGSSQGANILGLFPSLSPSHLIIQMSAAKVLAENGHNVTVVTVLKPVVNHKNITVIQVPLSKEEAQQMSDTIGAMSKNDNSNMALSLLRMSDQMDFMIRKNAETLMNDRVRDLYLNRGNKFDLVISGYFMNDFQLGFARKVNAPVIVLATMPPNHLLNPLIGNPLEVSYAGISNPAEGSKAVTFQRRLSSYMQSLGFGVFSHLSERRNRNWYKEVYGNDPKMPEYSEMLKNTSLVFFSSHAASEGPIRPNVPSAIEIGGIQIKDKPDPLPQNIAEFLGNATDGAILLSLGSNVQGKHLNPDTVAKMFNVLSKLKERVIWKWEDQENTPGKSANILYSKWLPQDDILAHPNIKLFINHAGKGGITESQYHGKPMLSLPVFADQPRNANAMVKSGFGLTLSLLTLEEKPFQEAILEILSNPQYAERVKSFSTLYRDRPMTARESFLYWTEYVIRHHGAAHLQSPLVHMSFIAANNIDICFLIFVILVSVLVLIKFLVQFIYRRFISKPKKEKTH", "length": 530 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VG30-1", "protein_name": "UDP-glycosyltransferase family 37 member A2", "gene_name": "Ugt37A2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVHKSGIYLLLATAICVLGGCHGANILGVFTSLSPSHLIIQMSTAKVLAERGHNVTVITVLKPVVNHKNITVIMVPLTKEESQQMSDTIGAMSKTDNSNMILSMLRMMGQMEFMFDKMAGALKDDRVRDLYLNRDNKFDLVLSGYFMNVYQLGFAKKVKAPVIVVATMPPNQLLNPLIGNPLEIAYVPSISDSVEKGKGMSFRQRLAGYSSSFFFGIFDFVTQRRSKRLYKELFGDDPNMPEYSELVKNTSLIFFASHAPSEGPIRPNVPAAIEIGGIQVKDTPDPLPQNMAEFLGNATDGAILLSLGSNVKGSHINPDTVVKMFNVLSKLKQRVIWKWEDLEKTPGKSDNIFYSKWLPQDDILAHPNIKLFINHAGKGGITEAQYHGKPMLSLPVFGDQPGNADVMVKQGFGLTQSLLSLEEQPFKEAILEILSNPQYFDKVASFSSLYRDRPMSARESVIYWTEYVIRHHGAAHLQSPLVHMSFIAANNIDIYALIAVVLVILVLLLKLLLQFIYRKIFAKPKKEKKH", "length": 530 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VGS7-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt303A1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFSGPGIAGLLLTVLLFGLLCPKLTNAENILAVFSYTFGSSYLLITPFLRNLVQRGHQLTLISAVTIMPHIEGVHHIRVPKLDMLMKILLDFEYDTDLTKWTEAQFLSEYFYNCSKFVLEDPGVQELLRNASAKYSLIILEASHNDALYGFSQHFNAPLLGVAAYGSSWNIDFLVGNSAPSVYEPMSALGYTSGLNLIEKWHNLIYITEERLVERFIYLPRQIDLYKQHFPGATTSIHDLRRRFSLVLINQHFTMGRVRSNVPNIVEVAGMHLDEKPYPLDAELKKILDEAEHGVIYFSMGLQLLDHWLPPGMRASMSDAFAQLKQQVIWKTDYPEMVNQSRNVFARTWFPQRAILNHPNVKLFITHAGLLSLIESVHYAVPLLCIPLFYDQFQNTKRMEKLGVARKLDFKNLFRDEIVLAIEDLVYNASYKRNARDLSQRFHDQPMSAMDTAIWWTEYILRHKGADHMRIAEQEMSLMQYYNVDVVSVLFGRIGLSAIIVIFLGWKLVSLATRHLEYRLNVPMVR", "length": 526 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VGS8-1", "protein_name": "UDP-glycosyltransferase family 304 member A1", "gene_name": "Ugt304A1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFPPGRWLLPMFWLISNSICWIRSSRILVIAPFESHSQCMLVTPYIQALKDRGHQLTVIHAYKHCMHKIEDVTFIRIWYNNNVFLEFEESVGIASANNKWEEISSMSSLMANATLNVLNNVEVRALMKSRITFDAVVLEAGYSDVLYGMAAHFSAQLIGICTCVADWNINNLVGFSTSTLTEPIMPFRAKYVKNVWDRIYNWLYTTEEWLLINLVFLPKQRLIHDHFFGHLEKSFHEIRQDFALMLLNQHFSLFRARPNVPGMVEVAGLHIPKEDPQLPSDLQVFIDEAEHGVILFSLGLEQDSKDLPRKTQEILVETFKSVPQRVIWKFDGESTMSLGTDIYHSKLLPQQAILAHPNVKLFISHCGMMSVIEAAYYAKPVLGLPSFFDQFRNLEIMKEEGVALELNINSLTVKELKDAIHSMINEPEYRESALAISQRFRDQPIHPLDAAIYWTEYIIRYKGADHMKISQSQLKLFDYYSLDNFIMVGSRLSLVVALVFLVLSKSRRWLNHLSTSAKSFLPTKHLIRS", "length": 529 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VGS9-1", "protein_name": "UDP-glycosyltransferase family 35 member A1", "gene_name": "Ugt35A1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGGIFSVTGLGILLIGLIWLFAANADEGVQSSRILAVFPFPGRSQYIFAEQFMKELAHRGHNVTVINTFGSDKNEPNFRVIGAKKIHEIMAAFGNADYTQTASQWQMLTMTTQFLNLLTTSILDDAAVKDLLNSGEKFDLVIMEAVQTEALFGLIQHFGAETIGISSYGTDTHIDELMGNISPLSYNPLLLSSRTEQMDFKDRVMNVFEASVMWLHKRIVHLPSQRDLYAKYFPTARKSLDEVLDSFALMLLGQHFSLSYPRPYLPNMIEVGGLHLQQKRKVQPLAKELSEFVEQSEKGVIYFSMGSNIKSKDLPPSTRKMLMQTFASVPQRVLWKFEDDQLPEKPDNVFISKWFPQPDILAHPNVKLFITHGGLLSTIESIYFGKPILGLPIFYDQHLNVQRAKQVGYGLSADIWSVNATELTPLIQELLSNPSYAAAAQTKSKLFRDQKETALERAIWWTEYVLRHKGAKHLRCASRDLDFIQFHGLDTWGLLIAITFVSLLIVVILIKCLQRVFVSLISKIRKNRAEASKLKTQ", "length": 537 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VGT0-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt35B1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLALRIGFLLLTLPASMQAARILAIFPFPGPSQYINVVPYLKELANRGHQVTSVNAFPQKKPVVNFRDVFIPDVFNNYKELINELSGPMNLWQENNFINKFFVSVTRCVLTNKEVTETLLPPGKDHFDLIIVEALRSDAYYGFAAHFNAPIIGISTFGTDWNIDALVGNESPLSYTPLATGGLTDRMTFLERLSNFVDTTVAWLNYRFVHMSEQEKMYAKYFPEASKRVQLTDLNRNFSLVLLNQHFSLSFPRPYVPNMIEVGGLHISHKPAPLPKDLEEFIQGSGEHGVIYFSLGSNVLSKDLPADRKDLILKTFASLPQRVLWKFEDDKLPGKPSNVFISKWFPQPDILAHPKVKLFITHGGLLSTIESIHHGKPVLGLPFFYDQFLNVRRATQAGFGLGLDHTTMTQQELKETIEILLKEPRFAQIARQMSERYRDQPMSPLDTAIWWTEYVLRHKGAYHMRVAGQDLGFFAYHSLDVIGVLLGGALLLVAIIVGVLGKLTDFGNAKKKLKSK", "length": 516 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VGT1-1", "protein_name": "UDP-glycosyltransferase family 35 member E2", "gene_name": "Ugt35E2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPMSMLVLRLIVLVVALLPVLLEGARILGVFPIPSHSHYYHALPYLKKLASLGHEITSVSPFPLKEPVANIHDIPVPELFDNIEEIVGNLTNRKGTWNEFEYINQYTLGLVEKVLENDGVRREILQPESLQFDLIIVDLWRLDALYGLAAYFDAPIIGIASYGTDWKIDELVGNVSPLAYLQSPSFNWFDLDTYGGRLGHFVDQSMAWINWHWRHEERHEAVYRKYFPKIADKRSLSEITRNFALILVNQHFTMAPPRPYVPNIIEVGGMHVDQQPKALPQDLEDFIQGAGEHGVIYFSLGTNVRSRNLSKDRRKILIDTFASLPQRILWKFDADELSDVPSNVLISPWFPQQDILAHPNVKLFITHGGLQSTVECIHRGVPMLGLPFFYDQFRNMEHIKAQGIGLVLNYRDMTSDEFKDTIHQLLTEKSFGVKAKRTADRYRDQPMNPLDTAIWWTHYVLRHKGAPHMRVAGRNLDFITYHSLDVLGTFLLAVWAILSIVVLCAIKLLRAILKSKKGNISPKQKIN", "length": 527 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VGT2-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt35E1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLASGLFYLIILLFPGFLYGARILALFPVPSHSHYYHALPYLKNLASLGHEITSVSPFPSEEPVKNIYDIYVPEVLNSFDELLKQMTTPKNTWEFFDATNEFVYNITKDVFNNDGVRREILRPGKAQFDLIIVDIWKYDAFYSLAAYFEAPIIGLAPCGIDWKIDEMVGNPSPMSYLQSPSSYLYNLDTFGGRVAHVVEVAISWFNWHWRYEQKHEALYKKYFPKIAETKPLSEISQDIALVLVNQHFTLGPPRPYVPNVIEVGGMHIDEQPKALAQDLEDFIQGSGEHGVIYFSLGTNVRTKNMVDDRKRILIEAFGSLPQRVLWKFEDEELQDIPSNVLVRKWLPQQDLLAHPKVKLFITHGGMQSTIESIHYGKPMLGLPFFYDQFTNVDHIKKHGFCLSLNYHDMTSDELKATILQLLTEKRFEVTARIAGARYRDQPMKPLETAVWWTHYVLRHKGAPHMRVAGRKLSFFTHHSLDVLGTVLLVILLVIIAILLIIVFSVCKISKNISTRLVVKKQRKQKVR", "length": 527 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VGT3-1", "protein_name": "UDP-glycosyltransferase family 302 member C1", "gene_name": "Ugt302C1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKPTAGQTGFLALLLFCLLSCVSAYNYLVVLHTAARSHYHVGSALAKGLAAAGHQVTIISPFELKKPIKNIKDVPAKSILTSMQGRIANLLQSSKEPIIKQIINFHEMGIEITELLLKEPSVIELMKSNQTFDAVISEVFLNEAHFGFAEHFKAPLIGLGTFGAISWNTDLVGSPSPPSYVPSALLKFSDRMSLVERVGNQAFLTYEYIFLNYFYLPRQEVLYRKYFPNNKQDFYDMRKNTALVLLNQHVSLSFPRPYSPNMIEVGGMHINRKRQPLPKDILEFIEGAEHGVIYFSMGSNLKSKTLPLEKRQALIDTFAQLKQRVLWKFEDTDLPGKPANVFISDWFPQDDILAHDNVLAFITHGGLLSTTESIYHRKPFVGIPIFGDQFLNMARAEQNGYGVTVHYEELSSAKLLAAIQKIINNPEATQRVRDMSDRYRDQQQTPLERAVYWVEHVSRHKGAKYLRSASQDLNFIQYHNLDAMLILYGGIIFVLYCIFLLIRLVWRLLQELFIKKDTSKPKQKAKRN", "length": 528 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VGT4-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt302E1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRWLLNSWLLLILALFGQSWGYSYLMISHTASKSHYAVCFALAKGLAAAGHEVTLVSPFPQRKPIKNIIDVETPNIITVMGVYKARILENAKKPVLLRYPRISLMGLDITESLLKEPKVQELLKQNRTFDGVICETFMNDAHYGFAEHFGAPLITLSSLGATGWTSDLVGTPSPPSYVPHSLLRFGDRMNFWERAQNLGFQIYEFAYENLINLPRHEALYRKYFPNNKQDFYRMRKDTSLVLLNNHVSISNPRPYSPNMIEVGGMHVNRKAPKPLPQNIRKFIEEAEHGVIYFSLGSNLNSKDLPENKRKAIVETLRGLKYRVIWKYEEETFVDKPDNVLISNWLPQDDILAHEKVIAFITHGGLLSTMESIYHGKPVVGIPFFGDQFMNMARAEQMGYGITVKYAQLTASLFRSAIERITSDPSFTERVKVISSQYRDQKETPLERAVYWVEHVTRHKGAKYLRSACQDLNFIQYHNLDVLATFFSVIGLTVIFVFLLVRFLVTIVNGFLYKPSSKLKIN", "length": 521 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VGT5-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt302K1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRTFTLILGLLCSLGYSSGYNYLMVLNSAGRSHFNVGHALAKGLVKAGHTITVVSVFPQKKPIPGYTDVSVPNVIEVMGGDIGALWASIQKTYTQNLIDHYQMGFRITRGLFEDSNFQDFLKSNQSFDAIICETFYNDAHYGLAEHFNAPLIGLATGGGLTFITDMVGSPAPASFVPHIMLPFNDHMSLYERLLNVAFLGYERVLLDYYFLPTQEKLYKEFFPGNKRCFYKMRRNASLVLINQHVSLSFPRPHSPNMIEVGGMHIDGKWNPLPEKIERFINESEHGAIYFSMGSNLKTKDLPPSKVQEILKALGGLKQRVLWKFELDNLPNKPENVYISDWFPQTDILAHPKIMAFVTHGGMLSTTESIYHAKPVIGLPIFSDQFFNMAHAEQNGYGIMLDFKTLNAVEFRKAIERITSEPSYTKVVQGISFRYRDQQQTPIENAIYWVEHVTRHQGAAYLKSAAQRLNWWQYHNVDVLLIIFVVMVLLLIVLPITIYKLLKKLLLKGERTQSTKVKRN", "length": 519 }, "evidence": [ { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VGT8-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt35C1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRLLTVIAIVFCALSAKPLESESAKILATLPFPGRSQYIFVESYLKALAAKGHQVTVINAFKNKETPNMRFIEALKAHEFADEMMSLLNVPLLWQQLNAMDYILNKFIDVTMEDEGVQRLLNSGETFDLVLAEMLHMEPMYAFAQHFNATLVGFSSFGTDRTIDEAAGNISPISYNPLVTSPRTDRMTFLERLENHYEVIVEDIHRHFVHLPHMRNVYKKYFPNAKKTLEEVMDSFSLILLGQHFSLSYPRPYLPNMIEVGGMHISHKPKPLPEDIKQFIEGSPHGVIYFSMGSNVKSKDLPQETRDTLLKTFAKLKQRVLWKFEDDDMPGKPANVLIKKWYPQPDILAHPNVKLFISHGGLLSSTESVYFGKPILGLPCFYDQHMNVQRAQRVGFGLGLDLNNLKQEDLEKAIQTLLTDPSYAKASLAISERYRDQPQSAVDRAVWWTEYVIRHNGAPHLRATSRDLNFIQLNSLDTLAVILAVPLLLALLIVTLSCKLLGGKKQKCLHADKLKKH", "length": 517 }, "evidence": [ { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VIM9-1", "protein_name": "UDP-glycosyltransferase family 37 member A1", "gene_name": "Ugt37A1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVGRTKSYFVIVLALTLLIYGAQGANILGLFPSLSPSHLIISMSVAKILAEQGHNVTVVTVLEPTITHKNINLVTVPMTKEEIKQRSETIGAKQKNTSSNRFISILNMSGQMDSMLRKMADVLKDQRVKELYLNKDNHFDLVISGYFMNDYQLGFARKVNAPVVVLAPSPPSQMLNSLIGNPHDKVEKEKGMTFGQRLDSYISSLLYGIFLRQIDQRNRQYYNEIFGDDPTMPEYTDILRNTSLVFFCSHAASEGPIRPSVPAAIEIGGIQIKDKPDPLPKNLEKFLGNATHGAILLSLGSNVQGSHIKADTVKKIFSVLSNLKQRVIWKWDDLDKTPGKSDNILYSRWLPQDDILAHPSVKLFINHAGKGGISEAQYHGKPMLSLPVFGDQPGNAHAMVKSGFGLTLSLLTLEEEPFRAAVLEILSNPKYSQRVVKFSSLYRDRPASARESLIFWTEYVIRHHGAAHLQSPLVHMDFIAANNLDIYALIGAISIGLLLMLKKVVQITCRRLRTKLNKVKKQ", "length": 522 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VJ45-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt36E1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MCGCWKVFCLLALLSLVAFSDSLRILGLFPHPAISHFKFFHPIMRGLAEAGHSVDVISPFEDKDPPNGYKDHLLPPSTLTDTISLEDFERPYSFLFHYVEFFILHKMGREDCNTTLHSRALTEILKNPPGYYDVILLEQFNTDCAMSVAHVFQAPVIGMSSCALMPWHYERFGAPLIPSYISALFQGQSQEMSFAGRLGNWITVHSLNLLYKMFTVPAGNALIRQRFGPGLPSTEDLVRNTSLMLVNQHFSLSGPKPLPPNVIEVGGVHISPPKPLPSDLQKILDNAPKGVILISWGSQLKACSLSAARRDGIVKAIGRLEQEVIWKYENDTLPNKPPNLHIRKWLPQRDILAHPNLKVFMSHGGLMGTTEAVSSAVPIVGVPIYGDQSLNIAALVQRGMALQLELKKLDENTVYEALTKALDPSFKARAKEVASSYNNRIQGPLETAIWWVEHVAETKGAPLTQPSAVHLSRFVYYSLDVYSVVALSLLLPVITLLGLIRMFKRREPKGDRKLKRK", "length": 517 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VJ46-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt36D1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MWSPRVALLFLALALSQPDELVEAAGPLKVLGLFPHPGVSHFHFFHPIMKGLAEAGHDVSVVSHFPDKHPVAHYKDFPLTGMDKLTNSVDLKFFEKRTFYSHFQEFFLLYDWGKQTCNLTLRSEALQQILRRPGRFDVIIMEQFNTDCMMGVAHQLQAPVIALSSCVMMPWHYERMGAPLIPSHIPALFMAQSQHMNFGGRLANWFSTHALNWMYKLLSVPAADAMVQYKFGHDVPSVGELVKNTSMFFVNQHYSLSGPKVTPPNVIELGGIHIQKSKPLPADLQRILDNAEEGVILISWGSMIRANSLSAAKRDGIIRAVARLKQKVIWKWENETLPNQPPNMHIMKWLPQRDILCHPNVKVFMSHGGLMGTSEAAYCGVPVVATPMYGDQFVNTAALVERGMGTILNFEDIGENTVMRALKKALDKKFHDAAKVVSHSFHHRPQQALHTAIWWVEHVAHTGGAPLLKPSAVEMSRFVYYSLDVYAVLALVLGSIIASWVWLLRLCCGSSAAQKTKKD", "length": 519 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VJ47-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt36F1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKLLPLALLAFLLRPKPNDAAHILGLFQHPGKSHFDFFRPMFLALAERGHNISMYSYFPLEKPVANYTDYVFQGMPLLTDIVDLSNFESEWKPLGLPFKVPTYFMLHDWGLRSCKVALNSPLITQLLKSPIRYDVILLEHFSNDCMAAVAHLLNAPVIALSSCAIMPWHYKRMGSPFINPIMPMNFLPYTDEMSLIDRLNNFFHFHTVNTLYNMITQPATDALIAERFGPGLPPINEIVKNTSLMLINQHYALTGPRPYAPNVIEVGGLQVGPIKPLPQHLLDLLDRSPNGVIYISWGSMVNSNTLPSGKRSALFQSISQLKEYNFVMRWKSLESLEDKQPSNLYTFDWLPQRDLLCHPKIRAFISHGGLLGTTEAIHCGVPMLVTPFYGDQFLNSGAVKQRGFGVIVDFRDFDSNHITRGLRIILDKKFAERVRRSSEAFRQRPIPPIKLATWWIEHVIKYGGAPHIQSEARHINWIVYNSIDVLLFWLGILFLLIVALRKLIKIFKTAFCRGKISRDTKTKTQ", "length": 525 }, "evidence": [ { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VJ81-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt301D1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEMQLQWKCWMLIFLIGLLEFGAGSRILFMGPFPAPSHWLWLEHFQNDLLRQGHHVTSVNNHPTKHPHENLTEIIISPSFDIPKHFPKENIFSMQFVSDFNNLELWWTIGLMTTEHAFKDPKVKKLIESKDDHYDLVIIEQFFHEAFLMFGKRFNCPVVTIGTMGYADNIDHAMGILTPWSLIPHLLLSHTDRMTFGQRAYNAYLSLYDAVMRRWVYLPKMQKLAEKYFQGSIEGPLPNVLDLERNISLVLINAHRSIDLPRPSMPGLIDVGGAHIQKPKQLPTDLQNFLDNATYGVIYFSMGSYVKSTDLPQEKTALILKAFGQLKQQVIWKFENDSIGDLPSNVMIKKWMPQNDILAHPNVKLFITHGGIFGTQEGIYWGVPMLCVPLYGDQHRNTIKSVREGYARSLVFSKLTTDDLVRNIETLINDPQYKRSALEVSQRFRDNPIHPLDEATFWIEYIIRHRGARHLKSHGAFIPLHQYLLLDVLGCLLLGAFLAIWLPWRMIRRVHKWWLKGESSNKLNEGKKRL", "length": 530 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VJH8-1", "protein_name": "UDP-glycosyltransferase family 37 member D1, isoform C", "gene_name": "Ugt37D1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTQNRSTWIGCSLGGLLVALLALQTMPQGTEGANILGVFTSHSPSHFIVHMSIMKTLAEKGHNVTVVSSVPPKVTHKSINHIVVPMSAEDEKVLNDGMAGMVKEKPSIWNTMKSIFSSLALLIDKQVDVLEDPRFQELYLNKGNKFDVVFVGFFFNTYQVALGARFNCPVIISWSGPPMMMVNEVLGNPELSSVPQMHISAPPGQPMNFQQRMQNFASTLGFNALNIFLNHKYNKFYDRLWSKDKSMPTFAQAKRNVSLAFCNGHGISEGPIRPNVPGVIEIGGIQVKSKPDPLPEDIQEFLEKGKHGAILFSLGSNLKGEHIQPEVVKTIFKGLSSLKQQVIWKWEDPKNTPGKSANILYKKWLPQDDILAHPKLKLFITHAGKGGVAEAQYHGVPMLALPVFADQPGNADKLVASGYGLQLPLATLDVDEFKAAIKEVIENPKYAKTLKSFSQLYRDRPLSPQESVVYWTEYVIRHHGAAHMQSPLVHMNFIASNNLDIYIIAALVLYIVFIINKIVWKFVWRKLFGKSNKVSKGKKVKKQ", "length": 543 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VJH9-1", "protein_name": "UDP-glycosyltransferase family 37 member E1", "gene_name": "Ugt37E1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MIEYTKIGFLIAFLLSTMTQSSGGANILGVFGTHSPSHVIVHMAVMKALADRGHNITVVTQMKPKLATHENITVIIAPPTEERQRYIKEYMAEVSNEKPSFWETMVKAIVQSSNQLEGQYEFMTHPNVKEIYENPKIKFDLVFLGLMANTYQLGIAAKLKCPVIISWVGIPLPFMDTIVGNVNDPSYVPTVNVALNAGQKTMDFGLRFVNFFKYAIMCVFETVLDYKMNQFYERAFANELEFPNYHEMKRRVSLLFYNYHSASEGPIRPTVPQSIEIGGIQVKEQADPLPKELAKFLDKADEGAIFFSLGTNVNTNTFRPDTVDILYKVLSKLPQRVIWKWEDLKNKPGNASNIFFGNWLPQDDILAHPNTKLFITHAGKGGVAEAQYHGVPMVALPIFGDQQGNAEIMTKSGFGRWLDILTMTEHELEQTIREVLGNPAYRETIGKFSTLYRDRPLTARQSVIYWTEYVLRHQGALHLQSPLIHTKFVARNNLDVYGVVLLVSLLLIVTIKFLFRKILNVAIGYGSQRKAVANKLKNN", "length": 539 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VJI0-1", "protein_name": "UDP-glycosyltransferase family 37 member C2, isoform B", "gene_name": "Ugt37C2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MIGVHFVFLLLLGVVASTQGANILGLFSSHSPSHLIIHMSVAKALVKAGHNVTVVSMLKPKVTHKDIHLIVVPMKEEQERIMEDQMTEMAGQKNSLVSTMYRLLTSMDVMINAQAELLSDPRFQRIYETKFDLMILGYFINDFQLGVAHKLKVPVIINWMSAPVPAIDKYTGNPSELSYVPLMGTVATQPMGFLKRTENALKSLLFEFIFVVFDYKLTRIYNDVFPEQDMPTLKELRKNISMAFVGSHLISEGPIRPLVPALIEIGGIQVKDKPDPLPKDIDQFISNAKQGAVFLSLGSNVKSSTVRPEIVQIIFKVLSELKENVIWKWEDLENTPGNSSNILYKNWLPQDDILAHPNTKLFITHAGKGGITEAQYHGVPMVALPIFGDQPGNAALMEKSGYGLALDLLSITEDSLRDALKEVLENQKYKQAIGQFSTLYRDRPMTAKQSVVFWTEYILRHQGAPNLQSPSVHMNFIQLNNLDIYALIVTILVLFVLLTRLVAKIVWNKFGGKAKISQTKKKQ", "length": 523 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VQT0-1", "protein_name": "UDP-glycosyltransferase family 36 member A1, isoform A", "gene_name": "Ugt36A1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTTCLRSGVLIIVLLGILGIPEPISAGNILAVYPHFGFSHFKVVMPILNELAHRGHDITVISYVKNPQAGAYPNYEELLISAPGEDQSSTTINLVPLTEHTPTRSLGVLIREYVDLHEEGQKTCEHLFASGHIERAIERHRNKPYDLLLTEYFNSDCQLALAKLLNLPIIGLSTCALMPYYYDRIDLPDTPAFIQSEFVGFAGQLNWHERLLNFVQAKLLKFLYKYHSNRADNELVRKYLGVEVDVEEVARTQTAFIFGNQHYSLMGSRPQSLQFVEIGGVHITKKAEQELPQNIANFLNQSAEGVIFISWGSMVRASSIDEDKLSAILEVLKSQPLKIIWKWEADETPDTDASKFLFVKWAPQLALLCHPKVKLFWSHGGLLGTTESVHCGKPLLVTPIYGDQFLNAFSVQNRGMGLKLDYQDITVPNLKKALAELSKNSYAQRSLEVSKVFNERQQTPLESAIWSVEHVISNGLIAARLLQSPGIELNGFVYHSLDSVALILLPLILLILVLCYLCKRNPSKLAHKKVGKKPKRS", "length": 537 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VVW2-1", "protein_name": "UDP-glycosyltransferase family 316 member A1, isoform B", "gene_name": "Ugt316A1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MQILQVFLGTLLCGIVLGANVLTVFPSVWKSHYLFGRRLLQELVESSGNHSVTLISPHAAQEGVDAEIPKIRELRIEGLRENWLDMGMSFEAEEMRAQSVMERFTRLIYAGTTNVDILLSDPQVRKLLTSGEKFDLLIVDLFLSDALLGLAFYYGIPTVAVSPTGANSWLNNMFGNPQSSSLDPSNFLPFTERMNTRQRILNSLMSTFERLTYNFFHLISQQSVYTNHFELLVKELPLYRDLTKNLSLALINSHPGLHYPRAYLPNMVEVGGLHLSHLNDDNLPKHLLSFMESAPSGVIYFSLGADVETAQLPQEKLAIILDVFGHLKEFHFLLKWEKEEFTAEQVLPENVMIADWWPQQAILHHPQVKMFISSCGQLSVWESISGQKPVLAIPILAEQEVMAKRLQRHGVSVTVGYDSLAYDSLLHGIRQLTLNTSYVEKLGQLKERLISRDSTPVGKAVRKIQLILESGGADFLKSHANTLNFWRAEGVDVLLIIAVGFFGILTIPFLAICFILRKSYHSQAAQDQPPYRTNLKVVGRVHSYGDQGSSRSPKGTESLRRTRSAQSLSARSSSSSMSSNSPTSPSTASTTPLDLTPPPPIQLLGQVPPLQLYVNQQRIYSSDRKTSQEEAERRFS", "length": 636 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W2J3-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt49C1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MQFPLLFGLLLTGTLYSQLELAEGSKILAVYAFPGKSHFMMHTALIRELVESGHQVTMVTAFSLEKEQLGSNYTEILIEPVYDFWHDVKLNFGAQHLFELTRMTNYDFLKMLEIIGLKTTEHALRQPKVRSLIHAEQKEGVFDLLLAEQFYQEAFLALAHLYKIPVVTTSTLGYENHMSQMMGLITPWSFVPHGFMPFTDRMSFLERVKNSYASFYEDMDRLLNYFPKMDAVAREFFGPVLTEVPKVKHMERQISVMLLNSHAPLTTARPTVDAMVPVGGMHIYPPKPLPADMQALLDGATEGAIFFSLGSNVQSKDMPVEMLRLFLQVFGSLKQRVLWKFEDESISQLPDNVMVRKWLPQADILAHRHVKVFITHGGLFGTQEGVHYAVPMLGIPFYCDQHLNMNKAVLGGYAISLHFQSITEEILRHSLDQLIHNVTYKENVQRVSDIFRDRPLEPRKSAVYWIEYVIRHRGASHMRSAGLDLNWFQFYLLDVIAFVAIIALAGVMALSLAIRLLMGSNKKHRKAKQN", "length": 530 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W2J4-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt49B1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSLKSALHIFLLSLVALQQLELGTGSRILAAFFFPGKSHFMMTNAIIRELVKQGHEVTFITPFSLAKEKLGSNYKEIVIPQYDFWPEIKEMTNKNTVLEMTDLPTFAFLRMVNVMGIHTTDFALEQPEIQAVINEKNKIGKYDLLLAEQFFNEGALILGHLYQIPTITISTFGNANHLSQLFGVVSPWSYVPHAYMPYTDRMTLWERIGNVAMSAAEDLVREFSYYPGQDAVLKKHFSKLLDRVPTIKELERNISAILLNSYMPLASSRPMAYNMIPVGGLHIQPPKALPEHLQKFLDGATHGAIYFSLGSQVRSADLPPEKLKVFLEVFGSLKQRVLWKFEDESLPNLPANVKVQSWLPQGDILAHPNVKVFIAHGGLFGTQEAVYNGVPILGMPVYCDQHQNINQGKSAEYALGLDYRKVTVEELRGLLMELIENPKYRNNIKKASRIFRDRPLGAMDTAIYWINYVIEHRGAPHLVAAGVHLPWYQFYLLDIVGLGLAVILLPIVVLILICRRSSKPKSTPTKKKTKKN", "length": 532 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "UDP-glycosyltransferase activity", "id": "GO:0008194", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008194", "evidence": [ { "database": "UniProtKB", "id": "Q9VMG1", "url": "https://www.uniprot.org/uniprotkb/Q9VMG1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VMG1", "url": "https://www.uniprot.org/uniprotkb/Q9VMG1" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VMG1", "url": "https://www.uniprot.org/uniprotkb/Q9VMG1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 246, "end_pos": 248, "annotation": "n_glycosylation_sequon" }, { "start_pos": 365, "end_pos": 367, "annotation": "n_glycosylation_sequon" }, { "start_pos": 52, "end_pos": 54, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 246, "end_pos": 248 }, { "start_pos": 365, "end_pos": 367 }, { 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"database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285661" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VMH8", "url": "https://www.uniprot.org/uniprotkb/Q9VMH8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Pfdn1", "url": "https://www.uniprot.org/uniprotkb/Q9VMH8", "locus": { "chromosome": "2L", "start_pos": 6069838, "end_pos": 6069079, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0031776", "url": "https://www.ensemblgenomes.org/id/FBgn0031776" } ] } } ], "crossref": [ { "id": "FB:FBgn0031776", "url": "https://alliancegenome.org/gene/FB:FBgn0031776", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0031776", "url": 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"categories": [ "Protein" ] }, { "id": "Q9VMH8", "url": "https://www.uniprot.org/uniprotkb/Q9VMH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VMH8-1", "url": "https://www.uniprot.org/uniprotkb/Q9VMH8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQMDIELKKAFTEMQINKLETTKKIHMIDMKCDMVKTGKQKYQLTEKGTSSLADDTRVYQSVGRMFLLTDVQNMREDLKARQEKCDKAIELLEKKKEFLQKSLKSQEDGLRELVQQRKEADQTAK", "length": 126, "header": "tr|Q9VMH8-1|Q9VMH8_DROME Isoform 1 of Prefoldin 1, isoform B OS=Drosophila melanogaster OX=7227 GN=Pfdn1 PE=1 SV=2 CANONICAL=Q9VMH8-1" }, "isoforms": [ { "isoform_ac": "Q9VMH8-1", "url": "https://www.uniprot.org/uniprotkb/Q9VMH8/entry#Q9VMH8-1", "sequence": { "sequence": "MAQMDIELKKAFTEMQINKLETTKKIHMIDMKCDMVKTGKQKYQLTEKGTSSLADDTRVYQSVGRMFLLTDVQNMREDLKARQEKCDKAIELLEKKKEFLQKSLKSQEDGLRELVQQRKEADQTAK", "length": 126, "header": "tr|Q9VMH8-1|Q9VMH8_DROME Isoform 1 of Prefoldin 1, isoform B OS=Drosophila melanogaster OX=7227 GN=Pfdn1 PE=1 SV=2 CANONICAL=Q9VMH8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VMH8", "url": "https://www.uniprot.org/uniprotkb/Q9VMH8" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VMH8", "url": "https://www.uniprot.org/uniprotkb/Q9VMH8" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMH8", "url": "https://www.uniprot.org/uniprotkb/Q9VMH8" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMH8", "url": "https://www.uniprot.org/uniprotkb/Q9VMH8" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VMH8", "url": "https://www.uniprot.org/uniprotkb/Q9VMH8" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. 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F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMH8", "url": "https://www.uniprot.org/uniprotkb/Q9VMH8" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMH8", "url": "https://www.uniprot.org/uniprotkb/Q9VMH8" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"3.1.3.95", "type": "synonym", "evidence": [ { "id": "Q9VMI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMI9/entry#names_and_taxonomy" } ] }, { "name": "CG9115-PB", "type": "synonym", "evidence": [ { "id": "NP_001285651", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285651" } ] }, { "name": "mtm-PB", "type": "synonym", "evidence": [ { "id": "NP_001285651", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285651" } ] }, { "name": "myotubularin, isoform B", "type": "synonym", "evidence": [ { "id": "NP_001285651", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285651" } ] }, { "name": "myotubularin", "type": "synonym", "evidence": [ { "id": "NP_001285651", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285651" } ] } ], "function": [], "disease": [ { "disease_id": "DOID:0110191", "recommended_name": { "id": "DOID:0110191", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110191", "name": "Charcot-Marie-Tooth disease type 4B1", "description": "A Charcot-Marie-Tooth disease type 4 that has_material_basis_in mutation in the gene encoding the myotubularin-related protein-2 (MTMR2)." }, "synonyms": [ { "id": "DOID:0110191", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110191", "name": "CMT4B1", "description": "" }, { "id": "DOID:0110191", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110191", "name": "Charcot-Marie-Tooth neuropathy type 4B1", "description": "" }, { "id": "DOID:0110191", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110191", "name": "autosomal recessive Charcot-Marie-Tooth disease with focally folded myelin sheaths type 4B1", "description": "" }, { "id": "MONDO:0011066", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011066", "name": "Charcot-Marie-Tooth disease type 4B1", "description": "Charcot-Marie-Tooth disease type 4B1 (CMT4B1) is a subtype of Charcot-Marie-Tooth disease type 4 characterized by an early childhood-onset of severe, demyelinating sensorimotor neuropathy, various degrees of complex myelin outfoldings seen on peripheral nerve biopsy, very slow, and often undetectable, nerve conduction velocities, and the typical CMT phenotype (i.e. distal muscle weakness and atrophy, sensory loss, and frequent pes cavus). Other reported features include facial weakness, vocal cord paresis, respiratory difficulties, and skeletal deformities (e.g. chest deformities, claw hands, pes equinovarus)." }, { "id": "MONDO:0011066", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011066", "name": "CMT4B1", "description": "" }, { "id": "MONDO:0011066", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011066", "name": "Charcot-Marie-Tooth disease type 4 caused by mutation in MTMR2", "description": "" }, { "id": "MONDO:0011066", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011066", "name": "Charcot-Marie-Tooth disease type 4B1", "description": "" }, { "id": "MONDO:0011066", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011066", "name": "MTMR2 Charcot-Marie-Tooth disease type 4", "description": "" }, { "id": "MONDO:0011066", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011066", "name": "CMT 4B", "description": "" }, { "id": "MONDO:0011066", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011066", "name": "CMT 4B1", "description": "" }, { "id": "MONDO:0011066", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011066", "name": "Charcot Marie Tooth disease type 4B1", "description": "" }, { "id": "MONDO:0011066", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011066", "name": "Charcot-Marie-Tooth disease, type 4B1", "description": "" }, { "id": "MIM:601382", "resource": "MIM", "url": "https://www.omim.org/entry/601382", "name": "Charcot-Marie-Tooth disease, demyelinating, type 4B1", "description": "Charcot-Marie-Tooth disease, demyelinating, type 4B1" } ], "unlinked_id_list": [], "evidence": [ { "id": "0110191", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110191" } ] }, { "disease_id": "DOID:0111225", "recommended_name": { "id": "DOID:0111225", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111225", "name": "centronuclear myopathy X-linked", "description": "A centronuclear myopathy that has_material_basis_in X-linked inheritance of mutations in MTM1 on Xq28." }, "synonyms": [ { "id": "DOID:0111225", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111225", "name": "CNMX", "description": "" }, { "id": "DOID:0111225", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111225", "name": "MTM1", "description": "" }, { "id": "DOID:0111225", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111225", "name": "X-linked myotubular myopathy", "description": "" }, { "id": "DOID:0111225", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111225", "name": "XLCNM", "description": "" }, { "id": "DOID:0111225", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111225", "name": "XLMTM", "description": "" }, { "id": "DOID:0111225", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111225", "name": "myotubular myopathy 1", "description": "" }, { "id": "MONDO:0010683", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010683", "name": "X-linked myotubular myopathy", "description": "A rare X-linked congenital myopathy characterized by numerous centrally placed nuclei on muscle biopsy and that presents at birth with marked weakness, hypotonia and respiratory failure." }, { "id": "MONDO:0010683", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010683", "name": "MTM", "description": "" }, { "id": "MONDO:0010683", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010683", "name": "X-linked centronuclear myopathy", "description": "" }, { "id": "MONDO:0010683", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010683", "name": "X-linked myotubular myopathy", "description": "" }, { "id": "MONDO:0010683", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010683", "name": "XLCNM", "description": "" }, { "id": "MONDO:0010683", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010683", "name": "XLMTM", "description": "" }, { "id": "MONDO:0010683", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010683", "name": "centronuclear myopathy, X-linked", "description": "" }, { "id": "MONDO:0010683", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010683", "name": "myotubular myopathy, X-linked, X-linked recessive", "description": "" }, { "id": "MONDO:0010683", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010683", "name": "CNMX", "description": "" }, { "id": "MONDO:0010683", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010683", "name": "myopathy, centronuclear, X-linked", "description": "" }, { "id": "MIM:310400", "resource": "MIM", "url": "https://www.omim.org/entry/310400", "name": "Myopathy, centronuclear, X-linked", "description": "Myopathy, centronuclear, X-linked" } ], "unlinked_id_list": [], "evidence": [ { "id": "0111225", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111225" } ] }, { "disease_id": "DOID:10595", "recommended_name": { "id": "DOID:10595", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10595", "name": "Charcot-Marie-Tooth disease", "description": "A neuromuscular disease that is characterized by a slowly progressive degeneration of the muscles of the foot, lower leg, hand and forearm." }, "synonyms": [ { "id": "DOID:10595", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10595", "name": "CMT - Charcot-Marie-Tooth disease", "description": "" }, { "id": "MONDO:0007309", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007309", "name": "Charcot-Marie-Tooth disease type 1A", "description": "Charcot-Marie-Tooth disease type 1A (CMT1A) is a type ofinherited neurological disorder that affects the peripheral nerves. Affected individuals experience weakness and wasting (atrophy) of the muscles of the lower legs beginning in adolescence; later they experience hand weakness and sensory loss. CMT1A is caused byhaving an extra copy (a duplication) of the PMP22 gene. It is inherited in an autosomal dominant manner. Treatment for this condition may include physical therapy ; occupational therapy ; braces and other orthopedic devices; orthopedic surgery;and pain medications." }, { "id": "MONDO:0007309", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007309", "name": "CMT1A", "description": "" }, { "id": "MONDO:0007309", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007309", "name": "Charcot-Marie-Tooth disease type 1A", "description": "" }, { "id": "MONDO:0007309", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007309", "name": "Charcot-Marie-Tooth disease, type 1A", "description": "" }, { "id": "MONDO:0007309", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007309", "name": "Charcot-Marie-Tooth syndrome type 1A", "description": "" }, { "id": "MONDO:0007309", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007309", "name": "HMSN1A", "description": "" }, { "id": "MONDO:0007309", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007309", "name": "hereditary motor and sensory neuropathy 1A", "description": "" }, { "id": "MONDO:0007309", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007309", "name": "microduplication 17p12", "description": "" }, { "id": "MONDO:0007309", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007309", "name": "CMT 1A", "description": "" }, { "id": "MONDO:0007309", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007309", "name": "Charcot Marie Tooth disease type 1A", "description": "" }, { "id": "MONDO:0007309", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007309", "name": "Charcot-Marie-Tooth disease, demyelinating, type 1A", "description": "" }, { "id": "MONDO:0007309", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007309", "name": "HMSN 1A", "description": "" }, { "id": "MIM:118220", "resource": "MIM", "url": "https://www.omim.org/entry/118220", "name": "Charcot-Marie-Tooth disease, demyelinating, type 1A", "description": "Charcot-Marie-Tooth disease, demyelinating, type 1A" } ], "unlinked_id_list": [ "DOID:0050542", "DOID:0050538", "DOID:0050541" ], "evidence": [ { "id": "10595", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10595" } ] }, { "disease_id": "DOID:14717", "recommended_name": { "id": "DOID:14717", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14717", "name": "centronuclear myopathy", "description": "A congenital structural myopathy characterized by abnormally located nuclei in skeletal muscle cells. The nuclei are located in the center of the cell, instead of their normal location at the periphery." }, "synonyms": [ { "id": "DOID:14717", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14717", "name": "myotubular myopathy", "description": "" } ], "unlinked_id_list": [ "DOID:0111217" ], "evidence": [ { "id": "14717", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14717" } ] }, { "disease_id": "DOID:422", "recommended_name": { "id": "DOID:422", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:422", "name": "congenital structural myopathy", "description": "A myopathy that is characterized by hypotonia, muscle weakness, and delayed development of motor skills." }, "synonyms": [], "unlinked_id_list": [ "DOID:0111217" ], "evidence": [ { "id": "422", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:422" } ] }, { "disease_id": "DOID:423", "recommended_name": { "id": "DOID:423", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:423", "name": "myopathy", "description": "A muscular disease in which the muscle fibers do not function resulting in muscular weakness." }, "synonyms": [], "unlinked_id_list": [ "DOID:0111217", "DOID:0111267" ], "evidence": [ { "id": "423", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:423" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VMI9", "url": "https://www.uniprot.org/uniprotkb/Q9VMI9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "mtm", "url": "https://www.uniprot.org/uniprotkb/Q9VMI9", "locus": { "chromosome": "2L", "start_pos": 6034731, "end_pos": 6037015, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0025742", "url": "https://www.ensemblgenomes.org/id/FBgn0025742" } ] } } ], "crossref": [ { "id": "FB:FBgn0025742", "url": "https://alliancegenome.org/gene/FB:FBgn0025742", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0025742", "url": "https://bgee.org/?page=gene&gene_id=FBgn0025742", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13357", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13357", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14535", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14535", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0025742", "url": "https://flybase.org/reports/FBgn0025742", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "33845", "url": "https://www.ncbi.nlm.nih.gov/gene/33845", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VMI9", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VMI9*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR003595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016130", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016130", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030564", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030564", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG9115", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG9115", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WRATKIN", "url": "https://omabrowser.org/oma/group/WRATKIN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VMI9", "url": "https://www.orthodb.org/?gene=Q9VMI9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10807", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10807", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10807:SF128", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10807:SF128", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02893", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02893", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06602", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06602", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-1483248", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1483248", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-1660499", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1660499", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-1660516", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1660516", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-1660517", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1660517", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-9035034", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9035034", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001285651", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285651", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VMI9", "url": "https://www.uniprot.org/uniprotkb/Q9VMI9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VMI9-1", "url": "https://www.uniprot.org/uniprotkb/Q9VMI9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDPSASLADKLASKTASSNSLDSSSKSSSLGSKHGGGENGILRDTPFGYLEGEEDQDQKNDVTYVCPYRGPVFGALTITNYRLYFRSLPLRDQEPPVVVDVPLGVIARVEKIGGATSRGENSYGIEIFCKDMRNLRFAHKQQNHSRRTVFEKLQANAFPLSYSGRLFAFAHAAANSVNGNGGWDGWAVYEPLAELRRLGVPNDMWRATKLNESYAICDSYPAVWAVPKAASDDFLRRVAQFRSRCRLPVLSWMNPRTQATITRCSQPLVGVSGKRNSDDEAYLSFIMEANAQSDKLTIMDARPSANAIANKAKGGGYESEDAYKNVEINFLDIHNIHVMRESLRKVKEACFPTTDDSKWQTAIDNTLWLKHIRCILAGAVRIVDKVETMSTSVVVHCSDGWDRTAQLTALSMLLLDPHYRTVRGFEVLIEKEWLSFGHKFQQRIGHGDNKHSDADRSPVFLQFIDSVWQVSQQFNNAFEFNEHFLITIVDHLYSCRFGTFLCNTEAERVAEDLKHKTTSLWTHINSSLDQYLNPLFPSFTHGAELVLRPIASVRSVRLWKGLYCRWNPGLCAPQHGCQRTRELLSKQDQLFKLVNELRLKSNNRSNSMQTTTRLASPMH", "length": 619, "header": "tr|Q9VMI9-1|Q9VMI9_DROME Isoform 1 of phosphatidylinositol-3,5-bisphosphate 3-phosphatase OS=Drosophila melanogaster OX=7227 GN=mtm PE=1 SV=1 CANONICAL=Q9VMI9-1" }, "isoforms": [ { "isoform_ac": "Q9VMI9-1", "url": "https://www.uniprot.org/uniprotkb/Q9VMI9/entry#Q9VMI9-1", "sequence": { "sequence": "MDPSASLADKLASKTASSNSLDSSSKSSSLGSKHGGGENGILRDTPFGYLEGEEDQDQKNDVTYVCPYRGPVFGALTITNYRLYFRSLPLRDQEPPVVVDVPLGVIARVEKIGGATSRGENSYGIEIFCKDMRNLRFAHKQQNHSRRTVFEKLQANAFPLSYSGRLFAFAHAAANSVNGNGGWDGWAVYEPLAELRRLGVPNDMWRATKLNESYAICDSYPAVWAVPKAASDDFLRRVAQFRSRCRLPVLSWMNPRTQATITRCSQPLVGVSGKRNSDDEAYLSFIMEANAQSDKLTIMDARPSANAIANKAKGGGYESEDAYKNVEINFLDIHNIHVMRESLRKVKEACFPTTDDSKWQTAIDNTLWLKHIRCILAGAVRIVDKVETMSTSVVVHCSDGWDRTAQLTALSMLLLDPHYRTVRGFEVLIEKEWLSFGHKFQQRIGHGDNKHSDADRSPVFLQFIDSVWQVSQQFNNAFEFNEHFLITIVDHLYSCRFGTFLCNTEAERVAEDLKHKTTSLWTHINSSLDQYLNPLFPSFTHGAELVLRPIASVRSVRLWKGLYCRWNPGLCAPQHGCQRTRELLSKQDQLFKLVNELRLKSNNRSNSMQTTTRLASPMH", "length": 619, "header": "tr|Q9VMI9-1|Q9VMI9_DROME Isoform 1 of phosphatidylinositol-3,5-bisphosphate 3-phosphatase OS=Drosophila melanogaster OX=7227 GN=mtm PE=1 SV=1 CANONICAL=Q9VMI9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VMI9", "url": "https://www.uniprot.org/uniprotkb/Q9VMI9" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VMI9", "url": "https://www.uniprot.org/uniprotkb/Q9VMI9" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMI9", "url": "https://www.uniprot.org/uniprotkb/Q9VMI9" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMI9", "url": "https://www.uniprot.org/uniprotkb/Q9VMI9" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VMI9", "url": "https://www.uniprot.org/uniprotkb/Q9VMI9" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VMI9", "url": "https://www.uniprot.org/uniprotkb/Q9VMI9" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VMI9", "url": "https://www.uniprot.org/uniprotkb/Q9VMI9" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMI9", "url": "https://www.uniprot.org/uniprotkb/Q9VMI9" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMI9", "url": "https://www.uniprot.org/uniprotkb/Q9VMI9" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VMI9", "url": "https://www.uniprot.org/uniprotkb/Q9VMI9" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VMI9", "url": "https://www.uniprot.org/uniprotkb/Q9VMI9" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG9115", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG9115", "resource": "KEGG Pathway" }, { "id": "R-DME-1483248", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1483248", "resource": "Reactome", "description": "Synthesis of PIPs at the ER membrane" }, { "id": "R-DME-1660499", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1660499", "resource": "Reactome", "description": "Synthesis of PIPs at the plasma membrane" }, { "id": "R-DME-1660516", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1660516", "resource": "Reactome", "description": "Synthesis of PIPs at the early endosome membrane" }, { "id": "R-DME-1660517", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1660517", "resource": "Reactome", "description": "Synthesis of PIPs at the late endosome membrane" }, { "id": "R-DME-9035034", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9035034", "resource": "Reactome", "description": "RHOF GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JXT6-1", "protein_name": "Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR6", "gene_name": "Mtmr6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEHIRTTKVEQVKLLDRFSTNNKSLTGTLYLTATHLLFIDAHQKETWILHHHIASVEKLALTTSGCPLVIQCKNFRIVHFIVPRERDCHDIYNSLLQLSKQAKYEDLYAFSYNPKQNDTERLNGWQLIDLAAEYERMGVPNANWQLSDANREYKVCETYPRELYVPRTASRPVIVGSSNFRSKGRLPVLSYCQQGTEAAICRCSQPLSGFSARCLEDEHLLQAISKANPGNRYMYVVDTRPKLRMQSWWDTQKDIGRIIVRISSKIWNDEKIRESDEKKRLNAMANRAAGKGYENEDNYSNIRFQFVGIENIHVMRSSLQKLLEVNGSKGLSVNDFYSGLESSGWLRHIKAVLDAAIFLAKAIVVENASVLVHCSDGWDRTSQVCSLGSLLLDSYYRTMKGFMVLIEKDWISFGHKFSERCGHLDGDPKEVSPVFTQFLECVWHLTEQFPQAFEFNEAFLLQIHEHIHSCQFGNFLGNCQKEREELRLKEKTYSLWPFLLADKKKYLNPLYSSKSQRLTVLEPNTASFNFKFWRNMYHQFDRTLHPRQSVLNIIMNMNEQNKQLEEDVKDLEAKIKQCKSGILTKDLLHAVHPESPSLKTSLCLKEQSLLPVKDTLRAVEGSSPADNRYCDYTEEFSKSEPAVVSLEYGVARMTC", "length": 655 }, "evidence": [ { "id": "SGD:S000003871", "url": "https://alliancegenome.org/gene/SGD:S000003871#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y1D5-1", "protein_name": "phosphatidylinositol-3,5-bisphosphate 3-phosphatase", "gene_name": "Mtmr1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDRPGAAASGCESAAGPGPGPGASWRPARVAGGASGSSRHPSMETLDSPAGSHVEWCKQLIAATISTQMSGSVTSENVSRDYKVFRRPDTRELQEEHNGYPSAAEADQALRDGNKLAQMEEAPLFPGESIKAIVKDVIYICPFAGAVSGTLTVTDFKMFFKNVERDPHFILDVPLGVISRVEKIGAQSHGDNSCGIEIVCKDMRNLRLAYKQEEQRKLGIFENLNKHAFPLSNGQALFAFNYKEKFPVNGWKVYDPVSEYKRQGLPNESWKISKINSNYEFCDTYPAVIVVPTSVKDDDLLKVSAFRAKGRVPVLSWIHPESQATITRCGQPLVGPNDKRCKEDEKYLQTIMDANAQSHKLTIFDARQNSVADTNKAKGGGYECESAYPNAELIFLEIPNIHVMRESLRKLKEVVYPAIDESHWLSNVDGTHWLEYIRVLLAGAVRIADKIESGKTSVVVHCSDGWDRTPQLTSLAMLMLDSYYRTIPGFEALIEKEWISFGHRFALRVGHGDDNHADADRSPIFLQFIDCVWQMTRQFPSAFEFNELFLIAILDHLYSCLFGTFLCNCEQQRVREDVCAKTLSLWSYINSQLDEFSNPFFVSYDHHVLYPVASVSRLELWVNYYVRWNPRMRPQMPIHQNLKELLAVKAELRKRVEDLQREAAARTVPSSSERGPSPTHSAPPVHTSV", "length": 689 }, "evidence": [ { "id": "MGI:1858271", "url": "https://alliancegenome.org/gene/MGI:1858271#orthology", "database": "AGR" }, { "id": "HGNC:7449", "url": "https://alliancegenome.org/gene/HGNC:7449#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050522-518", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-518#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050327-48", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050327-48#orthology", "database": "AGR" }, { "id": "FB:FBgn0025742", "url": "https://alliancegenome.org/gene/FB:FBgn0025742#orthology", "database": "AGR" }, { "id": "RGD:1306569", "url": "https://alliancegenome.org/gene/RGD:1306569#orthology", "database": "AGR" }, { "id": "SGD:S000003871", "url": "https://alliancegenome.org/gene/SGD:S000003871#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3Q2-1", "protein_name": "phosphatidylinositol-3,5-bisphosphate 3-phosphatase", "gene_name": "Mtmr4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEEGPPSLEYIQAKDLFPPKELVKEEENLQVPFTVLQGEGVEFLGRAADALIAISNYRLHIKFKDSVINVPLRMIDSVESRDMFQLHIACKDSKVVRCHFSTFKQCQEWLSRLSRATARPAKPEDLFAFAYHAWCLGLTEEDQHTHLCQPGEHIRCRQEAELARMGFDLQNVWRVSHINSNYKLCPSYPQKLLVPVWITDKELENVASFRSWKRIPVVVYRHLRNGAAIARCSQPEISWWGWRNADDEYLVTSIAKACALDPGTRASGGSLSAGTNDASEACDTDFDSSLTACSGVESTAAPQKLLILDARSYTAAVANRAKGGGCECEEYYPNCEVVFMGMANIHAIRNSFQYLRAVCSQMPDPSNWLSALESTKWLQHLSVMLKAAVLVANTVDREGRPVLVHCSDGWDRTPQIVALAKILLDPYYRTLEGFQVLVESDWLDFGHKFGDRCGHQENAEDQNEQCPVFLQWLDSVHQLLKQFPCLFEFNEAFLVKLVQHTYSCLYGTFLANNPCEREKRNIYKRTCSVWALLRAGNKNFHNFLYTPGSDMVLHPVCHVRALHLWTAVYLPASSPCTLGEENMDLYLSPVAQSQEFSGRSLDRLPKTRSMDDLLSACDTSSPLTRTSSDPNLNNHCQEVRVSLEPWHSNPEGAEAVIESGVGSPQLTVGDVGLPPPLPSSQKDYLSNKPFKGHKSCSLSYKLLNTSVSWEMKNTSEIKVLEETEALAPGPPAREEQSRTSDGLGKPPEQCPEKEATSSLSNVSSKCGGACDFPGEPPQDSFTGTPQQPHLDSMQAVPIRCTPDHGQGSLCNPPSAASQTLQEPNTDLISQDPPGSMAGISYQEQPSSVSDLIYKKEDAGKRGSKNGQLVENPRFGKMPLELARKPISQSQISEFSFLGSNWDSFQGMMTSFPSGETTPRRLLAYGCCSKRPSNKHIRAAAPCFGGQWAQREGMKSPVCSSHSNGHCTGPGGKNNRMWFSSHPKQVSSTKPSLLSCPSPVPPLYLDDDGLPFPTDVIQHRLRQIEAGYKQEVEQLRRQVRELQMRLDIRHCCAPPAEPPMDYEDDFTCLKESDGSDTEDFGSDHSEDCLSEASWEPVDKKETEVTRWVPDHMASHCYNCDCEFWLAKRRHHCRNCGNVFCAGCCHLKLPIPDQQLYDPVLVCNSCYEHIQVSRARELMSQHLKKPIATASS", "length": 1191 }, "evidence": [ { "id": "SGD:S000003871", "url": "https://alliancegenome.org/gene/SGD:S000003871#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AEZ2-1", "protein_name": "Myotubularin related protein 7", "gene_name": "Mtmr7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEHIRTPKVENVRLVDRVSCKKAALGTLYLTATHVIFVENAPDTRKETWILHSQISTIEKQATTATGCPLLIRCKNFQIVQLVIPQERDCHDVYVSLIRLARPVRYEELYCFSFNPKLDKEEREQGWLLVDLSEEYKRMGLPDNYWQLSDVNRDYRVCDSYPTELYVPRSATAHIIVGSSKFRSRRRFPALSYYCKESHASICRSSQPLSGFSARCLEDEQMLQAIRKANPRSDFIYVVDTRPKLNAMANRAAGKGYENEDNYSNIKFQFIGIENIHVMRNSLQKMLEVCELKSPSMSDFLWGLENSGWLRHIKAIMDAGIFIAKAVSEEGTSVLVHCSDGWDRTAQVCSVASLLLDPYYRTLKGFMVLIEKDWISFGHKFNHRYGNLDGDPKEISPVIDQFIECVWQLMEQFPCAFEFNERFLIHIQHHVYSCQFGNFLCNSQKERRELKIQERTYSLWSNLWKNRADYLNPLFRADHSQTQGSLHLPTAPYNFTYKFWNGMYNRFEKGLQPRQSVTDYLMAVKEESQQLEEELESLEERLEKIQKVHLNGAKVKSKQSEPSKHSGFSTSDNSTANTPQDYSGNMKSFPSRSPSQGDEDSALILTQDNLKSSDPDLSVNSDQESGVEDLSCRSPSGGEHAPSEDSGKDRDSDEAVFLTA", "length": 660 }, "evidence": [ { "id": "SGD:S000003871", "url": "https://alliancegenome.org/gene/SGD:S000003871#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M1N853-1", "protein_name": "Myotubularin", "gene_name": "mtm1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTFRRGSGFHLRLLRENSRLNAALESCRKVNAVMASAPIAPYNSSPLGNSSSQNASRESLKMEPLADVTLLPGEERVIDKDIIYICPYNAAVKGKVFITNYRLYFKNTDSETPVTLNIPLGVISRVEKMGGASSRGENSYGLEITCKDMRNLRFALKQEGHSRRDIFEIIFKYAFPLSHGMQLFAFLSQEKYEENGWNVYEALEEYRRQGLPNNEWRVTFINKNYELCDTYPTILVVPYKATEDDLRKVATFRSRCRIPVMSWFHKENHAVITRCSQPLVGMSGKRNKDDERYLDLIREANGTTKLTIYDARPNVNAVANKATGGGYEGDDAYQNAELVFLDIHNIHVMRESLKKLKDIVYPNVEESHWLSSLESTHWLEHIKLVLSGAIQVADKVSSGSSVMVHCSDGWDRTAQLTSLSMLMLDSYYRTLRGFQVLMEKEWISFGHKFASRIGHGDKNHADQDRSPIFLQFIDCVWQMTKQFPTAFEFNERLLVVILDHLYSCRFGTFLYNCESVRDSNNVRTKTVSLWSYINSDTSLYINPFYTPESSRVLYPVASMRHLELWVTYYIRWNPRIQHQQQSPVEQRYKELLALRDQYLKKLEELQLSDSAPSSTHLTNSSTPNAATPNQHITHLQTPF", "length": 639 }, "evidence": [ { "id": "MGI:1099452", "url": "https://alliancegenome.org/gene/MGI:1099452#orthology", "database": "AGR" }, { "id": "HGNC:7448", "url": "https://alliancegenome.org/gene/HGNC:7448#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-051113-128", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-051113-128#orthology", "database": "AGR" }, { "id": "FB:FBgn0025742", "url": "https://alliancegenome.org/gene/FB:FBgn0025742#orthology", "database": "AGR" }, { "id": "RGD:1304582", "url": "https://alliancegenome.org/gene/RGD:1304582#orthology", "database": "AGR" }, { "id": "SGD:S000003871", "url": "https://alliancegenome.org/gene/SGD:S000003871#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M2BFN3-1", "protein_name": "Myotubularin-related protein 7b isoform X1", "gene_name": "mtmr7b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEHIRTPKVENVRMIDRRTPRKATVGTLYLSSTHTIFVENSEARKETWVLHSLVSNVERLPTNPSGSPVIIRCKNLIVYRLLIPQEKDSLDVVASLTRLSRPERYGELFCFSFNPNLDKELREKAWGFMDLKAEFNRMGIPSNLWHVTAANHEYRLCDTYPSELFVPKSASPAVIVGSAKFRSRGRLPVLSYFHRDTSASICRSSQPLSGFSARSSDDEQMLQAIMKSNPVSEFMYVVDTRPKLNAMANRAAGKGYENEDHYTNIKLQFIGIENIHVMRNSQQKLIDVGDMAAPSMADFLWGLENSGWLKHIKAVLDAGVFIAKAVAEDGVSVLVHCSDGWDRTAQACSVASVLLDPYYRTIKGLMVLIEKDWVSFGHKFSHRYAHLDGDPKEVSPVMDQFLECVWQLMQQFPCAFEFNERFLIQLHMLIYSCQYGNFIGNCQKERRDLKLQERTHSLWPHLWENRAEYTNPLYRTDHSQTQGVLRPLTTAYCFKFWKGMYGRAERSLSSQQSPADCLNAVREESQQLEEELTAHQERLAQLKEKKTSGERKKISRLSESARRPTPNEGELDSPQDYFSTPRGEKHTPSFTLPLDLAAQTKNGDPDDLSTCSDLESGVADLSSHSSSAGDDNKDPDSEEVVKIPA", "length": 645 }, "evidence": [ { "id": "SGD:S000003871", "url": "https://alliancegenome.org/gene/SGD:S000003871#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9Q3D0-1", "protein_name": "phosphatidylinositol-3,5-bisphosphate 3-phosphatase", "gene_name": "mtmr3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEEEGQQSLECIQANQIFPRKPPVLEEEDLQVPFPELHGEFTEYVGRAEDAVIAMSSYRLHIKFKESVVNNCSCEVSVPLQLIECVECRDMFQLHITCKDCKIIRCQFSTFEQCQEWLKRLTAAVRPPSRIEELFSFAFHAWCVDLYTGEKEQHGDLCRPGDHVMSRFHNEVERMGFDTQNAWRVSEINNKYKLCSSYPQLLLVPAWITDKELENVAAFRSWKRIPAVVYRHQSTGAVIARCGQPEVSWWGWRNADDEHLVQSIARACAVDSSSCKGVSNGSLSREYTNGADLSDVDFESSMTNSSEVETLAIQPRKLLILDARSYAAAVANRAKGGGCECPEYYPNCEVVFMGMANIHSIRKSFQSLRFLCTQMPDPANWLSALESTKWLQHLSLLLKASLLVSNAVDRDHRPVLVHCSDGWDRTPQIVALAKLLLDPYYRTIEGFQVLVETEWLDFGHKFADRCGHGENAEDLNERCPVFLQWLDCVHQLQRQFPCSFEFNEAFLVKLVQHTYSCLFGTFLCNSGKEREDRRIQERTCSVWSLLRAANRSFGNMLYSSHSETVLHPVCHVRNLMLWTAVYLPSSSPTTPSDDSCAPYPAPGANPEDQPLGRRPKTRSFDNLPSACEVGNPLTSNRRSSDPSLNEKWQDHRRSLELNIGAGTDGAASPEPDERVNGQTMVGIMGTFSNGGTENGEGLKDVRLPMIDGVDEAELTVGVAVGQMENILQEATKDESAPDTRSVAKPNETSAVNGKTDDIAQEGRTEDDLESKSLEDGNVNGHCSEDGNSEASSALSQDTSESQDSEEIEKCTTQEDDSSCNPTILTPNGLRTLTNGHGVEPSIEQAEKRLSLLESSTETLTEDLGVRPESLAPLSIPPPLKALAESSCLKQGLRTAARTLNNTPKRASLSAFPPASTDLLHPMCNGDSPDPEPSTPRTNGERATLSRQVSLASCGSLTLHARGTCSHHRCLHLGFLGRPSFSPPEPPSSSSRSHLDDDGLTLHTDAIQQRLRQIEAGHQLEVEALKRQVQELWSRLESHQAAGMLRLNGDIGDEVTSITDSDFNLEPNCLSRCSTELFSEASWEQVDKQDTEVTRWYPDHLAAQCYGCERGFWLATRKHHCRGKERMEEVWNCGNVFCGSCCDQKIPVPSQQLFEPSRVCRSCFSNLQPPAPPLDLELDKPITASSN", "length": 1186 }, "evidence": [ { "id": "SGD:S000003871", "url": "https://alliancegenome.org/gene/SGD:S000003871#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0Y5P7-1", "protein_name": "Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR2", "gene_name": "MTMR2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEESSSCESLGAGRAVAARPPSGDSLSSASTSQSDHSAHTKSASLVSSDSVSTSADNFSPDLRVLRETNKLAEMEEPPLLPGETIKDMAKDVTYICPFTGAIRGTLTVTNYRLYFKSMERDPPFVLDASLGVINRVEKIGGASSRGENSYGLEIVCKDIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNNLPLFAFEYKEVFPENGWKVYDPIWEYRRQGIPNESWRLSKINERYELCDTYPAILAVPVNIPDEELKRVASFRSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYPNIEETHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLSLLMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITILDHLYSCLFGTFLCSSEQQRVKESLPKKTVSLWSYINSQLEDFTNPLYVSYSNHVLYPVASMRHLELWVGYYIRWNPRMKPQEPVHNRYKELLAKRAELQKKVEELQREITNRSTSSSERAGSPAQCVTPVQTVV", "length": 644 }, "evidence": [ { "id": "Q9VMI9", "url": "https://omabrowser.org/oma/group/Q9VMI9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0AB32TRB3-1", "protein_name": "phosphatidylinositol-3,5-bisphosphate 3-phosphatase", "gene_name": "mtmr4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSRSVSCSMLNCFGEEGPPSLEYIQARDLFPQKELLKEDDTLQVPFPVLQGEWVEFLGRADDAVIAISNYRLHIKFKDSIINMFPGVDSEMSVPLRLIESVESRDMFQLHIICKDSKVVRCHFSTFKQCEEWLKRLQRAITHPARLEELFALAYHAWCLGANTDDEDQHLHLCRPGDHVRHRLEVEVKRMGFDMQNAWRVSDINTNYKLCSSYPQKLLVPVWITDKELESVASFRSWKRIPVVVYRHQRNGAVIARCSQPEISWWGWRNTEDEYLVTSIAKACQLDGGSRAGRSRGDGPDSDSDFDSSLTGCPAPDSSAAAQKLLILDARSYTAAVANRAKGGGCECEEYYPNCEVMFMGMANIHSIRNSFQSLRAVCSQIPDPGNWLSALESTRWLQHLSVMLKAASLVCSALERDGRPVLVHCSDGWDRTPQIVALAKILLDPFYRTIEGFQVLVETEWLDFGHKFADRCGHQENGDDVSEQCPVFLQWLDCVHQLLKQFPCLFEFNEAFLVKLVQHTYSCLYGTFLCNNGKERETRNVYKRTCSIWSLLRTGNKNFQNFLYIPCHDMVLQPVCHTRALQLWTAVYLPSSSPCTAAEDAVEVYLSPGAGDREEFSSRSLDRLPKTRSMDNLLSACENGVTLTRTSSDPNLNKHCPEGRPSLEPNPPLILAPDAGALREELENHQSLPSEQLEDDQGVEPCLTTQPLPSIPRPLAIEQAPPPLISNQSPPQITHSPLPPSDVHVRTAEITSTASLCNGFAHVENTRESSSDSVETLTEQSVCVEVKKPDEVRNGALVLLRERPHAVEYAKTARRLISTSPLPDLSLLGSQWDSVQGMVQSACGGAIQHGSYHGRRLANKLLRAQAGSSVGGGPCCHRDPLRAPGSPIQSGWFSAVKSSGYAALCSSSLGPSLRQLLPSHSCPSAGSSAYLDDDGLPVALDAVQQRLRQIEASYKQEVEVLRRQVRQLQLKLESKQFCTPPSEPDVDYEDDITCLRESDGSEDSDSLSSRSEDRFSEGSWDRVERKDTEVTRWVPDHMASHCFNCDCEFWIAKRRHHCRNCGNVFCKDCCHLKLPIPDQQLYDPVLVCNTCYDLLLESRTRELRSQQLKKAIATASS", "length": 1117 }, "evidence": [ { "id": "SGD:S000003871", "url": "https://alliancegenome.org/gene/SGD:S000003871#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58FYQ3-1", "protein_name": "phosphatidylinositol-3,5-bisphosphate 3-phosphatase", "gene_name": "mtmr1a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEKQQQHHPSGSESPVLPPVARKPRNLGVNPASRQDSVDSLDSPTGSHVEWCKQLIAATISSQITSGVPSESIHRESKIGKKIDTRVSKRPNFRSQDSGEDGCQFDSDCELPSHTSQVFRDVRRPAPMDEVPLVPGETIKTTVKDVMYICPFTGAVTGTLTITDYKLYFVSLERDAPFILDVNLGAISRLETISVQSLGENTSGMEIVCKDMRSPRFAYKKEEQSKLEILETLTKYAFPLSNELSLFAFQYKEQFPEDGWKVYDPVAEYKRMGLPNESWSISKINSNYEVCDTYPALLVTPTSIKEDEIRRVASFRVKHRIPVLSWIHPETQATIVRCSQPMVGPTDRRCKEDEHYLQTIMDANAQSHKLAIFDARQNTVAHNHKTKDGGYENENFYPNMELNFLEIPNIHVMRESLRKLKEVVYPTIEEQRWHSAIDATHWLEYIRLLLAGAVRIADKVESSKSSVVVHCSDGWDRTAQLTSLSMLMLDSYYRTLRGFQVLLEKEWISFGHKFAARIGHGDENHANSERSPLFVQFIDCVWQMMRQFPSAFEFNELFLITILDYLYSCLFGTFLYNSEQERVEKEVNRKTVSLWSYINSQSEDFTNPFYVDYENHVLYPLASLRHLELWVGYYVRWNPRMRPQMPVHQNLKELLYLRAELQRKVEELQKDVSSSRSVSSSSEHAYSPSHGGTPLHSSV", "length": 699 }, "evidence": [ { "id": "MGI:1858271", "url": "https://alliancegenome.org/gene/MGI:1858271#orthology", "database": "AGR" }, { "id": "HGNC:7449", "url": "https://alliancegenome.org/gene/HGNC:7449#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050522-518", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-518#orthology", "database": "AGR" }, { "id": "FB:FBgn0025742", "url": "https://alliancegenome.org/gene/FB:FBgn0025742#orthology", "database": "AGR" }, { "id": "RGD:1306569", "url": "https://alliancegenome.org/gene/RGD:1306569#orthology", "database": "AGR" }, { "id": "SGD:S000003871", "url": "https://alliancegenome.org/gene/SGD:S000003871#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58HN56-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "zgc:154055", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MELSSEHIKTANVEDVTLRRPFHPALRGTLCVTSHHLLFSDRKDEASWQLLLLLKNIDAIEKSVENLFGYPRAVGQSSGTITIKCKDLLVLQLEIPGMEECLNIASSIEALSSLESVTEMYPFFYRPSHLALHGPWGLSSTEQYYKQTERLWDKWRVSTVNSDYSVCPSYPSAVIVPREVDDDKLVRSARFRQGSRFPVLSYCHHRNRMVIMRSSQPLTGANRKRCREDELVLQAVIDGSEMGYIIDLRSAQQAQQARMTGGGFESKSSYNNWKRIHRHHERGKVLQESLIKLVEACGDQSHSVDRWLSKLENSKWLSHVHSALSTAGLVAECVERDAHSVLVHGSEGTDNTLLVSSLAQLILDPASRSLSGFLCLLERDWIQAGHPFQLRCVHSAYSHARLKQECPTFLLLLDCVWQVWRQFPLAMEFSEALLLRLAQEVYASDYGTFLCNSEQERYAAGVKEKTHCLFQALLKPDIDEQYLNPLYEPTDLAIWPSVHPQSLQLWTGLFLRWTEYAQNMEEAREEVWSIVKEHKERAGSDRTKNNNTSTHCDTLTPFENLMDELTIL", "length": 568 }, "evidence": [ { "id": "SGD:S000003871", "url": "https://alliancegenome.org/gene/SGD:S000003871#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58I8Q3-1", "protein_name": "phosphatidylinositol-3,5-bisphosphate 3-phosphatase", "gene_name": "mtmr1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDKRPTSPQSNAETPDSPTGAHVEWCKQLIAATMSSQSCGPISSEMISREYKDCDMEVKGFLLDSDPQQTAPSSALREGNKQAQMEEAPRIPGETIKAIVKDVMYICPFSGVIRGTLTITDFKLYFKSLTRVNSLLKLSSGDSPFVLDVNLGAVSRLESIAVQSHGDDTQGLEIVCKDLRTPRFAYKKEGQSNLEMFKILSKYAFPLSHNLPLFAFKYRETFPEDGWKIYDPVAEYKRQGLPNESWIISKVNSGYEVCETYPALLVLPSNVTEDELKRVAAFRAKRRFPVLSWIHPESQAAIVRCGQPQVGPSDRRCREDERYLQTILDANAQSHKLCIFDARQSTVADTNKAKDGGYENESFYINVELNFLEIPNIHVMRESLRKLKEVVYPAIDQQHWFSNVDATHWLEYVRLLLAGAVRIADRIESGKTSVVVHCSDGWDRTAQLTSLAMLMLDAHYRSLKGFQVLLEKEWLSFGHRFASRVGHGDGNHANSERSPLFVQFIDCVWQMTRQFPSAFEFNELFLITVLDHLFSCLFGTFLYNSEQERVSKEVYNKTVSLWSYVNSQIEEFTNPLYVNYEHHVLYPIASLRHLELWVSYYVRWNPRMRPQVPIHQSLKELLVLKSELQKRVEDLKQDAASSNSLSSSEHEGMPMQTTV", "length": 659 }, "evidence": [ { "id": "MGI:1858271", "url": "https://alliancegenome.org/gene/MGI:1858271#orthology", "database": "AGR" }, { "id": "HGNC:7449", "url": "https://alliancegenome.org/gene/HGNC:7449#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050327-48", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050327-48#orthology", "database": "AGR" }, { "id": "FB:FBgn0025742", "url": "https://alliancegenome.org/gene/FB:FBgn0025742#orthology", "database": "AGR" }, { "id": "RGD:1306569", "url": "https://alliancegenome.org/gene/RGD:1306569#orthology", "database": "AGR" }, { "id": "SGD:S000003871", "url": "https://alliancegenome.org/gene/SGD:S000003871#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0JMK5-1", "protein_name": "Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR2", "gene_name": "mtmr2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEESASVDSVESLCSSTTTRSDRSSGPKVSDTELRSKGRPIEKMYKDPSKGELPLLPVELVQESAKDVTYICPFIGPIRGSLTVTNYRLFFRCTDREPVFGLDLPLGVLSRVEKIGAATGRGDVSYGLACKDMRNLRFVHKEPDDSLKKSVFEVLMKFAFPVSNNMSLFAFEYKQVFPENGWKVYDPLAECKRQGLPNESWRISKLNDHYELCDSYPATLVVPVTITDDELRRVSSFRAKGRIPVLSWIHPESQAAVVRSSQPMVGQNGRRCKEDEKLLQAIMDANAQSHKLFIFDARPSVNAAANKMKGGGFESEDAYQNAELVFLDIHNIHVMRESLRKLKEVVYPNIEESHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLALIMLDSHYRTIRGFQILVEKEWLSFGHRFQQRVGHGDKNHTDVDRSPIFLQFIDCVWQMTRQFPAAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRLKEEIPKRTVSLWSFVNSQLEEFVNPLYVHYSSHVLFPTVGIRHLQLWVSYYIRWNPRMRPQEPVHQRYKELLAKRAELQKRVEELQREVSSRTASSSSERAGSPTRSITPVQTFV", "length": 620 }, "evidence": [ { "id": "MGI:1924366", "url": "https://alliancegenome.org/gene/MGI:1924366#orthology", "database": "AGR" }, { "id": "HGNC:7450", "url": "https://alliancegenome.org/gene/HGNC:7450#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-990715-14", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-990715-14#orthology", "database": "AGR" }, { "id": "FB:FBgn0025742", "url": "https://alliancegenome.org/gene/FB:FBgn0025742#orthology", "database": "AGR" }, { "id": "RGD:1311865", "url": "https://alliancegenome.org/gene/RGD:1311865#orthology", "database": "AGR" }, { "id": "SGD:S000003871", "url": "https://alliancegenome.org/gene/SGD:S000003871#orthology", "database": "AGR" }, { "id": "Q9VMI9", "url": "https://omabrowser.org/oma/group/Q9VMI9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A6QLT2-1", "protein_name": "Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR2", "gene_name": "MTMR2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEKSSSCESLGSQPAVARPPSVDSLSSASTSHSENSVHTKSASVVSSDSISTSAENFSPDLRVLRESNKLAEMEEPPLLPGENIKDMAKDVTYICPFTGAVRGTLTVTNYRLYFKSMERDPPFVLDASLGVISRVEKIGGASSRGENSYGLETVCKDIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNNLSLFAFEYKEVFPENGWKLYDSLSEYRRQGIPNESWRITKVNERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYPNIEETHWLSNLESTHWLEHIKLILAGALRIADRVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKENLPRRTVSLWSYINSQLEDFTNPLYGSYSNHVLYPVASMRHLELWVGYYVRWNPRMKPQEPIHNRYKELLAKRAELQKKVEELQREISNRSTSSSERAGSPAQCVTPVQTVV", "length": 643 }, "evidence": [ { "id": "Q9VMI9", "url": "https://omabrowser.org/oma/group/Q9VMI9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZA31-1", "protein_name": "Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR2", "gene_name": "Mtmr2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEEPALLPGENIKDMAKDVTYICPFTGAVRGTLTVTNYRLYFKSMERDPPFVLDASLGVISRVEKIGGASSRGENSYGLETVCKDIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNGLPLFAFEYKEVFPENGWKLYDPLLEYRRQGIPNESWRITKVNERYELCDTYPALLAVPANIPDEELKRVASFRSRGRIPVLSWIHPESQATVTRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYPNIEETHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKENLPKKTVSLWSYINSQLEDFTNPLFGSYSNHVLYPVASMRHLELWVGYYIRWNPRMKPQEPIHSRYKELLAKRTELQRKVEELQREISNRSTSSSERASSPAQCVTPVQTVV", "length": 571 }, "evidence": [ { "id": "MGI:1924366", "url": "https://alliancegenome.org/gene/MGI:1924366#orthology", "database": "AGR" }, { "id": "HGNC:7450", "url": "https://alliancegenome.org/gene/HGNC:7450#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-990715-14", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-990715-14#orthology", "database": "AGR" }, { "id": "FB:FBgn0025742", "url": "https://alliancegenome.org/gene/FB:FBgn0025742#orthology", "database": "AGR" }, { "id": "RGD:1311865", "url": "https://alliancegenome.org/gene/RGD:1311865#orthology", "database": "AGR" }, { "id": "SGD:S000003871", "url": "https://alliancegenome.org/gene/SGD:S000003871#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P47147-1", "protein_name": "Phosphoinositide 3-phosphatase", "gene_name": "YMR1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MEYIKIAKVSNVVLHRRGTATQGTLHLTTHHLIFESPQLSTEFWFPYPLIYGVHKNPGSTLLSKLTSTNQIQLEGTDSQNYKLYQGKDLWSFVNIKVIGKDYAVFSLDFGGDLHLQARKVYDSILNLTVLSNITQLYAFIYISNNLERKLPSPDSWDIYDPIKEFRRQGLDSKDETCPWRLSTVNEHYEFCPTYPSKLFVPRSTSDILLKHASKFRSQKRIPVLTYHHKATDCNILRSSQPLPGLINQRSIQDEKLVWESFNSFCNKDIRRTKHVIVDARPRTNALAQMALGGGTENMDNYNFFLADNNMGVDKSLKLPTVTRLFLGIDNIHIVSNTAAYMTEVICQGGDLNLPLEQNLIRSQKFSNWLKLNTLILKSVDMLLKSIIFNHSNVLVHCSDGWDRTSQVVSLLEICLDPFYRTFEGFMILVEKDWCSFGHRFLERSGHLNSDIRFHDNTMHSNFNDVDTNGDDLDIGVNTQDDYAEDDEGGEDETNLINLSRISKKFNENFKLNKKSLKFVSPVFQQFLDCVYQLLTQNPDLFEFNERFLRRLVYHLYSCQYGTFLSNSEKEKFQQNLPNKTKSVWDYFRSRRKQFINPNFIQRKRSGMNEHDQNLEEEEKVEWISPDLKKVQWWWQLYGRKDSEMNDELRHKRDSVPISVDKKSKEHSNSDGGKGLNLSIFGFDMFNRK", "length": 688 }, "evidence": [ { "id": "MGI:1858271", "url": "https://alliancegenome.org/gene/MGI:1858271#orthology", "database": "AGR" }, { "id": "MGI:1924366", "url": "https://alliancegenome.org/gene/MGI:1924366#orthology", "database": "AGR" }, { "id": "MGI:1099452", "url": "https://alliancegenome.org/gene/MGI:1099452#orthology", "database": "AGR" }, { "id": "HGNC:7450", "url": "https://alliancegenome.org/gene/HGNC:7450#orthology", "database": "AGR" }, { "id": "HGNC:7449", "url": "https://alliancegenome.org/gene/HGNC:7449#orthology", "database": "AGR" }, { "id": "HGNC:7448", "url": "https://alliancegenome.org/gene/HGNC:7448#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-990715-14", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-990715-14#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050522-518", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-518#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-051113-128", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-051113-128#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050327-48", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050327-48#orthology", "database": "AGR" }, { "id": "FB:FBgn0025742", "url": "https://alliancegenome.org/gene/FB:FBgn0025742#orthology", "database": "AGR" }, { "id": "RGD:1304582", "url": "https://alliancegenome.org/gene/RGD:1304582#orthology", "database": "AGR" }, { "id": "RGD:1306569", "url": "https://alliancegenome.org/gene/RGD:1306569#orthology", "database": "AGR" }, { "id": "RGD:1311865", "url": "https://alliancegenome.org/gene/RGD:1311865#orthology", "database": "AGR" }, { "id": "SGD:S000003871", "url": "https://alliancegenome.org/gene/SGD:S000003871#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q13496-1", "protein_name": "Myotubularin", "gene_name": "MTM1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASASTSKYNSHSLENESIKRTSRDGVNRDLTEAVPRLPGETLITDKEVIYICPFNGPIKGRVYITNYRLYLRSLETDSSLILDVPLGVISRIEKMGGATSRGENSYGLDITCKDMRNLRFALKQEGHSRRDMFEILTRYAFPLAHSLPLFAFLNEEKFNVDGWTVYNPVEEYRRQGLPNHHWRITFINKCYELCDTYPALLVVPYRASDDDLRRVATFRSRNRIPVLSWIHPENKTVIVRCSQPLVGMSGKRNKDDEKYLDVIRETNKQISKLTIYDARPSVNAVANKATGGGYESDDAYHNAELFFLDIHNIHVMRESLKKVKDIVYPNVEESHWLSSLESTHWLEHIKLVLTGAIQVADKVSSGKSSVLVHCSDGWDRTAQLTSLAMLMLDSFYRSIEGFEILVQKEWISFGHKFASRIGHGDKNHTDADRSPIFLQFIDCVWQMSKQFPTAFEFNEQFLIIILDHLYSCRFGTFLFNCESARERQKVTERTVSLWSLINSNKEKFKNPFYTKEINRVLYPVASMRHLELWVNYYIRWNPRIKQQQPNPVEQRYMELLALRDEYIKRLEELQLANSAKLSDPPTSPSSPSQMMPHVQTHF", "length": 603 }, "evidence": [ { "id": "MGI:1099452", "url": "https://alliancegenome.org/gene/MGI:1099452#orthology", "database": "AGR" }, { "id": "HGNC:7448", "url": "https://alliancegenome.org/gene/HGNC:7448#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-051113-128", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-051113-128#orthology", "database": "AGR" }, { "id": "FB:FBgn0025742", "url": "https://alliancegenome.org/gene/FB:FBgn0025742#orthology", "database": "AGR" }, { "id": "RGD:1304582", "url": "https://alliancegenome.org/gene/RGD:1304582#orthology", "database": "AGR" }, { "id": "SGD:S000003871", "url": "https://alliancegenome.org/gene/SGD:S000003871#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q13613-1", "protein_name": "Phosphatidylinositol-3-phosphate phosphatase MTMR1", "gene_name": "MTMR1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDRPAAAAAAGCEGGGGPNPGPAGGRRPPRAAGGATAGSRQPSVETLDSPTGSHVEWCKQLIAATISSQISGSVTSENVSRDYKALRDGNKLAQMEEAPLFPGESIKAIVKDVMYICPFMGAVSGTLTVTDFKLYFKNVERDPHFILDVPLGVISRVEKIGAQSHGDNSCGIEIVCKDMRNLRLAYKQEEQSKLGIFENLNKHAFPLSNGQALFAFSYKEKFPINGWKVYDPVSEYKRQGLPNESWKISKINSNYEFCDTYPAIIVVPTSVKDDDLSKVAAFRAKGRVPVLSWIHPESQATITRCSQPLVGPNDKRCKEDEKYLQTIMDANAQSHKLIIFDARQNSVADTNKTKGGGYESESAYPNAELVFLEIHNIHVMRESLRKLKEIVYPSIDEARWLSNVDGTHWLEYIRMLLAGAVRIADKIESGKTSVVVHCSDGWDRTAQLTSLAMLMLDSYYRTIKGFETLVEKEWISFGHRFALRVGHGNDNHADADRSPIFLQFVDCVWQMTRQFPSAFEFNELFLITILDHLYSCLFGTFLCNCEQQRFKEDVYTKTISLWSYINSQLDEFSNPFFVNYENHVLYPVASLSHLELWVNYYVRWNPRMRPQMPIHQNLKELLAVRAELQKRVEGLQREVATRAVSSSSERGSSPSHSATSVHTSV", "length": 665 }, "evidence": [ { "id": "MGI:1858271", "url": "https://alliancegenome.org/gene/MGI:1858271#orthology", "database": "AGR" }, { "id": "HGNC:7449", "url": "https://alliancegenome.org/gene/HGNC:7449#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050522-518", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-518#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050327-48", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050327-48#orthology", "database": "AGR" }, { "id": "FB:FBgn0025742", "url": "https://alliancegenome.org/gene/FB:FBgn0025742#orthology", "database": "AGR" }, { "id": "RGD:1306569", "url": "https://alliancegenome.org/gene/RGD:1306569#orthology", "database": "AGR" }, { "id": "SGD:S000003871", "url": "https://alliancegenome.org/gene/SGD:S000003871#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q13614-1", "protein_name": "Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR2", "gene_name": "MTMR2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEKSSSCESLGSQPAAARPPSVDSLSSASTSHSENSVHTKSASVVSSDSISTSADNFSPDLRVLRESNKLAEMEEPPLLPGENIKDMAKDVTYICPFTGAVRGTLTVTNYRLYFKSMERDPPFVLDASLGVINRVEKIGGASSRGENSYGLETVCKDIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNNLPLFAFEYKEVFPENGWKLYDPLLEYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYPNIEETHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFTNPLYGSYSNHVLYPVASMRHLELWVGYYIRWNPRMKPQEPIHNRYKELLAKRAELQKKVEELQREISNRSTSSSERASSPAQCVTPVQTVV", "length": 643 }, "evidence": [ { "id": "MGI:1924366", "url": "https://alliancegenome.org/gene/MGI:1924366#orthology", "database": "AGR" }, { "id": "HGNC:7450", "url": "https://alliancegenome.org/gene/HGNC:7450#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-990715-14", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-990715-14#orthology", "database": "AGR" }, { "id": "FB:FBgn0025742", "url": "https://alliancegenome.org/gene/FB:FBgn0025742#orthology", "database": "AGR" }, { "id": "RGD:1311865", "url": "https://alliancegenome.org/gene/RGD:1311865#orthology", "database": "AGR" }, { "id": "SGD:S000003871", "url": "https://alliancegenome.org/gene/SGD:S000003871#orthology", "database": "AGR" }, { "id": "Q9VMI9", "url": "https://omabrowser.org/oma/group/Q9VMI9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q13615-1", "protein_name": "Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR3", "gene_name": "MTMR3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDEETRHSLECIQANQIFPRKQLIREDENLQVPFLELHGESTEFVGRAEDAIIALSNYRLHIKFKESLVNVPLQLIESVECRDIFQLHLTCKDCKVIRCQFSTFEQCQEWLKRLNNAIRPPAKIEDLFSFAYHAWCMEVYASEKEQHGDLCRPGEHVTSRFKNEVERMGFDMNNAWRISNINEKYKLCGSYPQELIVPAWITDKELESVSSFRSWKRIPAVIYRHQSNGAVIARCGQPEVSWWGWRNADDEHLVQSVAKACASDSRSSGSKLSTRNTSRDFPNGGDLSDVEFDSSLSNASGAESLAIQPQKLLILDARSYAAAVANRAKGGGCECPEYYPNCEVVFMGMANIHSIRRSFQSLRLLCTQMPDPGNWLSALESTKWLHHLSVLLKSALLVVHAVDQDQRPVLVHCSDGWDRTPQIVALAKLLLDPYYRTIEGFQVLVEMEWLDFGHKFADRCGHGENSDDLNERCPVFLQWLDCVHQLQRQFPCSFEFNEAFLVKLVQHTYSCLFGTFLCNNAKERGEKHTQERTCSVWSLLRAGNKAFKNLLYSSQSEAVLYPVCHVRNLMLWSAVYLPCPSPTTPVDDSCAPYPAPGTSPDDPPLSRLPKTRSYDNLTTACDNTVPLASRRCSDPSLNEKWQEHRRSLELSSLAGPGEDPLSADSLGKPTRVPGGAELSVAAGVAEGQMENILQEATKEESGVEEPAHRAGIEIQEGKEDPLLEKESRRKTPEASAIGLHQDPELGDAALRSHLDMSWPLFSQGISEQQSGLSVLLSSLQVPPRGEDSLEVPVEQFRIEEIAEGREEAVLPIPVDAKVGYGTSQSCSLLPSQVPFETRGPNVDSSTDMLVEDKVKSVSGPQGHHRSCLVNSGKDRLPQTMEPSPSETSLVERPQVGSVVHRTSLGSTLSLTRSPCALPLAECKEGLVCNGAPETENRASEQPPGLSTLQMYPTPNGHCANGEAGRSKDSLSRQLSAMSCSSAHLHSRNLHHKWLHSHSGRPSATSSPDQPSRSHLDDDGMSVYTDTIQQRLRQIESGHQQEVETLKKQVQELKSRLESQYLTSSLHFNGDFGDEVTSIPDSESNLDQNCLSRCSTEIFSEASWEQVDKQDTEMTRWLPDHLAAHCYACDSAFWLASRKHHCRNCGNVFCSSCCNQKVPVPSQQLFEPSRVCKSCYSSLHPTSSSIDLELDKPIAATSN", "length": 1198 }, "evidence": [ { "id": "SGD:S000003871", "url": "https://alliancegenome.org/gene/SGD:S000003871#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5PQT2-1", "protein_name": "Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR3", "gene_name": "Mtmr3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRHSLECIQANQIFPRKQLIREDENLQVPFLELHGESTEYVGRAEDAIIALSNYRLHIKFKESLVNVPLQLIESVECRDIFQLHLTCKDCKVIRCQFPTFEQCQDWLKRLNNAIRPPGKIEDLFSFAYHAWCMEVYASEKEQHGDLCRPGEHVTSRFKNEVERMGFDMNNAWRISNINEKYKLCGSYPQELIVPAWITDKELESVAGFRSWKRIPAVIYRHQSNGAVIARCGQPEVSWWGWRNADDEHLVQSVAKACASDSQSSVGKVSTRNSCRGFPNAGDLSDVEFDASLSNASGTESLALQPQKLLILDARSYAAAVANRAKGGGCECPEYYPNCEVVFMGMANIHSIRRSFQSLRLLCTQMPDPGNWLSALESTKWLHHLSVLLKSALLVVHAVDRDQRPVLVHCSDGWDRTPQIVALAKLLLDPYYRTVEGFQVLVEMEWLDFGHKFADRCGHGENSDDLNERCPVFLQWLDCVHQLQRQFPCSFEFNEAFLVKLVQHTYSCLFGTFLCNNAKERGEKQTQERTCSVWSLLRAGNKAFKNLLYSSQSEAVLYPVCHVRNLMLWSAVYLPCPSPSTPTDDSCAPYPAPGTSPDEPPLSRLPKTRSFDNLTTTCDNMVPLASRRSSDPSLNEKWQEHGRSLELSSFAGSGEEVPAIDSLRRPSRLLGGAELSVAAGVAEGQMENILQEATKEESGVEEPTHREHTEVPEVKEEAPLAKESRTAAQGSGVLYQEPQLDDATLRSHLGPSLSSFSQGIPEHREVGHSVLSSSLPASLRGEDSQEVPVEQPQVENIAEDRENVVPAVPVDVKIGLGTSESSPLLPSQVPFETRGPHMNNSVHMLLEDKVKSESGPQLHHRPCLASSGRFSGKDMLPIAPEPRSAERPQWDSVLHRTSSPGNTLSLMMQAPCALPLDKCRQRIVCNGALETENKASEQPAGFDTLQKYPTPNGHCANGETGRSKDSLSHQLSATSYSSAHSCSRNLHHKWLNSHSGRPSTTNSPEQPSRSHLDDDGMPVYTDTIQQRLRQIESGHQQEVETLKKQVQELKSRLESQYLTSSLRFNGDFGDEVTSIPDSESNLDQNCLSRCSTEIFSEASWEQVDKQDTEMTRWLPDHLAAHCYACDSAFWLASRKHHCRNCGNVFCSSCCNQKVPVPSQQLFEPSRVCKSCYSSLHPTSSSIDLELDKPIAATSN", "length": 1194 }, "evidence": [ { "id": "SGD:S000003871", "url": "https://alliancegenome.org/gene/SGD:S000003871#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6AXQ4-1", "protein_name": "Myotubularin", "gene_name": "Mtm1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASSSASDCDAHPVERESMRKVSQDGVRQDMSKSGPRLPGESAITDKEVIYICPFSGPVKGRLYITNYRLYLRSLETDLAPILDVPLGVISRIEKMGGVTSRGENSYGLDITCKDLRNLRFALKQEGHSRRDIFDVLTRHAFPLAYNLPLFAFVNEEKFKVDGWAIYNPVEEYRRQGLPDRHWRISFVNQRYELCDTYPALLVVPYRASDDDLRRVATFRSRNRIPVLSWIHPENRAAIMRCSQPLVGVGGKRSRDDERYLDIIRETNKQTSKLTIYDARPGVNAVANKATGGGYEGEDAYPHAELSFLDIHNIHVMRESLRRVRDIVYPHVEEAHWLSSLESTHWLEHIKLLLTGAIRVADKVASGLSSVLVHCSDGWDRTAQLTTLAMLMLDGFYRSIEGFEILVQKEWISFGHKFSSRIGHGDKNHADADRSPIFLQFIDCVWQMTKQFPTAFEFNECFLVAILDHLYSCRFGTFLLNCEAARERQRLAERTVSVWSLINSNKDEFTNPFYARESNRVIYPVTSVRHLELWVNYYIRWNPRIRQQPHPMEQRYNELLALRDDYIKKLEELQLATPTKLTDSSTPPSGSAQIAPRMQTHF", "length": 602 }, "evidence": [ { "id": "MGI:1099452", "url": "https://alliancegenome.org/gene/MGI:1099452#orthology", "database": "AGR" }, { "id": "HGNC:7448", "url": "https://alliancegenome.org/gene/HGNC:7448#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-051113-128", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-051113-128#orthology", "database": "AGR" }, { "id": "FB:FBgn0025742", "url": "https://alliancegenome.org/gene/FB:FBgn0025742#orthology", "database": "AGR" }, { "id": "RGD:1304582", "url": "https://alliancegenome.org/gene/RGD:1304582#orthology", "database": "AGR" }, { "id": "SGD:S000003871", "url": "https://alliancegenome.org/gene/SGD:S000003871#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6TEL0-1", "protein_name": "Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR8", "gene_name": "mtmr8", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEHIITPKVENVKLLNRYTEKKSALGTLYLTATHLIYVEQTSNTRKETWVLHHHILSVEKLLLTASGCPLLIRCKTFQHLHLLFQKERDCQDVYQSLLRLFQPVKEEELYAFLYNPHQNEEERRRGWELISVVNDFNRMGLSNDYWEISHINKNFEMCSTYPSILGLPKSASVATVTGSAKFRSRGRLPVLSYYHKDTKAAICRCSQPLSGLNSRCVEDEQMLQAISQANPNSPFIYVVDTRPKLNAMANRAAGKGYENEDNYSNIRFQFQGIENIHVMRSSLQKLLEVCSMKSPSMSDYLTGLENSGWLRHIKSVMDAGVFLAKAVCEERASVLVHCSDGWDRTAQVCSLACLLLDPYYRTIKGLMVLIEKEWISFGHKFSHRCGHLDSDPKEASPVFTQFLECVWQLSQQFPCVFEFNEHYLIEIHDQVYACQYGNFIGNCQKERLDMRLHEKTFSLWPHLLENQHQYRNPLYRRSLESTVLRPSTLPLHFKFWCGMYNHYDRGMHPKQSVLDTLLTLTQRQVEGERTMTELQRQLAVADGVLPDPAGPINTHADQNNQSEKMPAPPVVQSNGSCAPLINGNVKEVGPGAENSNQEDREEPAANEHDLSSKDKPVFVETEHSKEEVQESS", "length": 632 }, "evidence": [ { "id": "SGD:S000003871", "url": "https://alliancegenome.org/gene/SGD:S000003871#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8K296-1", "protein_name": "Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR3", "gene_name": "Mtmr3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDEEMRHSLECIQANQIFPRKQLIREDENLQVPFLELHGESTEYVGRAEEAIIALSNYRLHIKFKESLVNVPLQLIESVECRDIFQLHLTCKDCKVIRCQFPTFEQCQDWLKRLNNAIRPPGKIEDLFSFAYHAWCMEVYASEKEQHGDLCRPGEHVTSRFKNEVERMGFDMNNAWRISNINEKYKLCGSYPQELIVPAWITDKELESVAGFRSWKRIPAVIYRHQSNGAVIARCGQPEVSWWGWRNADDEHLVQSVARACASDSQSSISKVSTRNSCRDFPNAGDLSDVEFDSSLSNTSGAESLALQPQKLLILDARSYAAAVANRAKGGGCECPEYYPNCEVVFMGMANIHSIRRSFQSLRLLCTQMPDPGNWLSALESTKWLHHLSVLLKSALLVVHAVDRDQRPVLVHCSDGWDRTPQIVALAKLLLDPYYRTIEGFQVLVEMEWLDFGHKFADRCGHGEDSDDLNERCPVFLQWLDCVHQLQRQFPCSFEFNEAFLVKLVQHTYSCLFGTFLCNNAKERGEKQTQERTCSVWSLLRAGNKAFKNLLYSSQSEAVLYPVCHVRNLMLWSAVYLPCPSPSTPTDDSCAPYPVPGTSPDEPPLSRLPKTRSFDNLTTTCENMVPLASRRSSDPSLNEKWQEHGRSLELSSFASAGEEVPAMDSLRKPSRLLGGAELSVAAGVAEGQMENILQEATKEESGVEEPTHRGHTEVPEVKEEAPLAKESSMAAEGPVVLYQEPQLDDATLRSHQGPSLSLFSQGIPEHQDGHNVLSSSLQAPLRGEDSQEVPVEQPQVENIAEDRENVAPAVPVDAKVGLGISQSSSLLPSQVPFETRGPHINNSVHMLLEDKVKSESGPQLHHRPCPASSGRFSGKDMLPVAPEPRSAERPQWDSVLHRTSSPGNTLSLLQAPCALPLDKCRQGIVCNGALETENKASEQPAGFDTLQKYPTPNGHCANWEAGRSKDSLSHQLSATSCSSAHLYSRNLHHKWLNSHSGRPSTTSSPDQPSRSHLDDDGMPVYTDTIQQRLRQIESGHQQEVETLKKQVQELKSRLESQYLTSSLRFNGDFGDEVTSIPDSESNLDQNCVSRCSTEIFSEASWEQVDKQDTEMTRWLPDHLAAHCYACDSAFWLASRKHHCRNCGNVFCSSCCNQKVPVPSQQLFEPSRVCKSCYSSLHPTSSSIDLELDKPIAATSN", "length": 1196 }, "evidence": [ { "id": "SGD:S000003871", "url": "https://alliancegenome.org/gene/SGD:S000003871#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8MLR7-1", "protein_name": "phosphatidylinositol-3,5-bisphosphate 3-phosphatase", "gene_name": "Mtmr6", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDITRFMNKFNEIERQLSPTSALRLSFDNISPETEEPPDGNKRLWGVPVPPFVSEKVVSWIEEEFNEAPVFYNGNSVLKKVENVRMIDRYNTKNPTVGTLYLTATHLIFVEPDSNKETWILHMHVASIEKLPLSTTGSPLLIRCKTFLSVTFVIPKDSECHDVYTSLLKLFQPVSINKLYCFNYQPNKDDFPKNAGWDYFKLEAEFKHMLVPNEAWTLCSMNEKYELCDTYPRQIYVPKEATTLMLISSSRFRSKGRLPVLTYLHNNKASICRCSQPLSGFSARCLEDEQMLEAIRKTNSNTDYMYVVDTRPRINAMANRAAGKGYENEAFYENIKFHFLGIENIHVQRASLQKVLEACEQKSPTMSAFINALESSGWLKHIRSILDTSSFIANAVDKGVSVVVHCSDGWDRTAQVCSLAQLMLNPYYRTIKGFQALIEKDWLAFGHKFSERCGHIQTDAREVSPIFTQFLDCTWQLMSQRSEAFEFNERFLLILHDHVHSCQFGTFVGNCEKDRLDLKLAERTFSLWGYMANHLNEYINPLYKPNVDEAIKANLAPQCIKFWRGMYSRFESGIHPREPLGDVLLDSKEHCNSLEDHVQHLTKRIASFKNYISKSAKKLQDATSAPGKVNKELSSNEINDNKYNYDKKLSELSAADDDHPLKASNMSFASLSLSAEQSSPPQALPEEINSVAVDWKPMRNVTTCSCSTPFDQFSKKTHCWRCGDIFCERCIDKNVALPGHDSGKPVPVCRGCFRQMQKQSP", "length": 761 }, "evidence": [ { "id": "SGD:S000003871", "url": "https://alliancegenome.org/gene/SGD:S000003871#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8VE11-1", "protein_name": "Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR6", "gene_name": "Mtmr6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEHIRTTKVEQVKLLDRFSTNNKSLTGTLYLTATHLLFIDAQQKETWILHHHIASVEKLALTTSGCPLVIQCKNFRIVHFIVPRERDCHDIYNSLLQLSKQAKYEDLYAFSYNPKQNDTERRNGWQLIDLAAEYERMGVPNANWQLSDANREYKVCETYPRELYVPRTASRPVIVGSSNFRSKGRLPVLSYCRQGTEAAICRCSQPLSGFSARCLEDEHLLQAISKANPGNRYMYVVDTRPKLNAIANRAAGKGYENEDNYSNIRFQFVGIENIHVMRSSLQKLLEVNGSKGLSVNDFYSGLESSGWLRHIKAVLDAAIFLAKAIVVENASVLVHCSDGWDRTSQVCSLGSLLLDSYYRTMKGFMVLIEKDWISFGHKFSERCGHLDGDPREVSPVFTQFLECVWHLTQQFPQAFEFNEAFLLQIHEHIHSCQFGNFLGNCQKEREELRLKEKTYSLWPFLLDDKKKYLNPLYSSKSQRLTVLEPNTASFNFKFWRNMYHQFDRTLHPRQSVLSIIMNMNEQSKQLEEDIKDLEAKIKQCKNGILTKELLHAVHPESPALKTSLCLKEPSLLPVKDTLRAIEGSSPADNRYCDYAEEFSKSEPTVVSLEYGVARMTC", "length": 617 }, "evidence": [ { "id": "SGD:S000003871", "url": "https://alliancegenome.org/gene/SGD:S000003871#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q91XS1-1", "protein_name": "Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR4", "gene_name": "Mtmr4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGEEGPPSLEYIQAKDLFPPKELVKEEENLQVPFTVLQGEGVEFLGRATDALIAISNYRLHIKFKDSVINVPLRMIDSVESRDMFQLHIACKDSKVVRCHFSTFKQCQEWLSRLSRATARPAKPEDLFAFAYHAWCLGLTEEDQHTHLCQPGEHIRCRQEAELARMGFDLQNVWRVSHINSNYKLCPSYPQKLLVPVWITDKELENVASFRSWKRIPVVVYRHLRNGAAIARCSQPEISWWGWRNADDEYLVTSIAKACALDPGTRASGGSLSTGTNDASEACDTDFDSSLTACSGVESTAAPQKLLILDARSYTAAVANRAKGGGCECEEYYPNCEVLFMGMANIHAIRNSFQYLRAVCSQMPDPSNWLSALESTKWLQHLSVMLKAAVLVANTVDREGRPVLVHCSDGWDRTPQIVALAKILLDPYYRTLEGFQVLVESDWLDFGHKFGDRCGHQENAEDQNEQCPVFLQWLDSVHQLLKQFPCLFEFNEAFLVKLVQHTYSCLYGTFLANNPCEREKRNIYKRTCSVWALLRAGNKNFHNFLYTPGSDVVLHPVCHVRALHLWTAVYLPASSPCTLGEENMDLYLSPVAQSQEFSGRSLDRLPKTRSMDDLLSACDTSSPLTRTSSDPNLNNHSQEVRGSLEPWHSSPEGAETVIDSGVGSPQLTVGEMGLPPPLPSSQKEYLSNKPFKGHKSCSLSYKLLNTSVSWEMKSNTSDIKVLEETEALAPDPSAQEEQGRTSDGLGKPPEQFLEKEAVSSLCSVSSKCGGACDFPEPPQDPLTGTPQQPHLDSMQISPSRCTPDHSQGSLCNPPSVASQTPEPNTDLLSQDPPGSTASISHQEQPSSVPDLIYKKEDAGKRGSKNGQLLENPRFGKMPLELARKPISQSQISEFSFLGSNWDSFQGMMTSFPSGETTPRRLLAYGCCSKRPSNKHIRAAGPCLGGQWAQREGMKSPVCSSHSNGHCTGPGGKNNRMWFSSHPKQVSSTKPSLLSCPSPVPPLYLDDDGLPFPTDVIQHRLRQIEAGYRQEVEQLRRQVRELQMRLDIRHCCAPPAEPPMDYEDDFTCLKESDGSDTEDFGSDHSEDCLSEASWEPVDKKETEVTRWVPDHMASHCFNCDCEFWLAKRRHHCRNCGNVFCAGCCHLKLPIPDQQLYDPVLVCNSCYEHIQVSRARELMSQHLKKPIATASS", "length": 1190 }, "evidence": [ { "id": "SGD:S000003871", "url": "https://alliancegenome.org/gene/SGD:S000003871#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96EF0-1", "protein_name": "Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR8", "gene_name": "MTMR8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDHITVPKVENVKLVDRYVSKKPANGILYLTATHLIYVEASGAARKETWIALHHIATVEKLPITSLGCPLTLRCKNFRVAHFVLDSDLVCHEVYISLLKLSQPALPEDLYAFSYNPKSSKEMRESGWKLIDPISDFGRMGIPNRNWTITDANRNYEICSTYPPEIVVPKSVTLGTVVGSSKFRSKERVPVLSYLYKENNAAICRCSQPLSGFYTRCVDDELLLEAISQTNPGSQFMYVVDTRPKLNAMANRAAGKGYENEDNYANIRFRFMGIENIHVMRSSLQKLLEVCELKTPTMSEFLSGLESSGWLRHIKAIMDAGIFITKAVKVEKASVLVHCSDGWDRTAQVCSVASILLDPFYRTFKGLMILIEKEWISMGHKFSQRCGHLDGDSKEVSPIFTQFLDCIWQLMEQFPCAFEFNENFLLEIHDHVFSCQFGNFLGNCQKDREDLRVYEKTHSVWPFLVQRKPDFRNPLYKGFTMYGVLNPSTVPYNIQFWCGMYNRFDKGLQPKQSMLESLLEIKKQRAMLETDVHELEKKLKVRDEPPEEICTCSQLGNILSQHLGSPLTNPLGFMGINGDLNTLMENGTLSREGGLRAQMDQVKSQGADLHHNCCEIVGSLRAINISGDVGISEAMGISGDMCTFEATGFSKDLGICGAMDISEATGISGNLGISEARGFSGDMGILGDTGISKASTKEADYSKHQ", "length": 704 }, "evidence": [ { "id": "SGD:S000003871", "url": "https://alliancegenome.org/gene/SGD:S000003871#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q96QG7-1", "protein_name": "Myotubularin-related protein 9", "gene_name": "MTMR9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEFAELIKTPRVDNVVLHRPFYPAVEGTLCLTGHHLILSSRQDNTEELWLLHSNIDAIDKRFVGSLGTIIIKCKDFRIIQLDIPGMEECLNIASSIEALSTLDSITLMYPFFYRPMFEVIEDGWHSFLPEQEFELYSSATSEWRLSYVNKEFAVCPSYPPIVTVPKSIDDEALRKVATFRHGGRFPVLSYYHKKNGMVIMRSGQPLTGTNGRRCKEDEKLINATLRAGKRGYIIDTRSLNVAQQTRAKGGGFEQEAHYPQWRRIHKSIERYHILQESLIKLVEACNDQTHNMDRWLSKLEASNWLTHIKEILTTACLAAQCIDREGASILIHGTEGTDSTLQVTSLAQIILEPRSRTIRGFEALIEREWLQAGHPFQQRCAQSAYCNTKQKWEAPVFLLFLDCVWQILRQFPCSFEFNENFLIMLFEHAYASQFGTFLGNNESERCKLKLQQKTMSLWSWVNQPSELSKFTNPLFEANNLVIWPSVAPQSLPLWEGIFLRWNRSSKYLDEAYEEMVNIIEYNKELQAKVNILRRQLAELETEDGMQESP", "length": 549 }, "evidence": [ { "id": "SGD:S000003871", "url": "https://alliancegenome.org/gene/SGD:S000003871#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9NYA4-1", "protein_name": "Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR4", "gene_name": "MTMR4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGEEGPPSLEYIQAKDLFPPKELVKEEENLQVPFTVLQGEGVEFLGRAADALIAISNYRLHIKFKDSVINVPLRMIDSVESRDMFQLHISCKDSKVVRCHFSTFKQCQEWLSRLSRATARPAKPEDLFAFAYHAWCLGLTEEDQHTHLCQPGEHIRCRQEAELARMGFDLQNVWRVSHINSNYKLCPSYPQKLLVPVWITDKELENVASFRSWKRIPVVVYRHLRNGAAIARCSQPEISWWGWRNADDEYLVTSIAKACALDPGTRATGGSLSTGNNDTSEACDADFDSSLTACSGVESTAAPQKLLILDARSYTAAVANRAKGGGCECEEYYPNCEVVFMGMANIHAIRNSFQYLRAVCSQMPDPSNWLSALESTKWLQHLSVMLKAAVLVANTVDREGRPVLVHCSDGWDRTPQIVALAKILLDPYYRTLEGFQVLVESDWLDFGHKFGDRCGHQENVEDQNEQCPVFLQWLDSVHQLLKQFPCLFEFNEAFLVKLVQHTYSCLYGTFLANNPCEREKRNIYKRTCSVWALLRAGNKNFHNFLYTPSSDMVLHPVCHVRALHLWTAVYLPASSPCTLGEENMDLYLSPVAQSQEFSGRSLDRLPKTRSMDDLLSACDTSSPLTRTSSDPNLNNHCQEVRVGLEPWHSNPEGSETSFVDSGVGGPQQTVGEVGLPPPLPSSQKDYLSNKPFKSHKSCSPSYKLLNTAVPREMKSNTSDPEIKVLEETKGPAPDPSAQDELGRTLDGIGEPPEHCPETEAVSALSKVISNKCDGVCNFPESSQNSPTGTPQQAQPDSMLGVPSKCVLDHSLSTVCNPPSAACQTPLDPSTDFLNQDPSGSVASISHQEQLSSVPDLTHGEEDIGKRGNNRNGQLLENPRFGKMPLELVRKPISQSQISEFSFLGSNWDSFQGMVTSFPSGEATPRRLLSYGCCSKRPNSKQMRATGPCFGGQWAQREGVKSPVCSSHSNGHCTGPGGKNQMWLSSHPKQVSSTKPVPLNCPSPVPPLYLDDDGLPFPTDVIQHRLRQIEAGYKQEVEQLRRQVRELQMRLDIRHCCAPPAEPPMDYEDDFTCLKESDGSDTEDFGSDHSEDCLSEASWEPVDKKETEVTRWVPDHMASHCYNCDCEFWLAKRRHHCRNCGNVFCAGCCHLKLPIPDQQLYDPVLVCNSCYEHIQVSRARELMSQQLKKPIATASS", "length": 1195 }, "evidence": [ { "id": "SGD:S000003871", "url": "https://alliancegenome.org/gene/SGD:S000003871#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Y216-1", "protein_name": "Phosphatidylinositol-3-phosphate phosphatase MTMR7", "gene_name": "MTMR7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEHIRTPKVENVRLVDRVSPKKAALGTLYLTATHVIFVENSPDPRKETWILHSQISTIEKQATTATGCPLLIRCKNFQIIQLIIPQERDCHDVYISLIRLARPVKYEELYCFSFNPMLDKEEREQGWVLIDLSEEYTRMGLPNHYWQLSDVNRDYRVCDSYPTELYVPKSATAHIIVGSSKFRSRRRFPVLSYYYKDNHASICRSSQPLSGFSARCLEDEQMLQAIRKANPGSDFVYVVDTRPKLNAMANRAAGKGYENEDNYSNIKFQFIGIENIHVMRNSLQKMLEVCELKSPSMSDFLWGLENSGWLRHIKAIMDAGIFIAKAVSEEGASVLVHCSDGWDRTAQVCSVASLLLDPHYRTLKGFMVLIEKDWISFGHKFNHRYGNLDGDPKEISPVIDQFIECVWQLMEQFPCAFEFNERFLIHIQHHIYSCQFGNFLCNSQKERRELKIQERTYSLWAHLWKNRADYLNPLFRADHSQTQGTLHLPTTPCNFMYKFWSGMYNRFEKGMQPRQSVTDYLMAVKEETQQLEEELEALEERLEKIQKVQLNCTKVKSKQSEPSKHSGFSTSDNSIANTPQDYSGNMKSFPSRSPSQGDEDSALILTQDNLKSSDPDLSANSDQESGVEDLSCRSPSGGEHAPSEDSGKDRDSDEAVFLTA", "length": 660 }, "evidence": [ { "id": "SGD:S000003871", "url": "https://alliancegenome.org/gene/SGD:S000003871#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Y217-1", "protein_name": "Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR6", "gene_name": "MTMR6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEHIRTTKVEQVKLLDRFSTSNKSLTGTLYLTATHLLFIDSHQKETWILHHHIASVEKLALTTSGCPLVIQCKNFRTVHFIVPRERDCHDIYNSLLQLSKQAKYEDLYAFSYNPKQNDSERLQGWQLIDLAEEYKRMGVPNSHWQLSDANRDYKICETYPRELYVPRIASKPIIVGSSKFRSKGRFPVLSYYHQDKEAAICRCSQPLSGFSARCLEDEHLLQAISKANPVNRYMYVMDTRPKLNAMANRAAGKGYENEDNYSNIRFQFVGIENIHVMRSSLQKLLEVNGTKGLSVNDFYSGLESSGWLRHIKAVMDAAIFLAKAITVENASVLVHCSDGWDRTSQVCSLGSLLLDSYYRTIKGFMVLIEKDWISFGHKFSERCGQLDGDPKEVSPVFTQFLECVWHLTEQFPQAFEFSEAFLLQIHEHIHSCQFGNFLGNCQKEREELKLKEKTYSLWPFLLEDQKKYLNPLYSSESHRFTVLEPNTVSFNFKFWRNMYHQFDRTLHPRQSVFNIIMNMNEQNKQLEKDIKDLESKIKQRKNKQTDGILTKELLHSVHPESPNLKTSLCFKEQTLLPVNDALRTIEGSSPADNRYSEYAEEFSKSEPAVVSLEYGVARMTC", "length": 621 }, "evidence": [ { "id": "SGD:S000003871", "url": "https://alliancegenome.org/gene/SGD:S000003871#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z2C4-1", "protein_name": "Phosphatidylinositol-3-phosphate phosphatase MTMR1", "gene_name": "Mtmr1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDRPVAAAAAASAASCEGAGGPGPGPGASWRPSRVAGGASASSRHPSIETLDSPTGSHVEWCKQLIAATISSQISGSVTSENVSRDYKALRDGNKLAQMEEAPLFPGESIKAIVKDVIYICPFMGAVSGTLTVTDFKMYFKNVERDPHFVLDVPLGVISRVEKIGAQSHGDNSCGIEIVCKDMRNLRLAYKQEEQRKLGIFENLNKHAFPLSNGQVLFAFNYKEKFPVNGWKVYDPVSEYKRQGLPNESWKISKINSNYEFCDTYPAIIVVPTSVKDDDLSKVAAFRAKGRVPVLSWIHPESQATITRCSQPLVGPNDKRCKEDEKYLQTIMDANAQSHKLTIFDARQNSVADTNKAKGGGYENESAYPNAELIFLEIHNIHVMRESLRKLKEIVYPSIDESHWLSNVDGTHWLEYIRVLLAGAVRIADKIESGKTSVVIHCSDGWDRTSQLTSLAMLMLDSYYRTIKGFEALIEKEWISFGHRFALRVGHGDDNHADADRSPIFLQFIDCVWQMTRQFPSAFEFNELFLITILDHLYSCLFGTFLCNCEQQRIKEDVYTNTISLWSYINSQLDEFSNPFFVNYENHVLYPVASMSHLELWVNYYVRWNPRMRPQMPIHQNLKELLAIKAELQKRVEDLQREMATRTISSSSERGSSPTHSATPVHTSV", "length": 669 }, "evidence": [ { "id": "MGI:1858271", "url": "https://alliancegenome.org/gene/MGI:1858271#orthology", "database": "AGR" }, { "id": "HGNC:7449", "url": "https://alliancegenome.org/gene/HGNC:7449#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050522-518", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-518#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050327-48", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050327-48#orthology", "database": "AGR" }, { "id": "FB:FBgn0025742", "url": "https://alliancegenome.org/gene/FB:FBgn0025742#orthology", "database": "AGR" }, { "id": "RGD:1306569", "url": "https://alliancegenome.org/gene/RGD:1306569#orthology", "database": "AGR" }, { "id": "SGD:S000003871", "url": "https://alliancegenome.org/gene/SGD:S000003871#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Z2C5-1", "protein_name": "Myotubularin", "gene_name": "Mtm1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASASASKYNSHSLENESIKKVSQDGVSQDVSETVPRLPGELLITEKEVIYICPFNGPIKGRVYITNYRLYLRSLETDSALILDVPLGVISRIEKMGGATSRGENSYGLDITCKDLRNLRFALKQEGHSRRDMFEILVKHAFPLAHNLPLFAFVNEEKFNVDGWTVYNPVEEYRRQGLPNHHWRISFINKCYELCETYPALLVVPYRTSDDDLRRIATFRSRNRLPVLSWIHPENKMVIMRCSQPLVGMSGKRNKDDEKYLDVIRETNKQTSKLMIYDARPSVNAVANKATGGGYESDDAYQNSELSFLDIHNIHVMRESLKKVKDIVYPNIEESHWLSSLESTHWLEHIKLVLTGAIQVADQVSSGKSSVLVHCSDGWDRTAQLTSLAMLMLDSFYRTIEGFEILVQKEWISFGHKFASRIGHGDKNHADADRSPIFLQFIDCVWQMSKQFPTAFEFNEGFLITVLDHLYSCRFGTFLFNCDSARERQKLTERTVSLWSLINSNKDKFKNPFYTKEINRVLYPVASMRHLELWVNYYIRWNPRVKQQQPNPVEQRYMELLALRDDYIKRLEELQLANSAKLADAPASTSSSSQMVPHVQTHF", "length": 603 }, "evidence": [ { "id": "MGI:1099452", "url": "https://alliancegenome.org/gene/MGI:1099452#orthology", "database": "AGR" }, { "id": "HGNC:7448", "url": "https://alliancegenome.org/gene/HGNC:7448#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-051113-128", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-051113-128#orthology", "database": "AGR" }, { "id": "FB:FBgn0025742", "url": "https://alliancegenome.org/gene/FB:FBgn0025742#orthology", "database": "AGR" }, { "id": "RGD:1304582", "url": "https://alliancegenome.org/gene/RGD:1304582#orthology", "database": "AGR" }, { "id": "SGD:S000003871", "url": "https://alliancegenome.org/gene/SGD:S000003871#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Z2C9-1", "protein_name": "Phosphatidylinositol-3-phosphate phosphatase MTMR7", "gene_name": "Mtmr7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEHIRTPKVENVRLVDRVSCKKAALGTLYLTATHVIFVENAPDTRKETWILHSQISTIEKQATTATGCPLLIRCKNFQIVQLVIPQERDCHDVYISLIRLARPVKYEELYCFSFNPKLDKEEREQGWLLVDLSEEYKRMGLPDNYWQLSDVNRDYRVCDSYPTELYVPRSATAHIIVGSSKFRSRRRFPALSYYCKDSHASICRSSQPLSGFSARCLEDEQMLQAIRKANPGSDFIYVVDTRPKLNAMANRAAGKGYENEDNYSNIKFQFIGIENIHVMRNSLQKMLEVCELKSPSMSDFLWGLENSGWLRHIKAIMDAGIFIAKAVSEEGASVLVHCSDGWDRTAQVCSVASLLLDPYYRTLKGFMVLIEKDWISFGHKFNHRYGNLDGDPKEISPVIDQFIECVWQLTEQFPCAFEFNERFLTHIQHHVYSCQFGNFLCNSQKERRELKIQERTYSLWSNLWKNRADYLNPLFRADHSQTQGSLHLPTAPCNFTYKFWNGMYNRFEKGLQPRQSVTDYLMAVKEESQQLEEELESLEERLEKIQKVHLHGTKVKSKQSEPSKHSGFSTSDHSTANTPQDYSGNSKSFPSRSPSQGDEDSALILTQDNLKSSDPDLSVNSDQESGVEDLSCRSPSGGEHAPSEDSGKDRDSDEAVFLTA", "length": 660 }, "evidence": [ { "id": "SGD:S000003871", "url": "https://alliancegenome.org/gene/SGD:S000003871#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Z2D0-1", "protein_name": "Myotubularin-related protein 9", "gene_name": "Mtmr9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEFAELIKTPRVDNVVLHRPFYTAVEGTLCLTGHHLILSSRQDNTEELWLLHSNIDAIDKRFVGSLGTIIIKCKDFRIIQLDIPGMEECLNIASSIEALSTLDSVTLMYPFFYRPMFEVIEDGWHSFLPEQEFEFYSSATSEWRLSYINKDFSICPSYPPTVIVPKSVDDEALRKVAAFRHGGRFPVLSYYHKKNGMVIMRSGQPLTGTNGRRCKEDEKLINATLRAGKRGYLIDTRSLNVAQQARAKGGGFEQEAHYPQWRRIHKSIERYHVLQESLIKLVEACNEQTHNMDRWLGKLEASNWLTHIKEILTTACLAAQCIDREGASVLIHGTEGTDSTLQVTSLAQIILEPRSRTIRGFEALIEREWLQAGHPFQQRCAQSAYCSSKQKWEAPVFLLFLDCVWQILRQFPCSFEFNEHFLIMLFEHAYASQFGTFLGNNESERCKLKLQQKTMSLWSWVNRPGELSKFTNPLFEANNLVIWPSVAPQSLQLWEGIFLRWSRSSKYLDEAYEEMVNIIEYNKELQAKVNVLRRQLAELETEDGL", "length": 545 }, "evidence": [ { "id": "SGD:S000003871", "url": "https://alliancegenome.org/gene/SGD:S000003871#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Z2D1-1", "protein_name": "Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR2", "gene_name": "Mtmr2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKSSSCESLGAQLPAARLPSEDSLSSASTSHSENSVHTKSASAISSDSISTSADNFSPDLRVLREANKLAEMEEPALLPGENIKDMAKDVTYICPFTGAVRGTLTVTSYRLYFKSMERDPPFVLDASLGVISRVEKIGGASSRGENSYGLETVCKDIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNGLPLFAFEYKEVFPENGWKLYDPLLEYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVLSWIHPESQATVTRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYPTIEETHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKENLPKKTVSLWSYINSQLEDFTNPLYGSYSNHVLYPVASMRHLELWVGYYIRWNPRMKPQEPIHSRYKELLAKRAELQRKVEELQREISNRSTSSSERASSPAQCVTPVQTVV", "length": 643 }, "evidence": [ { "id": "MGI:1924366", "url": "https://alliancegenome.org/gene/MGI:1924366#orthology", "database": "AGR" }, { "id": "HGNC:7450", "url": "https://alliancegenome.org/gene/HGNC:7450#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-990715-14", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-990715-14#orthology", "database": "AGR" }, { "id": "FB:FBgn0025742", "url": "https://alliancegenome.org/gene/FB:FBgn0025742#orthology", "database": "AGR" }, { "id": "RGD:1311865", "url": "https://alliancegenome.org/gene/RGD:1311865#orthology", "database": "AGR" }, { "id": "SGD:S000003871", "url": "https://alliancegenome.org/gene/SGD:S000003871#orthology", "database": "AGR" }, { "id": "Q9VMI9", "url": "https://omabrowser.org/oma/group/Q9VMI9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "Q9VMI9", "url": "https://www.uniprot.org/uniprotkb/Q9VMI9" } ], "pmid": "" }, { "name": "chromosome segregation", "id": "GO:0007059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007059", "evidence": [ { "database": "UniProtKB", "id": "Q9VMI9", "url": "https://www.uniprot.org/uniprotkb/Q9VMI9" } ], "pmid": "" }, { "name": "response to wounding", "id": "GO:0009611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009611", "evidence": [ { "database": "UniProtKB", "id": "Q9VMI9", "url": "https://www.uniprot.org/uniprotkb/Q9VMI9" } ], "pmid": "" }, { "name": "cortical actin cytoskeleton organization", "id": "GO:0030866", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030866", "evidence": [ { "database": "UniProtKB", "id": "Q9VMI9", "url": "https://www.uniprot.org/uniprotkb/Q9VMI9" } ], "pmid": "" }, { "name": "endocytic recycling", "id": "GO:0032456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032456", "evidence": [ { "database": "UniProtKB", "id": "Q9VMI9", "url": "https://www.uniprot.org/uniprotkb/Q9VMI9" } ], "pmid": "" }, { "name": "phosphatidylinositol dephosphorylation", "id": "GO:0046856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046856", "evidence": [ { "database": "UniProtKB", "id": "Q9VMI9", "url": "https://www.uniprot.org/uniprotkb/Q9VMI9" } ], "pmid": "" }, { "name": "regulation of endocytic recycling", "id": "GO:2001135", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001135", "evidence": [ { "database": "UniProtKB", "id": "Q9VMI9", "url": "https://www.uniprot.org/uniprotkb/Q9VMI9" } ], "pmid": "" }, { "name": "cell projection assembly", "id": "GO:0030031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030031", "evidence": [ { "database": "UniProtKB", "id": "Q9VMI9", "url": "https://www.uniprot.org/uniprotkb/Q9VMI9" } ], "pmid": "" }, { "name": "regulation of actomyosin structure organization", "id": "GO:0110020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110020", "evidence": [ { "database": "UniProtKB", "id": "Q9VMI9", "url": "https://www.uniprot.org/uniprotkb/Q9VMI9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VMI9", "url": "https://www.uniprot.org/uniprotkb/Q9VMI9" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "Q9VMI9", "url": "https://www.uniprot.org/uniprotkb/Q9VMI9" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VMI9", "url": "https://www.uniprot.org/uniprotkb/Q9VMI9" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "Q9VMI9", "url": "https://www.uniprot.org/uniprotkb/Q9VMI9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "phosphoprotein phosphatase activity", "id": "GO:0004721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004721", "evidence": [ { "database": "UniProtKB", "id": "Q9VMI9", "url": "https://www.uniprot.org/uniprotkb/Q9VMI9" } ], "pmid": "" }, { "name": "protein tyrosine/serine/threonine phosphatase activity", "id": "GO:0008138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008138", "evidence": [ { "database": "UniProtKB", "id": "Q9VMI9", "url": "https://www.uniprot.org/uniprotkb/Q9VMI9" } ], "pmid": "" }, { "name": "phosphatidylinositol-3-phosphate phosphatase activity", "id": "GO:0004438", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004438", "evidence": [ { "database": "UniProtKB", "id": "Q9VMI9", "url": "https://www.uniprot.org/uniprotkb/Q9VMI9" } ], "pmid": "" }, { "name": "phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity", "id": "GO:0052629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052629", "evidence": [ { "database": "UniProtKB", "id": "Q9VMI9", "url": "https://www.uniprot.org/uniprotkb/Q9VMI9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 143, "end_pos": 145, "annotation": "n_glycosylation_sequon" }, { "start_pos": 211, "end_pos": 213, "annotation": "n_glycosylation_sequon" }, { "start_pos": 525, "end_pos": 527, "annotation": "n_glycosylation_sequon" }, { "start_pos": 603, "end_pos": 605, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-DME-1675795", "name": "PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, late endosome membrane", "input_participant_list": [ "R-ALL-1806198" ], "output_participant_list": [], "enzyme_list": [ "Q8MLR7-1", "Q9VMI9-1" ], "evidence": [ { "id": "R-DME-1675795", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1675795" } ] }, { "id": "R-DME-1675994", "name": "PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A1ZAS8-1", "Q8MLR7-1", "Q9VMI9-1" ], "evidence": [ { "id": "R-DME-1675994", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1675994" } ] }, { "id": "R-DME-1676065", "name": "PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, late endosome membrane", "input_participant_list": [ "R-ALL-1806289" ], "output_participant_list": [ "R-ALL-1806212" ], "enzyme_list": [ "Q8MLR7-1", "Q9VMI9-1" ], "evidence": [ { "id": "R-DME-1676065", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1676065" } ] }, { "id": "R-DME-1676105", "name": "PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, early endosome membrane", "input_participant_list": [ "R-ALL-1806205" ], "output_participant_list": [ "R-ALL-1806259" ], "enzyme_list": [ "Q9VMI9-1" ], "evidence": [ { "id": "R-DME-1676105", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1676105" } ] }, { "id": "R-DME-1676141", "name": "PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, early endosome membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VMI9-1" ], "evidence": [ { "id": "R-DME-1676141", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1676141" } ] }, { "id": "R-DME-1676203", "name": "PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [ "R-ALL-1806240" ], "enzyme_list": [ "A1ZAS8-1", "Q8MLR7-1", "Q9VMI9-1" ], "evidence": [ { "id": "R-DME-1676203", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1676203" } ] }, { "id": "R-DME-6809680", "name": "MTMR12 binds MTM1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VMI9-1" ], "evidence": [ { "id": "R-DME-6809680", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6809680" } ] }, { "id": "R-DME-6809707", "name": "MTMR12 binds MTMR2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VMI9-1" ], "evidence": [ { "id": "R-DME-6809707", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6809707" } ] }, { "id": "R-DME-6809720", "name": "PI3P is dephosphorylated to PI by MTM1:MTMR12", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, early endosome membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VMI9-1" ], "evidence": [ { "id": "R-DME-6809720", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6809720" } ] }, { "id": "R-DME-6809764", "name": "SBF1 binds MTMR2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VMI9-1" ], "evidence": [ { "id": "R-DME-6809764", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6809764" } ] }, { "id": "R-DME-6809777", "name": "PI3P is dephosphorylated to PI by MTMR2:SBF1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [ "R-ALL-5676030" ], "output_participant_list": [], "enzyme_list": [ "Q9VMI9-1" ], "evidence": [ { "id": "R-DME-6809777", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6809777" } ] }, { "id": "R-DME-6809778", "name": "PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [ "R-ALL-6809774" ], "output_participant_list": [ "R-ALL-422529" ], "enzyme_list": [ "Q9VMI9-1" ], "evidence": [ { "id": "R-DME-6809778", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6809778" } ] }, { "id": "R-DME-9693125", "name": "RHOF binds effectors at the plasma membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P02572-1", "P10987-1", "P48148-1", "P83967-1", "P02574-1", "P10981-1", "P53501-1", "O76742-1", "Q9VMI9-1" ], "evidence": [ { "id": "R-DME-9693125", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9693125" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-1806198", "participant_name": "PI3P [late endosome membrane]", "crossref": [ { "id": "58088", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-1806205", "participant_name": "PI(3,5)P2 [early endosome membrane]", "crossref": [ { "id": "57923", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-1806212", "participant_name": "PI5P [late endosome membrane]", "crossref": [ { "id": "57795", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-1806240", 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Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VMK8", "url": "https://www.uniprot.org/uniprotkb/Q9VMK8" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VMK8", "url": "https://www.uniprot.org/uniprotkb/Q9VMK8" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMK8", "url": "https://www.uniprot.org/uniprotkb/Q9VMK8" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMK8", "url": "https://www.uniprot.org/uniprotkb/Q9VMK8" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VMK8", "url": "https://www.uniprot.org/uniprotkb/Q9VMK8" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VMK8", "url": "https://www.uniprot.org/uniprotkb/Q9VMK8" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VMK8", "url": "https://www.uniprot.org/uniprotkb/Q9VMK8" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi 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"recommended", "evidence": [ { "id": "Q9VMM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMM9" } ] }, { "name": "CG11147", "type": "synonym", "evidence": [ { "id": "NP_608954", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608954" }, { "id": "Q9VMM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMM9" } ] }, { "name": "DmCG11147", "type": "synonym", "evidence": [ { "id": "NP_608954", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608954" }, { "id": "Q9VMM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMM9" } ] }, { "name": "Dmel\\CG11147", "type": "synonym", "evidence": [ { "id": "NP_608954", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608954" } ] }, { "name": "Dmel_CG11147", "type": "synonym", "evidence": [ { "id": "Q9VMM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMM9" } ] } ], "protein_names": [ { "name": "CG11147-PA", "type": "synonym", "evidence": [ { "id": "NP_608954", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608954" } ] }, { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "Q9VMM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMM9/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein, isoform A", "type": "synonym", "evidence": [ { "id": "NP_608954", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608954" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VMM9", "url": "https://www.uniprot.org/uniprotkb/Q9VMM9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG11147", "url": "https://www.uniprot.org/uniprotkb/Q9VMM9", "locus": { "chromosome": "2L", "start_pos": 5733675, "end_pos": 5741244, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0031734", "url": "https://www.ensemblgenomes.org/id/FBgn0031734" } ] } } ], "crossref": [ { "id": "FB:FBgn0031734", "url": "https://alliancegenome.org/gene/FB:FBgn0031734", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0031734", "url": "https://bgee.org/?page=gene&gene_id=FBgn0031734", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0031734", "url": "https://flybase.org/reports/FBgn0031734", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "33803", "url": "https://www.ncbi.nlm.nih.gov/gene/33803", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013525", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013525", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047817", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047817", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG11147", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG11147", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FRYNQAF", "url": "https://omabrowser.org/oma/group/FRYNQAF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VMM9", "url": "https://www.orthodb.org/?gene=Q9VMM9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43038", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43038", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43038:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43038:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00005", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00005", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12698", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12698", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_608954", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608954", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VMM9", "url": "https://www.uniprot.org/uniprotkb/Q9VMM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VMM9-1", "url": "https://www.uniprot.org/uniprotkb/Q9VMM9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAVEVRNGYKYYGSKSNPKIVLNQLNMNVMRGSIYGLLGASGCGKTTLLSCIVGQRRLNGGEVVVLGAKPGEPGSGVPGSRVGFMPQEIALVEEMTVKETIFYFGRIYGLTDERIREKFKLLKELLQLPPARQMIKQCSGGQQRRLSFACAMIHDPELLILDEPTVGLDPMLREKIWDFLVETTRNSKLAVIITTHYIEEAKQANCIGLMRNGVLLAEDTPTNIMIKFGTQSIEDAFLILSQRQGNEDELAQIMDHNKNQALPAAVLPPEVIDTHEPNMPEKQPIPFEEPLNENRKKIFFTTKGRVKALMTKNFVQLFRQPSGIIFMLLFPIIQLTCFYLAIGKTPTNLEIGVYSGEVENYGECFDENLVTVYKDSDNESCLFNKLSCRYIRVLGDDVATRKYYASEADALNDAKRATTVGYLHFAQNFSDSILSVMEDGIHSSDGAVDHAELSIHIDMTDQQVAYFMQRKLRDKFSTFMRSVVKDCNVSTAIVDLPVQFQEPIFGSTDIEFQQYCAPGVVMTMVFFLATLMTAAVFISERMDGIWDRTLLAGVSATEMLWAHLLTQLIIMALQSFEVIMYIGLVFDTYNNGDTTTLIGLLTLTAFCGMLFGLFISVFCKSHTEANFVATGAFYPMIILCGLLWPLESMPQFLQDLVMVLPFTIPSISARNVIEKGWSITHEKVYNGFLVMAGWTIIFFVLCLIGIRRKA", "length": 711, "header": "tr|Q9VMM9-1|Q9VMM9_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG11147 PE=4 SV=2 CANONICAL=Q9VMM9-1" }, "isoforms": [ { "isoform_ac": "Q9VMM9-1", "url": "https://www.uniprot.org/uniprotkb/Q9VMM9/entry#Q9VMM9-1", "sequence": { "sequence": "MAAVEVRNGYKYYGSKSNPKIVLNQLNMNVMRGSIYGLLGASGCGKTTLLSCIVGQRRLNGGEVVVLGAKPGEPGSGVPGSRVGFMPQEIALVEEMTVKETIFYFGRIYGLTDERIREKFKLLKELLQLPPARQMIKQCSGGQQRRLSFACAMIHDPELLILDEPTVGLDPMLREKIWDFLVETTRNSKLAVIITTHYIEEAKQANCIGLMRNGVLLAEDTPTNIMIKFGTQSIEDAFLILSQRQGNEDELAQIMDHNKNQALPAAVLPPEVIDTHEPNMPEKQPIPFEEPLNENRKKIFFTTKGRVKALMTKNFVQLFRQPSGIIFMLLFPIIQLTCFYLAIGKTPTNLEIGVYSGEVENYGECFDENLVTVYKDSDNESCLFNKLSCRYIRVLGDDVATRKYYASEADALNDAKRATTVGYLHFAQNFSDSILSVMEDGIHSSDGAVDHAELSIHIDMTDQQVAYFMQRKLRDKFSTFMRSVVKDCNVSTAIVDLPVQFQEPIFGSTDIEFQQYCAPGVVMTMVFFLATLMTAAVFISERMDGIWDRTLLAGVSATEMLWAHLLTQLIIMALQSFEVIMYIGLVFDTYNNGDTTTLIGLLTLTAFCGMLFGLFISVFCKSHTEANFVATGAFYPMIILCGLLWPLESMPQFLQDLVMVLPFTIPSISARNVIEKGWSITHEKVYNGFLVMAGWTIIFFVLCLIGIRRKA", "length": 711, "header": "tr|Q9VMM9-1|Q9VMM9_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG11147 PE=4 SV=2 CANONICAL=Q9VMM9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VMM9", "url": "https://www.uniprot.org/uniprotkb/Q9VMM9" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VMM9", "url": "https://www.uniprot.org/uniprotkb/Q9VMM9" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMM9", "url": "https://www.uniprot.org/uniprotkb/Q9VMM9" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMM9", "url": "https://www.uniprot.org/uniprotkb/Q9VMM9" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VMM9", "url": "https://www.uniprot.org/uniprotkb/Q9VMM9" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VMM9", "url": "https://www.uniprot.org/uniprotkb/Q9VMM9" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VMM9", "url": "https://www.uniprot.org/uniprotkb/Q9VMM9" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMM9", "url": "https://www.uniprot.org/uniprotkb/Q9VMM9" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMM9", "url": "https://www.uniprot.org/uniprotkb/Q9VMM9" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VMM9", "url": "https://www.uniprot.org/uniprotkb/Q9VMM9" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VMM9", "url": "https://www.uniprot.org/uniprotkb/Q9VMM9" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG11147", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG11147", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8N7T5J6-1", "protein_name": "ABC transporter G family member 23 isoform X1", "gene_name": "abch1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSGSGTHEALSGSTEMEQRSLESGTMKTDLEAGSFSAAIHCHDVCRSYGKLKVLNNLNLTLPQGQIYGLLGPSGCGKTTLLKCIVGTLKISRGHITVLGKPPAFPGHEVPGKMVGYMPQDIALYNEFTISNTLWFFGRIHGLSSKETEARMSFLIDFLDLPQKHSLVKNLSGGQRRRVSLGAALLQNPKLLILDEPTVGVDPVLRAKIWQHLVEIVRGGQVSIIITTHYIEEARQANTVGLMRNGRLLAEGPPDAVMKQHNAATLETAFLQLCEDSDQSGPKQSPQGRLLDSSPSPDSMRDEIREPILRKSTSEEMPKCKADWKVRARHIIPKWSNIAALMIKTMVRMRRLPGSLCFQFLLPVIQICLMCLCIGGDPKNIDVAVVNNESSPSAFSRSLLSFLDNTSINQVSLSHSDAFDGIRNGEYWGVIEFGENFTSYLTKRMLQPRVSREVVEGGSVHAWLDLTNRQIALMLQKKLHQAFEAFMEKRLGSMSYMVAVPIKFEEPIYGSKNTDFTTFVTPGAVLSITFYLAVGLTALSFVLERKEGLLDRCWVAGVSSLETMLAHLFSQLFVISVQIILLLIFTLLVFNIPNEGSLALVISLIVLQGVTGISFGLVISSAIDDEQSANQAALGVFYPNLILSGVIWPVECIPYPLRYLSLVLPQTYASEALRCIMYRGWGLSRMMVWRGFAVTLGWNTFFLMLATIILKLRT", "length": 713 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050517-42", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050517-42#orthology", "database": "AGR" }, { "id": "FB:FBgn0031734", "url": "https://alliancegenome.org/gene/FB:FBgn0031734#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q55EH8-1", "protein_name": "ABC transporter G family member 23", "gene_name": "abcG23", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGDNIVINLNNVSRSYGNVKVIEKLNFTINKGTINSLIGSSGSGKTTILKTILGKLKQDDGIVQVFGKEPCGKGSEIPGSSVGYAPQDVCLYNEITIEETLSFFASIHRMPKDEYIKKRDSLVEILELPSLSKIISELSGGQQRRVSLATALIHSPKLLILDEPTVGVCPLVSSKIWEHLIFLTKNFGVTIIITTHYLQECRSCDNIFLLRNGRILESGPPNYLLSKYECSLLEDVYYKLCRGDEEISLQLIDSKNNEKINRDINTSIPLEFISNGANINNDDILISNTNKPIIKKDAKIYKERLSDFKNKLQIWFSHSITISIRKLTQMYRLKFPLVFEIISPSLLITLFFLAIGNVPHDLKFGIKNIDSGSLSGDFINALSDGNNIFNFIQINDTSNAIQMIESSDLWGLIDIPVNFTNGMINKLFNPLEKSFENSEMEIYMDLSNFQMNLMVDVQFQKAFNKIANDSGIKLLPTNFHAVYGDQNANFNWFLAPAMICIITYVHCMNFLSITFVREKNDGTRDRILLYGVSPVSNVLGHILAHIPILLVQFSIQLLIAVFAFGVPIKGNIVLIYLFFILINTVGMCQGILISLISKAEVDAVQLCLAIFICSLCMAGIIWPTEAIITFGWISNLVPTKWSGLALRGIMIKDLPFSHQHIWKSLIIIISYIIGTFSLIVISTPIGDRNFNFKKLFKRIKK", "length": 701 }, "evidence": [ { "id": "Q9VMM9", "url": "https://omabrowser.org/oma/group/Q9VMM9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9VAU1-1", "protein_name": "Snustorr, isoform A", "gene_name": "snu", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAPKKEATLSQQQTQQPIMDLERIKRHFSWSDPSAIISTDSAMAATNNDGGTQPNAVAAWGAPANGPRNTQAAVSVRHAFKAYGKKKNANQVLNNLNMTVPKGTIYGLLGASGCGKTTLLSCIVGRRYMDAGEIFVLGGKPGTRGSGVPGKRVGYMPQEIALYGEFSIQETMMYFGWIFGMDTKEILERLQFLLNFLDLPSEKRLVKNLSGGQQRRVSFAVALMHDPELLILDEPTVGVDPLLRQSIWNHLVHITKAGQKTVIITTHYIEEARQAHTIGLMRSGHLLAEESPSVLLSIYKCISLEEVFLKLSRIQSQKGDVTHVNFSNNISLHAMAFGSKMDKPSSSQEGGVVGLNFHQSKEVLINDSNGSIYTLNQEPYSPPPSRRNNNPNDEESCQDCYSNLCKITSKGKIRALLTKNMLRMWRNVGVMLFIFALPVMQVILFCLAIGRDPQGLNLAIVNGEMNDTVRENCYWEDGCHFKNLGCRYLSHLNTSVVKTYYEDLDDAKEAVRKGTAWGAVYISENFTDAFIARANLGRDSDDETIDSSEVKVWLDMSNQQIGVMLNRDIQLAFRDFAMGLLGQCGSNPKLGDVPIQFRDPIYGTMNPSFTDFVAPGVILTIVFFLAVALTSSALIIERTEGLLDRSWVAGVSPFEILFSHVITQFVVMCGQTTLVLIFMLVVFGVTNNGDLFWVIVLTLLQGMCGMCFGFLISSVCELERNAIQLALGSFYPTLLLSGVIWPIEGMPVVLRYISLCLPLTLATSSLRSILTRGWAILESDVYIGYVSTLSWIVGFLVLTLLVLRAKRG", "length": 808 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050517-42", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050517-42#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VMM9", "url": "https://www.uniprot.org/uniprotkb/Q9VMM9" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "Q9VMM9", "url": "https://www.uniprot.org/uniprotkb/Q9VMM9" } ], "pmid": "" }, { "name": "ABC-type transporter activity", "id": "GO:0140359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140359", "evidence": [ { "database": "UniProtKB", "id": "Q9VMM9", "url": "https://www.uniprot.org/uniprotkb/Q9VMM9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VMM9", "url": "https://www.uniprot.org/uniprotkb/Q9VMM9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 379, "end_pos": 381, "annotation": "n_glycosylation_sequon" }, { "start_pos": 429, "end_pos": 431, "annotation": "n_glycosylation_sequon" }, { "start_pos": 489, "end_pos": 491, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VMM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMM9" }, { "id": "PS51012", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51012" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ABC transmembrane type-2", "eco_id": "ECO_0000259", "start_pos": 478, "end_pos": 710, "start_aa": "Ser", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q9VMM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMM9" }, { "id": "PS50893", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50893" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ABC transporter", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 238, "start_aa": "Val", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 379, "end_pos": 381 }, { "start_pos": 429, "end_pos": 431 }, { "start_pos": 489, "end_pos": 491 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": 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"count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VMN1-1", "uniprot_ac": "Q9VMN1", "uniprot_id": "Q9VMN1_DROME", "mass": { "chemical_mass": 57098.0, "monoisotopic_mass": 57098.0 }, "refseq": { "ac": "NP_608952", "name": "uncharacterized protein, isoform B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608952" }, "gene_names": [ { "name": "Dmel\\CG11149", "type": "recommended", "evidence": [ { "id": "Q9VMN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMN1" } ] }, { "name": "CG11149", "type": "synonym", "evidence": [ { "id": "NP_608952", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608952" }, { "id": "Q9VMN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMN1" } ] }, { "name": "Dmel\\CG11149", "type": "synonym", "evidence": [ { "id": "NP_608952", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608952" } ] }, { "name": "Dmel_CG11149", "type": "synonym", "evidence": [ { "id": "Q9VMN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMN1" } ] }, { "name": "dibeta3GnT4", "type": "synonym", "evidence": [ { "id": "NP_608952", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608952" }, { "id": "Q9VMN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMN1" } ] } ], "protein_names": [ { "name": "CG11149-PB", "type": "synonym", "evidence": [ { "id": "NP_608952", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608952" } ] }, { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "Q9VMN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMN1/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein, isoform B", "type": "synonym", "evidence": [ { "id": "NP_608952", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608952" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VMN1", "url": "https://www.uniprot.org/uniprotkb/Q9VMN1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG11149", "url": "https://www.uniprot.org/uniprotkb/Q9VMN1", "locus": { "chromosome": "2L", "start_pos": 5718121, "end_pos": 5720899, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0031732", "url": "https://www.ensemblgenomes.org/id/FBgn0031732" } ] } } ], "crossref": [ { "id": "FB:FBgn0031732", "url": "https://alliancegenome.org/gene/FB:FBgn0031732", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0031732", "url": "https://bgee.org/?page=gene&gene_id=FBgn0031732", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0031732", "url": "https://flybase.org/reports/FBgn0031732", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "33800", "url": "https://www.ncbi.nlm.nih.gov/gene/33800", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "MYKVQAN", "url": "https://omabrowser.org/oma/group/MYKVQAN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VMN1", "url": "https://www.orthodb.org/?gene=Q9VMN1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47412", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47412", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47412:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47412:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13896", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13896", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_608952", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608952", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VMN1", "url": "https://www.uniprot.org/uniprotkb/Q9VMN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VMN1-1", "url": "https://www.uniprot.org/uniprotkb/Q9VMN1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATISFCNRKYVRLWPVLILFNVALLLVWRNLQQAQKLAASSNTGGQKSVGLLLSNESNPSRFSANFHLANDQHPKIIRREDSARTKELRSLLKCRDRSLRFERLQHGEFWLLQNLVMGRKSREVGCAESVTYTTNGDFTFFDNLEMVVSRWRAPVSFAIHTPGYDLNTTLDAIRYVRNCLPESDSIKDWVSFHVYFPNQHMPEYVPYDEAEVLMYPHMCTLANGSLVSPLYTQIPTTDSYKSRANLTYPINVGRNIARLATNTHFIFACDIELYPSVGFVDQFLDMVARNHSVLALDPRQRRRVYPLPVFEIETGAKVPVDKDELLALYRKQQAQVFHLKLCPTCHTIPGQEEWLNRTSRADDHLHVFSKALRKWKFRAWEPFYVSDNTEPLFDERVTWEGQSNKRIQVSYYCSQVSVSQCNLLLQNYAMCLLDYEYHVLSPAFLVHSPGIKQSSKADSTRLQYAKEMTKFIKNKIEPEYRVLFGKNSACKT", "length": 493, "header": "tr|Q9VMN1-1|Q9VMN1_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG11149 PE=4 SV=1 CANONICAL=Q9VMN1-1" }, "isoforms": [ { "isoform_ac": "Q9VMN1-1", "url": "https://www.uniprot.org/uniprotkb/Q9VMN1/entry#Q9VMN1-1", "sequence": { "sequence": "MATISFCNRKYVRLWPVLILFNVALLLVWRNLQQAQKLAASSNTGGQKSVGLLLSNESNPSRFSANFHLANDQHPKIIRREDSARTKELRSLLKCRDRSLRFERLQHGEFWLLQNLVMGRKSREVGCAESVTYTTNGDFTFFDNLEMVVSRWRAPVSFAIHTPGYDLNTTLDAIRYVRNCLPESDSIKDWVSFHVYFPNQHMPEYVPYDEAEVLMYPHMCTLANGSLVSPLYTQIPTTDSYKSRANLTYPINVGRNIARLATNTHFIFACDIELYPSVGFVDQFLDMVARNHSVLALDPRQRRRVYPLPVFEIETGAKVPVDKDELLALYRKQQAQVFHLKLCPTCHTIPGQEEWLNRTSRADDHLHVFSKALRKWKFRAWEPFYVSDNTEPLFDERVTWEGQSNKRIQVSYYCSQVSVSQCNLLLQNYAMCLLDYEYHVLSPAFLVHSPGIKQSSKADSTRLQYAKEMTKFIKNKIEPEYRVLFGKNSACKT", "length": 493, "header": "tr|Q9VMN1-1|Q9VMN1_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG11149 PE=4 SV=1 CANONICAL=Q9VMN1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycosyltransferase-activity" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VMN1", "url": "https://www.uniprot.org/uniprotkb/Q9VMN1" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VMN1", "url": "https://www.uniprot.org/uniprotkb/Q9VMN1" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMN1", "url": "https://www.uniprot.org/uniprotkb/Q9VMN1" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker 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melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VMP0", "url": "https://www.uniprot.org/uniprotkb/Q9VMP0" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VMP0", "url": "https://www.uniprot.org/uniprotkb/Q9VMP0" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMP0", "url": "https://www.uniprot.org/uniprotkb/Q9VMP0" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMP0", "url": "https://www.uniprot.org/uniprotkb/Q9VMP0" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VMP0", "url": "https://www.uniprot.org/uniprotkb/Q9VMP0" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VMP0", "url": "https://www.uniprot.org/uniprotkb/Q9VMP0" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VMP0", "url": "https://www.uniprot.org/uniprotkb/Q9VMP0" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMP0", "url": "https://www.uniprot.org/uniprotkb/Q9VMP0" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMP0", "url": "https://www.uniprot.org/uniprotkb/Q9VMP0" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VMP0", "url": "https://www.uniprot.org/uniprotkb/Q9VMP0" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VMP0", "url": "https://www.uniprot.org/uniprotkb/Q9VMP0" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG18266", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG18266", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZUR6-1", "protein_name": "Coiled-coil domain containing 34", "gene_name": "Ccdc34", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTTRPSAGADWPEGARAETAGRTRRRPCSGRLNLAGLMQAAGPWRAASPVPCTRYLARCKPGFRPSSSFVVDLIVDSQGPGLEDVALTECLLPPSLSCSNSTLSLLSPLGHRSFPFGEDDSEGEDEEALDEDACESEAKVESLEGMELQGRSSCEVESQDKQEEKQVLLQESSLTPWEMWFVGKEKEERGRLQQKVLEELNRQIEKRKEMEEREKRKIIAEVKHKEWVQKKNKQERKERVQKINKEMEEKAAKKREKEHLQEKAKEKYQEWLKKKKAEECEKKKKEKEKEKQRQAELQEKKEIAEKKFKEWLENAKNKPRPAAKSYGYSSGKLTGFYSGNSYPEPTFYNPIPWKPIPMPPPKEAKSGPGKKSSREAVKKSNRPATSQPLTASSLAVHNARSSLCLGSLCRVQR", "length": 413 }, "evidence": [ { "id": "MGI:1915451", "url": "https://alliancegenome.org/gene/MGI:1915451#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": 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"MAFCGHVTSSGQIVLRDEIFSSRTCIARSPSSGGSLNSMSSPSSLAQNTTRTYFFKDDGGNPSPQSTDNWSLGGLKRSEIQSNLVPSLCLSSQESSLNYLSHCKGIKVDRQPEAAYQNWYSAKQQQLLEKQRRIKEEQEFKQQRTEERKQLARMCYEQWLKDKARQAANLQLESHIQDAAMKASIALRKNPLESLRKNPVVSSLSGLGSLGSGPSSSTAPRRIRKVSKDEIRRVVEDWWLKKQSQQQAQREEKRRAMLSKALKEEQRRQLAQDAWSKWMSNVDAKPKPVPLNQGMDSLRGTISQLYVNPTPWMGPVKQTQM", "length": 321 }, "evidence": [ { "id": "MGI:1915451", "url": "https://alliancegenome.org/gene/MGI:1915451#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VMP2-1", "protein_name": "Coiled-coil domain-containing protein", "gene_name": "Dmel\\CG14011", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAFLGKVNSQGTLIDHELFCMTQPSQQDSDGQAREMGARVLLPRRKGSRTFIKTCDKDSLVRSMGSPSTVRYVGSSESSSEVNSLDETETSTLRCCSDLSLGTLKSTKTIEGPRVGELGEDIELQTESETVCLHLGSPSSSTSTDRSSCSSRSCPSSRSGNNSSDKDSTTSMCSWEEAMSRDDSMLAPLELPLSHSLPSLRLGSSVGSPPLTYTRRIEPLHIRRSAGEAYENWLSGKQRQCQYKLQAQQAEREAQRQRTELRQRLAKEKYEQWCQQKAQQTTSTAKLTKPDRSAQLPPQKNMASVQHHLQEWELHKLRLLEQRRLEQRNAERRRQEEKAARRSQAEEAFSRWMSNVAQRPKPVPSSQGMKSLRGTVSDIFINPKQWVN", "length": 388 }, "evidence": [ { "id": "MGI:1915451", "url": "https://alliancegenome.org/gene/MGI:1915451#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 183, "end_pos": 185, "annotation": "n_glycosylation_sequon" }, { "start_pos": 46, "end_pos": 48, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VMP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMP0" }, { "id": "PF13904", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13904" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Coiled-coil", "eco_id": "ECO_0000259", "start_pos": 303, "end_pos": 473, "start_aa": "Gln", "end_aa": "Trp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 183, "end_pos": 185 }, { "start_pos": 46, "end_pos": 48 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", 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"field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { 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"uniprot_ac": "Q9VMP4", "uniprot_id": "Q9VMP4_DROME", "mass": { "chemical_mass": 104444.0, "monoisotopic_mass": 104444.0 }, "refseq": { "ac": "NP_523484", "name": "glutamate receptor IIA", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523484" }, "gene_names": [ { "name": "GluRIIA", "type": "recommended", "evidence": [ { "id": "Q9VMP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ] }, { "name": "CG6992", "type": "synonym", "evidence": [ { "id": "NP_523484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523484" }, { "id": "Q9VMP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ] }, { "name": "D-GluRIIA", "type": "synonym", "evidence": [ { "id": "NP_523484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523484" }, { "id": "Q9VMP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ] }, { "name": "DGluR-IIA", "type": "synonym", "evidence": [ { "id": "NP_523484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523484" }, { "id": "Q9VMP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ] }, { "name": "DGluR-II", "type": "synonym", "evidence": [ { "id": "NP_523484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523484" }, { "id": "Q9VMP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ] }, { "name": "DGluR2a", "type": "synonym", "evidence": [ { "id": "NP_523484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523484" }, { "id": "Q9VMP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ] }, { "name": "DGluRIIA", "type": "synonym", "evidence": [ { "id": "NP_523484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523484" }, { "id": "Q9VMP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ] }, { "name": "DGluRIIa", "type": "synonym", "evidence": [ { "id": "NP_523484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523484" }, { "id": "Q9VMP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ] }, { "name": "DgluRII", "type": "synonym", "evidence": [ { "id": "NP_523484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523484" }, { "id": "Q9VMP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ] }, { "name": "DmelGluRIIA", "type": "synonym", "evidence": [ { "id": "NP_523484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523484" }, { "id": "Q9VMP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ] }, { "name": "Dmel\\CG6992", "type": "synonym", "evidence": [ { "id": "NP_523484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523484" }, { "id": "Q9VMP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ] }, { "name": "Dmel_CG6992", "type": "synonym", "evidence": [ { "id": "Q9VMP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ] }, { "name": "Glu-RIIA", "type": "synonym", "evidence": [ { "id": "NP_523484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523484" }, { "id": "Q9VMP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ] }, { "name": "Glu-RII", "type": "synonym", "evidence": [ { "id": "NP_523484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523484" }, { "id": "Q9VMP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ] }, { "name": "GluR-IIA", "type": "synonym", "evidence": [ { "id": "NP_523484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523484" }, { "id": "Q9VMP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ] }, { "name": "GluR2a", "type": "synonym", "evidence": [ { "id": "NP_523484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523484" }, { "id": "Q9VMP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ] }, { "name": "GluR2", "type": "synonym", "evidence": [ { "id": "NP_523484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523484" }, { "id": "Q9VMP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ] }, { "name": "GluRII-A", "type": "synonym", "evidence": [ { "id": "NP_523484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523484" }, { "id": "Q9VMP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ] }, { "name": "GluRIIA", "type": "synonym", "evidence": [ { "id": "NP_523484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523484" } ] }, { "name": "GluRIIa", "type": "synonym", "evidence": [ { "id": "NP_523484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523484" }, { "id": "Q9VMP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ] }, { "name": "GluRII", "type": "synonym", "evidence": [ { "id": "NP_523484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523484" }, { "id": "Q9VMP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ] }, { "name": "GluR[[IIa]]", "type": "synonym", "evidence": [ { "id": "NP_523484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523484" }, { "id": "Q9VMP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ] }, { "name": "GluR", "type": "synonym", "evidence": [ { "id": "NP_523484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523484" }, { "id": "Q9VMP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ] }, { "name": "GlurIIA", "type": "synonym", "evidence": [ { "id": "NP_523484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523484" }, { "id": "Q9VMP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ] }, { "name": "dGluRIIA", "type": "synonym", "evidence": [ { "id": "NP_523484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523484" }, { "id": "Q9VMP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ] }, { "name": "dGluRII", "type": "synonym", "evidence": [ { "id": "NP_523484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523484" }, { "id": "Q9VMP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ] }, { "name": "dglur-IIA", "type": "synonym", "evidence": [ { "id": "NP_523484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523484" }, { "id": "Q9VMP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ] }, { "name": "dglurIIA", "type": "synonym", "evidence": [ { "id": "NP_523484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523484" }, { "id": "Q9VMP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ] }, { "name": "gluIIA", "type": "synonym", "evidence": [ { "id": "NP_523484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523484" }, { "id": "Q9VMP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ] }, { "name": "gluRIIA", "type": "synonym", "evidence": [ { "id": "NP_523484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523484" }, { "id": "Q9VMP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ] }, { "name": "glurIIA", "type": "synonym", "evidence": [ { "id": "NP_523484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523484" }, { "id": "Q9VMP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ] }, { "name": "gluriia", "type": "synonym", "evidence": [ { "id": "NP_523484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523484" }, { "id": "Q9VMP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ] } ], "protein_names": [ { "name": "CG6992-PI", "type": "synonym", "evidence": [ { "id": "NP_523484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523484" } ] }, { "name": "GluRIIA-PI", "type": "synonym", "evidence": [ { "id": "NP_523484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523484" } ] }, { "name": "Glutamate receptor IIA", "type": "synonym", "evidence": [ { "id": "Q9VMP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4/entry#names_and_taxonomy" } ] }, { "name": "glutamate IIA receptor", "type": "synonym", "evidence": [ { "id": "NP_523484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523484" } ] }, { "name": "glutamate receptor IIA", "type": "synonym", "evidence": [ { "id": "NP_523484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523484" } ] }, { "name": "glutamate receptor subunit IIA", "type": "synonym", "evidence": [ { "id": "NP_523484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523484" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VMP4", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "GluRIIA", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4", "locus": { "chromosome": "2L", "start_pos": 5558994, "end_pos": 5555072, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0004620", "url": "https://www.ensemblgenomes.org/id/FBgn0004620" } ] } } ], "crossref": [ { "id": "FB:FBgn0004620", "url": "https://alliancegenome.org/gene/FB:FBgn0004620", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0004620", "url": "https://bgee.org/?page=gene&gene_id=FBgn0004620", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06382", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06382", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13714", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13714", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0004620", "url": "https://flybase.org/reports/FBgn0004620", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "33788", "url": "https://www.ncbi.nlm.nih.gov/gene/33788", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VMP4", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VMP4*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR001320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015683", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015683", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019594", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028082", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028082", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG6992", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG6992", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "REWMPPN", "url": "https://omabrowser.org/oma/group/REWMPPN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VMP4", "url": "https://www.orthodb.org/?gene=Q9VMP4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18966", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18966", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00060", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00060", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01094", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01094", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10613", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10613", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-451307", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-451307", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-451308", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-451308", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-500657", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-500657", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_523484", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523484", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VMP4", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VMP4-1", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRLCPVVIYAFIIIIGFLEGIIALGGDDRNEITVGAIFYENEKEIELSFDQAFREVNNMKFSELRFVTIKRYMPTNDSFLLQQITCELISNGVAAIFGPSSKAASDIVAQIANATGIPHIEYDLKLEATRQEQLNHQMSINVAPSLSVLSRAYFEIIKSNYEWRTFTLIYETPEGLARLQDLMNIQALNSDYVKLRNLADYADDYRILWKETDETFHEQRIILDCEPKTLKELLKVSIDFKLQGPFRNWFLTHLDTHNSGLRDIYNEDFKANITSVRLKVVDANPFERKKTRLTKVDQILGNQTMLPILIYDAVVLFASSARNVIAAMQPFHPPNRHCGSSSPWMLGAFIVNEMKTISEDDVEPHFKTENMKLDEYGQRIHFNLEIYKPTVNEPMMVWTPDNGIKKRLLNLELESAGTTQDFSEQRKVYTVVTHYEEPYFMMKEDHENFRGREKYEGYAVDLISKLSELMEFDYEFMIVNGNGKYNPETKQWDGIIRKLIDHHAQIGVCDLTITQMRRSVVDFTVPFMQLGISILHYKSPPEPKNQFAFLEPFAVEVWIYMIFAQLIMTLAFVFIARLSYREWLPPNPAIQDPDELENIWNVNNSTWLMVGSIMQQGCDILPRGPHMRILTGMWWFFALMMLSTYTANLAAFLTSNKWQSSIKSLQDLIEQDKVHFGSMRGGSTSLFFSESNDTDYQRAWNQMKDFNPSAFTSTNKEGVARVRKEKGGYAFLMETTSLTYNIERNCDLTQIGEQIGEKHYGLAVPLGSDYRTNLSVSILQLSERGELQKMKNKWWKNHNVTCDSYHEVDGDELSIIELGGVFLVLAGGVLIGVILGIFEFLWNVQNVAVEERVTPWQAFKAELIFALKFWVRKKPMRISSSSDKSSSRRSSGSRRSSKEKSRSKTVS", "length": 907, "header": "tr|Q9VMP4-1|Q9VMP4_DROME Isoform 1 of Glutamate receptor IIA OS=Drosophila melanogaster OX=7227 GN=GluRIIA PE=3 SV=1 CANONICAL=Q9VMP4-1" }, "isoforms": [ { "isoform_ac": "Q9VMP4-1", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4/entry#Q9VMP4-1", "sequence": { "sequence": "MRLCPVVIYAFIIIIGFLEGIIALGGDDRNEITVGAIFYENEKEIELSFDQAFREVNNMKFSELRFVTIKRYMPTNDSFLLQQITCELISNGVAAIFGPSSKAASDIVAQIANATGIPHIEYDLKLEATRQEQLNHQMSINVAPSLSVLSRAYFEIIKSNYEWRTFTLIYETPEGLARLQDLMNIQALNSDYVKLRNLADYADDYRILWKETDETFHEQRIILDCEPKTLKELLKVSIDFKLQGPFRNWFLTHLDTHNSGLRDIYNEDFKANITSVRLKVVDANPFERKKTRLTKVDQILGNQTMLPILIYDAVVLFASSARNVIAAMQPFHPPNRHCGSSSPWMLGAFIVNEMKTISEDDVEPHFKTENMKLDEYGQRIHFNLEIYKPTVNEPMMVWTPDNGIKKRLLNLELESAGTTQDFSEQRKVYTVVTHYEEPYFMMKEDHENFRGREKYEGYAVDLISKLSELMEFDYEFMIVNGNGKYNPETKQWDGIIRKLIDHHAQIGVCDLTITQMRRSVVDFTVPFMQLGISILHYKSPPEPKNQFAFLEPFAVEVWIYMIFAQLIMTLAFVFIARLSYREWLPPNPAIQDPDELENIWNVNNSTWLMVGSIMQQGCDILPRGPHMRILTGMWWFFALMMLSTYTANLAAFLTSNKWQSSIKSLQDLIEQDKVHFGSMRGGSTSLFFSESNDTDYQRAWNQMKDFNPSAFTSTNKEGVARVRKEKGGYAFLMETTSLTYNIERNCDLTQIGEQIGEKHYGLAVPLGSDYRTNLSVSILQLSERGELQKMKNKWWKNHNVTCDSYHEVDGDELSIIELGGVFLVLAGGVLIGVILGIFEFLWNVQNVAVEERVTPWQAFKAELIFALKFWVRKKPMRISSSSDKSSSRRSSGSRRSSKEKSRSKTVS", "length": 907, "header": "tr|Q9VMP4-1|Q9VMP4_DROME Isoform 1 of Glutamate receptor IIA OS=Drosophila melanogaster OX=7227 GN=GluRIIA PE=3 SV=1 CANONICAL=Q9VMP4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VMP4", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VMP4", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMP4", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMP4", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VMP4", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VMP4", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VMP4", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMP4", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMP4", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VMP4", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VMP4", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG6992", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG6992", "resource": "KEGG Pathway" }, { "id": "R-DME-451307", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-451307", "resource": "Reactome", "description": "Activation of Na-permeable kainate receptors" }, { "id": "R-DME-451308", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-451308", "resource": "Reactome", "description": "Activation of Ca-permeable Kainate Receptor" }, { "id": "R-DME-500657", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-500657", "resource": "Reactome", "description": "Presynaptic function of Kainate receptors" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0B4KHJ0-1", "protein_name": "Grik, isoform C", "gene_name": "Grik", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MWFVKMISTEASFPLGFILTSLLLAFPGCRGERTNVGLVYENTDPDLEKIFHLAISKANEENEDLQLHGVSVSIEPGNSFETSKKLCKMLRQNLVAVFGPTSNLAARHAMSICDAKELPFLDTRWDFGAQLPTINLHPHPATLGVALRDMVVALGWESFTIIYESGEYLPTVRELLQMYGTAGPTVTVRRYELDLNGNYRNVLRRIRNADDFSFVVVGSMATLPEFFKQAQQVGLVTSDYRYIIGNLDWHTMDLEPYQHAGTNITGLRLVSPDSEQVQEVAKALYESEEPFQNVSCPLTNSMALVYDGVQLLAETYKHVNFRPVALSCNDDSAWDKGYTLVNYMKSLTLNGLTGPIRFDYEGLRTDFKLEVIELAVSGMQKIGQWSGEDGFQENRPAPAHSLEPDMRSLVNKSFVVITAISEPYGMLKETSEKLEGNDQFEGFGIELIDELSKKLGFSYTWRLQEDNKYGGIDPKTGEWNGMLREIIDSRADMGITDLTMTSERESGVDFTIPFMSLGIGILFRKPMKEPPKLFSFMSPFSGEVWLWLGLAYMGVSISMFVLGRLSPAEWDNPYPCIEEPTELENQFSFANCLWFSIGALLQQGSELAPKAYSTRAVAASWWFFTLILVSSYTANLAAFLTVESLVTPINDADDLSKNKGGVNYGAKIGGATFNFFKESNYPTYQRMYEFMRDNPQYMTNTNQEGVDRVENSNYAFLMESTTIEYITERRCTLTQVGALLDEKGYGIAMRKNWPYRDTLSQAVLEMQEQGLLTKMKTKWWQEKRGGGACSDADEDSGAVALEISNLGGVFLVMGVGSFFGIFVSLLEMVLGVKERSDENQVSFKTELLDEIRFILQCSGNTKAVKYPKNSSRSNASSKSKGSSMSVDSLPEDTSEADASGKHNHGKK", "length": 907 }, "evidence": [ { "id": "HGNC:4582", "url": "https://alliancegenome.org/gene/HGNC:4582#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-6502", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-6502#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070821-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070821-5#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070821-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070821-6#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070821-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070821-1#orthology", "database": "AGR" }, { "id": "MGI:95817", "url": "https://alliancegenome.org/gene/MGI:95817#orthology", "database": "AGR" }, { "id": "RGD:2734", "url": "https://alliancegenome.org/gene/RGD:2734#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A0A8M1P3L5-1", "protein_name": "Glutamate receptor", "gene_name": "grik5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPELPALLLSIYFRFLLVTVVTMPPSSLSQTPVLSSVRMAAILDDSSVCGRGERLALALARENINSVMENPARARVEVDIFELQKDSQYETTDTMCQILPKGVVSVIGPASSPASGSIVSHICGEKEIPHVKIGPEETPRLPYLRFASVTLYPSNEDLSLAIGSILRSFSYPSASLVCAKAECLLRLEELIRRFLISRETLSIRMLDDNLDPTPLLKEIRDDKIATIIIDANASISYLILKKASELGMTSAFYKYILTTMDFPLLWLDDIVDEQSNIVGFSMFNTTHPFYLEFIRSLNLSWREGCDINPYPGPALSSALLFDAVHVVVSAVQELNRSQEIGVKPLSCTSPQIWQHGTSLMNYLRMVEYDGLTGRVEFNSKGQRTNYTLHILEKHRGGHKEIGIWYSNNTLLMNSTSLDINVSETLANKSLIITTILENPYVMRKINYQEFEGNEQYEGFCVDMLRELSDILKFTYRIKLVDDGLYGAPEPNGSWTGMVGELINRKADLAVAAFTITSEREKVIDFSKPFMTLGISILYRVHIGRKPGYFSFLDPFSPAVWLFMLLAYLAVSCVLFLSARLSPYEWYNPHPCLRERRDLLENQYTLGNSLWFPVGGFMQQGSEIMPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMEVPIESPDDLADQTNIQYGTIHGGSTMTFFMNSRYQTYQRMWNYMYSKQPSVFVKSTEEGIARVVNSKYAFLLESTMNEYHRSLNCNLTQIGGLLDTKGYGIGMPLGSPFRDELSLAVLQLQENNRLEILKRRWWEGGKCPKEEDHRAKGLGMENIGGIFVVLICGLIIAVFVAVMEFVWSTRRSAETDEVRPLSCDRQYHSHTTVSVCQEMLTEFRNAVSCKKSSRLRRRRPLSSSLALRHPTRITLGAPRPLRLVREMRLSNGKLYSGTGPLTGGSGPGGGPTDMGPGPQRLLEDPLGANSTPAVALGPPAVTVPLPRGCTHVRICQECRRIQSLRTTSCTRIPPSSAPLPRLAPPPPHSSSNTDSEGGGGLSPCRIGHSPPAKGCSLPPPQSSNNTDLMGEQK", "length": 1067 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070821-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070821-6#orthology", "database": "AGR" }, { "id": "FB:FBgn0004620", "url": "https://alliancegenome.org/gene/FB:FBgn0004620#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3BCZ5-1", "protein_name": "Glutamate receptor", "gene_name": "grik1a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKFWLLTSFDSRAMEKRKRLLFFFFYSMAKFYLSEQQVIRIGGIFETRENEPVSMDELAFKFAVTSINRNRTLMPNTTLTYDIQRVNLFDSFEASRRVCDQLALGVAAVFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNKDNFYINLYPEYTSISRAILDIVIFYKWKCVTVVYEDSTGLMRMQELIKAPSKNNLKIRIRQLPSGGGDSRPLLKEMKKEKEFYVIFDCSYQVAAELLKQLMSMGMMTEYYHFFFTTLDLFALDLEPYRYSGVNMTAFRLLNLDDSYVASVIQKWSMERQLAPPKPESGLMSGIMTTAAALMYDAVFMVAVASQRATQMTVSSLQCHRHKPWRYGPRFMNLFKEAQWDGLTGRIVLNKTDGLRKEFNLDLISLKEDGTAKRVADGASRPNKLWTKIGVWNSYTGLNLTEIKDNKNITDSLANRTLIVTTILENPYVMYKKSDKVLYGNDRFEGYCLDLLKELSNILGFTYEVKLVTDGKYGAQNDKGEWNGMVRELIDHIADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLTPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPSSEVVENNFTLLNSLWFGVAALMRQGSELMPKALSTRILGGIWWFFTLIIISSYTANLAAFLTVERMDSPIDSADDLAKQTRIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRKNTALVKNSKDGITRVLTTDYALLMESTSIEYITQRNCNLTQVGGLIDSKGYGVGTPIGSPYRDKVTIAILQLQEEGKLHMMKEKWWRGNGCPEEDSKEASALGVENIGGIFIVLAAGLVLSVFVAIGEFIYKSHKNSDIEECVSFSAVMEDLGISLRCHKALRKRGRHRGRAGLSGVLCNPKRIPRKETMA", "length": 919 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-030131-6502", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-6502#orthology", "database": "AGR" }, { "id": "FB:FBgn0004620", "url": "https://alliancegenome.org/gene/FB:FBgn0004620#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9P799-1", "protein_name": "Glutamate receptor", "gene_name": "grik4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLAAWAPLLFLAMWVRNATSGPLSFRIAAILDDPMECSRGERLAITLAKDSINRSSNRSTTGKLEVDIFELLRDSEYETGETMCQIMSKGVVAVLGPSASPASNSIISNICGEKEVPYVKVAPEDILKVQFPRFTTLDLRPTNTDISMAVAGLLTFFNSSTSCLICAQADCLLNLEVLLRQFLISKETLSVRMLDDSQDPTPLLKEIRDDKTATIIVDANATMSHVILERASELGMLSVYYTYILTSLEFSLLRLDDLADQRVNIVGFSVFNRTHPFFQDFVLSLNRSWQENCDHAPFAGTPLSSALLFDAVHTVVAAVQELNRSQNVGATQLSCKSSKIWEHGTSLMNYLRMVELEGLTGHIEFNSKGQRSNYALRIMQNSRDGLRQIGQWHSEQGLSMERKLPSLNVTDTLFNTTLTITTILENPYVMLRANHQELEGNDRYEGFCVDMLKELADILKFKYRIRLVGDGVYGVPGANGTWTGMVGELISRKADLAVAALTITAEREKVIDFSKPFMTLGISIMYRVHIGRRPGYFSFLDPFSPGVWLFMLLAYLAVSCVLFLVARLTPYEWYNPHPCLKGRCSLLINQYSLGNSFWFPVGGFMQQGSTIAPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMEVPIESVDDLADQTAIEYGTMHGGSTMTFFQNSRYQTYQRMWNFMYSKQPSVFVKSTEEGIARVLNSNYAYLLESTMNEYYRQRNCNLTQIGGLLDTKGYGIGMPLGSVYRDEFDLAILRLQEENRLEILKRKWWDGGKCPKEEDHRAKGLGMENIGGIFVVLVCGLLVAIFMAVLEFVWMLRHTPGTELSVCEEMLRELQGIVLCQDSLQLRRRRGASVLRPQPLPLDERRARAAAASLSNGKLCTGTGLSEPLSHRLAQEAALVARGCSHIRICPECRRFQGIRVRPSGPPGASPSHSEESIEWEKGTNNSEHE", "length": 965 }, "evidence": [ { "id": "HGNC:4582", "url": "https://alliancegenome.org/gene/HGNC:4582#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070821-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070821-5#orthology", "database": "AGR" }, { "id": "MGI:95817", "url": "https://alliancegenome.org/gene/MGI:95817#orthology", "database": "AGR" }, { "id": "RGD:2734", "url": "https://alliancegenome.org/gene/RGD:2734#orthology", "database": "AGR" }, { "id": "FB:FBgn0004620", "url": "https://alliancegenome.org/gene/FB:FBgn0004620#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7TB31-1", "protein_name": "Glutamate receptor", "gene_name": "grik1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSTSASEWKDMLLGWDLFLYGYRRKTDMDVKCSSRRCALLKRTGVSFILLCLMAEVGLSAQQVLRIGGIFETLENEPISVEELAFKFAVTNINRNRTLMPNTTLTYDIQRINLFDSFEASRRACDQLALGVAAVFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNKDSFYINLYPDYASISRAVLDIVQFYKWKAVTVVYEDATGLIRLQELIKAPSRYSIKIKIRQLPTGSKDARPLLKEMKKGKEFCVIFDCSYQTAADVLKQLLSMGMMTEYYHFFFTTLDLYSLDLEPFRYSGVNMTGFRLLNIDNPQVASVVEKWSMERLQAPPKPETGLQDGMMTTEAALMYDAVYMVAAASQRASQITVSSLQCHRHKPWRFGSRFISMFKEAQWNGLTGQIIINKTDGLRKDFDLDIISLKEDGLEKPLESGRFNKVWKKIGVWNSNTGLNLTDSNKDKNTNVTDSMANRTLIVTTILENPYVMYKKSDKPLYGNDRFEGYCLDLLKELSNILGFSYEVKLVTDGKYGAQNDKGEWNGMVRELIDHVADLAVAPLTITYVREKVIDFSKPFMTLGISILYHKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPDSDVVENNFTLINSVWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMDSPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRKNTALVKNNREGIQRVLTTDYALLMESTSIEYISQRNCNLTQIGGLIDSKGYGVGTPIGSPYRDKVTIAILQLQEEGKLHMMKEKWWRGNGCPEEDSKEASALGVENIGGIFIVLAAGLVLSVFVAIGEFIYKSRKNLDIEEVSVGQCEWHNKY", "length": 906 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070821-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070821-1#orthology", "database": "AGR" }, { "id": "FB:FBgn0004620", "url": "https://alliancegenome.org/gene/FB:FBgn0004620#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P22756-1", "protein_name": "Glutamate receptor ionotropic, kainate 1", "gene_name": "Grik1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MERSTVLIQPGLWTRDTSWTLLYFLCYILPQTSPQVLRIGGIFETVENEPVNVEELAFKFAVTSINRNRTLMPNTTLTYDIQRINLFDSFEASRRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDSRDLFYINLYPDYAAISRAVLDLVLYYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPPANKDAKPLLKEMKKSKEFYVIFDCSHETAAEILKQILFMGMMTEYYHYFFTTLDLFALDLELYRYSGVNMTGFRKLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGMMTTEAALMYDAVYMVAIASHRASQLTVSSLQCHRHKPCALGPRFMNLIKEARWDGLTGRITFNKTDGLRKDFDLDIISLKEEGTEKASGEVSKHLYKVWKKIGIWNSNSGLNMTDGNRDRSNNITDSLANRTLIVTTILEEPYVMYRKSDKPLYGNDRFEAYCLDLLKELSNILGFLYDVKLVPDGKYGAQNDKGEWNGMVKELIDHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQQSALVKNSDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGGLIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGCPEEDSKEASALGVENIGGIFIVLAAGLVLSVFVAIGEFLYKSRKNNDVEQKGKSSRLRFYFRNKVRFHGSKKESLGVEKCLSFNAIMEELGISLKNQKKLKKKSRTKGKSSFTSILTCHQRRTQRKETVA", "length": 949 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-030131-6502", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-6502#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070821-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070821-1#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P39086-1", "protein_name": "Glutamate receptor ionotropic, kainate 1", "gene_name": "GRIK1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEHGTLLAQPGLWTRDTSWALLYFLCYILPQTAPQVLRIGGIFETVENEPVNVEELAFKFAVTSINRNRTLMPNTTLTYDIQRINLFDSFEASRRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNKDLFYINLYPDYAAISRAILDLVLYYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPSGNKDAKPLLKEMKKGKEFYVIFDCSHETAAEILKQILFMGMMTEYYHYFFTTLDLFALDLELYRYSGVNMTGFRLLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGMMTTEAALMYDAVYMVAIASHRASQLTVSSLQCHRHKPWRLGPRFMNLIKEARWDGLTGHITFNKTNGLRKDFDLDIISLKEEGTEKAAGEVSKHLYKVWKKIGIWNSNSGLNMTDSNKDKSSNITDSLANRTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFIYDVKLVPDGKYGAQNDKGEWNGMVKELIDHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQQTALVRNSDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGGLIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGCPEEDNKEASALGVENIGGIFIVLAAGLVLSVFVAIGEFIYKSRKNNDIEQAFCFFYGLQCKQTHPTNSTSGTTLSTDLECGKLIREERGIRKQSSVHTV", "length": 918 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-030131-6502", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-6502#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070821-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070821-1#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q01812-1", "protein_name": "Glutamate receptor ionotropic, kainate 4", "gene_name": "Grik4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPRVSAPLVLLPAWLLMVACSPHSLRIAAILDDPMECSRGERLSITLAKNRINRAPERLGKAKVEVDIFELLRDSEYETAETMCQILPKGVVAVLGPSSSPASSSIISNICGEKEVPHFKVAPEEFVRFQLQRFTTLNLHPSNTDISVAVAGILNFFNCTTACLICAKAECLLNLEKLLRQFLISKDTLSVRMLDDTRDPTPLLKEIRDDKTATIIIHANASMSHTILLKAAELGMVSAYYTYIFTNLEFSLQRMDSLVDDRVNILGFSIFNQSHAFFQEFSQSLNQSWQENCDHVPFTGPALSSALLFDAVYAVVTAVQELNRSQEIGVKPLSCGSAQIWQHGTSLMNYLRMVELEGLTGHIEFNSKGQRSNYALKILQFTRNGFRQIGQWHVAEGLSMDSRLYASNISDSLFNTTLVVTTILENPYLMLKGNHQDMEGNDRYEGFCVDMLKELAEILRFNYKIRLVGDGVYGVPEANGTWTGMVGELIARKADLAVAGLTITAEREKVIDFSKPFMTLGISILYRVHMGRRPGYFSSLDPFSPGVWLFMLLAYLAVSCVLFLVARLTPYEWYSPHPCAQGRCNLLVNQYSLGNSLWFPVGGFMQQGSTIAPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMEVPIESVDDLADQTAIEYGTIHGGSSMTFFQNSRYQTYQRMWNYMYSKQPSVFVKSTEEGIARVLNSNYAFLLESTMNEYYRQRNCNLTQIGGLLDTKGYGIGMPVGSVFRDEFDLAILQLQENNRLEILKRKWWEGGKCPKEEDHRAKGLGMENIGGIFVVLICGLIVAIFMAMLEFLWTLRHSEASEVSVCQEMMTELRSIILCQDNIHPRRRRSGGLPPQPPVLEERRPRGTATLSNGKLCGAGEPDQLAQRLAQEAALVARGCTHIRVCPECRRFQGLRARPSPARSEESLEWDKTTNSSEPE", "length": 956 }, "evidence": [ { "id": "HGNC:4582", "url": "https://alliancegenome.org/gene/HGNC:4582#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070821-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070821-5#orthology", "database": "AGR" }, { "id": "MGI:95817", "url": "https://alliancegenome.org/gene/MGI:95817#orthology", "database": "AGR" }, { "id": "RGD:2734", "url": "https://alliancegenome.org/gene/RGD:2734#orthology", "database": "AGR" }, { "id": "FB:FBgn0004620", "url": "https://alliancegenome.org/gene/FB:FBgn0004620#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q0E8N6-1", "protein_name": "Clumsy, isoform B", "gene_name": "clumsy", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MYSLFLTHFLLIALPVLADIDRSQFMVGSIFTSDKDESEIAFRTAVDRANILERNVELVPIVVYANTDDSFIMEKMVCNLISQGVIAIFGPSTGSSSDIIASICDTLDIPHIVYDWIPNESIPDREHSTMTLNVHPDNLLLSQGLAEIVQSFAWRSFTVVYETDKELQQLQDILQVGEPISNPTTVKQLGPGDDHRPFLKEIKLSTDNCLILHCAPDNLLKILQQANELKMLGEYQSVFIPLLDTHSIDFGELSGVEANITTVRLMDPSDFHVKNVVHDWEEREKREGRYFKVDPNRVKSQMILLNDAVWLFSKGLTELGIFEELTAPDLECRRKKPWPFGKRIIEFIKARSEETSTGRIDFNENGQRSFFTLRFMELNSDGFLDLATWDPVNGLDVLNDDEESEKRVGQKLSNKTFIVSSRLGAPFLTLREPQEGEILTGNSRYEGYSIDLINEIAKMLNFKFEFRMSPDGKYGALNKVTQTWDGIVRQLIDGNADLGICDLTMTSSRRQAVDFTPPFMTLGISILFSKPPTPPTDLFSFLSPFSLDVWIYMGSAYLFISLLLFALARMAPDDWENPHPCKEPEEVENIWSIMNTTWLSIGSLMGQGCDILPKAASTRLVTGMWWFFALMMLNSYTANLAAFLTNSRQANSINSAEDLAAQSKIKYGAMAGGSTMGFFRDSNFSTYQKMWTAMESASPSVFTKTNDEGVERVQKGKNLYAFLMESTTLEYNVERKCDLVQIGGWLDYKSYGIAMPFNSPYRKQISAAVLKLGELGQLAELKRKWWKEMHGGGNCEKSDEDGGDTPELGLENVGGVFLVLGLGLLSAMVLGCTEFLWNVKSVAIEEKISLKEAFKSEALFAARIWITTKPVHTSSESGSSNSSSSSSSRSKHSFKSQGLSMKSLKSSGYQDVEASVHSKLKKIGSMFSLKSQKTVTPPPEIGWKLDKSTQIDVVPTSDVDQELIPEVEPHLPHRHHHHHHHRHHHHHHQPDQEHDRNPSPPE", "length": 1002 }, "evidence": [ { "id": "HGNC:4582", "url": "https://alliancegenome.org/gene/HGNC:4582#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-6502", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-6502#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070821-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070821-5#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070821-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070821-6#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070821-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070821-1#orthology", "database": "AGR" }, { "id": "MGI:95817", "url": "https://alliancegenome.org/gene/MGI:95817#orthology", "database": "AGR" }, { "id": "RGD:2734", "url": "https://alliancegenome.org/gene/RGD:2734#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q0KI42-1", "protein_name": "Glutamate receptor IIE", "gene_name": "GluRIIE", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFFNHFVILWSLFSIHISVNWAQYENFGGYDNYQSLESVPIGLLTDQNTEQMNIVFDHAIDVANQEVGTSLTSLKEEVNYGDAYQSYGKLCRMLETGIAGVFGPSSRHTAVHLMSICDAMDIPHIYSYMSENAEGFNLHPHPADLAKALYSLITEFNWTRFIFLYESAEYLNILNELTTMLGKSGTVITVLRYDMQLNGNYKQVLRRVRKSVDNRIVVVGSSETMPEFLNQAQQVGIINEDYKYIIGNLDFHSFDLEEYKYSEANITGLRLFSPEKMAVKELLMKLGYPTDQDEFRNGSCPITVEMALTYDAVQLFAQTLKNLPFKPMPQNCSQRTESVRDDGSSFKNYMRTLRLTDRLLTGPIYFEGNVRKGYHLDVIELQPSGIVKVGTWDEDRQYRPQRLAPTTAQFDSVDNSLANKTFIILLSVPNKPYAQLVETYKQLEGNSQYEGYGVDLIKELADKLGFNFTFVNGGNDYGSYNKSTNESTGMLREIMTGRADLAITDLTITSEREQALDFTIPFMNLGIAILYLKPQKATPELFTFMDPFSEEVWWFLGFSFLGVSLSFFILGRLSPSEWDNPYPCIEEPEELENQFTLGNSIWFTTGALLQQGSEIGPKALSTRTVASFWWFFTLIVVSSYTANLAAFLTIEKPQSLINSVDDLADNKDGVVYGAKKTGSTRNFFMTSAEERYKKMNKFMSENPQYLTEDNMEGVNRVKTNTHYAFLMESTSIEYNTKRECNLKKIGDALDEKGYGIAMRKDWPHRGKFNNALLELQEQGVLEKMKNKWWNEVGTGICATKEDAPDATPLDMNNLEGVFFVLLVGSCCALLYGIISWVLFVMKKAHHYRVPLRDALKEEFQFVIDFNNYVRVLKNSASIYSRSRQSSMSVASVAQESQ", "length": 897 }, "evidence": [ { "id": "HGNC:4582", "url": "https://alliancegenome.org/gene/HGNC:4582#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-6502", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-6502#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070821-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070821-1#orthology", "database": "AGR" }, { "id": "MGI:95817", "url": "https://alliancegenome.org/gene/MGI:95817#orthology", "database": "AGR" }, { "id": "RGD:2734", "url": "https://alliancegenome.org/gene/RGD:2734#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q0KIF2-1", "protein_name": "Eye-enriched kainate receptor, isoform B", "gene_name": "Ekar", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLIASGFLLFQFLSYGLGVPPLVRIGAIFSNQPGMYNSELAFRYAIHRLNMDKSLLPETTVDYYVEYVNRFDSFETVQKVCKLIRVGVQAVFSPTDSVLATHINSICDALDIPNIGRSAHDFSINVYPSKQLVNYAFNDVIQYLNWTRFGILHEKENGIINLHQLSRSFHGEVHMRQVSRDSYVSALNEFKGKEIHNIIIDTNSNGISILLKNILQQQMNEYKYHYLFTSFDLETYDLEDFKYNFVNITSFRLVDTADVGVKQILKDIGLYSHHIFKKPYLNLHIKKSTILESEPALMFDSVYVFAIGLQTLEQSHSLTLLNISCEEENSWDGGLSLINYLNAVEWKGLTGPIQFKDGQRVQFKLDLIKLKQHSIVKVGEWTPHGHLNITEPSMFFDAGSMNVTLVVITILETPYVMMHYGKNFTGNERFYGFCVDILETISREVGFDYILDLVPDRKYGAKDPETGEWNGMVAQLMKYKADLAVGSMTITYARESVIDFTKPFMNLGISILFKVPTSEPTRLFSFMNPLAIEIWIYVLIAYFLVSLCIYIVGKLSPIEWKCINACDLENISIGNQFSLTDSFWFTIGTFMQQSPDIYPRAMSTRIISSTWGFFSLIIVASYTANLAAFLTTERMINPIENAEDLASQTEISYGTLDSGSTMTFFRDSVIETYKKIWRSMDNKKPSAFTTTYEDGIKRVNQGNYAFLMESTMLDYIVQRDCNLTQIGGLLDTKGYGIATPKGSPWRDKISLAILELQERGDIQMLYDKWWKNTDETCTRKNTSKQSKANSLGLESIGGVFVVLIAGIIVAAVVAFFEFWYNFRYNYEATPSQSVVNNKYNQDGILESERNYTPPDRSFWIEIAEELRYASWCMNKQKRPALTRTCSKCTIPKGQRINKL", "length": 899 }, "evidence": [ { "id": "HGNC:4582", "url": "https://alliancegenome.org/gene/HGNC:4582#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-6502", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-6502#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070821-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070821-5#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070821-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070821-6#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070821-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070821-1#orthology", "database": "AGR" }, { "id": "MGI:95817", "url": "https://alliancegenome.org/gene/MGI:95817#orthology", "database": "AGR" }, { "id": "RGD:2734", "url": "https://alliancegenome.org/gene/RGD:2734#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q16099-1", "protein_name": "Glutamate receptor ionotropic, kainate 4", "gene_name": "GRIK4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPRVSAPLVLLPAWLVMVACSPHSLRIAAILDDPMECSRGERLSITLAKNRINRAPERLGKAKVEVDIFELLRDSEYETAETMCQILPKGVVAVLGPSSSPASSSIISNICGEKEVPHFKVAPEEFVKFQFQRFTTLNLHPSNTDISVAVAGILNFFNCTTACLICAKAECLLNLEKLLRQFLISKDTLSVRMLDDTRDPTPLLKEIRDDKTATIIIHANASMSHTILLKAAELGMVSAYYTYIFTNLEFSLQRMDSLVDDRVNILGFSIFNQSHAFFQEFAQSLNQSWQENCDHVPFTGPALSSALLFDAVYAVVTAVQELNRSQEIGVKPLSCGSAQIWQHGTSLMNYLRMVELEGLTGHIEFNSKGQRSNYALKILQFTRNGFRQIGQWHVAEGLSMDSHLYASNISDTLFNTTLVVTTILENPYLMLKGNHQEMEGNDRYEGFCVDMLKELAEILRFNYKIRLVGDGVYGVPEANGTWTGMVGELIARKADLAVAGLTITAEREKVIDFSKPFMTLGISILYRVHMGRKPGYFSFLDPFSPGVWLFMLLAYLAVSCVLFLVARLTPYEWYSPHPCAQGRCNLLVNQYSLGNSLWFPVGGFMQQGSTIAPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMDVPIESVDDLADQTAIEYGTIHGGSSMTFFQNSRYQTYQRMWNYMYSKQPSVFVKSTEEGIARVLNSNYAFLLESTMNEYYRQRNCNLTQIGGLLDTKGYGIGMPVGSVFRDEFDLAILQLQENNRLEILKRKWWEGGKCPKEEDHRAKGLGMENIGGIFVVLICGLIVAIFMAMLEFLWTLRHSEATEVSVCQEMVTELRSIILCQDSIHPRRRRAAVPPPRPPIPEERRPRGTATLSNGKLCGAGEPDQLAQRLAQEAALVARGCTHIRVCPECRRFQGLRARPSPARSEESLEWEKTTNSSEPE", "length": 956 }, "evidence": [ { "id": "HGNC:4582", "url": "https://alliancegenome.org/gene/HGNC:4582#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070821-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070821-5#orthology", "database": "AGR" }, { "id": "MGI:95817", "url": "https://alliancegenome.org/gene/MGI:95817#orthology", "database": "AGR" }, { "id": "RGD:2734", "url": "https://alliancegenome.org/gene/RGD:2734#orthology", "database": "AGR" }, { "id": "FB:FBgn0004620", "url": "https://alliancegenome.org/gene/FB:FBgn0004620#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q16478-1", "protein_name": "Glutamate receptor ionotropic, kainate 5", "gene_name": "GRIK5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPAELLLLLIVAFASPSCQVLSSLRMAAILDDQTVCGRGERLALALAREQINGIIEVPAKARVEVDIFELQRDSQYETTDTMCQILPKGVVSVLGPSSSPASASTVSHICGEKEIPHIKVGPEETPRLQYLRFASVSLYPSNEDVSLAVSRILKSFNYPSASLICAKAECLLRLEELVRGFLISKETLSVRMLDDSRDPTPLLKEIRDDKVSTIIIDANASISHLILRKASELGMTSAFYKYILTTMDFPILHLDGIVEDSSNILGFSMFNTSHPFYPEFVRSLNMSWRENCEASTYLGPALSAALMFDAVHVVVSAVRELNRSQEIGVKPLACTSANIWPHGTSLMNYLRMVEYDGLTGRVEFNSKGQRTNYTLRILEKSRQGHREIGVWYSNRTLAMNATTLDINLSQTLANKTLVVTTILENPYVMRRPNFQALSGNERFEGFCVDMLRELAELLRFRYRLRLVEDGLYGAPEPNGSWTGMVGELINRKADLAVAAFTITAEREKVIDFSKPFMTLGISILYRVHMGRKPGYFSFLDPFSPAVWLFMLLAYLAVSCVLFLAARLSPYEWYNPHPCLRARPHILENQYTLGNSLWFPVGGFMQQGSEIMPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMEVPVESADDLADQTNIEYGTIHAGSTMTFFQNSRYQTYQRMWNYMQSKQPSVFVKSTEEGIARVLNSRYAFLLESTMNEYHRRLNCNLTQIGGLLDTKGYGIGMPLGSPFRDEITLAILQLQENNRLEILKRKWWEGGRCPKEEDHRAKGLGMENIGGIFIVLICGLIIAVFVAVMEFIWSTRRSAESEEVSVCQEMLQELRHAVSCRKTSRSRRRRRPGGPSRALLSLRAVREMRLSNGKLYSAGAGGDAGSAHGGPQRLLDDPGPPSGARPAAPTPCTHVRVCQECRRIQALRASGAGAPPRGLGVPAEATSPPRPRPGPAGPRELAEHE", "length": 980 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070821-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070821-6#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q60934-1", "protein_name": "Glutamate receptor ionotropic, kainate 1", "gene_name": "Grik1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERGTVLIQPGLWTRDTSWTLLYFLCYILPQTSPQVLRIGGIFETVENEPVNVEELAFKFAVTSINRNRTLMPNTTLTYDIQRINLFDSFEASRRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNRDLFYINLYPDYAAISRAVLDLVLYYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPSGNKDAKPLLKEMKKGKEFYVIFDCSHETAAEILKQILFMGMMTEYYHYFFTTLDLFALDLELYRYSGVNMTGFRLLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGVMTTEAALMYDAVYMVAIASHRASQLTVSSLQCHRHKPWRLGPRFMNLIKEARWDGLTGRITFNKTDGLRKDFDLDIISLKEEGTEKIGIWNSNSGLNMTDGNRDRSNNITDSLANRTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFLYDVKLVPDGKYGAQNDKGEWNGMVKELIDHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQPSALGVENIGGIFIVLAAGLVLSVFVAIGEFIYKSRKNNDIEQKGKSSRLRFYFRNKVRFHGSKTESLGVEKCLSFNAIMEELGISLKNQKKIKKKSRTKGKSSFTSILTCHQRRTQRKETVA", "length": 836 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-030131-6502", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-6502#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070821-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070821-1#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q61626-1", "protein_name": "Glutamate receptor ionotropic, kainate 5", "gene_name": "Grik5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPAELLLLLIVAFANPSCQVLSSLRMAAILDDQTVCGRGERLALALAREQINGIIEVPAKARVEVDIFELQRDSQYETTDTMCQILPKGVVSVLGPSSSPASASTVSHICGEKEIPHIKVGPEETPRLQYLRFASVSLYPSNEDVSLAVSRILKSFNYPSASLICAKAECLLRLEELVRGFLISKETLSVRMLDDSRDPTPLLKEIRDDKVSTIIIDANASISHLVLRKASELGMTSAFYKYILTTMDFPILHLDGIVEDSSNILGFSMFNTSHPFYPEFVRSLNMSWRENCEASTYPGPALSAALMFDAVHVVVSAVRELNRSQEIGVKPLACTSANIWPHGTSLMNYLRMVEYDGLTGRVEFNSKGQRTNYTLRILEKSRQGHREIGVWYSNRTLAMNATTLDINLSQTLANKTLVVTTILENPYVMRRPNFQALSGNERFEGFCVDMLRELAELLRFRYRLRLVEDGLYGAPEPNGSWTGMVGELINRKADLAVAAFTITAEREKVIDFSKPFMTLGISILYRVHMGRKPGYFSFLDPFSPAVWLFMLLAYLAVSCVLFLAARLSPYEWYNPHPCLRARPHILENQYTLGNSLWFPVGGFMQQGSEIMPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMEVPVESADDLADQTNIEYGTIHAGSTMTFFQNSRYQTYQRMWNYMQSKQPSVFVKSTEEGIARVLNSRYAFLLESTMNEYHRRLNCNLTQIGGLLDTKGYGIGMPLGSPFRDEITLAILQLQENNRLEILKRKWWEGGRCPKEEDHRAKGLGMENIGGIFVVLICGLIIAVFVAVMEFIWSTRRSAESEEVSVCQEMLQELRHAVSCRKTSRSRRRRRPGGPSRALLSLRAVREMRLSNGKLYSAGAGGDAGAHGGPQRLLDDPGPPGGPRPQAPTPCTHVRVCQECRRIQALRASGAGAPPRGLGTPAEATSPPRPRPGPTGPRELTEHE", "length": 979 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070821-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070821-6#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q63273-1", "protein_name": "Glutamate receptor ionotropic, kainate 5", "gene_name": "Grik5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPAELLLLLIVAFANPSCQVLSSLRMAAILDDQTVCGRGERLALALAREQINGIIEVPAKARVEVDIFELQRDSQYETTDTMCQILPKGVVSVLGPSSSPASASTVSHICGEKEIPHIKVGPEETPRLQYLRFASVSLYPSNEDVSLAVSRILKSFNYPSASLICAKAECLLRLEELVRGFLISKETLSVRMLDDSRDPTPLLKEIRDDKVSTIIIDANASISHLVLRKASELGMTSAFYKYILTTMDFPILHLDGIVEDSSNILGFSMFNTSHPFYPEFVRSLNMSWRENCEASTYPGPALSAALMFDAVHVVVSAVRELNRSQEIGVKPLACTSANIWPHGTSLMNYLRMVEYDGLTGRVEFNSKGQRTNYTLRILEKSRQGHREIGVWYSNRTLAMNATTLDINLSQTLANKTLVVTTILENPYVMRRPNFQALSGNERFEGFCVDMLRELAELLRFRYRLRLVEDGLYGAPEPNGSWTGMVGELINRKADLAVAAFTITAEREKVIDFSKPFMTLGISILYRVHMGRKPGYFSFLDPFSPAVWLFMLLAYLAVSCVLFLAARLSPYEWYNPHPCLRARPHILENQYTLGNSLWFPVGGFMQQGSEIMPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMEVPVESADDLADQTNIEYGTIHAGSTMTFFQNSRYQTYQRMWNYMQSKQPSVFVKSTEEGIARVLNSRYAFLLESTMNEYHRRLNCNLTQIGGLLDTKGYGIGMPLGSPFRDEITLAILQLQENNRLEILKRKWWEGGRCPKEEDHRAKGLGMENIGGIFVVLICGLIIAVFVAVMEFIWSTRRSAESEEVSVCQEMLQELRHAVSCRKTSRSRRRRRPGGPSRALLSLRAVREMRLSNGKLYSAGAGGDAGAHGGPQRLLDDPGPPGGPRPQAPTPCTHVRVCQECRRIQALRASGAGAPPRGLGTPAEATSPPRPRPGPTGPRELTEHE", "length": 979 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070821-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070821-6#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BMF5-1", "protein_name": "Glutamate receptor ionotropic, kainate 4", "gene_name": "Grik4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRVSAPLVLLPAWLLMVACSPHSLRIAAILDDPMECSRGERLSITLAKNRINRAPERLGKAKVEVDIFELLRDSEYETAETMCQILPKGVVAVLGPSSSPASSSIISNICGEKEVPHFKVAPEEFVRFQLQRFTTLNLHPSNTDISVAVAGILNFFNCTTACLICAKAECLLNLEKLLRQFLISKDTLSVRMLDDTRDPTPLLKEIRDDKTATIIIHANASMSHTILLKAAELGMVSAYYTYIFTNLEFSLQRMDSLVDDRVNILGFSIFNQSHAFFQEFSQSLNQSWQENCDHVPFTGPALSSALLFDAVYAVVTAVQELNRSQEIGVKPLSCGSAQIWQHGTSLMNYLRMVELEGLTGHIEFNSKGQRSNYALKILQFTRNGFQQIGQWHVAEGLSMDSRLYASNISDSLFNTTLVVTTILENPYLMLKGNHQEMEGNDRYEGFCVDMLKELAEILRFNYKIRLVGDGVYGVPEANGTWTGMVGELIARKADLAVAGLTITAEREKVIDFSKPFMTLGISILYRVHMGRRPGYFSFLDPFSPGVWLFMLLAYLAVSCVLFLVARLTPYEWYSPHPCAQGRCNLLVNQYSLGNSLWFPVGGFMQQGSTIAPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMEVPIESVDDLADQTAIEYGTIHGGSSMTFFQNSRYQTYQRMWNYMYSKQPSVFVKSTEEGIARVLNSNYAFLLESTMNEYYRQRNCNLTQIGGLLDTKGYGIGMPVGSVFRDEFDLAILQLQENNRLEILKRKWWEGGKCPKEEDHRAKGLGMENIGGIFVVLICGLIVAIFMAMLEFLWTLRHSEASEVSVCQEMVTELRNIILCQDNIHPRRRRSGGLPPQPPVLEERRPRGTATLSNGKLCGAGEPDQLAQRLAQEAALVARGCTHIRVCPECRRFQGLRARPSPARSEESLEWDKTTNSSEPE", "length": 956 }, "evidence": [ { "id": "HGNC:4582", "url": "https://alliancegenome.org/gene/HGNC:4582#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070821-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070821-5#orthology", "database": "AGR" }, { "id": "MGI:95817", "url": "https://alliancegenome.org/gene/MGI:95817#orthology", "database": "AGR" }, { "id": "RGD:2734", "url": "https://alliancegenome.org/gene/RGD:2734#orthology", "database": "AGR" }, { "id": "FB:FBgn0004620", "url": "https://alliancegenome.org/gene/FB:FBgn0004620#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9V4A0-1", "protein_name": "Glutamate receptor ionotropic, kainate 2", "gene_name": "ukar", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVRKKREIVIKENIQGRSYLKKICCSYIILSILVISNALPPVIRVGAIFTEDERESSIESAFKYAIYRINKEKTLLPNTQLVYDIEYVPRDDSFRTTKKVCSQLEAGVQAIFGPTDALLASHVQSICEAYDIPHIEGRIDLEYNSKEFSINLYPSHTLLTLAYRDIMVYLNWTKVAIIYEEDYGLFNLMHSSTETKAEMYIRQASPDSYRQVLRAIRQKEIYKIIVDTNPSHIKSFFRSILQLQMNDHRYHYMFTTFDLETYDLEDFRYNSVNITAFRLVDVDSKRYLEVINQMQKLQHNGLDTINGSPYIQTESALMFDSVYAFANGLHFLNLDNHQNFYIKNLSCTSDQTWNDGISLYNQINAAITDGLTGTVQFVEGRRNIFKLDILKLKQEKIQKVGYWHPDDGVNISDPTAFYDSNIANITLVVMTREERPYVMVKEDKNLTGNLRFEGFCIDLLKAIATQVGFQYKIELVPDNMYGVYIPETNSWNGIVQELMERRADLAVASMTINYARESVIDFTKPFMNLGIGILFKVPTSQPTRLFSFMNPLAIEIWLYVLAAYILVSFALFVMARFSPYEWKNPHPCYKETDIVENQFSISNSFWFITGTFLRQGSGLNPKATSTRIVGGCWFFFCLIIISSYTANLAAFLTVERMISPIESASDLAEQTEISYGTLEGGSTMTFFRDSKIGIYQKMWRYMENRKTAVFVKTYEDGIKRVMEGSYAFLMESTMLDYAVQRDCNLTQIGGLLDSKGYGIATPKGSPWRDKISLAILELQEKGIIQILYDKWWKNTGDVCNRDDKSKESKANALGVENIGGVFVVLLCGLALAVVVAIFEFCWNSRKNLNTENQSLCSEMAEELRFAMHCHGSKSRHRPRKRSCLNCSSVPTYVPSNVSTSNVGVYYNYFN", "length": 910 }, "evidence": [ { "id": "HGNC:4582", "url": "https://alliancegenome.org/gene/HGNC:4582#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-6502", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-6502#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070821-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070821-1#orthology", "database": "AGR" }, { "id": "MGI:95817", "url": "https://alliancegenome.org/gene/MGI:95817#orthology", "database": "AGR" }, { "id": "RGD:2734", "url": "https://alliancegenome.org/gene/RGD:2734#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VDH5-1", "protein_name": "Glutamate receptor 1", "gene_name": "KaiR1D", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRSSGVLVLPLLLLQLILNCRKAQSLPDIIKIGGLFHPADDHQELAFRQAVDRINADRSILPRSKLVAQIERISPFDSFHAGKRVCGLLNIGVAAIFGPQSSHTASHVQSICDNMEIPHLENRWDYRLRRESCLVNLYPHPNTLSKAYVDIVRHWGWKTFTIIYENNDGIVRLQELLKAHGMTPFPITVRQLSDSGDYRPLLKQIKNSAEAHIVLDCSTERIHEVLKQAQQIGMMSDYHSYLVTSLDLHTVNLDEFRYGGTNITGFRLINEKIVSDVVRQWSIDEKGLLRSANLTTVRSETALMYDAVHLFAKALHDLDTSQQIDIHPISCDGQSTWQHGFSLINYMKIVEMKGLTNVIKFDHQGFRTDFMLDIVELTPAGIRKIGTWNSTLPDGINFTRTFSQKQQEIEANLKNKTLVVTTILSNPYCMRKESAIPLSGNDQFEGYAVDLIHEISKSLGFNYKIQLVPDGSYGSLNKLTGEWNGMIRELLEQRADLAIADLTITFEREQAVDFTTPFMNLGVSILYRKPIKQPPNLFSFLSPLSLDVWIYMATAYLGVSVLLFILAKFTPYEWPAYTDAHGEKVESQFTLLNCMWFAIGSLMQQGCDFLPKALSTRMVAGIWWFFTLIMISSYTANLAAFLTVERMDSPIESAEDLAKQTRIKYGALKGGSTAAFFRDSKISTYQRMWSFMESARPSVFTASNGEGVERVAKGKGSYAFLMESTSIEYVTERNCELTQVGGMLDTKSYGIATPPNSPYRTAINSVILKLQEEGKLHILKTKWWKEKRGGGKCRVETSKSSSAANELGLANVGGVFVVLMGGMGVACVIAVCEFVWKSRKVAVEERLSAILNE", "length": 853 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-030131-6502", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-6502#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070821-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070821-1#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VMP3-1", "protein_name": "Glutamate receptor IIB", "gene_name": "GluRIIB", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MHGLQFLVLLALAIASGANEDTLVIKIGAIFFDTEMKLADAFSAALEEVNAINPALKLDAIKRYVTVDDSIVLQDISCDLIGSGVAAIFGPSSKTNSDIVEVLCNMTGIPHLQFDWHPQQSNRERMNHQLTVNVAPMELFLSAAFSDILASKTFDWKSFTIAYERSSHLIRLQHILAWKQLHKAGIKMQEFERGDDYRILWKRINNAREKFVLLDCPSDILVDVINASIGYNMTGSFNHLFLTNLDTHLSGIDGFYSRDFTVAVAAVRIRTYVPPPVHDEIDVFDNSVDTRFSSLGSQLVYDSIVLFYNALLEISQRPGFYIPNFSCGRGFWQPGPRLVEQMKQITPKMVKPPFKTQRLQINADGQREDFNLEVYNPIIDRVTHIWNKEFQLVDFEKLRENSTQALKQKRLQNKEDFSQKPIRYTVATRVGKPYFSWREEPEGVHYEGNERFEGYAVDLIYMLAQECKFDFNFEPVRDNKYGSYDANTDEWDGIIRQLIDNNAQIGICDLTITQARRSVVDFTVPFMQLGISILSYKEPPPKADIYAFLNPYNAEVWLFVMIAMMITAFALIFTGRIDQYEWDQPVENVNREMERQNIWHLSNALWLVLGSMLNQGCDLLPRGLPMRLLTAFWWIFALLISQTYIAKLAAFITSSKIAGDIGSLHDLVDQNKVQFGTIRGGATSVYFSESNDTDNRMAWNKMLSFKPDAFTKNNEEGVDRVKLSKGTYAFLMETTNLQYYVQRNCELTQIGESFGEKHYGIAVPLNADFRSNLSVGILRLSERGELFKLRNKWFNSNESTCDSNVPTIDDGQFDMDSVGGLFVVLIVGVVVGLVIGVAEFLWHVQRISVKEKIPPMLALKAEFYFVIRFWLTRKPLHTYRQSRDSTSTGYSSLEQITSASSAKKKKKTRRIEK", "length": 913 }, "evidence": [ { "id": "HGNC:4582", "url": "https://alliancegenome.org/gene/HGNC:4582#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-6502", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-6502#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070821-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070821-5#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070821-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070821-6#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070821-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070821-1#orthology", "database": "AGR" }, { "id": "MGI:95817", "url": "https://alliancegenome.org/gene/MGI:95817#orthology", "database": "AGR" }, { "id": "RGD:2734", "url": "https://alliancegenome.org/gene/RGD:2734#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VPV3-1", "protein_name": "Glutamate receptor IIC", "gene_name": "GluRIIC", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MWQRILLLGCMWSAFFMCRSRGQQINIGAFFYDDELELEKEFMTVVNAINGPESEQTMRFYPLIKRLKPEDGSVTMQEHACDLIDNGVAAIFGPSSKAASDIVALVCNSTGIPHIEFDISDEGIQAEKPNHQMTLNLYPAQAILSKAYADIVQNFGWRKFTIVYDADDARAAARLQDLLQLREVHNDVVRVRKFHKDDDFRVMWKSIRGERRVVLDCEPNMLVELLNSSTEFGLTGQYNHIFLTNLETYTDHLEELAADNETFAVNITAARLLVNPDPPPYSLPYGYVTQRDNIVYESSDPPRTLIHDLIHDALQLFAQSWRNASFFYPDRMVVPRITCDFAASGGRTWAMGRYLARLMKGTSGVNNTNFRTSILQFDEDGQRITFNIEVYDPLDGIGIAIWDPRGQITQLNVDVKAQKKMIYRVATRIGPPYFSYNETARELNLTGNALYQGYAVDLIDAIARHVGFEYVFVPVADQQYGKLDKETKQWNGIIGEIINNDAHMGICDLTITQARKTAVDFTVPFMQLGVSILAYKSPHVEKTLDAYLAPFGGEVWIWILISVFVMTFLKTIVARISKMDWENPHPCNRDPEVLENQWRIHNTGWLTVASIMTAGCDILPRSPQVRMFEATWWIFAIIIANSYTANLAAFLTSSKMEGSIANLKDLSAQKKVKFGTIYGGSTYNLLADSNETVYRLAFNLMNNDDPSAYTKDNLEGVDRVRKNRGDYMFLMETTTLEYHREQNCDLRSVGEKFGEKHYAIAVPFGAEYRSNLSVAILKLSERGELYDLKQKWWKNPNASCFEEPDPDATPDMTFEELRGIFYTLYAGILIAFLIGITEFLVYVQQVALEERLTFKDAFKKEIRFVLCVWNNRKPIVAGTPISSVRTTPRRSLDKSLDRTPKSSRRVVIGRSSEEMREMAQGSGSSSGSNNAGRGEKEARV", "length": 940 }, "evidence": [ { "id": "HGNC:4582", "url": "https://alliancegenome.org/gene/HGNC:4582#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-6502", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-6502#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070821-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070821-5#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070821-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070821-6#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070821-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070821-1#orthology", "database": "AGR" }, { "id": "MGI:95817", "url": "https://alliancegenome.org/gene/MGI:95817#orthology", "database": "AGR" }, { "id": "RGD:2734", "url": "https://alliancegenome.org/gene/RGD:2734#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "glutamate-gated calcium ion channel activity", "id": "GO:0022849", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022849", "evidence": [ { "database": "UniProtKB", "id": "Q9VMP4", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ], "pmid": "" }, { "name": "glutamate-gated receptor activity", "id": "GO:0004970", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004970", "evidence": [ { "database": "UniProtKB", "id": "Q9VMP4", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ], "pmid": "" }, { "name": "transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential", "id": "GO:1904315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904315", "evidence": [ { "database": "UniProtKB", "id": "Q9VMP4", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ], "pmid": "" }, { "name": "glutamate receptor activity", "id": "GO:0008066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008066", "evidence": [ { "database": "UniProtKB", "id": "Q9VMP4", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "ionotropic glutamate receptor complex", "id": "GO:0008328", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008328", "evidence": [ { "database": "UniProtKB", "id": "Q9VMP4", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VMP4", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ], "pmid": "" }, { "name": "neuromuscular junction", "id": "GO:0031594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031594", "evidence": [ { "database": "UniProtKB", "id": "Q9VMP4", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ], "pmid": "" }, { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "Q9VMP4", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ], "pmid": "" }, { "name": "postsynaptic density membrane", "id": "GO:0098839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098839", "evidence": [ { "database": "UniProtKB", "id": "Q9VMP4", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ], "pmid": "" }, { "name": "muscle cell postsynaptic specialization", "id": "GO:0097482", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097482", "evidence": [ { "database": "UniProtKB", "id": "Q9VMP4", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "neuromuscular synaptic transmission", "id": "GO:0007274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007274", "evidence": [ { "database": "UniProtKB", "id": "Q9VMP4", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ], "pmid": "" }, { "name": "calcium ion transport", "id": "GO:0006816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006816", "evidence": [ { "database": "UniProtKB", "id": "Q9VMP4", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ], "pmid": "" }, { "name": "chemical synaptic transmission", "id": "GO:0007268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007268", "evidence": [ { "database": "UniProtKB", "id": "Q9VMP4", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ], "pmid": "" }, { "name": "synaptic transmission, glutamatergic", "id": "GO:0035249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035249", "evidence": [ { "database": "UniProtKB", "id": "Q9VMP4", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ], "pmid": "" }, { "name": "regulation of neurotransmitter secretion", "id": "GO:0046928", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046928", "evidence": [ { "database": "UniProtKB", "id": "Q9VMP4", "url": "https://www.uniprot.org/uniprotkb/Q9VMP4" } ], "pmid": "" }, { "name": 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"ventricular septal defect 2", "description": "Any ventricular septal defect in which the cause of the disease is a mutation in the CITED2 gene." }, { "id": "MONDO:0013748", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013748", "name": "CITED2 ventricular septal defect (disease)", "description": "" }, { "id": "MONDO:0013748", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013748", "name": "ventricular septal defect (disease) caused by mutation in CITED2", "description": "" }, { "id": "MONDO:0013748", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013748", "name": "ventricular septal defect 2", "description": "" }, { "id": "MONDO:0013748", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013748", "name": "ventricular septal defect type 2", "description": "" }, { "id": "MONDO:0013748", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013748", "name": "VSD2", "description": "" }, { "id": "MONDO:0013749", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013749", "name": "ventricular septal defect 3", "description": "Any ventricular septal defect in which the cause of the disease is a mutation in the NKX2-5 gene." }, { "id": "MONDO:0013749", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013749", "name": "NKX2-5 ventricular septal defect (disease)", "description": "" }, { "id": "MONDO:0013749", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013749", "name": "ventricular septal defect (disease) caused by mutation in NKX2-5", "description": "" }, { "id": "MONDO:0013749", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013749", "name": "ventricular septal defect 3", "description": "" }, { "id": "MONDO:0013749", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013749", "name": "ventricular septal defect type 3", "description": "" }, { "id": "MONDO:0013749", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013749", "name": "VSD3", "description": "" }, { "id": "MIM:614429", "resource": "MIM", "url": "https://www.omim.org/entry/614429", "name": "Ventricular septal defect 1", "description": "Ventricular septal defect 1" }, { "id": "MIM:614431", "resource": "MIM", "url": "https://www.omim.org/entry/614431", "name": "Ventricular septal defect 2", "description": "Ventricular septal defect 2" }, { "id": "MIM:614432", "resource": "MIM", "url": "https://www.omim.org/entry/614432", "name": "Ventricular septal defect 3", "description": "Ventricular septal defect 3" } ], "unlinked_id_list": [], "evidence": [ { "id": "1657", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1657" } ] }, { "disease_id": "DOID:1682", "recommended_name": { "id": "DOID:1682", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1682", "name": "congenital heart disease", "description": "A physical disorder that is characterized by problems with the heart's structure that are present at birth." }, "synonyms": [ { "id": "DOID:1682", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1682", "name": "Congenital Heart Defects", "description": "" }, { "id": "DOID:1682", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1682", "name": "Congenital anomaly of heart", "description": "" }, { "id": "DOID:1682", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1682", "name": "Heart Malformation", "description": "" }, { "id": "DOID:1682", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1682", "name": "congenital heart defect", "description": "" }, { "id": "DOID:1682", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1682", "name": "heart defect", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "1682", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1682" } ] }, { "disease_id": "DOID:1882", "recommended_name": { "id": "DOID:1882", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1882", "name": "atrial heart septal defect", "description": "A heart septal defect located_in in the septum that separates the two atria of the heart." }, "synonyms": [ { "id": "DOID:1882", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1882", "name": "atrial septal defect", "description": "" }, { "id": "DOID:1882", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1882", "name": "atrioseptal defect", "description": "" }, { "id": "DOID:1882", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1882", "name": "auricular septal defect", "description": "" }, { "id": "DOID:1882", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1882", "name": "congenital atrial septal defect", "description": "" }, { "id": "DOID:1882", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1882", "name": "interatrial septal defect", "description": "" }, { "id": "DOID:1882", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1882", "name": "interauricular septal defect", "description": "" }, { "id": "MONDO:0007172", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007172", "name": "atrial septal defect 1", "description": "An atrial heart septal defect type 1 associated with variation in the region 5p." }, { "id": "MONDO:0007172", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007172", "name": "ASD1", "description": "" }, { "id": "MONDO:0007172", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007172", "name": "atrial heart septal defect type 1", "description": "" }, { "id": "MONDO:0007172", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007172", "name": "atrial septal defect 1", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "1882", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1882" } ] }, { "disease_id": "DOID:6419", "recommended_name": { "id": "DOID:6419", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:6419", "name": "tetralogy of Fallot", "description": "" }, "synonyms": [ { "id": "DOID:6419", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:6419", "name": "Ventricular septal defect with pulmonary stenosis or atresia, dextraposition of aorta, and hypertrophy of right ventricle", "description": "" }, { "id": "MONDO:0008542", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008542", "name": "tetralogy of fallot", "description": "Tetralogy of Fallot is a congenital cardiac malformation that consists of an interventricular communication, also known as a ventricular septal defect, obstruction of the right ventricular outflow tract, override of the ventricular septum by the aortic root, and right ventricular hypertrophy." }, { "id": "MONDO:0008542", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008542", "name": "tetralogy of fallot", "description": "" }, { "id": "MONDO:0008542", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008542", "name": "ventricular septal defect with pulmonary stenosis or atresia, dextraposition of aorta, and hypertrophy of right ventricle", "description": "" }, { "id": "MONDO:0008542", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008542", "name": "Fallot tetralogy", "description": "" }, { "id": "MONDO:0008542", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008542", "name": "TOF", "description": "" }, { "id": "MIM:187500", "resource": "MIM", "url": "https://www.omim.org/entry/187500", "name": "Tetralogy of Fallot", "description": "Tetralogy of Fallot" } ], "unlinked_id_list": [], "evidence": [ { "id": "6419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6419" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VMR2", "url": "https://www.uniprot.org/uniprotkb/Q9VMR2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "mid", "url": "https://www.uniprot.org/uniprotkb/Q9VMR2", "locus": { "chromosome": "2L", "start_pos": 5467610, "end_pos": 5461639, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0261963", "url": "https://www.ensemblgenomes.org/id/FBgn0261963" } ] } } ], "crossref": [ { "id": "FB:FBgn0261963", "url": "https://alliancegenome.org/gene/FB:FBgn0261963", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0261963", "url": "https://bgee.org/?page=gene&gene_id=FBgn0261963", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd20193", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20193", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0261963", "url": "https://flybase.org/reports/FBgn0261963", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "33770", "url": "https://www.ncbi.nlm.nih.gov/gene/33770", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VMR2", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VMR2*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR001699", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001699", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008967", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008967", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036960", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036960", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046360", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046360", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG6634", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG6634", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DMRPRQF", "url": "https://omabrowser.org/oma/group/DMRPRQF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VMR2", "url": "https://www.orthodb.org/?gene=Q9VMR2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11267", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11267", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11267:SF190", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11267:SF190", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00907", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00907", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001260096", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260096", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VMR2", "url": "https://www.uniprot.org/uniprotkb/Q9VMR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VMR2-1", "url": "https://www.uniprot.org/uniprotkb/Q9VMR2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLVGSHPYLCNGVPAAPAAPNASGQTTTTASKSAAGSATDFSIAAIMAREDASSRESSIRSASPISVEDEVDVDVVDCSDAEEPPTKARRLNHHQHHQHHQHHHNNNNNNNNNNVAHKSRNSGGAVAQTASAESQLNTSSTSSQGRCSTPPQSPGTEDSEERLTPEPVQKAPKIVGSCNCDDLKPVQCHLETKELWDRFHDLGTEMIITKTGRRMFPTVRVSFSGPLRQIQPADRYAVLMDIIPMDSKRYRYAYHRSAWLVAGKADPAPPARLYAHPDSPFSCEALRKQVISFEKVKLTNNEMDKNGQIVLNSMHRYQPRIHLVRLSHGQSIPSNPKELQDLDHKTYVFPETVFTAVTAYQNQLITKLKIDSNPFAKGFRDSSRLTDFDRDPMEALLLEQQLRSPLRLFPDPLMQQFAAQGDPSSMALFEKARQHLQMFGGNSPYAQLMMPQMYQAAAAAAGPPPPPPGLGAFHMFQQQWPQLTAGFLASANQQAAAAQAAAQAQAQAQAAAAAMAANRTPPPPPTASTPSSTSSGSPSPDMRPRQYQRFSPYQLPGGQGPPSSAAGSPPAVNASRSPAH", "length": 580, "header": "tr|Q9VMR2-1|Q9VMR2_DROME Isoform 1 of Midline, isoform A OS=Drosophila melanogaster OX=7227 GN=mid PE=4 SV=1 CANONICAL=Q9VMR2-1" }, "isoforms": [ { "isoform_ac": "Q9VMR2-1", "url": "https://www.uniprot.org/uniprotkb/Q9VMR2/entry#Q9VMR2-1", "sequence": { "sequence": "MLVGSHPYLCNGVPAAPAAPNASGQTTTTASKSAAGSATDFSIAAIMAREDASSRESSIRSASPISVEDEVDVDVVDCSDAEEPPTKARRLNHHQHHQHHQHHHNNNNNNNNNNVAHKSRNSGGAVAQTASAESQLNTSSTSSQGRCSTPPQSPGTEDSEERLTPEPVQKAPKIVGSCNCDDLKPVQCHLETKELWDRFHDLGTEMIITKTGRRMFPTVRVSFSGPLRQIQPADRYAVLMDIIPMDSKRYRYAYHRSAWLVAGKADPAPPARLYAHPDSPFSCEALRKQVISFEKVKLTNNEMDKNGQIVLNSMHRYQPRIHLVRLSHGQSIPSNPKELQDLDHKTYVFPETVFTAVTAYQNQLITKLKIDSNPFAKGFRDSSRLTDFDRDPMEALLLEQQLRSPLRLFPDPLMQQFAAQGDPSSMALFEKARQHLQMFGGNSPYAQLMMPQMYQAAAAAAGPPPPPPGLGAFHMFQQQWPQLTAGFLASANQQAAAAQAAAQAQAQAQAAAAAMAANRTPPPPPTASTPSSTSSGSPSPDMRPRQYQRFSPYQLPGGQGPPSSAAGSPPAVNASRSPAH", "length": 580, "header": "tr|Q9VMR2-1|Q9VMR2_DROME Isoform 1 of Midline, isoform A OS=Drosophila melanogaster OX=7227 GN=mid PE=4 SV=1 CANONICAL=Q9VMR2-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 526, "start_aa": "Thr", "end_pos": 526, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr526", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 529, "start_aa": "Thr", "end_pos": 529, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr529", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VMR2", "url": "https://www.uniprot.org/uniprotkb/Q9VMR2" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VMR2", "url": "https://www.uniprot.org/uniprotkb/Q9VMR2" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMR2", "url": "https://www.uniprot.org/uniprotkb/Q9VMR2" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMR2", "url": "https://www.uniprot.org/uniprotkb/Q9VMR2" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VMR2", "url": "https://www.uniprot.org/uniprotkb/Q9VMR2" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VMR2", "url": "https://www.uniprot.org/uniprotkb/Q9VMR2" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VMR2", "url": "https://www.uniprot.org/uniprotkb/Q9VMR2" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMR2", "url": "https://www.uniprot.org/uniprotkb/Q9VMR2" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMR2", "url": "https://www.uniprot.org/uniprotkb/Q9VMR2" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VMR2", "url": "https://www.uniprot.org/uniprotkb/Q9VMR2" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VMR2", "url": "https://www.uniprot.org/uniprotkb/Q9VMR2" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], 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"url": "https://www.uniprot.org/uniprotkb/Q9VMR2" } ], "pmid": "" }, { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { "database": "UniProtKB", "id": "Q9VMR2", "url": "https://www.uniprot.org/uniprotkb/Q9VMR2" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "Q9VMR2", "url": "https://www.uniprot.org/uniprotkb/Q9VMR2" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "Q9VMR2", "url": "https://www.uniprot.org/uniprotkb/Q9VMR2" } ], "pmid": "" }, { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "Q9VMR2", "url": "https://www.uniprot.org/uniprotkb/Q9VMR2" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "Q9VMR2", "url": "https://www.uniprot.org/uniprotkb/Q9VMR2" } ], "pmid": "" }, { "name": "neuron fate specification", "id": "GO:0048665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048665", "evidence": [ { "database": "UniProtKB", "id": "Q9VMR2", "url": "https://www.uniprot.org/uniprotkb/Q9VMR2" } ], "pmid": "" }, { "name": "embryonic heart tube development", "id": "GO:0035050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035050", "evidence": [ { "database": "UniProtKB", "id": "Q9VMR2", "url": "https://www.uniprot.org/uniprotkb/Q9VMR2" } ], "pmid": "" }, { "name": "fasciculation of motor neuron axon", "id": "GO:0097156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097156", "evidence": [ { "database": "UniProtKB", "id": "Q9VMR2", "url": "https://www.uniprot.org/uniprotkb/Q9VMR2" } ], "pmid": "" }, { "name": "gonad development", "id": "GO:0008406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008406", "evidence": [ { "database": "UniProtKB", "id": "Q9VMR2", "url": "https://www.uniprot.org/uniprotkb/Q9VMR2" } ], "pmid": "" }, { "name": "regulation of nervous system development", "id": "GO:0051960", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051960", "evidence": [ { "database": "UniProtKB", "id": "Q9VMR2", "url": "https://www.uniprot.org/uniprotkb/Q9VMR2" } ], "pmid": "" }, { "name": "regulation of cell fate specification", "id": "GO:0042659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042659", "evidence": [ { "database": "UniProtKB", "id": "Q9VMR2", "url": "https://www.uniprot.org/uniprotkb/Q9VMR2" } ], "pmid": "" }, { "name": "heart process", "id": "GO:0003015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003015", "evidence": [ { "database": "UniProtKB", "id": "Q9VMR2", "url": "https://www.uniprot.org/uniprotkb/Q9VMR2" } ], "pmid": "" }, { "name": "neuroblast fate specification", "id": "GO:0014018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014018", "evidence": [ { "database": "UniProtKB", "id": "Q9VMR2", "url": "https://www.uniprot.org/uniprotkb/Q9VMR2" } ], "pmid": "" }, { "name": "neuroblast development", "id": "GO:0014019", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014019", "evidence": [ { "database": "UniProtKB", "id": "Q9VMR2", "url": "https://www.uniprot.org/uniprotkb/Q9VMR2" } ], "pmid": "" }, { "name": "chorion-containing eggshell pattern formation", "id": "GO:0030381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030381", "evidence": [ { "database": "UniProtKB", "id": "Q9VMR2", "url": "https://www.uniprot.org/uniprotkb/Q9VMR2" } ], "pmid": "" }, { "name": "leg disc pattern formation", "id": "GO:0035223", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035223", "evidence": [ { "database": "UniProtKB", "id": "Q9VMR2", "url": "https://www.uniprot.org/uniprotkb/Q9VMR2" } ], "pmid": "" }, { "name": "cardioblast cell fate commitment", "id": "GO:0042684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042684", "evidence": [ { "database": "UniProtKB", "id": "Q9VMR2", "url": "https://www.uniprot.org/uniprotkb/Q9VMR2" } ], "pmid": "" }, { "name": "regulation of cardioblast differentiation", "id": "GO:0051890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051890", "evidence": [ { "database": "UniProtKB", "id": "Q9VMR2", "url": "https://www.uniprot.org/uniprotkb/Q9VMR2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VMR2", "url": "https://www.uniprot.org/uniprotkb/Q9VMR2" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": 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"sequence": "MGIPDIRLLVTLDFEVYGHVQGLNLTKDTRDRCTKAGITGWVKNSKQGTIVGKMQGPKEEVDKMITWLSTEGSPGCQIDRCEVRNQGNLSRLDYKDFAIRF", "length": 101, "header": "tr|Q9VMR9-1|Q9VMR9_DROME Isoform 1 of acylphosphatase OS=Drosophila melanogaster OX=7227 GN=BcDNA:RH62365 PE=3 SV=1 CANONICAL=Q9VMR9-1" }, "isoforms": [ { "isoform_ac": "Q9VMR9-1", "url": "https://www.uniprot.org/uniprotkb/Q9VMR9/entry#Q9VMR9-1", "sequence": { "sequence": "MGIPDIRLLVTLDFEVYGHVQGLNLTKDTRDRCTKAGITGWVKNSKQGTIVGKMQGPKEEVDKMITWLSTEGSPGCQIDRCEVRNQGNLSRLDYKDFAIRF", "length": 101, "header": "tr|Q9VMR9-1|Q9VMR9_DROME Isoform 1 of acylphosphatase OS=Drosophila melanogaster OX=7227 GN=BcDNA:RH62365 PE=3 SV=1 CANONICAL=Q9VMR9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VMR9", "url": "https://www.uniprot.org/uniprotkb/Q9VMR9" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VMR9", "url": "https://www.uniprot.org/uniprotkb/Q9VMR9" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMR9", "url": "https://www.uniprot.org/uniprotkb/Q9VMR9" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMR9", "url": "https://www.uniprot.org/uniprotkb/Q9VMR9" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VMR9", "url": "https://www.uniprot.org/uniprotkb/Q9VMR9" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VMR9", "url": "https://www.uniprot.org/uniprotkb/Q9VMR9" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VMR9", "url": "https://www.uniprot.org/uniprotkb/Q9VMR9" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMR9", "url": "https://www.uniprot.org/uniprotkb/Q9VMR9" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMR9", "url": "https://www.uniprot.org/uniprotkb/Q9VMR9" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VMR9", "url": "https://www.uniprot.org/uniprotkb/Q9VMR9" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VMR9", "url": "https://www.uniprot.org/uniprotkb/Q9VMR9" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG14022", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG14022", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P14621-1", "protein_name": "Acylphosphatase-2", "gene_name": "ACYP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSTAQSLKSVDYEVFGRVQGVCFRMYTEDEARKIGVVGWVKNTSKGTVTGQVQGPEDKVNSMKSWLSKVGSPSSRIDRTNFSNEKTISKLEYSNFSIRY", "length": 99 }, "evidence": [ { "id": "HGNC:180", "url": "https://alliancegenome.org/gene/HGNC:180#orthology", "database": "AGR" }, { "id": "MGI:1922822", "url": "https://alliancegenome.org/gene/MGI:1922822#orthology", "database": "AGR" }, { "id": "FB:FBgn0031700", "url": "https://alliancegenome.org/gene/FB:FBgn0031700#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P35745-1", "protein_name": "Acylphosphatase-2", "gene_name": "Acyp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEPLKSVDYEVFGTVQGVCFRMYTEGEAKKRGLVGWVKNTSKGTVTGQVQGPEEKVNSMKSWLSKVGSPSSRIDRADFSNEKTISKLEYSNFSIRY", "length": 97 }, "evidence": [ { "id": "HGNC:180", "url": "https://alliancegenome.org/gene/HGNC:180#orthology", "database": "AGR" }, { "id": "MGI:1922822", "url": "https://alliancegenome.org/gene/MGI:1922822#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P56375-1", "protein_name": "Acylphosphatase-2", "gene_name": "Acyp2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLGRRLAAMTELLKSVDYEVFGTVQGVCFRMYTEGEAKKRGLVGWVKNTSKGTVTGQVQGPEEKVDAMKSWLSKVGSPSSRIDRADFSNEKTISKLEYSDFSIRY", "length": 106 }, "evidence": [ { "id": "HGNC:180", "url": "https://alliancegenome.org/gene/HGNC:180#orthology", "database": "AGR" }, { "id": "MGI:1922822", "url": "https://alliancegenome.org/gene/MGI:1922822#orthology", "database": "AGR" }, { "id": "FB:FBgn0031700", "url": "https://alliancegenome.org/gene/FB:FBgn0031700#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VHX3-1", "protein_name": "acylphosphatase", "gene_name": "Dmel\\CG11052", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTSQETQTEGERRRVTLPSSTPDKGTPSKKGSEEPNRISNTEFQKRVTSDRSDEPVFSCQFEVFGIVQGVSFRMYTLRRAQKLGVRGWCKNTNENTVKGEIQAHRHSFESMRLWLKHTGSPTSRIDKCIFSETTELSEFTFTNFSIVVD", "length": 149 }, "evidence": [ { "id": "MGI:1922822", "url": "https://alliancegenome.org/gene/MGI:1922822#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "acylphosphatase activity", "id": "GO:0003998", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003998", "evidence": [ { "database": "UniProtKB", "id": "Q9VMR9", "url": "https://www.uniprot.org/uniprotkb/Q9VMR9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 24, "end_pos": 26, "annotation": "n_glycosylation_sequon" }, { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "14965", "name": "", "equation": "an acyl phosphate + H2O = a carboxylate + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P56544-1", "Q9VF36-1", "Q9VHX3-1", "Q9VMR9-1" ], "evidence": [ { "id": "14965", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/14965" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "P56544", "gene_name": "Acyp", "activity": [ { "ec_number": "3.6.1.7", "activity": "an acyl phosphate + H2O = a carboxylate + phosphate + H(+).", "evidence": [ { "id": "P56544", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P56544" } ] }, { "ec_number": "3.6.1.7", 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"Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-9939291", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9939291", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001260094", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260094", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VMS3", "url": "https://www.uniprot.org/uniprotkb/Q9VMS3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VMS3-1", "url": "https://www.uniprot.org/uniprotkb/Q9VMS3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLIRLRYGRRLQTYLKIGACVLVGLCYFAFLFRESLNAYEHRERATAAELEAESEPSKQQLKLKRQQLQRQRILAKQQEQGKGIAGGNASAGSSSSQAAAPPPPPPATTLNPVYEYSEELHSRTERELQRRSEHLAAVCDRYKLQEKYPPNPWEFFVSPGHNNLVWCNVFKAASSTWMYYFNILAGYDVKYLQRTETQPLELARKRFPRPELGELMELLPSALSFLFVRDPFERILSAYRNKLEGNKNTFYKALGNKIVHRYRKRNLGGPWPRCGPTFEEFVRFLIAEHAAGKRFDEHWAPVYSFCTPCSVNFTIIGKTETFQRDSEFIIRQAGLESLLLGLGKLPQRKQRKIGNQARSGVKSEALVERYFADLDRSTLDQLLKIYRIDFELFDYDYRRYYDMVHPWSLEQSTAASGGPAVASTSTTPSISSGLAGQSTQGQAT", "length": 444, "header": "tr|Q9VMS3-1|Q9VMS3_DROME Isoform 1 of Carbohydrate sulfotransferase OS=Drosophila melanogaster OX=7227 GN=d4ST1 PE=3 SV=1 CANONICAL=Q9VMS3-1" }, "isoforms": [ { "isoform_ac": "Q9VMS3-1", "url": "https://www.uniprot.org/uniprotkb/Q9VMS3/entry#Q9VMS3-1", "sequence": { "sequence": 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Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VMS3", "url": "https://www.uniprot.org/uniprotkb/Q9VMS3" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VMS3", "url": "https://www.uniprot.org/uniprotkb/Q9VMS3" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMS3", "url": "https://www.uniprot.org/uniprotkb/Q9VMS3" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMS3", "url": "https://www.uniprot.org/uniprotkb/Q9VMS3" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VMS3", "url": "https://www.uniprot.org/uniprotkb/Q9VMS3" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VMS3", "url": "https://www.uniprot.org/uniprotkb/Q9VMS3" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VMS3", "url": "https://www.uniprot.org/uniprotkb/Q9VMS3" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMS3", "url": "https://www.uniprot.org/uniprotkb/Q9VMS3" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMS3", "url": "https://www.uniprot.org/uniprotkb/Q9VMS3" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"url": "https://www.ncbi.nlm.nih.gov/protein/NP_608884" }, { "id": "Q9VMX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMX4" } ] }, { "name": "l(2)SH2 1783", "type": "synonym", "evidence": [ { "id": "NP_608884", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608884" }, { "id": "Q9VMX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMX4" } ] }, { "name": "scox", "type": "synonym", "evidence": [ { "id": "NP_608884", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608884" }, { "id": "Q9VMX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMX4" } ] } ], "protein_names": [ { "name": "CG8885-PA", "type": "synonym", "evidence": [ { "id": "NP_608884", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608884" } ] }, { "name": "SCO1 protein homolog", "type": "synonym", "evidence": [ { "id": "NP_608884", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608884" } ] }, { "name": "Scox-PA", "type": "synonym", "evidence": [ { "id": "NP_608884", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608884" } ] }, { "name": "Synthesis of cytochrome c oxidase", "type": "synonym", "evidence": [ { "id": "Q9VMX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMX4/entry#names_and_taxonomy" } ] }, { "name": "lethal (2) SH1783", "type": "synonym", "evidence": [ { "id": "NP_608884", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608884" } ] }, { "name": "synthesis of cytochrome c oxidase X", "type": "synonym", "evidence": [ { "id": "NP_608884", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608884" } ] }, { "name": "synthesis of cytochrome c oxidase", "type": "synonym", "evidence": [ { "id": "NP_608884", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608884" } ] } ], "function": [ { "annotation": "Copper metallochaperone essential for the synthesis and maturation of cytochrome c oxidase subunit II (MT-CO2/COX2).", "evidence": [ { "database": "UniProtKB", "id": "Q9VMX4", "url": "https://www.uniprot.org/uniprotkb/Q9VMX4#function" }, { "database": "UniProtKB", "id": "PIRNR037736", "url": "https://www.uniprot.org/uniprotkb/PIRNR037736#function" } ] } ], "disease": [ { "disease_id": "DOID:0050700", "recommended_name": { "id": "DOID:0050700", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050700", "name": "cardiomyopathy", "description": "A heart disease and a myopathy that is characterized by deterioration of the function of the heart muscle." }, "synonyms": [ { "id": "DOID:0050700", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050700", "name": "Cardiomyopathies", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "0050700", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050700" } ] }, { "disease_id": "DOID:0070493", "recommended_name": { "id": "DOID:0070493", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070493", "name": "mitochondrial complex IV deficiency nuclear type 4", "description": "A COX deficiency, benign infantile mitochondrial myopathy that has_material_basis_in homozygous or compound heterozygous mutation in the SCO1 gene on chromosome 17p13.1." }, "synonyms": [ { "id": "DOID:0070493", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070493", "name": "MC4DN4", "description": "" }, { "id": "MONDO:0033636", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0033636", "name": "mitochondrial complex IV deficiency, nuclear type 4", "description": "Any mitochondrial complex IV deficiency in which the cause of the disease is a mutation in the SCO1 gene." }, { "id": "MONDO:0033636", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0033636", "name": "MC4DN4", "description": "" }, { "id": "MONDO:0033636", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0033636", "name": "mitochondrial complex IV deficiency, nuclear type 4", "description": "" }, { "id": "MIM:619048", "resource": "MIM", "url": "https://www.omim.org/entry/619048", "name": "Mitochondrial complex IV deficiency, nuclear type 4", "description": "Mitochondrial complex IV deficiency, nuclear type 4" } ], "unlinked_id_list": [], "evidence": [ { "id": "0070493", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070493" } ] }, { "disease_id": "DOID:0080357", "recommended_name": { "id": "DOID:0080357", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080357", "name": "mitochondrial complex IV deficiency nuclear type 2", "description": "A COX deficiency, infantile mitochondrial myopathy that has_material_basis_in compound heterozygous 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"MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011451", "name": "cardioencephalomyopathy, fatal infantile, due to cytochrome C oxidase deficiency type 1", "description": "" }, { "id": "MONDO:0011451", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011451", "name": "cardioencephalomyopathy, fatal infantile, due to cytochrome c oxidase deficiency 1", "description": "" }, { "id": "MONDO:0011451", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011451", "name": "fatal infantile encephalocardiomyopathy caused by mutation in SCO2", "description": "" }, { "id": "MONDO:0011451", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011451", "name": "mitochondrial complex IV deficiency, nuclear type 2", "description": "" }, { "id": "MONDO:0011451", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011451", "name": "CEMCOX1", "description": "" }, { "id": "MIM:604377", "resource": "MIM", "url": "https://www.omim.org/entry/604377", "name": "Mitochondrial complex IV deficiency, nuclear type 2", "description": "Mitochondrial complex IV deficiency, nuclear type 2" } ], "unlinked_id_list": [], "evidence": [ { "id": "0080357", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080357" } ] }, { "disease_id": "DOID:11830", "recommended_name": { "id": "DOID:11830", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11830", "name": "myopia", "description": "A refractive error characterized by the inability to see farther objects clearly." }, "synonyms": [ { "id": "DOID:11830", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11830", "name": "near vision", "description": "" }, { "id": "DOID:11830", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11830", "name": "near-sightedness", "description": "" }, { "id": "DOID:11830", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11830", "name": "short-sightedness", "description": "" }, { "id": "MONDO:0008053", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008053", "name": "myopia 2, autosomal dominant", "description": "" }, { "id": "MONDO:0008053", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008053", "name": "MYP2", "description": "" }, { "id": "MONDO:0008053", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008053", "name": "myopia 2, autosomal dominant", "description": "" }, { "id": "MONDO:0009713", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009713", "name": "myopia 18, autosomal recessive", "description": "" }, { "id": "MONDO:0009713", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009713", "name": "MYP18", "description": "" }, { "id": "MONDO:0009713", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009713", "name": "myopia 18, autosomal recessive", "description": "" }, { "id": "MONDO:0010377", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010377", "name": "myopia 13, X-linked", "description": "" }, { "id": "MONDO:0010377", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010377", "name": "MYP13", "description": "" }, { "id": "MONDO:0010377", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010377", "name": "myopia 13", "description": "" }, { "id": "MONDO:0010377", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010377", "name": "myopia 13, X-linked", "description": "" }, { "id": "MONDO:0010685", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010685", "name": "myopia 1, X-linked", "description": "" }, { "id": "MONDO:0010685", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010685", "name": "MYP1", "description": "" }, { "id": "MONDO:0010685", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010685", "name": "myopia 1, X-linked", "description": "" }, { "id": "MONDO:0010685", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010685", "name": "myopia-1, X-linked recessive", "description": "" }, { "id": "MONDO:0011300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011300", "name": "myopia 3, autosomal dominant", "description": "" }, { "id": "MONDO:0011300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011300", "name": "MYP3", "description": "" }, { "id": "MONDO:0011300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011300", "name": "myopia 3, autosomal dominant", "description": "" }, { "id": "MONDO:0011300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011300", "name": "myopia-3", "description": "" }, { "id": "MONDO:0012021", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012021", "name": "myopia 17, autosomal dominant", "description": "" }, { "id": "MONDO:0012021", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012021", "name": "MYP17", "description": "" }, { "id": "MONDO:0012021", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012021", "name": "myopia 17, autosomal dominant", "description": "" }, { "id": "MONDO:0012021", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012021", "name": "myopia 4", "description": "" }, { "id": "MONDO:0012045", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012045", "name": "myopia 5, autosomal dominant", "description": "" }, { "id": "MONDO:0012045", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012045", "name": "MYP5", "description": "" }, { "id": "MONDO:0012045", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012045", "name": "myopia 5, autosomal dominant", "description": "" }, { "id": "MONDO:0012154", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012154", "name": "myopia 6", "description": "Any myopia in which the cause of the disease is a mutation in the SCO2 gene." }, { "id": "MONDO:0012154", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012154", "name": "SCO2 myopia (disease)", "description": "" }, { "id": "MONDO:0012154", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012154", "name": "myopia (disease) caused by mutation in SCO2", "description": "" }, { "id": "MONDO:0012154", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012154", "name": "myopia 6", "description": "" }, { "id": "MONDO:0012154", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012154", "name": "myopia type 6", "description": "" }, { "id": "MONDO:0012154", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012154", "name": "MYP6", "description": "" }, { "id": "MONDO:0012154", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012154", "name": "myopia, susceptibility to", "description": "" }, { "id": "MONDO:0012227", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012227", "name": "myopia 7", "description": "" }, { "id": "MONDO:0012227", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012227", "name": "MYP7", "description": "" }, { "id": "MONDO:0012227", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012227", "name": "myopia 7", "description": "" }, { "id": "MONDO:0012228", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012228", "name": "myopia 8", "description": "" }, { "id": "MONDO:0012228", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012228", "name": "MYP8", "description": "" }, { "id": "MONDO:0012228", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012228", "name": "myopia 8", "description": "" }, { "id": "MONDO:0012229", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012229", "name": "myopia 9", "description": "" }, { "id": "MONDO:0012229", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012229", "name": "MYP9", "description": "" }, { "id": "MONDO:0012229", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012229", "name": "myopia 9", "description": "" }, { "id": "MONDO:0012230", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012230", "name": "myopia 10", "description": "" }, { "id": "MONDO:0012230", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012230", "name": "MYP10", "description": "" }, { "id": "MONDO:0012230", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012230", "name": "myopia 10", "description": "" }, { "id": "MONDO:0012388", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012388", "name": "myopia 11, autosomal dominant", "description": "" }, { "id": "MONDO:0012388", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012388", "name": "MYP11", "description": "" }, { "id": "MONDO:0012388", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012388", "name": "myopia 11", "description": "" }, { "id": "MONDO:0012388", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012388", "name": "myopia 11, autosomal dominant", "description": "" }, { "id": "MONDO:0012389", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012389", "name": "myopia 12, autosomal dominant", "description": "" }, { "id": "MONDO:0012389", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012389", "name": "MYP12", "description": "" }, { "id": "MONDO:0012389", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012389", "name": "myopia 12", "description": "" }, { "id": "MONDO:0012389", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012389", "name": "myopia 12, autosomal dominant", "description": "" }, { "id": "MONDO:0012469", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012469", "name": "myopia 14", "description": "" }, { "id": "MONDO:0012469", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012469", "name": "MYP14", "description": "" }, { "id": "MONDO:0012469", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012469", "name": "myopia 14", "description": "" }, { "id": "MONDO:0012932", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012932", "name": "myopia 16, autosomal dominant", "description": "" }, { "id": "MONDO:0012932", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012932", "name": "MYP16", "description": "" }, { "id": "MONDO:0012932", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012932", "name": "myopia 16", "description": "" }, { "id": "MONDO:0012932", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012932", "name": "myopia 16, autosomal dominant", "description": "" }, { "id": "MONDO:0012995", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012995", "name": "myopia 15, autosomal dominant", "description": "" }, { "id": "MONDO:0012995", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012995", "name": "MYP15", "description": "" }, { "id": "MONDO:0012995", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012995", "name": "myopia 15, autosomal dominant", "description": "" }, { "id": "MONDO:0013508", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013508", "name": "myopia 19, autosomal dominant", "description": "" }, { "id": "MONDO:0013508", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013508", "name": "MYP19", "description": "" }, { "id": "MONDO:0013508", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013508", "name": "myopia 19, autosomal dominant", "description": "" }, { "id": "MONDO:0013603", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013603", "name": "myopia 20, autosomal dominant", "description": "" }, { "id": "MONDO:0013603", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013603", "name": "MYP20", "description": "" }, { "id": "MONDO:0013603", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013603", "name": "myopia 20, autosomal dominant", "description": "" }, { "id": "MONDO:0013604", "resource": 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"name": "myopia 22, autosomal dominant", "description": "" }, { "id": "MONDO:0014177", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014177", "name": "myopia 22, autosomal dominant", "description": "" }, { "id": "MONDO:0014177", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014177", "name": "MYP22", "description": "" }, { "id": "MONDO:0014183", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014183", "name": "myopia 23, autosomal recessive", "description": "" }, { "id": "MONDO:0014183", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014183", "name": "myopia 23, autosomal recessive", "description": "" }, { "id": "MONDO:0014183", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014183", "name": "MYP23", "description": "" }, { "id": "MONDO:0014411", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014411", "name": "myopia 24, autosomal dominant", "description": "" }, { "id": "MONDO:0014411", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014411", "name": "myopia 24, autosomal dominant", "description": "" }, { "id": "MONDO:0014411", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014411", "name": "MYP24", "description": "" }, { "id": "MIM:608908", "resource": "MIM", "url": "https://www.omim.org/entry/608908", "name": "Myopia 6", "description": "Myopia 6" }, { "id": "MIM:614167", "resource": "MIM", "url": "https://www.omim.org/entry/614167", "name": "Myopia 21, autosomal dominant", "description": "Myopia 21, autosomal dominant" }, { "id": "MIM:615420", "resource": "MIM", "url": "https://www.omim.org/entry/615420", "name": "Myopia 22, autosomal dominant", "description": "Myopia 22, autosomal dominant" }, { "id": "MIM:615431", "resource": "MIM", "url": "https://www.omim.org/entry/615431", "name": "Myopia 23, autosomal recessive", "description": "Myopia 23, autosomal recessive" }, { "id": "MIM:615946", "resource": "MIM", "url": "https://www.omim.org/entry/615946", "name": "Myopia 24, autosomal dominant", "description": "Myopia 24, autosomal dominant" } ], "unlinked_id_list": [], "evidence": [ { "id": "11830", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11830" } ] }, { "disease_id": "DOID:11984", "recommended_name": { "id": "DOID:11984", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11984", "name": "hypertrophic cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by abnormal thickening (hypertrophy) of the heart without any obvious cause." }, "synonyms": [ { "id": "DOID:11984", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11984", "name": "hypertrophic obstructive cardiomyopathy", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "11984", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11984" } ] }, { "disease_id": "DOID:1289", "recommended_name": { "id": "DOID:1289", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons." }, "synonyms": [ { "id": "DOID:1289", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1289", "name": "degenerative disease", "description": "" } ], "unlinked_id_list": [ "DOID:0112328", "DOID:0050953", "DOID:0111828", "DOID:0050765", "DOID:681", "DOID:0112322" ], "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ] }, { "disease_id": "DOID:3762", "recommended_name": { "id": "DOID:3762", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3762", "name": "cytochrome-c oxidase deficiency disease", 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[ { "id": "3762", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3762" } ] }, { "disease_id": "DOID:409", "recommended_name": { "id": "DOID:409", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:409", "name": "liver disease", "description": "" }, "synonyms": [ { "id": "DOID:409", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:409", "name": "disorder of liver", "description": "" }, { "id": "DOID:409", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:409", "name": "hepatic disorder", "description": "" } ], "unlinked_id_list": [ "DOID:272" ], "evidence": [ { "id": "409", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:409" } ] }, { "disease_id": "DOID:700", "recommended_name": { "id": "DOID:700", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:700", "name": "mitochondrial metabolism disease", "description": "An inherited 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"DOID:0070438" ], "evidence": [ { "id": "8466", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8466" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VMX4", "url": "https://www.uniprot.org/uniprotkb/Q9VMX4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Scox", "url": "https://www.uniprot.org/uniprotkb/Q9VMX4", "locus": { "chromosome": "2L", "start_pos": 4967832, "end_pos": 4968935, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0262467", "url": "https://www.ensemblgenomes.org/id/FBgn0262467" } ] } } ], "crossref": [ { "id": "FB:FBgn0262467", "url": "https://alliancegenome.org/gene/FB:FBgn0262467", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0262467", "url": 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"https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG8885", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG8885", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MLYFRVE", "url": "https://omabrowser.org/oma/group/MLYFRVE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VMX4", "url": "https://www.orthodb.org/?gene=Q9VMX4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12151", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12151", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12151:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12151:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02630", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02630", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-9864848", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9864848", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_608884", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608884", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VMX4", "url": "https://www.uniprot.org/uniprotkb/Q9VMX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VMX4-1", "url": "https://www.uniprot.org/uniprotkb/Q9VMX4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRSLQRLVGSCRRWAQQPAIRHYAAPADSTKGKGPISWRSLAVIGALGAGGVGFMLYVKSEKDEARMKERQRQLGKAAIGGSWELVDSQGAVRKSEDFLGKWLLIYFGFTHCPDICPDELEKMAAVVDEVEKSPQTPAVQPIFITVDPERDSKEVVAKYVKEFSPKLLGLTGTVEQIRKVCKAFRVYFSAGPRDEDNDYIVDHTIIMYLVNPDGEFVDYYGQNRDKDQCVASILVNIAKWNSMNKKGWFS", "length": 251, "header": "tr|Q9VMX4-1|Q9VMX4_DROME Isoform 1 of Synthesis of cytochrome c oxidase OS=Drosophila melanogaster OX=7227 GN=Scox PE=1 SV=1 CANONICAL=Q9VMX4-1" }, "isoforms": [ { "isoform_ac": "Q9VMX4-1", "url": "https://www.uniprot.org/uniprotkb/Q9VMX4/entry#Q9VMX4-1", "sequence": { "sequence": "MSRSLQRLVGSCRRWAQQPAIRHYAAPADSTKGKGPISWRSLAVIGALGAGGVGFMLYVKSEKDEARMKERQRQLGKAAIGGSWELVDSQGAVRKSEDFLGKWLLIYFGFTHCPDICPDELEKMAAVVDEVEKSPQTPAVQPIFITVDPERDSKEVVAKYVKEFSPKLLGLTGTVEQIRKVCKAFRVYFSAGPRDEDNDYIVDHTIIMYLVNPDGEFVDYYGQNRDKDQCVASILVNIAKWNSMNKKGWFS", "length": 251, "header": "tr|Q9VMX4-1|Q9VMX4_DROME Isoform 1 of Synthesis of cytochrome c oxidase OS=Drosophila melanogaster OX=7227 GN=Scox PE=1 SV=1 CANONICAL=Q9VMX4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VMX4", "url": "https://www.uniprot.org/uniprotkb/Q9VMX4" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VMX4", "url": "https://www.uniprot.org/uniprotkb/Q9VMX4" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMX4", "url": "https://www.uniprot.org/uniprotkb/Q9VMX4" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMX4", "url": "https://www.uniprot.org/uniprotkb/Q9VMX4" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VMX4", "url": "https://www.uniprot.org/uniprotkb/Q9VMX4" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VMX4", "url": "https://www.uniprot.org/uniprotkb/Q9VMX4" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VMX4", "url": "https://www.uniprot.org/uniprotkb/Q9VMX4" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMX4", "url": "https://www.uniprot.org/uniprotkb/Q9VMX4" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMX4", "url": "https://www.uniprot.org/uniprotkb/Q9VMX4" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VMX4", "url": "https://www.uniprot.org/uniprotkb/Q9VMX4" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VMX4", "url": "https://www.uniprot.org/uniprotkb/Q9VMX4" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG8885", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG8885", "resource": "KEGG Pathway" }, { "id": "R-DME-9864848", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9864848", "resource": "Reactome", "description": "Complex IV assembly" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287ACH8-1", "protein_name": "Synthesis of cytochrome C oxidase 1", "gene_name": "SCO1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGLLLARGGVLRPPGCKLGCLFPHGLGVYSPGEGTARVLLARLCARPVETWRPSGLASRWLGSRPLSTERPPPPGSSGPELKGSRDPTRPSKPGPVSWKSLAITFAIGGALLAGMKYLKKEKTEKLEKERQRSIGKPLLGGPFSLTTHTGEPKTDKDYLGQWVLIYFGFTHCPDICPEELEKMIQVVDEIDSIPTLPNLTPLFITIDPERDTEEAIANYVKEFSPKLIGLTGTKEAIDQVARAFRVYYSPGPKDEDEDYIVDHTIIMYLIGPDGEFIDYFGQNKKNGEIAGSIAAHMRNHRKKS", "length": 305 }, "evidence": [ { "id": "Q9VMX4", "url": "https://omabrowser.org/oma/group/Q9VMX4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0ABK0LFJ4-1", "protein_name": "Synthesis of cytochrome C oxidase 1", "gene_name": "Sco1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALVRLAVVRSQCRQLWHLFPRGHGLRGMAERPRPEEARCSLGSRNFSARPPPPGAGPEPKGSQAGSHRPKLGPVSWKSLALTFAIGGSLLAGMKYFKKEKIEKLEKQRHRSIGKPLLGGPFSLTTHNGEPKTDKDFLGQWVLIYFGFTHCPDICPEELEKMIEVVEEIDSIPSLPNLTPLFITIDPERDTKEAIATYVKEFSPKLVGLTGTKEEIDGVARAYRVYYSPGPKDEDEDYIVDHTIIMYLIGPDGEFLDYFGQNKKKAEIAGSIAAHMRSHMRKR", "length": 284 }, "evidence": [ { "id": "MGI:106362", "url": "https://alliancegenome.org/gene/MGI:106362#orthology", "database": "AGR" }, { "id": "HGNC:10603", "url": "https://alliancegenome.org/gene/HGNC:10603#orthology", "database": "AGR" }, { "id": "FB:FBgn0262467", "url": "https://alliancegenome.org/gene/FB:FBgn0262467#orthology", "database": "AGR" }, { "id": "RGD:1559538", "url": "https://alliancegenome.org/gene/RGD:1559538#orthology", "database": "AGR" }, { "id": "SGD:S000000228", "url": "https://alliancegenome.org/gene/SGD:S000000228#orthology", "database": "AGR" }, { "id": "SGD:S000000241", "url": "https://alliancegenome.org/gene/SGD:S000000241#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A1A4J8-1", "protein_name": "Cytochrome c oxidase assembly factor SCO1", "gene_name": "SCO1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAGLLLAPGRIMRLPGSQLWRLFPRGFGVWGPGKETASVLLGRLCARPEEAWRASGLAACCLGSRPLSTAMPPPPGSSGPEWKGSGDPMRPSKPGPVSWKSLAVTFAIGGALLAGMKYFKKEKTEKLEKERHRSIGKPLLGGPFSLTTHTGEPKTDKDYLGQWVLIYFGFTHCPDICPEELEKMIQVVDEIDSIPTLPNLTPLFITIDPERDTKEAIANYVKEFSPKLIGLTGTKEEIDQVARAFRVYYSPGPKDEDEDYIVDHTIIMYLIGPDGEFLDYFGQNKKNAEIAGSIAAHMRTHRKKS", "length": 305 }, "evidence": [ { "id": "Q9VMX4", "url": "https://omabrowser.org/oma/group/Q9VMX4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E7FD19-1", "protein_name": "Protein SCO1 homolog, mitochondrial", "gene_name": "sco1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRGSDGHFRVADVLTVSTMSLAAVLGLKSVRCQMFRLVCGSKTCNGVLSLRSAEGRAARACAVRSHSNTSLWRCRTAPCVSVLHMRTLSTLPPPPSSSGDKPSSRKTGPVTWKSLAVTFALGGGLLLAMKYFKREKEELFEKERTKSIGKPALGGPFSLLDHNNKPSRSEDFLGRWLLIYFGFTHCPDICPDELEKMIEAVDEIDNIDTLPDVTPLLISIDPERDTPEALAAYVKDFSPKLIGLTGTTAQIEQVSRAYRVYYSQGPKDEDNDYIVDHTIIMYLVGPDGQFLEYYGQNKKSSEIASSIASYMRKHKYGK", "length": 318 }, "evidence": [ { "id": "MGI:106362", "url": "https://alliancegenome.org/gene/MGI:106362#orthology", "database": "AGR" }, { "id": "HGNC:10603", "url": "https://alliancegenome.org/gene/HGNC:10603#orthology", "database": "AGR" }, { "id": "Q9VMX4", "url": "https://omabrowser.org/oma/group/Q9VMX4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O43819-1", "protein_name": "Cytochrome c oxidase assembly factor SCO2", "gene_name": "SCO2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLLLTRSPTAWHRLSQLKPRVLPGTLGGQALHLRSWLLSRQGPAETGGQGQPQGPGLRTRLLITGLFGAGLGGAWLALRAEKERLQQQKRTEALRQAAVGQGDFHLLDHRGRARCKADFRGQWVLMYFGFTHCPDICPDELEKLVQVVRQLEAEPGLPPVQPVFITVDPERDDVEAMARYVQDFHPRLLGLTGSTKQVAQASHSYRVYYNAGPKDEDQDYIVDHSIAIYLLNPDGLFTDYYGRSRSAEQISDSVRRHMAAFRSVLS", "length": 266 }, "evidence": [ { "id": "MGI:3818630", "url": "https://alliancegenome.org/gene/MGI:3818630#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041210-173", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041210-173#orthology", "database": "AGR" }, { "id": "FB:FBgn0262467", "url": "https://alliancegenome.org/gene/FB:FBgn0262467#orthology", "database": "AGR" }, { "id": "HGNC:10604", "url": "https://alliancegenome.org/gene/HGNC:10604#orthology", "database": "AGR" }, { "id": "SGD:S000000241", "url": "https://alliancegenome.org/gene/SGD:S000000241#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O75880-1", "protein_name": "Cytochrome c oxidase assembly factor SCO1", "gene_name": "SCO1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAMLVLVPGRVMRPLGGQLWRFLPRGLEFWGPAEGTARVLLRQFCARQAEAWRASGRPGYCLGTRPLSTARPPPPWSQKGPGDSTRPSKPGPVSWKSLAITFAIGGALLAGMKHVKKEKAEKLEKERQRHIGKPLLGGPFSLTTHTGERKTDKDYLGQWLLIYFGFTHCPDVCPEELEKMIQVVDEIDSITTLPDLTPLFISIDPERDTKEAIANYVKEFSPKLVGLTGTREEVDQVARAYRVYYSPGPKDEDEDYIVDHTIIMYLIGPDGEFLDYFGQNKRKGEIAASIATHMRPYRKKS", "length": 301 }, "evidence": [ { "id": "MGI:106362", "url": "https://alliancegenome.org/gene/MGI:106362#orthology", "database": "AGR" }, { "id": "HGNC:10603", "url": "https://alliancegenome.org/gene/HGNC:10603#orthology", "database": "AGR" }, { "id": "FB:FBgn0262467", "url": "https://alliancegenome.org/gene/FB:FBgn0262467#orthology", "database": "AGR" }, { "id": "RGD:1559538", "url": "https://alliancegenome.org/gene/RGD:1559538#orthology", "database": "AGR" }, { "id": "SGD:S000000228", "url": "https://alliancegenome.org/gene/SGD:S000000228#orthology", "database": "AGR" }, { "id": "SGD:S000000241", "url": "https://alliancegenome.org/gene/SGD:S000000241#orthology", "database": "AGR" }, { "id": "Q9VMX4", "url": "https://omabrowser.org/oma/group/Q9VMX4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P23833-1", "protein_name": "Cytochrome c oxidase assembly factor SCO1", "gene_name": "SCO1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLKLSRSANLRLVQLPAARLSGNGAKLLTQRGFFTVTRLWQSNGKKPLSRVPVGGTPIKDNGKVREGSIEFSTGKAIALFLAVGGALSYFFNREKRRLETQKEAEANRGYGKPSLGGPFHLEDMYGNEFTEKNLLGKFSIIYFGFSNCPDICPDELDKLGLWLNTLSSKYGITLQPLFITCDPARDSPAVLKEYLSDFHPSILGLTGTFDEVKNACKKYRVYFSTPPNVKPGQDYLVDHSIFFYLMDPEGQFVDALGRNYDEKTGVDKIVEHVKSYVPAEQRAKQKEAWYSFLFK", "length": 295 }, "evidence": [ { "id": "MGI:106362", "url": "https://alliancegenome.org/gene/MGI:106362#orthology", "database": "AGR" }, { "id": "MGI:3818630", "url": "https://alliancegenome.org/gene/MGI:3818630#orthology", "database": "AGR" }, { "id": "HGNC:10603", "url": "https://alliancegenome.org/gene/HGNC:10603#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041210-173", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041210-173#orthology", "database": "AGR" }, { "id": "FB:FBgn0262467", "url": "https://alliancegenome.org/gene/FB:FBgn0262467#orthology", "database": "AGR" }, { "id": "RGD:1559538", "url": "https://alliancegenome.org/gene/RGD:1559538#orthology", "database": "AGR" }, { "id": "HGNC:10604", "url": "https://alliancegenome.org/gene/HGNC:10604#orthology", "database": "AGR" }, { "id": "SGD:S000000241", "url": "https://alliancegenome.org/gene/SGD:S000000241#orthology", "database": "AGR" }, { "id": "Q9VMX4", "url": "https://omabrowser.org/oma/group/Q9VMX4/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P38072-1", "protein_name": "Cytochrome c oxidase assembly factor SCO2", "gene_name": "SCO2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLNSSRKYACRSLFRQANVSIKGLFYNGGAYRRGFSTGCCLRSDNKESPSARQPLDRLQLGDEINEPEPIRTRFFQFSRWKATIALLLLSGGTYAYLSRKRRLLETEKEADANRAYGSVALGGPFNLTDFNGKPFTEENLKGKFSILYFGFSHCPDICPEELDRLTYWISELDDKDHIKIQPLFISCDPARDTPDVLKEYLSDFHPAIIGLTGTYDQVKSVCKKYKVYFSTPRDVKPNQDYLVDHSIFFYLIDPEGQFIDALGRNYDEQSGLEKIREQIQAYVPKEERERRSKKWYSFIFN", "length": 301 }, "evidence": [ { "id": "MGI:106362", "url": "https://alliancegenome.org/gene/MGI:106362#orthology", "database": "AGR" }, { "id": "MGI:3818630", "url": "https://alliancegenome.org/gene/MGI:3818630#orthology", "database": "AGR" }, { "id": "HGNC:10603", "url": "https://alliancegenome.org/gene/HGNC:10603#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041210-173", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041210-173#orthology", "database": "AGR" }, { "id": "FB:FBgn0262467", "url": "https://alliancegenome.org/gene/FB:FBgn0262467#orthology", "database": "AGR" }, { "id": "RGD:1559538", "url": "https://alliancegenome.org/gene/RGD:1559538#orthology", "database": "AGR" }, { "id": "SGD:S000000228", "url": "https://alliancegenome.org/gene/SGD:S000000228#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q5FVR2-1", "protein_name": "Thymidine phosphorylase", "gene_name": "Tymp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAPGTPPPLAPETAGADSGGGSGEHRQLPELIRLKRNGGHLSEADIRNFVHALMDGRAQDTQIGAMLMAIRLQGMDLEETSVLTQALAESGQQLEWPKAWHQQLVDKHSTGGVGDKVSLVLAPALAACGCKVPMISGRSLGHTGGTLDKLESIPGFSVTQSPEQMLQILEEVGCCIVGQSEKLVPADGILYAARDVTATVDSVPLITASILSKKAVEGLSTLVVDVKFGGAAVFPDQEKARELAKMLVRVGMGLGLQVAAALTAMDNPLGRNVGHTLEVEEALLCLDGAGPPDLRDLVIRLGGAILWLSGQAETQDQGAARVAAALDDGSALHRFQLMLSAQGVDPGLARALCSGSPTQRRQLLPHARKQEELLSPADGIVECVRALPLACVLHELGAGRSRAGQPIRPGVGAELLVDVGQWLSRGTPWLRVHLDGPALSSQQRRTLLGALVLSDRAPFKAPSPFAELVLPPTTP", "length": 476 }, "evidence": [ { "id": "MGI:3818630", "url": "https://alliancegenome.org/gene/MGI:3818630#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041210-173", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041210-173#orthology", "database": "AGR" }, { "id": "HGNC:10604", "url": "https://alliancegenome.org/gene/HGNC:10604#orthology", "database": "AGR" }, { "id": "SGD:S000000228", "url": "https://alliancegenome.org/gene/SGD:S000000228#orthology", "database": "AGR" }, { "id": "SGD:S000000241", "url": "https://alliancegenome.org/gene/SGD:S000000241#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5RH02-1", "protein_name": "Cytochrome c oxidase assembly factor SCO2", "gene_name": "sco2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLRLRVFDRHKRLWSVLQSTIRGNNISNHIPNTTCRSSAPPHLCARQRAFYSQNSPKTPNPGSSAGIKLRTRLVVTLLFGGGIIGTWWYVHQEKEKRIQMQRLEQLRKVALGQGDFHLLDHTGQRRTKRDFLGHWVLLYFGFTHCPDICPDELEKLTSVVHILDKDPSLPSVQPLFITVDPERDDVSAMARYVKDFHPRLVGLTGSAEEVKQAGRDFRVYASNGPKDEDGDYIVDHSIVIYLVNPDGLFIDYYNRMKNDTQIAESIRNHMKTFVRLFPD", "length": 279 }, "evidence": [ { "id": "MGI:3818630", "url": "https://alliancegenome.org/gene/MGI:3818630#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041210-173", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041210-173#orthology", "database": "AGR" }, { "id": "FB:FBgn0262467", "url": "https://alliancegenome.org/gene/FB:FBgn0262467#orthology", "database": "AGR" }, { "id": "HGNC:10604", "url": "https://alliancegenome.org/gene/HGNC:10604#orthology", "database": "AGR" }, { "id": "SGD:S000000228", "url": "https://alliancegenome.org/gene/SGD:S000000228#orthology", "database": "AGR" }, { "id": "SGD:S000000241", "url": "https://alliancegenome.org/gene/SGD:S000000241#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5SUC9-1", "protein_name": "Cytochrome c oxidase assembly factor SCO1", "gene_name": "Sco1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAALVRAAVVRSQCRQLWRLFPRGHGLRDVAERPRPEEACSCLRSRAFSAGPPPPGAGPEPKGGQAGSHRPKPGPVSWKSLALTFAIGGSLLAGMKYFKKEKIEKLEKQRHRSIGKPLLGGPFSLTTHNGEPKTDKDYLGQWVLIYFGFTHCPDICPEELEKMIEVVEEIDSIPSLPNLTPLFITIDPERDTKEAIATYVKEFSPKLVGLTGTKEEIDGVARAYRVYYSPGPKDEDEDYIVDHTIIMYLIGPDGEFLDYFGQNKKKAEIAGSIAAHMRSHMKKR", "length": 284 }, "evidence": [ { "id": "MGI:106362", "url": "https://alliancegenome.org/gene/MGI:106362#orthology", "database": "AGR" }, { "id": "HGNC:10603", "url": "https://alliancegenome.org/gene/HGNC:10603#orthology", "database": "AGR" }, { "id": "FB:FBgn0262467", "url": "https://alliancegenome.org/gene/FB:FBgn0262467#orthology", "database": "AGR" }, { "id": "RGD:1559538", "url": "https://alliancegenome.org/gene/RGD:1559538#orthology", "database": "AGR" }, { "id": "SGD:S000000228", "url": "https://alliancegenome.org/gene/SGD:S000000228#orthology", "database": "AGR" }, { "id": "SGD:S000000241", "url": "https://alliancegenome.org/gene/SGD:S000000241#orthology", "database": "AGR" }, { "id": "Q9VMX4", "url": "https://omabrowser.org/oma/group/Q9VMX4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VCL2-1", "protein_name": "Cytochrome c oxidase assembly protein SCO2", "gene_name": "Sco2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLALGPKAWPKLSQFKPLLRISGGETLHRNSRHWAGQGQRQGPGLRTRLLITALFGAGLGWAWLAARAEKEQWRQQQRTEALRQAAVGQGDFSLLDHKGQPRCKADFRGQWVLMYFGFTHCPDICPDELEKLVQVVRKLEAEPDLPLVQPVFITVDPERDDVAAMARYVQEFHPRLLGLTGSTEQVAHASRNYRVYYSAGPKDEDQDYIVDHSIAIYLLNPDGLFTDYYGRSRSAEQIVESIRRHIAAFHSVLP", "length": 255 }, "evidence": [ { "id": "MGI:3818630", "url": "https://alliancegenome.org/gene/MGI:3818630#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041210-173", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041210-173#orthology", "database": "AGR" }, { "id": "FB:FBgn0262467", "url": "https://alliancegenome.org/gene/FB:FBgn0262467#orthology", "database": "AGR" }, { "id": "HGNC:10604", "url": "https://alliancegenome.org/gene/HGNC:10604#orthology", "database": "AGR" }, { "id": "SGD:S000000228", "url": "https://alliancegenome.org/gene/SGD:S000000228#orthology", "database": "AGR" }, { "id": "SGD:S000000241", "url": "https://alliancegenome.org/gene/SGD:S000000241#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VYP0-1", "protein_name": "Cytochrome c oxidase assembly factor HCC1", "gene_name": "HCC1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASALCRTASRLRSVQLFRRIRVSSDLLSASSPSPACISDALRHGDFSLPRSFFSLNCGIEMLKMDQRCLLSTSASDTTSKHDSGKPETKSSEKNEKSGGSESSDGGSDHKNERASGKDVRGGPVSWMSFFLLFATGAGLVYYYDTQKKRHIEDINKNSIAVKEGPSAGKAAIGGPFSLIRDDGKRVTEKNLMGKWTILYFGFTHCPDICPDELIKLAAAIDKIKENSGVDVVPVFISVDPERDTVQQVHEYVKEFHPKLIGLTGSPEEIKSVARSYRVYYMKTEEEDSDYLVDHSIVMYLMSPEMNFVKFYGKNHDVDSLTDGVVKEIRQYRK", "length": 334 }, "evidence": [ { "id": "Q9VMX4", "url": "https://omabrowser.org/oma/group/Q9VMX4/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q9VMX4", "url": "https://www.uniprot.org/uniprotkb/Q9VMX4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular copper ion homeostasis", "id": "GO:0006878", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006878", "evidence": [ { "database": "UniProtKB", "id": "Q9VMX4", "url": "https://www.uniprot.org/uniprotkb/Q9VMX4" } ], "pmid": "" }, { "name": "mitochondrial respiratory chain complex IV assembly", "id": "GO:0033617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033617", "evidence": [ { "database": "UniProtKB", "id": "Q9VMX4", "url": "https://www.uniprot.org/uniprotkb/Q9VMX4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "copper ion binding", "id": "GO:0005507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005507", "evidence": [ { "database": "UniProtKB", "id": "Q9VMX4", "url": "https://www.uniprot.org/uniprotkb/Q9VMX4" } ], "pmid": "" }, { "name": "copper 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SV=1 CANONICAL=Q9VMX8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VMX8", "url": "https://www.uniprot.org/uniprotkb/Q9VMX8" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VMX8", "url": "https://www.uniprot.org/uniprotkb/Q9VMX8" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMX8", "url": "https://www.uniprot.org/uniprotkb/Q9VMX8" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMX8", "url": "https://www.uniprot.org/uniprotkb/Q9VMX8" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VMX8", "url": 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Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VMX8", "url": "https://www.uniprot.org/uniprotkb/Q9VMX8" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VMX8", "url": "https://www.uniprot.org/uniprotkb/Q9VMX8" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMX8", "url": "https://www.uniprot.org/uniprotkb/Q9VMX8" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMX8", "url": "https://www.uniprot.org/uniprotkb/Q9VMX8" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VMZ3", "url": "https://www.uniprot.org/uniprotkb/Q9VMZ3" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VMZ3", "url": "https://www.uniprot.org/uniprotkb/Q9VMZ3" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMZ3", "url": "https://www.uniprot.org/uniprotkb/Q9VMZ3" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMZ3", "url": "https://www.uniprot.org/uniprotkb/Q9VMZ3" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VMZ3", "url": "https://www.uniprot.org/uniprotkb/Q9VMZ3" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VMZ3", "url": "https://www.uniprot.org/uniprotkb/Q9VMZ3" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VMZ3", "url": "https://www.uniprot.org/uniprotkb/Q9VMZ3" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMZ3", "url": "https://www.uniprot.org/uniprotkb/Q9VMZ3" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMZ3", "url": "https://www.uniprot.org/uniprotkb/Q9VMZ3" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VMZ3", "url": "https://www.uniprot.org/uniprotkb/Q9VMZ3" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VMZ3", "url": "https://www.uniprot.org/uniprotkb/Q9VMZ3" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], 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"MKQFVVLMCLVALTATAPQGYKYQPQLPALPIGNLRPLTPISSSGIYASGAVPSFPQAGAQPAIGVQPAIQAVQTIVAAPAPAPAPAPLSISLPKETFLTASPQQNLISTVQQQPQQIVYQQQPQQALQTQFVQRPAIVTKDIYIHSAPEENEELRQDEPLLENVPIRKNYRIVFIKAPSQNLKYTAAALKRAQSSNEEKTVIYVLSKKPDLTEIQQQLQVTQSEAKVQKPEVYFIKYKTQEEAQRAQQEIQAQYDALGGATHISDEGVAPIASVSSGSLNLGSFVPQHSQAGQTIIHSQAPTIIQPQGQPIVQLQSINQGVQGVQQQSSFVQKSTSSFAPSAPSRKYVPAKTF", "length": 354, "header": "tr|Q9VMZ5-1|Q9VMZ5_DROME Isoform 1 of TweedleF OS=Drosophila melanogaster OX=7227 GN=TwdlF PE=4 SV=1 CANONICAL=Q9VMZ5-1" }, "isoforms": [ { "isoform_ac": "Q9VMZ5-1", "url": "https://www.uniprot.org/uniprotkb/Q9VMZ5/entry#Q9VMZ5-1", "sequence": { "sequence": "MKQFVVLMCLVALTATAPQGYKYQPQLPALPIGNLRPLTPISSSGIYASGAVPSFPQAGAQPAIGVQPAIQAVQTIVAAPAPAPAPAPLSISLPKETFLTASPQQNLISTVQQQPQQIVYQQQPQQALQTQFVQRPAIVTKDIYIHSAPEENEELRQDEPLLENVPIRKNYRIVFIKAPSQNLKYTAAALKRAQSSNEEKTVIYVLSKKPDLTEIQQQLQVTQSEAKVQKPEVYFIKYKTQEEAQRAQQEIQAQYDALGGATHISDEGVAPIASVSSGSLNLGSFVPQHSQAGQTIIHSQAPTIIQPQGQPIVQLQSINQGVQGVQQQSSFVQKSTSSFAPSAPSRKYVPAKTF", "length": 354, "header": "tr|Q9VMZ5-1|Q9VMZ5_DROME Isoform 1 of TweedleF OS=Drosophila melanogaster OX=7227 GN=TwdlF PE=4 SV=1 CANONICAL=Q9VMZ5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VMZ5", "url": "https://www.uniprot.org/uniprotkb/Q9VMZ5" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VMZ5", "url": "https://www.uniprot.org/uniprotkb/Q9VMZ5" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMZ5", "url": "https://www.uniprot.org/uniprotkb/Q9VMZ5" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMZ5", "url": "https://www.uniprot.org/uniprotkb/Q9VMZ5" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VMZ5", "url": "https://www.uniprot.org/uniprotkb/Q9VMZ5" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VMZ5", "url": "https://www.uniprot.org/uniprotkb/Q9VMZ5" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VMZ5", "url": "https://www.uniprot.org/uniprotkb/Q9VMZ5" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMZ5", "url": "https://www.uniprot.org/uniprotkb/Q9VMZ5" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMZ5", "url": "https://www.uniprot.org/uniprotkb/Q9VMZ5" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VMZ5", "url": "https://www.uniprot.org/uniprotkb/Q9VMZ5" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VMZ5", "url": "https://www.uniprot.org/uniprotkb/Q9VMZ5" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], 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CANONICAL=Q9VMZ6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VMZ6", "url": "https://www.uniprot.org/uniprotkb/Q9VMZ6" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VMZ6", "url": "https://www.uniprot.org/uniprotkb/Q9VMZ6" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMZ6", "url": "https://www.uniprot.org/uniprotkb/Q9VMZ6" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMZ6", "url": "https://www.uniprot.org/uniprotkb/Q9VMZ6" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VMZ6", "url": 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Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VMZ6", "url": "https://www.uniprot.org/uniprotkb/Q9VMZ6" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VMZ6", "url": "https://www.uniprot.org/uniprotkb/Q9VMZ6" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMZ6", "url": "https://www.uniprot.org/uniprotkb/Q9VMZ6" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VMZ6", "url": "https://www.uniprot.org/uniprotkb/Q9VMZ6" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VN06", "url": "https://www.uniprot.org/uniprotkb/Q9VN06" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VN06", "url": "https://www.uniprot.org/uniprotkb/Q9VN06" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VN06", "url": "https://www.uniprot.org/uniprotkb/Q9VN06" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VN06", "url": "https://www.uniprot.org/uniprotkb/Q9VN06" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VN06", "url": 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Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VN06", "url": "https://www.uniprot.org/uniprotkb/Q9VN06" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VN06", "url": "https://www.uniprot.org/uniprotkb/Q9VN06" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi 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} ] } ], "protein_names": [ { "name": "CG14648-PA", "type": "synonym", "evidence": [ { "id": "NP_649466", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649466" } ] }, { "name": "Lost", "type": "synonym", "evidence": [ { "id": "Q9VN21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VN21/entry#names_and_taxonomy" } ] }, { "name": "growl", "type": "synonym", "evidence": [ { "id": "NP_649466", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649466" } ] }, { "name": "lost boys", "type": "synonym", "evidence": [ { "id": "NP_649466", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649466" } ] }, { "name": "lost-PA", "type": "synonym", "evidence": [ { "id": "NP_649466", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649466" } ] }, { "name": "lost", "type": "synonym", "evidence": [ { "id": "NP_649466", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649466" } ] }, { "name": "neverland", "type": "synonym", "evidence": [ { "id": "NP_649466", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649466" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VN21", "url": "https://www.uniprot.org/uniprotkb/Q9VN21" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "lost", "url": "https://www.uniprot.org/uniprotkb/Q9VN21", "locus": { "chromosome": "3R", "start_pos": 4407182, "end_pos": 4403076, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0263594", "url": "https://www.ensemblgenomes.org/id/FBgn0263594" } ] } } ], "crossref": [ { "id": "FB:FBgn0263594", "url": "https://alliancegenome.org/gene/FB:FBgn0263594", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0263594", "url": "https://bgee.org/?page=gene&gene_id=FBgn0263594", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0263594", "url": "https://flybase.org/reports/FBgn0263594", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "40559", "url": "https://www.ncbi.nlm.nih.gov/gene/40559", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VN21", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VN21*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR002698", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002698", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037171", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037171", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG14648", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG14648", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NPMSITW", "url": "https://omabrowser.org/oma/group/NPMSITW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VN21", "url": "https://www.orthodb.org/?gene=Q9VN21", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13017", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13017", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13017:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13017:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01812", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01812", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_649466", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649466", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VN21", "url": "https://www.uniprot.org/uniprotkb/Q9VN21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VN21-1", "url": "https://www.uniprot.org/uniprotkb/Q9VN21-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEDQSNAAPAVAAENGGNTAQEVSSTTQPIEPTKRSLRVQTWKKIQEGKVGIGFNNIFNRIPSFVGADKAAALFANEEEFKKAQHIKVNIDRVLHEFKELALLADKSVYLPSTRESSALCLKVDVLADATEEQKKEALRVQDIQKFRSEIGLDSGLKLDIVVIGSVVVSREGYRIGRGNGFADLDIGLLIELGAITPKTIIVTIVHDMQVVDSLPPNLFQKYDTPVDIIATPTEIIRVPKRLSFPNGVYWELLSERRLKILPVLQQLKEREEKAGKSISLKEEDTDVEQHQNNRRRRGPVRRRIQRGNPGRTTSQTDNEQPQGETAQKRTPRRKGRFVNRRRRTTKSEGDQSGVEAGAKTDDRKLPEAGTDERRSKKNKNSDFCIKLTNLSRDIRVKDLKSELRKRECTPMSISWKGHFGKCFLHFGNRKGVPSTQDDMDKVLKSLNDLSLTITTGGETAPAAAAGEGGEKAESAETATPVQTKTILVNVELIQFGEKKSASSTGANAGAGEDGKADAQNGGEAVTVAGGDVGGARIEAVDTTTV", "length": 545, "header": "tr|Q9VN21-1|Q9VN21_DROME Isoform 1 of Lost OS=Drosophila melanogaster OX=7227 GN=lost PE=1 SV=1 CANONICAL=Q9VN21-1" }, "isoforms": [ { "isoform_ac": "Q9VN21-1", "url": "https://www.uniprot.org/uniprotkb/Q9VN21/entry#Q9VN21-1", "sequence": { "sequence": "MEDQSNAAPAVAAENGGNTAQEVSSTTQPIEPTKRSLRVQTWKKIQEGKVGIGFNNIFNRIPSFVGADKAAALFANEEEFKKAQHIKVNIDRVLHEFKELALLADKSVYLPSTRESSALCLKVDVLADATEEQKKEALRVQDIQKFRSEIGLDSGLKLDIVVIGSVVVSREGYRIGRGNGFADLDIGLLIELGAITPKTIIVTIVHDMQVVDSLPPNLFQKYDTPVDIIATPTEIIRVPKRLSFPNGVYWELLSERRLKILPVLQQLKEREEKAGKSISLKEEDTDVEQHQNNRRRRGPVRRRIQRGNPGRTTSQTDNEQPQGETAQKRTPRRKGRFVNRRRRTTKSEGDQSGVEAGAKTDDRKLPEAGTDERRSKKNKNSDFCIKLTNLSRDIRVKDLKSELRKRECTPMSISWKGHFGKCFLHFGNRKGVPSTQDDMDKVLKSLNDLSLTITTGGETAPAAAAGEGGEKAESAETATPVQTKTILVNVELIQFGEKKSASSTGANAGAGEDGKADAQNGGEAVTVAGGDVGGARIEAVDTTTV", "length": 545, "header": "tr|Q9VN21-1|Q9VN21_DROME Isoform 1 of Lost OS=Drosophila melanogaster OX=7227 GN=lost PE=1 SV=1 CANONICAL=Q9VN21-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VN21", "url": "https://www.uniprot.org/uniprotkb/Q9VN21" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VN21", "url": "https://www.uniprot.org/uniprotkb/Q9VN21" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VN21", "url": "https://www.uniprot.org/uniprotkb/Q9VN21" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VN21", "url": "https://www.uniprot.org/uniprotkb/Q9VN21" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VN21", "url": "https://www.uniprot.org/uniprotkb/Q9VN21" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VN21", "url": "https://www.uniprot.org/uniprotkb/Q9VN21" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VN21", "url": "https://www.uniprot.org/uniprotkb/Q9VN21" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VN21", "url": "https://www.uniprot.org/uniprotkb/Q9VN21" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VN21", "url": "https://www.uniprot.org/uniprotkb/Q9VN21" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VN21", "url": "https://www.uniprot.org/uniprotkb/Q9VN21" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VN21", "url": "https://www.uniprot.org/uniprotkb/Q9VN21" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG14648", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG14648", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LN54-1", "protein_name": "Methenyltetrahydrofolate synthase domain-containing protein", "gene_name": "Mthfsd", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLTSSVRRQALREASLGDVLVMEARAGDVSKQSIRERIWDYMESHNIADFPRPVHHRIPNFKGASRAAEHFPHLHAFSAARTIKVNPDAPQRNARFLVLESRKTLLVPTPRLRTGLFNKIIPPPGATKDILRKCATSQGVRNFSVPVGLDSNVLVDLVVVGSVAVSEKGWRIGKGEGYADLEYAMMVSMGAVHEGTLVVTIVHDCQVVDIPEALLEDHDLTVDYILTPTRVIATGCARPKPTGILWSKVSCEMLTKIPVLRSLREREKRAGTDVTLQAEPGNTQQPAPSTVRRPQDRPQSQPAPSTVRRPQDRPQSQAGFRGRSHSSLEGTDTHLAATVCLGNLPYSARVRELKRALQELGAVPLRLTWQGPQHRAILHYTDSAAAQQAASLLQGLRLGDNALRVSLGQQRDT", "length": 414 }, "evidence": [ { "id": "RGD:1584226", "url": "https://alliancegenome.org/gene/RGD:1584226#orthology", "database": "AGR" }, { "id": "HGNC:25778", "url": "https://alliancegenome.org/gene/HGNC:25778#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-3513", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-3513#orthology", "database": "AGR" }, { "id": "MGI:2679252", "url": "https://alliancegenome.org/gene/MGI:2679252#orthology", "database": "AGR" }, { "id": "FB:FBgn0263594", "url": "https://alliancegenome.org/gene/FB:FBgn0263594#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q0P464-1", "protein_name": "Methenyltetrahydrofolate synthase domain-containing protein", "gene_name": "mthfsd", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEPVIKINQGETKWDVRHKVWNYIEVKNLANFPRPVHNRIPNFKGALEACNKVAQLEIFIESAVVKVDPDKPMEGVRLAALKARKSLLVPTPRLRFGLFNRITPPKGATKETLRVCSTSQGIKEFSVPVGLDDKVQVDLVVVGSVAVSEKGYRIGKGEGFADMEYAMMACMGSVTESTWVITVVHDCQVMDIPEELIERHDLMVDFIITATRVIKTECKHPKPQGIIWSMLHKEELKKIPILKKLRTLEQEAGKDVALKLIHAGEDEYRKSKELQWQSHPKADLEFKCLASNSDRCSGFEPKFPTTTVYLSDIPPALRVSELKGLLREQEVVPLQIRWQGAKRKAFLLYADFTGAERATAILQKLFINGHTIQAKCVSSQKM", "length": 382 }, "evidence": [ { "id": "RGD:1584226", "url": "https://alliancegenome.org/gene/RGD:1584226#orthology", "database": "AGR" }, { "id": "HGNC:25778", "url": "https://alliancegenome.org/gene/HGNC:25778#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-3513", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-3513#orthology", "database": "AGR" }, { "id": "MGI:2679252", "url": "https://alliancegenome.org/gene/MGI:2679252#orthology", "database": "AGR" }, { "id": "FB:FBgn0263594", "url": "https://alliancegenome.org/gene/FB:FBgn0263594#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2M296-1", "protein_name": "Methenyltetrahydrofolate synthase domain-containing protein", "gene_name": "MTHFSD", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPRAVGVSKQDIREQIWGYMESQNLADFPRPVHHRIPNFKGSYLACQNIKDLDVFARTQEVKVDPDKPLEGVRLLVLQSKKTLLVPTPRLRTGLFNKITPPPGATKDILRKCATSQGVRNYSVPIGLDSRVLVDLVVVGSVAVSEKGWRIGKGEGYADLEYAMMVSMGAVSKETPVVTIVHDCQVVDIPEELVEEHDITVDYILTPTRVIATGCKRPKPMGITWFKISLEMMEKIPILRSLRAREQQAGKDVTLQGEHQHLPEPGCQQTVPLSVGRRPPDTPGPETNSMEAAPGSPPGEGAPLAADVYVGNLPGDARVSDLKRALRELGSVPLRLTWQGPRRRAFLHYPDSAAAQQAVSCLQGLRLGTDTLRVALARQQRDK", "length": 383 }, "evidence": [ { "id": "RGD:1584226", "url": "https://alliancegenome.org/gene/RGD:1584226#orthology", "database": "AGR" }, { "id": "HGNC:25778", "url": "https://alliancegenome.org/gene/HGNC:25778#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-3513", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-3513#orthology", "database": "AGR" }, { "id": "MGI:2679252", "url": "https://alliancegenome.org/gene/MGI:2679252#orthology", "database": "AGR" }, { "id": "FB:FBgn0263594", "url": "https://alliancegenome.org/gene/FB:FBgn0263594#orthology", "database": "AGR" }, { "id": "Q9VN21", "url": "https://omabrowser.org/oma/group/Q9VN21/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3URQ7-1", "protein_name": "Methenyltetrahydrofolate synthase domain-containing protein", "gene_name": "Mthfsd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METQEGVSKQSIRERIWDYMESHDIADFPRPVHHRIPNFKGAAQAAGHLPHLQAFHVARTIKVNPDAPQRNARFLVLESKKTLLVPTPRLRTGLFNKITPPPGATKDILRKCATSQGVRNFSVPVGLDSSVLVDLVVVGSVAVSEKGWRIGKGEGYADLEYAMMVSMGAVHKGTPVVTIVHDCQVVDIPEALVEDHDLTVDYILTPTRVITTGCARPKPTGIMWSKVSCEMLTKIPVLRNLREREKQAGKDVTLRDEPGSQQPAPGPIRRPQDRPQTGSRGGSRSPLQGADTQLAATVCVGNLPFTTRVRELKRVLQELGVVPLRLTWQGPQHRAVLHYTDSAAAQQAASLLQGLRLGANALRVSLGQQRDM", "length": 372 }, "evidence": [ { "id": "RGD:1584226", "url": "https://alliancegenome.org/gene/RGD:1584226#orthology", "database": "AGR" }, { "id": "HGNC:25778", "url": "https://alliancegenome.org/gene/HGNC:25778#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-3513", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-3513#orthology", "database": "AGR" }, { "id": "MGI:2679252", "url": "https://alliancegenome.org/gene/MGI:2679252#orthology", "database": "AGR" }, { "id": "FB:FBgn0263594", "url": "https://alliancegenome.org/gene/FB:FBgn0263594#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VN21", "url": "https://www.uniprot.org/uniprotkb/Q9VN21" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VN21", "url": "https://www.uniprot.org/uniprotkb/Q9VN21" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "Q9VN21", "url": "https://www.uniprot.org/uniprotkb/Q9VN21" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "Q9VN21", "url": "https://www.uniprot.org/uniprotkb/Q9VN21" } ], "pmid": "" }, { "name": "precatalytic spliceosome", "id": "GO:0071011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071011", "evidence": [ { "database": "UniProtKB", "id": "Q9VN21", "url": "https://www.uniprot.org/uniprotkb/Q9VN21" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "anterior/posterior pattern specification", "id": "GO:0009952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009952", "evidence": [ { "database": "UniProtKB", "id": "Q9VN21", "url": "https://www.uniprot.org/uniprotkb/Q9VN21" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "Q9VN21", "url": "https://www.uniprot.org/uniprotkb/Q9VN21" } ], "pmid": "" }, { "name": "pole cell development", "id": "GO:0007277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007277", "evidence": [ { "database": "UniProtKB", "id": "Q9VN21", "url": "https://www.uniprot.org/uniprotkb/Q9VN21" } ], "pmid": "" }, { "name": "pole plasm mRNA localization", "id": "GO:0019094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019094", "evidence": [ { "database": "UniProtKB", "id": "Q9VN21", "url": "https://www.uniprot.org/uniprotkb/Q9VN21" } ], "pmid": "" }, { "name": "pole plasm oskar mRNA localization", "id": "GO:0045451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045451", "evidence": [ { "database": "UniProtKB", "id": "Q9VN21", "url": "https://www.uniprot.org/uniprotkb/Q9VN21" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 389, "end_pos": 391, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VN56-1", "uniprot_ac": "Q9VN56", "uniprot_id": "Q9VN56_DROME", "mass": { "chemical_mass": 58076.0, "monoisotopic_mass": 58076.0 }, "refseq": { "ac": "NP_649494", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649494" }, "gene_names": [ { "name": "Dmel\\CG14655", "type": "recommended", "evidence": [ { "id": "Q9VN56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VN56" } ] }, { "name": "CG14655", "type": "synonym", "evidence": [ { "id": "NP_649494", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649494" }, { "id": "Q9VN56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VN56" } ] }, { "name": "Dmel\\CG14655", "type": "synonym", "evidence": [ { "id": "NP_649494", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649494" } ] }, { "name": "Dmel_CG14655", "type": "synonym", "evidence": [ { "id": "Q9VN56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VN56" } ] } ], "protein_names": [ { "name": "C2H2-type domain-containing protein", "type": "recommended", "evidence": [ { "id": "Q9VN56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VN56/entry#names_and_taxonomy" } ] }, { "name": "CG14655-PA", "type": "synonym", "evidence": [ { "id": "NP_649494", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649494" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_649494", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649494" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VN56", "url": "https://www.uniprot.org/uniprotkb/Q9VN56" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG14655", "url": "https://www.uniprot.org/uniprotkb/Q9VN56", "locus": { "chromosome": "3R", "start_pos": 4777497, "end_pos": 4780302, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0037275", "url": "https://www.ensemblgenomes.org/id/FBgn0037275" } ] } } ], "crossref": [ { "id": "FB:FBgn0037275", "url": "https://alliancegenome.org/gene/FB:FBgn0037275", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0037275", "url": "https://bgee.org/?page=gene&gene_id=FBgn0037275", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0037275", "url": "https://flybase.org/reports/FBgn0037275", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "40594", "url": "https://www.ncbi.nlm.nih.gov/gene/40594", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VN56", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VN56*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050636", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050636", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG14655", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG14655", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IHLFTHT", "url": "https://omabrowser.org/oma/group/IHLFTHT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VN56", "url": "https://www.orthodb.org/?gene=Q9VN56", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47772", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47772", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47772:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47772:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12874", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12874", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_649494", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649494", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VN56", "url": "https://www.uniprot.org/uniprotkb/Q9VN56", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VN56-1", "url": "https://www.uniprot.org/uniprotkb/Q9VN56-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCSTSVLCPLCAVPSFGSIDALQQRLIKAANGPLACPFANCKELFLGLDKLTIHLFSHTSLMAQEGNESPANGQPASSRGFLAAAPPKRRAKRTRSKPVVPTPPPVRTTPPAHCDICEFSFRNTELRDMHVRLVHENAEGEPKQKEPQQKEPDQEPYKCHLCSKTFRMKGSLRIHLKVVHMMGVPCSNPNPNPNPSPTPASTTSAVTATPKLSICDRIRHTEPGALGNGNNSTCTASQPYALSGALSMLQQSPSSPESGTATPKLWECDVCSKSFTTKYFLKKHKRLHTGEMPYTCEICARTFTFQQSYHKHLLYHSEVKPHVCGVCGRAFKELSTLHNHQRIHSGEKPFKCEVCGKCFRQRVSFLVHTRIHTGVMPYKCELCQKTFRYKVSQRTHRCPTEEAQTPEQLIKAFLEGNDSHTQPSPASAEIAAINSSSIVDPEQEALLSQSIDDIVVEQCQKLGICGVEPREEGQLISLQPVAVVHFSGNGSPLQQLQNLRIYSPQQTELPSSDGEVFQRFLMDAT", "length": 525, "header": "tr|Q9VN56-1|Q9VN56_DROME Isoform 1 of C2H2-type domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG14655 PE=4 SV=1 CANONICAL=Q9VN56-1" }, "isoforms": [ { "isoform_ac": "Q9VN56-1", "url": "https://www.uniprot.org/uniprotkb/Q9VN56/entry#Q9VN56-1", "sequence": { "sequence": "MCSTSVLCPLCAVPSFGSIDALQQRLIKAANGPLACPFANCKELFLGLDKLTIHLFSHTSLMAQEGNESPANGQPASSRGFLAAAPPKRRAKRTRSKPVVPTPPPVRTTPPAHCDICEFSFRNTELRDMHVRLVHENAEGEPKQKEPQQKEPDQEPYKCHLCSKTFRMKGSLRIHLKVVHMMGVPCSNPNPNPNPSPTPASTTSAVTATPKLSICDRIRHTEPGALGNGNNSTCTASQPYALSGALSMLQQSPSSPESGTATPKLWECDVCSKSFTTKYFLKKHKRLHTGEMPYTCEICARTFTFQQSYHKHLLYHSEVKPHVCGVCGRAFKELSTLHNHQRIHSGEKPFKCEVCGKCFRQRVSFLVHTRIHTGVMPYKCELCQKTFRYKVSQRTHRCPTEEAQTPEQLIKAFLEGNDSHTQPSPASAEIAAINSSSIVDPEQEALLSQSIDDIVVEQCQKLGICGVEPREEGQLISLQPVAVVHFSGNGSPLQQLQNLRIYSPQQTELPSSDGEVFQRFLMDAT", "length": 525, "header": "tr|Q9VN56-1|Q9VN56_DROME Isoform 1 of C2H2-type domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG14655 PE=4 SV=1 CANONICAL=Q9VN56-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 102, "start_aa": "Thr", "end_pos": 102, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr102", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 198, "start_aa": "Thr", "end_pos": 198, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr198", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VN56", "url": "https://www.uniprot.org/uniprotkb/Q9VN56" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VN56", "url": "https://www.uniprot.org/uniprotkb/Q9VN56" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VN56", "url": "https://www.uniprot.org/uniprotkb/Q9VN56" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VN56", "url": "https://www.uniprot.org/uniprotkb/Q9VN56" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VN56", "url": "https://www.uniprot.org/uniprotkb/Q9VN56" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VN56", "url": "https://www.uniprot.org/uniprotkb/Q9VN56" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VN56", "url": "https://www.uniprot.org/uniprotkb/Q9VN56" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VN56", "url": "https://www.uniprot.org/uniprotkb/Q9VN56" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VN56", "url": "https://www.uniprot.org/uniprotkb/Q9VN56" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VN56", "url": "https://www.uniprot.org/uniprotkb/Q9VN56" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VN56", "url": "https://www.uniprot.org/uniprotkb/Q9VN56" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG14655", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG14655", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZTE2-1", "protein_name": "Zinc finger protein 108", "gene_name": "Zfp108", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKLQEAVTFRDVAVVFSKEEMGLLDAAQRKLYHDVMLENLRNLLAVGGQSPSKIETLHKTGVRCLSLGKLSCWQITGHDANKLARAPEDVINTQEQGSHFLERCHRGAEEPSQVSADDDSAESLTSNHSSISENQEFLSGRAQSSLSETHLSERRDSGKHCPQTPVKTKPQPLALGVDILSFISHQDNDILHERDKVHSSGDCDEVICPLSQLTQDCDYTERKAYQCSQGQNAFIDSSFLELHQQVLLEMKSSGHTAHEDTRRSSSVPIQQSIHPGEKRYWCQECGKGFSQSSALQTHRRVHTGEKPYQCDSCGRGFSRNSDLNIHRRVHTGENLHKCEVCGKGFTKWDHLQIHQRIHTGEKPYKCGDCGKRFSCSWNLHTHQRVHTEEKPYKCDECGKRFSLSFNLHSHQRIHTGEKPYKCEECGKGFSSASSFQRHQRVHTGEKPFVCNVCGKSFSQSSNFQAHQRVHTREKPYRCDVCGKHSTWSLHSHQRVHTGEKPFHCSVCGKTFSRSSHFLDHQRIHTGEKPYRCDVCGKRFPWSLSLHSHQRVHTGEKPYKCEECGKGFSHASSLQAHQSVHTGEKPFKCNVCQKQFSKASNLQAHQRVHTGEKPYKCDTCGKAFSQRSSLQVHQRIHTGEKPFKCEECGKGFSWSAGLTAHQRVHTGEKPYTCQQCGKGFSQASYFHTHQRVHTGEKPYMCQQCGKRFSQASHFHTHQRVHTGQRP", "length": 726 }, "evidence": [ { "id": "RGD:1564214", "url": "https://alliancegenome.org/gene/RGD:1564214#orthology", "database": "AGR" }, { "id": "FB:FBgn0037275", "url": "https://alliancegenome.org/gene/FB:FBgn0037275#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8N1YZN8-1", "protein_name": "Zinc finger protein 692", "gene_name": "znf692", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSSTKETVLRQRRRELDARRSKSRVRLGSCLQSWAQLKDKLGFSLHSELAQHLLESYVSRVCMKCSGDGKEETVSTTKESLQELILMVHNHGQTCPLPPVLQCRPVQKTKLSTRSQSGRIEAATEPKKLAEADECFKYTCEDGHHFMWCPFNLEKVLISKNEGDKITSEQGKRQMKEPVTDTERQEMMTRLKTRQQQREDAGTNTNKMLGQNKNADVTETLEAQDKNDLASDFSYSEHGSPADSDEMTVDVPVSHTDSYEEFAVLNLTNRGTQSSADHTEKLSVSKKAGILQSNSSQSLKKDMSQIGGKRKRKSTSKLILSCEFDGCDKIFSSRQYLNHHIKYQHLHQKTFTCSHPSCRKSFNFKKHLKEHEKLHSNQRDYICEFCARAFRTSSNLIIHRRIHTGEKPLQCEVCGFTCRQKASLNWHMRKHNAESTYQFPCEICGRRFEKRDNVTAHRSKSHPDYNTGTLERSLPLPPSDPLLHPSRHRGSSPSVSKNQPTAE", "length": 503 }, "evidence": [ { "id": "HGNC:26049", "url": "https://alliancegenome.org/gene/HGNC:26049#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABK0L735-1", "protein_name": "Zinc finger and BTB domain containing 26", "gene_name": "Zbtb26", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSERSDLLHFKFENYGDSMLQKMNKLREENKFCDVTVLIDDVEVQGHKIVFAAGSPFLRDQFLLNDSREVKISILQSSEVGRQLLLSCYSGVLEFPEMELVNYLTAASFLQMSHIVERCTQALWKFIKPKQPMDSKEGSEPQSASPQSKEQQGDARGSPKQDLPCIHPSEDSMDMEDSDIQIVKVESIGDVSEDRSKKDQNQYISSEPTALHSSEPQHSLINSTVENRVNELDQSHLHNYALSYTGNDDIIMTSKDVFGPNIRGVDKGLQWHHQCPKCTRVFRHLENYANHLKMHKLFMCLLCGKTFTQKGNLHRHMRVHAGIKPFQCKICGKTFSQKCSLQDHLNLHSGDKPHKCNYCDMVFAHKPVLRKHLKQLHGKNSFDNANERSVQDLTVDFDSFACTTVTDSNCQPQPDATQVLDAGKLTQAVLSLRSDSTCVN", "length": 440 }, "evidence": [ { "id": "HGNC:23383", "url": "https://alliancegenome.org/gene/HGNC:23383#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F6WEQ6-1", "protein_name": "Zinc finger protein 692", "gene_name": "Znf692", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASPVADASRRRREKRRQLDARRSKCRIRLGGHMEQWCLLKERLGFSLHSQLAKFLLDRYTSSGCVLCAGPEPVPQKGLQYLVLLSHTHSRECSLVPGLRGPGGGEGELVWECSAGHTFSWEPSLIPTPSEVPKQAPLTHTTERTWCSEARRKQEAEGLECEHRERTQETRLSRRVEPPLETDPSVGEDQVVEEEEEEEEEEEEEELLSDASPWTYSSSPDDSEPDVPRPPPSPVTHTPKEGEIPPVPATLPTPCAVLASLGSTAALTSDTEVQMELSRTSQVPAELQMTESLDSPGSQAQSAPNPTCDEDTAQIGLRRIRKAAKRELMPCDFPGCGRIFSNRQYLNHHKKYQHIHQKSFCCPEPACGKSFNFKKHLKEHVKLHSDARDYICEFCARSFRTSSNLVIHRRIHTGEKPLQCEICGFTCRQKASLNWHRRKHAETAAALRFPCEFCGKRFEKPDSVVAHCSKSHPALLPVQESPGSLGSSPSISAPEPLQSPEGTSFSTSYDSNPAPSTSISSPGVPAPRNTEKS", "length": 533 }, "evidence": [ { "id": "HGNC:26049", "url": "https://alliancegenome.org/gene/HGNC:26049#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P15619-1", "protein_name": "Serendipity locus protein H-1", "gene_name": "wdn", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEGGKGEGKRMKEEAPSKKLPPKIYGGDAGTPTKAAHDEILSSLLRINNFDSISSIKDESLDIDLSACVTISSASLVNGNSLSSTDFWRVLDESAQNNTELNLSSDVCRDDLAATSSSTVPSTLTSDNHSSSEFSVTFLRPEPPNAFTNSPFKKTSSSGTSTPVKLSPEQLHQQHQLQMPQSQLLQRKPKLPAATAVRLKVFKEEPPEEKHPPEQVVTKVEVCESELLPPSFTIFQQAKSAESVADAASMPPPAASETKPLEVDPAPLHKCLDCNGLLLETPDEVAKHEAAAHRLRLTYRCSECQREFELLAGLKKHLKTHRTEGRKDTWKKCPDCGKCLKLGSMWMHRKIHSDNKKYQCDICGQKFVQKINLTHHARIHSSEKPYECPECQKRFQERSHLQRHQKYHAQTRSYRCEKCGKMYKTERCLKVHNLVHLEQRPFACTVCDKSFISNSKLKQHSNIHTGMRPFKCNYCPRDFTNFPNWLKHTRRRHKVDHKTGEHLENIPSYCSKKSTTNKAQKAAAAAAAAAAASSAVNPNELSASSELKAKANLTSTAAPAPAKQARKKKQPQQATLAALGITLPAGTALQQVHPVPLAQQHQQELTTVLVPLAPPAPKQTKAKRERKQLAPKQLQQKPQLLQQGQPQQSSLEPIPAVPQIKKEPVQTQGPFLDLHGLSLTSAEELIMEQALEMEECGLYDAPNANTEMGTSDNAISDSAAALHFQIKNELPDELLPDDDFLPCKPSDRLPCPSLESSPFSSPASMELTAVSCASSVAISTNALPVRSGNYYLPAFTLNAHGKLSSTGNGVQSVTTSLAQTPSVSMVNVPLLVRSNQMLPSVDTLLFTNQTGGSRFFAGKSATAATPHLT", "length": 869 }, "evidence": [ { "id": "HGNC:26049", "url": "https://alliancegenome.org/gene/HGNC:26049#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P41696-1", "protein_name": "Transcription factor AZF1", "gene_name": "AZF1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MPPPTAQFMGPTQAGQNESQNQSSGEAGEQNQEHGQGPTPILNQSQPASSQPQHQQQRNESISYYTNFNQPRYSTDASINSFLNISDNVPVTSTGGPSSGGAYSNLPRLSTSSTHQPPDLSQIGRGFSIVNNLFPQQQQLQNQHRQQQQQQQQQSHQQPPFKTPSFSTGLTGSSSQYQFLPRNDNTSQPPSKRNSVYLGPNDGPDFEFFSMQQSQQPQFQPSSRRESNSMRPPLLIPAATTKSQSNGTNNSGNMNTNADYESFFNTGTNNSNSNQNPYFLSSRNNSLKFNPEDFDFQFKRRNSFVRGTLDHSSQNAFIPESRLNSLSVNNKANGDPVADNVTNNMKGKSNEVDNDDGNDSSNNNNNNNNNNNNENNNDNNNDNNDNSINSATSTNIPNQEDHSLASTDTTSNSRKDLKEIEQRLRKHLNDEDNYSSAISRPLDKNDVIEGSEGLNKHIDESGMQPNIIKKRKKDDSTVYVKNEMPRTDPPMSKDNSTSAEGAAMANFSGKEPPIPDISSVSDDATNLIGATKVDQLMLIIQARKKGFTEKVNTTQDGDLLFNQTMDILPPKSELVGGVEKPKGTQNTRAVKKHECPYCHRLFSQATHLEVHVRSHIGYKPFVCDYCGKRFTQGGNLRTHERLHTGEKPYSCDICDKKFSRKGNLAAHLVTHQKLKPFVCKLENCNKTFTQLGNMKAHQNRFHKETLNALTAKLAEMNPSENIPLEERQLLEYFASIYKNSNRGIKGRGKGVGTKKSTISSPENHPASTILNPNTNANNAIANDSENNGNPEGNIDSSSNSNPGSHSMISPTQKDMGTLQSQFIQNNFNNSVNSSNPSNQPIINYNYTTLPHSRLGSSSSSNTNNNNSNFSVGAAPGVLMAPTTNNDFSFNLDQSNDNERSQQEQVRFKNINYKS", "length": 914 }, "evidence": [ { "id": "HGNC:26049", "url": "https://alliancegenome.org/gene/HGNC:26049#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q14590-1", "protein_name": "Zinc finger protein 235", "gene_name": "ZNF235", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTKFQEAVTFKDVAVAFTEEELGLLDSAQRKLYRDVMLENFRNLVSVGHQSFKPDMISQLEREEKLWMKELQTQRGKHSGDRNQNEMATLHKAGLRCFSLGELSCWQIKRHIASKLARSQDSMINIEGKSSQFPKHHDSPCQVGAGESIQASVDDNCLVNHIGDHSSIIENQEFPTGKVPNSWSKIYLNETQNYQRSCKQTQMKNKLCIFAPYVDIFSCISHHHDDNIVHKRDKVHSNSDCGKDTLKVSPLTQRSIHTGQKTYQGNECEEAFNDSSSLELHKQVHLGKKSPACSTHEKDTSYSSGIPVQQSVRTGKKRYWCHECGKGFSQSSNLQTHQRVHTGEKPYTCHECGKSFNQSSHLYAHLPIHTGEKPYRCDSCGKGFSRSTDLNIHCRVHTGEKPYKCEVCGKGFTQRSHLQAHERIHTGEKPYKCGDCGKRFSCSSNLHTHQRVHTEEKPYKCDECGKCFSLSFNLHSHQRVHTGEKPYKCEECGKGFSSASSFQSHQRVHTGEKPFRCNVCGKGFSQSSYFQAHQRVHTGEKPYKCEVCGKRFNWSLNLHNHQRVHTGEKPYKCEECGKGFSQASNLQAHQSVHTGEKPFKCDACQKRFSQASHLQAHQRVHTGEKPYKCDTCGKAFSQRSNLQVHQIIHTGEKPFKCEECGKEFSWSAGLSAHQRVHTGEKPYTCQQCGKGFSQASHFHTHQRVHTGERPYICDVCCKGFSQRSHLIYHQRVHTGGNL", "length": 738 }, "evidence": [ { "id": "RGD:1564214", "url": "https://alliancegenome.org/gene/RGD:1564214#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3U381-1", "protein_name": "Zinc finger protein 692", "gene_name": "Znf692", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASPVADASRRRREKRRQLDARRSKCRIRLGGHMEQWCLLKERLGFSLHSQLAKFLLDRYTSSGCVLCAAPEPGPRKGLQYLVLLSHTHSRECGLVPGLRGPGGGEGELVWECSAGHTFSWEPSLIPAPSDVPKQAPLTHTTERAWCSEARRKQEAQGLECEQRERTQETRLSRRVDSPLEIDPPLGEDQDVEEEEEEEEEEEELLSDASPWTYSSSPDDSEPDVPRPPPSPVTHTPKEGEVSPVPATLPTPCAVLASVGSPDALTSDTEVRLELSRTPQVPAELHMTESLESPGSQAQSAPNPTWDEDTAQIGLRRIRKAAKRELMPCDFPGCGRIFSNRQYLNHHKKYQHIHQKSFCCPEPACGKSFNFKKHLKEHVKLHSDTRDYICEFCARSFRTSSNLVIHRRIHTGEKPLQCEICGFTCRQKASLNWHRRKHAETAAALRFPCEFCGKRFEKPDSVVAHCSKSHPALLPAQEPPGSLVSSPSISAPESLQSPEGASISTTSDSNPASSTSISSPGVPDPRNREKS", "length": 531 }, "evidence": [ { "id": "HGNC:26049", "url": "https://alliancegenome.org/gene/HGNC:26049#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q61116-1", "protein_name": "Zinc finger protein 235", "gene_name": "Znf235", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTKLQEMVTFRDVAVVFSEEELGLLDAAQRKLYHDVMLENFRNLLAVGCQSPNKMAPLDTTGIRCLPLGQLPCWQMTSHDVNKLARAPEDGINTPGKGPHLLEQCHSSCHWGAEQPSQAPEDDGCLENLPSNHSSSSDNQEFLSGRAQSSWSKAHFSERWNHEKHCPQTLVKTKSQLLAPGVNILGCISHHDHNILHKRDKVPSSGDCDQVIFPMTLLTQHCVYREQKAYQCSRGQEVFSDSPSLELHQQTLLGKKSPVHSTHKDTRHSPSVPIQPSVHPGRKRYWCHECGKGFRQSSALQTHQRVHTGEKPYRCDSCGKGFSRSSDLNIHRRVHTGEKPYKCEVCGKGFTQWAHLQAHERIHTGEKPYKCGDCGKRFSCSSNLHTHQRVHTEEKPYECNECGKRFSLSGNLDIHQRVHTGEKPYKCEECGKGFSSASSFQSHQRVHTGEKPFHCSVCGKNFSRSSHFLDHQRIHTGEKPYRCEVCGKRFPWSLSLHSHQSVHTGKKPYKCGECGKGFSHASSLQAHHSVHTGEKPFKCNVCQKQFSKTSNLQAHQRVHTGEKPYKCDTCGKAFSQKSSLQVHQRIHTGEKPFKCEECGKEFRWSVGLSSHQRVHTGEKPYTCQQCGKGFSQASYFHMHQRVHTI", "length": 645 }, "evidence": [ { "id": "RGD:1564214", "url": "https://alliancegenome.org/gene/RGD:1564214#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BU19-1", "protein_name": "Zinc finger protein 692", "gene_name": "ZNF692", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASSPAVDVSCRRREKRRQLDARRSKCRIRLGGHMEQWCLLKERLGFSLHSQLAKFLLDRYTSSGCVLCAGPEPLPPKGLQYLVLLSHAHSRECSLVPGLRGPGGQDGGLVWECSAGHTFSWGPSLSPTPSEAPKPASLPHTTRRSWCSEATSGQELADLESEHDERTQEARLPRRVGPPPETFPPPGEEEGEEEEDNDEDEEEMLSDASLWTYSSSPDDSEPDAPRLLPSPVTCTPKEGETPPAPAALSSPLAVPALSASSLSSRAPPPAEVRVQPQLSRTPQAAQQTEALASTGSQAQSAPTPAWDEDTAQIGPKRIRKAAKRELMPCDFPGCGRIFSNRQYLNHHKKYQHIHQKSFSCPEPACGKSFNFKKHLKEHMKLHSDTRDYICEFCARSFRTSSNLVIHRRIHTGEKPLQCEICGFTCRQKASLNWHQRKHAETVAALRFPCEFCGKRFEKPDSVAAHRSKSHPALLLAPQESPSGPLEPCPSISAPGPLGSSEGSRPSASPQAPTLLPQQ", "length": 519 }, "evidence": [ { "id": "HGNC:26049", "url": "https://alliancegenome.org/gene/HGNC:26049#orthology", "database": "AGR" }, { "id": "FB:FBgn0037275", "url": "https://alliancegenome.org/gene/FB:FBgn0037275#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9HCK0-1", "protein_name": "Zinc finger and BTB domain-containing protein 26", "gene_name": "ZBTB26", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSERSDLLHFKFENYGDSMLQKMNKLREENKFCDVTVLIDDIEVQGHKIVFAAGSPFLRDQFLLNDSREVKISILQSSEVGRQLLLSCYSGVLEFPEMELVNYLTAASFLQMSHIVERCTQALWKFIKPKQPMDSKEGCEPQSASPQSKEQQGDARGSPKQDSPCIHPSEDSMDMEDSDIQIVKVESIGDVSEVRSKKDQNQFISSEPTALHSSEPQHSLINSTVENRVSEIEQNHLHNYALSYTGSDNIIMASKDVFGPNIRGVDKGLQWHHQCPKCTRVFRHLENYANHLKMHKLFMCLLCGKTFTQKGNLHRHMRVHAGIKPFQCKICGKTFSQKCSLQDHLNLHSGDKPHKCNYCDMVFAHKPVLRKHLKQLHGKNSFDNANERNVQDLTVDFDSFACTTVTDSKGCQPQPDATQVLDAGKLAQAVLNLRNDSTCVN", "length": 441 }, "evidence": [ { "id": "HGNC:23383", "url": "https://alliancegenome.org/gene/HGNC:23383#orthology", "database": "AGR" }, { "id": "FB:FBgn0037275", "url": "https://alliancegenome.org/gene/FB:FBgn0037275#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": 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Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VNB9", "url": "https://www.uniprot.org/uniprotkb/Q9VNB9" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VNB9", "url": "https://www.uniprot.org/uniprotkb/Q9VNB9" } ], "reference": [ { "type": "PubMed", 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"MWQFENKNATKMKTSQNEMPDKDKSFRRHSLSPRSLSAIFFHSTGLHLDDGVAQWLSINVKEDITNLLNEAGKYMRRIRDRRLQLSHIQHAVRMHDDLCYDIFFRLVHCDDCKMPPSQKVLKTVREAVTAEKKDELLVSYPESVQESVPEPVPETSLEPPPMHTGWLKVEQVLLKPSKRYPLSMEQQNFFELVTEACVGDLESRRVLALKAISTDPSLEELLPRLTKFIADAVAINVAQQNLPLLLYLMRMVRALLGNQRFSLLQYLHLLLPAVLSCLLAKQVCASPNSEDHWALREYSGNIMAHIVRQFDAADNGILPRVIGVYNKALLKKPLTTVFGAVIGLGKMGNHAVRACILPQLKYLSEHIDSHMAASNDSPSSSVDRQAVKYIRHRLMKMCSPVLMGIHQPPDLPEEFMERYGSLGTLMSDGVTVMRTKKQAVAAAKAEAELKLKNMATEHLNSRGKGSRSVGSNDLVSGTQLPKNGIRPTSQAPKSVYSISVNGQTVKISTPNLCNTMLQHQKKDLFSKPSDFVVPQLVVNQFKNGLIPSNSQRSSSPARNVIHLKPNNDHPSKMALFLRQAITADCPIIT", "length": 589, "header": "tr|Q9VND0-1|Q9VND0_DROME Isoform 1 of Meiosis I arrest, isoform C OS=Drosophila melanogaster OX=7227 GN=mia PE=3 SV=3 CANONICAL=Q9VND0-1" }, "isoforms": [ { "isoform_ac": "Q9VND0-1", "url": "https://www.uniprot.org/uniprotkb/Q9VND0/entry#Q9VND0-1", "sequence": { "sequence": "MWQFENKNATKMKTSQNEMPDKDKSFRRHSLSPRSLSAIFFHSTGLHLDDGVAQWLSINVKEDITNLLNEAGKYMRRIRDRRLQLSHIQHAVRMHDDLCYDIFFRLVHCDDCKMPPSQKVLKTVREAVTAEKKDELLVSYPESVQESVPEPVPETSLEPPPMHTGWLKVEQVLLKPSKRYPLSMEQQNFFELVTEACVGDLESRRVLALKAISTDPSLEELLPRLTKFIADAVAINVAQQNLPLLLYLMRMVRALLGNQRFSLLQYLHLLLPAVLSCLLAKQVCASPNSEDHWALREYSGNIMAHIVRQFDAADNGILPRVIGVYNKALLKKPLTTVFGAVIGLGKMGNHAVRACILPQLKYLSEHIDSHMAASNDSPSSSVDRQAVKYIRHRLMKMCSPVLMGIHQPPDLPEEFMERYGSLGTLMSDGVTVMRTKKQAVAAAKAEAELKLKNMATEHLNSRGKGSRSVGSNDLVSGTQLPKNGIRPTSQAPKSVYSISVNGQTVKISTPNLCNTMLQHQKKDLFSKPSDFVVPQLVVNQFKNGLIPSNSQRSSSPARNVIHLKPNNDHPSKMALFLRQAITADCPIIT", "length": 589, "header": "tr|Q9VND0-1|Q9VND0_DROME Isoform 1 of Meiosis I arrest, isoform C OS=Drosophila melanogaster OX=7227 GN=mia PE=3 SV=3 CANONICAL=Q9VND0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VND0", "url": "https://www.uniprot.org/uniprotkb/Q9VND0" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VND0", "url": "https://www.uniprot.org/uniprotkb/Q9VND0" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VND0", "url": "https://www.uniprot.org/uniprotkb/Q9VND0" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VND0", "url": "https://www.uniprot.org/uniprotkb/Q9VND0" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VND0", "url": "https://www.uniprot.org/uniprotkb/Q9VND0" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VND0", "url": "https://www.uniprot.org/uniprotkb/Q9VND0" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VND0", "url": "https://www.uniprot.org/uniprotkb/Q9VND0" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VND0", "url": "https://www.uniprot.org/uniprotkb/Q9VND0" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VND0", "url": "https://www.uniprot.org/uniprotkb/Q9VND0" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VND0", "url": "https://www.uniprot.org/uniprotkb/Q9VND0" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VND0", "url": "https://www.uniprot.org/uniprotkb/Q9VND0" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG10390", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG10390", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B5DF37-1", "protein_name": "TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L", "gene_name": "Taf6l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHSSTGAMSEREERRFVEIPRESVRLMAESTGLELSDEVAALLAEDVCYRLREATQNSSQFMKHTKRRKLTVEDFNRALRWSSVEAVCGYGSQEVLPLRPAREGELYFPEDREVNLVELALATNIPKGCAETAVRVHVSYLDGKGNLAPQGSVPSAVSSLTDDLLKYYQQVTRAVLGDDPQLMKVALQDLQTNSKIAALLPYFVYVVSGVKSVSHDLEQLHRLLQVARSLIRNPHLCLGPYVRSLVGSVLYCVLEPLAASINPLNDHWTLRDGAALLLSHIFWTHGDLVSGLYQQILLSLQKVLTDPVRPLCSHYGAVVGLHALGWKAVERVLYPHLPTYWTNLQAVLDDYSVSNAQVKADGHKVYGAILVAVERLLKMKAQAAEPNRGGLGGRGYRPAEDLPWDSLLLQESPPGGGSEPGFGSGLLLPSGVAGSEDPSSLTLADIYRELYSFFGDSLATRFGTGQPAPTAPRPPGDKKEPATTPDSVRKMPQLTASAVVSPQGDESPCGGTLAAANATSESRPLPRVHRARGAPRQQGPGAGTRDVFQKSRFAPRGAPHFRFIIAGRQAGRRCRGRLFQTAFPAPYGPSPASRYVQKLPMIGRTGRPARRWALSDYSLYLPL", "length": 623 }, "evidence": [ { "id": "SGD:S000003080", "url": "https://alliancegenome.org/gene/SGD:S000003080#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7FEV1-1", "protein_name": "TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L", "gene_name": "taf6l", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTEREERRFAEVPRESVKLMAESAGVELSEELAGLLAEDVCYRLREATQNSSQFMRHAKRRKLSVEDFNRALRWSNTETVCGYGAQDALPFRPLKEGELFYVEDREINLVELALATNIPKGCAETMVRVHVSYLDGKGNLEPQGTVPTAVQSLSEDLLKYYQQITRAILGEDPHLMKVALLDLQSNSKIAALLPYFVYVISGVKSVSHDLDQLNRLLHMVKSLVQNPYLYLGSYVRSLVSSVMYCILEPLAASINPLNDHWTLRDYAALLLSHIFWTHGDLVSGLYHQILLSLQKVLSDPVRPLCSHYGAVVGLHALGWKAVERVLYPHLPAYWANLQAVLDDYSVSNAQVKADGHKVYGAILVAVERLLKMKALSLTLAAEGGSAALSGSVTGAVGFRENSPGLSPPPEPLSEPPLGIASHLQAGGAGCPWEEWTPVSLPAMYCELYSFFGDSLAVRFSTDPPLAGAAPAGPSQPLEGRKETATAAPNLESTRKMPQLTASMNISPRQDGSPRTEPQPPSLAATVPGRSLARSSSSSSSVSRSRSSSSRPGRSSSQSRDIFPKARFPLPQAGPPAFSFIIGGRQMGRRCQGRRFQTSFSPTPPLTSLPPRAYAHKLPVIGRVSKPVRRWTSSHYSLHLPL", "length": 641 }, "evidence": [ { "id": "SGD:S000003080", "url": "https://alliancegenome.org/gene/SGD:S000003080#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P49847-1", "protein_name": "Transcription initiation factor TFIID subunit 6", "gene_name": "Taf6", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSGKPSKPSSPSSSMLYGSSISAESMKVIAESIGVGSLSDDAAKELAEDVSIKLKRIVQDAAKFMNHAKRQKLSVRDIDMSLKVRNVEPQYGFVAKDFIPFRFASGGGRELHFTEDKEIDLGEITSTNSVKIPLDLTLRSHWFVVEGVQPTVPENPPPLSKDSQLLDSVNPVIKMDQGLNKDAAGKPTTGKIHKLKNVETIHVKQLATHELSVEQQLYYKEITEACVGSDEPRRGEALQSLGSDPGLHEMLPRMCTFIAEGVKVNVVQNNLALLIYLMRMVRALLDNPSLFLEKYLHELIPSVMTCIVSKQLCMRPELDNHWALRDFASRLMAQICKNFNTLTNNLQTRVTRIFSKALQNDKTHLSSLYGSIAGLSELGGEVIKVFIIPRLKFISERIEPHLLGTSISNTDKTAAGHIRAMLQKCCPPILRQMRSAPDTAEDYKNDFGFLGPSLCQAVVKVRNAPASSIVTLSSNTINTAPITSAAQTATTIGRVSMPTTQRQGSPGVSSLPQIRAIQANQPAQKFVIVTQNSPQQGQAKVVRRGSSPHSVVLSAASNAASASNSNSSSSGSLLAAAQRSSDNVCVIAGSEAPAVDGITVQSFRAS", "length": 606 }, "evidence": [ { "id": "SGD:S000003080", "url": "https://alliancegenome.org/gene/SGD:S000003080#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P49848-1", "protein_name": "Transcription initiation factor TFIID subunit 6", "gene_name": "TAF6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEEKKLKLSNTVLPSESMKVVAESMGIAQIQEETCQLLTDEVSYRIKEIAQDALKFMHMGKRQKLTTSDIDYALKLKNVEPLYGFHAQEFIPFRFASGGGRELYFYEEKEVDLSDIINTPLPRVPLDVCLKAHWLSIEGCQPAIPENPPPAPKEQQKAEATEPLKSAKPGQEEDGPLKGKGQGATTADGKGKEKKAPPLLEGAPLRLKPRSIHELSVEQQLYYKEITEACVGSCEAKRAEALQSIATDPGLYQMLPRFSTFISEGVRVNVVQNNLALLIYLMRMVKALMDNPTLYLEKYVHELIPAVMTCIVSRQLCLRPDVDNHWALRDFAARLVAQICKHFSTTTNNIQSRITKTFTKSWVDEKTPWTTRYGSIAGLAELGHDVIKTLILPRLQQEGERIRSVLDGPVLSNIDRIGADHVQSLLLKHCAPVLAKLRPPPDNQDAYRAEFGSLGPLLCSQVVKARAQAALQAQQVNRTTLTITQPRPTLTLSQAPQPGPRTPGLLKVPGSIALPVQTLVSARAAAPPQPSPPPTKFIVMSSSSSAPSTQQVLSLSTSAPGSGSTTTSPVTTTVPSVQPIVKLVSTATTAPPSTAPSGPGSVQKYIVVSLPPTGEGKGGPTSHPSPVPPPASSPSPLSGSALCGGKQEAGDSPPPAPGTPKANGSQPNSGSPQPAP", "length": 677 }, "evidence": [ { "id": "SGD:S000003080", "url": "https://alliancegenome.org/gene/SGD:S000003080#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P53040-1", "protein_name": "SAGA complex/transcription factor TFIID complex subunit TAF6", "gene_name": "TAF6", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSTQQQSYTIWSPQDTVKDVAESLGLENINDDVLKALAMDVEYRILEIIEQAVKFKRHSKRDVLTTDDVSKALRVLNVEPLYGYYDGSEVNKAVSFSKVNTSGGQSVYYLDEEEVDFDRLINEPLPQVPRLPTFTTHWLAVEGVQPAIIQNPNLNDIRVSQPPFIRGAIVTALNDNSLQTPVTSTTASASVTDTGASQHLSNVKPGQNTEVKPLVKHVLSKELQIYFNKVISTLTAKSQADEAAQHMKQAALTSLRTDSGLHQLVPYFIQFIAEQITQNLSDLQLLTTILEMIYSLLSNTSIFLDPYIHSLMPSILTLLLAKKLGGSPKDDSPQEIHEFLERTNALRDFAASLLDYVLKKFPQAYKSLKPRVTRTLLKTFLDINRVFGTYYGCLKGVSVLEGESIRFFLGNLNNWARLVFNESGITLDNIEEHLNDDSNPTRTKFTKEETQILVDTVISALLVLKKDLPDLYEGKGEKVTDEDKEKLLERCGVTIGFHILKRDDAKELISAIFFGE", "length": 516 }, "evidence": [ { "id": "FB:FBgn0014342", "url": "https://alliancegenome.org/gene/FB:FBgn0014342#orthology", "database": "AGR" }, { "id": "SGD:S000003080", "url": "https://alliancegenome.org/gene/SGD:S000003080#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q62311-1", "protein_name": "Transcription initiation factor TFIID subunit 6", "gene_name": "Taf6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEEKKLKLSNTVLPSESMKVVAESMGIAQIQEETCQLLTDEVSYRIKEIAQDALKFMHMGKRQKLTTSDIDYALKLKNVEPLYGFHAQEFIPFRFASGGGRELYFYEEKEVDLSDIINTPLPRVPLDVCLKAHWLSIEGCQPAIPENPPPAPKEQQKAEATEPLKSAKPGQEEDGPLKGKGQGAAAADGKGKEKKAPPLLEGAPFRLKPRSIHELSVEQQLYYKEITEACVGSCEAKRAEALQSIATDPGLYQMLPRFSTFISEGVRVNVVQNNLALLIYLMRMVKALMDNPTLYLEKYVHELIPAVMTCIVSRQLCLRPDVDNHWALRDFAARLVAQICKHFSTTTNNIQSRITKTFTKSWVDEKTPWTTRYGSIAGLAELGHDVIKTLILPRLQQEGERIRSVLDGPVLSNIDRIGADHVQSLLLKHCAPVLAKLRPPPDNQDAYRGEFGSLGPLLCSHVVKARAQAALQAQQVNRTTLTITQPRPTLTLSQAPQPGPRTPGLLKVPGSIALPVQTLVSARAAAPPQPSPPPTKFIVMSSSSSASSTQQVLSLSTSAPGSGSTTTSPVTTTVPSVQPIVKLVSTATTAPPSTAPAGSGSVQKYIVVSLPPTGEGKGGPPSHPSPVPPSSSSPSPLGGSTLCGGKQEAGDSPPPAPGTPKANGSQPTGPGSPQPAL", "length": 678 }, "evidence": [ { "id": "SGD:S000003080", "url": "https://alliancegenome.org/gene/SGD:S000003080#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q63801-1", "protein_name": "Transcription initiation factor TFIID subunit 6", "gene_name": "Taf6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEEKKLKLSNTVLPSESMKVVAESMGIAQIQEETCQLLTDEVSYRIKEIAQDALKFMHMGKRQKLTTSDIDYALKLKNVEPLYGFHAQEFIPFRFASGGGRELYFYEEKEVDLSDIINTPLPRVPLDVCLKAHWLSIEGCQPAIPENPPPAPKEQQKAEATEPLKSAKPGQEEDGPLKGKGQGAAAADGKGKEKKAPPLLEGAPFRLKPRSIHELSVEQQLYYKEITEACVGSCEAKRAEALQSIATDPGLYQMLPRFSTFISEGVRVNVVQNNLALLIYLMRMVKALMDNPTLYLEKYVHELIPAVMTCIVSRQLCLRPDVDNHWALRDFAARLVAQICKHFSTTTNNIQSRITKTFTKSWVDEKTPWTTRYGSIAGLAELGHDVIKTLILPRLQQEGERIRSVLDGPVLSNIDRIGADHVQSLLLKHCAPVLAKLRPPPDNQDAYRGEFGSLGPLLCSHVVKARAQAALQAQQVNRTTLTITQPRPTLTLSQAPQPGPRTPGLLKVPGSIALPVQTLVSARAAAPPQPSPPPTKFIVMSSSSSASSTQQVLSLSTSAPGSGSTTTSPVTTTVPSVQPIVKLVSTATTAPPSTAPAGPGSVQKYIVVSLPPTGEGKGGPPSHPSPVPPSSSSPSPLGGSALCGGKQETGDSPPPAPGTPKANGSQPTGPSSPQPAL", "length": 678 }, "evidence": [ { "id": "SGD:S000003080", "url": "https://alliancegenome.org/gene/SGD:S000003080#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8R2K4-1", "protein_name": "TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L", "gene_name": "Taf6l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSEREERRFVEIPRESVRLMAESTGLELSDEVAALLAEDVCYRLREATQNSSQFMKHTKRRKLTVEDFNRALRWSSVEAVCGYGSQEALPLRPAREGDLYFPEDREVSLVELALATNIPKGCAETAVRVHVSYLDGKGNLAPQGSVPSAVSSLTDDLLKYYQQVTRAVLGDDPQLMKVALQDLQTNSKIAALLPYFVYVVSGVKSVSHDLEQLHRLLQVARSLIRNPHLCLGPYVRSLVGSVLYCVLEPLAASINPLNDHWTLRDGAALLLSHIFWTHGDLVSGLYQQILLSLQKVLTDPVRPLCSHYGAVVGLHALGWKAVERVLYPHLPTYWTNLQAVLDDYSVSNAQVKADGHKVYGAILVAVERLLKMKAQAAEPNRGGLGGRGYRPAEDLPWDSLLLQESPPGGSSETGFGSGLPPPSGVAGPEDPSSLTLADIYRELYSFFGDSLATRFGTGQPAPTAPRPPGDKKEPAAAPDSVRKMPQLTASAVVSPQGDESPCGGTLATATAASESRPLPRVHRARGAPRQQGPGAGTRDVFQKSRFAPRGAPHFRFIIAGRQAGRRCRGRLFQTAFPAPYGPSPASRYVQKLPMIGRTGRPARRWALSDYSLYLPL", "length": 616 }, "evidence": [ { "id": "SGD:S000003080", "url": "https://alliancegenome.org/gene/SGD:S000003080#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y6J9-1", "protein_name": "TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L", "gene_name": "TAF6L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSEREERRFVEIPRESVRLMAESTGLELSDEVAALLAEDVCYRLREATQNSSQFMKHTKRRKLTVEDFNRALRWSSVEAVCGYGSQEALPMRPAREGELYFPEDREVNLVELALATNIPKGCAETAVRVHVSYLDGKGNLAPQGSVPSAVSSLTDDLLKYYHQVTRAVLGDDPQLMKVALQDLQTNSKIGALLPYFVYVVSGVKSVSHDLEQLHRLLQVARSLFRNPHLCLGPYVRCLVGSVLYCVLEPLAASINPLNDHWTLRDGAALLLSHIFWTHGDLVSGLYQHILLSLQKILADPVRPLCCHYGAVVGLHALGWKAVERVLYPHLSTYWTNLQAVLDDYSVSNAQVKADGHKVYGAILVAVERLLKMKAQAAEPNRGGPGGRGCRRLDDLPWDSLLFQESSSGGGAEPSFGSGLPLPPGGAGPEDPSLSVTLADIYRELYAFFGDSLATRFGTGQPAPTAPRPPGDKKEPAAAPDSVRKMPQLTASAIVSPHGDESPRGSGGGGPASASGPAASESRPLPRVHRARGAPRQQGPGTGTRDVFQKSRFAPRGAPHFRFIIAGRQAGRRCRGRLFQTAFPAPYGPSPASRYVQKLPMIGRTSRPARRWALSDYSLYLPL", "length": 622 }, "evidence": [ { "id": "SGD:S000003080", "url": "https://alliancegenome.org/gene/SGD:S000003080#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "Q9VND0", "url": "https://www.uniprot.org/uniprotkb/Q9VND0" } ], "pmid": "" }, { "name": "RNA polymerase II general transcription initiation factor activity", "id": "GO:0016251", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016251", "evidence": [ { "database": "UniProtKB", "id": "Q9VND0", "url": "https://www.uniprot.org/uniprotkb/Q9VND0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q9VND0", "url": "https://www.uniprot.org/uniprotkb/Q9VND0" } ], "pmid": "" }, { "name": "male germ cell nucleus", "id": "GO:0001673", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001673", "evidence": [ { "database": "UniProtKB", "id": "Q9VND0", "url": "https://www.uniprot.org/uniprotkb/Q9VND0" } ], "pmid": "" }, { "name": "transcription factor TFIID complex", "id": "GO:0005669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005669", "evidence": [ { "database": "UniProtKB", "id": "Q9VND0", "url": "https://www.uniprot.org/uniprotkb/Q9VND0" } ], "pmid": "" }, { "name": "SAGA complex", "id": "GO:0000124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000124", "evidence": [ { "database": "UniProtKB", "id": "Q9VND0", "url": "https://www.uniprot.org/uniprotkb/Q9VND0" } ], "pmid": "" }, { "name": "SLIK (SAGA-like) complex", "id": "GO:0046695", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046695", "evidence": [ { "database": "UniProtKB", "id": "Q9VND0", "url": "https://www.uniprot.org/uniprotkb/Q9VND0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "Q9VND0", "url": "https://www.uniprot.org/uniprotkb/Q9VND0" } ], "pmid": "" }, { "name": "transcription initiation at RNA polymerase II promoter", "id": "GO:0006367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006367", "evidence": [ { "database": "UniProtKB", "id": "Q9VND0", "url": "https://www.uniprot.org/uniprotkb/Q9VND0" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "Q9VND0", "url": "https://www.uniprot.org/uniprotkb/Q9VND0" } ], "pmid": "" }, { "name": "spermatid differentiation", "id": "GO:0048515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048515", "evidence": [ { "database": "UniProtKB", "id": "Q9VND0", "url": "https://www.uniprot.org/uniprotkb/Q9VND0" } ], "pmid": "" }, { "name": "male meiosis I", "id": "GO:0007141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007141", "evidence": [ { "database": "UniProtKB", "id": "Q9VND0", "url": "https://www.uniprot.org/uniprotkb/Q9VND0" } ], "pmid": "" }, { "name": "RNA polymerase II preinitiation complex assembly", "id": "GO:0051123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051123", "evidence": [ { "database": "UniProtKB", "id": "Q9VND0", "url": "https://www.uniprot.org/uniprotkb/Q9VND0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 375, "end_pos": 377, "annotation": "n_glycosylation_sequon" }, { "start_pos": 8, "end_pos": 10, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VND0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VND0" }, { "id": "PF07571", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07571" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TAF6 C-terminal HEAT repeat", "eco_id": "ECO_0000259", "start_pos": 180, "end_pos": 361, "start_aa": "Tyr", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 375, "end_pos": 377 }, { "start_pos": 8, "end_pos": 10 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VND2" } ] }, { "name": "SNM1", "type": "synonym", "evidence": [ { "id": "NP_649548", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649548" }, { "id": "Q9VND2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VND2" } ] }, { "name": "Snm1", "type": "synonym", "evidence": [ { "id": "NP_649548", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649548" } ] }, { "name": "mus322", "type": "synonym", "evidence": [ { "id": "NP_649548", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649548" }, { "id": "Q9VND2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VND2" } ] } ], "protein_names": [ { "name": "CG10018-PA", "type": "synonym", "evidence": [ { "id": "NP_649548", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649548" } ] }, { "name": "Snm1-PA", "type": "synonym", "evidence": [ { "id": 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}, { "id": "PTHR23240", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23240", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23240:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23240:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07522", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07522", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12706", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12706", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q9VND2", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q9VND2", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_649548", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649548", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VND2", "url": "https://www.uniprot.org/uniprotkb/Q9VND2", "database": 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"tr|Q9VND2-1|Q9VND2_DROME Isoform 1 of Snm1 OS=Drosophila melanogaster OX=7227 GN=Snm1 PE=3 SV=1 CANONICAL=Q9VND2-1" }, "isoforms": [ { "isoform_ac": "Q9VND2-1", "url": "https://www.uniprot.org/uniprotkb/Q9VND2/entry#Q9VND2-1", "sequence": { "sequence": "MSNVGKIKIRSIADLQATVRVNVEPDPTPTIENRTPDKKRAGRTRAASTTKKVRPKTEACPIIASTAFKRSSKKTPLPGQMRIDSFFTSAVKNYKVKSSSSCRKVDPPLDKRKVSTKGRKRLFEESTTTSSAFTGKLDAKPSEKRVQPSRRAKGKENASLSEVHVIDLCSEDEQTIKRKPSAIASPCEKSSDVQATKFRTPETSMPEAKLSNSSLDLVEISPGPNKSPTNNFYRSSPAAITKESPLGKNSKKGTVRKQRKPKPCPPYKVVEGTSFCVDGFQFGEIEGVTHYFLTHFHADHYIGLTKKFCHPLYVSPISARLVRTFIKLDETHIHEIDVDQTLDVDGVQVTALEANHCPGALMFFFKLSSGECILHTGDFRASADMESLPIFWNHSNIDLLYLDTTYMNKNYDFCHQSESVDRAVDLVRAFLEKNAAKRILIVCGSYVIGKEKIWLALAKEFTMRVWTESNRSTAVRCLNWPDLDSVLTEDRSGANLHVIAMGKISYPSLVDYFTEFEDQYDMLLGIRPSGWEKNSKPSYGKRISTIGIEYSEHSSYKELERFVRFLKPKRVISTVPVGRDLYVTGEVPIRWYKYEGRASMLRTGFQPSISTFLATPKRAFAKFSADTEMFLSPVDENASKGSEDKKDDDRESVVPTNHVTIISDTPEECFQTDSKIPVKNEPLAPDTSPNSEIVAQLNAMESEIPYVEIDIKNETIAPDAVLIPRVPTEDTFQSTDCNVIGVQKSQAVVVSRLTSDASDDWLL", "length": 763, "header": "tr|Q9VND2-1|Q9VND2_DROME Isoform 1 of Snm1 OS=Drosophila melanogaster OX=7227 GN=Snm1 PE=3 SV=1 CANONICAL=Q9VND2-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 28, "start_aa": "Thr", "end_pos": 28, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr28", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VND2", "url": "https://www.uniprot.org/uniprotkb/Q9VND2" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VND2", "url": "https://www.uniprot.org/uniprotkb/Q9VND2" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VND2", "url": "https://www.uniprot.org/uniprotkb/Q9VND2" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VND2", "url": "https://www.uniprot.org/uniprotkb/Q9VND2" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VND2", "url": "https://www.uniprot.org/uniprotkb/Q9VND2" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VND2", "url": "https://www.uniprot.org/uniprotkb/Q9VND2" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VND2", "url": "https://www.uniprot.org/uniprotkb/Q9VND2" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VND2", "url": "https://www.uniprot.org/uniprotkb/Q9VND2" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VND2", "url": "https://www.uniprot.org/uniprotkb/Q9VND2" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VND2", "url": "https://www.uniprot.org/uniprotkb/Q9VND2" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VND2", "url": "https://www.uniprot.org/uniprotkb/Q9VND2" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG10018", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG10018", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3Z924-1", "protein_name": "DNA cross-link repair 1A protein", "gene_name": "Dclre1a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLEDAFWEEDIWEYKSKRKPKPVHPNSCSENISESVEKATDGKYQSKGKGNKKRTSENPGETKDHPVCLAETNSQISAGSSQNSSCRDDIQQSQSKETTPKKQCRTNRGKQATPKVRPLYDGHCPSCQMPFSSLLGQTPRWHVFECLDSPPISDTECPDGVLCSSTIPSHYKKYTHVLLAQSRDSKEPLSPSQALAGRFAAAQPDSCNLEERRSVLLKTEDSRKVLEDSLLMIQCLKTSQPPAETNRKSASSPRSQKSLVPQRAEFVKRDQLVGSGSPLAEVAFNCQSESGSTGLPLPENGCGDFEISYSPLHSDEETYNCDQELDDSQQELFFTQSSKDSSLEDVSATFENLHGPFPEEAEGIQPTAKTLAAQAGCSALSRGSTGNDSFQLISRTSGRLSGEDPSDTDAAFLLLSPAPSAVGGATPNCQTTKAKPEKFHSLASRHQQQKTETSAAGSHTSLPLLLSAMSKPLEKEGGERLPLHPTQSQRRGLWSKGSGAPGANCACSNTQRPSSAPLNKSLSTAPSSPKGSASQPSKKVMKQMDIGVFFGLPPKTQDTSPRERASEGPKASPVVSPSEKRPRLCKRKAQSSLSDLEFDAKNLNESQHSMELSGERAQHRRKRHKKSNSPQEGTYQGRSGHLTNNPELGAVSLRRSKAFARRTPSRTQRGAVNISESSGGGESRRTCPFYKRIPGTGFTVDAFQYGEIEGCTAYFLTHFHSDHYAGLSKDFTRPIYCSEITGSLLKKKLRVQEQYIHQLPMDTECIVDGVKVVLLDANHCPGATMILFQLPNGAVTLHTGDFRADPSMERSLLASRKVHTLFLDTTYCSPEYTFPSQQEAIQFAINTAFEAVTLNPRALIVCGTYCIGKEKVFLAIADVLGSKVGMSQEKYKTLQCLNIPEVSSLITTDMCNSLVHLLPMMQINFKGLQNHLKKCGGKFDQILAFRPTGWTHSNNITSIADITPQTKGNIAIYGIPYSEHSSYLEMKRFVQWLKPQKIIPTVNVGTFQSRNTMEKYFKEWRLEAGY", "length": 1026 }, "evidence": [ { "id": "RGD:1306156", "url": "https://alliancegenome.org/gene/RGD:1306156#orthology", "database": "AGR" }, { "id": "MGI:1930042", "url": "https://alliancegenome.org/gene/MGI:1930042#orthology", "database": "AGR" }, { "id": "HGNC:17660", "url": "https://alliancegenome.org/gene/HGNC:17660#orthology", "database": "AGR" }, { "id": "FB:FBgn0037338", "url": "https://alliancegenome.org/gene/FB:FBgn0037338#orthology", "database": "AGR" }, { "id": "SGD:S000004745", "url": "https://alliancegenome.org/gene/SGD:S000004745#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7F457-1", "protein_name": "DNA cross-link repair 1A protein", "gene_name": "dclre1a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSQSGSESDIWDYKPLKKNKKRSCKSQGSREHVTKRKKESTVQKTVKSAEKHTDLDHQIGSNAPNNTVNSGSEDVNHGTVSRDVPNADSQSGRGFCPVCQMPFSILVVQSQQWHVAECLDTAADNCKECPDGLQCMSTIPNHYKRYNHSQLAQSRAQNDSVQAISDFSLNSVNNGASTSVKESSVDSAVNVSASSSQSSSPGDRLKGTPTKSNALLLLRSPNTEDIKKKKGWSPSVKRSQSQISSQEAKAKISAPGEVRCVDSAVQTQPNEVKKELFECKDDDDYISCSPLSELPEVDEEHRVEKSNNDRHFYSTALQEDDDSLNLFSDEDDDLFFDVIDQYEEHGPDKSSLDTCEKQQTSLAPESHLTASSSTGVSFHHCSTNNNSSNSQLQSPQSLVLEHLRDRISTPTHVKSLTSSFEEVNFTQTNQESFSNQADLSATQSMAPRRTQIKAGPSGLKQTDIGVFFGLKPLHEKKAGKEVKPLVREADLQKSRRVRVSEAQGEDGKRQGRWRGKSKAPSEGSGVSPAVEDSVALPTQTEGKRGGRAEGRKRWNRGKATDGDPKEPKRCPFYKKIPGTGFAVDAFQYGVVEGVTAYFLTHFHSDHYGGLKKDSAVPIYCNKVTSNLVKSKLKVDEQYIHVLPMNTECIVQGVKVTLLDANHCPGAAMLLFVLPDGQTVLHTGDFRADPSMERYPELQGLRIQTLYLDTTYCSPEYTFPTQQEVVTFAVNTAFERVTLNPRTLVVCGTYSVGKEKVFLAVSEVLSSKVCLSKDKYNTMCCLESEDIGQRITTNWQSAQVHVLPMMQINFKNLQTHLKKFSKKYDQLVAFKPTGWTFNQTVGVDDILPQTQGNISIYGIPYSEHSSFLELKRFVQWLRPKKIIPTVNVGSWRSRKAMEGFFHEWMTEPRNLSSTPCTLRSSSCGTRQ", "length": 926 }, "evidence": [ { "id": "MGI:1930042", "url": "https://alliancegenome.org/gene/MGI:1930042#orthology", "database": "AGR" }, { "id": "HGNC:17660", "url": "https://alliancegenome.org/gene/HGNC:17660#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P30620-1", "protein_name": "DNA cross-link repair protein PSO2/SNM1", "gene_name": "PSO2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSRKSIVQIRRSEVKRKRSSTASSTSEGKTLHKNTHTSSKRQRTLTEFNIPTSSNLPVRSSSYSFSRFSCSTSNKNTEPVIINDDDHNSICLEDTAKVEITIDTDEEELVSLHDNEVSAIENRTEDRIVTELEEQVNVKVSTEVIQCPICLENLSHLELYERETHCDTCIGSDPSNMGTPKKNIRSFISNPSSPAKTKRDIATSKKPTRVKLVLPSFKIIKFNNGHEIVVDGFNYKASETISQYFLSHFHSDHYIGLKKSWNNPDENPIKKTLYCSKITAILVNLKFKIPMDEIQILPMNKRFWITDTISVVTLDANHCPGAIIMLFQEFLANSYDKPIRQILHTGDFRSNAKMIETIQKWLAETANETIDQVYLDTTYMTMGYNFPSQHSVCETVADFTLRLIKHGKNKTFGDSQRNLFHFQRKKTLTTHRYRVLFLVGTYTIGKEKLAIKICEFLKTKLFVMPNSVKFSMMLTVLQNNENQNDMWDESLLTSNLHESSVHLVPIRVLKSQETIEAYLKSLKELETDYVKDIEDVVGFIPTGWSHNFGLKYQKKNDDDENEMSGNTEYCLELMKNDRDNDDENGFEISSILRQYKKYNKFQVFNVPYSEHSSFNDLVKFGCKLKCSEVIPTVNLNNLWKVRYMTNWFQCWENVRKTRAAK", "length": 661 }, "evidence": [ { "id": "RGD:1306156", "url": "https://alliancegenome.org/gene/RGD:1306156#orthology", "database": "AGR" }, { "id": "MGI:1930042", "url": "https://alliancegenome.org/gene/MGI:1930042#orthology", "database": "AGR" }, { "id": "HGNC:17660", "url": "https://alliancegenome.org/gene/HGNC:17660#orthology", "database": "AGR" }, { "id": "FB:FBgn0037338", "url": "https://alliancegenome.org/gene/FB:FBgn0037338#orthology", "database": "AGR" }, { "id": "SGD:S000004745", "url": "https://alliancegenome.org/gene/SGD:S000004745#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q6PJP8-1", "protein_name": "DNA cross-link repair 1A protein", "gene_name": "DCLRE1A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLEDISEEDIWEYKSKRKPKRVDPNNGSKNILKSVEKATDGKYQSKRSRNRKRAAEAKEVKDHEVPLGNAGCQTSVASSQNSSCGDGIQQTQDKETTPGKLCRTQKSQHVSPKIRPVYDGYCPNCQMPFSSLIGQTPRWHVFECLDSPPRSETECPDGLLCTSTIPFHYKRYTHFLLAQSRAGDHPFSSPSPASGGSFSETKSGVLCSLEERWSSYQNQTDNSVSNDPLLMTQYFKKSPSLTEASEKISTHIQTSQQALQFTDFVENDKLVGVALRLANNSEHINLPLPENDFSDCEISYSPLQSDEDTHDIDEKPDDSQEQLFFTESSKDGSLEEDDDSCGFFKKRHGPLLKDQDESCPKVNSFLTRDKYDEGLYRFNSLNDLSQPISQNNESTLPYDLACTGGDFVLFPPALAGKLAASVHQATKAKPDEPEFHSAQSNKQKQVIEESSVYNQVSLPLVKSLMLKPFESQVEGYLSSQPTQNTIRKLSSENLNAKNNTNSACFCRKALEGVPVGKATILNTENLSSTPAPKYLKILPSGLKYNARHPSTKVMKQMDIGVYFGLPPKRKEEKLLGESALEGINLNPVPSPNQKRSSQCKRKAEKSLSDLEFDASTLHESQLSVELSSERSQRQKKRCRKSNSLQEGACQKRSDHLINTESEAVNLSKVKVFTKSAHGGLQRGNKKIPESSNVGGSRKKTCPFYKKIPGTGFTVDAFQYGVVEGCTAYFLTHFHSDHYAGLSKHFTFPVYCSEITGNLLKNKLHVQEQYIHPLPLDTECIVNGVKVVLLDANHCPGAVMILFYLPNGTVILHTGDFRADPSMERSLLADQKVHMLYLDTTYCSPEYTFPSQQEVIRFAINTAFEAVTLNPHALVVCGTYSIGKEKVFLAIADVLGSKVGMSQEKYKTLQCLNIPEINSLITTDMCSSLVHLLPMMQINFKGLQSHLKKCGGKYNQILAFRPTGWTHSNKFTRIADVIPQTKGNISIYGIPYSEHSSYLEMKRFVQWLKPQKIIPTVNVGTWKSRSTMEKYFREWKLEAGY", "length": 1040 }, "evidence": [ { "id": "RGD:1306156", "url": "https://alliancegenome.org/gene/RGD:1306156#orthology", "database": "AGR" }, { "id": "MGI:1930042", "url": "https://alliancegenome.org/gene/MGI:1930042#orthology", "database": "AGR" }, { "id": "HGNC:17660", "url": "https://alliancegenome.org/gene/HGNC:17660#orthology", "database": "AGR" }, { "id": "FB:FBgn0037338", "url": "https://alliancegenome.org/gene/FB:FBgn0037338#orthology", "database": "AGR" }, { "id": "SGD:S000004745", "url": "https://alliancegenome.org/gene/SGD:S000004745#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JIC3-1", "protein_name": "DNA cross-link repair 1A protein", "gene_name": "Dclre1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLEDTWEEEIWEYKSKRKPKPVHPNNCSENISESVEKSTDGKHQSKGNEKRTSENPGKTKDHKVCLAETDSQISAGSSQSSSCRDESQQSQNKETTPKKQHRTRRGKQVTPKVRPVYDGYCPSCQMPFSSLLGQTPQWHVFECLDSPPISDTECPEGLLCTSTIPSHYKKYTHILLAQSRDSKEPLGSPSDALAGLFAAAAPGSPCNLEERRSMTLKTENLRKVSDHSLLMMQYLETSQPSAEINRKNVSSPCSQTSPVPQCAEFVKRDQLVGGGSPLAEVALNSQSKSGSMGLPLPENDTDSCEISYSPLHSDEETYDIDQELDDSQQELFFTQSSKDSSLEEDGSAIFENLHGPSPKEAEGIRPTAKSLVAQARCSAPSEGSTLSDSFLLLSYTSNRLSQEDLPHTDAAFHLLSPALAVGGAASNYQTSKAKLDEPEKFLSLASSHQQQKIETSAVGNQTSLPLLTRARSKPLEKEGGKCLPLHPTQSQTRGSPRKGLGAPGANCACRNAQKRSSMPLDKPLGTSPSSPKCSPSQPSKKVMKQMDIGVFFGLPPKRQETSLRESASEGPNVSPVVSPNQKRPRLCKRKAQSSLSDLEFDAKNLNESQHSVGLSGEKRQHRRKRHKTSNSPREGPCQRRSGHLMNNPELGPVSLSKAFVRRTRGRTQRGNMNISESSGAGEVRRTCPFYKRIPGTGFTVDAFQYGEIEGCTAYFLTHFHSDHYAGLSKDFTRPVYCSEITGNLLKKKLRVQEQYIRQLPMDTECVVDSVKVVLLDANHCPGATMILFQLPNGAVILHTGDFRADPSMERSRLAGRKVHTLFLDTTYCSPEYTFPSQQEVIQFAINTAFEAVTLNPRALVVCGTYCIGKEKVFLAIADVLGSKVGMSQEKYKTLQCLNIPEVSSLITTDMCDSLVHLLPMMQINFKGLQSHLKKCGGKYDQILAFRPTGWTHSNNITSTADIIPQTRGNISIYGIPYSEHSSYLEMKRFVQWLKPQKIIPTVNVGSFRSRNTMEKYFKEWRLEAGY", "length": 1026 }, "evidence": [ { "id": "RGD:1306156", "url": "https://alliancegenome.org/gene/RGD:1306156#orthology", "database": "AGR" }, { "id": "MGI:1930042", "url": "https://alliancegenome.org/gene/MGI:1930042#orthology", "database": "AGR" }, { "id": "HGNC:17660", "url": "https://alliancegenome.org/gene/HGNC:17660#orthology", "database": "AGR" }, { "id": "FB:FBgn0037338", "url": "https://alliancegenome.org/gene/FB:FBgn0037338#orthology", "database": "AGR" }, { "id": "SGD:S000004745", "url": "https://alliancegenome.org/gene/SGD:S000004745#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VND2", "url": "https://www.uniprot.org/uniprotkb/Q9VND2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "damaged DNA binding", "id": "GO:0003684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003684", "evidence": [ { "database": "UniProtKB", "id": "Q9VND2", "url": "https://www.uniprot.org/uniprotkb/Q9VND2" } ], "pmid": "" }, { "name": "5'-3' DNA exonuclease activity", "id": "GO:0035312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035312", "evidence": [ { "database": "UniProtKB", "id": "Q9VND2", "url": "https://www.uniprot.org/uniprotkb/Q9VND2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "double-strand break repair via nonhomologous end joining", "id": "GO:0006303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006303", "evidence": [ { "database": "UniProtKB", "id": "Q9VND2", "url": "https://www.uniprot.org/uniprotkb/Q9VND2" } ], "pmid": "" }, { "name": "interstrand cross-link repair", "id": "GO:0036297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036297", "evidence": [ { "database": "UniProtKB", "id": "Q9VND2", "url": "https://www.uniprot.org/uniprotkb/Q9VND2" } ], "pmid": "" }, { "name": "RNA 3'-end processing", "id": "GO:0031123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031123", "evidence": [ { "database": "UniProtKB", "id": "Q9VND2", "url": "https://www.uniprot.org/uniprotkb/Q9VND2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 157, "end_pos": 159, "annotation": "n_glycosylation_sequon" }, { "start_pos": 212, "end_pos": 214, "annotation": "n_glycosylation_sequon" }, { "start_pos": 225, "end_pos": 227, "annotation": "n_glycosylation_sequon" }, { "start_pos": 33, "end_pos": 35, "annotation": "n_glycosylation_sequon" }, { "start_pos": 393, "end_pos": 395, "annotation": "n_glycosylation_sequon" }, { "start_pos": 470, "end_pos": 472, "annotation": "n_glycosylation_sequon" }, { "start_pos": 637, "end_pos": 639, "annotation": "n_glycosylation_sequon" }, { "start_pos": 713, "end_pos": 715, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VND2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VND2" }, { "id": "SM00849", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00849" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Metallo-beta-lactamase", "eco_id": "ECO_0000259", "start_pos": 263, "end_pos": 445, "start_aa": "Pro", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 28 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 157, "end_pos": 159 }, { "start_pos": 212, "end_pos": 214 }, { "start_pos": 225, "end_pos": 227 }, { "start_pos": 33, "end_pos": 35 }, { "start_pos": 393, "end_pos": 395 }, { "start_pos": 470, "end_pos": 472 }, { "start_pos": 637, "end_pos": 639 }, { "start_pos": 713, "end_pos": 715 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { 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Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh 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"Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VND4", "url": "https://www.uniprot.org/uniprotkb/Q9VND4" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VND4", "url": "https://www.uniprot.org/uniprotkb/Q9VND4" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VND4", "url": "https://www.uniprot.org/uniprotkb/Q9VND4" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VND4", "url": "https://www.uniprot.org/uniprotkb/Q9VND4" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VND4", "url": "https://www.uniprot.org/uniprotkb/Q9VND4" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VND4", "url": "https://www.uniprot.org/uniprotkb/Q9VND4" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VND4", "url": "https://www.uniprot.org/uniprotkb/Q9VND4" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VND4", "url": "https://www.uniprot.org/uniprotkb/Q9VND4" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF23381", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23381", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-159231", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-159231", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-73856", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-73856", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-77595", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-77595", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-9770562", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9770562", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_730982", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_730982", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VNG2", "url": "https://www.uniprot.org/uniprotkb/Q9VNG2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VNG2-1", "url": "https://www.uniprot.org/uniprotkb/Q9VNG2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDVSQPPPQLLTAPSALATNFTSLPPPNMGGQHYRHYHPHHGSNKHGYNQFKPFMPGGFQRPFGMSQDDFDGKRLRKSVMRKTVDYNASIIKALENRLYQRDYRDRLALQPDSIYVPHMLPPSAYLDNPSNAVTTRFVKTATNKMRCPIFTLAWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDISVRTMVWSHNDSWMVTGDHGGYVKYWQSNMNNVKMYQAHKEAIRGISFSPTDSKFVSGSDDGTLRIWDFMRCQEERVLRGHGADVKCVHWHPQKGMIVSGSKDNQQPIKIWDPKSGIALATLHAHKSTVMDLKWNDNGNWLVTASRDHLLKLFDIRNLREEVQVFRGHKKEASSVSWHPIHEGLFCSGGSDGSILFWNVGTDKEIGCVETAHDSIVWTLAWHPLGHILCSGSNDHTIKFWTRNRPGDLMRDKYNLNTLPASLAALDECEYDDAIIPGMGPEDRVEFTESLTADKGFIPGLDLDPSKAINDRDREKKVPYSKPIPRNFQVNWAGPRRADDPSVLSIHEELAAREAKDTTNGLNHQQISENTMEGILASGMLNGLDPQTIVGVLVYNRFIRVHPDSRLMAAIRQGAEFLNKYIDAGKLEELNDVVPVRDRSRSVSPTVEARGEMVSPPTKKSRFEPRQHNAQLVCVRELMQCKKPFLQSLVAAKAQQPNTEFVDEPPLEQRDRDREREGDRDRERERARERERDQSGGRPNPWASNAPWSNNGNPGGNGNGSNGFSNNGAESFNDRDRGGGGQRRRRGINNSGPGNGGGSGGGGGGGSGRNRGRNNNRRY", "length": 807, "header": "tr|Q9VNG2-1|Q9VNG2_DROME Isoform 1 of WD repeat domain 33, isoform A OS=Drosophila melanogaster OX=7227 GN=Wdr33 PE=1 SV=2 CANONICAL=Q9VNG2-1" }, "isoforms": [ { "isoform_ac": "Q9VNG2-1", "url": "https://www.uniprot.org/uniprotkb/Q9VNG2/entry#Q9VNG2-1", "sequence": { "sequence": "MDVSQPPPQLLTAPSALATNFTSLPPPNMGGQHYRHYHPHHGSNKHGYNQFKPFMPGGFQRPFGMSQDDFDGKRLRKSVMRKTVDYNASIIKALENRLYQRDYRDRLALQPDSIYVPHMLPPSAYLDNPSNAVTTRFVKTATNKMRCPIFTLAWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDISVRTMVWSHNDSWMVTGDHGGYVKYWQSNMNNVKMYQAHKEAIRGISFSPTDSKFVSGSDDGTLRIWDFMRCQEERVLRGHGADVKCVHWHPQKGMIVSGSKDNQQPIKIWDPKSGIALATLHAHKSTVMDLKWNDNGNWLVTASRDHLLKLFDIRNLREEVQVFRGHKKEASSVSWHPIHEGLFCSGGSDGSILFWNVGTDKEIGCVETAHDSIVWTLAWHPLGHILCSGSNDHTIKFWTRNRPGDLMRDKYNLNTLPASLAALDECEYDDAIIPGMGPEDRVEFTESLTADKGFIPGLDLDPSKAINDRDREKKVPYSKPIPRNFQVNWAGPRRADDPSVLSIHEELAAREAKDTTNGLNHQQISENTMEGILASGMLNGLDPQTIVGVLVYNRFIRVHPDSRLMAAIRQGAEFLNKYIDAGKLEELNDVVPVRDRSRSVSPTVEARGEMVSPPTKKSRFEPRQHNAQLVCVRELMQCKKPFLQSLVAAKAQQPNTEFVDEPPLEQRDRDREREGDRDRERERARERERDQSGGRPNPWASNAPWSNNGNPGGNGNGSNGFSNNGAESFNDRDRGGGGQRRRRGINNSGPGNGGGSGGGGGGGSGRNRGRNNNRRY", "length": 807, "header": "tr|Q9VNG2-1|Q9VNG2_DROME Isoform 1 of WD repeat domain 33, isoform A OS=Drosophila melanogaster OX=7227 GN=Wdr33 PE=1 SV=2 CANONICAL=Q9VNG2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VNG2", "url": "https://www.uniprot.org/uniprotkb/Q9VNG2" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VNG2", "url": "https://www.uniprot.org/uniprotkb/Q9VNG2" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VNG2", "url": "https://www.uniprot.org/uniprotkb/Q9VNG2" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VNG2", "url": "https://www.uniprot.org/uniprotkb/Q9VNG2" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VNG2", "url": "https://www.uniprot.org/uniprotkb/Q9VNG2" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VNG2", "url": "https://www.uniprot.org/uniprotkb/Q9VNG2" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VNG2", "url": "https://www.uniprot.org/uniprotkb/Q9VNG2" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VNG2", "url": "https://www.uniprot.org/uniprotkb/Q9VNG2" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VNG2", "url": "https://www.uniprot.org/uniprotkb/Q9VNG2" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VNG2", "url": "https://www.uniprot.org/uniprotkb/Q9VNG2" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VNG2", "url": "https://www.uniprot.org/uniprotkb/Q9VNG2" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG1109", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG1109", "resource": "KEGG Pathway" }, { "id": "R-DME-159231", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-159231", "resource": "Reactome", "description": "Transport of Mature mRNA Derived from an Intronless Transcript" }, { "id": "R-DME-73856", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-73856", "resource": "Reactome", "description": "RNA Polymerase II Transcription Termination" }, { "id": "R-DME-77595", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-77595", "resource": "Reactome", "description": "Processing of Intronless Pre-mRNAs" }, { "id": "R-DME-9770562", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9770562", "resource": "Reactome", "description": "mRNA Polyadenylation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0M1Z4-1", "protein_name": "pre-mRNA 3' end processing protein WDR33", "gene_name": "Wdr33", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATEIGSPPRFFHMPRFQHQAPRQLFYKRPDFAQQQAMQQLTFDGKRMRKAVNRKTIDYNPSVIKYLENRIWQRDQRDMRAIQPDAGYYNDLVPPIGMLNNPMNAVTTKFVRTSTNKVKCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERILRGHGADVKCVDWHPTKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKNTVMEVKLNLNGNWLLTASRDHLCKLFDIRNLKEELQVFRGHKKEATAVAWHPVHEGLFASGGSDGSLLFWHVGVEKEVGGMEMAHEGMIWSLAWHPLGHILCSGSNDHTSKFWTRNRPGDKMRDRYNLNLLPGMSEDGVEYDDLEPNSLAVIPGMGIPEQLKLAMEQEQMGKDESNDIEMTIPGLDWGMEEVMQKDQKKVPQKKVPYAKPIPAQFQQAWMQNKVPIPAPNEVLNDRKEDIKLEEKKKTQAEIEQEMATLQYTNPQLLEQLKIERLAQKQADQIQPPPSSGTPLLGPQPFSGQGPMSQIPQGFQQPHPSQQMPLVAQMGPPGPQGQFRAPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPAPQGHMGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPTSQGIQGPLMGLNPRGMQGPPGPRENQGPAPQGIMIGHPPQEMRGPHPPSGLLGHGPQEMRGPQEMRGMQGPPPQGSMLGPPQELRGPSGSQGQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKAPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKGTKGRRERHASGLPSPPGLVATTTTSPFVVVTLEALPTITWAPCQRGGMSRAVVLSMVLTGDLSGVARTAGVLLTGVALTLISLMTSADQMTSILTSALATGYGNSRDEEDPYHKKKSGGEGALDLPFHLITGSSMRGTAGVQPEALQGHGKAADLETNDSPGILMTHDFEGAEKKALEEVLPQDTKAVLLQEEGTTFLVLMTLVQKRFSMLLMKQPEDEISEVEAVAPLEGDPGSAYSPLLMSFLALKEDGSQTPGMETESPDQVMNTFVMLPVLIIPLTMAIHQLAESAPLLSKAWTWPPYHPGSAPGMMGRALLNTERWRPKEAPRRTEEAKAEGAQDLPREFQNPGVPALWTETIMMDTTEMNLLVALQAAAHLLEGAGVAVTGVEGVT", "length": 1343 }, "evidence": [ { "id": "RGD:1309230", "url": "https://alliancegenome.org/gene/RGD:1309230#orthology", "database": "AGR" }, { "id": "MGI:1921570", "url": "https://alliancegenome.org/gene/MGI:1921570#orthology", "database": "AGR" }, { "id": "HGNC:25651", "url": "https://alliancegenome.org/gene/HGNC:25651#orthology", "database": "AGR" }, { "id": "FB:FBgn0046222", "url": "https://alliancegenome.org/gene/FB:FBgn0046222#orthology", "database": "AGR" }, { "id": "SGD:S000005261", "url": "https://alliancegenome.org/gene/SGD:S000005261#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P42841-1", "protein_name": "Polyadenylation factor subunit 2", "gene_name": "PFS2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDGHNQNQYQNQNQIQQSQQPPLKKYVTQRRSVDVSSPYINLYYNRRHGLPNLVVEPETSYTIDIMPPNAYRGRDRVINLPSKFTHLSSNKVKHVIPAIQWTPEGRRLVVATYSGEFSLWNASSFTFETLMQAHDSAVTTMKYSHDSDWMISGDADGMIKIWQPNFSMVKEIDAAHTESIRDMAFSSNDSKFVTCSDDNILKIWNFSNGKQERVLSGHHWDVKSCDWHPEMGLIASASKDNLVKLWDPRSGNCISSILKFKHTVLKTRFQPTKGNLLMAISKDKSCRVFDIRYSMKELMCVRDETDYMTLEWHPINESMFTLACYDGSLKHFDLLQNLNEPILTIPYAHDKCITSLSYNPVGHIFATAAKDRTIRFWTRARPIDPNAYDDPTYNNKKINGWFFGINNDINAVREKSEFGAAPPPPATLEPHALPNMNGFINKKPRQEIPGIDSNIKSSTLPGLSI", "length": 465 }, "evidence": [ { "id": "RGD:1309230", "url": "https://alliancegenome.org/gene/RGD:1309230#orthology", "database": "AGR" }, { "id": "MGI:1921570", "url": "https://alliancegenome.org/gene/MGI:1921570#orthology", "database": "AGR" }, { "id": "HGNC:25651", "url": "https://alliancegenome.org/gene/HGNC:25651#orthology", "database": "AGR" }, { "id": "FB:FBgn0046222", "url": "https://alliancegenome.org/gene/FB:FBgn0046222#orthology", "database": "AGR" }, { "id": "SGD:S000005261", "url": "https://alliancegenome.org/gene/SGD:S000005261#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q8K4P0-1", "protein_name": "pre-mRNA 3' end processing protein WDR33", "gene_name": "Wdr33", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATEIGSPPRFFHMPRFQHQAPRQLFYKRPDFAQQQAMQQLTFDGKRMRKAVNRKTIDYNPSVIKYLENRIWQRDQRDMRAIQPDAGYYNDLVPPIGMLNNPMNAVTTKFVRTSTNKVKCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERILRGHGADVKCVDWHPTKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKNTVMEVKLNLNGNWLLTASRDHLCKLFDIRNLKEELQVFRGHKKEATAVAWHPVHEGLFASGGSDGSLLFWHVGVEKEVGGMEMAHEGMIWSLAWHPLGHILCSGSNDHTSKFWTRNRPGDKMRDRYNLNLLPGMSEDGVEYDDLEPNSLAVIPGMGIPEQLKLAMEQEQMGKDESSEIEMTIPGLDWGMEEVMQKDQKKVPQKKVPYAKPIPAQFQQAWMQNKVPIPAPNEVLNDRKEDIKLEEKKKTQAEIEQEMATLQYTNPQLLEQLKIERLAQKQADQIQPPPSSGTPLLGPQPFSGQGPISQIPQGFQQPHPSQQMPLVPQMGPPGPQGQFRAPGPQGQMGPQGPPMHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPASQGHMGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPASQGIQGPLMGLNPRGMQGPPGPRENQGPAPQGLMIGHPPQEMRGPHPPSGLLGHGPQEMRGPQEMRGMQGPPPQGSMLGPPQELRGPSGSQGQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKAPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKGDTRGPPNHHLGPMSERRHEQSGGPEHGPDRGPFRGGQDCRGPPDRRGSHPDFPDDFRPDDFHPDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPPFPPDHREFNEGDGRGAARGPPGAWEGRRPGDDRFPRDPDDPRFRGRREESFRRGAPPRHEGRAPPRGRDNFPGPDDFGPEEGFDASDEAARGRDLRGRGRGTPRGGSRKCLLPTPDEFPRFEGGRKPDSWDGNREPGPGHEHFRDAPRPDHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGSGTSEHREMEAQGGPSEDRGSKGRGGPGPSQRVPKSGRSSSLDGDHHDGYHRDEPFGGPPGSSSSSRGARSGSNWGRGSNMNSGPPRRGTSRGSGRGR", "length": 1330 }, "evidence": [ { "id": "RGD:1309230", "url": "https://alliancegenome.org/gene/RGD:1309230#orthology", "database": "AGR" }, { "id": "MGI:1921570", "url": "https://alliancegenome.org/gene/MGI:1921570#orthology", "database": "AGR" }, { "id": "HGNC:25651", "url": "https://alliancegenome.org/gene/HGNC:25651#orthology", "database": "AGR" }, { "id": "FB:FBgn0046222", "url": "https://alliancegenome.org/gene/FB:FBgn0046222#orthology", "database": "AGR" }, { "id": "SGD:S000005261", "url": "https://alliancegenome.org/gene/SGD:S000005261#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9C0J8-1", "protein_name": "pre-mRNA 3' end processing protein WDR33", "gene_name": "WDR33", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATEIGSPPRFFHMPRFQHQAPRQLFYKRPDFAQQQAMQQLTFDGKRMRKAVNRKTIDYNPSVIKYLENRIWQRDQRDMRAIQPDAGYYNDLVPPIGMLNNPMNAVTTKFVRTSTNKVKCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERILRGHGADVKCVDWHPTKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKNTVMEVKLNLNGNWLLTASRDHLCKLFDIRNLKEELQVFRGHKKEATAVAWHPVHEGLFASGGSDGSLLFWHVGVEKEVGGMEMAHEGMIWSLAWHPLGHILCSGSNDHTSKFWTRNRPGDKMRDRYNLNLLPGMSEDGVEYDDLEPNSLAVIPGMGIPEQLKLAMEQEQMGKDESNEIEMTIPGLDWGMEEVMQKDQKKVPQKKVPYAKPIPAQFQQAWMQNKVPIPAPNEVLNDRKEDIKLEEKKKTQAEIEQEMATLQYTNPQLLEQLKIERLAQKQVEQIQPPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGPEHGPERGPFRGGQDCRGPPDRRGPHPDFPDDFSRPDDFHPDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPPFPPDHREFSEGDGRGAARGPPGAWEGRRPGDERFPRDPEDPRFRGRREESFRRGAPPRHEGRAPPRGRDGFPGPEDFGPEENFDASEEAARGRDLRGRGRGTPRGGRKGLLPTPDEFPRFEGGRKPDSWDGNREPGPGHEHFRDTPRPDHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGKGRGGPGPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGSGTPSRGGRSGSNWGRGSNMNSGPPRRGASRGGGRGR", "length": 1336 }, "evidence": [ { "id": "RGD:1309230", "url": "https://alliancegenome.org/gene/RGD:1309230#orthology", "database": "AGR" }, { "id": "MGI:1921570", "url": "https://alliancegenome.org/gene/MGI:1921570#orthology", "database": "AGR" }, { "id": "HGNC:25651", "url": "https://alliancegenome.org/gene/HGNC:25651#orthology", "database": "AGR" }, { "id": "FB:FBgn0046222", "url": "https://alliancegenome.org/gene/FB:FBgn0046222#orthology", "database": "AGR" }, { "id": "SGD:S000005261", "url": "https://alliancegenome.org/gene/SGD:S000005261#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mRNA cleavage and polyadenylation specificity factor complex", "id": "GO:0005847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005847", "evidence": [ { "database": "UniProtKB", "id": "Q9VNG2", "url": "https://www.uniprot.org/uniprotkb/Q9VNG2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mRNA 3'-end processing", "id": "GO:0031124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031124", "evidence": [ { "database": "UniProtKB", "id": "Q9VNG2", "url": "https://www.uniprot.org/uniprotkb/Q9VNG2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 20, "end_pos": 22, "annotation": "n_glycosylation_sequon" }, { "start_pos": 747, "end_pos": 749, "annotation": "n_glycosylation_sequon" }, { "start_pos": 777, "end_pos": 779, "annotation": "n_glycosylation_sequon" }, { "start_pos": 87, "end_pos": 89, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VNG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VNG2" }, { "id": "PF23381", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23381" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "IFT122/SMU1 beta-propeller", "eco_id": "ECO_0000259", "start_pos": 212, "end_pos": 432, "start_aa": "Val", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 199, "end_pos": 201 }, { "start_pos": 20, "end_pos": 22 }, { "start_pos": 747, "end_pos": 749 }, { "start_pos": 777, "end_pos": 779 }, { "start_pos": 87, "end_pos": 89 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VNK1-1", "uniprot_ac": "Q9VNK1", "uniprot_id": "Q9VNK1_DROME", "mass": { "chemical_mass": 6368.0, "monoisotopic_mass": 6368.0 }, "refseq": { "ac": "NP_652319", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_652319" }, "gene_names": [ { "name": "Dmel\\CG11373", "type": "recommended", "evidence": [ { "id": "Q9VNK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VNK1" } ] }, { "name": "CG11373", "type": "synonym", "evidence": [ { "id": "NP_652319", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_652319" }, { "id": "Q9VNK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VNK1" } ] }, { "name": "Dmel\\CG11373", "type": "synonym", "evidence": [ { "id": "NP_652319", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_652319" } ] }, { "name": "Dmel_CG11373", "type": "synonym", "evidence": [ { "id": "Q9VNK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VNK1" } ] } ], "protein_names": [ { "name": "CG11373-PA", "type": "synonym", "evidence": [ { "id": "NP_652319", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_652319" } ] }, { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "Q9VNK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VNK1/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_652319", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_652319" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VNK1", "url": "https://www.uniprot.org/uniprotkb/Q9VNK1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG11373", "url": "https://www.uniprot.org/uniprotkb/Q9VNK1", "locus": { "chromosome": "3R", "start_pos": 5960294, "end_pos": 5960987, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0040679", "url": "https://www.ensemblgenomes.org/id/FBgn0040679" } ] } } ], "crossref": [ { "id": "FB:FBgn0040679", "url": "https://alliancegenome.org/gene/FB:FBgn0040679", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0040679", "url": "https://bgee.org/?page=gene&gene_id=FBgn0040679", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0040679", "url": "https://flybase.org/reports/FBgn0040679", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "50152", "url": "https://www.ncbi.nlm.nih.gov/gene/50152", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dme:Dmel_CG11373", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG11373", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PMPNTHD", "url": "https://omabrowser.org/oma/group/PMPNTHD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "NP_652319", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_652319", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VNK1", "url": "https://www.uniprot.org/uniprotkb/Q9VNK1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VNK1-1", "url": "https://www.uniprot.org/uniprotkb/Q9VNK1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPEKPSAKSAPRPLTSIKGTRPSTSSSNPTTSRSKPTGTGVVRPPLPNAHDRIWKIMKM", "length": 59, "header": "tr|Q9VNK1-1|Q9VNK1_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG11373 PE=4 SV=1 CANONICAL=Q9VNK1-1" }, "isoforms": [ { "isoform_ac": "Q9VNK1-1", "url": "https://www.uniprot.org/uniprotkb/Q9VNK1/entry#Q9VNK1-1", "sequence": { "sequence": "MPEKPSAKSAPRPLTSIKGTRPSTSSSNPTTSRSKPTGTGVVRPPLPNAHDRIWKIMKM", "length": 59, "header": "tr|Q9VNK1-1|Q9VNK1_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG11373 PE=4 SV=1 CANONICAL=Q9VNK1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VNK1", "url": "https://www.uniprot.org/uniprotkb/Q9VNK1" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VNK1", "url": "https://www.uniprot.org/uniprotkb/Q9VNK1" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VNK1", "url": "https://www.uniprot.org/uniprotkb/Q9VNK1" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VNK1", "url": "https://www.uniprot.org/uniprotkb/Q9VNK1" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VNK1", "url": "https://www.uniprot.org/uniprotkb/Q9VNK1" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VNK1", "url": "https://www.uniprot.org/uniprotkb/Q9VNK1" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VNK1", "url": "https://www.uniprot.org/uniprotkb/Q9VNK1" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VNK1", "url": "https://www.uniprot.org/uniprotkb/Q9VNK1" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VNK1", "url": "https://www.uniprot.org/uniprotkb/Q9VNK1" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VNM2", "url": "https://www.uniprot.org/uniprotkb/Q9VNM2" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VNM2", "url": "https://www.uniprot.org/uniprotkb/Q9VNM2" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VNM2", "url": "https://www.uniprot.org/uniprotkb/Q9VNM2" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VNM2", "url": "https://www.uniprot.org/uniprotkb/Q9VNM2" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VNM2", "url": "https://www.uniprot.org/uniprotkb/Q9VNM2" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VNM2", "url": "https://www.uniprot.org/uniprotkb/Q9VNM2" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VNM2", "url": "https://www.uniprot.org/uniprotkb/Q9VNM2" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi 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Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VNM4", "url": "https://www.uniprot.org/uniprotkb/Q9VNM4" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VNM4", "url": "https://www.uniprot.org/uniprotkb/Q9VNM4" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VNM4", "url": "https://www.uniprot.org/uniprotkb/Q9VNM4" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VNM4", "url": "https://www.uniprot.org/uniprotkb/Q9VNM4" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VNM4", "url": 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Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VNM4", "url": "https://www.uniprot.org/uniprotkb/Q9VNM4" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VNM4", "url": "https://www.uniprot.org/uniprotkb/Q9VNM4" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VNM4", "url": "https://www.uniprot.org/uniprotkb/Q9VNM4" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VNM4", "url": "https://www.uniprot.org/uniprotkb/Q9VNM4" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VNM7", "url": "https://www.uniprot.org/uniprotkb/Q9VNM7" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VNM7", "url": "https://www.uniprot.org/uniprotkb/Q9VNM7" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VNM7", "url": "https://www.uniprot.org/uniprotkb/Q9VNM7" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VNM7", "url": "https://www.uniprot.org/uniprotkb/Q9VNM7" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VNM7", "url": 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Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VNM7", "url": "https://www.uniprot.org/uniprotkb/Q9VNM7" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VNM7", "url": "https://www.uniprot.org/uniprotkb/Q9VNM7" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VNM7", "url": "https://www.uniprot.org/uniprotkb/Q9VNM7" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VNM7", "url": "https://www.uniprot.org/uniprotkb/Q9VNM7" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VNN2", "url": "https://www.uniprot.org/uniprotkb/Q9VNN2" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VNN2", "url": "https://www.uniprot.org/uniprotkb/Q9VNN2" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VNN2", "url": "https://www.uniprot.org/uniprotkb/Q9VNN2" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VNN2", "url": "https://www.uniprot.org/uniprotkb/Q9VNN2" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VNN2", "url": "https://www.uniprot.org/uniprotkb/Q9VNN2" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VNN2", "url": "https://www.uniprot.org/uniprotkb/Q9VNN2" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VNN2", "url": "https://www.uniprot.org/uniprotkb/Q9VNN2" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VNN2", "url": "https://www.uniprot.org/uniprotkb/Q9VNN2" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VNN2", "url": "https://www.uniprot.org/uniprotkb/Q9VNN2" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"categories": [ "Protein Classification", "Other" ] }, { "id": "NP_730768", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_730768", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VNP3", "url": "https://www.uniprot.org/uniprotkb/Q9VNP3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VNP3-1", "url": "https://www.uniprot.org/uniprotkb/Q9VNP3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPVSGCLPTATHSLQDMSAAAAAIALDMKPKLEPHPLAAATAMPSQKIKKLVRRNASDKLKLIQMVHDNPILWDSRLPNFKGAEEEKNRAWEHIGREFNAPGRRVARAFKSLRESYRRELAHVKLMGNGFKPKWSLYEAMDFLRDVIRERKGASHATDLSLTTYGHINNNNNNNNNSNSLAAGGKAMTLKLSNSFNESASVLNLSKCSSLNVSDDHYYCDYYVKPELDLSVGGGAGSSTSGSSSGGGPLPLPAHQAHNDSRVSSTRNEQRAQHHSYEDMDDSSIRSGDEDIAHASDVVEELDAIDADFPYPLILDSNSRGSPNVGVDDVVMSRKLRRNVDQDVLEEGNGHGDAVIDGDDYEEQMLQQHRHLRQQQGVASGGLDLPPPQTVREVLNSKFCGFISAKLNSMEDSDADNLMNRILLLLVQVQQCEGSTK", "length": 437, "header": "tr|Q9VNP3-1|Q9VNP3_DROME Isoform 1 of Mesoderm-expressed 2, isoform B OS=Drosophila melanogaster OX=7227 GN=Mes2 PE=1 SV=1 CANONICAL=Q9VNP3-1" }, "isoforms": [ { "isoform_ac": "Q9VNP3-1", "url": "https://www.uniprot.org/uniprotkb/Q9VNP3/entry#Q9VNP3-1", "sequence": { "sequence": "MAPVSGCLPTATHSLQDMSAAAAAIALDMKPKLEPHPLAAATAMPSQKIKKLVRRNASDKLKLIQMVHDNPILWDSRLPNFKGAEEEKNRAWEHIGREFNAPGRRVARAFKSLRESYRRELAHVKLMGNGFKPKWSLYEAMDFLRDVIRERKGASHATDLSLTTYGHINNNNNNNNNSNSLAAGGKAMTLKLSNSFNESASVLNLSKCSSLNVSDDHYYCDYYVKPELDLSVGGGAGSSTSGSSSGGGPLPLPAHQAHNDSRVSSTRNEQRAQHHSYEDMDDSSIRSGDEDIAHASDVVEELDAIDADFPYPLILDSNSRGSPNVGVDDVVMSRKLRRNVDQDVLEEGNGHGDAVIDGDDYEEQMLQQHRHLRQQQGVASGGLDLPPPQTVREVLNSKFCGFISAKLNSMEDSDADNLMNRILLLLVQVQQCEGSTK", "length": 437, "header": "tr|Q9VNP3-1|Q9VNP3_DROME Isoform 1 of Mesoderm-expressed 2, isoform B OS=Drosophila melanogaster OX=7227 GN=Mes2 PE=1 SV=1 CANONICAL=Q9VNP3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VNP3", "url": "https://www.uniprot.org/uniprotkb/Q9VNP3" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VNP3", "url": "https://www.uniprot.org/uniprotkb/Q9VNP3" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VNP3", "url": "https://www.uniprot.org/uniprotkb/Q9VNP3" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VNP3", "url": "https://www.uniprot.org/uniprotkb/Q9VNP3" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VNP3", "url": "https://www.uniprot.org/uniprotkb/Q9VNP3" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VNP3", "url": "https://www.uniprot.org/uniprotkb/Q9VNP3" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VNP3", "url": "https://www.uniprot.org/uniprotkb/Q9VNP3" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VNP3", "url": "https://www.uniprot.org/uniprotkb/Q9VNP3" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VNP3", "url": "https://www.uniprot.org/uniprotkb/Q9VNP3" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VNP3", "url": "https://www.uniprot.org/uniprotkb/Q9VNP3" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VNP3", "url": "https://www.uniprot.org/uniprotkb/Q9VNP3" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], 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"UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFSRHNIEKRRLIELVRLNPILWDCRLPHYKRSDKRKAIKWNELGRLFNVNGERVQRTFTSLREIFRRELNHEKMLGTTRFKSKWEYYDAMAFLKEVIRERKSRERIKHGSLDSAPVATGSSNNNNNCVSRNSSNNNSSSAALDEYQYFAPSDPNNPNNQPQLQPEPKSSLPVTIPSLSLTLSQLPVALQQQAQHLQALQLQPDVTLTSLQKQSLPTSLTNATPAPLAQTSPAQVLSSSRSCSSSPSIYIKDEPCSPAGGCPEEVMTGNGPEATRKKLATIRPQTKQQLKARLQLPTPKNSSSYATSPPHLIINANNELIDTDAGDLEEDLDDFDEDDDVTGRCSPIVGQSETMGADGRLSVGSIYIGDGGDCGRGMGRAHTQARHVPTSRELLYMKFGDFLAARLNTLHETVANELMNKMLLLIAEK", "length": 429, "header": "tr|Q9VNP4-1|Q9VNP4_DROME Isoform 1 of MADF domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG12768 PE=4 SV=1 CANONICAL=Q9VNP4-1" }, "isoforms": [ { "isoform_ac": "Q9VNP4-1", "url": "https://www.uniprot.org/uniprotkb/Q9VNP4/entry#Q9VNP4-1", "sequence": { "sequence": 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Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VNP4", "url": "https://www.uniprot.org/uniprotkb/Q9VNP4" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VNP4", "url": "https://www.uniprot.org/uniprotkb/Q9VNP4" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VNP4", "url": "https://www.uniprot.org/uniprotkb/Q9VNP4" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VNP4", "url": "https://www.uniprot.org/uniprotkb/Q9VNP4" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VNP4", "url": "https://www.uniprot.org/uniprotkb/Q9VNP4" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VNP4", "url": "https://www.uniprot.org/uniprotkb/Q9VNP4" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VNP4", "url": "https://www.uniprot.org/uniprotkb/Q9VNP4" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VNP4", "url": "https://www.uniprot.org/uniprotkb/Q9VNP4" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VNP4", "url": "https://www.uniprot.org/uniprotkb/Q9VNP4" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"MADDEQEDQKEYRWETGYEKTWEAIKDDEDGMLDGAIAEIIQKAKRQRQAQKSKQNRLGMMRHMFVVLDCSESMSVPDLKPTRLRCTVKLLELFIEEFFDQNPISQLGLIALKAKRAEKVTELTGTSRVHLKALESLANVSLTSEPSLQNGLDLALKSLKVVPSHASREIVIIMGSLTTCDPVDINLTIDELKKEGIRCSVISLSAEIHVARYLTQQTMGTFGAVLDDAHFRDQLMSQVDPPPAAKTQHNSLIRMGFPHTKNEVEGKDAPLSMCMCHIENLEEPSELTTTGHHCPQCNSKYCELPVECQSCGLTLVSAPHLARSYHHLFPVPNFEELPFEAMPASSSDLTSDVRECYGCAKALGQGVDKVADKVVFRCGFCKQFFCVDCDIFIHDTLHACVGCNTIPGVDGLVYQQSSKSDQVDAHPGPSKQRGQCGM", "length": 438, "header": "tr|Q9VNP8-1|Q9VNP8_DROME Isoform 1 of General transcription factor IIH subunit OS=Drosophila melanogaster OX=7227 GN=Ssl1 PE=1 SV=2 CANONICAL=Q9VNP8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum 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"https://www.uniprot.org/uniprotkb/Q9VNP8" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VNP8", "url": "https://www.uniprot.org/uniprotkb/Q9VNP8" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VNP8", "url": "https://www.uniprot.org/uniprotkb/Q9VNP8" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VNP8", "url": "https://www.uniprot.org/uniprotkb/Q9VNP8" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VNP8", "url": "https://www.uniprot.org/uniprotkb/Q9VNP8" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VNP8", "url": "https://www.uniprot.org/uniprotkb/Q9VNP8" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VNP8", "url": "https://www.uniprot.org/uniprotkb/Q9VNP8" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VNP8", "url": "https://www.uniprot.org/uniprotkb/Q9VNP8" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VNP8", "url": "https://www.uniprot.org/uniprotkb/Q9VNP8" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VNP8", "url": "https://www.uniprot.org/uniprotkb/Q9VNP8" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VNP8", "url": "https://www.uniprot.org/uniprotkb/Q9VNP8" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], 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"https://alliancegenome.org/gene/FB:FBgn0037202#orthology", "database": "AGR" }, { "id": "SGD:S000003995", "url": "https://alliancegenome.org/gene/SGD:S000003995#orthology", "database": "AGR" }, { "id": "Q9VNP8", "url": "https://omabrowser.org/oma/group/Q9VNP8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q2TBV5-1", "protein_name": "General transcription factor IIH subunit 2", "gene_name": "GTF2H2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDEEPERTKRWEGGYERTWEILKEDESGSLKATIEDILFKAKRKRVFEHHGQVRLGMMRHLYVVVDGSRTMEDQDLKPNRLTCTLKLLEYFVEEYFDQNPISQIGIIVTKSKRAEKLTELSGNPRKHITSLKKAVDMTCHGEPSLYNSLSMAMQTLKHMPGHTSREVLIIFSSLTTCDPSNIYDLIKSLKAAKIRVSIIGLSAEVRVCTALARETGGTYHVILDESHYKELLTHHVSPPPASSNSECSLIRMGFPQHTIASLSDQDAKPSFSMAHLDSNTEPGLTLGGYFCPQCRAKYCELPVECKICGLTLVSAPHLARSYHHLFPLDAFQEIPLEEHNGERFCYACQGELKDQHVYVCSVCQNVFCVDCDVFVHDSLHCCPGCIHKIPVPSGI", "length": 395 }, "evidence": [ { "id": "Q9VNP8", "url": "https://omabrowser.org/oma/group/Q9VNP8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q86KZ2-1", "protein_name": "General transcription factor IIH subunit 2", "gene_name": "gtf2h2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSKNIYNNNAQNKRTNRSLYDDEDGPAHVLQTNDEDGTNKYKWENRFEKTWLTIDEDEHGLRPSNQEERNTRNRRLKNKDRDGILSQDQRVRRGMQRHLCLILDLSKTLSNQDLKPSRYQVLLQNVELFIKEFFDQNPISQLSIIITKNSKAEKISELSGNRLRHIQAMKDAIAMEGEPSIQNSLEVALSSLCYVPKYGSREVLFIFSSLTTCDPSSLQKTIQSLKNESIRVSFIHMAAELYICKAIAEQTNGTSKVILNEEHFNESLMLKCQPPPTIGKTEAALVEMGFPQQITSTVPSPCICHEKMKYSGYICPRCGVKSCELPTDCQICNLSLVSSPHLARSYHHLFQIPLFNEVNWKELNKNVTCIGCLSSSEKSILSLFFSCPRCQEIFCLDCDLFIHESLHNCPGCENKLQNTNTNTNGKTNGNEITNGNGNGNGNENENGNGNGNGNGNGNGLH", "length": 461 }, "evidence": [ { "id": "Q9VNP8", "url": "https://omabrowser.org/oma/group/Q9VNP8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9JIB4-1", "protein_name": "General transcription factor IIH subunit 2", "gene_name": "Gtf2h2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDEEPERTKRWEGGYERTWEILKEDETGSLKATIEDILFKAKRKRVFEHHGQVRLGMMRHLYVVVDGSRTMEDQDLKPNRLTCTLKLLEYFVEEYFDQNPISQIGIIVTKSKRAEKLTELSGNPRKHITSLKKAVDMTCHGEPSLYNSLSMAMQTLKHMPGHTSREVLIIFSSLTTCDPSNIYDLIKTLKTAKIRVSVIGLSAEVRVCTVLARETGGTYHVILDETHYKELLAHHVSPPPASSSSECSLIRMGFPQHTIASLSDQDAKPSFSMAHLDNNSTEPGLTLGGYFCPQCRAKYCELPVECKICGLTLVSAPHLARSYHHLFPLDAFQEISLEEYKGERFCYGCQGELKDQHVYVCTVCQNVFCVDCDVFVHDSLHCCPGCIHKIPTPSGI", "length": 396 }, "evidence": [ { "id": "RGD:1310499", "url": "https://alliancegenome.org/gene/RGD:1310499#orthology", "database": "AGR" }, { "id": "MGI:1345669", "url": "https://alliancegenome.org/gene/MGI:1345669#orthology", "database": "AGR" }, { "id": "HGNC:4656", "url": "https://alliancegenome.org/gene/HGNC:4656#orthology", "database": "AGR" }, { "id": "HGNC:31394", "url": 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"MSNQRKRSNDEREEEDDEDAEGIGEWERAYVDDRSWEELQEDESGLLRPIDNSAIYHAQYRRRLRMLSAAAAGTRIQKGLIRYLYIVIDFSRAAAEMDFRPSRMAIMAKHVEAFIREFFDQNPLSQIGLVSIKNGVAHTLTDLGGSPETHIKALMGKLEALGDSSLQNALELVHEHLNQVPSYGHREVLILYSALCTCDPGDIMETIQKCKKSKLRCSVIGLSAEMFICKHLCQETGGLYSVAVDEVHLKDLLLEHAPPPPAIAEFAIANLIKMGFPQRAAEGSMAICSCHKEVKIGAGYMCPRCKARVCDLPTECTICGLTLVSSPHLARSYHHLFPIAPFDEVPALSSLNDNRRKLGKSCFGCQQSLIGAGNKPVPCVTCRKCKHYFCLDCDIYIHESLHNCPGCESIHRPKSVSLMEE", "length": 421 }, "evidence": [ { "id": "Q9VNP8", "url": "https://omabrowser.org/oma/group/Q9VNP8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VNP8", "url": "https://www.uniprot.org/uniprotkb/Q9VNP8" } ], "pmid": "" }, { "name": "transcription factor TFIIH holo complex", "id": 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"database": "UniProtKB", "id": "Q9VNP8", "url": "https://www.uniprot.org/uniprotkb/Q9VNP8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9VNP8", "url": "https://www.uniprot.org/uniprotkb/Q9VNP8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VNP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VNP8" }, { "id": "PS50234", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50234" } ], 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"name": "NADH dehydrogenase (ubiquinone) B14.5 A subunit-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649399" }, "gene_names": [ { "name": "ND-B14.5AL", "type": "recommended", "evidence": [ { "id": "Q9VNT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VNT3" } ] }, { "name": "BcDNA:AT13913", "type": "synonym", "evidence": [ { "id": "NP_649399", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649399" }, { "id": "Q9VNT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VNT3" } ] }, { "name": "CG6914", "type": "synonym", "evidence": [ { "id": "NP_649399", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649399" }, { "id": "Q9VNT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VNT3" } ] }, { "name": "Dmel\\CG6914", "type": "synonym", "evidence": [ { "id": "NP_649399", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649399" }, { "id": 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subcomplex subunit 7", "type": "recommended", "evidence": [ { "id": "Q9VNT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VNT3/entry#names_and_taxonomy" } ] }, { "name": "CG6914-PA", "type": "synonym", "evidence": [ { "id": "NP_649399", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649399" } ] }, { "name": "Complex I-B14.5a", "type": "synonym", "evidence": [ { "id": "Q9VNT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VNT3/entry#names_and_taxonomy" } ] }, { "name": "NADH dehydrogenase (ubiquinone) B14.5 A subunit-like", "type": "synonym", "evidence": [ { "id": "NP_649399", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649399" } ] }, { "name": "NADH-ubiquinone oxidoreductase subunit B14.5a", "type": "synonym", "evidence": [ { "id": "NP_649399", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649399" }, { "id": "Q9VNT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VNT3/entry#names_and_taxonomy" } ] }, { "name": "NADH:ubiquinone oxidoreductase B14.5A subunit", "type": "synonym", "evidence": [ { "id": "NP_649399", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649399" } ] }, { "name": "ND-B14.5AL-PA", "type": "synonym", "evidence": [ { "id": "NP_649399", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649399" } ] } ], "function": [ { "annotation": "Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. 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"MPPKPKHRDVAGFLSRVRNFLLGRTHKTAHRFADMVSPRTQPPPNIPSGPTQSLFANYYYTRDPRRLVKPFVDVVQEHKKMLTAKVKEEEAAKKAQAKSGDAPKDGSPIPPVGPKTTDTNECDEGNSGAKKLPTPGKVHSWEGPH", "length": 145, "header": "tr|Q9VNT3-1|Q9VNT3_DROME Isoform 1 of NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 OS=Drosophila melanogaster OX=7227 GN=ND-B14.5AL PE=3 SV=1 CANONICAL=Q9VNT3-1" }, "isoforms": [ { "isoform_ac": "Q9VNT3-1", "url": "https://www.uniprot.org/uniprotkb/Q9VNT3/entry#Q9VNT3-1", "sequence": { "sequence": "MPPKPKHRDVAGFLSRVRNFLLGRTHKTAHRFADMVSPRTQPPPNIPSGPTQSLFANYYYTRDPRRLVKPFVDVVQEHKKMLTAKVKEEEAAKKAQAKSGDAPKDGSPIPPVGPKTTDTNECDEGNSGAKKLPTPGKVHSWEGPH", "length": 145, "header": "tr|Q9VNT3-1|Q9VNT3_DROME Isoform 1 of NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 OS=Drosophila melanogaster OX=7227 GN=ND-B14.5AL PE=3 SV=1 CANONICAL=Q9VNT3-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 51, "start_aa": "Thr", "end_pos": 51, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr51", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VNT3", "url": "https://www.uniprot.org/uniprotkb/Q9VNT3" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VNT3", "url": "https://www.uniprot.org/uniprotkb/Q9VNT3" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VNT3", "url": "https://www.uniprot.org/uniprotkb/Q9VNT3" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VNT3", "url": "https://www.uniprot.org/uniprotkb/Q9VNT3" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VNT3", "url": "https://www.uniprot.org/uniprotkb/Q9VNT3" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VNT3", "url": "https://www.uniprot.org/uniprotkb/Q9VNT3" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VNT3", "url": "https://www.uniprot.org/uniprotkb/Q9VNT3" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VNT3", "url": "https://www.uniprot.org/uniprotkb/Q9VNT3" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VNT3", "url": "https://www.uniprot.org/uniprotkb/Q9VNT3" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VNT3", "url": "https://www.uniprot.org/uniprotkb/Q9VNT3" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VNT3", "url": "https://www.uniprot.org/uniprotkb/Q9VNT3" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], 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"tr|Q9VNU2-1|Q9VNU2_DROME Isoform 1 of Lazaro OS=Drosophila melanogaster OX=7227 GN=laza PE=3 SV=1 CANONICAL=Q9VNU2-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 325, "start_aa": "Thr", "end_pos": 325, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr325", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VNU2", "url": "https://www.uniprot.org/uniprotkb/Q9VNU2" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VNU2", "url": "https://www.uniprot.org/uniprotkb/Q9VNU2" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VNU2", "url": "https://www.uniprot.org/uniprotkb/Q9VNU2" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VNU2", "url": "https://www.uniprot.org/uniprotkb/Q9VNU2" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VNU2", "url": "https://www.uniprot.org/uniprotkb/Q9VNU2" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VNU2", "url": "https://www.uniprot.org/uniprotkb/Q9VNU2" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VNU2", "url": "https://www.uniprot.org/uniprotkb/Q9VNU2" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VNU2", "url": "https://www.uniprot.org/uniprotkb/Q9VNU2" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VNU2", "url": "https://www.uniprot.org/uniprotkb/Q9VNU2" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VNU2", "url": "https://www.uniprot.org/uniprotkb/Q9VNU2" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VNU2", "url": "https://www.uniprot.org/uniprotkb/Q9VNU2" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG11440", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG11440", "resource": "KEGG Pathway" }, { "id": "R-DME-419408", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-419408", "resource": "Reactome", "description": "Lysosphingolipid and LPA receptors" }, { "id": "R-DME-9845614", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9845614", "resource": "Reactome", "description": "Sphingolipid catabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1PDR3-1", "protein_name": "3.1.3.4", "gene_name": "plpp2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDMGKKKLFVLVDVMCVVVASLPFVAMTIASHPYERGIFCQDESIGYPVKTDTITNVTLAAVTITCTILIICSGEAYLVYSKKIHSNSSFNQYVSAIYKVLGAFLFGGAVSQSLTDLAKYTIGRPRPNFLAVCAPKVCKGFVNLNNCTGNPADVTEARLSFYSGHSSFAMYCMLFLAFYVQARLNAKWARLLRPTIQFFLVAFAVYVGYTRVSDYKHHWSDVMVGLLQGALIAILTVRFVSNFFKVSPSPECSNQENAVNEERKPSNSYRYSGPV", "length": 276 }, "evidence": [ { "id": "MGI:1354945", "url": "https://alliancegenome.org/gene/MGI:1354945#orthology", "database": "AGR" }, { "id": "HGNC:9230", "url": "https://alliancegenome.org/gene/HGNC:9230#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-7425", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-7425#orthology", "database": "AGR" }, { "id": "FB:FBgn0037163", "url": "https://alliancegenome.org/gene/FB:FBgn0037163#orthology", "database": "AGR" }, { "id": "RGD:628893", "url": "https://alliancegenome.org/gene/RGD:628893#orthology", "database": "AGR" }, { "id": "SGD:S000002911", "url": "https://alliancegenome.org/gene/SGD:S000002911#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58GLC3-1", "protein_name": "Phospholipid phosphatase 1", "gene_name": "plpp1a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MQLYWGKYSTLLTFVLFLSLLFLLVGLPFAILTIQHKSFKRGFFCNDDSIKYPYKEDTISYQLLGGVMIPVTLLTMIIGECLSVYLNRIKSNSFCNGYVACVYKAIGTFVFGAAISQSLTDIAKYSIGRLRPHFLDVCKPDWSKINCTAGAYIEDFVCTGKESVVNEGRLSFYSGHSSFSMYCMLFLALYLQARMQAEWARLLRPTLQFFLIAASVYTGLSRVSDYKHHWSDVLTGLIQGAIVALLVVFFVSDFFKKKVEPQKETEIPHTTLQETPTNGNHYDNPN", "length": 286 }, "evidence": [ { "id": "MGI:108412", "url": "https://alliancegenome.org/gene/MGI:108412#orthology", "database": "AGR" }, { "id": "HGNC:9228", "url": "https://alliancegenome.org/gene/HGNC:9228#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ACD6B5N7-1", "protein_name": "Phospholipid phosphatase 2", "gene_name": "plpp2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSELKKNRMFIVLMDLLCVAVVAMPFIIMTIMYRPYHRGVYCNDETIQYPYRPDTISHKMMAAVTISCSVIIIISGEAYLVYTKRLYSNSDFNQYAAALYKVVGTFLFGACVSQSLTDMAKYTIGRLRPNFMSVCAPAVCEGYMLEINCTGNARNVTESRLSFYSGHSSFGMYCMLFLALYVQARLASKWARLLRPTIQFFLVAFAIYVGYTRVSDYKHHWSDVVVGLLQGALVAVLTVRYISDFFKERPPRCPDVENAENADVERKPSLQIADTDRNNYYPISRPV", "length": 287 }, "evidence": [ { "id": "MGI:1354945", "url": "https://alliancegenome.org/gene/MGI:1354945#orthology", "database": "AGR" }, { "id": "HGNC:9230", "url": "https://alliancegenome.org/gene/HGNC:9230#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1Q6K0-1", "protein_name": "Phospholipid phosphatase 3", "gene_name": "plpp3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MQNYMYEKAMAPETRNGGTSTLNNNGVNNSKRKLLIALDIFCLVLAVLPFLIIETSTIKPYHRGFYCSDQSIQYPYKNGDTISDAVLCAAGILIVIFSIVIGECYRIHYLSQGSKSFVGNPYVSALYRQVGVFIFGCAVSQSFTDIAKVSVGRMRPHFLDVCRPNYSTIDCSLGYITEYTCTGDPSKVQEARKSFFSGHASFSMYTMLYLAFYLQSRFTWRGARLLRPLLQFTLLMMAFYTGLSRVSDHKHHPTDVLAGFVQGALVAYCIVFYVSDLFKPKAKTATPPPSPIKKELLPSSDIIERNNHHNMV", "length": 312 }, "evidence": [ { "id": "MGI:1915166", "url": "https://alliancegenome.org/gene/MGI:1915166#orthology", "database": "AGR" }, { "id": "HGNC:9229", "url": "https://alliancegenome.org/gene/HGNC:9229#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O08564-1", "protein_name": "Phospholipid phosphatase 1", "gene_name": "Plpp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFDKPRLPYVVLDVICVLLAGLPFIILTSRHTPFQRGVFCTDESIKYPYREDTIPYALLGGIVIPFCIIVMITGETLSVYFNVLHSNSFVSNHYIATIYKAVGAFLFGASASQSLTDIAKYSIGRLRPHFLAVCNPDWSKINCSDGYIENFVCQGNEQKVREGRLSFYSGHSSFSMYCMLFVALYLQARMKGDWARLLRPMLQFGLVALSIYVGLSRVSDYKHHWSDVLIGLIQGAVVAILVVLYVTDFFKTTESNKERKEDSHTTLHETTNRQSYARNHEP", "length": 282 }, "evidence": [ { "id": "MGI:108412", "url": "https://alliancegenome.org/gene/MGI:108412#orthology", "database": "AGR" }, { "id": "HGNC:9228", "url": "https://alliancegenome.org/gene/HGNC:9228#orthology", "database": "AGR" }, { "id": "FB:FBgn0037163", "url": "https://alliancegenome.org/gene/FB:FBgn0037163#orthology", "database": "AGR" }, { "id": "RGD:621832", "url": "https://alliancegenome.org/gene/RGD:621832#orthology", "database": "AGR" }, { "id": "SGD:S000002911", "url": "https://alliancegenome.org/gene/SGD:S000002911#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O14494-1", "protein_name": "Phospholipid phosphatase 1", "gene_name": "PLPP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFDKTRLPYVALDVLCVLLAGLPFAILTSRHTPFQRGVFCNDESIKYPYKEDTIPYALLGGIIIPFSIIVIILGETLSVYCNLLHSNSFIRNNYIATIYKAIGTFLFGAAASQSLTDIAKYSIGRLRPHFLDVCDPDWSKINCSDGYIEYYICRGNAERVKEGRLSFYSGHSSFSMYCMLFVALYLQARMKGDWARLLRPTLQFGLVAVSIYVGLSRVSDYKHHWSDVLTGLIQGALVAILVAVYVSDFFKERTSFKERKEEDSHTTLHETPTTGNHYPSNHQP", "length": 284 }, "evidence": [ { "id": "MGI:108412", "url": "https://alliancegenome.org/gene/MGI:108412#orthology", "database": "AGR" }, { "id": "HGNC:9228", "url": "https://alliancegenome.org/gene/HGNC:9228#orthology", "database": "AGR" }, { "id": "FB:FBgn0037163", "url": "https://alliancegenome.org/gene/FB:FBgn0037163#orthology", "database": "AGR" }, { "id": "RGD:621832", "url": "https://alliancegenome.org/gene/RGD:621832#orthology", "database": "AGR" }, { "id": "SGD:S000002911", "url": "https://alliancegenome.org/gene/SGD:S000002911#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O14495-1", "protein_name": "Phospholipid phosphatase 3", "gene_name": "PLPP3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQNYKYDKAIVPESKNGGSPALNNNPRRSGSKRVLLICLDLFCLFMAGLPFLIIETSTIKPYHRGFYCNDESIKYPLKTGETINDAVLCAVGIVIAILAIITGEFYRIYYLKKSRSTIQNPYVAALYKQVGCFLFGCAISQSFTDIAKVSIGRLRPHFLSVCNPDFSQINCSEGYIQNYRCRGDDSKVQEARKSFFSGHASFSMYTMLYLVLYLQARFTWRGARLLRPLLQFTLIMMAFYTGLSRVSDHKHHPSDVLAGFAQGALVACCIVFFVSDLFKTKTTLSLPAPAIRKEILSPVDIIDRNNHHNMM", "length": 311 }, "evidence": [ { "id": "MGI:1915166", "url": "https://alliancegenome.org/gene/MGI:1915166#orthology", "database": "AGR" }, { "id": "HGNC:9229", "url": "https://alliancegenome.org/gene/HGNC:9229#orthology", "database": "AGR" }, { "id": "FB:FBgn0037163", "url": "https://alliancegenome.org/gene/FB:FBgn0037163#orthology", "database": "AGR" }, { "id": "RGD:620454", "url": "https://alliancegenome.org/gene/RGD:620454#orthology", "database": "AGR" }, { "id": "SGD:S000002911", "url": "https://alliancegenome.org/gene/SGD:S000002911#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O43688-1", "protein_name": "Phospholipid phosphatase 2", "gene_name": "PLPP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQRRWVFVLLDVLCLLVASLPFAILTLVNAPYKRGFYCGDDSIRYPYRPDTITHGLMAGVTITATVILVSAGEAYLVYTDRLYSRSDFNNYVAAVYKVLGTFLFGAAVSQSLTDLAKYMIGRLRPNFLAVCDPDWSRVNCSVYVQLEKVCRGNPADVTEARLSFYSGHSSFGMYCMVFLALYVQARLCWKWARLLRPTVQFFLVAFALYVGYTRVSDYKHHWSDVLVGLLQGALVAALTVCYISDFFKARPPQHCLKEEELERKPSLSLTLTLGEADHNHYGYPHSSS", "length": 288 }, "evidence": [ { "id": "MGI:1354945", "url": "https://alliancegenome.org/gene/MGI:1354945#orthology", "database": "AGR" }, { "id": "HGNC:9230", "url": "https://alliancegenome.org/gene/HGNC:9230#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-7425", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-7425#orthology", "database": "AGR" }, { "id": "FB:FBgn0037163", "url": "https://alliancegenome.org/gene/FB:FBgn0037163#orthology", "database": "AGR" }, { "id": "RGD:628893", "url": "https://alliancegenome.org/gene/RGD:628893#orthology", "database": "AGR" }, { "id": "SGD:S000002911", "url": "https://alliancegenome.org/gene/SGD:S000002911#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P97544-1", "protein_name": "Phospholipid phosphatase 3", "gene_name": "Plpp3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQSYKYDKAIVPESKNGGSPALNNNPRKGGSKRVLLICLDLFCLFMAALPFLIIETSTIKPYRRGFYCNDESIKYPLKVSETINDAVLCAVGIVIAILRIITGEFYRIYYLKEKSRSTIQNPYVAALYKQVGCFLFGCAISQSFTDIAKVSIGRLRPHFLSVCDPDFSQINCSEGYIQNYRCRGEDSKVQEARKSFFSGHASFSMFTMLYLVLYLQARFTWRGARLLRPLLQFTLLMMAFYTGLSRVSDYKHHPSDVLAGFAQGALVACCIVFFVSDLFKTKTTLSLPAPAIRREILSPVDIMDRSNHHNMV", "length": 312 }, "evidence": [ { "id": "MGI:1915166", "url": "https://alliancegenome.org/gene/MGI:1915166#orthology", "database": "AGR" }, { "id": "HGNC:9229", "url": "https://alliancegenome.org/gene/HGNC:9229#orthology", "database": "AGR" }, { "id": "FB:FBgn0037163", "url": "https://alliancegenome.org/gene/FB:FBgn0037163#orthology", "database": "AGR" }, { "id": "RGD:620454", "url": "https://alliancegenome.org/gene/RGD:620454#orthology", "database": "AGR" }, { "id": "SGD:S000002911", "url": "https://alliancegenome.org/gene/SGD:S000002911#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q04396-1", "protein_name": "Lipid phosphate phosphatase 1", "gene_name": "LPP1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MISVMADEKHKEYFKLYYFQYMIIGLCTILFLYSEISLVPRGQNIEFSLDDPSISKRYVPNELVGPLECLILSVGLSNMVVFWTCMFDKDLLKKNRVKRLRERPDGISNDFHFMHTSILCLMLIISINAALTGALKLIIGNLRPDFVDRCIPDLQKMSDSDSLVFGLDICKQTNKWILYEGLKSTPSGHSSFIVSTMGFTYLWQRVFTTRNTRSCIWCPLLALVVMVSRVIDHRHHWYDVVSGAVLAFLVIYCCWKWTFTNLAKRDILPSPVSV", "length": 274 }, "evidence": [ { "id": "MGI:1354945", "url": "https://alliancegenome.org/gene/MGI:1354945#orthology", "database": "AGR" }, { "id": "MGI:108412", "url": "https://alliancegenome.org/gene/MGI:108412#orthology", "database": "AGR" }, { "id": "MGI:1915166", "url": "https://alliancegenome.org/gene/MGI:1915166#orthology", "database": "AGR" }, { "id": "HGNC:9229", "url": "https://alliancegenome.org/gene/HGNC:9229#orthology", "database": "AGR" }, { "id": "HGNC:9230", "url": "https://alliancegenome.org/gene/HGNC:9230#orthology", "database": "AGR" }, { "id": "HGNC:9228", "url": "https://alliancegenome.org/gene/HGNC:9228#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-7425", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-7425#orthology", "database": "AGR" }, { "id": "FB:FBgn0037163", "url": "https://alliancegenome.org/gene/FB:FBgn0037163#orthology", "database": "AGR" }, { "id": "RGD:621832", "url": "https://alliancegenome.org/gene/RGD:621832#orthology", "database": "AGR" }, { "id": "RGD:620454", "url": "https://alliancegenome.org/gene/RGD:620454#orthology", "database": "AGR" }, { "id": "RGD:628893", "url": "https://alliancegenome.org/gene/RGD:628893#orthology", "database": "AGR" }, { "id": "SGD:S000002911", "url": "https://alliancegenome.org/gene/SGD:S000002911#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q61469-1", "protein_name": "Phospholipid phosphatase 1", "gene_name": "Plpp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFDKTRLPYVALDVICVLLAGLPFAILTSRHTPFQRGIFCNDDSIKYPYKEDTIPYALLGGIVIPFCIIVMSIGESLSVYFNVLHSNSFVGNPYIATIYKAVGAFLFGVSASQSLTDIAKYTIGSLRPHFLAICNPDWSKINCSDGYIEDYICQGNEEKVKEGRLSFYSGHSSFSMYCMLFVALYLQARMKGDWARLLRPMLQFGLIAFSIYVGLSRVSDYKHHWSDVTVGLIQGAAMAILVALYVSDFFKDTHSYKERKEEDPHTTLHETASSRNYSTNHEP", "length": 283 }, "evidence": [ { "id": "MGI:108412", "url": "https://alliancegenome.org/gene/MGI:108412#orthology", "database": "AGR" }, { "id": "HGNC:9228", "url": "https://alliancegenome.org/gene/HGNC:9228#orthology", "database": "AGR" }, { "id": "FB:FBgn0037163", "url": "https://alliancegenome.org/gene/FB:FBgn0037163#orthology", "database": "AGR" }, { "id": "RGD:621832", "url": "https://alliancegenome.org/gene/RGD:621832#orthology", "database": "AGR" }, { "id": "SGD:S000002911", "url": "https://alliancegenome.org/gene/SGD:S000002911#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8K593-1", "protein_name": "Phospholipid phosphatase 2", "gene_name": "Plpp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MERRWVFVLLDVLCVLVASLPFIILTLVNAPYKRGFYCGDDSIRYPYRPDTITHGLMAGVIITATVVLVSSGEAYLVYTDRLYSRSDFNNYVAAIYKVLGTFLFGAAVSQSLTDLAKYMIGRLRPSFLAVCDPDWSRVNCSGYVQVEVCRGSPANVTEARLSFYSGHSSFGMYCMLFLALYVQARLCWKWARLLRPTVQFFLVAFAIYVGYTRVSDNKHHWSDVLVGLLQGALVACLTVCYVSDFFKSRPPQSCQENEESERKPSLSLTLTLGDRP", "length": 276 }, "evidence": [ { "id": "MGI:1354945", "url": "https://alliancegenome.org/gene/MGI:1354945#orthology", "database": "AGR" }, { "id": "HGNC:9230", "url": "https://alliancegenome.org/gene/HGNC:9230#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-7425", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-7425#orthology", "database": "AGR" }, { "id": "FB:FBgn0037163", "url": "https://alliancegenome.org/gene/FB:FBgn0037163#orthology", "database": "AGR" }, { "id": "RGD:628893", "url": "https://alliancegenome.org/gene/RGD:628893#orthology", "database": "AGR" }, { "id": "SGD:S000002911", "url": "https://alliancegenome.org/gene/SGD:S000002911#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q99JY8-1", "protein_name": "Phospholipid phosphatase 3", "gene_name": "Plpp3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQSYKYDKAIVPESKNGGSPALNNNPRKGGSKRVLLICLDLFCLFMAALPFLIIETSTIKPYRRGFYCNDESIKYPLKVSETINDAVLCAVGIVIAILAIITGEFYRIYYLKEKSRSTTQNPYVAALYKQVGCFLFGCAISQSFTDIAKVSIGRLRPHFLSVCDPDFSQINCSEGYIQNYRCRGEDSKVQEARKSFFSGHASFSMFTMLYLVLYLQARFTWRGARLLRPLLQFTLLMMAFYTGLSRVSDYKHHPSDVLAGFAQGALVACCIVFFVSDLFKTKTSLSLPAPAIRREILSPVDIIDRNNHHNMV", "length": 312 }, "evidence": [ { "id": "MGI:1915166", "url": "https://alliancegenome.org/gene/MGI:1915166#orthology", "database": "AGR" }, { "id": "HGNC:9229", "url": "https://alliancegenome.org/gene/HGNC:9229#orthology", "database": "AGR" }, { "id": "FB:FBgn0037163", "url": "https://alliancegenome.org/gene/FB:FBgn0037163#orthology", "database": "AGR" }, { "id": "RGD:620454", "url": "https://alliancegenome.org/gene/RGD:620454#orthology", "database": "AGR" }, { "id": "SGD:S000002911", "url": "https://alliancegenome.org/gene/SGD:S000002911#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9DAX2-1", "protein_name": "Phospholipid phosphatase 2", "gene_name": "Plpp2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERRWVFVLLDVLCVLVASLPFIILTLVNAPYKRGFYCGDDSIRYPYRPDTITHGLMAGVIITATVILVSLGEAYLVYTDRLYSRSNFNNYVAAIYKVLGTFLFGAAVSQSLTDLAKYMIGRLRPSFLAVCDPDWSQVNCSGYVQLEVCRGSPANVTEARLSFYSGHSSFGMYCMLFLALYVQARLCWKWARLLRPTVQFFLVAFAIYVGYTRVSDHKHHWSDVLVGLLQGALVACLTVRYVSDFFKSRPPQPCQEDEVPERKPSLSLTLTLGDRP", "length": 276 }, "evidence": [ { "id": "MGI:1354945", "url": "https://alliancegenome.org/gene/MGI:1354945#orthology", "database": "AGR" }, { "id": "HGNC:9230", "url": "https://alliancegenome.org/gene/HGNC:9230#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-7425", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-7425#orthology", "database": "AGR" }, { "id": "FB:FBgn0037163", "url": "https://alliancegenome.org/gene/FB:FBgn0037163#orthology", "database": "AGR" }, { "id": "RGD:628893", "url": "https://alliancegenome.org/gene/RGD:628893#orthology", "database": "AGR" }, { "id": "SGD:S000002911", "url": "https://alliancegenome.org/gene/SGD:S000002911#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9V576-1", "protein_name": "Putative phosphatidate phosphatase", "gene_name": "wun", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPAVKIIMSTETSASETTPLRRSENETPDHKELAQSNSNSRQTTVNSNNNNYSNSVQVRLQEQDRDSDSEQQQHTATITMDTNKRILCRVGLDVLILLCAGFPILLFFLLGEPYKRGFFCDDESLKHPFHDSTVRNWMLYFIGAVIPVGVIFIVEVIISQNKAKQDNGNATSRRYVFMNYELPDWMIECYKKIGIYAFGAVLSQLTTDIAKYSIGRLRPHFIAVCQPQMADGSTCDDAINAGKYIQEFTCKGVGSSARMLKEMRLSFPSGHSSFTFFAMVYLALYLQARMTWRGSKLLRHLLQFLFIMVAWYTALSRVSDYKHHWSDVLAGSLIGSISALVVANYVSDLFQKPNTKPYLARTVQDMNASPAQAITITTN", "length": 379 }, "evidence": [ { "id": "MGI:1354945", "url": "https://alliancegenome.org/gene/MGI:1354945#orthology", "database": "AGR" }, { "id": "MGI:108412", "url": "https://alliancegenome.org/gene/MGI:108412#orthology", "database": "AGR" }, { "id": "MGI:1915166", "url": "https://alliancegenome.org/gene/MGI:1915166#orthology", "database": "AGR" }, { "id": "HGNC:9229", "url": "https://alliancegenome.org/gene/HGNC:9229#orthology", "database": "AGR" }, { "id": "HGNC:9230", "url": "https://alliancegenome.org/gene/HGNC:9230#orthology", "database": "AGR" }, { "id": "HGNC:9228", "url": "https://alliancegenome.org/gene/HGNC:9228#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-7425", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-7425#orthology", "database": "AGR" }, { "id": "RGD:621832", "url": "https://alliancegenome.org/gene/RGD:621832#orthology", "database": "AGR" }, { "id": "RGD:620454", "url": "https://alliancegenome.org/gene/RGD:620454#orthology", "database": "AGR" }, { "id": "RGD:628893", "url": "https://alliancegenome.org/gene/RGD:628893#orthology", "database": "AGR" }, { "id": "SGD:S000002911", "url": "https://alliancegenome.org/gene/SGD:S000002911#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VNT8-1", "protein_name": "Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein", "gene_name": "WUN-like", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSFNLSLRPPIRLLVDLVLLGLLIVLVENFRRLWGPPTKRGFFCDDESLMYPYHENTVSPTLLHWLGLYLPLISLVVLESFLSHRKDMAPWPTLWPVYNTVRWFLYGYVSNDLLKGIGKQALGRLRPHFFAVCSPHFPDGSSCLDESHRGALKYHTDYECRPNLSQATEEMIRDVNVSFPSGHSAMAFYGLVFVALHLRRRRWPLRGSLLSPVLQLACVALAWFVAISRVIDYKHHWSDVAAGSLLGAGSALAVTRAAASEELQWRCQDSLASAKQEAAVVDVADVKGGQQMPHDLSLVTCHISN", "length": 305 }, "evidence": [ { "id": "MGI:1354945", "url": "https://alliancegenome.org/gene/MGI:1354945#orthology", "database": "AGR" }, { "id": "MGI:108412", "url": "https://alliancegenome.org/gene/MGI:108412#orthology", "database": "AGR" }, { "id": "MGI:1915166", "url": "https://alliancegenome.org/gene/MGI:1915166#orthology", "database": "AGR" }, { "id": "HGNC:9229", "url": "https://alliancegenome.org/gene/HGNC:9229#orthology", "database": "AGR" }, { "id": "HGNC:9230", "url": "https://alliancegenome.org/gene/HGNC:9230#orthology", "database": "AGR" }, { "id": "HGNC:9228", "url": "https://alliancegenome.org/gene/HGNC:9228#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-7425", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-7425#orthology", "database": "AGR" }, { "id": "RGD:621832", "url": "https://alliancegenome.org/gene/RGD:621832#orthology", "database": "AGR" }, { "id": "RGD:620454", "url": "https://alliancegenome.org/gene/RGD:620454#orthology", "database": "AGR" }, { "id": "RGD:628893", "url": "https://alliancegenome.org/gene/RGD:628893#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VNT9-1", "protein_name": "Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein", "gene_name": "WUN-like", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRDAPEDQSVTVSMPASASGSAAGSTGPSSDRRMTQRLLVELLVVVVLVIPICVYEFAVDPVRRGFFCDDESISYPFQDNTITPVMLGLIVGLLPALVMVVVEYVSHLRAGDISATVDLLGWRVSTWYVELGRQSTYFCFGLLLTFDATEVGKYTIGRLRPHFLAVCQPQIADGSMCSDPVNLHRYMENYDCAGEGFTVEDVRQARLSFPSGHSSLAFYAMIYVALYLQRKITWRGSKLSRHFVQFAVVMVAWYTALSRVMDHWHHWSDVLSGSLLGVAGALITAHYIARMFDDGASNILSGGLRRENTAATLQEEVCPTTPPPYSVNNSFSEDQYCSKV", "length": 340 }, "evidence": [ { "id": "MGI:1354945", "url": "https://alliancegenome.org/gene/MGI:1354945#orthology", "database": "AGR" }, { "id": "MGI:108412", "url": "https://alliancegenome.org/gene/MGI:108412#orthology", "database": "AGR" }, { "id": "MGI:1915166", "url": "https://alliancegenome.org/gene/MGI:1915166#orthology", "database": "AGR" }, { "id": "HGNC:9229", "url": "https://alliancegenome.org/gene/HGNC:9229#orthology", "database": "AGR" }, { "id": "HGNC:9230", "url": "https://alliancegenome.org/gene/HGNC:9230#orthology", "database": "AGR" }, { "id": "HGNC:9228", "url": "https://alliancegenome.org/gene/HGNC:9228#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-7425", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-7425#orthology", "database": "AGR" }, { "id": "RGD:621832", "url": "https://alliancegenome.org/gene/RGD:621832#orthology", "database": "AGR" }, { "id": "RGD:620454", "url": "https://alliancegenome.org/gene/RGD:620454#orthology", "database": "AGR" }, { "id": "RGD:628893", "url": "https://alliancegenome.org/gene/RGD:628893#orthology", "database": "AGR" }, { "id": "SGD:S000002911", "url": "https://alliancegenome.org/gene/SGD:S000002911#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VNU0-1", "protein_name": "Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein", "gene_name": "LPP-like", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MCGNPNTRLLSRLVIDFLILLGIYGAALVVLPQQLSTAQRGFHCSDTSLKYPYRQPWLTKVHLTIAVVALPAAFVLVVEMLRAAVVPSSTELTQRFVFVGVRIPRFISECYKAIGVYLFGLGLTLAAIRLTKHSTGRLRPYFFDICQPTWGTEGGESCSDVTAQNSTLYLEDFSCTEFAASQDLLALVRHSFPSGFVSTTCYAMGFLIFYSQARLFAPWLRLVRASLQLACCSLALVVCWERISTYQNHLTDVAAGAALGGWMAFFATVFVAHLFVEVRVKRRPMPRNEQIYGYAGYYTRATYGY", "length": 305 }, "evidence": [ { "id": "MGI:1354945", "url": "https://alliancegenome.org/gene/MGI:1354945#orthology", "database": "AGR" }, { "id": "MGI:108412", "url": "https://alliancegenome.org/gene/MGI:108412#orthology", "database": "AGR" }, { "id": "MGI:1915166", "url": "https://alliancegenome.org/gene/MGI:1915166#orthology", "database": "AGR" }, { "id": "HGNC:9229", "url": "https://alliancegenome.org/gene/HGNC:9229#orthology", "database": "AGR" }, { "id": "HGNC:9230", "url": "https://alliancegenome.org/gene/HGNC:9230#orthology", "database": "AGR" }, { "id": "HGNC:9228", "url": "https://alliancegenome.org/gene/HGNC:9228#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-7425", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-7425#orthology", "database": "AGR" }, { "id": "RGD:621832", "url": "https://alliancegenome.org/gene/RGD:621832#orthology", "database": "AGR" }, { "id": "RGD:620454", "url": "https://alliancegenome.org/gene/RGD:620454#orthology", "database": "AGR" }, { "id": "RGD:628893", "url": "https://alliancegenome.org/gene/RGD:628893#orthology", "database": "AGR" }, { "id": "SGD:S000002911", "url": "https://alliancegenome.org/gene/SGD:S000002911#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VNU1-1", "protein_name": "Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein", "gene_name": "WUN-like", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSKYSKLARGFCDLLIWVALSVASVLLHKMGRPFRRGFFCGDETLSYPARDGTISSKVIIAIVLGVPNAVIVVVELFRQLPGGPLREAGGKRDSCRIAHRLGVLYRQVIFYLYGLAMVTFTTMLTKLCLGRLRPHFLAVCQPMLPDGSSCQDAQNLGRYIDSFTCSNANMTDYQFKELYQSFPSGHASMAMYAMLYLAIYLQAALSTRVSKLLKHLLQFLFVMFGWYVSLTRIIDYYHHWSDVLAGAALGVVFAWLTSAYVADLFAGKRWPKTGYSANTLRKPQVSPKSSTKSQAGGSTSGAGQPPALPAYTFGTLPYLAAHPAQAQAQYAQPYHNYGYVP", "length": 341 }, "evidence": [ { "id": "MGI:1354945", "url": "https://alliancegenome.org/gene/MGI:1354945#orthology", "database": "AGR" }, { "id": "MGI:108412", "url": "https://alliancegenome.org/gene/MGI:108412#orthology", "database": "AGR" }, { "id": "MGI:1915166", "url": "https://alliancegenome.org/gene/MGI:1915166#orthology", "database": "AGR" }, { "id": "HGNC:9229", "url": "https://alliancegenome.org/gene/HGNC:9229#orthology", "database": "AGR" }, { "id": "HGNC:9230", "url": "https://alliancegenome.org/gene/HGNC:9230#orthology", "database": "AGR" }, { "id": "HGNC:9228", "url": "https://alliancegenome.org/gene/HGNC:9228#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-7425", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-7425#orthology", "database": "AGR" }, { "id": "RGD:621832", "url": "https://alliancegenome.org/gene/RGD:621832#orthology", "database": "AGR" }, { "id": "RGD:620454", "url": "https://alliancegenome.org/gene/RGD:620454#orthology", "database": "AGR" }, { "id": "RGD:628893", "url": "https://alliancegenome.org/gene/RGD:628893#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VNU2", "url": "https://www.uniprot.org/uniprotkb/Q9VNU2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VNU2", "url": "https://www.uniprot.org/uniprotkb/Q9VNU2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "Q9VNU2", "url": "https://www.uniprot.org/uniprotkb/Q9VNU2" } ], "pmid": "" }, { "name": "phospholipid metabolic process", "id": "GO:0006644", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006644", "evidence": [ { "database": "UniProtKB", "id": "Q9VNU2", "url": "https://www.uniprot.org/uniprotkb/Q9VNU2" } ], "pmid": "" }, { "name": "phototransduction", "id": "GO:0007602", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007602", "evidence": [ { "database": "UniProtKB", "id": "Q9VNU2", "url": "https://www.uniprot.org/uniprotkb/Q9VNU2" } ], "pmid": "" }, { "name": "response to light intensity", "id": "GO:0009642", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009642", "evidence": [ { "database": 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The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
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The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
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The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. 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Treatment is symptomatic." }, { "id": "MONDO:0008495", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008495", "name": "alpha dense granule deficiency", "description": "" }, { "id": "MONDO:0008495", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008495", "name": "combined alpha-delta platelet storage pool deficiency", "description": "" }, { "id": "MONDO:0008495", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008495", "name": "platelet storage pool diseases", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "2223", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2223" } ] }, { "disease_id": "DOID:3753", "recommended_name": { "id": "DOID:3753", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3753", "name": "Hermansky-Pudlak syndrome", "description": "A syndrome characterized by oculocutaneous albinism, bleeding problems due to platelet storage pool defect, visual impairment and lysosomal accumulation of ceroid lipofuscin." }, "synonyms": [ { "id": "MONDO:0008748", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008748", "name": "Hermansky-Pudlak syndrome 1", "description": "Any Hermansky-Pudlak syndrome in which the cause of the disease is a mutation in the HPS1 gene." }, { "id": "MONDO:0008748", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008748", "name": "HPS1 Hermansky-Pudlak syndrome", "description": "" }, { "id": "MONDO:0008748", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008748", "name": "Hermansky-Pudlak syndrome 1", "description": "" }, { "id": "MONDO:0008748", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008748", "name": "Hermansky-Pudlak syndrome caused by mutation in HPS1", "description": "" }, { "id": "MONDO:0008748", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008748", "name": "Hermansky-Pudlak syndrome type 1", "description": "" }, { "id": "MONDO:0008748", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008748", "name": "HPS1", "description": "" }, { "id": "MIM:203300", "resource": "MIM", "url": "https://www.omim.org/entry/203300", "name": "Hermansky-Pudlak syndrome 1", "description": "Hermansky-Pudlak syndrome 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "3753", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3753" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VNX0", "url": "https://www.uniprot.org/uniprotkb/Q9VNX0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "NP_649372", "url": "https://www.uniprot.org/uniprotkb/Q9VNX0", "locus": { "chromosome": "3L", "start_pos": 21949866, "end_pos": 21942221, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0037142", "url": "https://www.ensemblgenomes.org/id/FBgn0037142" } ] } } ], "crossref": [ { "id": "FB:FBgn0037142", "url": "https://alliancegenome.org/gene/FB:FBgn0037142", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0037142", "url": "https://bgee.org/?page=gene&gene_id=FBgn0037142", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0037142", "url": "https://flybase.org/reports/FBgn0037142", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "40439", "url": "https://www.ncbi.nlm.nih.gov/gene/40439", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VNX0", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VNX0*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR017216", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017216", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029437", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029437", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029438", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029438", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG14562", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG14562", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MAPNYCP", "url": "https://omabrowser.org/oma/group/MAPNYCP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VNX0", "url": "https://www.orthodb.org/?gene=Q9VNX0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28633", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28633", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28633:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28633:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14761", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14761", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14763", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14763", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001262199", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262199", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VNX0", "url": "https://www.uniprot.org/uniprotkb/Q9VNX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VNX0-1", "url": "https://www.uniprot.org/uniprotkb/Q9VNX0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVKILQAYNFARQQTYALNGDILAASLIGNNRIAISSAEQFIEIYDIGAKQAQSEDHTRTAPEDVGQSNETAGESTTTAGDERTPSRSTLATVGEVVQLIYCEAGKYLLTLEKEQAGSPVHSSSTISCTSSSNSNTVCSEDDTKMFVRIYANFWKFPDSRLNELPITIRIASMTTPKTPLVESIDVIELPLRSPPELVQCCQTSGNIIVSSRDRIYLYEYTQCVHENTQPRFAFIDFLPFKFFVQLNFVPVRLCLAENVIACLSNRYCVAFKVVDALTSRASGGQDVSCLDNDYVGGDEPLSESLSLGSKASASGAGGGVVSSSHSQQSCDSDSLQSTSSAKPQVVMNGALPGRSPLDFNVAKLVNNAYGREFEPELRSQWDETTDYGAGKGQDDNLDITISPQRASDIKIKLVNEAKAMNVRGISGSSHLDDASVQYDVRKLLQICMKTSENQPRVLDIFRCMDLKAIYQRNSQEVDQEDDEYDMGNQQVPSAVTTFKHVNRRTLKSSQHQRCIGHALLVASSVDGFLYQFSAQGKWYSENEKPVASYSFTAPVIQVHINDYVVYAVTSESVETHTSRIGHKLFHNRFEYPSIGGLFPEESAPDVSSPIAVVGLAAFMHVQFVCVNREQLVLITNAALEQHKRRSMSEVPGTQVVAVKRNIAARLLAEAKAKHNSLLRSSSAVQSSTVANEWTLYNLEVPRVECVIEDLEGIAESYRSASSSNFFDLMEEAHVMLRISLTLQGERLGAEREQLLRKMFMANCRKLADFSIRSSKKEVYLQATGFYRMCQFHLVDIFNNYVQNFMDTEESVIPLELSGLIYTVKLFLLCLGTDRLKSAFLNQTVLPYFTPARVIQQGYKQVPISLEFLNMFIKHAPLEIAQIMLVSPVVADSISGELINYLKYLDKLSPDENLLLAVTACRMSNYLLAQEVVSKSTRRNLATALIRHKNVLFDDSTVIYQRRNQQQADSQALSLRARKSRRMAAKSKPAPVGTPAPSTIVSFSDFCETILLANEQPALLEAISDAFIHALCIEHSMTLDVILQLFLNYIASHIGQKGYQTSQKVFVNILQVYFYDLYDVSSSLQPQEIRSQTPPQLDDDYDEECSSSRAPSLHSEADAQSLSSSCASSAHEDRSASLSISGRQQRIVYDQLQEQQSSPFQKRNSNASLSQPQANDDVTATNLKGLKILFRMYMGRLKALSDLITDLQSADVEQQTSREEFINLRMECISYMVGMAPNYSPKPIIRNPNDPLAGKLIYVPFIPDYKLPDGEEYDRHIKGYIRPIPCLLERPQYLNRLPPFERSDFSYPNKDDGEFEVRFLSWHNELLTLSLKIQSLLASTKVDREIVSEFLAFIQKTPNLIGIDSFLVIVLPKNLAINYLLSFCPAFLWQYGKSCGFTPKHWESLLRKILSKQEALPNWKAHITEILNNLVAELSFEELLQCFPSEAIQNRNTAQYFATEFAETCILYENEELVFKNPDLKEGHRDHMPMDNIDEDNVFELTLRKAVAKQRSIALRSMIESTGTQLFDATSNPMYNL", "length": 1536, "header": "tr|Q9VNX0-1|Q9VNX0_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=NP_649372 PE=1 SV=2 CANONICAL=Q9VNX0-1" }, "isoforms": [ { "isoform_ac": "Q9VNX0-1", "url": "https://www.uniprot.org/uniprotkb/Q9VNX0/entry#Q9VNX0-1", "sequence": { "sequence": "MVKILQAYNFARQQTYALNGDILAASLIGNNRIAISSAEQFIEIYDIGAKQAQSEDHTRTAPEDVGQSNETAGESTTTAGDERTPSRSTLATVGEVVQLIYCEAGKYLLTLEKEQAGSPVHSSSTISCTSSSNSNTVCSEDDTKMFVRIYANFWKFPDSRLNELPITIRIASMTTPKTPLVESIDVIELPLRSPPELVQCCQTSGNIIVSSRDRIYLYEYTQCVHENTQPRFAFIDFLPFKFFVQLNFVPVRLCLAENVIACLSNRYCVAFKVVDALTSRASGGQDVSCLDNDYVGGDEPLSESLSLGSKASASGAGGGVVSSSHSQQSCDSDSLQSTSSAKPQVVMNGALPGRSPLDFNVAKLVNNAYGREFEPELRSQWDETTDYGAGKGQDDNLDITISPQRASDIKIKLVNEAKAMNVRGISGSSHLDDASVQYDVRKLLQICMKTSENQPRVLDIFRCMDLKAIYQRNSQEVDQEDDEYDMGNQQVPSAVTTFKHVNRRTLKSSQHQRCIGHALLVASSVDGFLYQFSAQGKWYSENEKPVASYSFTAPVIQVHINDYVVYAVTSESVETHTSRIGHKLFHNRFEYPSIGGLFPEESAPDVSSPIAVVGLAAFMHVQFVCVNREQLVLITNAALEQHKRRSMSEVPGTQVVAVKRNIAARLLAEAKAKHNSLLRSSSAVQSSTVANEWTLYNLEVPRVECVIEDLEGIAESYRSASSSNFFDLMEEAHVMLRISLTLQGERLGAEREQLLRKMFMANCRKLADFSIRSSKKEVYLQATGFYRMCQFHLVDIFNNYVQNFMDTEESVIPLELSGLIYTVKLFLLCLGTDRLKSAFLNQTVLPYFTPARVIQQGYKQVPISLEFLNMFIKHAPLEIAQIMLVSPVVADSISGELINYLKYLDKLSPDENLLLAVTACRMSNYLLAQEVVSKSTRRNLATALIRHKNVLFDDSTVIYQRRNQQQADSQALSLRARKSRRMAAKSKPAPVGTPAPSTIVSFSDFCETILLANEQPALLEAISDAFIHALCIEHSMTLDVILQLFLNYIASHIGQKGYQTSQKVFVNILQVYFYDLYDVSSSLQPQEIRSQTPPQLDDDYDEECSSSRAPSLHSEADAQSLSSSCASSAHEDRSASLSISGRQQRIVYDQLQEQQSSPFQKRNSNASLSQPQANDDVTATNLKGLKILFRMYMGRLKALSDLITDLQSADVEQQTSREEFINLRMECISYMVGMAPNYSPKPIIRNPNDPLAGKLIYVPFIPDYKLPDGEEYDRHIKGYIRPIPCLLERPQYLNRLPPFERSDFSYPNKDDGEFEVRFLSWHNELLTLSLKIQSLLASTKVDREIVSEFLAFIQKTPNLIGIDSFLVIVLPKNLAINYLLSFCPAFLWQYGKSCGFTPKHWESLLRKILSKQEALPNWKAHITEILNNLVAELSFEELLQCFPSEAIQNRNTAQYFATEFAETCILYENEELVFKNPDLKEGHRDHMPMDNIDEDNVFELTLRKAVAKQRSIALRSMIESTGTQLFDATSNPMYNL", "length": 1536, "header": "tr|Q9VNX0-1|Q9VNX0_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=NP_649372 PE=1 SV=2 CANONICAL=Q9VNX0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VNX0", "url": "https://www.uniprot.org/uniprotkb/Q9VNX0" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VNX0", "url": "https://www.uniprot.org/uniprotkb/Q9VNX0" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VNX0", "url": "https://www.uniprot.org/uniprotkb/Q9VNX0" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VNX0", "url": "https://www.uniprot.org/uniprotkb/Q9VNX0" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VNX0", "url": "https://www.uniprot.org/uniprotkb/Q9VNX0" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VNX0", "url": "https://www.uniprot.org/uniprotkb/Q9VNX0" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VNX0", "url": "https://www.uniprot.org/uniprotkb/Q9VNX0" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VNX0", "url": "https://www.uniprot.org/uniprotkb/Q9VNX0" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VNX0", "url": "https://www.uniprot.org/uniprotkb/Q9VNX0" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VNX0", "url": "https://www.uniprot.org/uniprotkb/Q9VNX0" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VNX0", "url": "https://www.uniprot.org/uniprotkb/Q9VNX0" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG14562", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG14562", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4IZE2-1", "protein_name": "BLOC-2 complex member HPS3", "gene_name": "hps3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVHVYNCHPFAAQRIVSAEQEPGLVCCGGGALFVVSAGGCKIEAFDLQREESPVICRFSCAGTVLSLQHSAVGDYLVTIEEKNNATYLRAYTNWRYQAVEKTRVGVRLLGHLLRGSSFRGAPKEQMEIIEIPLFEPPLCVACCSLTGDLLVGSAKSLVVFSLKRQTLSEQLSVLDFERVLILHIQGWSPSQVAFCAGYLALQTELEVLVIKLVQQQKSAQTAEENALLPVDIMVETSLEDDAEMKKDGFSPLHEQEDFFVFPKHQEMLGSEAQHCGITLVPECTAMDSESRGETTVVYVLFRRFAPDFFQGCSVEETRLHSLQLHPIFTGKQEESSISRCGDPDCMFVFFSLPNTGYMYSLKSSVELVSTYQYPEKAHQAVLSDQFLYVITRNALQCFTVRCSAVAARVQDPYIDTTMKACPPFSMEVCALRIQLFIGLKVLCQDGDHIVLLTAADVDSKENTERPARKNTSRKSSVCKSTEAPDSAHGWNLYVISSVSTLQLYREIVEYSKRYEQSNPCSQSCVHLLSEAHLLLRSALLKLQNGPAEEKQELLEAFQESCAHLGDCFSRFDKKDCHLALPYYKMSGLTVTDVIQRNVSMSGVSSGYGRGFIFFLKHSLYEETVEELSKDVADKVLEIFSVAEPAQLPHVVCCSSMLNADPDGAGALLEQLEASGAPSITLALCRASLALRTGDRHTYSQQMERHAEMLQVYGFIEEPRLLLHGRGVGLMPTLLAQQLRDSQDGLLVAALVALHENSRISLEDAHLFFQELCKDRLEPDSSPQLLVDFWESLLVASSRESTIQELLFRLVSVYISRITCSHPSGCKALKTADDLINSCSHYGMLYPWVSILTPNLYHDQQEDLLKLQSLLCGPTLQVSSILPLLEPLSDSDDPGLSVHVLCSTKLGQHEDSIHRLLDRCPQAIIPYAQHQLHHHTLCLWWQKLFPEVCDRIRKTGNDNTILLSALKETLIVAARELTPLEFLDLLPDDGTAHFFLPHLLECCQ", "length": 1003 }, "evidence": [ { "id": "RGD:1310548", "url": "https://alliancegenome.org/gene/RGD:1310548#orthology", "database": "AGR" }, { "id": "MGI:2153839", "url": "https://alliancegenome.org/gene/MGI:2153839#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061110-115", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061110-115#orthology", "database": "AGR" }, { "id": "HGNC:15597", "url": "https://alliancegenome.org/gene/HGNC:15597#orthology", "database": "AGR" }, { "id": "FB:FBgn0037142", "url": "https://alliancegenome.org/gene/FB:FBgn0037142#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZGG8-1", "protein_name": "Hermansky-Pudlak syndrome 3 protein homolog", "gene_name": "Hps3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRLYNLHPFGSQQVVPCQREPEQFCCGGSDALFVASGCKVEAFAVQGAELSRQRCTFSTLGRVLRMAYSEAGDYLVAIEEKNKTVFLRAYVNWRSKRNDNSRVCIRMVGHKMEASFCESFRDQMSIIEMPMSEAPLCISCCPVKGDLLVGCTKKLVLFTLKYDVVNEEFSMLNFERSLIIHINNITPVEISFCVGYVAVMADLEVLLLKLESDPIHGEGVNHHPQESINPLEQTEDVSNETSQLESEDFVICLKPLELFGEKCKQSGISVKLESTGLEDEKVKYLHVQHLLYRRFAPDISFYGLSDNIKLHSLQLLPIHQTGFHPDEKDLSQKKEVPSLFCFFSLPHAGYLYMVVKSVTLLSVYWYPEKSQQAVLTPQFLHVITSQSLQCFTVRCSAAVAHEEDLYMDTTLKACPPVSMDVCALRIQLFIGLKAICHFKNHIILLTKAEPEDIPERRESPKRLLSRKDASVKSRIPHVAEAGWNLYIVNTTAPVQLYKEMVDYSNSYKTVKTESCLHLLSEAHLLVRAALMDVSQLEPAEKAELLEAFKESCGHLGDCYSRLNTEQAHLALPYYKMSGLSLAEVLARVEWTEGNESQKYERGLIFYINHSLYENLDEELSEELAGKVAQIFHVAEPKQLPHVLSSPSMKNIDPLIALHYLRKLDTCGASPVLVTLTKAAVALKMGNLDMYRNEMKSHSEMQLVYGFILEPRLLIQQWKGQIVPTELAIDLKETQPGLLVASVLGLQKNGKIGIEEADSFFKVLCGKDEDMVPQLLVDFWEAQLVACLPDVVLEELFFKLISQYVWRLSKRHCPDTLPLRTAEDLINACSHYGLVYPWVHVLMTSDSLADKNYTEDLLKLQSLICSPSLDIVSVIPYLEPLSEDTVAGLSAQVLCHTRLQEYEKCIDTLLERCPEAVIAYANRELKEEHWILWWKKLLPELCHRVKCGGDRYHLHLSLLKETLSVVAVGLDLRDFLNVLPEDGVAAFFLPYLLFCSRKKSLT", "length": 1002 }, "evidence": [ { "id": "RGD:1310548", "url": "https://alliancegenome.org/gene/RGD:1310548#orthology", "database": "AGR" }, { "id": "MGI:2153839", "url": "https://alliancegenome.org/gene/MGI:2153839#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061110-115", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061110-115#orthology", "database": "AGR" }, { "id": "HGNC:15597", "url": "https://alliancegenome.org/gene/HGNC:15597#orthology", "database": "AGR" }, { "id": "FB:FBgn0037142", "url": "https://alliancegenome.org/gene/FB:FBgn0037142#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q91VB4-1", "protein_name": "BLOC-2 complex member HPS3", "gene_name": "Hps3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVRLYNLHPFGSQQVVPCQWEPEQVCCGGSDALFVAAGCKVEAFAVQGEELCRQRCAFSTLGRVLRMAYSEAGDYLVAIEEKNKTIFLRAYVNWRSKRSDNSRVCIRMVGHNVEASFCESFRDQMSIIEMPMSEAPLCFSCCPVKGDLLVGCTNKLVLFTLKYDIINEEFSILNFERSLIIHIDNITPVEISFCVGYVAVMSDLEVLLLKLESDPIHGESVDHHPQETSNPLKEAEGVSNETSQLESEDFVICLKPMELIGEKCEQSGISVKLESTGLEDEKVKYLRVRHLLYRRFAPDISSYVLSDNIKLHSLQLLPIHQSGFHPDENDLSPKKEMPNLFCFFSLPHVGYLYMVVKSVELMSVYWYPEKSQQAVLTPQFLHVITSQSLQCFTVRCSAAVAHEEDLYMDTTLKACPPVSMDVCALRIQLFIGLKAICHFKNHIILLTKAEPEAIPERRESPKKLISRKDASVRSGTPHVAEAAWNLYLVNTTAPVQLYKEMVDYSNSYKTVKTESCLHLLSEAHLLVRAALMDGSQLEPAEKAELLEAFKESCGHLGDCYSRLTTEQSHLALPYYKMSGLSLAEVLARVDWTEESESQKYERGLVFYINHSLYENLDEELSKELAAKVAQIFHMAEPKQLPHVLSSPSMKNIDPLTALHYLRKLDSCGVSPVLVTLTKAAVALKMGDLDMYRNEMKSHSEMKLVYGFILEPRLLIQQWKGQIVPTELAIDLKETQPGLLVASVLGLQKNDKIGIVETDSFFKVLCGKDEDAVPQLLIDFWEAQLVACLPNVVLEELFFKLISQYVWRLSERRCPDTVPLRTAEDLINACSHYGLVNPWVHVLTTSDSLADKNYTDDLLKLQSLICSPSLDVASIIPFLEPLSEDTVAGLSTHALCHTRLQEYEQCIDTLLERCPEAVIAYANQELKEDHWILWWKKLLPELCQRVKSGGERSHLHLSLLKETLSVIAVGLDLRDFLNVLPEDGAAAFFLPYLLFCSRKKSLT", "length": 1002 }, "evidence": [ { "id": "RGD:1310548", "url": "https://alliancegenome.org/gene/RGD:1310548#orthology", "database": "AGR" }, { "id": "MGI:2153839", "url": "https://alliancegenome.org/gene/MGI:2153839#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061110-115", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061110-115#orthology", "database": "AGR" }, { "id": "HGNC:15597", "url": "https://alliancegenome.org/gene/HGNC:15597#orthology", "database": "AGR" }, { "id": "FB:FBgn0037142", "url": "https://alliancegenome.org/gene/FB:FBgn0037142#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q969F9-1", "protein_name": "BLOC-2 complex member HPS3", "gene_name": "HPS3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVQLYNLHPFGSQQVVPCKLEPDRFCGGGRDALFVAAGCKVEAFAVAGQELCQPRCAFSTLGRVLRLAYSEAGDYLVAIEEKNKATFLRAYVNWRNKRTENSRVCIRMIGHNVEGPFSKAFRDQMYIIEMPLSEAPLCISCCPVKGDLLVGCTNKLVLFSLKYQIINEEFSLLDFERSLIIHIDNITPVEVSFCVGYVAVMSDLEVLIVKLESGPKNGERVHHHPHKTNNRIRRTEEGISNEISQLESDDFVICQKPLELLGEKSEQSGLSVTLESTGLADEKRKYSHFQHLLYRRFAPDISSYVLSDDIKLHSLQLLPIYQTGSLTSDGKNLSQEKELLSLFCFFSLPHVGYLYMVVKSVELMSVYQYPEKSQQAVLTPQFLHVITSNNLQCFTVRCSAAAAREEDPYMDTTLKACPPVSMDVCALRIQLFIGLKAICHFKNHIILLTKAEPEAIPERRQSPKRLLSRKDTSVKIKIPPVAEAGWNLYIVNTISPVQLYKEMVDYSNTYKTVKTQSCIHLLSEAHLLVRAALMDASQLEPGEKAELLEAFKESCGHLGDCYSRLDSQHSHLTLPYYKMSGLSMAEVLARTDWTVEDGLQKYERGLIFYINHSLYENLDEELNEELAAKVVQMFYVAEPKQVPHILCSPSMKNINPLTAMSYLRKLDTSGFSSILVTLTKAAVALKMGDLDMHRNEMKSHSEMKLVCGFILEPRLLIQQRKGQIVPTELALHLKETQPGLLVASVLGLQKNNKIGIEEADSFFKVLCAKDEDTIPQLLVDFWEAQLVACLPDVVLQELFFKLTSQYIWRLSKRQPPDTTPLRTSEDLINACSHYGLIYPWVHVVISSDSLADKNYTEDLSKLQSLICGPSFDIASIIPFLEPLSEDTIAGLSVHVLCRTRLKEYEQCIDILLERCPEAVIPYANHELKEENRTLWWKKLLPELCQRIKCGGEKYQLYLSSLKETLSIVAVELELKDFMNVLPEDGTATFFLPYLLYCSRKKPLT", "length": 1004 }, "evidence": [ { "id": "RGD:1310548", "url": "https://alliancegenome.org/gene/RGD:1310548#orthology", "database": "AGR" }, { "id": "MGI:2153839", "url": "https://alliancegenome.org/gene/MGI:2153839#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061110-115", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061110-115#orthology", "database": "AGR" }, { "id": "HGNC:15597", "url": "https://alliancegenome.org/gene/HGNC:15597#orthology", "database": "AGR" }, { "id": "FB:FBgn0037142", "url": "https://alliancegenome.org/gene/FB:FBgn0037142#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VNX0", "url": "https://www.uniprot.org/uniprotkb/Q9VNX0" } ], "pmid": "" }, { "name": "BLOC-2 complex", "id": "GO:0031084", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031084", "evidence": [ { "database": "UniProtKB", "id": "Q9VNX0", "url": "https://www.uniprot.org/uniprotkb/Q9VNX0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "compound eye pigmentation", "id": "GO:0048072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048072", "evidence": [ { "database": "UniProtKB", "id": "Q9VNX0", "url": "https://www.uniprot.org/uniprotkb/Q9VNX0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1165, "end_pos": 1167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1237, "end_pos": 1239, "annotation": "n_glycosylation_sequon" }, { "start_pos": 69, "end_pos": 71, "annotation": "n_glycosylation_sequon" }, { "start_pos": 841, "end_pos": 843, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VNX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VNX0" }, { "id": "PF14763", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14763" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BLOC-2 complex member HPS3 C-terminal", "eco_id": "ECO_0000259", "start_pos": 714, "end_pos": 805, "start_aa": "Ala", "end_aa": "Met", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q9VNX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VNX0" }, { "id": "PF14761", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14761" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BLOC-2 complex member HPS3 N-terminal", "eco_id": "ECO_0000259", "start_pos": 140, "end_pos": 278, "start_aa": "Glu", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1165, "end_pos": 1167 }, { "start_pos": 1237, "end_pos": 1239 }, { "start_pos": 69, "end_pos": 71 }, { "start_pos": 841, "end_pos": 843 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VP67-1", "uniprot_ac": "Q9VP67", "uniprot_id": "Q9VP67_DROME", "mass": { "chemical_mass": 62400.0, "monoisotopic_mass": 62400.0 }, "refseq": { "ac": "NP_649291", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649291" }, "gene_names": [ { "name": "Dmel\\CG10510", "type": "recommended", "evidence": [ { "id": "Q9VP67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VP67" } ] }, { "name": "CG10510", "type": "synonym", "evidence": [ { "id": "NP_649291", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649291" }, { "id": "Q9VP67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VP67" } ] }, { "name": "Dmel\\CG10510", "type": "synonym", "evidence": [ { "id": "NP_649291", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649291" } ] }, { "name": "Dmel_CG10510", "type": "synonym", "evidence": [ { "id": "Q9VP67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VP67" } ] } ], "protein_names": [ { "name": "Dynein regulatory complex subunit 2", "type": "recommended", "evidence": [ { "id": "Q9VP67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VP67/entry#names_and_taxonomy" } ] }, { "name": "CG10510-PA", "type": "synonym", "evidence": [ { "id": "NP_649291", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649291" } ] }, { "name": "Coiled-coil domain-containing protein 65", "type": "synonym", "evidence": [ { "id": "Q9VP67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VP67/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_649291", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649291" } ] } ], "function": [ { "annotation": "Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with DRC1 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules.", "evidence": [ { "database": "UniProtKB", "id": "Q9VP67", "url": "https://www.uniprot.org/uniprotkb/Q9VP67#function" }, { "database": "UniProtKB", "id": "ARBA00045865", "url": "https://www.uniprot.org/uniprotkb/ARBA00045865#function" } ] } ], "disease": [ { "disease_id": "DOID:0110611", "recommended_name": { "id": "DOID:0110611", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110611", "name": "primary ciliary dyskinesia 27", "description": "A primary ciliary dyskinesia that is characterized by autosomal recessive inheritance with neonatal respiratory distress, recurrent upper and lower airway disease, and bronchiectasis and has_material_basis_in homozygous mutation in the CCDC65 gene on chromosome 12q13." }, "synonyms": [ { "id": "DOID:0110611", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110611", "name": "CILD27", "description": "" }, { "id": "DOID:0110611", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110611", "name": "primary ciliary dyskinesia 27 without situs inversus", "description": "" }, { "id": "MONDO:0014215", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014215", "name": "primary ciliary dyskinesia 27", "description": "Any primary ciliary dyskinesia in which the cause of the disease is a mutation in the CCDC65 gene." }, { "id": "MONDO:0014215", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014215", "name": "CCDC65 primary ciliary dyskinesia", "description": "" }, { "id": "MONDO:0014215", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014215", "name": "CILD27", "description": "" }, { "id": "MONDO:0014215", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014215", "name": "ciliary dyskinesia, primary, type 27", "description": "" }, { "id": "MONDO:0014215", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014215", "name": "primary ciliary dyskinesia caused by mutation in CCDC65", "description": "" }, { "id": "MONDO:0014215", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014215", "name": "primary ciliary dyskinesia type 27", "description": "" }, { "id": "MONDO:0014215", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014215", "name": "ciliary dyskinesia, primary, 27", "description": "" }, { "id": "MIM:615504", "resource": "MIM", "url": "https://www.omim.org/entry/615504", "name": "Ciliary dyskinesia, primary, 27", "description": "Ciliary dyskinesia, primary, 27" } ], "unlinked_id_list": [], "evidence": [ { "id": "0110611", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110611" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VP67", "url": "https://www.uniprot.org/uniprotkb/Q9VP67" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG10510", "url": "https://www.uniprot.org/uniprotkb/Q9VP67", "locus": { "chromosome": "3L", "start_pos": 21208148, "end_pos": 21210084, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0037059", "url": "https://www.ensemblgenomes.org/id/FBgn0037059" } ] } } ], "crossref": [ { "id": "FB:FBgn0037059", "url": "https://alliancegenome.org/gene/FB:FBgn0037059", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0037059", "url": "https://bgee.org/?page=gene&gene_id=FBgn0037059", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0037059", "url": "https://flybase.org/reports/FBgn0037059", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "40341", "url": "https://www.ncbi.nlm.nih.gov/gene/40341", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VP67", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VP67*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR039505", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039505", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039750", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039750", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG10510", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG10510", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VRRMTHM", "url": "https://omabrowser.org/oma/group/VRRMTHM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VP67", "url": "https://www.orthodb.org/?gene=Q9VP67", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21625", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21625", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21625:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21625:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14772", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14772", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_649291", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649291", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VP67", "url": "https://www.uniprot.org/uniprotkb/Q9VP67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VP67-1", "url": "https://www.uniprot.org/uniprotkb/Q9VP67-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEILARLTRVSENYLQELEEEPEPQGPPKLTKAQKKAAKKEAKRLAMIEEKRLIMRDALMRELEMGKHMEEKGNEEWHEMCREIKIKELNEEMRAWGERSERNIQAKNDHIKMLLDDMAQTQDQHVRCYSKTVELIDHIRDCFHVMLGGVKSMYDQQADEMLRDYYEEVRRRTEEVEAMKTNSENIIHATNITTRDQLKEDYTIYLEQRDDRVNTEIENRFKIRDQIVRRMTHMQQQLNDFVESLRSTELDAHKYEKIHWLTERQAAFMEESRKLNAEESKYINMQAELQREMVRMDAENNSTLNDLRLEFQYFTNVRKKIELNQEMDREITHEKLRILTGECYELTKQMEKHVKSGELLLALSITCRKLQTESEKVILGGEVFDETEVDVDEYFKLQTLNLKDHVDMTEEELVELNKSLRNFWRRQAMAEAQNLLMLEEKRRLTEDNQRLIDFIKSMSVTEDPEELRTAMHVSSPTQPMPPKLFETKCQEFKSRKVVHSPTAHKEAKWEAEATLNEVILDF", "length": 523, "header": "tr|Q9VP67-1|Q9VP67_DROME Isoform 1 of Dynein regulatory complex subunit 2 OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG10510 PE=3 SV=1 CANONICAL=Q9VP67-1" }, "isoforms": [ { "isoform_ac": "Q9VP67-1", "url": "https://www.uniprot.org/uniprotkb/Q9VP67/entry#Q9VP67-1", "sequence": { "sequence": "MAEILARLTRVSENYLQELEEEPEPQGPPKLTKAQKKAAKKEAKRLAMIEEKRLIMRDALMRELEMGKHMEEKGNEEWHEMCREIKIKELNEEMRAWGERSERNIQAKNDHIKMLLDDMAQTQDQHVRCYSKTVELIDHIRDCFHVMLGGVKSMYDQQADEMLRDYYEEVRRRTEEVEAMKTNSENIIHATNITTRDQLKEDYTIYLEQRDDRVNTEIENRFKIRDQIVRRMTHMQQQLNDFVESLRSTELDAHKYEKIHWLTERQAAFMEESRKLNAEESKYINMQAELQREMVRMDAENNSTLNDLRLEFQYFTNVRKKIELNQEMDREITHEKLRILTGECYELTKQMEKHVKSGELLLALSITCRKLQTESEKVILGGEVFDETEVDVDEYFKLQTLNLKDHVDMTEEELVELNKSLRNFWRRQAMAEAQNLLMLEEKRRLTEDNQRLIDFIKSMSVTEDPEELRTAMHVSSPTQPMPPKLFETKCQEFKSRKVVHSPTAHKEAKWEAEATLNEVILDF", "length": 523, "header": "tr|Q9VP67-1|Q9VP67_DROME Isoform 1 of Dynein regulatory complex subunit 2 OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG10510 PE=3 SV=1 CANONICAL=Q9VP67-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VP67", "url": "https://www.uniprot.org/uniprotkb/Q9VP67" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VP67", "url": "https://www.uniprot.org/uniprotkb/Q9VP67" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VP67", "url": "https://www.uniprot.org/uniprotkb/Q9VP67" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VP67", "url": "https://www.uniprot.org/uniprotkb/Q9VP67" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VP67", "url": "https://www.uniprot.org/uniprotkb/Q9VP67" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VP67", "url": "https://www.uniprot.org/uniprotkb/Q9VP67" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VP67", "url": "https://www.uniprot.org/uniprotkb/Q9VP67" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VP67", "url": "https://www.uniprot.org/uniprotkb/Q9VP67" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VP67", "url": "https://www.uniprot.org/uniprotkb/Q9VP67" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VP67", "url": "https://www.uniprot.org/uniprotkb/Q9VP67" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VP67", "url": "https://www.uniprot.org/uniprotkb/Q9VP67" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG10510", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG10510", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q5XIJ8-1", "protein_name": "Dynein regulatory complex subunit 2", "gene_name": "Drc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKKGKKPKLPLTDEEQLILFQQKLLADEEAAKKKERLLTQFLKDKLAKEEHNSSLNLNKINTQWRTVLREVKTRELHKDIEILSQIFERVVDCKDSVIKSLARDLTEAEEQYAHALRGHLHNVDQLLTLQRRRLSLLEENYNMELEVLTKEFETERKAILDHHDKEIHYLHDVFMAMEQNYVDSEYESKLEFQSMWDDLKNKNLEEKHFLRLQLENVVEDLWRRFQDALKNYTDATEDRKIAFETLKVKDEKSSKEIEVQMKKIQRLQEAISALKGKIVAHSREGEWQNQCIRNDKELVHVQLRKLKIQRTQARTESQENLVKLTLESNATLKALKKVVEKGEKILKLAEICRKFETEEEKVLPFYSSALTPEEQEEVEIQSQEEITEDLAKIMMDYLGMENFWKRYNKVKLEVLSLQHRRLQLLDISSKLREMLKQYLDGISVSDEVLSRLNPLFIVNHKSNLPQLPPSAAQPGGDRGPGGDRRLTYNVIEAAHIASHIL", "length": 502 }, "evidence": [ { "id": "RGD:1595842", "url": "https://alliancegenome.org/gene/RGD:1595842#orthology", "database": "AGR" }, { "id": "MGI:2146001", "url": "https://alliancegenome.org/gene/MGI:2146001#orthology", "database": "AGR" }, { "id": "HGNC:29937", "url": "https://alliancegenome.org/gene/HGNC:29937#orthology", "database": "AGR" }, { "id": "FB:FBgn0037059", "url": "https://alliancegenome.org/gene/FB:FBgn0037059#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6DHI2-1", "protein_name": "Dynein regulatory complex subunit 2", "gene_name": "drc2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPKKAGKKAGGKLAGLTEEERLLYMQQKAQAEEEIAKRKEDMLTHFLKDKLQKEEKNTVLNLHKLRQQWRAVLTQTKIAELRNDMSVLSQTFERVLDYKDNIIRSLQVDLSERELQSELKRSSHLHNVDCLLEIHKSRLAQLEFNFKSSLVELSSEYNTEREQILSQHQQECVDLDNVMFSMEKHYSDLDGEAKRDYQSTRNQIKKRNFDDKQAVKEQMDGVVEKLWQDQQQVLNHYNESTRDKIITTDDLMNKDVQSAKEIDSLKKHIQKLQDSISTFRGQLSSGQTDKTAEQLRSERDELAQEVQHFRVQLNAAQAIRKKHITKLTVQSNDATKKLQEIVARGERLLRQCEMCCKLETEHEKVLPFYKSSLSEEEQKQEKAKAMESSNEKLTQLMHDYSPLAKFWQRYNKVELDCLCVKREKLLLLQENERLRLFLKQYLDEVSVSDESFRQQKLLVVSSPALQDTAATDRHQQKRHVVQEAACIVQKQL", "length": 492 }, "evidence": [ { "id": "RGD:1595842", "url": "https://alliancegenome.org/gene/RGD:1595842#orthology", "database": "AGR" }, { "id": "MGI:2146001", "url": "https://alliancegenome.org/gene/MGI:2146001#orthology", "database": "AGR" }, { "id": "HGNC:29937", "url": "https://alliancegenome.org/gene/HGNC:29937#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8IXS2-1", "protein_name": "Dynein regulatory complex subunit 2", "gene_name": "DRC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPKKEKMAKTPLSDEKQLLLFQQKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSALNLNKINTQWRTVLREVKTRELHKDIEILSQTFERVVDCKDNVIKSLAKDLSEAEEQYAHALRSHLHNVDQLLALQRHRLSLLEESYNMELEALTKEFETERKTIIDQHEKEIHYLQDIFMAMEQNYIDSEYESKLEFQSMWNDLKNMNLEEKHFLRLHLENRVEDLWRKFQDVLKNYTDATEDRKAAFETLQVKDEKSSKEIEVQMKKIQKLQDAITISKGKIMIHSRESEDENRYIRNDKELVLVQLRKLKAQRTQARAASQKNLVRLTLESNATLKALRKIVDKGEKILKLAEICRKFETEEEKVLPFYSSVLTPKEQEGIQKNNLEELTEELTKVMVDYIGMENFWKRYNKVKLEQLSLQHRRAQLLDINGKLREMLKQYLDGISVSDEVLSQLNPLFIVNYQSNLLQPLSIRIAHPGDKQHPTT", "length": 484 }, "evidence": [ { "id": "RGD:1595842", "url": "https://alliancegenome.org/gene/RGD:1595842#orthology", "database": "AGR" }, { "id": "MGI:2146001", "url": "https://alliancegenome.org/gene/MGI:2146001#orthology", "database": "AGR" }, { "id": "HGNC:29937", "url": "https://alliancegenome.org/gene/HGNC:29937#orthology", "database": "AGR" }, { "id": "FB:FBgn0037059", "url": "https://alliancegenome.org/gene/FB:FBgn0037059#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VHI7-1", "protein_name": "Dynein regulatory complex subunit 2", "gene_name": "Drc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSKKGKKPKLPKAPLSEEDQLLIFQQKMLADEEAAKKKERLLTQFLKDKLAKEEHNSALNLNKINTQWRTILREVKTRELHQDIEILSQTFERVVDCKDSVIKSLAKDLTEAEEQYAHALRSHLHNIDQLLTLQRRRLGLLEENYNMELEVLTKEFETERKLIIDHHEKEMHYLQDVFMAMEQNYIDSEYESKLEFQSMWDDLKNKNLEEKHFLRLQLENIVEDLWRRFQDALKNYTDATEDRKIAFEYLKVKDEKSSKEIETQMKKIQKLQETIGILKGKIVAHSREGEWQNQCIRNNKELVHVQLRKLKVQRTQARTLSQENLVKLTLESNATLKALKKVVEKGEKILKLAEICRKFETEEEKVLPFYSSVLTPEEQEEAKLQNPEDITEDLAKIMMDYAGMENFWKRYNKVKLEVLSLQHRRLQLLDISSKLREMLKQYLDGISVSDEVLSHLNPLFVVNHRSNLPQLPPPSAQPVYNVIEAAHIASHIL", "length": 493 }, "evidence": [ { "id": "RGD:1595842", "url": "https://alliancegenome.org/gene/RGD:1595842#orthology", "database": "AGR" }, { "id": "MGI:2146001", "url": "https://alliancegenome.org/gene/MGI:2146001#orthology", "database": "AGR" }, { "id": "HGNC:29937", "url": "https://alliancegenome.org/gene/HGNC:29937#orthology", "database": "AGR" }, { "id": "FB:FBgn0037059", "url": "https://alliancegenome.org/gene/FB:FBgn0037059#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9W212-1", "protein_name": "Dynein regulatory complex subunit 2", "gene_name": "CG13522", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGKKGKGKGNKLANMSEEERARYLQMRADMEEETRRRKMQLISMYMKNKLKREDAFGRLNMAKINQEWRSILRQVKIQELRREIVDVESFFQEALKRKDQVIHRLIAHIESTEDMYANLQQSHMENITRIVDTHRDRIEFFRTIYEDDKQAVLSQWEQDSAAFKEMHAQKQQQLECVFYQLEENTDGGIRDNHERFLDRCEDLKSGMQLQLEQITSRGEARLEKLWQEYQGVLAGYCQHIEGFYSEYVDLKQRDEEAALQISQQTHEIEHLVDQLTNLRLVSEEFYIKQQGQLEQRQAIKQQLTERLRELRTCVEQEVARDHQLFKLMSVESYHALEFLQETVAKGETLAQLSAVCAKMETQRERMFQLPEISKEIIEIRDIEDQGNGSLTDPATDLLKDEVAVVPQMESFWRRVNNVAVDVACLKQQKRRLEAENSQLKTQLQDYLVNLNIANGSNSHVHSYLARRPKSMSVDRVSRLQLQPKLVKSAQPTGRRPAAPTPPTFHLHPGRSRAPAFEANLSNVVLSRTLARGKMNLARME", "length": 540 }, "evidence": [ { "id": "RGD:1595842", "url": "https://alliancegenome.org/gene/RGD:1595842#orthology", "database": "AGR" }, { "id": "MGI:2146001", "url": "https://alliancegenome.org/gene/MGI:2146001#orthology", "database": "AGR" }, { "id": "HGNC:29937", "url": "https://alliancegenome.org/gene/HGNC:29937#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { 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Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VP87", "url": "https://www.uniprot.org/uniprotkb/Q9VP87" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VP87", "url": "https://www.uniprot.org/uniprotkb/Q9VP87" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VP87", "url": "https://www.uniprot.org/uniprotkb/Q9VP87" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VP87", "url": "https://www.uniprot.org/uniprotkb/Q9VP87" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VP87", "url": "https://www.uniprot.org/uniprotkb/Q9VP87" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VP87", "url": "https://www.uniprot.org/uniprotkb/Q9VP87" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VP87", "url": "https://www.uniprot.org/uniprotkb/Q9VP87" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VP87", "url": "https://www.uniprot.org/uniprotkb/Q9VP87" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VP87", "url": "https://www.uniprot.org/uniprotkb/Q9VP87" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VPA2-1", "uniprot_ac": "Q9VPA2", "uniprot_id": "Q9VPA2_DROME", "mass": { "chemical_mass": 50666.0, "monoisotopic_mass": 50666.0 }, "refseq": { "ac": "NP_001262130", "name": "uncharacterized protein, isoform C", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262130" }, "gene_names": [ { "name": "Dmel\\CG11456", "type": "recommended", "evidence": [ { "id": "Q9VPA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPA2" } ] }, { "name": "CG11456", "type": "synonym", "evidence": [ { "id": "NP_001262130", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262130" }, { "id": "Q9VPA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPA2" } ] }, { "name": "Dmel\\CG11456", "type": "synonym", "evidence": [ { "id": "NP_001262130", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262130" } ] }, { "name": "Dmel_CG11456", "type": "synonym", "evidence": [ { "id": "Q9VPA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPA2" } ] } ], "protein_names": [ { "name": "C2H2-type domain-containing protein", "type": "recommended", "evidence": [ { "id": "Q9VPA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPA2/entry#names_and_taxonomy" } ] }, { "name": "CG11456-PC", "type": "synonym", "evidence": [ { "id": "NP_001262130", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262130" } ] }, { "name": "uncharacterized protein, isoform C", "type": "synonym", "evidence": [ { "id": "NP_001262130", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262130" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VPA2", "url": "https://www.uniprot.org/uniprotkb/Q9VPA2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG11456", "url": "https://www.uniprot.org/uniprotkb/Q9VPA2", "locus": { "chromosome": "3L", "start_pos": 20844340, "end_pos": 20841987, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0037031", "url": "https://www.ensemblgenomes.org/id/FBgn0037031" } ] } } ], "crossref": [ { "id": "FB:FBgn0037031", "url": "https://alliancegenome.org/gene/FB:FBgn0037031", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0037031", "url": "https://bgee.org/?page=gene&gene_id=FBgn0037031", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0037031", "url": "https://flybase.org/reports/FBgn0037031", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "40309", "url": "https://www.ncbi.nlm.nih.gov/gene/40309", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VPA2", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VPA2*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GHMVYFH", "url": "https://omabrowser.org/oma/group/GHMVYFH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VPA2", "url": "https://www.orthodb.org/?gene=Q9VPA2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24408", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24408", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24408:SF67", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24408:SF67", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13894", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13894", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001262130", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262130", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VPA2", "url": "https://www.uniprot.org/uniprotkb/Q9VPA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VPA2-1", "url": "https://www.uniprot.org/uniprotkb/Q9VPA2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MENSARIVYVCSLCLRQYDLQEDLRGHLVYFHGYEPISTPSVKNKTAKTSTKEQTAAGSNSQDKQTVVERSENSEPPASELQPMPFKDFRLVLRANMLEPCSFGKECPFKFQDATKMELHCSCHKGGSFSCCECGMELPNWRRCSAHLWKAHQVDVDLLVCPVFECNYKSPISALVWRHMQVHKKWRPRVLRSLAAVQRRRKLKEQSAEMAAQPAALPPSSKKNKYYAEKTCEICNRKFVNGKTLSKHVKTVHNKIKPFICNVCGKKTARKASLIIHMRQHTGEKPLQCGECKFSTRDPSVLHKHRQRHDSQDTRSSLKCSQCDYFCIQANALKRHMRLNHAEAYRDLCCDICSFTSINVERLRAHKQDHRQGLITNCEDSMDARAAGFKYPRKVGDKNGEISADCFMPLESVDSLPHEPALDTGGVTIPAPPSEDTQFPTYLKD", "length": 445, "header": "tr|Q9VPA2-1|Q9VPA2_DROME Isoform 1 of C2H2-type domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG11456 PE=3 SV=2 CANONICAL=Q9VPA2-1" }, "isoforms": [ { "isoform_ac": "Q9VPA2-1", "url": "https://www.uniprot.org/uniprotkb/Q9VPA2/entry#Q9VPA2-1", "sequence": { "sequence": "MENSARIVYVCSLCLRQYDLQEDLRGHLVYFHGYEPISTPSVKNKTAKTSTKEQTAAGSNSQDKQTVVERSENSEPPASELQPMPFKDFRLVLRANMLEPCSFGKECPFKFQDATKMELHCSCHKGGSFSCCECGMELPNWRRCSAHLWKAHQVDVDLLVCPVFECNYKSPISALVWRHMQVHKKWRPRVLRSLAAVQRRRKLKEQSAEMAAQPAALPPSSKKNKYYAEKTCEICNRKFVNGKTLSKHVKTVHNKIKPFICNVCGKKTARKASLIIHMRQHTGEKPLQCGECKFSTRDPSVLHKHRQRHDSQDTRSSLKCSQCDYFCIQANALKRHMRLNHAEAYRDLCCDICSFTSINVERLRAHKQDHRQGLITNCEDSMDARAAGFKYPRKVGDKNGEISADCFMPLESVDSLPHEPALDTGGVTIPAPPSEDTQFPTYLKD", "length": 445, "header": "tr|Q9VPA2-1|Q9VPA2_DROME Isoform 1 of C2H2-type domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG11456 PE=3 SV=2 CANONICAL=Q9VPA2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VPA2", "url": "https://www.uniprot.org/uniprotkb/Q9VPA2" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VPA2", "url": "https://www.uniprot.org/uniprotkb/Q9VPA2" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPA2", "url": "https://www.uniprot.org/uniprotkb/Q9VPA2" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPA2", "url": "https://www.uniprot.org/uniprotkb/Q9VPA2" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VPA2", "url": "https://www.uniprot.org/uniprotkb/Q9VPA2" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VPA2", "url": "https://www.uniprot.org/uniprotkb/Q9VPA2" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VPA2", "url": "https://www.uniprot.org/uniprotkb/Q9VPA2" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPA2", "url": "https://www.uniprot.org/uniprotkb/Q9VPA2" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPA2", "url": "https://www.uniprot.org/uniprotkb/Q9VPA2" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VPA2", "url": "https://www.uniprot.org/uniprotkb/Q9VPA2" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VPA2", "url": "https://www.uniprot.org/uniprotkb/Q9VPA2" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "E7FDZ5-1", "protein_name": "Zinc finger and BTB domain-containing protein 48", "gene_name": "zbtb48", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEKLAEGSSHAQRVLSLLNKQRAFGHFCDAMLCTASGQVHLAHRNVLACFSQLFQEPTSKTPSIKFDLPLECPDDGLELLLNFFYTGDLQLDDSNLEKVQNAASGLSVPVFLIPCQGIKTPDLNEGDPSKPLLSEPQPDQTPNKKTRSGQRTKNKADAFKLSTASDDEPPALKSTTVTRSGRRVKGPSRLVGESQISVVTRLGVGRRKASFVEDKEQETGATEDGDHPRHEDASETTQTTEVDISVDDQNDDDDDVEDAANNDDDSDRGGSVDIIIEGTDEEYVPHDSPCSSTKTPRGKRKEKSSNKKNGEGTSKDSKKGAVQCPTCHKTFLSKYYLKVHNRRHTGEKPFKCGKCGKCYFRKENLLEHEARNCLTRTELVFSCSKCSMTFKKRQELRHHTVMHTGVMPNKCTSCPEQFMQKRDLKIHMIKVHGAPKPHACPLCPKCFLSRTELRLHEASKHRGEKLFVCEECGHRASSRNGLQMHIKAIHRNERPFVCQLCNHAFTQKANLSMHLRTHTGEKPFQCHLCGKTFRTQASLDKHHRTHTGERPFSCEFCEQRFTEKGPLLRHIASKHQEGRPHFCQICNKTFKAIEQLRVHVRRHKGMRKFECTLCGYKFTRQAHLRRHTQIHNRMENYSPRQRRLRNLVVEDASAAAASSGLPVQTEAQAEPADIVSIVIQQEGAAETGGEQASYPVTDGAVNAEQTGFALAEREDGVAQTEFTVADVMEQTLLVRVQEAYPIHQSDVVVEIPNTEADRKD", "length": 760 }, "evidence": [ { "id": "MGI:2140248", "url": "https://alliancegenome.org/gene/MGI:2140248#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3V777-1", "protein_name": "Zinc finger and BTB domain-containing protein 48", "gene_name": "Zbtb48", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDGSFVQHSVRVLQELNKQREKGQYCDATLDVGGLVFKAHWSVLACCSRFFQRIYGDGSGGSVVLPAGFAEIFGLLLDFFYTGHLALTSGNRDQVLLAAKELRVPEAVELCQSFQPQTSAGQAQSGPGQVSSQDVKSHLKEPTDLDEEEVFRTLSLASVDQEPRDGEQPQLSTPAQSSPAFLCGKLKQVLKPSPPADKESEDSKEPPRPFEAEGAPLQGESNEWEVVVQVEDDRDGDGDYASEPETVLTRRKSKVIRKPCAAEPALGAGSLTAEPTEGRKGAAVPVECPTCHKKFLSKYYLKVHNRKHTGEKPFECPKCGKCYFRKENLLEHEARNCMNRSEQVFTCSVCQETFRRRMELRVHMVSHTGEMPYKCSSCSQQFMQKKDLQSHMIKLHGAPKPHACPTCAKCFLSRTELQLHEAFKHRGEKLFVCEECGHRASSRNGLQMHIKAKHRNERPYVCEFCSHAFTQKANLNMHLRTHTGEKPFQCHLCGKTFRTQASLDKHNRTHTGERPFSCEFCEQRFTEKGPLLRHVASRHQEGRPHFCQICGKTFKAVEQLRVHVRRHKGVRKFECTECGYKFTRQAHLRRHMEIHDRVENYNPRQRKLRNLIIDDEKMVVVALQPPADLEVGSAEVIVESLTQGGLASQLPSQRLCSEESFASSGVLEPSLIITAAVPEDCDT", "length": 683 }, "evidence": [ { "id": "MGI:2140248", "url": "https://alliancegenome.org/gene/MGI:2140248#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P10074-1", "protein_name": "Zinc finger and BTB domain-containing protein 48", "gene_name": "ZBTB48", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDGSFVQHSVRVLQELNKQREKGQYCDATLDVGGLVFKAHWSVLACCSHFFQSLYGDGSGGSVVLPAGFAEIFGLLLDFFYTGHLALTSGNRDQVLLAARELRVPEAVELCQSFKPKTSVGQAAGGQSGLGPPASQNVNSHVKEPAGLEEEEVSRTLGLVPRDQEPRGSHSPQRPQLHSPAQSEGPSSLCGKLKQALKPCPLEDKKPEDCKVPPRPLEAEGAQLQGGSNEWEVVVQVEDDGDGDYMSEPEAVLTRRKSNVIRKPCAAEPALSAGSLAAEPAENRKGTAVPVECPTCHKKFLSKYYLKVHNRKHTGEKPFECPKCGKCYFRKENLLEHEARNCMNRSEQVFTCSVCQETFRRRMELRVHMVSHTGEMPYKCSSCSQQFMQKKDLQSHMIKLHGAPKPHACPTCAKCFLSRTELQLHEAFKHRGEKLFVCEECGHRASSRNGLQMHIKAKHRNERPHVCEFCSHAFTQKANLNMHLRTHTGEKPFQCHLCGKTFRTQASLDKHNRTHTGERPFSCEFCEQRFTEKGPLLRHVASRHQEGRPHFCQICGKTFKAVEQLRVHVRRHKGVRKFECTECGYKFTRQAHLRRHMEIHDRVENYNPRQRKLRNLIIEDEKMVVVALQPPAELEVGSAEVIVESLAQGGLASQLPGQRLCAEESFTGPGVLEPSLIITAAVPEDCDT", "length": 688 }, "evidence": [ { "id": "MGI:2140248", "url": "https://alliancegenome.org/gene/MGI:2140248#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q1H9T6-1", "protein_name": "Zinc finger and BTB domain-containing protein 48", "gene_name": "Zbtb48", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDGSFVQHSVRVLQELNKQREKGQYCDATLDVGGLVFKAHWSVLACCSHFFQRIYGDGTGGSVVLPAGFAEIFGLLLDFFYTGHLALTSGNRDQVLLAAKELRVPEAVELCQSFQPQTSVGQAQSGLGQPASQDVKSHLKEPTDLDEEEVFRTLSLASVDQEPRDTEQPQLGTPAQSTTAFLCGKLTQALKPSPSEDKESEDCKEPPRPFEAGGAPLQGESNEWEVVVQVEDDRDGDYVSEPETVLTRRKSKVIRKPCAAEPALGAGSLTAEPTDSRKGAAVPVECPTCHKKFLSKYYLKVHNRKHTGEKPFECPKCGKCYFRKENLLEHEARNCMNRSEQVFTCSVCQETFRRRMELRLHMVSHTGEMPYKCSSCSQQFMQKKDLQSHMIKLHGAPKPHACPTCAKCFLSRTELQLHEAFKHRGEKLFVCEECGHRASSRNGLQMHIKAKHRNERPYVCEFCSHAFTQKANLNMHLRTHTGEKPFQCHLCGKTFRTQASLDKHNRTHTGERPFSCEFCEQRFTEKGPLLRHVASRHQEGRPHFCQICGKTFKAVEQLRVHVRRHKGVRKFECTECGYKFTRQAHLRRHMEIHDRVENYNPRQRKLRNLIIEDEKMVVVALQPPADLEVGSAEVIVESLTQGGLASQLPSQRLCSEESFASPGVLEPSLIITAAVPEDCDT", "length": 681 }, "evidence": [ { "id": "MGI:2140248", "url": "https://alliancegenome.org/gene/MGI:2140248#orthology", "database": "AGR" }, { "id": "FB:FBgn0037031", "url": "https://alliancegenome.org/gene/FB:FBgn0037031#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VPA2", "url": "https://www.uniprot.org/uniprotkb/Q9VPA2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q9VPA2", "url": "https://www.uniprot.org/uniprotkb/Q9VPA2" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q9VPA2", "url": "https://www.uniprot.org/uniprotkb/Q9VPA2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9VPA2", "url": "https://www.uniprot.org/uniprotkb/Q9VPA2" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q9VPA2", "url": "https://www.uniprot.org/uniprotkb/Q9VPA2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q9VPA2", "url": "https://www.uniprot.org/uniprotkb/Q9VPA2" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "Q9VPA2", "url": "https://www.uniprot.org/uniprotkb/Q9VPA2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 44, "end_pos": 46, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VPA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPA2" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 230, "end_pos": 258, "start_aa": "Lys", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 44, "end_pos": 46 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VPB7-1", "uniprot_ac": "Q9VPB7", "uniprot_id": "Q9VPB7_DROME", "mass": { "chemical_mass": 100290.0, "monoisotopic_mass": 100290.0 }, "refseq": { "ac": "NP_649254", "name": "phosphorylated CTD-interacting factor 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649254" }, "gene_names": [ { "name": "Pcif1", "type": "recommended", "evidence": [ { "id": "Q9VPB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPB7" } ] }, { "name": "CG11399", "type": "synonym", "evidence": [ { "id": "NP_649254", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649254" }, { "id": "Q9VPB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPB7" } ] }, { "name": "Dmel\\CG11399", "type": "synonym", "evidence": [ { "id": "NP_649254", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649254" }, { "id": "Q9VPB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPB7" } ] }, { "name": "Dmel_CG11399", "type": "synonym", "evidence": [ { "id": "Q9VPB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPB7" } ] }, { "name": "Pcif1", "type": "synonym", "evidence": [ { "id": "NP_649254", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649254" } ] }, { "name": "dPcif1", "type": "synonym", "evidence": [ { "id": "NP_649254", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649254" }, { "id": "Q9VPB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPB7" } ] } ], "protein_names": [ { "name": "CG11399-PB", "type": "synonym", "evidence": [ { "id": "NP_649254", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649254" } ] }, { "name": "Pcif1-PB", "type": "synonym", "evidence": [ { "id": "NP_649254", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649254" } ] }, { "name": "Phosphorylated CTD-interacting factor 1", "type": "synonym", "evidence": [ { "id": "Q9VPB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPB7/entry#names_and_taxonomy" } ] }, { "name": "phosphorylated C-terminal domain (CTD)-interacting factor 1", "type": "synonym", "evidence": [ { "id": "NP_649254", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649254" } ] }, { "name": "phosphorylated CTD-interacting factor 1", "type": "synonym", "evidence": [ { "id": "NP_649254", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649254" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VPB7", "url": "https://www.uniprot.org/uniprotkb/Q9VPB7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Pcif1", "url": "https://www.uniprot.org/uniprotkb/Q9VPB7", "locus": { "chromosome": "3L", "start_pos": 20780350, "end_pos": 20786197, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0037021", "url": "https://www.ensemblgenomes.org/id/FBgn0037021" } ] } } ], "crossref": [ { "id": "FB:FBgn0037021", "url": "https://alliancegenome.org/gene/FB:FBgn0037021", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0037021", "url": "https://bgee.org/?page=gene&gene_id=FBgn0037021", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00201", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00201", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0037021", "url": "https://flybase.org/reports/FBgn0037021", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "40295", "url": "https://www.ncbi.nlm.nih.gov/gene/40295", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001202", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001202", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039881", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039881", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG11399", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG11399", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ANENHRS", "url": "https://omabrowser.org/oma/group/ANENHRS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VPB7", "url": "https://www.orthodb.org/?gene=Q9VPB7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21727", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21727", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21727:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21727:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00397", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00397", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12237", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12237", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_649254", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649254", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VPB7", "url": "https://www.uniprot.org/uniprotkb/Q9VPB7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VPB7-1", "url": "https://www.uniprot.org/uniprotkb/Q9VPB7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAANNNNSIIHNLGAGTEGLLSSVIASTGTPGMGSSPVPSRASSSSASSAAQSAWDQLTASASNNMSPSPTAGAPTVTGPILPDNLGVGAGSSPVASCSSPSTPTKTHAPSPLESMGHTPQGPPTLGPGGYGEELTAELVNQGWRKFWSKRENRPYYWNKVTGESLWEMPGTRPFDPLTDPLGICHAGGPTPIIPNMHQQQQHQHHHLKRRPSDDMHIHPNQHHMGGGPPMKKFVLAGPWDLEVCTNAVIVERPPTLLPQPHPEVEALRAAFTMKLLKTYEDLCMRRENIKAPRDSFNRWLMERKVIDTGCDPLLPSSCMPEISSSMYREIMSDIPIKIVKPKFTGDARKQLSRYAEAAKQIIESRSAPAESKKVVKWNVEDTFQWLRRTVGASYEDFQDRLAHLKRQCEPHLVETVKSSVETLCVKIYHLSADHARKIRERHSQLLKEHGIPEPTPPPPPPHLKKVWCYPIQFAVPSPRMPTIEYLQDRDHMIIKYTPATINQPDAQYINLTYLQKLEQLYRHNCFDDKKFDLFIGRVWCLLKRYQTFLGNALNSSQEAELTQAALPVPVFECLHRQFGVSFECFASPFNSYFRQYCSAFADTDAYFGSRGPFLDFKPVSGSFQVNPPHCEELIEASLLHIDKLLTDTMEPLSFIVFLPEWKSISKLDDSMYKRRSMVVLGMAHEYRHGYQHMLQKSDVLIKCMQGTQVVWLQNSAGYARWGPNEIRVEALREAFRPQRDRERERAAAAAAAAGVTSSQQSPSTPPSAASTAPTTNSCTISGVNSNSSSTATTTSTSSSPSLTTTSSSMSPLSPHTPTGNPPPQFPMTISNTSSSSNLVAASPTMSVQSDCSSPSSSTMSLSPAPASGGYPDGVTSATAAAVSITATTTTSAAGAGSAFGQANSISSSASTQAVINSAV", "length": 920, "header": "tr|Q9VPB7-1|Q9VPB7_DROME Isoform 1 of Phosphorylated CTD-interacting factor 1 OS=Drosophila melanogaster OX=7227 GN=Pcif1 PE=1 SV=1 CANONICAL=Q9VPB7-1" }, "isoforms": [ { "isoform_ac": "Q9VPB7-1", "url": "https://www.uniprot.org/uniprotkb/Q9VPB7/entry#Q9VPB7-1", "sequence": { "sequence": "MAANNNNSIIHNLGAGTEGLLSSVIASTGTPGMGSSPVPSRASSSSASSAAQSAWDQLTASASNNMSPSPTAGAPTVTGPILPDNLGVGAGSSPVASCSSPSTPTKTHAPSPLESMGHTPQGPPTLGPGGYGEELTAELVNQGWRKFWSKRENRPYYWNKVTGESLWEMPGTRPFDPLTDPLGICHAGGPTPIIPNMHQQQQHQHHHLKRRPSDDMHIHPNQHHMGGGPPMKKFVLAGPWDLEVCTNAVIVERPPTLLPQPHPEVEALRAAFTMKLLKTYEDLCMRRENIKAPRDSFNRWLMERKVIDTGCDPLLPSSCMPEISSSMYREIMSDIPIKIVKPKFTGDARKQLSRYAEAAKQIIESRSAPAESKKVVKWNVEDTFQWLRRTVGASYEDFQDRLAHLKRQCEPHLVETVKSSVETLCVKIYHLSADHARKIRERHSQLLKEHGIPEPTPPPPPPHLKKVWCYPIQFAVPSPRMPTIEYLQDRDHMIIKYTPATINQPDAQYINLTYLQKLEQLYRHNCFDDKKFDLFIGRVWCLLKRYQTFLGNALNSSQEAELTQAALPVPVFECLHRQFGVSFECFASPFNSYFRQYCSAFADTDAYFGSRGPFLDFKPVSGSFQVNPPHCEELIEASLLHIDKLLTDTMEPLSFIVFLPEWKSISKLDDSMYKRRSMVVLGMAHEYRHGYQHMLQKSDVLIKCMQGTQVVWLQNSAGYARWGPNEIRVEALREAFRPQRDRERERAAAAAAAAGVTSSQQSPSTPPSAASTAPTTNSCTISGVNSNSSSTATTTSTSSSPSLTTTSSSMSPLSPHTPTGNPPPQFPMTISNTSSSSNLVAASPTMSVQSDCSSPSSSTMSLSPAPASGGYPDGVTSATAAAVSITATTTTSAAGAGSAFGQANSISSSASTQAVINSAV", "length": 920, "header": "tr|Q9VPB7-1|Q9VPB7_DROME Isoform 1 of Phosphorylated CTD-interacting factor 1 OS=Drosophila melanogaster OX=7227 GN=Pcif1 PE=1 SV=1 CANONICAL=Q9VPB7-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 191, "start_aa": "Thr", "end_pos": 191, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr191", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 30, "start_aa": "Thr", "end_pos": 30, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr30", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 456, "start_aa": "Thr", "end_pos": 456, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr456", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 71, "start_aa": "Thr", "end_pos": 71, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr71", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VPB7", "url": "https://www.uniprot.org/uniprotkb/Q9VPB7" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VPB7", "url": "https://www.uniprot.org/uniprotkb/Q9VPB7" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPB7", "url": "https://www.uniprot.org/uniprotkb/Q9VPB7" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPB7", "url": "https://www.uniprot.org/uniprotkb/Q9VPB7" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VPB7", "url": "https://www.uniprot.org/uniprotkb/Q9VPB7" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VPB7", "url": "https://www.uniprot.org/uniprotkb/Q9VPB7" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VPB7", "url": "https://www.uniprot.org/uniprotkb/Q9VPB7" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPB7", "url": "https://www.uniprot.org/uniprotkb/Q9VPB7" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPB7", "url": "https://www.uniprot.org/uniprotkb/Q9VPB7" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VPB7", "url": "https://www.uniprot.org/uniprotkb/Q9VPB7" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VPB7", "url": "https://www.uniprot.org/uniprotkb/Q9VPB7" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG11399", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG11399", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4IKJ1-1", "protein_name": "mRNA (2'-O-methyladenosine-N(6)-)-methyltransferase", "gene_name": "pcif1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTSENHTTIKADSALVMSPTGSTSQAAPFSPSTSKPIQELPDELIQAGWSKCWSKRENRPYYFNRFTNQSLWEMPVLGQHDVISDPLGLNAAPASGEANADAGLGNGQRKRHPSEDASQAGPNSFKRPKVEIPATPTTPTVPISPSTPGVKPWVNTTTDEKQGQASTPAPAPYRPSVVYWDLDIQTNAVIRERAPADHLPPHPEIELQRAQLTTKLRQHYHELCSQREGIEPPRESFNRWLLERKVVDKGLDPLLPSECDPVISPSMFREIMNDIPIRLSRIKYKEEARKLLFKYAEAAKKMIDSRNATPESRKVVKWNVEDTMNWLRRDHSASKEDYMDRLEHLRKQCGPHVASVAKDSVEGICSKIYHISAEYVRRIRQAHLTLLKECNISVDGTESAEVQDRLVYCYPVRLSIPAPPQTRVELHFENDIACLRFKGEMVKVSRGHFNKLELLYRYSCIDDPRFEKFLSRVWCLIKRYQVMFGSGVNEGSGLQGSLPVPVFEALNKQFGVTFECFASPLNCYFKQFCSAFPDIDGFFGSRGPFLSFSPASGSFEANPPFCEELMDAMVTHFEDLLGRSSEPLSFIIFVPEWRDPPTPALTRMEASRFRRHQMTVPAFEHEYRSGSQHICKREEIYYKAIHGTAVIFLQNNAGFAKWEPTTERIQELLAAYKVSGRSLPSPGPSSTNTGEKDSKPAPERTAPSQDNSSPVDKTAQDTTNT", "length": 721 }, "evidence": [ { "id": "RGD:1310800", "url": "https://alliancegenome.org/gene/RGD:1310800#orthology", "database": "AGR" }, { "id": "HGNC:16200", "url": "https://alliancegenome.org/gene/HGNC:16200#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120920-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120920-2#orthology", "database": "AGR" }, { "id": "MGI:2443858", "url": "https://alliancegenome.org/gene/MGI:2443858#orthology", "database": "AGR" }, { "id": "FB:FBgn0037021", "url": "https://alliancegenome.org/gene/FB:FBgn0037021#orthology", "database": "AGR" }, { "id": "Q9VPB7", "url": "https://omabrowser.org/oma/group/Q9VPB7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0YWB0-1", "protein_name": "mRNA (2'-O-methyladenosine-N(6)-)-methyltransferase", "gene_name": "PCIF1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MANENHGSPAEEASLMSHSPGTSNQNQPSSPKPMRLVQDLPDELVQAGWEKCWSKRENRPYYFNRFTNQSLWEMPVLGQHDVISDPLGLNAAPMPLESGMVETSVESKQRKRRFSEEVPPSGNSVKKPKSDIPGNPAAQPVPSSPSIPGSSVLKAWCVSPEDKQQAALLRPTEVYWDLDIQTNAVIKQRAPSEVLSPHPEVELLRSQLILKLRQHYRELCQQREGIDPPRESFNRWMLERKVVDKGTDPLLPSDCEPVVSPSMFREIMNDIPIRLSRIKFREEAKRLLFKYAEAAKRLIESRSASPDSRKVVKWNVEDTFSWLRRDHSASKEDYMDRLEHLRKQCGPHVSAAAKDSVEGICSKIYYISLEYVKRIREKHLAILKENNISAEVEAPEVQDRLVYCYPVRLAIPSPPLPSVEMHMENNVACVRYKGEMVKVSRNYFSKLWLLYRYSCIDDSGFEKFLPRVWCLLRRYQMMFGVGLYEGTGLQGALPVHVFEALHKLFGVSFECFASPLNCYFKQYCSAFLDTDGYFGSRGPCLDFFPISGSFEANPPFCEELMDAMVSHFEKLLESSSEPLSFIVFIPEWRDPPTPALTRMEQSKFKRHQLILSAFDHEYRSGSQHVCKKEEMYYKAVHNTAVLFLQNSAGFAKWEPTPERLQELVAAYKHSGRTLSSSSSSSSSSTSSTDKERELGREQSSSRETNAN", "length": 707 }, "evidence": [ { "id": "Q9VPB7", "url": "https://omabrowser.org/oma/group/Q9VPB7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0ABK0LF07-1", "protein_name": "mRNA (2'-O-methyladenosine-N(6)-)-methyltransferase", "gene_name": "Pcif1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MANENHGSPREEASLLSHSPGTSNQNQPCSPKPVRLVQDLPEELVHAGWEKCWSRRESRPYYFNRFTNQSLWEMPVLGQHDVLSDPLGLNATPLPQDSTLVETPPVENKPRKRQLSEEQPSGNGVKKPKIEIPVTPTSQSVPSSPSIPGTPILKIWGASTEDKQAALLRPTEVYWDLDIQTNAVIKHRGPSEVLPPHPEVELLRSQLILKLRQHYRELCQQREGIEPPRESFNRWMLERKVVDKGCDPLLPSNCEPVVSPSMFREIMNDIPIRLSRIKFREEAKRLLFKYAEAARRLIESRSASPDSRKVVKWNVEDTFSWLRKEHSASKEDYMDRLEHLRRQCGPHVSAAAKDSVEGICSKIYHISLEYVKRIREKHLAILKENNIPEEVEASELEPRLVYCYPVRLAVSAPPMPSVEMHMENSVVCIRYKGEMVKVSRSYFSKLWLLYRYSCVDDSAFERFLPRVWCLLRRYQMMFGVGLYEGTGLQGSLPVHVFEALHRLFGVSFECFASPLNCYFRQYCSAFPDTDGYFGSRGPCLDFTPLSGSFEANPPFCEELMDAMVSHFEKLLESSPEPLSFIVFIPEWREPPTPALTRMEQSRFKRHQLVLSAFEHEYRSGSQHICKKEEMHYKAVHNTAVLFLQNDPGFAKWGPTPERLQELTAAYKQSGRSHGSSSSSSSSSSEAKDRDSGREQGPSREPHPT", "length": 704 }, "evidence": [ { "id": "RGD:1310800", "url": "https://alliancegenome.org/gene/RGD:1310800#orthology", "database": "AGR" }, { "id": "HGNC:16200", "url": "https://alliancegenome.org/gene/HGNC:16200#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120920-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120920-2#orthology", "database": "AGR" }, { "id": "MGI:2443858", "url": "https://alliancegenome.org/gene/MGI:2443858#orthology", "database": "AGR" }, { "id": "FB:FBgn0037021", "url": "https://alliancegenome.org/gene/FB:FBgn0037021#orthology", "database": "AGR" }, { "id": "Q9VPB7", "url": "https://omabrowser.org/oma/group/Q9VPB7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MJ19-1", "protein_name": "mRNA (2'-O-methyladenosine-N(6)-)-methyltransferase", "gene_name": "PCIF1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MANENHGSPREEASLLSHSPGTSSQSQPCSPKPIRLVQDLPEELVHAGWEKCWSRRENRPYYFNRFTNQSLWEMPVLGQHDVISDPLGLNATPLPQDSSLVETPLAENKPRKRQLSEEQPSGNGVKKPKIEIPMTPTGPSVPSSPSIPGTPTLKIWGTSPEDKQQAALLRPTEVYWDLDIQTNAVIKHRGPSEVLPPHPEVELLRSQLILKLRQHYRELCQQREGIEPPRESFNRWMLERKVVDKGSDPLLPSNCEPVVSPSMFREIMNDIPIRLSRIKFREEAKRLLFKYAEAARRLIESRSASPDSRKVVKWNVEDTFSWLRKDHSASKEDYMDRLEHLRRQCGPHVSAAAKDSVEGICSKIYHISLEYVKRIREKHLAILKENNIPEEVEAPEVEPRLVYCYPVRLAVPAPPMPSVEMHVENSVVCVRYKGEMVKVSRNYFSKLWLLYRYSCIDDSAFERFLPRVWCLLRRYQMMFGVGLYEGTGLQGSLPVHVFEALHRLFGVSFECFASPLNCYFRQYCSAFPDTDGYFGSRGPCLDFSPLSGSFEANPPFCEELMDAMVSHFEKLLESSPEPLSFIVFIPEWREPPTPALTRMEQSRFKRHQLVLPAFEHEYRSGSQHVCKKEEMHYKAVHNTAVLFLQNEPGFAKWGPTPERLQELSAACRQSGRSHGSSGSASSEAKDRDSGRDQGPSREPHST", "length": 702 }, "evidence": [ { "id": "Q9VPB7", "url": "https://omabrowser.org/oma/group/Q9VPB7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SC59-1", "protein_name": "mRNA (2'-O-methyladenosine-N(6)-)-methyltransferase", "gene_name": "PCIF1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANENHGSPREEASLLSHSPGTSNQNQPCSPKPIRLVQDLPEELVHAGWEKCWSRRENRPYYFNRFTNQSLWEMPVLGQHDVISDPLGLNATPLPQDSSLVETPPAENKPRKRQLSEEQPSGNGVKKPKIEIPVTPTGPSVPSSPSIPGTPTLKIWGTSSEDKQQAALLRPTELYWDLDIQTNAVIKHRGPSEVLPPHPEVELLRSQLILKLRQHYRELCQQREGIEPPRESFNRWMLERKVVDKGSDPLLPSNCEPVVSPSMFREIMNDIPIRLSRIKFREEAKRLLFKYAEAARRLIESRSASPDSRKVVKWNVEDTFSWLRKDHSASKEDYMDRLEHLRRQCGPHVSAAAKDSVEGICSKIYHISLEYVKRIREKHLAILKENNIPEEVEAPEVEPRLVYCYPVRLAVSAPPMPSVEMHMENSVVCIRYKGEMVKVSRNYFSKLWLLYRYSCIDDSAFERFLPRVWCLLRRYQMMFGVGLYEGTGLQGSLPVHVFEALHRLFGVSFECFASPLNCYFRQYCSAFPDTDGYFGSRGPCLDFSPLSGSFEANPPFCEELMDAMVSHFERLLESSPEPLSFIVFIPEWREPPTPALTRMEQSRFKRHQLVLPAFEHEYRSGSQHVCKKEEMHYKAVHNTAVLFLQNDPGFAKWGPTPERLQELSAAYRQSGRSHGSGSSSSSSEAKDRDSGREQGPSREPHPT", "length": 703 }, "evidence": [ { "id": "Q9VPB7", "url": "https://omabrowser.org/oma/group/Q9VPB7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": 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"database": "UniProtKB", "id": "Q9VPB7", "url": "https://www.uniprot.org/uniprotkb/Q9VPB7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "wing disc dorsal/ventral pattern formation", "id": "GO:0048190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048190", "evidence": [ { "database": "UniProtKB", "id": "Q9VPB7", "url": "https://www.uniprot.org/uniprotkb/Q9VPB7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 511, "end_pos": 513, "annotation": "n_glycosylation_sequon" }, { "start_pos": 555, "end_pos": 557, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" }, { "start_pos": 787, "end_pos": 789, "annotation": "n_glycosylation_sequon" }, { "start_pos": 832, "end_pos": 834, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": 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"start_pos": 65, "end_pos": 67 }, { "start_pos": 6, "end_pos": 8 }, { "start_pos": 787, "end_pos": 789 }, { "start_pos": 832, "end_pos": 834 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"peroxin 16", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649252" }, "gene_names": [ { "name": "Pex16", "type": "recommended", "evidence": [ { "id": "Q9VPB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPB9" } ] }, { "name": "CG3947", "type": "synonym", "evidence": [ { "id": "NP_649252", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649252" }, { "id": "Q9VPB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPB9" } ] }, { "name": "DmelPex16", "type": "synonym", "evidence": [ { "id": "NP_649252", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649252" }, { "id": "Q9VPB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPB9" } ] }, { "name": "Dmel\\CG3947", "type": "synonym", "evidence": [ { "id": "NP_649252", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649252" }, { "id": "Q9VPB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPB9" } ] }, { "name": "Dmel_CG3947", "type": "synonym", "evidence": [ { "id": "Q9VPB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPB9" } ] }, { "name": "PEX16", "type": "synonym", "evidence": [ { "id": "NP_649252", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649252" }, { "id": "Q9VPB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPB9" } ] }, { "name": "Pex16", "type": "synonym", "evidence": [ { "id": "NP_649252", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649252" } ] }, { "name": "pex16", "type": "synonym", "evidence": [ { "id": "NP_649252", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649252" }, { "id": "Q9VPB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPB9" } ] } ], "protein_names": [ { "name": "Peroxisomal membrane protein PEX16", "type": "recommended", "evidence": [ { "id": "Q9VPB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPB9/entry#names_and_taxonomy" } ] }, { "name": "CG3947-PA", "type": "synonym", "evidence": [ { "id": "NP_649252", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649252" } ] }, { "name": "Pex16-PA", "type": "synonym", "evidence": [ { "id": "NP_649252", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649252" } ] }, { "name": "peroxin 16", "type": "synonym", "evidence": [ { "id": "NP_649252", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649252" } ] } ], "function": [], "disease": [ { "disease_id": "DOID:0080483", "recommended_name": { "id": "DOID:0080483", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080483", "name": "peroxisome biogenesis disorder 8A", "description": "A Zellweger syndrome that has_material_basis_in homozygous mutation in the PEX16 gene on chromosome 11p11." }, "synonyms": [ { "id": "DOID:0080483", 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"https://www.uniprot.org/uniprotkb/Q9VPB9", "locus": { "chromosome": "3L", "start_pos": 20776766, "end_pos": 20778264, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0037019", "url": "https://www.ensemblgenomes.org/id/FBgn0037019" } ] } } ], "crossref": [ { "id": "FB:FBgn0037019", "url": "https://alliancegenome.org/gene/FB:FBgn0037019", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0037019", "url": "https://bgee.org/?page=gene&gene_id=FBgn0037019", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0037019", "url": "https://flybase.org/reports/FBgn0037019", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "40293", "url": "https://www.ncbi.nlm.nih.gov/gene/40293", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG3947", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3947", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTWQSTY", "url": "https://omabrowser.org/oma/group/PTWQSTY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VPB9", "url": "https://www.orthodb.org/?gene=Q9VPB9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13299", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13299", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13299:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13299:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08610", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08610", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-9603798", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9603798", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_649252", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649252", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VPB9", "url": "https://www.uniprot.org/uniprotkb/Q9VPB9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VPB9-1", "url": "https://www.uniprot.org/uniprotkb/Q9VPB9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDTLKGMLKAYEAWVGKNPDVVGDFETTAKWVSYFIAGRISSSNVVSELVYTLSNMLVFYNDRIIEKARNSEENSVIHLQSKLCYRLKVTLTTLEYSEVFIEISARRLFGQSGKWLVIALIQAFKAAGRFFILKHSTSDIITSPPIAALNRRAKQRKNSGDGVASSTNDLLQSQHSITFQLKRSGRVIRKVEGAPPLQYRDFKLHIDNNEAAKTQIPRKLLQAEYLYISKPLIHLVAMGLFGRRSWKQYMVALSIDLYSIHLYRQHRDLMSKQQKLELSRRCINIMYFLVRSPFYDSFTKSRLERILDFVATSVPIAKVVAKPLKDYIPTWQSTYFYLWST", "length": 341, "header": "tr|Q9VPB9-1|Q9VPB9_DROME Isoform 1 of Peroxisomal membrane protein PEX16 OS=Drosophila melanogaster OX=7227 GN=Pex16 PE=1 SV=1 CANONICAL=Q9VPB9-1" }, "isoforms": [ { "isoform_ac": "Q9VPB9-1", "url": "https://www.uniprot.org/uniprotkb/Q9VPB9/entry#Q9VPB9-1", "sequence": { "sequence": "MDTLKGMLKAYEAWVGKNPDVVGDFETTAKWVSYFIAGRISSSNVVSELVYTLSNMLVFYNDRIIEKARNSEENSVIHLQSKLCYRLKVTLTTLEYSEVFIEISARRLFGQSGKWLVIALIQAFKAAGRFFILKHSTSDIITSPPIAALNRRAKQRKNSGDGVASSTNDLLQSQHSITFQLKRSGRVIRKVEGAPPLQYRDFKLHIDNNEAAKTQIPRKLLQAEYLYISKPLIHLVAMGLFGRRSWKQYMVALSIDLYSIHLYRQHRDLMSKQQKLELSRRCINIMYFLVRSPFYDSFTKSRLERILDFVATSVPIAKVVAKPLKDYIPTWQSTYFYLWST", "length": 341, "header": "tr|Q9VPB9-1|Q9VPB9_DROME Isoform 1 of Peroxisomal membrane protein PEX16 OS=Drosophila melanogaster OX=7227 GN=Pex16 PE=1 SV=1 CANONICAL=Q9VPB9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VPB9", "url": "https://www.uniprot.org/uniprotkb/Q9VPB9" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VPB9", "url": "https://www.uniprot.org/uniprotkb/Q9VPB9" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPB9", "url": "https://www.uniprot.org/uniprotkb/Q9VPB9" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPB9", "url": "https://www.uniprot.org/uniprotkb/Q9VPB9" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VPB9", "url": "https://www.uniprot.org/uniprotkb/Q9VPB9" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VPB9", "url": "https://www.uniprot.org/uniprotkb/Q9VPB9" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VPB9", "url": "https://www.uniprot.org/uniprotkb/Q9VPB9" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPB9", "url": "https://www.uniprot.org/uniprotkb/Q9VPB9" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPB9", "url": "https://www.uniprot.org/uniprotkb/Q9VPB9" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VPB9", "url": "https://www.uniprot.org/uniprotkb/Q9VPB9" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VPB9", "url": "https://www.uniprot.org/uniprotkb/Q9VPB9" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG3947", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3947", "resource": "KEGG Pathway" }, { "id": "R-DME-9603798", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9603798", "resource": "Reactome", "description": "Class I peroxisomal membrane protein import" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JWT6-1", "protein_name": "Peroxisomal membrane protein PEX16", "gene_name": "Pex16", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEKLRLLGLRYQEYVTRHPAATAQLETAVRGLSYLLAGRFSDSHELSELVYSASNLLVLLNDGILRKELRKKLPVSLSQQKLLTWLSVLECVEVFMEMGAAKVWGEVGRWLVIALIQLAKAVLRMFLLIWFKTGIQTSPPIVPLDRETQAQPLDGDHNLGSPEPSYVGKRSNRVVRTLQNSPSLHSRHWGAPQQREIRQKQQQEELSTPPTPLGLQETIAESLYIARPLLHLLSLGLWGQRSWAPWLLSGVVDMTSLSLLSDRKNLTRRERLELRRRTILLLYYLLRSPFYDRFSEAKILFLLQLLADHIPGIGLVARPLMDYLPSWQKIYFYSWG", "length": 336 }, "evidence": [ { "id": "RGD:1311372", "url": "https://alliancegenome.org/gene/RGD:1311372#orthology", "database": "AGR" }, { "id": "HGNC:8857", "url": "https://alliancegenome.org/gene/HGNC:8857#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050626-49", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050626-49#orthology", "database": "AGR" }, { "id": "MGI:1338829", "url": "https://alliancegenome.org/gene/MGI:1338829#orthology", "database": "AGR" }, { "id": "FB:FBgn0037019", "url": "https://alliancegenome.org/gene/FB:FBgn0037019#orthology", "database": "AGR" }, { "id": "Q9VPB9", "url": "https://omabrowser.org/oma/group/Q9VPB9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0ZNB2-1", "protein_name": "Peroxisomal membrane protein PEX16", "gene_name": "PEX16", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAAAAPSRGAVQRLRQLCQRYQEYVRRHPAATAQLEGTVRGLSYLLPGRFADAHELSELVYSASNLLVLLNDWILRKELPRGPPGSLPQQKLLTWLSVLECVEVFAEMGTARVWGEMGRWTIIVLIQLAKAILRLLLLLWYKAGIQTSPPIVPLNREQQQSLHSEDVEGSSSGKDQTFVGRRSSRVVRSLQNTPSLQSRHWGSPQQREETQSRRAEEMNQPPTPLGLQETIAESIYVTRPLLHLLSLGVWGQRSWKPWLLSAVLDISSLSLLSDLKDLNRRERAELRRRTILLLYYLLRSPFYDRYSEARILFLLRLLADYVPGLGFVTRPLMDYLPAWQKIYFYNWG", "length": 349 }, "evidence": [ { "id": "Q9VPB9", "url": "https://omabrowser.org/oma/group/Q9VPB9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3GYH9-1", "protein_name": "Peroxisomal membrane protein PEX16", "gene_name": "Pex16", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEKLRLLGLRYQEYVTRHPAATAQLETAVRGLSYLLAGRFSDSHELSELVYSASNLLVLLNDGILRKELRKKLPVSLSQQKLLTWLSVLECVEVFMEMGAAKVWGEVGRWLVIALIQLAKAVLRMFLLIWFKAGIQTSPPIVPLNRETQAQPLDGDHNPGSQEPSYVGKRSNRVVRTLQNSPSLHSRHWGAPQQREIRQKQQQEELSTPPTPLGLQETIAESLYIARPLLHLLSLGFWGQRSWTPWLLSGVVDMTSLSLLSDRKSLTRRERLELRRRTILLLYYLLRSPFYDRFSEAKILFLLQLLADHIPGVGLVARPLMDYLPSWQKIYFYSWG", "length": 336 }, "evidence": [ { "id": "Q9VPB9", "url": "https://omabrowser.org/oma/group/Q9VPB9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q2KII7-1", "protein_name": "Peroxisomal membrane protein PEX16", "gene_name": "PEX16", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEKLRLLGLRYQEYVTRHPAATAQLETAVRGLSYLLAGRFADSHELSELVYSASNLLVLLNDGILRKELRKKLPMSLSQQRLLTWLSVLECVEVFMEMGATKVWGEVGRWLVIALIQLAKAVLRMFLLIWFKAGLQTSPPIVPLDREIQAQSRDGDHSSGSQEQSYVGKRSNRVVRTLQNTPSLHSRHWGAPQQREELGVAPTPLGLQETIAESLHIARPLLHLLSLGLWGQRSWTPWLLSGVVDVTSLSLLSDRKGLTRRERLELRRRTILLLYYLLRSPFYDRFSEAKILFLLQLLADHVPGIGLVTRPLMDYLPNWQKIYFYSWG", "length": 328 }, "evidence": [ { "id": "Q9VPB9", "url": "https://omabrowser.org/oma/group/Q9VPB9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q4QRH7-1", "protein_name": "Peroxisomal membrane protein PEX16", "gene_name": "pex16", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEKLTRVFERYQEYVRTSPAAASHLESTVRALSYLIAGRFSDSHEISELVYSASNLLVLLNDGILRKNLSRTLPMSISQQKLLTWLSVLEYVEVFVEMAAAKMWGDAGRWLVIVLIQIAKAVLRCLLLFWYKSGIQTSPPIIPLDRDSQLCSQDNNEEEDDEDSSFVGQRSGRVVRPLGSAPSLQSRLWGLPRKKKVSRNQEEELHSSPTPLGLQETIAESLYIARPLLHLASLGICGKRSWKPWILSGLLEITSFSLLSDMKALNRRERAEMRRRAFLLLYYLLRSPFYDRYSETKILFLLRFLADYVPGVGLVARPLMEYLPIWQKIYFYNWG", "length": 335 }, "evidence": [ { "id": "RGD:1311372", "url": "https://alliancegenome.org/gene/RGD:1311372#orthology", "database": "AGR" }, { "id": "HGNC:8857", "url": "https://alliancegenome.org/gene/HGNC:8857#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050626-49", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050626-49#orthology", "database": "AGR" }, { "id": "MGI:1338829", "url": "https://alliancegenome.org/gene/MGI:1338829#orthology", "database": "AGR" }, { "id": "FB:FBgn0037019", "url": "https://alliancegenome.org/gene/FB:FBgn0037019#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q550G0-1", "protein_name": "Peroxisome biogenesis factor 16", "gene_name": "pex16", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIPKQPKSNILIFLLENSDHLGLLKSLITFLPGRYGDSELFSEGLYSVANILQSYLDYRSSGILLSNNIDKISNGEKVPPPYYLTTLRWITTVQSLELFFEMLATKKGEQHDDSNSNNNNSNNNIKKMIIFIIELLKAILRLKLLIKTNGDMLVHHSFYVPSKDVKTILENNRNQQKQFQNKRPAVTMSINNNNNINNNDNNNINNNNNTNDDNFNNNNNNNNNRRTLSDQIFEQQRIVNQENNLLYQQQRELQQNESTLIKLLPPPPPKDYNTKTIGEILFIFRPVIYWVSYCIFGKKSWKPWFLSLVTELLSKSFSEYGNFKQKIRLTLLEAKELNRRKKLLFFYLIRSPFYEKFIGDGLLNKFLNFLKKIHIFKTLIDILINYLNVYRTRYFYTSAS", "length": 400 }, "evidence": [ { "id": "Q9VPB9", "url": "https://omabrowser.org/oma/group/Q9VPB9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8S8S1-1", "protein_name": "Peroxisome biogenesis protein 16", "gene_name": "PEX16", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEAYKQWVWRNREYVQSFGSFANGLTWLLPEKFSASEIGPEAVTAFLGIFSTINEHIIENAPTPRGHVGSSGNDPSLSYPLLIAILKDLETVVEVAAEHFYGDKKWNYIILTEAMKAVIRLALFRNSGYKMLLQGGETPNEEKDSNQSESQNRAGNSGRNLGPHGLGNQNHHNPWNLEGRAMSALSSFGQNARTTTSSTPGWSRRIQHQQAVIEPPMIKERRRTMSELLTEKGVNGALFAIGEVLYITRPLIYVLFIRKYGVRSWIPWAISLSVDTLGMGLLANSKWWGEKSKQVHFSGPEKDELRRRKLIWALYLMRDPFFTKYTRQKLESSQKKLELIPLIGFLTEKIVELLEGAQSRYTYISGS", "length": 367 }, "evidence": [ { "id": "Q9VPB9", "url": "https://omabrowser.org/oma/group/Q9VPB9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q91XC9-1", "protein_name": "Peroxisomal membrane protein PEX16", "gene_name": "Pex16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKLRLLSLRYQEYVTRHPAATAQLETAVRGLSYLLAGRFSDSHELSELVYSASNLLVLLNDGILRKELRKKLPVSLSQQKLLTWLSVLECVEVFMEMGAAKVWGEVGRWLVIALIQLAKAVLRMLLLIWFKAGIQTSPPIVPLDRETQAQPLDGDHNPGSQEPSYVGKRSHRVVRTLQNSPSLHSRYWGAPQQREIRQKQQQEELSTPPTPLGLQETIAESLYIARPLLHLLSLGLWGQRSWTPWLLSGVVDMTSLSLLSDRKNLTRRERLELRRRTILLLYYLLRSPFYDRFSEAKILFLLQLLTDHIPGVGLVARPLMDYLPSWQKIYFYSWG", "length": 336 }, "evidence": [ { "id": "RGD:1311372", "url": "https://alliancegenome.org/gene/RGD:1311372#orthology", "database": "AGR" }, { "id": "HGNC:8857", "url": "https://alliancegenome.org/gene/HGNC:8857#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050626-49", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050626-49#orthology", "database": "AGR" }, { "id": "MGI:1338829", "url": "https://alliancegenome.org/gene/MGI:1338829#orthology", "database": "AGR" }, { "id": "FB:FBgn0037019", "url": "https://alliancegenome.org/gene/FB:FBgn0037019#orthology", "database": "AGR" }, { "id": "Q9VPB9", "url": 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} ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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"categories": [ "Protein Classification" ] }, { "id": "PTHR12126:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12126:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00008b9z", "url": "https://www.rcsb.org/structure/pdb_00008b9z", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008ba0", "url": "https://www.rcsb.org/structure/pdb_00008ba0", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008esw", "url": "https://www.rcsb.org/structure/pdb_00008esw", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008esz", "url": "https://www.rcsb.org/structure/pdb_00008esz", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8B9Z", "url": "https://www.rcsb.org/structure/8B9Z", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8BA0", "url": "https://www.rcsb.org/structure/8BA0", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ESW", "url": "https://www.rcsb.org/structure/8ESW", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ESZ", "url": "https://www.rcsb.org/structure/8ESZ", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF01370", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01370", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-611105", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-611105", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-6799198", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6799198", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001262116", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262116", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VPE2", "url": "https://www.uniprot.org/uniprotkb/Q9VPE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VPE2-1", "url": "https://www.uniprot.org/uniprotkb/Q9VPE2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAIVLTRNLQLAKHHGSGVVGVLCLRGYSAAAAPPEDGPRPLKTTNPAAMKRGTGGRSSFNGIVATVFGATGFVGRYVCNKLGKSGTQMILPYRGDDSDVIRLKVTGDLGQVLFHFYNLEDPASIRDAVKHSNVVINLVGRDFETKNFKFKDVHVNGAERIARIAREAGVERLIHLSSLNVEANPKDLYVKGGSEWLKSKYEGELRVRDAFPNATIIRPADIYGSEDRFLRYYAHIWRRQFRSMPLWHKGEKTVKQPVYVSDVAQAIINAAKDPDSAGRIYQAVGPKRYQLSELVDWFHRLMRKDQKRWGYMRYDMRWDPTFLLKAKLNSFICPGTPIGGLHPARIEREAVTDKVLTGVPTLEDLGVTLTTMEQQVPWELRPYRAALYYDAELGEFETPSPPKCIEARDELRLFA", "length": 416, "header": "tr|Q9VPE2-1|Q9VPE2_DROME Isoform 1 of NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial OS=Drosophila melanogaster OX=7227 GN=ND-39 PE=1 SV=1 CANONICAL=Q9VPE2-1" }, "isoforms": [ { "isoform_ac": "Q9VPE2-1", "url": "https://www.uniprot.org/uniprotkb/Q9VPE2/entry#Q9VPE2-1", "sequence": { "sequence": "MAAIVLTRNLQLAKHHGSGVVGVLCLRGYSAAAAPPEDGPRPLKTTNPAAMKRGTGGRSSFNGIVATVFGATGFVGRYVCNKLGKSGTQMILPYRGDDSDVIRLKVTGDLGQVLFHFYNLEDPASIRDAVKHSNVVINLVGRDFETKNFKFKDVHVNGAERIARIAREAGVERLIHLSSLNVEANPKDLYVKGGSEWLKSKYEGELRVRDAFPNATIIRPADIYGSEDRFLRYYAHIWRRQFRSMPLWHKGEKTVKQPVYVSDVAQAIINAAKDPDSAGRIYQAVGPKRYQLSELVDWFHRLMRKDQKRWGYMRYDMRWDPTFLLKAKLNSFICPGTPIGGLHPARIEREAVTDKVLTGVPTLEDLGVTLTTMEQQVPWELRPYRAALYYDAELGEFETPSPPKCIEARDELRLFA", "length": 416, "header": "tr|Q9VPE2-1|Q9VPE2_DROME Isoform 1 of NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial OS=Drosophila melanogaster OX=7227 GN=ND-39 PE=1 SV=1 CANONICAL=Q9VPE2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VPE2", "url": "https://www.uniprot.org/uniprotkb/Q9VPE2" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VPE2", "url": "https://www.uniprot.org/uniprotkb/Q9VPE2" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPE2", "url": "https://www.uniprot.org/uniprotkb/Q9VPE2" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPE2", "url": "https://www.uniprot.org/uniprotkb/Q9VPE2" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VPE2", "url": "https://www.uniprot.org/uniprotkb/Q9VPE2" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VPE2", "url": "https://www.uniprot.org/uniprotkb/Q9VPE2" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VPE2", "url": "https://www.uniprot.org/uniprotkb/Q9VPE2" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPE2", "url": "https://www.uniprot.org/uniprotkb/Q9VPE2" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPE2", "url": "https://www.uniprot.org/uniprotkb/Q9VPE2" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VPE2", "url": "https://www.uniprot.org/uniprotkb/Q9VPE2" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VPE2", "url": "https://www.uniprot.org/uniprotkb/Q9VPE2" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] }, { "title": "Cryo-EM structures of mitochondrial respiratory complex I from Drosophila melanogaster.", "journal": "Elife", "date": "2023", "authors": "Agip Ahmed-Noor A, Chung Injae, Sanchez-Martinez Alvaro, Whitworth Alexander J, Hirst Judy", "evidence": [ { "database": "UniProtKB", "id": "Q9VPE2", "url": "https://www.uniprot.org/uniprotkb/Q9VPE2" } ], "reference": [ { "type": "PubMed", "id": "36622099", "url": "https://glygen.org/publication/PubMed/36622099" } ] }, { "title": "Resting mitochondrial complex I from Drosophila melanogaster adopts a helix-locked state.", "journal": "Elife", "date": "2023", "authors": "Padavannil Abhilash, Murari Anjaneyulu, Rhooms Shauna-Kay, Owusu-Ansah Edward, Letts James A", "evidence": [ { "database": "UniProtKB", "id": "Q9VPE2", "url": "https://www.uniprot.org/uniprotkb/Q9VPE2" } ], "reference": [ { "type": "PubMed", "id": "36952377", "url": "https://glygen.org/publication/PubMed/36952377" } ] } ], "pathway": [ { "id": "dme:Dmel_CG6020", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG6020", "resource": "KEGG Pathway" }, { "id": "R-DME-611105", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-611105", "resource": "Reactome", "description": "Respiratory electron transport" }, { "id": "R-DME-6799198", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6799198", "resource": "Reactome", "description": "Complex I biogenesis" } ], "orthologs": [ { "uniprot_canonical_ac": "F6NP87-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial", "gene_name": "ndufa9a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAAVTLICRPAGVLPKLSGTCSPVLLAAAPVTVQQRKIHHAVVPRGKGGRSSISGLAATVFGATGFLGRYVVNRLGRMGSQVVIPYRCDQYDLMYLRPMGDLGQIIFMEWDPRNKESIQRAISHSNVVINLVGREWETSNYKYEDVFVSIPLQIARATREAGIKKFIHMSHLNADIRSPSKYLRNKAVGEEAVRNEFPDAIIMKPSELFGREDRFLNHFANMRWFGTAVPLIAMGKKTVKQPVHVVDVAKAIINAIQDPEANGKTYALVGPNRYLLHDLVEYLYSVAHRPFMPYPLPRPLYHLVARFFEMNPFEPWTTRDKVDRLHTSDLKYPDLPGLEDLGITPASIEQKAIETLRRHRRQRFFEAAVGEAKPSKTVNF", "length": 380 }, "evidence": [ { "id": "HGNC:7693", "url": "https://alliancegenome.org/gene/HGNC:7693#orthology", "database": "AGR" }, { "id": "MGI:1913358", "url": "https://alliancegenome.org/gene/MGI:1913358#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q16795-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial", "gene_name": "NDUFA9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAAQSRVVRVLSMSRSAITAIATSVCHGPPCRQLHHALMPHGKGGRSSVSGIVATVFGATGFLGRYVVNHLGRMGSQVIIPYRCDKYDIMHLRPMGDLGQLLFLEWDARDKDSIRRVVQHSNVVINLIGRDWETKNFDFEDVFVKIPQAIAQLSKEAGVEKFIHVSHLNANIKSSSRYLRNKAVGEKVVRDAFPEAIIVKPSDIFGREDRFLNSFASMHRFGPIPLGSLGWKTVKQPVYVVDVSKGIVNAVKDPDANGKSFAFVGPSRYLLFHLVKYIFAVAHRLFLPFPLPLFAYRWVARVFEISPFEPWITRDKVERMHITDMKLPHLPGLEDLGIQATPLELKAIEVLRRHRTYRWLSAEIEDVKPAKTVNI", "length": 377 }, "evidence": [ { "id": "RGD:1307307", "url": "https://alliancegenome.org/gene/RGD:1307307#orthology", "database": "AGR" }, { "id": "HGNC:7693", "url": "https://alliancegenome.org/gene/HGNC:7693#orthology", "database": "AGR" }, { "id": "MGI:1913358", "url": "https://alliancegenome.org/gene/MGI:1913358#orthology", "database": "AGR" }, { "id": "FB:FBgn0037001", "url": "https://alliancegenome.org/gene/FB:FBgn0037001#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5BK63-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial", "gene_name": "Ndufa9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAAVRFQVVRALPMSRPAISAAATSVFCSSSHRQLHHAVIPHGKGGRSSVSGVVATVFGATGFLGRYVVNHLGRMGSQVIIPYRCDIYDTMHLRLMGDLGQLIFLEWDARDKDSIRKAVQHSNVVINLIGREWETRNFDFEDVFVNIPRAIAQASKEAGVERFIHVSHLNASMKSSAKSLRSKAVGEKEVRTVFPDAIIIRPSDMFGREDRFLNHFANYRWFLAVPLVSLGFKTVKQPVYVADVSKGIANATKNPDAIGKTFAFTGPNRYLLFHLVKYIFGMTHRTFIPYPLPRFVYSWIGRLFGLSPFEPWTTKDKVERIHISDVMATDLPGLEDLGVQPTPLELKSIEVLRRHRTYRWLSSEIEETKPAKTVNY", "length": 377 }, "evidence": [ { "id": "RGD:1307307", "url": "https://alliancegenome.org/gene/RGD:1307307#orthology", "database": "AGR" }, { "id": "HGNC:7693", "url": "https://alliancegenome.org/gene/HGNC:7693#orthology", "database": "AGR" }, { "id": "MGI:1913358", "url": "https://alliancegenome.org/gene/MGI:1913358#orthology", "database": "AGR" }, { "id": "FB:FBgn0037001", "url": "https://alliancegenome.org/gene/FB:FBgn0037001#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9DC69-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial", "gene_name": "Ndufa9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAVRFRVVRALPMSRPAITAAATSVFCGSSHRQLHHAVIPHGKGGRSSVSGVVATVFGATGFLGRYVVNHLGRMGSQVIIPYRCDVYDIMHLRLMGDLGQLTFLEWDARDKDSIRKAVQHSNVVINLIGREWETRNFDFEDVFVNIPRAIAQASKEAGVERFIHVSHLNASMKSSSKSLRSKAVGEKEVRSVFPEAIIIRPSDIFGREDRFLNHFANYRWFLAVPLVSLGFKTVKQPVYVADVSKGIVNATKDPDAVGKTFAFTGPNRYLLFHLVKYIFGMTHRTFIPYPLPLFVYSWIGKLFGLSPFEPWTTKDKVERIHISDVMPTDLPGLEDLGVQPTPLELKSIEVLRRHRTYRWLSSEIEETKPAKTVNY", "length": 377 }, "evidence": [ { "id": "RGD:1307307", "url": "https://alliancegenome.org/gene/RGD:1307307#orthology", "database": "AGR" }, { "id": "HGNC:7693", "url": "https://alliancegenome.org/gene/HGNC:7693#orthology", "database": "AGR" }, { "id": "MGI:1913358", "url": "https://alliancegenome.org/gene/MGI:1913358#orthology", "database": "AGR" }, { "id": "FB:FBgn0037001", "url": "https://alliancegenome.org/gene/FB:FBgn0037001#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9VPE2", "url": "https://www.uniprot.org/uniprotkb/Q9VPE2" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q9VPE2", "url": "https://www.uniprot.org/uniprotkb/Q9VPE2" } ], "pmid": "" }, { "name": "respiratory chain complex I", "id": "GO:0045271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045271", "evidence": [ { "database": "UniProtKB", "id": "Q9VPE2", "url": "https://www.uniprot.org/uniprotkb/Q9VPE2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "nucleotide binding", "id": "GO:0000166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000166", "evidence": [ { "database": "UniProtKB", "id": "Q9VPE2", "url": "https://www.uniprot.org/uniprotkb/Q9VPE2" } ], "pmid": "" }, { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "Q9VPE2", "url": "https://www.uniprot.org/uniprotkb/Q9VPE2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "mitochondrial electron transport, NADH to ubiquinone", "id": "GO:0006120", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006120", "evidence": [ { "database": "UniProtKB", "id": "Q9VPE2", "url": "https://www.uniprot.org/uniprotkb/Q9VPE2" } ], "pmid": "" }, { "name": "ubiquinone biosynthetic process", "id": "GO:0006744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006744", "evidence": [ { "database": 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"common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Tdh", "url": "https://www.uniprot.org/uniprotkb/Q9VPE8", "locus": { "chromosome": "3L", "start_pos": 20469592, "end_pos": 20466944, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0036997", "url": "https://www.ensemblgenomes.org/id/FBgn0036997" } ] } } ], "crossref": [ { "id": "FB:FBgn0036997", "url": "https://alliancegenome.org/gene/FB:FBgn0036997", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0036997", "url": "https://bgee.org/?page=gene&gene_id=FBgn0036997", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05272", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05272", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0036997", "url": "https://flybase.org/reports/FBgn0036997", "database": "FlyBase", "categories": [ 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"Protein Classification" ] }, { "id": "Q9VPE8", "url": "https://www.orthodb.org/?gene=Q9VPE8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR42687", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42687", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR42687:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42687:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01370", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01370", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_649230", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649230", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13161", "url": "https://www.rhea-db.org/rhea/13161", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q9VPE8", "url": "https://www.uniprot.org/uniprotkb/Q9VPE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VPE8-1", "url": "https://www.uniprot.org/uniprotkb/Q9VPE8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFRKCLASLALAPVASPIPLPRITPIASQLVQRRAFHQVPRESRPPKILITGGLGQLGIECAKLLRTQYGSQNVILSDIIKPSQSVLENGPYIFADILDFKGLQKIVVDHRIDWLIHFSALLSAVGEQNVPLAVRVNIEGVHNVIELAKQYKLRIFVPSTIGAFGPDSPRNPTPNVTIQRPRTIYGVSKVHAELIGEYYYHKFGLDFRCLRFPGVISSDPPGGGTTDYAVAVFHEALRNGKYTCYLRPDTRLPMMYIEDCLRALLEFMRAPNEQLKRRVYNVTAMSFTPEELFAQLGKHVPNLHVTYKPDSRQLIADAWPQVFDDSDARRDWHWQHKYDLSNLVDFMIKDVQDNYINVQPEQQTLQI", "length": 367, "header": "tr|Q9VPE8-1|Q9VPE8_DROME Isoform 1 of L-threonine 3-dehydrogenase, mitochondrial OS=Drosophila melanogaster OX=7227 GN=Tdh PE=3 SV=1 CANONICAL=Q9VPE8-1" }, "isoforms": [ { "isoform_ac": "Q9VPE8-1", "url": "https://www.uniprot.org/uniprotkb/Q9VPE8/entry#Q9VPE8-1", "sequence": { "sequence": "MFRKCLASLALAPVASPIPLPRITPIASQLVQRRAFHQVPRESRPPKILITGGLGQLGIECAKLLRTQYGSQNVILSDIIKPSQSVLENGPYIFADILDFKGLQKIVVDHRIDWLIHFSALLSAVGEQNVPLAVRVNIEGVHNVIELAKQYKLRIFVPSTIGAFGPDSPRNPTPNVTIQRPRTIYGVSKVHAELIGEYYYHKFGLDFRCLRFPGVISSDPPGGGTTDYAVAVFHEALRNGKYTCYLRPDTRLPMMYIEDCLRALLEFMRAPNEQLKRRVYNVTAMSFTPEELFAQLGKHVPNLHVTYKPDSRQLIADAWPQVFDDSDARRDWHWQHKYDLSNLVDFMIKDVQDNYINVQPEQQTLQI", "length": 367, "header": "tr|Q9VPE8-1|Q9VPE8_DROME Isoform 1 of L-threonine 3-dehydrogenase, mitochondrial OS=Drosophila melanogaster OX=7227 GN=Tdh PE=3 SV=1 CANONICAL=Q9VPE8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VPE8", "url": "https://www.uniprot.org/uniprotkb/Q9VPE8" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VPE8", "url": "https://www.uniprot.org/uniprotkb/Q9VPE8" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPE8", "url": "https://www.uniprot.org/uniprotkb/Q9VPE8" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPE8", "url": "https://www.uniprot.org/uniprotkb/Q9VPE8" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VPE8", "url": "https://www.uniprot.org/uniprotkb/Q9VPE8" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VPE8", "url": "https://www.uniprot.org/uniprotkb/Q9VPE8" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VPE8", "url": "https://www.uniprot.org/uniprotkb/Q9VPE8" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi 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"id": "NP_649229", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649229" } ] }, { "name": "magro", "type": "synonym", "evidence": [ { "id": "NP_649229", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649229" } ] } ], "function": [], "disease": [ { "disease_id": "DOID:0080217", "recommended_name": { "id": "DOID:0080217", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080217", "name": "lysosomal acid lipase deficiency", "description": "A lipid storage disease characterized by dyslipidemia and accumulation of cholesteryl esters and triglycerides within various organs that has_material_basis_in homozygous or compound heterozygous mutation in the LIPA gene on chromosome 10q23.31." }, "synonyms": [ { "id": "DOID:0080217", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080217", "name": "LAL deficiency", "description": "" }, { "id": "DOID:0080217", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080217", "name": "LAL-D", "description": "" }, { "id": "MONDO:0019149", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019149", "name": "cholesteryl ester storage disease", "description": "A form of lysosomal acid lipase deficiency characterized by progressive cholesterol esters and triglyceride accumulation in tissues and organs typically presenting with hepatosplenomegaly, liver dysfunction and/or dyslipidemia." }, { "id": "MONDO:0019149", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019149", "name": "LAL deficiency, partial", "description": "" }, { "id": "MONDO:0019149", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019149", "name": "LIPA deficiency, partial", "description": "" }, { "id": "MONDO:0019149", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019149", "name": "cholesterol ester hydrolase deficiency, partial", "description": "" }, { "id": "MONDO:0019149", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019149", "name": "cholesterol ester storage disease", "description": "" }, { "id": "MONDO:0019149", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019149", "name": "lysosomal acid lipase deficiency, partial", "description": "" }, { "id": "MONDO:0019149", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019149", "name": "CESD", "description": "" }, { "id": "MIM:278000", "resource": "MIM", "url": "https://www.omim.org/entry/278000", "name": "Cholesteryl ester storage disease", "description": "Cholesteryl ester storage disease" } ], "unlinked_id_list": [], "evidence": [ { "id": "0080217", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080217" } ] }, { "disease_id": "DOID:14497", "recommended_name": { "id": "DOID:14497", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14497", "name": "Wolman disease", "description": "A lysosomal acid lipase deficiency characterized by infantile onset of rapidly progressive accumulation of cholesteryl esters and triglycerides throughout the body, resulting in hepatosplenomegaly, severe malnutrition, jaundice, vomiting, diarrhea, steatorrhea. Death usually occurs within the first year of life." }, "synonyms": [ { "id": "DOID:14497", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14497", "name": "Acid esterase deficiency", "description": "" }, { "id": "DOID:14497", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14497", "name": "Acid lipase deficiency", "description": "" }, { "id": "DOID:14497", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14497", "name": "Wolman xanthomatosis", "description": "" }, { "id": "DOID:14497", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14497", "name": "Wolman's disease", "description": "" }, { "id": "DOID:14497", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14497", "name": "Wolman's or triglyceride storage type III disease", "description": "" }, { "id": "DOID:14497", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14497", "name": "Xanthomatosis, familial", "description": "" }, { "id": "DOID:14497", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14497", "name": "acute infantile lysosomal acid lipase deficiency", "description": "" }, { "id": "DOID:14497", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14497", "name": "complete LAL deficiency", "description": "" }, { "id": "DOID:14497", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14497", "name": "complete LIPA deficiency", "description": "" }, { "id": "DOID:14497", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14497", "name": "complete cholesterol ester hydrolase deficiency", "description": "" }, { "id": "DOID:14497", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14497", "name": "complete lysosomal acid lipase deficiency", "description": "" }, { "id": "MONDO:0019148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019148", "name": "Wolman disease", "description": "Wolman disease represents the most severe manifestation of lysosomal acid lipase deficiency. Milder phenotypes as a whole are referred to as cholesterol ester storage disease. The acid lipase enzyme plays an essential role in lysosomal hydrolysis of both esterified cholesterol and triglycerides of lipoproteic origin. In Wolman disease, the rarest form of acid lipase deficiency, these lipids accumulate in most tissues." }, { "id": "MONDO:0019148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019148", "name": "lysosomal acid lipase deficiency", "description": "" }, { "id": "MONDO:0019148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019148", "name": "Wolman disease with hypolipoproteinemia and acanthocytosis", "description": "" }, { "id": "MONDO:0019148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019148", "name": "Wolman's disease", "description": "" }, { "id": "MONDO:0019148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019148", "name": "familial xanthomatosis", "description": "" }, { "id": "MONDO:0019148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019148", "name": "liposomal acid lipase deficiency, Wolman type", "description": "" }, { "id": "MIM:620151", "resource": "MIM", "url": "https://www.omim.org/entry/620151", "name": "Wolman disease", "description": "Wolman disease" } ], "unlinked_id_list": [], "evidence": [ { "id": "14497", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14497" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VPE9", "url": "https://www.uniprot.org/uniprotkb/Q9VPE9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "mag", "url": "https://www.uniprot.org/uniprotkb/Q9VPE9", "locus": { "chromosome": "3L", "start_pos": 20462274, "end_pos": 20460683, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0036996", "url": "https://www.ensemblgenomes.org/id/FBgn0036996" } ] } } ], "crossref": [ { "id": "FB:FBgn0036996", "url": "https://alliancegenome.org/gene/FB:FBgn0036996", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0036996", "url": "https://bgee.org/?page=gene&gene_id=FBgn0036996", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0036996", "url": "https://flybase.org/reports/FBgn0036996", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "40267", "url": "https://www.ncbi.nlm.nih.gov/gene/40267", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006693", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006693", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG5932", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG5932", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QYDWGTK", "url": "https://omabrowser.org/oma/group/QYDWGTK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VPE9", "url": "https://www.orthodb.org/?gene=Q9VPE9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11005", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11005", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04083", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04083", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-192456", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-192456", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-6809371", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6809371", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_649229", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649229", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VPE9", "url": "https://www.uniprot.org/uniprotkb/Q9VPE9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VPE9-1", "url": "https://www.uniprot.org/uniprotkb/Q9VPE9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNPIFCALLFSLVAGLVLAEKSDYCLSEIVKSDERIRSHGYPTETHEVTTQDGYVLTLFRIPYSHKLKNQNEKRPPILLQHGLFSNSDCWLSSGPDNSLAYLLADAGYDVWLGNARGNIYSRNNIIISLNSHKFWHFDWHEIGTIDIPAMIDYILADTGFDQIHYAGHSQGTTVYLVMLSERPEYNALIKSGHLLAPCAFFEHGTSFIFNALGPLVGTPGGIWNQLLVDTELIPNNNLVNRLVDNSCHLSNTICNNAFIMFANGGYVNANASSMSVLIETHPAGSSSNQGIHYLQLWKSLKFRQYDWGTKKNNELYGQDLPPDYDLSKIVAPTHLYSSTNDALCGPEDVNTLVENFPHLTEDYRVPVQSFNHLDFIIAKNMKELVNDPIIERINSYEGR", "length": 399, "header": "tr|Q9VPE9-1|Q9VPE9_DROME Isoform 1 of Lipase OS=Drosophila melanogaster OX=7227 GN=mag PE=3 SV=1 CANONICAL=Q9VPE9-1" }, "isoforms": [ { "isoform_ac": "Q9VPE9-1", "url": "https://www.uniprot.org/uniprotkb/Q9VPE9/entry#Q9VPE9-1", "sequence": { "sequence": "MNPIFCALLFSLVAGLVLAEKSDYCLSEIVKSDERIRSHGYPTETHEVTTQDGYVLTLFRIPYSHKLKNQNEKRPPILLQHGLFSNSDCWLSSGPDNSLAYLLADAGYDVWLGNARGNIYSRNNIIISLNSHKFWHFDWHEIGTIDIPAMIDYILADTGFDQIHYAGHSQGTTVYLVMLSERPEYNALIKSGHLLAPCAFFEHGTSFIFNALGPLVGTPGGIWNQLLVDTELIPNNNLVNRLVDNSCHLSNTICNNAFIMFANGGYVNANASSMSVLIETHPAGSSSNQGIHYLQLWKSLKFRQYDWGTKKNNELYGQDLPPDYDLSKIVAPTHLYSSTNDALCGPEDVNTLVENFPHLTEDYRVPVQSFNHLDFIIAKNMKELVNDPIIERINSYEGR", "length": 399, "header": "tr|Q9VPE9-1|Q9VPE9_DROME Isoform 1 of Lipase OS=Drosophila melanogaster OX=7227 GN=mag PE=3 SV=1 CANONICAL=Q9VPE9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VPE9", "url": "https://www.uniprot.org/uniprotkb/Q9VPE9" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VPE9", "url": "https://www.uniprot.org/uniprotkb/Q9VPE9" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPE9", "url": "https://www.uniprot.org/uniprotkb/Q9VPE9" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPE9", "url": "https://www.uniprot.org/uniprotkb/Q9VPE9" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VPE9", "url": "https://www.uniprot.org/uniprotkb/Q9VPE9" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VPE9", "url": "https://www.uniprot.org/uniprotkb/Q9VPE9" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VPE9", "url": "https://www.uniprot.org/uniprotkb/Q9VPE9" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPE9", "url": "https://www.uniprot.org/uniprotkb/Q9VPE9" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPE9", "url": "https://www.uniprot.org/uniprotkb/Q9VPE9" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VPE9", "url": "https://www.uniprot.org/uniprotkb/Q9VPE9" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VPE9", "url": "https://www.uniprot.org/uniprotkb/Q9VPE9" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG5932", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG5932", "resource": "KEGG Pathway" }, { "id": "R-DME-192456", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-192456", "resource": "Reactome", "description": "Digestion of dietary lipid" }, { "id": "R-DME-6809371", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6809371", "resource": "Reactome", "description": "Formation of the cornified envelope" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K430-1", "protein_name": "Lipase", "gene_name": "Lipn", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPVMWLFLTTACLIRGTLSAGGFFENTVNPEVWMNASEIITYNGYPSEEYDVTTADGYILAINRIPHGRGQTGHAGPRPVVYMQHALFADNAYWLENFPNGSLGFLLADAGYDVWMGNSRGNTWSRRHKTLSVNEEKFWAFSFDEMAKYDLPGIIDFIVNKTGQEKLYFIGHSLGTTIGFIAFSTMPELAQRIKMNFALGPVISFKYPTSIFTSFFLLPRSMIKLMFGTKGFFLEDKNAKMSYVTVCNKKLLRPMCSEFMSLWAGFNKKNMNMSRLDVYMSHAPTGSSIQNILHIKQLYQSDEFRAYDWGSEAENMNHYNQSRPPLYDLTAMKVPTAIWAGGHDVLVTPQDVARILPQITNLRYFKQFPEWNHFDFVWGLDAPQRLYSKIIGLMKEYR", "length": 398 }, "evidence": [ { "id": "MGI:1917416", "url": "https://alliancegenome.org/gene/MGI:1917416#orthology", "database": "AGR" }, { "id": "FB:FBgn0036996", "url": "https://alliancegenome.org/gene/FB:FBgn0036996#orthology", "database": "AGR" }, { "id": "RGD:1560354", "url": "https://alliancegenome.org/gene/RGD:1560354#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A494BBH0-1", "protein_name": "Lipase", "gene_name": "Gm8978", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLWLLRTMCLIHVLGKIFCLIGQNKNPESNMNVSEIIKHWEYPSEEYEVVTDDGYILPINRIPHGKNNANSTAPKMVVFCLHGLFSTAGIWVSNPPDNSLAFILADAGYDVWLGNNRGSTRAKKHVTLNTDSKEFWAFSYDEMIKYDLPAIIKFILEKTGQKQIYYTGHSQGTLIALGAFATNQELAEKIKLSILIAPVHTVKYVKGAGRLPAYFTPTAFKIVFGEKEFFPTKVFSRLSQHVCDIKLVDAGCATVLGSLTGYSPEQFNTSRIDVYITHSLGESSIQILIHYGQAIRSGVFQAYDWGSPSLNMQHYNQTTPPVYNVEDMKVPTAMFSGLKDFLSNPEDVANLVPKISNLTYHKIISDFSHLDFIMGLNARKEVSEEILTILRKYDGDIQI", "length": 399 }, "evidence": [ { "id": "MGI:3647649", "url": "https://alliancegenome.org/gene/MGI:3647649#orthology", "database": "AGR" }, { "id": "FB:FBgn0036996", "url": "https://alliancegenome.org/gene/FB:FBgn0036996#orthology", "database": "AGR" }, { "id": "RGD:1565682", "url": "https://alliancegenome.org/gene/RGD:1565682#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YY49-1", "protein_name": "Lipase", "gene_name": "Lipo2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLWLLRTMCLIQVLGKIFCLFGPKKNPEAHMNVSEIIKHWDYPSEEYEVVTDDGYILPINRIPHGKNNAKSPAPKMVVFCQHGLLATPGAWVSNPPVNSLAFILADAGYDVWMGSSRGSTWAKKHVTLNPDSKEFWDFSFDQMIKYDLPATINFILDKTGQKQIYYIGHSQGTLLAIGAFATNQKLAEKIKLNILLAPIYSVQHSKGISHLASYLTPTTIKLLFGEKEFLPTVVFSEVGACVCNINFFTAICAAIMGSMGGYSPEELNKSRLDVYVKLNLAGTSVKVLIHYNQVGRSGILQAYDWGSPSLNMRHYNQTTPPVYNVEDMKVPTAMFTGLKDFLSDPEDVEILKPKIHNLTYLKTIPDFSHFDFIWGLNTREEVSEEILTILRKYDGDYI", "length": 398 }, "evidence": [ { "id": "MGI:3644466", "url": "https://alliancegenome.org/gene/MGI:3644466#orthology", "database": "AGR" }, { "id": "FB:FBgn0036996", "url": "https://alliancegenome.org/gene/FB:FBgn0036996#orthology", "database": "AGR" }, { "id": "RGD:2321667", "url": "https://alliancegenome.org/gene/RGD:2321667#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZUQ1-1", "protein_name": "Lipase", "gene_name": "Lipo1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWWLLRTMCLIHVFGKIFCLLEPNKNPESHMNVSEIIKYWNYPSLEYEVVTDDGYILPINRIPHGKNNANSSAPKMVVFCQHGLFSTPGVWVANPPDNSLAFILAEAGYDVWLGNSRGSTWAKKHVTLSPDSEEFWAFSFDQMIAYDLPATINFILNTTGQEQIYYIGHSLGTLIALGAFSTNQELAEKIKLNILIAPVRTVKYVKGFGRLLAYFSPEAFKLVFGKKEFLPTVVFSEYSKYVCNIKLVDAGCAGVLGSLTGFSEDQLNTSRIDVYITHSLAGTSTQILIHAGQAIRSGEFQAYDWGSPSLNMQHYNQTTPPLYSVENMKVPTVMFTGLKDFLADPKDVANLVPKIFNLIYHKTIPEFSHLDFIVGLNAKTEVSDEILTILGEYDSSVL", "length": 398 }, "evidence": [ { "id": "MGI:3647308", "url": "https://alliancegenome.org/gene/MGI:3647308#orthology", "database": "AGR" }, { "id": "MGI:3647649", "url": "https://alliancegenome.org/gene/MGI:3647649#orthology", "database": "AGR" }, { "id": "FB:FBgn0036996", "url": "https://alliancegenome.org/gene/FB:FBgn0036996#orthology", "database": "AGR" }, { "id": "RGD:1565682", "url": "https://alliancegenome.org/gene/RGD:1565682#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A9L7-1", "protein_name": "Lipase", "gene_name": "Lipk", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWWLLATCCMFLPGPIYGHMQESITNPEANMNISEIISYWGYPYERHDVVTEDGYILGTYRIPHGKGCSRKAVPKAVVYLQHGLIASASNWICNLPNNSLAFLLADSGYDVWLGNSRGNTWSRKHLRLSPKSPEYWAFSLDEMAKYDLPATINLILEKSGQKQLFYVGHSQGTTIAFIAFSTNPELAKKIRMFFALAPVVTVKYTQSPMKKLTTLSRKAVKILFGDKMFSTHTWLEQFIATKVCNRKLFRQLCSNFLFSLSGFDPQNLNMSRLDVYMAQSPAGTSVQNMLHWAQAVNSGQLQAFDWGNPDQNMMHFNQLTPPVYNISKMRVPTAMWSGGRDVVADEKDTKNLLPKVANLIYYKEIPHYNHMDFYLGQDAPQEVYRDLITMMEESLQN", "length": 397 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" }, { "id": "MGI:2679259", "url": "https://alliancegenome.org/gene/MGI:2679259#orthology", "database": "AGR" }, { "id": "FB:FBgn0036996", "url": "https://alliancegenome.org/gene/FB:FBgn0036996#orthology", "database": "AGR" }, { "id": "RGD:1309724", "url": "https://alliancegenome.org/gene/RGD:1309724#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AA61-1", "protein_name": "Lipase", "gene_name": "Lipm", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEILSRAWSVSHRVEIWLLILVAYLLQRNVNSGHMPTKAADPEAFMNVSEIIKHKGYPSEEYEVATEDGYILSVNRIPRGQTQLKKEGSRPVVLLQHGLLGDASNWISNLPNNSLGFILADAGFDVWMGNSRGNTWSRKHKTLSIDQDEFWAFSYDEMARFDLPAVINFILQKTGQKKIYYVGYSQGTTMGFIAFSTMPELAHKIKMYFALAPIATVKHAKSPGTKFLLLPDMMIKGLFGRQEFLYQTRFFRQLFIYLCGQMILDQICSNIILLLGGFNTNNMNMSRANVYVAHTPAGTSVQNILHWSQAVNSGELRAFDWGSETKNREKSNQPTPIRYKVRDMMVPTAMWTGGQDWLSNPDDVKTLLSEVTNLIYHKNIPEWAHVDFIWGLDAPHRVYNEIIHLMKQESSLPQGTCRVKL", "length": 422 }, "evidence": [ { "id": "MGI:1926003", "url": "https://alliancegenome.org/gene/MGI:1926003#orthology", "database": "AGR" }, { "id": "FB:FBgn0036996", "url": "https://alliancegenome.org/gene/FB:FBgn0036996#orthology", "database": "AGR" }, { "id": "RGD:1304912", "url": "https://alliancegenome.org/gene/RGD:1304912#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E2QCS7-1", "protein_name": "AB hydrolase-1 domain-containing protein", "gene_name": "Dmel\\CG17097", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTIVLNLPVCVLFLLGTLVPSNSQKWIPYANPLDEQSQLQEIGLSDQNPDNFEQSQSQSQDQIVAQILPSDASLSGGQPPNNIIQLVDEGMDRPLLLQPQNRPIETVDQSQNLIQRKLQSQSQAQALAESQAQSQAQSQAQSQAQSQAQLQAQLQAQSQAQSQAQSQAQLQSQLQSQIQSQLQSDLQSQSQLQAQLQSQLDALKQQSGLQKLAFGQLKPQVSDQPILILDSIPKPRPQFVLLPPQNGPVQQDPNLRYVIIPSPPKRKRRISPDSSTIPKVYILTPDKQIKSNTSINIDQLLKLYKYKTDKERKIAELKRQIKELKKQNLFNLVPALQLRPAIPAIELQLPVESQSEIQSQIASQQSGSLSQLQSQQNSKSSGSQSNAQSSGSQSQYQLQSDSQSSGSQSQLQSQSNPQSSGTQSQLQSQNRRLQSQLQSQNRGSQSQLQSQINPQSSGSQSQLQSQINPQSSGSQSQLQSQNRGSQSQLQSQNRGSQSQLQSEISPQSSGSQSQLQSQIDLHSDASQSQLQSQLGYDSTGSQSQLQSQLDSQLSGAQSQLQSQFNSQSSESQSQLQSQAKFRSLGAQSQSQSQLNSQSLGSQSQSQSQLNSQSSGSQSQSQSQLNSQSSGSQSQSQSQLNSQSLGSQSQSQLQIRSQLGTQTLESQSPSEVLLHIQGPSTYQDNLAESNIQTQKNRINVVTPEYKVFKTPNYLTQEDILDNTKLTTVDLIEKYGYPSETNYVTSEDGYRLCLHRIPRPGAEPVLLVHGLMASSASWVELGPKDGLAYILYRKGYDVWMLNTRGNIYSRENLNRRLKPNKYWDFSFHEIGKFDVPAAIDHILIHTHKPKIQYIGHSQGSTVFFVMCSERPNYAHKVNLMQALSPTVYLQENRSPVLKFLGMFKGKYSMLLNLLGGYEISAKTKLIQQFRQHICSGSELGSSICAIFDFVLCGFDWKSFNTTLTPIVAAHASQGASAKQIYHYAQLQGDLNFQRFDHGAVLNRVRYESSEPPAYNLSQTTSKVVLHHGEGDWLGSTSDVIRLQERLPNLVESRKVNFEGFSHFDFTLSKDVRPLLYSHVLRHLSTSLSG", "length": 1087 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "F6RR30-1", "protein_name": "Lipase", "gene_name": "Lipo4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLWLLRTMCLIHLLGKLFCSFGTKKNPEAHMNVSQIIKHWEYPSEEYEVVTDDGYILPINRIPHGKNNANSSAPKMVVFCQHGLLATPGAWVSNLPDNSLAFILADAGYDVWMGSSRGSTWAKKHVTLNTDSKEFWDFSFDQMIKYDLPATINFILDKTGQKQIYYIGHSQGTLIAIGAFATNQKLAEKIKLNILLAPIYSVQHSKGIARLTSYLTPTTIKVLFGEKEFLPTVVSSEVGAYVCDINLVTAGCAAMIGSMGGYSPEQLNMSRLDVYVKLNLAGTSVKILIHYNQIRRSGILQAYDWGSSSLNMQHYNQTTPPVYNVEDMKVPTAMFTGLKDFLSDPEDVEILKPKIHNLTYLKTIPDFSHFDFIWGLNAREEVSEEILTILRKYDGDYI", "length": 398 }, "evidence": [ { "id": "MGI:3779637", "url": "https://alliancegenome.org/gene/MGI:3779637#orthology", "database": "AGR" }, { "id": "FB:FBgn0036996", "url": "https://alliancegenome.org/gene/FB:FBgn0036996#orthology", "database": "AGR" }, { "id": "RGD:2321667", "url": "https://alliancegenome.org/gene/RGD:2321667#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6WYC8-1", "protein_name": "Lipase", "gene_name": "Lipo1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLWLLRTMCLIHVLGKIFCLIGPNKNPESNMNVSQIIKHWEYPSEEYEVVTDDGYILPINRIPHGKNNANSSAPKMVVFCLPGLFSTAGVWVSNPPDNSLAFILADAGYDVWLGNNRGSTWAKKHVTLNPDSKEFWAFSYDEMIKYDLPAIINFILEKTGQKQIYYAGHSQGTLIALGAFATNQELAEKIKLSILIAPIHTVKYVKGSGRLPAYFTPTAFKIVFGEKEFFPTKVFSRLSQHVCDIKLVDAGCATVLGSLTGYSPEQLNTSRVDVYITHSLAESSVQILIHYGQAIRSGVFQAYDWGSPSLNMQHYNQTTPPVYNVEDMKVPTAMFSGLKDFLSNPEDVANLVPKISNLTYHKIISDFSHLDFITGLNAREEVSEEILTILRKYDGDIQI", "length": 399 }, "evidence": [ { "id": "MGI:3647308", "url": "https://alliancegenome.org/gene/MGI:3647308#orthology", "database": "AGR" }, { "id": "FB:FBgn0036996", "url": "https://alliancegenome.org/gene/FB:FBgn0036996#orthology", "database": "AGR" }, { "id": "RGD:1565682", "url": "https://alliancegenome.org/gene/RGD:1565682#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0R7L1-1", "protein_name": "Lipase", "gene_name": "Lipj", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWWLLRTLCFVHVIGSIFCFLNAKPKNPEANMNVSQIISYWGYESEEHEVMTEDGYILLIFRIPHGKNENKSSHNTRRPVVYLHHGLTVSADYWILDPPSNCLAFLLADAGFEVWLGNSRGTNNARKHVRLDPDSKEFWDFSFNEQIEYDLPAIIYFILNETRQTQIYYIGHSQGVYLAYAAFATNPQLAQKIKINFALGPVVITKYLTGVFRTIAYIHPTVIKTMFGEKDIFSKSNANDILRFLCHREQIATACTSLLIVLFGYNPGNLNESRIDVYSEHIPAGTSVRSILHFSQGIRSGLFQAYDWGSESLNVLHYNQSTPPIYNIEDMKVRTAMWSGERDLLGDPKDVKNLAAKTPNLIYHKKIPHYNHMDFILGKDAVVQVYRKIIEFINRDQSE", "length": 399 }, "evidence": [ { "id": "MGI:3779637", "url": "https://alliancegenome.org/gene/MGI:3779637#orthology", "database": "AGR" }, { "id": "MGI:3644466", "url": "https://alliancegenome.org/gene/MGI:3644466#orthology", "database": "AGR" }, { "id": "FB:FBgn0036996", "url": "https://alliancegenome.org/gene/FB:FBgn0036996#orthology", "database": "AGR" }, { "id": "RGD:2321667", "url": "https://alliancegenome.org/gene/RGD:2321667#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M9PCU5-1", "protein_name": "3.1.-.-", "gene_name": "Lip4", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MCINSKNNTHIHPSGVVDCTLIALSLCLLQSGIVEGISLSLGDITLFNVNFKTPTFLGRSVAVDSNVRLENDVDPNIQEDSHLNTYSLIKKYGYPAENHTLETDDGYILTLHRIARPGATPVLLVHGLLDSSATWVMMGPNKGLGYLLYDQGYDVWMANVRGNTYSRKHVKYSTHHAKFWDFTFHEMGKHDIPATMDYILNSTGVSQLHYIGHSQGTVVFWIMASEKPEYMDKIILMQGLAPVAFLKHCRSPVVNFLAEWHLSVSLVLKLIGVHEFLPKNEFISMFNRIICDETTITKEICSNVIFLTTGFDKLQLNETMLPVIVGHSPAGASTKQMQHFGQLNRSGGFRQYDHGWLRNHWIYGTIDPPSYHLENVRAKVALYYGQNDWLAPPEDVEMLNRKLPNVVEKYLVDDKEFNHLDFIWGIDARELLWDRMLEIMRNHENSII", "length": 448 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" }, { "id": "RGD:708441", "url": "https://alliancegenome.org/gene/RGD:708441#orthology", "database": "AGR" }, { "id": "MGI:2679259", "url": "https://alliancegenome.org/gene/MGI:2679259#orthology", "database": "AGR" }, { "id": "MGI:1926003", "url": "https://alliancegenome.org/gene/MGI:1926003#orthology", "database": "AGR" }, { "id": "MGI:3779637", "url": "https://alliancegenome.org/gene/MGI:3779637#orthology", "database": "AGR" }, { "id": "MGI:3647308", "url": "https://alliancegenome.org/gene/MGI:3647308#orthology", "database": "AGR" }, { "id": "MGI:3647649", "url": "https://alliancegenome.org/gene/MGI:3647649#orthology", "database": "AGR" }, { "id": "MGI:1917416", "url": "https://alliancegenome.org/gene/MGI:1917416#orthology", "database": "AGR" }, { "id": "MGI:1914967", "url": "https://alliancegenome.org/gene/MGI:1914967#orthology", "database": "AGR" }, { "id": "MGI:3644466", "url": "https://alliancegenome.org/gene/MGI:3644466#orthology", "database": "AGR" }, { "id": "MGI:96789", "url": "https://alliancegenome.org/gene/MGI:96789#orthology", "database": "AGR" }, { "id": "RGD:1304912", "url": "https://alliancegenome.org/gene/RGD:1304912#orthology", "database": "AGR" }, { "id": "RGD:1565682", "url": "https://alliancegenome.org/gene/RGD:1565682#orthology", "database": "AGR" }, { "id": "RGD:1309724", "url": "https://alliancegenome.org/gene/RGD:1309724#orthology", "database": "AGR" }, { "id": "RGD:3008", "url": "https://alliancegenome.org/gene/RGD:3008#orthology", "database": "AGR" }, { "id": "RGD:1560354", "url": "https://alliancegenome.org/gene/RGD:1560354#orthology", "database": "AGR" }, { "id": "RGD:2321667", "url": "https://alliancegenome.org/gene/RGD:2321667#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "O46107-1", "protein_name": "Lipase 1", "gene_name": "Lip1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRCSLRMQLLLLLGLCVFISRIQGQLIGGEEDEEDEEEEEEEEESVEDETPEDRLQRKNIKQDSTLSVDKLIAKYGYESEVHHVTTEDGYILTMHRIRKQGAPPFLLQHGLVDSSAGFVVMGPNVSLAYLLADHNYDVWLGNARGNRYSRNHTTLDPDESKFWDFSWHEIGMYDLPAMIDHVLKVTGFPKLHYAGHSQGCTSFFVMCSMRPAYNDKVVSMQALAPAVYAKETEDHPYIRAISLYFNSLVGSSIREMFNGEFRFLCRMTEETERLCIEAVFGIVGRNWNEFNRKMFPVILGHYPAGVAAKQVKHFIQIIKSGRFAPYSYSSNKNMQLYRDHLPPRYNLSLVTVPTFVYYSTNDLLCHPKDVESMCDDLGNVTGKYLVPQKEFNHMDFLWAIDVRKMLYRRMLQVLGKVPEGSPEEANRSRREIRGKFIRS", "length": 439 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" }, { "id": "RGD:708441", "url": "https://alliancegenome.org/gene/RGD:708441#orthology", "database": "AGR" }, { "id": "MGI:2679259", "url": "https://alliancegenome.org/gene/MGI:2679259#orthology", "database": "AGR" }, { "id": "MGI:1926003", "url": "https://alliancegenome.org/gene/MGI:1926003#orthology", "database": "AGR" }, { "id": "MGI:3779637", "url": "https://alliancegenome.org/gene/MGI:3779637#orthology", "database": "AGR" }, { "id": "MGI:3647308", "url": "https://alliancegenome.org/gene/MGI:3647308#orthology", "database": "AGR" }, { "id": "MGI:3647649", "url": "https://alliancegenome.org/gene/MGI:3647649#orthology", "database": "AGR" }, { "id": "MGI:1917416", "url": "https://alliancegenome.org/gene/MGI:1917416#orthology", "database": "AGR" }, { "id": "MGI:1914967", "url": "https://alliancegenome.org/gene/MGI:1914967#orthology", "database": "AGR" }, { "id": "MGI:3644466", "url": "https://alliancegenome.org/gene/MGI:3644466#orthology", "database": "AGR" }, { "id": "MGI:96789", "url": "https://alliancegenome.org/gene/MGI:96789#orthology", "database": "AGR" }, { "id": "RGD:1304912", "url": "https://alliancegenome.org/gene/RGD:1304912#orthology", "database": "AGR" }, { "id": "RGD:1565682", "url": "https://alliancegenome.org/gene/RGD:1565682#orthology", "database": "AGR" }, { "id": "RGD:1309724", "url": "https://alliancegenome.org/gene/RGD:1309724#orthology", "database": "AGR" }, { "id": "RGD:3008", "url": "https://alliancegenome.org/gene/RGD:3008#orthology", "database": "AGR" }, { "id": "RGD:1560354", "url": "https://alliancegenome.org/gene/RGD:1560354#orthology", "database": "AGR" }, { "id": "RGD:2321667", "url": "https://alliancegenome.org/gene/RGD:2321667#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "O46108-1", "protein_name": "Lipase 3", "gene_name": "Lip3", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTRGALKVTILLVGLGLVLAGSRPISDCGERIEDDGYPMERHEVVTSDNYILTMHRIPYSPKTGESSNRPVAFLMHGMLSSSSDWVLMGPERSLAYMLADAGYDVWMGNARGNTYSKAHKYWPTYWQIFWNFSWNEIGMYDVPAMIDYVLAKTGQQQVQYVGHSQGTTVYLVMVSERPEYNDKIKSAHLLGPAAYMGNMKSPLTRAFAPILGQPNAIVEVCGSMEFMPSNKFKQDLGIEMCQATSPYADMCANEIFLIGGYDTEQLDYELLEHIKATSPAGASVNQNLHFCQEYNSGKFRKFDYTALRNPYEYGSYFPPDYKLKNAKAPVLLYYGANDWMCDVSDVRKLRDELPNMALDYLVPFEKWAHLDFIWGTEARKYVYDEVLKQMQSYE", "length": 394 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" }, { "id": "RGD:708441", "url": "https://alliancegenome.org/gene/RGD:708441#orthology", "database": "AGR" }, { "id": "MGI:2679259", "url": "https://alliancegenome.org/gene/MGI:2679259#orthology", "database": "AGR" }, { "id": "MGI:1926003", "url": "https://alliancegenome.org/gene/MGI:1926003#orthology", "database": "AGR" }, { "id": "MGI:3779637", "url": "https://alliancegenome.org/gene/MGI:3779637#orthology", "database": "AGR" }, { "id": "MGI:3647308", "url": "https://alliancegenome.org/gene/MGI:3647308#orthology", "database": "AGR" }, { "id": "MGI:3647649", "url": "https://alliancegenome.org/gene/MGI:3647649#orthology", "database": "AGR" }, { "id": "MGI:1917416", "url": "https://alliancegenome.org/gene/MGI:1917416#orthology", "database": "AGR" }, { "id": "MGI:1914967", "url": "https://alliancegenome.org/gene/MGI:1914967#orthology", "database": "AGR" }, { "id": "MGI:3644466", "url": "https://alliancegenome.org/gene/MGI:3644466#orthology", "database": "AGR" }, { "id": "MGI:96789", "url": "https://alliancegenome.org/gene/MGI:96789#orthology", "database": "AGR" }, { "id": "RGD:1304912", "url": "https://alliancegenome.org/gene/RGD:1304912#orthology", "database": "AGR" }, { "id": "RGD:1565682", "url": "https://alliancegenome.org/gene/RGD:1565682#orthology", "database": "AGR" }, { "id": "RGD:1309724", "url": "https://alliancegenome.org/gene/RGD:1309724#orthology", "database": "AGR" }, { "id": "RGD:3008", "url": "https://alliancegenome.org/gene/RGD:3008#orthology", "database": "AGR" }, { "id": "RGD:1560354", "url": "https://alliancegenome.org/gene/RGD:1560354#orthology", "database": "AGR" }, { "id": "RGD:2321667", "url": "https://alliancegenome.org/gene/RGD:2321667#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P04634-1", "protein_name": "Gastric triacylglycerol lipase", "gene_name": "Lipf", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWLLLITSVISTFGGAHGLFGKLGPGNPEANMNISQMITYWGYPCQEYEVVTEDGYILGVYRIPHGKNNSENIGKRPVVYLQHGLIASATNWIANLPNNSLAFMLADAGYDVWLGNSRGNTWSRKNVYYSPDSVEFWAFSFDEMAKYDLPATINFIVQKTGQEKIHYVGHSQGTTIGFIAFSTNPTLAKKIKTFYALAPVATVKYTQSPLKKISFIPTFLFKLMFGKKMFLPHTYFDDFLGTEVCSREVLDLLCSNTLFIFCGFDKKNLNVSRFDVYLGHNPAGTSVQDFLHWAQLVRSGKFQAFNWGSPSQNMLHYNQKTPPEYDVSAMTVPVAVWNGGNDILADPQDVAMLLPKLSNLLFHKEILAYNHLDFIWAMDAPQEVYNEMISMMAED", "length": 395 }, "evidence": [ { "id": "RGD:708441", "url": "https://alliancegenome.org/gene/RGD:708441#orthology", "database": "AGR" }, { "id": "MGI:1914967", "url": "https://alliancegenome.org/gene/MGI:1914967#orthology", "database": "AGR" }, { "id": "FB:FBgn0036996", "url": "https://alliancegenome.org/gene/FB:FBgn0036996#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P07098-1", "protein_name": "Gastric triacylglycerol lipase", "gene_name": "LIPF", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWLLLTMASLISVLGTTHGLFGKLHPGSPEVTMNISQMITYWGYPNEEYEVVTEDGYILEVNRIPYGKKNSGNTGQRPVVFLQHGLLASATNWISNLPNNSLAFILADAGYDVWLGNSRGNTWARRNLYYSPDSVEFWAFSFDEMAKYDLPATIDFIVKKTGQKQLHYVGHSQGTTIGFIAFSTNPSLAKRIKTFYALAPVATVKYTKSLINKLRFVPQSLFKFIFGDKIFYPHNFFDQFLATEVCSREMLNLLCSNALFIICGFDSKNFNTSRLDVYLSHNPAGTSVQNMFHWTQAVKSGKFQAYDWGSPVQNRMHYDQSQPPYYNVTAMNVPIAVWNGGKDLLADPQDVGLLLPKLPNLIYHKEIPFYNHLDFIWAMDAPQEVYNDIVSMISEDKK", "length": 398 }, "evidence": [ { "id": "RGD:708441", "url": "https://alliancegenome.org/gene/RGD:708441#orthology", "database": "AGR" }, { "id": "MGI:1914967", "url": "https://alliancegenome.org/gene/MGI:1914967#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P34163-1", "protein_name": "Sterol esterase TGL1", "gene_name": "TGL1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MYFPFLGRLSITDYIIVVLVYIESIISSVLKLIPQPMINLFEWLINFSTSSDDNTIEEKLRSAPTIHEMCAIFDISVEDHLVRTEDNYILTLHRIPPISKNRFNNKVVYLHHGLLMCSDVWCCNIERHKNLPFVLHDLGYDVWMGNNRGNKYSTAHLNKPPKSNKFWDFSIDEFAFFDIPNSIEFILDITKVDKVICIGFSQGSAQMFAAFSLSEKLNRKVSHFIAIAPAMTPKGLHNRIVDTLAKSSPGFMYLFFGRKIVLPSAVIWQRTLHPTLFNLCIDIANKILFNWKSFNILPRQKIASYAKLYSTTSVKSIVHWFQILRSQKFQMFEESDNMLNSLTRPYQIANFPTRTNIKIPILLIYGGIDSLVDIDVMKKNLPFNSVFDVKVDNYEHLDLIWGKDADTLVIAKVLRFIEFFNPGNVSVKTNQLLPSASLVEELPSTTWKTTHPTHGLSYRTHSADRSPLSVQADEADEVHNADNSRFLRRVFSTSAIDEDNENEHQDDTEDQIHKEQQRRLSAYLESSKDLRQLDANSSTTALDALNKE", "length": 548 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" }, { "id": "RGD:708441", "url": "https://alliancegenome.org/gene/RGD:708441#orthology", "database": "AGR" }, { "id": "MGI:2679259", "url": "https://alliancegenome.org/gene/MGI:2679259#orthology", "database": "AGR" }, { "id": "MGI:1926003", "url": "https://alliancegenome.org/gene/MGI:1926003#orthology", "database": "AGR" }, { "id": "MGI:3779637", "url": "https://alliancegenome.org/gene/MGI:3779637#orthology", "database": "AGR" }, { "id": "MGI:3647308", "url": "https://alliancegenome.org/gene/MGI:3647308#orthology", "database": "AGR" }, { "id": "MGI:3647649", "url": "https://alliancegenome.org/gene/MGI:3647649#orthology", "database": "AGR" }, { "id": "MGI:1917416", "url": "https://alliancegenome.org/gene/MGI:1917416#orthology", "database": "AGR" }, { "id": "MGI:1914967", "url": "https://alliancegenome.org/gene/MGI:1914967#orthology", "database": "AGR" }, { "id": "MGI:3644466", "url": "https://alliancegenome.org/gene/MGI:3644466#orthology", "database": "AGR" }, { "id": "MGI:96789", "url": "https://alliancegenome.org/gene/MGI:96789#orthology", "database": "AGR" }, { "id": "FB:FBgn0036996", "url": "https://alliancegenome.org/gene/FB:FBgn0036996#orthology", "database": "AGR" }, { "id": "RGD:1304912", "url": "https://alliancegenome.org/gene/RGD:1304912#orthology", "database": "AGR" }, { "id": "RGD:1565682", "url": "https://alliancegenome.org/gene/RGD:1565682#orthology", "database": "AGR" }, { "id": "RGD:1309724", "url": "https://alliancegenome.org/gene/RGD:1309724#orthology", "database": "AGR" }, { "id": "RGD:3008", "url": "https://alliancegenome.org/gene/RGD:3008#orthology", "database": "AGR" }, { "id": "RGD:1560354", "url": "https://alliancegenome.org/gene/RGD:1560354#orthology", "database": "AGR" }, { "id": "RGD:2321667", "url": "https://alliancegenome.org/gene/RGD:2321667#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P38571-1", "protein_name": "Lysosomal acid lipase/cholesteryl ester hydrolase", "gene_name": "LIPA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKMRFLGLVVCLVLWTLHSEGSGGKLTAVDPETNMNVSEIISYWGFPSEEYLVETEDGYILCLNRIPHGRKNHSDKGPKPVVFLQHGLLADSSNWVTNLANSSLGFILADAGFDVWMGNSRGNTWSRKHKTLSVSQDEFWAFSYDEMAKYDLPASINFILNKTGQEQVYYVGHSQGTTIGFIAFSQIPELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDHLIKDLFGDKEFLPQSAFLKWLGTHVCTHVILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAVKFQKFQAFDWGSSAKNYFHYNQSYPPTYNVKDMLVPTAVWSGGHDWLADVYDVNILLTQITNLVFHESIPEWEHLDFIWGLDAPWRLYNKIINLMRKYQ", "length": 399 }, "evidence": [ { "id": "MGI:96789", "url": "https://alliancegenome.org/gene/MGI:96789#orthology", "database": "AGR" }, { "id": "RGD:3008", "url": "https://alliancegenome.org/gene/RGD:3008#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q07804-1", "protein_name": "Sterol esterase 1", "gene_name": "YEH1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MGVSAVLKRARNLLATFIVCCFMAVVLVLALAHHFINEHRDTRSSSTQIEVDDESKRNVHHDHVLTRTNAYATPYLDLEHDKKNGIVYDHTRTVVRKKNHEVGSSSLHKNLFHKFLTKLIFRFIEKEKVTEGVTQGKFNNSSNEIANHEPVFEKIPVQCDNPLQNLILSEDLTLVADLNYYFNQYNIQIEEFRLETEDGFVIDLWHLIPKYRTTDSDKKKRPPILMLHGLLQSSGSFASNGRKSLAYFLYQSGYDIWLGNNRCGFRPEWNEAKVPTLASRWDWDLREMVKYDLTLLIDTVLAKTQFEKLTLISHSQGTTQGFMGLVNEDKFFPPGSGSKESFFTSKIANYIALAPAVYPGPLLNEKLFVKLMTKEIENPWFFGETSFFEIMMIVRNLCVGESLFSFVCYTIFNYLFDWNDTLWDTALRDRHFLFSPVHVSVKLMQWWLSPDPNKVSFKFGSHKMFPDNVKWFSDASKAPNIYLFVPKQDRLVDGERLINHFVNVESNVNYKIWYIDEYAHIDVLWAHDVIERIGKPILQNLNNYYSKKPSSAFESDCSDTEVETELEMVAEKA", "length": 573 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q07950-1", "protein_name": "Sterol esterase 2", "gene_name": "YEH2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVNKVVDEVQRLVSAIILTSFMTGLFILSLWKNYVTVHFQHKNDPRDTRSSRTKIQPNDKKKKRPARHSRPLSISSTTPLDLQRDQENNIEYDRTVTSKLSMTSNASLSENGDGNANIKMETNVNQAPYAAENPFQNIALAEDTKLVPDLKYYYKEYGIDIEEFEVETDDGFIIDLWHFKSRLNDGVEEVKREPILLLHGLLQSCGAFASSGRKSLAYFLYESGFDVWLGNNRCGLNAKWNMKKLGNDHSKKWDWDMHQMVQYDLKALINYVLDSTGYAKLSLVAHSQGTTQGFMGLVNGEKLYASDFKLVDKLENFVALAPAVYPGPLLDEKAFVRLMAKGIDSPWYFGRRSFIPLMMTMRKLMVGTKIFSFLSYIMFNYLFDWNDVLWDRVLRDRNFLFSPVHISVKLMQWWLSPLPNKLSFKKGAEKIFPDKKTWFPIAKNDDDSGNNLDNNKLHLNPKRQNSEEFPHIIMFIPKQDRLVDGERLINHFINHEANAVYKIWYIDEYSHLDVLWAHDVIDRIGKPMIENLRFPNAR", "length": 538 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q0KI77-1", "protein_name": "Lipase", "gene_name": "Dmel\\CG11598", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSYKAFVFFCLYIDLAKGLITSEIIASHNYPVEVHTVLTRDGYLLDAFRIPGSKFCQQSGPKPAVLFQHGMSASSDVFLLNGPQDSLAFMLADACFDVWLSNSRGTRYSRRHVSLDPSDEAFWRFSWHEIGTEDVAAFIDYILDTTKQRALHFLGHSQGCTTLVVLLSMRPEYNKLVKTAVLLAPAVFMRHTSTLSQTVFRSFIMAMPDKEFMYHNGVLNKLLSNVCGLFVARVFCTTFFLISNGKISKHLNTSVIPLIAATLPAGVSSRQPKHFIQLTDSGKFRPFDFGILRNLINYKSLEPPDYTLSNVRPLTPVHIFYSDDDSSTAKEDIQNFAARVPEVVMHRISTPGWHHTDFVHSMTVADVINKPVIEIFRSFERLSSPTFL", "length": 388 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" }, { "id": "RGD:708441", "url": "https://alliancegenome.org/gene/RGD:708441#orthology", "database": "AGR" }, { "id": "MGI:2679259", "url": "https://alliancegenome.org/gene/MGI:2679259#orthology", "database": "AGR" }, { "id": "MGI:1926003", "url": "https://alliancegenome.org/gene/MGI:1926003#orthology", "database": "AGR" }, { "id": "MGI:3779637", "url": "https://alliancegenome.org/gene/MGI:3779637#orthology", "database": "AGR" }, { "id": "MGI:3647308", "url": "https://alliancegenome.org/gene/MGI:3647308#orthology", "database": "AGR" }, { "id": "MGI:3647649", "url": "https://alliancegenome.org/gene/MGI:3647649#orthology", "database": "AGR" }, { "id": "MGI:1917416", "url": "https://alliancegenome.org/gene/MGI:1917416#orthology", "database": "AGR" }, { "id": "MGI:1914967", "url": "https://alliancegenome.org/gene/MGI:1914967#orthology", "database": "AGR" }, { "id": "MGI:3644466", "url": "https://alliancegenome.org/gene/MGI:3644466#orthology", "database": "AGR" }, { "id": "MGI:96789", "url": "https://alliancegenome.org/gene/MGI:96789#orthology", "database": "AGR" }, { "id": "RGD:1304912", "url": "https://alliancegenome.org/gene/RGD:1304912#orthology", "database": "AGR" }, { "id": "RGD:1565682", "url": "https://alliancegenome.org/gene/RGD:1565682#orthology", "database": "AGR" }, { "id": "RGD:1309724", "url": "https://alliancegenome.org/gene/RGD:1309724#orthology", "database": "AGR" }, { "id": "RGD:3008", "url": "https://alliancegenome.org/gene/RGD:3008#orthology", "database": "AGR" }, { "id": "RGD:1560354", "url": "https://alliancegenome.org/gene/RGD:1560354#orthology", "database": "AGR" }, { "id": "RGD:2321667", "url": "https://alliancegenome.org/gene/RGD:2321667#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q3U4B4-1", "protein_name": "Lipase member N", "gene_name": "Lipn", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPMMWLFLTTACLIPGTLSAGGFLDFENKVNPEVWMNASEIIMYNGYPSEEYDVTTADGYILAINRIPHGRAQTGQTGPRPVVYMQHALFADNAYWLENFANGSLGFILADAGYDVWMGNSRGNTWSRRHKTLSANEEKFWAFSFNEMAKYDLPGIIDFIVNKTGQEKLYFIGHSLGTTIGFVAFSTMPELAQRIKMNFALGPVISFKYPTSVFTNLFLLPKSIIKLVFGTKGVLLEDKNARMSFITFCNQKLLQPLCSEFMSLWAGFNKKNMNMSRLDVYMAHAPTGSSIQNMLHIKQLYRSDEFRAYDWGSEAENMNHYNQSYPPLYDLTAMKVPTAIWAGGHDVLVTPQDVARILPQITNLRYFKQFPDWNHFDFVWGLDAPQRLYSKIISLMKEYF", "length": 400 }, "evidence": [ { "id": "MGI:1917416", "url": "https://alliancegenome.org/gene/MGI:1917416#orthology", "database": "AGR" }, { "id": "FB:FBgn0036996", "url": "https://alliancegenome.org/gene/FB:FBgn0036996#orthology", "database": "AGR" }, { "id": "RGD:1560354", "url": "https://alliancegenome.org/gene/RGD:1560354#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q59E63-1", "protein_name": "Lipase", "gene_name": "Dmel\\CG11406", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAPEEEEPEEEVARDSLCTRSDSVCQAVQRQQLQCQVHRIETADGYRLSLHRIPAPQNRWCPQQLRPFLLMHGLLGSAGDFVSGGRGRSLALELHARCFDVWLANARGTTHSRGHRTLQTSDARFWRFSWHEIGIYDLPAIVDYVLARTNRRQLHYVGHSQGTTVLLVLLSQRPEYNARFANAALLAPVAFLQHLSSPPLRLLASDSSMATLLLNKLGLHELLPASALTQVGGQFFCTASRPTYALCTLFTSVYVGFSDYPLDRSILPRILETTPAGISRGQLQHFGQLINSGKFQQYDYRSPRLNTLRYGRTTPPSYQLANVRLQLQIFHGSRDTLSSLADVQRLVRELRNSVTQMYQVPGYNHIDFLFASSAPQVVFQRIIQQAWQLDMALAAL", "length": 396 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" }, { "id": "MGI:2679259", "url": "https://alliancegenome.org/gene/MGI:2679259#orthology", "database": "AGR" }, { "id": "MGI:1926003", "url": "https://alliancegenome.org/gene/MGI:1926003#orthology", "database": "AGR" }, { "id": "MGI:3779637", "url": "https://alliancegenome.org/gene/MGI:3779637#orthology", "database": "AGR" }, { "id": "MGI:3647308", "url": "https://alliancegenome.org/gene/MGI:3647308#orthology", "database": "AGR" }, { "id": "MGI:3647649", "url": "https://alliancegenome.org/gene/MGI:3647649#orthology", "database": "AGR" }, { "id": "MGI:1917416", "url": "https://alliancegenome.org/gene/MGI:1917416#orthology", "database": "AGR" }, { "id": "MGI:1914967", "url": "https://alliancegenome.org/gene/MGI:1914967#orthology", "database": "AGR" }, { "id": "MGI:3644466", "url": "https://alliancegenome.org/gene/MGI:3644466#orthology", "database": "AGR" }, { "id": "MGI:96789", "url": "https://alliancegenome.org/gene/MGI:96789#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q5VXI9-1", "protein_name": "Lipase member N", "gene_name": "LIPN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMWLLLTTTCLICGTLNAGGFLDLENEVNPEVWMNTSEIIIYNGYPSEEYEVTTEDGYILLVNRIPYGRTHARSTGPRPVVYMQHALFADNAYWLENYANGSLGFLLADAGYDVWMGNSRGNTWSRRHKTLSETDEKFWAFSFDEMAKYDLPGVIDFIVNKTGQEKLYFIGHSLGTTIGFVAFSTMPELAQRIKMNFALGPTISFKYPTGIFTRFFLLPNSIIKAVFGTKGFFLEDKKTKIASTKICNNKILWLICSEFMSLWAGSNKKNMNQSRMDVYMSHAPTGSSVHNILHIKQLYHSDEFRAYDWGNDADNMKHYNQSHPPIYDLTAMKVPTAIWAGGHDVLVTPQDVARILPQIKSLHYFKLLPDWNHFDFVWGLDAPQRMYSEIIALMKAYS", "length": 398 }, "evidence": [ { "id": "MGI:1917416", "url": "https://alliancegenome.org/gene/MGI:1917416#orthology", "database": "AGR" }, { "id": "RGD:1560354", "url": "https://alliancegenome.org/gene/RGD:1560354#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5VXJ0-1", "protein_name": "Lipase member K", "gene_name": "LIPK", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWQLLAAACWMLLLGSMYGYDKKGNNANPEANMNISQIISYWGYPYEEYDVTTKDGYILGIYRIPHGRGCPGRTAPKPAVYLQHGLIASASNWICNLPNNSLAFLLADSGYDVWLGNSRGNTWSRKHLKLSPKSPEYWAFSLDEMAKYDLPATINFIIEKTGQKRLYYVGHSQGTTIAFIAFSTNPELAKKIKIFFALAPVVTVKYTQSPMKKLTTLSRRVVKVLFGDKMFHPHTLFDQFIATKVCNRKLFRRICSNFLFTLSGFDPQNLNMSRLDVYLSHNPAGTSVQNMLHWAQAVNSGQLQAFDWGNSDQNMMHFHQLTPPLYNITKMEVPTAIWNGGQDIVADPKDVENLLPQIANLIYYKLIPHYNHVDFYLGEDAPQEIYQDLIILMEEYLQN", "length": 399 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" }, { "id": "MGI:2679259", "url": "https://alliancegenome.org/gene/MGI:2679259#orthology", "database": "AGR" }, { "id": "FB:FBgn0036996", "url": "https://alliancegenome.org/gene/FB:FBgn0036996#orthology", "database": "AGR" }, { "id": "RGD:1309724", "url": "https://alliancegenome.org/gene/RGD:1309724#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5VYY2-1", "protein_name": "Lipase member M", "gene_name": "LIPM", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLETLSRQWIVSHRMEMWLLILVAYMFQRNVNSVHMPTKAVDPEAFMNISEIIQHQGYPCEEYEVATEDGYILSVNRIPRGLVQPKKTGSRPVVLLQHGLVGGASNWISNLPNNSLGFILADAGFDVWMGNSRGNAWSRKHKTLSIDQDEFWAFSYDEMARFDLPAVINFILQKTGQEKIYYVGYSQGTTMGFIAFSTMPELAQKIKMYFALAPIATVKHAKSPGTKFLLLPDMMIKGLFGKKEFLYQTRFLRQLVIYLCGQVILDQICSNIMLLLGGFNTNNMNMSRASVYAAHTLAGTSVQNILHWSQAVNSGELRAFDWGSETKNLEKCNQPTPVRYRVRDMTVPTAMWTGGQDWLSNPEDVKMLLSEVTNLIYHKNIPEWAHVDFIWGLDAPHRMYNEIIHLMQQEETNLSQGRCEAVL", "length": 423 }, "evidence": [ { "id": "MGI:1926003", "url": "https://alliancegenome.org/gene/MGI:1926003#orthology", "database": "AGR" }, { "id": "RGD:1304912", "url": "https://alliancegenome.org/gene/RGD:1304912#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5W064-1", "protein_name": "Lipase member J", "gene_name": "LIPJ", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNISQIISYWGYPDEEYDIVTEDGYILGLYRIPYWRTDNNKNLAQRVVVYLQHGLLTSASSWISNLPNNSLGFILADAGYDVWMGNSRGNTWSRKHLYLETSSKEFWAFSFDEMAKYDLPASIDFTVKQTRQEEIFYVGHSQGTTIGFITFSTISKIAERIKIFFALAPVFSTKYLKSPLIRMTYKWKSIVMAFSGNKDFLPKTSFKKFIGSKLCPLQIFDKICLNILFMMFGYDPKNLNMSRLDVYFSHNPAGTSVQNMLHWSQLLNSTHLKAYDWGSPDLNLVHYNQTTSPLYNMTNMNVATAIWNGKSDLLADPEDVNILHSEITNHIYYKTISYYNHIDSLFGLDVYDQVYHEIIDIIQDNL", "length": 366 }, "evidence": [ { "id": "RGD:2321667", "url": "https://alliancegenome.org/gene/RGD:2321667#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q64194-1", "protein_name": "Lysosomal acid lipase/cholesteryl ester hydrolase", "gene_name": "Lipa", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQLLGRVICFVVGILLSGGPTGTISAVDPEANMNVTEIIMHWGYPEHSVQTGDGYILGVHRIPHGRKNQFDKGPKPVVYLQWRHGFLADSSNWVTNIDNNSLGFILADAGFDVWMGNSRGNTWSRKHKTLSVSQDEYWAFSFDEMAKYDLPASINYILNKTGQEQLYNVGHSQGCTIGFIAFSQMPELAKKVKMFFALAPVLSLNFASGPMVKLGRLPDLLLEDLFGQKQFLPQSAMVKWLSTHICTHVIMKELCANIFFLICGFNEKNLNMSRVDVYTTHCPAGTSVQNMVHWTQVVKYHKLQAFDWGSSDKNYFHYNQSYPPLYSIKDMQLPTALWSGGKDWLADTSDINILLTEIPTLVYHKNIPEWDHLDFIWGLDAPWRLYNEVVSLMKKYQ", "length": 397 }, "evidence": [ { "id": "MGI:96789", "url": "https://alliancegenome.org/gene/MGI:96789#orthology", "database": "AGR" }, { "id": "FB:FBgn0036996", "url": "https://alliancegenome.org/gene/FB:FBgn0036996#orthology", "database": "AGR" }, { "id": "RGD:3008", "url": "https://alliancegenome.org/gene/RGD:3008#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BM14-1", "protein_name": "Lipase member K", "gene_name": "Lipk", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWWLLATTCCVLLSGPIDGYKQESITNPEANMNISELISYWGYPYEKHDVITEDGYILGTYRIPHGKGCSRKTAPKAVVYLQHGLIASANNWICNLPNNSLAFLLADSGYDVWLGNSRGNTWSRNHLRLSPKSPQYWAFSWDEMAKYDLPATVNLILEKSGQKQLFYVGHSQGTTIAFIAFSTNPELAKKIRLFFALAPVATVKYTRSPMKKLTTLSRKAVKVLFGDKMFSTHTWFEQFIATKVCNRKLFHQLCSNFLFSLSGFDPQNLNMSRLDVYLSQSPAGTSVQNMLHWAQAVNSGQLQAFDWGNPDQNMMHFNQLTPPVYNISKMRVPTAMWSGGQDVVADAKDTKNLLPKIANLIYYKEIPHYNHMDFYLGQDAPQEVYGDLIRMIEESLQN", "length": 398 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" }, { "id": "MGI:2679259", "url": "https://alliancegenome.org/gene/MGI:2679259#orthology", "database": "AGR" }, { "id": "FB:FBgn0036996", "url": "https://alliancegenome.org/gene/FB:FBgn0036996#orthology", "database": "AGR" }, { "id": "RGD:1309724", "url": "https://alliancegenome.org/gene/RGD:1309724#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IMS3-1", "protein_name": "Lipase", "gene_name": "CG5990", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MYRSHIAVICAFVGIFVGTVVQSAPFSNDPAEVPNFYELFNNPDAHLSLTNGPDTIHFIEEHGYPVERHYVTTEDGYIISLFRIPYSHNIQNQQEKRPIAFIQHGLFASSDFWPSLGPDDGLPFLLSDAGYDVWLGNARGNRYSKNHTSRLTSHPDFWRFSWHEIGYFDIAAAIDYTLSTENGQDQKGIHYIGHSQGTTVMFVLLSSRPEYNDKIKTAHMLAPVAFMDHMDDVMVNTLSPYLGFNNIYSTLFCSQEFLPHNDFVLALMYSVCLPESIVYSFCSSSNETTTEEGRTNSTASALTSGVMPAGVSTDQILHYMQEHQSGHFRQFDFGTKKNMKVYGTEAPEDYPTELITAEMHLWYSDSDEMAAVEDVLRVAETLPNKVMHHMEDPLWDHMDFALNWEVRQYINDPIVAILNEYEGK", "length": 424 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" }, { "id": "RGD:708441", "url": "https://alliancegenome.org/gene/RGD:708441#orthology", "database": "AGR" }, { "id": "MGI:2679259", "url": "https://alliancegenome.org/gene/MGI:2679259#orthology", "database": "AGR" }, { "id": "MGI:1926003", "url": "https://alliancegenome.org/gene/MGI:1926003#orthology", "database": "AGR" }, { "id": "MGI:3779637", "url": "https://alliancegenome.org/gene/MGI:3779637#orthology", "database": "AGR" }, { "id": "MGI:3647308", "url": "https://alliancegenome.org/gene/MGI:3647308#orthology", "database": "AGR" }, { "id": "MGI:3647649", "url": "https://alliancegenome.org/gene/MGI:3647649#orthology", "database": "AGR" }, { "id": "MGI:1917416", "url": "https://alliancegenome.org/gene/MGI:1917416#orthology", "database": "AGR" }, { "id": "MGI:1914967", "url": "https://alliancegenome.org/gene/MGI:1914967#orthology", "database": "AGR" }, { "id": "MGI:3644466", "url": "https://alliancegenome.org/gene/MGI:3644466#orthology", "database": "AGR" }, { "id": "MGI:96789", "url": "https://alliancegenome.org/gene/MGI:96789#orthology", "database": "AGR" }, { "id": "RGD:1304912", "url": "https://alliancegenome.org/gene/RGD:1304912#orthology", "database": "AGR" }, { "id": "RGD:1565682", "url": "https://alliancegenome.org/gene/RGD:1565682#orthology", "database": "AGR" }, { "id": "RGD:1309724", "url": "https://alliancegenome.org/gene/RGD:1309724#orthology", "database": "AGR" }, { "id": "RGD:3008", "url": "https://alliancegenome.org/gene/RGD:3008#orthology", "database": "AGR" }, { "id": "RGD:1560354", "url": "https://alliancegenome.org/gene/RGD:1560354#orthology", "database": "AGR" }, { "id": "RGD:2321667", "url": "https://alliancegenome.org/gene/RGD:2321667#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8K2A6-1", "protein_name": "Lipase member M", "gene_name": "Lipm", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSEILSRVWTVSHRVEIWLLILVAYLLQRNVNSGHLPTKAADPEAFMNVSEIIKHKGYPSEEYEVATEDGYILSVNRIPRGQTRLKKEGSRPVVLLQHGLLGDASNWISNLPNNSLGFILADAGFDVWMGNSRGNTWSRKHKTLSIDQDEFWAFSYDEMARFDLPAVINFILQKTGQKKVYYVGYSQGTTMGFIAFSTMPELAHKIKMYFALAPIATVKYARSPGTKFLLLPDMMIKVLFGRQEFLYQTRFFRQLFIYLCGQMILDQICSNIILLLGGFNTNNMNMSRANVYVAHTPAGTSVQNILHWSQAVNSGELRAFDWGSETKNQEKCNQPTPIRYKVRDMMVPTAMWTGGQDWLSNPDDVKTLLSEVTNLIYHKNIPEWAHVDFIWGLDAPQRVYNEIIHLMKQEPNLPQGTCRVKL", "length": 422 }, "evidence": [ { "id": "MGI:1926003", "url": "https://alliancegenome.org/gene/MGI:1926003#orthology", "database": "AGR" }, { "id": "FB:FBgn0036996", "url": "https://alliancegenome.org/gene/FB:FBgn0036996#orthology", "database": "AGR" }, { "id": "RGD:1304912", "url": "https://alliancegenome.org/gene/RGD:1304912#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9CPP7-1", "protein_name": "Gastric triacylglycerol lipase", "gene_name": "Lipf", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWLLLVTSVLSAFGGAHGLFGKLGPKNPEANMNVSQMITYWGYPSEEYEVVTEDGYILGVYRIPYGKKNSENIGKRPVAYLQHGLIASATNWITNLPNNSLAFILADAGYDVWLGNSRGNTWSRKNVYYSPDSVEFWAFSFDEMAKYDLPATIDFIVQKTGQEKIHYVGHSQGTTIGFIAFSTNPALAKKIKRFYALAPVATVKYTESPFKKISLIPKFLLKVIFGNKMFMPHNYLDQFLGTEVCSRELLDLLCSNALFIFCGFDKKNLNVSRFDVYLGHNPAGTSTQDLFHWAQLAKSGKLQAYNWGSPLQNMLHYNQKTPPYYDVSAMTVPIAVWNGGHDILADPQDVAMLLPKLPNLLYHKEILPYNHLDFIWAMDAPQEVYNEIVTMMAED", "length": 395 }, "evidence": [ { "id": "RGD:708441", "url": "https://alliancegenome.org/gene/RGD:708441#orthology", "database": "AGR" }, { "id": "MGI:1914967", "url": "https://alliancegenome.org/gene/MGI:1914967#orthology", "database": "AGR" }, { "id": "FB:FBgn0036996", "url": "https://alliancegenome.org/gene/FB:FBgn0036996#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9V9N3-1", "protein_name": "Lipase", "gene_name": "Dmel\\CG3635", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLDNNSCAQTNILTSKEMANNSPTRGSVMLLTLVLLLLSRKIGLVDGHKVTATSISNHNYPVEEHTVITHDDYILTIYRIPSSPNRSHLNRAGRRAVVFLQHGILSASDDWIINGPEASLAYMLADAGYDVWLGNARGNTYSRQHKHIHPDTSDFWRFSWHEIGVYDLAAMLDYALAKSQSSSLHFVAHSQGTTAFFVLMSSLPLYNEKLRSVHLLAPIAYMRDHSFILSKLGGIFLGTPSFLSWVLGSMELLPITNLQKLICEHICSSSSMFNFLCSGLLDFIGGWGTRHLNQTLLPDVCATHPAGASSSQVIHYLQLYRSGDFRQYDHGPELNEIIYQQPTPPSYNVQYIKSCVDMYYSENDYMSAVGDVKYLASLLPCAQLYRIPFRDWNHYDFLWSNNVKEVINNKIIQKIRKYDEDGVGF", "length": 425 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" }, { "id": "RGD:708441", "url": "https://alliancegenome.org/gene/RGD:708441#orthology", "database": "AGR" }, { "id": "MGI:2679259", "url": "https://alliancegenome.org/gene/MGI:2679259#orthology", "database": "AGR" }, { "id": "MGI:1926003", "url": "https://alliancegenome.org/gene/MGI:1926003#orthology", "database": "AGR" }, { "id": "MGI:3779637", "url": "https://alliancegenome.org/gene/MGI:3779637#orthology", "database": "AGR" }, { "id": "MGI:3647308", "url": "https://alliancegenome.org/gene/MGI:3647308#orthology", "database": "AGR" }, { "id": "MGI:3647649", "url": "https://alliancegenome.org/gene/MGI:3647649#orthology", "database": "AGR" }, { "id": "MGI:1917416", "url": "https://alliancegenome.org/gene/MGI:1917416#orthology", "database": "AGR" }, { "id": "MGI:1914967", "url": "https://alliancegenome.org/gene/MGI:1914967#orthology", "database": "AGR" }, { "id": "MGI:3644466", "url": "https://alliancegenome.org/gene/MGI:3644466#orthology", "database": "AGR" }, { "id": "MGI:96789", "url": "https://alliancegenome.org/gene/MGI:96789#orthology", "database": "AGR" }, { "id": "RGD:1304912", "url": "https://alliancegenome.org/gene/RGD:1304912#orthology", "database": "AGR" }, { "id": "RGD:1565682", "url": "https://alliancegenome.org/gene/RGD:1565682#orthology", "database": "AGR" }, { "id": "RGD:1309724", "url": "https://alliancegenome.org/gene/RGD:1309724#orthology", "database": "AGR" }, { "id": "RGD:3008", "url": "https://alliancegenome.org/gene/RGD:3008#orthology", "database": "AGR" }, { "id": "RGD:1560354", "url": "https://alliancegenome.org/gene/RGD:1560354#orthology", "database": "AGR" }, { "id": "RGD:2321667", "url": "https://alliancegenome.org/gene/RGD:2321667#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VBK6-1", "protein_name": "Lipase", "gene_name": "CG5990", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNRFTGSLLVLVALAVGVYSAAIDGPIDFYKLYDNPEAHISLKSKITTADRTAAHGYPSEHHHIVTEDGYILGVFRIPYSHKLQNQNEKRPIVLLQHGLTSCSDAWILQGPNDGLPYLLADAGFDVWMGNARGTSYSRNHTTLSPDHPNFWKFSWHEIGIYDITAIIDYALSTENGQGQDAIHYVGHSQGTTVFFALMSWIPEYNDKIKTAHMFAPVAIMKNLSSGLVRSVGPYLGHRNTYSVLFGSQEFLPHNEFLMAIFFNICQPDFMLRPVCESAMEKLYAGGRVNMTAMPEGMATHPAGCSTDQMLHYLQEQQSGYFRLFDHGTKKNLEVYGTQEPPEYPVELINSLVHMWYADSDNLAAVEDVEQIAERLPNKVMHRMADTEWNHGDFALNWEVRKYINEPVIDIMMEYELKNIGT", "length": 421 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" }, { "id": "RGD:708441", "url": "https://alliancegenome.org/gene/RGD:708441#orthology", "database": "AGR" }, { "id": "MGI:2679259", "url": "https://alliancegenome.org/gene/MGI:2679259#orthology", "database": "AGR" }, { "id": "MGI:1926003", "url": "https://alliancegenome.org/gene/MGI:1926003#orthology", "database": "AGR" }, { "id": "MGI:3779637", "url": "https://alliancegenome.org/gene/MGI:3779637#orthology", "database": "AGR" }, { "id": "MGI:3647308", "url": "https://alliancegenome.org/gene/MGI:3647308#orthology", "database": "AGR" }, { "id": "MGI:3647649", "url": "https://alliancegenome.org/gene/MGI:3647649#orthology", "database": "AGR" }, { "id": "MGI:1917416", "url": "https://alliancegenome.org/gene/MGI:1917416#orthology", "database": "AGR" }, { "id": "MGI:1914967", "url": "https://alliancegenome.org/gene/MGI:1914967#orthology", "database": "AGR" }, { "id": "MGI:3644466", "url": "https://alliancegenome.org/gene/MGI:3644466#orthology", "database": "AGR" }, { "id": "MGI:96789", "url": "https://alliancegenome.org/gene/MGI:96789#orthology", "database": "AGR" }, { "id": "RGD:1304912", "url": "https://alliancegenome.org/gene/RGD:1304912#orthology", "database": "AGR" }, { "id": "RGD:1565682", "url": "https://alliancegenome.org/gene/RGD:1565682#orthology", "database": "AGR" }, { "id": "RGD:1309724", "url": "https://alliancegenome.org/gene/RGD:1309724#orthology", "database": "AGR" }, { "id": "RGD:3008", "url": "https://alliancegenome.org/gene/RGD:3008#orthology", "database": "AGR" }, { "id": "RGD:1560354", "url": "https://alliancegenome.org/gene/RGD:1560354#orthology", "database": "AGR" }, { "id": "RGD:2321667", "url": "https://alliancegenome.org/gene/RGD:2321667#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VG46-1", "protein_name": "Lipase", "gene_name": "Dmel\\CG6753", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRRERVVLLCLALLGLQQVSRATLRQSREIIITDAVRRIQNDGYNVERHSVTTKDGYVLTLHRIPQVDPELGSLLRRPVVFLLSGLYASSDVWLLNGREDSLAYLLWRAGYDVWLGNNRGNIYCRKNMWRNTTEREFWDFSWHEMGVYDLPAQVDYVLRTTGQKAMHFVGISQGGTVFLVLNSMMPQYNAVFKSATLLAPVAYVSNTKSGLAKVIGPVLGTRNYVSKMLEGVEMFSTNKFFKKFLSMTCLENEKPLVCISRLWPAVGYDTRFLNKTLLPDLMANFPAGGSVKQLMHYFQGYVSTRFRQYDYGPERNWLHYQQLEPPEYALENVSTPVTVFFSENDYIVAPADIWRLLTRLPNVEAVYKVPWKRWNHFDFICGLGVREYIFDNIVLSMNRYEQRRR", "length": 405 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" }, { "id": "RGD:708441", "url": "https://alliancegenome.org/gene/RGD:708441#orthology", "database": "AGR" }, { "id": "MGI:2679259", "url": "https://alliancegenome.org/gene/MGI:2679259#orthology", "database": "AGR" }, { "id": "MGI:1926003", "url": "https://alliancegenome.org/gene/MGI:1926003#orthology", "database": "AGR" }, { "id": "MGI:3779637", "url": "https://alliancegenome.org/gene/MGI:3779637#orthology", "database": "AGR" }, { "id": "MGI:3647308", "url": "https://alliancegenome.org/gene/MGI:3647308#orthology", "database": "AGR" }, { "id": "MGI:3647649", "url": "https://alliancegenome.org/gene/MGI:3647649#orthology", "database": "AGR" }, { "id": "MGI:1917416", "url": "https://alliancegenome.org/gene/MGI:1917416#orthology", "database": "AGR" }, { "id": "MGI:1914967", "url": "https://alliancegenome.org/gene/MGI:1914967#orthology", "database": "AGR" }, { "id": "MGI:3644466", "url": "https://alliancegenome.org/gene/MGI:3644466#orthology", "database": "AGR" }, { "id": "MGI:96789", "url": "https://alliancegenome.org/gene/MGI:96789#orthology", "database": "AGR" }, { "id": "RGD:1304912", "url": "https://alliancegenome.org/gene/RGD:1304912#orthology", "database": "AGR" }, { "id": "RGD:1565682", "url": "https://alliancegenome.org/gene/RGD:1565682#orthology", "database": "AGR" }, { "id": "RGD:1309724", "url": "https://alliancegenome.org/gene/RGD:1309724#orthology", "database": "AGR" }, { "id": "RGD:3008", "url": "https://alliancegenome.org/gene/RGD:3008#orthology", "database": "AGR" }, { "id": "RGD:1560354", "url": "https://alliancegenome.org/gene/RGD:1560354#orthology", "database": "AGR" }, { "id": "RGD:2321667", "url": "https://alliancegenome.org/gene/RGD:2321667#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VG47-1", "protein_name": "Lipase", "gene_name": "Dmel\\CG11608", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MQSFLIQMLPILLGIFFVWLSNSTALSEVNWKNHSLHRIHHRTKVITAVDIISSHNYPVQTHTVVTRDGYILSVFRIPSSQLCASSEPKPVVLINHGMTGSADSWLLTGPRNGLPFLLADACYDVWLINCRGTRYSRKHLKLKAWLLQFWRFSWHEIGMEDLPATVDHILASTKRNSLHYVGHSQGCTSMLVMLSMRPEYNKRIRTTILLAPPVFLKHSLSMGHKIMKPLFNLLPDIELLPHHKMLNSAVSAICKILGVKDVCTALYLLTNGRVSQHMNRTLIPMLIATHPAGISSRQPRHFFQLKDSGRFRQYDFGFGMNYLIYRQNTPPEYPLEMVRPHSAIHIFYSDDDGTISPRDVLTLASKLPYAVPHHITDETWNHMDFLLANNINELINNPVIKIIKTFEENIKHKIGNIKGEISIDALLNEF", "length": 430 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" }, { "id": "RGD:708441", "url": "https://alliancegenome.org/gene/RGD:708441#orthology", "database": "AGR" }, { "id": "MGI:2679259", "url": "https://alliancegenome.org/gene/MGI:2679259#orthology", "database": "AGR" }, { "id": "MGI:1926003", "url": "https://alliancegenome.org/gene/MGI:1926003#orthology", "database": "AGR" }, { "id": "MGI:3779637", "url": "https://alliancegenome.org/gene/MGI:3779637#orthology", "database": "AGR" }, { "id": "MGI:3647308", "url": "https://alliancegenome.org/gene/MGI:3647308#orthology", "database": "AGR" }, { "id": "MGI:3647649", "url": "https://alliancegenome.org/gene/MGI:3647649#orthology", "database": "AGR" }, { "id": "MGI:1917416", "url": "https://alliancegenome.org/gene/MGI:1917416#orthology", "database": "AGR" }, { "id": "MGI:1914967", "url": "https://alliancegenome.org/gene/MGI:1914967#orthology", "database": "AGR" }, { "id": "MGI:3644466", "url": "https://alliancegenome.org/gene/MGI:3644466#orthology", "database": "AGR" }, { "id": "MGI:96789", "url": "https://alliancegenome.org/gene/MGI:96789#orthology", "database": "AGR" }, { "id": "RGD:1304912", "url": "https://alliancegenome.org/gene/RGD:1304912#orthology", "database": "AGR" }, { "id": "RGD:1565682", "url": "https://alliancegenome.org/gene/RGD:1565682#orthology", "database": "AGR" }, { "id": "RGD:1309724", "url": "https://alliancegenome.org/gene/RGD:1309724#orthology", "database": "AGR" }, { "id": "RGD:3008", "url": "https://alliancegenome.org/gene/RGD:3008#orthology", "database": "AGR" }, { "id": "RGD:1560354", "url": "https://alliancegenome.org/gene/RGD:1560354#orthology", "database": "AGR" }, { "id": "RGD:2321667", "url": "https://alliancegenome.org/gene/RGD:2321667#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VG48-1", "protein_name": "Lipase", "gene_name": "Dmel\\CG11600", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLLMELVIFFDWLLIVSGMPKVKFGLQNFTGRGKDYRIKVITGILIIDKYGYSVETHTVRTGDGYILDMFRIPSSPNCKEDGFKPSVLIQHGLISLADSFLVTGPRSGLPFMLADRCYDVWLSNSRGVRYSQRHIRLKASQDAFWRFSWHEMGMEDLPAMIDYILSTTNEEALHFVCHSQGCTTLLVLLSMKPEYNRMIKTANMMAPAVFMKHARNKLMKMFGNIIMSMKDSSFFGPLDAIRFLLSVFCKCSKFKKLCAFMFILASEEPTSYMNNTAIPLILATHPGAISTRQPKHFLQLRKSGKFRPYDFGVMRNKKLYNQDTPPDYPLENVRPQSPIHIYHSHGDDLVARKDIHILISKLDKAVLHDVVFEKWSHSDFLFAKLIKKVVNEPIIKVIDHFENRQQ", "length": 406 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" }, { "id": "RGD:708441", "url": "https://alliancegenome.org/gene/RGD:708441#orthology", "database": "AGR" }, { "id": "MGI:2679259", "url": "https://alliancegenome.org/gene/MGI:2679259#orthology", "database": "AGR" }, { "id": "MGI:1926003", "url": "https://alliancegenome.org/gene/MGI:1926003#orthology", "database": "AGR" }, { "id": "MGI:3779637", "url": "https://alliancegenome.org/gene/MGI:3779637#orthology", "database": "AGR" }, { "id": "MGI:3647308", "url": "https://alliancegenome.org/gene/MGI:3647308#orthology", "database": "AGR" }, { "id": "MGI:3647649", "url": "https://alliancegenome.org/gene/MGI:3647649#orthology", "database": "AGR" }, { "id": "MGI:1917416", "url": "https://alliancegenome.org/gene/MGI:1917416#orthology", "database": "AGR" }, { "id": "MGI:1914967", "url": "https://alliancegenome.org/gene/MGI:1914967#orthology", "database": "AGR" }, { "id": "MGI:3644466", "url": "https://alliancegenome.org/gene/MGI:3644466#orthology", "database": "AGR" }, { "id": "MGI:96789", "url": "https://alliancegenome.org/gene/MGI:96789#orthology", "database": "AGR" }, { "id": "RGD:1304912", "url": "https://alliancegenome.org/gene/RGD:1304912#orthology", "database": "AGR" }, { "id": "RGD:1565682", "url": "https://alliancegenome.org/gene/RGD:1565682#orthology", "database": "AGR" }, { "id": "RGD:1309724", "url": "https://alliancegenome.org/gene/RGD:1309724#orthology", "database": "AGR" }, { "id": "RGD:3008", "url": "https://alliancegenome.org/gene/RGD:3008#orthology", "database": "AGR" }, { "id": "RGD:1560354", "url": "https://alliancegenome.org/gene/RGD:1560354#orthology", "database": "AGR" }, { "id": "RGD:2321667", "url": "https://alliancegenome.org/gene/RGD:2321667#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VG50-1", "protein_name": "Lipase", "gene_name": "CG12294", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPYKTLVILSVCTQIVNGITSAEIIASHNYPVEIHTVVTRDGYLLNAFRIPNSIYCEQSGTKPAVLFQHGMTASSDVFLVNGPRDALPFMLADACFDVWLSNSRGTRYSRRHVSLDPSDEDFWRFSWHEIGTEDVAAFIDYILGTTNQSAVHYVGHSQGCTTLVVLLSMRPEYNQFVKTAILLGPPVFMGHTHTLGQIFLRTLIMSMPDCEFMFHNRILNKILRRICGLFVVRVYCSTFFMIVNGKFSDHLNTSAIPLIAATLPAGVSSRQPKHFIQLTDSGRFRPFDFGILRNLINYRSLTPPDYPLHNVRPLTPVHIFYSDDDLSAAKEDVENFATSLPEAVMHRISTPSWHHMDFVHSMTVANVINKPVIEIFKRFEQPIDCKGSL", "length": 389 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" }, { "id": "RGD:708441", "url": "https://alliancegenome.org/gene/RGD:708441#orthology", "database": "AGR" }, { "id": "RGD:1304912", "url": "https://alliancegenome.org/gene/RGD:1304912#orthology", "database": "AGR" }, { "id": "RGD:1565682", "url": "https://alliancegenome.org/gene/RGD:1565682#orthology", "database": "AGR" }, { "id": "RGD:1309724", "url": "https://alliancegenome.org/gene/RGD:1309724#orthology", "database": "AGR" }, { "id": "RGD:3008", "url": "https://alliancegenome.org/gene/RGD:3008#orthology", "database": "AGR" }, { "id": "RGD:1560354", "url": "https://alliancegenome.org/gene/RGD:1560354#orthology", "database": "AGR" }, { "id": "RGD:2321667", "url": "https://alliancegenome.org/gene/RGD:2321667#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VKR5-1", "protein_name": "Lipase", "gene_name": "Lip2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGGSGCIGAIKVMLIVCAIGRNAHSSPPESRYKWTTMDWLEAQNVSHEVHNVTTADGYQLQLQRLPRLGAKPVLLVHGLLGSSLGWVCMGPERSLAFQLHHREYDVWLANLRGVSPYGRQHIDLTDVMVEFWRFSFHEHGAYDLPAIIDHMAKVTGGEQLASRGGPGQDEEQIHHQVVLIGHSQAFNAFLVLCAVHPRFNQRIQLIQALAPLARLHRQVRFDSFQVRRLMKFIKKRQKAYKFEIFPPGYFRKVCQAKRDLCEYYAKQLVGSAQNNKKLLEAFNYEYLLQGGSPREIKHLQQIWKSGDFISYDFGTAENLQVYHSVEALSYNISQITVPIILYFGETDAIATPEGVHAIYARMLRSVKSVRRINSKKFNHLDFLISGDVKSLVNDKLIEHMEQFFDGRLPYVIE", "length": 413 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VKS5-1", "protein_name": "Partial AB-hydrolase lipase domain-containing protein", "gene_name": "CG17099", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRSTVEVKGRLLLTLLLHCLVALEVCGRAGAFTLLSPFSYSSLSFKNLLNSVLLSSNPNLAGGGRNLKSDVLEDASLITPKLIRKYGYPSETHTVVTKDGYILEMHRIPKKGAQPVLLMHGILDTSATWVLMGPKSGLGYMLSDLGYDVWMGNSRGNRYSKNHTSLNSDYQEFWDFTFHEMGKYDLPANIDYILSKTGYEQVHYIGHSQGTAIFWVLCSEQPAYTQKITSMHALAPIAYIHDMKSPLFRTLVLFLDFLTAATRMLRITEFMPNTKFLVDHSQVVCHDNAMTQDVCSNILFLVAGYNSEQLNKTMLPVMLSHTPSGASIKQLEHFGQLMKSGHFRKFDRGYLRNQLEYNRMTPPDYDLSRVKVPVALYYSVNDLLVSTTGVDRLARELPNVIDKYLVPMERFNHLDFLWAIDVKPLVYNRLVRNVRRVENHRAKLTANLANYLAMQLQRQQLRQQMQQQMMEGLPPNVHLPHGLGMEMLARATTFAPVTHPTTTMTMPTTTTENDAEDEVLTTAATATEVPA", "length": 531 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" }, { "id": "RGD:708441", "url": "https://alliancegenome.org/gene/RGD:708441#orthology", "database": "AGR" }, { "id": "MGI:2679259", "url": "https://alliancegenome.org/gene/MGI:2679259#orthology", "database": "AGR" }, { "id": "MGI:1926003", "url": "https://alliancegenome.org/gene/MGI:1926003#orthology", "database": "AGR" }, { "id": "MGI:3779637", "url": "https://alliancegenome.org/gene/MGI:3779637#orthology", "database": "AGR" }, { "id": "MGI:3647308", "url": "https://alliancegenome.org/gene/MGI:3647308#orthology", "database": "AGR" }, { "id": "MGI:3647649", "url": "https://alliancegenome.org/gene/MGI:3647649#orthology", "database": "AGR" }, { "id": "MGI:1917416", "url": "https://alliancegenome.org/gene/MGI:1917416#orthology", "database": "AGR" }, { "id": "MGI:1914967", "url": "https://alliancegenome.org/gene/MGI:1914967#orthology", "database": "AGR" }, { "id": "MGI:3644466", "url": "https://alliancegenome.org/gene/MGI:3644466#orthology", "database": "AGR" }, { "id": "MGI:96789", "url": "https://alliancegenome.org/gene/MGI:96789#orthology", "database": "AGR" }, { "id": "RGD:1304912", "url": "https://alliancegenome.org/gene/RGD:1304912#orthology", "database": "AGR" }, { "id": "RGD:1565682", "url": "https://alliancegenome.org/gene/RGD:1565682#orthology", "database": "AGR" }, { "id": "RGD:1309724", "url": "https://alliancegenome.org/gene/RGD:1309724#orthology", "database": "AGR" }, { "id": "RGD:3008", "url": "https://alliancegenome.org/gene/RGD:3008#orthology", "database": "AGR" }, { "id": "RGD:1560354", "url": "https://alliancegenome.org/gene/RGD:1560354#orthology", "database": "AGR" }, { "id": "RGD:2321667", "url": "https://alliancegenome.org/gene/RGD:2321667#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VKS9-1", "protein_name": "Partial AB-hydrolase lipase domain-containing protein", "gene_name": "Acp", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAIAFNIAIYAIILVGSLVPSKTQEWVPYAYPVDENQGLNEQTQWQSQSQIQSQGTSQSQSQAQIQSQPEPRSCLQCQQASYQQFFAEVDIQIDAKLETPKMISKYGHQVETHYAFTADGYKLCLHRIPRSGATPVLLVHGLMASSATWVQFGPSQGLAYILSQSGYDVWMLNTRGNVYSEERLAGRESDKIFWDFSFHEIGQYDLPAAIDLILLQTKMPSIQYIGHSQGSTAFFVMCSERPEYAGKISLMQSLSPSVYMEGTRSPALKFMKLFSGGFTMLLNLLGGHKISLKNKIVDMFRNHICTKLIPSRICAIFEFVVCGFNFNSFNMTLSPILEGHASQGSSAKQIYHFAQLQGNSAFQKYDYGLILNKIRYQSIFPPLYNLSLALGKVALHRGDGDWLGSESDVLRLERDLPNCIENRNIRFEGFSHFDFTISKDVRSLVYDRVISLCGSNR", "length": 457 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" }, { "id": "RGD:708441", "url": "https://alliancegenome.org/gene/RGD:708441#orthology", "database": "AGR" }, { "id": "MGI:2679259", "url": "https://alliancegenome.org/gene/MGI:2679259#orthology", "database": "AGR" }, { "id": "MGI:1926003", "url": "https://alliancegenome.org/gene/MGI:1926003#orthology", "database": "AGR" }, { "id": "MGI:3779637", "url": "https://alliancegenome.org/gene/MGI:3779637#orthology", "database": "AGR" }, { "id": "MGI:3647308", "url": "https://alliancegenome.org/gene/MGI:3647308#orthology", "database": "AGR" }, { "id": "MGI:3647649", "url": "https://alliancegenome.org/gene/MGI:3647649#orthology", "database": "AGR" }, { "id": "MGI:1917416", "url": "https://alliancegenome.org/gene/MGI:1917416#orthology", "database": "AGR" }, { "id": "MGI:1914967", "url": "https://alliancegenome.org/gene/MGI:1914967#orthology", "database": "AGR" }, { "id": "MGI:3644466", "url": "https://alliancegenome.org/gene/MGI:3644466#orthology", "database": "AGR" }, { "id": "MGI:96789", "url": "https://alliancegenome.org/gene/MGI:96789#orthology", "database": "AGR" }, { "id": "RGD:1304912", "url": "https://alliancegenome.org/gene/RGD:1304912#orthology", "database": "AGR" }, { "id": "RGD:1565682", "url": "https://alliancegenome.org/gene/RGD:1565682#orthology", "database": "AGR" }, { "id": "RGD:1309724", "url": "https://alliancegenome.org/gene/RGD:1309724#orthology", "database": "AGR" }, { "id": "RGD:3008", "url": "https://alliancegenome.org/gene/RGD:3008#orthology", "database": "AGR" }, { "id": "RGD:1560354", "url": "https://alliancegenome.org/gene/RGD:1560354#orthology", "database": "AGR" }, { "id": "RGD:2321667", "url": "https://alliancegenome.org/gene/RGD:2321667#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VKT1-1", "protein_name": "Partial AB-hydrolase lipase domain-containing protein", "gene_name": "CG17093", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MQLGFLYAFVALLAIFRVEPSEGIIDINNQLNNIISPPILPAVESILDINGDADSTEDEQKVRLQRESIVKDYGFVFKPQPIVLESNSSYKPSVESEGQAQSFSRGLEEAKLQIQKQSQSQSQAQGLGQSQQQIQYANIARTKVQKQFQSQQLGLAQSQQQTQIQQSLNQDGAKLREKPYPHIQTSSQRNADDPESEEAEAPGGLSGKIALVPPNEEGDQKQDQAQSQIEDEAEVLRQGLAQTESQIQNQRQGLEKEIQGQSQSQDQAQSQDEAINPESANAENRSSQQSGDVAENQDQAESQAQERSQLQLEGQEQSQDQAQSQDQSQALEKGGAPPLSPQQSLVQAEDQAQEDPIDQSLHQAQSEVLNQVKSQTNGQLKAQAQMQAQVLDQALEDAHVQYQSQAQSQGISLSQTTQQSLVEPDDQAKEDPVDQSLHQAQSEIIKQLLSQTNDQDKAQAQAQAQTLDQALEEAHVQYQSQTQAQGTPIFQPPQLQPEDRDQDTALDQSPTQAQLDAQSQSQEQANTKLQRKSQAQSEAHGIILTTLRKAQAQQQSEVQSPQQEPLRSDDQSGDQAGDVAQNTALDQSLHQAQAEVQEQLQSQTQASGTSLTQSQQQSQVQAVEALAQSLTQAHAQIQEQAQSQSQSQEQDQSQSQAPNERQSQLQSQRQDQDQGPKFDDDLDEQPAPRSCSQCQKASYPQYITEVDIEIDAKLDTPKMISKYGHQAETHYAFTADGYKLCLHRIPRSGATPVLLVHGLMASSDTWVQFGPSQGLAYILSQSGYDVWMLNTRGNVYSEERLAGRESDKIFWDFSFHEIGQYDLPAAIDLILLQTKMPSIQYIGHSQGSTAFFVMCSERPEYAGKISLMQSLSPSVYMEGTRSPALKFMKVLQGGFTMLLNLLGGHKISLKNRIVDMFRNHICNKLIPSRICAIFEFVVCGFNFNSFNMTLSPILEGHASQGSSAKQIYHFAQLQGNSAFQKYDYGLILNKIRYQSIFPPLYNLSLALGKVALHRGDGDWLGSESDVLRLERDLPNCIENRNIRFEGFSHFDFTISKDVRSLVYDRVIDLCGSN", "length": 1073 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VKT2-1", "protein_name": "AB hydrolase-1 domain-containing protein", "gene_name": "Dmel\\CG7329", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPHAICILVVLGIYTLDGSGVLGGFMENTYPASVIEDAHLNTIQLLEKYKHPAETHQVTTDDKYILTLHRIARPGAKPVLLVHGLEDTSSTWIVMGPESGLGYFLYANGYDVWMGNVRGNRYSKGHVKLNPNTDKSYWSFSWHEIGMYDLPAMIDGVLQKTGYQKLSYFGHSQGTTSFFVMASSRPEYNAKIHLMSALAPVAFMKHMKAPLMGIARMGMNMFGDNFELFPHSEVFLNQCLSSAAMLKTCMRFYWQIVGKNREEQNMTMFPVVLGHLPGGCNIKQALHYLQMQKSDRFCQYDYESKENQRLYGRSTPPDYRLERIKAPVALYYGSNDYLSAVEDVHRLAKVLPNVVENHLYRKWNHMDMIWGISARRSIQPRILQVMQYWETGGGGTKDGTTGSPVEEDVPQLTTETPIEEGTTQGDEKIGNVQGNEEQGHAEETEQVQVTTSPTSEL", "length": 457 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" }, { "id": "RGD:708441", "url": "https://alliancegenome.org/gene/RGD:708441#orthology", "database": "AGR" }, { "id": "MGI:2679259", "url": "https://alliancegenome.org/gene/MGI:2679259#orthology", "database": "AGR" }, { "id": "MGI:1926003", "url": "https://alliancegenome.org/gene/MGI:1926003#orthology", "database": "AGR" }, { "id": "MGI:3779637", "url": "https://alliancegenome.org/gene/MGI:3779637#orthology", "database": "AGR" }, { "id": "MGI:3647308", "url": "https://alliancegenome.org/gene/MGI:3647308#orthology", "database": "AGR" }, { "id": "MGI:3647649", "url": "https://alliancegenome.org/gene/MGI:3647649#orthology", "database": "AGR" }, { "id": "MGI:1917416", "url": "https://alliancegenome.org/gene/MGI:1917416#orthology", "database": "AGR" }, { "id": "MGI:1914967", "url": "https://alliancegenome.org/gene/MGI:1914967#orthology", "database": "AGR" }, { "id": "MGI:3644466", "url": "https://alliancegenome.org/gene/MGI:3644466#orthology", "database": "AGR" }, { "id": "MGI:96789", "url": "https://alliancegenome.org/gene/MGI:96789#orthology", "database": "AGR" }, { "id": "RGD:1304912", "url": "https://alliancegenome.org/gene/RGD:1304912#orthology", "database": "AGR" }, { "id": "RGD:1565682", "url": "https://alliancegenome.org/gene/RGD:1565682#orthology", "database": "AGR" }, { "id": "RGD:1309724", "url": "https://alliancegenome.org/gene/RGD:1309724#orthology", "database": "AGR" }, { "id": "RGD:3008", "url": "https://alliancegenome.org/gene/RGD:3008#orthology", "database": "AGR" }, { "id": "RGD:1560354", "url": "https://alliancegenome.org/gene/RGD:1560354#orthology", "database": "AGR" }, { "id": "RGD:2321667", "url": "https://alliancegenome.org/gene/RGD:2321667#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VKT7-1", "protein_name": "Lipase", "gene_name": "Dmel\\CG18302", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLKSCHLNYCYGILISLFIFCDTASGDLIKVDKTILEDANLITPDLIKKYGYPAETHKIQAKDGFVLTAHRIPKPGGQPVLLVHGLLDSSVAYVILGPERSLGFLLSDMGYDVWLLNTRGNRYSRKHKRYHRYQPQFWDFSFHELGVYDLPAAIDYVLARSKDFEQIHYVGHSQGTTSFFVMGSERSAYMKKIKLMQALAPVVFWDYIDSPIILTFVKYLRPLVFIARSFGIYEFPPENEVWRSLIHKICSFVFQNTCTYFLMEAMGVDYAQFNSSLLPLFTGHASSGSSVKSLEHYGQQIHSGGFFKYNYYSTWENRRNHGVDTPPQYKLTNVDCKVALYYSRNDRLTSDKDVVRLRDILPNVVLDYMFPDPLYNHINFIWGNDVKTVLNDRMIELMRKVDNGEV", "length": 406 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" }, { "id": "RGD:708441", "url": "https://alliancegenome.org/gene/RGD:708441#orthology", "database": "AGR" }, { "id": "MGI:2679259", "url": "https://alliancegenome.org/gene/MGI:2679259#orthology", "database": "AGR" }, { "id": "MGI:1926003", "url": "https://alliancegenome.org/gene/MGI:1926003#orthology", "database": "AGR" }, { "id": "MGI:3779637", "url": "https://alliancegenome.org/gene/MGI:3779637#orthology", "database": "AGR" }, { "id": "MGI:3647308", "url": "https://alliancegenome.org/gene/MGI:3647308#orthology", "database": "AGR" }, { "id": "MGI:3647649", "url": "https://alliancegenome.org/gene/MGI:3647649#orthology", "database": "AGR" }, { "id": "MGI:1917416", "url": "https://alliancegenome.org/gene/MGI:1917416#orthology", "database": "AGR" }, { "id": "MGI:1914967", "url": "https://alliancegenome.org/gene/MGI:1914967#orthology", "database": "AGR" }, { "id": "MGI:3644466", "url": "https://alliancegenome.org/gene/MGI:3644466#orthology", "database": "AGR" }, { "id": "MGI:96789", "url": "https://alliancegenome.org/gene/MGI:96789#orthology", "database": "AGR" }, { "id": "RGD:1304912", "url": "https://alliancegenome.org/gene/RGD:1304912#orthology", "database": "AGR" }, { "id": "RGD:1565682", "url": "https://alliancegenome.org/gene/RGD:1565682#orthology", "database": "AGR" }, { "id": "RGD:1309724", "url": "https://alliancegenome.org/gene/RGD:1309724#orthology", "database": "AGR" }, { "id": "RGD:3008", "url": "https://alliancegenome.org/gene/RGD:3008#orthology", "database": "AGR" }, { "id": "RGD:1560354", "url": "https://alliancegenome.org/gene/RGD:1560354#orthology", "database": "AGR" }, { "id": "RGD:2321667", "url": "https://alliancegenome.org/gene/RGD:2321667#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VKT8-1", "protein_name": "Lipase", "gene_name": "Dmel\\CG18301", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSLSSSSKFLIWTFFLGLFQLEANAFFNPFQLAIPSSVLEDAHLNTIQLISKYGYPAENYTVQSDDGYLLGLFRIARPGALPVLLVHGLMDSSDTWVMMGPSSSLGYMLYEQGYDVWMANVRGNTYTKRHVRYSAEDSDFWNFSFHEMGIFDLPAIIDYILMQSGFGQLHYIGHSQGSTIFWILASERPEYMEKIVMMQALAPVAFLSHCRSPIVNLLASQDTAVASFLSAAGYNEFLPSNSVIDQFKRYACRDIISSSVCQSLFFILFGFNGQQVNQTMLPIVVGHTPAGASIRQMHHYGQLRNSGKFQQFDYGLLNFLHYGSLSPPPYELEKVKAKVAIYYAKNDWIAPPEDVDMLFNRLPNVVEKYLVPNENFNHFDLVWGRDAKRILWNRMLGVMQSVVPYSSYNDGDSITTVFVNRF", "length": 422 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" }, { "id": "RGD:708441", "url": "https://alliancegenome.org/gene/RGD:708441#orthology", "database": "AGR" }, { "id": "MGI:2679259", "url": "https://alliancegenome.org/gene/MGI:2679259#orthology", "database": "AGR" }, { "id": "MGI:1926003", "url": "https://alliancegenome.org/gene/MGI:1926003#orthology", "database": "AGR" }, { "id": "MGI:3779637", "url": "https://alliancegenome.org/gene/MGI:3779637#orthology", "database": "AGR" }, { "id": "MGI:3647308", "url": "https://alliancegenome.org/gene/MGI:3647308#orthology", "database": "AGR" }, { "id": "MGI:3647649", "url": "https://alliancegenome.org/gene/MGI:3647649#orthology", "database": "AGR" }, { "id": "MGI:1917416", "url": "https://alliancegenome.org/gene/MGI:1917416#orthology", "database": "AGR" }, { "id": "MGI:1914967", "url": "https://alliancegenome.org/gene/MGI:1914967#orthology", "database": "AGR" }, { "id": "MGI:3644466", "url": "https://alliancegenome.org/gene/MGI:3644466#orthology", "database": "AGR" }, { "id": "MGI:96789", "url": "https://alliancegenome.org/gene/MGI:96789#orthology", "database": "AGR" }, { "id": "RGD:1304912", "url": "https://alliancegenome.org/gene/RGD:1304912#orthology", "database": "AGR" }, { "id": "RGD:1565682", "url": "https://alliancegenome.org/gene/RGD:1565682#orthology", "database": "AGR" }, { "id": "RGD:1309724", "url": "https://alliancegenome.org/gene/RGD:1309724#orthology", "database": "AGR" }, { "id": "RGD:3008", "url": "https://alliancegenome.org/gene/RGD:3008#orthology", "database": "AGR" }, { "id": "RGD:1560354", "url": "https://alliancegenome.org/gene/RGD:1560354#orthology", "database": "AGR" }, { "id": "RGD:2321667", "url": "https://alliancegenome.org/gene/RGD:2321667#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VQQ5-1", "protein_name": "Lipase", "gene_name": "Dmel\\CG2772", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLAKVLTILAIVASAGAADDFDPFIDIPFKRLKTSAERIAEHGYPAESHFVETPDGYVLNVFRIPHSPKLNSNGNEGESEASRPVVLIMHGLFSCSDCFLLNGPEDALPYNYADAGYDVWLGNARGNIYSRNNTRLNVKHPYFWKFSWHEIGSIDLPATIDYILAETGQQSLHYVGHSQGCTSFFVMGSYRPEYNAKIKTAHMLAPPVYMGNSTEGLIVSTAPLFGHHGIGSTLLENQVLLPQNAFIQRVLDTTCSNQPIMLSYCKTLAILWGGPEIGNLNQTLLPQIAETHPAGVSSNQAIHYIQSYASNDFRLYDWGSKRNLEYYGVSEPPAYDLTKITSELYLYYGLADGSANKQDISRLPDLLPNLALLHEVPDSTWGHLDFIFATEVKRVINDLVLDYSKAYDARETNNEI", "length": 416 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" }, { "id": "RGD:708441", "url": "https://alliancegenome.org/gene/RGD:708441#orthology", "database": "AGR" }, { "id": "MGI:2679259", "url": "https://alliancegenome.org/gene/MGI:2679259#orthology", "database": "AGR" }, { "id": "MGI:1926003", "url": "https://alliancegenome.org/gene/MGI:1926003#orthology", "database": "AGR" }, { "id": "MGI:3779637", "url": "https://alliancegenome.org/gene/MGI:3779637#orthology", "database": "AGR" }, { "id": "MGI:3647308", "url": "https://alliancegenome.org/gene/MGI:3647308#orthology", "database": "AGR" }, { "id": "MGI:3647649", "url": "https://alliancegenome.org/gene/MGI:3647649#orthology", "database": "AGR" }, { "id": "MGI:1917416", "url": "https://alliancegenome.org/gene/MGI:1917416#orthology", "database": "AGR" }, { "id": "MGI:1914967", "url": "https://alliancegenome.org/gene/MGI:1914967#orthology", "database": "AGR" }, { "id": "MGI:3644466", "url": "https://alliancegenome.org/gene/MGI:3644466#orthology", "database": "AGR" }, { "id": "MGI:96789", "url": "https://alliancegenome.org/gene/MGI:96789#orthology", "database": "AGR" }, { "id": "RGD:1304912", "url": "https://alliancegenome.org/gene/RGD:1304912#orthology", "database": "AGR" }, { "id": "RGD:1565682", "url": "https://alliancegenome.org/gene/RGD:1565682#orthology", "database": "AGR" }, { "id": "RGD:1309724", "url": "https://alliancegenome.org/gene/RGD:1309724#orthology", "database": "AGR" }, { "id": "RGD:3008", "url": "https://alliancegenome.org/gene/RGD:3008#orthology", "database": "AGR" }, { "id": "RGD:1560354", "url": "https://alliancegenome.org/gene/RGD:1560354#orthology", "database": "AGR" }, { "id": "RGD:2321667", "url": "https://alliancegenome.org/gene/RGD:2321667#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Z0M5-1", "protein_name": "Lysosomal acid lipase/cholesteryl ester hydrolase", "gene_name": "Lipa", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQLQGLVFVFTIGILLSRVPTGTVSAVDPEVNMNVTEIIMRWGYPGEEHSVLTGDGYILSIHRIPRGRKNHFGKGPRPVVYLQHGLLADSSNWVTNIDNSSLGFLLADAGFDVWMGNSRGNTWSLKHKTLSVSQDEFWAFSFDEMAKYDLPASINYILNKTGQEQIYYVGHSQGCTIGFIAFSQMPELAKKIKMFLVLAPVLSLNFASGPLLQLGRLPDPLLKDMFGQKQFLPQSAMLKWLSIHVCTHVIMKELCANVFFLLCGFNEKNLNMSRVDVYTTHCPAGTSVQNMLHWGQVFKYRKLQAFDWGSSEKNYFHYNQSFPPSYNIKNMRLPTALWSGGRDWLADINDITILLTQIPKLVYHKNIPEWDHLDFIWGLDAPWKLYDEIISLMKKYQ", "length": 397 }, "evidence": [ { "id": "MGI:96789", "url": "https://alliancegenome.org/gene/MGI:96789#orthology", "database": "AGR" }, { "id": "FB:FBgn0036996", "url": "https://alliancegenome.org/gene/FB:FBgn0036996#orthology", "database": "AGR" }, { "id": "RGD:3008", "url": "https://alliancegenome.org/gene/RGD:3008#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "sterol ester esterase activity", "id": "GO:0004771", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004771", "evidence": [ { "database": "UniProtKB", "id": "Q9VPE9", "url": "https://www.uniprot.org/uniprotkb/Q9VPE9" } ], "pmid": "" }, { "name": "lipase activity", "id": "GO:0016298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016298", "evidence": [ { "database": "UniProtKB", "id": "Q9VPE9", "url": "https://www.uniprot.org/uniprotkb/Q9VPE9" } ], "pmid": "" }, { "name": "triacylglycerol lipase activity", "id": "GO:0004806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004806", "evidence": [ { "database": "UniProtKB", "id": "Q9VPE9", "url": "https://www.uniprot.org/uniprotkb/Q9VPE9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "Q9VPE9", "url": "https://www.uniprot.org/uniprotkb/Q9VPE9" } ], "pmid": "" }, { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "Q9VPE9", "url": "https://www.uniprot.org/uniprotkb/Q9VPE9" } ], "pmid": "" }, { "name": "cholesterol homeostasis", "id": "GO:0042632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042632", "evidence": [ { "database": "UniProtKB", "id": "Q9VPE9", "url": "https://www.uniprot.org/uniprotkb/Q9VPE9" } ], "pmid": "" }, { "name": "triglyceride homeostasis", "id": "GO:0070328", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070328", "evidence": [ { "database": "UniProtKB", "id": "Q9VPE9", "url": "https://www.uniprot.org/uniprotkb/Q9VPE9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "Q9VPE9", "url": "https://www.uniprot.org/uniprotkb/Q9VPE9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 270, "end_pos": 272, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPE9" }, { "id": "PF04083", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04083" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Partial AB-hydrolase lipase", "eco_id": "ECO_0000259", "start_pos": 34, "end_pos": 93, "start_aa": "Glu", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { 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Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VPF6", "url": "https://www.uniprot.org/uniprotkb/Q9VPF6" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VPF6", "url": "https://www.uniprot.org/uniprotkb/Q9VPF6" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPF6", "url": "https://www.uniprot.org/uniprotkb/Q9VPF6" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPF6", "url": "https://www.uniprot.org/uniprotkb/Q9VPF6" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VPF6", "url": "https://www.uniprot.org/uniprotkb/Q9VPF6" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VPF6", "url": "https://www.uniprot.org/uniprotkb/Q9VPF6" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VPF6", "url": "https://www.uniprot.org/uniprotkb/Q9VPF6" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPF6", "url": "https://www.uniprot.org/uniprotkb/Q9VPF6" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPF6", "url": "https://www.uniprot.org/uniprotkb/Q9VPF6" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VPF6", "url": "https://www.uniprot.org/uniprotkb/Q9VPF6" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VPF6", "url": "https://www.uniprot.org/uniprotkb/Q9VPF6" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] }, { "title": "Quantitative and site-specific chemoproteomic profiling of O-GlcNAcylation in Drosophila.", "journal": "Bioorganic & medicinal chemistry", "date": "2025-04-10", "authors": "Lei Cong, Chen Zihan, Hao Yi, Huang Wanping, Chu Tianyu, Xiao Kangming, Zhang Che, Zhou Wen, Li Chenjian, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9VPF6", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9VPF6" } ], "reference": [ { "type": "PubMed", "id": "40245499", "url": "https://glygen.org/publication/PubMed/40245499" } ] } ], "pathway": [ { "id": "dme:Dmel_CG5219", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG5219", "resource": "KEGG Pathway" }, { "id": "R-DME-5389840", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-5389840", "resource": "Reactome", "description": "Mitochondrial translation elongation" }, { "id": "R-DME-5419276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-5419276", "resource": 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}, "evidence": [ { "id": "Q9VPF6", "url": "https://omabrowser.org/oma/group/Q9VPF6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54PP3-1", "protein_name": "Ribosomal protein L15, mitochondrial", "gene_name": "mrpl15", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNFGNFCKSFSKITLSNNITGFRTIVSRPNEISLNNLRDNPGAVTKKVRVGRGIGSGRGKTSTRGHSGQKARAGHNIPRAFEGGQTQLFKKMRKYGFSNARFERVLTPINFNTLDRLIRENRINPNETITMKHLFDANCTGAIKHGIKLLSDGKQNFKHKINIELSDFSAPARETVEALGGVAKNVYYDRLGLRFLLKPHKFDFVPNRARVPLKYVSKYPDHVTGYMGAYSTKGEKFLKVQEEQEQEQKQ", "length": 251 }, "evidence": [ { "id": "Q9VPF6", "url": "https://omabrowser.org/oma/group/Q9VPF6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q6DGM3-1", "protein_name": "Large ribosomal subunit protein uL15m", "gene_name": "mrpl15", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSLIKKPGGKTIEVVKNLPRITLANLRPNPGAKTLEKRRGRGMHGGNRSGWGHKGERQRCNRPRLGFEGGQTPFYLVIPKYGYNANHSRQPQYPPLSLRRLQYLIDLGRIDPSQPIDLTQLVNGRGVEIQPQKRDYGVQLVDEGADIFCAKVNLEVQAASEKAIAAVERNGGVITTSYYDPRSLQILIKPVPFFMPGEPIPKRLFPGEDLLPYYTDANNRGYLADPDKIQTARMDLAKKYGYSIPDISKDTLFEMLVQRKNPRHIFFGLSPGWVVNMADKKILKPTDDKVLQYYGS", "length": 296 }, "evidence": [ { "id": "RGD:1304796", "url": "https://alliancegenome.org/gene/RGD:1304796#orthology", "database": "AGR" }, { "id": "MGI:1351639", "url": "https://alliancegenome.org/gene/MGI:1351639#orthology", "database": "AGR" }, { "id": "HGNC:14054", "url": "https://alliancegenome.org/gene/HGNC:14054#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040801-168", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040801-168#orthology", "database": "AGR" }, { "id": "FB:FBgn0036990", "url": "https://alliancegenome.org/gene/FB:FBgn0036990#orthology", "database": "AGR" }, { "id": "SGD:S000005228", "url": "https://alliancegenome.org/gene/SGD:S000005228#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9CPR5-1", "protein_name": "Large ribosomal subunit protein uL15m", "gene_name": "Mrpl15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGTARGCGTSLDLLRSLPRVSLANLKPSPNSRKRERRPRDRRRGRKCGRGHKGERQRGTRPRLGFEGGQTPFYIRIPKYGFNEGHSFRHQYQPLSLRRLQYLIDLGRVDPTQPIDLTQLVNGRGVTIQPLKRDYGVQLVEEGADTFQAKINIEVQLASELAIAAIEKNGGVVTTAFYDPRSLEILCKPIPFFLRGQPIPKRMLPPESLVPYYTDAKNRGYLADPAKFPEARLELAMKFGYVLPDITKDELFRMLSARKDPRQIFFGLAPGWVVNMADKKILKPTDENLLKYYSS", "length": 295 }, "evidence": [ { "id": "RGD:1304796", "url": "https://alliancegenome.org/gene/RGD:1304796#orthology", "database": "AGR" }, { "id": "MGI:1351639", "url": "https://alliancegenome.org/gene/MGI:1351639#orthology", "database": "AGR" }, { "id": "HGNC:14054", "url": "https://alliancegenome.org/gene/HGNC:14054#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040801-168", "url": 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"" }, { "id": "MONDO:0009478", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009478", "name": "dedicator of cytokinesis 8 deficiency", "description": "" }, { "id": "MONDO:0009478", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009478", "name": "AR hyperimmunoglobulin E syndrome", "description": "" }, { "id": "MONDO:0009478", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009478", "name": "AR-HIES", "description": "" }, { "id": "MONDO:0009478", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009478", "name": "DOCK8 deficiency", "description": "" }, { "id": "MONDO:0009478", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009478", "name": "HIES autosomal recessive", "description": "" }, { "id": "MONDO:0009478", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009478", "name": "autosomal recessive hyper IgE syndrome", "description": 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dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome", "description": "An autoimmune disease that is characterized by onset in infancy of refractory diarrhea, endocrinopathies, type 1 diabetes mellitus, and dermatitis that has_material_basis_in X-linked recessive mutation in the forkhead box P3 (FOXP3) gene on chromosome Xp11." }, "synonyms": [ { "id": "DOID:0090110", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090110", "name": "immunodeficiency, polyendocrinopathy, and enteropathy, X-linked", "description": "" }, { "id": "DOID:0090110", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090110", "name": "immunodysregulation, polyendocrinopathy, and enteropathy, X-Linked", "description": "" }, { "id": "DOID:0090110", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090110", "name": "X-linked autoimmunity-allergic dysregulation syndrome", "description": "" }, { "id": "DOID:0090110", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090110", "name": "Autoimmune enteropathy type 1", "description": "" }, { "id": "DOID:0090110", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090110", "name": "DMSD", "description": "" }, { "id": "DOID:0090110", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090110", "name": "IDDM-secretory diarrhea syndrome", "description": "" }, { "id": "DOID:0090110", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090110", "name": "IPEX", "description": "" }, { "id": "DOID:0090110", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090110", "name": "diabetes mellitus, congenital insulin-dependent, with fatal secretory diarrhea", "description": "" }, { "id": "DOID:0090110", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090110", "name": "XLAAD", "description": "" }, { "id": "DOID:0090110", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090110", "name": "XPID", "description": "" }, { "id": "DOID:0090110", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090110", "name": "autoimmunity-immunodeficiency syndrome, X-linked", "description": "" }, { "id": "DOID:0090110", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090110", "name": "diarrhea, polyendocrinopathy, fatal infection syndrome, X-linked", "description": "" }, { "id": "MONDO:0010580", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010580", "name": "immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome", "description": "Immunodysregulation - polyendocrinopathy - enteropathy - X-linked (IPEX) syndrome is a severe congenital systemic autoimmune disease characterized by refractory diarrhea, endocrinopathies, cutaneous involvement, and infections." }, { "id": "MONDO:0010580", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010580", "name": "DMSD", "description": "" }, { "id": "MONDO:0010580", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010580", "name": "IDDM-secretory diarrhea syndrome", "description": "" }, { "id": "MONDO:0010580", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010580", "name": "IDDM-secretory diarrhoea syndrome", "description": "" }, { "id": "MONDO:0010580", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010580", "name": "IPEX", "description": "" }, { "id": "MONDO:0010580", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010580", "name": "X linked polyendocrinopathy", "description": "" }, { "id": "MONDO:0010580", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010580", "name": "X-linked autoimmunity-allergic dysregulation syndrome", "description": "" }, { "id": "MONDO:0010580", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010580", "name": "XLAAD", "description": "" }, { "id": "MONDO:0010580", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010580", "name": "XPID", "description": "" }, { "id": "MONDO:0010580", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010580", "name": "autoimmune enteropathy type 1", "description": "" }, { "id": "MONDO:0010580", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010580", "name": "autoimmunity-immunodeficiency syndrome, X-linked", "description": "" }, { "id": "MONDO:0010580", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010580", "name": "diabetes mellitus, congenital insulin-dependent, with fatal secretory diarrhea", "description": "" }, { "id": "MONDO:0010580", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010580", "name": "diabetes mellitus, congenital insulin-dependent, with fatal secretory diarrhoea", "description": "" }, { "id": "MONDO:0010580", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010580", "name": "diarrhea, polyendocrinopathy, fatal infection syndrome, X-linked", "description": "" }, { "id": "MONDO:0010580", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010580", "name": "immune dysfunction and diarrhea syndrome", "description": "" }, { "id": "MONDO:0010580", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010580", "name": "immune dysfunction and diarrhoea syndrome", "description": "" }, { "id": "MONDO:0010580", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010580", "name": "immune dysregulation, polyendocrinopathy, and enteropathy X-linked syndrome", "description": "" }, { "id": "MONDO:0010580", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010580", "name": "immunodysregulation, polyendocrinopathy, and enteropathy, X-linked", "description": "" }, { "id": "MONDO:0010580", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010580", "name": "immunodysregulation, polyendocrinopathy, and enteropathy, X-linked, X-linked recessive", "description": "" }, { "id": "MONDO:0010580", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010580", "name": "IDDM secretory diarrhea syndrome", "description": "" }, { "id": "MONDO:0010580", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010580", "name": "IDDM secretory diarrhoea syndrome", "description": "" }, { "id": "MONDO:0010580", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010580", "name": "IMMUNODYSREGULATION, polyendocrinopathy, and enteropathy, X-linked", "description": "" }, { "id": "MONDO:0010580", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010580", "name": "IPEX syndrome", "description": "" }, { "id": "MONDO:0010580", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010580", "name": "Iddm-secretory diarrhoea syndrome", "description": "" }, { "id": "MONDO:0010580", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010580", "name": "Immunodysregulation, polyendocrinopathy and enteropathy X-linked", "description": "" }, { "id": "MONDO:0010580", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010580", "name": "autoimmunity-immunodeficiency syndrome X-linked", "description": "" }, { "id": "MONDO:0010580", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010580", "name": "enteropathy, autoimmune, with hemolytic Anaemia and polyendocrinopathy", "description": "" }, { "id": "MONDO:0010580", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010580", "name": "polyendocrinopathy, immune dysfunction and diarrhea X-linked", "description": "" }, { "id": "MONDO:0010580", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010580", "name": "polyendocrinopathy, immune dysfunction and diarrhoea X-linked", "description": "" }, { "id": "MIM:304790", "resource": "MIM", "url": "https://www.omim.org/entry/304790", "name": "Immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome", "description": "Immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome" } ], "unlinked_id_list": [], "evidence": [ { "id": "0090110", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090110" } ] }, { "disease_id": "DOID:104", "recommended_name": { "id": "DOID:104", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:104", "name": "bacterial infectious disease", "description": "A disease by infectious agent that results_in infection, has_material_basis_in Bacteria." }, "synonyms": [], "unlinked_id_list": [ "DOID:2149", "DOID:0050339", "DOID:11104", "DOID:10458" ], "evidence": [ { "id": "104", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:104" } ] }, { "disease_id": "DOID:10534", "recommended_name": { "id": "DOID:10534", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach." }, "synonyms": [ { "id": "DOID:10534", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10534", "name": "gastric cancer", "description": "" }, { "id": "DOID:10534", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10534", "name": "gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer", "description": "A primary or metastatic malignant neoplasm involving the stomach." }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "Ca lesser curvature - stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "GC", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "cancer of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer risk after h. pylori infection", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer, somatic", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric tumor", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric tumour", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant stomach neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of body of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of greater curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of body of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of greater curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "stomach cancer", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "Ca body - stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "ca greater curvature of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of body of stomach", "description": "" }, { "id": "MIM:613659", "resource": "MIM", "url": "https://www.omim.org/entry/613659", "name": "Gastric cancer", "description": "Gastric cancer" } ], "unlinked_id_list": [], "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ] }, { "disease_id": "DOID:2043", "recommended_name": { "id": "DOID:2043", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2043", "name": "hepatitis B", "description": "A viral hepatitis that results_in inflammation located_in liver, has_material_basis_in Hepatitis B virus (Orthohepadnavirus hominoidei), which is transmitted_by sexual contact, blood transfusions, or fomites like needles or syringes. The infection has_symptom fever, fatigue, loss of appetite, nausea, vomiting, abdominal pain, clay-colored bowel movements, joint pain, and jaundice." }, "synonyms": [ { "id": "DOID:2043", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2043", "name": "chronic hepatitis B", "description": "" }, { "id": "DOID:2043", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2043", "name": "hepatitis B infection", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "2043", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2043" } ] }, { "disease_id": "DOID:2223", "recommended_name": { "id": "DOID:2223", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2223", "name": "platelet storage pool deficiency", "description": "" }, "synonyms": [ { "id": "DOID:2223", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2223", "name": "Dense body defect", "description": "" }, { "id": "DOID:2223", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2223", "name": "Platelet dense granule deficiency", "description": "" }, { "id": "DOID:2223", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2223", "name": "Platelet storage pool defect", "description": "" }, { "id": "MONDO:0008495", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008495", "name": "platelet storage pool deficiency", "description": "Platelet storage pool deficiency refers to a group of conditions that are caused by problems with the platelet granules. Platelet granules are tiny storage sacs found within the platelets which release various substances to help stop bleeding. Platelet storage pool deficiencies occur when platelet granules are absent, reduced in number, or unable to empty their contents into the bloodstream. The signs and symptoms include frequent nosebleeds; abnormally heavy or prolonged menstruation ; easy bruising; recurrent anemia ; and abnormal bleeding after surgery, dental work or childbirth. Platelet storage pool deficiencies may be genetic or acquired (non-genetic). They can also be part of an inherited genetic syndrome such as Hermansky-Pudlak syndrome, Chediak-Higashi syndrome, thrombocytopenia-absent radius (TAR) syndrome, and Wiskott-Aldrich syndrome. Treatment is symptomatic." }, { "id": "MONDO:0008495", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008495", "name": "alpha dense granule deficiency", "description": "" }, { "id": "MONDO:0008495", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008495", "name": "combined alpha-delta platelet storage pool deficiency", "description": "" }, { "id": "MONDO:0008495", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008495", "name": "platelet storage pool diseases", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "2223", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2223" } ] }, { "disease_id": "DOID:3310", "recommended_name": { "id": "DOID:3310", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3310", "name": "atopic dermatitis", "description": "An allergic contact dermatitis that is a chronically relapsing inflammatory allergic response located_in the skin that causes itching and flaking." }, "synonyms": [ { "id": "DOID:3310", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3310", "name": "Atopic neurodermatitis", "description": "" }, { "id": "DOID:3310", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3310", "name": "Besnier's prurigo", "description": "" }, { "id": "DOID:3310", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3310", "name": "allergic dermatitis", "description": "" }, { "id": "DOID:3310", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3310", "name": "atopic eczema", "description": "" }, { "id": "MONDO:0004980", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0004980", "name": "atopic eczema", "description": "A common chronic pruritic inflammatory skin disease with a strong genetic component. Onset typically occurs during the first 2 years of life." }, { "id": "MONDO:0004980", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0004980", "name": "ATOD", "description": "" }, { "id": "MONDO:0004980", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0004980", "name": "allergic form of dermatitis", "description": "" }, { "id": "MONDO:0004980", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0004980", "name": "atopic dermatitis", "description": "" }, { "id": "MONDO:0004980", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0004980", "name": "atopic eczema", "description": "" }, { "id": "MONDO:0004980", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0004980", "name": "dermatitis, atopic", "description": "" }, { "id": "MONDO:0004980", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0004980", "name": "eczema", "description": "" }, { "id": "MONDO:0004980", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0004980", "name": "eczema, atopic", "description": "" }, { "id": "MONDO:0004980", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0004980", "name": "eczematous dermatitis", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "3310", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3310" } ] }, { "disease_id": "DOID:934", "recommended_name": { "id": "DOID:934", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:934", "name": "viral infectious disease", "description": "A disease by infectious agent that results in infection, has_material_basis_in Viruses." }, "synonyms": [ { "id": "DOID:934", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:934", "name": "Viral Infection", "description": "" }, { "id": "DOID:934", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:934", "name": "Viral disease", "description": "" }, { "id": "DOID:934", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:934", "name": "virus infection", "description": "" } ], "unlinked_id_list": [ "DOID:8672" ], "evidence": [ { "id": "934", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:934" } ] }, { "disease_id": "DOID:9744", "recommended_name": { "id": "DOID:9744", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9744", "name": "type 1 diabetes mellitus", "description": "A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production." }, "synonyms": [ { "id": "DOID:9744", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9744", "name": "IDDM", "description": "" }, { "id": "DOID:9744", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9744", "name": "insulin-dependent diabetes mellitus", "description": "" }, { "id": "DOID:9744", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9744", "name": "type I diabetes mellitus", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "type 1 diabetes mellitus", "description": "A chronic condition characterized by minimal or absent production of insulin by the pancreas." }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "IDDM", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "T1D", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "T1DM", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "diabetes mellitis type 1", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "diabetes mellitis type I", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "immune mediated diabetes", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "insulin dependent diabetes", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "juvenile diabetes", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "type 1 diabetes", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "type I diabetes", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "type I diabetes mellitus", "description": "" }, { "id": "MIM:222100", "resource": "MIM", "url": "https://www.omim.org/entry/222100", "name": "Type 1 diabetes mellitus", "description": "Type 1 diabetes mellitus" } ], "unlinked_id_list": [], "evidence": [ { "id": "9744", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9744" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VPI9", "url": "https://www.uniprot.org/uniprotkb/Q9VPI9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Zir", "url": "https://www.uniprot.org/uniprotkb/Q9VPI9", "locus": { "chromosome": "2L", "start_pos": 102086, "end_pos": 94739, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0031216", "url": "https://www.ensemblgenomes.org/id/FBgn0031216" } ] } } ], "crossref": [ { "id": "FB:FBgn0031216", "url": "https://alliancegenome.org/gene/FB:FBgn0031216", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0031216", "url": "https://bgee.org/?page=gene&gene_id=FBgn0031216", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08696", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08696", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11695", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11695", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0031216", "url": "https://flybase.org/reports/FBgn0031216", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "33165", "url": "https://www.ncbi.nlm.nih.gov/gene/33165", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VPI9", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VPI9*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR021816", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021816", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026791", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026791", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027007", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027007", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027357", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027357", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037808", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037808", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043161", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043161", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043162", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043162", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046769", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046769", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046773", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046773", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG11376", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG11376", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FPHQFND", "url": "https://omabrowser.org/oma/group/FPHQFND/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VPI9", "url": "https://www.orthodb.org/?gene=Q9VPI9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23317", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23317", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23317:SF76", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23317:SF76", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06920", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06920", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11878", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11878", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14429", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14429", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20421", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20421", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20422", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20422", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF28208", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28208", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-9013148", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9013148", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-9013409", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9013409", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-983231", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-983231", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_608489", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608489", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VPI9", "url": "https://www.uniprot.org/uniprotkb/Q9VPI9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VPI9-1", "url": "https://www.uniprot.org/uniprotkb/Q9VPI9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSAQRSFVQKVSKQSAADVRKNVSGCHLSKAMDPSLCGSSISPTEPLDYEEFLSQHMNIINRDPLKHILDFPQGDVTVKIIPRKIRTVDHVVPNENLSDLPHHVQECVNCYTRPWKVVEYAQRHLSSSCYIRERIDRGTISPSAYQQEFEIDKDFSSFEEAFAYKSESCTPSSRQSIASLASVSSCTDTLTPRGSWASFDLRRSVNDPLIPNLLDNVPPEHIDQSNEARRQQDRQMALFSLYPESEAEENIERRLLAEIPVEHMGHRIQVNCLQLRLELEVEPIFASMAIYDAKERQKISENFYFDMNADSLKRMLSSHVQCADISTQSHSAIFEISYPSNDLFLVIRLEKVLQGDINNSVEPYLKEDKDKYREKVKSNAVDYCERLGKYRMPFAWTGIYLTNVFNGDNFESKDAGAAERDSFGNACGSSLGTAPSSNSLDRKSSTSSFDQLRRKANDMSGTLTRRGSLERKEKHRSWSPDDFANVVENFRPITITVPSFFKQEADKMKDEDLYKILPELKRPSSVMKKYKCIPGSIKLEISPCVEEAKNALTPELAPINPQSADNVRPVKEILEFPQSAIYNPHYSYRNLLFVSPKELNFSSRAGSARNIAVRVQLMAGETPKDAVNAIYGKSSCPKFSTEAFTAVNYHNKCPSFYDEIKIALPASIKQHHHLLFTIYHVSCQKKPQDLQPSVETPIGYTWLPLLEDGKLKFGEFNLPVMVESPPENYSFIPPNVHLPGIKWLDNHRAVFSINVEAVTAIHTLDSFLDRFFLICEYLDTRNIPSHIGENNIETELKKCLLDIEYANREPLVRHLPLVLDKLIELLVVTHKVGGQAMSLGSTVFEVLCLVSSLLSILNDDQYDQYGRQSLLSTYVHFQCKIPHPFQSKQRLTCSRSTTEDLQLSESYTIYDNVLASGRSLDRKELSIDVLHSMAARDVQVRLLHEELALHWVVASGKAADLAMSNSWFLFELIVKSMIEHLHCSNTLNGPRKHRFPHQFNDDLSTLVHLVTTKVVGYHSNEPKLAQSLNASLGFFIFDILSIMDRGFVFGLIKTYTKVLISKNASIPDLMNYKIDFLRIVCSHEHFVALNLPFGTSYTMVTAPCSPTPSTTSSNSQTSCGSLERALHADLSQEFLQQHFLVGLVLSDLAAVMEVPNPQLHGKAIRCIRNLMTSHDLDARYSETDARARVAALYIPLLSIVMDCIPQLHQHGLEQDRLQQIGQLEDYQGPHQTITASTINPEVAFAISGSRPYSYLNEQVKNKLPLSSENTRHLLVCFLWVLKNLERNVLYRWLMDLSPHRVHQMLQGVNVCLKTFEYTGQKNVATLKRTNTQSFRKTGSTDVKEKLEECIRGTNSARYDLINRRKDRNSTEKFRWRKDQMPYRSQYADAVGKSEHELELSHFIEGSLATEVALVLLDTLEIIVHAAANLYHNLLGTVLKVLLHSLSRNQSVLALQNLFASQRALIFKFPNLLFDDETDICADLCLILLKHCGSLLPGIRSQAAASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSSVFSEQSLRRALKTVLVYAESDSDLQDTSFPEQVQDLLFNLHMILSDTVKMKEYQEDPEMLLDLMNRIAKGYQNNPDLRLTWLENMAKKHRERANHTEAAMCYVHAASLVSEYLSMLESQKHLPVGAVSFQRISPNTLMESAVSDDVLSPGEDGICLGNHFTETGLKALLEEASNSFQVAGMYEAMNEVYKILIPICEANRDFQKLSKVHGKLQEAFNRISQLQGKRVFGTYFRVGFYGGKFGDLDQQEFIYKEPTLTKLPEIFSRLQNFYTERFGPDSVHIIKDSNTVDINSLDPDKAYIQITYVEPYFETYEMRHRETYFERNFNIKRFIYATPFTKNGKAHGELNEQCKRKTILTTANHFPYVKTRIMVISRQQIVLEPIEVAIEDIQKKTLELAAATNQEPADPKILQMVLQGCIGTTVNQGPMEMASVFLSNLSDGTTVPTKHQNKLRLCFREFSKRCADALKKNRNLILSDQKDYQRELERNNDRFIERLTPFITLTSVQNHGVVKANAYNNKSTPLKW", "length": 2064, "header": "tr|Q9VPI9-1|Q9VPI9_DROME Isoform 1 of Zizimin-related OS=Drosophila melanogaster OX=7227 GN=Zir PE=3 SV=2 CANONICAL=Q9VPI9-1" }, "isoforms": [ { "isoform_ac": "Q9VPI9-1", "url": "https://www.uniprot.org/uniprotkb/Q9VPI9/entry#Q9VPI9-1", "sequence": { "sequence": "MSSAQRSFVQKVSKQSAADVRKNVSGCHLSKAMDPSLCGSSISPTEPLDYEEFLSQHMNIINRDPLKHILDFPQGDVTVKIIPRKIRTVDHVVPNENLSDLPHHVQECVNCYTRPWKVVEYAQRHLSSSCYIRERIDRGTISPSAYQQEFEIDKDFSSFEEAFAYKSESCTPSSRQSIASLASVSSCTDTLTPRGSWASFDLRRSVNDPLIPNLLDNVPPEHIDQSNEARRQQDRQMALFSLYPESEAEENIERRLLAEIPVEHMGHRIQVNCLQLRLELEVEPIFASMAIYDAKERQKISENFYFDMNADSLKRMLSSHVQCADISTQSHSAIFEISYPSNDLFLVIRLEKVLQGDINNSVEPYLKEDKDKYREKVKSNAVDYCERLGKYRMPFAWTGIYLTNVFNGDNFESKDAGAAERDSFGNACGSSLGTAPSSNSLDRKSSTSSFDQLRRKANDMSGTLTRRGSLERKEKHRSWSPDDFANVVENFRPITITVPSFFKQEADKMKDEDLYKILPELKRPSSVMKKYKCIPGSIKLEISPCVEEAKNALTPELAPINPQSADNVRPVKEILEFPQSAIYNPHYSYRNLLFVSPKELNFSSRAGSARNIAVRVQLMAGETPKDAVNAIYGKSSCPKFSTEAFTAVNYHNKCPSFYDEIKIALPASIKQHHHLLFTIYHVSCQKKPQDLQPSVETPIGYTWLPLLEDGKLKFGEFNLPVMVESPPENYSFIPPNVHLPGIKWLDNHRAVFSINVEAVTAIHTLDSFLDRFFLICEYLDTRNIPSHIGENNIETELKKCLLDIEYANREPLVRHLPLVLDKLIELLVVTHKVGGQAMSLGSTVFEVLCLVSSLLSILNDDQYDQYGRQSLLSTYVHFQCKIPHPFQSKQRLTCSRSTTEDLQLSESYTIYDNVLASGRSLDRKELSIDVLHSMAARDVQVRLLHEELALHWVVASGKAADLAMSNSWFLFELIVKSMIEHLHCSNTLNGPRKHRFPHQFNDDLSTLVHLVTTKVVGYHSNEPKLAQSLNASLGFFIFDILSIMDRGFVFGLIKTYTKVLISKNASIPDLMNYKIDFLRIVCSHEHFVALNLPFGTSYTMVTAPCSPTPSTTSSNSQTSCGSLERALHADLSQEFLQQHFLVGLVLSDLAAVMEVPNPQLHGKAIRCIRNLMTSHDLDARYSETDARARVAALYIPLLSIVMDCIPQLHQHGLEQDRLQQIGQLEDYQGPHQTITASTINPEVAFAISGSRPYSYLNEQVKNKLPLSSENTRHLLVCFLWVLKNLERNVLYRWLMDLSPHRVHQMLQGVNVCLKTFEYTGQKNVATLKRTNTQSFRKTGSTDVKEKLEECIRGTNSARYDLINRRKDRNSTEKFRWRKDQMPYRSQYADAVGKSEHELELSHFIEGSLATEVALVLLDTLEIIVHAAANLYHNLLGTVLKVLLHSLSRNQSVLALQNLFASQRALIFKFPNLLFDDETDICADLCLILLKHCGSLLPGIRSQAAASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSSVFSEQSLRRALKTVLVYAESDSDLQDTSFPEQVQDLLFNLHMILSDTVKMKEYQEDPEMLLDLMNRIAKGYQNNPDLRLTWLENMAKKHRERANHTEAAMCYVHAASLVSEYLSMLESQKHLPVGAVSFQRISPNTLMESAVSDDVLSPGEDGICLGNHFTETGLKALLEEASNSFQVAGMYEAMNEVYKILIPICEANRDFQKLSKVHGKLQEAFNRISQLQGKRVFGTYFRVGFYGGKFGDLDQQEFIYKEPTLTKLPEIFSRLQNFYTERFGPDSVHIIKDSNTVDINSLDPDKAYIQITYVEPYFETYEMRHRETYFERNFNIKRFIYATPFTKNGKAHGELNEQCKRKTILTTANHFPYVKTRIMVISRQQIVLEPIEVAIEDIQKKTLELAAATNQEPADPKILQMVLQGCIGTTVNQGPMEMASVFLSNLSDGTTVPTKHQNKLRLCFREFSKRCADALKKNRNLILSDQKDYQRELERNNDRFIERLTPFITLTSVQNHGVVKANAYNNKSTPLKW", "length": 2064, "header": "tr|Q9VPI9-1|Q9VPI9_DROME Isoform 1 of Zizimin-related OS=Drosophila melanogaster OX=7227 GN=Zir PE=3 SV=2 CANONICAL=Q9VPI9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1108, "start_aa": "Thr", "end_pos": 1108, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1108", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VPI9", "url": "https://www.uniprot.org/uniprotkb/Q9VPI9" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VPI9", "url": "https://www.uniprot.org/uniprotkb/Q9VPI9" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPI9", "url": "https://www.uniprot.org/uniprotkb/Q9VPI9" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPI9", "url": "https://www.uniprot.org/uniprotkb/Q9VPI9" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VPI9", "url": "https://www.uniprot.org/uniprotkb/Q9VPI9" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VPI9", "url": "https://www.uniprot.org/uniprotkb/Q9VPI9" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VPI9", "url": "https://www.uniprot.org/uniprotkb/Q9VPI9" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPI9", "url": "https://www.uniprot.org/uniprotkb/Q9VPI9" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPI9", "url": "https://www.uniprot.org/uniprotkb/Q9VPI9" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VPI9", "url": "https://www.uniprot.org/uniprotkb/Q9VPI9" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VPI9", "url": "https://www.uniprot.org/uniprotkb/Q9VPI9" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG11376", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG11376", "resource": "KEGG Pathway" }, { "id": "R-DME-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-DME-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" }, { "id": "R-DME-9013409", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9013409", "resource": "Reactome", "description": "RHOJ GTPase cycle" }, { "id": "R-DME-983231", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-983231", "resource": "Reactome", "description": "Factors involved in megakaryocyte development and platelet production" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2KAH4-1", "protein_name": "Dedicator of cytokinesis 6", "gene_name": "Dock6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAASERRAFAHKINRTVAAEVRKQVSRERSGSPHSSRRSSSSLGVPLTEVIEPLDFEDVLLSRPPEVEPGPLRDMIEFPADDLELLKQPRECRTTESGVPEDGKLDAQVRAAVEMYSEDWVIVRRRYQHLSTAYSPITTETQRERQKGLTCQVFEQDTPGDERTGPEDVDDSQHCSGSPEDTPRSSGASGVFSLRNLAADSLLPTLLERAAPEDVDRRNEALRRQHRAPALLTLYPAPDEDEAVERCSHPEPPREHFGQRILVKCLSLKFEIEIEPIFGTLALYDVREKKKISENFYFDLNSDSVKGLLRAHGTHPAISTLARSAIFSVTYPSPDIFLVVKLEKVLQQGDISECCEPYMVMKEADTVKNKEKLEKLRLAAEQFCTRLGRYRMPFAWTAVHLANIVSSVGPQDRDSDSEGERRPTWAERRRRGPQDRSYSGDDACSFSSFRPATLTVTNFFKQEAERLSDEDLFKFLADMRRPSSLLRRLRPVTAQLKIDISPAPENLHFCLSPELLHVKPYPDPRGRPTKEILEFPAREVYAPHTCYRNLLFVYPHSLNFSSRQGSVRNLAVRIQYMAGEDQSQALPVIFGKSSCSEFTREAFTPVVYHNKSPEFYEEFKLRLPACVTENHHLFFTFYHVSCQPRPGTALETPVGFTWIPLLQHGRLRTGPFCLPVSVDQPPPSYSVLTPDVALPGMRWVDGHKGVFSVELTAVSSVHPQDPHLDKFFTLVHVLEEGIFPFRLKETVLSEGTMEQELRASLAALRLASPEPLVAFSHHVLDKLVRLVVRPPVICGQMVNLGRGAFEAMAHVASLVHRNLEAVQDSRGHCPLLAAYVHYAFRLPGGDLGLPGEVPPATVQAATLARGSGRPASLYLARSKSISSSNPDLAVVPGSVDDEVSRILASKGVDRSHSWVNSAYAPGGSKAVLRRVPPYCGADPRQLLHEELALQWVVSGSAVRELVLQHAWFFFQLMVKSMELHLLLGQRLDTPRKLRFPGRFLDDIAALVASVGLEVITRVHKDMELAERLNASLAFFLSDLLSIADRGYIFSLVRAHYKQVATRLQSAPNPAALLTLRMDFTRILCSHEHYVTLNLPCCPLSPPASPSPSVSSTTSQSSTFSSQAPDPKVISMFELSGPFRQQHFLSGLLLTELALALDPEAEGASLLHKKAITAVHNLLCSHDVDSRYTDATVKAKVAELYLPLLSLARDTLPRLHGFAEGSGQRSRLASMLDSDTEGEGDIGGTINPSVAMAIAGGPLAPGSRTSISQGPSTAARSGCPLSAESSRTLLVCVLWVLKNAEPALLQRWAADLALPQLGRLLDLLYLCLAAFEYKGKKAFERINSLTFKKSLDMKARLEEAILGTIGARQEMVRRSRERSPFGNQENVRWRKSVTHWRQTSDRVDKTKDEVEHEALVDGNLATEASLVVLDMLEIIVQTVMLSEARESILGAVLKVVLYSLGSAQSALFLQHGLATQRALVSKFPELLFEEDTELCADLCLRLLRHCGSRISTIRTHASASLYLLMRQNFEIGHNFARVKMLVTMSLSSLVGTTQNFSEEHLRRSLKTILTYAEEDLGLRDSTFAEQVQDLMFNLHMILTDTVKMKEHQEDPEMLMDLMYRIARGYQGSPDLRLTWLQNMASKHAELGNHAEAAQCMVHAAALVAEYLALLEDSRHLPVGCVSFQNVSSNVLEESAISDDILSPDEEGFCSGKNFTDLGLVGLLEQAAAYFTMGGLYEAVNEVYKNLIPILEAHRDYKKLAAVHGKLQEAFTKIMHQSSGWERVFGTYFRVGFYGARFGDLDEQEFVYKEPSITKLAEISHRLEEFYTERFGDDVVEIIKDSNPVDKLKLDPQKAYIQITYVEPHFDTYELKDRVTYFDRNYGLRAFLFCTPFTPDGRAHGELAEQHKRKTLLSTEHAFPYIKTRIRVCHREETVLTPVEVAIEDMQKKTRELAFATEQDPPDAKMLQMVLQGSVGPTVNQGPLEVAQVFLSEIPEDPKLFRHHNKLRLCFKDFCKKCEDALRKNKALIGPDQKEYHRELERHYSRLREALQPLLTQRLPQLLAPSSTSLRNSINRSSFRKTDL", "length": 2082 }, "evidence": [ { "id": "HGNC:19189", "url": "https://alliancegenome.org/gene/HGNC:19189#orthology", "database": "AGR" }, { "id": "MGI:1914789", "url": "https://alliancegenome.org/gene/MGI:1914789#orthology", "database": "AGR" }, { "id": "RGD:1306517", "url": "https://alliancegenome.org/gene/RGD:1306517#orthology", "database": "AGR" }, { "id": "FB:FBgn0031216", "url": "https://alliancegenome.org/gene/FB:FBgn0031216#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A829-1", "protein_name": "Dedicator of cytokinesis 8", "gene_name": "Dock8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHARQALLPRAEIFFFFFNSRYSSSEIRKQFTLPPNLGQYHRHSLSTSGFPSLQLPQLYEPVEPVDFEGLVMTHLNSLDAELAQELGDLTDDDLHVAFTPKECRTLQHSLPEEGVELDPHVRDCVQTYIREWLIVNRKNQGSPEFCSFRKTGSRRDFHKTLQKQTFESETLECSEPATQTGPRHRFNVLCDVSGKGPITSCDFDLRSLQPDERLENLLQLSAEDFEKEKEEARKTNRTAELFALYPSVDEEDAVEIRPVPECPKEHLGNRILVKVLTLKFEIEIEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVDPSSQARSAVFSVTYPSSDIYLVVKIEKVLQQGEIADCAEPYMIIKESDGGKSKEKVEKLKLQAESFCQRLGKYRMPFAWAPISLASFFNVSTLERESTDLEPGAGRNSVGERRSLSQSRRPSERTLSFEENGVGSNFKTTTLATNIFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIPGSLRLEIAPAPDVMNCCLTPEMLPVKPFPENRTRPHKEILEFPIREVYVPHTVYRNLLYVYPQRLNFANKLASARNITIKIQFMCGEDPSNAMPVIFGKSSGPEFLQEVYTAITYHNKSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQQKQGASGESLLGYSWLPILLNERLQTGSYCLPVALEKLPPNYSIHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDNHLEKFFTLCHSLESQVTFPIRVLDQKITENTLEHELKLSIICLNSSRLEPLVLFLHLVLDKLFQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLRKDQHGRNCLLASYVHYVFRLPELHRDAPKSGGPTAVVPDPRYHTYGRTSAAAVSSKLMQARVMSSSNPDLAGTHCAADEEVKNIMSSKIADRNCSRMSYYCSGNSDVPGSTAAPRPVSKKHFHEELALQMVVSTGLVRETVFKYAWFFFELLVKSMAQYVHNLDKRDSFRRTRFSDRFKDDITTIVNVVTSEIAALLVKPQKESEQAEKINISLAFFLYDLLSIMDRGFVFNLIKHYCTQLSAKLNTLPTLISMRLEFLRILCSHEHYLNLNLLFMNPDTAPASPCPSISSQNSSSCSSFQDQKIASMFDLTPEYRQQHFLTGLLFTELAVALDAEGDGISRVQRKAVSAIHSLLSSHDLDPRCLKPEVKVKIAALYLPLVGIILDALPQLYDFTDARSGRSRASGSYEEQDVANGINQNVALAIAGNHFNLKTSGAMLSSLPYKQYNMLNADTTRHLMVCFLWIMKNADQSLIRKWIADLPSMQLNRILDLLFICVSCFEYKGKQSSDKVSNQVLQKSRDVKAKLEEALLRGEGARGEMMRRRIPGTDRFPGLNENLRWRKEQTQWRQANEKLDKTKAELDQEALISGNLATEANLIILDMQENIIQASSSLDCKDSLLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKFGDLLFEEEMEQCADLCQRVLHHCSSSMDVTRSQACATLYLLMRFSFGATSNFARVKMQVTMALASLVGKAPDFNEEHLRKSLRTILAYSEEDTAMRATLFPTQVEELLCNLNSILYDTVKMREFQEDPEMLMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKRKCFTEAAMCLVHAAALVAEYLSMLEDHSYLPVGSVSFQNISSNVLEESAVSDDTLSPDEDGVCSGRYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHRDFRKLTSTHDKLQKAFDNIINKDHKRMFGTYFRVGFYGSKFGDLDEQEFVYKEPAITKLPEISHRLEGFYGQCFGAEFVEVIKDSTPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRFMYTTPFTLEGRPRGELHEQHRRNTVLTTMHAFPYIKTRIRVSQKEEFVLTPIEVAIEDMKKKTLQLAVATHQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHNKLRLCFKEFIMRCGEAVEKNRRLITAEQREYQQELKKNYNRLKDSLRPMIERKIPELYKPIFRVDSQKRDSFHRSSFRKCETQLSQGS", "length": 2102 }, "evidence": [ { "id": "HGNC:19191", "url": "https://alliancegenome.org/gene/HGNC:19191#orthology", "database": "AGR" }, { "id": "MGI:1921396", "url": "https://alliancegenome.org/gene/MGI:1921396#orthology", "database": "AGR" }, { "id": "RGD:1561588", "url": "https://alliancegenome.org/gene/RGD:1561588#orthology", "database": "AGR" }, { "id": "FB:FBgn0031216", "url": "https://alliancegenome.org/gene/FB:FBgn0031216#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ACL2-1", "protein_name": "Dedicator of cytokinesis 7", "gene_name": "Dock7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAERRAFAQKISRTVAAEVRKQISGQYSGSPQLLKNLNIVGNISHHTTVPLTEAVDPVDLEDYLITHPLAVDSGPLRDLVDFPPDDIEVVYSPRDCRTLVSAVPEESEMDPHVRDCIRSYTEDWAIVVRKYHKLGTGFNPNTLDKQKERQKGLPRQVFESDEAPDGNSYPDEQDDLKRRSMSIDDTPRGSWACSIFDLKNSLPDALLPNLLDRTPNEEIDHQNDDQRKSNRHKELFALHPSPDEEEPIERLSVPDVPKEHFGQRLLVKCLSLKFEIEIEPIFASLALYDVKEKKKISENFYFDLNSEQMKGLLRPHVPPAAITTLARSAIFSITYPSQDVFLVIKLEKVLQQGDIGECAEPYMIFKEADATKNKEKLEKLKSQADQFCQRLGKYRMPFAWTAIHLMNIVSSAGSLERDSTEVEISTGERKGSWSERRNSSLVGRRSLERTASGDDACNLTSFRPATLTVANFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPHYCLTPELLQVKLYPDSRVRPTREILEFPARDVYVPNTTYRNLLYIYPQSLNFANRQGSARNITVKVQFMYGEDPSNAMPVIFGKSSCSEFSKEAYTAVVYHNRSPDFHEEVKVKLPATLTDHHHLLFTFYHVSCQQKQNTPLETPVGYTWIPMLQNGRLKTGQFCLPVSLEKPPQAYSVLSPEVPLPGMKWVDNHKGVFNVEVVAVSSIHTQDPYLDKFFALVNALDEHMFPVRIGDMRIMENNLESELKSSISALNSSQLEPVVRFLHLLLDKLILLVVRPPVIAGQIVNLGQASFEAMASIINRLHKNLEGNHDQHGRNNLLASYIYYVFRLPNTYPNSPSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIIGSKGLDRSNSWVNTGPKAAPWGSNPSPSAESTQAVDRSCNRMSSHTETSSFLQTLTGRLPTKKLFHEELALQWVVCSGSVRESALQQAWFFFELMVKSMVHHLYFNDKLDAPRKSRFPERFMDDIAALVSTIAGDVVSRFQKDTEMVERLNTSLAFFLNDLLSVMDRGFVFTLIKSCYKQVSAKLYSLPNPSVLVSLRLDFLRIICSHEHYVTLNLPCSLLTPPASPSPSVSSATSQSSGFSTNVQDQKIANMFELSLPFRQQHYLAGLVLTELALILDPDAEGLFGLHKKVINMVHNLLSSHDSDPRYSDPQIKARVAMLYLPLIGIIMETVPQLYDFTETHNQRGRPICIAPDDYDSESGSMISQTVAMAIAGTSVPQLTRPGSFLLTSTSGRQHTVTFSAESSRSLLICLLWVLKNADETVLQKWFTDLSVLQLNRLLDLLYLCVSCFEYKGKKVFERMNSLTFKKSKDMRAKLEEAILGSIGARQEMVRRSRGQLERSPSGSAFGSQENLRWRKDMTHWRQNTEKLDKSRAEIEHEALIDGNLATEANLIILDTLEIIVQTVSVTESKESILGGVLKVLLQSMACNQSAVYLQHCFATQRALVSKFPELLFEEETEQCADLCLRLLRHCSSSISTIRSHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERSNHAEAAQCLVHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTESGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLSTIHGKLQEAFSKIVHQSTGWERMFGTYFRVGFYGTKFGDLDEQEFVYKEPAITKLAEISHRLEGFYGERFGEDVLEVIKDSNPVDKCKLDPNKAYIQITYVEPFFDTYEMKDRITYFDKNYNLRRFMYCTPFTLDGRAHGELHEQFKRKTILTTSHAFPYIKTRVNVTHKEEIILTPIEVAIEDMQKKTQELAFATHQDPADPKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPGDPKLFRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIPQLYKAVLPVTCHRDSFSRMSLRKMEL", "length": 2131 }, "evidence": [ { "id": "RGD:1309790", "url": "https://alliancegenome.org/gene/RGD:1309790#orthology", "database": "AGR" }, { "id": "HGNC:19190", "url": "https://alliancegenome.org/gene/HGNC:19190#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050302-15", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050302-15#orthology", "database": "AGR" }, { "id": "MGI:1914549", "url": "https://alliancegenome.org/gene/MGI:1914549#orthology", "database": "AGR" }, { "id": "FB:FBgn0031216", "url": "https://alliancegenome.org/gene/FB:FBgn0031216#orthology", "database": "AGR" }, { "id": "Q9VPI9", "url": "https://omabrowser.org/oma/group/Q9VPI9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M9PMX5-1", "protein_name": "Dedicator of cytokinesis protein 7 isoform X9", "gene_name": "dock7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAERRAFAQKISRTVAAEVRKQIAGQYGGSPQLLKNLSVGGNATSNAIPLTEAVEPVDFEEYLITHPPIIESGPLRDLIEFPPDDIEVLYTPRECRTLSQAVPEEGENDPHVRDCTRSYTEDWAIVNRKYHKLGTAFNPNTLDKQKERQRGLPKQVFESDELPDQSSYQDDQDDLKRRSMSIDDTPRGSWACSIFDLKNSQPDALLPHLLDRVPNEEIDRHNEDLRKSNRHRELFALHPALDEEEPIERHCVPDVPKEHFGQRLLVKCLSLKFEIEIEPIFATLALYDVKEKKKISENFYFDLNSEQTKGMLRPHIPSAAISTLARSAVFSITYPSQDVFLVIKLEKVLQQGDIGECAEPYMVFKESDAAKNKEKLEKLRSQAEQFCQRLGRYRMPFAWTAIHLMNIVNSAGSLERDTEVDMGLSERKGSWSERRNSSIVGRRSLERTTSGDESCSLTSFRPATLTVTNFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPHYCLTPDLLQVKPYPDSRVRPTKEILEFPARDVYVPNTTYRNLLYVNPQSLNFANRQGSARNITVKVQFMNGEDPSNAMPVISGKSSCAEFSKEAYTSVVYHNRSPDFYDEVKIKLPASLTDHHHILFTFYHVSCQQKQNTPLETPVGYTWIPMLQNGRLRTGHFCLPVSLEKPPQSYSVLSPDVPLPGMKWVDNHRGVFNVEVVAASTIHTQDQYLDKFFALVHALDEHMFPVRIGDMRIMENNLETELKSSIAALNSSQLEPVVRFLHLLLDKLVLLMVRPPVIAGQIVNLGQASFEVMASIVNRLHKYLDTSQDMHGRNSLLSSYIHYVFRLPNMDPNSPSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIIGSKGLDRSNSWVHTMGCKSAPWGTSPGSTSDTKQAMERSGNRMSSHTESASFLQTLTGRLPTKKLFHEELALQWVVSSGSVREGALQQAWFFFELMVKSIIHHLYFTDRLESPRKNRFPERFMDDITALVSTIAGDIVSRFQKDLELVERLNTSLAFFLNDLLSVMDRGFVFTLIKTYWKQVSTKLYALQNPTLESLRLDFLRIVCSHEHYVTLNLPFSLLTPPASPSPSVSSATSQSSGFSTHVQDQKIANMFELSVPFREQHYLAGLILTELAVILEPEADGSVPWMFGLHKKVISVVHNLLSSHDSDPRYADPEVKARVALLYLPLIGIVMETLPQLHDFTESLNQWGRGGPGTEEQEAEGNSMISQTVAMAIAGTSVPQMSRPSSFLLNPQATRQHGSFSAESSRSLLICLLWVLKNADEMVLQKWFTDLSVSQLNRLLDLLYLCVSCFEYKGKKAFERMNSLTFKKSKDMKAKLEEAILGSIGARQEMVRRSRGQLERSPSGSAFGSQENLRWRKDMTHWRQTSEKMDKTRAELEHEAIIDGNLATEANLIILDTLEIIVQTVSVTESKESILGGVLKVLLHSMACNQSALYLQHCFATQRALVSKFPELLFEEETEQCADLCLRLLRNCSSSIGTIRAHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERNNHAEAAQCLVHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTEAGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLATIHGKLQEAFGKIVHQSTGWERMFGTYFRVGFYGSKFGDLDEQEFVYKEPAITKLAEISHRLESFYGERFGEDQVEVIKDSNPVDKCKLDPNKAFIQITYVEPYFDTYEMKDRITYFDKNYNLRRFVYCTPFTLDGRAHGDLHEQFKRKTILTTSHAFPYIKTRINIIHKEEIISTPIEVAIEDMQKKTQELAFATHQDPSDAKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPSDPKLYRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIPQLYKPVLQVNSHRDSFSRMSLRKLDM", "length": 2131 }, "evidence": [ { "id": "RGD:1309790", "url": "https://alliancegenome.org/gene/RGD:1309790#orthology", "database": "AGR" }, { "id": "HGNC:19190", "url": "https://alliancegenome.org/gene/HGNC:19190#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050302-15", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050302-15#orthology", "database": "AGR" }, { "id": "MGI:1914549", "url": "https://alliancegenome.org/gene/MGI:1914549#orthology", "database": "AGR" }, { "id": "FB:FBgn0031216", "url": "https://alliancegenome.org/gene/FB:FBgn0031216#orthology", "database": "AGR" }, { "id": "Q9VPI9", "url": "https://omabrowser.org/oma/group/Q9VPI9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TJM6-1", "protein_name": "Dedicator of cytokinesis protein 7 isoform X1", "gene_name": "dock6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MATLTSERRAFAHKINRTVASEVRKQVSREYGSPQMSKKRAGAHQPVPLTEVVEPVDYEEYVSSHPPGAEPGPLRQLLEFPRDDLELVLQERECVTIEPPVPEEDSLDPRVRDALGVYTDDWLIIQRKYQCYSTLQTPHNSERQREKQKGLVKQTFELDEAAIERQDEQDDPKRHSVSLDDTPRGSWASSIFDLKNSIPDALLPSVLERTAAEEMDRRNADNRQQGRHNHLLGLYPAPDEDEAVERCAIPEVPKEHSGQRIMVKCLSLKFEIEIEPIFGSLALYDVREKKKISEDFHFDLNSDQMKGLLRPHNPHVAISTLARSAIFSITYPSPEIFLVIKLEKVLQQGDIGECCEPYMVMKESDSIKHKEKLEKLRAQAEQMCSRLGGFRMPFAWTAIHLLNIVSSVGGLDRSDSDSDTERKGTWNERKKKGFERMSVGEDMCNFTNFRPATLTVTNFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPVTAQLKIDISPAPEAPHYCLSPELLHVKPYPDPRVRPTKEVLEFPARYVYTPHTTYRNLLYVYPQSVNFSSRQGSVRNIAVKVQFMAGEDPSQAMPVIFGKSSCAEFYKEAYTPVIYHNKSPEFYEEVKMKIPANLTDNHHLLFTFYHISCQPKQNTLLETPVGYTWIPLMQHGRLRSGSFSLPVSVEKPPPSYSVLTPDVQLPGMKWVDNHKGVFNVEVKAASSVHTQDPHLDKFFTLVYVLEEYSFPFRLKDVIITESNVEAELKASMAALKGALLDTCVRFLHQLMSKLILLIVHPPVIAGQIVNLGRAAFEAMALLVNQIHKNLEGNQDHHGRNNLLSSYIHYCFHLPTTEPVSPPAVGAAAYDLPIHYATLSRATSRPSALLLSRSKSISNSNPDLASTPATPDEEVQRIIGSKGIDRSHSWVNSAYAPGGSRAVLRRNPNSSCELKQASERACNRMSAYIETTSLLCPPSRQIAKKLLHEELALQWVVSTSTVREASLQQAWFFFQLMVKSMSHHLFLSSRLDMPRRQRFPDRFVDDIAALVCAISADIASRYHKDVELVERLNSSLAFFLNDLLSLMDRGFVFNLVRSYYKQINNKLHTAQNPSSLTALRMDFIRIICSHEHYVILNLPCATLSPPASPSPSTSSTTSQSSAFSSHAQDQGVVSMFELSVPFRQQHFLSGLLLAELSLILEPDGESVFFLHKKAISALHSLLCSHDADPRYTDPQVRSHVAQLYLPLIPIIMETLPKLHDFTDTSPQRVRHASALADDNDPDNGTISQSVAMAIAGSPLPHSKANPFTLPSVAGRQCGVLSAECSRTLLVCFLWVWKNADAGLLERWVSDLSVPQINRLLDLLHLCLSCFEYKGKKALERINSLTFKKSQDMKARLEEAILGTIGARQEMVRRCRERSPYGGQENVRWRKNVTHWRQNADRVDKTKAEVEQESVVDGNLATEAALIALDTLEIIVKTVVMSELKESVLGGVLRVLLHSMAGNQSALFLQHCFSTQRALVYKFPEMLFEEDTELCADLCLRLLRHCSSSVSSVRSHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQTFNEEHLRRSLKTILTYAEDDLELRDSPFPEQVQDLVFNLHMILTDTVKMKEHQQDPEMLIDLMYRIAKGYQNSPDLRLTWLQNMAGKHSEKGNHAEAAHCLVHSAALVAEYLNMLEDCRYLPIGCVSFQSISSNVLEESAVSDDILSPEEEGICSGKYFSESGLVGLLEQAAASFNMAAMYEAINEVYKILCPIHEANRDFKKLASVHGKLQDAFNKVYNQSSGWERMFGTYFRVGFYGCRFGDLDEQEFVYKEPSITKLAEISHRLEEFYSERFGDEVVAIIKDSNPVDKNKLDPNKAYLQITYVEPFFDTYELKERITYFDKNYNLRTFMYCTPFTLDGRAHGDLHEQYKRKTILTTSHAFPYIKTRINVIHKEEIILMPMEVAIEDMQKKTQELAFATHQDPADPKMLQMVLQGCVGTTVNQGPLEVAQVFLSEIPEDPKLFRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYHRELERNYLKLKEALFPLINRKIPQLYRPLPLPTLPTQRNSLSRSSFRRLEC", "length": 2114 }, "evidence": [ { "id": "HGNC:19189", "url": "https://alliancegenome.org/gene/HGNC:19189#orthology", "database": "AGR" }, { "id": "MGI:1914789", "url": "https://alliancegenome.org/gene/MGI:1914789#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QJ79-1", "protein_name": "Dedicator of cytokinesis protein 8 isoform X1", "gene_name": "dock8", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASLPASERRAFALKINRHSSAEIRRHFSGVSHGSLPHHRHSYNASGSFCFNVPQSYEAVEPVDLDEFLMSQLRSGDAEVMQELGEFPDDDLDVELVERECRTIRPTIAEEGVELDSHVRDCVQSYTQPWLVVSRRSQGYGWISYSDRTDSNKILQRQTFESDVQPDKQEQLDKSPSLTALCDDSARTTLTSSDFNLRALQPDQRVESVLRFSSPEELDRFNQESRQSNRYGELFGLYPPIDEEDAVAIRPIPDCPKEHFGQRILVRCQTVKFEIEIEPLFATMALYDLKEKKKISENFNFDLNSDQMKGFLRTHTPQVDTSTLSRSAIFSISYPSPDIYLVIKIEKVLQQGEIGDCAEPYMVLKESDTTKNRDKLEKLRNQAEGFCQRLGRYRMPLAFATVNIMSVINSTLERETSDTDSINGRGSMDKKGLPRRNSDRFSLMEDNYILSGFKPAVTMCTFIKQEGERLSDEDLFKFLADIKRSSSQRRVKIIPGYLKLEVLPAPDTVPGCLSPELIPVKPVSEKNQRPIKEVLEFPSKEVYVPHNIYRNLLYVYPLRLNLTNRLTSARNITVKIQFMSGEDSSCAMPVIFGKSSGPEFLTEVYTPVTYHNRSPDFYDEIKILLPARLTDKHHLLFTFFHISCQQKQNQTGSVEALIGYSWLPMLNNDRLQTSQQCLPIVLDKLPINYSLHTPEKLPAQVPPVKWLENHKGLFNLELQAVSSVQTQDSHLERFFTLCHALEGKSTFPIRVRDEKIQENMFEHELKLSIISLSSAGLEPLVLFLHQVLDKLFRLIMQPMVIAGQTANLAQIAFESVVSVINSLHNSQELAKDHQGRNCLLATYLYFVFRLPDTQYEIHTSGTGGLMAHPEGRYSTLTRTTATTVGFMLLQSRIRSSSNPDIPAPLSPEDTEVNNILGKVLNHPGSRMSTAANASNSPQSSTGSTRPTNKKLFHEELALQMVVSTGVCRENVYKYAWFFFEVLVKSMSQHVSQLDKKTVSRRNRFSDRFKDDITTIVNVVTAEIGNILVKQQKELEQAEKVNISLAFFLYDLMSLMDRGFVFQLVKNYCNQMAAKSVNMATLISMRLEFLRVLCSHEHYLNLSLFFSSPSSAPASPSPSVSSQTSSSCSFQDNKIAAMFDLSQDFKQRHYLTGLLLTELSTALDIESEGGRVQQKAINATYSLLCAHDLDQRCSRSEVKAKIAALYLPLVGIIIDSINYLDFTVSDSRSGKGKSGGPEEDPDNIATINQSVAMAIAGNPFNTLTRNALVSMASVSVKTTNMLTAETSRNLLMCFLWIIKNADQNLIQRWTVDMPSSQLSRLLELLAICTSCFEYRGKQSSDKVSTQALQKSQQAKARLEEALLGGIGARGEMMKRVGVQGNDRTLGLRENLRWRKDLTQWRQTNDRQDKSKAELDQEAIISGNLATETNLIVLDLLEMIVQAVPLADCKDNVVGGVLKVLLHSLTCNQSTTYLSHCFSTLRALIVKFGDLLFEEEAEQCADLCQKVLHYCSSCVDGNRSQACATLYLIMRYSYSSASNFSRVKMQVTMSLASLVGKSSDIHEEYLRRSFRTILAYAEEDTEMQSTQLPSQVDELLRNLNSILSDTVKMKEFQKDPEMLMDLMYRIAKGYQTSPDLRLTWLQNMAEKHNGRKCFTESAMCLVHAAALVAEYLSMLEDHKYLPVGSVTFQNISPNVLEESAVSDDILSPDEDGVCSGRYFTENGLVGLLEQAAELFSNGGLFEAVNEVYKVIVPILEAHRDFRKLASTHDKLQRAFDNIIQKGHKRMFGTYFRVGFYGSKFGDLDEQEFIYKEPGITHLPEISHRLENFYSQCFGDGVLEMIKDSTPVDRNKLSPNKAYIQITFVEPYFDDYEMKDRLTNFEKNFNLRRFMYTTPFTKSGRPRGELNEQYKRKTILTTMHAFPYIKTRINVIQKEEFDLTPIEVAIEDMQKKTRELAEATHREKPDAVMLQMVLQGSVTATVNQGPLEVAQVFLNEIPADPKLFRHHNKLRLCFKEFILRCGEAIEKNKQLITPDQKEYQQEMKKNYNKLRENLRPMLERKIPELYKPIIKPRIENRDSFKRHSLRRTQDEHS", "length": 2090 }, "evidence": [ { "id": "HGNC:19191", "url": "https://alliancegenome.org/gene/HGNC:19191#orthology", "database": "AGR" }, { "id": "MGI:1921396", "url": "https://alliancegenome.org/gene/MGI:1921396#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8C147-1", "protein_name": "Dedicator of cytokinesis protein 8", "gene_name": "Dock8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATLPSAERRAFALKINRYSSSEIRKQFTLPPNLGQYHRHSISTSGFPSLQLPQLYEPVEPVDFEGLVMTHLNSLDAELAQELGDLTDDDLHVAFTPKECRTLQHSLPEEGVELDPHVRDCVQTYIREWLIVNRKNQGSSEFCSFKKTGSRRDFQKTLQKQTFESETLECSEPDTQTGPRHPLNVLCDVSGKGPLTSCDFDLRSLQPDERLENLLQLVSAEDFEKEKEEARKTNRPAELFALYPPVDEEDAVEIRPVPECPKEHLGNRILVKVLTLKFEIEIEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSIDPSSQARSAVFSVTYPSSDIYLVVKIEKVLQQGEIADCAEPYMIIKESDGGKSKEKVEKLKLQAESFCQRLGKYRMPFAWAPISLASFFNISTLERESTDVEPGVGRNSVGEKRSLSQSRRPSERTLSLEENGVGSNFKATTLATNIFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIPGSLRLEISPAPDVMNCCLTPEMLPVKPFPENRTRPHKEILEFPIREVYVPHTVYRNLLYVYPQRLNFASKLASARNITIKIQFMCGEDPSNAMPVIFGKSSGPEFLQEVYTAITYHNKSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQQKQGASGESLLGYSWLPILLNERLQTGSYCLPVALEKLPPNYSIHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDNHLEKFFTLCHSLESQVSFPIRVLDQKITESTLEHELKLSIICLNSSRLEPLVLFLHLVLDKLFQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLRKDQHGRNCLLASYVHYVFRLPELHRDTSKSGGPTTVVPDPRYHTYGRTSAAAVSSKLMQARVMSSSNPDLTGSHCAADEEVKNIMSSKIADRNCSRMSYYCSGNSDAPGSTAAPRPVSKKHFHEELALQMVVSTGVVRETVFKYAWFFFELLVKSMAQYVHNLDKRDSFRRTRFSDRFKDDITTIVNVVTSEIAALLVKPQKESEQAEKINISLAFFLYDLLSIMDRGFVFNLIKHYCSQLSAKLNILPTLISMRLEFLRILCSHEHYLNLNLLFMNTDTAPASPCPSISSQNSSSCSSFQDQKIASMFDLTPEYRQQHFLTGLLFTELAVALDAEGDGISRVQRKAVSAIHSLLCSHDLDPRCRKPEVKVKIAALYLPLVGIILDALPQLYDFTDARSGRSRASGSYEEQDVANGINQNVALAIAGNHFNLKTSGAMLSSLPYKQYNMLNADTTRHLMICFLWIMKNADQSLIRKWIADLPSMQLNRILDLLFICVSCFEYKGKQSSDKVSNQVLQKSRDVKAKLEEALLRGEGARGEMMRRRIPGTDRFPGINENLRWRKEQTQWRQANEKLDKTKAELDQEALISGNLATEANLIILDMQENIIQASSALDCKDSLLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKFGDLLFEEEMEQCADLCQRVLHHCSSSMDVTRSQACATLYLLMRFSFGATSNFARVKMQVTMALASLVGKAPDFNEEHLRRSLRTILAYSEEDTAMQTTPFPMQVEELLCNLNSILYDTVKMREFQEDPEMLMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKKKCFTEAAMCLVHAAALVAEYLSMLEDHSYLPVGSVSFQNISSNVLEESAVSDDTLSPDEDGVCSGRYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHRDFRKLTSTHDKLQKAFDNIINKDHKRMFGTYFRVGFYGSRFGDLDEQEFVYKEPAITKLPEISHRLEGFYGQCFGAEFVEVIKDSTPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRFMYTTPFTLEGRPRGELHEQHRRNTVLTTMHAFPYIKTRIRVSQKEEFVLTPIEVAIEDMKKKTLQLAVATHQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHNKLRLCFKEFIMRCGEAVEKNRRLITAEQREYQQELKKNYNKLRDSLRPMIERKIPELYKPIFRVDSQKRDSFHRSSFRKCETQLSQGS", "length": 2100 }, "evidence": [ { "id": "HGNC:19191", "url": "https://alliancegenome.org/gene/HGNC:19191#orthology", "database": "AGR" }, { "id": "MGI:1921396", "url": "https://alliancegenome.org/gene/MGI:1921396#orthology", "database": "AGR" }, { "id": "RGD:1561588", "url": "https://alliancegenome.org/gene/RGD:1561588#orthology", "database": "AGR" }, { "id": "FB:FBgn0031216", "url": "https://alliancegenome.org/gene/FB:FBgn0031216#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NF50-1", "protein_name": "Dedicator of cytokinesis protein 8", "gene_name": "DOCK8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATLPSAERRAFALKINRYSSAEIRKQFTLPPNLGQYHRQSISTSGFPSLQLPQFYDPVEPVDFEGLLMTHLNSLDVQLAQELGDFTDDDLDVVFTPKECRTLQPSLPEEGVELDPHVRDCVQTYIREWLIVNRKNQGSPEICGFKKTGSRKDFHKTLPKQTFESETLECSEPAAQAGPRHLNVLCDVSGKGPVTACDFDLRSLQPDKRLENLLQQVSAEDFEKQNEEARRTNRQAELFALYPSVDEEDAVEIRPVPECPKEHLGNRILVKLLTLKFEIEIEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVAASSQARSAVFSVTYPSSDIYLVVKIEKVLQQGEIGDCAEPYTVIKESDGGKSKEKIEKLKLQAESFCQRLGKYRMPFAWAPISLSSFFNVSTLEREVTDVDSVVGRSSVGERRTLAQSRRLSERALSLEENGVGSNFKTSTLSVSSFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIPGLLRLEISTAPEIINCCLTPEMLPVKPFPENRTRPHKEILEFPTREVYVPHTVYRNLLYVYPQRLNFVNKLASARNITIKIQFMCGEDASNAMPVIFGKSSGPEFLQEVYTAVTYHNKSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQQKQGASVETLLGYSWLPILLNERLQTGSYCLPVALEKLPPNYSMHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDNHLEKFFTLCHSLESQVTFPIRVLDQKISEMALEHELKLSIICLNSSRLEPLVLFLHLVLDKLFQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLSKDQHGRNCLLASYVHYVFRLPEVQRDVPKSGAPTALLDPRSYHTYGRTSAAAVSSKLLQARVMSSSNPDLAGTHSAADEEVKNIMSSKIADRNCSRMSYYCSGSSDAPSSPAAPRPASKKHFHEELALQMVVSTGMVRETVFKYAWFFFELLVKSMAQHVHNMDKRDSFRRTRFSDRFMDDITTIVNVVTSEIAALLVKPQKENEQAEKMNISLAFFLYDLLSLMDRGFVFNLIRHYCSQLSAKLSNLPTLISMRLEFLRILCSHEHYLNLNLFFMNADTAPTSPCPSISSQNSSSCSSFQDQKIASMFDLTSEYRQQHFLTGLLFTELAAALDAEGEGISKVQRKAVSAIHSLLSSHDLDPRCVKPEVKVKIAALYLPLVGIILDALPQLCDFTVADTRRYRTSGSDEEQEGAGAINQNVALAIAGNNFNLKTSGIVLSSLPYKQYNMLNADTTRNLMICFLWIMKNADQSLIRKWIADLPSTQLNRILDLLFICVLCFEYKGKQSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRRRAPGNDRFPGLNENLRWKKEQTHWRQANEKLDKTKAELDQEALISGNLATEAHLIILDMQENIIQASSALDCKDSLLGGVLRVLVNSLNCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQCFDLCHQVLHHCSSSMDVTRSQACATLYLLMRFSFGATSNFARVKMQVTMSLASLVGRAPDFNEEHLRRSLRTILAYSEEDTAMQMTPFPTQVEELLCNLNSILYDTVKMREFQEDPEMLMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKKKCYTEAAMCLVHAAALVAEYLSMLEDHSYLPVGSVSFQNISSNVLEESVVSEDTLSPDEDGVCAGQYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHREFRKLTLTHSKLQRAFDSIVNKDHKRMFGTYFRVGFFGSKFGDLDEQEFVYKEPAITKLPEISHRLEAFYGQCFGAEFVEVIKDSTPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRFMYTTPFTLEGRPRGELHEQYRRNTVLTTMHAFPYIKTRISVIQKEEFVLTPIEVAIEDMKKKTLQLAVAINQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHNKLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYNKLKENLRPMIERKIPELYKPIFRVESQKRDSFHRSSFRKCETQLSQGS", "length": 2099 }, "evidence": [ { "id": "HGNC:19191", "url": "https://alliancegenome.org/gene/HGNC:19191#orthology", "database": "AGR" }, { "id": "MGI:1921396", "url": "https://alliancegenome.org/gene/MGI:1921396#orthology", "database": "AGR" }, { "id": "RGD:1561588", "url": "https://alliancegenome.org/gene/RGD:1561588#orthology", "database": "AGR" }, { "id": "FB:FBgn0031216", "url": "https://alliancegenome.org/gene/FB:FBgn0031216#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R1A4-1", "protein_name": "Dedicator of cytokinesis protein 7", "gene_name": "Dock7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAERRAFAQKISRTVAAEVRKQISGQYSGSPQLLKNLNIVGNISHHTTVPLTEAVDPVDLEDYLVTHPLSGDSGPLRDLVEFPPDDIEVVYSPRDCRTLVSAVPEESEMDPHVRDCIRSYTEDWAVVVRKYHKLGTGFNPNTLDKQKERQKGLPRQVFESDEAPDGSSYQDEQDDLKRRSMSIDDTPRGSWACSIFDLKNSLPDALLPNLLDRTPNEEIDHQNDDQRKSNRHKELFALHPSPDEEEPIERLSVPDVPKEHFGQRLLVKCLSLKFEIEIEPIFASLALYDVKEKKKISENFYFDLNSEQMKGLLRPHVPPAAITTLARSAIFSITYPSQDVFLVIKLEKVLQQGDIGECAEPYMIFKEADATKNKEKLEKLKSQADQFCQRLGKYRMPFAWTAIHLMNIVSSAGSLERDSTEVEISTGERKGSWSERRNSSLVGRRSLERTTSGDDACNLTSFRPATLTVANFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPHYCLTPELLQVKLYPDSRVRPTREILEFPARDVYVPNTTYRNLLYIYPQSLNFANRQGSARNITVKVQFMYGEDPSNAMPVIFGKSSCSEFSKEAYTAVVYHNRSPDFHEEIKVKLPATLTDHHHLLFTFYHVSCQQKQNTPLETPVGYTWIPMLQNGRLKTGQFCLPVSLEKPPQAYSVLSPEVPLPGMKWVDNHKGVFNVEVVAVSSIHTQDPYLDKFFALVNALDEHMFPVRIGDMRIMENNLESELKSSISALNSSQLEPVVRFLHLLLDKLILLVVRPPVIAGQIVNLGQASFEAMASIINRLHKNLEGNHDQHGRNNLLASYIYYVFRLPNTYPNSPSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIIGSKGLDRSNSWVNTGPKAAPWGSNPSPSAESTQAMDRSCNRMSSHTETSSFLQTLTGRLPTKKLFHEELALQWVVCSGSVRESALQQAWFFFELMVKSMVHHLYFNDKLDAPRESRFPERFMDDIAALVSTIAGDVVSRFQKDTEMVERLNTSLAFFLNDLLSVMDRGFVFSLIKSCYKQVSAKLYSLPNPSVLVSLRLDFLRIICSHEHYVTLNLPCSLLTPPASPSPSVSSATSQSSGFSTSVQDQKIANMFELSLPFRQQHYLAGLVLTELALILDPDAEGLFGLHKKVINMVHNLLSTHDSDPRYSDPQIKARVAMLYLPLIGIIMETVPQLYDFTESHNQRGRPICIAPDDYDSESGSMISQTVAMAIAGTSVPQLTRPGSFLLTSTSGRQHTTFSAESSRSLLICLLWVLKNADETVLQKWFTDLSVLQLNRLLDLLYLCVSCFEYKGKKVFERMNSLTFKKSKDMRAKLEEAILGSIGARQEMVRRSRGQLERSPSGSAFGSQENLRWRKDMTHWRQNSEKLDKSRAEIEHEALIDGNLATEANLIILDTLEIIVQTVSVTESKESILGGVLKVLLQSMACNQSAVYLQHCFATQRALVSKFPELLFEEETEQCADLCLRLLRHCSSSISTIRSHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERSNHAEAAQCLVHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTESGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLSTIHGKLQEAFSKIVHQSTGWERMFGTYFRVGFYGTKFGDLDEQEFVYKEPAITKLAEISHRLEGFYGERFGEDVLEVIKDSNPVDKCKLDPNKAYIQITYVEPFFDTYEMKDRITYFDKNYNLRRFMYCTPFTLDGRAHGELHEQFKRKTILTTSHAFPYIKTRVNVTHKEEIILTPIEVAIEDMQKKTQELAFATHQDPADPKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPGDPKLFRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIPQLYKAVLPVTCHRDSFSRMSLRKMEL", "length": 2130 }, "evidence": [ { "id": "RGD:1309790", "url": "https://alliancegenome.org/gene/RGD:1309790#orthology", "database": "AGR" }, { "id": "HGNC:19190", "url": "https://alliancegenome.org/gene/HGNC:19190#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050302-15", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050302-15#orthology", "database": "AGR" }, { "id": "MGI:1914549", "url": "https://alliancegenome.org/gene/MGI:1914549#orthology", "database": "AGR" }, { "id": "FB:FBgn0031216", "url": "https://alliancegenome.org/gene/FB:FBgn0031216#orthology", "database": "AGR" }, { "id": "Q9VPI9", "url": "https://omabrowser.org/oma/group/Q9VPI9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8SAB7-1", "protein_name": "Guanine nucleotide exchange factor SPIKE 1", "gene_name": "SPK1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MENNNLGLRFRKLPRQPLALPKLDPLLDENLEQWPHLNQLVQCYGTEWVKDVNKYGHYENIRPDSFQTQIFEGPDTDTETEIRLASARSATIEEDVASISGRPFSDPGSSKHFGQPPLPAYEPAFDWENERAMIFGQRTPESPAASYSSGLKISVRVLSLAFQSGLVEPFFGSIALYNQERKEKLSEDFYFQIQPTEMQDAKLSSENRGVFYLDAPSASVCLLIQLEKTATEEGGVTSSVYSRKEPVHLTEREKQKLQVWSRIMPYRESFAWAVVPLFDNNLTTNTGESASPSSPLAPSMTASSSHDGVYEPIAKITSDGKQGYSGGSSVVVEISNLNKVKESYSEESIQDPKRKVHKPVKGVLRLEIEKHRNGHGDFEDLSENGSIINDSLDPTDRLSDLTLMKCPSSSSGGPRNGCSKWNSEDAKDVSRNLTSSCGTPDLNCYHAFDFCSTTRNEPFLHLFHCLYVYPVAVTLSRKRNPFIRVELRKDDTDIRKQPLEAIYPREPGVSLQKWVHTQVAVGARAASYHDEIKVSLPATWTPSHHLLFTFFHVDLQTKLEAPRPVVVGYASLPLSTYIHSRSDISLPVMRELVPHYLQESTKERLDYLEDGKNIFKLRLRLCSSLYPTNERVRDFCLEYDRHTLQTRPPWGSELLQAINSLKHVDSTALLQFLYPILNMLLHLIGNGGETLQVAAFRAMVDILTRVQQVSFDDADRNRFLVTYVDYSFDDFGGNQPPVYPGLATVWGSLARSKAKGYRVGPVYDDVLSMAWFFLELIVKSMALEQARLYDHNLPTGEDVPPMQLKESVFRCIMQLFDCLLTEVHERCKKGLSLAKRLNSSLAFFCYDLLYIIEPCQVYELVSLYMDKFSGVCQSVLHECKLTFLQIISDHDLFVEMPGRDPSDRNYLSSILIQELFLSLDHDELPLRAKGARILVILLCKHEFDARYQKAEDKLYIAQLYFPFVGQILDEMPVFYNLNATEKREVLIGVLQIVRNLDDTSLVKAWQQSIARTRLYFKLMEECLILFEHKKAADSILGGNNSRGPVSEGAGSPKYSERLSPAINNYLSEASRQEVRLEGTPDNGYLWQRVNSQLASPSQPYSLREALAQAQSSRIGASAQALRESLHPILRQKLELWEENVSATVSLQVLEITENFSSMAASHNIATDYGKLDCITTILTSFFSRNQSLAFWKAFFPIFNRIFDLHGATLMARENDRFLKQIAFHLLRLAVYRNDSVRKRAVIGLQILVKSSLYFMQTARLRALLTITLSELMSDVQVTHMKSDNTLEESGEARRLQQSLSEMADEAKSVNLLRECGLPDDTLLIIPEKFTENRWSWAEVKHLSDSLVLALDASLGHALLGSVMAMDRYAAAESFYKLGMAFAPVPDLHIMWLLHLCDAHQEMQSWAEAAQCAVAVAGVIMQALVARNDGVWSKDHVSALRKICPMVSGEFTTEASAAEVEGYGASKLTVDSAVKYLQLANKLFSQAELYHFCASILELVIPVYKSRKAYGQLAKCHTLLTNIYESILDQESNPIPFIDATYYRVGFYGEKFGKLDRKEYVYREPRDVRLGDIMEKLSHIYESRMDSNHILHIIPDSRQVKAEDLQAGVCYLQITAVDAVMEDEDLGSRRERIFSLSTGSVRARVFDRFLFDTPFTKNGKTQGGLEDQWKRRTVLQTEGSFPALVNRLLVTKSESLEFSPVENAIGMIETRTTALRNELEEPRSSDGDHLPRLQSLQRILQGSVAVQVNSGVLSVCTAFLSGEPATRLRSQELQQLIAALLEFMAVCKRAIRVHFRLIGEEDQEFHTQLVNGFQSLTAELSHYIPAILSEL", "length": 1830 }, "evidence": [ { "id": "Q9VPI9", "url": "https://omabrowser.org/oma/group/Q9VPI9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q8VDR9-1", "protein_name": "Dedicator of cytokinesis protein 6", "gene_name": "Dock6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAASERRAFAHKINRTVAAEVRKQVSRERSGSPHSSRRSSSSLGVPLTEVIEPLDFEDVLLSRPPEVEPGPLRDLIEFPVDDLELLKQPRECRTTESGVPEDGQLDAQVRAAVEMYSEDWVIVRRRYQHLSTAYSPITTETQREWQKGLTCQVFEQDTPGDERTGPEDVDDPQHCSGSPEDTPRSSGASGIFSLRNLAADSLLPTLLEQAAPEDVDRRNEALRRQHRAPTLLTLYPAPDEDEAVERCSRPEPPREHFGQRILVKCLSLKFEIEIEPIFGTLALYDVREKKKISENFYFDLNSDSVKGLLRAHGTHPAISTLARSAIFSVTYPSPDIFLVVKLEKVLQQGDISECCEPYMVMKEADTAKNKEKLEKLRLAAEQFCTRLGRYRMPFAWTAVHLANIVSRPQDRDSDSEGERRPTWAERRRRGPQDRGYSGDDACSFSSFRPATLTVTNFFKQEAERLSDEDLFKFLADMRRPSSLLRRLRPVTAQLKLDISPAPENLHFCLSPDLLHVKPYPDPRGRPTKEILEFPAREVYAPHSCYRNLLFVYPHSLNFSSRQGSVRNLAVRIQYMAGEDQSQALPVIFGKSSCSEFTREAFTPVVYHNKSPEFYEEFKLRLPACVTENHHLFFTFYHVSCQPRPGTALETPVGFTWIPLLQHGRLRTGPFCLPVSVDQPPPSYSVLTPDVALPGMRWVDGHKGVFSVELTAVSSVHPQDPHLDKFFTLVHVLEEGIFPFRLKETVLSEGTMEQELRASLAALRLASPEPLVAFSHLVLDKLVRLVVRPPIICGQMVNLGRGAFEAMAHVASLVHRNLEAVQDSRGHCPLLASYVHYAFRLPGGDLSLPGEAPPATVQAATLARGSGRPASLYLARSKSISSSNPDLAVVPGSVDDEVSRILASKGVDRSHSWVNSAYAPGGSKAVLRRVPPYCGADPRQLLHEELALQWVVSGSAVRELVLQHAWFFFQLMVKSMELHLLLGQRLDTPRKLRFPGRFLDDIAALVASVGLEVITRVHKDMKLAERLNASLAFFLSDLLSIADRGYIFSLVRAHYKQVATRLQSAPNPTALLTLRMDFTRILCSHEHYVTLNLPCCPLSPPASPSPSVSSTTSQSSTFSSQAPDPKVTSMFELSGPFRQQHFLSGLLLTELALALDPEAEGASLLHKKAISAVHSLLCSHDVDSRYAEATVKAKVAELYLPLLSLARDTLPQLHGFAEGSGQRSRLASMLDSDTEGEGDIGSTINPSVAMAIAGGPLAPGSRTSISQGPSTAARSGCPLSAESSRTLLVCVLWVLKNAEPTLLQRWAADLALPQLGRLLDLLYLCLAAFEYKGKKAFERINSLTFKKSLDMKARLEEAILGTIGARQEMVRRSRERSPFGNQENVRWRKSATHWRQTSDRVDKTKDEMEHEALVDGNLATEASLVVLDTLETIVQTVMLSEARESILSAVLKVVLYSLGSAQSALFLQHGLATQRALVSKFPELLFEEDTELCADLCLRLLRHCGSRISTIRMHASASLYLLMRQNFEIGHNFARVKMLVTMSLSSLVGTTQNFSEEHLRKSLKTILTYAEEDIGLRDSTFAEQVQDLMFNLHMILTDTVKMKEHQEDPEMLMDLMYRIARGYQGSPDLRLTWLQNMAGKHAELGNHAEAAQCMVHAAALVAEYLALLEDSRHLPVGCVSFQNVSSNVLEESAISDDILSPDEEGFCSGKNFTELGLVGLLEQAAGYFTMGGLYEAVNEVYKNLIPILEAHRDYKKLAAVHGKLQEAFTKIMHQSSGWERVFGTYFRVGFYGTRFGDLDEQEFVYKEPSITKLAEISHRLEEFYTERFGDDVVEIIKDSNPVDKSKLDPQKAYIQITYVEPHFDTYELKDRVTYFDRNYGLRAFLFCTPFTPDGRAHGELAEQHKRKTLLSTEHAFPYIKTRIRVCHREETVLTPVEVAIEDMQKKTRELAFATEQDPPDAKMLQMVLQGSVGPTVNQGPLEVAQVFLSEIPEDPKLFRHHNKLRLCFKDFCKKCEDALRKNKALIGPDQKEYHRELERHYSRLREALQPLLTQRLPQLLAPSSTSLRSSMNRSSFRKADL", "length": 2080 }, "evidence": [ { "id": "HGNC:19189", "url": "https://alliancegenome.org/gene/HGNC:19189#orthology", "database": "AGR" }, { "id": "MGI:1914789", "url": "https://alliancegenome.org/gene/MGI:1914789#orthology", "database": "AGR" }, { "id": "RGD:1306517", "url": "https://alliancegenome.org/gene/RGD:1306517#orthology", "database": "AGR" }, { "id": "FB:FBgn0031216", "url": "https://alliancegenome.org/gene/FB:FBgn0031216#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96HP0-1", "protein_name": "Dedicator of cytokinesis protein 6", "gene_name": "DOCK6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAASERRAFAHKINRTVAAEVRKQVSRERSGSPHSSRRCSSSLGVPLTEVVEPLDFEDVLLSRPPDAEPGPLRDLVEFPADDLELLLQPRECRTTEPGIPKDEKLDAQVRAAVEMYIEDWVIVHRRYQYLSAAYSPVTTDTQRERQKGLPRQVFEQDASGDERSGPEDSNDSRRGSGSPEDTPRSSGASSIFDLRNLAADSLLPSLLERAAPEDVDRRNETLRRQHRPPALLTLYPAPDEDEAVERCSRPEPPREHFGQRILVKCLSLKFEIEIEPIFGILALYDVREKKKISENFYFDLNSDSMKGLLRAHGTHPAISTLARSAIFSVTYPSPDIFLVIKLEKVLQQGDISECCEPYMVLKEVDTAKNKEKLEKLRLAAEQFCTRLGRYRMPFAWTAVHLANIVSSAGQLDRDSDSEGERRPAWTDRRRRGPQDRASSGDDACSFSGFRPATLTVTNFFKQEAERLSDEDLFKFLADMRRPSSLLRRLRPVTAQLKIDISPAPENPHFCLSPELLHIKPYPDPRGRPTKEILEFPAREVYAPHTSYRNLLYVYPHSLNFSSRQGSVRNLAVRVQYMTGEDPSQALPVIFGKSSCSEFTREAFTPVVYHNKSPEFYEEFKLHLPACVTENHHLLFTFYHVSCQPRPGTALETPVGFTWIPLLQHGRLRTGPFCLPVSVDQPPPSYSVLTPDVALPGMRWVDGHKGVFSVELTAVSSVHPQDPYLDKFFTLVHVLEEGAFPFRLKDTVLSEGNVEQELRASLAALRLASPEPLVAFSHHVLDKLVRLVIRPPIISGQIVNLGRGAFEAMAHVVSLVHRSLEAAQDARGHCPQLAAYVHYAFRLPGTEPSLPDGAPPVTVQAATLARGSGRPASLYLARSKSISSSNPDLAVAPGSVDDEVSRILASKLLHEELALQWVVSSSAVREAILQHAWFFFQLMVKSMALHLLLGQRLDTPRKLRFPGRFLDDITALVGSVGLEVITRVHKDVELAEHLNASLAFFLSDLLSLVDRGFVFSLVRAHYKQVATRLQSSPNPAALLTLRMEFTRILCSHEHYVTLNLPCCPLSPPASPSPSVSSTTSQSSTFSSQAPDPKVTSMFELSGPFRQQHFLAGLLLTELALALEPEAEGAFLLHKKAISAVHSLLCGHDTDPRYAEATVKARVAELYLPLLSIARDTLPRLHDFAEGPGQRSRLASMLDSDTEGEGDIAGTINPSVAMAIAGGPLAPGSRASISQGPPTASRAGCALSAESSRTLLACVLWVLKNTEPALLQRWATDLTLPQLGRLLDLLYLCLAAFEYKGKKAFERINSLTFKKSLDMKARLEEAILGTIGARQEMVRRSRERSPFGNPENVRWRKSVTHWKQTSDRVDKTKDEMEHEALVEGNLATEASLVVLDTLEIIVQTVMLSEARESVLGAVLKVVLYSLGSAQSALFLQHGLATQRALVSKFPELLFEEDTELCADLCLRLLRHCGSRISTIRTHASASLYLLMRQNFEIGHNFARVKMQVTMSLSSLVGTTQNFSEEHLRRSLKTILTYAEEDMGLRDSTFAEQVQDLMFNLHMILTDTVKMKEHQEDPEMLIDLMYRIARGYQGSPDLRLTWLQNMAGKHAELGNHAEAAQCMVHAAALVAEYLALLEDHRHLPVGCVSFQNISSNVLEESAISDDILSPDEEGFCSGKHFTELGLVGLLEQAAGYFTMGGLYEAVNEVYKNLIPILEAHRDYKKLAAVHGKLQEAFTKIMHQSSGWERVFGTYFRVGFYGAHFGDLDEQEFVYKEPSITKLAEISHRLEEFYTERFGDDVVEIIKDSNPVDKSKLDSQKAYIQITYVEPYFDTYELKDRVTYFDRNYGLRTFLFCTPFTPDGRAHGELPEQHKRKTLLSTDHAFPYIKTRIRVCHREETVLTPVEVAIEDMQKKTRELAFATEQDPPDAKMLQMVLQGSVGPTVNQGPLEVAQVFLAEIPEDPKLFRHHNKLRLCFKDFCKKCEDALRKNKALIGPDQKEYHRELERNYCRLREALQPLLTQRLPQLMAPTPPGLRNSLNRASFRKADL", "length": 2047 }, "evidence": [ { "id": "HGNC:19189", "url": "https://alliancegenome.org/gene/HGNC:19189#orthology", "database": "AGR" }, { "id": "MGI:1914789", "url": "https://alliancegenome.org/gene/MGI:1914789#orthology", "database": "AGR" }, { "id": "RGD:1306517", "url": "https://alliancegenome.org/gene/RGD:1306517#orthology", "database": "AGR" }, { "id": "FB:FBgn0031216", "url": "https://alliancegenome.org/gene/FB:FBgn0031216#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q96N67-1", "protein_name": "Dedicator of cytokinesis protein 7", "gene_name": "DOCK7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAERRAFAQKISRTVAAEVRKQISGQYSGSPQLLKNLNIVGNISHHTTVPLTEAVDPVDLEDYLITHPLAVDSGPLRDLIEFPPDDIEVVYSPRDCRTLVSAVPEESEMDPHVRDCIRSYTEDWAIVIRKYHKLGTGFNPNTLDKQKERQKGLPKQVFESDEAPDGNSYQDDQDDLKRRSMSIDDTPRGSWACSIFDLKNSLPDALLPNLLDRTPNEEIDRQNDDQRKSNRHKELFALHPSPDEEEPIERLSVPDIPKEHFGQRLLVKCLSLKFEIEIEPIFASLALYDVKEKKKISENFYFDLNSEQMKGLLRPHVPPAAITTLARSAIFSITYPSQDVFLVIKLEKVLQQGDIGECAEPYMIFKEADATKNKEKLEKLKSQADQFCQRLGKYRMPFAWTAIHLMNIVSSAGSLERDSTEVEISTGERKGSWSERRNSSIVGRRSLERTTSGDDACNLTSFRPATLTVTNFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPHYCLTPELLQVKLYPDSRVRPTREILEFPARDVYVPNTTYRNLLYIYPQSLNFANRQGSARNITVKVQFMYGEDPSNAMPVIFGKSSCSEFSKEAYTAVVYHNRSPDFHEEIKVKLPATLTDHHHLLFTFYHVSCQQKQNTPLETPVGYTWIPMLQNGRLKTGQFCLPVSLEKPPQAYSVLSPEVPLPGMKWVDNHKGVFNVEVVAVSSIHTQDPYLDKFFALVNALDEHLFPVRIGDMRIMENNLENELKSSISALNSSQLEPVVRFLHLLLDKLILLVIRPPVIAGQIVNLGQASFEAMASIINRLHKNLEGNHDQHGRNSLLASYIHYVFRLPNTYPNSSSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIIGSKGLDRSNSWVNTGGPKAAPWGSNPSPSAESTQAMDRSCNRMSSHTETSSFLQTLTGRLPTKKLFHEELALQWVVCSGSVRESALQQAWFFFELMVKSMVHHLYFNDKLEAPRKSRFPERFMDDIAALVSTIASDIVSRFQKDTEMVERLNTSLAFFLNDLLSVMDRGFVFSLIKSCYKQVSSKLYSLPNPSVLVSLRLDFLRIICSHEHYVTLNLPCSLLTPPASPSPSVSSATSQSSGFSTNVQDQKIANMFELSVPFRQQHYLAGLVLTELAVILDPDAEGLFGLHKKVINMVHNLLSSHDSDPRYSDPQIKARVAMLYLPLIGIIMETVPQLYDFTETHNQRGRPICIATDDYESESGSMISQTVAMAIAGTSVPQLTRPGSFLLTSTSGRQHTTFSAESSRSLLICLLWVLKNADETVLQKWFTDLSVLQLNRLLDLLYLCVSCFEYKGKKVFERMNSLTFKKSKDMRAKLEEAILGSIGARQEMVRRSRGQLGTYTIASPPERSPSGSAFGSQENLRWRKDMTHWRQNTEKLDKSRAEIEHEALIDGNLATEANLIILDTLEIVVQTVSVTESKESILGGVLKVLLHSMACNQSAVYLQHCFATQRALVSKFPELLFEEETEQCADLCLRLLRHCSSSIGTIRSHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERSNHAEAAQCLVHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTESGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLSTIHGKLQEAFSKIVHQSTGWERMFGTYFRVGFYGTKFGDLDEQEFVYKEPAITKLAEISHRLEGFYGERFGEDVVEVIKDSNPVDKCKLDPNKAYIQITYVEPYFDTYEMKDRITYFDKNYNLRRFMYCTPFTLDGRAHGELHEQFKRKTILTTSHAFPYIKTRVNVTHKEEIILTPIEVAIEDMQKKTQELAFATHQDPADPKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPSDPKLFRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIPQLYKAVLPVTCHRDSFSRMSLRKMDL", "length": 2140 }, "evidence": [ { "id": "RGD:1309790", "url": "https://alliancegenome.org/gene/RGD:1309790#orthology", "database": "AGR" }, { "id": "HGNC:19190", "url": "https://alliancegenome.org/gene/HGNC:19190#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050302-15", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050302-15#orthology", "database": "AGR" }, { "id": "MGI:1914549", "url": "https://alliancegenome.org/gene/MGI:1914549#orthology", "database": "AGR" }, { "id": "FB:FBgn0031216", "url": "https://alliancegenome.org/gene/FB:FBgn0031216#orthology", "database": "AGR" }, { "id": "Q9VPI9", "url": "https://omabrowser.org/oma/group/Q9VPI9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "phagocytosis", "id": "GO:0006909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006909", "evidence": [ { "database": "UniProtKB", "id": "Q9VPI9", "url": "https://www.uniprot.org/uniprotkb/Q9VPI9" } ], "pmid": "" }, { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "Q9VPI9", "url": "https://www.uniprot.org/uniprotkb/Q9VPI9" } ], "pmid": "" }, { "name": "regulation of Rho protein signal transduction", "id": "GO:0035023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035023", "evidence": [ { "database": "UniProtKB", "id": "Q9VPI9", "url": "https://www.uniprot.org/uniprotkb/Q9VPI9" } ], "pmid": "" }, { "name": "encapsulation of foreign target", "id": "GO:0035010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035010", "evidence": [ { "database": "UniProtKB", "id": "Q9VPI9", "url": "https://www.uniprot.org/uniprotkb/Q9VPI9" } ], "pmid": "" }, { "name": "melanotic encapsulation of foreign target", "id": "GO:0035011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035011", "evidence": [ { "database": "UniProtKB", "id": "Q9VPI9", "url": "https://www.uniprot.org/uniprotkb/Q9VPI9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "Q9VPI9", "url": "https://www.uniprot.org/uniprotkb/Q9VPI9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1030, "end_pos": 1032, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1064, "end_pos": 1066, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1369, "end_pos": 1371, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1449, "end_pos": 1451, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1634, "end_pos": 1636, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1976, "end_pos": 1978, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2057, "end_pos": 2059, "annotation": "n_glycosylation_sequon" }, { "start_pos": 23, "end_pos": 25, "annotation": "n_glycosylation_sequon" }, { "start_pos": 359, "end_pos": 361, "annotation": "n_glycosylation_sequon" }, { "start_pos": 601, "end_pos": 603, "annotation": "n_glycosylation_sequon" }, { "start_pos": 729, "end_pos": 731, "annotation": "n_glycosylation_sequon" }, { "start_pos": 97, "end_pos": 99, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VPI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPI9" }, { "id": "PS51650", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51650" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2 DOCK-type", "eco_id": "ECO_0000259", "start_pos": 590, "end_pos": 759, "start_aa": "Arg", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q9VPI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPI9" }, { "id": "PS51651", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51651" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DOCKER", "eco_id": "ECO_0000259", "start_pos": 1609, "end_pos": 2044, "start_aa": "Lys", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1108 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1030, "end_pos": 1032 }, { "start_pos": 1064, "end_pos": 1066 }, { "start_pos": 1369, "end_pos": 1371 }, { "start_pos": 1449, "end_pos": 1451 }, { "start_pos": 1634, "end_pos": 1636 }, { "start_pos": 1976, "end_pos": 1978 }, { "start_pos": 2057, "end_pos": 2059 }, { "start_pos": 23, "end_pos": 25 }, { "start_pos": 359, "end_pos": 361 }, { "start_pos": 601, "end_pos": 603 }, { "start_pos": 729, "end_pos": 731 }, { "start_pos": 97, "end_pos": 99 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VPM0-1", "uniprot_ac": "Q9VPM0", "uniprot_id": "Q9VPM0_DROME", "mass": { "chemical_mass": 33498.0, "monoisotopic_mass": 33498.0 }, "refseq": { "ac": "NP_001259808", "name": "RNaseP protein p30, isoform B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259808" }, "gene_names": [ { "name": "Rpp30", "type": "recommended", "evidence": [ { "id": "Q9VPM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPM0" } ] }, { "name": "#19/1", "type": "synonym", "evidence": [ { "id": "NP_001259808", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259808" } ] }, { "name": "1", "type": "synonym", "evidence": [ { "id": "Q9VPM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPM0" } ] }, { "name": "CG11606", "type": "synonym", "evidence": [ { "id": "NP_001259808", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259808" }, { "id": "Q9VPM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPM0" } ] }, { "name": "Dmel\\CG11606", "type": 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"RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259808" } ] }, { "name": "coconut", "type": "synonym", "evidence": [ { "id": "NP_001259808", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259808" }, { "id": "Q9VPM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPM0" } ] }, { "name": "l(2)k01901", "type": "synonym", "evidence": [ { "id": "NP_001259808", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259808" }, { "id": "Q9VPM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPM0" } ] } ], "protein_names": [ { "name": "CG11606-PB", "type": "synonym", "evidence": [ { "id": "NP_001259808", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259808" } ] }, { "name": "RNaseP protein p30, isoform A", "type": "synonym", "evidence": [ { "id": "Q9VPM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPM0/entry#names_and_taxonomy" } ] }, { "name": "RNaseP protein p30, isoform B", "type": "synonym", "evidence": [ { "id": "NP_001259808", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259808" }, { "id": "Q9VPM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPM0/entry#names_and_taxonomy" } ] }, { "name": "Rpp30-PB", "type": "synonym", "evidence": [ { "id": "NP_001259808", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259808" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VPM0", "url": "https://www.uniprot.org/uniprotkb/Q9VPM0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Rpp30", "url": "https://www.uniprot.org/uniprotkb/Q9VPM0", "locus": { "chromosome": "2L", "start_pos": 251039, "end_pos": 252373, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0283652", "url": "https://www.ensemblgenomes.org/id/FBgn0283652" } ] } } ], "crossref": [ { "id": "FB:FBgn0283652", "url": "https://alliancegenome.org/gene/FB:FBgn0283652", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0283652", "url": "https://bgee.org/?page=gene&gene_id=FBgn0283652", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0283652", "url": "https://flybase.org/reports/FBgn0283652", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "44392", "url": "https://www.ncbi.nlm.nih.gov/gene/44392", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VPM0", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VPM0*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR002738", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002738", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016195", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016195", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG11606", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG11606", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CYGPGIT", "url": "https://omabrowser.org/oma/group/CYGPGIT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VPM0", "url": "https://www.orthodb.org/?gene=Q9VPM0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13031", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13031", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13031:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13031:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01876", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01876", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001259808", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259808", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VPM0", "url": "https://www.uniprot.org/uniprotkb/Q9VPM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VPM0-1", "url": "https://www.uniprot.org/uniprotkb/Q9VPM0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEQTRPFYDFSIPYNKDDSVLRALLNELVETGYKTVAIDQSFDHSKKDPGKRGSEMFPEPHKIEHLRKEFQDKLRILQRITILYVDVNVAHAMSVSHNLRKFNLIAGQPKTDAALTHCCTAFNGDLITFDPVAGSRLLVNRKAYQVAVRRGMFFEIKYAPSICDSNNRKDMIKIAQNYCTKGKSKNVIFSSGAAHEFQLRGPYDVANLAFIFGLSEDQGKNAVDGHCRELFLKAEARRLGKTIMFLKGNGPIIYSDSSEDEKSTEDEMKGLKPQIGKADAFEVKDGTEHAIKRLKVA", "length": 297, "header": "tr|Q9VPM0-1|Q9VPM0_DROME Isoform 1 of RNaseP protein p30, isoform A OS=Drosophila melanogaster OX=7227 GN=Rpp30 PE=1 SV=1 CANONICAL=Q9VPM0-1" }, "isoforms": [ { "isoform_ac": "Q9VPM0-1", "url": "https://www.uniprot.org/uniprotkb/Q9VPM0/entry#Q9VPM0-1", "sequence": { "sequence": "MEQTRPFYDFSIPYNKDDSVLRALLNELVETGYKTVAIDQSFDHSKKDPGKRGSEMFPEPHKIEHLRKEFQDKLRILQRITILYVDVNVAHAMSVSHNLRKFNLIAGQPKTDAALTHCCTAFNGDLITFDPVAGSRLLVNRKAYQVAVRRGMFFEIKYAPSICDSNNRKDMIKIAQNYCTKGKSKNVIFSSGAAHEFQLRGPYDVANLAFIFGLSEDQGKNAVDGHCRELFLKAEARRLGKTIMFLKGNGPIIYSDSSEDEKSTEDEMKGLKPQIGKADAFEVKDGTEHAIKRLKVA", "length": 297, "header": "tr|Q9VPM0-1|Q9VPM0_DROME Isoform 1 of RNaseP protein p30, isoform A OS=Drosophila melanogaster OX=7227 GN=Rpp30 PE=1 SV=1 CANONICAL=Q9VPM0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VPM0", "url": "https://www.uniprot.org/uniprotkb/Q9VPM0" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VPM0", "url": "https://www.uniprot.org/uniprotkb/Q9VPM0" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPM0", "url": "https://www.uniprot.org/uniprotkb/Q9VPM0" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPM0", "url": "https://www.uniprot.org/uniprotkb/Q9VPM0" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VPM0", "url": "https://www.uniprot.org/uniprotkb/Q9VPM0" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VPM0", "url": "https://www.uniprot.org/uniprotkb/Q9VPM0" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VPM0", "url": "https://www.uniprot.org/uniprotkb/Q9VPM0" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPM0", "url": "https://www.uniprot.org/uniprotkb/Q9VPM0" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPM0", "url": "https://www.uniprot.org/uniprotkb/Q9VPM0" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VPM0", "url": "https://www.uniprot.org/uniprotkb/Q9VPM0" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VPM0", "url": "https://www.uniprot.org/uniprotkb/Q9VPM0" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], 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"database": "AGR" }, { "id": "FB:FBgn0283652", "url": "https://alliancegenome.org/gene/FB:FBgn0283652#orthology", "database": "AGR" }, { "id": "SGD:S000001104", "url": "https://alliancegenome.org/gene/SGD:S000001104#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0ZKW3-1", "protein_name": "Ribonuclease P protein subunit p30", "gene_name": "RPP30", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGFADLNVPQGADRKAVQSLLEAAAHLGYSAVALNHIIDFKEKKQEIAKPVSPSELFPSLPIVQGTSKRLKVLTRLTLVVSDPSHCNLLRSTSTNIRLYDIIAVFPKTEKLFHIACTTLDVDLVCINVTEKLPFYFRRPPVNMAIDRGIYFELLYTPAIKDSTMRRYTISNAISLMQICKGKNIVISSAAERPLELRGPYDVANLGLLFGLSEGEAKAAVSTNCRATILHGETRKSACGVVYTVKKLHKVEEEETVPACKKAKTQA", "length": 267 }, "evidence": [ { "id": "Q9VPM0", "url": "https://omabrowser.org/oma/group/Q9VPM0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3H3V1-1", "protein_name": 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"MAAFADLDLRAGSDLKALRGLVETAAHLGYSVVAINHIVDFKEKKREIEKPIAVSELFTTLPIVQGKSRPIKILTRLTIIVTDPAHCNVLRATSSRVRLYDIVAVFPKTEKLFHVACTHLDVDLVCITVTEKLPFYFKRPPVNVAIERGLGFELVYGPAIRDATMRRYTISNALNLMQICKGKNVILSSAAERPLEIRGPYDVANLGLLFGLSENDGKAAVSTNCRAVFLHGETRKTAFGIISTVKKPRPSEADDESLPVCKKAKCEG", "length": 268 }, "evidence": [ { "id": "MGI:1859683", "url": "https://alliancegenome.org/gene/MGI:1859683#orthology", "database": "AGR" }, { "id": "HGNC:17688", "url": "https://alliancegenome.org/gene/HGNC:17688#orthology", "database": "AGR" }, { "id": "RGD:1595116", "url": "https://alliancegenome.org/gene/RGD:1595116#orthology", "database": "AGR" }, { "id": "FB:FBgn0283652", "url": "https://alliancegenome.org/gene/FB:FBgn0283652#orthology", "database": "AGR" }, { "id": "SGD:S000001104", "url": "https://alliancegenome.org/gene/SGD:S000001104#orthology", "database": "AGR" }, { "id": "Q9VPM0", "url": "https://omabrowser.org/oma/group/Q9VPM0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P38786-1", "protein_name": "Ribonuclease P/MRP protein subunit RPP1", "gene_name": "RPP1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLVDLNVPWPQNSYADKVTSQAVNNLIKTLSTLHMLGYTHIAINFTVNHSEKFPNDVKLLNPIDIKRRFGELMDRTGLKLYSRITLIIDDPSKGQSLSKISQAFDIVAALPISEKGLTLSTTNLDIDLLTFQYGSRLPTFLKHKSICSCVNRGVKLEIVYGYALRDVQARRQFVSNVRSVIRSSRSRGIVIGSGAMSPLECRNILGVTSLIKNLGLPSDRCSKAMGDLASLVLLNGRLRNKSHKQTIVTGGGSGNGDDVVNDVQGIDDVQTIKVVKRSMDAEQLGHASKRHKP", "length": 293 }, "evidence": [ { "id": "MGI:1859683", "url": "https://alliancegenome.org/gene/MGI:1859683#orthology", "database": "AGR" }, { "id": "HGNC:17688", "url": "https://alliancegenome.org/gene/HGNC:17688#orthology", "database": "AGR" }, { "id": "RGD:1595116", "url": "https://alliancegenome.org/gene/RGD:1595116#orthology", "database": "AGR" }, { "id": "FB:FBgn0283652", "url": "https://alliancegenome.org/gene/FB:FBgn0283652#orthology", "database": "AGR" }, { "id": "SGD:S000001104", "url": "https://alliancegenome.org/gene/SGD:S000001104#orthology", "database": "AGR" }, { "id": "Q9VPM0", "url": "https://omabrowser.org/oma/group/Q9VPM0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P78346-1", "protein_name": "Ribonuclease P protein subunit p30", "gene_name": "RPP30", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVFADLDLRAGSDLKALRGLVETAAHLGYSVVAINHIVDFKEKKQEIEKPVAVSELFTTLPIVQGKSRPIKILTRLTIIVSDPSHCNVLRATSSRARLYDVVAVFPKTEKLFHIACTHLDVDLVCITVTEKLPFYFKRPPINVAIDRGLAFELVYSPAIKDSTMRRYTISSALNLMQICKGKNVIISSAAERPLEIRGPYDVANLGLLFGLSESDAKAAVSTNCRAALLHGETRKTAFGIISTVKKPRPSEGDEDCLPASKKAKCEG", "length": 268 }, "evidence": [ { "id": "MGI:1859683", "url": "https://alliancegenome.org/gene/MGI:1859683#orthology", "database": "AGR" }, { "id": "HGNC:17688", "url": "https://alliancegenome.org/gene/HGNC:17688#orthology", "database": "AGR" }, { "id": "RGD:1595116", "url": "https://alliancegenome.org/gene/RGD:1595116#orthology", "database": "AGR" }, { "id": "FB:FBgn0283652", "url": "https://alliancegenome.org/gene/FB:FBgn0283652#orthology", "database": "AGR" }, { "id": "SGD:S000001104", "url": "https://alliancegenome.org/gene/SGD:S000001104#orthology", "database": "AGR" }, { "id": "Q9VPM0", "url": "https://omabrowser.org/oma/group/Q9VPM0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3SZ21-1", "protein_name": "Ribonuclease P protein subunit p30", "gene_name": "RPP30", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAVFADLDLRAGSDLKALRGLVENAAHLGYSVVAINHVVEFKEKKQEIEKPVAVSELFTTLPIVQGKSKPIKILTRLTIIVSDPSHCNVLRATSSRVRLYDIVAVFPKTEKLFHVACTHLDVDLVCITVTEKLPFYFKRPPINVAIDRGVGFELLYSPAIKDSTMRRYTISNALNLMQVCKGKNVIISSAAERPLEIRGPYDVANLGLLFGLSESDAKAAVSTNCRAVLLHGETRKTAFGIISTVKKPRTSEADDDSLPACKKAKCES", "length": 268 }, "evidence": [ { "id": "Q9VPM0", "url": "https://omabrowser.org/oma/group/Q9VPM0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleolar ribonuclease P complex", "id": "GO:0005655", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005655", "evidence": [ { "database": "UniProtKB", "id": "Q9VPM0", "url": "https://www.uniprot.org/uniprotkb/Q9VPM0" } ], "pmid": "" }, { "name": "multimeric ribonuclease P complex", "id": "GO:0030681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030681", "evidence": [ { "database": "UniProtKB", "id": "Q9VPM0", "url": "https://www.uniprot.org/uniprotkb/Q9VPM0" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VPM0", "url": "https://www.uniprot.org/uniprotkb/Q9VPM0" } ], "pmid": "" }, { "name": "ribonuclease MRP complex", "id": "GO:0000172", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000172", "evidence": [ { "database": "UniProtKB", "id": "Q9VPM0", "url": "https://www.uniprot.org/uniprotkb/Q9VPM0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q9VPM0", "url": "https://www.uniprot.org/uniprotkb/Q9VPM0" } ], "pmid": "" }, { "name": "ribonuclease P RNA binding", "id": "GO:0033204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033204", "evidence": [ { "database": "UniProtKB", "id": "Q9VPM0", "url": "https://www.uniprot.org/uniprotkb/Q9VPM0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "RNA processing", "id": "GO:0006396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006396", "evidence": [ { "database": "UniProtKB", "id": "Q9VPM0", "url": "https://www.uniprot.org/uniprotkb/Q9VPM0" } ], "pmid": "" }, { "name": "tRNA processing", "id": "GO:0008033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008033", "evidence": [ { "database": "UniProtKB", "id": "Q9VPM0", "url": "https://www.uniprot.org/uniprotkb/Q9VPM0" } ], "pmid": "" }, { "name": "tRNA 5'-leader removal", "id": "GO:0001682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001682", "evidence": [ { "database": "UniProtKB", "id": "Q9VPM0", "url": "https://www.uniprot.org/uniprotkb/Q9VPM0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VPN3-1", "uniprot_ac": "Q9VPN3", "uniprot_id": "Q9VPN3_DROME", "mass": { "chemical_mass": 13677.0, "monoisotopic_mass": 13677.0 }, "refseq": { "ac": "NP_608516", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608516" }, "gene_names": [ { "name": "Dmel\\CG11562", "type": "recommended", "evidence": [ { "id": "Q9VPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPN3" } ] }, { "name": "BcDNA:RE44650", "type": "synonym", "evidence": [ { "id": "NP_608516", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608516" }, { "id": "Q9VPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPN3" } ] }, { "name": "CG11562", "type": "synonym", "evidence": [ { "id": "NP_608516", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608516" }, { "id": "Q9VPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPN3" } ] }, { "name": "Dmel\\CG11562", "type": "synonym", "evidence": [ { "id": "NP_608516", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608516" } ] }, { "name": "Dmel_CG11562", "type": "synonym", "evidence": [ { "id": "Q9VPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPN3" } ] } ], "protein_names": [ { "name": "Protein PET117 homolog, mitochondrial", "type": "recommended", "evidence": [ { "id": "Q9VPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPN3/entry#names_and_taxonomy" } ] }, { "name": "CG11562-PA", "type": "synonym", "evidence": [ { "id": "NP_608516", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608516" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_608516", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608516" } ] } ], "function": [], "disease": [ { "disease_id": "DOID:0070504", "recommended_name": { "id": "DOID:0070504", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070504", "name": "mitochondrial complex IV deficiency nuclear type 19", "description": "A COX deficiency, benign infantile mitochondrial myopathy that has_material_basis_in homozygous mutation in the PET117 gene on chromosome 20p11.23." }, "synonyms": [ { "id": "DOID:0070504", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070504", "name": "MC4DN19", "description": "" }, { "id": "MONDO:0033654", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0033654", "name": "mitochondrial complex IV deficiency, nuclear type 19", "description": "Any mitochondrial complex IV deficiency in which the cause of the disease is a mutation in the PET117 gene. It is characterized by the onset of symptoms in infancy or early childhood. Affected individuals show global developmental delay and developmental regression with a loss of acquired motor and language skills. Additional features include motor dysfunction, such as hypokinesia and pyramidal signs. More variable features may include recurrent infections with immunodeficiency and possibly protein-losing enteropathy." }, { "id": "MONDO:0033654", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0033654", "name": "MC4DN19", "description": "" }, { "id": "MONDO:0033654", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0033654", "name": "mitochondrial complex IV deficiency, nuclear type 19", "description": "" }, { "id": "MIM:619063", "resource": "MIM", "url": "https://www.omim.org/entry/619063", "name": "Mitochondrial complex IV deficiency, nuclear type 19", "description": "Mitochondrial complex IV deficiency, nuclear type 19" } ], "unlinked_id_list": [], "evidence": [ { "id": "0070504", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070504" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VPN3", "url": "https://www.uniprot.org/uniprotkb/Q9VPN3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG11562", "url": "https://www.uniprot.org/uniprotkb/Q9VPN3", "locus": { "chromosome": "2L", "start_pos": 293222, "end_pos": 292419, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0031247", "url": "https://www.ensemblgenomes.org/id/FBgn0031247" } ] } } ], "crossref": [ { "id": "FB:FBgn0031247", "url": "https://alliancegenome.org/gene/FB:FBgn0031247", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0031247", "url": "https://bgee.org/?page=gene&gene_id=FBgn0031247", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0031247", "url": "https://flybase.org/reports/FBgn0031247", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "33200", "url": "https://www.ncbi.nlm.nih.gov/gene/33200", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VPN3", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VPN3*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR031568", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031568", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG11562", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG11562", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QGGTTNH", "url": "https://omabrowser.org/oma/group/QGGTTNH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VPN3", "url": "https://www.orthodb.org/?gene=Q9VPN3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28163", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28163", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28163:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28163:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15786", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15786", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_608516", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608516", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VPN3", "url": "https://www.uniprot.org/uniprotkb/Q9VPN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VPN3-1", "url": "https://www.uniprot.org/uniprotkb/Q9VPN3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTASRVTLGLAVSISTAIIGYVHYKQSADRLRLHDGVLRDVEQQQRRKHENTYTLQQQIDMTKQLKAREASSNSSDTPVPPSTHRAQSNLQAEKPAVQNEGEAFRGVPQGGTTNHDGSPPTDIA", "length": 125, "header": "tr|Q9VPN3-1|Q9VPN3_DROME Isoform 1 of Protein PET117 homolog, mitochondrial OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG11562 PE=1 SV=1 CANONICAL=Q9VPN3-1" }, "isoforms": [ { "isoform_ac": "Q9VPN3-1", "url": "https://www.uniprot.org/uniprotkb/Q9VPN3/entry#Q9VPN3-1", "sequence": { "sequence": "MSTASRVTLGLAVSISTAIIGYVHYKQSADRLRLHDGVLRDVEQQQRRKHENTYTLQQQIDMTKQLKAREASSNSSDTPVPPSTHRAQSNLQAEKPAVQNEGEAFRGVPQGGTTNHDGSPPTDIA", "length": 125, "header": "tr|Q9VPN3-1|Q9VPN3_DROME Isoform 1 of Protein PET117 homolog, mitochondrial OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG11562 PE=1 SV=1 CANONICAL=Q9VPN3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VPN3", "url": "https://www.uniprot.org/uniprotkb/Q9VPN3" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VPN3", "url": "https://www.uniprot.org/uniprotkb/Q9VPN3" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPN3", "url": "https://www.uniprot.org/uniprotkb/Q9VPN3" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPN3", "url": "https://www.uniprot.org/uniprotkb/Q9VPN3" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VPN3", "url": "https://www.uniprot.org/uniprotkb/Q9VPN3" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VPN3", "url": "https://www.uniprot.org/uniprotkb/Q9VPN3" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VPN3", "url": "https://www.uniprot.org/uniprotkb/Q9VPN3" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPN3", "url": "https://www.uniprot.org/uniprotkb/Q9VPN3" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPN3", "url": "https://www.uniprot.org/uniprotkb/Q9VPN3" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VPN3", "url": "https://www.uniprot.org/uniprotkb/Q9VPN3" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VPN3", "url": "https://www.uniprot.org/uniprotkb/Q9VPN3" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], 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[ { "id": "NP_608523", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608523" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_608523", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608523" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VPP8", "url": "https://www.uniprot.org/uniprotkb/Q9VPP8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG13692", "url": "https://www.uniprot.org/uniprotkb/Q9VPP8", "locus": { "chromosome": "2L", "start_pos": 422489, "end_pos": 421771, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0031254", "url": "https://www.ensemblgenomes.org/id/FBgn0031254" } ] } } ], "crossref": [ { "id": "FB:FBgn0031254", "url": "https://alliancegenome.org/gene/FB:FBgn0031254", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0031254", "url": "https://bgee.org/?page=gene&gene_id=FBgn0031254", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0031254", "url": "https://flybase.org/reports/FBgn0031254", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "33216", "url": "https://www.ncbi.nlm.nih.gov/gene/33216", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006689", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006689", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG13692", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG13692", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ETTFSMP", "url": "https://omabrowser.org/oma/group/ETTFSMP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VPP8", "url": "https://www.orthodb.org/?gene=Q9VPP8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46688", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46688", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46688:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46688:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00025", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00025", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_608523", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608523", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VPP8", "url": "https://www.uniprot.org/uniprotkb/Q9VPP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VPP8-1", "url": "https://www.uniprot.org/uniprotkb/Q9VPP8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTCICLGPKRAGKTHLLKALQDPESIDETTFSMPTIGTGIYRIHFPTKSPNGDKNKPPPSEAPANIPHGGKNLPKSIQILEIGGSMAPLWRQYFEDVKKLIYVVDTSNLCQISAAGVLFYSILTEPRLQHNTKILLVLAKMDYSYRQMRNEALLMLQMQKLQKQIRQQVTIVEASAVTKVGLDPIYDWLQRP", "length": 193, "header": "tr|Q9VPP8-1|Q9VPP8_DROME Isoform 1 of ADP-ribosylation factor-like protein 16 OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG13692 PE=4 SV=1 CANONICAL=Q9VPP8-1" }, "isoforms": [ { "isoform_ac": "Q9VPP8-1", "url": "https://www.uniprot.org/uniprotkb/Q9VPP8/entry#Q9VPP8-1", "sequence": { "sequence": "MSTCICLGPKRAGKTHLLKALQDPESIDETTFSMPTIGTGIYRIHFPTKSPNGDKNKPPPSEAPANIPHGGKNLPKSIQILEIGGSMAPLWRQYFEDVKKLIYVVDTSNLCQISAAGVLFYSILTEPRLQHNTKILLVLAKMDYSYRQMRNEALLMLQMQKLQKQIRQQVTIVEASAVTKVGLDPIYDWLQRP", "length": 193, "header": "tr|Q9VPP8-1|Q9VPP8_DROME Isoform 1 of ADP-ribosylation factor-like protein 16 OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG13692 PE=4 SV=1 CANONICAL=Q9VPP8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VPP8", "url": "https://www.uniprot.org/uniprotkb/Q9VPP8" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VPP8", "url": "https://www.uniprot.org/uniprotkb/Q9VPP8" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPP8", "url": "https://www.uniprot.org/uniprotkb/Q9VPP8" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPP8", "url": "https://www.uniprot.org/uniprotkb/Q9VPP8" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VPP8", "url": "https://www.uniprot.org/uniprotkb/Q9VPP8" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VPP8", "url": "https://www.uniprot.org/uniprotkb/Q9VPP8" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VPP8", "url": "https://www.uniprot.org/uniprotkb/Q9VPP8" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPP8", "url": "https://www.uniprot.org/uniprotkb/Q9VPP8" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPP8", "url": "https://www.uniprot.org/uniprotkb/Q9VPP8" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VPP8", "url": "https://www.uniprot.org/uniprotkb/Q9VPP8" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VPP8", "url": "https://www.uniprot.org/uniprotkb/Q9VPP8" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG13692", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG13692", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AHL5-1", "protein_name": "ADP-ribosylation factor like GTPase 16", "gene_name": "Arl16", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCLLLGAAGVGKTLLVKRLQKLSSGDGKGDLGEPPPTRPTVGTNLTDIVAHRKITIRELGGCMSPIWSSYYGNCHSLLFMMDASNPTQLSASCMQLLGLLSAEELAKASVLILFNKIDLPSYMTVEEIKSLMRLPDIIACAKQNITTVEISARNGTGLATVLLWLRNQHRHSS", "length": 173 }, "evidence": [ { "id": "RGD:1590059", "url": "https://alliancegenome.org/gene/RGD:1590059#orthology", "database": "AGR" }, { "id": "HGNC:27902", "url": "https://alliancegenome.org/gene/HGNC:27902#orthology", "database": "AGR" }, { "id": "MGI:1917567", "url": "https://alliancegenome.org/gene/MGI:1917567#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070410-114", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070410-114#orthology", "database": "AGR" }, { "id": "FB:FBgn0031254", "url": "https://alliancegenome.org/gene/FB:FBgn0031254#orthology", "database": "AGR" }, { "id": "Q9VPP8", "url": "https://omabrowser.org/oma/group/Q9VPP8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V1ALR4-1", "protein_name": "ARF like GTPase 16", "gene_name": "ARL16", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGAARPGPTCLLLGATGVGKSLLGKRLRNIRASWGSRGAGPGWGCAARFCPVLNAPAQLCSRDGAKELGEPPATLPTVGTNLTDLTLHRRVTLRELGGCMGPIWPSYYGECSAVLFVIDAANPTQVSSSCVQLLSLLSAEQLAAVPVLILFNKIDLPCYMSLVEMKSLFRMQDIVSCAMQPITILETSARDGTGLADVLQWLQTTLRDPS", "length": 211 }, "evidence": [ { "id": "Q9VPP8", "url": "https://omabrowser.org/oma/group/Q9VPP8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "B1ATY8-1", "protein_name": "ADP-ribosylation factor-like protein 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"Protein Classification" ] }, { "id": "FBgn0031279", "url": "https://flybase.org/reports/FBgn0031279", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "33252", "url": "https://www.ncbi.nlm.nih.gov/gene/33252", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VPT2", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VPT2*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR018484", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018484", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018485", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018485", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG3544", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3544", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GCVFWSD", "url": "https://omabrowser.org/oma/group/GCVFWSD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VPT2", "url": "https://www.orthodb.org/?gene=Q9VPT2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10196", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10196", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10196:SF57", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10196:SF57", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00370", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00370", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02782", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02782", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001259842", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259842", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "10964", "url": "https://www.rhea-db.org/rhea/10964", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q9VPT2", "url": "https://www.uniprot.org/uniprotkb/Q9VPT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VPT2-1", "url": "https://www.uniprot.org/uniprotkb/Q9VPT2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCHRIKQDYSGNSYLGLHLGTQLFRALILDSKLNVTYVAQIRYDVDLPEFKTTNGILSDGGPGEFLANPVMWVKALDMLMDCLVKQGADMHTVVSIAGAAQQHGCVFWSELGLRRLCNLNVNLRLHEQITESAFELTRTPTWRDSSTDVQVREMEHTVGGPAELSKITGSRAYTRFTGPQIRKVYTQCPEQYERTSRISLISSFLASLLIGGIASIDYSDGSGMNLLDIRKKKWSAACLDACAPDLARRLMKPIPSSRLQGRIGDYYVKRWNFRPDCMVVASTGSKASELAGLLVENDFLMLSLDTSDVVVMPLKKAPRLEDGHVMCHPTRRDEYMGLLCFQNGGLTRKAICEDVAGGSWRHFYEMLDATPSGNNGNVAVHFRDREIIPTAKGTLRWDAHISPMSAECIRGLHRFSTPEIEVRALIEGQIMHHWSIAHEMGFHHTPNTKIIVVGEDSRCQSVLQIVADIFNAPVYQRTGVEVSLLGCAFRARYAFYEHRESACNCHSCMMPTGRRTRLSFDEFFRDVPSGLKLAAEPTPGCDKIYKPLIERCSQICQLLASKSSVYFFHPNV", "length": 572, "header": "tr|Q9VPT2-1|Q9VPT2_DROME Isoform 1 of Xylulose kinase OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG3544 PE=3 SV=1 CANONICAL=Q9VPT2-1" }, "isoforms": [ { "isoform_ac": "Q9VPT2-1", "url": "https://www.uniprot.org/uniprotkb/Q9VPT2/entry#Q9VPT2-1", "sequence": { "sequence": "MCHRIKQDYSGNSYLGLHLGTQLFRALILDSKLNVTYVAQIRYDVDLPEFKTTNGILSDGGPGEFLANPVMWVKALDMLMDCLVKQGADMHTVVSIAGAAQQHGCVFWSELGLRRLCNLNVNLRLHEQITESAFELTRTPTWRDSSTDVQVREMEHTVGGPAELSKITGSRAYTRFTGPQIRKVYTQCPEQYERTSRISLISSFLASLLIGGIASIDYSDGSGMNLLDIRKKKWSAACLDACAPDLARRLMKPIPSSRLQGRIGDYYVKRWNFRPDCMVVASTGSKASELAGLLVENDFLMLSLDTSDVVVMPLKKAPRLEDGHVMCHPTRRDEYMGLLCFQNGGLTRKAICEDVAGGSWRHFYEMLDATPSGNNGNVAVHFRDREIIPTAKGTLRWDAHISPMSAECIRGLHRFSTPEIEVRALIEGQIMHHWSIAHEMGFHHTPNTKIIVVGEDSRCQSVLQIVADIFNAPVYQRTGVEVSLLGCAFRARYAFYEHRESACNCHSCMMPTGRRTRLSFDEFFRDVPSGLKLAAEPTPGCDKIYKPLIERCSQICQLLASKSSVYFFHPNV", "length": 572, "header": "tr|Q9VPT2-1|Q9VPT2_DROME Isoform 1 of Xylulose kinase OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG3544 PE=3 SV=1 CANONICAL=Q9VPT2-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 538, "start_aa": "Thr", "end_pos": 538, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr538", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VPT2", "url": "https://www.uniprot.org/uniprotkb/Q9VPT2" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VPT2", "url": "https://www.uniprot.org/uniprotkb/Q9VPT2" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPT2", "url": "https://www.uniprot.org/uniprotkb/Q9VPT2" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPT2", "url": "https://www.uniprot.org/uniprotkb/Q9VPT2" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VPT2", "url": "https://www.uniprot.org/uniprotkb/Q9VPT2" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VPT2", "url": "https://www.uniprot.org/uniprotkb/Q9VPT2" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VPT2", "url": "https://www.uniprot.org/uniprotkb/Q9VPT2" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPT2", "url": "https://www.uniprot.org/uniprotkb/Q9VPT2" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPT2", "url": "https://www.uniprot.org/uniprotkb/Q9VPT2" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VPT2", "url": "https://www.uniprot.org/uniprotkb/Q9VPT2" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VPT2", "url": "https://www.uniprot.org/uniprotkb/Q9VPT2" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG3544", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3544", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "O75191-1", "protein_name": "Xylulose kinase", "gene_name": "XYLB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEHAPRRCCLGWDFSTQQVKVVAVDAELNVFYEESVHFDRDLPEFGTQGGVHVHKDGLTVTSPVLMWVQALDIILEKMKASGFDFSQVLALSGAGQQHGSIYWKAGAQQALTSLSPDLRLHQQLQDCFSISDCPVWMDSSTTAQCRQLEAAVGGAQALSCLTGSRAYERFTGNQIAKIYQQNPEAYSHTERISLVSSFAASLFLGSYSPIDYSDGSGMNLLQIQDKVWSQACLGACAPHLEEKLSPPVPSCSVVGAISSYYVQRYGFPPGCKVVAFTGDNPASLAGMRLEEGDIAVSLGTSDTLFLWLQEPMPALEGHIFCNPVDSQHYMALLCFKNGSLMREKIRNESVSRSWSDFSKALQSTEMGNGGNLGFYFDVMEITPEIIGRHRFNTENHKVAAFPGDVEVRALIEGQFMAKRIHAEGLGYRVMSKTKILATGGASHNREILQVLADVFDAPVYVIDTANSACVGSAYRAFHGLAGGTDVPFSEVVKLAPNPRLAATPSPGASQVYEALLPQYAKLEQRILSQTRGPPE", "length": 536 }, "evidence": [ { "id": "MGI:2142985", "url": "https://alliancegenome.org/gene/MGI:2142985#orthology", "database": "AGR" }, { "id": "HGNC:12839", "url": "https://alliancegenome.org/gene/HGNC:12839#orthology", "database": "AGR" }, { "id": "RGD:1307372", "url": "https://alliancegenome.org/gene/RGD:1307372#orthology", "database": "AGR" }, { "id": "FB:FBgn0031279", "url": "https://alliancegenome.org/gene/FB:FBgn0031279#orthology", "database": "AGR" }, { "id": "SGD:S000003426", "url": "https://alliancegenome.org/gene/SGD:S000003426#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P42826-1", "protein_name": "Xylulose kinase", "gene_name": "XKS1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLCSVIQRQTREVSNTMSLDSYYLGFDLSTQQLKCLAINQDLKIVHSETVEFEKDLPHYHTKKGVYIHGDTIECPVAMWLEALDLVLSKYREAKFPLNKVMAVSGSCQQHGSVYWSSQAESLLEQLNKKPEKDLLHYVSSVAFARQTAPNWQDHSTAKQCQEFEECIGGPEKMAQLTGSRAHFRFTGPQILKIAQLEPEAYEKTKTISLVSNFLTSILVGHLVELEEADACGMNLYDIRERKFSDELLHLIDSSSKDKTIRQKLMRAPMKNLIAGTICKYFIEKYGFNTNCKVSPMTGDNLATICSLPLRKNDVLVSLGTSTTVLLVTDKYHPSPNYHLFIHPTLPNHYMGMICYCNGSLARERIRDELNKERENNYEKTNDWTLFNQAVLDDSESSENELGVYFPLGEIVPSVKAINKRVIFNPKTGMIEREVAKFKDKRHDAKNIVESQALSCRVRISPLLSDSNASSQQRLNEDTIVKFDYDESPLRDYLNKRPERTFFVGGASKNDAIVKKFAQVIGATKGNFRLETPNSCALGGCYKAMWSLLYDSNKIAVPFDKFLNDNFPWHVMESISDVDNENWDRYNSKIVPLSELEKTLI", "length": 600 }, "evidence": [ { "id": "MGI:2142985", "url": "https://alliancegenome.org/gene/MGI:2142985#orthology", "database": "AGR" }, { "id": "HGNC:12839", "url": "https://alliancegenome.org/gene/HGNC:12839#orthology", "database": "AGR" }, { "id": "RGD:1307372", "url": "https://alliancegenome.org/gene/RGD:1307372#orthology", "database": "AGR" }, { "id": "FB:FBgn0031279", "url": "https://alliancegenome.org/gene/FB:FBgn0031279#orthology", "database": "AGR" }, { "id": "SGD:S000003426", "url": "https://alliancegenome.org/gene/SGD:S000003426#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q3MIF4-1", "protein_name": "Xylulose kinase", "gene_name": "Xylb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAERAGRRCCLGWDFSTQQVKVVAVDAELNVFYEDSVHFDRDLPEFGTQGGVHVHKDRLTVTSPVLMWVQALDLILEKMKASGFDFSQVLALSGAGQQHGSVYWKTGASLALSSLSPALLLHQQLQACFSVSDCPIWMDSSTTAQCHQLEAAVGGAQALSCLTGSRAYERFTGNQISKIFQKNPEAYSNSERISLVSSFAASLFLGRYSPIDYSDGSGMNLLQIQEKVWSQACLDACAPHLKEKLGSPVPSCSVVGAISSYYVQRYGFPPGCKVVAFTGDNPASLAGMRLEEGDVAVSLGTSDTLFLWLQKPMPALEGHIFCNPVDARQYMALLCFKNGSLMREKIRDESASCSWNKFSKALQSTEMGNNGNLGFYFDVMEITPEIIGCHRFNADNMEVSAFPGDVEIRALVEGQFMAKRIHAEGLGYRIMPKTKILATGGASHNKDILQVLADVFGAPVYVIDTTSSACVGSAYRAFHGLAGGTGVAFSEVVKSAPQPSLAATPNPGASQVYAALLPRYAELEQRILSKARGPLE", "length": 536 }, "evidence": [ { "id": "MGI:2142985", "url": "https://alliancegenome.org/gene/MGI:2142985#orthology", "database": "AGR" }, { "id": "HGNC:12839", "url": "https://alliancegenome.org/gene/HGNC:12839#orthology", "database": "AGR" }, { "id": "RGD:1307372", "url": "https://alliancegenome.org/gene/RGD:1307372#orthology", "database": "AGR" }, { "id": "FB:FBgn0031279", "url": "https://alliancegenome.org/gene/FB:FBgn0031279#orthology", "database": "AGR" }, { "id": "SGD:S000003426", "url": "https://alliancegenome.org/gene/SGD:S000003426#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3TNA1-1", "protein_name": "Xylulose kinase", "gene_name": "Xylb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDARTHRRAAGTPRALAERAGRRCCLGWDFSTQQVKVVAVDAELNVFYEDSVHFDRDLPEFGTQGGVHVHKDRLTVTSPVLMWVQALDLILGKMKSSGFDFSQVLALSGAGQQHGSVYWKTGASLALSSLSPALPLHQQLQSCFSISDCPIWMDSSTTAQCHQLEAAVGGAQALSCLTGSRAYERFTGNQIAKLFQKNPEAYSHSERISLVSSFAASLFLGGYSPIDYSDGSGMNLLQIQEKVWSQACLDVCAPHLEEKLGSPVPSCSVVGTISSYYVQRYGFPPGCKVVAFSGDNPASLAGMRLEEGDIAVSLGTSDTLFLWLQKPMPALEGHIFCNPVDPQHYMALLCFKNGSLMREKIRDESASCSWNKFSKALKSTAMGNNGNLGFYFDVMEITPEIIGRHRFNAENMEVSAFPGDVEIRALIEGQFMAKRIHAEGLGYRVMPKTKILATGGASHNKDILQVLADVFGAPVYVIDTTSSACVGSAYRAFHGLAGGTGVAFSEVVKSAPQPSLAATPNPGASQVYAALLPRYSALEQRILSTAQRPLE", "length": 551 }, "evidence": [ { "id": "MGI:2142985", "url": "https://alliancegenome.org/gene/MGI:2142985#orthology", "database": "AGR" }, { "id": "HGNC:12839", "url": "https://alliancegenome.org/gene/HGNC:12839#orthology", "database": "AGR" }, { "id": "RGD:1307372", "url": "https://alliancegenome.org/gene/RGD:1307372#orthology", "database": "AGR" }, { "id": "FB:FBgn0031279", "url": "https://alliancegenome.org/gene/FB:FBgn0031279#orthology", "database": "AGR" }, { "id": "SGD:S000003426", "url": "https://alliancegenome.org/gene/SGD:S000003426#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VEQ0-1", "protein_name": "Xylulose kinase", "gene_name": "Dmel\\CG3534", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGPPKQLKRTFLGFDLSTQKLKAVLLGSSLEVVAAAEVKFDTDLPEFRTTGGANAGSIKNEYFVQPVMWVKAMDIVLDRLVMQQADLSTVAAISGSGQQHGSLYWSKHGINTLQNLDSEKFLHAQIDDSAFVVNRTPIWMDATTTKQCLEMEMAVGGKLNMVELTGSKCYERFTGPQIRKIYQQRCHAYEEANRISLVSSFISSLFLGSVAPIDFSDGSGMNLLDIRKKNWSKECLNVCAPDLDKRLDIPVSPNSILGNVSPYFVERFSFSPDCKVAASTGDNPSALSGMLVGSSWLTISMGTSDTLMMSLKEPLNWEEGHILCHPTETEEFMGLLCFRNASLVREEMNKKTTGGDWDKFNEYLDSTPRGNFGNMAVHFNDMEIIPKAQGILRWNREMDPSSPDAARGVIKFSSPQIEIRALVEGQMLHHRAVAEDLGYKFGPETQILVTGGASVNKSILQTIADVFNAPVHIQDEGFEAALLGAAYRSAYALYLQEAGDGVTPLCYRDYILSLTSNKLSLVCEPHKDSEEIYAPMLQRYREMARVLSNPNT", "length": 552 }, "evidence": [ { "id": "MGI:2142985", "url": "https://alliancegenome.org/gene/MGI:2142985#orthology", "database": "AGR" }, { "id": "HGNC:12839", "url": "https://alliancegenome.org/gene/HGNC:12839#orthology", "database": "AGR" }, { "id": "RGD:1307372", "url": "https://alliancegenome.org/gene/RGD:1307372#orthology", "database": "AGR" }, { "id": "SGD:S000003426", "url": "https://alliancegenome.org/gene/SGD:S000003426#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "xylulose metabolic process", "id": "GO:0005997", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005997", "evidence": [ { "database": "UniProtKB", "id": "Q9VPT2", "url": "https://www.uniprot.org/uniprotkb/Q9VPT2" } ], "pmid": "" }, { "name": "D-xylose metabolic process", "id": "GO:0042732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042732", "evidence": [ { "database": "UniProtKB", "id": "Q9VPT2", "url": "https://www.uniprot.org/uniprotkb/Q9VPT2" } ], "pmid": "" }, { "name": "carbohydrate phosphorylation", "id": "GO:0046835", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046835", "evidence": [ { "database": "UniProtKB", "id": "Q9VPT2", "url": "https://www.uniprot.org/uniprotkb/Q9VPT2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VPT2", "url": "https://www.uniprot.org/uniprotkb/Q9VPT2" } ], "pmid": "" }, { "name": "D-xylulokinase activity", "id": "GO:0004856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004856", "evidence": [ { "database": "UniProtKB", "id": "Q9VPT2", "url": "https://www.uniprot.org/uniprotkb/Q9VPT2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VPT2", "url": "https://www.uniprot.org/uniprotkb/Q9VPT2" } ], "pmid": "" }, { "name": "extracellular exosome", "id": "GO:0070062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070062", "evidence": [ { "database": "UniProtKB", "id": "Q9VPT2", "url": "https://www.uniprot.org/uniprotkb/Q9VPT2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 34, "end_pos": 36, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10964", "name": "", "equation": "D-xylulose + ATP = D-xylulose 5-phosphate + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VEQ0-1", "Q9VPT2-1" ], "evidence": [ { "id": "10964", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10964" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "Q9VEQ0", "gene_name": "Dmel\\CG3534", "activity": [ { "ec_number": "2.7.1.17", "activity": "D-xylulose + ATP = D-xylulose 5-phosphate + ADP + H(+).", "evidence": [ { "id": "Q9VEQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VEQ0" } ] }, { "ec_number": "2.7.1.17", "activity": "", "evidence": [ { "id": "Q9VEQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VEQ0" } ] } ] }, { "uniprot_ac": "Q9VPT2", "gene_name": "Dmel\\CG3544", "activity": [ { "ec_number": "2.7.1.17", "activity": "D-xylulose + ATP = D-xylulose 5-phosphate + ADP + H(+).", "evidence": [ { "id": "Q9VPT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPT2" } ] }, { "ec_number": "2.7.1.17", "activity": "", "evidence": [ { "id": "Q9VPT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPT2" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VPT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPT2" }, { "id": "PF02782", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02782" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Carbohydrate kinase FGGY C-terminal", "eco_id": "ECO_0000259", "start_pos": 301, "end_pos": 494, "start_aa": "Met", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q9VPT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPT2" }, { "id": "PF00370", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00370" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Carbohydrate kinase FGGY N-terminal", "eco_id": "ECO_0000259", "start_pos": 136, "end_pos": 285, "start_aa": "Leu", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.1.17", "ec_name": "D-xylulose + ATP = D-xylulose 5-phosphate + ADP + H(+).", "evidence": [ { "id": "2.7.1.17", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.17" }, { "id": "2.7.1.17", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.1.17" } ] } ], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 538 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 34, "end_pos": 36 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": 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"table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VPT3-1", "uniprot_ac": "Q9VPT3", "uniprot_id": "Q9VPT3_DROME", "mass": { "chemical_mass": 59597.0, "monoisotopic_mass": 59597.0 }, "refseq": { "ac": "NP_608544", "name": "DEAD box protein 21E2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608544" }, "gene_names": [ { "name": "Dbp21E2", "type": "recommended", "evidence": [ { "id": "Q9VPT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPT3" } ] }, { "name": "CG3561", "type": "synonym", "evidence": [ { "id": "NP_608544", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608544" }, { "id": "Q9VPT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPT3" } ] }, { "name": "Dbp21E2", "type": "synonym", "evidence": [ { "id": "NP_608544", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608544" } ] }, { "name": "DmRH9", "type": "synonym", "evidence": [ { "id": "NP_608544", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608544" }, { "id": "Q9VPT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPT3" } ] }, { "name": "Dmel\\CG3561", "type": "synonym", "evidence": [ { "id": "NP_608544", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608544" }, { "id": "Q9VPT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPT3" } ] }, { "name": "Dmel_CG3561", "type": "synonym", "evidence": [ { "id": "Q9VPT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPT3" } ] }, { "name": "KH1", "type": "synonym", "evidence": [ { "id": "NP_608544", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608544" }, { "id": "Q9VPT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPT3" } ] }, { "name": "cg3561", "type": "synonym", "evidence": [ { "id": "NP_608544", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608544" }, { "id": "Q9VPT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPT3" } ] } ], "protein_names": [ { "name": "3.6.4.13", "type": "synonym", "evidence": [ { "id": "Q9VPT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPT3/entry#names_and_taxonomy" } ] }, { "name": "CG3561-PA", "type": "synonym", "evidence": [ { "id": "NP_608544", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608544" } ] }, { "name": "DEAD box protein 21E2", "type": "synonym", "evidence": [ { "id": "NP_608544", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608544" }, { "id": "Q9VPT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPT3/entry#names_and_taxonomy" } ] }, { "name": "Dbp21E2-PA", "type": "synonym", "evidence": [ { "id": "NP_608544", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608544" } ] }, { "name": "KH1", "type": "synonym", "evidence": [ { "id": "NP_608544", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608544" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VPT3", "url": "https://www.uniprot.org/uniprotkb/Q9VPT3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dbp21E2", "url": "https://www.uniprot.org/uniprotkb/Q9VPT3", "locus": { "chromosome": "2L", "start_pos": 813380, "end_pos": 811584, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0086130", "url": "https://www.ensemblgenomes.org/id/FBgn0086130" } ] } } ], "crossref": [ { "id": "FB:FBgn0086130", "url": "https://alliancegenome.org/gene/FB:FBgn0086130", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0086130", "url": "https://bgee.org/?page=gene&gene_id=FBgn0086130", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17948", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17948", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18787", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18787", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0086130", "url": "https://flybase.org/reports/FBgn0086130", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "33254", "url": "https://www.ncbi.nlm.nih.gov/gene/33254", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VPT3", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VPT3*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR001650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011545", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011545", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG3561", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3561", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NGDMLMK", "url": "https://omabrowser.org/oma/group/NGDMLMK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VPT3", "url": "https://www.orthodb.org/?gene=Q9VPT3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47960", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47960", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00270", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00270", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q9VPT3", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q9VPT3", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_608544", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608544", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VPT3", "url": "https://www.uniprot.org/uniprotkb/Q9VPT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VPT3-1", "url": "https://www.uniprot.org/uniprotkb/Q9VPT3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLNLSVVLRVQSSRHVASYATAAAAAVKTKPPKAKSKGKKQKGEPLISCRRSQFDLTQYEQTDAKFGSLSLASKGWLHNKSKGDFFILNASVRGEELQQEMQTVDEFLESTGMQIHPQLLENLRVELGIKLLTGIQKQGMPVVHGNEHCLIAAETGCGKTITYLLPIVDKLLQKEVVTERKLNTPRVLILTPGRELATQIAGVTEKLTQGTNLKVQSLLGGNTKQLMMNPQFEEVDILVATLGALSKLVTTGIYRMEQVRHLVLDEADTLLDDTFTDKLSYFLRRFPFHLVQKEDAGTQMILASATMPTNTREILHKVIDVDTIREVVSPHLHRLMSHVTQKFLRLSKADRPATLLSLVKHDLAKRRPLIVFSNKSTTSDFVSIFLNNSGVNCLNLNGDMLMKIRLGRFEQFQNGHCDVLSTTDVGSRGLDTTRARHVVNFDFPLHVSDYIHRCGRIGRVGNMDKALVTNLISSRREIDVVQRIEHAARTGGLLPDVNANIRNIINKRIVAEMKAAGMPVPALGSLNGHTPQEEAF", "length": 536, "header": "tr|Q9VPT3-1|Q9VPT3_DROME Isoform 1 of DEAD box protein 21E2 OS=Drosophila melanogaster OX=7227 GN=Dbp21E2 PE=1 SV=1 CANONICAL=Q9VPT3-1" }, "isoforms": [ { "isoform_ac": "Q9VPT3-1", "url": "https://www.uniprot.org/uniprotkb/Q9VPT3/entry#Q9VPT3-1", "sequence": { "sequence": "MLNLSVVLRVQSSRHVASYATAAAAAVKTKPPKAKSKGKKQKGEPLISCRRSQFDLTQYEQTDAKFGSLSLASKGWLHNKSKGDFFILNASVRGEELQQEMQTVDEFLESTGMQIHPQLLENLRVELGIKLLTGIQKQGMPVVHGNEHCLIAAETGCGKTITYLLPIVDKLLQKEVVTERKLNTPRVLILTPGRELATQIAGVTEKLTQGTNLKVQSLLGGNTKQLMMNPQFEEVDILVATLGALSKLVTTGIYRMEQVRHLVLDEADTLLDDTFTDKLSYFLRRFPFHLVQKEDAGTQMILASATMPTNTREILHKVIDVDTIREVVSPHLHRLMSHVTQKFLRLSKADRPATLLSLVKHDLAKRRPLIVFSNKSTTSDFVSIFLNNSGVNCLNLNGDMLMKIRLGRFEQFQNGHCDVLSTTDVGSRGLDTTRARHVVNFDFPLHVSDYIHRCGRIGRVGNMDKALVTNLISSRREIDVVQRIEHAARTGGLLPDVNANIRNIINKRIVAEMKAAGMPVPALGSLNGHTPQEEAF", "length": 536, "header": "tr|Q9VPT3-1|Q9VPT3_DROME Isoform 1 of DEAD box protein 21E2 OS=Drosophila melanogaster OX=7227 GN=Dbp21E2 PE=1 SV=1 CANONICAL=Q9VPT3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VPT3", "url": "https://www.uniprot.org/uniprotkb/Q9VPT3" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VPT3", "url": "https://www.uniprot.org/uniprotkb/Q9VPT3" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPT3", "url": "https://www.uniprot.org/uniprotkb/Q9VPT3" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPT3", "url": "https://www.uniprot.org/uniprotkb/Q9VPT3" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VPT3", "url": "https://www.uniprot.org/uniprotkb/Q9VPT3" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VPT3", "url": "https://www.uniprot.org/uniprotkb/Q9VPT3" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VPT3", "url": "https://www.uniprot.org/uniprotkb/Q9VPT3" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPT3", "url": "https://www.uniprot.org/uniprotkb/Q9VPT3" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPT3", "url": "https://www.uniprot.org/uniprotkb/Q9VPT3" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VPT3", "url": "https://www.uniprot.org/uniprotkb/Q9VPT3" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VPT3", "url": "https://www.uniprot.org/uniprotkb/Q9VPT3" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG3561", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3561", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1A4K4-1", "protein_name": "RNA helicase", "gene_name": "DDX28", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVLRRGAVAAARAASAQPPENVVRIPWALRLRLQRGERGRRCGQGQTAAVWSGKLLLRSRRPELSQPRWQTVGRWERPQLVSAGWKHRKARGDYFQLEAVQEMAPALQAPQHQEERGPLFAEMGLQSALLTALQDLSIARPTAVQRLAIPALRRGRSALCAAETGSGKTLAYLLPLLDRLLARPPGPEPAVEKPEGSGPRSASPCGLVVLPSRELVAQVGTVAAALCRPAGLLVRGLTGGGAAGGLRRQLRAPPPGATVLLGTPGALRTALRRRFVVLGRLRWVVLDEADTLIDDESFATPLEEVLAHAPLAAGAPGPAGPGEERTQVVVVGATFPAGLSQMLARFVDVDCFVNLSTQSLHHLPSHVQQKFVCLKGQDKLPELLQLLKERSASSGAVLIFCNSASTVNWLGYILDDHKIKHLRLQGQMMAAMRAGIFASFQKGDVSVLICTDLASRGLDTSSVQLVVNYDFPNTLQDYLHRVGRVGRVGSKMPGAVVSFVTHRWDVDLVRKIETAARKRAGLPGMDASINEPPPKAD", "length": 537 }, "evidence": [ { "id": "Q9VPT3", "url": "https://omabrowser.org/oma/group/Q9VPT3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4A7Q5-1", "protein_name": "Probable ATP-dependent RNA helicase DDX28", "gene_name": "Ddx28", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLFCIKRNMALAGPTRLLSLAVRLLLEPRRNIVLRGSDQSLPVVRIPRALQRRQEQRRSDRGSFQRPVLVQPGPLLVSAKRPELNQPARLTLGRWERAPLASRGWKHRRSRQDHFSIERVQQEAPAMRNLSSRGNFVDLGLEPRVLLALQKAVPEIVQPTSVQSKTIPPLLRGRHILCAAETGSGKTLSYLLPLFQRLLKGPELDSRSSTAPRGLVLVPSRELAEQVQAVAQSLGRYLDLQVIELGGGLGMNRLKLQLGKWPSADVLVATPGALWKALKSQLISLHHLNFIVLDEVDTLLDESFVELVDYILGKSPIAESPAELEDPFNPKAQLVMVGATFPEGLNQLLSKVTSPDSLTTITSSKLHCIMPHVRQTFMRLKGTEKVTELIQILKQHDKANKAEPSGTVLVFCNSASTVNWLGYILDDHKIQHLRLQGQMPASMRAGIFQSFQKGSQNILVCTDIASRGLDSIHVEMVVNYDFPPTLQDYIHRAGRVGRVGSEVPGTVTSFVTHPWDVSLVQKIELAARRRRSLPGLTSSVRDPLPQQD", "length": 549 }, "evidence": [ { "id": "MGI:1919236", "url": "https://alliancegenome.org/gene/MGI:1919236#orthology", "database": "AGR" }, { "id": "HGNC:17330", "url": "https://alliancegenome.org/gene/HGNC:17330#orthology", "database": "AGR" }, { "id": "FB:FBgn0086130", "url": "https://alliancegenome.org/gene/FB:FBgn0086130#orthology", "database": "AGR" }, { "id": "RGD:1311976", "url": "https://alliancegenome.org/gene/RGD:1311976#orthology", "database": "AGR" }, { "id": "SGD:S000003032", "url": "https://alliancegenome.org/gene/SGD:S000003032#orthology", "database": "AGR" }, { "id": "Q9VPT3", "url": "https://omabrowser.org/oma/group/Q9VPT3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3LB32-1", "protein_name": "RNA helicase", "gene_name": "DDX28", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MALARQLRLLSLVTRLHLAPRRDLTVRGPDEPLPVVRIPRALQRRQEQRQRGQQGPPRPVLVRPGQLLISARRPELNQPARLTLGRWEPAPLASRGWKNRRARQDHFSIERKQQEAPALRNLSSKDSFADLGLEPRVLSALQEAAPEVVRPTTVQSSTIPPLLGGRHILCAAETGSGKTLGYMLPLLQRLLGQPSLDSCRIPAPRGLVLVPSRELAEQVRAVAQPLGSSLGLQVRELGGGHGMSRIRLQLSKQPPADVLVATPGALWKGLKSQLISLEQLSFLVLDEADTLLDESFLELVDYILEKSHIAEGPADLKDPFNPKAQLVLVGATFPEGVSQLLSKAACLDSLTTITSSKLHCIMPHVKQTFMRLKGAEKVTELVQILKQHDRAYRTGSAGTVLVFCNSSSTVNWLGYILDDHKIQHLRLQGQMPASMRAGIFQSFQRGSQDILLCTDIASRGLDSTQVELVINYDFPLTLQDYIHRAGRVGRVGSKVPGTVISFVTHPWDVSLVQKIELAARRRRSLPGLGSSVREPLPQQT", "length": 540 }, "evidence": [ { "id": "Q9VPT3", "url": "https://omabrowser.org/oma/group/Q9VPT3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P53166-1", "protein_name": "ATP-dependent RNA helicase MRH4, mitochondrial", "gene_name": "MRH4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSLFFKPVISPQWSFPVLLKIGVRSYAGGPRTKHKGNSPLASVPTGSSNKNRKQKAKGKKGNKKNDPDQAFNFGEYGGLKKDVEMNMDSTNKLIQKISNFDQLLILPPVRDAVKEIISKESLKLQDSRKKTSENIIPSPIQTVAIKRISKNLMDPKLQIHAIAAETGSGKTMAYLIPLIDYLKRQELETPELWETLRKNVLIRSIILVPTHELVDQVYETVSKTKTLLGLNSFKWDKATSYRDLLENIKNRIDILVTTPGKLLNLFSIRMITRPDKVLSKVGFVVLDEADTLLDRSWLEETHSAIKRIPNINHLIFCSATIPQEFNKTMQRLFPTVVPIMTPRLHKLPFALDFKVINSALSPFKGSKIKALAQTLYAISNDDTEPGFEKRCIIFVNEKKNVPEIVNLLNKKFGHNAIGLTGEDTFEERSEKIMPFLSPPRPLSEVVAQSTSPPTSLKKFEIPDSNIVIGKLKNTNSNGTAPSNKSLHVLVTTDLMARGLNFKGVRNVVLYDVPKTSIDLIHRVGRTARMKQGGRVFMLTDSKTKSWAKALPKIIKKHQRLS", "length": 561 }, "evidence": [ { "id": "MGI:1919236", "url": "https://alliancegenome.org/gene/MGI:1919236#orthology", "database": "AGR" }, { "id": "HGNC:17330", "url": "https://alliancegenome.org/gene/HGNC:17330#orthology", "database": "AGR" }, { "id": "FB:FBgn0086130", "url": "https://alliancegenome.org/gene/FB:FBgn0086130#orthology", "database": "AGR" }, { "id": "RGD:1311976", "url": "https://alliancegenome.org/gene/RGD:1311976#orthology", "database": "AGR" }, { "id": "SGD:S000003032", "url": "https://alliancegenome.org/gene/SGD:S000003032#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q9CWT6-1", "protein_name": "Probable ATP-dependent RNA helicase DDX28", "gene_name": "Ddx28", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALAGPSRLLALAVRLLLEPRRNLVVRGSDQSLPVVRVPRALQRRQEQRQSGRGSLQRPVLVRPGPLLVSARRPELNQPARLTLGRWERAPLASRGWKHRRSRQDHFSIERVQQEAPALRNLSSRGSFVDLGLEPRVLLALQEAVPEVVQPTSVQSKTIPPLLRGRHLLCAAETGSGKTLSYLLPLFQRLLRGSDLDSRSFTAPRGLVLVPSRELAEQVQAVAQSLGGYLGLQVIELGGGLGMSRLKLQLYRRPAADVLVATPGALWKALKSQLISLQHLNFIVLDEVDTLLDESFLELVDYILEKSPIAESPAELEDPFNPKAQLVLVGATFPEGLNQLLSKVTSPDSLTTITSSKLHCLMPHVRQTFMRLKGADKVTELVQILKQQDKASKTEPSGTVLVFCNSASTVNWLGYILDDHKIQHLRLQGQMPASMRAGIFQSFQKGSQNILVCTDIASRGLDSVHVEVVINYDFPPTLQDYIHRAGRVGRVGSEVPGSVISFVTHPWDVSLVQKIELAARRRRSLPGLASSVGDPLPQKA", "length": 540 }, "evidence": [ { "id": "MGI:1919236", "url": "https://alliancegenome.org/gene/MGI:1919236#orthology", "database": "AGR" }, { "id": "HGNC:17330", "url": "https://alliancegenome.org/gene/HGNC:17330#orthology", "database": "AGR" }, { "id": "FB:FBgn0086130", "url": "https://alliancegenome.org/gene/FB:FBgn0086130#orthology", "database": "AGR" }, { "id": "RGD:1311976", "url": "https://alliancegenome.org/gene/RGD:1311976#orthology", "database": "AGR" }, { "id": "SGD:S000003032", "url": "https://alliancegenome.org/gene/SGD:S000003032#orthology", "database": "AGR" }, { "id": "Q9VPT3", "url": "https://omabrowser.org/oma/group/Q9VPT3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NUL7-1", "protein_name": "Probable ATP-dependent RNA helicase DDX28", "gene_name": "DDX28", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALTRPVRLFSLVTRLLLAPRRGLTVRSPDEPLPVVRIPVALQRQLEQRQSRRRNLPRPVLVRPGPLLVSARRPELNQPARLTLGRWERAPLASQGWKSRRARRDHFSIERAQQEAPAVRKLSSKGSFADLGLEPRVLHALQEAAPEVVQPTTVQSSTIPSLLRGRHVVCAAETGSGKTLSYLLPLLQRLLGQPSLDSLPIPAPRGLVLVPSRELAQQVRAVAQPLGRSLGLLVRDLEGGHGMRRIRLQLSRQPSADVLVATPGALWKALKSRLISLEQLSFLVLDEADTLLDESFLELVDYILEKSHIAEGPADLEDPFNPKAQLVLVGATFPEGVGQLLNKVASPDAVTTITSSKLHCIMPHVKQTFLRLKGADKVAELVHILKHRDRAERTGPSGTVLVFCNSSSTVNWLGYILDDHKIQHLRLQGQMPALMRVGIFQSFQKSSRDILLCTDIASRGLDSTGVELVVNYDFPPTLQDYIHRAGRVGRVGSEVPGTVISFVTHPWDVSLVQKIELAARRRRSLPGLASSVKEPLPQAT", "length": 540 }, "evidence": [ { "id": "MGI:1919236", "url": "https://alliancegenome.org/gene/MGI:1919236#orthology", "database": "AGR" }, { "id": "HGNC:17330", "url": "https://alliancegenome.org/gene/HGNC:17330#orthology", "database": "AGR" }, { "id": "FB:FBgn0086130", "url": "https://alliancegenome.org/gene/FB:FBgn0086130#orthology", "database": "AGR" }, { "id": "RGD:1311976", "url": "https://alliancegenome.org/gene/RGD:1311976#orthology", "database": "AGR" }, { "id": "SGD:S000003032", "url": "https://alliancegenome.org/gene/SGD:S000003032#orthology", "database": "AGR" }, { "id": "Q9VPT3", "url": "https://omabrowser.org/oma/group/Q9VPT3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VPT3", "url": "https://www.uniprot.org/uniprotkb/Q9VPT3" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "Q9VPT3", "url": "https://www.uniprot.org/uniprotkb/Q9VPT3" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "Q9VPT3", "url": "https://www.uniprot.org/uniprotkb/Q9VPT3" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "Q9VPT3", "url": "https://www.uniprot.org/uniprotkb/Q9VPT3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VPT3", "url": "https://www.uniprot.org/uniprotkb/Q9VPT3" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9VPT3", "url": "https://www.uniprot.org/uniprotkb/Q9VPT3" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "Q9VPT3", "url": "https://www.uniprot.org/uniprotkb/Q9VPT3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mitochondrial large ribosomal subunit assembly", "id": "GO:1902775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902775", "evidence": [ { "database": "UniProtKB", "id": "Q9VPT3", "url": "https://www.uniprot.org/uniprotkb/Q9VPT3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 374, "end_pos": 376, "annotation": "n_glycosylation_sequon" }, { "start_pos": 387, "end_pos": 389, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" }, { "start_pos": 79, "end_pos": 81, "annotation": "n_glycosylation_sequon" }, { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VPT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPT3" }, { "id": "PS51192", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51192" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Helicase ATP-binding", "eco_id": "ECO_0000259", "start_pos": 140, "end_pos": 325, "start_aa": "Met", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q9VPT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPT3" }, { "id": "PS51194", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51194" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Helicase C-terminal", "eco_id": "ECO_0000259", "start_pos": 358, "end_pos": 505, "start_aa": "Leu", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.6.4.13", "ec_name": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "3.6.4.13", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13" }, { "id": "3.6.4.13", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.6.4.13" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 374, "end_pos": 376 }, { "start_pos": 387, "end_pos": 389 }, { "start_pos": 3, "end_pos": 5 }, { "start_pos": 79, "end_pos": 81 }, { "start_pos": 89, "end_pos": 91 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VPU5-1", "uniprot_ac": "Q9VPU5", "uniprot_id": "Q9VPU5_DROME", "mass": { "chemical_mass": 16838.0, "monoisotopic_mass": 16838.0 }, "refseq": { "ac": "NP_001259848", "name": "uncharacterized protein, isoform B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259848" }, "gene_names": [ { "name": "Dmel\\CG13949", "type": "recommended", "evidence": [ { "id": "Q9VPU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPU5" } ] }, { "name": "BcDNA:AT06839", "type": "synonym", "evidence": [ { "id": "NP_001259848", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259848" }, { "id": "Q9VPU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPU5" } ] }, { "name": "CG13949", "type": "synonym", "evidence": [ { "id": "NP_001259848", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259848" }, { "id": "Q9VPU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPU5" } ] }, { "name": "Dmel\\CG13949", "type": "synonym", "evidence": [ { "id": "NP_001259848", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259848" } ] }, { "name": "Dmel_CG13949", "type": "synonym", "evidence": [ { "id": "Q9VPU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPU5" } ] } ], "protein_names": [ { "name": "CG13949-PB", "type": "synonym", "evidence": [ { "id": "NP_001259848", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259848" } ] }, { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "Q9VPU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPU5/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein, isoform B", "type": "synonym", "evidence": [ { "id": "NP_001259848", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259848" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VPU5", "url": "https://www.uniprot.org/uniprotkb/Q9VPU5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG13949", "url": "https://www.uniprot.org/uniprotkb/Q9VPU5", "locus": { "chromosome": "2L", "start_pos": 856639, "end_pos": 855337, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0031288", "url": "https://www.ensemblgenomes.org/id/FBgn0031288" } ] } } ], "crossref": [ { "id": "FB:FBgn0031288", "url": "https://alliancegenome.org/gene/FB:FBgn0031288", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0031288", "url": "https://bgee.org/?page=gene&gene_id=FBgn0031288", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0031288", "url": "https://flybase.org/reports/FBgn0031288", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "33266", "url": "https://www.ncbi.nlm.nih.gov/gene/33266", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VPU5", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VPU5*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "dme:Dmel_CG13949", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG13949", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YDLIMHD", "url": "https://omabrowser.org/oma/group/YDLIMHD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VPU5", "url": "https://www.orthodb.org/?gene=Q9VPU5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "NP_001259848", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259848", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VPU5", "url": "https://www.uniprot.org/uniprotkb/Q9VPU5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VPU5-1", "url": "https://www.uniprot.org/uniprotkb/Q9VPU5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDLIKEINDKYMALEAEIDQKLEKVQAEELKLERQNEQLAESSICAPAPKVLSYEEALLRNTNTLKALEIAKARLRSRSTYSPVEKLLQQALQNYRRELESLQDAEDRGKDPKNPDNQEEEGEEENLYDLVMQNVMEAKRQQTDL", "length": 145, "header": "tr|Q9VPU5-1|Q9VPU5_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG13949 PE=4 SV=1 CANONICAL=Q9VPU5-1" }, "isoforms": [ { "isoform_ac": "Q9VPU5-1", "url": "https://www.uniprot.org/uniprotkb/Q9VPU5/entry#Q9VPU5-1", "sequence": { "sequence": "MDLIKEINDKYMALEAEIDQKLEKVQAEELKLERQNEQLAESSICAPAPKVLSYEEALLRNTNTLKALEIAKARLRSRSTYSPVEKLLQQALQNYRRELESLQDAEDRGKDPKNPDNQEEEGEEENLYDLVMQNVMEAKRQQTDL", "length": 145, "header": "tr|Q9VPU5-1|Q9VPU5_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG13949 PE=4 SV=1 CANONICAL=Q9VPU5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VPU5", "url": "https://www.uniprot.org/uniprotkb/Q9VPU5" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VPU5", "url": "https://www.uniprot.org/uniprotkb/Q9VPU5" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPU5", "url": "https://www.uniprot.org/uniprotkb/Q9VPU5" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPU5", "url": "https://www.uniprot.org/uniprotkb/Q9VPU5" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VPU5", "url": "https://www.uniprot.org/uniprotkb/Q9VPU5" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VPU5", "url": "https://www.uniprot.org/uniprotkb/Q9VPU5" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VPU5", "url": "https://www.uniprot.org/uniprotkb/Q9VPU5" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPU5", "url": "https://www.uniprot.org/uniprotkb/Q9VPU5" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPU5", "url": "https://www.uniprot.org/uniprotkb/Q9VPU5" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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{ "name": "mtRNA-pol", "type": "synonym", "evidence": [ { "id": "NP_001259853", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259853" }, { "id": "Q9VPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPW4" } ] }, { "name": "mtRNAPol", "type": "synonym", "evidence": [ { "id": "NP_001259853", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259853" }, { "id": "Q9VPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPW4" } ] }, { "name": "mtRNAP", "type": "synonym", "evidence": [ { "id": "NP_001259853", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259853" }, { "id": "Q9VPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPW4" } ] }, { "name": "mtRNApol", "type": "synonym", "evidence": [ { "id": "NP_001259853", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259853" }, { "id": "Q9VPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPW4" } ] } ], "protein_names": [ { "name": "DNA-directed RNA polymerase", "type": "recommended", "evidence": [ { "id": "Q9VPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPW4/entry#names_and_taxonomy" } ] }, { "name": "2.7.7.6", "type": "synonym", "evidence": [ { "id": "Q9VPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPW4/entry#names_and_taxonomy" } ] }, { "name": "CG4644-PB", "type": "synonym", "evidence": [ { "id": "NP_001259853", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259853" } ] }, { "name": "PolrMT-PB", "type": "synonym", "evidence": [ { "id": "NP_001259853", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259853" } ] }, { "name": "RNA polymerase mitochondrial, isoform B", "type": "synonym", "evidence": [ { "id": "NP_001259853", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259853" } ] }, { "name": "mitochondrial RNA polymerase", "type": "synonym", "evidence": [ { "id": "NP_001259853", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259853" } ] } ], "function": [ { "annotation": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW4", "url": "https://www.uniprot.org/uniprotkb/Q9VPW4#function" }, { "database": "UniProtKB", "id": "RU003805", "url": "https://www.uniprot.org/uniprotkb/RU003805#function" } ] }, { "annotation": "DNA-dependent RNA polymerase catalyzes the transcription of mitochondrial DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of the mitochondrial transcription initiation complex, composed at least of TFB2M, TFAM and POLRMT that is required for basal transcription of mitochondrial DNA. In this complex, TFAM recruits POLRMT to a specific promoter whereas TFB2M induces structural changes in POLRMT to enable promoter opening and trapping of the DNA non-template strand. Has DNA primase activity. Catalyzes the synthesis of short RNA primers that are necessary for the initiation of lagging-strand DNA synthesis from the origin of light-strand DNA replication (OriL).", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW4", "url": "https://www.uniprot.org/uniprotkb/Q9VPW4#function" }, { "database": "UniProtKB", "id": "ARBA00057821", "url": "https://www.uniprot.org/uniprotkb/ARBA00057821#function" } ] } ], "disease": [ { "disease_id": "DOID:0070428", "recommended_name": { "id": "DOID:0070428", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070428", "name": "combined oxidative phosphorylation deficiency 55", "description": "A combined oxidative phosphorylation deficiency that has_material_basis_in homozygous, compound heterozygous, or heterozygous mutation in the POLRMT gene on chromosome 19p13." }, "synonyms": [ { "id": "DOID:0070428", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070428", "name": "COXPD55", "description": "" }, { "id": "MONDO:0859228", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0859228", "name": "combined oxidative phosphorylation deficiency 55", "description": "" }, { "id": "MIM:619743", "resource": "MIM", "url": "https://www.omim.org/entry/619743", "name": "Combined oxidative phosphorylation deficiency 55", "description": "Combined oxidative phosphorylation deficiency 55" } ], "unlinked_id_list": [], "evidence": [ { "id": "0070428", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070428" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VPW4", "url": "https://www.uniprot.org/uniprotkb/Q9VPW4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "PolrMT", "url": "https://www.uniprot.org/uniprotkb/Q9VPW4", "locus": { "chromosome": "2L", "start_pos": 1103254, "end_pos": 1108373, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0261938", "url": "https://www.ensemblgenomes.org/id/FBgn0261938" } ] } } ], "crossref": [ { "id": "FB:FBgn0261938", "url": "https://alliancegenome.org/gene/FB:FBgn0261938", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0261938", "url": "https://bgee.org/?page=gene&gene_id=FBgn0261938", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0261938", "url": "https://flybase.org/reports/FBgn0261938", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "33285", "url": "https://www.ncbi.nlm.nih.gov/gene/33285", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VPW4", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VPW4*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR002092", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002092", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002885", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002885", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029262", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029262", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046950", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046950", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG4644", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG4644", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WWAKSDE", "url": "https://omabrowser.org/oma/group/WWAKSDE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VPW4", "url": "https://www.orthodb.org/?gene=Q9VPW4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10102", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10102", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10102:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10102:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00940", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00940", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14700", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14700", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-163282", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-163282", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-9913635", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9913635", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001259853", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259853", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "21248", "url": "https://www.rhea-db.org/rhea/21248", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q9VPW4", "url": "https://www.uniprot.org/uniprotkb/Q9VPW4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VPW4-1", "url": "https://www.uniprot.org/uniprotkb/Q9VPW4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYRLLSANRAAAVQKALRVPPTAHPTTTTATTTTVCCGCGIAPSNFVHYQQYYQMLYRQMPAGAITAKTTTTTTRTQTTTPTQTDAVAQAKKKRLRKPRYAKYVELLEVTEQAISERRSRVKRLKSKKLADFIHKAQQQILERRAREDRKDKKTKCVLDLAQRQPVEYQKIDMEALDGSILESGVYDDRPMLFFGKDEYTKQVIANPEEVQNILKSFQNFRDIIESMENDQHEADFGLSTTKVHPEEHEMLDPFEAIEPYISPLDKSKRSVTTVAVPNASAVTTKSKKRFKSKVHVNEEQERLAKQRALHINLNTYLNVCVSANMLNRALSTIIAYRGKVRKSSLPHMSEGLITIDLYNILLHGYAGKGSFDRAQEVFKLIEEDGLSFNEQTYAAIFECLGRLEPDEENHQYISEYVSKAEKEGFSLNQIMDRSKFVADQRDIALDAIRRLRPDFKPVYVPPQLGYDNELLDHLNEHVIPVGAKKEPGKADYAIMNSKRGYTAAQLEQLAREQLKIELDGSITIKSIEKSKEFANSEKCRELLKELEDTWRKQISAAIVRDLNTLRAQVRFKPHGFMNYYTYLKTLDASHFADILIKELYKLAEGSETFSPTVGQLYKELGQKVQQRYQIEQKKHNGTLEKIGEIYSSYCELWGSGMSQDNTRQAWQRLVYEQRESGPSMDLLEVPWPSNVLTGVGRFLYNILMRDIKIDAHIMRQKSKSKAAAQPQNLLPAFYTLFRNQGRFVKEEVKPHPVLSRLFRASRQQTLTFDSNLVPMLCPPQPWSTPHNGGYLLNKTELIRLPHQAIQQWDRIMASNPQHLYPALDSLNQLASVPWRVNTQLLDVIIKVFQNGGDVKLDVPQPPSSLPPLPTLPAKDAEGNATSSEDRAKQFRDKLGHRRKQAEMYSLWCDALYRLSLAQHYRDKVFWLPHNMDFRGRVYPVPPHLNHLGSDLARSMLIFDQAQPLGVDGLSWLKLHCINLTGLKKRDSVRERLLYAEEIMPDILDSADNPLTGRMWWSKSDEPWQTLACCMEIANVHRCPDPAAYLSRFPIHQDGSCNGLQHYAALGRDEAGARSVNLAPSAIPQDVYSAVAALVEKSRKADAQNGLHVAEALAGFVRRKVIKQTVMTTVYGVTRYGARLQIARQLKDIDDFPKDWVWPASTYLTTKTFESLREMFTSTREIQDWFTECARLISGVCSQNVEWVTPLGLPVVQPYNRQEMKHSPRSGFKVSANMPMDLYERPNILKQKNAFPPNFIHSLDSSHMMLTSLHCERQGITFVSVHDCFWTHANTVPELNRMCREQFVALHSQPILEQLSEFMRHTYSFKDSDFINDGSVEDLSKRQLNRILKQMPQKGDFDLRNVLDSVYFFS", "length": 1369, "header": "tr|Q9VPW4-1|Q9VPW4_DROME Isoform 1 of DNA-directed RNA polymerase OS=Drosophila melanogaster OX=7227 GN=PolrMT PE=3 SV=1 CANONICAL=Q9VPW4-1" }, "isoforms": [ { "isoform_ac": "Q9VPW4-1", "url": "https://www.uniprot.org/uniprotkb/Q9VPW4/entry#Q9VPW4-1", "sequence": { "sequence": "MYRLLSANRAAAVQKALRVPPTAHPTTTTATTTTVCCGCGIAPSNFVHYQQYYQMLYRQMPAGAITAKTTTTTTRTQTTTPTQTDAVAQAKKKRLRKPRYAKYVELLEVTEQAISERRSRVKRLKSKKLADFIHKAQQQILERRAREDRKDKKTKCVLDLAQRQPVEYQKIDMEALDGSILESGVYDDRPMLFFGKDEYTKQVIANPEEVQNILKSFQNFRDIIESMENDQHEADFGLSTTKVHPEEHEMLDPFEAIEPYISPLDKSKRSVTTVAVPNASAVTTKSKKRFKSKVHVNEEQERLAKQRALHINLNTYLNVCVSANMLNRALSTIIAYRGKVRKSSLPHMSEGLITIDLYNILLHGYAGKGSFDRAQEVFKLIEEDGLSFNEQTYAAIFECLGRLEPDEENHQYISEYVSKAEKEGFSLNQIMDRSKFVADQRDIALDAIRRLRPDFKPVYVPPQLGYDNELLDHLNEHVIPVGAKKEPGKADYAIMNSKRGYTAAQLEQLAREQLKIELDGSITIKSIEKSKEFANSEKCRELLKELEDTWRKQISAAIVRDLNTLRAQVRFKPHGFMNYYTYLKTLDASHFADILIKELYKLAEGSETFSPTVGQLYKELGQKVQQRYQIEQKKHNGTLEKIGEIYSSYCELWGSGMSQDNTRQAWQRLVYEQRESGPSMDLLEVPWPSNVLTGVGRFLYNILMRDIKIDAHIMRQKSKSKAAAQPQNLLPAFYTLFRNQGRFVKEEVKPHPVLSRLFRASRQQTLTFDSNLVPMLCPPQPWSTPHNGGYLLNKTELIRLPHQAIQQWDRIMASNPQHLYPALDSLNQLASVPWRVNTQLLDVIIKVFQNGGDVKLDVPQPPSSLPPLPTLPAKDAEGNATSSEDRAKQFRDKLGHRRKQAEMYSLWCDALYRLSLAQHYRDKVFWLPHNMDFRGRVYPVPPHLNHLGSDLARSMLIFDQAQPLGVDGLSWLKLHCINLTGLKKRDSVRERLLYAEEIMPDILDSADNPLTGRMWWSKSDEPWQTLACCMEIANVHRCPDPAAYLSRFPIHQDGSCNGLQHYAALGRDEAGARSVNLAPSAIPQDVYSAVAALVEKSRKADAQNGLHVAEALAGFVRRKVIKQTVMTTVYGVTRYGARLQIARQLKDIDDFPKDWVWPASTYLTTKTFESLREMFTSTREIQDWFTECARLISGVCSQNVEWVTPLGLPVVQPYNRQEMKHSPRSGFKVSANMPMDLYERPNILKQKNAFPPNFIHSLDSSHMMLTSLHCERQGITFVSVHDCFWTHANTVPELNRMCREQFVALHSQPILEQLSEFMRHTYSFKDSDFINDGSVEDLSKRQLNRILKQMPQKGDFDLRNVLDSVYFFS", "length": 1369, "header": "tr|Q9VPW4-1|Q9VPW4_DROME Isoform 1 of DNA-directed RNA polymerase OS=Drosophila melanogaster OX=7227 GN=PolrMT PE=3 SV=1 CANONICAL=Q9VPW4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 612, "start_aa": "Thr", "end_pos": 612, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr612", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW4", "url": "https://www.uniprot.org/uniprotkb/Q9VPW4" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW4", "url": "https://www.uniprot.org/uniprotkb/Q9VPW4" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW4", "url": "https://www.uniprot.org/uniprotkb/Q9VPW4" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW4", "url": "https://www.uniprot.org/uniprotkb/Q9VPW4" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW4", "url": "https://www.uniprot.org/uniprotkb/Q9VPW4" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW4", "url": "https://www.uniprot.org/uniprotkb/Q9VPW4" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW4", "url": "https://www.uniprot.org/uniprotkb/Q9VPW4" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW4", "url": "https://www.uniprot.org/uniprotkb/Q9VPW4" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW4", "url": "https://www.uniprot.org/uniprotkb/Q9VPW4" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW4", "url": "https://www.uniprot.org/uniprotkb/Q9VPW4" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW4", "url": "https://www.uniprot.org/uniprotkb/Q9VPW4" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG4644", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG4644", "resource": "KEGG Pathway" }, { "id": "R-DME-163282", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-163282", "resource": "Reactome", "description": "Mitochondrial transcription initiation" }, { "id": "R-DME-9913635", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9913635", "resource": "Reactome", "description": "Strand-asynchronous mitochondrial DNA replication" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5Y8F7-1", "protein_name": "DNA-directed RNA polymerase", "gene_name": "Polrmt", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSALRWTRGAAGLGRVLRSPGPHRPASEEGPLSGLGSSRRRSAASPREQAVQREWGHAELLEVLEARVRQLRAEGAPEMRVKKVQVDQPPQGRSSRWAQKLEAEKKVKQRHQAKADLQKQPLESRTLHTEPRIRSKKLAGYLHQSKKGAPKSSEEEQLARVLQAVLAKLGSREAGTPARTKAKAVETHILFLQQKLRTFFECCVCTGQLPLAHHMLVTHHNNQDKQQVLTLDMYNMVLLGWARKGSFRELVYVFIMLTDAGLSPDLHSYAAALQCMGRRDQDAHTIQRCLKQMAEEGFQPQLLFTNLVLEEEDRAALLRAVVKGEPAFCPPPQASNLVSTPVLLKDFYSKEGPVSYPKLHLPLDTLQDLFYQQLHVELSSSVSVQSVEEAPVMTKEVIEARKTLKALRSKWEVELLRVLRETKAKMGSQAYEGQPTLYPFLCLLSEGEFVSILMQALQVLPAQGEPLFQLAQNLGLQVFNRHLVKQKQVTNHVQKLGQQYSQYLRLLASDTQVAPCLPREYWDSLGSLETPAQQPWSVPVLLQLGKQLAELLVQAVQMPRSLAARHGAQNFIPVLYHVYSFRSYRQVGILKPHPAFTHLLETAAEPTLTFETTEVPMLCPPLPWTSLHSGAYLLSSTKIMRATEGTTQHQRLLERCPPAQLHGALDALTQLGNCAWRVNGRLLDLVLQIFRDKGCMRLGVPPPRSEAPRPAKHQLPPGSTPVHKSELRKELARCLKAAREMHSLRSEALYRLSLAQHLRDRVFWLPHNMDFRGRTYPCPPHFNHLGSDLARALLEFAEGRPLGPRGLDWLKIHLINLTGLRKRDSLRMRLAFADEVMGEILDSADNPLTGQKWWMKADEPWQTLACCMEVAQAVRSPDPTAYVSHLPVHQDGSCNGLQHYAALGRDSVGAASVNLTPSDLPQDVYREVATQVEELRQQDAKEGLQVAQALEGFVSRKVVKQTVMTVVYGVTRYGGRLQIEKRLRELSDFPQEFVWEASHYLVRQVFKSLQEMFSSTRAIQRWLTESANLISHAGWPVEWVTPLGIPIIQPYHRESKIQVKGGLQSITFTSSVDDSQKPNTLKQKNGFPPNFIHSLDSSHMMLTALHCYRKGLTFVSVHDCFWTHAADIPMMNEVCREQFVRLHSEPILEDLAKFLEKRFCSVSKSLKPSELALITKLQETLRSLPETGKSFKGSMRIGP", "length": 1199 }, "evidence": [ { "id": "RGD:1304599", "url": "https://alliancegenome.org/gene/RGD:1304599#orthology", "database": "AGR" }, { "id": "MGI:1915843", "url": "https://alliancegenome.org/gene/MGI:1915843#orthology", "database": "AGR" }, { "id": "HGNC:9200", "url": "https://alliancegenome.org/gene/HGNC:9200#orthology", "database": "AGR" }, { "id": "FB:FBgn0261938", "url": "https://alliancegenome.org/gene/FB:FBgn0261938#orthology", "database": "AGR" }, { "id": "SGD:S000001858", "url": "https://alliancegenome.org/gene/SGD:S000001858#orthology", "database": "AGR" }, { "id": "Q9VPW4", "url": "https://omabrowser.org/oma/group/Q9VPW4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A9J7H0H6-1", "protein_name": "DNA-directed RNA polymerase", "gene_name": "Polrmt", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSALRWTRGAAGLGRALSSSGRRRPTSEEGTLSSLCSSRRSSAASPREQDVQKEWGHAELLEVLEARVRQLRAESMSEATVKKVQMDQPPNGHSSRWAQKLEAERQVKGKRQKELLDQHQKHTLTLQMEPWIWSKKLAGCLQQSKKGAPKSLEEEEQLLTQALKAALQKLSSCTLAKSNATAVEANILLLQQKFLAFFECCACTDNVPLAHHVLVTQHSKCDKQQLLTLDMYNTVMLSWARKGSFKELVYVFIMLKDAGLSPNLWSYAAALQCMGRRDQDVHIIQRCLKQMMEEGFQPQQLFTDLVLTGEERDALLRAVVKAEPAFILPPQAPEPVNTSILLQEVYAKQKGPKSYPKLHLPLETLQDLFHQQLHVELSANVCVQSVEKAPVMTKEVIEARKTLKTLQGQWEAELLRVLQQTKATMAHQAQEGQPTLYPFLCLLSEGEFVSMLMQVLRLLPAQGEPLLHLAHDLGLRVLNRHLVKQKQATNHVQKLGQHYSQYLRLLASDTQVEAPCLPREYWESLGPLETPMQQPWSLTVLLHLGKQLAEMLVQAVQMPRNLSTPQASRHLIPVLYHVYSFRSYRQIGILKPHPAFSKLLETAAEPTLILETTEVPMLCPPLPWTTPHTGAYLLSSTKLMRATEGTTQHQHLLERCAPAQLHGALDALTQLGNCAWRVNGRLLDLVLQIFRDKGCTRLGVPPPRSEAPQPAQLRLPPGATPLHKAELRKELSRCLKIAREMHSLRIEALYRLSLAQHLRNRVFWLPHNMDFRGRTYPCPPYFNHLGSDLARALLEFAEGRPLGPRGLDWIKIHLVNLTGLRKRDSLRMRLRFADEVMEEILDSADNPMTGRKWWMEADEPWQTLACCIEVARAVRSPDAAAYVSHLPVHQDGSCNGLQHYAALGRDSAGAASVNLMPSDLPQDVYREVAAQVEELRQRDAKDGLQVAHVLKGFITRKVVKQTVMTVVYGVTRYGGRLQIEKRLRELSNFPQEFVWEASHYLVRLVFKSLQEMFSSTRAIQHWLTESANLISHSGWPVEWVTPLGIPVIQPYHREAKVQVKGGIQSITMTSSMDITQKPNTLKQKNGFPPNFIHSLDSAHMMLTALHCYRKGLTFVSVHDCFWTHAADIPVMNEVCREQFVRLHSQPILEDLAKFLEKRFCSVSSSQKPSELALATKLQKTLQSLPKTGTFDLSQVMKSTYFFS", "length": 1203 }, "evidence": [ { "id": "Q9VPW4", "url": "https://omabrowser.org/oma/group/Q9VPW4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0ACD6B7G4-1", "protein_name": "DNA-directed RNA polymerase", "gene_name": "polrmt", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSLLRLCAYSAALTRSFAADGCLRSFLKGDCCRMCLRIRINGERQIQDKTWATIYRRHYSVIPKKDDGKKRVWEQSQLLDVLEARIQQLHSDAIVDVKHSKVQIIKAKQRAKKTSPGKSQKNLPGEKAEMLKSGPSAQKKNVTEGVTPANTHASRWMAKLNREMWINPKTKTSKKVIKTGQSSKTKHCTNNAQNKGKGFRVSERLLAKFPDLQKIHSGEVSLISVISDKALVNEGELDVSVPAPEKLLVDKEGNRYEDSHLRVRCYLEACMFLDDVSRAHNYLLSHHRQLSKRSQLSISTYNIVMRMWAKKGSINNIRRLFSLIEEAGMKPNVTSYCAALECMGRMQNCETVVIARCLQQMGADGLSVDDVLSQCVFKKDEREMVLRAVQLVIPHFQPSVSKTQPVCSLPLVKQFYAEREDAIYPKLDYSLKELQDRFNLQLAMEKATTVTINSVEALKPVTENMAHMRELLAKQRKHWEKALLQALKDRKQMMSNNSQKSWNTCLYPYLCILDDQEYVDIMLQSLDKLSPNGESLLFMADEMGNRVYNLYCIRQKSQSQMVEKLRSIYSSYAELLANDTETNGMLPRECWTNLEISGNRSGPSLLSDDTPWPMILMVQLGSFLVDLMVHELKIQSNILNPALEKKLIPILYHMYTFRSNHKIGFIKPHPILTRILREATETKLTFDSYVMPMLCPPVPWTSPKSGAYLLTPAKLMRASDGAMQHQLLLEKTQEEDLHAVLDSLNQVGSCPWKINKPLLDIIISIFNDKGSDKLSIPPPLSEAPEIPRFNPHDPSYTQVEKAFMKREGIKAKKVVAEMHSLRMDALYKLSIANHVRDKIFWFPHNMDFRGRTYPLPPYFNHLGSDVTRALLLFAEGRPLGPKGLDWLKIHLVNLTGLKKQSSLDGRLEYAESIMEDILDSADHPLDGRKWWMNADEPWQALACCMEIANASRSPDHHKFISYFPVHQDGSCNGLQHYAALGRDVIGATSVNLMPCALPQDVYSGVAKQVEEFRVRDAERGLKIAQVLQGFISRKVVKQTVMTVVYGVTRYGGRLQIEKRLKEIDDFPKDYVWDASHYLVVQVFNSLKEMFTGTREIQEWLTESARLIAKSGRTVEWVTPLGLPIIQPYHRIRNQILKGNIQNLNIHISHDANEKPDSMKQKNAFPPNFIHSLDSTHMMLTSLHCHRAGLTFVSVHDCYWTHAVTVDIMNRVCREQFVALHSQPILEELSWFLLQKYSRRPPVGSKPKKLLEYYTLMKVLSSVPQTGDFDLEKVKDSVYFFS", "length": 1281 }, "evidence": [ { "id": "MGI:1915843", "url": "https://alliancegenome.org/gene/MGI:1915843#orthology", "database": "AGR" }, { "id": "HGNC:9200", "url": "https://alliancegenome.org/gene/HGNC:9200#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E1BCZ0-1", "protein_name": "DNA-directed RNA polymerase", "gene_name": "POLRMT", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSALRCGRRAAGLRRALWPKGHPCFLAEEGTLGGVWGRKRSLSASACEQDRRKGCGHAELLEVLEARVRQLQAEGTAEEVMVKRVAMAQAPEAGGIWPPRQAPVGAEGAAPVLSSHWVQKLDKDQQLIEKRLQQLEGKLPKIVEKSTWEKRLRMEPRLLSRKLAGQLQQWERKRPQSPWEEQLARLLQEAPKKLSREADEGSESRLEGQRQKLLAFLECCLLTGHLPLAHHVLVAQHSRAPQQQLLTLPMYNTVMLGWARQGSFKELMYVFFMLKDAGLAPDLLSYAAALQCMGRLDQDAGTIRRCLKQMEQDGLSLQGLFSAVPLSTEEREELLRAVRKARPAFSPQPPPPPPPQVNTSPLLQEIYAKDPSVSYPKLHLSLKELQGLFRQQLGVEMATTVTVESVEKAPLLTEEVLQARKTLAALRAEWESVLSLELQETKESEARAAAEGRPSLFPYLCLLSEKELVGLLLQTLQALPSHGESLFFLAHELGVRVLKRKRLRNQVEELEQRYFEYLHLLASDTQVAEPCLPRQRWEALGVPEAPPEQPWPVSVLVQLGKQLAEVLVRAVQMPSSLAAPRGPSTLIPVLYHVYSFRSFRQIGILKPHPAFTQLQETAAERTLIFESTEVPMLCPPLPWTSPHSGAFLLSPTKMMRSLEGTQQHQLLLERCPPAELHGALDALTQLGNCAWRVNGRVLDLVLDLFRDKGCPRLGVPAPPTEAPRPPEGRQTPKGCLLPEASPADKAEMRRELARRLKVAREMQSLRADALYRLSLAQHLRNHVFWLPHNMDFRGRTYPCSPHFNHLGSDLARALLEFAQGRPLGPHGLDWLKIHLINLTGLKKRESLQTRRDYADAVMEDILDSAERPMTGRKWWMEADEPWQTLACCMEIAQVVHSPDPTTYISHFPVHQDGSCNGLQHYAALGRDSTGATSVNLSPSDLPQDVYSEVAAQVEVFRRQDAKQGVRVAQVLEGFISRKVVKQTVMTVVYGVTRYGGRLQIEKRLRELEDFPQEFVWEASHYLVRQVFNSLQEMFSGTRSIQRWLTESARLISLTGSAVEWITPLGVPIIQPYHRDSKVMVRAIKGGLQSLTFSSSVDTNQKPNTLKQKNGFPPNFIHSLDSTHMMLTALYCYRKGLTFVSVHDCFWTHAADVGVMNQVCREQFVRLHSQPILHDLSRFLIKRFCSDSRTSKSMWVSRLKDTLLSVPPTGTFDLDQVKRSTFFFS", "length": 1224 }, "evidence": [ { "id": "Q9VPW4", "url": "https://omabrowser.org/oma/group/Q9VPW4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1BZ13-1", "protein_name": "DNA-directed RNA polymerase", "gene_name": "POLRMT", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALLRLRAALLGPARLRGGGIPWSVLRCYSSASAKEKARRNAICERTELLEVLKARVKQLQTSNIPEVTINKVELAPVQSDRHHNPLQKVVDARTAVEHLVPKQSSSWTEKLKKEMYIRQLKVEKKLSIAASQMTPEGQPKVKTKVKVKTKVKAKAKTKTKSKAKSKKSQKSPKATASTSRNQSHAGPSSANTYHKPRVEEMKQDVKAQKPQRVHEDRSSQRKIMQQTNQSNLECLLYLQQPEEAEKLLLLYHSNPMKRKLLNVDAYNVVMRGWARKGCLHRVIHLFSMLESISLRPNLDSYAVLLECMTQSQASTKAIWRCVQHLKKDGFHVDELFQKCLFEGDEKEMVLKAIRIIQPDYQLPPPPKPEICKTALLKNFYSEEKMVSYPKLDFTVQELRERFQQQLEMELNSTITIESVESTKPLTPQAIKARQQLATFRSQWRGAILQALQKSKHNMSQVKTMSGHSVLYPYLCLLPDEEYVDIMMQILNSLSPQGESLAVLARELGSKVYNRYLTQRKLHSGQLEKVQEIYKNYIHLLAKDSQPSEYLPREYWEKLVAEAGYGPSLNLKDCSWPYVLLMRLGMYLLEILVHAVKVPRNTLNPRLPSKLIPVLYHIYSFRSSWQVGLIKPHPIFSQIVSDAAETMLTFNSSAIPMLCPPVPWTSPHFGAFVLSDTKLMRYVDGAIQHQQLLDQCPQVNLHPVLDALNQLGNCAWKINQPVLDIIISIFNDKGNEKLDIPPPVSEAPKPPVSPSSSSALHKSQKHELLLCKKKAAEMHSLRMDALYKLSIANYVRDKVFWFPHNMDFRGRTYPCPPYFNHLGNDVTRAILLFAEGRPLGPKGLDWLKIHLINLTGLKKKNALQERLDYANEIMEEILDSADHPLTGRKWWMNTDEPWQVLACCMEIAKASRSPDPAAFISHFPVHQDGSCNGLQHYAALGRDLIGAISVNLMPCNVPQDVYSAVAQQVEEFRKKDAEEGLRIAQVLEGFIGRKVVKQTVMTVVYGVTRYGGRLQMEKRLKEIEFPEEYLWEASHYLVKQVFNGIKEMFSATRDIQNWLTESAKLIAQSGRTVEWVTPLGLPIVQPYYRIRPTVLTCSMQNLSVKNSSNNNQKPDTVKQKNAFPPNFIHSLDSTHMMLTALHCFRQGLTFVSVHDCYWTHALTVDIMNEICRQQFVALHSQKILEDLSKFMLENYCSPDRESRALWQKKLMEQLSNVPKTGEFNLNKVIDSTYFFS", "length": 1236 }, "evidence": [ { "id": "Q9VPW4", "url": "https://omabrowser.org/oma/group/Q9VPW4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O00411-1", "protein_name": "DNA-directed RNA polymerase, mitochondrial", "gene_name": "POLRMT", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSALCWGRGAAGLKRALRPCGRPGLPGKEGTAGGVCGPRRSSSASPQEQDQDRRKDWGHVELLEVLQARVRQLQAESVSEVVVNRVDVARLPECGSGDGSLQPPRKVQMGAKDATPVPCGRWAKILEKDKRTQQMRMQRLKAKLQMPFQSGEFKALTRRLQVEPRLLSKQMAGCLEDCTRQAPESPWEEQLARLLQEAPGKLSLDVEQAPSGQHSQAQLSGQQQRLLAFFKCCLLTDQLPLAHHLLVVHHGQRQKRKLLTLDMYNAVMLGWARQGAFKELVYVLFMVKDAGLTPDLLSYAAALQCMGRQDQDAGTIERCLEQMSQEGLKLQALFTAVLLSEEDRATVLKAVHKVKPTFSLPPQLPPPVNTSKLLRDVYAKDGRVSYPKLHLPLKTLQCLFEKQLHMELASRVCVVSVEKPTLPSKEVKHARKTLKTLRDQWEKALCRALRETKNRLEREVYEGRFSLYPFLCLLDEREVVRMLLQVLQALPAQGESFTTLARELSARTFSRHVVQRQRVSGQVQALQNHYRKYLCLLASDAEVPEPCLPRQYWEELGAPEALREQPWPLPVQMELGKLLAEMLVQATQMPCSLDKPHRSSRLVPVLYHVYSFRNVQQIGILKPHPAYVQLLEKAAEPTLTFEAVDVPMLCPPLPWTSPHSGAFLLSPTKLMRTVEGATQHQELLETCPPTALHGALDALTQLGNCAWRVNGRVLDLVLQLFQAKGCPQLGVPAPPSEAPQPPEAHLPHSAAPARKAELRRELAHCQKVAREMHSLRAEALYRLSLAQHLRDRVFWLPHNMDFRGRTYPCPPHFNHLGSDVARALLEFAQGRPLGPHGLDWLKIHLVNLTGLKKREPLRKRLAFAEEVMDDILDSADQPLTGRKWWMGAEEPWQTLACCMEVANAVRASDPAAYVSHLPVHQDGSCNGLQHYAALGRDSVGAASVNLEPSDVPQDVYSGVAAQVEVFRRQDAQRGMRVAQVLEGFITRKVVKQTVMTVVYGVTRYGGRLQIEKRLRELSDFPQEFVWEASHYLVRQVFKSLQEMFSGTRAIQHWLTESARLISHMGSVVEWVTPLGVPVIQPYRLDSKVKQIGGGIQSITYTHNGDISRKPNTRKQKNGFPPNFIHSLDSSHMMLTALHCYRKGLTFVSVHDCYWTHAADVSVMNQVCREQFVRLHSEPILQDLSRFLVKRFCSEPQKILEASQLKETLQAVPKPGAFDLEQVKRSTYFFS", "length": 1230 }, "evidence": [ { "id": "RGD:1304599", "url": "https://alliancegenome.org/gene/RGD:1304599#orthology", "database": "AGR" }, { "id": "MGI:1915843", "url": "https://alliancegenome.org/gene/MGI:1915843#orthology", "database": "AGR" }, { "id": "HGNC:9200", "url": "https://alliancegenome.org/gene/HGNC:9200#orthology", "database": "AGR" }, { "id": "FB:FBgn0261938", "url": "https://alliancegenome.org/gene/FB:FBgn0261938#orthology", "database": "AGR" }, { "id": "SGD:S000001858", "url": "https://alliancegenome.org/gene/SGD:S000001858#orthology", "database": "AGR" }, { "id": "Q9VPW4", "url": "https://omabrowser.org/oma/group/Q9VPW4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P13433-1", "protein_name": "DNA-directed RNA polymerase, mitochondrial", "gene_name": "RPO41", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLRPAYKSLVKTSLLQRRLISSKGSKLFKPSPDSTSTILISEDPLVTGSSPTSSTTSGIISSNDFPLFNKNRKDAKSSISYQWKNPSELEFDPFNKSHASAVTSMTRTRDVMQLWSLLEACLQSNLMKRAFSILESLYLVPEHKQRFIEDYNMYLNSFSKNDPNFPILKMNEKLTNDLETSFKDVNYNDKTLAIMIHHALNFHSTTSSMLLKPIISAYLKMSVNGIREIFSCLDILTISDLNILMNDLKVITPSQLPNSVRPILESLTLSPTPVNNIENEEGLNKVEAENDSKLHKASNASSDSIKKPSLDPLREVSFHGSTEVLSKDAEKLIAVDTIGMRVIRHTLLGLSLTPEQKEQISKFKFDANDNVLKMKPTKNDDNNNSINFFEIYNSLPTLEEKKAFESALNIFNQDRQKVLENRATEAARERWKHDFEEAKARGDISIEKNLNVKLWKWYNEMLPLVKEEINHCRSLLSEKLSDKKGLNKVDTNRLGYGPYLTLIDPGKMCVITILELLKLNSTGGVIEGMRTARAVISVGKAIEMEFRSEQVLKSESQAFRDVNKKSPEFKKLVQNAKSVFRSSQIEQSKILWPQSIRARIGSVLISMLIQVAKVSVQGVDPVTKAKVHGEAPAFAHGYQYHNGSKLGVLKIHKTLIRQLNGERLIASVQPQLLPMLVEPKPWVNWRSGGYHYTQSTLLRTKDSPEQVAYLKAASDNGDIDRVYDGLNVLGRTPWTVNRKVFDVVSQVWNKGEGFLDIPGAQDEMVLPPAPPKNSDPSILRAWKLQVKTIANKFSSDRSNRCDTNYKLEIARAFLGEKLYFPHNLDFRGRAYPLSPHFNHLGNDMSRGLLIFWHGKKLGPSGLKWLKIHLSNLFGFDKLPLKDRVAFTESHLQDIKDSAENPLTGDRWWTTADKPWQALATCFELNEVMKMDNPEEFISHQPVHQDGTCNGLQHYAALGGDVEGATQVNLVPSDKPQDVYAHVARLVQKRLEIAAEKGDENAKILKDKITRKVVKQTVMTNVYGVTYVGATFQIAKQLSPIFDDRKESLDFSKYLTKHVFSAIRELFHSAHLIQDWLGESAKRISKSIRLDVDEKSFKNGNKPDFMSSVIWTTPLGLPIVQPYREESKKQVETNLQTVFISDPFAVNPVNARRQKAGLPPNFIHSLDASHMLLSAAECGKQGLDFASVHDSYWTHASDIDTMNVVLREQFIKLHEVDLVLRLKEEFDQRYKNYVKIGKLKRSTDLAQKIIRIRKDLSRKLGRSTTLADEIYFEKKRQELLNSPLIEDRNVGEKMVTTVSLFEDITDLDALELENGGDENSGMSVLLPLRLPEIPPKGDFDVTVLRNSQYFFS", "length": 1351 }, "evidence": [ { "id": "RGD:1304599", "url": "https://alliancegenome.org/gene/RGD:1304599#orthology", "database": "AGR" }, { "id": "MGI:1915843", "url": "https://alliancegenome.org/gene/MGI:1915843#orthology", "database": "AGR" }, { "id": "HGNC:9200", "url": "https://alliancegenome.org/gene/HGNC:9200#orthology", "database": "AGR" }, { "id": "FB:FBgn0261938", "url": "https://alliancegenome.org/gene/FB:FBgn0261938#orthology", "database": "AGR" }, { "id": "SGD:S000001858", "url": "https://alliancegenome.org/gene/SGD:S000001858#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q8BKF1-1", "protein_name": "DNA-directed RNA polymerase, mitochondrial", "gene_name": "Polrmt", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSALRWTRSAAGLGRVLRSPGPHRPPSEEGTFGGFCSSRRSSAASPREQHVLREWGHAELLEVLEARVRQLRAEGTPEMRVKKVQVDRPPQGHSSRWAQKLEAEKRVKQRRQKEVDQQKQALTQEFWTLHKEPKIWNKKLAGYLQPSKKGTPTNSEEKQLAQALQAALGRLSSREAEALARKKAKAVEAQILVLQQKFLAFFECCVCTGQVPLAHHVLVTHHNNGDRQQVLTLHMYNTVMLGWARKGSFRELVYVFLMLKDAGLSPDLCSYAAALQCMGRRDQDVRTIQRCLKQMMEEGFQPQLLFTDLVLEEEDRAALLRAVVKAEPAFRPPPQAPSPVNTSTLLKDIYSKEGPVSYPKLHLPLDTLQDLFYQQLHVELSSSVCVQSVEKAPVMSKEVIEARKTLQALREQWEVELLRVLRETKATMGRQAYEGQPTLYPFLCLLSEGEFVSILMQVLKVLPAQGEPLIQLAHNLGLRVLNRHLVKQKQVTNHVQKLGQRYSQYLQLLASDTQVAPCLPREYWESLGPLEAPAQQPWSVPVLLQLGKQLAELLVQAVQMPRSLAARQGAQRSIPVLYHVYSFRSYRQVGILKPHPAFTHLLETAAEPTLTFETTEVPMLCPPLPWTSLHSGAYLLSSTKLMRATEGTTQHQRLLEQCPPAQLHGPLDALTQLGNCAWRVNGHLLDLVLQIFRDKGCMPLGVPPPRSEAPRPARYQLPPGSTPVHKSELRKELARCLKVAREMHSLRSEALYRLSLAQHLRHRVFWLPHNMDFRGRTYPCPPHFNHLGSDLARALLEFAEGRPLGPRGLDWLKIHLINLTGLKKGDSLRMRLAFADEVMEEILDSADNPLTGRKWWMEADEPWQTLACCMEVAHAVRSPDPAAYISHLPVHQDGSCNGLQHYAALGRDSVGAASVNLTPSDLPQDVYREVATQVEEFRQQDAKEGLRVAQVLEGFISRKVVKQTVMTVVYGVTRYGGRLQIEKRLRELSDFPQEFVWEASHYLVRQVFKSLQEMFTSTRAIQHWLTESANLISHAGWPVEWVTPLGIPIIQPYHRESKVQVKGGLQSITLTSSVDESQKPNTLKQKNGFPPNFIHSLDSSHMMLTALHCYRKGLIFVSVHDCFWTHAADIPTMNEVCREQFVRLHSQPILEDLAKFLKKRFCSVSSIKSLKSSERALVTKLQETLQSLPKTGTFDLGQVIRSTYFFS", "length": 1207 }, "evidence": [ { "id": "RGD:1304599", "url": "https://alliancegenome.org/gene/RGD:1304599#orthology", "database": "AGR" }, { "id": "MGI:1915843", "url": "https://alliancegenome.org/gene/MGI:1915843#orthology", "database": "AGR" }, { "id": "HGNC:9200", "url": "https://alliancegenome.org/gene/HGNC:9200#orthology", "database": "AGR" }, { "id": "FB:FBgn0261938", "url": "https://alliancegenome.org/gene/FB:FBgn0261938#orthology", "database": "AGR" }, { "id": "SGD:S000001858", "url": "https://alliancegenome.org/gene/SGD:S000001858#orthology", "database": "AGR" }, { "id": "Q9VPW4", "url": "https://omabrowser.org/oma/group/Q9VPW4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrial DNA-directed RNA polymerase complex", "id": "GO:0034245", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034245", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW4", "url": "https://www.uniprot.org/uniprotkb/Q9VPW4" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW4", "url": "https://www.uniprot.org/uniprotkb/Q9VPW4" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW4", "url": "https://www.uniprot.org/uniprotkb/Q9VPW4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "mitochondrial promoter sequence-specific DNA binding", "id": "GO:0001018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001018", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW4", "url": "https://www.uniprot.org/uniprotkb/Q9VPW4" } ], "pmid": "" }, { "name": "3'-5'-RNA exonuclease activity", "id": "GO:0000175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000175", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW4", "url": "https://www.uniprot.org/uniprotkb/Q9VPW4" } ], "pmid": "" }, { "name": "DNA-directed RNA polymerase activity", "id": "GO:0003899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003899", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW4", "url": "https://www.uniprot.org/uniprotkb/Q9VPW4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA replication, synthesis of primer", "id": "GO:0006269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006269", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW4", "url": "https://www.uniprot.org/uniprotkb/Q9VPW4" } ], "pmid": "" }, { "name": "mitochondrial transcription", "id": "GO:0006390", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006390", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW4", "url": "https://www.uniprot.org/uniprotkb/Q9VPW4" } ], "pmid": "" }, { "name": "DNA synthesis involved in mitochondrial DNA replication", "id": "GO:0110166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110166", "evidence": [ { "database": "UniProtKB", "id": "Q9VPW4", "url": "https://www.uniprot.org/uniprotkb/Q9VPW4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 278, "end_pos": 280, "annotation": "n_glycosylation_sequon" }, { "start_pos": 636, "end_pos": 638, "annotation": "n_glycosylation_sequon" }, { "start_pos": 793, "end_pos": 795, "annotation": "n_glycosylation_sequon" }, { "start_pos": 879, "end_pos": 881, "annotation": "n_glycosylation_sequon" }, { "start_pos": 978, "end_pos": 980, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "21248", "name": "", "equation": "RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P25167-1", "P04052-1", "P08266-1", "P20028-1", "P91875-1", "Q9VPW4-1", "A8JUY3-1" ], "evidence": [ { "id": "21248", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/21248" } ] }, { "id": "R-DME-163296", "name": "Association of TFAM:mt promoter complex with POLRMT:TFB2M", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VH38-1", "Q9VPW4-1" ], "evidence": [ { "id": "R-DME-163296", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-163296" } ] }, { "id": "R-DME-9914404", "name": "POLRMT and POLG bind the mitochondrial L strand replication origin (OriL)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q27607-1", "Q9VL76-1", "Q9VPW4-1" ], "evidence": [ { "id": "R-DME-9914404", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9914404" } ] }, { "id": "R-DME-9914409", "name": "POLRMT polymerizes RNA primer for mitochondrial L strand replication", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [ "R-ALL-110731" ], "output_participant_list": [ "R-DME-163267" ], "enzyme_list": [ "Q27607-1", "Q9VL76-1", "Q9VPW4-1" ], "evidence": [ { "id": "R-DME-9914409", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9914409" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-110731", "participant_name": "UTP [mitochondrial matrix]", "crossref": [ { "id": "46398", "database": "ChEBI", "url": "" }, { "id": "ZINC000003861755", "database": "ZINC", "url": "" }, { "id": "C00075", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-DME-163267", "participant_name": "PolrMT [mitochondrial matrix]", "crossref": [ { "id": "NP_001259853.1", "database": "RefSeq", "url": "" }, { "id": "FBgn0261938", "database": "FlyBase", "url": "" }, { "id": "Q9VPW4", "database": "UniProt", "url": "" }, { "id": "NP_608565.1", "database": "RefSeq", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A8JUY3", "gene_name": "Polr3A", "activity": [ { "ec_number": "2.7.7.6", "activity": "RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate.", "evidence": [ { "id": "A8JUY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8JUY3" } ] }, { "ec_number": "2.7.7.6", "activity": "", "evidence": [ { "id": "A8JUY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8JUY3" } ] } ] }, { "uniprot_ac": "P04052", "gene_name": "Polr2A", "activity": [ { "ec_number": "2.7.7.6", "activity": "RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate.", "evidence": [ { "id": "P04052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04052" } ] }, { "ec_number": "2.7.7.6", "activity": "", "evidence": [ { "id": "P04052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04052" } ] } ] }, { "uniprot_ac": "P08266", "gene_name": "Polr2B", "activity": [ { "ec_number": "2.7.7.6", "activity": "RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate.", "evidence": [ { "id": "P08266", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08266" } ] }, { "ec_number": "2.7.7.6", "activity": "", "evidence": [ { "id": "P08266", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08266" } ] } ] }, { "uniprot_ac": "P20028", "gene_name": "Polr1B", "activity": [ { "ec_number": "2.7.7.6", "activity": "RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate.", "evidence": [ { "id": "P20028", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20028" } ] }, { "ec_number": "2.7.7.6", "activity": "", "evidence": [ { "id": "P20028", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20028" } ] } ] }, { "uniprot_ac": "P25167", "gene_name": "Polr3B", "activity": [ { "ec_number": "2.7.7.6", "activity": "RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate.", "evidence": [ { "id": "P25167", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P25167" } ] }, { "ec_number": "2.7.7.6", "activity": "", "evidence": [ { "id": "P25167", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P25167" } ] } ] }, { "uniprot_ac": "P91875", "gene_name": "PolR1A", "activity": [ { "ec_number": "2.7.7.6", "activity": "RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate.", "evidence": [ { "id": "P91875", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P91875" } ] }, { "ec_number": "2.7.7.6", "activity": "", "evidence": [ { "id": "P91875", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P91875" } ] } ] }, { "uniprot_ac": "Q27607", "gene_name": "PolG1", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "Q27607", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q27607" } ] }, { "ec_number": "3.1.11.-", "activity": "", "evidence": [ { "id": "Q27607", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q27607" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "Q27607", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q27607" } ] } ] }, { "uniprot_ac": "Q9VH38", "gene_name": "mtTFB2", "activity": [ { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "Q9VH38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VH38" } ] } ] }, { "uniprot_ac": "Q9VL76", "gene_name": "mtDNA-helicase", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "Q9VL76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VL76" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": 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"database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "R-DME-446199", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-446199", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001259857", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259857", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "53008", "url": "https://www.rhea-db.org/rhea/53008", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q9VPX8", "url": "https://www.uniprot.org/uniprotkb/Q9VPX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VPX8-1", "url": "https://www.uniprot.org/uniprotkb/Q9VPX8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIEVLCLLLGRILLLLVGGYELMWRLRERLNALAVRSYDLWRSKAAREAHERRVLADCRSQLTKTPQHLVLVISPVDAGVDAVLLSRIFDFALDVGIKHVSLYDRRTKGRGYVDMADLCRSTNADTGSCLKWPPVASPSKLENQPKNGQKTNGYVNGSHSPQLQLHQISASDGHALIADVCRELYEDSKTELVQSLLKQKREALTEQISDMLSKRLGFEAPEPELGIVFARQTCTYGLLPWHARFTEFHTHPSGRHFDVETFASILCKYSRCEQRWGT", "length": 278, "header": "tr|Q9VPX8-1|Q9VPX8_DROME Isoform 1 of ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyldiphosphate specific] OS=Drosophila melanogaster OX=7227 GN=Tango14 PE=3 SV=1 CANONICAL=Q9VPX8-1" }, "isoforms": [ { "isoform_ac": "Q9VPX8-1", "url": "https://www.uniprot.org/uniprotkb/Q9VPX8/entry#Q9VPX8-1", "sequence": { "sequence": "MIEVLCLLLGRILLLLVGGYELMWRLRERLNALAVRSYDLWRSKAAREAHERRVLADCRSQLTKTPQHLVLVISPVDAGVDAVLLSRIFDFALDVGIKHVSLYDRRTKGRGYVDMADLCRSTNADTGSCLKWPPVASPSKLENQPKNGQKTNGYVNGSHSPQLQLHQISASDGHALIADVCRELYEDSKTELVQSLLKQKREALTEQISDMLSKRLGFEAPEPELGIVFARQTCTYGLLPWHARFTEFHTHPSGRHFDVETFASILCKYSRCEQRWGT", "length": 278, "header": "tr|Q9VPX8-1|Q9VPX8_DROME Isoform 1 of ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyldiphosphate specific] OS=Drosophila melanogaster OX=7227 GN=Tango14 PE=3 SV=1 CANONICAL=Q9VPX8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VPX8", "url": "https://www.uniprot.org/uniprotkb/Q9VPX8" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VPX8", "url": "https://www.uniprot.org/uniprotkb/Q9VPX8" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPX8", "url": "https://www.uniprot.org/uniprotkb/Q9VPX8" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPX8", "url": "https://www.uniprot.org/uniprotkb/Q9VPX8" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VPX8", "url": "https://www.uniprot.org/uniprotkb/Q9VPX8" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VPX8", "url": "https://www.uniprot.org/uniprotkb/Q9VPX8" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VPX8", "url": "https://www.uniprot.org/uniprotkb/Q9VPX8" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPX8", "url": "https://www.uniprot.org/uniprotkb/Q9VPX8" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPX8", "url": "https://www.uniprot.org/uniprotkb/Q9VPX8" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VPX8", "url": "https://www.uniprot.org/uniprotkb/Q9VPX8" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VPX8", "url": "https://www.uniprot.org/uniprotkb/Q9VPX8" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG4775", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG4775", "resource": "KEGG Pathway" }, { "id": "R-DME-446199", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-446199", "resource": "Reactome", "description": "Synthesis of dolichyl-phosphate" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZFM4-1", "protein_name": "Dehydrodolichyl diphosphate synthase complex subunit NUS1", "gene_name": "Nus1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTGLYELVWRVLHLLFCLYRTLTSWLRVRFGTWNWIWRRCCRAASAAVLAPLGFTLRKLPAVGRNRRHHRHPHRGPGPAATHPRLRWRADGRSLQKLPVHMGLVITEEVQEPSFSDIASLVVWCMAVGISYISVYDHQGIFKRNNSRLMDEILKQQQELLGQDCSKYSAEFANSNDKDDQVLNCPSAVKVLSPEDGKADIVRAAQDFCQSVAQQQRRPTELGVELLDSLLSSHGFPDPDLVLKFGPVDSTLGFLPWQIRLTEIISLPSHSNISYEDLFSALRQYAACEQRLGK", "length": 293 }, "evidence": [ { "id": "RGD:1307879", "url": "https://alliancegenome.org/gene/RGD:1307879#orthology", "database": "AGR" }, { "id": "MGI:1196365", "url": "https://alliancegenome.org/gene/MGI:1196365#orthology", "database": "AGR" }, { "id": "HGNC:21042", "url": "https://alliancegenome.org/gene/HGNC:21042#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040718-48", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040718-48#orthology", "database": "AGR" }, { "id": "FB:FBgn0031312", "url": "https://alliancegenome.org/gene/FB:FBgn0031312#orthology", "database": "AGR" }, { "id": "SGD:S000002352", "url": "https://alliancegenome.org/gene/SGD:S000002352#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q12063-1", "protein_name": "Dehydrodolichyl diphosphate synthase complex subunit NUS1", "gene_name": "NUS1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MPTMIKKDDKAMEPPNEKPHRKIERDDVPESSNHIPPPESGVLKGGKVNSKTRALKAVTSIIADADENPQKKVNNETNGVQKQKTEDLSKRIGKFEYLFYKFLLVLLYICFGLFRYGQYQYNKMKLRIFSIIYNHAYTPQLIRQDVIPLKKIPKRLAAILEVKPVGDVGGGVTGLLNDASEIVCWTVSAGIKHLMLYDYDGILQRNVPELRMEIHSNLAKYFGPAHVPNYAVKIPHSNKIFYNLDGIETETDVGNEIEANQEKDKIAIEISLLSNRDGRETIVDLTKTMAELCAVNELSVSDITMDLVDSELKQLVGPEPDLLLYFGPSLDLQGFPPWHIRLTEFYWEKDNNEVIYSVFIRGLRQYAGCKVNVGK", "length": 375 }, "evidence": [ { "id": "RGD:1307879", "url": "https://alliancegenome.org/gene/RGD:1307879#orthology", "database": "AGR" }, { "id": "MGI:1196365", "url": "https://alliancegenome.org/gene/MGI:1196365#orthology", "database": "AGR" }, { "id": "HGNC:21042", "url": "https://alliancegenome.org/gene/HGNC:21042#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040718-48", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040718-48#orthology", "database": "AGR" }, { "id": "FB:FBgn0031312", "url": "https://alliancegenome.org/gene/FB:FBgn0031312#orthology", "database": "AGR" }, { "id": "SGD:S000002352", "url": "https://alliancegenome.org/gene/SGD:S000002352#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q6DHR8-1", "protein_name": "Dehydrodolichyl diphosphate synthase complex subunit nus1", "gene_name": "nus1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASLYEMVWRFLHALLYLQRAIVAWFRVHIWRWKLAVVDLLLPLALGFHNQKKTGPKGTRTSRRVRWGADGRTLEKLPLHVGLLVTEEEIHYTDIANLVVWCMAVGISYVSVYDNQGVFKRNNSRLMEEILKQQQELLGMGSSKYSVEILKNGTNKQEHQVLSCQSMVKVLSPDDGRLSIVQAAQQLCRAVEQKEKTSKDINVSVLDSLLKESKNIPDPDLVLKFGTVQSTLGFLPWHIRLTEIISMPSHIDASYDDLYDALQRFAGCEQRLGK", "length": 274 }, "evidence": [ { "id": "RGD:1307879", "url": "https://alliancegenome.org/gene/RGD:1307879#orthology", "database": "AGR" }, { "id": "MGI:1196365", "url": "https://alliancegenome.org/gene/MGI:1196365#orthology", "database": "AGR" }, { "id": "HGNC:21042", "url": "https://alliancegenome.org/gene/HGNC:21042#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040718-48", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040718-48#orthology", "database": "AGR" }, { "id": "FB:FBgn0031312", "url": "https://alliancegenome.org/gene/FB:FBgn0031312#orthology", "database": "AGR" }, { "id": "SGD:S000002352", "url": "https://alliancegenome.org/gene/SGD:S000002352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q96E22-1", "protein_name": "Dehydrodolichyl diphosphate synthase complex subunit NUS1", "gene_name": "NUS1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTGLYELVWRVLHALLCLHRTLTSWLRVRFGTWNWIWRRCCRAASAAVLAPLGFTLRKPPAVGRNRRHHRHPRGGSCLAAAHHRMRWRADGRSLEKLPVHMGLVITEVEQEPSFSDIASLVVWCMAVGISYISVYDHQGIFKRNNSRLMDEILKQQQELLGLDCSKYSPEFANSNDKDDQVLNCHLAVKVLSPEDGKADIVRAAQDFCQLVAQKQKRPTDLDVDTLASLLSSNGCPDPDLVLKFGPVDSTLGFLPWHIRLTEIVSLPSHLNISYEDFFSALRQYAACEQRLGK", "length": 293 }, "evidence": [ { "id": "RGD:1307879", "url": "https://alliancegenome.org/gene/RGD:1307879#orthology", "database": "AGR" }, { "id": "MGI:1196365", "url": "https://alliancegenome.org/gene/MGI:1196365#orthology", "database": "AGR" }, { "id": "HGNC:21042", "url": "https://alliancegenome.org/gene/HGNC:21042#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040718-48", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040718-48#orthology", "database": "AGR" }, { "id": "FB:FBgn0031312", "url": "https://alliancegenome.org/gene/FB:FBgn0031312#orthology", "database": "AGR" }, { "id": "SGD:S000002352", "url": "https://alliancegenome.org/gene/SGD:S000002352#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99LJ8-1", "protein_name": "Dehydrodolichyl diphosphate synthase complex subunit Nus1", "gene_name": "Nus1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTGLYELVWRVLHALLCLHLTLTSWLRVRFGTWNWIWRRCCRAASAAVLAPLGFTLRKPRAVGRNRRHHRHPHGGPGPGPGPAATHPRLRWRADVRSLQKLPVHMGLLVTEEVQEPSFSDIASLVVWCMAVGISYISVYDHQGIFKRNNSRLMDEILKQQQELLGQDCSKYSAEFANSNDKDDQDLNCPSAVKVLSPEDGKADIVRAAQDFCQLVAQQQRKPTDLDVDLLGSLLSSHGFPDPDLVLKFGPVDSTLGFLPWQIRLTEIVSLPSHLNISYEDFFSALRQYAACEQRLGK", "length": 297 }, "evidence": [ { "id": "RGD:1307879", "url": "https://alliancegenome.org/gene/RGD:1307879#orthology", "database": "AGR" }, { "id": "MGI:1196365", "url": "https://alliancegenome.org/gene/MGI:1196365#orthology", "database": "AGR" }, { "id": "HGNC:21042", "url": "https://alliancegenome.org/gene/HGNC:21042#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040718-48", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040718-48#orthology", "database": "AGR" }, { "id": "FB:FBgn0031312", "url": "https://alliancegenome.org/gene/FB:FBgn0031312#orthology", "database": "AGR" }, { "id": "SGD:S000002352", "url": "https://alliancegenome.org/gene/SGD:S000002352#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q9VPX8", "url": "https://www.uniprot.org/uniprotkb/Q9VPX8" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VPX8", "url": "https://www.uniprot.org/uniprotkb/Q9VPX8" } ], "pmid": "" }, { "name": "dehydrodolichyl diphosphate synthase complex", "id": "GO:1904423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904423", "evidence": [ { "database": "UniProtKB", "id": "Q9VPX8", "url": "https://www.uniprot.org/uniprotkb/Q9VPX8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein secretion", "id": "GO:0009306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009306", "evidence": [ { "database": "UniProtKB", "id": "Q9VPX8", "url": "https://www.uniprot.org/uniprotkb/Q9VPX8" } ], "pmid": "" }, { "name": "dolichyl monophosphate biosynthetic process", "id": "GO:0043048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043048", "evidence": [ { "database": "UniProtKB", "id": "Q9VPX8", "url": "https://www.uniprot.org/uniprotkb/Q9VPX8" } ], "pmid": "" }, { "name": "dolichyl diphosphate biosynthetic process", "id": "GO:0006489", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006489", "evidence": [ { "database": "UniProtKB", "id": "Q9VPX8", "url": "https://www.uniprot.org/uniprotkb/Q9VPX8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity", "id": "GO:0045547", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045547", "evidence": [ { "database": "UniProtKB", "id": "Q9VPX8", "url": "https://www.uniprot.org/uniprotkb/Q9VPX8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 156, "end_pos": 158, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "53008", "name": "", "equation": "n isopentenyl diphosphate + (2E,6E)-farnesyl diphosphate = a di-trans,poly-cis-polyprenyl diphosphate + n diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9W3M6-1", "Q9VPX8-1" ], "evidence": [ { "id": "53008", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/53008" } ] }, { "id": "R-DME-4419978", "name": "DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane, cytoplasmic side of endoplasmic reticulum membrane", "input_participant_list": [ "R-ALL-191362", "R-ALL-4419987" ], "output_participant_list": [ "R-ALL-4419982" ], "enzyme_list": [ "Q9W3M6-1", "Q9VPX8-1" ], "evidence": [ { "id": "R-DME-4419978", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-4419978" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-191362", "participant_name": "IPPP [cytosol]", "crossref": [ { "id": "128769", "database": "ChEBI", "url": "" }, { "id": "C00129", "database": "COMPOUND", "url": "" }, { "id": "ZINC000008215654", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-4419982", "participant_name": "pPPP [cytoplasmic side of endoplasmic reticulum membrane]", "crossref": [ { "id": "136960", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-4419987", "participant_name": "E,E-FPP [cytosol]", "crossref": [ { "id": "175763", "database": "ChEBI", "url": "" }, { "id": "ZINC000012494625", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "Q9VPX8", "gene_name": "Tango14", "activity": [ { "ec_number": "2.5.1.87", "activity": "n isopentenyl diphosphate + (2E,6E)-farnesyl diphosphate = a di-trans,poly-cis-polyprenyl diphosphate + n diphosphate.", "evidence": [ { "id": "Q9VPX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPX8" } ] }, { "ec_number": "2.5.1.87", "activity": "", "evidence": [ { "id": "Q9VPX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPX8" } ] } ] }, { "uniprot_ac": "Q9W3M6", "gene_name": "Dhdds", "activity": [ { "ec_number": "2.5.1.-", "activity": "", "evidence": [ { "id": "Q9W3M6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3M6" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.5.1.87", "ec_name": "n isopentenyl diphosphate + (2E,6E)-farnesyl diphosphate = a di-trans,poly-cis-polyprenyl diphosphate + n diphosphate.", "evidence": [ { "id": "2.5.1.87", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.87" }, { "id": "2.5.1.87", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.5.1.87" } ] } ], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 156, "end_pos": 158 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VPZ5-1", "uniprot_ac": "Q9VPZ5", "uniprot_id": "Q9VPZ5_DROME", "mass": { "chemical_mass": 70935.0, "monoisotopic_mass": 70935.0 }, "refseq": { "ac": "NP_001259865", "name": "uncharacterized protein, isoform B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259865" }, "gene_names": [ { "name": "CT16527", "type": "recommended", "evidence": [ { "id": "Q9VPZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPZ5" } ] }, { "name": "CG5397", "type": "synonym", "evidence": [ { "id": "NP_001259865", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259865" }, { "id": "Q9VPZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPZ5" } ] }, { "name": "CT16527", "type": "synonym", "evidence": [ { "id": "NP_001259865", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259865" } ] }, { "name": "Dmel\\CG5397", "type": "synonym", "evidence": [ { "id": "NP_001259865", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259865" }, { "id": "Q9VPZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPZ5" } ] }, { "name": "Dmel_CG5397", "type": "synonym", "evidence": [ { "id": "Q9VPZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPZ5" } ] } ], "protein_names": [ { "name": "Carboxylesterase type B domain-containing protein", "type": "recommended", "evidence": [ { "id": "Q9VPZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPZ5/entry#names_and_taxonomy" } ] }, { "name": "CG5397-PB", "type": "synonym", "evidence": [ { "id": "NP_001259865", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259865" } ] }, { "name": "uncharacterized protein, isoform B", "type": "synonym", "evidence": [ { "id": "NP_001259865", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259865" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VPZ5", "url": "https://www.uniprot.org/uniprotkb/Q9VPZ5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "CT16527", "url": "https://www.uniprot.org/uniprotkb/Q9VPZ5", "locus": { "chromosome": "2L", "start_pos": 1243018, "end_pos": 1240036, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0031327", "url": "https://www.ensemblgenomes.org/id/FBgn0031327" } ] } } ], "crossref": [ { "id": "FB:FBgn0031327", "url": "https://alliancegenome.org/gene/FB:FBgn0031327", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0031327", "url": "https://bgee.org/?page=gene&gene_id=FBgn0031327", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0031327", "url": "https://flybase.org/reports/FBgn0031327", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "33313", "url": "https://www.ncbi.nlm.nih.gov/gene/33313", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VPZ5", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VPZ5*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR002018", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002018", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050309", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050309", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG5397", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG5397", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TRHGPPC", "url": "https://omabrowser.org/oma/group/TRHGPPC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VPZ5", "url": "https://www.orthodb.org/?gene=Q9VPZ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11559", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11559", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00135", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00135", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001259865", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259865", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VPZ5", "url": "https://www.uniprot.org/uniprotkb/Q9VPZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VPZ5-1", "url": "https://www.uniprot.org/uniprotkb/Q9VPZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQSQLKRNTLLLLLLSVVILASCKSGGDAHVRVKRIVGGKQSKAPPVDDPVIFARLFDRDARVEGFRNPSTGIYSFLGMHYAEPPVGPLRYSRPVYKRLAGDFNATKHGPPCIQPHPQFPQRIIGDEDCLLLNVYTPQMPDETTGLPVFVWIHPGGYRYGSAAQYDATPMAQRGAIVVAPQYRLGSLGIMGDGTKQFDGNLAMFDLAAALRWVTDYISYFGGNPKQVQAIGHGSGAASAMYLSMSPTSRSAGDVHGVVAMSGTALSQYAMDKEPVQSVQEVAKINGCPTGNELEIVNCLRSKSAEDIIKNDDKVQTERLAGRALVKGLTGNVGFQPHIESEDDGRALPSLIVGEPEQQLKSSNFSGIPLLTGVTKHETANSVTVETIEKVFGSAEQFLGSLSDSLNKLTSFLKIDKLTGQIAKPELPGLTSVLTPTLQDVWKVPQALNVDQVLSKVVESTTDVLFNLPAVLTTQVWSRLAPAFMYSFEYNGTKSKGINFLKGLPIVSETAHDKPETVGHGDEIGYMFDANDIFGNPMEETRLTSAEDLKVRNNLIDLLVKFANKDKEEGGKSSIFQSVTGKATPFIKIDTKLQTSNDFRFCELSVLGASLSPLSSTSCAGLGNLLGQLGSLGGGLGGTLGGVGSTLGLGGNGGGGKRGGLGLGIL", "length": 665, "header": "tr|Q9VPZ5-1|Q9VPZ5_DROME Isoform 1 of Carboxylesterase type B domain-containing protein OS=Drosophila melanogaster OX=7227 GN=CT16527 PE=1 SV=1 CANONICAL=Q9VPZ5-1" }, "isoforms": [ { "isoform_ac": "Q9VPZ5-1", "url": "https://www.uniprot.org/uniprotkb/Q9VPZ5/entry#Q9VPZ5-1", "sequence": { "sequence": "MQSQLKRNTLLLLLLSVVILASCKSGGDAHVRVKRIVGGKQSKAPPVDDPVIFARLFDRDARVEGFRNPSTGIYSFLGMHYAEPPVGPLRYSRPVYKRLAGDFNATKHGPPCIQPHPQFPQRIIGDEDCLLLNVYTPQMPDETTGLPVFVWIHPGGYRYGSAAQYDATPMAQRGAIVVAPQYRLGSLGIMGDGTKQFDGNLAMFDLAAALRWVTDYISYFGGNPKQVQAIGHGSGAASAMYLSMSPTSRSAGDVHGVVAMSGTALSQYAMDKEPVQSVQEVAKINGCPTGNELEIVNCLRSKSAEDIIKNDDKVQTERLAGRALVKGLTGNVGFQPHIESEDDGRALPSLIVGEPEQQLKSSNFSGIPLLTGVTKHETANSVTVETIEKVFGSAEQFLGSLSDSLNKLTSFLKIDKLTGQIAKPELPGLTSVLTPTLQDVWKVPQALNVDQVLSKVVESTTDVLFNLPAVLTTQVWSRLAPAFMYSFEYNGTKSKGINFLKGLPIVSETAHDKPETVGHGDEIGYMFDANDIFGNPMEETRLTSAEDLKVRNNLIDLLVKFANKDKEEGGKSSIFQSVTGKATPFIKIDTKLQTSNDFRFCELSVLGASLSPLSSTSCAGLGNLLGQLGSLGGGLGGTLGGVGSTLGLGGNGGGGKRGGLGLGIL", "length": 665, "header": "tr|Q9VPZ5-1|Q9VPZ5_DROME Isoform 1 of Carboxylesterase type B domain-containing protein OS=Drosophila melanogaster OX=7227 GN=CT16527 PE=1 SV=1 CANONICAL=Q9VPZ5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VPZ5", "url": "https://www.uniprot.org/uniprotkb/Q9VPZ5" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VPZ5", "url": "https://www.uniprot.org/uniprotkb/Q9VPZ5" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPZ5", "url": "https://www.uniprot.org/uniprotkb/Q9VPZ5" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPZ5", "url": "https://www.uniprot.org/uniprotkb/Q9VPZ5" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VPZ5", "url": "https://www.uniprot.org/uniprotkb/Q9VPZ5" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VPZ5", "url": "https://www.uniprot.org/uniprotkb/Q9VPZ5" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VPZ5", "url": "https://www.uniprot.org/uniprotkb/Q9VPZ5" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPZ5", "url": "https://www.uniprot.org/uniprotkb/Q9VPZ5" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VPZ5", "url": "https://www.uniprot.org/uniprotkb/Q9VPZ5" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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Pseudouridine-5'-phosphatase OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG5561 PE=4 SV=1 CANONICAL=Q9VQ02-1" }, "isoforms": [ { "isoform_ac": "Q9VQ02-1", "url": "https://www.uniprot.org/uniprotkb/Q9VQ02/entry#Q9VQ02-1", "sequence": { "sequence": "MCTFGCRTCKSQPDCEGCSPKCCSPCISYCIFDLESAVFDTRHVYRKALKELVRCYDKRIPDILHVQSGPMTISEMSELFCRKLDIPMSWESFRYELNERTSHLIANPPFMDGIERLVPHLRNSCMELGLITSSNEANYCSKIRGREDFFENFSTVVCADDPELRAPKPEPDVYLIAMSRLGDAGPDCTLVFDGTPKGVQAASDARLPVIMLAEKDLPCCWSELAALRFEYLDDFEPEMYNLPPFTDPAPKRRSSRRRTRYSQRLTVIRARAAEAAAAEEAEAEEEEPAEPPPPAALPSILNLRE", "length": 305, "header": "tr|Q9VQ02-1|Q9VQ02_DROME Isoform 1 of Pseudouridine-5'-phosphatase OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG5561 PE=4 SV=1 CANONICAL=Q9VQ02-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, 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"title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ02", "url": "https://www.uniprot.org/uniprotkb/Q9VQ02" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ02", "url": "https://www.uniprot.org/uniprotkb/Q9VQ02" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ02", "url": "https://www.uniprot.org/uniprotkb/Q9VQ02" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ02", "url": "https://www.uniprot.org/uniprotkb/Q9VQ02" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ02", "url": "https://www.uniprot.org/uniprotkb/Q9VQ02" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ02", "url": "https://www.uniprot.org/uniprotkb/Q9VQ02" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ02", "url": "https://www.uniprot.org/uniprotkb/Q9VQ02" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ02", "url": "https://www.uniprot.org/uniprotkb/Q9VQ02" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ02", "url": "https://www.uniprot.org/uniprotkb/Q9VQ02" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG5561", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG5561", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1N669-1", "protein_name": "Pseudouridine-5'-phosphatase", "gene_name": "pudp", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSYKPVTHVLFDMDGLLLDTERLYTVSFQEVCDRFNKQYTWEVKSSVMGKKALDAARIIRDKIGLPMTPEELLEETRKIQERLFPTTSLLPGVEKLVNHLHKHGIPIAVGTSSAGLTFEMKTSRHKEFFSLFSHIVLGDDPDVKNGKPLPDTFLVCAKRFSPPANPKQCLVFEDAPNGVKAGLAAGMQVVMIPDDNLDRSLTQEATLLLRSMEDFRPELFGLPAYA", "length": 226 }, "evidence": [ { "id": "MGI:1914615", "url": "https://alliancegenome.org/gene/MGI:1914615#orthology", "database": "AGR" }, { "id": "HGNC:16818", "url": "https://alliancegenome.org/gene/HGNC:16818#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050522-36", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-36#orthology", "database": "AGR" }, { "id": "RGD:1305101", "url": 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"MAAPPQPVTHLIFDMDGLLLDTERLYSVVFQEICNRYDKKYSWDVKSLVMGKKALEAAQIIIDVLQLPMSKEELVEESQTKLKEVFPTAALMPGAEKLIIHLRKHGIPFALATSSGSASFDMKTSRHKEFFSLFSHIVLGDDPEVQHGKPDPDIFLACAKRFSPPPAMEKCLVFEDAPNGVEAALAAGMQVVMVPDGNLSRDLTTKATLVLNSLQDFQPELFGLPSYE", "length": 228 }, "evidence": [ { "id": "MGI:1914615", "url": "https://alliancegenome.org/gene/MGI:1914615#orthology", "database": "AGR" }, { "id": "HGNC:16818", "url": "https://alliancegenome.org/gene/HGNC:16818#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050522-36", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-36#orthology", "database": "AGR" }, { "id": "RGD:1305101", "url": "https://alliancegenome.org/gene/RGD:1305101#orthology", "database": "AGR" }, { "id": "FB:FBgn0031333", "url": "https://alliancegenome.org/gene/FB:FBgn0031333#orthology", "database": "AGR" }, { "id": "SGD:S000007242", "url": "https://alliancegenome.org/gene/SGD:S000007242#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q86ZR7-1", "protein_name": "Probable pseudouridine-5'-phosphatase YKL033W-A", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTHPVAVKACLFDMDGLLINTEDIYTETLNETLAEFGKGPLTWDVKIKLQGLPGPEAGKRVIEHYKLPITLDEYDERNVALQSLKWGTCEFLPGALNLLKYLKLKNIPIALCTSSNKTKFRGKTSHLEEGFDLFDTIVTGDDPRIAKGRGKPFPDIWQLGLKELNEKFHTDIKPDECIVFEDGIPGVKSAKAFGAHVIWVPHPEAHAVLGDTEALLAGKGELLSSLEKLEMSKYGL", "length": 236 }, "evidence": [ { "id": "MGI:1914615", "url": "https://alliancegenome.org/gene/MGI:1914615#orthology", "database": "AGR" }, { "id": "HGNC:16818", "url": "https://alliancegenome.org/gene/HGNC:16818#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050522-36", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-36#orthology", "database": "AGR" }, { "id": "RGD:1305101", "url": "https://alliancegenome.org/gene/RGD:1305101#orthology", "database": "AGR" }, { "id": "FB:FBgn0031333", "url": 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"https://alliancegenome.org/gene/HGNC:16818#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050522-36", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-36#orthology", "database": "AGR" }, { "id": "RGD:1305101", "url": "https://alliancegenome.org/gene/RGD:1305101#orthology", "database": "AGR" }, { "id": "FB:FBgn0031333", "url": "https://alliancegenome.org/gene/FB:FBgn0031333#orthology", "database": "AGR" }, { "id": "SGD:S000007242", "url": "https://alliancegenome.org/gene/SGD:S000007242#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VQ01-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG5556", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MCSACCKSCKAPPGCSLCPPMCCSPGISYCIFDLESAVFDTRHVYKRAVIELAASYNKIIPEAVLIKSGPMETAEMAELICRKCDLPVSWESFRFQLNERTSDLIANPTLMPGVERLVTHLGRCCMGLGLITSCSESMYCTKIRDREDFFQNFSSVICADDADLKAPKPEPDVYLIAMRRLGDAGPDCTLVFDGTPKGVQAATDARLPVVMLAEKDLPCCWSELATLRLETLEEFDPAEFNMPPYSCTEPPPKKPKASSHRSSQKSAGSQRGSAALKKAAADSEADEGEEEEGEGQEVA", "length": 299 }, "evidence": [ { "id": "MGI:1914615", "url": "https://alliancegenome.org/gene/MGI:1914615#orthology", "database": "AGR" }, { "id": "HGNC:16818", "url": "https://alliancegenome.org/gene/HGNC:16818#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050522-36", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-36#orthology", "database": "AGR" }, { "id": "RGD:1305101", "url": "https://alliancegenome.org/gene/RGD:1305101#orthology", "database": "AGR" }, { "id": "SGD:S000007242", "url": "https://alliancegenome.org/gene/SGD:S000007242#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VQ04-1", "protein_name": "Uncharacterized protein", "gene_name": "28557659", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPTKKCYCPVTHVIFDCDGTLIDSEGIYLKTVQDLLAKYGKTYTKVDQTQHMGMPVGTFSQHIVKDLKLPLSPAEFQKEFEAAVDKSMGSVALLPGVRDLILHLHEYRIPFCIATSSFRKLFKVKAESFKDIFLAFHHVVCGDDPALGPGRGKPYPDIYLLAASRFNPPADPKKCLIFEDAPVGLIGGKAAGSQVIFIPTDNVSKQQKKGATMVLKSMADFKPELFGLPPFDTCSKFEFG", "length": 240 }, "evidence": [ { "id": "MGI:1914615", "url": "https://alliancegenome.org/gene/MGI:1914615#orthology", "database": "AGR" }, { "id": "HGNC:16818", "url": "https://alliancegenome.org/gene/HGNC:16818#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050522-36", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-36#orthology", "database": "AGR" }, { "id": "RGD:1305101", "url": "https://alliancegenome.org/gene/RGD:1305101#orthology", "database": "AGR" }, { "id": "SGD:S000007242", "url": "https://alliancegenome.org/gene/SGD:S000007242#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "phosphatase activity", "id": "GO:0016791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016791", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ02", "url": "https://www.uniprot.org/uniprotkb/Q9VQ02" } ], "pmid": "" }, { "name": "pseudouridine 5'-phosphatase activity", "id": "GO:1990738", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990738", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ02", "url": "https://www.uniprot.org/uniprotkb/Q9VQ02" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 152, "end_pos": 154, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VQ27-1", "uniprot_ac": "Q9VQ27", "uniprot_id": "Q9VQ27_DROME", "mass": { "chemical_mass": 28993.0, "monoisotopic_mass": 28993.0 }, "refseq": { "ac": "NP_608609", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608609" }, "gene_names": [ { "name": "Dmel\\CG14352", "type": "recommended", "evidence": [ { "id": "Q9VQ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQ27" } ] }, { "name": "CG14352", "type": "synonym", "evidence": [ { "id": "NP_608609", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608609" }, { "id": "Q9VQ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQ27" } ] }, { "name": "Dmel\\CG14352", "type": "synonym", "evidence": [ { "id": "NP_608609", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608609" } ] }, { "name": "Dmel_CG14352", "type": "synonym", "evidence": [ { "id": "Q9VQ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQ27" } ] } ], "protein_names": [ { "name": "Regulatory protein zeste", "type": "recommended", "evidence": [ { "id": "Q9VQ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQ27/entry#names_and_taxonomy" } ] }, { "name": "CG14352-PA", "type": "synonym", "evidence": [ { "id": "NP_608609", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608609" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_608609", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608609" } ] } ], "function": [ { "annotation": "Involved in transvection phenomena (= synapsis-dependent gene expression), where the synaptic pairing of chromosomes carrying genes with which zeste interacts influences the expression of these genes. Zeste binds to DNA and stimulates transcription from a nearby promoter.", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ27", "url": "https://www.uniprot.org/uniprotkb/Q9VQ27#function" }, { "database": "UniProtKB", "id": "ARBA00025466", "url": "https://www.uniprot.org/uniprotkb/ARBA00025466#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VQ27", "url": "https://www.uniprot.org/uniprotkb/Q9VQ27" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG14352", "url": "https://www.uniprot.org/uniprotkb/Q9VQ27", "locus": { "chromosome": "2L", "start_pos": 1612576, "end_pos": 1611410, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0031351", "url": "https://www.ensemblgenomes.org/id/FBgn0031351" } ] } } ], "crossref": [ { "id": "FB:FBgn0031351", "url": "https://alliancegenome.org/gene/FB:FBgn0031351", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0031351", "url": "https://bgee.org/?page=gene&gene_id=FBgn0031351", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0031351", "url": "https://flybase.org/reports/FBgn0031351", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "33341", "url": "https://www.ncbi.nlm.nih.gov/gene/33341", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VQ27", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VQ27*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR028002", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028002", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG14352", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG14352", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YRCENAR", "url": "https://omabrowser.org/oma/group/YRCENAR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VQ27", "url": "https://www.orthodb.org/?gene=Q9VQ27", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF13873", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13873", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_608609", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608609", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VQ27", "url": "https://www.uniprot.org/uniprotkb/Q9VQ27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VQ27-1", "url": "https://www.uniprot.org/uniprotkb/Q9VQ27-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFAAKRVRARAKNFTIEEEEILENLILAHRDVIRNKQKDPAIWRKKSEAWKQIEADFAIQTGIERSWQALREKYTNNLRMMRKNGTLSDEEAKTDNASDSVQNLSISGVSSLAAAADNEESSTYFESELNRKSLRSASTEVKLVPNNSSYSVDRPNYSALNVNEESVDVSSEEDATNTLKDEKVVLIRLQQEYYRCENARAAEKHKLEMEKQKYELEQRKVELRNMRLKNELLEAEILEKRRKVAQSKASS", "length": 251, "header": "tr|Q9VQ27-1|Q9VQ27_DROME Isoform 1 of Regulatory protein zeste OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG14352 PE=1 SV=1 CANONICAL=Q9VQ27-1" }, "isoforms": [ { "isoform_ac": "Q9VQ27-1", "url": "https://www.uniprot.org/uniprotkb/Q9VQ27/entry#Q9VQ27-1", "sequence": { "sequence": "MFAAKRVRARAKNFTIEEEEILENLILAHRDVIRNKQKDPAIWRKKSEAWKQIEADFAIQTGIERSWQALREKYTNNLRMMRKNGTLSDEEAKTDNASDSVQNLSISGVSSLAAAADNEESSTYFESELNRKSLRSASTEVKLVPNNSSYSVDRPNYSALNVNEESVDVSSEEDATNTLKDEKVVLIRLQQEYYRCENARAAEKHKLEMEKQKYELEQRKVELRNMRLKNELLEAEILEKRRKVAQSKASS", "length": 251, "header": "tr|Q9VQ27-1|Q9VQ27_DROME Isoform 1 of Regulatory protein zeste OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG14352 PE=1 SV=1 CANONICAL=Q9VQ27-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ27", "url": "https://www.uniprot.org/uniprotkb/Q9VQ27" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ27", "url": "https://www.uniprot.org/uniprotkb/Q9VQ27" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ27", "url": "https://www.uniprot.org/uniprotkb/Q9VQ27" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ27", "url": "https://www.uniprot.org/uniprotkb/Q9VQ27" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ27", "url": "https://www.uniprot.org/uniprotkb/Q9VQ27" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ27", "url": "https://www.uniprot.org/uniprotkb/Q9VQ27" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ27", "url": "https://www.uniprot.org/uniprotkb/Q9VQ27" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ27", "url": "https://www.uniprot.org/uniprotkb/Q9VQ27" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ27", "url": "https://www.uniprot.org/uniprotkb/Q9VQ27" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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{ "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 147, "end_pos": 149, "annotation": "n_glycosylation_sequon" }, { "start_pos": 156, "end_pos": 158, "annotation": "n_glycosylation_sequon" }, { "start_pos": 84, "end_pos": 86, "annotation": "n_glycosylation_sequon" }, { "start_pos": 96, "end_pos": 98, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VQ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQ27" }, { "id": "PF13873", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13873" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Myb/SANT-like DNA-binding", "eco_id": "ECO_0000259", "start_pos": 10, "end_pos": 84, "start_aa": "Arg", "end_aa": "Asn", "glycosite_overlap": "" } 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"MISIAQLLTSFTAGALASAQAIRFLKTANEEESPAKISSQLETAVIDGLATEQPKILGSEQISNVMQHILSSERNASGVYLDAMHNRSANKQEYALGSESLNQMLEDIMTPAGSVSSRSLSMEPAVEA", "length": 128, "header": "tr|Q9VQ43-1|Q9VQ43_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=BcDNA:GH02930 PE=4 SV=1 CANONICAL=Q9VQ43-1" }, "isoforms": [ { "isoform_ac": "Q9VQ43-1", "url": "https://www.uniprot.org/uniprotkb/Q9VQ43/entry#Q9VQ43-1", "sequence": { "sequence": "MISIAQLLTSFTAGALASAQAIRFLKTANEEESPAKISSQLETAVIDGLATEQPKILGSEQISNVMQHILSSERNASGVYLDAMHNRSANKQEYALGSESLNQMLEDIMTPAGSVSSRSLSMEPAVEA", "length": 128, "header": "tr|Q9VQ43-1|Q9VQ43_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=BcDNA:GH02930 PE=4 SV=1 CANONICAL=Q9VQ43-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ43", "url": "https://www.uniprot.org/uniprotkb/Q9VQ43" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ43", "url": "https://www.uniprot.org/uniprotkb/Q9VQ43" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ43", "url": "https://www.uniprot.org/uniprotkb/Q9VQ43" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ43", "url": "https://www.uniprot.org/uniprotkb/Q9VQ43" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ43", "url": "https://www.uniprot.org/uniprotkb/Q9VQ43" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ43", "url": "https://www.uniprot.org/uniprotkb/Q9VQ43" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ43", "url": "https://www.uniprot.org/uniprotkb/Q9VQ43" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ43", "url": "https://www.uniprot.org/uniprotkb/Q9VQ43" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ43", "url": "https://www.uniprot.org/uniprotkb/Q9VQ43" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG7289", "url": "https://www.uniprot.org/uniprotkb/Q9VQ60", "locus": { "chromosome": "2L", "start_pos": 1984514, "end_pos": 1982217, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0031379", "url": "https://www.ensemblgenomes.org/id/FBgn0031379" } ] } } ], "crossref": [ { "id": "FB:FBgn0031379", "url": "https://alliancegenome.org/gene/FB:FBgn0031379", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0031379", "url": "https://bgee.org/?page=gene&gene_id=FBgn0031379", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0031379", "url": "https://flybase.org/reports/FBgn0031379", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "33372", "url": "https://www.ncbi.nlm.nih.gov/gene/33372", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VQ60", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VQ60*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR018795", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018795", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG7289", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG7289", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HLECNMH", "url": "https://omabrowser.org/oma/group/HLECNMH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VQ60", "url": "https://www.orthodb.org/?gene=Q9VQ60", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31386", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31386", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31386:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31386:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10222", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10222", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_608635", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608635", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VQ60", "url": "https://www.uniprot.org/uniprotkb/Q9VQ60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VQ60-1", "url": "https://www.uniprot.org/uniprotkb/Q9VQ60-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLFRSAKSKFDAGDVMRRMKRLAEGTISSYRRLFLLLLCVCVVFYMIPPIFRYIFLSAPEQKDPHSMCMDDRLTPFILQNFEFDANIRHVSPAKMPGERDFTPYVGNGYLGLEIAHDAFLNIKNGRAMQLPIPFQPVVSVSGGSASGGEKEATVVEYLTGMVHRFQCFAGYFVSYTYYAHRTQPNIFMQELQITNTRNLLEDIELIMPRVNLQKLTRRTVPLSEPVSVGVFTYTELEVLSGTVQLQAENPSKSIVISIVKPQMDSKLQLRKRGTVRIVYPTAVHYSKPVAEEKIGGISETIEQQATQAMAKLLQKLGSKPSNPGSLNSVNIYRQEHIDVWTDLWATGFTISTSKAENSLNGDRINATMYAVLSQVRSFEFEEAGGSKKEDIAKALTYAEGCYDSYHTLQAENLWREMSNLQQLNSLVTSWMLTLEKQGCHNLIRAGASGVIQAMVLSFGSFRFSNQHLECNIHPKFLHRDFHFRRLNYGNKTHVNVTIIVDDDNKAVINIALDRSDRSYYACDGGCLDEPVLLTQNRRQFPVKLTEPLTAILYITEDKQHMEELHHAIHVKEVVEAPAHEQHLIALHRHGHQLGGLPTLFWVSVCAIIIVFHIFLCKLIIKEYCEPSDKLRYRYNKP", "length": 637, "header": "tr|Q9VQ60-1|Q9VQ60_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG7289 PE=4 SV=2 CANONICAL=Q9VQ60-1" }, "isoforms": [ { "isoform_ac": "Q9VQ60-1", "url": "https://www.uniprot.org/uniprotkb/Q9VQ60/entry#Q9VQ60-1", "sequence": { "sequence": "MLFRSAKSKFDAGDVMRRMKRLAEGTISSYRRLFLLLLCVCVVFYMIPPIFRYIFLSAPEQKDPHSMCMDDRLTPFILQNFEFDANIRHVSPAKMPGERDFTPYVGNGYLGLEIAHDAFLNIKNGRAMQLPIPFQPVVSVSGGSASGGEKEATVVEYLTGMVHRFQCFAGYFVSYTYYAHRTQPNIFMQELQITNTRNLLEDIELIMPRVNLQKLTRRTVPLSEPVSVGVFTYTELEVLSGTVQLQAENPSKSIVISIVKPQMDSKLQLRKRGTVRIVYPTAVHYSKPVAEEKIGGISETIEQQATQAMAKLLQKLGSKPSNPGSLNSVNIYRQEHIDVWTDLWATGFTISTSKAENSLNGDRINATMYAVLSQVRSFEFEEAGGSKKEDIAKALTYAEGCYDSYHTLQAENLWREMSNLQQLNSLVTSWMLTLEKQGCHNLIRAGASGVIQAMVLSFGSFRFSNQHLECNIHPKFLHRDFHFRRLNYGNKTHVNVTIIVDDDNKAVINIALDRSDRSYYACDGGCLDEPVLLTQNRRQFPVKLTEPLTAILYITEDKQHMEELHHAIHVKEVVEAPAHEQHLIALHRHGHQLGGLPTLFWVSVCAIIIVFHIFLCKLIIKEYCEPSDKLRYRYNKP", "length": 637, "header": "tr|Q9VQ60-1|Q9VQ60_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG7289 PE=4 SV=2 CANONICAL=Q9VQ60-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ60", "url": "https://www.uniprot.org/uniprotkb/Q9VQ60" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ60", "url": "https://www.uniprot.org/uniprotkb/Q9VQ60" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ60", "url": "https://www.uniprot.org/uniprotkb/Q9VQ60" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ60", "url": "https://www.uniprot.org/uniprotkb/Q9VQ60" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ60", "url": "https://www.uniprot.org/uniprotkb/Q9VQ60" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ60", "url": "https://www.uniprot.org/uniprotkb/Q9VQ60" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ60", "url": "https://www.uniprot.org/uniprotkb/Q9VQ60" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ60", "url": "https://www.uniprot.org/uniprotkb/Q9VQ60" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ60", "url": "https://www.uniprot.org/uniprotkb/Q9VQ60" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ60", "url": "https://www.uniprot.org/uniprotkb/Q9VQ60" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ60", "url": "https://www.uniprot.org/uniprotkb/Q9VQ60" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG7289", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG7289", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AC58G7Z5-1", "protein_name": "Uncharacterized protein KIAA2013 homolog isoform X1", "gene_name": "si:dkeyp-104h9.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFNPPKSIWSKRQIMWLQQRLKGLPSLLSSSWARRVLVGLLVFLIFYYWFLSSDGLLKLFSMSREPGGAAGVCLQTDLHRWVSMADRGDGVVHTPQTKESGTFVVGNGHFLVDVDSNKLWVASSTQPGSAPVHQTDYSPIARLQVPGTRSEAQAMMLWYRKGSVLSSRCFQTAKSQSSRDCIVIREEFIAHRSRHNVHLQRILISNPTDHMVSVDMSLESLSFRSKMEKMDDKEFAVSSGRVLTEKKDTVLVVVATNRISNKIQVPSKSEYSANLVSVIHTSEPTEGGKLDDTLDKLRDRVRKEMVDVLRVDVEELMQEHQQAWVDLFISGVEIRKITDAHTPSSRTVNNTLYYILSTSTAPLLDQSLTSEDHEHLESSLNYADHCFSGHATMHAENLWPERLTNVAQILQLVNLWNLTLQKRGCKVLVAAGTHGMMQGMVLSFGGLQFTENHLQFQADPDVLHNSYSLRGIHYNKDLINLAVLQDIEGKPFLHVSVKPQEKPVKLYACEAGCMNEPVELTSELKGHTFPVMVTQPITPLLYISTDLTHLQDLRHTMHVKAILAHEDHMAKQYPGLPFLFWFSVASLITLFHFFLFKLIYNEYCGPGAKPLFRSKDDASV", "length": 620 }, "evidence": [ { "id": "HGNC:28513", "url": "https://alliancegenome.org/gene/HGNC:28513#orthology", "database": "AGR" }, { "id": "MGI:1924284", "url": "https://alliancegenome.org/gene/MGI:1924284#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZLT7-1", "protein_name": "RIKEN cDNA 2510039O18 gene like", "gene_name": "2510039O18Rikl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWLQQRLKGLPGLLSSSWARRLLCLLGLLLLLLWFASSGARRAAGGLHLPSWARSEPGAAEPSACLEAATRAWRGLRDRGEAVPLGPGVPALVANGFLALDAANNRLWVTPGEREPAVTPDFVPFVQLRPLNVVAEAGEAVLLLREGLLRRVRCLQLGTPGSGPAAGVPGPASASGLSTGSGRDCVLLQEDFLAHRGRPHVYLQRIQLNNPTERVAAFQTVGPTSGPVPKSFTSTLEKVGDHQFLLYSGRSTPLPSGLVHLVVVTSKKLVNRLQVAPKTQMDETVLWVVHVSAPIHPQVLKSKGTKELKALQDLARKEMLELLEMPASELLQDHQYLWAQLFSPGVEMKRITDAHTPSGLTVNLTLYYMLSCSPAPLLSPSLSHRERDQMEATLNYEDHCFSGHATMHAENLWPGQLSSVQQILQLADLWKLTLQKRGCKGLVKVGAPGILQGMVLSFGGLQFTENHLQFQADPEVLHNSYALHGIRYKNDHISLAVLADAEGKPYLHVSLESRGQPVKIYACEAGCLHDPVELTSEPGGHTFSVMVTQPITPLLYISTDLTHLQDLRHTLHLKAILAHDEHMAQQDPGLPFLFWFSVASLITLFHLFLFKLIYNEYCGPGAKPLFRSKEDPSV", "length": 634 }, "evidence": [ { "id": "HGNC:28513", "url": "https://alliancegenome.org/gene/HGNC:28513#orthology", "database": "AGR" }, { "id": "MGI:1924284", "url": "https://alliancegenome.org/gene/MGI:1924284#orthology", "database": "AGR" }, { "id": "RGD:1305350", "url": "https://alliancegenome.org/gene/RGD:1305350#orthology", "database": "AGR" }, { "id": "FB:FBgn0031379", "url": "https://alliancegenome.org/gene/FB:FBgn0031379#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8IYS2-1", "protein_name": "Uncharacterized protein KIAA2013", "gene_name": "KIAA2013", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWLQQRLKGLPGLLSSSWARRLLCLLGLLLLLLWFGGSGARRAAGGLHLLPWSRGEPGAAEPSACLEAATRAWRGLRERGEVVPLGPGVPALVANGFLALDVAANRLWVTPGEREPAVAPDFVPFVQLRPLSALAEAGEAVLLLREGLLRRVRCLQLGSPGPGPVAAGPGPASVSGLAAGSGRDCVLLQEDFLAHRGRPHVYLQRIQLNNPTERVAALQTVGPTAGPAPKAFTSTLEKVGDHQFLLYSGRSPPTPTGLVHLVVVAAKKLVNRLQVAPKTQLDETVLWVVHVSGPINPQVLKSKAAKELKALQDLARKEMLELLDMPAAELLQDHQLLWAQLFSPGVEMKKITDTHTPSGLTVNLTLYYMLSCSPAPLLSPSLSHRERDQMESTLNYEDHCFSGHATMHAENLWPGRLSSVQQILQLSDLWRLTLQKRGCKGLVKVGAPGILQGMVLSFGGLQFTENHLQFQADPDVLHNSYALHGIRYKNDHINLAVLADAEGKPYLHVSVESRGQPVKIYACKAGCLDEPVELTSAPTGHTFSVMVTQPITPLLYISTDLTHLQDLRHTLHLKAILAHDEHMAQQDPGLPFLFWFSVASLITLFHLFLFKLIYNEYCGPGAKPLFRSKEDPSV", "length": 634 }, "evidence": [ { "id": "HGNC:28513", "url": "https://alliancegenome.org/gene/HGNC:28513#orthology", "database": "AGR" }, { "id": "MGI:1924284", "url": "https://alliancegenome.org/gene/MGI:1924284#orthology", "database": "AGR" }, { "id": "RGD:1305350", "url": "https://alliancegenome.org/gene/RGD:1305350#orthology", "database": "AGR" }, { "id": "FB:FBgn0031379", "url": "https://alliancegenome.org/gene/FB:FBgn0031379#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q91X21-1", "protein_name": "Uncharacterized protein KIAA2013", "gene_name": "Kiaa2013", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWLQQRLKGLPGLLSSSWARRLLCLLGLLVLLLWFASSGARRAAGGLHLPSWARSEPGAAEPSACLEAATRAWRGLRDRGEAVPLGPGVPALVANGFLALDASNNRLWVTPGEREPAVTPDFVPFVQLRPLNVVAEAGEAVLLLREGLLRRVRCLQLGTPGSGPAAGVPGPASASGLSAGSGRDCVLLQEDFLAHRGRPHVYLQRIQLNNPTERVAALQTVGPTAGPVPKSFTSTLEKVGDHQFLLYSGRSTPLPSGLVHLVVVTSKKLVNRLQVAPKTQLDETVLWVVHISGPIHPQVLKSKGAKELKALQDLARKEMLELLEMPASELLQDHQYLWAQLFSPGVEMKRITDAHTPSGLTVNLTLYYMLSCSPAPLLSPSLSHREREQMEATLNYEDHCFSGHATMHAENLWPGQLSSVQQILQLADLWKLTLQKRGCKGLVKVGAPGILQGMVLSFGGLQFTENHLQFQADPEVLHNSYALHGIRYKNDHINLAVLVDAEGKPYLHVSLESRGQPVKIYACEAGCLHDPVELTSEPGGHTFSVMVTQPITPLLYISTDLTHLQDLRHTLHLKAILAHDEHMAQQDPGLPFLFWFSVASLITLFHLFLFKLIYNEYCGPGAKPLFRSKEDPSV", "length": 634 }, 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A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ95", "url": "https://www.uniprot.org/uniprotkb/Q9VQ95" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ95", "url": "https://www.uniprot.org/uniprotkb/Q9VQ95" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ95", "url": 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SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ95", "url": "https://www.uniprot.org/uniprotkb/Q9VQ95" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ95", "url": "https://www.uniprot.org/uniprotkb/Q9VQ95" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VQ95", "url": "https://www.uniprot.org/uniprotkb/Q9VQ95" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VQB6-1", "uniprot_ac": "Q9VQB6", "uniprot_id": "ATX7_DROME", "mass": { "chemical_mass": 104206.0, "monoisotopic_mass": 104206.0 }, "refseq": { "ac": "NP_001259932", "name": "ataxin 7, isoform C", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259932" }, "gene_names": [ { "name": "Atxn7", "type": "recommended", "evidence": [ { "id": "Q9VQB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQB6" } ] }, { "name": "Ataxin7", "type": "synonym", "evidence": [ { "id": "NP_001259932", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259932" } ] }, { "name": "Atxn7", "type": "synonym", "evidence": [ { "id": "NP_001259932", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259932" } ] }, { "name": "CG9866", "type": "synonym", "evidence": [ { "id": "NP_001259932", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259932" }, { "id": "Q9VQB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQB6" } ] }, { "name": "Dmel\\CG9866", "type": "synonym", "evidence": [ { "id": "NP_001259932", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259932" } ] }, { "name": "ataxin-7", "type": "synonym", "evidence": [ { "id": "NP_001259932", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259932" } ] }, { "name": "dATXN7", "type": "synonym", "evidence": [ { "id": "NP_001259932", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259932" } ] } ], "protein_names": [ { "name": "Ataxin-7", "type": "recommended", "evidence": [ { "id": "Q9VQB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQB6/entry#names_and_taxonomy" } ] }, { "name": "Ataxin-7", "type": "synonym", "evidence": [ { "id": "NP_001259932", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259932" } ] }, { "name": "Atxn7-PC", "type": "synonym", "evidence": [ { "id": "NP_001259932", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259932" } ] }, { "name": "CG9866-PC", "type": "synonym", "evidence": [ { "id": "NP_001259932", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259932" } ] }, { "name": "ataxin 7, isoform C", "type": "synonym", "evidence": [ { "id": "NP_001259932", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259932" } ] } ], "function": [ { "annotation": "Component of the transcription regulatory complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination (PubMed:20008933, PubMed:21764853, PubMed:24493646, PubMed:30559249). Acts as a tether connecting the not/nonstop-containing deubiquitinase (DUB) module to the rest of the SAGA complex; regulates DUB module specificity (PubMed:24493646, PubMed:31348003). Important for regulating deubiquitination of histone 2B by SAGA (PubMed:24493646). The SAGA complex predominantly acetylates histone H3 (PubMed:30559249). Important regulator of transcription during embryogenesis; required for nuclear anchoring and cellularization (PubMed:28887412). Tethering the DUB module prevents not/non-stop from stabilizing SCAR, preventing its ability to promote actin polymerization (PubMed:31348003).", "evidence": [ { "database": "UniProtKB", "id": "Q9VQB6", "url": "https://www.uniprot.org/uniprotkb/Q9VQB6#function" }, { "database": "PubMed", "id": "30559249", "url": "https://glygen.org/publication/PubMed/30559249" }, { "database": "PubMed", "id": "24493646", "url": "https://glygen.org/publication/PubMed/24493646" }, { "database": "PubMed", "id": "21764853", "url": "https://glygen.org/publication/PubMed/21764853" }, { "database": "PubMed", "id": "20008933", "url": "https://glygen.org/publication/PubMed/20008933" }, { "database": "PubMed", "id": "28887412", "url": "https://glygen.org/publication/PubMed/28887412" }, { "database": "PubMed", "id": "31348003", "url": "https://glygen.org/publication/PubMed/31348003" } ] } ], "disease": [ { "disease_id": "DOID:0050958", "recommended_name": { "id": "DOID:0050958", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050958", "name": "spinocerebellar ataxia 7", "description": "An autosomal dominant cerebellar ataxia that is characterized by ataxia, progressive vision loss, and failure to thrive, has_material_basis_in mutation in the ATXN7 gene." }, "synonyms": [ { "id": "MONDO:0016163", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016163", "name": "spinocerebellar ataxia 7", "description": "" }, { "id": "MONDO:0016163", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016163", "name": "ADCA2", "description": "" }, { "id": "MONDO:0016163", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016163", "name": "ADCAII", "description": "" }, { "id": "MONDO:0016163", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016163", "name": "ATXN7 autosomal dominant cerebellar ataxia type II", "description": "" }, { "id": "MONDO:0016163", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016163", "name": "SCA7", "description": "" }, { "id": "MONDO:0016163", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016163", "name": "ataxia with pigmentary retinopathy", "description": "" }, { "id": "MONDO:0016163", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016163", "name": "autosomal dominant cerebellar ataxia type 2", "description": "" }, { "id": "MONDO:0016163", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016163", "name": "autosomal dominant cerebellar ataxia type II", "description": "" }, { "id": "MONDO:0016163", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016163", "name": "autosomal dominant cerebellar ataxia type II caused by mutation in ATXN7", "description": "" }, { "id": "MONDO:0016163", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016163", "name": "cerebellar syndrome-pigmentary maculopathy syndrome", "description": "" }, { "id": "MONDO:0016163", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016163", "name": "spinocerebellar ataxia 7", "description": "" }, { "id": "MONDO:0016163", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016163", "name": "spinocerebellar ataxia type 7", "description": "" }, { "id": "MONDO:0016163", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016163", "name": "ADCA, type II", "description": "" }, { "id": "MONDO:0016163", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016163", "name": "OPCA III", "description": "" }, { "id": "MONDO:0016163", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016163", "name": "OPCA3", "description": "" }, { "id": "MIM:164500", "resource": "MIM", "url": "https://www.omim.org/entry/164500", "name": "Spinocerebellar ataxia 7", "description": "Spinocerebellar ataxia 7" } ], "unlinked_id_list": [], "evidence": [ { "id": "0050958", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050958" } ] }, { "disease_id": "DOID:1289", "recommended_name": { "id": "DOID:1289", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons." }, "synonyms": [ { "id": "DOID:1289", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1289", "name": "degenerative disease", "description": "" } ], "unlinked_id_list": [ "DOID:0112328", "DOID:0050953", "DOID:0111828", "DOID:0050765", "DOID:681", "DOID:0112322" ], "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VQB6", "url": "https://www.uniprot.org/uniprotkb/Q9VQB6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Atxn7", "url": "https://www.uniprot.org/uniprotkb/Q9VQB6", "locus": { "chromosome": "2L", "start_pos": 2380506, "end_pos": 2375841, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0031420", "url": "https://www.ensemblgenomes.org/id/FBgn0031420" } ] } } ], "crossref": [ { "id": "FB:FBgn0031420", "url": "https://alliancegenome.org/gene/FB:FBgn0031420", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "Q9VQB6", "url": "https://alphafold.ebi.ac.uk/entry/Q9VQB6", "database": "AlphaFoldDB", "categories": [] }, { "id": "FBgn0031420", "url": "https://bgee.org/?page=gene&gene_id=FBgn0031420", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0031420", "url": "https://flybase.org/reports/FBgn0031420", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "33423", "url": "https://www.ncbi.nlm.nih.gov/gene/33423", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VQB6", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VQB6*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR053109", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053109", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG9866", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG9866", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AADMAYY", "url": "https://omabrowser.org/oma/group/AADMAYY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VQB6", "url": "https://www.orthodb.org/?gene=Q9VQB6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31534", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31534", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31534:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31534:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PR:Q9VQB6", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q9VQB6", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001259932", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259932", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VQB6", "url": "https://www.uniprot.org/uniprotkb/Q9VQB6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VQB6-1", "url": "https://www.uniprot.org/uniprotkb/Q9VQB6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPLNDVAPAGGGAYPENGTKHKVSGMWKPDSSAGSNSGSGSAGLSLFSLQGQKWQQVFDMEKVIKQLRTAEKTYLRGGKNSSAGADQQAKVQVQRLQSADMAYYDLAPKLASRDIVLCSSCSGCYTKAGFQHHIALQHPSVWEATSSKVNPNPNGTAISSDSRLTATEISQEGGAIVPSSPTDTLSASTLSSCSNGSSSSASLQHPAAAGSSSTTSSSSSSRHKSSSSKSSSSSSSKGSSSTSAGSRSRSKSSKNRHHSSPAPALLESNHKESKGSKKSSAIAAPPVVAAVVKEEPPSVGAAPAAITMFSSSSNSSCSLPPTPTLGAASSEVAMGVNYSPAQLQTDAEKLPELQPKKKLKGSSDHRIKAEKEKNKDKSLVNSYEQQQVLSELDQAVSSITGAVSAEQVAPDEEELPLPNTSDENSISQTLDEMLDSKLINEILNNFDESALDTSQQQSQQQAQNGSLSHPAQATKRLRFEDGTIGEDYAVYQQQAVQQVYGEEEHQQELTTIDAMQLQQLIYQQQQMLEQQQLQEQQQQQQQDQKLQDHEQQRQFSVYNVPSLTDEAMVNPQQQQLEEHMILPSIIYEITESNPVSMLEQKVLAEFLTNAGYENVDVNVVQSGGIQTNLSSGTEANQLADELADFEFSKLETVSDTVKTVKLEAKAASQPPTTNPQINHHPSLANAKYHEDSYFNVMLYSGAPRPLAMNTFGMVKLPQGLGVTFRKNLLTTRKANNNLLSLSGGNHLGVVGQLARTPPPPSPALSNGLPGKNPASGRTIYAQRSNVIAQDRLRCNKRALVGGKAGGGSSGSPGVMTAKRLNELLMGKAKKEEKPPPDSEDGGEQPTKDKERDKEEDNKLTFSFYEKRRRLLAGKLEQLQPLGRPSFTLPLQSNHNASQSQSHSPQQLLKKQLLRTLSDSSSNMNISNMNNISNLNSSNTPSANSNPPWKGNSSNPGGNSTPTSSDLMRVFV", "length": 971, "header": "sp|Q9VQB6-1|ATX7_DROME Isoform 1 of Ataxin-7 OS=Drosophila melanogaster OX=7227 GN=Atxn7 PE=1 SV=1 CANONICAL=Q9VQB6-1" }, "isoforms": [ { "isoform_ac": "Q9VQB6-1", "url": "https://www.uniprot.org/uniprotkb/Q9VQB6/entry#Q9VQB6-1", "sequence": { "sequence": "MPLNDVAPAGGGAYPENGTKHKVSGMWKPDSSAGSNSGSGSAGLSLFSLQGQKWQQVFDMEKVIKQLRTAEKTYLRGGKNSSAGADQQAKVQVQRLQSADMAYYDLAPKLASRDIVLCSSCSGCYTKAGFQHHIALQHPSVWEATSSKVNPNPNGTAISSDSRLTATEISQEGGAIVPSSPTDTLSASTLSSCSNGSSSSASLQHPAAAGSSSTTSSSSSSRHKSSSSKSSSSSSSKGSSSTSAGSRSRSKSSKNRHHSSPAPALLESNHKESKGSKKSSAIAAPPVVAAVVKEEPPSVGAAPAAITMFSSSSNSSCSLPPTPTLGAASSEVAMGVNYSPAQLQTDAEKLPELQPKKKLKGSSDHRIKAEKEKNKDKSLVNSYEQQQVLSELDQAVSSITGAVSAEQVAPDEEELPLPNTSDENSISQTLDEMLDSKLINEILNNFDESALDTSQQQSQQQAQNGSLSHPAQATKRLRFEDGTIGEDYAVYQQQAVQQVYGEEEHQQELTTIDAMQLQQLIYQQQQMLEQQQLQEQQQQQQQDQKLQDHEQQRQFSVYNVPSLTDEAMVNPQQQQLEEHMILPSIIYEITESNPVSMLEQKVLAEFLTNAGYENVDVNVVQSGGIQTNLSSGTEANQLADELADFEFSKLETVSDTVKTVKLEAKAASQPPTTNPQINHHPSLANAKYHEDSYFNVMLYSGAPRPLAMNTFGMVKLPQGLGVTFRKNLLTTRKANNNLLSLSGGNHLGVVGQLARTPPPPSPALSNGLPGKNPASGRTIYAQRSNVIAQDRLRCNKRALVGGKAGGGSSGSPGVMTAKRLNELLMGKAKKEEKPPPDSEDGGEQPTKDKERDKEEDNKLTFSFYEKRRRLLAGKLEQLQPLGRPSFTLPLQSNHNASQSQSHSPQQLLKKQLLRTLSDSSSNMNISNMNNISNLNSSNTPSANSNPPWKGNSSNPGGNSTPTSSDLMRVFV", "length": 971, "header": "sp|Q9VQB6-1|ATX7_DROME Isoform 1 of Ataxin-7 OS=Drosophila melanogaster OX=7227 GN=Atxn7 PE=1 SV=1 CANONICAL=Q9VQB6-1" }, "locus": { "chromosome": "2L", "start_pos": 2375841, "end_pos": 2380506, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0077765", "url": "https://www.ensemblgenomes.org/id/FBtr0077765" }, { "database": "Ensembl Peptide", "id": "FBpp0077445", "url": "https://www.ensemblgenomes.org/id/FBpp0077445" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VQB6", "url": "https://www.uniprot.org/uniprotkb/Q9VQB6" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "A Drosophila full-length cDNA resource.", "journal": "Genome Biol.", "date": "2002", "authors": "Stapleton M, Carlson J, Brokstein P, Yu C, Champe M, George R, Guarin H, Kronmiller B, Pacleb J, Park S, Wan K, Rubin GM, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQB6", "url": "https://www.uniprot.org/uniprotkb/Q9VQB6" } ], "reference": [ { "type": "PubMed", "id": "12537569", "url": "https://glygen.org/publication/PubMed/12537569" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQB6", "url": "https://www.uniprot.org/uniprotkb/Q9VQB6" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "A novel histone fold domain-containing protein that replaces TAF6 in Drosophila SAGA is required for SAGA-dependent gene expression.", "journal": "Genes & development", "date": "2009-12-15", "authors": "Weake Vikki M, Swanson Selene K, Mushegian Arcady, Florens Laurence, Washburn Michael P, Abmayr Susan M, Workman Jerry L", "evidence": [ { "database": "UniProtKB", "id": "Q9VQB6", "url": "https://www.uniprot.org/uniprotkb/Q9VQB6" } ], "reference": [ { "type": "PubMed", "id": "20008933", "url": "https://glygen.org/publication/PubMed/20008933" } ] }, { "title": "Post-transcription initiation function of the ubiquitous SAGA complex in tissue-specific gene activation.", "journal": "Genes & development", "date": "2011-07-15", "authors": "Weake Vikki M, Dyer Jamie O, Seidel Christopher, Box Andrew, Swanson Selene K, Peak Allison, Florens Laurence, Washburn Michael P, Abmayr Susan M, Workman Jerry L", "evidence": [ { "database": "UniProtKB", "id": "Q9VQB6", "url": "https://www.uniprot.org/uniprotkb/Q9VQB6" } ], "reference": [ { "type": "PubMed", "id": "21764853", "url": "https://glygen.org/publication/PubMed/21764853" } ] }, { "title": "Loss of Drosophila Ataxin-7, a SAGA subunit, reduces H2B ubiquitination and leads to neural and retinal degeneration.", "journal": "Genes & development", "date": "2014-02-01", "authors": "Mohan Ryan D, Dialynas George, Weake Vikki M, Liu Jianqi, Martin-Brown Skylar, Florens Laurence, Washburn Michael P, Workman Jerry L, Abmayr Susan M", "evidence": [ { "database": "UniProtKB", "id": "Q9VQB6", "url": "https://www.uniprot.org/uniprotkb/Q9VQB6" } ], "reference": [ { "type": "PubMed", "id": "24493646", "url": "https://glygen.org/publication/PubMed/24493646" } ] }, { "title": "Enzymatic modules of the SAGA chromatin-modifying complex play distinct roles in Drosophila gene expression and development.", "journal": "Genes & development", "date": "2017-08-01", "authors": "Li Xuanying, Seidel Christopher W, Szerszen Leanne T, Lange Jeffrey J, Workman Jerry L, Abmayr Susan M", "evidence": [ { "database": "UniProtKB", "id": "Q9VQB6", "url": "https://www.uniprot.org/uniprotkb/Q9VQB6" } ], "reference": [ { "type": "PubMed", "id": "28887412", "url": "https://glygen.org/publication/PubMed/28887412" } ] }, { "title": "The Drosophila Dbf4 ortholog Chiffon forms a complex with Gcn5 that is necessary for histone acetylation and viability.", "journal": "Journal of cell science", "date": "2019-01-16", "authors": "Torres-Zelada Eliana F, Stephenson Robert E, Alpsoy Aktan, Anderson Benjamin D, Swanson Selene K, Florens Laurence, Dykhuizen Emily C, Washburn Michael P, Weake Vikki M", "evidence": [ { "database": "UniProtKB", "id": "Q9VQB6", "url": "https://www.uniprot.org/uniprotkb/Q9VQB6" } ], "reference": [ { "type": "PubMed", "id": "30559249", "url": "https://glygen.org/publication/PubMed/30559249" } ] }, { "title": "Ataxin-7 and Non-stop coordinate SCAR protein levels, subcellular localization, and actin cytoskeleton organization.", "journal": "eLife", "date": "2019-07-26", "authors": "Cloud Veronica, Thapa Ada, Morales-Sosa Pedro, Miller Tayla M, Miller Sara A, Holsapple Daniel, Gerhart Paige M, Momtahan Elaheh, Jack Jarrid L, Leiva Edgardo, Rapp Sarah R, Shelton Lauren G, Pierce Richard A, Martin-Brown Skylar, Florens Laurence, Washburn Michael P, Mohan Ryan D", "evidence": [ { "database": "UniProtKB", "id": "Q9VQB6", "url": "https://www.uniprot.org/uniprotkb/Q9VQB6" } ], "reference": [ { "type": "PubMed", "id": "31348003", "url": "https://glygen.org/publication/PubMed/31348003" } ] } ], "pathway": [ { "id": "dme:Dmel_CG9866", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG9866", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 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"description": "" }, { "id": "MONDO:0011303", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011303", "name": "FSGS1", "description": "" }, { "id": "MONDO:0011303", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011303", "name": "familial idiopathic steroid-resistant nephrotic syndrome with focal segmental glomerulosclerosis", "description": "" }, { "id": "MONDO:0011303", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011303", "name": "focal segmental glomerulosclerosis 1", "description": "" }, { "id": "MONDO:0011303", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011303", "name": "focal segmental glomerulosclerosis caused by mutation in ACTN4", "description": "" }, { "id": "MONDO:0011303", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011303", "name": "focal segmental glomerulosclerosis type 1", "description": "" }, { "id": "MIM:603278", "resource": "MIM", "url": "https://www.omim.org/entry/603278", "name": "Focal segmental glomerulosclerosis 1", "description": "Focal segmental glomerulosclerosis 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "1312", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1312" } ] }, { "disease_id": "DOID:13809", "recommended_name": { "id": "DOID:13809", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13809", "name": "familial combined hyperlipidemia", "description": "" }, "synonyms": [ { "id": "DOID:13809", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13809", "name": "familial multiple lipoprotein-type hyperlipidemia", "description": "" }, { "id": "DOID:13809", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13809", "name": "mixed hyperlipidaemia", "description": "" }, { "id": "DOID:13809", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13809", "name": "type IIb hyperlipoproteinemia", "description": "" }, { "id": "DOID:13809", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13809", "name": "hyperbetalipoproteinemia with prebetalipoproteinemia", "description": "" }, { "id": "MONDO:0007759", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007759", "name": "hyperlipidemia, familial combined, LPL related", "description": "" }, { "id": "MONDO:0007759", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007759", "name": "combined hyperlipidemia, familial", "description": "" }, { "id": "MONDO:0007759", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007759", "name": "FCHL", "description": "" }, { "id": "MONDO:0007759", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007759", "name": "hyperlipidemia, familial combined", "description": "" }, { "id": "MIM:144250", "resource": "MIM", "url": "https://www.omim.org/entry/144250", "name": "Hyperlipidemia, familial combined, 3", "description": "Hyperlipidemia, familial combined, 3" } ], "unlinked_id_list": [], "evidence": [ { "id": "13809", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13809" } ] }, { "disease_id": "DOID:14118", "recommended_name": { "id": "DOID:14118", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14118", "name": "familial lipoprotein lipase deficiency", "description": "A familial hyperlipemia characterized by a deficiency of the enzyme lipoprotein lipase and the subsequent build up of chylomicrons and increased plasma concentration of triglycerides." }, "synonyms": [ { "id": "DOID:14118", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14118", "name": "Fredrickson type I hyperlipoproteinemia", "description": "" }, { "id": "DOID:14118", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14118", "name": "Fredrickson type I lipaemia", "description": "" }, { "id": "DOID:14118", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14118", "name": "familial LPL deficiency", "description": "" }, { "id": "DOID:14118", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14118", "name": "familial hyperlipoproteinemia type I", "description": "" }, { "id": "DOID:14118", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14118", "name": "hypercholesterinaemic xanthomatosis", "description": "" }, { "id": "DOID:14118", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14118", "name": "hyperchylomicronemia", "description": "" }, { "id": "DOID:14118", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14118", "name": "mixed hyperglyceridemia", "description": "" }, { "id": "MONDO:0009387", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009387", "name": "familial lipoprotein lipase deficiency", "description": "Familial lipoprotein lipase deficiency is a rare genetic disorder is which a person lacks the enzyme lipoprotein lipase, a protein needed to break down fat molecules. Deficiency of this enzyme prevents affected individuals from properly digesting certain fats. This results in the accumulation of fatty droplets called chylomicrons in the blood and an increase in the blood concentration of triglycerides. Symptoms include episodes of abdominal pain, recurrent inflammation of the pancreas (pancreatitis), abnormal enlargement of the liver and/or spleen (hepatosplenomegaly), and the development of skin lesions known as erruptive xanthomas. Familial lipoprotein lipase deficiency is caused by changes (mutations) in the LPL gene. It is inherited in an autosomal recessive pattern. Treatment aims to control symptoms and blood triglyceride levels with a very low-fat diet. Treatment for individual symptoms (i.e. pancreatitis) involves following established treatment guidelines." }, { "id": "MONDO:0009387", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009387", "name": "familial chylomicronemia syndrome", "description": "" }, { "id": "MONDO:0009387", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009387", "name": "hyperlipoproteinemia type I", "description": "" }, { "id": "MONDO:0009387", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009387", "name": "hyperlipoproteinemia, type 1", "description": "" }, { "id": "MONDO:0009387", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009387", "name": "hyperlipoproteinemia, type I", "description": "" }, { "id": "MONDO:0009387", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009387", "name": "type I hyperlipoproteinemia", "description": "" }, { "id": "MONDO:0009387", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009387", "name": "LPL deficiency", "description": "" }, { "id": "MONDO:0009387", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009387", "name": "familial lipoprotein lipase deficiency (disorder) [ambiguous]", "description": "" }, { "id": "MONDO:0009387", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009387", "name": "familial lipoprotein lipase deficiency with type I phenotype", "description": "" }, { "id": "MONDO:0009387", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009387", "name": "high density lipoprotein cholesterol level QTL 11", "description": "" }, { "id": "MONDO:0009387", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009387", "name": "hyperchylomicronemia", "description": "" }, { "id": "MONDO:0009387", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009387", "name": "Burger-Grutz syndrome", "description": "" }, { "id": "MONDO:0009387", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009387", "name": "endogenous hypertriglyceridaemia", "description": "" }, { "id": "MONDO:0009387", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009387", "name": "familial fat-induced hypertriglyceridemia", "description": "" }, { "id": "MONDO:0009387", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009387", "name": "familial hyperchylomicronemia", "description": "" }, { "id": "MONDO:0009387", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009387", "name": "lipoprotein lipase deficiency, familial", "description": "" }, { "id": "MIM:238600", "resource": "MIM", "url": "https://www.omim.org/entry/238600", "name": "Hyperlipoproteinemia 1", "description": "Hyperlipoproteinemia 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "14118", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14118" } ] }, { "disease_id": "DOID:14221", "recommended_name": { "id": "DOID:14221", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14221", "name": "abdominal obesity-metabolic syndrome 1", "description": "An abdominal obesity-metabolic syndrome characterized by insulin resistance and hyperinsulinemia, dyslipidemia, essential hypertension, abdominal obesity, glucose intolerance or noninsulin-dependent diabetes mellitus and an increased risk of cardiovascular events." }, "synonyms": [ { "id": "DOID:14221", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14221", "name": "dysmetabolic syndrome X", "description": "" }, { "id": "DOID:14221", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14221", "name": "metabolic syndrome X", "description": "" }, { "id": "MONDO:0011565", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011565", "name": "metabolic syndrome X", "description": "" }, { "id": "MONDO:0011565", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011565", "name": "abdominal obesity-metabolic syndrome 1", "description": "" }, { "id": "MONDO:0011565", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011565", "name": "metabolic syndrome type X", "description": "" }, { "id": "MONDO:0011565", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011565", "name": "AOMS1", "description": "" }, { "id": "MONDO:0011565", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011565", "name": "abdominal obesity metabolic syndrome", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "14221", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14221" } ] }, { "disease_id": "DOID:2018", "recommended_name": { "id": "DOID:2018", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2018", "name": "hyperinsulinism", "description": "" }, "synonyms": [ { "id": "DOID:2018", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2018", "name": "hyperinsulinemia", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "2018", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2018" } ] }, { "disease_id": "DOID:3393", "recommended_name": { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "coronary artery disease", "description": "An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles." }, "synonyms": [ { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "CHD", "description": "" }, { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "Coronary disease", "description": "" }, { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "coronary arteriosclerosis", "description": "" }, { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "coronary heart disease", "description": "" }, { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "Ischemic Heart Disease", "description": "" }, { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "myocardial ischemia", "description": "" }, { "id": "MONDO:0010331", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010331", "name": "coronary heart disease, susceptibility to, 3", "description": "" }, { "id": "MONDO:0010331", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010331", "name": "coronary heart disease, susceptibility to, 3", "description": "" }, { "id": "MONDO:0010331", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010331", "name": "coronary heart disease, susceptibility to, type 3", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary heart disease, susceptibility to, 1", "description": "Any coronary artery disease in which the cause of the disease is a mutation in the CX3CR1 gene." }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "CX3CR1 coronary artery disease", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary artery disease caused by mutation in CX3CR1", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary artery disease, resistance to", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary heart disease, susceptibility to", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary heart disease, susceptibility to, 1", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary heart disease, susceptibility to, type 1", "description": "" }, { "id": "MONDO:0012009", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012009", "name": "coronary heart disease, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012009", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012009", "name": "coronary heart disease, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012009", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012009", "name": "coronary heart disease, susceptibility to, type 2", "description": "" }, { "id": "MONDO:0012010", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012010", "name": "coronary heart disease, susceptibility to, 4", "description": "" }, { "id": "MONDO:0012010", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012010", "name": "coronary heart disease, susceptibility to, 4", "description": "" }, { "id": "MONDO:0012010", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012010", "name": "coronary heart disease, susceptibility to, type 4", "description": "" }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "coronary artery disease, autosomal dominant, 1", "description": "Any coronary artery disease in which the cause of the disease is a mutation in the MEF2A gene." }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "MEF2A coronary artery disease", "description": "" }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "coronary artery disease caused by mutation in MEF2A", "description": "" }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "coronary artery disease, autosomal dominant, 1", "description": "" }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "coronary artery disease, autosomal dominant, type 1", "description": "" }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "ADCAD1", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "coronary artery disease, autosomal dominant 2", "description": "Any coronary artery disease in which the cause of the disease is a mutation in the LRP6 gene." }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "LRP6 coronary artery disease", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "coronary artery disease caused by mutation in LRP6", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "coronary artery disease, autosomal dominant 2", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "coronary artery disease, autosomal dominant type 2", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "coronary artery disease, autosomal dominant, 2", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "ADCAD2", "description": "" }, { "id": "MONDO:0012628", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012628", "name": "coronary heart disease, susceptibility to, 8", "description": "" }, { "id": "MONDO:0012628", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012628", "name": "CHDS8", "description": "" }, { "id": "MONDO:0012628", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012628", "name": "coronary heart disease, susceptibility to, 8", "description": "" }, { "id": "MONDO:0012788", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012788", "name": "coronary heart disease, susceptibility to, 9", "description": "" }, { "id": "MONDO:0012788", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012788", "name": "CHDS9", "description": "" }, { "id": "MONDO:0012788", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012788", "name": "coronary heart disease, susceptibility to, 9", "description": "" }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "hydatidiform mole, recurrent, 2", "description": "Any complete hydatidiform mole in which the cause of the disease is a mutation in the KHDC3L gene." }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "KHDC3L complete hydatidiform mole", "description": "" }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "complete hydatidiform mole caused by mutation in KHDC3L", "description": "" }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "hydatidiform Mole, recurrent, type 2", "description": "" }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "hydatidiform mole, recurrent, 2", "description": "" }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "HYDM2", "description": "" }, { "id": "MIM:608320", "resource": "MIM", "url": "https://www.omim.org/entry/608320", "name": "Coronary artery disease, autosomal dominant, 1", "description": "Coronary artery disease, autosomal dominant, 1" }, { "id": "MIM:610947", "resource": "MIM", "url": "https://www.omim.org/entry/610947", "name": "Coronary artery disease, autosomal dominant, 2", "description": "Coronary artery disease, autosomal dominant, 2" }, { "id": "MIM:614293", "resource": "MIM", "url": "https://www.omim.org/entry/614293", "name": "Hydatidiform mole, recurrent, 2", "description": "Hydatidiform mole, recurrent, 2" } ], "unlinked_id_list": [ "DOID:11840" ], "evidence": [ { "id": "3393", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3393" } ] }, { "disease_id": "DOID:341", "recommended_name": { "id": "DOID:341", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:341", "name": "peripheral vascular disease", "description": "A vascular disease that is characterized by obstruction of vessels not within the coronary, aortic arch vasculature, or brain." }, "synonyms": [ { "id": "DOID:341", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:341", "name": "arterial occlusive disease", "description": "" } ], "unlinked_id_list": [ "DOID:1729" ], "evidence": [ { "id": "341", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:341" } ] }, { "disease_id": "DOID:3526", "recommended_name": { "id": "DOID:3526", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3526", "name": "cerebral infarction", "description": "A cerebrovascular disease that is characterized by an area of necrotic tissue in the brain resulting from a blockage or narrowing in the arteries supplying blood and oxygen to the brain." }, "synonyms": [ { "id": "DOID:3526", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3526", "name": "Cerebral infarct", "description": "" }, { "id": "MONDO:0020671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0020671", "name": "obsolete susceptibility to ischemic stroke", "description": "" }, { "id": "MONDO:0020671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0020671", "name": "cerebral infarction, susceptibility to", "description": "" }, { "id": "MONDO:0020671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0020671", "name": "ischemic stroke, susceptibility to", "description": "" }, { "id": "MONDO:0020671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0020671", "name": "stroke, ischemic, susceptibility to", "description": "" }, { "id": "MONDO:0020671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0020671", "name": "stroke, susceptibility to", "description": "" }, { "id": "MIM:601367", "resource": "MIM", "url": "https://www.omim.org/entry/601367", "name": "Ischemic stroke", "description": "Ischemic stroke" } ], "unlinked_id_list": [], "evidence": [ { "id": "3526", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3526" } ] }, { "disease_id": "DOID:557", "recommended_name": { "id": "DOID:557", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:557", "name": "kidney disease", "description": "A urinary system disease that is located_in the kidney." }, "synonyms": [ { "id": "DOID:557", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:557", "name": "nephropathy", "description": "" }, { "id": "DOID:557", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:557", "name": "impaired renal function disease", "description": "" } ], "unlinked_id_list": [ "DOID:0081055", "DOID:3116", "DOID:13138", "DOID:3675", "DOID:4455", "DOID:0080616", "DOID:2744", "DOID:9808", "DOID:582" ], "evidence": [ { "id": "557", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:557" } ] }, { "disease_id": "DOID:5844", "recommended_name": { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia." }, "synonyms": [ { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "Myocardial infarct", "description": "" }, { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "heart attack", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, type 2", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ] }, { "disease_id": "DOID:783", "recommended_name": { "id": "DOID:783", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:783", "name": "end stage renal disease", "description": "A chronic kidney disease is characterized by non-functioning kidneys, as the final stage in chronic kidney disease." }, "synonyms": [ { "id": "DOID:783", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:783", "name": "end stage renal failure", "description": "" }, { "id": "DOID:783", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:783", "name": "end-stage kidney disease", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "783", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:783" } ] }, { "disease_id": "DOID:9352", "recommended_name": { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin." }, "synonyms": [ { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "NIDDM", "description": "" }, { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "non-insulin-dependent diabetes mellitus", "description": "" }, { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "type 2 diabetes", "description": "" }, { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "type II diabetes mellitus", "description": "" }, { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "insulin resistance", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type 2 diabetes mellitus", "description": "A type of diabetes mellitus that is characterized by insulin resistance or desensitization and increased blood glucose levels. 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"https://monarchinitiative.org/disease/MONDO:0005148", "name": "adult-onset diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitis type 2", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitis type II", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent, association with", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent, late onset", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, type 2", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, type II", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes, type 2", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "insulin resistance, severe, digenic", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "non-insulin dependent diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "non-insulin dependent diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "noninsulin dependent diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "noninsulin-dependent diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type 2 diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type 2 diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type 2 diabetes mellitus non-insulin dependent", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type II diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type II diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent, 2", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "diabetes mellitus, noninsulin-dependent, 1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "diabetes mellitus, noninsulin-dependent 1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "diabetes mellitus, noninsulin-dependent, 1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "diabetes mellitus, noninsulin-dependent, type 1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "NIDDM1", "description": "" }, { "id": "MONDO:0011072", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011072", "name": "diabetes mellitus, noninsulin-dependent, 2", "description": "" }, { "id": "MONDO:0011072", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011072", "name": "NIDDM2", "description": "" }, { "id": "MONDO:0011072", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011072", "name": "diabetes mellitus, noninsulin-dependent, 2", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "diabetes mellitus, 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"https://monarchinitiative.org/disease/MONDO:0011955", "name": "diabetes mellitus, noninsulin-dependent, 4", "description": "" }, { "id": "MONDO:0011955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011955", "name": "diabetes mellitus, noninsulin-dependent, type 4", "description": "" }, { "id": "MIM:125853", "resource": "MIM", "url": "https://www.omim.org/entry/125853", "name": "Type 2 diabetes mellitus", "description": "Type 2 diabetes mellitus" }, { "id": "MIM:601283", "resource": "MIM", "url": "https://www.omim.org/entry/601283", "name": "Type 2 diabetes mellitus 1", "description": "Type 2 diabetes mellitus 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ] }, { "disease_id": "DOID:9744", "recommended_name": { "id": "DOID:9744", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9744", "name": "type 1 diabetes mellitus", "description": "A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production." }, "synonyms": [ { "id": "DOID:9744", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9744", "name": "IDDM", "description": "" }, { "id": "DOID:9744", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9744", "name": "insulin-dependent diabetes mellitus", "description": "" }, { "id": "DOID:9744", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9744", "name": "type I diabetes mellitus", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "type 1 diabetes mellitus", "description": "A chronic condition characterized by minimal or absent production of insulin by the pancreas." }, { "id": "MONDO:0005147", "resource": "MONDO", "url": 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dependent diabetes", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "juvenile diabetes", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "type 1 diabetes", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "type I diabetes", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "type I diabetes mellitus", "description": "" }, { "id": "MIM:222100", "resource": "MIM", "url": "https://www.omim.org/entry/222100", "name": "Type 1 diabetes mellitus", "description": "Type 1 diabetes mellitus" } ], "unlinked_id_list": [], "evidence": [ { "id": "9744", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9744" } ] }, { "disease_id": 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}, { "id": "R-DME-192456", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-192456", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-8963889", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8963889", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-8964058", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8964058", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_608682", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608682", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VQC2", "url": "https://www.uniprot.org/uniprotkb/Q9VQC2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VQC2-1", "url": "https://www.uniprot.org/uniprotkb/Q9VQC2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWLQCARKPIRADFWLQLLCVSFTLFHLEFAAAQNAGVVAAAVAAGQNQTQVYVTDSCLQKPYRCPHPKIQFYLYTRRTQEQPEFIDVLDPNALYYTHFNPRHPTKIIIHGFGGGRTLSPSPDLREAYFSVGEYNIIIVDYADAVKEPCLSQMDWAPRFGSLCISQLVKYLARHPRGVQPDDLHFIGYSVGAHIAGLVANYLKPEEGKLGRITALDPTIFFYAGANNSRDLDSTDAHFVDVLHTGAGILGQWHSSGHADFYVNGGTRQPACVGSATLFQTLACDHTKVTPYFIESITTTRGFYAGPCPNLFSYLIGWCEPKDSEYVLMGEHCSHKARGNYYVTTNAKAPFARGFPGKGRSNGEYQGVRR", "length": 369, "header": "tr|Q9VQC2-1|Q9VQC2_DROME Isoform 1 of Lipase domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG18641 PE=3 SV=3 CANONICAL=Q9VQC2-1" }, "isoforms": [ { "isoform_ac": "Q9VQC2-1", "url": "https://www.uniprot.org/uniprotkb/Q9VQC2/entry#Q9VQC2-1", "sequence": { "sequence": "MWLQCARKPIRADFWLQLLCVSFTLFHLEFAAAQNAGVVAAAVAAGQNQTQVYVTDSCLQKPYRCPHPKIQFYLYTRRTQEQPEFIDVLDPNALYYTHFNPRHPTKIIIHGFGGGRTLSPSPDLREAYFSVGEYNIIIVDYADAVKEPCLSQMDWAPRFGSLCISQLVKYLARHPRGVQPDDLHFIGYSVGAHIAGLVANYLKPEEGKLGRITALDPTIFFYAGANNSRDLDSTDAHFVDVLHTGAGILGQWHSSGHADFYVNGGTRQPACVGSATLFQTLACDHTKVTPYFIESITTTRGFYAGPCPNLFSYLIGWCEPKDSEYVLMGEHCSHKARGNYYVTTNAKAPFARGFPGKGRSNGEYQGVRR", "length": 369, "header": "tr|Q9VQC2-1|Q9VQC2_DROME Isoform 1 of Lipase domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG18641 PE=3 SV=3 CANONICAL=Q9VQC2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VQC2", "url": "https://www.uniprot.org/uniprotkb/Q9VQC2" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VQC2", "url": "https://www.uniprot.org/uniprotkb/Q9VQC2" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQC2", "url": "https://www.uniprot.org/uniprotkb/Q9VQC2" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQC2", "url": "https://www.uniprot.org/uniprotkb/Q9VQC2" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VQC2", "url": "https://www.uniprot.org/uniprotkb/Q9VQC2" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VQC2", "url": "https://www.uniprot.org/uniprotkb/Q9VQC2" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VQC2", "url": "https://www.uniprot.org/uniprotkb/Q9VQC2" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQC2", "url": "https://www.uniprot.org/uniprotkb/Q9VQC2" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQC2", "url": "https://www.uniprot.org/uniprotkb/Q9VQC2" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VQC2", "url": "https://www.uniprot.org/uniprotkb/Q9VQC2" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VQC2", "url": "https://www.uniprot.org/uniprotkb/Q9VQC2" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG18641", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG18641", "resource": "KEGG Pathway" }, { "id": "R-DME-192456", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-192456", "resource": "Reactome", "description": "Digestion of dietary lipid" }, { "id": "R-DME-8963889", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8963889", "resource": "Reactome", "description": "Assembly of active LPL and LIPC lipase complexes" }, { "id": "R-DME-8964058", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8964058", "resource": "Reactome", "description": "HDL remodeling" } ], "orthologs": [ { "uniprot_canonical_ac": "A8DYT7-1", "protein_name": "Lipase domain-containing protein", "gene_name": "CG9966", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSIYSTLILLLTIVSGFCKGENHTRGWLPEFCVVGEQKCPNSRVSFWLYTNQTRDDPIQLDPLNPQKDVFQPRLPLKILIHGFIGNRNLTPNLEVRDVLLQTQPINVISVDYGTLVRWPCYYPWAVNNAPIVSECLAQMINNLISAGISRREDIHLIGFSLGAQVAGMVANYVSQPLARITGLDPAGPGFMMQPSLQQKLDASDADFVDIIHTDPFFFSMLPPMGHADFYPNLDQLNQRGCSYISNWRFYNCNHYRAAVYYGESIISERGFWAQQCGGWFDFFSQRCSHYSNMPNTQMGYFVSEDASGSYFLTTHEVAPFAKGPLVEVEFDVSELRNFTEIELR", "length": 344 }, "evidence": [ { "id": "HGNC:6619", "url": "https://alliancegenome.org/gene/HGNC:6619#orthology", "database": "AGR" }, { "id": "HGNC:6623", "url": "https://alliancegenome.org/gene/HGNC:6623#orthology", "database": "AGR" }, { "id": "HGNC:6677", "url": "https://alliancegenome.org/gene/HGNC:6677#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "M9MRT1-1", "protein_name": "Lipase domain-containing protein", "gene_name": "chr2L_10724193_10724543.0", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDKMLTSLIALLLSLLSLNPITNASKYHREALQFLLRNGNFDLNPLNCHILLWETCPKRFIDYQLFTSNGPRRGTPLNVKNPITLYKGGFSKHRETVFIIHGFNGTAIDIHLQFLRDAYLSRDFNVITVDWRPLTRYPCYLHSLINTRLTAQCTAQIYAFLTHYGAVRERITCVGHSLGAHICGMISNHLTRKQYRIIGLDPARPLIERMKSNKFRLSIDDANVIQVLHTNAGFLGQEDNSGHLNYCVNGGRIQPFCKGNPIRKSRCSHFLSICYLATATFKHNKFMGVPCPNGCLNLSGSKRLPVSGKVNPFEFASLIREYHIGNDAPDDARGCICIDVPYAKHCPFTDA", "length": 351 }, "evidence": [ { "id": "HGNC:6619", "url": "https://alliancegenome.org/gene/HGNC:6619#orthology", "database": "AGR" }, { "id": "HGNC:6623", "url": "https://alliancegenome.org/gene/HGNC:6623#orthology", "database": "AGR" }, { "id": "HGNC:6677", "url": "https://alliancegenome.org/gene/HGNC:6677#orthology", "database": "AGR" }, { "id": "MGI:96820", "url": "https://alliancegenome.org/gene/MGI:96820#orthology", "database": "AGR" }, { "id": "RGD:1310740", "url": "https://alliancegenome.org/gene/RGD:1310740#orthology", "database": "AGR" }, { "id": "RGD:3017", "url": "https://alliancegenome.org/gene/RGD:3017#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "M9NFL7-1", "protein_name": "Lipase domain-containing protein", "gene_name": "cg5665", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRILCGIVILLRLGALGDIAVDEEGRLTRSWWDAVPRLLTDIATIKANILTAAPLELASNIIDAVCSSTLFMDRIPAQITPDIRKMHFQYMTPCQNYSVPLLEASKLWKHSRFSKGRKVVILATGWTNTVNESSAISMISKAFMCRGDVNFVIVDAADYVDTFYAWSALNTDLIGEHIGVGLTHLIELTPLRNIHLIGGFIKESFVSINSGSDFFVGHSLGAHIMGTAGRTFKKLTGKLIPRITGLDPAKPCFRREKILPGLTRGDAKLVDIIHTNIGILAKRGPLGDVDFYPGGAHPIQPGCLTIGCSHTRAVEYFAESAYPHQEKNFMGKKCASWDELRKRDCSAGIVSPMGYRMNPQARGIYYVDVNGWPPYGRNSENTVDPRLKTCYLCRR", "length": 395 }, "evidence": [ { "id": "HGNC:6619", "url": "https://alliancegenome.org/gene/HGNC:6619#orthology", "database": "AGR" }, { "id": "HGNC:6623", "url": "https://alliancegenome.org/gene/HGNC:6623#orthology", "database": "AGR" }, { "id": "HGNC:6677", "url": "https://alliancegenome.org/gene/HGNC:6677#orthology", "database": "AGR" }, { "id": "MGI:96820", "url": "https://alliancegenome.org/gene/MGI:96820#orthology", "database": "AGR" }, { "id": "RGD:1310740", "url": "https://alliancegenome.org/gene/RGD:1310740#orthology", "database": "AGR" }, { "id": "RGD:3017", "url": "https://alliancegenome.org/gene/RGD:3017#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P06858-1", "protein_name": "Lipoprotein lipase", "gene_name": "LPL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESKALLVLTLAVWLQSLTASRGGVAAADQRRDFIDIESKFALRTPEDTAEDTCHLIPGVAESVATCHFNHSSKTFMVIHGWTVTGMYESWVPKLVAALYKREPDSNVIVVDWLSRAQEHYPVSAGYTKLVGQDVARFINWMEEEFNYPLDNVHLLGYSLGAHAAGIAGSLTNKKVNRITGLDPAGPNFEYAEAPSRLSPDDADFVDVLHTFTRGSPGRSIGIQKPVGHVDIYPNGGTFQPGCNIGEAIRVIAERGLGDVDQLVKCSHERSIHLFIDSLLNEENPSKAYRCSSKEAFEKGLCLSCRKNRCNNLGYEINKVRAKRSSKMYLKTRSQMPYKVFHYQVKIHFSGTESETHTNQAFEISLYGTVAESENIPFTLPEVSTNKTYSFLIYTEVDIGELLMLKLKWKSDSYFSWSDWWSSPGFAIQKIRVKAGETQKKVIFCSREKVSHLQKGKAPAVFVKCHDKSLNKKSG", "length": 475 }, "evidence": [ { "id": "HGNC:6677", "url": "https://alliancegenome.org/gene/HGNC:6677#orthology", "database": "AGR" }, { "id": "MGI:96820", "url": "https://alliancegenome.org/gene/MGI:96820#orthology", "database": "AGR" }, { "id": "RGD:3017", "url": "https://alliancegenome.org/gene/RGD:3017#orthology", "database": "AGR" }, { "id": "FB:FBgn0031426", "url": "https://alliancegenome.org/gene/FB:FBgn0031426#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P07867-1", "protein_name": "Hepatic triacylglycerol lipase", "gene_name": "Lipc", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGNHLQISVSLVLCIFIQSSACGQGVGTEPFGRNLGATEERKPLQKPEIRFLLFKDESDRLGCQLRPQHPETLQECGFNSSHPLVMIIHGWSVDGLLETWIWKIVGALKSRQSQPVNVGLVDWISLAYQHYAIAVRNTRVVGQEVAALLLWLEESMKFSRSKVHLIGYSLGAHVSGFAGSSMGGKRKIGRITGLDPAGPMFEGTSPNERLSPDDANFVDAIHTFTREHMGLSVGIKQPIAHYDFYPNGGSFQPGCHFLELYKHIAEHGLNAITQTINCAHERSVHLFIDSLQHSNLQNTGFQCSNMDSFSQGLCLNCKKGRCNSLGYDIRRIGHVKSKTLFLITRAQSPFKVYHYQFKIQFINQMEKPMEPTFTMTLLGTKEEIKKIPITLGEGITSNKTYSLLITLNKDIGELIMLKFKWENSAVWANVWNTVQTIMLWDTEPHYAGLIVKTIWVKAGETQQRMTFCPDNVDDLQLHPTQEKVFVKCDLKSKD", "length": 494 }, "evidence": [ { "id": "HGNC:6619", "url": "https://alliancegenome.org/gene/HGNC:6619#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P11150-1", "protein_name": "Hepatic triacylglycerol lipase", "gene_name": "LIPC", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDTSPLCFSILLVLCIFIQSSALGQSLKPEPFGRRAQAVETNKTLHEMKTRFLLFGETNQGCQIRINHPDTLQECGFNSSLPLVMIIHGWSVDGVLENWIWQMVAALKSQPAQPVNVGLVDWITLAHDHYTIAVRNTRLVGKEVAALLRWLEESVQLSRSHVHLIGYSLGAHVSGFAGSSIGGTHKIGRITGLDAAGPLFEGSAPSNRLSPDDANFVDAIHTFTREHMGLSVGIKQPIGHYDFYPNGGSFQPGCHFLELYRHIAQHGFNAITQTIKCSHERSVHLFIDSLLHAGTQSMAYPCGDMNSFSQGLCLSCKKGRCNTLGYHVRQEPRSKSKRLFLVTRAQSPFKVYHYQFKIQFINQTETPIQTTFTMSLLGTKEKMQKIPITLGKGIASNKTYSFLITLDVDIGELIMIKFKWENSAVWANVWDTVQTIIPWSTGPRHSGLVLKTIRVKAGETQQRMTFCSENTDDLLLRPTQEKIFVKCEIKSKTSKRKIR", "length": 499 }, "evidence": [ { "id": "HGNC:6619", "url": "https://alliancegenome.org/gene/HGNC:6619#orthology", "database": "AGR" }, { "id": "FB:FBgn0031426", "url": "https://alliancegenome.org/gene/FB:FBgn0031426#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P11152-1", "protein_name": "Lipoprotein lipase", "gene_name": "Lpl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESKALLLVVLGVWLQSLTAFRGGVAAADAGRDFSDIESKFALRTPEDTAEDTCHLIPGLADSVSNCHFNHSSKTFVVIHGWTVTGMYESWVPKLVAALYKREPDSNVIVVDWLYRAQQHYPVSAGYTKLVGNDVARFINWMEEEFNYPLDNVHLLGYSLGAHAAGVAGSLTNKKVNRITGLDPAGPNFEYAEAPSRLSPDDADFVDVLHTFTRGSPGRSIGIQKPVGHVDIYPNGGTFQPGCNIGEAIRVIAERGLGDVDQLVKCSHERSIHLFIDSLLNEENPSKAYRCNSKEAFEKGLCLSCRKNRCNNLGYEINKVRAKRSSKMYLKTRSQMPYKVFHYQVKIHFSGTEDGKQHNQAFEISLYGTVAESENIPFTLPEVSTNKTYSFLIYTEVDIGELLMMKLKWISDSYFSWPDWWSSPSFVIERIRVKAGETQKKVIFCAREKVSHLQKGKDSAVFVKCHDKSLKKSG", "length": 474 }, "evidence": [ { "id": "HGNC:6677", "url": "https://alliancegenome.org/gene/HGNC:6677#orthology", "database": "AGR" }, { "id": "MGI:96820", "url": "https://alliancegenome.org/gene/MGI:96820#orthology", "database": "AGR" }, { "id": "RGD:3017", "url": "https://alliancegenome.org/gene/RGD:3017#orthology", "database": "AGR" }, { "id": "FB:FBgn0031426", "url": "https://alliancegenome.org/gene/FB:FBgn0031426#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P27656-1", "protein_name": "Hepatic triacylglycerol lipase", "gene_name": "Lipc", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGNPLQISIFLVFCIFIQSSACGQGVGTEPFGRSLGATEASKPLKKPETRFLLFQDENDRLGCRLRPQHPETLQECGFNSSQPLIMIIHGWSVDGLLENWIWKIVSALKSRQSQPVNVGLVDWISLAYQHYTIAVQNTRIVGQDVAALLLWLEESAKFSRSKVHLIGYSLGAHVSGFAGSSMDGKNKIGRITGLDPAGPMFEGTSPNERLSPDDANFVDAIHTFTREHMGLSVGIKQPIAHYDFYPNGGSFQPGCHFLELYKHIAEHGLNAITQTIKCAHERSVHLFIDSLQHSDLQSIGFQCSDMGSFSQGLCLSCKKGRCNTLGYDIRKDRSGKSKRLFLITRAQSPFKVYHYQFKIQFINQIEKPVEPTFTMSLLGTKEEIKRIPITLGEGITSNKTYSFLITLDKDIGELILLKFKWENSAVWANVWNTVQTIMLWGIEPHHSGLILKTIWVKAGETQQRMTFCPENLDDLQLHPSQEKVFVNCEVKSKRLTESKEQMSQETHAKK", "length": 510 }, "evidence": [ { "id": "HGNC:6619", "url": "https://alliancegenome.org/gene/HGNC:6619#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q06000-1", "protein_name": "Lipoprotein lipase", "gene_name": "Lpl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESKALLLVALGVWLQSLTAFRGGVAAADGGRDFSDIESKFALRTPEDTAEDTCHLIPGLADSVSNCHFNHSSKTFVVIHGWTVTGMYESWVPKLVAALYKREPDSNVIVVDWLYRAQQHYPVSAGYTKLVGNDVARFINWLEEEFNYPLDNVHLLGYSLGAHAAGVAGSLTNKKVNRITGLDPAGPNFEYAEAPSRLSPDDADFVDVLHTFTRGSPGRSIGIQKPVGHVDIYPNGGTFQPGCNIGEAIRVIAEKGLGDVDQLVKCSHERSIHLFIDSLLNEENPSKAYRCNSKEAFEKGLCLSCRKNRCNNVGYEINKVRAKRSSKMYLKTRSQMPYKVFHYQVKIHFSGTENDKQNNQAFEISLYGTVAESENIPFTLPEVATNKTYSFLIYTEVDIGELLMMKLKWKNDSYFRWSDWWSSPSFVIEKIRVKAGETQKKVIFCAREKVSHLQKGKDAAVFVKCHDKSLKKSG", "length": 474 }, "evidence": [ { "id": "HGNC:6677", "url": "https://alliancegenome.org/gene/HGNC:6677#orthology", "database": "AGR" }, { "id": "MGI:96820", "url": "https://alliancegenome.org/gene/MGI:96820#orthology", "database": "AGR" }, { "id": "RGD:3017", "url": "https://alliancegenome.org/gene/RGD:3017#orthology", "database": "AGR" }, { "id": "FB:FBgn0031426", "url": "https://alliancegenome.org/gene/FB:FBgn0031426#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8VBX1-1", "protein_name": "Endothelial lipase", "gene_name": "Lipg", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRDPVFLLGFWSLYCCFPAGSLTTLRPQGSLRDEHHKPTGVPVTITTKPSVTFNIRTSKDPEHEGCNLSLGDSKLLENCGFNMTAKTFFIIHGWTMSGMFESWLHKLVSALQTREKEANVVVVDWLPLAHQLYIDAVSNTRVVGRRVAGMLNWLQEKGEFSLGDVHLIGYSLGAHVAGYAGNFVKGTVGRITGLDPAGPMFEGVDINRRLSPDDADFVDVLHTYTLSFGLSIGIRMPVGHIDIYPNGGDFQPGCGFNDVMGSFAYGTISEMVKCEHERAVHLFVDSLVNQDKPSFAFQCTDPNRFKRGICLSCRKNRCNNIGYNAKKMRKKRNSKMYLKTRAGMPFRVYHYQLKVHMFSYKNSGDIQPDLYITLYGSNADSQNLPLEIVEKIELNATNTFLVYTEEYLGDLFKIRLTWEGVSSSWYNLWNEFRSYLSQPSSPSRELHIRRIRVKSGETQRKVAFCVQDPMKNSISPGQELWFYKCQNDCRVKN", "length": 493 }, "evidence": [ { "id": "HGNC:6623", "url": "https://alliancegenome.org/gene/HGNC:6623#orthology", "database": "AGR" }, { "id": "RGD:1310740", "url": "https://alliancegenome.org/gene/RGD:1310740#orthology", "database": "AGR" }, { "id": "FB:FBgn0031426", "url": "https://alliancegenome.org/gene/FB:FBgn0031426#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9VJH1-1", "protein_name": "Lipase domain-containing protein", "gene_name": "Dmel\\CG13282", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MHWRLVIGLLLLASFNRETIGKRFLNLKPIPIQHEDESSTEGSTNPTPTSTTTPSNRDITIGPCKWAIGRSCPDPDVKYYIYTRHNPMDRQCLHIDESLEKSNLTDSYFNPRYPTKIIIHGYNSDMFLHPLQQMREEYLAKADYNIIYVDWSILSPGPCYISAVHNTKHAGTCTAQLVERLVETGNTDIHVIGFSLGAQVPNYIARNLSSFMLPRITGLDPAMPLFITSGKADKLDPSDASYVDVIHTNALVQGKMERCGHADFYMNGGIMQPGCNGQKINSFACSHQRAPAYFLESIRSPKGFWGWACSGYISYLLGMCPPTNFLLEAGENIRPTTRGMFMIDTNDSSPFALGKWTDLPTLGAKQPQWRVPTQKLKAPPNQGVDPLLHHIDQFGKLAANFNNLQMWPTEQDPYEHWTSFSPEQKENDSDGDSVEEQDPVEFIEPDDRQMISTEARPTQSWWDYRRNLTYGFMEDNIFSVPTVD", "length": 484 }, "evidence": [ { "id": "HGNC:6619", "url": "https://alliancegenome.org/gene/HGNC:6619#orthology", "database": "AGR" }, { "id": "HGNC:6623", "url": "https://alliancegenome.org/gene/HGNC:6623#orthology", "database": "AGR" }, { "id": "HGNC:6677", "url": "https://alliancegenome.org/gene/HGNC:6677#orthology", "database": "AGR" }, { "id": "MGI:96820", "url": "https://alliancegenome.org/gene/MGI:96820#orthology", "database": "AGR" }, { "id": "RGD:1310740", "url": "https://alliancegenome.org/gene/RGD:1310740#orthology", "database": "AGR" }, { "id": "RGD:3017", "url": "https://alliancegenome.org/gene/RGD:3017#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VRW5-1", "protein_name": "Lipase domain-containing protein", "gene_name": "Dmel\\CG10163", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRAQFTMQKSTAQMIIAVCLICQSLAVEDKDKATNPLNIDSVQKHNVKLLSEQLNRGWRAFCDAPVDEGVMSLFQGINPSDARLHVMTITNQSVELPIKSISQIKDFDINPERKTLIYVNAFHTADSYFSVQEHLTLLQNSRRDLNVIVVDFAKDVAQLYYAVRHHLSVNGYFVYKLLRALKDAGIAVQDITLAGHSVGANIAALGAQLFAKENKQLVGQLLAIDPATMCRTTDILVKQSVALRVVVLHGEGDVFGVRVPLGHIDIYPNGIGYFPRRKLQPGCESKICSHMYPFILFMEALIEGVMIPATKCESWAKFRQGDCNFQNTINIGLIYPANAKGLYFCMTQPNPPFTYMEHGLRYKARRPEKSSEKNRIKF", "length": 378 }, "evidence": [ { "id": "HGNC:6619", "url": "https://alliancegenome.org/gene/HGNC:6619#orthology", "database": "AGR" }, { "id": "HGNC:6623", "url": "https://alliancegenome.org/gene/HGNC:6623#orthology", "database": "AGR" }, { "id": "HGNC:6677", "url": "https://alliancegenome.org/gene/HGNC:6677#orthology", "database": "AGR" }, { "id": "MGI:96820", "url": "https://alliancegenome.org/gene/MGI:96820#orthology", "database": "AGR" }, { "id": "RGD:1310740", "url": "https://alliancegenome.org/gene/RGD:1310740#orthology", "database": "AGR" }, { "id": "RGD:3017", "url": "https://alliancegenome.org/gene/RGD:3017#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VU78-1", "protein_name": "Lipase domain-containing protein", "gene_name": "Dmel\\CG10116", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MQTGVQLALFLTLTIAAVYGETGFFLNTRRVQENAQPIEAEVEALVRSSFYAADPTVVTIPRWLGNISSPEIPAVVSARLQQQDSNIISVDLSEANDETEIIDSVASLVIVLHNQFDMPLDRILVVGFAEGAHLAGGVAAKVQQDLGRQLSQITALDPSSGAELDHKLSQADAEFVEVVHTNAGGEGTWERLGHVDYYPNGGQTQPGCTTDSCSHERAFELLAEMWSPENDFVSARCGSVETLSASSCRWSTHKMGQKQEEEQPASGIYFLETRQSSPFSRGAYFISFL", "length": 289 }, "evidence": [ { "id": "HGNC:6619", "url": "https://alliancegenome.org/gene/HGNC:6619#orthology", "database": "AGR" }, { "id": "HGNC:6623", "url": "https://alliancegenome.org/gene/HGNC:6623#orthology", "database": "AGR" }, { "id": "HGNC:6677", "url": "https://alliancegenome.org/gene/HGNC:6677#orthology", "database": "AGR" }, { "id": "MGI:96820", "url": "https://alliancegenome.org/gene/MGI:96820#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VX69-1", "protein_name": "Lipase domain-containing protein", "gene_name": "Dmel\\CG5162", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGRVPAKMHTLLALLLQLLVASIHAIEWSLPDVINSIGNVGTSIVDPSLLPTPQGLLEGSKQLIAGYPFEFVSNSLNVICSQALASNKIKSKYSPDINKMNFQLQTACEKKNFPLTSPESMWKSPLFDVKKKVVILATGWTTTVNGSDTIEVFSKAYNCRGDVNFVAVDAARFVDTLYTWSAFNTEEIGENIALGLVKLLDLVPVENIHLIGHSLGAHIVGSAGRHLQHLTNQTIPRITGLDPAKPCFNEGEALSGLMRGDAHFVDVIHSNPGVLGKRDPVGDVDFYPGGMSPLAAGCFSVTCAHARSWEYFAETVFPGNERNFMATRCNSISKLRDFRCPGDEVPMGYAVPQNIKGNYFLEVSASAPFGMHASVVRSAHLEHCGLCPESTSTTEVPSTTTTGKPGSWFSG", "length": 411 }, "evidence": [ { "id": "HGNC:6619", "url": "https://alliancegenome.org/gene/HGNC:6619#orthology", "database": "AGR" }, { "id": "HGNC:6623", "url": "https://alliancegenome.org/gene/HGNC:6623#orthology", "database": "AGR" }, { "id": "HGNC:6677", "url": "https://alliancegenome.org/gene/HGNC:6677#orthology", "database": "AGR" }, { "id": "MGI:96820", "url": "https://alliancegenome.org/gene/MGI:96820#orthology", "database": "AGR" }, { "id": "RGD:1310740", "url": "https://alliancegenome.org/gene/RGD:1310740#orthology", "database": "AGR" }, { "id": "RGD:3017", "url": "https://alliancegenome.org/gene/RGD:3017#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VX70-1", "protein_name": "Lipase domain-containing protein", "gene_name": "CT41369", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSSSIAVVLVVVLIGISESIKTDSLMMTSSLTPEISKSDKLKLIVSQNAESSKDTDAIETDISNEHDPRDALKDSSSPDADVLRNKTTEGLISLNNKAENTMTGLDDSESLKLARPASSYQEALLNRLQDQLNQFVVGLPLDLGFSTLNYICSTIVDLGVVRSKLIPDMSRMSFLLRSSDDCQNTSIPLTQAEQLWNTTGFYQDRPTVLFITGWTTSINNSNSGPVAKAYLCRNDTNVLILDAANFIDTLYTWSALNTEVIGDYLAKALLRLNTSYVTKQFHLVGHSLGAQIAGSAGRNYRRLSGGQILKRITGLDPANPCFYDGNELEGLRSGDARFVDIIHTNPGMFGTSKRAGDADFFVQGRIPFKPGCESLDPISCSHQRAVDYWTETVYPSNGNDFLAKRCKRYSELLLGNYCKNTNTVMGYAAKATDLGLFYVGANPEEPYGQNANLQSYTNSDTKCGSCAS", "length": 468 }, "evidence": [ { "id": "HGNC:6619", "url": "https://alliancegenome.org/gene/HGNC:6619#orthology", "database": "AGR" }, { "id": "HGNC:6623", "url": "https://alliancegenome.org/gene/HGNC:6623#orthology", "database": "AGR" }, { "id": "HGNC:6677", "url": "https://alliancegenome.org/gene/HGNC:6677#orthology", "database": "AGR" }, { "id": "MGI:96820", "url": "https://alliancegenome.org/gene/MGI:96820#orthology", "database": "AGR" }, { "id": "RGD:1310740", "url": "https://alliancegenome.org/gene/RGD:1310740#orthology", "database": "AGR" }, { "id": "RGD:3017", "url": "https://alliancegenome.org/gene/RGD:3017#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9WVG5-1", "protein_name": "Endothelial lipase", "gene_name": "Lipg", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRNTVFLLGFWSVYCYFPAGSITTLRPQGSLRDEHHKPTGVPATARPSVAFNIRTSKDPEQEGCNLSLGDSKLLENCGFNMTAKTFFIIHGWTMSGMFESWLHKLVSALQMREKDANVVVVDWLPLAHQLYTDAVNNTRVVGQRVAGMLDWLQEKEEFSLGNVHLIGYSLGAHVAGYAGNFVKGTVGRITGLDPAGPMFEGVDINRRLSPDDADFVDVLHTYTLSFGLSIGIRMPVGHIDIYPNGGDFQPGCGFNDVIGSFAYGTISEMVKCEHERAVHLFVDSLVNQDKPSFAFQCTDSSRFKRGICLSCRKNRCNNIGYNAKKMRKKRNSKMYLKTRAGMPFKVYHYQLKVHMFSYNNSGDTQPTLYITLYGSNADSQNLPLEIVEKIELNATNTFLVYTEEDLGDLLKMRLTWEGVAHSWYNLWNEFRNYLSQPSNPSRELYIRRIRVKSGETQRKVTFCTQDPTKSSISPGQELWFHKCQDGWKMKNKTSPFVNLA", "length": 500 }, "evidence": [ { "id": "HGNC:6623", "url": "https://alliancegenome.org/gene/HGNC:6623#orthology", "database": "AGR" }, { "id": "RGD:1310740", "url": "https://alliancegenome.org/gene/RGD:1310740#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y5X9-1", "protein_name": "Endothelial lipase", "gene_name": "LIPG", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSNSVPLLCFWSLCYCFAAGSPVPFGPEGRLEDKLHKPKATQTEVKPSVRFNLRTSKDPEHEGCYLSVGHSQPLEDCSFNMTAKTFFIIHGWTMSGIFENWLHKLVSALHTREKDANVVVVDWLPLAHQLYTDAVNNTRVVGHSIARMLDWLQEKDDFSLGNVHLIGYSLGAHVAGYAGNFVKGTVGRITGLDPAGPMFEGADIHKRLSPDDADFVDVLHTYTRSFGLSIGIQMPVGHIDIYPNGGDFQPGCGLNDVLGSIAYGTITEVVKCEHERAVHLFVDSLVNQDKPSFAFQCTDSNRFKKGICLSCRKNRCNSIGYNAKKMRNKRNSKMYLKTRAGMPFRVYHYQMKIHVFSYKNMGEIEPTFYVTLYGTNADSQTLPLEIVERIEQNATNTFLVYTEEDLGDLLKIQLTWEGASQSWYNLWKEFRSYLSQPRNPGRELNIRRIRVKSGETQRKLTFCTEDPENTSISPGRELWFRKCRDGWRMKNETSPTVELP", "length": 500 }, "evidence": [ { "id": "HGNC:6623", "url": "https://alliancegenome.org/gene/HGNC:6623#orthology", "database": "AGR" }, { "id": "RGD:1310740", "url": "https://alliancegenome.org/gene/RGD:1310740#orthology", "database": "AGR" }, { "id": "FB:FBgn0031426", "url": "https://alliancegenome.org/gene/FB:FBgn0031426#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VQC2", "url": "https://www.uniprot.org/uniprotkb/Q9VQC2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "lipase activity", "id": "GO:0016298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016298", "evidence": [ { "database": "UniProtKB", "id": "Q9VQC2", "url": "https://www.uniprot.org/uniprotkb/Q9VQC2" } ], "pmid": "" }, { "name": "triacylglycerol lipase activity", "id": "GO:0004806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004806", "evidence": [ { "database": "UniProtKB", "id": "Q9VQC2", "url": "https://www.uniprot.org/uniprotkb/Q9VQC2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "Q9VQC2", "url": "https://www.uniprot.org/uniprotkb/Q9VQC2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 226, "end_pos": 228, "annotation": "n_glycosylation_sequon" }, { "start_pos": 48, "end_pos": 50, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VQC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQC2" }, { "id": "PF00151", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00151" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Lipase", "eco_id": "ECO_0000259", "start_pos": 60, "end_pos": 350, "start_aa": "Gln", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 226, "end_pos": 228 }, { "start_pos": 48, "end_pos": 50 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"chemical_mass": 44770.0, "monoisotopic_mass": 44770.0 }, "refseq": { "ac": "NP_608687", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608687" }, "gene_names": [ { "name": "Dmel\\CG3515", "type": "recommended", "evidence": [ { "id": "Q9VQD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQD1" } ] }, { "name": "CG3515", "type": "synonym", "evidence": [ { "id": "NP_608687", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608687" }, { "id": "Q9VQD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQD1" } ] }, { "name": "Dmel\\CG3515", "type": "synonym", "evidence": [ { "id": "NP_608687", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608687" } ] }, { "name": "Dmel_CG3515", "type": "synonym", "evidence": [ { "id": "Q9VQD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQD1" } ] } ], "protein_names": [ { "name": "WD repeat-containing protein 82", "type": "recommended", "evidence": [ { "id": "Q9VQD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQD1/entry#names_and_taxonomy" } ] }, { "name": "CG3515-PA", "type": "synonym", "evidence": [ { "id": "NP_608687", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608687" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_608687", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608687" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VQD1", "url": "https://www.uniprot.org/uniprotkb/Q9VQD1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG3515", "url": "https://www.uniprot.org/uniprotkb/Q9VQD1", "locus": { "chromosome": "2L", "start_pos": 2551145, "end_pos": 2552825, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0031431", "url": "https://www.ensemblgenomes.org/id/FBgn0031431" } ] } } ], "crossref": [ { "id": "FB:FBgn0031431", "url": "https://alliancegenome.org/gene/FB:FBgn0031431", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0031431", "url": "https://bgee.org/?page=gene&gene_id=FBgn0031431", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0031431", "url": "https://flybase.org/reports/FBgn0031431", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "33437", "url": "https://www.ncbi.nlm.nih.gov/gene/33437", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037867", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037867", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG3515", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3515", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WTQLQFA", "url": "https://omabrowser.org/oma/group/WTQLQFA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VQD1", "url": "https://www.orthodb.org/?gene=Q9VQD1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19861", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19861", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19861:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19861:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_608687", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608687", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VQD1", "url": "https://www.uniprot.org/uniprotkb/Q9VQD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VQD1-1", "url": "https://www.uniprot.org/uniprotkb/Q9VQD1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSIRLNDDAMRQFRVAKVFPETKHHTLAMEFSSDGLRLLVCDHSALSIFSSTRQVQVCKVPMHHYLPDVACFVQQDTRVLHSTSKHDYTIRCLDLNTRHCVRVFGGHAKTINRLASQPGGENVFISAGRDDQVYMWDIRVKTHTHRIKNLRRPLCAFDPEGLFLATSSGTEGIQIRDVRMMGGEPSRKFVYQVNAKANWTQLQFAPNGKSLLLSTDHSWCFSVSAIDGTYQQSFTGYSNKLRLPLDATYTPDSQFILSGADKGRIHIWRAADGFPVAVLKGNNMGPVRCMRFNPRATMFVSSDSRIVFWMPMANGVYDWVKRLKPGETISFTDETVQEEAVKAPRTIPMPKPKIETVWKIKRLNRKRACTGDEIVDLTNALHNNDSMEDGEIAED", "length": 395, "header": "tr|Q9VQD1-1|Q9VQD1_DROME Isoform 1 of WD repeat-containing protein 82 OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG3515 PE=3 SV=2 CANONICAL=Q9VQD1-1" }, "isoforms": [ { "isoform_ac": "Q9VQD1-1", "url": "https://www.uniprot.org/uniprotkb/Q9VQD1/entry#Q9VQD1-1", "sequence": { "sequence": "MSIRLNDDAMRQFRVAKVFPETKHHTLAMEFSSDGLRLLVCDHSALSIFSSTRQVQVCKVPMHHYLPDVACFVQQDTRVLHSTSKHDYTIRCLDLNTRHCVRVFGGHAKTINRLASQPGGENVFISAGRDDQVYMWDIRVKTHTHRIKNLRRPLCAFDPEGLFLATSSGTEGIQIRDVRMMGGEPSRKFVYQVNAKANWTQLQFAPNGKSLLLSTDHSWCFSVSAIDGTYQQSFTGYSNKLRLPLDATYTPDSQFILSGADKGRIHIWRAADGFPVAVLKGNNMGPVRCMRFNPRATMFVSSDSRIVFWMPMANGVYDWVKRLKPGETISFTDETVQEEAVKAPRTIPMPKPKIETVWKIKRLNRKRACTGDEIVDLTNALHNNDSMEDGEIAED", "length": 395, "header": "tr|Q9VQD1-1|Q9VQD1_DROME Isoform 1 of WD repeat-containing protein 82 OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG3515 PE=3 SV=2 CANONICAL=Q9VQD1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VQD1", "url": "https://www.uniprot.org/uniprotkb/Q9VQD1" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VQD1", "url": "https://www.uniprot.org/uniprotkb/Q9VQD1" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQD1", "url": "https://www.uniprot.org/uniprotkb/Q9VQD1" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQD1", "url": "https://www.uniprot.org/uniprotkb/Q9VQD1" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VQD1", "url": "https://www.uniprot.org/uniprotkb/Q9VQD1" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VQD1", "url": "https://www.uniprot.org/uniprotkb/Q9VQD1" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VQD1", "url": "https://www.uniprot.org/uniprotkb/Q9VQD1" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQD1", "url": "https://www.uniprot.org/uniprotkb/Q9VQD1" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQD1", "url": "https://www.uniprot.org/uniprotkb/Q9VQD1" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VQD1", "url": "https://www.uniprot.org/uniprotkb/Q9VQD1" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VQD1", "url": "https://www.uniprot.org/uniprotkb/Q9VQD1" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG3515", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3515", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "M0R565-1", "protein_name": "WD repeat-containing protein 82", "gene_name": "Wdr82", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKLTDSVLRSFRVAKVFRENSDKINCFDFSPNGETVISSSDDDSIVLYDCQEGKPKRTLYSKKYGVDLIRYTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRLWDLRSPNCQGLMHLQGKPVCSFDPEGLIFAAGVNSEMVKLYDLRSFDKGPFATFKMQYDRTCEWTGLKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGGYANSKAVTLEASFTPDSQFIMIGSEDGKIHVWNGESGIKVAVLDGKHTGPITCLQFNPKFMTFASACSNMKWWLPCYPVS", "length": 314 }, "evidence": [ { "id": "FB:FBgn0031431", "url": "https://alliancegenome.org/gene/FB:FBgn0031431#orthology", "database": "AGR" }, { "id": "HGNC:28826", "url": "https://alliancegenome.org/gene/HGNC:28826#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-333", "url": 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}, { "name": "Dmel_CG9881", "type": "synonym", "evidence": [ { "id": "Q9VQD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQD8" } ] }, { "name": "P16-ARC", "type": "synonym", "evidence": [ { "id": "NP_001259945", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259945" }, { "id": "Q9VQD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQD8" } ] }, { "name": "p16-ARC", "type": "synonym", "evidence": [ { "id": "NP_001259945", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259945" }, { "id": "Q9VQD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQD8" } ] }, { "name": "p16-arc", "type": "synonym", "evidence": [ { "id": "NP_001259945", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259945" }, { "id": "Q9VQD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQD8" } ] }, { "name": "p16", "type": "synonym", "evidence": [ { 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"12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQD8", "url": "https://www.uniprot.org/uniprotkb/Q9VQD8" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQD8", "url": "https://www.uniprot.org/uniprotkb/Q9VQD8" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VQD8", "url": "https://www.uniprot.org/uniprotkb/Q9VQD8" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VQD8", "url": "https://www.uniprot.org/uniprotkb/Q9VQD8" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VQD8", "url": "https://www.uniprot.org/uniprotkb/Q9VQD8" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQD8", "url": "https://www.uniprot.org/uniprotkb/Q9VQD8" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQD8", "url": "https://www.uniprot.org/uniprotkb/Q9VQD8" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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due to defective mitochondrial and peroxisomal fission 1", "description": "A syndrome that has_material_basis_in heterozygous mutation in the DNM1L gene, and is characterized by delayed psychomotor development and has_symptom hypotonia that may lead to death in childhood." }, "synonyms": [ { "id": "MONDO:0013726", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013726", "name": "encephalopathy, lethal, due to defective mitochondrial peroxisomal fission 1", "description": "" }, { "id": "MONDO:0013726", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013726", "name": "DNM1L-associated encephalopathy due to peroxisomal and mitochondrial fission defect", "description": "" }, { "id": "MONDO:0013726", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013726", "name": "encephalopathy, lethal, due to defective mitochondrial peroxisomal fission 1", "description": "" }, { "id": "MONDO:0013726", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013726", "name": "lethal encephalopathy due to mitochondrial and peroxisomal fission defect", "description": "" }, { "id": "MONDO:0013726", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013726", "name": "EMPF", "description": "" }, { "id": "MONDO:0013726", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013726", "name": "EMPF1", "description": "" }, { "id": "MONDO:0013726", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013726", "name": "encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission", "description": "" }, { "id": "MIM:614388", "resource": "MIM", "url": "https://www.omim.org/entry/614388", "name": "Encephalopathy due to defective mitochondrial and peroxisomal fission 1", "description": "Encephalopathy due to defective mitochondrial and peroxisomal fission 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "0070347", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070347" } ] }, { "disease_id": "DOID:0110197", "recommended_name": { "id": "DOID:0110197", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110197", "name": "Charcot-Marie-Tooth disease dominant intermediate B", "description": "A Charcot-Marie-Tooth disease intermediate type that has_material_basis_in mutation in the gene encoding dynamin-2 (DNM2)." }, "synonyms": [ { "id": "DOID:0110197", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110197", "name": "CMTDI1", "description": "" }, { "id": "DOID:0110197", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110197", "name": "CMTDIB", "description": "" }, { "id": "DOID:0110197", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110197", "name": "DI-CMTB", "description": "" }, { "id": "DOID:0110197", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110197", "name": "Charcot-Marie-Tooth neuropathy dominant intermediate B", "description": "" }, { "id": "MONDO:0011674", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011674", "name": "Charcot-Marie-Tooth disease dominant intermediate B", "description": "Autosomal dominant intermediate Charcot-Marie-Tooth disease type B is a rare hereditary motor and sensory neuropathy characterized by intermediate motor median nerve conduction velocities (usually between 25 and 45 m/s) and signs of both demyelination and axonal degeneration in nerve biopsies. It presents with mild to moderately severe, slowly progressive usual clinical features of Charcot-Marie-Tooth disease (muscle weakness and atrophy of the distal extremities, distal sensory loss, reduced or absent deep tendon reflexes, and feet deformities). Other findings include asymptomatic neutropenia and early-onset cataracts." }, { "id": "MONDO:0011674", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011674", "name": "CMTDI1", "description": "" }, { "id": "MONDO:0011674", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011674", "name": "CMTDIB", "description": "" }, { "id": "MONDO:0011674", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011674", "name": "Charcot-Marie-Tooth disease caused by mutation in DNM2", "description": "" }, { "id": "MONDO:0011674", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011674", "name": "Charcot-Marie-Tooth disease dominant intermediate type B", "description": "" }, { "id": "MONDO:0011674", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011674", "name": "Charcot-Marie-Tooth disease, axonal type 2M", "description": "" }, { "id": "MONDO:0011674", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011674", "name": "Charcot-Marie-Tooth disease, dominant Intermediate type B", "description": "" }, { "id": "MONDO:0011674", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011674", "name": "DI-CMTB", "description": "" }, { "id": "MONDO:0011674", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011674", "name": "DNM2 Charcot-Marie-Tooth disease", "description": "" }, { "id": "MONDO:0011674", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011674", "name": "Charcot-Marie-Tooth disease, dominant intermediate B", "description": "" }, { "id": "MONDO:0011674", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011674", "name": "DNM2-related intermediate Charcot-Marie-Tooth neuropathy", "description": "" }, { "id": "MIM:606482", "resource": "MIM", "url": "https://www.omim.org/entry/606482", "name": "Charcot-Marie-Tooth disease, dominant intermediate B", "description": "Charcot-Marie-Tooth disease, dominant intermediate B" } ], "unlinked_id_list": [], "evidence": [ { "id": "0110197", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110197" } ] }, { "disease_id": "DOID:0111223", "recommended_name": { "id": "DOID:0111223", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111223", "name": "centronuclear myopathy 1", "description": "An autosomal dominant centronuclear myopathy characterized by slowly progressive muscle wasting and weakness involving mainly the limb girdle, trunk, and neck muscles that has_material_basis_in heterozygous mutation in DNM2 on 19p13.2." }, "synonyms": [ { "id": "DOID:0111223", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111223", "name": "CNM1", "description": "" }, { "id": "MONDO:0008048", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008048", "name": "autosomal dominant centronuclear myopathy", "description": "An inherited neuromuscular disorder defined by numerous centrally placed nuclei on muscle biopsy and clinical features of a congenital myopathy." }, { "id": "MONDO:0008048", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008048", "name": "AD-CNM", "description": "" }, { "id": "MONDO:0008048", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008048", "name": "CNM1", "description": "" }, { "id": "MONDO:0008048", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008048", "name": "autosomal dominant centronuclear myopathy", "description": "" }, { "id": "MONDO:0008048", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008048", "name": "autosomal dominant centronuclear myopathy caused by mutation in MYF6", "description": "" }, { "id": "MONDO:0008048", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008048", "name": "centronuclear myopathy 1", "description": "" }, { "id": "MONDO:0008048", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008048", "name": "centronuclear myopathy, autosomal dominant", "description": "" }, { "id": "MONDO:0008048", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008048", "name": "centronuclear myopathy, autosomal, modifier of", "description": "" }, { "id": "MONDO:0008048", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008048", "name": "myopathy, centronuclear, 1", "description": "" }, { "id": "MONDO:0008048", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008048", "name": "myopathy, centronuclear, 3", "description": "" }, { "id": "MONDO:0008048", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008048", "name": "myopathy, centronuclear, autosomal dominant", "description": "" }, { "id": "MONDO:0008048", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008048", "name": "myopathy, centronuclear, type 1", "description": "" }, { "id": "MONDO:0008048", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008048", "name": "myopathy, centronuclear, type 3", "description": "" }, { "id": "MONDO:0008048", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008048", "name": "myotubular myopathy, autosomal dominant", "description": "" }, { "id": "MONDO:0008048", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008048", "name": "CNM3", "description": "" }, { "id": "MONDO:0008048", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008048", "name": "DNM2-related centronuclear myopathy", "description": "" }, { "id": "MONDO:0008048", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008048", "name": "autosomal dominant centronuclear myopathy", "description": "An inherited neuromuscular disorder defined by numerous centrally placed nuclei on muscle biopsy and clinical features of a congenital myopathy." }, { "id": "MONDO:0008048", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008048", "name": "AD-CNM", "description": "" }, { "id": "MONDO:0008048", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008048", "name": "CNM1", "description": "" }, { "id": "MONDO:0008048", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008048", "name": "autosomal dominant centronuclear myopathy", "description": "" }, { "id": "MONDO:0008048", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008048", "name": "autosomal dominant centronuclear myopathy caused by mutation in MYF6", "description": "" }, { "id": "MONDO:0008048", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008048", "name": "centronuclear myopathy 1", "description": "" }, { "id": "MONDO:0008048", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008048", "name": "centronuclear myopathy, autosomal dominant", "description": "" }, { "id": "MONDO:0008048", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008048", "name": "centronuclear myopathy, autosomal, modifier of", "description": "" }, { "id": "MONDO:0008048", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008048", "name": "myopathy, centronuclear, 1", "description": "" }, { "id": "MONDO:0008048", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008048", "name": "myopathy, centronuclear, 3", "description": "" }, { "id": "MONDO:0008048", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008048", "name": "myopathy, centronuclear, autosomal dominant", "description": "" }, { "id": "MONDO:0008048", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008048", "name": "myopathy, centronuclear, type 1", "description": "" }, { "id": "MONDO:0008048", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008048", "name": "myopathy, centronuclear, type 3", "description": "" }, { "id": "MONDO:0008048", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008048", "name": "myotubular myopathy, autosomal dominant", "description": "" }, { "id": "MONDO:0008048", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008048", "name": "CNM3", "description": "" }, { "id": "MONDO:0008048", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008048", "name": "DNM2-related centronuclear myopathy", "description": "" }, { "id": "MIM:160150", "resource": "MIM", "url": "https://www.omim.org/entry/160150", "name": "Myopathy, centronuclear, 1", "description": "Myopathy, centronuclear, 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "0111223", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111223" } ] }, { "disease_id": "DOID:0111438", "recommended_name": { "id": "DOID:0111438", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111438", "name": "optic atrophy 5", "description": "An optic atrophy characterized by degeneration of retinal ganglion cells resulting in slowly progressive visual loss with variable onset from the first to third decades that has_material_basis_in heterozygous of mutation in DNM1L on chromosome 12p11.21." }, "synonyms": [ { "id": "DOID:0111438", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111438", "name": "OPA5", "description": "" }, { "id": "MONDO:0012543", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012543", "name": "optic atrophy 5", "description": "" }, { "id": "MONDO:0012543", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012543", "name": "OPA5", "description": "" }, { "id": "MONDO:0012543", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012543", "name": "optic atrophy 5", "description": "" }, { "id": "MIM:610708", "resource": "MIM", "url": "https://www.omim.org/entry/610708", "name": "Optic atrophy 5", "description": "Optic atrophy 5" } ], "unlinked_id_list": [], "evidence": [ { "id": "0111438", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111438" } ] }, { "disease_id": "DOID:0112202", "recommended_name": { "id": "DOID:0112202", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0112202", "name": "developmental and epileptic encephalopathy", "description": "An electroclinical syndrome characterized by epileptiform activity and at least one other pathology that together contribute to cognitive and behavioral impairments including developmental delay or regression with onset anywhere from birth to adulthood." }, "synonyms": [ { "id": "MONDO:0010632", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010632", "name": "developmental and epileptic encephalopathy, 1", "description": "Any early infantile epileptic encephalopathy in which the cause of the disease is a mutation in the ARX gene." }, { "id": "MONDO:0010632", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010632", "name": "ARX early infantile epileptic encephalopathy", "description": "" }, { "id": "MONDO:0010632", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010632", "name": "DEE1", "description": "" }, { "id": "MONDO:0010632", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010632", "name": "EIEE1", "description": "" }, { "id": "MONDO:0010632", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010632", "name": "developmental and epileptic encephalopathy 1, X-linked recessive", "description": "" }, { "id": "MONDO:0010632", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010632", "name": "early infantile epileptic encephalopathy caused by mutation in ARX", "description": "" }, { "id": "MONDO:0010632", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010632", "name": "early infantile epileptic encephalopathy caused by mutation in arx", "description": "" }, { "id": "MONDO:0010632", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010632", "name": "epileptic encephalopathy, early infantile, 1", "description": "" }, { "id": "MONDO:0010632", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010632", "name": "epileptic encephalopathy, early infantile, type 1", "description": "" }, { "id": "MONDO:0010632", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010632", "name": "XMESID", "description": "" }, { "id": "MIM:308350", "resource": "MIM", "url": "https://www.omim.org/entry/308350", "name": "Developmental and epileptic encephalopathy 1", "description": "Developmental and epileptic encephalopathy 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "0112202", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112202" } ] }, { "disease_id": "DOID:10652", "recommended_name": { "id": "DOID:10652", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid." }, "synonyms": [ { "id": "DOID:10652", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10652", "name": "Alzheimer disease", "description": "" }, { "id": "DOID:10652", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10652", "name": "Alzheimers dementia", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ] }, { "disease_id": "DOID:11252", "recommended_name": { "id": "DOID:11252", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11252", "name": "microcytic anemia", "description": "An anemia that is characterized by a low normal mean corpuscular volume (MCV) (less than 80 fL) and is defined by the presence of small, often hypochromic, red blood cells in a peripheral blood smear." }, "synonyms": [ { "id": "MONDO:0008788", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008788", "name": "IRIDA syndrome", "description": "IRIDA (Iron-refractory iron deficiency anemia) syndrome is a rare autosomal recessive iron metabolism disorder characterized by iron deficiency anemia (hypochromic, microcytic) that is often unresponsive to oral iron intake and partially responsive to parenteral iron treatment." }, { "id": "MONDO:0008788", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008788", "name": "IRIDA syndrome", "description": "" }, { "id": "MONDO:0008788", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008788", "name": "iron-refractory iron deficiency anaemia", "description": "" }, { "id": "MONDO:0008788", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008788", "name": "iron-refractory iron deficiency anemia", "description": "" }, { "id": "MONDO:0008788", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008788", "name": "IRIDA", "description": "" }, { "id": "MONDO:0008788", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008788", "name": "anemia, hypochromic microcytic, with defect in iron metabolism", "description": "" }, { "id": "MONDO:0008788", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008788", "name": "pseudo-iron-deficiency Anaemia", "description": "" }, { "id": "MIM:206200", "resource": "MIM", "url": "https://www.omim.org/entry/206200", "name": "Iron-refractory iron deficiency anemia", "description": "Iron-refractory iron deficiency anemia" } ], "unlinked_id_list": [], "evidence": [ { "id": "11252", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11252" } ] }, { "disease_id": "DOID:12930", "recommended_name": { "id": "DOID:12930", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently." }, "synonyms": [ { "id": "DOID:12930", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12930", "name": "primary dilated cardiomyopathy", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "dilated cardiomyopathy 1A", "description": "Familial dilated cardiomyopathy with conduction defect due to LMNA mutation is a rare familial dilated cardiomyopathy characterized by left ventricular enlargement and/or reduced systolic function preceded or accompanied by significant conduction system disease and/or arrhythmias including bradyarrhythmias, supraventricular or ventricular arrhythmias. Disease onset is usually in early to mid-adulthood. Sudden cardiac death may occur and may be the presenting symptom. In some cases, it is associated with skeletal myopathy and elevated serum creatine kinase." }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "CDCD1", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "LMNA familial isolated dilated cardiomyopathy", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "cardiomyopathy dilated with conduction defect type 1", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "cardiomyopathy, dilated, type 1A", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "dilated cardiomyopathy 1A", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "dilated cardiomyopathy type 1A", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "familial dilated cardiomyopathy with conduction defect due to LMNA mutation", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "familial isolated dilated cardiomyopathy caused by mutation in LMNA", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "cardiomyopathy, dilated, 1A", "description": "" }, { "id": "MIM:115200", "resource": "MIM", "url": "https://www.omim.org/entry/115200", "name": "Cardiomyopathy, dilated, 1A", "description": "Cardiomyopathy, dilated, 1A" } ], "unlinked_id_list": [], "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ] }, { "disease_id": "DOID:13711", "recommended_name": { "id": "DOID:13711", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13711", "name": "dental fluorosis", "description": "A tooth disease characterized by enamel discoloration resulting from excess fluoride ingestion during tooth formation." }, "synonyms": [ { "id": "DOID:13711", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13711", "name": "Intrinsic enamel discolouration of fluorosis", "description": "" }, { "id": "DOID:13711", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13711", "name": "Mottled teeth", "description": "" }, { "id": "DOID:13711", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13711", "name": "Mottling of enamel", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "13711", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13711" } ] }, { "disease_id": "DOID:14330", "recommended_name": { "id": "DOID:14330", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions." }, "synonyms": [ { "id": "DOID:14330", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14330", "name": "Parkinson disease", "description": "" }, { "id": "DOID:14330", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14330", "name": "paralysis agitans", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "late-onset Parkinson disease", "description": "A Parkinson disease that begins after around the age of 50." }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "LOPD", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "PARK", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "PD", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "Parkinson disease, age of onset, modifier, Multifactorial", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "Parkinson disease, late-onset", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "Parkinson disease, late-onset, susceptibility to, Multifactorial", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "Parkinson disease, susceptibility to, Multifactorial", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "autosomal dominant late-onset Parkinson disease", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "hereditary late onset Parkinson disease", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "hereditary late-onset Parkinson disease", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "late-onset Parkinson disease", "description": "" }, { "id": "MIM:168600", "resource": "MIM", "url": "https://www.omim.org/entry/168600", "name": "Parkinson disease", "description": "Parkinson disease" } ], "unlinked_id_list": [], "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ] }, { "disease_id": "DOID:2476", "recommended_name": { "id": "DOID:2476", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2476", "name": "hereditary spastic paraplegia", "description": "A paraplegia that is characterized by progressive stiffness and contraction (spasticity) in the lower limbs." }, "synonyms": [ { "id": "DOID:2476", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2476", "name": "French settlement disease", "description": "" }, { "id": "DOID:2476", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2476", "name": "Strumpell-Lorrain disease", "description": "" }, { "id": "DOID:2476", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2476", "name": "familial spastic paraplegia", "description": "" }, { "id": "DOID:2476", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2476", "name": "hereditary spastic paraparesis", "description": "" }, { "id": "MONDO:0010559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010559", "name": "MASA syndrome", "description": "MASA syndrome (Mental retardation, Aphasia, Spastic paraplegia, Adducted thumbs) is a historical term used to describe a phenotype now considered to be part of the X-linked L1 clinical spectrum (L1 syndrome). MASA is characterized by mild to moderate intellectual deficit, delayed development of speech, hypotonia progressing to spasticity or spastic paraplegia, adducted thumbs, and mild to moderate distension of the cerebral ventricles." }, { "id": "MONDO:0010559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010559", "name": "Gareis-Mason syndrome", "description": "" }, { "id": "MONDO:0010559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010559", "name": "MASA syndrome", "description": "" }, { "id": "MONDO:0010559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010559", "name": "intellectual disability-aphasia-shuffling gait-adducted thumbs syndrome", "description": "" }, { "id": "MONDO:0010559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010559", "name": "masa syndrome, X-linked recessive", "description": "" }, { "id": "MONDO:0010559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010559", "name": "spastic paraplegia, X-linked", "description": "" }, { "id": "MONDO:0010559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010559", "name": "Clasped thumb and mental retardation", "description": "" }, { "id": "MONDO:0010559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010559", "name": "adducted thumb with mental retardation", "description": "" }, { "id": "MONDO:0010559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010559", "name": "intellectual disability aphasia shuffling Gait adducted thumbs (MASA)", "description": "" }, { "id": "MONDO:0010559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010559", "name": "mental retardation aphasia shuffling Gait adducted thumbs (MASA)", "description": "" }, { "id": "MONDO:0010559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010559", "name": "mental retardation, aphasia, shuffling Gait, and adducted thumbs", "description": "" }, { "id": "MONDO:0010559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010559", "name": "spastic paraplegia 1", "description": "" }, { "id": "MONDO:0010559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010559", "name": "thumb congenital clasped with intellectual disability", "description": "" }, { "id": "MONDO:0010559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010559", "name": "thumb congenital clasped with mental retardation", "description": "" }, { "id": "MONDO:0010559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010559", "name": "thumb, congenital Clasped, with mental retardation", "description": "" }, { "id": "MIM:303350", "resource": "MIM", "url": "https://www.omim.org/entry/303350", "name": "MASA syndrome", "description": "MASA syndrome" } ], "unlinked_id_list": [ "DOID:0110771" ], "evidence": [ { "id": "2476", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2476" } ] }, { "disease_id": "DOID:3770", "recommended_name": { "id": "DOID:3770", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3770", "name": "pulmonary fibrosis", "description": "An interstitial lung disease that is characterized by destruction, scarring, and thickening of the interstitial lung tissues and progressive pulmonary function loss in a restrictive pattern, has_symptom progressive shortness of breath, fatigue, and chronic cough, possibly has_material_basis_in exposure to certain chemicals, autoimmune conditions, and radiation. It can be caused by inhaling hazardous chemicals, certain diseases, medication and genetics or unknown causes." }, "synonyms": [ { "id": "DOID:3770", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3770", "name": "Fibrosis of lung", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "3770", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3770" } ] }, { "disease_id": "DOID:784", "recommended_name": { "id": "DOID:784", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:784", "name": "chronic kidney disease", "description": "A kidney failure that is characterized by the gradual loss of kidney function, present for a minimum of 3 months. CKD is classified based on cause, glomerular filtration rate (GFR) category (G2-G5), and albuminuria category (A1-A3)." }, "synonyms": [ { "id": "DOID:784", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:784", "name": "CKD", "description": "" }, { "id": "DOID:784", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:784", "name": "CRF", "description": "" }, { "id": "DOID:784", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:784", "name": "chronic kidney failure", "description": "" }, { "id": "DOID:784", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:784", "name": "chronic renal disease", "description": "" }, { "id": "DOID:784", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:784", "name": "chronic renal failure syndrome", "description": "" }, { "id": "DOID:784", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:784", "name": "renal failure - chronic", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "784", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:784" } ] }, { "disease_id": "DOID:9352", "recommended_name": { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin." }, "synonyms": [ { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "NIDDM", "description": "" }, { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "non-insulin-dependent diabetes mellitus", "description": "" }, { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "type 2 diabetes", "description": "" }, { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "type II diabetes mellitus", "description": "" }, { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "insulin resistance", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type 2 diabetes mellitus", "description": "A type of diabetes mellitus that is characterized by insulin resistance or desensitization and increased blood glucose levels. This is a chronic disease that can develop gradually over the life of a patient and can be linked to both environmental factors and heredity." }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "NIDDM", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "T2D", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "T2DM", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "T2DM - type 2 diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "adult onset diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "adult-onset diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitis type 2", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitis type II", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent, association with", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent, late onset", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, type 2", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, type II", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes, type 2", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "insulin resistance, severe, digenic", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "non-insulin dependent diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "non-insulin dependent diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "noninsulin dependent diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "noninsulin-dependent diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type 2 diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type 2 diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type 2 diabetes mellitus non-insulin dependent", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type II diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type II diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent, 2", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "diabetes mellitus, noninsulin-dependent, 1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "diabetes mellitus, noninsulin-dependent 1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "diabetes mellitus, noninsulin-dependent, 1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "diabetes mellitus, noninsulin-dependent, type 1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "NIDDM1", "description": "" }, { "id": "MONDO:0011072", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011072", "name": "diabetes mellitus, noninsulin-dependent, 2", "description": "" }, { "id": "MONDO:0011072", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011072", "name": "NIDDM2", "description": "" }, { "id": "MONDO:0011072", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011072", "name": "diabetes mellitus, noninsulin-dependent, 2", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "diabetes mellitus, noninsulin-dependent, 3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "diabetes mellitus, noninsulin-dependent, 3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "diabetes mellitus, noninsulin-dependent, type 3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "type 2 diabetes mellitus 3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "NIDDM3", "description": "" }, { "id": "MONDO:0011955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011955", "name": "diabetes mellitus, noninsulin-dependent, 4", "description": "" }, { "id": "MONDO:0011955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011955", "name": "diabetes mellitus, noninsulin-dependent, 4", "description": "" }, { "id": "MONDO:0011955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011955", "name": "diabetes mellitus, noninsulin-dependent, type 4", "description": "" }, { "id": "MIM:125853", "resource": "MIM", "url": "https://www.omim.org/entry/125853", "name": "Type 2 diabetes mellitus", "description": "Type 2 diabetes mellitus" }, { "id": "MIM:601283", "resource": "MIM", "url": "https://www.omim.org/entry/601283", "name": "Type 2 diabetes mellitus 1", "description": "Type 2 diabetes mellitus 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VQE0", "url": "https://www.uniprot.org/uniprotkb/Q9VQE0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Drp1", "url": "https://www.uniprot.org/uniprotkb/Q9VQE0", "locus": { "chromosome": "2L", "start_pos": 2581281, "end_pos": 2585430, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0026479", "url": "https://www.ensemblgenomes.org/id/FBgn0026479" } ] } } ], "crossref": [ { "id": "FB:FBgn0026479", "url": "https://alliancegenome.org/gene/FB:FBgn0026479", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0026479", "url": "https://bgee.org/?page=gene&gene_id=FBgn0026479", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08771", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08771", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0026479", "url": "https://flybase.org/reports/FBgn0026479", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "33445", "url": "https://www.ncbi.nlm.nih.gov/gene/33445", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VQE0", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VQE0*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR000375", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000375", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001401", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001401", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003130", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003130", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019762", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019762", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020850", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020850", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022812", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022812", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030381", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030381", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG3210", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3210", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KICHNCG", "url": "https://omabrowser.org/oma/group/KICHNCG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VQE0", "url": "https://www.orthodb.org/?gene=Q9VQE0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11566", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11566", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11566:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11566:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00350", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00350", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01031", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01031", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02212", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02212", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-75153", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-75153", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001259946", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259946", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q9VQE0", "url": "https://www.uniprot.org/uniprotkb/Q9VQE0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VQE0-1", "url": "https://www.uniprot.org/uniprotkb/Q9VQE0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEALIPVINKLQDVFNTVGSDSIQLPQIVVLGSQSSGKSSVIESVVGRSFLPRGTGIVTRRPLVLQLIYSPLDDRENRSAENGTSNAEEWGRFLHTKKCFTDFDEIRKEIENETERAAGSNKGICPEPINLKIFSTHVVNLTLVDLPGITKVPVGDQPEDIEAQIKELVLKYIENPNSIILAVTAANTDMATSEALKLAKDVDPDGRRTLAVVTKLDLMDAGTDAIDILCGRVIPVKLGIIGVMNRSQKDIMDQKHIDDQMKDEAAFLQRKYPTLATRNGTPYLAKTLNRLLMHHIRDCLPDLKTRVNIMATQFQSLLNSYGEDVSDKSQTLLQIITKFSSAYCCTIEGTARNIETTELCGGARMGYIFHETFGRTLDSIHPLAGLSKMDILTAIRNATGPRPALFVPEVSFELLVKRQIRRLEEPSLRCVELIHEEMQRIVQHCGNEVQQEMLRFPKLHEKIVDVVTQLLRRRLPHTNVMVENIVAIELAYINTKHPDFHKDAALVPSLLKTDSDPYSQINLGQRRANTPRNHMSPQISSHSAGSQQPQQQQPPQPNSSQQQYSQVHEQNHVAENSTPSMASTWLSNILPPAPTRPDSIENSTNNTPVHNNIVSPVKPVNLLPDVPANHNPRRLTDKEQKDCDVIEHLIKSYFYIVRKSIQDSVPKAIMHFLVNYVKDNLQSELVTHLYKSDKAETLLNESDHIAVRRKEAADMLKALTRANHIISEIRETHMW", "length": 735, "header": "tr|Q9VQE0-1|Q9VQE0_DROME Isoform 1 of dynamin GTPase OS=Drosophila melanogaster OX=7227 GN=Drp1 PE=1 SV=1 CANONICAL=Q9VQE0-1" }, "isoforms": [ { "isoform_ac": "Q9VQE0-1", "url": "https://www.uniprot.org/uniprotkb/Q9VQE0/entry#Q9VQE0-1", "sequence": { "sequence": "MEALIPVINKLQDVFNTVGSDSIQLPQIVVLGSQSSGKSSVIESVVGRSFLPRGTGIVTRRPLVLQLIYSPLDDRENRSAENGTSNAEEWGRFLHTKKCFTDFDEIRKEIENETERAAGSNKGICPEPINLKIFSTHVVNLTLVDLPGITKVPVGDQPEDIEAQIKELVLKYIENPNSIILAVTAANTDMATSEALKLAKDVDPDGRRTLAVVTKLDLMDAGTDAIDILCGRVIPVKLGIIGVMNRSQKDIMDQKHIDDQMKDEAAFLQRKYPTLATRNGTPYLAKTLNRLLMHHIRDCLPDLKTRVNIMATQFQSLLNSYGEDVSDKSQTLLQIITKFSSAYCCTIEGTARNIETTELCGGARMGYIFHETFGRTLDSIHPLAGLSKMDILTAIRNATGPRPALFVPEVSFELLVKRQIRRLEEPSLRCVELIHEEMQRIVQHCGNEVQQEMLRFPKLHEKIVDVVTQLLRRRLPHTNVMVENIVAIELAYINTKHPDFHKDAALVPSLLKTDSDPYSQINLGQRRANTPRNHMSPQISSHSAGSQQPQQQQPPQPNSSQQQYSQVHEQNHVAENSTPSMASTWLSNILPPAPTRPDSIENSTNNTPVHNNIVSPVKPVNLLPDVPANHNPRRLTDKEQKDCDVIEHLIKSYFYIVRKSIQDSVPKAIMHFLVNYVKDNLQSELVTHLYKSDKAETLLNESDHIAVRRKEAADMLKALTRANHIISEIRETHMW", "length": 735, "header": "tr|Q9VQE0-1|Q9VQE0_DROME Isoform 1 of dynamin GTPase OS=Drosophila melanogaster OX=7227 GN=Drp1 PE=1 SV=1 CANONICAL=Q9VQE0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VQE0", "url": "https://www.uniprot.org/uniprotkb/Q9VQE0" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VQE0", "url": "https://www.uniprot.org/uniprotkb/Q9VQE0" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQE0", "url": "https://www.uniprot.org/uniprotkb/Q9VQE0" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQE0", "url": "https://www.uniprot.org/uniprotkb/Q9VQE0" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VQE0", "url": "https://www.uniprot.org/uniprotkb/Q9VQE0" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VQE0", "url": "https://www.uniprot.org/uniprotkb/Q9VQE0" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VQE0", "url": "https://www.uniprot.org/uniprotkb/Q9VQE0" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQE0", "url": "https://www.uniprot.org/uniprotkb/Q9VQE0" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQE0", "url": "https://www.uniprot.org/uniprotkb/Q9VQE0" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VQE0", "url": "https://www.uniprot.org/uniprotkb/Q9VQE0" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VQE0", "url": "https://www.uniprot.org/uniprotkb/Q9VQE0" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG3210", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3210", "resource": "KEGG Pathway" }, { "id": "R-DME-75153", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-75153", "resource": "Reactome", "description": "Apoptotic execution phase" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M3APM4-1", "protein_name": "Myxovirus (Influenza virus) resistance G isoform X1", "gene_name": "mxg", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSVSKQSVFSMFSSSFTSTRSSDDPKNSHYESQQMREVHSHLEESIRPYIDLIDTLRSVGIHKDLALPTIVVIGDQSSGKSSVLETLSGVALPRGNGIVTRCPLELRLKKVTGGVSWKAVISYREKRTEFADPSMVERHVKTAQDELAGNGVGICDELITLEVMSPDVCNLTLIDLPGIARVPVAGQPDDIANQIKKLIIKFIVMQETINLVVVPCNIDIATTEALKLAQEVDPEGKRTIAVLTKPDLIDKGTEKNILAIVQNKVIPLRKGYVMVKCRGQQQIDDDISLDEATEMEKEFFQNHEFFRRLLSEDKATTKSLANKLTQNLVDHIKKSLPQLSEQIKKQLWDLRDDLKECESGPPQDSKGAKQFLIKILTKFNGRIKLLSSGEKMAEKNLFVLLREEFNMWNDHLNETKKSLKQSTKEKIEVLQNFRGRELPGFSNYRVFEVILQNHVATLKNPASKLLNAIKGIILDHFTEVVETCFQNYPNLQSITKDKIDNIQSSQQAKAEQRISEQFKMERMIFTQDPIFLKALNEIPDSETFSIDELPVFDKKSKYSDMLEAYYEIVVQRMADQLPMMILFFMLKQTAKLLTADMLSLLKGVKVSELLFEDTDVSRRRRDLQARLDRLSIAQETLSNFEGSAE", "length": 645 }, "evidence": [ { "id": "SGD:S000001709", "url": "https://alliancegenome.org/gene/SGD:S000001709#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58GC78-1", "protein_name": "Dynamin-1-like protein", "gene_name": "si:dkey-32e23.4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVSSSCAWADFRYREEELTKASGFELGEERFQKPEMETLIPIINRLQEVFLTVGAEIIQLPQIVVVGSQSSGKSSVLESLVGRDFLPRGSGIVTRRPLVLQLVNVPPLEERRKQDNGNGSKQNSQNNYPGIKAEEWGTFLHCKNQIFTDFNEIRKEIEEETDRSTNNKGISKEPIYLKIYSPNVLSLTLVDLPGITKVPVGDQPEDIEIQVQEMILSYISNPNSLILCVSPANSDLATSDALKLAREVDADGRRTLLVVSKLDLMDAGTDALEVLLGRVIPVRLGIIGVVNRSQHDLNTQKSLSDSCRDEQAFLQRHYPSLASRCGSRYLARTLSRLLMHHIRDCLPELKTRVTVLTAQYQSRLNSYGQPVEDHSATLLQIVTKFATDYCSTIEGTARHIQTSELCGGARMCYIFHETFGRTLQSIDPLGGLTELDILTAIRNATGPRPALFVPEVSFELLVKKQIKRLEEPSLRCVELVHEELQRIIQHCSSYSTQELLRFPKLHDSIVEVVTGLLRKRLPITNEMVHNLVAIELAYINTKHPDFTDAAQVSASVNSQQAEAGDGGKRWKNEKMPSEEKGPMPGFGSPSKAINLLDTAVPVSRKLSSREQRDCEVIQRLIKCYFLIVRKSIQDSVPKTVMHFLVNFVKEHLQSELVGQLYKQPLLQELLIESQETAQQRTEVAHMLEALKKASNIISEIRETHLW", "length": 706 }, "evidence": [ { "id": "FB:FBgn0026479", "url": "https://alliancegenome.org/gene/FB:FBgn0026479#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081105-41", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081105-41#orthology", "database": "AGR" }, { "id": "SGD:S000003924", "url": "https://alliancegenome.org/gene/SGD:S000003924#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O00429-1", "protein_name": "Dynamin-1-like protein", "gene_name": "DNM1L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTRRPLILQLVHVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIENETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAMDVLMGRVIPVKLGIIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLARTLNRLLMHHIRDCLPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNTIEGTAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLRKRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSAVSRDKSSKVPSALAPASQEPSPAASAEADGKLIQDSRRETKNVASGGGGVGDGVQEPTTGNWRGMLKTSKAEELLAEEKSKPIPIMPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMAQRRKEAADMLKALQGASQIIAEIRETHLW", "length": 736 }, "evidence": [ { "id": "FB:FBgn0026479", "url": "https://alliancegenome.org/gene/FB:FBgn0026479#orthology", "database": "AGR" }, { "id": "MGI:1921256", "url": "https://alliancegenome.org/gene/MGI:1921256#orthology", "database": "AGR" }, { "id": "HGNC:2973", "url": "https://alliancegenome.org/gene/HGNC:2973#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1556", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1556#orthology", "database": "AGR" }, { "id": "RGD:620416", "url": "https://alliancegenome.org/gene/RGD:620416#orthology", "database": "AGR" }, { "id": "SGD:S000003924", "url": "https://alliancegenome.org/gene/SGD:S000003924#orthology", "database": "AGR" }, { "id": "Q9VQE0", "url": "https://omabrowser.org/oma/group/Q9VQE0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O35303-1", "protein_name": "Dynamin-1-like protein", "gene_name": "Dnm1l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGVVTRRPLILQLVHVSPEDKRKTTGEENDPATWKNSRHLSKGVEAEEWGKFLHTKNKLYTDFDEIRQEIENETERISGNNKGVSPEPIHLKVFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAMDVLMGRVIPVKLGIIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLARTLNRLLMHHIRDCLPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNTIEGTAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLRKRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSAVSRDKSSKVPSALAPASQEPSPAASAEADGKLIQDNRRETKNVASAGGGIGDGGRIGDGGQEPTTGNWRGMLKTSKAEELLAEEKSKPIPIMPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMAQRRKEAADMLKALQGASQIIAEIRETHLW", "length": 755 }, "evidence": [ { "id": "FB:FBgn0026479", "url": "https://alliancegenome.org/gene/FB:FBgn0026479#orthology", "database": "AGR" }, { "id": "MGI:1921256", "url": "https://alliancegenome.org/gene/MGI:1921256#orthology", "database": "AGR" }, { "id": "HGNC:2973", "url": "https://alliancegenome.org/gene/HGNC:2973#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1556", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1556#orthology", "database": "AGR" }, { "id": "RGD:620416", "url": "https://alliancegenome.org/gene/RGD:620416#orthology", "database": "AGR" }, { "id": "SGD:S000003924", "url": "https://alliancegenome.org/gene/SGD:S000003924#orthology", "database": "AGR" }, { "id": "Q9VQE0", "url": "https://omabrowser.org/oma/group/Q9VQE0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P18588-1", "protein_name": "Interferon-induced GTP-binding protein Mx1", "gene_name": "Mx1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKERTSACRHGTPQKHPDTSEESQAMESVDNLCSQYEEKVRPCIDLIDSLRALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLKQLKQGEKWSGKVIYKDTEIEISHPSLVEREINKAQNLIAGEGLKISSDLISLEVSSPHVPDLTLIDLPGITRVAVGDQPADIEHKIKRLITEYIQKQETINLVVVPSNVDIATTEALKMAQEVDPQGDRTIGILTKPDLVDRGTEDKVVDVVRNLVCHLKKGYMIVKCRGQQDIQEQLSLAEALQKEQVFFKEHPQFRVLLEDGKATVPCLAKRLTMELTSHICKSLPILENQINVNHQIASEELQKYGADIPEDDSKRLSFLMNKINVFNKDILSLVQAQENISWEESRLFTKLRNEFLAWNDYIEEHFKKTLGSSEKHSQMEKFESHYRGRELPGFVDYKAFENIIKKEVKALEEPALNMLHRVTTMVKNAFTKVSSNNFGDFLNLHSTAKSKIEDIRFNQEKEAEKLIRLHFQMEHIVYCQDQAYKKALQEIREKEAEKEKSTFGAFQHNSPRKELTTTEMTQHLNAYYQECGRNIGRQIPLIIQYSILQTFGQEMEKAMLQLLQDTSKCNWFLTEQSDSREKKKFLKRRLLRLDEAQRKLAKFSN", "length": 652 }, "evidence": [ { "id": "SGD:S000001709", "url": "https://alliancegenome.org/gene/SGD:S000001709#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P20591-1", "protein_name": "Interferon-induced GTP-binding protein Mx1", "gene_name": "MX1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVSEVDIAKADPAAASHPLLLNGDATVAQKNPGSVAENNLCSQYEEKVRPCIDLIDSLRALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLKKLVNEDKWRGKVSYQDYEIEISDASEVEKEINKAQNAIAGEGMGISHELITLEISSRDVPDLTLIDLPGITRVAVGNQPADIGYKIKTLIKKYIQRQETISLVVVPSNVDIATTEALSMAQEVDPEGDRTIGILTKPDLVDKGTEDKVVDVVRNLVFHLKKGYMIVKCRGQQEIQDQLSLSEALQREKIFFENHPYFRDLLEEGKATVPCLAEKLTSELITHICKSLPLLENQIKETHQRITEELQKYGVDIPEDENEKMFFLIDKVNAFNQDITALMQGEETVGEEDIRLFTRLRHEFHKWSTIIENNFQEGHKILSRKIQKFENQYRGRELPGFVNYRTFETIVKQQIKALEEPAVDMLHTVTDMVRLAFTDVSIKNFEEFFNLHRTAKSKIEDIRAEQEREGEKLIRLHFQMEQIVYCQDQVYRGALQKVREKELEEEKKKKSWDFGAFQSSSATDSSMEEIFQHLMAYHQEASKRISSHIPLIIQFFMLQTYGQQLQKAMLQLLQDKDTYSWLLKERSDTSDKRKFLKERLARLTQARRRLAQFPG", "length": 662 }, "evidence": [ { "id": "SGD:S000001709", "url": "https://alliancegenome.org/gene/SGD:S000001709#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P20592-1", "protein_name": "Interferon-induced GTP-binding protein Mx2", "gene_name": "MX2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSKAHKPWPYRRRSQFSSRKYLKKEMNSFQQQPPPFGTVPPQMMFPPNWQGAEKDAAFLAKDFNFLTLNNQPPPGNRSQPRAMGPENNLYSQYEQKVRPCIDLIDSLRALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLKKQPCEAWAGRISYRNTELELQDPGQVEKEIHKAQNVMAGNGRGISHELISLEITSPEVPDLTIIDLPGITRVAVDNQPRDIGLQIKALIKKYIQRQQTINLVVVPCNVDIATTEALSMAHEVDPEGDRTIGILTKPDLMDRGTEKSVMNVVRNLTYPLKKGYMIVKCRGQQEITNRLSLAEATKKEITFFQTHPYFRVLLEEGSATVPRLAERLTTELIMHIQKSLPLLEGQIRESHQKATEELRRCGADIPSQEADKMFFLIEKIKMFNQDIEKLVEGEEVVRENETRLYNKIREDFKNWVGILATNTQKVKNIIHEEVEKYEKQYRGKELLGFVNYKTFEIIVHQYIQQLVEPALSMLQKAMEIIQQAFINVAKKHFGEFFNLNQTVQSTIEDIKVKHTAKAENMIQLQFRMEQMVFCQDQIYSVVLKKVREEIFNPLGTPSQNMKLNSHFPSNESSVSSFTEIGIHLNAYFLETSKRLANQIPFIIQYFMLRENGDSLQKAMMQILQEKNRYSWLLQEQSETATKRRILKERIYRLTQARHALCQFSSKEIH", "length": 715 }, "evidence": [ { "id": "SGD:S000001709", "url": "https://alliancegenome.org/gene/SGD:S000001709#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P21576-1", "protein_name": "Vacuolar protein sorting-associated protein 1", "gene_name": "VPS1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDEHLISTINKLQDALAPLGGGSQSPIDLPQITVVGSQSSGKSSVLENIVGRDFLPRGTGIVTRRPLVLQLINRRPKKSEHAKVNQTANELIDLNINDDDKKKDESGKHQNEGQSEDNKEEWGEFLHLPGKKFYNFDEIRKEIVKETDKVTGANSGISSVPINLRIYSPHVLTLTLVDLPGLTKVPVGDQPPDIERQIKDMLLKYISKPNAIILSVNAANTDLANSDGLKLAREVDPEGTRTIGVLTKVDLMDQGTDVIDILAGRVIPLRYGYIPVINRGQKDIEHKKTIREALENERKFFENHPSYSSKAHYCGTPYLAKKLNSILLHHIRQTLPEIKAKIEATLKKYQNELINLGPETMDSASSVVLSMITDFSNEYAGILDGEAKELSSQELSGGARISYVFHETFKNGVDSLDPFDQIKDSDIRTIMYNSSGSAPSLFVGTEAFEVLVKQQIRRFEEPSLRLVTLVFDELVRMLKQIISQPKYSRYPALREAISNQFIQFLKDATIPTNEFVVDIIKAEQTYINTAHPDLLKGSQAMVMVEEKLHPRQVAVDPKTGKPLPTQPSSSKAPVMEEKSGFFGGFFSTKNKKKLAALESPPPVLKATGQMTERETMETEVIKLLISSYFSIVKRTIADIIPKALMLKLIVKSKTDIQKVLLEKLYGKQDIEELTKENDITIQRRKECKKMVEILRNASQIVSSV", "length": 704 }, "evidence": [ { "id": "FB:FBgn0026479", "url": "https://alliancegenome.org/gene/FB:FBgn0026479#orthology", "database": "AGR" }, { "id": "SGD:S000001709", "url": "https://alliancegenome.org/gene/SGD:S000001709#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P54861-1", "protein_name": "Dynamin-related protein DNM1", "gene_name": "DNM1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MASLEDLIPTVNKLQDVMYDSGIDTLDLPILAVVGSQSSGKSSILETLVGRDFLPRGTGIVTRRPLVLQLNNISPNSPLIEEDDNSVNPHDEVTKISGFEAGTKPLEYRGKERNHADEWGEFLHIPGKRFYDFDDIKREIENETARIAGKDKGISKIPINLKVFSPHVLNLTLVDLPGITKVPIGEQPPDIEKQIKNLILDYIATPNCLILAVSPANVDLVNSESLKLAREVDPQGKRTIGVITKLDLMDSGTNALDILSGKMYPLKLGFVGVVNRSQQDIQLNKTVEESLDKEEDYFRKHPVYRTISTKCGTRYLAKLLNQTLLSHIRDKLPDIKTKLNTLISQTEQELARYGGVGATTNESRASLVLQLMNKFSTNFISSIDGTSSDINTKELCGGARIYYIYNNVFGNSLKSIDPTSNLSVLDVRTAIRNSTGPRPTLFVPELAFDLLVKPQIKLLLEPSQRCVELVYEELMKICHKCGSAELARYPKLKSMLIEVISELLRERLQPTRSYVESLIDIHRAYINTNHPNFLSATEAMDDIMKTRRKRNQELLKSKLSQQENGQTNGINGTSSISSNIDQDSAKNSDYDDDGIDAESKQTKDKFLNYFFGKDKKGQPVFDASDKKRSIAGDGNIEDFRNLQISDFSLGDIDDLENAEPPLTEREELECELIKRLIVSYFDIIREMIEDQVPKAVMCLLVNYCKDSVQNRLVTKLYKETLFEELLVEDQTLAQDRELCVKSLGVYKKAATLISNIL", "length": 757 }, "evidence": [ { "id": "FB:FBgn0026479", "url": "https://alliancegenome.org/gene/FB:FBgn0026479#orthology", "database": "AGR" }, { "id": "MGI:1921256", "url": "https://alliancegenome.org/gene/MGI:1921256#orthology", "database": "AGR" }, { "id": "HGNC:2973", "url": "https://alliancegenome.org/gene/HGNC:2973#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1556", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1556#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081105-41", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081105-41#orthology", "database": "AGR" }, { "id": "RGD:620416", "url": "https://alliancegenome.org/gene/RGD:620416#orthology", "database": "AGR" }, { "id": "SGD:S000003924", "url": "https://alliancegenome.org/gene/SGD:S000003924#orthology", "database": "AGR" }, { "id": "Q9VQE0", "url": "https://omabrowser.org/oma/group/Q9VQE0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q2KIA5-1", "protein_name": "Dynamin-1-like protein", "gene_name": "DNM1L", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTRRPLILQLVHVAPEDKRKTTGEENDPATWKNSRHLSKGVEAEEWGKFLHTKNKLYTDFDEIRQEIENETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAMDVLMGRVIPVKLGIIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLARTLNRLLMHHIRDCLPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNTIEGTAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLRKRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSAVSRDKSSKVPSALAPASQEPSPAASAEADGKLIQESRRETKNAASGGGGVGDAVQEPTTGNWRGMLKTSKAEELLAEEKSKPIPIMPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMAQRRKEAADMLKALQGASQIIAEIRETHLW", "length": 749 }, "evidence": [ { "id": "Q9VQE0", "url": "https://omabrowser.org/oma/group/Q9VQE0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6DKF0-1", "protein_name": "Interferon-induced GTP-binding protein MxC", "gene_name": "mxc", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSSFDSAEGECNGLNQHYEKKVRPIIDLVDTLRALGVEKDLNLPAIAVIGDQSSGKSSVLEALSGVALPRGIGIVTRCPLILKLKKITRDKNWSGLLTYKDQTEILKEPTGIENAVLKAQIALAGTGEGISHEMITLEIQSCDVPDLTLIDLPGIARVATGNQPEDIEKQIKDLIEKFIKRQETISLVVVPANIDIATTEALKMASTVDPTGQRTLCILTKPDLVDRGMEDTVVRTVNNEVIRLEKGYMIVKCRGQQDINDKLNLVEALEKERRFFDEHPQFSSLLEDGKATIPLLGQRLTEELVEHIAKNVPRLQNQIEMKLQKTFERLKVLGESVPDDDEIELNNFLIKKLRQFMDALEEVKRVEEEPVKSDTRVFSKIRQEFVSWKHILDSKPIKMSTDLQEYVRTHRGKELPGFLNYGTFAGIIRMHVEDLEEPALKLLRNAKDIVHSSVGSIANIHFNGYPNLLLAVKEPIEKCLHEQFQNAEEKIRSQFKLEKTVYCQDDLYTNHLNLLRPKNTVRFGLEASLGNSELRETAFHLTSYLTIACERLANQIPLIVQYHMMNEYNSQLQNAMLGLIGTSDPGMLLCEDSGVARIRKDLKERLERLKDARRALPKVVHSANSW", "length": 626 }, "evidence": [ { "id": "SGD:S000001709", "url": "https://alliancegenome.org/gene/SGD:S000001709#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q7SXN5-1", "protein_name": "Dynamin-1-like protein", "gene_name": "dnm1l", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEALIPVINKLQDVFNTVGADIIQLPQIAVVGTQSSGKSSVLESLVGRDLLPRGTGIVTRRPLILQLVHVDPEDRRKTSEENGVDGEEWGKFLHTKNKIYTDFDEIRQEIENETERVSGNNKGISDEPIHLKIFSPHVVNLTLVDLPGITKVPVGDQPKDIELQIRELILKYISNPNSIILAVTAANTDMATSEALKVAREVDPDGRRTLAVVTKLDLMDAGTDAMDVLMGRVIPVKLGLIGVVNRSQLDINNKKSVADSIRDEHGFLQKKYPSLANRNGTKYLARTLNRLLMHHIRDCLPELKTRINVLSAQYQSLLSSYGEPVEDMSATLLQLITKFATEYCNTIEGTAKYIETAELCGGARICYIFHETFGRTLESVDPLGGLTTIDVLTAIRNATGPRPALFVPEVSFELLVKRQVKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTSLLRKRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRMRELPTSVPRDKMAGGAQAEQEGGTGTWRGMLKKGDEGQGEEKTKLQSSIPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDSLQSELVGQLYKPALLDDLLTESEDMAQRRNEAADMLKALQKASQVIAEIRETHLW", "length": 691 }, "evidence": [ { "id": "FB:FBgn0026479", "url": "https://alliancegenome.org/gene/FB:FBgn0026479#orthology", "database": "AGR" }, { "id": "MGI:1921256", "url": "https://alliancegenome.org/gene/MGI:1921256#orthology", "database": "AGR" }, { "id": "HGNC:2973", "url": "https://alliancegenome.org/gene/HGNC:2973#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1556", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1556#orthology", "database": "AGR" }, { "id": "RGD:620416", "url": "https://alliancegenome.org/gene/RGD:620416#orthology", "database": "AGR" }, { "id": "SGD:S000003924", "url": "https://alliancegenome.org/gene/SGD:S000003924#orthology", "database": "AGR" }, { "id": "Q9VQE0", "url": "https://omabrowser.org/oma/group/Q9VQE0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8JH68-1", "protein_name": "Interferon-induced GTP-binding protein MxA", "gene_name": "mxa", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEKLSYTFSQQYEEKIRPCIDTIDNLRSLGVEKDLALPAIAVIGDQSSGKSSVLEALSGVPLPRGSGIVTRCPLELKMIRTKDQDRWHGRISYKTCEEDFDDPAEVEKKIRQAQDEMAGAGVGISEELISLQITSADVPDLTLIDLPGIARVAVKGQPENIGDQIKRLIRKFVTRQETINLVVVPCNVDIATTEALQMAQAEDPDGERTLGILTKPDLVDKGTEGTVVDIVHNEVIHLTKGYMIVRCRGQKEIMDQVTLNEATETESAFFKDHPHFSKLYEEGFATIPKLAEKLTIELVHHIQKSLPRLEEQIETKLAETQKELEAYGNGPPSEPAARLSFFIDKVTAFNQDMLNLTTGEDVKCTTDLLLFPELRQEFAKWSHILDRSGDSFNKKIEKEVDNYEVKYRGRELPGFINYKTFEGLVRDQIKLLEEPALKTLKTVSDVVRKKFIQLAQCSFIGFPNLLKIAKTKIEGIKLNKESLAESMLKTQFKMELIVYSQDGTYSQSLKHAKDKLEEMEKERPQPKIKLPLLSSFDLGTDNHATLREMRLHLKSYYTIASKRLADQIPMVIRYMLLQEAALELQRNMLQLLQDKDGVDNLLKEDCDIGQKRENLLSRQTRLIEGTQPLGHLLEVTFIDYCNILMQ", "length": 646 }, "evidence": [ { "id": "SGD:S000001709", "url": "https://alliancegenome.org/gene/SGD:S000001709#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8K1M6-12", "protein_name": "Dynamin-1-like protein", "gene_name": "Dnm1l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGVVTRRPLILQLVHVSPEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIENETERISGNNKGVSPEPIHLKVFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAMDVLMGRVIPVKLGIIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLARTLNRLLMHHIRDCLPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNTIEGTAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLRKRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSAGSRDKSSKVPSALAPASQEPPPAASAEADGKLIQDNRRETKNVPSAGGGIGDGGQEPTTGNWRGMLKTSKAEELLAEEKSKPIPIMPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMAQRRKEAADMLKALQGASQIIAEIRETHLW", "length": 736 }, "evidence": [ { "id": "FB:FBgn0026479", "url": "https://alliancegenome.org/gene/FB:FBgn0026479#orthology", "database": "AGR" }, { "id": "MGI:1921256", "url": "https://alliancegenome.org/gene/MGI:1921256#orthology", "database": "AGR" }, { "id": "HGNC:2973", "url": "https://alliancegenome.org/gene/HGNC:2973#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1556", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1556#orthology", "database": "AGR" }, { "id": "RGD:620416", "url": "https://alliancegenome.org/gene/RGD:620416#orthology", "database": "AGR" }, { "id": "SGD:S000003924", "url": "https://alliancegenome.org/gene/SGD:S000003924#orthology", "database": "AGR" }, { "id": "Q9VQE0", "url": "https://omabrowser.org/oma/group/Q9VQE0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8S944-1", "protein_name": "Dynamin-related protein 3A", "gene_name": "DRP3A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MTIEEVSGETPPSTPPSSSTPSPSSSTTNAAPLGSSVIPIVNKLQDIFAQLGSQSTIALPQVVVVGSQSSGKSSVLEALVGRDFLPRGNDICTRRPLVLQLLQTKSRANGGSDDEWGEFRHLPETRFYDFSEIRREIEAETNRLVGENKGVADTQIRLKISSPNVLNITLVDLPGITKVPVGDQPSDIEARIRTMILSYIKQDTCLILAVTPANTDLANSDALQIASIVDPDGHRTIGVITKLDIMDKGTDARKLLLGNVVPLRLGYVGVVNRCQEDILLNRTVKEALLAEEKFFRSHPVYHGLADRLGVPQLAKKLNQILVQHIKVLLPDLKSRISNALVATAKEHQSYGELTESRAGQGALLLNFLSKYCEAYSSLLEGKSEEMSTSELSGGARIHYIFQSIFVKSLEEVDPCEDLTDDDIRTAIQNATGPRSALFVPDVPFEVLVRRQISRLLDPSLQCARFIFEELIKISHRCMMNELQRFPVLRKRMDEVIGDFLREGLEPSEAMIGDIIDMEMDYINTSHPNFIGGTKAVEAAMHQVKSSRIPHPVARPKDTVEPDRTSSSTSQVKSRSFLGRQANGIVTDQGVVSADAEKAQPAANASDTRWGIPSIFRGGDTRAVTKDSLLNKPFSEAVEDMSHNLSMIYLKEPPAVLRPTETHSEQEAVEIQITKLLLRSYYDIVRKNIEDSVPKAIMHFLVNHTKRELHNVFIKKLYRENLFEEMLQEPDEIAVKRKRTQETLHVLQQAYRTLDELPLEADSVSAGMSKHQELLTSSKYSTSSSYSASPSTTRRSRRAGDQHQNGYGF", "length": 808 }, "evidence": [ { "id": "Q9VQE0", "url": "https://omabrowser.org/oma/group/Q9VQE0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9WVP9-1", "protein_name": "Interferon-induced GTP-binding protein Mx2", "gene_name": "Mx2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLSTEENTGVDSVNLPSGETGLGEKDQESVNNLCSQYEEKVRPCIDLIDSLRALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLRKLNEGEEWRGKVSYDDIEVELSDPSEVEEAINKGQNFIAGVGLGISDKLISLDVSSPNVPDLTLIDLPGITRVAVGNQPADIGRQIKRLIKTYIQKQETINLVVVPSNVDIATTEALSMAQEVDPEGDRTIGILTKPDLVDRGTEDKVVDVVRNLVYHLKKGYMIVKCRGQQDIQEQLSLTEALQNEQIFFKEHPHFRVLLEDGKATVPCLAERLTAELISHICKSLPLLENQIKESHQSASEELQKYGMDIPEDDSEKTFFLIEKINAFNQDITALVQGEENVAEGECRLFTRLRKEFLSWSKEIEKNFAKGYAVLYNEVWAFEKQYRGRELPGFVNYKTFENIIRRQIKTLEEPAIEMLHTVTEIVRAAFTSVSEKNFSEFYNLHRTTKSKLEDIRLEQEKEAEMSIRLHFKMEQIIYCQDQIYRGALQKVREEEAEEEKKTKHGTSSSSQSQDLQTSSMAEIFQHLNAYRQEAHNRISSHVPLIIQYFILKMFAERLQKGMLQLLQDKDSCSWLLKEQSDTSEKRKFLKERLARLAQARRRLAKFPG", "length": 655 }, "evidence": [ { "id": "SGD:S000001709", "url": "https://alliancegenome.org/gene/SGD:S000001709#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 10, "go_terms": [ { "name": "sperm mitochondrion organization", "id": "GO:0030382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030382", "evidence": [ { "database": "UniProtKB", "id": "Q9VQE0", "url": "https://www.uniprot.org/uniprotkb/Q9VQE0" } ], "pmid": "" }, { "name": "regulation of mitochondrial fission", "id": "GO:0090140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090140", "evidence": [ { "database": "UniProtKB", "id": "Q9VQE0", "url": "https://www.uniprot.org/uniprotkb/Q9VQE0" } ], "pmid": "" }, { "name": "peroxisome fission", "id": "GO:0016559", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016559", "evidence": [ { "database": "UniProtKB", "id": "Q9VQE0", "url": "https://www.uniprot.org/uniprotkb/Q9VQE0" } ], "pmid": "" }, { "name": "mitochondrion organization", "id": "GO:0007005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007005", "evidence": [ { "database": "UniProtKB", "id": "Q9VQE0", "url": "https://www.uniprot.org/uniprotkb/Q9VQE0" } ], "pmid": "" }, { "name": "mitochondrion localization", "id": "GO:0051646", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051646", "evidence": [ { "database": "UniProtKB", "id": "Q9VQE0", "url": "https://www.uniprot.org/uniprotkb/Q9VQE0" } ], "pmid": "" }, { "name": "mitochondrial fission", "id": "GO:0000266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000266", "evidence": [ { "database": "UniProtKB", "id": "Q9VQE0", "url": "https://www.uniprot.org/uniprotkb/Q9VQE0" } ], "pmid": "" }, { "name": "intracellular distribution of mitochondria", "id": "GO:0048312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048312", "evidence": [ { "database": "UniProtKB", "id": "Q9VQE0", "url": "https://www.uniprot.org/uniprotkb/Q9VQE0" } ], "pmid": "" }, { "name": "positive regulation of mitochondrial fission", "id": "GO:0090141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090141", "evidence": [ { "database": "UniProtKB", "id": "Q9VQE0", "url": "https://www.uniprot.org/uniprotkb/Q9VQE0" } ], "pmid": "" }, { "name": "lymph gland crystal cell differentiation", "id": "GO:0035170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035170", "evidence": [ { "database": "UniProtKB", "id": "Q9VQE0", "url": "https://www.uniprot.org/uniprotkb/Q9VQE0" } ], "pmid": "" }, { "name": "ventral furrow formation", "id": "GO:0007370", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007370", "evidence": [ { "database": "UniProtKB", "id": "Q9VQE0", "url": "https://www.uniprot.org/uniprotkb/Q9VQE0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "Q9VQE0", "url": "https://www.uniprot.org/uniprotkb/Q9VQE0" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "Q9VQE0", "url": "https://www.uniprot.org/uniprotkb/Q9VQE0" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "Q9VQE0", "url": "https://www.uniprot.org/uniprotkb/Q9VQE0" } ], "pmid": "" }, { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "Q9VQE0", "url": "https://www.uniprot.org/uniprotkb/Q9VQE0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VQE0", "url": "https://www.uniprot.org/uniprotkb/Q9VQE0" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9VQE0", "url": "https://www.uniprot.org/uniprotkb/Q9VQE0" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "Q9VQE0", "url": "https://www.uniprot.org/uniprotkb/Q9VQE0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VQE0", "url": "https://www.uniprot.org/uniprotkb/Q9VQE0" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "Q9VQE0", "url": "https://www.uniprot.org/uniprotkb/Q9VQE0" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VQE0", "url": "https://www.uniprot.org/uniprotkb/Q9VQE0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 112, "end_pos": 114, "annotation": "n_glycosylation_sequon" }, { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 245, "end_pos": 247, "annotation": "n_glycosylation_sequon" }, { "start_pos": 279, "end_pos": 281, "annotation": "n_glycosylation_sequon" }, { "start_pos": 397, "end_pos": 399, "annotation": "n_glycosylation_sequon" }, { "start_pos": 558, "end_pos": 560, "annotation": "n_glycosylation_sequon" }, { "start_pos": 576, "end_pos": 578, "annotation": "n_glycosylation_sequon" }, { "start_pos": 602, "end_pos": 604, "annotation": "n_glycosylation_sequon" }, { "start_pos": 605, "end_pos": 607, "annotation": "n_glycosylation_sequon" }, { "start_pos": 700, "end_pos": 702, "annotation": "n_glycosylation_sequon" }, { "start_pos": 77, "end_pos": 79, "annotation": "n_glycosylation_sequon" }, { "start_pos": 82, "end_pos": 84, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P27619-1", "P08645-1", "P08646-1", "P40793-1", "Q24208-1", "P04388-1", "Q7YU24-1", "P48555-1", "Q9VRH6-1", "O18412-1", "A1Z9N0-1", "P06604-1", "P06606-1", "P61209-1", "P06603-1", "P06605-1", "Q9W074-1", "O18333-1", "P13060-1", "Q9VQE0-1", "O96692-1", "Q9VND8-1", "Q9V3I2-1", "O76742-1", "Q9VNG6-1", "Q86BK8-1", "Q9VRY2-1", "Q9VC57-1", "Q9VM20-1", "Q9VP48-1", "Q9VIW6-1", "Q9W0A7-1", "Q9VM50-1", "P48148-1", "Q24192-1", "Q9V3R3-1", "Q0E931-1", "P40792-1", "O18339-1" ], "evidence": [ { "id": "19669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19669" } ] }, { "id": "R-DME-351948", "name": "Mitochondrial recruitment of Drp1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, mitochondrial outer membrane", "input_participant_list": [ "R-DME-351943" ], "output_participant_list": [ "R-DME-351942" ], "enzyme_list": [ "Q9VQE0-1" ], "evidence": [ { "id": "R-DME-351948", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-351948" } ] } ], "reaction_participants": [ { "participant_id": "R-DME-351942", "participant_name": "Drp1 [mitochondrial outer membrane]", "crossref": [ { "id": "FBgn0026479", "database": "FlyBase", "url": "" }, { "id": "NP_001259946.1", "database": "RefSeq", "url": "" }, { "id": "NP_608694.2", "database": "RefSeq", "url": "" }, { "id": "Q9VQE0", "database": "UniProt", "url": "" } ] }, { "participant_id": "R-DME-351943", "participant_name": "Drp1 [cytosol]", "crossref": [ { "id": "Q9VQE0", "database": "UniProt", "url": "" }, { "id": "FBgn0026479", "database": "FlyBase", "url": "" }, { "id": "NP_608694.2", "database": "RefSeq", "url": "" }, { "id": "NP_001259946.1", "database": "RefSeq", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A1Z9N0", "gene_name": "Opa1", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A1Z9N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1Z9N0" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A1Z9N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1Z9N0" } ] } ] }, { "uniprot_ac": "O18333", "gene_name": "Rab2", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "O18333", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O18333" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "O18333", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O18333" } ] } ] }, { "uniprot_ac": "O18339", "gene_name": "Rab19", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "O18339", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O18339" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "O18339", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O18339" } ] } ] }, { "uniprot_ac": "O18412", "gene_name": "fzo", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "O18412", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O18412" } ] } ] }, { "uniprot_ac": "O76742", "gene_name": "Rab7", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "O76742", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O76742" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "O76742", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O76742" } ] } ] }, { "uniprot_ac": "O96692", "gene_name": "Rap2l", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "O96692", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O96692" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "O96692", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O96692" } ] } ] }, { "uniprot_ac": "P04388", "gene_name": "Ras64B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "P04388", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04388" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "P04388", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04388" } ] } ] }, { "uniprot_ac": "P06603", "gene_name": "alphaTub84B", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "P06603", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P06603" } ] } ] }, { "uniprot_ac": "P06604", "gene_name": "alphaTub85E", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "P06604", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P06604" } ] } ] }, { "uniprot_ac": "P06605", "gene_name": "alphaTub84D", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "P06605", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P06605" } ] } ] }, { "uniprot_ac": "P06606", "gene_name": "alphaTub67C", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "P06606", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P06606" } ] } ] }, { "uniprot_ac": "P08645", "gene_name": "Rap1", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "P08645", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08645" } ] }, { 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"url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050235", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050235", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG9962", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG9962", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HIPFKWG", "url": "https://omabrowser.org/oma/group/HIPFKWG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VQE3", "url": "https://www.orthodb.org/?gene=Q9VQE3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11909", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11909", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_608697", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608697", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VQE3", "url": "https://www.uniprot.org/uniprotkb/Q9VQE3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VQE3-1", "url": "https://www.uniprot.org/uniprotkb/Q9VQE3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNDYELETMLRINSIMVIRKLGSGSFGDIYEAKHMGSGLHVALKVERKNAGQSHLSIESTVYNLLRHGMGIPMTYQFFSNRRHDVLVMELLGPSLETLFTMCNRRFSMKTVLMLADQMVDRLEYLHLHHYVHRDIKPENFLMGVGLTRHRLHLIDFGLSKRYWDMKENRHVPQRRGTKWAGTARYASVNALCCKVQSRRDDLESVGYVLIYLLRGSLPWQGLLPNSKLQKAEMILEMKLSTLPNSLCAGYPNEFYNYIIYTRQLGFEEEPDYRMIRCTFLSLLFNLKFTNDLIYDWDHAEKNSGKSGSEEDRVVVKKVV", "length": 319, "header": "tr|Q9VQE3-1|Q9VQE3_DROME Isoform 1 of non-specific serine/threonine protein kinase OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG9962 PE=3 SV=1 CANONICAL=Q9VQE3-1" }, "isoforms": [ { "isoform_ac": "Q9VQE3-1", "url": "https://www.uniprot.org/uniprotkb/Q9VQE3/entry#Q9VQE3-1", "sequence": { "sequence": "MNDYELETMLRINSIMVIRKLGSGSFGDIYEAKHMGSGLHVALKVERKNAGQSHLSIESTVYNLLRHGMGIPMTYQFFSNRRHDVLVMELLGPSLETLFTMCNRRFSMKTVLMLADQMVDRLEYLHLHHYVHRDIKPENFLMGVGLTRHRLHLIDFGLSKRYWDMKENRHVPQRRGTKWAGTARYASVNALCCKVQSRRDDLESVGYVLIYLLRGSLPWQGLLPNSKLQKAEMILEMKLSTLPNSLCAGYPNEFYNYIIYTRQLGFEEEPDYRMIRCTFLSLLFNLKFTNDLIYDWDHAEKNSGKSGSEEDRVVVKKVV", "length": 319, "header": "tr|Q9VQE3-1|Q9VQE3_DROME Isoform 1 of non-specific serine/threonine protein kinase OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG9962 PE=3 SV=1 CANONICAL=Q9VQE3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VQE3", "url": "https://www.uniprot.org/uniprotkb/Q9VQE3" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VQE3", "url": "https://www.uniprot.org/uniprotkb/Q9VQE3" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQE3", "url": "https://www.uniprot.org/uniprotkb/Q9VQE3" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQE3", "url": "https://www.uniprot.org/uniprotkb/Q9VQE3" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VQE3", "url": "https://www.uniprot.org/uniprotkb/Q9VQE3" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VQE3", "url": "https://www.uniprot.org/uniprotkb/Q9VQE3" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VQE3", "url": "https://www.uniprot.org/uniprotkb/Q9VQE3" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQE3", "url": "https://www.uniprot.org/uniprotkb/Q9VQE3" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQE3", "url": "https://www.uniprot.org/uniprotkb/Q9VQE3" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VQE3", "url": "https://www.uniprot.org/uniprotkb/Q9VQE3" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VQE3", "url": "https://www.uniprot.org/uniprotkb/Q9VQE3" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], 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"name": "uncharacterized protein, isoform C", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259969" }, "gene_names": [ { "name": "Dmel\\CG3104", "type": "recommended", "evidence": [ { "id": "Q9VQI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQI1" } ] }, { "name": "CG3104", "type": "synonym", "evidence": [ { "id": "NP_001259969", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259969" }, { "id": "Q9VQI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQI1" } ] }, { "name": "Dmel\\CG3104", "type": "synonym", "evidence": [ { "id": "NP_001259969", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259969" } ] }, { "name": "Dmel_CG3104", "type": "synonym", "evidence": [ { "id": "Q9VQI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQI1" } ] } ], "protein_names": [ { "name": "Ankyrin repeat domain-containing protein 29", "type": "recommended", "evidence": [ { "id": "Q9VQI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQI1/entry#names_and_taxonomy" } ] }, { "name": "CG3104-PC", "type": "synonym", "evidence": [ { "id": "NP_001259969", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259969" } ] }, { "name": "uncharacterized protein, isoform C", "type": "synonym", "evidence": [ { "id": "NP_001259969", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259969" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VQI1", "url": "https://www.uniprot.org/uniprotkb/Q9VQI1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG3104", "url": "https://www.uniprot.org/uniprotkb/Q9VQI1", "locus": { "chromosome": "2L", "start_pos": 2848989, "end_pos": 2855778, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0031473", "url": "https://www.ensemblgenomes.org/id/FBgn0031473" } ] } } ], "crossref": [ { "id": "FB:FBgn0031473", "url": "https://alliancegenome.org/gene/FB:FBgn0031473", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0031473", "url": "https://bgee.org/?page=gene&gene_id=FBgn0031473", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0031473", "url": "https://flybase.org/reports/FBgn0031473", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "33486", "url": "https://www.ncbi.nlm.nih.gov/gene/33486", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VQI1", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VQI1*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG3104", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3104", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CKDSYGT", "url": "https://omabrowser.org/oma/group/CKDSYGT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VQI1", "url": "https://www.orthodb.org/?gene=Q9VQI1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24188", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24188", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24188:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24188:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001259969", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259969", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VQI1", "url": "https://www.uniprot.org/uniprotkb/Q9VQI1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VQI1-1", "url": "https://www.uniprot.org/uniprotkb/Q9VQI1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLKKETPSDVQLHMAAMRGDEVALLRVLDSGKVHVDCKDEDGTTPLILAAAGGHTYCVMELLDQGADPNSRRLTGTTPLFFAAQGGHLDVVKILIKAGASVDTPSADGGTPLFVACQGGHVKIVRELLDCGANVNAHMKDRATPVFISAQNGHRTVLSLLIQAGAEIDIKRIDGATPLWIAAQMGQDHICKVLLQNGANVDTVRCDGATPLFKAAHKGHAAVITVLLKYRPNLGQLPNGESALHAAAMFGHMTVCKQLVAAGSDVLLKNHDGLTALQLAHQQKYTSICDYLQERIRTMVARSAKAMATSGVSSTVKTMSA", "length": 321, "header": "tr|Q9VQI1-1|Q9VQI1_DROME Isoform 1 of Ankyrin repeat domain-containing protein 29 OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG3104 PE=4 SV=2 CANONICAL=Q9VQI1-1" }, "isoforms": [ { "isoform_ac": "Q9VQI1-1", "url": "https://www.uniprot.org/uniprotkb/Q9VQI1/entry#Q9VQI1-1", "sequence": { "sequence": "MSLKKETPSDVQLHMAAMRGDEVALLRVLDSGKVHVDCKDEDGTTPLILAAAGGHTYCVMELLDQGADPNSRRLTGTTPLFFAAQGGHLDVVKILIKAGASVDTPSADGGTPLFVACQGGHVKIVRELLDCGANVNAHMKDRATPVFISAQNGHRTVLSLLIQAGAEIDIKRIDGATPLWIAAQMGQDHICKVLLQNGANVDTVRCDGATPLFKAAHKGHAAVITVLLKYRPNLGQLPNGESALHAAAMFGHMTVCKQLVAAGSDVLLKNHDGLTALQLAHQQKYTSICDYLQERIRTMVARSAKAMATSGVSSTVKTMSA", "length": 321, "header": "tr|Q9VQI1-1|Q9VQI1_DROME Isoform 1 of Ankyrin repeat domain-containing protein 29 OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG3104 PE=4 SV=2 CANONICAL=Q9VQI1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VQI1", "url": "https://www.uniprot.org/uniprotkb/Q9VQI1" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VQI1", "url": "https://www.uniprot.org/uniprotkb/Q9VQI1" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQI1", "url": "https://www.uniprot.org/uniprotkb/Q9VQI1" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQI1", "url": "https://www.uniprot.org/uniprotkb/Q9VQI1" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VQI1", "url": "https://www.uniprot.org/uniprotkb/Q9VQI1" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VQI1", "url": "https://www.uniprot.org/uniprotkb/Q9VQI1" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VQI1", "url": "https://www.uniprot.org/uniprotkb/Q9VQI1" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQI1", "url": "https://www.uniprot.org/uniprotkb/Q9VQI1" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQI1", "url": "https://www.uniprot.org/uniprotkb/Q9VQI1" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VQI1", "url": "https://www.uniprot.org/uniprotkb/Q9VQI1" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VQI1", "url": "https://www.uniprot.org/uniprotkb/Q9VQI1" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG3104", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3104", "resource": "KEGG Pathway" }, { "id": "R-DME-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8951664", "resource": "Reactome", "description": "Neddylation" }, { "id": "R-DME-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B790-1", "protein_name": "Ankyrin repeat domain 29", "gene_name": "ANKRD29", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MCRMSFKKETPLANAAFWAARRGNLTLLRLLLNSGRVDVDCRDSHGTTLLMVASYAGHIDCVKELVLQGADINLQRESGTTALFFAAQQGHNDVVRFLFEFGASTEFRTKDGGTALLAASQYGHMQVVETLLKHGANIHDQLYDGATALFLAAQGGYLDVIRLLLSSGAKVNQPRQDGTAPLWIASQMGHSEVVRVMLLRGADRDAARNDGTTALLKAANKGYNNVIEELLKFSPTLGILKNGTSALHAAVLSGNIKTVALLLEAGADPALRNKANELPAELTKNERILRLLRSKEGHRKS", "length": 301 }, "evidence": [ { "id": "Q9VQI1", "url": "https://omabrowser.org/oma/group/Q9VQI1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6A693-1", "protein_name": "Ankyrin repeat domain 29", "gene_name": "Ankrd29", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCRMSFKKETPLANAAFWAAKRGNLALLRLLLNSGRVDVDCRDSHGTTLLMVASYAGHIDCVRELVLQGADINLQRESGTTALFFAAQQGHNDVVRFLFGFGASTECRTKDGGTALLAASQYGHMPVVETLLKHGANIHDQLYDGATALFLAAQGGYLDVIRLLLSSGAKVNQPRQDGTAPLWIASQMGHSEVVRVMLLRGADRDAARNDGTTALLKAANKGYNDVIKELLKFSPTLGILKNGTSALHAAVLSGNVKTVALLLEAGADPALRNKANELPAELTKNEHILHLLRQKEGPGKNELGSVLDR", "length": 309 }, "evidence": [ { "id": "HGNC:27110", "url": "https://alliancegenome.org/gene/HGNC:27110#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050208-655", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-655#orthology", "database": "AGR" }, { "id": "RGD:1587260", "url": "https://alliancegenome.org/gene/RGD:1587260#orthology", "database": "AGR" }, { "id": "MGI:2687055", "url": "https://alliancegenome.org/gene/MGI:2687055#orthology", "database": "AGR" }, { "id": "FB:FBgn0031473", "url": "https://alliancegenome.org/gene/FB:FBgn0031473#orthology", "database": "AGR" }, { "id": "Q9VQI1", "url": "https://omabrowser.org/oma/group/Q9VQI1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0XNQ1-1", "protein_name": "Ankyrin repeat domain 29", "gene_name": "ANKRD29", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSFKKETPLANAAFWAARKGNLALLQLLLNSGRVDVDCKDSLGTTALMVASYYGHVDCVRELVLQGADINLQRESGATALFFAAQQGHNDVVKFLFEFGASTEFKNKELLWLLSCFVPAVPINVTGNLETHRSYRATDQDGGTALLAACQYGHTKVVETLLKHGANVHDQLYDGASAIFLAAQGGYLDVIRLLLSSGAKVNQPRQDGTAPLWIASQMGHSEVVRVMLLRGAERDAARDDGTTALLKAAIKGYNNVIEELLKFSPTLGLLKNGTSALHAAVLSGNVRTVALLLEAGADPCLRNKANELPAELTKNERILRLLRTKEKQRKS", "length": 330 }, "evidence": [ { "id": "Q9VQI1", "url": "https://omabrowser.org/oma/group/Q9VQI1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3YVV3-1", "protein_name": "Ankyrin repeat domain 29", "gene_name": "Ankrd29", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCRMSFKKETPLANAAFWAAKRGNLALLKLLLNSGRVDVDCRDSHGTTLLMVASYAGHIDCVRELVLQGADINLQRESGTTALFFAAQQGHNDVVRFLFGFGASTECRTKDGGTALLAASQYGHMPVVETLLKHGANIHDQLYDGATALFLAAQGGYLDVIRLLLSSGAKVNQPRQDGTAPLWIASQMGHSEVVRVMLLRGADRDAARNDGTTALLKAANKGYNDVIEELLKFSPTLGILKNGTSALHAAVLSGNVKTVALLLEAGADPALRNKANELPAELTKNERILHLLRQKEGPGKNELGSILDR", "length": 309 }, "evidence": [ { "id": "HGNC:27110", "url": "https://alliancegenome.org/gene/HGNC:27110#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050208-655", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-655#orthology", "database": "AGR" }, { "id": "RGD:1587260", "url": "https://alliancegenome.org/gene/RGD:1587260#orthology", "database": "AGR" }, { "id": "MGI:2687055", "url": "https://alliancegenome.org/gene/MGI:2687055#orthology", "database": "AGR" }, { "id": "FB:FBgn0031473", "url": "https://alliancegenome.org/gene/FB:FBgn0031473#orthology", "database": "AGR" }, { "id": "Q9VQI1", "url": "https://omabrowser.org/oma/group/Q9VQI1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q502M6-1", "protein_name": "Ankyrin repeat domain-containing protein 29", "gene_name": "ankrd29", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSFKKETPLANAVFWAARKGNLALLQLLLNSGRVDVDCKDAYGTTALMVASYSGHYECVRELIMQGADINLQRETGSTALFFASQQGHNEIVKLLFEFGASTEFQTKDGGTALCAACQFGHSRVVDTLLKNGANVHDQLNDGATALFLASQEGHVNLIRQLLSSGAKVNQPREDGTAPLWMAAQMGHSEVVKVLLLRGADRDADRKDGSTALFKAAHKGHCSVMEELLKFSPSLGILKNGSTALHAAVMGGSLKAVDLLLKANADPALPNTNNELPRDLTKSERILRVLRLPLMNGES", "length": 298 }, "evidence": [ { "id": "HGNC:27110", "url": "https://alliancegenome.org/gene/HGNC:27110#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050208-655", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-655#orthology", "database": "AGR" }, { "id": "RGD:1587260", "url": "https://alliancegenome.org/gene/RGD:1587260#orthology", "database": "AGR" }, { "id": "MGI:2687055", "url": "https://alliancegenome.org/gene/MGI:2687055#orthology", "database": "AGR" }, { "id": "FB:FBgn0031473", "url": "https://alliancegenome.org/gene/FB:FBgn0031473#orthology", "database": "AGR" }, { "id": "Q9VQI1", "url": "https://omabrowser.org/oma/group/Q9VQI1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8N6D5-1", "protein_name": "Ankyrin repeat domain-containing protein 29", "gene_name": "ANKRD29", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MCRMSFKKETPLANAAFWAARRGNLALLKLLLNSGRVDVDCRDSHGTTLLMVAAYAGHIDCVRELVLQGADINLQRESGTTALFFAAQQGHNDVVRFLFGFGASTEFRTKDGGTALLAASQYGHMQVVETLLKHGANIHDQLYDGATALFLAAQGGYLDVIRLLLASGAKVNQPRQDGTAPLWIASQMGHSEVVRVMLLRGADRDAARNDGTTALLKAANKGYNDVIKELLKFSPTLGILKNGTSALHAAVLSGNIKTVALLLEAGADPSLRNKANELPAELTKNERILRLLRSKEGPRKS", "length": 301 }, "evidence": [ { "id": "HGNC:27110", "url": "https://alliancegenome.org/gene/HGNC:27110#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050208-655", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-655#orthology", "database": "AGR" }, { "id": "RGD:1587260", "url": "https://alliancegenome.org/gene/RGD:1587260#orthology", "database": "AGR" }, { "id": "MGI:2687055", "url": "https://alliancegenome.org/gene/MGI:2687055#orthology", "database": "AGR" }, { "id": "FB:FBgn0031473", "url": "https://alliancegenome.org/gene/FB:FBgn0031473#orthology", "database": "AGR" }, { "id": "Q9VQI1", "url": "https://omabrowser.org/oma/group/Q9VQI1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VQI1", "url": "https://www.uniprot.org/uniprotkb/Q9VQI1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VQI1", "url": "https://www.uniprot.org/uniprotkb/Q9VQI1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cytoskeletal anchor activity", "id": "GO:0008093", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008093", "evidence": [ { "database": "UniProtKB", "id": "Q9VQI1", "url": "https://www.uniprot.org/uniprotkb/Q9VQI1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "Q9VQI1", "url": "https://www.uniprot.org/uniprotkb/Q9VQI1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VQJ8-1", "uniprot_ac": "Q9VQJ8", "uniprot_id": "Q9VQJ8_DROME", "mass": { "chemical_mass": 24738.0, "monoisotopic_mass": 24738.0 }, "refseq": { "ac": "NP_001285572", "name": "uncharacterized protein, isoform B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285572" }, "gene_names": [ { "name": "Dmel\\CG9643", "type": "recommended", "evidence": [ { "id": "Q9VQJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQJ8" } ] }, { "name": "CG9643", "type": "synonym", "evidence": [ { "id": "NP_001285572", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285572" }, { "id": "Q9VQJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQJ8" } ] }, { "name": "Dmel\\CG9643", "type": "synonym", "evidence": [ { "id": "NP_001285572", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285572" } ] }, { "name": "Dmel_CG9643", "type": "synonym", "evidence": [ { "id": "Q9VQJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQJ8" } ] }, { "name": "METTL10", "type": "synonym", "evidence": [ { "id": "NP_001285572", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285572" }, { "id": "Q9VQJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQJ8" } ] } ], "protein_names": [ { "name": "Protein-lysine N-methyltransferase CG9643", "type": "recommended", "evidence": [ { "id": "Q9VQJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQJ8/entry#names_and_taxonomy" } ] }, { "name": "2.1.1.-", "type": "synonym", "evidence": [ { "id": "Q9VQJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQJ8/entry#names_and_taxonomy" } ] }, { "name": "CG9643-PB", "type": "synonym", "evidence": [ { "id": "NP_001285572", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285572" } ] }, { "name": "uncharacterized protein, isoform B", "type": "synonym", "evidence": [ { "id": "NP_001285572", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285572" } ] } ], "function": [ { "annotation": "S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that methylates elongation factor 1-alpha.", "evidence": [ { "database": "UniProtKB", "id": "Q9VQJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VQJ8#function" }, { "database": "HAMAP", "id": "MF_03188", "url": "https://hamap.expasy.org/signature/MF_03188" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VQJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VQJ8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG9643", "url": "https://www.uniprot.org/uniprotkb/Q9VQJ8", "locus": { "chromosome": "2L", "start_pos": 2978411, "end_pos": 2979288, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0031485", "url": "https://www.ensemblgenomes.org/id/FBgn0031485" } ] } } ], "crossref": [ { "id": "FB:FBgn0031485", "url": "https://alliancegenome.org/gene/FB:FBgn0031485", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0031485", "url": "https://bgee.org/?page=gene&gene_id=FBgn0031485", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02440", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02440", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0031485", "url": "https://flybase.org/reports/FBgn0031485", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "33504", "url": "https://www.ncbi.nlm.nih.gov/gene/33504", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VQJ8", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VQJ8*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR025714", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025714", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026635", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026635", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG9643", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG9643", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTPSFQF", "url": "https://omabrowser.org/oma/group/PTPSFQF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VQJ8", "url": "https://www.orthodb.org/?gene=Q9VQJ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12843", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12843", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12843:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12843:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13847", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13847", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q9VQJ8", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q9VQJ8", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-DME-8876725", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8876725", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001285572", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285572", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VQJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VQJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VQJ8-1", "url": "https://www.uniprot.org/uniprotkb/Q9VQJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSELNGSELGTKEFWESSYNREIRNYKSHGDVGEIWFDESAQWRTIDWLLNEEKIDKEASRVLDLGCGNGMFLVGLANEGFTGDLTGVDYSPKAVELAQNIAEDNKLSITYKVADLTQPQNELGQFDVVHDKGTYDAVSLCPDNAKEKRALYLDTVEKLLRTADSLFVITSCNWTEDELVDSFAEKFVKYYTIPTPTFKFGGKVGNVVTSIVFKRKKE", "length": 219, "header": "tr|Q9VQJ8-1|Q9VQJ8_DROME Isoform 1 of Protein-lysine N-methyltransferase CG9643 OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG9643 PE=1 SV=1 CANONICAL=Q9VQJ8-1" }, "isoforms": [ { "isoform_ac": "Q9VQJ8-1", "url": "https://www.uniprot.org/uniprotkb/Q9VQJ8/entry#Q9VQJ8-1", "sequence": { "sequence": "MDSELNGSELGTKEFWESSYNREIRNYKSHGDVGEIWFDESAQWRTIDWLLNEEKIDKEASRVLDLGCGNGMFLVGLANEGFTGDLTGVDYSPKAVELAQNIAEDNKLSITYKVADLTQPQNELGQFDVVHDKGTYDAVSLCPDNAKEKRALYLDTVEKLLRTADSLFVITSCNWTEDELVDSFAEKFVKYYTIPTPTFKFGGKVGNVVTSIVFKRKKE", "length": 219, "header": "tr|Q9VQJ8-1|Q9VQJ8_DROME Isoform 1 of Protein-lysine N-methyltransferase CG9643 OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG9643 PE=1 SV=1 CANONICAL=Q9VQJ8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VQJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VQJ8" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VQJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VQJ8" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VQJ8" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VQJ8" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VQJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VQJ8" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VQJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VQJ8" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VQJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VQJ8" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VQJ8" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VQJ8" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VQJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VQJ8" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VQJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VQJ8" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG9643", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG9643", "resource": "KEGG Pathway" }, { "id": "R-DME-8876725", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8876725", "resource": "Reactome", "description": "Protein methylation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2QKF0-1", "protein_name": "EEF1A lysine methyltransferase 2", "gene_name": "Eef1akmt2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MNADADGHSGAAVPVQSREGSPVAADFVPSALGTREHWDAVYERELRTFQEYGDTGEIWFGEESMNRLIRWLQKHKIPSDASVLDIGTGNGVFLVELVKHGFSNITGIDYSPSAIKLSASILEKEGLSNINLKVEDFLSLSTKLSGFHVCVDKGTFDAISLNPDNAVEKRKQYVKSLSRVLEVKGFFLITSCNWTKAELLDVFSEGFELFEELPTPKFSFGGRSGNTVAALVFQKSETFLDKVS", "length": 244 }, "evidence": [ { "id": "Q9VQJ8", "url": "https://omabrowser.org/oma/group/Q9VQJ8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8I5ZLB6-1", "protein_name": "EEF1A lysine methyltransferase 2", "gene_name": "Eef1akmt2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNADAEGNSGAVVSAQSREGSPVADDFVPSALGTREHWDAVYERELKTFQDYGATGEIWFGEESMYRVIRWMQKHKIPLDASVLDIGTGNGVFLVELVDLNYHSVVGVVVNSLCMEILILANEEVKHGFSNITGIDYSPSAIKLSASILEKEGLSDVNLKVEDFLNLSTKLSGFHVCVDKGTYDAISLNPDNAVEKRKQYVMSLSRVLEVKGFFLITSCNWTKAELLDAFSEGFELFEELPTPKFSFGGRCGNTVAALVFQKRETSLDKVS", "length": 271 }, "evidence": [ { "id": "HGNC:33787", "url": "https://alliancegenome.org/gene/HGNC:33787#orthology", "database": "AGR" }, { "id": "Q9VQJ8", "url": "https://omabrowser.org/oma/group/Q9VQJ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ADU7-1", "protein_name": "EEF1A lysine methyltransferase 4", "gene_name": "Eef1akmt4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASPRTPVSPPELPERNLQYRQVQYWDQRYKDAADSGPYEWFGDFASFRALLEPELCPEDRILVLGCGNSALSYELFLGGFPNVTSVDYSPVVVAAMQVRYAHVPSLRWETMDIRALDFPSGSFDVVLEKGTLDALLAGEPDPWNVSSEGVHTVDQVLSEVSRVLVPGGRFISMTPAGPHFRIRHYAQPCYDWSLRHTTYSSGFHFHFYVMHKGRELTVSQLALGAQILSPPSPPAPPCFLQDSDNEDFLSAIQL", "length": 255 }, "evidence": [ { "id": "SGD:S000001326", "url": "https://alliancegenome.org/gene/SGD:S000001326#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P40516-1", "protein_name": "Protein-lysine N-methyltransferase EFM4", "gene_name": "EFM4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MQGTADLSTSKLGTKKYWDELYALELENFRRNPQDTGDCWFSDSDAEQKMIDFLVDNIGAYRISENASVVDLGTGNGHMLFELHQTEFQGKLVGIDYSEESVKLASNIAEATGVDNFISFQQADIFSGDWKPGKYDIVLDKGTLDAISLSGMKINGKLDVVDVYAGVVERILKKDGIFLITSCNFTQDELVKIIETDNLKMWKTIKYPVFQFGGVQGATICSVAFVKQN", "length": 229 }, "evidence": [ { "id": "MGI:1919346", "url": "https://alliancegenome.org/gene/MGI:1919346#orthology", "database": "AGR" }, { "id": "HGNC:33787", "url": "https://alliancegenome.org/gene/HGNC:33787#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050306-30", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050306-30#orthology", "database": "AGR" }, { "id": "FB:FBgn0031485", "url": "https://alliancegenome.org/gene/FB:FBgn0031485#orthology", "database": "AGR" }, { "id": "SGD:S000001326", "url": "https://alliancegenome.org/gene/SGD:S000001326#orthology", "database": "AGR" }, { "id": "Q9VQJ8", "url": "https://omabrowser.org/oma/group/Q9VQJ8/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54Y42-1", "protein_name": "Protein-lysine N-methyltransferase DDB_G0278427", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDSEDVVKVESCVLGTKGHWDSAYDRELDCFEETGDVGEIWFGKSCLKTMCKGVSQLSELNKETSKIIDLGCGNGMTLIELSKLGFKKLDGSDYSDKGIELAKRIMEQEGFNHINYFVDDITDSKIEQYVYDAVLDKGTFDAIALSEDRDRMKQLYKQHVEHILKPDGIFVITSCNYTENELKLYYTSPQFEFIKNIQYPVFSFGGSKGTTQTTLIFKKK", "length": 221 }, "evidence": [ { "id": "Q9VQJ8", "url": "https://omabrowser.org/oma/group/Q9VQJ8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5D013-1", "protein_name": "EEF1A lysine methyltransferase 2", "gene_name": "eef1akmt2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNSSVSTHGTGDCPVNCTKSEDFAPSKLGTKEYWDGAYKRELQTYKDIGDVGEIWFGEESMHRVIRWMEAQNISENAAILDIGTGNGMFLVELARHGFSNLTGIDYSKAALELTTNILVEEGLKNINIQVEDFLNPSTELKGFDVCIDKGTFDAISLNPEDREEAKKHYVTSLRAVMRPNGFFIITSCNWTKEQLLEIFKPGFELVRELPTPNFQFGGVTGNSVTALVFKQTD", "length": 233 }, "evidence": [ { "id": "MGI:1919346", "url": "https://alliancegenome.org/gene/MGI:1919346#orthology", "database": "AGR" }, { "id": "HGNC:33787", "url": "https://alliancegenome.org/gene/HGNC:33787#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050306-30", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050306-30#orthology", "database": "AGR" }, { "id": "FB:FBgn0031485", "url": "https://alliancegenome.org/gene/FB:FBgn0031485#orthology", "database": "AGR" }, { "id": "SGD:S000001326", "url": "https://alliancegenome.org/gene/SGD:S000001326#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5JPI9-2", "protein_name": "EEF1A lysine methyltransferase 2", "gene_name": "EEF1AKMT2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSGADGGGGAAVAARSDKGSPGEDGFVPSALGTREHWDAVYERELQTFREYGDTGEIWFGEESMNRLIRWMQKHKIPLDASVLDIGTGNGVFLVELAKFGFSNITGIDYSPSAIQLSGSIIEKEGLSNIKLKVEDFLNLSTQLSGFHICIDKGTFDAISLNPDNAIEKRKQYVKSLSRVLKVKGFFLITSCNWTKEELLNEFSEGFELLEELPTPKFSFGGRSGNSVAALVFQKM", "length": 236 }, "evidence": [ { "id": "MGI:1919346", "url": "https://alliancegenome.org/gene/MGI:1919346#orthology", "database": "AGR" }, { "id": "HGNC:33787", "url": "https://alliancegenome.org/gene/HGNC:33787#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050306-30", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050306-30#orthology", "database": "AGR" }, { "id": "FB:FBgn0031485", "url": "https://alliancegenome.org/gene/FB:FBgn0031485#orthology", "database": "AGR" }, { "id": "SGD:S000001326", "url": "https://alliancegenome.org/gene/SGD:S000001326#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9C9M1-1", "protein_name": "Protein-lysine N-methyltransferase At1g66680", "gene_name": "AR401", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAGIRLLPEEPETTPQQQARAAAAVTTTTTDSLASDDDRSIAADSWSIKSEYGSTLDDDQRHADAAEALSSANFRVSSDYSSDKEEPDADGGGQSMLGLQSYWDAAYSDELTNFREHGHAGEVWFGDDVMEIVTSWTKDLCVEISQRNMSVSENDVTTEVNDQADKYLSSWNVLDLGTGNGLLLHQLAKEGFSDLTGTDYSDGAVELAQHLSQRDGFPNIRFMVDDILDTKLEQQFKLVMDKGTLDAIGLHPDGPVKRVMYWDSVSKLVAPGGILVITSCNHTKDELVEEVENFNIRKSNLCRGDGNDANNVLSSGSEAASRIDQPPFEYLSHVRTYPTFMFSGSVGSRVATVAFLRK", "length": 358 }, "evidence": [ { "id": "Q9VQJ8", "url": "https://omabrowser.org/oma/group/Q9VQJ8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9D853-1", "protein_name": "EEF1A lysine methyltransferase 2", "gene_name": "Eef1akmt2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNADAEGHSGAVVPAQSPEGSSAADDFVPSALGTREHWDAVYERELRTFQEYGDTGEIWFGEESMNRLIRWMQKHKIPLDASVLDIGTGNGVFLVELVKHGFSNITGIDYSPSAIKLSASILEKEGLSNINLKVEDFLNPSTKLSGFHVCVDKGTYDAISLNPDNAIEKRKQYVMSLSRVLEVKGFFLITSCNWTKAELLDAFSEGFELFEELPTPKFSFGGRSGNTVAALVFQKRGTSLDKIS", "length": 244 }, "evidence": [ { "id": "MGI:1919346", "url": "https://alliancegenome.org/gene/MGI:1919346#orthology", "database": "AGR" }, { "id": "HGNC:33787", "url": "https://alliancegenome.org/gene/HGNC:33787#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050306-30", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050306-30#orthology", "database": "AGR" }, { "id": "FB:FBgn0031485", "url": "https://alliancegenome.org/gene/FB:FBgn0031485#orthology", "database": "AGR" }, { "id": "SGD:S000001326", "url": "https://alliancegenome.org/gene/SGD:S000001326#orthology", "database": "AGR" }, { "id": "Q9VQJ8", "url": "https://omabrowser.org/oma/group/Q9VQJ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VQJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VQJ8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "Q9VQJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VQJ8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-lysine N-methyltransferase activity", "id": "GO:0016279", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016279", "evidence": [ { "database": "UniProtKB", "id": "Q9VQJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VQJ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-DME-8932413", "name": "METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [ "R-DME-8932419" ], "enzyme_list": [ "Q9VQJ8-1" ], "evidence": [ { "id": "R-DME-8932413", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8932413" } ] } ], "reaction_participants": [ { "participant_id": "R-DME-8932419", "participant_name": "Me3K318-EEF1A1 [cytosol]", "crossref": [ { "id": "FBtr0085834", "database": "ENSEMBL", "url": "" }, { "id": "FBgn0000557", "database": "ENSEMBL", "url": "" }, { "id": "NP_524611.1", "database": "RefSeq", "url": "" }, { "id": "FBpp0085194", "database": "ENSEMBL", "url": "" }, { "id": "NP_996315.1", "database": "RefSeq", "url": "" }, { "id": "FBtr0085832", "database": "ENSEMBL", "url": "" }, { "id": "FBpp0089104", "database": "ENSEMBL", "url": "" }, { "id": "P05303", "database": "PRO", "url": "" }, { "id": "P05303", "database": "UniProt", "url": "" }, { "id": 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Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VQK7", "url": "https://www.uniprot.org/uniprotkb/Q9VQK7" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VQK7", "url": "https://www.uniprot.org/uniprotkb/Q9VQK7" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQK7", "url": "https://www.uniprot.org/uniprotkb/Q9VQK7" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQK7", "url": "https://www.uniprot.org/uniprotkb/Q9VQK7" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VQK7", "url": "https://www.uniprot.org/uniprotkb/Q9VQK7" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VQK7", "url": "https://www.uniprot.org/uniprotkb/Q9VQK7" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VQK7", "url": "https://www.uniprot.org/uniprotkb/Q9VQK7" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQK7", "url": "https://www.uniprot.org/uniprotkb/Q9VQK7" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQK7", "url": "https://www.uniprot.org/uniprotkb/Q9VQK7" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VQK7", "url": "https://www.uniprot.org/uniprotkb/Q9VQK7" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VQK7", "url": "https://www.uniprot.org/uniprotkb/Q9VQK7" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG3605", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3605", "resource": "KEGG Pathway" }, { "id": "R-DME-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" }, { "id": "R-DME-72165", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-72165", "resource": "Reactome", "description": "mRNA Splicing - Minor Pathway" }, { "id": "R-DME-9770562", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9770562", "resource": "Reactome", "description": "mRNA Polyadenylation" }, { "id": "R-DME-9943411", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9943411", "resource": "Reactome", "description": "CHD1 and CHD2 subfamily" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MC79-1", "protein_name": "Splicing factor 3B subunit 2 isoform X1", "gene_name": "Sf3b2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAAEHPEPPKGELQLPPPPPPGHYGAWAAQELQAKLAEIGAPIQGSREELVERLQTYTRQTGIVLNRPVLRGEDGDKAAPPPMSAQLSGIPMPPPPMGLPPLQPPPPPPPPPPGLGLGFPMAHPPNLGPPPPLRVGEPVALSEEERLKLAQQQAALLMQQEERAKQAAVLMEQERQQEIAKMGTAVPRPPQDMGQLGVRTPLGPRVAAPVGPVVPTPTVLPMGAPVPRPRGPPPPPGDENREMDDPSVGPKIPQALEKILQLKESRQEEMNSQQEEEEMETDTRSSLGQSASETEEDTVSISKKEKNRKRRNRKKKKKPQRVRAASSESSGDREKESARSRGSDSPAADVEIEYVTEEPEIYEPNFIFFKRIFEAFKLTDDVKKEKEKEPEKLDKMENSAVPKKKGFEEEHKDSDDDSSDDEQEKKPEAPKLSKKKLRRMNRFTVAELKQLVARPDVVEMHDVTAQDPKLLVHLKATRNSVPVPRHWCFKRKYLQGKRGIEKPPFELPDFIKRTGIQEMREALQEKEEQKTMKSKMREKVRPKMGKIDIDYQKLHDAFFKWQTKPKLTIHGDLYYEGKEFETRLKEKKPGDLSDELRISLGMPVGPNAHKVPPPWLIAMQRYGPPPSYPNLKIPGLNSPIPESCSFGYHAGGWGKPPVDETGKPLYGDVFGTNAAEFQTKTEEEEIDRTPWGELEPSDEESSEEEEEEESDEDKPDETGFITPADSGLITPGGFSSVPAGMETPELIELRKKKIEEAMDGSETPQLFTVLPEKRTATVGGAMMGSTHIYDMSTVMSRKGPAPELQGVEVALAPEELELDPMAMTQKYEEHVREQQAQVEKEDFSDMVAEHAAKQKQKKRKAQPQDSRGGSKKYKEFKF", "length": 878 }, "evidence": [ { "id": "Q9VQK7", "url": "https://omabrowser.org/oma/group/Q9VQK7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZMS1-1", "protein_name": "Splicing factor 3b, subunit 2", "gene_name": "Sf3b2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAEHPEPPKGELQLPPPPPPGHYGAWAAQELQAKLAEIGAPIQGSREELVERLQTYTRQTGIVLNRPVLRGEDGDKAAPPPMSAQLSGIPMPPPPLGLPPLQPPPPPPPPPPGLGLGFPMAHPPNLGPPPPLRVGEPVALSEEERLKLAQQQAALLMQQEERAKQAAVLMEQERQQEIAKMGTAVPRPPQDMGQLGVRTPLGPRVAAPVGPVVPTPTVLPMGAPVPRPRGPPPPPGDENREMDDPSVGPKIPQALEKILQLKESRQEEMNSQQEEEEMETDTRSSLGQSASETEEDTVSTSKKEKNRKRRNRKKKKKPQRVRAASSESSGDREKDSARSRGSDSPAADVEIEYVTEEPEIYEPNFIFFKRIFEAFKLTDDVKKEKEKEPEKLDKMENSAVPKKKGFEEEHKDSDDDSSDDEQEKKPEAPKLSKKKLRRMNRFTVAELKQLVARPDVVEMHDVTAQDPKLLVHLKATRNSVPVPRHWCFKRKYLQGKRGIEKPPFELPDFIKRTGIQEMREALQEKEEQKTMKSKMREKVRPKMGKIDIDYQKLHDAFFKWQTKPKLTIHGDLYYEGKEFETRLKEKKPGDLSDELRISLGMPVGPNAHKVPPPWLIAMQRYGPPPSYPNLKIPGLNSPIPESCSFGYHAGGWGKPPVDETGKPLYGDVFGTNAAEFQTKTEEEEIDRTPWGELEPSDEESSEEEEEEESDEDKPDETGFITPADSGLITPGGFSSVPAGMETPELIELRKKKIEEAMDGSETPQLFTVLPEKRTATVGGAMMGSTHIYDMSTVMSRKGPAPELQGVEVALAPEELELDPMAMTQKYEEHVREQQAQVEKEDFSDMVAEHAAKQKQKKRKAQPQDSRGGSKKYKEFKF", "length": 878 }, "evidence": [ { "id": "RGD:1307159", "url": "https://alliancegenome.org/gene/RGD:1307159#orthology", "database": "AGR" }, { "id": "MGI:2441856", "url": "https://alliancegenome.org/gene/MGI:2441856#orthology", "database": "AGR" }, { "id": "HGNC:10769", "url": "https://alliancegenome.org/gene/HGNC:10769#orthology", "database": "AGR" }, { "id": "FB:FBgn0031493", "url": "https://alliancegenome.org/gene/FB:FBgn0031493#orthology", "database": "AGR" }, { "id": "SGD:S000004853", "url": "https://alliancegenome.org/gene/SGD:S000004853#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RU38-1", "protein_name": "Splicing factor 3b subunit 2", "gene_name": "SF3B2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAEHPEPPKGELQLPPPPPPGHYGAWAAQELQAKLAEIGAPIQGSREELVERLQTYTRQTGIVLSRPVLRGEDGDKAAPPPMSAQLSGIPMPPPPMGLPPLQPPPPPPPPPPGLGLGFPMAVGPRPPNLGPPPPLRVGEPVALSEEERLKLAQQQAALLMQQEERAKQQGDHSLKEHELLEQQKRAAVLLEQERQQEIAKMGTPVPRPPQDLGQIGVRPPLGARVAAPVGPTPTVLPMGAPVPRPRGPPPPPGDENREMDDPSVGPKIPQALEKILQLKESRQEEMNSQQDEEEMETDTRSSLGPSASETEEDSVSVSKKEKNRKRRNRKKKKKPQRVRGLSSESSGDREKESSRSRGSDSPAADVEIEYVTEEPEIYEPNFIFFKRIFEAFKLTDDVKKEKEKEPEKLDKLENSAVPKKKGFEEEHKDSDDDSSDDEQEKKPEAPKLSKKKLRRMNRFTVAELKQLVARPDVVEMHDVTAQDPKLLVHLKATRNSVPVPRHWCFKRKYLQGKRGIEKPPFELPDFIKRTGIQEMREALQEKEEQKTMKSKMREKVRPKMGKIDIDYQKLHDAFFKWQTKPKLTIHGDLYYEGKEFETRLKEKKPGDLSDELRISLGMPVGPNAHKVPPPWLIAMQRYGPPPSYPNLKIPGLNSPIPESCSFGYHAGGWGKPPVDETGKPLYGDVFGTNAAEFQTKTEEEEIDRTPWGELEPSDEESSEEEEEEESDEDKPDETGFITPADSGLITPGGFSSVPAGMETPELIELRKKKIEEAMDGSETPQLFTVLPEKRTATVGGAMMGSTHIYDMSTVMSRKGPAPELQGVEVALAPEELELDPMAMTQKYEEHVREQQAQVEKEDFSDMVAEHAAKQKQKKRKAQPQDSRGGSKKYKEFKF", "length": 895 }, "evidence": [ { "id": "Q9VQK7", "url": "https://omabrowser.org/oma/group/Q9VQK7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q02554-1", "protein_name": "Cold sensitive U2 snRNA suppressor 1", "gene_name": "CUS1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MARTKSRKRSGNNQNKNASVVNNKAEIAAMIDARRLEQKKKGGVTNSKGKTNKVVDAKLEKEFKDVLQRFQVQENDTPKEITKDEKNNHVVIVEKNPVMNRKHTAEDELEDTPSDGIEEHLSARKRRKTEKPSLSQLKSQVPYPQIIEWYDCDARYPGLLASIKCTKNVIPVPSHWQSKKEYLSGRSLLGKRPFELPDIIKKTNIEQMRSTLPQSGLDGQDEKSLKEASRARVQPKMGALDLDYKKLHDVFFKIGANWKPDHLLCFGDVYYENRNLFEETNWKRMVDHKRPGRISQELRAIMNLPEGQLPPWCMKMKDIGLPTGYPDLKIAGLNWDITNLKGDVYGKIIPNHHSRSKKQGRNYFGALISFETPEFENSKEDTQANAENGRQDDKIDDEVEHKLDHFQEDISEVTSAEEKLERNEEESEKQLYTVLK", "length": 436 }, "evidence": [ { "id": "RGD:1307159", "url": "https://alliancegenome.org/gene/RGD:1307159#orthology", "database": "AGR" }, { "id": "MGI:2441856", "url": "https://alliancegenome.org/gene/MGI:2441856#orthology", "database": "AGR" }, { "id": "HGNC:10769", "url": "https://alliancegenome.org/gene/HGNC:10769#orthology", "database": "AGR" }, { "id": "FB:FBgn0031493", "url": "https://alliancegenome.org/gene/FB:FBgn0031493#orthology", "database": "AGR" }, { "id": "SGD:S000004853", "url": "https://alliancegenome.org/gene/SGD:S000004853#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q13435-1", "protein_name": "Splicing factor 3B subunit 2", "gene_name": "SF3B2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATEHPEPPKAELQLPPPPPPGHYGAWAAQELQAKLAEIGAPIQGNREELVERLQSYTRQTGIVLNRPVLRGEDGDKAAPPPMSAQLPGIPMPPPPLGLPPLQPPPPPPPPPPGLGLGFPMAHPPNLGPPPPLRVGEPVALSEEERLKLAQQQAALLMQQEERAKQQGDHSLKEHELLEQQKRAAVLLEQERQQEIAKMGTPVPRPPQDMGQIGVRTPLGPRVAAPVGPVGPTPTVLPMGAPVPRPRGPPPPPGDENREMDDPSVGPKIPQALEKILQLKESRQEEMNSQQEEEEMETDARSSLGQSASETEEDTVSVSKKEKNRKRRNRKKKKKPQRVRGVSSESSGDREKDSTRSRGSDSPAADVEIEYVTEEPEIYEPNFIFFKRIFEAFKLTDDVKKEKEKEPEKLDKLENSAAPKKKGFEEEHKDSDDDSSDDEQEKKPEAPKLSKKKLRRMNRFTVAELKQLVARPDVVEMHDVTAQDPKLLVHLKATRNSVPVPRHWCFKRKYLQGKRGIEKPPFELPDFIKRTGIQEMREALQEKEEQKTMKSKMREKVRPKMGKIDIDYQKLHDAFFKWQTKPKLTIHGDLYYEGKEFETRLKEKKPGDLSDELRISLGMPVGPNAHKVPPPWLIAMQRYGPPPSYPNLKIPGLNSPIPESCSFGYHAGGWGKPPVDETGKPLYGDVFGTNAAEFQTKTEEEEIDRTPWGELEPSDEESSEEEEEEESDEDKPDETGFITPADSGLITPGGFSSVPAGMETPELIELRKKKIEEAMDGSETPQLFTVLPEKRTATVGGAMMGSTHIYDMSTVMSRKGPAPELQGVEVALAPEELELDPMAMTQKYEEHVREQQAQVEKEDFSDMVAEHAAKQKQKKRKAQPQDSRGGSKKYKEFKF", "length": 895 }, "evidence": [ { "id": "RGD:1307159", "url": "https://alliancegenome.org/gene/RGD:1307159#orthology", "database": "AGR" }, { "id": "MGI:2441856", "url": "https://alliancegenome.org/gene/MGI:2441856#orthology", "database": "AGR" }, { "id": "HGNC:10769", "url": "https://alliancegenome.org/gene/HGNC:10769#orthology", "database": "AGR" }, { "id": "FB:FBgn0031493", "url": "https://alliancegenome.org/gene/FB:FBgn0031493#orthology", "database": "AGR" }, { "id": "SGD:S000004853", "url": "https://alliancegenome.org/gene/SGD:S000004853#orthology", "database": "AGR" }, { "id": "Q9VQK7", "url": "https://omabrowser.org/oma/group/Q9VQK7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q1ZXF6-1", "protein_name": "PSP proline-rich domain-containing protein", "gene_name": "sf3b2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDTTLTETIQNNNNINKSINNKKKLKHQKKKEQKKKQKQQKKEENIFQQTNNNNIKEEIKLENNDENNDENNNNNDDDKITAPIDGFSIDENDPSFELFSKLVKHFDNPYEDPKEIERKEQEEQEEKERKEREEEEERKKKEDNEDDDDDNNDDDDNNNDNEDEDSKKLSNKERKRQRKLHLPILKQLVDRPDVVELHDVNSPNPGYLIAMKSYRNTIPVPAHWCQKKKYLQGKRGFVKPPFELPSFIAATGITKIREAILEKEKEMKSKQKQRERVQPKIRKMGIDYEVLRDAFFVHQTKPNLSIQGDLYYEGKEFEVNLKNKKPGVLSDELKRALGMIEGYPPPWLIYMQTYGPPPSYPNLKIPGVNSPIPEGAQYGFHPGGWGRPVLNEFGKPLYENVNNNNNNINNNGDQQQQQQQSHPTREYWGELLPESEDFQEEEEQQEQQGTEEDELQQHQLEDDESIGDGISSVPSGLETPDIVNIKKSRYDQQQQQQQQQPRELYQVIEQQNKNSSSGGLMESAHRYNIPSVIKQQQQQQQQQNSSRVDVIKSQRSAPVEITLNPSEVENGQEIDEELLKKKYEQATQALQKQRPKEDISDIIEEQNKKRKNQLQKEEKQKKFKF", "length": 625 }, "evidence": [ { "id": "Q9VQK7", "url": "https://omabrowser.org/oma/group/Q9VQK7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q3UJB0-1", "protein_name": "Splicing factor 3B subunit 2", "gene_name": "Sf3b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAEHPEPPKGELQLPPPPPPGHYGAWAAQELQARLAEIGAPIQGSREELVERLQTYTRQTGIVLNRPVLRGEDGDKAAPPPMSAQLSGIPMPPPPMGLPPLQPPPPPPPPPPGLGLGFPMAHPPNLGPPPPLRVGEPVALSEEERLKLAQQQAALLMQQEERAKQAAVLMEQERQQEIAKMGTAVPRPPQDMGQLGVRTPLGPRVAAPVGPVVPTPTVLPMGAPVPRPRGPPPPPGDENREMDDPSVGPKIPQALEKILQLKESRQEEMNSQQEEEEMETDTRSSLGQSASETEEDTVSISKKEKNRKRRNRKKKKKPQRVRAASSESSGDREKDSGRSRGSDPPAADVEIEYVTEEPEIYEPNFIFFKRIFEAFKLTDDVKKEKEKEPEKLDKMESSAVPKKKGFEEEHKDSDDDSSDDEQEKKPEAPKLSKKKLRRMNRFTVAELKQLVARPDVVEMHDVTAQDPKLLVHLKATRNSVPVPRHWCFKRKYLQGKRGIEKPPFELPDFIKRTGIQEMREALQEKEEQKTMKSKMREKVRPKMGKIDIDYQKLHDAFFKWQTKPKLTIHGDLYYEGKEFETRLKEKKPGDLSDELRISLGMPVGPNAHKVPPPWLIAMQRYGPPPSYPNLKIPGLNSPIPESCSFGYHAGGWGKPPVDETGKPLYGDVFGTNAAEFQTKTEEEEIDRTPWGELEPSDEESSEEEEEEESDEDKPDETGFITPADSGLITPGGFSSVPAGMETPELIELRKKKIEEAMDGSETPQLFTVLPEKRTATVGGAMMGSTHIYDMSTVMSRKGPAPELQGVEVALAPEELELDPMAMTQKYEEHVREQQAQVEKEDFSDMVAEHAAKQKQKKRKAQPQDSRGGSKKYKEFKF", "length": 878 }, "evidence": [ { "id": "RGD:1307159", "url": "https://alliancegenome.org/gene/RGD:1307159#orthology", "database": "AGR" }, { "id": "MGI:2441856", "url": "https://alliancegenome.org/gene/MGI:2441856#orthology", "database": "AGR" }, { "id": "HGNC:10769", "url": "https://alliancegenome.org/gene/HGNC:10769#orthology", "database": "AGR" }, { "id": "FB:FBgn0031493", "url": "https://alliancegenome.org/gene/FB:FBgn0031493#orthology", "database": "AGR" }, { "id": "SGD:S000004853", "url": "https://alliancegenome.org/gene/SGD:S000004853#orthology", "database": "AGR" }, { "id": "Q9VQK7", "url": "https://omabrowser.org/oma/group/Q9VQK7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q9VQK7", "url": "https://www.uniprot.org/uniprotkb/Q9VQK7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "Q9VQK7", "url": "https://www.uniprot.org/uniprotkb/Q9VQK7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "Q9VQK7", "url": "https://www.uniprot.org/uniprotkb/Q9VQK7" } ], "pmid": "" }, { "name": "U2 snRNP", "id": "GO:0005686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005686", "evidence": [ { "database": "UniProtKB", "id": "Q9VQK7", "url": "https://www.uniprot.org/uniprotkb/Q9VQK7" } ], "pmid": "" }, { "name": "precatalytic spliceosome", "id": "GO:0071011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071011", "evidence": [ { "database": "UniProtKB", "id": "Q9VQK7", "url": "https://www.uniprot.org/uniprotkb/Q9VQK7" } ], "pmid": "" }, { "name": "U12-type spliceosomal complex", "id": "GO:0005689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005689", "evidence": [ { "database": "UniProtKB", "id": "Q9VQK7", "url": "https://www.uniprot.org/uniprotkb/Q9VQK7" } ], "pmid": "" }, { "name": "U2-type spliceosomal complex", "id": "GO:0005684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005684", "evidence": [ { "database": "UniProtKB", "id": "Q9VQK7", "url": "https://www.uniprot.org/uniprotkb/Q9VQK7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 115, "end_pos": 117, "annotation": "n_glycosylation_sequon" }, { "start_pos": 218, "end_pos": 220, "annotation": "n_glycosylation_sequon" }, { "start_pos": 628, "end_pos": 630, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VQK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQK7" }, { "id": "SM00581", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00581" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PSP proline-rich", "eco_id": "ECO_0000259", "start_pos": 451, "end_pos": 509, "start_aa": "Leu", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 115, "end_pos": 117 }, { "start_pos": 218, "end_pos": 220 }, { "start_pos": 628, "end_pos": 630 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VQQ3-1", "uniprot_ac": "Q9VQQ3", "uniprot_id": "Q9VQQ3_DROME", "mass": { "chemical_mass": 15791.0, "monoisotopic_mass": 15791.0 }, "refseq": { "ac": "NP_608774", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608774" }, "gene_names": [ { "name": "Dmel\\CG8840", "type": "recommended", "evidence": [ { "id": "Q9VQQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ3" } ] }, { "name": "CG8840", "type": "synonym", "evidence": [ { "id": "NP_608774", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608774" }, { "id": "Q9VQQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ3" } ] }, { "name": "Dmel\\CG8840", "type": "synonym", "evidence": [ { "id": "NP_608774", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608774" } ] }, { "name": "Dmel_CG8840", "type": "synonym", "evidence": [ { "id": "Q9VQQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ3" } ] } ], "protein_names": [ { "name": "BLOC-1-related complex subunit 7", "type": "recommended", "evidence": [ { "id": "Q9VQQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ3/entry#names_and_taxonomy" } ] }, { "name": "CG8840-PA", "type": "synonym", "evidence": [ { "id": "NP_608774", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608774" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_608774", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608774" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ3", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG8840", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ3", "locus": { "chromosome": "2L", "start_pos": 3411199, "end_pos": 3410560, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0031531", "url": "https://www.ensemblgenomes.org/id/FBgn0031531" } ] } } ], "crossref": [ { "id": "FB:FBgn0031531", "url": "https://alliancegenome.org/gene/FB:FBgn0031531", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0031531", "url": "https://bgee.org/?page=gene&gene_id=FBgn0031531", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0031531", "url": "https://flybase.org/reports/FBgn0031531", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "33557", "url": "https://www.ncbi.nlm.nih.gov/gene/33557", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VQQ3", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VQQ3*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "dme:Dmel_CG8840", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG8840", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VKDIDYW", "url": "https://omabrowser.org/oma/group/VKDIDYW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VQQ3", "url": "https://www.orthodb.org/?gene=Q9VQQ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "NP_608774", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608774", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VQQ3", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VQQ3-1", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASMELTLKSDYSADSVIDDIISKSLASQAVPRTHKRSTRVSFRSLAKVIMTLIGNLKKASSFHEVKDIDYWRNLAESRLEVNNRYGRFIEAQQRRIYTLETRLHNLVNLARETQKMLAEIGAEKRACEELGHGEHAD", "length": 138, "header": "tr|Q9VQQ3-1|Q9VQQ3_DROME Isoform 1 of BLOC-1-related complex subunit 7 OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG8840 PE=4 SV=2 CANONICAL=Q9VQQ3-1" }, "isoforms": [ { "isoform_ac": "Q9VQQ3-1", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ3/entry#Q9VQQ3-1", "sequence": { "sequence": "MASMELTLKSDYSADSVIDDIISKSLASQAVPRTHKRSTRVSFRSLAKVIMTLIGNLKKASSFHEVKDIDYWRNLAESRLEVNNRYGRFIEAQQRRIYTLETRLHNLVNLARETQKMLAEIGAEKRACEELGHGEHAD", "length": 138, "header": "tr|Q9VQQ3-1|Q9VQQ3_DROME Isoform 1 of BLOC-1-related complex subunit 7 OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG8840 PE=4 SV=2 CANONICAL=Q9VQQ3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ3", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ3" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ3", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ3" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ3", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ3" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ3", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ3" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ3", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ3" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. 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F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ3", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ3" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ3", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ3" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"description": "" }, { "id": "MIM:278000", "resource": "MIM", "url": "https://www.omim.org/entry/278000", "name": "Cholesteryl ester storage disease", "description": "Cholesteryl ester storage disease" } ], "unlinked_id_list": [], "evidence": [ { "id": "0080217", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080217" } ] }, { "disease_id": "DOID:14497", "recommended_name": { "id": "DOID:14497", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14497", "name": "Wolman disease", "description": "A lysosomal acid lipase deficiency characterized by infantile onset of rapidly progressive accumulation of cholesteryl esters and triglycerides throughout the body, resulting in hepatosplenomegaly, severe malnutrition, jaundice, vomiting, diarrhea, steatorrhea. Death usually occurs within the first year of life." }, "synonyms": [ { "id": "DOID:14497", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14497", "name": "Acid esterase deficiency", "description": "" }, { "id": "DOID:14497", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14497", "name": "Acid lipase deficiency", "description": "" }, { "id": "DOID:14497", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14497", "name": "Wolman xanthomatosis", "description": "" }, { "id": "DOID:14497", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14497", "name": "Wolman's disease", "description": "" }, { "id": "DOID:14497", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14497", "name": "Wolman's or triglyceride storage type III disease", "description": "" }, { "id": "DOID:14497", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14497", "name": "Xanthomatosis, familial", "description": "" }, { "id": "DOID:14497", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14497", "name": "acute infantile lysosomal acid lipase deficiency", "description": "" }, { "id": "DOID:14497", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14497", "name": "complete LAL deficiency", "description": "" }, { "id": "DOID:14497", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14497", "name": "complete LIPA deficiency", "description": "" }, { "id": "DOID:14497", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14497", "name": "complete cholesterol ester hydrolase deficiency", "description": "" }, { "id": "DOID:14497", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14497", "name": "complete lysosomal acid lipase deficiency", "description": "" }, { "id": "MONDO:0019148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019148", "name": "Wolman disease", "description": "Wolman disease represents the most severe manifestation of lysosomal acid lipase deficiency. 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PE=3 SV=1 CANONICAL=Q9VQQ5-1" }, "isoforms": [ { "isoform_ac": "Q9VQQ5-1", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ5/entry#Q9VQQ5-1", "sequence": { "sequence": "MLAKVLTILAIVASAGAADDFDPFIDIPFKRLKTSAERIAEHGYPAESHFVETPDGYVLNVFRIPHSPKLNSNGNEGESEASRPVVLIMHGLFSCSDCFLLNGPEDALPYNYADAGYDVWLGNARGNIYSRNNTRLNVKHPYFWKFSWHEIGSIDLPATIDYILAETGQQSLHYVGHSQGCTSFFVMGSYRPEYNAKIKTAHMLAPPVYMGNSTEGLIVSTAPLFGHHGIGSTLLENQVLLPQNAFIQRVLDTTCSNQPIMLSYCKTLAILWGGPEIGNLNQTLLPQIAETHPAGVSSNQAIHYIQSYASNDFRLYDWGSKRNLEYYGVSEPPAYDLTKITSELYLYYGLADGSANKQDISRLPDLLPNLALLHEVPDSTWGHLDFIFATEVKRVINDLVLDYSKAYDARETNNEI", "length": 416, "header": "tr|Q9VQQ5-1|Q9VQQ5_DROME Isoform 1 of Lipase OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG2772 PE=3 SV=1 CANONICAL=Q9VQQ5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ5" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ5" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ5" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ5" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ5" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ5" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ5" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ5" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ5" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ5" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VQQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VQQ5" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG2772", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG2772", "resource": "KEGG Pathway" }, { "id": "R-DME-192456", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-192456", "resource": "Reactome", "description": "Digestion of dietary lipid" }, { "id": "R-DME-6809371", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6809371", "resource": "Reactome", "description": "Formation of the cornified envelope" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K430-1", "protein_name": "Lipase", "gene_name": "Lipn", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPVMWLFLTTACLIRGTLSAGGFFENTVNPEVWMNASEIITYNGYPSEEYDVTTADGYILAINRIPHGRGQTGHAGPRPVVYMQHALFADNAYWLENFPNGSLGFLLADAGYDVWMGNSRGNTWSRRHKTLSVNEEKFWAFSFDEMAKYDLPGIIDFIVNKTGQEKLYFIGHSLGTTIGFIAFSTMPELAQRIKMNFALGPVISFKYPTSIFTSFFLLPRSMIKLMFGTKGFFLEDKNAKMSYVTVCNKKLLRPMCSEFMSLWAGFNKKNMNMSRLDVYMSHAPTGSSIQNILHIKQLYQSDEFRAYDWGSEAENMNHYNQSRPPLYDLTAMKVPTAIWAGGHDVLVTPQDVARILPQITNLRYFKQFPEWNHFDFVWGLDAPQRLYSKIIGLMKEYR", "length": 398 }, "evidence": [ { "id": "MGI:1917416", "url": "https://alliancegenome.org/gene/MGI:1917416#orthology", "database": "AGR" }, { "id": "FB:FBgn0031533", "url": "https://alliancegenome.org/gene/FB:FBgn0031533#orthology", "database": "AGR" }, { "id": "RGD:1560354", "url": "https://alliancegenome.org/gene/RGD:1560354#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A494BBH0-1", "protein_name": "Lipase", "gene_name": "Gm8978", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLWLLRTMCLIHVLGKIFCLIGQNKNPESNMNVSEIIKHWEYPSEEYEVVTDDGYILPINRIPHGKNNANSTAPKMVVFCLHGLFSTAGIWVSNPPDNSLAFILADAGYDVWLGNNRGSTRAKKHVTLNTDSKEFWAFSYDEMIKYDLPAIIKFILEKTGQKQIYYTGHSQGTLIALGAFATNQELAEKIKLSILIAPVHTVKYVKGAGRLPAYFTPTAFKIVFGEKEFFPTKVFSRLSQHVCDIKLVDAGCATVLGSLTGYSPEQFNTSRIDVYITHSLGESSIQILIHYGQAIRSGVFQAYDWGSPSLNMQHYNQTTPPVYNVEDMKVPTAMFSGLKDFLSNPEDVANLVPKISNLTYHKIISDFSHLDFIMGLNARKEVSEEILTILRKYDGDIQI", "length": 399 }, "evidence": [ { "id": "MGI:3647649", "url": "https://alliancegenome.org/gene/MGI:3647649#orthology", "database": "AGR" }, { "id": "FB:FBgn0031533", "url": "https://alliancegenome.org/gene/FB:FBgn0031533#orthology", "database": "AGR" }, { "id": "RGD:1565682", "url": "https://alliancegenome.org/gene/RGD:1565682#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YY49-1", "protein_name": "Lipase", "gene_name": "Lipo2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLWLLRTMCLIQVLGKIFCLFGPKKNPEAHMNVSEIIKHWDYPSEEYEVVTDDGYILPINRIPHGKNNAKSPAPKMVVFCQHGLLATPGAWVSNPPVNSLAFILADAGYDVWMGSSRGSTWAKKHVTLNPDSKEFWDFSFDQMIKYDLPATINFILDKTGQKQIYYIGHSQGTLLAIGAFATNQKLAEKIKLNILLAPIYSVQHSKGISHLASYLTPTTIKLLFGEKEFLPTVVFSEVGACVCNINFFTAICAAIMGSMGGYSPEELNKSRLDVYVKLNLAGTSVKVLIHYNQVGRSGILQAYDWGSPSLNMRHYNQTTPPVYNVEDMKVPTAMFTGLKDFLSDPEDVEILKPKIHNLTYLKTIPDFSHFDFIWGLNTREEVSEEILTILRKYDGDYI", "length": 398 }, "evidence": [ { "id": "MGI:3644466", "url": "https://alliancegenome.org/gene/MGI:3644466#orthology", "database": "AGR" }, { "id": "FB:FBgn0031533", "url": "https://alliancegenome.org/gene/FB:FBgn0031533#orthology", "database": "AGR" }, { "id": "RGD:2321667", "url": "https://alliancegenome.org/gene/RGD:2321667#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZUQ1-1", "protein_name": "Lipase", "gene_name": "Lipo1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWWLLRTMCLIHVFGKIFCLLEPNKNPESHMNVSEIIKYWNYPSLEYEVVTDDGYILPINRIPHGKNNANSSAPKMVVFCQHGLFSTPGVWVANPPDNSLAFILAEAGYDVWLGNSRGSTWAKKHVTLSPDSEEFWAFSFDQMIAYDLPATINFILNTTGQEQIYYIGHSLGTLIALGAFSTNQELAEKIKLNILIAPVRTVKYVKGFGRLLAYFSPEAFKLVFGKKEFLPTVVFSEYSKYVCNIKLVDAGCAGVLGSLTGFSEDQLNTSRIDVYITHSLAGTSTQILIHAGQAIRSGEFQAYDWGSPSLNMQHYNQTTPPLYSVENMKVPTVMFTGLKDFLADPKDVANLVPKIFNLIYHKTIPEFSHLDFIVGLNAKTEVSDEILTILGEYDSSVL", "length": 398 }, "evidence": [ { "id": "MGI:3647308", "url": "https://alliancegenome.org/gene/MGI:3647308#orthology", "database": "AGR" }, { "id": "MGI:3647649", "url": "https://alliancegenome.org/gene/MGI:3647649#orthology", "database": "AGR" }, { "id": "FB:FBgn0031533", "url": "https://alliancegenome.org/gene/FB:FBgn0031533#orthology", "database": "AGR" }, { "id": "RGD:1565682", "url": "https://alliancegenome.org/gene/RGD:1565682#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A9L7-1", "protein_name": "Lipase", "gene_name": "Lipk", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWWLLATCCMFLPGPIYGHMQESITNPEANMNISEIISYWGYPYERHDVVTEDGYILGTYRIPHGKGCSRKAVPKAVVYLQHGLIASASNWICNLPNNSLAFLLADSGYDVWLGNSRGNTWSRKHLRLSPKSPEYWAFSLDEMAKYDLPATINLILEKSGQKQLFYVGHSQGTTIAFIAFSTNPELAKKIRMFFALAPVVTVKYTQSPMKKLTTLSRKAVKILFGDKMFSTHTWLEQFIATKVCNRKLFRQLCSNFLFSLSGFDPQNLNMSRLDVYMAQSPAGTSVQNMLHWAQAVNSGQLQAFDWGNPDQNMMHFNQLTPPVYNISKMRVPTAMWSGGRDVVADEKDTKNLLPKVANLIYYKEIPHYNHMDFYLGQDAPQEVYRDLITMMEESLQN", "length": 397 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" }, { "id": "MGI:2679259", "url": "https://alliancegenome.org/gene/MGI:2679259#orthology", "database": "AGR" }, { "id": "FB:FBgn0031533", "url": "https://alliancegenome.org/gene/FB:FBgn0031533#orthology", "database": "AGR" }, { "id": "RGD:1309724", "url": "https://alliancegenome.org/gene/RGD:1309724#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AA61-1", "protein_name": "Lipase", "gene_name": "Lipm", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEILSRAWSVSHRVEIWLLILVAYLLQRNVNSGHMPTKAADPEAFMNVSEIIKHKGYPSEEYEVATEDGYILSVNRIPRGQTQLKKEGSRPVVLLQHGLLGDASNWISNLPNNSLGFILADAGFDVWMGNSRGNTWSRKHKTLSIDQDEFWAFSYDEMARFDLPAVINFILQKTGQKKIYYVGYSQGTTMGFIAFSTMPELAHKIKMYFALAPIATVKHAKSPGTKFLLLPDMMIKGLFGRQEFLYQTRFFRQLFIYLCGQMILDQICSNIILLLGGFNTNNMNMSRANVYVAHTPAGTSVQNILHWSQAVNSGELRAFDWGSETKNREKSNQPTPIRYKVRDMMVPTAMWTGGQDWLSNPDDVKTLLSEVTNLIYHKNIPEWAHVDFIWGLDAPHRVYNEIIHLMKQESSLPQGTCRVKL", "length": 422 }, "evidence": [ { "id": "MGI:1926003", "url": "https://alliancegenome.org/gene/MGI:1926003#orthology", "database": "AGR" }, { "id": "FB:FBgn0031533", "url": "https://alliancegenome.org/gene/FB:FBgn0031533#orthology", "database": "AGR" }, { "id": "RGD:1304912", "url": "https://alliancegenome.org/gene/RGD:1304912#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E2QCS7-1", "protein_name": "AB hydrolase-1 domain-containing protein", "gene_name": "Dmel\\CG17097", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTIVLNLPVCVLFLLGTLVPSNSQKWIPYANPLDEQSQLQEIGLSDQNPDNFEQSQSQSQDQIVAQILPSDASLSGGQPPNNIIQLVDEGMDRPLLLQPQNRPIETVDQSQNLIQRKLQSQSQAQALAESQAQSQAQSQAQSQAQSQAQLQAQLQAQSQAQSQAQSQAQLQSQLQSQIQSQLQSDLQSQSQLQAQLQSQLDALKQQSGLQKLAFGQLKPQVSDQPILILDSIPKPRPQFVLLPPQNGPVQQDPNLRYVIIPSPPKRKRRISPDSSTIPKVYILTPDKQIKSNTSINIDQLLKLYKYKTDKERKIAELKRQIKELKKQNLFNLVPALQLRPAIPAIELQLPVESQSEIQSQIASQQSGSLSQLQSQQNSKSSGSQSNAQSSGSQSQYQLQSDSQSSGSQSQLQSQSNPQSSGTQSQLQSQNRRLQSQLQSQNRGSQSQLQSQINPQSSGSQSQLQSQINPQSSGSQSQLQSQNRGSQSQLQSQNRGSQSQLQSEISPQSSGSQSQLQSQIDLHSDASQSQLQSQLGYDSTGSQSQLQSQLDSQLSGAQSQLQSQFNSQSSESQSQLQSQAKFRSLGAQSQSQSQLNSQSLGSQSQSQSQLNSQSSGSQSQSQSQLNSQSSGSQSQSQSQLNSQSLGSQSQSQLQIRSQLGTQTLESQSPSEVLLHIQGPSTYQDNLAESNIQTQKNRINVVTPEYKVFKTPNYLTQEDILDNTKLTTVDLIEKYGYPSETNYVTSEDGYRLCLHRIPRPGAEPVLLVHGLMASSASWVELGPKDGLAYILYRKGYDVWMLNTRGNIYSRENLNRRLKPNKYWDFSFHEIGKFDVPAAIDHILIHTHKPKIQYIGHSQGSTVFFVMCSERPNYAHKVNLMQALSPTVYLQENRSPVLKFLGMFKGKYSMLLNLLGGYEISAKTKLIQQFRQHICSGSELGSSICAIFDFVLCGFDWKSFNTTLTPIVAAHASQGASAKQIYHYAQLQGDLNFQRFDHGAVLNRVRYESSEPPAYNLSQTTSKVVLHHGEGDWLGSTSDVIRLQERLPNLVESRKVNFEGFSHFDFTLSKDVRPLLYSHVLRHLSTSLSG", "length": 1087 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "F6RR30-1", "protein_name": "Lipase", "gene_name": "Lipo4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLWLLRTMCLIHLLGKLFCSFGTKKNPEAHMNVSQIIKHWEYPSEEYEVVTDDGYILPINRIPHGKNNANSSAPKMVVFCQHGLLATPGAWVSNLPDNSLAFILADAGYDVWMGSSRGSTWAKKHVTLNTDSKEFWDFSFDQMIKYDLPATINFILDKTGQKQIYYIGHSQGTLIAIGAFATNQKLAEKIKLNILLAPIYSVQHSKGIARLTSYLTPTTIKVLFGEKEFLPTVVSSEVGAYVCDINLVTAGCAAMIGSMGGYSPEQLNMSRLDVYVKLNLAGTSVKILIHYNQIRRSGILQAYDWGSSSLNMQHYNQTTPPVYNVEDMKVPTAMFTGLKDFLSDPEDVEILKPKIHNLTYLKTIPDFSHFDFIWGLNAREEVSEEILTILRKYDGDYI", "length": 398 }, "evidence": [ { "id": "MGI:3779637", "url": "https://alliancegenome.org/gene/MGI:3779637#orthology", "database": "AGR" }, { "id": "FB:FBgn0031533", "url": "https://alliancegenome.org/gene/FB:FBgn0031533#orthology", "database": "AGR" }, { "id": "RGD:2321667", "url": "https://alliancegenome.org/gene/RGD:2321667#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6WYC8-1", "protein_name": "Lipase", "gene_name": "Lipo1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLWLLRTMCLIHVLGKIFCLIGPNKNPESNMNVSQIIKHWEYPSEEYEVVTDDGYILPINRIPHGKNNANSSAPKMVVFCLPGLFSTAGVWVSNPPDNSLAFILADAGYDVWLGNNRGSTWAKKHVTLNPDSKEFWAFSYDEMIKYDLPAIINFILEKTGQKQIYYAGHSQGTLIALGAFATNQELAEKIKLSILIAPIHTVKYVKGSGRLPAYFTPTAFKIVFGEKEFFPTKVFSRLSQHVCDIKLVDAGCATVLGSLTGYSPEQLNTSRVDVYITHSLAESSVQILIHYGQAIRSGVFQAYDWGSPSLNMQHYNQTTPPVYNVEDMKVPTAMFSGLKDFLSNPEDVANLVPKISNLTYHKIISDFSHLDFITGLNAREEVSEEILTILRKYDGDIQI", "length": 399 }, "evidence": [ { "id": "MGI:3647308", "url": "https://alliancegenome.org/gene/MGI:3647308#orthology", "database": "AGR" }, { "id": "FB:FBgn0031533", "url": "https://alliancegenome.org/gene/FB:FBgn0031533#orthology", "database": "AGR" }, { "id": "RGD:1565682", "url": "https://alliancegenome.org/gene/RGD:1565682#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0R7L1-1", "protein_name": "Lipase", "gene_name": "Lipj", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWWLLRTLCFVHVIGSIFCFLNAKPKNPEANMNVSQIISYWGYESEEHEVMTEDGYILLIFRIPHGKNENKSSHNTRRPVVYLHHGLTVSADYWILDPPSNCLAFLLADAGFEVWLGNSRGTNNARKHVRLDPDSKEFWDFSFNEQIEYDLPAIIYFILNETRQTQIYYIGHSQGVYLAYAAFATNPQLAQKIKINFALGPVVITKYLTGVFRTIAYIHPTVIKTMFGEKDIFSKSNANDILRFLCHREQIATACTSLLIVLFGYNPGNLNESRIDVYSEHIPAGTSVRSILHFSQGIRSGLFQAYDWGSESLNVLHYNQSTPPIYNIEDMKVRTAMWSGERDLLGDPKDVKNLAAKTPNLIYHKKIPHYNHMDFILGKDAVVQVYRKIIEFINRDQSE", "length": 399 }, "evidence": [ { "id": "MGI:3779637", "url": "https://alliancegenome.org/gene/MGI:3779637#orthology", "database": "AGR" }, { "id": "MGI:3644466", "url": "https://alliancegenome.org/gene/MGI:3644466#orthology", "database": "AGR" }, { "id": "FB:FBgn0031533", "url": "https://alliancegenome.org/gene/FB:FBgn0031533#orthology", "database": "AGR" }, { "id": "RGD:2321667", "url": "https://alliancegenome.org/gene/RGD:2321667#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M9PCU5-1", "protein_name": "3.1.-.-", "gene_name": "Lip4", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MCINSKNNTHIHPSGVVDCTLIALSLCLLQSGIVEGISLSLGDITLFNVNFKTPTFLGRSVAVDSNVRLENDVDPNIQEDSHLNTYSLIKKYGYPAENHTLETDDGYILTLHRIARPGATPVLLVHGLLDSSATWVMMGPNKGLGYLLYDQGYDVWMANVRGNTYSRKHVKYSTHHAKFWDFTFHEMGKHDIPATMDYILNSTGVSQLHYIGHSQGTVVFWIMASEKPEYMDKIILMQGLAPVAFLKHCRSPVVNFLAEWHLSVSLVLKLIGVHEFLPKNEFISMFNRIICDETTITKEICSNVIFLTTGFDKLQLNETMLPVIVGHSPAGASTKQMQHFGQLNRSGGFRQYDHGWLRNHWIYGTIDPPSYHLENVRAKVALYYGQNDWLAPPEDVEMLNRKLPNVVEKYLVDDKEFNHLDFIWGIDARELLWDRMLEIMRNHENSII", "length": 448 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" }, { "id": "RGD:708441", "url": "https://alliancegenome.org/gene/RGD:708441#orthology", "database": "AGR" }, { "id": "MGI:2679259", "url": "https://alliancegenome.org/gene/MGI:2679259#orthology", "database": "AGR" }, { "id": "MGI:1926003", "url": "https://alliancegenome.org/gene/MGI:1926003#orthology", "database": "AGR" }, { "id": "MGI:3779637", "url": "https://alliancegenome.org/gene/MGI:3779637#orthology", "database": "AGR" }, { "id": "MGI:3647308", "url": "https://alliancegenome.org/gene/MGI:3647308#orthology", "database": "AGR" }, { "id": "MGI:3647649", "url": "https://alliancegenome.org/gene/MGI:3647649#orthology", "database": "AGR" }, { "id": "MGI:1917416", "url": "https://alliancegenome.org/gene/MGI:1917416#orthology", "database": "AGR" }, { "id": "MGI:1914967", "url": "https://alliancegenome.org/gene/MGI:1914967#orthology", "database": "AGR" }, { "id": "MGI:3644466", "url": "https://alliancegenome.org/gene/MGI:3644466#orthology", "database": "AGR" }, { "id": "MGI:96789", "url": "https://alliancegenome.org/gene/MGI:96789#orthology", "database": "AGR" }, { "id": "RGD:1304912", "url": "https://alliancegenome.org/gene/RGD:1304912#orthology", "database": "AGR" }, { "id": "RGD:1565682", "url": "https://alliancegenome.org/gene/RGD:1565682#orthology", "database": "AGR" }, { "id": "RGD:1309724", "url": "https://alliancegenome.org/gene/RGD:1309724#orthology", "database": "AGR" }, { "id": "RGD:3008", "url": "https://alliancegenome.org/gene/RGD:3008#orthology", "database": "AGR" }, { "id": "RGD:1560354", "url": "https://alliancegenome.org/gene/RGD:1560354#orthology", "database": "AGR" }, { "id": "RGD:2321667", "url": "https://alliancegenome.org/gene/RGD:2321667#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "O46107-1", "protein_name": "Lipase 1", "gene_name": "Lip1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRCSLRMQLLLLLGLCVFISRIQGQLIGGEEDEEDEEEEEEEEESVEDETPEDRLQRKNIKQDSTLSVDKLIAKYGYESEVHHVTTEDGYILTMHRIRKQGAPPFLLQHGLVDSSAGFVVMGPNVSLAYLLADHNYDVWLGNARGNRYSRNHTTLDPDESKFWDFSWHEIGMYDLPAMIDHVLKVTGFPKLHYAGHSQGCTSFFVMCSMRPAYNDKVVSMQALAPAVYAKETEDHPYIRAISLYFNSLVGSSIREMFNGEFRFLCRMTEETERLCIEAVFGIVGRNWNEFNRKMFPVILGHYPAGVAAKQVKHFIQIIKSGRFAPYSYSSNKNMQLYRDHLPPRYNLSLVTVPTFVYYSTNDLLCHPKDVESMCDDLGNVTGKYLVPQKEFNHMDFLWAIDVRKMLYRRMLQVLGKVPEGSPEEANRSRREIRGKFIRS", "length": 439 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" }, { "id": "RGD:708441", "url": "https://alliancegenome.org/gene/RGD:708441#orthology", "database": "AGR" }, { "id": "MGI:2679259", "url": "https://alliancegenome.org/gene/MGI:2679259#orthology", "database": "AGR" }, { "id": "MGI:1926003", "url": "https://alliancegenome.org/gene/MGI:1926003#orthology", "database": "AGR" }, { "id": "MGI:3779637", "url": "https://alliancegenome.org/gene/MGI:3779637#orthology", "database": "AGR" }, { "id": "MGI:3647308", "url": "https://alliancegenome.org/gene/MGI:3647308#orthology", "database": "AGR" }, { "id": "MGI:3647649", "url": "https://alliancegenome.org/gene/MGI:3647649#orthology", "database": "AGR" }, { "id": "MGI:1917416", "url": "https://alliancegenome.org/gene/MGI:1917416#orthology", "database": "AGR" }, { "id": "MGI:1914967", "url": "https://alliancegenome.org/gene/MGI:1914967#orthology", "database": "AGR" }, { "id": "MGI:3644466", "url": "https://alliancegenome.org/gene/MGI:3644466#orthology", "database": "AGR" }, { "id": "MGI:96789", "url": "https://alliancegenome.org/gene/MGI:96789#orthology", "database": "AGR" }, { "id": "RGD:1304912", "url": "https://alliancegenome.org/gene/RGD:1304912#orthology", "database": "AGR" }, { "id": "RGD:1565682", "url": "https://alliancegenome.org/gene/RGD:1565682#orthology", "database": "AGR" }, { "id": "RGD:1309724", "url": "https://alliancegenome.org/gene/RGD:1309724#orthology", "database": "AGR" }, { "id": "RGD:3008", "url": "https://alliancegenome.org/gene/RGD:3008#orthology", "database": "AGR" }, { "id": "RGD:1560354", "url": "https://alliancegenome.org/gene/RGD:1560354#orthology", "database": "AGR" }, { "id": "RGD:2321667", "url": "https://alliancegenome.org/gene/RGD:2321667#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "O46108-1", "protein_name": "Lipase 3", "gene_name": "Lip3", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTRGALKVTILLVGLGLVLAGSRPISDCGERIEDDGYPMERHEVVTSDNYILTMHRIPYSPKTGESSNRPVAFLMHGMLSSSSDWVLMGPERSLAYMLADAGYDVWMGNARGNTYSKAHKYWPTYWQIFWNFSWNEIGMYDVPAMIDYVLAKTGQQQVQYVGHSQGTTVYLVMVSERPEYNDKIKSAHLLGPAAYMGNMKSPLTRAFAPILGQPNAIVEVCGSMEFMPSNKFKQDLGIEMCQATSPYADMCANEIFLIGGYDTEQLDYELLEHIKATSPAGASVNQNLHFCQEYNSGKFRKFDYTALRNPYEYGSYFPPDYKLKNAKAPVLLYYGANDWMCDVSDVRKLRDELPNMALDYLVPFEKWAHLDFIWGTEARKYVYDEVLKQMQSYE", "length": 394 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" }, { "id": "RGD:708441", "url": "https://alliancegenome.org/gene/RGD:708441#orthology", "database": "AGR" }, { "id": "MGI:2679259", "url": "https://alliancegenome.org/gene/MGI:2679259#orthology", "database": "AGR" }, { "id": "MGI:1926003", "url": "https://alliancegenome.org/gene/MGI:1926003#orthology", "database": "AGR" }, { "id": "MGI:3779637", "url": "https://alliancegenome.org/gene/MGI:3779637#orthology", "database": "AGR" }, { "id": "MGI:3647308", "url": "https://alliancegenome.org/gene/MGI:3647308#orthology", "database": "AGR" }, { "id": "MGI:3647649", "url": "https://alliancegenome.org/gene/MGI:3647649#orthology", "database": "AGR" }, { "id": "MGI:1917416", "url": "https://alliancegenome.org/gene/MGI:1917416#orthology", "database": "AGR" }, { "id": "MGI:1914967", "url": "https://alliancegenome.org/gene/MGI:1914967#orthology", "database": "AGR" }, { "id": "MGI:3644466", "url": "https://alliancegenome.org/gene/MGI:3644466#orthology", "database": "AGR" }, { "id": "MGI:96789", "url": "https://alliancegenome.org/gene/MGI:96789#orthology", "database": "AGR" }, { "id": "RGD:1304912", "url": "https://alliancegenome.org/gene/RGD:1304912#orthology", "database": "AGR" }, { "id": "RGD:1565682", "url": "https://alliancegenome.org/gene/RGD:1565682#orthology", "database": "AGR" }, { "id": "RGD:1309724", "url": "https://alliancegenome.org/gene/RGD:1309724#orthology", "database": "AGR" }, { "id": "RGD:3008", "url": "https://alliancegenome.org/gene/RGD:3008#orthology", "database": "AGR" }, { "id": "RGD:1560354", "url": "https://alliancegenome.org/gene/RGD:1560354#orthology", "database": "AGR" }, { "id": "RGD:2321667", "url": "https://alliancegenome.org/gene/RGD:2321667#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P04634-1", "protein_name": "Gastric triacylglycerol lipase", "gene_name": "Lipf", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWLLLITSVISTFGGAHGLFGKLGPGNPEANMNISQMITYWGYPCQEYEVVTEDGYILGVYRIPHGKNNSENIGKRPVVYLQHGLIASATNWIANLPNNSLAFMLADAGYDVWLGNSRGNTWSRKNVYYSPDSVEFWAFSFDEMAKYDLPATINFIVQKTGQEKIHYVGHSQGTTIGFIAFSTNPTLAKKIKTFYALAPVATVKYTQSPLKKISFIPTFLFKLMFGKKMFLPHTYFDDFLGTEVCSREVLDLLCSNTLFIFCGFDKKNLNVSRFDVYLGHNPAGTSVQDFLHWAQLVRSGKFQAFNWGSPSQNMLHYNQKTPPEYDVSAMTVPVAVWNGGNDILADPQDVAMLLPKLSNLLFHKEILAYNHLDFIWAMDAPQEVYNEMISMMAED", "length": 395 }, "evidence": [ { "id": "RGD:708441", "url": "https://alliancegenome.org/gene/RGD:708441#orthology", "database": "AGR" }, { "id": "MGI:1914967", "url": "https://alliancegenome.org/gene/MGI:1914967#orthology", "database": "AGR" }, { "id": "FB:FBgn0031533", "url": "https://alliancegenome.org/gene/FB:FBgn0031533#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P07098-1", "protein_name": "Gastric triacylglycerol lipase", "gene_name": "LIPF", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWLLLTMASLISVLGTTHGLFGKLHPGSPEVTMNISQMITYWGYPNEEYEVVTEDGYILEVNRIPYGKKNSGNTGQRPVVFLQHGLLASATNWISNLPNNSLAFILADAGYDVWLGNSRGNTWARRNLYYSPDSVEFWAFSFDEMAKYDLPATIDFIVKKTGQKQLHYVGHSQGTTIGFIAFSTNPSLAKRIKTFYALAPVATVKYTKSLINKLRFVPQSLFKFIFGDKIFYPHNFFDQFLATEVCSREMLNLLCSNALFIICGFDSKNFNTSRLDVYLSHNPAGTSVQNMFHWTQAVKSGKFQAYDWGSPVQNRMHYDQSQPPYYNVTAMNVPIAVWNGGKDLLADPQDVGLLLPKLPNLIYHKEIPFYNHLDFIWAMDAPQEVYNDIVSMISEDKK", "length": 398 }, "evidence": [ { "id": "RGD:708441", "url": "https://alliancegenome.org/gene/RGD:708441#orthology", "database": "AGR" }, { "id": "MGI:1914967", "url": "https://alliancegenome.org/gene/MGI:1914967#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P34163-1", "protein_name": "Sterol esterase TGL1", "gene_name": "TGL1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MYFPFLGRLSITDYIIVVLVYIESIISSVLKLIPQPMINLFEWLINFSTSSDDNTIEEKLRSAPTIHEMCAIFDISVEDHLVRTEDNYILTLHRIPPISKNRFNNKVVYLHHGLLMCSDVWCCNIERHKNLPFVLHDLGYDVWMGNNRGNKYSTAHLNKPPKSNKFWDFSIDEFAFFDIPNSIEFILDITKVDKVICIGFSQGSAQMFAAFSLSEKLNRKVSHFIAIAPAMTPKGLHNRIVDTLAKSSPGFMYLFFGRKIVLPSAVIWQRTLHPTLFNLCIDIANKILFNWKSFNILPRQKIASYAKLYSTTSVKSIVHWFQILRSQKFQMFEESDNMLNSLTRPYQIANFPTRTNIKIPILLIYGGIDSLVDIDVMKKNLPFNSVFDVKVDNYEHLDLIWGKDADTLVIAKVLRFIEFFNPGNVSVKTNQLLPSASLVEELPSTTWKTTHPTHGLSYRTHSADRSPLSVQADEADEVHNADNSRFLRRVFSTSAIDEDNENEHQDDTEDQIHKEQQRRLSAYLESSKDLRQLDANSSTTALDALNKE", "length": 548 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" }, { "id": "RGD:708441", "url": "https://alliancegenome.org/gene/RGD:708441#orthology", "database": "AGR" }, { "id": "MGI:2679259", "url": "https://alliancegenome.org/gene/MGI:2679259#orthology", "database": "AGR" }, { "id": "MGI:1926003", "url": "https://alliancegenome.org/gene/MGI:1926003#orthology", "database": "AGR" }, { "id": "MGI:3779637", "url": "https://alliancegenome.org/gene/MGI:3779637#orthology", "database": "AGR" }, { "id": "MGI:3647308", "url": "https://alliancegenome.org/gene/MGI:3647308#orthology", "database": "AGR" }, { "id": "MGI:3647649", "url": "https://alliancegenome.org/gene/MGI:3647649#orthology", "database": "AGR" }, { "id": "MGI:1917416", "url": "https://alliancegenome.org/gene/MGI:1917416#orthology", "database": "AGR" }, { "id": "MGI:1914967", "url": "https://alliancegenome.org/gene/MGI:1914967#orthology", "database": "AGR" }, { "id": "MGI:3644466", "url": "https://alliancegenome.org/gene/MGI:3644466#orthology", "database": "AGR" }, { "id": "MGI:96789", "url": "https://alliancegenome.org/gene/MGI:96789#orthology", "database": "AGR" }, { "id": "FB:FBgn0031533", "url": "https://alliancegenome.org/gene/FB:FBgn0031533#orthology", "database": "AGR" }, { "id": "RGD:1304912", "url": "https://alliancegenome.org/gene/RGD:1304912#orthology", "database": "AGR" }, { "id": "RGD:1565682", "url": "https://alliancegenome.org/gene/RGD:1565682#orthology", "database": "AGR" }, { "id": "RGD:1309724", "url": "https://alliancegenome.org/gene/RGD:1309724#orthology", "database": "AGR" }, { "id": "RGD:3008", "url": "https://alliancegenome.org/gene/RGD:3008#orthology", "database": "AGR" }, { "id": "RGD:1560354", "url": "https://alliancegenome.org/gene/RGD:1560354#orthology", "database": "AGR" }, { "id": "RGD:2321667", "url": "https://alliancegenome.org/gene/RGD:2321667#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P38571-1", "protein_name": "Lysosomal acid lipase/cholesteryl ester hydrolase", "gene_name": "LIPA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKMRFLGLVVCLVLWTLHSEGSGGKLTAVDPETNMNVSEIISYWGFPSEEYLVETEDGYILCLNRIPHGRKNHSDKGPKPVVFLQHGLLADSSNWVTNLANSSLGFILADAGFDVWMGNSRGNTWSRKHKTLSVSQDEFWAFSYDEMAKYDLPASINFILNKTGQEQVYYVGHSQGTTIGFIAFSQIPELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDHLIKDLFGDKEFLPQSAFLKWLGTHVCTHVILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAVKFQKFQAFDWGSSAKNYFHYNQSYPPTYNVKDMLVPTAVWSGGHDWLADVYDVNILLTQITNLVFHESIPEWEHLDFIWGLDAPWRLYNKIINLMRKYQ", "length": 399 }, "evidence": [ { "id": "MGI:96789", "url": "https://alliancegenome.org/gene/MGI:96789#orthology", "database": "AGR" }, { "id": "RGD:3008", "url": "https://alliancegenome.org/gene/RGD:3008#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q07804-1", "protein_name": "Sterol esterase 1", "gene_name": "YEH1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MGVSAVLKRARNLLATFIVCCFMAVVLVLALAHHFINEHRDTRSSSTQIEVDDESKRNVHHDHVLTRTNAYATPYLDLEHDKKNGIVYDHTRTVVRKKNHEVGSSSLHKNLFHKFLTKLIFRFIEKEKVTEGVTQGKFNNSSNEIANHEPVFEKIPVQCDNPLQNLILSEDLTLVADLNYYFNQYNIQIEEFRLETEDGFVIDLWHLIPKYRTTDSDKKKRPPILMLHGLLQSSGSFASNGRKSLAYFLYQSGYDIWLGNNRCGFRPEWNEAKVPTLASRWDWDLREMVKYDLTLLIDTVLAKTQFEKLTLISHSQGTTQGFMGLVNEDKFFPPGSGSKESFFTSKIANYIALAPAVYPGPLLNEKLFVKLMTKEIENPWFFGETSFFEIMMIVRNLCVGESLFSFVCYTIFNYLFDWNDTLWDTALRDRHFLFSPVHVSVKLMQWWLSPDPNKVSFKFGSHKMFPDNVKWFSDASKAPNIYLFVPKQDRLVDGERLINHFVNVESNVNYKIWYIDEYAHIDVLWAHDVIERIGKPILQNLNNYYSKKPSSAFESDCSDTEVETELEMVAEKA", "length": 573 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q07950-1", "protein_name": "Sterol esterase 2", "gene_name": "YEH2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVNKVVDEVQRLVSAIILTSFMTGLFILSLWKNYVTVHFQHKNDPRDTRSSRTKIQPNDKKKKRPARHSRPLSISSTTPLDLQRDQENNIEYDRTVTSKLSMTSNASLSENGDGNANIKMETNVNQAPYAAENPFQNIALAEDTKLVPDLKYYYKEYGIDIEEFEVETDDGFIIDLWHFKSRLNDGVEEVKREPILLLHGLLQSCGAFASSGRKSLAYFLYESGFDVWLGNNRCGLNAKWNMKKLGNDHSKKWDWDMHQMVQYDLKALINYVLDSTGYAKLSLVAHSQGTTQGFMGLVNGEKLYASDFKLVDKLENFVALAPAVYPGPLLDEKAFVRLMAKGIDSPWYFGRRSFIPLMMTMRKLMVGTKIFSFLSYIMFNYLFDWNDVLWDRVLRDRNFLFSPVHISVKLMQWWLSPLPNKLSFKKGAEKIFPDKKTWFPIAKNDDDSGNNLDNNKLHLNPKRQNSEEFPHIIMFIPKQDRLVDGERLINHFINHEANAVYKIWYIDEYSHLDVLWAHDVIDRIGKPMIENLRFPNAR", "length": 538 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q0KI77-1", "protein_name": "Lipase", "gene_name": "Dmel\\CG11598", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSYKAFVFFCLYIDLAKGLITSEIIASHNYPVEVHTVLTRDGYLLDAFRIPGSKFCQQSGPKPAVLFQHGMSASSDVFLLNGPQDSLAFMLADACFDVWLSNSRGTRYSRRHVSLDPSDEAFWRFSWHEIGTEDVAAFIDYILDTTKQRALHFLGHSQGCTTLVVLLSMRPEYNKLVKTAVLLAPAVFMRHTSTLSQTVFRSFIMAMPDKEFMYHNGVLNKLLSNVCGLFVARVFCTTFFLISNGKISKHLNTSVIPLIAATLPAGVSSRQPKHFIQLTDSGKFRPFDFGILRNLINYKSLEPPDYTLSNVRPLTPVHIFYSDDDSSTAKEDIQNFAARVPEVVMHRISTPGWHHTDFVHSMTVADVINKPVIEIFRSFERLSSPTFL", "length": 388 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" }, { "id": "RGD:708441", "url": "https://alliancegenome.org/gene/RGD:708441#orthology", "database": "AGR" }, { "id": "MGI:2679259", "url": "https://alliancegenome.org/gene/MGI:2679259#orthology", "database": "AGR" }, { "id": "MGI:1926003", "url": "https://alliancegenome.org/gene/MGI:1926003#orthology", "database": "AGR" }, { "id": "MGI:3779637", "url": "https://alliancegenome.org/gene/MGI:3779637#orthology", "database": "AGR" }, { "id": "MGI:3647308", "url": "https://alliancegenome.org/gene/MGI:3647308#orthology", "database": "AGR" }, { "id": "MGI:3647649", "url": "https://alliancegenome.org/gene/MGI:3647649#orthology", "database": "AGR" }, { "id": "MGI:1917416", "url": "https://alliancegenome.org/gene/MGI:1917416#orthology", "database": "AGR" }, { "id": "MGI:1914967", "url": "https://alliancegenome.org/gene/MGI:1914967#orthology", "database": "AGR" }, { "id": "MGI:3644466", "url": "https://alliancegenome.org/gene/MGI:3644466#orthology", "database": "AGR" }, { "id": "MGI:96789", "url": "https://alliancegenome.org/gene/MGI:96789#orthology", "database": "AGR" }, { "id": "RGD:1304912", "url": "https://alliancegenome.org/gene/RGD:1304912#orthology", "database": "AGR" }, { "id": "RGD:1565682", "url": "https://alliancegenome.org/gene/RGD:1565682#orthology", "database": "AGR" }, { "id": "RGD:1309724", "url": "https://alliancegenome.org/gene/RGD:1309724#orthology", "database": "AGR" }, { "id": "RGD:3008", "url": "https://alliancegenome.org/gene/RGD:3008#orthology", "database": "AGR" }, { "id": "RGD:1560354", "url": "https://alliancegenome.org/gene/RGD:1560354#orthology", "database": "AGR" }, { "id": "RGD:2321667", "url": "https://alliancegenome.org/gene/RGD:2321667#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q3U4B4-1", "protein_name": "Lipase member N", "gene_name": "Lipn", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPMMWLFLTTACLIPGTLSAGGFLDFENKVNPEVWMNASEIIMYNGYPSEEYDVTTADGYILAINRIPHGRAQTGQTGPRPVVYMQHALFADNAYWLENFANGSLGFILADAGYDVWMGNSRGNTWSRRHKTLSANEEKFWAFSFNEMAKYDLPGIIDFIVNKTGQEKLYFIGHSLGTTIGFVAFSTMPELAQRIKMNFALGPVISFKYPTSVFTNLFLLPKSIIKLVFGTKGVLLEDKNARMSFITFCNQKLLQPLCSEFMSLWAGFNKKNMNMSRLDVYMAHAPTGSSIQNMLHIKQLYRSDEFRAYDWGSEAENMNHYNQSYPPLYDLTAMKVPTAIWAGGHDVLVTPQDVARILPQITNLRYFKQFPDWNHFDFVWGLDAPQRLYSKIISLMKEYF", "length": 400 }, "evidence": [ { "id": "MGI:1917416", "url": "https://alliancegenome.org/gene/MGI:1917416#orthology", "database": "AGR" }, { "id": "FB:FBgn0031533", "url": "https://alliancegenome.org/gene/FB:FBgn0031533#orthology", "database": "AGR" }, { "id": "RGD:1560354", "url": "https://alliancegenome.org/gene/RGD:1560354#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q59E63-1", "protein_name": "Lipase", "gene_name": "Dmel\\CG11406", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAPEEEEPEEEVARDSLCTRSDSVCQAVQRQQLQCQVHRIETADGYRLSLHRIPAPQNRWCPQQLRPFLLMHGLLGSAGDFVSGGRGRSLALELHARCFDVWLANARGTTHSRGHRTLQTSDARFWRFSWHEIGIYDLPAIVDYVLARTNRRQLHYVGHSQGTTVLLVLLSQRPEYNARFANAALLAPVAFLQHLSSPPLRLLASDSSMATLLLNKLGLHELLPASALTQVGGQFFCTASRPTYALCTLFTSVYVGFSDYPLDRSILPRILETTPAGISRGQLQHFGQLINSGKFQQYDYRSPRLNTLRYGRTTPPSYQLANVRLQLQIFHGSRDTLSSLADVQRLVRELRNSVTQMYQVPGYNHIDFLFASSAPQVVFQRIIQQAWQLDMALAAL", "length": 396 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" }, { "id": "MGI:2679259", "url": "https://alliancegenome.org/gene/MGI:2679259#orthology", "database": "AGR" }, { "id": "MGI:1926003", "url": "https://alliancegenome.org/gene/MGI:1926003#orthology", "database": "AGR" }, { "id": "MGI:3779637", "url": "https://alliancegenome.org/gene/MGI:3779637#orthology", "database": "AGR" }, { "id": "MGI:3647308", "url": "https://alliancegenome.org/gene/MGI:3647308#orthology", "database": "AGR" }, { "id": "MGI:3647649", "url": "https://alliancegenome.org/gene/MGI:3647649#orthology", "database": "AGR" }, { "id": "MGI:1917416", "url": "https://alliancegenome.org/gene/MGI:1917416#orthology", "database": "AGR" }, { "id": "MGI:1914967", "url": "https://alliancegenome.org/gene/MGI:1914967#orthology", "database": "AGR" }, { "id": "MGI:3644466", "url": "https://alliancegenome.org/gene/MGI:3644466#orthology", "database": "AGR" }, { "id": "MGI:96789", "url": "https://alliancegenome.org/gene/MGI:96789#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q5VXI9-1", "protein_name": "Lipase member N", "gene_name": "LIPN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMWLLLTTTCLICGTLNAGGFLDLENEVNPEVWMNTSEIIIYNGYPSEEYEVTTEDGYILLVNRIPYGRTHARSTGPRPVVYMQHALFADNAYWLENYANGSLGFLLADAGYDVWMGNSRGNTWSRRHKTLSETDEKFWAFSFDEMAKYDLPGVIDFIVNKTGQEKLYFIGHSLGTTIGFVAFSTMPELAQRIKMNFALGPTISFKYPTGIFTRFFLLPNSIIKAVFGTKGFFLEDKKTKIASTKICNNKILWLICSEFMSLWAGSNKKNMNQSRMDVYMSHAPTGSSVHNILHIKQLYHSDEFRAYDWGNDADNMKHYNQSHPPIYDLTAMKVPTAIWAGGHDVLVTPQDVARILPQIKSLHYFKLLPDWNHFDFVWGLDAPQRMYSEIIALMKAYS", "length": 398 }, "evidence": [ { "id": "MGI:1917416", "url": "https://alliancegenome.org/gene/MGI:1917416#orthology", "database": "AGR" }, { "id": "RGD:1560354", "url": "https://alliancegenome.org/gene/RGD:1560354#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5VXJ0-1", "protein_name": "Lipase member K", "gene_name": "LIPK", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWQLLAAACWMLLLGSMYGYDKKGNNANPEANMNISQIISYWGYPYEEYDVTTKDGYILGIYRIPHGRGCPGRTAPKPAVYLQHGLIASASNWICNLPNNSLAFLLADSGYDVWLGNSRGNTWSRKHLKLSPKSPEYWAFSLDEMAKYDLPATINFIIEKTGQKRLYYVGHSQGTTIAFIAFSTNPELAKKIKIFFALAPVVTVKYTQSPMKKLTTLSRRVVKVLFGDKMFHPHTLFDQFIATKVCNRKLFRRICSNFLFTLSGFDPQNLNMSRLDVYLSHNPAGTSVQNMLHWAQAVNSGQLQAFDWGNSDQNMMHFHQLTPPLYNITKMEVPTAIWNGGQDIVADPKDVENLLPQIANLIYYKLIPHYNHVDFYLGEDAPQEIYQDLIILMEEYLQN", "length": 399 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" }, { "id": "MGI:2679259", "url": "https://alliancegenome.org/gene/MGI:2679259#orthology", "database": "AGR" }, { "id": "FB:FBgn0031533", "url": "https://alliancegenome.org/gene/FB:FBgn0031533#orthology", "database": "AGR" }, { "id": "RGD:1309724", "url": "https://alliancegenome.org/gene/RGD:1309724#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5VYY2-1", "protein_name": "Lipase member M", "gene_name": "LIPM", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLETLSRQWIVSHRMEMWLLILVAYMFQRNVNSVHMPTKAVDPEAFMNISEIIQHQGYPCEEYEVATEDGYILSVNRIPRGLVQPKKTGSRPVVLLQHGLVGGASNWISNLPNNSLGFILADAGFDVWMGNSRGNAWSRKHKTLSIDQDEFWAFSYDEMARFDLPAVINFILQKTGQEKIYYVGYSQGTTMGFIAFSTMPELAQKIKMYFALAPIATVKHAKSPGTKFLLLPDMMIKGLFGKKEFLYQTRFLRQLVIYLCGQVILDQICSNIMLLLGGFNTNNMNMSRASVYAAHTLAGTSVQNILHWSQAVNSGELRAFDWGSETKNLEKCNQPTPVRYRVRDMTVPTAMWTGGQDWLSNPEDVKMLLSEVTNLIYHKNIPEWAHVDFIWGLDAPHRMYNEIIHLMQQEETNLSQGRCEAVL", "length": 423 }, "evidence": [ { "id": "MGI:1926003", "url": "https://alliancegenome.org/gene/MGI:1926003#orthology", "database": "AGR" }, { "id": "RGD:1304912", "url": "https://alliancegenome.org/gene/RGD:1304912#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5W064-1", "protein_name": "Lipase member J", "gene_name": "LIPJ", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNISQIISYWGYPDEEYDIVTEDGYILGLYRIPYWRTDNNKNLAQRVVVYLQHGLLTSASSWISNLPNNSLGFILADAGYDVWMGNSRGNTWSRKHLYLETSSKEFWAFSFDEMAKYDLPASIDFTVKQTRQEEIFYVGHSQGTTIGFITFSTISKIAERIKIFFALAPVFSTKYLKSPLIRMTYKWKSIVMAFSGNKDFLPKTSFKKFIGSKLCPLQIFDKICLNILFMMFGYDPKNLNMSRLDVYFSHNPAGTSVQNMLHWSQLLNSTHLKAYDWGSPDLNLVHYNQTTSPLYNMTNMNVATAIWNGKSDLLADPEDVNILHSEITNHIYYKTISYYNHIDSLFGLDVYDQVYHEIIDIIQDNL", "length": 366 }, "evidence": [ { "id": "RGD:2321667", "url": "https://alliancegenome.org/gene/RGD:2321667#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q64194-1", "protein_name": "Lysosomal acid lipase/cholesteryl ester hydrolase", "gene_name": "Lipa", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQLLGRVICFVVGILLSGGPTGTISAVDPEANMNVTEIIMHWGYPEHSVQTGDGYILGVHRIPHGRKNQFDKGPKPVVYLQWRHGFLADSSNWVTNIDNNSLGFILADAGFDVWMGNSRGNTWSRKHKTLSVSQDEYWAFSFDEMAKYDLPASINYILNKTGQEQLYNVGHSQGCTIGFIAFSQMPELAKKVKMFFALAPVLSLNFASGPMVKLGRLPDLLLEDLFGQKQFLPQSAMVKWLSTHICTHVIMKELCANIFFLICGFNEKNLNMSRVDVYTTHCPAGTSVQNMVHWTQVVKYHKLQAFDWGSSDKNYFHYNQSYPPLYSIKDMQLPTALWSGGKDWLADTSDINILLTEIPTLVYHKNIPEWDHLDFIWGLDAPWRLYNEVVSLMKKYQ", "length": 397 }, "evidence": [ { "id": "MGI:96789", "url": "https://alliancegenome.org/gene/MGI:96789#orthology", "database": "AGR" }, { "id": "FB:FBgn0031533", "url": "https://alliancegenome.org/gene/FB:FBgn0031533#orthology", "database": "AGR" }, { "id": "RGD:3008", "url": "https://alliancegenome.org/gene/RGD:3008#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BM14-1", "protein_name": "Lipase member K", "gene_name": "Lipk", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWWLLATTCCVLLSGPIDGYKQESITNPEANMNISELISYWGYPYEKHDVITEDGYILGTYRIPHGKGCSRKTAPKAVVYLQHGLIASANNWICNLPNNSLAFLLADSGYDVWLGNSRGNTWSRNHLRLSPKSPQYWAFSWDEMAKYDLPATVNLILEKSGQKQLFYVGHSQGTTIAFIAFSTNPELAKKIRLFFALAPVATVKYTRSPMKKLTTLSRKAVKVLFGDKMFSTHTWFEQFIATKVCNRKLFHQLCSNFLFSLSGFDPQNLNMSRLDVYLSQSPAGTSVQNMLHWAQAVNSGQLQAFDWGNPDQNMMHFNQLTPPVYNISKMRVPTAMWSGGQDVVADAKDTKNLLPKIANLIYYKEIPHYNHMDFYLGQDAPQEVYGDLIRMIEESLQN", "length": 398 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" }, { "id": "MGI:2679259", "url": "https://alliancegenome.org/gene/MGI:2679259#orthology", "database": "AGR" }, { "id": "FB:FBgn0031533", "url": "https://alliancegenome.org/gene/FB:FBgn0031533#orthology", "database": "AGR" }, { "id": "RGD:1309724", "url": "https://alliancegenome.org/gene/RGD:1309724#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IMS3-1", "protein_name": "Lipase", "gene_name": "CG5990", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MYRSHIAVICAFVGIFVGTVVQSAPFSNDPAEVPNFYELFNNPDAHLSLTNGPDTIHFIEEHGYPVERHYVTTEDGYIISLFRIPYSHNIQNQQEKRPIAFIQHGLFASSDFWPSLGPDDGLPFLLSDAGYDVWLGNARGNRYSKNHTSRLTSHPDFWRFSWHEIGYFDIAAAIDYTLSTENGQDQKGIHYIGHSQGTTVMFVLLSSRPEYNDKIKTAHMLAPVAFMDHMDDVMVNTLSPYLGFNNIYSTLFCSQEFLPHNDFVLALMYSVCLPESIVYSFCSSSNETTTEEGRTNSTASALTSGVMPAGVSTDQILHYMQEHQSGHFRQFDFGTKKNMKVYGTEAPEDYPTELITAEMHLWYSDSDEMAAVEDVLRVAETLPNKVMHHMEDPLWDHMDFALNWEVRQYINDPIVAILNEYEGK", "length": 424 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" }, { "id": "RGD:708441", "url": "https://alliancegenome.org/gene/RGD:708441#orthology", "database": "AGR" }, { "id": "MGI:2679259", "url": "https://alliancegenome.org/gene/MGI:2679259#orthology", "database": "AGR" }, { "id": "MGI:1926003", "url": "https://alliancegenome.org/gene/MGI:1926003#orthology", "database": "AGR" }, { "id": "MGI:3779637", "url": "https://alliancegenome.org/gene/MGI:3779637#orthology", "database": "AGR" }, { "id": "MGI:3647308", "url": "https://alliancegenome.org/gene/MGI:3647308#orthology", "database": "AGR" }, { "id": "MGI:3647649", "url": "https://alliancegenome.org/gene/MGI:3647649#orthology", "database": "AGR" }, { "id": "MGI:1917416", "url": "https://alliancegenome.org/gene/MGI:1917416#orthology", "database": "AGR" }, { "id": "MGI:1914967", "url": "https://alliancegenome.org/gene/MGI:1914967#orthology", "database": "AGR" }, { "id": "MGI:3644466", "url": "https://alliancegenome.org/gene/MGI:3644466#orthology", "database": "AGR" }, { "id": "MGI:96789", "url": "https://alliancegenome.org/gene/MGI:96789#orthology", "database": "AGR" }, { "id": "RGD:1304912", "url": "https://alliancegenome.org/gene/RGD:1304912#orthology", "database": "AGR" }, { "id": "RGD:1565682", "url": "https://alliancegenome.org/gene/RGD:1565682#orthology", "database": "AGR" }, { "id": "RGD:1309724", "url": "https://alliancegenome.org/gene/RGD:1309724#orthology", "database": "AGR" }, { "id": "RGD:3008", "url": "https://alliancegenome.org/gene/RGD:3008#orthology", "database": "AGR" }, { "id": "RGD:1560354", "url": "https://alliancegenome.org/gene/RGD:1560354#orthology", "database": "AGR" }, { "id": "RGD:2321667", "url": "https://alliancegenome.org/gene/RGD:2321667#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8K2A6-1", "protein_name": "Lipase member M", "gene_name": "Lipm", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSEILSRVWTVSHRVEIWLLILVAYLLQRNVNSGHLPTKAADPEAFMNVSEIIKHKGYPSEEYEVATEDGYILSVNRIPRGQTRLKKEGSRPVVLLQHGLLGDASNWISNLPNNSLGFILADAGFDVWMGNSRGNTWSRKHKTLSIDQDEFWAFSYDEMARFDLPAVINFILQKTGQKKVYYVGYSQGTTMGFIAFSTMPELAHKIKMYFALAPIATVKYARSPGTKFLLLPDMMIKVLFGRQEFLYQTRFFRQLFIYLCGQMILDQICSNIILLLGGFNTNNMNMSRANVYVAHTPAGTSVQNILHWSQAVNSGELRAFDWGSETKNQEKCNQPTPIRYKVRDMMVPTAMWTGGQDWLSNPDDVKTLLSEVTNLIYHKNIPEWAHVDFIWGLDAPQRVYNEIIHLMKQEPNLPQGTCRVKL", "length": 422 }, "evidence": [ { "id": "MGI:1926003", "url": "https://alliancegenome.org/gene/MGI:1926003#orthology", "database": "AGR" }, { "id": "FB:FBgn0031533", "url": "https://alliancegenome.org/gene/FB:FBgn0031533#orthology", "database": "AGR" }, { "id": "RGD:1304912", "url": "https://alliancegenome.org/gene/RGD:1304912#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9CPP7-1", "protein_name": "Gastric triacylglycerol lipase", "gene_name": "Lipf", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWLLLVTSVLSAFGGAHGLFGKLGPKNPEANMNVSQMITYWGYPSEEYEVVTEDGYILGVYRIPYGKKNSENIGKRPVAYLQHGLIASATNWITNLPNNSLAFILADAGYDVWLGNSRGNTWSRKNVYYSPDSVEFWAFSFDEMAKYDLPATIDFIVQKTGQEKIHYVGHSQGTTIGFIAFSTNPALAKKIKRFYALAPVATVKYTESPFKKISLIPKFLLKVIFGNKMFMPHNYLDQFLGTEVCSRELLDLLCSNALFIFCGFDKKNLNVSRFDVYLGHNPAGTSTQDLFHWAQLAKSGKLQAYNWGSPLQNMLHYNQKTPPYYDVSAMTVPIAVWNGGHDILADPQDVAMLLPKLPNLLYHKEILPYNHLDFIWAMDAPQEVYNEIVTMMAED", "length": 395 }, "evidence": [ { "id": "RGD:708441", "url": "https://alliancegenome.org/gene/RGD:708441#orthology", "database": "AGR" }, { "id": "MGI:1914967", "url": "https://alliancegenome.org/gene/MGI:1914967#orthology", "database": "AGR" }, { "id": "FB:FBgn0031533", "url": "https://alliancegenome.org/gene/FB:FBgn0031533#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9V9N3-1", "protein_name": "Lipase", "gene_name": "Dmel\\CG3635", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLDNNSCAQTNILTSKEMANNSPTRGSVMLLTLVLLLLSRKIGLVDGHKVTATSISNHNYPVEEHTVITHDDYILTIYRIPSSPNRSHLNRAGRRAVVFLQHGILSASDDWIINGPEASLAYMLADAGYDVWLGNARGNTYSRQHKHIHPDTSDFWRFSWHEIGVYDLAAMLDYALAKSQSSSLHFVAHSQGTTAFFVLMSSLPLYNEKLRSVHLLAPIAYMRDHSFILSKLGGIFLGTPSFLSWVLGSMELLPITNLQKLICEHICSSSSMFNFLCSGLLDFIGGWGTRHLNQTLLPDVCATHPAGASSSQVIHYLQLYRSGDFRQYDHGPELNEIIYQQPTPPSYNVQYIKSCVDMYYSENDYMSAVGDVKYLASLLPCAQLYRIPFRDWNHYDFLWSNNVKEVINNKIIQKIRKYDEDGVGF", "length": 425 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" }, { "id": "RGD:708441", "url": "https://alliancegenome.org/gene/RGD:708441#orthology", "database": "AGR" }, { "id": "MGI:2679259", "url": "https://alliancegenome.org/gene/MGI:2679259#orthology", "database": "AGR" }, { "id": "MGI:1926003", "url": "https://alliancegenome.org/gene/MGI:1926003#orthology", "database": "AGR" }, { "id": "MGI:3779637", "url": "https://alliancegenome.org/gene/MGI:3779637#orthology", "database": "AGR" }, { "id": "MGI:3647308", "url": "https://alliancegenome.org/gene/MGI:3647308#orthology", "database": "AGR" }, { "id": "MGI:3647649", "url": "https://alliancegenome.org/gene/MGI:3647649#orthology", "database": "AGR" }, { "id": "MGI:1917416", "url": "https://alliancegenome.org/gene/MGI:1917416#orthology", "database": "AGR" }, { "id": "MGI:1914967", "url": "https://alliancegenome.org/gene/MGI:1914967#orthology", "database": "AGR" }, { "id": "MGI:3644466", "url": "https://alliancegenome.org/gene/MGI:3644466#orthology", "database": "AGR" }, { "id": "MGI:96789", "url": "https://alliancegenome.org/gene/MGI:96789#orthology", "database": "AGR" }, { "id": "RGD:1304912", "url": "https://alliancegenome.org/gene/RGD:1304912#orthology", "database": "AGR" }, { "id": "RGD:1565682", "url": "https://alliancegenome.org/gene/RGD:1565682#orthology", "database": "AGR" }, { "id": "RGD:1309724", "url": "https://alliancegenome.org/gene/RGD:1309724#orthology", "database": "AGR" }, { "id": "RGD:3008", "url": "https://alliancegenome.org/gene/RGD:3008#orthology", "database": "AGR" }, { "id": "RGD:1560354", "url": "https://alliancegenome.org/gene/RGD:1560354#orthology", "database": "AGR" }, { "id": "RGD:2321667", "url": "https://alliancegenome.org/gene/RGD:2321667#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VBK6-1", "protein_name": "Lipase", "gene_name": "CG5990", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNRFTGSLLVLVALAVGVYSAAIDGPIDFYKLYDNPEAHISLKSKITTADRTAAHGYPSEHHHIVTEDGYILGVFRIPYSHKLQNQNEKRPIVLLQHGLTSCSDAWILQGPNDGLPYLLADAGFDVWMGNARGTSYSRNHTTLSPDHPNFWKFSWHEIGIYDITAIIDYALSTENGQGQDAIHYVGHSQGTTVFFALMSWIPEYNDKIKTAHMFAPVAIMKNLSSGLVRSVGPYLGHRNTYSVLFGSQEFLPHNEFLMAIFFNICQPDFMLRPVCESAMEKLYAGGRVNMTAMPEGMATHPAGCSTDQMLHYLQEQQSGYFRLFDHGTKKNLEVYGTQEPPEYPVELINSLVHMWYADSDNLAAVEDVEQIAERLPNKVMHRMADTEWNHGDFALNWEVRKYINEPVIDIMMEYELKNIGT", "length": 421 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" }, { "id": "RGD:708441", "url": "https://alliancegenome.org/gene/RGD:708441#orthology", "database": "AGR" }, { "id": "MGI:2679259", "url": "https://alliancegenome.org/gene/MGI:2679259#orthology", "database": "AGR" }, { "id": "MGI:1926003", "url": "https://alliancegenome.org/gene/MGI:1926003#orthology", "database": "AGR" }, { "id": "MGI:3779637", "url": "https://alliancegenome.org/gene/MGI:3779637#orthology", "database": "AGR" }, { "id": "MGI:3647308", "url": "https://alliancegenome.org/gene/MGI:3647308#orthology", "database": "AGR" }, { "id": "MGI:3647649", "url": "https://alliancegenome.org/gene/MGI:3647649#orthology", "database": "AGR" }, { "id": "MGI:1917416", "url": "https://alliancegenome.org/gene/MGI:1917416#orthology", "database": "AGR" }, { "id": "MGI:1914967", "url": "https://alliancegenome.org/gene/MGI:1914967#orthology", "database": "AGR" }, { "id": "MGI:3644466", "url": "https://alliancegenome.org/gene/MGI:3644466#orthology", "database": "AGR" }, { "id": "MGI:96789", "url": "https://alliancegenome.org/gene/MGI:96789#orthology", "database": "AGR" }, { "id": "RGD:1304912", "url": "https://alliancegenome.org/gene/RGD:1304912#orthology", "database": "AGR" }, { "id": "RGD:1565682", "url": "https://alliancegenome.org/gene/RGD:1565682#orthology", "database": "AGR" }, { "id": "RGD:1309724", "url": "https://alliancegenome.org/gene/RGD:1309724#orthology", "database": "AGR" }, { "id": "RGD:3008", "url": "https://alliancegenome.org/gene/RGD:3008#orthology", "database": "AGR" }, { "id": "RGD:1560354", "url": "https://alliancegenome.org/gene/RGD:1560354#orthology", "database": "AGR" }, { "id": "RGD:2321667", "url": "https://alliancegenome.org/gene/RGD:2321667#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VG46-1", "protein_name": "Lipase", "gene_name": "Dmel\\CG6753", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRRERVVLLCLALLGLQQVSRATLRQSREIIITDAVRRIQNDGYNVERHSVTTKDGYVLTLHRIPQVDPELGSLLRRPVVFLLSGLYASSDVWLLNGREDSLAYLLWRAGYDVWLGNNRGNIYCRKNMWRNTTEREFWDFSWHEMGVYDLPAQVDYVLRTTGQKAMHFVGISQGGTVFLVLNSMMPQYNAVFKSATLLAPVAYVSNTKSGLAKVIGPVLGTRNYVSKMLEGVEMFSTNKFFKKFLSMTCLENEKPLVCISRLWPAVGYDTRFLNKTLLPDLMANFPAGGSVKQLMHYFQGYVSTRFRQYDYGPERNWLHYQQLEPPEYALENVSTPVTVFFSENDYIVAPADIWRLLTRLPNVEAVYKVPWKRWNHFDFICGLGVREYIFDNIVLSMNRYEQRRR", "length": 405 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" }, { "id": "RGD:708441", "url": "https://alliancegenome.org/gene/RGD:708441#orthology", "database": "AGR" }, { "id": "MGI:2679259", "url": "https://alliancegenome.org/gene/MGI:2679259#orthology", "database": "AGR" }, { "id": "MGI:1926003", "url": "https://alliancegenome.org/gene/MGI:1926003#orthology", "database": "AGR" }, { "id": "MGI:3779637", "url": "https://alliancegenome.org/gene/MGI:3779637#orthology", "database": "AGR" }, { "id": "MGI:3647308", "url": "https://alliancegenome.org/gene/MGI:3647308#orthology", "database": "AGR" }, { "id": "MGI:3647649", "url": "https://alliancegenome.org/gene/MGI:3647649#orthology", "database": "AGR" }, { "id": "MGI:1917416", "url": "https://alliancegenome.org/gene/MGI:1917416#orthology", "database": "AGR" }, { "id": "MGI:1914967", "url": "https://alliancegenome.org/gene/MGI:1914967#orthology", "database": "AGR" }, { "id": "MGI:3644466", "url": "https://alliancegenome.org/gene/MGI:3644466#orthology", "database": "AGR" }, { "id": "MGI:96789", "url": "https://alliancegenome.org/gene/MGI:96789#orthology", "database": "AGR" }, { "id": "RGD:1304912", "url": "https://alliancegenome.org/gene/RGD:1304912#orthology", "database": "AGR" }, { "id": "RGD:1565682", "url": "https://alliancegenome.org/gene/RGD:1565682#orthology", "database": "AGR" }, { "id": "RGD:1309724", "url": "https://alliancegenome.org/gene/RGD:1309724#orthology", "database": "AGR" }, { "id": "RGD:3008", "url": "https://alliancegenome.org/gene/RGD:3008#orthology", "database": "AGR" }, { "id": "RGD:1560354", "url": "https://alliancegenome.org/gene/RGD:1560354#orthology", "database": "AGR" }, { "id": "RGD:2321667", "url": "https://alliancegenome.org/gene/RGD:2321667#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VG47-1", "protein_name": "Lipase", "gene_name": "Dmel\\CG11608", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MQSFLIQMLPILLGIFFVWLSNSTALSEVNWKNHSLHRIHHRTKVITAVDIISSHNYPVQTHTVVTRDGYILSVFRIPSSQLCASSEPKPVVLINHGMTGSADSWLLTGPRNGLPFLLADACYDVWLINCRGTRYSRKHLKLKAWLLQFWRFSWHEIGMEDLPATVDHILASTKRNSLHYVGHSQGCTSMLVMLSMRPEYNKRIRTTILLAPPVFLKHSLSMGHKIMKPLFNLLPDIELLPHHKMLNSAVSAICKILGVKDVCTALYLLTNGRVSQHMNRTLIPMLIATHPAGISSRQPRHFFQLKDSGRFRQYDFGFGMNYLIYRQNTPPEYPLEMVRPHSAIHIFYSDDDGTISPRDVLTLASKLPYAVPHHITDETWNHMDFLLANNINELINNPVIKIIKTFEENIKHKIGNIKGEISIDALLNEF", "length": 430 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" }, { "id": "RGD:708441", "url": "https://alliancegenome.org/gene/RGD:708441#orthology", "database": "AGR" }, { "id": "MGI:2679259", "url": "https://alliancegenome.org/gene/MGI:2679259#orthology", "database": "AGR" }, { "id": "MGI:1926003", "url": "https://alliancegenome.org/gene/MGI:1926003#orthology", "database": "AGR" }, { "id": "MGI:3779637", "url": "https://alliancegenome.org/gene/MGI:3779637#orthology", "database": "AGR" }, { "id": "MGI:3647308", "url": "https://alliancegenome.org/gene/MGI:3647308#orthology", "database": "AGR" }, { "id": "MGI:3647649", "url": "https://alliancegenome.org/gene/MGI:3647649#orthology", "database": "AGR" }, { "id": "MGI:1917416", "url": "https://alliancegenome.org/gene/MGI:1917416#orthology", "database": "AGR" }, { "id": "MGI:1914967", "url": "https://alliancegenome.org/gene/MGI:1914967#orthology", "database": "AGR" }, { "id": "MGI:3644466", "url": "https://alliancegenome.org/gene/MGI:3644466#orthology", "database": "AGR" }, { "id": "MGI:96789", "url": "https://alliancegenome.org/gene/MGI:96789#orthology", "database": "AGR" }, { "id": "RGD:1304912", "url": "https://alliancegenome.org/gene/RGD:1304912#orthology", "database": "AGR" }, { "id": "RGD:1565682", "url": "https://alliancegenome.org/gene/RGD:1565682#orthology", "database": "AGR" }, { "id": "RGD:1309724", "url": "https://alliancegenome.org/gene/RGD:1309724#orthology", "database": "AGR" }, { "id": "RGD:3008", "url": "https://alliancegenome.org/gene/RGD:3008#orthology", "database": "AGR" }, { "id": "RGD:1560354", "url": "https://alliancegenome.org/gene/RGD:1560354#orthology", "database": "AGR" }, { "id": "RGD:2321667", "url": "https://alliancegenome.org/gene/RGD:2321667#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VG48-1", "protein_name": "Lipase", "gene_name": "Dmel\\CG11600", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLLMELVIFFDWLLIVSGMPKVKFGLQNFTGRGKDYRIKVITGILIIDKYGYSVETHTVRTGDGYILDMFRIPSSPNCKEDGFKPSVLIQHGLISLADSFLVTGPRSGLPFMLADRCYDVWLSNSRGVRYSQRHIRLKASQDAFWRFSWHEMGMEDLPAMIDYILSTTNEEALHFVCHSQGCTTLLVLLSMKPEYNRMIKTANMMAPAVFMKHARNKLMKMFGNIIMSMKDSSFFGPLDAIRFLLSVFCKCSKFKKLCAFMFILASEEPTSYMNNTAIPLILATHPGAISTRQPKHFLQLRKSGKFRPYDFGVMRNKKLYNQDTPPDYPLENVRPQSPIHIYHSHGDDLVARKDIHILISKLDKAVLHDVVFEKWSHSDFLFAKLIKKVVNEPIIKVIDHFENRQQ", "length": 406 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" }, { "id": "RGD:708441", "url": "https://alliancegenome.org/gene/RGD:708441#orthology", "database": "AGR" }, { "id": "MGI:2679259", "url": "https://alliancegenome.org/gene/MGI:2679259#orthology", "database": "AGR" }, { "id": "MGI:1926003", "url": "https://alliancegenome.org/gene/MGI:1926003#orthology", "database": "AGR" }, { "id": "MGI:3779637", "url": "https://alliancegenome.org/gene/MGI:3779637#orthology", "database": "AGR" }, { "id": "MGI:3647308", "url": "https://alliancegenome.org/gene/MGI:3647308#orthology", "database": "AGR" }, { "id": "MGI:3647649", "url": "https://alliancegenome.org/gene/MGI:3647649#orthology", "database": "AGR" }, { "id": "MGI:1917416", "url": "https://alliancegenome.org/gene/MGI:1917416#orthology", "database": "AGR" }, { "id": "MGI:1914967", "url": "https://alliancegenome.org/gene/MGI:1914967#orthology", "database": "AGR" }, { "id": "MGI:3644466", "url": "https://alliancegenome.org/gene/MGI:3644466#orthology", "database": "AGR" }, { "id": "MGI:96789", "url": "https://alliancegenome.org/gene/MGI:96789#orthology", "database": "AGR" }, { "id": "RGD:1304912", "url": "https://alliancegenome.org/gene/RGD:1304912#orthology", "database": "AGR" }, { "id": "RGD:1565682", "url": "https://alliancegenome.org/gene/RGD:1565682#orthology", "database": "AGR" }, { "id": "RGD:1309724", "url": "https://alliancegenome.org/gene/RGD:1309724#orthology", "database": "AGR" }, { "id": "RGD:3008", "url": "https://alliancegenome.org/gene/RGD:3008#orthology", "database": "AGR" }, { "id": "RGD:1560354", "url": "https://alliancegenome.org/gene/RGD:1560354#orthology", "database": "AGR" }, { "id": "RGD:2321667", "url": "https://alliancegenome.org/gene/RGD:2321667#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VG50-1", "protein_name": "Lipase", "gene_name": "CG12294", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPYKTLVILSVCTQIVNGITSAEIIASHNYPVEIHTVVTRDGYLLNAFRIPNSIYCEQSGTKPAVLFQHGMTASSDVFLVNGPRDALPFMLADACFDVWLSNSRGTRYSRRHVSLDPSDEDFWRFSWHEIGTEDVAAFIDYILGTTNQSAVHYVGHSQGCTTLVVLLSMRPEYNQFVKTAILLGPPVFMGHTHTLGQIFLRTLIMSMPDCEFMFHNRILNKILRRICGLFVVRVYCSTFFMIVNGKFSDHLNTSAIPLIAATLPAGVSSRQPKHFIQLTDSGRFRPFDFGILRNLINYRSLTPPDYPLHNVRPLTPVHIFYSDDDLSAAKEDVENFATSLPEAVMHRISTPSWHHMDFVHSMTVANVINKPVIEIFKRFEQPIDCKGSL", "length": 389 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" }, { "id": "RGD:708441", "url": "https://alliancegenome.org/gene/RGD:708441#orthology", "database": "AGR" }, { "id": "RGD:1304912", "url": "https://alliancegenome.org/gene/RGD:1304912#orthology", "database": "AGR" }, { "id": "RGD:1565682", "url": "https://alliancegenome.org/gene/RGD:1565682#orthology", "database": "AGR" }, { "id": "RGD:1309724", "url": "https://alliancegenome.org/gene/RGD:1309724#orthology", "database": "AGR" }, { "id": "RGD:3008", "url": "https://alliancegenome.org/gene/RGD:3008#orthology", "database": "AGR" }, { "id": "RGD:1560354", "url": "https://alliancegenome.org/gene/RGD:1560354#orthology", "database": "AGR" }, { "id": "RGD:2321667", "url": "https://alliancegenome.org/gene/RGD:2321667#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VKR5-1", "protein_name": "Lipase", "gene_name": "Lip2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGGSGCIGAIKVMLIVCAIGRNAHSSPPESRYKWTTMDWLEAQNVSHEVHNVTTADGYQLQLQRLPRLGAKPVLLVHGLLGSSLGWVCMGPERSLAFQLHHREYDVWLANLRGVSPYGRQHIDLTDVMVEFWRFSFHEHGAYDLPAIIDHMAKVTGGEQLASRGGPGQDEEQIHHQVVLIGHSQAFNAFLVLCAVHPRFNQRIQLIQALAPLARLHRQVRFDSFQVRRLMKFIKKRQKAYKFEIFPPGYFRKVCQAKRDLCEYYAKQLVGSAQNNKKLLEAFNYEYLLQGGSPREIKHLQQIWKSGDFISYDFGTAENLQVYHSVEALSYNISQITVPIILYFGETDAIATPEGVHAIYARMLRSVKSVRRINSKKFNHLDFLISGDVKSLVNDKLIEHMEQFFDGRLPYVIE", "length": 413 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VKS5-1", "protein_name": "Partial AB-hydrolase lipase domain-containing protein", "gene_name": "CG17099", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRSTVEVKGRLLLTLLLHCLVALEVCGRAGAFTLLSPFSYSSLSFKNLLNSVLLSSNPNLAGGGRNLKSDVLEDASLITPKLIRKYGYPSETHTVVTKDGYILEMHRIPKKGAQPVLLMHGILDTSATWVLMGPKSGLGYMLSDLGYDVWMGNSRGNRYSKNHTSLNSDYQEFWDFTFHEMGKYDLPANIDYILSKTGYEQVHYIGHSQGTAIFWVLCSEQPAYTQKITSMHALAPIAYIHDMKSPLFRTLVLFLDFLTAATRMLRITEFMPNTKFLVDHSQVVCHDNAMTQDVCSNILFLVAGYNSEQLNKTMLPVMLSHTPSGASIKQLEHFGQLMKSGHFRKFDRGYLRNQLEYNRMTPPDYDLSRVKVPVALYYSVNDLLVSTTGVDRLARELPNVIDKYLVPMERFNHLDFLWAIDVKPLVYNRLVRNVRRVENHRAKLTANLANYLAMQLQRQQLRQQMQQQMMEGLPPNVHLPHGLGMEMLARATTFAPVTHPTTTMTMPTTTTENDAEDEVLTTAATATEVPA", "length": 531 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" }, { "id": "RGD:708441", "url": "https://alliancegenome.org/gene/RGD:708441#orthology", "database": "AGR" }, { "id": "MGI:2679259", "url": "https://alliancegenome.org/gene/MGI:2679259#orthology", "database": "AGR" }, { "id": "MGI:1926003", "url": "https://alliancegenome.org/gene/MGI:1926003#orthology", "database": "AGR" }, { "id": "MGI:3779637", "url": "https://alliancegenome.org/gene/MGI:3779637#orthology", "database": "AGR" }, { "id": "MGI:3647308", "url": "https://alliancegenome.org/gene/MGI:3647308#orthology", "database": "AGR" }, { "id": "MGI:3647649", "url": "https://alliancegenome.org/gene/MGI:3647649#orthology", "database": "AGR" }, { "id": "MGI:1917416", "url": "https://alliancegenome.org/gene/MGI:1917416#orthology", "database": "AGR" }, { "id": "MGI:1914967", "url": "https://alliancegenome.org/gene/MGI:1914967#orthology", "database": "AGR" }, { "id": "MGI:3644466", "url": "https://alliancegenome.org/gene/MGI:3644466#orthology", "database": "AGR" }, { "id": "MGI:96789", "url": "https://alliancegenome.org/gene/MGI:96789#orthology", "database": "AGR" }, { "id": "RGD:1304912", "url": "https://alliancegenome.org/gene/RGD:1304912#orthology", "database": "AGR" }, { "id": "RGD:1565682", "url": "https://alliancegenome.org/gene/RGD:1565682#orthology", "database": "AGR" }, { "id": "RGD:1309724", "url": "https://alliancegenome.org/gene/RGD:1309724#orthology", "database": "AGR" }, { "id": "RGD:3008", "url": "https://alliancegenome.org/gene/RGD:3008#orthology", "database": "AGR" }, { "id": "RGD:1560354", "url": "https://alliancegenome.org/gene/RGD:1560354#orthology", "database": "AGR" }, { "id": "RGD:2321667", "url": "https://alliancegenome.org/gene/RGD:2321667#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VKS9-1", "protein_name": "Partial AB-hydrolase lipase domain-containing protein", "gene_name": "Acp", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAIAFNIAIYAIILVGSLVPSKTQEWVPYAYPVDENQGLNEQTQWQSQSQIQSQGTSQSQSQAQIQSQPEPRSCLQCQQASYQQFFAEVDIQIDAKLETPKMISKYGHQVETHYAFTADGYKLCLHRIPRSGATPVLLVHGLMASSATWVQFGPSQGLAYILSQSGYDVWMLNTRGNVYSEERLAGRESDKIFWDFSFHEIGQYDLPAAIDLILLQTKMPSIQYIGHSQGSTAFFVMCSERPEYAGKISLMQSLSPSVYMEGTRSPALKFMKLFSGGFTMLLNLLGGHKISLKNKIVDMFRNHICTKLIPSRICAIFEFVVCGFNFNSFNMTLSPILEGHASQGSSAKQIYHFAQLQGNSAFQKYDYGLILNKIRYQSIFPPLYNLSLALGKVALHRGDGDWLGSESDVLRLERDLPNCIENRNIRFEGFSHFDFTISKDVRSLVYDRVISLCGSNR", "length": 457 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" }, { "id": "RGD:708441", "url": "https://alliancegenome.org/gene/RGD:708441#orthology", "database": "AGR" }, { "id": "MGI:2679259", "url": "https://alliancegenome.org/gene/MGI:2679259#orthology", "database": "AGR" }, { "id": "MGI:1926003", "url": "https://alliancegenome.org/gene/MGI:1926003#orthology", "database": "AGR" }, { "id": "MGI:3779637", "url": "https://alliancegenome.org/gene/MGI:3779637#orthology", "database": "AGR" }, { "id": "MGI:3647308", "url": "https://alliancegenome.org/gene/MGI:3647308#orthology", "database": "AGR" }, { "id": "MGI:3647649", "url": "https://alliancegenome.org/gene/MGI:3647649#orthology", "database": "AGR" }, { "id": "MGI:1917416", "url": "https://alliancegenome.org/gene/MGI:1917416#orthology", "database": "AGR" }, { "id": "MGI:1914967", "url": "https://alliancegenome.org/gene/MGI:1914967#orthology", "database": "AGR" }, { "id": "MGI:3644466", "url": "https://alliancegenome.org/gene/MGI:3644466#orthology", "database": "AGR" }, { "id": "MGI:96789", "url": "https://alliancegenome.org/gene/MGI:96789#orthology", "database": "AGR" }, { "id": "RGD:1304912", "url": "https://alliancegenome.org/gene/RGD:1304912#orthology", "database": "AGR" }, { "id": "RGD:1565682", "url": "https://alliancegenome.org/gene/RGD:1565682#orthology", "database": "AGR" }, { "id": "RGD:1309724", "url": "https://alliancegenome.org/gene/RGD:1309724#orthology", "database": "AGR" }, { "id": "RGD:3008", "url": "https://alliancegenome.org/gene/RGD:3008#orthology", "database": "AGR" }, { "id": "RGD:1560354", "url": "https://alliancegenome.org/gene/RGD:1560354#orthology", "database": "AGR" }, { "id": "RGD:2321667", "url": "https://alliancegenome.org/gene/RGD:2321667#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VKT1-1", "protein_name": "Partial AB-hydrolase lipase domain-containing protein", "gene_name": "CG17093", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MQLGFLYAFVALLAIFRVEPSEGIIDINNQLNNIISPPILPAVESILDINGDADSTEDEQKVRLQRESIVKDYGFVFKPQPIVLESNSSYKPSVESEGQAQSFSRGLEEAKLQIQKQSQSQSQAQGLGQSQQQIQYANIARTKVQKQFQSQQLGLAQSQQQTQIQQSLNQDGAKLREKPYPHIQTSSQRNADDPESEEAEAPGGLSGKIALVPPNEEGDQKQDQAQSQIEDEAEVLRQGLAQTESQIQNQRQGLEKEIQGQSQSQDQAQSQDEAINPESANAENRSSQQSGDVAENQDQAESQAQERSQLQLEGQEQSQDQAQSQDQSQALEKGGAPPLSPQQSLVQAEDQAQEDPIDQSLHQAQSEVLNQVKSQTNGQLKAQAQMQAQVLDQALEDAHVQYQSQAQSQGISLSQTTQQSLVEPDDQAKEDPVDQSLHQAQSEIIKQLLSQTNDQDKAQAQAQAQTLDQALEEAHVQYQSQTQAQGTPIFQPPQLQPEDRDQDTALDQSPTQAQLDAQSQSQEQANTKLQRKSQAQSEAHGIILTTLRKAQAQQQSEVQSPQQEPLRSDDQSGDQAGDVAQNTALDQSLHQAQAEVQEQLQSQTQASGTSLTQSQQQSQVQAVEALAQSLTQAHAQIQEQAQSQSQSQEQDQSQSQAPNERQSQLQSQRQDQDQGPKFDDDLDEQPAPRSCSQCQKASYPQYITEVDIEIDAKLDTPKMISKYGHQAETHYAFTADGYKLCLHRIPRSGATPVLLVHGLMASSDTWVQFGPSQGLAYILSQSGYDVWMLNTRGNVYSEERLAGRESDKIFWDFSFHEIGQYDLPAAIDLILLQTKMPSIQYIGHSQGSTAFFVMCSERPEYAGKISLMQSLSPSVYMEGTRSPALKFMKVLQGGFTMLLNLLGGHKISLKNRIVDMFRNHICNKLIPSRICAIFEFVVCGFNFNSFNMTLSPILEGHASQGSSAKQIYHFAQLQGNSAFQKYDYGLILNKIRYQSIFPPLYNLSLALGKVALHRGDGDWLGSESDVLRLERDLPNCIENRNIRFEGFSHFDFTISKDVRSLVYDRVIDLCGSN", "length": 1073 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VKT2-1", "protein_name": "AB hydrolase-1 domain-containing protein", "gene_name": "Dmel\\CG7329", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPHAICILVVLGIYTLDGSGVLGGFMENTYPASVIEDAHLNTIQLLEKYKHPAETHQVTTDDKYILTLHRIARPGAKPVLLVHGLEDTSSTWIVMGPESGLGYFLYANGYDVWMGNVRGNRYSKGHVKLNPNTDKSYWSFSWHEIGMYDLPAMIDGVLQKTGYQKLSYFGHSQGTTSFFVMASSRPEYNAKIHLMSALAPVAFMKHMKAPLMGIARMGMNMFGDNFELFPHSEVFLNQCLSSAAMLKTCMRFYWQIVGKNREEQNMTMFPVVLGHLPGGCNIKQALHYLQMQKSDRFCQYDYESKENQRLYGRSTPPDYRLERIKAPVALYYGSNDYLSAVEDVHRLAKVLPNVVENHLYRKWNHMDMIWGISARRSIQPRILQVMQYWETGGGGTKDGTTGSPVEEDVPQLTTETPIEEGTTQGDEKIGNVQGNEEQGHAEETEQVQVTTSPTSEL", "length": 457 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" }, { "id": "RGD:708441", "url": "https://alliancegenome.org/gene/RGD:708441#orthology", "database": "AGR" }, { "id": "MGI:2679259", "url": "https://alliancegenome.org/gene/MGI:2679259#orthology", "database": "AGR" }, { "id": "MGI:1926003", "url": "https://alliancegenome.org/gene/MGI:1926003#orthology", "database": "AGR" }, { "id": "MGI:3779637", "url": "https://alliancegenome.org/gene/MGI:3779637#orthology", "database": "AGR" }, { "id": "MGI:3647308", "url": "https://alliancegenome.org/gene/MGI:3647308#orthology", "database": "AGR" }, { "id": "MGI:3647649", "url": "https://alliancegenome.org/gene/MGI:3647649#orthology", "database": "AGR" }, { "id": "MGI:1917416", "url": "https://alliancegenome.org/gene/MGI:1917416#orthology", "database": "AGR" }, { "id": "MGI:1914967", "url": "https://alliancegenome.org/gene/MGI:1914967#orthology", "database": "AGR" }, { "id": "MGI:3644466", "url": "https://alliancegenome.org/gene/MGI:3644466#orthology", "database": "AGR" }, { "id": "MGI:96789", "url": "https://alliancegenome.org/gene/MGI:96789#orthology", "database": "AGR" }, { "id": "RGD:1304912", "url": "https://alliancegenome.org/gene/RGD:1304912#orthology", "database": "AGR" }, { "id": "RGD:1565682", "url": "https://alliancegenome.org/gene/RGD:1565682#orthology", "database": "AGR" }, { "id": "RGD:1309724", "url": "https://alliancegenome.org/gene/RGD:1309724#orthology", "database": "AGR" }, { "id": "RGD:3008", "url": "https://alliancegenome.org/gene/RGD:3008#orthology", "database": "AGR" }, { "id": "RGD:1560354", "url": "https://alliancegenome.org/gene/RGD:1560354#orthology", "database": "AGR" }, { "id": "RGD:2321667", "url": "https://alliancegenome.org/gene/RGD:2321667#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VKT7-1", "protein_name": "Lipase", "gene_name": "Dmel\\CG18302", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLKSCHLNYCYGILISLFIFCDTASGDLIKVDKTILEDANLITPDLIKKYGYPAETHKIQAKDGFVLTAHRIPKPGGQPVLLVHGLLDSSVAYVILGPERSLGFLLSDMGYDVWLLNTRGNRYSRKHKRYHRYQPQFWDFSFHELGVYDLPAAIDYVLARSKDFEQIHYVGHSQGTTSFFVMGSERSAYMKKIKLMQALAPVVFWDYIDSPIILTFVKYLRPLVFIARSFGIYEFPPENEVWRSLIHKICSFVFQNTCTYFLMEAMGVDYAQFNSSLLPLFTGHASSGSSVKSLEHYGQQIHSGGFFKYNYYSTWENRRNHGVDTPPQYKLTNVDCKVALYYSRNDRLTSDKDVVRLRDILPNVVLDYMFPDPLYNHINFIWGNDVKTVLNDRMIELMRKVDNGEV", "length": 406 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" }, { "id": "RGD:708441", "url": "https://alliancegenome.org/gene/RGD:708441#orthology", "database": "AGR" }, { "id": "MGI:2679259", "url": "https://alliancegenome.org/gene/MGI:2679259#orthology", "database": "AGR" }, { "id": "MGI:1926003", "url": "https://alliancegenome.org/gene/MGI:1926003#orthology", "database": "AGR" }, { "id": "MGI:3779637", "url": "https://alliancegenome.org/gene/MGI:3779637#orthology", "database": "AGR" }, { "id": "MGI:3647308", "url": "https://alliancegenome.org/gene/MGI:3647308#orthology", "database": "AGR" }, { "id": "MGI:3647649", "url": "https://alliancegenome.org/gene/MGI:3647649#orthology", "database": "AGR" }, { "id": "MGI:1917416", "url": "https://alliancegenome.org/gene/MGI:1917416#orthology", "database": "AGR" }, { "id": "MGI:1914967", "url": "https://alliancegenome.org/gene/MGI:1914967#orthology", "database": "AGR" }, { "id": "MGI:3644466", "url": "https://alliancegenome.org/gene/MGI:3644466#orthology", "database": "AGR" }, { "id": "MGI:96789", "url": "https://alliancegenome.org/gene/MGI:96789#orthology", "database": "AGR" }, { "id": "RGD:1304912", "url": "https://alliancegenome.org/gene/RGD:1304912#orthology", "database": "AGR" }, { "id": "RGD:1565682", "url": "https://alliancegenome.org/gene/RGD:1565682#orthology", "database": "AGR" }, { "id": "RGD:1309724", "url": "https://alliancegenome.org/gene/RGD:1309724#orthology", "database": "AGR" }, { "id": "RGD:3008", "url": "https://alliancegenome.org/gene/RGD:3008#orthology", "database": "AGR" }, { "id": "RGD:1560354", "url": "https://alliancegenome.org/gene/RGD:1560354#orthology", "database": "AGR" }, { "id": "RGD:2321667", "url": "https://alliancegenome.org/gene/RGD:2321667#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VKT8-1", "protein_name": "Lipase", "gene_name": "Dmel\\CG18301", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSLSSSSKFLIWTFFLGLFQLEANAFFNPFQLAIPSSVLEDAHLNTIQLISKYGYPAENYTVQSDDGYLLGLFRIARPGALPVLLVHGLMDSSDTWVMMGPSSSLGYMLYEQGYDVWMANVRGNTYTKRHVRYSAEDSDFWNFSFHEMGIFDLPAIIDYILMQSGFGQLHYIGHSQGSTIFWILASERPEYMEKIVMMQALAPVAFLSHCRSPIVNLLASQDTAVASFLSAAGYNEFLPSNSVIDQFKRYACRDIISSSVCQSLFFILFGFNGQQVNQTMLPIVVGHTPAGASIRQMHHYGQLRNSGKFQQFDYGLLNFLHYGSLSPPPYELEKVKAKVAIYYAKNDWIAPPEDVDMLFNRLPNVVEKYLVPNENFNHFDLVWGRDAKRILWNRMLGVMQSVVPYSSYNDGDSITTVFVNRF", "length": 422 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" }, { "id": "RGD:708441", "url": "https://alliancegenome.org/gene/RGD:708441#orthology", "database": "AGR" }, { "id": "MGI:2679259", "url": "https://alliancegenome.org/gene/MGI:2679259#orthology", "database": "AGR" }, { "id": "MGI:1926003", "url": "https://alliancegenome.org/gene/MGI:1926003#orthology", "database": "AGR" }, { "id": "MGI:3779637", "url": "https://alliancegenome.org/gene/MGI:3779637#orthology", "database": "AGR" }, { "id": "MGI:3647308", "url": "https://alliancegenome.org/gene/MGI:3647308#orthology", "database": "AGR" }, { "id": "MGI:3647649", "url": "https://alliancegenome.org/gene/MGI:3647649#orthology", "database": "AGR" }, { "id": "MGI:1917416", "url": "https://alliancegenome.org/gene/MGI:1917416#orthology", "database": "AGR" }, { "id": "MGI:1914967", "url": "https://alliancegenome.org/gene/MGI:1914967#orthology", "database": "AGR" }, { "id": "MGI:3644466", "url": "https://alliancegenome.org/gene/MGI:3644466#orthology", "database": "AGR" }, { "id": "MGI:96789", "url": "https://alliancegenome.org/gene/MGI:96789#orthology", "database": "AGR" }, { "id": "RGD:1304912", "url": "https://alliancegenome.org/gene/RGD:1304912#orthology", "database": "AGR" }, { "id": "RGD:1565682", "url": "https://alliancegenome.org/gene/RGD:1565682#orthology", "database": "AGR" }, { "id": "RGD:1309724", "url": "https://alliancegenome.org/gene/RGD:1309724#orthology", "database": "AGR" }, { "id": "RGD:3008", "url": "https://alliancegenome.org/gene/RGD:3008#orthology", "database": "AGR" }, { "id": "RGD:1560354", "url": "https://alliancegenome.org/gene/RGD:1560354#orthology", "database": "AGR" }, { "id": "RGD:2321667", "url": "https://alliancegenome.org/gene/RGD:2321667#orthology", "database": "AGR" }, { "id": "SGD:S000001623", "url": "https://alliancegenome.org/gene/SGD:S000001623#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VPE9-1", "protein_name": "Lipase", "gene_name": "mag", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNPIFCALLFSLVAGLVLAEKSDYCLSEIVKSDERIRSHGYPTETHEVTTQDGYVLTLFRIPYSHKLKNQNEKRPPILLQHGLFSNSDCWLSSGPDNSLAYLLADAGYDVWLGNARGNIYSRNNIIISLNSHKFWHFDWHEIGTIDIPAMIDYILADTGFDQIHYAGHSQGTTVYLVMLSERPEYNALIKSGHLLAPCAFFEHGTSFIFNALGPLVGTPGGIWNQLLVDTELIPNNNLVNRLVDNSCHLSNTICNNAFIMFANGGYVNANASSMSVLIETHPAGSSSNQGIHYLQLWKSLKFRQYDWGTKKNNELYGQDLPPDYDLSKIVAPTHLYSSTNDALCGPEDVNTLVENFPHLTEDYRVPVQSFNHLDFIIAKNMKELVNDPIIERINSYEGR", "length": 399 }, "evidence": [ { "id": "HGNC:23444", "url": "https://alliancegenome.org/gene/HGNC:23444#orthology", "database": "AGR" }, { "id": "RGD:708441", "url": "https://alliancegenome.org/gene/RGD:708441#orthology", "database": "AGR" }, { "id": "MGI:2679259", "url": "https://alliancegenome.org/gene/MGI:2679259#orthology", "database": "AGR" }, { "id": "MGI:1926003", "url": "https://alliancegenome.org/gene/MGI:1926003#orthology", "database": "AGR" }, { "id": "MGI:3779637", "url": "https://alliancegenome.org/gene/MGI:3779637#orthology", "database": "AGR" }, { "id": "MGI:3647308", "url": 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"categories": [ "3D Structure" ] }, { "id": "8B9Z", "url": "https://www.rcsb.org/structure/8B9Z", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8BA0", "url": "https://www.rcsb.org/structure/8BA0", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ESW", "url": "https://www.rcsb.org/structure/8ESW", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ESZ", "url": "https://www.rcsb.org/structure/8ESZ", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF10249", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10249", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-611105", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-611105", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-6799198", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6799198", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_651972", "url": 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"MPEPRSPMASFAESVLNVIDGPITWFRESIVEPNQQKQNWYHQRFRRVPTIDQCYTDDAVCRFEADQQFRRDRMVDNEIVNILRQRFEDCTLYEAPDHMVKCRPLMDQYEKATENWFIKYGDLGGYANAKTAYMKQKHRLIWERRHGPVGSGMKEEAAH", "length": 159, "header": "tr|Q9VQR2-1|Q9VQR2_DROME Isoform 1 of NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 OS=Drosophila melanogaster OX=7227 GN=ND-PDSW PE=1 SV=1 CANONICAL=Q9VQR2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VQR2", "url": "https://www.uniprot.org/uniprotkb/Q9VQR2" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VQR2", "url": "https://www.uniprot.org/uniprotkb/Q9VQR2" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQR2", "url": "https://www.uniprot.org/uniprotkb/Q9VQR2" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQR2", "url": "https://www.uniprot.org/uniprotkb/Q9VQR2" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VQR2", "url": "https://www.uniprot.org/uniprotkb/Q9VQR2" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VQR2", "url": "https://www.uniprot.org/uniprotkb/Q9VQR2" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VQR2", "url": "https://www.uniprot.org/uniprotkb/Q9VQR2" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQR2", "url": "https://www.uniprot.org/uniprotkb/Q9VQR2" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQR2", "url": "https://www.uniprot.org/uniprotkb/Q9VQR2" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"title": "Cryo-EM structures of mitochondrial respiratory complex I from Drosophila melanogaster.", "journal": "Elife", "date": "2023", "authors": "Agip Ahmed-Noor A, Chung Injae, Sanchez-Martinez Alvaro, Whitworth Alexander J, Hirst Judy", "evidence": [ { "database": "UniProtKB", "id": "Q9VQR2", "url": "https://www.uniprot.org/uniprotkb/Q9VQR2" } ], "reference": [ { "type": "PubMed", "id": "36622099", "url": "https://glygen.org/publication/PubMed/36622099" } ] }, { "title": "Resting mitochondrial complex I from Drosophila melanogaster adopts a helix-locked state.", "journal": "Elife", "date": "2023", "authors": "Padavannil Abhilash, Murari Anjaneyulu, Rhooms Shauna-Kay, Owusu-Ansah Edward, Letts James A", "evidence": [ { "database": "UniProtKB", "id": "Q9VQR2", "url": "https://www.uniprot.org/uniprotkb/Q9VQR2" } ], "reference": [ { "type": "PubMed", "id": "36952377", "url": "https://glygen.org/publication/PubMed/36952377" } ] } ], "pathway": [ { "id": "dme:Dmel_CG8844", "name": "", 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"name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "Q9VQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQS0/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_608787", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608787" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VQS0", "url": "https://www.uniprot.org/uniprotkb/Q9VQS0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "bs30c03.y1", "url": "https://www.uniprot.org/uniprotkb/Q9VQS0", "locus": { "chromosome": "2L", "start_pos": 3517273, "end_pos": 3519651, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0031545", "url": "https://www.ensemblgenomes.org/id/FBgn0031545" } ] } } ], "crossref": [ { "id": "FB:FBgn0031545", "url": "https://alliancegenome.org/gene/FB:FBgn0031545", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0031545", "url": "https://bgee.org/?page=gene&gene_id=FBgn0031545", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0031545", "url": "https://flybase.org/reports/FBgn0031545", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "33574", "url": "https://www.ncbi.nlm.nih.gov/gene/33574", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VQS0", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VQS0*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR026099", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026099", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG3213", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3213", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HYKELPM", "url": "https://omabrowser.org/oma/group/HYKELPM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VQS0", "url": "https://www.orthodb.org/?gene=Q9VQS0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23162", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23162", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23162:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23162:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "NP_608787", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608787", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VQS0", "url": "https://www.uniprot.org/uniprotkb/Q9VQS0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VQS0-1", "url": "https://www.uniprot.org/uniprotkb/Q9VQS0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAENTEYTDEGGEYEDDENQYLGEQHMMEEGPDEDLFSKLGESSDDPEQKRMYMEYLALIKEIDCQNKIIQDIKSNIMDMCAKPCKTRNELREIKRLRICMEQENIKLHTMMNRAVQLQNFGSHRHYKELAMTTTVDEDNLSPYMCGIGPCAPAGSATDPCSEEPSSCASVCGGGGGGGGQRDMAGQDDKLICALQKAMQKMKGACPEDKKMIEEIACAIMSCKKQPVCVPGPCPPPPCPGPCQGPCPESSSSSIAPCPPPCPAKRKAQKAPCPQPQPQPPGKCESLEKLKRRIQCMQTSVKKLLQEVSNRDASEPCDVDDDDDEGEEDPCSRPCPPRPPCPEDPDPLVICGGKRNTKADKYEKMKENYTRLLTEFQRKDCQMKEMQKRMKGICGPCPSKGGDGDADAAELNLLRARVNELKEEQLEFKCIMKEQSQQLEDYRNKYLLAQQKVEEQCVSLEKLNMNNKRIEQQINTEVKEIRAKFQEKLNELLHFPKLLENEQLKLAQVCKEKDEMQTKLVVVCKELKACKTQMEQQPNVDVRPQLAQCQMELTQARNELEELLRQRDLFCEQLKSTQDDLDTLRTESAKIIAGTKERAELIKSQQQEQINRLEKELAQCRATASLSVNDREAVIREMQGQLNTLSYSFDAAQKQIKTLRNHIAYVSNENCFPVKC", "length": 676, "header": "tr|Q9VQS0-1|Q9VQS0_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=bs30c03.y1 PE=1 SV=1 CANONICAL=Q9VQS0-1" }, "isoforms": [ { "isoform_ac": "Q9VQS0-1", "url": "https://www.uniprot.org/uniprotkb/Q9VQS0/entry#Q9VQS0-1", "sequence": { "sequence": "MAENTEYTDEGGEYEDDENQYLGEQHMMEEGPDEDLFSKLGESSDDPEQKRMYMEYLALIKEIDCQNKIIQDIKSNIMDMCAKPCKTRNELREIKRLRICMEQENIKLHTMMNRAVQLQNFGSHRHYKELAMTTTVDEDNLSPYMCGIGPCAPAGSATDPCSEEPSSCASVCGGGGGGGGQRDMAGQDDKLICALQKAMQKMKGACPEDKKMIEEIACAIMSCKKQPVCVPGPCPPPPCPGPCQGPCPESSSSSIAPCPPPCPAKRKAQKAPCPQPQPQPPGKCESLEKLKRRIQCMQTSVKKLLQEVSNRDASEPCDVDDDDDEGEEDPCSRPCPPRPPCPEDPDPLVICGGKRNTKADKYEKMKENYTRLLTEFQRKDCQMKEMQKRMKGICGPCPSKGGDGDADAAELNLLRARVNELKEEQLEFKCIMKEQSQQLEDYRNKYLLAQQKVEEQCVSLEKLNMNNKRIEQQINTEVKEIRAKFQEKLNELLHFPKLLENEQLKLAQVCKEKDEMQTKLVVVCKELKACKTQMEQQPNVDVRPQLAQCQMELTQARNELEELLRQRDLFCEQLKSTQDDLDTLRTESAKIIAGTKERAELIKSQQQEQINRLEKELAQCRATASLSVNDREAVIREMQGQLNTLSYSFDAAQKQIKTLRNHIAYVSNENCFPVKC", "length": 676, "header": "tr|Q9VQS0-1|Q9VQS0_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=bs30c03.y1 PE=1 SV=1 CANONICAL=Q9VQS0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VQS0", "url": "https://www.uniprot.org/uniprotkb/Q9VQS0" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VQS0", "url": "https://www.uniprot.org/uniprotkb/Q9VQS0" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQS0", "url": "https://www.uniprot.org/uniprotkb/Q9VQS0" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQS0", "url": "https://www.uniprot.org/uniprotkb/Q9VQS0" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VQS0", "url": "https://www.uniprot.org/uniprotkb/Q9VQS0" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VQS0", "url": "https://www.uniprot.org/uniprotkb/Q9VQS0" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VQS0", "url": "https://www.uniprot.org/uniprotkb/Q9VQS0" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQS0", "url": "https://www.uniprot.org/uniprotkb/Q9VQS0" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQS0", "url": "https://www.uniprot.org/uniprotkb/Q9VQS0" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VQT6", "url": "https://www.uniprot.org/uniprotkb/Q9VQT6" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu 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The cardinal anatomic changes of the valve include leaflet thickening, commissural fusion, and shortening and thickening of the tendinous cords." }, "synonyms": [ { "id": "DOID:0050827", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050827", "name": "rheumatic carditis", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "0050827", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050827" } ] }, { "disease_id": "DOID:0060071", "recommended_name": { "id": "DOID:0060071", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0060071", "name": "pre-malignant neoplasm", "description": "A disease of cellular proliferation that results in abnormal growths in the body, which do not invade or destroy the surrounding tissue but, given enough time, will transform into a cancer." }, "synonyms": [], "unlinked_id_list": [ "DOID:9108" ], "evidence": [ { "id": "0060071", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060071" } ] }, { "disease_id": "DOID:0080599", "recommended_name": { "id": "DOID:0080599", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080599", "name": "Coronavirus infectious disease", "description": "A viral infectious disease that has_material_basis_in Coronavirus." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "0080599", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080599" } ] }, { "disease_id": "DOID:11335", "recommended_name": { "id": "DOID:11335", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11335", "name": "sarcoidosis", "description": "A hypersensitivity reaction type IV disease characterized by the growth of collections of inflammatory cells (granulomas) in multiple organs." }, "synonyms": [ { "id": "DOID:11335", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11335", "name": "Boeck sarcoid", "description": "" }, { "id": "DOID:11335", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11335", "name": "lymphogranulomatosis", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "11335", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11335" } ] }, { "disease_id": "DOID:11394", "recommended_name": { "id": "DOID:11394", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11394", "name": "adult respiratory distress syndrome", "description": "A respiratory failure that results from diffuse injury to the endothelium of the lung (as in sepsis, chest trauma, massive blood transfusion, aspiration of the gastric contents, or pneumonia) and is characterized by pulmonary edema with an abnormally high amount of protein in the edematous fluid and by difficult rapid breathing and hypoxemia." }, "synonyms": [ { "id": "DOID:11394", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11394", "name": "ARDS", "description": "" }, { "id": "DOID:11394", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11394", "name": "Non-cardiogenic pulmonary edema", "description": "" }, { "id": "DOID:11394", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11394", "name": "Shock lung", "description": "" }, { "id": "DOID:11394", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11394", "name": "adult RDS", "description": "" }, { "id": "DOID:11394", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11394", "name": "acute respiratory distress syndrome", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "11394", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11394" } ] }, { "disease_id": "DOID:11650", "recommended_name": { "id": "DOID:11650", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11650", "name": "bronchopulmonary dysplasia", "description": "A lung disease that is characterized by underdeveloped lungs in newborns that can be easily irritated or inflamed after birth resulting in damage to the alveoli of the lungs and bronchi. Most newborns who develop BPD are born more than 10 weeks before their due dates, weigh less than 2 pounds at birth, and have breathing problems." }, "synonyms": [ { "id": "DOID:11650", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11650", "name": "Perinatal bronchopulmonary dysplasia", "description": "" }, { "id": "DOID:11650", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11650", "name": "neonatal chronic respiratory disease", "description": "" }, { "id": "DOID:11650", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11650", "name": "Bronchopulmonary dysplasia of newborn", "description": "" }, { "id": "DOID:11650", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11650", "name": "Chronic lung disease of prematurity", "description": "" }, { "id": "DOID:11650", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11650", "name": "Neonatal chronic lung disease", "description": "" }, { "id": "DOID:11650", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11650", "name": "Respiratory insufficiency", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "11650", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11650" } ] }, { "disease_id": "DOID:12120", "recommended_name": { "id": "DOID:12120", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12120", "name": "pulmonary alveolar proteinosis", "description": "A lung disease that is characterized by abnormal accumulation of surfactant occurs within the alveoli, interfering with gas exchange." }, "synonyms": [ { "id": "MONDO:0009929", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009929", "name": "surfactant metabolism dysfunction, pulmonary, 1", "description": "" }, { "id": "MONDO:0009929", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009929", "name": "SMDP1", "description": "" }, { "id": "MONDO:0009929", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009929", "name": "interstitial lung disease due to SP-B dysfunction", "description": "" }, { "id": "MONDO:0009929", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009929", "name": "interstitial lung disease due to surfactant Protein B deficiency", "description": "" }, { "id": "MONDO:0009929", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009929", "name": "neonatal acute respiratory distress due to SP-B deficiency", "description": "" }, { "id": "MONDO:0009929", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009929", "name": "neonatal acute respiratory distress due to surfactant protein B deficiency", "description": "" }, { "id": "MONDO:0009929", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009929", "name": "pulmonary alveolar proteinosis, congenital, 1", "description": "" }, { "id": "MONDO:0009929", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009929", "name": "surfactant metabolism dysfunction, pulmonary, 1", "description": "" }, { "id": "MONDO:0009929", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009929", "name": "surfactant metabolism dysfunction, pulmonary, type 1", "description": "" }, { "id": "MONDO:0009929", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009929", "name": "pulmonary surfactant protein B, deficiency of", "description": "" }, { "id": "MONDO:0010424", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010424", "name": "surfactant metabolism dysfunction, pulmonary, 4", "description": "" }, { "id": "MONDO:0010424", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010424", "name": "surfactant metabolism dysfunction, pulmonary, 4", "description": "" }, { "id": "MONDO:0010424", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010424", "name": "surfactant metabolism dysfunction, pulmonary, type 4", "description": "" }, { "id": "MONDO:0010424", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010424", "name": "SMDP4", "description": "" }, { "id": "MONDO:0012582", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012582", "name": "interstitial lung disease due to ABCA3 deficiency", "description": "Interstitial lung disease due to ABCA3 deficiency is a rare genetic respiratory disease characterized by a variable clinical outcome ranging from a fatal respiratory distress syndrome in the neonatal period to chronic interstitial lung disease developing in infancy or childhood with chronic cough, rapid breathing, shortness of breath and recurrent pulmonary infections. Clinical manifestations of respiratory failure include grunting, intercostal retractions, nasal flaring, cyanosis, and progressive dyspnea." }, { "id": "MONDO:0012582", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012582", "name": "interstitial lung disease due to ABCA3 deficiency", "description": "" }, { "id": "MONDO:0012582", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012582", "name": "interstitial lung disease due to ATP-binding cassette subfamily A member 3 deficiency", "description": "" }, { "id": "MONDO:0012582", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012582", "name": "surfactant metabolism dysfunction, pulmonary, type 3", "description": "" }, { "id": "MONDO:0012582", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012582", "name": "SMDP3", "description": "" }, { "id": "MONDO:0012582", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012582", "name": "surfactant metabolism dysfunction, pulmonary, 3", "description": "" }, { "id": "MONDO:0013712", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013712", "name": "surfactant metabolism dysfunction, pulmonary, 5", "description": "Any hereditary pulmonary alveolar proteinosis in which the cause of the disease is a mutation in the CSF2RB gene." }, { "id": "MONDO:0013712", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013712", "name": "CSF2RB hereditary pulmonary alveolar proteinosis", "description": "" }, { "id": "MONDO:0013712", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013712", "name": "hereditary pulmonary alveolar proteinosis caused by mutation in CSF2RB", "description": "" }, { "id": "MONDO:0013712", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013712", "name": "surfactant metabolism dysfunction, pulmonary, 5", "description": "" }, { "id": "MONDO:0013712", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013712", "name": "surfactant metabolism dysfunction, pulmonary, type 5", "description": "" }, { "id": "MONDO:0013712", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013712", "name": "SMDP5", "description": "" }, { "id": "MONDO:0024465", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024465", "name": "surfactant metabolism dysfunction, pulmonary, 2", "description": "" }, { "id": "MONDO:0024465", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024465", "name": "SMDP2", "description": "" }, { "id": "MONDO:0024465", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024465", "name": "desquamative interstitial pneumonitis due to surfactant Protein C deficiency", "description": "" }, { "id": "MONDO:0024465", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024465", "name": "interstitial lung disease due to surfactant Protein C deficiency", "description": "" }, { "id": "MONDO:0024465", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024465", "name": "pulmonary alveolar proteinosis, congenital, 2", "description": "" }, { "id": "MONDO:0024465", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024465", "name": "surfactant metabolism dysfunction, pulmonary, 2", "description": "" }, { "id": "MIM:265120", "resource": "MIM", "url": "https://www.omim.org/entry/265120", "name": "Pulmonary surfactant metabolism dysfunction 1", "description": "Pulmonary surfactant metabolism dysfunction 1" }, { "id": "MIM:300770", "resource": "MIM", "url": "https://www.omim.org/entry/300770", "name": "Pulmonary surfactant metabolism dysfunction 4", "description": "Pulmonary surfactant metabolism dysfunction 4" }, { "id": "MIM:610921", "resource": "MIM", "url": "https://www.omim.org/entry/610921", "name": "Pulmonary surfactant metabolism dysfunction 3", "description": "Pulmonary surfactant metabolism dysfunction 3" }, { "id": "MIM:614370", "resource": "MIM", "url": "https://www.omim.org/entry/614370", "name": "Pulmonary surfactant metabolism dysfunction 5", "description": "Pulmonary surfactant metabolism dysfunction 5" }, { "id": "MIM:610913", "resource": "MIM", "url": "https://www.omim.org/entry/610913", "name": "Pulmonary surfactant metabolism dysfunction 2", "description": "Pulmonary surfactant metabolism dysfunction 2" } ], "unlinked_id_list": [], "evidence": [ { "id": "12120", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12120" } ] }, { "disease_id": "DOID:12205", "recommended_name": { "id": "DOID:12205", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12205", "name": "dengue disease", "description": "A viral infectious disease that results in infection, has_material_basis_in Dengue virus (Orthoflavivirus denguei), which are transmitted by Aedes mosquito bite. The infection has symptom fever, has symptom severe headache, has symptom severe pain behind the eyes, has symptom joint pain, has symptom muscle and bone pain, has symptom rash, and has symptom mild bleeding." }, "synonyms": [ { "id": "DOID:12205", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12205", "name": "Dengue Fever", "description": "" }, { "id": "DOID:12205", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12205", "name": "breakbone fever", "description": "" }, { "id": "DOID:12205", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12205", "name": "classic dengue", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "12205", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12205" } ] }, { "disease_id": "DOID:12206", "recommended_name": { "id": "DOID:12206", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12206", "name": "dengue hemorrhagic fever", "description": "A dengue disease that occurs when a person experiences a second infection with a heterologous Dengue virus (Orthoflavivirus denguei) serotype, which is transmitted_by Aedes mosquito bite. The infection has_symptom hemorrhagic lesions of the skin, has_symptom thrombocytopenia, has_symptom reduction in the fluid part of the blood, and has_symptom high fever. Four distinct Dengue virus serotypes have been identified." }, "synonyms": [ { "id": "DOID:12206", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12206", "name": "DHF", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "12206", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12206" } ] }, { "disease_id": "DOID:12716", "recommended_name": { "id": "DOID:12716", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12716", "name": "newborn respiratory distress syndrome", "description": "A respiratory failure that is characterized by deficiency of the surfactant coating the inner surface of the lungs, by failure of the lungs to expand and contract properly during breathing with resulting collapse, and by the accumulation of a protein-containing film lining the alveoli and their ducts." }, "synonyms": [ { "id": "DOID:12716", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12716", "name": "HMD - Hyaline membrane disease", "description": "" }, { "id": "DOID:12716", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12716", "name": "Neonatal respiratory Distress syndrome", "description": "" }, { "id": "DOID:12716", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12716", "name": "hyaline membrane disease", "description": "" }, { "id": "DOID:12716", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12716", "name": "pulmonary hyaline membrane disease", "description": "" }, { "id": "DOID:12716", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12716", "name": "pulmonary hypoperfusion syndrome of newborn", "description": "" }, { "id": "DOID:12716", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12716", "name": "respiratory distress syndrome of newborn", "description": "" }, { "id": "MONDO:0009971", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009971", "name": "respiratory distress syndrome in premature infants", "description": "Infant acute respiratory distress syndrome is a lung disorder that affects premature infants caused by developmental insufficiency of surfactant production and structural immaturity of the lungs. The symptoms usually appear shortly after birth and may include tachypnea, tachycardia, chest wall retractions (recession), expiratory grunting, nasal flaring and cyanosis during breathing efforts." }, { "id": "MONDO:0009971", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009971", "name": "RDS", "description": "" }, { "id": "MONDO:0009971", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009971", "name": "respiratory distress syndrome", "description": "" }, { "id": "MONDO:0009971", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009971", "name": "RDS of prematurity", "description": "" }, { "id": "MONDO:0009971", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009971", "name": "Respiratory Distress Syndrome, Infant", "description": "" }, { "id": "MONDO:0009971", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009971", "name": "respiratory distress syndrome in premature infants", "description": "" }, { "id": "MONDO:0009971", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009971", "name": "IRDS", "description": "" }, { "id": "MONDO:0009971", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009971", "name": "NRDS", "description": "" }, { "id": "MONDO:0009971", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009971", "name": "RDS - infants", "description": "" }, { "id": "MONDO:0009971", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009971", "name": "hyaline Membrane disease", "description": "" }, { "id": "MONDO:0009971", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009971", "name": "infantile respiratory distress syndrome", "description": "" }, { "id": "MONDO:0009971", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009971", "name": "respiratory distress syndrome, infant", "description": "" }, { "id": "MIM:267450", "resource": "MIM", "url": "https://www.omim.org/entry/267450", "name": "Respiratory distress syndrome in premature infants", "description": "Respiratory distress syndrome in premature infants" } ], "unlinked_id_list": [], "evidence": [ { "id": "12716", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12716" } ] }, { "disease_id": "DOID:1273", "recommended_name": { "id": "DOID:1273", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1273", "name": "respiratory syncytial virus infectious disease", "description": "A viral infectious disease that results_in infection located_in upper respiratory tract or located_in lower respiratory tract, has_material_basis_in Human respiratory syncytial virus (Orthopneumovirus hominis), which is transmitted_by droplet spread of nasal secretions from an infected person while coughing or sneezing, or transmitted_by contaminated fomites. The infection has_symptom runny nose, has_symptom fever, has_symptom cough, has_symptom wheezing, and has_symptom respiratory distress." }, "synonyms": [ { "id": "DOID:1273", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1273", "name": "RSV", "description": "" }, { "id": "DOID:1273", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1273", "name": "respiratory syncytial virus", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "1273", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1273" } ] }, { "disease_id": "DOID:13564", "recommended_name": { "id": "DOID:13564", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13564", "name": "aspergillosis", "description": "An opportunistic mycosis that involves a spectrum of diseases of humans and animals caused by members of the genus Aspergillus infecting lungs, brain, kidney, heart, bone, eyes, sinuses, skin and gastrointestinal tract. It is a serious illnesses in people with a weakened immune system." }, "synonyms": [ { "id": "DOID:13564", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13564", "name": "Infection due to Aspergillus", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "13564", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13564" } ] }, { "disease_id": "DOID:1485", "recommended_name": { "id": "DOID:1485", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1485", "name": "cystic fibrosis", "description": "A syndrome that is characterized by the buildup of thick, sticky mucus that can damage many organs." }, "synonyms": [ { "id": "DOID:1485", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1485", "name": "CF", "description": "" }, { "id": "DOID:1485", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1485", "name": "mucoviscidosis", "description": "" }, { "id": "MONDO:0009061", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009061", "name": "cystic fibrosis", "description": "Autosomal recessive disorder caused by pathogenic variants in the CFTR gene (cystic fibrosis transmembrane conductance regulator), which encodes a chloride and bicarbonate channel expressed in epithelial cells, and follow the diagnosis criteria. Diagnosis requires evidence of CFTR dysfunction, defined as a sweat chloride concentration of 60 mmol/L or greater, or identification of two CF-causing CFTR pathogenic variants, or an abnormal nasal potential difference measurement. CF is a progressive, multi-organ disease characterized by chronic obstructive lung disease with recurrent infections, exocrine pancreatic insufficiency, intestinal obstruction (including meconium ileus in neonates), male infertility due to obstructive azoospermia, hepatobiliary complications, and elevated sweat chloride concentrations." }, { "id": "MONDO:0009061", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009061", "name": "CF", "description": "" }, { "id": "MONDO:0009061", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009061", "name": "cystic fibrosis", "description": "" }, { "id": "MONDO:0009061", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009061", "name": "cystic fibrosis lung disease, modifier of", "description": "" }, { "id": "MONDO:0009061", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009061", "name": "mucoviscidosis", "description": "" }, { "id": "MONDO:0009061", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009061", "name": "pseudomonas aeruginosa, susceptibility to chronic infection by, in cystic fibrosis", "description": "" }, { "id": "MONDO:0009061", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009061", "name": "fibrocystic disease of the pancreas", "description": "" }, { "id": "MIM:219700", "resource": "MIM", "url": "https://www.omim.org/entry/219700", "name": "Cystic fibrosis", "description": "Cystic fibrosis" } ], "unlinked_id_list": [], "evidence": [ { "id": "1485", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1485" } ] }, { "disease_id": "DOID:2799", "recommended_name": { "id": "DOID:2799", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2799", "name": "bronchiolitis obliterans", "description": "A obstructive lung disease involving obstruction of the bronchioles due to inflammation and fibrosis which occurs as a complication of various lung conditions or physiological insults." }, "synonyms": [ { "id": "DOID:2799", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2799", "name": "Bronchiolitis exudativa", "description": "" }, { "id": "DOID:2799", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2799", "name": "Bronchiolitis fibrosa obliterans", "description": "" }, { "id": "DOID:2799", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2799", "name": "Obliterative bronchiolitis", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "2799", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2799" } ] }, { "disease_id": "DOID:2841", "recommended_name": { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing." }, "synonyms": [ { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "bronchial hyperreactivity", "description": "" }, { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "chronic obstructive asthma", "description": "" }, { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "chronic obstructive asthma with acute exacerbation", "description": "" }, { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "chronic obstructive asthma with status asthmaticus", "description": "" }, { "id": "MONDO:0010940", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010940", "name": "inherited susceptibility to asthma", "description": "" }, { "id": "MONDO:0010940", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010940", "name": "asthma, nocturnal, susceptibility to", "description": "" }, { "id": "MIM:600807", "resource": "MIM", "url": "https://www.omim.org/entry/600807", "name": "Asthma", "description": "Asthma" } ], "unlinked_id_list": [ "DOID:0080811", "DOID:0080819" ], "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ] }, { "disease_id": "DOID:2957", "recommended_name": { "id": "DOID:2957", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2957", "name": "pulmonary tuberculosis", "description": "A tuberculosis that is a contagious disease located_in lungs. The infection has_symptom fever, has_symptom cough, has_symptom difficulty in breathing, has_symptom inflammatory infiltrations, has_symptom formation of tubercles, has_symptom caseation, has_symptom pleural effusion, and has_symptom fibrosis." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "2957", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2957" } ] }, { "disease_id": "DOID:3082", "recommended_name": { "id": "DOID:3082", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3082", "name": "interstitial lung disease", "description": "A lung disease that is characterized by inflammation and altered lung interstitium compromising pulmonary function and often has_symptom shortness of breath, dyspnea, and/or cough." }, "synonyms": [ { "id": "DOID:3082", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3082", "name": "ILD", "description": "" }, { "id": "MONDO:0030608", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0030608", "name": "interstitial lung disease 1", "description": "An interstitial lung disease in which the cause of the disease is a variation in the SFTPA1 gene." }, { "id": "MONDO:0030608", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0030608", "name": "ILD1", "description": "" }, { "id": "MONDO:0030608", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0030608", "name": "interstitial lung disease 1", "description": "" }, { "id": "MIM:619611", "resource": "MIM", "url": "https://www.omim.org/entry/619611", "name": "Interstitial lung disease 1", "description": "Interstitial lung disease 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "3082", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3082" } ] }, { "disease_id": "DOID:3083", "recommended_name": { "id": "DOID:3083", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3083", "name": "chronic obstructive pulmonary disease", "description": "An obstructive lung disease that is a chronic and progressive disorder of small airways in the lungs and that is characterized by irreversible airflow obstruction, typically identified by reductions in quantitative spirometric indices, induced forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (less than 0.7 is diagnostic of COPD). Lung volume is increased and pulmonary hypertension may occur. The pathologic changes result in the disruption of the airflow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough and chest tightness. COPD is a consequence (an end result) of chronic bronchitis, emphysema or both." }, "synonyms": [ { "id": "DOID:3083", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3083", "name": "COLD", "description": "" }, { "id": "DOID:3083", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3083", "name": "COPD", "description": "" }, { "id": "DOID:3083", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3083", "name": "chronic obstructive airway disease", "description": "" }, { "id": "DOID:3083", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3083", "name": "chronic obstructive lung disease", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "chronic obstructive pulmonary disease", "description": "A chronic and progressive lung disorder characterized by the loss of elasticity of the bronchial tree and the air sacs, destruction of the air sacs wall, thickening of the bronchial wall, and mucous accumulation in the bronchial tree. The pathologic changes result in the disruption of the air flow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough, and chest tightness. The two main types of chronic obstructive pulmonary disease are chronic obstructive bronchitis and emphysema." }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "COLD", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "COPD", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "COPD, chronic obstructive pulmonary disease", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "chronic obstructive airways disease", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "chronic obstructive lung disease", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "chronic obstructive pulmonary disease (COPD)", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "chronic obstructive pulmonary disease, (COPD)", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "cold", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "cold (chronic obstructive lung disease)", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "disease (COPD), chronic obstructive", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "obstructive lung disease, chronic", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "obstructive pulmonary disease (COPD), chronic", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "pulmonary disease (COPD), chronic obstructive", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "3083", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3083" } ] }, { "disease_id": "DOID:3908", "recommended_name": { "id": "DOID:3908", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma." }, "synonyms": [ { "id": "DOID:3908", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3908", "name": "NSCLC", "description": "" }, { "id": "DOID:3908", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3908", "name": "Non-small cell lung cancer", "description": "" }, { "id": "DOID:3908", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3908", "name": "non-small cell lung carcinoma", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ] }, { "disease_id": "DOID:399", "recommended_name": { "id": "DOID:399", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:399", "name": "tuberculosis", "description": "A primary bacterial infectious disease that is located_in lungs, located_in lymph nodes, located_in pericardium, located_in brain, located_in pleura or located_in gastrointestinal tract, has_material_basis_in Mycobacterium tuberculosis, which is transmitted_by droplets released into the air when an infected person coughs or sneezes." }, "synonyms": [], "unlinked_id_list": [ "DOID:2149" ], "evidence": [ { "id": "399", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:399" } ] }, { "disease_id": "DOID:4483", "recommended_name": { "id": "DOID:4483", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4483", "name": "rhinitis", "description": "A upper respiratory infectious disease which involves irritation and inflammation of the mucous membrane of the nose due to viruses, bacteria or irritants. The inflammation results in generation of excessive amounts of mucus leading to runny nose, as well as nasal congestion and post-nasal drip." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "4483", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4483" } ] }, { "disease_id": "DOID:526", "recommended_name": { "id": "DOID:526", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:526", "name": "human immunodeficiency virus infectious disease", "description": "A viral infectious disease that results in destruction of immune system, leading to life-threatening opportunistic infections and cancers, has_material_basis_in Human immunodeficiency virus 1 (Lentivirus humimdef1) or Human immunodeficiency virus 2 (Lentivirus humimdef2), which are transmitted by sexual contact, transmitted by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted by congenital method, and transmitted by contaminated needles. The virus infects helper T cells (CD4+ T cells) which are directly or indirectly destroyed, macrophages, and dendritic cells. The infection has symptom diarrhea, has symptom fatigue, has symptom fever, has symptom vaginal yeast infection, has symptom headache, has symptom mouth sores, has symptom muscle aches, has symptom sore throat, and has symptom swollen lymph glands." }, "synonyms": [ { "id": "DOID:526", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:526", "name": "HIV infection", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "526", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:526" } ] }, { "disease_id": "DOID:552", "recommended_name": { "id": "DOID:552", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:552", "name": "pneumonia", "description": "A lung disease that involves lung parenchyma or alveolar inflammation and abnormal alveolar filling with fluid (consolidation and exudation). It results from a variety of causes including infection with bacteria, viruses, fungi or parasites, and chemical or physical injury to the lungs. It is accompanied by fever, chills, cough, and difficulty in breathing." }, "synonyms": [ { "id": "DOID:552", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:552", "name": "acute pneumonia", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "552", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:552" } ] }, { "disease_id": "DOID:635", "recommended_name": { "id": "DOID:635", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:635", "name": "acquired immunodeficiency syndrome", "description": "A Human immunodeficiency virus infectious disease that results_in reduction in the numbers of CD4-bearing helper T cells below 200 per microliter of blood or 14% of all lymphocytes thereby rendering the subject highly vulnerable to life-threatening infections and cancers, has_material_basis_in Human immunodeficiency virus 1 (Lentivirus humimdef1) or Human immunodeficiency virus 2 (Lentivirus humimdef2), which are transmitted_by sexual contact, transmitted_by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted_by congenital method, and transmitted_by contaminated needles. Opportunistic infections are common in people with AIDS." }, "synonyms": [ { "id": "DOID:635", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:635", "name": "AIDS", "description": "" }, { "id": "DOID:635", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:635", "name": "acquired Immune deficiency", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "635", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:635" } ] }, { "disease_id": "DOID:6432", "recommended_name": { "id": "DOID:6432", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:6432", "name": "pulmonary hypertension", "description": "A hypertension characterized by an increase of blood pressure in the pulmonary artery, pulmonary vein or pulmonary capillaries." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "6432", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6432" } ] }, { "disease_id": "DOID:850", "recommended_name": { "id": "DOID:850", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:850", "name": "lung disease", "description": "A lower respiratory tract disease in which the function of the lungs is adversely affected by narrowing or blockage of the airways resulting in poor air flow, a loss of elasticity in the lungs that produces a decrease in the total volume of air that the lungs are able to hold, and clotting, scarring, or inflammation of the blood vessels that affect the ability of the lungs to take up oxygen and to release carbon dioxide." }, "synonyms": [], "unlinked_id_list": [ "DOID:9808", "DOID:4765", "DOID:60001", "DOID:3683" ], "evidence": [ { "id": "850", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:850" } ] }, { "disease_id": "DOID:874", "recommended_name": { "id": "DOID:874", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:874", "name": "bacterial pneumonia", "description": "A pneumonia involving inflammation of the lungs caused by bacteria." }, "synonyms": [ { "id": "DOID:874", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:874", "name": "Pneumonia due to other gram-negative bacteria", "description": "" }, { "id": "DOID:874", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:874", "name": "gram-negative pneumonia", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "874", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:874" } ] }, { "disease_id": "DOID:9074", "recommended_name": { "id": "DOID:9074", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9074", "name": "systemic lupus erythematosus", "description": "A lupus erythematosus that is an inflammation of connective tissue marked by skin rashes, joint pain and swelling, inflammation of the kidneys and inflammation of the tissue surrounding the heart." }, "synonyms": [ { "id": "DOID:9074", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9074", "name": "Lupus Erythematosus, systemic", "description": "" }, { "id": "DOID:9074", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9074", "name": "SLE - Lupus Erythematosus, systemic", "description": "" }, { "id": "DOID:9074", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9074", "name": "disseminated lupus erythematosus", "description": "" }, { "id": "MONDO:0007915", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007915", "name": "systemic lupus erythematosus", "description": "An autoimmune multi-organ disease typically associated with vasculopathy and autoantibody production. Most patients have antinuclear antibodies (ANA). The presence of anti-dsDNA or anti-Smith antibodies are highly-specific." }, { "id": "MONDO:0007915", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007915", "name": "Lupus", "description": "" }, { "id": "MONDO:0007915", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007915", "name": "SLE", "description": "" }, { "id": "MONDO:0007915", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007915", "name": "SLE - lupus erythematosus, systemic", "description": "" }, { "id": "MONDO:0007915", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007915", "name": "disseminated lupus erythematosus", "description": "" }, { "id": "MONDO:0007915", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007915", "name": "lupus erythematosus, systemic", "description": "" }, { "id": "MONDO:0007915", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007915", "name": "systemic lupus erythematosus", "description": "" }, { "id": "MONDO:0007915", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007915", "name": "systemic lupus erythematosus (disease)", "description": "" }, { "id": "MONDO:0007915", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007915", "name": "systemic lupus erythematosus susceptibility to", "description": "" }, { "id": "MONDO:0010433", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010433", "name": "systemic lupus erythematosus, susceptibility to, 15", "description": "" }, { "id": "MONDO:0010433", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010433", "name": "SLEB15", "description": "" }, { "id": "MONDO:0010433", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010433", "name": "systemic lupus erythematosus, susceptibility to, 15", "description": "" }, { "id": "MONDO:0011560", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011560", "name": "systemic lupus erythematosus, susceptibility to, 3", "description": "" }, { "id": "MONDO:0011560", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011560", "name": "SLEB3", "description": "" }, { "id": "MONDO:0011560", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011560", "name": "systemic lupus erythematosus, susceptibility to, 3", "description": "" }, { "id": "MONDO:0012036", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012036", "name": "systemic lupus erythematosus, susceptibility to, 4", "description": "" }, { "id": "MONDO:0012036", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012036", "name": "SLEB4", "description": "" }, { "id": "MONDO:0012036", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012036", "name": "systemic lupus erythematosus, susceptibility to, 4", "description": "" }, { "id": "MONDO:0012361", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012361", "name": "systemic lupus erythematosus, susceptibility to, 5", "description": "" }, { "id": "MONDO:0012361", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012361", "name": "SLEB5", "description": "" }, { "id": "MONDO:0012361", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012361", "name": "systemic lupus erythematosus, susceptibility to, 5", "description": "" }, { "id": "MONDO:0012369", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012369", "name": "systemic lupus erythematosus, susceptibility to, 6", "description": "" }, { "id": "MONDO:0012369", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012369", "name": "SLEB6", "description": "" }, { "id": "MONDO:0012369", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012369", "name": "systemic lupus erythematosus, susceptibility to, 6", "description": "" }, { "id": "MONDO:0012403", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012403", "name": "systemic lupus erythematosus, susceptibility to, 7", "description": "" }, { "id": "MONDO:0012403", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012403", "name": "SLEB7", "description": "" }, { "id": "MONDO:0012403", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012403", "name": "systemic lupus erythematosus, susceptibility to, 7", "description": "" }, { "id": "MONDO:0012404", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012404", "name": "systemic lupus erythematosus, susceptibility to, 8", "description": "" }, { "id": "MONDO:0012404", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012404", "name": "SLEB8", "description": "" }, { "id": "MONDO:0012404", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012404", "name": "systemic lupus erythematosus, susceptibility to, 8", "description": "" }, { "id": "MONDO:0012836", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012836", "name": "systemic lupus erythematosus, susceptibility to, 12", "description": "" }, { "id": "MONDO:0012836", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012836", "name": "SLEB12", "description": "" }, { "id": "MONDO:0012836", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012836", "name": "systemic lupus erythematosus, susceptibility to, 12", "description": "" }, { "id": "MONDO:0012884", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012884", "name": "systemic lupus erythematosus, susceptibility to, 13", "description": "" }, { "id": "MONDO:0012884", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012884", "name": "SLEB13", "description": "" }, { "id": "MONDO:0012884", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012884", "name": "systemic lupus erythematosus, susceptibility to, 13", "description": "" }, { "id": "MONDO:0013152", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013152", "name": "systemic lupus erythematosus, susceptibility to, 14", "description": "" }, { "id": "MONDO:0013152", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013152", "name": "SLEB14", "description": "" }, { "id": "MONDO:0013152", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013152", "name": "systemic lupus erythematosus, susceptibility to, 14", "description": "" }, { "id": "MONDO:0013743", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013743", "name": "autosomal systemic lupus erythematosus type 16", "description": "An instance of systemic lupus erythematosus (disease) that is caused by mutations in DNASE1L3." }, { "id": "MONDO:0013743", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013743", "name": "SLEB16", "description": "" }, { "id": "MONDO:0013743", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013743", "name": "systemic lupus erythematosus 16", "description": "" }, { "id": "MONDO:0013743", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013743", "name": "systemic lupus erythematosus related to DNASE1L3", "description": "" }, { "id": "MONDO:0013743", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013743", "name": "systemic lupus erythematosus type 16", "description": "" }, { "id": "MIM:152700", "resource": "MIM", "url": "https://www.omim.org/entry/152700", "name": "Systemic lupus erythematosus", "description": "Systemic lupus erythematosus" }, { "id": "MIM:609939", "resource": "MIM", "url": "https://www.omim.org/entry/609939", "name": "Systemic lupus erythematosus 6", "description": "Systemic lupus erythematosus 6" }, { "id": "MIM:614420", "resource": "MIM", "url": "https://www.omim.org/entry/614420", "name": "Systemic lupus erythematosus 16", "description": "Systemic lupus erythematosus 16" } ], "unlinked_id_list": [], "evidence": [ { "id": "9074", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9074" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VQU4", "url": "https://www.uniprot.org/uniprotkb/Q9VQU4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "lectin-24A", "url": "https://www.uniprot.org/uniprotkb/Q9VQU4", "locus": { "chromosome": "2L", "start_pos": 3716800, "end_pos": 3717773, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0040104", "url": "https://www.ensemblgenomes.org/id/FBgn0040104" } ] } } ], "crossref": [ { "id": "FB:FBgn0040104", "url": "https://alliancegenome.org/gene/FB:FBgn0040104", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0040104", "url": "https://bgee.org/?page=gene&gene_id=FBgn0040104", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00037", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00037", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0040104", "url": "https://flybase.org/reports/FBgn0040104", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "53543", "url": "https://www.ncbi.nlm.nih.gov/gene/53543", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001304", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001304", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051663", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051663", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG3410", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3410", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WNTCTEI", "url": "https://omabrowser.org/oma/group/WNTCTEI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VQU4", "url": "https://www.orthodb.org/?gene=Q9VQU4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22799", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22799", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22799:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22799:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00059", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00059", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_652637", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_652637", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VQU4", "url": "https://www.uniprot.org/uniprotkb/Q9VQU4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VQU4-1", "url": "https://www.uniprot.org/uniprotkb/Q9VQU4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFRLSVLVLNLLLVSHEFSAGTAKIEIQPLPALCNGYCFPTLKPVMEYVAIHQDKWNTCTEILANEARKDQIQLNIQLDALKADVSNIKASQLSKDEKLDRMEREQFAMHESLETINRYLTVKLDRTKLQLEAIKNTMDYMKAQMDGYFSAINGVQCLQPGFEKIGDRYFYIEEDVELNWLDAQAKCRRMGGHLASIKTKQEFDAIVEKLDDSKSYFLGVNENTKTGDFVSAASGKSCLYHEWGPGEPHHNNDQERCVSILRKLMHVGNCTYEKRFICQYGI", "length": 282, "header": "tr|Q9VQU4-1|Q9VQU4_DROME Isoform 1 of Lectin-24A OS=Drosophila melanogaster OX=7227 GN=lectin-24A PE=4 SV=1 CANONICAL=Q9VQU4-1" }, "isoforms": [ { "isoform_ac": "Q9VQU4-1", "url": "https://www.uniprot.org/uniprotkb/Q9VQU4/entry#Q9VQU4-1", "sequence": { "sequence": "MFRLSVLVLNLLLVSHEFSAGTAKIEIQPLPALCNGYCFPTLKPVMEYVAIHQDKWNTCTEILANEARKDQIQLNIQLDALKADVSNIKASQLSKDEKLDRMEREQFAMHESLETINRYLTVKLDRTKLQLEAIKNTMDYMKAQMDGYFSAINGVQCLQPGFEKIGDRYFYIEEDVELNWLDAQAKCRRMGGHLASIKTKQEFDAIVEKLDDSKSYFLGVNENTKTGDFVSAASGKSCLYHEWGPGEPHHNNDQERCVSILRKLMHVGNCTYEKRFICQYGI", "length": 282, "header": "tr|Q9VQU4-1|Q9VQU4_DROME Isoform 1 of Lectin-24A OS=Drosophila melanogaster OX=7227 GN=lectin-24A PE=4 SV=1 CANONICAL=Q9VQU4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VQU4", "url": "https://www.uniprot.org/uniprotkb/Q9VQU4" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VQU4", "url": "https://www.uniprot.org/uniprotkb/Q9VQU4" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQU4", "url": "https://www.uniprot.org/uniprotkb/Q9VQU4" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQU4", "url": "https://www.uniprot.org/uniprotkb/Q9VQU4" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VQU4", "url": "https://www.uniprot.org/uniprotkb/Q9VQU4" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VQU4", "url": "https://www.uniprot.org/uniprotkb/Q9VQU4" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VQU4", "url": "https://www.uniprot.org/uniprotkb/Q9VQU4" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQU4", "url": "https://www.uniprot.org/uniprotkb/Q9VQU4" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQU4", "url": "https://www.uniprot.org/uniprotkb/Q9VQU4" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VQU4", "url": "https://www.uniprot.org/uniprotkb/Q9VQU4" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VQU4", "url": "https://www.uniprot.org/uniprotkb/Q9VQU4" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG3410", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3410", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JU13-1", "protein_name": "C-type lectin domain family 4, member G", "gene_name": "Clec4g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNTGGYSKLGGVIEEAPRGQLGRWECYKERLFFLVLAFLVATVLWALILSILLSNASSQLRVLLNHQDLLRTNASKQKVMLSSLKDDVGACRNCCSVMKAQLQTTLAEFKDTQAKVMEQESNLKDLQERVTQDLAKASRDRENIRSELFRALETVKRQNSSCEQCPPSWLPFQGSCYYFSETQAIWDTAQSYCVGQGAHLVIVRDLNEQGFLSQHTRGRGYWLGLRADRRLNKIQGYRWVDGAPLTFSHWNSGEPNDSRGHEDCVMMLHSGLWNDAPCANERDGWICEKRSSC", "length": 293 }, "evidence": [ { "id": "RGD:1597482", "url": "https://alliancegenome.org/gene/RGD:1597482#orthology", "database": "AGR" }, { "id": "FB:FBgn0040104", "url": "https://alliancegenome.org/gene/FB:FBgn0040104#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A230-1", "protein_name": "CD209a molecule like 3", "gene_name": "Cd209al3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQCQVREGPNLEGLRRCMIMCIQAFIYPDPPLPIDSLCRPCPWEWTFFHGRCYYFSKSQRNWNDSVAACQEVDAQLVTVESDEEQTFLDTFLKNKGPAWMGLSDLKQESTWQWVDGSPLSDSFRKYWIKGEPNNQGNEDCAELREDGWNDNKCDNKKFWICKKPETSCSSK", "length": 171 }, "evidence": [ { "id": "HGNC:1641", "url": "https://alliancegenome.org/gene/HGNC:1641#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M1RLL2-1", "protein_name": "Uncharacterized protein dcsignlg", "gene_name": "dcsignlg", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEAVYENVECRDIKNSTGPQSQNHNRDEENDRKRRRWKCVVLVIMGLICALLLLFITLQNISITAERDLFKTYKNTVEELNHTISSLQHDNTDLETDKQQLEDKYNSLSLKKQQLETKYNSLSLGKQQLENRVTSLSAELKEARSKSGWFFMSTEAMSWSESRQFCRDRGADLVIIKSEEKQRFISSLVKEDTWIGLSVTETGGNKWKWVDNSPLNQGFWAKGEPNNYQGAKEDCVEVRISQGTPNNWNDRRCSDSRKAVCEK", "length": 263 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-090313-154", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-154#orthology", "database": "AGR" }, { "id": "FB:FBgn0040104", "url": "https://alliancegenome.org/gene/FB:FBgn0040104#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PGK7-1", "protein_name": "Immune-related, lectin-like receptor 3 isoform X1", "gene_name": "illr3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGSVYENSVFAFSTGNSDENDSQYKGHFSNYRESKREVNTAKWTKVLLIVFAVSLVFALGGLCAVRIQYVSVSAQLSAQETNGTIMSRQLDKLTANFTTVRDHLHINELLMKELTANYSRVKEQLSISEETVRKLSRFNQSSGCAICAIHWTHSGEKCYYFSTVKMNWTQSRDHCVTKGGHLVIITSQAEQEFLTSNVKETHWIGLNDLDTEGRWLWVDNQPLSQTEEFWMKRENGVSEPDNWTKQHVDGEDCASLGHPDGETDFWTDAYCFEEKRFVCEAAAAV", "length": 285 }, "evidence": [ { "id": "MGI:1861232", "url": "https://alliancegenome.org/gene/MGI:1861232#orthology", "database": "AGR" }, { "id": "MGI:1861231", "url": "https://alliancegenome.org/gene/MGI:1861231#orthology", "database": "AGR" }, { "id": "HGNC:13257", "url": "https://alliancegenome.org/gene/HGNC:13257#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9Q0P0-1", "protein_name": "Uncharacterized protein hbl1 isoform X1", "gene_name": "hbl1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTRIHAWRRGVYSKKTPFSSHVGNFSFVVFVRSLKERLSIEAQMALLKLFLGALLLLQLVLQLLAGAADPQTLNCPAYAGVPGTPGHNGLPGRDGRDGRDGVTGPKGEKGEPGVSVQGPPGKAGPPGPDGAQGESGPPGSPGSESVIESLKSEIQNLKAKIDTIEKAASFSNFRKVGQKYYVTDRIFGTFDNGIKLCESSSGTLVVPKSSAENQALVRVAASSGLINEKPYIGVTDKETEGQFVDIEGKQLTFTKWGPGQPDDYQGAQDCGVIDVSGTWDDGNCGDIRPIICEIDIK", "length": 297 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-285", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-285#orthology", "database": "AGR" }, { "id": "FB:FBgn0040104", "url": "https://alliancegenome.org/gene/FB:FBgn0040104#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TVV3-1", "protein_name": "Asialoglycoprotein receptor 2", "gene_name": "asgr1c.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRRGWSLFFNFKNQPLILVPLFLLSQNMEMHSSEEYMKMEVECETKQSLCKGRPCSKQTGILVLLGTVGMIIFLVLISIIVQAKKLSDIETLMTDLSSSLDSLTSKHEENQQKLERQQNVSYIQVKKQMDTVRASVSSIMSKLKADSVRTSFMFRHPLERFLIEHSSEELESGCSDSAWVPFGNSCYLFSRDKMNWTEAKDYCEEKGAWLLKIEDDSEDEWQFVTDFANPTHYWIGLTDQNTGQWRWADGTNYTMNKEHWGPGQPDEWTEHSLGEEGEDCAEITYESLLNDLHCSSKIKFICEMKT", "length": 306 }, "evidence": [ { "id": "HGNC:16916", "url": "https://alliancegenome.org/gene/HGNC:16916#orthology", "database": "AGR" }, { "id": "MGI:88082", "url": "https://alliancegenome.org/gene/MGI:88082#orthology", "database": "AGR" }, { "id": "MGI:88081", "url": "https://alliancegenome.org/gene/MGI:88081#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABK0LKH2-1", "protein_name": "CD209c molecule", "gene_name": "Cd209c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGDSEEDRVQQLSSLDEEHLIASSTRYSLQGFRFQPPYILKKAAGYLCHGLVPFVLQLICLTLCAILLLAILIKVSNVAYSQGQEQAKKEKVYQDVAQLKPQINHLCRPCPWDWTFFQGNCYFFSKFQQNWKDSVTSCRKLGAQLVVVKSDDEQSFLQQTSKEKGYAWMVLSDLKREGIWHWVDGSHLLFSFTKYWNKGEPNNEWEEDCAEFRGDGWNDAPCTNKKYWICKKSALSCTGK", "length": 240 }, "evidence": [ { "id": "HGNC:1641", "url": "https://alliancegenome.org/gene/HGNC:1641#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A9C461-1", "protein_name": "Asialoglycoprotein receptor-like 1", "gene_name": "asgrl1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKTAIRTLTAADEQKSPHKLTLYNMETVSYDRFTSAETEINHSGQKFIMQSDCFLFPSTGRRNRMIYIIYAILALYVFILTLAVGIKISQISQEVADVRLYMKTFVDAPKTPQFENGHFSELVMQVPVAEQGPCQENWVFYKGSCYFQSTMKRNWKTAESNCIQKGSHLVVVNDLAELDFLSSIVKLSDSYWIGLVEKEEGQWSWVDGTEFSATEHHWDVGQPDDWDVRVNGEDCGQLHSREIVNRRRMWNDADCTLSYPYICEGNPKSH", "length": 270 }, "evidence": [ { "id": "MGI:88082", "url": "https://alliancegenome.org/gene/MGI:88082#orthology", "database": "AGR" }, { "id": "MGI:88081", "url": "https://alliancegenome.org/gene/MGI:88081#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "B0S6P2-1", "protein_name": "Lectin isoform X1", "gene_name": "lectin", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMVMLRSLLLLSLFSMGNAAARRCTRQWSRFGSRCFRYFSVPVNWVTAERNCQLLGGNLVSVQNGMENDFLLSLIPNSERFFIGGYDGEDEENWFWSEGSSFGYTNWCSGEPNNMNTEHCLEINWTSDRCWNNLPCSTEQGYICAKNLDGCS", "length": 152 }, "evidence": [ { "id": "MGI:1861231", "url": "https://alliancegenome.org/gene/MGI:1861231#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "B7Z0K3-1", "protein_name": "C-type lectin domain-containing protein", "gene_name": "Dmel\\CG14866", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPPAGQQLRLTALVYLALGIALLCNGSDGETRQKYANESLADADDPSPVWSQFLEDYVLSQGSSSSGSQRKSKDLPYMGADMGINGPLSYHSSAYKRPGNNIYITRRIGEAVELEPHLRKPVESQSPIVNPQFRPMTNQMLHQQHQQMQQQQQQQQLQQRQQPGFLQQLFGIGGSGGGGGSGTQQQQHVRPVPLQQQQVQQIAQQHPQQQHLVGGQPTTFRAVSENDLYLLGAIEKLVYRVDYLESRVRRSEQLIYYLMAGNNQKEVKDPCPANFTRISDNCYYINSQQQVNWKTANSACKGLNSHLAEFEKVSENEEIMAYLLNQPTHRGRDYWLGGLNPGLLWIWSNSAKPVNPNMNLTSIAMAQKGENSTAANLVDSSEQAAEEATGEDVLNNTVQIEGKGRCLRLSYNAGKHSYVYYGQECTSRHYYICEHEDKTLDNKIKKITRELKLFE", "length": 455 }, "evidence": [ { "id": "MGI:1917442", "url": "https://alliancegenome.org/gene/MGI:1917442#orthology", "database": "AGR" }, { "id": "MGI:1916392", "url": "https://alliancegenome.org/gene/MGI:1916392#orthology", "database": "AGR" }, { "id": "MGI:1861232", "url": "https://alliancegenome.org/gene/MGI:1861232#orthology", "database": "AGR" }, { "id": "MGI:1861231", "url": "https://alliancegenome.org/gene/MGI:1861231#orthology", "database": "AGR" }, { "id": "MGI:2157947", "url": "https://alliancegenome.org/gene/MGI:2157947#orthology", "database": "AGR" }, { "id": "HGNC:16916", "url": "https://alliancegenome.org/gene/HGNC:16916#orthology", "database": "AGR" }, { "id": "HGNC:1641", "url": "https://alliancegenome.org/gene/HGNC:1641#orthology", "database": "AGR" }, { "id": "HGNC:13257", "url": "https://alliancegenome.org/gene/HGNC:13257#orthology", "database": "AGR" }, { "id": "MGI:88082", "url": "https://alliancegenome.org/gene/MGI:88082#orthology", "database": "AGR" }, { "id": "MGI:88081", "url": "https://alliancegenome.org/gene/MGI:88081#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "D3Z5D4-1", "protein_name": "CD209g antigen", "gene_name": "Cd209g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLATLVQVSRIRAYSQGQTQDQQGSSSLDKVAVPREQTHSGLEQIQQIQQQLTQFNASLAGLCRPCPWDWELFQGSCYLFSRTLGSWETSASSCEDLGAHLVIVNSVSEQQFLKYWHIRKNQLTWIGLSDHRSEGSWQWVDDTPLKLSFWKEGEPNNEGDEDCVVMAEDKWNDSRCTANNFWVCEQPSAPCPGY", "length": 194 }, "evidence": [ { "id": "MGI:1917442", "url": "https://alliancegenome.org/gene/MGI:1917442#orthology", "database": "AGR" }, { "id": "FB:FBgn0040104", "url": "https://alliancegenome.org/gene/FB:FBgn0040104#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZCF3-1", "protein_name": "CD209e molecule", "gene_name": "Cd209e", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRIQQMGSLGFLDRSNIPLVLQLLFLILFAGLLVAIVIQVSKIPSSEEVQWEQTKQEKMYQDLSQLKSEIDSLCRLCPWDWTFFNGNCYFFSKSQRDWHNSITACQEMEAQLVTIKSPEEQSFLQQTSKKNGYTWMGLSDLNKEGEWYWLDGSPLSDSLRNYWNEGQPNNIDGQDCVEFRNDGWNDAKCDNWKFWICKKTATTCSSK", "length": 207 }, "evidence": [ { "id": "HGNC:1641", "url": "https://alliancegenome.org/gene/HGNC:1641#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZP17-1", "protein_name": "CD209a molecule", "gene_name": "Cd209a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSESKETGKQQLGPLDEELLTSSHTRYSMKGFGFQPNSGFSSFTGYLVHSHVPLALKALFLTVFSVLLVVILVKVYKIPSSHEQEESNQKNFYQELIQLKAGVDRLCRSCPWDWTAFQGNCYFFSVAQKSWNDSATACHNVGAQLVVIKSEEEQNFLQKTSKKRGYTWMGLIDINKESTWHWVDGSPLTLTFMKYWNKGEPNNVGDKDCAEFREDGWNDTKCDNKKFWICKKPETSCSSK", "length": 240 }, "evidence": [ { "id": "HGNC:1641", "url": "https://alliancegenome.org/gene/HGNC:1641#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZXM6-1", "protein_name": "C-type lectin domain family 6, member A, pseudogene 1", "gene_name": "Clec6a-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVQERHPQRKGVCWTLRLWSTAVISMLLLSTCFIASCMVTYQFTMEKPNRRLSELHTYHSSLTCCSKGTMVSEKLWGCCPNHWKSFGSSCYLISTKENFWSISEQNYIHMGAHLVVINTETEQNFITQQLNESLSYFLGLSDPQGNSKWQWIDNTPFSQNVRFWHPHEPNLPEEWCASIVYWNPSKWGWNDVFCDSKHNSICETKKIYL", "length": 209 }, "evidence": [ { "id": "MGI:1861231", "url": "https://alliancegenome.org/gene/MGI:1861231#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZXN3-1", "protein_name": "CD209d molecule", "gene_name": "Cd209d", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCFKSGLRAHLIVPILEWETPAFWTSAEYNTLCFYILFECRVSFLGESWTLRKHECLESGYKGTTKTGLSQTRALAIAVTMSESMESNTQQLDNPEDEEYLMSGSRYSIISSRLRTKFGIKSLAEYTKQSHNPLVLPLLSFLFLAGLLLIILVLVSKVPSSEVQDKIYQELMQLKTEVHDGLCQPCPRDWTFFNGSCYFFSKSQRNWHNSITACKELGAQLVIVETDEEQTFLQQTSKTRGPTWMGLSDMHNEATWHWVDGSPLSPSFAQYWNRGEPNNVGDEDCAEFSGDGWNDLRCDTRIFWICKKVSTSSCTIK", "length": 317 }, "evidence": [ { "id": "MGI:2157947", "url": "https://alliancegenome.org/gene/MGI:2157947#orthology", "database": "AGR" }, { "id": "HGNC:1641", "url": "https://alliancegenome.org/gene/HGNC:1641#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9PT25-1", "protein_name": "C-type lectin domain family 4, member A3", "gene_name": "Clec4a3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSENIYINTNFKNKYDSSDIDTDFRPDPPKKSKSQKSCHKFSKVLFTSLIIYFLLLTILFSSALIILFKKYSQLLEEKTIMKELNYTELECTKWDSLSEDKVWSCCPKDWKPFDSNCYFPSTDSVESWMESEEKCSGIGAHLVVIHSQEEQDFLPRILDTHAAYFIGLSDPGHRQWQWVDQTPYNGNATFWHEGEPSSDNEQCVIINHHENTGWGWSDSSCSDKQKLVCQVKKIYL", "length": 237 }, "evidence": [ { "id": "HGNC:13257", "url": "https://alliancegenome.org/gene/HGNC:13257#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LYU9-1", "protein_name": "CD209f molecule like 1", "gene_name": "Cd209fl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLYKSQVRGKEETGSPEKQKMAGKPELHQLNNHEEEVTLEDQGFAENDPEGLICSSKSLQGHLTRAPWLLLLLISLGLFLLMLAILVQVSRICANPQGQTQDQKGSSSLGKVAVPQEQTHTGLEQIQQIQQIQQQLTQFNASLAGLCRPCPWDWEFFQGSCYLFSRTLASWGASASSCKDLGAHLVIINSVAEQRFMKYWNVRKNQRSWIGLSDHLREGSWQWVDHSPLKFSFWKEGEPNNDGDEDCVELFMDEWNDNTCTQQNFWVCEQPSAPCPGHGRSVLS", "length": 285 }, "evidence": [ { "id": "MGI:1916392", "url": "https://alliancegenome.org/gene/MGI:1916392#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M698-1", "protein_name": "CD209f molecule", "gene_name": "Cd209f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGKPELHQPNNHEEEVTLEDHDPEGLICSSKSLQGHLTRAPWLLPLLISLGLFLLMLATLVQISRICANPQGQTQDQKGSSSFGKVAVPQEQTYTGLEQIQQIQQQLTQFNASLAGLCRPCPWDWEFFQGSCYLFSRTLASWGASASSCKDLGAHLVIVNSVAEQQFLKYWHIRQSQLTWIGLSDHQREGSWQWVDDTPLKLSFWKEGEPNNAGDEDCVVIAEDKWNDSTCSANNFWVCEQPSTPCPGHARSALP", "length": 256 }, "evidence": [ { "id": "MGI:1917442", "url": "https://alliancegenome.org/gene/MGI:1917442#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QW96-1", "protein_name": "CD209 antigen", "gene_name": "cd209", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNTLSYREEDRGKKAVIKAAMSRAEAHKDSDGLLKDKMSDIYEAVESTGPDGERVEMMVNIYESADYVIDHDLQTNPQQPLQQTGSICLKKRRSRASPVCVVLLCSLLMTAVTVLSLYVYTNYTQETRITSLTEERDQLLTNITNLTEEKAKLLASNTNLKVEKDQQLKMMKAMKDQLENIIKNLLKENKQFSSKNEDLLKQSAQLKKEKKDLEKRLHEQDSWFYFQSSFYFISSEERNWTESRRYCRDKGADLIIINNREEQDHVKKMSGGFTVWIGLTDSDDRWKWIDGTNMTTGFRFWNHGEPNGQGGENCVTSRSSGWADYPCFYPFPWICEKNTLKCQ", "length": 343 }, "evidence": [ { "id": "HGNC:1641", "url": "https://alliancegenome.org/gene/HGNC:1641#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F8W3Q0-1", "protein_name": "Asialoglycoprotein receptor 1", "gene_name": "asgr1a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRVVSSDSGSVTVANTEYTDETESAETSDHTEFWRGDPSVRRLAAVPSGGRWRWCAGIAGSVAALMLLLLIITVSVNHVKFNRKFSATEVRIQNLTQIILNVISRTQELEQFGHKINADVSSLEFDQRMTETSMNNLLESAQALHDKVSELKCHIDKMRNNNTQELCCPDQWSLFSSNCYFFSTDGMSWDSARDECERKRAKLLILTSKLEKSFVVSKTKPLFYWLGLTDGRTGEWEWLDETPYEMVRSEWRPGQPDNWKAHGLGGGEDCAHFHHDGRYNDDHCSRHYRYICKAAASAI", "length": 299 }, "evidence": [ { "id": "HGNC:16916", "url": "https://alliancegenome.org/gene/HGNC:16916#orthology", "database": "AGR" }, { "id": "MGI:88082", "url": "https://alliancegenome.org/gene/MGI:88082#orthology", "database": "AGR" }, { "id": "MGI:88081", "url": "https://alliancegenome.org/gene/MGI:88081#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3UVT9-1", "protein_name": "CD209f antigen", "gene_name": "Cd209f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGEPEFHQSKNHEEEVTSGEQGFAEHDPEGLICSSKSLQGHLTQVPWLLLLLISLGLFLLMLATLVQVSRIRAYSQGQTQDQQGSSSLDKVAVPREQTHSGLEQIQQIQQQLTQFNASLAGLCRPCPWDWELFQGSCYLFSRTLGSWETSASSCEDLGAHLVIVNSVSEQRFMKYWNVRKNQRSWIGLSDHIHEGSWQWVDGSALKFSFWKEGEPNNDGDEDCVELFMDDWNDNKCTEQNFWVCEQPSAPCPHH", "length": 255 }, "evidence": [ { "id": "MGI:1916392", "url": "https://alliancegenome.org/gene/MGI:1916392#orthology", "database": "AGR" }, { "id": "FB:FBgn0040104", "url": "https://alliancegenome.org/gene/FB:FBgn0040104#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P02706-1", "protein_name": "Asialoglycoprotein receptor 1", "gene_name": "Asgr1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKDYQDFQHLDNENDHHQLQRGPPPAPRLLQRLCSGFRLFLLSLGLSILLLVVVCVITSQNSQLREDLRVLRQNFSNFTVSTEDQVKALTTQGERVGRKMKLVESQLEKHQEDLREDHSRLLLHVKQLVSDVRSLSCQMAALRGNGSERICCPINWVEYEGSCYWFSSSVKPWTEADKYCQLENAHLVVVTSWEEQRFVQQHMGPLNTWIGLTDQNGPWKWVDGTDYETGFKNWRPGQPDDWYGHGLGGGEDCAHFTTDGHWNDDVCRRPYRWVCETELGKAN", "length": 284 }, "evidence": [ { "id": "MGI:88081", "url": "https://alliancegenome.org/gene/MGI:88081#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P07306-1", "protein_name": "Asialoglycoprotein receptor 1", "gene_name": "ASGR1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTKEYQDLQHLDNEESDHHQLRKGPPPPQPLLQRLCSGPRLLLLSLGLSLLLLVVVCVIGSQNSQLQEELRGLRETFSNFTASTEAQVKGLSTQGGNVGRKMKSLESQLEKQQKDLSEDHSSLLLHVKQFVSDLRSLSCQMAALQGNGSERTCCPVNWVEHERSCYWFSRSGKAWADADNYCRLEDAHLVVVTSWEEQKFVQHHIGPVNTWMGLHDQNGPWKWVDGTDYETGFKNWRPEQPDDWYGHGLGGGEDCAHFTDDGRWNDDVCQRPYRWVCETELDKASQEPPLL", "length": 291 }, "evidence": [ { "id": "MGI:88081", "url": "https://alliancegenome.org/gene/MGI:88081#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P07307-1", "protein_name": "Asialoglycoprotein receptor 2", "gene_name": "ASGR2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKDFQDIQQLSSEENDHPFHQGEGPGTRRLNPRRGNPFLKGPPPAQPLAQRLCSMVCFSLLALSFNILLLVVICVTGSQSEGHGGAQLQAELRSLKEAFSNFSSSTLTEVQAISTHGGSVGDKITSLGAKLEKQQQDLKADHDALLFHLKHFPVDLRFVACQMELLHSNGSQRTCCPVNWVEHQGSCYWFSHSGKAWAEAEKYCQLENAHLVVINSWEEQKFIVQHTNPFNTWIGLTDSDGSWKWVDGTDYRHNYKNWAVTQPDNWHGHELGGSEDCVEVQPDGRWNDDFCLQVYRWVCEKRRNATGEVA", "length": 311 }, "evidence": [ { "id": "MGI:88082", "url": "https://alliancegenome.org/gene/MGI:88082#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P08290-1", "protein_name": "Asialoglycoprotein receptor 2", "gene_name": "Asgr2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEKDFQDIQQLDSEENDHQLIGDEEQGSHVQNLRTENPRWGGQPPSRPFPQRLCSKFRLSLLALAFNILLLVVICVVSSQSMQLQKEFWTLKETLSNFSTTTLMEFKALDSHGGSRNDNLTSWETILEKKQKDIKADHSTLLFHLKHFPLDLRTLTCQLAFFLSNGTECCPVNWVEFGGSCYWFSRDGLTWAEADQYCQMENAHLLVINSREEQEFVVKHRGAFHIWIGLTDKDGSWKWVDGTEYRSNFKNWAFTQPDNWQGHEEGGSEDCAEILSDGLWNDNFCQQVNRWACERKRDITY", "length": 301 }, "evidence": [ { "id": "MGI:88082", "url": "https://alliancegenome.org/gene/MGI:88082#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P10716-1", "protein_name": "C-type lectin domain family 4 member F", "gene_name": "Clec4f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKEAELNRDVAKFCTDNQCVILQPQGLGPKSAAPMAPRTLRHVQAIVALVVVTVFFSLLALFVVVLQPWRQKQNEDHPVKAGLHGGNYSGSDNCSQFVRRAEMQEAIQSLRASGNSSSCHKEIQTLKYQMDNVSSQVQLLGGHLEEANADIQQAKDVLKGTGALASETQALRSSLEVASADIHSLRGDLEKANAMTSQTQGLLKSSTDNTSAELHVLGRGLEEAQSEIQALRGSLQSSNDLGSRTQNFLQHSMDNISAEIQAMRDGMQRAGEEMTSLKKDLETLTAQIQNANGHLEQTDTQIQGLKAQLKSTSSLNSQIEVVNGKLKDSSRELQTLRRDLSDVSALKSNVQMLQSNLQKAKAEVQSLKTGLEATKTLAAKIQGQQSDLEALQKAVAAHTQGQKTQNQVLQLIMQDWKYFNGKFYYFSRDKKSWHEAENFCVSQGAHLASVTSQEEQAFLVQITNAVDHWIGLTDQGTEGNWRWVDGTPFDYVQSRRFWRKGQPDNWRHGNGEREDCVHLQRMWNDMACGTAYNWVCKKSTDWSVARTDQS", "length": 550 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-090313-154", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-154#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P11226-1", "protein_name": "Mannose-binding protein C", "gene_name": "MBL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLFPSLPLLLLSMVAASYSETVTCEDAQKTCPAVIACSSPGINGFPGKDGRDGTKGEKGEPGQGLRGLQGPPGKLGPPGNPGPSGSPGPKGQKGDPGKSPDGDSSLAASERKALQTEMARIKKWLTFSLGKQVGNKFFLTNGEIMTFEKVKALCVKFQASVATPRNAAENGAIQNLIKEEAFLGITDEKTEGQFVDLTGNRLTYTNWNEGEPNNAGSDEDCVLLLKNGQWNDVPCSTSHLAVCEFPI", "length": 248 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-285", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-285#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P19999-1", "protein_name": "Mannose-binding protein A", "gene_name": "Mbl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLLLPLLVLLCVVSVSSSGSQTCEETLKTCSVIACGRDGRDGPKGEKGEPGQGLRGLQGPPGKLGPPGSVGAPGSQGPKGQKGDRGDSRAIEVKLANMEAEINTLKSKLELTNKLHAFSMGKKSGKKFFVTNHERMPFSKVKALCSELRGTVAIPRNAEENKAIQEVAKTSAFLGITDEVTEGQFMYVTGGRLTYSNWKKDEPNDHGSGEDCVTIVDNGLWNDISCQASHTAVCEFPA", "length": 238 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-285", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-285#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24721-1", "protein_name": "Asialoglycoprotein receptor 2", "gene_name": "Asgr2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKDCQDIQQLDSEENDHQLSGDDEHGSHVQDPRIENPHWKGQPLSRPFPQRLCSTFRLSLLALAFNILLLVVICVVSSQSIQLQEEFRTLKETFSNFSSSTLMEFGALDTLGGSTNAILTSWLAQLEEKQQQLKADHSTLLFHLKHFPMDLRTLTCQLAYFQSNGTECCPVNWVEFGGSCYWFSRDGLTWAEADQYCQLENAHLLVINSREEQDFVVKHRSQFHIWIGLTDRDGSWKWVDGTDYRSNYRNWAFTQPDNWQGHEQGGGEDCAEILSDGHWNDNFCQQVNRWVCEKRRNITH", "length": 301 }, "evidence": [ { "id": "MGI:88082", "url": "https://alliancegenome.org/gene/MGI:88082#orthology", "database": "AGR" }, { "id": "FB:FBgn0040104", "url": "https://alliancegenome.org/gene/FB:FBgn0040104#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P34927-1", "protein_name": "Asialoglycoprotein receptor 1", "gene_name": "Asgr1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTKDYQDFQHLDNDNDHHQLRRGPPPTPRLLQRLCSGSRLLLLSSSLSILLLVVVCVITSQNSQLREDLLALRQNFSNLTVSTEDQVKALSTQGSSVGRKMKLVESKLEKQQKDLTEDHSSLLLHVKQLVSDVRSLSCQMAAFRGNGSERTCCPINWVEYEGSCYWFSSSVRPWTEADKYCQLENAHLVVVTSRDEQNFLQRHMGPLNTWIGLTDQNGPWKWVDGTDYETGFQNWRPEQPDNWYGHGLGGGEDCAHFTTDGRWNDDVCRRPYRWVCETKLDKAN", "length": 284 }, "evidence": [ { "id": "MGI:88081", "url": "https://alliancegenome.org/gene/MGI:88081#orthology", "database": "AGR" }, { "id": "FB:FBgn0040104", "url": "https://alliancegenome.org/gene/FB:FBgn0040104#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P35247-1", "protein_name": "Pulmonary surfactant-associated protein D", "gene_name": "SFTPD", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLLFLLSALVLLTQPLGYLEAEMKTYSHRTMPSACTLVMCSSVESGLPGRDGRDGREGPRGEKGDPGLPGAAGQAGMPGQAGPVGPKGDNGSVGEPGPKGDTGPSGPPGPPGVPGPAGREGPLGKQGNIGPQGKPGPKGEAGPKGEVGAPGMQGSAGARGLAGPKGERGVPGERGVPGNTGAAGSAGAMGPQGSPGARGPPGLKGDKGIPGDKGAKGESGLPDVASLRQQVEALQGQVQHLQAAFSQYKKVELFPNGQSVGEKIFKTAGFVKPFTEAQLLCTQAGGQLASPRSAAENAALQQLVVAKNEAAFLSMTDSKTEGKFTYPTGESLVYSNWAPGEPNDDGGSEDCVEIFTNGKWNDRACGEKRLVVCEF", "length": 375 }, "evidence": [ { "id": "HGNC:10803", "url": "https://alliancegenome.org/gene/HGNC:10803#orthology", "database": "AGR" }, { "id": "MGI:109515", "url": "https://alliancegenome.org/gene/MGI:109515#orthology", "database": "AGR" }, { "id": "FB:FBgn0040104", "url": "https://alliancegenome.org/gene/FB:FBgn0040104#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P35248-1", "protein_name": "Pulmonary surfactant-associated protein D", "gene_name": "Sftpd", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLHFLSMLVLLVQPLGDLGAEMKTLSQRSITNTCTLVLCSPTENGLPGRDGRDGREGPRGEKGDPGLPGPMGLSGLPGPRGPVGPKGENGSAGEPGPKGERGLVGPPGSPGISGPAGKEGPSGKQGNIGPQGKPGPKGEAGPKGEVGAPGMQGSAGAKGPAGPKGERGAPGEQGAPGNAGAAGPAGPAGPQGAPGSRGPPGLKGDRGAPGDRGIKGESGLPDSAALRQQMEALNGKLQRLEAAFSRYKKAALFPDGQSVGDKIFRAANSEEPFEDAKEMCRQAGGQLASPRSATENAAVQQLVTAHSKAAFLSMTDVGTEGKFTYPTGEALVYSNWAPGEPNNNGGAENCVEIFTNGQWNDKACGEQRLVICEF", "length": 374 }, "evidence": [ { "id": "HGNC:10803", "url": "https://alliancegenome.org/gene/HGNC:10803#orthology", "database": "AGR" }, { "id": "MGI:109515", "url": "https://alliancegenome.org/gene/MGI:109515#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P41317-1", "protein_name": "Mannose-binding protein C", "gene_name": "Mbl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSIFTSFLLLCVVTVVYAETLTEGVQNSCPVVTCSSPGLNGFPGKDGRDGAKGEKGEPGQGLRGLQGPPGKVGPTGPPGNPGLKGAVGPKGDRGDRAEFDTSEIDSEIAALRSELRALRNWVLFSLSEKVGKKYFVSSVKKMSLDRVKALCSEFQGSVATPRNAEENSAIQKVAKDIAYLGITDVRVEGSFEDLTGNRVRYTNWNDGEPNNTGDGEDCVVILGNGKWNDVPCSDSFLAICEFSD", "length": 244 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-285", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-285#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P49300-1", "protein_name": "C-type lectin domain family 10 member A", "gene_name": "Clec10a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIYENLQNSRIEEKTQEPGKAPSQSFLWRILSWTHLLLFSLGLSLLLLVVVSVIGSQNSQLRRDLGTLRATLDNTTSKIKAEFQSLDSRADSFEKGISSLKVDVEDHRQELQAGRDLSQKVTSLESTVEKREQALKTDLSDLTDHVQQLRKDLKALTCQLANLKNNGSEVACCPLHWTEHEGSCYWFSESEKSWPEADKYCRLENSHLVVVNSLEEQNFLQNRLANVVSWIGLTDQNGPWRWVDGTDFEKGFKNWAPLQPDNWFGHGLGGGEDCAHITTGGPWNDDVCQRTFRWICEMKLAKES", "length": 304 }, "evidence": [ { "id": "HGNC:16916", "url": "https://alliancegenome.org/gene/HGNC:16916#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P49301-1", "protein_name": "C-type lectin domain family 10 member A", "gene_name": "Clec10a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTMAYENFQNLGSEEKNQEAGKAPPQSFLCNILSWTHLLLFSLGLSLLLLVVISVIGSQNSQLRRDLETLRTTLDNTTSNTKAELQALASRGDSLQTGINSLKVEVDDHGQELQAGRGLSQKVASLESTVEKKEQTLRTDLSEITDRVQQLGKDLKTLTCQLASLKNNGSAVACCPLHWMEHEGSCYWFSQSGKPWPEADKYCQLENSNLVVVNSLAEQNFLQTHMGSVVTWIGLTDQNGPWRWVDGTDYEKGFTHWAPKQPDNWYGHGLGGGEDCAHFTSDGRWNDDVCQRPYRWVCEMKLAKDS", "length": 306 }, "evidence": [ { "id": "HGNC:16916", "url": "https://alliancegenome.org/gene/HGNC:16916#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P50404-1", "protein_name": "Pulmonary surfactant-associated protein D", "gene_name": "Sftpd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPFLSMLVLLVQPLGNLGAEMKSLSQRSVPNTCTLVMCSPTENGLPGRDGRDGREGPRGEKGDPGLPGPMGLSGLQGPTGPVGPKGENGSAGEPGPKGERGLSGPPGLPGIPGPAGKEGPSGKQGNIGPQGKPGPKGEAGPKGEVGAPGMQGSTGAKGSTGPKGERGAPGVQGAPGNAGAAGPAGPAGPQGAPGSRGPPGLKGDRGVPGDRGIKGESGLPDSAALRQQMEALKGKLQRLEVAFSHYQKAALFPDGRSVGDKIFRTADSEKPFEDAQEMCKQAGGQLASPRSATENAAIQQLITAHNKAAFLSMTDVGTEGKFTYPTGEPLVYSNWAPGEPNNNGGAENCVEIFTNGQWNDKACGEQRLVICEF", "length": 374 }, "evidence": [ { "id": "HGNC:10803", "url": "https://alliancegenome.org/gene/HGNC:10803#orthology", "database": "AGR" }, { "id": "MGI:109515", "url": "https://alliancegenome.org/gene/MGI:109515#orthology", "database": "AGR" }, { "id": "FB:FBgn0040104", "url": "https://alliancegenome.org/gene/FB:FBgn0040104#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P70194-1", "protein_name": "C-type lectin domain family 4 member F", "gene_name": "Clec4f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKEAELNRDMARYCTDNQCVSLQPQGLGPKSAALMAPRTLRHVQVILALMVVTVIFSLLALFVVASQPWRPEWNKEPPSLLLRGSNNSGHDNHSQFVRETEMQVAIQRLRDYEENSSSCHKEVQILKYQMDNVSSLVQLLGSHLEDVNADILQTKDVLKESGALALETQALRSSLEVASADIHSLRGDLEKANAMTSQTRGLLKSSTENTSAELHVLGRGLEEAQSEIQALRGSLQSANDLSSQTQGFLQHSMDNISAQIQTVRDGMERAGEKMNSLKKELETLTAQTQKANGHLEQTDAQIQGLKAELKSTSSLNSRIEVVNGQMKDASRELQTLRRDLSDVSALKSNVQMLQSNLQRAKTEMQTLKADLQATKALTAKIQGEQNRLGALQEAVAAQKQEQKTQNQVLQLIAQNWKYFNGNFYYFSRDKKPWREAEKFCTSQGAHLASVTSQEEQAFLVQTTSSGDHWIGLTDQGTEGIWRWVDGTPFNNAQSKGFWGKNQPDNWRHRNGEREDCVHVRQQWNDMACGSSYPWVCKKSTGWSAARVG", "length": 548 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-090313-154", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-154#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q59DY5-1", "protein_name": "C-type lectin 37Db", "gene_name": "lectin-37Db", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MMVKLLLLFLVCWSALPLESSPLGNRYNLEIGEKQYYISLAKTNWFEASNHCRQNGGFLLNLESREELELLSPHLHPAYSYWLSINDLGERGVYVSEATGLEAPFLNWSAGEPDNSSGYDRCVELWLSTTSFQMNDLPCYSSVAFICQLN", "length": 150 }, "evidence": [ { "id": "MGI:1861232", "url": "https://alliancegenome.org/gene/MGI:1861232#orthology", "database": "AGR" }, { "id": "MGI:1861231", "url": "https://alliancegenome.org/gene/MGI:1861231#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q67EQ0-1", "protein_name": "C-type lectin domain family 4 member A", "gene_name": "Clec4a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASEITYAEVRIKNESNSSVTYSGSPAAPREKPTRHLSKPGSLLVPFTSLMVLLLLLAITFLVAFIIYFQKYSQFLEEKKAIKGITHKELNCIKNVLLMEEKSWSCCPKNWKPFGSHCYWVTKHTSTYSKASWSESEKNCFSMGAHLLVIHSKEEQDFITGILNRDAAYFIGLWDSGHRQWQWVSQTPYNASATFWHKGEPSSDDEKCVIINHLNSGWGWNDIPCSGKQQSVCQMKKIQL", "length": 240 }, "evidence": [ { "id": "HGNC:13257", "url": "https://alliancegenome.org/gene/HGNC:13257#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q67EQ1-1", "protein_name": "C-type lectin domain family 4 member E", "gene_name": "Clec4e", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNSTKSPASHHTERECFKNSQVLSWTMAGASILFLSVCFITRCVVTYHSFQIYGQKKLQPHKTIKELSCYLEASGSVKNCCPLNWKHFQSSCYFFSTTTLSWLSSLKNCSDMGAHLVVINTWEEQEFLFRTKPRKKEFYIGLTDQVVEGQWRWVDDTPFTESLSFWDAGEPNNIVFVEDCATMRDSSNPRKNWNDVSCFFSMPWICEMPEISPLD", "length": 215 }, "evidence": [ { "id": "MGI:1861232", "url": "https://alliancegenome.org/gene/MGI:1861232#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6EIG7-1", "protein_name": "C-type lectin domain family 6 member A", "gene_name": "CLEC6A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMQEQQPQSTEKRGWLSLRLWSVAGISIALLSACFIVSCVVTYHFTYGETGKRLSELHSYHSSLTCFSEGTKVPAWGCCPASWKSFGSSCYFISSEEKVWSKSEQNCVEMGAHLVVFNTEAEQNFIVQQLNESFSYFLGLSDPQGNNNWQWIDKTPYEKNVRFWHLGEPNHSAEQCASIVFWKPTGWGWNDVICETRRNSICEMNKIYL", "length": 209 }, "evidence": [ { "id": "MGI:1861231", "url": "https://alliancegenome.org/gene/MGI:1861231#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6UXB4-1", "protein_name": "C-type lectin domain family 4 member G", "gene_name": "CLEC4G", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDTTRYSKWGGSSEEVPGGPWGRWVHWSRRPLFLALAVLVTTVLWAVILSILLSKASTERAALLDGHDLLRTNASKQTAALGALKEEVGDCHSCCSGTQAQLQTTRAELGEAQAKLMEQESALRELRERVTQGLAEAGRGREDVRTELFRALEAVRLQNNSCEPCPTSWLSFEGSCYFFSVPKTTWAAAQDHCADASAHLVIVGGLDEQGFLTRNTRGRGYWLGLRAVRHLGKVQGYQWVDGVSLSFSHWNQGEPNDAWGRENCVMMLHTGLWNDAPCDSEKDGWICEKRHNC", "length": 293 }, "evidence": [ { "id": "RGD:1597482", "url": "https://alliancegenome.org/gene/RGD:1597482#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BNX1-1", "protein_name": "C-type lectin domain family 4 member G", "gene_name": "Clec4g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNTGEYNKLGSAIEEVSRGQLGRWECYKQRLFFLVLALLVATVLWALILSTLLSSASSKLRVLLSHQDLLRTNASEQKMTLSSLKDDIGACRNCCSVTKAQLQTTLAEFKDIQAKLMEQESILKELQERVTQDLAKASRDRENIRSELFQALEAVKRQNSSCEQCPPSWLPFQGSCYYFSETQATWDTAQSYCGGQGAHLVIVRGLNEQGFLSQHTRGRGYWLGLRAVRHLNKIQGYRWVDGASLNFSHWNSGEPNDSRGHEDCIMMLHSGLWNDAPCTNERDGWICEKRSSCY", "length": 294 }, "evidence": [ { "id": "RGD:1597482", "url": "https://alliancegenome.org/gene/RGD:1597482#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CJ91-1", "protein_name": "CD209 antigen-like protein B", "gene_name": "Cd209b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDSTEAKMQPLSSMDDDELMVSGSRYSIKSSRLRPNSGIKCLAGCSGHSQVPLVLQLLSFLFLAGLLLIILFQVSKTPNTERQKEQEKILQELTQLTDELTSRIPISQGKNESMQAKITEQLMQLKTELLSRIPIFQGQNESIQEKISEQLMQLKAELLSKISSFPVKDDSKQEKIYQQLVQMKTELFRLCRLCPWDWTFLLGNCYFFSKSQRNWNDAVTACKEVKAQLVIINSDEEQTFLQQTSKAKGPTWMGLSDLKKEATWLWVDGSTLSSRFQKYWNRGEPNNIGEEDCVEFAGDGWNDSKCELKKFWICKKSATPCTEG", "length": 325 }, "evidence": [ { "id": "HGNC:1641", "url": "https://alliancegenome.org/gene/HGNC:1641#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IRH8-1", "protein_name": "Triforce, isoform B", "gene_name": "tfc", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MIRPTLIVVLISLASVDSGHNSPVTTIPVAEPISQVPHGFQLGQNNHISSSSNISRSGGGNGRDKRGAQLDPSEIARQNQITQQIFANYLERRLFPNRTANQKIPTIADILPKPKPSPRPRPRGFAASDGGNFKRSGGGAQRNRLAAAASKRQSGYNRKRLREEQEEEEEADDQERDQQPLANQEDFDYDVQESLQSVESEQHDQYYGNIFHRDPSENEVDNDCPNCVDESQYTPNKWTMPLLKLGEKRYYLGIFFKANWFKATQYCRYHGMHLASISSQEENDRLEKHIRDFGLGHEHFWISGTDLADEGNFFWMATGRPITFTNWNAGEPNNFRYENGEEENCLELWNRDGKGLKWNDSPCSFETYFVCEVQPN", "length": 376 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-090313-154", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-154#orthology", "database": "AGR" }, { "id": "HGNC:16916", "url": "https://alliancegenome.org/gene/HGNC:16916#orthology", "database": "AGR" }, { "id": "HGNC:1641", "url": "https://alliancegenome.org/gene/HGNC:1641#orthology", "database": "AGR" }, { "id": "HGNC:13257", "url": "https://alliancegenome.org/gene/HGNC:13257#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8IUN9-1", "protein_name": "C-type lectin domain family 10 member A", "gene_name": "CLEC10A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTRTYENFQYLENKVKVQGFKNGPLPLQSLLQRLCSGPCHLLLSLGLGLLLLVIICVVGFQNSKFQRDLVTLRTDFSNFTSNTVAEIQALTSQGSSLEETIASLKAEVEGFKQERQAGVSELQEHTTQKAHLGHCPHCPSVCVPVHSEMLLRVQQLVQDLKKLTCQVATLNNNASTEGTCCPVNWVEHQDSCYWFSHSGMSWAEAEKYCQLKNAHLVVINSREEQNFVQKYLGSAYTWMGLSDPEGAWKWVDGTDYATGFQNWKPGQPDDWQGHGLGGGEDCAHFHPDGRWNDDVCQRPYHWVCEAGLGQTSQESH", "length": 316 }, "evidence": [ { "id": "HGNC:16916", "url": "https://alliancegenome.org/gene/HGNC:16916#orthology", "database": "AGR" }, { "id": "FB:FBgn0040104", "url": "https://alliancegenome.org/gene/FB:FBgn0040104#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8N1N0-1", "protein_name": "C-type lectin domain family 4 member F", "gene_name": "CLEC4F", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDGEAVRFCTDNQCVSLHPQEVDSVAMAPAAPKIPRLVQATPAFMAVTLVFSLVTLFVVVQQQTRPVPKPVQAVILGDNITGHLPFEPNNHHHFGREAEMRELIQTFKGHMENSSAWVVEIQMLKCRVDNVNSQLQVLGDHLGNTNADIQMVKGVLKDATTLSLQTQMLRSSLEGTNAEIQRLKEDLEKADALTFQTLNFLKSSLENTSIELHVLSRGLENANSEIQMLNASLETANTQAQLANSSLKNANAEIYVLRGHLDSVNDLRTQNQVLRNSLEGANAEIQGLKENLQNTNALNSQTQAFIKSSFDNTSAEIQFLRGHLERAGDEIHVLKRDLKMVTAQTQKANGRLDQTDTQIQVFKSEMENVNTLNAQIQVLNGHMKNASREIQTLKQGMKNASALTSQTQMLDSNLQKASAEIQRLRGDLENTKALTMEIQQEQSRLKTLHVVITSQEQLQRTQSQLLQMVLQGWKFNGGSLYYFSSVKKSWHEAEQFCVSQGAHLASVASKEEQAFLVEFTSKVYYWIGLTDRGTEGSWRWTDGTPFNAAQNKAPGSKGSCPLRKYIIVNSGMGACSFIDTPPCPWILSN", "length": 589 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-090313-154", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-154#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q91ZW7-1", "protein_name": "CD209 antigen-like protein E", "gene_name": "Cd209e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRAPQMGSLGFLDKGHIPLVLQLLFLILFTGLLVAIIIQVSKMPSSEEIQWEHTKQEKMYKDLSQLKSEVDRLCRLCPWDWTFFNGNCYFFSKSQRDWHDSMTACKEMGAQLVIIKSHEEQSFLQQTSKKNSYTWMGLSDLNKEGEWYWLDGSPLSDSFEKYWKKGQPNNVGGQDCVEFRDNGWNDAKCEQRKFWICKKIATTCLSKW", "length": 208 }, "evidence": [ { "id": "HGNC:1641", "url": "https://alliancegenome.org/gene/HGNC:1641#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q91ZW8-1", "protein_name": "CD209 antigen-like protein D", "gene_name": "Cd209d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDSMESKTQQVVIPEDEECLMSGTRYSDISSRLQTKFGIKSLAEYTKQSRNPLVLQLLSFLFLAGLLLIILILVSKVPSSEVQNKIYQELMQLKAEVHDGLCQPCARDWTFFNGSCYFFSKSQRNWHNSTTACQELGAQLVIIETDEEQTFLQQTSKARGPTWMGLSDMHNEATWHWVDGSPLSPSFTRYWNRGEPNNVGDEDCAEFSGDGWNDLSCDKLLFWICKKVSTSSCTTK", "length": 237 }, "evidence": [ { "id": "MGI:2157947", "url": "https://alliancegenome.org/gene/MGI:2157947#orthology", "database": "AGR" }, { "id": "HGNC:1641", "url": "https://alliancegenome.org/gene/HGNC:1641#orthology", "database": "AGR" }, { "id": "FB:FBgn0040104", "url": "https://alliancegenome.org/gene/FB:FBgn0040104#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q91ZW9-1", "protein_name": "CD209 antigen-like protein C", "gene_name": "Cd209c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRMHTRLQFLKRVSNVAYSHGQEQAKKEKVYKEMTQLKSQINRLCRPCPWDWTVFQGNCYFFSKFQQNWNDSVNACRKLDAQLVVIKSDDEQSFLQQTSKEKGYAWMGLSDLKHEGRWHWVDGSHLLFSFMKYWNKGEPNNEWEEDCAEFRGDGWNDAPCTIKKYWICKKSAMSCTEK", "length": 178 }, "evidence": [ { "id": "HGNC:1641", "url": "https://alliancegenome.org/gene/HGNC:1641#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q91ZX1-1", "protein_name": "CD209 antigen-like protein A", "gene_name": "Cd209a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDSKEMGKRQLRPLDEELLTSSHTRHSIKGFGFQTNSGFSSFTGCLVHSQVPLALQVLFLAVCSVLLVVILVKVYKIPSSQEENNQMNVYQELTQLKAGVDRLCRSCPWDWTHFQGSCYFFSVAQKSWNDSATACHNVGAQLVVIKSDEEQNFLQQTSKKRGYTWMGLIDMSKESTWYWVDGSPLTLSFMKYWSKGEPNNLGEEDCAEFRDDGWNDTKCTNKKFWICKKLSTSCPSK", "length": 238 }, "evidence": [ { "id": "HGNC:1641", "url": "https://alliancegenome.org/gene/HGNC:1641#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H2X3-1", "protein_name": "C-type lectin domain family 4 member M", "gene_name": "CLEC4M", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSDSKEPRVQQLGLLEEDPTTSGIRLFPRDFQFQQIHGHKSSTGCLGHGALVLQLLSFMLLAGVLVAILVQVSKVPSSLSQEQSEQDAIYQNLTQLKAAVGELSEKSKLQEIYQELTQLKAAVGELPEKSKLQEIYQELTRLKAAVGELPEKSKLQEIYQELTRLKAAVGELPEKSKLQEIYQELTRLKAAVGELPEKSKLQEIYQELTELKAAVGELPEKSKLQEIYQELTQLKAAVGELPDQSKQQQIYQELTDLKTAFERLCRHCPKDWTFFQGNCYFMSNSQRNWHDSVTACQEVRAQLVVIKTAEEQNFLQLQTSRSNRFSWMGLSDLNQEGTWQWVDGSPLSPSFQRYWNSGEPNNSGNEDCAEFSGSGWNDNRCDVDNYWICKKPAACFRDE", "length": 399 }, "evidence": [ { "id": "MGI:2157947", "url": "https://alliancegenome.org/gene/MGI:2157947#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JKF4-1", "protein_name": "C-type lectin domain family 6 member A", "gene_name": "Clec6a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVQERQSQGKGVCWTLRLWSAAVISMLLLSTCFIASCVVTYQFIMDQPSRRLYELHTYHSSLTCFSEGTMVSEKMWGCCPNHWKSFGSSCYLISTKENFWSTSEQNCVQMGAHLVVINTEAEQNFITQQLNESLSYFLGLSDPQGNGKWQWIDDTPFSQNVRFWHPHEPNLPEERCVSIVYWNPSKWGWNDVFCDSKHNSICEMKKIYL", "length": 209 }, "evidence": [ { "id": "MGI:1861231", "url": "https://alliancegenome.org/gene/MGI:1861231#orthology", "database": "AGR" }, { "id": "FB:FBgn0040104", "url": "https://alliancegenome.org/gene/FB:FBgn0040104#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NNX6-1", "protein_name": "CD209 antigen", "gene_name": "CD209", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSDSKEPRLQQLGLLEEEQLRGLGFRQTRGYKSLAGCLGHGPLVLQLLSFTLLAGLLVQVSKVPSSISQEQSRQDAIYQNLTQLKAAVGELSEKSKLQEIYQELTQLKAAVGELPEKSKLQEIYQELTRLKAAVGELPEKSKLQEIYQELTWLKAAVGELPEKSKMQEIYQELTRLKAAVGELPEKSKQQEIYQELTRLKAAVGELPEKSKQQEIYQELTRLKAAVGELPEKSKQQEIYQELTQLKAAVERLCHPCPWEWTFFQGNCYFMSNSQRNWHDSITACKEVGAQLVVIKSAEEQNFLQLQSSRSNRFTWMGLSDLNQEGTWQWVDGSPLLPSFKQYWNRGEPNNVGEEDCAEFSGNGWNDDKCNLAKFWICKKSAASCSRDEEQFLSPAPATPNPPPA", "length": 404 }, "evidence": [ { "id": "MGI:2157947", "url": "https://alliancegenome.org/gene/MGI:2157947#orthology", "database": "AGR" }, { "id": "HGNC:1641", "url": "https://alliancegenome.org/gene/HGNC:1641#orthology", "database": "AGR" }, { "id": "FB:FBgn0040104", "url": "https://alliancegenome.org/gene/FB:FBgn0040104#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QZ15-1", "protein_name": "C-type lectin domain family 4 member A", "gene_name": "Clec4a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASEITYAEVKFKNESNSLHTYSESPAAPREKPIRDLRKPGSPSLLLTSLMLLLLLLAITFLVAFIIYFQKYSQLLEEKKAAKNIMHNELNCTKSVSPMEDKVWSCCPKDWRLFGSHCYLVPTVSSSASWNKSEENCSRMGAHLVVIQSQEEQDFITGILDTHAAYFIGLWDTGHRQWQWVDQTPYEESITFWHNGEPSSGNEKCATIIYRWKTGWGWNDISCSLKQKSVCQMKKINL", "length": 238 }, "evidence": [ { "id": "HGNC:13257", "url": "https://alliancegenome.org/gene/HGNC:13257#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9R0Q8-1", "protein_name": "C-type lectin domain family 4 member E", "gene_name": "Clec4e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSTKSPASHHTERGCFKNSQVLSWTIAGASILFLSGCFITRCVVTYRSSQISGQNLQPHRNIKELSCYSEASGSVKNCCPLNWKHYQSSCYFFSTTTLTWSSSLKNCSDMGAHLVVIDTQEEQEFLFRTKPKRKEFYIGLTDQVVEGQWQWVDDTPFTESLSFWDAGEPNNIVLVEDCATIRDSSNSRKNWNDIPCFYSMPWICEMPEISPLD", "length": 214 }, "evidence": [ { "id": "MGI:1861232", "url": "https://alliancegenome.org/gene/MGI:1861232#orthology", "database": "AGR" }, { "id": "FB:FBgn0040104", "url": "https://alliancegenome.org/gene/FB:FBgn0040104#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UJ71-1", "protein_name": "C-type lectin domain family 4 member K", "gene_name": "CD207", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTVEKEAPDAHFTVDKQNISLWPREPPPKSGPSLVPGKTPTVRAALICLTLVLVASVLLQAVLYPRFMGTISDVKTNVQLLKGRVDNISTLDSEIKKNSDGMEAAGVQIQMVNESLGYVRSQFLKLKTSVEKANAQIQILTRSWEEVSTLNAQIPELKSDLEKASALNTKIRALQGSLENMSKLLKRQNDILQVVSQGWKYFKGNFYYFSLIPKTWYSAEQFCVSRNSHLTSVTSESEQEFLYKTAGGLIYWIGLTKAGMEGDWSWVDDTPFNKVQSVRFWIPGEPNNAGNNEHCGNIKAPSLQAWNDAPCDKTFLFICKRPYVPSEP", "length": 328 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-090313-154", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-154#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9ULY5-1", "protein_name": "C-type lectin domain family 4 member E", "gene_name": "CLEC4E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNSSKSSETQCTERGCFSSQMFLWTVAGIPILFLSACFITRCVVTFRIFQTCDEKKFQLPENFTELSCYNYGSGSVKNCCPLNWEYFQSSCYFFSTDTISWALSLKNCSAMGAHLVVINSQEEQEFLSYKKPKMREFFIGLSDQVVEGQWQWVDGTPLTKSLSFWDVGEPNNIATLEDCATMRDSSNPRQNWNDVTCFLNYFRICEMVGINPLNKGKSL", "length": 219 }, "evidence": [ { "id": "MGI:1861232", "url": "https://alliancegenome.org/gene/MGI:1861232#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9UMR7-1", "protein_name": "C-type lectin domain family 4 member A", "gene_name": "CLEC4A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSEITYAEVRFKNEFKSSGINTASSAASKERTAPHKSNTGFPKLLCASLLIFFLLLAISFFIAFVIFFQKYSQLLEKKTTKELVHTTLECVKKNMPVEETAWSCCPKNWKSFSSNCYFISTESASWQDSEKDCARMEAHLLVINTQEEQDFIFQNLQEESAYFVGLSDPEGQRHWQWVDQTPYNESSTFWHPREPSDPNERCVVLNFRKSPKRWGWNDVNCLGPQRSVCEMMKIHL", "length": 237 }, "evidence": [ { "id": "HGNC:13257", "url": "https://alliancegenome.org/gene/HGNC:13257#orthology", "database": "AGR" }, { "id": "FB:FBgn0040104", "url": "https://alliancegenome.org/gene/FB:FBgn0040104#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VIX1-1", "protein_name": "Galactose-specific C-type lectin, isoform A", "gene_name": "Lectin-galC1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLKLTVLLITLLVIAKTGWTREKFSIQVNEGNTFGALVKAEPFTKINDGYYFFGTESLNWYEAYEKCRELNSELVTFETDQEFDAVTAFLTANGSRLTYWTSGNDLAKTGSHRWFTNAQRISSLRWARNQPDNAGQKEHCIHLGYIYKDSRKFELNDRPCSQDPNSLFKYICEAPEMETISIVVWK", "length": 186 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-090313-154", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-154#orthology", "database": "AGR" }, { "id": "MGI:1917442", "url": "https://alliancegenome.org/gene/MGI:1917442#orthology", "database": "AGR" }, { "id": "MGI:1916392", "url": "https://alliancegenome.org/gene/MGI:1916392#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VKL8-1", "protein_name": "Lectin-33A", "gene_name": "lectin-33A", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MCIKGSFGFLLIALILECANAQTCPLPFSRVGNKCYHVSLQEANWHVADRSCRKLGAELMVLDNQEDKLLTTTFLKSMGLSFTQSWHHSVWAGINCLGNRRTFLLARNGETVPYLNWVPLEPNNASPEEDCVGFANYNGAFGYHDIECKVQFPYVCQREPAEDYLCLKRDLFLKVLL", "length": 177 }, "evidence": [ { "id": "MGI:2157947", "url": "https://alliancegenome.org/gene/MGI:2157947#orthology", "database": "AGR" }, { "id": "HGNC:13257", "url": "https://alliancegenome.org/gene/HGNC:13257#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VLM0-1", "protein_name": "Lectin-29Ca", "gene_name": "lectin-29Ca", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MYKYATCIFSIFALWNFWGVSAKKQDTSTGTNELPKAPMPYYTIENIDMHQQHWFTYNSLRQNGTLWRIGNMEQRLEMRLQSFQNQMETKLRALKQQIEPYMENVKMSNKIKMSVFKKIGSRHFYLEKQKKMPWDSAYDTCRQMGGHLANILDEKELNEIFSEETKKKYWVDINSRANDGASWISTLSGRDVPFLKWKPNLATNIHNHCVYINSNEMYFENCANDNYFACQAEQWA", "length": 236 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-090313-154", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-154#orthology", "database": "AGR" }, { "id": "MGI:1917442", "url": "https://alliancegenome.org/gene/MGI:1917442#orthology", "database": "AGR" }, { "id": "MGI:1916392", "url": "https://alliancegenome.org/gene/MGI:1916392#orthology", "database": "AGR" }, { "id": "MGI:1861232", "url": "https://alliancegenome.org/gene/MGI:1861232#orthology", "database": "AGR" }, { "id": "MGI:1861231", "url": "https://alliancegenome.org/gene/MGI:1861231#orthology", "database": "AGR" }, { "id": "MGI:2157947", "url": "https://alliancegenome.org/gene/MGI:2157947#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VM16-1", "protein_name": "C-type lectin domain-containing protein", "gene_name": "Dmel\\CG15818", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFSSTRIILCAFLLLYPYGSLIEAQEGRRYVCLLSDPPNQCSEYCVSALQPVIDHLSKEQQDWGACEVKLNGSVAKLDKIEDQLTATQIQIEAQQAFLVNNISKAIKTEDLEQKLKDIEGNQTALSNQLKDGQKRTENQLTAIQKTLSDIERKLVLQRYQQIGSRYFYIEHNLQVNWRTAEQRCIEMGGHLAAFQNAEEYNAIVGQLNKANYWLGVNDLAKQGEFISLASGKRATYFKWRKNEPKYNNPTQHCAYVFGHENIMIVLSCTTDVMHFICQSDSDV", "length": 283 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-090313-154", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-154#orthology", "database": "AGR" }, { "id": "MGI:1917442", "url": "https://alliancegenome.org/gene/MGI:1917442#orthology", "database": "AGR" }, { "id": "MGI:1916392", "url": "https://alliancegenome.org/gene/MGI:1916392#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-285", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-285#orthology", "database": "AGR" }, { "id": "MGI:1861232", "url": "https://alliancegenome.org/gene/MGI:1861232#orthology", "database": "AGR" }, { "id": "MGI:1861231", "url": "https://alliancegenome.org/gene/MGI:1861231#orthology", "database": "AGR" }, { "id": "MGI:2157947", "url": "https://alliancegenome.org/gene/MGI:2157947#orthology", "database": "AGR" }, { "id": "RGD:1597482", "url": "https://alliancegenome.org/gene/RGD:1597482#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VPS1-1", "protein_name": "Lectin-21Cb", "gene_name": "lectin-21Cb", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFKYDTYFLYLIVLLDPQGAQENNCPKVSLSERLEKRGEFSLVEFDPLLKFIVKNPHKELLGEIEGLVGHTENKLQPMKSVIPNQSKALLNYLDLHSKLEYLDAALQKAINSLQCSLKNTKVMSTGKPHPEFQKLGSRYFYIERHVRQNWFDAADKCRRMGGHLATPQDEDELYLIRKQLEARWFWLDISNLVDKDQYISLATGKEVSYLKWRHGEPKKSSTANCAYLYAGDYYTYQCSDRNFFICQAV", "length": 249 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-090313-154", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-154#orthology", "database": "AGR" }, { "id": "MGI:1917442", "url": "https://alliancegenome.org/gene/MGI:1917442#orthology", "database": "AGR" }, { "id": "MGI:1916392", "url": "https://alliancegenome.org/gene/MGI:1916392#orthology", "database": "AGR" }, { "id": "MGI:1861232", "url": "https://alliancegenome.org/gene/MGI:1861232#orthology", "database": "AGR" }, { "id": "MGI:1861231", "url": "https://alliancegenome.org/gene/MGI:1861231#orthology", "database": "AGR" }, { "id": "MGI:2157947", "url": "https://alliancegenome.org/gene/MGI:2157947#orthology", "database": "AGR" }, { "id": "MGI:109515", "url": "https://alliancegenome.org/gene/MGI:109515#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VPS2-1", "protein_name": "Lectin-21Ca", "gene_name": "lectin-21Ca", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFQHANFFLHVFMACGLYGIRAKDVCPRMSTDKEVCLVELAPVLKYISNNHKSHWNSANEVQVNETRKQLAKIEGQEKETNDKIKVIHDNVDNEFNALSAKIKNVKNIQRHLASLELQLQETKKALNLSVEAKKVMPKTEIPSQFQKIGWRHFFIEKKHKVDWFKATSMCHKMGAHLLTIQSEDELDAIRTELKDINDGSHDFWLDINDIAKWGEFISLATGMNPPFLKWHKHRPQVQIHQRCVHLRGGEMMDGKCSEQFLFICQLAVN", "length": 269 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-090313-154", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-154#orthology", "database": "AGR" }, { "id": "MGI:1917442", "url": "https://alliancegenome.org/gene/MGI:1917442#orthology", "database": "AGR" }, { "id": "MGI:1916392", "url": "https://alliancegenome.org/gene/MGI:1916392#orthology", "database": "AGR" }, { "id": "MGI:1861232", "url": "https://alliancegenome.org/gene/MGI:1861232#orthology", "database": "AGR" }, { "id": "MGI:1861231", "url": "https://alliancegenome.org/gene/MGI:1861231#orthology", "database": "AGR" }, { "id": "MGI:2157947", "url": "https://alliancegenome.org/gene/MGI:2157947#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VQ53-1", "protein_name": "C-type lectin domain-containing protein", "gene_name": "mdcds_4396", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MQKLSIWLLLALFAWNAHAPSAAMPSVCLLQDAPQQCGEFCLTALSPMLDHIARHEGEWTSSVLQANATEARLARIETLQTAMNIRQKVLQEGFPKDIVARLDRLESQQAALLRILSKFDRKIVAPKFELIGSRFFYIEDETRRNWTSAGSACRQMGTQLATIRSAEELAALRAKLNKERHYWLDITDLEKEGDFRISASGKRPNFLKWRAGQPNNFSGNQHCVDLLDGLMYDNKCESLSYFICQSDDDSLD", "length": 252 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-285", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-285#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VQX3-1", "protein_name": "Lectin-24Db", "gene_name": "lectin-24Db", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFRLEKCIVYLLVACNLVESRAESTENSRSVCLLKDPPNQCGEFCLSVLQPLLDHIVKHQEQWNTSEALWLNETQGKLDRIQTQLAAQALSLEESAQKVPGDIKDRLDRMEHLQTTLQESLKKMPAELDARLMKMENQQKTLGDQLENQINLTKESQQDQLEALKNAMPINFEMRLAQIEEQQKLLQETLKKIPEDFERKLQKLEQNQKDELTKLGAQQSANQVTLKEIYTKVFWPKFERIGSRLFYINHKDAYDWQSAVDFCRDMGGYIAAIKDQEELDAISARLDDKSYWLGINDLQSSNTYVSVASGREVEFLNWNAGEPNHGNEDENCVELIRSKMNDDPCHRKKHVICQTDKEV", "length": 359 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-090313-154", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-154#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-285", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-285#orthology", "database": "AGR" }, { "id": "RGD:1597482", "url": "https://alliancegenome.org/gene/RGD:1597482#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q9VQU4", "url": "https://www.uniprot.org/uniprotkb/Q9VQU4" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "Q9VQU4", "url": "https://www.uniprot.org/uniprotkb/Q9VQU4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "Q9VQU4", "url": "https://www.uniprot.org/uniprotkb/Q9VQU4" } ], "pmid": "" }, { "name": "calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules", "id": "GO:0016339", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016339", "evidence": [ { "database": "UniProtKB", "id": "Q9VQU4", "url": "https://www.uniprot.org/uniprotkb/Q9VQU4" } ], "pmid": "" }, { "name": "induction of bacterial agglutination", "id": "GO:0043152", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043152", "evidence": [ { "database": "UniProtKB", "id": "Q9VQU4", "url": "https://www.uniprot.org/uniprotkb/Q9VQU4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "Q9VQU4", "url": "https://www.uniprot.org/uniprotkb/Q9VQU4" } ], "pmid": "" }, { "name": "pattern recognition receptor activity", "id": "GO:0038187", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038187", "evidence": [ { "database": "UniProtKB", "id": "Q9VQU4", "url": "https://www.uniprot.org/uniprotkb/Q9VQU4" } ], "pmid": "" }, { "name": "galactose binding", "id": "GO:0005534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005534", "evidence": [ { "database": "UniProtKB", "id": "Q9VQU4", "url": "https://www.uniprot.org/uniprotkb/Q9VQU4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 269, "end_pos": 271, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VQU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQU4" }, { "id": "PS50041", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50041" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C-type lectin", "eco_id": "ECO_0000259", "start_pos": 165, "end_pos": 279, "start_aa": "Ile", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 269, "end_pos": 271 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VQW4-1", "uniprot_ac": "Q9VQW4", "uniprot_id": "Q9VQW4_DROME", "mass": { "chemical_mass": 11979.0, "monoisotopic_mass": 11979.0 }, "refseq": { "ac": "NP_608814", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608814" }, "gene_names": [ { "name": "Dmel\\CG15422", "type": "recommended", "evidence": [ { "id": "Q9VQW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQW4" } ] }, { "name": "CG15422", "type": "synonym", "evidence": [ { "id": "NP_608814", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608814" }, { "id": "Q9VQW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQW4" } ] }, { "name": "Dmel\\CG15422", "type": "synonym", "evidence": [ { "id": "NP_608814", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608814" } ] }, { "name": "Dmel_CG15422", "type": "synonym", "evidence": [ { "id": "Q9VQW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQW4" } ] } ], "protein_names": [ { "name": "CG15422-PA", "type": "synonym", "evidence": [ { "id": "NP_608814", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608814" } ] }, { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "Q9VQW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQW4/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_608814", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608814" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VQW4", "url": "https://www.uniprot.org/uniprotkb/Q9VQW4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG15422", "url": "https://www.uniprot.org/uniprotkb/Q9VQW4", "locus": { "chromosome": "2L", "start_pos": 4005670, "end_pos": 4004984, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0031579", "url": "https://www.ensemblgenomes.org/id/FBgn0031579" } ] } } ], "crossref": [ { "id": "FB:FBgn0031579", "url": "https://alliancegenome.org/gene/FB:FBgn0031579", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0031579", "url": "https://bgee.org/?page=gene&gene_id=FBgn0031579", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0031579", "url": "https://flybase.org/reports/FBgn0031579", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "33615", "url": "https://www.ncbi.nlm.nih.gov/gene/33615", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VQW4", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VQW4*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "dme:Dmel_CG15422", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG15422", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YYEDPCG", "url": "https://omabrowser.org/oma/group/YYEDPCG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VQW4", "url": "https://www.orthodb.org/?gene=Q9VQW4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "NP_608814", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608814", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VQW4", "url": "https://www.uniprot.org/uniprotkb/Q9VQW4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VQW4-1", "url": "https://www.uniprot.org/uniprotkb/Q9VQW4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRYYEDPCGYPPRHHHGRPNIEIDVVPGWGGGYYPPPPPPRPAEVVYMTPAATYVPGTQVIMPQPYGGVTVATTNGYYPQQQQQAYEYQYQYQQPYNNPPYPQW", "length": 104, "header": "tr|Q9VQW4-1|Q9VQW4_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG15422 PE=1 SV=1 CANONICAL=Q9VQW4-1" }, "isoforms": [ { "isoform_ac": "Q9VQW4-1", "url": "https://www.uniprot.org/uniprotkb/Q9VQW4/entry#Q9VQW4-1", "sequence": { "sequence": "MRYYEDPCGYPPRHHHGRPNIEIDVVPGWGGGYYPPPPPPRPAEVVYMTPAATYVPGTQVIMPQPYGGVTVATTNGYYPQQQQQAYEYQYQYQQPYNNPPYPQW", "length": 104, "header": "tr|Q9VQW4-1|Q9VQW4_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG15422 PE=1 SV=1 CANONICAL=Q9VQW4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VQW4", "url": "https://www.uniprot.org/uniprotkb/Q9VQW4" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VQW4", "url": "https://www.uniprot.org/uniprotkb/Q9VQW4" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQW4", "url": "https://www.uniprot.org/uniprotkb/Q9VQW4" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQW4", "url": "https://www.uniprot.org/uniprotkb/Q9VQW4" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VQW4", "url": "https://www.uniprot.org/uniprotkb/Q9VQW4" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VQW4", "url": "https://www.uniprot.org/uniprotkb/Q9VQW4" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VQW4", "url": "https://www.uniprot.org/uniprotkb/Q9VQW4" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQW4", "url": "https://www.uniprot.org/uniprotkb/Q9VQW4" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQW4", "url": "https://www.uniprot.org/uniprotkb/Q9VQW4" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VQW4", "url": "https://www.uniprot.org/uniprotkb/Q9VQW4" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VQW4", "url": "https://www.uniprot.org/uniprotkb/Q9VQW4" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG15422", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG15422", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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12275.0 }, "refseq": { "ac": "NP_608815", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608815" }, "gene_names": [ { "name": "Dmel\\CG15423", "type": "recommended", "evidence": [ { "id": "Q9VQW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQW5" } ] }, { "name": "CG15423", "type": "synonym", "evidence": [ { "id": "NP_608815", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608815" }, { "id": "Q9VQW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQW5" } ] }, { "name": "Dmel\\CG15423", "type": "synonym", "evidence": [ { "id": "NP_608815", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608815" } ] }, { "name": "Dmel_CG15423", "type": "synonym", "evidence": [ { "id": "Q9VQW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQW5" } ] } ], "protein_names": [ { "name": "CG15423-PA", "type": "synonym", "evidence": [ { "id": "NP_608815", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608815" } ] }, { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "Q9VQW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQW5/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_608815", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608815" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VQW5", "url": "https://www.uniprot.org/uniprotkb/Q9VQW5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG15423", "url": "https://www.uniprot.org/uniprotkb/Q9VQW5", "locus": { "chromosome": "2L", "start_pos": 4006606, "end_pos": 4006041, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0031580", "url": "https://www.ensemblgenomes.org/id/FBgn0031580" } ] } } ], "crossref": [ { "id": "FB:FBgn0031580", "url": "https://alliancegenome.org/gene/FB:FBgn0031580", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0031580", "url": "https://bgee.org/?page=gene&gene_id=FBgn0031580", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0031580", "url": "https://flybase.org/reports/FBgn0031580", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "33616", "url": "https://www.ncbi.nlm.nih.gov/gene/33616", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VQW5", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VQW5*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "dme:Dmel_CG15423", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG15423", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CVEVIQP", "url": "https://omabrowser.org/oma/group/CVEVIQP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VQW5", "url": "https://www.orthodb.org/?gene=Q9VQW5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "NP_608815", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608815", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VQW5", "url": "https://www.uniprot.org/uniprotkb/Q9VQW5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VQW5-1", "url": "https://www.uniprot.org/uniprotkb/Q9VQW5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPYYEEERRHHHHHHHGGRPIVEVDIVPPRIPRPVIEIGVGGRYPPPPPRVEVITPAAVYQPPPPRPIIEVDVVPPRAPFIEFNIGGRRPPPREEVIIVQQPPPPRW", "length": 107, "header": "tr|Q9VQW5-1|Q9VQW5_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG15423 PE=4 SV=1 CANONICAL=Q9VQW5-1" }, "isoforms": [ { "isoform_ac": "Q9VQW5-1", "url": "https://www.uniprot.org/uniprotkb/Q9VQW5/entry#Q9VQW5-1", "sequence": { "sequence": "MPYYEEERRHHHHHHHGGRPIVEVDIVPPRIPRPVIEIGVGGRYPPPPPRVEVITPAAVYQPPPPRPIIEVDVVPPRAPFIEFNIGGRRPPPREEVIIVQQPPPPRW", "length": 107, "header": "tr|Q9VQW5-1|Q9VQW5_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG15423 PE=4 SV=1 CANONICAL=Q9VQW5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, 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"MFRLEKCIVYLLVACNLVESRAESTENSRSVCLLKDPPNQCGEFCLSVLQPLLDHIVKHQEQWNTSEALWLNETQGKLDRIQTQLAAQALSLEESAQKVPGDIKDRLDRMEHLQTTLQESLKKMPAELDARLMKMENQQKTLGDQLENQINLTKESQQDQLEALKNAMPINFEMRLAQIEEQQKLLQETLKKIPEDFERKLQKLEQNQKDELTKLGAQQSANQVTLKEIYTKVFWPKFERIGSRLFYINHKDAYDWQSAVDFCRDMGGYIAAIKDQEELDAISARLDDKSYWLGINDLQSSNTYVSVASGREVEFLNWNAGEPNHGNEDENCVELIRSKMNDDPCHRKKHVICQTDKEV", "length": 359, "header": "tr|Q9VQX3-1|Q9VQX3_DROME Isoform 1 of Lectin-24Db OS=Drosophila melanogaster OX=7227 GN=lectin-24Db PE=4 SV=1 CANONICAL=Q9VQX3-1" }, "isoforms": [ { "isoform_ac": "Q9VQX3-1", "url": "https://www.uniprot.org/uniprotkb/Q9VQX3/entry#Q9VQX3-1", "sequence": { "sequence": "MFRLEKCIVYLLVACNLVESRAESTENSRSVCLLKDPPNQCGEFCLSVLQPLLDHIVKHQEQWNTSEALWLNETQGKLDRIQTQLAAQALSLEESAQKVPGDIKDRLDRMEHLQTTLQESLKKMPAELDARLMKMENQQKTLGDQLENQINLTKESQQDQLEALKNAMPINFEMRLAQIEEQQKLLQETLKKIPEDFERKLQKLEQNQKDELTKLGAQQSANQVTLKEIYTKVFWPKFERIGSRLFYINHKDAYDWQSAVDFCRDMGGYIAAIKDQEELDAISARLDDKSYWLGINDLQSSNTYVSVASGREVEFLNWNAGEPNHGNEDENCVELIRSKMNDDPCHRKKHVICQTDKEV", "length": 359, "header": "tr|Q9VQX3-1|Q9VQX3_DROME Isoform 1 of Lectin-24Db OS=Drosophila melanogaster OX=7227 GN=lectin-24Db PE=4 SV=1 CANONICAL=Q9VQX3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VQX3", "url": "https://www.uniprot.org/uniprotkb/Q9VQX3" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VQX3", "url": "https://www.uniprot.org/uniprotkb/Q9VQX3" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQX3", "url": "https://www.uniprot.org/uniprotkb/Q9VQX3" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQX3", "url": "https://www.uniprot.org/uniprotkb/Q9VQX3" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VQX3", "url": "https://www.uniprot.org/uniprotkb/Q9VQX3" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VQX3", "url": "https://www.uniprot.org/uniprotkb/Q9VQX3" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VQX3", "url": "https://www.uniprot.org/uniprotkb/Q9VQX3" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQX3", "url": "https://www.uniprot.org/uniprotkb/Q9VQX3" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VQX3", "url": "https://www.uniprot.org/uniprotkb/Q9VQX3" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VQX3", "url": "https://www.uniprot.org/uniprotkb/Q9VQX3" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VQX3", "url": "https://www.uniprot.org/uniprotkb/Q9VQX3" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG2958", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG2958", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JU13-1", "protein_name": "C-type lectin domain family 4, member G", "gene_name": "Clec4g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNTGGYSKLGGVIEEAPRGQLGRWECYKERLFFLVLAFLVATVLWALILSILLSNASSQLRVLLNHQDLLRTNASKQKVMLSSLKDDVGACRNCCSVMKAQLQTTLAEFKDTQAKVMEQESNLKDLQERVTQDLAKASRDRENIRSELFRALETVKRQNSSCEQCPPSWLPFQGSCYYFSETQAIWDTAQSYCVGQGAHLVIVRDLNEQGFLSQHTRGRGYWLGLRADRRLNKIQGYRWVDGAPLTFSHWNSGEPNDSRGHEDCVMMLHSGLWNDAPCANERDGWICEKRSSC", "length": 293 }, "evidence": [ { "id": "RGD:1597482", "url": "https://alliancegenome.org/gene/RGD:1597482#orthology", "database": "AGR" }, { "id": "FB:FBgn0040102", "url": "https://alliancegenome.org/gene/FB:FBgn0040102#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A230-1", "protein_name": "CD209a molecule like 3", "gene_name": "Cd209al3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQCQVREGPNLEGLRRCMIMCIQAFIYPDPPLPIDSLCRPCPWEWTFFHGRCYYFSKSQRNWNDSVAACQEVDAQLVTVESDEEQTFLDTFLKNKGPAWMGLSDLKQESTWQWVDGSPLSDSFRKYWIKGEPNNQGNEDCAELREDGWNDNKCDNKKFWICKKPETSCSSK", "length": 171 }, "evidence": [ { "id": "HGNC:13523", "url": "https://alliancegenome.org/gene/HGNC:13523#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M1RLL2-1", "protein_name": "Uncharacterized protein dcsignlg", "gene_name": "dcsignlg", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEAVYENVECRDIKNSTGPQSQNHNRDEENDRKRRRWKCVVLVIMGLICALLLLFITLQNISITAERDLFKTYKNTVEELNHTISSLQHDNTDLETDKQQLEDKYNSLSLKKQQLETKYNSLSLGKQQLENRVTSLSAELKEARSKSGWFFMSTEAMSWSESRQFCRDRGADLVIIKSEEKQRFISSLVKEDTWIGLSVTETGGNKWKWVDNSPLNQGFWAKGEPNNYQGAKEDCVEVRISQGTPNNWNDRRCSDSRKAVCEK", "length": 263 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-090313-154", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-154#orthology", "database": "AGR" }, { "id": "FB:FBgn0040102", "url": "https://alliancegenome.org/gene/FB:FBgn0040102#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PGK7-1", "protein_name": "Immune-related, lectin-like receptor 3 isoform X1", "gene_name": "illr3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGSVYENSVFAFSTGNSDENDSQYKGHFSNYRESKREVNTAKWTKVLLIVFAVSLVFALGGLCAVRIQYVSVSAQLSAQETNGTIMSRQLDKLTANFTTVRDHLHINELLMKELTANYSRVKEQLSISEETVRKLSRFNQSSGCAICAIHWTHSGEKCYYFSTVKMNWTQSRDHCVTKGGHLVIITSQAEQEFLTSNVKETHWIGLNDLDTEGRWLWVDNQPLSQTEEFWMKRENGVSEPDNWTKQHVDGEDCASLGHPDGETDFWTDAYCFEEKRFVCEAAAAV", "length": 285 }, "evidence": [ { "id": "HGNC:14556", "url": "https://alliancegenome.org/gene/HGNC:14556#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9Q0P0-1", "protein_name": "Uncharacterized protein hbl1 isoform X1", "gene_name": "hbl1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTRIHAWRRGVYSKKTPFSSHVGNFSFVVFVRSLKERLSIEAQMALLKLFLGALLLLQLVLQLLAGAADPQTLNCPAYAGVPGTPGHNGLPGRDGRDGRDGVTGPKGEKGEPGVSVQGPPGKAGPPGPDGAQGESGPPGSPGSESVIESLKSEIQNLKAKIDTIEKAASFSNFRKVGQKYYVTDRIFGTFDNGIKLCESSSGTLVVPKSSAENQALVRVAASSGLINEKPYIGVTDKETEGQFVDIEGKQLTFTKWGPGQPDDYQGAQDCGVIDVSGTWDDGNCGDIRPIICEIDIK", "length": 297 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-285", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-285#orthology", "database": "AGR" }, { "id": "FB:FBgn0040102", "url": "https://alliancegenome.org/gene/FB:FBgn0040102#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TFP3-1", "protein_name": "Uncharacterized protein zmp:0000000937 isoform X1", "gene_name": "zmp:0000000937", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTSGIEMAQPIYGNILVNYDPTPKMDRCSLRNETASDSGKKRSSRAAPVCLVLLCLLLLTAVIVLSVFIYTNNTNFAEERRQLITNIANITEDRDKLLTDIINLTKIKDKVLINITNLEEDRDELLNKITTFTKARNEILKKNANLLKDKDQLIKQLQVFGQEAYYQSSFYYLSSERKSWTESRRDCKDRGADLIIINNKQEQDFIMKITSNNEFWIGLTDSDKEGIWKWVDGSNLTSRFWASSGSITEPNGRKTENCAVTHLKKHPELIGWLDVACDGAYQWICEKNILPVTS", "length": 294 }, "evidence": [ { "id": "RGD:1561466", "url": "https://alliancegenome.org/gene/RGD:1561466#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TVV3-1", "protein_name": "Asialoglycoprotein receptor 2", "gene_name": "asgr1c.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRRGWSLFFNFKNQPLILVPLFLLSQNMEMHSSEEYMKMEVECETKQSLCKGRPCSKQTGILVLLGTVGMIIFLVLISIIVQAKKLSDIETLMTDLSSSLDSLTSKHEENQQKLERQQNVSYIQVKKQMDTVRASVSSIMSKLKADSVRTSFMFRHPLERFLIEHSSEELESGCSDSAWVPFGNSCYLFSRDKMNWTEAKDYCEEKGAWLLKIEDDSEDEWQFVTDFANPTHYWIGLTDQNTGQWRWADGTNYTMNKEHWGPGQPDEWTEHSLGEEGEDCAEITYESLLNDLHCSSKIKFICEMKT", "length": 306 }, "evidence": [ { "id": "HGNC:743", "url": "https://alliancegenome.org/gene/HGNC:743#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A9C461-1", "protein_name": "Asialoglycoprotein receptor-like 1", "gene_name": "asgrl1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKTAIRTLTAADEQKSPHKLTLYNMETVSYDRFTSAETEINHSGQKFIMQSDCFLFPSTGRRNRMIYIIYAILALYVFILTLAVGIKISQISQEVADVRLYMKTFVDAPKTPQFENGHFSELVMQVPVAEQGPCQENWVFYKGSCYFQSTMKRNWKTAESNCIQKGSHLVVVNDLAELDFLSSIVKLSDSYWIGLVEKEEGQWSWVDGTEFSATEHHWDVGQPDDWDVRVNGEDCGQLHSREIVNRRRMWNDADCTLSYPYICEGNPKSH", "length": 270 }, "evidence": [ { "id": "HGNC:743", "url": "https://alliancegenome.org/gene/HGNC:743#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZCF3-1", "protein_name": "CD209e molecule", "gene_name": "Cd209e", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRIQQMGSLGFLDRSNIPLVLQLLFLILFAGLLVAIVIQVSKIPSSEEVQWEQTKQEKMYQDLSQLKSEIDSLCRLCPWDWTFFNGNCYFFSKSQRDWHNSITACQEMEAQLVTIKSPEEQSFLQQTSKKNGYTWMGLSDLNKEGEWYWLDGSPLSDSLRNYWNEGQPNNIDGQDCVEFRNDGWNDAKCDNWKFWICKKTATTCSSK", "length": 207 }, "evidence": [ { "id": "HGNC:13523", "url": "https://alliancegenome.org/gene/HGNC:13523#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZXM6-1", "protein_name": "C-type lectin domain family 6, member A, pseudogene 1", "gene_name": "Clec6a-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVQERHPQRKGVCWTLRLWSTAVISMLLLSTCFIASCMVTYQFTMEKPNRRLSELHTYHSSLTCCSKGTMVSEKLWGCCPNHWKSFGSSCYLISTKENFWSISEQNYIHMGAHLVVINTETEQNFITQQLNESLSYFLGLSDPQGNSKWQWIDNTPFSQNVRFWHPHEPNLPEEWCASIVYWNPSKWGWNDVFCDSKHNSICETKKIYL", "length": 209 }, "evidence": [ { "id": "HGNC:14556", "url": "https://alliancegenome.org/gene/HGNC:14556#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LM87-1", "protein_name": "C-type lectin domain family 4 member M", "gene_name": "Clec4m", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQPLDSMGEAGLGFWEHEDGEMEVSGSRYSIKSSRLRPNSGIKSLAGCLGHNQAPLVLQLLSFLFLAGLLLIILFQVFKTTNTQWQEEPKQEKILEELNQLTDELMSRIPISQGQNESMQEKISEQLTQLKVELLSRIPVFQVQNESMQEKISEQLTQLKAELLSKIPSLQVQDESKQEKIYQQLVQMKTELLRLCRLCPWDWTFLLGNCYFLSKSQRNWNDAVRACKEEKAQLVIINSDEEQTFLQLTSKAKGPTWMGLSDLKNEATWLWVDGSTLSSRFQKYWNRGEPNNIGEEDCVEFAGDGWNDSKCELKKFWIFKKSATACTEG", "length": 329 }, "evidence": [ { "id": "MGI:1916415", "url": "https://alliancegenome.org/gene/MGI:1916415#orthology", "database": "AGR" }, { "id": "HGNC:13523", "url": "https://alliancegenome.org/gene/HGNC:13523#orthology", "database": "AGR" }, { "id": "RGD:1561466", "url": "https://alliancegenome.org/gene/RGD:1561466#orthology", "database": "AGR" }, { "id": "FB:FBgn0040102", "url": "https://alliancegenome.org/gene/FB:FBgn0040102#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F8W3Q0-1", "protein_name": "Asialoglycoprotein receptor 1", "gene_name": "asgr1a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRVVSSDSGSVTVANTEYTDETESAETSDHTEFWRGDPSVRRLAAVPSGGRWRWCAGIAGSVAALMLLLLIITVSVNHVKFNRKFSATEVRIQNLTQIILNVISRTQELEQFGHKINADVSSLEFDQRMTETSMNNLLESAQALHDKVSELKCHIDKMRNNNTQELCCPDQWSLFSSNCYFFSTDGMSWDSARDECERKRAKLLILTSKLEKSFVVSKTKPLFYWLGLTDGRTGEWEWLDETPYEMVRSEWRPGQPDNWKAHGLGGGEDCAHFHHDGRYNDDHCSRHYRYICKAAASAI", "length": 299 }, "evidence": [ { "id": "HGNC:743", "url": "https://alliancegenome.org/gene/HGNC:743#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "M9NE79-1", "protein_name": "C-type lectin domain-containing protein", "gene_name": "Dmel\\CG43055", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFTKLTAFSAFLAIISLCRAYQISTSVIEGVASYLNTPTAPFVKIGDSYYFIENKLDRNWYDAFEACRQMNADLVAFEDRKEQKLIYHYLVDNEMDTTYWTAGTDLAEQDSFVWFSNGQPVASDLWCNNEPNNAKNEEHCVEYKPLHPEAKMGLNDRVCTFKTGYICRAPQPKTVSFIVW", "length": 180 }, "evidence": [ { "id": "MGI:1916415", "url": "https://alliancegenome.org/gene/MGI:1916415#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P07307-1", "protein_name": "Asialoglycoprotein receptor 2", "gene_name": "ASGR2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKDFQDIQQLSSEENDHPFHQGEGPGTRRLNPRRGNPFLKGPPPAQPLAQRLCSMVCFSLLALSFNILLLVVICVTGSQSEGHGGAQLQAELRSLKEAFSNFSSSTLTEVQAISTHGGSVGDKITSLGAKLEKQQQDLKADHDALLFHLKHFPVDLRFVACQMELLHSNGSQRTCCPVNWVEHQGSCYWFSHSGKAWAEAEKYCQLENAHLVVINSWEEQKFIVQHTNPFNTWIGLTDSDGSWKWVDGTDYRHNYKNWAVTQPDNWHGHELGGSEDCVEVQPDGRWNDDFCLQVYRWVCEKRRNATGEVA", "length": 311 }, "evidence": [ { "id": "HGNC:743", "url": "https://alliancegenome.org/gene/HGNC:743#orthology", "database": "AGR" }, { "id": "FB:FBgn0040102", "url": "https://alliancegenome.org/gene/FB:FBgn0040102#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P08290-1", "protein_name": "Asialoglycoprotein receptor 2", "gene_name": "Asgr2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEKDFQDIQQLDSEENDHQLIGDEEQGSHVQNLRTENPRWGGQPPSRPFPQRLCSKFRLSLLALAFNILLLVVICVVSSQSMQLQKEFWTLKETLSNFSTTTLMEFKALDSHGGSRNDNLTSWETILEKKQKDIKADHSTLLFHLKHFPLDLRTLTCQLAFFLSNGTECCPVNWVEFGGSCYWFSRDGLTWAEADQYCQMENAHLLVINSREEQEFVVKHRGAFHIWIGLTDKDGSWKWVDGTEYRSNFKNWAFTQPDNWQGHEEGGSEDCAEILSDGLWNDNFCQQVNRWACERKRDITY", "length": 301 }, "evidence": [ { "id": "HGNC:743", "url": "https://alliancegenome.org/gene/HGNC:743#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P10716-1", "protein_name": "C-type lectin domain family 4 member F", "gene_name": "Clec4f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKEAELNRDVAKFCTDNQCVILQPQGLGPKSAAPMAPRTLRHVQAIVALVVVTVFFSLLALFVVVLQPWRQKQNEDHPVKAGLHGGNYSGSDNCSQFVRRAEMQEAIQSLRASGNSSSCHKEIQTLKYQMDNVSSQVQLLGGHLEEANADIQQAKDVLKGTGALASETQALRSSLEVASADIHSLRGDLEKANAMTSQTQGLLKSSTDNTSAELHVLGRGLEEAQSEIQALRGSLQSSNDLGSRTQNFLQHSMDNISAEIQAMRDGMQRAGEEMTSLKKDLETLTAQIQNANGHLEQTDTQIQGLKAQLKSTSSLNSQIEVVNGKLKDSSRELQTLRRDLSDVSALKSNVQMLQSNLQKAKAEVQSLKTGLEATKTLAAKIQGQQSDLEALQKAVAAHTQGQKTQNQVLQLIMQDWKYFNGKFYYFSRDKKSWHEAENFCVSQGAHLASVTSQEEQAFLVQITNAVDHWIGLTDQGTEGNWRWVDGTPFDYVQSRRFWRKGQPDNWRHGNGEREDCVHLQRMWNDMACGTAYNWVCKKSTDWSVARTDQS", "length": 550 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-090313-154", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-154#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P11226-1", "protein_name": "Mannose-binding protein C", "gene_name": "MBL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLFPSLPLLLLSMVAASYSETVTCEDAQKTCPAVIACSSPGINGFPGKDGRDGTKGEKGEPGQGLRGLQGPPGKLGPPGNPGPSGSPGPKGQKGDPGKSPDGDSSLAASERKALQTEMARIKKWLTFSLGKQVGNKFFLTNGEIMTFEKVKALCVKFQASVATPRNAAENGAIQNLIKEEAFLGITDEKTEGQFVDLTGNRLTYTNWNEGEPNNAGSDEDCVLLLKNGQWNDVPCSTSHLAVCEFPI", "length": 248 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-285", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-285#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P19999-1", "protein_name": "Mannose-binding protein A", "gene_name": "Mbl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLLLPLLVLLCVVSVSSSGSQTCEETLKTCSVIACGRDGRDGPKGEKGEPGQGLRGLQGPPGKLGPPGSVGAPGSQGPKGQKGDRGDSRAIEVKLANMEAEINTLKSKLELTNKLHAFSMGKKSGKKFFVTNHERMPFSKVKALCSELRGTVAIPRNAEENKAIQEVAKTSAFLGITDEVTEGQFMYVTGGRLTYSNWKKDEPNDHGSGEDCVTIVDNGLWNDISCQASHTAVCEFPA", "length": 238 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-285", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-285#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24721-1", "protein_name": "Asialoglycoprotein receptor 2", "gene_name": "Asgr2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKDCQDIQQLDSEENDHQLSGDDEHGSHVQDPRIENPHWKGQPLSRPFPQRLCSTFRLSLLALAFNILLLVVICVVSSQSIQLQEEFRTLKETFSNFSSSTLMEFGALDTLGGSTNAILTSWLAQLEEKQQQLKADHSTLLFHLKHFPMDLRTLTCQLAYFQSNGTECCPVNWVEFGGSCYWFSRDGLTWAEADQYCQLENAHLLVINSREEQDFVVKHRSQFHIWIGLTDRDGSWKWVDGTDYRSNYRNWAFTQPDNWQGHEQGGGEDCAEILSDGHWNDNFCQQVNRWVCEKRRNITH", "length": 301 }, "evidence": [ { "id": "HGNC:743", "url": "https://alliancegenome.org/gene/HGNC:743#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P41317-1", "protein_name": "Mannose-binding protein C", "gene_name": "Mbl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSIFTSFLLLCVVTVVYAETLTEGVQNSCPVVTCSSPGLNGFPGKDGRDGAKGEKGEPGQGLRGLQGPPGKVGPTGPPGNPGLKGAVGPKGDRGDRAEFDTSEIDSEIAALRSELRALRNWVLFSLSEKVGKKYFVSSVKKMSLDRVKALCSEFQGSVATPRNAEENSAIQKVAKDIAYLGITDVRVEGSFEDLTGNRVRYTNWNDGEPNNTGDGEDCVVILGNGKWNDVPCSDSFLAICEFSD", "length": 244 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-285", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-285#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P70194-1", "protein_name": "C-type lectin domain family 4 member F", "gene_name": "Clec4f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKEAELNRDMARYCTDNQCVSLQPQGLGPKSAALMAPRTLRHVQVILALMVVTVIFSLLALFVVASQPWRPEWNKEPPSLLLRGSNNSGHDNHSQFVRETEMQVAIQRLRDYEENSSSCHKEVQILKYQMDNVSSLVQLLGSHLEDVNADILQTKDVLKESGALALETQALRSSLEVASADIHSLRGDLEKANAMTSQTRGLLKSSTENTSAELHVLGRGLEEAQSEIQALRGSLQSANDLSSQTQGFLQHSMDNISAQIQTVRDGMERAGEKMNSLKKELETLTAQTQKANGHLEQTDAQIQGLKAELKSTSSLNSRIEVVNGQMKDASRELQTLRRDLSDVSALKSNVQMLQSNLQRAKTEMQTLKADLQATKALTAKIQGEQNRLGALQEAVAAQKQEQKTQNQVLQLIAQNWKYFNGNFYYFSRDKKPWREAEKFCTSQGAHLASVTSQEEQAFLVQTTSSGDHWIGLTDQGTEGIWRWVDGTPFNNAQSKGFWGKNQPDNWRHRNGEREDCVHVRQQWNDMACGSSYPWVCKKSTGWSAARVG", "length": 548 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-090313-154", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-154#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6EIG7-1", "protein_name": "C-type lectin domain family 6 member A", "gene_name": "CLEC6A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMQEQQPQSTEKRGWLSLRLWSVAGISIALLSACFIVSCVVTYHFTYGETGKRLSELHSYHSSLTCFSEGTKVPAWGCCPASWKSFGSSCYFISSEEKVWSKSEQNCVEMGAHLVVFNTEAEQNFIVQQLNESFSYFLGLSDPQGNNNWQWIDKTPYEKNVRFWHLGEPNHSAEQCASIVFWKPTGWGWNDVICETRRNSICEMNKIYL", "length": 209 }, "evidence": [ { "id": "HGNC:14556", "url": "https://alliancegenome.org/gene/HGNC:14556#orthology", "database": "AGR" }, { "id": "FB:FBgn0040102", "url": "https://alliancegenome.org/gene/FB:FBgn0040102#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6UXB4-1", "protein_name": "C-type lectin domain family 4 member G", "gene_name": "CLEC4G", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDTTRYSKWGGSSEEVPGGPWGRWVHWSRRPLFLALAVLVTTVLWAVILSILLSKASTERAALLDGHDLLRTNASKQTAALGALKEEVGDCHSCCSGTQAQLQTTRAELGEAQAKLMEQESALRELRERVTQGLAEAGRGREDVRTELFRALEAVRLQNNSCEPCPTSWLSFEGSCYFFSVPKTTWAAAQDHCADASAHLVIVGGLDEQGFLTRNTRGRGYWLGLRAVRHLGKVQGYQWVDGVSLSFSHWNQGEPNDAWGRENCVMMLHTGLWNDAPCDSEKDGWICEKRHNC", "length": 293 }, "evidence": [ { "id": "RGD:1597482", "url": "https://alliancegenome.org/gene/RGD:1597482#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BNX1-1", "protein_name": "C-type lectin domain family 4 member G", "gene_name": "Clec4g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNTGEYNKLGSAIEEVSRGQLGRWECYKQRLFFLVLALLVATVLWALILSTLLSSASSKLRVLLSHQDLLRTNASEQKMTLSSLKDDIGACRNCCSVTKAQLQTTLAEFKDIQAKLMEQESILKELQERVTQDLAKASRDRENIRSELFQALEAVKRQNSSCEQCPPSWLPFQGSCYYFSETQATWDTAQSYCGGQGAHLVIVRGLNEQGFLSQHTRGRGYWLGLRAVRHLNKIQGYRWVDGASLNFSHWNSGEPNDSRGHEDCIMMLHSGLWNDAPCTNERDGWICEKRSSCY", "length": 294 }, "evidence": [ { "id": "RGD:1597482", "url": "https://alliancegenome.org/gene/RGD:1597482#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CJ91-1", "protein_name": "CD209 antigen-like protein B", "gene_name": "Cd209b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDSTEAKMQPLSSMDDDELMVSGSRYSIKSSRLRPNSGIKCLAGCSGHSQVPLVLQLLSFLFLAGLLLIILFQVSKTPNTERQKEQEKILQELTQLTDELTSRIPISQGKNESMQAKITEQLMQLKTELLSRIPIFQGQNESIQEKISEQLMQLKAELLSKISSFPVKDDSKQEKIYQQLVQMKTELFRLCRLCPWDWTFLLGNCYFFSKSQRNWNDAVTACKEVKAQLVIINSDEEQTFLQQTSKAKGPTWMGLSDLKKEATWLWVDGSTLSSRFQKYWNRGEPNNIGEEDCVEFAGDGWNDSKCELKKFWICKKSATPCTEG", "length": 325 }, "evidence": [ { "id": "MGI:1916415", "url": "https://alliancegenome.org/gene/MGI:1916415#orthology", "database": "AGR" }, { "id": "HGNC:13523", "url": "https://alliancegenome.org/gene/HGNC:13523#orthology", "database": "AGR" }, { "id": "RGD:1561466", "url": "https://alliancegenome.org/gene/RGD:1561466#orthology", "database": "AGR" }, { "id": "FB:FBgn0040102", "url": "https://alliancegenome.org/gene/FB:FBgn0040102#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IRH8-1", "protein_name": "Triforce, isoform B", "gene_name": "tfc", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MIRPTLIVVLISLASVDSGHNSPVTTIPVAEPISQVPHGFQLGQNNHISSSSNISRSGGGNGRDKRGAQLDPSEIARQNQITQQIFANYLERRLFPNRTANQKIPTIADILPKPKPSPRPRPRGFAASDGGNFKRSGGGAQRNRLAAAASKRQSGYNRKRLREEQEEEEEADDQERDQQPLANQEDFDYDVQESLQSVESEQHDQYYGNIFHRDPSENEVDNDCPNCVDESQYTPNKWTMPLLKLGEKRYYLGIFFKANWFKATQYCRYHGMHLASISSQEENDRLEKHIRDFGLGHEHFWISGTDLADEGNFFWMATGRPITFTNWNAGEPNNFRYENGEEENCLELWNRDGKGLKWNDSPCSFETYFVCEVQPN", "length": 376 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-090313-154", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-154#orthology", "database": "AGR" }, { "id": "MGI:1916415", "url": "https://alliancegenome.org/gene/MGI:1916415#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8N1N0-1", "protein_name": "C-type lectin domain family 4 member F", "gene_name": "CLEC4F", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDGEAVRFCTDNQCVSLHPQEVDSVAMAPAAPKIPRLVQATPAFMAVTLVFSLVTLFVVVQQQTRPVPKPVQAVILGDNITGHLPFEPNNHHHFGREAEMRELIQTFKGHMENSSAWVVEIQMLKCRVDNVNSQLQVLGDHLGNTNADIQMVKGVLKDATTLSLQTQMLRSSLEGTNAEIQRLKEDLEKADALTFQTLNFLKSSLENTSIELHVLSRGLENANSEIQMLNASLETANTQAQLANSSLKNANAEIYVLRGHLDSVNDLRTQNQVLRNSLEGANAEIQGLKENLQNTNALNSQTQAFIKSSFDNTSAEIQFLRGHLERAGDEIHVLKRDLKMVTAQTQKANGRLDQTDTQIQVFKSEMENVNTLNAQIQVLNGHMKNASREIQTLKQGMKNASALTSQTQMLDSNLQKASAEIQRLRGDLENTKALTMEIQQEQSRLKTLHVVITSQEQLQRTQSQLLQMVLQGWKFNGGSLYYFSSVKKSWHEAEQFCVSQGAHLASVASKEEQAFLVEFTSKVYYWIGLTDRGTEGSWRWTDGTPFNAAQNKAPGSKGSCPLRKYIIVNSGMGACSFIDTPPCPWILSN", "length": 589 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-090313-154", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-154#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q91ZW8-1", "protein_name": "CD209 antigen-like protein D", "gene_name": "Cd209d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDSMESKTQQVVIPEDEECLMSGTRYSDISSRLQTKFGIKSLAEYTKQSRNPLVLQLLSFLFLAGLLLIILILVSKVPSSEVQNKIYQELMQLKAEVHDGLCQPCARDWTFFNGSCYFFSKSQRNWHNSTTACQELGAQLVIIETDEEQTFLQQTSKARGPTWMGLSDMHNEATWHWVDGSPLSPSFTRYWNRGEPNNVGDEDCAEFSGDGWNDLSCDKLLFWICKKVSTSSCTTK", "length": 237 }, "evidence": [ { "id": "HGNC:13523", "url": "https://alliancegenome.org/gene/HGNC:13523#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H2X3-1", "protein_name": "C-type lectin domain family 4 member M", "gene_name": "CLEC4M", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSDSKEPRVQQLGLLEEDPTTSGIRLFPRDFQFQQIHGHKSSTGCLGHGALVLQLLSFMLLAGVLVAILVQVSKVPSSLSQEQSEQDAIYQNLTQLKAAVGELSEKSKLQEIYQELTQLKAAVGELPEKSKLQEIYQELTRLKAAVGELPEKSKLQEIYQELTRLKAAVGELPEKSKLQEIYQELTRLKAAVGELPEKSKLQEIYQELTELKAAVGELPEKSKLQEIYQELTQLKAAVGELPDQSKQQQIYQELTDLKTAFERLCRHCPKDWTFFQGNCYFMSNSQRNWHDSVTACQEVRAQLVVIKTAEEQNFLQLQTSRSNRFSWMGLSDLNQEGTWQWVDGSPLSPSFQRYWNSGEPNNSGNEDCAEFSGSGWNDNRCDVDNYWICKKPAACFRDE", "length": 399 }, "evidence": [ { "id": "MGI:1916415", "url": "https://alliancegenome.org/gene/MGI:1916415#orthology", "database": "AGR" }, { "id": "HGNC:13523", "url": "https://alliancegenome.org/gene/HGNC:13523#orthology", "database": "AGR" }, { "id": "RGD:1561466", "url": "https://alliancegenome.org/gene/RGD:1561466#orthology", "database": "AGR" }, { "id": "FB:FBgn0040102", "url": "https://alliancegenome.org/gene/FB:FBgn0040102#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JKF4-1", "protein_name": "C-type lectin domain family 6 member A", "gene_name": "Clec6a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVQERQSQGKGVCWTLRLWSAAVISMLLLSTCFIASCVVTYQFIMDQPSRRLYELHTYHSSLTCFSEGTMVSEKMWGCCPNHWKSFGSSCYLISTKENFWSTSEQNCVQMGAHLVVINTEAEQNFITQQLNESLSYFLGLSDPQGNGKWQWIDDTPFSQNVRFWHPHEPNLPEERCVSIVYWNPSKWGWNDVFCDSKHNSICEMKKIYL", "length": 209 }, "evidence": [ { "id": "HGNC:14556", "url": "https://alliancegenome.org/gene/HGNC:14556#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NNX6-1", "protein_name": "CD209 antigen", "gene_name": "CD209", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSDSKEPRLQQLGLLEEEQLRGLGFRQTRGYKSLAGCLGHGPLVLQLLSFTLLAGLLVQVSKVPSSISQEQSRQDAIYQNLTQLKAAVGELSEKSKLQEIYQELTQLKAAVGELPEKSKLQEIYQELTRLKAAVGELPEKSKLQEIYQELTWLKAAVGELPEKSKMQEIYQELTRLKAAVGELPEKSKQQEIYQELTRLKAAVGELPEKSKQQEIYQELTRLKAAVGELPEKSKQQEIYQELTQLKAAVERLCHPCPWEWTFFQGNCYFMSNSQRNWHDSITACKEVGAQLVVIKSAEEQNFLQLQSSRSNRFTWMGLSDLNQEGTWQWVDGSPLLPSFKQYWNRGEPNNVGEEDCAEFSGNGWNDDKCNLAKFWICKKSAASCSRDEEQFLSPAPATPNPPPA", "length": 404 }, "evidence": [ { "id": "MGI:1916415", "url": "https://alliancegenome.org/gene/MGI:1916415#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9UJ71-1", "protein_name": "C-type lectin domain family 4 member K", "gene_name": "CD207", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTVEKEAPDAHFTVDKQNISLWPREPPPKSGPSLVPGKTPTVRAALICLTLVLVASVLLQAVLYPRFMGTISDVKTNVQLLKGRVDNISTLDSEIKKNSDGMEAAGVQIQMVNESLGYVRSQFLKLKTSVEKANAQIQILTRSWEEVSTLNAQIPELKSDLEKASALNTKIRALQGSLENMSKLLKRQNDILQVVSQGWKYFKGNFYYFSLIPKTWYSAEQFCVSRNSHLTSVTSESEQEFLYKTAGGLIYWIGLTKAGMEGDWSWVDDTPFNKVQSVRFWIPGEPNNAGNNEHCGNIKAPSLQAWNDAPCDKTFLFICKRPYVPSEP", "length": 328 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-090313-154", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-154#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VIX1-1", "protein_name": "Galactose-specific C-type lectin, isoform A", "gene_name": "Lectin-galC1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLKLTVLLITLLVIAKTGWTREKFSIQVNEGNTFGALVKAEPFTKINDGYYFFGTESLNWYEAYEKCRELNSELVTFETDQEFDAVTAFLTANGSRLTYWTSGNDLAKTGSHRWFTNAQRISSLRWARNQPDNAGQKEHCIHLGYIYKDSRKFELNDRPCSQDPNSLFKYICEAPEMETISIVVWK", "length": 186 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-090313-154", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-154#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VLM0-1", "protein_name": "Lectin-29Ca", "gene_name": "lectin-29Ca", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MYKYATCIFSIFALWNFWGVSAKKQDTSTGTNELPKAPMPYYTIENIDMHQQHWFTYNSLRQNGTLWRIGNMEQRLEMRLQSFQNQMETKLRALKQQIEPYMENVKMSNKIKMSVFKKIGSRHFYLEKQKKMPWDSAYDTCRQMGGHLANILDEKELNEIFSEETKKKYWVDINSRANDGASWISTLSGRDVPFLKWKPNLATNIHNHCVYINSNEMYFENCANDNYFACQAEQWA", "length": 236 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-090313-154", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-154#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VM16-1", "protein_name": "C-type lectin domain-containing protein", "gene_name": "Dmel\\CG15818", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFSSTRIILCAFLLLYPYGSLIEAQEGRRYVCLLSDPPNQCSEYCVSALQPVIDHLSKEQQDWGACEVKLNGSVAKLDKIEDQLTATQIQIEAQQAFLVNNISKAIKTEDLEQKLKDIEGNQTALSNQLKDGQKRTENQLTAIQKTLSDIERKLVLQRYQQIGSRYFYIEHNLQVNWRTAEQRCIEMGGHLAAFQNAEEYNAIVGQLNKANYWLGVNDLAKQGEFISLASGKRATYFKWRKNEPKYNNPTQHCAYVFGHENIMIVLSCTTDVMHFICQSDSDV", "length": 283 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-090313-154", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-154#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-285", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-285#orthology", "database": "AGR" }, { "id": "RGD:1597482", "url": "https://alliancegenome.org/gene/RGD:1597482#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VPS1-1", "protein_name": "Lectin-21Cb", "gene_name": "lectin-21Cb", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFKYDTYFLYLIVLLDPQGAQENNCPKVSLSERLEKRGEFSLVEFDPLLKFIVKNPHKELLGEIEGLVGHTENKLQPMKSVIPNQSKALLNYLDLHSKLEYLDAALQKAINSLQCSLKNTKVMSTGKPHPEFQKLGSRYFYIERHVRQNWFDAADKCRRMGGHLATPQDEDELYLIRKQLEARWFWLDISNLVDKDQYISLATGKEVSYLKWRHGEPKKSSTANCAYLYAGDYYTYQCSDRNFFICQAV", "length": 249 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-090313-154", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-154#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VPS2-1", "protein_name": "Lectin-21Ca", "gene_name": "lectin-21Ca", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFQHANFFLHVFMACGLYGIRAKDVCPRMSTDKEVCLVELAPVLKYISNNHKSHWNSANEVQVNETRKQLAKIEGQEKETNDKIKVIHDNVDNEFNALSAKIKNVKNIQRHLASLELQLQETKKALNLSVEAKKVMPKTEIPSQFQKIGWRHFFIEKKHKVDWFKATSMCHKMGAHLLTIQSEDELDAIRTELKDINDGSHDFWLDINDIAKWGEFISLATGMNPPFLKWHKHRPQVQIHQRCVHLRGGEMMDGKCSEQFLFICQLAVN", "length": 269 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-090313-154", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-154#orthology", "database": "AGR" }, { "id": "HGNC:14556", "url": "https://alliancegenome.org/gene/HGNC:14556#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VQ53-1", "protein_name": "C-type lectin domain-containing protein", "gene_name": "mdcds_4396", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MQKLSIWLLLALFAWNAHAPSAAMPSVCLLQDAPQQCGEFCLTALSPMLDHIARHEGEWTSSVLQANATEARLARIETLQTAMNIRQKVLQEGFPKDIVARLDRLESQQAALLRILSKFDRKIVAPKFELIGSRFFYIEDETRRNWTSAGSACRQMGTQLATIRSAEELAALRAKLNKERHYWLDITDLEKEGDFRISASGKRPNFLKWRAGQPNNFSGNQHCVDLLDGLMYDNKCESLSYFICQSDDDSLD", "length": 252 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-285", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-285#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VQU4-1", "protein_name": "Lectin-24A", "gene_name": "lectin-24A", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFRLSVLVLNLLLVSHEFSAGTAKIEIQPLPALCNGYCFPTLKPVMEYVAIHQDKWNTCTEILANEARKDQIQLNIQLDALKADVSNIKASQLSKDEKLDRMEREQFAMHESLETINRYLTVKLDRTKLQLEAIKNTMDYMKAQMDGYFSAINGVQCLQPGFEKIGDRYFYIEEDVELNWLDAQAKCRRMGGHLASIKTKQEFDAIVEKLDDSKSYFLGVNENTKTGDFVSAASGKSCLYHEWGPGEPHHNNDQERCVSILRKLMHVGNCTYEKRFICQYGI", "length": 282 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-090313-154", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-154#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-285", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-285#orthology", "database": "AGR" }, { "id": "RGD:1597482", "url": "https://alliancegenome.org/gene/RGD:1597482#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q9VQX3", "url": "https://www.uniprot.org/uniprotkb/Q9VQX3" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "Q9VQX3", "url": "https://www.uniprot.org/uniprotkb/Q9VQX3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "Q9VQX3", "url": "https://www.uniprot.org/uniprotkb/Q9VQX3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "Q9VQX3", "url": "https://www.uniprot.org/uniprotkb/Q9VQX3" } ], "pmid": "" }, { "name": "D-mannose binding", "id": "GO:0005537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005537", "evidence": [ { "database": "UniProtKB", "id": "Q9VQX3", "url": "https://www.uniprot.org/uniprotkb/Q9VQX3" } ], "pmid": "" }, { "name": "fucose binding", "id": "GO:0042806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042806", "evidence": [ { "database": "UniProtKB", "id": "Q9VQX3", "url": "https://www.uniprot.org/uniprotkb/Q9VQX3" } ], "pmid": "" }, { "name": "pattern recognition receptor activity", "id": "GO:0038187", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038187", "evidence": [ { "database": "UniProtKB", "id": "Q9VQX3", "url": "https://www.uniprot.org/uniprotkb/Q9VQX3" } ], "pmid": "" }, { "name": "glycosylated region protein binding", "id": "GO:0140081", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140081", "evidence": [ { "database": "UniProtKB", "id": "Q9VQX3", "url": "https://www.uniprot.org/uniprotkb/Q9VQX3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 151, "end_pos": 153, "annotation": "n_glycosylation_sequon" }, { "start_pos": 64, "end_pos": 66, "annotation": "n_glycosylation_sequon" }, { "start_pos": 72, "end_pos": 74, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VQX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQX3" }, { "id": "PS50041", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50041" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C-type lectin", "eco_id": "ECO_0000259", "start_pos": 241, "end_pos": 354, "start_aa": "Ile", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 151, "end_pos": 153 }, { "start_pos": 64, "end_pos": 66 }, { "start_pos": 72, "end_pos": 74 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VR05-1", "uniprot_ac": "Q9VR05", "uniprot_id": "PARIS_DROME", "mass": { "chemical_mass": 40502.0, "monoisotopic_mass": 40502.0 }, "refseq": { "ac": "NP_608840", "name": "parkin interacting substrate", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608840" }, "gene_names": [ { "name": "Paris", "type": "recommended", "evidence": [ { "id": "Q9VR05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VR05" } ] }, { "name": "CG15436", "type": "synonym", "evidence": [ { "id": "NP_608840", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608840" }, { "id": "Q9VR05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VR05" } ] }, { "name": "Dmel\\CG15436", "type": "synonym", "evidence": [ { "id": "NP_608840", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608840" } ] }, { "name": "Paris", "type": "synonym", "evidence": [ { "id": "NP_608840", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608840" } ] }, { "name": "dPARIS", "type": "synonym", "evidence": [ { "id": "NP_608840", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608840" } ] } ], "protein_names": [ { "name": "Zinc finger protein Paris", "type": "recommended", "evidence": [ { "id": "Q9VR05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VR05/entry#names_and_taxonomy" } ] }, { "name": "CG15436-PA", "type": "synonym", "evidence": [ { "id": "NP_608840", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608840" } ] }, { "name": "Paris-PA", "type": "synonym", "evidence": [ { "id": "NP_608840", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608840" } ] }, { "name": "Parkin-interacting substrate", "type": "synonym", "evidence": [ { "id": "Q9VR05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VR05/entry#names_and_taxonomy" } ] }, { "name": "parkin interacting substrate", "type": "synonym", "evidence": [ { "id": "NP_608840", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608840" } ] } ], "function": [ { "annotation": "Transcription repressor that inhibits transcription of srl/PGC-1-alpha to negatively regulate mitochondrial biogenesis and thereby promotes neurodegeneration (PubMed:27819722, PubMed:32138754). In neurons, functions downstream of the Pink1-park pathway and is likely to act as part of the Pink1-park homeostatic mechanism that maintains mitochondrial quality and function through degradation (mitophagy) and synthesis (biogenesis) (PubMed:32138754).", "evidence": [ { "database": "UniProtKB", "id": "Q9VR05", "url": "https://www.uniprot.org/uniprotkb/Q9VR05#function" }, { "database": "PubMed", "id": "32138754", "url": "https://glygen.org/publication/PubMed/32138754" }, { "database": "PubMed", "id": "27819722", "url": "https://glygen.org/publication/PubMed/27819722" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VR05", "url": "https://www.uniprot.org/uniprotkb/Q9VR05" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Paris", "url": "https://www.uniprot.org/uniprotkb/Q9VR05", "locus": { "chromosome": "2L", "start_pos": 4465075, "end_pos": 4463611, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0031610", "url": "https://www.ensemblgenomes.org/id/FBgn0031610" } ] } } ], "crossref": [ { "id": "FB:FBgn0031610", "url": "https://alliancegenome.org/gene/FB:FBgn0031610", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "Q9VR05", "url": "https://alphafold.ebi.ac.uk/entry/Q9VR05", "database": "AlphaFoldDB", "categories": [] }, { "id": "FBgn0031610", "url": "https://bgee.org/?page=gene&gene_id=FBgn0031610", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0031610", "url": "https://flybase.org/reports/FBgn0031610", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "33657", "url": "https://www.ncbi.nlm.nih.gov/gene/33657", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VR05", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VR05*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR012934", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012934", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG15436", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG15436", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CTRYFIE", "url": "https://omabrowser.org/oma/group/CTRYFIE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VR05", "url": "https://www.orthodb.org/?gene=Q9VR05", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24408", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24408", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24408:SF58", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24408:SF58", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07776", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07776", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q9VR05", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q9VR05", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_608840", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608840", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VR05", "url": "https://www.uniprot.org/uniprotkb/Q9VR05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VR05-1", "url": "https://www.uniprot.org/uniprotkb/Q9VR05-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEICRVCMDISGKLVNIFDARRRTRVSIAEMIAQCTGFEVKRGDLFSEMICPQCYEDVKSAYGIRQTCEESHQFYCRVRDEGIEDALCALLEEEDWEISEDEDARIDSASAADDDGKSDSKKVAFECRECHKKYQRKGTFLRHMRTHMDGQSFPCPYCKRNFRLRVTLKAHMKTHNAAKPYECSHCAKTFAQQSTLQSHERTHTGERPFKCSQCSKTFIKSSDLRRHIRTHGSERPFKCSKCTKTFTRKFHLDNHFRSHTGERPFKCSHCPKAFAMKQHLKQHSRLHLPDRPFRCSHCPKTFRLSSTLKEHKLVHNAERTFKCPHCASFYKQRKTLARHILEIHK", "length": 346, "header": "sp|Q9VR05-1|PARIS_DROME Isoform 1 of Zinc finger protein Paris OS=Drosophila melanogaster OX=7227 GN=Paris PE=1 SV=2 CANONICAL=Q9VR05-1" }, "isoforms": [ { "isoform_ac": "Q9VR05-1", "url": "https://www.uniprot.org/uniprotkb/Q9VR05/entry#Q9VR05-1", "sequence": { "sequence": "MAEICRVCMDISGKLVNIFDARRRTRVSIAEMIAQCTGFEVKRGDLFSEMICPQCYEDVKSAYGIRQTCEESHQFYCRVRDEGIEDALCALLEEEDWEISEDEDARIDSASAADDDGKSDSKKVAFECRECHKKYQRKGTFLRHMRTHMDGQSFPCPYCKRNFRLRVTLKAHMKTHNAAKPYECSHCAKTFAQQSTLQSHERTHTGERPFKCSQCSKTFIKSSDLRRHIRTHGSERPFKCSKCTKTFTRKFHLDNHFRSHTGERPFKCSHCPKAFAMKQHLKQHSRLHLPDRPFRCSHCPKTFRLSSTLKEHKLVHNAERTFKCPHCASFYKQRKTLARHILEIHK", "length": 346, "header": "sp|Q9VR05-1|PARIS_DROME Isoform 1 of Zinc finger protein Paris OS=Drosophila melanogaster OX=7227 GN=Paris PE=1 SV=2 CANONICAL=Q9VR05-1" }, "locus": { "chromosome": "2L", "start_pos": 4463611, "end_pos": 4465075, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0077442", "url": "https://www.ensemblgenomes.org/id/FBtr0077442" }, { "database": "Ensembl Peptide", "id": "FBpp0077132", "url": "https://www.ensemblgenomes.org/id/FBpp0077132" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VR05", "url": "https://www.uniprot.org/uniprotkb/Q9VR05" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "A Drosophila full-length cDNA resource.", "journal": "Genome Biol.", "date": "2002", "authors": "Stapleton M, Carlson J, Brokstein P, Yu C, Champe M, George R, Guarin H, Kronmiller B, Pacleb J, Park S, Wan K, Rubin GM, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VR05", "url": "https://www.uniprot.org/uniprotkb/Q9VR05" } ], "reference": [ { "type": "PubMed", "id": "12537569", "url": "https://glygen.org/publication/PubMed/12537569" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VR05", "url": "https://www.uniprot.org/uniprotkb/Q9VR05" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "Identifying potential PARIS homologs in D. melanogaster.", "journal": "Genetics and molecular research : GMR", "date": "2016-11-03", "authors": "Merzetti E M, Staveley B E", "evidence": [ { "database": "UniProtKB", "id": "Q9VR05", "url": "https://www.uniprot.org/uniprotkb/Q9VR05" } ], "reference": [ { "type": "PubMed", "id": "27819722", "url": "https://glygen.org/publication/PubMed/27819722" } ] }, { "title": "PARIS induced 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"count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VR20-1", "uniprot_ac": "Q9VR20", "uniprot_id": "OTUD_DROME", "mass": { "chemical_mass": 57417.0, "monoisotopic_mass": 57417.0 }, "refseq": { "ac": "NP_608851", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608851" }, "gene_names": [ { "name": "CG3251", "type": "synonym", "evidence": [ { "id": "NP_608851", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608851" }, { "id": "Q9VR20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VR20" } ] }, { "name": "Dmel\\CG3251", "type": "synonym", "evidence": [ { "id": "NP_608851", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608851" } ] } ], "protein_names": [ { "name": "OTU domain-containing protein CG3251", "type": "recommended", "evidence": [ { "id": "Q9VR20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VR20/entry#names_and_taxonomy" } ] }, { "name": "CG3251-PA", "type": "synonym", "evidence": [ { "id": "NP_608851", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608851" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_608851", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608851" } ] } ], "function": [ { "annotation": "Putative OTU-type deubiquitinase (PubMed:26588485). Catalytically inactive towards all diubiquitin molecules and long K48- and K63- linked ubiquitin chains in vitro (PubMed:26588485). Potential modulator of apoptosis (PubMed:26588485).", "evidence": [ { "database": "UniProtKB", "id": "Q9VR20", "url": "https://www.uniprot.org/uniprotkb/Q9VR20#function" }, { "database": "PubMed", "id": "26588485", "url": "https://glygen.org/publication/PubMed/26588485" } ] } ], "disease": [], "snv": [], "mutagenesis": [ { "start_pos": 40, "end_pos": 40, "sequence_org": "S", "sequence_mut": "C", "comment": "Does not rescue in vitro deubiquitinase activity.", "evidence": [ { "database": "UniProtKB", "id": "Q9VR20", "url": "https://www.uniprot.org/uniprotkb/Q9VR20" }, { "database": "PubMed", "id": "26588485", "url": "https://glygen.org/publication/PubMed/26588485" } ] } ], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VR20", "url": "https://www.uniprot.org/uniprotkb/Q9VR20" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/Q9VR20", "locus": {} } ], "crossref": [ { "id": "FB:FBgn0031622", "url": "https://alliancegenome.org/gene/FB:FBgn0031622", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "Q9VR20", "url": "https://alphafold.ebi.ac.uk/entry/Q9VR20", "database": "AlphaFoldDB", "categories": [] }, { "id": "FBgn0031622", "url": "https://bgee.org/?page=gene&gene_id=FBgn0031622", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd20380", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20380", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22753", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22753", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0031622", "url": "https://flybase.org/reports/FBgn0031622", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "33671", "url": "https://www.ncbi.nlm.nih.gov/gene/33671", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VR20", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VR20*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR003323", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003323", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049769", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049769", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050704", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050704", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG3251", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3251", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CQAVAFK", "url": "https://omabrowser.org/oma/group/CQAVAFK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VR20", "url": "https://www.orthodb.org/?gene=Q9VR20", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12419", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12419", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12419:SF115", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12419:SF115", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02338", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02338", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q9VR20", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q9VR20", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_608851", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608851", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VR20", "url": "https://www.uniprot.org/uniprotkb/Q9VR20", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VR20-1", "url": "https://www.uniprot.org/uniprotkb/Q9VR20-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSEVLQRLASTEVRKARDPIDRFLERRQLFRKHMLGDASSLFRVVAEQVYDTQMLHYEVRMECVRYMFTKWKTFRRFVSGDFDEYLWHLGKTKTAGTILELGAMCHLYRRNVIIYEPFDMGRMVTYNKDYKEILRIFMNSMGHFETVLTMQDVDMAAVCQSVSFKMLYKHLFRLPDVDLAVEWMLYPDTFKMGTEYEFDSRGRAIRLLCRNGRSFKLDRPESTICLLENSQMCPFHNRRLAMGGQFADFSCMRILLEENNIPFSYLVAKSMDPCRYRNVELTSAIEARREAYEFGIYIGDYNFKVGAKCQVQLDTNRRDLLSACYIQSIDKKKSVCKVFIEEQGKLVDVPSDNLHPLPPDEFKAWDFARKRPQRLHNSQMGRQSVQGDQQGFVPDPMPGTAPSMPPPPVADPRPVNVTAQQPPVFGPSRWMEPTRPLMPNPLMIHQTGSFVFVQQPRVGPPSVMMHVLIIVHNAPYMLAFDHAPHPPAPQCTAPF", "length": 495, "header": "sp|Q9VR20-1|OTUD_DROME Isoform 1 of OTU domain-containing protein CG3251 OS=Drosophila melanogaster OX=7227 GN= PE=1 SV=1 CANONICAL=Q9VR20-1" }, "isoforms": [ { "isoform_ac": "Q9VR20-1", "url": "https://www.uniprot.org/uniprotkb/Q9VR20/entry#Q9VR20-1", "sequence": { "sequence": "MSEVLQRLASTEVRKARDPIDRFLERRQLFRKHMLGDASSLFRVVAEQVYDTQMLHYEVRMECVRYMFTKWKTFRRFVSGDFDEYLWHLGKTKTAGTILELGAMCHLYRRNVIIYEPFDMGRMVTYNKDYKEILRIFMNSMGHFETVLTMQDVDMAAVCQSVSFKMLYKHLFRLPDVDLAVEWMLYPDTFKMGTEYEFDSRGRAIRLLCRNGRSFKLDRPESTICLLENSQMCPFHNRRLAMGGQFADFSCMRILLEENNIPFSYLVAKSMDPCRYRNVELTSAIEARREAYEFGIYIGDYNFKVGAKCQVQLDTNRRDLLSACYIQSIDKKKSVCKVFIEEQGKLVDVPSDNLHPLPPDEFKAWDFARKRPQRLHNSQMGRQSVQGDQQGFVPDPMPGTAPSMPPPPVADPRPVNVTAQQPPVFGPSRWMEPTRPLMPNPLMIHQTGSFVFVQQPRVGPPSVMMHVLIIVHNAPYMLAFDHAPHPPAPQCTAPF", "length": 495, "header": "sp|Q9VR20-1|OTUD_DROME Isoform 1 of OTU domain-containing protein CG3251 OS=Drosophila melanogaster OX=7227 GN= PE=1 SV=1 CANONICAL=Q9VR20-1" }, "locus": { "chromosome": "2L", "start_pos": 4688965, "end_pos": 4690702, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0077422", "url": "https://www.ensemblgenomes.org/id/FBtr0077422" }, { "database": "Ensembl Peptide", "id": "FBpp0077113", "url": "https://www.ensemblgenomes.org/id/FBpp0077113" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VR20", "url": "https://www.uniprot.org/uniprotkb/Q9VR20" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VR20", "url": "https://www.uniprot.org/uniprotkb/Q9VR20" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "Evolutionary Loss of Activity in De-Ubiquitylating Enzymes of the OTU Family.", "journal": "PloS one", "date": "2015", "authors": "Louis M, Hofmann K, Broemer M", "evidence": [ { "database": "UniProtKB", "id": "Q9VR20", "url": "https://www.uniprot.org/uniprotkb/Q9VR20" } ], "reference": [ { "type": "PubMed", "id": "26588485", "url": "https://glygen.org/publication/PubMed/26588485" } ] } ], "pathway": [ { "id": "dme:Dmel_CG3251", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3251", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1P7L2-1", "protein_name": "OTU domain-containing protein 4", "gene_name": "otud4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MELRAASADAQQQLAGDRTHESRMDEYLRSLGFYRKKIAKDGSCLFRAVAEQILHCQGLHTQVRAACVNYLRQNRPTYELFIEGNFEKYLENLQDPQSWVGQVEISALAELYKHDFIIFQEPDQPPVNLTENGFTHKVRLCFLNGNHYDSVYPESFEKNAAVCQSILYELLYERVCGVERNVVGSCVKGGRGRDRQDSEECKSSEESELEEDDFWSTEPREKTSNGMNARPPQRGRGRGYSRGRGREFLSTKVQKSLNPTLYRNVEYDVWLRSKRLQQQRDFCIAAGMQYSVGDKCKVQLSGSNRLYSAYVKEVSPDNGPVTVFIEELNKQQTVPLLNLRLPSEEPQSWHTVSERGKRQAAPNNEWESRGGRRPNRMQSQSAPSVRVHKQHSWPPQATTDDARNKFSRRSDQRSSPVCILPEEEEESVVLELLHKDEHNFPSLGPSPQTATPGEVIKKGGEKKSHRKKEQKENFMETEASQKPLQRQKSGTEEKHGIKFSEEPRQRSSSTINEKLQEKPIPVAASPPSPAIFLSGPKTPISSSNSATSPDPNRSAPEAVKKATIQPKSSPAQNPDNSHLEPVSTLASLQHISRVAPVSETTPASQFISGAAPVSVVPPASQSISATTPAPQSISAAAPVSVSTPASDSILVAAPDSATTPASQYIPGSRAVSVSTPAPQSISGATAVSSNTPTPHSISRATAVSVTAPAPHFTFVATAESISTPSPHSISGATAVATPAPIQSAPALNSTKPSFQMAQLPTVELLPRTEAPSQFTSVELVASQITLVPLPTSTPTQTTLAPTCPIPAAPVESSLCIQTLPPANTSTLSPTPSSTIPISAQAQVATPVLDSPGLSSTPHPIHANNAPPIPKKTVDPQTTMMPVPLPHAAPTSISPSIGSANASPPDLPLVSPKESVPSACETSTIPASGAAPVVDHPSQPQHLPFPQVQWSQLLQDPVYPGFPQNEKGQLEPPPPFSYSQKGEDLPKDISVLKFFFNLGVKAYTQPMFPPIVYLAPLNQAYLRGPSPSSDSPANPTITSWQPENPSSQPQSLSSMVDTPLDSHAPIAPVAAGSSPVDPIEVRGYNDPPSIPMHVPPRPPMPWSAPSVSSAYPGGYPTTPPVQFSTPPYPPPGNQMYPPSSVGYHRMPFPPMPLEAINHGPHGPIDVLPFARPTLERGQENGQLSINPQFRSVQNSAGFPGGQPHFLSGVDFKSVDTPVSLGGMEPPPYGGHCSVPSFQIGPLQGDMSGLIPLPNGSLGRQGGAFPKNLHAEDSSRLVHTFSPEEKWPEEMESTNVDLRVPQLYYSHSYRGGGRRGQEDRGGYRGRSQRGRKDYIGRGRQDDQSYRHYGRRGAGPQLPYQ", "length": 1358 }, "evidence": [ { "id": "HGNC:24949", "url": "https://alliancegenome.org/gene/HGNC:24949#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-5338", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-5338#orthology", "database": "AGR" }, { "id": "MGI:1098801", "url": "https://alliancegenome.org/gene/MGI:1098801#orthology", "database": "AGR" }, { "id": "RGD:1305606", "url": "https://alliancegenome.org/gene/RGD:1305606#orthology", "database": "AGR" }, { "id": "FB:FBgn0031622", "url": "https://alliancegenome.org/gene/FB:FBgn0031622#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABK0LA32-1", "protein_name": "OTU domain-containing protein 4", "gene_name": "Otud4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAAVGAPDGVDQGGAGPLEDATPMDAYLRKLGLYRKLVAKDGSCLFRAVAEQVLHSQSRHVEVRMACIRYLRDNREKFEAFIEGSFEEYLKRLENPQEWVGQVEISALSLMYRKDFVIYQEPNVSPSHVTENNFPEKVLLCFSNGNHYDIVYPITYRDSSAVCQSLLYELLYEKVFKTDVSKIMMGLETSEVADESNSEISDSEDDSCKSKSTAATDVNGFKSSGSENPKNHGNSADLPLSRKVLKSLSPAVYRNVEYEIWLKSKQAQQKRDYSIAAGLQYEGGERCHQVRLDHNGKLSNADIHGVHSENGPVLSEELGKKQTPKNLKPPPPESWNTVSGKKMKKPNSGQNFHSDTDYRGPKNLNKPIKAPSALPPRLQHPPAGVRQHALSSHSTGPQSQKSSSEHKNLSRVPSQITRKPDRERAEDFDHVSRESYYFGLSPEERREKQAIEESRLLYEIQNRDEQAFPALSSSSVSQSPQNSNACVPRKSSHARDRKGSMRRVDAEERKDKDSLRGHTHMDKKPEPSTLEISDDKCTRVSSPSKSKKECPSPVEQKPAEHIPLSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTFGPTGVPAQIPILSVTQTTGPDAAVSQAHLTPSPVPVSIQAVNQPLMPLPQTMSLYQDPLYPGFPCSEKGDRAIAPPYSLCQTGEDLPKDKNILRFFFNLGVKAYSCPMWAPHSYLYPLHQAYMAACRVYPKVPVPVYPQSTWFQEAPPAQSESDCPCADAHYSMHPEASVNGQMPQAEIGPPAFSSPLVIPPSQVSEGHGQLSYQPELESESPGQLLHAEYEESLSGKNMYPQQSFGPNPFLGPVPIAPPFFPHVWYGYPFQGFVENPVMRQNIVLPPDDKGELDLPLENLDLSKECDSVSAVDEFPEARVEGAHSLSEASVSSKHEGRVEQSSQTRKADIDLSSGSSGVEGKAHPPTQILNREREAVSAEPEPKRTIQSLKEKPEKVKDPKTAADVLSSGANSVDRLQRPKEESSEDENEVSNILRSGRSKQFYNQTYGSRKYKSDWGSSGRGGYQHVRGEESWKGQPNRSRDEGYQYHRHVRGRPYRGDRRRSGMGDGHRGQHT", "length": 1106 }, "evidence": [ { "id": "HGNC:24949", "url": "https://alliancegenome.org/gene/HGNC:24949#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-5338", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-5338#orthology", "database": "AGR" }, { "id": "MGI:1098801", "url": "https://alliancegenome.org/gene/MGI:1098801#orthology", "database": "AGR" }, { "id": "RGD:1305606", "url": "https://alliancegenome.org/gene/RGD:1305606#orthology", "database": "AGR" }, { "id": "FB:FBgn0031622", "url": "https://alliancegenome.org/gene/FB:FBgn0031622#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AC58I980-1", "protein_name": "UDP-N-acetylglucosamine transferase subunit ALG13", "gene_name": "alg13", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MQKALKKYFVSMDEYLASIGLYRKMMARDASCLFRAVSEQLYYSQNYHQRIRKECVNFIRANRCNFEPFVEGSFEKYLERLEDPKETVGQVIIKALSLLYRRCFVIYRYPGKPPTEIAEEDNLPKILLCCSNNGHYDIVYPKSYPVDAAVCQALLYELLYTRVLGVEEDEIQAALEGFKGGGRRYRNSHSMCSEDASYDTPEDRSQSDFFREDWESRGHCRFDDRPRVGAEDQKVTEGSGKLALPYKVLKALEPELYRNVEFDVWQDSRKELQKTDYMVFAGRQYFLGDKCQVRLDPKGKYYNAFIQEVGTHSTAVTVFIEELGEKHLVSLTNLKPVNPVPAWNITPSRKGNSYSHAEQYPGELDPELRGRRRFFKKPRGKEMLMAVSFSRPQPGLPPRLQPGPGNIHPVRSPGVHSPAPPPPGLIYEHYRPHPPPRQPRGYGPPRSSARFLNRHHLIGPDMAYYPSPSKRCYQSFDNYSFRSRRSRRQMHTLNKECLSCVPEPGEETQDMEGSITFYELEETDEGAFSPISGQAVSSPMVPGATAYWVPRVPSPIPPSGKQAMTSSEEDPDERSAGGDQGEYSEEYIYSAAEAGYQSPSVYAAAAESTTNLTIQEGSSRAGSPQEGVATYSYSQQVVVKSSVLSSSQPINSAPAAIFTSNSSSSSTGSSQTPPNSLQPNNILTPGQLPPGRPAVPWFVNELGEPVAMAPPPPYSYDPNGSDLPRDCKVLQYYYNLGVQWYQQSYWHSMVHLQQVYPHQAADAQFQSYQSTAPPADHTVPQAYPDSVRMCPHPQGDMPSNGAPLGMENPPTVVPGTVFYPVVQEQCGQPALHSTYDPYMPVLSTTYHYLTPWTPGAAPHSRFHHTTYCPSSSHPPVNYITAPGHPNHLPHSQFV", "length": 894 }, "evidence": [ { "id": "MGI:1914824", "url": "https://alliancegenome.org/gene/MGI:1914824#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "B2RRE7-1", "protein_name": "OTU domain-containing protein 4", "gene_name": "Otud4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEAAVGAPDGVDQGGVGPLEDETPMDAYLRKLGLYRKLVAKDGSCLFRAVAEQVLHSQSRHVEVRMACIRYLRENREKFEAFIEGSFEEYLKRLENPQEWVGQVEISALSLMYRKDFVIYQEPNVSPSHVTENNFPEKVLLCFSNGNHYDIVYPITYKDSSAMCQSLLYELLYEKVFKTDVSKIMMGLEASEVAEESNSEISDSEDDSCKSKSTAATDVNGFKPSGSENPKNNGNSADLPLSRKVLKSLNPAVYRNVEYEIWLKSKQAQQKRDYSIAAGLQYEVGDKCHQVRLDHNGKLSNADIHGVHSENGLVLSEELGKKHTPKNLKPPPPESWNTVSGKKMKKPNSGQNFHSDTDYRGPKNLNKPIKAPSALPPRLQHPSSGVRQHAFSSHSTGSQSQKSSSEHKNLSRMPSQITRKPDRERAEDFDHVSRESYYFGLSPEERREKQAIEESRLLYEIQNRDEQAFPALSSSSVSQSPSQNSNACVPRKSSHARDRKGSMRRADAEERKDKDSLRGHTHVDKKPEPSTLEISDDKCTRVSSPSKSKKECPSPVEQKPAEHIPLSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTFGPTGVPAQIPILSVTQTTGPDAAVSQAHLTPSPVPVSIQAVNQPLMPLPQTMSLYQDPLYPGFPCSEKGDRAIAPPYSLCQTGEDLPKDKNILRFFFNLGVKAYSCPMWAPHSYLYPLHQAYMAACRMYPKVPVPVYPQNTWFQEAPPAQSESDCPCTDAHYSLHPEASVNGQMPQAEMGPPAFASPLVIPPSQVSEGHGQLSYQPELESENPGQLLHAEYEESLSGKNMYPQQSFGPNPFLGPVPIAPPFFPHVWYGYPFQGFVENPVMRQNIVLPPDDKGELDLPLENLDLSKECDSVSAVDEFPDARVEGAHSLSAASVSSKHEGRVEQSSQTRKADIDLASGSSAVEGKGHPPTQILNREREPGSAEPEPKRTIQSLKEKPEKVKDPKTAADVVSPGANSVDRLQRPKEESSEDENEVSNILRSGRSKQFYNQTYGSRKYKSDWGSSGRGGYQHVRGEESWKGQPNRSRDEGYQYHRHVRGRPYRGDRRRSGMGDGHRGQHT", "length": 1107 }, "evidence": [ { "id": "HGNC:24949", "url": "https://alliancegenome.org/gene/HGNC:24949#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-5338", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-5338#orthology", "database": "AGR" }, { "id": "MGI:1098801", "url": "https://alliancegenome.org/gene/MGI:1098801#orthology", "database": "AGR" }, { "id": "RGD:1305606", "url": "https://alliancegenome.org/gene/RGD:1305606#orthology", "database": "AGR" }, { "id": "FB:FBgn0031622", "url": "https://alliancegenome.org/gene/FB:FBgn0031622#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P10383-1", "protein_name": "Deubiquitinase otu", "gene_name": "otu", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDMQVQRPITSGSRQAPDPYDQYLESRGLYRKHTARDASSLFRVIAEQMYDTQMLHYEIRLECVRFMTLKRRIFEKEIPGDFDSYMQDMSKPKTYGTMTELRAMSCLYRRNVILYEPYNMGTSVVFNRRYAENFRVFFNNENHFDSVYDVEYIERAAICQSIAFKLLYQKLFKLPDVSFAVEIMLHPHTFNWDRFNVEFDDKGYMVRIHCTDGRVFKLDLPGDTNCILENYKLCNFHSTNGNQSINARKGGRLEIKNQEERKASGSSGHEPNDLLPMCPNRLESCVRQLLDDGISPFPYKVAKSMDPYMYRNIEFDCWNDMRKEAKLYNVYINDYNFKVGAKCKVELPNETEMYTCHVQNISKDKNYCHVFVERIGKEIVVPYESLHPLPPDEYRPWSLPFRYHRQMPRLPLPKYAGKANKSSKWKKNKLFEMDQYFEHSKCDLMPYMPVDNCYQGVHIQDDEQRDHNDPEQNDQNPTTEQRDREEPQAQKQHQRTKASRVQPQNSSSSQNQEVSGSAAPPPTQYMNYVPMIPSRPGHLPPPWPASPMAIAEEFPFPISGTPHPPPTEGCVYMPFGGYGPPPPGAVALSGPHPFMPLPSPPLNVTGIGEPRRSLHPNGEDLPVDMVTLRYFYNMGVDLHWRMSHHTPPDELGMFGYHQQNNTDQQAGRTVVIGATEDNLTAVESTPPPSPEVANATEQSPLEKSAYAKRNLNSVKVRGKRPEQLQDIKDSLGPAAFLPTPTPSPSSNGSQFSFYTTPSPHHHLITPPRLLQPPPPPPIFYHKAGPPQLGGAAQGQTPYAWGMPAPVVSPYEVINNYNMDPSAQPQQQQPATLQPAPLSVQSQPAAVYAATRHH", "length": 853 }, "evidence": [ { "id": "MGI:1914824", "url": "https://alliancegenome.org/gene/MGI:1914824#orthology", "database": "AGR" }, { "id": "HGNC:24949", "url": "https://alliancegenome.org/gene/HGNC:24949#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-5338", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-5338#orthology", "database": "AGR" }, { "id": "MGI:1098801", "url": "https://alliancegenome.org/gene/MGI:1098801#orthology", "database": "AGR" }, { "id": "RGD:1305606", "url": "https://alliancegenome.org/gene/RGD:1305606#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P53178-1", "protein_name": "UDP-N-acetylglucosamine transferase subunit ALG13", "gene_name": "ALG13", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MGIIEEKALFVTCGATVPFPKLVSCVLSDEFCQELIQYGFVRLIIQFGRNYSSEFEHLVQERGGQRESQKIPIDQFGCGDTARQYVLMNGKLKVIGFDFSTKMQSIIRDYSDLVISHAGTGSILDSLRLNKPLIVCVNDSLMDNHQQQIADKFVELGYVWSCAPTETGLIAGLRASQTEKLKPFPVSHNPSFERLLVETIYS", "length": 202 }, "evidence": [ { "id": "MGI:1914824", "url": "https://alliancegenome.org/gene/MGI:1914824#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q01804-1", "protein_name": "OTU domain-containing protein 4", "gene_name": "OTUD4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEAAVGVPDGGDQGGAGPREDATPMDAYLRKLGLYRKLVAKDGSCLFRAVAEQVLHSQSRHVEVRMACIHYLRENREKFEAFIEGSFEEYLKRLENPQEWVGQVEISALSLMYRKDFIIYREPNVSPSQVTENNFPEKVLLCFSNGNHYDIVYPIKYKESSAMCQSLLYELLYEKVFKTDVSKIVMELDTLEVADEDNSEISDSEDDSCKSKTAAAAADVNGFKPLSGNEQLKNNGNSTSLPLSRKVLKSLNPAVYRNVEYEIWLKSKQAQQKRDYSIAAGLQYEVGDKCQVRLDHNGKFLNADVQGIHSENGPVLVEELGKKHTSKNLKAPPPESWNTVSGKKMKKPSTSGQNFHSDVDYRGPKNPSKPIKAPSALPPRLQHPSGVRQHAFSSHSSGSQSQKFSSEHKNLSRTPSQIIRKPDRERVEDFDHTSRESNYFGLSPEERREKQAIEESRLLYEIQNRDEQAFPALSSSSVNQSASQSSNPCVQRKSSHVGDRKGSRRRMDTEERKDKDSIHGHSQLDKRPEPSTLENITDDKYATVSSPSKSKKLECPSPAEQKPAEHVSLSNPAPLLVSPEVHLTPAVPSLPATVPAWPSEPTTFGPTGVPAPIPVLSVTQTLTTGPDSAVSQAHLTPSPVPVSIQAVNQPLMPLPQTLSLYQDPLYPGFPCNEKGDRAIVPPYSLCQTGEDLPKDKNILRFFFNLGVKAYSCPMWAPHSYLYPLHQAYLAACRMYPKVPVPVYPHNPWFQEAPAAQNESDCTCTDAHFPMQTEASVNGQMPQPEIGPPTFSSPLVIPPSQVSESHGQLSYQADLESETPGQLLHADYEESLSGKNMFPQPSFGPNPFLGPVPIAPPFFPHVWYGYPFQGFIENPVMRQNIVLPSDEKGELDLSLENLDLSKDCGSVSTVDEFPEARGEHVHSLPEASVSSKPDEGRTEQSSQTRKADTALASIPPVAEGKAHPPTQILNRERETVPVELEPKRTIQSLKEKTEKVKDPKTAADVVSPGANSVDSRVQRPKEESSEDENEVSNILRSGRSKQFYNQTYGSRKYKSDWGYSGRGGYQHVRSEESWKGQPSRSRDEGYQYHRNVRGRPFRGDRRRSGMGDGHRGQHT", "length": 1114 }, "evidence": [ { "id": "HGNC:24949", "url": "https://alliancegenome.org/gene/HGNC:24949#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-5338", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-5338#orthology", "database": "AGR" }, { "id": "MGI:1098801", "url": "https://alliancegenome.org/gene/MGI:1098801#orthology", "database": "AGR" }, { "id": "RGD:1305606", "url": "https://alliancegenome.org/gene/RGD:1305606#orthology", "database": "AGR" }, { "id": "FB:FBgn0031622", "url": "https://alliancegenome.org/gene/FB:FBgn0031622#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D8C3-1", "protein_name": "UDP-N-acetylglucosamine transferase subunit ALG13", "gene_name": "Alg13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKRAFVTVGTTSFDELVARVVANDCVQILESLGYNHLVLQVGRGTVVPKPFRTESFTLDVYRYKDSLKEDLQQADLVISHAGAGSCLESLEKGKPLVVVVNEKLMNNHQFELAKQLHKEGHLFYCTCRVLSCPAPVSLLLVLLGSAKILQQLPSATLSCFGYLPTQAPVLVATAYSYLHSVFSSFPPLSTFLIIPCTMQKGWKKYCGQKSLNEASMDEYLGSLGLFRKVVAKDASCLFRAISEQLFHSQIHHLQIRRACVSYMKENQQAFESYVEGSFEKYLERLGDPKESAGQLELKALSLIYNRDFIIYRYPGKPPTQVTDNGFEDKIILCYSNNGHYDSVYSKEFQSTAGICQAILYELLYKDVFVVDEETLKTAVDLFRSGSRRNKHHALTASVEGSSDQKSSTEDRTEEAAACSSAASTPEGNKQGTERQKVPESPSKMLFPYKVLKALDPEIYRNVEFDAWLDSRKELQKSECVEYGGRYYFLGDKCQVCMESGGKYYNAHIQEIDNDKSSVVVFIEEFAERHSIPLAHVRPVNQVALLPSWNAIPIRNGRGYPTITGGYFPEIVMTDMNMKQRKKMFKKFRGKEIYMTMAYSRGDPLVPSRIQHSMHYGHDPLLYYSQTAGHILSSQHFYPQHSSQRQGRGYGMPRDSSHLISKQNLPNPKVGFCSGSGRKCCQSYDNVSYRSRSFRRSHRQMHCMNKGCQYGFAPENGVEETVTFYALEEGNETAYSTLPNNGGPTTMVPATSGYCVARQGYNSCKPPLNSGDSNDHCDNGGYHGDYLYSSEQGYETSSVYTTTVSTANLSLQDSGPSSVPQDTVTSYNYPQKVLENSAAIAVSWASHVPVPVIPNCAGDNEALRTSDISSQNAIQPGFVPPPAQGSPAYLEPSAAGAAGAAAAAAAAAAPVATPVAAPLPLPPPLPPPPPATLEAGDASGFPLPPPPPPPPPPPPPYSYDPSGSDLPQDTKVLQYYFNLGLQCYHHNYWHPMVYMPHVQQQLQPQPQPQPQPQPQPQPQPQPQPQQPQQQQPPPQQQQQQQEQVHGESYPDCTEQPLVDQSAPQVYSDVVREDGTQADVSTNDTFPIADAVPLPHGAVYYPVMTDPYGSPLLGFDSYVPVASDYSSIAMWHPVNAACGASAQIHGAMNPGPIGYMLLPNSPHYTPQN", "length": 1166 }, "evidence": [ { "id": "MGI:1914824", "url": "https://alliancegenome.org/gene/MGI:1914824#orthology", "database": "AGR" }, { "id": "FB:FBgn0031622", "url": "https://alliancegenome.org/gene/FB:FBgn0031622#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NP73-1", "protein_name": "UDP-N-acetylglucosamine transferase subunit ALG13", "gene_name": "ALG13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKCVFVTVGTTSFDDLIACVSAPDSLQKIESLGYNRLILQIGRGTVVPEPFSTESFTLDVYRYKDSLKEDIQKADLVISHAGAGSCLETLEKGKPLVVVINEKLMNNHQLELAKQLHKEGHLFYCTCRVLTCPGQAKSIASAPGKCQDSAALTSTAFSGLDFGLLSGYLHKQALVTATHPTCTLLFPSCHAFFPLPLTPTLYKMHKGWKNYCSQKSLNEASMDEYLGSLGLFRKLTAKDASCLFRAISEQLFCSQVHHLEIRKACVSYMRENQQTFESYVEGSFEKYLERLGDPKESAGQLEIRALSLIYNRDFILYRFPGKPPTYVTDNGYEDKILLCYSSSGHYDSVYSKQFQSSAAVCQAVLYEILYKDVFVVDEEELKTAIKLFRSGSKKNRNNAVTGSEDAHTDYKSSNQNRMEEWGACYNAENIPEGYNKGTEETKSPENPSKMPFPYKVLKALDPEIYRNVEFDVWLDSRKELQKSDYMEYAGRQYYLGDKCQVCLESEGRYYNAHIQEVGNENNSVTVFIEELAEKHVVPLANLKPVTQVMSVPAWNAMPSRKGRGYQKMPGGYVPEIVISEMDIKQQKKMFKKIRGKEVYMTMAYGKGDPLLPPRLQHSMHYGHDPPMHYSQTAGNVMSNEHFHPQHPSPRQGRGYGMPRNSSRFINRHNMPGPKVDFYPGPGKRCCQSYDNFSYRSRSFRRSHRQMSCVNKESQYGFTPGNGQMPRGLEETITFYEVEEGDETAYPTLPNHGGPSTMVPATSGYCVGRRGHSSGKQTLNLEEGNGQSENGRYHEEYLYRAEPDYETSGVYSTTASTANLSLQDRKSCSMSPQDTVTSYNYPQKMMGNIAAVAASCANNVPAPVLSNGAAANQAISTTSVSSQNAIQPLFVSPPTHGRPVIASPSYPCHSAIPHAGASLPPPPPPPPPPPPPPPPPPPPPPPPPPPALDVGETSNLQPPPPLPPPPYSCDPSGSDLPQDTKVLQYYFNLGLQCYYHSYWHSMVYVPQMQQQLHVENYPVYTEPPLVDQTVPQCYSEVRREDGIQAEASANDTFPNADSSSVPHGAVYYPVMSDPYGQPPLPGFDSCLPVVPDYSCVPPWHPVGTAYGGSSQIHGAINPGPIGCIAPSPPASHYVPQGM", "length": 1137 }, "evidence": [ { "id": "MGI:1914824", "url": "https://alliancegenome.org/gene/MGI:1914824#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VAP1-1", "protein_name": "UDP-N-acetylglucosamine transferase subunit ALG13", "gene_name": "Alg13", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MHLNTVYITVGTTKFDALISTASTEPALKALQNRKCTKLVIQHGNSQPLTDDEIQLIRKNYGIQIEQYNFRPNTEDIKSADLIIGHAGAGTCMDILNNQKPGLIVINDTLMDNHQLELAKQLAAENYLYYCKVTDVDAQLATLDFEALKPYETKPENLSKFVSAINQLMSH", "length": 171 }, "evidence": [ { "id": "MGI:1914824", "url": "https://alliancegenome.org/gene/MGI:1914824#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "Q9VR20", "url": "https://www.uniprot.org/uniprotkb/Q9VR20" } ], "pmid": "" }, { "name": "regulation of signal transduction", "id": "GO:0009966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009966", "evidence": [ { "database": "UniProtKB", "id": "Q9VR20", "url": "https://www.uniprot.org/uniprotkb/Q9VR20" } ], "pmid": "" }, { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "Q9VR20", "url": "https://www.uniprot.org/uniprotkb/Q9VR20" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "K63-linked deubiquitinase activity", "id": "GO:0061578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061578", "evidence": [ { "database": "UniProtKB", "id": "Q9VR20", "url": "https://www.uniprot.org/uniprotkb/Q9VR20" } ], "pmid": "" }, { "name": "serine-type peptidase activity", "id": "GO:0008236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008236", "evidence": [ { "database": "UniProtKB", "id": "Q9VR20", "url": "https://www.uniprot.org/uniprotkb/Q9VR20" } ], "pmid": "" }, { "name": "deubiquitinase activity", "id": "GO:0101005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0101005", "evidence": [ { "database": "UniProtKB", "id": "Q9VR20", "url": "https://www.uniprot.org/uniprotkb/Q9VR20" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 416, "end_pos": 418, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q9VR20-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 495, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q9VR20-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q9VR20" } ], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VR20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VR20" }, { "id": "PRU00139", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00139" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "OTU", "eco_id": "ECO_0000255", "start_pos": 29, "end_pos": 150, "start_aa": "Leu", "end_aa": "Met", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q9VR20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VR20" }, { "id": "PRU00211", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00211" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tudor", "eco_id": "ECO_0000255", "start_pos": 302, "end_pos": 364, "start_aa": "Asn", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 416, "end_pos": 418 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VR21", "url": "https://www.uniprot.org/uniprotkb/Q9VR21" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VR21", "url": "https://www.uniprot.org/uniprotkb/Q9VR21" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VR21", "url": "https://www.uniprot.org/uniprotkb/Q9VR21" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VR21", "url": "https://www.uniprot.org/uniprotkb/Q9VR21" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VR21", "url": "https://www.uniprot.org/uniprotkb/Q9VR21" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VR21", "url": "https://www.uniprot.org/uniprotkb/Q9VR21" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VR21", "url": "https://www.uniprot.org/uniprotkb/Q9VR21" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VR21", "url": "https://www.uniprot.org/uniprotkb/Q9VR21" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VR21", "url": "https://www.uniprot.org/uniprotkb/Q9VR21" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, 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"10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VR30", "url": "https://www.uniprot.org/uniprotkb/Q9VR30" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VR30", "url": "https://www.uniprot.org/uniprotkb/Q9VR30" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VR30", "url": "https://www.uniprot.org/uniprotkb/Q9VR30" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VR30", "url": "https://www.uniprot.org/uniprotkb/Q9VR30" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VR30", "url": "https://www.uniprot.org/uniprotkb/Q9VR30" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VR30", "url": "https://www.uniprot.org/uniprotkb/Q9VR30" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VR30", "url": "https://www.uniprot.org/uniprotkb/Q9VR30" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VR30", "url": "https://www.uniprot.org/uniprotkb/Q9VR30" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"id": "Q9VR33-1", "url": "https://www.uniprot.org/uniprotkb/Q9VR33-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAIKNITLGILYGLWDSIRGMTLVLHIDDEVNRQNAEQEHRQQLRRTDKDRYERARRSPSPVPSSAAAMIREEYAKQAEENADERTLEKILGKKPAAQDQHPQGEKKIAKKLFKCCMLNGGFTWLSIVLFENALLPTLKFCLTIFYGAHSETLPVVWGWLHPILSLLFGMMWVLPIFMLSKIVSSLWFADIANAAYRVRKGRPQLIPGISKLVADFLFSMVVQMLFLVQSMLVNLVPVKYVGSSLCFVHLCLLYSLYSFEYKWFNMGWELHRRLTYIEKNWPYFFGFGIPLTVLTNLSSSVIVSSCIFSIFFPLFILSGNEAKPIVDTTEVSLRLFSPVVFISNLCFGGNPWSKANRLSAMQRQQYELQQRQRLLQRDEQLLKQRKQQYVQQQRLQQEQLMRRDRSHSRSQTPQLGHPHRYAQAPVFDAGRVRDSSASSTHSSNAPSINSHRPPPYYGSSLRGAAPLVPTPVPGAPRAPLTPPVIRQESGPDDWNL", "length": 497, "header": "tr|Q9VR33-1|Q9VR33_DROME Isoform 1 of Tank, isoform A OS=Drosophila melanogaster OX=7227 GN=tank PE=3 SV=1 CANONICAL=Q9VR33-1" }, "isoforms": [ { "isoform_ac": "Q9VR33-1", "url": "https://www.uniprot.org/uniprotkb/Q9VR33/entry#Q9VR33-1", "sequence": { "sequence": 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systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VR33", "url": "https://www.uniprot.org/uniprotkb/Q9VR33" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VR33", "url": "https://www.uniprot.org/uniprotkb/Q9VR33" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VR33", "url": "https://www.uniprot.org/uniprotkb/Q9VR33" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VR33", "url": "https://www.uniprot.org/uniprotkb/Q9VR33" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VR33", "url": "https://www.uniprot.org/uniprotkb/Q9VR33" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VR33", "url": "https://www.uniprot.org/uniprotkb/Q9VR33" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VR33", "url": "https://www.uniprot.org/uniprotkb/Q9VR33" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VR33", "url": "https://www.uniprot.org/uniprotkb/Q9VR33" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VR33", "url": "https://www.uniprot.org/uniprotkb/Q9VR33" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG15626", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG15626", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "O14681-1", "protein_name": "Etoposide-induced protein 2.4 homolog", "gene_name": "EI24", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADSVKTFLQDLARGIKDSIWGICTISKLDARIQQKREEQRRRRASSVLAQRRAQSIERKQESEPRIVSRIFQCCAWNGGVFWFSLLLFYRVFIPVLQSVTARIIGDPSLHGDVWSWLEFFLTSIFSALWVLPLFVLSKVVNAIWFQDIADLAFEVSGRKPHPFPSVSKIIADMLFNLLLQALFLIQGMFVSLFPIHLVGQLVSLLHMSLLYSLYCFEYRWFNKGIEMHQRLSNIERNWPYYFGFGLPLAFLTAMQSSYIISGCLFSILFPLFIISANEAKTPGKAYLFQLRLFSLVVFLSNRLFHKTVYLQSALSSSTSAEKFPSPHPSPAKLKATAGH", "length": 340 }, "evidence": [ { "id": "RGD:1309868", "url": "https://alliancegenome.org/gene/RGD:1309868#orthology", "database": "AGR" }, { "id": "HGNC:13276", "url": "https://alliancegenome.org/gene/HGNC:13276#orthology", "database": "AGR" }, { "id": "MGI:108090", "url": 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"homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 297, "end_pos": 299 }, { "start_pos": 6, "end_pos": 8 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { 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"RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608871" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_608871", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608871" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VR42", "url": "https://www.uniprot.org/uniprotkb/Q9VR42" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG3008", "url": "https://www.uniprot.org/uniprotkb/Q9VR42", "locus": { "chromosome": "2L", "start_pos": 4885669, "end_pos": 4883298, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0031643", "url": "https://www.ensemblgenomes.org/id/FBgn0031643" } ] } } ], "crossref": [ { "id": "FB:FBgn0031643", "url": "https://alliancegenome.org/gene/FB:FBgn0031643", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0031643", "url": "https://bgee.org/?page=gene&gene_id=FBgn0031643", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05146", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05146", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0031643", "url": "https://flybase.org/reports/FBgn0031643", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "33693", "url": "https://www.ncbi.nlm.nih.gov/gene/33693", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000687", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000687", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017406", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017406", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018934", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018934", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051272", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051272", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG3008", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3008", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SKCPWGA", "url": "https://omabrowser.org/oma/group/SKCPWGA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VR42", "url": "https://www.orthodb.org/?gene=Q9VR42", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45723", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45723", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01163", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01163", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_608871", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608871", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q9VR42", "url": "https://www.uniprot.org/uniprotkb/Q9VR42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VR42-1", "url": "https://www.uniprot.org/uniprotkb/Q9VR42-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSPWVKTSEPVQQVNLADIMSEQYAHKLHDKELQRHTEKLKRPDEQIAPVWGSQASSPPAPNAQSIQSDAEDWEDYSALLNDEGNVAEDIQLPEDSDAVIAQLLQSQFDHEYNEELRRIERQQNKQSKVTVTLNKFLRDGDAEFLHDTAEDDYEEDELEQQKHDWDRFEDNERQLDSIPRCGFKVNKEGEMITKHDPQLCAVRNAQRVMSFPPEFPTGDAAGFDMKLSNKVFNQLRAHSRRGRSDKHEKVATAEMGLDAGTRLLLYKLINNQILEQINGIISTGKEAVILHANSDANYTGSNEHGHQSGVLVPPQLLPRECAIKIFKTTLNEFKQRDRYIKDDYRFKDRFSKQNHRVIINMWAEKEMHNLMRMQAIGLNVPDVVVLKKHVLVMRFIGDNHNAAPKLKDARLSDAELSCAYEEIVAAMHKLYNEAKLVHADMSEYNILWFEGKCWFIDVAQSVEPKHPSALEFLMRDCGNIVNFFERRGLPNIYTKEQLFEFITGLNSEVHTAAQLEQIHTRGASISQATAPNQEECPDELKPLEYPFELAWEKSQQDRAAQKALQQAQDNNDNKTDTDKDQETDDNENDSDDKEKINKTANH", "length": 603, "header": "tr|Q9VR42-1|Q9VR42_DROME Isoform 1 of Serine/threonine-protein kinase RIO3 OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG3008 PE=1 SV=1 CANONICAL=Q9VR42-1" }, "isoforms": [ { "isoform_ac": "Q9VR42-1", "url": "https://www.uniprot.org/uniprotkb/Q9VR42/entry#Q9VR42-1", "sequence": { "sequence": "MSSPWVKTSEPVQQVNLADIMSEQYAHKLHDKELQRHTEKLKRPDEQIAPVWGSQASSPPAPNAQSIQSDAEDWEDYSALLNDEGNVAEDIQLPEDSDAVIAQLLQSQFDHEYNEELRRIERQQNKQSKVTVTLNKFLRDGDAEFLHDTAEDDYEEDELEQQKHDWDRFEDNERQLDSIPRCGFKVNKEGEMITKHDPQLCAVRNAQRVMSFPPEFPTGDAAGFDMKLSNKVFNQLRAHSRRGRSDKHEKVATAEMGLDAGTRLLLYKLINNQILEQINGIISTGKEAVILHANSDANYTGSNEHGHQSGVLVPPQLLPRECAIKIFKTTLNEFKQRDRYIKDDYRFKDRFSKQNHRVIINMWAEKEMHNLMRMQAIGLNVPDVVVLKKHVLVMRFIGDNHNAAPKLKDARLSDAELSCAYEEIVAAMHKLYNEAKLVHADMSEYNILWFEGKCWFIDVAQSVEPKHPSALEFLMRDCGNIVNFFERRGLPNIYTKEQLFEFITGLNSEVHTAAQLEQIHTRGASISQATAPNQEECPDELKPLEYPFELAWEKSQQDRAAQKALQQAQDNNDNKTDTDKDQETDDNENDSDDKEKINKTANH", "length": 603, "header": "tr|Q9VR42-1|Q9VR42_DROME Isoform 1 of Serine/threonine-protein kinase RIO3 OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG3008 PE=1 SV=1 CANONICAL=Q9VR42-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VR42", "url": "https://www.uniprot.org/uniprotkb/Q9VR42" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VR42", "url": "https://www.uniprot.org/uniprotkb/Q9VR42" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VR42", "url": "https://www.uniprot.org/uniprotkb/Q9VR42" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VR42", "url": "https://www.uniprot.org/uniprotkb/Q9VR42" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VR42", "url": "https://www.uniprot.org/uniprotkb/Q9VR42" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VR42", "url": "https://www.uniprot.org/uniprotkb/Q9VR42" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VR42", "url": "https://www.uniprot.org/uniprotkb/Q9VR42" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VR42", "url": "https://www.uniprot.org/uniprotkb/Q9VR42" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VR42", "url": "https://www.uniprot.org/uniprotkb/Q9VR42" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VR42", "url": "https://www.uniprot.org/uniprotkb/Q9VR42" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VR42", "url": "https://www.uniprot.org/uniprotkb/Q9VR42" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG3008", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3008", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XND6-1", "protein_name": "Serine/threonine-protein kinase RIO3", "gene_name": "RIOK3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MDPVGVAAAAPEAGPGPAWQSKNIYFQCPWGTPKTTSISCSLADVMSEQLAKELQLEEENAAFPEVVAVAEGPFITGENVDTSSDLMLAQMLQMEFDREYDAQLRREEKKFNGDSKVSISFENYRKVHPFDSDSSEDEVDWQDTRHDPYRADKPTITPKKGFIGKGKDITTKHDEVVCGRKNTARMENFAPEFQVGDGIGMDLKLSNQVFNALKQHAYSEERRSARLHEKKEHSTAEKAVDPKTRLLLYKMVSGGMLETITGCISTGKESVVFHAYGGKSATEEDKVIPPECAIKVFKTTLNEFKNRDKYIKDDYRFKDRFSKLNPRKIIRMWAEKEMHNLTRMQNAGIPCPQVVILKKHVLVMSFIGQDQVPAPKLKDVKLNSEDMKKAYYQVLNMMQQLYKECNLVHADLSEYNMLWHDGKVWLIDVSQSVEPTHPHGLEFLFRDCRNVSQFFQKGGVVEALNERELFNAVSGLNITAENEVDFQAEIEALEKMNEDHVQNHGKKVSTFSTDGDPPIYNE", "length": 522 }, "evidence": [ { "id": "Q9VR42", "url": "https://omabrowser.org/oma/group/Q9VR42/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZND9-1", "protein_name": "Serine/threonine-protein kinase RIO3", "gene_name": "Riok3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLVGVSSPEPGPAAAWGPSKCPWATPQNTVSCSLAEVMSEELAKELQLEEEAAAFPEAVVAEGPFISGENMDTSSDLMLAQMLQMEFDREYDAQLRREEKKFNGDSKVSISFENYRKVHPFEDSDSSEDEVDWQDTRDDPYRPAKPVPTPKKGFIGKGKDITTKHDEVVCGRKNTARMENFAPGFQVGDGIGMDLKLSNHVFNALKQHAYSEERRSARLHEKKEHSTAEKAVDPKTRLLMYKMVNSGMLETITGCISTGKESVVFHAYGGSLEDEKEDGKVIPTECAIKVFKTTLNEFKNRDKYIKDDFRFKDRFSKLNPRKIIRMWAEKEMHNLTRMQKAGIPCPTVVLLKKHILVMSFIGHDQVPAPKLKEVKLSEEEMKDAYHQTLHVSSTYHQTLHLMQQLYKECTLVHADLSEYNMLWHAGKVWLIDVSQSVEPTHPHGLEFLFRDCRNVSQFFQKGGVKEALNERELFNAVSGLSISADNEADFLAEIEALEKMNEDHVQKNGRKAASFLKDEGSPPMLYAE", "length": 529 }, "evidence": [ { "id": "RGD:1310833", "url": "https://alliancegenome.org/gene/RGD:1310833#orthology", "database": "AGR" }, { "id": "MGI:1914128", "url": "https://alliancegenome.org/gene/MGI:1914128#orthology", "database": "AGR" }, { "id": "HGNC:11451", "url": "https://alliancegenome.org/gene/HGNC:11451#orthology", "database": "AGR" }, { "id": "FB:FBgn0031643", "url": "https://alliancegenome.org/gene/FB:FBgn0031643#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O14730-1", "protein_name": "Serine/threonine-protein kinase RIO3", "gene_name": "RIOK3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDLVGVASPEPGTAAAWGPSKCPWAIPQNTISCSLADVMSEQLAKELQLEEEAAVFPEVAVAEGPFITGENIDTSSDLMLAQMLQMEYDREYDAQLRREEKKFNGDSKVSISFENYRKVHPYEDSDSSEDEVDWQDTRDDPYRPAKPVPTPKKGFIGKGKDITTKHDEVVCGRKNTARMENFAPEFQVGDGIGMDLKLSNHVFNALKQHAYSEERRSARLHEKKEHSTAEKAVDPKTRLLMYKMVNSGMLETITGCISTGKESVVFHAYGGSMEDEKEDSKVIPTECAIKVFKTTLNEFKNRDKYIKDDFRFKDRFSKLNPRKIIRMWAEKEMHNLARMQRAGIPCPTVVLLKKHILVMSFIGHDQVPAPKLKEVKLNSEEMKEAYYQTLHLMRQLYHECTLVHADLSEYNMLWHAGKVWLIDVSQSVEPTHPHGLEFLFRDCRNVSQFFQKGGVKEALSERELFNAVSGLNITADNEADFLAEIEALEKMNEDHVQKNGRKAASFLKDDGDPPLLYDE", "length": 519 }, "evidence": [ { "id": "RGD:1310833", "url": "https://alliancegenome.org/gene/RGD:1310833#orthology", "database": "AGR" }, { "id": "MGI:1914128", "url": "https://alliancegenome.org/gene/MGI:1914128#orthology", "database": "AGR" }, { "id": "HGNC:11451", "url": "https://alliancegenome.org/gene/HGNC:11451#orthology", "database": "AGR" }, { "id": "FB:FBgn0031643", "url": "https://alliancegenome.org/gene/FB:FBgn0031643#orthology", "database": "AGR" }, { "id": "Q9VR42", "url": "https://omabrowser.org/oma/group/Q9VR42/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q1RMT7-1", "protein_name": "Serine/threonine-protein kinase RIO3", "gene_name": "RIOK3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDLVRVASPEPGPAAAWGPNKCPWATPQNTISCSLSDVMSEQLAKELQLEEEAAAFPEVTVAEGPFITGENIDTSSDLMLAQMLQMEFDREYDAQLRREEKKFNGDSKVCISFENYRKVHPYEDSDSSEDEVDWQDTRDDPYRPAKPIPTPKKGFIGKGKDITTKHDEVVCGRKNTARMENFAPGFQVGDGIGMDLKLSNHVFNALKQHAYSEERRSARLHEKKEHSTAEKAVDPKTRLLMYKMVNSGMLETITGCISTGKESVVFHAYGGSMEDGKEDSKVIPTECAIKVFKTTLNEFKNRDKYIKDDFRFKDRFSKLNPRKIIRMWAEKEMHNLTRMQRAGIPCPTVVLLKKHILVMSFIGHDQVPAPKLKEVKLSSEEMKDAYYQTLHLMQQLYDECTLVHADLSEYNMLWHAGKVWLIDVSQSVEPTHPHGLEFLFRDCRNVSQFFQKGGVKEALGERELFNAVSGLNISADNEADFLAEIEALEKMNEDHVQKNGRKAASFLKDDGGPPILYDE", "length": 519 }, "evidence": [ { "id": "Q9VR42", "url": "https://omabrowser.org/oma/group/Q9VR42/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9DBU3-1", "protein_name": "Serine/threonine-protein kinase RIO3", "gene_name": "Riok3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLVGVSSPEPGPAAAWGPSKCPWATPQNTVSCSLTEVMSEELAKELQLEEEAAAFPEVVVAEGPFISGENIDTSSDLMLAQMLQMEFDREYDAQLRREEKKFNGDSKVSISFENYRKVHPFEDSDSSEDEVDWQDTRDDPYRPAKPIPTPKKGFIGKGKDITTKHDEVVCGRKNTARMENFAPGFQVGDGIGMDLKLSNHVFNALKQHAYSEERRSARLHEKKEHSTAEKAVDPKTRLLMYKMVNSGMLETITGCISTGKESVVFHAYGGSLEDEKEDGKAIPTECAIKVFKTTLNEFKNRDKYIKDDFRFKDRFSKLNPRKIIRMWAEKEMHNLTRMQKAGIPCPTVVLLKKHILVMSFIGHDQVPAPKLKEVKLSNEEMKDAYYQTLHLMQQLYNECTLVHADLSEYNMLWHAGKVWLIDVSQSVEPTHPHGLEFLFRDCRNVSQFFQKGGVTEALNERELFNAVSGLNISADNEADFLAEIEALEKMNEDHIQKNGRKAASFLKDDGSPPVLSAD", "length": 519 }, "evidence": [ { "id": "RGD:1310833", "url": "https://alliancegenome.org/gene/RGD:1310833#orthology", "database": "AGR" }, { "id": "MGI:1914128", "url": "https://alliancegenome.org/gene/MGI:1914128#orthology", "database": "AGR" }, { "id": "HGNC:11451", "url": "https://alliancegenome.org/gene/HGNC:11451#orthology", "database": "AGR" }, { "id": "FB:FBgn0031643", "url": "https://alliancegenome.org/gene/FB:FBgn0031643#orthology", "database": "AGR" }, { "id": "Q9VR42", "url": "https://omabrowser.org/oma/group/Q9VR42/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "Q9VR42", "url": "https://www.uniprot.org/uniprotkb/Q9VR42" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "Q9VR42", "url": "https://www.uniprot.org/uniprotkb/Q9VR42" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VR42", "url": "https://www.uniprot.org/uniprotkb/Q9VR42" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VR42", "url": "https://www.uniprot.org/uniprotkb/Q9VR42" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VR42", "url": "https://www.uniprot.org/uniprotkb/Q9VR42" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VR42", "url": "https://www.uniprot.org/uniprotkb/Q9VR42" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VR42", "url": "https://www.uniprot.org/uniprotkb/Q9VR42" } ], "pmid": "" }, { "name": "preribosome, small subunit precursor", "id": "GO:0030688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030688", "evidence": [ { "database": "UniProtKB", "id": "Q9VR42", "url": "https://www.uniprot.org/uniprotkb/Q9VR42" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "maturation of SSU-rRNA", "id": "GO:0030490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030490", "evidence": [ { "database": "UniProtKB", "id": "Q9VR42", "url": "https://www.uniprot.org/uniprotkb/Q9VR42" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 298, "end_pos": 300, "annotation": "n_glycosylation_sequon" }, { "start_pos": 574, "end_pos": 576, "annotation": "n_glycosylation_sequon" }, { "start_pos": 589, "end_pos": 591, "annotation": "n_glycosylation_sequon" }, { "start_pos": 598, "end_pos": 600, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O61267-1", "P13677-1", "P23573-1", "P51123-1", "Q00168-1", "Q23977-1", "Q24210-3", "Q9VKN7-1", "O62618-1", "P10676-1", "P18431-2", "P23647-1", "P52304-1", "P83104-1", "Q03042-1", "Q70PP2-1", "Q8T0S6-1", "P83099-1", "Q9NIV1-1", "O76324-1", "P13678-1", "P16912-1", "P23572-1", "P40417-3", "P48609-1", "P49071-1", "P54367-1", "P83100-1", "P83102-1", "P92208-1", "Q03043-1", "Q0KHT7-1", "Q24324-1", "Q5EAK6-1", "P12370-1", "Q05652-1", "Q9VXE5-1", "P83103-1", "P54360-1", "Q7KRY6-1", "Q95UN8-1", "Q8INB9-1", "Q8IMC6-1", "Q8IR79-1", "Q9V3D5-1", "Q7PLI7-1", "A1Z9X0-1", "P08181-1", "P11346-1", "O61661-1", "A1ZBH7-1", "Q9VM90-1", "P49762-1", "A0A0B4KHX7-1", "M9PI41-1", "Q9W002-1", "Q9VPC0-1", "Q9VXG8-1", "Q9W354-1", "A1Z7T0-1", "O61443-1", "O97143-1", "P05130-1", "P16911-1", "P49657-1", "Q9NI63-1", "Q9V3Q6-1", "Q9VA38-1", "Q9VK45-1", "Q9W0V1-4", "Q9VT57-1", "Q9VI13-1", "Q0KHQ5-1", "Q0KHV6-1", "Q9NBK5-1", "A4VCL2-2", "Q9VP22-1", "Q9W1B0-1", "Q9V3I5-1", "A8JR46-1", "A0A126GUV7-1", "X2JAG8-1", "A0A0B4KHT3-1", "A1ZBC4-1", "A0A4D6K823-1", "A1ZBL9-1", "Q9VBU2-1", "Q9VL34-1", "M9PGC5-1", "Q9VUV4-1", "A0A6M3Q7C8-1", "Q9VE06-1", "Q9VMY8-1", "Q9VUQ9-1", "Q9VR61-1", "Q9VRJ6-1", "Q9VW24-1", "Q9VTL5-1", "Q9VJ30-1", "M9MS50-1", "Q94533-1", "Q9VGF9-1", "Q9VXN5-1", "Q9VD82-1", "Q24216-1", "Q9VR42-1", "Q9VI84-1", "A0A0B4KHL4-1", "A0A6M3Q6U2-1", "M9PE01-1", "B7Z126-1", "Q9VMN3-1", "Q9VEN3-1", "O18645-1", "Q9W3N8-1", "Q9VGI4-1", "Q9VHF6-1", "Q24171-1", "Q9VL64-1", "Q9VJ90-1", "Q9W532-1", "Q9VGP9-1", "Q9VGQ0-1", "Q9VPW3-1", "A4V2C3-1", "Q9W3Y1-1", "Q0E981-1", "Q9VXE3-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O61267-1", "P13677-1", "P23573-1", "P51123-1", "Q00168-1", "Q23977-1", "Q24210-3", "Q9VKN7-1", "O62618-1", "P10676-1", "P18431-2", "P23647-1", "P52304-1", "P83104-1", "Q03042-1", "Q70PP2-1", "Q8T0S6-1", "O76324-1", "P13678-1", "P16912-1", "P23572-1", "P40417-3", "P48609-1", "P49071-1", "P54367-1", "P83099-1", "P83100-1", "P83102-1", "P92208-1", "Q03043-1", "Q0KHT7-1", "Q24324-1", "Q5EAK6-1", "Q9NIV1-1", "P12370-1", "Q05652-1", "Q9VXE5-1", "P83103-1", "P54360-1", "Q7KRY6-1", "Q95UN8-1", "Q8INB9-1", "Q8IMC6-1", "Q8IR79-1", "Q9V3D5-1", "Q7PLI7-1", "A1Z9X0-1", "P08181-1", "P11346-1", "O61661-1", "Q9VM90-1", "A1ZBL9-1", "P49762-1", "A0A0B4KHX7-1", "M9PI41-1", "Q9VPC0-1", "Q9VXG8-1", "Q9W354-1", "A1Z7T0-1", "O61443-1", "O97143-1", "P05130-1", "P16911-1", "P49657-1", "Q9NI63-1", "Q9V3Q6-1", "Q9VA38-1", "Q9VK45-1", "Q9W0V1-4", "Q9VT57-1", "Q9VI13-1", "Q0KHQ5-1", "Q0KHV6-1", "Q9NBK5-1", "A4VCL2-2", "A1ZBH7-1", "Q9VP22-1", "Q9VZI2-1", "Q9W1B0-1", "Q9V3I5-1", "A8JR46-1", "A0A126GUV7-1", "X2JAG8-1", "A0A0B4KHC3-1", "A0A0B4KHT3-1", "A1ZBC4-1", "A0A4D6K823-1", "Q9I7F7-1", "Q9VBU2-1", "Q9W002-1", "Q9VL34-1", "M9PGC5-1", "Q9VUV4-1", "A0A6M3Q7C8-1", "Q9VE06-1", "Q9VMY8-1", "Q9VUQ9-1", "Q9VR61-1", "Q9VRJ6-1", "Q9VW24-1", "Q9VTL5-1", "Q9VJ30-1", "M9MS50-1", "Q94533-1", "Q9VGF9-1", "Q9VXN5-1", "Q9VD82-1", "Q24216-1", "Q9VR42-1", "Q9VI84-1", "A0A0B4KHL4-1", "A0A6M3Q6U2-1", "M9PE01-1", "B7Z126-1", "Q9VMN3-1", "Q9VEN3-1", "O18645-1", "Q9W3N8-1", "Q9VGI4-1", "Q9VHF6-1", "Q24171-1", "Q9VL64-1", "Q9VJ90-1", "Q9W532-1", "Q9VGP9-1", "Q9VGQ0-1", "Q9VPW3-1", "A4V2C3-1", "Q9W3Y1-1", "Q0E981-1", "Q9VXE3-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A0B4KHC3", "gene_name": "PKD", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A0B4KHC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHC3" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A0B4KHC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHC3" } ] }, { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A0B4KHC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHC3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A0B4KHC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHC3" } ] } ] }, { "uniprot_ac": "A0A0B4KHL4", "gene_name": "gish", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A0B4KHL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHL4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0B4KHL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHL4" } ] } ] }, { "uniprot_ac": "A0A0B4KHT3", "gene_name": "Lrrk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A0B4KHT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0B4KHT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHT3" } ] } ] }, { "uniprot_ac": "A0A0B4KHX7", "gene_name": "Gcn2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A0B4KHX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHX7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0B4KHX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHX7" } ] } ] }, { "uniprot_ac": "A0A126GUV7", "gene_name": "fray", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A126GUV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A126GUV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A126GUV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A126GUV7" } ] } ] }, { "uniprot_ac": "A0A4D6K823", "gene_name": "nmo", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A4D6K823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K823" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A4D6K823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K823" } ] } ] }, { "uniprot_ac": "A0A6M3Q6U2", "gene_name": "Hipk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A6M3Q6U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A6M3Q6U2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A6M3Q6U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A6M3Q6U2" } ] } ] }, { "uniprot_ac": "A0A6M3Q7C8", "gene_name": "SRPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A6M3Q7C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A6M3Q7C8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A6M3Q7C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A6M3Q7C8" } ] } ] }, { "uniprot_ac": "A1Z7T0", "gene_name": "Pkn", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1Z7T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1Z7T0" } ] }, { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1Z7T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1Z7T0" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1Z7T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1Z7T0" } ] } ] }, { "uniprot_ac": "A1Z9X0", "gene_name": "aPKC", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1Z9X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1Z9X0" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1Z9X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1Z9X0" } ] } ] }, { "uniprot_ac": "A1ZBC4", "gene_name": "Sik3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1ZBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1ZBC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A1ZBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1ZBC4" } ] } ] }, { "uniprot_ac": "A1ZBH7", "gene_name": "hppy", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1ZBH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1ZBH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A1ZBH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1ZBH7" } ] } ] }, { "uniprot_ac": "A1ZBL9", "gene_name": "par-1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1ZBL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1ZBL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A1ZBL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1ZBL9" } ] } ] }, { "uniprot_ac": "A4V2C3", "gene_name": "Dmel\\CG17698", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A4V2C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4V2C3" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A4V2C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4V2C3" } ] } ] }, { "uniprot_ac": "A4VCL2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A4VCL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4VCL2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A4VCL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4VCL2" } ] } ] }, { "uniprot_ac": "A8JR46", "gene_name": "Ire1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A8JR46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8JR46" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A8JR46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8JR46" } ] } ] }, { "uniprot_ac": "B7Z126", "gene_name": "Tlk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "B7Z126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B7Z126" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "B7Z126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B7Z126" } ] } ] }, { "uniprot_ac": "M9MS50", "gene_name": "Srpk79D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "M9MS50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9MS50" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "M9MS50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9MS50" } ] } ] }, { "uniprot_ac": "M9PE01", "gene_name": "Eip63E", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "M9PE01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9PE01" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "M9PE01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9PE01" } ] } ] }, { "uniprot_ac": "M9PGC5", "gene_name": "Wnk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "M9PGC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9PGC5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "M9PGC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9PGC5" } ] } ] }, { "uniprot_ac": "M9PI41", "gene_name": "sti", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "M9PI41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9PI41" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "M9PI41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9PI41" } ] } ] }, { "uniprot_ac": "O18645", "gene_name": "AMPKalpha", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "O18645", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O18645" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O18645", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O18645" } ] } ] }, { "uniprot_ac": "O61267", "gene_name": "lok", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "O61267", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O61267" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O61267", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O61267" } ] } ] }, { "uniprot_ac": "O61443", "gene_name": "p38b", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "O61443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O61443" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "O61443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O61443" } ] } ] }, { "uniprot_ac": "O61661", "gene_name": "grp", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "O61661", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O61661" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O61661", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O61661" } ] } ] }, { "uniprot_ac": "O62618", "gene_name": "p38a", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "O62618", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O62618" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "O62618", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O62618" } ] } ] }, { "uniprot_ac": "O76324", "gene_name": "dco", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "O76324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O76324" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O76324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O76324" } ] } ] }, { "uniprot_ac": "O97143", "gene_name": "SAK", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "O97143", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O97143" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "O97143", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O97143" } ] } ] }, { "uniprot_ac": "P05130", "gene_name": "Pkc53E", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05130", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05130" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05130", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05130" } ] } ] }, { "uniprot_ac": "P08181", "gene_name": "CkIIalpha", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P08181", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08181" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P08181", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08181" } ] } ] }, { "uniprot_ac": "P10676", "gene_name": "ninaC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P10676", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10676" } ] }, { "ec_number": "5.6.1.8", "activity": "ATP + H2O + myosin bound to actin filament at position(n) = ADP + phosphate + myosin bound to actin filament at position(n+1).", "evidence": [ { "id": "P10676", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10676" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P10676", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10676" } ] } ] }, { "uniprot_ac": "P11346", "gene_name": "Raf", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P11346", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11346" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P11346", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11346" } ] } ] }, { "uniprot_ac": "P12370", "gene_name": "Pka-C1", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P12370", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P12370" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P12370", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P12370" } ] } ] }, { "uniprot_ac": "P13677", "gene_name": "inaC", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13677", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13677" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P13677", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13677" } ] } ] }, { "uniprot_ac": "P13678", "gene_name": "Pkc98E", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13678", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13678" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P13678", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13678" } ] } ] }, { "uniprot_ac": "P16911", "gene_name": "Pka-C2", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P16911", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P16911" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P16911", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P16911" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P16911", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P16911" } ] } ] }, { "uniprot_ac": "P16912", "gene_name": "Pka-C3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P16912", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P16912" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P16912", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P16912" } ] } ] }, { "uniprot_ac": "P18431", "gene_name": "sgg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18431", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18431" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P18431", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18431" } ] } ] }, { "uniprot_ac": "P23572", "gene_name": "Cdk1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P23572", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P23572" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P23572", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P23572" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P23572", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P23572" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P23572", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P23572" } ] } ] }, { "uniprot_ac": "P23573", "gene_name": "Cdk2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P23573", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P23573" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P23573", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P23573" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P23573", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P23573" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P23573", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P23573" } ] } ] }, { "uniprot_ac": "P23647", "gene_name": "fu", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P23647", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P23647" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P23647", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P23647" } ] } ] }, { "uniprot_ac": "P40417", "gene_name": "rl", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P40417", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P40417" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P40417", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P40417" } ] } ] }, { "uniprot_ac": "P48609", "gene_name": "Cdk5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48609", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48609" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48609", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48609" } ] } ] }, { "uniprot_ac": "P49071", "gene_name": "MAPk-Ak2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P49071", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P49071" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P49071", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P49071" } ] } ] }, { "uniprot_ac": "P49657", "gene_name": "mnb", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P49657", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P49657" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "P49657", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P49657" } ] } ] }, { "uniprot_ac": "P49762", "gene_name": "Doa", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P49762", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P49762" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "P49762", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P49762" } ] } ] }, { "uniprot_ac": "P51123", "gene_name": "Taf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P51123", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P51123" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P51123", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P51123" } ] } ] }, { "uniprot_ac": "P52304", "gene_name": "polo", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52304", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52304" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "P52304", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52304" } ] } ] }, { "uniprot_ac": "P54360", "gene_name": "fj", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P54360", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P54360" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P54360", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P54360" } ] } ] }, { "uniprot_ac": "P54367", "gene_name": "CkIalpha", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P54367", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P54367" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P54367", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P54367" } ] } ] }, { "uniprot_ac": "P83099", "gene_name": "Pkcdelta", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P83099", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P83099" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P83099", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P83099" } ] } ] }, { "uniprot_ac": "P83100", "gene_name": "p38c", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P83100", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P83100" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P83100", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P83100" } ] } ] }, { "uniprot_ac": "P83102", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P83102", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P83102" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "P83102", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P83102" } ] } ] }, { "uniprot_ac": "P83103", "gene_name": "Haspin", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P83103", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P83103" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P83103", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P83103" } ] } ] }, { "uniprot_ac": "P83104", "gene_name": "Takl1", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P83104", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P83104" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "P83104", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P83104" } ] } ] }, { "uniprot_ac": "P92208", "gene_name": "bsk", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P92208", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P92208" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P92208", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P92208" } ] } ] }, { "uniprot_ac": "Q00168", "gene_name": "CaMKII", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q00168", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q00168" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q00168", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q00168" } ] } ] }, { "uniprot_ac": "Q03042", "gene_name": "Pkg21D", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q03042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q03042" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "Q03042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q03042" } ] } ] }, { "uniprot_ac": "Q03043", "gene_name": "for", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q03043", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q03043" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "Q03043", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q03043" } ] } ] }, { "uniprot_ac": "Q05652", "gene_name": "pll", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q05652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05652" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q05652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05652" } ] } ] }, { "uniprot_ac": "Q0E981", "gene_name": "Snrk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0E981", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0E981" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0E981", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0E981" } ] } ] }, { "uniprot_ac": "Q0KHQ5", "gene_name": "Tao", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0KHQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0KHQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0KHQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0KHQ5" } ] } ] }, { "uniprot_ac": "Q0KHT7", "gene_name": "Drak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0KHT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0KHT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0KHT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0KHT7" } ] } ] }, { "uniprot_ac": "Q0KHV6", "gene_name": "Pink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0KHV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0KHV6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0KHV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0KHV6" } ] } ] }, { "uniprot_ac": "Q23977", "gene_name": "hep", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q23977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q23977" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q23977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q23977" } ] } ] }, { "uniprot_ac": "Q24171", "gene_name": "ksr", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q24171", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q24171" } ] } ] }, { "uniprot_ac": "Q24210", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q24210", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q24210" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q24210", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q24210" } ] } ] }, { "uniprot_ac": "Q24216", "gene_name": "Cdk7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q24216", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q24216" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "Q24216", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q24216" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q24216", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q24216" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q24216", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q24216" } ] } ] }, { "uniprot_ac": "Q24324", "gene_name": "Dsor1", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q24324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q24324" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q24324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q24324" } ] } ] }, { "uniprot_ac": "Q5EAK6", "gene_name": "tefu", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5EAK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAK6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5EAK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAK6" } ] } ] }, { "uniprot_ac": "Q70PP2", "gene_name": "nonC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q70PP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q70PP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q70PP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q70PP2" } ] } ] }, { "uniprot_ac": "Q7KRY6", "gene_name": "ball", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q7KRY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7KRY6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7KRY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7KRY6" } ] } ] }, { "uniprot_ac": "Q7PLI7", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q7PLI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7PLI7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7PLI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7PLI7" } ] } ] }, { "uniprot_ac": "Q8IMC6", "gene_name": "Asator", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8IMC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8IMC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8IMC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8IMC6" } ] } ] }, { "uniprot_ac": "Q8INB9", "gene_name": "Akt", 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"evidence": [ { "id": "Q9NBK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9NBK5" } ] } ] }, { "uniprot_ac": "Q9NI63", "gene_name": "Myt1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9NI63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9NI63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9NI63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9NI63" } ] } ] }, { "uniprot_ac": "Q9NIV1", "gene_name": "PEK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9NIV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9NIV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9NIV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9NIV1" } ] } ] }, { "uniprot_ac": "Q9V3D5", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9V3D5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9V3D5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q9V3D5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9V3D5" } ] } ] }, { "uniprot_ac": "Q9V3I5", "gene_name": "JIL-1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9V3I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9V3I5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9V3I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9V3I5" } ] } ] }, { "uniprot_ac": "Q9V3Q6", "gene_name": "Tak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9V3Q6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9V3Q6" } ] }, { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9V3Q6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9V3Q6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q9V3Q6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9V3Q6" } ] } ] }, { "uniprot_ac": "Q9VA38", "gene_name": "wts", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9VA38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VA38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VA38", "database": "UniProtKB", "url": 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"cdi", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9VE06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VE06" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q9VE06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VE06" } ] } ] }, { "uniprot_ac": "Q9VEN3", "gene_name": "GckIII", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9VEN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VEN3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VEN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VEN3" } ] } ] }, { "uniprot_ac": "Q9VGF9", "gene_name": "aurA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9VGF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VGF9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VGF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VGF9" } ] } ] }, { "uniprot_ac": "Q9VGI4", "gene_name": "Lk6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9VGI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VGI4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VGI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VGI4" } ] } ] }, { "uniprot_ac": "Q9VGP9", "gene_name": "KP78a", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9VGP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VGP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VGP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VGP9" } ] } ] }, { "uniprot_ac": "Q9VGQ0", "gene_name": "KP78b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9VGQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VGQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VGQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VGQ0" } ] } ] }, { "uniprot_ac": "Q9VHF6", "gene_name": "Aduk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9VHF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VHF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VHF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VHF6" } ] } ] }, { "uniprot_ac": "Q9VI13", "gene_name": "Pak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9VI13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VI13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VI13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VI13" } ] } ] }, { "uniprot_ac": "Q9VI84", "gene_name": "Dmel\\CG1227", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9VI84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VI84" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VI84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VI84" } ] } ] }, { "uniprot_ac": "Q9VJ30", "gene_name": "Nak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9VJ30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJ30" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VJ30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJ30" } ] } ] }, { "uniprot_ac": "Q9VJ90", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9VJ90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJ90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VJ90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJ90" } ] } ] }, { "uniprot_ac": "Q9VK45", "gene_name": "mTor", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9VK45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VK45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VK45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VK45" } ] } ] }, { "uniprot_ac": "Q9VKN7", "gene_name": "aurB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9VKN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VKN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VKN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VKN7" } ] } ] }, { "uniprot_ac": "Q9VL34", "gene_name": "Dmel\\CG4839", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9VL34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VL34" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "Q9VL34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VL34" } ] } ] }, { "uniprot_ac": "Q9VL64", "gene_name": "IME2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9VL64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VL64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VL64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VL64" } ] } ] }, { "uniprot_ac": "Q9VM90", "gene_name": "meng", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9VM90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VM90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VM90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VM90" } ] } ] }, { "uniprot_ac": "Q9VMN3", "gene_name": "Cdkl", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9VMN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMN3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q9VMN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMN3" } ] } ] }, { "uniprot_ac": "Q9VMY8", "gene_name": "aux", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9VMY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VMY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMY8" } ] } ] }, { "uniprot_ac": "Q9VP22", "gene_name": "Cdk12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9VP22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VP22" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "Q9VP22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VP22" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q9VP22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VP22" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q9VP22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VP22" } ] } ] }, { "uniprot_ac": "Q9VPC0", "gene_name": "Pitslre", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9VPC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPC0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q9VPC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPC0" } ] } ] }, { "uniprot_ac": "Q9VPW3", "gene_name": "anon-WO0257455.15", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9VPW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPW3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VPW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VPW3" } ] } ] }, { "uniprot_ac": "Q9VR42", "gene_name": "Dmel\\CG3008", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9VR42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VR42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VR42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VR42" } ] } ] }, { "uniprot_ac": "Q9VR61", "gene_name": "S6kII", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9VR61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VR61" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VR61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VR61" } ] } ] }, { "uniprot_ac": "Q9VRJ6", "gene_name": "Tcs5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9VRJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VRJ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VRJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VRJ6" } ] } ] }, { "uniprot_ac": "Q9VT57", "gene_name": "Cdk8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9VT57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VT57" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "Q9VT57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VT57" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q9VT57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VT57" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q9VT57", "database": "UniProtKB", "url": 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"activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9VUV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUV4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VUV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUV4" } ] } ] }, { "uniprot_ac": "Q9VW24", "gene_name": "wnd", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9VW24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VW24" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q9VW24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VW24" } ] } ] }, { "uniprot_ac": "Q9VXE3", "gene_name": "Rok", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] 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{ "id": "X2JAG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/X2JAG8" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VR42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VR42" }, { "id": "SM00090", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00090" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RIO kinase", "eco_id": "ECO_0000259", "start_pos": 247, "end_pos": 505, "start_aa": "Lys", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.11.1", "ec_name": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "2.7.11.1", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1" }, { "id": "2.7.11.1", "database": "BRENDA Enzymes", "url": 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"sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"https://www.ncbi.nlm.nih.gov/protein/NP_608470" }, "gene_names": [ { "name": "Cluap1", "type": "recommended", "evidence": [ { "id": "Q9VR64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VR64" } ] }, { "name": "CG17599", "type": "synonym", "evidence": [ { "id": "NP_608470", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608470" }, { "id": "Q9VR64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VR64" } ] }, { "name": "CLUAP1", "type": "synonym", "evidence": [ { "id": "NP_608470", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608470" }, { "id": "Q9VR64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VR64" } ] }, { "name": "Cluap1", "type": "synonym", "evidence": [ { "id": "NP_608470", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608470" } ] }, { "name": "Dmel\\CG17599", "type": "synonym", "evidence": [ { "id": "NP_608470", "database": "RefSeq", 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"https://www.ncbi.nlm.nih.gov/protein/NP_608470" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VR64", "url": "https://www.uniprot.org/uniprotkb/Q9VR64" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Cluap1", "url": "https://www.uniprot.org/uniprotkb/Q9VR64", "locus": { "chromosome": "X", "start_pos": 22542386, "end_pos": 22544322, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0031196", "url": "https://www.ensemblgenomes.org/id/FBgn0031196" } ] } } ], "crossref": [ { "id": "FB:FBgn0031196", "url": "https://alliancegenome.org/gene/FB:FBgn0031196", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0031196", "url": "https://bgee.org/?page=gene&gene_id=FBgn0031196", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0031196", "url": "https://flybase.org/reports/FBgn0031196", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "33142", "url": "https://www.ncbi.nlm.nih.gov/gene/33142", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VR64", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VR64*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR019366", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019366", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG17599", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG17599", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RIRPAHM", "url": "https://omabrowser.org/oma/group/RIRPAHM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VR64", "url": "https://www.orthodb.org/?gene=Q9VR64", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21547", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21547", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21547:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21547:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10234", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10234", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_608470", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608470", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VR64", "url": "https://www.uniprot.org/uniprotkb/Q9VR64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VR64-1", "url": "https://www.uniprot.org/uniprotkb/Q9VR64-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSFKDVRDLGEHLKLLGFPRVFPLQSLANQHGSLASFHIVAELLQWLAGLIEPGATLPGGVESEEQRVLLVRSATEFFVTKAAIRINPRKLYAAAAVTAAELQKVTRLLTSPGQNEADNDEEDQRDQYRSLNPVDIGDKIEELRKARELATDLTQRGTTICEMLSKELLHKESLMSQAQRPLELLSVERTLKSAIQANQVRLQSSRAQLEAAKVELNALGSKLQRRRAELERTRQRLEALHRIRPAHMAEFEDCEKELQELFQRYFLRLHVRDALKSQLDLRTKRATPISSPILQKPAENSMPFIPEGLIEDDDDDDDEDDLDDEDEGDDGGKALSRLEMVVNGRSVFGLDSEIPDIRDEDKLMQQNNMVSAQGKRPGTATSRIRPTTGRSRKAVGGRGTAGPDGGNDARAARGTRRGVATGGDADGTQLNGRNGPGSSMLNSRDEDSSFGSSESELDVGKIMGMSGMSGMSGMSAISGISGMSNIALGAGDDDFDLNSIDDISISKLTGELPLRPKTANKAEHHSDEDF", "length": 530, "header": "tr|Q9VR64-1|Q9VR64_DROME Isoform 1 of Clusterin associated protein 1 OS=Drosophila melanogaster OX=7227 GN=Cluap1 PE=3 SV=1 CANONICAL=Q9VR64-1" }, "isoforms": [ { "isoform_ac": "Q9VR64-1", "url": "https://www.uniprot.org/uniprotkb/Q9VR64/entry#Q9VR64-1", "sequence": { "sequence": "MSFKDVRDLGEHLKLLGFPRVFPLQSLANQHGSLASFHIVAELLQWLAGLIEPGATLPGGVESEEQRVLLVRSATEFFVTKAAIRINPRKLYAAAAVTAAELQKVTRLLTSPGQNEADNDEEDQRDQYRSLNPVDIGDKIEELRKARELATDLTQRGTTICEMLSKELLHKESLMSQAQRPLELLSVERTLKSAIQANQVRLQSSRAQLEAAKVELNALGSKLQRRRAELERTRQRLEALHRIRPAHMAEFEDCEKELQELFQRYFLRLHVRDALKSQLDLRTKRATPISSPILQKPAENSMPFIPEGLIEDDDDDDDEDDLDDEDEGDDGGKALSRLEMVVNGRSVFGLDSEIPDIRDEDKLMQQNNMVSAQGKRPGTATSRIRPTTGRSRKAVGGRGTAGPDGGNDARAARGTRRGVATGGDADGTQLNGRNGPGSSMLNSRDEDSSFGSSESELDVGKIMGMSGMSGMSGMSAISGISGMSNIALGAGDDDFDLNSIDDISISKLTGELPLRPKTANKAEHHSDEDF", "length": 530, "header": "tr|Q9VR64-1|Q9VR64_DROME Isoform 1 of Clusterin associated protein 1 OS=Drosophila melanogaster OX=7227 GN=Cluap1 PE=3 SV=1 CANONICAL=Q9VR64-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 98, "start_aa": "Thr", "end_pos": 98, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr98", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VR64", "url": "https://www.uniprot.org/uniprotkb/Q9VR64" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VR64", "url": "https://www.uniprot.org/uniprotkb/Q9VR64" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VR64", "url": "https://www.uniprot.org/uniprotkb/Q9VR64" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VR64", "url": "https://www.uniprot.org/uniprotkb/Q9VR64" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VR64", "url": "https://www.uniprot.org/uniprotkb/Q9VR64" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VR64", "url": "https://www.uniprot.org/uniprotkb/Q9VR64" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VR64", "url": "https://www.uniprot.org/uniprotkb/Q9VR64" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VR64", "url": "https://www.uniprot.org/uniprotkb/Q9VR64" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VR64", "url": "https://www.uniprot.org/uniprotkb/Q9VR64" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VR69-1", "uniprot_ac": "Q9VR69", "uniprot_id": "Q9VR69_DROME", "mass": { "chemical_mass": 55417.0, "monoisotopic_mass": 55417.0 }, "refseq": { "ac": "NP_728468", "name": "chitin deacetylase-like 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_728468" }, "gene_names": [ { "name": "Cda4", "type": "recommended", "evidence": [ { "id": "Q9VR69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VR69" } ] }, { "name": "BcDNA:RE51076", "type": "synonym", "evidence": [ { "id": "NP_728468", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_728468" }, { "id": "Q9VR69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VR69" } ] }, { "name": "CG12447", "type": "synonym", "evidence": [ { "id": "NP_728468", "database": "RefSeq", "url": 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"database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_728468" }, { "id": "Q9VR69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VR69" } ] }, { "name": "Cda4", "type": "synonym", "evidence": [ { "id": "NP_728468", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_728468" } ] }, { "name": "DmCDA4", "type": "synonym", "evidence": [ { "id": "NP_728468", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_728468" }, { "id": "Q9VR69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VR69" } ] }, { "name": "Dmel\\CG32499", "type": "synonym", "evidence": [ { "id": "NP_728468", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_728468" }, { "id": "Q9VR69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VR69" } ] }, { "name": "Dmel_CG32499", "type": "synonym", "evidence": [ { "id": "Q9VR69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VR69" } ] } ], "protein_names": [ { "name": "CG32499-PA", "type": "synonym", "evidence": [ { "id": "NP_728468", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_728468" } ] }, { "name": "Cda4-PA", "type": "synonym", "evidence": [ { "id": "NP_728468", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_728468" } ] }, { "name": "Chitin deacetylase-like 4", "type": "synonym", "evidence": [ { "id": "Q9VR69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VR69/entry#names_and_taxonomy" } ] }, { "name": "chitin deacetylase-like 4", "type": "synonym", "evidence": [ { "id": "NP_728468", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_728468" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VR69", "url": "https://www.uniprot.org/uniprotkb/Q9VR69" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Cda4", "url": "https://www.uniprot.org/uniprotkb/Q9VR69", "locus": { "chromosome": "X", "start_pos": 22583634, "end_pos": 22632710, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0052499", "url": "https://www.ensemblgenomes.org/id/FBgn0052499" } ] } } ], "crossref": [ { "id": "FB:FBgn0052499", "url": "https://alliancegenome.org/gene/FB:FBgn0052499", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0052499", "url": "https://bgee.org/?page=gene&gene_id=FBgn0052499", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd10974", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10974", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0052499", "url": "https://flybase.org/reports/FBgn0052499", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "33144", "url": "https://www.ncbi.nlm.nih.gov/gene/33144", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VR69", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VR69*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR002557", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002557", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011330", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011330", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036508", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036508", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052740", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052740", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG32499", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG32499", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EQNRAPY", "url": "https://omabrowser.org/oma/group/EQNRAPY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VR69", "url": "https://www.orthodb.org/?gene=Q9VR69", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45985", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45985", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45985:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45985:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01607", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01607", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_728468", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_728468", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VR69", "url": "https://www.uniprot.org/uniprotkb/Q9VR69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VR69-1", "url": "https://www.uniprot.org/uniprotkb/Q9VR69-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRQCLVGVLLVITGANGQGKEKEEFQCPSHIANGNYADPATCRRFYQCVDGYPYLNRCPSGLFFDDVQKFCTFKDEAKCGPLPTTPAPATEAPADTAQRCNTENCALPYCFCSKDGTQIPGDLEPEKIPQIIMLTFDGAVNLNNYQHYQKIFDGKRKNPNGCLIRGTFFMSHEYSNYQQIQHLGYYGHEIGTESISQQQGLQDKGYEEWVGEMIGMREILRHFANVSVNDVVGMRAPFLKPGRNTQYKVLEDFGYIYDSSITVPPVPVPVWPYTLDYKISHECKSGTCPSRTFPGVWEVPLNTHYVEGYEGGHCPYLDQCVLHNLDEEEVFQWLQEDFSRYYEQNKAPYMMPFHTNWFQTKPLENGLHKFLDWALELPDVYILTVTQMLQYVTDPKELRDVSQIESWKCDKSVSVAPKPCNIWQTCALPFKIPEQNLTDTRYMETCRECPNVYPWLGDAGGTGIAGRDNYIFAGGENPEEEDSAK", "length": 486, "header": "tr|Q9VR69-1|Q9VR69_DROME Isoform 1 of Chitin deacetylase-like 4 OS=Drosophila melanogaster OX=7227 GN=Cda4 PE=1 SV=2 CANONICAL=Q9VR69-1" }, "isoforms": [ { "isoform_ac": "Q9VR69-1", "url": "https://www.uniprot.org/uniprotkb/Q9VR69/entry#Q9VR69-1", "sequence": { "sequence": "MLRQCLVGVLLVITGANGQGKEKEEFQCPSHIANGNYADPATCRRFYQCVDGYPYLNRCPSGLFFDDVQKFCTFKDEAKCGPLPTTPAPATEAPADTAQRCNTENCALPYCFCSKDGTQIPGDLEPEKIPQIIMLTFDGAVNLNNYQHYQKIFDGKRKNPNGCLIRGTFFMSHEYSNYQQIQHLGYYGHEIGTESISQQQGLQDKGYEEWVGEMIGMREILRHFANVSVNDVVGMRAPFLKPGRNTQYKVLEDFGYIYDSSITVPPVPVPVWPYTLDYKISHECKSGTCPSRTFPGVWEVPLNTHYVEGYEGGHCPYLDQCVLHNLDEEEVFQWLQEDFSRYYEQNKAPYMMPFHTNWFQTKPLENGLHKFLDWALELPDVYILTVTQMLQYVTDPKELRDVSQIESWKCDKSVSVAPKPCNIWQTCALPFKIPEQNLTDTRYMETCRECPNVYPWLGDAGGTGIAGRDNYIFAGGENPEEEDSAK", "length": 486, "header": "tr|Q9VR69-1|Q9VR69_DROME Isoform 1 of Chitin deacetylase-like 4 OS=Drosophila melanogaster OX=7227 GN=Cda4 PE=1 SV=2 CANONICAL=Q9VR69-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "33925313", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33925313" }, { "id": "Q9VR69", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9VR69" } ], "filter_code": "00000000000000000000.0000000.00000001000000.1000000.0100000000.110100100001111011.10000.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_reported_with_glycan" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VR69", "url": "https://www.uniprot.org/uniprotkb/Q9VR69" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VR69", "url": "https://www.uniprot.org/uniprotkb/Q9VR69" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VR69", "url": "https://www.uniprot.org/uniprotkb/Q9VR69" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VR69", "url": "https://www.uniprot.org/uniprotkb/Q9VR69" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VR69", "url": "https://www.uniprot.org/uniprotkb/Q9VR69" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VR69", "url": "https://www.uniprot.org/uniprotkb/Q9VR69" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VR69", "url": "https://www.uniprot.org/uniprotkb/Q9VR69" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VR69", "url": "https://www.uniprot.org/uniprotkb/Q9VR69" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VR69", "url": "https://www.uniprot.org/uniprotkb/Q9VR69" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VR69", "url": "https://www.uniprot.org/uniprotkb/Q9VR69" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VR69", "url": "https://www.uniprot.org/uniprotkb/Q9VR69" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] }, { "title": "Drosophila O-GlcNAcase Mutants Reveal an Expanded Glycoproteome and Novel Growth and Longevity Phenotypes.", "journal": "Cells", "date": "2021", "authors": "Akan I, Halim A, Vakhrushev SY, Clausen H, Hanover JA", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9VR69", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9VR69" } ], "reference": [ { "type": "PubMed", "id": "33925313", "url": "https://glygen.org/publication/PubMed/33925313" } ] } ], "pathway": [ { "id": "dme:Dmel_CG32499", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG32499", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "Q9VR69", "url": "https://www.uniprot.org/uniprotkb/Q9VR69" } ], "pmid": "" }, { "name": "chitin 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"name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "Q9VR70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VR70/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_608475", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608475" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VR70", "url": "https://www.uniprot.org/uniprotkb/Q9VR70" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG12446", "url": "https://www.uniprot.org/uniprotkb/Q9VR70", "locus": { "chromosome": "X", "start_pos": 22809292, "end_pos": 22811935, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0031201", "url": "https://www.ensemblgenomes.org/id/FBgn0031201" } ] } } ], "crossref": [ { "id": "FB:FBgn0031201", "url": "https://alliancegenome.org/gene/FB:FBgn0031201", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0031201", "url": "https://bgee.org/?page=gene&gene_id=FBgn0031201", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0031201", "url": "https://flybase.org/reports/FBgn0031201", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "33147", "url": "https://www.ncbi.nlm.nih.gov/gene/33147", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VR70", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VR70*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR005240", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005240", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG12446", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG12446", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VSRCDTH", "url": "https://omabrowser.org/oma/group/VSRCDTH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VR70", "url": "https://www.orthodb.org/?gene=Q9VR70", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20992", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20992", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20992:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20992:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04087", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04087", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_608475", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608475", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VR70", "url": "https://www.uniprot.org/uniprotkb/Q9VR70", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VR70-1", "url": "https://www.uniprot.org/uniprotkb/Q9VR70-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCAAVCVMVTVPTEAEELKLCPKPLVGASYCSSCGGCVRSRCTEEPSGEVCERCWRLSQIAGSSVHRDAVPMANTLQYSTTSAPMSQGRALQLLNLKGDASLEKLLRAIAKELRLENVFWTHDISGRQVQARFDLLQDERYERLLCTLQDWGVGDRPGTHVSALTCLETRAKPCLQVPRQDHDNFVDQHQEHGEGQGQGQGQAQGQGWQSFMDSVRCRLNVNQVVRQVRRDATLTFDFVVLLIAAALLSCVGLVENSFLFLSSSMLISPLMGPIIAAIFGSVIGDRDLRWLGLKNELLGIAASVAIGFFFGAMVCGFGHFFAISKGLTEEIVSRCDTHSLAIGVCTALASGAAGAIAVLGGNTGSLVGVAISASLLPPAVNAGLLWALAVGVHVLPDDHEPLASMVKHRSYSSQLSVELLVCAAVSMALTLLNIICVWLMGTVVLRIKEVAPAVQRHQKFWHHDIRTAREVALDPVLQSAIDRLDKSQLDSDASPYQRAWSPGLDRQTASHTGIGSYDINLSCSKDQPNNYHTVHGFQEFCITLHRLKSAHKVAPPPTIMELFTRAPPNSDQTNIGGSDFSSCRSLPDISSHSRLWPHKPPSAMSIQGLIFGAAKSGEPGPAVPMATSSNREREKMNVHWREEELQEDLVLRREILNSRESSPLRRPGQVLIPLPRLEGNFLMNRPLSLLPYGRSEGASPGEKQDEFQA", "length": 709, "header": "tr|Q9VR70-1|Q9VR70_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG12446 PE=4 SV=1 CANONICAL=Q9VR70-1" }, "isoforms": [ { "isoform_ac": "Q9VR70-1", "url": "https://www.uniprot.org/uniprotkb/Q9VR70/entry#Q9VR70-1", "sequence": { "sequence": "MCAAVCVMVTVPTEAEELKLCPKPLVGASYCSSCGGCVRSRCTEEPSGEVCERCWRLSQIAGSSVHRDAVPMANTLQYSTTSAPMSQGRALQLLNLKGDASLEKLLRAIAKELRLENVFWTHDISGRQVQARFDLLQDERYERLLCTLQDWGVGDRPGTHVSALTCLETRAKPCLQVPRQDHDNFVDQHQEHGEGQGQGQGQAQGQGWQSFMDSVRCRLNVNQVVRQVRRDATLTFDFVVLLIAAALLSCVGLVENSFLFLSSSMLISPLMGPIIAAIFGSVIGDRDLRWLGLKNELLGIAASVAIGFFFGAMVCGFGHFFAISKGLTEEIVSRCDTHSLAIGVCTALASGAAGAIAVLGGNTGSLVGVAISASLLPPAVNAGLLWALAVGVHVLPDDHEPLASMVKHRSYSSQLSVELLVCAAVSMALTLLNIICVWLMGTVVLRIKEVAPAVQRHQKFWHHDIRTAREVALDPVLQSAIDRLDKSQLDSDASPYQRAWSPGLDRQTASHTGIGSYDINLSCSKDQPNNYHTVHGFQEFCITLHRLKSAHKVAPPPTIMELFTRAPPNSDQTNIGGSDFSSCRSLPDISSHSRLWPHKPPSAMSIQGLIFGAAKSGEPGPAVPMATSSNREREKMNVHWREEELQEDLVLRREILNSRESSPLRRPGQVLIPLPRLEGNFLMNRPLSLLPYGRSEGASPGEKQDEFQA", "length": 709, "header": "tr|Q9VR70-1|Q9VR70_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG12446 PE=4 SV=1 CANONICAL=Q9VR70-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VR70", "url": "https://www.uniprot.org/uniprotkb/Q9VR70" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VR70", "url": "https://www.uniprot.org/uniprotkb/Q9VR70" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VR70", "url": "https://www.uniprot.org/uniprotkb/Q9VR70" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VR70", "url": "https://www.uniprot.org/uniprotkb/Q9VR70" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VR70", "url": "https://www.uniprot.org/uniprotkb/Q9VR70" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. 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Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VR79", "url": "https://www.uniprot.org/uniprotkb/Q9VR79" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VR79", "url": "https://www.uniprot.org/uniprotkb/Q9VR79" } ], "reference": [ { "type": "PubMed", 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Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VR79", "url": "https://www.uniprot.org/uniprotkb/Q9VR79" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VR79", "url": "https://www.uniprot.org/uniprotkb/Q9VR79" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VR79", "url": "https://www.uniprot.org/uniprotkb/Q9VR79" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VR79", "url": "https://www.uniprot.org/uniprotkb/Q9VR79" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VRA5", "url": "https://www.uniprot.org/uniprotkb/Q9VRA5" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VRA5", "url": "https://www.uniprot.org/uniprotkb/Q9VRA5" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VRA5", "url": "https://www.uniprot.org/uniprotkb/Q9VRA5" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VRA5", "url": "https://www.uniprot.org/uniprotkb/Q9VRA5" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VRA5", "url": "https://www.uniprot.org/uniprotkb/Q9VRA5" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VRA5", "url": "https://www.uniprot.org/uniprotkb/Q9VRA5" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VRA5", "url": "https://www.uniprot.org/uniprotkb/Q9VRA5" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VRA5", "url": "https://www.uniprot.org/uniprotkb/Q9VRA5" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG15461", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG15461", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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194190.0 }, "refseq": { "ac": "NP_001259763", "name": "uncharacterized protein, isoform C", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259763" }, "gene_names": [ { "name": "Dmel\\CG1494", "type": "recommended", "evidence": [ { "id": "Q9VRG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VRG3" } ] }, { "name": "CG1494", "type": "synonym", "evidence": [ { "id": "NP_001259763", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259763" }, { "id": "Q9VRG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VRG3" } ] }, { "name": "DmCG1494", "type": "synonym", "evidence": [ { "id": "NP_001259763", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259763" }, { "id": "Q9VRG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VRG3" } ] }, { "name": "Dmel\\CG1494", "type": "synonym", "evidence": [ { "id": "NP_001259763", "database": "RefSeq", "url": 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"evidence": [ { "database": "UniProtKB", "id": "Q9VRG3", "url": "https://www.uniprot.org/uniprotkb/Q9VRG3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG1494", "url": "https://www.uniprot.org/uniprotkb/Q9VRG3", "locus": { "chromosome": "X", "start_pos": 21292458, "end_pos": 21285301, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0031169", "url": "https://www.ensemblgenomes.org/id/FBgn0031169" } ] } } ], "crossref": [ { "id": "FB:FBgn0031169", "url": "https://alliancegenome.org/gene/FB:FBgn0031169", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0031169", "url": "https://bgee.org/?page=gene&gene_id=FBgn0031169", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03263", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03263", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0031169", "url": "https://flybase.org/reports/FBgn0031169", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "33102", "url": "https://www.ncbi.nlm.nih.gov/gene/33102", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VRG3", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VRG3*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR003439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013525", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013525", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026082", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026082", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG1494", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG1494", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KYEDQFP", "url": "https://omabrowser.org/oma/group/KYEDQFP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VRG3", "url": "https://www.orthodb.org/?gene=Q9VRG3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19229", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19229", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19229:SF250", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19229:SF250", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00005", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00005", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12698", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12698", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-1369062", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1369062", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001259763", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259763", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VRG3", "url": "https://www.uniprot.org/uniprotkb/Q9VRG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VRG3-1", "url": "https://www.uniprot.org/uniprotkb/Q9VRG3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTVRSYIRKFLLMNWKNHKLQLANPLELLVILLVPPLFTLVAVLMRFFIPVNHRSDTVYDPIDLDRSWMQMVEKLEKARQVADTYNVKGNPFTPHLVIGWAPKRYGIFQAMMRRVQKQIEPMTSVGFEDCEEMRESVIENGLFAGLCFDGSPFVEDQVFEEDTLESYSNIQPMLNYTILLPSELRMLDGDFRMANWMTLYNDDPNTFVLTRLNQPYEGGFVGYVREGFIRLQKSVSESFLVLTSHKSLPTIQIRRFPITGREQDPLMGNLNYGMPFIIIIGFLFPAQLFVWQVVSEKQSQVRQFLINMNIGNLIHFVSWYLKGLIYEMISSLIIAALLKIRWDQDHGVLTQTPWYILILVLFCYNCAAVAFAIMVAAFFRNALNAVRVLTILWIMSYVPTFILSNNLEGNIHALRYVSYALPNVVATLVIEFLIERESIVHITWEDSGYRLNYDGGHITVTASSWIFMLNALVYCAIGLYVDMWRGGDRSGKKMKKPNTNASVQEDPYHERGDSFTHQGQAIGVNSTKIYEVEPSHRRFKLKIKKLCKRFATNDRPALNLFSWNVYENEVTVLMGHNGCGKSTLLKILAGLVEPSRGTVMISSHNIQTERKAASMELGIAFGHDMLLTGFTVIDYLRFICRVKGLHNNIEIDGQSNYFLNVLQIGGLKTKRIRTLTDRDLCLVSICCAFVGNSPIILIDDVHSDLDKRTQSLVWNLINEEKSKRTIILVSNSPALAENIADRMAIMSNGELKCTGTKPFLKNMYGHGYRLTCVKGKNYKRDELFGMMNSYMPNMSIERDIGYKVTFVLENKFEDQFPMLIDDLEENMQQLGVVSFRIRDTSMEEIFLRFGCEDNDQSGAFQSHENAQVLLEEYYSTLAEANEKGRRTGWKLFFLHGRAVIYKRWIAAHRHWIVLIFEVLAMALVAVCTFSSIFIYGKNYELEPLTFNLSQLHTVDAFVELFSEEEDVKDMHAYYTELLYWYDAHVATLTKNRHNAYALLTQNQFTAHVNSRYIFGATFDQKIVTAWFNNIPLHSAPYALNVVHNAVARHLFDEEATIDVTLAPLPFRTAINTFPPSSHTFGGCLAFGICFVLTFIWPAFAIYMITERGSLLKKQQFLAGVRVCSYWTFTVLYDLLFLLIFCACVVVMVALYENPNHDVMLYGYISVTLMLGGFWVILLAYLMASLCRNPCYGFLWLCGINSIGLVCFSQFYRTHPESMLLEPTFMAMYTVATVICKLFMIYEFKLICMDPVVNFTSVEVFKCNSIPNCCIKSNYGTFTAGIYHDLVILTLLDIILLACLFVSEYHSILGFADCRLDTRTNESPDSNQESRAFPGILSNDTAALVDKEHTSRLNEEERSKYAAVGIGIVSKYRRNRVLRDLDFTLAKSECLSITGANNSGKTTLLKVVVNETKMNAGQLWIHDYSVNTHRVQCYRMVGYCPQKDSLPSEFTPRELLYIHAMLQGHRHRIGRELSEALLRLVGLTPCWNRSVRMCTTGQIRRLYFAYAVLGSPDLICVDGVPAGLDPTGKRIILMMTSTMQAMGSSFLYTMLTGLDAERLSLRTPLLLEGQLWMIRPMDTETENYKSGYQLEVRFKRKVNPNVSMSRATWNLINHFPMSPNKKFSAFMEIKFPDAVLTIERDDSMVFVLPLGTTTFSEIFLTLRKDAFEMNIEDYFITRNMLVGFQIFTYDQHQDNP", "length": 1695, "header": "tr|Q9VRG3-1|Q9VRG3_DROME Isoform 1 of ABC transporter domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG1494 PE=4 SV=3 CANONICAL=Q9VRG3-1" }, "isoforms": [ { "isoform_ac": "Q9VRG3-1", "url": "https://www.uniprot.org/uniprotkb/Q9VRG3/entry#Q9VRG3-1", "sequence": { "sequence": "MTVRSYIRKFLLMNWKNHKLQLANPLELLVILLVPPLFTLVAVLMRFFIPVNHRSDTVYDPIDLDRSWMQMVEKLEKARQVADTYNVKGNPFTPHLVIGWAPKRYGIFQAMMRRVQKQIEPMTSVGFEDCEEMRESVIENGLFAGLCFDGSPFVEDQVFEEDTLESYSNIQPMLNYTILLPSELRMLDGDFRMANWMTLYNDDPNTFVLTRLNQPYEGGFVGYVREGFIRLQKSVSESFLVLTSHKSLPTIQIRRFPITGREQDPLMGNLNYGMPFIIIIGFLFPAQLFVWQVVSEKQSQVRQFLINMNIGNLIHFVSWYLKGLIYEMISSLIIAALLKIRWDQDHGVLTQTPWYILILVLFCYNCAAVAFAIMVAAFFRNALNAVRVLTILWIMSYVPTFILSNNLEGNIHALRYVSYALPNVVATLVIEFLIERESIVHITWEDSGYRLNYDGGHITVTASSWIFMLNALVYCAIGLYVDMWRGGDRSGKKMKKPNTNASVQEDPYHERGDSFTHQGQAIGVNSTKIYEVEPSHRRFKLKIKKLCKRFATNDRPALNLFSWNVYENEVTVLMGHNGCGKSTLLKILAGLVEPSRGTVMISSHNIQTERKAASMELGIAFGHDMLLTGFTVIDYLRFICRVKGLHNNIEIDGQSNYFLNVLQIGGLKTKRIRTLTDRDLCLVSICCAFVGNSPIILIDDVHSDLDKRTQSLVWNLINEEKSKRTIILVSNSPALAENIADRMAIMSNGELKCTGTKPFLKNMYGHGYRLTCVKGKNYKRDELFGMMNSYMPNMSIERDIGYKVTFVLENKFEDQFPMLIDDLEENMQQLGVVSFRIRDTSMEEIFLRFGCEDNDQSGAFQSHENAQVLLEEYYSTLAEANEKGRRTGWKLFFLHGRAVIYKRWIAAHRHWIVLIFEVLAMALVAVCTFSSIFIYGKNYELEPLTFNLSQLHTVDAFVELFSEEEDVKDMHAYYTELLYWYDAHVATLTKNRHNAYALLTQNQFTAHVNSRYIFGATFDQKIVTAWFNNIPLHSAPYALNVVHNAVARHLFDEEATIDVTLAPLPFRTAINTFPPSSHTFGGCLAFGICFVLTFIWPAFAIYMITERGSLLKKQQFLAGVRVCSYWTFTVLYDLLFLLIFCACVVVMVALYENPNHDVMLYGYISVTLMLGGFWVILLAYLMASLCRNPCYGFLWLCGINSIGLVCFSQFYRTHPESMLLEPTFMAMYTVATVICKLFMIYEFKLICMDPVVNFTSVEVFKCNSIPNCCIKSNYGTFTAGIYHDLVILTLLDIILLACLFVSEYHSILGFADCRLDTRTNESPDSNQESRAFPGILSNDTAALVDKEHTSRLNEEERSKYAAVGIGIVSKYRRNRVLRDLDFTLAKSECLSITGANNSGKTTLLKVVVNETKMNAGQLWIHDYSVNTHRVQCYRMVGYCPQKDSLPSEFTPRELLYIHAMLQGHRHRIGRELSEALLRLVGLTPCWNRSVRMCTTGQIRRLYFAYAVLGSPDLICVDGVPAGLDPTGKRIILMMTSTMQAMGSSFLYTMLTGLDAERLSLRTPLLLEGQLWMIRPMDTETENYKSGYQLEVRFKRKVNPNVSMSRATWNLINHFPMSPNKKFSAFMEIKFPDAVLTIERDDSMVFVLPLGTTTFSEIFLTLRKDAFEMNIEDYFITRNMLVGFQIFTYDQHQDNP", "length": 1695, "header": "tr|Q9VRG3-1|Q9VRG3_DROME Isoform 1 of ABC transporter domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG1494 PE=4 SV=3 CANONICAL=Q9VRG3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VRG3", "url": "https://www.uniprot.org/uniprotkb/Q9VRG3" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VRG3", "url": "https://www.uniprot.org/uniprotkb/Q9VRG3" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VRG3", "url": "https://www.uniprot.org/uniprotkb/Q9VRG3" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VRG3", "url": "https://www.uniprot.org/uniprotkb/Q9VRG3" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VRG3", "url": "https://www.uniprot.org/uniprotkb/Q9VRG3" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VRG3", "url": "https://www.uniprot.org/uniprotkb/Q9VRG3" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VRG3", "url": "https://www.uniprot.org/uniprotkb/Q9VRG3" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VRG3", "url": "https://www.uniprot.org/uniprotkb/Q9VRG3" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VRG3", "url": "https://www.uniprot.org/uniprotkb/Q9VRG3" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VRG3", "url": "https://www.uniprot.org/uniprotkb/Q9VRG3" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VRG3", "url": "https://www.uniprot.org/uniprotkb/Q9VRG3" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG1494", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG1494", "resource": "KEGG Pathway" }, { "id": "R-DME-1369062", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1369062", "resource": "Reactome", "description": "ABC transporters in lipid homeostasis" }, { "id": "R-DME-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M9Q293-1", "protein_name": "Phospholipid-transporting ATPase ABCA3", "gene_name": "abca3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAVWQQFGLLLWKNYIQQKRQILVTLVEIALPLLFSAILIVLRQKVSFTNYPNATHYQSFPLNGLPPLLCYQQLQLAYVPANASVVQQIAQDVQQNLQSCIKNVRGFETEEQFEEFVKTDPESGKILAAIVFEHPFSHDDEPLPLQVSYHLRFTYSPRNAPAREKSELNPNNDMDWHTLSLFPLFQMPGPREQHDPHGGTPGYYREGFLQVQYAVDRAIMMAYNRSAAMALFDQTQVLLSRFPYPAFIYDVFILAIQNQLPLLLVLSFTYTALNIVRAVVQEKERKLKEYMRMMGLSNWLHWSAWFLMFFLFLSISIFFVTVLFCVKVSPNGAVLTYSDPTLVFVFLLVFAISTINFSFMISVFFSRANVAAAAGGFIYFLSYLPYVFLWPRYDLLSHAQKVSACLISNVAMAMGAQLIGMFEGKGTGIQWHNLFEAVTVDDDFSLAQVIGLLLLDALLYGLVAWYVEAVFPGEYGVPQPWYFFILPSYWCSSPRVAFLKEKEDEEDAEKASKGEFMEEEPAGLVAGVKIKRLAKVFKVGNKSKEAVRDLTLNMFEGQITVLLGHNGAGKTTTLSMLTGLFPPSSGRAYINGYDICQDMALIRRSLGLCPQHDVLFDNLTVREHLLFYTQLKGYPREKIPGEVDRIIRILNLEDKRNAKCKTLSGGMKRKLSIGIALIGDSKVVMLDEPTSGMDPSARRATWDLLQGEKRGRTILLTTHFMDEADLLGDRIAIMASGELQCCGSPLFLKNKYGAGYHMVIVKDAFCNVSEITRLVHMYVPDATLESSAGAELSYILPKESTSRFELLFAELEMNRDELGIASYGASVTTMEEVFLRVGKLVDSSLDIQAIQLPALQYQHERRSHDWTMDDSSSISGMTDVTDFTDSCTMISEDGSNIKLNTGARLYMQQFYAMFLKRALYSWRNWKVMVAQFLVPLIFTVLALVVARSLPSSHSSPQLRLALKQYGQTHVPVAVEANAGPLASLLAEIYTTQLPSQNAIAAPNITDFSEYVLYNAQREGGAFNEHCVVGAAFRSSDVIGYFNNQGYHTPATALMLVDNALFKLLAGPNASIQTGNDPMPRNVSETAQSQLSESQTGFAIAINLMYGMASLASTFALLLVSERSVKSKHVQQVSGVYLTNFWFSALLWDLINFLLPCLLMLVVFRVFSVKAFVAQNHLVDVLFLLLLYGWAVIPLMYLMSFLFSTAATAYTRLTIFNIISGTATFLAVTIMTIPELNLLHLSHLLDKVFLIFPNYCLGMSFTEFYQNYEMITFCTSSPLAKYICKYYNITYQMNYFSMEEPGVGRFLVALSLQGVVFIILLFLIELRCIRLLLNLCRRRKKALLLAEEALQPEDRDVAEERKRVLECQPVVESMVGSPLVVQELSKMYSGGQSLLAVDRLSLAVGKGECFGLLGFNGAGKTTTFKMLTGDESITSGDAFIDGYSILTDVKKVQQRIGYCPQFDAVLDHMTGRETLSMYARLRGIPEKYVTACVENVLRSLLLEPHADKLVRSYSGGNKRKLSAGMALIGGPPVIFLDEPSTGMDPVARRLLWDAITRTRESGKAIIITSHSMEECEALCTRLAVMVNGQFKCLGSPQHLKSKFGSGYTLLAKVRVETELEESDLQLFKDFIESTFPGSLLKDEHQGMVHYHLTDKTLTWAQVFGVLETAKEKYSIEDYCVSQISLEQVFLSFAQFQHCAEACRK", "length": 1703 }, "evidence": [ { "id": "MGI:2388709", "url": "https://alliancegenome.org/gene/MGI:2388709#orthology", "database": "AGR" }, { "id": "MGI:3625331", "url": "https://alliancegenome.org/gene/MGI:3625331#orthology", "database": "AGR" }, { "id": "RGD:1305981", "url": "https://alliancegenome.org/gene/RGD:1305981#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A1ZBS3-1", "protein_name": "ABC transporter domain-containing protein", "gene_name": "Dmel\\CG8908", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSSGESPVKTQSSICLLWLVICKTARFQFSNTLTSVIIIVGPIVVFLVYAATALFREPQEETSVKYPPVNITTKVPYIYYSPENLVLAAVIEDVVHDLKAVGSKAFASASELNKALIGKDTYGYVGIEFDDSFSDINELPINVTVGLRFPLHLRKNPKMVWDNTSILKHSKMDVDYYQVEGFLVVQAKLSEALIRAKNEAVVLPEVILQHYPDVAEVDRLDNRVALGGVLFLPVTISAAYLAQMIVMERRDHLRDMLELMGVRAWIYWLSWFLVAFLLLSIPTVFMVLLLKWRYFSLSDSSLVLFFLLVYNLEVLTSAFMISSFFSDTVGVQVAIVIVHLIGCLPWRLLLMGYVPTLPRTIFVCLFLNSSLAMGLQQFIKSENLRLGLHWTYLFERTDWDEFVHLGPILLFMLFGCLLRILVLAYMEQLRSYQNRKWYFPVQPSFWCRWNRRPRSDDFDVEGQETGIRGHPLIVRARNIEKVFNEWIAVKDLNLNFYQDEITVFLGHNDSGKSTILMLLAGFLRPSAGEITINGYDLATNQRKARQSMCICPQPNVLFEKVNARWHLQFYCRLKGLNRQEASAETDKYLEIGRLQDFANTKVKNLPSGIKRMLMLCCNLCGNSKILLLDEPGTSMDPAMRSNMWDLLRRERKGRCIIMATHNMNEAEVVADQIVVLCDAQVIGYGTTGFLTQIAGTGSSYLLICTKMDTCIVAEVTNFLQIRFPDIKLHNEFSIYVTYELPTKYVQQYAALFLELEEALGELNLAEISVCAPTLGSVFLQMGEEMRQSWNRISSFDLLSSPSPMLSLLNLLPTFEVREDDGRVKCCNQWRAIVEKKRLFTLRHQKFYCMIIATPIIICLLIISFSIFIFLVDHHLSELLVTDLSIYPKAVFVIDSPAEGNRFERHYMANVIGQGGTVRSTSGTPIDDYLLAEMESDQVKVQHTFLAGATFDSNANSIIAWSNNKLKHGSALSMGLVYAAIGQELAKLDIRIVNKPYQDTVQQAVRGLIYASTIEFAVLVFHYLVLGTAIFAVLPIVERRSKVQHQQFSSGMSRSTYWLSHLSWDYCFYIAMILPLIVVAGITIGSVLPVIVQLLAFGFSAISFTYLLCLMSNDFGKMFSIILYINMIGVLALFIHPKSPQTRYAVIESVLLVHPHYSLCCGMYEAIRMSTFSLKQLPYLIFSGAAYLTIVVFAWVPRRLNYVFKSIRNEKIYPSYKDEDKEVDKMRRRLAYLTTAHYAFFPLILKNLSKRYGSFVAVRSLTLDLNPFECVGLLGRNGSGKSSIFRMIVGMESITVGSIHIKGYSLKTRPKDASRHVGFCPRELMLLSFMTGKDALRFCCLINGIRREYIKSLVASLAECFELVPHMNKRISTYSNGTKRKLMIAMGTLAPSLMCLDEPTAGVDMHAKYEIWSILDGIRQGGRSILLTTHNLEECEFLCTNVGIMDHGSLLCYGSLSRLKHRFNMGIFVKVKMGTRAEMDDERDNWMQITMMPPNDSEMGSTVGARRMMLAHLLRHHNPPVEPVKKSRTSRAQPDTTNSELNMRKDYEALLQELEEVFKKDHPYSTVSEKYSYRGMITFCIPRGQIKWSAIFEYMENLKDEMQILYYSVSHTTFQDVFMKFVRKQNQ", "length": 1626 }, "evidence": [ { "id": "MGI:2388709", "url": "https://alliancegenome.org/gene/MGI:2388709#orthology", "database": "AGR" }, { "id": "MGI:2388708", "url": "https://alliancegenome.org/gene/MGI:2388708#orthology", "database": "AGR" }, { "id": "MGI:2388711", "url": "https://alliancegenome.org/gene/MGI:2388711#orthology", "database": "AGR" }, { "id": "MGI:3625331", "url": "https://alliancegenome.org/gene/MGI:3625331#orthology", "database": "AGR" }, { "id": "RGD:1561491", "url": "https://alliancegenome.org/gene/RGD:1561491#orthology", "database": "AGR" }, { "id": "RGD:1305981", "url": "https://alliancegenome.org/gene/RGD:1305981#orthology", "database": "AGR" }, { "id": "RGD:1560494", "url": "https://alliancegenome.org/gene/RGD:1560494#orthology", "database": "AGR" }, { "id": "RGD:1563534", "url": "https://alliancegenome.org/gene/RGD:1563534#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "D3ZQI3-1", "protein_name": "ATP-binding cassette, subfamily A (ABC1), member 16", "gene_name": "Abca16", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNQLLLNQLTVLLWKNFTLKKRQVLSTVMEVLAALLFVIMLLIFRALTDMNIAGPYHFTPQPIATMPSFIKDAQEWELIYIPSEIDVVTEIIEDVKRNLNITIKVRGFPSEVEFEEYILFDYTSQKVLAAIVFDCDFKNKTDPLPLQVKYHLRFVGAQRTIWWPDKIGWKTRLLFPNHPSLKPRNPNYLDGGSPGYIKEGFLAVQHAVDKSIMLYHESRAGKELFENIDTLVQRFPYPSHPQDKLLWISSPFIPLMFILMFSSIVLSIMRSIVFEKEKRLKEYQLIMGLRNWIIWMGYFFTFFPLYVAIIFLICILLFIQIVEEPILRYSDCSFIFVFLTCYAIASICFAFMVSTFFSKTRLAASAGNLLFFASFFPYNFISEYYGMLDLTTKITACLSANVALALGINILIKLEIQEIGVKWDNLWTPANLEDNLNFGYMLGMLLLDAFLYSLVTWYVEAVFPGQCGVPQPWYFFIMRSYWFGKPKIRKIGEEAKSIPVVHNCYEAEPSNLEAGIQIKHLHKEFKTKPAINNLSLNIYEGQVTVLLGHNGAGKTTTLSVLTGRFAATRGEAYINGYNISDNMAEIRKDLGFCPQHDLLFDDLTLSEHLFFYCMIKGHPQNINCVEINRMLSVFNLQENYHTLSGSVSGGVRRKLSIILALMGGSKVVILDEPSSGMDPMSRRATWDILQHYKQNRTILLTTHYMDEADVLGDRIAIMVRGTLHCCGSSVFLKQIYGAGYHIVLEKEPYCDVDNIIAMIQQHVPGSMLENDIGNELSFILPKKYVSRFETLFTELEMRQKALGIANFGASITTMEEVFLKVNKLAAPQRSIQTIQPYYLTYKKMRQDEQQNVNILRNYNKPIFPYLREIATVKFNTGVPLYRQQFYSMFIKRALFIGRNWKLMFLQIIVVLVVTTYLLLSLHLDDNDIPERELNLSHYGKTIVPYSISGNSDLALNLIKNLKIFLKSKNQSLKKIKGDMNNYILENKDCRTFCIIALSIKVERNKTVLTIFFNNEAYHSPAISLSILDNILFMTLSGRDASITAFNKPQPLPHYGSNTVPVNGLQIVQCLAFGISVVVGSFSIQTVTERISQAKHIQFLTGVCVLTYWLSALLCDLIFFFFACCVLLGIFRFCQLEAFVVHYNFLDTILIFMLYGWCVVPLTYLGSFLFNSSTAAYIKITLFNYFSTMFSIIIYTIVQFYGEDFPALIHILIKTILMALPSYNLAMSISKYFDDYEVKRLCAREFRSIYMDCSEPFIQNNVYGFGEHGIGKFLITLATMGLVFLLLLLSLESVSSSLKNFVFRNVLFYFYNKIRKGRHGVHSKSTKEDEDEDIRKEKRKVFTLLLRLQNTPLVLNEVTKIYFKCPVVKAVKNISLVVRKSECFGLLGLNGAGKTTTFKMLTGEETITSGIAFIDGNSVTKNPRKIRSRIGYCPQSESVLNHMTGRESLIMYARLWGVPEQDINEYVEAFLHSVHLEPIADQIIYTYSAGSKRRLSTAIALMGKSSVVFLDEPSTGMDPVAQHLLWDTVTWVCKTGKAIIITSHRMEECEALCSRLAIMVKGKFTCLGTPQHVRKRFGQVYTLTVKINIAKDEEKVKEFKDFIKSTFPGNIKFQEFHGTIGYYIPSTEICWGKVFEILEEAKVLFKLEDYSVKQVTLEQIFLTFANTDKMKTYREIKLQEA", "length": 1680 }, "evidence": [ { "id": "MGI:2388711", "url": "https://alliancegenome.org/gene/MGI:2388711#orthology", "database": "AGR" }, { "id": "RGD:1563534", "url": "https://alliancegenome.org/gene/RGD:1563534#orthology", "database": "AGR" }, { "id": "FB:FBgn0031169", "url": "https://alliancegenome.org/gene/FB:FBgn0031169#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ACN5-1", "protein_name": "ATP-binding cassette, subfamily A (ABC1), member 15", "gene_name": "Abca15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASPASKKLLLLLWKNFTLKRRKFGALVTEIILMLAFSIVLLTTRHLLSINKMESLHFPDQPVGAVPFFFRVSANSSRPWELAYVPSNITVVHNIVENVKKDLNFPMAVIGFPSESDFEDYARSSVNSRNILAAIVFDHNFANSRDPLPKKIKYNLRFSDIKKNIHGMAYYQGHTWLTKFLFPPLRIVGPRNPQEADGGSPGYITEGFLAVQHALDKAIMLHHGGAAATALFNDVSLFIQRFPYPAYYHDHFYLFANTFVPLTVASIFFLNHLILVWSIVWEKENRLKEYQLMIGLRNWMFWIAYFFTFFCLYFINIIFMCIVLFVKIDPAPIFQYNDPILVFILLLFYAISSIFFSFMISTLFNRVSFAVSLGSFLFFLTYLPAITMNQSFEHMPPRQKLIWSFDFNVGMAFGFRFLVNAETRKTGMKWNNIFLPTDSDSLLFTYVLGMLLVDAFIYGLVAWYIEAVFPGEYGVPKPWNFFLMHSYWFGESRQQKPEITQFCKRVESKYFEVEPTDLTAGIQIKHLHKVFQENNITKVAINDLSLNVYEGQITVLLGHNGAGKSTTLSILSGLYPPTSGEAYVHGEDISQHMDQIRNFLGLCPQQNLLFDHLTVSEHLYFYCRVKGVPQNMCLEETNNMLSAFNLTEKRDAFSKSLSGGMKRKLAIIIALIGGSKVVILDEPTSGMDPASRRSTWDVVQTYKQNRTILLTTHYMDEADMLGDRIAIMVQGTLRCCGSSVFLKRLYGVGSHIVMVKEPVCDVDEISKLIHYYIPTATLKTNVGNELSFILPKEYTHKFEALLTALEENQENLGISSFGMSITTMEEVFLRVSKMEDSKPDMEATQSPSAGSKGNRNRDVESSMRAGFPTQSEDQTIVFNTGCPLYLQQFHAMFMKRLMYNWRNWRVLSVQILGLVISTFLLLKSHEFRHKRIRQMNLDDYGQTIVPFSILGKSNLTTSLLIHLENMLKPGNHQLKEVQGDLLKYLEGNEECIHLCIVALSIKVAAGRAKLTVLFNNEAYHSPSLSLAVLDNILFMSLSGANASITVFHKPQPRPTSKEWPRSTYGKIVAFKIQLGMALLVSGFCILTVTERITKAKHMQFLSGASVLVYWLSALVFDFIIFFISCCFLLVMFKYYKIDIYVTDYHILETMLILILFGWSAIPLTYLMSFLFSKSIPAYIQLLVFYYLSGTSGLLIDTIIEAGLSTIISNSTQTFLLSSLLFFPTYNLGKCISEYTVIYQRKILCIQQKNVLKYLNCSKEYTKKNIYSLKKPMIGKYLIAMSIAGFVYLLFIFFWENISWKLRMLIHQHIYFGVCKKYKSDIISNELSGTSEDNDVENERREILYQPEKFLNCPVLIKQLTKIYFKSPLILAVKNISLAIQERECFGLLGFNGAGKTTTFQILTGEITPTAGDVFIDGISITKDVLKVRSKIGYCPQFDALLEYLTGWEIMVMYARIWGISERQIRPYVNTYLNSLELEPHANSLISTYSEGNKRRLSTAIAMMGKPSVIFLDEPSTGMDPRARRLLWDAVIKIRESGKAIIITSHSMEECEALCTRLSIMVHGKLTCLGSPQYLKNKFGDIYILKTKVKSGETLKEFKNFITLTFPGSELKQENQGILNYYIPSKDNSWGKVFGILEKAKEQYDLEDYSISQITLDQVFLAFADQDRK", "length": 1668 }, "evidence": [ { "id": "MGI:2388709", "url": "https://alliancegenome.org/gene/MGI:2388709#orthology", "database": "AGR" }, { "id": "RGD:1305981", "url": "https://alliancegenome.org/gene/RGD:1305981#orthology", "database": "AGR" }, { "id": "FB:FBgn0031169", "url": "https://alliancegenome.org/gene/FB:FBgn0031169#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9PU17-1", "protein_name": "ATP-binding cassette sub-family A member 17", "gene_name": "Abca17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPFKKLKLLLWKNFVLKKRKTLVTVLETLMPVLFSAIVLYLRLNSMPRNKANTNYPAVDVSLLPVYFHNYPLKSKFQLVYIPSKSETLKAVTEVVEQTFAVDFEVLGFPSVSLFENYIIKDPKSFYVLVGIVFHHDFNSSNEPLPLVVKYDLRFSYVQRNSISPPRHLFFQEDIEGWCTAFLYPPNLSQAPREFSYADGGHPGYNKEGFLAIQHAVDKAIMLHHAPKAALDMFKNLQVSVQRFPSGSHIQDPFLVILQNEFPLLLMLSFICVELIITNSILLEKERKQKEYMYLMGLENWLHWVAWFITFFLSALVTVSGMTVLFCTKMNGVAVFRNSNTTLIFIFLMCFAIATIFFAFMMSTFFQRAHVGTVIGGIVFFFTYLPYMYITFSYHQRTYSQKILSCLFSNVAMAMGVRFISLFEAEGTGIQWRNMGSVWGDFSFTQVLVMLLLDSFLYCLVAFLVESLFPRKIGMPKSWYIFAKCPLWRKKSFPVIPPLLVIGDPEKTSKGDFLQDEPAGHINAIEIQHLYKVFYTGRSKCIAVKDLSMNLYKGQITVLLGHNGAGKTTVCSVLTGLIPPSKGHAYIHGCEISKDMVRIRKNVGWCPQHDILFDNFTVTDHLYFYGQLKGLSHQDCHEKIEEMLHTLGLEDKRNSRSKFLSGGIKRKLAIGIALIAGSKVLILDEPTSGMDSSSRRAIWDLLQQQKGDRTVLLTTHFMDEADLLGDRIAILAKGELQCCGTPSFLKQKYGAGYYMTIIKTPLCDTEKLAKVIYHHIPNAILESRIGEEMIFTLPKKAMPRFEALFADLEQRQTELGISTFGASVTTMEEVFIRVCKLADPSTNVLTEKRPSLRHLPRNHRVPVDRIKCLHSRIFSLSSDQPIRLNTGFSLLCQQFYAMLLKKVAFSRRNWMLVLSVQILLPLVIIMLSLSFFNFKLRKLDNVPLELTLQTYGQTIVPFFIAENSRLDPQLSDNFVKMLVAAGQVPLRIQGSVENFLLKKAKEAPEDFDKLYVVAASFEDVNDHTTVKALFNNQAYHSPSLALALVDNVLFKLLSGANASITTTNYPQPQTAMELSETILYQGPKGHYLVVNFLFGIAFLSSSFSILTVGEKSIKSKNLQFLSGVSMAAFWLSALLWDLISFLVPTLLLVLVFFWYKEEAFAHPQSIPAVVLIMMLYGWAIIPLVYTVSFSFKTPGSGCVKLVAMLTFLSISPVVLVTVTSEKDLGYTELSDTLDHIFLIFPGHCLGMAFSNLYYNFEIKKFCNAKNLSDIDCNDVLEGYVVQKNIYAWESLGIGKYLTALAILGPVYITLLFLTEANAFCALKARLSGFFCKQKLRMLLNVTGAEDEDVLEEAENIKYHLDTLIKKSPLVVKELSKVYKEKVPLLAVNKVSFVVKEKECFGLLGLNGAGKTSIFNMLTREQPITSGDAFVKGFNIRTDMAKVQQWIGYCPEFDALLNFMTGREMLVMHARIRGIPECHIKTCVDMILENLLMCVYADKLVKTYSDGNKRVLSTAIALLGEPTVILLDEPSTGMDPVARRLVWDAVGRVRESGKTIVITSHSMEECEALCTRLAIMVQGQFKCLGSPQHLKSRFGSGYSLQAKVRRKWQQQMLEEFKAFVDLTFPGSSLEDEHQSMVQYYLPGQNLSWAKVFGIMEQAKKDYVLEDYSISQLSLEDIFLSFTRPVPDTKENIQQGQAALDSSLSPSNSRPISSPPSSPPSSPPSSPPSRPPSRPSQPPSRPPSRHPSSPSQPPSRPPSRHPSSPSQPPSEPVLL", "length": 1773 }, "evidence": [ { "id": "MGI:3625331", "url": "https://alliancegenome.org/gene/MGI:3625331#orthology", "database": "AGR" }, { "id": "RGD:1560494", "url": "https://alliancegenome.org/gene/RGD:1560494#orthology", "database": "AGR" }, { "id": "FB:FBgn0031169", "url": "https://alliancegenome.org/gene/FB:FBgn0031169#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9PWH4-1", "protein_name": "ATP-binding cassette, sub-family A member 15", "gene_name": "Abca15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASWESRKLLLLLWKNFTLKRRKFGTLVSEIVLVLLLSIVLLTTRHLLSIKKIEALYFPDQPISTVPSFFRASVTSFYPWELAYVPSNIMVVENIVKNVKNDLNLHMKVIGFPSESDFEDYARSTVNSRNILAAIVFGHNFANSSDPLPKKVKYYLRFSDIKKNINSGAYYQGDTWLTKFLFHSLRLVGPRNPYEADGGSPGYITEGFLAVQHALDKAIMLHHGGADAAALFNDISLFIQRFPYPAYYHDYFYLFATTFIPLTVACTFFFNHYVLVWSIVWEKENRLKEYQLMIGLRNWMFWVAYFFTFLCLYFINIIVMCMVLFVKIEPAPIFQYNDPTLVFIFLLFYAISSIFFSFMVSTLFNKVSLAMSLGSFLFFLTYFPAVAMHQSFERMPSKQKLIWSFDFNVGMAFGFRFLVNTDAKKTGMKWSNIFLSTDSDSFLFAYVLGMLLADAFIYGLVAWYIEAVFPGEYGVPKPWNFFLMHSYWFGEPPQQKLEITQFYERVESKYFEAEPTDLTAGIQIKHLHKVFQKNNTTKVAIKDLSLNLYEGQVTVLLGHNGAGKSTTLSILSGLYPPTSGEAYVHGEDISQHMDQVRNSLGLCPQQNLLFDHLTVSEHLYFYCRIKGVPQKMYLEETNNMLSAFNLMEKCDAFSKSLSGGMKRKLAIIIALIGGSKVAILDEPTSGMDPASRRSTWDILQTYKQNRTILLTTHYMDEADVLGDRIAIMVRGTLRCCGSSVFLKRLYGVGSHLVMVKEPYCDIAEISKLIHSYVPTATLETNVGNELSFILPKEYTHRFEALFTALEENQENLGISSFGVSITTMEEVFLKVSNLEDSKTDIEATQSPSVGSKGNKNGDVESSGRVGFPTQSEDQNIVFNTGCSLYLQQFRAMFMKRLMYNWRNWRGILVQILGLIISTFLLLKSHEFRYKKIRQMNLDEYGQTIVPFSIWGKSNLTSSLLTHLENMLKPGNHQLKEVQGDLLKYLEGNDECVHLCVIALSIKVVANRVNLTVLFNNEAYHSPSLSLTVLDNILFMSLSGSDASITVFNKPQPSPQRKEWPGSTDGKIVAFKIQLGMALLVSGFCILTVTERHNKTKHMQFLSGVSILVYWLSALVFDLIIFFISCCFLLVMFKYCKFDIYVTDYHILDTMLILTLFGWSAIPLTYLLSFLFSKSNSAYINLLVFCYLSGTLSLLMDTIIEARISTIMSNSTQTFLLNALLLFPMYNLGKCISEYTVIYRKKMLCIQQKNALKYLNCSNKHTKKNIYSLKKPMLGKYLIAMSIAGFVFLLLIFFWENISWKVKMFIHQHIYFGACKKYKPDIISKELSGTSEDNDVENERREILYQPEKFLNCPVLIKELTKIYFKSPLILAVKNISLAIQERACFGLLGFNGAGKTTTFQILTGENIPTAGDVFIDGISLTKNIVKVRSKIGYCPQFDALLEYMTGWEIMIMYARIWGISEHQIQPYVKKYLNSLDLESHANSLISTYSEGNKRRLSTAIATMGKPSVIFLDEPSTGMDPRARRLLWDTVIKIRESGKAIIITSHSMEECEALCTRLSIMVRGRLTCLGSPQYLKNKFGNIYILKAKVKSGETLDEFKNFITLTFPGIELQQENQGILNYCIPRKNNSWGKVFGILEKAKEQYNLEDYSISQITLDQVFLSFADQDRK", "length": 1668 }, "evidence": [ { "id": "MGI:2388709", "url": "https://alliancegenome.org/gene/MGI:2388709#orthology", "database": "AGR" }, { "id": "RGD:1305981", "url": "https://alliancegenome.org/gene/RGD:1305981#orthology", "database": "AGR" }, { "id": "FB:FBgn0031169", "url": "https://alliancegenome.org/gene/FB:FBgn0031169#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PWJ7-1", "protein_name": "ATP-binding cassette, sub-family A member 16", "gene_name": "Abca16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNQLTVNQLTVLLWKNFTLKKRQIISTSAELLAALLFVIMLLIFRALTDMNIAGPYHFTAQPIAIMPSFIKDAQEWELVYIPSEIDVVREIIEDVKRNLNTTIKVRGFPSEAEFEEYILFDNMSQKVLAAIVFDCGFKNKSDPLPLQVKYHLRFVGAQRTIWWPDKLGWKTRLLFPNHPSIRPRNPNYLDGGSPGYIKEGFLAVQHALDKSIMLYHESSAGKKLFDEIDTVIQRFPYPSHPQDKLLWISSPFIPLMFILMFSSIVLSIMRSIVFEKEKRLKEYQLIMGLRNWIIWIGYFFTFFPLYVIIILLICILLFIVEEPILRYSDCSFIFVFLTCYAIASICFAFMVSTFFSKTRLAASAGNLLFFASFFPYNFISEYYGMLNLTTKITACLSANVALALGINILIKLEIQEIGVKWHNLWTPANLEDNLNFGYMLGMLLFDAFLYSLVTWYVEAVFPGQCGVPQPWYFFLMRSYWFGKPKIRKTTEEAKCTPIVHNCYEAEPPNLEAGIHIMHLHKEFKNKPAVNNLSLNIYEGQVTVLLGHNGAGKTTTLSVLTGVYPYASRVKAYINGYNISDNMIEVRKDLGFCPQHDLLFDDLTLSEHLFFYCMVKGIPQNINCEEIDRMLSAFNLQENYHTLSGSASGGVRRKLSIVLALMAGSKVVILDEPSSGMDPVSRRATWDILQHYKHNRTILLTTHYMDEADVLGDRVAIMVRGTLHCCGSSVFLKQIYGAGYHIVMEKQQYCDVDNIIAMIQQHVPGAVLENNIENELSFILPKKYVSRFETLFTELEMRQKALGIASFGASITTMEEVFVKVNKLATPQKSIQTIQPYYLAYRKMRQDEQQNVNMPINYSKPNFPYLSEIATVKFNTGVPLYRQQFYSLFIKRALFISRNWKFMLLQIIVVMVVTTYLLLALHLNNNDIPERELNLSHYGRTIVPYSTSGNSDLALNLTKNLNIFLKSKNQNLRKIRGDMNDYILKNKDCHTFCLVALSIKVERNKTVLTIFFNNEAYHSPAISLSILDNILFMTLSGPDASITVFNKPQPLPHYGSNIVPVNGLQIVQCLAFGISVVVGSFSIQTVTERTSQAKHIQFLTGVCVHTYWLSALLCDLIFFFFACCVLLAIFKFCQLEAFVVHYNFLDTILIFMLYGWCVVPLTYIASFLFNSSTAAYIKITLFNYFSTMFSIIIYTIIQFYGNDFPNFVHILIRAILMALPSYNLAMSISKYFDDYEVKRLCAREFKSIYLDCSDPYTQNNVYGFGEHGIGKFLITLATIGLVFLLLLLSLESVSCSLKSFVFRNIIFYFYNKLRKGRNAIPSNQRTKEDEDEDIKKEKGKVFTLLLRLQNTPLLLNEVTKIYFKCPVVKAVKNISLVVKKSECFGLLGLNGAGKTTTFKMLTGEETITSGIAFIDGNSVTRTPRKIRSRIGYCPQTESVLNHMTGRESLVMYARLWGVLEQDINEYVEAFLHSVHLEPIADQFIHTYSAGSKRRLSTAIALMGKSSVVFLDEPSIGMDPVAQHLLWETITWICKTGKAIIITSHRMEECEALCTRLAIMVKGRFTCLGTPQHVRKRFGHVYTLTVRINIAKDEDKVEEFKNFIKVTFPGNIKFQEFHGTIGYYIPSKEIYWGKVFAILEEAKVLFKLEDYSVKRVTLEQIFLTFANTDKMRTYQEIKLQ", "length": 1678 }, "evidence": [ { "id": "MGI:2388711", "url": "https://alliancegenome.org/gene/MGI:2388711#orthology", "database": "AGR" }, { "id": "RGD:1563534", "url": "https://alliancegenome.org/gene/RGD:1563534#orthology", "database": "AGR" }, { "id": "FB:FBgn0031169", "url": "https://alliancegenome.org/gene/FB:FBgn0031169#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PX95-1", "protein_name": "ATP-binding cassette sub-family A member 17", "gene_name": "Abca17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVLKKLKLLLWKNFILKRRKTLITLLEMLMPLLFCAIVLYLRLNSMPRKKSSTNYPAVDVSLLPVYFYNYPLKSKFQLAYIPSKSETLKAVTEVVEQTFAVDFEVLGFPSVPLFEDYIIKDPKSFYILVGIIFHHDFNSSNEPLPLVVKYDLRFSYVQRNFVSPPRHLFFQEEIEGWCTAFLYPPNLSQAPREFSYADGGNPGYNKEGFLAIQHAVDKAIMRHHAPKAALNMFKDLHVLVQRFPFGPHIQDPFLVILQNEFPLLLMLSFICVELIITNSVLSEKERKQKEYMSMMGVESWLHWVAWFITFFISVSITVSVMTVLFCTKINRVAVFRNSNPTLIFIFLMCFAIATIFFAFMMSTFFQRAHVGTVIGGTVFFFTYLPYMYITFSYHQRTYTQKILSCLFSNVAMATGVRFISLFEAEGTGIQWRNIGSVWGDFSFAQVLGMLLLDSFLYCLIAFLVESLFPRKFGIPKSWYIFAKKPVPEIPPLLNIGDPEKPSKGNFMQDEPTNQMNTIEIQHLYKVFYSGRSKRTAIRDLSMNLYKGQVTVLLGHNGAGKTTVCSVLTGLITPSKGHAYIHGCEISKDMVQIRKSLGWCPQHDILFDNFTVTDHLYFYGQLKGLSPQDCHEQTQEMLHLLGLKDKWNSRSKFLSGGMKRKLSIGIALIAGSKVLILDEPTSGLDSPSRRAIWDLLQQQKGDRTVLLTTHFMDEADLLGDRIAILAKGELQCCGSPSFLKQKYGAGYYMTIIKTPLCDTSKLSEVIYHHIPNAVLESNIGEEMIVTLPKKTIHRFEALFNDLELRQTELGISTFATSVTTMEEVFIRVCKLADPSTNVLTEKRHSLHPLPRHHRVPVDRIKCLHSGTFPVSTEQPMRLNTGFCLLCQQFYAMLLKKITYSRRNWMLVLSVQVLLPLAIIMLSLTFFNFKLRKLDNVPLELTLQTYGQTIVPFFIAENSHLDPQLSDDFVKMLVAAGQVPLRIQGSVEDFLLKKAKEAPEGFDKLYVVAASFEDVNNHTTVKALFNNQAYHSPSLALTLVDNLLFKLLSGANASITTTNYPQPQTAIEVSESILYQGPKGHYLVVNFLFGIAFLSSSFSILTVGEKSVKSKSLQFVSGVSTAVFWLSALLWDLISFLVPTLLLVLVFLWYKEEAFAHHESIPAVVLIMMLYGWAVIPLVYTVSFSFNTPGSACVKLVVMLTFLSISPVVLVTVTSEKDLGYTELSDSLDHIFLILPGHCLGMALSNLYYNFELKKFCSAKNLSDIDCNDVLEGYVVQENIYAWESLGIGKYLTALAVLGPVYITMLFLTEANAFYVLKSRLSGFFPSFWKEKSGMIFDVAEPEDEDVLEEAETIKRYLETLVKKNPLVVKEVSKVYKDKVPLLAVNKVSFVVKEEECFGLLGLNGAGKTSIFNMLTSEQPITSGDAFVKGFNIKSDIAKVRQWIGYCPEFDALLNFMTGREMLVMYARIRGIPECHIKACVDLILENLLMCVCADKLVKTYSGGNKRMLSTGIALVGEPAVILLDEPSTGMDPVARRLLWDTVERVRESGKTIVITSHSMEECEALCTRLAIMVQGQFKCLGSPQHLKSKFGISYSLQAKVRRKWQQQMLEEFKAFVDLTFPGSNLEDEHQNMLQYYLPGPNLSWAKVFSIMEQAKKDYMLEDYSISQLSLEDIFLNFTRPESSTKEQIQQEQAVLASPSPPSNSRPISSPPSRLSSPTPKPLPSPPPSEPILL", "length": 1733 }, "evidence": [ { "id": "MGI:3625331", "url": "https://alliancegenome.org/gene/MGI:3625331#orthology", "database": "AGR" }, { "id": "RGD:1560494", "url": "https://alliancegenome.org/gene/RGD:1560494#orthology", "database": "AGR" }, { "id": "FB:FBgn0031169", "url": "https://alliancegenome.org/gene/FB:FBgn0031169#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8F8-1", "protein_name": "ATP-binding cassette, sub-family A member 14", "gene_name": "Abca14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSLQMKQFSVLLWKNFLLKSRNVVGLVVEIILIFLLFVWTLTVRRISKKTSISDVIFNPILLTLPKFLNENFDYELAYVPSESNAARNITEMVKKDLNFNFKVQGFPSEESFERYIKYENKDAHVLAAIVFDHKFKTSNERLPLQVKYSLRFGRIYDPENLFQPSKYQKEIEWNTSTLFPSVPSLGPRNFLENDGGNPGYIREGFLIVQHSVDKAIMMYHSGRAAEDIFANTTIYAERFPHPAFIHDSFLWTFIAMFPWTILFTFTQMALVIVGTIMLEKEKRLKEYQLMVGLSNAMLWVSYFITFLLMYFIIICLLCGILFLKITHERVFQHSDPLFIAFYFMCFAVSSVLLGFLISTLFNKASLATSIAGFLHFLTFFPYLILYHKYDQISLSGKLALCLITNTALAFGTDLICKLEMKGHGAQWNNFATKVNADDDLTLAHIIGMFLFSAFLYGLVAWYLDAVFPGTYGVPKPWNFFLQKAYWFGEPALSREESQVSDLLSSDFMEPEPVGLVAGIRIQHLYKEFILKNSTLMAVNDLSLNLYEGQITVLLGHNGAGKTTTLSILTGLYLPTRGKVYISGYDISSDMVQIRKSLGLCPQDDLLFPMLTVSEHLHFYCVIKGIPLQNQSRETNRMLTSFGLLQQSNTMSKDLSGGMKRKLSIIIALIGDTKVVILDEPTSGMDPVSRRATWDLLQHYKKDRTILLTTHHMDEADVLGDRIAILVMGILKCCGSSLFLKKLYGVGYHLVIVKTPDSNDEKIFQLIKNYIPTAKMETNVAAELSFILPKEHTHRFAELFTDLEEKQEELGISGFGVSMTTMDEVFFKVSNLEDLKLNTEIAPSASIVSQSSNEDNQNMNVPRNFERPGYSRRHLDSSFNAGWSLYIQQFRAMFIKRVMFSWRYWKLLLLQLLALLGLMYLLIKGISFSVPKEPARVMDLEQYGETIVPFSVSGDPNLTQILTKNLETMLKAKKQKIHEVQGDMKNYLLTSKDCIYSCIVAFSLDVTTEEKTFIFWFNNEAYHAAPLSLSILDNIIYKYLSGPDATITVSNNPQPQRVTKDKSNERSISGIQIVFNLLFGMSIFTSGFCLMTVTERVSKAKHIQFVSGVYTLNFWLSALLWDLIIHFVACVLLLVVFLYTDVDILLEKYHFLDTMFILMLFGWSIIPFIYLLSFWYNNSTNAYIKIFVFNHCLGFISIIVDAVVQIIPDIKTSTKNLILNSMLLLPIYNFGMSIYKYYNIHEIRKLCSSLGYINTIPSCKSQIIDIPIYSMNQKAIGRHVTAMAATGLIYFILIILLETTSWNLKIFIYRYVLFGIYRIFYKARMSEELSGYSEEEDVQNERETILNHPWRSLNSTVLIKELIKIYFKIPPTLAVRNISVAIQKEECFGLLGLNGAGKTTTFKILTGEEIATSGDVFIEGYSITRNILKVRSKVGYCPQFDALLDYMTSREILTMYARVWGIPENSIRAYVDNLLKMLYLKPQADKFIYTLSGGNKRRLSTAIAIMGNSTVVFLDEPSTGMDPLARRMLWNAVIKTRESGKVIIITSHSMEECEALCTRLAIMVQGKFVCLGSPQHLKNKFGNIYTMTIKFKTDTDDNTVQDLKDFIAEVFPGSDLKQENQGILNYYIPSKNNSWGKVFGILEKAKEDYNLEDYSISQITLEQVFLTFANPDNPRSGYEKAVP", "length": 1683 }, "evidence": [ { "id": "MGI:2388708", "url": "https://alliancegenome.org/gene/MGI:2388708#orthology", "database": "AGR" }, { "id": "RGD:1561491", "url": "https://alliancegenome.org/gene/RGD:1561491#orthology", "database": "AGR" }, { "id": "FB:FBgn0031169", "url": "https://alliancegenome.org/gene/FB:FBgn0031169#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1M2Q5-1", "protein_name": "ATP-binding cassette, subfamily A (ABC1), member 14", "gene_name": "Abca14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCHRASTLSGKMDSLLMRQFLVLLWKNFLLKSRKVFGLVVEIILIFLLFVWTLTVRRISKKKFIPAMIFNPIPLTLPGFLNQNFDYELAYVPSDSNAARNITEMVKKDLNFNFKVQGFSSEESFEKYIKYEDKAEHVLAAIVFDHKFKTSNEPLPLQVKYSLRFGRMYDPENVLKPSERQKETEWNTSILFPSVPSLGPRNVLENDGGNPGYIREGFLLVQHSVDKAIMMHHSGRAAEAMFANTTIYARRFPYPAFIHDNFLWTFIVMFPWTILFTFTQMALDIIGTIMLEKEKRLKEYQLMVGLSNAMLWVSYFITFLLMYFIIICLLCGILFLKITHERVFQHSDPLFIAFYFLCFAISSMLLGFMISTFFNRASLATSIAGFLHFLTFFPYLIVFSLYDQTSLSGKLALCLITNTALAFGTDLICKLEMKGHGAQWYNFATKVNPDDDLTLAHIIGMFLFSAFLYGLVAWYVDAVFPGKYGVPKPWNFFLQKTYWFGEPALSREESQVSDLPPSDFMEPEPVDLEAGIQIQHLYKEFTLKNSTLMAVKDLSLNLYEGQITVLLGHNGAGKTTTLSILTGLYLPTKGKVYISGYDISSDMVQVRKSLGLCPQDDLLFPLLTVSEHLYFYCVIKGISSTNRPREIHRMLTSFGLLQKSNTMSKDLSGGMKRKLSIIIALIGDTKVVILDEPTSGMDPVSRRAIWDLLQHYKKDRTILLTTHHMDEADVLGDRIAILVMGVLKCCGSSLFLKKLYGVGYHLVIVKTPDSDDGKISQLIKNYIPTAEMETNVAAELSFILPKEHTHRFAELFTDLEERQEELGISGFGVSMTTMDEVFFKVSNLADLKLNTEIAQSASTVNPSTSENNENMNVPRNFERSGYSGRYSDSSFNAGWPLYMQQFRAMFIKRVMFSWRNWKLLLLQLLALQGLTYVLIKGIGFSVPKEPARVMDLEQYGETTVPFSVSGDPPLTQKLTKNLEIMLKDKKQKVHEVQGGVQDYLLTNKDCIYSCIVAFSLDVTRKEKTFTFWFNNEAYHASPLSLSILDNIIFKYLSGPDATITVSNKPQPQPFTKGRSEERSASGIQIVFNLLFGMSIFTSGFCLMTVTERVSKAKHIQFVSGVYTLNFWLSALLWDLIIHFVACVLLLLVFLYTDVHILLENYNFLDTMLILMLFGWSIIPFIYLLSFWYNNSTNAYIKIFVFNHCLGFMSIIVDAVVELIPDIKTSTKNLILNSLLLLPIYNFGMSIFKYYSIQEIRKLCSSLGSLNTFSGCQHERKYLITVYSMDKRAIGRHVTAMAATGLIYFLFIILLETTSWNLKAFIYRYVLFGIYKIFYKARMSKELSGDSEDEDVQNERETILQHSWHSLNSTVLIKKLIKIYFKIPPTLAVRNISLTIQKEECFGLLGLNGAGKTTTFKILTGEEIATSGDVFIEGYSITRNILKVRSKIGYCPQFDALLDYMTSREILTMYARVWGIPENNIRSYVNNLLKMLYLKPQAEKFIYTLSGGNKRRLSTAIAIMGNSSVVFLDEPSTGMDPLARRMLWNAVIRTRESGKVIIITSHSMEECEALCTRLAIMVQGKLVCLGSPQHLKNKFGNIYTMNIKFKTGTDDDVVQDLKNYIAEVFPGSDLKQENQGILNYYIPSKDNSWGKVFGILEKAKEDYNLEDYSISQITLEQVFLTFANPDNTESGYEKAVP", "length": 1695 }, "evidence": [ { "id": "MGI:2388708", "url": "https://alliancegenome.org/gene/MGI:2388708#orthology", "database": "AGR" }, { "id": "RGD:1561491", "url": "https://alliancegenome.org/gene/RGD:1561491#orthology", "database": "AGR" }, { "id": "FB:FBgn0031169", "url": "https://alliancegenome.org/gene/FB:FBgn0031169#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9VDR4-1", "protein_name": "ABC transporter domain-containing protein", "gene_name": "CG11460", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNRNLTYCQKYRLLLWKDIKLQLTNWVELVMIIFLSALMPIFFSIGTKVAKSIFPPDIEMEKSPGPKSVNTSLFVDLYFTPNNGILEQLITQLANISEFKSVEVFDTNSELYLQLMINRNAIGIAFPSEWYDIKSCPEVLNLTIFMPLSIKRKDFKYFESGFLLLQERISKIFIFFKNAGNGKIPRVLMNHFPYPSYVPNHYAESAKAMTYMTLISFFLPCITIAKYVVAEKERHQKAVLTAMGFSNSIHWLAWYTKSMLLLLLCLLIMISIFSIGLIYEFSSLVCLMTIFLVYIHSLVLFAFFISSFFSRSLSAVVATILMYFSTALPFLIVGAENSSVAAQTAASIGLNSALFYILDSVAVMEMQSVGAQWYTIDNTASSGYKLSIVGYMLIMISISWIELLICLYIEAVRTGEFEVPQPWSYPFQRRYWCPLRYGSSVFHQGALLPLAGKNSEGNLPAAHPTRQPIIYLDDRTQENFQRVNISKKIGIEVRSLSKTFGFRNVVKDLFFNVYENEITALVGHKGSGKTTIIMMLCGILQPTTGTVLINGYDIVTEAKVAKSSLGICPQHSVIFKGMSARDHIYFFSRVKGYNKTEAMMESNIYISKLGLVDSQKWDAMRLSPGNQRRLSLACALCAGSKVILCDEPSSGLDPIGRHELMRFLQKEKHGRTILMTTQQLEEGEILADRIAIMNDGQILCYGTLGYLKQLPFTSYTLSCQMAPNSKADNLTDLVRLYMTTTTSPVFHGVDVSYKLPRSQIDRFPEFFQQLEENKKSLNVVSFGVSDSTLDGIYLSLDYGQGSSRLRGGADPGVNDKVEFGVQTDKAIRTKDRANNSLVRYQHQVDPPNETILNTKTPINPIEIWRPIDREKGSCMAQWQAMFIKKKNYTASRALIFILILIIPLFYYIIVLGTAASEKCAHRTDKQPVLPLSLDYYSYDDMIILLEVDKQLYKSEGEAYVQLVKEPATVESVDSIFSHLLKAPPIIRRDIKRKYVCGASFNNASTITAWFNSDAFEHSAPIALNLVYNALGKAVFEDQDFSILVNRGDLHDFIWLNNASSMRRRYKRQNDPDYTDYSDYEIQEYDVVVKPNSSSTSGQHNKSNPGDDNIITVQMSIIEAASTLYNEKGKRKQLFGTLIIITAYIALCLSIFSIFVTKERVEHFKMQQEIYGVTLFYFWSTHFVGDFLIYAIYMGALTIAIYHFTIWYQVVVMLLLIGFACLPFVYLCSLLFSLPNIAFAGIFAILVMTGGMLFSFMYMLTLITDVNFTTVFAILPMYVGTFGLFKCLAWREYCNREVLPPIEELDCKFGNCNVFCACKPERTWMEVWLLMVHCLVWFIFLWFSNFGYEIGYRFKPKLSNRIWHNNEKHIRVLDEERRVGLIPKYEHEDYPIIVDQVTKNYCRAKNAVQLVSFAIRPGDTFGLLGAQGAGKTSIFQMIAGETSMSHGNIYVRGHSLREHRNAAKMEVGFCPQGDNAPKYLTGRQLLRIHCLLHGVPKDHIKAVSEQMAIEFNFKDQLDRPIHTYSGGKKRKLNIALAIDSGSVLCLDDTNGSVDHATQRFIWRKLEAVKRSGRPVLLTTQSMEEANAVCSRVAFLVAGEMMFIGSLQQVRSEVSNTIVIRLRVNPSDGKLKRRFQQLIADMAELFPLATLHEALETCLIYHININVTTLANLFYQMEKIRNEGLLEDYSITQVSLDEIYRILNDEEDPNLVDLDSTHNSEVLEDIRDTTRDTTRGTTRDTNLVSDEGIQKEKVKRKKVEEEDRDRQESTETSKPKVKRSPATQSDSTDTDEMEVEKGEKLKKKTSTFFQD", "length": 1809 }, "evidence": [ { "id": "MGI:2388709", "url": "https://alliancegenome.org/gene/MGI:2388709#orthology", "database": "AGR" }, { "id": "MGI:2388708", "url": "https://alliancegenome.org/gene/MGI:2388708#orthology", "database": "AGR" }, { "id": "MGI:2388711", "url": "https://alliancegenome.org/gene/MGI:2388711#orthology", "database": "AGR" }, { "id": "MGI:3625331", "url": "https://alliancegenome.org/gene/MGI:3625331#orthology", "database": "AGR" }, { "id": "RGD:1561491", "url": "https://alliancegenome.org/gene/RGD:1561491#orthology", "database": "AGR" }, { "id": "RGD:1305981", "url": "https://alliancegenome.org/gene/RGD:1305981#orthology", "database": "AGR" }, { "id": "RGD:1560494", "url": "https://alliancegenome.org/gene/RGD:1560494#orthology", "database": "AGR" }, { "id": "RGD:1563534", "url": "https://alliancegenome.org/gene/RGD:1563534#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VRG4-1", "protein_name": "ATP binding cassette subfamily A member 3, isoform B", "gene_name": "Abca3", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAKVTNWDKFVLLLWKNWTLQWNHKWQMVIELVLPAIFSLLLVLVRTLVDTEQKGVRYYNEQNLTDLNLLQHSLHRSSYLGKLIALIAPNRRRKNGGFSKFEFILCYSPVNPVLKKLVEEAWQSLGKNKICESENATQLELDTVSKNAFAGVQFDDAWANLTENDPLPNDFHFALRFPAELRTATIAIANTWLTMRLFPTIDLTGPRNEGDDDGGIPPGYLREGFLPLQHSLSMAYLRQKSGEQDLPNVVMKRYPFPAYIFDPLLEGMSSIMSLIILLSFIYPCTYITKYITAEKEKQLKEVMKIMGLSNWLHWTAWFVKSFIMLTISAILIAILVKINWSEDVAVLTHANFTALVFFLIIYIVSSICFCFMMATFFSRASTAAAVTGLIWFIAYIPYSFTINSYDDLSLSSKLGWSLISNTAMGFGIKLILGFEGTGEGLQWSNFFTPVSVDDTLTLGAVMIMMLVSCVIYMIICLYVEQVMPGSFGVPRPWNFPFTREFWCGEREYTGVEDIPNGHVEQRDPKAFETEPEGKHIGLQMRHLKKRFGNKMVVKGLSMNMFEDEITVLLGHNGAGKTTTISMLTGMFPPTSGTAIINGSDIRTNIEGARMSLGICPQHNVLFDEMSVSNHIRFFSRMKGLRGKAVEQEVAKYLKMIELEDKANVASSKLSGGMKRKLSVCCALCGDTKVVLCDEPSSGMDPSARRQLWDLLQQEKVGRTLLLTTHFMDEADVLGDRIAIMCDGELKCQGTSFFLKKQYGSGYRLICVKRDDCETNEVTALLNKYIPGLKPECDIGAELSYQLPDSASAKFEEMFGQLEEQSDELHLNGYGVGITSMEEVFMKVGAEKDNTGNIKDQHEIMNGGSGFRGEDDNESVQSDGIFSENRRLLQGLQLLSNQWKAMLLKKFLYTWRNKLLLLIQNIMPVFFVVVTILIIKTQGTFQELKPITISLTQYPLAVTVLDRSNVQNGTGYEIANKYEDLARSYGSNYGLELTGTQGFEDYILDLGKTIQVRINSRYLVAATITESKITAWLNNQALHTAPLTVNMVHNAIADKLFGSSVKIQVTNAPLPYTTSTLLSQLSTGNNLGTQLASNLCFCMCFVSSIYILFLIKERESRAKLLQFVGGVKVWTFWLSQFICDFASYIVTALIVVITIVCFQETGLSTFGELGRYYLLLLLFGFAVLPFIYIMSLFFREPATGFARVSIVNIFCGMALFIVVVVMSSELFDTKDTADILGWIFRIFPHFSLAMSLNKVYTNTATRNACAKAGALPPILLCELVPQCCNLKPYFAWEEPGVLPETVYMAVTGVVFFLIIIVLEFRLINELMFKIRQLISKPPPPPTEGQLDDDVANERERILQMSSNELATKNLVLDRVTKYYGQFMAVNQVSLCVQEVECFGLLGVNGAGKTTTFKMMTGDERISSGAAYVQGLSLESNMNSIYKMIGYCPQFDALLDDLTGREVLRIFCMLRGVQESRIRQLSEDLAKSFGFMKHIDKQTHAYSGGNKRKLSTAIAVIGSPSVIYLDEPTTGMDPAARRQLWNMVCRIRDSGKSIVLTSHSMEECEALCTRLAIMVNGEFKCIGSTQHLKNKFSKGLILKIKVRRNLEALRQARLSGGYARNPDEQTVPAQMSQRDIDAVKEFVETEYPNSILQEEYQGILTFYIPLTGVKWSRIFGLMESNRDQLNVEDYSVSQTTLEEIFLEFAKYQREDTRANQ", "length": 1714 }, "evidence": [ { "id": "MGI:2388709", "url": "https://alliancegenome.org/gene/MGI:2388709#orthology", "database": "AGR" }, { "id": "MGI:2388708", "url": "https://alliancegenome.org/gene/MGI:2388708#orthology", "database": "AGR" }, { "id": "MGI:2388711", "url": "https://alliancegenome.org/gene/MGI:2388711#orthology", "database": "AGR" }, { "id": "MGI:3625331", "url": "https://alliancegenome.org/gene/MGI:3625331#orthology", "database": "AGR" }, { "id": "RGD:1561491", "url": "https://alliancegenome.org/gene/RGD:1561491#orthology", "database": "AGR" }, { "id": "RGD:1305981", "url": "https://alliancegenome.org/gene/RGD:1305981#orthology", "database": "AGR" }, { "id": "RGD:1560494", "url": "https://alliancegenome.org/gene/RGD:1560494#orthology", "database": "AGR" }, { "id": "RGD:1563534", "url": "https://alliancegenome.org/gene/RGD:1563534#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VVJ9-1", "protein_name": "ABC transporter domain-containing protein", "gene_name": "Dmel\\CG6052", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKSERESFSTSEIYAVGDWDKLKLLMWKNWILQWNQKMQIVFALVLPVLFLCLILVLRIIVLPEKMDEIRYPTVSISDLNLYMRMVPLGNRILHENGSLNIPRNFLCYTPNNPINSAIVGATAIRLRLLGTRAYDTALHMEQDMVLHNFLAGVQFEDNENVNTNDAGYPLNLNYSLRFPSELRTMQGPIIDTWRTSRLFLSYDTSGSRNRLDNDGGVPVGYIREGFLPIQHALTMSWLALASGVTDTGIPAIHLQRFPYRAYTYDQLLSGLRQLLPFVILLSFIYPASTVTKYVTSEKELQLKEIMKLIGVHNWLHWVAWFVKSYIMLMLVVFLIMSLIMVKFYASVAVLTFSSWVPVLLFLHTYVVTSVCLCFMLAVLFSKASTASAVAAIFWFLTYIPYSFGYYYYERLSLMSKLLISLIFSNSALGFGIHVIVMWEGTGEGITWRNMFHPVSTDDSLTLFYIIMTMSFGSIMFISICLYVEQVFPGEYGVPRRWNFMCHKNYWRQYVPSLNIVPSFQTILHGSAKAKSCRRAREVGIQLFNLQKNYGKLKAVKGISLKMHRNEITVLLGHNGAGKTTTINMITGIVKPTSGTAIVNGYDIRTHLAKARESLGICPQNNILFKEMSVRDHIIFFSKLKGIRGTKAVENEVGKYMTMLKLQDKSYVAAKNLSGGMKRKLSLCCALCGNAKVVLCDEPSSGIDAAGRRSLWDLLQSEKDGRTILLTTHYMDEADVLGDRIAILSEGKLQCQGTSFYLKKRFGTGYLLVCIMQSGCDVGAVTQLIRKYVPPIKPERVLGTELTYRLPTEYSKKFAELLQDLDEKCAQLQLVGYGLSGATLEDVFMAVNTDKRVQGGAEGPPVDGSIDFKELVFDSKTREKRRIRRCFMFWQALFLKKFYTTTRNYWLLGIQLVLPIAVMALTILNSRGGRIYYELPAMPISINQYSSAYVVLEDNTTDKTSSLADAYSKHLEHYARRCTLLRTGDLKFEDYILSHDVNHSRRIDFHFLAGLTVSENNFIVWLNNKPLHTAPLTLNLLHNALAIKLLGQDASTYVTNEPLPYSDDTRTLRLNKGQVLGAEISINLSLTMCFITAFYAIPIIRERETRAKLLQFLSGVDVCAYWTSHIVWDYLVFVLSALSSILTIAAFKEIGYITPLDLSRYFYMLLIFGFPGIMLSYAASGCFSDAATGFTRISIINTLMGTGLFLMFMTLNFEAFQLKDVAEKLAWYFRLSPHYSLASSTHSIHIGYNIRRGCSIGGIRKLPKQLRCRNVPICCDIPGYYGWRKPGVLVEITYMIMLGSTLFLLIVMHDAKVCNLIAEKLGNCFSKRKRVEGGTSIENDSVVAEQRVVREMINSGRKDVPLLVYKISKRYRSKLAVKAISFHVPHAECFGLLGINGAGKTSTFKMLAGDEKITSGEAYIDGTNISTHKVYRKIGYCPQFDALFEDLTGRETLNIYCLLRGVQRRHVTPICWGLAISFGFAKHMDKQTKHYSGGNRRKLSTAISVLGNPSVLYLDEPTSGMDPAARRQLWQIIGLIRTAGKSIVLTSHSMDECEALCSRLAIMVDGEFKCLGSVQSLKNQFSKGLILKVKVKHKKKTFQRVVEDSSSSNDKKSISETDLKFLQMASVMESSQADRILKVNRFISKEIPDAELKEEYNGLITYYIPHSKTLSKIFQLLETNSHKLNIEDYLIMQTRLEEIFLDFASKRDSSDIFTKRIYSCSWPPVS", "length": 1725 }, "evidence": [ { "id": "MGI:2388709", "url": "https://alliancegenome.org/gene/MGI:2388709#orthology", "database": "AGR" }, { "id": "MGI:2388708", "url": "https://alliancegenome.org/gene/MGI:2388708#orthology", "database": "AGR" }, { "id": "MGI:2388711", "url": "https://alliancegenome.org/gene/MGI:2388711#orthology", "database": "AGR" }, { "id": "MGI:3625331", "url": "https://alliancegenome.org/gene/MGI:3625331#orthology", "database": "AGR" }, { "id": "RGD:1561491", "url": "https://alliancegenome.org/gene/RGD:1561491#orthology", "database": "AGR" }, { "id": "RGD:1305981", "url": "https://alliancegenome.org/gene/RGD:1305981#orthology", "database": "AGR" }, { "id": "RGD:1560494", "url": "https://alliancegenome.org/gene/RGD:1560494#orthology", "database": "AGR" }, { "id": "RGD:1563534", "url": "https://alliancegenome.org/gene/RGD:1563534#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VVK6-1", "protein_name": "ABC transporter domain-containing protein", "gene_name": "Dmel\\CG42816", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": 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"https://www.uniprot.org/uniprotkb/Q9VRG3" } ], "pmid": "" }, { "name": "ABC-type transporter activity", "id": "GO:0140359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140359", "evidence": [ { "database": "UniProtKB", "id": "Q9VRG3", "url": "https://www.uniprot.org/uniprotkb/Q9VRG3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "Q9VRG3", "url": "https://www.uniprot.org/uniprotkb/Q9VRG3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VRG3", "url": "https://www.uniprot.org/uniprotkb/Q9VRG3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1253, "end_pos": 1255, "annotation": 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"NP_001285519", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285519" }, { "id": "Q9VRI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VRI1" } ] }, { "name": "CG1678", "type": "synonym", "evidence": [ { "id": "NP_001285519", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285519" }, { "id": "Q9VRI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VRI1" } ] }, { "name": "Dmel\\CG1678", "type": "synonym", "evidence": [ { "id": "NP_001285519", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285519" }, { "id": "Q9VRI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VRI1" } ] }, { "name": "Dmel_CG1678", "type": "synonym", "evidence": [ { "id": "Q9VRI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VRI1" } ] }, { "name": "whe", "type": "synonym", "evidence": [ { "id": "NP_001285519", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285519" } ] } ], "protein_names": [ { "name": "CG1678-PB", "type": "synonym", "evidence": [ { "id": "NP_001285519", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285519" } ] }, { "name": "What else, isoform A", "type": "synonym", "evidence": [ { "id": "Q9VRI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VRI1/entry#names_and_taxonomy" } ] }, { "name": "What else, isoform B", "type": "synonym", "evidence": [ { "id": "Q9VRI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VRI1/entry#names_and_taxonomy" } ] }, { "name": "what else, isoform B", "type": "synonym", "evidence": [ { "id": "NP_001285519", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285519" } ] }, { "name": "whe-PB", "type": "synonym", "evidence": [ { "id": "NP_001285519", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285519" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VRI1", "url": "https://www.uniprot.org/uniprotkb/Q9VRI1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "whe", "url": "https://www.uniprot.org/uniprotkb/Q9VRI1", "locus": { "chromosome": "X", "start_pos": 21402339, "end_pos": 21402772, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0031176", "url": "https://www.ensemblgenomes.org/id/FBgn0031176" } ] } } ], "crossref": [ { "id": "FB:FBgn0031176", "url": "https://alliancegenome.org/gene/FB:FBgn0031176", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0031176", "url": "https://bgee.org/?page=gene&gene_id=FBgn0031176", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0031176", "url": "https://flybase.org/reports/FBgn0031176", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "33121", "url": "https://www.ncbi.nlm.nih.gov/gene/33121", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VRI1", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VRI1*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "dme:Dmel_CG1678", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG1678", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VQGHRPH", "url": "https://omabrowser.org/oma/group/VQGHRPH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "NP_001285519", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285519", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VRI1", "url": "https://www.uniprot.org/uniprotkb/Q9VRI1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VRI1-1", "url": "https://www.uniprot.org/uniprotkb/Q9VRI1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRVIFLIVVLAMVALAAVQGRRPPGLPQGGLGPLQGSGGLQPPQGIPQGPPQGLPQGPPQGGNSSSSEDSSSQESSSESSSEASA", "length": 85, "header": "tr|Q9VRI1-1|Q9VRI1_DROME Isoform 1 of What else, isoform A OS=Drosophila melanogaster OX=7227 GN=whe PE=4 SV=1 CANONICAL=Q9VRI1-1" }, "isoforms": [ { "isoform_ac": "Q9VRI1-1", "url": "https://www.uniprot.org/uniprotkb/Q9VRI1/entry#Q9VRI1-1", "sequence": { "sequence": "MRVIFLIVVLAMVALAAVQGRRPPGLPQGGLGPLQGSGGLQPPQGIPQGPPQGLPQGPPQGGNSSSSEDSSSQESSSESSSEASA", "length": 85, "header": "tr|Q9VRI1-1|Q9VRI1_DROME Isoform 1 of What else, isoform A OS=Drosophila melanogaster OX=7227 GN=whe PE=4 SV=1 CANONICAL=Q9VRI1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10266:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02167", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02167", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-611105", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-611105", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-9865881", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9865881", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001246637", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001246637", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VRL0", "url": "https://www.uniprot.org/uniprotkb/Q9VRL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VRL0-1", "url": "https://www.uniprot.org/uniprotkb/Q9VRL0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAATLRRFHGLRLLKSAPALSLQQAKNLSSAGSWASGNKKLIGALGAITGGVGALIYALEQSVQASGGEVHSPAQLWNHKGLFDALDHQSVRRGYEVYKQVCSACHSMQYIAYRNLVGVTHTEAEAKAEAEQITVKDGPDDTGNYYTRPGKLSDYFPSPYPNEEAARAANNGAYPPDLSYIVSARKGGEDYIFSLLTGYHDAPAGVVLREGQYFNPYFPGGAISMAQVLYNEVIEYEDGTPPTQSQLAKDVATFLKWTSEPEHDDRKQLLIKVIGILGFLTVISYYIKRHKWSSLKSRKIVFVPKEK", "length": 307, "header": "tr|Q9VRL0-1|Q9VRL0_DROME Isoform 1 of Cytochrome c1, heme protein, mitochondrial OS=Drosophila melanogaster OX=7227 GN=Cyt-c1 PE=1 SV=1 CANONICAL=Q9VRL0-1" }, "isoforms": [ { "isoform_ac": "Q9VRL0-1", "url": "https://www.uniprot.org/uniprotkb/Q9VRL0/entry#Q9VRL0-1", "sequence": { "sequence": "MAATLRRFHGLRLLKSAPALSLQQAKNLSSAGSWASGNKKLIGALGAITGGVGALIYALEQSVQASGGEVHSPAQLWNHKGLFDALDHQSVRRGYEVYKQVCSACHSMQYIAYRNLVGVTHTEAEAKAEAEQITVKDGPDDTGNYYTRPGKLSDYFPSPYPNEEAARAANNGAYPPDLSYIVSARKGGEDYIFSLLTGYHDAPAGVVLREGQYFNPYFPGGAISMAQVLYNEVIEYEDGTPPTQSQLAKDVATFLKWTSEPEHDDRKQLLIKVIGILGFLTVISYYIKRHKWSSLKSRKIVFVPKEK", "length": 307, "header": "tr|Q9VRL0-1|Q9VRL0_DROME Isoform 1 of Cytochrome c1, heme protein, mitochondrial OS=Drosophila melanogaster OX=7227 GN=Cyt-c1 PE=1 SV=1 CANONICAL=Q9VRL0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VRL0", "url": "https://www.uniprot.org/uniprotkb/Q9VRL0" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VRL0", "url": "https://www.uniprot.org/uniprotkb/Q9VRL0" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VRL0", "url": "https://www.uniprot.org/uniprotkb/Q9VRL0" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VRL0", "url": "https://www.uniprot.org/uniprotkb/Q9VRL0" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VRL0", "url": "https://www.uniprot.org/uniprotkb/Q9VRL0" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VRL0", "url": "https://www.uniprot.org/uniprotkb/Q9VRL0" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VRL0", "url": "https://www.uniprot.org/uniprotkb/Q9VRL0" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VRL0", "url": "https://www.uniprot.org/uniprotkb/Q9VRL0" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VRL0", "url": "https://www.uniprot.org/uniprotkb/Q9VRL0" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VRL0", "url": "https://www.uniprot.org/uniprotkb/Q9VRL0" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VRL0", "url": "https://www.uniprot.org/uniprotkb/Q9VRL0" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG4769", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG4769", "resource": "KEGG Pathway" }, { "id": "R-DME-611105", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-611105", "resource": "Reactome", "description": "Respiratory electron transport" }, { "id": "R-DME-9865881", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9865881", "resource": "Reactome", "description": "Complex III assembly" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AZF9-1", "protein_name": "Cytochrome c1, heme protein, mitochondrial", "gene_name": "CYC1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSAAAAASLRGAVLGPRGAGLPGARARGLLCGPRPGQLPLRTPQALSLSSKSGLSRGRKVILSALGMLAAGGAGLAVALHSAVSATDLELHAPSYPWSHRGLLSSLDHTSIRRGFQVYKQVCSSCHSMDYVAYRHLVGVCYTEEEAKALAEEVEVQDGPNEDGEMFMRPGKLSDYFPKPYPNPEAARAANNGALPPDLSYIVRARHGGEDYVFSLLTGYCEPPTGVSLREGLYFNPYFPGQAIAMAPPIYNEVLEFDDGTPATMSQVAKDVCTFLRWASEPEHDHRKRMGLKMLMMMGLLLPLVYAMKRHKWSVLKSRKLAYRPPK", "length": 326 }, "evidence": [ { "id": "Q9VRL0", "url": "https://omabrowser.org/oma/group/Q9VRL0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZFQ8-1", "protein_name": "Cytochrome c1, heme protein, mitochondrial", "gene_name": "Cyc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAAAAASLRRSVLGPRGMGLPGASAPGLLGGARPRHLPLRTPQAVSLSSKSGPSRGRKVMLSALGMLAAGGAGLAVALHSAVSASDLELHPPSYPWSHRGLLSSLDHTSIRRGFQVYKQVCSSCHSMDYVAYRHLVGVCYTEEEAKALAEEVEVQDGPNEDGNMFMRPGKLSDYFPKPYPNPEAARAANNGALPPDLSYIVRARHGGEDYVFSLLTGYCEPPTGVSLREGLYFNPYFPGQAIGMAPPIYTEVLEYDDGTPATMSQVAKDVATFLRWASEPEHDHRKRMGLKMLLMMGLLLPLTYAMKRHKWSVLKSRKLAYRPPK", "length": 326 }, "evidence": [ { "id": "RGD:1306597", "url": "https://alliancegenome.org/gene/RGD:1306597#orthology", "database": "AGR" }, { "id": "MGI:1913695", "url": "https://alliancegenome.org/gene/MGI:1913695#orthology", "database": "AGR" }, { "id": "HGNC:2579", "url": "https://alliancegenome.org/gene/HGNC:2579#orthology", "database": "AGR" }, { "id": "FB:FBgn0035600", "url": "https://alliancegenome.org/gene/FB:FBgn0035600#orthology", "database": "AGR" }, { "id": "SGD:S000005591", "url": "https://alliancegenome.org/gene/SGD:S000005591#orthology", "database": "AGR" }, { "id": "Q9VRL0", "url": "https://omabrowser.org/oma/group/Q9VRL0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P00125-1", "protein_name": "Cytochrome c1, heme protein, mitochondrial", "gene_name": "CYC1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAAAATLRGAMVGPRGAGLPGARARGLLCGARPGQLPLRTPQAVSLSSKSGLSRGRKVILSALGMLAAGGAGLAVALHSAVSASDLELHPPSYPWSHRGLLSSLDHTSIRRGFQVYKQVCSSCHSMDYVAYRHLVGVCYTEDEAKALAEEVEVQDGPNEDGEMFMRPGKLSDYFPKPYPNPEAARAANNGALPPDLSYIVRARHGGEDYVFSLLTGYCEPPTGVSLREGLYFNPYFPGQAIGMAPPIYNEVLEFDDGTPATMSQVAKDVCTFLRWAAEPEHDHRKRMGLKMLLMMGLLLPLVYAMKRHKWSVLKSRKLAYRPPK", "length": 325 }, "evidence": [ { "id": "Q9VRL0", "url": "https://omabrowser.org/oma/group/Q9VRL0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P07143-1", "protein_name": "Cytochrome c1, heme protein, mitochondrial", "gene_name": "CYT1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MFSNLSKRWAQRTLSKSFYSTATGAASKSGKLTQKLVTAGVAAAGITASTLLYADSLTAEAMTAAEHGLHAPAYAWSHNGPFETFDHASIRRGYQVYREVCAACHSLDRVAWRTLVGVSHTNEEVRNMAEEFEYDDEPDEQGNPKKRPGKLSDYIPGPYPNEQAARAANQGALPPDLSLIVKARHGGCDYIFSLLTGYPDEPPAGVALPPGSNYNPYFPGGSIAMARVLFDDMVEYEDGTPATTSQMAKDVTTFLNWCAEPEHDERKRLGLKTVIILSSLYLLSIWVKKFKWAGIKTRKFVFNPPKPRK", "length": 309 }, "evidence": [ { "id": "RGD:1306597", "url": "https://alliancegenome.org/gene/RGD:1306597#orthology", "database": "AGR" }, { "id": "MGI:1913695", "url": "https://alliancegenome.org/gene/MGI:1913695#orthology", "database": "AGR" }, { "id": "HGNC:2579", "url": "https://alliancegenome.org/gene/HGNC:2579#orthology", "database": "AGR" }, { "id": "FB:FBgn0035600", "url": "https://alliancegenome.org/gene/FB:FBgn0035600#orthology", "database": "AGR" }, { "id": "SGD:S000005591", "url": "https://alliancegenome.org/gene/SGD:S000005591#orthology", "database": "AGR" }, { "id": "Q9VRL0", "url": "https://omabrowser.org/oma/group/Q9VRL0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P08574-1", "protein_name": "Cytochrome c1, heme protein, mitochondrial", "gene_name": "CYC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAAASLRGVVLGPRGAGLPGARARGLLCSARPGQLPLRTPQAVALSSKSGLSRGRKVMLSALGMLAAGGAGLAMALHSAVSASDLELHPPSYPWSHRGLLSSLDHTSIRRGFQVYKQVCASCHSMDFVAYRHLVGVCYTEDEAKELAAEVEVQDGPNEDGEMFMRPGKLFDYFPKPYPNSEAARAANNGALPPDLSYIVRARHGGEDYVFSLLTGYCEPPTGVSLREGLYFNPYFPGQAIAMAPPIYTDVLEFDDGTPATMSQIAKDVCTFLRWASEPEHDHRKRMGLKMLMMMALLVPLVYTIKRHKWSVLKSRKLAYRPPK", "length": 325 }, "evidence": [ { "id": "RGD:1306597", "url": "https://alliancegenome.org/gene/RGD:1306597#orthology", "database": "AGR" }, { "id": "MGI:1913695", "url": "https://alliancegenome.org/gene/MGI:1913695#orthology", "database": "AGR" }, { "id": "HGNC:2579", "url": "https://alliancegenome.org/gene/HGNC:2579#orthology", "database": "AGR" }, { "id": "FB:FBgn0035600", "url": "https://alliancegenome.org/gene/FB:FBgn0035600#orthology", "database": "AGR" }, { "id": "SGD:S000005591", "url": "https://alliancegenome.org/gene/SGD:S000005591#orthology", "database": "AGR" }, { "id": "Q9VRL0", "url": "https://omabrowser.org/oma/group/Q9VRL0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q54D07-1", "protein_name": "Cytochrome c1, heme protein, mitochondrial", "gene_name": "cyc1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFSQKLLANGKLLSKLAIVSGVVGTATAITTSTTLLSDDFVQPTSYPWEHRFPWQSYDHAAIRRGHQVYTQVCSTCHSLNLISYRHLANVAYTPEELKAMAADTTVMDGPDSEGDMFERKGQVTDFHPKPYPNSNAARFANNGALPPDLSLVIKARGAHEDYVFSLLTGYCEPPAGVRVVGGQYFNPYFPGTKIAMAPPLADGMVEYDDGTDNSMSQMAKDVSTFLCWASEPEHDDRKKLGMKVLLGVSIIALPLFYWKRLKWSVIKTRKISFKD", "length": 275 }, "evidence": [ { "id": "Q9VRL0", "url": "https://omabrowser.org/oma/group/Q9VRL0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9D0M3-1", "protein_name": "Cytochrome c1, heme protein, mitochondrial", "gene_name": "Cyc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAAASLRRTVLGPRGVGLPGASAPGLLGGARSRQLPLRTPQAVSLSSKSGPSRGRKVMLSALGMLAAGGAGLAVALHSAVSASDLELHPPSYPWSHRGLLSSLDHTSIRRGFQVYKQVCSSCHSMDYVAYRHLVGVCYTEEEAKALAEEVEVQDGPNDDGEMFMRPGKLSDYFPKPYPNPEAARAANNGALPPDLSYIVRARHGGEDYVFSLLTGYCEPPTGVSLREGLYFNPYFPGQAIGMAPPIYTEVLEYDDGTPATMSQVAKDVATFLRWASEPEHDHRKRMGLKMLLMMGLLLPLTYAMKRHKWSVLKSRKLAYRPPK", "length": 325 }, "evidence": [ { "id": "RGD:1306597", "url": "https://alliancegenome.org/gene/RGD:1306597#orthology", "database": "AGR" }, { "id": "MGI:1913695", "url": "https://alliancegenome.org/gene/MGI:1913695#orthology", "database": "AGR" }, { "id": "HGNC:2579", "url": "https://alliancegenome.org/gene/HGNC:2579#orthology", "database": "AGR" }, { "id": "FB:FBgn0035600", "url": "https://alliancegenome.org/gene/FB:FBgn0035600#orthology", "database": "AGR" }, { "id": "SGD:S000005591", "url": "https://alliancegenome.org/gene/SGD:S000005591#orthology", "database": "AGR" }, { "id": "Q9VRL0", "url": "https://omabrowser.org/oma/group/Q9VRL0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9FKS5-1", "protein_name": "Cytochrome c1 2, heme protein, mitochondrial", "gene_name": "CYC1-2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVGGGVIRQLLRRKLHSQSVATPVLSWLSSKKANEDAGSAGLRAFALMGAGITGLLSFSTVASADEAEHGLECPNYPWPHEGILSSYDHASIRRGHQVYQQVCASCHSMSLISYRDLVGVAYTEEEAKAMAAEIEVVDGPNDEGEMFTRPGKLSDRLPEPYSNESAARFANGGAYPPDLSLVTKARHNGQNYVFALLTGYRDPPAGISIREGLHYNPYFPGGAIAMPKMLNDEAVEYEDGTPATEAQMGKDVVSFLSWAAEPEMEERKLMGFKWIFLLSLALLQAAYYRRLKWSVLKSRKLVLDVVN", "length": 307 }, "evidence": [ { "id": "Q9VRL0", "url": "https://omabrowser.org/oma/group/Q9VRL0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VAM8-1", "protein_name": "Cytochrome c1, heme protein, mitochondrial", "gene_name": "Cyt-c1L", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MANKFRSLNSKLFQLAMSGIQRTSVRPRISFPGRGSGFTGNRKLLGALGALTGTAGLLIYALETSVDASSDCVHPAHQHWNHKGLLSALDKESVRRGYTVYKEVCSSCHSLQYMAYRNLVGVCMTEAEAKAEAEAITVRDGPNEEGEYYERPGKLSDHFPSPYANEEAARSANNGSYPPDLSYIVSARKGGEDYVFSLLTGYCDPPAGFALRDGLYFNPYFSGGAIAMGKVVDNEVVSFEDPNVPASAAQIAKDVCVFLKWTSEPETDERRLLLIKVTLISTFLIGISYYIKRFKWSTLKSRKIFFIPELEAQAKREAEEAAKAARKAKEQECNKCENQNEKKD", "length": 344 }, "evidence": [ { "id": "RGD:1306597", "url": "https://alliancegenome.org/gene/RGD:1306597#orthology", "database": "AGR" }, { "id": "MGI:1913695", "url": "https://alliancegenome.org/gene/MGI:1913695#orthology", "database": "AGR" }, { "id": "HGNC:2579", "url": "https://alliancegenome.org/gene/HGNC:2579#orthology", "database": "AGR" }, { "id": "SGD:S000005591", "url": "https://alliancegenome.org/gene/SGD:S000005591#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9VRL0", "url": "https://www.uniprot.org/uniprotkb/Q9VRL0" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q9VRL0", "url": "https://www.uniprot.org/uniprotkb/Q9VRL0" } ], "pmid": "" }, { "name": "respiratory chain complex III", "id": "GO:0045275", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045275", "evidence": [ { "database": "UniProtKB", "id": "Q9VRL0", "url": "https://www.uniprot.org/uniprotkb/Q9VRL0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VRL0", "url": "https://www.uniprot.org/uniprotkb/Q9VRL0" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "Q9VRL0", "url": "https://www.uniprot.org/uniprotkb/Q9VRL0" } ], "pmid": "" }, { "name": "quinol-cytochrome-c reductase activity", "id": "GO:0008121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008121", "evidence": [ { "database": "UniProtKB", "id": "Q9VRL0", "url": "https://www.uniprot.org/uniprotkb/Q9VRL0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mitochondrial electron transport, ubiquinol to cytochrome c", "id": "GO:0006122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006122", "evidence": [ { "database": "UniProtKB", "id": "Q9VRL0", "url": "https://www.uniprot.org/uniprotkb/Q9VRL0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 27, "end_pos": 29, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VRL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VRL0" }, { "id": "PS51007", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51007" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cytochrome c", "eco_id": "ECO_0000259", "start_pos": 89, "end_pos": 185, "start_aa": "Gln", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 27, "end_pos": 29 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VRL8-1", "uniprot_ac": "Q9VRL8", "uniprot_id": "Q9VRL8_DROME", "mass": { "chemical_mass": 35625.0, "monoisotopic_mass": 35625.0 }, "refseq": { "ac": "NP_647966", "name": "blanks", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647966" }, "gene_names": [ { "name": "blanks", "type": "recommended", "evidence": [ { "id": "Q9VRL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VRL8" } ] }, { "name": "Blanks", "type": "synonym", "evidence": [ { "id": "NP_647966", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647966" }, { "id": "Q9VRL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VRL8" } ] }, { "name": "CG10630", "type": "synonym", "evidence": [ { "id": "NP_647966", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647966" }, { "id": "Q9VRL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VRL8" } ] }, { "name": "Dmel\\CG10630", "type": "synonym", "evidence": [ { "id": "NP_647966", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647966" }, { "id": "Q9VRL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VRL8" } ] }, { "name": "Dmel_CG10630", "type": "synonym", "evidence": [ { "id": "Q9VRL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VRL8" } ] }, { "name": "blanks", "type": "synonym", "evidence": [ { "id": "NP_647966", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647966" } ] }, { "name": "lump", "type": "synonym", "evidence": [ { "id": "NP_647966", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647966" }, { "id": "Q9VRL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VRL8" } ] } ], "protein_names": [ { "name": "Blanks", "type": "synonym", "evidence": [ { "id": "Q9VRL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VRL8/entry#names_and_taxonomy" } ] }, { "name": "CG10630-PA", "type": "synonym", "evidence": [ { "id": "NP_647966", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647966" } ] }, { "name": "blanks-PA", "type": "synonym", "evidence": [ { "id": "NP_647966", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647966" } ] }, { "name": "blanks", "type": "synonym", "evidence": [ { "id": "NP_647966", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647966" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VRL8", "url": "https://www.uniprot.org/uniprotkb/Q9VRL8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "blanks", "url": "https://www.uniprot.org/uniprotkb/Q9VRL8", "locus": { "chromosome": "3L", "start_pos": 5497523, "end_pos": 5498958, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0035608", "url": "https://www.ensemblgenomes.org/id/FBgn0035608" } ] } } ], "crossref": [ { "id": "FB:FBgn0035608", "url": "https://alliancegenome.org/gene/FB:FBgn0035608", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0035608", "url": "https://bgee.org/?page=gene&gene_id=FBgn0035608", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0035608", "url": "https://flybase.org/reports/FBgn0035608", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "38620", "url": "https://www.ncbi.nlm.nih.gov/gene/38620", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR051247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG10630", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG10630", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ARVDNCE", "url": "https://omabrowser.org/oma/group/ARVDNCE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VRL8", "url": "https://www.orthodb.org/?gene=Q9VRL8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46205", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46205", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46205:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46205:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "R-DME-203927", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-203927", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-426486", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-426486", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-9833482", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9833482", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_647966", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647966", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VRL8", "url": "https://www.uniprot.org/uniprotkb/Q9VRL8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VRL8-1", "url": "https://www.uniprot.org/uniprotkb/Q9VRL8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAKQLLAESCAKVDILEMKKALIPNPSAEEDAVAVIPLADNLKKTAMGGENKSDEKGTVSSEPKALSDQITSSMRVTKNKIADDKSSDVITDDATNGRKKQKKNKKAKIRPLTMPVTSKDALMVLNELKGVTVDNMQIKRDHEGKIMARVVVNSKKYEAEGSSVNSARNAACEKALQEILTTKMKAVLDGPGKSLESDEDDILEKMASYAIHKLGEEWKTDDIDVATLYNDLKNKQTSVVEPKKPLPETWKNMHPCMVLNYMRPQCTFIVSGGTGTNQNNTFSMSVCVDNCEFNAEGPSKKAARYKLSALVCNKLFGTDYPQK", "length": 324, "header": "tr|Q9VRL8-1|Q9VRL8_DROME Isoform 1 of Blanks OS=Drosophila melanogaster OX=7227 GN=blanks PE=1 SV=1 CANONICAL=Q9VRL8-1" }, "isoforms": [ { "isoform_ac": "Q9VRL8-1", "url": "https://www.uniprot.org/uniprotkb/Q9VRL8/entry#Q9VRL8-1", "sequence": { "sequence": "MEAKQLLAESCAKVDILEMKKALIPNPSAEEDAVAVIPLADNLKKTAMGGENKSDEKGTVSSEPKALSDQITSSMRVTKNKIADDKSSDVITDDATNGRKKQKKNKKAKIRPLTMPVTSKDALMVLNELKGVTVDNMQIKRDHEGKIMARVVVNSKKYEAEGSSVNSARNAACEKALQEILTTKMKAVLDGPGKSLESDEDDILEKMASYAIHKLGEEWKTDDIDVATLYNDLKNKQTSVVEPKKPLPETWKNMHPCMVLNYMRPQCTFIVSGGTGTNQNNTFSMSVCVDNCEFNAEGPSKKAARYKLSALVCNKLFGTDYPQK", "length": 324, "header": "tr|Q9VRL8-1|Q9VRL8_DROME Isoform 1 of Blanks OS=Drosophila melanogaster OX=7227 GN=blanks PE=1 SV=1 CANONICAL=Q9VRL8-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "15952742", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/15952742" }, { "id": "Q9VRL8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9VRL8" } ], "filter_code": "00000000000000000000.0000000.00000001000000.1000000.0100000000.110100100001111011.10000.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_reported_with_glycan" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VRL8", "url": "https://www.uniprot.org/uniprotkb/Q9VRL8" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VRL8", "url": "https://www.uniprot.org/uniprotkb/Q9VRL8" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": 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mildform of hypophosphatasia characterized by osteomalacia, chondrocalcinosis, osteoarthropathy, stress fractures duringmiddle age, and dental anomalies." }, { "id": "MONDO:1010154", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:1010154", "name": "adult hypophosphatasia", "description": "" }, { "id": "MONDO:1010154", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:1010154", "name": "hypophosphatasia of adults", "description": "" }, { "id": "MIM:146300", "resource": "MIM", "url": "https://www.omim.org/entry/146300", "name": "Hypophosphatasia", "description": "Hypophosphatasia" } ], "unlinked_id_list": [], "evidence": [ { "id": "0110913", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110913" } ] }, { "disease_id": "DOID:0110914", "recommended_name": { "id": "DOID:0110914", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110914", "name": "infantile hypophosphatasia", "description": "A hypophosphatasia that has_material_basis_in homozygous or compound heterozygosity mutation in the gene encoding tissue-nonspecific alkaline phosphatase (ALPL) on chromosome 1p36." }, "synonyms": [ { "id": "DOID:0110914", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110914", "name": "phosphoethanolaminuria", "description": "" }, { "id": "DOID:0110914", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110914", "name": "HOPS", "description": "" }, { "id": "DOID:0110914", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110914", "name": "HPPI", "description": "" }, { "id": "MONDO:1010169", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:1010169", "name": "infantile hypophosphatasia", "description": "Infantile hypophosphatasia (I-HPP) is a very rare, severe form of hypophosphatasia characterized by infantile rickets without elevated serum alkaline phosphatase (ALP) activity and a wide range of clinical manifestations due to hypomineralization." }, { "id": "MONDO:1010169", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:1010169", "name": "infantile hypophosphatasia", "description": "" }, { "id": "MIM:241500", "resource": "MIM", "url": "https://www.omim.org/entry/241500", "name": "Hypophosphatasia, infantile", "description": "Hypophosphatasia, infantile" } ], "unlinked_id_list": [], "evidence": [ { "id": "0110914", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110914" } ] }, { "disease_id": "DOID:0110915", "recommended_name": { "id": "DOID:0110915", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110915", "name": "childhood hypophosphatasia", "description": "A hypophosphatasia that has_material_basis_in an autosomal recessive mutation of the ALPL gene on chromosome 1p36.12." }, "synonyms": [ { "id": "MONDO:1010168", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:1010168", "name": "childhood hypophosphatasia", "description": "Childhood-onset hypophosphatasia is a rare, mildform of hypophosphatasia characterized by onset after six months of age and widely variable clinical features from low bone mineral density for age, to unexplained fractures,skeletal deformities,and rickets with short stature and waddling gait." }, { "id": "MONDO:1010168", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:1010168", "name": "childhood hypophosphatasia", "description": "" }, { "id": "MONDO:1010168", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:1010168", "name": "hypophosphatasia of childhood", "description": "" }, { "id": "MONDO:1010168", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:1010168", "name": "pediatric hypophosphatasia", "description": "" }, { "id": "MONDO:1010168", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:1010168", "name": "childhood-onset hypophosphatasia", "description": "" }, { "id": "MIM:241510", "resource": "MIM", "url": "https://www.omim.org/entry/241510", "name": "Hypophosphatasia, childhood", "description": "Hypophosphatasia, childhood" } ], "unlinked_id_list": [], "evidence": [ { "id": "0110915", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110915" } ] }, { "disease_id": "DOID:13809", "recommended_name": { "id": "DOID:13809", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13809", "name": "familial combined hyperlipidemia", "description": "" }, "synonyms": [ { "id": "DOID:13809", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13809", "name": "familial multiple lipoprotein-type hyperlipidemia", "description": "" }, { "id": "DOID:13809", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13809", "name": "mixed hyperlipidaemia", "description": "" }, { "id": "DOID:13809", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13809", "name": "type IIb hyperlipoproteinemia", "description": "" }, { "id": "DOID:13809", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13809", "name": "hyperbetalipoproteinemia with prebetalipoproteinemia", "description": "" }, { "id": "MONDO:0007759", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007759", "name": "hyperlipidemia, familial combined, LPL related", "description": "" }, { "id": "MONDO:0007759", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007759", "name": "combined hyperlipidemia, familial", "description": "" }, { "id": "MONDO:0007759", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007759", "name": "FCHL", "description": "" }, { "id": "MONDO:0007759", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007759", "name": "hyperlipidemia, familial combined", "description": "" }, { "id": "MIM:144250", "resource": "MIM", "url": "https://www.omim.org/entry/144250", "name": "Hyperlipidemia, familial combined, 3", "description": "Hyperlipidemia, familial combined, 3" } ], "unlinked_id_list": [], "evidence": [ { "id": "13809", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13809" } ] }, { "disease_id": "DOID:14213", "recommended_name": { "id": "DOID:14213", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14213", "name": "hypophosphatasia", "description": "A syndrome characterized by disruption of mineralization of bones and teeth that has_material_basis_in mutation in the ALPL gene on chromosome 1p36.12." }, "synonyms": [ { "id": "DOID:14213", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14213", "name": "deficiency of alkaline phosphatase", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "14213", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14213" } ] }, { "disease_id": "DOID:2349", "recommended_name": { "id": "DOID:2349", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2349", "name": "arteriosclerosis", "description": "An artery disease that is characterized by a thickening and hardening of arterial walls in the arteries." }, "synonyms": [ { "id": "DOID:2349", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2349", "name": "Arteriosclerotic vascular disease", "description": "" } ], "unlinked_id_list": [ "DOID:2348" ], "evidence": [ { "id": "2349", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2349" } ] }, { "disease_id": "DOID:4676", "recommended_name": { "id": "DOID:4676", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4676", "name": "uremia", "description": "" }, "synonyms": [ { "id": "DOID:4676", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4676", "name": "UREMIA OF renal ORIGIN", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "4676", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4676" } ] }, { "disease_id": "DOID:8577", "recommended_name": { "id": "DOID:8577", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8577", "name": "ulcerative colitis", "description": "A colitis that is predominantly confined to the mucosa located_in colon and includes characteristic ulcers, or open sores." }, "synonyms": [ { "id": "DOID:8577", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8577", "name": "Left-sided ulcerative colitis", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "8577", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8577" } ] }, { "disease_id": "DOID:8719", "recommended_name": { "id": "DOID:8719", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8719", "name": "in situ carcinoma", "description": "A carcinoma that is an early development defined by the absence of invasion of surrounding tissues." }, "synonyms": [], "unlinked_id_list": [ "DOID:9108" ], "evidence": [ { "id": "8719", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8719" } ] }, { "disease_id": "DOID:8778", "recommended_name": { "id": "DOID:8778", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8778", "name": "Crohn's disease", "description": "An intestinal disease that involves inflammation located_in intestine." }, "synonyms": [ { "id": "DOID:8778", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8778", "name": "Crohn disease", "description": "" }, { "id": "DOID:8778", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8778", "name": "Crohn's disease of colon", "description": "" }, { "id": "DOID:8778", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8778", "name": "Crohn's disease of large bowel", "description": "" }, { "id": "DOID:8778", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8778", "name": "Granulomatous Colitis", "description": "" }, { "id": "DOID:8778", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8778", "name": "Pediatric Crohn's disease", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "8778", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8778" } ] }, { "disease_id": "DOID:9452", "recommended_name": { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "steatotic liver disease", "description": "A lipid storage disease characterized by the accumulation of large vacuoles of triglyceride fat in at least 5% of hepatocytes." }, "synonyms": [ { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "Fatty change of liver", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "Steatosis of liver", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "alcoholic fatty liver", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "hepatic lipidosis", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "SLD", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "fatty liver disease", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "hepatic steatosis", "description": "" }, { "id": "MONDO:0009220", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009220", "name": "visceral steatosis, congenital", "description": "" }, { "id": "MONDO:0009220", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009220", "name": "visceral steatosis, congenital", "description": "" }, { "id": "MONDO:0009220", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009220", "name": "fatal neonatal hepatic steatosis", "description": "" }, { "id": "MONDO:0009220", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009220", "name": "visceral steatosis", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "9452", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9452" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VRM8", "url": "https://www.uniprot.org/uniprotkb/Q9VRM8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Alp10", "url": "https://www.uniprot.org/uniprotkb/Q9VRM8", "locus": { "chromosome": "3L", "start_pos": 5592741, "end_pos": 5595272, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0035619", "url": "https://www.ensemblgenomes.org/id/FBgn0035619" } ] } } ], "crossref": [ { "id": "FB:FBgn0035619", "url": "https://alliancegenome.org/gene/FB:FBgn0035619", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0035619", "url": "https://bgee.org/?page=gene&gene_id=FBgn0035619", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16012", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16012", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0035619", "url": "https://flybase.org/reports/FBgn0035619", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "38632", "url": "https://www.ncbi.nlm.nih.gov/gene/38632", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001952", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001952", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017850", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017850", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG10592", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG10592", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GYPYRRQ", "url": "https://omabrowser.org/oma/group/GYPYRRQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VRM8", "url": "https://www.orthodb.org/?gene=Q9VRM8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11596", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11596", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11596:SF91", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11596:SF91", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00245", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00245", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-1483166", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1483166", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-6811438", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6811438", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-8935690", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8935690", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_647976", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647976", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VRM8", "url": "https://www.uniprot.org/uniprotkb/Q9VRM8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VRM8-1", "url": "https://www.uniprot.org/uniprotkb/Q9VRM8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVKSCLILCFFALLVIQARSDLADDQEHAQHPRLQSSRDFEALDEELDTRFWHDKAQSILADKLAGHKKLNENRAKNVILFLGDGMSVHTIAATRAFMGDSNKQVFFEKFPYLGLSKTYAVNERTPDSANTATAYLTGVKANYGTIGVNAQVQRGDCVTNSSSHVQSIGQWAQEAGKWAGLVTTARVTHASPAGVYAHVSERNWEHDGEIISSKCSPDVNTDIARQLVEWPVGQELRVIMGGGRSYFRDQSQHDETGVSGLRTDGRDLISDWREIKKQQGAEGKYVWSLKGLKETDISKTDYLLGLFDTSHLPYHGDRRRTHYEDAEPSLSDMTEAAIKMLSKNEEGYFLFVESGRIDMAHHATKAMKALEDTEEFAAAVELARKMTDEEDTLIVVTSDHSHTMSINGYPYRRQNILSLAPNLADDELPFTILSYANGPGFDDTYSTKDGRIDLSHADTTSAEFEFQATVPLSSETHGAEDVGVFASGPFEHLFTGNYEQSAIPAMMAYAANIGPFAKDKINEQ", "length": 524, "header": "tr|Q9VRM8-1|Q9VRM8_DROME Isoform 1 of alkaline phosphatase OS=Drosophila melanogaster OX=7227 GN=Alp10 PE=1 SV=1 CANONICAL=Q9VRM8-1" }, "isoforms": [ { "isoform_ac": "Q9VRM8-1", "url": "https://www.uniprot.org/uniprotkb/Q9VRM8/entry#Q9VRM8-1", "sequence": { "sequence": "MVKSCLILCFFALLVIQARSDLADDQEHAQHPRLQSSRDFEALDEELDTRFWHDKAQSILADKLAGHKKLNENRAKNVILFLGDGMSVHTIAATRAFMGDSNKQVFFEKFPYLGLSKTYAVNERTPDSANTATAYLTGVKANYGTIGVNAQVQRGDCVTNSSSHVQSIGQWAQEAGKWAGLVTTARVTHASPAGVYAHVSERNWEHDGEIISSKCSPDVNTDIARQLVEWPVGQELRVIMGGGRSYFRDQSQHDETGVSGLRTDGRDLISDWREIKKQQGAEGKYVWSLKGLKETDISKTDYLLGLFDTSHLPYHGDRRRTHYEDAEPSLSDMTEAAIKMLSKNEEGYFLFVESGRIDMAHHATKAMKALEDTEEFAAAVELARKMTDEEDTLIVVTSDHSHTMSINGYPYRRQNILSLAPNLADDELPFTILSYANGPGFDDTYSTKDGRIDLSHADTTSAEFEFQATVPLSSETHGAEDVGVFASGPFEHLFTGNYEQSAIPAMMAYAANIGPFAKDKINEQ", "length": 524, "header": "tr|Q9VRM8-1|Q9VRM8_DROME Isoform 1 of alkaline phosphatase OS=Drosophila melanogaster OX=7227 GN=Alp10 PE=1 SV=1 CANONICAL=Q9VRM8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM8", "url": "https://www.uniprot.org/uniprotkb/Q9VRM8" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM8", "url": "https://www.uniprot.org/uniprotkb/Q9VRM8" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM8", "url": "https://www.uniprot.org/uniprotkb/Q9VRM8" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM8", "url": "https://www.uniprot.org/uniprotkb/Q9VRM8" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM8", "url": "https://www.uniprot.org/uniprotkb/Q9VRM8" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM8", "url": "https://www.uniprot.org/uniprotkb/Q9VRM8" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM8", "url": "https://www.uniprot.org/uniprotkb/Q9VRM8" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM8", "url": "https://www.uniprot.org/uniprotkb/Q9VRM8" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM8", "url": "https://www.uniprot.org/uniprotkb/Q9VRM8" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM8", "url": "https://www.uniprot.org/uniprotkb/Q9VRM8" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM8", "url": "https://www.uniprot.org/uniprotkb/Q9VRM8" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG10592", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG10592", "resource": "KEGG Pathway" }, { "id": "R-DME-1483166", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1483166", "resource": "Reactome", "description": "Synthesis of PA" }, { "id": "R-DME-6811438", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6811438", "resource": "Reactome", "description": "Intra-Golgi traffic" }, { "id": "R-DME-8935690", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8935690", "resource": "Reactome", "description": "Digestion" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0L8R7-1", "protein_name": "Alkaline phosphatase", "gene_name": "Akp3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPTLQFQRGIEASKMTQQVKVPATQAESNTWSTHKVEEENPAFWNQKAADALNVAKKLQPIQTSAKNLIIFLGDGMGVPTVTATRILKGQLEGNLGPETPLAMDHFPYMALSKTYSVDRQVPDSASTATAYLCGVKTNYKTIGVSAAARFDQCNTTFGNEVLSVMYRAKKAGKSVGVVTTTRVQHASPAGTYVHTVNRNWYGDADMPASALQEGCKDIATQLVSNMDINVILGGGRKYMFPAGTPDPEYPNDVNETGTRLDGKNLVQEWLSKHQGSQYVWNRQELIQKSLDPSVTYLMGLFEPVDTKFEIQRDPLMDPSLKDMTEAALHVLSRNPKGFYLFVEGGRIDRGHHLGTAYLALTEAVMFDSAIERASQLTSEQDTLTIVTADHSHVFSFGGYTLRGTSIFGLAPLNALDGKPYTSILYGNGPGYVGTGERPNVTDAESHDPSYQQQAAVPVKSETHGGEDVAIFARGPQAHLLHGVQEQNYIAHVMAFAGCLEPYTDCGLAPPADENRPTTPVQNSTTTTTTTTTTTTTRVQNSASSLGPATGPLALALLAKALMLLLGAPADF", "length": 571 }, "evidence": [ { "id": "MGI:87984", "url": "https://alliancegenome.org/gene/MGI:87984#orthology", "database": "AGR" }, { "id": "HGNC:441", "url": "https://alliancegenome.org/gene/HGNC:441#orthology", "database": "AGR" }, { "id": "HGNC:437", "url": "https://alliancegenome.org/gene/HGNC:437#orthology", "database": "AGR" }, { "id": "FB:FBgn0035619", "url": "https://alliancegenome.org/gene/FB:FBgn0035619#orthology", "database": "AGR" }, { "id": "RGD:621650", "url": "https://alliancegenome.org/gene/RGD:621650#orthology", "database": "AGR" }, { "id": "SGD:S000002889", "url": "https://alliancegenome.org/gene/SGD:S000002889#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ADM6-1", "protein_name": "Alkaline phosphatase", "gene_name": "Alpp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAMWGACLLLLGLSLQMSLSLVPVEEENPAFWNRKAAEALEAAKKLQPIQTSANNLIILMGDGMGVSTVTATRILKGQQQGHLGPETPLAMDRFPHMALSKTYNTDKQVPDSAGTGTAFLCGVKTNMKVIGLSAAARFNQCNTTWGNEVVSVMHRAKKAGKSVGVVTTTSVQHASPAGTYAHTVNRNWYSDAHMSTAALQEGCKDIAMQLISNTDIDVILGGGRKFMFPKGTPDQEYPTDPQQAGTRLDGRNLVQEWLAKHQGAQYVWNRTELIQASLNRSVTHLMGLFEPNDMKYNIDRDPTQDPSLAEMTEVAVHMLSRNPKGFYLFVEGGRIDHGHHEAIAYRALTEAVMFDSAVDKADKLTSEKDTMIIVTADHSHVFSFGGYTQREASIFGLAPFKAGDGKSFTSILYGNGPGYKLNNGIRADVTEEESSNPTYQQQAAVPLSSETHSGEDVAIFARGPQAHLVHGVQEQNYIAHVMAFAGCLEPYTDCGLAPPAGRSSAVSPGYISTLLCLLAGTMLMLMVSAEP", "length": 531 }, "evidence": [ { "id": "MGI:108009", "url": "https://alliancegenome.org/gene/MGI:108009#orthology", "database": "AGR" }, { "id": "FB:FBgn0035619", "url": "https://alliancegenome.org/gene/FB:FBgn0035619#orthology", "database": "AGR" }, { "id": "RGD:2325055", "url": "https://alliancegenome.org/gene/RGD:2325055#orthology", "database": "AGR" }, { "id": "SGD:S000002889", "url": "https://alliancegenome.org/gene/SGD:S000002889#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M8U7-1", "protein_name": "Alkaline phosphatase", "gene_name": "Alpg", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQGAWVLLLLLLGLRLQLSFGVIPVEEENPAFWNQKAKEALDVAKKLKPIRTSAKNLIIFLGDGMGVPTVTATRILKGQLGGHLGPETPLAMDHFPFTALSKTYNVDRQVPDSAGTATAYLCGVKANYKTIGVSAAARFNQCNSTFGNEVFSVMHRAKKAGKSVGVVTTTSVQHASPAGTYAHTVNCDWYSDAHMATAALQEGCKDIAMQLISNMDIDVILGGGRKFMFPKGTPDPEYSGNRAQSGTRLDGQNLVQKWLAKHQGARYVWNRTELIQASQDSAVTHLMGLFEPNDMKYDIYRDPTQDPSLAEMTEVAVHLLSRNPKGFYLFVEGGHIDHGHHESIAYRALTEAVMFDSAVDKANKLTSEKDTMILVTADHSHVFSFGGYVPRGTSIFGLGASFNALDGRPFTSILYGNGPGYKLEKGTRPDVTDKESRDPKYRQQAAVPLSSETHSGEDVAIFARGPQAHLVHGVQEQNYIAHVMAFAGCLEPYTDCGLAPPAGRSSAVSPGYISTLLCLLAGTMLMLLVSAEP", "length": 533 }, "evidence": [ { "id": "HGNC:441", "url": "https://alliancegenome.org/gene/HGNC:441#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1Q5B5-1", "protein_name": "Alkaline phosphatase", "gene_name": "alpl", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWECGCFLVLWSELSVVWHPWNVKIRKRRLIDNKMKVVQLLILSCLVWEGKTKVQFPEQEKRPDYWRDFAQRSLKDALKLQELNKNIAKNIILFLGDGMGVPTVTAARILKGQLSGQNGEETQLEMDKFPHVALSKTYNTNAQVPDSAGTATAFLCGVKANEGTVGVSAAAVRSQCNTTQGNEVTSILKWAKDAGKSVGIVTTTRVNHATPSAAYAHCVDRDWYSDADMPNEALQSGCKDIARQLFENIPDINVIMGGGRRSMYPKNTPDVEYPGDKKQNGTRKDGRNLVGEWIDRVKEKRGFYVWNKKDLLSLNPNNVDYLLGLFEPADLNYELERNTENDPSLTEMVDVAIKILKKNERGFFLLVEGGRIDHGHHEGKAKQALHEAVEMDRAITRAGLLTSEYDTLTVVTADHSHVFSFGGYTPRGNSIFGLAPTLSDVDQKPFTAILYGNGPGFKLVNGARENVSTVDYQQNNYQAQSAVPLRMETHGGEDVAIFSKGPMAHLLHGVQEQHYIPHVMAYAACIGQNKDHCRTNSGSSSYFSHISPALLFPLLVKWLLC", "length": 561 }, "evidence": [ { "id": "MGI:87983", "url": "https://alliancegenome.org/gene/MGI:87983#orthology", "database": "AGR" }, { "id": "HGNC:438", "url": "https://alliancegenome.org/gene/HGNC:438#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F8VPQ6-1", "protein_name": "Alkaline phosphatase", "gene_name": "Alpi", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQGDWVLLLFLGLRIHLSFGIIPAEEENPAFWNKKAAEALDAAKKLQPIQTSAKNLIIFLGDGMGVPTVTATRILKGQLEGHLGPETPLAMDLFPYMALSKTYNVDRQVPDSAGTATAYLCGVKANYKTIGLSAAARLDQCNTTFGNEVFSVMYRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRNWYSDAEMPASALQDGCKDIATQLISNMDIDVILGGGRKFMFPKGTPDPEYPSDSNQSGTRLDDQNLVQTWLSKHQGARYVWNRSELIQASQDPAVTHLMGLFEPTEMKYDANRNPSVDPSLAEMTEVAVRMLSRNPQGFYLFVEGGRIDQGHHAGTAYLALTEAVMFDSAIEKASQLTNEKDTLILITADHSHVFAFGGYTLRGTSIFGLAPLKALDDKSYTSILYGNGPGYELKSGNRPNVTEAQSVDPNYKQQAAVPLSSETHGGEDVAIFARGPQAHLVHGVQEQNYIAHVMAFAGCLEPYTDCGLAPPAGQSPVITPGQATTTNNAAGQATTTNNAAGQATVLLSLQLLVSMLLLVGTAMVVS", "length": 554 }, "evidence": [ { "id": "RGD:2099", "url": "https://alliancegenome.org/gene/RGD:2099#orthology", "database": "AGR" }, { "id": "MGI:1924018", "url": "https://alliancegenome.org/gene/MGI:1924018#orthology", "database": "AGR" }, { "id": "HGNC:441", "url": "https://alliancegenome.org/gene/HGNC:441#orthology", "database": "AGR" }, { "id": "HGNC:437", "url": "https://alliancegenome.org/gene/HGNC:437#orthology", "database": "AGR" }, { "id": "FB:FBgn0035619", "url": "https://alliancegenome.org/gene/FB:FBgn0035619#orthology", "database": "AGR" }, { "id": "SGD:S000002889", "url": "https://alliancegenome.org/gene/SGD:S000002889#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M9PD70-1", "protein_name": "alkaline phosphatase", "gene_name": "Alp1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRALRFFAALALQLTACSSQYKYGPEQSWDLDSISELKSKEFWFHDAQRTLYNKLSTPPNQYRAKNVIFFLGDGMSVPTVTAGRIFDGQLRGVVGERNRLEFEKFNYVGLSKTYCVNKQVADSACTASAYLSGIKANYLTIGVTADVELNDCRGSRLPQNRLSSIAAWALKGSKSAGLVTTTRVTHASPAGVYAHTSNRDFESDYDVTKLGQNPGNCPDIAQQLIDGDVGKRLRVVMGGGTIKFLPNTTNDVFGNKGQRLDNRNLIEEWQQTKPGNARVVFSRTDLLNNDAQNTDFLLGLFNASHLAYHMDDSIDTPTLPEMTAAAINVLSRDPNGYFLFVEGGRIDHAHHETKAKKALDETVQFSDAVRKARQLTNPWDTLIVVSADHGHTVTISGYPDVNNSIVGLNSELSNVDQLPYTSISYANGPAYERFYKSTDGVVERVDLRNLDFSKPDAIYPHGVPMTEETHGGGDVAVYAHVVEYLLQGPWSHLFTGVYEQSTLPHLMGFASCLGPGITYCDLQPKARYSP", "length": 530 }, "evidence": [ { "id": "RGD:2099", "url": "https://alliancegenome.org/gene/RGD:2099#orthology", "database": "AGR" }, { "id": "MGI:1924018", "url": "https://alliancegenome.org/gene/MGI:1924018#orthology", "database": "AGR" }, { "id": "MGI:87984", "url": "https://alliancegenome.org/gene/MGI:87984#orthology", "database": "AGR" }, { "id": "MGI:108009", "url": "https://alliancegenome.org/gene/MGI:108009#orthology", "database": "AGR" }, { "id": "MGI:87983", "url": "https://alliancegenome.org/gene/MGI:87983#orthology", "database": "AGR" }, { "id": "HGNC:438", "url": "https://alliancegenome.org/gene/HGNC:438#orthology", "database": "AGR" }, { "id": "HGNC:441", "url": "https://alliancegenome.org/gene/HGNC:441#orthology", "database": "AGR" }, { "id": "HGNC:437", "url": "https://alliancegenome.org/gene/HGNC:437#orthology", "database": "AGR" }, { "id": "RGD:2325055", "url": "https://alliancegenome.org/gene/RGD:2325055#orthology", "database": "AGR" }, { "id": "RGD:621650", "url": "https://alliancegenome.org/gene/RGD:621650#orthology", "database": "AGR" }, { "id": "RGD:2100", "url": "https://alliancegenome.org/gene/RGD:2100#orthology", "database": "AGR" }, { "id": "SGD:S000002889", "url": "https://alliancegenome.org/gene/SGD:S000002889#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P05186-1", "protein_name": "Alkaline phosphatase, tissue-nonspecific isozyme", "gene_name": "ALPL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MISPFLVLAIGTCLTNSLVPEKEKDPKYWRDQAQETLKYALELQKLNTNVAKNVIMFLGDGMGVSTVTAARILKGQLHHNPGEETRLEMDKFPFVALSKTYNTNAQVPDSAGTATAYLCGVKANEGTVGVSAATERSRCNTTQGNEVTSILRWAKDAGKSVGIVTTTRVNHATPSAAYAHSADRDWYSDNEMPPEALSQGCKDIAYQLMHNIRDIDVIMGGGRKYMYPKNKTDVEYESDEKARGTRLDGLDLVDTWKSFKPRYKHSHFIWNRTELLTLDPHNVDYLLGLFEPGDMQYELNRNNVTDPSLSEMVVVAIQILRKNPKGFFLLVEGGRIDHGHHEGKAKQALHEAVEMDRAIGQAGSLTSSEDTLTVVTADHSHVFTFGGYTPRGNSIFGLAPMLSDTDKKPFTAILYGNGPGYKVVGGERENVSMVDYAHNNYQAQSAVPLRHETHGGEDVAVFSKGPMAHLLHGVHEQNYVPHVMAYAACIGANLGHCAPASSAGSLAAGPLLLALALYPLSVLF", "length": 524 }, "evidence": [ { "id": "MGI:87983", "url": "https://alliancegenome.org/gene/MGI:87983#orthology", "database": "AGR" }, { "id": "HGNC:438", "url": "https://alliancegenome.org/gene/HGNC:438#orthology", "database": "AGR" }, { "id": "FB:FBgn0035619", "url": "https://alliancegenome.org/gene/FB:FBgn0035619#orthology", "database": "AGR" }, { "id": "RGD:2100", "url": "https://alliancegenome.org/gene/RGD:2100#orthology", "database": "AGR" }, { "id": "SGD:S000002889", "url": "https://alliancegenome.org/gene/SGD:S000002889#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P05187-1", "protein_name": "Alkaline phosphatase, placental type", "gene_name": "ALPP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLGPCMLLLLLLLGLRLQLSLGIIPVEEENPDFWNREAAEALGAAKKLQPAQTAAKNLIIFLGDGMGVSTVTAARILKGQKKDKLGPEIPLAMDRFPYVALSKTYNVDKHVPDSGATATAYLCGVKGNFQTIGLSAAARFNQCNTTRGNEVISVMNRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRNWYSDADVPASARQEGCQDIATQLISNMDIDVILGGGRKYMFRMGTPDPEYPDDYSQGGTRLDGKNLVQEWLAKRQGARYVWNRTELMQASLDPSVTHLMGLFEPGDMKYEIHRDSTLDPSLMEMTEAALRLLSRNPRGFFLFVEGGRIDHGHHESRAYRALTETIMFDDAIERAGQLTSEEDTLSLVTADHSHVFSFGGYPLRGSSIFGLAPGKARDRKAYTVLLYGNGPGYVLKDGARPDVTESESGSPEYRQQSAVPLDEETHAGEDVAVFARGPQAHLVHGVQEQTFIAHVMAFAACLEPYTACDLAPPAGTTDAAHPGRSVVPALLPLLAGTLLLLETATAP", "length": 535 }, "evidence": [ { "id": "RGD:2099", "url": "https://alliancegenome.org/gene/RGD:2099#orthology", "database": "AGR" }, { "id": "MGI:1924018", "url": "https://alliancegenome.org/gene/MGI:1924018#orthology", "database": "AGR" }, { "id": "MGI:87984", "url": "https://alliancegenome.org/gene/MGI:87984#orthology", "database": "AGR" }, { "id": "MGI:108009", "url": "https://alliancegenome.org/gene/MGI:108009#orthology", "database": "AGR" }, { "id": "RGD:2325055", "url": "https://alliancegenome.org/gene/RGD:2325055#orthology", "database": "AGR" }, { "id": "RGD:621650", "url": "https://alliancegenome.org/gene/RGD:621650#orthology", "database": "AGR" }, { "id": "SGD:S000002889", "url": "https://alliancegenome.org/gene/SGD:S000002889#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P08289-1", "protein_name": "Alkaline phosphatase, tissue-nonspecific isozyme", "gene_name": "Alpl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MILPFLVLAIGTCLTNSFVPEKEKDPSYWRQQAQETLKNALKLQKLNTNVAKNIIMFLGDGMGVSTVTAARILKGQLHHNTGEETRLEMDKFPFVALSKTYNTNAQVPDSAGTATAYLCGVKANEGTVGVSAATERTRCNTTQGNEVTSILRWAKDAGKSVGIVTTTRVNHATPSAAYAHSADRDWYSDNEMPPEALSQGCKDIAYQLMHNIKDIDVIMGGGRKYMYPKNRTDVEYELDEKARGTRLDGLDLISIWKSFKPRHKHSHYVWNRTELLALDPSRVDYLLGLFEPGDMQYELNRNNLTDPSLSEMVEVALRILTKNPKGFFLLVEGGRIDHGHHEGKAKQALHEAVEMDEAIGKAGTMTSQKDTLTVVTADHSHVFTFGGYTPRGNSIFGLAPMVSDTDKKPFTAILYGNGPGYKVVDGERENVSMVDYAHNNYQAQSAVPLRHETHGGEDVAVFAKGPMAHLLHGVHEQNYIPHVMAYASCIGANLDHCAWASSASSPSPGALLLPLALFPLRTLF", "length": 524 }, "evidence": [ { "id": "MGI:87983", "url": "https://alliancegenome.org/gene/MGI:87983#orthology", "database": "AGR" }, { "id": "HGNC:438", "url": "https://alliancegenome.org/gene/HGNC:438#orthology", "database": "AGR" }, { "id": "FB:FBgn0035619", "url": "https://alliancegenome.org/gene/FB:FBgn0035619#orthology", "database": "AGR" }, { "id": "RGD:2100", "url": "https://alliancegenome.org/gene/RGD:2100#orthology", "database": "AGR" }, { "id": "SGD:S000002889", "url": "https://alliancegenome.org/gene/SGD:S000002889#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P09242-1", "protein_name": "Alkaline phosphatase, tissue-nonspecific isozyme", "gene_name": "Alpl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MISPFLVLAIGTCLTNSFVPEKERDPSYWRQQAQETLKNALKLQKLNTNVAKNVIMFLGDGMGVSTVTAARILKGQLHHNTGEETRLEMDKFPFVALSKTYNTNAQVPDSAGTATAYLCGVKANEGTVGVSAATERTRCNTTQGNEVTSILRWAKDAGKSVGIVTTTRVNHATPSAAYAHSADRDWYSDNEMPPEALSQGCKDIAYQLMHNIKDIDVIMGGGRKYMYPKNRTDVEYELDEKARGTRLDGLDLISIWKSFKPRHKHSHYVWNRTELLALDPSRVDYLLGLFEPGDMQYELNRNNLTDPSLSEMVEVALRILTKNLKGFFLLVEGGRIDHGHHEGKAKQALHEAVEMDQAIGKAGAMTSQKDTLTVVTADHSHVFTFGGYTPRGNSIFGLAPMVSDTDKKPFTAILYGNGPGYKVVDGERENVSMVDYAHNNYQAQSAVPLRHETHGGEDVAVFAKGPMAHLLHGVHEQNYIPHVMAYASCIGANLDHCAWAGSGSAPSPGALLLPLAVLSLRTLF", "length": 524 }, "evidence": [ { "id": "MGI:87983", "url": "https://alliancegenome.org/gene/MGI:87983#orthology", "database": "AGR" }, { "id": "HGNC:438", "url": "https://alliancegenome.org/gene/HGNC:438#orthology", "database": "AGR" }, { "id": "FB:FBgn0035619", "url": "https://alliancegenome.org/gene/FB:FBgn0035619#orthology", "database": "AGR" }, { "id": "RGD:2100", "url": "https://alliancegenome.org/gene/RGD:2100#orthology", "database": "AGR" }, { "id": "SGD:S000002889", "url": "https://alliancegenome.org/gene/SGD:S000002889#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P09923-1", "protein_name": "Intestinal-type alkaline phosphatase", "gene_name": "ALPI", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQGPWVLLLLGLRLQLSLGVIPAEEENPAFWNRQAAEALDAAKKLQPIQKVAKNLILFLGDGLGVPTVTATRILKGQKNGKLGPETPLAMDRFPYLALSKTYNVDRQVPDSAATATAYLCGVKANFQTIGLSAAARFNQCNTTRGNEVISVMNRAKQAGKSVGVVTTTRVQHASPAGTYAHTVNRNWYSDADMPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPADASQNGIRLDGKNLVQEWLAKHQGAWYVWNRTELMQASLDQSVTHLMGLFEPGDTKYEIHRDPTLDPSLMEMTEAALRLLSRNPRGFYLFVEGGRIDHGHHEGVAYQALTEAVMFDDAIERAGQLTSEEDTLTLVTADHSHVFSFGGYTLRGSSIFGLAPSKAQDSKAYTSILYGNGPGYVFNSGVRPDVNESESGSPDYQQQAAVPLSSETHGGEDVAVFARGPQAHLVHGVQEQSFVAHVMAFAACLEPYTACDLAPPACTTDAAHPVAASLPLLAGTLLLLGASAAP", "length": 528 }, "evidence": [ { "id": "RGD:2099", "url": "https://alliancegenome.org/gene/RGD:2099#orthology", "database": "AGR" }, { "id": "MGI:1924018", "url": "https://alliancegenome.org/gene/MGI:1924018#orthology", "database": "AGR" }, { "id": "MGI:87984", "url": "https://alliancegenome.org/gene/MGI:87984#orthology", "database": "AGR" }, { "id": "MGI:108009", "url": "https://alliancegenome.org/gene/MGI:108009#orthology", "database": "AGR" }, { "id": "HGNC:437", "url": "https://alliancegenome.org/gene/HGNC:437#orthology", "database": "AGR" }, { "id": "FB:FBgn0035619", "url": "https://alliancegenome.org/gene/FB:FBgn0035619#orthology", "database": "AGR" }, { "id": "RGD:621650", "url": "https://alliancegenome.org/gene/RGD:621650#orthology", "database": "AGR" }, { "id": "SGD:S000002889", "url": "https://alliancegenome.org/gene/SGD:S000002889#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P10696-1", "protein_name": "Alkaline phosphatase, germ cell type", "gene_name": "ALPG", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQGPWVLLLLGLRLQLSLGIIPVEEENPDFWNRQAAEALGAAKKLQPAQTAAKNLIIFLGDGMGVSTVTAARILKGQKKDKLGPETFLAMDRFPYVALSKTYSVDKHVPDSGATATAYLCGVKGNFQTIGLSAAARFNQCNTTRGNEVISVMNRAKKAGKSVGVVTTTRVQHASPAGAYAHTVNRNWYSDADVPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPDDYSQGGTRLDGKNLVQEWLAKHQGARYVWNRTELLQASLDPSVTHLMGLFEPGDMKYEIHRDSTLDPSLMEMTEAALLLLSRNPRGFFLFVEGGRIDHGHHESRAYRALTETIMFDDAIERAGQLTSEEDTLSLVTADHSHVFSFGGYPLRGSSIFGLAPGKARDRKAYTVLLYGNGPGYVLKDGARPDVTESESGSPEYRQQSAVPLDGETHAGEDVAVFARGPQAHLVHGVQEQTFIAHVMAFAACLEPYTACDLAPRAGTTDAAHPGPSVVPALLPLLAGTLLLLGTATAP", "length": 532 }, "evidence": [ { "id": "RGD:2099", "url": "https://alliancegenome.org/gene/RGD:2099#orthology", "database": "AGR" }, { "id": "MGI:1924018", "url": "https://alliancegenome.org/gene/MGI:1924018#orthology", "database": "AGR" }, { "id": "MGI:87984", "url": "https://alliancegenome.org/gene/MGI:87984#orthology", "database": "AGR" }, { "id": "MGI:108009", "url": "https://alliancegenome.org/gene/MGI:108009#orthology", "database": "AGR" }, { "id": "HGNC:441", "url": "https://alliancegenome.org/gene/HGNC:441#orthology", "database": "AGR" }, { "id": "FB:FBgn0035619", "url": "https://alliancegenome.org/gene/FB:FBgn0035619#orthology", "database": "AGR" }, { "id": "RGD:621650", "url": "https://alliancegenome.org/gene/RGD:621650#orthology", "database": "AGR" }, { "id": "SGD:S000002889", "url": "https://alliancegenome.org/gene/SGD:S000002889#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P11491-1", "protein_name": "Repressible alkaline phosphatase", "gene_name": "PHO8", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MMTHTLPSEQTRLVPGSDSSSRPKKRRISKRSKIIVSTVVCIGLLLVLVQLAFPSSFALRSASHKKKNVIFFVTDGMGPASLSMARSFNQHVNDLPIDDILTLDEHFIGSSRTRSSDSLVTDSAAGATAFACALKSYNGAIGVDPHHRPCGTVLEAAKLAGYLTGLVVTTRITDATPASFSSHVDYRWQEDLIATHQLGEYPLGRVVDLLMGGGRSHFYPQGEKASPYGHHGARKDGRDLIDEAQSNGWQYVGDRKNFDSLLKSHGENVTLPFLGLFADNDIPFEIDRDEKEYPSLKEQVKVALGALEKASNEDKDSNGFFLMVEGSRIDHAGHQNDPASQVREVLAFDEAFQYVLEFAENSDTETVLVSTSDHETGGLVTSRQVTASYPQYVWYPQVLANATHSGEFLKRKLVDFVHEHKGASSKIENFIKHEILEKDLGIYDYTDSDLETLIHLDDNANAIQDKLNDMVSFRAQIGWTTHGHSAVDVNIYAYANKKATWSYVLNNLQGNHENTEVGQFLENFLELNLNEVTDLIRDTKHTSDFDATEIASEVQHYDEYYHELTN", "length": 566 }, "evidence": [ { "id": "RGD:2099", "url": "https://alliancegenome.org/gene/RGD:2099#orthology", "database": "AGR" }, { "id": "MGI:1924018", "url": "https://alliancegenome.org/gene/MGI:1924018#orthology", "database": "AGR" }, { "id": "MGI:87984", "url": "https://alliancegenome.org/gene/MGI:87984#orthology", "database": "AGR" }, { "id": "MGI:108009", "url": "https://alliancegenome.org/gene/MGI:108009#orthology", "database": "AGR" }, { "id": "MGI:87983", "url": "https://alliancegenome.org/gene/MGI:87983#orthology", "database": "AGR" }, { "id": "HGNC:438", "url": "https://alliancegenome.org/gene/HGNC:438#orthology", "database": "AGR" }, { "id": "HGNC:441", "url": "https://alliancegenome.org/gene/HGNC:441#orthology", "database": "AGR" }, { "id": "HGNC:437", "url": "https://alliancegenome.org/gene/HGNC:437#orthology", "database": "AGR" }, { "id": "FB:FBgn0035619", "url": "https://alliancegenome.org/gene/FB:FBgn0035619#orthology", "database": "AGR" }, { "id": "RGD:2325055", "url": "https://alliancegenome.org/gene/RGD:2325055#orthology", "database": "AGR" }, { "id": "RGD:621650", "url": "https://alliancegenome.org/gene/RGD:621650#orthology", "database": "AGR" }, { "id": "RGD:2100", "url": "https://alliancegenome.org/gene/RGD:2100#orthology", "database": "AGR" }, { "id": "SGD:S000002889", "url": "https://alliancegenome.org/gene/SGD:S000002889#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P15693-1", "protein_name": "Intestinal-type alkaline phosphatase 1", "gene_name": "Alpi", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQGDWVLLLLLGLRIHLSFGVIPVEEENPVFWNQKAKEALDVAKKLQPIQTSAKNLILFLGDGMGVPTVTATRILKGQLGGHLGPETPLAMDHFPFTALSKTYNVDRQVPDSAGTATAYLCGVKANYKTIGVSAAARFNQCNSTFGNEVFSVMHRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRDWYSDADMPSSALQEGCKDIATQLISNMDIDVILGGGRKFMFPKGTPDPEYPGDSDQSGVRLDSRNLVEEWLAKYQGTRYVWNREQLMQASQDPAVTRLMGLFEPTEMKYDVNRNASADPSLAEMTEVAVRLLSRNPQGFYLFVEGGRIDQGHHAGTAYLALTEAVMFDSAIEKASQLTNEKDTLTLITADHSHVFAFGGYTLRGTSIFGLAPLNAQDGKSYTSILYGNGPGYVLNSGNRPNVTDAESGDVNYKQQAAVPLSSETHGGEDVAIFARGPQAHLVHGVQEQNYIAHVMAFAGCLEPYTDCGLAPPADENRPTTPVQNSAITMNNVLLSLQLLVSMLLLVGTALVVS", "length": 540 }, "evidence": [ { "id": "RGD:2099", "url": "https://alliancegenome.org/gene/RGD:2099#orthology", "database": "AGR" }, { "id": "MGI:1924018", "url": "https://alliancegenome.org/gene/MGI:1924018#orthology", "database": "AGR" }, { "id": "HGNC:441", "url": "https://alliancegenome.org/gene/HGNC:441#orthology", "database": "AGR" }, { "id": "HGNC:437", "url": "https://alliancegenome.org/gene/HGNC:437#orthology", "database": "AGR" }, { "id": "FB:FBgn0035619", "url": "https://alliancegenome.org/gene/FB:FBgn0035619#orthology", "database": "AGR" }, { "id": "SGD:S000002889", "url": "https://alliancegenome.org/gene/SGD:S000002889#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24822-1", "protein_name": "Intestinal-type alkaline phosphatase", "gene_name": "Iap", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQGPWVLLLLGLRLQLSLSVIPVEEENPAFWNKKAAEALDAAKKLQPIQTSAKNLIIFLGDGMGVPTVTATRILKGQLEGHLGPETPLAMDRFPYMALSKTYSVDRQVPDSASTATAYLCGVKTNYKTIGLSAAARFDQCNTTFGNEVFSVMYRAKKAGKSVGVVTTTRVQHASPSGTYVHTVNRNWYGDADMPASALREGCKDIATQLISNMDINVILGGGRKYMFPAGTPDPEYPNDANETGTRLDGRNLVQEWLSKHQGSQYVWNREQLIQKAQDPSVTYLMGLFEPVDTKFDIQRDPLMDPSLKDMTETAVKVLSRNPKGFYLFVEGGRIDRGHHLGTAYLALTEAVMFDLAIERASQLTSERDTLTIVTADHSHVFSFGGYTLRGTSIFGLAPLNALDGKPYTSILYGNGPGYVGTGERPNVTAAESSGSSYRRQAAVPVKSETHGGEDVAIFARGPQAHLVHGVQEQNYIAHVMASAGCLEPYTDCGLAPPADESQTTTTTRQTTITTTTTTTTTTTTPVHNSARSLGPATAPLALALLAGMLMLLLGAPAES", "length": 559 }, "evidence": [ { "id": "MGI:87984", "url": "https://alliancegenome.org/gene/MGI:87984#orthology", "database": "AGR" }, { "id": "HGNC:441", "url": "https://alliancegenome.org/gene/HGNC:441#orthology", "database": "AGR" }, { "id": "HGNC:437", "url": "https://alliancegenome.org/gene/HGNC:437#orthology", "database": "AGR" }, { "id": "FB:FBgn0035619", "url": "https://alliancegenome.org/gene/FB:FBgn0035619#orthology", "database": "AGR" }, { "id": "RGD:621650", "url": "https://alliancegenome.org/gene/RGD:621650#orthology", "database": "AGR" }, { "id": "SGD:S000002889", "url": "https://alliancegenome.org/gene/SGD:S000002889#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P24823-1", "protein_name": "Alkaline phosphatase, germ cell type", "gene_name": "Alpg", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWGACLLLLGLSLQVCPSVIPVEEENPAFWNRKAAEALDAAKKLKPIQTSAKNLVILMGDGMGVSTVTATRILKGQQQGHLGPETQLAMDRFPHMALSKTYNTDKQIPDSAGTGTAFLCGVKTNMKVIGLSAAARFNQCNTTWGNEVVSVMHRAKKAGKSVGVVTTTSVQHASPAGTYAHTVNRGWYSDAQMPASALQDGCKDISTQLISNMDIDVILGGGRKFMFPKGTPDQEYPTDTKQAGTRLDGRNLVQEWLAKHQGARYVWNRSELIQASLNRSVTHLMGLFEPNDMKYEIHRDPAQDPSLAEMTEVAVRMLSRNPKGFYLFVEGGRIDHGHHETVAYRALTEAVMFDSAVDKADKLTSEQDTMILVTADHSHVFSFGGYTQRGASIFGLAPFKAEDGKSFTSILYGNGPGYKLHNGARADVTEEESSNPTYQQQAAVPLSSETHSGEDVAIFARGPQAHLVHGVQEQNYIAHVMAFAACLEPYTDCGLASPAGQSSAVSPGYMSTLLCLLAGKMLMLMAAAEP", "length": 529 }, "evidence": [ { "id": "MGI:108009", "url": "https://alliancegenome.org/gene/MGI:108009#orthology", "database": "AGR" }, { "id": "HGNC:441", "url": "https://alliancegenome.org/gene/HGNC:441#orthology", "database": "AGR" }, { "id": "HGNC:437", "url": "https://alliancegenome.org/gene/HGNC:437#orthology", "database": "AGR" }, { "id": "FB:FBgn0035619", "url": "https://alliancegenome.org/gene/FB:FBgn0035619#orthology", "database": "AGR" }, { "id": "RGD:2325055", "url": "https://alliancegenome.org/gene/RGD:2325055#orthology", "database": "AGR" }, { "id": "SGD:S000002889", "url": "https://alliancegenome.org/gene/SGD:S000002889#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q24238-1", "protein_name": "Alkaline phosphatase 4", "gene_name": "Alp4", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MHCLVILGFLLGSLVAFSWAGVTTQPPPLIRTLSAGGDIGPQFDVGKTKEPEDAEFWHNVGLRQLEKTIKQAQRVKEDSYQKKARNIIIFIGDGMGISTISAGRIYKGQYLKHGYGEEETLVFDDFPNTGMAKTYNVDKQVPDSAGTATAIFSGSKTHYGAIGMDATRSKKNGQQGRVQSVMEWAQKEGKRTGVVTTTRITHATPAATYAHIYDRDWECDTEVPAESVGFHVDIARQLVENAPGNRFNVILGGGMSPMGILNASEVKTTIFEGPTETICTRGDNRNLPAEWLAHHANDTVPPALVHNRKDLLNVNVKKVDHLMGLFRNNHITYSIAREAGEPSLQEMTETALGILERGDESNGFVLLVEGGRIDQGHHMNYARAALHELYEFDLAIQAAVNNTDPDETLILVTADHSHAVTFNGYALRGADILGTANSHEKNDPMFYETISYANGPGYWDHLANDSRPQNSSNMWMPLKHFTAEERAAPTYRHLATVPRKDETHGGEDVAVFAYGPGSSLIRGVFEQNYLAYVMSYAGCLGPAKDFDDSCEDHKDGQKDRPLDKPNPKRNGATVVGASLIPILTAATAAILRGRGL", "length": 596 }, "evidence": [ { "id": "RGD:2099", "url": "https://alliancegenome.org/gene/RGD:2099#orthology", "database": "AGR" }, { "id": "MGI:1924018", "url": "https://alliancegenome.org/gene/MGI:1924018#orthology", "database": "AGR" }, { "id": "MGI:87984", "url": "https://alliancegenome.org/gene/MGI:87984#orthology", "database": "AGR" }, { "id": "MGI:108009", "url": "https://alliancegenome.org/gene/MGI:108009#orthology", "database": "AGR" }, { "id": "MGI:87983", "url": "https://alliancegenome.org/gene/MGI:87983#orthology", "database": "AGR" }, { "id": "HGNC:437", "url": "https://alliancegenome.org/gene/HGNC:437#orthology", "database": "AGR" }, { "id": "RGD:2325055", "url": "https://alliancegenome.org/gene/RGD:2325055#orthology", "database": "AGR" }, { "id": "RGD:621650", "url": "https://alliancegenome.org/gene/RGD:621650#orthology", "database": "AGR" }, { "id": "RGD:2100", "url": "https://alliancegenome.org/gene/RGD:2100#orthology", "database": "AGR" }, { "id": "SGD:S000002889", "url": "https://alliancegenome.org/gene/SGD:S000002889#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VDG4-1", "protein_name": "Alkaline phosphatase", "gene_name": "Alp5", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFRLLNALLIAIVLVAHPAWSAPECGRTPEECREHRMHPDMPEPERHGKAFRVVDGEDTNAYWRQQGVQFVQQKLASEPNKRQAKNVILFLGDGMGVTTTSAARNLLGGEEKSLSFENFPFTGLSKTYSVDKIVPDSACTATAYLCGVKGQEGTIGVNGQVPRTDCKVMLDESTHVDSIAKWAMEAGKWAGLVTTTRVTHASPSGVYAHIAERDWENDAEVATDCGAGSGINDIAYQLARGEVGSKLKVIMGGGRKHFVDSSLESWGKRTDGLNLIDEFKSASENNVYVTTAAELAAVDVTKTDRLLGLFNDDHLQYLMETTTESSQPTLEQMTRKAIEYMSQNEQGYFLFIEGGRIDQAHHINQARMALNETIEFSKAIAAAQELTSEDDTLLVVTADHSHVFTYAGYSYRGSDVFGKTPVNGHDGKPYMVLSYANGPSYENFYDAETMERKDPTTVVKGDHDDEFPSGVPIDMDSHGGDDVPVYALGPWAHLFTGVYEQSTIPHMMAYASCLGDGHTMCK", "length": 522 }, "evidence": [ { "id": "RGD:2099", "url": "https://alliancegenome.org/gene/RGD:2099#orthology", "database": "AGR" }, { "id": "MGI:1924018", "url": "https://alliancegenome.org/gene/MGI:1924018#orthology", "database": "AGR" }, { "id": "MGI:87984", "url": "https://alliancegenome.org/gene/MGI:87984#orthology", "database": "AGR" }, { "id": "MGI:108009", "url": "https://alliancegenome.org/gene/MGI:108009#orthology", "database": "AGR" }, { "id": "MGI:87983", "url": "https://alliancegenome.org/gene/MGI:87983#orthology", "database": "AGR" }, { "id": "HGNC:438", "url": "https://alliancegenome.org/gene/HGNC:438#orthology", "database": "AGR" }, { "id": "HGNC:441", "url": "https://alliancegenome.org/gene/HGNC:441#orthology", "database": "AGR" }, { "id": "HGNC:437", "url": "https://alliancegenome.org/gene/HGNC:437#orthology", "database": "AGR" }, { "id": "RGD:2325055", "url": "https://alliancegenome.org/gene/RGD:2325055#orthology", "database": "AGR" }, { "id": "RGD:621650", "url": "https://alliancegenome.org/gene/RGD:621650#orthology", "database": "AGR" }, { "id": "RGD:2100", "url": "https://alliancegenome.org/gene/RGD:2100#orthology", "database": "AGR" }, { "id": "SGD:S000002889", "url": "https://alliancegenome.org/gene/SGD:S000002889#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VHD0-1", "protein_name": "Alkaline phosphatase", "gene_name": "phu", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRLQLFFFLGLSVLVSGGESSHDAERRMHPVFSLMGTGSNPIGGGRYKRAMPQIVFDAVRSEERYAEYWQGLAAQTLDQQLESKLRLNTQLARNVMLFIGDGMSIPTITAGRVYLGGEEKQFAFEQFPYVGLSKTYCANMQVADSACTATAYLGGVKANYGTIGVSAAVQFKDCQAQAQAAHHVSSIAAWAQKQGMATGLVTTTSVTHASPAGVYAHLANRNWENDAEVVGDNGDPDLCPDAAAQLINSPVGQKLNVIMGGGRENFLPKGVTDSSGAPGRRLDGRNLIDEWKNQHTNSAQYVENRRELLNLSNHTSRVLGLFAPYHMAYHLDASPAEQPTLEEMVQSAMEILERQSAGRGYFLFVEGGRIDHGHHDTLALRAIDETAEFDKAVRFARSHTSTDDTLIVVSSDHSHTMSLAGYSSRKNDIFGINDGQLAADDLPYATLSYANGPGYDSNYLREGGAVRRKNLRAINMKNKDFMFPSTVPLESETHGGDDVAVFASGPYAQLFTGVFEQHFIPHALGYASCLSDRNMCVDGGVARRPR", "length": 546 }, "evidence": [ { "id": "RGD:2099", "url": "https://alliancegenome.org/gene/RGD:2099#orthology", "database": "AGR" }, { "id": "MGI:1924018", "url": "https://alliancegenome.org/gene/MGI:1924018#orthology", "database": "AGR" }, { "id": "MGI:87984", "url": "https://alliancegenome.org/gene/MGI:87984#orthology", "database": "AGR" }, { "id": "MGI:108009", "url": "https://alliancegenome.org/gene/MGI:108009#orthology", "database": "AGR" }, { "id": "MGI:87983", "url": "https://alliancegenome.org/gene/MGI:87983#orthology", "database": "AGR" }, { "id": "HGNC:438", "url": "https://alliancegenome.org/gene/HGNC:438#orthology", "database": "AGR" }, { "id": "HGNC:441", "url": "https://alliancegenome.org/gene/HGNC:441#orthology", "database": "AGR" }, { "id": "HGNC:437", "url": "https://alliancegenome.org/gene/HGNC:437#orthology", "database": "AGR" }, { "id": "RGD:2325055", "url": "https://alliancegenome.org/gene/RGD:2325055#orthology", "database": "AGR" }, { "id": "RGD:621650", "url": "https://alliancegenome.org/gene/RGD:621650#orthology", "database": "AGR" }, { "id": "RGD:2100", "url": "https://alliancegenome.org/gene/RGD:2100#orthology", "database": "AGR" }, { "id": "SGD:S000002889", "url": "https://alliancegenome.org/gene/SGD:S000002889#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VIW9-1", "protein_name": "alkaline phosphatase", "gene_name": "Alp12", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEKRSGTPINSQKFRKLSDVDMTEVQLNNLDDSSAKETVEIGSFQGNDQSNPVQHTKWFRSRLFLISVVFSALLITAMCIGFVVHYGMSGDVGDMETVSYWPVDLPKEQKEWYDQGIDELQKAVSRQFNRRRAKNVILFVGDGMGPNTVTAARILGVKEEGLLRWEQFPDMGLLKTYCADKQVPDSFSTATALFGGVKVNYETGGVDANVPLGNCSASLKEDHHVQTILKWAQVDGMRTGFVTTTRVTHATPAALYAHVPDRRWECESGMPAEAQGQGCMDIARQLIEQPTGQSINVIMGGGRQMLVSDVTGSAADPLDTWAGQSKDGRDLIRDWRLKKADEGVSHAVVQNNRELWNLNGQDVDYVLGIFANGHLMYDHERDRSDAGMPSLSNMTLKALEVLGNSDKGFLLVVEAGLIDQAHHRGNARKALSEVLELNAAVESTLSFLKSSDRLDETLVIVTADHSHSLTINGHPDRGSSILGLAGNSKTEGTPYTTLTYGTSYQGFQVDPQTQSRKDPTADDITAWEYTQQAAINTDENLHGGSDVTIHADGAMSYLFHGVHEQSYVAHAISYALRIGRFRDSSIAETLAELTPI", "length": 596 }, "evidence": [ { "id": "RGD:2099", "url": "https://alliancegenome.org/gene/RGD:2099#orthology", "database": "AGR" }, { "id": "MGI:1924018", "url": "https://alliancegenome.org/gene/MGI:1924018#orthology", "database": "AGR" }, { "id": "MGI:87984", "url": "https://alliancegenome.org/gene/MGI:87984#orthology", "database": "AGR" }, { "id": "MGI:108009", "url": "https://alliancegenome.org/gene/MGI:108009#orthology", "database": "AGR" }, { "id": "MGI:87983", "url": "https://alliancegenome.org/gene/MGI:87983#orthology", "database": "AGR" }, { "id": "HGNC:438", "url": "https://alliancegenome.org/gene/HGNC:438#orthology", "database": "AGR" }, { "id": "HGNC:441", "url": "https://alliancegenome.org/gene/HGNC:441#orthology", "database": "AGR" }, { "id": "HGNC:437", "url": "https://alliancegenome.org/gene/HGNC:437#orthology", "database": "AGR" }, { "id": "RGD:2325055", "url": "https://alliancegenome.org/gene/RGD:2325055#orthology", "database": "AGR" }, { "id": "RGD:621650", "url": "https://alliancegenome.org/gene/RGD:621650#orthology", "database": "AGR" }, { "id": "RGD:2100", "url": "https://alliancegenome.org/gene/RGD:2100#orthology", "database": "AGR" }, { "id": "SGD:S000002889", "url": "https://alliancegenome.org/gene/SGD:S000002889#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VRM9-1", "protein_name": "alkaline phosphatase", "gene_name": "Alp9", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLSLKFWIRLGLLTVVWGAAVPGRAPVDEERMHPHLPTSPRLRTISGEETQEFWHSASKKLIREKLEFVRNTKKAKNIILFLGDGMGLATLAAARSYIGGEELKLSFEEFPFTGLSKTYSVDKIVPDSACTSTSYLCGVKANYGTIGVNAHVKRGDCAAMANETNHVFSLGKWAMDAGKAAGLVTTTRVTHASPSGVYAHVADREWENNAVLEEACGELSDGLQDIAVQLIHGEVGSKLKVMLGGGKRSFYSPEHYDKGRRTDGRNLVEEFEALDAGNTFVKTQKKLLNVNATETGRLLGLFSKSHMHYHLEQLADPDNNEPTLEEMTQKAIEVLETEEQGYFLFVEGGKIDISHHETMARIALDETAELSKAVKKAREMTNPEETLIVVTSDHSHTFSVSGYQPRGSDIFGAAKANGKDGKPYLALSYANGKSFQDYYNTETHERVDPTSLPTIGDFDQLFPAMVPLESETHGGEDVGVFASGPWAHLFTGVYEQNTIPHMMAFAACVGDGLTACD", "length": 517 }, "evidence": [ { "id": "RGD:2099", "url": "https://alliancegenome.org/gene/RGD:2099#orthology", "database": "AGR" }, { "id": "MGI:1924018", "url": "https://alliancegenome.org/gene/MGI:1924018#orthology", "database": "AGR" }, { "id": "MGI:87984", "url": "https://alliancegenome.org/gene/MGI:87984#orthology", "database": "AGR" }, { "id": "MGI:108009", "url": "https://alliancegenome.org/gene/MGI:108009#orthology", "database": "AGR" }, { "id": "MGI:87983", "url": "https://alliancegenome.org/gene/MGI:87983#orthology", "database": "AGR" }, { "id": "HGNC:438", "url": "https://alliancegenome.org/gene/HGNC:438#orthology", "database": "AGR" }, { "id": "HGNC:441", "url": "https://alliancegenome.org/gene/HGNC:441#orthology", "database": "AGR" }, { "id": "HGNC:437", "url": "https://alliancegenome.org/gene/HGNC:437#orthology", "database": "AGR" }, { "id": "RGD:2325055", "url": "https://alliancegenome.org/gene/RGD:2325055#orthology", "database": "AGR" }, { "id": "RGD:621650", "url": "https://alliancegenome.org/gene/RGD:621650#orthology", "database": "AGR" }, { "id": "RGD:2100", "url": "https://alliancegenome.org/gene/RGD:2100#orthology", "database": "AGR" }, { "id": "SGD:S000002889", "url": "https://alliancegenome.org/gene/SGD:S000002889#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VXS8-1", "protein_name": "alkaline phosphatase", "gene_name": "Alp11", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLLQLRRLAILFLLHALIPILALSVPMVEQVQPADELLSSHWLRQAQSQLRERLARTKDSIADVRQAKNVVMLLGDGLSITTLTAARILKGQRRGGRGEDAQLAVEQFPFSGLSKTYCIDEQTPDSACTATAYFGGVKTHSGTVGQSGSGERVDSVLQWAQRAGKATGVVTTTRLTDASPAGAYAHVSRRGEELEIARQLVEEEPGRNLNVILGGGLGKFADERRDGKDLLAQWRESNPNGCFSRSLKELRNCTDATGTLLGIFSDSHMSYHLAASKELPRLCDMAAAAIEKLERKSQEDGNGYFVFIEGGRIDHGHHETRVGYALDEMVEFDAAVETVIQMTDPRDTLVVVTADHSHTLSMSGYAKRGTPILGMDAQQRDVNGVPYSTLNYAIGKWQSLDKDGRRESPSKTLSPTSYTPSYIHGRKGVHSGEDVVVFAMGPQSHLFGGVMEQNLLPHIMGYAACLGNGLTLCNQDKDADMIA", "length": 483 }, "evidence": [ { "id": "RGD:2099", "url": "https://alliancegenome.org/gene/RGD:2099#orthology", "database": "AGR" }, { "id": "MGI:1924018", "url": "https://alliancegenome.org/gene/MGI:1924018#orthology", "database": "AGR" }, { "id": "MGI:87984", "url": "https://alliancegenome.org/gene/MGI:87984#orthology", "database": "AGR" }, { "id": "MGI:108009", "url": "https://alliancegenome.org/gene/MGI:108009#orthology", "database": "AGR" }, { "id": "MGI:87983", "url": "https://alliancegenome.org/gene/MGI:87983#orthology", "database": "AGR" }, { "id": "HGNC:438", "url": "https://alliancegenome.org/gene/HGNC:438#orthology", "database": "AGR" }, { "id": "HGNC:441", "url": "https://alliancegenome.org/gene/HGNC:441#orthology", "database": "AGR" }, { "id": "HGNC:437", "url": "https://alliancegenome.org/gene/HGNC:437#orthology", "database": "AGR" }, { "id": "RGD:2325055", "url": "https://alliancegenome.org/gene/RGD:2325055#orthology", "database": "AGR" }, { "id": "RGD:621650", "url": "https://alliancegenome.org/gene/RGD:621650#orthology", "database": "AGR" }, { "id": "RGD:2100", "url": "https://alliancegenome.org/gene/RGD:2100#orthology", "database": "AGR" }, { "id": "SGD:S000002889", "url": "https://alliancegenome.org/gene/SGD:S000002889#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W273-1", "protein_name": "Alkaline phosphatase", "gene_name": "Alp8", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGSSQRQLVLPILLLLALAGTALCGVQEVHNVLELTGQAANKLKFSTDVATEKYTPPEEMDPQYWYNIADEEITKRLQLPQPNSQKAKNIIMFLGDGMPLSTVAAARILKGQRQGNTGEESSLSFERFPYTGLSRTYCSNAQVPDSACTATAYLCGVKTNIVNIGVSAAVEYNNCTASQDPANRLTSIAEWAQNAGKSTGIVTTTTLTHASPSGAYAKTANRMWECDTDVTSYGVDANSCIDMATQLVTQTPGKNFEVMFGGGMGKFLPNSIVDSHGNPGERSDGVNLLSRWQGLHDGGVLVTNRNQLLKLNVSAVSSVIGLFQSKLMNFHLEADDTYQPTLSELTEVTIKKLSQNKEHGYFAFIEGGLIDYGNHYTKAGYALDEALEFEKAIQLARDMTDIEDTLIVVTADHGHAVSIAGYPGRGTPILGINQHDTDINGVQYSVLNYAAGPNQYLDENGQRIPLDDILGSDDAITPSYIPKDQGVHSGEDVGIFASGPQSHLFTGVMQQSTIPHLMAYAACIGSGKQVCDN", "length": 533 }, "evidence": [ { "id": "RGD:2099", "url": "https://alliancegenome.org/gene/RGD:2099#orthology", "database": "AGR" }, { "id": "MGI:1924018", "url": "https://alliancegenome.org/gene/MGI:1924018#orthology", "database": "AGR" }, { "id": "MGI:87984", "url": "https://alliancegenome.org/gene/MGI:87984#orthology", "database": "AGR" }, { "id": "MGI:108009", "url": "https://alliancegenome.org/gene/MGI:108009#orthology", "database": "AGR" }, { "id": "MGI:87983", "url": "https://alliancegenome.org/gene/MGI:87983#orthology", "database": "AGR" }, { "id": "HGNC:438", "url": "https://alliancegenome.org/gene/HGNC:438#orthology", "database": "AGR" }, { "id": "HGNC:441", "url": "https://alliancegenome.org/gene/HGNC:441#orthology", "database": "AGR" }, { "id": "HGNC:437", "url": "https://alliancegenome.org/gene/HGNC:437#orthology", "database": "AGR" }, { "id": "RGD:2325055", "url": "https://alliancegenome.org/gene/RGD:2325055#orthology", "database": "AGR" }, { "id": "RGD:621650", "url": "https://alliancegenome.org/gene/RGD:621650#orthology", "database": "AGR" }, { "id": "RGD:2100", "url": "https://alliancegenome.org/gene/RGD:2100#orthology", "database": "AGR" }, { "id": "SGD:S000002889", "url": "https://alliancegenome.org/gene/SGD:S000002889#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W274-1", "protein_name": "Alkaline phosphatase", "gene_name": "Alp2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MHISQRRCLYPIFLFLLAFVGTALGRVQEVHNVLELTGQKASKLRFSTDVATGKYTPPEEMDPQFWYKLADEEIAKRLQLPQPNSDRAKNVIMFLGDGMPISTVTAARILKGQRQGNTGEESSLSFEKFPYSGLSRTYCANAQVPDSACTATAYLCGVKTNIINIGVSAAVNFNNCTASQDPANRLTSIAEWAQNAGKSTGFVTTTTLTHASPSGAYAKTANRMWQSDTDVTSYGVDASTCVDMATQLVTQTPGKNFEVMFGGGMGKFLPKTTKDSHGKYGERSDGVNLLSRWQGLHDKGVLVTNRKQLLNLDVSAASSIIGTFQSGLMDFHMDADPTYQPTLSELTEVAIKKLSHNENGYFVFIEGGLIDYGNHYTQAGYALDEALEFEKAIQLAREMTNISDTLIVVTADHGHAVSIAGYPGRGTPILGLNQHDTDINGVKYSVLNYAAGPNQYLDEHGQRIPLDDILGPDDAISPSYIDKEIGVHSGEDVGIWASGPQSHLFTGVMQQSTIPHLMAYASCVGSGKQVCGSSGRKT", "length": 538 }, "evidence": [ { "id": "RGD:2099", "url": "https://alliancegenome.org/gene/RGD:2099#orthology", "database": "AGR" }, { "id": "MGI:1924018", "url": "https://alliancegenome.org/gene/MGI:1924018#orthology", "database": "AGR" }, { "id": "MGI:87984", "url": "https://alliancegenome.org/gene/MGI:87984#orthology", "database": "AGR" }, { "id": "MGI:108009", "url": "https://alliancegenome.org/gene/MGI:108009#orthology", "database": "AGR" }, { "id": "MGI:87983", "url": "https://alliancegenome.org/gene/MGI:87983#orthology", "database": "AGR" }, { "id": "HGNC:438", "url": "https://alliancegenome.org/gene/HGNC:438#orthology", "database": "AGR" }, { "id": "HGNC:441", "url": "https://alliancegenome.org/gene/HGNC:441#orthology", "database": "AGR" }, { "id": "HGNC:437", "url": "https://alliancegenome.org/gene/HGNC:437#orthology", "database": "AGR" }, { "id": "RGD:2325055", "url": "https://alliancegenome.org/gene/RGD:2325055#orthology", "database": "AGR" }, { "id": "RGD:621650", "url": "https://alliancegenome.org/gene/RGD:621650#orthology", "database": "AGR" }, { "id": "RGD:2100", "url": "https://alliancegenome.org/gene/RGD:2100#orthology", "database": "AGR" }, { "id": "SGD:S000002889", "url": "https://alliancegenome.org/gene/SGD:S000002889#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W275-1", "protein_name": "Alkaline phosphatase", "gene_name": "Alp7", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKTFVAISLVLCTLVATSLAASIDMPEIHNQFQLVGGSVSTAKTREGNLIDPNAMAKGKPGPEEEKNAQFWYDLAYEEIAKRLEQPQLDKRKAKNVILFLGDGMSLSTVAAARIHKGQLKGNTGEEDSLSFEKFPYTGLSRTYCSNAQVPDSACTATAYLCGVKTNIVALGITAAVSFNNCSGSEDPANQVDSIAAWAQAAGKATGIVTTTTLTHASPSGAYAKTTNRFFESDTDILTYGEGQNDPATCTDIATQLITQAPGKNFDVMLGGGIGKFLPNTITDPFNKKGERSDGVNLLSRWQGLHPGGVLAYNRNQLLSVNVSKITNLIGTFRSGVMSFNKMADPKEEPTLAEMTRKAIEVVSKRDGGYFLFVEGGLIDYGNHFNSPTYSLSETLQFEQAVQEALDITDPEETLIVVTSDHAHPLTISGYPGRGTPILGLNQDDTDVNGVKYATLNYAVGTNQYLDEHGQRIDLTDQIGAEDFIHPSYIHGTIGVHAGDDVGIFATGPQSHLFTGVMQQSTIPHLMAYASCIGNGPTLCDNED", "length": 543 }, "evidence": [ { "id": "RGD:2099", "url": "https://alliancegenome.org/gene/RGD:2099#orthology", "database": "AGR" }, { "id": "MGI:1924018", "url": "https://alliancegenome.org/gene/MGI:1924018#orthology", "database": "AGR" }, { "id": "MGI:87984", "url": "https://alliancegenome.org/gene/MGI:87984#orthology", "database": "AGR" }, { "id": "MGI:108009", "url": "https://alliancegenome.org/gene/MGI:108009#orthology", "database": "AGR" }, { "id": "MGI:87983", "url": "https://alliancegenome.org/gene/MGI:87983#orthology", "database": "AGR" }, { "id": "HGNC:438", "url": "https://alliancegenome.org/gene/HGNC:438#orthology", "database": "AGR" }, { "id": "HGNC:441", "url": "https://alliancegenome.org/gene/HGNC:441#orthology", "database": "AGR" }, { "id": "HGNC:437", "url": "https://alliancegenome.org/gene/HGNC:437#orthology", "database": "AGR" }, { "id": "RGD:2325055", "url": "https://alliancegenome.org/gene/RGD:2325055#orthology", "database": "AGR" }, { "id": "RGD:621650", "url": "https://alliancegenome.org/gene/RGD:621650#orthology", "database": "AGR" }, { "id": "RGD:2100", "url": "https://alliancegenome.org/gene/RGD:2100#orthology", "database": "AGR" }, { "id": "SGD:S000002889", "url": "https://alliancegenome.org/gene/SGD:S000002889#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "alkaline phosphatase activity", "id": "GO:0004035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004035", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM8", "url": "https://www.uniprot.org/uniprotkb/Q9VRM8" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM8", "url": "https://www.uniprot.org/uniprotkb/Q9VRM8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM8", "url": "https://www.uniprot.org/uniprotkb/Q9VRM8" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM8", "url": "https://www.uniprot.org/uniprotkb/Q9VRM8" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "Q9VRM8", "url": "https://www.uniprot.org/uniprotkb/Q9VRM8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 160, "end_pos": 162, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-DME-8847875", "name": "ARF1:GTP binds Golgin TRIP11", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VDG4-1", "Q9VIW9-1", "Q9VXS8-1", "Q9W275-1", "P61209-1", "M9PD70-1", "Q9W274-1", "Q24238-1", "Q9VH28-1", "Q9VHD0-1", "Q9VRM9-1", "Q9VRM8-1", "Q9W273-1" ], "evidence": [ { "id": "R-DME-8847875", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8847875" } ] }, { "id": "R-DME-8878787", "name": "ALPI dimer hydrolyses phosphate monoesters", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [ "R-ALL-8878780" ], "output_participant_list": [ "R-ALL-8878776" ], "enzyme_list": [ "Q9VDG4-1", "Q9VIW9-1", "Q9VXS8-1", "Q9W275-1", "M9PD70-1", "Q9W274-1", "Q24238-1", "Q9VH28-1", "Q9VHD0-1", "Q9VRM9-1", "Q9VRM8-1", "Q9W273-1" ], "evidence": [ { "id": "R-DME-8878787", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8878787" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-8878776", "participant_name": "Alcohol [extracellular region]", "crossref": [ { "id": "C00069", "database": "COMPOUND", "url": "" }, { "id": "30879", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-8878780", "participant_name": "phosphate monoester [extracellular region]", "crossref": [ { "id": "7794", "database": "ChEBI", "url": "" }, { "id": "Orthophosphoric-Monoesters", "database": "AraCyc", "url": "" }, { "id": "C01153", "database": "KEGG Gene", "url": "" }, { "id": "C01153", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "M9PD70", "gene_name": "Alp1", "activity": [ { "ec_number": "3.1.3.1", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "M9PD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9PD70" } ] }, { "ec_number": "3.1.3.1", "activity": "", "evidence": [ { "id": "M9PD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9PD70" } ] } ] }, { "uniprot_ac": "P61209", "gene_name": "Arf1", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "P61209", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P61209" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "P61209", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P61209" } ] } ] }, { "uniprot_ac": "Q24238", "gene_name": "Alp4", "activity": [ { "ec_number": "3.1.3.1", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "Q24238", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q24238" } ] }, { "ec_number": "3.1.3.1", "activity": "", "evidence": [ { "id": "Q24238", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q24238" } ] } ] }, { "uniprot_ac": "Q9VDG4", "gene_name": "Alp5", "activity": [ { "ec_number": "3.1.3.1", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "Q9VDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VDG4" } ] }, { "ec_number": "3.1.3.1", "activity": "", "evidence": [ { "id": "Q9VDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VDG4" } ] } ] }, { "uniprot_ac": "Q9VH28", "gene_name": "Alp13", "activity": [ { "ec_number": "3.1.3.1", "activity": "a phosphate monoester + H2O = an alcohol 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"ec_number": "3.1.3.1", "activity": "", "evidence": [ { "id": "Q9VIW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VIW9" } ] } ] }, { "uniprot_ac": "Q9VRM8", "gene_name": "Alp10", "activity": [ { "ec_number": "3.1.3.1", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "Q9VRM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VRM8" } ] }, { "ec_number": "3.1.3.1", "activity": "", "evidence": [ { "id": "Q9VRM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VRM8" } ] } ] }, { "uniprot_ac": "Q9VRM9", "gene_name": "Alp9", "activity": [ { "ec_number": "3.1.3.1", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "Q9VRM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VRM9" } ] }, { "ec_number": "3.1.3.1", "activity": "", "evidence": [ { "id": "Q9VRM9", "database": "UniProtKB", "url": 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"categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-9013422", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9013422", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-9013424", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9013424", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_523938", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523938", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VRP3", "url": "https://www.uniprot.org/uniprotkb/Q9VRP3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VRP3-1", "url": "https://www.uniprot.org/uniprotkb/Q9VRP3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVRVINDESHFQAELAQAGIQLVVVDFTASWCGPCKRIAPIFETFPTKYPKAIFLKVDVDKCQDTAAGQGVSAMPTFIFYRNRTKIDRVQGADVNGLEAKIQEHIGTSGGEEGGEDYGQGLMELNTFISKQECECLNEADDHNLKHALASAGGYLQSDCDEQLILSITFNQAVKIHSLKFKAPSHLGPKDVKLFINQPRTIDFDMAESMNSVQDLSLAQKELESGVPVNLRYVKFQNVQNIQIFVKNNQSGGDVTQIDYIGFIGSPIMTTKMNDFKRVAGKKGESH", "length": 287, "header": "tr|Q9VRP3-1|Q9VRP3_DROME Isoform 1 of Thioredoxin-like OS=Drosophila melanogaster OX=7227 GN=Txl PE=1 SV=1 CANONICAL=Q9VRP3-1" }, "isoforms": [ { "isoform_ac": "Q9VRP3-1", "url": "https://www.uniprot.org/uniprotkb/Q9VRP3/entry#Q9VRP3-1", "sequence": { "sequence": "MSVRVINDESHFQAELAQAGIQLVVVDFTASWCGPCKRIAPIFETFPTKYPKAIFLKVDVDKCQDTAAGQGVSAMPTFIFYRNRTKIDRVQGADVNGLEAKIQEHIGTSGGEEGGEDYGQGLMELNTFISKQECECLNEADDHNLKHALASAGGYLQSDCDEQLILSITFNQAVKIHSLKFKAPSHLGPKDVKLFINQPRTIDFDMAESMNSVQDLSLAQKELESGVPVNLRYVKFQNVQNIQIFVKNNQSGGDVTQIDYIGFIGSPIMTTKMNDFKRVAGKKGESH", "length": 287, "header": "tr|Q9VRP3-1|Q9VRP3_DROME Isoform 1 of Thioredoxin-like OS=Drosophila melanogaster OX=7227 GN=Txl PE=1 SV=1 CANONICAL=Q9VRP3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VRP3", "url": "https://www.uniprot.org/uniprotkb/Q9VRP3" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VRP3", "url": "https://www.uniprot.org/uniprotkb/Q9VRP3" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VRP3", "url": "https://www.uniprot.org/uniprotkb/Q9VRP3" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VRP3", "url": "https://www.uniprot.org/uniprotkb/Q9VRP3" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VRP3", "url": "https://www.uniprot.org/uniprotkb/Q9VRP3" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VRP3", "url": "https://www.uniprot.org/uniprotkb/Q9VRP3" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VRP3", "url": "https://www.uniprot.org/uniprotkb/Q9VRP3" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VRP3", "url": "https://www.uniprot.org/uniprotkb/Q9VRP3" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VRP3", "url": "https://www.uniprot.org/uniprotkb/Q9VRP3" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"https://www.ncbi.nlm.nih.gov/gene/38656", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VRQ2", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VRQ2*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR003511", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003511", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036570", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036570", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045091", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045091", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG17498", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG17498", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WQFDVEI", "url": "https://omabrowser.org/oma/group/WQFDVEI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VRQ2", "url": "https://www.orthodb.org/?gene=Q9VRQ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11842", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11842", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11842:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11842:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02301", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02301", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-141405", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-141405", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-141430", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-141430", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-174184", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-174184", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-176409", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-176409", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-179409", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-179409", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_647991", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647991", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VRQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VRQ2-1", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTAQATKNCITLKGSAQIIVEYLKYGINSILFQRGIYPAEDFNNTQQYGLTILMSKDPKIKTFLQNVLSQTEEWLSKNMINKISMVITNAHTKEVLECWDFNMQAELGDGDISDPTKATTTKELSRIQNEIRDVMRQISATVSYLPLLDCICTFDIMIHTLQNTELPAKWDETGAIVIQNPQAVQLRSFSTGLHKVDTVVNYKMST", "length": 207, "header": "tr|Q9VRQ2-1|Q9VRQ2_DROME Isoform 1 of Mitotic spindle assembly checkpoint protein MAD2A OS=Drosophila melanogaster OX=7227 GN=mad2 PE=1 SV=1 CANONICAL=Q9VRQ2-1" }, "isoforms": [ { "isoform_ac": "Q9VRQ2-1", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ2/entry#Q9VRQ2-1", "sequence": { "sequence": "MSTAQATKNCITLKGSAQIIVEYLKYGINSILFQRGIYPAEDFNNTQQYGLTILMSKDPKIKTFLQNVLSQTEEWLSKNMINKISMVITNAHTKEVLECWDFNMQAELGDGDISDPTKATTTKELSRIQNEIRDVMRQISATVSYLPLLDCICTFDIMIHTLQNTELPAKWDETGAIVIQNPQAVQLRSFSTGLHKVDTVVNYKMST", "length": 207, "header": "tr|Q9VRQ2-1|Q9VRQ2_DROME Isoform 1 of Mitotic spindle assembly checkpoint protein MAD2A OS=Drosophila melanogaster OX=7227 GN=mad2 PE=1 SV=1 CANONICAL=Q9VRQ2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VRQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ2" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VRQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ2" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VRQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ2" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VRQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ2" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VRQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ2" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VRQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ2" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VRQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ2" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VRQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ2" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VRQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ2" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VRQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ2" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VRQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ2" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG17498", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG17498", "resource": "KEGG Pathway" }, { "id": "R-DME-141405", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-141405", "resource": "Reactome", "description": "Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components" }, { "id": "R-DME-141430", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-141430", "resource": "Reactome", "description": "Inactivation of APC/C via direct inhibition of the APC/C complex" }, { "id": "R-DME-174184", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-174184", "resource": "Reactome", "description": "Cdc20:Phospho-APC/C mediated degradation of Cyclin A" }, { "id": "R-DME-176409", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-176409", "resource": "Reactome", "description": "APC/C:Cdc20 mediated degradation of 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}, { "id": "MGI:1860374", "url": "https://alliancegenome.org/gene/MGI:1860374#orthology", "database": "AGR" }, { "id": "HGNC:6763", "url": "https://alliancegenome.org/gene/HGNC:6763#orthology", "database": "AGR" }, { "id": "FB:FBgn0035640", "url": "https://alliancegenome.org/gene/FB:FBgn0035640#orthology", "database": "AGR" }, { "id": "SGD:S000003567", "url": "https://alliancegenome.org/gene/SGD:S000003567#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q556Y9-1", "protein_name": "Mitotic spindle assembly checkpoint protein MAD2A", "gene_name": "mad2l1-1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MQAAVASKTNISLKGSTEIVTEFFSYSINTILFQRGLYPPESFTRVAKYGLPILVTNDQSLKDYLDNVLKQLSEWLLSGDVQKLVLVITDIVTKEVLERWVFDVTTDIPKEGEAPRQKPEKEIMNEIQAIIRQITASVTFLPLLPNACTFDLLVYTSKDLAVPQKWEESDPKFITNSQQVKLRSFTTTIHKVESMVAYKISND", "length": 203 }, "evidence": [ { "id": "Q9VRQ2", "url": "https://omabrowser.org/oma/group/Q9VRQ2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9LU93-1", "protein_name": "Mitotic spindle checkpoint protein MAD2", "gene_name": "MAD2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASKTAAAKDIITLHGSAAIVSEFFCYAANSILYNRAVYPEESFVKVKKYGLPMLLIEDESVKSFMSNLTSQISEWLEAGKLQRVVLVIMSKATGEVLERWNFRIETDNEVVDKGVSREKSDKEIMREIQAIMRQVASSVTYLPCLDETCVFDVLAYTDTDVAVPFTWIESDPKLIANPQMVKLHGFDTKIHKVDTLVSYKNDEWDEEE", "length": 209 }, "evidence": [ { "id": "Q9VRQ2", "url": "https://omabrowser.org/oma/group/Q9VRQ2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9Z1B5-1", "protein_name": "Mitotic spindle assembly checkpoint protein MAD2A", "gene_name": "Mad2l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAQQLAREQGITLRGSAEIVAEFFSFGINSILYQRGIYPSETFTRVQKYGLTLLTTTDPELIKYLNNVVEQLKEWLYKCSVQKLVVVISNIESGEVLERWQFDIECDKTAKEEGVRREKSQKAIQDEIRSVIRQITATVTFLPLLEVSCSFDLLIYTDKDLVVPEKWEESGPQFITNCEEVRLRSFTTTIHKVNSMVAYKTPVND", "length": 205 }, "evidence": [ { "id": "RGD:1310889", "url": "https://alliancegenome.org/gene/RGD:1310889#orthology", "database": "AGR" }, { "id": "MGI:1860374", "url": "https://alliancegenome.org/gene/MGI:1860374#orthology", "database": "AGR" }, { "id": "HGNC:6763", "url": "https://alliancegenome.org/gene/HGNC:6763#orthology", "database": "AGR" }, { "id": "FB:FBgn0035640", "url": "https://alliancegenome.org/gene/FB:FBgn0035640#orthology", "database": "AGR" }, { "id": "SGD:S000003567", "url": "https://alliancegenome.org/gene/SGD:S000003567#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 11, "go_terms": [ { "name": "kinetochore microtubule", "id": "GO:0005828", "url": 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"id": "Q9VRQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VRQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ2" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "Q9VRQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ2" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "Q9VRQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ2" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "Q9VRQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ2" } ], "pmid": "" }, { "name": "spindle matrix", "id": "GO:1990047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990047", "evidence": [ { "database": "UniProtKB", "id": "Q9VRQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ2" } ], "pmid": "" }, { "name": "mitotic spindle assembly checkpoint MAD1-MAD2 complex", "id": "GO:1990728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990728", "evidence": [ { "database": "UniProtKB", "id": "Q9VRQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "male germ-line stem cell asymmetric division", "id": "GO:0048133", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048133", "evidence": [ { "database": "UniProtKB", "id": "Q9VRQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ2" } ], "pmid": "" }, { "name": "regulation of mitotic cell cycle", "id": "GO:0007346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007346", "evidence": [ { "database": "UniProtKB", "id": "Q9VRQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ2" } ], "pmid": "" }, { "name": "mitotic spindle assembly checkpoint signaling", "id": "GO:0007094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007094", "evidence": [ { "database": "UniProtKB", "id": "Q9VRQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ2" } ], "pmid": "" }, { "name": "regulation of mitotic cell cycle spindle assembly checkpoint", "id": "GO:0090266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090266", "evidence": [ { "database": "UniProtKB", "id": "Q9VRQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ2" } ], "pmid": "" }, { "name": "regulation of mitotic spindle assembly", "id": "GO:1901673", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901673", "evidence": [ { "database": "UniProtKB", "id": "Q9VRQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ2" } ], "pmid": "" }, { "name": "chromosome organization", "id": "GO:0051276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051276", "evidence": [ { "database": "UniProtKB", "id": "Q9VRQ2", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 44, "end_pos": 46, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VRQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ2" }, { "id": "PS50815", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50815" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HORMA", "eco_id": "ECO_0000259", "start_pos": 14, "end_pos": 201, "start_aa": "Lys", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA 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"https://www.ncbi.nlm.nih.gov/protein/NP_647992" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VRQ4", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG5568", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ4", "locus": { "chromosome": "3L", "start_pos": 5873518, "end_pos": 5871501, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0035641", "url": "https://www.ensemblgenomes.org/id/FBgn0035641" } ] } } ], "crossref": [ { "id": "FB:FBgn0035641", "url": "https://alliancegenome.org/gene/FB:FBgn0035641", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0035641", "url": "https://bgee.org/?page=gene&gene_id=FBgn0035641", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05911", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05911", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0035641", "url": "https://flybase.org/reports/FBgn0035641", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "38658", "url": "https://www.ncbi.nlm.nih.gov/gene/38658", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VRQ4", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VRQ4*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR000873", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000873", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042099", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042099", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045851", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045851", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG5568", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG5568", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MVPAQWQ", "url": "https://omabrowser.org/oma/group/MVPAQWQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VRQ4", "url": "https://www.orthodb.org/?gene=Q9VRQ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24096", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24096", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24096:SF353", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24096:SF353", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00501", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00501", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13193", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13193", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_647992", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647992", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VRQ4", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VRQ4-1", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGELQAGKSPFKTRNTFDENLKIWSGGEKRSLFSPDLSIGEIIFQQMERNAMLTAQISVTENTELTWKDIQTNAMKVASYMRKLGLEQGDFVGVIGRLTTHLTALAYACFFNGTPYHALHTEYEQSAIERLFGITKPRLIFCDGDEFEKVQAATKGLQVQIVTMRNHPAGILRIQDILTTPVEMNFRPVRLKDGTDQLLAILSSSGTSGLPKAVTISNSHQIIGSFLPVDSSIIQYNPNTLDWASGITMTINAAVFSLTSIIEDCDFDPANLCGLIEKYRISMVFVSSSQLAMLSNCPEFYAADLSSVKYFFYGGSNCSLEVQNKIRSRLSNECVNFSYTLTELNSPGCLNFNFDEKPNSVGRPVRGIQIKIVNELGEAQGPNVVGEICFNNGQKWPGYYKNPEETKKMQDSENWFHTGDLGYMDEDGYLFIIDRLKDMLKYQTIMYYPSEIESVIAEMPNVVEACVFGIWDPVYGDKAAASVVKKQGTQLEAQDVVEYVRKRIPAKFKQLNGGALIVDHIIQSGNRKANRAATKAEFLRIMEKN", "length": 545, "header": "tr|Q9VRQ4-1|Q9VRQ4_DROME Isoform 1 of Long-chain-fatty-acid--CoA ligase OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG5568 PE=3 SV=3 CANONICAL=Q9VRQ4-1" }, "isoforms": [ { "isoform_ac": "Q9VRQ4-1", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ4/entry#Q9VRQ4-1", "sequence": { "sequence": "MGELQAGKSPFKTRNTFDENLKIWSGGEKRSLFSPDLSIGEIIFQQMERNAMLTAQISVTENTELTWKDIQTNAMKVASYMRKLGLEQGDFVGVIGRLTTHLTALAYACFFNGTPYHALHTEYEQSAIERLFGITKPRLIFCDGDEFEKVQAATKGLQVQIVTMRNHPAGILRIQDILTTPVEMNFRPVRLKDGTDQLLAILSSSGTSGLPKAVTISNSHQIIGSFLPVDSSIIQYNPNTLDWASGITMTINAAVFSLTSIIEDCDFDPANLCGLIEKYRISMVFVSSSQLAMLSNCPEFYAADLSSVKYFFYGGSNCSLEVQNKIRSRLSNECVNFSYTLTELNSPGCLNFNFDEKPNSVGRPVRGIQIKIVNELGEAQGPNVVGEICFNNGQKWPGYYKNPEETKKMQDSENWFHTGDLGYMDEDGYLFIIDRLKDMLKYQTIMYYPSEIESVIAEMPNVVEACVFGIWDPVYGDKAAASVVKKQGTQLEAQDVVEYVRKRIPAKFKQLNGGALIVDHIIQSGNRKANRAATKAEFLRIMEKN", "length": 545, "header": "tr|Q9VRQ4-1|Q9VRQ4_DROME Isoform 1 of Long-chain-fatty-acid--CoA ligase OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG5568 PE=3 SV=3 CANONICAL=Q9VRQ4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VRQ4", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ4" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VRQ4", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ4" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VRQ4", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ4" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VRQ4", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ4" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VRQ4", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ4" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VRQ4", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ4" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VRQ4", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ4" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VRQ4", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ4" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VRQ4", "url": "https://www.uniprot.org/uniprotkb/Q9VRQ4" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, 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"2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VRS9", "url": "https://www.uniprot.org/uniprotkb/Q9VRS9" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VRS9", "url": 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Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VRS9", "url": "https://www.uniprot.org/uniprotkb/Q9VRS9" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VRS9", "url": "https://www.uniprot.org/uniprotkb/Q9VRS9" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VRS9", "url": "https://www.uniprot.org/uniprotkb/Q9VRS9" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VRS9", "url": "https://www.uniprot.org/uniprotkb/Q9VRS9" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VRU8", "url": "https://www.uniprot.org/uniprotkb/Q9VRU8" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VRU8", "url": "https://www.uniprot.org/uniprotkb/Q9VRU8" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VRU8", "url": "https://www.uniprot.org/uniprotkb/Q9VRU8" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VRU8", "url": "https://www.uniprot.org/uniprotkb/Q9VRU8" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VRU8", "url": "https://www.uniprot.org/uniprotkb/Q9VRU8" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VRV0/entry#names_and_taxonomy" } ] }, { "name": "Prdm13-PA", "type": "synonym", "evidence": [ { "id": "NP_648032", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648032" } ] } ], "function": [], "disease": [ { "disease_id": "DOID:0060264", "recommended_name": { "id": "DOID:0060264", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0060264", "name": "pontocerebellar hypoplasia", "description": "A neurodegenerative disease that is characterized by underdevelopment of the pons and cerebellum." }, "synonyms": [ { "id": "DOID:0060264", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0060264", "name": "PCH", "description": "" }, { "id": "MONDO:0011866", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011866", "name": "pontocerebellar hypoplasia type 1A", "description": "Any non-syndromic pontocerebellar hypoplasia 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"DOID:0112328", "DOID:0112322" ], "evidence": [ { "id": "0060264", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060264" } ] }, { "disease_id": "DOID:0070439", "recommended_name": { "id": "DOID:0070439", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070439", "name": "North Carolina macular dystrophy", "description": "A retinal macular dystrophy characterized by limited drusen, larger confluent drusen, or severe colobomatous-like chorioretinal atrophy in the central macular region present at birth that are nonprogressive that has_material_basis_in heterozygous mutation in a DNase I hypersensitivity site on chromosome 6q16 upstream of the PRDM13 gene." }, "synonyms": [ { "id": "DOID:0070439", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070439", "name": "MCDR1", "description": "" }, { "id": "DOID:0070439", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070439", "name": "NCMD", "description": "" }, { "id": "DOID:0070439", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070439", "name": "central areolar pigment epithelial dystrophy", "description": "" }, { "id": "DOID:0070439", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070439", "name": "central retinal pigment epithelial dystrophy", "description": "" }, { "id": "DOID:0070439", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070439", "name": "progressive foveal dystrophy", "description": "" }, { "id": "DOID:0070439", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070439", "name": "retinal macular dystrophy 1", "description": "" }, { "id": "MONDO:0007630", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007630", "name": "North Carolina macular dystrophy", "description": "North Carolina macular dystrophy (NCMD) is a non-progressive 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PR/SET domain 13 OS=Drosophila melanogaster OX=7227 GN=Prdm13 PE=4 SV=1 CANONICAL=Q9VRV0-1" }, "isoforms": [ { "isoform_ac": "Q9VRV0-1", "url": "https://www.uniprot.org/uniprotkb/Q9VRV0/entry#Q9VRV0-1", "sequence": { "sequence": "MHTTAQLDSLEQKRSASLIFRIEQLLPSTSITPTSMTTSSTETTLTATTSTASPAKRMRMSNPRPGVYASQYTPKDTCSMAIPTSALLGSTVMPTDGSRSHCQLSNGELIVSGSLLRQIKLSEDVYSFNAIFELHGGQVRVRLVRDVAREDEIVAWFGEELVLLMGIPFLTPLNIQGNSRYMCHLCHLTFETPHPLKIHLALGCGRSAMDILWMRLHYALKAAARSHTETQHSPIPATSSTSSASPTHSPPPQMPPRFSAFRPIAALTQSLPMVPVTTAATPLSYLPSMSMATAPLSTNPMNAAAQIEAIVSNMGASKQGHLCIYCGKVYSRKYGLKIHIRTHTGFKPLKCKFCLRPFGDPSNLNKHVRLHLQTHPSSSAGVADGGASGADMDGDVDIEGETDADYQCHVCHKSFPRRRDLQRHMETRHGGHHSHSHSESRSSSTSTSSTTTMTATVTTSTSKSS", "length": 465, "header": "tr|Q9VRV0-1|Q9VRV0_DROME Isoform 1 of PR/SET domain 13 OS=Drosophila melanogaster OX=7227 GN=Prdm13 PE=4 SV=1 CANONICAL=Q9VRV0-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 95, "start_aa": "Thr", "end_pos": 95, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr95", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VRV0", "url": "https://www.uniprot.org/uniprotkb/Q9VRV0" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VRV0", "url": "https://www.uniprot.org/uniprotkb/Q9VRV0" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VRV0", "url": "https://www.uniprot.org/uniprotkb/Q9VRV0" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VRV0", "url": "https://www.uniprot.org/uniprotkb/Q9VRV0" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VRV0", "url": "https://www.uniprot.org/uniprotkb/Q9VRV0" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VRV0", "url": "https://www.uniprot.org/uniprotkb/Q9VRV0" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VRV0", "url": "https://www.uniprot.org/uniprotkb/Q9VRV0" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VRV0", "url": "https://www.uniprot.org/uniprotkb/Q9VRV0" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VRV0", "url": "https://www.uniprot.org/uniprotkb/Q9VRV0" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VRV0", "url": "https://www.uniprot.org/uniprotkb/Q9VRV0" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VRV0", "url": "https://www.uniprot.org/uniprotkb/Q9VRV0" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], 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], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VRV0", "url": "https://www.uniprot.org/uniprotkb/Q9VRV0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VRV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VRV0" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 321, "end_pos": 348, "start_aa": "His", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], 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"https://www.uniprot.org/uniprotkb/Q9VRV4" } ] }, { "name": "Dmel_CG10270", "type": "synonym", "evidence": [ { "id": "Q9VRV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VRV4" } ] }, { "name": "d19b", "type": "synonym", "evidence": [ { "id": "NP_477297", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_477297" }, { "id": "Q9VRV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VRV4" } ] } ], "protein_names": [ { "name": "CG10270-PA", "type": "synonym", "evidence": [ { "id": "NP_477297", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_477297" } ] }, { "name": "D19B-PA", "type": "synonym", "evidence": [ { "id": "NP_477297", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_477297" } ] }, { "name": "D19B", "type": "synonym", "evidence": [ { "id": "NP_477297", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_477297" }, { "id": "Q9VRV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VRV4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VRV4", "url": "https://www.uniprot.org/uniprotkb/Q9VRV4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "D19B", "url": "https://www.uniprot.org/uniprotkb/Q9VRV4", "locus": { "chromosome": "3L", "start_pos": 6182176, "end_pos": 6184920, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0022699", "url": "https://www.ensemblgenomes.org/id/FBgn0022699" } ] } } ], "crossref": [ { "id": "FB:FBgn0022699", "url": "https://alliancegenome.org/gene/FB:FBgn0022699", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0022699", "url": "https://bgee.org/?page=gene&gene_id=FBgn0022699", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0022699", "url": "https://flybase.org/reports/FBgn0022699", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "38717", "url": "https://www.ncbi.nlm.nih.gov/gene/38717", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VRV4", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VRV4*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR012934", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012934", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG10270", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG10270", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SEMHPCT", "url": "https://omabrowser.org/oma/group/SEMHPCT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VRV4", "url": "https://www.orthodb.org/?gene=Q9VRV4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24393", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24393", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24393:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24393:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07776", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07776", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13912", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13912", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_477297", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_477297", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VRV4", "url": "https://www.uniprot.org/uniprotkb/Q9VRV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VRV4-1", "url": "https://www.uniprot.org/uniprotkb/Q9VRV4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNEESQYSIHTVCRTCLSTVDDSAAYDLFRVPGLAKKLCVCTSLSVEQADGFPKNLCNVCFSKLNDLHDFQKQCVDSVQKFQDLVASNAFACQTNFDVLDTSAAVADLPGEEEDNVHFDPLLNSKIEIIENEEDVFKMLESVEKEVEEVEMEMEQPFGRVSQDDSFESGNDNDLDADFQISSDDDIPLAQRSRRGATRGSKAKGKPKSAAKRQEEESEESEETSSSDDSDGNPKDKPKRKRIPATERDRHRLIDCHICHQKFKKAIRYEEHMKHHNDLLPFQCTVESCRKGFTTANGLRVHVEHAHTETSAMHPCTYEGCNKSFARPVLLSFHMKRVHKVDTPQRDFPCTECEKVFRCPTALKKHMYKHTGEELPFACEICGKRFPINSVLRDHLLRHAGIKNHVCPYCGVGKTTRQEWNKHILTHTKEKKYECRQCDHASHNKQALANHVKVVHEKRKDFACQYCGKTFGKSHACKIHERSHTGEKCCECKICGKVFLFEKGLTKHLKTHEKRDLPKTQGTNALMGDGASGSSTIAKPSPHLRGRVERVDIAQLAGTVANPIPSVNLPSWSPQVNFTKKEGQHICPDCGKGFNHVSNMKLHYKVVHQKVKDFCCRFCPKRFAKKQYLRHHEYIHTGEKPYECKVCGKHFRQEQVLKTHMKVHDKPPRPPGKPKEPAGPKAESSTAVKRQQPKNFEQYQDPAAERAAATAELLAYQIEENEAKRKAEAELRKIQEAAFEQLNKLQKQSNTYDGFYAQKAEAEGTSVDALKLDHV", "length": 774, "header": "tr|Q9VRV4-1|Q9VRV4_DROME Isoform 1 of D19B OS=Drosophila melanogaster OX=7227 GN=D19B PE=3 SV=1 CANONICAL=Q9VRV4-1" }, "isoforms": [ { "isoform_ac": "Q9VRV4-1", "url": "https://www.uniprot.org/uniprotkb/Q9VRV4/entry#Q9VRV4-1", "sequence": { "sequence": "MNEESQYSIHTVCRTCLSTVDDSAAYDLFRVPGLAKKLCVCTSLSVEQADGFPKNLCNVCFSKLNDLHDFQKQCVDSVQKFQDLVASNAFACQTNFDVLDTSAAVADLPGEEEDNVHFDPLLNSKIEIIENEEDVFKMLESVEKEVEEVEMEMEQPFGRVSQDDSFESGNDNDLDADFQISSDDDIPLAQRSRRGATRGSKAKGKPKSAAKRQEEESEESEETSSSDDSDGNPKDKPKRKRIPATERDRHRLIDCHICHQKFKKAIRYEEHMKHHNDLLPFQCTVESCRKGFTTANGLRVHVEHAHTETSAMHPCTYEGCNKSFARPVLLSFHMKRVHKVDTPQRDFPCTECEKVFRCPTALKKHMYKHTGEELPFACEICGKRFPINSVLRDHLLRHAGIKNHVCPYCGVGKTTRQEWNKHILTHTKEKKYECRQCDHASHNKQALANHVKVVHEKRKDFACQYCGKTFGKSHACKIHERSHTGEKCCECKICGKVFLFEKGLTKHLKTHEKRDLPKTQGTNALMGDGASGSSTIAKPSPHLRGRVERVDIAQLAGTVANPIPSVNLPSWSPQVNFTKKEGQHICPDCGKGFNHVSNMKLHYKVVHQKVKDFCCRFCPKRFAKKQYLRHHEYIHTGEKPYECKVCGKHFRQEQVLKTHMKVHDKPPRPPGKPKEPAGPKAESSTAVKRQQPKNFEQYQDPAAERAAATAELLAYQIEENEAKRKAEAELRKIQEAAFEQLNKLQKQSNTYDGFYAQKAEAEGTSVDALKLDHV", "length": 774, "header": "tr|Q9VRV4-1|Q9VRV4_DROME Isoform 1 of D19B OS=Drosophila melanogaster OX=7227 GN=D19B PE=3 SV=1 CANONICAL=Q9VRV4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VRV4", "url": "https://www.uniprot.org/uniprotkb/Q9VRV4" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VRV4", "url": "https://www.uniprot.org/uniprotkb/Q9VRV4" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VRV4", "url": "https://www.uniprot.org/uniprotkb/Q9VRV4" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VRV4", "url": "https://www.uniprot.org/uniprotkb/Q9VRV4" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VRV4", "url": "https://www.uniprot.org/uniprotkb/Q9VRV4" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VRV4", "url": "https://www.uniprot.org/uniprotkb/Q9VRV4" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VRV4", "url": "https://www.uniprot.org/uniprotkb/Q9VRV4" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VRV4", "url": "https://www.uniprot.org/uniprotkb/Q9VRV4" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VRV4", "url": "https://www.uniprot.org/uniprotkb/Q9VRV4" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VRV4", "url": "https://www.uniprot.org/uniprotkb/Q9VRV4" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VRV4", "url": "https://www.uniprot.org/uniprotkb/Q9VRV4" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG10270", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG10270", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VRV4", "url": "https://www.uniprot.org/uniprotkb/Q9VRV4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q9VRV4", "url": "https://www.uniprot.org/uniprotkb/Q9VRV4" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "Q9VRV4", "url": "https://www.uniprot.org/uniprotkb/Q9VRV4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9VRV4", "url": "https://www.uniprot.org/uniprotkb/Q9VRV4" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q9VRV4", "url": "https://www.uniprot.org/uniprotkb/Q9VRV4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q9VRV4", "url": "https://www.uniprot.org/uniprotkb/Q9VRV4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 321, "end_pos": 323, "annotation": "n_glycosylation_sequon" }, { "start_pos": 576, "end_pos": 578, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VRV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VRV4" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 253, "end_pos": 280, "start_aa": "Ile", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q9VRV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VRV4" }, { "id": "PS51915", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51915" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ZAD", 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Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VRW1", "url": "https://www.uniprot.org/uniprotkb/Q9VRW1" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VRW1", "url": "https://www.uniprot.org/uniprotkb/Q9VRW1" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VRW1", "url": "https://www.uniprot.org/uniprotkb/Q9VRW1" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VRW1", "url": "https://www.uniprot.org/uniprotkb/Q9VRW1" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VS10-1", "uniprot_ac": "Q9VS10", "uniprot_id": "Q9VS10_DROME", "mass": { "chemical_mass": 48095.0, "monoisotopic_mass": 48095.0 }, "refseq": { "ac": "NP_001261494", "name": "uncharacterized protein, isoform B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261494" }, "gene_names": [ { "name": "Q9VS10", "type": "recommended", "evidence": [ { "id": "Q9VS10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VS10" } ] }, { "name": "CG8641", "type": "synonym", "evidence": [ { "id": "NP_001261494", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261494" }, { "id": "Q9VS10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VS10" } ] }, { "name": "Dmel\\CG8641", "type": "synonym", "evidence": [ { "id": "NP_001261494", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261494" }, { "id": "Q9VS10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VS10" } ] }, { "name": "Dmel_CG8641", "type": "synonym", "evidence": [ { "id": "Q9VS10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VS10" } ] }, { "name": "Q9VS10", "type": "synonym", "evidence": [ { "id": "NP_001261494", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261494" } ] } ], "protein_names": [ { "name": "GTP-binding protein Rhes", "type": "recommended", "evidence": [ { "id": "Q9VS10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VS10/entry#names_and_taxonomy" } ] }, { "name": "CG8641-PB", "type": "synonym", "evidence": [ { "id": "NP_001261494", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261494" } ] }, { "name": "uncharacterized protein, isoform B", "type": "synonym", "evidence": [ { "id": "NP_001261494", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261494" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VS10", "url": "https://www.uniprot.org/uniprotkb/Q9VS10" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Q9VS10", "url": "https://www.uniprot.org/uniprotkb/Q9VS10", "locus": { "chromosome": "3L", "start_pos": 7058930, "end_pos": 7077462, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0035733", "url": "https://www.ensemblgenomes.org/id/FBgn0035733" } ] } } ], "crossref": [ { "id": "FB:FBgn0035733", "url": "https://alliancegenome.org/gene/FB:FBgn0035733", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0035733", "url": "https://bgee.org/?page=gene&gene_id=FBgn0035733", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04143", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04143", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0035733", "url": "https://flybase.org/reports/FBgn0035733", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "38771", "url": "https://www.ncbi.nlm.nih.gov/gene/38771", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG8641", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG8641", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TPNQHRR", "url": "https://omabrowser.org/oma/group/TPNQHRR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VS10", "url": "https://www.orthodb.org/?gene=Q9VS10", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46149", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46149", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46149:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46149:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q9VS10", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q9VS10", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001261494", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261494", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VS10", "url": "https://www.uniprot.org/uniprotkb/Q9VS10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VS10-1", "url": "https://www.uniprot.org/uniprotkb/Q9VS10-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYRCKNWFCARSNNNNYVDVALSEAPPIHPSAATTTTPNSRNFSASNNNNVRSNSSKSNQQTAAHRGATTHPTQIPHTHHPSTTHSTDEASPPQAHVVTFLDESTAGGSNGAVTSSRLVTTAELHQAHMLEHHSNLDAIEQADDFIYGPGAGLSLCDDSLPSAKNCYRLVMLGSSRAGKSSIVARFLGNRFEEAYTPTIEEFHRKLYRIRNEVFQLDILDTSGYHPFPAMRRLSFLTGDLFILVFSMDSRESFEEVVRLRENILETKWAALNPGSGFKKKSLPKIPMILAGNKCDRDFKTVQVDEVMGYIAGQDNCCTFVECSARQNYRIDDLFHSLFTVSNLPLEMTPNHHRRLVSVFGAPSPLPPHGSAVGGTKKNALSIKRRFSDACGVVTPNARRPSIRTDLNLMRSKTMALNEGEGVRSPSRWNRCALM", "length": 434, "header": "tr|Q9VS10-1|Q9VS10_DROME Isoform 1 of GTP-binding protein Rhes OS=Drosophila melanogaster OX=7227 GN=Q9VS10 PE=3 SV=1 CANONICAL=Q9VS10-1" }, "isoforms": [ { "isoform_ac": "Q9VS10-1", "url": "https://www.uniprot.org/uniprotkb/Q9VS10/entry#Q9VS10-1", "sequence": { "sequence": "MYRCKNWFCARSNNNNYVDVALSEAPPIHPSAATTTTPNSRNFSASNNNNVRSNSSKSNQQTAAHRGATTHPTQIPHTHHPSTTHSTDEASPPQAHVVTFLDESTAGGSNGAVTSSRLVTTAELHQAHMLEHHSNLDAIEQADDFIYGPGAGLSLCDDSLPSAKNCYRLVMLGSSRAGKSSIVARFLGNRFEEAYTPTIEEFHRKLYRIRNEVFQLDILDTSGYHPFPAMRRLSFLTGDLFILVFSMDSRESFEEVVRLRENILETKWAALNPGSGFKKKSLPKIPMILAGNKCDRDFKTVQVDEVMGYIAGQDNCCTFVECSARQNYRIDDLFHSLFTVSNLPLEMTPNHHRRLVSVFGAPSPLPPHGSAVGGTKKNALSIKRRFSDACGVVTPNARRPSIRTDLNLMRSKTMALNEGEGVRSPSRWNRCALM", "length": 434, "header": "tr|Q9VS10-1|Q9VS10_DROME Isoform 1 of GTP-binding protein Rhes OS=Drosophila melanogaster OX=7227 GN=Q9VS10 PE=3 SV=1 CANONICAL=Q9VS10-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VS10", "url": "https://www.uniprot.org/uniprotkb/Q9VS10" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VS10", "url": "https://www.uniprot.org/uniprotkb/Q9VS10" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VS10", "url": "https://www.uniprot.org/uniprotkb/Q9VS10" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VS10", "url": "https://www.uniprot.org/uniprotkb/Q9VS10" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VS10", "url": "https://www.uniprot.org/uniprotkb/Q9VS10" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VS10", "url": "https://www.uniprot.org/uniprotkb/Q9VS10" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VS10", "url": "https://www.uniprot.org/uniprotkb/Q9VS10" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VS10", "url": "https://www.uniprot.org/uniprotkb/Q9VS10" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VS10", "url": "https://www.uniprot.org/uniprotkb/Q9VS10" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VS10", "url": "https://www.uniprot.org/uniprotkb/Q9VS10" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VS10", "url": "https://www.uniprot.org/uniprotkb/Q9VS10" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG8641", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG8641", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1N7P6-1", "protein_name": "3.6.5.2", "gene_name": "rasd2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MIPAGSMEVNATDKAFLSVDGTATLTSCSYHSATVDASLQCTHPESKARVVRSSSTGKRPSSSERKPRRSLDPLSQLHKTKHMRYEVKNDELVSVKPSHYRRVVVLGAPRVGKTALIRRFLGEEVFEEHYEPTSEDFHSKLYHIRGERYQLDILDASKERDFPAKRRLTILTGDIFLLVFSVTDRDSFTEVCSLREEIFTAKSKLTKSKENRQLPIIICANKADVDSPRAVQRSDVAQCLGEDSVLFEVSAKTCTNLEEMFETLAVLGGLPTETRPSLHRDISIHTYHALSSRKRNKRAVNEPCGAVHPLARRPSFSSDLRRVLGPSTPKKSTPIERCQIQ", "length": 341 }, "evidence": [ { "id": "HGNC:18229", "url": "https://alliancegenome.org/gene/HGNC:18229#orthology", "database": "AGR" }, { "id": "HGNC:15828", "url": "https://alliancegenome.org/gene/HGNC:15828#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": 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] }, { "id": "IPR014352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022408", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022408", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035984", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035984", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG8628", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG8628", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AKFEAWN", "url": "https://omabrowser.org/oma/group/AKFEAWN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VS22", "url": "https://www.orthodb.org/?gene=Q9VS22", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23310", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23310", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23310:SF137", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23310:SF137", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00887", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00887", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-77289", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-77289", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001163366", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001163366", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VS22", "url": "https://www.uniprot.org/uniprotkb/Q9VS22", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VS22-1", "url": "https://www.uniprot.org/uniprotkb/Q9VS22-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVSFEEATELANKFTKKPTDAEFLEFYGLFKQATVGDVNIEKPGALALKDKAKYEAWSSNKGLSKEAAKEAYVKVYEKYAPKYA", "length": 84, "header": "tr|Q9VS22-1|Q9VS22_DROME Isoform 1 of Acyl-CoA binding protein 3, isoform B OS=Drosophila melanogaster OX=7227 GN=Acbp3 PE=1 SV=2 CANONICAL=Q9VS22-1" }, "isoforms": [ { "isoform_ac": "Q9VS22-1", "url": "https://www.uniprot.org/uniprotkb/Q9VS22/entry#Q9VS22-1", "sequence": { "sequence": "MVSFEEATELANKFTKKPTDAEFLEFYGLFKQATVGDVNIEKPGALALKDKAKYEAWSSNKGLSKEAAKEAYVKVYEKYAPKYA", "length": 84, "header": "tr|Q9VS22-1|Q9VS22_DROME Isoform 1 of Acyl-CoA binding protein 3, isoform B OS=Drosophila melanogaster OX=7227 GN=Acbp3 PE=1 SV=2 CANONICAL=Q9VS22-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VS22", "url": "https://www.uniprot.org/uniprotkb/Q9VS22" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VS22", "url": "https://www.uniprot.org/uniprotkb/Q9VS22" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VS22", "url": "https://www.uniprot.org/uniprotkb/Q9VS22" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VS22", "url": "https://www.uniprot.org/uniprotkb/Q9VS22" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VS22", "url": "https://www.uniprot.org/uniprotkb/Q9VS22" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VS22", "url": "https://www.uniprot.org/uniprotkb/Q9VS22" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VS22", "url": "https://www.uniprot.org/uniprotkb/Q9VS22" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VS22", "url": "https://www.uniprot.org/uniprotkb/Q9VS22" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VS22", "url": "https://www.uniprot.org/uniprotkb/Q9VS22" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VS22", "url": "https://www.uniprot.org/uniprotkb/Q9VS22" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VS22", "url": "https://www.uniprot.org/uniprotkb/Q9VS22" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG8628", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG8628", "resource": "KEGG Pathway" }, { "id": "R-DME-77289", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-77289", "resource": "Reactome", "description": "Mitochondrial Fatty Acid Beta-Oxidation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5Y857-1", "protein_name": "Acyl-CoA-binding protein", "gene_name": "Dbi-ps3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQAEFDKAAEEVKCLKTQPMDEEMLFIYSHFKQATVGDINTDRPGLLDLKGKAKWDSWNKLKGTSKKNAMKTYVEKVCLLLKKKKRFIKLKLLIVFYLKPNC", "length": 103 }, "evidence": [ { "id": "HGNC:2690", "url": "https://alliancegenome.org/gene/HGNC:2690#orthology", "database": "AGR" }, { "id": "FB:FBgn0250836", "url": "https://alliancegenome.org/gene/FB:FBgn0250836#orthology", "database": "AGR" }, { "id": "RGD:1564239", "url": "https://alliancegenome.org/gene/RGD:1564239#orthology", "database": "AGR" }, { 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"evidence": [ { "id": "MGI:1925495", "url": "https://alliancegenome.org/gene/MGI:1925495#orthology", "database": "AGR" }, { "id": "HGNC:17715", "url": "https://alliancegenome.org/gene/HGNC:17715#orthology", "database": "AGR" }, { "id": "HGNC:2690", "url": "https://alliancegenome.org/gene/HGNC:2690#orthology", "database": "AGR" }, { "id": "FB:FBgn0250836", "url": "https://alliancegenome.org/gene/FB:FBgn0250836#orthology", "database": "AGR" }, { "id": "RGD:1564239", "url": "https://alliancegenome.org/gene/RGD:1564239#orthology", "database": "AGR" }, { "id": "RGD:68360", "url": "https://alliancegenome.org/gene/RGD:68360#orthology", "database": "AGR" }, { "id": "RGD:2490", "url": "https://alliancegenome.org/gene/RGD:2490#orthology", "database": "AGR" }, { "id": "SGD:S000003269", "url": "https://alliancegenome.org/gene/SGD:S000003269#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P42281-1", "protein_name": 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"Rattus norvegicus", "sequence": { "sequence": "MSQVEFEMACASLKQLKGPLSDQEKLLVYSFYKQATQGDCNIPVPPATDVKAKAKWEAWMVNKGMSKMDAMRIYIAKVEELKKNETC", "length": 87 }, "evidence": [ { "id": "FB:FBgn0250836", "url": "https://alliancegenome.org/gene/FB:FBgn0250836#orthology", "database": "AGR" }, { "id": "RGD:68360", "url": "https://alliancegenome.org/gene/RGD:68360#orthology", "database": "AGR" }, { "id": "SGD:S000003269", "url": "https://alliancegenome.org/gene/SGD:S000003269#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8N6N7-1", "protein_name": "Acyl-CoA-binding domain-containing protein 7", "gene_name": "ACBD7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALQADFDRAAEDVRKLKARPDDGELKELYGLYKQAIVGDINIACPGMLDLKGKAKWEAWNLKKGLSTEDATSAYISKAKELIEKYGI", "length": 88 }, "evidence": [ { "id": "MGI:1925495", "url": "https://alliancegenome.org/gene/MGI:1925495#orthology", "database": "AGR" }, { "id": "HGNC:17715", "url": 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}, { "id": "SGD:S000003269", "url": "https://alliancegenome.org/gene/SGD:S000003269#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VLS4-1", "protein_name": "Acyl-CoA binding protein 1, isoform B", "gene_name": "Acbp1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSELQEFNQAAEDVKNLNTTPGDNDLLELYSLYKQATVGDCNTDKPGFLDFKGKAKWEAWNNRKGMSNTDAQAAYITKVKALIAAVGLKS", "length": 90 }, "evidence": [ { "id": "MGI:1925495", "url": "https://alliancegenome.org/gene/MGI:1925495#orthology", "database": "AGR" }, { "id": "HGNC:17715", "url": "https://alliancegenome.org/gene/HGNC:17715#orthology", "database": "AGR" }, { "id": "HGNC:2690", "url": "https://alliancegenome.org/gene/HGNC:2690#orthology", "database": "AGR" }, { "id": "RGD:1564239", "url": "https://alliancegenome.org/gene/RGD:1564239#orthology", "database": "AGR" }, { "id": "RGD:68360", "url": "https://alliancegenome.org/gene/RGD:68360#orthology", 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"name": "Dmel\\CG14830", "type": "synonym", "evidence": [ { "id": "NP_001246653", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001246653" } ] }, { "name": "Dmel_CG14830", "type": "synonym", "evidence": [ { "id": "Q9VS39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VS39" } ] } ], "protein_names": [ { "name": "CG14830-PB", "type": "synonym", "evidence": [ { "id": "NP_001246653", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001246653" } ] }, { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "Q9VS39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VS39/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein, isoform B", "type": "synonym", "evidence": [ { "id": "NP_001246653", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001246653" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VS39", "url": "https://www.uniprot.org/uniprotkb/Q9VS39" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG14830", "url": "https://www.uniprot.org/uniprotkb/Q9VS39", "locus": { "chromosome": "3L", "start_pos": 7250718, "end_pos": 7263920, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0035755", "url": "https://www.ensemblgenomes.org/id/FBgn0035755" } ] } } ], "crossref": [ { "id": "FB:FBgn0035755", "url": "https://alliancegenome.org/gene/FB:FBgn0035755", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0035755", "url": "https://bgee.org/?page=gene&gene_id=FBgn0035755", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0035755", "url": "https://flybase.org/reports/FBgn0035755", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "38800", "url": "https://www.ncbi.nlm.nih.gov/gene/38800", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VS39", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VS39*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "dme:Dmel_CG14830", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG14830", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EPVYVWI", "url": "https://omabrowser.org/oma/group/EPVYVWI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VS39", "url": "https://www.orthodb.org/?gene=Q9VS39", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR41155", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR41155", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR41155:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR41155:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "NP_001246653", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001246653", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VS39", "url": "https://www.uniprot.org/uniprotkb/Q9VS39", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VS39-1", "url": "https://www.uniprot.org/uniprotkb/Q9VS39-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHERQVKKLKGSHYVATHGRLTPDPPYVHSNRGYSTDGDETHSHRAPSERTYSEYTLTHERISPQYNGSRKKRSSSSNGNHQHQHLQSSYSHSQMGLSSSPDNGGPRSLSGPPPTRQPPRAPSALSYDQAGDAGSDIYVTSAAYKAPSEISRYSQRPVSRGAPRSVYSVASTAKTGRSARSTTRRGAKVETMSAPNPFCPNVKGVCCLMLLLNLGLILVTLGFVIVVQFYEPLYVWILGIVFLVFGFLTLIGCMIYCVYVFRDAKTPSQVRNEDLYWTRHWQKNIGYTPQEINYKADKYDAYSDRYSVSKLSGKYSDRESQRY", "length": 323, "header": "tr|Q9VS39-1|Q9VS39_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG14830 PE=4 SV=1 CANONICAL=Q9VS39-1" }, "isoforms": [ { "isoform_ac": "Q9VS39-1", "url": "https://www.uniprot.org/uniprotkb/Q9VS39/entry#Q9VS39-1", "sequence": { "sequence": "MHERQVKKLKGSHYVATHGRLTPDPPYVHSNRGYSTDGDETHSHRAPSERTYSEYTLTHERISPQYNGSRKKRSSSSNGNHQHQHLQSSYSHSQMGLSSSPDNGGPRSLSGPPPTRQPPRAPSALSYDQAGDAGSDIYVTSAAYKAPSEISRYSQRPVSRGAPRSVYSVASTAKTGRSARSTTRRGAKVETMSAPNPFCPNVKGVCCLMLLLNLGLILVTLGFVIVVQFYEPLYVWILGIVFLVFGFLTLIGCMIYCVYVFRDAKTPSQVRNEDLYWTRHWQKNIGYTPQEINYKADKYDAYSDRYSVSKLSGKYSDRESQRY", "length": 323, "header": "tr|Q9VS39-1|Q9VS39_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG14830 PE=4 SV=1 CANONICAL=Q9VS39-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, 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Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VS39", "url": "https://www.uniprot.org/uniprotkb/Q9VS39" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VS39", "url": "https://www.uniprot.org/uniprotkb/Q9VS39" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VS39", "url": "https://www.uniprot.org/uniprotkb/Q9VS39" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VS39", "url": "https://www.uniprot.org/uniprotkb/Q9VS39" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VS39", "url": "https://www.uniprot.org/uniprotkb/Q9VS39" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VS39", "url": "https://www.uniprot.org/uniprotkb/Q9VS39" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VS39", "url": "https://www.uniprot.org/uniprotkb/Q9VS39" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"name": "Behets disease", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "13241", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13241" } ] }, { "disease_id": "DOID:2228", "recommended_name": { "id": "DOID:2228", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2228", "name": "thrombocytosis", "description": "A blood platelet disease that is characterized by the presence of high platelet counts in the blood." }, "synonyms": [ { "id": "DOID:2228", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2228", "name": "Thrombocythaemia", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "2228", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2228" } ] }, { "disease_id": "DOID:4989", "recommended_name": { "id": "DOID:4989", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4989", "name": "pancreatitis", "description": "A pancreas disease that is characterized by inflammation of the pancreas." }, "synonyms": [ { "id": "MONDO:0008185", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008185", "name": "hereditary chronic pancreatitis", "description": "Hereditary chronic pancreatitis (HCP), a rare inherited form of pancreatitis is defined as recurrent acute pancreatitis and/or chronic pancreatitis in two first-degree relatives or 3 or more second-degree relatives in 2 or more generations, for which no predisposing factors are identified. HCP is characterized by irreversible damage to both exocrine and endocrine components of the pancreas." }, { "id": "MONDO:0008185", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008185", "name": "hereditary chronic pancreatitis", "description": "" }, { "id": "MONDO:0008185", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008185", "name": "hereditary pancreatitis", "description": "" }, { "id": "MONDO:0008185", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008185", "name": "HPC", "description": "" }, { "id": "MONDO:0008185", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008185", "name": "Hp", "description": "" }, { "id": "MONDO:0008185", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008185", "name": "PCTT", "description": "" }, { "id": "MONDO:0008185", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008185", "name": "autosomal dominant hereditary pancreatitis", "description": "" }, { "id": "MONDO:0008185", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008185", "name": "familial pancreatitis", "description": "" }, { "id": "MONDO:0008185", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008185", "name": "pancreatitis, calcific, included", "description": "" }, { "id": "MONDO:0008185", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008185", "name": "pancreatitis, chronic pancreatitis, chronic, susceptibility to, included", "description": "" }, { "id": "MONDO:0008185", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008185", "name": "pancreatitis, chronic, protection against, included", "description": "" }, { "id": "MONDO:0008185", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008185", "name": "pancreatitis, hereditary", "description": "" }, { "id": "MIM:167800", "resource": "MIM", "url": "https://www.omim.org/entry/167800", "name": "Pancreatitis, hereditary", "description": "Pancreatitis, hereditary" } ], "unlinked_id_list": [], "evidence": [ { "id": "4989", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4989" } ] }, { "disease_id": "DOID:784", "recommended_name": { "id": "DOID:784", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:784", "name": "chronic kidney disease", "description": "A kidney failure that is characterized by the gradual loss of kidney function, present for a minimum of 3 months. CKD is classified based on cause, glomerular filtration rate (GFR) category (G2-G5), and albuminuria category (A1-A3)." }, "synonyms": [ { "id": "DOID:784", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:784", "name": "CKD", "description": "" }, { "id": "DOID:784", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:784", "name": "CRF", "description": "" }, { "id": "DOID:784", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:784", "name": "chronic kidney failure", "description": "" }, { "id": "DOID:784", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:784", "name": "chronic renal disease", "description": "" }, { "id": "DOID:784", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:784", "name": "chronic renal failure syndrome", "description": "" }, { "id": "DOID:784", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:784", "name": "renal failure - chronic", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "784", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:784" } ] }, { "disease_id": "DOID:9351", "recommended_name": { "id": "DOID:9351", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9351", "name": "diabetes mellitus", "description": "A glucose metabolism disease that is characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both." }, "synonyms": [ { "id": "DOID:9351", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9351", "name": "diabetes", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "9351", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9351" } ] }, { "disease_id": "DOID:9352", "recommended_name": { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin." }, "synonyms": [ { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "NIDDM", "description": "" }, { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "non-insulin-dependent diabetes mellitus", "description": "" }, { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "type 2 diabetes", "description": "" }, { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "type II diabetes mellitus", "description": "" }, { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "insulin resistance", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type 2 diabetes mellitus", "description": "A type of diabetes mellitus that is characterized by insulin resistance or desensitization and increased blood glucose levels. This is a chronic disease that can develop gradually over the life of a patient and can be linked to both environmental factors and heredity." }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "NIDDM", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "T2D", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "T2DM", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "T2DM - type 2 diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "adult onset diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "adult-onset diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitis type 2", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitis type II", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent, association with", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent, late onset", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, type 2", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, type II", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes, type 2", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "insulin resistance, severe, digenic", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "non-insulin dependent diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "non-insulin dependent 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"https://monarchinitiative.org/disease/MONDO:0005148", "name": "type II diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type II diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent, 2", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "diabetes mellitus, noninsulin-dependent, 1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "diabetes mellitus, noninsulin-dependent 1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "diabetes mellitus, noninsulin-dependent, 1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "diabetes mellitus, noninsulin-dependent, type 1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "NIDDM1", "description": "" }, { "id": "MONDO:0011072", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011072", "name": "diabetes mellitus, noninsulin-dependent, 2", "description": "" }, { "id": "MONDO:0011072", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011072", "name": "NIDDM2", "description": "" }, { "id": "MONDO:0011072", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011072", "name": "diabetes mellitus, noninsulin-dependent, 2", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "diabetes mellitus, noninsulin-dependent, 3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "diabetes mellitus, noninsulin-dependent, 3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "diabetes mellitus, noninsulin-dependent, type 3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "type 2 diabetes mellitus 3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "NIDDM3", "description": "" }, { "id": "MONDO:0011955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011955", "name": "diabetes mellitus, noninsulin-dependent, 4", "description": "" }, { "id": "MONDO:0011955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011955", "name": "diabetes mellitus, noninsulin-dependent, 4", "description": "" }, { "id": "MONDO:0011955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011955", "name": "diabetes mellitus, noninsulin-dependent, type 4", "description": "" }, { "id": "MIM:125853", "resource": "MIM", "url": "https://www.omim.org/entry/125853", "name": "Type 2 diabetes mellitus", "description": "Type 2 diabetes mellitus" }, { "id": "MIM:601283", "resource": "MIM", "url": "https://www.omim.org/entry/601283", "name": "Type 2 diabetes mellitus 1", "description": "Type 2 diabetes mellitus 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ] }, { "disease_id": "DOID:9970", "recommended_name": { "id": "DOID:9970", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness." }, "synonyms": [ { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "inherited obesity", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "genetic obesity", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "genetic obesity (disease)", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": 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}, { "id": "38842", "url": "https://www.ncbi.nlm.nih.gov/gene/38842", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VS80", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VS80*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR000834", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000834", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG8539", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG8539", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "REWMTPM", "url": "https://omabrowser.org/oma/group/REWMTPM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VS80", "url": "https://www.orthodb.org/?gene=Q9VS80", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11705", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11705", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11705:SF140", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11705:SF140", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00246", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00246", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-2022377", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-2022377", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001261520", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261520", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VS80", "url": "https://www.uniprot.org/uniprotkb/Q9VS80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VS80-1", "url": "https://www.uniprot.org/uniprotkb/Q9VS80-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWKILCGIVVLVTIVVNQLSEAREVRRRRGLMLQLDNYLSYDGIMQYLDELALSHSNRVTLKDVARTYENRALKMAIITNGDGRPGKRVIFLDAALHSREWMTPAAALLTIHKLVVEFAENSDLLTDYDWHIMPLANPDGYEYSRNTERYWRNTRTPNGGNCFGTNLNRNFAVDWNVGFPELKDPCDENYAGSSPFSEVEARTVRDIMHGLVESKRAVMYLSLHTANRSVFYPWVYDTDPVSNQKEHDEIGRFVADRILQSTGTFIKTWQYAKYAGTFGGTSMDYALLAGFPLSFVFEMSGTGRDHVEYKFFPPARDIRHLAEESWTGIKAFAEKTIEKYPPSRVISYNPMVKLAENAATRNLGFNSMVATVCLFFTYLTNCNFF", "length": 385, "header": "tr|Q9VS80-1|Q9VS80_DROME Isoform 1 of Peptidase M14 domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG8539 PE=3 SV=1 CANONICAL=Q9VS80-1" }, "isoforms": [ { "isoform_ac": "Q9VS80-1", "url": "https://www.uniprot.org/uniprotkb/Q9VS80/entry#Q9VS80-1", "sequence": { "sequence": "MWKILCGIVVLVTIVVNQLSEAREVRRRRGLMLQLDNYLSYDGIMQYLDELALSHSNRVTLKDVARTYENRALKMAIITNGDGRPGKRVIFLDAALHSREWMTPAAALLTIHKLVVEFAENSDLLTDYDWHIMPLANPDGYEYSRNTERYWRNTRTPNGGNCFGTNLNRNFAVDWNVGFPELKDPCDENYAGSSPFSEVEARTVRDIMHGLVESKRAVMYLSLHTANRSVFYPWVYDTDPVSNQKEHDEIGRFVADRILQSTGTFIKTWQYAKYAGTFGGTSMDYALLAGFPLSFVFEMSGTGRDHVEYKFFPPARDIRHLAEESWTGIKAFAEKTIEKYPPSRVISYNPMVKLAENAATRNLGFNSMVATVCLFFTYLTNCNFF", "length": 385, "header": "tr|Q9VS80-1|Q9VS80_DROME Isoform 1 of Peptidase M14 domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG8539 PE=3 SV=1 CANONICAL=Q9VS80-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VS80", "url": "https://www.uniprot.org/uniprotkb/Q9VS80" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VS80", "url": "https://www.uniprot.org/uniprotkb/Q9VS80" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VS80", "url": "https://www.uniprot.org/uniprotkb/Q9VS80" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VS80", "url": "https://www.uniprot.org/uniprotkb/Q9VS80" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VS80", "url": "https://www.uniprot.org/uniprotkb/Q9VS80" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VS80", "url": "https://www.uniprot.org/uniprotkb/Q9VS80" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VS80", "url": "https://www.uniprot.org/uniprotkb/Q9VS80" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VS80", "url": "https://www.uniprot.org/uniprotkb/Q9VS80" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VS80", "url": "https://www.uniprot.org/uniprotkb/Q9VS80" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VS80", "url": "https://www.uniprot.org/uniprotkb/Q9VS80" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VS80", "url": "https://www.uniprot.org/uniprotkb/Q9VS80" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG8539", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG8539", "resource": "KEGG Pathway" }, { "id": "R-DME-2022377", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-2022377", "resource": "Reactome", "description": "Metabolism of Angiotensinogen to Angiotensins" } ], "orthologs": [ { "uniprot_canonical_ac": "B8JLQ9-1", "protein_name": "Carboxypeptidase O", "gene_name": "cpo", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMQASITSILVVLTLVAQDRLAGGLEHKSYDYTKYHTMDEISAWMNQMQRENPDVVSTMTYGQTYEKRNITLLKIGFSSTTPKKAIWMDCGIHAREWIAPAFCQHFVKEVLGSYKTDSRVNMLFKNLDFYITPVLNMDGYIYSWLNNSTRLWRKSRSPCHENSTCSGTDLNRNFYANWGMVGISRNCCSEVYNGATALSEPEAEAVTDFLGAHQNHLLCYLTIHSYGQLILVPYGHPNISAPNYDELMEVGLAAAKAIKAVHGKSYKVGSSPDVLYPNSGSSRDFARLIGIPYSFTFELRDEGQHGFILPEDQIQPTCQEAYEGAMSIINYVHDKNFKNTAITVTATLWTTLMALWISTSHVF", "length": 363 }, "evidence": [ { "id": "HGNC:21011", "url": "https://alliancegenome.org/gene/HGNC:21011#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070619-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070619-6#orthology", "database": "AGR" }, { "id": "FB:FBgn0035791", "url": "https://alliancegenome.org/gene/FB:FBgn0035791#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7F2H8-1", "protein_name": "Carboxypeptidase A6", "gene_name": "cpa6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MALRSTDVSSNVKSAVLLGCVLILCTAPNNVDSYLYNNRYVGDQVFRIIPSSKPEVQAVKQLFQNLTVDLWQPNSASLIRENSSIDVHVRRDKTHWLRNHLHQEHIYYEVLISNLQTEIEKQTGYRSSRKRRSELQYDYEVYHPLEEIQSWMFEMNRTHSHLVDLFSIGQSYEGRPLYVLQLGKRTRFFKKAVWIDCGVHAREWIGPAFCQWFVKEALNSYQHDSSMRRLMNQLNFYIMPVFNVDGYHYSWKMDRFWRKTRSKIPKYHCRGVDANRNWKVKWCDEGASLHPCDDTYCGPFPESEPEVKAVAKFLRKHKKRVKAYISMHAYAQMLLYPYSYKYATIPNFNCVESAAQNAVSALYSAYGVRYRYGPASSTLYVSSGSSMDWAYKNGIPYAFAFELRDTGYYGFLLPEALINPTCTETMRAVKTIASGLLRKCTK", "length": 442 }, "evidence": [ { "id": "MGI:3045348", "url": "https://alliancegenome.org/gene/MGI:3045348#orthology", "database": "AGR" }, { "id": "HGNC:17245", "url": "https://alliancegenome.org/gene/HGNC:17245#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7F897-1", "protein_name": "3.4.17.20", "gene_name": "cpb2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRALIQLAYFICFSIFLETCLCKVKHDQVLAITVSSQEHVEKVQNLTSHNETALWQPASPNYITTNSEVHLYIQSTSVQFVKEHLREHAITFRVLVENTAALVAMQIRNDTSDPRSGGVFYERYHSLEDIYYWINKTSREHSDMVKVILIGSSSEKRPLYVLKLSGKREEEVNRAMWMDCGIHAREWIAPAFCMWFVNYALAFYNQNTEITEMLNKMDIYILTVMNPDGYKYTWTTDRMWRKNRSENKDSYCAGVDLNRNFDANWCTKGASDDPCDPTYCGQFPESEPETQAVAKFLRSHKDTVKLYLSIHSYSQMLLFPYSCSYNEIPNHNELFELVKEASTKIRRYYRNNYKYGSGAKTIYLAPGGSDDWAYDLGIKYSFTFELQDRGQYGFLLPPSFIPQACNEALLAAKVIALHVINKTQ", "length": 424 }, "evidence": [ { "id": "MGI:1891837", "url": "https://alliancegenome.org/gene/MGI:1891837#orthology", "database": "AGR" }, { "id": "HGNC:2300", "url": "https://alliancegenome.org/gene/HGNC:2300#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1M4P0-1", "protein_name": "Carboxypeptidase A6", "gene_name": "Cpa6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKFLGKPRSLTAAFLPVCCLLLKILQPGHCHSYDNRYAGHKVIRLIPKSEEEALALKSVSHQLKVDLWQPSSISYVSEGTITDVRVTQNASRTLLAILQETNIQYKVLIEDLQKAVENENSVHTQRNRRSLSEYNYEVYHSLEDIQSWMHHLNQTQPGLVRVFPIGRSFEGRSLLIIQLGRKSQVYKRAVWIDCGIHAREWIGPAFCQWFVKEAILTYKTDPAMRKMLNHLYFYIMPVLNVDGYHFSWTHDRFWRKTRSRNSKFHCRGVDANRNWKVKWCDEGASADPCDDTYCGPFPESEPEVKAVANFLRKHRKRIRAYLSFHAYAQMLLYPYSYKHATIPNFSCVEFAAHKAVKALRSVHGIRYRHGPASQTLYVSSGNSMDWAYKNGIPYSFAFELRDTGYFGFLLPEMLIKPTCTETMLAVKNITMHLLKNCP", "length": 438 }, "evidence": [ { "id": "MGI:3045348", "url": "https://alliancegenome.org/gene/MGI:3045348#orthology", "database": "AGR" }, { "id": "HGNC:17245", "url": "https://alliancegenome.org/gene/HGNC:17245#orthology", "database": "AGR" }, { "id": "RGD:1311764", "url": "https://alliancegenome.org/gene/RGD:1311764#orthology", "database": "AGR" }, { "id": "FB:FBgn0035791", "url": "https://alliancegenome.org/gene/FB:FBgn0035791#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QJN9-1", "protein_name": "Carboxypeptidase B", "gene_name": "cpb1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKLFLLLGLVAVALCEPITFVGDKVLQLKPINDEHVTIIRELGEKIKLDFWKPRSADLVSIDMTVDIHVPAAQLAMVSTILQQSDMEVKVMIDNLQEAVKGQMDNRSPTKGHDYTKYNSWATINDWAISISSANPDLISRQSIGNTYEGRTMHLLKIGKNTGSNKPAVFMDCGFHAREWITHAFCQWFVNEAVSTYGSDPDMTNLLDRMDFFVLPVFNIDGYEYTWNRDRMWRKTRSKNSGSSCIGTDPNRNFNAGWCTVGASSNPCSDTYCGSSPESEIESKNLANFIRTNKSVIKAYLTVHSYSQLLLFPYSYKYDLAAHHSELMSVSQGAIAALRSLYGTKYTSGPGAATIYPAAGGSDDWAYDLGVKYSYTFELRDEGRYGFLLPESQIKPTCEETMLAVKYIANHVLNNLY", "length": 416 }, "evidence": [ { "id": "HGNC:2299", "url": "https://alliancegenome.org/gene/HGNC:2299#orthology", "database": "AGR" }, { "id": "HGNC:2298", "url": "https://alliancegenome.org/gene/HGNC:2298#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-1132", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1132#orthology", "database": "AGR" }, { "id": "RGD:2390", "url": "https://alliancegenome.org/gene/RGD:2390#orthology", "database": "AGR" }, { "id": "RGD:2391", "url": "https://alliancegenome.org/gene/RGD:2391#orthology", "database": "AGR" }, { "id": "FB:FBgn0035791", "url": "https://alliancegenome.org/gene/FB:FBgn0035791#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P00731-1", "protein_name": "Carboxypeptidase A1", "gene_name": "Cpa1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKRLLILSLLLEAVCGNENFVGHQVLRISAADEAQVQKVKELEDLEHLQLDFWRDAARAGIPIDVRVPFPSIQSVKAFLEYHGISYEIMIEDVQLLLDEEKQQMSAFQARALSTDSFNYATYHTLDEIYEFMDLLVAEHPQLVSKIQIGNTFEGRPIHVLKFSTGGTNRPAIWIDTGIHSREWVTQASGVWFAKKITKDYGQDPTFTAVLDNMDIFLEIVTNPDGFAYTHKTNRMWRKTRSHTQGSLCVGVDPNRNWDAGFGMAGASSNPCSETYRGKFPNSEVEVKSIVDFVTSHGNIKAFISIHSYSQLLLYPYGYTSEPAPDQAELDQLAKSAVTALTSLHGTKFKYGSIIDTIYQASGSTIDWTYSQGIKYSFTFELRDTGLRGFLLPASQIIPTAEETWLALLTIMDHTVKHPY", "length": 419 }, "evidence": [ { "id": "MGI:88478", "url": "https://alliancegenome.org/gene/MGI:88478#orthology", "database": "AGR" }, { "id": "HGNC:2296", "url": "https://alliancegenome.org/gene/HGNC:2296#orthology", "database": "AGR" }, { "id": "RGD:2388", "url": "https://alliancegenome.org/gene/RGD:2388#orthology", "database": "AGR" }, { "id": "FB:FBgn0035791", "url": "https://alliancegenome.org/gene/FB:FBgn0035791#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P15085-1", "protein_name": "Carboxypeptidase A1", "gene_name": "CPA1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRGLLVLSVLLGAVFGKEDFVGHQVLRISVADEAQVQKVKELEDLEHLQLDFWRGPAHPGSPIDVRVPFPSIQAVKIFLESHGISYETMIEDVQSLLDEEQEQMFAFRSRARSTDTFNYATYHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTGGSKRPAIWIDTGIHSREWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWRKTRSHTAGSLCIGVDPNRNWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIVDFVKDHGNIKAFISIHSYSQLLMYPYGYKTEPVPDQDELDQLSKAAVTALASLYGTKFNYGSIIKAIYQASGSTIDWTYSQGIKYSFTFELRDTGRYGFLLPASQIIPTAKETWLALLTIMEHTLNHPY", "length": 419 }, "evidence": [ { "id": "MGI:88478", "url": "https://alliancegenome.org/gene/MGI:88478#orthology", "database": "AGR" }, { "id": "HGNC:2296", "url": "https://alliancegenome.org/gene/HGNC:2296#orthology", "database": "AGR" }, { "id": "RGD:2388", "url": "https://alliancegenome.org/gene/RGD:2388#orthology", "database": "AGR" }, { "id": "FB:FBgn0035791", "url": "https://alliancegenome.org/gene/FB:FBgn0035791#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P15086-1", "protein_name": "Carboxypeptidase B", "gene_name": "CPB1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLALLVLVTVALASAHHGGEHFEGEKVFRVNVEDENHINIIRELASTTQIDFWKPDSVTQIKPHSTVDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVVEAQFDSRVRATGHSYEKYNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNKPAIFMDCGFHAREWISPAFCQWFVREAVRTYGREIQVTELLDKLDFYVLPVLNIDGYIYTWTKSRFWRKTRSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNKLSSIKAYLTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKELASLHGTKYTYGPGATTIYPAAGGSDDWAYDQGIRYSFTFELRDTGRYGFLLPESQIRATCEETFLAIKYVASYVLEHLY", "length": 417 }, "evidence": [ { "id": "HGNC:2299", "url": "https://alliancegenome.org/gene/HGNC:2299#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-1132", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1132#orthology", "database": "AGR" }, { "id": "RGD:2391", "url": "https://alliancegenome.org/gene/RGD:2391#orthology", "database": "AGR" }, { "id": "FB:FBgn0035791", "url": "https://alliancegenome.org/gene/FB:FBgn0035791#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P15088-1", "protein_name": "Mast cell carboxypeptidase A", "gene_name": "CPA3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRLILPVGLIATTLAIAPVRFDREKVFRVKPQDEKQADIIKDLAKTNELDFWYPGATHHVAANMMVDFRVSEKESQAIQSALDQNKMHYEILIHDLQEEIEKQFDVKEDIPGRHSYAKYNNWEKIVAWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKIGEKNERRKAIFTDCGIHAREWVSPAFCQWFVYQATKTYGRNKIMTKLLDRMNFYILPVFNVDGYIWSWTKNRMWRKNRSKNQNSKCIGTDLNRNFNASWNSIPNTNDPCADNYRGSAPESEKETKAVTNFIRSHLNEIKVYITFHSYSQMLLFPYGYTSKLPPNHEDLAKVAKIGTDVLSTRYETRYIYGPIESTIYPISGSSLDWAYDLGIKHTFAFELRDKGKFGFLLPESRIKPTCRETMLAVKFIAKYILKHTS", "length": 417 }, "evidence": [ { "id": "MGI:88479", "url": "https://alliancegenome.org/gene/MGI:88479#orthology", "database": "AGR" }, { "id": "HGNC:2298", "url": "https://alliancegenome.org/gene/HGNC:2298#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-1132", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1132#orthology", "database": "AGR" }, { "id": "RGD:2390", "url": "https://alliancegenome.org/gene/RGD:2390#orthology", "database": "AGR" }, { "id": "FB:FBgn0035791", "url": "https://alliancegenome.org/gene/FB:FBgn0035791#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P15089-1", "protein_name": "Mast cell carboxypeptidase A", "gene_name": "Cpa3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRFFLLMAVIYTTLAIAPVHFDREKVFRVKLQNEKHASVLKNLTQSIELDFWYPDAIHDIAVNMTVDFRVSEKESQTIQSTLEQHKIHYEILIHDLQEEIEKQFDVKDEIAGRHSYAKYNDWDKIVSWTEKMLEKHPEMVSRIKIGSTVEDNPLYVLKIGKKDGERKAIFMDCGIHAREWISPAFCQWFVYQATKSYGKNKIMTKLLDRMNFYVLPVFNVDGYIWSWTQDRMWRKNRSRNQNSTCIGTDLNRNFDVSWDSSPNTNKPCLNVYRGPAPESEKETKAVTNFIRSHLNSIKAYITFHSYSQMLLIPYGYTFKLPPNHQDLLKVARIATDALSTRYETRYIYGPIASTIYKTSGSSLDWVYDLGIKHTFAFELRDKGKSGFLLPESRIKPTCKETMLSVKFIAKYILKNTS", "length": 417 }, "evidence": [ { "id": "MGI:88479", "url": "https://alliancegenome.org/gene/MGI:88479#orthology", "database": "AGR" }, { "id": "HGNC:2298", "url": "https://alliancegenome.org/gene/HGNC:2298#orthology", "database": "AGR" }, { "id": "RGD:2390", "url": "https://alliancegenome.org/gene/RGD:2390#orthology", "database": "AGR" }, { "id": "FB:FBgn0035791", "url": "https://alliancegenome.org/gene/FB:FBgn0035791#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P19223-1", "protein_name": "Carboxypeptidase B", "gene_name": "Cpb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLLLLALVSVALAHASEEHFDGNRVYRVSVHGEDHVNLIQELANTKEIDFWKPDSATQVKPLTTVDFHVKAEDVADVENFLEENEVHYEVLISNVRNALESQFDSHTRASGHSYTKYNKWETIEAWIQQVATDNPDLVTQSVIGTTFEGRNMYVLKIGKTRPNKPAIFIDCGFHAREWISPAFCQWFVREAVRTYNQEIHMKQLLDELDFYVLPVVNIDGYVYTWTKDRMWRKTRSTMAGSSCLGVRPNRNFNAGWCEVGASRSPCSETYCGPAPESEKETKALADFIRNNLSTIKAYLTIHSYSQMMLYPYSYDYKLPENYEELNALVKGAAKELATLHGTKYTYGPGATTIYPAAGGSDDWSYDQGIKYSFTFELRDTGFFGFLLPESQIRQTCEETMLAVKYIANYVREHLY", "length": 415 }, "evidence": [ { "id": "HGNC:2299", "url": "https://alliancegenome.org/gene/HGNC:2299#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-1132", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1132#orthology", "database": "AGR" }, { "id": "RGD:2391", "url": "https://alliancegenome.org/gene/RGD:2391#orthology", "database": "AGR" }, { "id": "FB:FBgn0035791", "url": "https://alliancegenome.org/gene/FB:FBgn0035791#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P21961-1", "protein_name": "Mast cell carboxypeptidase A", "gene_name": "Cpa3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LMGVIYSTLAIAPVQFDREKVFRVKLQDEKQASILKNLTQTIELDFWYPDAIHDIAVNMTVDFRVTEKESQTIQSTLEQHKMDYEILINDLQEEIDKQFDVKEEIAGRHSYAKYNDWNKIVSWTEKMVEKHPEMVSRIKIGSTVEDNPLYVLKIGRKDGERKAIFMDCGIHAREWVSPAFCQWFVYQAAKSYGKNKIMTKLLDRMNFYVLPVFNVDGYIWSWTKDRMWRKNRSKNPNSTCIGTDLNRNFDVSWDSSPNTDNPCLSVYRGPAPESEKETKAVTNFIRSHLNSIKAYITFHSYSQMLLFPYGYTIKLPPNHQDLLKVARIATDVLSSRYETRYIYGPIASTIYKTSGSSLDWAYDLGIKHTFAFELRDKGKSGFLLPESRIKPTCKETMLSVKFIAKYILKHTS", "length": 412 }, "evidence": [ { "id": "MGI:88479", "url": "https://alliancegenome.org/gene/MGI:88479#orthology", "database": "AGR" }, { "id": "HGNC:2298", "url": "https://alliancegenome.org/gene/HGNC:2298#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-1132", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1132#orthology", "database": "AGR" }, { "id": "RGD:2390", "url": "https://alliancegenome.org/gene/RGD:2390#orthology", "database": "AGR" }, { "id": "FB:FBgn0035791", "url": "https://alliancegenome.org/gene/FB:FBgn0035791#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P38836-1", "protein_name": "Inactive metallocarboxypeptidase ECM14", "gene_name": "ECM14", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLHMNSLWGCFLFVLLAVTGAVQGLQEDYSEYAVYRFTSDNYSTLVRDVIAPLTDDYDVWTRSNNFIDIKLPKEIGEQINDGQVIIDNMNELIQNTLPTSQMMAREQAVFENDYDFFFNEYRDLDTIYMWLDLLERSFPSLVAVEHLGRTFEGRELKALHISGNKPESNPEKKTIVITGGIHAREWISVSTVCWALYQLLNRYGSSKKETKYLDDLDFLVIPVFNPDGYAYTWSHDRLWRKNRQRTHVPQCLGIDIDHSFGFQWEKAHTHACSEEYSGETPFEAWEASAWYKYINETKGDYKIYGYIDMHSYSQEILYPYAYSCDALPRDLENLLELSYGLSKAIRSKSGRNYDVISACKDRGSDIFPGLGAGSALDFMYHHRAHWAFQLKLRDTGNHGFLLPPENIKPVGKETYAALKYFCDFLLDPEI", "length": 430 }, "evidence": [ { "id": "MGI:3045348", "url": "https://alliancegenome.org/gene/MGI:3045348#orthology", "database": "AGR" }, { "id": "MGI:1891837", "url": "https://alliancegenome.org/gene/MGI:1891837#orthology", "database": "AGR" }, { "id": "MGI:88478", "url": "https://alliancegenome.org/gene/MGI:88478#orthology", "database": "AGR" }, { "id": "MGI:1921899", "url": "https://alliancegenome.org/gene/MGI:1921899#orthology", "database": "AGR" }, { "id": "MGI:88479", "url": "https://alliancegenome.org/gene/MGI:88479#orthology", "database": "AGR" }, { "id": "HGNC:15722", "url": "https://alliancegenome.org/gene/HGNC:15722#orthology", "database": "AGR" }, { "id": "HGNC:2299", "url": "https://alliancegenome.org/gene/HGNC:2299#orthology", "database": "AGR" }, { "id": "HGNC:17245", "url": "https://alliancegenome.org/gene/HGNC:17245#orthology", "database": "AGR" }, { "id": "HGNC:21011", "url": "https://alliancegenome.org/gene/HGNC:21011#orthology", "database": "AGR" }, { "id": "HGNC:2300", "url": "https://alliancegenome.org/gene/HGNC:2300#orthology", "database": "AGR" }, { "id": "HGNC:2298", "url": "https://alliancegenome.org/gene/HGNC:2298#orthology", "database": "AGR" }, { "id": "HGNC:2296", "url": "https://alliancegenome.org/gene/HGNC:2296#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070619-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070619-6#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-1132", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1132#orthology", "database": "AGR" }, { "id": "RGD:2390", "url": "https://alliancegenome.org/gene/RGD:2390#orthology", "database": "AGR" }, { "id": "RGD:71035", "url": "https://alliancegenome.org/gene/RGD:71035#orthology", "database": "AGR" }, { "id": "RGD:1311764", "url": "https://alliancegenome.org/gene/RGD:1311764#orthology", "database": "AGR" }, { "id": "RGD:2388", "url": "https://alliancegenome.org/gene/RGD:2388#orthology", "database": "AGR" }, { "id": "RGD:2391", "url": "https://alliancegenome.org/gene/RGD:2391#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q0E9F9-1", "protein_name": "Zinc carboxypeptidase A 1", "gene_name": "Dmel\\CG2915", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGNKIINMPAARIGTQWLVILCVAMAASGTNLDSGICPVAGDSGCRGNPPDQARYDNYRIYNVEFENQEQIELFQKLEEQSDSLTFIGHAREVGQKLSILVAAHRVADIADLLKTYKVKHRVLTYNFQEKIDRNLAEVQPESIDASQLDWQHFFHLKTIYEWLDKMVEKYPNRVTVLDMGSSTQGNAIKGVKLTSNANNKAIFIESGIHAREWISPAAATYIINQLLTSQDPKVQQLAQDYNWIIFPCVNPDGYKYTFEHDRMWRKNRQLFGTCRGVDLNRNYPDHWNSTGSSSDPTRYDFAGPSAGSELETKRLIDFIRANAGKEQIKTYIALHSYSQMLMFPYGYTKERVSNYDDLQEFGKKASAAIKAENGRDYVSGSLFETIYPSSGGSMDWAHSEAGIPIAYTFELRGPPDSQDLFILPAVEIQPTASEAFTAIRAIVEAAAEKGYYK", "length": 453 }, "evidence": [ { "id": "MGI:3045348", "url": "https://alliancegenome.org/gene/MGI:3045348#orthology", "database": "AGR" }, { "id": "MGI:1891837", "url": "https://alliancegenome.org/gene/MGI:1891837#orthology", "database": "AGR" }, { "id": "MGI:88478", "url": "https://alliancegenome.org/gene/MGI:88478#orthology", "database": "AGR" }, { "id": "MGI:1921899", "url": "https://alliancegenome.org/gene/MGI:1921899#orthology", "database": "AGR" }, { "id": "MGI:88479", "url": "https://alliancegenome.org/gene/MGI:88479#orthology", "database": "AGR" }, { "id": "HGNC:15722", "url": "https://alliancegenome.org/gene/HGNC:15722#orthology", "database": "AGR" }, { "id": "HGNC:2299", "url": "https://alliancegenome.org/gene/HGNC:2299#orthology", "database": "AGR" }, { "id": "HGNC:17245", "url": "https://alliancegenome.org/gene/HGNC:17245#orthology", "database": "AGR" }, { "id": "HGNC:2300", "url": "https://alliancegenome.org/gene/HGNC:2300#orthology", "database": "AGR" }, { "id": "HGNC:2298", "url": "https://alliancegenome.org/gene/HGNC:2298#orthology", "database": "AGR" }, { "id": "HGNC:2296", "url": "https://alliancegenome.org/gene/HGNC:2296#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070619-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070619-6#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-1132", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1132#orthology", "database": "AGR" }, { "id": "RGD:2390", "url": "https://alliancegenome.org/gene/RGD:2390#orthology", "database": "AGR" }, { "id": "RGD:71035", "url": "https://alliancegenome.org/gene/RGD:71035#orthology", "database": "AGR" }, { "id": "RGD:1311764", "url": "https://alliancegenome.org/gene/RGD:1311764#orthology", "database": "AGR" }, { "id": "RGD:2388", "url": "https://alliancegenome.org/gene/RGD:2388#orthology", "database": "AGR" }, { "id": "RGD:2391", "url": "https://alliancegenome.org/gene/RGD:2391#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q5U901-1", "protein_name": "Carboxypeptidase A6", "gene_name": "Cpa6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNFLGNPRSHTAAFLPVCWLLLNILKPGHCHSYDNRYAGDKVIRLIPKSEEEALALKNIYHQLKVDLWQPSSISYVSEGTITDVHISQNASRTLLAFLQETHIYYKVLIEDLQKAVENENSLQTQRNRRSLSEYNYEVYHSLEDIQSWLHHLNQTQPGLVRVFSIGRSYEGRPLFIMQLGRKSRAYKRAVWIDCGIHAREWIGPAFCQWFVREAILTYKTDPAMKKMLNHLYFYIMPVFNVDGYHFSWTHDRFWRKTRSRDSKFRCRGVDANRNWKVKWCDEGASAHPCDDTYCGPFPESEPEVKAVANFLRKHRKRIRAYLSFHAYAQMLLYPYSYKYATIPNFSCVEFAAHKAVKALRSVHGIRYRHGPASQTLYVSSGNSMDWAYKNGIPYAFAFELRDTGHFGFLLPEMLIKPTCTETMLAVKNITMHLLKKCP", "length": 438 }, "evidence": [ { "id": "MGI:3045348", "url": "https://alliancegenome.org/gene/MGI:3045348#orthology", "database": "AGR" }, { "id": "HGNC:17245", "url": "https://alliancegenome.org/gene/HGNC:17245#orthology", "database": "AGR" }, { "id": "RGD:1311764", "url": "https://alliancegenome.org/gene/RGD:1311764#orthology", "database": "AGR" }, { "id": "FB:FBgn0035791", "url": "https://alliancegenome.org/gene/FB:FBgn0035791#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TPZ8-1", "protein_name": "Carboxypeptidase A1", "gene_name": "Cpa1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKRLLVLSVLLAAVFGNENFVGHQVLRISATDEAQVQKVRELEELEHLKLDFWRDPARAGLPIDVRVPFPTIQSVKAFLEYHDISYEIMIEDVQSLLDEEKQQMSAFQARALSTDAFNYATYHTLDEIYEFMDLLVTEHPQLVSKIQIGSTFEGRPINVLKFSTGGTNRPAIWIDTGIHSREWVTQASGVWFAKKITKDYGQEPTLTAILDNMDIFLEIVTNPDGFVYTHKTNRMWRKTRSHTEGSLCVGVDPNRNWDAAFGMPGASSNPCSETYRGKFPNSEVEVKSIVDFVTSHGNIKAFISIHSYSQLLLYPYGYTSEPAPDKEELDQLAKSAVTALTSLHGTKFKYGSIIDTIYQASGSTIDWTYSQGIKYSFTFELRDTGLRGFLLPASQIIPTAEETWLALLTIMDHTVKHPY", "length": 419 }, "evidence": [ { "id": "MGI:88478", "url": "https://alliancegenome.org/gene/MGI:88478#orthology", "database": "AGR" }, { "id": "HGNC:2296", "url": "https://alliancegenome.org/gene/HGNC:2296#orthology", "database": "AGR" }, { "id": "RGD:2388", "url": "https://alliancegenome.org/gene/RGD:2388#orthology", "database": "AGR" }, { "id": "FB:FBgn0035791", "url": "https://alliancegenome.org/gene/FB:FBgn0035791#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IVL8-1", "protein_name": "Carboxypeptidase O", "gene_name": "CPO", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKPLLETLYLLGMLVPGGLGYDRSLAQHRQEIVDKSVSPWSLETYSYNIYHPMGEIYEWMREISEKYKEVVTQHFLGVTYETHPMYYLKISQPSGNPKKIIWMDCGIHAREWIAPAFCQWFVKEILQNHKDNSSIRKLLRNLDFYVLPVLNIDGYIYTWTTDRLWRKSRSPHNNGTCFGTDLNRNFNASWCSIGASRNCQDQTFCGTGPVSEPETKAVASFIESKKDDILCFLTMHSYGQLILTPYGYTKNKSSNHPEMIQVGQKAANALKAKYGTNYRVGSSADILYASSGSSRDWARDIGIPFSYTFELRDSGTYGFVLPEAQIQPTCEETMEAVLSVLDDVYAKHWHSDSAGRVTSATMLLGLLVSCMSLL", "length": 374 }, "evidence": [ { "id": "HGNC:21011", "url": "https://alliancegenome.org/gene/HGNC:21011#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070619-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070619-6#orthology", "database": "AGR" }, { "id": "FB:FBgn0035791", "url": "https://alliancegenome.org/gene/FB:FBgn0035791#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8N4T0-1", "protein_name": "Carboxypeptidase A6", "gene_name": "CPA6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKCLGKRRGQAAAFLPLCWLFLKILQPGHSHLYNNRYAGDKVIRFIPKTEEEAYALKKISYQLKVDLWQPSSISYVSEGTVTDVHIPQNGSRALLAFLQEANIQYKVLIEDLQKTLEKGSSLHTQRNRRSLSGYNYEVYHSLEEIQNWMHHLNKTHSGLIHMFSIGRSYEGRSLFILKLGRRSRLKRAVWIDCGIHAREWIGPAFCQWFVKEALLTYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWRKTRSRNSRFRCRGVDANRNWKVKWCDEGASMHPCDDTYCGPFPESEPEVKAVANFLRKHRKHIRAYLSFHAYAQMLLYPYSYKYATIPNFRCVESAAYKAVNALQSVYGVRYRYGPASTTLYVSSGSSMDWAYKNGIPYAFAFELRDTGYFGFLLPEMLIKPTCTETMLAVKNITMHLLKKCP", "length": 437 }, "evidence": [ { "id": "MGI:3045348", "url": "https://alliancegenome.org/gene/MGI:3045348#orthology", "database": "AGR" }, { "id": "HGNC:17245", "url": "https://alliancegenome.org/gene/HGNC:17245#orthology", "database": "AGR" }, { "id": "RGD:1311764", "url": "https://alliancegenome.org/gene/RGD:1311764#orthology", "database": "AGR" }, { "id": "FB:FBgn0035791", "url": "https://alliancegenome.org/gene/FB:FBgn0035791#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R4H4-1", "protein_name": "Carboxypeptidase A5", "gene_name": "Cpa5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQGTQRGGLVPGLSPLDRRTLLFCNFILAVAWGQVNFTGDQVLRVLAKNEKQLSLLRDLETQKPQKVDFWRGPARPSLPVDMRVPFSELPSVKAYLKSHGLAYSIMIKDIQVLLDEERDAMAKSRRLERSTNSFSYSSYHTLDEIYSWIDNFVAEHSNLVSKIHIGKSFENRSILVLKFSTGGPNRPAIWIDTGIHSREWITHATGIWISQKIVNAYGKDHVLKRILNTMDIFIEIVTNPDGFAFTHSMNRLWRKNKSSQPGIFCIGVDLNRNWKAGFGGNGSNKNPCSETYRGPAPESEPEVAAIVDFITGHGNFKAMISIHSYSQMVMYPYGHSLEPVPNHEELFNLAKDAVKALNKVHGIQYIFGSISTTLYSASGISVDWAYDSGIKYAFSFELRDTGQYGFLLPASQIVPTAEETWMALQTIMKHTLNHPY", "length": 436 }, "evidence": [ { "id": "MGI:1921899", "url": "https://alliancegenome.org/gene/MGI:1921899#orthology", "database": "AGR" }, { "id": "HGNC:15722", "url": "https://alliancegenome.org/gene/HGNC:15722#orthology", "database": "AGR" }, { "id": "FB:FBgn0035791", "url": "https://alliancegenome.org/gene/FB:FBgn0035791#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WXQ8-1", "protein_name": "Carboxypeptidase A5", "gene_name": "CPA5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQGTPGGGTRPGPSPVDRRTLLVFSFILAAALGQMNFTGDQVLRVLAKDEKQLSLLGDLEGLKPQKVDFWRGPARPSLPVDMRVPFSELKDIKAYLESHGLAYSIMIKDIQVLLDEERQAMAKSRRLERSTNSFSYSSYHTLEEIYSWIDNFVMEHSDIVSKIQIGNSFENQSILVLKFSTGGSRHPAIWIDTGIHSREWITHATGIWTANKIVSDYGKDRVLTDILNAMDIFIELVTNPDGFAFTHSMNRLWRKNKSIRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETYHGPSPQSEPEVAAIVNFITAHGNFKALISIHSYSQMLMYPYGRLLEPVSNQRELYDLAKDAVEALYKVHGIEYIFGSISTTLYVASGITVDWAYDSGIKYAFSFELRDTGQYGFLLPATQIIPTAQETWMALRTIMEHTLNHPY", "length": 436 }, "evidence": [ { "id": "MGI:1921899", "url": "https://alliancegenome.org/gene/MGI:1921899#orthology", "database": "AGR" }, { "id": "HGNC:15722", "url": "https://alliancegenome.org/gene/HGNC:15722#orthology", "database": "AGR" }, { "id": "FB:FBgn0035791", "url": "https://alliancegenome.org/gene/FB:FBgn0035791#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q96IY4-1", "protein_name": "Carboxypeptidase B2", "gene_name": "CPB2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKLCSLAVLVPIVLFCEQHVFAFQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTADLIVKKKQVHFFVNASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYYEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKISKNTRYTHGHGSETLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVIRNV", "length": 423 }, "evidence": [ { "id": "MGI:1891837", "url": "https://alliancegenome.org/gene/MGI:1891837#orthology", "database": "AGR" }, { "id": "HGNC:2300", "url": "https://alliancegenome.org/gene/HGNC:2300#orthology", "database": "AGR" }, { "id": "RGD:71035", "url": "https://alliancegenome.org/gene/RGD:71035#orthology", "database": "AGR" }, { "id": "FB:FBgn0035791", "url": "https://alliancegenome.org/gene/FB:FBgn0035791#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9EQV9-1", "protein_name": "Carboxypeptidase B2", "gene_name": "Cpb2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKLYGLGVLVAIILYEKHGLAFQSGHVLSALPRTSRQVQLLQNLTTTYEVVLWQPVTAEFIEKKKEVHFFVNASDVNSVKAYLNASRIPFNVLMNNVEDLIQQQTSNDTVSPRASSSYYEQYHSLNEIYSWIEVITEQHPDMLQKIYIGSSYEKYPLYVLKVSGKEHRVKNAIWIDCGIHAREWISPAFCLWFIGYVTQFHGKENTYTRLLRHVDFYIMPVMNVDGYDYTWKKNRMWRKNRSVHMNNRCVGTDLNRNFASKHWCEKGASSFSCSETYCGLYPESEPEVKAVADFLRRNINHIKAYISMHSYSQQILFPYSYNRSKSKDHEELSLVASEAVRAIESINKNTRYTHGSGSESLYLAPGGSDDWIYDLGIKYSFTIELRDTGRYGFLLPERFIKPTCAEALAAVSKIAWHVIRNS", "length": 422 }, "evidence": [ { "id": "MGI:1891837", "url": "https://alliancegenome.org/gene/MGI:1891837#orthology", "database": "AGR" }, { "id": "HGNC:2300", "url": "https://alliancegenome.org/gene/HGNC:2300#orthology", "database": "AGR" }, { "id": "RGD:71035", "url": "https://alliancegenome.org/gene/RGD:71035#orthology", "database": "AGR" }, { "id": "FB:FBgn0035791", "url": "https://alliancegenome.org/gene/FB:FBgn0035791#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9JHH6-1", "protein_name": "Carboxypeptidase B2", "gene_name": "Cpb2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLHGLGILVAIILYEQHGFAFQSGQVLSALPRTSRQVQLLQNLTTTYEVVLWQPVTAEFIEKKKEVHFFVNASDVDSVKAHLNVSRIPFNVLMNNVEDLIEQQTFNDTVSPRASASYYEQYHSLNEIYSWIEVITEQHPDMLQKIYIGSSFEKYPLYVLKVSGKEQRIKNAIWIDCGIHAREWISPAFCLWFIGYVTQFHGKENLYTRLLRHVDFYIMPVMNVDGYDYTWKKNRMWRKNRSAHKNNRCVGTDLNRNFASKHWCEKGASSSSCSETYCGLYPESEPEVKAVADFLRRNIDHIKAYISMHSYSQQILFPYSYNRSKSKDHEELSLVASEAVRAIESINKNTRYTHGSGSESLYLAPGGSDDWIYDLGIKYSFTIELRDTGRYGFLLPERYIKPTCAEALAAISKIVWHVIRNT", "length": 422 }, "evidence": [ { "id": "MGI:1891837", "url": "https://alliancegenome.org/gene/MGI:1891837#orthology", "database": "AGR" }, { "id": "HGNC:2300", "url": "https://alliancegenome.org/gene/HGNC:2300#orthology", "database": "AGR" }, { "id": "RGD:71035", "url": "https://alliancegenome.org/gene/RGD:71035#orthology", "database": "AGR" }, { "id": "FB:FBgn0035791", "url": "https://alliancegenome.org/gene/FB:FBgn0035791#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VCM8-1", "protein_name": "Zinc carboxypeptidase A 1", "gene_name": "Dmel\\CG4408", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MYACQSALQENEMEIFYTDFKLRRIKMLPKGGTPKTWLLLLLVSSVCVIQESKASSFCTKADQCALDEEIKTAADSVQARYDHTRIYQVELASEEHVRLFQALEQASDSCSFMGHARQPGQKLTIMVTGAKVADFDDLVHSYNVTHRVLNYNFQALIDANYLEVAPEDTKPEEFDWKRYHPLESINAWLKKLAETHPEVLLVELGVSAQGRPILGVQIAFDNENRTTVFVESGIHAREWIAPATATYIIDQLVNSKDSAVQALARSQRWYIFPTVNPDGYQYTFKGDRMWRKNRALFGICRGVDLNRNFPFHWNVTGASGDPCRYDYSGPSAASEVETQRMIEFIRHRVESERIRTFISLHSYSQMIMFPYGHSAERVDNYHDLTDIGKLAANKIKDVSGRIYKSGSIYETIYPSSGGSKDWAHGQLKIPITFSYELRGPADSEDLFILSAKEIEPTAAEAFASIQTIVQEAGKRGYYQ", "length": 479 }, "evidence": [ { "id": "MGI:3045348", "url": "https://alliancegenome.org/gene/MGI:3045348#orthology", "database": "AGR" }, { "id": "MGI:1891837", "url": "https://alliancegenome.org/gene/MGI:1891837#orthology", "database": "AGR" }, { "id": "MGI:88478", "url": "https://alliancegenome.org/gene/MGI:88478#orthology", "database": "AGR" }, { "id": "MGI:1921899", "url": "https://alliancegenome.org/gene/MGI:1921899#orthology", "database": "AGR" }, { "id": "MGI:88479", "url": "https://alliancegenome.org/gene/MGI:88479#orthology", "database": "AGR" }, { "id": "HGNC:15722", "url": "https://alliancegenome.org/gene/HGNC:15722#orthology", "database": "AGR" }, { "id": "HGNC:2299", "url": "https://alliancegenome.org/gene/HGNC:2299#orthology", "database": "AGR" }, { "id": "HGNC:17245", "url": "https://alliancegenome.org/gene/HGNC:17245#orthology", "database": "AGR" }, { "id": "HGNC:2300", "url": "https://alliancegenome.org/gene/HGNC:2300#orthology", "database": "AGR" }, { "id": "HGNC:2298", "url": "https://alliancegenome.org/gene/HGNC:2298#orthology", "database": "AGR" }, { "id": "HGNC:2296", "url": "https://alliancegenome.org/gene/HGNC:2296#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070619-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070619-6#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-1132", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1132#orthology", "database": "AGR" }, { "id": "RGD:2390", "url": "https://alliancegenome.org/gene/RGD:2390#orthology", "database": "AGR" }, { "id": "RGD:71035", "url": "https://alliancegenome.org/gene/RGD:71035#orthology", "database": "AGR" }, { "id": "RGD:1311764", "url": "https://alliancegenome.org/gene/RGD:1311764#orthology", "database": "AGR" }, { "id": "RGD:2388", "url": "https://alliancegenome.org/gene/RGD:2388#orthology", "database": "AGR" }, { "id": "RGD:2391", "url": "https://alliancegenome.org/gene/RGD:2391#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VL86-1", "protein_name": "Zinc carboxypeptidase A 1", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSLNKCLLFALLAIVASASVSAERVRYDNYRMYKVNSENAKQLEVLKDLEGSSDSIMFLDGVHLVGADIQIIVAPHKVPDFLEILGKSEIKYELQSRDVQKSLDEIDEKVAIKGRATTAYNWAQYYELDDTYAWLQSLAQTNPGVVTLIEGGKTYQGRSILGVKITKGGETINGKAKPGIFLEAGIHAREWIAPAAATFIINQLLTSEVENIKELAENYTWYVLPHANPDGYVYTHTTNRLWRKTRTPYGSCFGADPNRNWGFHWNEVGASSSACSDTYAGPSAFSEIETLSLSKFIEGLKGKVQLYLSLHAYSQYLLYPYGHTSDLPDNVADFEKVFDASIAAVNKRYGTTYTGGNIYDAIYPAAGASVDWAYGTQDVRMAFCYELRPSSTSYLTGFKLPAEQIVPASEELLDSIVAMATEVKSLGYFD", "length": 430 }, "evidence": [ { "id": "MGI:3045348", "url": "https://alliancegenome.org/gene/MGI:3045348#orthology", "database": "AGR" }, { "id": "MGI:1891837", "url": "https://alliancegenome.org/gene/MGI:1891837#orthology", "database": "AGR" }, { "id": "MGI:88478", "url": "https://alliancegenome.org/gene/MGI:88478#orthology", "database": "AGR" }, { "id": "MGI:1921899", "url": "https://alliancegenome.org/gene/MGI:1921899#orthology", "database": "AGR" }, { "id": "MGI:88479", "url": "https://alliancegenome.org/gene/MGI:88479#orthology", "database": "AGR" }, { "id": "HGNC:15722", "url": "https://alliancegenome.org/gene/HGNC:15722#orthology", "database": "AGR" }, { "id": "HGNC:2299", "url": "https://alliancegenome.org/gene/HGNC:2299#orthology", "database": "AGR" }, { "id": "HGNC:17245", "url": "https://alliancegenome.org/gene/HGNC:17245#orthology", "database": "AGR" }, { "id": "HGNC:21011", "url": "https://alliancegenome.org/gene/HGNC:21011#orthology", "database": "AGR" }, { "id": "HGNC:2300", "url": "https://alliancegenome.org/gene/HGNC:2300#orthology", "database": "AGR" }, { "id": "HGNC:2298", "url": "https://alliancegenome.org/gene/HGNC:2298#orthology", "database": "AGR" }, { "id": "HGNC:2296", "url": "https://alliancegenome.org/gene/HGNC:2296#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070619-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070619-6#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-1132", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1132#orthology", "database": "AGR" }, { "id": "RGD:2390", "url": "https://alliancegenome.org/gene/RGD:2390#orthology", "database": "AGR" }, { "id": "RGD:71035", "url": "https://alliancegenome.org/gene/RGD:71035#orthology", "database": "AGR" }, { "id": "RGD:1311764", "url": "https://alliancegenome.org/gene/RGD:1311764#orthology", "database": "AGR" }, { "id": "RGD:2388", "url": "https://alliancegenome.org/gene/RGD:2388#orthology", "database": "AGR" }, { "id": "RGD:2391", "url": "https://alliancegenome.org/gene/RGD:2391#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VL87-1", "protein_name": "Peptidase M14 domain-containing protein", "gene_name": "Dmel\\CG4017", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKLLLLLLSVNILIFCLAERQRFDNYKVYRVSPVKANQLEGLRSLEANSEDALVLNNLHLGPTDFLVAPDFDGTFLKLVKDLDLSPELIDANAQTSLSLDIEPIADANRRSDDYSWSEYHELNDTHRWMQNLVGKYPDVVSVFVAGQSYEGRELLGLRINHNDGRAEKQSIFLEAGMHAREWIGPATATYFANELLSSQQQEIMNLARSYVWYILPHANPDGYVYTHKTNRMWRKTRSPQDKNCVGTDPNRNWDFHWREVGASSDPCSESYAGPKAFSEPEVQTLSQFLKSVPEPMFMFLSLHSFSQLLLYPYGHTSALPENHRQLEQIFNTAVGAMKRRYGTRYTGGNVYDAIYPAAGSSMDWAYGVLNVKYSFTYELRPSGYSFWTGFRLPAAQIIPTGQETTDSLVEMIKAAAQIEGYKIE", "length": 424 }, "evidence": [ { "id": "MGI:3045348", "url": "https://alliancegenome.org/gene/MGI:3045348#orthology", "database": "AGR" }, { "id": "MGI:1891837", "url": "https://alliancegenome.org/gene/MGI:1891837#orthology", "database": "AGR" }, { "id": "MGI:88478", "url": "https://alliancegenome.org/gene/MGI:88478#orthology", "database": "AGR" }, { "id": "MGI:1921899", "url": "https://alliancegenome.org/gene/MGI:1921899#orthology", "database": "AGR" }, { "id": "MGI:88479", "url": "https://alliancegenome.org/gene/MGI:88479#orthology", "database": "AGR" }, { "id": "HGNC:15722", "url": "https://alliancegenome.org/gene/HGNC:15722#orthology", "database": "AGR" }, { "id": "HGNC:2299", "url": "https://alliancegenome.org/gene/HGNC:2299#orthology", "database": "AGR" }, { "id": "HGNC:17245", "url": "https://alliancegenome.org/gene/HGNC:17245#orthology", "database": "AGR" }, { "id": "HGNC:2300", "url": "https://alliancegenome.org/gene/HGNC:2300#orthology", "database": "AGR" }, { "id": "HGNC:2298", "url": "https://alliancegenome.org/gene/HGNC:2298#orthology", "database": "AGR" }, { "id": "HGNC:2296", "url": "https://alliancegenome.org/gene/HGNC:2296#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070619-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070619-6#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-1132", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1132#orthology", "database": "AGR" }, { "id": "RGD:2390", "url": "https://alliancegenome.org/gene/RGD:2390#orthology", "database": "AGR" }, { "id": "RGD:71035", "url": "https://alliancegenome.org/gene/RGD:71035#orthology", "database": "AGR" }, { "id": "RGD:1311764", "url": "https://alliancegenome.org/gene/RGD:1311764#orthology", "database": "AGR" }, { "id": "RGD:2388", "url": "https://alliancegenome.org/gene/RGD:2388#orthology", "database": "AGR" }, { "id": "RGD:2391", "url": "https://alliancegenome.org/gene/RGD:2391#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VLZ1-1", "protein_name": "Peptidase M14 domain-containing protein", "gene_name": "Dmel\\CG7025", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MALNSLPIVLALVVLAQGASFGQDERLRYDNYSVYKVKFETQAQRSILRKLAEDRENFRLWHEAKDELHLMLSPGAFGELETEIQKTNVTAELFISNVQELIDSEEAANLKASRDGTFGWTKYNSLAEIYAWLDDILAAYPTITESFIVGQSYEGRTIRGIKISYKSNNPGVLIESNIHAREWITSATATWLINEFLTSTDELVRDLAENHDWYIVPVLNVDGFVYTHEKDRMWRKTRQPSEISSCIGADPNRNYDSHWMENEGASSNPCAEDYGGPKPFSEPEIQAMSEFVISIKDKINVLLAFHSYSQLLLSPYGHTKEEFPPNFDDMMEVAKAYGDAVESLPYGTVYRYGSAAGILYPASGATIDWAYNEQGVEISYTIEFRDTGRYGFILPPVHIIPNAEEALIGIAALLEKCKDLGYLGLKSAL", "length": 429 }, "evidence": [ { "id": "MGI:3045348", "url": "https://alliancegenome.org/gene/MGI:3045348#orthology", "database": "AGR" }, { "id": "MGI:1891837", "url": "https://alliancegenome.org/gene/MGI:1891837#orthology", "database": "AGR" }, { "id": "MGI:88478", "url": "https://alliancegenome.org/gene/MGI:88478#orthology", "database": "AGR" }, { "id": "MGI:1921899", "url": "https://alliancegenome.org/gene/MGI:1921899#orthology", "database": "AGR" }, { "id": "MGI:88479", "url": "https://alliancegenome.org/gene/MGI:88479#orthology", "database": "AGR" }, { "id": "HGNC:15722", "url": "https://alliancegenome.org/gene/HGNC:15722#orthology", "database": "AGR" }, { "id": "HGNC:2299", "url": "https://alliancegenome.org/gene/HGNC:2299#orthology", "database": "AGR" }, { "id": "HGNC:2296", "url": "https://alliancegenome.org/gene/HGNC:2296#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070619-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070619-6#orthology", "database": "AGR" }, { "id": "RGD:2390", "url": "https://alliancegenome.org/gene/RGD:2390#orthology", "database": "AGR" }, { "id": "RGD:71035", "url": "https://alliancegenome.org/gene/RGD:71035#orthology", "database": "AGR" }, { "id": "RGD:1311764", "url": "https://alliancegenome.org/gene/RGD:1311764#orthology", "database": "AGR" }, { "id": "RGD:2388", "url": "https://alliancegenome.org/gene/RGD:2388#orthology", "database": "AGR" }, { "id": "RGD:2391", "url": "https://alliancegenome.org/gene/RGD:2391#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VLZ2-1", "protein_name": "Zinc carboxypeptidase A 1", "gene_name": "Dmel\\CG18585", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRLLWLLATLVALTSAGILKDSPKERYDNFRVYKLTIQNKIQLAAIEKIGELTKKYNIWKEYDERSRQIDIMVSPGELNHFQELLKFNNISSELMIENVQERIDEEQVTPTADSATFGWTKYYELEEIEAWLDEILNAYPSVTEEFIVGKSYEGRTIRGIKISHKAGNPGIFIESNIHAREWITSASATWFINQLLTSEDADVRSLADNYDWHIIPVFNVDGFEYSHKKDRMWRKTRQPHATNACIGADANRNFDSYWLQNNGASDNPCSETFAGDNPESEPEAKALVEYLTKIQDQISVYISFHSYGQYLLSPYGHTNEEFPENYNDILTIGKAFADAIEALPYGTVYQYGSTADVLYVATGTSVDWVFNELGKKIGYTIEYRDKGRYGFILPPVQIIPNCEELMVGMLALIEKTKELGYL", "length": 422 }, "evidence": [ { "id": "MGI:3045348", "url": "https://alliancegenome.org/gene/MGI:3045348#orthology", "database": "AGR" }, { "id": "MGI:1891837", "url": "https://alliancegenome.org/gene/MGI:1891837#orthology", "database": "AGR" }, { "id": "MGI:88478", "url": "https://alliancegenome.org/gene/MGI:88478#orthology", "database": "AGR" }, { "id": "MGI:1921899", "url": "https://alliancegenome.org/gene/MGI:1921899#orthology", "database": "AGR" }, { "id": "MGI:88479", "url": "https://alliancegenome.org/gene/MGI:88479#orthology", "database": "AGR" }, { "id": "HGNC:15722", "url": "https://alliancegenome.org/gene/HGNC:15722#orthology", "database": "AGR" }, { "id": "HGNC:2299", "url": "https://alliancegenome.org/gene/HGNC:2299#orthology", "database": "AGR" }, { "id": "HGNC:2296", "url": "https://alliancegenome.org/gene/HGNC:2296#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070619-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070619-6#orthology", "database": "AGR" }, { "id": "RGD:2390", "url": "https://alliancegenome.org/gene/RGD:2390#orthology", "database": "AGR" }, { "id": "RGD:71035", "url": "https://alliancegenome.org/gene/RGD:71035#orthology", "database": "AGR" }, { "id": "RGD:1311764", "url": "https://alliancegenome.org/gene/RGD:1311764#orthology", "database": "AGR" }, { "id": "RGD:2388", "url": "https://alliancegenome.org/gene/RGD:2388#orthology", "database": "AGR" }, { "id": "RGD:2391", "url": "https://alliancegenome.org/gene/RGD:2391#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VRZ3-1", "protein_name": "Zinc carboxypeptidase A 1", "gene_name": "Dmel\\CG14820", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLLKILLVVGLFGLARSVEQVRYDNYKVYNVRIDDLEQFKLLHTQERSLKLSSWREARHLGESSDIMLPPEYQKTFESLLTKHNFTYNLKIDNVQTHIDAQRPKQRITSMEWTQFHTLEEIYAWLDVIEDRYPDIVTPFTIGNSYEGRPIRGVKISYKEGNPAVFIESNIHAREWITSATITYFIDELLVPRNPAVRDIAQNVDWYIIPVLNTDGFAYSHEVERLWRKSRLPSDPTGECIGTDLNRNFDYLWMLTGAESDPCSQLYAGPSPESDPEISQLTAYINNSIPEGTIKIYISLHSYGQYVLSPWGHTALEFPEHYPQMMHVAKGFSDALYRRYGTVFTYGSSATTLYEVSGSGKEWAYAVKNIKIHYTIELRDKGELGFVLPPEDIIPVAREVTEGFVGMIAAAREIDIL", "length": 416 }, "evidence": [ { "id": "MGI:3045348", "url": "https://alliancegenome.org/gene/MGI:3045348#orthology", "database": "AGR" }, { "id": "MGI:1891837", "url": "https://alliancegenome.org/gene/MGI:1891837#orthology", "database": "AGR" }, { "id": "MGI:88478", "url": "https://alliancegenome.org/gene/MGI:88478#orthology", "database": "AGR" }, { "id": "MGI:1921899", "url": "https://alliancegenome.org/gene/MGI:1921899#orthology", "database": "AGR" }, { "id": "MGI:88479", "url": "https://alliancegenome.org/gene/MGI:88479#orthology", "database": "AGR" }, { "id": "HGNC:15722", "url": "https://alliancegenome.org/gene/HGNC:15722#orthology", "database": "AGR" }, { "id": "HGNC:2299", "url": "https://alliancegenome.org/gene/HGNC:2299#orthology", "database": "AGR" }, { "id": "HGNC:2296", "url": "https://alliancegenome.org/gene/HGNC:2296#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070619-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070619-6#orthology", "database": "AGR" }, { "id": "RGD:2390", "url": "https://alliancegenome.org/gene/RGD:2390#orthology", "database": "AGR" }, { "id": "RGD:71035", "url": "https://alliancegenome.org/gene/RGD:71035#orthology", "database": "AGR" }, { "id": "RGD:1311764", "url": "https://alliancegenome.org/gene/RGD:1311764#orthology", "database": "AGR" }, { "id": "RGD:2388", "url": "https://alliancegenome.org/gene/RGD:2388#orthology", "database": "AGR" }, { "id": "RGD:2391", "url": "https://alliancegenome.org/gene/RGD:2391#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VS64-1", "protein_name": "Peptidase M14 domain-containing protein", "gene_name": "Dmel\\CG8563", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MWQGIVCSLALCLVGLAGLGIANNLAGYEGYTKYTVQHGDENAFKYMVDLQTNDAELDFWLLTRNSSVLTVSPRRKTQFEASLSSLGVSYEMQPLMELMAALQANSSFADDNYDGEYEECQQDECEQAERPRRRTRRQARGFFSHYPRYHEVLSFMSGLAARYPQFCRYESLGRSNEGRHIAALSISLNSRVRPRRVAYIQAATHGREWITTQTVLYLAYELLSNLRAFTRVLQDVEIFLVPLVNPDGYEYTHTTDRFWRKNRHRYAGHSCSGVDINRNFGNHWNYQGASQNLCSEVYSGTAPNSEPETSAVVRYLEFNRNRVKLSLDVHSFGKFIFYPYGYAKNTVPPTVGTLRSVALRAANQIGRYRGTRYTTGTSASILYEASGSLDDFAYGNLGIPLSYTLELPGDEFHVPAHDIIHVCKETFAGFIEFIRHVSLY", "length": 440 }, "evidence": [ { "id": "MGI:3045348", "url": "https://alliancegenome.org/gene/MGI:3045348#orthology", "database": "AGR" }, { "id": "MGI:1891837", "url": "https://alliancegenome.org/gene/MGI:1891837#orthology", "database": "AGR" }, { "id": "MGI:88478", "url": "https://alliancegenome.org/gene/MGI:88478#orthology", "database": "AGR" }, { "id": "MGI:1921899", "url": "https://alliancegenome.org/gene/MGI:1921899#orthology", "database": "AGR" }, { "id": "MGI:88479", "url": "https://alliancegenome.org/gene/MGI:88479#orthology", "database": "AGR" }, { "id": "HGNC:15722", "url": "https://alliancegenome.org/gene/HGNC:15722#orthology", "database": "AGR" }, { "id": "HGNC:17245", "url": "https://alliancegenome.org/gene/HGNC:17245#orthology", "database": "AGR" }, { "id": "HGNC:21011", "url": "https://alliancegenome.org/gene/HGNC:21011#orthology", "database": "AGR" }, { "id": "HGNC:2300", "url": "https://alliancegenome.org/gene/HGNC:2300#orthology", "database": "AGR" }, { "id": "HGNC:2298", "url": "https://alliancegenome.org/gene/HGNC:2298#orthology", "database": "AGR" }, { "id": "HGNC:2296", "url": "https://alliancegenome.org/gene/HGNC:2296#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070619-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070619-6#orthology", "database": "AGR" }, { "id": "RGD:2390", "url": "https://alliancegenome.org/gene/RGD:2390#orthology", "database": "AGR" }, { "id": "RGD:71035", "url": "https://alliancegenome.org/gene/RGD:71035#orthology", "database": "AGR" }, { "id": "RGD:1311764", "url": "https://alliancegenome.org/gene/RGD:1311764#orthology", "database": "AGR" }, { "id": "RGD:2388", "url": "https://alliancegenome.org/gene/RGD:2388#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VS65-1", "protein_name": "Peptidase M14 domain-containing protein", "gene_name": "CG18415", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRNYHLEYKVLIEDLAPLVHAQRAENLRKKLLIQWPHIDVLSAFYTHSEINDYLDSLLERFPKRVQVKQFGWSYERRPLKVLTITNGDGRRNKPVILIDGTVHAREWISPSMALYIIQQLLDNYGDNQELLQDYDWVIMPVVNADGYEYTHTDSRYWRKSRRPTSNPECIGTDINRNFGYEWGHDEGSSSDPCENIYRGERPFDQSESQVLRDVMLHYKGRLNFYLSLHSYGNYFLLPWGYTSDFPDTYQDMMSVADAGAKAIIYSTNGIYSYGSTYYVLYPTSGDTTDFAFGVVNATVAMTMELPAAGFQGFDPWISQIERLVTESWVGVRAMAAEVIRRYPS", "length": 344 }, "evidence": [ { "id": "MGI:3045348", "url": "https://alliancegenome.org/gene/MGI:3045348#orthology", "database": "AGR" }, { "id": "MGI:1891837", "url": "https://alliancegenome.org/gene/MGI:1891837#orthology", "database": "AGR" }, { "id": "MGI:88478", "url": "https://alliancegenome.org/gene/MGI:88478#orthology", "database": "AGR" }, { "id": "MGI:1921899", "url": "https://alliancegenome.org/gene/MGI:1921899#orthology", "database": "AGR" }, { "id": "MGI:88479", "url": "https://alliancegenome.org/gene/MGI:88479#orthology", "database": "AGR" }, { "id": "HGNC:15722", "url": "https://alliancegenome.org/gene/HGNC:15722#orthology", "database": "AGR" }, { "id": "HGNC:2299", "url": "https://alliancegenome.org/gene/HGNC:2299#orthology", "database": "AGR" }, { "id": "HGNC:17245", "url": "https://alliancegenome.org/gene/HGNC:17245#orthology", "database": "AGR" }, { "id": "HGNC:2300", "url": "https://alliancegenome.org/gene/HGNC:2300#orthology", "database": "AGR" }, { "id": "HGNC:2298", "url": "https://alliancegenome.org/gene/HGNC:2298#orthology", "database": "AGR" }, { "id": "HGNC:2296", "url": "https://alliancegenome.org/gene/HGNC:2296#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-1132", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1132#orthology", "database": "AGR" }, { "id": "RGD:2390", "url": "https://alliancegenome.org/gene/RGD:2390#orthology", "database": "AGR" }, { "id": "RGD:71035", "url": "https://alliancegenome.org/gene/RGD:71035#orthology", "database": "AGR" }, { "id": "RGD:1311764", "url": "https://alliancegenome.org/gene/RGD:1311764#orthology", "database": "AGR" }, { "id": "RGD:2388", "url": "https://alliancegenome.org/gene/RGD:2388#orthology", "database": "AGR" }, { "id": "RGD:2391", "url": "https://alliancegenome.org/gene/RGD:2391#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VS66-1", "protein_name": "Peptidase M14 domain-containing protein", "gene_name": "Dmel\\CG8562", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKFSLGLLVLFLGATLVAAEQDYEGYRIYEVIPSTADQADLLHQLSLQGYDFISETRLLGHPSRVIVSPAQLKHFQQLVEAEKMTLTLVNSNLGASIAEEFAQRQMQRLLAPITGKGRLSTERYYTHEEIINYIDDLAQRFPSRVFVKTVGWSYEQRVLKTITITNGDGKANKKVIFMDGGFHAREWISPAAVLYVIDQLVEQFEENAHLLKDYDWVILPLVNADGYEHTQTGTLARMWRKTRQPYTYAGQTCYGADPNRNFDFHWNEEGASSNPCADTYAGPTAFSEPETITVRDLMHSLADRGIMYLTLHSYGNYLLYPWGWTSDLPENWEDLDAVARTGAEAIENATGTVYTYGSSTNVLYIAAGASDDYGYYAGFNVSITMELPGAGSIGFNPPVTRIDEFVTETWIGIRAMAEKVIEMY", "length": 424 }, "evidence": [ { "id": "MGI:3045348", "url": "https://alliancegenome.org/gene/MGI:3045348#orthology", "database": "AGR" }, { "id": "MGI:1891837", "url": "https://alliancegenome.org/gene/MGI:1891837#orthology", "database": "AGR" }, { "id": "MGI:88478", "url": "https://alliancegenome.org/gene/MGI:88478#orthology", "database": "AGR" }, { "id": "MGI:1921899", "url": "https://alliancegenome.org/gene/MGI:1921899#orthology", "database": "AGR" }, { "id": "MGI:88479", "url": "https://alliancegenome.org/gene/MGI:88479#orthology", "database": "AGR" }, { "id": "HGNC:15722", "url": "https://alliancegenome.org/gene/HGNC:15722#orthology", "database": "AGR" }, { "id": "HGNC:2299", "url": "https://alliancegenome.org/gene/HGNC:2299#orthology", "database": "AGR" }, { "id": "HGNC:17245", "url": "https://alliancegenome.org/gene/HGNC:17245#orthology", "database": "AGR" }, { "id": "HGNC:2300", "url": "https://alliancegenome.org/gene/HGNC:2300#orthology", "database": "AGR" }, { "id": "HGNC:2298", "url": "https://alliancegenome.org/gene/HGNC:2298#orthology", "database": "AGR" }, { "id": "HGNC:2296", "url": "https://alliancegenome.org/gene/HGNC:2296#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-1132", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1132#orthology", "database": "AGR" }, { "id": "RGD:2390", "url": "https://alliancegenome.org/gene/RGD:2390#orthology", "database": "AGR" }, { "id": "RGD:71035", "url": "https://alliancegenome.org/gene/RGD:71035#orthology", "database": "AGR" }, { "id": "RGD:1311764", "url": "https://alliancegenome.org/gene/RGD:1311764#orthology", "database": "AGR" }, { "id": "RGD:2388", "url": "https://alliancegenome.org/gene/RGD:2388#orthology", "database": "AGR" }, { "id": "RGD:2391", "url": "https://alliancegenome.org/gene/RGD:2391#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VS67-1", "protein_name": "Peptidase M14 domain-containing protein", "gene_name": "carboxypeptidase b1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTVVWVILALSCLSLSAGLQRTNKYEGYKIYEVSSEARSVAFSEALSELVKNASYYEVFSELNAGNPGKIMVHPHEQVNFVQLMEENNVKYDIINRNVGLTLSRQFETNRMLRHWFPYNGRLGTERYYNHEEINQFIEDLAGEHPRRVFLKTVGRSYEGRWLKTITITNGDARRNKNVILVDGGFHAREWISPAAATYLINQLVYNLEDNADLLLDFDWVILPVVNPDGYEYTQLSEDTRMWRKTRKPSSSDCIGTDPNRNFDFHWNEEGASDDPCDNIYAGAKPFSEPEALVVGDLIHSYVDRGQMYLTLHSYGSLILYPWGWTAAVPDTEEDLHEVAAAGQSAIQEATGTIYKIGPSATTINYAASGASDDYAFNAGFPISFTMELPFGGTGFDPPASDIDSIVKETWVGIAAMARKVIQKYPLA", "length": 427 }, "evidence": [ { "id": "MGI:3045348", "url": "https://alliancegenome.org/gene/MGI:3045348#orthology", "database": "AGR" }, { "id": "MGI:1891837", "url": "https://alliancegenome.org/gene/MGI:1891837#orthology", "database": "AGR" }, { "id": "MGI:88478", "url": "https://alliancegenome.org/gene/MGI:88478#orthology", "database": "AGR" }, { "id": "MGI:1921899", "url": "https://alliancegenome.org/gene/MGI:1921899#orthology", "database": "AGR" }, { "id": "MGI:88479", "url": "https://alliancegenome.org/gene/MGI:88479#orthology", "database": "AGR" }, { "id": "HGNC:15722", "url": "https://alliancegenome.org/gene/HGNC:15722#orthology", "database": "AGR" }, { "id": "HGNC:2299", "url": "https://alliancegenome.org/gene/HGNC:2299#orthology", "database": "AGR" }, { "id": "HGNC:17245", "url": "https://alliancegenome.org/gene/HGNC:17245#orthology", "database": "AGR" }, { "id": "HGNC:2300", "url": "https://alliancegenome.org/gene/HGNC:2300#orthology", "database": "AGR" }, { "id": "HGNC:2298", "url": "https://alliancegenome.org/gene/HGNC:2298#orthology", "database": "AGR" }, { "id": "HGNC:2296", "url": "https://alliancegenome.org/gene/HGNC:2296#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070619-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070619-6#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-1132", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1132#orthology", "database": "AGR" }, { "id": "RGD:2390", "url": "https://alliancegenome.org/gene/RGD:2390#orthology", "database": "AGR" }, { "id": "RGD:71035", "url": "https://alliancegenome.org/gene/RGD:71035#orthology", "database": "AGR" }, { "id": "RGD:1311764", "url": "https://alliancegenome.org/gene/RGD:1311764#orthology", "database": "AGR" }, { "id": "RGD:2388", "url": "https://alliancegenome.org/gene/RGD:2388#orthology", "database": "AGR" }, { "id": "RGD:2391", "url": "https://alliancegenome.org/gene/RGD:2391#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W475-1", "protein_name": "Peptidase M14 domain-containing protein", "gene_name": "Dmel\\CG3108", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MYNARSRGSAANEGISPKRIVTIGSLLLVLGLNQVASMSLDRLALERNELPADQQQQQQQDVLVDNMKLTSIPSADSSDMYMLVPDTVASQLEDTEHVNRNSIEADPESDPSGSSSSDMLMLESDSSPAMQLVELPSDITVAESQPETEHDTENDQQQPESIEEHVVLMKPASQEAQLEQTVDLATEAAPVPLNDELPEDEESPAATESAVEELEKESEAAMDDQVPEESEIQPEQVQPGEYQSESDGEQAETKPEIEAQPEVEAQPEAEAQPEAEPQLEVEPQPEVESQPEVESQPEVEAQPEVEPQSEVESQPEAESHSEPETQAEVEAQPEVESLPEAESQPEAESQPEREPEVEAEKISDNEVDTTEASLMETLVEGIEDGLTAAMDNLVPEELAEASDKQETELESEDQQSPVTEAIEEQAVPEIEQEKEKEPEQITLADETEQDSAQPSNEEPVEIAPEQHTEAEIAPAKIPEEGKPEEEVQVEEESKPVEESKPEEEIKQQEDAKPEEDDQNYAETQPAVTEVKPEETPADIPVEIPAEVPAEIPAEIPAEVPAEIPAESPAEIAAEVPAEIPAEIPAEIPAETPAETHAEIPADVPAQVVAEAPAETPAETPAEVPAEIPSKVQDEIQSDSTQAEPQVEKEAQQPEKETKPLESSLLTTIIPMVMPQPQVPSQPLQVQDSVLNYVNASFMQQQPSETDLPKTEEESPFNAHLRRYDGAQVWRIVVQTDKDKRMADELQSKYDGQLWKEVKQEVDYLLKPQVLAAAERHIRAANLSRIVLIDNLQRVIEKENPPAEKIAELQNRKGHRLTWQAYHRLEDIHGFIDYMAKTYPDICSTEIIGYSVEKRPLKILKISNGNARNPGIWIDGGMHAREWISPATVTYIANQLVEGWEDLPEHMRSINWYIHPVANPDGYEYSHTTDRLWRKNMRAHGRQCPGVDLNRNFGYKWGGKGTSASPCSQTYRGSKAFSEPETFYISKFISGFPRETFQAYLSFHSYGQYILYPWGYDYQLTQDRADLDRVARQAGTSITKSTGVKYTVGSSATTLYPAAGGSDDWAKGIAGIKYAYTIEMGDTGRYGFVLPARFIQYNGKDGVTFADTVARAIAQGRGKSVARNSSGSRRRGH", "length": 1132 }, "evidence": [ { "id": "MGI:3045348", "url": "https://alliancegenome.org/gene/MGI:3045348#orthology", "database": "AGR" }, { "id": "MGI:1891837", "url": "https://alliancegenome.org/gene/MGI:1891837#orthology", "database": "AGR" }, { "id": "MGI:88478", "url": "https://alliancegenome.org/gene/MGI:88478#orthology", "database": "AGR" }, { "id": "MGI:1921899", "url": "https://alliancegenome.org/gene/MGI:1921899#orthology", "database": "AGR" }, { "id": "MGI:88479", "url": "https://alliancegenome.org/gene/MGI:88479#orthology", "database": "AGR" }, { "id": "HGNC:2300", "url": "https://alliancegenome.org/gene/HGNC:2300#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070619-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070619-6#orthology", "database": "AGR" }, { "id": "RGD:2390", "url": "https://alliancegenome.org/gene/RGD:2390#orthology", "database": "AGR" }, { "id": "RGD:71035", "url": "https://alliancegenome.org/gene/RGD:71035#orthology", "database": "AGR" }, { "id": "RGD:1311764", "url": "https://alliancegenome.org/gene/RGD:1311764#orthology", "database": "AGR" }, { "id": "RGD:2388", "url": "https://alliancegenome.org/gene/RGD:2388#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W477-1", "protein_name": "Peptidase M14 domain-containing protein", "gene_name": "CG15768", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MHRLPWKWAWLPLLLLITAKLEQVGGKTYLDWARTDSQLTRLPFFGGGVGHLLRYLHPLSMSPPSERGKISELRSELDANYVSYRGAQLWKLNFNATRGSSMAEREEDDEAAEKRQVLASPDAQFNEVVALFALTFVALIGSVFGQKLLLWRSVSVPEISGISGLPLALLTLNSSELYESTLEGLQWLSPMDLRRFDFISPGSSYQINRRYRNGSQVQRYYGFQLWKVHETRLEQPELRAFWRHFGSEVWNINQDGIDILIEQRNVADARKFMDKVGYSYNIMIDDIESAIDESYVEVPAVEHPLDSVRNNSLPWMEVPGSTMNWRRYHDQADIKQFLQTLLETYSENVELIQIGVTRNKRPLEVIRVSNGNPDNWAVFVDAGLQARDWLSPAALTYAISKLTHLWGRPKGKDKGEGQRQSRAEKAMRRIDWYFLPLANPDGYQYSRQTDRLWTKNRGYDSVSGCYGVNLDRNFDYGWDGTGSTSNPCKNLYRGAHSFSEPESRAVCSFLSGMREYLGAYVSLGGYGQAITYPWGDADYVTENQRNLKQTARRAVLALRRLNQAEYSSGTSYRQKLARPGNSADWVQDRIGPQLVFNMFLKDQGRYGYLLPPHYIVESGEEVFEFLRIIAQQLQ", "length": 634 }, "evidence": [ { "id": "MGI:3045348", "url": "https://alliancegenome.org/gene/MGI:3045348#orthology", "database": "AGR" }, { "id": "MGI:1891837", "url": "https://alliancegenome.org/gene/MGI:1891837#orthology", "database": "AGR" }, { "id": "MGI:88478", "url": "https://alliancegenome.org/gene/MGI:88478#orthology", "database": "AGR" }, { "id": "MGI:1921899", "url": "https://alliancegenome.org/gene/MGI:1921899#orthology", "database": "AGR" }, { "id": "MGI:88479", "url": "https://alliancegenome.org/gene/MGI:88479#orthology", "database": "AGR" }, { "id": "HGNC:15722", "url": "https://alliancegenome.org/gene/HGNC:15722#orthology", "database": "AGR" }, { "id": "HGNC:2299", "url": "https://alliancegenome.org/gene/HGNC:2299#orthology", "database": "AGR" }, { "id": "HGNC:17245", "url": "https://alliancegenome.org/gene/HGNC:17245#orthology", "database": "AGR" }, { "id": "HGNC:21011", "url": "https://alliancegenome.org/gene/HGNC:21011#orthology", "database": "AGR" }, { "id": "HGNC:2300", "url": "https://alliancegenome.org/gene/HGNC:2300#orthology", "database": "AGR" }, { "id": "HGNC:2298", "url": "https://alliancegenome.org/gene/HGNC:2298#orthology", "database": "AGR" }, { "id": "HGNC:2296", "url": "https://alliancegenome.org/gene/HGNC:2296#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070619-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070619-6#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-1132", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1132#orthology", "database": "AGR" }, { "id": "RGD:2390", "url": "https://alliancegenome.org/gene/RGD:2390#orthology", "database": "AGR" }, { "id": "RGD:71035", "url": "https://alliancegenome.org/gene/RGD:71035#orthology", "database": "AGR" }, { "id": "RGD:1311764", "url": "https://alliancegenome.org/gene/RGD:1311764#orthology", "database": "AGR" }, { "id": "RGD:2388", "url": "https://alliancegenome.org/gene/RGD:2388#orthology", "database": "AGR" }, { "id": "RGD:2391", "url": "https://alliancegenome.org/gene/RGD:2391#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W478-1", "protein_name": "Peptidase M14 domain-containing protein", "gene_name": "Dmel\\CG3097", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTQKTMLLQLLLLVAAVAASLANELPSNLTLLDANEIPQRYDEAQLWRIYNISEAMQKRVPVGQMLEQKFGGNIWKENSKFLDISIARDQLKAARSFLSAHRLDPQILSHNIQSMIDEELLEGIQSSSFGHGRRTKKAARSSMHWKDYHDLETIYSFMREIRTKFPNIVRLYTIGQTAEGRDLKVLRISENPRENKKVWIDGGIHAREWISPATVTFILYQLMSDWENQPAHIRGLTWYIMPVMNPDGYEYSRTTNRLWRKNRSPSRRAQCSGVDLNRNFDIGWNGYGSSTNPCSDTYRGSAPASERETRAVAEFLAKRKYNLESYLTFHSYGQMIVYPWAYKAVKVKDASVLQRVSSLAAERILQKTGTSYRAAVTHEVLGIAGGGSDDWSRAALGVKYVYTIELRDRGAYGFVLPPRFIKDTALEGWTVVETVAQAIGPSSSG", "length": 445 }, "evidence": [ { "id": "MGI:3045348", "url": "https://alliancegenome.org/gene/MGI:3045348#orthology", "database": "AGR" }, { "id": "MGI:1891837", "url": "https://alliancegenome.org/gene/MGI:1891837#orthology", "database": "AGR" }, { "id": "MGI:88478", "url": "https://alliancegenome.org/gene/MGI:88478#orthology", "database": "AGR" }, { "id": "MGI:1921899", "url": "https://alliancegenome.org/gene/MGI:1921899#orthology", "database": "AGR" }, { "id": "MGI:88479", "url": "https://alliancegenome.org/gene/MGI:88479#orthology", "database": "AGR" }, { "id": "HGNC:17245", "url": "https://alliancegenome.org/gene/HGNC:17245#orthology", "database": "AGR" }, { "id": "HGNC:2298", "url": "https://alliancegenome.org/gene/HGNC:2298#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070619-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070619-6#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-1132", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1132#orthology", "database": "AGR" }, { "id": "RGD:2390", "url": "https://alliancegenome.org/gene/RGD:2390#orthology", "database": "AGR" }, { "id": "RGD:71035", "url": "https://alliancegenome.org/gene/RGD:71035#orthology", "database": "AGR" }, { "id": "RGD:1311764", "url": "https://alliancegenome.org/gene/RGD:1311764#orthology", "database": "AGR" }, { "id": "RGD:2388", "url": "https://alliancegenome.org/gene/RGD:2388#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VS80", "url": "https://www.uniprot.org/uniprotkb/Q9VS80" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9VS80", "url": "https://www.uniprot.org/uniprotkb/Q9VS80" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9VS80", "url": "https://www.uniprot.org/uniprotkb/Q9VS80" } ], "pmid": "" }, { "name": "metallocarboxypeptidase activity", "id": "GO:0004181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004181", "evidence": [ { "database": "UniProtKB", "id": "Q9VS80", "url": "https://www.uniprot.org/uniprotkb/Q9VS80" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 227, "end_pos": 229, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VS80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VS80" }, { "id": "PS52035", "database": "PROSITE", "url": "https://prosite.expasy.org/PS52035" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase M14", "eco_id": "ECO_0000259", "start_pos": 37, "end_pos": 336, "start_aa": "Asn", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 227, "end_pos": 229 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VSA9-1", "uniprot_ac": "Q9VSA9", "uniprot_id": "Q9VSA9_DROME", "mass": { "chemical_mass": 17966.0, "monoisotopic_mass": 17966.0 }, "refseq": { "ac": "NP_648155", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648155" }, "gene_names": [ { "name": "Dmel\\CG7409", "type": "recommended", "evidence": [ { "id": "Q9VSA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSA9" } ] }, { "name": "CG7409", "type": "synonym", "evidence": [ { "id": "NP_648155", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648155" }, { "id": "Q9VSA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSA9" } ] }, { "name": "CT16169", "type": "synonym", "evidence": [ { "id": "NP_648155", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648155" }, { "id": "Q9VSA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSA9" } ] }, { "name": "Dmel46.9", "type": "synonym", "evidence": [ { "id": "NP_648155", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648155" }, { "id": "Q9VSA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSA9" } ] }, { "name": "Dmel\\CG7409", "type": "synonym", "evidence": [ { "id": "NP_648155", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648155" } ] }, { "name": "Dmel_CG7409", "type": "synonym", "evidence": [ { "id": "Q9VSA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSA9" } ] } ], "protein_names": [ { "name": "SHSP domain-containing protein", "type": "recommended", "evidence": [ { "id": "Q9VSA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSA9/entry#names_and_taxonomy" } ] }, { "name": "CG7409-PA", "type": "synonym", "evidence": [ { "id": "NP_648155", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648155" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_648155", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648155" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VSA9", "url": "https://www.uniprot.org/uniprotkb/Q9VSA9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG7409", "url": "https://www.uniprot.org/uniprotkb/Q9VSA9", "locus": { "chromosome": "3L", "start_pos": 7755168, "end_pos": 7754409, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0035817", "url": "https://www.ensemblgenomes.org/id/FBgn0035817" } ] } } ], "crossref": [ { "id": "FB:FBgn0035817", "url": "https://alliancegenome.org/gene/FB:FBgn0035817", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0035817", "url": "https://bgee.org/?page=gene&gene_id=FBgn0035817", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06526", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06526", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0035817", "url": "https://flybase.org/reports/FBgn0035817", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "38870", "url": "https://www.ncbi.nlm.nih.gov/gene/38870", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VSA9", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VSA9*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR001436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002068", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002068", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008978", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008978", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG7409", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG7409", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DWDLADW", "url": "https://omabrowser.org/oma/group/DWDLADW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VSA9", "url": "https://www.orthodb.org/?gene=Q9VSA9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45640", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45640", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45640:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45640:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00011", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00011", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-3371571", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-3371571", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_648155", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648155", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VSA9", "url": "https://www.uniprot.org/uniprotkb/Q9VSA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VSA9-1", "url": "https://www.uniprot.org/uniprotkb/Q9VSA9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALVPATNNTDWDYWDYRRRLWRDWDLNDWDLPYWKRSLSRVGSAPDLSRVIVGKDGFEANVDVHLFKPYEISVKTSGDTVVVEAKHEKRRDGDTFVGRHIVKRFVLPRGYYPNDVRSELSSDGILTVKCPPYLTNERSVYVRQVGPSYLSIKN", "length": 154, "header": "tr|Q9VSA9-1|Q9VSA9_DROME Isoform 1 of SHSP domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG7409 PE=3 SV=1 CANONICAL=Q9VSA9-1" }, "isoforms": [ { "isoform_ac": "Q9VSA9-1", "url": "https://www.uniprot.org/uniprotkb/Q9VSA9/entry#Q9VSA9-1", "sequence": { "sequence": "MALVPATNNTDWDYWDYRRRLWRDWDLNDWDLPYWKRSLSRVGSAPDLSRVIVGKDGFEANVDVHLFKPYEISVKTSGDTVVVEAKHEKRRDGDTFVGRHIVKRFVLPRGYYPNDVRSELSSDGILTVKCPPYLTNERSVYVRQVGPSYLSIKN", "length": 154, "header": "tr|Q9VSA9-1|Q9VSA9_DROME Isoform 1 of SHSP domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG7409 PE=3 SV=1 CANONICAL=Q9VSA9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], 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"UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VSD3-1", "url": "https://www.uniprot.org/uniprotkb/Q9VSD3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSDNTESKLALDPCDVIVFEGPFNRSVSRKLVIKNTSKTQRMAFKMKTTTPKLFYVRPNIGVLGPEQKVSVDIFMQPILQEQIKKRHKFLLLAAEVTGDISDVQEFWKMQNPNETRETKIKCELVPSKEDDFRQAGGSAVISTDNKDGEVHFDAQEVSEPMAKLLKQVSMLEDEHMALTDQIDGLRDQAIGRTFFYMAAIVIIILSAVAGAYYGKTRL", "length": 218, "header": "tr|Q9VSD3-1|Q9VSD3_DROME Isoform 1 of Farinelli OS=Drosophila melanogaster OX=7227 GN=fan PE=3 SV=3 CANONICAL=Q9VSD3-1" }, "isoforms": [ { "isoform_ac": "Q9VSD3-1", "url": "https://www.uniprot.org/uniprotkb/Q9VSD3/entry#Q9VSD3-1", "sequence": { "sequence": "MSDNTESKLALDPCDVIVFEGPFNRSVSRKLVIKNTSKTQRMAFKMKTTTPKLFYVRPNIGVLGPEQKVSVDIFMQPILQEQIKKRHKFLLLAAEVTGDISDVQEFWKMQNPNETRETKIKCELVPSKEDDFRQAGGSAVISTDNKDGEVHFDAQEVSEPMAKLLKQVSMLEDEHMALTDQIDGLRDQAIGRTFFYMAAIVIIILSAVAGAYYGKTRL", "length": 218, "header": "tr|Q9VSD3-1|Q9VSD3_DROME Isoform 1 of 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Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VSD3", "url": "https://www.uniprot.org/uniprotkb/Q9VSD3" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VSD3", "url": "https://www.uniprot.org/uniprotkb/Q9VSD3" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VSD3", "url": "https://www.uniprot.org/uniprotkb/Q9VSD3" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VSD3", "url": "https://www.uniprot.org/uniprotkb/Q9VSD3" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VSD3", "url": "https://www.uniprot.org/uniprotkb/Q9VSD3" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VSD3", "url": "https://www.uniprot.org/uniprotkb/Q9VSD3" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VSD3", "url": "https://www.uniprot.org/uniprotkb/Q9VSD3" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VSD3", "url": "https://www.uniprot.org/uniprotkb/Q9VSD3" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VSD3", "url": "https://www.uniprot.org/uniprotkb/Q9VSD3" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSD6" } ] }, { "name": "Dim7", "type": "synonym", "evidence": [ { "id": "NP_524780", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524780" }, { "id": "Q9VSD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSD6" } ] }, { "name": "DmRanBP7", "type": "synonym", "evidence": [ { "id": "NP_524780", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524780" }, { "id": "Q9VSD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSD6" } ] }, { "name": "Dmel\\CG7935", "type": "synonym", "evidence": [ { "id": "NP_524780", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524780" }, { "id": "Q9VSD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSD6" } ] }, { "name": "Dmel_CG7935", "type": "synonym", "evidence": [ { "id": "Q9VSD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSD6" } ] }, { "name": "Imp 7", "type": "synonym", "evidence": [ { "id": "NP_524780", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524780" }, { "id": "Q9VSD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSD6" } ] }, { "name": "Imp7/8", "type": "synonym", "evidence": [ { "id": "NP_524780", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524780" } ] }, { "name": "Imp7", "type": "synonym", "evidence": [ { "id": "NP_524780", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524780" }, { "id": "Q9VSD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSD6" } ] }, { "name": "Msk", "type": "synonym", "evidence": [ { "id": "NP_524780", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524780" }, { "id": "Q9VSD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSD6" } ] }, { "name": "S(ls)2", "type": "synonym", "evidence": [ { "id": "NP_524780", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524780" }, { "id": "Q9VSD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSD6" } ] }, { "name": "dim-7", "type": "synonym", "evidence": [ { "id": "NP_524780", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524780" }, { "id": "Q9VSD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSD6" } ] }, { "name": "dim7", "type": "synonym", "evidence": [ { "id": "NP_524780", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524780" }, { "id": "Q9VSD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSD6" } ] }, { "name": "msk", "type": "synonym", "evidence": [ { "id": "NP_524780", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524780" } ] } ], "protein_names": [ { "name": "CG7935-PA", "type": "synonym", "evidence": [ { "id": "NP_524780", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524780" } ] }, { "name": "Importin-7", "type": "synonym", "evidence": [ { "id": "NP_524780", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524780" } ] }, { "name": "Moleskin", "type": "synonym", "evidence": [ { "id": "Q9VSD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSD6/entry#names_and_taxonomy" } ] }, { "name": "corkscrew interacting Protein-61", "type": "synonym", "evidence": [ { "id": "NP_524780", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524780" } ] }, { "name": "diminished-7", "type": "synonym", "evidence": [ { "id": "NP_524780", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524780" } ] }, { "name": "drosophila Importin-7", "type": "synonym", "evidence": [ { "id": "NP_524780", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524780" } ] }, { "name": "moleskin", "type": "synonym", "evidence": [ { "id": "NP_524780", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524780" } ] }, { "name": "msk-PA", "type": "synonym", "evidence": [ { "id": "NP_524780", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524780" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VSD6", "url": "https://www.uniprot.org/uniprotkb/Q9VSD6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "msk", "url": "https://www.uniprot.org/uniprotkb/Q9VSD6", "locus": { "chromosome": "3L", "start_pos": 8121579, "end_pos": 8116179, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0026252", "url": "https://www.ensemblgenomes.org/id/FBgn0026252" } ] } } ], "crossref": [ { "id": "FB:FBgn0026252", "url": "https://alliancegenome.org/gene/FB:FBgn0026252", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0026252", "url": "https://bgee.org/?page=gene&gene_id=FBgn0026252", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0026252", "url": "https://flybase.org/reports/FBgn0026252", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "44747", "url": "https://www.ncbi.nlm.nih.gov/gene/44747", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VSD6", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VSD6*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR001494", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001494", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013713", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013713", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058669", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058669", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG7935", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG7935", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WVAKTSW", "url": "https://omabrowser.org/oma/group/WVAKTSW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VSD6", "url": "https://www.orthodb.org/?gene=Q9VSD6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10997", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10997", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10997:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10997:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03810", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03810", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08506", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08506", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25758", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25758", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-5578749", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-5578749", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_524780", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524780", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VSD6", "url": "https://www.uniprot.org/uniprotkb/Q9VSD6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VSD6-1", "url": "https://www.uniprot.org/uniprotkb/Q9VSD6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAQKLTELLRATIDPNPEQRKAAEDQLAQIHKIIGFVPTILQIVMQTTVEQPVRQAGAVYLKNLINSSWSDHEAKPGEPIPFSIHEQDRAMIRGAIVDAIVHAPELIRVQLSVCVNHIIKSDFPGRWPQVVDSISIYLQNQDVNGWNGALVTMYQLVKTYEYKRHEERTPLNEAMNLLLPMIYQLMVRLLAEQSEQSVLLQKQILKIYYALTQYTLPLDLITKEIFSQWMEICRQVADRAVPDSSHLDDDERTEFPYWKTKKWALHIMVRMFERYGSPSNVVSEKYQKFAEWYLPTFSQGVLEVLLKILDQYRNRVYVSPRVLTDVLNYLKNAVSHAYTWKLIKPHMVAVIQDVIFPIMSFTDSDQELWESDPYEYIRLKFDIFEDYATPVPAAQSLLHSMCKKRKGILPKAMATIMQIITSPNADNKQKDGALHMIGTLADVLLKKASYRDQVESMLTTYVFPEFQNPAGHMRARACWVLHYFCDVQIKNPQVLAEIMRLTTNALLTDKELPVKVEAAIGLQMFISSQDEAPQYVEAQIKEITKELLTIIRETENEDLTNVMQKIVCTFTEQLLPVATEICQHLATTFSQVLESEEGSDEKAITAMSLLNTIETLLSVMEEHPDVLLNLHPIVINVVGHIFQHNITDFYEETFSLVYDLTAKAISPEMWQMLELIYQVFKKDGIDYFIDIMPALHNYVTVDTPAFLSNPNRLLAILDMCKTMLTSSPGEDPECHAAKLMEVIILQCKGQIDSVIHMFVELALSRLTREVQSSELRTMCLQVVIAALYYNPQLLLSILDKMSQQNNDSISAHFIKQWLHDTDCFLGIHDRKLCVLGLCTLISLGEAKPQVLSEVAGKIVPALILLFDGLKRAYESRAQEEEEDEEEEDGDDCEEALSSDEDDMDEMAPDYLDKLAEFAKTKGNESGFEVKAEIKDDDADSDGDAEESVGDLNETGLESFTTPIDDEENESAIDEYWTFKEVITALSAQDQAWYALLTSNLTPEQAKALQEVVVTADQRKAAKESKLIEKQGGFAFPQTAVPTSFKFGS", "length": 1049, "header": "tr|Q9VSD6-1|Q9VSD6_DROME Isoform 1 of Moleskin OS=Drosophila melanogaster OX=7227 GN=msk PE=1 SV=1 CANONICAL=Q9VSD6-1" }, "isoforms": [ { "isoform_ac": "Q9VSD6-1", "url": "https://www.uniprot.org/uniprotkb/Q9VSD6/entry#Q9VSD6-1", "sequence": { "sequence": "MEAQKLTELLRATIDPNPEQRKAAEDQLAQIHKIIGFVPTILQIVMQTTVEQPVRQAGAVYLKNLINSSWSDHEAKPGEPIPFSIHEQDRAMIRGAIVDAIVHAPELIRVQLSVCVNHIIKSDFPGRWPQVVDSISIYLQNQDVNGWNGALVTMYQLVKTYEYKRHEERTPLNEAMNLLLPMIYQLMVRLLAEQSEQSVLLQKQILKIYYALTQYTLPLDLITKEIFSQWMEICRQVADRAVPDSSHLDDDERTEFPYWKTKKWALHIMVRMFERYGSPSNVVSEKYQKFAEWYLPTFSQGVLEVLLKILDQYRNRVYVSPRVLTDVLNYLKNAVSHAYTWKLIKPHMVAVIQDVIFPIMSFTDSDQELWESDPYEYIRLKFDIFEDYATPVPAAQSLLHSMCKKRKGILPKAMATIMQIITSPNADNKQKDGALHMIGTLADVLLKKASYRDQVESMLTTYVFPEFQNPAGHMRARACWVLHYFCDVQIKNPQVLAEIMRLTTNALLTDKELPVKVEAAIGLQMFISSQDEAPQYVEAQIKEITKELLTIIRETENEDLTNVMQKIVCTFTEQLLPVATEICQHLATTFSQVLESEEGSDEKAITAMSLLNTIETLLSVMEEHPDVLLNLHPIVINVVGHIFQHNITDFYEETFSLVYDLTAKAISPEMWQMLELIYQVFKKDGIDYFIDIMPALHNYVTVDTPAFLSNPNRLLAILDMCKTMLTSSPGEDPECHAAKLMEVIILQCKGQIDSVIHMFVELALSRLTREVQSSELRTMCLQVVIAALYYNPQLLLSILDKMSQQNNDSISAHFIKQWLHDTDCFLGIHDRKLCVLGLCTLISLGEAKPQVLSEVAGKIVPALILLFDGLKRAYESRAQEEEEDEEEEDGDDCEEALSSDEDDMDEMAPDYLDKLAEFAKTKGNESGFEVKAEIKDDDADSDGDAEESVGDLNETGLESFTTPIDDEENESAIDEYWTFKEVITALSAQDQAWYALLTSNLTPEQAKALQEVVVTADQRKAAKESKLIEKQGGFAFPQTAVPTSFKFGS", "length": 1049, "header": "tr|Q9VSD6-1|Q9VSD6_DROME Isoform 1 of Moleskin OS=Drosophila melanogaster OX=7227 GN=msk PE=1 SV=1 CANONICAL=Q9VSD6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VSD6", "url": "https://www.uniprot.org/uniprotkb/Q9VSD6" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VSD6", "url": "https://www.uniprot.org/uniprotkb/Q9VSD6" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VSD6", "url": "https://www.uniprot.org/uniprotkb/Q9VSD6" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VSD6", "url": "https://www.uniprot.org/uniprotkb/Q9VSD6" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VSD6", "url": "https://www.uniprot.org/uniprotkb/Q9VSD6" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VSD6", "url": "https://www.uniprot.org/uniprotkb/Q9VSD6" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VSD6", "url": "https://www.uniprot.org/uniprotkb/Q9VSD6" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VSD6", "url": "https://www.uniprot.org/uniprotkb/Q9VSD6" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VSD6", "url": "https://www.uniprot.org/uniprotkb/Q9VSD6" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VSD6", "url": "https://www.uniprot.org/uniprotkb/Q9VSD6" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VSD6", "url": "https://www.uniprot.org/uniprotkb/Q9VSD6" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG7935", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG7935", "resource": "KEGG Pathway" }, { "id": "R-DME-5578749", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-5578749", "resource": "Reactome", "description": "Transcriptional regulation by small RNAs" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K6J6-1", "protein_name": "Importin 8", "gene_name": "Ipo8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLNRIIQALKGTIDPKLRIAAETELNQSYKIINFAPSLLRIIVSDHVEFPVRQAAAIYLKNMVTQYWPDREPPPGEVIFPFNIHENDRQQIRDNIVEGIIRSPDLVRVQLTMCLRVIIRHDFPGHWPAVVDKIDYYLKSPNSGNWLGSLLCLYQLVKTYEYKKAEEREPLLAAMQIFLPRIQQQILQLLPDASHYSVLLQKQILKIFYALVQYALPLQLVNHQTMTTWMEIFRTIIDRTVPPETLQIDEDDRPELVWWKCKKWALHIVTRLFERYGSPGNVTKEYFEFSEFFLKTYAVGIQQVLLKILDQYRQKEYIAPRVLQQALNYLNQGVVHAVTWKQMKPHMQNISEDVIFSVMCYKDEDEELWQEDPYEYIRVKFDIFEDYASPTTAAQTLLYTAAKKRKEVLPKMMAFCYQILTDPNFDPRKKDGALHVIGSLAEILLKKSLFKDQIELFLQNHVFPLILSNLGYLRARSCWVLHAFSSLKFHNELNLRNAVELAKKSLIEDLEMPVKVEAALALQSLISNQTQAKEYMKPYVRFIMQELLHIVKETESDDVTNVIQKLICEYSHDMASIAVDITQHLAEIFGKVLQSDEYEEIEDKTVMAMGILHTIDTILTVVEDHPEIIQQLENICLRIIDLVLQKHVIEFYEEILSLAYNLTCHAISPQMWQLLGILFEVFQQDCFEYFTDMMPLLHNYVTVDTNALLSNPKHLEVLFTMCRKVLCGESGEDAECYAAKLLEVIILQCKGRGIDQCIPLFIQLVLERLTRGVKTSELRTMCLQVAIAALYYSPELLFHTLERVQLPHNPGPVTSQFINQWMSDTDYFLGHHDRKMCIIGLSVLLELQNRPPAVDAVAAQILPSILFLFLGLKQVCATRQTVNRENHSKAEKADIEENEEISSEEEEETSVNAQAMQSQICRGEEEEDDDWDEEVVEETALEGFSTPLDLDNSVDEYQFFTQALLTVQNRDAAWYQLLVAPLSEDQKRKLQEVYTLAEHRRTLAGQFHI", "length": 1009 }, "evidence": [ { "id": "MGI:2444611", "url": "https://alliancegenome.org/gene/MGI:2444611#orthology", "database": "AGR" }, { "id": "HGNC:9853", "url": "https://alliancegenome.org/gene/HGNC:9853#orthology", "database": "AGR" }, { "id": "FB:FBgn0026252", "url": "https://alliancegenome.org/gene/FB:FBgn0026252#orthology", "database": "AGR" }, { "id": "RGD:1593688", "url": "https://alliancegenome.org/gene/RGD:1593688#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-3#orthology", "database": "AGR" }, { "id": "SGD:S000003893", "url": "https://alliancegenome.org/gene/SGD:S000003893#orthology", "database": "AGR" }, { "id": "SGD:S000002803", "url": "https://alliancegenome.org/gene/SGD:S000002803#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A2R8RMT5-1", "protein_name": "Importin-8 isoform X1", "gene_name": "ipo8", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDPNRIIQALKGTIDPNLRLAAENELNQSYKIINFAPTLLQIIVSEQVEFPVRQAAAIYLKNMVSQYWQDREPTLGEVVFPFNIHENDRGQIRENMVEAIIRCPESIRAQLTVCLRAIIKHDFPGRWTGVVDKINLYLQSQNSGSWYGSLLALYQLVKNYEFKKAEERDPLLAAMQIFLPRLQQLITQLLSDATFISVLIQKQILKIFHALVQYSFPLQLINNTVMTHWMEILRTVVDRDVPAETLEADEDDRPELIWWKCKKWALHILTRIFERYGSPGNVTKEYVEFADFFLKTYALGIQQVLLKVMEQHRQRQYVSPRVLQQTLSFMTQGVSHSLTWRQMKPHMQTITHELVFPLMCYKDEDERLWQEDPYEYIRMKFNVYDDHVSPATAAQTLLCTAARKRKEVLPQMMEFCHQILVDPSADPRRTDGALHVIGTLAQPLLKKRVYRDQMELMLQNYVFPLLNSNLAYLRARSCWVLHSFSPLKFHNELVLRNAVELVKHNLVEDKEMPVKVEAAIALQTLVRNQEQAKVYIRPFIRPVMQELLHIIKETENDDLTGVIQKMICEYSEEVTVIAVDMTQNLAEIFSKILQSEEYEESEDKTVMALGILSTIDTILTVMGDRKEISQQLEGICLQVIGLVLQKPIIGMAEFYEEILSLAFGLTCYCISPQMWQLLGVLYDVFQHDCFDYFTDMMPLLHNYVTVDTNMLLSDPKYLEVIYTMCKKVLTSDAGEDPECHAAKLLEVIILQCRGRGIDQCIPLFVEAVLERLTRGVKSSELRTMCLQVVIAALYYNPTLLIHTLENIRFPHSPEPITAQFINQWMNDTEFFLGLHDRKMCVIGLSILMELPSRPAVLEEVVGQIVPSVLLLFLGLKHIYASRVLNKPEQFGRAQGSEEEENEEIPSDEDEVGEKGVALQPSVAPTGNDNEDDDDEDDDEYWDDEGLEGTPLEEYSTPLDCDNGEDEYQFFTASLLRVQSSDAGWYQSLTSPLNEDQRKQLQEIYNLAQQRRSTGVKGL", "length": 1018 }, "evidence": [ { "id": "MGI:2444611", "url": "https://alliancegenome.org/gene/MGI:2444611#orthology", "database": "AGR" }, { "id": "HGNC:9853", "url": "https://alliancegenome.org/gene/HGNC:9853#orthology", "database": "AGR" }, { "id": "FB:FBgn0026252", "url": "https://alliancegenome.org/gene/FB:FBgn0026252#orthology", "database": "AGR" }, { "id": "RGD:1593688", "url": "https://alliancegenome.org/gene/RGD:1593688#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-3#orthology", "database": "AGR" }, { "id": "SGD:S000003893", "url": "https://alliancegenome.org/gene/SGD:S000003893#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0ZGU8-1", "protein_name": "Importin 7", "gene_name": "IPO7", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MDPNTIIEALRGTMDPALREAAERQLNEAHKSVNFVSTLLQITMSEQLDLPVRQAGVIYLKNMITQYWPDRETAPGEIPPYSIPEEDRHCIRENIVEAIIHSPELIRVQLTTCIHHIIKHDYPSRWTAVVEKIGFYLQSDNSACWLGILLCLYQLVKNYEYKKPEERSPLIAAMQHFLPVLKDSFIQLLSDPSDQSVLIQKQIFKIFYALVQYTLPLELINQQNLTEWIEILKTVVDRDVPAETLQVDEDDRPELPWWKCKKWALHILARLFERYGSPGNVSKEYNEFAEVFLKAFAVGVQQVLLKVLYQYKEKQYMAPRVLQQTLNYINQGVSHAVTWKNLKPHIQGIIQDVIFPLMCYTDADEELWQEDPYEYIRMKFDVFEDFISPTTAAQTLLFTSCSKRKEVLQKTMGFCYQILTEPNADPRKKDGALHMIGSLAEILLKKKIYKDQMEYMLQNHVFPLFSSELGYMRARACWVLHYFCEVKFKSDQNLQTALELTRRCLIDDREMPVKVEAAIALQVLISNQEKAKEYITPFIRPVMQALLHIIRETENDDLTNVIQKMICEYSEEVTPIAVEMTQHLAMTFNQVIQTGPDEEGSDDKAVTAMGILNTIDTLLSVVEDHKEITQQLEGICLQVIGTVLQQHVLEFYEEIFSLAHSLTCQQVSAQMWQLLPLVFEVFQQDGFDYFTDMMPLLHNYVTVDTDTLLSDTKYLEMIYSMCKKVLTGVAGEDAECHAAKLLEVIILQCKGRGIDQCIPLFVEAALERLTREVKTSELRTMCLQVAIAALYYNPHLLLNTLENLRFPNNVEPVTNHFITQWLNDVDCFLGLHDRKMCVLGLCALIDLEQIPQVLNQVAGQILPAFILLFNGLKRAYACHAEHENDSDDDDEAEEDEETEELGSDEDDIDEDGQEYLEILAKQAGEDGDDEDWEEDDAEETALEGYSTIIDDEDNPVDEYQIFKTIFQTIQNRNPVWYQTLTQGLNEEQRKQLQDYRKSHLQYKLGGRLNFYTCGGMSICPTSLFSLPYLGVYSFSVNKVIE", "length": 1041 }, "evidence": [ { "id": "Q9VSD6", "url": "https://omabrowser.org/oma/group/Q9VSD6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4AE96-1", "protein_name": "Importin 7", "gene_name": "Ipo7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDPNTIIEALRGTMDPALREAAERQLNEAHKSLNFVSTLLQITMSEQLDLPVRQAGVIYLKNMITQYWPDREATPGDISPYTIPEEDRHCIRENIVEAIIHSPELIRVQLTTCIHHIIKHDYPSRWTAIVDKIGFYLQSDNSACWLGILLCLYQLVKNYEYKKPEERSPLVAAMQHFLPVLKDRFIQLLSDQSDQSVLIQKQIFKIFYALVQYTLPLELINQQNLTEWVEILKTVVNRDVPNETLQVEEDDRPELPWWKCKKWALHILARLFERYGSPGNVSKEYNEFAEVFLKAFAVGVQQVLLKVLYQYKEKQYMAPRVLQQTLNYINQGVSHALTWKNLKPHIQGIIQDVIFPLMCYTDADEELWQEDPYEYIRMKFDVFEDFISPTTAAQTLLFTACSKRKEVLQKTMGFCYQILTEPNADPRKKDGALHMIGSLAEILLKKKIYKDQMEYMLQNHVFPLFSSELGYMRARACWVLHYFCEVKFKSDQNLQTALELTRRCLIDDREMPVKVEAAIALQVLISNQEKAKEYITPFIRPVMQALLHIIRETENDDLTNVIQKMICEYSEEVTPIAVEMTQHLAMTFNQVIQTGPDEEGSDDKAVTAMGILNTIDTLLSVVEDHKEITQQLEGICLQVIGTVLQQHVLEFYEEIFSLAHSLTCQQVSPQMWQLLPLVFEVFQQDGFDYFTDMMPLLHNYVTVDTDTLLSDTKYLEMIYSMCKKVLTGVAGEDAECHAAKLLEVIILQCKGRGIDQCIPLFVEAALERLTREVKTSELRTMCLQVAIAALYYNPHLLLNTLENLRFPNNVEPVTNHFITQWLNDVDCFLGLHDRKMCVLGLCALIDMEQIPQVLNQVSGQILPAFILLFNGLKRAYACHAEHENDSDDDDDAEDDDETEELGSDEDDIDEDGQEYLEILAKQAGEDGDDEDWEEDDAEETALEGYSTIIDDEDNPVDEYQIFKAIFQTIQNRNPVWYQALTHGLNEEQRKQLQDIATLADQRRAAHESKMIEKHGGYKFSAPVVPSSFNFGGPAPGMN", "length": 1038 }, "evidence": [ { "id": "RGD:1310849", "url": "https://alliancegenome.org/gene/RGD:1310849#orthology", "database": "AGR" }, { "id": "MGI:2152414", "url": "https://alliancegenome.org/gene/MGI:2152414#orthology", "database": "AGR" }, { "id": "HGNC:9852", "url": "https://alliancegenome.org/gene/HGNC:9852#orthology", "database": "AGR" }, { "id": "FB:FBgn0026252", "url": "https://alliancegenome.org/gene/FB:FBgn0026252#orthology", "database": "AGR" }, { "id": "SGD:S000003893", "url": "https://alliancegenome.org/gene/SGD:S000003893#orthology", "database": "AGR" }, { "id": "SGD:S000002803", "url": "https://alliancegenome.org/gene/SGD:S000002803#orthology", "database": "AGR" }, { "id": "Q9VSD6", "url": "https://omabrowser.org/oma/group/Q9VSD6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BGE5-1", "protein_name": "Importin 7", "gene_name": "IPO7", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDPNTIIEALRGTMDPALREAAERQLNEAHKSLNFVSTLLQITMSEQLDLPVRQAGVIYLKNMITQYWPDRETAPGDISPYTIPEEDRHCIRENIVEAIIHSPELIRVQLTTCIHHIIKHDYPSRWTAIVDKIGFYLQSDNSACWLGILLCLYQLVKNYEYKKPEERSPLVAAMQHFLPVLKDRFIQLLSDQSDQSVLIQKQIFKIFYALVQYTLPLELINQQNLTEWIEILKTVVNRDVPNETLQVEEDDRPELPWWKCKKWALHILARLFERYGSPGNVSKEYNEFAEVFLKAFAVGVQQVLLKVLYQYKEKQYMAPRVLQQTLNYINQGVSHALTWKNLKPHIQGIIQDVIFPLMCYTDADEELWQEDPYEYIRMKFDVFEDFISPTTAAQTLLFTACSKRKEVLQKTMGFCYQILTEPNADPRKKDGALHMIGSLAEILLKKKIYKDQMEYMLQNHVFPLFSSELGYMRARACWVLHYFCEVKFKSDQNLQTALELTRRCLIDDREMPVKVEAAIALQVLISNQEKAKEYITPFIRPVMQALLHIIRETENDDLTNVIQKMICEYSEEVTPIAVEMTQHLAMTFNQVIQTGPDEEGSDDKAVTAMGILNTIDTLLSVVEDHKEITQQLEGICLQVIGTVLQQHVLEFYEEIFSLAHSLTCQQVSPQMWQLLPLVFEVFQQDGFDYFTDMMPLLHNYVTVDTDTLLSDTKYLEMIYSMCKKVLTGVAGEDAECHAAKLLEVIILQCKGRGIDQCIPLFVEAALERLTREVKTSELRTMCLQVAIAALYYNPHLLLNTLENLRFPNNVEPVTNHFITQWLNDVDCFLGLHDRKMCVLGLCALIDMEQIPQVLNQVSGQILPAFILLFNGLKRAYACHAEHENDSDDDDEAEDDDETEELGSDEDDIDEDGQEYLEILAKQAGEDGDEEDWEEDDAEETALEGYSTIIDDEDNPVDEYQIFKAIFQTIQNRNPVWYQALTHGLNEEQRKQLQDIATLADQRRAAHESKMIEKHGGYKFSAPVVPSSFNFGGPAPGMN", "length": 1038 }, "evidence": [ { "id": "Q9VSD6", "url": "https://omabrowser.org/oma/group/Q9VSD6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F4IRR2-1", "protein_name": "Importin beta-like SAD2", "gene_name": "SAD2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDLHSLALILRTAALSPIPDERKVSEQQLNQLEHTPQHLVRLLQIAVDGNCDMAVRQIASIQFKNLIAKNWSPEDCGPAVRQQQIFESDKELVRDNILVYVTQVPTLLRSQLGESLKTIIYADYPEQWPRLLDWVKYNLQNQQIYGALFVLRILSRKYEFKSDEERTPVSRIVEETFPQLLTIFNGLIQIPNPSLEIAELMKLICKIFWSSIYLELPRQLFDLNVFNAWMVLFLSVSERPVPVEGQPMDPELRKSWGWWKVKKWTVHILNRLYSRFGDPKLQSPENKPFAQMFQKNYAGRILEGHLNFLNTIRVGGYLPDRVINLLLQYLSNSISKNSMYKLLLPRLDVLLFEIVFPLMCFNDNDQKLWEEDPHEYVRKGYNIIEDLYSPRTASMDFVNELVRKRGKENLPKFVKFVVEIFLSYEKATVEEKPYRQKDGAMLAVGALCDKLKQTDPYKSQLELMLVQHIFPDFNSPVGHLRAKAAWVAGQYAHINFSDQNNFRKALHSVVSGLRDPDLPVRVDSVFALRSFVEACKDLNEIRPILPQLLDEFFKLMNEVENEDLVFTLETIVDKFGEEMAPFAFGLCQNLAAAFWRCLNTSEANDDSDDMGALAAVGCLRAISTILESVSSLPQLFVEIEPTILPIMQKMLTTDGQEVFEEVLEIASYMTFYSPSISLDIWSLWPLMVEALVDWGIDFFPNILVPMDNFISRGTAHFLTCKEPDYQQSLYNVLSTLMTDRNIEDSEIESAPKLIEVVFQNCKGQVDQWVEPYLRLTVDRLQRAETSYVKSLLIQVVANMLYYNPGLTLGVLHNTGLASKVFDLWFQMLQQKRKSGLPANFKREHDKKVCCLGLTSLLALPGGQFPDEALQRVFRATLDLLVAYKNQLAEAAKETEVDYEEEMNGLQSSDDDYDDDGSDGEMDDTEEGDEAQSVKLQKLAAQAKAFHYDDDDDDDSDDDFSDEDEFQSPIDEVDAFVFFVDAIRVMQASDAQRFQNLNQSLDFTYQAIANGIAQHAELRRVEIEKEKQKKLAAASTPVTAL", "length": 1040 }, "evidence": [ { "id": "Q9VSD6", "url": "https://omabrowser.org/oma/group/Q9VSD6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "G3I7Z8-1", "protein_name": "Importin-7 isoform X1", "gene_name": "Ipo7", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDPNTIIEALRGTMDPALREAAERQLNEAHKSLNFVSTLLQITMSEQLDLPVRQAGVIYLKNMITQYWPDREATPGDISPYTIPEEDRHCIRENIVEAIIHSPELIRVQLTTCIHHIIKHDYPSRWTAIVDKIGFYLQSDNSACWLGILLCLYQLVKNYEYKKPEERSPLVAAMQHFLPVLKDRFIQLLSDQSDQSVLIQKQIFKIFYALVQYTLPLELINQQNLTEWVEILKTVVNRDVPNETLQVEEDDRPELPWWKCKKWALHILARLFERYGSPGNVSKEYNEFAEVFLKAFAVGVQQVLLKVLYQYKEKQYMAPRVLQQTLNYINQGVSHALTWKNLKPHIQGIIQDVIFPLMCYTDADEELWQEDPYEYIRMKFDVFEDFISPTTAAQTLLFTACSKRKEVLQKTMGFCYQILTEPNADPRKKDGALHMIGSLAEILLKKKIYKDQMEYMLQNHVFPLFSSELGYMRARACWVLHYFCEVKFKSDQNLQTALELTRRCLIDDREMPVKVEAAIALQVLISNQEKAKEYITPFIRPVMQALLHIIRETENDDLTNVIQKMICEYSEEVTPIAVEMTQHLAMTFNQVIQTGPDEEGSDDKAVTAMGILNTIDTLLSVVEDHKEITQQLEGICLQVIGTVLQQHVLEFYEEIFSLAHSLTCQQVSPQMWQLLPLVFEVFQQDGFDYFTDMMPLLHNYVTVDTDTLLSDTKYLEMIYSMCKKVLTGVAGEDAECHAAKLLEVIILQCKGRGIDQCIPLFVEAALERLTREVKTSELRTMCLQVAIAALYYNPHLLLNTLENLRFPNNVEPVTNHFITQWLNDVDCFLGLHDRKMCVLGLCALIDMEQIPQVLNQVSGQILPAFILLFNGLKRAYACHAEHENDSDDDDEAEDDDETEELGSDEDDIDEDGQEYLEILAKQAGEDGDDEDWEEDDAEETALEGYSTIIDDEDNPVDEYQIFKAIFQTIQNRNPVWYQALTHGLNEEQRKQLQDIATLADQRRAAHESKMIEKHGGYKFSAPVVPSSFNFGGPAPGMN", "length": 1038 }, "evidence": [ { "id": "Q9VSD6", "url": "https://omabrowser.org/oma/group/Q9VSD6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O15397-1", "protein_name": "Importin-8", "gene_name": "IPO8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDLNRIIQALKGTIDPKLRIAAENELNQSYKIINFAPSLLRIIVSDHVEFPVRQAAAIYLKNMVTQYWPDREPPPGEAIFPFNIHENDRQQIRDNIVEGIIRSPDLVRVQLTMCLRAIIKHDFPGHWPGVVDKIDYYLQSQSSASWLGSLLCLYQLVKTYEYKKAEEREPLIIAMQIFLPRIQQQIVQLLPDSSYYSVLLQKQILKIFYALVQYALPLQLVNNQTMTTWMEIFRTIIDRTVPPETLHIDEDDRPELVWWKCKKWALHIVARLFERYGSPGNVTKEYFEFSEFFLKTYAVGIQQVLLKILDQYRQKEYVAPRVLQQAFNYLNQGVVHSITWKQMKPHIQNISEDVIFSVMCYKDEDEELWQEDPYEYIRMKFDIFEDYASPTTAAQTLLYTAAKKRKEVLPKMMAFCYQILTDPNFDPRKKDGALHVIGSLAEILLKKSLFKDQMELFLQNHVFPLLLSNLGYLRARSCWVLHAFSSLKFHNELNLRNAVELAKKSLIEDKEMPVKVEAALALQSLISNQIQAKEYMKPHVRPIMQELLHIVRETENDDVTNVIQKMICEYSQEVASIAVDMTQHLAEIFGKVLQSDEYEEVEDKTVMAMGILHTIDTILTVVEDHKEITQQLENICLRIIDLVLQKHVIEFYEEILSLAYSLTCHSISPQMWQLLGILYEVFQQDCFEYFTDMMPLLHNYVTIDTDTLLSNAKHLEILFTMCRKVLCGDAGEDAECHAAKLLEVIILQCKGRGIDQCIPLFVQLVLERLTRGVKTSELRTMCLQVAIAALYYNPDLLLHTLERIQLPHNPGPITVQFINQWMNDTDCFLGHHDRKMCIIGLSILLELQNRPPAVDAVVGQIVPSILFLFLGLKQVCATRQLVNREDRSKAEKADMEENEEISSDEEETNVTAQAMQSNNGRGEDEEEEDDDWDEEVLEETALEGFSTPLDLDNSVDEYQFFTQALITVQSRDAAWYQLLMAPLSEDQRTALQEVYTLAEHRRTVAEAKKKIEQQGGFTFENKGVLSAFNFGTVPSNN", "length": 1037 }, "evidence": [ { "id": "MGI:2444611", "url": "https://alliancegenome.org/gene/MGI:2444611#orthology", "database": "AGR" }, { "id": "HGNC:9853", "url": "https://alliancegenome.org/gene/HGNC:9853#orthology", "database": "AGR" }, { "id": "FB:FBgn0026252", "url": "https://alliancegenome.org/gene/FB:FBgn0026252#orthology", "database": "AGR" }, { "id": "RGD:1593688", "url": "https://alliancegenome.org/gene/RGD:1593688#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-3#orthology", "database": "AGR" }, { "id": "SGD:S000003893", "url": "https://alliancegenome.org/gene/SGD:S000003893#orthology", "database": "AGR" }, { "id": "SGD:S000002803", "url": "https://alliancegenome.org/gene/SGD:S000002803#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O95373-1", "protein_name": "Importin-7", "gene_name": "IPO7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPNTIIEALRGTMDPALREAAERQLNEAHKSLNFVSTLLQITMSEQLDLPVRQAGVIYLKNMITQYWPDRETAPGDISPYTIPEEDRHCIRENIVEAIIHSPELIRVQLTTCIHHIIKHDYPSRWTAIVDKIGFYLQSDNSACWLGILLCLYQLVKNYEYKKPEERSPLVAAMQHFLPVLKDRFIQLLSDQSDQSVLIQKQIFKIFYALVQYTLPLELINQQNLTEWIEILKTVVNRDVPNETLQVEEDDRPELPWWKCKKWALHILARLFERYGSPGNVSKEYNEFAEVFLKAFAVGVQQVLLKVLYQYKEKQYMAPRVLQQTLNYINQGVSHALTWKNLKPHIQGIIQDVIFPLMCYTDADEELWQEDPYEYIRMKFDVFEDFISPTTAAQTLLFTACSKRKEVLQKTMGFCYQILTEPNADPRKKDGALHMIGSLAEILLKKKIYKDQMEYMLQNHVFPLFSSELGYMRARACWVLHYFCEVKFKSDQNLQTALELTRRCLIDDREMPVKVEAAIALQVLISNQEKAKEYITPFIRPVMQALLHIIRETENDDLTNVIQKMICEYSEEVTPIAVEMTQHLAMTFNQVIQTGPDEEGSDDKAVTAMGILNTIDTLLSVVEDHKEITQQLEGICLQVIGTVLQQHVLEFYEEIFSLAHSLTCQQVSPQMWQLLPLVFEVFQQDGFDYFTDMMPLLHNYVTVDTDTLLSDTKYLEMIYSMCKKVLTGVAGEDAECHAAKLLEVIILQCKGRGIDQCIPLFVEAALERLTREVKTSELRTMCLQVAIAALYYNPHLLLNTLENLRFPNNVEPVTNHFITQWLNDVDCFLGLHDRKMCVLGLCALIDMEQIPQVLNQVSGQILPAFILLFNGLKRAYACHAEHENDSDDDDEAEDDDETEELGSDEDDIDEDGQEYLEILAKQAGEDGDDEDWEEDDAEETALEGYSTIIDDEDNPVDEYQIFKAIFQTIQNRNPVWYQALTHGLNEEQRKQLQDIATLADQRRAAHESKMIEKHGGYKFSAPVVPSSFNFGGPAPGMN", "length": 1038 }, "evidence": [ { "id": "RGD:1310849", "url": "https://alliancegenome.org/gene/RGD:1310849#orthology", "database": "AGR" }, { "id": "MGI:2152414", "url": "https://alliancegenome.org/gene/MGI:2152414#orthology", "database": "AGR" }, { "id": "HGNC:9852", "url": "https://alliancegenome.org/gene/HGNC:9852#orthology", "database": "AGR" }, { "id": "FB:FBgn0026252", "url": "https://alliancegenome.org/gene/FB:FBgn0026252#orthology", "database": "AGR" }, { "id": "SGD:S000003893", "url": "https://alliancegenome.org/gene/SGD:S000003893#orthology", "database": "AGR" }, { "id": "SGD:S000002803", "url": "https://alliancegenome.org/gene/SGD:S000002803#orthology", "database": "AGR" }, { "id": "Q9VSD6", "url": "https://omabrowser.org/oma/group/Q9VSD6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P46970-1", "protein_name": "Nonsense-mediated mRNA decay protein 5", "gene_name": "NMD5", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDITELLQCFACTLDHNAAVRTNAETHLKNASKVPGFLGACLDIIAADEVPENIKLSASLYFKNKITYGWSAGARQGSNELLDSHVDPDEKPVVKDMLIKTMVSVSKTSPRCIRVLKSALTVIISEDYPSKKWGNLLPNSLELLANEDITVTYVGLLCLAEIFRTYRWKNNDERQDLEELILNYFPALLNYGANVLFQDGKYMNNEQIGELVKLIIKIYKFVSYHDLPFTLQRSESFTPWACFFVSIIQQPLPQEVLAISDIEVRSKNPWVKCKKWALANLYRLFQRYASTSLTRKFQYDEFKQMYCEEFLTQFLQVVFDQIEKWGTGQLWLSDECLYYILNFVEQCVVQKTTWKLVGPHYNVILQHVIFPLLKPTAETLEAFDNDPQEYINRNMDFWDVGYSPDLAALALLTTCVTKRGKTTLQPTLEFMVSTLQSAVGDYNNIMLDNALQIESCLRIFSSIIDRLITKDSPFASEMEKFILTYVLPFFKSQYGFLQSRVCDICSKLGSMDFKDPVITSTIYEGVMNCLNNSSNSLPVELTAALALQTFISDDQFNMKLSEHVVPTMQKLLSLSNDFESDVISGVMQDFVEQFAEQLQPFGVELMNTLVQQFLKLAIDLHETSNLDPDSFTNVDSIPDESDKQMAALGILSTTISILLSFENSPEILKNLEQSFYPAAEFILKNDIEDFYRECCEFVENSTFLLRDITPISWKILELIGECNRKPDSMVSYYLSDFMLALNNILIYGRNELKKNEFYTKIIFEIYQKAVTAEDNSLDDLRVVFDLSQELVLALDDSLPQQYRERLLADVVGSILTQKNELKTNVVFSVTAFNVVISNMITEPLITLQYLKQQGCLEIFFQTWITDYIPNYKRCYDIKLSVLALLKIILKLESNDYSVLNLENLVPQLGSIVTQLASRLPTALRQLANQRKEFSSSGFEEDTKWDENFLDVGDDDENDDEGDLTEKYLELIKNRADSLDFVDGYDAKETFDDLEEDPLTGSILDTVDVYKVFKESIANLQHVDSNRYQGILRHLTPADQELFMGIMNA", "length": 1048 }, "evidence": [ { "id": "RGD:1310849", "url": "https://alliancegenome.org/gene/RGD:1310849#orthology", "database": "AGR" }, { "id": "MGI:2152414", "url": "https://alliancegenome.org/gene/MGI:2152414#orthology", "database": "AGR" }, { "id": "MGI:2444611", "url": "https://alliancegenome.org/gene/MGI:2444611#orthology", "database": "AGR" }, { "id": "HGNC:9853", "url": "https://alliancegenome.org/gene/HGNC:9853#orthology", "database": "AGR" }, { "id": "HGNC:9852", "url": "https://alliancegenome.org/gene/HGNC:9852#orthology", "database": "AGR" }, { "id": "FB:FBgn0026252", "url": "https://alliancegenome.org/gene/FB:FBgn0026252#orthology", "database": "AGR" }, { "id": "RGD:1593688", "url": "https://alliancegenome.org/gene/RGD:1593688#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-3#orthology", "database": "AGR" }, { "id": "SGD:S000003893", "url": "https://alliancegenome.org/gene/SGD:S000003893#orthology", "database": "AGR" }, { "id": "Q9VSD6", "url": "https://omabrowser.org/oma/group/Q9VSD6/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q04175-1", "protein_name": "Importin beta SMX1", "gene_name": "SXM1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVQEQAILSCIEQTMVADAKIIKEAEQQLFEFQKQPGFTSFLLNIVSDDNFALNVRLSSAIYLKNKIHRSWDTKREDGIKADEKLSIKERLIETLVKNCENNHIRPILTETINGILVGQEDWDLAPIIKNLLSSGDASYIYPGLLLLFQLCKAHRWDMVGSRDYIDSVIEELFPIVEGIASNIGSQTDYRSNEILYLILKSFKYACLNNLPQYFSQPERIMSWVQLHLYLCSKPLPVEVMELDPADRSLDKRVKVNKWGFGNLNRFLQRYNKITKAITKEFIDYIFNTIVPIILREFFKDIEAWGNNSLWLSDSSLYFLISFLEKCVTIDQLYPLIEPHLQIIFENVIFPCLCANEQSIELLEDDQEEYTRRYFDINREGSTPDAASADFIFLIGSKRPEKLNNILPFINDIFTRFDANSSDINMAFKEEGALRTLSNLFSFIDEPSVLENIFGHFIVPLLSQDKYMFLVARSLETIALYSEEFKDMNILSQLFELTYTNFLNSNVLPVQIEAADAIKCLIVSNPQIHPAVSAHVPGMMEKLLKLSKIFEIDILSEVMEALVERFSDELSPFAKDLASNLVEQFLRIAQALVENPSETYSASDQEQEIQASGLLQTMTTMVMSMNKVPLIESLAPVVKFVVLHAQISFITEAVDLLDALTISSHLLYNQIAPPIWELLHDILDSFQTYAMDYFEAYSIFFETIVMTGFPQDQTYVQPLLEILSAKLESEVDYDIEHVMQILMYFALSMRDIPLFSKAIKVSTNDELGLDSKCIVKLGLANLFAKPIETLQIMENEGFTINFFTNWFNEKFYSVFAIKLQVLVILTLLKMPEVPNSVSPLLNNLTNKLVELTLSLPKAIRNRDAVTEGKSLEGDLTPEEEEEYFIECDDDMKETVLDQINVFQEVHTFFKNLQNEDAGKYEKIINYLDESKRDSLQVILEFVSQH", "length": 944 }, "evidence": [ { "id": "RGD:1310849", "url": "https://alliancegenome.org/gene/RGD:1310849#orthology", "database": "AGR" }, { "id": "MGI:2152414", "url": "https://alliancegenome.org/gene/MGI:2152414#orthology", "database": "AGR" }, { "id": "MGI:2444611", "url": "https://alliancegenome.org/gene/MGI:2444611#orthology", "database": "AGR" }, { "id": "HGNC:9853", "url": "https://alliancegenome.org/gene/HGNC:9853#orthology", "database": "AGR" }, { "id": "HGNC:9852", "url": "https://alliancegenome.org/gene/HGNC:9852#orthology", "database": "AGR" }, { "id": "FB:FBgn0026252", "url": "https://alliancegenome.org/gene/FB:FBgn0026252#orthology", "database": "AGR" }, { "id": "RGD:1593688", "url": "https://alliancegenome.org/gene/RGD:1593688#orthology", "database": "AGR" }, { "id": "SGD:S000002803", "url": "https://alliancegenome.org/gene/SGD:S000002803#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q55CX9-1", "protein_name": "Probable importin-7 homolog", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDPIIQTIQLFQHTLHHDANVIKAAEAQLQQIKVTDGYSRILLKILASNEVDISIRQGVSIFLKNMIITKWRGAEDESPITQEDAEFIKENLIDLLVHSHHLVQNQIEAMIEIIANRDFPEKWTSLLPKSIQYINTQDVKLILAGLTSIQLGIKRFRYVTMGDKKKELLYTIVNEIFPLLLQILEFLSQHQTIESALMQKKVIKIFGYAIHFEIPDLLIQPEVFNKWLSQFVRIIQRPITPQENVKHADDCRKNQWWLLKRTTAKLLNLLFRKSATSVRSTDHSSVKALNKLFMPVYSVEVMKVFYEQLSTLEQLYKGVHYERYQQKLIEYFSFAIKYGVTYVAMKPWLSTLIQQVLFPIICFNDRDAELWECDPNEFLRSQFESSMTFATARIEVLNFIIDVVGKRGRANLDMIMGFCIQSLNKYNAATNASEKNPREKDGVLVIISVLSAYLKNISFYKSNLEQMLLLHVFPELSSPHGFLKARACSLFSEFYNIEFTDPVYFSNALKLILGLMSDNDLPVRVKAGTSICNLVRANQGVDELRPILPQLLDKIFSLLSEAESEDLVIAIESIIQRFKHEIAPYAVNLCKNLSEQFLRLLELEESDESGESGFASQECLGVYCTLLRALKDIPDVFNSLEQQIVPILQKLFTSDHMMYLDEALRILTFVTYYPKSISPLVWSLFPQIMNLFDECACDFASSYVNPLDNYISYGTEYFLSNQQYIEMVFNMYKKMVGDINQQPVDAGDCCKIMESLIQRAKGRIDYMIVPVLELACGRLLNTDKNNQKSKEFTVYLLEIIANCIYYNPLISTQYLESKNLVEPIFGLWFNRIKHFQRFYDKKISVLAFSSLLTLNPSPNFVKFGTSLILEKMLQFTKDMLSIEKELDKQEAEREQKIKDGTLKPEEEEFIDENDEEDYFDNHKFEFEFTEIPDNQDCQHDDEGEVFLDDIEKATEYFENGGDLGEDEGDNFDDQNDDDDQDSEEDLFEDEDTPDFETPIDEVDGFEFMINSIQNFFQINPTCIQQISEKQQEKIKKYVASAPARKEKLRLEKEKEEKLKQQQQKK", "length": 1065 }, "evidence": [ { "id": "Q9VSD6", "url": "https://omabrowser.org/oma/group/Q9VSD6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q7TMY7-1", "protein_name": "Importin-8", "gene_name": "Ipo8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLNRIIQALKGTIDPKLRIAAETELNQSYKIINFAPSLLRIIVSDHVEFPVRQAAAIYLKNMVTQYWPDREPPPGEVIFPFNIHENDRQQIRDNIVEGIIRSPDLVRVQLTMCLRVIIRHDFPGHWPAVVDKIDYYLQSPNSGSWLGSLLCLYQLVKTYEYKKAEEREPLLAAMQIFLPRIQQQILQLLPDASHYSVLLQKQILKIFYALVQYALPLQLVNHQTMTTWMEIFRTIIDRTVPPETLQIDEDDRPELVWWKCKKWALHIVARLFERYGSPGNVTKEYFEFSEFFLKTYAVGIQQVLLKILDQYRQKEYIAPRVLQQAFNYLNQGVVHAVTWKQMKPHIQNISEDVIFSVMCYKDEDEELWQEDPYEYIRMKFDIFEDYASPTTAAQTLLYTAAKKRKEVLPKMMAFCYQILTDPNFDPRKKDGALHVIGSLAEILLKKSLFKDQIELFLQNHVFPLLMSNLGYLRARSCWVLHAFSSLKFHNELNLRNAVELAKKSLIEDEEMPVKVEAALALQSLISNQAQAKEHMKPYVRFIMQELLHIVRETENDDVTNVIQKLICEYSQDVASIAVDTTQHLAEIFGKVLQSDEYEEIEDKTVMAMGILHTIDTILTVVEDHPEIIQQLENICLRIIDLVLQKHVIEFYEEILSLAYNLTCHTISPQMWQLLGILYEVFQQDCFEYFTDMMPLLHNYVTVDTNALLSNPKHLEVLFTMCRKVLCGEAGEDAECYAAKLLEVIILQCKGRGIDQCIPLFIQLVLERLTRGVKTSELRTMCLQVAIAALYYSPELLFHTLEQVQLPHNPGPVTSQFINQWMNDTDYFLGHHDRKMCIIGLSVLLELQNRPPAVDAVAAQILPSILFLFLGLKQVCATRQTVNRENHSKAEKVDIEENEEISSEEEEETSVSAQAMQSQIGRSEEEDDDDWDEEVLEETALEGFSTPLDLDNSVDEYQFFTQALLTVQNRDAAWYQLLVAPLSEDQKRKLQEVYTLAEHRRTLAAGQFHI", "length": 1010 }, "evidence": [ { "id": "MGI:2444611", "url": "https://alliancegenome.org/gene/MGI:2444611#orthology", "database": "AGR" }, { "id": "HGNC:9853", "url": "https://alliancegenome.org/gene/HGNC:9853#orthology", "database": "AGR" }, { "id": "FB:FBgn0026252", "url": "https://alliancegenome.org/gene/FB:FBgn0026252#orthology", "database": "AGR" }, { "id": "RGD:1593688", "url": "https://alliancegenome.org/gene/RGD:1593688#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-3#orthology", "database": "AGR" }, { "id": "SGD:S000003893", "url": "https://alliancegenome.org/gene/SGD:S000003893#orthology", "database": "AGR" }, { "id": "SGD:S000002803", "url": "https://alliancegenome.org/gene/SGD:S000002803#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EPL8-1", "protein_name": "Importin-7", "gene_name": "Ipo7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPNTIIEALRGTMDPALREAAERQLNEAHKSLNFVSTLLQITMSEQLDLPVRQAGVIYLKNMITQYWPDREATPGDIAPYTIPEEDRHCIRENIVEAIIHSPELIRVQLTTCIHHIIKHDYPSRWTAIVDKIGFYLQSDNSACWLGILLCLYQLVKNYEYKKPEERSPLVAAMQHFLPVLKDRFIQLLSDQSDQSVLIQKQIFKIFYALVQYTLPLELINQQNLTEWVEILKTVVNRDVPNETLQVEEDDRPELPWWKCKKWALHILARLFERYGSPGNVSKEYNEFAEVFLKAFAVGVQQVLLKVLYQYKEKQYMAPRVLQQTLNYINQGVSHALTWKNLKPHIQGIIQDVIFPLMCYTDADEELWQEDPYEYIRMKFDVFEDFISPTTAAQTLLFTACSKRKEVLQKTMGFCYQILTEPNADPRKKDGALHMIGSLAEILLKKKIYKDQMEYMLQNHVFPLFSSELGYMRARACWVLHYFCEVKFKSDQNLQTALELTRRCLIDDREMPVKVEAAIALQVLISNQEKAKEYITPFIRPVMQALLHIIRETENDDLTNVIQKMICEYSEEVTPIAVEMTQHLAMTFNQVIQTGPDEEGSDDKAVTAMGILNTIDTLLSVVEDHKEITQQLEGICLQVIGTVLQQHVLEFYEEIFSLAHSLTCQQVSPQMWQLLPLVFEVFQQDGFDYFTDMMPLLHNYVTVDTDTLLSDTKYLEMIYSMCKKVLTGVAGEDAECHAAKLLEVIILQCKGRGIDQCIPLFVEAALERLTREVKTSELRTMCLQVAIAALYYNPHLLLNTLENLRFPNNVEPVTNHFITQWLNDVDCFLGLHDRKMCVLGLCALIDMEQIPQVLNQVSGQILPAFILLFNGLKRAYACHAEHENDSDDDEDAEDDDETEELGSDEDDIDEDGQEYLEILAKQAGEDGDDEDWEEDDAEETALEGYSTIIDDEDNPVDEYQIFKAIFQTIQNRNPVWYQALTHGLNEEQRKQLQDIATLADQRRAAHESKMIEKHGGYKFSAPVVPSSFNFGGPAPGMN", "length": 1038 }, "evidence": [ { "id": "RGD:1310849", "url": "https://alliancegenome.org/gene/RGD:1310849#orthology", "database": "AGR" }, { "id": "MGI:2152414", "url": "https://alliancegenome.org/gene/MGI:2152414#orthology", "database": "AGR" }, { "id": "HGNC:9852", "url": "https://alliancegenome.org/gene/HGNC:9852#orthology", "database": "AGR" }, { "id": "FB:FBgn0026252", "url": "https://alliancegenome.org/gene/FB:FBgn0026252#orthology", "database": "AGR" }, { "id": "SGD:S000003893", "url": "https://alliancegenome.org/gene/SGD:S000003893#orthology", "database": "AGR" }, { "id": "SGD:S000002803", "url": "https://alliancegenome.org/gene/SGD:S000002803#orthology", "database": "AGR" }, { "id": "Q9VSD6", "url": "https://omabrowser.org/oma/group/Q9VSD6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "U4 snRNA binding", "id": "GO:0030621", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030621", "evidence": [ { "database": "UniProtKB", "id": "Q9VSD6", "url": "https://www.uniprot.org/uniprotkb/Q9VSD6" } ], "pmid": "" }, { "name": "U2 snRNA binding", "id": "GO:0030620", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030620", "evidence": [ { "database": "UniProtKB", "id": "Q9VSD6", "url": "https://www.uniprot.org/uniprotkb/Q9VSD6" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "Q9VSD6", "url": "https://www.uniprot.org/uniprotkb/Q9VSD6" } ], "pmid": "" }, { "name": "U1 snRNA binding", "id": "GO:0030619", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030619", "evidence": [ { "database": "UniProtKB", "id": "Q9VSD6", "url": "https://www.uniprot.org/uniprotkb/Q9VSD6" } ], "pmid": "" }, { "name": "nuclear import signal receptor activity", "id": "GO:0061608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061608", "evidence": [ { "database": "UniProtKB", "id": "Q9VSD6", "url": "https://www.uniprot.org/uniprotkb/Q9VSD6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 12, "go_terms": [ { "name": "compound eye development", "id": "GO:0048749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048749", "evidence": [ { "database": "UniProtKB", "id": "Q9VSD6", "url": "https://www.uniprot.org/uniprotkb/Q9VSD6" } ], "pmid": "" }, { "name": "negative regulation of neuron apoptotic process", "id": "GO:0043524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043524", "evidence": [ { "database": "UniProtKB", "id": "Q9VSD6", "url": "https://www.uniprot.org/uniprotkb/Q9VSD6" } ], "pmid": "" }, { "name": "Cajal body organization", "id": "GO:0030576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030576", "evidence": [ { "database": "UniProtKB", "id": "Q9VSD6", "url": "https://www.uniprot.org/uniprotkb/Q9VSD6" } ], "pmid": "" }, { "name": "protein 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"Protein Classification" ] }, { "id": "Q9VSE2", "url": "https://alphafold.ebi.ac.uk/entry/Q9VSE2", "database": "AlphaFoldDB", "categories": [] }, { "id": "FBgn0002899", "url": "https://bgee.org/?page=gene&gene_id=FBgn0002899", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18026", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18026", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18795", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18795", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0002899", "url": "https://flybase.org/reports/FBgn0002899", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "38905", "url": "https://www.ncbi.nlm.nih.gov/gene/38905", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VSE2", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VSE2*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR001650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011545", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011545", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046931", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046931", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048960", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048960", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050474", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050474", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG7972", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG7972", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MFLNANI", "url": "https://omabrowser.org/oma/group/MFLNANI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VSE2", "url": "https://www.orthodb.org/?gene=Q9VSE2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47961", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47961", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47961:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47961:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00270", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00270", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20470", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20470", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21099", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21099", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q9VSE2", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q9VSE2", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_648178", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648178", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q9VSE2", "url": "https://www.uniprot.org/uniprotkb/Q9VSE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VSE2-1", "url": "https://www.uniprot.org/uniprotkb/Q9VSE2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MANKHNLCKKRSLDLSEESTSESHAKRQCTENLFWPEGEDDDSFFSNAHLEDLLDGRKEELFGTQATTSTNKMTQSGSDDGLGLFADTSFPSAQSVPPNSASKPDEASAPTDKHQIDLADEENADKLFKKINLNDLSIAEMEDIFHGADDFSDPMVQNTQLFLDAMTFKKPKTPEKLLAPLKDDSMSFISKSVIEGLVQGTQYVTCEELKNQSLLDPVNWETQAFADFEKNNQDIDKFPSKGEFYGLPDKVKKMILEHKGINSLYEWQDECLNLPAIRQRKNLIYALPTSGGKTLVAEILMLRELLCRERNVLFILPYVSIVQEKVSAMSPFAIDLDFIVEEYTAGKGKCPPQPRRKRRSLFIASIEKGAVLMDSLIDVQRPHEIGLVVVDELHLIGEKGRGATLEAFLTKVMFLNANIQIVGMSATIGNLSEISSFLNADVYTRGFRPVELKEYIKCGPDLLEINSAGQTLEEIFVPSRSVEYNYSEAVKRADPDHLAGLISECAPEHCCLVFCPSRKNCENVALLLSRIVPKHKFFEHRRSEKLDLMDALDKMCGILSPVLAKTLPYGIAYHHSGLTTDERKYIETAYRFGVVTVICCTSTLAAGVNLPAKRVIIRAPYVGQEFLTLCKYKQMVGRAGRAGLGEAGESILIAQSKDNLLVGQMLFSPMDKALSSLDQNEAVGLQSLILSVVGLNLAECRRDLNRLVNSTLLSVQAKSLEVAVNEIVLRILREMFKNKVLQLAEPQAKSKINSSDIITSQDVSQANRPAGDRRLLIGQSTPFKLTNIGRAAFKAGIDYKRANAIHKELKQAQQQLILTNYLHLLYLVVCFNSNERGDELFPADASILFGVYTSLPLDSQAMFKQLGFTEAHAARLFKTQSVQGPLSLQLNRLYKVLILADILNLLPIPSVASKYNVERGTLQHLISQSTAAASAIVRLCEELEEFWCYKPLFERILHKMDRCGTFELEPLMELPAVKINRARQLYAAGFQTIGDIARVRPSHLVQSLEHMPLRVATEIVSAAKIILMKKLDHLEEETENLKDCLKTSDKN", "length": 1051, "header": "sp|Q9VSE2-1|HELQ_DROME Isoform 1 of Helicase POLQ-like OS=Drosophila melanogaster OX=7227 GN=mus301 PE=1 SV=1 CANONICAL=Q9VSE2-1" }, "isoforms": [ { "isoform_ac": "Q9VSE2-1", "url": "https://www.uniprot.org/uniprotkb/Q9VSE2/entry#Q9VSE2-1", "sequence": { "sequence": "MANKHNLCKKRSLDLSEESTSESHAKRQCTENLFWPEGEDDDSFFSNAHLEDLLDGRKEELFGTQATTSTNKMTQSGSDDGLGLFADTSFPSAQSVPPNSASKPDEASAPTDKHQIDLADEENADKLFKKINLNDLSIAEMEDIFHGADDFSDPMVQNTQLFLDAMTFKKPKTPEKLLAPLKDDSMSFISKSVIEGLVQGTQYVTCEELKNQSLLDPVNWETQAFADFEKNNQDIDKFPSKGEFYGLPDKVKKMILEHKGINSLYEWQDECLNLPAIRQRKNLIYALPTSGGKTLVAEILMLRELLCRERNVLFILPYVSIVQEKVSAMSPFAIDLDFIVEEYTAGKGKCPPQPRRKRRSLFIASIEKGAVLMDSLIDVQRPHEIGLVVVDELHLIGEKGRGATLEAFLTKVMFLNANIQIVGMSATIGNLSEISSFLNADVYTRGFRPVELKEYIKCGPDLLEINSAGQTLEEIFVPSRSVEYNYSEAVKRADPDHLAGLISECAPEHCCLVFCPSRKNCENVALLLSRIVPKHKFFEHRRSEKLDLMDALDKMCGILSPVLAKTLPYGIAYHHSGLTTDERKYIETAYRFGVVTVICCTSTLAAGVNLPAKRVIIRAPYVGQEFLTLCKYKQMVGRAGRAGLGEAGESILIAQSKDNLLVGQMLFSPMDKALSSLDQNEAVGLQSLILSVVGLNLAECRRDLNRLVNSTLLSVQAKSLEVAVNEIVLRILREMFKNKVLQLAEPQAKSKINSSDIITSQDVSQANRPAGDRRLLIGQSTPFKLTNIGRAAFKAGIDYKRANAIHKELKQAQQQLILTNYLHLLYLVVCFNSNERGDELFPADASILFGVYTSLPLDSQAMFKQLGFTEAHAARLFKTQSVQGPLSLQLNRLYKVLILADILNLLPIPSVASKYNVERGTLQHLISQSTAAASAIVRLCEELEEFWCYKPLFERILHKMDRCGTFELEPLMELPAVKINRARQLYAAGFQTIGDIARVRPSHLVQSLEHMPLRVATEIVSAAKIILMKKLDHLEEETENLKDCLKTSDKN", "length": 1051, "header": "sp|Q9VSE2-1|HELQ_DROME Isoform 1 of Helicase POLQ-like OS=Drosophila melanogaster OX=7227 GN=mus301 PE=1 SV=1 CANONICAL=Q9VSE2-1" }, "locus": { "chromosome": "3L", "start_pos": 8137808, "end_pos": 8142014, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0076689", "url": "https://www.ensemblgenomes.org/id/FBtr0076689" }, { "database": "Ensembl Peptide", "id": "FBpp0076412", "url": "https://www.ensemblgenomes.org/id/FBpp0076412" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE2", "url": "https://www.uniprot.org/uniprotkb/Q9VSE2" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE2", "url": "https://www.uniprot.org/uniprotkb/Q9VSE2" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "Drosophila mus301/spindle-C encodes a helicase with an essential role in double-strand DNA break repair and meiotic progression.", "journal": "Genetics", "date": "2006", "authors": "McCaffrey R, St Johnston D, Gonzalez-Reyes A", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE2", "url": "https://www.uniprot.org/uniprotkb/Q9VSE2" } ], "reference": [ { "type": "PubMed", "id": "16888338", "url": "https://glygen.org/publication/PubMed/16888338" } ] }, { "title": "Oocyte determination and the origin of polarity in Drosophila: the role of the spindle genes.", "journal": "Development", "date": "1997", "authors": "Gonz\u00e1lez-Reyes A, Elliott H, St Johnston D", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE2", "url": "https://www.uniprot.org/uniprotkb/Q9VSE2" } ], "reference": [ { "type": "PubMed", "id": "9362456", "url": "https://glygen.org/publication/PubMed/9362456" } ] } ], "pathway": [ { "id": "dme:Dmel_CG7972", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG7972", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1LQC3-1", "protein_name": "Helicase POLQ-like", "gene_name": "HELQ", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDEGGSRIRRRVSVRKRNRPSLESVFAASPATELKHSDEEKDDDEMVAGSRRRKTVDVQPVEVQPHHLSDSRVPRFNGRLRIRIPASLGVQLMSIIDSEEDMFAQVDDLEQKYLQLPEHRNHATDHANEDLCSESDKHNTLNVTVVGDCTELNIGDHTKNQSRHEDVSIEPEADILYDVPSSQVLFFENLHNSSSDLGGPSTEEKDWNSSFPKTVNEELPVNSREQPQQTVESSSKIRTSSDANRGKSLKDHLKSTMTGNAKAQTPIFSRTKQLKETLLSEEINVAKKTIESSSDDLGPFYSLPSKVRDLYVQFKGIEKLYEWQHTCLTLKSVQERKNLIYSLPTSGGKTLVAEILMLQELLCRRRDVLMILPYVAIVQEKISGLSSFGIELGFFVEEYAGSKGKFPPIKRREKKSLYIATIEKGHSLVNSLIETGRISSLGLVVVDELHMIGEGTRGAILEMTLAKILYTSKTTQIIGMSATLNNVEDLQKFLQAEYYTSQFRPVELKEYLKINDTIYEVNSRAENGMTFSRLLNYKYSDTLKKMDPDHLVALVTEVIPSYSCLVFCPTKKNCENIAEMICKSLSKEYLKHKEKEKQEVIQNLKNVSGGNLCRVLRHTIPFGVAYHHSGLTSDERKLLEEAYSTGVLCLFTCTSTLAAGVNLPARRVILRAPYVAKEFLKRNQYKQMIGRAGRAGIDSVGESILILQEKDKQQVLQLISKPLENCYSHLVQEFTKGIQTLFLSLIGLKIATNLDDIYRFMSGTFFGVQQKVLLKEKSLWEITMESLRYLTEKGLLQKDTMCGSKEEFQNNFHITKLGRASFKGTIDLAYCDILYRDLKKGLEGLMLESLLHLIYLTTPYDMASQCDPDWMIYFRQFNQLSPAEQNVAALVGVSENFIGKKASGQAIRKKVDKNIVNRLYLSFILYTLLKETNIWSVSEKFNMPRGYIQSLLSAAAAFSSCVLHFCEELEEFWVYRALLGELTKKLTYCVKAELIPLMEVTGVLEGRARQLYNAGYKSLTHLANANPEVLIRTIDHLSRRQAKQIVSSAKMLLHEKAEALQEEVEELLRLPSDFPGLVASSTEKA", "length": 1085 }, "evidence": [ { "id": "Q9VSE2", "url": "https://omabrowser.org/oma/group/Q9VSE2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8V0XG98-1", "protein_name": "Helicase POLQ-like", "gene_name": "HELQ", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAEPALAVRRRSRISSARKRSHPPAQPGATSSPLARKRPSGGGEGTPAEPLCNNDSEEDMFGDYDSFHESDSLLAQVLDAEPQHSQEKGLDVKAAGRFAHGNLQSEMDQSKQGNLHAAGDSSVRKVDEHYGFQMNENDAGDADEDLSDSVFDELPSSQLLYLEKTRELSSRSQRSAGTERMDKWENSSLDKIQCPSSPCPDSGHKNRSTKSSKGSVCDSCKSVSLKDHLKNALTGNAKAQTPKVSKTKQLKEAILSEEISVARETIGSSSFDIGPFYGLPSKVKHLLRQFRGIETLYEWQHDCLTLKSLQQRKNLIYSLPTSGGKTLVAEILILQELLCRQKDVLMILPYVAIVQEKVWGLSSFGIELGFLVEEYAGSKGRFPPIKRRIKKSLYIATIEKGHALVNSLIETDRIDDLGLVVVDELHMIGEGSRGAVLEMTLAKILYASKNTHVVGMSATLNNVGDLQKFLQAEYYTKNFRPVELKEYIKIRDTIYEVDSKAENGFTFSRLLNFKYSSSLEKADPDHIVALVTEVIPKYSCLIFCPTKKNCENVATMVCKYLNKEFRAHREKEKQDLIKNLKDIGNGSICPVLRQTIPFGVAYHHSGLTNDERKSIEEAYSRGVLCLLACTATLAAGVNLPARRVILRAPYVASEFLKKNQYKQMIGRAGRAGIDNAGESILVVQEKDKHLVRDLITSPLENCYSNLLPEITKGMQYLLLSLVGLKIAVTQEEVYSFMCHTLLGVQQQLLLKEKSLSEIVRDELENLIEKGLLKGKIMEKDQNSKSTLTVTLLGKATYKGSIDVSYCNLLYKELRKGLEGLVLESSLHLLYLATPYDMVSNCSPDWMIYLRQFNQLSSAEQKVADMVGVPESFIAKKASGQAIRKNVDSTAVNRLYLSFVLYALLKETNVWSVSEKFNMSRGYVQNLLTSAASFASCILHFCEELEEFWVYKALLTELTKRLTYCVKTELIPLMEVAGVLEARAKQLYNAGYKTLAHLANANPETLVKTIEHLSRRQAKQMVSSAKMLLSEKAEALQEEVEELLKVPTDIP", "length": 1050 }, "evidence": [ { "id": "Q9VSE2", "url": "https://omabrowser.org/oma/group/Q9VSE2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E9PT19-1", "protein_name": "Helicase POLQ-like", "gene_name": "Helq", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEESSPRIRRRVSLRKRNRRSLESLGAARAPAELQPAEDTEDEAAAGSRRRKTGSPEPAQENDSEEDMFGDYNSFSENSFLAQVDDLEQKYIQLPDCGSRGTDSGTKDLCSEGLGNSLSVPAVDFTDSETREYIKKQGDLDVPVEPEVGGDLSFDMPSSQILYFESMQNSSKDLGDQSTKGRDGKSSNEELHHSHREQPQPKSDFSDVGGSSEASRRRSIKDCLKSAMTGNARAQTPAFPRSKQLRETLLSEEISVARKAIESPSDDLGPFYSLPSKVRDLYAQLKGIKRLYDWQHTCLTLSSVQERKNLIYSLPTSGGKTLVAEILMLQELLCRQKDVLLILPYVAIVQEKISSLSSFGIELGFFVEEYAGSKGRFPPIKRREKKSLYIATIEKGHSLVNALIETGRMGTLGLVVVDELHMIGEGSRGATLEMTLAKVLYTSKTTQIIGMSATLNNVEDLQAFLKAEYYTSQFRPVELKEFLKVNDTIYEVDSRAVDGMTFSRLLNYKYSDALKKVDPDRLVALVTEVIPNYSCLVFCPSKKNCENVAEMLCKFLSRDYLNHREEEKGELIKSLRNVGHGKVCPVLKRTIPFGVAYHHSGLTSDERKLLEEAYSTGVLCLFTCTSTLAAGVNLPARRVILRAPYVANTFLKRNQYKQMIGRAGRAGIDTAGESILLLQEKDKQQVLGLINGPLEDCHSHLVEEFTKGIQSLFLSLIGLKIAESLGDIYQFMNGTLFGVQQKTLLREKSLWEVTVGALEHLTEKGLLQKDSHGSPEESRCHFRITKLGQASFKGAIDLTYCDTLYRDLKKGLEGLVLESLLHLVYLTTPYDLAAQSEPDWMVYFRQFSQLSPAEQSVATLLGISESFIGRKASGQAIRKKVDKNAVNRLYLSFVLYSLLKETNVWSVSERFNMPRGYIQNLLMGAASFSSCVLHFCEELEEFWVYKALLTELTKKLTYCVKAELIPLMEVTGVLEGRAKQLYSAGYRSVVHLANANPEVLVKTIDHLSRRQAKQIVSSAKMLLHEKAEALQEEAEELLRLPADLPGLGGPGSERAGSHAGDLALR", "length": 1065 }, "evidence": [ { "id": "RGD:1560216", "url": "https://alliancegenome.org/gene/RGD:1560216#orthology", "database": "AGR" }, { "id": "HGNC:18536", "url": "https://alliancegenome.org/gene/HGNC:18536#orthology", "database": "AGR" }, { "id": "MGI:2176740", "url": "https://alliancegenome.org/gene/MGI:2176740#orthology", "database": "AGR" }, { "id": "FB:FBgn0002899", "url": "https://alliancegenome.org/gene/FB:FBgn0002899#orthology", "database": "AGR" }, { "id": "Q9VSE2", "url": "https://omabrowser.org/oma/group/Q9VSE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1Q4P2-1", "protein_name": "Helicase POLQ-like", "gene_name": "helq", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MYTDNQLHDIVVKRNTSSSRKRSRDGVRSHVTPAKKRSSFTSTTCLADKEQIYTQDMAENEGVELCCSDNEDLFEGYDSIVADSSFLAKLEDVELQTRQCYDQQTPNACADDLSDSMLAEDFRDSSPRALPSSQLEFQKAITMPHKSPSRGAPSSSTPYLMNPGPAVNHADLSVNKPHPKARRSMKDHLKKVLMDNAATASTVSKMVQQKEAVMNEEMSFAMQAMESITSEGDLGPFFGLPSKVKDLIFRLKGIQDLYEWQKTCLSLDSIQQRRNLIYSLPTSGGKTLVAEILIFKELLCRKKDALLILPYISLVQEKVRGLSSFGIELDFLVEEYAGSKGKFPPVKRRNKNSLYITTIEKGHSLVNSLIENDRLDNIGLVVVDELHMLGDGSRGAILEMTLSKILYMSKSTQVIGMSATLGNVKDLQSFLRAENYTNNFRPVELKEYVKIKDSIYEVDPKEEACFTFSRLLNFKYSSGMQKMDPDHIIALATEVIPQQSCLIFCATKKNCENLAGMICKYLNKEFIKHKEAEKAILLGELKSSGNGSLCPVLQKTIPFGLAYHHSGLTSDERKLVEEAYSSGVLCLLTCTSTLAAGINLPARRVILRSPYVAADFLKRSQYKQMVGRAGRAGIDAMGESILILQDKDINTAKKLLCAPMEKCYSNLLHDGGRGLLSLILSLIGLKITTTVEQVKDLMKGTFLGVQEAQVSPEKSLWDLTVESIQTLKQKNLIEVSSDENNQNILQITRLGRATYKGSVDLSYCDVLYRDLSKGLEGLLLNSFLHLVYLVTPYDMVHQCKPDWMIYFRQFTNLSAAEQKMATTVGVPESFVARKAAGQSVRKSVDVVVVNRLYLALVLFSLLKETNLWIVSERFQLTRGFVQTLLSSASAFGSSVLHFTEELEEFWAYKALLSELTRRLTYCVQAELIPLMEVSGVLEHRAKQLYSAGYKTLSHLANADPQTLVQTIENLFKKQAYQIIASAKMLLTEKAEALQEEVDDLLMLPLDLPSL", "length": 1010 }, "evidence": [ { "id": "HGNC:18536", "url": "https://alliancegenome.org/gene/HGNC:18536#orthology", "database": "AGR" }, { "id": "MGI:2176740", "url": "https://alliancegenome.org/gene/MGI:2176740#orthology", "database": "AGR" }, { "id": "Q9VSE2", "url": "https://omabrowser.org/oma/group/Q9VSE2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RVE2-1", "protein_name": "Helicase POLQ-like", "gene_name": "HELQ", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDDGGSRIRRRVSVRKRNRFSTESVLAAPTAAELKPGDEKEEEEMVAGSRRRKTVDVQPVENIDSEEDMFGDYDSFAENSFLAQVDDLEQKYMQIPEQEEHATDHAPEDLCSESIKHSILSSNTVGDFTGVKTEEHTKNQSGHEDVATEPEADLLYDVPSSQMLFFEHLHSSSNNLGDPSLKERDRGSSSHKTVNEELPVSSIEEPQQIDDSSSKVRTSSDGNRRQSLKDHLKSAMAGNARAHTSVFSRTKQLKETLLSEEINVAKKTIASSSDDLGPFYSLPSKVRDLYAQFRGIEKLYEWQHTCLTLKSVQERKNLIYSLPTSGGKTLVAEILMLQELLCRRKDALMILPYVAIVQEKIAGLSSFGIELGFFVEEYAGSKGKFPPIKRREKKSLYIATIEKGHSLVNSLIETGRIGGLGLVVVDELHMIGEGSRGATLEMTLAKILYTSKTTQIVGMSATLNNVEDLQAFLRAEYYSSWFRPVELKEYLKINDTIYEVDSKAENGMTFSRLLNYKYSDTLKKLDPDHLVALVTEVIPNHSCLVFCPTKKNCENVAEMICKILSKEYLKHREKEKHELLKNLKAISGGSVCPVLKHTIPFGVAYHHSGLTNDERKLLEEAHSAGVLCLLTCTSTLAAGVNLPAQRVILRAPYVAKEFLKRNQYKQMIGRAGRAGIDSVGESILIFQEKDKQQVLELISRPLENCYSRLVQEFTKGIQTLFLSLIGLKIATTLGDIYHFMSGTFFGVQQKILLKEKSLWEITVESLRYLTEKGLLQKDTVLTEKGLLQKDTVQGSEEEFQYSFRITKLGRASFKGTIDLAYCDILYRDLKKGLEGLVLESLLHLIYLTTPYDMASRCDPDWMVYFRQFSQLSPAEQNVATLVGVSENFIGKKASGQAIKKKVDKTIVNRLYLSFVLYTLLKETSVWRVSEKFNMPRGHIQNLLSGAAAFSSCVLHFCEELEEFWVYRALLVELTKKLTYCVKAELIPLMEVAGVLEGRAKQLYNAGYKSLAHLANADPEVLIRTIDHLSRRQAKQIVSSAKMLLHEKAEALQEEVEELLRLPSDFPSITASSIEKA", "length": 1076 }, "evidence": [ { "id": "Q9VSE2", "url": "https://omabrowser.org/oma/group/Q9VSE2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q2VPA6-1", "protein_name": "Helicase POLQ-like", "gene_name": "Helq", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDGCPRIRRRVSVRKRNRGNLENLRASPTPAELQPAEDTEDEAAAGSRRRKTGSPEHAQENDSEEDMFGDYDSFTESSFLAHVDDLEQRYMQLPECGDRDADSGTKDLCSAGLKNNLRVTTVINLTDPETSEHGQKQSHLDVPAEPEPGSDLSFDVPSSQILYFENPQNSPEALGDPCTKKTNGDPQKSSHEELVSSHTEQPEPNNDFSNVRAASESSRRKSLKDHLKSTMAGNARAQTPAFPRSKHLREALLSEEISVAKKAIESPSDDLGPFYSLPSKVRDLYVQLKGIKKLYDWQHTCLTLRSVQERKNLIYSLPTSGGKTLVAEILMLQELLCRQKDVLMILPYVAIVQEKISSLSSFGIELGFFVEEYAGSKGRFPPIKRREKKSLYIATIEKAHSLVNALIETSRLSTLGLVVVDELHMIGEGSRGAILEMTLAKVLYTSKTTQIIGMSATLNNVEDLQAFLKAEYYTSQFRPVELKEFLKVNDTIYEVDSQAADGMTFSRLLSYKYSEALKKMDPDRLVALVTEVIPNYSCLVFCPSKKNCENVAEMLCKFLSKDYLNHREKEKCEVIKSLRNIGNGKVCPVLKRTVPFGIAYHHSGLTSEERKLLEEAYSTGVLCLLTCTSTLAAGVNLPARRVILRAPYVANTFLKRNQYKQMVGRAGRAGIDTAGESILLLQEKDKQQVLELISGPLETCCSHLVEEFTKGIQALFLSLIGLKIAASLGDIYQFMSGTFFGVQQKILLKEKSLWEITVDALEHLTEKGLLQKDSCGDNEGLECHFRITKLGQASFKGAIDLAYCDTLYRDLKKGLEGLVLESLLHLIYLTTPYDLAAQSEPDWMVYFKQFGQLSPTEQNVAALLGVSESFIGKKAAGQAVRKKVDKNVVNRLYLSFVLYSLLKETNVWSVSEKFNLPRGYIQNLLMGAASFSSCVLHFCEELEEFWVYKALLVELTKKLTYCVKAELIPLMEVTGVLEGRAKQLYNAGYRSIMHLANANPEVLVKTIDHLSRRQARQIVSSAKMLLHEKAEALQGEAEELLRLPADLPGLGGPSSERAGSHAGDVTLS", "length": 1069 }, "evidence": [ { "id": "RGD:1560216", "url": "https://alliancegenome.org/gene/RGD:1560216#orthology", "database": "AGR" }, { "id": "HGNC:18536", "url": "https://alliancegenome.org/gene/HGNC:18536#orthology", "database": "AGR" }, { "id": "MGI:2176740", "url": "https://alliancegenome.org/gene/MGI:2176740#orthology", "database": "AGR" }, { "id": "FB:FBgn0002899", "url": "https://alliancegenome.org/gene/FB:FBgn0002899#orthology", "database": "AGR" }, { "id": "Q9VSE2", "url": "https://omabrowser.org/oma/group/Q9VSE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TDG4-1", "protein_name": "Helicase POLQ-like", "gene_name": "HELQ", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDECGSRIRRRVSLPKRNRPSLGCIFGAPTAAELVPGDEGKEEEEMVAENRRRKTAGVLPVEVQPLLLSDSPECLVLGGGDTNPDLLRHMPTDRGVGDQPNDSEVDMFGDYDSFTENSFIAQVDDLEQKYMQLPEHKKHATDFATENLCSESIKNKLSITTIGNLTELQTDKHTENQSGYEGVTIEPGADLLYDVPSSQAIYFENLQNSSNDLGDHSMKERDWKSSSHNTVNEELPHNCIEQPQQNDESSSKVRTSSDMNRRKSIKDHLKNAMTGNAKAQTPIFSRSKQLKDTLLSEEINVAKKTVESSSNDLGPFYSLPSKVRDLYAQFKGIEKLYEWQHTCLTLNSVQERKNLIYSLPTSGGKTLVAEILMLQELLCCRKDVLMILPYVAIVQEKISGLSSFGIELGFFVEEYAGSKGRFPPTKRREKKSLYIATIEKGHSLVNSLIETGRIDSLGLVVVDELHMIGEGSRGATLEMTLAKILYTSKTTQIIGMSATLNNVEDLQKFLQAEYYTSQFRPVELKEYLKINDTIYEVDSKAENGMTFSRLLNYKYSDTLKKMDPDHLVALVTEVIPNYSCLVFCPSKKNCENVAEMICKFLSKEYLKHKEKEKCEVIKNLKNIGNGNLCPVLKRTIPFGVAYHHSGLTSDERKLLEEAYSTGVLCLFTCTSTLAAGVNLPARRVILRAPYVAKEFLKRNQYKQMIGRAGRAGIDTIGESILILQEKDKQQVLELITKPLENCYSHLVQEFTKGIQTLFLSLIGLKIATNLDDIYHFMNGTFFGVQQKVLLKEKSLWEITVESLRYLTEKGLLQKDTIYKSEEEVQYNFHITKLGRASFKGTIDLAYCDILYRDLKKGLEGLVLESLLHLIYLTTPYDLVSQCNPDWMIYFRQFSQLSPAEQNVAAILGVSESFIGKKASGQAIGKKVDKNVVNRLYLSFVLYTLLKETNIWTVSEKFNMPRGYIQNLLTGTASFSSCVLHFCEELEEFWVYRALLVELTKKLTYCVKAELIPLMEVTGVLEGRAKQLYSAGYKSLMHLANANPEVLVRTIDHLSRRQAKQIVSSAKMLLHEKAEALQEEVEELLRLPSDFPGAVASSTDKA", "length": 1101 }, "evidence": [ { "id": "RGD:1560216", "url": "https://alliancegenome.org/gene/RGD:1560216#orthology", "database": "AGR" }, { "id": "HGNC:18536", "url": "https://alliancegenome.org/gene/HGNC:18536#orthology", "database": "AGR" }, { "id": "MGI:2176740", "url": "https://alliancegenome.org/gene/MGI:2176740#orthology", "database": "AGR" }, { "id": "FB:FBgn0002899", "url": "https://alliancegenome.org/gene/FB:FBgn0002899#orthology", "database": "AGR" }, { "id": "Q9VSE2", "url": "https://omabrowser.org/oma/group/Q9VSE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "single-stranded 3'-5' DNA helicase activity", "id": "GO:1990518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990518", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE2", "url": "https://www.uniprot.org/uniprotkb/Q9VSE2" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE2", "url": "https://www.uniprot.org/uniprotkb/Q9VSE2" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE2", "url": "https://www.uniprot.org/uniprotkb/Q9VSE2" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE2", "url": "https://www.uniprot.org/uniprotkb/Q9VSE2" } ], "pmid": "" }, { "name": "single-stranded DNA helicase activity", "id": "GO:0017116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017116", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE2", "url": "https://www.uniprot.org/uniprotkb/Q9VSE2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 10, "go_terms": [ { "name": "polarity specification of anterior/posterior axis", "id": "GO:0009949", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009949", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE2", "url": "https://www.uniprot.org/uniprotkb/Q9VSE2" } ], "pmid": "" }, { "name": "female meiosis chromosome segregation", "id": "GO:0016321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016321", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE2", "url": "https://www.uniprot.org/uniprotkb/Q9VSE2" } ], "pmid": "" }, { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE2", "url": "https://www.uniprot.org/uniprotkb/Q9VSE2" } ], "pmid": "" }, { "name": "oogenesis", "id": "GO:0048477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048477", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE2", "url": "https://www.uniprot.org/uniprotkb/Q9VSE2" } ], "pmid": "" }, { "name": "DNA double-strand break processing involved in repair via single-strand annealing", "id": "GO:0010792", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010792", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE2", "url": "https://www.uniprot.org/uniprotkb/Q9VSE2" } ], "pmid": "" }, { "name": "intracellular mRNA localization", "id": "GO:0008298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008298", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE2", "url": "https://www.uniprot.org/uniprotkb/Q9VSE2" } ], "pmid": "" }, { "name": "double-strand break repair via synthesis-dependent strand annealing", "id": "GO:0045003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045003", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE2", "url": "https://www.uniprot.org/uniprotkb/Q9VSE2" } ], "pmid": "" }, { "name": "germarium-derived oocyte fate determination", "id": "GO:0007294", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007294", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE2", "url": "https://www.uniprot.org/uniprotkb/Q9VSE2" } ], "pmid": "" }, { "name": "polarity specification of dorsal/ventral axis", "id": "GO:0009951", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009951", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE2", "url": "https://www.uniprot.org/uniprotkb/Q9VSE2" } ], "pmid": "" }, { "name": "oocyte karyosome formation", "id": "GO:0030717", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030717", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE2", "url": "https://www.uniprot.org/uniprotkb/Q9VSE2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE2", "url": "https://www.uniprot.org/uniprotkb/Q9VSE2" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE2", "url": "https://www.uniprot.org/uniprotkb/Q9VSE2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 211, "end_pos": 213, "annotation": "n_glycosylation_sequon" }, { "start_pos": 430, "end_pos": 432, "annotation": "n_glycosylation_sequon" }, { "start_pos": 485, "end_pos": 487, "annotation": "n_glycosylation_sequon" }, { "start_pos": 709, "end_pos": 711, "annotation": "n_glycosylation_sequon" }, { "start_pos": 753, "end_pos": 755, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O46072-1", "P23128-1", "P26802-1", "Q02748-1", "Q26454-1", "Q9VD51-1", "Q9VNP5-1", "Q9W3Y5-1", "Q7KN62-1", "Q9VF26-1", "Q9VL52-1", "Q07886-1", "Q23976-1", "Q27268-1", "Q9V3C0-1", "Q9VHP0-1", "Q9VHU1-1", "P49735-1", "Q9V461-1", "Q9VGW6-1", "P19109-1", "P29844-1", "Q9VDY1-1", "O61305-2", "Q7K3M5-1", "P09052-1", "A1Z9L3-1", "Q9VN03-1", "Q9VHS8-1", "Q9VUV9-1", "Q9XYU0-1", "Q9XYU1-1", "Q9VIF6-1", "Q9VVK8-1", "Q9VRI0-1", "Q9VJ74-1", "Q9VTC1-1", "Q9VX34-1", "Q9VXW2-1", "Q9W3M7-1", "Q9V3K3-1", "Q9VH07-1", "Q9V3C4-1", "P46461-1", "P54351-1", "Q86B47-1", "Q9I7M8-1", "P24785-1", "A8DZ26-1", "Q9VQN8-1", "Q9VNV3-1", "Q8IRL9-1", "P10987-1", "P10981-1", "P20480-1", "Q9VL25-1", "P53501-1", "Q8ING5-1", "Q6J5K9-1", "P02572-1", "P83967-1", "P02574-1", "Q9VL76-1", "Q9VDA0-1", "Q9W4W2-1", "Q9VIZ3-1", "Q9VY54-1", "Q9VR29-1", "Q7JYV7-1", "Q9VGI8-1", "Q02870-1", "Q9W252-1", "Q9W484-1", "O16102-1", "Q9VSE2-1", "Q9VSE6-1", "Q7KVP9-1", "Q7KU24-1", "Q7KSN8-1", "O97159-1", "Q9VZ55-1", "Q9GQN5-1", "Q9VCH8-1", "Q9XZS9-1", "Q9VQR3-1", "Q9VTL5-1", "Q9VYS3-1", "Q9VL72-1", "Q9VF30-1", "O76460-1", "P25439-1", "Q9VF56-1" ], "evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A1Z9L3", "gene_name": "pea", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A1Z9L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1Z9L3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A1Z9L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1Z9L3" } ] } ] }, { "uniprot_ac": "A8DZ26", "gene_name": "anne", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A8DZ26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8DZ26" } ] } ] }, { "uniprot_ac": "O16102", "gene_name": "Chd3", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "O16102", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O16102" } ] } ] }, { "uniprot_ac": "O46072", "gene_name": "kz", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "O46072", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O46072" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "O46072", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O46072" } ] } ] }, { "uniprot_ac": "O61305", "gene_name": "Dbp80", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "O61305", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O61305" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "O61305", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O61305" } ] } ] }, { "uniprot_ac": "O76460", "gene_name": "okr", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "O76460", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O76460" } ] } ] }, { "uniprot_ac": "O97159", "gene_name": 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"id": "IPR004589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004589", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011545", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011545", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG7487", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG7487", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YLMICKV", "url": "https://omabrowser.org/oma/group/YLMICKV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VSE6", "url": "https://www.orthodb.org/?gene=Q9VSE6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13710", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13710", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13710:SF108", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13710:SF108", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00270", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00270", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11719", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11719", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_652607", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_652607", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q9VSE6", "url": "https://www.uniprot.org/uniprotkb/Q9VSE6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VSE6-1", "url": "https://www.uniprot.org/uniprotkb/Q9VSE6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDDSVFKLKYQKYKLRVKVWEKDFKKKNGRVPSKYDIRDASQEIRDSYKMYYKLKTSFLEETLNDVLSEDGYDILEMSQASDFGVSMLDQDVSLNEGPQLPLDISALVGPQSSGNLEEIPQSVEGSFSNLIDLPNRQVLTNLVNRDENHVIRKFEAVEELPINQNAWGLNVSKKPPAPPQPVEASKSAPGHGKQPKAGASLKPSLSAKLFQSSRGFAKRNPRKPLSRCVSSSSSTTSLSSVPTDHHEELLDFETILIRKAQEYKEKQQAIANNPMLASEHSKESIKTLVDDGWLRRNTKENTLDEEVPFAEANNNSGTSKKTNFGLANLDLSKLKPTVKEEKVLQAKPDQMAIIQELQTDMNSSMNQKPDHLNHTPPASSQKSVAPKNKPPPSEQETDSDSDSVVAESEEEQEPQEYRQLSKRRKIVSTASGKVEVAAPVEIPNKVEPETETFAQENPDFSADEDQDATYVPENKKKDKAKRKQAAGKQKTTKPKAEPKPKTEKKAKVKAEKKPKAEKKPRNSKKAIAVEPAPDPEEDERQPLNPEDLKYVLALEAGDITSVPRINVQDLEEADATAQRYIRTFAAGPNPGLSEGSNIRVDEKRAAARKKLEERIAAGKLNENFVTINIQKKKFVRGKKSVNFSKYKKQQWRHKKRVAALSGPDMDMGGCDGGVLTCFQCGGVGHFAQQCKVKGDSLLPLSAQLEEDPSPFPTLAEAQEMASQGAVVAHSRNISRLPQAANAAILQGDELNESEEDDQESSGDEEVQQHPDPNWSSDEMDVDFEALDAAVEASLSQPVSQEKAASPIKTYVGHKIPEEFLKQAGLDTTASSSNRSQHGGVKPLYDLLPDGSVQDTTPEVLEALHMFGHTNFRKGQDRAIMRTLSGLSSLVTLSTGSGKSLCYQLPAYLYSRKVGAITLVISPLVSLMEDQVTGVPHFLRAHCLHTNQTAPQRMKIQQMIANGEIDILLVSPEAVVAGERATGFGAILRQLPPIAFACIDEAHCVSQWSHNFRPSYLMICKVLRKNLGVRTVLGLTATATLPTRVSIINHLGISDGERGIISDIPLPDNLVLSVSKDENRDAALLQLLNSERFEPCQSIIIYCTRRDECERIAGFIRTCVQDRREPTQDQTKKRKRVNWQAEPYHAGMPASRRRTVQKAFMSNELRIVVATIAFGMGINKPDIRAVIHYNMPRNFESYVQEIGRAGRDGLPSHCHLFLDAKGGDQSELRRHVYSNSIDRHVIRKLLQKIFVPCSCDKEASKRTALPIPLEGDGPRVHMCPGHEIGFSVEKTVEMLDIPAENISTLLCYMELDPRWCISVLSSAYVMAKVISYGGPKYLKHAAKECPPLAMAIALQIRDKTFKEDSNIIEFSVTDIAAGIGWNSGVVKYQLKDLEWVKVNGYPKRSPITVSFYDLGFRIKVPGDFTESEIDNALDTLYTRSVKQERTQLIQLQYVAHGLAAVAYSSCGQCCNADFPQDRGEQLKAIVRNYFANDYPQDLELEIEPSNVPDENIIDDVHALINMYPDNTFTGRNIARIFHGIMSPNYPAVIWGRCKFWRAHVKVDFNRILHLANMAIIKRRT", "length": 1579, "header": "tr|Q9VSE6-1|Q9VSE6_DROME Isoform 1 of ATP-dependent DNA helicase Q4 OS=Drosophila melanogaster OX=7227 GN=RecQ4 PE=1 SV=1 CANONICAL=Q9VSE6-1" }, "isoforms": [ { "isoform_ac": "Q9VSE6-1", "url": "https://www.uniprot.org/uniprotkb/Q9VSE6/entry#Q9VSE6-1", "sequence": { "sequence": "MDDSVFKLKYQKYKLRVKVWEKDFKKKNGRVPSKYDIRDASQEIRDSYKMYYKLKTSFLEETLNDVLSEDGYDILEMSQASDFGVSMLDQDVSLNEGPQLPLDISALVGPQSSGNLEEIPQSVEGSFSNLIDLPNRQVLTNLVNRDENHVIRKFEAVEELPINQNAWGLNVSKKPPAPPQPVEASKSAPGHGKQPKAGASLKPSLSAKLFQSSRGFAKRNPRKPLSRCVSSSSSTTSLSSVPTDHHEELLDFETILIRKAQEYKEKQQAIANNPMLASEHSKESIKTLVDDGWLRRNTKENTLDEEVPFAEANNNSGTSKKTNFGLANLDLSKLKPTVKEEKVLQAKPDQMAIIQELQTDMNSSMNQKPDHLNHTPPASSQKSVAPKNKPPPSEQETDSDSDSVVAESEEEQEPQEYRQLSKRRKIVSTASGKVEVAAPVEIPNKVEPETETFAQENPDFSADEDQDATYVPENKKKDKAKRKQAAGKQKTTKPKAEPKPKTEKKAKVKAEKKPKAEKKPRNSKKAIAVEPAPDPEEDERQPLNPEDLKYVLALEAGDITSVPRINVQDLEEADATAQRYIRTFAAGPNPGLSEGSNIRVDEKRAAARKKLEERIAAGKLNENFVTINIQKKKFVRGKKSVNFSKYKKQQWRHKKRVAALSGPDMDMGGCDGGVLTCFQCGGVGHFAQQCKVKGDSLLPLSAQLEEDPSPFPTLAEAQEMASQGAVVAHSRNISRLPQAANAAILQGDELNESEEDDQESSGDEEVQQHPDPNWSSDEMDVDFEALDAAVEASLSQPVSQEKAASPIKTYVGHKIPEEFLKQAGLDTTASSSNRSQHGGVKPLYDLLPDGSVQDTTPEVLEALHMFGHTNFRKGQDRAIMRTLSGLSSLVTLSTGSGKSLCYQLPAYLYSRKVGAITLVISPLVSLMEDQVTGVPHFLRAHCLHTNQTAPQRMKIQQMIANGEIDILLVSPEAVVAGERATGFGAILRQLPPIAFACIDEAHCVSQWSHNFRPSYLMICKVLRKNLGVRTVLGLTATATLPTRVSIINHLGISDGERGIISDIPLPDNLVLSVSKDENRDAALLQLLNSERFEPCQSIIIYCTRRDECERIAGFIRTCVQDRREPTQDQTKKRKRVNWQAEPYHAGMPASRRRTVQKAFMSNELRIVVATIAFGMGINKPDIRAVIHYNMPRNFESYVQEIGRAGRDGLPSHCHLFLDAKGGDQSELRRHVYSNSIDRHVIRKLLQKIFVPCSCDKEASKRTALPIPLEGDGPRVHMCPGHEIGFSVEKTVEMLDIPAENISTLLCYMELDPRWCISVLSSAYVMAKVISYGGPKYLKHAAKECPPLAMAIALQIRDKTFKEDSNIIEFSVTDIAAGIGWNSGVVKYQLKDLEWVKVNGYPKRSPITVSFYDLGFRIKVPGDFTESEIDNALDTLYTRSVKQERTQLIQLQYVAHGLAAVAYSSCGQCCNADFPQDRGEQLKAIVRNYFANDYPQDLELEIEPSNVPDENIIDDVHALINMYPDNTFTGRNIARIFHGIMSPNYPAVIWGRCKFWRAHVKVDFNRILHLANMAIIKRRT", "length": 1579, "header": "tr|Q9VSE6-1|Q9VSE6_DROME Isoform 1 of ATP-dependent DNA helicase Q4 OS=Drosophila melanogaster OX=7227 GN=RecQ4 PE=1 SV=1 CANONICAL=Q9VSE6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE6", "url": "https://www.uniprot.org/uniprotkb/Q9VSE6" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE6", "url": "https://www.uniprot.org/uniprotkb/Q9VSE6" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE6", "url": "https://www.uniprot.org/uniprotkb/Q9VSE6" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE6", "url": "https://www.uniprot.org/uniprotkb/Q9VSE6" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE6", "url": "https://www.uniprot.org/uniprotkb/Q9VSE6" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE6", "url": "https://www.uniprot.org/uniprotkb/Q9VSE6" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE6", "url": "https://www.uniprot.org/uniprotkb/Q9VSE6" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE6", "url": "https://www.uniprot.org/uniprotkb/Q9VSE6" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE6", "url": "https://www.uniprot.org/uniprotkb/Q9VSE6" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE6", "url": "https://www.uniprot.org/uniprotkb/Q9VSE6" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE6", "url": "https://www.uniprot.org/uniprotkb/Q9VSE6" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG7487", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG7487", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0L7P8-1", "protein_name": "DNA 3'-5' helicase", "gene_name": "Recql4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MERLATVRARLQDWERAFVRLHGRRPAKEDVEAAPEETRALYREYRNLKQAVSQADDGHRVQKQSLAKAAEEEQEPSCWGSHLNRAATQNTQSIPKQSPLSSIQDYGKRLKANLKNTLQGGPTLSRKLQHQKRSLSIVPTSRPPGPRTESPCPEQANDALPQVPVPQPRQGQLQKLQSSLSLRLSSLDPGWLERCQNRVSDPLEVPGACGLDLSAKESQPQMSGKVNVISPDILSEVSSQSPQALAQQPAQVLSQIPKSSNSKDRKRKRNEKGEDFAQAQPSSQAGPLSEGAGATAHGQGPPGEPTQVTVPQHRCSSNQARTENAKSAAHLPMSPRPASLDRGNYVRLNMKTKCFVRVGASRGRLLRKQVWKQKWKKKQEWFGKSGPRATVKDTCFRCGQFGHWASQCSQPGSTLTIQPKGDRNDKHPISTLGGVAQKTGTTSCNHSGEETEPAGPVLPVPHCPTPVLPLYPPGPLGQVADTPAEVFQVLEQLGHHTFRPGQERAVMRILSGISTLLVLPTGAGKSLCYQLPALLYAKRSPCLTLVVSPLLSLMDDQVSDLPSCLKAACLHSGMTKKQRESVLKKVRMAHGWGGGHPSTQSLILSSLQVRAAQVHVLIVSPEALVGCGAKGPANLPPAAQLPPVAFACIDEVHCLSQWSHNFRPCYLRVCKVLREHMGVRCFLGLTATATRSTARDVAQHLGIAEELEVSGSASIPANLHLSVSMDRDSDQALVTLLQGDRFRTLDSIIIYCARRKDTERVAALLRTCLSTVRDSKPRGRGPETLAEAYHAGMCSQERKRVQQAFMQGHLRMVVATVAFGMGLDRPDVRAVLHLGLPPSFESYVQAIGRAGRDGKPAHCHLFLHPQGEDLWELSRHVHADSTDFLAVKKLVQRVFPACSCAQRPMSPLEEVKEHSGQQTYPVLGLACRGHKRALPVQSTVLALDMKEEAIETLLCYLELHPRHWLELLPYTYAHCHLRCPGGSAQLQALVHRCPPLAACWAKWPPKDTSQGSSALEFDVVELADSMGWELASVRQALHQLKWDPEPKKGAPQGTGVLVEFSELAFHLHSRGDLTDEEKDQICDFLYSRVQAREHKALAHLHQMSKAFQSVAFPSCGPCLEQSDEGHSNRVKTLVSYYFEEEEEEEEEETMKDTQDPKPGQTQLQDWEDQVRRDVHQLLSLRPEEKFSGRAVARIFHGIASPCYPAQVFGQDRRFWRKYLHLDFHALMHLATEELLLRGR", "length": 1239 }, "evidence": [ { "id": "RGD:1307732", "url": "https://alliancegenome.org/gene/RGD:1307732#orthology", "database": "AGR" }, { "id": "HGNC:9949", "url": "https://alliancegenome.org/gene/HGNC:9949#orthology", "database": "AGR" }, { "id": "MGI:1931028", "url": "https://alliancegenome.org/gene/MGI:1931028#orthology", "database": "AGR" }, { "id": "FB:FBgn0040290", "url": "https://alliancegenome.org/gene/FB:FBgn0040290#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7F2M7-1", "protein_name": "ATP-dependent DNA helicase Q4", "gene_name": "recql4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDRYNDVKILLKKWEQSFFQTNNRKPNKDDIDKAPEETRQLYKEYRSLKVAKERNDAVKESQTKPPESQSSTDGSGCWGSHLNRKNLPVALPKLSSDDKETLKASAQYFGMKLKNNLGGLTKERSFSLKKAATPRRTPQKLIKDTVDSNAAATDVESHTPKPANTCPDPSAAPVQAAKMDFEDDPSDPFPSITPSKPCSTVVGSAQKSVERVQFLRQSITRRFSSVDSGWLARCQVFDEVEEPQKPVAGNSELAKDEKSFLQPAVGSKSGSPGTHGERVSHKNSPNEGQTFSNTLLGRKKSSLPEEEAQIDLVTSSVRNNVVLNAISGSPGTHGERVSLKSSPKLRVDDENLSEEPEFTPNTKQRKTKARKDQDSGAKTKGRKRQREADNGDDMDESEEKEGGVKKRRKTKKGETAGEDQPKKRGKKKGKVEEDDDDGSSENKKPQKRAMPQENLLGEVDEEEARAAAYAMKNTVRVRPTKNTDGNFVKINLKKKSHVKGFALRGAALRKQMYMQKFQLKGERFGGGFGRGRGRFGGFNRQGDTCYKCGGTGHWAQDCRGKVPVNTSAEQQETPVEEEEFELPTLEEVARATGTLRSEPIVAPPSADGDSSEKEEQGAEILLNIIRPDYERPAPPPPMEPLYKLKDDGKVQDVPPEVYEALRDFGYKSFRPGQEAAIMRILSGLSTLVVLSTGMGKSLCYQLPAYLYAQRSKSITLVVSPLVSLMDDQLSGLPPKLKAACIHSNMSAKQREAAIEKVKAGQVHVLLLSPEALVGGGHSGSGCLPPADQLPPVAFACIDEAHCVSEWSHNFRPCYLRLCKVLRDRLGVRCLLGLTATATLSTALDIARHLDISDEDGIAVRSAAVPHNLQLSVSMDRDKDQALVSLLKGERFGALDSVIVYCTRREETSRIAALLRTCLQGVMLRESSKHTALQEDDDNPVGKKKKALARKKIRKPLKWIAEAYHAGLSASERRRVQNNFMCGELRVVVATVAFGMGLDKSDVRGIIHYNMPKSFESYVQEIGRAGRDGHPAHCHLFLDPEGGDLHELRRHIYADTVDYYTVKKLVQKVFPPCKCRQIQQKQQDLAQAAEVSDSELLEMELCDDSDPHQNEIPTLTHQQTPQTHTPEETEERPQLSDECVQRFCHTHERAIPMQETVEALDITEESLETLLCYLELHPQQWVELLHPTLSVCKLQCYGGPQQLRKIAKLCAPVAVVLARRRMAGERVQSCDALEFDVVELADTMGWQLPLVKRGLRQLQWGSDTGSYGGTGRSGVHVEFSALSFYFRSYGDLTADELDAVCAFLHGRVKTQENTQLYQLKTCFRAFRSVAYRNCSLCLDDLEESRSQALKDLLSDYFDKRRNLELSKQCLEDEHDEEEELNKCKMRDWETQICADIRAFLCSRSDEKFSGRAVARIFHGIGSPCYPAQVYGRDRRFWRKYIQFDFNEIIRLATQEIIRTR", "length": 1459 }, "evidence": [ { "id": "HGNC:9949", "url": "https://alliancegenome.org/gene/HGNC:9949#orthology", "database": "AGR" }, { "id": "MGI:1931028", "url": "https://alliancegenome.org/gene/MGI:1931028#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O94761-1", "protein_name": "ATP-dependent DNA helicase Q4", "gene_name": "RECQL4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MERLRDVRERLQAWERAFRRQRGRRPSQDDVEAAPEETRALYREYRTLKRTTGQAGGGLRSSESLPAAAEEAPEPRCWGPHLNRAATKSPQSTPGRSRQGSVPDYGQRLKANLKGTLQAGPALGRRPWPLGRASSKASTPKPPGTGPVPSFAEKVSDEPPQLPEPQPRPGRLQHLQASLSQRLGSLDPGWLQRCHSEVPDFLGAPKACRPDLGSEESQLLIPGESAVLGPGAGSQGPEASAFQEVSIRVGSPQPSSSGGEKRRWNEEPWESPAQVQQESSQAGPPSEGAGAVAVEEDPPGEPVQAQPPQPCSSPSNPRYHGLSPSSQARAGKAEGTAPLHIFPRLARHDRGNYVRLNMKQKHYVRGRALRSRLLRKQAWKQKWRKKGECFGGGGATVTTKESCFLNEQFDHWAAQCPRPASEEDTDAVGPEPLVPSPQPVPEVPSLDPTVLPLYSLGPSGQLAETPAEVFQALEQLGHQAFRPGQERAVMRILSGISTLLVLPTGAGKSLCYQLPALLYSRRSPCLTLVVSPLLSLMDDQVSGLPPCLKAACIHSGMTRKQRESVLQKIRAAQVHVLMLTPEALVGAGGLPPAAQLPPVAFACIDEAHCLSQWSHNFRPCYLRVCKVLRERMGVHCFLGLTATATRRTASDVAQHLAVAEEPDLHGPAPVPTNLHLSVSMDRDTDQALLTLLQGKRFQNLDSIIIYCNRREDTERIAALLRTCLHAAWVPGSGGRAPKTTAEAYHAGMCSRERRRVQRAFMQGQLRVVVATVAFGMGLDRPDVRAVLHLGLPPSFESYVQAVGRAGRDGQPAHCHLFLQPQGEDLRELRRHVHADSTDFLAVKRLVQRVFPACTCTCTRPPSEQEGAVGGERPVPKYPPQEAEQLSHQAAPGPRRVCMGHERALPIQLTVQALDMPEEAIETLLCYLELHPHHWLELLATTYTHCRLNCPGGPAQLQALAHRCPPLAVCLAQQLPEDPGQGSSSVEFDMVKLVDSMGWELASVRRALCQLQWDHEPRTGVRRGTGVLVEFSELAFHLRSPGDLTAEEKDQICDFLYGRVQARERQALARLRRTFQAFHSVAFPSCGPCLEQQDEERSTRLKDLLGRYFEEEEGQEPGGMEDAQGPEPGQARLQDWEDQVRCDIRQFLSLRPEEKFSSRAVARIFHGIGSPCYPAQVYGQDRRFWRKYLHLSFHALVGLATEELLQVAR", "length": 1208 }, "evidence": [ { "id": "RGD:1307732", "url": "https://alliancegenome.org/gene/RGD:1307732#orthology", "database": "AGR" }, { "id": "HGNC:9949", "url": "https://alliancegenome.org/gene/HGNC:9949#orthology", "database": "AGR" }, { "id": "MGI:1931028", "url": "https://alliancegenome.org/gene/MGI:1931028#orthology", "database": "AGR" }, { "id": "FB:FBgn0040290", "url": "https://alliancegenome.org/gene/FB:FBgn0040290#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q75NR7-1", "protein_name": "ATP-dependent DNA helicase Q4", "gene_name": "Recql4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERLATVRARLQEWERAFARLHGRRPAKGDVEAAPEETRALYREYRNLKQAVRQADDRHRVLEQSLAEAAEEAQEPSCWGPHLSRAATQNTQSMPKQSLLSSVQDYGKRLKANLKNTTQTGPTQSRKLQLQKRSLSTVPAPRPPGSKTESPCPDEADDALPRVPEPRPRLGQLQQLRSSLSRRLTSLDPGWLERCHNRVSDLLEVPGACGLDLSAEESQPQMSGKVNIADPDIQSEVSVQSPEAIAQQPAQVLSQSPKSINSKGRKRKWNEKGEDFAQDQPSSGAGPLSEGARATVHGQDPPGEPTQVNVPQPCNSSNQARTEKAKGTTHLHASPRPASLDRGNYIRLNMKNKRFVRVGANRGRLLRKQVWKQKWKKKQAAFGGSGPRATDKDTCFRCGQFGHWASQCSQPGPTLTVQEEGDRDDKQPISTLEEVAQRTGTASCHHSGEETQPAAPELQVPHCPTPMSPLYPPGPLGQVAETPAEVFQALERLGYRAFRPGQERAIMRILSGISTLLVLPTGAGKSLCYQLPALLYAQRSPCLTLVVSPLLSLMDDQVSDLPSCLKAACLHSGMTKKQRESVLKKVRAAQVHVLIVSPEALVGCGARGPGSLPQAAQLPPIAFACIDEVHCLSQWSHNFRPCYLRVCKVLREHMGVRCFLGLTATATRSTARDVAQHLGIAGEFELSGSANIPANLHLSVSMDRDSDQALVTLLQGDRFRTLDSVIIYCTRERIQNGWLALLRTCLSMVGDSRPRGCGPEAIAEAYHAGMSSQERRRVQQAFMRGHLRMVVATVAFGMGLDRPDVRAVLHLGLPPSFESYVQAIGRAGRDGKPAHCHLFMHPQGEDLWELRRHAHADSTDFLAVKRLVQRVFPPCTCSQRPVSKSSPEEVKEHSGQQTYPVLGQACLGHERALPVQSTVQALDMTEEAIETLLCYLELHPRHWLELLPWTYAQCHLHCLGGSAQLQALAHRCPPLAACQAKWPPKDTSQGRSSLEFGVVELADSMGWKLASVRQALHQLKWDPEPKKGAAQGTGVLVKFSELAFHLHSRGDLTDEEKDQICDFLYNRVQAREHKALAHLHQMSKAFRSVAFPSCGPCLEQSNEEHSNQVKTLVSYYFEEEEEEEETMTDTQGPKPGQTQLQDWEDQIRRDVRQLLSLRPEERFSGRAVARIFHGIASPCYPAQVYGLDRRFWRKYLHLDFHALMHLATEELLLRGR", "length": 1216 }, "evidence": [ { "id": "RGD:1307732", "url": "https://alliancegenome.org/gene/RGD:1307732#orthology", "database": "AGR" }, { "id": "HGNC:9949", "url": "https://alliancegenome.org/gene/HGNC:9949#orthology", "database": "AGR" }, { "id": "MGI:1931028", "url": "https://alliancegenome.org/gene/MGI:1931028#orthology", "database": "AGR" }, { "id": "FB:FBgn0040290", "url": "https://alliancegenome.org/gene/FB:FBgn0040290#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 10, "go_terms": [ { "name": "3'-5' DNA helicase activity", "id": "GO:0043138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043138", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE6", "url": "https://www.uniprot.org/uniprotkb/Q9VSE6" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE6", "url": "https://www.uniprot.org/uniprotkb/Q9VSE6" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE6", "url": "https://www.uniprot.org/uniprotkb/Q9VSE6" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE6", "url": "https://www.uniprot.org/uniprotkb/Q9VSE6" } ], "pmid": "" }, { "name": "single-stranded DNA binding", "id": "GO:0003697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE6", "url": "https://www.uniprot.org/uniprotkb/Q9VSE6" } ], "pmid": "" }, { "name": "helicase activity", "id": "GO:0004386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004386", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE6", "url": "https://www.uniprot.org/uniprotkb/Q9VSE6" } ], "pmid": "" }, { "name": "ATP-dependent DNA/DNA annealing activity", "id": "GO:0036310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036310", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE6", "url": "https://www.uniprot.org/uniprotkb/Q9VSE6" } ], "pmid": "" }, { "name": "DNA helicase activity", "id": "GO:0003678", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003678", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE6", "url": "https://www.uniprot.org/uniprotkb/Q9VSE6" } ], "pmid": "" }, { "name": "ATP-dependent activity, acting on DNA", "id": "GO:0008094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008094", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE6", "url": "https://www.uniprot.org/uniprotkb/Q9VSE6" } ], "pmid": "" }, { "name": "four-way junction helicase activity", "id": "GO:0009378", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009378", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE6", "url": "https://www.uniprot.org/uniprotkb/Q9VSE6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE6", "url": "https://www.uniprot.org/uniprotkb/Q9VSE6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE6", "url": "https://www.uniprot.org/uniprotkb/Q9VSE6" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE6", "url": "https://www.uniprot.org/uniprotkb/Q9VSE6" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE6", "url": "https://www.uniprot.org/uniprotkb/Q9VSE6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE6", "url": "https://www.uniprot.org/uniprotkb/Q9VSE6" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE6", "url": "https://www.uniprot.org/uniprotkb/Q9VSE6" } ], "pmid": "" }, { "name": "base-excision repair", "id": "GO:0006284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006284", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE6", "url": "https://www.uniprot.org/uniprotkb/Q9VSE6" } ], "pmid": "" }, { "name": "DNA replication", "id": "GO:0006260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006260", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE6", "url": "https://www.uniprot.org/uniprotkb/Q9VSE6" } ], "pmid": "" }, { "name": "double-strand break repair", "id": "GO:0006302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE6", "url": "https://www.uniprot.org/uniprotkb/Q9VSE6" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE6", "url": "https://www.uniprot.org/uniprotkb/Q9VSE6" } ], "pmid": "" }, { "name": "chromosome organization", "id": "GO:0051276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051276", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE6", "url": "https://www.uniprot.org/uniprotkb/Q9VSE6" } ], "pmid": "" }, { "name": "larval development", "id": "GO:0002164", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002164", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE6", "url": "https://www.uniprot.org/uniprotkb/Q9VSE6" } ], "pmid": "" }, { "name": "eggshell chorion gene amplification", "id": "GO:0007307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007307", "evidence": [ { "database": "UniProtKB", "id": "Q9VSE6", "url": "https://www.uniprot.org/uniprotkb/Q9VSE6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1300, "end_pos": 1302, "annotation": "n_glycosylation_sequon" }, { "start_pos": 170, "end_pos": 172, "annotation": "n_glycosylation_sequon" }, { "start_pos": 314, "end_pos": 316, "annotation": "n_glycosylation_sequon" }, { "start_pos": 362, "end_pos": 364, "annotation": "n_glycosylation_sequon" }, { "start_pos": 373, "end_pos": 375, "annotation": "n_glycosylation_sequon" }, { "start_pos": 642, "end_pos": 644, "annotation": "n_glycosylation_sequon" }, { "start_pos": 732, "end_pos": 734, "annotation": "n_glycosylation_sequon" }, { "start_pos": 751, "end_pos": 753, "annotation": "n_glycosylation_sequon" }, { "start_pos": 773, "end_pos": 775, "annotation": "n_glycosylation_sequon" }, { "start_pos": 833, "end_pos": 835, "annotation": "n_glycosylation_sequon" }, { "start_pos": 946, "end_pos": 948, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O46072-1", "P23128-1", "P26802-1", "Q02748-1", "Q26454-1", "Q9VD51-1", "Q9VNP5-1", "Q9W3Y5-1", "Q7KN62-1", "Q9VF26-1", "Q9VL52-1", "Q07886-1", "Q23976-1", "Q27268-1", "Q9V3C0-1", "Q9VHP0-1", "Q9VHU1-1", "P49735-1", "Q9V461-1", "Q9VGW6-1", "P19109-1", "P29844-1", "Q9VDY1-1", "O61305-2", "Q7K3M5-1", "P09052-1", "A1Z9L3-1", "Q9VN03-1", "Q9VHS8-1", "Q9VUV9-1", "Q9XYU0-1", "Q9XYU1-1", "Q9VIF6-1", "Q9VVK8-1", "Q9VRI0-1", "Q9VJ74-1", "Q9VTC1-1", "Q9VX34-1", "Q9VXW2-1", "Q9W3M7-1", "Q9V3K3-1", "Q9VH07-1", 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"evidence": [ { "id": "Q9VIF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VIF6" } ] } ] }, { "uniprot_ac": "Q9VIZ3", "gene_name": "l(2)37Cb", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q9VIZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VIZ3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q9VIZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VIZ3" } ] } ] }, { "uniprot_ac": "Q9VJ74", "gene_name": "Dmel\\CG10333", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q9VJ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJ74" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q9VJ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJ74" } ] } ] }, { "uniprot_ac": "Q9VL25", "gene_name": 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duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "Q9VYS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VYS3" } ] }, { "ec_number": "5.6.2.5", "activity": "n ATP + n H2O + wound RNA = n ADP + n phosphate + unwound RNA.", "evidence": [ { "id": "Q9VYS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VYS3" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "Q9VYS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VYS3" } ] }, { "ec_number": "5.6.2.5", "activity": "", "evidence": [ { "id": "Q9VYS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VYS3" } ] } ] }, { "uniprot_ac": "Q9VZ55", "gene_name": "Dmel\\CG1582", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q9VZ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ55" } ] }, { 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"sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1300, "end_pos": 1302 }, { "start_pos": 170, "end_pos": 172 }, { "start_pos": 314, "end_pos": 316 }, { "start_pos": 362, "end_pos": 364 }, { "start_pos": 373, "end_pos": 375 }, { "start_pos": 642, "end_pos": 644 }, { "start_pos": 732, "end_pos": 734 }, { "start_pos": 751, "end_pos": 753 }, { "start_pos": 773, "end_pos": 775 }, { "start_pos": 833, "end_pos": 835 }, { "start_pos": 946, "end_pos": 948 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"https://www.ncbi.nlm.nih.gov/protein/NP_648189" }, "gene_names": [ { "name": "anon-WO0140519.185", "type": "recommended", "evidence": [ { "id": "Q9VSF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSF5" } ] }, { "name": "CG7366", "type": "synonym", "evidence": [ { "id": "NP_648189", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648189" }, { "id": "Q9VSF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSF5" } ] }, { "name": "Dmel\\CG7366", "type": "synonym", "evidence": [ { "id": "NP_648189", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648189" }, { "id": "Q9VSF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSF5" } ] }, { "name": "Dmel_CG7366", "type": "synonym", "evidence": [ { "id": "Q9VSF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSF5" } ] }, { "name": "anon-WO0140519.185", "type": "synonym", "evidence": [ { "id": "NP_648189", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648189" } ] } ], "protein_names": [ { "name": "DUF4485 domain-containing protein", "type": "recommended", "evidence": [ { "id": "Q9VSF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSF5/entry#names_and_taxonomy" } ] }, { "name": "CG7366-PA", "type": "synonym", "evidence": [ { "id": "NP_648189", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648189" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_648189", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648189" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VSF5", "url": "https://www.uniprot.org/uniprotkb/Q9VSF5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "anon-WO0140519.185", "url": "https://www.uniprot.org/uniprotkb/Q9VSF5", "locus": { "chromosome": "3L", "start_pos": 8201078, "end_pos": 8202417, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0035855", "url": "https://www.ensemblgenomes.org/id/FBgn0035855" } ] } } ], "crossref": [ { "id": "FB:FBgn0035855", "url": "https://alliancegenome.org/gene/FB:FBgn0035855", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0035855", "url": "https://bgee.org/?page=gene&gene_id=FBgn0035855", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0035855", "url": "https://flybase.org/reports/FBgn0035855", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "38918", "url": "https://www.ncbi.nlm.nih.gov/gene/38918", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VSF5", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VSF5*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "dme:Dmel_CG7366", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG7366", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DKFARNC", "url": "https://omabrowser.org/oma/group/DKFARNC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VSF5", "url": "https://www.orthodb.org/?gene=Q9VSF5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "NP_648189", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648189", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VSF5", "url": "https://www.uniprot.org/uniprotkb/Q9VSF5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VSF5-1", "url": "https://www.uniprot.org/uniprotkb/Q9VSF5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTQLSEFALDSHFASELRSLQLYSKEHPVSQDDHDISQRWMQHFQNAKGLDKFARNCMLLMMCEQLRDLGHLSKPFTELKNLSRPMDDLLNEYHGTTTVEEGQMSPVEDIEDSDTNVSNYGSGSSSFSPGVPYPISTPEFESIKRSNQDLLKEIDSLHCRTVEAEKLYLSRSQILEKQIAEKSALAKTKLPQEGIYQSCRAACQLLKKWPGESVRLNFLTTCLEPFLRNDMITSLQISELDLSFENTLNAMVKRACSRRDDNVRMLYDQILCQEKNDLKEKEDKVRRLQESTRLERQRLRALAEDLKRRENFIWRHQAVATLAVAGLSSDDQRSPSSTNLKCDSCLKEMSIRKGPLDPIGRSSKGEKTNDVVDLEKLSDALSDMSIDKW", "length": 389, "header": "tr|Q9VSF5-1|Q9VSF5_DROME Isoform 1 of DUF4485 domain-containing protein OS=Drosophila melanogaster OX=7227 GN=anon-WO0140519.185 PE=4 SV=1 CANONICAL=Q9VSF5-1" }, "isoforms": [ { "isoform_ac": "Q9VSF5-1", "url": "https://www.uniprot.org/uniprotkb/Q9VSF5/entry#Q9VSF5-1", "sequence": { "sequence": "MTQLSEFALDSHFASELRSLQLYSKEHPVSQDDHDISQRWMQHFQNAKGLDKFARNCMLLMMCEQLRDLGHLSKPFTELKNLSRPMDDLLNEYHGTTTVEEGQMSPVEDIEDSDTNVSNYGSGSSSFSPGVPYPISTPEFESIKRSNQDLLKEIDSLHCRTVEAEKLYLSRSQILEKQIAEKSALAKTKLPQEGIYQSCRAACQLLKKWPGESVRLNFLTTCLEPFLRNDMITSLQISELDLSFENTLNAMVKRACSRRDDNVRMLYDQILCQEKNDLKEKEDKVRRLQESTRLERQRLRALAEDLKRRENFIWRHQAVATLAVAGLSSDDQRSPSSTNLKCDSCLKEMSIRKGPLDPIGRSSKGEKTNDVVDLEKLSDALSDMSIDKW", "length": 389, "header": "tr|Q9VSF5-1|Q9VSF5_DROME Isoform 1 of DUF4485 domain-containing protein OS=Drosophila melanogaster OX=7227 GN=anon-WO0140519.185 PE=4 SV=1 CANONICAL=Q9VSF5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VSF5", "url": "https://www.uniprot.org/uniprotkb/Q9VSF5" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VSF5", "url": "https://www.uniprot.org/uniprotkb/Q9VSF5" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VSF5", "url": "https://www.uniprot.org/uniprotkb/Q9VSF5" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VSF5", "url": 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Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VSF5", "url": "https://www.uniprot.org/uniprotkb/Q9VSF5" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VSF5", "url": "https://www.uniprot.org/uniprotkb/Q9VSF5" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi 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The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing." }, "synonyms": [ { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "bronchial hyperreactivity", "description": "" }, { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "chronic obstructive asthma", "description": "" }, { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "chronic obstructive asthma with acute exacerbation", "description": "" }, { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "chronic obstructive asthma with status asthmaticus", "description": "" }, { "id": "MONDO:0010940", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010940", "name": "inherited susceptibility to asthma", "description": "" }, { "id": "MONDO:0010940", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010940", "name": "asthma, nocturnal, susceptibility to", "description": "" }, { "id": "MIM:600807", "resource": "MIM", "url": "https://www.omim.org/entry/600807", "name": "Asthma", "description": "Asthma" } ], "unlinked_id_list": [ "DOID:0080811", "DOID:0080819" ], "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VSL6", "url": "https://www.uniprot.org/uniprotkb/Q9VSL6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "GstO1", "url": "https://www.uniprot.org/uniprotkb/Q9VSL6", "locus": { "chromosome": "3L", "start_pos": 8523742, "end_pos": 8524866, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0035907", "url": "https://www.ensemblgenomes.org/id/FBgn0035907" } ] } } ], "crossref": [ { "id": "FB:FBgn0035907", "url": "https://alliancegenome.org/gene/FB:FBgn0035907", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0035907", "url": "https://bgee.org/?page=gene&gene_id=FBgn0035907", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03184", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03184", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0035907", "url": "https://flybase.org/reports/FBgn0035907", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "38975", "url": "https://www.ncbi.nlm.nih.gov/gene/38975", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VSL6", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VSL6*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR004045", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004045", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005442", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005442", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010987", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010987", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036282", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036282", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG6662", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG6662", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MWPWCER", "url": "https://omabrowser.org/oma/group/MWPWCER/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VSL6", "url": "https://www.orthodb.org/?gene=Q9VSL6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43968", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43968", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43968:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43968:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13410", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13410", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13417", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13417", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-156590", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-156590", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-196836", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-196836", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_648237", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648237", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VSL6", "url": "https://www.uniprot.org/uniprotkb/Q9VSL6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VSL6-1", "url": "https://www.uniprot.org/uniprotkb/Q9VSL6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSNTQHLTIGSPKPVFPDDGILKLYSMRFCPYAHRVHLVLDAKKIPYHAIYINLRDKPEWFSLVSSSTKVPALELVKEQGNPVLIESLIICDYLDEKYPEVPLYPKDLLKKAQEKILIERFGQFINAFYYLLLHDNPEQLVDTDHYAGLVVYEEELKRRCTKFFGGDSPGMLDYMMWPWCERFDSLKYTFEQKFELSPERFPTLIKWRDLMIQDRAVKCFYLDGQTHAKYMNSRRSGQADYNMLYNEAKRVKLG", "length": 254, "header": "tr|Q9VSL6-1|Q9VSL6_DROME Isoform 1 of Glutathione S transferase O1 OS=Drosophila melanogaster OX=7227 GN=GstO1 PE=1 SV=1 CANONICAL=Q9VSL6-1" }, "isoforms": [ { "isoform_ac": "Q9VSL6-1", "url": "https://www.uniprot.org/uniprotkb/Q9VSL6/entry#Q9VSL6-1", "sequence": { "sequence": "MSNTQHLTIGSPKPVFPDDGILKLYSMRFCPYAHRVHLVLDAKKIPYHAIYINLRDKPEWFSLVSSSTKVPALELVKEQGNPVLIESLIICDYLDEKYPEVPLYPKDLLKKAQEKILIERFGQFINAFYYLLLHDNPEQLVDTDHYAGLVVYEEELKRRCTKFFGGDSPGMLDYMMWPWCERFDSLKYTFEQKFELSPERFPTLIKWRDLMIQDRAVKCFYLDGQTHAKYMNSRRSGQADYNMLYNEAKRVKLG", "length": 254, "header": "tr|Q9VSL6-1|Q9VSL6_DROME Isoform 1 of Glutathione S transferase O1 OS=Drosophila melanogaster OX=7227 GN=GstO1 PE=1 SV=1 CANONICAL=Q9VSL6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VSL6", "url": "https://www.uniprot.org/uniprotkb/Q9VSL6" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VSL6", "url": "https://www.uniprot.org/uniprotkb/Q9VSL6" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VSL6", "url": "https://www.uniprot.org/uniprotkb/Q9VSL6" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VSL6", "url": "https://www.uniprot.org/uniprotkb/Q9VSL6" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VSL6", "url": "https://www.uniprot.org/uniprotkb/Q9VSL6" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VSL6", "url": "https://www.uniprot.org/uniprotkb/Q9VSL6" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VSL6", "url": "https://www.uniprot.org/uniprotkb/Q9VSL6" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VSL6", "url": "https://www.uniprot.org/uniprotkb/Q9VSL6" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VSL6", "url": "https://www.uniprot.org/uniprotkb/Q9VSL6" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VSL6", "url": "https://www.uniprot.org/uniprotkb/Q9VSL6" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VSL6", "url": "https://www.uniprot.org/uniprotkb/Q9VSL6" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG6662", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG6662", "resource": "KEGG Pathway" }, { "id": "R-DME-156590", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-156590", "resource": "Reactome", "description": "Glutathione conjugation" }, { "id": "R-DME-196836", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-196836", "resource": "Reactome", "description": "Vitamin C (ascorbate) metabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AB32T4I1-1", "protein_name": "Glutathione S-transferase omega", "gene_name": "gsto2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFGIIVSKVFSSPPFSALCNTFFFKSLSAKRAHVCFDSIVYFNSTTLLQENTSTTTMASSPKCLGKECSAPGPVPNGQIRLYSMRFCPFAQRTRLVLTAKGVKHDIININLVSKPDWFLKKNPFGTVPVLETSSGQVIYESPITCEYLDEVYPEKKLLPSDPFERAQQKMLLELYSKVIPYFYKISMGKKRGEDVSTAEAEFTEKLVQLNEALANKKTKYFGGDSITMIDYLIWPWFERAEMMGVKHCLAKTPELRKWIELMFEDPVVKATMFNTDVHKVFFDSYMDGKPNYDYGL", "length": 296 }, "evidence": [ { "id": "HGNC:13312", "url": "https://alliancegenome.org/gene/HGNC:13312#orthology", "database": "AGR" }, { "id": "HGNC:23064", "url": "https://alliancegenome.org/gene/HGNC:23064#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-67", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-67#orthology", "database": "AGR" }, { "id": "MGI:1915464", "url": "https://alliancegenome.org/gene/MGI:1915464#orthology", "database": "AGR" }, { "id": "MGI:1342273", "url": "https://alliancegenome.org/gene/MGI:1342273#orthology", "database": "AGR" }, { "id": "RGD:70952", "url": "https://alliancegenome.org/gene/RGD:70952#orthology", "database": "AGR" }, { "id": "RGD:1310764", "url": "https://alliancegenome.org/gene/RGD:1310764#orthology", "database": "AGR" }, { "id": "FB:FBgn0035907", "url": "https://alliancegenome.org/gene/FB:FBgn0035907#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O09131-1", "protein_name": "Glutathione S-transferase omega-1", "gene_name": "Gsto1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGESSRSLGKGSAPPGPVPEGQIRVYSMRFCPFAQRTLMVLKAKGIRHEVININLKNKPEWFFEKNPLGLVPVLENSQGHLVTESVITCEYLDEAYPEKKLFPDDPYKKARQKMTLESFSKVPPLIASFVRSKRKEDSPNLREALENEFKKLEEGMDNYKSFLGGDSPSMVDYLTWPWFQRLEALELKECLAHTPKLKLWMAAMQQDPVASSHKIDAKTYREYLNLYLQDSPEACDYGL", "length": 240 }, "evidence": [ { "id": "HGNC:13312", "url": "https://alliancegenome.org/gene/HGNC:13312#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-67", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-67#orthology", "database": "AGR" }, { "id": "MGI:1342273", "url": "https://alliancegenome.org/gene/MGI:1342273#orthology", "database": "AGR" }, { "id": "RGD:70952", "url": "https://alliancegenome.org/gene/RGD:70952#orthology", "database": "AGR" }, { "id": "FB:FBgn0035907", "url": "https://alliancegenome.org/gene/FB:FBgn0035907#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P78417-1", "protein_name": "Glutathione S-transferase omega-1", "gene_name": "GSTO1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSGESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDYGL", "length": 241 }, "evidence": [ { "id": "HGNC:13312", "url": "https://alliancegenome.org/gene/HGNC:13312#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-67", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-67#orthology", "database": "AGR" }, { "id": "MGI:1342273", "url": "https://alliancegenome.org/gene/MGI:1342273#orthology", "database": "AGR" }, { "id": "RGD:70952", "url": "https://alliancegenome.org/gene/RGD:70952#orthology", "database": "AGR" }, { "id": "FB:FBgn0035907", "url": "https://alliancegenome.org/gene/FB:FBgn0035907#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6AXV9-1", "protein_name": "Glutathione S-transferase omega-2", "gene_name": "Gsto2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGDLTRCLGKGSCPPGPVPEGVIRIYSMRFCPYSHRTRLVLKAKSIRHEIININLKNKPDWYYTKHPFGQVPVLENSQCQLIYESVIACEYLDDVFPGRKLFPYDPYERARQKMLLELFCKVPQLSKECLVALRCGRDCTDLKVALRQELCNLEEILEYQNTTFFGGDSISMIDYLVWPWFERLDVYGLADCVNHTPMLRLWISSMKQDPAVCALHIDKNIFLGFLNLYFQNNPCAFDFGLCGPIVR", "length": 248 }, "evidence": [ { "id": "HGNC:23064", "url": "https://alliancegenome.org/gene/HGNC:23064#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-67", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-67#orthology", "database": "AGR" }, { "id": "MGI:1915464", "url": "https://alliancegenome.org/gene/MGI:1915464#orthology", "database": "AGR" }, { "id": "RGD:1310764", "url": "https://alliancegenome.org/gene/RGD:1310764#orthology", "database": "AGR" }, { "id": "FB:FBgn0035907", "url": "https://alliancegenome.org/gene/FB:FBgn0035907#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8K2Q2-1", "protein_name": "Glutathione S-transferase omega-2", "gene_name": "Gsto2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGDLSRCLGKGSCPPGPVPEGVIRIYSMRFCPYSHRARLVLKAKGIRHEVININLKSKPDWYYTKHPFGQIPVLENSQCQLVYESVIACEYLDDVYPGRKLFPYDPYERARQKMLLELFCKVPPLSKECLIALRCGRDCTDLKVALRQELCNMEEILEYQNTTFFGGDCISMIDYLVWPWFERLDVYGLADCVNHTPMLRLWIASMKQDPAVCALHTDKSVFLGFLNLYFQNNPCAFDFGLCNPIIR", "length": 248 }, "evidence": [ { "id": "HGNC:23064", "url": "https://alliancegenome.org/gene/HGNC:23064#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-67", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-67#orthology", "database": "AGR" }, { "id": "MGI:1915464", "url": "https://alliancegenome.org/gene/MGI:1915464#orthology", "database": "AGR" }, { "id": "RGD:1310764", "url": "https://alliancegenome.org/gene/RGD:1310764#orthology", "database": "AGR" }, { "id": "FB:FBgn0035907", "url": "https://alliancegenome.org/gene/FB:FBgn0035907#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H4Y5-1", "protein_name": "Glutathione S-transferase omega-2", "gene_name": "GSTO2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSGDATRTLGKGSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRECTNLKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGILDCVSHTPALRLWISAMKWDPTVCALLMDKSIFQGFLNLYFQNNPNAFDFGLC", "length": 243 }, "evidence": [ { "id": "HGNC:23064", "url": "https://alliancegenome.org/gene/HGNC:23064#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-67", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-67#orthology", "database": "AGR" }, { "id": "MGI:1915464", "url": "https://alliancegenome.org/gene/MGI:1915464#orthology", "database": "AGR" }, { "id": "RGD:1310764", "url": "https://alliancegenome.org/gene/RGD:1310764#orthology", "database": "AGR" }, { "id": "FB:FBgn0035907", "url": "https://alliancegenome.org/gene/FB:FBgn0035907#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VSL2-1", "protein_name": "1.8.5.1", "gene_name": "GstO3", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSSGKHLAKGSPKPVLPDDGVLRLYSMRFCPYAQRAHLVLNAKNVPYHSVYINLTEKPEWLVEVSPLLKVPALQLVAEKGEPSLIESLIIAEYLDDKYPENPLLPKDPLKRAQDKILLERFSSITSAFINILVQGTGLEDYWTALDIFEEELTKRGTPYFGGNKPGFVDYMIWPWFERLSVIELKLQKEYNFNESRFPKITKWIALLKADSVVQSFYATPEQHNEFWRTRKAGNANYDLLA", "length": 241 }, "evidence": [ { "id": "HGNC:13312", "url": "https://alliancegenome.org/gene/HGNC:13312#orthology", "database": "AGR" }, { "id": "HGNC:23064", "url": "https://alliancegenome.org/gene/HGNC:23064#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-67", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-67#orthology", "database": "AGR" }, { "id": "MGI:1915464", "url": "https://alliancegenome.org/gene/MGI:1915464#orthology", "database": "AGR" }, { "id": "MGI:1342273", "url": "https://alliancegenome.org/gene/MGI:1342273#orthology", "database": "AGR" }, { "id": "RGD:70952", "url": "https://alliancegenome.org/gene/RGD:70952#orthology", "database": "AGR" }, { "id": "RGD:1310764", "url": "https://alliancegenome.org/gene/RGD:1310764#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VSL3-1", "protein_name": "Pyrimidodiazepine synthase", "gene_name": "se", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSNGRHLAKGSPMPDVPEDGILRLYSMRFCPFAQRVHLVLDAKQIPYHSIYINLTDKPEWLLEKNPQGKVPALEIVREPGPPVLTESLLICEYLDEQYPLRPLYPRDPLKKVQDKLLIERFRAVLGAFFKASDGGDLEPFWSGLDIYERELARRGTEFFGGEQTGILDYMIWPWCERLELLKLQRGEDYNYDQSRFPQLTLWLERMKRDPAVMAFYMEAEVQAEFLRTRSLGRPNYNLLVKDA", "length": 243 }, "evidence": [ { "id": "HGNC:13312", "url": "https://alliancegenome.org/gene/HGNC:13312#orthology", "database": "AGR" }, { "id": "HGNC:23064", "url": "https://alliancegenome.org/gene/HGNC:23064#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-67", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-67#orthology", "database": "AGR" }, { "id": "MGI:1915464", "url": "https://alliancegenome.org/gene/MGI:1915464#orthology", "database": "AGR" }, { "id": "MGI:1342273", "url": "https://alliancegenome.org/gene/MGI:1342273#orthology", "database": "AGR" }, { "id": "RGD:70952", "url": "https://alliancegenome.org/gene/RGD:70952#orthology", "database": "AGR" }, { "id": "RGD:1310764", "url": "https://alliancegenome.org/gene/RGD:1310764#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VSL5-1", "protein_name": "1.8.5.1", "gene_name": "GstO2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MALPQKHFKRGSTKPELPEDGVPRFFSMAFCPFSHRVRLMLAAKHIEHHKIYVDLIEKPEWYKDFSPLGKVPALQLTGVKDQPTLVESLIIAEYLDQQYPQTRLFPTDPLQKALDKILIERFAPVVSAIYPVLTCNPNAPKDAIPNFENALDVFEVELGKRGTPYFAGQHIGIVDYMIWPWFERFPSMKINTEQKYELDTKRFEKLLKWRDLMTQDEVVQKTALDVQLHAEFQKSKTLGNPQYDIAFKGTP", "length": 251 }, "evidence": [ { "id": "HGNC:13312", "url": "https://alliancegenome.org/gene/HGNC:13312#orthology", "database": "AGR" }, { "id": "HGNC:23064", "url": "https://alliancegenome.org/gene/HGNC:23064#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-67", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-67#orthology", "database": "AGR" }, { "id": "MGI:1915464", "url": "https://alliancegenome.org/gene/MGI:1915464#orthology", "database": "AGR" }, { "id": "MGI:1342273", "url": "https://alliancegenome.org/gene/MGI:1342273#orthology", "database": "AGR" }, { "id": "RGD:70952", "url": "https://alliancegenome.org/gene/RGD:70952#orthology", "database": "AGR" }, { "id": "RGD:1310764", "url": "https://alliancegenome.org/gene/RGD:1310764#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Z339-1", "protein_name": "Glutathione S-transferase omega-1", "gene_name": "Gsto1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGASARSLGKGSAPPGPVPEGQIRVYSMRFCPFAQRTLMVLKAKGIRHEIININLKNKPEWFFEKNPFGLVPVLENTQGHLITESVITCEYLDEAYPEKKLFPDDPYEKACQKMTFELFSKVPSLVTSFIRAKRKEDHPGIKEELKKEFSKLEEAMANKRTAFFGGNSLSMIDYLIWPWFQRLEALELNECIDHTPKLKLWMATMQEDPVASSHFIDAKTYRDYLSLYLQDSPEACDYGL", "length": 241 }, "evidence": [ { "id": "HGNC:13312", "url": "https://alliancegenome.org/gene/HGNC:13312#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-67", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-67#orthology", "database": "AGR" }, { "id": "MGI:1342273", "url": "https://alliancegenome.org/gene/MGI:1342273#orthology", "database": "AGR" }, { "id": "RGD:70952", "url": "https://alliancegenome.org/gene/RGD:70952#orthology", "database": "AGR" }, { "id": "FB:FBgn0035907", "url": "https://alliancegenome.org/gene/FB:FBgn0035907#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "glutathione transferase activity", "id": "GO:0004364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004364", "evidence": [ { "database": "UniProtKB", "id": "Q9VSL6", "url": "https://www.uniprot.org/uniprotkb/Q9VSL6" } ], "pmid": "" }, { "name": "glutathione dehydrogenase (ascorbate) activity", "id": "GO:0045174", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045174", "evidence": [ { "database": "UniProtKB", "id": "Q9VSL6", "url": "https://www.uniprot.org/uniprotkb/Q9VSL6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VSL6", "url": "https://www.uniprot.org/uniprotkb/Q9VSL6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "glutathione metabolic process", "id": "GO:0006749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006749", "evidence": [ { "database": "UniProtKB", "id": "Q9VSL6", "url": "https://www.uniprot.org/uniprotkb/Q9VSL6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-DME-176054", "name": "GST dimers conjugate GSH with cytosolic substrates", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VSL3-1", "E1JJS1-1", "Q9VSL2-1", "Q9VSL5-1", "P41043-1", "A1Z7X7-1", "Q9VHD2-1", "Q9VSL6-1" ], "evidence": [ { "id": "R-DME-176054", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-176054" } ] }, { "id": "R-DME-198813", "name": "GSTO dimers reduce DeHA to AscH-", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-29450", "R-ALL-198827" ], "output_participant_list": [ "R-ALL-198816", "R-ALL-111745" ], "enzyme_list": [ "Q9VSL3-1", "Q9VSL2-1", "Q9VSL5-1", "Q9VSL6-1" ], "evidence": [ { "id": "R-DME-198813", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-198813" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-111745", "participant_name": "GSSG [cytosol]", "crossref": [ { "id": "58297", "database": "ChEBI", "url": "" }, { "id": "C00127", "database": "COMPOUND", "url": "" }, { "id": "ZINC000003870129", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-198816", "participant_name": "AscH- [cytosol]", "crossref": [ { "id": "50-81-7", "database": "CAS", "url": "" }, { "id": "44229109", "database": "PubChem Compound", "url": "" }, { "id": "ASCORBATE", "database": "AraCyc", "url": "" }, { "id": "C00072", "database": "COMPOUND", "url": "" }, { "id": "38290", "database": "ChEBI", "url": "" }, { "id": "ZINC000100006770", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-198827", "participant_name": "DeHA [cytosol]", "crossref": [ { "id": "58539", "database": "ChEBI", "url": "" }, { "id": "L-DEHYDRO-ASCORBATE", "database": "RiceCyc", "url": "" }, { "id": "ZINC000100082301", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-29450", "participant_name": "GSH [cytosol]", "crossref": [ { "id": "57925", "database": "ChEBI", "url": "" }, { "id": "ZINC000003830891", "database": "ZINC", "url": "" }, { "id": "C00051", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A1Z7X7", "gene_name": "GstT2", "activity": [ { "ec_number": "1.11.1.9", "activity": "2 glutathione + H2O2 = glutathione disulfide + 2 H2O.", "evidence": [ { "id": "A1Z7X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1Z7X7" } ] }, { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "A1Z7X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1Z7X7" } ] } ] }, { "uniprot_ac": "E1JJS1", "gene_name": "GstT3", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "E1JJS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1JJS1" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "E1JJS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1JJS1" } ] } ] }, { "uniprot_ac": "P41043", "gene_name": "GstS1", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "P41043", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P41043" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "P41043", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P41043" } ] } ] }, { "uniprot_ac": "Q9VHD2", "gene_name": "GstZ2", "activity": [ { "ec_number": "5.2.1.2", "activity": "4-maleylacetoacetate = 4-fumarylacetoacetate.", "evidence": [ { "id": "Q9VHD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VHD2" } ] }, { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "Q9VHD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VHD2" } ] }, { "ec_number": "5.2.1.2", "activity": "", "evidence": [ { "id": "Q9VHD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VHD2" } ] } ] }, { "uniprot_ac": "Q9VSL2", "gene_name": "GstO3", "activity": [ { "ec_number": "1.8.5.1", "activity": "L-dehydroascorbate + 2 glutathione = glutathione disulfide + L-ascorbate.", "evidence": [ { "id": "Q9VSL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSL2" } ] }, { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "Q9VSL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSL2" } ] } ] }, { "uniprot_ac": "Q9VSL3", "gene_name": "se", "activity": [ { "ec_number": "1.5.4.1", "activity": "2-amino-6-acetyl-3,7,8,9-tetrahydro-3H-pyrimido[4,5-b][1,4]diazepin-4-one + glutathione disulfide + H2O = 6-pyruvoyl-5,6,7,8-tetrahydropterin + 2 glutathione.", "evidence": [ { "id": "Q9VSL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSL3" } ] }, { "ec_number": "1.5.4.1", "activity": "", "evidence": [ { "id": "Q9VSL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSL3" } ] } ] }, { "uniprot_ac": "Q9VSL5", "gene_name": "GstO2", "activity": [ { "ec_number": "1.8.5.1", "activity": "L-dehydroascorbate + 2 glutathione = glutathione disulfide + L-ascorbate.", "evidence": [ { "id": "Q9VSL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSL5" } ] }, { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "Q9VSL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSL5" } ] } ] }, { "uniprot_ac": "Q9VSL6", "gene_name": "GstO1", "activity": [ { "ec_number": "1.8.5.1", "activity": "L-dehydroascorbate + 2 glutathione = glutathione disulfide + L-ascorbate.", "evidence": [ { "id": "Q9VSL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSL6" } ] }, { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "Q9VSL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSL6" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VSL6", 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"Q9VSL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSL9" } ] } ], "protein_names": [ { "name": "Isovaleryl-CoA dehydrogenase, mitochondrial", "type": "recommended", "evidence": [ { "id": "Q9VSL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSL9/entry#names_and_taxonomy" } ] }, { "name": "1.3.8.1", "type": "synonym", "evidence": [ { "id": "Q9VSL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSL9/entry#names_and_taxonomy" } ] }, { "name": "1.3.8.4", "type": "synonym", "evidence": [ { "id": "Q9VSL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSL9/entry#names_and_taxonomy" } ] }, { "name": "Butyryl-CoA dehydrogenase", "type": "synonym", "evidence": [ { "id": "Q9VSL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSL9/entry#names_and_taxonomy" } ] }, { "name": "CG6638-PA", "type": "synonym", "evidence": [ { "id": "NP_648239", "database": "RefSeq", "url": 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To a lesser extent, it also participates in the first step in fatty acid beta-oxidation, in which it catalyzes the proR-proR stereospecific alpha,beta-dehydrogenation of other saturated short-chain acyl-CoA thioesters such as pentanoyl-CoA, hexanoyl-CoA and butanoyl-CoA, using the electron transfer flavoprotein (ETF) as their physiologic electron acceptor.", "evidence": [ { "database": "UniProtKB", "id": "Q9VSL9", "url": "https://www.uniprot.org/uniprotkb/Q9VSL9#function" }, { "database": "UniProtKB", "id": "ARBA00094288", "url": "https://www.uniprot.org/uniprotkb/ARBA00094288#function" } ] } ], "disease": [ { "disease_id": "DOID:14753", "recommended_name": { "id": "DOID:14753", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14753", "name": "isovaleric acidemia", "description": "An organic acidemia that disrupts or prevents normal metabolism of the branched-chain amino acid leucine." }, "synonyms": [ { "id": "DOID:14753", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14753", "name": "Isovaleryl-CoA dehydrogenase deficiency", "description": "" }, { "id": "DOID:14753", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14753", "name": "isovaleric acid CoA dehydrogenase deficiency", "description": "" }, { "id": "DOID:14753", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14753", "name": "isovaleric aciduria", "description": "" }, { "id": "MONDO:0009475", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009475", "name": "isovaleric acidemia", "description": "Isovaleric acidemia (IVA) is an autosomal recessively inherited organic aciduria characterized by a deficiency in isovaleryl-CoA dehydrogenase, that has wide clinical variability and that can present in infancy with acute manifestations of vomiting, failure to thrive, seizures, lethargy, a characteristic ''sweaty feet'' odor, acute pancreatitis and mild to severe developmental delay or in childhood with metabolic acidosis (brought on by prolonged fasting, an increased intake of protein-rich food or infections) and that can be fatal if not treated immediately. Chronic intermittent presentations and asymptomatic patients have also been reported." }, { "id": "MONDO:0009475", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009475", "name": "Isovalericacidemia", "description": "" }, { "id": "MONDO:0009475", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009475", "name": "isovaleric acid CoA dehydrogenase deficiency", "description": "" }, { "id": "MONDO:0009475", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009475", "name": "isovaleric acidemia", "description": "" }, { "id": "MONDO:0009475", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009475", "name": "isovaleryl-CoA dehydrogenase deficiency", "description": "" }, { "id": "MONDO:0009475", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009475", "name": "IVA", "description": "" }, { "id": "MONDO:0009475", "resource": "MONDO", "url": 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"categories": [ "Protein Classification" ] }, { "id": "IPR009075", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009075", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009100", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009100", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013786", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013786", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034183", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034183", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036250", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036250", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037069", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037069", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046373", "url": 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"categories": [ "Protein Classification", "Other" ] }, { "id": "PF02770", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02770", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02771", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02771", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-70895", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-70895", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_648239", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648239", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "24004", "url": "https://www.rhea-db.org/rhea/24004", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "43456", "url": "https://www.rhea-db.org/rhea/43456", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "43464", "url": "https://www.rhea-db.org/rhea/43464", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "47196", "url": "https://www.rhea-db.org/rhea/47196", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q9VSL9", "url": "https://www.uniprot.org/uniprotkb/Q9VSL9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VSL9-1", "url": "https://www.uniprot.org/uniprotkb/Q9VSL9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALRFVAQSCRSLLQRGDRPLSWTRTLAHYPVNDAMFGLDEDRQKLREVAFNFFQKELAPLAKEIDKLDNFKDMRPFWKKLGALGFLGITAEPDFGGTGGSYLDHCIIMEEFSRAAGGVALSYGAHSNLCINQLTKNGTPEQKEKYLPKLCSGEHVGGLAMSEPGAGSDVVSMKLRAERKGDYYVLNGSKFWITNGSDADTLIVYAKTGGSGVPDKHGITAFIVETAWEGFSVAQKLDKLGMRGSSTCELVFQDLKVPAKNILGQENRGVYVLMSGLDFERLVLAAGPVGLMQAACDVAFDYAHQRKQMNKLIGEFQLLQGKMADMYTTLSACRSYLYTVARSCDAGNRSPKDCAGVILYTAEKATKVALDAIQILGGNGYINENPTGRILRDAKLYEIGAGTSEIRRWLIGRQLNQEYK", "length": 420, "header": "tr|Q9VSL9-1|Q9VSL9_DROME Isoform 1 of Isovaleryl-CoA dehydrogenase, mitochondrial OS=Drosophila melanogaster OX=7227 GN=Ivd PE=1 SV=1 CANONICAL=Q9VSL9-1" }, "isoforms": [ { "isoform_ac": "Q9VSL9-1", "url": "https://www.uniprot.org/uniprotkb/Q9VSL9/entry#Q9VSL9-1", "sequence": { "sequence": "MALRFVAQSCRSLLQRGDRPLSWTRTLAHYPVNDAMFGLDEDRQKLREVAFNFFQKELAPLAKEIDKLDNFKDMRPFWKKLGALGFLGITAEPDFGGTGGSYLDHCIIMEEFSRAAGGVALSYGAHSNLCINQLTKNGTPEQKEKYLPKLCSGEHVGGLAMSEPGAGSDVVSMKLRAERKGDYYVLNGSKFWITNGSDADTLIVYAKTGGSGVPDKHGITAFIVETAWEGFSVAQKLDKLGMRGSSTCELVFQDLKVPAKNILGQENRGVYVLMSGLDFERLVLAAGPVGLMQAACDVAFDYAHQRKQMNKLIGEFQLLQGKMADMYTTLSACRSYLYTVARSCDAGNRSPKDCAGVILYTAEKATKVALDAIQILGGNGYINENPTGRILRDAKLYEIGAGTSEIRRWLIGRQLNQEYK", "length": 420, "header": "tr|Q9VSL9-1|Q9VSL9_DROME Isoform 1 of Isovaleryl-CoA dehydrogenase, mitochondrial OS=Drosophila melanogaster OX=7227 GN=Ivd PE=1 SV=1 CANONICAL=Q9VSL9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VSL9", "url": "https://www.uniprot.org/uniprotkb/Q9VSL9" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VSL9", "url": "https://www.uniprot.org/uniprotkb/Q9VSL9" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VSL9", "url": "https://www.uniprot.org/uniprotkb/Q9VSL9" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VSL9", "url": "https://www.uniprot.org/uniprotkb/Q9VSL9" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VSL9", "url": "https://www.uniprot.org/uniprotkb/Q9VSL9" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VSL9", "url": "https://www.uniprot.org/uniprotkb/Q9VSL9" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VSL9", "url": "https://www.uniprot.org/uniprotkb/Q9VSL9" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VSL9", "url": "https://www.uniprot.org/uniprotkb/Q9VSL9" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VSL9", "url": "https://www.uniprot.org/uniprotkb/Q9VSL9" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VSL9", "url": "https://www.uniprot.org/uniprotkb/Q9VSL9" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VSL9", "url": "https://www.uniprot.org/uniprotkb/Q9VSL9" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG6638", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG6638", "resource": "KEGG Pathway" }, { "id": "R-DME-70895", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-70895", "resource": "Reactome", "description": "Branched-chain amino acid catabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7G720-1", "protein_name": "Isovaleryl-CoA dehydrogenase, mitochondrial", "gene_name": "Ivd", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MATAIRLLGRRVSSWRLRPSPLVVSQRASSMLPVDDAINGLNEEQKQLRQTISKFLHENLVPKAQEIDHSNEFKDLREFWKQLGSLGVLGITAPVQYGGSGLGYLEHVLVMEEISRASGAVGLSYGAHSNLCVNQIVRNGNEAQKEKYLPKLISGEFIGALAMSEPNAGSDVVSMRLKAEKKVPVLSSGAAVLWTEPGQETSANSQHPASPLGDHYILNGNKFWITNGPDADVLVVYAKTDLSAVPASRGITAFIVEKGMPGFSTSKKLDKLGMRGSNTCELIFEDCKVPAANILGQESKGVYVLMSGLDLERLVLAGGPLGIMQAVLDHTIPYLHVREAFGQKIGHFQLMQGKMADMYTRLMACRQYVYNVAKACDEGHIIGKDCAGVILYTAECATQVALDGIQCLGGNGYINDFPMGRFLRDAKLYEIGAGTSEVRRLIIGRAFNADFR", "length": 452 }, "evidence": [ { "id": "Q9VSL9", "url": "https://omabrowser.org/oma/group/Q9VSL9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P12007-1", "protein_name": "Isovaleryl-CoA dehydrogenase, mitochondrial", "gene_name": "Ivd", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATAVRLLGRRVSSWRLRPLPSPLAVPQRAHSMLPVDDDINGLNEEQKQLRHTISKFVQENLAPKAQEIDQSNDFKNLREFWKQLGSLGVLGITAPVQYGGSGLGYLEHVLVMEEISRASAAVGLSYGAHSNLCINQIVRNGNEAQKEKYLPKLISGEFIGALAMSEPNAGSDVVSMRLKAEKKGDHYVLNGNKFWITNGPDADVLVVYAKTDLTAVPASRGITAFIVEKDMPGFSTSKKLDKLGMRGSNTCELVFEDCKVPAANILSQESKGVYVLMSGLDLERLVLAGGPLGIMQAVLDHTIPYLHVREAFGQKIGQFQLMQGKMADMYTRLMACRQYVYNVARACDEGHITAKDCAGVILYTAECATQVALDGIQCLGGNGYINDFPMGRFLRDAKLYEIGGGTSEVRRLVIGRAFNADFR", "length": 424 }, "evidence": [ { "id": "RGD:2936", "url": "https://alliancegenome.org/gene/RGD:2936#orthology", "database": "AGR" }, { "id": "HGNC:6186", "url": "https://alliancegenome.org/gene/HGNC:6186#orthology", "database": "AGR" }, { "id": "MGI:1929242", "url": "https://alliancegenome.org/gene/MGI:1929242#orthology", "database": "AGR" }, { "id": "FB:FBgn0035911", "url": "https://alliancegenome.org/gene/FB:FBgn0035911#orthology", "database": "AGR" }, { "id": "Q9VSL9", "url": "https://omabrowser.org/oma/group/Q9VSL9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P26440-1", "protein_name": "Isovaleryl-CoA dehydrogenase, mitochondrial", "gene_name": "IVD", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEMATATRLLGWRVASWRLRPPLAGFVSQRAHSLLPVDDAINGLSEEQRQLRQTMAKFLQEHLAPKAQEIDRSNEFKNLREFWKQLGNLGVLGITAPVQYGGSGLGYLEHVLVMEEISRASGAVGLSYGAHSNLCINQLVRNGNEAQKEKYLPKLISGEYIGALAMSEPNAGSDVVSMKLKAEKKGNHYILNGNKFWITNGPDADVLIVYAKTDLAAVPASRGITAFIVEKGMPGFSTSKKLDKLGMRGSNTCELIFEDCKIPAANILGHENKGVYVLMSGLDLERLVLAGGPLGLMQAVLDHTIPYLHVREAFGQKIGHFQLMQGKMADMYTRLMACRQYVYNVAKACDEGHCTAKDCAGVILYSAECATQVALDGIQCFGGNGYINDFPMGRFLRDAKLYEIGAGTSEVRRLVIGRAFNADFH", "length": 426 }, "evidence": [ { "id": "RGD:2936", "url": "https://alliancegenome.org/gene/RGD:2936#orthology", "database": "AGR" }, { "id": "HGNC:6186", "url": "https://alliancegenome.org/gene/HGNC:6186#orthology", "database": "AGR" }, { "id": "MGI:1929242", "url": "https://alliancegenome.org/gene/MGI:1929242#orthology", "database": "AGR" }, { "id": "FB:FBgn0035911", "url": "https://alliancegenome.org/gene/FB:FBgn0035911#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3SZI8-1", "protein_name": "Isovaleryl-CoA dehydrogenase, mitochondrial", "gene_name": "IVD", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MATAAWLLGRRVASWRMRPPLQSLAGLITQRTNSLLPVDDAVNGLNEEQKQLRQTVAKFLQEHLAPQAQEIDQSNEFKNLREFWKQLGNLGVLGITAPVQYGGSGLGFLENVLVMEEISRVSGAVGLSYGAHSNLCINQIVRNGNETQKEKYLPKLISGEYIGALAMSEPNAGSDVVSMKLKAEKKGDHYVLNGNKFWITNGPDADVLVVYAKTDVTAVPASRGITAFIVEKGMPGFSTSKKLDKLGMRGSNTCELVFEDCEVPAANILGHLGKGVYVLMSGLDLERLVLAGGPLGIMQAVLDHTIPYLHMREAFGQKIGHFQLMQGKMADMYTRLMACRQYVYNVAKACDEGHCTTKDCAGVILYSAECATQVALDGIQCLGGNGYINDFPMGRFLRDAKLYEIGAGTSEVRRLVIGRAFNADFH", "length": 426 }, "evidence": [ { "id": "Q9VSL9", "url": "https://omabrowser.org/oma/group/Q9VSL9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54W88-1", "protein_name": "Isovaleryl-CoA dehydrogenase, mitochondrial", "gene_name": "ivdA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFRSLKKSSNILGFIKSSSSNKNIISRSIFTGRDINGFDETLLQLQESVREFAQNELAPIAADVDKNNLFPNEMWKKMGDLGLLGITAPSKYGGLDLGYTAHCIAMEELSRASASVALSYGAHSNLCINQITRNANEAQKDKYLPKLISGDFVGALAMSEPNAGSDVVSMKTNAKKTEGGWLLNGNKMWITNGPDANVLVVYAKTDINAGSKGITAFLIEKEMKGFSTGQKLDKLGMRGSNTCELVFEDCFVPDENVLGTVGGGVKVLMSGLDYERLVLSAGPLGIMQACMDNVVPYLHQREQFGKPIGEFQLMQGKVADMYTLLNASRSYVYSVAKSADAGYTSRKDCAAVILYTAENATQMALQAIQTLGGNGYINEFPTGRLLRDAKLYEIGAGTSEIRRMLIGRELFAETK", "length": 415 }, "evidence": [ { "id": "Q9VSL9", "url": "https://omabrowser.org/oma/group/Q9VSL9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9JHI5-1", "protein_name": "Isovaleryl-CoA dehydrogenase, mitochondrial", "gene_name": "Ivd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATAIRLLGRRVSSWRLRPSPSPLAVPRRAHSILPVDDDINGLNEEQKQLRHTISKFLQENLAPKAQEIDQTNDFKNLREFWKQLGSLGVLGITAPVQYGGSGLGYLEHVLVMEEISRASGAVGLSYGAHSNLCVNQIVRNGNEAQKEKYLPKLISGEFIGALAMSEPNAGSDVVSMKLKAEKKGDHYVLNGNKFWITNGPDADILVVYAKTDLTAVPASRGITAFIVEKGMPGFSTSKKLDKLGMRGSNTCELVFEDCKVPAANVLSQESKGVYVLMSGLDLERLVLAGGPLGIMQAVLDHTIPYLHVREAFGQKIGQFQLMQGKMADMYTRLMASRQYVYNVAKACDEGHIIPKDCAGVILYAAECATQVALDGIQCLGGNGYINDFPMGRFLRDAKLYEIGAGTSEVRRLVIGRAFNADFR", "length": 424 }, "evidence": [ { "id": "RGD:2936", "url": "https://alliancegenome.org/gene/RGD:2936#orthology", "database": "AGR" }, { "id": "HGNC:6186", "url": "https://alliancegenome.org/gene/HGNC:6186#orthology", "database": "AGR" }, { "id": "MGI:1929242", "url": "https://alliancegenome.org/gene/MGI:1929242#orthology", "database": "AGR" }, { "id": "FB:FBgn0035911", "url": "https://alliancegenome.org/gene/FB:FBgn0035911#orthology", "database": "AGR" }, { "id": "Q9VSL9", "url": "https://omabrowser.org/oma/group/Q9VSL9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9SWG0-1", "protein_name": "Isovaleryl-CoA dehydrogenase, mitochondrial", "gene_name": "IVD", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MQRFFSARSILGYAVKTRRRSFSSRSSSLLFDDTQLQFKESVSKFAQDNIAPHAERIDKTNSFPKDVNLWKLMGEFNLHGITAPEEYGGLGLGYLYHCIAMEEISRASGSVALSYGAHSNLCINQLVRNGTAAQKEKYLPKLISGEHVGALAMSEPNAGSDVVGMKCKAEKVDGGYILNGNKMWCTNGPSAETLVVYAKTDTKAGSKGITAFIIEKGMTGFSTAQKLDKLGMRGSDTCELVFENCFVPEENILDKEGKGVYVLMSGLDLERLVLAAGPLGIMQACLDNVLPYIRQREQFGRPVGEFQFIQGKVADMYTALQSSRSYVYSVARDCDNGKVDPKDCAGTILCAAERATQVALQAIQCLGGNGYINEYATGRLLRDAKLYEIGAGTSEIRRIVIGRELFKEE", "length": 409 }, "evidence": [ { "id": "Q9VSL9", "url": "https://omabrowser.org/oma/group/Q9VSL9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "3-methylbutanoyl-CoA dehydrogenase activity", "id": "GO:0008470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008470", "evidence": [ { "database": "UniProtKB", "id": "Q9VSL9", "url": "https://www.uniprot.org/uniprotkb/Q9VSL9" } ], "pmid": "" }, { "name": "flavin adenine dinucleotide binding", "id": "GO:0050660", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050660", "evidence": [ { "database": "UniProtKB", "id": "Q9VSL9", "url": "https://www.uniprot.org/uniprotkb/Q9VSL9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9VSL9", "url": "https://www.uniprot.org/uniprotkb/Q9VSL9" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "Q9VSL9", "url": "https://www.uniprot.org/uniprotkb/Q9VSL9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "L-leucine catabolic process", "id": "GO:0006552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006552", "evidence": [ { "database": "UniProtKB", "id": "Q9VSL9", "url": "https://www.uniprot.org/uniprotkb/Q9VSL9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 137, "end_pos": 139, "annotation": "n_glycosylation_sequon" }, { "start_pos": 187, "end_pos": 189, "annotation": "n_glycosylation_sequon" }, { "start_pos": 195, "end_pos": 197, "annotation": "n_glycosylation_sequon" }, { "start_pos": 348, "end_pos": 350, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "24004", "name": "", "equation": "butanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein]", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VSL9-1", "Q9VVU1-1", "Q9VDT1-1", "Q9VGC2-1" ], "evidence": [ { "id": "24004", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/24004" } ] }, { "id": "43456", "name": "", "equation": "pentanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-pentenoyl-CoA + reduced [electron-transfer flavoprotein]", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VSL9-1", "Q9VDT1-1", "Q9VGC2-1" ], "evidence": [ { "id": "43456", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/43456" } ] }, { "id": "43464", "name": "", "equation": "hexanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-hexenoyl-CoA + reduced [electron-transfer flavoprotein]", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VSL9-1", "Q9VVU1-1", "Q9VDT1-1", "Q9VGC2-1" ], "evidence": [ { "id": "43464", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/43464" } ] }, { "id": "47196", "name": "", "equation": "a short-chain 2,3-saturated fatty acyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VVU1-1", "Q9VSL9-1" ], "evidence": [ { "id": "47196", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/47196" } ] }, { "id": "R-DME-70745", "name": "isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [ "R-ALL-70715" ], "output_participant_list": [], "enzyme_list": [ "Q9VSL9-1" ], "evidence": [ { "id": "R-DME-70745", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-70745" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-70715", "participant_name": "ISV-CoA [mitochondrial matrix]", "crossref": [ { "id": "57345", "database": "ChEBI", "url": "" }, { "id": "ZINC000008551494", "database": "ZINC", "url": "" }, { "id": "C02939", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "Q9VDT1", "gene_name": "Arc42", "activity": [ { "ec_number": "1.3.8.1", "activity": "a short-chain 2,3-saturated fatty acyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein].", "evidence": [ { "id": "Q9VDT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VDT1" } ] }, { "ec_number": "1.3.8.1", "activity": "", "evidence": [ { "id": "Q9VDT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VDT1" } ] } ] }, { "uniprot_ac": "Q9VGC2", "gene_name": "Dmel\\CG4860", "activity": [ { "ec_number": "1.3.8.1", "activity": "a short-chain 2,3-saturated fatty acyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein].", "evidence": [ { "id": "Q9VGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VGC2" } ] }, { "ec_number": "1.3.8.1", "activity": "", "evidence": [ { "id": "Q9VGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VGC2" } ] } ] }, { "uniprot_ac": "Q9VSL9", "gene_name": "Ivd", "activity": [ { "ec_number": "1.3.8.4", "activity": "3-methylbutanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = 3-methylbut-2-enoyl-CoA + reduced [electron-transfer flavoprotein].", "evidence": [ { "id": "Q9VSL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSL9" } ] }, { "ec_number": "1.3.8.1", "activity": "a short-chain 2,3-saturated fatty acyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein].", "evidence": [ { "id": "Q9VSL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSL9" } ] }, { "ec_number": "1.3.8.4", "activity": "", "evidence": [ { "id": "Q9VSL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSL9" } ] }, { "ec_number": "1.3.8.1", "activity": "", "evidence": [ { "id": "Q9VSL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSL9" } ] } ] }, { "uniprot_ac": "Q9VVU1", "gene_name": "GH07925p", "activity": [ { "ec_number": "1.3.8.1", "activity": "a short-chain 2,3-saturated fatty acyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein].", "evidence": [ { "id": "Q9VVU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVU1" } ] }, { "ec_number": "1.3.8.5", "activity": "2-methylpropanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = 2-methylpropenoyl-CoA + reduced [electron-transfer flavoprotein].", "evidence": [ { "id": "Q9VVU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVU1" } ] }, { "ec_number": "1.3.8.5", "activity": "", "evidence": [ { "id": "Q9VVU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVU1" } ] }, { "ec_number": "1.3.8.1", "activity": "", "evidence": [ { "id": "Q9VVU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVU1" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VSL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSL9" }, { "id": "PF00441", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00441" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Acyl-CoA dehydrogenase/oxidase C-terminal", "eco_id": "ECO_0000259", "start_pos": 267, "end_pos": 415, "start_aa": "Asn", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q9VSL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSL9" }, { "id": "PF02771", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02771" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Acyl-CoA dehydrogenase/oxidase N-terminal", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 154, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q9VSL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSL9" }, { "id": "PF02770", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02770" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Acyl-CoA oxidase/dehydrogenase middle", "eco_id": "ECO_0000259", "start_pos": 159, "end_pos": 254, "start_aa": "Leu", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.3.8.4", "ec_name": "3-methylbutanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = 3-methylbut-2-enoyl-CoA + reduced [electron-transfer flavoprotein].", "evidence": [ { "id": "1.3.8.4", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.8.4" }, { "id": "1.3.8.4", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.3.8.4" } ] }, { "ec_number": "1.3.8.1", "ec_name": "a short-chain 2,3-saturated fatty acyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein].", "evidence": [ { "id": "1.3.8.1", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.8.1" }, { "id": "1.3.8.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.3.8.1" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 137, "end_pos": 139 }, { "start_pos": 187, "end_pos": 189 }, { "start_pos": 195, "end_pos": 197 }, { "start_pos": 348, "end_pos": 350 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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"name": "Sperm-Leucylaminopeptidase 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_729394" }, "gene_names": [ { "name": "S-Lap2", "type": "recommended", "evidence": [ { "id": "Q9VSM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSM7" } ] }, { "name": "BcDNA:LP03301", "type": "synonym", "evidence": [ { "id": "NP_729394", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_729394" } ] }, { "name": "CG32351", "type": "synonym", "evidence": [ { "id": "NP_729394", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_729394" }, { "id": "Q9VSM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSM7" } ] }, { "name": "Dmel\\CG32351", "type": "synonym", "evidence": [ { "id": "NP_729394", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_729394" } ] }, { "name": "FBgn0052351", "type": "synonym", "evidence": [ { "id": "NP_729394", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_729394" } ] }, { "name": "Lap CG32351", "type": "synonym", "evidence": [ { "id": "NP_729394", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_729394" } ] }, { "name": "S-LAP 2", "type": "synonym", "evidence": [ { "id": "NP_729394", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_729394" } ] }, { "name": "S-Lap 2", "type": "synonym", "evidence": [ { "id": "NP_729394", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_729394" } ] }, { "name": "S-Lap2", "type": "synonym", "evidence": [ { "id": "NP_729394", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_729394" } ] }, { "name": "anon-WO0140519.85", "type": "synonym", "evidence": [ { "id": "NP_729394", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_729394" } ] } ], "protein_names": [ { "name": "Crystallomitin S-Lap2", "type": "recommended", "evidence": [ { "id": "Q9VSM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSM7/entry#names_and_taxonomy" } ] }, { "name": "CG32351-PA", "type": "synonym", "evidence": [ { "id": "NP_729394", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_729394" } ] }, { "name": "Inactive sperm-leucylaminopeptidase 2", "type": "synonym", "evidence": [ { "id": "Q9VSM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSM7/entry#names_and_taxonomy" } ] }, { "name": "S-Lap2-PA", "type": "synonym", "evidence": [ { "id": "NP_729394", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_729394" } ] }, { "name": "Sperm-Leucylaminopeptidase 2", "type": "synonym", "evidence": [ { "id": "NP_729394", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_729394" } ] } ], "function": [ { "annotation": "Structural component of the paracrystalline material found in the major mitochondrial derivative of male germ cells.", "evidence": [ { "database": "UniProtKB", "id": "Q9VSM7", "url": "https://www.uniprot.org/uniprotkb/Q9VSM7#function" }, { "database": "PubMed", "id": "30802236", "url": "https://glygen.org/publication/PubMed/30802236" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VSM7", "url": "https://www.uniprot.org/uniprotkb/Q9VSM7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "S-Lap2", "url": "https://www.uniprot.org/uniprotkb/Q9VSM7", "locus": { "chromosome": "3L", "start_pos": 8622091, "end_pos": 8619888, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0052351", "url": "https://www.ensemblgenomes.org/id/FBgn0052351" } ] } } ], "crossref": [ { "id": "FB:FBgn0052351", "url": "https://alliancegenome.org/gene/FB:FBgn0052351", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "Q9VSM7", "url": "https://alphafold.ebi.ac.uk/entry/Q9VSM7", "database": "AlphaFoldDB", "categories": [] }, { "id": "FBgn0052351", "url": "https://bgee.org/?page=gene&gene_id=FBgn0052351", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "3.4.11.1", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.11.1&UniProtAcc=Q9VSM7", "database": "BRENDA", "categories": [ "Enzyme and Pathway" ] }, { "id": "FBgn0052351", "url": "https://flybase.org/reports/FBgn0052351", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "326209", "url": "https://www.ncbi.nlm.nih.gov/gene/326209", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VSM7", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VSM7*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR000819", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000819", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008283", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008283", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG32351", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG32351", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SQMINQM", "url": "https://omabrowser.org/oma/group/SQMINQM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VSM7", "url": "https://www.orthodb.org/?gene=Q9VSM7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11963", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11963", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11963:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11963:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00883", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00883", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02789", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02789", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_729394", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_729394", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VSM7", "url": "https://www.uniprot.org/uniprotkb/Q9VSM7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VSM7-1", "url": "https://www.uniprot.org/uniprotkb/Q9VSM7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFRFSRNAITRACSLSIRRPEVIRHRRYASQAINQMLQLQQMEICADPPSRGLVVGVYADEEDKNDAGILTPTGWKYNVQKTHGRLLEVLRMSGPMPKRGETRLLFAVEPERVPYYSAVAVIGLGKECLGYNPYEVLDEQKEAIRRSVADACRILAELDTDRIEVENCGHAESAAEGAALGIWIYQELRDPKRRISVPSIDLYATKDEICDIEGWRIGLQKAAAQNLTRQLQEMPSNLLTPTAFAQNVVEVLCKSGVNVEVKVEGWAESQSMHAFLAVGKASCEPPIFLELSYYGTCAEERPIVLVGQGVTYDAGGLCLKEKQELFHMRGDMTGAAVVVATCRAVAGLRLPVNIRGLIPLCENVIGCNSFRPGDMVKSMNGKTIEVQCTDHEDVLVLADALLYGQNFCPKCIIDIGTCSGYMRQALDEAACGVFTNSEILWQQIKHASMHTGDRVWRFPLWNYYSKAVRAGGRSDVQNYGIGRGGRPCKAAAFLREFVPCGQWMHIDATNVMITRGDEFEYLREGMAGRPTRTLIEFIAQSICKDTAPKLNK", "length": 552, "header": "sp|Q9VSM7-1|SPRO2_DROME Isoform 1 of Crystallomitin S-Lap2 OS=Drosophila melanogaster OX=7227 GN=S-Lap2 PE=1 SV=1 CANONICAL=Q9VSM7-1" }, "isoforms": [ { "isoform_ac": "Q9VSM7-1", "url": "https://www.uniprot.org/uniprotkb/Q9VSM7/entry#Q9VSM7-1", "sequence": { "sequence": "MFRFSRNAITRACSLSIRRPEVIRHRRYASQAINQMLQLQQMEICADPPSRGLVVGVYADEEDKNDAGILTPTGWKYNVQKTHGRLLEVLRMSGPMPKRGETRLLFAVEPERVPYYSAVAVIGLGKECLGYNPYEVLDEQKEAIRRSVADACRILAELDTDRIEVENCGHAESAAEGAALGIWIYQELRDPKRRISVPSIDLYATKDEICDIEGWRIGLQKAAAQNLTRQLQEMPSNLLTPTAFAQNVVEVLCKSGVNVEVKVEGWAESQSMHAFLAVGKASCEPPIFLELSYYGTCAEERPIVLVGQGVTYDAGGLCLKEKQELFHMRGDMTGAAVVVATCRAVAGLRLPVNIRGLIPLCENVIGCNSFRPGDMVKSMNGKTIEVQCTDHEDVLVLADALLYGQNFCPKCIIDIGTCSGYMRQALDEAACGVFTNSEILWQQIKHASMHTGDRVWRFPLWNYYSKAVRAGGRSDVQNYGIGRGGRPCKAAAFLREFVPCGQWMHIDATNVMITRGDEFEYLREGMAGRPTRTLIEFIAQSICKDTAPKLNK", "length": 552, "header": "sp|Q9VSM7-1|SPRO2_DROME Isoform 1 of Crystallomitin S-Lap2 OS=Drosophila melanogaster OX=7227 GN=S-Lap2 PE=1 SV=1 CANONICAL=Q9VSM7-1" }, "locus": { "chromosome": "3L", "start_pos": 8619888, "end_pos": 8622091, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0076639", "url": "https://www.ensemblgenomes.org/id/FBtr0076639" }, { "database": "Ensembl Peptide", "id": "FBpp0076363", "url": "https://www.ensemblgenomes.org/id/FBpp0076363" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VSM7", "url": "https://www.uniprot.org/uniprotkb/Q9VSM7" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VSM7", "url": "https://www.uniprot.org/uniprotkb/Q9VSM7" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "Expansion and functional diversification of a leucyl aminopeptidase family that encodes the major protein constituents of Drosophila sperm.", "journal": "BMC Genomics", "date": "2011", "authors": "Dorus S., Karr T.L., Wilkin E.C.", "evidence": [ { "database": "UniProtKB", "id": "Q9VSM7", "url": "https://www.uniprot.org/uniprotkb/Q9VSM7" } ], "reference": [ { "type": "PubMed", "id": "21466698", "url": "https://glygen.org/publication/PubMed/21466698" } ] }, { "title": "Sperm-Leucylaminopeptidases are required for male fertility as structural components of mitochondrial paracrystalline material in Drosophila melanogaster sperm.", "journal": "PLoS genetics", "date": "2019-02", "authors": "Laurinyecz Barbara, Vedelek Viktor, Kov\u00e1cs Attila L, Szilasi Kinga, Lipinszki Zolt\u00e1n, Slez\u00e1k Csilla, Darula Zsuzsanna, Juh\u00e1sz G\u00e1bor, Sinka Rita", "evidence": [ { "database": "UniProtKB", "id": "Q9VSM7", "url": "https://www.uniprot.org/uniprotkb/Q9VSM7" } ], "reference": [ { "type": "PubMed", "id": "30802236", "url": "https://glygen.org/publication/PubMed/30802236" } ] } ], "pathway": [ { "id": "dme:Dmel_CG32351", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG32351", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A1Z9G3-1", "protein_name": "Crystallomitin S-Lap5", "gene_name": "S-Lap5", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MASTRMISAFTRNPRLYQQVTAPWKSYNLFGTPLFNHRLQPADSQIWRGLADKCDNKTVIKGVVVGVYSKEGDGKEVKMTSSGEKFDDRTQGKVSELLRETGIKGELGKGKVFMNVDAEFRAVAVVGLGQEGAGFNDLENIDEGMENARVAAGVGARALQLQGCTEVFVDSMEYPEQAAEGSALAIWRYNSNKRKQDRTQVPKLDLYDSPDVDAWTRGLFKAESQNLARRLSDSPANQMTPTIFAQSAVDALCPCGVSVEVRSMDWIEMNHLNSFLMIAKGSCEPPVVLEVSYCGTAPEDRPILLLGKGLTYNSGGLCLRPKDCLHMYRGCMAGAAVCVAAVRAAAALSLPVNITAVLPLCENMPSGMAVKPGDVVTLLNGKTMGIVDVSKAGTVVLADPLLFAQTTYKPRLVVDLATVGYGVCAGLGESAAGLFTNSNFIAKQFEKAGGLTGDRLWRLPLWRYFKQLVTPNLTFDISNRGIGPASSCIAAAVLHELVPCADWAHIDIRNVGMLTRHNPLPYLLKDRMTGRPTRTIVQFLYQMACPESK", "length": 549 }, "evidence": [ { "id": "RGD:1307985", "url": "https://alliancegenome.org/gene/RGD:1307985#orthology", "database": "AGR" }, { "id": "MGI:1914238", "url": "https://alliancegenome.org/gene/MGI:1914238#orthology", "database": "AGR" }, { "id": "HGNC:18449", "url": "https://alliancegenome.org/gene/HGNC:18449#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A2BIC6-1", "protein_name": "Cytosol aminopeptidase", "gene_name": "lap3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLIPFRRALLTAIRKHNCRLFSDSTVTSSTRKGLVLGVYEQQSDSDGVSLTEAAAAFDRSLSGRLSEMLSLSGPPLKKGKSRIFYGLHQDFPSVVVVGLGKSDPGVCGKENWDNCKENIRAAVSAGCRQLQDLEVALVEVDPCGDDQSAAEGAVLGLFEYDELKTKKKVHVKTRPHGSVDAAAWQKGVLYGDGQNLARQLMEAPANHVTPTVFANTIEQKLSLFADRVIVHKRPQSWIEGEQMGAFLSVSKGSEEPPVFLELHYKGSSDSAQPPLVLVGKGITFDSGGISLKPSSGMDAMRADMGGAATVCSAIVTAAALKIPINIIGLAPLCENMPSGKANKPGDVVRAKNGKTIQIDNTDAEGRLILADALCYAHSFKPRAIINAATLTGAMDVALGSAATGVFTNSDWLWERLHKASVVTGDRVWRMPLFQHYTKQVTDSALADLNNVGKYSRSGGACTAAAFLKEFVSANHWAHLDIAGVMTNKDEVPYLRKGMSGRPTRTLVEFIAGLASDV", "length": 517 }, "evidence": [ { "id": "MGI:1914238", "url": "https://alliancegenome.org/gene/MGI:1914238#orthology", "database": "AGR" }, { "id": "HGNC:18449", "url": "https://alliancegenome.org/gene/HGNC:18449#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P28838-1", "protein_name": "Cytosol aminopeptidase", "gene_name": "LAP3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFLLPLPAAGRVVVRRLAVRRFGSRSLSTADMTKGLVLGIYSKEKEDDVPQFTSAGENFDKLLAGKLRETLNISGPPLKAGKTRTFYGLHQDFPSVVLVGLGKKAAGIDEQENWHEGKENIRAAVAAGCRQIQDLELSSVEVDPCGDAQAAAEGAVLGLYEYDDLKQKKKMAVSAKLYGSGDQEAWQKGVLFASGQNLARQLMETPANEMTPTRFAEIIEKNLKSASSKTEVHIRPKSWIEEQAMGSFLSVAKGSDEPPVFLEIHYKGSPNANEPPLVFVGKGITFDSGGISIKASANMDLMRADMGGAATICSAIVSAAKLNLPINIIGLAPLCENMPSGKANKPGDVVRAKNGKTIQVDNTDAEGRLILADALCYAHTFNPKVILNAATLTGAMDVALGSGATGVFTNSSWLWNKLFEASIETGDRVWRMPLFEHYTRQVVDCQLADVNNIGKYRSAGACTAAAFLKEFVTHPKWAHLDIAGVMTNKDEVPYLRKGMTGRPTRTLIEFLLRFSQDNA", "length": 519 }, "evidence": [ { "id": "RGD:1307985", "url": "https://alliancegenome.org/gene/RGD:1307985#orthology", "database": "AGR" }, { "id": "MGI:1914238", "url": "https://alliancegenome.org/gene/MGI:1914238#orthology", "database": "AGR" }, { "id": "HGNC:18449", "url": "https://alliancegenome.org/gene/HGNC:18449#orthology", "database": "AGR" }, { "id": "FB:FBgn0052351", "url": "https://alliancegenome.org/gene/FB:FBgn0052351#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q500X4-1", "protein_name": "Crystallomitin S-Lap7", "gene_name": "S-Lap7", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNKLRQIHCSLKNACVLCKPHVLSSAGVRFSCGDGKTMAKGVVVGLYQKEGDKDPKLTPAGHKIDQRVQGKLMKAICETKLDGRLGRGKVFHNIDTEFAAVAVVGVGLEGIGFNELEMLDEGMEFVRVAAGVGARSLQQQGITNVLVDGMDYAEQAAEGSQLAVWRFPDNLSKKNMPMVPTLELFESPDHEGWTRGIFKAEAQNLARRLSDAPANCMTPTMFAQAAVDALCPCGITVEVRTMDWIEAQRLNAFLMIAKGSCEPPVLLELSYCGTAPDDKPILFVGKGITFNSGALNLRPCRGMDEYRGSMSAAACCVAMMRCIAALSLPINVTCIIPLCENMPSGMSAKPGDVVTLLNGKSMAIRDLDKAGVVVLSDPLLYGQKTYLPRLVVDIATLNTGVKKAFGGGATGIWSNSHYIWKQFQRAGSISGDRVWRLPLWQYYRRQVTDERAYDLSNNGRGLASSCLAAAILHELVPCVDWAHLDTRGTGLLSKYGLVPYLTKKRMTGRPTRTLVQFVYQMACPEMK", "length": 527 }, "evidence": [ { "id": "RGD:1307985", "url": "https://alliancegenome.org/gene/RGD:1307985#orthology", "database": "AGR" }, { "id": "MGI:1914238", "url": "https://alliancegenome.org/gene/MGI:1914238#orthology", "database": "AGR" }, { "id": "HGNC:18449", "url": "https://alliancegenome.org/gene/HGNC:18449#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q68FS4-1", "protein_name": "Cytosol aminopeptidase", "gene_name": "Lap3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYLLPLPAAARVALRRLGVRGLWDRGLSTADMTKGLVLGIYSKDKDDDVPQFTSAGENFNKLVSGRLREMLNISGPPLKAGKTRTFYGLHQDFPSVVVVGLGKRSAGVDDQENWHEGKENIRAAVAAGCRQVQDLELPSVEVDPCGDAQAAAEGAVLGLYEYDDLKQKKKVAVSAKLHGSGDLEAWEKGVLFASGQNLARQLMESPANEMTPTRFAEVIEKNLKSASSKTEVHIRTKSWIEEQEMGSFLSVAKGSEEPPVFLEIHYTGSPNATEAPLVFVGKGITFDSGGISIKASANMDLMRADMGGAATICSAIVSAAKLNLPINIIGLAPLCENMPSGKANKPGDVVRARNGKTIQVDNTDAEGRLILADALCYAHTFNPKVIINAATLTGAMDVALGSGATGVFTNSSWLWNKLFEASVETGDRVWRMPLFEHYTRQVIDCQLADVNNLGKYRSAGACTAAAFLREFVTHTKWAHLDIAGVMTNKDEIPYLRKGMSGRPTRTLIEFLLRFSKDSS", "length": 519 }, "evidence": [ { "id": "RGD:1307985", "url": "https://alliancegenome.org/gene/RGD:1307985#orthology", "database": "AGR" }, { "id": "MGI:1914238", "url": "https://alliancegenome.org/gene/MGI:1914238#orthology", "database": "AGR" }, { "id": "HGNC:18449", "url": "https://alliancegenome.org/gene/HGNC:18449#orthology", "database": "AGR" }, { "id": "FB:FBgn0052351", "url": "https://alliancegenome.org/gene/FB:FBgn0052351#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7K2S9-1", "protein_name": "Crystallomitin loopin-1", "gene_name": "loopin-1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPSYKNMSLVRAGLRMVRQNRSGQSVIPSYRRYATSCKSPKGVVVGVYTKDGDKPSKTTANAVTLDDALGGKLLTLIRERGMDGTPGKGLLFSGFEGEYQAVAVVGVGKQGAAYNENEELDEGMENVRVAAGTGARALQLQGMYEVHVDSMDYPEQAAEGAALAVWRYNANKRKKNRIQTPKLDMYGKGDRDAWVRGLFKAESQNLARRLSDTPANMMTPSIFAQAAVDALCPCGVSVEVRSMDWIEDMNLNSFLMIAKGSCEPPLLLECSYCGTTPEDRPVLLLGQGLTFHSGGLCLKPKTGMDQYRGAMAGAAVCVGVLRAAAALSLPLNITAVMPLCEHMPSGMAVKCGDVVTLLNGTTMGIKNVDKAPVVQLADPLLYAQATYKPKLVIDIGTVAMGVNYAVGGGASGLWTTSKSVWQNFRKSGGLTGDRVWRFPLFKYYKQIVNKNITYDLCNTGRGPASSCLAAAILHTLVPCAEWAHLDIRGTGMTTTINPRPYLLKDSMTGRPTRTVIQFMYQMACSG", "length": 526 }, "evidence": [ { "id": "RGD:1307985", "url": "https://alliancegenome.org/gene/RGD:1307985#orthology", "database": "AGR" }, { "id": "MGI:1914238", "url": "https://alliancegenome.org/gene/MGI:1914238#orthology", "database": "AGR" }, { "id": "HGNC:18449", "url": "https://alliancegenome.org/gene/HGNC:18449#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q7K5K9-1", "protein_name": "Crystallomitin S-Lap8", "gene_name": "S-Lap8", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTRSQMISSLRRSTLGLFRCHKALIFARIPAFQQVRCKSEDGSCNTCNLQGVVVGLYAKDGDKGLKLSPGGEKFDDRVGGKITELIKESGLNGELGVGRLYQNIDKEYWAVAVVGLGKEGAGFNAEEVIDEGMENVRVCAAVGARALQLQGCTTCHVDGMEYPEQAAEGAAMAVWRYNVNKRKKNRIAIPKLELYGSTDQDAWTRGLFKAESQNLARRLSDTPANQMTPSIFAQATVDALCPCGVSVEVRSMDWIETQNLNSFLMVAKGSCEPPIILEVSYCGTSPEERPILMLGKGLTFNSGGLCLHPKRGMDEYRGAVSGAAVCVAAIRAAAALSLPINVSAVLPLCENMPSGMATKPGDVVTLLNGKTMRIKDISLAGTVLLADPLLYAQSTFKPKLVVEVGSMASGIRKGLGASATGLWTNNSFLWKNFQKAGALTGDRLWRMPLWRYFRKLVAPRASYDICSTGEGHASSCLAAAILYELVPCSDWVHLDTHGTGMLAKHGVPPYLLKDCMTGRPTRSIIQFLYQMACK", "length": 534 }, "evidence": [ { "id": "RGD:1307985", "url": "https://alliancegenome.org/gene/RGD:1307985#orthology", "database": "AGR" }, { "id": "MGI:1914238", "url": "https://alliancegenome.org/gene/MGI:1914238#orthology", "database": "AGR" }, { "id": "HGNC:18449", "url": "https://alliancegenome.org/gene/HGNC:18449#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q95R35-1", "protein_name": "Crystallomitin S-Lap4", "gene_name": "S-Lap4", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNKLRNVLKSVVQRRLPVSHLIQIRTACGGESKSSKGLVVGVYQKENDNDPKLTPAGEKVNDRLHGKLQEMICQSKITGHLGRGKIFNNIDPEFRSMAVVGVGLEGIGFNELEMLDEGMENVRVAAGIGARSLQEIGVSEVFVDGMDYAEQAAEGAVLAVWRYCDMNSKRKPPHIPKLELYESPDYEGWTRGVFKAEAQNLARRMCDTPACCMTPTLFAQATVDALCPCGITVEIRTMEWIEQQRLHSFLMIAKGSCEPPVLMEITYCGTNPEDKPILFLGKGITFNSGAMNLRKCRGMEEYRACMSGAASCVAMMRCVAALALPINVCCIIPLCENMPSGMACKPGDVVTLMNHKSMAVRNLDKAGVVVMADPLLYGQSTYKPRLVVDVATLGSGVKKAFGGGATGIFSNSHYIWKQFQSAGALTGDRVWRLPLWNYYRKQITDEMGYDLSNDGRGLANSCLAAAVLHELVPCVDWAHLDTRGTGLLTKYGLVPYLTAKYMTGRPTRTLAQFLYQMACPANQK", "length": 524 }, "evidence": [ { "id": "RGD:1307985", "url": "https://alliancegenome.org/gene/RGD:1307985#orthology", "database": "AGR" }, { "id": "MGI:1914238", "url": "https://alliancegenome.org/gene/MGI:1914238#orthology", "database": "AGR" }, { "id": "HGNC:18449", "url": "https://alliancegenome.org/gene/HGNC:18449#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q961W5-1", "protein_name": "Crystallomitin S-Lap3", "gene_name": "S-Lap3", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRGQLLLKGPALARSLSRCRVSAVPQIGSVRHVTAGCAAGDTVKGGKGIVLGLYEKESGKGPRLTPAGEKFDDRVQGKLSELVCETKLTGRLGRGKVFNNVDSEFRSICVVGVGLEGIAFNELEMLDEGMENVRIAAGIGARSLQSIGCSEVHVDNMDYAEQAAEGAALAIWRYEENLAKKYRSTIPKLELHGSPDVESWTRGLFKAEAQNLARRLCDAPANCMTPTIVAQAAVDSLCPCGITVEVRTMEWIEQQHLNSFLMIAKGSCEPPVLLEVAYCGTAPEDKPILLVGQGITFNSGGINLRPCKGMDEFRGDLTGAACILAAMRAAAALSLPINITAVIPLCENLPSGMSCKPGDVVTLLNSKSLAVRNISRTGVVVISDPMLYGQITYKPRLVVDVGSMCKGVKKAVGGGATGIWSNSHYIWKQFQRAGSLTGDRLWRFPLWRYYKDRVAEHLSFDLLNDGEGYASSCLAAAVLHELVPCSDWAHLDTYGTGLLSTYGLIPYLTAGRMTGRPTRTLVQFLYQIACPEQPK", "length": 535 }, "evidence": [ { "id": "RGD:1307985", "url": "https://alliancegenome.org/gene/RGD:1307985#orthology", "database": "AGR" }, { "id": "MGI:1914238", "url": "https://alliancegenome.org/gene/MGI:1914238#orthology", "database": "AGR" }, { "id": "HGNC:18449", "url": "https://alliancegenome.org/gene/HGNC:18449#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9CPY7-1", "protein_name": "Cytosol aminopeptidase", "gene_name": "Lap3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MYLLPLPAAARVALRRLGVRGLWDRGLSTADMTKGLVLGIYAKDKDDDLPQFTSAGESFNKLVSGKLREMLNISGPPLKAGKTRTFYGLHQDFPSVVVVGLGKRSAGVDDQENWHEGKENIRAAVAAGCRQVQDLELPSVEVDPCGDAQAAAEGAVLGLYEYDDLKQKKKVAVSAKLHGSGDLEAWEKGVLFASGQNLARHLMESPANEMTPTRFAEIIEKNLKSASSKTKVHIRPKSWIEEQEMGSFLSVAKGSEEPPVFLEIHYMGSPNATEAPLVFVGKGITFDSGGISIKASANMDLMRADMGGAATICSAIVSAAKLNLPINIIGLAPLCENMPSGKANKPGDVVRARNGKTIQVDNTDAEGRLILADALCYAHTFNPKVIINAATLTGAMDVALGSGATGVFTNSSWLWNKLFEASVETGDRVWRMPLFEHYTRQVIDCQLADVNNLGKYRSAGACTAAAFLREFVTHTKWAHLDIAGVMTNKDEIPYLRKGMSGRPTRTLIEFLLRFSKDSS", "length": 519 }, "evidence": [ { "id": "RGD:1307985", "url": "https://alliancegenome.org/gene/RGD:1307985#orthology", "database": "AGR" }, { "id": "MGI:1914238", "url": "https://alliancegenome.org/gene/MGI:1914238#orthology", "database": "AGR" }, { "id": "HGNC:18449", "url": "https://alliancegenome.org/gene/HGNC:18449#orthology", "database": "AGR" }, { "id": "FB:FBgn0052351", "url": "https://alliancegenome.org/gene/FB:FBgn0052351#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VSM6-1", "protein_name": "Crystallomitin S-Lap1", "gene_name": "S-Lap1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFGKTRQLLFSVCIRSPVCRRYVPKFIKRSYASQAVNQMLLLQQMDICADQPSRALVIGVYADEEDKNDAGILTPAGWRYNLQKTNGRLIEVLRMSGPMPKRGEARLLFAVEPERIPYYSVVAVVGLGKECLGYNPYEVLDEQKEAIRRSVAAACRILAELDTDRIEVENCGHAESAAEGAALGIWLYQELRDPKTRIFVPAIDLYATKDEVCDIEGWRIGLQKAAAQNLTRQLQEMPSNLLTPTAFAQNVVEVLCKSGVNVEVKVEGWAESQSMHAFLAVGKASCEPPIFLELSYYGTCAEERPIVLVGQGITYDAGGLCLKKKKELFNMRGDMTGAAVVVATCRAVAGLRLPVNIRGLIPLCENVVGCNSFRPGDMVKSMNGKTIEVQCTDHEDVLVLADALLYAQNFCPKCIIDIGTCSGYMRQSLDEAACGVFTNSEILWQQIKHASMHTGDRVWRFPLWNFYSKAVRAGGRSDVQNYGIGRGGRPCKAAAFLREFVPCGQWMHIDATNVMVTNGIDFEYLRRGMAGRPTRTLIEFIAQTICKDTAPKMGK", "length": 555 }, "evidence": [ { "id": "RGD:1307985", "url": "https://alliancegenome.org/gene/RGD:1307985#orthology", "database": "AGR" }, { "id": "MGI:1914238", "url": "https://alliancegenome.org/gene/MGI:1914238#orthology", "database": "AGR" }, { "id": "HGNC:18449", "url": "https://alliancegenome.org/gene/HGNC:18449#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VSM7", "url": "https://www.uniprot.org/uniprotkb/Q9VSM7" } ], "pmid": "" }, { "name": "major mitochondrial derivative", "id": "GO:0016008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016008", "evidence": [ { "database": "UniProtKB", "id": "Q9VSM7", "url": "https://www.uniprot.org/uniprotkb/Q9VSM7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9VSM7", "url": "https://www.uniprot.org/uniprotkb/Q9VSM7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "Q9VSM7", "url": "https://www.uniprot.org/uniprotkb/Q9VSM7" } ], "pmid": "" }, { "name": "manganese ion binding", "id": "GO:0030145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030145", "evidence": [ { "database": "UniProtKB", "id": "Q9VSM7", "url": "https://www.uniprot.org/uniprotkb/Q9VSM7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 226, "end_pos": 228, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q9VSM7-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 552, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q9VSM7-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q9VSM7" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 226, "end_pos": 228 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VSM8-1", "uniprot_ac": "Q9VSM8", "uniprot_id": "Q9VSM8_DROME", "mass": { "chemical_mass": 45869.0, "monoisotopic_mass": 45869.0 }, "refseq": { "ac": "NP_648245", "name": "GTPase activating protein, SECIS-dependent read-through", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648245" }, "gene_names": [ { "name": "GAPsec", "type": "recommended", "evidence": [ { "id": "Q9VSM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSM8" } ] }, { "name": "BEST:LD24460", "type": "synonym", "evidence": [ { "id": "NP_648245", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648245" }, { "id": "Q9VSM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSM8" } ] }, { "name": "CG5978", "type": "synonym", "evidence": [ { "id": "NP_648245", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648245" }, { "id": "Q9VSM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSM8" } ] }, { "name": "Dmel\\CG5978", "type": "synonym", "evidence": [ { "id": "NP_648245", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648245" }, { "id": "Q9VSM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSM8" } ] }, { "name": "Dmel_CG5978", "type": "synonym", "evidence": [ { "id": "Q9VSM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSM8" } ] }, { "name": "GAPsec", "type": "synonym", "evidence": [ { "id": "NP_648245", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648245" } ] }, { "name": "dGAPsec", "type": "synonym", "evidence": [ { "id": "NP_648245", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648245" }, { "id": "Q9VSM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSM8" } ] } ], "protein_names": [ { "name": "TBC1 domain family member 13", "type": "recommended", "evidence": [ { "id": "Q9VSM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSM8/entry#names_and_taxonomy" } ] }, { "name": "CG5978-PA", "type": "synonym", "evidence": [ { "id": "NP_648245", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648245" } ] }, { "name": "GAPsec-PA", "type": "synonym", "evidence": [ { "id": "NP_648245", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648245" } ] }, { "name": "GTPase activating protein, SECIS-dependent read-through", "type": "synonym", "evidence": [ { "id": "NP_648245", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648245" } ] } ], "function": [ { "annotation": "Acts as a GTPase-activating protein for RAB35. Together with RAB35 may be involved in regulation of insulin-induced glucose transporter SLC2A4/GLUT4 translocation to the plasma membrane in adipocytes.", "evidence": [ { "database": "UniProtKB", "id": "Q9VSM8", "url": "https://www.uniprot.org/uniprotkb/Q9VSM8#function" }, { "database": "UniProtKB", "id": "ARBA00059763", "url": "https://www.uniprot.org/uniprotkb/ARBA00059763#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VSM8", "url": "https://www.uniprot.org/uniprotkb/Q9VSM8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "GAPsec", "url": "https://www.uniprot.org/uniprotkb/Q9VSM8", "locus": { "chromosome": "3L", "start_pos": 8622039, "end_pos": 8623901, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0035916", "url": "https://www.ensemblgenomes.org/id/FBgn0035916" } ] } } ], "crossref": [ { "id": "FB:FBgn0035916", "url": "https://alliancegenome.org/gene/FB:FBgn0035916", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0035916", "url": "https://bgee.org/?page=gene&gene_id=FBgn0035916", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0035916", "url": "https://flybase.org/reports/FBgn0035916", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "38987", "url": "https://www.ncbi.nlm.nih.gov/gene/38987", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000195", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000195", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG5978", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG5978", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TEFPCEE", "url": "https://omabrowser.org/oma/group/TEFPCEE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VSM8", "url": "https://www.orthodb.org/?gene=Q9VSM8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22957", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22957", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22957:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22957:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00566", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00566", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-8854214", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8854214", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_648245", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648245", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VSM8", "url": "https://www.uniprot.org/uniprotkb/Q9VSM8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VSM8-1", "url": "https://www.uniprot.org/uniprotkb/Q9VSM8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSIFKARVKEFEDVLAGPQDLIDLKQLRKLAFNGVPDVQSFRALSWKLLLGYLGPRRSSWTTTLAQKRALYKQFIEELVLPPGHSSNRASVDGGDGDKVDSGGVGLQDHPLSEGPESAWNTFFNDNEFLLQIDKDVRRLCPDISFFQQPTDYPCEIVVHSKGEHGRRLHERVVPAVLSSANVERKGLGMTKINLITKRSVENYAAMEEGQEAHWEVVQRILFIYAKLNPGQGYVQGMNEIVGPIYYVMASDPDLTYRAHAEADCFFCFTALMSEIRDFFIKTLDDAEGGIKFMMARLSNMLKSKDLSIYELLRSQELHPQYYSFRWLTLLLSQEFPLPDVLRIWDSVFADEQRFDFLIKICCSMILIQREAILENDFASNVKLLQNYPPIDINVVIAHAGSLA", "length": 403, "header": "tr|Q9VSM8-1|Q9VSM8_DROME Isoform 1 of TBC1 domain family member 13 OS=Drosophila melanogaster OX=7227 GN=GAPsec PE=4 SV=1 CANONICAL=Q9VSM8-1" }, "isoforms": [ { "isoform_ac": "Q9VSM8-1", "url": "https://www.uniprot.org/uniprotkb/Q9VSM8/entry#Q9VSM8-1", "sequence": { "sequence": "MSIFKARVKEFEDVLAGPQDLIDLKQLRKLAFNGVPDVQSFRALSWKLLLGYLGPRRSSWTTTLAQKRALYKQFIEELVLPPGHSSNRASVDGGDGDKVDSGGVGLQDHPLSEGPESAWNTFFNDNEFLLQIDKDVRRLCPDISFFQQPTDYPCEIVVHSKGEHGRRLHERVVPAVLSSANVERKGLGMTKINLITKRSVENYAAMEEGQEAHWEVVQRILFIYAKLNPGQGYVQGMNEIVGPIYYVMASDPDLTYRAHAEADCFFCFTALMSEIRDFFIKTLDDAEGGIKFMMARLSNMLKSKDLSIYELLRSQELHPQYYSFRWLTLLLSQEFPLPDVLRIWDSVFADEQRFDFLIKICCSMILIQREAILENDFASNVKLLQNYPPIDINVVIAHAGSLA", "length": 403, "header": "tr|Q9VSM8-1|Q9VSM8_DROME Isoform 1 of TBC1 domain family member 13 OS=Drosophila melanogaster OX=7227 GN=GAPsec PE=4 SV=1 CANONICAL=Q9VSM8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VSM8", "url": "https://www.uniprot.org/uniprotkb/Q9VSM8" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VSM8", "url": "https://www.uniprot.org/uniprotkb/Q9VSM8" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VSM8", "url": "https://www.uniprot.org/uniprotkb/Q9VSM8" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VSM8", "url": "https://www.uniprot.org/uniprotkb/Q9VSM8" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VSM8", "url": "https://www.uniprot.org/uniprotkb/Q9VSM8" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VSM8", "url": "https://www.uniprot.org/uniprotkb/Q9VSM8" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VSM8", "url": "https://www.uniprot.org/uniprotkb/Q9VSM8" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VSM8", "url": "https://www.uniprot.org/uniprotkb/Q9VSM8" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VSM8", "url": "https://www.uniprot.org/uniprotkb/Q9VSM8" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VSM8", "url": "https://www.uniprot.org/uniprotkb/Q9VSM8" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VSM8", "url": "https://www.uniprot.org/uniprotkb/Q9VSM8" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG5978", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG5978", "resource": "KEGG Pathway" }, { "id": "R-DME-8854214", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8854214", "resource": "Reactome", "description": "TBC/RABGAPs" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A481BAP3-1", "protein_name": "TBC1 domain family member 13", "gene_name": "TBC1D13", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSLHKSRIADFQDVLKEPTIALEKLRELSFSGIPCEGGLRCLCWKILLNYLPLERASWTAILAKQRELYAQFLREMIIQPGIAKANMGVSREDVTFEDHPLNPNPDSRWNTYFKDNEVLLQIDKDVRRLCPDISFFQRATEYPCLLILDPQNEFETLRKRVEQTTLKSQTVARNRSGVTNMSSPNKNSASSSVSKYEVLPNGCEAHWEVVERILFIYAKLNPGIAYVQGMNEIVGPLYYTFATDPSSEWKEHAEADTFFCFTNLMAEIRDNFIKSLDDSQCGITYKMEKVYSTLKDKDVELYLKLQEQNIKPQFFAFRWLTLLLSQEFLLPDVIRIWDSLFADDNRFDFLLLVCCAMLILIREQLLEGDFTVNMRLLQDYPITDVCQILQKAKELQDSQ", "length": 400 }, "evidence": [ { "id": "Q9VSM8", "url": 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"https://alliancegenome.org/gene/RGD:1591937#orthology", "database": "AGR" }, { "id": "FB:FBgn0035916", "url": "https://alliancegenome.org/gene/FB:FBgn0035916#orthology", "database": "AGR" }, { "id": "Q9VSM8", "url": "https://omabrowser.org/oma/group/Q9VSM8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MXD4-1", "protein_name": "TBC1 domain family member 13", "gene_name": "TBC1D13", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSSLHKSRIADFQDVLKEPTIALEKLRELSFSGIPCEGGLRCLCWKILLNYLPLERASWTSILAKQRELYSQFLREMIIQPGIAKANMGVSREDVTFEDHPLNPNPDSRWNTYFRDNEVLLQIDKDVRRLCPDISFFQRATEYPCLLILDPQNEFETLRKRVEQTTLKSQTVARNRSGVTNMSSPQKNSAPSMNEYVVLPNGCEAHWEVVERILFIYAKLNPGIAYVQGMNEIVGPLYYTFATDPNSEWREHAEADTFFCFTNLMAEIRDNFIKSLDDSQCGITYKMEKVYSTLKDKDMELYLKLQEQNIKPQFFAFRWLTLLLSQEFVLPDVIRIWDSLFADSNRFDFLLLVCCAMLILIREQLLEGDFTVNMRLLQDYPITDVCQVLQKAKELQDSQ", "length": 399 }, "evidence": [ { "id": "Q9VSM8", "url": "https://omabrowser.org/oma/group/Q9VSM8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3IJA9-1", "protein_name": "TBC1 domain family member 13", "gene_name": "Tbc1d13", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSSLHKSRIADFQDVLKEPSIVLEKLRELSFSGIPCEGGLRCLCWKILLNYLPLERASWTSILAKQRGLYSQFLREMIIQPGIAKANMGVSREDVTFEDHPLNPNPDSRWNTYFKDNEVLLQIDKDVRRLCPDISFFQRATEYPCLLILDPQNEFETLRKRVEQTTLKSQTVARNRSGVTNMSSPHKNNAPPALNEYEVLPNGCEAHWEVVERILFIYAKLNPGIAYVQGMNEIVGPLYYTFATDPNSEWKEHAEADTFFCFTNLMAEIRDNFIKSLDDSQCGITYKMEKVYSTLKDKDVELYLKLQEQNIKPQFFAFRWLTLLLSQEFLLPDVIRIWDSLFADDNRFDFLLLVCCAMLILIREQLLEGDFTVNMRLLQDYPITDVCQILQKAKELQDSK", "length": 400 }, "evidence": [ { "id": "Q9VSM8", "url": "https://omabrowser.org/oma/group/Q9VSM8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8R3D1-1", "protein_name": "TBC1 domain family member 13", "gene_name": "Tbc1d13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLHKSRIADFQDVLKEPSIVLEKLRELSFSGIPCEGGLRCLCWKILLNYLPLERASWTSILAKQRGLYSQFLREMIIQPGIAKANMGVFREDVTFEDHPLNPNPDSRWNTYFKDNEVLLQIDKDVRRLCPDISFFQRATEYPCLLILDPQNEFETLRKRVEQTTLKSQTVARNRSGVTNMSSPHKNSAPSALNEYEVLPNGCEAHWEVVERILFIYAKLNPGIAYVQGMNEIVGPLYYTFATDPNSEWKEHAEADTFFCFTNLMAEIRDNFIKSLDDSQCGITYKMEKVYSTLKDKDVELYLKLQEQSIKPQFFAFRWLTLLLSQEFLLPDVIRIWDSLFADGNRFDFLLLVCCAMLILIREQLLEGDFTVNMRLLQDYPITDVCQILQKAKELQDSK", "length": 400 }, "evidence": [ { "id": "HGNC:25571", "url": "https://alliancegenome.org/gene/HGNC:25571#orthology", "database": "AGR" }, { "id": "MGI:2385326", "url": "https://alliancegenome.org/gene/MGI:2385326#orthology", "database": "AGR" }, { "id": "RGD:1591937", "url": "https://alliancegenome.org/gene/RGD:1591937#orthology", "database": "AGR" }, { "id": "FB:FBgn0035916", "url": "https://alliancegenome.org/gene/FB:FBgn0035916#orthology", "database": "AGR" }, { "id": "Q9VSM8", "url": "https://omabrowser.org/oma/group/Q9VSM8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NVG8-1", "protein_name": "TBC1 domain family member 13", "gene_name": "TBC1D13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSLHKSRIADFQDVLKEPSIALEKLRELSFSGIPCEGGLRCLCWKILLNYLPLERASWTSILAKQRELYAQFLREMIIQPGIAKANMGVSREDVTFEDHPLNPNPDSRWNTYFKDNEVLLQIDKDVRRLCPDISFFQRATDYPCLLILDPQNEFETLRKRVEQTTLKSQTVARNRSGVTNMSSPHKNSVPSSLNEYEVLPNGCEAHWEVVERILFIYAKLNPGIAYVQGMNEIVGPLYYTFATDPNSEWKEHAEADTFFCFTNLMAEIRDNFIKSLDDSQCGITYKMEKVYSTLKDKDVELYLKLQEQNIKPQFFAFRWLTLLLSQEFLLPDVIRIWDSLFADDNRFDFLLLVCCAMLMLIREQLLEGDFTVNMRLLQDYPITDVCQILQKAKELQDSK", "length": 400 }, "evidence": [ { "id": "HGNC:25571", "url": "https://alliancegenome.org/gene/HGNC:25571#orthology", "database": "AGR" }, { "id": "MGI:2385326", "url": "https://alliancegenome.org/gene/MGI:2385326#orthology", "database": "AGR" }, { "id": "RGD:1591937", "url": "https://alliancegenome.org/gene/RGD:1591937#orthology", "database": "AGR" }, { "id": "FB:FBgn0035916", "url": "https://alliancegenome.org/gene/FB:FBgn0035916#orthology", "database": "AGR" }, { "id": "Q9VSM8", "url": "https://omabrowser.org/oma/group/Q9VSM8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9SVN9-1", "protein_name": "Ypt/Rab-GAP domain of gyp1p superfamily protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAKKGIPEWLNSSLWSSSPPIDDRHLRNPAATSITPPSPPIVERPPFSSSPSAISTAPAPPLPVRPPSKSEINDLQNGSGNDGAGIETPAVSSVEDVSRKAQVVAELSKKVIDLKELRKIASQGLPDDAGIRSIVWKLLLDYLSPDRSLWSSELAKKRSQYKQFKEELLMNPSEVTRKMDKSKGGDSNDPKIESPGALSRSEITHEDHPLSLGTTSLWNNFFKDTEVLEQIERDVMRTHPDMHFFSGDSAVAKSNQDALKNILTIFAKLNPGIRYVQGMNEILAPIFYIFKNDPDKGNAAYAESDAFFCFVELMSGFRDNFCQQLDNSVVGIRYTITRLSLLLKHHDEELWRHLEVTTKINPQFYAFRWITLLLTQEFNFVESLHIWDTLLSDPEGPQETLLRICCAMLILVRRRLLAGDFTSNLKLLQNYPPTNISHMLYVADKLRTK", "length": 449 }, "evidence": [ { "id": "Q9VSM8", "url": "https://omabrowser.org/oma/group/Q9VSM8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "Q9VSM8", "url": "https://www.uniprot.org/uniprotkb/Q9VSM8" } ], "pmid": "" }, { "name": "GTPase binding", "id": "GO:0051020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051020", "evidence": [ { "database": "UniProtKB", "id": "Q9VSM8", "url": "https://www.uniprot.org/uniprotkb/Q9VSM8" } ], "pmid": "" }, { "name": "translation elongation factor binding", "id": "GO:0061770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061770", "evidence": [ { "database": "UniProtKB", "id": "Q9VSM8", "url": "https://www.uniprot.org/uniprotkb/Q9VSM8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VSM8", "url": "https://www.uniprot.org/uniprotkb/Q9VSM8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VSM8", "url": "https://www.uniprot.org/uniprotkb/Q9VSM8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "Q9VSM8", "url": "https://www.uniprot.org/uniprotkb/Q9VSM8" } ], "pmid": "" }, { "name": "translational readthrough", "id": "GO:0006451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006451", "evidence": [ { "database": "UniProtKB", "id": "Q9VSM8", "url": "https://www.uniprot.org/uniprotkb/Q9VSM8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VSM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSM8" }, { "id": "PS50086", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50086" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rab-GAP TBC", "eco_id": "ECO_0000259", "start_pos": 36, "end_pos": 351, "start_aa": "Pro", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], 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Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VSS3", "url": "https://www.uniprot.org/uniprotkb/Q9VSS3" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VSS3", "url": "https://www.uniprot.org/uniprotkb/Q9VSS3" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VSS3", "url": "https://www.uniprot.org/uniprotkb/Q9VSS3" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VSS3", "url": "https://www.uniprot.org/uniprotkb/Q9VSS3" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VSS3", "url": "https://www.uniprot.org/uniprotkb/Q9VSS3" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VSS3", "url": "https://www.uniprot.org/uniprotkb/Q9VSS3" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VSS3", "url": "https://www.uniprot.org/uniprotkb/Q9VSS3" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi 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L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VST0", "url": "https://www.uniprot.org/uniprotkb/Q9VST0" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VST0", "url": "https://www.uniprot.org/uniprotkb/Q9VST0" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VST0", "url": "https://www.uniprot.org/uniprotkb/Q9VST0" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VST0", "url": "https://www.uniprot.org/uniprotkb/Q9VST0" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VST0", "url": "https://www.uniprot.org/uniprotkb/Q9VST0" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VST0", "url": "https://www.uniprot.org/uniprotkb/Q9VST0" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VST0", "url": "https://www.uniprot.org/uniprotkb/Q9VST0" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VST0", "url": "https://www.uniprot.org/uniprotkb/Q9VST0" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VST0", "url": "https://www.uniprot.org/uniprotkb/Q9VST0" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VST0", "url": "https://www.uniprot.org/uniprotkb/Q9VST0" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VST0", "url": "https://www.uniprot.org/uniprotkb/Q9VST0" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG5093", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG5093", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZJK7-1", "protein_name": "T-box transcription factor TBX6", "gene_name": "Tbx6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYHPRELYPSLGTGYRLGHPQPGADSTFPPALTEGYRYPDLDTSKLDCFLSGIEAAPHTLAAPPPLPLLPSALGPETAPPPPEALHSLPGVSLSLENQELWKEFSAVGTEMIITKAGRRMFPACRVSVTGLDPEARYLFLLDVVPVDGARYRWQGQHWEPSGKAEPRLPDRVYIHPDSPATGAHWMRQPVSFHRVKLTNSTLDPHGHLILHSMHKYQPRIHLVRATQLCSQHWGGVASFRFPETTFISVTAYQNPRITQLKIAANPFAKGFRENGRNCKRERDARVKRKLRGPEPVATEACGSGDTPGGPCDSTLGGDIRDSDPEPAPTPQEAASASAPPCGGPSAEAYLLHPAAFHGAPSHLPARTPSFPEAPDPGRPAPYSAAFLELQPGPGSSAYQTTPSVTPFAPHFIQGAPFPLPYPGPGGYLDMGSKQMY", "length": 436 }, "evidence": [ { "id": "HGNC:11605", "url": "https://alliancegenome.org/gene/HGNC:11605#orthology", "database": "AGR" }, { "id": "MGI:102539", "url": "https://alliancegenome.org/gene/MGI:102539#orthology", "database": "AGR" }, { "id": "RGD:1307716", "url": "https://alliancegenome.org/gene/RGD:1307716#orthology", "database": "AGR" }, { "id": "FB:FBgn0035954", "url": "https://alliancegenome.org/gene/FB:FBgn0035954#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O95947-1", "protein_name": "T-box transcription factor TBX6", "gene_name": "TBX6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MYHPRELYPSLGAGYRLGPAQPGADSSFPPALAEGYRYPELDTPKLDCFLSGMEAAPRTLAAHPPLPLLPPAMGTEPAPSAPEALHSLPGVSLSLENRELWKEFSSVGTEMIITKAGRRMFPACRVSVTGLDPEARYLFLLDVIPVDGARYRWQGRRWEPSGKAEPRLPDRVYIHPDSPATGAHWMRQPVSFHRVKLTNSTLDPHGHLILHSMHKYQPRIHLVRAAQLCSQHWGGMASFRFPETTFISVTAYQNPQITQLKIAANPFAKGFRENGRNCKRERDARVKRKLRGPEPAATEAYGSGDTPGGPCDSTLGGDIRESDPEQAPAPGEATAAPAPLCGGPSAEAYLLHPAAFHGAPSHLPTRSPSFPEAPDSGRSAPYSAAFLELPHGSGGSGYPAAPPAVPFAPHFLQGGPFPLPYTAPGGYLDVGSKPMY", "length": 436 }, "evidence": [ { "id": "HGNC:11605", "url": "https://alliancegenome.org/gene/HGNC:11605#orthology", "database": "AGR" }, { "id": "MGI:102539", "url": "https://alliancegenome.org/gene/MGI:102539#orthology", "database": "AGR" }, { "id": "RGD:1307716", "url": "https://alliancegenome.org/gene/RGD:1307716#orthology", "database": "AGR" }, { "id": "FB:FBgn0035954", "url": "https://alliancegenome.org/gene/FB:FBgn0035954#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P70327-1", "protein_name": "T-box transcription factor TBX6", "gene_name": "Tbx6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MYHPRELYPSLGTGYRLGHPQPGADSTFPPALTEGYRYPDLDTSKLDCFLSGIEAAPHTLAAAAPLPLLPSALGPETAPPPPEALHSLPGVSLSLENQELWKEFSAVGTEMIITKAGRRMFPACRVSVTGLDPEARYLFLLDVVPVDGARYRWQGQHWEPSGKAEPRLPDRVYIHPDSPATGAHWMRQPVSFHRVKLTNSTLDPHGHLILHSMHKYQPRIHLVRATQLCSQHWGGVASFRFPETTFISVTAYQNPRITQLKIAANPFAKGFRENGRNCKRERDARVKRKLRGPEPVATEACGSGDTPGGPCDSTLGGDIRDSDPEQAPTPQEAASASAPPCGGPSAEAYLLHPAAFHGAPSHLPARTPSFAEAPDPGRPAPYSAAFLDLQPGPGGSAYQAAPSVPSFAPHFIQGGPFPLPYPGPGGYLDMGSKPMY", "length": 436 }, "evidence": [ { "id": "HGNC:11605", "url": "https://alliancegenome.org/gene/HGNC:11605#orthology", "database": "AGR" }, { "id": "MGI:102539", "url": "https://alliancegenome.org/gene/MGI:102539#orthology", "database": "AGR" }, { "id": "RGD:1307716", "url": "https://alliancegenome.org/gene/RGD:1307716#orthology", "database": "AGR" }, { "id": "FB:FBgn0035954", "url": "https://alliancegenome.org/gene/FB:FBgn0035954#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P79742-1", "protein_name": "T-box transcription factor TBX6L", "gene_name": "tbx6l", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNHLANNYGYYPQDCRTQYSRMNSAEAELTSLPVHVSLQDRELWDKFSSIGTEMLITKSGRRMFPSCKVTVTGLNPKVKYVVIMDMVPFDNHKYKWNKDCWEVNGSSDPHLPNRFFIHPDSPAPGQKWMQYPISFHKLKLTNNTLNSNGLVVLHSMHKYQPRLHIVQSPDPCTPHNPGAYLRFTFPEAAFIAVTAYQNQEITKLKIDNNPFAKGFRDNGLNRKRFRDKGTQEMQDTDRQVKLDLTANECAAGMSQMVEDVDVSVSSSVDCRDTQNSSSVSLNPFISAFTNPSSAGGAAAHQTHTLLSLSNRHFSSPRESNLNSVCAALPVSQLSTGHTSFSRLNPQETHHNSRPKIQLQPPHPSLQCHDLDVRLPLPPKLSRVQLSESALRNLEMSPLSDCANPRPLTNILNRSCFRASTPSGKLLPNPPQPEQFLRGSEREIYPAVQEYTDQQFTLNSQTEHRPHMRPLTEY", "length": 473 }, "evidence": [ { "id": "HGNC:11605", "url": "https://alliancegenome.org/gene/HGNC:11605#orthology", "database": "AGR" }, { "id": "MGI:102539", "url": "https://alliancegenome.org/gene/MGI:102539#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8JIS6-1", "protein_name": "T-box transcription factor TBX6", "gene_name": "tbx6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLGVEMYPGLALGPQRLSDCYYRDRDVPLYPSTCEMAARALPPALLKPHANTDSPATPQDSVRMELENAGLWKQFSTVGTEMIVTKKGRRMFPQLRVKLSGLNPSLRYILLLDIVPVDSSRYRFQDNSWQVVGGAEARLPDRVFIHPDSPATGEHWQNRTISFHRAKLTNNTLDAQGYIILHSLHRYQPRVHVIEARDVLMWGRTQHSFTFPETQFITVTAYQNNKITELKINSNPFAKGFRENGMNCKKQREARLKRKITSSQEECLDIESCDPCDSTELLPQSVDLPSSALTIMNTALPITDSGFHTEVSSHPDQTDSDQTLVLEQAFLTSEMPSSMESQQQTTSETNVNNALMDETGQMMDLSGYTSSFPTPQLSSHTSVPQSSSMYSVVSSTQSSDLELPQASSISSPHSMPAYSSIPSAEYPGVNSSTAMPASTTSLSDSYPSISHSTSSHLLQSSSYHSLLPTDQSQDNLSPHTPTNPPFQSIPACQGTRLTIDSGQNQVDDGGLSSANATTPAVPNPTQTAFPFPPVQPNNDPDPTSPSCQSLPQSALPYQQVSQCNQIPTPSDPNTTPTAFPFPPSEQSTPNSIMVSSNPNTTAFPFPPVQQQLNLSTSGPSSFPVSQSSGLNAIPNPVHPTTGSFSFPSTSAIHQGPMQSVPNTLHPSTAYTFPSSLPKHTGPLPNPAPTSYPFPTPIPPGPHPLQSLTLPSSCSIPNTSQIQSTFPQSYHNPSFSHIPPQMANHSQITSQSFPPLQTSSAPQLLSQSSTHPQCPPPSNAYPAVAPTEIGTFPQLNSAAPYLPDVVLHPSILPSLDPSLSSSAPPSLYNPFPSYSLRLCQDPRSSLHLPLRHIYRQPQHAHGQGSYFDLGGRTVF", "length": 874 }, "evidence": [ { "id": "HGNC:11605", "url": "https://alliancegenome.org/gene/HGNC:11605#orthology", "database": "AGR" }, { "id": "MGI:102539", "url": "https://alliancegenome.org/gene/MGI:102539#orthology", "database": "AGR" }, { "id": "RGD:1307716", "url": "https://alliancegenome.org/gene/RGD:1307716#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9U8L5-1", "protein_name": "Dorsocross1, isoform A", "gene_name": "Doc1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLSMQELMDMRMQQQLAHEIYRQQIMQRIPDPFPSMLPFNMPHQQPHMMLPSRPTLPGVEAKLENNDLWQQFHKIGTEMIITKSGRRMFPSMRVSLSGLEEEASYCVLLEMVPIGDCRYKFSGSQWVPAGGAEPQSPQRMYLHPDSPATGAHWQSQALLFNKVKLTNNTLDSSGHIVLASMHKYQPRLHIIRSSELTQLPWAPQQAFVFPETEFVAVTAYQNDRITKLKIDNNPFAKGFRESGQSRCKRKLNSSGNSTLESEDDGSSVSSCDSPQAKRQRQDFEQDSTGSVSPAYYGATHPVANPMSPYLRHHLSYGPSGAAGLPPSIAAAYFGGVPPQILPMPPATYAPTVAPVSPVASQPVGSSTPTTSPRPSTSTKRNSFSISAILAY", "length": 391 }, "evidence": [ { "id": "HGNC:11605", "url": "https://alliancegenome.org/gene/HGNC:11605#orthology", "database": "AGR" }, { "id": "MGI:102539", "url": "https://alliancegenome.org/gene/MGI:102539#orthology", "database": "AGR" }, { "id": "RGD:1307716", "url": "https://alliancegenome.org/gene/RGD:1307716#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VST2-1", "protein_name": "Dorsocross2", "gene_name": "Doc2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MITMNELVDLRMQQHIAHEIYRQQIMQRIPDPFPPMLPIPMPRHVIMPPRVTLPGVEMTLQNDDLWKQFHQIGTEMIITKSGRRMFPSMRLSVSGLEDESNYCVLLEMVPIGDCRYKFSGSQWVPAGGAEPQSPQRMYLHPDSPATGAHWQAQPILFNKVKLTNNTLDNSGHIVLASMHKYQPRLHVIRTADLAQIPWAPQQAFVFAETEFVAVTAYQNDRITKLKIDNNPFAKGFRETGQSRCKRKMSSSPTGEDQDQSPSLSHSQSQSESDMSPTKGGGETAGGTSSIGDSDGPQIKRLRSNGSACSLSSSLDDQSVPGASSLALGSPPPHLHSHSHPHPLQARSASSVFMQHFQQNMQSLLRPSLVDLACTYFGRPHEYGGAIQASPMYPPAAMLQAGLGPHPGLNLPPGVSGADLISDESGAEELELDVGSETSTLEQSTQEQPLEQPSTRSKGFSISAILGGGS", "length": 469 }, "evidence": [ { "id": "HGNC:11605", "url": "https://alliancegenome.org/gene/HGNC:11605#orthology", "database": "AGR" }, { "id": "MGI:102539", "url": "https://alliancegenome.org/gene/MGI:102539#orthology", "database": "AGR" }, { "id": "RGD:1307716", "url": "https://alliancegenome.org/gene/RGD:1307716#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "cell fate 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"name": "cardiocyte differentiation", "id": "GO:0035051", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035051", "evidence": [ { "database": "UniProtKB", "id": "Q9VST0", "url": "https://www.uniprot.org/uniprotkb/Q9VST0" } ], "pmid": "" }, { "name": "imaginal disc fusion, thorax closure", "id": "GO:0046529", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046529", "evidence": [ { "database": "UniProtKB", "id": "Q9VST0", "url": "https://www.uniprot.org/uniprotkb/Q9VST0" } ], "pmid": "" }, { "name": "anterior Malpighian tubule development", "id": "GO:0061327", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061327", "evidence": [ { "database": "UniProtKB", "id": "Q9VST0", "url": "https://www.uniprot.org/uniprotkb/Q9VST0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VST0", "url": 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"MENHFSATSRPSATPRMCTTASAVGAAASAAAAAGNNNNNSNSSSNNNATTGNNLSVSTAAGGATNAAATAQPIQVIPMPMLPTGAAQIIIGQQPQGQATATGLQPQLIPLQANQIMLQAAQQQPQMQVMQLPDGQTIFYQTPTIAALDPNAAANAAAAMAAQPTPHYLNINGQLVQINPAPSANQAAPTAGQQIIMVPQTAMAAVNAAAANAGVGAGVGTVVTQQQQQQHQQVQSQTQNQQQQQQQQTVAAVAASAAVNNISADVSTSTTGTNTNSEDESSKGEADEEPLYVNAKQYKRILIRRQARAKLESRIPKERCKYLHESRHRHAMNRARGEGGRFHSAQEKGDQDSSGPEGGSMPMASSGGVTLSRGTARAPPKLIAPHQTPSITITAIKSE", "length": 399, "header": "tr|Q9VSY9-1|Q9VSY9_DROME Isoform 1 of Nuclear transcription factor Y subunit OS=Drosophila melanogaster OX=7227 GN=Nf-YA PE=1 SV=1 CANONICAL=Q9VSY9-1" }, "isoforms": [ { "isoform_ac": "Q9VSY9-1", "url": "https://www.uniprot.org/uniprotkb/Q9VSY9/entry#Q9VSY9-1", "sequence": { "sequence": 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Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VSY9", "url": "https://www.uniprot.org/uniprotkb/Q9VSY9" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VSY9", "url": "https://www.uniprot.org/uniprotkb/Q9VSY9" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VSY9", "url": "https://www.uniprot.org/uniprotkb/Q9VSY9" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VSY9", "url": "https://www.uniprot.org/uniprotkb/Q9VSY9" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VSY9", "url": "https://www.uniprot.org/uniprotkb/Q9VSY9" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VSY9", "url": "https://www.uniprot.org/uniprotkb/Q9VSY9" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VSY9", "url": "https://www.uniprot.org/uniprotkb/Q9VSY9" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VSY9", "url": "https://www.uniprot.org/uniprotkb/Q9VSY9" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VSY9", "url": "https://www.uniprot.org/uniprotkb/Q9VSY9" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VSY9", "url": "https://www.uniprot.org/uniprotkb/Q9VSY9" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VSY9", "url": "https://www.uniprot.org/uniprotkb/Q9VSY9" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG3891", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3891", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M3B723-1", "protein_name": "Nuclear transcription factor Y subunit", "gene_name": "nfya", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEQYTTTTTTSGEQIVVQASGGQIQQQGTVTAVQLQTEPQVGQTAAQQVLQVVQGQPLMVQVSGGQLITSSGQPIMVQAMTGGQGQTIMQVPVSGTQGLQQIQLVQPGQIQLPGGQTLQLQGQQGQTQQIIIQQPQTAVTAGQNQGQQQITVQGQQVAQTAEGQTIVYQPVNADGTILQQGMITIPAASLAGAQLVSAGSNTNTTNTGQGTVTVTLPMAGNMVNAGGMVMMVPGGSNSVPTMQRIPLPGAEMLEEEPLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGDGGRFFSPKEKEEMALQAIKVSEGLELSSHWPATSAPPLG", "length": 346 }, "evidence": [ { "id": "RGD:70976", "url": "https://alliancegenome.org/gene/RGD:70976#orthology", "database": "AGR" }, { "id": "MGI:97316", "url": "https://alliancegenome.org/gene/MGI:97316#orthology", "database": "AGR" }, { "id": "HGNC:7804", "url": 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"dme:Dmel_CG33696", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG33696", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HINSCQH", "url": "https://omabrowser.org/oma/group/HINSCQH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VT27", "url": "https://www.orthodb.org/?gene=Q9VT27", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46641", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46641", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46641:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46641:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001027122", "url": 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Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VT27", "url": "https://www.uniprot.org/uniprotkb/Q9VT27" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VT27", "url": "https://www.uniprot.org/uniprotkb/Q9VT27" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VT27", "url": "https://www.uniprot.org/uniprotkb/Q9VT27" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VT27", "url": "https://www.uniprot.org/uniprotkb/Q9VT27" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VT27", "url": "https://www.uniprot.org/uniprotkb/Q9VT27" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": 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Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VT27", "url": "https://www.uniprot.org/uniprotkb/Q9VT27" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VT27", "url": "https://www.uniprot.org/uniprotkb/Q9VT27" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi 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Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VT66", "url": "https://www.uniprot.org/uniprotkb/Q9VT66" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VT66", "url": "https://www.uniprot.org/uniprotkb/Q9VT66" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": 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"name": "vnc", "url": "https://www.uniprot.org/uniprotkb/Q9VT75", "locus": { "chromosome": "3L", "start_pos": 9974023, "end_pos": 9972312, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0263251", "url": "https://www.ensemblgenomes.org/id/FBgn0263251" } ] } } ], "crossref": [ { "id": "FB:FBgn0263251", "url": "https://alliancegenome.org/gene/FB:FBgn0263251", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0263251", "url": "https://bgee.org/?page=gene&gene_id=FBgn0263251", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "2.3.1.255", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.1.255&UniProtAcc=Q9VT75", "database": "BRENDA", "categories": [ "Enzyme and Pathway" ] }, { "id": "cd04301", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04301", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0263251", "url": "https://flybase.org/reports/FBgn0263251", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "39175", "url": "https://www.ncbi.nlm.nih.gov/gene/39175", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VT75", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VT75*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR000182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG11989", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG11989", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MSMQNAN", "url": "https://omabrowser.org/oma/group/MSMQNAN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VT75", "url": "https://www.orthodb.org/?gene=Q9VT75", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23091", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23091", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23091:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23091:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00583", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00583", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_648378", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648378", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "50496", "url": "https://www.rhea-db.org/rhea/50496", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "50500", "url": "https://www.rhea-db.org/rhea/50500", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "50504", "url": "https://www.rhea-db.org/rhea/50504", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "50508", "url": "https://www.rhea-db.org/rhea/50508", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "50512", "url": "https://www.rhea-db.org/rhea/50512", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "50516", "url": "https://www.rhea-db.org/rhea/50516", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q9VT75", "url": "https://www.uniprot.org/uniprotkb/Q9VT75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VT75-1", "url": "https://www.uniprot.org/uniprotkb/Q9VT75-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNIRCAKPEDLMTMQHCNLLCLPENYQMKYYFYHGLTWPQLSYVAVDDKGAIVGYVLAKMEEPEPNEESRHGHITSLAVKRSYRRLGLAQKLMNQASQAMVECFNAQYVSLHVRKSNRAALNLYTNALKFKIIEVEPKYYADGEDAYAMRRDLSEFADEDQAKAAKQSGEEEEKAVHRSGGHGHSHNHSGHDGHCC", "length": 196, "header": "tr|Q9VT75-1|Q9VT75_DROME Isoform 1 of N-terminal amino-acid N(alpha)-acetyltransferase NatA OS=Drosophila melanogaster OX=7227 GN=vnc PE=1 SV=1 CANONICAL=Q9VT75-1" }, "isoforms": [ { "isoform_ac": "Q9VT75-1", "url": "https://www.uniprot.org/uniprotkb/Q9VT75/entry#Q9VT75-1", "sequence": { "sequence": "MNIRCAKPEDLMTMQHCNLLCLPENYQMKYYFYHGLTWPQLSYVAVDDKGAIVGYVLAKMEEPEPNEESRHGHITSLAVKRSYRRLGLAQKLMNQASQAMVECFNAQYVSLHVRKSNRAALNLYTNALKFKIIEVEPKYYADGEDAYAMRRDLSEFADEDQAKAAKQSGEEEEKAVHRSGGHGHSHNHSGHDGHCC", "length": 196, "header": "tr|Q9VT75-1|Q9VT75_DROME Isoform 1 of N-terminal amino-acid N(alpha)-acetyltransferase NatA OS=Drosophila melanogaster OX=7227 GN=vnc PE=1 SV=1 CANONICAL=Q9VT75-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VT75", "url": "https://www.uniprot.org/uniprotkb/Q9VT75" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VT75", "url": "https://www.uniprot.org/uniprotkb/Q9VT75" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VT75", "url": "https://www.uniprot.org/uniprotkb/Q9VT75" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VT75", "url": "https://www.uniprot.org/uniprotkb/Q9VT75" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VT75", "url": "https://www.uniprot.org/uniprotkb/Q9VT75" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VT75", "url": "https://www.uniprot.org/uniprotkb/Q9VT75" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VT75", "url": "https://www.uniprot.org/uniprotkb/Q9VT75" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VT75", "url": "https://www.uniprot.org/uniprotkb/Q9VT75" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VT75", "url": "https://www.uniprot.org/uniprotkb/Q9VT75" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VT75", "url": "https://www.uniprot.org/uniprotkb/Q9VT75" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VT75", "url": "https://www.uniprot.org/uniprotkb/Q9VT75" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG11989", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG11989", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K7P4-1", "protein_name": "N-terminal amino-acid N(alpha)-acetyltransferase NatA", "gene_name": "Txnl4a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSYMLPHLHNGWQVDQAILSEEDRVVVIRFGHDWDPTCMKMDEVLYSIAEKIFLILCESCLDIPAVLKQTVLVSLVLCGILSDSRGLTGLPAASMNIRRARPDDLMNMQHCNLLCLPENYQMKYYFYHGLSWPQLSYIAEDEDGKIVGYVLAKMEEDPDDVPHGHITSLAVKRSHRRLGLAQKLMDQASRAMIENFSAKYVSLHVRKSNRAALHLYSNTLNFQVSEVEPKYYADGEDAYAMKRDLSQMADELRRQLVLKKGRYVVLGSKENQGSTLPGSEEACQQENLAVGDSGSDGKDSTDVQDSLQTLGSAS", "length": 314 }, "evidence": [ { "id": "HGNC:28125", "url": "https://alliancegenome.org/gene/HGNC:28125#orthology", "database": "AGR" }, { "id": "FB:FBgn0263251", "url": "https://alliancegenome.org/gene/FB:FBgn0263251#orthology", "database": "AGR" }, { "id": "RGD:6492735", "url": "https://alliancegenome.org/gene/RGD:6492735#orthology", "database": "AGR" }, { "id": "RGD:1560212", "url": "https://alliancegenome.org/gene/RGD:1560212#orthology", "database": "AGR" }, { "id": "SGD:S000001055", "url": "https://alliancegenome.org/gene/SGD:S000001055#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A9B2-1", "protein_name": "N-terminal amino-acid N(alpha)-acetyltransferase NatA", "gene_name": "Naa10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGSSPGTGAFCTPPRNPACVPEDLMNMQHCNLLCLPENYQMKYYFYHGLSWPQLSYIAEDENGKIVGYVLAKMEEDPDDVPHGHITSLAVKRSHRRLGLAQKLMDQASRAMIENFNAKYVSLHVRKSNRAALHLYSNTLNFQISEVEPKYYADGEDAYAMKRDLTQMADEPAPGPGSSCLLSGDLGPVSFHPLPSGLPAAAEAAPGAEGKGQAHGAVGHGEQGGEQRQRASELRRGLS", "length": 238 }, "evidence": [ { "id": "MGI:1915255", "url": "https://alliancegenome.org/gene/MGI:1915255#orthology", "database": "AGR" }, { "id": "HGNC:18704", "url": "https://alliancegenome.org/gene/HGNC:18704#orthology", "database": "AGR" }, { "id": "FB:FBgn0263251", "url": "https://alliancegenome.org/gene/FB:FBgn0263251#orthology", "database": "AGR" }, { "id": "RGD:1565315", "url": "https://alliancegenome.org/gene/RGD:1565315#orthology", "database": "AGR" }, { "id": "SGD:S000001055", "url": "https://alliancegenome.org/gene/SGD:S000001055#orthology", "database": "AGR" }, { "id": "Q9VT75", "url": "https://omabrowser.org/oma/group/Q9VT75/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P07347-1", "protein_name": "N-terminal acetyltransferase A complex catalytic subunit ARD1", "gene_name": "ARD1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MPINIRRATINDIICMQNANLHNLPENYMMKYYMYHILSWPEASFVATTTTLDCEDSDEQDENDKLELTLDGTNDGRTIKLDPTYLAPGEKLVGYVLVKMNDDPDQQNEPPNGHITSLSVMRTYRRMGIAENLMRQALFALREVHQAEYVSLHVRQSNRAALHLYRDTLAFEVLSIEKSYYQDGEDAYAMKKVLKLEELQISNFTHRRLKENEEKLEDDLESDLLEDIIKQGVNDIIV", "length": 238 }, "evidence": [ { "id": "RGD:1564723", "url": "https://alliancegenome.org/gene/RGD:1564723#orthology", "database": "AGR" }, { "id": "MGI:1915255", "url": "https://alliancegenome.org/gene/MGI:1915255#orthology", "database": "AGR" }, { "id": "MGI:2141314", "url": "https://alliancegenome.org/gene/MGI:2141314#orthology", "database": "AGR" }, { "id": "HGNC:18704", "url": "https://alliancegenome.org/gene/HGNC:18704#orthology", "database": "AGR" }, { "id": "HGNC:28125", "url": "https://alliancegenome.org/gene/HGNC:28125#orthology", "database": "AGR" }, { "id": "FB:FBgn0263251", "url": "https://alliancegenome.org/gene/FB:FBgn0263251#orthology", "database": "AGR" }, { "id": "RGD:6492735", "url": "https://alliancegenome.org/gene/RGD:6492735#orthology", "database": "AGR" }, { "id": "RGD:1565315", "url": "https://alliancegenome.org/gene/RGD:1565315#orthology", "database": "AGR" }, { "id": "RGD:1560212", "url": "https://alliancegenome.org/gene/RGD:1560212#orthology", "database": "AGR" }, { "id": "SGD:S000001055", "url": "https://alliancegenome.org/gene/SGD:S000001055#orthology", "database": "AGR" }, { "id": "Q9VT75", "url": "https://omabrowser.org/oma/group/Q9VT75/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P36416-1", "protein_name": "N-terminal acetyltransferase complex ARD1 subunit homolog", "gene_name": "natA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVSIRPCQIGDLMSMQNANLTCLPENYQMKYYLYHFLTWPQTSFVAEDDKGNVVGYVLAKIDENEPKRGHITSLAVLRSQRKLGIATKLMKQAEVALLEVYDADCVSLHVRKSNRAAFSLYHEVLKFKIDEIEKEYYGDKEDAYSMVLYLKPEVEEEKEREKQLEKINKAAKESIEAAKRANEEPKPVSNVIHGKKKNVKKIE", "length": 203 }, "evidence": [ { "id": "Q9VT75", "url": "https://omabrowser.org/oma/group/Q9VT75/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P41227-1", "protein_name": "N-alpha-acetyltransferase 10", "gene_name": "NAA10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNIRNARPEDLMNMQHCNLLCLPENYQMKYYFYHGLSWPQLSYIAEDENGKIVGYVLAKMEEDPDDVPHGHITSLAVKRSHRRLGLAQKLMDQASRAMIENFNAKYVSLHVRKSNRAALHLYSNTLNFQISEVEPKYYADGEDAYAMKRDLTQMADELRRHLELKEKGRHVVLGAIENKVESKGNSPPSSGEACREEKGLAAEDSGGDSKDLSEVSETTESTDVKDSSEASDSAS", "length": 235 }, "evidence": [ { "id": "MGI:1915255", "url": "https://alliancegenome.org/gene/MGI:1915255#orthology", "database": "AGR" }, { "id": "HGNC:18704", "url": "https://alliancegenome.org/gene/HGNC:18704#orthology", "database": "AGR" }, { "id": "FB:FBgn0263251", "url": "https://alliancegenome.org/gene/FB:FBgn0263251#orthology", "database": "AGR" }, { "id": "RGD:1565315", "url": "https://alliancegenome.org/gene/RGD:1565315#orthology", "database": "AGR" }, { "id": "SGD:S000001055", "url": "https://alliancegenome.org/gene/SGD:S000001055#orthology", "database": "AGR" }, { "id": "Q9VT75", "url": "https://omabrowser.org/oma/group/Q9VT75/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P83876-1", "protein_name": "Thioredoxin-like protein 4A", "gene_name": "TXNL4A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSYMLPHLHNGWQVDQAILSEEDRVVVIRFGHDWDPTCMKMDEVLYSIAEKVKNFAVIYLVDITEVPDFNKMYELYDPCTVMFFFRNKHIMIDLGTGNNNKINWAMEDKQEMVDIIETVYRGARKGRGLVVSPKDYSTKYRY", "length": 142 }, "evidence": [ { "id": "RGD:6492735", "url": "https://alliancegenome.org/gene/RGD:6492735#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P83877-1", "protein_name": "Thioredoxin-like protein 4A", "gene_name": "Txnl4a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYMLPHLHNGWQVDQAILSEEDRVVVIRFGHDWDPTCMKMDEVLYSIAEKVKNFAVIYLVDITEVPDFNKMYELYDPCTVMFFFRNKHIMIDLGTGNNNKINWAMEDKQEMVDIIETVYRGARKGRGLVVSPKDYSTKYRY", "length": 142 }, "evidence": [ { "id": "HGNC:28125", "url": "https://alliancegenome.org/gene/HGNC:28125#orthology", "database": "AGR" }, { "id": "RGD:6492735", "url": "https://alliancegenome.org/gene/RGD:6492735#orthology", "database": "AGR" }, { "id": "RGD:1560212", "url": "https://alliancegenome.org/gene/RGD:1560212#orthology", "database": "AGR" }, { "id": "SGD:S000001055", "url": "https://alliancegenome.org/gene/SGD:S000001055#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q2KI14-1", "protein_name": "N-alpha-acetyltransferase 10", "gene_name": "NAA10", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNIRNARPEDLMNMQHCNLLCLPENYQMKYYFYHGLSWPQLSYIAEDENGKIVGYVLAKMEEDPDDVPHGHITSLAVKRSHRRLGLAQKLMDQASRAMIENFNAKYVSLHVRKSNRAALHLYSNTLNFQISEVEPKYYADGEDAYAMKRDLTQMADELRRHLELKEKGRHVVLGSIENKMEGKGNSLPSSGEACREEKGLVAEDSGGDSKDLSEVSETTESTDVKDSSEASDSAS", "length": 235 }, "evidence": [ { "id": "Q9VT75", "url": "https://omabrowser.org/oma/group/Q9VT75/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3UX61-1", "protein_name": "N-alpha-acetyltransferase 11", "gene_name": "Naa11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNIRNARPDDLMNMQHCNLLCLPENYQMKYYFYHGLSWPQLSYIAEDEDGKIVGYVLAKMEEDPDDVPHGHITSLAVKRSHRRLGLAQKLMDQASRAMIENFGAKYVSLHVRKSNRAALHLYSNTLNFQVSEVEPKYYADGEDAYAMKRDLSQMTDELRRQLVLKKNRYVVLGSEETQGGTLPDAGEACLPKNPTSKDSGSSDSTDVQDSSEDLDSIS", "length": 218 }, "evidence": [ { "id": "RGD:1564723", "url": "https://alliancegenome.org/gene/RGD:1564723#orthology", "database": "AGR" }, { "id": "MGI:2141314", "url": "https://alliancegenome.org/gene/MGI:2141314#orthology", "database": "AGR" }, { "id": "HGNC:28125", "url": "https://alliancegenome.org/gene/HGNC:28125#orthology", "database": "AGR" }, { "id": "FB:FBgn0263251", "url": "https://alliancegenome.org/gene/FB:FBgn0263251#orthology", "database": "AGR" }, { "id": "SGD:S000001055", "url": "https://alliancegenome.org/gene/SGD:S000001055#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q4V8K3-1", "protein_name": "N-alpha-acetyltransferase 11", "gene_name": "Naa11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNIRNARPEDLMNMQHCNLLCLPENYQMKYYFYHGLSWPQLSYIAEDEDGKIVGYVLAKMEEDPDDVPHGHITSLAVKRSHRRLGLAQKLMDQASRAMIENFSAKYVSLHVRKSNRAALHLYSNTLNFQVSEVEPKYYADGEDAYAMKRDLAQMADELRRQLVLKKSRYVVLGSEENQEAQDSTLPDAEEACQPENPAGKGSEACQPENPAGKGSEACQPENPAGKDTGSHSTDVQDSSEYLDSTS", "length": 246 }, "evidence": [ { "id": "RGD:1564723", "url": "https://alliancegenome.org/gene/RGD:1564723#orthology", "database": "AGR" }, { "id": "MGI:2141314", "url": "https://alliancegenome.org/gene/MGI:2141314#orthology", "database": "AGR" }, { "id": "HGNC:28125", "url": "https://alliancegenome.org/gene/HGNC:28125#orthology", "database": "AGR" }, { "id": "FB:FBgn0263251", "url": "https://alliancegenome.org/gene/FB:FBgn0263251#orthology", "database": "AGR" }, { "id": "SGD:S000001055", "url": "https://alliancegenome.org/gene/SGD:S000001055#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9BSU3-1", "protein_name": "N-alpha-acetyltransferase 11", "gene_name": "NAA11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNIRNAQPDDLMNMQHCNLLCLPENYQMKYYLYHGLSWPQLSYIAEDEDGKIVGYVLAKMEEEPDDVPHGHITSLAVKRSHRRLGLAQKLMDQASRAMIENFNAKYVSLHVRKSNRPALHLYSNTLNFQISEVEPKYYADGEDAYAMKRDLSQMADELRRQMDLKKGGYVVLGSRENQETQGSTLSDSEEACQQKNPATEESGSDSKEPKESVESTNVQDSSESSDSTS", "length": 229 }, "evidence": [ { "id": "RGD:1564723", "url": "https://alliancegenome.org/gene/RGD:1564723#orthology", "database": "AGR" }, { "id": "MGI:2141314", "url": "https://alliancegenome.org/gene/MGI:2141314#orthology", "database": "AGR" }, { "id": "HGNC:28125", "url": "https://alliancegenome.org/gene/HGNC:28125#orthology", "database": "AGR" }, { "id": "FB:FBgn0263251", "url": "https://alliancegenome.org/gene/FB:FBgn0263251#orthology", "database": "AGR" }, { "id": "RGD:6492735", "url": "https://alliancegenome.org/gene/RGD:6492735#orthology", "database": "AGR" }, { "id": "RGD:1560212", "url": "https://alliancegenome.org/gene/RGD:1560212#orthology", "database": "AGR" }, { "id": "SGD:S000001055", "url": "https://alliancegenome.org/gene/SGD:S000001055#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9FKI4-1", "protein_name": "N-terminal acetyltransferase A complex catalytic subunit NAA10", "gene_name": "NAA10", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVCIRRATVDDLLAMQACNLMCLPENYQMKYYLYHILSWPQLLYVAEDYNGRIVGYVLAKMEEESNECHGHITSLAVLRTHRKLGLATKLMTAAQAAMEQVYEAEYVSLHVRRSNRAAFNLYTETLGYKINDVEAKYYADGEDAYDMRKNLKGKQNHHHAHGHHHHHGGGCCSGDAKVVETAQAVDGKAVSK", "length": 192 }, "evidence": [ { "id": "Q9VT75", "url": "https://omabrowser.org/oma/group/Q9VT75/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9QY36-1", "protein_name": "N-alpha-acetyltransferase 10", "gene_name": "Naa10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNIRNARPEDLMNMQHCNLLCLPENYQMKYYFYHGLSWPQLSYIAEDENGKIVGYVLAKMEEDPDDVPHGHITSLAVKRSHRRLGLAQKLMDQASRAMIENFNAKYVSLHVRKSNRAALHLYSNTLNFQISEVEPKYYADGEDAYAMKRDLTQMADELRRHLELKEKGKHMVLAALENKAENKGNVLLSSGEACREEKGLAAEDSGGDSKDLSEVSETTESTDVKDSSEASDSAS", "length": 235 }, "evidence": [ { "id": "MGI:1915255", "url": "https://alliancegenome.org/gene/MGI:1915255#orthology", "database": "AGR" }, { "id": "HGNC:18704", "url": "https://alliancegenome.org/gene/HGNC:18704#orthology", "database": "AGR" }, { "id": "FB:FBgn0263251", "url": "https://alliancegenome.org/gene/FB:FBgn0263251#orthology", "database": "AGR" }, { "id": "RGD:1565315", "url": "https://alliancegenome.org/gene/RGD:1565315#orthology", "database": "AGR" }, { "id": "SGD:S000001055", "url": "https://alliancegenome.org/gene/SGD:S000001055#orthology", "database": "AGR" }, { "id": "Q9VT75", "url": "https://omabrowser.org/oma/group/Q9VT75/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "oogenesis", "id": "GO:0048477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048477", "evidence": [ { "database": "UniProtKB", "id": "Q9VT75", "url": "https://www.uniprot.org/uniprotkb/Q9VT75" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "NatA complex", "id": "GO:0031415", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031415", "evidence": [ { "database": "UniProtKB", "id": "Q9VT75", "url": "https://www.uniprot.org/uniprotkb/Q9VT75" } ], "pmid": "" }, { "name": "protein acetyltransferase complex", "id": "GO:0031248", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031248", "evidence": [ { "database": "UniProtKB", "id": "Q9VT75", "url": "https://www.uniprot.org/uniprotkb/Q9VT75" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein N-terminal-serine acetyltransferase activity", "id": "GO:1990189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990189", "evidence": [ { "database": "UniProtKB", "id": "Q9VT75", "url": "https://www.uniprot.org/uniprotkb/Q9VT75" } ], "pmid": "" }, { "name": "protein-N-terminal-glutamate acetyltransferase activity", "id": "GO:1990190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990190", "evidence": [ { "database": "UniProtKB", "id": "Q9VT75", "url": "https://www.uniprot.org/uniprotkb/Q9VT75" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 187, "end_pos": 189, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "50496", "name": "", "equation": "N-terminal glycyl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetylglycyl-[protein] + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VT75-1" ], "evidence": [ { "id": "50496", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/50496" } ] }, { "id": "50500", "name": "", "equation": "N-terminal L-alanyl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-alanyl-[protein] + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VT75-1" ], "evidence": [ { "id": "50500", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/50500" } ] }, { "id": "50504", "name": "", "equation": "N-terminal L-seryl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-seryl-[protein] + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VT75-1" ], "evidence": [ { "id": "50504", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/50504" } ] }, { "id": "50508", "name": "", "equation": "N-terminal L-valyl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-valyl-[protein] + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VT75-1" ], "evidence": [ { "id": "50508", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/50508" } ] }, { "id": "50512", "name": "", "equation": "N-terminal L-cysteinyl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-cysteinyl-[protein] + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VT75-1" ], "evidence": [ { "id": "50512", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/50512" } ] }, { "id": "50516", "name": "", "equation": "N-terminal L-threonyl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-threonyl-[protein] + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VT75-1" ], "evidence": [ { "id": "50516", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/50516" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "Q9VT75", "gene_name": "vnc", "activity": [ { "ec_number": "2.3.1.255", "activity": "N-terminal L-seryl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-seryl-[protein] + CoA + H(+).", "evidence": [ { "id": "Q9VT75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VT75" } ] }, { "ec_number": "2.3.1.255", "activity": "", "evidence": [ { "id": "Q9VT75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VT75" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VT75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VT75" }, { "id": "PS51186", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51186" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "N-acetyltransferase", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 154, "start_aa": "Met", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.1.255", "ec_name": "N-terminal L-seryl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-seryl-[protein] + CoA + H(+).", "evidence": [ { "id": "2.3.1.255", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.255" }, { "id": "2.3.1.255", "database": "BRENDA Enzymes", "url": 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Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina 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Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VT82", "url": "https://www.uniprot.org/uniprotkb/Q9VT82" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VT82", "url": "https://www.uniprot.org/uniprotkb/Q9VT82" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VT82", "url": "https://www.uniprot.org/uniprotkb/Q9VT82" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VT82", "url": "https://www.uniprot.org/uniprotkb/Q9VT82" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VT82", "url": "https://www.uniprot.org/uniprotkb/Q9VT82" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VT82", "url": "https://www.uniprot.org/uniprotkb/Q9VT82" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi 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"sequence": "MDCKAPGLLETPSESELTHCSISALDNIPIQEEECPSELELSKTFDKLERMRERVLYLKSLLIHPVQVNKVECPPESDQMRLDIEQSSSDNDELRVVQQDTVRALQQIIDVNRQLKETTDSLTGLDEKARKNIRCIRKLSKRLLEVPKWKEELKHNTGLCLERYNDLDISRGNYLDYSDNFVRPIQTNMKFCFASKAPLICNKQDYNDLVSALSKSRKTLLKCHGELLKYTQKVDEALTLKNFDTMELPSISELSLLLDKSTQVTKRRSSIEKERRSFKFAWAAPLAKQEKYTPAVDISD", "length": 300, "header": "tr|Q9VT87-1|Q9VT87_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG8065 PE=4 SV=2 CANONICAL=Q9VT87-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VT87", "url": "https://www.uniprot.org/uniprotkb/Q9VT87" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VT87", "url": "https://www.uniprot.org/uniprotkb/Q9VT87" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VT87", "url": "https://www.uniprot.org/uniprotkb/Q9VT87" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VT87", "url": "https://www.uniprot.org/uniprotkb/Q9VT87" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VT87", "url": "https://www.uniprot.org/uniprotkb/Q9VT87" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VT87", "url": "https://www.uniprot.org/uniprotkb/Q9VT87" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VT87", "url": "https://www.uniprot.org/uniprotkb/Q9VT87" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VT87", "url": "https://www.uniprot.org/uniprotkb/Q9VT87" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VT87", "url": "https://www.uniprot.org/uniprotkb/Q9VT87" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VTC6", "url": "https://www.uniprot.org/uniprotkb/Q9VTC6" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": 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melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VTC6", "url": "https://www.uniprot.org/uniprotkb/Q9VTC6" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VTC6", "url": "https://www.uniprot.org/uniprotkb/Q9VTC6" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VTC6", "url": "https://www.uniprot.org/uniprotkb/Q9VTC6" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VTC6", "url": "https://www.uniprot.org/uniprotkb/Q9VTC6" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VTC6", "url": "https://www.uniprot.org/uniprotkb/Q9VTC6" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VTC6", "url": "https://www.uniprot.org/uniprotkb/Q9VTC6" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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OS=Drosophila melanogaster OX=7227 GN=Irbp18 PE=1 SV=1 CANONICAL=Q9VTE8-1" }, "isoforms": [ { "isoform_ac": "Q9VTE8-1", "url": "https://www.uniprot.org/uniprotkb/Q9VTE8/entry#Q9VTE8-1", "sequence": { "sequence": "MPAKKRTAASTSKNSDSPLSPHTDDPAYKEKRKKNNEAVQRTREKTKKSAEERKKRIDDLRKQNDALKVQIETSEKHISTLRDLIIQGEKTEDGHRIIQEILAEPDPDPKDND", "length": 113, "header": "tr|Q9VTE8-1|Q9VTE8_DROME Isoform 1 of Inverted repeat binding protein 18 kDa, isoform B OS=Drosophila melanogaster OX=7227 GN=Irbp18 PE=1 SV=1 CANONICAL=Q9VTE8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VTE8", "url": "https://www.uniprot.org/uniprotkb/Q9VTE8" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VTE8", "url": "https://www.uniprot.org/uniprotkb/Q9VTE8" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VTE8", "url": "https://www.uniprot.org/uniprotkb/Q9VTE8" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VTE8", "url": "https://www.uniprot.org/uniprotkb/Q9VTE8" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VTE8", "url": "https://www.uniprot.org/uniprotkb/Q9VTE8" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VTE8", "url": "https://www.uniprot.org/uniprotkb/Q9VTE8" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VTE8", "url": "https://www.uniprot.org/uniprotkb/Q9VTE8" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VTE8", "url": "https://www.uniprot.org/uniprotkb/Q9VTE8" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VTE8", "url": "https://www.uniprot.org/uniprotkb/Q9VTE8" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VTG0", "url": "https://www.uniprot.org/uniprotkb/Q9VTG0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VTG0-1", "url": "https://www.uniprot.org/uniprotkb/Q9VTG0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESFAPELLWMVVIGFLIAFVLAFGIGANDVANSFGTSVGSGVLTIRQACVLATICEISGAVLIGYKVSDTMRKGILEVGLYEGAEEVLMLGCVAALASSAVWLLVATFLKLPISGTHSIVGSTIGFSLVARGVQGLKWSTLGTIVGSWFISPVLSGIVSILLFLAIRRFILRAQEPLKAGFRSLPIFYGVTFFINVISVVLDGPKLLYMDNIPTWIALTASFGLSLLVALLTQLVVVPLQRRKIAKRLRAENPVKFNFEDSVESSPSGSPKKQRRPLSLVSEGKPLPAIAEITELVSLSDNSPRTFKLAPFGLAAKNNNALGEEYKIDPQLIKKAEDLLGKASLDNTDLTITSLNFIDEQQQQQQQQQNGRKLQECFKRMQSPKEEQKSKTNSIGTDLETGSTKATNNNLQVVESGGSLDLMISSTLSPNSSKVPLIESKEALNEQEEELKRTTGGGRRTSGAEETPEISMLFSFLQILTATFGSFAHGGNDVSNAIGPLIALYMIYREGSVMQQAESPIYILIYGGIGISVGLWLWGRRVIETIGNDLTKITSSTGFTIEVGAAITVLLASKIGLPISTTHCKVGSVVFVGHVSASGRKKKSQPNDQTDKETHNEVAPMDDGSVDWHLFRNIAYAWIVTVPVTALLSAGMMYVLCAIAVDDMGGA", "length": 667, "header": "tr|Q9VTG0-1|Q9VTG0_DROME Isoform 1 of Phosphate transporter OS=Drosophila melanogaster OX=7227 GN=NaPi-III PE=3 SV=2 CANONICAL=Q9VTG0-1" }, "isoforms": [ { "isoform_ac": "Q9VTG0-1", "url": "https://www.uniprot.org/uniprotkb/Q9VTG0/entry#Q9VTG0-1", "sequence": { "sequence": "MESFAPELLWMVVIGFLIAFVLAFGIGANDVANSFGTSVGSGVLTIRQACVLATICEISGAVLIGYKVSDTMRKGILEVGLYEGAEEVLMLGCVAALASSAVWLLVATFLKLPISGTHSIVGSTIGFSLVARGVQGLKWSTLGTIVGSWFISPVLSGIVSILLFLAIRRFILRAQEPLKAGFRSLPIFYGVTFFINVISVVLDGPKLLYMDNIPTWIALTASFGLSLLVALLTQLVVVPLQRRKIAKRLRAENPVKFNFEDSVESSPSGSPKKQRRPLSLVSEGKPLPAIAEITELVSLSDNSPRTFKLAPFGLAAKNNNALGEEYKIDPQLIKKAEDLLGKASLDNTDLTITSLNFIDEQQQQQQQQQNGRKLQECFKRMQSPKEEQKSKTNSIGTDLETGSTKATNNNLQVVESGGSLDLMISSTLSPNSSKVPLIESKEALNEQEEELKRTTGGGRRTSGAEETPEISMLFSFLQILTATFGSFAHGGNDVSNAIGPLIALYMIYREGSVMQQAESPIYILIYGGIGISVGLWLWGRRVIETIGNDLTKITSSTGFTIEVGAAITVLLASKIGLPISTTHCKVGSVVFVGHVSASGRKKKSQPNDQTDKETHNEVAPMDDGSVDWHLFRNIAYAWIVTVPVTALLSAGMMYVLCAIAVDDMGGA", "length": 667, "header": "tr|Q9VTG0-1|Q9VTG0_DROME Isoform 1 of Phosphate transporter OS=Drosophila melanogaster OX=7227 GN=NaPi-III PE=3 SV=2 CANONICAL=Q9VTG0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VTG0", "url": "https://www.uniprot.org/uniprotkb/Q9VTG0" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VTG0", "url": "https://www.uniprot.org/uniprotkb/Q9VTG0" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VTG0", "url": "https://www.uniprot.org/uniprotkb/Q9VTG0" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VTG0", "url": "https://www.uniprot.org/uniprotkb/Q9VTG0" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VTG0", "url": "https://www.uniprot.org/uniprotkb/Q9VTG0" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VTG0", "url": "https://www.uniprot.org/uniprotkb/Q9VTG0" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VTG0", "url": "https://www.uniprot.org/uniprotkb/Q9VTG0" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VTG0", "url": "https://www.uniprot.org/uniprotkb/Q9VTG0" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VTG0", "url": "https://www.uniprot.org/uniprotkb/Q9VTG0" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VTG0", "url": "https://www.uniprot.org/uniprotkb/Q9VTG0" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VTG0", "url": "https://www.uniprot.org/uniprotkb/Q9VTG0" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG42575", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG42575", "resource": "KEGG Pathway" }, { "id": "R-DME-427652", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-427652", "resource": "Reactome", "description": "Sodium-coupled phosphate cotransporters" } ], "orthologs": [ { "uniprot_canonical_ac": "P38361-1", "protein_name": "Phosphate permease PHO89", "gene_name": "PHO89", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MALHQFDYIFAIAMLFAFLDAFNIGANDVANSFASSISSRSLKYWQAMVLAGLCEFLGAVLAGARVSGTIKNNIIDSSIFTNDPAVLMLTMTSALIGSSCWLTFATAIGMPVSTTHSIVGGTIGAGIAAGGANGVVWGWSGVSQIIASWFIAPILAGAIAAIVFSISRFSVLEVKSLERSIKNALLLVGVLVFATFSILTMLIVWKGSPNLHLDDLSETETAVSIVLTGAIASIVYFIFFYPFYRRKVLDQDWTLKLIDIFRGPSFYFKSTDDIPPMPEGHQLTIDYYEGRRNLGTTVSVEDEENKAASNSNDSVKNKEDIQEVDLVRTETEPETKLSTKQYWWSLLKQGPKKWPLLFWLVISHGWTQDVIHAQVNDRDMLSGDLKGMYERSKFYDNRVEYIYSVLQAITAATMSFAHGANDVANATGPLSAVYVIWKTNTIGAKSEVPVWVLAYGGVALVIGCWTYGYNIIKNLGNKMILQSPSRGFSIELAVAITTVMATQLGIPTSTTQIAVGGIVAVGLCNKDLKSVNWRMVAWCYSGWFLTLPIAGLIAGIINGIILNAPRFGVEYQMT", "length": 574 }, "evidence": [ { "id": "RGD:621079", "url": "https://alliancegenome.org/gene/RGD:621079#orthology", "database": "AGR" }, { "id": "MGI:97851", "url": "https://alliancegenome.org/gene/MGI:97851#orthology", "database": "AGR" }, { "id": "MGI:108392", "url": "https://alliancegenome.org/gene/MGI:108392#orthology", "database": "AGR" }, { "id": "HGNC:10947", "url": "https://alliancegenome.org/gene/HGNC:10947#orthology", "database": "AGR" }, { "id": "HGNC:10946", "url": "https://alliancegenome.org/gene/HGNC:10946#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-260", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-260#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-2217", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-2217#orthology", "database": "AGR" }, { "id": "FB:FBgn0260795", "url": "https://alliancegenome.org/gene/FB:FBgn0260795#orthology", "database": "AGR" }, { "id": "RGD:3699", "url": "https://alliancegenome.org/gene/RGD:3699#orthology", "database": "AGR" }, { "id": "SGD:S000000500", "url": "https://alliancegenome.org/gene/SGD:S000000500#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q08357-1", "protein_name": "Sodium-dependent phosphate transporter 2", "gene_name": "SLC20A2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAMDEYLWMVILGFIIAFILAFSVGANDVANSFGTAVGSGVVTLRQACILASIFETTGSVLLGAKVGETIRKGIIDVNLYNETVETLMAGEVSAMVGSAVWQLIASFLRLPISGTHCIVGSTIGFSLVAIGTKGVQWMELVKIVASWFISPLLSGFMSGLLFVLIRIFILKKEDPVPNGLRALPVFYAATIAINVFSIMYTGAPVLGLVLPMWAIALISFGVALLFAFFVWLFVCPWMRRKITGKLQKEGALSRVSDESLSKVQEAESPVFKELPGAKANDDSTIPLTGAAGETLGTSEGTSAGSHPRAAYGRALSMTHGSVKSPISNGTFGFDGHTRSDGHVYHTVHKDSGLYKDLLHKIHIDRGPEEKPAQESNYRLLRRNNSYTCYTAAICGLPVHATFRAADSSAPEDSEKLVGDTVSYSKKRLRYDSYSSYCNAVAEAEIEAEEGGVEMKLASELADPDQPREDPAEEEKEEKDAPEVHLLFHFLQVLTACFGSFAHGGNDVSNAIGPLVALWLIYKQGGVTQEAATPVWLLFYGGVGICTGLWVWGRRVIQTMGKDLTPITPSSGFTIELASAFTVVIASNIGLPVSTTHCKVGSVVAVGWIRSRKAVDWRLFRNIFVAWFVTVPVAGLFSAAVMALLMYGILPYV", "length": 652 }, "evidence": [ { "id": "MGI:97851", "url": "https://alliancegenome.org/gene/MGI:97851#orthology", "database": "AGR" }, { "id": "HGNC:10947", "url": "https://alliancegenome.org/gene/HGNC:10947#orthology", "database": "AGR" }, { "id": "FB:FBgn0260795", "url": "https://alliancegenome.org/gene/FB:FBgn0260795#orthology", "database": "AGR" }, { "id": "RGD:3699", "url": "https://alliancegenome.org/gene/RGD:3699#orthology", "database": "AGR" }, { "id": "SGD:S000000500", "url": "https://alliancegenome.org/gene/SGD:S000000500#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q38954-1", "protein_name": "Inorganic phosphate transporter 2-1, chloroplastic", "gene_name": "PHT2-1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MTLPYRFSSVRNHSLLLKTSHLCTPRSALGCCFSPKESPFFRKNTAQFLSPQKHTSLPLKLVCPLASFSSYADSEGEEQHHADQPIQNPHESSTVSNESDGKGNAEATGDFSGMAQAFHISSTTARAISIVIAFSALTLPIFMKSLGQGLALKTKLLSYATLLFGFYMAWNIGANDVANAMGTSVGSGALTIRQAVMTAAVLEFSGALLMGTHVTSTMQKGILMANVFQGKDMLLFAGLLSSLAAAGTWLQVASYYGWPVSTTHCIVGSMVGFGLVYGGAGAVFWSSLAKVASSWVISPILGALVSFLVYKCIRRFVYSAPNPGQAAAAAAPVAVFVGVASISSAALPLSKIFPIALSQALACGVAGAIVFDRIIRKQLGHLLAKTKSPETSQNQPKTIGFLSDIAGPTGTQLEIVYGIFGYMQVLSACFMSFAHGGNDVSNAIGPLAAALSILQNGAAAGGAEIVIPMDVLAWGGFGIVAGLTMWGYRVIATIGKKITELTPTRGFAAEFAAASVVLFASKLGLPISATHTLVGAVMGVGFARGLNSVRAETVREIVASWLVTIPVGATLAVIYTWIFTKILSFVL", "length": 587 }, "evidence": [ { "id": "Q9VTG0", "url": "https://omabrowser.org/oma/group/Q9VTG0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q61609-1", "protein_name": "Sodium-dependent phosphate transporter 1", "gene_name": "Slc20a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESTVATITSTLAAVTASAPPKYDNLWMLILGFIIAFVLAFSVGANDVANSFGTAVGSGVVTLKQACILASIFETVGSALLGAKVSETIRNGLIDVELYNETQDLLMAGSVSAMFGSAVWQLVASFLKLPISGTHCIVGATIGFSLVANGQKGVKWSELIKIVMSWFVSPLLSGIMSGILFFLVRAFILRKADPVPNGLRALPIFYACTIGINLFSIMYTGAPLLGFDKLPLWGTILISVGCAVFCALIVWFFVCPRMKRKIEREVKSSPSESPLMEKKSNLKEDHEETKMAPGDVEHRNPVSEVVCATGPLRAVVEERTVSFKLGDLEEAPERERLPMDLKEETSIDSTINGAVQLPNGNLVQFSQTVSNQINSSGHYQYHTVHKDSGLYKELLHKLHLAKVGDCMGDSGDKPLRRNNSYTSYTMAICGMPLDSFRAKEGEQKGDEMETLTWPNADTKKRIRMDSYTSYCNAVSDLHSESEMDMSVKAEMGLGDRKGSSGSLEEWYDQDKPEVSLLFQFLQILTACFGSFAHGGNDVSNAIGPLVALYLVYKQEASTKAATPIWLLLYGGVGICMGLWVWGRRVIQTMGKDLTPITPSSGFSIELASALTVVIASNIGLPISTTHCKVGSVVSVGWLRSKKAVDWRLFRNIFMAWFVTVPISGVISAAIMAVFKYIILPV", "length": 681 }, "evidence": [ { "id": "RGD:621079", "url": "https://alliancegenome.org/gene/RGD:621079#orthology", "database": "AGR" }, { "id": "MGI:108392", "url": "https://alliancegenome.org/gene/MGI:108392#orthology", "database": "AGR" }, { "id": "HGNC:10946", "url": "https://alliancegenome.org/gene/HGNC:10946#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-260", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-260#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-2217", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-2217#orthology", "database": "AGR" }, { "id": "FB:FBgn0260795", "url": "https://alliancegenome.org/gene/FB:FBgn0260795#orthology", "database": "AGR" }, { "id": "SGD:S000000500", "url": "https://alliancegenome.org/gene/SGD:S000000500#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q63488-1", "protein_name": "Sodium-dependent phosphate transporter 2", "gene_name": "Slc20a2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAMDGYLWMVILGFIIAFILAFSVGANDVANSFGTAVGSGVVTLRQACILASIFETTGSVLLGAKVGETIRKGIIDVNLYNETVETLMAGEVSAMVGSAVWQLIASFLRLPISGTHCIVGSTIGFSLVAIGPKGVQWMELVKIVASWFISPLLSGFMSGVLFILIRMFILTKEDPVPNGLQALPLFYAATIAINVFSIMYTGAPVLGLSLPIWAIALISFGVALLFAFFVWLFVCPWMKRKIAGRLEKESALSRASDESLRKVQEAESPVFKELPGAKASDDSAVPLTSLAGEAAGASEGTSAGNHPRASYGRALSMTHGSAKSPISNGTFGFEGHMRNDGHVYHTVHKDSGLYKDLLHKIHVDKGPEEKPAQENNYRLLRRNNSYTCYTAAICGMPVHATFRASDTSSAPEDSEKLVGDTVSYSKKRLRYDSYSSYCNAVAEAEIEAEEGGVEMRLASELTDPDQPHEDPAEDEKEEKDSAEVHLLFHFLQVLTACFGSFAHGGNDVSNAIGPLVALWLIYKQGGVTQEAATPVWLLFYGGVGICTGLWVWGRRVIQTMGKDLTPITPSSGFTIELASAFTVVIASNIGLPVSTTHCKVGSVVAVGWIRSRKAVDWRLFRNIFIAWFVTVPVAGLFSAAIMALLMYICGFVSSSR", "length": 656 }, "evidence": [ { "id": "MGI:97851", "url": "https://alliancegenome.org/gene/MGI:97851#orthology", "database": "AGR" }, { "id": "HGNC:10947", "url": "https://alliancegenome.org/gene/HGNC:10947#orthology", "database": "AGR" }, { "id": "FB:FBgn0260795", "url": "https://alliancegenome.org/gene/FB:FBgn0260795#orthology", "database": "AGR" }, { "id": "RGD:3699", "url": "https://alliancegenome.org/gene/RGD:3699#orthology", "database": "AGR" }, { "id": "SGD:S000000500", "url": "https://alliancegenome.org/gene/SGD:S000000500#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6NV12-1", "protein_name": "Sodium-dependent phosphate transporter 1-A", "gene_name": "slc20a1a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MESTTLASLAAVSVLAAGAQTDMSDVLWLLILGFVIAFILAFSVGANDVANSFGTAVGSGVVTLRQACILATIFETVGAMLLGAKVSETIRSGIIDVHMYNGSEAVLMAGSISAMFGSAVWQLAASFLKLPISGTHCIVGATIGFSMVARGHQGVKWLELLRIVASWFLSPLLSGIMSAVLFYFVRKFILNKDDPVPNGLRALPVFYAVTMGINLFSIMFTGAPMLGFDRIPWWGTLLISLGCAILTALVVWFIVCPRLKKKMQSKCLGPNIADTSGTQLVEKKPSSNGLMDHHPGPPRNYSPVPQTPPADSNKVAFDIGGSAETDLDKKEFDTKDQDCTHALNGSGGIVIPDLSGNQFHTVHKDSGIYKDLLHKLHLAKVGECIGEPVEKPIRRNNSYTSYTMAIYGIHGSLKDGEGGSRTGLDGEKRRSRYDSYNSYCTAVADGEAALEDAALAVGMEDEALREDVLEEDIDELEIDKPEVSTLFQFLQILTACFGSFAHGGNDVSNAIGPLVALWLIYDSASVAPSAPTPIWLLLYGGVGICTGLWIWGRRVIQTMGKDLTPITPSSGFSIELASAITVVVASNIGLPVSTTHCKVGSVVSVGWLRSRKAVDWHLFRNIFIAWFVTVPISGLISAAIMALFYYVILPLT", "length": 652 }, "evidence": [ { "id": "RGD:621079", "url": "https://alliancegenome.org/gene/RGD:621079#orthology", "database": "AGR" }, { "id": "MGI:108392", "url": "https://alliancegenome.org/gene/MGI:108392#orthology", "database": "AGR" }, { "id": "HGNC:10946", "url": "https://alliancegenome.org/gene/HGNC:10946#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-2217", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-2217#orthology", "database": "AGR" }, { "id": "FB:FBgn0260795", "url": "https://alliancegenome.org/gene/FB:FBgn0260795#orthology", "database": "AGR" }, { "id": "SGD:S000000500", "url": "https://alliancegenome.org/gene/SGD:S000000500#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6PFM1-1", "protein_name": "Sodium-dependent phosphate transporter 1-B", "gene_name": "slc20a1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVSTTLATITIMSTLVGYTTGPLTDYMWLLIVGFIIAFVLAFSVGANDVANSFGTAVGSGVVTLRQACILASIFETLGSVLLGAKVSETIRKGIIDVTMYKDIEHVLMAGSVSAMFGSAVWQLAASFLKLPISGTHCIVGATIGFSLVAKGQQGVKWLELLRIVASWFLSPLLSGVMSAVLFYFVRMFILQKKDPVPNGLRALPFFYAVTMGINLFSIMFTGAPMLGFDKLPWWGVLLISIGFGIITALIVWFAVCPRLKKKIECEVKSSSPSESPLMEKRELHEAHSPILKPVPEESSVLSSSTPTTPPLPPPEERRVTFDIGDSDDADQKDCKESDLGGAPKTAHVHFTNGPAHIPSNGYSQYHTVHKDSGLYKDLLHKLHLAKVGDCMGEGGDRPIRRNNSYTSYTMAIIGMHGDFKPKESEFRASEDGDKEKAGAQERKRIRMDSYTSYCNAVAENGTPEDLGEGEVTLEMVDEDAGSSRSSLEEDRTDADKPEVSMLFQFLQILTACFGSFAHGGNDVSNAIGPLVALWLVYESGSVISSAPTPIWLLLYGGVGICVGLWVWGRRVIQTMGRDLTPITPSSGFSIELASAVTVVVASNIGLPVSTTHCKVGSVVAVGWLRSRKAVDWRLFRNIFMAWFVTVPISGLISAAIMALFNYVIL", "length": 665 }, "evidence": [ { "id": "RGD:621079", "url": "https://alliancegenome.org/gene/RGD:621079#orthology", "database": "AGR" }, { "id": "MGI:108392", "url": "https://alliancegenome.org/gene/MGI:108392#orthology", "database": "AGR" }, { "id": "HGNC:10946", "url": "https://alliancegenome.org/gene/HGNC:10946#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-260", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-260#orthology", "database": "AGR" }, { "id": "FB:FBgn0260795", "url": "https://alliancegenome.org/gene/FB:FBgn0260795#orthology", "database": "AGR" }, { "id": "SGD:S000000500", "url": "https://alliancegenome.org/gene/SGD:S000000500#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q80UP8-1", "protein_name": "Sodium-dependent phosphate transporter 2", "gene_name": "Slc20a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAMDGYLWMVILGFIIAFILAFSVGANDVANSFGTAVGSGVVTLRQACILASIFETTGSVLLGAKVGETIRKGIIDVNLYNETVETLMAGEVSAMVGSAVWQLIASFLRLPISGTHCIVGSTIGFSLVAIGPKGVQWMELVKIVASWFISPLLSGFMSGVLFILIRMFILTKEDPVPNGLQALPLFYAATIAINVFSIMYTGAPVLGLSLPIWAIALISFGVALLFAFFVWLFVCPWMKRKIAGRLEKESALSRASDESLRKVQEAESPGFKELPGAKPSDDSAVPLTSLAGEAVGASEGTSAGNHPRASYGRALSMTHGSAKSPISNGTFGFEGHMRNDGHVYHTVHKDSGLYKDLLHKIHVDRGSEEKPTQENNYRLLRRNNSYTCYTAAICGMPVHTTFRASDTSSAPEDSEKLVGDSVSYSKKRLRYDSYSSYCNAVAEAEIEAEEGGVEMRLASELADPDRPHEDPTEEEKEEKDSAEVHLLFHFLQVLTACFGSFAHGGNDVSNAIGPLVALWLIYQQGGVTQEAATPVWLLFYGGVGICTGLWVWGRRVIQTMGKDLTPITPSSGFTIELASAFTVVIASNIGLPVSTTHCKVGSVVAVGWIRSRKAVDWRLFRNIFVAWFVTVPVAGLFSAAIMALLMYICGLFSSSR", "length": 656 }, "evidence": [ { "id": "MGI:97851", "url": "https://alliancegenome.org/gene/MGI:97851#orthology", "database": "AGR" }, { "id": "HGNC:10947", "url": "https://alliancegenome.org/gene/HGNC:10947#orthology", "database": "AGR" }, { "id": "FB:FBgn0260795", "url": "https://alliancegenome.org/gene/FB:FBgn0260795#orthology", "database": "AGR" }, { "id": "RGD:3699", "url": "https://alliancegenome.org/gene/RGD:3699#orthology", "database": "AGR" }, { "id": "SGD:S000000500", "url": "https://alliancegenome.org/gene/SGD:S000000500#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WUM9-1", "protein_name": "Sodium-dependent phosphate transporter 1", "gene_name": "SLC20A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATLITSTTAATAASGPLVDYLWMLILGFIIAFVLAFSVGANDVANSFGTAVGSGVVTLKQACILASIFETVGSVLLGAKVSETIRKGLIDVEMYNSTQGLLMAGSVSAMFGSAVWQLVASFLKLPISGTHCIVGATIGFSLVAKGQEGVKWSELIKIVMSWFVSPLLSGIMSGILFFLVRAFILHKADPVPNGLRALPVFYACTVGINLFSIMYTGAPLLGFDKLPLWGTILISVGCAVFCALIVWFFVCPRMKRKIEREIKCSPSESPLMEKKNSLKEDHEETKLSVGDIENKHPVSEVGPATVPLQAVVEERTVSFKLGDLEEAPERERLPSVDLKEETSIDSTVNGAVQLPNGNLVQFSQAVSNQINSSGHYQYHTVHKDSGLYKELLHKLHLAKVGDCMGDSGDKPLRRNNSYTSYTMAICGMPLDSFRAKEGEQKGEEMEKLTWPNADSKKRIRMDSYTSYCNAVSDLHSASEIDMSVKAEMGLGDRKGSNGSLEEWYDQDKPEVSLLFQFLQILTACFGSFAHGGNDVSNAIGPLVALYLVYDTGDVSSKVATPIWLLLYGGVGICVGLWVWGRRVIQTMGKDLTPITPSSGFSIELASALTVVIASNIGLPISTTHCKVGSVVSVGWLRSKKAVDWRLFRNIFMAWFVTVPISGVISAAIMAIFRYVILRM", "length": 679 }, "evidence": [ { "id": "RGD:621079", "url": "https://alliancegenome.org/gene/RGD:621079#orthology", "database": "AGR" }, { "id": "MGI:108392", "url": "https://alliancegenome.org/gene/MGI:108392#orthology", "database": "AGR" }, { "id": "HGNC:10946", "url": "https://alliancegenome.org/gene/HGNC:10946#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-260", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-260#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-2217", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-2217#orthology", "database": "AGR" }, { "id": "FB:FBgn0260795", "url": "https://alliancegenome.org/gene/FB:FBgn0260795#orthology", "database": "AGR" }, { "id": "SGD:S000000500", "url": "https://alliancegenome.org/gene/SGD:S000000500#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JJP0-1", "protein_name": "Sodium-dependent phosphate transporter 1", "gene_name": "Slc20a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASTLAPITSTLAAVTASAPPKYDNLWMLILGFIIAFVLAFSVGANDVANSFGTAVGSGVVTLKQACILASIFETVGSALLGAKVSETIRKGLIDVEKYNATQDLLMAGSVSAMFGSAVWQLVASFLKLPISGTHCIVGATIGFSLVAKGQEGIKWSELIKIVMSWFVSPLLSGIMSGILFFLVRAFILRKADPVPNGLRALPIFYACTIGINLFSIMYTGAPLLGFDKLPLWGTILISVGCAVFCALIVWFFVCPRMKRKIEREVKSSPSESPLMEKKNNLKDHEETKMAPGDVENRNPVSEVVCATGPLRAVVEERTVSFKLGDLEEAPERERLPMDLKEETNIDGTINGAVQLPNGNLVQFSQTVSNQINSSGHYQYHTVHKDSGLYKELLHKLHLAKVGDCMGDSGDKPLRRNNSYTSYTMAICGMPLDSFRAKEGEQKGDEMETLTWPNADTKKRIRMDSYTSYCNAVSDLHSESEMDMSVKAEMGLGDRKGSSGSLEEWYDQDKPEVSLLFQFLQILTACFGSFAHGGNDVSNAIGPLVALYLVYETRDVTTKEATPIWLLLYGGVGICMGLWVWGRRVIQTMGKDLTPITPSSGFSIELASAFTVVVASNIGLPISTTHCKVGSVVSVGWLRSKKAVDWRLFRNIFMAWFVTVPISGVISAAIMAVFKHIILPV", "length": 681 }, "evidence": [ { "id": "RGD:621079", "url": "https://alliancegenome.org/gene/RGD:621079#orthology", "database": "AGR" }, { "id": "MGI:108392", "url": "https://alliancegenome.org/gene/MGI:108392#orthology", "database": "AGR" }, { "id": "HGNC:10946", "url": "https://alliancegenome.org/gene/HGNC:10946#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-260", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-260#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-2217", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-2217#orthology", "database": "AGR" }, { "id": "FB:FBgn0260795", "url": "https://alliancegenome.org/gene/FB:FBgn0260795#orthology", "database": "AGR" }, { "id": "SGD:S000000500", "url": "https://alliancegenome.org/gene/SGD:S000000500#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VTG0", "url": "https://www.uniprot.org/uniprotkb/Q9VTG0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "phosphate transmembrane transporter activity", "id": "GO:0005315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005315", "evidence": [ { "database": "UniProtKB", "id": "Q9VTG0", "url": "https://www.uniprot.org/uniprotkb/Q9VTG0" } ], "pmid": "" }, { "name": "sodium:phosphate symporter activity", "id": "GO:0005436", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005436", "evidence": [ { "database": "UniProtKB", "id": "Q9VTG0", "url": "https://www.uniprot.org/uniprotkb/Q9VTG0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "phosphate ion transmembrane transport", "id": "GO:0035435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035435", "evidence": [ { "database": "UniProtKB", "id": "Q9VTG0", "url": "https://www.uniprot.org/uniprotkb/Q9VTG0" } ], "pmid": "" }, { "name": "sodium-dependent phosphate transport", "id": "GO:0044341", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044341", "evidence": [ { "database": "UniProtKB", "id": "Q9VTG0", "url": "https://www.uniprot.org/uniprotkb/Q9VTG0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 431, "end_pos": 433, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 431, "end_pos": 433 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VTH8-1", "uniprot_ac": "Q9VTH8", "uniprot_id": "Q9VTH8_DROME", "mass": { "chemical_mass": 48535.0, "monoisotopic_mass": 48535.0 }, "refseq": { "ac": "NP_001261709", "name": "uncharacterized protein, isoform B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261709" }, "gene_names": [ { "name": "Dmel\\CG6163", "type": "recommended", "evidence": [ { "id": "Q9VTH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTH8" } ] }, { "name": "CG6163", "type": "synonym", "evidence": [ { "id": "NP_001261709", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261709" }, { "id": "Q9VTH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTH8" } ] }, { "name": "Dmel\\CG6163", "type": "synonym", "evidence": [ { "id": "NP_001261709", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261709" } ] }, { "name": "Dmel_CG6163", "type": "synonym", "evidence": [ { "id": "Q9VTH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTH8" } ] } ], "protein_names": [ { "name": "MADF domain-containing protein", "type": "recommended", "evidence": [ { "id": "Q9VTH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTH8/entry#names_and_taxonomy" } ] }, { "name": "CG6163-PB", "type": "synonym", "evidence": [ { "id": "NP_001261709", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261709" } ] }, { "name": "uncharacterized protein, isoform B", "type": "synonym", "evidence": [ { "id": "NP_001261709", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261709" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VTH8", "url": "https://www.uniprot.org/uniprotkb/Q9VTH8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG6163", "url": "https://www.uniprot.org/uniprotkb/Q9VTH8", "locus": { "chromosome": "3L", "start_pos": 11361986, "end_pos": 11364885, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0036155", "url": "https://www.ensemblgenomes.org/id/FBgn0036155" } ] } } ], "crossref": [ { "id": "FB:FBgn0036155", "url": "https://alliancegenome.org/gene/FB:FBgn0036155", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0036155", "url": "https://bgee.org/?page=gene&gene_id=FBgn0036155", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0036155", "url": "https://flybase.org/reports/FBgn0036155", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "39274", "url": "https://www.ncbi.nlm.nih.gov/gene/39274", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VTH8", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VTH8*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR006578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039353", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039353", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG6163", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG6163", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EMILHVQ", "url": "https://omabrowser.org/oma/group/EMILHVQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VTH8", "url": "https://www.orthodb.org/?gene=Q9VTH8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12243", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12243", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12243:SF64", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12243:SF64", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10545", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10545", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001261709", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261709", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VTH8", "url": "https://www.uniprot.org/uniprotkb/Q9VTH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VTH8-1", "url": "https://www.uniprot.org/uniprotkb/Q9VTH8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPKEDPFVNRAQLLKAIKKYPEIWDSNNKLHMCRSVTSPMWTEIAEQFGGHVPTVKLQSIWSQMKYHYHNLVHRQILHKDRFNTKWEHFEPMSFMYNITVAKIVGAQSSGGSGGGTSSDAPSTATEAATVGEEPAAPVAPPPLPTATHGRGRPSGSFSWLQTATTPTAPQLPHLITQPPHSQGHGMTYTAFTGLVPPPATVASETVATPPRKLGRPSSLHNSMRGRIIDAIKTRPSLWAGRQRSEKGQGQSRTSAVWKEAAMEMGLTPTLMQTRWSIIKQRYVDELQKERHAQYSHQSFRSTWEHFDRMSFMREILLKKVDEREQTREQIQEIVSEQQHHQQTQHHPSQHLHHYRPPQPPAGLVEHAQDMPIGLVQHHHQEGHHPTLAMHHPQHSQPIRRRVKHESDLEWDPFEMILHVHGAGEPAAN", "length": 428, "header": "tr|Q9VTH8-1|Q9VTH8_DROME Isoform 1 of MADF domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG6163 PE=4 SV=1 CANONICAL=Q9VTH8-1" }, "isoforms": [ { "isoform_ac": "Q9VTH8-1", "url": "https://www.uniprot.org/uniprotkb/Q9VTH8/entry#Q9VTH8-1", "sequence": { "sequence": "MPKEDPFVNRAQLLKAIKKYPEIWDSNNKLHMCRSVTSPMWTEIAEQFGGHVPTVKLQSIWSQMKYHYHNLVHRQILHKDRFNTKWEHFEPMSFMYNITVAKIVGAQSSGGSGGGTSSDAPSTATEAATVGEEPAAPVAPPPLPTATHGRGRPSGSFSWLQTATTPTAPQLPHLITQPPHSQGHGMTYTAFTGLVPPPATVASETVATPPRKLGRPSSLHNSMRGRIIDAIKTRPSLWAGRQRSEKGQGQSRTSAVWKEAAMEMGLTPTLMQTRWSIIKQRYVDELQKERHAQYSHQSFRSTWEHFDRMSFMREILLKKVDEREQTREQIQEIVSEQQHHQQTQHHPSQHLHHYRPPQPPAGLVEHAQDMPIGLVQHHHQEGHHPTLAMHHPQHSQPIRRRVKHESDLEWDPFEMILHVHGAGEPAAN", "length": 428, "header": "tr|Q9VTH8-1|Q9VTH8_DROME Isoform 1 of MADF domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG6163 PE=4 SV=1 CANONICAL=Q9VTH8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VTH8", "url": "https://www.uniprot.org/uniprotkb/Q9VTH8" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VTH8", "url": "https://www.uniprot.org/uniprotkb/Q9VTH8" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VTH8", "url": "https://www.uniprot.org/uniprotkb/Q9VTH8" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VTH8", "url": "https://www.uniprot.org/uniprotkb/Q9VTH8" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VTH8", "url": "https://www.uniprot.org/uniprotkb/Q9VTH8" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VTH8", "url": "https://www.uniprot.org/uniprotkb/Q9VTH8" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VTH8", "url": "https://www.uniprot.org/uniprotkb/Q9VTH8" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VTH8", "url": "https://www.uniprot.org/uniprotkb/Q9VTH8" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VTH8", "url": "https://www.uniprot.org/uniprotkb/Q9VTH8" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VTH8", "url": "https://www.uniprot.org/uniprotkb/Q9VTH8" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VTH8", "url": "https://www.uniprot.org/uniprotkb/Q9VTH8" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG6163", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG6163", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VTH8", "url": "https://www.uniprot.org/uniprotkb/Q9VTH8" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "Q9VTH8", "url": "https://www.uniprot.org/uniprotkb/Q9VTH8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q9VTH8", "url": 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"type": "synonym", "evidence": [ { "id": "NP_648462", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648462" }, { "id": "Q9VTI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTI0" } ] }, { "name": "Dmel\\CG7560", "type": "synonym", "evidence": [ { "id": "NP_648462", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648462" } ] }, { "name": "Dmel_CG7560", "type": "synonym", "evidence": [ { "id": "Q9VTI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTI0" } ] }, { "name": "gh18008", "type": "synonym", "evidence": [ { "id": "NP_648462", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648462" }, { "id": "Q9VTI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTI0" } ] } ], "protein_names": [ { "name": "Methylenetetrahydrofolate reductase-like catalytic domain-containing protein", "type": "recommended", "evidence": [ { "id": "Q9VTI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTI0/entry#names_and_taxonomy" } ] }, { "name": "CG7560-PA", "type": "synonym", "evidence": [ { "id": "NP_648462", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648462" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_648462", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648462" } ] } ], "function": [], "disease": [ { "disease_id": "DOID:0050589", "recommended_name": { "id": "DOID:0050589", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050589", "name": "inflammatory bowel disease", "description": "An intestinal disease characterized by inflammation located in all parts of digestive tract." }, "synonyms": [ { "id": "MONDO:0009960", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009960", "name": "inflammatory bowel disease 1", "description": "Any inflammatory bowel disease in which the cause of the disease is a mutation in the NOD2 gene." }, { "id": "MONDO:0009960", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009960", "name": "Crohn disease-associated growth failure", "description": "" }, { "id": "MONDO:0009960", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009960", "name": "IBD1", "description": "" }, { "id": "MONDO:0009960", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009960", "name": "NOD2 inflammatory bowel disease", "description": "" }, { "id": "MONDO:0009960", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009960", "name": "inflammatory bowel disease (Crohn disease) 1", "description": "" }, { "id": "MONDO:0009960", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009960", "name": "inflammatory bowel disease 1", "description": "" }, { "id": "MONDO:0009960", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009960", "name": "inflammatory bowel disease 1, Crohn disease", "description": "" }, { "id": "MONDO:0009960", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009960", "name": "inflammatory bowel disease caused by mutation in NOD2", "description": "" }, { "id": "MONDO:0009960", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009960", "name": "inflammatory bowel disease type 1", "description": "" }, { "id": "MONDO:0009960", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009960", "name": "paediatric ulcerative colitis", "description": "" }, { "id": "MONDO:0009960", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009960", "name": "pediatric ulcerative colitis", "description": "" }, { "id": "MONDO:0009960", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009960", "name": "ulcerative colitis, paediatric", "description": "" }, { "id": "MONDO:0009960", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009960", "name": "ulcerative colitis, pediatric", "description": "" }, { "id": "MIM:266600", "resource": "MIM", "url": "https://www.omim.org/entry/266600", "name": "Inflammatory bowel disease 1", "description": "Inflammatory bowel disease 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "0050589", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050589" } ] }, { "disease_id": "DOID:0050745", "recommended_name": { "id": "DOID:0050745", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050745", "name": "diffuse large B-cell lymphoma", "description": "A large B-cell lymphoma that is consisting of medium-sized to large B cells with a diffuse growth pattern." }, "synonyms": [ { "id": "DOID:0050745", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050745", "name": "DLBCL", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "0050745", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050745" } ] }, { "disease_id": "DOID:0050830", "recommended_name": { "id": "DOID:0050830", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050830", "name": "peripheral artery disease", "description": "An artery disease that is characterized by build up of plaque in the arteries that carry blood to your head, organs, and limbs." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "0050830", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050830" } ] }, { "disease_id": "DOID:0050864", "recommended_name": { "id": "DOID:0050864", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050864", "name": "non-arteritic anterior ischemic optic neuropathy", "description": "An anterior ischemic optic neuropathy that is characterized by near-complete vision loss caused by acute ischemic damage to the optic nerve due to non-inflammatory small vessel disease." }, "synonyms": [ { "id": "DOID:0050864", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050864", "name": "non-arteritic anterior ischaemic optic neuropathy", "description": "" }, { "id": "DOID:0050864", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050864", "name": "nonarteritic anterior ischaemic optic neuropathy", "description": "" }, { "id": "DOID:0050864", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050864", "name": "nonarteritic anterior ischemic optic neuropathy", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "0050864", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050864" } ] }, { "disease_id": "DOID:0050866", "recommended_name": { "id": "DOID:0050866", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050866", "name": "oral squamous cell carcinoma", "description": "An oral cavity cancer that has_material_basis_in squamous cells." }, "synonyms": [ { "id": "DOID:0050866", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050866", "name": "mouth squamous cell carcinoma", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "0050866", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050866" } ] }, { "disease_id": "DOID:0051054", "recommended_name": { "id": "DOID:0051054", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0051054", "name": "coarctation of the aorta", "description": "A congenital heart disease that is characterized by the luminal narrowing of the thoracic aortic arch, typically located just beyond the left subclavian artery. This narrowing creates an obstruction that can lead to significant cardiovascular complications, including systemic hypertension, left ventricular hypertrophy, and eventually heart failure." }, "synonyms": [ { "id": "MONDO:0007345", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007345", "name": "aorta coarctation", "description": "Congenital narrowing of a segment of the aorta. Signs and symptoms include hypertension, muscle weakness, shortness of breath, headaches and leg cramps." }, { "id": "MONDO:0007345", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007345", "name": "aortic coarctation", "description": "" }, { "id": "MONDO:0007345", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007345", "name": "coarctation of the aorta", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "0051054", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0051054" } ] }, { "disease_id": "DOID:0051061", "recommended_name": { "id": "DOID:0051061", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0051061", "name": "stroke", "description": "A cerebrovascular disease that is characterized by disruption of blood flow to the brain resulting in damage to brain cells due to a lack of oxygen." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "0051061", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0051061" } ] }, { "disease_id": "DOID:0060770", "recommended_name": { "id": "DOID:0060770", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0060770", "name": "dextro-looped transposition of the great arteries", "description": "A congenital heart disease characterized by complete inversion of the great vessels where the aorta incorrectly arises from the right ventricle and the pulmonary artery incorrectly arises from the left ventricle." }, "synonyms": [ { "id": "DOID:0060770", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0060770", "name": "congenitally uncorrected transposition of the great vessels", "description": "" }, { "id": "DOID:0060770", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0060770", "name": "ventriculoarterial discordance with atrioventricular concordance", "description": "" }, { "id": "DOID:0060770", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0060770", "name": "D-TGA", "description": "" }, { "id": "DOID:0060770", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0060770", "name": "DTGA1", "description": "" }, { "id": "DOID:0060770", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0060770", "name": "isolated ventriculoarterial discordance", "description": "" }, { "id": "DOID:0060770", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0060770", "name": "congenitally uncorrected transposition of the great arteries", "description": "" }, { "id": "MONDO:0012128", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012128", "name": "obsolete transposition of the great arteries, dextro-looped", "description": "OBSOLETE. Any dextro-looped transposition of the great arteries in which the cause of the disease is a mutation in the MED13L gene." }, { "id": "MONDO:0012128", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012128", "name": "DTGA", "description": "" }, { "id": "MONDO:0012128", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012128", "name": "DTGA1", "description": "" }, { "id": "MONDO:0012128", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012128", "name": "MED13L dextro-looped transposition of the great arteries", "description": "" }, { "id": "MONDO:0012128", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012128", "name": "dextro-looped transposition of the great arteries 1", "description": "" }, { "id": "MONDO:0012128", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012128", "name": "dextro-looped transposition of the great arteries caused by mutation in MED13L", "description": "" }, { "id": "MONDO:0012128", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012128", "name": "dextro-looped transposition of the great arteries type 1", "description": "" }, { "id": "MONDO:0012128", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012128", "name": "transposition of the great arteries, dextro-looped type 1", "description": "" }, { "id": "MONDO:0012128", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012128", "name": "transposition of the great arteries, dextro-looped 1", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "0060770", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060770" } ] }, { "disease_id": "DOID:0070004", "recommended_name": { "id": "DOID:0070004", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070004", "name": "myeloid neoplasm", "description": "A bone marrow cancer that is formed of any one of the bone marrow cells belonging to the granulocytic (neutrophil, eosinophil, basophil), monocytic/macrophage, erythroid, megakaryocytic and mast cell lineages." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "0070004", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070004" } ] }, { "disease_id": "DOID:0080016", "recommended_name": { "id": "DOID:0080016", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080016", "name": "spina bifida", "description": "A neural tube defect that is characterized by incomplete closing of the spine and membranes around the spinal cord during early development." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "0080016", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080016" } ] }, { "disease_id": "DOID:0080074", "recommended_name": { "id": "DOID:0080074", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080074", "name": "neural tube defect", "description": "A physical disorder characterized by incomplete closure of the neural tube." }, "synonyms": [ { "id": "MONDO:0010525", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010525", "name": "neural tube defects, X-linked", "description": "" }, { "id": "MONDO:0010525", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010525", "name": "neural tube defects, X-linked", "description": "" }, { "id": "MONDO:0010525", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010525", "name": "X-linked anencephaly/spina bifida", "description": "" }, { "id": "MONDO:0010525", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010525", "name": "anencephaly and spina bifida X-linked", "description": "" }, { "id": "MONDO:0011120", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011120", "name": "neural tube defects, folate-sensitive", "description": "" }, { "id": "MONDO:0011120", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011120", "name": "neural tube defects, folate-sensitive", "description": "" }, { "id": "MONDO:0011120", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011120", "name": "NTDFS", "description": "" }, { "id": "MIM:601634", "resource": "MIM", "url": "https://www.omim.org/entry/601634", "name": "Neural tube defects, folate-sensitive", "description": "Neural tube defects, folate-sensitive" } ], "unlinked_id_list": [], "evidence": [ { "id": "0080074", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080074" } ] }, { "disease_id": "DOID:0080177", "recommended_name": { "id": "DOID:0080177", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080177", "name": "hepatic veno-occlusive disease", "description": "A hepatic vascular disease that is characterized by obstruction of some of the small veins of the liver." }, "synonyms": [ { "id": "DOID:0080177", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080177", "name": "veno-occlusive disease", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "0080177", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080177" } ] }, { "disease_id": "DOID:0080208", "recommended_name": { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "metabolic dysfunction-associated steatotic liver disease", "description": "A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and no other discernible cause with normal to no alcohol use. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol." }, "synonyms": [ { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "nonalcoholic fatty liver disease", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "non-alcoholic fatty liver disease", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "NAFLD", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "metabolic dysfunction-associated fatty liver disease", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "metabolic dysfunction-related steatotic liver disease", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "MAFLD", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "MASLD", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "metabolic-associated fatty liver disease", "description": "" }, { "id": "MONDO:0013246", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013246", "name": "fatty liver disease, nonalcoholic, susceptibility to, 2", "description": "" }, { "id": "MONDO:0013246", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013246", "name": "NAFLD2", "description": "" }, { "id": "MONDO:0013246", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013246", "name": "fatty liver disease, nonalcoholic, susceptibility to, 2", "description": "" }, { "id": "MONDO:0021105", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021105", "name": "NAFLD1", "description": "" }, { "id": "MONDO:0021105", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021105", "name": "NAFLD1", "description": "" }, { "id": "MONDO:0021105", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021105", "name": "fatty liver disease, nonalcoholic, susceptibility to, 1", "description": "" }, { "id": "MONDO:0021105", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021105", "name": "liver disease, alcoholic, susceptibility to, 1", "description": "" }, { "id": "MIM:613282", "resource": "MIM", "url": "https://www.omim.org/entry/613282", "name": "Non-alcoholic fatty liver disease 1", "description": "Non-alcoholic fatty liver disease 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "0080208", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080208" } ] }, { "disease_id": "DOID:0081267", "recommended_name": { "id": "DOID:0081267", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0081267", "name": "graft-versus-host disease", "description": "An immune system disease that is characterized by recognition by mature donor T cells, that contaminate the allogeneic bone marrow, of the recipient's tissue as foreign, causing a severe inflammatory disease characterized by rashes, diarrhea, and liver disease, and that has_material_basis_in an associated with variation in the interleukin-10 gene (IL10) on chromosome 1q32." }, "synonyms": [ { "id": "DOID:0081267", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0081267", "name": "GvHD", "description": "" }, { "id": "DOID:0081267", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0081267", "name": "graft versus host disease", "description": "" }, { "id": "MONDO:0100048", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0100048", "name": "graft-versus-host disease, susceptibility to", "description": "An inherited susceptibility or predisposition to developing graft vs. host disease." }, { "id": "MONDO:0100048", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0100048", "name": "GVHDS", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "0081267", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081267" } ] }, { "disease_id": "DOID:0111907", "recommended_name": { "id": "DOID:0111907", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111907", "name": "thrombophilia due to thrombin defect", "description": "A thrombophilia characterized by recurrent thrombophilia that has_material_basis_in heterozygous mutation in F2 on chromosome 11p11.2." }, "synonyms": [ { "id": "DOID:0111907", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111907", "name": "prothrombin thrombophilia", "description": "" }, { "id": "DOID:0111907", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111907", "name": "THPH1", "description": "" }, { "id": "DOID:0111907", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111907", "name": "prothrombin-related thrombophilia", "description": "" }, { "id": "DOID:0111907", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111907", "name": "thrombophilia due to factor 2 defect", "description": "" }, { "id": "MONDO:0008559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008559", "name": "thrombophilia due to thrombin defect", "description": "The formation of a blood clot (thrombus) in the lumen of a vein." }, { "id": "MONDO:0008559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008559", "name": "Venous thromboembolism", "description": "" }, { "id": "MONDO:0008559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008559", "name": "prothrombin thrombophilia", "description": "" }, { "id": "MONDO:0008559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008559", "name": "prothrombin-related thrombophilia", "description": "" }, { "id": "MONDO:0008559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008559", "name": "thrombophilia 1 due to thrombin defect", "description": "" }, { "id": "MONDO:0008559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008559", "name": "thrombophilia due to thrombin defect", "description": "" }, { "id": "MONDO:0008559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008559", "name": "venous thromboembolism, susceptibility to", "description": "" }, { "id": "MONDO:0008559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008559", "name": "venous thrombosis, protection against", "description": "" }, { "id": "MONDO:0008559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008559", "name": "THPH1", "description": "" }, { "id": "MONDO:0008559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008559", "name": "factor II-related thrombophilia", "description": "" }, { "id": "MONDO:0008559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008559", "name": "hyperprothrombinemia", "description": "" }, { "id": "MONDO:0008559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008559", "name": "prothrombin 20210G>A thrombophilia", "description": "" }, { "id": "MONDO:0008559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008559", "name": "prothrombin G20210A thrombophilia", "description": "" }, { "id": "MIM:188050", "resource": "MIM", "url": "https://www.omim.org/entry/188050", "name": "Thrombophilia due to thrombin defect", "description": "Thrombophilia due to thrombin defect" } ], "unlinked_id_list": [], "evidence": [ { "id": "0111907", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111907" } ] }, { "disease_id": "DOID:10024", "recommended_name": { "id": "DOID:10024", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10024", "name": "migraine with aura", "description": "A migraine characterized by migraine headache which is preceded or accompanied by a transient focal neurological phenomenon." }, "synonyms": [ { "id": "DOID:10024", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10024", "name": "classic migraine", "description": "" }, { "id": "MONDO:0012210", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012210", "name": "migraine with aura, susceptibility to, 7", "description": "" }, { "id": "MONDO:0012210", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012210", "name": "migraine with aura, susceptibility to, 7", "description": "" }, { "id": "MONDO:0012210", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012210", "name": "migraine with aura, susceptibility to, type 7", "description": "" }, { "id": "MONDO:0012331", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012331", "name": "migraine with aura, susceptibility to, 9", "description": "" }, { "id": "MONDO:0012331", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012331", "name": "migraine with aura, susceptibility to, 9", "description": "" }, { "id": "MONDO:0012331", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012331", "name": "migraine with aura, susceptibility to, type 9", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "10024", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10024" } ] }, { "disease_id": "DOID:1067", "recommended_name": { "id": "DOID:1067", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1067", "name": "open-angle glaucoma", "description": "A glaucoma characterized by optic nerve damage resulting in progressive loss of visual field and increased pressure in the eye due to trabecular blockage." }, "synonyms": [ { "id": "DOID:1067", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1067", "name": "Wide-angle glaucoma", "description": "" }, { "id": "DOID:1067", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1067", "name": "glaucoma simplex", "description": "" }, { "id": "DOID:1067", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1067", "name": "open angle glaucoma", "description": "" }, { "id": "DOID:1067", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1067", "name": "pigmentary glaucoma", "description": "" }, { "id": "MONDO:0008328", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008328", "name": "glaucoma 1, open angle, P", "description": "" }, { "id": "MONDO:0008328", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008328", "name": "glaucoma 1, open angle, P", "description": "" }, { "id": "MONDO:0008328", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008328", "name": "glaucoma 1, open angle, type P", "description": "" }, { "id": "MONDO:0008328", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008328", "name": "GLC1P", "description": "" }, { "id": "MONDO:0011222", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011222", "name": "obsolete glaucoma 1, open angle, D", "description": "" }, { "id": "MONDO:0011222", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011222", "name": "GLC1D", "description": "" }, { "id": "MONDO:0011222", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011222", "name": "glaucoma 1, open angle, D", "description": "" }, { "id": "MONDO:0011222", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011222", "name": "glaucoma 1D, primary open angle", "description": "" }, { "id": "MONDO:0011311", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011311", "name": "obsolete glaucoma 1, open angle, F", "description": "" }, { "id": "MONDO:0011311", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011311", "name": "glaucoma 1, open angle, F", "description": "" }, { "id": "MONDO:0011311", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011311", "name": "glaucoma 1, open angle, type F", "description": "" }, { "id": "MONDO:0011311", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011311", "name": "GLC1F", "description": "" }, { "id": "MONDO:0011704", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011704", "name": "obsolete glaucoma 1, open angle, B", "description": "" }, { "id": "MONDO:0011704", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011704", "name": "GLC1B", "description": "" }, { "id": "MONDO:0011704", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011704", "name": "glaucoma 1, open angle, B", "description": "" }, { "id": "MONDO:0011704", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011704", "name": "glaucoma 1B, primary open angle, adult onset", "description": "" }, { "id": "MONDO:0012101", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012101", "name": "glaucoma 1, open angle, J", "description": "" }, { "id": "MONDO:0012101", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012101", "name": "GLC1J", "description": "" }, { "id": "MONDO:0012101", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012101", "name": "JOAG1J", "description": "" }, { "id": "MONDO:0012101", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012101", "name": "JOAG2", "description": "" }, { "id": "MONDO:0012101", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012101", "name": "glaucoma 1, open angle, J", "description": "" }, { "id": "MONDO:0012102", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012102", "name": "glaucoma 1, open angle, K", "description": "" }, { "id": "MONDO:0012102", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012102", "name": "GLC1K", "description": "" }, { "id": "MONDO:0012102", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012102", "name": "JOAG1K", "description": "" }, { "id": "MONDO:0012102", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012102", "name": "glaucoma 1, open angle, K", "description": "" }, { "id": "MONDO:0012102", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012102", "name": "glaucoma 1K, primary open angle, juvenile-onset", "description": "" }, { "id": "MONDO:0012337", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012337", "name": "obsolete glaucoma 1, open angle, I", "description": "" }, { "id": "MONDO:0012337", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012337", "name": "GLC1I", "description": "" }, { "id": "MONDO:0012337", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012337", "name": "glaucoma 1, open angle, I", "description": "" }, { "id": "MONDO:0012357", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012357", "name": "obsolete glaucoma 1, open angle, G", "description": "OBSOLETE. Any open-angle glaucoma in which the cause of the disease is a mutation in the WDR36 gene." }, { "id": "MONDO:0012357", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012357", "name": "WDR36 open-angle glaucoma", "description": "" }, { "id": "MONDO:0012357", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012357", "name": "glaucoma 1, open angle, G", "description": "" }, { "id": "MONDO:0012357", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012357", "name": "glaucoma 1, open angle, type G", "description": "" }, { "id": "MONDO:0012357", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012357", "name": "open-angle glaucoma caused by mutation in WDR36", "description": "" }, { "id": "MONDO:0012357", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012357", "name": "GLC1G", "description": "" }, { "id": "MONDO:0012515", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012515", "name": "glaucoma 1, open angle, M", "description": "" }, { "id": "MONDO:0012515", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012515", "name": "GLC1M", "description": "" }, { "id": "MONDO:0012515", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012515", "name": "JOAG1M", "description": "" }, { "id": "MONDO:0012515", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012515", "name": "glaucoma 1, open angle, M", "description": "" }, { "id": "MONDO:0012645", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012645", "name": "glaucoma 1, open angle, N", "description": "" }, { "id": "MONDO:0012645", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012645", "name": "GLC1N", "description": "" }, { "id": "MONDO:0012645", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012645", "name": "JOAG1N", "description": "" }, { "id": "MONDO:0012645", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012645", "name": "glaucoma 1, open angle, N", "description": "" }, { "id": "MONDO:0012646", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012646", "name": "obsolete glaucoma 1, open angle, H", "description": "" }, { "id": "MONDO:0012646", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012646", "name": "GLC1H", "description": "" }, { "id": "MONDO:0012646", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012646", "name": "glaucoma 1, open angle, H", "description": "" }, { "id": "MONDO:0013134", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013134", "name": "glaucoma 1, open angle, O", "description": "Any open-angle glaucoma in which the cause of the disease is a mutation in the NTF4 gene." }, { "id": "MONDO:0013134", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013134", "name": "NTF4 open-angle glaucoma", "description": "" }, { "id": "MONDO:0013134", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013134", "name": "glaucoma 1, open angle, 1O", "description": "" }, { "id": "MONDO:0013134", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013134", "name": "glaucoma 1, open angle, O", "description": "" }, { "id": "MONDO:0013134", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013134", "name": "glaucoma 1, open angle, type O", "description": "" }, { "id": "MONDO:0013134", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013134", "name": "open-angle glaucoma caused by mutation in NTF4", "description": "" }, { "id": "MONDO:0013134", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013134", "name": "GLC1O", "description": "" }, { "id": "MIM:177700", "resource": "MIM", "url": "https://www.omim.org/entry/177700", "name": "Glaucoma 1, open angle, P", "description": "Glaucoma 1, open angle, P" }, { "id": "MIM:603383", "resource": "MIM", "url": "https://www.omim.org/entry/603383", "name": "Glaucoma 1, open angle, F", "description": "Glaucoma 1, open angle, F" }, { "id": "MIM:609887", "resource": "MIM", "url": "https://www.omim.org/entry/609887", "name": "Glaucoma 1, open angle, G", "description": "Glaucoma 1, open angle, G" }, { "id": "MIM:611276", "resource": "MIM", "url": "https://www.omim.org/entry/611276", "name": "Glaucoma 1, open angle, H", "description": "Glaucoma 1, open angle, H" }, { "id": "MIM:613100", "resource": "MIM", "url": "https://www.omim.org/entry/613100", "name": "Glaucoma 1, open angle, O", "description": "Glaucoma 1, open angle, O" } ], "unlinked_id_list": [], "evidence": [ { "id": "1067", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1067" } ] }, { "disease_id": "DOID:1074", "recommended_name": { "id": "DOID:1074", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1074", "name": "kidney failure", "description": "A kidney disease characterized by the failure of the kidneys to adequately filter waste products from the blood." }, "synonyms": [ { "id": "DOID:1074", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1074", "name": "renal failure", "description": "" }, { "id": "DOID:1074", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1074", "name": "Renal Insufficiency", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "1074", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1074" } ] }, { "disease_id": "DOID:10873", "recommended_name": { "id": "DOID:10873", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10873", "name": "Kuhnt-Junius degeneration", "description": "" }, "synonyms": [ { "id": "DOID:10873", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10873", "name": "Exudative senile macular degeneration of retina", "description": "" }, { "id": "DOID:10873", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10873", "name": "Neovascular age-related macular degeneration", "description": "" }, { "id": "DOID:10873", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10873", "name": "Senile macular degeneration, wet", "description": "" }, { "id": "DOID:10873", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10873", "name": "Wet senile macular retinal degeneration", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "10873", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10873" } ] }, { "disease_id": "DOID:10923", "recommended_name": { "id": "DOID:10923", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10923", "name": "sickle cell anemia", "description": "A sickle cell disease that is characterized by the replacement of both of the beta-globin subunits in hemoglobin with hemoglobin S, resulting in a low number of red blood cells, repeated infections, and periodic episodes of pain." }, "synonyms": [ { "id": "DOID:10923", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10923", "name": "Hb SC disease", "description": "" }, { "id": "DOID:10923", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10923", "name": "Hb-S/Hb-C disease", "description": "" }, { "id": "DOID:10923", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10923", "name": "Hb-SS disease without crisis", "description": "" }, { "id": "DOID:10923", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10923", "name": "Hemoglobin S disease without crisis", "description": "" }, { "id": "DOID:10923", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10923", "name": "Sickle-cell/Hb-C disease without crisis", "description": "" }, { "id": "DOID:10923", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10923", "name": "drepanocytosis", "description": "" }, { "id": "DOID:10923", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10923", "name": "haemoglobin SC disease", "description": "" }, { "id": "DOID:10923", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10923", "name": "hemoglobin SC disease", "description": "" }, { "id": "DOID:10923", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10923", "name": "sickle cell anaemia", "description": "" }, { "id": "DOID:10923", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10923", "name": "HbSS disease", "description": "" }, { "id": "DOID:10923", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10923", "name": "homozygous sickle cell disease", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "10923", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10923" } ] }, { "disease_id": "DOID:1094", "recommended_name": { "id": "DOID:1094", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1094", "name": "attention deficit hyperactivity disorder", "description": "A specific developmental disorder that is characterized by co-existence of attentional problems and hyperactivity, with each behavior occurring infrequently alone and symptoms starting before seven years of age." }, "synonyms": [ { "id": "DOID:1094", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1094", "name": "ADHD", "description": "" }, { "id": "DOID:1094", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1094", "name": "attention deficit disorder", "description": "" }, { "id": "DOID:1094", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1094", "name": "hyperkinetic disorder", "description": "" }, { "id": "MONDO:0012149", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012149", "name": "attention deficit-hyperactivity disorder, susceptibility to, 1", "description": "" }, { "id": "MONDO:0012149", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012149", "name": "ADHD1", "description": "" }, { "id": "MONDO:0012149", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012149", "name": "attention deficit-hyperactivity disorder, susceptibility to, 1", "description": "" }, { "id": "MONDO:0012149", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012149", "name": "attention deficit-hyperactivity disorder, susceptibility to, type 1", "description": "" }, { "id": "MONDO:0012150", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012150", "name": "attention deficit-hyperactivity disorder, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012150", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012150", "name": "ADHD2", "description": "" }, { "id": "MONDO:0012150", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012150", "name": "attention Deficit-hyperactivity disorder, susceptibility to, type 2", "description": "" }, { "id": "MONDO:0012150", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012150", "name": "attention deficit-hyperactivity disorder, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012151", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012151", "name": "attention deficit-hyperactivity disorder, susceptibility to, 3", "description": "" }, { "id": "MONDO:0012151", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012151", "name": "ADHD3", "description": "" }, { "id": "MONDO:0012151", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012151", "name": "attention Deficit-hyperactivity disorder, susceptibility to, type 3", "description": "" }, { "id": "MONDO:0012151", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012151", "name": "attention deficit-hyperactivity disorder, susceptibility to, 3", "description": "" }, { "id": "MONDO:0012152", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012152", "name": "attention deficit-hyperactivity disorder, susceptibility to, 4", "description": "" }, { "id": "MONDO:0012152", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012152", "name": "ADHD4", "description": "" }, { "id": "MONDO:0012152", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012152", "name": "attention 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instance of attention deficit-hyperactivity disorder that is caused by an inherited genomic modification in an individual." } ], "unlinked_id_list": [], "evidence": [ { "id": "1094", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1094" } ] }, { "disease_id": "DOID:11054", "recommended_name": { "id": "DOID:11054", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder." }, "synonyms": [ { "id": "DOID:11054", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11054", "name": "bladder cancer", "description": "" }, { "id": "DOID:11054", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11054", "name": "tumor of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder cancer", "description": "A primary or metastatic malignant neoplasm involving the bladder." }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "tumor of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "tumour of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "bladder cancer, somatic", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "cancer of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant bladder neoplasm", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant bladder tumor", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant bladder tumour", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of the urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of urinary 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"name": "malignant tumor of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor, urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumour of bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumour of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumour of the urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumour of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant urinary bladder neoplasm", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant urinary bladder tumor", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant urinary bladder tumour", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder cancer", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder malignant neoplasm", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder malignant tumor", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder malignant tumour", "description": "" }, { "id": "MIM:109800", "resource": "MIM", "url": "https://www.omim.org/entry/109800", "name": "Bladder cancer", "description": "Bladder cancer" } ], "unlinked_id_list": [], "evidence": [ { "id": "11054", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11054" } ] }, { "disease_id": "DOID:11512", "recommended_name": { "id": "DOID:11512", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11512", "name": "Budd-Chiari syndrome", "description": "A hepatic vascular disease that is characterized by a spectrum of disease states, including anatomic abnormalities and hypercoagulable disorders, resulting in hepatic venous outflow occlusion." }, "synonyms": [ { "id": "DOID:11512", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11512", "name": "hepatic 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"https://disease-ontology.org/term/DOID:11695", "name": "portal vein thrombosis", "description": "A hepatic vascular disease that is characterized by a blood clot that forms within the hepatic portal vein." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "11695", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11695" } ] }, { "disease_id": "DOID:12134", "recommended_name": { "id": "DOID:12134", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12134", "name": "factor VIII deficiency", "description": "A hemophilia that has_material_basis_in Factor VIII deficiency, which results in the formation of fibrin deficient clots which makes coagulation much more prolonged." }, "synonyms": [ { "id": "DOID:12134", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12134", "name": "Congenital factor VIII disorder", "description": "" }, { "id": "DOID:12134", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12134", "name": "Hemophilia A", "description": "" }, { "id": "DOID:12134", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12134", "name": "Subhemophilia", "description": "" }, { "id": "DOID:12134", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12134", "name": "classic hemophilia A", "description": "" }, { "id": "DOID:12134", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12134", "name": "classic hemophilia", "description": "" }, { "id": "MONDO:0010602", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010602", "name": "hemophilia A", "description": "The most common form of hemophilia characterized by spontaneous or prolonged hemorrhages due to factor VIII deficiency." }, { "id": "MONDO:0010602", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010602", "name": "congenital factor VIII disorder", "description": "" }, { "id": "MONDO:0010602", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010602", "name": "factor VIII deficiency", "description": "" }, { "id": "MONDO:0010602", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010602", "name": "haemophilia a, X-linked recessive", "description": "" }, { "id": "MONDO:0010602", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010602", "name": "haemophilia type A", "description": "" }, { "id": "MONDO:0010602", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010602", "name": "haemophilia type a", "description": "" }, { "id": "MONDO:0010602", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010602", "name": "hemophilia A", "description": "" }, { "id": "MONDO:0010602", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010602", "name": "hemophilia a, X-linked recessive", "description": "" 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"resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010602", "name": "autosomal haemophilia a", "description": "" }, { "id": "MONDO:0010602", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010602", "name": "classic haemophilia", "description": "" }, { "id": "MONDO:0010602", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010602", "name": "classic hemophilia", "description": "" }, { "id": "MONDO:0010602", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010602", "name": "classical haemophilia", "description": "" }, { "id": "MONDO:0010602", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010602", "name": "classical hemophilia", "description": "" }, { "id": "MONDO:0010602", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010602", "name": "factor 8 deficiency", "description": "" }, { "id": "MONDO:0010602", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010602", "name": "haemophilia A, congenital", "description": "" }, { "id": "MONDO:0010602", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010602", "name": "hem A", "description": "" }, { "id": "MONDO:0010602", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010602", "name": "hemophilia A, congenital", "description": "" }, { "id": "MIM:306700", "resource": "MIM", "url": "https://www.omim.org/entry/306700", "name": "Hemophilia A", "description": "Hemophilia A" } ], "unlinked_id_list": [], "evidence": [ { "id": "12134", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12134" } ] }, { "disease_id": "DOID:12336", "recommended_name": { "id": "DOID:12336", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12336", "name": "male infertility", "description": "" }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "12336", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12336" } ] }, { "disease_id": "DOID:12361", "recommended_name": { "id": "DOID:12361", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12361", "name": "Graves' disease", "description": "An autoimmune disease of endocrine system that involves production of excessive amount of thyroid hormones, located_in thyroid gland." }, "synonyms": [ { "id": "DOID:12361", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12361", "name": "Grave's disease", "description": "" }, { "id": "DOID:12361", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12361", "name": "Graves disease", "description": "" }, { "id": "DOID:12361", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12361", "name": "exophthalmic goiter", "description": "" }, { "id": "MONDO:0100489", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0100489", "name": "Graves disease, susceptibility to, 1", "description": "" }, { "id": "MONDO:0100489", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0100489", "name": "Graves disease, susceptibility to, 1", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "12361", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12361" } ] }, { "disease_id": "DOID:1287", "recommended_name": { "id": "DOID:1287", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1287", "name": "cardiovascular system disease", "description": "A disease of anatomical entity which occurs in the blood, heart, blood vessels or the lymphatic system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells or lymph to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis." }, "synonyms": [ { "id": "DOID:1287", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1287", "name": "disease of subdivision of hemolymphoid system", "description": "" } ], "unlinked_id_list": [ "DOID:176", "DOID:0050826", "DOID:11840", "DOID:3527", "DOID:3316", "DOID:10314", "DOID:12326", "DOID:5749", "DOID:0060091", "DOID:4193", "DOID:864", "DOID:5238", "DOID:60006", "DOID:175", "DOID:235", "DOID:471", "DOID:0050829", "DOID:9768", "DOID:2348", "DOID:13089", "DOID:0060051", "DOID:5805", "DOID:13731", "DOID:0050825", "DOID:60001", "DOID:866", "DOID:2462", "DOID:60007", "DOID:272", "DOID:9742", "DOID:1729", "DOID:0050828", "DOID:11130", "DOID:1271", "DOID:3850", "DOID:0060228" ], "evidence": [ { "id": "1287", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1287" } ] }, { "disease_id": "DOID:13001", "recommended_name": { "id": "DOID:13001", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13001", "name": "carotid stenosis", "description": "" }, "synonyms": [ { "id": "DOID:13001", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13001", "name": "Carotid artery stenosis", "description": "" }, { "id": "DOID:13001", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13001", "name": "Stenosis, carotid artery", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "13001", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13001" } ] }, { "disease_id": "DOID:13550", "recommended_name": { "id": "DOID:13550", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13550", "name": "angle-closure glaucoma", "description": "A glaucoma characterized by closure of the anterior chamber angle such that aqueous outflow is blocked and the intraocular pressure becomes inappropriately elevated leading to optic nerve damage and visual field loss. Angle-closure glaucoma has_symptom progressive peripheral vision loss, decreased vision, and pain, redness, and headache in acute cases. Angle closure glaucoma can be caused by anatomically narrow angle, injury to the trabecular meshwork, and injuries to the anterior chamber, such as neovascularization and uveitis." }, "synonyms": [ { "id": "DOID:13550", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13550", "name": "ACG - Angle-closure glaucoma", "description": "" }, { "id": "DOID:13550", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13550", "name": "Angle Closure Glaucoma", "description": "" }, { "id": "DOID:13550", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13550", "name": "Closed angle glaucoma", "description": "" }, { "id": "DOID:13550", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13550", "name": "Narrow cleft glaucoma", "description": "" }, { "id": "DOID:13550", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13550", "name": "primary open-angle glaucoma with narrow angles", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "13550", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13550" } ] }, { "disease_id": "DOID:14018", "recommended_name": { "id": "DOID:14018", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14018", "name": "alcoholic liver cirrhosis", "description": "" }, "synonyms": [ { "id": "DOID:14018", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14018", "name": "Alcoholic Cirrhosis", "description": "" }, { "id": "DOID:14018", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14018", "name": "Alcoholic cirrhosis of liver", "description": "" }, { "id": "DOID:14018", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14018", "name": "Laennec's cirrhosis", "description": "" }, { "id": "DOID:14018", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14018", "name": "Laennec's cirrhosis, alcoholic", "description": "" }, { "id": "DOID:14018", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14018", "name": "Portal cirrhosis", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "14018", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14018" } ] }, { "disease_id": "DOID:14250", "recommended_name": { "id": "DOID:14250", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14250", "name": "Down syndrome", "description": "A chromosomal duplication syndrome that is characterized by flat-looking facial features and weak muscle tone (hypotonia) in infancy and is caused by trisomy of all or a critical portion of chromosome 21 and is associated with intellectual disability." }, "synonyms": [ { "id": "DOID:14250", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14250", "name": "Complete trisomy 21 syndrome", "description": "" }, { "id": "DOID:14250", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14250", "name": "Down's syndrome", "description": "" }, { "id": "DOID:14250", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14250", "name": "Down's syndrome - trisomy 21", "description": "" }, { "id": "DOID:14250", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14250", "name": "Downs syndrome", "description": "" }, { "id": "DOID:14250", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14250", "name": "G Trisomy", "description": "" }, { "id": "DOID:14250", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14250", "name": "trisomy 21 syndrome", "description": "" }, { "id": "MONDO:0008608", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008608", "name": "Down syndrome", "description": "Down syndrome is a chromosomal abnormality caused by the presence of a third (partial or total) copy of the chromosome 21 genetic material and that is characterized by variable intellectual disability, muscular hypotonia, and joint laxity, often associated with a characteristic facial dysmorphism and various anomalies such as cardiac, gastrointestinal, or endocrine defects." }, { "id": "MONDO:0008608", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008608", "name": "Down syndrome", "description": "" }, { "id": "MONDO:0008608", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008608", "name": "Down syndrome, Isolated cases", "description": "" }, { "id": "MONDO:0008608", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008608", "name": "Down's syndrome", "description": "" }, { "id": "MONDO:0008608", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008608", "name": "leukemia, megakaryoblastic, with or without Down syndrome, somatic", "description": "" }, { "id": "MONDO:0008608", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008608", "name": "trisomy 21 (Down syndrome)", "description": "" }, { "id": "MONDO:0008608", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008608", "name": "complete trisomy 21 syndrome", "description": "" }, { "id": "MONDO:0008608", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008608", "name": "trisomy 21", "description": "" }, { "id": "MONDO:0008608", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008608", "name": "trisomy 21 syndrome", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "14250", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14250" } ] }, { "disease_id": "DOID:1459", "recommended_name": { "id": "DOID:1459", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1459", "name": "hypothyroidism", "description": "A thyroid gland disease which involves an underproduction of thyroid hormone." }, "synonyms": [ { "id": "DOID:1459", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1459", "name": "Thyroid deficiency", "description": "" }, { "id": "DOID:1459", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1459", "name": "Thyroid insufficiency", "description": "" } ], "unlinked_id_list": [ "DOID:0112183" ], "evidence": [ { "id": "1459", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1459" } ] }, { "disease_id": "DOID:1588", "recommended_name": { "id": "DOID:1588", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1588", "name": "thrombocytopenia", "description": "A blood platelet disease that is characterized by low a platelet count in the blood." }, "synonyms": [ { "id": "MONDO:0008555", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008555", "name": "thrombocytopenia 2", "description": "An autosomal dominant disorder caused by mutation(s) in the ANKRD26 gene, encoding ANKRD26 protein. Additionally, in one family, a mutation(s) has been identified in the MASTL gene, encoding serine/threonine-protein kinase greatwall. The condition is characterized by mild to moderate bruisability." }, { "id": "MONDO:0008555", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008555", "name": "thrombocytopenia 2", "description": "" }, { "id": "MONDO:0008555", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008555", "name": "thrombocytopenia type 2", "description": "" }, { "id": "MONDO:0008555", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008555", "name": "THC2", "description": "" }, { "id": "MONDO:0008555", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008555", "name": "thrombocytopenia autosomal dominant 2", "description": "" }, { "id": "MONDO:0010120", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010120", "name": "thrombocytopenia 3", "description": "" }, { "id": "MONDO:0010120", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010120", "name": "THC3", "description": "" }, { "id": "MONDO:0010120", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010120", "name": "thrombocytopenia 3", "description": "" }, { "id": "MONDO:0010308", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010308", "name": "thrombocytopenia, X-linked, with or without dyserythropoietic anemia", "description": "An X-linked condition caused by mutation(s) in the GATA1 gene, encoding erythroid transcription factor. It is characterized by thrombocytopenia, as well as abnormal platelet function and morphology. Dyserythropoietic anemia of variable severity may also be present." }, { "id": "MONDO:0010308", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010308", "name": "X-linked thrombocytopenia, with or without dyserythropoietic Anaemia", "description": "" }, { "id": "MONDO:0010308", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010308", "name": "X-linked thrombocytopenia, with or without dyserythropoietic Anemia", "description": "" }, { "id": "MONDO:0010308", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010308", "name": "thrombocytopenia, X-linked, with or without dyserythropoietic anemia", "description": "" }, { "id": "MONDO:0010308", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010308", "name": "thrombocytopenia, X-linked, with or without dyserythropoietic anemia, X-linked recessive", "description": "" }, { "id": "MONDO:0010308", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010308", "name": "XLTDA", "description": "" }, { "id": "MONDO:0010743", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010743", "name": "thrombocytopenia 1", "description": "" }, { "id": "MONDO:0010743", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010743", "name": "X-linked thrombocytopenia with normal platelets", "description": "" }, { "id": "MONDO:0010743", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010743", "name": "thrombocytopenia 1", "description": "" }, { "id": "MONDO:0010743", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010743", "name": "thrombocytopenia type 1", "description": "" }, { "id": "MONDO:0010743", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010743", "name": "thrombocytopenia, X-linked, X-linked recessive", "description": "" }, { "id": "MONDO:0010743", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010743", "name": "thrombocytopenia, X-linked, intermittent, X-linked recessive", "description": "" }, { "id": "MONDO:0010743", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010743", "name": "THC", "description": "" }, { "id": "MONDO:0010743", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010743", "name": "THC1", "description": "" }, { "id": "MONDO:0010743", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010743", "name": "X-linked thrombocytopenia", "description": "" }, { "id": "MONDO:0010743", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010743", "name": "XLT", "description": "" }, { "id": "MONDO:0012775", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012775", "name": "thrombocytopenia 4", "description": "Any thrombocytopenia in which the cause of the disease is a mutation in the CYCS gene." }, { "id": "MONDO:0012775", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012775", "name": "CYCS thrombocytopenia", "description": "" }, { "id": "MONDO:0012775", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012775", "name": "thrombocytopenia 4", "description": "" }, { "id": "MONDO:0012775", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012775", "name": "thrombocytopenia caused by mutation in CYCS", "description": "" }, { "id": "MONDO:0012775", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012775", "name": "thrombocytopenia type 4", "description": "" }, { "id": "MONDO:0012775", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012775", "name": "THC4", "description": "" }, { "id": "MIM:188000", "resource": "MIM", "url": "https://www.omim.org/entry/188000", "name": "Thrombocytopenia 2", "description": "Thrombocytopenia 2" }, { "id": "MIM:273900", "resource": "MIM", "url": "https://www.omim.org/entry/273900", "name": "Thrombocytopenia 3", "description": "Thrombocytopenia 3" }, { "id": "MIM:300367", "resource": "MIM", "url": "https://www.omim.org/entry/300367", "name": "X-linked dyserythropoietic anemia and thrombocytopenia", "description": "X-linked dyserythropoietic anemia and thrombocytopenia" }, { "id": "MIM:313900", "resource": "MIM", "url": "https://www.omim.org/entry/313900", "name": "Thrombocytopenia 1", "description": "Thrombocytopenia 1" }, { "id": "MIM:612004", "resource": "MIM", "url": "https://www.omim.org/entry/612004", "name": "Thrombocytopenia 4", "description": "Thrombocytopenia 4" } ], "unlinked_id_list": [], "evidence": [ { "id": "1588", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1588" } ] }, { "disease_id": "DOID:1727", "recommended_name": { "id": "DOID:1727", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1727", "name": "retinal vein occlusion", "description": "" }, "synonyms": [ { "id": "DOID:1727", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1727", "name": "Occlusion, of retinal vein", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "1727", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1727" } ] }, { "disease_id": "DOID:1749", "recommended_name": { "id": "DOID:1749", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1749", "name": "squamous cell carcinoma", "description": "A carcinoma that derives_from squamous epithelial cells." }, "synonyms": [ { "id": "DOID:1749", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1749", "name": "epidermoid carcinoma", "description": "" }, { "id": "DOID:1749", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1749", "name": "malignant squamous cell tumor", "description": "" }, { "id": "DOID:1749", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1749", "name": "squamous carcinoma", "description": "" }, { "id": "DOID:1749", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1749", "name": "squamous cell Epithelioma", "description": "" }, { "id": "DOID:1749", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1749", "name": "squamous cell cancer", "description": "" }, { "id": "DOID:1749", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1749", "name": "SCC", "description": "" } ], "unlinked_id_list": [ "DOID:3149" ], "evidence": [ { "id": "1749", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1749" } ] }, { "disease_id": "DOID:1793", "recommended_name": { "id": "DOID:1793", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas." }, "synonyms": [ { "id": "DOID:1793", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1793", "name": "Ca body of pancreas", "description": "" }, { "id": "DOID:1793", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1793", "name": "Ca head of pancreas", "description": "" }, { "id": "DOID:1793", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1793", "name": "Ca tail of pancreas", "description": "" }, { "id": "DOID:1793", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1793", "name": "malignant neoplasm of body of pancreas", "description": "" }, { "id": "DOID:1793", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1793", "name": "malignant neoplasm of head of pancreas", "description": "" }, { "id": "DOID:1793", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1793", "name": "malignant neoplasm of tail of pancreas", "description": "" }, { "id": "DOID:1793", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1793", "name": "pancreas neoplasm", "description": "" }, { "id": "DOID:1793", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1793", "name": "pancreatic neoplasm", "description": "" }, { "id": "DOID:1793", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1793", "name": "pancreatic tumor", "description": "" } ], "unlinked_id_list": [ "DOID:1795" ], "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ] }, { "disease_id": "DOID:1936", "recommended_name": { "id": "DOID:1936", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1936", "name": "atherosclerosis", "description": "An arteriosclerotic cardiovascular disease that is characterized by the build-up of fatty material and calcium deposition in the arterial wall resulting in partial or complete occlusion of the arterial lumen. Disease is located within the tunica intima of large and small arteries." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "1936", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1936" } ] }, { "disease_id": "DOID:1984", "recommended_name": { "id": "DOID:1984", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1984", "name": "rectal benign neoplasm", "description": "An intestinal benign neoplasm located_in the rectum." }, "synonyms": [ { "id": "DOID:1984", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1984", "name": "Rectal tumor", "description": "" }, { "id": "DOID:1984", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1984", "name": "neoplasm of rectum", "description": "" }, { "id": "DOID:1984", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1984", "name": "rectum neoplasm", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "1984", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1984" } ] }, { "disease_id": "DOID:2043", "recommended_name": { "id": "DOID:2043", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2043", "name": "hepatitis B", "description": "A viral hepatitis that results_in inflammation located_in liver, has_material_basis_in Hepatitis B virus (Orthohepadnavirus hominoidei), which is transmitted_by sexual contact, blood transfusions, or fomites like needles or syringes. The infection has_symptom fever, fatigue, loss of appetite, nausea, vomiting, abdominal pain, clay-colored bowel movements, joint pain, and jaundice." }, "synonyms": [ { "id": "DOID:2043", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2043", "name": "chronic hepatitis B", "description": "" }, { "id": "DOID:2043", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2043", "name": "hepatitis B infection", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "2043", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2043" } ] }, { "disease_id": "DOID:2154", "recommended_name": { "id": "DOID:2154", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2154", "name": "nephroblastoma", "description": "A kidney cancer that affects the kidneys and typically occuring in children." }, "synonyms": [ { "id": "DOID:2154", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2154", "name": "adult nephroblastoma", "description": "" }, { "id": "MONDO:0008679", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008679", "name": "Wilms tumor 1", "description": "An autosomal disorder due to pathogenic variants in the WT1 gene leading to an increased risk Wilms tumor and genitourinary abnormalities incorporating Denys-Drash syndrome and Frasier syndrome." }, { "id": "MONDO:0008679", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008679", "name": "Wilms' tumor", "description": "" }, { "id": "MONDO:0008679", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008679", "name": "Wilms' tumour", "description": "" }, { "id": "MONDO:0008679", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008679", "name": "renal Wilms tumor", "description": "" }, { "id": "MONDO:0008679", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008679", "name": "renal Wilms tumour", "description": "" }, { "id": "MONDO:0008679", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008679", "name": "WT1-related Wilms tumor predisposition", "description": "" }, { "id": "MONDO:0008679", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008679", "name": "Wilms tumor 1", "description": "" }, { "id": "MONDO:0008679", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008679", "name": "Wilms tumor type 1", "description": "" }, { "id": "MONDO:0008679", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008679", "name": "Wilms tumor, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008679", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008679", "name": "Wilms tumor, somatic", "description": "" }, { "id": "MONDO:0008679", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008679", "name": "Wilms tumor, type 1, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008679", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008679", "name": "Wilms tumour type 1", "description": "" }, { "id": "MONDO:0008679", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008679", "name": "WT1", "description": "" }, { "id": "MIM:194070", "resource": "MIM", "url": "https://www.omim.org/entry/194070", "name": "Wilms tumor 1", "description": "Wilms tumor 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "2154", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2154" } ] }, { "disease_id": "DOID:2355", "recommended_name": { "id": "DOID:2355", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2355", "name": "anemia", "description": "A hematopoietic system disease that is characterized by a decrease in the normal number of red blood cells." }, "synonyms": [ { "id": "DOID:2355", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2355", "name": "anaemia", "description": "" } ], "unlinked_id_list": [ "DOID:1342", "DOID:720", "DOID:11244" ], "evidence": [ { "id": "2355", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2355" } ] }, { "disease_id": "DOID:2388", "recommended_name": { "id": "DOID:2388", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2388", "name": "renal artery disease", "description": "" }, "synonyms": [ { "id": "DOID:2388", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2388", "name": "renal vascular disease", "description": "" }, { "id": "DOID:2388", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2388", "name": "vascular disorder of kidney", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "2388", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2388" } ] }, { "disease_id": "DOID:2452", "recommended_name": { "id": "DOID:2452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2452", "name": "thrombophilia", "description": "A blood coagulation disease that is characterized by an increased tendency to form clots." }, "synonyms": [ { "id": "DOID:2452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2452", "name": "hypercoagulability state", "description": "" }, { "id": "MONDO:0008559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008559", "name": "thrombophilia due to thrombin defect", "description": "The formation of a blood clot (thrombus) in the lumen of a vein." }, { "id": "MONDO:0008559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008559", "name": "Venous thromboembolism", "description": "" }, { "id": "MONDO:0008559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008559", "name": "prothrombin thrombophilia", "description": "" }, { "id": "MONDO:0008559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008559", "name": "prothrombin-related thrombophilia", "description": "" }, { "id": "MONDO:0008559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008559", "name": "thrombophilia 1 due to thrombin defect", "description": "" }, { "id": "MONDO:0008559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008559", "name": "thrombophilia due to thrombin defect", "description": "" }, { "id": "MONDO:0008559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008559", "name": "venous thromboembolism, susceptibility to", "description": "" }, { "id": "MONDO:0008559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008559", "name": "venous thrombosis, protection against", "description": "" }, { "id": "MONDO:0008559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008559", "name": "THPH1", "description": "" }, { "id": "MONDO:0008559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008559", "name": "factor II-related thrombophilia", "description": "" }, { "id": "MONDO:0008559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008559", "name": "hyperprothrombinemia", "description": "" }, { "id": "MONDO:0008559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008559", "name": "prothrombin 20210G>A thrombophilia", "description": "" }, { "id": "MONDO:0008559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008559", "name": "prothrombin G20210A thrombophilia", "description": "" }, { "id": "MIM:188050", "resource": "MIM", "url": "https://www.omim.org/entry/188050", "name": "Thrombophilia due to thrombin defect", "description": "Thrombophilia due to thrombin defect" } ], "unlinked_id_list": [], "evidence": [ { "id": "2452", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2452" } ] }, { "disease_id": "DOID:2671", "recommended_name": { "id": "DOID:2671", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2671", "name": "transitional cell carcinoma", "description": "A carcinoma that derives_from transitional epithelial cells." }, "synonyms": [ { "id": "DOID:2671", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2671", "name": "transitional carcinoma", "description": "" }, { "id": "DOID:2671", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2671", "name": "transitional cell tumor", "description": "" }, { "id": "DOID:2671", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2671", "name": "urothelial cell carcinoma", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "2671", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2671" } ] }, { "disease_id": "DOID:2841", "recommended_name": { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing." }, "synonyms": [ { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "bronchial hyperreactivity", "description": "" }, { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "chronic obstructive asthma", "description": "" }, { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "chronic obstructive asthma with acute exacerbation", "description": "" }, { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "chronic obstructive asthma with status asthmaticus", "description": "" }, { "id": "MONDO:0010940", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010940", "name": "inherited susceptibility to asthma", "description": "" }, { "id": "MONDO:0010940", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010940", "name": "asthma, nocturnal, susceptibility to", "description": "" }, { "id": "MIM:600807", "resource": "MIM", "url": "https://www.omim.org/entry/600807", "name": "Asthma", "description": "Asthma" } ], "unlinked_id_list": [ "DOID:0080811", "DOID:0080819" ], "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ] }, { "disease_id": "DOID:2921", "recommended_name": { "id": "DOID:2921", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2921", "name": "glomerulonephritis", "description": "A nephritis that causes inflammation of the glomeruli located_in kidney." }, "synonyms": [], "unlinked_id_list": [ "DOID:13138" ], "evidence": [ { "id": "2921", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2921" } ] }, { "disease_id": "DOID:2987", "recommended_name": { "id": "DOID:2987", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2987", "name": "familial Mediterranean fever", "description": "An autoinflammatory disease characterized by recurrent episodes of fever and acute inflammation of the membranes lining the abdomen, joints and lungs; that has_material_basis_in mutations in the MEFV gene, which encodes the protein pyrin." }, "synonyms": [ { "id": "DOID:2987", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2987", "name": "benign paroxysmal peritonitis", "description": "" }, { "id": "DOID:2987", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2987", "name": "FMF", "description": "" }, { "id": "MONDO:0007601", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007601", "name": "familial Mediterranean fever, autosomal dominant", "description": "" }, { "id": "MONDO:0007601", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007601", "name": "familial Mediterranean fever, AD", "description": "" }, { "id": "MONDO:0007601", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007601", "name": "familial Mediterranean fever, autosomal dominant", "description": "" }, { "id": "MONDO:0009572", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009572", "name": "autosomal recessive familial Mediterranean fever", "description": "Autosomal recessive form of familial Mediterranean fever." }, { "id": "MONDO:0009572", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009572", "name": "autosomal recessive familial Mediterranean fever", "description": "" }, { "id": "MONDO:0009572", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009572", "name": "familial Mediterranean fever, AR", "description": "" }, { "id": "MONDO:0009572", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009572", "name": "familial Mediterranean fever, autosomal recessive", "description": "" }, { "id": "MONDO:0009572", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009572", "name": "FMF", "description": "" }, { "id": "MONDO:0009572", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009572", "name": "familial Mediterranean fever", "description": "" }, { "id": "MIM:134610", "resource": "MIM", "url": "https://www.omim.org/entry/134610", "name": "Familial Mediterranean fever, autosomal dominant", "description": "Familial Mediterranean fever, autosomal dominant" }, { "id": "MIM:249100", "resource": "MIM", "url": "https://www.omim.org/entry/249100", "name": "Familial Mediterranean fever, autosomal recessive", "description": "Familial Mediterranean fever, autosomal recessive" } ], "unlinked_id_list": [], "evidence": [ { "id": "2987", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2987" } ] }, { "disease_id": "DOID:3146", "recommended_name": { "id": "DOID:3146", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3146", "name": "lipid metabolism disorder", "description": "An inherited metabolic disorder that involves the creation and degradation of lipids." }, "synonyms": [ { "id": "DOID:3146", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3146", "name": "dyslipidemia", "description": "" }, { "id": "DOID:3146", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3146", "name": "fatty acid metabolism disorder", "description": "" } ], "unlinked_id_list": [ "DOID:0111368", "DOID:0111417", "DOID:0050674" ], "evidence": [ { "id": "3146", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3146" } ] }, { "disease_id": "DOID:326", "recommended_name": { "id": "DOID:326", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:326", "name": "ischemia", "description": "A vascular disease that is characterized by a restriction in blood supply to tissues." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "326", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:326" } ] }, { "disease_id": "DOID:332", "recommended_name": { "id": "DOID:332", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:332", "name": "amyotrophic lateral sclerosis", "description": "A motor neuron disease that is characterized by muscle spasticity, rapidly progressive weakness due to muscle atrophy, difficulty in speaking, swallowing, and breathing." }, "synonyms": [ { "id": "DOID:332", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:332", "name": "ALS", "description": "" }, { "id": "DOID:332", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:332", "name": "Lou Gehrig's disease", "description": "" }, { "id": "DOID:332", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:332", "name": "motor neuron disease, bulbar", "description": "" }, { "id": "MONDO:0007103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007103", "name": "amyotrophic lateral sclerosis type 1", "description": "" }, { "id": "MONDO:0007103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007103", "name": "ALS1", "description": "" }, { "id": "MONDO:0007103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007103", "name": "amyotrophic lateral sclerosis 1", "description": "" }, { "id": "MONDO:0007103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007103", "name": "amyotrophic lateral sclerosis type 1", "description": "" }, { "id": "MONDO:0007103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007103", "name": "FALS", "description": "" }, { "id": "MONDO:0007103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007103", "name": "amyotrophic lateral sclerosis 1, autosomal dominant amyotrophic lateral sclerosis 1, autosomal recessive, included", "description": "" }, { "id": "MONDO:0007103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007103", "name": "amyotrophic lateral sclerosis 1, familial", "description": "" }, { "id": "MONDO:0007103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007103", "name": "amyotrophic lateral sclerosis, autosomal dominant", "description": "" }, { "id": "MONDO:0007103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007103", "name": "amyotrophic lateral sclerosis, familial", "description": "" }, { "id": "MONDO:0007103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007103", "name": "amyotrophic lateral sclerosis, sporadic", "description": "" }, { "id": "MONDO:0007103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007103", "name": "amyotrophic lateral sclerosis, sporadic, included", "description": "" }, { "id": "MIM:105400", "resource": "MIM", "url": "https://www.omim.org/entry/105400", "name": "Amyotrophic lateral sclerosis 1", "description": "Amyotrophic lateral sclerosis 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "332", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:332" } ] }, { "disease_id": "DOID:3347", "recommended_name": { "id": "DOID:3347", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3347", "name": "osteosarcoma", "description": "A bone sarcoma that is located_in bone that has_material_basis_in cells of mesenchymal origin. It usually involves bones and less frequently extraosseous sites. It often involves the long bones (particularly distal femur, proximal tibia, and proximal humerus)." }, "synonyms": [ { "id": "DOID:3347", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3347", "name": "Osteogenic sarcoma", "description": "" }, { "id": "DOID:3347", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3347", "name": "Skeletal sarcoma", "description": "" }, { "id": "DOID:3347", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3347", "name": "bone tissue neoplasm", "description": "" }, { "id": "DOID:3347", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3347", "name": "osteoid sarcoma", "description": "" }, { "id": "MONDO:0002629", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0002629", "name": "bone osteosarcoma", "description": "A usually aggressive malignant bone-forming mesenchymal neoplasm arising from the bone. It may arise de novo or from a pre-existing lesion of the bone. Pain and a palpable mass are the most frequent clinical sign and symptom. It may spread to other anatomic sites, particularly the lungs." }, { "id": "MONDO:0002629", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0002629", "name": "bone osteosarcoma", "description": "" }, { "id": "MONDO:0002629", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0002629", "name": "osteosarcoma of bone", "description": "" }, { "id": "MONDO:0002629", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0002629", "name": "osteosarcoma, somatic", "description": "" }, { "id": "MONDO:0002629", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0002629", "name": "osteosarcoma, somatic mutation", "description": "" }, { "id": "MIM:259500", "resource": "MIM", "url": "https://www.omim.org/entry/259500", "name": "Osteogenic sarcoma", "description": "Osteogenic sarcoma" } ], "unlinked_id_list": [], "evidence": [ { "id": "3347", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3347" } ] }, { "disease_id": "DOID:3393", "recommended_name": { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "coronary artery disease", "description": "An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles." }, "synonyms": [ { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "CHD", "description": "" }, { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "Coronary disease", "description": "" }, { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "coronary arteriosclerosis", "description": "" }, { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "coronary heart disease", "description": "" }, { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "Ischemic Heart Disease", "description": "" }, { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "myocardial ischemia", "description": "" }, { "id": "MONDO:0010331", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010331", "name": "coronary heart disease, susceptibility to, 3", "description": "" }, { "id": "MONDO:0010331", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010331", "name": "coronary heart disease, susceptibility to, 3", "description": "" }, { "id": "MONDO:0010331", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010331", "name": "coronary heart disease, susceptibility to, type 3", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary heart disease, susceptibility to, 1", "description": "Any coronary artery disease in which the cause of the disease is a mutation in the CX3CR1 gene." }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "CX3CR1 coronary artery disease", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary artery disease caused by mutation in CX3CR1", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary artery disease, resistance to", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary heart disease, susceptibility to", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary heart disease, susceptibility to, 1", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary heart disease, susceptibility to, type 1", "description": "" }, { "id": "MONDO:0012009", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012009", "name": "coronary heart disease, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012009", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012009", "name": "coronary heart disease, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012009", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012009", "name": "coronary heart disease, susceptibility to, type 2", "description": "" }, { "id": "MONDO:0012010", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012010", "name": "coronary heart disease, susceptibility to, 4", "description": "" }, { "id": "MONDO:0012010", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012010", "name": "coronary heart disease, susceptibility to, 4", "description": "" }, { "id": "MONDO:0012010", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012010", "name": "coronary heart disease, susceptibility to, type 4", "description": "" }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "coronary artery disease, autosomal dominant, 1", "description": "Any coronary artery disease in which the cause of the disease is a mutation in the MEF2A gene." }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "MEF2A coronary artery disease", "description": "" }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "coronary artery disease caused by mutation in MEF2A", "description": "" }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "coronary artery disease, autosomal dominant, 1", "description": "" }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "coronary artery disease, autosomal dominant, type 1", "description": "" }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "ADCAD1", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "coronary artery disease, autosomal dominant 2", "description": "Any coronary artery disease in which the cause of the disease is a mutation in the LRP6 gene." }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "LRP6 coronary artery disease", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "coronary artery disease caused by mutation in LRP6", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "coronary artery disease, autosomal dominant 2", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "coronary artery disease, autosomal dominant type 2", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "coronary artery disease, autosomal dominant, 2", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "ADCAD2", "description": "" }, { "id": "MONDO:0012628", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012628", "name": "coronary heart disease, susceptibility to, 8", "description": "" }, { "id": "MONDO:0012628", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012628", "name": "CHDS8", "description": "" }, { "id": "MONDO:0012628", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012628", "name": "coronary heart disease, susceptibility to, 8", "description": "" }, { "id": "MONDO:0012788", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012788", "name": "coronary heart disease, susceptibility to, 9", "description": "" }, { "id": "MONDO:0012788", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012788", "name": "CHDS9", "description": "" }, { "id": "MONDO:0012788", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012788", "name": "coronary heart disease, susceptibility to, 9", "description": "" }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "hydatidiform mole, recurrent, 2", "description": "Any complete hydatidiform mole in which the cause of the disease is a mutation in the KHDC3L gene." }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "KHDC3L complete hydatidiform mole", "description": "" }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "complete hydatidiform mole caused by mutation in KHDC3L", "description": "" }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "hydatidiform Mole, recurrent, type 2", "description": "" }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "hydatidiform mole, recurrent, 2", "description": "" }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "HYDM2", "description": "" }, { "id": "MIM:608320", "resource": "MIM", "url": "https://www.omim.org/entry/608320", "name": "Coronary artery disease, autosomal dominant, 1", "description": "Coronary artery disease, autosomal dominant, 1" }, { "id": "MIM:610947", "resource": "MIM", "url": "https://www.omim.org/entry/610947", "name": "Coronary artery disease, autosomal dominant, 2", "description": "Coronary artery disease, autosomal dominant, 2" }, { "id": "MIM:614293", "resource": "MIM", "url": "https://www.omim.org/entry/614293", "name": "Hydatidiform mole, recurrent, 2", "description": "Hydatidiform mole, recurrent, 2" } ], "unlinked_id_list": [ "DOID:11840" ], "evidence": [ { "id": "3393", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3393" } ] }, { "disease_id": "DOID:3526", "recommended_name": { "id": "DOID:3526", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3526", "name": "cerebral infarction", "description": "A cerebrovascular disease that is characterized by an area of necrotic tissue in the brain resulting from a blockage or narrowing in the arteries supplying blood and oxygen to the brain." }, "synonyms": [ { "id": "DOID:3526", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3526", "name": "Cerebral infarct", "description": "" }, { "id": "MONDO:0020671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0020671", "name": "obsolete susceptibility to ischemic stroke", "description": "" }, { "id": "MONDO:0020671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0020671", "name": "cerebral infarction, susceptibility to", "description": "" }, { "id": "MONDO:0020671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0020671", "name": "ischemic stroke, susceptibility to", "description": "" }, { "id": "MONDO:0020671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0020671", "name": "stroke, ischemic, susceptibility to", "description": "" }, { "id": "MONDO:0020671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0020671", "name": "stroke, susceptibility to", "description": "" }, { "id": "MIM:601367", "resource": "MIM", "url": "https://www.omim.org/entry/601367", "name": "Ischemic stroke", "description": "Ischemic stroke" } ], "unlinked_id_list": [], "evidence": [ { "id": "3526", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3526" } ] }, { "disease_id": "DOID:4362", "recommended_name": { "id": "DOID:4362", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4362", "name": "cervical cancer", "description": "A female reproductive organ cancer that is located_in the cervix." }, "synonyms": [ { "id": "DOID:4362", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4362", "name": "cervical neoplasm", "description": "" }, { "id": "DOID:4362", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4362", "name": "cervix cancer", "description": "" }, { "id": "DOID:4362", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4362", "name": "cervix uteri cancer", "description": "" }, { "id": "DOID:4362", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4362", "name": "neoplasm of uterine cervix", "description": "" }, { "id": "DOID:4362", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4362", "name": "tumor of the Cervix Uteri", "description": "" }, { "id": "DOID:4362", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4362", "name": "uterine cervical neoplasm", "description": "" }, { "id": "MONDO:0002974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0002974", "name": "cervical cancer", "description": "A primary or metastatic malignant neoplasm involving the cervix." }, { "id": "MONDO:0002974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0002974", "name": "cervical neoplasm", "description": "" }, { "id": "MONDO:0002974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0002974", "name": "tumor of the cervix uteri", "description": "" }, { "id": "MONDO:0002974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0002974", "name": "tumour of the cervix uteri", "description": "" }, { "id": "MONDO:0002974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0002974", "name": "uterine cervical neoplasm", "description": "" }, { "id": "MONDO:0002974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0002974", "name": "cancer of uterine cervix", "description": "" }, { "id": "MONDO:0002974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0002974", "name": "cervical cancer, somatic", "description": "" }, { "id": "MONDO:0002974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0002974", "name": "malignant cervical neoplasm", "description": "" }, { "id": "MONDO:0002974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0002974", "name": "malignant cervical tumor", "description": "" }, { "id": "MONDO:0002974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0002974", "name": "malignant cervical tumour", "description": "" }, { "id": "MONDO:0002974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0002974", "name": "malignant cervix neoplasm", "description": "" }, { "id": "MONDO:0002974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0002974", "name": "malignant cervix tumor", "description": "" }, { "id": "MONDO:0002974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0002974", "name": "malignant cervix tumour", "description": "" }, { "id": "MONDO:0002974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0002974", "name": "malignant cervix uteri neoplasm", "description": "" }, { "id": "MONDO:0002974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0002974", "name": "malignant cervix uteri tumor", "description": "" }, { "id": "MONDO:0002974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0002974", "name": "malignant cervix uteri tumour", "description": "" }, { "id": "MONDO:0002974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0002974", "name": "malignant neoplasm of cervix", "description": "" }, { "id": "MONDO:0002974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0002974", "name": "malignant neoplasm of cervix uteri", "description": "" }, { "id": "MONDO:0002974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0002974", "name": "malignant neoplasm of the cervix", "description": "" }, { "id": "MONDO:0002974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0002974", "name": "malignant neoplasm of the cervix uteri", "description": "" }, { "id": "MONDO:0002974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0002974", "name": "malignant neoplasm of the uterine cervix", "description": "" }, { "id": "MONDO:0002974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0002974", "name": "malignant neoplasm of uterine cervix", "description": "" }, { "id": "MONDO:0002974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0002974", "name": "malignant tumor of cervix", "description": "" }, { "id": "MONDO:0002974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0002974", "name": "malignant tumor of cervix uteri", "description": "" }, { "id": "MONDO:0002974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0002974", "name": "malignant tumor of the cervix", "description": "" }, { "id": "MONDO:0002974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0002974", "name": "malignant tumor of the cervix uteri", "description": "" }, { "id": "MONDO:0002974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0002974", "name": "malignant tumor of the uterine cervix", "description": "" }, { "id": "MONDO:0002974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0002974", "name": "malignant tumor of uterine cervix", "description": "" }, { "id": "MONDO:0002974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0002974", "name": "malignant tumour of cervix", "description": "" }, { "id": "MONDO:0002974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0002974", "name": "malignant tumour of cervix uteri", "description": "" }, { "id": "MONDO:0002974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0002974", "name": "malignant tumour of the cervix", "description": "" }, { "id": "MONDO:0002974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0002974", "name": "malignant tumour of the cervix uteri", "description": "" }, { "id": "MONDO:0002974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0002974", "name": "malignant tumour of the uterine cervix", "description": "" }, { "id": "MONDO:0002974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0002974", "name": "malignant tumour of uterine cervix", "description": "" }, { "id": "MONDO:0002974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0002974", "name": "malignant uterine cervix neoplasm", "description": "" }, { "id": "MONDO:0002974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0002974", "name": "malignant uterine cervix tumor", "description": "" }, { "id": "MONDO:0002974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0002974", "name": "malignant uterine cervix tumour", "description": "" }, { "id": "MONDO:0002974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0002974", "name": "uterine cervix cancer", "description": "" }, { "id": "MIM:603956", "resource": "MIM", "url": "https://www.omim.org/entry/603956", "name": "Cervical cancer", "description": "Cervical cancer" } ], "unlinked_id_list": [], "evidence": [ { "id": "4362", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4362" } ] }, { "disease_id": "DOID:4450", "recommended_name": { "id": "DOID:4450", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4450", "name": "renal cell carcinoma", "description": "A renal carcinoma that has_material_basis_in the lining of the proximal convoluted renal tubule of the kidney." }, "synonyms": [ { "id": "DOID:4450", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4450", "name": "RCC", "description": "" }, { "id": "DOID:4450", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4450", "name": "adenocarcinoma of kidney", "description": "" }, { "id": "DOID:4450", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4450", "name": "hypernephroma", "description": "" }, { "id": "MONDO:0010456", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010456", "name": "renal cell carcinoma, Xp11-associated", "description": "" }, { "id": "MONDO:0010456", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010456", "name": "renal cell carcinoma, Xp11-associated", "description": "" }, { "id": "MONDO:0010456", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010456", "name": "renal cell carcinoma, papillary, 1", "description": "" }, { "id": "MONDO:0010456", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010456", "name": "RCCX1", "description": "" }, { "id": "MIM:300854", "resource": "MIM", "url": "https://www.omim.org/entry/300854", "name": "Renal cell carcinoma Xp11-associated", "description": "Renal cell carcinoma Xp11-associated" } ], "unlinked_id_list": [ "DOID:4455" ], "evidence": [ { "id": "4450", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4450" } ] }, { "disease_id": "DOID:4467", "recommended_name": { "id": "DOID:4467", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4467", "name": "clear cell renal cell carcinoma", "description": "A renal cell carcinoma that has_material_basis_in cells that appear very pale or clear when examined under microscope." }, "synonyms": [ { "id": "DOID:4467", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4467", "name": "Clear cell carcinoma of kidney", "description": "" }, { "id": "DOID:4467", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4467", "name": "clear cell kidney carcinoma", "description": "" }, { "id": "DOID:4467", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4467", "name": "conventional (Clear cell) renal cell carcinoma", "description": "" }, { "id": "DOID:4467", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4467", "name": "conventional renal cell carcinoma", "description": "" }, { "id": "DOID:4467", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4467", "name": "renal clear cell carcinoma", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "4467", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4467" } ] }, { "disease_id": "DOID:4947", "recommended_name": { "id": "DOID:4947", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4947", "name": "cholangiocarcinoma", "description": "A bile duct adenocarcinoma that has_material_basis_in bile duct epithelial cells." }, "synonyms": [ { "id": "DOID:4947", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4947", "name": "adult primary Cholangiocarcinoma", "description": "" }, { "id": "DOID:4947", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4947", "name": "adult primary cholangiocellular carcinoma", "description": "" }, { "id": "DOID:4947", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4947", "name": "cholangiosarcoma", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "4947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4947" } ] }, { "disease_id": "DOID:5082", "recommended_name": { "id": "DOID:5082", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5082", "name": "liver cirrhosis", "description": "" }, "synonyms": [ { "id": "DOID:5082", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5082", "name": "Cirrhosis", "description": "" }, { "id": "DOID:5082", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5082", "name": "cirrhosis of liver", "description": "" }, { "id": "MONDO:0005155", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005155", "name": "cirrhosis of liver", "description": "A disorder characterized by replacement of the liver parenchyma with fibrous tissue and regenerative nodules. It is usually caused by alcoholism, hepatitis B, and hepatitis C. Complications include the development of ascites, esophageal varices, bleeding, and hepatic encephalopathy." }, { "id": "MONDO:0005155", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005155", "name": "cirrhosis", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "5082", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5082" } ] }, { "disease_id": "DOID:5409", "recommended_name": { "id": "DOID:5409", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5409", "name": "lung small cell carcinoma", "description": "A lung carcinoma that has_material_basis_in primitive-appearing cells that are smaller than normal cells and is located_in the lung." }, "synonyms": [ { "id": "MONDO:0008433", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008433", "name": "small cell lung carcinoma", "description": "Small cell lung cancer (SCLC) is a highly aggressive malignant neoplasm, accounting for 10-15% of lung cancer cases, characterized byrapid growth, and early metastasis. SCLC usually manifests as a large hilar mass with bulky mediastinal lymphadenopathy presenting clinically with chest pain, persistent cough, dyspnea, wheezing, hoarseness, hemoptysis, loss of appetite, weight loss, and neurological and endocrine paraneoplastic syndromes. SCLC is primarily reported in elderly people with a history of long-term tobacco exposure." }, { "id": "MONDO:0008433", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008433", "name": "SCLC", "description": "" }, { "id": "MONDO:0008433", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008433", "name": "oat cell carcinoma", "description": "" }, { "id": "MONDO:0008433", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008433", "name": "oat cell carcinoma (morphologic abnormality)", "description": "" }, { "id": "MONDO:0008433", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008433", "name": "poorly differentiated endocrine neoplasm", "description": "" }, { "id": "MONDO:0008433", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008433", "name": "Small cell lung cancer", "description": "" }, { "id": "MONDO:0008433", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008433", "name": "lung oat cell carcinoma", "description": "" }, { "id": "MONDO:0008433", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008433", "name": "lung small cell carcinoma", "description": "" }, { "id": "MONDO:0008433", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008433", "name": "lung small cell neuroendocrine carcinoma", "description": "" }, { "id": "MONDO:0008433", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008433", "name": "oat cell carcinoma of lung", "description": "" }, { "id": "MONDO:0008433", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008433", "name": "oat cell carcinoma of the lung", "description": "" }, { "id": "MONDO:0008433", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008433", "name": "oat cell lung carcinoma", "description": "" }, { "id": "MONDO:0008433", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008433", "name": "small cell cancer of the lung, somatic", "description": "" }, { "id": "MONDO:0008433", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008433", "name": "small cell carcinoma of lung", "description": "" }, { "id": "MONDO:0008433", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008433", "name": "small cell carcinoma of the lung", "description": "" }, { "id": "MONDO:0008433", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008433", "name": "small cell lung cancer", "description": "" }, { "id": "MONDO:0008433", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008433", "name": "small cell neuroendocrine carcinoma of lung", "description": "" }, { "id": "MONDO:0008433", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008433", "name": "small cell neuroendocrine carcinoma of the lung", "description": "" }, { "id": "MONDO:0008433", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008433", "name": "small-cell cancer of lung", "description": "" }, { "id": "MONDO:0008433", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008433", "name": "SCLC1", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "5409", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5409" } ] }, { "disease_id": "DOID:5419", "recommended_name": { "id": "DOID:5419", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness." }, "synonyms": [ { "id": "DOID:5419", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5419", "name": "schizophrenia-1", "description": "" }, { "id": "MONDO:0005090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005090", "name": "schizophrenia", "description": "A major psychotic disorder characterized by abnormalities in the perception or expression of reality. It affects the cognitive and psychomotor functions. Common clinical signs and symptoms include delusions, hallucinations, disorganized thinking, and retreat from reality." }, { "id": "MONDO:0005090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005090", "name": "schizophrenia 12", "description": "" }, { "id": "MONDO:0005090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005090", "name": "schizophrenia", "description": "" }, { "id": "MONDO:0005090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005090", "name": "schizophrenia (disease)", "description": "" }, { "id": "MONDO:0005090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005090", "name": "SCZD", "description": "" }, { "id": "MIM:181500", "resource": "MIM", "url": "https://www.omim.org/entry/181500", "name": "Schizophrenia", "description": "Schizophrenia" } ], "unlinked_id_list": [], "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ] }, { "disease_id": "DOID:5614", "recommended_name": { "id": "DOID:5614", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5614", "name": "eye disease", "description": "An eye and adnexa disease that is located_in the eye." }, "synonyms": [], "unlinked_id_list": [ "DOID:1242", "DOID:8500", "DOID:0060440", "DOID:12571", "DOID:240", "DOID:6970", "DOID:0111148", "DOID:0080637", "DOID:2007", "DOID:1400", "DOID:2174", "DOID:6929", "DOID:12318", "DOID:9720", "DOID:771", "DOID:0060443", "DOID:0060442", "DOID:5467", "DOID:3480", "DOID:1393", "DOID:2462", "DOID:1237", "DOID:0111797", "DOID:0060441", "DOID:4645", "DOID:9799", "DOID:9794", "DOID:3479", "DOID:0070438" ], "evidence": [ { "id": "5614", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5614" } ] }, { "disease_id": "DOID:5844", "recommended_name": { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia." }, "synonyms": [ { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "Myocardial infarct", "description": "" }, { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "heart attack", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, type 2", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ] }, { "disease_id": "DOID:61", "recommended_name": { "id": "DOID:61", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:61", "name": "mitral valve disease", "description": "" }, "synonyms": [ { "id": "DOID:61", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:61", "name": "Mitral RH valve dis.", "description": "" }, { "id": "DOID:61", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:61", "name": "Rheumatic mitral insufficiency", "description": "" }, { "id": "DOID:61", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:61", "name": "Rheumatic mitral valve changes", "description": "" }, { "id": "DOID:61", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:61", "name": "Rheumatic mitral valve regurgitation", "description": "" }, { "id": "DOID:61", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:61", "name": "chronic rheumatic mitral valve", "description": "" }, { "id": "DOID:61", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:61", "name": "disease of mitral valve", "description": "" }, { "id": "DOID:61", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:61", "name": "rheumatic disease of mitral valve", "description": "" }, { "id": "DOID:61", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:61", "name": "rheumatic mitral valve incompetence", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "61", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:61" } ] }, { "disease_id": "DOID:6364", "recommended_name": { "id": "DOID:6364", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:6364", "name": "migraine", "description": "A brain disease that is characterized by moderate to severe headaches, nausea, extreme sensitivity to light and sound and intense unilaterial throbbing or pulsing." }, "synonyms": [ { "id": "DOID:6364", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:6364", "name": "migraine disorder", "description": "" }, { "id": "DOID:6364", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:6364", "name": "migraine variant", "description": "" }, { "id": "DOID:6364", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:6364", "name": "migraine with or without aura", "description": "" }, { "id": "MONDO:0008000", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008000", "name": "migraine with or without aura, susceptibility to, 1", "description": "" }, { "id": "MONDO:0008000", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008000", "name": "migraine with or without aura, susceptibility to, 1", "description": "" }, { "id": "MONDO:0008000", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008000", "name": "migraine with or without aura, susceptibility to, type 1", "description": "" }, { "id": "MONDO:0008000", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008000", "name": "migraine without aura, susceptibility to", "description": "" }, { "id": "MONDO:0008000", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008000", "name": "migraine, resistance to", "description": "" }, { "id": "MONDO:0008000", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008000", "name": "migraine, susceptibility to", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "6364", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6364" } ] }, { "disease_id": "DOID:6419", "recommended_name": { "id": "DOID:6419", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:6419", "name": "tetralogy of Fallot", "description": "" }, "synonyms": [ { "id": "DOID:6419", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:6419", "name": "Ventricular septal defect with pulmonary stenosis or atresia, dextraposition of aorta, and hypertrophy of right ventricle", "description": "" }, { "id": "MONDO:0008542", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008542", "name": "tetralogy of fallot", "description": "Tetralogy of Fallot is a congenital cardiac malformation that consists of an interventricular communication, also known as a ventricular septal defect, obstruction of the right ventricular outflow tract, override of the ventricular septum by the aortic root, and right ventricular hypertrophy." }, { "id": "MONDO:0008542", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008542", "name": "tetralogy of fallot", "description": "" }, { "id": "MONDO:0008542", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008542", "name": "ventricular septal defect with pulmonary stenosis or atresia, dextraposition of aorta, and hypertrophy of right ventricle", "description": "" }, { "id": "MONDO:0008542", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008542", "name": "Fallot tetralogy", "description": "" }, { "id": "MONDO:0008542", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008542", "name": "TOF", "description": "" }, { "id": "MIM:187500", "resource": "MIM", "url": "https://www.omim.org/entry/187500", "name": "Tetralogy of Fallot", "description": "Tetralogy of Fallot" } ], "unlinked_id_list": [], "evidence": [ { "id": "6419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6419" } ] }, { "disease_id": "DOID:684", "recommended_name": { "id": "DOID:684", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver." }, "synonyms": [ { "id": "DOID:684", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:684", "name": "Hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma", "description": "A malignant tumor that arises from hepatocytes. Hepatocellular carcinoma is relatively rare in the United States but very common in all African countries south of the Sahara and in Southeast Asia. Most cases are seen in patients over the age of 50 years, but this tumor can also occur in younger individuals and even in children. Hepatocellular carcinoma is more common in males than females and is associated with hepatitis B, hepatitis C, chronic alcohol abuse and cirrhosis. Serum elevation of alpha-fetoprotein occurs in a large percentage of patients with hepatocellular carcinoma. Grossly, hepatocellular carcinoma may present as a single mass, as multiple nodules, or as diffuse liver involvement. Microscopically, there is a wide range of differentiation from tumor to tumor (well differentiated to poorly differentiated tumors). Hepatocellular carcinomas quickly metastasize to regional lymph nodes and lung. The overall median survival of untreated liver cell carcinoma is about 4 months. The most effective treatment of hepatocellular carcinoma is complete resection of the tumor. Lately, an increasing number of tumors have been treated with liver transplantation." }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "HCC", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "cancer, hepatocellular", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of liver", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of the liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma, hepatocellular, malignant", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatoblastoma, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular adenocarcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular cancer", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular cancer, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma, childhood type, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver cell cancer (hepatocellular carcinoma)", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver cell carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "primary carcinoma of liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "primary carcinoma of the liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "adult hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "adult primary hepatocellular carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma", "description": "A malignant tumor that arises from hepatocytes. Hepatocellular carcinoma is relatively rare in the United States but very common in all African countries south of the Sahara and in Southeast Asia. Most cases are seen in patients over the age of 50 years, but this tumor can also occur in younger individuals and even in children. Hepatocellular carcinoma is more common in males than females and is associated with hepatitis B, hepatitis C, chronic alcohol abuse and cirrhosis. Serum elevation of alpha-fetoprotein occurs in a large percentage of patients with hepatocellular carcinoma. Grossly, hepatocellular carcinoma may present as a single mass, as multiple nodules, or as diffuse liver involvement. Microscopically, there is a wide range of differentiation from tumor to tumor (well differentiated to poorly differentiated tumors). Hepatocellular carcinomas quickly metastasize to regional lymph nodes and lung. The overall median survival of untreated liver cell carcinoma is about 4 months. The most effective treatment of hepatocellular carcinoma is complete resection of the tumor. Lately, an increasing number of tumors have been treated with liver transplantation." }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "HCC", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "cancer, hepatocellular", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of liver", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of the liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma, hepatocellular, malignant", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatoblastoma, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular adenocarcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular cancer", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular cancer, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma, childhood type, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver cell cancer (hepatocellular carcinoma)", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver cell carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "primary carcinoma of liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "primary carcinoma of the liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "adult hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "adult primary hepatocellular carcinoma", "description": "" }, { "id": "MIM:114550", "resource": "MIM", "url": "https://www.omim.org/entry/114550", "name": "Hepatocellular carcinoma", "description": "Hepatocellular carcinoma" } ], "unlinked_id_list": [], "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ] }, { "disease_id": "DOID:7147", "recommended_name": { "id": "DOID:7147", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:7147", "name": "ankylosing spondylitis", "description": "An arthritis that results_in inflammation in the joints of the spine and pelvis. The disease has_symptom pain, has_symptom stiffness in the spine, has_symptom stiffness in the neck, has_symptom stiffness in the hips, has_symptom stiffness in the jaw and has_symptom stiffness in the rib cage." }, "synonyms": [ { "id": "DOID:7147", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:7147", "name": "Bekhterev syndrome", "description": "" }, { "id": "DOID:7147", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:7147", "name": "Bekhterev's disease", "description": "" }, { "id": "DOID:7147", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:7147", "name": "Marie-Strumpell disease", "description": "" }, { "id": "MONDO:0007126", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007126", "name": "spondyloarthropathy, susceptibility to, 1", "description": "Any spondyloarthropathy, susceptibility to in which the cause of the disease is a mutation in the HLA-B gene." }, { "id": "MONDO:0007126", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007126", "name": "HLA-B spondyloarthropathy, susceptibility to", "description": "" }, { "id": "MONDO:0007126", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007126", "name": "spondyloarthropathy, susceptibility to caused by mutation in HLA-B", "description": "" }, { "id": "MONDO:0007126", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007126", "name": "spondyloarthropathy, susceptibility to, 1", "description": "" }, { "id": "MONDO:0007126", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007126", "name": "spondyloarthropathy, susceptibility to, type 1", "description": "" }, { "id": "MONDO:0007126", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007126", "name": "SPDA1", "description": "" }, { "id": "MIM:106300", "resource": "MIM", "url": "https://www.omim.org/entry/106300", "name": "Spondyloarthropathy 1", "description": "Spondyloarthropathy 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "7147", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7147" } ] }, { "disease_id": "DOID:7148", "recommended_name": { "id": "DOID:7148", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:7148", "name": "rheumatoid arthritis", "description": "An arthritis that is an autoimmune disease which attacks healthy cells and tissue located_in joint." }, "synonyms": [ { "id": "DOID:7148", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:7148", "name": "Arthritis or polyarthritis, rheumatic", "description": "" }, { "id": "DOID:7148", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:7148", "name": "atrophic Arthritis", "description": "" }, { "id": "MONDO:0008383", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008383", "name": "rheumatoid arthritis", "description": "A chronic, systemic autoimmune disorder characterized by inflammation in the synovial membranes and articular surfaces. It manifests primarily as a symmetric, erosive polyarthritis that spares the axial skeleton and is typically associated with the presence in the serum of rheumatoid factor." }, { "id": "MONDO:0008383", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008383", "name": "RA", "description": "" }, { "id": "MONDO:0008383", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008383", "name": "rheumatoid arthritis", "description": "" }, { "id": "MIM:180300", "resource": "MIM", "url": "https://www.omim.org/entry/180300", "name": "Rheumatoid arthritis", "description": "Rheumatoid arthritis" } ], "unlinked_id_list": [], "evidence": [ { "id": "7148", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7148" } ] }, { "disease_id": "DOID:7693", "recommended_name": { "id": "DOID:7693", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:7693", "name": "abdominal aortic aneurysm", "description": "An aortic aneurysm that is located_in the abdominal aorta." }, "synonyms": [ { "id": "DOID:7693", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:7693", "name": "AORTIC ANEURYSM, FAMILIAL ABDOMINAL 1", "description": "" }, { "id": "MONDO:0012343", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012343", "name": "aortic aneurysm, familial abdominal, 2", "description": "" }, { "id": "MONDO:0012343", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012343", "name": "AAA2", "description": "" }, { "id": "MONDO:0012343", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012343", "name": "aortic aneurysm, familial abdominal 2", "description": "" }, { "id": "MONDO:0012343", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012343", "name": "aortic aneurysm, familial abdominal, 2", "description": "" }, { "id": "MONDO:0012751", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012751", "name": "aortic aneurysm, familial abdominal, 3", "description": "" }, { "id": "MONDO:0012751", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012751", "name": "AAA3", "description": "" }, { "id": "MONDO:0012751", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012751", "name": "aneurysm, familial abdominal 3", "description": "" }, { "id": "MONDO:0012751", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012751", "name": "aortic aneurysm, familial abdominal, 3", "description": "" }, { "id": "MONDO:0013716", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013716", "name": "aortic aneurysm, familial abdominal, 4", "description": "" }, { "id": "MONDO:0013716", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013716", "name": "AAA4", "description": "" }, { "id": "MONDO:0013716", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013716", "name": "aortic aneurysm, familial abdominal, 4", "description": "" }, { "id": "MONDO:0024521", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024521", "name": "aortic aneurysm, familial abdominal, 1", "description": "" }, { "id": "MONDO:0024521", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024521", "name": "AAA1", "description": "" }, { "id": "MONDO:0024521", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024521", "name": "aortic aneurysm, familial abdominal 1", "description": "" }, { "id": "MONDO:0024521", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024521", "name": "aortic aneurysm, familial abdominal, 1", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "7693", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7693" } ] }, { "disease_id": "DOID:783", "recommended_name": { "id": "DOID:783", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:783", "name": "end stage renal disease", "description": "A chronic kidney disease is characterized by non-functioning kidneys, as the final stage in chronic kidney disease." }, "synonyms": [ { "id": "DOID:783", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:783", "name": "end stage renal failure", "description": "" }, { "id": "DOID:783", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:783", "name": "end-stage kidney disease", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "783", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:783" } ] }, { "disease_id": "DOID:784", "recommended_name": { "id": "DOID:784", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:784", "name": "chronic kidney disease", "description": "A kidney failure that is characterized by the gradual loss of kidney function, present for a minimum of 3 months. CKD is classified based on cause, glomerular filtration rate (GFR) category (G2-G5), and albuminuria category (A1-A3)." }, "synonyms": [ { "id": "DOID:784", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:784", "name": "CKD", "description": "" }, { "id": "DOID:784", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:784", "name": "CRF", "description": "" }, { "id": "DOID:784", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:784", "name": "chronic kidney failure", "description": "" }, { "id": "DOID:784", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:784", "name": "chronic renal disease", "description": "" }, { "id": "DOID:784", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:784", "name": "chronic renal failure syndrome", "description": "" }, { "id": "DOID:784", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:784", "name": "renal failure - chronic", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "784", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:784" } ] }, { "disease_id": "DOID:7998", "recommended_name": { "id": "DOID:7998", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:7998", "name": "hyperthyroidism", "description": "A thyroid gland disease that involves an over production of thyroid hormone." }, "synonyms": [ { "id": "DOID:7998", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:7998", "name": "overactive thyroid", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "7998", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7998" } ] }, { "disease_id": "DOID:83", "recommended_name": { "id": "DOID:83", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:83", "name": "cataract", "description": "A lens disease characterized by clouding of the lens inside the eye which leads to a decrease in vision." }, "synonyms": [ { "id": "MONDO:0007285", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007285", "name": "cataract 1 multiple types", "description": "Any cataract (disease) in which the cause of the disease is a mutation in the GJA8 gene." }, { "id": "MONDO:0007285", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007285", "name": "CTRCT1", "description": "" }, { "id": "MONDO:0007285", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007285", "name": "GJA8 cataract (disease)", "description": "" }, { "id": "MONDO:0007285", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007285", "name": "cataract (disease) caused by mutation in GJA8", "description": "" }, { "id": "MONDO:0007285", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007285", "name": "cataract 1, multiple types, with or without microcornea", "description": "" }, { "id": "MONDO:0007285", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007285", "name": "cataract 1, multiple types", "description": "" }, { "id": "MONDO:0011060", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011060", "name": "early-onset non-syndromic cataract", "description": "Early-onset non-syndromic cataract is a rare, genetic, non-syndromic developmental defect of the eye, with high clinical and genetic heterogeneity, most frequently characterized by bilateral, symmetrical, non-progressive cataracts which present at birth or in early-childhood. Additional ocular manifestations (e.g. anterior segment dysgenesis, colobomas, nystagmus, microcornea, microphthalmia, myopia) may be associated, however other organs/systems are usually not affected." }, { "id": "MIM:116200", "resource": "MIM", "url": "https://www.omim.org/entry/116200", "name": "Cataract 1, multiple types", "description": "Cataract 1, multiple types" } ], "unlinked_id_list": [], "evidence": [ { "id": "83", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:83" } ] }, { "disease_id": "DOID:8552", "recommended_name": { "id": "DOID:8552", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8552", "name": "chronic myeloid leukemia", "description": "A myeloid leukemia that is characterized by over production of white blood cells." }, "synonyms": [ { "id": "DOID:8552", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8552", "name": "CML", "description": "" }, { "id": "DOID:8552", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8552", "name": "CML - chronic Myelogenous Leukemia", "description": "" }, { "id": "DOID:8552", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8552", "name": "Myeloid Leukemia, chronic", "description": "" }, { "id": "DOID:8552", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8552", "name": "chronic granulocytic leukaemia", "description": "" }, { "id": "DOID:8552", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8552", "name": "chronic granulocytic leukemia", "description": "" }, { "id": "DOID:8552", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8552", "name": "chronic myelogenous leukaemia", "description": "" }, { "id": "DOID:8552", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8552", "name": "chronic myelogenous leukemia", "description": "" }, { "id": "DOID:8552", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8552", "name": "chronic myeloid leukaemia", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "chronic myeloid leukemia", "description": "A chronic myeloproliferative neoplasm characterized by the expression of the BCR-ABL1 fusion gene. It presents with neutrophilic leukocytosis. It can appear at any age, but it mostly affects middle aged and older individuals. Patients usually present with fatigue, weight loss, anemia, night sweats, and splenomegaly. If untreated, it follows a biphasic or triphasic natural course; an initial indolent chronic phase which is followed by an accelerated phase, a blast phase, or both. Allogeneic stem cell transplantation and tyrosine kinase inhibitors delay disease progression and prolong overall survival." }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "BCR-ABL Positive chronic myelogenous leukaemia", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "BCR-ABL Positive chronic myelogenous leukemia", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "CML", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "CML - chronic myelogenous leukaemia", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "CML - chronic myelogenous leukemia", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "chronic granulocytic leukemia", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "chronic myelocytic leukaemia", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "chronic myelocytic leukemia", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "chronic myelogenous leukaemia (CML)", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "chronic myelogenous leukemia", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "chronic myelogenous leukemia (CML)", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "chronic myelogenous leukemia, BCR-ABL1 Positive", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "chronic myelogenous leukemias", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "chronic myeloid leukemia", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "hematopoeitic - chronic myelocytic leukaemia (CML)", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "hematopoeitic - chronic myelocytic leukemia (CML)", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "leukimia, chronic myeloid", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "myeloid leukemia, chronic", "description": "" }, { "id": "MIM:608232", "resource": "MIM", "url": "https://www.omim.org/entry/608232", "name": "Leukemia, chronic myeloid, atypical", "description": "Leukemia, chronic myeloid, atypical" } ], "unlinked_id_list": [], "evidence": [ { "id": "8552", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8552" } ] }, { "disease_id": "DOID:8736", "recommended_name": { "id": "DOID:8736", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8736", "name": "smallpox", "description": "A viral infectious disease that results in infection located in skin, has_material_basis_in Variola virus (Orthopoxvirus variola), which is transmitted by droplets from oral, nasal or pharyngeal mucosa, transmitted by contact with the body fluids, or transmitted by fomites. The infection results in formation of lesions, first on the face, hands and forearms and later on the trunk." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "8736", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8736" } ] }, { "disease_id": "DOID:8947", "recommended_name": { "id": "DOID:8947", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8947", "name": "diabetic retinopathy", "description": "" }, "synonyms": [ { "id": "DOID:8947", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8947", "name": "Retinal abnormality - diabetes-related", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "8947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8947" } ] }, { "disease_id": "DOID:9119", "recommended_name": { "id": "DOID:9119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9119", "name": "acute myeloid leukemia", "description": "A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells." }, "synonyms": [ { "id": "DOID:9119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9119", "name": "AML - acute Myeloid Leukemia", "description": "" }, { "id": "DOID:9119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9119", "name": "Leukemia, Myelocytic, acute", "description": "" }, { "id": "DOID:9119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9119", "name": "acute myeloblastic leukaemia", "description": "" }, { "id": "DOID:9119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9119", "name": "acute myeloblastic leukemia", "description": "" }, { "id": "DOID:9119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9119", "name": "acute myelogenous leukaemia", "description": "" }, { "id": "DOID:9119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9119", "name": "acute myelogenous leukemia", "description": "" }, { "id": "DOID:9119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9119", "name": "acute myeloid leukaemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myeloid leukemia", "description": "Acute myeloid leukemia (AML) is a group of neoplasms arising from precursor cells committed to the myeloid cell-line differentiation. All of them are characterized by clonal expansion of myeloid blasts. AML manifests by fever, pallor, anemia, hemorrhages and recurrent infections." }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "AML", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "AML - acute myeloid leukaemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "AML - acute myeloid leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "ANLL", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute Nonlymphocytic leukaemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute Nonlymphocytic leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute granulocytic leukaemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute granulocytic leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myeloblastic leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myelocytic leukaemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myelocytic leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myelogenous leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myelogenous leukemias", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myeloid leukaemia (AML)", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myeloid leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myeloid leukemia (AML)", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myeloid leukemia, somatic", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute nonlymphocytic leukaemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute nonlymphocytic leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "hematopoeitic - acute Myleogenous leukaemia (AML)", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "hematopoeitic - acute Myleogenous leukemia (AML)", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "leukemia, acute myeloid, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "leukemia, acute myeloid, reduced survival in, somatic", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "leukemia, acute myeloid, somatic", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "leukemia, acute myeloid, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "leukemia, myelocytic, acute", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "myeloid leukemia, acute", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "myeloid leukemia, acute, M4/M4Eo subtype, somatic", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute non lymphoblastic leukaemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute non lymphoblastic leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "leukemia, acute myeloid", "description": "" }, { "id": "MIM:601626", "resource": "MIM", "url": "https://www.omim.org/entry/601626", "name": "Leukemia, acute myelogenous", "description": "Leukemia, acute myelogenous" } ], "unlinked_id_list": [], "evidence": [ { "id": "9119", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9119" } ] }, { "disease_id": "DOID:916", "recommended_name": { "id": "DOID:916", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:916", "name": "liver benign neoplasm", "description": "" }, "synonyms": [ { "id": "DOID:916", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:916", "name": "epithelial hepatic and intrahepatic bile duct neoplasm", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "916", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:916" } ] }, { "disease_id": "DOID:9279", "recommended_name": { "id": "DOID:9279", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9279", "name": "hyperhomocysteinemia", "description": "An amino acid metabolic disorder that involves an abnormally large level of homocysteine in the blood." }, "synonyms": [ { "id": "MONDO:0004743", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0004743", "name": "hyperhomocysteinemia", "description": "A serious metabolic condition caused by mutations in the MTHFR gene, medications, or nutritional deficiency. It results in increased levels of homocysteine in the blood. Patients with this condition are at an increased risk for recurrent blood clots formation and cardiovascular accidents." }, { "id": "MONDO:0004743", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0004743", "name": "homocysteinemia", "description": "" }, { "id": "MONDO:0004743", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0004743", "name": "hyperhomocysteinemia", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "9279", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9279" } ] }, { "disease_id": "DOID:9296", "recommended_name": { "id": "DOID:9296", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9296", "name": "cleft lip", "description": "An orofacial cleft that is characterized by a congenital defect in the upper lip where the maxillary prominence fails to merge with the merged medial nasal prominences." }, "synonyms": [ { "id": "DOID:9296", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9296", "name": "Labium leporinum", "description": "" }, { "id": "DOID:9296", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9296", "name": "cheiloschisis", "description": "" }, { "id": "DOID:9296", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9296", "name": "cleft lip, unilateral, complete", "description": "" }, { "id": "DOID:9296", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9296", "name": "complete unilateral cleft lip", "description": "" }, { "id": "DOID:9296", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9296", "name": "hare lip", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "9296", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9296" } ] }, { "disease_id": "DOID:9352", "recommended_name": { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin." }, "synonyms": [ { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "NIDDM", "description": "" }, { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "non-insulin-dependent diabetes mellitus", "description": "" }, { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "type 2 diabetes", "description": "" }, { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "type II diabetes mellitus", "description": "" }, { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "insulin resistance", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type 2 diabetes mellitus", "description": "A type of diabetes mellitus that is characterized by insulin resistance or desensitization and increased blood glucose levels. This is a chronic disease that can develop gradually over the life of a patient and can be linked to both environmental factors and heredity." }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "NIDDM", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "T2D", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "T2DM", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "T2DM - type 2 diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "adult onset diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "adult-onset diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitis type 2", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitis type II", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent, association with", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent, late onset", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, type 2", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, type II", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes, type 2", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "insulin resistance, severe, digenic", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "non-insulin dependent diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "non-insulin dependent diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "noninsulin dependent diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "noninsulin-dependent diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type 2 diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type 2 diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type 2 diabetes mellitus non-insulin dependent", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type II diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type II diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent, 2", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "diabetes mellitus, noninsulin-dependent, 1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "diabetes mellitus, noninsulin-dependent 1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "diabetes mellitus, noninsulin-dependent, 1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "diabetes mellitus, noninsulin-dependent, type 1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "NIDDM1", "description": "" }, { "id": "MONDO:0011072", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011072", "name": "diabetes mellitus, noninsulin-dependent, 2", "description": "" }, { "id": "MONDO:0011072", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011072", "name": "NIDDM2", "description": "" }, { "id": "MONDO:0011072", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011072", "name": "diabetes mellitus, noninsulin-dependent, 2", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "diabetes mellitus, noninsulin-dependent, 3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "diabetes mellitus, noninsulin-dependent, 3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "diabetes mellitus, noninsulin-dependent, type 3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "type 2 diabetes mellitus 3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "NIDDM3", "description": "" }, { "id": "MONDO:0011955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011955", "name": "diabetes mellitus, noninsulin-dependent, 4", "description": "" }, { "id": "MONDO:0011955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011955", "name": "diabetes mellitus, noninsulin-dependent, 4", "description": "" }, { "id": "MONDO:0011955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011955", "name": "diabetes mellitus, noninsulin-dependent, type 4", "description": "" }, { "id": "MIM:125853", "resource": "MIM", "url": "https://www.omim.org/entry/125853", "name": "Type 2 diabetes mellitus", "description": "Type 2 diabetes mellitus" }, { "id": "MIM:601283", "resource": "MIM", "url": "https://www.omim.org/entry/601283", "name": "Type 2 diabetes mellitus 1", "description": "Type 2 diabetes mellitus 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ] }, { "disease_id": "DOID:9406", "recommended_name": { "id": "DOID:9406", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9406", "name": "hypopituitarism", "description": "A pituitary gland disease characterized by the decreased secretion of one or more of the eight hormones normally produced by the pituitary gland." }, "synonyms": [ { "id": "DOID:9406", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9406", "name": "Pituitary insufficiency", "description": "" }, { "id": "DOID:9406", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9406", "name": "pituitary hormone deficiency", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "9406", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9406" } ] }, { "disease_id": "DOID:9452", "recommended_name": { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "steatotic liver disease", "description": "A lipid storage disease characterized by the accumulation of large vacuoles of triglyceride fat in at least 5% of hepatocytes." }, "synonyms": [ { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "Fatty change of liver", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "Steatosis of liver", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "alcoholic fatty liver", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "hepatic lipidosis", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "SLD", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "fatty liver disease", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "hepatic steatosis", "description": "" }, { "id": "MONDO:0009220", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009220", "name": "visceral steatosis, congenital", "description": "" }, { "id": "MONDO:0009220", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009220", "name": "visceral steatosis, congenital", "description": "" }, { "id": "MONDO:0009220", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009220", "name": "fatal neonatal hepatic steatosis", "description": "" }, { "id": "MONDO:0009220", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009220", "name": "visceral steatosis", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "9452", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9452" } ] }, { "disease_id": "DOID:9538", "recommended_name": { "id": "DOID:9538", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9538", "name": "multiple myeloma", "description": "A myeloid neoplasm that is located_in the plasma cells in bone marrow." }, "synonyms": [ { "id": "DOID:9538", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9538", "name": "myeloma", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "plasma cell myeloma", "description": "A bone marrow-based plasma cell neoplasm characterized by a serum monoclonal protein and skeletal destruction with osteolytic lesions, pathological fractures, bone pain, hypercalcemia, and anemia. Clinical variants include non-secretory myeloma, smoldering myeloma, indolent myeloma, and plasma cell leukemia. (WHO, 2001)" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "Kahler disease", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "Kahler's disease", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "Multiple Myeloma", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "medullary plasmacytoma", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "multiple myeloma", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "multiple myeloma, resistance to, Somatic mutation", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "multiple myeloma, susceptibility to, Somatic mutation", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "multiple myeloma/plasma cell myeloma", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "myeloid neoplasm of plasma cell", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "myeloma", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "myeloma, multiple", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "myeloma, plasma cell, malignant", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "myelomatosis", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "plasma cell myeloid neoplasm", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "plasma cell myeloma", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "myeloma - multiple", "description": "" }, { "id": "MIM:254500", "resource": "MIM", "url": "https://www.omim.org/entry/254500", "name": "Multiple myeloma", "description": "Multiple myeloma" } ], "unlinked_id_list": [], "evidence": [ { "id": "9538", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9538" } ] }, { "disease_id": "DOID:9663", "recommended_name": { "id": "DOID:9663", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9663", "name": "aphthous stomatitis", "description": "A stomatitis characterized by the repeated formation of benign and non-contagious mouth ulcers." }, "synonyms": [ { "id": "DOID:9663", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9663", "name": "Aphtha", "description": "" }, { "id": "DOID:9663", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9663", "name": "Aphthous ulceration", "description": "" }, { "id": "DOID:9663", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9663", "name": "Canker sore", "description": "" }, { "id": "DOID:9663", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9663", "name": "Oral aphthae", "description": "" }, { "id": "DOID:9663", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9663", "name": "oral ulcer", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "9663", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9663" } ] }, { "disease_id": "DOID:9744", "recommended_name": { "id": "DOID:9744", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9744", "name": "type 1 diabetes mellitus", "description": "A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production." }, "synonyms": [ { "id": "DOID:9744", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9744", "name": "IDDM", "description": "" }, { "id": "DOID:9744", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9744", "name": "insulin-dependent diabetes mellitus", "description": "" }, { "id": "DOID:9744", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9744", "name": "type I diabetes mellitus", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "type 1 diabetes mellitus", "description": "A chronic condition characterized by minimal or absent production of insulin by the pancreas." }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "IDDM", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "T1D", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "T1DM", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "diabetes mellitis type 1", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "diabetes mellitis type I", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "immune mediated diabetes", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "insulin dependent diabetes", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "juvenile diabetes", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "type 1 diabetes", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "type I diabetes", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "type I diabetes mellitus", "description": "" }, { "id": "MIM:222100", "resource": "MIM", "url": "https://www.omim.org/entry/222100", "name": "Type 1 diabetes mellitus", "description": "Type 1 diabetes mellitus" } ], "unlinked_id_list": [], "evidence": [ { "id": "9744", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9744" } ] }, { "disease_id": "DOID:9849", "recommended_name": { "id": "DOID:9849", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9849", "name": "Meniere's disease", "description": "A vestibular disease characterized by vertigo, low-pitched tinnitus and hearing loss." }, "synonyms": [ { "id": "DOID:9849", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9849", "name": "Meniere disease", "description": "" }, { "id": "DOID:9849", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9849", "name": "Mnire's vertigo", "description": "" }, { "id": "DOID:9849", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9849", "name": "Otogenic vertigo", "description": "" }, { "id": "MONDO:0007972", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007972", "name": "Meniere disease", "description": "A disease of the inner ear (labyrinth) that is characterized by fluctuating sensorineural hearing loss; tinnitus; episodic vertigo; and aural fullness. It is the most common form of endolymphatic hydrops." }, { "id": "MONDO:0007972", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007972", "name": "Meniere disease", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "9849", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9849" } ] }, { "disease_id": "DOID:9952", "recommended_name": { "id": "DOID:9952", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9952", "name": "acute lymphoblastic leukemia", "description": "A acute leukemia that is characterized by over production of lymphoblasts." }, "synonyms": [ { "id": "DOID:9952", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9952", "name": "acute lymphoblastic leukaemia", "description": "" }, { "id": "DOID:9952", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9952", "name": "acute lymphocytic leukaemia", "description": "" }, { "id": "DOID:9952", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9952", "name": "ALL", "description": "" }, { "id": "DOID:9952", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9952", "name": "precursor lymphoblastic lymphoma/leukemia", "description": "" }, { "id": "MONDO:0009539", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009539", "name": "lymphoblastic leukemia, acute, with lymphomatous features", "description": "" }, { "id": "MONDO:0009539", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009539", "name": "leukemia, acute lymphoblastic", "description": "" }, { "id": "MONDO:0009539", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009539", "name": "lymphoblastic leukemia, acute, with lymphomatous features", "description": "" }, { "id": "MONDO:0009539", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009539", "name": "lall", "description": "" }, { "id": "MONDO:0013108", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013108", "name": "leukemia, acute lymphocytic, susceptibility to, 1", "description": "" }, { "id": "MONDO:0013108", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013108", "name": "T-cell acute lymphoblastic leukemia, somatic", "description": "" }, { "id": "MONDO:0013108", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013108", "name": "leukemia, T-cell acute lymphoblastic, somatic", "description": "" }, { "id": "MONDO:0013108", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013108", "name": "leukemia, T-cell acute lymphocytic, somatic", "description": "" }, { "id": "MONDO:0013108", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013108", "name": "leukemia, acute lymphoblastic, somatic", "description": "" }, { "id": "MONDO:0013108", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013108", "name": "leukemia, acute lymphocytic, Philadelphia chromosome positive, somatic", "description": "" }, { "id": "MONDO:0013108", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013108", "name": "leukemia, acute lymphocytic, susceptibility to, 1", "description": "" }, { "id": "MONDO:0013108", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013108", "name": "ALL", "description": "" }, { "id": "MONDO:0013108", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013108", "name": "leukemia, acute lymphoblastic", "description": "" }, { "id": "MIM:613065", "resource": "MIM", "url": "https://www.omim.org/entry/613065", "name": "Leukemia, acute lymphoblastic", "description": "Leukemia, acute lymphoblastic" } ], "unlinked_id_list": [ "DOID:0080638", "DOID:5604" ], "evidence": [ { "id": "9952", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9952" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VTI0", "url": "https://www.uniprot.org/uniprotkb/Q9VTI0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG7560", "url": "https://www.uniprot.org/uniprotkb/Q9VTI0", "locus": { "chromosome": "3L", "start_pos": 11426395, "end_pos": 11425158, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0036157", "url": "https://www.ensemblgenomes.org/id/FBgn0036157" } ] } } ], "crossref": [ { "id": "FB:FBgn0036157", "url": "https://alliancegenome.org/gene/FB:FBgn0036157", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0036157", "url": "https://bgee.org/?page=gene&gene_id=FBgn0036157", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00537", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00537", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0036157", "url": "https://flybase.org/reports/FBgn0036157", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "39276", "url": "https://www.ncbi.nlm.nih.gov/gene/39276", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003171", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003171", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029041", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029041", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG7560", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG7560", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WGFHFFT", "url": "https://omabrowser.org/oma/group/WGFHFFT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VTI0", "url": "https://www.orthodb.org/?gene=Q9VTI0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45754", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45754", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45754:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45754:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02219", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02219", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q9VTI0", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q9VTI0", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-DME-196757", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-196757", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_648462", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648462", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VTI0", "url": "https://www.uniprot.org/uniprotkb/Q9VTI0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VTI0-1", "url": "https://www.uniprot.org/uniprotkb/Q9VTI0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHAIQVPAGGSSPGAASYIPCVTFAPDQNESVVTKQRIGTLVAERTAQHRLFYGIEVMASDPSGRPTCLDFNHFLPLLPTFVSFVWLSQRYWDVEPVGQVESLQMAQHLATRIPVLPHVSAYRMSRQRLDQFLALNFSSLLAVRGDRVHEDQDFSISYPMVEQSIRQRGETISVCVGGYPEGYTSLGDIPQNSAKNMEFLKAKIDAGADCIITQLCYRPEVIVQFVKDCRAAGISVPIVVGLMSHESFRSYSMIEQITGVHLPDDLREQLDQLHSAHMKDMKSDQDLIRRFFVSLTVRTIRNVLDADVGVWGFHFFTLNRFKSVQAVLQELRDLDLLKDSEKDKKGYEK", "length": 349, "header": "tr|Q9VTI0-1|Q9VTI0_DROME Isoform 1 of Methylenetetrahydrofolate reductase-like catalytic domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG7560 PE=3 SV=2 CANONICAL=Q9VTI0-1" }, "isoforms": [ { "isoform_ac": "Q9VTI0-1", "url": "https://www.uniprot.org/uniprotkb/Q9VTI0/entry#Q9VTI0-1", "sequence": { "sequence": "MHAIQVPAGGSSPGAASYIPCVTFAPDQNESVVTKQRIGTLVAERTAQHRLFYGIEVMASDPSGRPTCLDFNHFLPLLPTFVSFVWLSQRYWDVEPVGQVESLQMAQHLATRIPVLPHVSAYRMSRQRLDQFLALNFSSLLAVRGDRVHEDQDFSISYPMVEQSIRQRGETISVCVGGYPEGYTSLGDIPQNSAKNMEFLKAKIDAGADCIITQLCYRPEVIVQFVKDCRAAGISVPIVVGLMSHESFRSYSMIEQITGVHLPDDLREQLDQLHSAHMKDMKSDQDLIRRFFVSLTVRTIRNVLDADVGVWGFHFFTLNRFKSVQAVLQELRDLDLLKDSEKDKKGYEK", "length": 349, "header": "tr|Q9VTI0-1|Q9VTI0_DROME Isoform 1 of Methylenetetrahydrofolate reductase-like catalytic domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG7560 PE=3 SV=2 CANONICAL=Q9VTI0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VTI0", "url": "https://www.uniprot.org/uniprotkb/Q9VTI0" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VTI0", "url": "https://www.uniprot.org/uniprotkb/Q9VTI0" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VTI0", "url": "https://www.uniprot.org/uniprotkb/Q9VTI0" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VTI0", "url": "https://www.uniprot.org/uniprotkb/Q9VTI0" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VTI0", "url": "https://www.uniprot.org/uniprotkb/Q9VTI0" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VTI0", "url": "https://www.uniprot.org/uniprotkb/Q9VTI0" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VTI0", "url": "https://www.uniprot.org/uniprotkb/Q9VTI0" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VTI0", "url": "https://www.uniprot.org/uniprotkb/Q9VTI0" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VTI0", "url": "https://www.uniprot.org/uniprotkb/Q9VTI0" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VTI0", "url": "https://www.uniprot.org/uniprotkb/Q9VTI0" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VTI0", "url": "https://www.uniprot.org/uniprotkb/Q9VTI0" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG7560", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG7560", "resource": "KEGG Pathway" }, { "id": "R-DME-196757", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-196757", "resource": "Reactome", "description": "Metabolism of folate and pterines" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A4C5-1", "protein_name": "Methylenetetrahydrofolate reductase", "gene_name": "Mthfr", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNHQKAGVLPDGHCYTSLGMWASEAGCVGLSVPPSIRNPAMSNEARRSGSPSPRSEGSSSGSESSKDSSRCSTPSLDPDRHERLREKMRRRMDSGDKWFSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTALNYCGLETILHMTCCQQRQEEISGHLHRAKQLGLKNIMALRGDPVGDHWEAEEGGFSYATDLVKHIRNEFGDYFDICVAGYPKGHPDAESFEDDLKHLKEKVSAGADFIITQLFFEASSFFSFVKACEDIGISCPILPGIFPIQGYTSLRQLVKLSKLEVPQTIKDVIEPIKDNDAAIRNYGIELAVNLCRELLDSGLVPGLHFYTLNREVATMEVLKQLGMWTEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQGWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESVFEVFEHYLSGEPNRHGYRVTCLPWNDEPLAAETSLMKEELLRVNRLGILTINSQPNINGKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIVQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVNLVDNEFLLDNCLWQVVEDTFELLNRHTTKKEAQAP", "length": 694 }, "evidence": [ { "id": "RGD:1309952", "url": "https://alliancegenome.org/gene/RGD:1309952#orthology", "database": "AGR" }, { "id": "MGI:106639", "url": "https://alliancegenome.org/gene/MGI:106639#orthology", "database": "AGR" }, { "id": "HGNC:7436", "url": "https://alliancegenome.org/gene/HGNC:7436#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041111-215", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041111-215#orthology", "database": "AGR" }, { "id": "FB:FBgn0036157", "url": "https://alliancegenome.org/gene/FB:FBgn0036157#orthology", "database": "AGR" }, { "id": "SGD:S000003093", "url": "https://alliancegenome.org/gene/SGD:S000003093#orthology", "database": "AGR" }, { "id": "SGD:S000005944", "url": "https://alliancegenome.org/gene/SGD:S000005944#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B0V153-1", "protein_name": "Methylenetetrahydrofolate reductase (NADPH)", "gene_name": "mthfr", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVNQRADVGWHSKSDSSGASNSGESSRESSRCSTPVPDADRTDRLRDKMKRRIESGDHWFSLEFFPPRTSSGAVNLISRFDRMGSGGPLFIDITWHPAGDPGSDKETSSMMIASTAVNYCGLESVLHLTCCNQTKEKITDHLNKAKRLGLKNIMALRGDPVGEDWVEEDGGFNFATDLVKHIRHEFDDYFDICVAGYPTGHPEAESYEDDLRHLKEKVDAGAHFIVTQLFFRAETFLKFVKDCRAIGITCPILPGIFPIQGYHSLRQLVKLSKLEVPEEIKQVIEPIKDNDAAIRNYGIQQAVEMCKVLLASGEVSGLHFYTLNREVATMEVLRQLGLWAEDPRRPLPWAISAHPKRKVEDVRPIFWASRPKSYIYRTQDWDDFPNGRWGNSSSPAFGELTDYYLFYLKSKSPKEALLQMWGEELMSEESVYEVFTNYITGQTNRSGHKVMCLPWNDDPLAPETNLLKDELEKVNRRGVLTINSQPNINGKASSDAIVGWGPAGGYVFQKAYLEFFTSSENVTALLQVLKKYEPRVNYQIVNVQGRNITNAHDMQPNAVTWGIFPGREIIQPTVVDPVSFMYWKDEAFALWIEQWAKLYEDESPSRMIIQYIHDNYFLVNLVDNDFPLDNCLWQVIEDMFALLDSSQVPQQEANEL", "length": 656 }, "evidence": [ { "id": "RGD:1309952", "url": "https://alliancegenome.org/gene/RGD:1309952#orthology", "database": "AGR" }, { "id": "MGI:106639", "url": "https://alliancegenome.org/gene/MGI:106639#orthology", "database": "AGR" }, { "id": "HGNC:7436", "url": "https://alliancegenome.org/gene/HGNC:7436#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041111-215", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041111-215#orthology", "database": "AGR" }, { "id": "FB:FBgn0036157", "url": "https://alliancegenome.org/gene/FB:FBgn0036157#orthology", "database": "AGR" }, { "id": "SGD:S000003093", "url": "https://alliancegenome.org/gene/SGD:S000003093#orthology", "database": "AGR" }, { "id": "SGD:S000005944", "url": "https://alliancegenome.org/gene/SGD:S000005944#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P42898-1", "protein_name": "Methylenetetrahydrofolate reductase (NADPH)", "gene_name": "MTHFR", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNEARGNSSLNPCLEGSASSGSESSKDSSRCSTPGLDPERHERLREKMRRRLESGDKWFSLEFFPPRTAEGAVNLISRFDRMAAGGPLYIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCRQRLEEITGHLHKAKQLGLKNIMALRGDPIGDQWEEEEGGFNYAVDLVKHIRSEFGDYFDICVAGYPKGHPEAGSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFVKACTDMGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCQELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDPRRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTSEESVFEVFVLYLSGEPNRNGHKVTCLPWNDEPLAAETSLLKEELLRVNRQGILTINSQPNINGKPSSDPIVGWGPSGGYVFQKAYLEFFTSRETAEALLQVLKKYELRVNYHLVNVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIERWGKLYEEESPSRTIIQYIHDNYFLVNLVDNDFPLDNCLWQVVEDTLELLNRPTQNARETEAP", "length": 656 }, "evidence": [ { "id": "RGD:1309952", "url": "https://alliancegenome.org/gene/RGD:1309952#orthology", "database": "AGR" }, { "id": "MGI:106639", "url": "https://alliancegenome.org/gene/MGI:106639#orthology", "database": "AGR" }, { "id": "HGNC:7436", "url": "https://alliancegenome.org/gene/HGNC:7436#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041111-215", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041111-215#orthology", "database": "AGR" }, { "id": "FB:FBgn0036157", "url": "https://alliancegenome.org/gene/FB:FBgn0036157#orthology", "database": "AGR" }, { "id": "SGD:S000003093", "url": "https://alliancegenome.org/gene/SGD:S000003093#orthology", "database": "AGR" }, { "id": "SGD:S000005944", "url": "https://alliancegenome.org/gene/SGD:S000005944#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P46151-1", "protein_name": "Methylenetetrahydrofolate reductase 1", "gene_name": "MET12", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSIRDLYHARASPFISLEFFPPKTELGTRNLMERMHRMTALDPLFITVTWGAGGTTAEKTLTLASLAQQTLNIPVCMHLTCTNTEKAIIDDALDRCYNAGIRNILALRGDPPIGEDWLDSQSNESPFKYAVDLVRYIKQSYGDKFCVGVAAYPEGHCEGEAEGHEQDPLKDLVYLKEKVEAGADFVITQLFYDVEKFLTFEMLFRERISQDLPLFPGLMPINSYLLFHRAAKLSHASIPPAILSRFPPEIQSDDNAVKSIGVDILIELIQEIYQRTSGRIKGFHFYTLNLEKAIAQIVSQSPVLSHIVNESSEEEGEDETSGEIGSIENVPIEDADGDIVLDDSNEETVANRKRRRHSSLDSAKLIFNRAIVTEKGLRYNNENGSMPSKKALISISKGHGTLGRDATWDEFPNGRFGDSRSPAYGEIDGYGPSIKVSKSKALELWGIPKTIGDLKDIFIKYLEGSTDAIPWSDLGLSAETALIQEELIQLNYRGYLTLASQPATNATLSSDKIFGWGPAKGRLYQKAFVEMFIHRQQWETTLKPKLDHYGRRKFSYYAGDSSGSFETNLDPHSSSVVTWGVFPNSPVKQTTIIEEESFKAWRDEAFSIWSEWAKLFPRNTPANILLRLVHKDYCLVSIVHHDFKETDELWEMLLDQA", "length": 657 }, "evidence": [ { "id": "RGD:1309952", "url": "https://alliancegenome.org/gene/RGD:1309952#orthology", "database": "AGR" }, { "id": "MGI:106639", "url": "https://alliancegenome.org/gene/MGI:106639#orthology", "database": "AGR" }, { "id": "HGNC:7436", "url": "https://alliancegenome.org/gene/HGNC:7436#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041111-215", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041111-215#orthology", "database": "AGR" }, { "id": "FB:FBgn0036157", "url": "https://alliancegenome.org/gene/FB:FBgn0036157#orthology", "database": "AGR" }, { "id": "SGD:S000005944", "url": "https://alliancegenome.org/gene/SGD:S000005944#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P53128-1", "protein_name": "Methylenetetrahydrofolate reductase 2", "gene_name": "MET13", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MKITEKLEQHRQTSGKPTYSFEYFVPKTTQGVQNLYDRMDRMYEASLPQFIDITWNAGGGRLSHLSTDLVATAQSVLGLETCMHLTCTNMPISMIDDALENAYHSGCQNILALRGDPPRDAENWTPVEGGFQYAKDLIKYIKSKYGDHFAIGVAGYPECHPELPNKDVKLDLEYLKQKIDAGGDFIITQMFYDVDNFINWCSQVRAAGMDVPIIPGIMPITTYAAFLRRAQWGQISIPQHFSSRLDPIKDDDELVRDIGTNLIVEMCQKLLDSGYVSHLHIYTMNLEKAPLMILERLNILPTESEFNAHPLAVLPWRKSLNPKRKNEEVRPIFWKRRPYSYVARTSQWAVDEFPNGRFGDSSSPAFGDLDLCGSDLIRQSANKCLELWSTPTSINDVAFLVINYLNGNLKCLPWSDIPINDEINPIKAHLIELNQHSIITINSQPQVNGIRSNDKIHGWGPKDGYVYQKQYLEFMLPKTKLPKLIDTLKNNEFLTYFAIDSQGDLLSNHPDNSKSNAVTWGIFPGREILQPTIVEKISFLAWKEEFYHILNEWKLNMNKYDKPHSAQFIQSLIDDYCLVNIVDNDYISPDDQIHSILLSL", "length": 600 }, "evidence": [ { "id": "RGD:1309952", "url": "https://alliancegenome.org/gene/RGD:1309952#orthology", "database": "AGR" }, { "id": "MGI:106639", "url": "https://alliancegenome.org/gene/MGI:106639#orthology", "database": "AGR" }, { "id": "HGNC:7436", "url": "https://alliancegenome.org/gene/HGNC:7436#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041111-215", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041111-215#orthology", "database": "AGR" }, { "id": "FB:FBgn0036157", "url": "https://alliancegenome.org/gene/FB:FBgn0036157#orthology", "database": "AGR" }, { "id": "SGD:S000003093", "url": "https://alliancegenome.org/gene/SGD:S000003093#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q9WU20-1", "protein_name": "Methylenetetrahydrofolate reductase (NADPH)", "gene_name": "Mthfr", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVNEARGSGSPNPRSEGSSSGSESSKDSSRCSTPSLDPERHERLREKMRRRMDSGDKWFSLEFFPPRTAEGAVNLISRFDRMAAGGPLFVDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCQQRPEEITGHLHRAKQLGLKNIMALRGDPVGDHWEAEEGGFSYATDLVKHIRTEFADYFDICVAGYPRGHPDAESFEDDLKHLKEKVSAGADFIITQLFFEASTFFSFVKACTEIGISCPILPGIFPIQGYTSLRQLVKLSKLEVPQKIKDVIEPIKDNDAAIRNYGIELAVSLCRELLDSGLVPGLHFYTLNREVATMEVLKQLGMWTEDPRRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMWGEELTSEESVFEVFEHYLSGEPNRHGYRVTCLPWNDEPLAAETSLMKEELLRVNRLGILTINSQPNINAKPSSDPVVGWGPSGGYVFQKAYLEFFTSRETVEALLQVLKTYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPISFMFWKDEAFALWIEQWGKLYEEESPSRMIIQYIHDNYFLVNLVDNEFPLDSCLWQVVEDTFELLNRHPTERETQAP", "length": 654 }, "evidence": [ { "id": "RGD:1309952", "url": "https://alliancegenome.org/gene/RGD:1309952#orthology", "database": "AGR" }, { "id": "MGI:106639", "url": "https://alliancegenome.org/gene/MGI:106639#orthology", "database": "AGR" }, { "id": "HGNC:7436", "url": "https://alliancegenome.org/gene/HGNC:7436#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041111-215", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041111-215#orthology", "database": "AGR" }, { "id": "FB:FBgn0036157", "url": "https://alliancegenome.org/gene/FB:FBgn0036157#orthology", "database": "AGR" }, { "id": "SGD:S000003093", "url": "https://alliancegenome.org/gene/SGD:S000003093#orthology", "database": "AGR" }, { "id": "SGD:S000005944", "url": "https://alliancegenome.org/gene/SGD:S000005944#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VTI0", "url": "https://www.uniprot.org/uniprotkb/Q9VTI0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "FAD binding", "id": "GO:0071949", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071949", "evidence": [ { "database": "UniProtKB", "id": "Q9VTI0", "url": "https://www.uniprot.org/uniprotkb/Q9VTI0" } ], "pmid": "" }, { "name": "methylenetetrahydrofolate reductase [NAD(P)H] activity", "id": "GO:0004489", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004489", "evidence": [ { "database": "UniProtKB", "id": "Q9VTI0", "url": "https://www.uniprot.org/uniprotkb/Q9VTI0" } ], "pmid": "" }, { "name": "methylenetetrahydrofolate reductase (NADPH) activity", "id": "GO:0106313", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106313", "evidence": [ { "database": "UniProtKB", "id": "Q9VTI0", "url": "https://www.uniprot.org/uniprotkb/Q9VTI0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "tetrahydrofolate interconversion", "id": "GO:0035999", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035999", "evidence": [ { "database": "UniProtKB", "id": "Q9VTI0", "url": "https://www.uniprot.org/uniprotkb/Q9VTI0" } ], "pmid": "" }, { "name": "methionine biosynthetic process", "id": "GO:0009086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009086", "evidence": [ { "database": "UniProtKB", "id": "Q9VTI0", "url": "https://www.uniprot.org/uniprotkb/Q9VTI0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 136, "end_pos": 138, "annotation": "n_glycosylation_sequon" }, { "start_pos": 29, "end_pos": 31, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VTI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTI0" }, { "id": "PF02219", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02219" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Methylenetetrahydrofolate reductase-like catalytic", "eco_id": "ECO_0000259", "start_pos": 105, "end_pos": 331, "start_aa": "Met", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 136, "end_pos": 138 }, { "start_pos": 29, "end_pos": 31 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VTK6-1", "uniprot_ac": "Q9VTK6", "uniprot_id": "Q9VTK6_DROME", "mass": { "chemical_mass": 58697.0, "monoisotopic_mass": 58697.0 }, "refseq": { "ac": "NP_001036599", "name": "uncharacterized protein, isoform B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001036599" }, "gene_names": [ { "name": "Dmel\\CG7368", "type": "recommended", "evidence": [ { "id": "Q9VTK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTK6" } ] }, { "name": "CG7368", "type": "synonym", "evidence": [ { "id": "NP_001036599", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001036599" }, { "id": "Q9VTK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTK6" } ] }, { "name": "Dmel\\CG7368", "type": "synonym", "evidence": [ { "id": "NP_001036599", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001036599" } ] }, { "name": "Dmel_CG7368", "type": "synonym", "evidence": [ { "id": "Q9VTK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTK6" } ] } ], "protein_names": [ { "name": "C2H2-type domain-containing protein", "type": "recommended", "evidence": [ { "id": "Q9VTK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTK6/entry#names_and_taxonomy" } ] }, { "name": "CG7368-PB", "type": "synonym", "evidence": [ { "id": "NP_001036599", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001036599" } ] }, { "name": "uncharacterized protein, isoform B", "type": "synonym", "evidence": [ { "id": "NP_001036599", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001036599" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VTK6", "url": "https://www.uniprot.org/uniprotkb/Q9VTK6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG7368", "url": "https://www.uniprot.org/uniprotkb/Q9VTK6", "locus": { "chromosome": "3L", "start_pos": 11605374, "end_pos": 11597202, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0036179", "url": "https://www.ensemblgenomes.org/id/FBgn0036179" } ] } } ], "crossref": [ { "id": "FB:FBgn0036179", "url": "https://alliancegenome.org/gene/FB:FBgn0036179", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0036179", "url": "https://bgee.org/?page=gene&gene_id=FBgn0036179", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0036179", "url": "https://flybase.org/reports/FBgn0036179", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "39301", "url": "https://www.ncbi.nlm.nih.gov/gene/39301", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VTK6", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VTK6*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG7368", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG7368", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FNQSHGP", "url": "https://omabrowser.org/oma/group/FNQSHGP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VTK6", "url": "https://www.orthodb.org/?gene=Q9VTK6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24394", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24394", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24394:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24394:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-3214815", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-3214815", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-9940951", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9940951", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001036599", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001036599", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VTK6", "url": "https://www.uniprot.org/uniprotkb/Q9VTK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VTK6-1", "url": "https://www.uniprot.org/uniprotkb/Q9VTK6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNFTPFGNTFPGNIPGLPQFTTSTAPLVSTVTAAVTDVTVTGTNNPQQQQQQDAAGSSNRYQQQQQQVTHFGQATMTAGQGSSGNKFRGGQDDAIQGDKYNGHLVASSQQQQQQQQQQQTQYATVAYASATATSAATDALQAGTSGQQQQQQQMQQQQVTAPQELTQDLCNAILQQQVLQNTSWQTLTPGTTVADYLSHLPANTLPLSLHHFLKYSAETIKKENQQNVVLQVQTGPAIGINTLGTTTISIPQQAEQLTLQPQQQATLQVQTQAAVTATATTATATTAGGSGATSGKKKKRKKRSKDRKTKLRPGEIRLGTALDGSPLYMCPECHVAYPEPELLEVHLVGHNLEKRYVCDICQASLKRKDHLTRHKQSHNPERPYICTVCLKAFKRKEQLSLHFVIHSGEKRHQCGECGKGFYRKDHLRKHTRSHIARRVKAELNSHVRRENGTSMLQPVVTEATTAALQHANQLASAQQQLQQQQQQQQQQQQQQQQQQQHHIVITQQQATPQQQQQTSQQQQQQQQMIN", "length": 530, "header": "tr|Q9VTK6-1|Q9VTK6_DROME Isoform 1 of C2H2-type domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG7368 PE=4 SV=1 CANONICAL=Q9VTK6-1" }, "isoforms": [ { "isoform_ac": "Q9VTK6-1", "url": "https://www.uniprot.org/uniprotkb/Q9VTK6/entry#Q9VTK6-1", "sequence": { "sequence": "MNFTPFGNTFPGNIPGLPQFTTSTAPLVSTVTAAVTDVTVTGTNNPQQQQQQDAAGSSNRYQQQQQQVTHFGQATMTAGQGSSGNKFRGGQDDAIQGDKYNGHLVASSQQQQQQQQQQQTQYATVAYASATATSAATDALQAGTSGQQQQQQQMQQQQVTAPQELTQDLCNAILQQQVLQNTSWQTLTPGTTVADYLSHLPANTLPLSLHHFLKYSAETIKKENQQNVVLQVQTGPAIGINTLGTTTISIPQQAEQLTLQPQQQATLQVQTQAAVTATATTATATTAGGSGATSGKKKKRKKRSKDRKTKLRPGEIRLGTALDGSPLYMCPECHVAYPEPELLEVHLVGHNLEKRYVCDICQASLKRKDHLTRHKQSHNPERPYICTVCLKAFKRKEQLSLHFVIHSGEKRHQCGECGKGFYRKDHLRKHTRSHIARRVKAELNSHVRRENGTSMLQPVVTEATTAALQHANQLASAQQQLQQQQQQQQQQQQQQQQQQQHHIVITQQQATPQQQQQTSQQQQQQQQMIN", "length": 530, "header": "tr|Q9VTK6-1|Q9VTK6_DROME Isoform 1 of C2H2-type domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG7368 PE=4 SV=1 CANONICAL=Q9VTK6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VTK6", "url": "https://www.uniprot.org/uniprotkb/Q9VTK6" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VTK6", "url": "https://www.uniprot.org/uniprotkb/Q9VTK6" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": 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"fragile x-associated primary ovarian insufficiency", "description": "" }, { "id": "MONDO:0010706", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010706", "name": "premature ovarian failure 1", "description": "" }, { "id": "MONDO:0010706", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010706", "name": "premature ovarian failure type 1", "description": "" }, { "id": "MONDO:0010706", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010706", "name": "primary ovarian failure caused by mutation in FMR1", "description": "" }, { "id": "MONDO:0010706", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010706", "name": "FMR1-related premature ovarian failure", "description": "" }, { "id": "MONDO:0010706", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010706", "name": "FMR1-related primary ovarian insufficiency", "description": "" }, { "id": "MONDO:0010706", 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"url": "https://www.ebi.ac.uk/interpro/entry/IPR036898", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045113", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045113", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG7339", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG7339", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LGPTLWW", "url": "https://omabrowser.org/oma/group/LGPTLWW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VTL6", "url": "https://www.orthodb.org/?gene=Q9VTL6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12709", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12709", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12709:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12709:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03876", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03876", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08292", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08292", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-76061", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-76061", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-76066", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-76066", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001261720", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261720", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VTL6", "url": "https://www.uniprot.org/uniprotkb/Q9VTL6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VTL6-1", "url": "https://www.uniprot.org/uniprotkb/Q9VTL6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFVLAELKDNVRIAPDQFHLKLVDAVRDEIDRKLANKVLLNVGLCIALKDIVSLKDSIILPGDGASHTEVLFRYVVFRPMVGTVITGKIRNCSREGVHVTLGFFDDILIPHAALQHPSRFDEAEQAWVWEYPLEDGAKHDLFMDVGEPIKFRVSREIFEETSPIGPPKTEAQTQQGASTSAAVASATSQEVKTPYRIIGAINESGLGVLSWWDQQGKDDEQDDEEDEEYDDEDGEGACEE", "length": 240, "header": "tr|Q9VTL6-1|Q9VTL6_DROME Isoform 1 of DNA-directed RNA polymerase III subunit RPC8 OS=Drosophila melanogaster OX=7227 GN=Polr3H PE=1 SV=1 CANONICAL=Q9VTL6-1" }, "isoforms": [ { "isoform_ac": "Q9VTL6-1", "url": "https://www.uniprot.org/uniprotkb/Q9VTL6/entry#Q9VTL6-1", "sequence": { "sequence": "MFVLAELKDNVRIAPDQFHLKLVDAVRDEIDRKLANKVLLNVGLCIALKDIVSLKDSIILPGDGASHTEVLFRYVVFRPMVGTVITGKIRNCSREGVHVTLGFFDDILIPHAALQHPSRFDEAEQAWVWEYPLEDGAKHDLFMDVGEPIKFRVSREIFEETSPIGPPKTEAQTQQGASTSAAVASATSQEVKTPYRIIGAINESGLGVLSWWDQQGKDDEQDDEEDEEYDDEDGEGACEE", "length": 240, "header": "tr|Q9VTL6-1|Q9VTL6_DROME Isoform 1 of DNA-directed RNA polymerase III subunit RPC8 OS=Drosophila melanogaster OX=7227 GN=Polr3H PE=1 SV=1 CANONICAL=Q9VTL6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VTL6", "url": "https://www.uniprot.org/uniprotkb/Q9VTL6" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VTL6", "url": "https://www.uniprot.org/uniprotkb/Q9VTL6" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VTL6", "url": "https://www.uniprot.org/uniprotkb/Q9VTL6" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VTL6", "url": "https://www.uniprot.org/uniprotkb/Q9VTL6" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VTL6", "url": "https://www.uniprot.org/uniprotkb/Q9VTL6" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VTL6", "url": "https://www.uniprot.org/uniprotkb/Q9VTL6" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VTL6", "url": "https://www.uniprot.org/uniprotkb/Q9VTL6" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VTL6", "url": "https://www.uniprot.org/uniprotkb/Q9VTL6" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VTL6", "url": "https://www.uniprot.org/uniprotkb/Q9VTL6" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VTL6", "url": "https://www.uniprot.org/uniprotkb/Q9VTL6" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VTL6", "url": "https://www.uniprot.org/uniprotkb/Q9VTL6" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG7339", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG7339", "resource": "KEGG Pathway" }, { "id": "R-DME-76061", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-76061", "resource": "Reactome", "description": "RNA Polymerase III Transcription Initiation From Type 1 Promoter" }, { "id": "R-DME-76066", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-76066", "resource": "Reactome", "description": "RNA Polymerase III Transcription Initiation From Type 2 Promoter" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1W1U5-1", "protein_name": "DNA-directed RNA polymerase subunit", "gene_name": "POLR3H", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFVLVEMVDTVRIPPWQFERKLNDSIAEELNKKLANKVVYNVGLCICLFDITKLEDAYVFPGDGASHTKVSLGFFDDILIPPESLQQPAKFDEAEQVWVWEYETEEGAHDLYMDTGEELRFRVVDESFVDTSPTGPSSAEAASSSEELPRKEAPYTLVGSICEPGLGLLSWWTSS", "length": 175 }, "evidence": [ { "id": "Q9VTL6", "url": "https://omabrowser.org/oma/group/Q9VTL6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0AAA9SMQ7-1", "protein_name": "DNA-directed RNA polymerase subunit", "gene_name": "POLR3H", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MFVLVEMVDTVRIPPWQFERKLNDSIAEELNKKLANKVVYNVGLCICLFDITKLEDAYVFPGDGASHTKVSLGFFDDILIPPESLQQPAKFDEAEQVWVWEYETEEGAHDLYMDIGEEVRFRVVDESFVDTSPTGPSSAEAASSSEELPKKEAPYTLMGSISEPGLGLLSWWTSS", "length": 175 }, "evidence": [ { "id": "Q9VTL6", "url": "https://omabrowser.org/oma/group/Q9VTL6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F7FCX9-1", "protein_name": "DNA-directed RNA polymerase subunit", "gene_name": "Polr3h", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFVLVEMVDTVRIPPWQFERKLNDSIAEELNKKLANKVVYNVGLCICLFDITKLEDAYVFPGDGASHTKVHFRYVVFHPFLDEILIGKIKGCSPEGVHVSLGFFDDILIPPESLQQPAKFDEAEQVWVWEYETEEGAHDLYMDTGEEIRFRVVDESFVDTSPTGPSSAEAASSSEELPKKEAPYTLVGSISEPGLGLLSWWTSN", "length": 204 }, "evidence": [ { "id": "FB:FBgn0036188", "url": "https://alliancegenome.org/gene/FB:FBgn0036188#orthology", "database": "AGR" }, { "id": "MGI:1926179", "url": "https://alliancegenome.org/gene/MGI:1926179#orthology", "database": "AGR" }, { "id": "HGNC:30349", "url": "https://alliancegenome.org/gene/HGNC:30349#orthology", "database": "AGR" }, { "id": "RGD:1305889", "url": "https://alliancegenome.org/gene/RGD:1305889#orthology", "database": "AGR" }, { "id": "SGD:S000001627", "url": "https://alliancegenome.org/gene/SGD:S000001627#orthology", "database": "AGR" }, { "id": "Q9VTL6", "url": "https://omabrowser.org/oma/group/Q9VTL6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P35718-1", "protein_name": "DNA-directed RNA 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"https://omabrowser.org/oma/group/Q9VTL6/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q557J3-1", "protein_name": "DNA-directed RNA polymerase III subunit rpc8", "gene_name": "polr3h-2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFHLITIEDKVRIAPSQFNNEVQTIEDEIEKKYTSKVVLNAGLFVALYDILGTGDSYVHSGDGGAHLMVRFRMVVFKPFKGEVLEGVIKKSSRQSIQISLGFFHEIYLNPIELPNPSNYNQEEGLWYWEWNENQLFFEDGGRVRFKIDQVEFNPEISQPAPSPKNVNTEAMDSYSLREYKEKQIENENLLKQVKSPLILKVSMREAGLGMVSWWTNQSAGDDDENEEDGGENQDDEVAEDDGGEEPTIEEDE", "length": 252 }, "evidence": [ { "id": "Q9VTL6", "url": "https://omabrowser.org/oma/group/Q9VTL6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9D2C6-1", "protein_name": "DNA-directed RNA polymerase III subunit RPC8", "gene_name": "Polr3h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFVLVEMVDTVRIPPWQFERKLNDSIAEELNKKLANKVVYNVGLCICLFDITKLEDAYVFPGDGASHTKVHFRYVVFHPFLDEILIGKIKGCSPEGVHVSLGFFDDILIPPESLQQPAKFDEAEQVWVWEYETEEGAHDLYMDTGEEIRFRVVDESFVDTSPTGPSSAEAASSSEELPKKEAPYTLVGSISEPGLGLLSWWTSN", "length": 204 }, "evidence": [ { "id": "FB:FBgn0036188", "url": "https://alliancegenome.org/gene/FB:FBgn0036188#orthology", "database": "AGR" }, { "id": "MGI:1926179", "url": "https://alliancegenome.org/gene/MGI:1926179#orthology", "database": "AGR" }, { "id": "HGNC:30349", "url": "https://alliancegenome.org/gene/HGNC:30349#orthology", "database": "AGR" }, { "id": "RGD:1305889", "url": "https://alliancegenome.org/gene/RGD:1305889#orthology", "database": "AGR" }, { "id": "SGD:S000001627", "url": "https://alliancegenome.org/gene/SGD:S000001627#orthology", "database": "AGR" }, { "id": "Q9VTL6", "url": "https://omabrowser.org/oma/group/Q9VTL6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9M9Y6-1", "protein_name": "DNA-directed RNA polymerase subunit", "gene_name": "NRPC7", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MFYLSELEHSLRVPPHLLNLPLEDAIKSVLQNVFLDKVLADLGLCVSIYDIKSVEGGFVLPGDGAATYKVGLRIVVFRPFVGEVIAAKFKESDANGLRLTLGFFDDIYVPAPLMPKPNRCEPDPYNRKQMIWVWEYGEPKEDYIVDDACQIKFRVESISYPSVPTERAEDAKPFAPMVVTGNMDDDGLGPVSWWDSYEQVDQEE", "length": 204 }, "evidence": [ { "id": "Q9VTL6", "url": "https://omabrowser.org/oma/group/Q9VTL6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9Y535-1", "protein_name": "DNA-directed RNA polymerase III subunit RPC8", "gene_name": "POLR3H", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFVLVEMVDTVRIPPWQFERKLNDSIAEELNKKLANKVVYNVGLCICLFDITKLEDAYVFPGDGASHTKVHFRCVVFHPFLDEILIGKIKGCSPEGVHVSLGFFDDILIPPESLQQPAKFDEAEQVWVWEYETEEGAHDLYMDTGEEIRFRVVDESFVDTSPTGPSSADATTSSEELPKKEAPYTLVGSISEPGLGLLSWWTSN", "length": 204 }, "evidence": [ { "id": "FB:FBgn0036188", "url": "https://alliancegenome.org/gene/FB:FBgn0036188#orthology", "database": "AGR" }, { "id": "MGI:1926179", "url": "https://alliancegenome.org/gene/MGI:1926179#orthology", "database": "AGR" }, { "id": "HGNC:30349", "url": "https://alliancegenome.org/gene/HGNC:30349#orthology", "database": "AGR" }, { "id": "RGD:1305889", "url": "https://alliancegenome.org/gene/RGD:1305889#orthology", "database": "AGR" }, { "id": "SGD:S000001627", "url": "https://alliancegenome.org/gene/SGD:S000001627#orthology", "database": "AGR" }, { "id": "Q9VTL6", "url": "https://omabrowser.org/oma/group/Q9VTL6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VTL6", "url": "https://www.uniprot.org/uniprotkb/Q9VTL6" } ], "pmid": "" }, { "name": "RNA polymerase III complex", "id": "GO:0005666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005666", "evidence": [ { "database": "UniProtKB", "id": "Q9VTL6", "url": "https://www.uniprot.org/uniprotkb/Q9VTL6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "Q9VTL6", "url": "https://www.uniprot.org/uniprotkb/Q9VTL6" } ], "pmid": "" }, { "name": "defense response to virus", "id": "GO:0051607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051607", "evidence": [ { "database": "UniProtKB", "id": "Q9VTL6", "url": "https://www.uniprot.org/uniprotkb/Q9VTL6" } ], "pmid": "" }, { "name": "transcription by RNA polymerase III", "id": "GO:0006383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006383", "evidence": [ { "database": "UniProtKB", "id": "Q9VTL6", "url": "https://www.uniprot.org/uniprotkb/Q9VTL6" } ], "pmid": "" }, { "name": "termination of RNA polymerase III transcription", "id": "GO:0006386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006386", "evidence": [ { "database": "UniProtKB", "id": "Q9VTL6", "url": "https://www.uniprot.org/uniprotkb/Q9VTL6" } ], "pmid": "" }, { "name": "transcription initiation at RNA polymerase III promoter", "id": "GO:0006384", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006384", "evidence": [ { "database": "UniProtKB", "id": "Q9VTL6", "url": "https://www.uniprot.org/uniprotkb/Q9VTL6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 202, "end_pos": 204, "annotation": "n_glycosylation_sequon" }, { "start_pos": 91, "end_pos": 93, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VTL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTL6" }, { "id": "PF08292", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08292" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RNA polymerase III subunit Rpc25", "eco_id": "ECO_0000259", "start_pos": 84, "end_pos": 212, "start_aa": "Val", "end_aa": "Trp", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q9VTL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTL6" }, { "id": "PF03876", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03876" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RNA polymerase Rpb7-like N-terminal", "eco_id": "ECO_0000259", "start_pos": 8, "end_pos": 64, "start_aa": "Lys", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 202, "end_pos": 204 }, { "start_pos": 91, "end_pos": 93 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VTM6-1", "uniprot_ac": "Q9VTM6", "uniprot_id": "CRIM_DROME", "mass": { "chemical_mass": 17744.0, "monoisotopic_mass": 17744.0 }, "refseq": { "ac": "NP_648500", "name": "crimpled", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648500" }, "gene_names": [ { "name": "crim", "type": "recommended", "evidence": [ { "id": "Q9VTM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTM6" } ] }, { "name": "CG6038", "type": "synonym", "evidence": [ { "id": "NP_648500", "database": "RefSeq", "url": 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"https://www.ncbi.nlm.nih.gov/protein/NP_648500" } ] }, { "name": "Protein crimpled", "type": "synonym", "evidence": [ { "id": "Q9VTM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTM6/entry#names_and_taxonomy" } ] }, { "name": "crim-PA", "type": "synonym", "evidence": [ { "id": "NP_648500", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648500" } ] }, { "name": "crimpled", "type": "synonym", "evidence": [ { "id": "NP_648500", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648500" } ] } ], "function": [ { "annotation": "Required for septate junction assembly possibly by organizing the preassembly and transport of septate junction proteins (PubMed:20570942). Involved in epithelial cell septate junction-mediated paracellular barrier functions of trachea, hindgut and salivary gland (PubMed:20570942).", "evidence": [ { "database": "UniProtKB", "id": "Q9VTM6", "url": "https://www.uniprot.org/uniprotkb/Q9VTM6#function" }, { "database": "PubMed", "id": "20570942", "url": "https://glygen.org/publication/PubMed/20570942" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VTM6", "url": "https://www.uniprot.org/uniprotkb/Q9VTM6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "crim", "url": "https://www.uniprot.org/uniprotkb/Q9VTM6", "locus": { "chromosome": "3L", "start_pos": 11710507, "end_pos": 11711386, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0036198", "url": "https://www.ensemblgenomes.org/id/FBgn0036198" } ] } } ], "crossref": [ { "id": "FB:FBgn0036198", "url": "https://alliancegenome.org/gene/FB:FBgn0036198", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "Q9VTM6", "url": "https://alphafold.ebi.ac.uk/entry/Q9VTM6", "database": "AlphaFoldDB", "categories": [] }, { "id": "FBgn0036198", "url": "https://bgee.org/?page=gene&gene_id=FBgn0036198", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd23591", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23591", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0036198", "url": "https://flybase.org/reports/FBgn0036198", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "39321", "url": "https://www.ncbi.nlm.nih.gov/gene/39321", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR031424", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031424", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050975", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050975", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG6038", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG6038", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TDTTFCF", "url": "https://omabrowser.org/oma/group/TDTTFCF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VTM6", "url": "https://www.orthodb.org/?gene=Q9VTM6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR33562", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33562", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR33562:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33562:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF17064", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17064", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q9VTM6", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q9VTM6", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_648500", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648500", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VTM6", "url": "https://www.uniprot.org/uniprotkb/Q9VTM6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VTM6-1", "url": "https://www.uniprot.org/uniprotkb/Q9VTM6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHYHTNLIAALLLAALIHEGSAIWCYRCTSATPGCAEKFNWRGIGFLGEHCPEPDDICVKVTERRGARETITRDCLSALSFRKDIPADKYEGCRPAAHDEKLANYVNHTIKEHDVRRDYYTDTTFCFCFLDHRCNGASGLQTSAVIGLLTLIPALLLR", "length": 158, "header": "sp|Q9VTM6-1|CRIM_DROME Isoform 1 of UPAR/Ly6 domain-containing protein crim OS=Drosophila melanogaster OX=7227 GN=crim PE=2 SV=1 CANONICAL=Q9VTM6-1" }, "isoforms": [ { "isoform_ac": "Q9VTM6-1", "url": "https://www.uniprot.org/uniprotkb/Q9VTM6/entry#Q9VTM6-1", "sequence": { "sequence": "MHYHTNLIAALLLAALIHEGSAIWCYRCTSATPGCAEKFNWRGIGFLGEHCPEPDDICVKVTERRGARETITRDCLSALSFRKDIPADKYEGCRPAAHDEKLANYVNHTIKEHDVRRDYYTDTTFCFCFLDHRCNGASGLQTSAVIGLLTLIPALLLR", "length": 158, "header": "sp|Q9VTM6-1|CRIM_DROME Isoform 1 of UPAR/Ly6 domain-containing protein crim OS=Drosophila melanogaster OX=7227 GN=crim PE=2 SV=1 CANONICAL=Q9VTM6-1" }, "locus": { "chromosome": "3L", "start_pos": 11710507, "end_pos": 11711386, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0076123", "url": "https://www.ensemblgenomes.org/id/FBtr0076123" }, { "database": "Ensembl Peptide", "id": "FBpp0075854", "url": "https://www.ensemblgenomes.org/id/FBpp0075854" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 107, "start_aa": "Asn", "end_pos": 107, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn107", "evidence": [ { "id": "Q9VTM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTM6#ptm_processing" }, { "id": "PRU00498", "database": "PROSITE-ProRule", "url": "https://prosite.expasy.org/rule/PRU00498" } ], "filter_code": "00100000000000000000.00010000000000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 32, "start_aa": "Thr", "end_pos": 32, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr32", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VTM6", "url": "https://www.uniprot.org/uniprotkb/Q9VTM6" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "A Drosophila full-length cDNA resource.", "journal": "Genome Biol.", "date": "2002", "authors": "Stapleton M, Carlson J, Brokstein P, Yu C, Champe M, George R, Guarin H, Kronmiller B, Pacleb J, Park S, Wan K, Rubin GM, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VTM6", "url": "https://www.uniprot.org/uniprotkb/Q9VTM6" } ], "reference": [ { "type": "PubMed", "id": "12537569", "url": "https://glygen.org/publication/PubMed/12537569" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VTM6", "url": "https://www.uniprot.org/uniprotkb/Q9VTM6" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "Crooked, coiled and crimpled are three Ly6-like proteins required for proper localization of septate junction components.", "journal": "Development (Cambridge, England)", "date": "2010-07", "authors": "Nilton Anna, Oshima Kenzi, Zare Fariba, Byri Sunitha, Nannmark Ulf, Nyberg Kevin G, Fehon Richard G, Uv Anne E", "evidence": [ { "database": "UniProtKB", "id": "Q9VTM6", "url": "https://www.uniprot.org/uniprotkb/Q9VTM6" } ], "reference": [ { "type": "PubMed", "id": "20570942", "url": "https://glygen.org/publication/PubMed/20570942" } ] } ], "pathway": [ { "id": "dme:Dmel_CG6038", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG6038", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "sleep", "id": "GO:0030431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030431", "evidence": [ { "database": "UniProtKB", "id": "Q9VTM6", "url": "https://www.uniprot.org/uniprotkb/Q9VTM6" } ], "pmid": "" }, { "name": "rhythmic process", "id": "GO:0048511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048511", "evidence": [ { "database": "UniProtKB", "id": "Q9VTM6", "url": "https://www.uniprot.org/uniprotkb/Q9VTM6" } ], "pmid": "" }, { "name": "regulation of synaptic transmission, cholinergic", "id": "GO:0032222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032222", "evidence": [ { "database": "UniProtKB", "id": "Q9VTM6", "url": "https://www.uniprot.org/uniprotkb/Q9VTM6" } ], "pmid": "" }, { "name": "septate junction assembly", "id": "GO:0019991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019991", "evidence": [ { "database": "UniProtKB", "id": "Q9VTM6", "url": "https://www.uniprot.org/uniprotkb/Q9VTM6" } ], "pmid": "" }, { "name": "liquid clearance, open tracheal system", "id": "GO:0035002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035002", "evidence": [ { "database": "UniProtKB", "id": "Q9VTM6", "url": "https://www.uniprot.org/uniprotkb/Q9VTM6" } ], "pmid": "" }, { "name": "regulation of tube size, open tracheal system", "id": "GO:0035151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035151", "evidence": [ { "database": "UniProtKB", "id": "Q9VTM6", "url": "https://www.uniprot.org/uniprotkb/Q9VTM6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "septate junction", "id": "GO:0005918", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005918", "evidence": [ { "database": "UniProtKB", "id": "Q9VTM6", "url": "https://www.uniprot.org/uniprotkb/Q9VTM6" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "Q9VTM6", "url": "https://www.uniprot.org/uniprotkb/Q9VTM6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 107, "end_pos": 109, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q9VTM6-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 158, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q9VTM6-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q9VTM6" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [ 107 ], "o_linked_sites": [ 32 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 107, "end_pos": 109 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { 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0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VTS1-1", "uniprot_ac": "Q9VTS1", "uniprot_id": "Q9VTS1_DROME", "mass": { "chemical_mass": 32822.0, "monoisotopic_mass": 32822.0 }, "refseq": { "ac": "NP_648536", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648536" }, "gene_names": [ { "name": "Dmel\\CG6931", "type": "recommended", "evidence": [ { "id": "Q9VTS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTS1" } ] }, { "name": "CG6931", "type": "synonym", "evidence": [ { "id": "NP_648536", "database": "RefSeq", "url": 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"https://www.ncbi.nlm.nih.gov/protein/NP_648536" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VTS1", "url": "https://www.uniprot.org/uniprotkb/Q9VTS1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG6931", "url": "https://www.uniprot.org/uniprotkb/Q9VTS1", "locus": { "chromosome": "3L", "start_pos": 11992000, "end_pos": 11990736, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0036236", "url": "https://www.ensemblgenomes.org/id/FBgn0036236" } ] } } ], "crossref": [ { "id": "FB:FBgn0036236", "url": "https://alliancegenome.org/gene/FB:FBgn0036236", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0036236", "url": "https://bgee.org/?page=gene&gene_id=FBgn0036236", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0036236", "url": "https://flybase.org/reports/FBgn0036236", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "39363", "url": "https://www.ncbi.nlm.nih.gov/gene/39363", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018958", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018958", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039231", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039231", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG6931", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG6931", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WQFLAET", "url": "https://omabrowser.org/oma/group/WQFLAET/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VTS1", "url": "https://www.orthodb.org/?gene=Q9VTS1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31854", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31854", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31854:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31854:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "NP_648536", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648536", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VTS1", "url": "https://www.uniprot.org/uniprotkb/Q9VTS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VTS1-1", "url": "https://www.uniprot.org/uniprotkb/Q9VTS1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMNKKLSPEDAFYENLTLGLIRTLSNVPRVCNVTLERRQPLNACQLVNWEQRHCVYLPEDMKKFYLSSDGFILNWSYQYAPNDIRRVGHIHFPHLLQVTLLRENIETTSSHSSNSTAVPNSNSDVVGAAGSSQSLPAPIATGKDKWGNATPIITAKSKIFEINNVNEVAKVCMLYESTSSNNPKFYLLELSTLSWQFLADTFSEYLRMAIAHLGLPYWELCFSTCGLPSWTEQLFLLLAPHLLEEHEPRRGRVLNPACEHPYNIIDPNIFRGKPKSVAKATATSTKQNHK", "length": 290, "header": "tr|Q9VTS1-1|Q9VTS1_DROME Isoform 1 of Knr4/Smi1-like domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG6931 PE=4 SV=1 CANONICAL=Q9VTS1-1" }, "isoforms": [ { "isoform_ac": "Q9VTS1-1", "url": "https://www.uniprot.org/uniprotkb/Q9VTS1/entry#Q9VTS1-1", "sequence": { "sequence": "MMNKKLSPEDAFYENLTLGLIRTLSNVPRVCNVTLERRQPLNACQLVNWEQRHCVYLPEDMKKFYLSSDGFILNWSYQYAPNDIRRVGHIHFPHLLQVTLLRENIETTSSHSSNSTAVPNSNSDVVGAAGSSQSLPAPIATGKDKWGNATPIITAKSKIFEINNVNEVAKVCMLYESTSSNNPKFYLLELSTLSWQFLADTFSEYLRMAIAHLGLPYWELCFSTCGLPSWTEQLFLLLAPHLLEEHEPRRGRVLNPACEHPYNIIDPNIFRGKPKSVAKATATSTKQNHK", "length": 290, "header": "tr|Q9VTS1-1|Q9VTS1_DROME Isoform 1 of Knr4/Smi1-like domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG6931 PE=4 SV=1 CANONICAL=Q9VTS1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VTS1", "url": "https://www.uniprot.org/uniprotkb/Q9VTS1" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VTS1", "url": "https://www.uniprot.org/uniprotkb/Q9VTS1" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VTS1", "url": "https://www.uniprot.org/uniprotkb/Q9VTS1" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VTS1", "url": "https://www.uniprot.org/uniprotkb/Q9VTS1" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VTS1", "url": "https://www.uniprot.org/uniprotkb/Q9VTS1" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VTS1", "url": "https://www.uniprot.org/uniprotkb/Q9VTS1" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VTS1", "url": "https://www.uniprot.org/uniprotkb/Q9VTS1" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VTS1", "url": "https://www.uniprot.org/uniprotkb/Q9VTS1" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VTS1", "url": "https://www.uniprot.org/uniprotkb/Q9VTS1" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VTS1", "url": "https://www.uniprot.org/uniprotkb/Q9VTS1" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VTS1", "url": "https://www.uniprot.org/uniprotkb/Q9VTS1" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG6931", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG6931", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YB54-1", "protein_name": "Tubulin polyglutamylase complex subunit 2", "gene_name": "TPGS2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEEKPSAGIRPHLDKLTLGVTRILETSPGVSDVTLVEKEPADRHAIISWEQKNACILPEDLKNFYLMTDGFQMTWSVKIDDTPMPLGSMVINSISKLCRLGGSSMYTVPNAPSLADLEDDTDEEGKVLLTGNEDKPEKPHFDSRSLIFELDPCNGNGKVCLVYRHTKPVVSPDTEIWFLDRALYWHFLTKTFTAYYRLLITHLGLPQWQYAFTSYGVSPQAKQWFNMYKPITINTTLLSEEADSFVNKLDPSKIFKSKNKTPVMKKKQPSQPAGVQKSNTSMPSTKTSSLAGNSSRKRDPQI", "length": 302 }, "evidence": [ { "id": "Q9VTS1", "url": "https://omabrowser.org/oma/group/Q9VTS1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "I3LA68-1", "protein_name": "Tubulin polyglutamylase complex subunit 2", "gene_name": "TPGS2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEETPPPLLGSSKPHLEKLTLGITRILESSPGVTEVTIVEKVPAERHMISSWEQKNNCLLPEDLKNFYLMTNGFHMTWSVKLDEHTIPLGSMAINSISKLTQLNQSSMYSLPNAPTLADLEDDTQEAGENQPEKPHFDSRSVIFELDPCNGNGKVCLVYKRGKPALAQDSEIWFLDRALYWHFLTDTFTAYYRLLITHLGLPQWQYAFTSYGISPQAKQWFNMYKPITYNTNLLTEETDSFVNKLDPSKVFKSKNKTLIPKKKGPPQPAGGQKGPSGPPSTSKSSSGSGNPVRK", "length": 294 }, "evidence": [ { "id": "Q9VTS1", "url": "https://omabrowser.org/oma/group/Q9VTS1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q66JT5-1", "protein_name": "Tubulin polyglutamylase complex subunit 2", "gene_name": "Tpgs2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEETTPPLQAGSKPHLEKLTLGVTRILESSPGVTEVSIIEKLPAERHVISSWEQKNNCVMPEDVRNFYLMTNGFHMTWSVKLDEHIIPLGSMVINGISKLTQLIQSSVYSLPNAPTLADLEDDTQEGNEDHQLEKPHFDCRSAIFELDSCNGNGKVCLVYKNGKPGLAHDTEIWFLDRALYWHFLTDTFIAYYRLLITHLGLPQWQYAFTSYGISPQAKQWFSMYKPITYNTSLLTEESDNFANKLDPSKVFKSKNKILIPKKKGPVPPASGQKGPGPLPPPTSKPTTGSGNPVRK", "length": 296 }, "evidence": [ { "id": "RGD:1310571", "url": "https://alliancegenome.org/gene/RGD:1310571#orthology", "database": "AGR" }, { "id": "MGI:1913898", "url": "https://alliancegenome.org/gene/MGI:1913898#orthology", "database": "AGR" }, { "id": "HGNC:24561", "url": "https://alliancegenome.org/gene/HGNC:24561#orthology", "database": "AGR" }, { "id": "FB:FBgn0036236", "url": "https://alliancegenome.org/gene/FB:FBgn0036236#orthology", "database": "AGR" }, { "id": "Q9VTS1", "url": "https://omabrowser.org/oma/group/Q9VTS1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q68CL5-2", "protein_name": "Tubulin polyglutamylase complex subunit 2", "gene_name": "TPGS2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEEASSPGLGCSKPHLEKLTLGITRILESSPGVTEVTIIEKPPAERHMISSWEQKNNCVMPEDVKNFYLMTNGFHMTWSVKLDEHIIPLGSMAINSISKLTQLTQSSMYSLPNAPTLADLEDDTHEASDDQPEKPHFDSRSVIFELDSCNGSGKVCLVYKSGKPALAEDTEIWFLDRALYWHFLTDTFTAYYRLLITHLGLPQWQYAFTSYGISPQAKQWFSMYKPITYNTNLLTEETDSFVNKLDPSKVFKSKNKIVIPKKKGPVQPAGGQKGPSGPSGPSTSSTSKSSSGSGNPTRK", "length": 300 }, "evidence": [ { "id": "RGD:1310571", "url": "https://alliancegenome.org/gene/RGD:1310571#orthology", "database": "AGR" }, { "id": "MGI:1913898", "url": "https://alliancegenome.org/gene/MGI:1913898#orthology", "database": "AGR" }, { "id": "HGNC:24561", "url": "https://alliancegenome.org/gene/HGNC:24561#orthology", "database": "AGR" }, { "id": "FB:FBgn0036236", "url": "https://alliancegenome.org/gene/FB:FBgn0036236#orthology", "database": "AGR" }, { "id": "Q9VTS1", "url": "https://omabrowser.org/oma/group/Q9VTS1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6AXS8-1", "protein_name": "Tubulin polyglutamylase complex subunit 2", "gene_name": "Tpgs2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEETPPPMQAGSKPHLEKLTLGVTRILESSPGVTEVSIIEKLPAERHMISSWEQKNNCVMPEDVRNFYLMTNGFHMTWSVKLDDHIIPLGSMVINGISKLTQLIQSSVYSLPNAPTLADLEDDSQEGNEDHQLEKPHFDCRSAIFELDSCGGNGKVCLVYKNGKPGLAHDTEIWFLDRALYWHFLTDTFTAYYRLLITHLGLPQWQYAFTSYGISPQAKQWFSMYKPITYNTSLLTEEPDTFVNKLDPSKVFKSKNKILIPKKKGPVQPVSGQKGPGPLAPPTSKPSAGCGNPVRK", "length": 296 }, "evidence": [ { "id": "RGD:1310571", "url": "https://alliancegenome.org/gene/RGD:1310571#orthology", "database": "AGR" }, { "id": "MGI:1913898", "url": "https://alliancegenome.org/gene/MGI:1913898#orthology", "database": "AGR" }, { "id": "HGNC:24561", "url": "https://alliancegenome.org/gene/HGNC:24561#orthology", "database": "AGR" }, { "id": "FB:FBgn0036236", "url": "https://alliancegenome.org/gene/FB:FBgn0036236#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 114, "end_pos": 116, "annotation": "n_glycosylation_sequon" }, { "start_pos": 148, "end_pos": 150, "annotation": "n_glycosylation_sequon" }, { "start_pos": 15, "end_pos": 17, "annotation": "n_glycosylation_sequon" }, { "start_pos": 32, "end_pos": 34, "annotation": "n_glycosylation_sequon" }, { "start_pos": 74, "end_pos": 76, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VTS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTS1" }, { "id": "SM00860", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00860" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Knr4/Smi1-like", "eco_id": "ECO_0000259", "start_pos": 40, "end_pos": 208, "start_aa": "Pro", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 114, "end_pos": 116 }, { "start_pos": 148, "end_pos": 150 }, { "start_pos": 15, "end_pos": 17 }, { "start_pos": 32, "end_pos": 34 }, { "start_pos": 74, "end_pos": 76 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VTU2-1", "uniprot_ac": "Q9VTU2", "uniprot_id": "Q9VTU2_DROME", "mass": { "chemical_mass": 22030.0, "monoisotopic_mass": 22030.0 }, "refseq": { "ac": "NP_001261742", "name": "NADH dehydrogenase (ubiquinone) SGDH subunit, isoform B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261742" }, "gene_names": [ { "name": "ND-SGDH", "type": "recommended", "evidence": [ { "id": "Q9VTU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTU2" } ] }, { "name": "CG9762", "type": "synonym", "evidence": [ { "id": "NP_001261742", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261742" }, { "id": "Q9VTU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTU2" } ] }, { "name": "Dmel\\CG9762", "type": "synonym", "evidence": [ { "id": "NP_001261742", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261742" }, { "id": "Q9VTU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTU2" } ] }, { "name": "Dmel_CG9762", "type": "synonym", "evidence": [ { "id": "Q9VTU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTU2" } ] }, { "name": "ND-SGDH", "type": "synonym", "evidence": [ { "id": "NP_001261742", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261742" } ] }, { "name": "NDUFB5", "type": "synonym", "evidence": [ { "id": "NP_001261742", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261742" }, { "id": "Q9VTU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTU2" } ] }, { "name": "NISM", "type": "synonym", "evidence": [ { "id": "NP_001261742", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261742" }, { "id": "Q9VTU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTU2" } ] }, { "name": "Q9VTU2", "type": "synonym", "evidence": [ { "id": "NP_001261742", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261742" }, { "id": "Q9VTU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTU2" } ] }, { "name": "dND-SGDH", "type": "synonym", "evidence": [ { "id": "NP_001261742", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261742" }, { "id": "Q9VTU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTU2" } ] }, { "name": "dNDUFB5", "type": "synonym", "evidence": [ { "id": "NP_001261742", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261742" }, { "id": "Q9VTU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTU2" } ] }, { "name": "l(3)neo18", "type": "synonym", "evidence": [ { "id": "NP_001261742", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261742" }, { "id": "Q9VTU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTU2" } ] } ], "protein_names": [ { "name": "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial", "type": "recommended", "evidence": [ { "id": "Q9VTU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTU2/entry#names_and_taxonomy" } ] }, { "name": "CG9762-PB", "type": "synonym", "evidence": [ { "id": "NP_001261742", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261742" } ] }, { "name": "Complex I-SGDH", "type": "synonym", "evidence": [ { "id": "Q9VTU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTU2/entry#names_and_taxonomy" } ] }, { "name": "NADH dehydrogenase (ubiquinone) SGDH subunit, isoform B", "type": "synonym", "evidence": [ { "id": "NP_001261742", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261742" } ] }, { "name": "NADH ubiquinone oxidoreductase SGDH", "type": "synonym", "evidence": [ { "id": "NP_001261742", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261742" } ] }, { "name": "NADH-ubiquinone oxidoreductase SGDH subunit", "type": "synonym", "evidence": [ { "id": "NP_001261742", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261742" }, { "id": "Q9VTU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTU2/entry#names_and_taxonomy" } ] }, { "name": "NADH:ubiquinone oxidoreductase SGDH subunit", "type": "synonym", "evidence": [ { "id": "NP_001261742", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261742" } ] }, { "name": "ND-SGDH-PB", "type": "synonym", "evidence": [ { "id": "NP_001261742", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261742" } ] }, { "name": "lethal (3) neo18", "type": "synonym", "evidence": [ { "id": "NP_001261742", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261742" } ] } ], "function": [ { "annotation": "Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.", "evidence": [ { "database": "UniProtKB", "id": "Q9VTU2", "url": "https://www.uniprot.org/uniprotkb/Q9VTU2#function" }, { "database": "UniProtKB", "id": "ARBA00003195", "url": "https://www.uniprot.org/uniprotkb/ARBA00003195#function" } ] } ], "disease": [ { "disease_id": "DOID:9408", "recommended_name": { "id": "DOID:9408", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9408", "name": "acute myocardial infarction", "description": "" }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "9408", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9408" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VTU2", "url": "https://www.uniprot.org/uniprotkb/Q9VTU2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "ND-SGDH", "url": "https://www.uniprot.org/uniprotkb/Q9VTU2", "locus": { "chromosome": "3L", "start_pos": 12137496, "end_pos": 12138584, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0011455", "url": "https://www.ensemblgenomes.org/id/FBgn0011455" } ] } } ], "crossref": [ { "id": "FB:FBgn0011455", "url": "https://alliancegenome.org/gene/FB:FBgn0011455", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0011455", "url": "https://bgee.org/?page=gene&gene_id=FBgn0011455", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0011455", "url": "https://flybase.org/reports/FBgn0011455", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "46260", "url": "https://www.ncbi.nlm.nih.gov/gene/46260", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "8B9Z", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8B9Z&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8BA0", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8BA0&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ESW", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ESW&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8ESZ", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8ESZ&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "Q9VTU2", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VTU2*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR019173", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019173", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG9762", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG9762", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HHHMTIK", "url": "https://omabrowser.org/oma/group/HHHMTIK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VTU2", "url": "https://www.orthodb.org/?gene=Q9VTU2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13178", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13178", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13178:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13178:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00008b9z", "url": "https://www.rcsb.org/structure/pdb_00008b9z", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008ba0", "url": "https://www.rcsb.org/structure/pdb_00008ba0", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008esw", "url": "https://www.rcsb.org/structure/pdb_00008esw", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008esz", "url": "https://www.rcsb.org/structure/pdb_00008esz", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8B9Z", "url": "https://www.rcsb.org/structure/8B9Z", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8BA0", "url": "https://www.rcsb.org/structure/8BA0", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ESW", "url": "https://www.rcsb.org/structure/8ESW", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8ESZ", "url": "https://www.rcsb.org/structure/8ESZ", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF09781", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09781", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-611105", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-611105", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-6799198", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6799198", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001261742", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261742", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VTU2", "url": "https://www.uniprot.org/uniprotkb/Q9VTU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VTU2-1", "url": "https://www.uniprot.org/uniprotkb/Q9VTU2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVGWSRLLSPAAKFASYRAVLQEPACRNALHQQLRRMGGDHGHHQMIIKPSRFQWDKFKDLLHFYVMLGVIPVTALVLYANIFVGPAQLAEIPEGYEPKHWEYEKHPISRFISRYILNSDQQNYEKSLHYLYEENEKAQIRLLEDEVRRKMSERNDYQAYYYRPSVAKYHRISKEAADELEALRGD", "length": 186, "header": "tr|Q9VTU2-1|Q9VTU2_DROME Isoform 1 of NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial OS=Drosophila melanogaster OX=7227 GN=ND-SGDH PE=1 SV=1 CANONICAL=Q9VTU2-1" }, "isoforms": [ { "isoform_ac": "Q9VTU2-1", "url": "https://www.uniprot.org/uniprotkb/Q9VTU2/entry#Q9VTU2-1", "sequence": { "sequence": "MVGWSRLLSPAAKFASYRAVLQEPACRNALHQQLRRMGGDHGHHQMIIKPSRFQWDKFKDLLHFYVMLGVIPVTALVLYANIFVGPAQLAEIPEGYEPKHWEYEKHPISRFISRYILNSDQQNYEKSLHYLYEENEKAQIRLLEDEVRRKMSERNDYQAYYYRPSVAKYHRISKEAADELEALRGD", "length": 186, "header": "tr|Q9VTU2-1|Q9VTU2_DROME Isoform 1 of NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial OS=Drosophila melanogaster OX=7227 GN=ND-SGDH PE=1 SV=1 CANONICAL=Q9VTU2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VTU2", "url": "https://www.uniprot.org/uniprotkb/Q9VTU2" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VTU2", "url": "https://www.uniprot.org/uniprotkb/Q9VTU2" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VTU2", "url": "https://www.uniprot.org/uniprotkb/Q9VTU2" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VTU2", "url": "https://www.uniprot.org/uniprotkb/Q9VTU2" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VTU2", "url": "https://www.uniprot.org/uniprotkb/Q9VTU2" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VTU2", "url": "https://www.uniprot.org/uniprotkb/Q9VTU2" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VTU2", "url": "https://www.uniprot.org/uniprotkb/Q9VTU2" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VTU2", "url": "https://www.uniprot.org/uniprotkb/Q9VTU2" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VTU2", "url": "https://www.uniprot.org/uniprotkb/Q9VTU2" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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Classification" ] }, { "id": "IPR027430", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027430", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050125", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050125", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG5638", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG5638", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IHYRDKY", "url": "https://omabrowser.org/oma/group/IHYRDKY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VTU7", "url": "https://www.orthodb.org/?gene=Q9VTU7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24240", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24240", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-391908", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-391908", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-418594", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-418594", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-5620922", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-5620922", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_524035", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524035", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VTU7", "url": "https://www.uniprot.org/uniprotkb/Q9VTU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VTU7-1", "url": "https://www.uniprot.org/uniprotkb/Q9VTU7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAIIMTTLPNLTTDAGDSSFWLTGALSLSEMLANSSHSHSTGSTTSTAGSSATESSAVNVGKDHDKHVNDSVSTGLSNYSNYPSYIHYRDKYDLSYIAKVNPFWLQFEPPKSSTFLIMAALYCLISVVGCVGNAFVIFMFANRKSLRTPANILVMNLAICDFLMLIKCPIAIYNNIKEGPALGDIACRLYGFVGGLSGTCAIGTLTAIALDRYNVVVHPLQPLRRCSRLRSYLIILLIWCYSFLFAVMPALDIGLSVYVPEGFLTTCSFDYLNKEMPARIFMALFFVAAYCIPLTSIVYSYFYILKVVFTASRIQSNKDKAKTEQKLAFIVAAIIGLWFLAWSPYAIVAMMGVFGLERHITPLGSMIPALFCKTAACVDPYLYAATHPRFRVEVRMLFYGRGVLRRVSTTRSSYMTRSRSSFTHRLRTSTTGEGGMGDHRMENYLMNNNLMMVPEETEENEEIVVVAEINNSISSVMEQSKF", "length": 483, "header": "tr|Q9VTU7-1|Q9VTU7_DROME Isoform 1 of Rhodopsin 7 OS=Drosophila melanogaster OX=7227 GN=Rh7 PE=3 SV=2 CANONICAL=Q9VTU7-1" }, "isoforms": [ { "isoform_ac": "Q9VTU7-1", "url": "https://www.uniprot.org/uniprotkb/Q9VTU7/entry#Q9VTU7-1", "sequence": { "sequence": "MEAIIMTTLPNLTTDAGDSSFWLTGALSLSEMLANSSHSHSTGSTTSTAGSSATESSAVNVGKDHDKHVNDSVSTGLSNYSNYPSYIHYRDKYDLSYIAKVNPFWLQFEPPKSSTFLIMAALYCLISVVGCVGNAFVIFMFANRKSLRTPANILVMNLAICDFLMLIKCPIAIYNNIKEGPALGDIACRLYGFVGGLSGTCAIGTLTAIALDRYNVVVHPLQPLRRCSRLRSYLIILLIWCYSFLFAVMPALDIGLSVYVPEGFLTTCSFDYLNKEMPARIFMALFFVAAYCIPLTSIVYSYFYILKVVFTASRIQSNKDKAKTEQKLAFIVAAIIGLWFLAWSPYAIVAMMGVFGLERHITPLGSMIPALFCKTAACVDPYLYAATHPRFRVEVRMLFYGRGVLRRVSTTRSSYMTRSRSSFTHRLRTSTTGEGGMGDHRMENYLMNNNLMMVPEETEENEEIVVVAEINNSISSVMEQSKF", "length": 483, "header": "tr|Q9VTU7-1|Q9VTU7_DROME Isoform 1 of Rhodopsin 7 OS=Drosophila melanogaster OX=7227 GN=Rh7 PE=3 SV=2 CANONICAL=Q9VTU7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VTU7", "url": "https://www.uniprot.org/uniprotkb/Q9VTU7" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VTU7", "url": "https://www.uniprot.org/uniprotkb/Q9VTU7" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VTU7", "url": "https://www.uniprot.org/uniprotkb/Q9VTU7" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VTU7", "url": "https://www.uniprot.org/uniprotkb/Q9VTU7" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VTU7", "url": "https://www.uniprot.org/uniprotkb/Q9VTU7" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VTU7", "url": "https://www.uniprot.org/uniprotkb/Q9VTU7" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VTU7", "url": "https://www.uniprot.org/uniprotkb/Q9VTU7" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VTU7", "url": "https://www.uniprot.org/uniprotkb/Q9VTU7" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VTU7", "url": "https://www.uniprot.org/uniprotkb/Q9VTU7" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VTU7", "url": "https://www.uniprot.org/uniprotkb/Q9VTU7" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VTU7", "url": "https://www.uniprot.org/uniprotkb/Q9VTU7" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG5638", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG5638", "resource": "KEGG Pathway" }, { "id": "R-DME-391908", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-391908", "resource": "Reactome", "description": "Prostanoid ligand receptors" }, { "id": "R-DME-418594", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-418594", "resource": "Reactome", "description": "G alpha (i) signalling events" }, { "id": "R-DME-5620922", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-5620922", "resource": "Reactome", "description": "BBSome-mediated cargo-targeting to cilium" } ], "orthologs": [ { "uniprot_canonical_ac": "O01668-1", "protein_name": "Opsin Rh6", "gene_name": "Rh6", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MASLHPPSFAYMRDGRNLSLAESVPAEIMHMVDPYWYQWPPLEPMWFGIIGFVIAILGTMSLAGNFIVMYIFTSSKGLRTPSNMFVVNLAFSDFMMMFTMFPPVVLNGFYGTWIMGPFLCELYGMFGSLFGCVSIWSMTLIAYDRYCVIVKGMARKPLTATAAVLRLMVVWTICGAWALMPLFGWNRYVPEGNMTACGTDYFAKDWWNRSYIIVYSLWVYLTPLLTIIFSYWHIMKAVAAHEKAMREQAKKMNVASLRNSEADKSKAIEIKLAKVALTTISLWFFAWTPYTIINYAGIFESMHLSPLSTICGSVFAKANAVCNPIVYGLSHPKYKQVLREKMPCLACGKDDLTSDSRTQATAEISESQA", "length": 369 }, "evidence": [ { "id": "HGNC:14449", "url": "https://alliancegenome.org/gene/HGNC:14449#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070111-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070111-2#orthology", "database": "AGR" }, { "id": "MGI:1353425", "url": "https://alliancegenome.org/gene/MGI:1353425#orthology", "database": "AGR" }, { "id": "RGD:621701", "url": "https://alliancegenome.org/gene/RGD:621701#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P04950-1", "protein_name": "Opsin Rh3", "gene_name": "Rh3", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MESGNVSSSLFGNVSTALRPEARLSAETRLLGWNVPPEELRHIPEHWLTYPEPPESMNYLLGTLYIFFTLMSMLGNGLVIWVFSAAKSLRTPSNILVINLAFCDFMMMVKTPIFIYNSFHQGYALGHLGCQIFGIIGSYTGIAAGATNAFIAYDRFNVITRPMEGKMTHGKAIAMIIFIYMYATPWVVACYTETWGRFVPEGYLTSCTFDYLTDNFDTRLFVACIFFFSFVCPTTMITYYYSQIVGHVFSHEKALRDQAKKMNVESLRSNVDKNKETAEIRIAKAAITICFLFFCSWTPYGVMSLIGAFGDKTLLTPGATMIPACACKMVACIDPFVYAISHPRYRMELQKRCPWLALNEKAPESSAVASTSTTQEPQQTTAA", "length": 383 }, "evidence": [ { "id": "HGNC:14449", "url": "https://alliancegenome.org/gene/HGNC:14449#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070111-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070111-2#orthology", "database": "AGR" }, { "id": "MGI:1353425", "url": "https://alliancegenome.org/gene/MGI:1353425#orthology", "database": "AGR" }, { "id": "RGD:621701", "url": "https://alliancegenome.org/gene/RGD:621701#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P06002-1", "protein_name": "Opsin Rh1", "gene_name": "ninaE", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MESFAVAAAQLGPHFAPLSNGSVVDKVTPDMAHLISPYWNQFPAMDPIWAKILTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITNTPMMGINLYFETWVLGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAGRPMTIPLALGKIAYIWFMSSIWCLAPAFGWSRYVPEGNLTSCGIDYLERDWNPRSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKKMNVKSLRSSEDAEKSAEGKLAKVALVTITLWFMAWTPYLVINCMGLFKFEGLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCVFGKVDDGKSSDAQSQATASEAESKA", "length": 373 }, "evidence": [ { "id": "HGNC:14449", "url": "https://alliancegenome.org/gene/HGNC:14449#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070111-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070111-2#orthology", "database": "AGR" }, { "id": "MGI:1353425", "url": "https://alliancegenome.org/gene/MGI:1353425#orthology", "database": "AGR" }, { "id": "RGD:621701", "url": "https://alliancegenome.org/gene/RGD:621701#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P08099-1", "protein_name": "Opsin Rh2", "gene_name": "Rh2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MERSHLPETPFDLAHSGPRFQAQSSGNGSVLDNVLPDMAHLVNPYWSRFAPMDPMMSKILGLFTLAIMIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQSPVMIINFYYETWVLGPLWCDIYAGCGSLFGCVSIWSMCMIAFDRYNVIVKGINGTPMTIKTSIMKILFIWMMAVFWTVMPLIGWSAYVPEGNLTACSIDYMTRMWNPRSYLITYSLFVYYTPLFLICYSYWFIIAAVAAHEKAMREQAKKMNVKSLRSSEDCDKSAEGKLAKVALTTISLWFMAWTPYLVICYFGLFKIDGLTPLTTIWGATFAKTSAVYNPIVYGISHPKYRIVLKEKCPMCVFGNTDEPKPDAPASDTETTSEADSKA", "length": 381 }, "evidence": [ { "id": "HGNC:14449", "url": "https://alliancegenome.org/gene/HGNC:14449#orthology", "database": "AGR" }, { "id": "MGI:1353425", "url": "https://alliancegenome.org/gene/MGI:1353425#orthology", "database": "AGR" }, { "id": "RGD:621701", "url": "https://alliancegenome.org/gene/RGD:621701#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P08255-1", "protein_name": "Opsin Rh4", "gene_name": "Rh4", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEPLCNASEPPLRPEARSSGNGDLQFLGWNVPPDQIQYIPEHWLTQLEPPASMHYMLGVFYIFLFCASTVGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLKAPIFIYNSFHRGFALGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNRNMTFTKAVIMNIIIWLYCTPWVVLPLTQFWDRFVPEGYLTSCSFDYLSDNFDTRLFVGTIFFFSFVCPTLMILYYYSQIVGHVFSHEKALREQAKKMNVESLRSNVDKSKETAEIRIAKAAITICFLFFVSWTPYGVMSLIGAFGDKSLLTPGATMIPACTCKLVACIDPFVYAISHPRYRLELQKRCPWLGVNEKSGEISSAQSTTTQEQQQTTAA", "length": 378 }, "evidence": [ { "id": "HGNC:14449", "url": "https://alliancegenome.org/gene/HGNC:14449#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070111-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070111-2#orthology", "database": "AGR" }, { "id": "MGI:1353425", "url": 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"https://alliancegenome.org/gene/MGI:1353425#orthology", "database": "AGR" }, { "id": "RGD:621701", "url": "https://alliancegenome.org/gene/RGD:621701#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q1JPS6-1", "protein_name": "Melanopsin-like", "gene_name": "opn4l", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSHHSSWRGHHCAPGDINCTAGFKESLGSRNYKLLHVPVHGPTHSHHHDPPHPFPTVDVPDHAHYIIGSVILIVGITGVIGNALVVYVFCRSRTLRTAGNMFIVNLAVADFLMSVTQSPVFFAASLHRRWVFGERPCELYAFCGALFGICSMMTLTAIAADRCLAITQPLALVSRVSRRKAGAVLVVVWLYSLGWSLPPFFGWSAYVPEGLQTSCSWDYMTFTPSVRAYTILLFVFVFFIPLGIIGSCYFAIFQTIRAAGKEIRELDCGETHKVYERMQNEWKMAKVALVVIVLFIISWSPYSVVALTATAGYSHFLTPYMNSVPAVIAKASAIHNPIIYAITHPKYRVAIARYIPVLRPILRVKEKDLRSSFSSGSVSSRRPTLTSQCSLGVSMGNAARANGRWGKTRLSSASDSDSCWTESEADGSSVSSLTFGRRVSTEISTDTVILSSGSSVSNASGQKSERAHKVISVPVPSITFETDAADGESLSDGKALLGGN", "length": 500 }, "evidence": [ { "id": "HGNC:14449", "url": "https://alliancegenome.org/gene/HGNC:14449#orthology", "database": "AGR" }, { "id": "MGI:1353425", "url": "https://alliancegenome.org/gene/MGI:1353425#orthology", "database": "AGR" }, { "id": "RGD:621701", "url": "https://alliancegenome.org/gene/RGD:621701#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2KNE5-1", "protein_name": "Melanopsin-A", "gene_name": "opn4a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMSGAAHSVRKGISCPTQDPNCTRIVESLSAWNDSVMSAYRLVDLPPTTTTTTSVAMVEESVYPFPTVDVPDHAHYTIGAVILTVGITGMLGNFLVIYAFSRSRTLRTPANLFIINLAITDFLMCATQAPIFFTTSMHKRWIFGEKGCELYAFCGALFGICSMITLMVIAVDRYFVITRPLASIGVLSQKRALLILLVAWVYSLGWSLPPFFGWSAYVPEGLLTSCTWDYMTFTPSVRAYTMLLFIFVFFIPLIVIIYCYFFIFRSIRTTNEAVGKINGDNKRDSMKRFQRLKNEWKMAKIALIVILMYVISWSPYSTVALTAFAGYSDFLTPYMNSVPAVIAKASAIHNPIIYAITHPKYRLAIAKYIPCLRLLLCVPKRDLHSFHSSLMSTRRSTVTSQSSDMSGRFRRTSTGKSRLSSASDSESGWTDTEADLSSMSSRPASRQVSCDISKDTAEMPDFKPCNSSSFKSKLKSHDSGIFEKSSSDVDDVSVAGIIQPDRTLTNAGDITDVPISRGAIGRIPSIVITSESSSLLPSVRPTYRISRSNVSTVGTNPARRDSRGGVQQGAAHLSNAAETPESGHIDNHRPQYL", "length": 593 }, "evidence": [ { "id": "HGNC:14449", "url": "https://alliancegenome.org/gene/HGNC:14449#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070111-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070111-2#orthology", "database": "AGR" }, { "id": "MGI:1353425", "url": "https://alliancegenome.org/gene/MGI:1353425#orthology", "database": "AGR" }, { "id": "RGD:621701", "url": 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"https://alliancegenome.org/gene/HGNC:14449#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070111-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070111-2#orthology", "database": "AGR" }, { "id": "MGI:1353425", "url": "https://alliancegenome.org/gene/MGI:1353425#orthology", "database": "AGR" }, { "id": "RGD:621701", "url": "https://alliancegenome.org/gene/RGD:621701#orthology", "database": "AGR" }, { "id": "FB:FBgn0036260", "url": "https://alliancegenome.org/gene/FB:FBgn0036260#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9QXZ9-1", "protein_name": "Melanopsin", "gene_name": "Opn4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSPSGPRVLSSLTQDPSFTTSPALQGIWNGTQNVSVRAQLLSVSPTTSAHQAAAWVPFPTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRNRGLRTPANMFIINLAVSDFLMSVTQAPVFFASSLYKKWLFGETGCEFYAFCGAVFGITSMITLTAIAMDRYLVITRPLATIGRGSKRRTALVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMTFTPQVRAYTMLLFCFVFFLPLLIIIFCYIFIFRAIRETGRACEGCGESPLRQRRQWQRLQSEWKMAKVALIVILLFVLSWAPYSTVALVAFAGYSHILTPYMSSVPAVIAKASAIHNPIIYAITHPKYRVAIAQHLPCLGVLLGVSGQRSHPSLSYRSTHRSTLSSQSSDLSWISGRKRQESLGSESEVGWTDTETTAAWGAAQQASGQSFCSQNLEDGELKASSSPQVQRSKTPKVPGPSTCRPMKGQGARPSSLRGDQKGRLAVCTGLSECPHPHTSQFPLAFLEDDVTLRHL", "length": 521 }, "evidence": [ { "id": "HGNC:14449", "url": "https://alliancegenome.org/gene/HGNC:14449#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070111-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070111-2#orthology", "database": "AGR" }, { "id": "MGI:1353425", "url": "https://alliancegenome.org/gene/MGI:1353425#orthology", "database": "AGR" }, { "id": "RGD:621701", "url": "https://alliancegenome.org/gene/RGD:621701#orthology", "database": "AGR" }, { "id": "FB:FBgn0036260", "url": "https://alliancegenome.org/gene/FB:FBgn0036260#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UHM6-1", "protein_name": "Melanopsin", "gene_name": "OPN4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNPPSGPRVPPSPTQEPSCMATPAPPSWWDSSQSSISSLGRLPSISPTAPGTWAAAWVPLPTVDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRSRSLRTPANMFIINLAVSDFLMSFTQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLATFGVASKRRAAFVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMSFTPAVRAYTMLLCCFVFFLPLLIIIYCYIFIFRAIRETGRALQTFGACKGNGESLWQRQRLQSECKMAKIMLLVILLFVLSWAPYSAVALVAFAGYAHVLTPYMSSVPAVIAKASAIHNPIIYAITHPKYRVAIAQHLPCLGVLLGVSRRHSRPYPSYRSTHRSTLTSHTSNLSWISIRRRQESLGSESEVGWTHMEAAAVWGAAQQANGRSLYGQGLEDLEAKAPPRPQGHEAETPGKTKGLIPSQDPRM", "length": 478 }, "evidence": [ { "id": "HGNC:14449", "url": "https://alliancegenome.org/gene/HGNC:14449#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070111-2", "url": 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"https://www.uniprot.org/uniprotkb/Q9VTU7" } ], "pmid": "" }, { "name": "G protein-coupled photoreceptor activity", "id": "GO:0008020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008020", "evidence": [ { "database": "UniProtKB", "id": "Q9VTU7", "url": "https://www.uniprot.org/uniprotkb/Q9VTU7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VTU7", "url": "https://www.uniprot.org/uniprotkb/Q9VTU7" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VTU7", "url": "https://www.uniprot.org/uniprotkb/Q9VTU7" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "Q9VTU7", "url": "https://www.uniprot.org/uniprotkb/Q9VTU7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "Q9VTU7", "url": "https://www.uniprot.org/uniprotkb/Q9VTU7" } ], "pmid": "" }, { "name": "visual perception", "id": "GO:0007601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007601", "evidence": [ { "database": "UniProtKB", "id": "Q9VTU7", "url": "https://www.uniprot.org/uniprotkb/Q9VTU7" } ], "pmid": "" }, { "name": "G protein-coupled opsin signaling pathway", "id": "GO:0016056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016056", "evidence": [ { "database": "UniProtKB", "id": "Q9VTU7", "url": "https://www.uniprot.org/uniprotkb/Q9VTU7" } ], "pmid": "" }, { "name": "entrainment of circadian clock by photoperiod", "id": "GO:0043153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043153", "evidence": [ { "database": "UniProtKB", "id": "Q9VTU7", "url": "https://www.uniprot.org/uniprotkb/Q9VTU7" } ], "pmid": "" }, { "name": "circadian behavior", "id": "GO:0048512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048512", "evidence": [ { "database": "UniProtKB", "id": "Q9VTU7", "url": "https://www.uniprot.org/uniprotkb/Q9VTU7" } ], "pmid": "" }, { "name": "cellular response to light stimulus", "id": "GO:0071482", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071482", "evidence": [ { "database": "UniProtKB", "id": "Q9VTU7", "url": "https://www.uniprot.org/uniprotkb/Q9VTU7" } ], "pmid": "" }, { "name": "response to photoperiod, blue light", "id": "GO:0009906", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009906", "evidence": [ { "database": "UniProtKB", "id": "Q9VTU7", "url": "https://www.uniprot.org/uniprotkb/Q9VTU7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 11, "end_pos": 13, "annotation": "n_glycosylation_sequon" }, { "start_pos": 35, "end_pos": 37, "annotation": "n_glycosylation_sequon" }, { "start_pos": 471, "end_pos": 473, "annotation": "n_glycosylation_sequon" }, { "start_pos": 70, "end_pos": 72, "annotation": "n_glycosylation_sequon" }, { "start_pos": 79, "end_pos": 81, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VTU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTU7" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 133, "end_pos": 384, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], 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"CG32109-PA", "type": "synonym", "evidence": [ { "id": "NP_729822", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_729822" } ] }, { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "Q9VU04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VU04/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_729822", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_729822" } ] } ], "function": [], "disease": [ { "disease_id": "DOID:0080214", "recommended_name": { "id": "DOID:0080214", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080214", "name": "punctate palmoplantar keratoderma type I", "description": "A punctate palmoplantar keratoderma that is characterized by multiple hyperkeratotic centrally indented papules that develop in early adolescence or later and are irregularly distributed on the palms and soles." 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"Q9VU04-1", "url": "https://www.uniprot.org/uniprotkb/Q9VU04/entry#Q9VU04-1", "sequence": { "sequence": "MDPVVLVLSYGAVPALEIVENILSEVNQSKESTSTECSLNCYKCIIKTKYYNTSINLIPFSGKLEAVPEKILQATEALIIYFDSQDTSFIDTIPKTLAKNEQIQLGFLLTSSTSEEGGLSFGEIKEKTNFLFDIITLRSNVESDPDEAEKDYEEVVEGLKNVVWSNVKFGSDHKEEISADELDSQLKDFENLLLTAQNLRNDTSLTREQFLDRAEQFAGIVSSILNDNDSD", "length": 231, "header": "tr|Q9VU04-1|Q9VU04_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG32109 PE=4 SV=2 CANONICAL=Q9VU04-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VU04", "url": "https://www.uniprot.org/uniprotkb/Q9VU04" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VU04", "url": "https://www.uniprot.org/uniprotkb/Q9VU04" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VU04", "url": "https://www.uniprot.org/uniprotkb/Q9VU04" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VU04", "url": "https://www.uniprot.org/uniprotkb/Q9VU04" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VU04", "url": "https://www.uniprot.org/uniprotkb/Q9VU04" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VU04", "url": "https://www.uniprot.org/uniprotkb/Q9VU04" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VU04", "url": "https://www.uniprot.org/uniprotkb/Q9VU04" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VU04", "url": "https://www.uniprot.org/uniprotkb/Q9VU04" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VU04", "url": "https://www.uniprot.org/uniprotkb/Q9VU04" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VU04", "url": "https://www.uniprot.org/uniprotkb/Q9VU04" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VU04", "url": "https://www.uniprot.org/uniprotkb/Q9VU04" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG32109", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG32109", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q6PD74-1", "protein_name": "Alpha- and gamma-adaptin-binding protein p34", "gene_name": "AAGAB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAGVPCALVTSCSSVFSGDQLVQHILGTEDLIVEVTSNDAVRFYPWTIDNKYYSADINLCVVPNKFLVTAEIAESVQAFVVYFDSTQKSGLDSVSSWLPLAKAWLPEVMILVCDRVSEDGINRQKAQEWCIKHGFELVELSPEELPEEDDDFPESTGVKRIVQALNANVWSNVVMKNDRNQGFSLLNSLTGTNHSIGSADPCHPEQPHLPAADSTESLSDHRGGASNTTDAQVDSIVDPMLDLDIQELASLTTGGGDVENFERLFSKLKEMKDKAATLPHEQRKVHAEKVAKAFWMAIGGDRDEIEGLSSDEEH", "length": 315 }, "evidence": [ { "id": "HGNC:25662", "url": "https://alliancegenome.org/gene/HGNC:25662#orthology", "database": "AGR" }, { "id": "MGI:1914189", "url": "https://alliancegenome.org/gene/MGI:1914189#orthology", "database": "AGR" }, { "id": "RGD:621601", "url": 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{ "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 201, "end_pos": 203 }, { "start_pos": 228, "end_pos": 230 }, { "start_pos": 27, "end_pos": 29 }, { "start_pos": 52, "end_pos": 54 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VU15-1", "uniprot_ac": "Q9VU15", "uniprot_id": "Q9VU15_DROME", "mass": { "chemical_mass": 30272.0, "monoisotopic_mass": 30272.0 }, "refseq": { "ac": "NP_648603", "name": "splicing factor 3a subunit 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648603" }, "gene_names": [ { "name": "Sf3a2", "type": "recommended", "evidence": [ { "id": "Q9VU15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VU15" } ] }, { "name": "CG10754", "type": "synonym", "evidence": [ { "id": "NP_648603", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648603" }, { "id": "Q9VU15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VU15" } ] }, { "name": "CG2807", "type": "synonym", "evidence": [ { "id": "NP_648603", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648603" }, { "id": "Q9VU15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VU15" } ] }, { "name": "Dmel\\CG10754", "type": "synonym", "evidence": [ { "id": "NP_648603", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648603" }, { "id": "Q9VU15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VU15" } ] }, { "name": "Dmel_CG10754", "type": "synonym", "evidence": [ { "id": "Q9VU15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VU15" } ] }, { "name": "SF3A2", "type": "synonym", "evidence": [ { "id": "NP_648603", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648603" }, { "id": "Q9VU15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VU15" } ] }, { "name": "Sf3a2", "type": "synonym", "evidence": [ { "id": "NP_648603", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648603" } ] } ], "protein_names": [ { "name": "Splicing factor 3A subunit 2", "type": "recommended", "evidence": [ { "id": "Q9VU15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VU15/entry#names_and_taxonomy" } ] }, { "name": "CG10754-PA", "type": "synonym", "evidence": [ { "id": "NP_648603", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648603" } ] }, { "name": "Sf3a2-PA", "type": "synonym", "evidence": [ { "id": "NP_648603", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648603" } ] }, { "name": "splicing factor 3a subunit 2", "type": "synonym", "evidence": [ { "id": "NP_648603", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648603" } ] } ], "function": [ { "annotation": "Component of the 17S U2 SnRNP complex of the spliceosome, a large ribonucleoprotein complex that removes introns from transcribed pre-mRNAs. The 17S U2 SnRNP complex (1) directly participates in early spliceosome assembly and (2) mediates recognition of the intron branch site during pre-mRNA splicing by promoting the selection of the pre-mRNA branch-site adenosine, the nucleophile for the first step of splicing. Within the 17S U2 SnRNP complex, SF3A2 is part of the SF3A subcomplex that contributes to the assembly of the 17S U2 snRNP, and the subsequent assembly of the pre-spliceosome 'E' complex and the pre-catalytic spliceosome 'A' complex. Involved in pre-mRNA splicing as a component of pre-catalytic spliceosome 'B' complexes, including the Bact complex. Interacts directly with the duplex formed by U2 snRNA and the intron.", "evidence": [ { "database": "UniProtKB", "id": "Q9VU15", "url": "https://www.uniprot.org/uniprotkb/Q9VU15#function" }, { "database": "UniProtKB", "id": "ARBA00055377", "url": "https://www.uniprot.org/uniprotkb/ARBA00055377#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VU15", "url": "https://www.uniprot.org/uniprotkb/Q9VU15" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Sf3a2", "url": "https://www.uniprot.org/uniprotkb/Q9VU15", "locus": { "chromosome": "3L", "start_pos": 12813028, "end_pos": 12814019, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0036314", "url": "https://www.ensemblgenomes.org/id/FBgn0036314" } ] } } ], "crossref": [ { "id": "FB:FBgn0036314", "url": "https://alliancegenome.org/gene/FB:FBgn0036314", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0036314", "url": "https://bgee.org/?page=gene&gene_id=FBgn0036314", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0036314", "url": "https://flybase.org/reports/FBgn0036314", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "39456", "url": "https://www.ncbi.nlm.nih.gov/gene/39456", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VU15", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VU15*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR000690", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000690", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003604", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003604", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052092", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052092", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG10754", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG10754", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EFWIQIM", "url": "https://omabrowser.org/oma/group/EFWIQIM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VU15", "url": "https://www.orthodb.org/?gene=Q9VU15", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23205", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23205", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23205:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23205:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12874", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12874", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16835", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16835", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q9VU15", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q9VU15", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-DME-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-72163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-9770562", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9770562", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-9943411", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9943411", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_648603", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648603", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VU15", "url": "https://www.uniprot.org/uniprotkb/Q9VU15", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VU15-1", "url": "https://www.uniprot.org/uniprotkb/Q9VU15-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDFQNRAGGKTGSGGVASWSETNRDRKERLRQLALETIDLNKDPYFMKNHLGSYECKLCLTLHNNEGSYLAHTQGKKHQDNLARRAAKEAKEAPSSLLAPEKPRVEPKKFVKIGRPGYRVTKQRELSNGQQSLLFQVDYPEITESIVPRHRFMSAYEQKIEPPDRKWQYLLFAAEPYETIGFKVPSREVEKSEGKFWTHWNRDTKQFFLQFAFKFEPKILPPPPPNLHRALGPPGGFPMPGPPRPAMHPMFNGVHPPPPMLSNN", "length": 264, "header": "tr|Q9VU15-1|Q9VU15_DROME Isoform 1 of Splicing factor 3A subunit 2 OS=Drosophila melanogaster OX=7227 GN=Sf3a2 PE=1 SV=1 CANONICAL=Q9VU15-1" }, "isoforms": [ { "isoform_ac": "Q9VU15-1", "url": "https://www.uniprot.org/uniprotkb/Q9VU15/entry#Q9VU15-1", "sequence": { "sequence": "MDFQNRAGGKTGSGGVASWSETNRDRKERLRQLALETIDLNKDPYFMKNHLGSYECKLCLTLHNNEGSYLAHTQGKKHQDNLARRAAKEAKEAPSSLLAPEKPRVEPKKFVKIGRPGYRVTKQRELSNGQQSLLFQVDYPEITESIVPRHRFMSAYEQKIEPPDRKWQYLLFAAEPYETIGFKVPSREVEKSEGKFWTHWNRDTKQFFLQFAFKFEPKILPPPPPNLHRALGPPGGFPMPGPPRPAMHPMFNGVHPPPPMLSNN", "length": 264, "header": "tr|Q9VU15-1|Q9VU15_DROME Isoform 1 of Splicing factor 3A subunit 2 OS=Drosophila melanogaster OX=7227 GN=Sf3a2 PE=1 SV=1 CANONICAL=Q9VU15-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VU15", "url": "https://www.uniprot.org/uniprotkb/Q9VU15" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VU15", "url": "https://www.uniprot.org/uniprotkb/Q9VU15" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VU15", "url": "https://www.uniprot.org/uniprotkb/Q9VU15" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VU15", "url": "https://www.uniprot.org/uniprotkb/Q9VU15" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VU15", "url": "https://www.uniprot.org/uniprotkb/Q9VU15" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VU15", "url": "https://www.uniprot.org/uniprotkb/Q9VU15" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VU15", "url": "https://www.uniprot.org/uniprotkb/Q9VU15" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VU15", "url": "https://www.uniprot.org/uniprotkb/Q9VU15" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VU15", "url": "https://www.uniprot.org/uniprotkb/Q9VU15" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VU15", "url": "https://www.uniprot.org/uniprotkb/Q9VU15" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VU15", "url": "https://www.uniprot.org/uniprotkb/Q9VU15" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], 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"https://www.uniprot.org/uniprotkb/Q9VU37" } ] }, { "name": "Dmel\\Ste14", "type": "synonym", "evidence": [ { "id": "NP_001261793", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261793" }, { "id": "Q9VU37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VU37" } ] }, { "name": "Dmel_CG11268", "type": "synonym", "evidence": [ { "id": "Q9VU37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VU37" } ] }, { "name": "ICMT", "type": "synonym", "evidence": [ { "id": "NP_001261793", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261793" }, { "id": "Q9VU37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VU37" } ] }, { "name": "Icmt", "type": "synonym", "evidence": [ { "id": "NP_001261793", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261793" } ] }, { "name": "Ste14", "type": "synonym", "evidence": [ { "id": "NP_001261793", "database": "RefSeq", 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"https://www.ncbi.nlm.nih.gov/protein/NP_001261793" } ] }, { "name": "Icmt-PB", "type": "synonym", "evidence": [ { "id": "NP_001261793", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261793" } ] }, { "name": "isoprenylcysteine carboxyl methyltransferase, isoform B", "type": "synonym", "evidence": [ { "id": "NP_001261793", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261793" } ] }, { "name": "isoprenylcysteine carboxylmethyltransferase", "type": "synonym", "evidence": [ { "id": "NP_001261793", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261793" } ] } ], "function": [ { "annotation": "Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues.", "evidence": [ { "database": "UniProtKB", "id": "Q9VU37", "url": "https://www.uniprot.org/uniprotkb/Q9VU37#function" }, { "database": "UniProtKB", "id": "ARBA00023572", "url": "https://www.uniprot.org/uniprotkb/ARBA00023572#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VU37", "url": "https://www.uniprot.org/uniprotkb/Q9VU37" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Icmt", "url": "https://www.uniprot.org/uniprotkb/Q9VU37", "locus": {} } ], "crossref": [ { "id": "FB:FBgn0036336", "url": "https://alliancegenome.org/gene/FB:FBgn0036336", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0036336", "url": "https://bgee.org/?page=gene&gene_id=FBgn0036336", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0036336", "url": "https://flybase.org/reports/FBgn0036336", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "39478", "url": "https://www.ncbi.nlm.nih.gov/gene/39478", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VU37", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VU37*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR007269", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007269", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG11268", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG11268", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GMVPQVW", "url": "https://omabrowser.org/oma/group/GMVPQVW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VU37", "url": "https://www.orthodb.org/?gene=Q9VU37", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12714", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12714", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12714:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12714:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04140", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04140", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-163841", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-163841", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-9648002", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9648002", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001261793", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261793", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "21672", "url": "https://www.rhea-db.org/rhea/21672", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q9VU37", "url": "https://www.uniprot.org/uniprotkb/Q9VU37", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VU37-1", "url": "https://www.uniprot.org/uniprotkb/Q9VU37-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCAKSRVASPGAGGTSLCSEGRISLYCFLITAALVLIPSVPQNLYGVVPQVWGAVLWGPFLYYALINMIIRFVLRNHDYQVAIRASFLGFAMAVSVLVICFAPTEWQQFGAYGCFMSLFHYSEFLVIAFANPRTLSLDSFMLNHSVHYGLAAAASWIEFSLEVYYLPQFKRYGYIWVAGVVLCLLGEMVRKAAIITAGRSFTHLVQNEKHSEHKLITSGIYAYCRHPSYVGWFWWSIGTQIVLLNPICICIYTLVSWLFFHDRIYVEEYSLLNFFQSDYVRYQKRVPTGLPFIRGYLVD", "length": 299, "header": "tr|Q9VU37-1|Q9VU37_DROME Isoform 1 of Protein-S-isoprenylcysteine O-methyltransferase OS=Drosophila melanogaster OX=7227 GN=Icmt PE=3 SV=1 CANONICAL=Q9VU37-1" }, "isoforms": [ { "isoform_ac": "Q9VU37-1", "url": "https://www.uniprot.org/uniprotkb/Q9VU37/entry#Q9VU37-1", "sequence": { "sequence": "MCAKSRVASPGAGGTSLCSEGRISLYCFLITAALVLIPSVPQNLYGVVPQVWGAVLWGPFLYYALINMIIRFVLRNHDYQVAIRASFLGFAMAVSVLVICFAPTEWQQFGAYGCFMSLFHYSEFLVIAFANPRTLSLDSFMLNHSVHYGLAAAASWIEFSLEVYYLPQFKRYGYIWVAGVVLCLLGEMVRKAAIITAGRSFTHLVQNEKHSEHKLITSGIYAYCRHPSYVGWFWWSIGTQIVLLNPICICIYTLVSWLFFHDRIYVEEYSLLNFFQSDYVRYQKRVPTGLPFIRGYLVD", "length": 299, "header": "tr|Q9VU37-1|Q9VU37_DROME Isoform 1 of Protein-S-isoprenylcysteine O-methyltransferase OS=Drosophila melanogaster OX=7227 GN=Icmt PE=3 SV=1 CANONICAL=Q9VU37-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VU37", "url": "https://www.uniprot.org/uniprotkb/Q9VU37" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VU37", "url": "https://www.uniprot.org/uniprotkb/Q9VU37" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VU37", "url": "https://www.uniprot.org/uniprotkb/Q9VU37" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VU37", "url": "https://www.uniprot.org/uniprotkb/Q9VU37" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VU37", "url": "https://www.uniprot.org/uniprotkb/Q9VU37" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VU37", "url": "https://www.uniprot.org/uniprotkb/Q9VU37" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VU37", "url": "https://www.uniprot.org/uniprotkb/Q9VU37" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VU37", "url": "https://www.uniprot.org/uniprotkb/Q9VU37" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VU37", "url": "https://www.uniprot.org/uniprotkb/Q9VU37" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VU37", "url": "https://www.uniprot.org/uniprotkb/Q9VU37" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VU37", "url": "https://www.uniprot.org/uniprotkb/Q9VU37" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], 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"MAGCAARAPPGSEARLSLATFLLGASVLALPLLTRAGLQGRTGLALYVAGLNALLLLLYRPPRYQIAIRACFLGFVFGCGTLLSFSQSSWSHFGWYMCSLSLFHYSEYLVTAVNNPKSLSLDSFLLNHSLEYTVAALSSWLEFTLENIFWPELKQITWLSVTGLLMVVFGECLRKAAMFTAGSNFNHVVQNEKSDTHTLVTSGVYAWFRHPSYVGWFYWSIGTQVMLCNPICGVSYALTVWRFFRDRTEEEEISLIHFFGEEYLEYKKRVPTGLPFIKGVKVDL", "length": 284 }, "evidence": [ { "id": "RGD:621618", "url": "https://alliancegenome.org/gene/RGD:621618#orthology", "database": "AGR" }, { "id": "MGI:1888594", "url": "https://alliancegenome.org/gene/MGI:1888594#orthology", "database": "AGR" }, { "id": "HGNC:5350", "url": "https://alliancegenome.org/gene/HGNC:5350#orthology", "database": "AGR" }, { "id": "FB:FBgn0036336", "url": "https://alliancegenome.org/gene/FB:FBgn0036336#orthology", "database": "AGR" }, { "id": "SGD:S000002818", "url": "https://alliancegenome.org/gene/SGD:S000002818#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P32584-1", "protein_name": "Protein-S-isoprenylcysteine O-methyltransferase", "gene_name": "STE14", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MHQDFQEDEHEYPDIRRNPLHEVTMTSYILGILLGIFVGLFPQIRFKNFNLFIIALSLFHFLEYYITAKYNPLKVHSESFLLNNGKSYMAAHSFAILECLVESFLFPDLKIFSYSLATKLCTVLGCLLVILGQYTRTIAMHTAGHSFSHIVKTKKESDHVLVKTGVYSWSRHPSYLGFFWWAIGTQLLLLNPLSLVIFIFVLWKFFSDRIRVEEKYLIEFFSAEYIEYKNKVGVGIPFI", "length": 239 }, "evidence": [ { "id": "RGD:621618", "url": "https://alliancegenome.org/gene/RGD:621618#orthology", "database": "AGR" }, { "id": "MGI:1888594", "url": "https://alliancegenome.org/gene/MGI:1888594#orthology", "database": "AGR" }, { "id": "HGNC:5350", "url": "https://alliancegenome.org/gene/HGNC:5350#orthology", "database": "AGR" }, { "id": "FB:FBgn0036336", "url": "https://alliancegenome.org/gene/FB:FBgn0036336#orthology", "database": "AGR" }, { "id": "SGD:S000002818", "url": "https://alliancegenome.org/gene/SGD:S000002818#orthology", "database": "AGR" }, { "id": "Q9VU37", "url": "https://omabrowser.org/oma/group/Q9VU37/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q9EQK7-1", "protein_name": "Protein-S-isoprenylcysteine O-methyltransferase", "gene_name": "Icmt", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAARRGSAGSEARLSLATFLLGASVLALPLLTRAGLQGRTGLALYVAGLNALLLLLYRPPRYQIAIRACFLGFVFGCGVLLSFSQSSWNHFGWYVCSLSLFHYSEYLVTAVNNPKSLSLDSFLLNHSLEYTVAALSSWIEFTLENIFWPELKQITWLSATGLLMVVFGECLRKAAMFTAGSNFNHVVQSEKSDTHTLVTSGVYAWCRHPSYVGWFYWSIGTQVMLCNPICGVVYALTVWRFFRDRTEEEEISLIHFFGEEYLDYKKRVPTGLPFIKGVKVEL", "length": 283 }, "evidence": [ { "id": "RGD:621618", "url": "https://alliancegenome.org/gene/RGD:621618#orthology", "database": "AGR" }, { "id": "MGI:1888594", "url": "https://alliancegenome.org/gene/MGI:1888594#orthology", "database": "AGR" }, { "id": "HGNC:5350", "url": "https://alliancegenome.org/gene/HGNC:5350#orthology", "database": "AGR" }, { "id": "FB:FBgn0036336", "url": "https://alliancegenome.org/gene/FB:FBgn0036336#orthology", "database": "AGR" }, { "id": "SGD:S000002818", "url": "https://alliancegenome.org/gene/SGD:S000002818#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9FMW9-1", "protein_name": "Protein-S-isoprenylcysteine O-methyltransferase A", "gene_name": "ICMTA", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MTEIFSDTSIRQLSQMLLSLIFFHISEYILAITIHGASNVTLSSLLITKHYALAMLLSLLEYLTEIILFPGLKQHWWVSNFGLIMIIVGEIIRKAAIITAGRSFTHLIKINYEEHHGLVTHGVYRLMRHPSYCGFLIWSVGTQVMLCNPVSAVAFAVVVWRFFAQRIPYEEYFLNQFFGVQYLEYAESVASGVPFVN", "length": 197 }, "evidence": [ { "id": "Q9VU37", "url": "https://omabrowser.org/oma/group/Q9VU37/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9WVM4-1", "protein_name": "Protein-S-isoprenylcysteine O-methyltransferase", "gene_name": "Icmt", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGCAARVPPGSEARLSLATFLLGASVLALPLLTRAGLQGRTGLALYVAGLNALLLLLYRPPRYQIAIRACFLGFVFGCGVLLSFSQSSWNHFGWYVCSLSLFHYSEYLVTAVNNPKSLSLDSFLLNHSLEYTVAALSSWIEFTLENIFWPELKQITWLSAAGLLMVIFGECLRKVAMFTAGSNFNHVVQSEKSDTHTLVTSGVYAWCRHPSYVGWFYWSIGTQVMLCNPICGVVYALTVWRFFRDRTEEEEISLIHFFGEEYLDYKKRVPTGLPFIKGVKVGL", "length": 284 }, "evidence": [ { "id": "RGD:621618", "url": "https://alliancegenome.org/gene/RGD:621618#orthology", "database": "AGR" }, { "id": "MGI:1888594", "url": "https://alliancegenome.org/gene/MGI:1888594#orthology", "database": "AGR" }, { "id": "HGNC:5350", "url": "https://alliancegenome.org/gene/HGNC:5350#orthology", "database": "AGR" }, { "id": "FB:FBgn0036336", "url": "https://alliancegenome.org/gene/FB:FBgn0036336#orthology", "database": "AGR" }, { "id": "SGD:S000002818", "url": "https://alliancegenome.org/gene/SGD:S000002818#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q9VU37", "url": "https://www.uniprot.org/uniprotkb/Q9VU37" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VU37", "url": "https://www.uniprot.org/uniprotkb/Q9VU37" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "Q9VU37", "url": "https://www.uniprot.org/uniprotkb/Q9VU37" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity", "id": "GO:0004671", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004671", "evidence": [ { "database": "UniProtKB", "id": "Q9VU37", "url": "https://www.uniprot.org/uniprotkb/Q9VU37" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 143, "end_pos": 145, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "21672", "name": "", "equation": "[protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine + S-adenosyl-L-methionine = [protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine methyl ester + S-adenosyl-L-homocysteine", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VU37-1" ], "evidence": [ { "id": "21672", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/21672" } ] }, { "id": "R-DME-6788650", "name": "ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [ "R-ALL-6788753" ], "output_participant_list": [ "R-ALL-6788758" ], "enzyme_list": [ "Q9VU37-1" ], "evidence": [ { "id": "R-DME-6788650", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6788650" } ] }, { "id": "R-DME-9647977", "name": "ICMT methylates S-Farn RAS proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P08646-1", "Q9VU37-1" ], "evidence": [ { "id": "R-DME-9647977", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9647977" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-6788753", "participant_name": "S-FARN-Cys [cytosol]", "crossref": [ { "id": "86019", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-6788758", "participant_name": "S-FARN-CME [cytosol]", "crossref": [ { "id": "ZINC000031259909", "database": "ZINC", "url": "" }, { "id": "87167", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "P08646", "gene_name": "Ras85D", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "P08646", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08646" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "P08646", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08646" } ] } ] }, { "uniprot_ac": "Q9VU37", "gene_name": "Icmt", "activity": [ { "ec_number": "2.1.1.100", "activity": "[protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine + S-adenosyl-L-methionine = [protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine methyl ester + S-adenosyl-L-homocysteine.", "evidence": [ { "id": "Q9VU37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VU37" } ] }, { "ec_number": "2.1.1.100", "activity": "", "evidence": [ { "id": "Q9VU37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VU37" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.1.1.100", "ec_name": "[protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine + S-adenosyl-L-methionine = [protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine methyl ester + S-adenosyl-L-homocysteine.", "evidence": [ { "id": "2.1.1.100", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.100" }, { "id": "2.1.1.100", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.1.1.100" } ] } ], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 143, "end_pos": 145 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"CG11274-PA", "type": "synonym", "evidence": [ { "id": "NP_648627", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648627" } ] }, { "name": "SRm160", "type": "synonym", "evidence": [ { "id": "NP_648627", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648627" } ] }, { "name": "Serine-arginine repetitive matrix 1", "type": "synonym", "evidence": [ { "id": "NP_648627", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648627" } ] }, { "name": "Srrm1-PA", "type": "synonym", "evidence": [ { "id": "NP_648627", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648627" } ] } ], "function": [], "disease": [ { "disease_id": "DOID:11714", "recommended_name": { "id": "DOID:11714", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11714", "name": "gestational diabetes", "description": "A diabetes mellitus that manifests during pregnancy." }, "synonyms": [ { "id": "DOID:11714", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11714", "name": "GDM", "description": "" }, { "id": "DOID:11714", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11714", "name": "Gestational diabetes mellitus", "description": "" }, { "id": "DOID:11714", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11714", "name": "Maternal gestational diabetes mellitus", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "11714", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11714" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VU43", "url": "https://www.uniprot.org/uniprotkb/Q9VU43" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Srrm1", "url": "https://www.uniprot.org/uniprotkb/Q9VU43", "locus": { "chromosome": "3L", "start_pos": 13040976, "end_pos": 13036821, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0036340", "url": "https://www.ensemblgenomes.org/id/FBgn0036340" } ] } } ], "crossref": [ { "id": "FB:FBgn0036340", "url": "https://alliancegenome.org/gene/FB:FBgn0036340", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0036340", "url": "https://bgee.org/?page=gene&gene_id=FBgn0036340", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0036340", "url": "https://flybase.org/reports/FBgn0036340", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "39483", "url": "https://www.ncbi.nlm.nih.gov/gene/39483", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VU43", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VU43*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR002483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG11274", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG11274", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DHRQSPM", "url": "https://omabrowser.org/oma/group/DHRQSPM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VU43", "url": "https://www.orthodb.org/?gene=Q9VU43", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23148", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23148", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23148:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23148:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01480", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01480", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-159236", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-159236", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-72163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-9013418", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9013418", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-9013422", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9013422", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_648627", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648627", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VU43", "url": "https://www.uniprot.org/uniprotkb/Q9VU43", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VU43-1", "url": "https://www.uniprot.org/uniprotkb/Q9VU43-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMFTGTNQQQDTRFSDKEKKLMKQMKFGDCLNKRVDMSKVKLDVLRPWISKKITDILHIEDDVVVEFVYNQLEEEKYPCPKKMQINMTGFLNGRNARQFMGELWALLLSAQESDSGIPAEFIQQKKDEILKREEEQRQRDRSRSRSRSRSQRDSSRRDRQRDRSKSKSRSRSRSMKPANNNGSVPSAAREAAANAAAKIRKRGSSSAARPGSRERRSSRRPRSRSRSRSRTAGKKTGSVEPAPAKTVNGRHSTDKSSPVPPASKNKSRSRSHSRSRSPRSRSRSPSAKRSRSRSSSRRSRRRGRSSSISLSPERNQDQFEHRRNKNSVQNKRQYRNNRGDSASSMERGNDRGRQFGGGGGGRRGGRRFSPRGRSPMRQDNGGGNGGNRFQRSNSRRRSRSRRLSRSPMRYSRSPRRFNNRRRSPMMNFRGGGRGGGRGGGHRQMWQHRGGSPNFRGGGRIHWQARHSPGGGGRGGGGGMGRFDRRQSPQQNRYNRDHRQSPMQQNQPFRKQFSPHQGPGRRFSSPQQRRNSRDRRPNSRERRSSPGGGGGHMNRWDNPPPARNRRSSSGSSAGGRQQRQRSASPPEKRRSSHSRSRSLSRNRSRSRSSSQHSRKRESPIGRSSVEYAGPAVNTIDLCREEQQRKNKPETIIVLDEGPAVRSSYASLSRTPSPFLKPHERLAAAKAAAAASAAVPKKSRDQSQSSSSDSSAESDDSEEQPRRKKQPTNMETSKGKKEKVRRSSESSTSSEQSDDEDNSSGDERLKKKLQQRKSKEAAALKGKEKEHEKEKDKRRSDKKSKRGAISSGDEESTSSRKRGHKKTRRDEAGDNSDSEDEHVPKKKRKKAKKPADSSDSDSEASSKRKKHKKHKKHSKKSKKHKKHKRKCSAGKSRADSSSQGSSDEDEQLPHSVAAKRNGNAGKLALLLPGASGAGVINEDLEKQLRERALKSMKKLD", "length": 954, "header": "tr|Q9VU43-1|Q9VU43_DROME Isoform 1 of Serine/arginine repetitive matrix protein 1 OS=Drosophila melanogaster OX=7227 GN=Srrm1 PE=1 SV=1 CANONICAL=Q9VU43-1" }, "isoforms": [ { "isoform_ac": "Q9VU43-1", "url": "https://www.uniprot.org/uniprotkb/Q9VU43/entry#Q9VU43-1", "sequence": { "sequence": "MMFTGTNQQQDTRFSDKEKKLMKQMKFGDCLNKRVDMSKVKLDVLRPWISKKITDILHIEDDVVVEFVYNQLEEEKYPCPKKMQINMTGFLNGRNARQFMGELWALLLSAQESDSGIPAEFIQQKKDEILKREEEQRQRDRSRSRSRSRSQRDSSRRDRQRDRSKSKSRSRSRSMKPANNNGSVPSAAREAAANAAAKIRKRGSSSAARPGSRERRSSRRPRSRSRSRSRTAGKKTGSVEPAPAKTVNGRHSTDKSSPVPPASKNKSRSRSHSRSRSPRSRSRSPSAKRSRSRSSSRRSRRRGRSSSISLSPERNQDQFEHRRNKNSVQNKRQYRNNRGDSASSMERGNDRGRQFGGGGGGRRGGRRFSPRGRSPMRQDNGGGNGGNRFQRSNSRRRSRSRRLSRSPMRYSRSPRRFNNRRRSPMMNFRGGGRGGGRGGGHRQMWQHRGGSPNFRGGGRIHWQARHSPGGGGRGGGGGMGRFDRRQSPQQNRYNRDHRQSPMQQNQPFRKQFSPHQGPGRRFSSPQQRRNSRDRRPNSRERRSSPGGGGGHMNRWDNPPPARNRRSSSGSSAGGRQQRQRSASPPEKRRSSHSRSRSLSRNRSRSRSSSQHSRKRESPIGRSSVEYAGPAVNTIDLCREEQQRKNKPETIIVLDEGPAVRSSYASLSRTPSPFLKPHERLAAAKAAAAASAAVPKKSRDQSQSSSSDSSAESDDSEEQPRRKKQPTNMETSKGKKEKVRRSSESSTSSEQSDDEDNSSGDERLKKKLQQRKSKEAAALKGKEKEHEKEKDKRRSDKKSKRGAISSGDEESTSSRKRGHKKTRRDEAGDNSDSEDEHVPKKKRKKAKKPADSSDSDSEASSKRKKHKKHKKHSKKSKKHKKHKRKCSAGKSRADSSSQGSSDEDEQLPHSVAAKRNGNAGKLALLLPGASGAGVINEDLEKQLRERALKSMKKLD", "length": 954, "header": "tr|Q9VU43-1|Q9VU43_DROME Isoform 1 of Serine/arginine repetitive matrix protein 1 OS=Drosophila melanogaster OX=7227 GN=Srrm1 PE=1 SV=1 CANONICAL=Q9VU43-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VU43", "url": "https://www.uniprot.org/uniprotkb/Q9VU43" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VU43", "url": "https://www.uniprot.org/uniprotkb/Q9VU43" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VU43", "url": "https://www.uniprot.org/uniprotkb/Q9VU43" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VU43", "url": "https://www.uniprot.org/uniprotkb/Q9VU43" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VU43", "url": "https://www.uniprot.org/uniprotkb/Q9VU43" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VU43", "url": "https://www.uniprot.org/uniprotkb/Q9VU43" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VU43", "url": "https://www.uniprot.org/uniprotkb/Q9VU43" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VU43", "url": "https://www.uniprot.org/uniprotkb/Q9VU43" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VU43", "url": "https://www.uniprot.org/uniprotkb/Q9VU43" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VU43", "url": "https://www.uniprot.org/uniprotkb/Q9VU43" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VU43", "url": "https://www.uniprot.org/uniprotkb/Q9VU43" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG11274", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG11274", "resource": "KEGG Pathway" }, { "id": "R-DME-159236", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-159236", "resource": "Reactome", "description": "Transport of Mature mRNA derived from an Intron-Containing Transcript" }, { "id": "R-DME-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" }, { "id": "R-DME-9013418", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9013418", "resource": "Reactome", "description": "RHOBTB2 GTPase cycle" }, { "id": "R-DME-9013422", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9013422", "resource": "Reactome", "description": "RHOBTB1 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "E7F1X7-1", "protein_name": "Serine/arginine repetitive matrix protein 1", "gene_name": "srrm1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDAGFFRGTSAEQDNRFSNKHKKLLKQLKFAECLEKKVDMTKVNLEVIKPWITQRVTEILGFEDDVVIEFVFNQLEEKNPDGKMMQINLTGFLNGKNAREFMKDLWPLLLSAQENIAGIPSAFLEQKKEEIKQRQIEQEKLASLKKVDEDKREKENKERAQSKSPKRRKSRSPVKRDRKSSPSRSRSPRRKISPAASPPSSPPNHKEEPKREPDQSESSKPEPLIQEASSTSDLVTEMKPDSVSEPVKESSPDKTSKSEDRPKPRDREKDGRKDRPRHRSRSRSPRSRRRPRSRSRSFSPRRRTSPRRRISPRRRSPPRRQPPSRHRRSRSPVRRRRSRSRSSSGSSSSRSPHKRAGKRGSATPPRKLARRTDLSSPPRRRGRSPSGPDTSPSAGKHRPGGRNDSRSPSPKPRRSDASDSEEDKLGKGSTADSVQQRRQYRRQNQQSSSDTGSSSSSEDEGPRRQNRGAGARNGEIRRRRSHSPASPRRRHRDASPRKRRSPSPPGRRHRSQSPVRRRRSPSPPPRRRSPSPPPRRFTPPIQRRYSPPSPSPAQKRRSSGSPPKRRRSPSPMPKRRIPPSPPPKRRMSPSPPPKRRKSPSPMSKRRTSPSVSKRRTSPSPVAKHRRSPSPMSKRRTCASPVSKRRNSPSPAPQRRSSPSPMPKHRGSPSPVTKRHTSRSPKRSRGTSPGKRRTPPSSASPPPRHRRNSPNPPAAQRGRDTRSSPPAHTTRVSSSPPGRYGASGSSPQRQRRQTSPSHSTRPIRRVSRTPEPRKSQRGSQSPPPERRQVSRSPSASPPPAQKRPASVSPSRSTSRSPPPPAKKNSSVSPSPSPNKNSDAEGGKKKKKKKEKKHKKDKKHKKHKKQKKEKGGEEKSGGATGGHGPEAEPDSDQKKESESEVEDSLDDLEKHLREKALRSMRKAQMSPSSQS", "length": 929 }, "evidence": [ { "id": "HGNC:16638", "url": "https://alliancegenome.org/gene/HGNC:16638#orthology", "database": "AGR" }, { "id": "MGI:1858303", "url": "https://alliancegenome.org/gene/MGI:1858303#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F7FND9-1", "protein_name": "Serine/arginine repetitive matrix protein 1", "gene_name": "Srrm1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDAGFFRGTSAEQDNRFSNKQKKLLKQLKFAECLEKKVDMSKVNLEVIKPWITKRVTEILGFEDDVVIEFIFNQLEVKNPDSKMMQINLTGFLNGKNAREFMGELWPLLLSAQENIAGIPSAFLELKKEEIKQRQIEQEKLASLKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKSPELPEPSVRMKDSSVQEATSTSDILKAPKPEPVPEPKEPSPEKNSKKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPGRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSSPATPPPKTRHSPTPQQSNRARKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGSKMAAADSVQQRRQYRRQNQQSSSDSGSSSTSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRMQMGKRWQSPVTKSSRRRRSPSPPPARRRRSPSPAPPPPPPPPPRRRRSPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSPPVTKRRSPSLSSKHRKGSSPGRSTREARSPQPNKRHSPSPRPRAPQTSSPPPVRRGASASPQGRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPTAKKPPAPPSPVQSQSPSTNWSPAAPAKKAKSPTPSPSPARNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAVATPAPAAPAAVSAAATPSAQEEPAAAPEPRKETESEAEDDNLDDLERHLREKALRSMRKAQVSPQS", "length": 922 }, "evidence": [ { "id": "HGNC:16638", "url": "https://alliancegenome.org/gene/HGNC:16638#orthology", "database": "AGR" }, { "id": "MGI:1858303", "url": "https://alliancegenome.org/gene/MGI:1858303#orthology", "database": "AGR" }, { "id": "RGD:1311258", "url": "https://alliancegenome.org/gene/RGD:1311258#orthology", "database": "AGR" }, { "id": "FB:FBgn0036340", "url": "https://alliancegenome.org/gene/FB:FBgn0036340#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q52KI8-1", "protein_name": "Serine/arginine repetitive matrix protein 1", "gene_name": "Srrm1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDAGFFRGTSAEQDNRFSNKQKKLLKQLKFAECLEKKVDMSKVNLEVIKPWITKRVTEILGFEDDVVIEFIFNQLEVKNPDSKMMQINLTGFLNGKNAREFMGELWPLLLSAQENIAGIPSAFLELKKEEIKQRQIEQEKLASLKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKSPELPEPSVRMKDSSVQEATSTSDILKAPKPEPVPEPKEPSPEKNSKKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPGRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSSPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGSKMAAADSVQQRRQYRRQNQQSSSDSGSSSTSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRMQMGKRWQSPVTKSSRRRRSPSPPPARRRRSPSPAPPPPPPPPPPRRRRSPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSPTVTKRRSPSLSSKHRKGSSPGRSTREARSPQPNKRHSPSPRPRAPQTSSPPPVRRGASASPQGRQSPSPSTRPIRRVSRTPEPKKIKKTAMATQRNIRRVSKSPKADSLSRAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPAKKAKSPTPSLSPARNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVTIATPATAAPAAVSAATTTSAQEEPAAAPEPRKETESEAEDDNLDDLERHLREKALRSMRKAQVSPQS", "length": 946 }, "evidence": [ { "id": 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"MDAGFFRGTSAEQDNRFSNKQKKLLKQLKFAECLEKKVDMSKVNLEVIKPWITKRVTEILGFEDDVVIEFIFNQLEVKNPDSKMMQINLTGFLNGKNAREFMGELWPLLLSAQENIAGIPSAFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQEEPVAAPEPKKETESEAEDNLDDLEKHLREKALRSMRKAQVSPQS", "length": 904 }, "evidence": [ { "id": "HGNC:16638", "url": 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"Q9VU43", "url": "https://www.uniprot.org/uniprotkb/Q9VU43" } ], "pmid": "" }, { "name": "regulation of alternative mRNA splicing, via spliceosome", "id": "GO:0000381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000381", "evidence": [ { "database": "UniProtKB", "id": "Q9VU43", "url": "https://www.uniprot.org/uniprotkb/Q9VU43" } ], "pmid": "" }, { "name": "somatic sex determination", "id": "GO:0018993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018993", "evidence": [ { "database": "UniProtKB", "id": "Q9VU43", "url": "https://www.uniprot.org/uniprotkb/Q9VU43" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q9VU43", "url": "https://www.uniprot.org/uniprotkb/Q9VU43" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VU43", "url": "https://www.uniprot.org/uniprotkb/Q9VU43" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "Q9VU43", "url": "https://www.uniprot.org/uniprotkb/Q9VU43" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "Q9VU43", "url": "https://www.uniprot.org/uniprotkb/Q9VU43" } ], "pmid": "" }, { "name": "precatalytic spliceosome", "id": "GO:0071011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071011", "evidence": [ { "database": "UniProtKB", "id": "Q9VU43", "url": "https://www.uniprot.org/uniprotkb/Q9VU43" } ], "pmid": "" }, { "name": "exon-exon junction complex", "id": "GO:0035145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035145", "evidence": [ { "database": "UniProtKB", "id": "Q9VU43", "url": "https://www.uniprot.org/uniprotkb/Q9VU43" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 181, "end_pos": 183, "annotation": "n_glycosylation_sequon" }, { "start_pos": 265, "end_pos": 267, "annotation": "n_glycosylation_sequon" }, { "start_pos": 601, "end_pos": 603, "annotation": "n_glycosylation_sequon" }, { "start_pos": 756, "end_pos": 758, "annotation": "n_glycosylation_sequon" }, { "start_pos": 86, "end_pos": 88, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VU43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VU43" }, { "id": "PS51025", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51025" } 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"database": "UniProtKB", "id": "Q9VU46", "url": "https://www.uniprot.org/uniprotkb/Q9VU46" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG11279", "url": "https://www.uniprot.org/uniprotkb/Q9VU46", "locus": { "chromosome": "3L", "start_pos": 13048919, "end_pos": 13046977, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0036342", "url": "https://www.ensemblgenomes.org/id/FBgn0036342" } ] } } ], "crossref": [ { "id": "FB:FBgn0036342", "url": "https://alliancegenome.org/gene/FB:FBgn0036342", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0036342", "url": "https://bgee.org/?page=gene&gene_id=FBgn0036342", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0036342", "url": "https://flybase.org/reports/FBgn0036342", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "39486", "url": "https://www.ncbi.nlm.nih.gov/gene/39486", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VU46", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VU46*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR019034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG11279", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG11279", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KHHSTQA", "url": "https://omabrowser.org/oma/group/KHHSTQA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PF09495", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09495", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001261795", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261795", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VU46", 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"phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VU46", "url": "https://www.uniprot.org/uniprotkb/Q9VU46" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VU46", "url": "https://www.uniprot.org/uniprotkb/Q9VU46" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VU46", "url": "https://www.uniprot.org/uniprotkb/Q9VU46" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VU46", "url": "https://www.uniprot.org/uniprotkb/Q9VU46" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VU46", "url": "https://www.uniprot.org/uniprotkb/Q9VU46" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VU46", "url": "https://www.uniprot.org/uniprotkb/Q9VU46" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VU46", "url": "https://www.uniprot.org/uniprotkb/Q9VU46" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VU46", "url": "https://www.uniprot.org/uniprotkb/Q9VU46" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VU46", "url": "https://www.uniprot.org/uniprotkb/Q9VU46" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VU46", "url": "https://www.uniprot.org/uniprotkb/Q9VU46" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VU46", "url": "https://www.uniprot.org/uniprotkb/Q9VU46" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], 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"authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VU49-1", "uniprot_ac": "Q9VU49", "uniprot_id": "Q9VU49_DROME", "mass": { "chemical_mass": 16287.0, "monoisotopic_mass": 16287.0 }, "refseq": { "ac": "NP_648631", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648631" }, "gene_names": [ { "name": "Dmel\\CG17300", "type": "recommended", "evidence": [ { "id": "Q9VU49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VU49" } ] }, { "name": "CG17300", "type": "synonym", "evidence": [ { "id": "NP_648631", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648631" }, { "id": "Q9VU49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VU49" } ] }, { "name": "Dmel\\CG17300", "type": "synonym", "evidence": [ { "id": "NP_648631", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648631" } ] }, { "name": "Dmel_CG17300", "type": "synonym", "evidence": [ { "id": "Q9VU49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VU49" } ] } ], "protein_names": [ { "name": "ATP synthase subunit b", "type": "recommended", "evidence": [ { "id": "Q9VU49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VU49/entry#names_and_taxonomy" } ] }, { "name": "CG17300-PA", "type": "synonym", "evidence": [ { "id": "NP_648631", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648631" } ] }, { "name": "testis-enriched subunit b", "type": "synonym", "evidence": [ { "id": "NP_648631", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648631" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_648631", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648631" } ] } ], "function": [ { "annotation": "Subunit b, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro. Part of the complex F(0) domain. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.", "evidence": [ { "database": "UniProtKB", "id": "Q9VU49", "url": "https://www.uniprot.org/uniprotkb/Q9VU49#function" }, { "database": "UniProtKB", "id": "RU368017", "url": "https://www.uniprot.org/uniprotkb/RU368017#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VU49", "url": "https://www.uniprot.org/uniprotkb/Q9VU49" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG17300", "url": "https://www.uniprot.org/uniprotkb/Q9VU49", "locus": { "chromosome": "3L", "start_pos": 13086387, "end_pos": 13087289, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0036345", "url": "https://www.ensemblgenomes.org/id/FBgn0036345" } ] } } ], "crossref": [ { "id": "FB:FBgn0036345", "url": "https://alliancegenome.org/gene/FB:FBgn0036345", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0036345", "url": "https://bgee.org/?page=gene&gene_id=FBgn0036345", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0036345", "url": "https://flybase.org/reports/FBgn0036345", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "39489", "url": "https://www.ncbi.nlm.nih.gov/gene/39489", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013837", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013837", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG17300", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG17300", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KHEHSGL", "url": "https://omabrowser.org/oma/group/KHEHSGL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VU49", "url": "https://www.orthodb.org/?gene=Q9VU49", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12733", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12733", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12733:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12733:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "NP_648631", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648631", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VU49", "url": "https://www.uniprot.org/uniprotkb/Q9VU49", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VU49-1", "url": "https://www.uniprot.org/uniprotkb/Q9VU49-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFSRLALRPLTVATSRSATTHSAQGLSRLPGHGSPGKVRPGFPSDNWVKGPMGVGLLAYICSGDCCAIKHEHSGLSLGIMEDGYYSSGITIGILTTFAVIRLLPAIVKWADSEIIKIESEYEKSRETKIKVLSISPSNGNKDPSKDNADQNV", "length": 152, "header": "tr|Q9VU49-1|Q9VU49_DROME Isoform 1 of ATP synthase subunit b OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG17300 PE=3 SV=1 CANONICAL=Q9VU49-1" }, "isoforms": [ { "isoform_ac": "Q9VU49-1", "url": "https://www.uniprot.org/uniprotkb/Q9VU49/entry#Q9VU49-1", "sequence": { "sequence": "MFSRLALRPLTVATSRSATTHSAQGLSRLPGHGSPGKVRPGFPSDNWVKGPMGVGLLAYICSGDCCAIKHEHSGLSLGIMEDGYYSSGITIGILTTFAVIRLLPAIVKWADSEIIKIESEYEKSRETKIKVLSISPSNGNKDPSKDNADQNV", "length": 152, "header": "tr|Q9VU49-1|Q9VU49_DROME Isoform 1 of ATP synthase subunit b OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG17300 PE=3 SV=1 CANONICAL=Q9VU49-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VU49", "url": "https://www.uniprot.org/uniprotkb/Q9VU49" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VU49", "url": "https://www.uniprot.org/uniprotkb/Q9VU49" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VU49", "url": "https://www.uniprot.org/uniprotkb/Q9VU49" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VU49", "url": "https://www.uniprot.org/uniprotkb/Q9VU49" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VU49", "url": "https://www.uniprot.org/uniprotkb/Q9VU49" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VU49", "url": "https://www.uniprot.org/uniprotkb/Q9VU49" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VU49", "url": "https://www.uniprot.org/uniprotkb/Q9VU49" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VU49", "url": "https://www.uniprot.org/uniprotkb/Q9VU49" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VU49", "url": "https://www.uniprot.org/uniprotkb/Q9VU49" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"MPAFMHLLRNFIPKWCLPRPEKHLQNHIFRQLQTNHPSAALVAIKTSEQVLPKCRFMQYRRANEQVKRLGMVSEDGSKMAELSSMTCAAPNMMDFIQQRYCMVSLLDSVQFMKIEDVEAVDLRLLPPIDSPSKIIGVDCNYVDNCDEQHISIPREPSFHVKFASSITGALDNIRAHSSAKHIDYGCQLAVVMGKRCREVSPKEALNHVFGFMVVQDIVARDWNVPLGGHSMDTFLPLGPTIVHRCHVPDLNNLWIKTIINGEERQTGNTRNMIFKIDFLIHRLSQYLTLCPGDIILTGTPAGSGAFRHPSCFLKPGDLIESEIQNLGKMCNKVVNSYS", "length": 338, "header": "tr|Q9VU50-1|Q9VU50_DROME Isoform 1 of Fumarylacetoacetase-like C-terminal domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG11251 PE=3 SV=1 CANONICAL=Q9VU50-1" }, "isoforms": [ { "isoform_ac": "Q9VU50-1", "url": "https://www.uniprot.org/uniprotkb/Q9VU50/entry#Q9VU50-1", "sequence": { "sequence": "MPAFMHLLRNFIPKWCLPRPEKHLQNHIFRQLQTNHPSAALVAIKTSEQVLPKCRFMQYRRANEQVKRLGMVSEDGSKMAELSSMTCAAPNMMDFIQQRYCMVSLLDSVQFMKIEDVEAVDLRLLPPIDSPSKIIGVDCNYVDNCDEQHISIPREPSFHVKFASSITGALDNIRAHSSAKHIDYGCQLAVVMGKRCREVSPKEALNHVFGFMVVQDIVARDWNVPLGGHSMDTFLPLGPTIVHRCHVPDLNNLWIKTIINGEERQTGNTRNMIFKIDFLIHRLSQYLTLCPGDIILTGTPAGSGAFRHPSCFLKPGDLIESEIQNLGKMCNKVVNSYS", "length": 338, "header": "tr|Q9VU50-1|Q9VU50_DROME Isoform 1 of Fumarylacetoacetase-like C-terminal domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG11251 PE=3 SV=1 CANONICAL=Q9VU50-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VU50", "url": "https://www.uniprot.org/uniprotkb/Q9VU50" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VU50", "url": "https://www.uniprot.org/uniprotkb/Q9VU50" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VU50", "url": "https://www.uniprot.org/uniprotkb/Q9VU50" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VU50", "url": "https://www.uniprot.org/uniprotkb/Q9VU50" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VU50", "url": "https://www.uniprot.org/uniprotkb/Q9VU50" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VU50", "url": "https://www.uniprot.org/uniprotkb/Q9VU50" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VU50", "url": "https://www.uniprot.org/uniprotkb/Q9VU50" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VU50", "url": "https://www.uniprot.org/uniprotkb/Q9VU50" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VU50", "url": "https://www.uniprot.org/uniprotkb/Q9VU50" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VU50", "url": "https://www.uniprot.org/uniprotkb/Q9VU50" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VU50", "url": "https://www.uniprot.org/uniprotkb/Q9VU50" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VU88-1", "uniprot_ac": "Q9VU88", "uniprot_id": "Q9VU88_DROME", "mass": { "chemical_mass": 75648.0, "monoisotopic_mass": 75648.0 }, "refseq": { "ac": "NP_001261806", "name": "Liprin-beta, isoform C", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261806" }, "gene_names": [ { "name": "Liprin-beta", "type": "recommended", "evidence": [ { "id": "Q9VU88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VU88" } ] }, { "name": "CG10743", "type": "synonym", "evidence": [ { "id": "NP_001261806", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261806" }, { "id": "Q9VU88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VU88" } ] }, { "name": "Dmel\\CG10743", "type": "synonym", "evidence": [ { "id": "NP_001261806", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261806" }, { "id": "Q9VU88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VU88" } ] }, { "name": "Dmel_CG10743", "type": "synonym", "evidence": [ { "id": "Q9VU88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VU88" } ] }, { "name": "Liprin-beta", "type": "synonym", "evidence": [ { "id": "NP_001261806", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261806" } ] }, { "name": "liprin", "type": "synonym", "evidence": [ { "id": "NP_001261806", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261806" }, { "id": "Q9VU88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VU88" } ] } ], "protein_names": [ { "name": "CG10743-PC", "type": "synonym", "evidence": [ { "id": "NP_001261806", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261806" } ] }, { "name": "Liprin-beta, isoform A", "type": "synonym", "evidence": [ { "id": "Q9VU88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VU88/entry#names_and_taxonomy" } ] }, { "name": "Liprin-beta, isoform B", "type": "synonym", "evidence": [ { "id": "Q9VU88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VU88/entry#names_and_taxonomy" } ] }, { "name": "Liprin-beta, isoform C", "type": "synonym", "evidence": [ { "id": "NP_001261806", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261806" }, { "id": "Q9VU88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VU88/entry#names_and_taxonomy" } ] }, { "name": "Liprin-beta-PC", "type": "synonym", "evidence": [ { "id": "NP_001261806", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261806" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], 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"https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09563", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09566", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09566", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09569", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09569", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0036376", "url": "https://flybase.org/reports/FBgn0036376", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "39524", "url": "https://www.ncbi.nlm.nih.gov/gene/39524", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VU88", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VU88*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR001660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029515", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029515", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037617", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037617", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037618", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037618", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037619", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037619", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058914", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058914", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG10743", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG10743", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KDHESSM", "url": "https://omabrowser.org/oma/group/KDHESSM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VU88", "url": "https://www.orthodb.org/?gene=Q9VU88", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12587", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12587", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12587:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12587:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00536", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00536", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07647", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07647", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26022", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26022", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-388844", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-388844", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001261806", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261806", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VU88", "url": "https://www.uniprot.org/uniprotkb/Q9VU88", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VU88-1", "url": "https://www.uniprot.org/uniprotkb/Q9VU88-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATVAEGSKMLEAALQQMDGLISSTATQAGSVSISGAGSSLTLSERNLISATNVLSTAKTLALALQQVGLAAPAPDPVTAAIISDWLETHIPRQDSDERMRRLQRDKEGLALQYQMLAERVSEQADKIIELEGLITEKSQQLCTKEEQLQRQMISSSALETQKLELMSALSELKLHRTALEQANDGGSAISANIPYGSLSNINQKAFMGSPKTPPSALRHQIKPQFHSLPRSHGKFVNNNNNRALDVNANSSGKQRNVAFASNEHILIDDNHHQAEDAMTSSFMSQFTPSPKLRERSARGLRNILGKLRRSNSSNCELTALEQAEPEFRRGGARATAGGRIEWSAQTPLFGENEKHWTTWGAQEVCNWLAYMGLGCYEDNCRKWLNANPSVSFFTASPVDIERELNLKMPLHRKKILLAIDDLTGKEFDDLTLKASSLDVTWVLRWLDDIGLPQYKDYFMQAKIDGRMLHRLTLEDLSQLHVSSCLHIASLRAGILCMRRLSWNAEGLIRRSIKVVSEDEAAATPDRDNVELWTAHRIMGWLQTIDLSEYTPNLRGAGVHGALMLYEPRFNADLLADLLSIPPSKSLLRRHLAMHFKELVGRPVILSKRDAESAPGYQPLSITAKLKPVKRTQFSLKRRKSSKSQSDVDWTEYVCPMNASVPETYLADTAKEHESSMSSN", "length": 680, "header": "tr|Q9VU88-1|Q9VU88_DROME Isoform 1 of Liprin-beta, isoform A OS=Drosophila melanogaster OX=7227 GN=Liprin-beta PE=3 SV=1 CANONICAL=Q9VU88-1" }, "isoforms": [ { "isoform_ac": "Q9VU88-1", "url": "https://www.uniprot.org/uniprotkb/Q9VU88/entry#Q9VU88-1", "sequence": { "sequence": "MATVAEGSKMLEAALQQMDGLISSTATQAGSVSISGAGSSLTLSERNLISATNVLSTAKTLALALQQVGLAAPAPDPVTAAIISDWLETHIPRQDSDERMRRLQRDKEGLALQYQMLAERVSEQADKIIELEGLITEKSQQLCTKEEQLQRQMISSSALETQKLELMSALSELKLHRTALEQANDGGSAISANIPYGSLSNINQKAFMGSPKTPPSALRHQIKPQFHSLPRSHGKFVNNNNNRALDVNANSSGKQRNVAFASNEHILIDDNHHQAEDAMTSSFMSQFTPSPKLRERSARGLRNILGKLRRSNSSNCELTALEQAEPEFRRGGARATAGGRIEWSAQTPLFGENEKHWTTWGAQEVCNWLAYMGLGCYEDNCRKWLNANPSVSFFTASPVDIERELNLKMPLHRKKILLAIDDLTGKEFDDLTLKASSLDVTWVLRWLDDIGLPQYKDYFMQAKIDGRMLHRLTLEDLSQLHVSSCLHIASLRAGILCMRRLSWNAEGLIRRSIKVVSEDEAAATPDRDNVELWTAHRIMGWLQTIDLSEYTPNLRGAGVHGALMLYEPRFNADLLADLLSIPPSKSLLRRHLAMHFKELVGRPVILSKRDAESAPGYQPLSITAKLKPVKRTQFSLKRRKSSKSQSDVDWTEYVCPMNASVPETYLADTAKEHESSMSSN", "length": 680, "header": "tr|Q9VU88-1|Q9VU88_DROME Isoform 1 of Liprin-beta, isoform A OS=Drosophila melanogaster OX=7227 GN=Liprin-beta PE=3 SV=1 CANONICAL=Q9VU88-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VU88", "url": "https://www.uniprot.org/uniprotkb/Q9VU88" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VU88", "url": "https://www.uniprot.org/uniprotkb/Q9VU88" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VU88", "url": "https://www.uniprot.org/uniprotkb/Q9VU88" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VU88", "url": "https://www.uniprot.org/uniprotkb/Q9VU88" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VU88", "url": "https://www.uniprot.org/uniprotkb/Q9VU88" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VU88", "url": "https://www.uniprot.org/uniprotkb/Q9VU88" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VU88", "url": "https://www.uniprot.org/uniprotkb/Q9VU88" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VU88", "url": "https://www.uniprot.org/uniprotkb/Q9VU88" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VU88", "url": "https://www.uniprot.org/uniprotkb/Q9VU88" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VU88", "url": "https://www.uniprot.org/uniprotkb/Q9VU88" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VU88", "url": "https://www.uniprot.org/uniprotkb/Q9VU88" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG10743", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG10743", "resource": "KEGG Pathway" }, { "id": "R-DME-388844", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-388844", "resource": "Reactome", "description": "Receptor-type tyrosine-protein phosphatases" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0J9YJ57-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "ppfibp1a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMCDASEMLAAALEQMDGIIAGSKAMTYTNGLFDCQSPTSPFLGSIRALHLLEDLRAALDLMDPEEKENMRSQVSETTAEGLMEWLQGRLTNGHGSAAGDLVHQERLSRLESDKECLVLQVSVLTDQVEVQGEKIRDLDSSLEEHHMKLNATEELLQQELLSRSTLEAEKLELLTEISSLKLKLAAAEGDCRECEGLFQDVKDLRLKLTSMENERQHYERSLISTKEELISLQKQLEEREQAFKRIQDRGVPETLNTEQSQSKERDVEVQRLRSAMESLKATNEEKDFRIKELQQSLIHYRRVQDIGKTVHVLKDNLSDEDTREGLCDSEMLSTGGTEETDEPQLIPCSELLPEVPHTPTDSVSEVQQSERSPLTSSNEDEASKNRGFPSISPTQPSSGRNESFGSKKTRSSFGRGFFKIRGNKMTGSAPSLAEGEQKGTEHLDLAGVQTKKQKALDTHSPDGKKKSKGIMKLFGRMKRSQSTSSDLDDSPDSEFQRGGVRATAGPRLGWSRDLQRSNNNELNSAFSRWSKEQVCEWLQEQGLGLYMNQAQQWIKSGHTLLKASQHDWEKELGIRHPLHRKKLQLALQSLSSEDGDAMGKLDYNWVTQWLDDIGLPQYKSQFDEGRVDGRMLHYMTVDDLLGLKVGSVLHHLSIKRAIQVLRLNGYDPNCLRRRPIENNATPAEICQWTNHRVMEWLRSVDLAEYAPNLRGSGVHGGLMVLEPRFNVETMALLLNIPPNKTLLRRHLATHFHLLIGSEAQKQKQEYLENPDYTVLTATARVKPRRLSFGSFGTLRRKRQEDMEEYVCPMDVQMPQSSSFHKGIYEDSLDKLEQMEDSEGTVRQIGAFSEEINNLTSMLKEEEFFREASPHSPETSATDDD", "length": 880 }, "evidence": [ { "id": "HGNC:9249", "url": "https://alliancegenome.org/gene/HGNC:9249#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8I5ZVX1-1", "protein_name": "PPFIA binding protein 2", "gene_name": "Ppfibp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTSDASHMLEAALEQMDGIIAGTKTAADFSDGTCEPGLSPPSSCLNSMPVLHLIEDLRLALEMLALPQEREALLSQIPGPTAAYIKEWFEDSLSQVNHHSAASNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQKEQEEKQRKAESVLNVISELQEQMCRLQLDIHRQIQERLLLARDHPEEVVAGDHEAKPQPCSRDCAPWEGSPELLQELKHLKIKVEELENERNQYEWELKATKAEVAQLQEQVALKDAEIERLHSQLSRSSALHSDHAERDQEIHRLKMGMETLRVANEDKDRRIEELTGLLNQYLRVKEIVMATQGSSERTLSINEDEIEGSFRKWNTTSKSPEEVMKQEVSPRCSSPTPGPPPLPQKSLETRAQKKLSCSLEDLRCESGNKCINGNQTSPVGEPKDSSFLAEQKYPTLPGKLSGATPNGEAAKSPPTASLQPDSSGSSQPKLNRGWSISAPVLGDTEGGWEDIVMTNELSSTSSGTESSPQSPLTPDGKRSPKGIKKFWGKIRRTQSGNFNTDTPGMVEFRRGGLRATAGPRLSRTRDTKGQKCDANAPFAQWSTERVCTWLQDFGLAQYVIFARQWVASGHTLLTATPQDMEKELGIKHPLHRKKLVLAVKAINTKQEEKSALLDHVWVTRWLDDIGLPQYKDQFYESRVDGRMLQYLTVNDLLFLKVTSQLHHLSIKCAIHVLHVNKFNPNCLHRRPADESNLSPSEVVQWSNHRVMEWLRSVDLAEYAPNLRGSGVHGGLIILEPRFTGDTLAMLLNIPPQKTLLRRHLTTKFNALIGPEAEQEKRDKMASPAYTPLTTTAKVRPRKLGFSHFGNMRKKKFDESTDYICPMEPGDAVSDSHRVYGVYRGLSPLDNHELDGLDQMAPSEGTVTQIGLLSQDIHRLTTLLSQDQLLNDPPGCP", "length": 981 }, "evidence": [ { "id": "HGNC:9250", "url": "https://alliancegenome.org/gene/HGNC:9250#orthology", "database": "AGR" }, { "id": "MGI:894649", "url": "https://alliancegenome.org/gene/MGI:894649#orthology", "database": "AGR" }, { "id": "RGD:1565383", "url": "https://alliancegenome.org/gene/RGD:1565383#orthology", "database": "AGR" }, { "id": "FB:FBgn0036376", "url": "https://alliancegenome.org/gene/FB:FBgn0036376#orthology", "database": "AGR" }, { "id": "Q9VU88", "url": "https://omabrowser.org/oma/group/Q9VU88/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ATF2-1", "protein_name": "PPFIA binding protein 1", "gene_name": "Ppfibp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGSLRALHLVEDLRGLLEMMETDEKEGLRCQIPDSTAEMLIEWLQNQMTNGHLPGNGDVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKLNATEEMLQQELLSRTSLETQKLELMAEISNLKLKLTAVEKDRLDYEDRFRDTEGLIQEINDLRLKVNEMDSERLQYEKKLKSTKSLMAKLSSMKIKVGQMQYEKQRMEQKWETLKDELASLKEQLEEKECEVKRLQERLVCKTKGEGVEILDRDENIKRKLKEKNIEVQKMKKAVESLMAANEEKERKIEDLRQCLSRYRKVQDPAALAQGQEGECEGLFHSSSISTLLDAQGFSDLERSTSSTPGMGSPSRDPLHTSAPEEFHTSVLQASVPSLFPTSMDEETCEKPKLATKPETSFEEGDGRAVLGADAEVSLSDGVSTSSLQKSSSLGNLKKETSDGVDKTPTDSHTFGTLPPKAPGHGASVDDSPFGTRKARSSFGRGFFKIKSGKRTASAPNLDRKRSASAPTLAETEKETDEHLDLAGTSRPKGSQGTSPFQMSPPSPDSRKKSRGIMRLFGKLRRSQSTTFNPDDMSEPEFKRGGTRATAGPRLGWSRDLGQSNSDLDTPFAKWTKEQVCSWLAEQGLGSYLSSGKHWIMSGQTLLQASQQDLEKELGIKHSLHRKKLQLALQALGSEEETNYGKLDFNWVTRWLDDIGLPQYKTQFDEGRVDGRMLHYMTVDDLLSLKVVSVLHHLSIKRAIQVLRINNFEPNCLRRRPSDENSITPSEVQQWTNHRVMEWLRSVDLAEYAPNLRGSGVHGGLMVLEPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLIGAEAQHQKRDAMELPDYVLLTATAKVKPKKLTFSNFGNLRKKKHEDGEEYVCPMELGQASGSSQKGFRPGLDMRLYEEDDLDRLEQMEDSEGTVRQIGAFSEGINNLTHMLKEDDMFKDFAARSPSASITDEDSNV", "length": 1022 }, "evidence": [ { "id": "RGD:1310010", "url": "https://alliancegenome.org/gene/RGD:1310010#orthology", "database": "AGR" }, { "id": "HGNC:9249", "url": "https://alliancegenome.org/gene/HGNC:9249#orthology", "database": "AGR" }, { "id": "MGI:1914783", "url": "https://alliancegenome.org/gene/MGI:1914783#orthology", "database": "AGR" }, { "id": "FB:FBgn0036376", "url": "https://alliancegenome.org/gene/FB:FBgn0036376#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AB32TAE7-1", "protein_name": "Liprin-beta-2 isoform X1", "gene_name": "ppfibp2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLRNLNQRLNPDERRRLVVCTLKVNVHSACNGETYQERLSRLEGDKESLVLQVSVLTDQVEAQGAKIRDLENSLGEYQHKLNSTEEMLQQEFFSRSSLESQKLGLMEEVSCLKLKLGDMEDKHINCAERQHKAESVVNLISELQEQMCRIRQEISSKNPEKPAEMIPEEGYGSEPAQASQTEPKPTNLLQELKILKHRVEELEQEKTHYEQKLKVTQAEIMTLQQLLNCKNSEIENLQAQLLSRAPVSVDSAEREEIYRRRLNTKHQELQRLKTGMESLIAANDEKDRQIEELTLLLSQFKQMNEIMTLVQGTEDKSIQIRSEDEKQNGAVKMKTLIQKAHPELTFSSSTPLLFSSVSSQKDANSRSNSIEDFNGSSTPKTGQADNKHQTLPAVTLPEKREGETSDTSGKKSPENKDEDINIKTMKDTTNSDLSSVSSGAESGQQSPVSQENVKNTSIRKLWGKMKRTGVLSDDLEPTQFKRGGFRATAGPRLIRTPDSGRSSRSQTPFCKWTTEQVCGWMEECGLGQYVSLARQWVDSGQTLLSATPQELEKEICIKHPLHRKKLQLALRAFSNKTMEKSSELDHIWVTRWLDDIGLPQYKDQFYESKVDGRMLQYLTVNDLLFLKVTSQLHHLSIKCAIHVLHVNKFNPNCLRRRPGDEFKTSPSEVVQWSNHRVMEWLRSVDLAEYAPNLRGSGVHGGLIILEPRFHSETLALLLNIPPQKTLLRRHLATNFYTLVGLQAQQEKREFANASGHAPLTTTAKVRPKKLGFTHFRQLRKLKMDESADYICPMDTGTSPVLNGTPKKHYASFRGISPILARESDRLEQVGSKG", "length": 833 }, "evidence": [ { "id": "HGNC:9250", "url": "https://alliancegenome.org/gene/HGNC:9250#orthology", "database": "AGR" }, { "id": "MGI:894649", "url": "https://alliancegenome.org/gene/MGI:894649#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QB48-1", "protein_name": "Liprin-beta-2b isoform 1", "gene_name": "ppfibp2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASDASHMLEAALEQMDDIIAGSKAVAELSNGLYDLGSPVSVGPLQILQLAEELRLALELQAGDEERHSLRSQLPCSTAHTLLHWLDRGALSQVNHQSSSNNETYQERLARLEGDKESLVLQVSVLTDQVEAQGEKIRDLESSLEEHHHKLISTEEMLQQELFSRTSLETQKLELMDEVSYLKLKLVGMEEEHNHIDEEDKHHKAESVVNLISELQEQMCKFQEEISNRIQEQRALESLGDSGTREALDQSPDVGLGASDAEDCSCRCRSGGENALLQELRLLKNKVEELEGEKSQYERKLKATKTEIAKLQQLLATKDAEIECLQNQLLSRGTINNDITERDQELQRLKTGMETLIAANNEKDRHIEELNVLLGQYRKLKDGLALSQVNNDSLLCGSSEEDLSGNRKIRALTHKAYSDIIRSELQMSSRGPSPFLVSPPCLQRDLDSRSLQRMLSSSLEELQSGSLQMHVVERPVEAALENRYNPENNKYQTLPGKLNRPDQNGLRLQCSPLLISPDDSEDSQFNLRKIEKADDSTLSDLSPLSSGVESGQQSPVSPEHKKNQKGIRKLWGKIRRTQSGSLPADSDSDFKRGGFRATAGPRLTCLGISTSSRDTNAPFSKWSCDQVCTWMEDFGLGQYVNMARQWVTSGQSLLSASSHEIEKELGIKHPLHRKKLQLALHSFSSKITEKSSELDYIWVTRWLDDIGLPQYKDQFNEGRVDGRMLQYLTVNDLLFLKVTSQLHHLSIKCAIHVLHVNKFNPNCLKRRPGDENKTSPSEVVQWSNHRVMEWLRSVDLAEYAPNLRGSGVHGGLIILEPRFNSDTLAMLLNIPPQKTLLRRHLATNFNTLVGSQAQQEKQEFLESSGYTPLTTTAKVRPRKIGFSSFGPRKKRSDDSTDYICPLDASQAQALLNGANRPYSGFRGLSPIFDRDPERREQILHAKGSGMQIEALSKGINNLTYLLSRDELLRGMRRSQTAIV", "length": 979 }, "evidence": [ { "id": "HGNC:9250", "url": "https://alliancegenome.org/gene/HGNC:9250#orthology", "database": "AGR" }, { "id": "MGI:894649", "url": "https://alliancegenome.org/gene/MGI:894649#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O35711-1", "protein_name": "Liprin-beta-2", "gene_name": "Ppfibp2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSDASHMLEAALEQMDGIIAGTKTAADFSDGTCEPGLSPPSTCLNSMPVLHLIEDLRLALEMLALPQEREALLSQVPGPTATYIKEWFEDSLSQVNHHGAASNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQKEQEEKQRKAEELLQELKHLKIKVEELENERNQYEWELKATKAEVAQLQEQVALKDAEIERLHSQLSRSAALHSDHAERDQEIHRLKMGMETLLVANEDKDRRIEELTGLLNKYLRVKEIVMATQGPSERTLSINEDEIEGSFRKWNTTNKSPEEVPKQEISPRCSSPTPGPPPLPQKSLESRAQKKLSCSLEDLRRESGDKCVDGNQLSPVGEPKDSSFLAEQKYPTLPGKLSGATPNGEAAKSPPTASLQPDSSGSSQPKLNRGWSVSAPVLRDTEGGWEDIVSSASSGTESSPQSPVTPDGKRSPKGIKKFWGKIRRTQSGNFNTDAPGMAEFRRGGLRATAGPRLSRTRDTKGQKCDANAPFAQWSTERVCTWMEDFGLGQYVIFARQWVTSGHTLLTATPQDMEKELGIKHPLHRKKLVLAVKAINAKQEETSALLDHIWVTRWLDDIGLPQYKDQFHESRVDGRMLQYLTVNDLLFLKVTSQLHHLSIKCAIHVLHVNKFNPNCLHRRPADESNLSPSEVVQWSNHRVMEWLRSVDLAEYAPNLRGSGVHGGLIILEPRFTGDTLAMLLNIPPQKTLLRRHLTTKFNALIGPEAEQEKRDKMASPAYTPLTTTAKVRPRKLGFSHFGNMRKKKFDESTDYICPMEPGDAVSDSHRVYGVYRGLSPLDNHELDGLDQVGQIS", "length": 882 }, "evidence": [ { "id": "HGNC:9250", "url": "https://alliancegenome.org/gene/HGNC:9250#orthology", "database": "AGR" }, { "id": "MGI:894649", "url": "https://alliancegenome.org/gene/MGI:894649#orthology", "database": "AGR" }, { "id": "RGD:1565383", "url": "https://alliancegenome.org/gene/RGD:1565383#orthology", "database": "AGR" }, { "id": "FB:FBgn0036376", "url": "https://alliancegenome.org/gene/FB:FBgn0036376#orthology", "database": "AGR" }, { "id": "Q9VU88", "url": "https://omabrowser.org/oma/group/Q9VU88/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q1LUM4-1", "protein_name": "Liprin-beta-1b", "gene_name": "ppfibp1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMSDASDMLAAALEQMDGIIAGSKALDYSNGIFDCQSPTSPFMGSLRALNLLEDLRGILELMETEERESLRCQIPDSTADSLVEWLHGHLSNGHISISGDVYQDRLNRLESDKESLVLQVSVLTDQVDAQGEKIRDLDLCLDEHREKLNATEEMLQQELLCRSALETQKLELMTEVSNLKLKLAAMDKERLDFDERFGDEGLILEINELRYRISEMENERLQYEKKLKSTKSLMAKLSSLKLKMGQMQYEKQRKEQKIEALKEELVSLRRQQEGRDGVDLRRLQDESGSRSSTPAGLDGTERVYVMLNVSLRVNVLTFSVSEMDFSLLSLCFADMEVQKMKKAMESLMAANEEKDRKIEELRQSLMRYKKVQEMVMSAHGRKEKVKEGDSDESNSDSSLSMSTALSFSIDTDKSLLAYTEEAARAQNEASTFVSTLQVPSLTVSSPDKADSDSVLEHMQSSDKECEEPDQSQETPLHESPESSEVTKSGSQGNLDGGTSEKSKKFDEFNKITTLPPKSTSSSGTAEDDSFGTRKMRSSFGRGFFKLKGGKRTASAPNLSETERDGTDHLDLAGLPQRSADSDSTHTLPISPEGKKKSKGFKALFGKLKRSQSTTFNLDDNLSESEFKRGGVRATAGPRLGWSRDLQNTNSDLDAPFARWSREQVCDWMQEQGLGLYVTLARQWVSSGQTLLQASQHDLERELGIKHPLHRKKLQLALQALGSEEDDNKGKLDYHWVTRWLDDIGLPQYKTQFDEGRVDGRMLHYMTVDDLLSLKVGSVLHHLSIKRAIQVLRLNNYDPNCLRRRPSDENNISPAEISQWTNHRVMEWLRSVDLAEYAPNLRGSGVHGGLMVLEPRFNVETMALLLNIPPNKTLLRRHLATHFNLLVGSEAQQLKQECLENPDYALLTATAKVKPHKLAFVGFGRKKKQEDNEEYVCPMDVEMPKGRSFQKGYRGMELQIYDDDLDRLDQMEDSEGTVRQIGAFSEGINNLTSMLKDDEFFFPNASVKDDDSNV", "length": 1013 }, "evidence": [ { "id": "HGNC:9249", "url": "https://alliancegenome.org/gene/HGNC:9249#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q86W92-1", "protein_name": "Liprin-beta-1", "gene_name": "PPFIBP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGSLRALHLVEDLRGLLEMMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKSLMAKLSSMKIKVGQMQYEKQRMEQKWESLKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVDRDIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGKDGEYEELLNSSSISSLLDAQGFSDLEKSPSPTPVMGSPSCDPFNTSVPEEFHTTILQVSIPSLLPATVSMETSEKSKLTPKPETSFEENDGNIILGATVDTQLCDKLLTSSLQKSSSLGNLKKETSDGEKETIQKTSEDRAPAESRPFGTLPPRPPGQDTSMDDNPFGTRKVRSSFGRGFFKIKSNKRTASAPNLAETEKETAEHLDLAGASSRPKDSQRNSPFQIPPPSPDSKKKSRGIMKLFGKLRRSQSTTFNPDDMSEPEFKRGGTRATAGPRLGWSRDLGQSNSDLDMPFAKWTKEQVCNWLMEQGLGSYLNSGKHWIASGQTLLQASQQDLEKELGIKHSLHRKKLQLALQALGSEEETNHGKLDFNWVTRWLDDIGLPQYKTQFDEGRVDGRMLHYMTVDDLLSLKVVSVLHHLSIKRAIQVLRINNFEPNCLRRRPSDENTIAPSEVQKWTNHRVMEWLRSVDLAEYAPNLRGSGVHGGLMVLEPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLIGAEAQHQKRDAMELPDYVLLTATAKVKPKKLAFSNFGNLRKKKQEDGEEYVCPMELGQASGSASKKGFKPGLDMRLYEEDDLDRLEQMEDSEGTVRQIGAFSEGINNLTHMLKEDDMFKDFAARSPSASITDEDSNV", "length": 1011 }, "evidence": [ { "id": "RGD:1310010", "url": "https://alliancegenome.org/gene/RGD:1310010#orthology", "database": "AGR" }, { "id": "HGNC:9249", "url": "https://alliancegenome.org/gene/HGNC:9249#orthology", "database": "AGR" }, { "id": "MGI:1914783", "url": "https://alliancegenome.org/gene/MGI:1914783#orthology", "database": "AGR" }, { "id": "FB:FBgn0036376", "url": "https://alliancegenome.org/gene/FB:FBgn0036376#orthology", "database": "AGR" }, { "id": "Q9VU88", "url": "https://omabrowser.org/oma/group/Q9VU88/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8C8U0-1", "protein_name": "Liprin-beta-1", "gene_name": "Ppfibp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGSLRALHLVEDLRGLLEMMETDEKEGLRCQIPDSTAEVLIEWLQNQMTNGHLPGNGDVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKLNATEEMLQQELLSRTSLETQKLELMAEISNLKLKLTAVEKDRLDYEDRFRDTEGLIQEINDLRLKVNEMDGERLQYEKKLKSTKDELASLKEQLEEKECEVKRLQERLVCKAKGEGIEVLDRDIEVQKMKKAVESLMAANEEKERKIEDLRQCLSRYRKMQDPAVLAQGQDSECEGLFHSSSISTLLDAQGFSDLERSTSSTPGMGSPSRDLLHTSAPEEFHTSVLQASIPSLLPPSVDVDTCEKPKLPTKPETSFEEGDGRAILGAAAEVSLSDGVSTSSLQKSSSLGNLKKEASDGTDKAPTDSRTFGTLPPKVPGHEASVDDNPFGTRKARSSFGRGFFKIKSGKRTASAPNLAETEKETAEHLNLAGTSRSKGSQGTSPFPMSPPSPDSRKKSRGIMRLFGKLRRSQSTTFNPDDMSEPEFKRGGTRATAGPRLGWSRDLGQSNSDLDMPFAKWTKEQVCSWLAEQGLGSYLSSGKHWIISGQTLLQASQQDLEKELGIKHSLHRKKLQLALQALGSEEETNYGKLDFNWVTRWLDDIGLPQYKTQFDEGRVDGRMLHYMTVDDLLSLKVVSVLHHLSIKRAIQVLRINNFEPNCLRRRPSDENSITPSEVQQWTNHRVMEWLRSVDLAEYAPNLRGSGVHGGLMVLEPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLIGAEAQHQKRDAMELPDYVLLTATAKVKPKKLTFSNFGNLRKKKHEDGEEYVCPMELGQASGSSQKGFRPGLDMRLYEEDDLDRLEQMEDSEGTVRQIGAFSEGINNLTHMLKEDDMFKDFAARSPSASITDEDSNV", "length": 969 }, "evidence": [ { "id": "RGD:1310010", "url": "https://alliancegenome.org/gene/RGD:1310010#orthology", "database": "AGR" }, { "id": "HGNC:9249", "url": "https://alliancegenome.org/gene/HGNC:9249#orthology", "database": "AGR" }, { "id": "MGI:1914783", "url": "https://alliancegenome.org/gene/MGI:1914783#orthology", "database": "AGR" }, { "id": "FB:FBgn0036376", "url": "https://alliancegenome.org/gene/FB:FBgn0036376#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8ND30-1", "protein_name": "Liprin-beta-2", "gene_name": "PPFIBP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASDASHALEAALEQMDGIIAGTKTGADLSDGTCEPGLASPASYMNPFPVLHLIEDLRLALEMLELPQERAALLSQIPGPTAAYIKEWFEESLSQVNHHSAASNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLNAAEEMLQQELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELLQELRHLKIKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHSQLSRTAALHSESHTERDQEIQRLKMGMETLLLANEDKDRRIEELTGLLNQYRKVKEIVMVTQGPSERTLSINEEEPEGGFSKWNATNKDPEELFKQEMPPRCSSPTVGPPPLPQKSLETRAQKKLSCSLEDLRSESVDKCMDGNQPFPVLEPKDSPFLAEHKYPTLPGKLSGATPNGEAAKSPPTICQPDATGSSLLRLRDTESGWDDTAVVNDLSSTSSGTESGPQSPLTPDGKRNPKGIKKFWGKIRRTQSGNFYTDTLGMAEFRRGGLRATAGPRLSRTRDSKGQKSDANAPFAQWSTERVCAWLEDFGLAQYVIFARQWVSSGHTLLTATPQDMEKELGIKHPLHRKKLVLAVKAINTKQEEKSALLDHIWVTRWLDDIGLPQYKDQFHESRVDRRMLQYLTVNDLLFLKVTSQLHHLSIKCAIHVLHVNKFNPHCLHRRPADESNLSPSEVVQWSNHRVMEWLRSVDLAEYAPNLRGSGVHGGLIILEPRFTGDTLAMLLNIPPQKTLLRRHLTTKFNALIGPEAEQEKREKMASPAYTPLTTTAKVRPRKLGFSHFGNIRKKKFDESTDYICPMEPSDGVSDSHRVYSGYRGLSPLDAPELDGLDQVGQIS", "length": 876 }, "evidence": [ { "id": "HGNC:9250", "url": "https://alliancegenome.org/gene/HGNC:9250#orthology", "database": "AGR" }, { "id": "MGI:894649", "url": "https://alliancegenome.org/gene/MGI:894649#orthology", "database": "AGR" }, { "id": "RGD:1565383", "url": "https://alliancegenome.org/gene/RGD:1565383#orthology", "database": "AGR" }, { "id": "FB:FBgn0036376", "url": "https://alliancegenome.org/gene/FB:FBgn0036376#orthology", "database": "AGR" }, { "id": "Q9VU88", "url": "https://omabrowser.org/oma/group/Q9VU88/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "neuromuscular junction development", "id": "GO:0007528", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007528", "evidence": [ { "database": "UniProtKB", "id": "Q9VU88", "url": "https://www.uniprot.org/uniprotkb/Q9VU88" } ], "pmid": "" }, { "name": "synaptic assembly at neuromuscular junction", "id": "GO:0051124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051124", "evidence": [ { "database": "UniProtKB", "id": "Q9VU88", "url": "https://www.uniprot.org/uniprotkb/Q9VU88" } ], "pmid": "" }, { "name": "regulation of synapse assembly", "id": "GO:0051963", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051963", "evidence": [ { "database": "UniProtKB", "id": "Q9VU88", "url": "https://www.uniprot.org/uniprotkb/Q9VU88" } ], "pmid": "" }, { "name": "axon target recognition", "id": "GO:0007412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007412", "evidence": [ { "database": "UniProtKB", "id": "Q9VU88", "url": "https://www.uniprot.org/uniprotkb/Q9VU88" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "neuromuscular junction", "id": "GO:0031594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031594", "evidence": [ { "database": "UniProtKB", "id": "Q9VU88", "url": "https://www.uniprot.org/uniprotkb/Q9VU88" } ], "pmid": "" }, { "name": "presynaptic active zone", "id": "GO:0048786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048786", "evidence": [ { "database": "UniProtKB", "id": "Q9VU88", "url": "https://www.uniprot.org/uniprotkb/Q9VU88" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "Q9VU88", "url": "https://www.uniprot.org/uniprotkb/Q9VU88" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "Q9VU88", "url": "https://www.uniprot.org/uniprotkb/Q9VU88" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 250, "end_pos": 252, "annotation": "n_glycosylation_sequon" }, { "start_pos": 312, "end_pos": 314, "annotation": "n_glycosylation_sequon" }, { "start_pos": 658, "end_pos": 660, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VU88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VU88" }, { "id": "PS50105", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50105" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SAM", "eco_id": "ECO_0000259", "start_pos": 360, "end_pos": 426, "start_aa": "Trp", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 250, "end_pos": 252 }, { "start_pos": 312, "end_pos": 314 }, { "start_pos": 658, "end_pos": 660 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VUA5-1", "uniprot_ac": "Q9VUA5", "uniprot_id": "Q9VUA5_DROME", "mass": { "chemical_mass": 106568.0, "monoisotopic_mass": 106568.0 }, "refseq": { "ac": "NP_001287065", "name": "short spindle 2, isoform C", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287065" }, "gene_names": [ { "name": "ssp2", "type": "recommended", "evidence": [ { "id": "Q9VUA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUA5" } ] }, { "name": "CG9028", "type": "synonym", "evidence": [ { "id": "NP_001287065", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287065" }, { "id": "Q9VUA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUA5" } ] }, { "name": "Dmel\\CG9028", "type": "synonym", "evidence": [ { "id": "NP_001287065", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287065" }, { "id": "Q9VUA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUA5" } ] }, { "name": "Dmel_CG9028", "type": "synonym", "evidence": [ { "id": "Q9VUA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUA5" } ] }, { "name": "Sentin", "type": "synonym", "evidence": [ { "id": "NP_001287065", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287065" }, { "id": "Q9VUA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUA5" } ] }, { "name": "Ssp2", "type": "synonym", "evidence": [ { "id": "NP_001287065", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287065" }, { "id": "Q9VUA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUA5" } ] }, { "name": "sentin", "type": "synonym", "evidence": [ { "id": "NP_001287065", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287065" }, { "id": "Q9VUA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUA5" } ] }, { "name": "ssp2", "type": "synonym", "evidence": [ { "id": "NP_001287065", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287065" } ] } ], "protein_names": [ { "name": "CG9028-PC", "type": "synonym", "evidence": [ { "id": "NP_001287065", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287065" } ] }, { "name": "Short spindle 2, isoform A", "type": "synonym", "evidence": [ { "id": "Q9VUA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUA5/entry#names_and_taxonomy" } ] }, { "name": "Short spindle 2, isoform C", "type": "synonym", "evidence": [ { "id": "Q9VUA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUA5/entry#names_and_taxonomy" } ] }, { "name": "sentin", "type": "synonym", "evidence": [ { "id": "NP_001287065", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287065" } ] }, { "name": "short spindle 2, isoform C", "type": "synonym", "evidence": [ { "id": "NP_001287065", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287065" } ] }, { "name": "short spindle", "type": "synonym", "evidence": [ { "id": "NP_001287065", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287065" } ] }, { "name": "ssp2-PC", "type": "synonym", "evidence": [ { "id": "NP_001287065", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287065" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VUA5", "url": "https://www.uniprot.org/uniprotkb/Q9VUA5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "ssp2", "url": "https://www.uniprot.org/uniprotkb/Q9VUA5", "locus": { "chromosome": "3L", "start_pos": 13973067, "end_pos": 13965203, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0036389", "url": "https://www.ensemblgenomes.org/id/FBgn0036389" } ] } } ], "crossref": [ { "id": "FB:FBgn0036389", "url": "https://alliancegenome.org/gene/FB:FBgn0036389", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0036389", "url": "https://bgee.org/?page=gene&gene_id=FBgn0036389", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0036389", "url": "https://flybase.org/reports/FBgn0036389", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "39540", "url": "https://www.ncbi.nlm.nih.gov/gene/39540", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dme:Dmel_CG9028", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG9028", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MRDDSQQ", "url": "https://omabrowser.org/oma/group/MRDDSQQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VUA5", "url": "https://www.orthodb.org/?gene=Q9VUA5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "NP_001287065", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287065", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VUA5", "url": "https://www.uniprot.org/uniprotkb/Q9VUA5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VUA5-1", "url": "https://www.uniprot.org/uniprotkb/Q9VUA5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDILDIDEALKDDSYIFLADKTHDDVSNILQQWKTNNQPPLQQLHLQYNNEAFKNNSKTFTRPKRRNLDFSQNGAGNDSGVGTGSVAGAPAMLQLEIGGLVTTNMHKSFLQDTSPPSSICSSMNTERMNNSLITSADFTNLNFLQSTIGLEQDPNLTTTLTNQTTDNMGIGGSIGGYTLSDMIRDRKALESLTMCEDDGTLIKDSHIGQIDEISLTLSKTASGCSTMDNSTDSMSIPLAADRTMPVVVSAVCPALQRTMILGEEMIGDTTFNLVDSLTTSALQSESESLPVDGNATFKRPTASATTADETQVLTGRQMNTTFTDGCNTPEGRCETPENIDRKLALLTMESSTPLTTNMRSHCYHNNNNNNKAGYTPTLKGRGDMNLSPIVGATPQKPTGTAPGRLNNTFEPVAKTAPFNGEKFVLDTMELLEQIEQPLDGTYNLQMSEQHRQMQCVMDLAEAEVEMLAQQGDEEQFENMLAELGKVNTLNEEQLKMQKSLDTIKRRFHRDEAEAEEREEELQQSAAEKVDTPVLNQSHSSSNSSGGGGERLLSRRSRLYDDVNLSAMHGSNGSSTSTNSASFIVQRRDMPQVEQPAPDPDPEPAEEPPKSQVTAEIDPASYKLPERRERDRDRFKTIKISKEMRLQPEIIVPCIDDEPQQLEDEQKQLVEDVRYEEDQRQGSPPGRLSRRDQTTAISNNADASASNYLTYKKPKEKSLIQRRPQQQEAPLLAEPAPASTLPQPRSLSRPRYISGLQKFTTVSKATSAGAGLNATPAAAMPTTVTVPANGNGELKSPMGIKSKSFHNLSSTMSGVGSGALPRPSLGGGLRRPSAQPSKLMSGLRGPTQAQEDDSAVFKVPKLVSGLRAPGLAPKRAGANGLARPSSGYYSLSVKTAPEADTPESLSSASSRGSLYGHKDSGRTVNGGNVPQQNPQQTFDMQALTSKLTQVTTGATGIPKPSGLRPPSQIKRSGLPRPSSIVRR", "length": 982, "header": "tr|Q9VUA5-1|Q9VUA5_DROME Isoform 1 of Short spindle 2, isoform C OS=Drosophila melanogaster OX=7227 GN=ssp2 PE=1 SV=1 CANONICAL=Q9VUA5-1" }, "isoforms": [ { "isoform_ac": "Q9VUA5-1", "url": "https://www.uniprot.org/uniprotkb/Q9VUA5/entry#Q9VUA5-1", "sequence": { "sequence": "MDILDIDEALKDDSYIFLADKTHDDVSNILQQWKTNNQPPLQQLHLQYNNEAFKNNSKTFTRPKRRNLDFSQNGAGNDSGVGTGSVAGAPAMLQLEIGGLVTTNMHKSFLQDTSPPSSICSSMNTERMNNSLITSADFTNLNFLQSTIGLEQDPNLTTTLTNQTTDNMGIGGSIGGYTLSDMIRDRKALESLTMCEDDGTLIKDSHIGQIDEISLTLSKTASGCSTMDNSTDSMSIPLAADRTMPVVVSAVCPALQRTMILGEEMIGDTTFNLVDSLTTSALQSESESLPVDGNATFKRPTASATTADETQVLTGRQMNTTFTDGCNTPEGRCETPENIDRKLALLTMESSTPLTTNMRSHCYHNNNNNNKAGYTPTLKGRGDMNLSPIVGATPQKPTGTAPGRLNNTFEPVAKTAPFNGEKFVLDTMELLEQIEQPLDGTYNLQMSEQHRQMQCVMDLAEAEVEMLAQQGDEEQFENMLAELGKVNTLNEEQLKMQKSLDTIKRRFHRDEAEAEEREEELQQSAAEKVDTPVLNQSHSSSNSSGGGGERLLSRRSRLYDDVNLSAMHGSNGSSTSTNSASFIVQRRDMPQVEQPAPDPDPEPAEEPPKSQVTAEIDPASYKLPERRERDRDRFKTIKISKEMRLQPEIIVPCIDDEPQQLEDEQKQLVEDVRYEEDQRQGSPPGRLSRRDQTTAISNNADASASNYLTYKKPKEKSLIQRRPQQQEAPLLAEPAPASTLPQPRSLSRPRYISGLQKFTTVSKATSAGAGLNATPAAAMPTTVTVPANGNGELKSPMGIKSKSFHNLSSTMSGVGSGALPRPSLGGGLRRPSAQPSKLMSGLRGPTQAQEDDSAVFKVPKLVSGLRAPGLAPKRAGANGLARPSSGYYSLSVKTAPEADTPESLSSASSRGSLYGHKDSGRTVNGGNVPQQNPQQTFDMQALTSKLTQVTTGATGIPKPSGLRPPSQIKRSGLPRPSSIVRR", "length": 982, "header": "tr|Q9VUA5-1|Q9VUA5_DROME Isoform 1 of Short spindle 2, isoform C OS=Drosophila melanogaster OX=7227 GN=ssp2 PE=1 SV=1 CANONICAL=Q9VUA5-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 774, "start_aa": "Thr", "end_pos": 774, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr774", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, 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"https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUA5", "url": "https://www.uniprot.org/uniprotkb/Q9VUA5" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUA5", "url": "https://www.uniprot.org/uniprotkb/Q9VUA5" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VUA5", "url": "https://www.uniprot.org/uniprotkb/Q9VUA5" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VUA5", "url": "https://www.uniprot.org/uniprotkb/Q9VUA5" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VUA5", "url": "https://www.uniprot.org/uniprotkb/Q9VUA5" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUA5", "url": "https://www.uniprot.org/uniprotkb/Q9VUA5" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUA5", "url": "https://www.uniprot.org/uniprotkb/Q9VUA5" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": 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Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VUA6", "url": "https://www.uniprot.org/uniprotkb/Q9VUA6" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VUA6", "url": "https://www.uniprot.org/uniprotkb/Q9VUA6" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUA6", "url": "https://www.uniprot.org/uniprotkb/Q9VUA6" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUA6", "url": "https://www.uniprot.org/uniprotkb/Q9VUA6" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"https://flybase.org/reports/FBgn0061515", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "39554", "url": "https://www.ncbi.nlm.nih.gov/gene/39554", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VUB8", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VUB8*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR006760", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006760", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG6513", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG6513", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FLCVDEM", "url": "https://omabrowser.org/oma/group/FLCVDEM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VUB8", "url": "https://www.orthodb.org/?gene=Q9VUB8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10358", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10358", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10358:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10358:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04667", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04667", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-2465910", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-2465910", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001246745", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001246745", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VUB8", "url": "https://www.uniprot.org/uniprotkb/Q9VUB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VUB8-1", "url": "https://www.uniprot.org/uniprotkb/Q9VUB8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSAEENSNSPATTPQDTETTEQANLTDLEKIEEEKLKSKYPSGMRVPGGHSAFLQKRLQKGQKFFDSGDYQMAKQKGGGVKQVFANKVTTGEAIPTPETVPARKTSIIQPCNKFPATS", "length": 119, "header": "tr|Q9VUB8-1|Q9VUB8_DROME Isoform 1 of Endosulfine, isoform C OS=Drosophila melanogaster OX=7227 GN=endos PE=1 SV=1 CANONICAL=Q9VUB8-1" }, "isoforms": [ { "isoform_ac": "Q9VUB8-1", "url": "https://www.uniprot.org/uniprotkb/Q9VUB8/entry#Q9VUB8-1", "sequence": { "sequence": "MSSAEENSNSPATTPQDTETTEQANLTDLEKIEEEKLKSKYPSGMRVPGGHSAFLQKRLQKGQKFFDSGDYQMAKQKGGGVKQVFANKVTTGEAIPTPETVPARKTSIIQPCNKFPATS", "length": 119, "header": "tr|Q9VUB8-1|Q9VUB8_DROME Isoform 1 of Endosulfine, isoform C OS=Drosophila melanogaster OX=7227 GN=endos PE=1 SV=1 CANONICAL=Q9VUB8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VUB8", "url": "https://www.uniprot.org/uniprotkb/Q9VUB8" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VUB8", "url": "https://www.uniprot.org/uniprotkb/Q9VUB8" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUB8", "url": "https://www.uniprot.org/uniprotkb/Q9VUB8" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUB8", "url": "https://www.uniprot.org/uniprotkb/Q9VUB8" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VUB8", "url": "https://www.uniprot.org/uniprotkb/Q9VUB8" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VUB8", "url": "https://www.uniprot.org/uniprotkb/Q9VUB8" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VUB8", "url": "https://www.uniprot.org/uniprotkb/Q9VUB8" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUB8", "url": "https://www.uniprot.org/uniprotkb/Q9VUB8" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUB8", "url": "https://www.uniprot.org/uniprotkb/Q9VUB8" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VUB8", "url": "https://www.uniprot.org/uniprotkb/Q9VUB8" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VUB8", "url": "https://www.uniprot.org/uniprotkb/Q9VUB8" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], 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"https://www.ebi.ac.uk/intact/interactors/id:Q9VUC9*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR005203", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005203", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005204", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005204", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013788", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013788", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036697", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036697", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG8100", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG8100", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NACYARS", "url": "https://omabrowser.org/oma/group/NACYARS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VUC9", "url": "https://www.orthodb.org/?gene=Q9VUC9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11511", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11511", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11511:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11511:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03722", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03722", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03723", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03723", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001261825", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261825", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VUC9", "url": "https://www.uniprot.org/uniprotkb/Q9VUC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VUC9-1", "url": "https://www.uniprot.org/uniprotkb/Q9VUC9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRLTFVCLCFLVLQNRTESFGSPWKYFGSSNVEVNYNQRQDRQYFLLNLLIQVHKPLLHEELITMGSQLNDDPDSYKEGTWRYIKDFRERVHQNRVPGPFVILNQLDEEMPLNLLGIYRFLTMAVDWTSFQRNACFARIHFHPLLFVNALQMAVEEREDTKDLRMPAMYEVLPQLYFEKEVILTAQEVTWNQLSPIRLVTPKRRWIDILLGYRNPKQPWMEEEPIPTDPLIIDNARKVAYLSLDLELNSHWNSLITRLIISIEEGKEKTNEPIIIDGDRLVAFRGSFDEVNFKKHLALGSHFHNTKLYLYNLHQFVAALSMEDLATGQKSTELIYPPLMTTGGVPYKGTSLNIEAVRGIIDLTIDGLKDKIEMAVKHNNHAMDNLSIAGGIIGNNYLHICRQLNLAVNGQGINQPSMLGSATSNLRDPIYRSLLFRIYDLLKSYENENIFPDVGGRETPKIVDIQVSRLVTFEETMTTDLINLIDQQLLLSHRNNLQFLRRNLVARQHRLNHDPFSIGLDIVAPENLVVEARMYLSLPNQLRLRLHLDSFKCSLKRGLNHFERQFPTAISKPTLSELYEADYASTDVTTSNRFPPHLQLPRGTGDGLKLQLLVELSEWNGLESHFDGASVTVLAKTLKDVIIFHNQA", "length": 648, "header": "tr|Q9VUC9-1|Q9VUC9_DROME Isoform 1 of Fat-body protein 1 OS=Drosophila melanogaster OX=7227 GN=lincRNA.S5087 PE=4 SV=3 CANONICAL=Q9VUC9-1" }, "isoforms": [ { "isoform_ac": "Q9VUC9-1", "url": "https://www.uniprot.org/uniprotkb/Q9VUC9/entry#Q9VUC9-1", "sequence": { "sequence": "MLRLTFVCLCFLVLQNRTESFGSPWKYFGSSNVEVNYNQRQDRQYFLLNLLIQVHKPLLHEELITMGSQLNDDPDSYKEGTWRYIKDFRERVHQNRVPGPFVILNQLDEEMPLNLLGIYRFLTMAVDWTSFQRNACFARIHFHPLLFVNALQMAVEEREDTKDLRMPAMYEVLPQLYFEKEVILTAQEVTWNQLSPIRLVTPKRRWIDILLGYRNPKQPWMEEEPIPTDPLIIDNARKVAYLSLDLELNSHWNSLITRLIISIEEGKEKTNEPIIIDGDRLVAFRGSFDEVNFKKHLALGSHFHNTKLYLYNLHQFVAALSMEDLATGQKSTELIYPPLMTTGGVPYKGTSLNIEAVRGIIDLTIDGLKDKIEMAVKHNNHAMDNLSIAGGIIGNNYLHICRQLNLAVNGQGINQPSMLGSATSNLRDPIYRSLLFRIYDLLKSYENENIFPDVGGRETPKIVDIQVSRLVTFEETMTTDLINLIDQQLLLSHRNNLQFLRRNLVARQHRLNHDPFSIGLDIVAPENLVVEARMYLSLPNQLRLRLHLDSFKCSLKRGLNHFERQFPTAISKPTLSELYEADYASTDVTTSNRFPPHLQLPRGTGDGLKLQLLVELSEWNGLESHFDGASVTVLAKTLKDVIIFHNQA", "length": 648, "header": "tr|Q9VUC9-1|Q9VUC9_DROME Isoform 1 of Fat-body protein 1 OS=Drosophila melanogaster OX=7227 GN=lincRNA.S5087 PE=4 SV=3 CANONICAL=Q9VUC9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VUC9", "url": "https://www.uniprot.org/uniprotkb/Q9VUC9" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VUC9", "url": "https://www.uniprot.org/uniprotkb/Q9VUC9" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUC9", "url": "https://www.uniprot.org/uniprotkb/Q9VUC9" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUC9", "url": "https://www.uniprot.org/uniprotkb/Q9VUC9" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VUC9", "url": "https://www.uniprot.org/uniprotkb/Q9VUC9" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VUC9", "url": "https://www.uniprot.org/uniprotkb/Q9VUC9" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VUC9", "url": "https://www.uniprot.org/uniprotkb/Q9VUC9" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUC9", "url": "https://www.uniprot.org/uniprotkb/Q9VUC9" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUC9", "url": "https://www.uniprot.org/uniprotkb/Q9VUC9" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VUC9", "url": "https://www.uniprot.org/uniprotkb/Q9VUC9" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VUC9", "url": "https://www.uniprot.org/uniprotkb/Q9VUC9" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG8100", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG8100", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VUC9", "url": "https://www.uniprot.org/uniprotkb/Q9VUC9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "energy homeostasis", "id": "GO:0097009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097009", "evidence": [ { "database": "UniProtKB", "id": "Q9VUC9", "url": "https://www.uniprot.org/uniprotkb/Q9VUC9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "nutrient reservoir activity", "id": "GO:0045735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045735", "evidence": [ { "database": 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"https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, type 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, susceptibility to, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "HPC3", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, type 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, susceptibility to, 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "HPC4", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, type 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "HPC5", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, type 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "HPC6", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer, hereditary, 7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "HPC7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer, hereditary, 7", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, type 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "HPC9", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "prostate cancer, hereditary, 10", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "HPC10", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "prostate cancer, hereditary, 10", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, 12", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the EHBP1 gene." }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "EHBP1 familial prostate cancer", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "familial prostate cancer caused by mutation in EHBP1", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, 12", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, type 12", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "HPC12", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, 13", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the MSMB gene." }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "MSMB familial prostate cancer", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "familial prostate cancer caused by mutation in MSMB", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, 13", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, type 13", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "HPC13", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "HPC11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "HPC14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "prostate cancer, hereditary, 15", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "HPC15", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "prostate cancer, hereditary, 15", "description": "" }, { "id": "MONDO:0700275", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0700275", "name": "prostate cancer, hereditary", "description": "An instance of prostate cancer that is caused by an inherited genomic modification in an individual. Familial prostate cancer (FPC) is a malignant tumor of the prostate with an early onset. FPC is either asymptomatic or causes mictionary symptoms, erectile dysfunction, bone pain, venous compression and infectious or inflammatory syndrome (for the metastatic forms). It is also characterized by familial antecedents." }, { "id": "MIM:601518", "resource": "MIM", "url": "https://www.omim.org/entry/601518", "name": "Prostate cancer, hereditary, 1", "description": "Prostate cancer, hereditary, 1" }, { "id": "MIM:610997", "resource": "MIM", "url": "https://www.omim.org/entry/610997", "name": "Prostate cancer, hereditary, 9", "description": "Prostate cancer, hereditary, 9" }, { "id": "MIM:611868", "resource": "MIM", "url": "https://www.omim.org/entry/611868", "name": "Prostate cancer, hereditary, 12", "description": "Prostate cancer, hereditary, 12" }, { "id": "MIM:611928", "resource": "MIM", "url": "https://www.omim.org/entry/611928", "name": "Prostate cancer, hereditary, 13", "description": "Prostate cancer, hereditary, 13" }, { "id": "MIM:611955", "resource": "MIM", "url": "https://www.omim.org/entry/611955", "name": "Prostate cancer, hereditary, 11", "description": "Prostate cancer, hereditary, 11" }, { "id": "MIM:176807", "resource": "MIM", "url": "https://www.omim.org/entry/176807", "name": "Prostate cancer", "description": "Prostate cancer" } ], "unlinked_id_list": [], "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ] }, { "disease_id": "DOID:2841", "recommended_name": { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing." }, "synonyms": [ { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "bronchial hyperreactivity", "description": "" }, { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "chronic obstructive asthma", "description": "" }, { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "chronic obstructive asthma with acute exacerbation", "description": "" }, { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "chronic obstructive asthma with status asthmaticus", "description": "" }, { "id": "MONDO:0010940", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010940", "name": "inherited susceptibility to asthma", "description": "" }, { "id": "MONDO:0010940", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010940", "name": "asthma, nocturnal, susceptibility to", "description": "" }, { "id": "MIM:600807", "resource": "MIM", "url": "https://www.omim.org/entry/600807", "name": "Asthma", "description": "Asthma" } ], "unlinked_id_list": [ "DOID:0080811", "DOID:0080819" ], "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ] }, { "disease_id": "DOID:3068", "recommended_name": { "id": "DOID:3068", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3068", "name": "glioblastoma", "description": "A malignant astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derives_from multiple cell types including astrocytes and oligondroctyes." }, "synonyms": [ { "id": "DOID:3068", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3068", "name": "GBM", "description": "" }, { "id": "DOID:3068", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3068", "name": "adult glioblastoma multiforme", "description": "" }, { "id": "DOID:3068", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3068", "name": "grade IV adult Astrocytic tumor", "description": "" }, { "id": "DOID:3068", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3068", "name": "primary glioblastoma multiforme", "description": "" }, { "id": "DOID:3068", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3068", "name": "spongioblastoma multiforme", "description": "" }, { "id": "DOID:3068", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3068", "name": "glioblastoma multiforme", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "3068", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3068" } ] }, { "disease_id": "DOID:3069", "recommended_name": { "id": "DOID:3069", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3069", "name": "malignant astrocytoma", "description": "A malignant glioma that is has_material_basis_in astrocyte cells, a type of star-shaped glial cell, located in the brain and spinal cord." }, "synonyms": [ { "id": "DOID:3069", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3069", "name": "Astrocytic tumor", "description": "" }, { "id": "DOID:3069", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3069", "name": "astrocytoma of Cerebrum", "description": "" }, { "id": "DOID:3069", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3069", "name": "astrocytoma of brain", "description": "" }, { "id": "DOID:3069", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3069", "name": "astroglioma", "description": "" }, { "id": "DOID:3069", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3069", "name": "cerebral astrocytoma", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "3069", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3069" } ] }, { "disease_id": "DOID:3083", "recommended_name": { "id": "DOID:3083", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3083", "name": "chronic obstructive pulmonary disease", "description": "An obstructive lung disease that is a chronic and progressive disorder of small airways in the lungs and that is characterized by irreversible airflow obstruction, typically identified by reductions in quantitative spirometric indices, induced forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (less than 0.7 is diagnostic of COPD). Lung volume is increased and pulmonary hypertension may occur. The pathologic changes result in the disruption of the airflow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough and chest tightness. COPD is a consequence (an end result) of chronic bronchitis, emphysema or both." }, "synonyms": [ { "id": "DOID:3083", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3083", "name": "COLD", "description": "" }, { "id": "DOID:3083", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3083", "name": "COPD", "description": "" }, { "id": "DOID:3083", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3083", "name": "chronic obstructive airway disease", "description": "" }, { "id": "DOID:3083", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3083", "name": "chronic obstructive lung disease", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "chronic obstructive pulmonary disease", "description": "A chronic and progressive lung disorder characterized by the loss of elasticity of the bronchial tree and the air sacs, destruction of the air sacs wall, thickening of the bronchial wall, and mucous accumulation in the bronchial tree. The pathologic changes result in the disruption of the air flow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough, and chest tightness. The two main types of chronic obstructive pulmonary disease are chronic obstructive bronchitis and emphysema." }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "COLD", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "COPD", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "COPD, chronic obstructive pulmonary disease", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "chronic obstructive airways disease", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "chronic obstructive lung disease", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "chronic obstructive pulmonary disease (COPD)", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "chronic obstructive pulmonary disease, (COPD)", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "cold", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "cold (chronic obstructive lung disease)", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "disease (COPD), chronic obstructive", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "obstructive lung disease, chronic", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "obstructive pulmonary disease (COPD), chronic", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "pulmonary disease (COPD), chronic obstructive", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "3083", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3083" } ] }, { "disease_id": "DOID:3388", "recommended_name": { "id": "DOID:3388", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3388", "name": "periodontal disease", "description": "A mouth disease that is relating to or affecting the structures surrounding and supporting the teeth." }, "synonyms": [ { "id": "DOID:3388", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3388", "name": "disease of supporting structures of teeth", "description": "" }, { "id": "DOID:3388", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3388", "name": "periodontium disorder", "description": "" } ], "unlinked_id_list": [ "DOID:1483", "DOID:3086" ], "evidence": [ { "id": "3388", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3388" } ] }, { "disease_id": "DOID:4483", "recommended_name": { "id": "DOID:4483", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4483", "name": "rhinitis", "description": "A upper respiratory infectious disease which involves irritation and inflammation of the mucous membrane of the nose due to viruses, bacteria or irritants. The inflammation results in generation of excessive amounts of mucus leading to runny nose, as well as nasal congestion and post-nasal drip." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "4483", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4483" } ] }, { "disease_id": "DOID:5154", "recommended_name": { "id": "DOID:5154", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5154", "name": "borna disease", "description": "A viral infectious disease that results_in infection, which affects dopaminergic neurotransmission located_in central nervous system, has_material_basis_in Borna disease virus (Orthobornavirus bornaense), which is transmitted_by contact with infected oronasal secretions. The infection has_symptom mood disturbances, has_symptom behaviour disturbances, has_symptom cognitive disturbances, has_symptom neurologic disturbances, and has_symptom movement impairment." }, "synonyms": [ { "id": "DOID:5154", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5154", "name": "Enzootic encephalomyelitis", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "5154", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5154" } ] }, { "disease_id": "DOID:8544", "recommended_name": { "id": "DOID:8544", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8544", "name": "chronic fatigue syndrome", "description": "A syndrome that involves prolonged and severe tiredness or weariness that is unrelated to exertion, is not relieved by rest and for a minimum of six months and is not directly caused by other conditions." }, "synonyms": [ { "id": "DOID:8544", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8544", "name": "CFS", "description": "" }, { "id": "DOID:8544", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8544", "name": "Myalgic encephalitis", "description": "" }, { "id": "DOID:8544", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8544", "name": "Myalgic encephalomyelitis", "description": "" }, { "id": "DOID:8544", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8544", "name": "Postviral fatigue syndrome", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "8544", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8544" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VUE8", "url": "https://www.uniprot.org/uniprotkb/Q9VUE8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "bbg", "url": "https://www.uniprot.org/uniprotkb/Q9VUE8", "locus": { "chromosome": "3L", "start_pos": 14412828, "end_pos": 14536276, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0087007", "url": "https://www.ensemblgenomes.org/id/FBgn0087007" } ] } } ], "crossref": [ { "id": "FB:FBgn0087007", "url": "https://alliancegenome.org/gene/FB:FBgn0087007", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0087007", "url": "https://bgee.org/?page=gene&gene_id=FBgn0087007", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00136", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00136", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06762", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06762", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06763", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06763", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0087007", "url": "https://flybase.org/reports/FBgn0087007", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "39583", "url": "https://www.ncbi.nlm.nih.gov/gene/39583", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VUE7", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VUE7*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "Q9VUE8", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VUE8*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "DMTRIEC", "url": "https://omabrowser.org/oma/group/DMTRIEC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VUE7", "url": "https://www.orthodb.org/?gene=Q9VUE7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q9VUE8", "url": "https://www.orthodb.org/?gene=Q9VUE8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11324", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11324", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11324:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11324:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001246755", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001246755", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VUE7", "url": "https://www.uniprot.org/uniprotkb/Q9VUE7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VUE7-1", "url": "https://www.uniprot.org/uniprotkb/Q9VUE7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VUE8", "url": "https://www.uniprot.org/uniprotkb/Q9VUE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VUE8-1", "url": "https://www.uniprot.org/uniprotkb/Q9VUE8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASTPKANGTTAKTATINDDYITVVEVDDPTSNPKDRLKKLVKRQSSVAEDSSFITVLTINEMELLQQRKKEEDVGSGSSPTMEEQIENVTVFRLPGERLGFGLKFQGGTRSTELVQKLYIQSCAADSPASKVSTSWGNLREGDEIVSIDGRDVRELTRIDCVRGLKDNVAIKLVVRNGHGQKPPSEEDPQQQEHLSITLNAQPPPPPPVPPRKLVRRQNSKENQAQLLIEKPLTPPPDAEYYLNLLTESIKAGSESDDTASTISTVIDKFSVGSNYSSDSSLNGHELAKVLQPFTLLEQEFLPLEQPLGHPKLLIPGNNYENVEFKTEKVNVYENVELRSPETTPTPKPRVQLATVEPKKRSIIPMPRKIPTPTKLPIEVTPPRVPILEEPKTPTNNKVDSPKTPTNELKESPISATKIPKAKFSRAKTEGEIKLHLPAPKQQSPQSKSRIPIVSTPTAQKTVPKPVSPTMNGTPLSSNIPRLLQKQKSETDLKLNLYRSKSKESSPRPPLQRANSAEAPERTFIPVLLNGNSKSSNSLESVSSIGSSSSGNSVRSPKGPKPKPPERVQSLQKTQIPKLQALPTTPPQQIPKLSMQTFKQSPPTPRSTPVGTPSPTSNREIRFKIQTYESKTQDEDKLPSLFDLVHSQENDKDKDRDSDSLKTHNSITALLAAAAAEAADLSRESPPPLVVGKCMKIVDDTNTTTCYTSSSSGEEDEDDLDASNREYICEDGEKLGPPELINGPGPSEAYFNMFWHSNMLPTIGEVEEEFSSLEPQSLTNGNLVKSEESKKLPKMEVNAGGLAQLTDDKIADHDASATRADTRDEVTTNQTQEISSSSSSSVKSQKTTTTTRVTTTKTSSSSSSSSCSSTVIPDVAFKLQPYEERDDILSEPITTIHEERRVLSEQKTLSESRTRDALTGEEQLVTSANSKSSSARFKKISSNDNLLDLGDEQDMQEQPLTATITQESSLRERLECPQDNQSIDRGTLTLSERGKQLSEKEGLTTYTECETSEKESYLEGQQVLNGKGGFVSQDENSDQPTYEREVSETLTIVNDGEKQVTKKLEQNKEIAGKKGAKLLKKTDEERRLEQEAQKLIESYQKVKKEAEKLYKLELADDDQGFDLSAFEQAEEEDKPEVSEEIKEVKDSQPVKVDIQIEEEVKTPNQVIGEVKVEDVNKEIKETVQVSQQEIKKEVKVSHQETKETFKSEEKDESNELKIVKEEVKVTHQDLREQIQEIEAVKVVHKEVKVIKESAKVTTTTSHKQATKEVIISKEDHKNDSALPAVSTTKVEIISPPLEDDLGYVLHKHIIFPQEKVKTAPTPLPKPKPKPPVPTNKPKMPVNLTKPKSAPPPVPSKRSELSGSGGKPTPTQRRGSLETAQPPKPLERIIVGVEQRDEPEKPQPIINLASVDLPNVAPNSKQATVETTPVVEMPPDELQFESHQLPDDGEKEKDLHQESNDLLSGSSSSSVTTPITTPILVSATSSMDSVQSVIEVVNGMPIISNQQTDDDDIDEVAAYDDGMHLEAEGTKDVRPVQEVTTLTLDREHESDLGTLSNHHSNISSISGINASSNIPAATLISSSIKKTSTEAATTKPAAPQIPGKMELLSSNTGTTTTTTTATHHLHQATTTKQLLVQDYLSYASPPTYSRLPPDGHEFPPNFSEPLIMHSHPLKVTTELSYEIQKGGKDESSAPPLPKTGPPATVPRKVYRQDLVINVEPAPSLTRDYQRSLSGGTPRKPSDWRKDEKSEKSVRDKIAMFSSNNELDAIPPAPATAPISSSFTRKPLNRSSENLLDSCSSSSAPSLKTRAMSVENLNDVQRQYQLAKQLPQLHVADSMYSLNTATPTPSYASLPRRSHGGSYSSGVERRISFSGEGGDAANRKAAITNILEQRRRSLSKLRGLVIPERPQLLEPILDLPEIKSQVKAASGEDSTDSGLGESHRSTVNRNCQLGAGGAANNYRSILNTNQRRPLEQQLSQPPAKPPRTSLTPLQPRSMMIPPPPPPLDQESDTDSVFSHTARVATPPEKFALTRTLSSETNTSIASSNTSTLTSGSSAGSQASCSSLGSTPAVDLTRRVLKSQVINGEAVALSSRKSILASAKCRSAKSRGQEEDNDSTDGEACSLANRRMKPISSYKLQQQQIQLGKQLVVDKLINVAAYVELTSDTDDSSRRSDTPAKISAMFIDEERKASFKGDPNQQAKVKVEQVKPMVLPMLLPSAKREPLKQQTTAELREKFERSAAAQAQTQNHSPVIHKVTQKPHHERFSSLDSLASSSSGVSSTTQNVSTTQETATEFGSFSSLGSNQSLITAQDVQQIVEEADPPLKTPEAFIIVLQRENPESSIGITLAGGSDYEAKEITIHKILSNTPAAKDGRLKKGDRILAVNGMSMRGLTHRESISVLKTPRPEVVLVVTRSESLVVKALTKKRSSLGSLSSLNEKPTELDYERKRNYHKASRSLDLDLDLVSNEAGESPVATTPSTGSVSPPQPASLHDEDAEATIAGIRARRQLSRGDAAKLSTSELLERAAEARNAIAAEIRAQAEDAAASGGGARCVEIVKDSCGLGFSIEGGFDSPLGNRPLIVKKVFMGGAAQKTNQVRNGDEILSINGASTSRMTRVDAWNYMKQLPLGPVKICFA", "length": 2637, "header": "tr|Q9VUE8-1|Q9VUE8_DROME Isoform 1 of Big bang, isoform C OS=Drosophila melanogaster OX=7227 GN=bbg PE=4 SV=2 CANONICAL=Q9VUE8-1" }, "isoforms": [ { "isoform_ac": "Q9VUE7-1", "url": "https://www.uniprot.org/uniprotkb/Q9VUE8/entry#Q9VUE7-1", "sequence": { "sequence": "MLRINRYRDLGTLSNHHSNISSISGINASSNIPAATLISSSIKKTSTEAATTKPAAPQIPGKMELLSSNTGTTTTTTTATHHLHQATTTKQLLVQDYLSYASPPTYSRLPPDGHEFPPNFSEPLIMHSHPLKVTTELSYEIQKGGKDESSAPPLPKTGPPATVPRKVYRQDLVINVEPAPSLTRDYQRSLSGGTPRKPSDWRKDEKSEKSVRDKIAMFSSNNELDAIPPAPATAPISSSFTRKPLNRSSENLLDSCSSSSAPSLKTRAMSVENLNDVQRQYQLAKQLPQLHVADSMYSLNTATPTPSYASLPRRSHGGSYSSGVERRISFSGEGGDAANRKAAITNILEQRRRSLSKLRGLVIPERPQLLEPILDLPEIKSQVKAASGEDSTDSGLGESHRSTVNRNCQLGAGGAANNYRSILNTNQRRPLEQQLSQPPAKPPRTSLTPLQPRSMMIPPPPPPLDQESDTDSVFSHTARVATPPEKFALTRTLSSETNTSIASSNTSTLTSGSSAGSQASCSSLGSTPAVDLTRRVLKSQVINGEAVALSSRKSILASAKCRSAKSRGQEEDNDSTDGEACSLANRRMKPISSYKLQQQQIQLGKQLVVDKLINVAAYVELTSDTDDSSRRSDTPAKISAMFIDEERKASFKGDPNQQAKVKVEQVKPMVLPMLLPSAKREPLKQQTTAELREKFERSAAAQAQTQNHSPVIHKVTQKPHHERFSSLDSLASSSSGVSSTTQNVSTTQETATEFGSFSSLGSNQSLITAQDVQQIVEEADPPLKTPEAFIIVLQRENPESSIGITLAGGSDYEAKEITIHKILSNTPAAKDGRLKKGDRILAVNGMSMRGLTHRESISVLKTPRPEVVLVVTRSESLVVKALTKKRSSLGSLSSLNEKPTELDYERKRNYHKASRSLDLDLDLVSNEAGESPVATTPSTGSVSPPQPASLHDEDAEATIAGIRARRQLSRGDAAKLSTSELLERAAEARNAIAAEIRAQAEDAAASGGGARCVEIVKDSCGLGFSIEGGFDSPLGNRPLIVKKVFMGGAAQKTNQVRNGDEILSINGASTSRMTRVDAWNYMKQLPLGPVKICFA", "length": 1095, "header": "tr|Q9VUE7-1|Q9VUE8_DROME Computationally mapped isoform of Big bang, isoform C OS=Drosophila melanogaster OX=7227 GN=bbg PE=4 SV=2 CANONICAL=Q9VUE8-1" }, "locus": {} }, { "isoform_ac": "Q9VUE8-1", "url": "https://www.uniprot.org/uniprotkb/Q9VUE8/entry#Q9VUE8-1", "sequence": { "sequence": "MASTPKANGTTAKTATINDDYITVVEVDDPTSNPKDRLKKLVKRQSSVAEDSSFITVLTINEMELLQQRKKEEDVGSGSSPTMEEQIENVTVFRLPGERLGFGLKFQGGTRSTELVQKLYIQSCAADSPASKVSTSWGNLREGDEIVSIDGRDVRELTRIDCVRGLKDNVAIKLVVRNGHGQKPPSEEDPQQQEHLSITLNAQPPPPPPVPPRKLVRRQNSKENQAQLLIEKPLTPPPDAEYYLNLLTESIKAGSESDDTASTISTVIDKFSVGSNYSSDSSLNGHELAKVLQPFTLLEQEFLPLEQPLGHPKLLIPGNNYENVEFKTEKVNVYENVELRSPETTPTPKPRVQLATVEPKKRSIIPMPRKIPTPTKLPIEVTPPRVPILEEPKTPTNNKVDSPKTPTNELKESPISATKIPKAKFSRAKTEGEIKLHLPAPKQQSPQSKSRIPIVSTPTAQKTVPKPVSPTMNGTPLSSNIPRLLQKQKSETDLKLNLYRSKSKESSPRPPLQRANSAEAPERTFIPVLLNGNSKSSNSLESVSSIGSSSSGNSVRSPKGPKPKPPERVQSLQKTQIPKLQALPTTPPQQIPKLSMQTFKQSPPTPRSTPVGTPSPTSNREIRFKIQTYESKTQDEDKLPSLFDLVHSQENDKDKDRDSDSLKTHNSITALLAAAAAEAADLSRESPPPLVVGKCMKIVDDTNTTTCYTSSSSGEEDEDDLDASNREYICEDGEKLGPPELINGPGPSEAYFNMFWHSNMLPTIGEVEEEFSSLEPQSLTNGNLVKSEESKKLPKMEVNAGGLAQLTDDKIADHDASATRADTRDEVTTNQTQEISSSSSSSVKSQKTTTTTRVTTTKTSSSSSSSSCSSTVIPDVAFKLQPYEERDDILSEPITTIHEERRVLSEQKTLSESRTRDALTGEEQLVTSANSKSSSARFKKISSNDNLLDLGDEQDMQEQPLTATITQESSLRERLECPQDNQSIDRGTLTLSERGKQLSEKEGLTTYTECETSEKESYLEGQQVLNGKGGFVSQDENSDQPTYEREVSETLTIVNDGEKQVTKKLEQNKEIAGKKGAKLLKKTDEERRLEQEAQKLIESYQKVKKEAEKLYKLELADDDQGFDLSAFEQAEEEDKPEVSEEIKEVKDSQPVKVDIQIEEEVKTPNQVIGEVKVEDVNKEIKETVQVSQQEIKKEVKVSHQETKETFKSEEKDESNELKIVKEEVKVTHQDLREQIQEIEAVKVVHKEVKVIKESAKVTTTTSHKQATKEVIISKEDHKNDSALPAVSTTKVEIISPPLEDDLGYVLHKHIIFPQEKVKTAPTPLPKPKPKPPVPTNKPKMPVNLTKPKSAPPPVPSKRSELSGSGGKPTPTQRRGSLETAQPPKPLERIIVGVEQRDEPEKPQPIINLASVDLPNVAPNSKQATVETTPVVEMPPDELQFESHQLPDDGEKEKDLHQESNDLLSGSSSSSVTTPITTPILVSATSSMDSVQSVIEVVNGMPIISNQQTDDDDIDEVAAYDDGMHLEAEGTKDVRPVQEVTTLTLDREHESDLGTLSNHHSNISSISGINASSNIPAATLISSSIKKTSTEAATTKPAAPQIPGKMELLSSNTGTTTTTTTATHHLHQATTTKQLLVQDYLSYASPPTYSRLPPDGHEFPPNFSEPLIMHSHPLKVTTELSYEIQKGGKDESSAPPLPKTGPPATVPRKVYRQDLVINVEPAPSLTRDYQRSLSGGTPRKPSDWRKDEKSEKSVRDKIAMFSSNNELDAIPPAPATAPISSSFTRKPLNRSSENLLDSCSSSSAPSLKTRAMSVENLNDVQRQYQLAKQLPQLHVADSMYSLNTATPTPSYASLPRRSHGGSYSSGVERRISFSGEGGDAANRKAAITNILEQRRRSLSKLRGLVIPERPQLLEPILDLPEIKSQVKAASGEDSTDSGLGESHRSTVNRNCQLGAGGAANNYRSILNTNQRRPLEQQLSQPPAKPPRTSLTPLQPRSMMIPPPPPPLDQESDTDSVFSHTARVATPPEKFALTRTLSSETNTSIASSNTSTLTSGSSAGSQASCSSLGSTPAVDLTRRVLKSQVINGEAVALSSRKSILASAKCRSAKSRGQEEDNDSTDGEACSLANRRMKPISSYKLQQQQIQLGKQLVVDKLINVAAYVELTSDTDDSSRRSDTPAKISAMFIDEERKASFKGDPNQQAKVKVEQVKPMVLPMLLPSAKREPLKQQTTAELREKFERSAAAQAQTQNHSPVIHKVTQKPHHERFSSLDSLASSSSGVSSTTQNVSTTQETATEFGSFSSLGSNQSLITAQDVQQIVEEADPPLKTPEAFIIVLQRENPESSIGITLAGGSDYEAKEITIHKILSNTPAAKDGRLKKGDRILAVNGMSMRGLTHRESISVLKTPRPEVVLVVTRSESLVVKALTKKRSSLGSLSSLNEKPTELDYERKRNYHKASRSLDLDLDLVSNEAGESPVATTPSTGSVSPPQPASLHDEDAEATIAGIRARRQLSRGDAAKLSTSELLERAAEARNAIAAEIRAQAEDAAASGGGARCVEIVKDSCGLGFSIEGGFDSPLGNRPLIVKKVFMGGAAQKTNQVRNGDEILSINGASTSRMTRVDAWNYMKQLPLGPVKICFA", "length": 2637, "header": "tr|Q9VUE8-1|Q9VUE8_DROME Isoform 1 of Big bang, isoform C OS=Drosophila melanogaster OX=7227 GN=bbg PE=4 SV=2 CANONICAL=Q9VUE8-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1369, "start_aa": "Thr", "end_pos": 1369, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1369", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1847, "start_aa": "Thr", "end_pos": 1847, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1847", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VUE7", "url": "https://www.uniprot.org/uniprotkb/Q9VUE7" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VUE7", "url": "https://www.uniprot.org/uniprotkb/Q9VUE7" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUE7", "url": "https://www.uniprot.org/uniprotkb/Q9VUE7" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUE7", "url": "https://www.uniprot.org/uniprotkb/Q9VUE7" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VUE7", "url": "https://www.uniprot.org/uniprotkb/Q9VUE7" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VUE7", "url": "https://www.uniprot.org/uniprotkb/Q9VUE7" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VUE7", "url": "https://www.uniprot.org/uniprotkb/Q9VUE7" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUE7", "url": "https://www.uniprot.org/uniprotkb/Q9VUE7" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUE7", "url": "https://www.uniprot.org/uniprotkb/Q9VUE7" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VUE7", "url": "https://www.uniprot.org/uniprotkb/Q9VUE7" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VUE7", "url": "https://www.uniprot.org/uniprotkb/Q9VUE7" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AF93-1", "protein_name": "Pro-interleukin-16", "gene_name": "Il16", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLAPWGQKCICKGQVQQLGCGCPVLPAGGGHHQYALWHIHRRTPLLGCQGTAPPPCCSWHLLPGQANRTHAAAAKPSSSTTHRPRPGEQERKKRGLTSSLRMEPHSHSGKSRKSTKFRSISRSLILCNAKTSDDSSSPDEKYPDPFETSLCQDKEGFFHSSMQLADTSEAGLSNIPDLALASEAAQLQAAGSDRGKHCRKMFFLKESSTTSSKEKAGKSEAQSSNFLFPKACHQRTRSNSTSVNPYSAREMDFPMTKKSAAPTDRQPYSLCSNRKSLSQQLDYPVSGTARPTRSLSTAQLGQLSGGLQASVISNIVLMKGQAKGLGFSIVGGKDSIYGPIGIYVKSIFAGGAAAADGRLQEGDEILELNGESIAGLTHQDALQKFKQAKKGLLTLTVRTRLTTPPSLCSHLSPPLCRSLSSSTCGAQDSSPFSLESPASPASTAKPNYRIMVEVSLKKEAGVGLGIGLCSIPYFQCISGVFIHTLSPGSVAHLDGRLRCGDEIVEINDSPVHCMTLNEVYTILSHCDPGPVPIIVSRHPDPQVSEQQLKEAVAQAVEGVKFGKERHQWSLEGVKRLESSWHGRPTLEKEREKHSAPPHRRAQKIMVRSSSDSSYMSGSPGGSPCSAGAELQPSEGEGSTHSPSLPPGEEQEPCPGVPSRPHQESPPLSESLERDSHPPLKLKNSFEILVRKPTSTKPKPPPRKYFKNDSEPQKKLEEKEKVTDPSGHTLPTCSQETRELLPLLLQEDTAGRTLCTAACCPGPAASTQTSSSTEGEPRRSASPETPASPGKHPLLKRQARMDYSFDSTTEDPWVRISDCIKNLFSPIMSENHSHMPLQPNASLGEEDGTQGHPEGGLSKMDTANGAPRIFKSADGSTVKKGPPVAPKPAWFRQSLKGLRNRVPETRRAPEVASAIQTTPVSRDASGPQSQASSSSIRQRISSFENFGSSQLPDRGVQRLSLQPTSGETTRLPGKQDEGRFSGLPAQGTKVTAKHRQTEVEPPSTTFPNSSEVGDPDMSESPPPGQRPNPKALSPDPLLRLLTTQTEDTQGPGFKMPSQRARSFPLTRTQSYETKLLDEKSSKLYSISSQLSSAVMKSLLCLPSSASCGQITCIPKERVSPKSPCNNSAAAEGFGEAVASDTGFSLNLSELREYSEGLTEPGETEDRNHCSSQAGQSVISLLSAEELKKLIEEVRVLDEATLKQLDSIHVTVLHKEEGAGLGFSLAGGADLENKVITVHRVFPNGLASQEGTIQKGNEVLSINGKSLKGATHNDALAILRQARDPRQAVIVTRKAIVEAAHDLNSSTDSAASASVASGISVESVEATVCTVTLEKTSAGLGFSLEGGKGSLHGDKPLTINRIFKGTEQGDAVQPGDEILQLAGTAVQGLTRFEAWNVIKALPDGPVTVVIRRNGLEGKQTTASADL", "length": 1425 }, "evidence": [ { "id": "RGD:1583872", "url": "https://alliancegenome.org/gene/RGD:1583872#orthology", "database": "AGR" }, { "id": "HGNC:5980", "url": "https://alliancegenome.org/gene/HGNC:5980#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-130103-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130103-3#orthology", "database": "AGR" }, { "id": "MGI:1270855", "url": "https://alliancegenome.org/gene/MGI:1270855#orthology", "database": "AGR" }, { "id": "FB:FBgn0087007", "url": "https://alliancegenome.org/gene/FB:FBgn0087007#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M2BH19-1", "protein_name": "Uncharacterized protein si:dkey-92i15.4", "gene_name": "si:dkey-92i15.4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSLHTGTSVCQFPEADTTGSVTEGTQTSDGTAAQSQNQSSVKPYGSAAARFKIRSAKTLTTKDLRKKSFSFERGNVEDSSQKSHPSKDLNKACTSASYTHTNIDETGKTLSKDVRMDSTPLISSEKSRASDKSLITQEDKTQTASDRNRGDELRKFHQLSKSKSLDWRVMNSRAGLGNTTVMTSGTRDYSHYMRRSDSSEKAETNNNVTSSTQENQPITYSRRIQANNVANDVDQSSDRKVSPVSGYTSLRMNQISFAIEKASSGQSLPSRLKPRLSLDSIKDGGSLWAQQPGESSLGQADKKIGFWTKEQGLSNAEEVTGNQTIKERIDKLLASHGKPDDLSPDISFTKSMDTVDSTPSQGKNTTDSSDYTQSQQNKPLDNAEKAGTFPRRFSKTYFGPKPEPSLNNENRNVQRENPSGLSSSLSSKPKWSTESYKNAQSLLHNNNEESSKRAFTGSPNYCSQSLERTRSKLSATGQYNIHRNQSAYSDSSSNTSSKDLNCLSSRIKEDILKDKQSDKETTKGLDIKENKCHGGSQVETTQPKNQLSSKEAAHSEIHKEGKDNVFTFKTEGKRGEGVLEKFRAQSLDSVKNTISMFESLAQQGTPKDLYSKRTLSVPEHPKPAALVRKSGSERNLHFGRSVGNRENPGTNVFNKNEPNKQTEEGTLNLSKAPHSNSSVKVTPTFEPRQEAYRKSVELVPEFKQMNELRTDRVSRKDDESRTAGQNHIDEPDSALTVHSRLRKMRAMEEKVENPEFSQHSKRLVKQQTIHVKTEDDGDDEDEDTPINSPISAPNTISIEKQSYIGFITVNGTHPKVLPNQPQSSSHFQTAHSSLNHSNNNNYKIREDLTSLTTTGMARWSSDEEDYDEETDTEEDSDSGESSVTITSNMSQSERRSFSVSLMDLCNFGGVDYNSPEWLEDHEDLPSSRSASLSSDISVFSSVTLLSTDELDRLLDDVKSLGDDTLKKYEDVQVVVLHKEVGSGLGFTLAGGVDQNKPVTVHRIISGGVAAQEGSIFEGAQVLSINGTALQNSAHWEALRTLRKAKGQGMAVVVLQSGNSRKDVTEKAGITGRRVRVTLNKSSSDLGFSLEGGVGSSSGDKPLTIQKIFRGGPMSEVFPGDELLEVQGQSLKGLMRLEAWNLIKKLPSGPVDILLHRPHQPH", "length": 1161 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-030131-8422", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-8422#orthology", "database": "AGR" }, { "id": "FB:FBgn0087007", "url": "https://alliancegenome.org/gene/FB:FBgn0087007#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3AZV3-1", "protein_name": "PDZ domain-containing protein 2 isoform X1", "gene_name": "pdzd2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPITQENALSHLLLLENWLRAREEDRDEGDVLRMSTVCKPAIRKLVEYIQLNFTEVESPLYSINPLREEIDAEVKAVCLNKSEEDGPEFGLSFGNIPIFGDPEGKKKGVRRRRRKGDKGPVLDVGCIWVTEVKKNSPAARCGDIKLRDELLSLNGQLMVGVDVTGASYLADQCWNGGCIYLIMLRRIKRKAPLPPCNGSNGGNFVDVSNDHRRSVSSETAGSPTHNGQNGKRTRKFGVISRSSFTRDSKDSKDSRDCELENGYSSMEAEVTSPESSSPQDTPTNDSPITGPSELMMSNHMRVGSTATLPCRSRSRMSENFKTESISSEPSGQPREGGRIWKMHMVKGQDGLGIQITGGRGSKRSPHGIIVAHVEEGGATQRDGRLKAGDELLMINGHSLVGLSHQEAVAILRSTAGLVQLVVASRDESEVDFHKYPSTSLPDLVSTCSGPDASPSPGEEKENMEPDMEDVRASSLSLPTQDLFTDHDRLDERGRIEGPKGCCRSPTPMKFRSRSQGGGSRLESVGEDDELIVENGDTGSDVAEKPTRGGRKHSLPQQLDTVGIRQEYQIVKKSARSLSTVQVESPWRLAQPSIISNIVLMKGQGKGLGFSIVGGQDSARGRMGIFVKTIFPNGAAAADGRLKEGDEILEVNGESLQGLTHQQAIQTFKQLKKGVVTLTVRTRLRSPSLTPCPTPTLLSRSSSPNSNASGGTPVPQSFDEGDSRKGPGPKDRIIMEVTLNKEPGVGLGIGACCLTLENSAPGIYIHSLAPGSVAKMDGRLSRGDQLLEVDSVSLRHAALSEAYAILSECGPGPVSLIISRHPNPKVSEQEMDEVITRSTHRDSHSSHTLGLPSKSPSPTVKVKQGEGNPALSWTMKRFLEPASRQGSLSSEAELSQYFSVHDVPSQSSLSETMAMGSSDDDMLHSSRSCNTSMEESAAPQPHVYRDGSYRGSGSSPTTPECCKASGGTGRTAETAQQASVGSSPSSVRSPLLRQRRVICYEDEPSDDETGLEDDNGPFRRLLRGVSDGHQHQEEDSGIVIATSSLEVDDESQDGSESHRQISSEPTTPFYGSSIESEEGTTGLSSAESPFMPIHCVEATNLGVKKEPHREGQEVKRSPKLEHKAVTRVKSMMSIECPNPPQRTKGEDPALFPANPAQVTQNCTRPPCRMMHCKKGESSELAGVCTIETIVLQRGETESFGLDLEIKSAPLKVLVTGLRPGGVAEREASGKMSFGDEIVTIGDTPVCTSSYQEICDLMHNLPITLTLEIKKPVSAVDRLSSLIMSSGCESSSKLEASRASPEERNHTDTTQIPSSENANAKQAVTTHSMPVTNIDDVVSELNSAESEVKDQSAEEYSKEDDRGTGAPSQPNPLDFSALDMGNGTCHFPLGKTFLNSYSRNFSNLGESIVPLQKGDGHKPSMYSMVDSDSESDSTDSAVKIEKSQGHSEGPRDTDTDEEEVELCFSTVSQSAFSQSEGSSLPDGNGCATRQSVDQPGAKLLTSTDLHKPSSVSAQDRDPQDPICHEDSGKDLLNGKNGHAKTTQSNCSDDEKCETMSKSFQTCQTPTDTPVTQNNCHVTPRSQDRTARLLSEASRSAEKLNTGQAPLKLTVSEPNASHYANGKSSGQASLALASKEKEKVLSTLDLKSTFSQNQSKSATSVRSLGTKSSNDSPVSPLLRGRLKVDDKKSNTSSKLKGLSIKSKCKDQEQPVSRSPRAESPVQRKSLVSPSQSPKLHSKRTTPTGSPKSTRSSEKSRVSCCKTDQNQLTVSTNSKVNPINTAKEELKQLKKEDALDLKQQVSKPEVTVGNTQRTFIEVRLSSSSSSTPVLPRKEVVNASHLSLASLSVDSIKWKESNSDFSLGSHTIPLESINSSSSSAQQNGDNKANETAEKVFCNGQEESLLRKSTNKDAASNLKTSKSKLYLRGLDRRSCSTDAGGSLDTNPFSVRQRIQSFESLASFDRSVIKCIDIPFYAVNSKPTLNRRLSGYAGSVSSQSIDSRSLRRSFSSCVDNLSSTPSLQNWSTSSTATNCESTPSNQTTETVMKEMKNETSQNQPTVHTPPVLRSRNARAHGGLSRSKLREIKALSMPELDKLCTEDFTSDPGNVIFKTELEINPRRSIDPSSQCTVVTRVSSVDLGALGSTSNGEHHEIQDTGLSCWSISLKDLEFSPLDQNKVNDVLCSLPTKVDVTSLIQEANATSEVKDDVYFVILTKEQGAGLGFSIAGGVDLEQKSITVHRVFTRGVAGVEGTIHRGDRILSINGTSLSRITHGEALSCLHQTRLPKQALVIIQKDKNAEPTSPRQELSLQTAVCTSPGPRENIRGHKTSVEVGPDGALSVELQKTTAGLGFSLDGGKASAHGDRPLYIKRIFRGGAAEQSRVIDVGDELLAINGRSLQGLMHYDAWNIIKSVSEGPVQLVIRKPRTSV", "length": 2423 }, "evidence": [ { "id": "HGNC:18486", "url": "https://alliancegenome.org/gene/HGNC:18486#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060526-297", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-297#orthology", "database": "AGR" }, { "id": "MGI:1922394", "url": "https://alliancegenome.org/gene/MGI:1922394#orthology", "database": "AGR" }, { "id": "RGD:619958", "url": "https://alliancegenome.org/gene/RGD:619958#orthology", "database": "AGR" }, { "id": "FB:FBgn0087007", "url": "https://alliancegenome.org/gene/FB:FBgn0087007#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9QCG1-1", "protein_name": "Pro-interleukin-16", "gene_name": "il16", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLSFERPPPLAAMHAGREPPSVAIQPLRNTHPQRRRTKRMERGKAGLSSKKLAVLSRSLLICSSSAHEDASSPEEKYREPWDVPLEDRRPDGTLMSRSVSVQTSYRGHEGPKRAMRRSFSIKETSFWRMCVATRDDALHTADRKLQNCDNEASVAQDLHRETYIYFGERLAPFNGQVINEQPNPEPDLHKHKTTESRNTSSKAFTENRALFTNTTESQQLGYGYGEKEPMGNNNNLQMPSIKVSDDDVKNIDNEDQGCQEMSCKRSRSNSTSVHPYWIGDLETIIMKTPELFPCSAHNTAAFYGNRKSLSQQLEFPHSVPQAVVRPSRSLSSAHLVPSCSSVQAFIISNIVLMKGHGKGLGFSIVGGRDSMYGPMGIYVKTIFPGGAAAADGRLQEGDEILELNGESLHGLTHEDALHKFKQVKKGLLTLVVRTSLRVGAVMGSHGQASQLCRSRSLSSSTAISRVSADLGEYNCLNNPAKAQDRVMMEITLHKEFGVGLGIGLCCVPSSGGCPGIYIHTLSPGSVAHMDGRLRCGDEIMEINETVVCNMTLNDVYTVLSQCSPGPVHIIISRHPDPKVSEQQLNEAISQAVENSRLRKDRSQWSMDGCNSSLRRPESCCHSRQKCMRCVDRSTSQLTCRRTQKPMIRSCSEGAYSQRCCIPNSTTAQSFLHTDHVSLTTNSETSLNNTLSQSSFTDDDYNIPYKCPVNFNGKQTFDVNASSGLVNQPRKYYRQQQEVSSQEALNVSSGSSRDSPVKEEDLMLSQSNCQFFCSLYRALRKISRLLFKNEVVEHAELGTKASACISEPKSDSTHRGDRLHKDPECSSQVCGSSKRVGLRRQAHLEVSTDQPLDPWVKLTDSPENQSYCSKTMSDHNGDSEVNGTASETTESKSEQATSVKKGPPVAPKSARARQSMKSIRSGKPITEALRNQQDNRSHETGRTFGISSRAASSGGNLSIRQKISSFETFSSPDGSERPSWRMAPTASVPPTEKTTKTSSADYSNADRTRVNTSNLRNNDYCQSTPPISATTLPSEEHSTSLILESHPEVEKQSTSHDSETCKSIPVEEPTVDPTEEITTAVETEQELVSSAKSSVDTEHEPVSSAETEQEPVSSTKSSVETEPVTSAETKQEPVSSEKDLPSVTHVPRRSSSSKEAPGEKAEEAGTHAVSLRTRSLPLSPSSDGPISSGLEGESLGIILSFSNQVSSALMRSMQSLPQSPCIRLGNPWSAPPGSPLHNPIEEDSAAENPHASTALENNEKGFSVSLAELRERTIERGEECKTDDWKPEQALTSASAACAQSMLSVLPQPEIQRMIQEVKDLDEDTLRQLEDIHVVILHKEEGAGLGFSIAGGIDLENKATTVHRVFPSGLAAQEGTIEKGDEVLSINGQTLKNVTHSDATAILRQSRTLKQAVVVVSKNKDAEGKSANANESSCSGGAESSIAGDDGGEVVTFELEKNAGGVGFSLEGGKGSISGDRPLAVNRIFTGSDAEQKGLKSGDEVLQIQDSSLQGLTRFEAWTLIKNLNDGPFTLIVKRRRCEQS", "length": 1540 }, "evidence": [ { "id": "RGD:1583872", "url": "https://alliancegenome.org/gene/RGD:1583872#orthology", "database": "AGR" }, { "id": "HGNC:5980", "url": "https://alliancegenome.org/gene/HGNC:5980#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-130103-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130103-3#orthology", "database": "AGR" }, { "id": "MGI:1270855", "url": "https://alliancegenome.org/gene/MGI:1270855#orthology", "database": "AGR" }, { "id": "FB:FBgn0087007", "url": "https://alliancegenome.org/gene/FB:FBgn0087007#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9Q1M1-1", "protein_name": "PDZ domain-containing protein 2", "gene_name": "Pdzd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPITQDNALLHLPLLYEWLQNSLREGGDSPEQRLCQAAIQKLQEYIQLNLAVEENTVPPEHSPPEMEICTVYLTKQLGDTETVGLSFGNIPVFGDYGEKRRGGKKRKTHQGPVLDVGCIWVTELRKNSPAGKSGKVRLRDEILSLNGQLMVGVDVSGASYLAEQCWNGGFIYLIMLRRFKQKAHLTYNGNSGNSSEPGETPTLELGDQTSKKGKRTRKFGVISRPAIIKAPEDSKSNSGCDTADDPSSELENGTDSELGNGHAFELENGPNSLKDVAGPHLERSEADREAELRVPKTEAPLSDSNDKRRFSKTGKTNFQSSDSLAREEVGRIWKMELLKESDGLGIQVSGGRGSKRSPHAIVVTQVKEGGAAHRDGRLSLGDELLVINGHLLVGLSHEEAVAILRSATGMVQLVVASKESSAEDLLKLTSKSLPDLTSSVEDISSWTDNEDQEAARDDEEGTGSAAVRGTMLGSEESQDVGSSEESKGNNLESPKQGNSKMKLKSRLSGGVHRLESVEEYNELMVRNGDPRIRMLEVSRDGRKHSLPQLLDSTGTSQEYHIVKKSTRSLSTTHVESPWRLIRPSVISIIGLYKEKGKGLGFSIAGGRDCVRGQMGIFVKTIFPNGSAAEDGRLKEGDEILDVNGIPIKGLTFQEAIHTFKQIRSGLFVLTVRTKLLSPSLTPCSTPTHMSRSSSPSFNSSGGAPAGGGQDEGGSASLGRKAPGPKDRIVMEVTLNKEPRVGLGIGACCLALENSPPGIYIHSLAPGSVAKMESNLSRGDQILEVNSVNVRHAALSKVHAILSKCPPGPVRLVIGRHPNPKVSEQEMDEVIARSTYQESKEANSSPSLGTPLKSPSLAKKDSLLSESELSQYFVHDGQGSLSDFVVAGSEDEDHPGSGYETSEDGSLLTVPSAYRETGKARANSLVTLGSQRGSGLLHKQVTVARQASLPGSPQVLRNPLLRQRRVRCYDSNDGSDDEDFDGEGDCVSLPGVLPGPGRPLVQDDTRFALATSSKSIDVNKQDERLQKPLVSKACSVPLLGSSLDSEHSIHGGTAGTPPKAASLPGSVETPKNGPGGSRRKEMSGSRSSPKLEYRVPADTQSPRSPENGTSPPQKTENLVSRHKPVARISPHYKRSDAEEAPSETANGPCAQDLKVQASSVKDPVAGHQPGGTAEKELRGNPTPGDSSVPTNCGPASTPCHPNTGLPTENPQGAAPECGPHPGTGWDGSSDHPPSPGKSREVRPDSSETPAVTEQVLQPESLSQPVSPGTSEPESQGVSKMKPASQRSLSPREKASALPDSSRTWAGPGDSTPSTRRAAVPMSIGETRATAIPHPSLLGQERSRDPSGPSKALETPGHCVPTSLKDRALLEETASASGKLSHAGPSVPVTTDGTLSGSTESPVTDIDKFIGEAPEAWLSQSPQRADCRTHQDIFESQPPGGAGGGSSHHGKTGGTGSPPPPQWTFQPSVLDSVHPDKQLAGNKNFLNNYSRNFSSFHEDGVSEPSPSSMYGDAEDSSSDPESLVEDPRAAARNNWPAPPSHESSRKEGSSESEDEQIEICAPGGCPETPVPAQAPAQAAGGAVPSVQQTVREPVGDACEKACFMTGASNTCIPGSSQPFSFLDVSSLEHETWAGVQTSRSHMPGCAEETLAVSSTGSVVGDSQPSQTTRPCGNPPFVLRNPDMVNGLGQDLLDEGTPDKGADASHVMSSVYALGAEGPKNGEAVLANLHIAKGGNLDGLLQKPKTTSRRPIMTWFKDINKDSQGAHLQSKSEKEQPSMLAMSPGSKGNTVNPSHRKGMAVPKSPPPRQKSQENKDLSPKSPVETLSNCQKPKGSPKLKRLNSKSKASPEAPVASPAKGGRTDHRKSLPSPQAAHKMLSKAVSHRLHIADQEEPKNTAGDTSKPPQCVPESKPPLAASGSLRTSASDTSIRTITSPLTSPKPLPEQGANNRFHMAVYLESDTSCPATSRPPRYGPEGKVPHANSGSVSPSASRTNIALAGVRQSKQFTHSRVDLVLTEAAQPQGISEKGTEKMASDPLERTNQLKIIEISSERMPKNACGDKPPGSDRKGGFLTQSNCQEKSSVRLRQSAESSPKQPHFPPSQASQGEQEMRWSYSMARLASSSPSAPQLPSKMPDYSQGKSSQMPASVGVPKNGVPVGLAGEEPPYFTPRPATRTYSMPAQFSSHFGREGLSPPSPSHSPQDPQVTAMSGSLSEKSAKGVTNEQGVYSVKPLLETLRNPPPVDVGDVSAVPEASGLIPDKLKVTRRHYYCEQSWPHESTSFFSVKQRIKSFENLANSDRPAAKSATSPFLSVSSKPPVNRRSSGSITSGRPSDGTARSLRRSLSSCSENQSEASSLLPQMTKSPSSVTLTVSRQNPPETNNKGHSPDPKKSLVPVGIPISTGSPASPIKRNKSSVRHAQPSPVSRSKLQELRALSMPDLDKLCSGEDYSASPGAVLFRTQLEITPRRSQGSPATSPASSPARGHADVNGSAFLSCPVNGGNRVYPKGNSSPTVPTGSREWGESLRAMPSGKSWSVNLDQLLASVGYQQRLQAVLSLVGSKSPILPLIQEAKAQSENKEDICFIVLNKKEGSGLGFSVAGGADVEPESVLVHRVFSQGVASQEGTVSQGDFLLSVNGTSLAGLSHSEVTKVLHQAELHKHVLMIIKKGNDQPRPSFRQEPPSANGKAPFPRRTLPLEPGAGRNGAAHDALCVEVLKTSAGLGLSLDGGKSSIAGDGPLVIKRVYQGGAAEQAGTIEAGDEILAINGKPLVGLVHFDAWNIMKSVPEGPVQLVIRKHRDS", "length": 2796 }, "evidence": [ { "id": "HGNC:18486", "url": "https://alliancegenome.org/gene/HGNC:18486#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060526-297", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-297#orthology", "database": "AGR" }, { "id": "MGI:1922394", "url": "https://alliancegenome.org/gene/MGI:1922394#orthology", "database": "AGR" }, { "id": "RGD:619958", "url": "https://alliancegenome.org/gene/RGD:619958#orthology", "database": "AGR" }, { "id": "FB:FBgn0087007", "url": "https://alliancegenome.org/gene/FB:FBgn0087007#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O15018-1", "protein_name": "PDZ domain-containing protein 2", "gene_name": "PDZD2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPITQDNAVLHLPLLYQWLQNSLQEGGDGPEQRLCQAAIQKLQEYIQLNFAVDESTVPPDHSPPEMEICTVYLTKELGDTETVGLSFGNIPVFGDYGEKRRGGKKRKTHQGPVLDVGCIWVTELRKNSPAGKSGKVRLRDEILSLNGQLMVGVDVSGASYLAEQCWNGGFIYLIMLRRFKHKAHSTYNGNSSNSSEPGETPTLELGDRTAKKGKRTRKFGVISRPPANKAPEESKGSAGCEVSSDPSTELENGPDPELGNGHVFQLENGPDSLKEVAGPHLERSEVDRGTEHRIPKTDAPLTTSNDKRRFSKGGKTDFQSSDCLAREEVGRIWKMELLKESDGLGIQVSGGRGSKRSPHAIVVTQVKEGGAAHRDGRLSLGDELLVINGHLLVGLSHEEAVAILRSATGMVQLVVASKENSAEDLLRLTSKSLPDLTSSVEDVSSWTDNEDQEADGEEDEGTSSSVQRAMPGTDEPQDVCGAEESKGNLESPKQGSNKIKLKSRLSGGVHRLESVEEYNELMVRNGDPRIRMLEVSRDGRKHSLPQLLDSSSASQEYHIVKKSTRSLSTTQVESPWRLIRPSVISIIGLYKEKGKGLGFSIAGGRDCIRGQMGIFVKTIFPNGSAAEDGRLKEGDEILDVNGIPIKGLTFQEAIHTFKQIRSGLFVLTVRTKLVSPSLTPCSTPTHMSRSASPNFNTSGGASAGGSDEGSSSSLGRKTPGPKDRIVMEVTLNKEPRVGLGIGACCLALENSPPGIYIHSLAPGSVAKMESNLSRGDQILEVNSVNVRHAALSKVHAILSKCPPGPVRLVIGRHPNPKVSEQEMDEVIARSTYQESKEANSSPGLGTPLKSPSLAKKDSLISESELSQYFAHDVPGPLSDFMVAGSEDEDHPGSGCSTSEEGSLPPSTSTHKEPGKPRANSLVTLGSHRASGLFHKQVTVARQASLPGSPQALRNPLLRQRKVGCYDANDASDEEEFDREGDCISLPGALPGPIRPLSEDDPRRVSISSSKGMDVHNQEERPRKTLVSKAISAPLLGSSVDLEESIPEGMVDAASYAANLTDSAEAPKGSPGSWWKKELSGSSSAPKLEYTVRTDTQSPTNTGSPSSPQQKSEGLGSRHRPVARVSPHCKRSEAEAKPSGSQTVNLTGRANDPCDLDSRVQATSVKVTVAGFQPGGAVEKESLGKLTTGDACVSTSCELASALSHLDASHLTENLPKAASELGQQPMTELDSSSDLISSPGKKGAAHPDPSKTSVDTGQVSRPENPSQPASPRVTKCKARSPVRLPHEGSPSPGEKAAAPPDYSKTRSASETSTPHNTRRVAALRGAGPGAEGMTPAGAVLPGDPLTSQEQRQGAPGNHSKALEMTGIHAPESSQEPSLLEGADSVSSRAPQASLSMLPSTDNTKEACGHVSGHCCPGGSRESPVTDIDSFIKELDASAARSPSSQTGDSGSQEGSAQGHPPAGAGGGSSCRAEPVPGGQTSSPRRAWAAGAPAYPQWASQPSVLDSINPDKHFTVNKNFLSNYSRNFSSFHEDSTSLSGLGDSTEPSLSSMYGDAEDSSSDPESLTEAPRASARDGWSPPRSRVSLHKEDPSESEEEQIEICSTRGCPNPPSSPAHLPTQAAICPASAKVLSLKYSTPRESVASPREKAACLPGSYTSGPDSSQPSSLLEMSSQEHETHADISTSQNHRPSCAEETTEVTSASSAMENSPLSKVARHFHSPPIILSSPNMVNGLEHDLLDDETLNQYETSINAAASLSSFSVDVPKNGESVLENLHISESQDLDDLLQKPKMIARRPIMAWFKEINKHNQGTHLRSKTEKEQPLMPARSPDSKIQMVSSSQKKGVTVPHSPPQPKTNLENKDLSKKSPAEMLLTNGQKAKCGPKLKRLSLKGKAKVNSEAPAANAVKAGGTDHRKPLISPQTSHKTLSKAVSQRLHVADHEDPDRNTTAAPRSPQCVLESKPPLATSGPLKPSVSDTSIRTFVSPLTSPKPVPEQGMWSRFHMAVLSEPDRGCPTTPKSPKCRAEGRAPRADSGPVSPAASRNGMSVAGNRQSEPRLASHVAADTAQPRPTGEKGGNIMASDRLERTNQLKIVEISAEAVSETVCGNKPAESDRRGGCLAQGNCQEKSEIRLYRQVAESSTSHPSSLPSHASQAEQEMSRSFSMAKLASSSSSLQTAIRKAEYSQGKSSLMSDSRGVPRNSIPGGPSGEDHLYFTPRPATRTYSMPAQFSSHFGREGHPPHSLGRSRDSQVPVTSSVVPEAKASRGGLPSLANGQGIYSVKPLLDTSRNLPATDEGDIISVQETSCLVTDKIKVTRRHYCYEQNWPHESTSFFSVKQRIKSFENLANADRPVAKSGASPFLSVSSKPPIGRRSSGSIVSGSLGHPGDAAARLLRRSLSSCSENQSEAGTLLPQMAKSPSIMTLTISRQNPPETSSKGSDSELKKSLGPLGIPTPTMTLASPVKRNKSSVRHTQPSPVSRSKLQELRALSMPDLDKLCSEDYSAGPSAVLFKTELEITPRRSPGPPAGGVSCPEKGGNRACPGGSGPKTSAAETPSSASDTGEAAQDLPFRRSWSVNLDQLLVSAGDQQRLQSVLSSVGSKSTILTLIQEAKAQSENEEDVCFIVLNRKEGSGLGFSVAGGTDVEPKSITVHRVFSQGAASQEGTMNRGDFLLSVNGASLAGLAHGNVLKVLHQAQLHKDALVVIKKGMDQPRPSARQEPPTANGKGLLSRKTIPLEPGIGRSVAVHDALCVEVLKTSAGLGLSLDGGKSSVTGDGPLVIKRVYKGGAAEQAGIIEAGDEILAINGKPLVGLMHFDAWNIMKSVPEGPVQLLIRKHRNSS", "length": 2839 }, "evidence": [ { "id": "HGNC:18486", "url": "https://alliancegenome.org/gene/HGNC:18486#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060526-297", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-297#orthology", "database": "AGR" }, { "id": "MGI:1922394", "url": "https://alliancegenome.org/gene/MGI:1922394#orthology", "database": "AGR" }, { "id": "RGD:619958", "url": "https://alliancegenome.org/gene/RGD:619958#orthology", "database": "AGR" }, { "id": "FB:FBgn0087007", "url": "https://alliancegenome.org/gene/FB:FBgn0087007#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O54824-1", "protein_name": "Pro-interleukin-16", "gene_name": "Il16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPHGHSGKSRKSTKFRSISRSLILCNAKTSDDGSSPDEKYPDPFETSLCQGKEGFFHSSMQLADTFEAGLSNIPDLALASDSAQLAAAGSDRGKHCRKMFFMKESSSTSSKEKSGKPEAQSSSFLFPKACHQRTRSNSTSVNPYSAGEIDFPMTKKSAAPTDRQPYSLCSNRKSLSQQLDYPILGTARPTRSLSTAQLGQLSGGLQASVISNIVLMKGQAKGLGFSIVGGKDSIYGPIGIYVKSIFAGGAAAADGRLQEGDEILELNGESMAGLTHQDALQKFKQAKKGLLTLTVRTRLTTPPSLCSHLSPPLCRSLSSSTCGAQDSSPFSLESPASPASTAKPNYRIMVEVSLKKEAGVGLGIGLCSIPYFQCISGIFVHTLSPGSVAHLDGRLRCGDEIVEINDSPVHCLTLNEVYTILSHCDPGPVPIIVSRHPDPQVSEQQLKEAVAQAVEGVKFGKDRHQWSLEGVKRLESSWHGRPTLEKEREKHSAPPHRRAQKIMVRSSSDSSYMSGSPGGSPCSAGAEPQPSEREGSTHSPSLSPGEEQEPCPGVPSRPQQESPPLPESLERESHPPLRLKKSFEILVRKPTSSKPKPPPRKYFKNDSEPQKKLEEKEKVTDPSGHTLPTCSQETRELLPLLLQEDTAGRAPCTAACCPGPAASTQTSSSTEGESRRSASPETPASPGKHPLLKRQARMDYSFDITAEDPWVRISDCIKNLFSPIMSENHSHTPLQPNTSLGEEDGTQGCPEGGLSKMDAANGAPRVYKSADGSTVKKGPPVAPKPAWFRQSLKGLRNRAPDPRRPPEVASAIQPTPVSRDPPGPQPQASSSIRQRISSFENFGSSQLPDRGVQRLSLQPSSGETTKFPGKQDGGRFSGLLGQGATVTAKHRQTEVESMSTTFPNSSEVRDPGLPESPPPGQRPSTKALSPDPLLRLLTTQSEDTQGPGLKMPSQRARSFPLTRTQSCETKLLDEKASKLYSISSQLSSAVMKSLLCLPSSVSCGQITCIPKERVSPKSPCNNSSAAEGFGEAMASDTGFSLNLSELREYSEGLTEPGETEDRNHCSSQAGQSVISLLSAEELEKLIEEVRVLDEATLKQLDSIHVTILHKEEGAGLGFSLAGGADLENKVITVHRVFPNGLASQEGTIQKGNEVLSINGKSLKGATHNDALAILRQARDPRQAVIVTRRTTVEATHDLNSSTDSAASASAASDISVESKEATVCTVTLEKTSAGLGFSLEGGKGSLHGDKPLTINRIFKGTEQGEMVQPGDEILQLAGTAVQGLTRFEAWNVIKALPDGPVTIVIRRTSLQCKQTTASADS", "length": 1322 }, "evidence": [ { "id": "RGD:1583872", "url": "https://alliancegenome.org/gene/RGD:1583872#orthology", "database": "AGR" }, { "id": "HGNC:5980", "url": "https://alliancegenome.org/gene/HGNC:5980#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-130103-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130103-3#orthology", "database": "AGR" }, { "id": "MGI:1270855", "url": "https://alliancegenome.org/gene/MGI:1270855#orthology", "database": "AGR" }, { "id": "FB:FBgn0087007", "url": "https://alliancegenome.org/gene/FB:FBgn0087007#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q14005-1", "protein_name": "Pro-interleukin-16", "gene_name": "IL16", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESHSRAGKSRKSAKFRSISRSLMLCNAKTSDDGSSPDEKYPDPFEISLAQGKEGIFHSSVQLADTSEAGPSSVPDLALASEAAQLQAAGNDRGKTCRRIFFMKESSTASSREKPGKLEAQSSNFLFPKACHQRARSNSTSVNPYCTREIDFPMTKKSAAPTDRQPYSLCSNRKSLSQQLDCPAGKAAGTSRPTRSLSTAQLVQPSGGLQASVISNIVLMKGQAKGLGFSIVGGKDSIYGPIGIYVKTIFAGGAAAADGRLQEGDEILELNGESMAGLTHQDALQKFKQAKKGLLTLTVRTRLTAPPSLCSHLSPPLCRSLSSSTCITKDSSSFALESPSAPISTAKPNYRIMVEVSLQKEAGVGLGIGLCSVPYFQCISGIFVHTLSPGSVAHLDGRLRCGDEIVEISDSPVHCLTLNEVYTILSHCDPGPVPIIVSRHPDPQVSEQQLKEAVAQAVENTKFGKERHQWSLEGVKRLESSWHGRPTLEKEREKNSAPPHRRAQKVMIRSSSDSSYMSGSPGGSPGSGSAEKPSSDVDISTHSPSLPLAREPVVLSIASSRLPQESPPLPESRDSHPPLRLKKSFEILVRKPMSSKPKPPPRKYFKSDSDPQKSLEERENSSCSSGHTPPTCGQEARELLPLLLPQEDTAGRSPSASAGCPGPGIGPQTKSSTEGEPGWRRASPVTQTSPIKHPLLKRQARMDYSFDTTAEDPWVRISDCIKNLFSPIMSENHGHMPLQPNASLNEEEGTQGHPDGTPPKLDTANGTPKVYKSADSSTVKKGPPVAPKPAWFRQSLKGLRNRASDPRGLPDPALSTQPAPASREHLGSHIRASSSSSSIRQRISSFETFGSSQLPDKGAQRLSLQPSSGEAAKPLGKHEEGRFSGLLGRGAAPTLVPQQPEQVLSSGSPAASEARDPGVSESPPPGRQPNQKTLPPGPDPLLRLLSTQAEESQGPVLKMPSQRARSFPLTRSQSCETKLLDEKTSKLYSISSQVSSAVMKSLLCLPSSISCAQTPCIPKEGASPTSSSNEDSAANGSAETSALDTGFSLNLSELREYTEGLTEAKEDDDGDHSSLQSGQSVISLLSSEELKKLIEEVKVLDEATLKQLDGIHVTILHKEEGAGLGFSLAGGADLENKVITVHRVFPNGLASQEGTIQKGNEVLSINGKSLKGTTHHDALAILRQAREPRQAVIVTRKLTPEAMPDLNSSTDSAASASAASDVSVESTAEATVCTVTLEKMSAGLGFSLEGGKGSLHGDKPLTINRIFKGAASEQSETVQPGDEILQLGGTAMQGLTRFEAWNIIKALPDGPVTIVIRRKSLQSKETTAAGDS", "length": 1332 }, "evidence": [ { "id": "RGD:1583872", "url": "https://alliancegenome.org/gene/RGD:1583872#orthology", "database": "AGR" }, { "id": "HGNC:5980", "url": "https://alliancegenome.org/gene/HGNC:5980#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-130103-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130103-3#orthology", "database": "AGR" }, { "id": "MGI:1270855", "url": "https://alliancegenome.org/gene/MGI:1270855#orthology", "database": "AGR" }, { "id": "FB:FBgn0087007", "url": "https://alliancegenome.org/gene/FB:FBgn0087007#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QZR8-1", "protein_name": "PDZ domain-containing protein 2", "gene_name": "Pdzd2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPITQDNALLHLPLLYEWLQNSLREGGDSPEQRLCQAAIQKLQEYIQLNLAVDESTVPPDHSPPEMEICTVYLTKQLGDTETVGLSFGNIPVFGDYGEKRRGGKKRKTHQGPVLDVGCIWVTELRKNSPAGKSGKVRLRDEILSLNGQLMVGVDVTGASYLAEQCWNGGFIYLIMLRRFKQKAHVTYNGNSGNSSEPGETPTLELGDQTSKKGKRTRKFGVISRPSISKTPEDSKSSSGCDTADDPNSELENGADPELGNGHAFELENGPHSLKDVAGPHLERSEADSEVELRVPKTEAPLSDSNDKRRFSKTGKTDFQSSDCLAREEVGRIWKMELLKESDGLGIQVSGGRGSKRSPHAIVVTQVKEGGAAHRDGRLSLGDELLVINGHLLVGLSHEEAVAILRSATGMVQLVVASKMPGSEESQDVGSSEESKGNLESPKQGNCKTKLKSRLSGGVHRLESVEEYNELMVRNGDPRIRMLEVSRDGRKHSLPQLLDSTGTSQEYHIVKKSTRSLSTTHVESPWRLIRPSVISIIGLYKEKGKGLGFSIAGGRDCIRGQMGIFVKTIFPNGSAAEDGRLKEGDEILDVNGIPIKGLTFQEAIHTFKQIRSGLFVLTVRTKLLSPSLTPCSTPTHMSRSSSPSFNTNSGGTPAGGGQEEGGSSSLGRKAPGPKDRIVMEVTLNKEPRVGLGIGACCLALENSPPGIYIHSLAPGSVAKMESNLSRGDQILEVNSVNVRHAALSKVHAILSKCPPGPVRLVIGRHPNPKVSEQEMDEVIARSTYQESREANSSPGLGTPLKSPSLAKKDSLLSESELSQYFVHDGQGSLSDFVVAGSEDEDHPGSGYETSEDGSLLPVPSAHKARANSLVTLGSQRTSGLLHKQVTVARQASLPGSPQVLRNPLLRQRRVRCYDSNGGSDDEDFDGEGDCISLPGVLPGPGKPLVEDDTRPALTTSSKSIDVNKQEERLQKPLVSKACSVPLLGSSLDSEHSILNGAGGTPPKVASLPGSGETPKNGPRGSGRKEMSGSRSSPKLEYRVPTDTQSPRSPENHTSPPQKSENLVSRHKPVARISPHYKRSDAEEAPGGTANGPCAQDLKVQASPVKDPVTSRQPGGTAEKELRGNPTPGDSSVPTNCGPASTPCHPNIGLPTENPQGAAPECGPHPGTGWDGSSEHLCSPGKSREVHPDSSETPTVAEQVHQPESLSQPVSPRTSEPESQGISKMKPPSQRCVSPREKASTPPDSSRAWAAPGDSSPSTRRIAVPMSTGAAPATAIPQASLVSQERSRGLSGPSKGLGTKELCIPKSLKDGALLEDTAPASGKMSHASSPSGPVATERTLSGSPENPVTDIDNFIEEASEARLSQSPQKADCRAHGDTFESQPPGGAGSSSSHHAQMVRSDQTSSPRKTGGTGSPPPQQWALQPSVLDSIHPDKHLAVNKTFLNNYSRNFSNFHEDSISLSGPGGSSEPSPSSMYGNAEDSSSDPESLAEDPGAAARNNWSPPLSPESSPKEGSSESEDERIEICSTDGCPGTPVTAPPPTQVALCPVLPVQQRAVCKPVGDICERACFVPGASRTSIPDSSQPFSFLDVSSEEPETWASINASQNHMPVCTEGIMDVTSTSSNMGDSQSSQMTRHCRNAPFVLGNPDMVNDLGRDLLDEGAPKEGAAAASVMRSVFALGAEGPKNGEAVLADLHIAERGNLEDLLQKPKTISRRPILTWFKEINKDSQGSHLRSTSEKEQSSMLALGPGSKANMVNTGHRKGVTVPKSPPSRQKSQENKDLPPKSPVETLGNCQKPKCSPKLKRLNSKGKASPEVPVAISTKGSRNDHRKTLPSPQASHKMFSKAVSHRLHIADQEEPKNTAGDTPKPPQCVPESKPPQAALGSLRTSASDTSIRTFTSPLTSPKLLPEQGANSRFHMAVYLESDTSCPTTSRSPRSGPEGKAPHANSGSASPPASRASLALAGIRQSKQFTPGRADLLVSEATQPQGICEKGAEKKVSDPPQRTNQLKIVEISSERVPKNACGDRPPESDRKGGFLTQNNCQEKSAIRLRQSEESSPEHTPFPPSQASQVEREIRWSFSMAKPATSSSSSLQLPAKLPESFQGKSSQMPASVGVPKNGVPIGLAGEESPYFTPRPATRTYSMPAQFSSHFGREGPSPHSPSHSPQDPQVPAMGGKLSEKTAKGVTNGQGVYSVKPLLETSKNLSPVDGRDVSADPETSCLIPDKVKVTRRQYCCEQSWPHESTSFFSVKQRIKSFENLANSDRPTAKCATSPFLSVSSKPPINRRSSGSIPSGSPSDMTSRSLRRSLSSCSESQSEASSLLPQMTKSPSSMTLTVSRQNPPDTSNKGPSPDPKKSLVPVGIPTSTVSPASPSKRNKSSVRHAQPSPVSRSKLQERRTLSMPDLDKLCNGEDDSASPGAVLFKTQLEITPRRSKGSQATSPAGSPARGHADFNGSTFLSCPMNGGTRAYTKGNSPPASEPAIATGSREEGESVWATPSGKSWSVSLDRLLASVGNQQRLQGILSLVGSKSPILTLIQEAKAQSETKEDICFIVLNKKEGSGLGFSVAGGADVEPKSVMVHRVFSQGVASQEGTVSRGDFLLSVNGTSLAGLAHSEVTKVLHQAELHKHALMIIKKGNDQPGPSFKQEPPSANGKGPFPRRTLPLEPGAGRNGAAHDALCVEVLKTSAGLGLSLDGGKSSVSGEGPLVIKRVYKGGAAERAGTIEAGDEILAINGKPLVGLVHFDAWNIMKSVPEGPVQLVIRKHRDS", "length": 2766 }, "evidence": [ { "id": "HGNC:18486", "url": "https://alliancegenome.org/gene/HGNC:18486#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060526-297", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-297#orthology", "database": "AGR" }, { "id": "MGI:1922394", "url": "https://alliancegenome.org/gene/MGI:1922394#orthology", "database": "AGR" }, { "id": "RGD:619958", "url": "https://alliancegenome.org/gene/RGD:619958#orthology", "database": "AGR" }, { "id": "FB:FBgn0087007", "url": "https://alliancegenome.org/gene/FB:FBgn0087007#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VUE8", "url": "https://www.uniprot.org/uniprotkb/Q9VUE8" } ], "pmid": "" }, { "name": "apical part of cell", 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] } ], "protein_names": [ { "name": "Vacuolar ATPase assembly protein VMA22", "type": "recommended", "evidence": [ { "id": "Q9VUE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUE9/entry#names_and_taxonomy" } ] }, { "name": "CG9592-PB", "type": "synonym", "evidence": [ { "id": "NP_648706", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648706" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_648706", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648706" } ] } ], "function": [], "disease": [ { "disease_id": "DOID:0070267", "recommended_name": { "id": "DOID:0070267", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070267", "name": "congenital disorder of glycosylation type IIo", "description": "A congenital disorder of glycosylation type II that has_material_basis_in an autosomal recessive mutation of the CCDC115 gene on chromosome 2q21.1." }, 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31996:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "NP_648706", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648706", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VUE9", "url": "https://www.uniprot.org/uniprotkb/Q9VUE9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VUE9-1", "url": "https://www.uniprot.org/uniprotkb/Q9VUE9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIQLIEDLELLHSQVNKESCRAQLVLARVRLHQGFERIPAEAQLPRGRPYKALTRVVENDNYWGKVFKMIRLPVNPILGYLLPVRNIFGCLVSDNLRIANRHWDNCLDLVVECANVQRKLQSTINSIENLRNLLNQRQCPQMSNDKLKVILK", "length": 152, "header": "tr|Q9VUE9-1|Q9VUE9_DROME Isoform 1 of Vacuolar ATPase assembly protein VMA22 OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG9592 PE=4 SV=2 CANONICAL=Q9VUE9-1" }, "isoforms": [ { "isoform_ac": "Q9VUE9-1", "url": "https://www.uniprot.org/uniprotkb/Q9VUE9/entry#Q9VUE9-1", "sequence": { "sequence": "MIQLIEDLELLHSQVNKESCRAQLVLARVRLHQGFERIPAEAQLPRGRPYKALTRVVENDNYWGKVFKMIRLPVNPILGYLLPVRNIFGCLVSDNLRIANRHWDNCLDLVVECANVQRKLQSTINSIENLRNLLNQRQCPQMSNDKLKVILK", "length": 152, "header": "tr|Q9VUE9-1|Q9VUE9_DROME Isoform 1 of Vacuolar ATPase assembly protein VMA22 OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG9592 PE=4 SV=2 CANONICAL=Q9VUE9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VUE9", "url": "https://www.uniprot.org/uniprotkb/Q9VUE9" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VUE9", "url": "https://www.uniprot.org/uniprotkb/Q9VUE9" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUE9", "url": "https://www.uniprot.org/uniprotkb/Q9VUE9" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUE9", "url": "https://www.uniprot.org/uniprotkb/Q9VUE9" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VUE9", "url": "https://www.uniprot.org/uniprotkb/Q9VUE9" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VUE9", "url": "https://www.uniprot.org/uniprotkb/Q9VUE9" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VUE9", "url": "https://www.uniprot.org/uniprotkb/Q9VUE9" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUE9", "url": "https://www.uniprot.org/uniprotkb/Q9VUE9" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUE9", "url": "https://www.uniprot.org/uniprotkb/Q9VUE9" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VUE9", "url": "https://www.uniprot.org/uniprotkb/Q9VUE9" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VUE9", "url": "https://www.uniprot.org/uniprotkb/Q9VUE9" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], 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"Q9VUG2-1", "uniprot_ac": "Q9VUG2", "uniprot_id": "Q9VUG2_DROME", "mass": { "chemical_mass": 41498.0, "monoisotopic_mass": 41498.0 }, "refseq": { "ac": "NP_648711", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648711" }, "gene_names": [ { "name": "Dmel\\CG4914", "type": "recommended", "evidence": [ { "id": "Q9VUG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUG2" } ] }, { "name": "CG4914", "type": "synonym", "evidence": [ { "id": "NP_648711", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648711" }, { "id": "Q9VUG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUG2" } ] }, { "name": "Dmel\\CG4914", "type": "synonym", "evidence": [ { "id": "NP_648711", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648711" } ] }, { "name": "Dmel_CG4914", "type": "synonym", "evidence": [ { "id": "Q9VUG2", "database": "UniProtKB", "url": 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"CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0036436", "url": "https://flybase.org/reports/FBgn0036436", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "39597", "url": "https://www.ncbi.nlm.nih.gov/gene/39597", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018114", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018114", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG4914", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG4914", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FGAFNRN", "url": "https://omabrowser.org/oma/group/FGAFNRN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VUG2", "url": "https://www.orthodb.org/?gene=Q9VUG2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24252", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24252", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24252:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24252:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_648711", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648711", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VUG2", "url": "https://www.uniprot.org/uniprotkb/Q9VUG2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VUG2-1", "url": "https://www.uniprot.org/uniprotkb/Q9VUG2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMMLHLRHWPLVLAMASCLLFTAATSATPATPATPATSAPPATSTATSSLSSIPGKYQALGAAHHQAKKLKIGDVNASSSDANKPVFRQNPIKNWFGAFNRNNSPAAQNQTSPTCSCRCGERNDESRIVGGTTTGVSEYPWMARLSYFNRFYCGGTLINDRYVLTAAHCVKGFMWFMIKVTFGEHDRCNDKERPETRFVLRAFSQKFSFSNFDNDIALLRLNDRVPITSFIRPICLPRVEQRQDLFVGTKAIATGWGTLKEDGKPSCLLQEVEVPVLDNDECVAQTNYTQKMITKNMMCSGYPGVGGRDSCQGDSGGPLVRLRPDDKRFEQIGIVSWGNGCARPNYPGVYTRVTKYLDWIVENSRDGCFCDEDY", "length": 374, "header": "tr|Q9VUG2-1|Q9VUG2_DROME Isoform 1 of Peptidase S1 domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG4914 PE=4 SV=2 CANONICAL=Q9VUG2-1" }, "isoforms": [ { "isoform_ac": "Q9VUG2-1", "url": "https://www.uniprot.org/uniprotkb/Q9VUG2/entry#Q9VUG2-1", "sequence": { "sequence": "MMMLHLRHWPLVLAMASCLLFTAATSATPATPATPATSAPPATSTATSSLSSIPGKYQALGAAHHQAKKLKIGDVNASSSDANKPVFRQNPIKNWFGAFNRNNSPAAQNQTSPTCSCRCGERNDESRIVGGTTTGVSEYPWMARLSYFNRFYCGGTLINDRYVLTAAHCVKGFMWFMIKVTFGEHDRCNDKERPETRFVLRAFSQKFSFSNFDNDIALLRLNDRVPITSFIRPICLPRVEQRQDLFVGTKAIATGWGTLKEDGKPSCLLQEVEVPVLDNDECVAQTNYTQKMITKNMMCSGYPGVGGRDSCQGDSGGPLVRLRPDDKRFEQIGIVSWGNGCARPNYPGVYTRVTKYLDWIVENSRDGCFCDEDY", "length": 374, "header": "tr|Q9VUG2-1|Q9VUG2_DROME Isoform 1 of Peptidase S1 domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG4914 PE=4 SV=2 CANONICAL=Q9VUG2-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 28, "start_aa": "Thr", "end_pos": 28, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr28", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 31, "start_aa": "Thr", "end_pos": 31, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr31", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 34, "start_aa": "Thr", "end_pos": 34, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr34", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VUG2", "url": "https://www.uniprot.org/uniprotkb/Q9VUG2" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VUG2", "url": "https://www.uniprot.org/uniprotkb/Q9VUG2" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUG2", "url": "https://www.uniprot.org/uniprotkb/Q9VUG2" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUG2", "url": "https://www.uniprot.org/uniprotkb/Q9VUG2" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VUG2", "url": "https://www.uniprot.org/uniprotkb/Q9VUG2" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VUG2", "url": "https://www.uniprot.org/uniprotkb/Q9VUG2" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VUG2", "url": "https://www.uniprot.org/uniprotkb/Q9VUG2" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUG2", "url": "https://www.uniprot.org/uniprotkb/Q9VUG2" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUG2", "url": "https://www.uniprot.org/uniprotkb/Q9VUG2" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VUG2", "url": "https://www.uniprot.org/uniprotkb/Q9VUG2" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VUG2", "url": "https://www.uniprot.org/uniprotkb/Q9VUG2" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG4914", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG4914", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0B4JCS5-1", "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "CR30082", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKSLWIASFAFLVCLTPKLRAQFIDPNCGTTINLPPTNRIVGGRTADIGSNPWLAYLHKNSSLVCTGTLITKRFVLTAAHCLHSFHLLTVRLGEYDTSTRIDCTSEFCIPTYEEYSVENAYIHTFFGGRQDSRNDIGLLKLNGTVVYKLFIRPICLFRDPGQVPYSSTYEAAGWGKIDLINTATVLQTVNLIRLDQSDCERSLRTSLSYGQFCAGQWRADTCSGDSGGPLSRKMSNGRITRTVQLGIVSYGHYLCRGPGVYTYVPSFTNWILSITRWTQN", "length": 280 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-051127-11", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-051127-11#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A0A0B4K7A9-1", "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "CG5302", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNVVVVGLTFFLLPLLGSTQFLDMACGIRAHSPSVPRVKNGTVASLTSSPWMAFLHSTDGRFICGGSLITNRLVLTAAHCFLDRTELVARLGEYDREEYEMCHDSYCTYRIEAMVERGFRHRHYNPMTMAYDIAILRLYRKVQYTDNIRPICIVIDPRWRKYIDSLDPLTGTGWGKTESEGDSAKLRTVDLARKHPEVCRRYATLSLTANQFCAGNERSNLCNGDSGGPVGALIPYGKSKRFVQVGIASFTNTQCVMVSVFTDVMSYVDWILAVHNYHK", "length": 279 }, "evidence": [ { "id": "HGNC:29994", "url": "https://alliancegenome.org/gene/HGNC:29994#orthology", "database": "AGR" }, { "id": "HGNC:24465", "url": "https://alliancegenome.org/gene/HGNC:24465#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A0A4D6K1E7-1", "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "Dmel\\CG11836", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSLKYIIFFWMLTANYSSVLSLEYSKGFNESDAINTIHTGHNKRTSKFLFDTIFRISSGVSNAFGLSDTEDEVEYTENSSLKNCDCDCGFSNEEIRIVGGKPTGVNQYPWMARIVYDGKFHCGGSLLTKDYVLSAAHCVKKLRKSKIRVIFGDHDQEITSESQAIQRAVTAVIKHKSFDPDTYNNDIALLRLRKPISFSKIIKPICLPRYNYDPAGRIGTVVGWGRTSEGGELPSIVNQVKVPIMSITECRNQRYKSTRITSSMLCAGRPSMDSCQGDSGGPLLLSNGVKYFIVGIVSWGVGCGREGYPGVYSRVSKFIPWIKSNLENTCLCS", "length": 333 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-051127-11", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-051127-11#orthology", "database": "AGR" }, { "id": "HGNC:14118", "url": "https://alliancegenome.org/gene/HGNC:14118#orthology", "database": "AGR" }, { "id": "HGNC:14120", "url": "https://alliancegenome.org/gene/HGNC:14120#orthology", "database": "AGR" }, { "id": "HGNC:12019", "url": "https://alliancegenome.org/gene/HGNC:12019#orthology", "database": "AGR" }, { "id": "HGNC:14134", "url": "https://alliancegenome.org/gene/HGNC:14134#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141212-262", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141212-262#orthology", "database": "AGR" }, { "id": "RGD:620766", "url": "https://alliancegenome.org/gene/RGD:620766#orthology", "database": "AGR" }, { "id": "RGD:1310135", "url": "https://alliancegenome.org/gene/RGD:1310135#orthology", "database": "AGR" }, { "id": "RGD:628625", "url": "https://alliancegenome.org/gene/RGD:628625#orthology", "database": "AGR" }, { "id": "MGI:3521861", "url": "https://alliancegenome.org/gene/MGI:3521861#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A0A8I5ZM18-1", "protein_name": "Transmembrane protease serine", "gene_name": "Tmprss11c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARGQPRRSEEPWTALRNRTECKTKIKLTKCGKITLGILTAVIAAVVIGLIAYFAACGKTPFYYHVSFKVNNIDYDSKFAKPYSQEYMDLNKRIVSLMNETFHESKLRKQYVKAHTVQVSKAKGKVVIHGVLKFKSCYKNNVEKFWDSVETILYQKLKSQTRLLIDSSSFKFSDIAMPIAEDLLNTCCGRRTITPGGHKVAGGQDAEEGEWPWQASLQQNNVHRCGATLISNSWLITAAHCFVRSANPKDWKVSFGFLLSKPQAQRAVKSIVIHENYSYPAHNNDIAVVRLSSPVLYENNIRRACLPEATQKFPPNSDVVVTGWGTLKSDGDSPNILQKGRVKIIDNKTCNSGKAYGGVITPGMLCAGFLEGRVDACQGDSGGPLVSEDSKGIWFLAGIVSWGDECALPNKPGVYTRVTHYRDWISSKTGL", "length": 431 }, "evidence": [ { "id": "MGI:3521861", "url": "https://alliancegenome.org/gene/MGI:3521861#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AAZ3-1", "protein_name": "Tryptase gamma 1", "gene_name": "Tpsg1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALGPYCGFLLLLAVPGISCEALQSGCGQPQVSHAGSRIVGGHAAQAGAWPWQASLRLQKVHVCGGSLLSPEWVLTAAHCFSGSVNSSDYEVHLGELTITLSPHFSTVKQIIMYSSAPGPPGSSGDIALVQLATPVALSSQVQPVCLPEASADFHPGMQCWVTGWGYTQEGEPLKPPYNLQEAKVSVVDVETCSQAYSSSNGSLIQSDMLCAWGPGDACQDDSGGPLVCRVAGIWQQAGVVSWGEGCGRPDRPGVYARVTAYVNWIHRHILEPGGSGMQGLSWIPLLAGLFLPSLFLLLVSGVVMAKYWLGSPSHPALEF", "length": 320 }, "evidence": [ { "id": "HGNC:14134", "url": "https://alliancegenome.org/gene/HGNC:14134#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141212-262", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141212-262#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M1N826-1", "protein_name": "Uncharacterized protein LOC641564 precursor", "gene_name": "", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKMNTALTVVGALLVNIAGSLCQLNVCGRAPLNTKIVGGQNAGAGSWPWQVSLQSPTYGGHFCGGSLINKDWVLSAAHCFQDSLGTVKVKLGLQSQSGSNPYQITKTVVQVINHPNYNNPSNDNDIALVKLDSSVTFNDYIEPVCLAAAGNTYAAGTLSWVTGWGKLSSAANQIPDILQEVEIPIVSNSDCKRAYPGEITSNMICAGLLDQGGKDSCQGDSGGPMVSRNGSQWIQSGIVSFGRGCAEPGYPGVYARVSQYQDWITSSTGSSNPPGFVEFHSSGFRSTSNLFLLSISLTLSIIPFASVLSS", "length": 310 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-051127-11", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-051127-11#orthology", "database": "AGR" }, { "id": "FB:FBgn0036436", "url": "https://alliancegenome.org/gene/FB:FBgn0036436#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1Q1Z2-1", "protein_name": "Serine protease 33", "gene_name": "si:dkey-16l2.17", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTDSCLQLFLMATGLSTCLAQVCGRPPLGKRIVGGVEASPGSWPWQVDIQMGSNGHVCGGSIIAKNWVLSAAHCFPNPSEVSAYTLYMGRHLLNGYNQFEKVSYVQRVVIPEGYTDPQGGRDVALVQLRAPVSWTDRIQPVCLPFADFQFNSGTLCYVTGWGHKQEGVSLTGAAALREVEVPIIDQSSCQFMYQILSSDSSTVDILSDMICAGYKEGGKDSCQGDSGGPLVCPVGNGTWIQAGVVSFGLGCAQKNRPGIYSRVSSFEKLIRTTVPEAYFLGHACRSESQTPLVTVLSLALVLIWR", "length": 305 }, "evidence": [ { "id": "HGNC:14120", "url": "https://alliancegenome.org/gene/HGNC:14120#orthology", "database": "AGR" }, { "id": "HGNC:12019", "url": "https://alliancegenome.org/gene/HGNC:12019#orthology", "database": "AGR" }, { "id": "MGI:96943", "url": "https://alliancegenome.org/gene/MGI:96943#orthology", "database": "AGR" }, { "id": "HGNC:14134", "url": "https://alliancegenome.org/gene/HGNC:14134#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141212-262", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141212-262#orthology", "database": "AGR" }, { "id": "FB:FBgn0036436", "url": "https://alliancegenome.org/gene/FB:FBgn0036436#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9QK25-1", "protein_name": "Transmembrane protease serine 3 isoform X1", "gene_name": "tmprss3a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADPEELESMAGVDVGADVNGESIPCIESTQTDGQETEHQIYPNQSEEVSVTETDMSSVDVLQNVSHLDGSSASPVPEVQPTSEVPSKEPLTETHSTQPSLSLPVTKVQPFVTEEKTLRSSLFARRMEILIITCVLLTLIIVLGIGLGVGLSCAGKFRCFSSRCISILAQCDGHFDCEHGEDELSCVRLSGKSSVLQVLNDGVWRTVCAENWNFNLSLSACKQLGYSRFVESKALPLSFIEQDYQNNLISIGLNQTSFQQPVKIHNITNSSKTKCSLGMVTALKCIACGSRPKFSARIVGGNLSAEGQFPWQVSLHFQNEHLCGGSIITSRWILTAAHCVYGIAYPMYWMVYAGLTELPLNAVKAFAVEKIIYHSRYRPKGLDHDIALMKLAQPLTFNGMVEPICLPNFGEQFEDGKMCWISGWGATEDGGDASVSQHCASVPLISNKACSQPEVYQGYLTAGMICAGYLDGGTDSCQGDSGGPLACEDSSIWKLVGATSWGQGCAEKNKPGVYTRITQSLTWIHLQMEREEILHPLTVSSNY", "length": 543 }, "evidence": [ { "id": "RGD:1310135", "url": "https://alliancegenome.org/gene/RGD:1310135#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A1ZAG8-1", "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "Dmel\\CG33458", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKLIPALLALLILGHGISLGYSYLLEWDCGISKYTYRITGGRDSPLMLNPWLAYLHINSKFICGGSLLNHWFVLTAAHCFRDKNAKVLVRLGENDASQKIDCNESECAAPHLEYMIMQKLIHPLYRTAHYYDIALAKLNRYVVYTDSIRPICLMLNPNWQVYVDTIRYFIITGWGATNASEVSDKLQLTRIPQIDRFTCRYWFGYMVDRTHICAGESKHYVGKGDSGGPLGSMVDYKYAKRFFQFGIVSHLRQPFHGVSVFTNILSYSNWIHRTIITNSGH", "length": 281 }, "evidence": [ { "id": "HGNC:29994", "url": "https://alliancegenome.org/gene/HGNC:29994#orthology", "database": "AGR" }, { "id": "HGNC:24465", "url": "https://alliancegenome.org/gene/HGNC:24465#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A1ZAG9-1", "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "HDC06756", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKYISYLLVSSIIANQLLYGLAVLLEPNCGQIPFRMRIFGGMDAGLVSTPWMAFLHNHLQFLCGGSLITSEFVLTAAHCVMPTPKNLTVRLGEYDWTRQMDSINPKHRHREYMVTRIYTHPSYRSIAAYDIALLKLNQTVEYTVAIRPICLVLPENFHEWYWLVDSVEDFTLTGWGATKTEPVSQVLQSANLTQIDRGTCHDRYGHSVDHTHICAGSSKSFACVGDSGSPLAMKVVHNRRYIHAQVGIVSRGPKNCDGVTVFTNVVSFTEWIFRTTLYDAKYMS", "length": 284 }, "evidence": [ { "id": "HGNC:29994", "url": "https://alliancegenome.org/gene/HGNC:29994#orthology", "database": "AGR" }, { "id": "HGNC:24465", "url": "https://alliancegenome.org/gene/HGNC:24465#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A8DY75-1", "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "Dmel\\CG8172", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLPLPRHSKDTWLRLVVLCALICLSAPRRADALGYPSAQQEHDMLILDALSRRSGTGYYGENSVMEMLSRMIPQSCRFRGHKFECGLSISCVLGGGKPLDLCSGGMIWSCCVDKDLDAEESPHAAPVNNTSDIIHLHDIYPDLSTNANKPQHHLHHHSGNGLSAAPSTSSTASSSARPAYPSSYYGTKRPTHYSGSNPYKPGSSAGGSSRPSSSSSSSLNSWEHETGGHLGSISGITNHLDSFFDAESQAPLDSAGAPPPHEPLPNAQAFAVGNVLDLNAGEAADEYQSGGSGGYHDASYRPVPGCGEVYTRSNRIVGGHSTGFGSHPWQVALIKSGFLTRKLSCGGALISNRWVITAAHCVASTPNSNMKIRLGEWDVRGQEERLNHEEYGIERKEVHPHYNPADFVNDVALIRLDRNVVYKQHIIPVCLPPSTTKLTGKMATVAGWGRTRHGQSTVPSVLQEVDVEVISNDRCQRWFRAAGRREAIHDVFLCAGYKDGGRDSCQGDSGGPLTLTMDGRKTLIGLVSWGIGCGREHLPGVYTNIQRFVPWINKVMANDNA", "length": 561 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-051127-11", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-051127-11#orthology", "database": "AGR" }, { "id": "HGNC:14118", "url": "https://alliancegenome.org/gene/HGNC:14118#orthology", "database": "AGR" }, { "id": "HGNC:14120", "url": "https://alliancegenome.org/gene/HGNC:14120#orthology", "database": "AGR" }, { "id": "HGNC:12019", "url": "https://alliancegenome.org/gene/HGNC:12019#orthology", "database": "AGR" }, { "id": "HGNC:14134", "url": "https://alliancegenome.org/gene/HGNC:14134#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "D3ZY65-1", "protein_name": "Transmembrane protease serine 3", "gene_name": "Tmprss3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAPETVEVEPEPNIRGPEIVTMGENDPPAAEAPFSFRSLFGLDDLKISSVAPDGDAVAAQILSLLPLKFFPIIVIGIIALILALAIGLGIHFDCSGKYRCHSSFKCIELTARCDGVPNCKDGEDEYRCVRVSGQRAALQVFTAAAWRTMCSDDWKSHYAKIACAQLGFPSYVSSDHLRVDALEEQFQGDFVSINHLLPDDKVTALHHSVYMREGCTSGHVVTLKCSACGMRTGYSPRIVGGNVSSLTQWPWQVSLQFQGYHLCGGSVITPLWIVTAAHCVYDLYHPKSWTVQVGLVSLMDSPVPSHLVEKIIYHSKYKPKRLGNDIALMKLSEPLTFDETIQPICLPNSEENFPDGKLCWTSGWGATEDGGDASPVLNHAAVPLISNKICNHRDVYGGIISPSMLCAGYLKGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRITSFLDWIHEQLERDLKT", "length": 475 }, "evidence": [ { "id": "RGD:1310135", "url": "https://alliancegenome.org/gene/RGD:1310135#orthology", "database": "AGR" }, { "id": "FB:FBgn0036436", "url": "https://alliancegenome.org/gene/FB:FBgn0036436#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AAE4-1", "protein_name": "Serine protease 22", "gene_name": "Prss22", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVISRPPLALGGDQFRTLILLVLLTSTATVSAANIRGSPDCGKPQQLNRVVGGEDSADAQWPWIVSILKNGSHHCAGSLLTNRWVVSAAHCFSSNMDKPSPYSVLLGAWKLGNPGPRSQKVGIASVLPHPRYSRKEGTHADIALVRLERPIQFSERILPICLPDSSVHLPPNTNCWIAGWGSIQDGVPLPRPQTLQKLKVPIIDPELCKSLYWRGAGQEAITEDMLCAGYLEGKRDACLGDSGGPLMCQVDDHWLLTGIISWGEGCAERNRPGVYTSLLAHRPWVQRIVQGVQLRGRLADSGDTGSS", "length": 307 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-141212-262", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141212-262#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AB49-1", "protein_name": "Serine protease 33", "gene_name": "Prss33", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRDASHLQILLLVVLGARMQECAACGQPRMSSRIVGGRDAQDGEWPWQTSIQHRGAHVCGGSLIAPQWVLTAGHCFSRRVLPSEYSVLLGALSLDVTSSHELLVPVLRVLLPPDYSEDEARGDLALLQLSHPVSLSARIQPVCLPAPGSHPPPGSPCWVTGWGSLSPGVPLPKGRPLQGVRVPLLDSRACDRLYHMGANVPKSERIVLPGNLCAGYRRGHKDACQGDSGGPLTCMESGRWVLVGVVSWGKGCALPNRPGVYTNVAKYSPWIQARLSL", "length": 277 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-141212-262", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141212-262#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9Q409-1", "protein_name": "Serine protease 32", "gene_name": "Prss32", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MELALPAILFTFFPGVLLGSEVLPTDSDSPSTTTGRRSIDLDSVCGRPRTSGRIVSGQDAQLGRWPWQVSVRENGAHVCGGSLIAEDWVLTAAHCFNQGQSLSIYTVLLGTISSYPEDNEPKELRAVAQFIKHPSYSADEHSSGDIALVQLASPISFNDYMLPVCLPKPGDPLDPGTMCWVTGWGHIGTNQPLPPPFTLQELQVPLIDAETCNTYYQENSIPGTEPVILEGMLCAGFQEGKKDACNGDSGGPLVCDINDVWIQAGVVSWGSDCALFKRPGVYTNVSVYISWIQNTMWNLPMEGRGFSPSLSGTPLLGLLLFLTSLSSAFFLLGP", "length": 334 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-141212-262", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141212-262#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1LSP0-1", "protein_name": "Transmembrane protease serine 5", "gene_name": "Tmprss5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSTLDDQCPMEIRCTEEGPGPGIFRAELGDQQQPISQSQRWCCLQRGCVILGALGLLAGAGVGSWLLVLYLWPAASPPVSVTLQEEEVTLSCPGVSSEEKLLPSLPKAVSFRINGEDLLLEVQVRARPDWLLVCHEGWNPALGMHICQSLGYFRLTQHKAVNLSDIKLNRSQEFAQLSARPGSLVEEAWQPSTNCPSGRIVSLKCSECGARPLASRIVGGQAVASGRWPWQASVMLGSRHTCGASVLAPYWVVTAAHCMYSFRLSRLSSWRVHAGLVSHSAVRQHQGTMVEKIIPHPLYSAQNHDYDVALLQLRTPINFSDTVSAVCLPAKEQHFPQGSQCWVSGWGHTDPSHTHSSDTLQDTMVPLLSTDLCNSSCMYSGALTHRMLCAGYLDGRADACQGDSGGPLVCPSGDTWHLVGVVSWGRGCAEPNRPGVYAKVAEFLDWIHDTVQVR", "length": 455 }, "evidence": [ { "id": "RGD:628625", "url": "https://alliancegenome.org/gene/RGD:628625#orthology", "database": "AGR" }, { "id": "FB:FBgn0036436", "url": "https://alliancegenome.org/gene/FB:FBgn0036436#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M2C4-1", "protein_name": "Transmembrane protease serine", "gene_name": "Tmprss11e", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYRSPVVRARKRTYVEPWVIGLISFLSLIVLAVCIGLTVHYVRYNHRRTYNYYSTLPFTSDKLYSEFGKEASKNFTEMSQRIETMVKNAFHKSPLRGQLSKAHIIKFSKEDDGVLAHMLLIFRIRSTEDPEVVHKIIEYVLREKLKYATGPPKVDPESVEIKKINKTESDNYLNHCCGTRRNKSTAQTSVRIVGGTSAEEGEWPWQSSLQWDGSHRCGATLISNTWLVSAAHCFRTHKDPSRWTASFGATLQPPKLTTGIRRIIVHEKYNYPSHDYDIALVELSRPVPCTNAVHKVCLPDANHEFQPGQRMFVTGFGALRNDGFAQNYLRQVQVDYIDTQTCNRPQSYNGAITPRMLCAGFLKGEKDACQGDSGGPLVTPDVRDVWYLAGVVSWGDECGQPNKPGVYTRVTAFRDWITSNTGI", "length": 423 }, "evidence": [ { "id": "HGNC:24465", "url": "https://alliancegenome.org/gene/HGNC:24465#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M6D3-1", "protein_name": "Transmembrane protease serine", "gene_name": "Tmprss11f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMYAPVEFSETEYPRIEYQRRQQQFWDPIRLALFTLAIVAIIGITIGIVTHFVVEDDKSFYYLASFQVTNIKYKENYGIRSSREFIERSHQIERMMSRIFRRSSGVGRFIKSHVIKISPDEQGVNILIVLMFRYPSTDSAEHIKKKIERTLYQSLKIKQFPLTINKPSFSLTPIDSKKMRNLLNSRCGIRMSSSNIPLPASSTTERIVQGRETAMEGEWPWQASLQLIGAGHQCGATLISNTWLLTAAHCFWKNRDPSKWIATFGTTITPPLVKRSVGRIIIHEEYHRDSNENDIALAQLTSRVEFSNVVQRVCLPDSSMKLPPKTSVFVTGFGSIVDDGPTQNKLRQARVETIGSDVCNQKDVYDGLITPGMLCAGFMEGKVDACKGDSGGPLVYDNRDIWYIVGIVSWGQSCALPNKPGVYTRVSKYRDWIASKTGL", "length": 439 }, "evidence": [ { "id": "HGNC:29994", "url": "https://alliancegenome.org/gene/HGNC:29994#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RAL3-1", "protein_name": "Protease, serine, 32", "gene_name": "Prss32", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELALAVILYTLLPGVLLGSEVLTTDSYSLSTQTGRSSIDLDSVCGRPRASGRIVSGQNAQLGQWPWQVSVREDGVHVCGGSLISEDWVLTAAHCFNQDQHLSAYTVLLGTISSYPEDNEPRELRAVAQYIKYPSYSAEEHSSGDIALLQLASPISFNDYMLPVCLPKPGDPLDPGTMCWVTGWGNIATNQPLPPPFTLQELQVPLIDAKTCNTYYQENSVPSTEQVILEDMLCAGFVEGKKDACNGDSGGPLVCDVNDVWIQAGVVSWGSDCALSNRPGVYTNVSVYISWIQNTMWNIPTEGKNFSPSLSSTPLSGLLLFLTSLSSAFLLLGP", "length": 334 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-141212-262", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141212-262#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M9NDV6-1", "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "Dmel\\CG6865", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLKIVFVVAVLSLVKCAQSQIAFSNQPCSVRNPKIVGGSEAERNEMPYMVSLMRRGGHFCGGTIISERWILTAGHCICNGLQQFMKPAQIQGVVGLHSIREYLNGIGNGPDALRVDFKNIVPHPQYDCNDVKHDIALLELVQPIRFSSHIQPSCVGSEEGHRSLEQEYGTVSGWGWTHENQAENDRSDVLRKATVKIWNNEACERSYRSLGKSNTIGETQLCAGYENGQIDSCWADSGGPLMSKEHHLVGVVSTGIGCARPGLPGIYTRVSKYVSWMQKVIDGRK", "length": 285 }, "evidence": [ { "id": "HGNC:29994", "url": "https://alliancegenome.org/gene/HGNC:29994#orthology", "database": "AGR" }, { "id": "HGNC:24465", "url": "https://alliancegenome.org/gene/HGNC:24465#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "O15393-1", "protein_name": "Transmembrane protease serine 2", "gene_name": "TMPRSS2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKNNFYSSQGIVDDSGSTSFMKLNTSAGNVDIYKKLYHSDACSSKAVVSLRCIACGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEKPLNNPWHWTAFAGILRQSFMFYGAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRYVYDNLITPAMICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWIYRQMRADG", "length": 492 }, "evidence": [ { "id": "RGD:620766", "url": "https://alliancegenome.org/gene/RGD:620766#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P13582-1", "protein_name": "Serine protease ea", "gene_name": "ea", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLKPSIICLFLGILAKSSAGQFYFPNEAAQVPNYGRCITPNRERALCIHLEDCKYLYGLLTTTPLRDTDRLYLSRSQCGYTNGKVLICCPDRYRESSSETTPPPKPNVTSNSLLPLPGQCGNILSNRIYGGMKTKIDEFPWMALIEYTKSQGKKGHHCGGSLISTRYVITASHCVNGKALPTDWRLSGVRLGEWDTNTNPDCEVDVRGMKDCAPPHLDVPVERTIPHPDYIPASKNQVNDIALLRLAQQVEYTDFVRPICLPLDVNLRSATFDGITMDVAGWGKTEQLSASNLKLKAAVEGSRMDECQNVYSSQDILLEDTQMCAGGKEGVDSCRGDSGGPLIGLDTNKVNTYYFLAGVVSFGPTPCGLAGWPGVYTLVGKYVDWIQNTIES", "length": 392 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-051127-11", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-051127-11#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P20231-1", "protein_name": "Tryptase beta-2", "gene_name": "TPSB2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLNLLLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVPKKP", "length": 275 }, "evidence": [ { "id": "HGNC:14120", "url": "https://alliancegenome.org/gene/HGNC:14120#orthology", "database": "AGR" }, { "id": "MGI:96943", "url": "https://alliancegenome.org/gene/MGI:96943#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141212-262", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141212-262#orthology", "database": "AGR" }, { "id": "FB:FBgn0036436", "url": "https://alliancegenome.org/gene/FB:FBgn0036436#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P21845-1", "protein_name": "Tryptase beta-2", "gene_name": "Tpsb2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLKRRLLLLWALSLLASLVYSAPRPANQRVGIVGGHEASESKWPWQVSLRFKLNYWIHFCGGSLIHPQWVLTAAHCVGPHIKSPQLFRVQLREQYLYYGDQLLSLNRIVVHPHYYTAEGGADVALLELEVPVNVSTHIHPISLPPASETFPPGTSCWVTGWGDIDNDEPLPPPYPLKQVKVPIVENSLCDRKYHTGLYTGDDFPIVHDGMLCAGNTRRDSCQGDSGGPLVCKVKGTWLQAGVVSWGEGCAQPNKPGIYTRVTYYLDWIHRYVPEHS", "length": 276 }, "evidence": [ { "id": "HGNC:14120", "url": "https://alliancegenome.org/gene/HGNC:14120#orthology", "database": "AGR" }, { "id": "HGNC:12019", "url": "https://alliancegenome.org/gene/HGNC:12019#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141212-262", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141212-262#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P27435-1", "protein_name": "Tryptase", "gene_name": "Tpsab1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLKLLLLTLPLLSSLVHAAPSLAMPREGIVGGQEASGNKWPWQVSLRVNDTYWMHFCGGSLIHPQWVLTAAHCVGPNKADPNKLRVQLRKQYLYYHDHLLTVSQIISHPDFYIAQDGADIALLKLTNPVNITSNVHTVSLPPASETFPSGTLCWVTGWGNINNDVSLPPPFPLEEVQVPIVENRLCDLKYHKGLNTGDNVHIVRDDMLCAGNEGHDSCQGDSGGPLVCKVEDTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIYRYVPKYF", "length": 273 }, "evidence": [ { "id": "HGNC:14118", "url": "https://alliancegenome.org/gene/HGNC:14118#orthology", "database": "AGR" }, { "id": "HGNC:12019", "url": "https://alliancegenome.org/gene/HGNC:12019#orthology", "database": "AGR" }, { "id": "MGI:96943", "url": "https://alliancegenome.org/gene/MGI:96943#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141212-262", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141212-262#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P50343-1", "protein_name": "Tryptase beta-2", "gene_name": "Tpsb2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLKLLLLLALSPLASLVHAAPCPVKQRVGIVGGREASESKWPWQVSLRFKFSFWMHFCGGSLIHPQWVLTAAHCVGLHIKSPELFRVQLREQYLYYADQLLTVNRTVVHPHYYTVEDGADIALLELEIPVNVSTHIHPISLPPASETFPSGTSCWVTGWGDIDSDEPLLPPYPLKQVKVPIVENSLCDRKYHTGLYTGDDVPIVQDGMLCAGNTRSDSCQGDSGGPLVCKVKGTWLQAGVVSWGEGCAEANRPGIYTRVTYYLDWIHRYVPQRS", "length": 274 }, "evidence": [ { "id": "HGNC:14120", "url": "https://alliancegenome.org/gene/HGNC:14120#orthology", "database": "AGR" }, { "id": "HGNC:12019", "url": "https://alliancegenome.org/gene/HGNC:12019#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141212-262", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141212-262#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P57727-1", "protein_name": "Transmembrane protease serine 3", "gene_name": "TMPRSS3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGENDPPAVEAPFSFRSLFGLDDLKISPVAPDADAVAAQILSLLPLKFFPIIVIGIIALILALAIGLGIHFDCSGKYRCRSSFKCIELIARCDGVSDCKDGEDEYRCVRVGGQNAVLQVFTAASWKTMCSDDWKGHYANVACAQLGFPSYVSSDNLRVSSLEGQFREEFVSIDHLLPDDKVTALHHSVYVREGCASGHVVTLQCTACGHRRGYSSRIVGGNMSLLSQWPWQASLQFQGYHLCGGSVITPLWIITAAHCVYDLYLPKSWTIQVGLVSLLDNPAPSHLVEKIVYHSKYKPKRLGNDIALMKLAGPLTFNEMIQPVCLPNSEENFPDGKVCWTSGWGATEDGAGDASPVLNHAAVPLISNKICNHRDVYGGIISPSMLCAGYLTGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRVTSFLDWIHEQMERDLKT", "length": 454 }, "evidence": [ { "id": "RGD:1310135", "url": "https://alliancegenome.org/gene/RGD:1310135#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P83748-1", "protein_name": "Serine protease 30", "gene_name": "Prss30", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESWARCIFLLLLQILTGGRGDILHSGAGKIVGGQDAPEGRWPWQVSLRTEKEGHICGGSLIHEVWVLTAAHCFRRPLNSSFYHVKVGGLTLSLTEPHSTLVAVRNIFVYPTYLWEDASSGDIALLRLDTPLQPSQFSPVCLPQAQAPLTPGTVCWVTGWGATHERELASVLQELAVPLLDSEDCERMYHIGETSLSGKRVIQSDMLCAGFVEGQKDSCQGDSGGPLVCAINSSWIQVGITSWGIGCARPNKPGVYTRVPDYVDWIQRTLAENHSDAYGCRSRASGAYPALLLVLLAFALPESL", "length": 304 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-141212-262", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141212-262#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q02844-1", "protein_name": "Tryptase", "gene_name": "Tpsab1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLKLLLLTLPLLSSLVHAAPGPAMTREGIVGGQEAHGNKWPWQVSLRANDTYWMHFCGGSLIHPQWVLTAAHCVGPDVADPNKVRVQLRKQYLYYHDHLMTVSQIITHPDFYIVQDGADIALLKLTNPVNISDYVHPVPLPPASETFPSGTLCWVTGWGNIDNGVNLPPPFPLKEVQVPIIENHLCDLKYHKGLITGDNVHIVRDDMLCAGNEGHDSCQGDSGGPLVCKVEDTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVPKDF", "length": 273 }, "evidence": [ { "id": "HGNC:14118", "url": "https://alliancegenome.org/gene/HGNC:14118#orthology", "database": "AGR" }, { "id": "HGNC:14120", "url": "https://alliancegenome.org/gene/HGNC:14120#orthology", "database": "AGR" }, { "id": "HGNC:12019", "url": "https://alliancegenome.org/gene/HGNC:12019#orthology", "database": "AGR" }, { "id": "MGI:96943", "url": "https://alliancegenome.org/gene/MGI:96943#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141212-262", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141212-262#orthology", "database": "AGR" }, { "id": "FB:FBgn0036436", "url": "https://alliancegenome.org/gene/FB:FBgn0036436#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q14C59-1", "protein_name": "Transmembrane protease serine 11B-like protein", "gene_name": "Tmprss11b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MYRPVIASRKSIPPWLIILCVLGVLAALGIIIGLLVHFLAVENKIYYYQGGFKVLDIPYDRNYERETSLESNYLSKILENKMVEAFQNSNIYKQYINSQVITLVPDNNSVTAHIWLVFKDPWSNKENLRRRIESILRQMLENNPESLTTDPGSLKLTEISKVDAEKIINNRCGRRPRMSATYDRITGGSTAHKGEWPWQASLRVNGKHYCGASLIGERFLLTAAHCFQGTNNPKNLTVSFGTRVTPAYMQHSVQEIIIHEDYVKGEHHDDVAVIKLTEKVSFNNDVHRVCLPESTQIFPPGEGVVVTGWGSFSYNGKSPLLLQKASIKIIDTNTCNSEEAYGGRIVDTMLCAGYLEGSIDACQGDSGGPLVHPNSRDIWYLVGIVSWGHECGRVNKPGVYMRVTSYRNWIASKTGI", "length": 416 }, "evidence": [ { "id": "HGNC:25398", "url": "https://alliancegenome.org/gene/HGNC:25398#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q15661-1", "protein_name": "Tryptase alpha/beta-1", "gene_name": "TPSAB1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLNLLLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVPKKP", "length": 275 }, "evidence": [ { "id": "HGNC:12019", "url": "https://alliancegenome.org/gene/HGNC:12019#orthology", "database": "AGR" }, { "id": "MGI:96943", "url": "https://alliancegenome.org/gene/MGI:96943#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141212-262", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141212-262#orthology", "database": "AGR" }, { "id": "FB:FBgn0036436", "url": "https://alliancegenome.org/gene/FB:FBgn0036436#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q1JRP2-1", "protein_name": "Transmembrane protease serine 11C", "gene_name": "Tmprss11c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARGQPRRSEEQWTALQNRTECKTKIKLTRCGKITLGILTAVLAAVLIGLIAYFAACGKDSFYYHVSFKVNNIDYDSKFAKPYSQEYMDLNKRIVSLMNETFHESKLRKQYVKAHTVQVSKAKGKVVIHAVLKFKACYRNNVEKYWESVETTLYQKLKGQTGLLIDSSSFKFSDIAMPIAEDLLNTCCGRRTIIHRGHKVAGGQDAEEGEWPWQASLQQNSVHRCGATLISNYWLITAAHCFIRAANPKDWKVSFGFLLSKPQAPRAVKNIIIHENYSYPAHDNDIAVVRLSSPVLYESNIRRACLPEATQKFPPNSDVVVTGWGTLKSDGDSPNILQKGKVKIIDNKTCNSGKAYGGMITPGMMCAGFLKGRVDACQGDSGGPLVSEDSKGIWFLAGIVSWGDECALPNKPGVYTRVTYYRDWITSKTGL", "length": 431 }, "evidence": [ { "id": "MGI:3521861", "url": "https://alliancegenome.org/gene/MGI:3521861#orthology", "database": "AGR" }, { "id": "FB:FBgn0036436", "url": "https://alliancegenome.org/gene/FB:FBgn0036436#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5S248-1", "protein_name": "Transmembrane protease serine 11E", "gene_name": "Tmprss11e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MYRSCVVRARKRTCVEPWVIGIISFLSLIVLAVCIGLTVHYVRYNHRRTYNYYSTLSFTSDKLYSEFGREASKNFTEMSQRIETMVKHAFHKSPLRGQLVKAHIIKFSKEDDGVLAHMLLIFRIRSTEDPETVHKIIEYVLHEKLKYATGPPNVDPESVKIKKINKTESDNYFNHCCGTRRNKSTVQTSVRIVGGTPVEEEEWPWQSSLRWDGSHRCGATLINNTWLVTAAHCFRTHKDPSRWSATFGATLQPRKLTTGIRRIIVHEKYKYPSHDYDIALAELSKPVPCTNAVHKVCLPDANHEFQPGQRMFVTGFGALKNDGFTQNNLRQVQVDYIDTQTCNQPQSYNGAITPRMLCAGFLKGEKDACQGDSGGPLVTADVRDIWYLAGVVSWGDECGQPNKPGVYTRVTAFRHWIASNTGI", "length": 423 }, "evidence": [ { "id": "HGNC:24465", "url": "https://alliancegenome.org/gene/HGNC:24465#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6BEA2-1", "protein_name": "Serine protease 27", "gene_name": "Prss27", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRQPHITALLLLPLLLRSGTEGAEAMRACGHPRMFNRMVGGEDALEGEWPWQVSIQRNGAHFCGGSLIAPTWVLTAAHCFSNTSDISIYQVLLGALKLQQPGPHALYVPVKRVKSHPEYQGMASSADVALVELQVPVTFTKYILPVCLPDPSVVFKSGMNCWVTGWGSPSEQDRLPNPRILQKLAVPLIDTPKCNLLYSKDAEADIQLKTIKDDMLCAGFAEGKKDACKGDSGGPLVCLVDQSWVQAGVISWGEGCARRNRPGVYIRVASHYQWIHQIIPELQFQGRAGSQQQQRDPRGWQPLAENSAPCLAAHAVLLALGALMLGIL", "length": 328 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-141212-262", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141212-262#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6IE14-1", "protein_name": "Transmembrane protease serine 11B-like protein", "gene_name": "Tmprss11bnl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVSKLRPVIASRKSFPPWMIILGVLGVLAILGLIIGLLVHFLAVENKIYYYQGSFKVLNIPYDRNYERETSLESNYLSKILEIKMVDAFESSNIYKQYINSQIITLVPENNSVTAHIWLVFKDPWSNKENLRRRIESILHQMLENNSGSLTTDPGSLKLTEITKVDAEKIINNRCGRRPRMSATYDRITGGSTAQKGEWPWQASLRVNGKHHCGASLIGERFLLTAAHCFLRTNNPKNLTVSFGTRVTPAYMQHYVEEVIIHEDYVKGQHHDDVAIIKLTEKVSFRNDVHRVCLPEATQVFPPGEGVVVTGWGSLSYNGKSPLLLQKASIKIIDTNACNSEEAYGGRIMDTMLCAGYMEGYVDACQGDSGGPLVHPNSRDIWYLVGIVSWGHECGRVNKPGVYMRVTSYRDWIASKTGI", "length": 420 }, "evidence": [ { "id": "HGNC:25398", "url": "https://alliancegenome.org/gene/HGNC:25398#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6P7D7-1", "protein_name": "Transmembrane protease serine 2", "gene_name": "Tmprss2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALNSGSPPGIGPYYENHGYQSEHVYSPRPPVSPSGYNLYPAQSCPSPVPQYAPRVTTQASTPAIHIQPRSSGTLCTSKSKKSMLVALALGTVLAGAAVAAGLLWKFWDSKCSSSEMECGSSGTCISSSLWCDGVSQCPNGEDENRCVRLYGTSFTLQVYSSQRKAWYPVCQDDWNESYGRAACKDMGYKNSFYSSQGIPDQSGATSFMKLNVSAGNVDLYKKLYHSDSCSSRMVVSLRCIECGVRSVRRQSRIVGGSTASPGDWPWQVSLHVQGIHVCGGSIITPEWIVTAAHCVEEPLSSPRYWTAFAGILKQSLMFYGSRHQVEKVISHPNYDSKTKNNDIALMKLQTPLAFNDVVKPVCLPNPGMMLDLAQECWISGWGATYEKGKTSDVLNAAMVPLIEPSKCNSKYIYNNLITPAMICAGFLQGSVDSCQGDSGGPLVTLKNEIWWLIGDTSWGSGCAKAYRPGVYGNVTVFTDWIYQQMRANS", "length": 490 }, "evidence": [ { "id": "RGD:620766", "url": "https://alliancegenome.org/gene/RGD:620766#orthology", "database": "AGR" }, { "id": "FB:FBgn0036436", "url": "https://alliancegenome.org/gene/FB:FBgn0036436#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6ZWK6-1", "protein_name": "Transmembrane protease serine 11F", "gene_name": "TMPRSS11F", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMYAPVEFSEAEFSRAEYQRKQQFWDSVRLALFTLAIVAIIGIAIGIVTHFVVEDDKSFYYLASFKVTNIKYKENYGIRSSREFIERSHQIERMMSRIFRHSSVGGRFIKSHVIKLSPDEQGVDILIVLIFRYPSTDSAEQIKKKIEKALYQSLKTKQLSLTINKPSFRLTPIDSKKMRNLLNSRCGIRMTSSNMPLPASSSTQRIVQGRETAMEGEWPWQASLQLIGSGHQCGASLISNTWLLTAAHCFWKNKDPTQWIATFGATITPPAVKRNVRKIILHENYHRETNENDIALVQLSTGVEFSNIVQRVCLPDSSIKLPPKTSVFVTGFGSIVDDGPIQNTLRQARVETISTDVCNRKDVYDGLITPGMLCAGFMEGKIDACKGDSGGPLVYDNHDIWYIVGIVSWGQSCALPKKPGVYTRVTKYRDWIASKTGM", "length": 438 }, "evidence": [ { "id": "HGNC:29994", "url": "https://alliancegenome.org/gene/HGNC:29994#orthology", "database": "AGR" }, { "id": "FB:FBgn0036436", "url": "https://alliancegenome.org/gene/FB:FBgn0036436#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7KT71-1", "protein_name": "Phenoloxidase-activating factor 2", "gene_name": "Dmel\\CG31827", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFEAWTLIVALFVLGVAENVENLQQIEELKCGYGNPDAVKVQFNVTEGQAKPAEFPWTIAVIHNRSLVGGGSLITPDIVLTAAHRIFNKDVEDIVVSAGEWEYGSALEKYPFEEAFVLKMVIHKSFNYQRGANNLALLFLDREFPLTYKINTICLPTQKRSLSSTRCIVAGWGKYQFSDTHYGGVLKKIDLPIVPRHICQDQLRKTRLGQNYTLPRGLICAGGEKDNDACTGDGGGALFCPMTEDPKQFEQIGIVNWGVGCKEKNVPATYTDVFEFKPWIVQQIKENLYTPDNY", "length": 294 }, "evidence": [ { "id": "MGI:96943", "url": "https://alliancegenome.org/gene/MGI:96943#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q7KT73-1", "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "Dmel\\CG18477", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDSMYGIIAIVSLILVAGQVQAQGQNAELNQSCGASNEHQCVPRHMCKVKIEFRMAMTYRNLGCVSTAICCPKNLIIKEPRLIINEPITDPQCGFVNSKGVTFSFREEDTGLAQEAEVPWMVALLDARTSSYVAGGALIAPHVVITARQRTENMTASQLVVRAGEWDFSTKTEQLPSVDVPIRSIVRHPGFNLENGANNVALVFLRRSLTSSRHINPICMPSAPKNFDFSRCIFTGWGKNSFDDPSYMNVLKKISLPVVQRRTCEQQLRLYYGNDFELDNSLMCAGGEPGKDSCEGDGGSPLACAIKDNPQRYELAGIVNFGVDCGLPGVPAVYTNVANVIEWITLTTVNMPLPEEREEVPYASPTLSAGPYLNQWNQPNYEWLPTGYPNVNSIPWQLQEANNDLANSQYVRYYPVENVGINIHSAGHGNDQQIVRPIQQDIPKDSDDLFNSVFSTTMEYNFDA", "length": 464 }, "evidence": [ { "id": "HGNC:14134", "url": "https://alliancegenome.org/gene/HGNC:14134#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q7KVM3-1", "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "SP20", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKLPWILIALFCGLCSGSTERRIRPNEGKIFEWLGSILLPSTTTTTSTPVVATTSTTTRRTTTTSSTTSRTTTSRTTVANFPIERDCVTCRCGLINTLYKIVGGQETRVHQYPWMAVILIYNRFYCSGSLINDLYVLTAAHCVEGVPPELITLRFLEHNRSHSNDDIVIQRYVSRVKVHELYNPRSFDNDLAVLRLNQPLDMRHHRLRPICLPVQSYSFDHELGIVAGWGAQREGGFGTDTLREVDVVVLPQSECRNGTTYRPGQITDNMMCAGYISEGGKDACSGDSGGPLQTTFDEQPGQYQLAGIVSWGVGCARPQSPGVYTRVNQYLRWLGSNTPGGCHCMPYPEEDY", "length": 352 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-051127-11", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-051127-11#orthology", "database": "AGR" }, { "id": "HGNC:14118", "url": "https://alliancegenome.org/gene/HGNC:14118#orthology", "database": "AGR" }, { "id": "HGNC:14120", "url": "https://alliancegenome.org/gene/HGNC:14120#orthology", "database": "AGR" }, { "id": "HGNC:12019", "url": "https://alliancegenome.org/gene/HGNC:12019#orthology", "database": "AGR" }, { "id": "HGNC:14134", "url": "https://alliancegenome.org/gene/HGNC:14134#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141212-262", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141212-262#orthology", "database": "AGR" }, { "id": "RGD:620766", "url": "https://alliancegenome.org/gene/RGD:620766#orthology", "database": "AGR" }, { "id": "RGD:1310135", "url": "https://alliancegenome.org/gene/RGD:1310135#orthology", "database": "AGR" }, { "id": "RGD:628625", "url": "https://alliancegenome.org/gene/RGD:628625#orthology", "database": "AGR" }, { "id": "MGI:3521861", "url": "https://alliancegenome.org/gene/MGI:3521861#orthology", "database": "AGR" }, { "id": "HGNC:29994", "url": "https://alliancegenome.org/gene/HGNC:29994#orthology", "database": "AGR" }, { "id": "HGNC:24465", "url": "https://alliancegenome.org/gene/HGNC:24465#orthology", "database": "AGR" }, { "id": "HGNC:25398", "url": "https://alliancegenome.org/gene/HGNC:25398#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q7KVM8-1", "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "Dmel\\CG33226", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAHSLIEFKMKWLLVCFILALRSYESLGQDLLDPNCVQTPVGVREQILGGHNADIKLHPWMVQILQRGYHFCGGSLISSLFVLTAAHCHSRYRLKVRFGRYSGITPRYLCSSQYCSPFGPEIDVKRIFLHSSYRDYHNYDIALFLLAKPVRYNVQTRPICVLQTSNKDKLRQFLNYVAMFNVTGWGKTESQLTSTILQTTSLFHLDRKFCAQIFDRKIGWPHICAGHSQSSTCTGDSGGPLSAELTFSGVKRTVLFGIISYGAPNCREVTVFTNVLRYSNWIRDIVHNFTPS", "length": 292 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-051127-11", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-051127-11#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q86T26-1", "protein_name": "Transmembrane protease serine 11B", "gene_name": "TMPRSS11B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MYRHGISSQRSWPLWTTIFIFLGVAAILGVTIGLLVHFLAVEKTYYYQGDFHISGVTYNDNCENAASQASTNLSKDIETKMLNAFQNSSIYKEYVKSEVIKLLPNANGSNVQLQLKFKFPPAEGVSMRTKIKAKLHQMLKNNMASWNAVPASIKLMEISKAASEMLTNNCCGRQVANSIITGNKIVNGKSSLEGAWPWQASMQWKGRHYCGASLISSRWLLSAAHCFAKKNNSKDWTVNFGIVVNKPYMTRKVQNIIFHENYSSPGLHDDIALVQLAEEVSFTEYIRKICLPEAKMKLSENDNVVVTGWGTLYMNGSFPVILQEDFLKIIDNKICNASYAYSGFVTDTMLCAGFMSGEADACQNDSGGPLAYPDSRNIWHLVGIVSWGDGCGKKNKPGVYTRVTSYRNWITSKTGL", "length": 416 }, "evidence": [ { "id": "HGNC:25398", "url": "https://alliancegenome.org/gene/HGNC:25398#orthology", "database": "AGR" }, { "id": "FB:FBgn0036436", "url": "https://alliancegenome.org/gene/FB:FBgn0036436#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BHM9-1", "protein_name": "Transmembrane protease serine 11F", "gene_name": "Tmprss11f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMYAPVEFSQTAYPRIEYQRRQQQFWDPIRLALFTLAIVAIVGITIGIVTHFVVEDDKSFYYLASFQVTSIKYRENYGIRSSREFIERSHQIERMMSRIFRRSSGVGRFIKSHVIKISPDEQGVNILIVLMFRYPSTDSAERIKKRIERTFYQSLKIKQLPLTISMPSFSLTPIDSKKMRNLLNSRCGIRMSSSNIPLPASSSTERIVQGRETAMEGEWPWQASLQLIGAGHQCGATLISNTWLLTAAHCFWKNRDPTKWIVTFGTTITPPLVKRSVGKIIIHEEYHRDTNENDIALAQLTTRVEFSNVVQRVCLPDSSMKLPPKTSVFVTGFGSIVDDGPTQNKLRQARVETIGSDVCNRKDVYDGLITPGMLCAGFMEGKIDACKGDSGGPLVYDNRDIWYIVGIVSWGQSCALPNKPGVYTRVTKYRDWIASKTGL", "length": 439 }, "evidence": [ { "id": "HGNC:29994", "url": "https://alliancegenome.org/gene/HGNC:29994#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8BJR6-1", "protein_name": "Serine protease 27", "gene_name": "Prss27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRQPHIAALLLLPLLLRSGTEGARTLRACGHPKMFNRMVGGENALEGEWPWQVSIQRNGIHFCGGSLIAPTWVLTAAHCFSNTSDISIYQVLLGALKLQQPGPHALYVPVKQVKSNPQYQGMASSADVALVELQGPVTFTNYILPVCLPDPSVIFESGMNCWVTGWGSPSEQDRLPNPRVLQKLAVPIIDTPKCNLLYNKDVESDFQLKTIKDDMLCAGFAEGKKDACKGDSGGPLVCLVDQSWVQAGVISWGEGCARRNRPGVYIRVTSHHKWIHQIIPELQFQGRAGTQQQQKDSQGQQRLAGNSAPCLAAHAMVLALGALLLRIV", "length": 328 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-141212-262", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141212-262#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IP30-1", "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "SPH208", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDRLSILLLVLGFSRIQALFCGGSMAKECVQRNRCRIGTETGRPIIDFRGLNNGNQGCESGQTCCPKTEILQYPVQADNQPLPTECGHVNRIGVGFTITNARDIAQKGELPWMVALLDSRSRLPLGGGSLITRDVVLTSSTKTLEVPEKYLIVRAGEWDFESITEERAHEDVAIRKIVRHTNLSVENGANNAALLFLARPLKLDHHIGLICLPPPNRNFIHNRCIVSGWGKKTALDNSYMNILKKIELPLVDRSVCQTKLQGPYGKDFILDNSLICAGGEPGKDTCKGDGGAPLACPLQSDPNRYELLGIVNFGFGCGGPLPAAYTDVSQIRSWIDNCIQAEAVHYSPQLGNVGQSPAPLDRYIPNIGLETQNEVHSPVQGSLHNVVYQTGGVGYIRGMGQGTAFQGPVQVGELIPNEGTVSGGLVYDSNEIQKFNQGGIYIPHVGQGNSDNRYYPNPEIGAVPVGNPIPNEGNAFGGRGYDFNEIQKHNQGGRYIPHVGHGNGPNAPKEPLKIGGNIPNVGQGNRGNRYDLNPEIGAVPVGNPIPNEGNAFGGRGYDLNEIQKHNQGGRYIPHVGHGNGPNAPKELLKIGGNIPNVGQGNRGNIYDPNPEIGAVPVGNPIPNEGNAFGGRGYDLNEIQKHNQGGRYIPHVGHGNGPNAPKEPLKIGGNIPNVGQGNRGNIYDPNPEIGAVPVGNPIPNEGNAFGGRGYDLNEIQKHNQGGRYIPHVGHGNGPNAPKEPLKIGGNIPNVGQGNRGNRYDPNPEIGAVPVGNPIPNEGNAFGGRGYDLNEIQKHNQGGRYIPHVGHGNGPNAPKEPLKIGGNIPNVGQGNRGNRYDLNPEIGHATFGATGTGMQGNNIDNPYKNNLGDRAENELERFPLENPNRDHVIRLSDFLITTPTPSAPIKLVIEKI", "length": 910 }, "evidence": [ { "id": "HGNC:14118", "url": "https://alliancegenome.org/gene/HGNC:14118#orthology", "database": "AGR" }, { "id": "HGNC:14120", "url": "https://alliancegenome.org/gene/HGNC:14120#orthology", "database": "AGR" }, { "id": "HGNC:12019", "url": "https://alliancegenome.org/gene/HGNC:12019#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8K1T0-1", "protein_name": "Transmembrane protease serine 3", "gene_name": "Tmprss3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGENDPPAAEAPFSFRSLFGLDDLKISPVAPDGDAVAAQILSLLPLKFFPIIVIGIIALILALAIGLGIHFDCSGKYRCHSSFKCIELTARCDGVSDCKNAEDEYRCVRVSGQRAALQVFTAAAWRTMCSDDWKSHYAKIACAQLGFPSYVSSDHLRVDALEEQFQGDFVSINHLLSDDKVTALHHSVYMREGCTSGHVVTLKCSACGTRTGYSPRIVGGNMSSLTQWPWQVSLQFQGYHLCGGSIITPLWIVTAAHCVYDLYHPKSWTVQVGLVSLMDSPVPSHLVEKIIYHSKYKPKRLGNDIALMKLSEPLTFDETIQPICLPNSEENFPDGKLCWTSGWGATEDGGDASPVLNHAAVPLISNKICNHRDVYGGIISPSMLCAGYLKGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRITSFLDWIHEQLERDLKT", "length": 453 }, "evidence": [ { "id": "RGD:1310135", "url": "https://alliancegenome.org/gene/RGD:1310135#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NF86-1", "protein_name": "Serine protease 33", "gene_name": "PRSS33", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRGVSCLQVLLLLVLGAAGTQGRKSAACGQPRMSSRIVGGRDGRDGEWPWQASIQHRGAHVCGGSLIAPQWVLTAAHCFPRRALPAEYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSEDGARGDLALLQLRRPVPLSARVQPVCLPVPGARPPPGTPCRVTGWGSLRPGVPLPEWRPLQGVRVPLLDSRTCDGLYHVGADVPQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQSGSWVLVGVVSWGKGCALPNRPGVYTSVATYSPWIQARVSF", "length": 280 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-141212-262", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141212-262#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99MS4-1", "protein_name": "Serine protease 29", "gene_name": "Prss29", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLIQLCLTLFFLGCSIAGTPAPGPEDVLMGIVGGHSAPQGKWPWQVSLRIYRYYWAFWVHNCGGSIIHPQWVLTAAHCIRERDADPSVFRIRVGEAYLYGGKELLSVSRVIIHPDFVHAGLGSDVALLQLAVSVQSFPNVKPVKLPSESLEVTKKDVCWVTGWGAVSTHRSLPPPYRLQQVQVKIIDNSLCEEMYHNATRHRNRGQKLILKDMLCAGNQGQDSCYGDSGGPLVCNVTGSWTLVGVVSWGYGCALRDFPGVYARVQSFLPWITQQMQRFS", "length": 279 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-051127-11", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-051127-11#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BQR3-1", "protein_name": "Serine protease 27", "gene_name": "PRSS27", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRRPAAVPLLLLLCFGSQRAKAATACGRPRMLNRMVGGQDTQEGEWPWQVSIQRNGSHFCGGSLIAEQWVLTAAHCFRNTSETSLYQVLLGARQLVQPGPHAMYARVRQVESNPLYQGTASSADVALVELEAPVPFTNYILPVCLPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQKLAVPIIDTPKCNLLYSKDTEFGYQPKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQSWLQAGVISWGEGCARQNRPGVYIRVTAHHNWIHRIIPKLQFQPARLGGQK", "length": 290 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-141212-262", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141212-262#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9BZJ3-1", "protein_name": "Tryptase delta", "gene_name": "TPSD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLLLAPQMLSLLLLALPVLASPAYVAPAPGQALQQTGIVGGQEAPRSKWPWQVSLRVRGPYWMHFCGGSLIHPQWVLTAAHCVEPDIKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYIIQTGADIALLELEEPVNISSHIHTVTLPPASETFPPGMPCWVTGWGDVDNNVHLPPPYPLKEVEVPVVENHLCNAEYHTGLHTGHSFQIVRDDMLCAGSENHDSCQGDSGGPLVCKVNGT", "length": 242 }, "evidence": [ { "id": "HGNC:14118", "url": "https://alliancegenome.org/gene/HGNC:14118#orthology", "database": "AGR" }, { "id": "MGI:96943", "url": "https://alliancegenome.org/gene/MGI:96943#orthology", "database": "AGR" }, { "id": "FB:FBgn0036436", "url": "https://alliancegenome.org/gene/FB:FBgn0036436#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9ER04-1", "protein_name": "Transmembrane protease serine 5", "gene_name": "Tmprss5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSPTLDDQSPMEIRCTEEGAGPGIFRMELGDQRQSISQSQRWCCLQRGCVILGVLGLLAGAGIASWLLVLYLWPAASPSISGTLQEEEMTLNCPGVSREEELLPSLPKTVSFRINGEDLLLQVQVRARPDWLLVCHEGWSPALGMHICKSLGHIRLTQHKAVNLSDIKLNRSQEFAQLSARPGGLVEESWKPSANCPSGRIVSLKCSECGARPLASRIVGGQAVASGRWPWQASVMLGSRHTCGASVLAPHWVVTAAHCMYSFRLSRLSSWRVHAGLVSHGAVRQHQGTMVEKIIPHPLYSAQNHDYDVALLQLRTPINFSDTVGAVCLPAKEQHFPWGSQCWVSGWGHTDPSHTHSSDTLQDTMVPLLSTYLCNSSCMYSGALTHRMLCAGYLDGRADACQGDSGGPLVCPSGDTWHLVGVVSWGRGCAEPNRPGVYAKVAEFLDWIHDTVQVR", "length": 455 }, "evidence": [ { "id": "RGD:628625", "url": "https://alliancegenome.org/gene/RGD:628625#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9GZN4-1", "protein_name": "Brain-specific serine protease 4", "gene_name": "PRSS22", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVSGAPPALGGGCLGTFTSLLLLASTAILNAARIPVPPACGKPQQLNRVVGGEDSTDSEWPWIVSIQKNGTHHCAGSLLTSRWVITAAHCFKDNLNKPYLFSVLLGAWQLGNPGSRSQKVGVAWVEPHPVYSWKEGACADIALVRLERSIQFSERVLPICLPDASIHLPPNTHCWISGWGSIQDGVPLPHPQTLQKLKVPIIDSEVCSHLYWRGAGQGPITEDMLCAGYLEGERDACLGDSGGPLMCQVDGAWLLAGIISWGEGCAERNRPGVYISLSAHRSWVEKIVQGVQLRGRAQGGGALRAPSQGSGAAARS", "length": 317 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-141212-262", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141212-262#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9H3S3-1", "protein_name": "Transmembrane protease serine 5", "gene_name": "TMPRSS5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLMLDDQPPMEAQYAEEGPGPGIFRAEPGDQQHPISQAVCWRSMRRGCAVLGALGLLAGAGVGSWLLVLYLCPAASQPISGTLQDEEITLSCSEASAEEALLPALPKTVSFRINSEDFLLEAQVRDQPRWLLVCHEGWSPALGLQICWSLGHLRLTHHKGVNLTDIKLNSSQEFAQLSPRLGGFLEEAWQPRNNCTSGQVVSLRCSECGARPLASRIVGGQSVAPGRWPWQASVALGFRHTCGGSVLAPRWVVTAAHCMHSFRLARLSSWRVHAGLVSHSAVRPHQGALVERIIPHPLYSAQNHDYDVALLRLQTALNFSDTVGAVCLPAKEQHFPKGSRCWVSGWGHTHPSHTYSSDMLQDTVVPLFSTQLCNSSCVYSGALTPRMLCAGYLDGRADACQGDSGGPLVCPDGDTWRLVGVVSWGRGCAEPNHPGVYAKVAEFLDWIHDTAQDSLL", "length": 457 }, "evidence": [ { "id": "RGD:628625", "url": "https://alliancegenome.org/gene/RGD:628625#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9I7V4-1", "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "SP22", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MCNFHLLLILATALGDLACATPSLRSASDPEKILNNLAQLRQSSFLDWIQSILGPEVPAEWSSPAKRECAECSCGNINTRHRIVGGQETEVHEYPWMIMLMWFGNFYCGASLVNDQYALTAAHCVNGFYHRLITVRLLEHNRQDSHVKIVDRRVSRVLIHPKYSTRNFDSDIALIRFNEPVRLGIDMHPVCMPTPSENYAGQTAVVTGWGALSEGGPISDTLQEVEVPILSQEECRNSNYGESKITDNMICAGYVEQGGKDSCQGDSGGPMHVLGSGDAYQLAGIVSWGEGCAKPNAPGVYTRVGSFNDWIAENTRDACSCAQPEAAGEPASPMETTEQGDQENTTANGAAEADPEVEEANKLI", "length": 364 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-051127-11", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-051127-11#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141212-262", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141212-262#orthology", "database": "AGR" }, { "id": "RGD:620766", "url": "https://alliancegenome.org/gene/RGD:620766#orthology", "database": "AGR" }, { "id": "RGD:1310135", "url": "https://alliancegenome.org/gene/RGD:1310135#orthology", "database": "AGR" }, { "id": "RGD:628625", "url": "https://alliancegenome.org/gene/RGD:628625#orthology", "database": "AGR" }, { "id": "MGI:3521861", "url": "https://alliancegenome.org/gene/MGI:3521861#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9JIQ8-1", "protein_name": "Transmembrane protease serine 2", "gene_name": "Tmprss2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALNSGSPPGIGPCYENHGYQSEHICPPRPPVAPNGYNLYPAQYYPSPVPQYAPRITTQASTSVIHTHPKSSGALCTSKSKKSLCLALALGTVLTGAAVAAVLLWRFWDSNCSTSEMECGSSGTCISSSLWCDGVAHCPNGEDENRCVRLYGQSFILQVYSSQRKAWYPVCQDDWSESYGRAACKDMGYKNNFYSSQGIPDQSGATSFMKLNVSSGNVDLYKKLYHSDSCSSRMVVSLRCIECGVRSVKRQSRIVGGLNASPGDWPWQVSLHVQGVHVCGGSIITPEWIVTAAHCVEEPLSSPRYWTAFAGILRQSLMFYGSRHQVEKVISHPNYDSKTKNNDIALMKLQTPLAFNDLVKPVCLPNPGMMLDLDQECWISGWGATYEKGKTSDVLNAAMVPLIEPSKCNSKYIYNNLITPAMICAGFLQGSVDSCQGDSGGPLVTLKNGIWWLIGDTSWGSGCAKALRPGVYGNVTVFTDWIYQQMRANS", "length": 490 }, "evidence": [ { "id": "RGD:620766", "url": "https://alliancegenome.org/gene/RGD:620766#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NRR2-1", "protein_name": "Tryptase gamma", "gene_name": "TPSG1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALGACGLLLLLAVPGVSLRTLQPGCGRPQVSDAGGRIVGGHAAPAGAWPWQASLRLRRVHVCGGSLLSPQWVLTAAHCFSGSLNSSDYQVHLGELEITLSPHFSTVRQIILHSSPSGQPGTSGDIALVELSVPVTLSSRILPVCLPEASDDFCPGIRCWVTGWGYTREGEPLPPPYSLREVKVSVVDTETCRRDYPGPGGSILQPDMLCARGPGDACQDDSGGPLVCQVNGAWVQAGTVSWGEGCGRPNRPGVYTRVPAYVNWIRRHITASGGSESGYPRLPLLAGFFLPGLFLLLVSCVLLAKCLLHPSADGTPFPAPD", "length": 321 }, "evidence": [ { "id": "HGNC:14134", "url": "https://alliancegenome.org/gene/HGNC:14134#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141212-262", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141212-262#orthology", "database": "AGR" }, { "id": "FB:FBgn0036436", "url": "https://alliancegenome.org/gene/FB:FBgn0036436#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QUL7-1", "protein_name": "Tryptase gamma", "gene_name": "Tpsg1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGPNCGILLFLAVSGCGHPQVSNSGSRIVGGHAAPAGTWPWQASLRLHKVHVCGGSLLSPEWVLTAAHCFSGSVNSSDYQVHLGELTVTLSPHFSTVKRIIMYTGSPGPPGSSGDIALVQLSSPVALSSQVQPVCLPEASADFYPGMQCWVTGWGYTGEGEPLKPPYNLQEAKVSVVDVKTCSQAYNSPNGSLIQPDMLCARGPGDACQDDSGGPLVCQVAGTWQQAGVVSWGEGCGRPDRPGVYARVTAYVNWIHHHIPEAGGSGMQGLPWAPLLAALFWPSLFLLLVSGVLMAKYWLSSPSHAASEL", "length": 311 }, "evidence": [ { "id": "HGNC:14134", "url": "https://alliancegenome.org/gene/HGNC:14134#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141212-262", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141212-262#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9QYZ9-1", "protein_name": "Serine protease 30", "gene_name": "Prss30", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESRARCIFLLLLQILTRARGDILPSVCGHSRDAGKIVGGQDALEGQWPWQVSLWITEDGHICGGSLIHEVWVLTAAHCFRRSLNPSFYHVKVGGLTLSLLEPHSTLVAVRNIFVHPTYLWADASSGDIALVQLDTPLRPSQFTPVCLPAAQTPLTPGTVCWVTGWGATQERDMASVLQELAVPLLDSEDCEKMYHTQGSSLSGERIIQSDMLCAGYVEGQKDSCQGDSGGPLVCSINSSWTQVGITSWGIGCARPYRPGVYTRVPTYVDWIQRILAENHSDAYGYHSSASAAYQMLLPVLLAVALPGSL", "length": 310 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-141212-262", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141212-262#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UL52-1", "protein_name": "Transmembrane protease serine 11E", "gene_name": "TMPRSS11E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMYRPDVVRARKRVCWEPWVIGLVIFISLIVLAVCIGLTVHYVRYNQKKTYNYYSTLSFTTDKLYAEFGREASNNFTEMSQRLESMVKNAFYKSPLREEFVKSQVIKFSQQKHGVLAHMLLICRFHSTEDPETVDKIVQLVLHEKLQDAVGPPKVDPHSVKIKKINKTETDSYLNHCCGTRRSKTLGQSLRIVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCFTTYKNPARWTASFGVTIKPSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDASYEFQPGDVMFVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQAYNDAITPRMLCAGSLEGKTDACQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKPGVYTRVTALRDWITSKTGI", "length": 423 }, "evidence": [ { "id": "HGNC:24465", "url": "https://alliancegenome.org/gene/HGNC:24465#orthology", "database": "AGR" }, { "id": "FB:FBgn0036436", "url": "https://alliancegenome.org/gene/FB:FBgn0036436#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9V3Z2-1", "protein_name": "Serine protease 7", "gene_name": "Sp7", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKSTRKVVGIFLATCLLPFTVLQNVAAQGSCRNPNQKQGQCLSIYDCQSLLSVIQQSYVSPEDRTFLRNSQCLDGVGRQPYVCCTSDRSFGSQEATSAAPPPTTTSSSSRGQDGQAGLGNLLPSPPKCGPHSFSNKVYNGNDTAIDEFNWMALLEYVDNRGRRELSCGGSLINNRYVLTAAHCVIGAVETEVGHLTTVRLGEYDTSKDVDCIDDICNQPILQLGIEQATVHPQYDPANKNRIHDIALLRLDRPVVLNEYIQPVCLPLVSTRMAINTGELLVVSGWGRTTTARKSTIKQRLDLPVNDHDYCARKFATRNIHLISSQLCVGGEFYRDSCDGDSGGPLMRRGFDQAWYQEGVVSFGNRCGLEGWPGVYTRVADYMDWIVETIRP", "length": 391 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-051127-11", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-051127-11#orthology", "database": "AGR" }, { "id": "HGNC:29994", "url": "https://alliancegenome.org/gene/HGNC:29994#orthology", "database": "AGR" }, { "id": "HGNC:24465", "url": "https://alliancegenome.org/gene/HGNC:24465#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VA44-1", "protein_name": "CLIP domain-containing serine protease", "gene_name": "c-SP11", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKVIAAVLLCLLIIRTAHGQYVSCRNPNQRTGYCVNIPLCVPLNSVLAKSNPTDSEMRFIRESRCLVSDQSDLPFVCCTPDTDYNTTRARPNDEVIHSTLLPDRSICGGDIAYNQITKGNETVLTEFAWMVLLEYRPHDGQQLRTYCAGSLINNRYVVTAAHCVSAATRARKGDVSFRVSVRLGEHNTSAVVDCLNGRCLPEPVQIAVEEIRIHESFGTRLFWNDIALIRLAREVAYSPSIRPVCLPSTVGLQNWQSGQAFTVAGWGRTLTSESSPVKMKLRVTYVEPGLCRRKYASIVVLGDSHLCAEGRSRGDSCDGDSGGPLMAFHEGVWVLGGIVSFGLNCGSRFWPAVYTNVLSYETWITQNIRP", "length": 370 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-051127-11", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-051127-11#orthology", "database": "AGR" }, { "id": "HGNC:29994", "url": "https://alliancegenome.org/gene/HGNC:29994#orthology", "database": "AGR" }, { "id": "HGNC:24465", "url": "https://alliancegenome.org/gene/HGNC:24465#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VA87-1", "protein_name": "CLIP domain-containing serine protease", "gene_name": "c-SP10", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKVFAAVFLCILIAHEAKAQSDSRCLNPNQTPGLCVLINECQTLYSVLKRATLTDQEKSFIKSSACGRGSNNQPYVCCTQDTGYVRIQRQDRTFPDYGAFGGDWEEERPQSFVFPRQERRPWSFGNQPATSRTPFRKSSTSDGSSLLPQPPSCGGVGIRNRIYDGQDTDVNEFPWMVLLEYRRRSGNGLSTACAGSLINRRYVLTAAHCLTGRIEREVGTLVSVRLGEHDTRTAVDCPPGGGSCSPEVQRLGFEEIRVHERYSEKASNQVHDIGLIRMERNVRYSDNIQPICLPSSVGLESRQSGQQFTVAGWGRTLKMARSAVKQKVTVNYVDPAKCRQRFSQIKVNLEPTQLCAGGQFRKDSCDGDSGGPLMRFRDESWVLEGIVSFGYKCGLKDWPGVYTNVAAYDIWIRQNVRA", "length": 418 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-051127-11", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-051127-11#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VB66-1", "protein_name": "CLIP domain-containing serine protease", "gene_name": "c-SP8", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVSAAIRLGLLLCILPQLVISQSSCVTPAQAAGQCIRYQECPFVQKILGIYGRNIPRKIHNQISEMQCRSTTNTRDFHLCCPNEAPPQSNQESQRKVVRSEGGNLNRYDRQGLQLLNSVTNCGNKGNPKVSGGKTARPGDFPWVALLKYKINDPRPFRCGGSLISERHILTAAHCIIDQPEVIAVRLGEHDLESEEDCHYLGGTNRVCIPPYEEYGIEQIRVHPNYVHGKISHDVAIIKLDRVVKEKSHIKPVCLPIDQKSQELDFDQSFFVAGWGGTEKETVATKLQQALITRKSLNECRQYYNKGEVSDNHICATGTGIKHTCQGDSGGPVFFKHRFKNTYRVVQYGVVSFGGRLCGQNQPGVFASVIDMLPWITQNLQ", "length": 381 }, "evidence": [ { "id": "HGNC:29994", "url": "https://alliancegenome.org/gene/HGNC:29994#orthology", "database": "AGR" }, { "id": "HGNC:24465", "url": "https://alliancegenome.org/gene/HGNC:24465#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VCJ8-1", "protein_name": "Spaetzle-processing enzyme", "gene_name": "SPE", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MASTERNFLLLSLVVSALSGLVHRSDAAEISFGSCTPQQSDERGQCVHITSCPYLANLLMVEPKTPAQRILLSKSQCGLDNRVEGLVNRILVCCPQSMRGNIMDSEPTPSTRDALQQGDVLPGNDVCGFLFADRIFGGTNTTLWEFPWMVLLQYKKLFSETYTFNCGGALLNSRYVLTAGHCLASRELDKSGAVLHSVRLGEWDTRTDPDCTTQMNGQRICAPKHIDIEVEKGIIHEMYAPNSVDQRNDIALVRLKRIVSYTDYVRPICLPTDGLVQNNFVDYGMDVAGWGLTENMQPSAIKLKITVNVWNLTSCQEKYSSFKVKLDDSQMCAGGQLGVDTCGGDSGGPLMVPISTGGRDVFYIAGVTSYGTKPCGLKGWPGVYTRTGAFIDWIKQKLEP", "length": 400 }, "evidence": [ { "id": "HGNC:29994", "url": "https://alliancegenome.org/gene/HGNC:29994#orthology", "database": "AGR" }, { "id": "HGNC:24465", "url": "https://alliancegenome.org/gene/HGNC:24465#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VET2-1", "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "Dmel\\CG14892", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MMKPSQSQLHSQSQTQSRPKSRLQSRPQSRSQSLSQSQCHWQIPATSTATLSWLCLLLLLPSSRQFETDCGCRPARRGPRIIAGAATNEGQFPWQASLELLHPSLGFLGHWCGAVLIHQYWILSAAHCVHNDLFNLPIPPLWTVVLGEHDRDVESGNEQRIPVEKIVMHHRYHNFKHDVVLMKLSKPADLTRASNIRRICLPFLLAESPDQAQSETVSPPSSADEDVLIQQLELEDVPEKIDNFLRSVQSRRRYRNVTAPSMKELMNMKILSRMRQALAQRSPRSHKRSRRRNDKLMKLGPRRDSDDSAEQKHPKVSDEPKEIAFVDCVATGWGKANISGDLSNQLLKTQVPLHQNGRCRDAYGSFVNIHGGHLCAGKLNGEGGTCVGDSGGPLQCRLSRDGPWILVGVTSFGSGCALEGFPDVYTRTSYYMKWIEDTIATH", "length": 442 }, "evidence": [ { "id": "HGNC:29994", "url": "https://alliancegenome.org/gene/HGNC:29994#orthology", "database": "AGR" }, { "id": "HGNC:24465", "url": "https://alliancegenome.org/gene/HGNC:24465#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VJD6-1", "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "Dmel\\CG18563", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGSIVATAAILLFCVLSGEACRYCVPMEKCLILSRKLNSCPFNHVCCDIIIKSPYIPSGPNEESDSESASSSTEEENIPTFIYFPTRPTVSSEPQNNVSTEPDVPITYWPLKGSGAPTNDGAQAEQPKPTERTQPGGRCNTTGLYSWVVALFYEEVYLTGGSLISPKVILTAAHNTMNKMNEDRIVVRAGEFVMNTTNEPIQYEERVVERIVRHEGFIFQSGINNVALIFVKTPFVLNDRIGVLTLPSRQASFEGRRCTVAGWDLVSSHDQSRMRIIKKLELTVLDRTTCVAQFRNTTLGRNFDLHPSLICARSEINRDFCFGGGGYALFCSLGDENPHVFEQAGIVAWGMGCGLDLPGIYTNVAMFRSWIYNRIAYFG", "length": 379 }, "evidence": [ { "id": "HGNC:14118", "url": "https://alliancegenome.org/gene/HGNC:14118#orthology", "database": "AGR" }, { "id": "HGNC:14120", "url": "https://alliancegenome.org/gene/HGNC:14120#orthology", "database": "AGR" }, { "id": "HGNC:12019", "url": "https://alliancegenome.org/gene/HGNC:12019#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VK10-1", "protein_name": "Phenoloxidase-activating factor 2", "gene_name": "l(2)k05911", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFAFLPVLLLCVHLLHFKIISGVDLPSVSGGALAPGPVWPNGEINAAPEAGLFKANATAEKNLGGTVVDLQPNLNRQRRQFFFDPSILLWQGALGASGVSGGWGPGEGSKCLTSRGQPGVCVRIDGCRQYYRLARQISIFTLRQWPQANGLGLNGNMCNFFDMLGRVNNGICCTDIDANSFGVFPLPGTTTTTTTTTEMPSVVADEEDREHVIPEGEVEGVYPPDVPRPEEPIDNANSVEDTPDFQDINTIEGNPPGADKKPEAEPVGEPVEQPISTQPASTIHPYQWPFGSFAGGQWPPALPTHPPTTGGWPPPLPTHPPNHHYPTHPTTGGVPSTKRTTPRPTSPARPTTTRRPTYPSYPSPVTTTTTTRRPVSGTSSEGLPLQCGNKNPVTPDQERIVGGINASPHEFPWIAVLFKSGKQFCGGSLITNSHILTAAHCVARMTSWDVAALTAHLGDYNIGTDFEVQHVSRRIKRLVRHKGFEFSTLHNDVAILTLSEPVPFTREIQPICLPTSPSQQSRSYSGQVATVAGWGSLRENGPQPSILQKVDIPIWTNAECARKYGRAAPGGIIESMICAGQAAKDSCSGDSGGPMVINDGGRYTQVGIVSWGIGCGKGQYPGVYTRVTSLLPWIYKNIK", "length": 639 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-051127-11", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-051127-11#orthology", "database": "AGR" }, { "id": "HGNC:14118", "url": "https://alliancegenome.org/gene/HGNC:14118#orthology", "database": "AGR" }, { "id": "HGNC:14120", "url": "https://alliancegenome.org/gene/HGNC:14120#orthology", "database": "AGR" }, { "id": "HGNC:12019", "url": "https://alliancegenome.org/gene/HGNC:12019#orthology", "database": "AGR" }, { "id": "HGNC:14134", "url": "https://alliancegenome.org/gene/HGNC:14134#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VR15-1", "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "Dmel\\CG3355", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRVYLALPLLLLGIGLSLAQYQYQAPHQTLAQQFADVVDVVDPAEQSIKAVRPPKSRNQCTAKQNCFCGTPNVNRIVGGQQVRSNKYPWTAQLVKGRHYPRLFCGGSLINDRYVLTAAHCVHGNRDQITIRLLQIDRSSRDPGIVRKVVQTTVHPNYDPNRIVNDVALLKLESPVPLTGNMRPVCLPEANHNFDGKTAVVAGWGLIKEGGVTSNYLQEVNVPVITNAQCRQTRYKDKIAEVMLCAGLVQQGGKDACQGDSGGPLIVNEGRYKLAGVVSFGYGCAQKNAPGVYARVSKFLDWIRKNTADGCYCQS", "length": 314 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-051127-11", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-051127-11#orthology", "database": "AGR" }, { "id": "HGNC:14118", "url": "https://alliancegenome.org/gene/HGNC:14118#orthology", "database": "AGR" }, { "id": "HGNC:14120", "url": "https://alliancegenome.org/gene/HGNC:14120#orthology", "database": "AGR" }, { "id": "HGNC:12019", "url": "https://alliancegenome.org/gene/HGNC:12019#orthology", "database": "AGR" }, { "id": "HGNC:14134", "url": "https://alliancegenome.org/gene/HGNC:14134#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141212-262", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141212-262#orthology", "database": "AGR" }, { "id": "RGD:620766", "url": "https://alliancegenome.org/gene/RGD:620766#orthology", "database": "AGR" }, { "id": "RGD:1310135", "url": "https://alliancegenome.org/gene/RGD:1310135#orthology", "database": "AGR" }, { "id": "RGD:628625", "url": "https://alliancegenome.org/gene/RGD:628625#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VUF0-1", "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "SP40", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKLNPPAFLLLLALISICDRSWAVYNYKPPSRGYFYPKPERLPPLPVNGSTTSSTGPPPGVQSDFIDDLIEGHKQQILSNVLGVASETPSDTASSLGSTSLSSSASPVFPLEGGGAKAFRVNRCASCTCGVPNVNRIVGGTQVRTNKYPWIAQIIRGTFLFCGGTLINDRYVLTAAHCVHGMDMRGVSVRLLQLDRSSTHLGVTRSVAFAHAHVGYDPVSLVHDIALLRLDQPIPLVDTMRPACLPSNWLQNFDFQKAIVAGWGLSQEGGSTSSVLQEVVVPIITNAQCRATSYRSMIVDTMMCAGYVKTGGRDACQGDSGGPLIVRDRIFRLAGVVSFGYGCAKPDAPGVYTRVSRYLEWIAVNTRDSCYCIN", "length": 374 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-051127-11", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-051127-11#orthology", "database": "AGR" }, { "id": "HGNC:14118", "url": "https://alliancegenome.org/gene/HGNC:14118#orthology", "database": "AGR" }, { "id": "HGNC:14120", "url": "https://alliancegenome.org/gene/HGNC:14120#orthology", "database": "AGR" }, { "id": "HGNC:12019", "url": "https://alliancegenome.org/gene/HGNC:12019#orthology", "database": "AGR" }, { "id": "HGNC:14134", "url": "https://alliancegenome.org/gene/HGNC:14134#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141212-262", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141212-262#orthology", "database": "AGR" }, { "id": "RGD:620766", "url": "https://alliancegenome.org/gene/RGD:620766#orthology", "database": "AGR" }, { "id": "RGD:1310135", "url": "https://alliancegenome.org/gene/RGD:1310135#orthology", "database": "AGR" }, { "id": "RGD:628625", "url": "https://alliancegenome.org/gene/RGD:628625#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VW19-1", "protein_name": "Phenoloxidase-activating factor 2", "gene_name": "Dmel\\CG9372", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKAFLWALVILLGYIPQSTIAKTVSTDFLDLLDFSDNDEFQWGESENQVYENRTGENRVVSFLSQHRLNKRQAPTSQLLENKDYGACSTPLGESGRCRHIIYCRMPELKNDVWRLVSQLCIIEKSSIGICCTDQSTSNRFSPQVVTSADGDEPRIVNKPEQRGCGITSRQFPRLTGGRPAEPDEWPWMAALLQEGLPFVWCGGVLITDRHVLTAAHCIYKKNKEDIFVRLGEYNTHMLNETRARDFRIANMVLHIDYNPQNYDNDIAIVRIDRATIFNTYIWPVCMPPVNEDWSDRNAIVTGWGTQKFGGPHSNILMEVNLPVWKQSDCRSSFVQHVPDTAMCAGFPEGGQDSCQGDSGGPLLVQLPNQRWVTIGIVSWGVGCGQRGRPGIYTRVDRYLDWILANADV", "length": 408 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-051127-11", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-051127-11#orthology", "database": "AGR" }, { "id": "HGNC:14118", "url": "https://alliancegenome.org/gene/HGNC:14118#orthology", "database": "AGR" }, { "id": "HGNC:14120", "url": "https://alliancegenome.org/gene/HGNC:14120#orthology", "database": "AGR" }, { "id": "HGNC:12019", "url": "https://alliancegenome.org/gene/HGNC:12019#orthology", "database": "AGR" }, { "id": "HGNC:14134", "url": "https://alliancegenome.org/gene/HGNC:14134#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VZH5-1", "protein_name": "CLIP domain-containing serine protease", "gene_name": "SP18", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKSMCCVSAVITLLPLVLLPPPTVAQFNQRRQVRQNCITPENYYGSCVALTYCPQVVNIFQTTSRDRAQRYVIALQRSCGTRSINGDPVICCTEPRYNPVTERPRNPFFPSESTFIGPQPPPEVPDNPFLIPTPRTTTTTTTTTPAPIPDTSAAPLIEPRGTVCRGPDTKPGNCVEIKECASLLNELRSRSQDATFANFLRASNAVCQNKGTQVCCPTGQGITNTTPAPSQIVPKNTDEIPRRLLNVEEGCGSTVGYFKKIVGGEVSRKGAWPWIALLGYDDPSGSPFKCGGTLITARHVLTAAHCIRQDLQFVRLGEHDLSTDTETGHVDINIARYVSHPDYNRRNGRSDMAILYLERNVEFTSKIAPICLPHTANLRQKSYVGYMPFVAGWGKTMEGGESAQVLNELQIPIYDNKVCVQSYAKEKRYFSADQFDKAVLCAGVLSGGKDTCQGDSGGPLMLPEPYQGQLRFYLIGVVSYGIGCARPNVPGVYSSTQYFMDWIIQQVQDTP", "length": 511 }, "evidence": [ { "id": "HGNC:14118", "url": "https://alliancegenome.org/gene/HGNC:14118#orthology", "database": "AGR" }, { "id": "HGNC:14120", "url": "https://alliancegenome.org/gene/HGNC:14120#orthology", "database": "AGR" }, { "id": "HGNC:12019", "url": "https://alliancegenome.org/gene/HGNC:12019#orthology", "database": "AGR" }, { "id": "HGNC:14134", "url": "https://alliancegenome.org/gene/HGNC:14134#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W2C8-1", "protein_name": "3.4.21.-", "gene_name": "tpr", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNRAWLCLLICLALSCGPSQSASQDRATNQTAASPLLKQSQNTFIQWVLSLLPQRPGSSDSENATLATLSSSSMMPDAASTTSTTTPAPSSSTTTTRRATTPAPPTLNPPRNCSDCVCGIANIQKRIVGGQETEVHQYPWVAMLLYGGRFYCAASLLNDQFLLTASHCVYGFRKERISVRLLEHDRKMSHMQKIDRKVAEVITHPKYNARNYDNDIAIIKLDEPVEFNEVLHPVCMPTPGRSFKGENGIVTGWGALKVGGPTSDTLQEVQVPILSQDECRKSRYGNKITDNMLCGGYDEGGKDSCQGDSGGPLHIVASGTREHQIAGVVSWGEGCAKAGYPGVYARVNRYGTWIKNLTKQACLCQQETKKIK", "length": 372 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-051127-11", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-051127-11#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141212-262", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141212-262#orthology", "database": "AGR" }, { "id": "RGD:620766", "url": "https://alliancegenome.org/gene/RGD:620766#orthology", "database": "AGR" }, { "id": "RGD:1310135", "url": "https://alliancegenome.org/gene/RGD:1310135#orthology", "database": "AGR" }, { "id": "RGD:628625", "url": "https://alliancegenome.org/gene/RGD:628625#orthology", "database": "AGR" }, { "id": "MGI:3521861", "url": "https://alliancegenome.org/gene/MGI:3521861#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "Q9VUG2", "url": "https://www.uniprot.org/uniprotkb/Q9VUG2" } ], "pmid": "" }, { "name": "serine hydrolase activity", "id": "GO:0017171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017171", "evidence": [ { "database": "UniProtKB", "id": "Q9VUG2", "url": "https://www.uniprot.org/uniprotkb/Q9VUG2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VUG2", "url": "https://www.uniprot.org/uniprotkb/Q9VUG2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VUG2", "url": "https://www.uniprot.org/uniprotkb/Q9VUG2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9VUG2", "url": "https://www.uniprot.org/uniprotkb/Q9VUG2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 102, "end_pos": 104, "annotation": "n_glycosylation_sequon" }, { "start_pos": 109, "end_pos": 111, "annotation": "n_glycosylation_sequon" }, { "start_pos": 287, "end_pos": 289, "annotation": "n_glycosylation_sequon" }, { "start_pos": 76, "end_pos": 78, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VUG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUG2" }, { "id": "PS50240", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50240" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase S1", "eco_id": "ECO_0000259", "start_pos": 128, "end_pos": 365, "start_aa": "Ile", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 28, 31, 34 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 102, "end_pos": 104 }, { "start_pos": 109, "end_pos": 111 }, { "start_pos": 287, "end_pos": 289 }, { "start_pos": 76, "end_pos": 78 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": 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"table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VUJ8-1", "uniprot_ac": "Q9VUJ8", "uniprot_id": "Q9VUJ8_DROME", "mass": { "chemical_mass": 12113.0, "monoisotopic_mass": 12113.0 }, "refseq": { "ac": "NP_648737", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648737" }, "gene_names": [ { "name": "BcDNA:RE02926", "type": "recommended", "evidence": [ { "id": "Q9VUJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUJ8" } ] }, { "name": "BcDNA:RE02926", "type": "synonym", "evidence": [ { "id": "NP_648737", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648737" } ] }, { "name": "CG12310", "type": "synonym", "evidence": [ { "id": "NP_648737", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648737" }, { "id": "Q9VUJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUJ8" } ] }, { "name": "Dmel\\CG12310", "type": "synonym", "evidence": [ { "id": "NP_648737", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648737" }, { "id": "Q9VUJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUJ8" } ] }, { "name": "Dmel_CG12310", "type": "synonym", "evidence": [ { "id": "Q9VUJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUJ8" } ] }, { "name": "chr3L:15015907..15016009", "type": "synonym", "evidence": [ { "id": "NP_648737", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648737" }, { "id": "Q9VUJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUJ8" } ] } ], "protein_names": [ { "name": "CG12310-PA", "type": "synonym", "evidence": [ { "id": "NP_648737", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648737" } ] }, { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "Q9VUJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUJ8/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_648737", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648737" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VUJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VUJ8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "BcDNA:RE02926", "url": "https://www.uniprot.org/uniprotkb/Q9VUJ8", "locus": { "chromosome": "3L", "start_pos": 15050263, "end_pos": 15050806, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0036467", "url": "https://www.ensemblgenomes.org/id/FBgn0036467" } ] } } ], "crossref": [ { "id": "FB:FBgn0036467", "url": "https://alliancegenome.org/gene/FB:FBgn0036467", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0036467", "url": "https://bgee.org/?page=gene&gene_id=FBgn0036467", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0036467", "url": "https://flybase.org/reports/FBgn0036467", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "39634", "url": "https://www.ncbi.nlm.nih.gov/gene/39634", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VUJ8", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VUJ8*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "dme:Dmel_CG12310", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG12310", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "STPFWPR", "url": "https://omabrowser.org/oma/group/STPFWPR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "NP_648737", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648737", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VUJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VUJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VUJ8-1", "url": "https://www.uniprot.org/uniprotkb/Q9VUJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRSLILVALLAFLAVGFVAARPAEDEESSAAVVENADEDSTSNDAESTEATDAEESSDDEETTEESGDAADESSDDADEDETTTAASAKKQIRPFWPRFGGHGPVVIRRHPSLV", "length": 114, "header": "tr|Q9VUJ8-1|Q9VUJ8_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=BcDNA:RE02926 PE=4 SV=1 CANONICAL=Q9VUJ8-1" }, "isoforms": [ { "isoform_ac": "Q9VUJ8-1", "url": "https://www.uniprot.org/uniprotkb/Q9VUJ8/entry#Q9VUJ8-1", "sequence": { "sequence": "MRSLILVALLAFLAVGFVAARPAEDEESSAAVVENADEDSTSNDAESTEATDAEESSDDEETTEESGDAADESSDDADEDETTTAASAKKQIRPFWPRFGGHGPVVIRRHPSLV", "length": 114, "header": "tr|Q9VUJ8-1|Q9VUJ8_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=BcDNA:RE02926 PE=4 SV=1 CANONICAL=Q9VUJ8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VUJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VUJ8" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VUJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VUJ8" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VUJ8" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VUJ8" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VUJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VUJ8" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VUJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VUJ8" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VUJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VUJ8" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VUJ8" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VUJ8" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VUJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VUJ8" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VUJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VUJ8" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG12310", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG12310", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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[ { "id": "NP_648752", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648752" } ] }, { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "Q9VUL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUL6/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein, isoform A", "type": "synonym", "evidence": [ { "id": "NP_648752", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648752" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VUL6", "url": "https://www.uniprot.org/uniprotkb/Q9VUL6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG12316", "url": "https://www.uniprot.org/uniprotkb/Q9VUL6", "locus": { 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"length": 1188, "header": "tr|Q9VUL6-1|Q9VUL6_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG12316 PE=4 SV=1 CANONICAL=Q9VUL6-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 658, "start_aa": "Thr", "end_pos": 658, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr658", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VUL6", "url": "https://www.uniprot.org/uniprotkb/Q9VUL6" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VUL6", "url": "https://www.uniprot.org/uniprotkb/Q9VUL6" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUL6", "url": "https://www.uniprot.org/uniprotkb/Q9VUL6" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUL6", "url": "https://www.uniprot.org/uniprotkb/Q9VUL6" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VUL6", "url": "https://www.uniprot.org/uniprotkb/Q9VUL6" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VUL6", "url": "https://www.uniprot.org/uniprotkb/Q9VUL6" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VUL6", "url": "https://www.uniprot.org/uniprotkb/Q9VUL6" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUL6", "url": "https://www.uniprot.org/uniprotkb/Q9VUL6" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUL6", "url": "https://www.uniprot.org/uniprotkb/Q9VUL6" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUM1" } ] }, { "name": "FBgn0036487", "type": "synonym", "evidence": [ { "id": "NP_648756", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648756" }, { "id": "Q9VUM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUM1" } ] }, { "name": "Prp31", "type": "synonym", "evidence": [ { "id": "NP_648756", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648756" } ] }, { "name": "anon-EST:Liang-2.38", "type": "synonym", "evidence": [ { "id": "NP_648756", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648756" }, { "id": "Q9VUM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUM1" } ] }, { "name": "clone 2.38", "type": "synonym", "evidence": [ { "id": "NP_648756", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648756" }, { "id": "Q9VUM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUM1" } ] }, { "name": "prp31", "type": "synonym", "evidence": [ { "id": "NP_648756", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648756" }, { "id": "Q9VUM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUM1" } ] } ], "protein_names": [ { "name": "U4/U6 small nuclear ribonucleoprotein Prp31", "type": "recommended", "evidence": [ { "id": "Q9VUM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUM1/entry#names_and_taxonomy" } ] }, { "name": "CG6876-PA", "type": "synonym", "evidence": [ { "id": "NP_648756", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648756" } ] }, { "name": "Pre-mRNA processing factor 31", "type": "synonym", "evidence": [ { "id": "NP_648756", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648756" } ] }, { "name": "Pre-mRNA-processing factor 31", "type": "synonym", "evidence": [ { "id": "Q9VUM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUM1/entry#names_and_taxonomy" } ] }, { "name": "Prp31-PA", "type": "synonym", "evidence": [ { "id": "NP_648756", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648756" } ] } ], "function": [ { "annotation": "Involved in pre-mRNA splicing as component of the spliceosome. Required for the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome.", "evidence": [ { "database": "UniProtKB", "id": "Q9VUM1", "url": "https://www.uniprot.org/uniprotkb/Q9VUM1#function" }, { "database": "UniProtKB", "id": "ARBA00045397", "url": "https://www.uniprot.org/uniprotkb/ARBA00045397#function" } ] } ], "disease": [ { "disease_id": "DOID:0110408", "recommended_name": { "id": "DOID:0110408", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110408", "name": "retinitis pigmentosa 11", "description": "A retinitis pigmentosa that has_material_basis_in mutation in the PRPF31 gene on chromosome 19q13." }, "synonyms": [ { "id": "DOID:0110408", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110408", "name": "RP11", "description": "" }, { "id": "MONDO:0010828", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010828", "name": "retinitis pigmentosa 11", "description": "Any retinitis pigmentosa in which the cause of the disease is a mutation in the PRPF31 gene." }, { "id": "MONDO:0010828", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010828", "name": "PRPF31 retinitis pigmentosa", "description": "" }, { "id": "MONDO:0010828", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010828", "name": "RP11", "description": "" }, { "id": "MONDO:0010828", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010828", "name": "retinitis pigmentosa 11", "description": "" }, { "id": "MONDO:0010828", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010828", "name": "retinitis pigmentosa caused by mutation in PRPF31", "description": "" }, { "id": "MONDO:0010828", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010828", "name": "retinitis pigmentosa type 11", "description": "" }, { "id": "MONDO:0010828", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010828", "name": "RP 11", "description": "" }, { "id": "MIM:600138", "resource": "MIM", "url": "https://www.omim.org/entry/600138", "name": "Retinitis pigmentosa 11", "description": "Retinitis pigmentosa 11" } ], "unlinked_id_list": [], "evidence": [ { "id": "0110408", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110408" } ] }, { "disease_id": "DOID:10584", "recommended_name": { "id": "DOID:10584", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10584", "name": "retinitis pigmentosa", "description": "A retinal degeneration characterized by the gradual deterioration of the photoreceptors or the retinal pigment epithelium of the retina leading to progressive sight loss." }, "synonyms": [ { "id": "DOID:10584", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10584", "name": "pericentral pigmentary retinopathy", "description": "" }, { "id": "MONDO:0019200", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019200", "name": "retinitis pigmentosa", "description": "Retinitis pigmentosa (RP) is an inherited retinal dystrophy leading to progressive loss of the photoreceptors and retinal pigment epithelium and resulting in blindness usually after several decades." }, { "id": "MONDO:0019200", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019200", "name": "retinitis pigmentosa", "description": "" }, { "id": "MONDO:0019200", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019200", "name": "pericentral pigmentary retinopathy", "description": "" }, { "id": "MONDO:0019200", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019200", "name": "Rod-cone dystrophy", "description": "" }, { "id": "MIM:268000", "resource": "MIM", "url": "https://www.omim.org/entry/268000", "name": "Retinitis pigmentosa", "description": "Retinitis pigmentosa" } ], "unlinked_id_list": [], "evidence": [ { "id": "10584", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10584" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VUM1", "url": "https://www.uniprot.org/uniprotkb/Q9VUM1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Prp31", "url": "https://www.uniprot.org/uniprotkb/Q9VUM1", "locus": { "chromosome": "3L", "start_pos": 15161138, "end_pos": 15159100, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0036487", "url": "https://www.ensemblgenomes.org/id/FBgn0036487" } ] } } ], "crossref": [ { "id": "FB:FBgn0036487", "url": "https://alliancegenome.org/gene/FB:FBgn0036487", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0036487", "url": "https://bgee.org/?page=gene&gene_id=FBgn0036487", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0036487", "url": "https://flybase.org/reports/FBgn0036487", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "39655", "url": "https://www.ncbi.nlm.nih.gov/gene/39655", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VUM1", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VUM1*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR002687", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002687", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012976", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012976", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019175", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019175", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027105", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027105", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036070", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036070", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042239", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042239", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG6876", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG6876", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IGNGPMD", "url": "https://omabrowser.org/oma/group/IGNGPMD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VUM1", "url": "https://www.orthodb.org/?gene=Q9VUM1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13904", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13904", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13904:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13904:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01798", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01798", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09785", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09785", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_648756", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648756", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VUM1", "url": "https://www.uniprot.org/uniprotkb/Q9VUM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VUM1-1", "url": "https://www.uniprot.org/uniprotkb/Q9VUM1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLADELLADLEEDNDNELEEEDSEMASAEDESLLAEKLAKPAPNLMDVDVTVQSVRELCKLRDSERLKNTLQQIEHYASRQRTAAEMLGSVESDPEYCLIVDANAIAVDIDNEISIVHKFTKEKYQKRFPELDSLIVGEIEYLLAVKELGNDLDQVKNNEKLQAILTQATIMIVSVTASTTQGTMLTPAEKAKIDEACEMAIELNNFKSKIYEYVESRMTFIAPNLSMIVGASTAAKLLGIAGGLSKLSKMPACNVQVLGAQKKTLSGFSQTQMLPHTGYVYYSQIVQDTAPDLRRKAARLVAAKSVLAARVDACHESVHGEIGLRFKEDVEKKLDKLQEPPPVKFIKPLPKPIEGSKKKRGGKRVRKMKERYALTEFRKQANRMNFGDIEEDAYQGDLGYSRGTIGKTGTGRIRLPQVDEKTKVRISKTLHKNLQKQQVYGGNTTVKRQISGTASSVAFTPLQGLEIVNPQAAERSQTEANAKYFSNTSGFMSVGQRTT", "length": 501, "header": "tr|Q9VUM1-1|Q9VUM1_DROME Isoform 1 of U4/U6 small nuclear ribonucleoprotein Prp31 OS=Drosophila melanogaster OX=7227 GN=Prp31 PE=1 SV=1 CANONICAL=Q9VUM1-1" }, "isoforms": [ { "isoform_ac": "Q9VUM1-1", "url": "https://www.uniprot.org/uniprotkb/Q9VUM1/entry#Q9VUM1-1", "sequence": { "sequence": "MSLADELLADLEEDNDNELEEEDSEMASAEDESLLAEKLAKPAPNLMDVDVTVQSVRELCKLRDSERLKNTLQQIEHYASRQRTAAEMLGSVESDPEYCLIVDANAIAVDIDNEISIVHKFTKEKYQKRFPELDSLIVGEIEYLLAVKELGNDLDQVKNNEKLQAILTQATIMIVSVTASTTQGTMLTPAEKAKIDEACEMAIELNNFKSKIYEYVESRMTFIAPNLSMIVGASTAAKLLGIAGGLSKLSKMPACNVQVLGAQKKTLSGFSQTQMLPHTGYVYYSQIVQDTAPDLRRKAARLVAAKSVLAARVDACHESVHGEIGLRFKEDVEKKLDKLQEPPPVKFIKPLPKPIEGSKKKRGGKRVRKMKERYALTEFRKQANRMNFGDIEEDAYQGDLGYSRGTIGKTGTGRIRLPQVDEKTKVRISKTLHKNLQKQQVYGGNTTVKRQISGTASSVAFTPLQGLEIVNPQAAERSQTEANAKYFSNTSGFMSVGQRTT", "length": 501, "header": "tr|Q9VUM1-1|Q9VUM1_DROME Isoform 1 of U4/U6 small nuclear ribonucleoprotein Prp31 OS=Drosophila melanogaster OX=7227 GN=Prp31 PE=1 SV=1 CANONICAL=Q9VUM1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VUM1", "url": "https://www.uniprot.org/uniprotkb/Q9VUM1" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VUM1", "url": "https://www.uniprot.org/uniprotkb/Q9VUM1" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUM1", "url": "https://www.uniprot.org/uniprotkb/Q9VUM1" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUM1", "url": "https://www.uniprot.org/uniprotkb/Q9VUM1" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VUM1", "url": "https://www.uniprot.org/uniprotkb/Q9VUM1" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VUM1", "url": "https://www.uniprot.org/uniprotkb/Q9VUM1" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VUM1", "url": "https://www.uniprot.org/uniprotkb/Q9VUM1" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUM1", "url": "https://www.uniprot.org/uniprotkb/Q9VUM1" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUM1", "url": "https://www.uniprot.org/uniprotkb/Q9VUM1" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VUM1", "url": "https://www.uniprot.org/uniprotkb/Q9VUM1" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VUM1", "url": "https://www.uniprot.org/uniprotkb/Q9VUM1" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG6876", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG6876", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZI68-1", "protein_name": "U4/U6 small nuclear ribonucleoprotein Prp31", "gene_name": "Prpf31", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLADELLADLEEAAEEEEGGSYGEEEEEPAIEDVQEETQLDLSGDSVKSIAKLWDSKMFAEIMMKIEEYISKQAKASEVMGPVEAAPEYRVIVDANNLTVEIENELNIIHKFIRDKYSKRFPELESLVPNALDYIRTVKELGNSLDKCKNNENLQQILTNATIMVVSVTASTTQGQQLSDEELERLEEACDMALELNASKHRIYEYVESRMSFIAPNLSIIIGASTAAKIMGVAGGLTNLSKMPACNIMLLGAQRKTLSGFSSTSVLPHTGYIYHSDIVQSLPPDLRRKAARLVAAKCTLAARVDSFHESTEGKVGYELKDEIERKFDKWQEPPPVKQVKPLPAPLDGQRKKRGGRRYRKMKERLGLTEIRKQANRMSFGEIEEDAYQEDLGFSLGHLGKSGSGRVRQTQVNEATKARISKTLQRTLQKQSVVYGGKSTIRDRSSGTASSVAFTPLQGLEIVNPQAAEKKVAEANQKYFSSMAEFLKVKGEKSGTMST", "length": 499 }, "evidence": [ { "id": "RGD:1305832", "url": "https://alliancegenome.org/gene/RGD:1305832#orthology", "database": "AGR" }, { "id": "MGI:1916238", "url": "https://alliancegenome.org/gene/MGI:1916238#orthology", "database": "AGR" }, { "id": "HGNC:15446", "url": "https://alliancegenome.org/gene/HGNC:15446#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1561", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1561#orthology", "database": "AGR" }, { "id": "FB:FBgn0036487", "url": "https://alliancegenome.org/gene/FB:FBgn0036487#orthology", "database": "AGR" }, { "id": "SGD:S000003323", "url": "https://alliancegenome.org/gene/SGD:S000003323#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P49704-1", "protein_name": "Pre-mRNA-processing factor 31", "gene_name": "PRP31", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSSEEDYFDELEYDLADEVNEEKEDIQTKKLTTVNCQTEKFNPFEILPESIELFRTLALISPDRLSLSETAQILPKIVDLKRILQQQEIDFIKLLPFFNEIIPLIKSNIKLMHNFLISLYSRRFPELSSLIPSPLQYSKVISILENENYSKNESDELFFHLENKAKLTREQILVLTMSMKTSFKNKEPLDIKTRTQILEANSILENLWKLQEDIGQYIASKISIIAPNVCFLVGPEIAAQLIAHAGGVLEFSRIPSCNIASIGKNKHLSHELHTLESGVRQEGYLFASDMIQKFPVSVHKQMLRMLCAKVSLAARVDAGQKNGDRNTVLAHKWKAELSKKARKLSEAPSISETKALPIPEDQPKKKRAGRKFRKYKEKFRLSHVRQLQNRMEFGKQEQTVLDSYGEEVGLGMSNTSLQQAVGATSGSRRSAGNQAKLTKVMKHRISEANQQADEFLISLGHNTEQPNLSPEMVQMHKKQHTNPEEETNWFSGHG", "length": 494 }, "evidence": [ { "id": "RGD:1305832", "url": "https://alliancegenome.org/gene/RGD:1305832#orthology", "database": "AGR" }, { "id": "MGI:1916238", "url": "https://alliancegenome.org/gene/MGI:1916238#orthology", "database": "AGR" }, { "id": "HGNC:15446", "url": "https://alliancegenome.org/gene/HGNC:15446#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1561", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1561#orthology", "database": "AGR" }, { "id": "FB:FBgn0036487", "url": "https://alliancegenome.org/gene/FB:FBgn0036487#orthology", "database": "AGR" }, { "id": "SGD:S000003323", "url": "https://alliancegenome.org/gene/SGD:S000003323#orthology", "database": "AGR" }, { "id": "Q9VUM1", "url": "https://omabrowser.org/oma/group/Q9VUM1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q7SXM7-1", "protein_name": "U4/U6 small nuclear ribonucleoprotein Prp31", "gene_name": "prpf31", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSLADELLADLEEAGEEDGLYPGGEEGESDGEPGERQVDGGLEDIPEEMEVDYSSTESVTSIAKLRHSKPFAEIMDKISHYVGNQRKNSEVSGPVEADPEYRLIVAANNLTVEIDNELNIIHKFVRDKYSKRFPELESLVPNALDYIRTVKELGNNLEKCKNNETLQQILTNATIMVVSVTASTTQGTMLGDDELQRLEEACDMALELNQSKHRIYEYVESRMSFIAPNLSIIVGASTAAKIMGVAGGLTNLSKMPACNLMLLGAQRRTLSGFSSTSLLPHTGYIYHCDVVQTLPPDLRRKAARLVSAKCTLASRVDSFHESADGKVGYDLKEEIERKFDKWQEPPPVKQVKPLPAPLDGQRKKRGGRRYRKMKERLGLTEIRKHANRMTFAEIEDDAYQEDLGFSLGQLGKSGSGRVRQAQVNDSTKARISKSLQRTLQKQSMTYGGKSTVRDRSSGTSSSVAFTPLQGLEIVNPQAAEKKVAEANQKYFSNMAEFLKVKREKEDKV", "length": 508 }, "evidence": [ { "id": "RGD:1305832", "url": "https://alliancegenome.org/gene/RGD:1305832#orthology", "database": "AGR" }, { "id": "MGI:1916238", "url": "https://alliancegenome.org/gene/MGI:1916238#orthology", "database": "AGR" }, { "id": "HGNC:15446", "url": "https://alliancegenome.org/gene/HGNC:15446#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1561", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1561#orthology", "database": "AGR" }, { "id": "FB:FBgn0036487", "url": "https://alliancegenome.org/gene/FB:FBgn0036487#orthology", "database": "AGR" }, { "id": "SGD:S000003323", "url": "https://alliancegenome.org/gene/SGD:S000003323#orthology", "database": "AGR" }, { "id": "Q9VUM1", "url": "https://omabrowser.org/oma/group/Q9VUM1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8CCF0-1", "protein_name": "U4/U6 small nuclear ribonucleoprotein Prp31", "gene_name": "Prpf31", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSLADELLADLEEAAEEEEGGSYGEEEEEPAIEDVQEETQLDLSGDSVKSIAKLWDSKMFAEIMMKIEEYISKQANVSEVMGPVEAAPEYRVIVDANNLTVEIENELNIIHKFIRDKYSKRFPELESLVPNALDYIRTVKELGNSLDKCKNNENLQQILTNATIMVVSVTASTTQGQQLSDEELERLEEACDMALELNASKHRIYEYVESRMSFIAPNLSIIIGASTAAKIMGVAGGLTNLSKMPACNIMLLGAQRKTLSGFSSTSVLPHTGYIYHSDIVQSLPPDLRRKAARLVAAKCTLAARVDSFHESTEGKVGYELKDEIERKFDKWQEPPPVKQVKPLPAPLDGQRKKRGGRRYRKMKERLGLTEIRKQANRMSFGEIEEDAYQEDLGFSLGHLGKSGSGRVRQTQVNEATKARISKTLQRTLQKQSVVYGGKSTIRDRSSGTASSVAFTPLQGLEIVNPQAAEKKVAEANQKYFSSMAEFLKVKGEKSGTMST", "length": 499 }, "evidence": [ { "id": "RGD:1305832", "url": "https://alliancegenome.org/gene/RGD:1305832#orthology", "database": "AGR" }, { "id": "MGI:1916238", "url": "https://alliancegenome.org/gene/MGI:1916238#orthology", "database": "AGR" }, { "id": "HGNC:15446", "url": "https://alliancegenome.org/gene/HGNC:15446#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1561", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1561#orthology", "database": "AGR" }, { "id": "FB:FBgn0036487", "url": "https://alliancegenome.org/gene/FB:FBgn0036487#orthology", "database": "AGR" }, { "id": "SGD:S000003323", "url": "https://alliancegenome.org/gene/SGD:S000003323#orthology", "database": "AGR" }, { "id": "Q9VUM1", "url": "https://omabrowser.org/oma/group/Q9VUM1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8RXN6-1", "protein_name": "U4/U6 small nuclear ribonucleoprotein Prp31 homolog", "gene_name": "PRP31", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATLEDSFLADLDELSDNEAELDENDGDVGKEEEDVDMDMADLETLNYDDLDNVSKLQKSQRYADIMHKVEEALGKDSDGAEKGTVLEDDPEYKLIVDCNQLSVDIENEIVIVHNFIKDKYKLKFQELESLVHHPIDYACVVKKIGNETDLALVDLADLLPSAIIMVVSVTALTTKGSALPEDVLQKVLEACDRALDLDSARKKVLEFVESKMGSIAPNLSAIVGSAVAAKLMGTAGGLSALAKMPACNVQVLGHKRKNLAGFSSATSQSRVGYLEQTEIYQSTPPGLQARAGRLVAAKSTLAARVDATRGDPLGISGKAFREEIRKKIEKWQEPPPARQPKPLPVPDSEPKKRRGGRRLRKMKERYQVTDMRKLANRMAFGTPEESSLGDGLGEGYGMLGQAGSNRLRVSSVPSKLKINAKVAKKLKERQYAGGATTSGLTSSLAFTPVQGIELCNPQQALGLGSGTQSTYFSESGTFSKLKKI", "length": 485 }, "evidence": [ { "id": "Q9VUM1", "url": "https://omabrowser.org/oma/group/Q9VUM1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q8WWY3-1", "protein_name": "U4/U6 small nuclear ribonucleoprotein Prp31", "gene_name": "PRPF31", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLADELLADLEEAAEEEEGGSYGEEEEEPAIEDVQEETQLDLSGDSVKTIAKLWDSKMFAEIMMKIEEYISKQAKASEVMGPVEAAPEYRVIVDANNLTVEIENELNIIHKFIRDKYSKRFPELESLVPNALDYIRTVKELGNSLDKCKNNENLQQILTNATIMVVSVTASTTQGQQLSEEELERLEEACDMALELNASKHRIYEYVESRMSFIAPNLSIIIGASTAAKIMGVAGGLTNLSKMPACNIMLLGAQRKTLSGFSSTSVLPHTGYIYHSDIVQSLPPDLRRKAARLVAAKCTLAARVDSFHESTEGKVGYELKDEIERKFDKWQEPPPVKQVKPLPAPLDGQRKKRGGRRYRKMKERLGLTEIRKQANRMSFGEIEEDAYQEDLGFSLGHLGKSGSGRVRQTQVNEATKARISKTLQRTLQKQSVVYGGKSTIRDRSSGTASSVAFTPLQGLEIVNPQAAEKKVAEANQKYFSSMAEFLKVKGEKSGLMST", "length": 499 }, "evidence": [ { "id": "RGD:1305832", "url": "https://alliancegenome.org/gene/RGD:1305832#orthology", "database": "AGR" }, { "id": "MGI:1916238", "url": "https://alliancegenome.org/gene/MGI:1916238#orthology", "database": "AGR" }, { "id": "HGNC:15446", "url": "https://alliancegenome.org/gene/HGNC:15446#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1561", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1561#orthology", "database": "AGR" }, { "id": "FB:FBgn0036487", "url": "https://alliancegenome.org/gene/FB:FBgn0036487#orthology", "database": "AGR" }, { "id": "SGD:S000003323", "url": "https://alliancegenome.org/gene/SGD:S000003323#orthology", "database": "AGR" }, { "id": "Q9VUM1", "url": "https://omabrowser.org/oma/group/Q9VUM1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q9VUM1", "url": "https://www.uniprot.org/uniprotkb/Q9VUM1" } ], "pmid": "" }, { "name": "ribonucleoprotein complex binding", "id": "GO:0043021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043021", "evidence": [ { "database": "UniProtKB", "id": "Q9VUM1", "url": "https://www.uniprot.org/uniprotkb/Q9VUM1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "spliceosomal tri-snRNP complex assembly", "id": "GO:0000244", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000244", "evidence": [ { "database": "UniProtKB", "id": "Q9VUM1", "url": "https://www.uniprot.org/uniprotkb/Q9VUM1" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "Q9VUM1", "url": "https://www.uniprot.org/uniprotkb/Q9VUM1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "Q9VUM1", "url": "https://www.uniprot.org/uniprotkb/Q9VUM1" } ], "pmid": "" }, { "name": "precatalytic spliceosome", "id": "GO:0071011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071011", "evidence": [ { "database": "UniProtKB", "id": "Q9VUM1", "url": "https://www.uniprot.org/uniprotkb/Q9VUM1" } ], "pmid": "" }, { "name": "U4 snRNP", "id": "GO:0005687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005687", "evidence": [ { "database": "UniProtKB", "id": "Q9VUM1", "url": "https://www.uniprot.org/uniprotkb/Q9VUM1" } ], "pmid": "" }, { "name": "U4/U6 x U5 tri-snRNP complex", "id": "GO:0046540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046540", "evidence": [ { "database": "UniProtKB", "id": "Q9VUM1", "url": "https://www.uniprot.org/uniprotkb/Q9VUM1" } ], "pmid": "" }, { "name": "spliceosomal tri-snRNP complex", "id": "GO:0097526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097526", "evidence": [ { "database": "UniProtKB", "id": "Q9VUM1", "url": "https://www.uniprot.org/uniprotkb/Q9VUM1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 226, "end_pos": 228, "annotation": "n_glycosylation_sequon" }, { "start_pos": 445, "end_pos": 447, "annotation": "n_glycosylation_sequon" }, { "start_pos": 489, "end_pos": 491, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VUM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUM1" }, { "id": "PS51358", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51358" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nop", "eco_id": "ECO_0000259", "start_pos": 223, "end_pos": 341, "start_aa": "Ile", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 226, "end_pos": 228 }, { "start_pos": 445, "end_pos": 447 }, { "start_pos": 489, "end_pos": 491 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VUM2-1", "uniprot_ac": "Q9VUM2", "uniprot_id": "Q9VUM2_DROME", "mass": { "chemical_mass": 8237.0, "monoisotopic_mass": 8237.0 }, "refseq": { "ac": "NP_648757", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648757" }, "gene_names": [ { "name": "Dmel\\CG6878", "type": "recommended", "evidence": [ { "id": "Q9VUM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUM2" } ] }, { "name": "CG6878", "type": "synonym", "evidence": [ { "id": "NP_648757", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648757" }, { "id": "Q9VUM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUM2" } ] }, { "name": "Dmel\\CG6878", "type": "synonym", "evidence": [ { "id": "NP_648757", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648757" } ] }, { "name": "Dmel_CG6878", "type": "synonym", "evidence": [ { "id": "Q9VUM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUM2" } ] }, { "name": "Romo1", "type": "synonym", "evidence": [ { "id": "NP_648757", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648757" }, { "id": "Q9VUM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUM2" } ] } ], "protein_names": [ { "name": "Reactive oxygen species modulator 1", "type": "recommended", "evidence": [ { "id": "Q9VUM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUM2/entry#names_and_taxonomy" } ] }, { "name": "CG6878-PA", "type": "synonym", "evidence": [ { "id": "NP_648757", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648757" } ] }, { "name": "Protein MGR2 homolog", "type": "synonym", "evidence": [ { "id": "Q9VUM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUM2/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_648757", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648757" } ] } ], "function": [ { "annotation": "Has antibacterial activity against a variety of bacteria including S.aureus, P.aeruginosa and M.tuberculosis. Acts by inducing bacterial membrane breakage.", "evidence": [ { "database": "UniProtKB", "id": "Q9VUM2", "url": "https://www.uniprot.org/uniprotkb/Q9VUM2#function" }, { "database": "UniProtKB", "id": "ARBA00025225", "url": "https://www.uniprot.org/uniprotkb/ARBA00025225#function" } ] }, { "annotation": "Induces production of reactive oxygen species (ROS) which are necessary for cell proliferation. May play a role in inducing oxidative DNA damage and replicative senescence. May play a role in the coordination of mitochondrial morphology and cell proliferation.", "evidence": [ { "database": "UniProtKB", "id": "Q9VUM2", "url": "https://www.uniprot.org/uniprotkb/Q9VUM2#function" }, { "database": "UniProtKB", "id": "ARBA00025243", "url": "https://www.uniprot.org/uniprotkb/ARBA00025243#function" } ] } ], "disease": [ { "disease_id": "DOID:5199", "recommended_name": { "id": "DOID:5199", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5199", "name": "ureteral obstruction", "description": "An urinary tract obstruction that is characterized by a blockage in one or both of the tubes (ureters) that carry urine from the kidneys to the bladder." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "5199", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5199" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VUM2", "url": "https://www.uniprot.org/uniprotkb/Q9VUM2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG6878", "url": "https://www.uniprot.org/uniprotkb/Q9VUM2", "locus": { "chromosome": "3L", "start_pos": 15162470, "end_pos": 15161817, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0036488", "url": "https://www.ensemblgenomes.org/id/FBgn0036488" } ] } } ], "crossref": [ { "id": "FB:FBgn0036488", "url": "https://alliancegenome.org/gene/FB:FBgn0036488", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0036488", "url": "https://bgee.org/?page=gene&gene_id=FBgn0036488", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0036488", "url": "https://flybase.org/reports/FBgn0036488", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "39656", "url": "https://www.ncbi.nlm.nih.gov/gene/39656", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VUM2", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VUM2*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR018450", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018450", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG6878", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG6878", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SCWDRVK", "url": "https://omabrowser.org/oma/group/SCWDRVK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VUM2", "url": "https://www.orthodb.org/?gene=Q9VUM2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28525", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28525", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28525:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28525:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10247", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10247", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_648757", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648757", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VUM2", "url": "https://www.uniprot.org/uniprotkb/Q9VUM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VUM2-1", "url": "https://www.uniprot.org/uniprotkb/Q9VUM2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPLPTSSFSQQGPTCFDKMKTGFIIGFCVGMASGAVFGGFSALRYGLRGRELINNVGKTMVQGGGTFGTFMAIGTGIRC", "length": 79, "header": "tr|Q9VUM2-1|Q9VUM2_DROME Isoform 1 of Reactive oxygen species modulator 1 OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG6878 PE=1 SV=1 CANONICAL=Q9VUM2-1" }, "isoforms": [ { "isoform_ac": "Q9VUM2-1", "url": "https://www.uniprot.org/uniprotkb/Q9VUM2/entry#Q9VUM2-1", "sequence": { "sequence": "MPLPTSSFSQQGPTCFDKMKTGFIIGFCVGMASGAVFGGFSALRYGLRGRELINNVGKTMVQGGGTFGTFMAIGTGIRC", "length": 79, "header": "tr|Q9VUM2-1|Q9VUM2_DROME Isoform 1 of Reactive oxygen species modulator 1 OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG6878 PE=1 SV=1 CANONICAL=Q9VUM2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VUM2", "url": "https://www.uniprot.org/uniprotkb/Q9VUM2" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VUM2", "url": "https://www.uniprot.org/uniprotkb/Q9VUM2" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUM2", "url": "https://www.uniprot.org/uniprotkb/Q9VUM2" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUM2", "url": "https://www.uniprot.org/uniprotkb/Q9VUM2" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VUM2", "url": "https://www.uniprot.org/uniprotkb/Q9VUM2" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VUM2", "url": "https://www.uniprot.org/uniprotkb/Q9VUM2" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VUM2", "url": "https://www.uniprot.org/uniprotkb/Q9VUM2" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUM2", "url": "https://www.uniprot.org/uniprotkb/Q9VUM2" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUM2", "url": "https://www.uniprot.org/uniprotkb/Q9VUM2" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VUM2", "url": "https://www.uniprot.org/uniprotkb/Q9VUM2" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VUM2", "url": "https://www.uniprot.org/uniprotkb/Q9VUM2" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG6878", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG6878", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1TBQ2-1", "protein_name": "Reactive oxygen species modulator 1", "gene_name": "ROMO1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPVAVGPYGQSQPSCFDRVKMGFVMGCAVGMAAGALFGTFSCLRIGMRGRELMGGIGKTMMQSGGTFGTFMAIGMGIRC", "length": 79 }, "evidence": [ { "id": "Q9VUM2", "url": "https://omabrowser.org/oma/group/Q9VUM2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D4A742-1", "protein_name": "Reactive oxygen species modulator 1", "gene_name": "Romo1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPVAVGPYGQSQPSCFDRVKMGFVMGCAVGMAAGALFGTFSCLRIGMRGRELMGGIGKTMMQSGGTFGTFMAIGMGIRC", "length": 79 }, "evidence": [ { "id": "RGD:1587111", "url": "https://alliancegenome.org/gene/RGD:1587111#orthology", "database": "AGR" }, { "id": "MGI:1914317", "url": "https://alliancegenome.org/gene/MGI:1914317#orthology", "database": "AGR" }, { "id": "HGNC:16185", "url": "https://alliancegenome.org/gene/HGNC:16185#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1768", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1768#orthology", "database": "AGR" }, { "id": "FB:FBgn0036488", "url": "https://alliancegenome.org/gene/FB:FBgn0036488#orthology", "database": "AGR" }, { "id": "SGD:S000006019", "url": "https://alliancegenome.org/gene/SGD:S000006019#orthology", "database": "AGR" }, { "id": "Q9VUM2", "url": "https://omabrowser.org/oma/group/Q9VUM2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HAR5-1", "protein_name": "Reactive oxygen species modulator 1", "gene_name": "Romo1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPVAVGPYGQSQPSCFDRVKMGFVMGCAVGMAAGALFGTFSCLRIGMRGRELMGGIGKTMMQSGGTFGTFMAIGMGIRC", "length": 79 }, "evidence": [ { "id": "Q9VUM2", "url": "https://omabrowser.org/oma/group/Q9VUM2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P60602-1", "protein_name": "Reactive oxygen species modulator 1", "gene_name": "ROMO1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPVAVGPYGQSQPSCFDRVKMGFVMGCAVGMAAGALFGTFSCLRIGMRGRELMGGIGKTMMQSGGTFGTFMAIGMGIRC", "length": 79 }, "evidence": [ { "id": "RGD:1587111", "url": "https://alliancegenome.org/gene/RGD:1587111#orthology", "database": "AGR" }, { "id": "MGI:1914317", "url": "https://alliancegenome.org/gene/MGI:1914317#orthology", "database": "AGR" }, { "id": "HGNC:16185", "url": "https://alliancegenome.org/gene/HGNC:16185#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1768", "url": 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from those that affect the patient's personality to those that cause a decline in cognitive function." }, "synonyms": [ { "id": "DOID:11870", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11870", "name": "Dementia in Pick's disease", "description": "" }, { "id": "DOID:11870", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11870", "name": "LOBAR ATROPHY OF BRAIN", "description": "" }, { "id": "DOID:11870", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11870", "name": "PICK DISEASE OF BRAIN", "description": "" }, { "id": "DOID:11870", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11870", "name": "Pick disease", "description": "" }, { "id": "MONDO:0008243", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008243", "name": "Pick disease", "description": "A rare neurodegenerative disorder leading to dementia. It is characterized by frontotemporal lobar degeneration with accumulation of tau proteins which form Pick bodies." }, { "id": "MONDO:0008243", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008243", "name": "PICK disease of brain", "description": "" }, { "id": "MONDO:0008243", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008243", "name": "Pick disease", "description": "" }, { "id": "MONDO:0008243", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008243", "name": "lobar atrophy of brain", "description": "" }, { "id": "MONDO:0008243", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008243", "name": "Pick disease of the brain", "description": "" }, { "id": "MONDO:0008243", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008243", "name": "lobar atrophy of the brain", "description": "" }, { "id": "MIM:172700", "resource": "MIM", "url": "https://www.omim.org/entry/172700", "name": "Pick disease of the brain", "description": "Pick disease of the brain" } ], "unlinked_id_list": [], "evidence": [ { "id": "11870", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11870" } ] }, { "disease_id": "DOID:12217", "recommended_name": { "id": "DOID:12217", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12217", "name": "Lewy body dementia", "description": "A dementia that is characterized by the development of abnormal proteinaceous (alpha-synuclein) cytoplasmic inclusions, called Lewy bodies, throughout the brain that results in progressive decline in mental abilities that has_material_basis_in accumulation of alpha-synuclein, SCNA, (protein). The causal mutation might be in SCNA or SCNB or some other gene(s) but the end result is always accumulation of SCNA in Lewy bodies." }, "synonyms": [ { "id": "DOID:12217", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12217", "name": "Dementia with Lewy bodies", "description": "" }, { "id": "DOID:12217", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12217", "name": "Diffuse Lewy body disease", "description": "" }, { "id": "DOID:12217", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12217", "name": "Lewy body disease", "description": "" }, { "id": "DOID:12217", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12217", "name": "Senile dementia of the Lewy body type", "description": "" }, { "id": "MONDO:0007488", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007488", "name": "Lewy body dementia", "description": "A progressive form of dementia characterized by the presence of protein deposits called Lewy bodies in the midbrain and cerebral cortex, and loss of cholinergic and dopaminergic neurons. The signs and symptoms overlap with Alzheimer and Parkinson disease." }, { "id": "MONDO:0007488", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007488", "name": "DLB", "description": "" }, { "id": "MONDO:0007488", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007488", "name": "Lewy body dementia", "description": "" }, { "id": "MONDO:0007488", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007488", "name": "Lewy body disease", "description": "" }, { "id": "MONDO:0007488", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007488", "name": "cortical Lewy body disease", "description": "" }, { "id": "MONDO:0007488", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007488", "name": "dementia with Lewy bodies", "description": "" }, { "id": "MONDO:0007488", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007488", "name": "lewy body dementia, susceptibility to", "description": "" }, { "id": "MONDO:0007488", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007488", "name": "dementia, Lewy body", "description": "" }, { "id": "MIM:127750", "resource": "MIM", "url": "https://www.omim.org/entry/127750", "name": "Dementia, Lewy body", "description": "Dementia, Lewy body" } ], "unlinked_id_list": [], "evidence": [ { "id": "12217", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12217" } ] }, { "disease_id": "DOID:14330", "recommended_name": { "id": "DOID:14330", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions." }, "synonyms": [ { "id": "DOID:14330", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14330", "name": "Parkinson disease", "description": "" }, { "id": "DOID:14330", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14330", "name": "paralysis agitans", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "late-onset Parkinson disease", "description": "A Parkinson disease that begins after around the age of 50." }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "LOPD", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "PARK", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "PD", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "Parkinson disease, age of onset, modifier, Multifactorial", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "Parkinson disease, late-onset", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "Parkinson disease, late-onset, susceptibility to, Multifactorial", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "Parkinson disease, susceptibility to, Multifactorial", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "autosomal dominant late-onset Parkinson disease", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "hereditary late onset Parkinson disease", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "hereditary late-onset Parkinson disease", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "late-onset Parkinson disease", "description": "" }, { "id": "MIM:168600", "resource": "MIM", "url": "https://www.omim.org/entry/168600", "name": "Parkinson disease", "description": "Parkinson disease" } ], "unlinked_id_list": [], "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ] }, { "disease_id": "DOID:231", "recommended_name": { "id": "DOID:231", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:231", "name": "motor neuron disease", "description": "A neurodegenerative disease that is located_in the motor neurons." }, "synonyms": [], "unlinked_id_list": [ "DOID:681" ], "evidence": [ { "id": "231", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:231" } ] }, { "disease_id": "DOID:332", "recommended_name": { "id": "DOID:332", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:332", "name": "amyotrophic lateral sclerosis", "description": "A motor neuron disease that is characterized by muscle spasticity, rapidly progressive weakness due to muscle atrophy, difficulty in speaking, swallowing, and breathing." }, "synonyms": [ { "id": "DOID:332", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:332", "name": "ALS", "description": "" }, { "id": "DOID:332", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:332", "name": "Lou Gehrig's disease", "description": "" }, { "id": "DOID:332", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:332", "name": "motor neuron disease, bulbar", "description": "" }, { "id": "MONDO:0007103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007103", "name": "amyotrophic lateral sclerosis type 1", "description": "" }, { "id": "MONDO:0007103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007103", "name": "ALS1", "description": "" }, { "id": "MONDO:0007103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007103", "name": "amyotrophic lateral sclerosis 1", "description": "" }, { "id": "MONDO:0007103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007103", "name": "amyotrophic lateral sclerosis type 1", "description": "" }, { "id": "MONDO:0007103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007103", "name": "FALS", "description": "" }, { "id": "MONDO:0007103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007103", "name": "amyotrophic lateral sclerosis 1, autosomal dominant amyotrophic lateral sclerosis 1, autosomal recessive, included", "description": "" }, { "id": "MONDO:0007103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007103", "name": "amyotrophic lateral sclerosis 1, familial", "description": "" }, { "id": "MONDO:0007103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007103", "name": "amyotrophic lateral sclerosis, autosomal dominant", "description": "" }, { "id": "MONDO:0007103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007103", "name": "amyotrophic lateral sclerosis, familial", "description": "" }, { "id": "MONDO:0007103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007103", "name": "amyotrophic lateral sclerosis, sporadic", "description": "" }, { "id": "MONDO:0007103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007103", "name": "amyotrophic lateral sclerosis, sporadic, included", "description": "" }, { "id": "MIM:105400", "resource": "MIM", "url": "https://www.omim.org/entry/105400", "name": "Amyotrophic lateral sclerosis 1", "description": "Amyotrophic lateral sclerosis 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "332", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:332" } ] }, { "disease_id": "DOID:678", "recommended_name": { "id": "DOID:678", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:678", "name": "progressive supranuclear palsy", "description": "A movement disease that is characterized by serious and progressive problems with control of gait and balance, along with complex eye movement and thinking problems. It involves gradual deterioration and death of specific volumes of the brain." }, "synonyms": [ { "id": "DOID:678", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:678", "name": "Steele-Richardson-Olszewski syndrome", "description": "" }, { "id": "DOID:678", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:678", "name": "progressive supranuclear ophthalmoplegia", "description": "" }, { "id": "MONDO:0010997", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010997", "name": "supranuclear palsy, progressive, 1", "description": "Classical progressive supranuclear palsy, also known as Richardson's syndrome, is the most common clinical variant of progressive supranuclear palsy (PSP), a rare late-onset neurodegenerative disease characterized by postural instability, progressive rigidity, supranuclear gaze palsy and mild dementia." }, { "id": "MONDO:0010997", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010997", "name": "Steele-Richardson-Olszewski disease", "description": "" }, { "id": "MONDO:0010997", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010997", "name": "Steele-Richardson-Olszewski syndrome", "description": "" }, { "id": "MONDO:0010997", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010997", "name": "PSP", "description": "" }, { "id": "MONDO:0010997", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010997", "name": "Richardson syndrome", "description": "" }, { "id": "MONDO:0010997", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010997", "name": "classic PSP syndrome", "description": "" }, { "id": "MONDO:0010997", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010997", "name": "classic progressive supranuclear palsy syndrome", "description": "" }, { "id": "MONDO:0010997", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010997", "name": "supranuclear palsy, progressive", "description": "" }, { "id": "MONDO:0010997", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010997", "name": "supranuclear palsy, progressive, 1", "description": "" }, { "id": "MONDO:0010997", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010997", "name": "supranuclear palsy, progressive, type 1", "description": "" }, { "id": "MONDO:0010997", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010997", "name": "PSNP1", "description": "" }, { "id": "MONDO:0012278", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012278", "name": "supranuclear palsy, progressive, 2", "description": "" }, { "id": "MONDO:0012278", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012278", "name": "PSNP2", "description": "" }, { "id": "MONDO:0012278", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012278", "name": "supranuclear palsy, progressive, 2", "description": "" }, { "id": "MONDO:0012576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012576", "name": "supranuclear palsy, progressive, 3", "description": "" }, { "id": "MONDO:0012576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012576", "name": "PSNP3", "description": "" }, { "id": "MONDO:0012576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012576", "name": "supranuclear palsy, progressive, 3", "description": "" }, { "id": "MIM:601104", "resource": "MIM", "url": "https://www.omim.org/entry/601104", "name": "Progressive supranuclear palsy 1", "description": "Progressive supranuclear palsy 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "678", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:678" } ] }, { "disease_id": "DOID:9255", "recommended_name": { "id": "DOID:9255", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9255", "name": "frontotemporal dementia", "description": "A dementia characterized by progressive neuronal loss predominantly involving the frontal and/or temporal lobes of the brain resulting in a gradual and progressive decline in behavior or language." }, "synonyms": [ { "id": "DOID:9255", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9255", "name": "Wilhemsen-Lynch disease", "description": "" }, { "id": "DOID:9255", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9255", "name": "frontotemporal lobar degeneration", "description": "" }, { "id": "DOID:9255", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9255", "name": "multiple system tauopathy with presenile dementia", "description": "" }, { "id": "DOID:9255", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9255", "name": "pallidopontonigral degeneration", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "9255", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9255" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VUN2", "url": "https://www.uniprot.org/uniprotkb/Q9VUN2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "cocoon", "url": "https://www.uniprot.org/uniprotkb/Q9VUN2", "locus": { "chromosome": "3L", "start_pos": 15472197, "end_pos": 15474110, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0036496", "url": "https://www.ensemblgenomes.org/id/FBgn0036496" } ] } } ], "crossref": [ { "id": "FB:FBgn0036496", "url": "https://alliancegenome.org/gene/FB:FBgn0036496", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0036496", "url": "https://bgee.org/?page=gene&gene_id=FBgn0036496", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12321", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12321", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12322", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12322", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19609", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19609", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0036496", "url": "https://flybase.org/reports/FBgn0036496", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "39665", "url": "https://www.ncbi.nlm.nih.gov/gene/39665", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041105", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041105", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG7804", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG7804", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NNFNMHP", "url": "https://omabrowser.org/oma/group/NNFNMHP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VUN2", "url": "https://www.orthodb.org/?gene=Q9VUN2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48033", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48033", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48033:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48033:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18694", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18694", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001261874", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261874", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VUN2", "url": "https://www.uniprot.org/uniprotkb/Q9VUN2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VUN2-1", "url": "https://www.uniprot.org/uniprotkb/Q9VUN2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVFVHVSEKEGDEPIELPAEEDGTLLLSTLQAQFPESSGLQYRNVDTKAVRGVRSNEGRLYSPSEETGWGEYHYFCVFPKKNKRQSEDNLENSTAKTKRTEAHLRCFDLIVLGLSYNTTEQDLREYFETYGDVVKAEIKKDTRSGHSKGFGFVRFGSYDVQMHVLSKRHSIDGRWCEVKVPASRGMGNQEPGKVFVGRCTEDIEADDLREYFSKFGEVIDVFIPKPFRAFSFVTFLDPYVPRVVCGEKHIIKGVSVHVSTADKKNVQNKNQLFQTNNYNNLDNNFKMQPANNFRMHPANNFSMHSFNPHGYQMNRVMN", "length": 318, "header": "tr|Q9VUN2-1|Q9VUN2_DROME Isoform 1 of TAR DNA-binding protein 43 OS=Drosophila melanogaster OX=7227 GN=cocoon PE=4 SV=2 CANONICAL=Q9VUN2-1" }, "isoforms": [ { "isoform_ac": "Q9VUN2-1", "url": "https://www.uniprot.org/uniprotkb/Q9VUN2/entry#Q9VUN2-1", "sequence": { "sequence": "MVFVHVSEKEGDEPIELPAEEDGTLLLSTLQAQFPESSGLQYRNVDTKAVRGVRSNEGRLYSPSEETGWGEYHYFCVFPKKNKRQSEDNLENSTAKTKRTEAHLRCFDLIVLGLSYNTTEQDLREYFETYGDVVKAEIKKDTRSGHSKGFGFVRFGSYDVQMHVLSKRHSIDGRWCEVKVPASRGMGNQEPGKVFVGRCTEDIEADDLREYFSKFGEVIDVFIPKPFRAFSFVTFLDPYVPRVVCGEKHIIKGVSVHVSTADKKNVQNKNQLFQTNNYNNLDNNFKMQPANNFRMHPANNFSMHSFNPHGYQMNRVMN", "length": 318, "header": "tr|Q9VUN2-1|Q9VUN2_DROME Isoform 1 of TAR DNA-binding protein 43 OS=Drosophila melanogaster OX=7227 GN=cocoon PE=4 SV=2 CANONICAL=Q9VUN2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VUN2", "url": "https://www.uniprot.org/uniprotkb/Q9VUN2" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VUN2", "url": "https://www.uniprot.org/uniprotkb/Q9VUN2" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUN2", "url": "https://www.uniprot.org/uniprotkb/Q9VUN2" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUN2", "url": "https://www.uniprot.org/uniprotkb/Q9VUN2" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VUN2", "url": "https://www.uniprot.org/uniprotkb/Q9VUN2" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VUN2", "url": "https://www.uniprot.org/uniprotkb/Q9VUN2" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VUN2", "url": "https://www.uniprot.org/uniprotkb/Q9VUN2" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUN2", "url": "https://www.uniprot.org/uniprotkb/Q9VUN2" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUN2", "url": "https://www.uniprot.org/uniprotkb/Q9VUN2" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VUN2", "url": "https://www.uniprot.org/uniprotkb/Q9VUN2" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VUN2", "url": "https://www.uniprot.org/uniprotkb/Q9VUN2" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG7804", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG7804", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6GLU8-1", "protein_name": "TAR DNA-binding protein 43", "gene_name": "Tardbp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEGILHAPDAGWGNLVYVVNYPKDNKRKMDEADASSAVKVKRAVQKTSDLIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNSKQSPDEPLRSRKVFVGRCTEDMTAEELQQFFCQYGEVVDVFIPKPFRAFAFVTFADDKVAQSLCGEDLIIKGISVHISNAEPKHNSNRQLERSGRFGGNPGGFGNQGGFGNSRGGGAGLGNNQGGNMGGGMNFGAFSINPAMMAAAQAALQSSWGMMGMLASQQNQSGPSGNNQSQGSMQREPNQAFGSGNNSYSGSNSGAPLGWGSASNAGSGSGFNGGFGSSMDSKSSGWGM", "length": 414 }, "evidence": [ { "id": "MGI:2387629", "url": "https://alliancegenome.org/gene/MGI:2387629#orthology", "database": "AGR" }, { "id": "HGNC:11571", "url": "https://alliancegenome.org/gene/HGNC:11571#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-031030-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-031030-1#orthology", "database": "AGR" }, { "id": "RGD:1310906", "url": "https://alliancegenome.org/gene/RGD:1310906#orthology", "database": "AGR" }, { "id": "FB:FBgn0036496", "url": "https://alliancegenome.org/gene/FB:FBgn0036496#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AC58IJ45-1", "protein_name": "TAR DNA-binding protein 43", "gene_name": "tardbpa", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTECYIRVAEDENEEPMEIPSEEDGTVLLSTVAAQFPGACGLRYRSPVSQCMRGVRLVEGVLHAPEADWGNLVYVVNYPKDNKRKMDEMDAASAVKIKRGIQKTSDLIVLGLPWKTTEQDLKDYFGTFGEVIMVQVKRDAKSGNSKGFGFVRFTDYETQIKVMSQRHMIDGRWCDCKLPNSKYFLEQAGPDEPMRSRKVFVGRCTEDMTADELRQFFMQYGEVTDVFIPKPFRAFAFVTFADDQVAQSLCGEDLIIKGTSVHISNAEPKHNNSRQMMDRGRFGGYGGQGFGSSRSPNSNVNFGALNLNPAMMAAAQAALQSSWGMMGMLANQQNQTPASGTNPSGQSGSRDQTQNYSASSNNYNAGSSAALGWGAGTNSAAAGGFNSSFGSSMETKSSWGM", "length": 401 }, "evidence": [ { "id": "MGI:2387629", "url": "https://alliancegenome.org/gene/MGI:2387629#orthology", "database": "AGR" }, { "id": "HGNC:11571", "url": "https://alliancegenome.org/gene/HGNC:11571#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-031030-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-031030-1#orthology", "database": "AGR" }, { "id": "RGD:1310906", "url": "https://alliancegenome.org/gene/RGD:1310906#orthology", "database": "AGR" }, { "id": "FB:FBgn0036496", "url": "https://alliancegenome.org/gene/FB:FBgn0036496#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q13148-1", "protein_name": "TAR DNA-binding protein 43", "gene_name": "TARDBP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEGILHAPDAGWGNLVYVVNYPKDNKRKMDETDASSAVKVKRAVQKTSDLIVLGLPWKTTEQDLKEYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNSKQSQDEPLRSRKVFVGRCTEDMTEDELREFFSQYGDVMDVFIPKPFRAFAFVTFADDQIAQSLCGEDLIIKGISVHISNAEPKHNSNRQLERSGRFGGNPGGFGNQGGFGNSRGGGAGLGNNQGSNMGGGMNFGAFSINPAMMAAAQAALQSSWGMMGMLASQQNQSGPSGNNQNQGNMQREPNQAFGSGNNSYSGSNSGAAIGWGSASNAGSGSGFNGGFGSSMDSKSSGWGM", "length": 414 }, "evidence": [ { "id": "MGI:2387629", "url": "https://alliancegenome.org/gene/MGI:2387629#orthology", "database": "AGR" }, { "id": "HGNC:11571", "url": "https://alliancegenome.org/gene/HGNC:11571#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-031030-1", "url": 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"MSEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGACGLRYRNPVSQCMRGVRLVEGILHAPDAGWGNLVYVVNYPKDNKRKMDETDASSAVKVKRAVQKTSDLIVLGLPWKTTEQDLKDYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYETQVKVMSQRHMIDGRWCDCKLPNSKQSPDEPLRSRKVFVGRCTEDMTAEELQQFFCQYGEVVDVFIPKPFRAFAFVTFADDKVAQSLCGEDLIIKGISVHISNAEPKHNSNRQLERSGRFGGNPGGFGNQGGFGNSRGGGAGLGNNQGGNMGGGMNFGAFSINPAMMAAAQAALQSSWGMMGMLASQQNQSGPSGNNQSQGSMQREPNQAFGSGNNSYSGSNSGAPLGWGSASNAGSGSGFNGGFGSSMDSKSSGWGM", "length": 414 }, "evidence": [ { "id": "MGI:2387629", "url": "https://alliancegenome.org/gene/MGI:2387629#orthology", "database": "AGR" }, { "id": "HGNC:11571", "url": "https://alliancegenome.org/gene/HGNC:11571#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-031030-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-031030-1#orthology", "database": "AGR" }, { "id": "RGD:1310906", "url": "https://alliancegenome.org/gene/RGD:1310906#orthology", "database": "AGR" }, { "id": "FB:FBgn0036496", "url": "https://alliancegenome.org/gene/FB:FBgn0036496#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q9VUN2", "url": "https://www.uniprot.org/uniprotkb/Q9VUN2" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "Q9VUN2", "url": "https://www.uniprot.org/uniprotkb/Q9VUN2" } ], "pmid": "" }, { "name": "double-stranded DNA binding", "id": "GO:0003690", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003690", "evidence": [ { "database": "UniProtKB", "id": "Q9VUN2", "url": "https://www.uniprot.org/uniprotkb/Q9VUN2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q9VUN2", "url": "https://www.uniprot.org/uniprotkb/Q9VUN2" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9VUN2", "url": "https://www.uniprot.org/uniprotkb/Q9VUN2" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "Q9VUN2", "url": "https://www.uniprot.org/uniprotkb/Q9VUN2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q9VUN2", "url": "https://www.uniprot.org/uniprotkb/Q9VUN2" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": 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RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, 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"url": "https://www.uniprot.org/uniprotkb/Q9VUN7" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VUN7", "url": "https://www.uniprot.org/uniprotkb/Q9VUN7" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUN7", "url": "https://www.uniprot.org/uniprotkb/Q9VUN7" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUN7", "url": "https://www.uniprot.org/uniprotkb/Q9VUN7" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VUN7", "url": "https://www.uniprot.org/uniprotkb/Q9VUN7" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VUN7", "url": "https://www.uniprot.org/uniprotkb/Q9VUN7" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VUN7", "url": "https://www.uniprot.org/uniprotkb/Q9VUN7" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUN7", "url": "https://www.uniprot.org/uniprotkb/Q9VUN7" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUN7", "url": "https://www.uniprot.org/uniprotkb/Q9VUN7" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VUN7", "url": "https://www.uniprot.org/uniprotkb/Q9VUN7" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VUN7", "url": "https://www.uniprot.org/uniprotkb/Q9VUN7" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG7275", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG7275", "resource": "KEGG Pathway" }, { "id": "R-DME-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" }, { "id": "R-DME-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8951664", "resource": "Reactome", "description": "Neddylation" } ], "orthologs": [ { "uniprot_canonical_ac": "F1M7P1-1", "protein_name": "DDB1- and CUL4-associated factor 13", "gene_name": "Dcaf13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKVKMLSRNPDNYVRETKLDIQRVPRNYDPTLHPFEVPREYVRALNATKLERVFAKPFLASLDGHRDGVNCLAKHPKSLATVLSGACDGEVKIWNLTKRKCIRTIQAHEGFVRGICTRFCGTSFFTVGDDKTVKQWKMDGPGCGEEEEPLYTVLGKTVYTGIDHHWKDPAFATCGQQVDIWDEQRTSPVCSMNWGFDSISSVKFNPIETYLLGSCASDRNIVLYDMRQATPLKKVILDMRTNTICWNPMEAFNFTAANEDYNLYTFDMRALDTPVMVHLDHVSAVLDVDYSPTGKEFVSASFDKSIRIFPVDKSRSREVYHTRRMQHVICVKWTSDSKYILCGSDEMNIRLWKANASEKLGVLTSRERAANDYNQKLKEKFQYHPHVKRIARHRHLPKSIYSQIQEQRVMKEARRRKEMNRRKHSKPGSVPVVSERKKHVVAVVK", "length": 445 }, "evidence": [ { "id": "RGD:1308458", "url": "https://alliancegenome.org/gene/RGD:1308458#orthology", "database": "AGR" }, { "id": "MGI:2684929", "url": "https://alliancegenome.org/gene/MGI:2684929#orthology", "database": "AGR" }, { "id": "HGNC:24535", "url": "https://alliancegenome.org/gene/HGNC:24535#orthology", "database": "AGR" }, { "id": "FB:FBgn0036500", "url": "https://alliancegenome.org/gene/FB:FBgn0036500#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-703", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-703#orthology", "database": "AGR" }, { "id": "SGD:S000003934", "url": "https://alliancegenome.org/gene/SGD:S000003934#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MVI8-1", "protein_name": "DDB1- and CUL4-associated factor 13", "gene_name": "DCAF13", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKVKMLSRNPDHYVRETKLDLQRVPRNYDPTLHPFEVPREYIRALNATKLERVFAKPFLASLDGHRDGVNCLAKNPKSLATVLSGACDGEVKIWNLTKRKCIRTIQAHEGFVRGICTRFCGTSFFTVGDDKTVKQWKMDGPSCGEEEEPLHTILGKTVYTGIDHHWREAVFATCGQQVDIWDEQRTSPICSMTWGFDSISSVKFNPIETFLLGSCASDRNIVLYDMRQATPLKKVILDMRTNTICWNPMEAFIFTAANEDYNLYTFDMRALDTPVMVHMDHVSAVLDVDYSPTGREFVSASFDKSIRIFPVDKSRSREVYHTKRMQHVICVKWTADSKYIMCGSDEMNIRLWKANASEKLGVLTSRERAATDYNQKLKEKFQHHPHIKRISRHRHLPKSIYSQIQEQRIMKEARRRKELNRIKHSKPGSVQMVSEKKKHVVAVVK", "length": 445 }, "evidence": [ { "id": "Q9VUN7", "url": "https://omabrowser.org/oma/group/Q9VUN7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P33750-1", "protein_name": "Protein SOF1", "gene_name": "SOF1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MKIKTIKRSADDYVPVKSTQESQMPRNLNPELHPFERAREYTKALNATKLERMFAKPFVGQLGYGHRDGVYAIAKNYGSLNKLATGSADGVIKYWNMSTREEFVSFKAHYGLVTGLCVTQPRFHDKKPDLKSQNFMLSCSDDKTVKLWSINVDDYSNKNSSDNDSVTNEEGLIRTFDGESAFQGIDSHRENSTFATGGAKIHLWDVNRLKPVSDLSWGADNITSLKFNQNETDILASTGSDNSIVLYDLRTNSPTQKIVQTMRTNAICWNPMEAFNFVTANEDHNAYYYDMRNLSRSLNVFKDHVSAVMDVDFSPTGDEIVTGSYDKSIRIYKTNHGHSREIYHTKRMQHVFQVKYSMDSKYIISGSDDGNVRLWRSKAWERSNVKTTREKNKLEYDEKLKERFRHMPEIKRISRHRHVPQVIKKAQEIKNIELSSIKRREANERRTRKDMPYISERKKQIVGTVHKYEDSGRDRKRRKEDDKRDTQEK", "length": 489 }, "evidence": [ { "id": "RGD:1308458", "url": "https://alliancegenome.org/gene/RGD:1308458#orthology", "database": "AGR" }, { "id": "MGI:2684929", "url": "https://alliancegenome.org/gene/MGI:2684929#orthology", "database": "AGR" }, { "id": "HGNC:24535", "url": "https://alliancegenome.org/gene/HGNC:24535#orthology", "database": "AGR" }, { "id": "FB:FBgn0036500", "url": "https://alliancegenome.org/gene/FB:FBgn0036500#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-703", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-703#orthology", "database": "AGR" }, { "id": "SGD:S000003934", "url": "https://alliancegenome.org/gene/SGD:S000003934#orthology", "database": "AGR" }, { "id": "Q9VUN7", "url": "https://omabrowser.org/oma/group/Q9VUN7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q5ZLK1-1", "protein_name": "DDB1- and CUL4-associated factor 13", "gene_name": "DCAF13", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRVKVLSRNPDDYVRETKLDLQRVPRNYDPALHPFEVAREYVRALNATKLERVFAKPFLSSLDGHRDGVNCMAKHPKSLSTVLSGACDGEVRIWNLTKRQCIRALQAHEGFVRGMCARFCGTSFFTVGDDKTVKQWKMESPGYGEEEEPIHTILGKTVYTGIDHHWKDAVFATCGQQVDIWDEQRTSPMCSLTWGFDSISSVKFNPIETYLLGSCASDRNIVLYDMRQSTPLKKVILNMRTNTLCWNPMEAFIFTAANEDYNLYTFDMRFLTSPVMVHMDHVSAVLDVDYSPTGKEFVSASFDKSVRIFPVDKGHSREVYHTKRMQHVITVKWTSDSRYILCGSDEMNIRLWKANASEKLGVLAPREKAAMNYNQKLKEKFQHHPQIKRIARHRHLPKSIYCQIKEQRIMREARRRKELNRRKHSKPGSVPVVSEKKKHIVAVVQ", "length": 445 }, "evidence": [ { "id": "Q9VUN7", "url": "https://omabrowser.org/oma/group/Q9VUN7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q6PAC3-1", "protein_name": "DDB1- and CUL4-associated factor 13", "gene_name": "Dcaf13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKVKMLSRNPDNYVRETKLDIQRVPRNYDPTLHPFEVPREYVRALNATKLERVFAKPFLASLDGHRDGVNCLAKHPKSLASVLSGACDGEVKIWNLTKRKCIRTIQAHEGFVRGMCTRFCGTSFFTVGDDKTVKQWKMDGPGYGEEEEPLYTVLGKTVYTGIDHHWKDPVFATCGQQVDIWDEQRTSPVCSMNWGFDSISSVKFNPVETFLLGSCASDRNIVLYDMRQATPLKKVILEMRTNTICWNPMEAFNFTAANEDYNLYTFDMRALDTPVMVHMDHVSAVLDVDYSPTGKEFVSASFDKSIRIFPVDKSRSREVYHTKRMQHVMCVKWTSDSKYIMCGSDEMNIRLWKANASEKLGVLTSREKAANDYNQKLKEKFQYHPHVKRIARHRHLPKSIYSQIQEQRVMKEARRRKEMNRRKHSKPGSVPIVSERKKHVVAVVK", "length": 445 }, "evidence": [ { "id": "RGD:1308458", "url": "https://alliancegenome.org/gene/RGD:1308458#orthology", "database": "AGR" }, { "id": "MGI:2684929", "url": "https://alliancegenome.org/gene/MGI:2684929#orthology", "database": "AGR" }, { "id": "HGNC:24535", "url": "https://alliancegenome.org/gene/HGNC:24535#orthology", "database": "AGR" }, { "id": "FB:FBgn0036500", "url": "https://alliancegenome.org/gene/FB:FBgn0036500#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-703", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-703#orthology", "database": "AGR" }, { "id": "SGD:S000003934", "url": "https://alliancegenome.org/gene/SGD:S000003934#orthology", "database": "AGR" }, { "id": "Q9VUN7", "url": "https://omabrowser.org/oma/group/Q9VUN7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7KWL3-1", "protein_name": "DDB1- and CUL4-associated factor 13", "gene_name": "wdsof1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKIKVISRSEEEETKEKASDVRKLHRNLDPNLHPFERPREYVRALNATKLDRVFAKPFIGSLSGHTDGIFTMTRHPTLLNNVASGSCDGVIKLWNLTSLTERTTVQAHNGFVRGLVFTPDGKHMVSCGEDKTIKMWKLDLPEYTFNQEVISIYNGKNAFTSIDHQLNSTTFATSGPTSVEIWKHQRSTPIQTLQWGHSTITKVKFNPIETHLLASCTTDRDIILYDIRENSPAQKLTTSMRSNSIAWCPTESFTLAIANEDENVYQYDIRNLSKAMTVHRDHVGSVLDIDYSPTGREIVSGSYDKTIRIFPVDSYKSREVYYTNRMQRIFSVLFTADSRFILSGSDDMNIRVWKANSSAPLGILSNREKEKLEYQDKIKEKFKEIPELKTIATHRRVPQLVYKRRFIKNEIHKAKQRRVKNISNNSGKSPKVEKVLSKHTIKVDN", "length": 445 }, "evidence": [ { "id": "Q9VUN7", "url": "https://omabrowser.org/oma/group/Q9VUN7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q803X4-1", "protein_name": "DDB1- and CUL4-associated factor 13", "gene_name": "dcaf13", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKVKVLCRNPDDYVRETTRDIQRVPRNYDPTLHPFEVPREYTRALNATKLERVFAKPFVASLDGHRDVISCITKHAKSLSTVISGACDGEVKVWNLPKRECTRTVQAHEGFVRGICSRFCGTSFFTVGDDKTIKQWNMEAPGYGVREEPINTILGKAVFTGIDHHQREGTFVTCGQTVDIWDEQRSSPVLSFSWGVDSFSSVRYNPVEPDLLASCASDRSIVLYDTRESAPLRKVIMQLRSNTLCWNPMEAYYFTCANEDYNLYTYDIRNLDVPVTVHMDHVSAVLDVDYSPTGREFVSASFDKTIRIFPKDKGHSREVYHTKRMQHVICVKWSADSKFIMSGSDEMNIRLWKANASEKLGVLSTREKTAANYNKKLIQKFQHHPQVRRIARHRHLPRDVLKQKRELKEMKEARRRKEQNVRKHSKPGSVPLLTEKEKHVVKVVE", "length": 445 }, "evidence": [ { "id": "RGD:1308458", "url": "https://alliancegenome.org/gene/RGD:1308458#orthology", "database": "AGR" }, { "id": "MGI:2684929", "url": "https://alliancegenome.org/gene/MGI:2684929#orthology", "database": "AGR" }, { "id": "HGNC:24535", "url": "https://alliancegenome.org/gene/HGNC:24535#orthology", "database": "AGR" }, { "id": "FB:FBgn0036500", "url": "https://alliancegenome.org/gene/FB:FBgn0036500#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-703", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-703#orthology", "database": "AGR" }, { "id": "SGD:S000003934", "url": "https://alliancegenome.org/gene/SGD:S000003934#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9NV06-1", "protein_name": "DDB1- and CUL4-associated factor 13", "gene_name": "DCAF13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-703#orthology", "database": "AGR" }, { "id": "SGD:S000003934", "url": "https://alliancegenome.org/gene/SGD:S000003934#orthology", "database": "AGR" }, { "id": "Q9VUN7", "url": "https://omabrowser.org/oma/group/Q9VUN7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q9VUN7", "url": "https://www.uniprot.org/uniprotkb/Q9VUN7" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "Q9VUN7", "url": "https://www.uniprot.org/uniprotkb/Q9VUN7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q9VUN7", "url": "https://www.uniprot.org/uniprotkb/Q9VUN7" } ], "pmid": "" }, { "name": "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000462", "evidence": [ { "database": "UniProtKB", "id": "Q9VUN7", "url": "https://www.uniprot.org/uniprotkb/Q9VUN7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 253, "end_pos": 255, "annotation": "n_glycosylation_sequon" }, { "start_pos": 355, "end_pos": 357, "annotation": "n_glycosylation_sequon" }, { "start_pos": 46, "end_pos": 48, "annotation": "n_glycosylation_sequon" }, { "start_pos": 61, "end_pos": 63, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VUN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUN7" }, { "id": "PF04158", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04158" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sof1-like protein", "eco_id": "ECO_0000259", "start_pos": 354, "end_pos": 441, "start_aa": "Ala", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 253, "end_pos": 255 }, { "start_pos": 355, "end_pos": 357 }, { "start_pos": 46, "end_pos": 48 }, { "start_pos": 61, "end_pos": 63 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VUP0-1", "uniprot_ac": "Q9VUP0", "uniprot_id": "Q9VUP0_DROME", "mass": { "chemical_mass": 19514.0, "monoisotopic_mass": 19514.0 }, "refseq": { "ac": "NP_001261876", "name": "uncharacterized protein, isoform B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261876" }, "gene_names": [ { "name": "Dmel\\CG7841", "type": "recommended", "evidence": [ { "id": "Q9VUP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUP0" } ] }, { "name": "CG7841", "type": "synonym", "evidence": [ { "id": "NP_001261876", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261876" }, { "id": "Q9VUP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUP0" } ] }, { "name": "Dmel\\CG7841", "type": "synonym", "evidence": [ { "id": "NP_001261876", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261876" } ] }, { "name": "Dmel_CG7841", "type": "synonym", "evidence": [ { "id": "Q9VUP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUP0" } ] } ], "protein_names": [ { "name": "Protein FAM195A", "type": "recommended", "evidence": [ { "id": "Q9VUP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUP0/entry#names_and_taxonomy" } ] }, { "name": "CG7841-PB", "type": "synonym", "evidence": [ { "id": "NP_001261876", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261876" } ] }, { "name": "uncharacterized protein, isoform B", "type": "synonym", "evidence": [ { "id": "NP_001261876", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261876" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VUP0", "url": "https://www.uniprot.org/uniprotkb/Q9VUP0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG7841", "url": "https://www.uniprot.org/uniprotkb/Q9VUP0", "locus": { "chromosome": "3L", "start_pos": 15505188, "end_pos": 15508252, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0036502", "url": "https://www.ensemblgenomes.org/id/FBgn0036502" } ] } } ], "crossref": [ { "id": "FB:FBgn0036502", "url": "https://alliancegenome.org/gene/FB:FBgn0036502", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0036502", "url": "https://bgee.org/?page=gene&gene_id=FBgn0036502", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0036502", "url": "https://flybase.org/reports/FBgn0036502", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "39672", "url": "https://www.ncbi.nlm.nih.gov/gene/39672", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VUP0", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VUP0*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR029428", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029428", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG7841", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG7841", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YESWNQV", "url": "https://omabrowser.org/oma/group/YESWNQV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VUP0", "url": "https://www.orthodb.org/?gene=Q9VUP0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF14799", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14799", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001261876", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261876", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VUP0", "url": "https://www.uniprot.org/uniprotkb/Q9VUP0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VUP0-1", "url": "https://www.uniprot.org/uniprotkb/Q9VUP0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYTINKGPSKIVAKTRRGLAPNFEKFESIKESGRKNASFDLNSPEEHKNIPRPVFQQSFATKRITPTKLIEDEVITPQHEEIIRYINDSWNMLVAQNPYDSSSSAKPVEKPVADANNNSAASPVESIMANSPVPAASTATVWVEPPSPALQDFKPFDLESWWGRRLFQNITKSL", "length": 174, "header": "tr|Q9VUP0-1|Q9VUP0_DROME Isoform 1 of Protein FAM195A OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG7841 PE=3 SV=1 CANONICAL=Q9VUP0-1" }, "isoforms": [ { "isoform_ac": "Q9VUP0-1", "url": "https://www.uniprot.org/uniprotkb/Q9VUP0/entry#Q9VUP0-1", "sequence": { "sequence": "MYTINKGPSKIVAKTRRGLAPNFEKFESIKESGRKNASFDLNSPEEHKNIPRPVFQQSFATKRITPTKLIEDEVITPQHEEIIRYINDSWNMLVAQNPYDSSSSAKPVEKPVADANNNSAASPVESIMANSPVPAASTATVWVEPPSPALQDFKPFDLESWWGRRLFQNITKSL", "length": 174, "header": "tr|Q9VUP0-1|Q9VUP0_DROME Isoform 1 of Protein FAM195A OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG7841 PE=3 SV=1 CANONICAL=Q9VUP0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VUP0", "url": "https://www.uniprot.org/uniprotkb/Q9VUP0" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VUP0", "url": "https://www.uniprot.org/uniprotkb/Q9VUP0" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUP0", "url": "https://www.uniprot.org/uniprotkb/Q9VUP0" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUP0", "url": "https://www.uniprot.org/uniprotkb/Q9VUP0" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VUP0", "url": "https://www.uniprot.org/uniprotkb/Q9VUP0" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VUP0", "url": "https://www.uniprot.org/uniprotkb/Q9VUP0" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VUP0", "url": "https://www.uniprot.org/uniprotkb/Q9VUP0" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUP0", "url": "https://www.uniprot.org/uniprotkb/Q9VUP0" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUP0", "url": "https://www.uniprot.org/uniprotkb/Q9VUP0" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VUP0", "url": "https://www.uniprot.org/uniprotkb/Q9VUP0" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VUP0", "url": "https://www.uniprot.org/uniprotkb/Q9VUP0" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG7841", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG7841", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A8M7-1", "protein_name": "MAPK regulated co-repressor interacting protein 2", "gene_name": "Mcrip2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "PGPRVLLASVGSEKIWVPKIYRQPRFGCALWKPQQLRSLGSLRPRSGPEAQRTKPCATQQQVESRLGELLKCRQPVPPTALPTREQPSAQPQGPWPLASPGPRLVFNRVNGRRPLTTSPSLEGTQETYTVAHEENVRFVSEAWQQVERQLDGCPADDGGPRPVQYVESTPDPRLQNFVPIDLDEWWAQQFLAKITNCS", "length": 198 }, "evidence": [ { "id": "RGD:1592603", "url": "https://alliancegenome.org/gene/RGD:1592603#orthology", "database": "AGR" }, { "id": "HGNC:14142", "url": "https://alliancegenome.org/gene/HGNC:14142#orthology", "database": "AGR" }, { "id": "MGI:1915491", "url": "https://alliancegenome.org/gene/MGI:1915491#orthology", "database": "AGR" }, { "id": "FB:FBgn0036502", "url": "https://alliancegenome.org/gene/FB:FBgn0036502#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B0BN72-1", "protein_name": "Mapk-regulated corepressor-interacting protein 1", "gene_name": "Mcrip1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTSSPVSRVVYNGKRNSSPRSPTNSSEIFTPAHEENVRFIYEAWQGVERDLRSQLSSGERCLVEEYVEKVPNPSLKTFKPIDLSDLKRRNTQDAKKS", "length": 97 }, "evidence": [ { "id": "HGNC:28007", "url": "https://alliancegenome.org/gene/HGNC:28007#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060825-259", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060825-259#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "C9JLW8-1", "protein_name": "Mapk-regulated corepressor-interacting protein 1", "gene_name": "MCRIP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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corepressor interacting protein 2", "gene_name": "MCRIP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MYTITKGPSKLVAQRRTGPTQQQVEGRLGELLKCRQPAPPTSQPPRAQPFAQPPGPWPLSSPGPRLVFNRVNGRRAPSTSPSFEGTQETYTVAHEENVRFVSEAWQQVQQQLDGGPAGEGGPRPVQYVERTPNPRLQNFVPIDLDEWWAQQFLARITSCS", "length": 160 }, "evidence": [ { "id": "RGD:1592603", "url": "https://alliancegenome.org/gene/RGD:1592603#orthology", "database": "AGR" }, { "id": "HGNC:14142", "url": "https://alliancegenome.org/gene/HGNC:14142#orthology", "database": "AGR" }, { "id": "MGI:1915491", "url": "https://alliancegenome.org/gene/MGI:1915491#orthology", "database": "AGR" }, { "id": "FB:FBgn0036502", "url": "https://alliancegenome.org/gene/FB:FBgn0036502#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CQB2-1", "protein_name": "MAPK regulated corepressor interacting protein 2", "gene_name": "Mcrip2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MYTITKGPSKLVAQRRTGPTQQQVESRLGELLKCRQPVPPTALPAHLQPSAQTQGPWPLASSGPRLVFNRVNGRRPLTTSPSLEGTQETYTVAHEENVRFVSEAWQQVERQLDGGPADESGPRPVQYVESTPDPRLQNFVPIDLDEWWAQQFLAKITNCS", "length": 160 }, "evidence": [ { "id": "RGD:1592603", "url": "https://alliancegenome.org/gene/RGD:1592603#orthology", "database": "AGR" }, { "id": "HGNC:14142", "url": "https://alliancegenome.org/gene/HGNC:14142#orthology", "database": "AGR" }, { "id": "MGI:1915491", "url": "https://alliancegenome.org/gene/MGI:1915491#orthology", "database": "AGR" }, { "id": "FB:FBgn0036502", "url": "https://alliancegenome.org/gene/FB:FBgn0036502#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VUP0", "url": "https://www.uniprot.org/uniprotkb/Q9VUP0" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "Q9VUP0", "url": "https://www.uniprot.org/uniprotkb/Q9VUP0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 117, "end_pos": 119, "annotation": "n_glycosylation_sequon" }, { "start_pos": 169, "end_pos": 171, "annotation": "n_glycosylation_sequon" }, { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" }, { "start_pos": 87, "end_pos": 89, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 117, "end_pos": 119 }, { "start_pos": 169, "end_pos": 171 }, { "start_pos": 36, "end_pos": 38 }, { "start_pos": 87, "end_pos": 89 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VUQ9-1", "uniprot_ac": "Q9VUQ9", "uniprot_id": "Q9VUQ9_DROME", "mass": { "chemical_mass": 225509.0, "monoisotopic_mass": 225509.0 }, "refseq": { "ac": "NP_001261884", "name": "drop out, isoform B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261884" }, "gene_names": [ { "name": "dop", "type": "recommended", "evidence": [ { "id": "Q9VUQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUQ9" } ] }, { "name": "CG6498", "type": "synonym", "evidence": [ { "id": "NP_001261884", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261884" }, { "id": "Q9VUQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUQ9" } ] }, { "name": "Dmel\\CG6498", "type": "synonym", "evidence": [ { "id": "NP_001261884", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261884" }, { "id": "Q9VUQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUQ9" } ] }, { "name": "Dmel_CG6498", "type": "synonym", "evidence": [ { "id": "Q9VUQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUQ9" } ] }, { "name": "MAST 205", "type": "synonym", "evidence": [ { "id": "NP_001261884", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261884" }, { "id": "Q9VUQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUQ9" } ] }, { "name": "MAST205", "type": "synonym", "evidence": [ { "id": "NP_001261884", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261884" }, { "id": "Q9VUQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUQ9" } ] }, { "name": "dop", "type": "synonym", "evidence": [ { "id": "NP_001261884", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261884" } ] } ], "protein_names": [ { "name": "non-specific serine/threonine protein kinase", "type": "recommended", "evidence": [ { "id": "Q9VUQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUQ9/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "Q9VUQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUQ9/entry#names_and_taxonomy" } ] }, { "name": "CG6498-PB", "type": "synonym", "evidence": [ { "id": "NP_001261884", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261884" } ] }, { "name": "dop-PB", "type": "synonym", "evidence": [ { "id": "NP_001261884", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261884" } ] }, { "name": "drop out, isoform B", "type": "synonym", "evidence": [ { "id": "NP_001261884", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261884" } ] } ], "function": [], "disease": [ { "disease_id": "DOID:0050457", "recommended_name": { "id": "DOID:0050457", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050457", "name": "Sertoli cell-only syndrome", "description": "A male infertility disease characterized by male sterility, has_material_basis_in azospermia without abnormal sexual development." }, "synonyms": [ { "id": "DOID:0050457", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050457", "name": "DEL CASTILLO SYNDROME", "description": "" }, { "id": "DOID:0050457", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050457", "name": "Germinal Cell Aplasia", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "0050457", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050457" } ] }, { "disease_id": "DOID:0050671", "recommended_name": { "id": "DOID:0050671", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050671", "name": "female breast cancer", "description": "A breast cancer that develops from breast tissue in females." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "0050671", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050671" } ] }, { "disease_id": "DOID:0070394", "recommended_name": { "id": "DOID:0070394", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070394", "name": "developmental and epileptic encephalopathy 108", "description": "A developmental and epileptic encephalopathy characterized by onset of multiple types of seizures in the first 2 years of life that has_material_basis_in heterozygous mutation in the MAST3 gene on chromosome 19p13." }, "synonyms": [ { "id": "DOID:0070394", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070394", "name": "DEE108", "description": "" }, { "id": "DOID:0070394", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070394", "name": "early infantile epileptic encephalopathy 108", "description": "" }, { "id": "MONDO:0859314", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0859314", "name": "developmental and epileptic encephalopathy 108", "description": "" }, { "id": "MIM:620115", "resource": "MIM", "url": "https://www.omim.org/entry/620115", "name": "Developmental and epileptic encephalopathy 108", "description": "Developmental and epileptic encephalopathy 108" } ], "unlinked_id_list": [], "evidence": [ { "id": "0070394", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070394" } ] }, { "disease_id": "DOID:0111403", "recommended_name": { "id": "DOID:0111403", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111403", "name": "mega-corpus-callosum syndrome with cerebellar hypoplasia and cortical malformations", "description": "A syndromic intellectual disability characterized by global developmental delay, impaired intellectual development, and characteristic brain abnormalities that has_material_basis_in heterozygous mutation in the MAST1 gene on chromosome 19p13.13." }, "synonyms": [ { "id": "DOID:0111403", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111403", "name": "MCCCHCM", "description": "" }, { "id": "MONDO:0032648", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0032648", "name": "mega-corpus-callosum syndrome with cerebellar hypoplasia and cortical malformations", "description": "" }, { "id": "MONDO:0032648", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0032648", "name": "MCCCHCM", "description": "" }, { "id": "MIM:618273", "resource": "MIM", "url": "https://www.omim.org/entry/618273", "name": "Mega-corpus-callosum syndrome with cerebellar hypoplasia and cortical malformations", "description": "Mega-corpus-callosum syndrome with cerebellar hypoplasia and cortical malformations" } ], "unlinked_id_list": [], "evidence": [ { "id": "0111403", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111403" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VUQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VUQ9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "dop", "url": "https://www.uniprot.org/uniprotkb/Q9VUQ9", "locus": { "chromosome": "3L", "start_pos": 15576313, "end_pos": 15566013, "strand": "-", "evidence": [ { 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}, { "id": "Q9VUQ9", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VUQ9*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015022", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015022", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023142", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023142", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037711", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037711", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041489", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041489", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG6498", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG6498", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PHNIPPG", "url": "https://omabrowser.org/oma/group/PHNIPPG/", 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] }, { "id": "NP_001261884", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261884", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q9VUQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VUQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VUQ9-1", "url": "https://www.uniprot.org/uniprotkb/Q9VUQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRQEGAASRPADGATGPVASSSSSTSSNHSVSAVLGSKISTSTPQKNDEHQEQEFINQSVASEIEAMSISDSASAESSSGATATATATMSGSPVPKRHLSTANLSRIRPQSSYSARVLIFDDSDQEAAAAAAALAAASSSCNSSVKSCSGLELLPTSPAKLSIGNDSTNGSSMMRNLNLTKSSSGGLSGSSSSLHSRGYTALLRKISYQQHTNSLRAVSGETSNLLRMRHSSLGKSAPCLTGNYFRHELTAPLPVQPPGFGASPLGGHNISRSGSCAGIGLAKHHHHHHLHGVVMRGSAGGGAGSGGGSSSGVAHHRLSLVTNSAAVAAAGGSRTHSPYSASPVDSPRLNSPMPFAFAPIKRIASCRGVVADGRRWSVASLPSSGYGTTPGSSNLSSQCSSQEGLNQLAHNIPPGVQEADAAAVAAGACCAEHLKQHCPKHCALLLAVSQKQLTPQPPKPTQLQPQKSMTAACVNCCAELSVTCGGQQAGGGAANGGSSANSSGSSAMQVGGRMSPYFRPRSRSLSSPSRSPIVDNEIAVMNTLYKERFPKATQQMEERLKLFINENKSAACNSFRDSQPIVRFVHHQVLEMARDCLHKSEAKLITSQYFYELSENLERLLVETKEKSPEAAAELNGVIKKLLLIISRPARLLECLEFDPQEFYELLEAAEGHAKAMPVIKADIPQYIIHKLGLNRDPIAELQQELRETQQMCSEQVTVDADPLHPGGSLLLNSPLTSAAKQLSSLALDAIAMDSGSGTATPQQPPQTPVATCDTAPSFALAISQMNEEKGGSSSAVGGGSSSKVAGAEGITGGSAATATGSGAQQPSPQENDFDIVKLISNGAYGAVYLVKHKTTRQRFAMKKINKNNLILRNQVEQVFAERDILSFADNPFVVSMYCSFETKKHLCLVMEYVEGGDCGTLLKNIGPLPADMARFYFAETVLAVEYLHSYGIVHRDLKPDNLLITALGHIKLTDFGLSKMGLMSLATNLYEGYIDSETRQFSDKQVYGTPEYIAPEVILRQGYGKPVDWWSMGIILYEFLIGCVPFFGETTEELFAHTVNDDIEWPDSEDWPVQAEAKDIISQLLQQNPRDRLGTQSGALEMKEHEYFLGMDWNSLLRQKAEFVPQLSHDDDTSYFDTRMDRYNHDLGGEDTDDTDDTPVFGSFNSYTPQYRKQHYSWSRHATPTSTDGAKPTGPPPLSSLPSRAQETPAATVGATSTGALPKLKSGMGSGSGSGSGSGSGSASHDGVVNKFLNTPQLRKLDLSSSCLKVPSTPDADYLPELLHNVTIGNDAELRMLKHYLQQPNPGATQRMQQRHSMPPNTTTIISTPATPPPTQTQATMAATPPTATVGSFSRSTPESSQTDSDDFSPQINRKRKGVCARDILPRFSISIEDETISAGSSSTENMNLPREQSPLALQHQPKSMDGSTSGSSVKHHRSRSIVKSASALGLSLMTSLDNSQLAAQLCGIQSPGGGGNGSSTASSRDTSPCRELSPLVTNLKPPIIIRRGPRGFGFTVHTIRVYYGDTDFYTMHHLVMAVDEGSPAFEAGLRPADLITHVNGEAVQGLFHTQVLQLLLSGGEHVTLRATPLEHTSIQSGGRKRDLMQSKLAKKGVNRQKKQTKREHDKKRKTSLFRRISSKRANAEMQQYSAGTSSPTTPSARNLSPLDSSYHSSCCQSAANSSSQSTSPSSSSPNTPTGSSGSNHGGNAGSVAVAPSALSVQLPSAPPPTQLVLLPHVGAVVGSNPTSVGNVPVSPTGVVPQLYQRPSTLHGLKHKLHAATAVIAGGGNANNPAGGLKTLHTTNNNSLPNRRKSVGHIPLSPLARTPSPSPLPSSPTRSPSPLAFPLVGHQPGASNTTQSYSPGSTLPTLQTAVNANTKKAGFARTKSAEPSSPLLRRALSPDRLHPRSAETKISPLCCSPPIKQPTHQRVVTTTWRSTPGGSASGAGGAVLGAPSVQPLQLVPAASEESQRQTAMATVVSTTAAGTDPSATAVVTLANCEPLPRIAEEKDSPTSTQDSSSVSEGFMPAIEEFAEGESSSSPTQTLEKPTKVKATEQPEMEPAGKSKKVDQGKTTTPGTPKTKPHNSGCKTSMTTTKPASPSVTISTAPRKDTSAVTGGGSSGSGGSAATSAAKQRK", "length": 2139, "header": "tr|Q9VUQ9-1|Q9VUQ9_DROME Isoform 1 of non-specific serine/threonine protein kinase OS=Drosophila melanogaster OX=7227 GN=dop PE=1 SV=1 CANONICAL=Q9VUQ9-1" }, "isoforms": [ { "isoform_ac": "Q9VUQ9-1", "url": "https://www.uniprot.org/uniprotkb/Q9VUQ9/entry#Q9VUQ9-1", "sequence": { "sequence": "MSRQEGAASRPADGATGPVASSSSSTSSNHSVSAVLGSKISTSTPQKNDEHQEQEFINQSVASEIEAMSISDSASAESSSGATATATATMSGSPVPKRHLSTANLSRIRPQSSYSARVLIFDDSDQEAAAAAAALAAASSSCNSSVKSCSGLELLPTSPAKLSIGNDSTNGSSMMRNLNLTKSSSGGLSGSSSSLHSRGYTALLRKISYQQHTNSLRAVSGETSNLLRMRHSSLGKSAPCLTGNYFRHELTAPLPVQPPGFGASPLGGHNISRSGSCAGIGLAKHHHHHHLHGVVMRGSAGGGAGSGGGSSSGVAHHRLSLVTNSAAVAAAGGSRTHSPYSASPVDSPRLNSPMPFAFAPIKRIASCRGVVADGRRWSVASLPSSGYGTTPGSSNLSSQCSSQEGLNQLAHNIPPGVQEADAAAVAAGACCAEHLKQHCPKHCALLLAVSQKQLTPQPPKPTQLQPQKSMTAACVNCCAELSVTCGGQQAGGGAANGGSSANSSGSSAMQVGGRMSPYFRPRSRSLSSPSRSPIVDNEIAVMNTLYKERFPKATQQMEERLKLFINENKSAACNSFRDSQPIVRFVHHQVLEMARDCLHKSEAKLITSQYFYELSENLERLLVETKEKSPEAAAELNGVIKKLLLIISRPARLLECLEFDPQEFYELLEAAEGHAKAMPVIKADIPQYIIHKLGLNRDPIAELQQELRETQQMCSEQVTVDADPLHPGGSLLLNSPLTSAAKQLSSLALDAIAMDSGSGTATPQQPPQTPVATCDTAPSFALAISQMNEEKGGSSSAVGGGSSSKVAGAEGITGGSAATATGSGAQQPSPQENDFDIVKLISNGAYGAVYLVKHKTTRQRFAMKKINKNNLILRNQVEQVFAERDILSFADNPFVVSMYCSFETKKHLCLVMEYVEGGDCGTLLKNIGPLPADMARFYFAETVLAVEYLHSYGIVHRDLKPDNLLITALGHIKLTDFGLSKMGLMSLATNLYEGYIDSETRQFSDKQVYGTPEYIAPEVILRQGYGKPVDWWSMGIILYEFLIGCVPFFGETTEELFAHTVNDDIEWPDSEDWPVQAEAKDIISQLLQQNPRDRLGTQSGALEMKEHEYFLGMDWNSLLRQKAEFVPQLSHDDDTSYFDTRMDRYNHDLGGEDTDDTDDTPVFGSFNSYTPQYRKQHYSWSRHATPTSTDGAKPTGPPPLSSLPSRAQETPAATVGATSTGALPKLKSGMGSGSGSGSGSGSGSASHDGVVNKFLNTPQLRKLDLSSSCLKVPSTPDADYLPELLHNVTIGNDAELRMLKHYLQQPNPGATQRMQQRHSMPPNTTTIISTPATPPPTQTQATMAATPPTATVGSFSRSTPESSQTDSDDFSPQINRKRKGVCARDILPRFSISIEDETISAGSSSTENMNLPREQSPLALQHQPKSMDGSTSGSSVKHHRSRSIVKSASALGLSLMTSLDNSQLAAQLCGIQSPGGGGNGSSTASSRDTSPCRELSPLVTNLKPPIIIRRGPRGFGFTVHTIRVYYGDTDFYTMHHLVMAVDEGSPAFEAGLRPADLITHVNGEAVQGLFHTQVLQLLLSGGEHVTLRATPLEHTSIQSGGRKRDLMQSKLAKKGVNRQKKQTKREHDKKRKTSLFRRISSKRANAEMQQYSAGTSSPTTPSARNLSPLDSSYHSSCCQSAANSSSQSTSPSSSSPNTPTGSSGSNHGGNAGSVAVAPSALSVQLPSAPPPTQLVLLPHVGAVVGSNPTSVGNVPVSPTGVVPQLYQRPSTLHGLKHKLHAATAVIAGGGNANNPAGGLKTLHTTNNNSLPNRRKSVGHIPLSPLARTPSPSPLPSSPTRSPSPLAFPLVGHQPGASNTTQSYSPGSTLPTLQTAVNANTKKAGFARTKSAEPSSPLLRRALSPDRLHPRSAETKISPLCCSPPIKQPTHQRVVTTTWRSTPGGSASGAGGAVLGAPSVQPLQLVPAASEESQRQTAMATVVSTTAAGTDPSATAVVTLANCEPLPRIAEEKDSPTSTQDSSSVSEGFMPAIEEFAEGESSSSPTQTLEKPTKVKATEQPEMEPAGKSKKVDQGKTTTPGTPKTKPHNSGCKTSMTTTKPASPSVTISTAPRKDTSAVTGGGSSGSGGSAATSAAKQRK", "length": 2139, "header": "tr|Q9VUQ9-1|Q9VUQ9_DROME Isoform 1 of non-specific serine/threonine protein kinase OS=Drosophila melanogaster OX=7227 GN=dop PE=1 SV=1 CANONICAL=Q9VUQ9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1333, "start_aa": "Thr", "end_pos": 1333, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1333", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1660, "start_aa": "Thr", "end_pos": 1660, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1660", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VUQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VUQ9" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VUQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VUQ9" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VUQ9" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VUQ9" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VUQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VUQ9" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VUQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VUQ9" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VUQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VUQ9" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VUQ9" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VUQ9" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VUQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VUQ9" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VUQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VUQ9" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG6498", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG6498", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZMP0-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Mast2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKRSRCRERPQPPPARREDAAPRAAELPQPQSLPPRRRAPPGRQLLEERSGPMGHDSREQDMVSGLSPLLFRKLSNPDIFSPTGKAKLQRQLSQDDCKLRRGSLASSLSGKQLLPLSSSVHSSVGQVTWQSTGEASNLVRMRNQSLGQSAPSLTAGLKELSLPRRGSLISTLCRGADLTQHMFSPSSAPALSLARVPLSADCVLSTSPLVFFLNPQAHSSPCSPCSSRTLQWSCRTSNRKSLIVTSSTSPTLPRPHSPLHGHTGNSPLDSPRNFSPNAPAHFSFVPARRTDGRRWSLASLPSSGYGTNTPSSTVSSSCSSQEKLHQLPFQPTADELHFLTKHFSTENVPDEEGRQSPAMRPRSRSLSPGRSPVSFDSEIIMMNHVYKERFPKATAQMEERLAEFISCNTPDSVLPLADGALSFIHHQVIEMARDCLDKSRSGLITSHYFYELQENLEKLLQDAHERSESSDVAFVIQLVKKLMIIIARPARLLECLEFDPEEFYHLLEAAEGHAKEGHGIKCDIPRYIVSQLGLTRDPLEEMVQLSSYDSPDTPETDDSVEGRGASQPSKKTPSEEDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVSMFCSFETKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKIGLMSLTTNLYEGHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEIVWPEGDDALPPDAQDLTSKLLHQNPLERLGTSSAYEVKQHPFFMGLDWTGLLRQKAEFIPQLESEDDTSYFDTRSERYHHVDSEDEEEVSEDGCLEIRQFSSCSPRFSKVYSSMERLSLLEGHRTPPPTKRSLSEEKEDHSDGLAGLKGRDRSWVIGSPEILRKRLSVSESSHTESDSSPPMTVRHRSGLPDVPRCAEETSSTPRKQQQEGIWVLTPPSGEGSSRPVPERPLERQLKLDEEPPGQSSRSCPAMETRGRGTPQLAEEATAKAISDLAVRRARHRLLSGDSIEKRTTRPVNKVIKSASATALSLLIPSEHHACSPLASPMSPHSQSSNPSSRDSSPSRDFLPALGSLRPPIIIHRAGKKYGFTLRAIRVYMGDSDVYTVHHMVWHVEDGGPASEAGLRQGDLITHVNGEPVHGLVHTEVVELVLKSGNKVSISTTPLENTSIKVGPARKGSSKAKMARRSKRSRGKDGQESRKRNSLFRKITKQASLLHTSRSLSSLNRSLSSGESGPCSPTHSHSLSPRSPPQGYRVAPDTVHSGGNSSQSSSPSSSVPSSPAGSGHTRPSSLHGLAPKLQRQYRSPRRKSAGSIPLSPLAHTPSPPAAAASPQRSPSPLSGHGSQSFPTKLHLSPPLGRQLSRPKSAEPPRSPLLKRVQSAEKLAAALAAAEKKLAPSRKHSLDLPHGELKKELTPREANPLEVVGTRSVLSGKGPLPGKGVLQPAPSRALGTLRQDRAERRESLQKQEAIREVDSSEDDTDEEPENSQATQEPRLSPHPEASQNLLPKGSGEGREEDTFLHRDLKNRGPVLSGLLTGNRIEVPGLSQRKLWRPQAFEEATNSLQAPSLSRSGPTSPTPSEGCWEARQLHTQALATLHPSSSELTPTSCSAATSTSGKPGTWSWKFLIEGPDRASTNKKITRTGEPANSQDLETTVPTQVPKNLSPEEEKPQPPSVRGLTHPLLEVPSQNWLWESGCEQMEKEDPSLSITEVPGSSGNRRQDIPCRAHHLSPETRPSLLWRSQELGGQQEHQDLALTSDELLKQT", "length": 1853 }, "evidence": [ { "id": "HGNC:19035", "url": "https://alliancegenome.org/gene/HGNC:19035#orthology", "database": "AGR" }, { "id": "MGI:894676", "url": "https://alliancegenome.org/gene/MGI:894676#orthology", "database": "AGR" }, { "id": "RGD:1304573", "url": "https://alliancegenome.org/gene/RGD:1304573#orthology", "database": "AGR" }, { "id": "FB:FBgn0267390", "url": "https://alliancegenome.org/gene/FB:FBgn0267390#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A5R8-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Mast3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDEPSLLRRRGLQKELSLPRRGRGLSPSSQSPCLLSPGSPCSPCSPSLGLQQPWSCRSGNRKSLVVGTPSPTLSRPLSPLSVPTAGNSPLDSPRNFSAAAAINFPFARRADGRRWSLASLPSSGYGTNTPSSTVSSSSSSRERLHQLPFQPTADELRFLSKHFRSSESVVDEDGGRSPRLRPRSRSLSPGRTSGTFDNEIVMMNHVYRERFPKATAQMEGRLQDFLAAFAPGDRLALADGVLGFIHHQIVELARDCLAKSGEALVTSRYFLEMQDKLERLLQDAHERSDSAEVGFIVQLVRKLLIIISRPARLLECLEFDPEEFYHLLEAAEGQAREDQGVKTDLPRYIIRQLGLAKDPLEEIQPLNDLDEGQPPAPGSPESRGLGGPSRRQPCESDFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVFVERDILTFAENPFVVGMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARMYFAETVLALEYLHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLYEGHIEKDAREFVDKQVCGTPEYIAPEVIFRQGYGKPVDWWAMGVILYEFLVGCVPFFGDTPEELFGQVVSDEIMWPEGDEALPPDAQDLITRLLRQSPMDRLGTGGTHEVKQHPFFLALDWAGLLRHKAEFVPQLEAEDDTSYFDTRSERYRHLGSEGDETNDEESSTEIPQFSSCSHRFSKVYSSSEFLAVQPNPTFAERSFSEDREEGWEQSGEGDGGRRLSTDLRLRSWTPASSCQPSSCQSDRGPSPSLLSTISLDMPKFAFSSEDEGAGSGPADTRKPVFILGEPDPPPPTTPVTPKPCNLSADTAVLSHARLRSNSTGARHSTPRPLDAGRGRRLGSSRDPGPEKPRASPGGSGGRVPKSASVSALSLIITADDGSGGPLMSPLSPRSLSSNPSSRDSSPSRDPSPVCGSLRPPIVIHSSGKKYGFSLRAIRVYMGDSDVYTVHHVVWSVEEGSPAQEAGLRAGDLITHINGESVLGLVHMDVVELLLKSGNKISLRTTALENTSIKVGPARKNVAKGRMARRSKRSRRRETQDRRKSLFKRISKPSSVLHTSRSFSSGLQHSLSSSESLPGSPTHSLSPSPTTPCRSPAPDVPTDTASPPSVSPSSSSPASPATGHTRPSSLHGLAAKLGPPRHKSGRRKSTSSIPPSPLACPPVPTPPPRSPSPLPGHIPIPARSPRLRRGQSADKLGLGTSERLDGDGGRRGRGAETELVVMRRLHLSERRDSFKKQEAVQEVSFDEEPGPTGAVPKIAVQGAEATPGSPGPARED", "length": 1330 }, "evidence": [ { "id": "HGNC:19036", "url": "https://alliancegenome.org/gene/HGNC:19036#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040914-35", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040914-35#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-111209-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-111209-1#orthology", "database": "AGR" }, { "id": "MGI:2683541", "url": "https://alliancegenome.org/gene/MGI:2683541#orthology", "database": "AGR" }, { "id": "RGD:1587639", "url": "https://alliancegenome.org/gene/RGD:1587639#orthology", "database": "AGR" }, { "id": "FB:FBgn0267390", "url": "https://alliancegenome.org/gene/FB:FBgn0267390#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M3AKH8-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "mast1a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDSMDDSGIIRRRRMQKDLPLPRKSSGCRTSNRKSLILTSTSPTLPRPHSPLPGHIGSSPLDSPRTFSPSAPAHFSFASSRRADGRRWSLASLPSSGYGTNTPSSTSSSSSQERLHQLPFQPTLDELHFLTKHFGSTESITDDDGRRSPHMRPRSRSLSPGRSSSCYDNEIVMMNHVYKERFPKATAQMEERLADFIESYSPENVLPLADGVLSFIHHQIAELSRNCLTKSREGLITTVYFYELQENLEKLLHEAYERSESSELTFITELVKKLFIIISRPARLLECLEFNPEEFYHLLEAAEDHAKEGQLMKADIPRYIISQLGLTRDPLEDMVNLESYDSEGPHTPETDDSAEGKLKAIKPPCESDFQTIKLISNGAYGAVYLVRHRETRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNIGALPVDMARMYFAETVLALEYIHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKMGLMNLTTNLYEGHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVITDYIEWPNGDEALPADAQSLISSLLQTNPLVRLGTGGAFEVKQHSFFSGLDWNGLLRQKAEFIPHLESEEDTSYFDTRSERYRHINSYDEDDTNDDEPVEIRQFSSCSPRFSKVYSSMEHLSQLEQKTPVVTRREHKGRRDDKITKRESFGSFSMRDKSWRTGSPEMKRLSCSESLYMEGDCSPPMGARRRFSALMDTHRFASSQEGDGERQVTAKATGSSEGAVPPSSPSANEQRNGKEVMSISSSKSTDKASRPGEVSAPQTIPSTGAPAVISRDLVAIGDPVGQRATKDLVLRRARHQQLSSDGEKRTSRPGNKVIKSASATALSVIIPGVEQHGNSPLASPMSPRSLSSNPSSRDSSPSRDYCPTVTVPRSPITIQRSGKKYGFTLRAIRVYIGDTDVYSVHHIVWHVEDGGPAQEAGLCAGDLITHVNGESVHGLVHTEVVELILKSGNKVTVTTTPFENTSIKVGPARRSSYKSKMARRSKRTVKEGQESKRRGSLFRKITKQSNLLHTSRSLSSLNRSLSSSDSLPGSPTHSLSGHSPTQSYRSTPESSHLGASSQSSSPASSTPNSPATTQHMRPSSLHGLSPKLHRQYRSARCKSAGNIPLSPLAHTPSPTQSSPPPLPGHTVGSSNTTQTFPAKLHSSPPIIRPRPKSAEPPRSPLLKRVQSAEKLGSPLSSSSEKKGGIGVMRKHSLEVGHSDYRKDGFHCELGLQSLVEIEGENLASAPTNSPSPTQPTPLPPETGVLKPVRKLGRQESPLSRDALLAGRERERERERERERTGKANEPSRPTESKPAAVTPPGSKTSPNSETSQRHTSTIQECCLVKPQTWQPPLTKSSPIASESKSNIVTSIPSPLTTVSSPSTKTIDQSSIREEGNDDKGSLTKIPQSQTLGTTKSPLSLIPSELINKDLLEKGGNDNGKKQVKSDVGNTSAQGKPSIPCSPPVKTTSTEVTKANEGFGNGDSLKKGVLDPHSRTSDVRVRTALAPSKGLVPSHPPQTQCSALGKLRQDKGLSAVSCYRGSFDWEDKCLLEVVEEHSPSPTPSPTGVPPDLLKSQPPAERTGLVTHLTSTGKSIGAVKGGTQEGPKAKDTNKSLEITQACAPGRPESSPEGRPNSKGASPTSSSPQVKTLITPKNGS", "length": 1738 }, "evidence": [ { "id": "HGNC:19034", "url": "https://alliancegenome.org/gene/HGNC:19034#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121214-221", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121214-221#orthology", "database": "AGR" }, { "id": "MGI:1861901", "url": "https://alliancegenome.org/gene/MGI:1861901#orthology", "database": "AGR" }, { "id": "RGD:631372", "url": "https://alliancegenome.org/gene/RGD:631372#orthology", "database": "AGR" }, { "id": "FB:FBgn0267390", "url": "https://alliancegenome.org/gene/FB:FBgn0267390#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3AXH0-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "mast3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKRRDKLKIPSLTLDLSPSQSPIILSPCSPGSPCSPLQSLHPWSCRSSNRKSLGVGTPSPTRPLSPLSAHTAASSPLDSPRNVSTAICSLNFPFARSHLARADRAEGRRWSLASLPSSGYGTNPPSSTVSSSSSSQERLHQLPYQPTQDELHFLFKHFRSSESMTDEDGRPSTFIRPRSRSLSPGRTGGSFDNEIIMMNHVYKERFPKATAQMEERLLDIIRHFSPDSTLPLGDGVLGFIQHQLVELARDCLDKSQKGLITSLYFIELQDKLEKMLHEALDRSESEEVSIITQLIKKILIIISRPARLLECLEFDPEEFYHLLEAAEGHAKVGQGIKTDIPRYIISQLGLNWDPLDEVVQLEEQFDSGPTLTVDSQESAEQNKVSTPLRRKPLESDFETLKLISNGAYGAVHLVRHKETRQRFAMKKINRQNLILRNQIQQVFVERDILTFAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMTRMYFAETVLALEYLHSYGIVHRDLKPDNLLITSMGHIKLTDFGLSKIGLMNMTTNLYEGHIEKDTREFIDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVVSDEIIWPDGDDALPVDAQDMITRLLNQSPLERLGTGGAPEVKQHMFFSGLDWNGLLRQKAEFIPQLEGEDDTSYFDTRSERYHHLASDEDEETNDEESSLEIRRFSSWSNRFSKVYSSTEHLATPSNLSFSSDRSHSEEIEDRADTHYHGEIQRQASTGDKRLSAQRASLRPRTSSSSSQPERAVSPLVVSSTHSLEAMPRFALSTDDEAEVVVSNLRRIRLRSNSTGTKHSSPREQGGPPCFGNQLETPDKQRLSPGRKVPKSASVSTLSLIITPDDGSGSLQGRSISPRSFSSNPSSRDSSPNRDLSLSISRLRPPIIIHSSGKKFGFTLQTIRVYMGNSDIYTIHHMVSGVEESSPAHEAGLRAGDLITHVNGESVQGLVHTEMMELLLKSGNQVTLQTIALEDTSIKIGPARKSRCKGKMARRCKSRWKDNKDRRRNMLKKLSKQSTVMHSSRSFSSGLHHSVSSSESLPGSPTHSLSSGPTTPCRSPVPDHTTDTGLPQNASPCSSSPSSPAVQMRPSSLHGLGSKLGNQRYTKVGRRKSTSSIPPSPLACTSSPQALSPQRSPSPLPSISKTLHSFHGKTLSPPTIIRHVVRPRSAEPPRSPLLKRVQSAEKLSGALFADKKPHAARRHTLEVPHCELDVSGDAEGEVACGSVYTTDHGRLGGYLCAQRLRDWPSERMEQIVVMRKLNLSERRDSFKKQEAVQEVSFDEPDAPQTSAQTGTSTGTRPKHIMGESQSEEECVARRNPLVPQIAVQGSESEEADDWRLCSDEDEDEAEENVLLTRNQGEPRIHTANISSVATCEATGVITVTAMPENHPNPEKSKLINR", "length": 1456 }, "evidence": [ { "id": "HGNC:19036", "url": "https://alliancegenome.org/gene/HGNC:19036#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-111209-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-111209-1#orthology", "database": "AGR" }, { "id": "MGI:2683541", "url": "https://alliancegenome.org/gene/MGI:2683541#orthology", "database": "AGR" }, { "id": "RGD:1587639", "url": "https://alliancegenome.org/gene/RGD:1587639#orthology", "database": "AGR" }, { "id": "FB:FBgn0267390", "url": "https://alliancegenome.org/gene/FB:FBgn0267390#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3AXQ6-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "mast1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDDSGIIRRRRLQDLPLPRKNSSCRSNRKSLILTSTSPTLPRPHSPLPGHIGSSPLDSPRNFSPSTPAHFSFASSRRDGRRWSLASLPSSGYGTNTPSSTSSSSSQERLHQLPSQPTMDELHFLSKHFGSTESITDDDGGRCSPHIRPRSRSLSPGRSHSCYDNEIIMMNHVYRERFPKATAQMEGRLCDFVHSYCPENVLPLADGVLSFIHHQIIELSRDCLTKSREGLITSVYFFELQENLEKLLDDAYKRSESSELTFVTELVKKIFFIIARPARLLECLEFNPEEFYHLLEAAEDHAKEGHLMKTDIPRYIISQLGLTRDPLEEMVSREHYDSEGPVTPETDDSAEGKMKPMKPPGEADFQTIKLISNGAYGEVYLVRHLETRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNIGALPVEMARMYFAETVLALEYIHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKMGLMSLTTNLYEGHIEKDTREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDDIVWPEDDDALPPDAQHLISSLLQTSPLLRLGTGGAFEVKQHPFFGDLDWGSLLRQKAEFIPNLESEEDTSYFDTRSERYHHVHSYDEDDTNDDEPVEIHRFSSCSPRFSKVYSSMEHLSQLEHKPVVTRREPKPHREDRAKRESMGSLTLRDKTWRTGSPEMKRLSCSESSFTESDSSPPGARRRFSALMDTHRFASPLEGDSDTHTRQPPVKTRGTSLEGASVPVSSGLFESSSAVSVGHPGDKLLRPAEGPSAPLHMPEPFSARVGSDLVLRRARHHQIPSDSEKRTATRSGTKVIKSASATALSVIIPAVEQHGTSPLASPMSPRSVSSNPSSRDSSPSRDYSPTVNVLRSPITIHRSGKKYGFTLRAIRVYMGDSHVYSVHHMVWHVECGGPAQEAGLCAGDLITHVNGEPVHGLVHTEVVELILKSGSKVTVTTTPFENTSIKIGPARKLSYKAKMARRNKKSAAKDGQESKKRSSLFRKITKQSNLLHTSRSLSSLNRSLSSGDSLPGSPTHNLSARSPTQTYRSPPDSTYLGTSSQSSSPASSTPNSPATSQHMRPSSLYGLSPKLHRQYRSARCKSAGNIPLSPLAHTPSPTSSSPPPIAGHIVGSSNTTQAFPAKLHASPPITRPRPKSAEPPRSPLLQRVQSAEKLGPPSPPSSSSSDRKGGLGIRKHGLDVVHAEYRRESFHCEHALQSLMEIEGENTPSALPSPPDQTPTHMPIKHTLSPARQLGRQDSIMDREFEGKSKQADSSEAILKTASKTEPVAIIVDLKSTPLGETTQRDKVASKFESSQVSVASMGKVVAKDVGKIESSSTLVTGPKIPDWTPIVQSSGVQELKPHQTESPKGLENGKDIGKIPVKEKTQLTKTPEASKSSKGPLNVEGTGSGSIGTPKVSEAVPSQSKSIQERAQTPSGSTRGPQEERCRLEAVEVSPPSPSPIARSPCTSKSRAISPGDRSSFVTQLTSVAKTVLGPMKLGSQDGGKAKDSSKTNEDKRAATLGKSEASSGGRRGLTGTWPGPGSSSKPEKASKSSSKHS", "length": 1634 }, "evidence": [ { "id": "HGNC:19034", "url": "https://alliancegenome.org/gene/HGNC:19034#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131025-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131025-2#orthology", "database": "AGR" }, { "id": "MGI:1861901", "url": "https://alliancegenome.org/gene/MGI:1861901#orthology", "database": "AGR" }, { "id": "RGD:631372", "url": "https://alliancegenome.org/gene/RGD:631372#orthology", "database": "AGR" }, { "id": "FB:FBgn0267390", "url": "https://alliancegenome.org/gene/FB:FBgn0267390#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PPY9-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "mast3a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDRNYWTVCPSYKSQFVSGGLVKRPKSNRNKRKSLAPSPTLSRPLSPLHLPTGSSPLDSPRNVSGSPSVNFPFIRRPDTRRWSVASVSSGYGTNPPSSAVSSSSSSQELLHQLPSQPTPDDLNRLFKHFRSTESVADEDGQPSRFHPRSRSLSPGRTCGSFDNEIVMMNHVYKERFPKATAQMEGRLLAVIADYSPDSAPPLADGVLGFIQHQLVELVRDCLEKSRKGLITSSYFMELQEKLENFLHEAYERSESEEVTVIAKLVKKILIIISRPARLLECLEFDPEEFYQRLEVAEGQAKVGQGIKTDIPRYIISQLGLTRDPLEDMVQLEHNSSGSSSRELDDSAENRPGIMTPRRKPLERDFETIKLISNGAYGAVYLVRHRETRQRFAMKKINRQNLILRNQIQQVFVERDILTFAENPFVVSMYCSFETRRHLCMVMEYVEGGDCANLLKNMGPLPVDMARMYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKIGLMNMTTNLYEEHMEKDTREFIDKQLCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVVSDEIEWPVGDDALPAESQDLITKLLRQSPLERLGTGGAAEVKHHIFFHGLDWSGLLRQKAEFIPQLETEDDTSYFDTRSDRYHHSDEDDETNDDESYQDIKFSSCSHRFSKVYSSSEQLASPSNLSLSSSERSCSEEKEDRWDTHSALSPVETPRQIQPADRKQDTSRGSPSLRPRASSSSSQPERGTSPLILNSTQSLEAMPHFAFPEDEEGLVSNLRRIRLRSNSTGTRPTNRRDHKGPRRLGLQQETPEKPRSPFTCKVPKSASVSGLSLIVTADDIPSGLQTSPMSSHSLSSNPSSRDSSPNRDISLSTSSLRPPVVIHSSGRKYGFALRAIRVYMGDSDVYTVHHMVWSVEDCSPAHEAGLRAGDLITHVNGECIQGLVHTDVVELLLKSGSKVTLQTTPLENTSIKIGPARKTSSKGKMARRSKKSKRKEGQDSKRRNLLKKLPKHSPGIQNSRSFSAGFQHSPNDSLSDSPTPSLSPGPNTPCRSPAPDLSCDSNSPQSSSPCSSSPNSPIPQSRPSSLHVLGSKIGLRYSKAGRCKSSNSIPPSPLACNPSSQPLSPQCSPSSLTGPPKGHHSFHNKMMSPPTIVRQTVCPRSAESPRSPLLNRVQSSERLSSAQYGDKRSFSSPRHTVEFPQSEADEFESQSPDIASGFVCVGDHARQGLYMSGQRVRESSGLVMRKLNLCERRDSFKKQEAVQEVSFDDSDDKELTTSTPTHSRFKVSWVSETQDEGDSETSGRKTDEVGSKRQEQKKHKDEC", "length": 1355 }, "evidence": [ { "id": "HGNC:19036", "url": "https://alliancegenome.org/gene/HGNC:19036#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040914-35", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040914-35#orthology", "database": "AGR" }, { "id": "MGI:2683541", "url": "https://alliancegenome.org/gene/MGI:2683541#orthology", "database": "AGR" }, { "id": "RGD:1587639", "url": "https://alliancegenome.org/gene/RGD:1587639#orthology", "database": "AGR" }, { "id": "FB:FBgn0267390", "url": "https://alliancegenome.org/gene/FB:FBgn0267390#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABK0M1X8-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Mast4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEKVSEAPEPVPRGCSGLGTRTLGSPAAAVSSEGASSAESSSGSETLSEEGEPGRFSCRSQPPRPPGGALGSRLPAAWAPARVVLERGVPTLPLPPPGGAVLPVPRVSSASQEEQDEELDHILSPPPMPFRKCSNPDVACGLGKSLKYKRQLSEDGKQLRRGSLGGALTGRYLLPNPVAGQAWPASAETSNLVRMRSQALGQSAPSLTASLEGQPPKSHFNSARHRQRLVDPAASKKELSLPRRGSLVDSQKWNCLVKRCRTTNRKSLISNGQSPALPRPHSPLSAHAGNSPQDSPRNFSPSASAHFSFARRTDGRRWSLASLPSSGYGTNTPSSTVSSSCSSQEKLHQLPYQPTPDELHFLSKHFCTTESIATENRCRNTPMRPRSRSLSPGRSPACCDHEIIMMNHVYKERFPKATAQMEDRLKEIVTSYSPDNVLPLADGVLSFTHHQIIELARDCLDKSHQGLITSRYFLELQHKLDKLLQEAHDRSESGELAFIKQLVRKILIVIARPARLLECLEFDPEEFYYLLEAAEGHAKEGQGIKSDIPRYIISQLGLNKDPLEEMAQLGNYDSRTAETPETDESVSSSNTSLRLRRKPRESDFETIKLISNGAYGAVYFVRHKESRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVSMYCSFETRRHLCMVMEYVEGGDCATLMKNMGPLPVDMARMYFAETVLALEYLHNYGIVHRDLKPDNLLVTSMGHIKLTDFGLSKVGLMSMTTNLYEGHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEINWPEKDEAPPPDAQDLITLLLRQNPLERLGTGGAYEVKQHRFFRSLDWNSLLRQKAEFIPQLESEDDTSYFDTRSEKYHHMETEEEDDTNDEDFTVEIRQFSSCSHRFSKVFSSIDRITQNSGEDKDDSEDKTKSTTLPSTETLSWSSEYSEMQQLSTSNSSDTESNRCKLSSGLLPKLAISAEGEHGEAVPCSGDPREEPDKPVLPPEEGTQEEPEVTTPASTISSSTLSVGSFSEHLDQINGRSECVDSTDNSSKPSSESASHMARQRLESTEKKKMSGKVTKSLSASALSLMIPGDMFAVSPLGSPMSPHSLSSDPSSSRDSSPSRDSSAASASPHQPIVIHSSGKNYGFTIRAIRVYVGDSDIYTVHHIVWNVEEGSPACQAGLKAGDLITHINGEPVHGLVHTEVIELLLKSGNKVSITTTPFENTSIKTGPARRNSYKGRMVRRSKKSKKKESLERRRSLFKKLAKQPSPLLHTSRSFSCLNRSLSSGESLPGSPTHSLSPRSPTPSYRSTPDFPSGTNSSQSSSPSSSAPNSPAGSGHIRPSTLHGLAPKLSGQRYRSGRRKSAGSIPLSPLARTPSPTPQPTSPQRSPSPLLGHSLGSAKITQAFPSKMHSPPTIVRHIVRPKSAEPPRSPLLKRVQSEEKLSPSYGSDKKHLCSRKHSLEVTQEEVQREQCQREVMLQSLEENVYDAPSLSRARPVEQGCLKRPVSRKMGRQESADDLDRDKLKAKVVVKKPEEKHEPHQKPHSLGSDSESYALFRLEEREKKVYPKGLERSGHFENTSAESPSVGSLLKDTLHKQASVRASEGVTLDGAACSLAPGEHSQSLGDFKRASASGNLHDSVCPISDRPAPGKVEYSEKASQAKELLRSEKLDSKLANIDYLRKKMSLDDKDDSHCAILKPKITSSTHECLLGNPVRPMAGQQETLSASENRAFINSTHTPQMSGVSFVPLKALAGRVENGGEKPGLAVPESPVRKSPSEYKLEGRSVSCLKPIEGTLDIALLSGPHASKTEPSPEPAQSPSPGINVGPSVPPALPGSSGKKGDSASLREPSSANLKVNKSYLQEPRFLPPSRALQDSLAAPGPDRKSKQERTIIHPSARSTATVTESNRQQKESGPATHQDRSTDTKVLPGPGQTLHNADPPRLCTRAPLPPEAASKEKPCLKEPSAKVKSEWSAIRNDGHRDPCVKLCPAEAGKVSDSSKPLPSGGRTHPDFYKQTQTSEKAWACAKTNHKDSQDEVKSLAREDSLHSASLLYEKEVGQARKGPEPKPEVPATRCPSQPPGIEGEKSEKLSAAPSLQKQAPKEPDRKEQALQRSGGGGPQQPPSTKELANSAAWQHSSSPSHPLKKEPGTKAAAAEASISLQDTPRSATTTTTAIATATTSAGHSDCSSHKSRPGPDPSPSKAKHQDRPLSSQKLSAGSAKGKEPVSQPIGGSVREGKGGSKGQSDTFSAIPATQGKASDVLDQGEGRVTIILHTEESLLDAKLKATNGGGPPEMQEKHLPRQGHPGLSEAADQKLLAAGEKQSLSPKHPKPSTVKDYPGLCRQTDKSPGQQATIGDRKAEGKKCTEALYVPAPEGYKLEASPSFHHGESGLKGAERPAVGMGKGFSESKGKGPCPQKPPAEAVKPGGMKRSPSATVQSSLRSAAPPEKSLSYSASFPEAQPGVREVTAASSSPSSAKAAVGTSEGPAPSSRDHRKSGGDSRNQMIKSDSLPSFRLSNSTLESHFQDPQVPSMAGHRDRALSVTAATGEPKGRELTQPPPVRKQNVGKDVTRAPPVPSADRSLPLSSEKDVVVRQRRGKESLRSSPQKKAS", "length": 2654 }, "evidence": [ { "id": "HGNC:19037", "url": "https://alliancegenome.org/gene/HGNC:19037#orthology", "database": "AGR" }, { "id": "MGI:1918885", "url": "https://alliancegenome.org/gene/MGI:1918885#orthology", "database": "AGR" }, { "id": "RGD:1310139", "url": "https://alliancegenome.org/gene/RGD:1310139#orthology", "database": "AGR" }, { "id": "FB:FBgn0267390", "url": "https://alliancegenome.org/gene/FB:FBgn0267390#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7F723-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "mast2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKKTESKNKRKLCTSEQQDSSTEGKDEELPAPPPLLFRKLSNPDLSPAAGKTKLQRQLSQDDSRGRRSSMAGILTGKQLLPLSSSMHGGVSQLAWQQHTGEPNNLVRMRSQSFGQSAPSLTAGLKELSLPRRGSFCRTSNRKSLIVTSSTSPTLPRPHSPLHGHPGSSPLDSPRNFSPNTAAHFSFVPARSHGHRADRTDGRRWSLASLPSSGYGTNTPSSTVSSSCSSQEKLHQLPFQPTADELHFLTKHFSSESITDEDGRRSPAMRPRSRSLSPGRSPISFDHEIVMMNHVYKERFPKATAQMEVRLADFISSSAPEKVMPLADGVLSFIHHQVIELSRDCLDKSREGLITSRYFYELQENLEKLHQDAHERSESGEVTFVTQLVKKLMIIIARPARLLECLEFDPEEFYHLLEAAEGHAKEGQGIKSDIPRYIISQLGLTRDPLEEMAQLSSYDSGNPETPETETDSTDSRGATVQPLQPQPQPQPKTKTPREEDFETIKLISNGAYGAVFLVRHKETRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKHIGALPVDMARMYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHVKLTDFGLSKIGLMSLTTNLYEGHIEKDTREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGVILYEFLVGCAPFFGDTPEELFGQVISDEIIWPEGDEALPPDAQDLISKLLRQNPLERLGTGSAFEVKQHRFFTDLDWNSLLRQKAEFIPQLESEDDTSYFDTRSDRYHHVDSEEEDDTNDDDHLEIRQFSSCSPRFSKVYSSMERLSLHEEKRTPPPTKRSLSEEGGERIDSLSGLKSRDRSWLVGSPEILRKRLSVSESSHTESDSSPPLTVRRRCCSAIIEMPRFAISSEEDSCVGSRKTPVRGPRGDDLPQAIPELPVERELRLDESPTTPGSTSSQISQSTLTPGSSGDVLDRASRYSAEVSENSTPRAISDLAARRARHRLLSGDTDKHTSRPLSKVIKSASATTLSLMIPADHHGASPLASPMSPHSLSSNPSSRDSSPSRDLSPAVCSVKPAIIIHRAGKKYGFTLRAIRVYMGDTDIYTVHHMVWHVEDGGPAHEAGLREGDLITHVNGEPVHGLVHTEVVELILKSGSKVSISATPFENTSIKVGPARKTSYKSKMARRNKRTKTREGQDSKKRNSLFRKITKQATLLHTSRSLSSLNRSVSSGESVPGSPTHMSPRSPTQGCRSTPDSAHSVGGNSSQSSSPSSSVPNSPASSGQIRPSSLHGLAPKLQRQYRSPRRKSAGNIPLSPLARTPSPTPQSTSPQRSPSPLPSHGLITSSIGQSFPVKLHSSPPLVRQISRPKSADPPRSPLLKRVQSAEKLAASLSSSSSSPSPSSAADKKLPVGASRKHSLDTSHSEFKKEMLQRDPSLQSLQESASETLMGGRVSPAEKGSLQKSSVRKLGRQEGPESGTGTLGLVPGKSKLKDKLSAIRAERRESLQKQDAIHEVDSSEDETDEGSEDSQDGRRTCYAPPSHVLRPTTVMASPHTIRMGPAAPPTLGLFPSTVAPPCSPQLIRGLQIQNQSTTQSQTQTSTSQPAQAAVKPPEQKPITSVKDSSSTIIDDSKKQSQAQDIQSRPSPHQPSPLSSTFSTQGSAFTSVSKDPFVKPTTPPLDPRRTPKMSEPRSKTSGRTDSSTTSGVARDTPVATTPTGGITKEMKEADNRRQAAAAAAASAAAATTSASTASESGMDKVVSQLATVAKSVLGPVKLNIPGTKETMERTKDQRTQADATHPKIKECRLEHPDSPDQLSPSAASGSQSPRLTESPSKQTSSKSEPASTSQRPLEVPGTFKRQTSPIPQAREEHQDRSGTLQSGTTSRPRSEAQSQTQQAKPSSTTSRDKSNKTT", "length": 1934 }, "evidence": [ { "id": "HGNC:19035", "url": "https://alliancegenome.org/gene/HGNC:19035#orthology", "database": "AGR" }, { "id": "MGI:894676", "url": "https://alliancegenome.org/gene/MGI:894676#orthology", "database": "AGR" }, { "id": "Q9VUQ9", "url": "https://omabrowser.org/oma/group/Q9VUQ9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O15021-5", "protein_name": "Microtubule-associated serine/threonine-protein kinase 4", "gene_name": "MAST4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGEKVSEAPEPVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELDHILSPPPMPFRKCSNPDVASGPGKSLKYKRQLSEDGRQLRRGSLGGALTGRYLLPNPVAGQAWPASAETSNLVRMRSQALGQSAPSLTASLKELSLPRRGSFCRTSNRKSLIGNGQSPALPRPHSPLSAHAGNSPQDSPRNFSPSASAHFSFARRTDGRRWSLASLPSSGYGTNTPSSTVSSSCSSQEKLHQLPYQPTPDELHFLSKHFCTTESIATENRCRNTPMRPRSRSLSPGRSPACCDHEIIMMNHVYKERFPKATAQMEERLKEIITSYSPDNVLPLADGVLSFTHHQIIELARDCLDKSHQGLITSRYFLELQHKLDKLLQEAHDRSESGELAFIKQLVRKILIVIARPARLLECLEFDPEEFYYLLEAAEGHAKEGQGIKTDIPRYIISQLGLNKDPLEEMAHLGNYDSGTAETPETDESVSSSNASLKLRRKPRESDFETIKLISNGAYGAVYFVRHKESRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVSMYCSFETRRHLCMVMEYVEGGDCATLMKNMGPLPVDMARMYFAETVLALEYLHNYGIVHRDLKPDNLLVTSMGHIKLTDFGLSKVGLMSMTTNLYEGHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEINWPEKDEAPPPDAQDLITLLLRQNPLERLGTGGAYEVKQHRFFRSLDWNSLLRQKAEFIPQLESEDDTSYFDTRSEKYHHMETEEEDDTNDEDFNVEIRQFSSCSHRFSKVFSSIDRITQNSAEEKEDSVDKTKSTTLPSTETLSWSSEYSEMQQLSTSNSSDTESNRHKLSSGLLPKLAISTEGEQDEAASCPGDPHEEPGKPALPPEECAQEEPEVTTPASTISSSTLSVGSFSEHLDQINGRSECVDSTDNSSKPSSEPASHMARQRLESTEKKKISGKVTKSLSASALSLMIPGDMFAVSPLGSPMSPHSLSSDPSSSRDSSPSRDSSAASASPHQPIVIHSSGKNYGFTIRAIRVYVGDSDIYTVHHIVWNVEEGSPACQAGLKAGDLITHINGEPVHGLVHTEVIELLLKSGNKVSITTTPFENTSIKTGPARRNSYKSRMVRRSKKSKKKESLERRRSLFKKLAKQPSPLLHTSRSFSCLNRSLSSGESLPGSPTHSLSPRSPTPSYRSTPDFPSGTNSSQSSSPSSSAPNSPAGSGHIRPSTLHGLAPKLGGQRYRSGRRKSAGNIPLSPLARTPSPTPQPTSPQRSPSPLLGHSLGNSKIAQAFPSKMHSPPTIVRHIVRPKSAEPPRSPLLKRVQSEEKLSPSYGSDKKHLCSRKHSLEVTQEEVQREQSQREAPLQSLDENVCDVPPLSRARPVEQGCLKRPVSRKVGRQESVDDLDRDKLKAKVVVKKADGFPEKQESHQKSHGPGSDLENFALFKLEEREKKVYPKAVERSSTFENKASMQEAPPLGSLLKDALHKQASVRASEGAMSDGRVPAEHRQGGGDFRRAPAPGTLQDGLCHSLDRGISGKGEGTEKSSQAKELLRCEKLDSKLANIDYLRKKMSLEDKEDNLCPVLKPKMTAGSHECLPGNPVRPTGGQQEPPPASESRAFVSSTHAAQMSAVSFVPLKALTGRVDSGTEKPGLVAPESPVRKSPSEYKLEGRSVSCLKPIEGTLDIALLSGPQASKTELPSPESAQSPSPSGDVRASVPPVLPSSSGKKNDTTSARELSPSSLKMNKSYLLEPWFLPPSRGLQNSPAVSLPDPEFKRDRKGPHPTARSPGTVMESNPQQREGSSPKHQDHTTDPKLLTCLGQNLHSPDLARPRCPLPPEASPSREKPGLRESSERGPPTARSERSAARADTCREPSMELCFPETAKTSDNSKNLLSVGRTHPDFYTQTQAMEKAWAPGGKTNHKDGPGEARPPPRDNSSLHSAGIPCEKELGKVRRGVEPKPEALLARRSLQPPGIESEKSEKLSSFPSLQKDGAKEPERKEQPLQRHPSSIPPPPLTAKDLSSPAARQHCSSPSHASGREPGAKPSTAEPSSSPQDPPKPVAAHSESSSHKPRPGPDPGPPKTKHPDRSLSSQKPSVGATKGKEPATQSLGGSSREGKGHSKSGPDVFPATPGSQNKASDGIGQGEGGPSVPLHTDRAPLDAKPQPTSGGRPLEVLEKPVHLPRPGHPGPSEPADQKLSAVGEKQTLSPKHPKPSTVKDCPTLCKQTDNRQTDKSPSQPAANTDRRAEGKKCTEALYAPAEGDKLEAGLSFVHSENRLKGAERPAAGVGKGFPEARGKGPGPQKPPTEADKPNGMKRSPSATGQSSFRSTALPEKSLSCSSSFPETRAGVREASAASSDTSSAKAAGGMLELPAPSNRDHRKAQPAGEGRTHMTKSDSLPSFRVSTLPLESHHPDPNTMGGASHRDRALSVTATVGETKGKDPAPAQPPPARKQNVGRDVTKPSPAPNTDRPISLSNEKDFVVRQRRGKESLRSSPHKKAL", "length": 2623 }, "evidence": [ { "id": "HGNC:19037", "url": "https://alliancegenome.org/gene/HGNC:19037#orthology", "database": "AGR" }, { "id": "MGI:1918885", "url": "https://alliancegenome.org/gene/MGI:1918885#orthology", "database": "AGR" }, { "id": "RGD:1310139", "url": "https://alliancegenome.org/gene/RGD:1310139#orthology", "database": "AGR" }, { "id": "FB:FBgn0267390", "url": "https://alliancegenome.org/gene/FB:FBgn0267390#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O60307-1", "protein_name": "Microtubule-associated serine/threonine-protein kinase 3", "gene_name": "MAST3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDESSLLRRRGLQKELSLPRRGRGCRSGNRKSLVVGTPSPTLSRPLSPLSVPTAGSSPLDSPRNFSAASALNFPFARRADGRRWSLASLPSSGYGTNTPSSTLSSSSSSRERLHQLPFQPTPDELHFLSKHFRSSENVLDEEGGRSPRLRPRSRSLSPGRATGTFDNEIVMMNHVYRERFPKATAQMEGRLQEFLTAYAPGARLALADGVLGFIHHQIVELARDCLAKSGENLVTSRYFLEMQEKLERLLQDAHERSDSEEVSFIVQLVRKLLIIISRPARLLECLEFDPEEFYHLLEAAEGHAREGQGIKTDLPQYIIGQLGLAKDPLEEMVPLSHLEEEQPPAPESPESRALVGQSRRKPCESDFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVFVERDILTFAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARLYFAETVLALEYLHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLYEGHIEKDAREFIDKQVCGTPEYIAPEVIFRQGYGKPVDWWAMGVVLYEFLVGCVPFFGDTPEELFGQVVSDEIMWPEGDEALPADAQDLITRLLRQSPLDRLGTGGTHEVKQHPFFLALDWAGLLRHKAEFVPQLEAEDDTSYFDTRSERYRHLGSEDDETNDEESSTEIPQFSSCSHRFSKVYSSSEFLAVQPTPTFAERSFSEDREEGWERSEVDYGRRLSADIRLRSWTSSGSSCQSSSSQPERGPSPSLLNTISLDTMPKFAFSSEDEGVGPGPAGPKRPVFILGEPDPPPAATPVMPKPSSLSADTAALSHARLRSNSIGARHSTPRPLDAGRGRRLGGPRDPAPEKSRASSSGGSGGGSGGRVPKSASVSALSLIITADDGSGGPLMSPLSPRSLSSNPSSRDSSPSRDPSPVCGSLRPPIVIHSSGKKYGFSLRAIRVYMGDSDVYTVHHVVWSVEDGSPAQEAGLRAGDLITHINGESVLGLVHMDVVELLLKSGNKISLRTTALENTSIKVGPARKNVAKGRMARRSKRSRRRETQDRRKSLFKKISKQTSVLHTSRSFSSGLHHSLSSSESLPGSPTHSLSPSPTTPCRSPAPDVPADTTASPPSASPSSSSPASPAAAGHTRPSSLHGLAAKLGPPRPKTGRRKSTSSIPPSPLACPPISAPPPRSPSPLPGHPPAPARSPRLRRGQSADKLGTGERLDGEAGRRTRGPEAELVVMRRLHLSERRDSFKKQEAVQEVSFDEPQEEATGLPTSVPQIAVEGEEAVPVALGPTGRD", "length": 1309 }, "evidence": [ { "id": "HGNC:19036", "url": "https://alliancegenome.org/gene/HGNC:19036#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040914-35", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040914-35#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-111209-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-111209-1#orthology", "database": "AGR" }, { "id": "MGI:2683541", "url": "https://alliancegenome.org/gene/MGI:2683541#orthology", "database": "AGR" }, { "id": "RGD:1587639", "url": "https://alliancegenome.org/gene/RGD:1587639#orthology", "database": "AGR" }, { "id": "FB:FBgn0267390", "url": "https://alliancegenome.org/gene/FB:FBgn0267390#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3U214-1", "protein_name": "Microtubule-associated serine/threonine-protein kinase 3", "gene_name": "Mast3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKSRREKLLIPALTLDLSPSSQSPCLLSPGSPCSPCSPSLGLQPWSCRSGNRKSLVVGTPSPTLSRPLSPLSVPTAGNSPLDSPRNFSAAAAISFPFARRADGRRWSLASLPSSGYGTNTPSSTVSSSSSSRERLHQLPFQPTADELRFLSKHFRSSESVVDEDGGRSPRLRPRSRSLSPGRTSGTFDNEIVMMNHVYRERFPKATAQMEGRLQDFLAAFAPGDRLALADGVLGFIHHQIVELARDCLAKSGEALVTSRYFLEMQDKLERLLQDAHERSDSAEVGFIVQLVRKLLIIISRPARLLECLEFDPEEFYHLLEAAEGQAREDQGVKTDLPRYIIRQLGLAKDPLEEIQPLNDLDESQPPAPGSPESRGLGGPSRRKPCESDFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVFVERDILTFAENPFVVGMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARMYFAETVLALEYLHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLYEGHIEKDAREFVDKQVCGTPEYIAPEVIFRQGYGKPVDWWAMGVILYEFLVGCVPFFGDTPEELFGQVVSDEIMWPEGDEALPLDAQDLITRLLRQSPMDRLGTGGTHEVKQHPFFLALDWAGLLRHKAEFVPQLEAEDDTSYFDTRSERYRHLGSEDDETNDEESSTEIPQFSSCSHRFSKVYSSSEFLAVQPTPTFAERSFSEDREDGWGQSLGDRGRRLSADLRLRSWTPASSCQPSSCQTDRGPSPSLLSTISLDVMPKFAFSSEDEGASSGPADPQKPVFILGEPDPPPPTTPVTPKPCNLSADTAVLSHARLRSNSTGARHSTPRPLDAGRGRRLGGSRDPGPEKPRASPGGSGGRVPKSASVSALSLIITADDGSGGPLMSPLSPRSLSSNPSSRDSSPSRDPSPVCGSLRPPIVIHSSGKKYGFSLRAIRVYMGDSDVYTVHHVVWSVEEGSPAQEAGLRAGDLITHINGESVLGLVHMDVVELLLKSGNKISLRTTALENTSIKVGPARKNVAKGRMARRSKRSRRRETQDRRKSLFKRISKPSSVLHTSRSFSSGLQHSLSSSESLPGSPTHSLSPSPTTPCRSPAPDAPTDTASPPNVSPSSSSPASPATGHTRPSSLHGLAAKLGPPRHKSGRRKSTSSIPPSPLACPPVPTPPPRSPSPLPGHIPIPARSPRLRRGQSADKLGLGTSERLDGDGGRRARGAEAELVVMRRLHLSERRDSFKKQEAVQEVSFDEEPGPPRGVPKIAVQGAEATPGTPGHARKD", "length": 1321 }, "evidence": [ { "id": "HGNC:19036", "url": "https://alliancegenome.org/gene/HGNC:19036#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040914-35", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040914-35#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-111209-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-111209-1#orthology", "database": "AGR" }, { "id": "MGI:2683541", "url": "https://alliancegenome.org/gene/MGI:2683541#orthology", "database": "AGR" }, { "id": "RGD:1587639", "url": "https://alliancegenome.org/gene/RGD:1587639#orthology", "database": "AGR" }, { "id": "FB:FBgn0267390", "url": "https://alliancegenome.org/gene/FB:FBgn0267390#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q60592-1", "protein_name": "Microtubule-associated serine/threonine-protein kinase 2", "gene_name": "Mast2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVTGLSPLLFRKLSNPDIFAPTGKVKLQRQLSQDDCKLRRGSLASSLSGKQLLPLSSSVHSSVGQVTWQSTGEASNLVRMRNQSLGQSAPSLTAGLKELSLPRRGSFCRTSNRKSLIVTSSTSPTLPRPHSPLHGHTGNSPLDSPRNFSPNAPAHFSFVPARRTDGRRWSLASLPSSGYGTNTPSSTVSSSCSSQEKLHQLPFQPTADELHFLTKHFSTENVPDEEGRRSPRMRPRSRSLSPGRSPVSFDSEIIMMNHVYKERFPKATAQMEERPSLTFISSNTPDSVLPLADGALSFIHHQVIEMARDCLDKSRSGLITSHYFYELQENLEKLLQDAHERSESSDVAFVIQLVKKLMIIIARPARLLECLEFDPEEFYHLLEAAEGHAKEGHGIKCDIPRYIVSQLGLTRDPLEEMAQLSSYDSPDTPETDDSVEGRGVSQPSQKTPSEEDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVSMFCSFETKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKIGLMSLTTNLYEGHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEIVWPEGDDALPPDAQDLTSKLLHQNPLERLGTSSAYEVKQHPFFMGLDWTGLLRQKAEFIPQLESEDDTSYFDTRSERYHHVDSEDEEEVSEDGCLEIRQFSSCSPRFSKVYSSMERLSLLEERRTPPPTKRSLSEEKEDHSDGLAGLKGRDRSWVIGSPEILRKRLSVSESSHTESDSSPPMTVRHRCSGLPDGPHCPEETSSTPRKQQQEGIWVLIPPSGEGSSRPVPERPLERQLKLDEEPPGQSSRCCPALETRGRGTPQLAEEATAKAISDLAVRRARHRLLSGDSIEKRTTRPVNKVIKSASATALSLLIPSEHHACSPLASPMSPHSQSSNPSSRDSSPSRDFLPALGSLRPPIIIHRAGKKYGFTLRAIRVYMGDTDVYTVHHMVWHVEDGGPASEAGLRQGDLITHVNGEPVHGLVHTEVVELVLKSGNKVSISTTPLENTSIKVGPARKGSYKAKMARRSKRSKGKDGQESRKRSSLFRKITKQASLLHTSRSLSSLNRSLSSGESGPGSPTHSHSLSPRSPPQGYRVAPDAVHSVGGNSSQSSSPSSSVPSSPAGSGHTRPSSLHGLAPKLQRQYRSPRRKSAGSIPLSPLAHTPSPPATAASPQRSPSPLSGHGSQSFPTKLHLSPPLGRQLSRPKSAEPPRSPLLKRVQSAEKLAAALAAAEKKLAPSRKHSLDLPHGELKKELTPREASPLEVVGTRSVLSGKGPLPGKGVLQPAPSRALGTLRQDRAERRESLQKQEAIREVDSSEDDTDEEPENSQATQEPRLSPHPEASHNLLPKGSGEGTEEDTFLHRDLKKQGPVLSGLVTGATLGSPRVDVPGLSPRKVSRPQAFEEATNPLQVPSLSRSGPTSPTPSEGCWKAQHLHTQALTALCPSFSELTPTGCSAATSTSGKPGTWSWKFLIEGPDRASTNKTITRKGEPANSQDTNTTVPNLLKNLSPEEEKPQPPSVPGLTHPLLEVPSQNWPWESECEQMEKEEPSLSITEVPDSSGDRRQDIPCRAHPLSPETRPSLLWKSQELGGQQDHQDLALTSDELLKQT", "length": 1734 }, "evidence": [ { "id": "HGNC:19035", "url": "https://alliancegenome.org/gene/HGNC:19035#orthology", "database": "AGR" }, { "id": "MGI:894676", "url": "https://alliancegenome.org/gene/MGI:894676#orthology", "database": "AGR" }, { "id": "RGD:1304573", "url": "https://alliancegenome.org/gene/RGD:1304573#orthology", "database": "AGR" }, { "id": "FB:FBgn0267390", "url": "https://alliancegenome.org/gene/FB:FBgn0267390#orthology", "database": "AGR" }, { "id": "Q9VUQ9", "url": "https://omabrowser.org/oma/group/Q9VUQ9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6P0Q8-1", "protein_name": "Microtubule-associated serine/threonine-protein kinase 2", "gene_name": "MAST2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKRSRCRDRPQPPPPDRREDGVQRAAELSQSLPPRRRAPPGRQRLEERTGPAGPEGKEQDVVTGVSPLLFRKLSNPDIFSSTGKVKLQRQLSQDDCKLWRGNLASSLSGKQLLPLSSSVHSSVGQVTWQSSGEASNLVRMRNQSLGQSAPSLTAGLKELSLPRRGSFCRTSNRKSLIVTSSTSPTLPRPHSPLHGHTGNSPLDSPRNFSPNAPAHFSFVPARRTDGRRWSLASLPSSGYGTNTPSSTVSSSCSSQEKLHQLPFQPTADELHFLTKHFSTESVPDEEGRQSPAMRPRSRSLSPGRSPVSFDSEIIMMNHVYKERFPKATAQMEERLAEFISSNTPDSVLPLADGALSFIHHQVIEMARDCLDKSRSGLITSQYFYELQDNLEKLLQDAHERSESSEVAFVMQLVKKLMIIIARPARLLECLEFDPEEFYHLLEAAEGHAKEGQGIKCDIPRYIVSQLGLTRDPLEEMAQLSSCDSPDTPETDDSIEGHGASLPSKKTPSEEDFETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMVRLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKIGLMSLTTNLYEGHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEIVWPEGDEALPPDAQDLTSKLLHQNPLERLGTGSAYEVKQHPFFTGLDWTGLLRQKAEFIPQLESEDDTSYFDTRSERYHHMDSEDEEEVSEDGCLEIRQFSSCSPRFNKVYSSMERLSLLEERRTPPPTKRSLSEEKEDHSDGLAGLKGRDRSWVIGSPEILRKRLSVSESSHTESDSSPPMTVRRRCSGLLDAPRFPEGPEEASSTLRRQPQEGIWVLTPPSGEGVSGPVTEHSGEQRPKLDEEAVGRSSGSSPAMETRGRGTSQLAEGATAKAISDLAVRRARHRLLSGDSTEKRTARPVNKVIKSASATALSLLIPSEHHTCSPLASPMSPHSQSSNPSSRDSSPSRDFLPALGSMRPPIIIHRAGKKYGFTLRAIRVYMGDSDVYTVHHMVWHVEDGGPASEAGLRQGDLITHVNGEPVHGLVHTEVVELILKSGNKVAISTTPLENTSIKVGPARKGSYKAKMARRSKRSRGKDGQESRKRSSLFRKITKQASLLHTSRSLSSLNRSLSSGESGPGSPTHSHSLSPRSPTQGYRVTPDAVHSVGGNSSQSSSPSSSVPSSPAGSGHTRPSSLHGLAPKLQRQYRSPRRKSAGSIPLSPLAHTPSPPPPTASPQRSPSPLSGHVAQAFPTKLHLSPPLGRQLSRPKSAEPPRSPLLKRVQSAEKLAAALAASEKKLATSRKHSLDLPHSELKKELPPREVSPLEVVGARSVLSGKGALPGKGVLQPAPSRALGTLRQDRAERRESLQKQEAIREVDSSEDDTEEGPENSQGAQELSLAPHPEVSQSVAPKGAGESGEEDPFPSRDPRSLGPMVPSLLTGITLGPPRMESPSGPHRRLGSPQAIEEAASSSSAGPNLGQSGATDPIPPEGCWKAQHLHTQALTALSPSTSGLTPTSSCSPPSSTSGKLSMWSWKSLIEGPDRASPSRKATMAGGLANLQDLENTTPAQPKNLSPREQGKTQPPSAPRLAHPSYEDPSQGWLWESECAQAVKEDPALSITQVPDASGDRRQDVPCRGCPLTQKSEPSLRRGQEPGGHQKHRDLALVPDELLKQT", "length": 1798 }, "evidence": [ { "id": "HGNC:19035", "url": "https://alliancegenome.org/gene/HGNC:19035#orthology", "database": "AGR" }, { "id": "MGI:894676", "url": "https://alliancegenome.org/gene/MGI:894676#orthology", "database": "AGR" }, { "id": "RGD:1304573", "url": "https://alliancegenome.org/gene/RGD:1304573#orthology", "database": "AGR" }, { "id": "FB:FBgn0267390", "url": "https://alliancegenome.org/gene/FB:FBgn0267390#orthology", "database": "AGR" }, { "id": "Q9VUQ9", "url": "https://omabrowser.org/oma/group/Q9VUQ9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q810W7-1", "protein_name": "Microtubule-associated serine/threonine-protein kinase 1", "gene_name": "Mast1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSDSLWTALSNFSMPSFPGGSMFRRTKSCRTSNRKSLILTSTSPTLPRPHSPLPGHLGSSPLDSPRNFSPNTPAHFSFASSRRADGRRWSLASLPSSGYGTNTPSSTVSSSCSSQERLHQLPYQPTVDELHFLSKHFGSTESITDEDGGRRSPAVRPRSRSLSPGRSPSSYDNEIVMMNHVYKERFPKATAQMEEKLRDFARAYEPDSVLPLADGVLSFIHHQIIELARDCLTKSRDGLITTVYFYELQENLEKLLQDAYERSESLEVAFVTQLVKKLLIIISRPARLLECLEFNPEEFYHLLEAAEGHAKEGHLVKTDIPRYIIRQLGLTRDPFPDVVRLEEQDSGGSNTPEQDDTSEGRSSTSKAKKPPGESDFDTIKLISNGAYGAVYLVRHRDTRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVGMFCSFETRRHLCMVMEYVEGGDCATLLKNIGALPVEMARMYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKMGLMSLTTNLYEGHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDDILWPEGDEALPTDAQLLISSLLQTNPLVRLGAGGAFEVKQHSFFRDLDWTGLLRQKAEFIPHLESEDDTSYFDTRSDRYHHVNSYDEDDTTEEEPVEIRQFSSCSPRFSKVYSSMEQLSQHEPKTPVSASGASKRDPNAKGPEEKVAGKREGLGGLTLREKTWRGGSPEIKRFSASEASFLEGEASPPLGARRRFSALLEPSRFTAPQEDEDEARLRRPPRPSSDPPSSLDTRVPKEAAQGEGTSTPGEPEATERSHPGDFCPPSKDGDPSGPRATNDLVLRRARHQQLSGDLSVEKRPSRTGGKVIKSASATALSVMIPAVDPHGGSPLASPMSPRSLSSNPSSRDSSPSRDYSPAVSGLRSPITIQRSGKKYGFTLRAIRVYMGDSDVYSVHHIVWHVEEGGPAQEAGLCAGDLITHVNGEPVHGMVHPEVVELILKSGNKVAVTTTPFENTSIRIGPARRSSYKAKMARRNKRPSAKDGQESKKRSSLFRKITKQSNLLHTSRSLSSLNRSLSSSDSLPGSPTHGLPARSPTHSYRSTPDSAYLGASSQSSSPASSTPNSPASSASHHIRPSTLHGLSPKLHRQYRSARCKSAGNIPLSPLAHTPSPTQASPPPLPGHTVGSSHTTQSFPAKLHSSPPIVRPRPKSAEPPRSPLLKRVQSAEKLGASLGADKKGALRKHSLEVGHPDFRKDFHGELALHSLAESDGETPPIEGPGATRQVAMRRLGRQESPLSLGADPLLPDGVQRPMASGKEDSAGGTEACTPPRATTPGSRTLERDLGCTRHQSVQTEDGPGGVARALAKAALSPVQEHETGRRSSSGEAGTPPVPIVVEPARPGVKTQTPQPLGTDSKGLKEPVAQIPLVPDAPRVRERWVLEEVEERTTLSGPRSKPASPKLSPDPQTPTVAPTKNVPRSAAPPVPPASLMVPGTKPEAGSNSRCPAEGVASAGLTKTGAPSPASLGP", "length": 1570 }, "evidence": [ { "id": "HGNC:19034", "url": "https://alliancegenome.org/gene/HGNC:19034#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121214-221", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121214-221#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131025-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131025-2#orthology", "database": "AGR" }, { "id": "MGI:1861901", "url": "https://alliancegenome.org/gene/MGI:1861901#orthology", "database": "AGR" }, { "id": "RGD:631372", "url": "https://alliancegenome.org/gene/RGD:631372#orthology", "database": "AGR" }, { "id": "FB:FBgn0267390", "url": "https://alliancegenome.org/gene/FB:FBgn0267390#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q811L6-1", "protein_name": "Microtubule-associated serine/threonine-protein kinase 4", "gene_name": "Mast4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGEKVSEAPEPVPRGCSGHGARTLVSSAAAVSSEGASSAESSSGSETLSEEGEPSRFSCRSQPPRPPGGALGTRLPAAWAPARVALERGVPTLPLPHPGGAVLPVPQVSSASQEEQDEELDHILSPPPMPFRKCSNPDVACGLGKSLKYKRQLSEDGKQLRRGSLGGALTGRYLLPNPVAGQAWPASAETSNLVRMRSQALGQSAPSLTASLKELSLPRRGSLCRTSNRKSLIGNGQSPALPRPHSPLSAHAGNSPQDSPRNFSPSASAHFSFARRTDGRRWSLASLPSSGYGTNTPSSTVSSSCSSQEKLHQLPYQPTPDELHFLSKHFCTTESIATENRCRNTPMRPRSRSLSPGRSPACCDHEIIMMNHVYKERFPKATAQMEERLKEIITSYSPDHVLPLADGVLSFTHHQIIELARDCLDKSHQGLITSRYFFELQHKLDKLLQEAHDRSESGELAFIKQLVRKILIVIARPARLLECLEFDPEEFYYLLEAAEGHAKEGQGIKTDIPRYIISQLGLNKDPLEEMAQLGNYDSRTAETPEMDESVSSSNTSLRLRRKPRESDFETIKLISNGAYGAVYFVRHKESRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVSMYCSFETRRHLCMVMEYVEGGDCATLMKNMGPLPVDMARMYFAETVLALEYLHNYGIVHRDLKPDNLLVTSMGHIKLTDFGLSKVGLMSMTTNLYEGHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEINWPEKDEAPPPDAQELITLLLRQNPLERLGTGGAYEVKQHRFFRSLDWNSLLRQKAEFIPQLESEDDTSYFDTRSEKYHHMETEEEDDTNDEDFTVEIRQFSSCSHRFSKVFSSIDRITQNSGEDKDDSEDKTKSTTLPSTETLSWSSEYSEMQQLSTSNSSDTESNRCKLSSGLLPKLAISTDGEQDEAVPCSGDPREEPEKPVPPSEECTQEEPEVTTPASTISSSTLSVGSFSEHLDQINGRSECVDSTDNSSKPSSEPTSHVARQRLESTEKKKISGKVTKSLSASALSLMIPGDMFAVSPLGSPMSPHSLSSDPSSSRDSSPSRDSSAASASPHQPIVIHSSGKNYGFTIRAIRVYVGDSDIYTVHHIVWNVEEGSPAYQAGLKAGDLITHINGEPVHGLVHTEVIELLLKSGNKVSITTTPFENTSIKTGPARRNSYKGRMVRRSKKSKKKESLERRRSLFKKLAKQPSPLLHTSRSFSCLNRSLSSGESLPGSPTHSLSPRSPTPSYRSTPDFPSGTNSSQSSSPSSSAPNSPAGSGHIRPSTLHGLAPKLSGQRYRSGRRKSAGSIPLSPLARTPSPTPQPTSPQRSPSPLLGHSLGNAKITQAFPSKMHSPPTIVRHIVRPKSAEPPRSPLLKRVQSEEKLSPSYGSDKKLLCSRKHSLEVTQEEVQREQCQREVTLQSLEENVCDAPSLSRARPVEQGCLKRPVSRKVGRQESVDDLDRDKLKAKVVVKKPEEKHESHQKPHSLGGDSESYALFRLEEREKKVYSKGLERSGHFENTSAELPSVGSLLKDTLHKQASVRASEGVTSDGAACSLTPGEHSQSLGDFKRASASGILHDSVCPISDRPAPGKVEYSEKASQAKELLRSEKLDSKLANIDYLRKKMSLDDKDDSHCAILKPKITSSAHECLPGNPIRPMAGQQETPPASENRAFINSTHTPQMSAVSFVPLKALAGRVENGGEKAGLAAPESPVRKSPSEYKLEGRSVSCLKPIEGTLDIALLSGPHASKTELLSPEPAQSPSPGINVGPCVPLALPGSSGKKGDSTSLREPSSANLKVNKSYLLEPRFLPPSRALQDSLAASGPEPKSKPERKLIHPSARSPATVTESNLQQKEGGPATHQDRSTDTRNLPGPGQTLHNVDLPRLCTRAPLPPEGTPAKEKPCLKEPSAKVKSEWSAVRDDGHRDPCAKLCPAETGKASDSSKPLPSGGRTQPDFYKQTQTSEKAWAHAKTNHKDSQDEVKSLAREDSASLLYEKEIGRARKGPEPKPEVPATRCPPQPPGIEGEKREKLSAAPSLQKQAPKEPDRKEQTSQRPGGSGPQQPPPTKELSNSASWQHGSSPSHTLKKEPGTKAAAAEPSTSLHDTPRSATATTTAIATTTTTTSAGHSDCSSHKARPGPDPSPSKSKHQDRSLSSQKLSAGSAKGKEPVTQPLGGSIREGKGGSKGPVDTFSAVLTTQGKASDVLVQGEGRVSIIVHTEECPLDAKLKNTNGGCPPEMQAKHPPRQGHLSEAADQKPLIAGEKQSPSPKHPKPSTVKDYPSLCRQTDRSPSHQATTGDRKAEGKKCTDALYVAAPEGYKPEASPSLHHGETGLRGSERPPMGMGKGFSEPKGKGPGPQKSLAETGKPSGMKRSPSATVQSSLRSAAPPEKSLSYSASFPEAQPGVREVPAANSSPSSAKATGGTSEFPAPSSRDHRKLQSGGDGRSQMIKSDSLPSFRLSTSALESHFQDPQVPIASGHRGRALSVTAATGEPKGRELAQPPPVRKQNACREATRAPPAPSTDRSLPLSSEKDFVVRQRRGKETLRSSPHKKAS", "length": 2618 }, "evidence": [ { "id": "HGNC:19037", "url": "https://alliancegenome.org/gene/HGNC:19037#orthology", "database": "AGR" }, { "id": "MGI:1918885", "url": "https://alliancegenome.org/gene/MGI:1918885#orthology", "database": "AGR" }, { "id": "RGD:1310139", "url": "https://alliancegenome.org/gene/RGD:1310139#orthology", "database": "AGR" }, { "id": "FB:FBgn0267390", "url": "https://alliancegenome.org/gene/FB:FBgn0267390#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9R1L5-1", "protein_name": "Microtubule-associated serine/threonine-protein kinase 1", "gene_name": "Mast1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDSLWTALSNFSMPSFPGGSMFRRTKSCRTSNRKSLILTSTSPTLPRPHSPLPGHLGSSPLDSPRNFSPNTPAHFSFASSRRADGRRWSLASLPSSGYGTNTPSSTVSSSCSSQERLHQLPYQPTVDELHFLSKHFGSTESITDEDGGRRSPAVRPRSRSLSPGRSPSSYDNEIVMMNHVYKERFPKATAQMEEKLRDFARAYEPDSVLPLADGVLSFIHHQIIELARDCLTKSRDGLITTVYFYELQENLEKLLQDAYERSESLEVAFVTQLVKKLLIIISRPARLLECLEFNPEEFYHLLEAAEGHAKEGHLVKTDIPRYIIRQLGLTRDPFPDVVRLEEQDSGGSNTPEQDDTSEGRSSTSKAKKPPGESDFDTIKLISNGAYGAVYLVRHRDTRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVGMFCSFETRRHLCMVMEYVEGGDCATLLKNIGALPVEMARMYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKMGLMSLTTNLYEGHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDDILWPEGDEALPTDAQLLISSLLQTNPLVRLGAGGAFEVKQHSFFRDLDWTGLLRQKAEFIPHLESEDDTSYFDTRSDRYHHVNSYDEDDTTEEEPVEIRQFSSCSPRFSKVYSSMEQLSQHEPKTPVSASGASKRDPSAKGPEEKVAGKREGLGGLTLREKTWRGGSPEIKRFSASEASFLEGEASPPLGARRRFSALLEPSRFTAPQEDEDEARLRRPPRPSSDPPSSLDTRVPKEAVQGEGTSTPGEPEATERSHPGDLGPPSKDGDPSGPRATNDLVLRRARHQQLSGDLAVEKRPSRTGGKVIKSASATALSVMIPAVDPHGGSPLASPMSPRSLSSNPSSRDSSPSRDYSPAVSGLRSPITIQRSGKKYGFTLRAIRVYMGDSDVYSVHHIVWHVEEGGPAQEAGLCAGDLITHVNGEPVHGMVHPEVVELILKSGNKVAVTTTPFENTSIRIGPARRSSYKAKMARRNKRPSAKDGQESKKRSSLFRKITKQSNLLHTSRSLSSLNRSLSSSDSLPGSPTHGLPARSPTHSYRSTPDSAYLGASSQSSSPASSTPNSPASSASHHIRPSTLHGLSPKLHRQYRSARCKSAGNIPLSPLAHTPSPTQASPPPLPGHTVGSSHTTQSFPAKLHSSPPVVRPRPKSAEPPRSPLLKRVQSAEKLGASLGADKKGALRKHSLEVGHPDFRKDFHGELALHSLAESDGETPPIEGPGATRQVAVRRLGRQESPLSLGADPLLPDGVQRPMASSKEDSAGGTEACTPPRATTPGSRTLERDSGCTRHQSVQTEDGPGGVARALAKAALSPVQEHETGRRSSSGEAGTPPVPIVVEPARPGVKTQAPQPLGTDSKGLKEPVAQMPLMPDAPRGRERWVLEEVEERTTLSGLRSKPASPKLSPDPQTPTLVPTKNVPRSAAPSVPPASLMVPGTKPEAGLNSRCPAEAVTPAGLTKTGAPSPASLGP", "length": 1570 }, "evidence": [ { "id": "HGNC:19034", "url": "https://alliancegenome.org/gene/HGNC:19034#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121214-221", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121214-221#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131025-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131025-2#orthology", "database": "AGR" }, { "id": "MGI:1861901", "url": "https://alliancegenome.org/gene/MGI:1861901#orthology", "database": "AGR" }, { "id": "RGD:631372", "url": "https://alliancegenome.org/gene/RGD:631372#orthology", "database": "AGR" }, { "id": "FB:FBgn0267390", "url": "https://alliancegenome.org/gene/FB:FBgn0267390#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y2H9-1", "protein_name": "Microtubule-associated serine/threonine-protein kinase 1", "gene_name": "MAST1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSDSLWTALSNFSMPSFPGGSMFRRTKSCRTSNRKSLILTSTSPTLPRPHSPLPGHLGSSPLDSPRNFSPNTPAHFSFASSRRADGRRWSLASLPSSGYGTNTPSSTVSSSCSSQERLHQLPYQPTVDELHFLSKHFGSTESITDEDGGRRSPAVRPRSRSLSPGRSPSSYDNEIVMMNHVYKERFPKATAQMEEKLRDFTRAYEPDSVLPLADGVLSFIHHQIIELARDCLTKSRDGLITTVYFYELQENLEKLLQDAYERSESLEVAFVTQLVKKLLIIISRPARLLECLEFNPEEFYHLLEAAEGHAKEGHLVKTDIPRYIIRQLGLTRDPFPDVVHLEEQDSGGSNTPEQDDLSEGRSSKAKKPPGENDFDTIKLISNGAYGAVYLVRHRDTRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVGMFCSFETRRHLCMVMEYVEGGDCATLLKNIGALPVEMARMYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKMGLMSLTTNLYEGHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDDILWPEGDEALPTEAQLLISSLLQTNPLVRLGAGGAFEVKQHSFFRDLDWTGLLRQKAEFIPHLESEDDTSYFDTRSDRYHHVNSYDEDDTTEEEPVEIRQFSSCSPRFSKVYSSMEQLSQHEPKTPVAAAGSSKREPSTKGPEEKVAGKREGLGGLTLREKTWRGGSPEIKRFSASEASFLEGEASPPLGARRRFSALLEPSRFSAPQEDEDEARLRRPPRPSSDPAGSLDARAPKEETQGEGTSSAGDSEATDRPRPGDLCPPSKDGDASGPRATNDLVLRRARHQQMSGDVAVEKRPSRTGGKVIKSASATALSVMIPAVDPHGSSPLASPMSPRSLSSNPSSRDSSPSRDYSPAVSGLRSPITIQRSGKKYGFTLRAIRVYMGDTDVYSVHHIVWHVEEGGPAQEAGLCAGDLITHVNGEPVHGMVHPEVVELILKSGNKVAVTTTPFENTSIRIGPARRSSYKAKMARRNKRPSAKEGQESKKRSSLFRKITKQSNLLHTSRSLSSLNRSLSSSDSLPGSPTHGLPARSPTHSYRSTPDSAYLGASSQSSSPASSTPNSPASSASHHIRPSTLHGLSPKLHRQYRSARCKSAGNIPLSPLAHTPSPTQASPPPLPGHTVGSSHTTQSFPAKLHSSPPVVRPRPKSAEPPRSPLLKRVQSAEKLGASLSADKKGALRKHSLEVGHPDFRKDFHGELALHSLAESDGETPPVEGLGAPRQVAVRRLGRQESPLSLGADPLLPEGASRPPVSSKEKESPGGAEACTPPRATTPGGRTLERDVGCTRHQSVQTEDGTGGMARAVAKAALSPVQEHETGRRSSSGEAGTPLVPIVVEPARPGAKAVVPQPLGADSKGLQEPAPLAPSVPEAPRGRERWVLEVVEERTTLSGPRSKPASPKLSPEPQTPSLAPAKCSAPSSAVTPVPPASLLGSGTKPQVGLTSRCPAEAVPPAGLTKKGVSSPAPPGP", "length": 1570 }, "evidence": [ { "id": "HGNC:19034", "url": "https://alliancegenome.org/gene/HGNC:19034#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121214-221", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121214-221#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131025-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131025-2#orthology", "database": "AGR" }, { "id": "MGI:1861901", "url": "https://alliancegenome.org/gene/MGI:1861901#orthology", "database": "AGR" }, { "id": "RGD:631372", "url": "https://alliancegenome.org/gene/RGD:631372#orthology", "database": "AGR" }, { "id": "FB:FBgn0267390", "url": "https://alliancegenome.org/gene/FB:FBgn0267390#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "Q9VUQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VUQ9" } ], "pmid": "" }, { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "Q9VUQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VUQ9" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "Q9VUQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VUQ9" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VUQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VUQ9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VUQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VUQ9" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "Q9VUQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VUQ9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 10, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "Q9VUQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VUQ9" } ], "pmid": "" }, { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "Q9VUQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VUQ9" } ], "pmid": "" }, { "name": "endosome organization", "id": "GO:0007032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007032", "evidence": [ { "database": "UniProtKB", "id": "Q9VUQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VUQ9" } ], "pmid": "" }, { "name": "positive regulation of cell size", "id": "GO:0045793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045793", "evidence": [ { "database": "UniProtKB", "id": "Q9VUQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VUQ9" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "Q9VUQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VUQ9" } ], "pmid": "" }, { "name": "border follicle cell migration", "id": "GO:0007298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007298", "evidence": [ { "database": "UniProtKB", "id": "Q9VUQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VUQ9" } ], "pmid": "" }, { "name": "cellularization", "id": "GO:0007349", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007349", "evidence": [ { "database": "UniProtKB", "id": "Q9VUQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VUQ9" } ], "pmid": "" }, { "name": "dosage compensation by hyperactivation of X chromosome", "id": "GO:0009047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009047", "evidence": [ { "database": "UniProtKB", "id": "Q9VUQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VUQ9" } ], "pmid": "" }, { "name": "lipid droplet transport along microtubule", "id": "GO:0031887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031887", "evidence": [ { "database": "UniProtKB", "id": "Q9VUQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VUQ9" } ], "pmid": "" }, { "name": "wing disc development", "id": "GO:0035220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035220", "evidence": [ { "database": "UniProtKB", "id": "Q9VUQ9", "url": "https://www.uniprot.org/uniprotkb/Q9VUQ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 104, "end_pos": 106, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1287, "end_pos": 1289, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1323, "end_pos": 1325, "annotation": "n_glycosylation_sequon" }, { "start_pos": 143, "end_pos": 145, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1479, "end_pos": 1481, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1665, "end_pos": 1667, "annotation": "n_glycosylation_sequon" }, { "start_pos": 166, "end_pos": 168, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1683, "end_pos": 1685, "annotation": "n_glycosylation_sequon" }, { "start_pos": 170, "end_pos": 172, "annotation": "n_glycosylation_sequon" }, { "start_pos": 179, "end_pos": 181, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1807, "end_pos": 1809, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1858, "end_pos": 1860, "annotation": "n_glycosylation_sequon" }, { "start_pos": 270, "end_pos": 272, "annotation": "n_glycosylation_sequon" }, { "start_pos": 29, "end_pos": 31, "annotation": "n_glycosylation_sequon" }, { "start_pos": 395, "end_pos": 397, "annotation": "n_glycosylation_sequon" }, { "start_pos": 502, "end_pos": 504, "annotation": "n_glycosylation_sequon" }, { "start_pos": 568, "end_pos": 570, "annotation": "n_glycosylation_sequon" }, { "start_pos": 58, "end_pos": 60, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O61267-1", "P13677-1", "P23573-1", "P51123-1", "Q00168-1", "Q23977-1", "Q24210-3", "Q9VKN7-1", "O62618-1", "P10676-1", "P18431-2", "P23647-1", "P52304-1", "P83104-1", "Q03042-1", "Q70PP2-1", "Q8T0S6-1", "P83099-1", "Q9NIV1-1", "O76324-1", "P13678-1", "P16912-1", "P23572-1", "P40417-3", "P48609-1", "P49071-1", "P54367-1", "P83100-1", "P83102-1", "P92208-1", "Q03043-1", "Q0KHT7-1", "Q24324-1", "Q5EAK6-1", "P12370-1", "Q05652-1", "Q9VXE5-1", "P83103-1", "P54360-1", "Q7KRY6-1", "Q95UN8-1", "Q8INB9-1", "Q8IMC6-1", "Q8IR79-1", "Q9V3D5-1", "Q7PLI7-1", "A1Z9X0-1", "P08181-1", "P11346-1", "O61661-1", "A1ZBH7-1", "Q9VM90-1", "P49762-1", "A0A0B4KHX7-1", "M9PI41-1", "Q9W002-1", "Q9VPC0-1", "Q9VXG8-1", "Q9W354-1", "A1Z7T0-1", "O61443-1", "O97143-1", "P05130-1", "P16911-1", "P49657-1", "Q9NI63-1", "Q9V3Q6-1", "Q9VA38-1", "Q9VK45-1", "Q9W0V1-4", "Q9VT57-1", "Q9VI13-1", "Q0KHQ5-1", "Q0KHV6-1", "Q9NBK5-1", "A4VCL2-2", "Q9VP22-1", "Q9W1B0-1", "Q9V3I5-1", "A8JR46-1", "A0A126GUV7-1", "X2JAG8-1", "A0A0B4KHT3-1", "A1ZBC4-1", "A0A4D6K823-1", "A1ZBL9-1", "Q9VBU2-1", "Q9VL34-1", "M9PGC5-1", "Q9VUV4-1", "A0A6M3Q7C8-1", "Q9VE06-1", "Q9VMY8-1", "Q9VUQ9-1", "Q9VR61-1", "Q9VRJ6-1", "Q9VW24-1", "Q9VTL5-1", "Q9VJ30-1", "M9MS50-1", "Q94533-1", "Q9VGF9-1", "Q9VXN5-1", "Q9VD82-1", "Q24216-1", "Q9VR42-1", "Q9VI84-1", "A0A0B4KHL4-1", "A0A6M3Q6U2-1", "M9PE01-1", "B7Z126-1", "Q9VMN3-1", "Q9VEN3-1", "O18645-1", "Q9W3N8-1", "Q9VGI4-1", "Q9VHF6-1", "Q24171-1", "Q9VL64-1", "Q9VJ90-1", "Q9W532-1", "Q9VGP9-1", "Q9VGQ0-1", "Q9VPW3-1", "A4V2C3-1", "Q9W3Y1-1", "Q0E981-1", "Q9VXE3-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O61267-1", "P13677-1", "P23573-1", "P51123-1", "Q00168-1", "Q23977-1", "Q24210-3", "Q9VKN7-1", "O62618-1", "P10676-1", "P18431-2", "P23647-1", "P52304-1", "P83104-1", "Q03042-1", "Q70PP2-1", "Q8T0S6-1", "O76324-1", "P13678-1", "P16912-1", "P23572-1", "P40417-3", "P48609-1", "P49071-1", "P54367-1", "P83099-1", "P83100-1", "P83102-1", "P92208-1", "Q03043-1", "Q0KHT7-1", 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"A0A6M3Q6U2-1", "M9PE01-1", "B7Z126-1", "Q9VMN3-1", "Q9VEN3-1", "O18645-1", "Q9W3N8-1", "Q9VGI4-1", "Q9VHF6-1", "Q24171-1", "Q9VL64-1", "Q9VJ90-1", "Q9W532-1", "Q9VGP9-1", "Q9VGQ0-1", "Q9VPW3-1", "A4V2C3-1", "Q9W3Y1-1", "Q0E981-1", "Q9VXE3-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A0B4KHC3", "gene_name": "PKD", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A0B4KHC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHC3" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A0B4KHC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHC3" } ] }, { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A0B4KHC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHC3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A0B4KHC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHC3" } ] } ] }, { "uniprot_ac": "A0A0B4KHL4", "gene_name": "gish", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A0B4KHL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHL4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0B4KHL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHL4" } ] } ] }, { "uniprot_ac": "A0A0B4KHT3", "gene_name": "Lrrk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A0B4KHT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0B4KHT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHT3" } ] } ] }, { "uniprot_ac": "A0A0B4KHX7", "gene_name": "Gcn2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A0B4KHX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHX7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0B4KHX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHX7" } ] } ] }, { "uniprot_ac": "A0A126GUV7", "gene_name": "fray", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A126GUV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A126GUV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A126GUV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A126GUV7" } ] } ] }, { "uniprot_ac": "A0A4D6K823", "gene_name": "nmo", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A4D6K823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K823" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A4D6K823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A4D6K823" } ] } ] }, { "uniprot_ac": "A0A6M3Q6U2", "gene_name": "Hipk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A6M3Q6U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A6M3Q6U2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A6M3Q6U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A6M3Q6U2" } ] } ] }, { "uniprot_ac": "A0A6M3Q7C8", "gene_name": "SRPK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A6M3Q7C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A6M3Q7C8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A6M3Q7C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A6M3Q7C8" } ] } ] }, { "uniprot_ac": "A1Z7T0", "gene_name": "Pkn", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1Z7T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1Z7T0" } ] }, { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1Z7T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1Z7T0" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1Z7T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1Z7T0" } ] } ] }, { "uniprot_ac": "A1Z9X0", "gene_name": "aPKC", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1Z9X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1Z9X0" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A1Z9X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1Z9X0" } ] } ] }, { "uniprot_ac": "A1ZBC4", "gene_name": "Sik3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1ZBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1ZBC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A1ZBC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1ZBC4" } ] } ] }, { "uniprot_ac": "A1ZBH7", "gene_name": "hppy", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1ZBH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1ZBH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A1ZBH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1ZBH7" } ] } ] }, { "uniprot_ac": "A1ZBL9", "gene_name": "par-1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1ZBL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1ZBL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A1ZBL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1ZBL9" } ] } ] }, { "uniprot_ac": "A4V2C3", "gene_name": "Dmel\\CG17698", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A4V2C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4V2C3" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A4V2C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4V2C3" } ] } ] }, { "uniprot_ac": "A4VCL2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A4VCL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4VCL2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A4VCL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4VCL2" } ] } ] }, { "uniprot_ac": "A8JR46", "gene_name": "Ire1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A8JR46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8JR46" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A8JR46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8JR46" } ] } ] }, { "uniprot_ac": "B7Z126", "gene_name": "Tlk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "B7Z126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B7Z126" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "B7Z126", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B7Z126" } ] } ] }, { "uniprot_ac": "M9MS50", "gene_name": "Srpk79D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "M9MS50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9MS50" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "M9MS50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9MS50" } ] } ] }, { "uniprot_ac": "M9PE01", "gene_name": "Eip63E", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "M9PE01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9PE01" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "M9PE01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9PE01" } ] } ] }, { "uniprot_ac": "M9PGC5", "gene_name": "Wnk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "M9PGC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9PGC5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "M9PGC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9PGC5" } ] } ] }, { "uniprot_ac": "M9PI41", "gene_name": "sti", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "M9PI41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9PI41" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "M9PI41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9PI41" } ] } ] }, { "uniprot_ac": "O18645", "gene_name": "AMPKalpha", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "O18645", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O18645" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O18645", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O18645" } ] } ] }, { "uniprot_ac": "O61267", "gene_name": "lok", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "O61267", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O61267" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O61267", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O61267" } ] } ] }, { "uniprot_ac": "O61443", "gene_name": "p38b", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "O61443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O61443" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "O61443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O61443" } ] } ] }, { "uniprot_ac": "O61661", "gene_name": "grp", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "O61661", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O61661" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O61661", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O61661" } ] } ] }, { "uniprot_ac": "O62618", "gene_name": "p38a", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "O62618", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O62618" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "O62618", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O62618" } ] } ] }, { "uniprot_ac": "O76324", "gene_name": "dco", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "O76324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O76324" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "O76324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O76324" } ] } ] }, { "uniprot_ac": "O97143", "gene_name": "SAK", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "O97143", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O97143" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "O97143", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O97143" } ] } ] }, { "uniprot_ac": "P05130", "gene_name": "Pkc53E", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05130", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05130" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P05130", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05130" } ] } ] }, { "uniprot_ac": "P08181", "gene_name": "CkIIalpha", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P08181", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08181" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P08181", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08181" } ] } ] }, { "uniprot_ac": "P10676", "gene_name": "ninaC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P10676", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10676" } ] }, { "ec_number": "5.6.1.8", "activity": "ATP + H2O + myosin bound to actin filament at position(n) = ADP + phosphate + myosin bound to actin filament at position(n+1).", "evidence": [ { "id": "P10676", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10676" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P10676", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10676" } ] } ] }, { "uniprot_ac": "P11346", "gene_name": "Raf", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P11346", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11346" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P11346", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11346" } ] } ] }, { "uniprot_ac": "P12370", "gene_name": "Pka-C1", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P12370", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P12370" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P12370", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P12370" } ] } ] }, { "uniprot_ac": "P13677", "gene_name": "inaC", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13677", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13677" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P13677", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13677" } ] } ] }, { "uniprot_ac": "P13678", "gene_name": "Pkc98E", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13678", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13678" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P13678", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13678" } ] } ] }, { "uniprot_ac": "P16911", "gene_name": "Pka-C2", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P16911", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P16911" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P16911", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P16911" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P16911", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P16911" } ] } ] }, { "uniprot_ac": "P16912", "gene_name": "Pka-C3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P16912", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P16912" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P16912", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P16912" } ] } ] }, { "uniprot_ac": "P18431", "gene_name": "sgg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18431", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18431" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P18431", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18431" } ] } ] }, { "uniprot_ac": "P23572", "gene_name": "Cdk1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P23572", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P23572" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P23572", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P23572" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P23572", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P23572" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P23572", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P23572" } ] } ] }, { "uniprot_ac": "P23573", "gene_name": "Cdk2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P23573", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P23573" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P23573", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P23573" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P23573", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P23573" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P23573", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P23573" } ] } ] }, { "uniprot_ac": "P23647", "gene_name": "fu", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P23647", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P23647" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P23647", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P23647" } ] } ] }, { "uniprot_ac": "P40417", "gene_name": "rl", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P40417", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P40417" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P40417", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P40417" } ] } ] }, { "uniprot_ac": "P48609", "gene_name": "Cdk5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P48609", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48609" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P48609", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48609" } ] } ] }, { "uniprot_ac": "P49071", "gene_name": "MAPk-Ak2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P49071", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P49071" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P49071", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P49071" } ] } ] }, { "uniprot_ac": "P49657", "gene_name": "mnb", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P49657", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P49657" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "P49657", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P49657" } ] } ] }, { "uniprot_ac": "P49762", "gene_name": "Doa", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P49762", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P49762" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "P49762", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P49762" } ] } ] }, { "uniprot_ac": "P51123", "gene_name": "Taf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P51123", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P51123" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P51123", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P51123" } ] } ] }, { "uniprot_ac": "P52304", "gene_name": "polo", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P52304", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52304" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "P52304", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52304" } ] } ] }, { "uniprot_ac": "P54360", "gene_name": "fj", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P54360", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P54360" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P54360", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P54360" } ] } ] }, { "uniprot_ac": "P54367", "gene_name": "CkIalpha", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P54367", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P54367" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P54367", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P54367" } ] } ] }, { "uniprot_ac": "P83099", "gene_name": "Pkcdelta", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P83099", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P83099" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P83099", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P83099" } ] } ] }, { "uniprot_ac": "P83100", "gene_name": "p38c", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P83100", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P83100" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P83100", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P83100" } ] } ] }, { "uniprot_ac": "P83102", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P83102", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P83102" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "P83102", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P83102" } ] } ] }, { "uniprot_ac": "P83103", "gene_name": "Haspin", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P83103", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P83103" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P83103", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P83103" } ] } ] }, { "uniprot_ac": "P83104", "gene_name": "Takl1", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P83104", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P83104" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "P83104", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P83104" } ] } ] }, { "uniprot_ac": "P92208", "gene_name": "bsk", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P92208", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P92208" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P92208", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P92208" } ] } ] }, { "uniprot_ac": "Q00168", "gene_name": "CaMKII", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q00168", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q00168" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q00168", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q00168" } ] } ] }, { "uniprot_ac": "Q03042", "gene_name": "Pkg21D", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q03042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q03042" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "Q03042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q03042" } ] } ] }, { "uniprot_ac": "Q03043", "gene_name": "for", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q03043", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q03043" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "Q03043", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q03043" } ] } ] }, { "uniprot_ac": "Q05652", "gene_name": "pll", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q05652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05652" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q05652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05652" } ] } ] }, { "uniprot_ac": "Q0E981", "gene_name": "Snrk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0E981", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0E981" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0E981", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0E981" } ] } ] }, { "uniprot_ac": "Q0KHQ5", "gene_name": "Tao", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0KHQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0KHQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0KHQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0KHQ5" } ] } ] }, { "uniprot_ac": "Q0KHT7", "gene_name": "Drak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0KHT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0KHT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0KHT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0KHT7" } ] } ] }, { "uniprot_ac": "Q0KHV6", "gene_name": "Pink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0KHV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0KHV6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0KHV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0KHV6" } ] } ] }, { "uniprot_ac": "Q23977", "gene_name": "hep", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q23977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q23977" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q23977", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q23977" } ] } ] }, { "uniprot_ac": "Q24171", "gene_name": "ksr", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q24171", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q24171" } ] } ] }, { "uniprot_ac": "Q24210", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q24210", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q24210" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "Q24210", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q24210" } ] } ] }, { "uniprot_ac": "Q24216", "gene_name": "Cdk7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q24216", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q24216" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "Q24216", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q24216" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q24216", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q24216" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q24216", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q24216" } ] } ] }, { "uniprot_ac": "Q24324", "gene_name": "Dsor1", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q24324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q24324" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q24324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q24324" } ] } ] }, { "uniprot_ac": "Q5EAK6", "gene_name": "tefu", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5EAK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAK6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5EAK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5EAK6" } ] } ] }, { "uniprot_ac": "Q70PP2", "gene_name": "nonC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q70PP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q70PP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q70PP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q70PP2" } ] } ] }, { "uniprot_ac": "Q7KRY6", "gene_name": "ball", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q7KRY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7KRY6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7KRY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7KRY6" } ] } ] }, { "uniprot_ac": "Q7PLI7", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q7PLI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7PLI7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7PLI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7PLI7" } ] } ] }, { "uniprot_ac": "Q8IMC6", "gene_name": "Asator", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8IMC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8IMC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8IMC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8IMC6" } ] } ] }, { "uniprot_ac": "Q8INB9", "gene_name": "Akt", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8INB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8INB9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8INB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8INB9" } ] } ] }, { "uniprot_ac": "Q8IR79", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8IR79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8IR79" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8IR79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8IR79" } ] } ] }, { "uniprot_ac": "Q8T0S6", "gene_name": "hpo", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8T0S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8T0S6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8T0S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8T0S6" } ] } ] }, { "uniprot_ac": "Q94533", "gene_name": "S6k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q94533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q94533" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q94533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q94533" } ] } ] }, { "uniprot_ac": "Q95UN8", "gene_name": "slpr", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q95UN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95UN8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q95UN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95UN8" } ] } ] }, { "uniprot_ac": "Q9I7F7", "gene_name": "Ack-like", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9I7F7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9I7F7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q9I7F7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9I7F7" } ] } ] }, { "uniprot_ac": "Q9NBK5", "gene_name": "trc", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9NBK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9NBK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9NBK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9NBK5" } ] } ] }, { "uniprot_ac": "Q9NI63", "gene_name": "Myt1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9NI63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9NI63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9NI63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9NI63" } ] } ] }, { "uniprot_ac": "Q9NIV1", "gene_name": "PEK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9NIV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9NIV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9NIV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9NIV1" } ] } ] }, { "uniprot_ac": "Q9V3D5", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9V3D5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9V3D5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q9V3D5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9V3D5" } ] } ] }, { "uniprot_ac": "Q9V3I5", "gene_name": "JIL-1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9V3I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9V3I5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9V3I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9V3I5" } ] } ] }, { "uniprot_ac": "Q9V3Q6", "gene_name": "Tak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9V3Q6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9V3Q6" } ] }, { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9V3Q6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9V3Q6" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "Q9V3Q6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9V3Q6" } ] } ] }, { "uniprot_ac": "Q9VA38", "gene_name": "wts", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9VA38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VA38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VA38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VA38" } ] } ] }, { "uniprot_ac": "Q9VBU2", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9VBU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VBU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VBU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VBU2" } ] } ] }, { "uniprot_ac": "Q9VD82", "gene_name": "Dmel\\CG6800", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9VD82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VD82" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q9VD82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VD82" } ] } ] }, { "uniprot_ac": "Q9VE06", "gene_name": "cdi", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9VE06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VE06" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q9VE06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VE06" } ] } ] }, { "uniprot_ac": "Q9VEN3", "gene_name": "GckIII", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9VEN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VEN3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VEN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VEN3" } ] } ] }, { "uniprot_ac": "Q9VGF9", "gene_name": "aurA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9VGF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VGF9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VGF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VGF9" } ] } ] }, { "uniprot_ac": "Q9VGI4", "gene_name": "Lk6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9VGI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VGI4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VGI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VGI4" } ] } ] }, { "uniprot_ac": "Q9VGP9", "gene_name": "KP78a", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9VGP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VGP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VGP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VGP9" } ] } ] }, { "uniprot_ac": "Q9VGQ0", "gene_name": "KP78b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9VGQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VGQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VGQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VGQ0" } ] } ] }, { "uniprot_ac": "Q9VHF6", "gene_name": "Aduk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9VHF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VHF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VHF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VHF6" } ] } ] }, { "uniprot_ac": "Q9VI13", "gene_name": "Pak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9VI13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VI13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VI13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VI13" } ] } ] }, { "uniprot_ac": "Q9VI84", "gene_name": "Dmel\\CG1227", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9VI84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VI84" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VI84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VI84" } ] } ] }, { "uniprot_ac": "Q9VJ30", "gene_name": "Nak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9VJ30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJ30" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VJ30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJ30" } ] } ] }, { "uniprot_ac": "Q9VJ90", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9VJ90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJ90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VJ90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJ90" } ] } ] }, { "uniprot_ac": "Q9VK45", "gene_name": "mTor", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9VK45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VK45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VK45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VK45" } ] } ] }, { "uniprot_ac": "Q9VKN7", "gene_name": "aurB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9VKN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VKN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VKN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VKN7" } ] } ] }, { 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Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUS9", "url": "https://www.uniprot.org/uniprotkb/Q9VUS9" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUS9", "url": "https://www.uniprot.org/uniprotkb/Q9VUS9" } ], "reference": [ { "type": 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Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW0", "url": "https://www.uniprot.org/uniprotkb/Q9VUW0" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW0", "url": "https://www.uniprot.org/uniprotkb/Q9VUW0" } ], "reference": [ { "type": "PubMed", 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"https://www.alliancegenome.org/disease/DOID:5419" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VUW1", "url": "https://www.uniprot.org/uniprotkb/Q9VUW1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "cg17026", "url": "https://www.uniprot.org/uniprotkb/Q9VUW1", "locus": { "chromosome": "3L", "start_pos": 15976428, "end_pos": 15975368, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0036550", "url": "https://www.ensemblgenomes.org/id/FBgn0036550" } ] } } ], "crossref": [ { "id": "FB:FBgn0036550", "url": "https://alliancegenome.org/gene/FB:FBgn0036550", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0036550", "url": "https://bgee.org/?page=gene&gene_id=FBgn0036550", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01639", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01639", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0036550", "url": "https://flybase.org/reports/FBgn0036550", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "39739", "url": "https://www.ncbi.nlm.nih.gov/gene/39739", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VUW1", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VUW1*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR000760", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000760", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020550", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020550", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020552", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020552", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020583", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020583", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033942", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033942", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG17026", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG17026", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SYPEHKF", "url": "https://omabrowser.org/oma/group/SYPEHKF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VUW1", "url": "https://www.orthodb.org/?gene=Q9VUW1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20854", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20854", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20854:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20854:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00459", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00459", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-1855183", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1855183", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_648820", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648820", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "24056", "url": "https://www.rhea-db.org/rhea/24056", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q9VUW1", "url": "https://www.uniprot.org/uniprotkb/Q9VUW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VUW1-1", "url": "https://www.uniprot.org/uniprotkb/Q9VUW1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAASKSQIEELYDFIYPLAVRAGEILLEGYQNAGKAVALKDGEFYNVVTAYDNQIEEFLVEKILARYPDHKFIGEEDTHKNDNVTKELTDAPTWIIDPIDGTSNFIKQIPHVSVSIGLSIKKQIVLGVVNNPAQNKLYTAKLGQGAFCNGKPIQVSSCEHLNDANVAYEVCLLHAPKIRNKHIKRIYHVGSNARRLLAYSAVVDSLCMVAAGNLDAFHIEDMYPWDCAAGYLLIREAGGVVTHPYGGPFDIMKPDLICAGTETLRAEIEHLIRKADQEKHVGGE", "length": 284, "header": "tr|Q9VUW1-1|Q9VUW1_DROME Isoform 1 of Inositol-1-monophosphatase OS=Drosophila melanogaster OX=7227 GN=cg17026 PE=3 SV=1 CANONICAL=Q9VUW1-1" }, "isoforms": [ { "isoform_ac": "Q9VUW1-1", "url": "https://www.uniprot.org/uniprotkb/Q9VUW1/entry#Q9VUW1-1", "sequence": { "sequence": "MAASKSQIEELYDFIYPLAVRAGEILLEGYQNAGKAVALKDGEFYNVVTAYDNQIEEFLVEKILARYPDHKFIGEEDTHKNDNVTKELTDAPTWIIDPIDGTSNFIKQIPHVSVSIGLSIKKQIVLGVVNNPAQNKLYTAKLGQGAFCNGKPIQVSSCEHLNDANVAYEVCLLHAPKIRNKHIKRIYHVGSNARRLLAYSAVVDSLCMVAAGNLDAFHIEDMYPWDCAAGYLLIREAGGVVTHPYGGPFDIMKPDLICAGTETLRAEIEHLIRKADQEKHVGGE", "length": 284, "header": "tr|Q9VUW1-1|Q9VUW1_DROME Isoform 1 of Inositol-1-monophosphatase OS=Drosophila melanogaster OX=7227 GN=cg17026 PE=3 SV=1 CANONICAL=Q9VUW1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW1", "url": "https://www.uniprot.org/uniprotkb/Q9VUW1" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW1", "url": "https://www.uniprot.org/uniprotkb/Q9VUW1" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW1", "url": "https://www.uniprot.org/uniprotkb/Q9VUW1" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW1", "url": "https://www.uniprot.org/uniprotkb/Q9VUW1" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW1", "url": "https://www.uniprot.org/uniprotkb/Q9VUW1" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW1", "url": "https://www.uniprot.org/uniprotkb/Q9VUW1" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW1", "url": "https://www.uniprot.org/uniprotkb/Q9VUW1" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW1", "url": "https://www.uniprot.org/uniprotkb/Q9VUW1" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW1", "url": "https://www.uniprot.org/uniprotkb/Q9VUW1" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW1", "url": "https://www.uniprot.org/uniprotkb/Q9VUW1" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW1", "url": "https://www.uniprot.org/uniprotkb/Q9VUW1" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG17026", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG17026", "resource": "KEGG Pathway" }, { "id": "R-DME-1855183", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1855183", "resource": "Reactome", "description": "Synthesis of IP2, IP, and Ins in the cytosol" } ], "orthologs": [ { "uniprot_canonical_ac": "O14732-1", "protein_name": "Inositol monophosphatase 2", "gene_name": "IMPA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKPSGEDQAALAAGPWEECFQAAVQLALRAGQIIRKALTEEKRVSTKTSAADLVTETDHLVEDLIISELRERFPSHRFIAEEAAASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGVIYHCTEERLYTGRRGRGAFCNGQRLRVSGETDLSKALVLTEIGPKRDPATLKLFLSNMERLLHAKAHGVRVIGSSTLALCHLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSGGPLDLMACRVVAASTREMAMLIAQALQTINYGRDDEK", "length": 288 }, "evidence": [ { "id": "MGI:2149728", "url": "https://alliancegenome.org/gene/MGI:2149728#orthology", "database": "AGR" }, { "id": "HGNC:6051", "url": "https://alliancegenome.org/gene/HGNC:6051#orthology", "database": "AGR" }, { "id": "RGD:628692", "url": "https://alliancegenome.org/gene/RGD:628692#orthology", "database": "AGR" }, { "id": "FB:FBgn0036550", "url": "https://alliancegenome.org/gene/FB:FBgn0036550#orthology", "database": "AGR" }, { "id": "SGD:S000001088", "url": "https://alliancegenome.org/gene/SGD:S000001088#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O55023-1", "protein_name": "Inositol monophosphatase 1", "gene_name": "Impa1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADPWQECMDYAVILARQAGEMIREALKNEMDVMIKSSPADLVTVTDQKVEKMLMSSIKEKYPCHSFIGEESVAAGEKTVFTESPTWFIDPIDGTTNFVHRFPFVAVSIGFLVNKEMEFGIVYSCVEDKMYTGRKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRKPETLRIVLSNMEKLCSIPIHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDMAGAGIIVTEAGGVLMDVTGGPFDLMSRRIIAANSITLAKRIAKEIEIIPLQRDDES", "length": 277 }, "evidence": [ { "id": "MGI:1933158", "url": "https://alliancegenome.org/gene/MGI:1933158#orthology", "database": "AGR" }, { "id": "HGNC:6050", "url": "https://alliancegenome.org/gene/HGNC:6050#orthology", "database": "AGR" }, { "id": "RGD:69254", "url": "https://alliancegenome.org/gene/RGD:69254#orthology", "database": "AGR" }, { "id": "FB:FBgn0036550", "url": "https://alliancegenome.org/gene/FB:FBgn0036550#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P29218-1", "protein_name": "Inositol monophosphatase 1", "gene_name": "IMPA1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADPWQECMDYAVTLARQAGEVVCEAIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKEKYPSHSFIGEESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVVYSCVEGKMYTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNMEKLFCIPVHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVTGGPFDLMSRRVIAANNRILAERIAKEIQVIPLQRDDED", "length": 277 }, "evidence": [ { "id": "MGI:1933158", "url": "https://alliancegenome.org/gene/MGI:1933158#orthology", "database": "AGR" }, { "id": "HGNC:6050", "url": "https://alliancegenome.org/gene/HGNC:6050#orthology", "database": "AGR" }, { "id": "RGD:69254", "url": "https://alliancegenome.org/gene/RGD:69254#orthology", "database": "AGR" }, { "id": "FB:FBgn0036550", "url": "https://alliancegenome.org/gene/FB:FBgn0036550#orthology", "database": "AGR" }, { "id": "SGD:S000001088", "url": "https://alliancegenome.org/gene/SGD:S000001088#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P38710-1", "protein_name": "Inositol monophosphatase 1", "gene_name": "INM1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTIDLASIEKFLCELATEKVGPIIKSKSGTQKDYDLKTGSRSVDIVTAIDKQVEKLIWESVKTQYPTFKFIGEESYVKGETVITDDPTFIIDPIDGTTNFVHDFPFSCTSLGLTVNKEPVVGVIYNPHINLLVSASKGNGMRVNNKDYDYKSKLESMGSLILNKSVVALQPGSAREGKNFQTKMATYEKLLSCDYGFVHGFRNLGSSAMTMAYIAMGYLDSYWDGGCYSWDVCAGWCILKEVGGRVVGANPGEWSIDVDNRTYLAVRGTINNESDEQTKYITDFWNCVDGHLKYD", "length": 295 }, "evidence": [ { "id": "MGI:2149728", "url": "https://alliancegenome.org/gene/MGI:2149728#orthology", "database": "AGR" }, { "id": "HGNC:6050", "url": "https://alliancegenome.org/gene/HGNC:6050#orthology", "database": "AGR" }, { "id": "HGNC:6051", "url": "https://alliancegenome.org/gene/HGNC:6051#orthology", "database": "AGR" }, { "id": "RGD:628692", "url": "https://alliancegenome.org/gene/RGD:628692#orthology", "database": "AGR" }, { "id": "FB:FBgn0036550", "url": "https://alliancegenome.org/gene/FB:FBgn0036550#orthology", "database": "AGR" }, { "id": "SGD:S000001088", "url": "https://alliancegenome.org/gene/SGD:S000001088#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P97697-1", "protein_name": "Inositol monophosphatase 1", "gene_name": "Impa1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADPWQECMDYAVILARQAGEMIREALKNKMDVMIKSSPADLVTVTDQKVEKMLMSSIKEKYPYHSFIGEESVASGEKTVFTEQPTWIIDPIDGTTNFVHRFPFVAVSIGFVVNKEMEFGVVYSCVEDKMYTGRKGKGAFCNGQKLRVSQQEDITKSLLVTELGSSRKPETLRIVLSNMERLCSIPIHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDMAGAGIIVIEAGGVLLDVTGGPFDLMSRRIIAASNIALAERIAKELEIIPLQRDDES", "length": 277 }, "evidence": [ { "id": "MGI:1933158", "url": "https://alliancegenome.org/gene/MGI:1933158#orthology", "database": "AGR" }, { "id": "HGNC:6050", "url": "https://alliancegenome.org/gene/HGNC:6050#orthology", "database": "AGR" }, { "id": "RGD:69254", "url": "https://alliancegenome.org/gene/RGD:69254#orthology", "database": "AGR" }, { "id": "FB:FBgn0036550", "url": "https://alliancegenome.org/gene/FB:FBgn0036550#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q05533-1", "protein_name": "Inositol monophosphatase 2", "gene_name": "INM2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVLTRQVLEEVENTFIELLRSKIGPLVKSHAGTNFCSYDDKANGVDLVTALDKQIESIIKENLTAKYPSFKFIGEETYVKGVTKITNGPTFIVDPIDGTTNFIHGYPYSCTSLGLAEMGKPVVGVVFNPHLNQLFHASKGNGAFLNDQEIKVSKRPLILQKSLIALEGGSERTEGSQGNFDKKMNTYKNLLSESGAFVHGFRSAGSAAMNICYVASGMLDAYWEGGCWAWDVCAGWCILEEAGGIMVGGNCGEWNIPLDRRCYLAIRGGCESMEQKRFAESFWPHVAGELEY", "length": 292 }, "evidence": [ { "id": "MGI:1933158", "url": "https://alliancegenome.org/gene/MGI:1933158#orthology", "database": "AGR" }, { "id": "MGI:2149728", "url": "https://alliancegenome.org/gene/MGI:2149728#orthology", "database": "AGR" }, { "id": "HGNC:6050", "url": "https://alliancegenome.org/gene/HGNC:6050#orthology", "database": "AGR" }, { "id": "HGNC:6051", "url": "https://alliancegenome.org/gene/HGNC:6051#orthology", "database": "AGR" }, { "id": "RGD:628692", "url": "https://alliancegenome.org/gene/RGD:628692#orthology", "database": "AGR" }, { "id": "RGD:69254", "url": "https://alliancegenome.org/gene/RGD:69254#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q7KTW5-1", "protein_name": "Inositol-1-monophosphatase", "gene_name": "Dmel\\CG9391", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSHNVDVEKCLEVASNLVSEAGRLIARNNEQRQDFVCKSNDIDLVTQTDKDVEQLLMDGIRRHFPEHKFIGEEESSGAEGVKKLTDEPTWIIDPVDGTMNFVHAFPHSCISVGLKVNKVTELGLVYNPILEQRFTARRGHGAFYNGRRIHVSGQKELGKALVTSEFGTTRDEAKMKVVHENFEKMAKKAHGLRVLGSAALNMSMVALGAADANYEFGIHAWDVCAGDLIVREAGGVVIDPAGGEFDIMSRRVLAAATPELAQEISKVLTQFNPLPRDD", "length": 278 }, "evidence": [ { "id": "MGI:1933158", "url": "https://alliancegenome.org/gene/MGI:1933158#orthology", "database": "AGR" }, { "id": "MGI:2149728", "url": "https://alliancegenome.org/gene/MGI:2149728#orthology", "database": "AGR" }, { "id": "HGNC:6050", "url": "https://alliancegenome.org/gene/HGNC:6050#orthology", "database": "AGR" }, { "id": "HGNC:6051", "url": "https://alliancegenome.org/gene/HGNC:6051#orthology", "database": "AGR" }, { "id": "RGD:628692", "url": "https://alliancegenome.org/gene/RGD:628692#orthology", "database": "AGR" }, { "id": "RGD:69254", "url": "https://alliancegenome.org/gene/RGD:69254#orthology", "database": "AGR" }, { "id": "SGD:S000001088", "url": "https://alliancegenome.org/gene/SGD:S000001088#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8CIN7-1", "protein_name": "Inositol monophosphatase 2", "gene_name": "Impa2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKPNSEEEEELVQGVGPWDECFEVAVQLALRAGQIIRKALTEEKHVSTKTSAADLVTETDHRVEDLIVSELRKRFPSHRFIAEEATASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVHQELEFGVIHHCTEERLYTGRRGQGAFCNGQRLQVSRETDLAKALVLTEIGPKRDPDTLKVFLSNMERLLHAKAHGVRVIGSSTLALCYLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSGGPLDLMSCRVVAAGTREMAVLIAQALQTINYGRDDEK", "length": 290 }, "evidence": [ { "id": "MGI:2149728", "url": "https://alliancegenome.org/gene/MGI:2149728#orthology", "database": "AGR" }, { "id": "HGNC:6051", "url": "https://alliancegenome.org/gene/HGNC:6051#orthology", "database": "AGR" }, { "id": "RGD:628692", "url": "https://alliancegenome.org/gene/RGD:628692#orthology", "database": "AGR" }, { "id": "FB:FBgn0036550", "url": "https://alliancegenome.org/gene/FB:FBgn0036550#orthology", "database": "AGR" }, { "id": "SGD:S000001088", "url": "https://alliancegenome.org/gene/SGD:S000001088#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q91UZ5-1", "protein_name": "Inositol monophosphatase 2", "gene_name": "Impa2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKPSSEEEGELVQGVGPWDECFEVAVQLALRAGQIIRKALTEEKRVSTKTSAADLVTETDHRVEDLIVSELRKRFPSHRFIAEEATASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVHQELEFGVIHHCTEERLYTGRRGQGAFCNGQRLQVSRETDLAKALVLTEIGPKRDPDTLKVFLSNMERLLHAKAHGVRVIGSSTLALCYLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSGGPLDLMSCRVVAAGTREMAVLIAQALQTINYGRDDEK", "length": 290 }, "evidence": [ { "id": "MGI:2149728", "url": "https://alliancegenome.org/gene/MGI:2149728#orthology", "database": "AGR" }, { "id": "HGNC:6051", "url": "https://alliancegenome.org/gene/HGNC:6051#orthology", "database": "AGR" }, { "id": "RGD:628692", "url": "https://alliancegenome.org/gene/RGD:628692#orthology", "database": "AGR" }, { "id": "FB:FBgn0036550", "url": "https://alliancegenome.org/gene/FB:FBgn0036550#orthology", "database": "AGR" }, { "id": "SGD:S000001088", "url": "https://alliancegenome.org/gene/SGD:S000001088#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VP62-1", "protein_name": "inositol-phosphate phosphatase", "gene_name": "Dmel\\CG9389", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVDEKLPPSKEPAERPPDQTTPGNAATRFGLEDHEATQQDARVNTLRQAEERRGSMVPPDKRAMSMKMSQARLHTINDPNRTGTHSAEATTPPAKPAVNISSRSSLVRGVAPDLPPKPQRPSDSEADLESSDVDRPSAKRKSEKALADVSTSSSEESEKRVPPAAASAPPPAQAEPQWKSIDFAASEAEPIAPPAPRPEDVPLPPPMMSSLPTDGSPDDVQSINSKLTNTDITFHPSKVFASKATNTSGMLYSDEENEPEEEEFPKLPDQFSASDLDTLFLLACREVKKAGAIALAENKKNQEYTTKKHTNDIVTPTDNIVEESFIKAISSRYPNHQFIAEERISKSETGMVTLTDDPTWIIDPIDGTMNFVHHFPYYCISVAYLVNQETQFGIIYNPPMKNMYTAQLGKGAQMNGEMIRTTGQTNLSAAMVLQEYSSGSNEARNQVATENSQRLVKKTHAMRSIGSSAMCLAMVASGVADAFYNFGLHVWDMAAGALIVTEAGGVVMDPAGEELDIMSRRCLAASTDYLALELGNCLQQNYPSPRDDEPRSVNPNEYGPAPETRDFTSQTDFPDSDTPETTDTEIGGEKSATPAN", "length": 596 }, "evidence": [ { "id": "MGI:2149728", "url": "https://alliancegenome.org/gene/MGI:2149728#orthology", "database": "AGR" }, { "id": "HGNC:6051", "url": "https://alliancegenome.org/gene/HGNC:6051#orthology", "database": "AGR" }, { "id": "RGD:628692", "url": "https://alliancegenome.org/gene/RGD:628692#orthology", "database": "AGR" }, { "id": "SGD:S000001088", "url": "https://alliancegenome.org/gene/SGD:S000001088#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VUW2-1", "protein_name": "Inositol-1-monophosphatase", "gene_name": "IMP", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSSAVSESKLKEYYDVALKLVLKCGPLMQEGYQKAKTEYKVKADFYDLVTVYDKQIEDILTEGLVAAFPESLIIGEEESAVSQRQAELTDAPTWIIDPIDGTTNFIHRIPHCCISVGLAINKELVVGIIYNPPANELFSAYKGHGAYLNGEPIHTSKVTTIKQAVIAYEISLIHAAGVRDKNVKRLYKMASNATGTRCFGSAALTLCYVATGQCDAYHVEDLKPWDIAAGAIILTEAGGTVCHTSGSKFDVMKPDCVCAATPELAKNVISLIEEAGQITEYTFK", "length": 284 }, "evidence": [ { "id": "MGI:1933158", "url": "https://alliancegenome.org/gene/MGI:1933158#orthology", "database": "AGR" }, { "id": "MGI:2149728", "url": "https://alliancegenome.org/gene/MGI:2149728#orthology", "database": "AGR" }, { "id": "HGNC:6050", "url": "https://alliancegenome.org/gene/HGNC:6050#orthology", "database": "AGR" }, { "id": "HGNC:6051", "url": "https://alliancegenome.org/gene/HGNC:6051#orthology", "database": "AGR" }, { "id": "RGD:628692", "url": "https://alliancegenome.org/gene/RGD:628692#orthology", "database": "AGR" }, { "id": "RGD:69254", "url": "https://alliancegenome.org/gene/RGD:69254#orthology", "database": "AGR" }, { "id": "SGD:S000001088", "url": "https://alliancegenome.org/gene/SGD:S000001088#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VUW3-1", "protein_name": "Inositol-1-monophosphatase", "gene_name": "IMP", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSYRIGEEKLEVYYQVSLELVRKCGPLFLEGFQKPKTDYEVKSAFYDLVTVYDKQIEATLTDGLLKTFPESKIIGEEAMANAKTPPELTDAPTWIIDPIDGTNNYVRKIPHCCISVGLAINKELVLGIVYNPSANELYSAWQGHGAYLNGQPIEVSNAKKINQALVCYEISLIVVSKGRDKNVKRLYKLASSATGTRSFGCAALTLCYIAAGRCDAYHVENLKPWDLAGGAVILREAGGRVYHTSGARFDVMKPDCVCTSSEELAKSVIQLIEGADQISGYTFK", "length": 284 }, "evidence": [ { "id": "MGI:1933158", "url": "https://alliancegenome.org/gene/MGI:1933158#orthology", "database": "AGR" }, { "id": "MGI:2149728", "url": "https://alliancegenome.org/gene/MGI:2149728#orthology", "database": "AGR" }, { "id": "HGNC:6050", "url": "https://alliancegenome.org/gene/HGNC:6050#orthology", "database": "AGR" }, { "id": "HGNC:6051", "url": "https://alliancegenome.org/gene/HGNC:6051#orthology", "database": "AGR" }, { "id": "RGD:628692", "url": "https://alliancegenome.org/gene/RGD:628692#orthology", "database": "AGR" }, { "id": "RGD:69254", "url": "https://alliancegenome.org/gene/RGD:69254#orthology", "database": "AGR" }, { "id": "SGD:S000001088", "url": "https://alliancegenome.org/gene/SGD:S000001088#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VUW4-1", "protein_name": "Inositol-1-monophosphatase", "gene_name": "IMP", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAGVSQADIEELYNFIHPLAIKAGEILMEGYEMASKNVSIKGDFYDVVTDYDNKIEDFLMEKILARYPDHKFIGEEETAKNNNVSGELTNAPTWIIDPIDGTSNFIKQIPHVCVSIGLAINKQIVVGVINNPVQKKLFTTKLGQGAFCNGKPIHVSSCESVKDANVAYEVSLLHVHSVANKHIKRIYHVGLNARRLVAYSCVVDELCMVAAGNLDAFYIEDMYPWDCAAGSLLVKEAGGVVTHPFGGPFDIMKPDLICAGTEKLRKEIEDLLRKGDQEESVGGKPVQK", "length": 288 }, "evidence": [ { "id": "MGI:1933158", "url": "https://alliancegenome.org/gene/MGI:1933158#orthology", "database": "AGR" }, { "id": "MGI:2149728", "url": "https://alliancegenome.org/gene/MGI:2149728#orthology", "database": "AGR" }, { "id": "HGNC:6050", "url": "https://alliancegenome.org/gene/HGNC:6050#orthology", "database": "AGR" }, { "id": "HGNC:6051", "url": "https://alliancegenome.org/gene/HGNC:6051#orthology", "database": "AGR" }, { "id": "RGD:628692", "url": "https://alliancegenome.org/gene/RGD:628692#orthology", "database": "AGR" }, { "id": "RGD:69254", "url": "https://alliancegenome.org/gene/RGD:69254#orthology", "database": "AGR" }, { "id": "SGD:S000001088", "url": "https://alliancegenome.org/gene/SGD:S000001088#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "inositol metabolic process", "id": "GO:0006020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006020", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW1", "url": "https://www.uniprot.org/uniprotkb/Q9VUW1" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW1", "url": "https://www.uniprot.org/uniprotkb/Q9VUW1" } ], "pmid": "" }, { "name": "inositol biosynthetic process", "id": "GO:0006021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006021", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW1", "url": "https://www.uniprot.org/uniprotkb/Q9VUW1" } ], "pmid": "" }, { "name": "phosphatidylinositol phosphate biosynthetic process", "id": "GO:0046854", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046854", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW1", "url": "https://www.uniprot.org/uniprotkb/Q9VUW1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "inositol monophosphate phosphatase activity", "id": "GO:0052834", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052834", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW1", "url": "https://www.uniprot.org/uniprotkb/Q9VUW1" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW1", "url": "https://www.uniprot.org/uniprotkb/Q9VUW1" } ], "pmid": "" }, { "name": "inositol monophosphate 1-phosphatase activity", "id": "GO:0008934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008934", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW1", "url": "https://www.uniprot.org/uniprotkb/Q9VUW1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW1", "url": "https://www.uniprot.org/uniprotkb/Q9VUW1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 83, "end_pos": 85, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "24056", "name": "", "equation": "a myo-inositol phosphate + H2O = myo-inositol + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VYF2-1", "Q7KTW5-1", "Q9VP62-1", "Q9VUW1-1", "Q9VUW2-1", "Q9VUW4-1", "Q9VUW3-1" ], "evidence": [ { "id": "24056", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/24056" } ] }, { "id": "R-DME-1855154", "name": "I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-870330" ], "output_participant_list": [], "enzyme_list": [ "Q9VP62-1", "Q7KTW5-1", "Q9VUW3-1", "Q9VUW1-1", "Q9VUW2-1", "Q9VUW4-1" ], "evidence": [ { "id": "R-DME-1855154", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1855154" } ] }, { "id": "R-DME-1855210", "name": "I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-1629731" ], "output_participant_list": [], "enzyme_list": [ "Q9VP62-1", "Q7KTW5-1", "Q9VUW3-1", "Q9VUW1-1", "Q9VUW2-1", "Q9VUW4-1" ], "evidence": [ { "id": "R-DME-1855210", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1855210" } ] }, { "id": "R-DME-1855211", "name": "I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. 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"categories": [ "Gene Expression" ] }, { "id": "cd01639", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01639", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0036551", "url": "https://flybase.org/reports/FBgn0036551", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "39740", "url": "https://www.ncbi.nlm.nih.gov/gene/39740", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VUW2", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VUW2*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR000760", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000760", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020550", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020550", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020552", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020552", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020583", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020583", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033942", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033942", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG17029", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG17029", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FNVMKPD", "url": "https://omabrowser.org/oma/group/FNVMKPD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VUW2", "url": "https://www.orthodb.org/?gene=Q9VUW2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20854", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20854", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20854:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20854:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00459", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00459", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-1855183", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1855183", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001261908", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261908", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "24056", "url": "https://www.rhea-db.org/rhea/24056", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q9VUW2", "url": "https://www.uniprot.org/uniprotkb/Q9VUW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VUW2-1", "url": "https://www.uniprot.org/uniprotkb/Q9VUW2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSAVSESKLKEYYDVALKLVLKCGPLMQEGYQKAKTEYKVKADFYDLVTVYDKQIEDILTEGLVAAFPESLIIGEEESAVSQRQAELTDAPTWIIDPIDGTTNFIHRIPHCCISVGLAINKELVVGIIYNPPANELFSAYKGHGAYLNGEPIHTSKVTTIKQAVIAYEISLIHAAGVRDKNVKRLYKMASNATGTRCFGSAALTLCYVATGQCDAYHVEDLKPWDIAAGAIILTEAGGTVCHTSGSKFDVMKPDCVCAATPELAKNVISLIEEAGQITEYTFK", "length": 284, "header": "tr|Q9VUW2-1|Q9VUW2_DROME Isoform 1 of Inositol-1-monophosphatase OS=Drosophila melanogaster OX=7227 GN=IMP PE=1 SV=1 CANONICAL=Q9VUW2-1" }, "isoforms": [ { "isoform_ac": "Q9VUW2-1", "url": "https://www.uniprot.org/uniprotkb/Q9VUW2/entry#Q9VUW2-1", "sequence": { "sequence": "MSSAVSESKLKEYYDVALKLVLKCGPLMQEGYQKAKTEYKVKADFYDLVTVYDKQIEDILTEGLVAAFPESLIIGEEESAVSQRQAELTDAPTWIIDPIDGTTNFIHRIPHCCISVGLAINKELVVGIIYNPPANELFSAYKGHGAYLNGEPIHTSKVTTIKQAVIAYEISLIHAAGVRDKNVKRLYKMASNATGTRCFGSAALTLCYVATGQCDAYHVEDLKPWDIAAGAIILTEAGGTVCHTSGSKFDVMKPDCVCAATPELAKNVISLIEEAGQITEYTFK", "length": 284, "header": "tr|Q9VUW2-1|Q9VUW2_DROME Isoform 1 of Inositol-1-monophosphatase OS=Drosophila melanogaster OX=7227 GN=IMP PE=1 SV=1 CANONICAL=Q9VUW2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW2", "url": "https://www.uniprot.org/uniprotkb/Q9VUW2" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW2", "url": "https://www.uniprot.org/uniprotkb/Q9VUW2" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW2", "url": "https://www.uniprot.org/uniprotkb/Q9VUW2" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW2", "url": "https://www.uniprot.org/uniprotkb/Q9VUW2" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW2", "url": "https://www.uniprot.org/uniprotkb/Q9VUW2" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW2", "url": "https://www.uniprot.org/uniprotkb/Q9VUW2" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW2", "url": "https://www.uniprot.org/uniprotkb/Q9VUW2" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW2", "url": "https://www.uniprot.org/uniprotkb/Q9VUW2" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW2", "url": "https://www.uniprot.org/uniprotkb/Q9VUW2" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW2", "url": "https://www.uniprot.org/uniprotkb/Q9VUW2" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW2", "url": "https://www.uniprot.org/uniprotkb/Q9VUW2" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG17029", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG17029", "resource": "KEGG Pathway" }, { "id": "R-DME-1855183", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1855183", "resource": "Reactome", "description": "Synthesis of IP2, IP, and Ins in the cytosol" } ], "orthologs": [ { "uniprot_canonical_ac": "O14732-1", "protein_name": "Inositol monophosphatase 2", "gene_name": "IMPA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKPSGEDQAALAAGPWEECFQAAVQLALRAGQIIRKALTEEKRVSTKTSAADLVTETDHLVEDLIISELRERFPSHRFIAEEAAASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGVIYHCTEERLYTGRRGRGAFCNGQRLRVSGETDLSKALVLTEIGPKRDPATLKLFLSNMERLLHAKAHGVRVIGSSTLALCHLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSGGPLDLMACRVVAASTREMAMLIAQALQTINYGRDDEK", "length": 288 }, "evidence": [ { "id": "MGI:2149728", "url": "https://alliancegenome.org/gene/MGI:2149728#orthology", "database": "AGR" }, { "id": "HGNC:6051", "url": "https://alliancegenome.org/gene/HGNC:6051#orthology", "database": "AGR" }, { "id": "RGD:628692", "url": "https://alliancegenome.org/gene/RGD:628692#orthology", "database": "AGR" }, { "id": "FB:FBgn0036551", "url": "https://alliancegenome.org/gene/FB:FBgn0036551#orthology", "database": "AGR" }, { "id": "SGD:S000001088", "url": "https://alliancegenome.org/gene/SGD:S000001088#orthology", "database": "AGR" }, { "id": "SGD:S000002695", "url": "https://alliancegenome.org/gene/SGD:S000002695#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O55023-1", "protein_name": "Inositol monophosphatase 1", "gene_name": "Impa1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADPWQECMDYAVILARQAGEMIREALKNEMDVMIKSSPADLVTVTDQKVEKMLMSSIKEKYPCHSFIGEESVAAGEKTVFTESPTWFIDPIDGTTNFVHRFPFVAVSIGFLVNKEMEFGIVYSCVEDKMYTGRKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRKPETLRIVLSNMEKLCSIPIHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDMAGAGIIVTEAGGVLMDVTGGPFDLMSRRIIAANSITLAKRIAKEIEIIPLQRDDES", "length": 277 }, "evidence": [ { "id": "MGI:1933158", "url": "https://alliancegenome.org/gene/MGI:1933158#orthology", "database": "AGR" }, { "id": "HGNC:6050", "url": "https://alliancegenome.org/gene/HGNC:6050#orthology", "database": "AGR" }, { "id": "RGD:69254", "url": "https://alliancegenome.org/gene/RGD:69254#orthology", "database": "AGR" }, { "id": "FB:FBgn0036551", "url": "https://alliancegenome.org/gene/FB:FBgn0036551#orthology", "database": "AGR" }, { "id": "SGD:S000002695", "url": "https://alliancegenome.org/gene/SGD:S000002695#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P29218-1", "protein_name": "Inositol monophosphatase 1", "gene_name": "IMPA1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADPWQECMDYAVTLARQAGEVVCEAIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKEKYPSHSFIGEESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVVYSCVEGKMYTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNMEKLFCIPVHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVTGGPFDLMSRRVIAANNRILAERIAKEIQVIPLQRDDED", "length": 277 }, "evidence": [ { "id": "MGI:1933158", "url": "https://alliancegenome.org/gene/MGI:1933158#orthology", "database": "AGR" }, { "id": "HGNC:6050", "url": "https://alliancegenome.org/gene/HGNC:6050#orthology", "database": "AGR" }, { "id": "RGD:69254", "url": "https://alliancegenome.org/gene/RGD:69254#orthology", "database": "AGR" }, { "id": "FB:FBgn0036551", "url": "https://alliancegenome.org/gene/FB:FBgn0036551#orthology", "database": "AGR" }, { "id": "SGD:S000001088", "url": "https://alliancegenome.org/gene/SGD:S000001088#orthology", "database": "AGR" }, { "id": "SGD:S000002695", "url": "https://alliancegenome.org/gene/SGD:S000002695#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P38710-1", "protein_name": "Inositol monophosphatase 1", "gene_name": "INM1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTIDLASIEKFLCELATEKVGPIIKSKSGTQKDYDLKTGSRSVDIVTAIDKQVEKLIWESVKTQYPTFKFIGEESYVKGETVITDDPTFIIDPIDGTTNFVHDFPFSCTSLGLTVNKEPVVGVIYNPHINLLVSASKGNGMRVNNKDYDYKSKLESMGSLILNKSVVALQPGSAREGKNFQTKMATYEKLLSCDYGFVHGFRNLGSSAMTMAYIAMGYLDSYWDGGCYSWDVCAGWCILKEVGGRVVGANPGEWSIDVDNRTYLAVRGTINNESDEQTKYITDFWNCVDGHLKYD", "length": 295 }, "evidence": [ { "id": "MGI:2149728", "url": "https://alliancegenome.org/gene/MGI:2149728#orthology", "database": "AGR" }, { "id": "HGNC:6050", "url": "https://alliancegenome.org/gene/HGNC:6050#orthology", "database": "AGR" }, { "id": "HGNC:6051", "url": "https://alliancegenome.org/gene/HGNC:6051#orthology", "database": "AGR" }, { "id": "RGD:628692", "url": "https://alliancegenome.org/gene/RGD:628692#orthology", "database": "AGR" }, { "id": "FB:FBgn0036551", "url": "https://alliancegenome.org/gene/FB:FBgn0036551#orthology", "database": "AGR" }, { "id": "SGD:S000001088", "url": "https://alliancegenome.org/gene/SGD:S000001088#orthology", "database": "AGR" }, { "id": "Q9VUW2", "url": "https://omabrowser.org/oma/group/Q9VUW2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P97697-1", "protein_name": "Inositol monophosphatase 1", "gene_name": "Impa1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADPWQECMDYAVILARQAGEMIREALKNKMDVMIKSSPADLVTVTDQKVEKMLMSSIKEKYPYHSFIGEESVASGEKTVFTEQPTWIIDPIDGTTNFVHRFPFVAVSIGFVVNKEMEFGVVYSCVEDKMYTGRKGKGAFCNGQKLRVSQQEDITKSLLVTELGSSRKPETLRIVLSNMERLCSIPIHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDMAGAGIIVIEAGGVLLDVTGGPFDLMSRRIIAASNIALAERIAKELEIIPLQRDDES", "length": 277 }, "evidence": [ { "id": "MGI:1933158", "url": "https://alliancegenome.org/gene/MGI:1933158#orthology", "database": "AGR" }, { "id": "HGNC:6050", "url": "https://alliancegenome.org/gene/HGNC:6050#orthology", "database": "AGR" }, { "id": "RGD:69254", "url": "https://alliancegenome.org/gene/RGD:69254#orthology", "database": "AGR" }, { "id": "FB:FBgn0036551", "url": "https://alliancegenome.org/gene/FB:FBgn0036551#orthology", "database": "AGR" }, { "id": "SGD:S000002695", "url": "https://alliancegenome.org/gene/SGD:S000002695#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q05533-1", "protein_name": "Inositol monophosphatase 2", "gene_name": "INM2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVLTRQVLEEVENTFIELLRSKIGPLVKSHAGTNFCSYDDKANGVDLVTALDKQIESIIKENLTAKYPSFKFIGEETYVKGVTKITNGPTFIVDPIDGTTNFIHGYPYSCTSLGLAEMGKPVVGVVFNPHLNQLFHASKGNGAFLNDQEIKVSKRPLILQKSLIALEGGSERTEGSQGNFDKKMNTYKNLLSESGAFVHGFRSAGSAAMNICYVASGMLDAYWEGGCWAWDVCAGWCILEEAGGIMVGGNCGEWNIPLDRRCYLAIRGGCESMEQKRFAESFWPHVAGELEY", "length": 292 }, "evidence": [ { "id": "MGI:1933158", "url": "https://alliancegenome.org/gene/MGI:1933158#orthology", "database": "AGR" }, { "id": "MGI:2149728", "url": "https://alliancegenome.org/gene/MGI:2149728#orthology", "database": "AGR" }, { "id": "HGNC:6050", "url": "https://alliancegenome.org/gene/HGNC:6050#orthology", "database": "AGR" }, { "id": "HGNC:6051", "url": "https://alliancegenome.org/gene/HGNC:6051#orthology", "database": "AGR" }, { "id": "RGD:628692", "url": "https://alliancegenome.org/gene/RGD:628692#orthology", "database": "AGR" }, { "id": "RGD:69254", "url": "https://alliancegenome.org/gene/RGD:69254#orthology", "database": "AGR" }, { "id": "FB:FBgn0036551", "url": "https://alliancegenome.org/gene/FB:FBgn0036551#orthology", "database": "AGR" }, { "id": "SGD:S000002695", "url": "https://alliancegenome.org/gene/SGD:S000002695#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q7KTW5-1", "protein_name": "Inositol-1-monophosphatase", "gene_name": "Dmel\\CG9391", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSHNVDVEKCLEVASNLVSEAGRLIARNNEQRQDFVCKSNDIDLVTQTDKDVEQLLMDGIRRHFPEHKFIGEEESSGAEGVKKLTDEPTWIIDPVDGTMNFVHAFPHSCISVGLKVNKVTELGLVYNPILEQRFTARRGHGAFYNGRRIHVSGQKELGKALVTSEFGTTRDEAKMKVVHENFEKMAKKAHGLRVLGSAALNMSMVALGAADANYEFGIHAWDVCAGDLIVREAGGVVIDPAGGEFDIMSRRVLAAATPELAQEISKVLTQFNPLPRDD", "length": 278 }, "evidence": [ { "id": "MGI:1933158", "url": "https://alliancegenome.org/gene/MGI:1933158#orthology", "database": "AGR" }, { "id": "MGI:2149728", "url": "https://alliancegenome.org/gene/MGI:2149728#orthology", "database": "AGR" }, { "id": "HGNC:6050", "url": "https://alliancegenome.org/gene/HGNC:6050#orthology", "database": "AGR" }, { "id": "HGNC:6051", "url": "https://alliancegenome.org/gene/HGNC:6051#orthology", "database": "AGR" }, { "id": "RGD:628692", "url": "https://alliancegenome.org/gene/RGD:628692#orthology", "database": "AGR" }, { "id": "RGD:69254", "url": "https://alliancegenome.org/gene/RGD:69254#orthology", "database": "AGR" }, { "id": "SGD:S000001088", "url": "https://alliancegenome.org/gene/SGD:S000001088#orthology", "database": "AGR" }, { "id": "SGD:S000002695", "url": "https://alliancegenome.org/gene/SGD:S000002695#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8CIN7-1", "protein_name": "Inositol monophosphatase 2", "gene_name": "Impa2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKPNSEEEEELVQGVGPWDECFEVAVQLALRAGQIIRKALTEEKHVSTKTSAADLVTETDHRVEDLIVSELRKRFPSHRFIAEEATASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVHQELEFGVIHHCTEERLYTGRRGQGAFCNGQRLQVSRETDLAKALVLTEIGPKRDPDTLKVFLSNMERLLHAKAHGVRVIGSSTLALCYLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSGGPLDLMSCRVVAAGTREMAVLIAQALQTINYGRDDEK", "length": 290 }, "evidence": [ { "id": "MGI:2149728", "url": "https://alliancegenome.org/gene/MGI:2149728#orthology", "database": "AGR" }, { "id": "HGNC:6051", "url": "https://alliancegenome.org/gene/HGNC:6051#orthology", "database": "AGR" }, { "id": "RGD:628692", "url": "https://alliancegenome.org/gene/RGD:628692#orthology", "database": "AGR" }, { "id": "FB:FBgn0036551", "url": "https://alliancegenome.org/gene/FB:FBgn0036551#orthology", "database": "AGR" }, { "id": "SGD:S000001088", "url": "https://alliancegenome.org/gene/SGD:S000001088#orthology", "database": "AGR" }, { "id": "SGD:S000002695", "url": "https://alliancegenome.org/gene/SGD:S000002695#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q91UZ5-1", "protein_name": "Inositol monophosphatase 2", "gene_name": "Impa2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKPSSEEEGELVQGVGPWDECFEVAVQLALRAGQIIRKALTEEKRVSTKTSAADLVTETDHRVEDLIVSELRKRFPSHRFIAEEATASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVHQELEFGVIHHCTEERLYTGRRGQGAFCNGQRLQVSRETDLAKALVLTEIGPKRDPDTLKVFLSNMERLLHAKAHGVRVIGSSTLALCYLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSGGPLDLMSCRVVAAGTREMAVLIAQALQTINYGRDDEK", "length": 290 }, "evidence": [ { "id": "MGI:2149728", "url": "https://alliancegenome.org/gene/MGI:2149728#orthology", "database": "AGR" }, { "id": "HGNC:6051", "url": "https://alliancegenome.org/gene/HGNC:6051#orthology", "database": "AGR" }, { "id": "RGD:628692", "url": "https://alliancegenome.org/gene/RGD:628692#orthology", "database": "AGR" }, { "id": "FB:FBgn0036551", "url": "https://alliancegenome.org/gene/FB:FBgn0036551#orthology", "database": "AGR" }, { "id": "SGD:S000001088", "url": "https://alliancegenome.org/gene/SGD:S000001088#orthology", "database": "AGR" }, { "id": "SGD:S000002695", "url": "https://alliancegenome.org/gene/SGD:S000002695#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VP62-1", "protein_name": "inositol-phosphate phosphatase", "gene_name": "Dmel\\CG9389", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVDEKLPPSKEPAERPPDQTTPGNAATRFGLEDHEATQQDARVNTLRQAEERRGSMVPPDKRAMSMKMSQARLHTINDPNRTGTHSAEATTPPAKPAVNISSRSSLVRGVAPDLPPKPQRPSDSEADLESSDVDRPSAKRKSEKALADVSTSSSEESEKRVPPAAASAPPPAQAEPQWKSIDFAASEAEPIAPPAPRPEDVPLPPPMMSSLPTDGSPDDVQSINSKLTNTDITFHPSKVFASKATNTSGMLYSDEENEPEEEEFPKLPDQFSASDLDTLFLLACREVKKAGAIALAENKKNQEYTTKKHTNDIVTPTDNIVEESFIKAISSRYPNHQFIAEERISKSETGMVTLTDDPTWIIDPIDGTMNFVHHFPYYCISVAYLVNQETQFGIIYNPPMKNMYTAQLGKGAQMNGEMIRTTGQTNLSAAMVLQEYSSGSNEARNQVATENSQRLVKKTHAMRSIGSSAMCLAMVASGVADAFYNFGLHVWDMAAGALIVTEAGGVVMDPAGEELDIMSRRCLAASTDYLALELGNCLQQNYPSPRDDEPRSVNPNEYGPAPETRDFTSQTDFPDSDTPETTDTEIGGEKSATPAN", "length": 596 }, "evidence": [ { "id": "MGI:2149728", "url": "https://alliancegenome.org/gene/MGI:2149728#orthology", "database": "AGR" }, { "id": "HGNC:6051", "url": "https://alliancegenome.org/gene/HGNC:6051#orthology", "database": "AGR" }, { "id": "RGD:628692", "url": "https://alliancegenome.org/gene/RGD:628692#orthology", "database": "AGR" }, { "id": "SGD:S000001088", "url": "https://alliancegenome.org/gene/SGD:S000001088#orthology", "database": "AGR" }, { "id": "SGD:S000002695", "url": "https://alliancegenome.org/gene/SGD:S000002695#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VUW1-1", "protein_name": "Inositol-1-monophosphatase", "gene_name": "cg17026", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAASKSQIEELYDFIYPLAVRAGEILLEGYQNAGKAVALKDGEFYNVVTAYDNQIEEFLVEKILARYPDHKFIGEEDTHKNDNVTKELTDAPTWIIDPIDGTSNFIKQIPHVSVSIGLSIKKQIVLGVVNNPAQNKLYTAKLGQGAFCNGKPIQVSSCEHLNDANVAYEVCLLHAPKIRNKHIKRIYHVGSNARRLLAYSAVVDSLCMVAAGNLDAFHIEDMYPWDCAAGYLLIREAGGVVTHPYGGPFDIMKPDLICAGTETLRAEIEHLIRKADQEKHVGGE", "length": 284 }, "evidence": [ { "id": "MGI:1933158", "url": "https://alliancegenome.org/gene/MGI:1933158#orthology", "database": "AGR" }, { "id": "MGI:2149728", "url": "https://alliancegenome.org/gene/MGI:2149728#orthology", "database": "AGR" }, { "id": "HGNC:6050", "url": "https://alliancegenome.org/gene/HGNC:6050#orthology", "database": "AGR" }, { "id": "HGNC:6051", "url": "https://alliancegenome.org/gene/HGNC:6051#orthology", "database": "AGR" }, { "id": "RGD:628692", "url": "https://alliancegenome.org/gene/RGD:628692#orthology", "database": "AGR" }, { "id": "RGD:69254", "url": "https://alliancegenome.org/gene/RGD:69254#orthology", "database": "AGR" }, { "id": "SGD:S000001088", "url": "https://alliancegenome.org/gene/SGD:S000001088#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VUW3-1", "protein_name": "Inositol-1-monophosphatase", "gene_name": "IMP", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSYRIGEEKLEVYYQVSLELVRKCGPLFLEGFQKPKTDYEVKSAFYDLVTVYDKQIEATLTDGLLKTFPESKIIGEEAMANAKTPPELTDAPTWIIDPIDGTNNYVRKIPHCCISVGLAINKELVLGIVYNPSANELYSAWQGHGAYLNGQPIEVSNAKKINQALVCYEISLIVVSKGRDKNVKRLYKLASSATGTRSFGCAALTLCYIAAGRCDAYHVENLKPWDLAGGAVILREAGGRVYHTSGARFDVMKPDCVCTSSEELAKSVIQLIEGADQISGYTFK", "length": 284 }, "evidence": [ { "id": "MGI:1933158", "url": "https://alliancegenome.org/gene/MGI:1933158#orthology", "database": "AGR" }, { "id": "MGI:2149728", "url": "https://alliancegenome.org/gene/MGI:2149728#orthology", "database": "AGR" }, { "id": "HGNC:6050", "url": "https://alliancegenome.org/gene/HGNC:6050#orthology", "database": "AGR" }, { "id": "HGNC:6051", "url": "https://alliancegenome.org/gene/HGNC:6051#orthology", "database": "AGR" }, { "id": "RGD:628692", "url": "https://alliancegenome.org/gene/RGD:628692#orthology", "database": "AGR" }, { "id": "RGD:69254", "url": "https://alliancegenome.org/gene/RGD:69254#orthology", "database": "AGR" }, { "id": "SGD:S000001088", "url": "https://alliancegenome.org/gene/SGD:S000001088#orthology", "database": "AGR" }, { "id": "SGD:S000002695", "url": "https://alliancegenome.org/gene/SGD:S000002695#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VUW4-1", "protein_name": "Inositol-1-monophosphatase", "gene_name": "IMP", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAGVSQADIEELYNFIHPLAIKAGEILMEGYEMASKNVSIKGDFYDVVTDYDNKIEDFLMEKILARYPDHKFIGEEETAKNNNVSGELTNAPTWIIDPIDGTSNFIKQIPHVCVSIGLAINKQIVVGVINNPVQKKLFTTKLGQGAFCNGKPIHVSSCESVKDANVAYEVSLLHVHSVANKHIKRIYHVGLNARRLVAYSCVVDELCMVAAGNLDAFYIEDMYPWDCAAGSLLVKEAGGVVTHPFGGPFDIMKPDLICAGTEKLRKEIEDLLRKGDQEESVGGKPVQK", "length": 288 }, "evidence": [ { "id": "MGI:1933158", "url": "https://alliancegenome.org/gene/MGI:1933158#orthology", "database": "AGR" }, { "id": "MGI:2149728", "url": "https://alliancegenome.org/gene/MGI:2149728#orthology", "database": "AGR" }, { "id": "HGNC:6050", "url": "https://alliancegenome.org/gene/HGNC:6050#orthology", "database": "AGR" }, { "id": "HGNC:6051", "url": "https://alliancegenome.org/gene/HGNC:6051#orthology", "database": "AGR" }, { "id": "RGD:628692", "url": "https://alliancegenome.org/gene/RGD:628692#orthology", "database": "AGR" }, { "id": "RGD:69254", "url": "https://alliancegenome.org/gene/RGD:69254#orthology", "database": "AGR" }, { "id": "SGD:S000001088", "url": "https://alliancegenome.org/gene/SGD:S000001088#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "inositol metabolic process", "id": "GO:0006020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006020", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW2", "url": "https://www.uniprot.org/uniprotkb/Q9VUW2" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW2", "url": "https://www.uniprot.org/uniprotkb/Q9VUW2" } ], "pmid": "" }, { "name": "inositol biosynthetic process", "id": "GO:0006021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006021", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW2", "url": "https://www.uniprot.org/uniprotkb/Q9VUW2" } ], "pmid": "" }, { "name": "phosphatidylinositol phosphate biosynthetic process", "id": "GO:0046854", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046854", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW2", "url": "https://www.uniprot.org/uniprotkb/Q9VUW2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "inositol monophosphate phosphatase activity", "id": "GO:0052834", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052834", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW2", "url": "https://www.uniprot.org/uniprotkb/Q9VUW2" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW2", "url": "https://www.uniprot.org/uniprotkb/Q9VUW2" } ], "pmid": "" }, { "name": "inositol monophosphate 1-phosphatase activity", "id": "GO:0008934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008934", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW2", "url": "https://www.uniprot.org/uniprotkb/Q9VUW2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW2", "url": "https://www.uniprot.org/uniprotkb/Q9VUW2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "24056", "name": "", "equation": "a myo-inositol phosphate + H2O = myo-inositol + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VYF2-1", "Q7KTW5-1", "Q9VP62-1", "Q9VUW1-1", "Q9VUW2-1", "Q9VUW4-1", "Q9VUW3-1" ], "evidence": [ { "id": "24056", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/24056" } ] }, { "id": "R-DME-1855154", "name": "I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-870330" ], "output_participant_list": [], "enzyme_list": [ "Q9VP62-1", "Q7KTW5-1", "Q9VUW3-1", "Q9VUW1-1", "Q9VUW2-1", "Q9VUW4-1" ], "evidence": [ { "id": "R-DME-1855154", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1855154" } ] }, { "id": "R-DME-1855210", "name": "I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-1629731" ], "output_participant_list": [], "enzyme_list": [ "Q9VP62-1", "Q7KTW5-1", "Q9VUW3-1", "Q9VUW1-1", "Q9VUW2-1", "Q9VUW4-1" ], "evidence": [ { "id": "R-DME-1855210", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1855210" } ] }, { "id": "R-DME-1855211", "name": "I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-1629753" ], "output_participant_list": [], "enzyme_list": [ "Q9VP62-1", "Q7KTW5-1", "Q9VUW3-1", "Q9VUW1-1", "Q9VUW2-1", "Q9VUW4-1" ], "evidence": [ { "id": "R-DME-1855211", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1855211" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-1629731", "participant_name": "I3P [cytosol]", "crossref": [ { "id": "58401", "database": "ChEBI", "url": "" }, { "id": "ZINC000100028278", "database": "ZINC", "url": "" }, { "id": "C04006", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-1629753", "participant_name": "I4P [cytosol]", "crossref": [ { "id": "58469", "database": "ChEBI", "url": "" }, { "id": "ZINC000100016164", "database": "ZINC", "url": "" }, { "id": "C03546", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-870330", 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"https://www.alliancegenome.org/disease/DOID:5419" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VUW4", "url": "https://www.uniprot.org/uniprotkb/Q9VUW4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "IMP", "url": "https://www.uniprot.org/uniprotkb/Q9VUW4", "locus": { "chromosome": "3L", "start_pos": 15980004, "end_pos": 15978524, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0036552", "url": "https://www.ensemblgenomes.org/id/FBgn0036552" } ] } } ], "crossref": [ { "id": "FB:FBgn0036553", "url": "https://alliancegenome.org/gene/FB:FBgn0036553", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0036553", "url": "https://bgee.org/?page=gene&gene_id=FBgn0036553", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01639", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01639", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0036553", "url": "https://flybase.org/reports/FBgn0036553", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "39742", "url": "https://www.ncbi.nlm.nih.gov/gene/39742", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VUW4", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VUW4*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR000760", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000760", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020550", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020550", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020552", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020552", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020583", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020583", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033942", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033942", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG17027", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG17027", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EDFLMEQ", "url": "https://omabrowser.org/oma/group/EDFLMEQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VUW4", "url": "https://www.orthodb.org/?gene=Q9VUW4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20854", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20854", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20854:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20854:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00459", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00459", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-1855183", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1855183", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001261909", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261909", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "24056", "url": "https://www.rhea-db.org/rhea/24056", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q9VUW4", "url": "https://www.uniprot.org/uniprotkb/Q9VUW4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VUW4-1", "url": "https://www.uniprot.org/uniprotkb/Q9VUW4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGVSQADIEELYNFIHPLAIKAGEILMEGYEMASKNVSIKGDFYDVVTDYDNKIEDFLMEKILARYPDHKFIGEEETAKNNNVSGELTNAPTWIIDPIDGTSNFIKQIPHVCVSIGLAINKQIVVGVINNPVQKKLFTTKLGQGAFCNGKPIHVSSCESVKDANVAYEVSLLHVHSVANKHIKRIYHVGLNARRLVAYSCVVDELCMVAAGNLDAFYIEDMYPWDCAAGSLLVKEAGGVVTHPFGGPFDIMKPDLICAGTEKLRKEIEDLLRKGDQEESVGGKPVQK", "length": 288, "header": "tr|Q9VUW4-1|Q9VUW4_DROME Isoform 1 of Inositol-1-monophosphatase OS=Drosophila melanogaster OX=7227 GN=IMP PE=1 SV=1 CANONICAL=Q9VUW4-1" }, "isoforms": [ { "isoform_ac": "Q9VUW4-1", "url": "https://www.uniprot.org/uniprotkb/Q9VUW4/entry#Q9VUW4-1", "sequence": { "sequence": "MAGVSQADIEELYNFIHPLAIKAGEILMEGYEMASKNVSIKGDFYDVVTDYDNKIEDFLMEKILARYPDHKFIGEEETAKNNNVSGELTNAPTWIIDPIDGTSNFIKQIPHVCVSIGLAINKQIVVGVINNPVQKKLFTTKLGQGAFCNGKPIHVSSCESVKDANVAYEVSLLHVHSVANKHIKRIYHVGLNARRLVAYSCVVDELCMVAAGNLDAFYIEDMYPWDCAAGSLLVKEAGGVVTHPFGGPFDIMKPDLICAGTEKLRKEIEDLLRKGDQEESVGGKPVQK", "length": 288, "header": "tr|Q9VUW4-1|Q9VUW4_DROME Isoform 1 of Inositol-1-monophosphatase OS=Drosophila melanogaster OX=7227 GN=IMP PE=1 SV=1 CANONICAL=Q9VUW4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW4", "url": "https://www.uniprot.org/uniprotkb/Q9VUW4" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW4", "url": "https://www.uniprot.org/uniprotkb/Q9VUW4" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW4", "url": "https://www.uniprot.org/uniprotkb/Q9VUW4" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW4", "url": "https://www.uniprot.org/uniprotkb/Q9VUW4" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW4", "url": "https://www.uniprot.org/uniprotkb/Q9VUW4" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW4", "url": "https://www.uniprot.org/uniprotkb/Q9VUW4" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW4", "url": "https://www.uniprot.org/uniprotkb/Q9VUW4" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW4", "url": "https://www.uniprot.org/uniprotkb/Q9VUW4" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW4", "url": "https://www.uniprot.org/uniprotkb/Q9VUW4" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW4", "url": "https://www.uniprot.org/uniprotkb/Q9VUW4" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW4", "url": "https://www.uniprot.org/uniprotkb/Q9VUW4" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG17027", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG17027", "resource": "KEGG Pathway" }, { "id": "R-DME-1855183", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1855183", "resource": "Reactome", "description": "Synthesis of IP2, IP, and Ins in the cytosol" } ], "orthologs": [ { "uniprot_canonical_ac": "O14732-1", "protein_name": "Inositol monophosphatase 2", "gene_name": "IMPA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKPSGEDQAALAAGPWEECFQAAVQLALRAGQIIRKALTEEKRVSTKTSAADLVTETDHLVEDLIISELRERFPSHRFIAEEAAASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGVIYHCTEERLYTGRRGRGAFCNGQRLRVSGETDLSKALVLTEIGPKRDPATLKLFLSNMERLLHAKAHGVRVIGSSTLALCHLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSGGPLDLMACRVVAASTREMAMLIAQALQTINYGRDDEK", "length": 288 }, "evidence": [ { "id": "MGI:2149728", "url": "https://alliancegenome.org/gene/MGI:2149728#orthology", "database": "AGR" }, { "id": "HGNC:6051", "url": "https://alliancegenome.org/gene/HGNC:6051#orthology", "database": "AGR" }, { "id": "RGD:628692", "url": "https://alliancegenome.org/gene/RGD:628692#orthology", "database": "AGR" }, { "id": "FB:FBgn0036553", "url": "https://alliancegenome.org/gene/FB:FBgn0036553#orthology", "database": "AGR" }, { "id": "SGD:S000001088", "url": "https://alliancegenome.org/gene/SGD:S000001088#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O55023-1", "protein_name": "Inositol monophosphatase 1", "gene_name": "Impa1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADPWQECMDYAVILARQAGEMIREALKNEMDVMIKSSPADLVTVTDQKVEKMLMSSIKEKYPCHSFIGEESVAAGEKTVFTESPTWFIDPIDGTTNFVHRFPFVAVSIGFLVNKEMEFGIVYSCVEDKMYTGRKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRKPETLRIVLSNMEKLCSIPIHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDMAGAGIIVTEAGGVLMDVTGGPFDLMSRRIIAANSITLAKRIAKEIEIIPLQRDDES", "length": 277 }, "evidence": [ { "id": "MGI:1933158", "url": "https://alliancegenome.org/gene/MGI:1933158#orthology", "database": "AGR" }, { "id": "HGNC:6050", "url": "https://alliancegenome.org/gene/HGNC:6050#orthology", "database": "AGR" }, { "id": "RGD:69254", "url": "https://alliancegenome.org/gene/RGD:69254#orthology", "database": "AGR" }, { "id": "FB:FBgn0036553", "url": "https://alliancegenome.org/gene/FB:FBgn0036553#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P29218-1", "protein_name": "Inositol monophosphatase 1", "gene_name": "IMPA1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADPWQECMDYAVTLARQAGEVVCEAIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKEKYPSHSFIGEESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVVYSCVEGKMYTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNMEKLFCIPVHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVTGGPFDLMSRRVIAANNRILAERIAKEIQVIPLQRDDED", "length": 277 }, "evidence": [ { "id": "MGI:1933158", "url": "https://alliancegenome.org/gene/MGI:1933158#orthology", "database": "AGR" }, { "id": "HGNC:6050", "url": "https://alliancegenome.org/gene/HGNC:6050#orthology", "database": "AGR" }, { "id": "RGD:69254", "url": "https://alliancegenome.org/gene/RGD:69254#orthology", "database": "AGR" }, { "id": "FB:FBgn0036553", "url": "https://alliancegenome.org/gene/FB:FBgn0036553#orthology", "database": "AGR" }, { "id": "SGD:S000001088", "url": "https://alliancegenome.org/gene/SGD:S000001088#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P38710-1", "protein_name": "Inositol monophosphatase 1", "gene_name": "INM1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTIDLASIEKFLCELATEKVGPIIKSKSGTQKDYDLKTGSRSVDIVTAIDKQVEKLIWESVKTQYPTFKFIGEESYVKGETVITDDPTFIIDPIDGTTNFVHDFPFSCTSLGLTVNKEPVVGVIYNPHINLLVSASKGNGMRVNNKDYDYKSKLESMGSLILNKSVVALQPGSAREGKNFQTKMATYEKLLSCDYGFVHGFRNLGSSAMTMAYIAMGYLDSYWDGGCYSWDVCAGWCILKEVGGRVVGANPGEWSIDVDNRTYLAVRGTINNESDEQTKYITDFWNCVDGHLKYD", "length": 295 }, "evidence": [ { "id": "MGI:2149728", "url": "https://alliancegenome.org/gene/MGI:2149728#orthology", "database": "AGR" }, { "id": "HGNC:6050", "url": "https://alliancegenome.org/gene/HGNC:6050#orthology", "database": "AGR" }, { "id": "HGNC:6051", "url": "https://alliancegenome.org/gene/HGNC:6051#orthology", "database": "AGR" }, { "id": "RGD:628692", "url": "https://alliancegenome.org/gene/RGD:628692#orthology", "database": "AGR" }, { "id": "FB:FBgn0036553", "url": "https://alliancegenome.org/gene/FB:FBgn0036553#orthology", "database": "AGR" }, { "id": "SGD:S000001088", "url": "https://alliancegenome.org/gene/SGD:S000001088#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P97697-1", "protein_name": "Inositol monophosphatase 1", "gene_name": "Impa1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADPWQECMDYAVILARQAGEMIREALKNKMDVMIKSSPADLVTVTDQKVEKMLMSSIKEKYPYHSFIGEESVASGEKTVFTEQPTWIIDPIDGTTNFVHRFPFVAVSIGFVVNKEMEFGVVYSCVEDKMYTGRKGKGAFCNGQKLRVSQQEDITKSLLVTELGSSRKPETLRIVLSNMERLCSIPIHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDMAGAGIIVIEAGGVLLDVTGGPFDLMSRRIIAASNIALAERIAKELEIIPLQRDDES", "length": 277 }, "evidence": [ { "id": "MGI:1933158", "url": "https://alliancegenome.org/gene/MGI:1933158#orthology", "database": "AGR" }, { "id": "HGNC:6050", "url": "https://alliancegenome.org/gene/HGNC:6050#orthology", "database": "AGR" }, { "id": "RGD:69254", "url": "https://alliancegenome.org/gene/RGD:69254#orthology", "database": "AGR" }, { "id": "FB:FBgn0036553", "url": "https://alliancegenome.org/gene/FB:FBgn0036553#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q05533-1", "protein_name": "Inositol monophosphatase 2", "gene_name": "INM2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVLTRQVLEEVENTFIELLRSKIGPLVKSHAGTNFCSYDDKANGVDLVTALDKQIESIIKENLTAKYPSFKFIGEETYVKGVTKITNGPTFIVDPIDGTTNFIHGYPYSCTSLGLAEMGKPVVGVVFNPHLNQLFHASKGNGAFLNDQEIKVSKRPLILQKSLIALEGGSERTEGSQGNFDKKMNTYKNLLSESGAFVHGFRSAGSAAMNICYVASGMLDAYWEGGCWAWDVCAGWCILEEAGGIMVGGNCGEWNIPLDRRCYLAIRGGCESMEQKRFAESFWPHVAGELEY", "length": 292 }, "evidence": [ { "id": "MGI:1933158", "url": "https://alliancegenome.org/gene/MGI:1933158#orthology", "database": "AGR" }, { "id": "MGI:2149728", "url": "https://alliancegenome.org/gene/MGI:2149728#orthology", "database": "AGR" }, { "id": "HGNC:6050", "url": "https://alliancegenome.org/gene/HGNC:6050#orthology", "database": "AGR" }, { "id": "HGNC:6051", "url": "https://alliancegenome.org/gene/HGNC:6051#orthology", "database": "AGR" }, { "id": "RGD:628692", "url": "https://alliancegenome.org/gene/RGD:628692#orthology", "database": "AGR" }, { "id": "RGD:69254", "url": "https://alliancegenome.org/gene/RGD:69254#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q7KTW5-1", "protein_name": "Inositol-1-monophosphatase", "gene_name": "Dmel\\CG9391", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSHNVDVEKCLEVASNLVSEAGRLIARNNEQRQDFVCKSNDIDLVTQTDKDVEQLLMDGIRRHFPEHKFIGEEESSGAEGVKKLTDEPTWIIDPVDGTMNFVHAFPHSCISVGLKVNKVTELGLVYNPILEQRFTARRGHGAFYNGRRIHVSGQKELGKALVTSEFGTTRDEAKMKVVHENFEKMAKKAHGLRVLGSAALNMSMVALGAADANYEFGIHAWDVCAGDLIVREAGGVVIDPAGGEFDIMSRRVLAAATPELAQEISKVLTQFNPLPRDD", "length": 278 }, "evidence": [ { "id": "MGI:1933158", "url": "https://alliancegenome.org/gene/MGI:1933158#orthology", "database": "AGR" }, { "id": "MGI:2149728", "url": "https://alliancegenome.org/gene/MGI:2149728#orthology", "database": "AGR" }, { "id": "HGNC:6050", "url": "https://alliancegenome.org/gene/HGNC:6050#orthology", "database": "AGR" }, { "id": "HGNC:6051", "url": "https://alliancegenome.org/gene/HGNC:6051#orthology", "database": "AGR" }, { "id": "RGD:628692", "url": "https://alliancegenome.org/gene/RGD:628692#orthology", "database": "AGR" }, { "id": "RGD:69254", "url": "https://alliancegenome.org/gene/RGD:69254#orthology", "database": "AGR" }, { "id": "SGD:S000001088", "url": "https://alliancegenome.org/gene/SGD:S000001088#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8CIN7-1", "protein_name": "Inositol monophosphatase 2", "gene_name": "Impa2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKPNSEEEEELVQGVGPWDECFEVAVQLALRAGQIIRKALTEEKHVSTKTSAADLVTETDHRVEDLIVSELRKRFPSHRFIAEEATASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVHQELEFGVIHHCTEERLYTGRRGQGAFCNGQRLQVSRETDLAKALVLTEIGPKRDPDTLKVFLSNMERLLHAKAHGVRVIGSSTLALCYLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSGGPLDLMSCRVVAAGTREMAVLIAQALQTINYGRDDEK", "length": 290 }, "evidence": [ { "id": "MGI:2149728", "url": "https://alliancegenome.org/gene/MGI:2149728#orthology", "database": "AGR" }, { "id": "HGNC:6051", "url": "https://alliancegenome.org/gene/HGNC:6051#orthology", "database": "AGR" }, { "id": "RGD:628692", "url": "https://alliancegenome.org/gene/RGD:628692#orthology", "database": "AGR" }, { "id": "FB:FBgn0036553", "url": "https://alliancegenome.org/gene/FB:FBgn0036553#orthology", "database": "AGR" }, { "id": "SGD:S000001088", "url": "https://alliancegenome.org/gene/SGD:S000001088#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q91UZ5-1", "protein_name": "Inositol monophosphatase 2", "gene_name": "Impa2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKPSSEEEGELVQGVGPWDECFEVAVQLALRAGQIIRKALTEEKRVSTKTSAADLVTETDHRVEDLIVSELRKRFPSHRFIAEEATASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVHQELEFGVIHHCTEERLYTGRRGQGAFCNGQRLQVSRETDLAKALVLTEIGPKRDPDTLKVFLSNMERLLHAKAHGVRVIGSSTLALCYLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSGGPLDLMSCRVVAAGTREMAVLIAQALQTINYGRDDEK", "length": 290 }, "evidence": [ { "id": "MGI:2149728", "url": "https://alliancegenome.org/gene/MGI:2149728#orthology", "database": "AGR" }, { "id": "HGNC:6051", "url": "https://alliancegenome.org/gene/HGNC:6051#orthology", "database": "AGR" }, { "id": "RGD:628692", "url": "https://alliancegenome.org/gene/RGD:628692#orthology", "database": "AGR" }, { "id": "FB:FBgn0036553", "url": "https://alliancegenome.org/gene/FB:FBgn0036553#orthology", "database": "AGR" }, { "id": "SGD:S000001088", "url": "https://alliancegenome.org/gene/SGD:S000001088#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VP62-1", "protein_name": "inositol-phosphate phosphatase", "gene_name": "Dmel\\CG9389", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVDEKLPPSKEPAERPPDQTTPGNAATRFGLEDHEATQQDARVNTLRQAEERRGSMVPPDKRAMSMKMSQARLHTINDPNRTGTHSAEATTPPAKPAVNISSRSSLVRGVAPDLPPKPQRPSDSEADLESSDVDRPSAKRKSEKALADVSTSSSEESEKRVPPAAASAPPPAQAEPQWKSIDFAASEAEPIAPPAPRPEDVPLPPPMMSSLPTDGSPDDVQSINSKLTNTDITFHPSKVFASKATNTSGMLYSDEENEPEEEEFPKLPDQFSASDLDTLFLLACREVKKAGAIALAENKKNQEYTTKKHTNDIVTPTDNIVEESFIKAISSRYPNHQFIAEERISKSETGMVTLTDDPTWIIDPIDGTMNFVHHFPYYCISVAYLVNQETQFGIIYNPPMKNMYTAQLGKGAQMNGEMIRTTGQTNLSAAMVLQEYSSGSNEARNQVATENSQRLVKKTHAMRSIGSSAMCLAMVASGVADAFYNFGLHVWDMAAGALIVTEAGGVVMDPAGEELDIMSRRCLAASTDYLALELGNCLQQNYPSPRDDEPRSVNPNEYGPAPETRDFTSQTDFPDSDTPETTDTEIGGEKSATPAN", "length": 596 }, "evidence": [ { "id": "MGI:2149728", "url": "https://alliancegenome.org/gene/MGI:2149728#orthology", "database": "AGR" }, { "id": "HGNC:6051", "url": "https://alliancegenome.org/gene/HGNC:6051#orthology", "database": "AGR" }, { "id": "RGD:628692", "url": "https://alliancegenome.org/gene/RGD:628692#orthology", "database": "AGR" }, { "id": "SGD:S000001088", "url": "https://alliancegenome.org/gene/SGD:S000001088#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VUW1-1", "protein_name": "Inositol-1-monophosphatase", "gene_name": "cg17026", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAASKSQIEELYDFIYPLAVRAGEILLEGYQNAGKAVALKDGEFYNVVTAYDNQIEEFLVEKILARYPDHKFIGEEDTHKNDNVTKELTDAPTWIIDPIDGTSNFIKQIPHVSVSIGLSIKKQIVLGVVNNPAQNKLYTAKLGQGAFCNGKPIQVSSCEHLNDANVAYEVCLLHAPKIRNKHIKRIYHVGSNARRLLAYSAVVDSLCMVAAGNLDAFHIEDMYPWDCAAGYLLIREAGGVVTHPYGGPFDIMKPDLICAGTETLRAEIEHLIRKADQEKHVGGE", "length": 284 }, "evidence": [ { "id": "MGI:1933158", "url": "https://alliancegenome.org/gene/MGI:1933158#orthology", "database": "AGR" }, { "id": "MGI:2149728", "url": "https://alliancegenome.org/gene/MGI:2149728#orthology", "database": "AGR" }, { "id": "HGNC:6050", "url": "https://alliancegenome.org/gene/HGNC:6050#orthology", "database": "AGR" }, { "id": "HGNC:6051", "url": "https://alliancegenome.org/gene/HGNC:6051#orthology", "database": "AGR" }, { "id": "RGD:628692", "url": "https://alliancegenome.org/gene/RGD:628692#orthology", "database": "AGR" }, { "id": "RGD:69254", "url": "https://alliancegenome.org/gene/RGD:69254#orthology", "database": "AGR" }, { "id": "SGD:S000001088", "url": "https://alliancegenome.org/gene/SGD:S000001088#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VUW2-1", "protein_name": "Inositol-1-monophosphatase", "gene_name": "IMP", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSSAVSESKLKEYYDVALKLVLKCGPLMQEGYQKAKTEYKVKADFYDLVTVYDKQIEDILTEGLVAAFPESLIIGEEESAVSQRQAELTDAPTWIIDPIDGTTNFIHRIPHCCISVGLAINKELVVGIIYNPPANELFSAYKGHGAYLNGEPIHTSKVTTIKQAVIAYEISLIHAAGVRDKNVKRLYKMASNATGTRCFGSAALTLCYVATGQCDAYHVEDLKPWDIAAGAIILTEAGGTVCHTSGSKFDVMKPDCVCAATPELAKNVISLIEEAGQITEYTFK", "length": 284 }, "evidence": [ { "id": "MGI:1933158", "url": "https://alliancegenome.org/gene/MGI:1933158#orthology", "database": "AGR" }, { "id": "MGI:2149728", "url": "https://alliancegenome.org/gene/MGI:2149728#orthology", "database": "AGR" }, { "id": "HGNC:6050", "url": "https://alliancegenome.org/gene/HGNC:6050#orthology", "database": "AGR" }, { "id": "HGNC:6051", "url": "https://alliancegenome.org/gene/HGNC:6051#orthology", "database": "AGR" }, { "id": "RGD:628692", "url": "https://alliancegenome.org/gene/RGD:628692#orthology", "database": "AGR" }, { "id": "RGD:69254", "url": "https://alliancegenome.org/gene/RGD:69254#orthology", "database": "AGR" }, { "id": "SGD:S000001088", "url": "https://alliancegenome.org/gene/SGD:S000001088#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VUW3-1", "protein_name": "Inositol-1-monophosphatase", "gene_name": "IMP", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSYRIGEEKLEVYYQVSLELVRKCGPLFLEGFQKPKTDYEVKSAFYDLVTVYDKQIEATLTDGLLKTFPESKIIGEEAMANAKTPPELTDAPTWIIDPIDGTNNYVRKIPHCCISVGLAINKELVLGIVYNPSANELYSAWQGHGAYLNGQPIEVSNAKKINQALVCYEISLIVVSKGRDKNVKRLYKLASSATGTRSFGCAALTLCYIAAGRCDAYHVENLKPWDLAGGAVILREAGGRVYHTSGARFDVMKPDCVCTSSEELAKSVIQLIEGADQISGYTFK", "length": 284 }, "evidence": [ { "id": "MGI:1933158", "url": "https://alliancegenome.org/gene/MGI:1933158#orthology", "database": "AGR" }, { "id": "MGI:2149728", "url": "https://alliancegenome.org/gene/MGI:2149728#orthology", "database": "AGR" }, { "id": "HGNC:6050", "url": "https://alliancegenome.org/gene/HGNC:6050#orthology", "database": "AGR" }, { "id": "HGNC:6051", "url": "https://alliancegenome.org/gene/HGNC:6051#orthology", "database": "AGR" }, { "id": "RGD:628692", "url": "https://alliancegenome.org/gene/RGD:628692#orthology", "database": "AGR" }, { "id": "RGD:69254", "url": "https://alliancegenome.org/gene/RGD:69254#orthology", "database": "AGR" }, { "id": "SGD:S000001088", "url": "https://alliancegenome.org/gene/SGD:S000001088#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "inositol metabolic process", "id": "GO:0006020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006020", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW4", "url": "https://www.uniprot.org/uniprotkb/Q9VUW4" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW4", "url": "https://www.uniprot.org/uniprotkb/Q9VUW4" } ], "pmid": "" }, { "name": "inositol biosynthetic process", "id": "GO:0006021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006021", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW4", "url": "https://www.uniprot.org/uniprotkb/Q9VUW4" } ], "pmid": "" }, { "name": "phosphatidylinositol phosphate biosynthetic process", "id": "GO:0046854", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046854", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW4", "url": "https://www.uniprot.org/uniprotkb/Q9VUW4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "inositol monophosphate phosphatase activity", "id": "GO:0052834", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052834", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW4", "url": "https://www.uniprot.org/uniprotkb/Q9VUW4" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW4", "url": "https://www.uniprot.org/uniprotkb/Q9VUW4" } ], "pmid": "" }, { "name": "inositol monophosphate 1-phosphatase activity", "id": "GO:0008934", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008934", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW4", "url": "https://www.uniprot.org/uniprotkb/Q9VUW4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VUW4", "url": "https://www.uniprot.org/uniprotkb/Q9VUW4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 37, "end_pos": 39, "annotation": "n_glycosylation_sequon" }, { "start_pos": 83, "end_pos": 85, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "24056", "name": "", "equation": "a myo-inositol phosphate + H2O = myo-inositol + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VYF2-1", "Q7KTW5-1", "Q9VP62-1", "Q9VUW1-1", "Q9VUW2-1", "Q9VUW4-1", "Q9VUW3-1" ], "evidence": [ { "id": "24056", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/24056" } ] }, { "id": "R-DME-1855154", "name": "I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-870330" ], "output_participant_list": [], "enzyme_list": [ "Q9VP62-1", "Q7KTW5-1", "Q9VUW3-1", "Q9VUW1-1", "Q9VUW2-1", "Q9VUW4-1" ], "evidence": [ { "id": "R-DME-1855154", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1855154" } ] }, { "id": "R-DME-1855210", "name": "I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-1629731" ], "output_participant_list": [], "enzyme_list": [ "Q9VP62-1", "Q7KTW5-1", "Q9VUW3-1", "Q9VUW1-1", "Q9VUW2-1", "Q9VUW4-1" ], "evidence": [ { "id": "R-DME-1855210", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1855210" } ] }, { "id": "R-DME-1855211", "name": "I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-1629753" ], "output_participant_list": [], "enzyme_list": [ "Q9VP62-1", "Q7KTW5-1", "Q9VUW3-1", "Q9VUW1-1", "Q9VUW2-1", "Q9VUW4-1" ], "evidence": [ { "id": "R-DME-1855211", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1855211" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-1629731", "participant_name": "I3P [cytosol]", "crossref": [ { "id": "58401", "database": "ChEBI", "url": "" }, { "id": "ZINC000100028278", "database": "ZINC", "url": "" }, { "id": "C04006", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-1629753", "participant_name": "I4P [cytosol]", "crossref": [ { "id": "58469", "database": "ChEBI", "url": "" }, { "id": "ZINC000100016164", "database": "ZINC", "url": "" }, { "id": "C03546", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-870330", "participant_name": "I1P [cytosol]", "crossref": [ { "id": "58433", "database": "ChEBI", "url": "" }, { "id": "ZINC000100061358", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "Q7KTW5", "gene_name": "Dmel\\CG9391", "activity": [ { "ec_number": "3.1.3.25", "activity": "1D-myo-inositol 1-phosphate + H2O = myo-inositol + phosphate.", "evidence": [ { "id": "Q7KTW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7KTW5" } ] }, { "ec_number": "3.1.3.25", "activity": "", "evidence": [ { "id": "Q7KTW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7KTW5" } ] } ] }, { "uniprot_ac": "Q9VP62", "gene_name": "Dmel\\CG9389", "activity": [ { "ec_number": "3.1.3.25", "activity": "1D-myo-inositol 1-phosphate + H2O = myo-inositol + phosphate.", "evidence": [ { "id": "Q9VP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VP62" } ] }, { "ec_number": "3.1.3.25", "activity": "", "evidence": [ { "id": "Q9VP62", 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genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg 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Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VUX8", "url": "https://www.uniprot.org/uniprotkb/Q9VUX8" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VUX8", "url": 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perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VUX8", "url": "https://www.uniprot.org/uniprotkb/Q9VUX8" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VUX8", "url": "https://www.uniprot.org/uniprotkb/Q9VUX8" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { 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Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VV00", "url": "https://www.uniprot.org/uniprotkb/Q9VV00" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VV00", "url": "https://www.uniprot.org/uniprotkb/Q9VV00" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VV00", "url": "https://www.uniprot.org/uniprotkb/Q9VV00" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VV00", "url": "https://www.uniprot.org/uniprotkb/Q9VV00" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VV00", "url": "https://www.uniprot.org/uniprotkb/Q9VV00" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VV00", "url": "https://www.uniprot.org/uniprotkb/Q9VV00" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VV00", "url": "https://www.uniprot.org/uniprotkb/Q9VV00" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VV00", "url": "https://www.uniprot.org/uniprotkb/Q9VV00" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VV00", "url": "https://www.uniprot.org/uniprotkb/Q9VV00" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VV01-1", "url": "https://www.uniprot.org/uniprotkb/Q9VV01-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGTPHVCFADEQQQELQQQHRTASNGSLNNNNNKLDVGYNNTGGTPSPGGSLSVSPTPRYERNLGFFRQLSRRFGLRSQDDLVHSDDAASVATSRSGGGGCGGGVAGVTLQEEDAHSSSTDSCSSGRGLNAHQSRLELMSMSCASSETSSTLDIEEQQEQMQHQQAQQSKRKPISRASFSRLHRRSTSSLRRAFESLSLTSRSLSCSGPSPPPPLPPAGAQPAAALPLKSALKSASNVELHRQQQQQQKQPTGRSSSSCCGSASKNNKVKPPPQRILRQPVSYTYLKGMSGLPTQRVPRSSVCCQYARR", "length": 309, "header": "tr|Q9VV01-1|Q9VV01_DROME Isoform 1 of DUF4797 domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG13055 PE=4 SV=1 CANONICAL=Q9VV01-1" }, "isoforms": [ { "isoform_ac": "Q9VV01-1", "url": "https://www.uniprot.org/uniprotkb/Q9VV01/entry#Q9VV01-1", "sequence": { "sequence": 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Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VV01", "url": "https://www.uniprot.org/uniprotkb/Q9VV01" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VV01", "url": "https://www.uniprot.org/uniprotkb/Q9VV01" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VV01", "url": "https://www.uniprot.org/uniprotkb/Q9VV01" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VV01", "url": "https://www.uniprot.org/uniprotkb/Q9VV01" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VV01", "url": "https://www.uniprot.org/uniprotkb/Q9VV01" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VV01", "url": "https://www.uniprot.org/uniprotkb/Q9VV01" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VV01", "url": "https://www.uniprot.org/uniprotkb/Q9VV01" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VV01", "url": "https://www.uniprot.org/uniprotkb/Q9VV01" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VV01", "url": "https://www.uniprot.org/uniprotkb/Q9VV01" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"uniprot_canonical_ac": "Q9VV09-1", "uniprot_ac": "Q9VV09", "uniprot_id": "Q9VV09_DROME", "mass": { "chemical_mass": 65092.0, "monoisotopic_mass": 65092.0 }, "refseq": { "ac": "NP_001261934", "name": "uncharacterized protein, isoform C", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261934" }, "gene_names": [ { "name": "CT15890", "type": "recommended", "evidence": [ { "id": "Q9VV09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VV09" } ] }, { "name": "CG4950", "type": "synonym", "evidence": [ { "id": "NP_001261934", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261934" }, { "id": "Q9VV09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VV09" } ] }, { "name": "CT15890", "type": "synonym", "evidence": [ { "id": "NP_001261934", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261934" } ] }, { "name": "Dmel\\CG4950", "type": "synonym", "evidence": [ { "id": "NP_001261934", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261934" }, { "id": "Q9VV09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VV09" } ] }, { "name": "Dmel_CG4950", "type": "synonym", "evidence": [ { "id": "Q9VV09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VV09" } ] } ], "protein_names": [ { "name": "CG4950-PC", "type": "synonym", "evidence": [ { "id": "NP_001261934", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261934" } ] }, { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "Q9VV09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VV09/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein, isoform C", "type": "synonym", "evidence": [ { "id": "NP_001261934", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261934" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VV09", "url": "https://www.uniprot.org/uniprotkb/Q9VV09" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "CT15890", "url": "https://www.uniprot.org/uniprotkb/Q9VV09", "locus": { "chromosome": "3L", "start_pos": 16265797, "end_pos": 16268156, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0036587", "url": "https://www.ensemblgenomes.org/id/FBgn0036587" } ] } } ], "crossref": [ { "id": "FB:FBgn0036587", "url": "https://alliancegenome.org/gene/FB:FBgn0036587", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0036587", "url": "https://bgee.org/?page=gene&gene_id=FBgn0036587", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0036587", "url": "https://flybase.org/reports/FBgn0036587", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "39783", "url": "https://www.ncbi.nlm.nih.gov/gene/39783", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VV09", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VV09*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG4950", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG4950", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RSSIVFH", "url": "https://omabrowser.org/oma/group/RSSIVFH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VV09", "url": "https://www.orthodb.org/?gene=Q9VV09", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24366", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24366", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24366:SF96", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24366:SF96", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001261934", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261934", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VV09", "url": "https://www.uniprot.org/uniprotkb/Q9VV09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VV09-1", "url": "https://www.uniprot.org/uniprotkb/Q9VV09-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNRTRRILEVIVILILAISSCDGSGGDIPLRCDEYDSMGYMDVNEAFCTVTGFTVTHSQNVVIKNIPPGNMVKFMKFYESTLLYMPFHLFETFPYLKTLDVSNTNILELTRNAFSAASNLTYLNLAYNNLTSIQTSVFIGANVLMRLDLSYNEISSLSVNAFCGLHTISQIYLTGNLLKELHNDIFKDNEYLEKVSFEGNLLTSIQPEVFRNMRRIKEVNLSNNRLIFIHPDTFADAASLENLVLSYNELKNFQLTEKNIVHQLHLDNNYLTNLTINATRFVRASHNQISELFLHQSLHIETLDLSANKLSSISNITNITHMLYLDVSDNPIGPLNISTFSQLKRLRGLNLRGTGIRELKFGMFSKQKYLEELDLSFNNLTILNLDMFVPYLTNLKKFLIDGNGLTELQGNRTFSEAFPQLQKLGVSRNRFNCSYLHHLLIPPSLPESVVLNIEPDTNLDETPHIRDVSCISQSQEVVNASFTAEESKLESQIQMLSKQLDIVGSHSKNLELHLAFMQIFAYVMGGLVLVGVVSLITLRYLKNQRSGRYDRSSIVFRSNATMEANLTLGSEDLQ", "length": 574, "header": "tr|Q9VV09-1|Q9VV09_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=CT15890 PE=4 SV=2 CANONICAL=Q9VV09-1" }, "isoforms": [ { "isoform_ac": "Q9VV09-1", "url": "https://www.uniprot.org/uniprotkb/Q9VV09/entry#Q9VV09-1", "sequence": { "sequence": "MNRTRRILEVIVILILAISSCDGSGGDIPLRCDEYDSMGYMDVNEAFCTVTGFTVTHSQNVVIKNIPPGNMVKFMKFYESTLLYMPFHLFETFPYLKTLDVSNTNILELTRNAFSAASNLTYLNLAYNNLTSIQTSVFIGANVLMRLDLSYNEISSLSVNAFCGLHTISQIYLTGNLLKELHNDIFKDNEYLEKVSFEGNLLTSIQPEVFRNMRRIKEVNLSNNRLIFIHPDTFADAASLENLVLSYNELKNFQLTEKNIVHQLHLDNNYLTNLTINATRFVRASHNQISELFLHQSLHIETLDLSANKLSSISNITNITHMLYLDVSDNPIGPLNISTFSQLKRLRGLNLRGTGIRELKFGMFSKQKYLEELDLSFNNLTILNLDMFVPYLTNLKKFLIDGNGLTELQGNRTFSEAFPQLQKLGVSRNRFNCSYLHHLLIPPSLPESVVLNIEPDTNLDETPHIRDVSCISQSQEVVNASFTAEESKLESQIQMLSKQLDIVGSHSKNLELHLAFMQIFAYVMGGLVLVGVVSLITLRYLKNQRSGRYDRSSIVFRSNATMEANLTLGSEDLQ", "length": 574, "header": "tr|Q9VV09-1|Q9VV09_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=CT15890 PE=4 SV=2 CANONICAL=Q9VV09-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VV09", "url": "https://www.uniprot.org/uniprotkb/Q9VV09" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VV09", "url": "https://www.uniprot.org/uniprotkb/Q9VV09" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VV09", "url": "https://www.uniprot.org/uniprotkb/Q9VV09" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VV09", "url": "https://www.uniprot.org/uniprotkb/Q9VV09" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VV09", "url": "https://www.uniprot.org/uniprotkb/Q9VV09" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VV09", "url": "https://www.uniprot.org/uniprotkb/Q9VV09" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VV09", "url": "https://www.uniprot.org/uniprotkb/Q9VV09" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VV09", "url": "https://www.uniprot.org/uniprotkb/Q9VV09" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VV09", "url": "https://www.uniprot.org/uniprotkb/Q9VV09" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VV09", "url": "https://www.uniprot.org/uniprotkb/Q9VV09" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VV09", "url": "https://www.uniprot.org/uniprotkb/Q9VV09" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG4950", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG4950", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZVD5-1", "protein_name": "Transforming growth factor beta activator LRRC32", "gene_name": "Lrrc32", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSYQILILLAMLTLGLAISQRRDQVPCRTVNKEALCHGLSLLQVPSVLSLDIQALYLSGNRLQSILVSPLSFYTALRHLDLSDNEISFLQPGVFQALPYLEHLNLAHNRLAAGMALNSGGLGRLPLVVSLDLSGNSLHGSLVERLLGEAPRLRTLSLAENSLTRLARHTFWGMPAMEQLDLHSNVLMDIEDGAFEALPQLTHLNLSRNSLTCISDFSLQQLQVLDLSCNSIETFQTAPESQAQFQLAWLDLRENKLLHFPDLAMFPRLIYLNVSNNLIQLPTGLPQDSEDLHAPSEGWSASLLSNPSRNASIHPLSQLLNLDLSYNEIELVPAGFLEHLTSLRFLNLSRNCLRSFEARRAGSLPCLVLLDLSHNVLEALELGTKVLGSLKTLLLQDNTLRELPPYTFAGLASLQRLNLQGNQVSPCGGQAEPGPPGCVDFSGIPTLHFLNMAGNSMETLRAGSFLHTPLTELDLSANPGLDVATGALVGLEASLEVLELQGNGLVVLRVDLPCFRRLKRLNLAENRLSHLPAWTRAVSLEVLDLRNNSFSLLPGNAMGGLETSLRRLYLQGNPLSCCGNGWLAAQLHQGRVDVDATQDLICRFGSQEEVSLSLVRPEDCEKGGLKNVNLIIILSFTLVSAIVLTTLATCCFLRRQKLSQQYKA", "length": 663 }, "evidence": [ { "id": "RGD:1309087", "url": "https://alliancegenome.org/gene/RGD:1309087#orthology", "database": "AGR" }, { "id": "FB:FBgn0036587", "url": "https://alliancegenome.org/gene/FB:FBgn0036587#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3XA59-1", "protein_name": "Transforming growth factor beta activator LRRC32", "gene_name": "Lrrc32", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSHQILLLLAMLTLGLAISQRREQVPCRTVNKEALCHGLGLLQVPSVLSLDIQALYLSGNQLQSILVSPLGFYTALRHLDLSDNQISFLQAGVFQALPYLEHLNLAHNRLATGMALNSGGLGRLPLLVSLDLSGNSLHGNLVERLLGETPRLRTLSLAENSLTRLARHTFWGMPAVEQLDLHSNVLMDIEDGAFEALPHLTHLNLSRNSLTCISDFSLQQLQVLDLSCNSIEAFQTAPEPQAQFQLAWLDLRENKLLHFPDLAVFPRLIYLNVSNNLIQLPAGLPRGSEDLHAPSEGWSASPLSNPSRNASTHPLSQLLNLDLSYNEIELVPASFLEHLTSLRFLNLSRNCLRSFEARQVDSLPCLVLLDLSHNVLEALELGTKVLGSLQTLLLQDNALQELPPYTFASLASLQRLNLQGNQVSPCGGPAEPGPPGCVDFSGIPTLHVLNMAGNSMGMLRAGSFLHTPLTELDLSTNPGLDVATGALVGLEASLEVLELQGNGLTVLRVDLPCFLRLKRLNLAENQLSHLPAWTRAVSLEVLDLRNNSFSLLPGNAMGGLETSLRRLYLQGNPLSCCGNGWLAAQLHQGRVDVDATQDLICRFGSQEELSLSLVRPEDCEKGGLKNVNLILLLSFTLVSAIVLTTLATICFLRRQKLSQQYKA", "length": 663 }, "evidence": [ { "id": "RGD:1309087", "url": "https://alliancegenome.org/gene/RGD:1309087#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q0KHN6-1", "protein_name": "Chaoptin", "gene_name": "CG40500", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MCRGRNLRTSAALVNLLAKCTKSTNGQAAVLAKDKESENRENLVPQKQRAQRQNKQQQHPQQYPQMMQQQQQQQQQQRQEQHQEQHNQRQQQGRQIEQMAMGTNAEAAAAKKHKHQTKPTDSECEGKHKHKRNRNNVAGVQQHVLRLKLELQLLLCALLPTALLLGLLPLPPGAAATAMISSAKGSVRELLLTEMGGGGVGVGVGGSSGGAAHPAGGGPGTGLAGGDGGGAAGIECPSFDNTACPCYKFEDGLFLECPGTTAISLRSTLERISAPIHSLSIYDFDRSVTSLSQDVFQPGVHIRHLQFSHSHLEALKDNSLRNVRSSLESLSIVNGKLTQMPSRALSSMQKLTALDFDYNEIVRVDDYSFYGLRISKLNMKGNRLQGMPEHAFAGLEECMQEIDVSENGLRTFPLMALRKLDHLRILRLSNNRIPTFYGDIQLATNNASAAAAAVGAFQLPSLIFLDLSSNQFAEIGPDCFRAFPQLKTLSFYANQIELVQPEAFKSLRELMSLDMSHNRIIGLDPKVFEKNKRLQTVDLSHNHIHTIGGVFSNLPQLREVFLSENNILELPADAFTNSTNVDVIYLESNAIAHIDPNVFSTLVNLDHLYLRSNFIPLLPVTLFDKSTKLTSLSLDNNEIQDLEIGMFRKLEHLREVRLHNNRIRRVRRGVFEPLPSLQELHIQKNSIEDIEPQAFHTLENMQHINLQDNQLTVLEDIFPDENSSLLSVQLEANYLHKVHPRTFSRQQKVQIMWLKDNQLTRVERSFFADTPQLGRLYLSDNKIRDIEKDTFVNLLLLQFLDLSGNQLRQLRRDYFAPLQDLEELSLARNHIEAIEGYAFAKLKNLKSLDLSHNPLVQLTRDIFSNEFPLNSLNLGNCSLRKLEQHAFKSLTNLNELNLERNQLNPADIQTLDIPNLRRLLLSHNNFSYAGSVGIMAGMLDRLRSLQQLSMSNCSLGQIPDLLFAKNTNLVRLDLCDNRLTQINRNIFSGLNVFKELRLCRNELSDFPHIALYNLSTLESLDLARNQLASIDFFKLSGTLNLRQLILRDNKITALSGFNAVNLTQLDSVDLSGNLLLSLPANFLRHSINLQKVHLSNNRFLQIPSSALSDVSIPRLSWLNLTGNPINRIYTVKEERYPYLKELYICQTNLSILTSKDFEAFQALQHLHLVNNRITRISPGAFKSLTNLLTLDLSVNELEMLPKERLQGLRLLRFLNISHNTLKDLEEFSVDLLEMQTLDLSFNQLDRISKKTFRNLHGLLELFLMGNRMTVLSNDAFRFLRKLHVLDLRKNYFELVPLEPLRPLETNLRTLRLEENPLHCSCDAQKLWEWLRDHRKWSLSMGSGAGRGIGGLTGGLGGDSINYLRCEHPTELRGKVFGRMEPQQFCDAPLIPKMAIQDIQPYSVVVSWQSRDHLGLNGFEIVYHATGDGLVTAGSPTSRERDSLRDIHDPERQRTRDQARERSRERDRDRERDRERFSIATDEIHGKRLNGTASSTKLTKLSPNTRYHICVIGSGNWLSEPLANALQRLHTNESLREEEAVMMSAPLPESFSPYQHQHNRNSNGNANPAMVQDHNKKQNPDQDLDNVVGQDNALMEVLKNSHISACTDVQTLDSTPSLVTDENGLSSNGFIHSILTRRLGLIVGCCLGIIVFIVMISVLSYVKLKKKRIENAKRQAALPPEYISYRHFSIPNEELTRTAANAGTVAAAAAANNSHNSNNSTDEGSSPHMSSVPSGISAHISGTSLSTGGTGTGSTTTTATTPIGGVPLGKAGSTLVGVGLVVADSSVDVGYAHNHAHAHAHRHMAAGVVLNTNHLSVC", "length": 1817 }, "evidence": [ { "id": "RGD:1310771", "url": "https://alliancegenome.org/gene/RGD:1310771#orthology", "database": "AGR" }, { "id": "HGNC:24613", "url": "https://alliancegenome.org/gene/HGNC:24613#orthology", "database": "AGR" }, { "id": "MGI:2445095", "url": "https://alliancegenome.org/gene/MGI:2445095#orthology", "database": "AGR" }, { "id": "RGD:1309087", "url": "https://alliancegenome.org/gene/RGD:1309087#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q14392-1", "protein_name": "Transforming growth factor beta activator LRRC32", "gene_name": "LRRC32", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRPQILLLLALLTLGLAAQHQDKVPCKMVDKKVSCQVLGLLQVPSVLPPDTETLDLSGNQLRSILASPLGFYTALRHLDLSTNEISFLQPGAFQALTHLEHLSLAHNRLAMATALSAGGLGPLPRVTSLDLSGNSLYSGLLERLLGEAPSLHTLSLAENSLTRLTRHTFRDMPALEQLDLHSNVLMDIEDGAFEGLPRLTHLNLSRNSLTCISDFSLQQLRVLDLSCNSIEAFQTASQPQAEFQLTWLDLRENKLLHFPDLAALPRLIYLNLSNNLIRLPTGPPQDSKGIHAPSEGWSALPLSAPSGNASGRPLSQLLNLDLSYNEIELIPDSFLEHLTSLCFLNLSRNCLRTFEARRLGSLPCLMLLDLSHNALETLELGARALGSLRTLLLQGNALRDLPPYTFANLASLQRLNLQGNRVSPCGGPDEPGPSGCVAFSGITSLRSLSLVDNEIELLRAGAFLHTPLTELDLSSNPGLEVATGALGGLEASLEVLALQGNGLMVLQVDLPCFICLKRLNLAENRLSHLPAWTQAVSLEVLDLRNNSFSLLPGSAMGGLETSLRRLYLQGNPLSCCGNGWLAAQLHQGRVDVDATQDLICRFSSQEEVSLSHVRPEDCEKGGLKNINLIIILTFILVSAILLTTLAACCCVRRQKFNQQYKA", "length": 662 }, "evidence": [ { "id": "RGD:1309087", "url": "https://alliancegenome.org/gene/RGD:1309087#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5BK65-1", "protein_name": "Transforming growth factor beta activator LRRC33", "gene_name": "Nrros", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEFLPLWLCLGFHFLIVEWRSGRGTATAASQGGCKVVDRVADCRSLNLASVPSGLPAHSRMLVLDANPLRVLWNHSLQAYPRLEDLSLHSCHLDRISHWAFHEQGHLQNLVLADNRLSENYKESATALHTLLRLRRLDLSGNSLTEDMAALMLQNLSSLEVVSLARNTLMRLDDSVFEGLERLVELDLQRNYIFEIEGGAFDGLTELRRLNLAYNNLPCIVDFSLTQLRFLNVSYNILEWFLAAREEAAFELEILDLSHNQLLFFPLLPQCGKLHTLLLQDNSMGFYRELYNTSSPQEMVAQFLLVDGNVTNITTVSLWEEFSSSDLSALRFLDMSQNQLRHLPDGFLKKTPSLSHLNLNQNCLTKLHIREHEPPGALTELDLSRNQLAELHLAPGLTGSLKNLRVFNLSSNQLLGVPTGLFHSASSITTLDMSHNQISLCPQTVPLDWEEPSSCVDFRNMASLRSLSLDGCGLKALQDCPFQGTSLTHLDLSSNWGILNGSVSPLSAVAPTLQVLSLRNVGLGSGAAEMDFSGFGNLRELDLSGNSLTSFPKFKGSSALQTLDLRRNSLTALPQRVVSEQPLRGLQTIYLSQNPYDCCGVEGWGALQHFKTIADLSMVTCNLSSKIIRVVELPEGIPQDCKWGQVDTGLFYLVLILPSCLTLLVASTVIFLTFKKPLLQVIKSRCHWSSIY", "length": 692 }, "evidence": [ { "id": "RGD:1310771", "url": "https://alliancegenome.org/gene/RGD:1310771#orthology", "database": "AGR" }, { "id": "HGNC:24613", "url": "https://alliancegenome.org/gene/HGNC:24613#orthology", "database": "AGR" }, { "id": "MGI:2445095", "url": "https://alliancegenome.org/gene/MGI:2445095#orthology", "database": "AGR" }, { "id": "FB:FBgn0036587", "url": "https://alliancegenome.org/gene/FB:FBgn0036587#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6AXL3-1", "protein_name": "Transforming growth factor beta activator LRRC33", "gene_name": "nrros", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPVCGCLSVVLSHAVVLLMLVLHSASGHPQTFPCRLIQRVALCSGRQLSVIPDCLPHETEEIFFDRNLLENLQDGLSRYPFLRMFSCANNQLMTVAETAFIESHLLENLNLANNELHHGHKQVAQAFRSLTQLKTLDLSGNGLSEDMVSVLVANLSSLESLYLSRNGMQRLDESTFRDLHQLKELNVERNLLFEISGAFDHMKKLQRLNLAFNCLPCLVNFEMTQLLVLNASHNSIEWFITNQNLTETFQLETLDLSDNHLLFFPFLPTNNQIRTLLLSNNRVGFYQHLANSTSSNWTTSVDYYNLGQNISNITMDLWNENLHGNLSSVEFLDLSENKVNYFPQGFIKQMPQLYWLKLRSNCLQSFSLTSEDLPVTIYELDVSRNRLTEIKASQTSKNKLNNLTHLNLSTNDLQNFPPMIFTSLPNLNTLDLSHNTVDVCYSSNYMGLSGCVEWSSMASLKQLYLADCSIQNVPSSAFKGTSLTHLELSNNPNLHLKQQSLKGLANTLQHLGIGNTGLQDFDFSPYTNLKSLNISRNSLSKLPDSLMALNLKLLDLRDNSLTTIKSEHASLLAKKLQTVYMNGNAFNCCHLDWFRTFGENKGIHVADLSEITCLDLNYRRHKVVLTDAVYCGFTNNNKESVVWYILLFVTVSVSIMGISVIYMLTFKPRMLPRVIKKKCWRPTSY", "length": 685 }, "evidence": [ { "id": "RGD:1310771", "url": "https://alliancegenome.org/gene/RGD:1310771#orthology", "database": "AGR" }, { "id": "HGNC:24613", "url": "https://alliancegenome.org/gene/HGNC:24613#orthology", "database": "AGR" }, { "id": "MGI:2445095", "url": "https://alliancegenome.org/gene/MGI:2445095#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q86YC3-1", "protein_name": "Transforming growth factor beta activator LRRC33", "gene_name": "NRROS", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MELLPLWLCLGFHFLTVGWRNRSGTATAASQGVCKLVGGAADCRGQSLASVPSSLPPHARMLTLDANPLKTLWNHSLQPYPLLESLSLHSCHLERISRGAFQEQGHLRSLVLGDNCLSENYEETAAALHALPGLRRLDLSGNALTEDMAALMLQNLSSLRSVSLAGNTIMRLDDSVFEGLERLRELDLQRNYIFEIEGGAFDGLAELRHLNLAFNNLPCIVDFGLTRLRVLNVSYNVLEWFLATGGEAAFELETLDLSHNQLLFFPLLPQYSKLRTLLLRDNNMGFYRDLYNTSSPREMVAQFLLVDGNVTNITTVSLWEEFSSSDLADLRFLDMSQNQFQYLPDGFLRKMPSLSHLNLHQNCLMTLHIREHEPPGALTELDLSHNQLSELHLAPGLASCLGSLRLFNLSSNQLLGVPPGLFANARNITTLDMSHNQISLCPLPAASDRVGPPSCVDFRNMASLRSLSLEGCGLGALPDCPFQGTSLTYLDLSSNWGVLNGSLAPLQDVAPMLQVLSLRNMGLHSSFMALDFSGFGNLRDLDLSGNCLTTFPRFGGSLALETLDLRRNSLTALPQKAVSEQLSRGLRTIYLSQNPYDCCGVDGWGALQHGQTVADWAMVTCNLSSKIIRVTELPGGVPRDCKWERLDLGLLYLVLILPSCLTLLVACTVIVLTFKKPLLQVIKSRCHWSSVY", "length": 692 }, "evidence": [ { "id": "RGD:1310771", "url": "https://alliancegenome.org/gene/RGD:1310771#orthology", "database": "AGR" }, { "id": "HGNC:24613", "url": "https://alliancegenome.org/gene/HGNC:24613#orthology", "database": "AGR" }, { "id": "MGI:2445095", "url": "https://alliancegenome.org/gene/MGI:2445095#orthology", "database": "AGR" }, { "id": "FB:FBgn0036587", "url": "https://alliancegenome.org/gene/FB:FBgn0036587#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BMT4-1", "protein_name": "Transforming growth factor beta activator LRRC33", "gene_name": "Nrros", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEFPPLWLCLGFHFLIVEWRSGPGTATAASQGGCKVVDGVADCRGLNLASVPSSLPPHSRMLILDANPLKDLWNHSLQAYPRLENLSLHSCHLDRISHYAFREQGHLRNLVLADNRLSENYKESAAALHTLLGLRRLDLSGNSLTEDMAALMLQNLSSLEVVSLARNTLMRLDDSIFEGLEHLVELDLQRNYIFEIEGGAFDGLTELRRLNLAYNNLPCIVDFSLTQLRFLNVSYNILEWFLAAREEVAFELEILDLSHNQLLFFPLLPQCGKLHTLLLQDNNMGFYRELYNTSSPQEMVAQFLLVDGNVTNITTVNLWEEFSSSDLSALRFLDMSQNQFRHLPDGFLKKTPSLSHLNLNQNCLKMLHIREHEPPGALTELDLSHNQLAELHLAPGLTGSLRNLRVFNLSSNQLLGVPTGLFDNASSITTIDMSHNQISLCPQMVPVDWEGPPSCVDFRNMGSLRSLSLDGCGLKALQDCPFQGTSLTHLDLSSNWGVLNGSISPLWAVAPTLQVLSLRDVGLGSGAAEMDFSAFGNLRALDLSGNSLTSFPKFKGSLALRTLDLRRNSLTALPQRVVSEQPLRGLQTIYLSQNPYDCCGVEGWGALQQHFKTVADLSMVTCNLSSKIVRVVELPEGLPQGCKWEQVDTGLFYLVLILPSCLTLLVACTVVFLTFKKPLLQVIKSRCHWSSIY", "length": 693 }, "evidence": [ { "id": "RGD:1310771", "url": "https://alliancegenome.org/gene/RGD:1310771#orthology", "database": "AGR" }, { "id": "HGNC:24613", "url": "https://alliancegenome.org/gene/HGNC:24613#orthology", "database": "AGR" }, { "id": "MGI:2445095", "url": "https://alliancegenome.org/gene/MGI:2445095#orthology", "database": "AGR" }, { "id": "FB:FBgn0036587", "url": "https://alliancegenome.org/gene/FB:FBgn0036587#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 119, "end_pos": 121, "annotation": "n_glycosylation_sequon" }, { "start_pos": 129, "end_pos": 131, "annotation": "n_glycosylation_sequon" }, { "start_pos": 220, "end_pos": 222, "annotation": "n_glycosylation_sequon" }, { "start_pos": 273, "end_pos": 275, "annotation": "n_glycosylation_sequon" }, { "start_pos": 277, "end_pos": 279, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2, "end_pos": 4, "annotation": "n_glycosylation_sequon" }, { "start_pos": 315, "end_pos": 317, "annotation": "n_glycosylation_sequon" }, { "start_pos": 318, "end_pos": 320, "annotation": "n_glycosylation_sequon" }, { "start_pos": 336, "end_pos": 338, "annotation": "n_glycosylation_sequon" }, { "start_pos": 379, "end_pos": 381, "annotation": "n_glycosylation_sequon" }, { "start_pos": 411, "end_pos": 413, "annotation": "n_glycosylation_sequon" }, { "start_pos": 432, "end_pos": 434, "annotation": "n_glycosylation_sequon" }, { "start_pos": 479, "end_pos": 481, "annotation": "n_glycosylation_sequon" }, { "start_pos": 559, "end_pos": 561, "annotation": "n_glycosylation_sequon" }, { "start_pos": 565, "end_pos": 567, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 119, "end_pos": 121 }, { "start_pos": 129, "end_pos": 131 }, { "start_pos": 220, "end_pos": 222 }, { "start_pos": 273, "end_pos": 275 }, { "start_pos": 277, "end_pos": 279 }, { "start_pos": 2, "end_pos": 4 }, { "start_pos": 315, "end_pos": 317 }, { "start_pos": 318, "end_pos": 320 }, { "start_pos": 336, "end_pos": 338 }, { "start_pos": 379, "end_pos": 381 }, { "start_pos": 411, "end_pos": 413 }, { "start_pos": 432, "end_pos": 434 }, { "start_pos": 479, "end_pos": 481 }, { "start_pos": 559, "end_pos": 561 }, { "start_pos": 565, "end_pos": 567 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { 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"https://www.ncbi.nlm.nih.gov/protein/NP_648857" }, "gene_names": [ { "name": "anon-WO0153538.46", "type": "recommended", "evidence": [ { "id": "Q9VV11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VV11" } ] }, { "name": "CG13067", "type": "synonym", "evidence": [ { "id": "NP_648857", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648857" }, { "id": "Q9VV11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VV11" } ] }, { "name": "Dmel\\CG13067", "type": "synonym", "evidence": [ { "id": "NP_648857", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648857" }, { "id": "Q9VV11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VV11" } ] }, { "name": "Dmel_CG13067", "type": "synonym", "evidence": [ { "id": "Q9VV11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VV11" } ] }, { "name": "anon-WO0153538.39", "type": "synonym", "evidence": [ { "id": "NP_648857", 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"https://www.uniprot.org/uniprotkb/Q9VV21" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG4962", "url": "https://www.uniprot.org/uniprotkb/Q9VV21", "locus": { "chromosome": "3L", "start_pos": 16294711, "end_pos": 16295547, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0036597", "url": "https://www.ensemblgenomes.org/id/FBgn0036597" } ] } } ], "crossref": [ { "id": "FB:FBgn0036597", "url": "https://alliancegenome.org/gene/FB:FBgn0036597", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0036597", "url": "https://bgee.org/?page=gene&gene_id=FBgn0036597", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0036597", "url": "https://flybase.org/reports/FBgn0036597", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "39793", "url": "https://www.ncbi.nlm.nih.gov/gene/39793", "database": "GeneID", 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SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VV21", "url": "https://www.uniprot.org/uniprotkb/Q9VV21" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VV21", "url": "https://www.uniprot.org/uniprotkb/Q9VV21" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VV21", "url": "https://www.uniprot.org/uniprotkb/Q9VV21" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VV21", "url": "https://www.uniprot.org/uniprotkb/Q9VV21" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VV21", "url": "https://www.uniprot.org/uniprotkb/Q9VV21" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VV21", "url": "https://www.uniprot.org/uniprotkb/Q9VV21" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VV21", "url": "https://www.uniprot.org/uniprotkb/Q9VV21" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VV21", "url": "https://www.uniprot.org/uniprotkb/Q9VV21" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VV21", "url": "https://www.uniprot.org/uniprotkb/Q9VV21" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VV21", "url": "https://www.uniprot.org/uniprotkb/Q9VV21" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VV21", "url": "https://www.uniprot.org/uniprotkb/Q9VV21" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], 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inflammatory bowel disease in which the cause of the disease is a mutation in the NOD2 gene." }, { "id": "MONDO:0009960", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009960", "name": "Crohn disease-associated growth failure", "description": "" }, { "id": "MONDO:0009960", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009960", "name": "IBD1", "description": "" }, { "id": "MONDO:0009960", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009960", "name": "NOD2 inflammatory bowel disease", "description": "" }, { "id": "MONDO:0009960", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009960", "name": "inflammatory bowel disease (Crohn disease) 1", "description": "" }, { "id": "MONDO:0009960", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009960", "name": "inflammatory bowel disease 1", "description": "" }, { "id": "MONDO:0009960", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009960", "name": "inflammatory bowel disease 1, Crohn disease", "description": "" }, { "id": "MONDO:0009960", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009960", "name": "inflammatory bowel disease caused by mutation in NOD2", "description": "" }, { "id": "MONDO:0009960", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009960", "name": "inflammatory bowel disease type 1", "description": "" }, { "id": "MONDO:0009960", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009960", "name": "paediatric ulcerative colitis", "description": "" }, { "id": "MONDO:0009960", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009960", "name": "pediatric ulcerative colitis", "description": "" }, { "id": "MONDO:0009960", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009960", "name": "ulcerative colitis, paediatric", "description": "" }, { "id": "MONDO:0009960", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009960", "name": "ulcerative colitis, pediatric", "description": "" }, { "id": "MIM:266600", "resource": "MIM", "url": "https://www.omim.org/entry/266600", "name": "Inflammatory bowel disease 1", "description": "Inflammatory bowel disease 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "0050589", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050589" } ] }, { "disease_id": "DOID:14283", "recommended_name": { "id": "DOID:14283", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14283", "name": "primary hypertrophic osteoarthropathy", "description": "" }, "synonyms": [ { "id": "DOID:14283", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14283", "name": "Pachydermoperiostosis of nail", "description": "" }, { "id": "DOID:14283", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14283", "name": "Pachydermoperiostosis syndrome", "description": "" }, { "id": "MONDO:0024546", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024546", "name": "hypertrophic osteoarthropathy, primary, autosomal recessive, 1", "description": "Any primary hypertrophic osteoarthropathy in which the cause of the disease is a mutation in the HPGD gene." }, { "id": "MONDO:0024546", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024546", "name": "HPGD primary hypertrophic osteoarthropathy", "description": "" }, { "id": "MONDO:0024546", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024546", "name": "hypertrophic osteoarthropathy, primary, autosomal recessive 1", "description": "" }, { "id": "MONDO:0024546", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024546", "name": "hypertrophic osteoarthropathy, primary, autosomal recessive, 1", "description": "" }, { "id": "MONDO:0024546", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024546", "name": "primary hypertrophic osteoarthropathy caused by mutation in HPGD", "description": "" }, { "id": "MONDO:0024546", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024546", "name": "PHOAR1", "description": "" }, { "id": "MIM:259100", "resource": "MIM", "url": "https://www.omim.org/entry/259100", "name": "Cranioosteoarthropathy", "description": "Cranioosteoarthropathy" } ], "unlinked_id_list": [], "evidence": [ { "id": "14283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14283" } ] }, { "disease_id": "DOID:1520", "recommended_name": { "id": "DOID:1520", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1520", "name": "colon carcinoma", "description": "A colon cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells." }, "synonyms": [ { "id": "DOID:1520", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1520", "name": "Colonic carcinoma", "description": "" }, { "id": "DOID:1520", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1520", "name": "carcinoma of colon", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "1520", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1520" } ] }, { "disease_id": "DOID:305", "recommended_name": { "id": "DOID:305", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:305", "name": "carcinoma", "description": "A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells." }, "synonyms": [ { "id": "DOID:305", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:305", "name": "epithelial cancer", "description": "" }, { "id": "DOID:305", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:305", "name": "epithelioma", "description": "" }, { "id": "DOID:305", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:305", "name": "malignant Epithelioma", "description": "" } ], "unlinked_id_list": [ "DOID:0080524", "DOID:0080525", "DOID:1542", "DOID:3112", "DOID:3973", "DOID:4455", "DOID:4931", "DOID:5662", "DOID:2599", "DOID:1294", "DOID:2151", "DOID:4015", "DOID:3149", "DOID:4907", "DOID:3451" ], "evidence": [ { "id": "305", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:305" } ] }, { "disease_id": "DOID:5394", "recommended_name": { "id": "DOID:5394", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5394", "name": "prolactinoma", "description": "" }, "synonyms": [ { "id": "DOID:5394", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5394", "name": "PITUITARY ADENOMA, PROLACTIN-SECRETING", "description": "" }, { "id": "DOID:5394", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5394", "name": "Prolactinoma of Pituitary gland", "description": "" }, { "id": "DOID:5394", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5394", "name": "familial prolactinoma", "description": "" }, { "id": "MONDO:0010911", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010911", "name": "prolactin-producing pituitary gland adenoma", "description": "Prolactinoma is a usually benign neoplasm of the pituitary gland that results in hyperprolactinemia. The most common clinical manifestations are amenorrhea and infertility in women; and impotence, decreased libido and infertility in men." }, { "id": "MONDO:0010911", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010911", "name": "PRL producing pituitary gland adenoma", "description": "" }, { "id": "MONDO:0010911", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010911", "name": "PRL-secreting pituitary adenoma", "description": "" }, { "id": "MONDO:0010911", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010911", "name": "PRLoma", "description": "" }, { "id": "MONDO:0010911", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010911", "name": "lactotrope adenoma", "description": "" }, { "id": "MONDO:0010911", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010911", "name": "lactotroph adenoma", "description": "" }, { "id": "MONDO:0010911", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010911", "name": "lactotroph cell adenoma", "description": "" }, { "id": "MONDO:0010911", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010911", "name": "pituitary gland prolactinoma", "description": "" }, { "id": "MONDO:0010911", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010911", "name": "pituitary lactotrophic adenoma", "description": "" }, { "id": "MONDO:0010911", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010911", "name": "pituitary prolactinoma", "description": "" }, { "id": "MONDO:0010911", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010911", "name": "prolactin producing adenoma of pituitary", "description": "" }, { "id": "MONDO:0010911", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010911", "name": "prolactin producing adenoma of pituitary gland", "description": "" }, { "id": "MONDO:0010911", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010911", "name": "prolactin producing adenoma of the pituitary", "description": "" }, { "id": "MONDO:0010911", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010911", "name": "prolactin producing adenoma of the pituitary gland", "description": "" }, { "id": "MONDO:0010911", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010911", "name": "prolactin producing pituitary adenoma", "description": "" }, { "id": "MONDO:0010911", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010911", "name": "prolactin producing pituitary gland adenoma", "description": "" }, { "id": "MONDO:0010911", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010911", "name": "prolactin secreting adenoma", "description": "" }, { "id": "MONDO:0010911", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010911", "name": "prolactin secreting adenoma of pituitary", "description": "" }, { "id": "MONDO:0010911", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010911", "name": "prolactin secreting adenoma of pituitary gland", "description": "" }, { "id": "MONDO:0010911", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010911", "name": "prolactin secreting adenoma of the pituitary", "description": "" }, { "id": "MONDO:0010911", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010911", "name": "prolactin secreting adenoma of the pituitary gland", "description": "" }, { "id": "MONDO:0010911", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010911", "name": "prolactin secreting pituitary adenoma", "description": "" }, { "id": "MONDO:0010911", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010911", "name": "prolactin 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adenoma of the Pituitary", "description": "" }, { "id": "DOID:6255", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:6255", "name": "Somatotroph adenoma", "description": "" }, { "id": "DOID:6255", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:6255", "name": "growth hormone secreting adenoma of pituitary", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "6255", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6255" } ] }, { "disease_id": "DOID:6432", "recommended_name": { "id": "DOID:6432", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:6432", "name": "pulmonary hypertension", "description": "A hypertension characterized by an increase of blood pressure in the pulmonary artery, pulmonary vein or pulmonary capillaries." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "6432", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6432" } ] }, { "disease_id": "DOID:750", "recommended_name": { "id": "DOID:750", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:750", "name": "peptic ulcer disease", "description": "" }, "synonyms": [ { "id": "DOID:750", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:750", "name": "acute peptic ulcer with hemorrhage", "description": "" }, { "id": "DOID:750", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:750", "name": "acute peptic ulcer with hemorrhage and perforation", "description": "" }, { "id": "DOID:750", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:750", "name": "acute peptic ulcer without hemorrhage and without perforation", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "750", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:750" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VV47", "url": "https://www.uniprot.org/uniprotkb/Q9VV47" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG4842", "url": "https://www.uniprot.org/uniprotkb/Q9VV47", "locus": { "chromosome": "3L", "start_pos": 16369518, "end_pos": 16368389, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0036620", "url": "https://www.ensemblgenomes.org/id/FBgn0036620" } ] } } ], "crossref": [ { "id": "FB:FBgn0036620", "url": "https://alliancegenome.org/gene/FB:FBgn0036620", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0036620", "url": "https://bgee.org/?page=gene&gene_id=FBgn0036620", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0036620", "url": "https://flybase.org/reports/FBgn0036620", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "39817", "url": "https://www.ncbi.nlm.nih.gov/gene/39817", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002426", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002426", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020904", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020904", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG4842", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG4842", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MANPIYF", "url": "https://omabrowser.org/oma/group/MANPIYF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VV47", "url": "https://www.orthodb.org/?gene=Q9VV47", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44229", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44229", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44229:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44229:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00106", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00106", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-2142700", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-2142700", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-9018676", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9018676", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-9018896", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9018896", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_648885", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648885", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VV47", "url": "https://www.uniprot.org/uniprotkb/Q9VV47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VV47-1", "url": "https://www.uniprot.org/uniprotkb/Q9VV47-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDLAGKNVVYLGGFGGIGQKCVQELLQRPIKALAIFDLNANEQLLAKWKSQHPDTDVFYHKLDITQKSDIDAAYKATAERFGHFDVVVNGSGLMNDRLVELTIQINLLGVINSTLTALEYMDKAKGGKGGLIVNISSVAGLQPTAIMAIYSAAKTGVTTFTRAMANPYFYAHSGVGFLTICPGFTDTGLLEDIGNKTTFTYDTPMLAMFNRVKRQKAEDCARNLVSAIETSKNGTVLMLEMGETTEVDMPVMWKPQLDN", "length": 259, "header": "tr|Q9VV47-1|Q9VV47_DROME Isoform 1 of Fat body protein 2 OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG4842 PE=1 SV=2 CANONICAL=Q9VV47-1" }, "isoforms": [ { "isoform_ac": "Q9VV47-1", "url": "https://www.uniprot.org/uniprotkb/Q9VV47/entry#Q9VV47-1", "sequence": { "sequence": "MDLAGKNVVYLGGFGGIGQKCVQELLQRPIKALAIFDLNANEQLLAKWKSQHPDTDVFYHKLDITQKSDIDAAYKATAERFGHFDVVVNGSGLMNDRLVELTIQINLLGVINSTLTALEYMDKAKGGKGGLIVNISSVAGLQPTAIMAIYSAAKTGVTTFTRAMANPYFYAHSGVGFLTICPGFTDTGLLEDIGNKTTFTYDTPMLAMFNRVKRQKAEDCARNLVSAIETSKNGTVLMLEMGETTEVDMPVMWKPQLDN", "length": 259, "header": "tr|Q9VV47-1|Q9VV47_DROME Isoform 1 of Fat body protein 2 OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG4842 PE=1 SV=2 CANONICAL=Q9VV47-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VV47", "url": "https://www.uniprot.org/uniprotkb/Q9VV47" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VV47", "url": "https://www.uniprot.org/uniprotkb/Q9VV47" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VV47", "url": "https://www.uniprot.org/uniprotkb/Q9VV47" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VV47", "url": "https://www.uniprot.org/uniprotkb/Q9VV47" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VV47", "url": "https://www.uniprot.org/uniprotkb/Q9VV47" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VV47", "url": "https://www.uniprot.org/uniprotkb/Q9VV47" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VV47", "url": "https://www.uniprot.org/uniprotkb/Q9VV47" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VV47", "url": "https://www.uniprot.org/uniprotkb/Q9VV47" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VV47", "url": "https://www.uniprot.org/uniprotkb/Q9VV47" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VV47", "url": "https://www.uniprot.org/uniprotkb/Q9VV47" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VV47", "url": "https://www.uniprot.org/uniprotkb/Q9VV47" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG4842", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG4842", "resource": "KEGG Pathway" }, { "id": "R-DME-2142700", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-2142700", "resource": "Reactome", "description": "Biosynthesis of Lipoxins (LX)" }, { "id": "R-DME-9018676", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9018676", "resource": "Reactome", "description": "Biosynthesis of D-series resolvins" }, { "id": "R-DME-9018896", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9018896", "resource": "Reactome", "description": "Biosynthesis of E-series 18(S)-resolvins" } ], "orthologs": [ { "uniprot_canonical_ac": "E7F258-1", "protein_name": "15-hydroxyprostaglandin dehydrogenase [NAD(+)]", "gene_name": "hpgd", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": 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"https://alliancegenome.org/gene/HGNC:5154#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8VCC1-1", "protein_name": "15-hydroxyprostaglandin dehydrogenase [NAD(+)]", "gene_name": "Hpgd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHVNGKVALVTGAAQGIGKAFAEALLLHGAKVALVDWNLEAGVKCKAALDEQFEPQKTLFVQCDVADQKQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEQTLQINLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIIGFTRSAAMAANLMKSGVRLNVICPGFVDTPILESIEKEENMGQYIEYKDQIKAMMKFYGVLHPSTIANGLINLIEDDALNGAIMKITASKGIHFQDYDISPLLVKAPLTS", "length": 269 }, "evidence": [ { "id": "RGD:620087", "url": "https://alliancegenome.org/gene/RGD:620087#orthology", "database": "AGR" }, { "id": "HGNC:5154", "url": "https://alliancegenome.org/gene/HGNC:5154#orthology", "database": "AGR" }, { "id": "MGI:108085", "url": "https://alliancegenome.org/gene/MGI:108085#orthology", "database": "AGR" }, { "id": "FB:FBgn0036620", "url": 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Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VV75", "url": "https://www.uniprot.org/uniprotkb/Q9VV75" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VV75", "url": "https://www.uniprot.org/uniprotkb/Q9VV75" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VV75", "url": "https://www.uniprot.org/uniprotkb/Q9VV75" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VV75", "url": "https://www.uniprot.org/uniprotkb/Q9VV75" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VV75", "url": "https://www.uniprot.org/uniprotkb/Q9VV75" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VV75", "url": "https://www.uniprot.org/uniprotkb/Q9VV75" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VV75", "url": "https://www.uniprot.org/uniprotkb/Q9VV75" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VV75", "url": "https://www.uniprot.org/uniprotkb/Q9VV75" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VV75", "url": "https://www.uniprot.org/uniprotkb/Q9VV75" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VV75", "url": "https://www.uniprot.org/uniprotkb/Q9VV75" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VV75", "url": "https://www.uniprot.org/uniprotkb/Q9VV75" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG4169", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG4169", "resource": "KEGG Pathway" }, { "id": "R-DME-611105", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-611105", "resource": "Reactome", "description": "Respiratory electron transport" }, { "id": "R-DME-9837999", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9837999", "resource": "Reactome", "description": "Mitochondrial protein degradation" }, { "id": "R-DME-9865881", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9865881", "resource": "Reactome", "description": "Complex III assembly" } ], "orthologs": [ { "uniprot_canonical_ac": "F1QJE0-1", "protein_name": "Ubiquinol-cytochrome c reductase core protein 2a", "gene_name": "uqcrc2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMTGFRGFTHLSRRCYAAAARRNKALTEPLSHKSAAPPVLQPQDVQVSKLPSGLVVASLENYSPVSKIGVFVKAGSRYETAENLGVTHMLRLAANMTTKGASAFKICRSLEALGASLSVTSSREHMVYSLDFLRDDFDGVIEYLVDVTTAPDFRPWELADLTPRVKIDKALAEQSPQIGVLEKLHEAAYKNALSNSLYCPDIMLGKISVDHLQQFFDNNYTSARMALVGLGVSHAALKTVGERFFGSHKGAGAPGAKAVYRGGELRVQGTGSLVHALLACEGAVTGSAEANAFSVLQRILGAGPHVKRGSNISSKLSQGIAKATAQPFDATAFSTTYSDSGLFGLYIISQADSTREVISSAVAQVTAVAEGKLTTDDLTRAKNQLKADYLMSLESSDVLLEELGVQLLNSGVYSSPQTVTQSIDSVTSSDVLKAARRFVEGQKSMSSCGYLENTPFLDEL", "length": 460 }, "evidence": [ { "id": "MGI:1914253", "url": "https://alliancegenome.org/gene/MGI:1914253#orthology", "database": "AGR" }, { "id": "HGNC:12586", "url": "https://alliancegenome.org/gene/HGNC:12586#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RPD2-1", "protein_name": "Cytochrome b-c1 complex subunit 2, mitochondrial", "gene_name": "UQCRC2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKLITRAGSFSRFYSLKVAPKALASAAPAGVPLQPQDLEFTRLPNGLVIASLENYAPASRIGLFIKAGSRYEDSNNLGTSHLLRLASSLTTKGASSFKITRGIEAVGGKLSVTSTRESMAYTVECLRDDIEILMEFLLNVTAAPEFRRWEVAALQSQLRIDKAVAFQNPQAQVLENLHAAAYRNALANSLYCPDYRIGKVTPDQLHYYVQNHFTSARMALIGLGVSHPVLKQVAERFLNMRGGLGLSGAKAKYRGGEIRDQNGDSLVHAALVAESAATGSAEANAFSVLQHVLGAGPHVKRGSNATSSLYQAVAKGVHQPFDVSAFNASYSDSGLFGIYTISQAASAGDVIKSAYDQVKTIAQGNLSNTDVQAAKNKLKAGYLMSVESSEGFLDEVGSQALVAGSYVQPSTVLQQIDSVADADVINAAKKFVSGRKSMAASGNLGHTPFVDEL", "length": 453 }, "evidence": [ { "id": "Q9VV75", "url": "https://omabrowser.org/oma/group/Q9VV75/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3IGA2-1", "protein_name": "Cytochrome b-c1 complex subunit 2, mitochondrial", "gene_name": "LOC100750822", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKFLSKAGSFSRFYSLKVAPKVKTPVPPAGVPLQPEDLEFTKLPNGLVIASLENYAPLSRIGLFVKAGSRYEDSNNLGTSHLLRLASSLTTKGASSFKITRGIEAIGGKLSVAATRENMAYTIEGMRNDIEILMEFLLNVTTAPEFRRWEVAALQSQLKIDKAVAFQNSQTRVIENLHDAAYKNTLANPLYCPDYRVGKVTSEQLHYFIQNHFTSARMALVGLGVSHSVLKQVAEQFLNMRGGLGSAGAKATYRGGEIREQNGDNLVHAAIVAESAAIGDTGANAFSVLQHLLGAGPHIKRGNNTTSLLSQSVAKGSNQPFDVSAFNASYSDSGLFGIYTISQAEAAGDVIKAAYNQVKAVAQGNLSSADVQAAKNKLKAGYLMSVETSEGFLSEIGSQALLAGSYMSPPTFLQQIDSVADADVIKAAKKFVSGKKSMAASGNLGHTPFLDEL", "length": 453 }, "evidence": [ { "id": "Q9VV75", "url": "https://omabrowser.org/oma/group/Q9VV75/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P07257-1", "protein_name": "Cytochrome b-c1 complex subunit 2, mitochondrial", "gene_name": "QCR2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLSAARLQFAQGSVRRLTVSARDAPTKISTLAVKVHGGSRYATKDGVAHLLNRFNFQNTNTRSALKLVRESELLGGTFKSTLDREYITLKATFLKDDLPYYVNALADVLYKTAFKPHELTESVLPAARYDYAVAEQCPVKSAEDQLYAITFRKGLGNPLLYDGVERVSLQDIKDFADKVYTKENLEVSGENVVEADLKRFVDESLLSTLPAGKSLVSKSEPKFFLGEENRVRFIGDSVAAIGIPVNKASLAQYEVLANYLTSALSELSGLISSAKLDKFTDGGLFTLFVRDQDSAVVSSNIKKIVADLKKGKDLSPAINYTKLKNAVQNESVSSPIELNFDAVKDFKLGKFNYVAVGDVSNLPYLDEL", "length": 368 }, "evidence": [ { "id": "RGD:1359150", "url": "https://alliancegenome.org/gene/RGD:1359150#orthology", "database": "AGR" }, { "id": "MGI:1914253", "url": "https://alliancegenome.org/gene/MGI:1914253#orthology", "database": "AGR" }, { "id": "HGNC:12586", "url": "https://alliancegenome.org/gene/HGNC:12586#orthology", "database": "AGR" }, { "id": "FB:FBgn0250814", "url": "https://alliancegenome.org/gene/FB:FBgn0250814#orthology", "database": "AGR" }, { "id": "SGD:S000006395", "url": "https://alliancegenome.org/gene/SGD:S000006395#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P22695-1", "protein_name": "Cytochrome b-c1 complex subunit 2, mitochondrial", "gene_name": "UQCRC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKLLTRAGSFSRFYSLKVAPKVKATAAPAGAPPQPQDLEFTKLPNGLVIASLENYSPVSRIGLFIKAGSRYEDFSNLGTTHLLRLTSSLTTKGASSFKITRGIEAVGGKLSVTATRENMAYTVECLRGDVDILMEFLLNVTTAPEFRRWEVADLQPQLKIDKAVAFQNPQTHVIENLHAAAYRNALANPLYCPDYRIGKVTSEELHYFVQNHFTSARMALIGLGVSHPVLKQVAEQFLNMRGGLGLSGAKANYRGGEIREQNGDSLVHAAFVAESAVAGSAEANAFSVLQHVLGAGPHVKRGSNTTSHLHQAVAKATQQPFDVSAFNASYSDSGLFGIYTISQATAAGDVIKAAYNQVKTIAQGNLSNTDVQAAKNKLKAGYLMSVESSECFLEEVGSQALVAGSYMPPSTVLQQIDSVANADIINAAKKFVSGQKSMAASGNLGHTPFVDEL", "length": 453 }, "evidence": [ { "id": "RGD:1359150", "url": "https://alliancegenome.org/gene/RGD:1359150#orthology", "database": "AGR" }, { "id": "MGI:1914253", "url": "https://alliancegenome.org/gene/MGI:1914253#orthology", "database": "AGR" }, { "id": "HGNC:12586", "url": "https://alliancegenome.org/gene/HGNC:12586#orthology", "database": "AGR" }, { "id": "FB:FBgn0250814", "url": "https://alliancegenome.org/gene/FB:FBgn0250814#orthology", "database": "AGR" }, { "id": "SGD:S000006395", "url": "https://alliancegenome.org/gene/SGD:S000006395#orthology", "database": "AGR" }, { "id": "Q9VV75", "url": "https://omabrowser.org/oma/group/Q9VV75/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P23004-1", "protein_name": "Cytochrome b-c1 complex subunit 2, mitochondrial", "gene_name": "UQCRC2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKLLTRAGSLSRFYSLKVAPKVKATEAPAGVPPHPQDLEFTRLPNGLVIASLENYAPASRIGLFIKAGSRYENSNNLGTSHLLRLASSLTTKGASSFKITRGIEAVGGKLSVTSTRENMAYTVECLRDDVDILMEFLLNVTTAPEFRRWEVAALQPQLRIDKAVALQNPQAHVIENLHAAAYRNALANSLYCPDYRIGKVTPVELHDYVQNHFTSARMALIGLGVSHPVLKQVAEQFLNIRGGLGLSGAKAKYHGGEIREQNGDSLVHAALVAESAAIGSAEANAFSVLQHVLGAGPHVKRGSNATSSLYQAVAKGVHQPFDVSAFNASYSDSGLFGFYTISQAASAGDVIKAAYNQVKTIAQGNLSNPDVQAAKNKLKAGYLMSVESSEGFLDEVGSQALAAGSYTPPSTVLQQIDAVADADVINAAKKFVSGRKSMAASGNLGHTPFIDEL", "length": 453 }, "evidence": [ { "id": "Q9VV75", "url": "https://omabrowser.org/oma/group/Q9VV75/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P32551-1", "protein_name": "Cytochrome b-c1 complex subunit 2, mitochondrial", "gene_name": "Uqcrc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKLLSRAGSFSRFYSLKVAPKLKTSAPGGVPLQPQELEFTKLPNGLVIASLENYAPLSRIGLFIKAGSRYENYNYLGTSHLLRLASTLTTKGASSFKITRGIEAVGGKLSVTATRENMAYTVEGIRDDIEILMEFLLNVTTAPEFRRWEVAALRSQLKIDKAVAFQNPQTRIIENLHDVAYKNALANPLYCPDYRMGKITSEELHYFVQNHFTSARMALVGLGVSHSILKEVAEQFLNIRGGLGLAGAKAKYRGGEIREQNGDNLVHAAIVAESAAIGNAEANAFSVLQHLLGAGPHIKRGNNTTSLLSQSVAKGSQQPFDVSAFNASYSDSGLFGIYTVSQAAAAGDVINAAYNQVKAVAQGNLSSADVQAAKNKLKAGYLMSVETSEGFLSEIGSQALATGSYMPPPTVLQQIDAVADADVVKAAKKFVSGKKSMTASGNLGHTPFLDEL", "length": 452 }, "evidence": [ { "id": "RGD:1359150", "url": "https://alliancegenome.org/gene/RGD:1359150#orthology", "database": "AGR" }, { "id": "MGI:1914253", "url": "https://alliancegenome.org/gene/MGI:1914253#orthology", "database": "AGR" }, { "id": "HGNC:12586", "url": "https://alliancegenome.org/gene/HGNC:12586#orthology", "database": "AGR" }, { "id": "FB:FBgn0250814", "url": "https://alliancegenome.org/gene/FB:FBgn0250814#orthology", "database": "AGR" }, { "id": "SGD:S000006395", "url": "https://alliancegenome.org/gene/SGD:S000006395#orthology", "database": "AGR" }, { "id": "Q9VV75", "url": "https://omabrowser.org/oma/group/Q9VV75/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q54F93-1", "protein_name": "Mitochondrial-processing peptidase subunit alpha-2", "gene_name": "mppA2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIGRFIARNYTTSIFQESKRIVESTTLSNGLKVVSLVGGYTGPAVSLGLYIKTGSRNETQETAGLNQVLKGLAFESNTNKLGIEVQRDIEVSGSTAFAQASRDNLLIALQTLPNRSLQMLNNLANITKPTLPYHEVRDVTEIIVKESEAYNHDSYSSIFESVHQTAFRGKTLGRPLVAPICNLGNITKDAVTNWVNSTYKPSNMILVGVGLSHNELIEEAEKVTFGNDESSTSISNETAQYIGGESLKYSSGNSKVVLAFEGTAQSNIKDVAAFSVLQSILGNGCPKTAPGHGRTSRLFSLTKNNSNIVNSEAFNLTYGDSGLFGVVAEVEGATVGKTVSLITSEIVAASKTAGQELERAKAVTKSSVLEQAESRTSALEFIGKQAIYTDKVLTPAEFAEEISKVTSEDIKRVAKKMTSKKPTLVVVGDVSDAPTIESVQSQLKL", "length": 445 }, "evidence": [ { "id": "Q9VV75", "url": "https://omabrowser.org/oma/group/Q9VV75/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9DB77-1", "protein_name": "Cytochrome b-c1 complex subunit 2, mitochondrial", "gene_name": "Uqcrc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLLSRAGSFSRFYSLKVAPKVKTSAAPGGVPLQPQDLEFTKLPNGLVIASLENYAPLSRIGLFVKAGSRYEDSNNLGTSHLLRLASSLTTKGASSFKITRGIEAVGGKLSVTATRENMAYTVEGIRSDIEILMEFLLNVTTAPEFRRWEVAALRSQLKIDKAVAFQNSQTRIIENLHDVAYKNALANPLYCPDYRMGKITSEELHYFVQNHFTSARMALVGLGVSHSVLKQVAEQFLNMRGGLGLAGAKAKYRGGEIREQNGDNLVHAAIVAESAAIGNAEANAFSVLQHLLGAGPHIKRGNNTTSLLSQSVAKGSHQPFDVSAFNASYSDSGLFGIYTISQAAAAGEVINAAYNQVKAVAQGNLSSADVQAAKNKLKAGYLMSVETSEGFLSEIGSQALAAGSYMPPSTVLQQIDSVADADVVKAAKKFVSGKKSMAASGNLGHTPFLDEL", "length": 453 }, "evidence": [ { "id": "RGD:1359150", "url": "https://alliancegenome.org/gene/RGD:1359150#orthology", "database": "AGR" }, { "id": "MGI:1914253", "url": "https://alliancegenome.org/gene/MGI:1914253#orthology", "database": "AGR" }, { "id": "HGNC:12586", "url": "https://alliancegenome.org/gene/HGNC:12586#orthology", "database": "AGR" }, { "id": "FB:FBgn0250814", "url": "https://alliancegenome.org/gene/FB:FBgn0250814#orthology", "database": "AGR" }, { "id": "SGD:S000006395", "url": "https://alliancegenome.org/gene/SGD:S000006395#orthology", "database": "AGR" }, { "id": "Q9VV75", "url": "https://omabrowser.org/oma/group/Q9VV75/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9VV75", "url": "https://www.uniprot.org/uniprotkb/Q9VV75" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q9VV75", "url": 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ubiquitin transferase OS=Drosophila melanogaster OX=7227 GN=mus302 PE=4 SV=1 CANONICAL=Q9VV99-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VV99", "url": "https://www.uniprot.org/uniprotkb/Q9VV99" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VV99", "url": "https://www.uniprot.org/uniprotkb/Q9VV99" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VV99", "url": "https://www.uniprot.org/uniprotkb/Q9VV99" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VV99", "url": "https://www.uniprot.org/uniprotkb/Q9VV99" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VV99", "url": "https://www.uniprot.org/uniprotkb/Q9VV99" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VV99", "url": "https://www.uniprot.org/uniprotkb/Q9VV99" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VV99", "url": "https://www.uniprot.org/uniprotkb/Q9VV99" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VV99", "url": "https://www.uniprot.org/uniprotkb/Q9VV99" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VV99", "url": "https://www.uniprot.org/uniprotkb/Q9VV99" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VV99", "url": "https://www.uniprot.org/uniprotkb/Q9VV99" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VV99", "url": "https://www.uniprot.org/uniprotkb/Q9VV99" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG13025", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG13025", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A1A6-1", "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "Rfwd3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSDLVPAVVAHEAMDCGLQVPLDGTLEQAAPTEVISHGAPLLQPPPSDLVSSQGEALVQPAPADVVSSQGGLPTLQPVPPASIDLTEEVQPAEENMEIVDPGTSEERSEGSGTNGAVGAAPSVSMNYFISGLQRLHTMLELLRPSSSQSDHSAGGPIRRRRRTGFVSRARTGGSQRLNNARLRTFFQVSRSQPYPVASAHGSEARTPPSGTDSDSDSSAENEEAAARAEEPEAAVPEQGVISTDQEAASVTGGDASPKKQSPQKPIVLPTVEDEEGETCTICLEQWTSAGDHRLSALRCGHLFGYRCIFKWLKGQTRKCPQCNKKAKHSDIVVLYARSLRALDTTEQERMKSDLLSEQALRKQAELESAQCRLQLQVLMDKCTKLNSRVQDLEKLMVRHQGPAGQQCSGSQALCGSCLPSSQSQRKYSSEKTFTVSQTGNCRIMAYCDGLSCLVASQPSPQASFLPGFGVKMLSTANMRSSQYIPMHSKQIRGLAFSNQSKGLLLSASLDNTIKLTSLETNTVVQTYNTGRPVWSCCWCLDENNYIYAGLANGSILIYDLRNTNTYVQELVPQKARCPLVSLSYLPRAAVTAFPYGGVLAGTLENASFWELKTDFCHKPHVLSLEPGGFVDFQTESSTRHCLVTYRPDKSHNTVRTVLLEMSYRLDDAGEPVCSCLPVQTFLGGPTCKLLTKSAIFQSPENDGSVLVCTADEASQSALVWNAGSGSLLQNLKTDEPVLDICPFETNQNSYLATLTEKIVHIYKWE", "length": 765 }, "evidence": [ { "id": "RGD:1305243", "url": "https://alliancegenome.org/gene/RGD:1305243#orthology", "database": "AGR" }, { "id": "HGNC:25539", "url": "https://alliancegenome.org/gene/HGNC:25539#orthology", "database": "AGR" }, { "id": "MGI:2384584", "url": "https://alliancegenome.org/gene/MGI:2384584#orthology", "database": "AGR" }, { "id": "FB:FBgn0287696", "url": "https://alliancegenome.org/gene/FB:FBgn0287696#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6PCD5-1", "protein_name": "E3 ubiquitin-protein ligase RFWD3", "gene_name": "RFWD3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAHEAMEYDVQVQLNHAEQQPAPAGMASSQGGPALLQPVPADVVSSQGVPSILQPAPAEVISSQATPPLLQPAPQLSVDLTEVEVLGEDTVENINPRTSEQHRQGSDGNHTIPASSLHSMTNFISGLQRLHGMLEFLRPSSSNHSVGPMRTRRRVSASRRARAGGSQRTDSARLRAPLDAYFQVSRTQPDLPATTYDSETRNPVSEELQVSSSSDSDSDSSAEYGGVVDQAEESGAVILEEQLAGVSAEQEVTCIDGGKTLPKQPSPQKSEPLLPSASMDEEEGDTCTICLEQWTNAGDHRLSALRCGHLFGYRCISTWLKGQVRKCPQCNKKARHSDIVVLYARTLRALDTSEQERMKSSLLKEQMLRKQAELESAQCRLQLQVLTDKCTRLQRRVQDLQKLTSHQSQNLQQPRGSQAWVLSCSPSSQGQHKHKYHFQKTFTVSQAGNCRIMAYCDALSCLVISQPSPQASFLPGFGVKMLSTANMKSSQYIPMHGKQIRGLAFSSYLRGLLLSASLDNTIKLTSLETNTVVQTYNAGRPVWSCCWCLDEANYIYAGLANGSILVYDVRNTSSHVQELVAQKARCPLVSLSYMPRAASAAFPYGGVLAGTLEDASFWEQKMDFSHWPHVLPLEPGGCIDFQTENSSRHCLVTYRPDKNHTTIRSVLMEMSYRLDDTGNPICSCQPVHTFFGGPTCKLLTKNAIFQSPENDGNILVCTGDEAANSALLWDAASGSLLQDLQTDQPVLDICPFEVNRNSYLATLTEKMVHIYKWE", "length": 774 }, "evidence": [ { "id": "RGD:1305243", "url": "https://alliancegenome.org/gene/RGD:1305243#orthology", "database": "AGR" }, { "id": "HGNC:25539", "url": "https://alliancegenome.org/gene/HGNC:25539#orthology", "database": "AGR" }, { "id": "MGI:2384584", "url": "https://alliancegenome.org/gene/MGI:2384584#orthology", "database": "AGR" }, { "id": "FB:FBgn0287696", "url": "https://alliancegenome.org/gene/FB:FBgn0287696#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CIK8-1", "protein_name": "E3 ubiquitin-protein ligase RFWD3", "gene_name": "Rfwd3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEVAVGQASDLVPSEMDHEVIYSHLQGPLEGTIEPATPTEVVSNGAPLQPAPAELANSQGGAHVQPAPAEVVSSQDGLPTLQPLPPASIDLTEEVQPSEENMEVVNPGTSEEPSQGSGANPTAGAARSVSMNNFISGLQRLHNMLELLRPPPADHSVGPIRTRRRMAPILRARAGESQRQDNGRYVPHTPLYAYFQVSRSQPYPLPAAHDSETRNPPSGTDSDSDGSAEDEEVVVQAEEPEANIPEQGVIATDQEATSVTGDDAVPKESPQKPNMLSAMEDEEGETCTICLEQWTNAGDHRISALRCGHLFGFRCISKWLKGQTRKCPQCNKKAKHSDIVVIYARSLRALDTSEQERMKSDLLNEQMLRKQAELESAQCRLQLQVLIDKCTKLNSRVQDLEKFVVRHQNSAAQQCSRSKALCGKCLSSSQSPGKYSSEKTFTISQTGKCRILAYCDGLSCLVASQPSPQASFLPGFGVKMLSTANMKSSQYIPMHNKQIRGLSFSSQSKGLLLSASLDCTIKLTSLETNTVVQTYNTGRPVWSCCWCLDENNYVYAGLASGSILIYDLRNTNTYIQELVPQKARCPLVSLSYLPKAAVAAFPYGGVLAGTLENASFWELKSDFSHKPHVLSLEPGGFVDFQTESSTRHCLVTYRPDKSHNTVRTVLLEMSYKLDDAGEPVCSCLPVQTFLGGPTCKLLTKSAIFQSPENNGNVLVCTGDEASQSTLLWNAGSGLLLQNLKAGEPVLDICPFETNQNSYLATLTEKTVHMYKWE", "length": 774 }, "evidence": [ { "id": "RGD:1305243", "url": "https://alliancegenome.org/gene/RGD:1305243#orthology", "database": "AGR" }, { "id": "HGNC:25539", "url": "https://alliancegenome.org/gene/HGNC:25539#orthology", "database": "AGR" }, { "id": "MGI:2384584", "url": "https://alliancegenome.org/gene/MGI:2384584#orthology", "database": "AGR" }, { "id": "FB:FBgn0287696", "url": "https://alliancegenome.org/gene/FB:FBgn0287696#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "X1WE22-1", "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "rfwd3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDMEVVMVSESGSSTEEEENDVAASVPEDRSRLPLRRAPRRRQIISQRPHAERVRRIQTLLQNTHNPPDTHNPPDTRTDPEPASSDSADQSRVQSTAETSSPAGPSVPAAAEAPAVELKTEVEASSDSSGSAAASPAGAADEADTEGESCSICFEPWTTAGEHRLAALRCGHLFGYVCISRWLTGGGNKCPQCNKPAKKTQIIFLYARRLKALDNTEEVRLKSRLELEQGSRRMEQLEVAQCRQQLQLMVDENTRLRKEVEELRRWKAQASAGSSQAASLSSSQRQDSGHYVFSKAVLVSQTGGSRVLAHCEPLGCLLASQPSPQATLMPGFGVKKISTATLKASQYVHIHSKQIRGLAFSQQQDGLLLSAALDNTIKLTSLMTNTVVQAYNTGRPVWSCCWCHDNNNYIYAGLSNGSVLVYDTRDTSTHVQELRPLRSSCPVVSLSYIPHSSTSSSFPCGGVIAGTLEGGCFWERHNDNTHTPHILPLESGNCTHIQAEAESRHCLVTYRPGRLNPSLRCVLMELSRTPQVDLQSSVCSCSPVQTFSAGSSCKLLTKNCVFRSPAGGGAALVCAGDEATNSTMVWDAGTGALLQKMPADLPVLDICPFEANQSSFLASLTEKMIKVYKWE", "length": 632 }, "evidence": [ { "id": "HGNC:25539", "url": "https://alliancegenome.org/gene/HGNC:25539#orthology", "database": "AGR" }, { "id": "MGI:2384584", "url": "https://alliancegenome.org/gene/MGI:2384584#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VV99", "url": "https://www.uniprot.org/uniprotkb/Q9VV99" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VV99", "url": "https://www.uniprot.org/uniprotkb/Q9VV99" } ], "pmid": "" }, { "name": "PML body", "id": "GO:0016605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016605", "evidence": [ { "database": "UniProtKB", "id": "Q9VV99", "url": "https://www.uniprot.org/uniprotkb/Q9VV99" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9VV99", "url": "https://www.uniprot.org/uniprotkb/Q9VV99" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "Q9VV99", "url": "https://www.uniprot.org/uniprotkb/Q9VV99" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "Q9VV99", "url": "https://www.uniprot.org/uniprotkb/Q9VV99" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q9VV99", "url": "https://www.uniprot.org/uniprotkb/Q9VV99" } ], "pmid": "" }, { "name": "interstrand cross-link repair", "id": "GO:0036297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036297", "evidence": [ { "database": "UniProtKB", "id": "Q9VV99", "url": "https://www.uniprot.org/uniprotkb/Q9VV99" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 165, "end_pos": 167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" }, { "start_pos": 424, "end_pos": 426, "annotation": "n_glycosylation_sequon" }, { "start_pos": 604, "end_pos": 606, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VV99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VV99" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 131, "end_pos": 180, "start_aa": "Cys", "end_aa": "Lys", 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familial prostate cancer", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "familial prostate cancer caused by mutation in EHBP1", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, 12", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, type 12", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "HPC12", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, 13", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the MSMB gene." }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "MSMB familial prostate cancer", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "familial prostate cancer caused by mutation in MSMB", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, 13", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, type 13", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "HPC13", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "HPC11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "HPC14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "prostate cancer, hereditary, 15", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "HPC15", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "prostate cancer, hereditary, 15", "description": "" }, { "id": "MONDO:0700275", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0700275", "name": "prostate cancer, hereditary", "description": "An instance of prostate cancer that is caused by an inherited genomic modification in an individual. Familial prostate cancer (FPC) is a malignant tumor of the prostate with an early onset. FPC is either asymptomatic or causes mictionary symptoms, erectile dysfunction, bone pain, venous compression and infectious or inflammatory syndrome (for the metastatic forms). It is also characterized by familial antecedents." }, { "id": "MIM:601518", "resource": "MIM", "url": "https://www.omim.org/entry/601518", "name": "Prostate cancer, hereditary, 1", "description": "Prostate cancer, hereditary, 1" }, { "id": "MIM:610997", "resource": "MIM", "url": "https://www.omim.org/entry/610997", "name": "Prostate cancer, hereditary, 9", "description": "Prostate cancer, hereditary, 9" }, { "id": "MIM:611868", "resource": "MIM", "url": "https://www.omim.org/entry/611868", "name": "Prostate cancer, hereditary, 12", "description": "Prostate cancer, hereditary, 12" }, { "id": "MIM:611928", "resource": "MIM", "url": "https://www.omim.org/entry/611928", "name": "Prostate cancer, hereditary, 13", "description": "Prostate cancer, hereditary, 13" }, { "id": "MIM:611955", "resource": "MIM", "url": "https://www.omim.org/entry/611955", "name": "Prostate cancer, hereditary, 11", "description": "Prostate cancer, hereditary, 11" }, { "id": "MIM:176807", "resource": "MIM", "url": "https://www.omim.org/entry/176807", "name": "Prostate cancer", "description": "Prostate cancer" } ], "unlinked_id_list": [], "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ] }, { "disease_id": "DOID:1612", "recommended_name": { "id": "DOID:1612", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland." }, "synonyms": [ { "id": "DOID:1612", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1612", "name": "breast tumor", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1612", "name": "malignant neoplasm of breast", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1612", "name": "malignant tumor of the breast", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1612", "name": "mammary cancer", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1612", "name": "mammary tumor", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1612", "name": "primary breast cancer", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "hereditary breast carcinoma", "description": "Breast carcinoma that has developed in relatives of patients with history of breast carcinoma." }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer susceptibility, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, early-onset, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, invasive ductal, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, lobular, somatic", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, male, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, protection against, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, somatic", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial breast cancer", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial breast carcinoma", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial cancer of breast", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial cancer of the breast", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "hereditary breast cancer", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "hereditary breast carcinoma", "description": "" }, { "id": "MIM:114480", "resource": "MIM", "url": "https://www.omim.org/entry/114480", "name": "Breast cancer", "description": "Breast cancer" } ], "unlinked_id_list": [ "DOID:3017", "DOID:0050938" ], "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ] }, { "disease_id": "DOID:162", "recommended_name": { "id": "DOID:162", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis." }, "synonyms": [ { "id": "DOID:162", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:162", "name": "malignant neoplasm", "description": "" }, { "id": "DOID:162", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:162", "name": "malignant tumor", "description": "" }, { "id": "DOID:162", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:162", "name": "primary cancer", "description": "" } ], "unlinked_id_list": [ "DOID:193", "DOID:7757", "DOID:2151", "DOID:3316", "DOID:370", "DOID:706", "DOID:5604", "DOID:184", "DOID:2599", "DOID:4706", "DOID:2174", "DOID:4015", "DOID:4203", "DOID:170", "DOID:10154", "DOID:3017", "DOID:5166", "DOID:1795", "DOID:3149", "DOID:8527", "DOID:0050938", "DOID:3093", "DOID:0060122", "DOID:201", "DOID:3303", "DOID:3350", "DOID:176", "DOID:2595", "DOID:5093", "DOID:0070003", "DOID:0080355", "DOID:368", "DOID:0080524", "DOID:9460", "DOID:0080639", "DOID:0050619", "DOID:0080638", "DOID:4907", "DOID:1325", "DOID:688", "DOID:771", "DOID:0060073", "DOID:672", "DOID:5772", "DOID:4645", "DOID:0080879", "DOID:4765", "DOID:1357", "DOID:5032", "DOID:0060083", "DOID:0050743", "DOID:4045", "DOID:5672", "DOID:3675", "DOID:5662", "DOID:192", "DOID:4043", "DOID:0060116", "DOID:0080364", "DOID:0060100", "DOID:3095", "DOID:0080525", "DOID:3541", "DOID:4230", "DOID:1294", "DOID:0050615", "DOID:0050687", "DOID:3953", "DOID:5158", "DOID:1039", "DOID:3973", "DOID:8858", "DOID:0060119", "DOID:3111", "DOID:60004", "DOID:5467", "DOID:1036", "DOID:2706", "DOID:3856", "DOID:3112", "DOID:3479", "DOID:2815", "DOID:660", "DOID:120", "DOID:2021", "DOID:4114", "DOID:0081452", "DOID:4455", "DOID:3451", "DOID:175", "DOID:4931", "DOID:3277", "DOID:1659", "DOID:4960", "DOID:3001", "DOID:2621", "DOID:1542", "DOID:3419", "DOID:6536", "DOID:3850" ], "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ] }, { "disease_id": "DOID:2394", "recommended_name": { "id": "DOID:2394", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2394", "name": "ovarian cancer", "description": "A female reproductive organ cancer that is located_in the ovary." }, "synonyms": [ { "id": "DOID:2394", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2394", "name": "malignant Ovarian tumor", "description": "" }, { "id": "DOID:2394", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2394", "name": "malignant tumour of ovary", "description": "" }, { "id": "DOID:2394", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2394", "name": "ovarian neoplasm", "description": "" }, { "id": "DOID:2394", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2394", "name": "ovary neoplasm", "description": "" }, { "id": "DOID:2394", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2394", "name": "primary ovarian cancer", "description": "" }, { "id": "DOID:2394", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2394", "name": "tumor of the Ovary", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "ovarian cancer", "description": "A primary or metastatic malignant neoplasm involving the ovary. Most primary malignant ovarian neoplasms are either carcinomas (serous, mucinous, or endometrioid adenocarcinomas) or malignant germ cell tumors. Metastatic malignant neoplasms to the ovary include carcinomas, lymphomas, and melanomas." }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "ovarian neoplasm", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "ovary neoplasm", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "tumor of the ovary", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "tumour of the ovary", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "cancer of ovary", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "cancer of the ovary", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "malignant neoplasm of ovary", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "malignant neoplasm of the ovary", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "malignant ovarian neoplasm", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "malignant ovarian tumor", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "malignant ovarian tumour", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "malignant ovary neoplasm", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "malignant tumor of ovary", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "malignant tumor of the ovary", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "malignant tumour of ovary", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "malignant tumour of the ovary", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "ovarian cancer", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "ovarian cancer, somatic", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "ovarian malignant tumor", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "ovarian malignant tumour", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "ovary cancer", "description": "" }, { "id": "MONDO:0011931", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011931", "name": "ovarian cancer, susceptibility to, 1", "description": "" }, { "id": "MONDO:0011931", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011931", "name": "OVCAS1", "description": "" }, { "id": "MONDO:0011931", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011931", "name": "ovarian cancer, susceptibility to", "description": "" }, { "id": "MONDO:0011931", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011931", "name": "ovarian cancer, susceptibility to, 1", "description": "" }, { "id": "MIM:167000", "resource": "MIM", "url": "https://www.omim.org/entry/167000", "name": "Ovarian cancer", "description": "Ovarian cancer" } ], "unlinked_id_list": [ "DOID:2151" ], "evidence": [ { "id": "2394", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2394" } ] }, { "disease_id": "DOID:2870", "recommended_name": { "id": "DOID:2870", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2870", "name": "endometrial adenocarcinoma", "description": "An endometrial carcinoma that derives_from epithelial cells of glandular origin." }, "synonyms": [ { "id": "DOID:2870", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2870", "name": "endometrial endometrioid adenocarcinoma with squamous differentiation", "description": "" }, { "id": "DOID:2870", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2870", "name": "adenocarcinoma of endometrium", "description": "" }, { "id": "DOID:2870", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2870", "name": "adenocarcinoma of the Endometrium", "description": "" }, { "id": "DOID:2870", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2870", "name": "adenocarcinoma of uterus", "description": "" }, { "id": "DOID:2870", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2870", "name": "endometrial adenoacanthoma", "description": "" }, { "id": "DOID:2870", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2870", "name": "endometrial endometrioid adenocarcinoma", "description": "" }, { "id": "DOID:2870", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2870", "name": "endometrioid adenoma or carcinoma", "description": "" }, { "id": "DOID:2870", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2870", "name": "endometrioid adenomas and carcinomas", "description": "" }, { "id": "DOID:2870", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2870", "name": "endometrioid carcinoma of Endometrium", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "2870", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2870" } ] }, { "disease_id": "DOID:2893", "recommended_name": { "id": "DOID:2893", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2893", "name": "cervix carcinoma", "description": "A cervical cancer that is located_in the cervix uteri or located_in the cervical area and that has_material_basis_in abnormally proliferating cells derives_from epithelial cells." }, "synonyms": [ { "id": "DOID:2893", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2893", "name": "cancer of cervix", "description": "" }, { "id": "DOID:2893", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2893", "name": "carcinoma cervix uteri", "description": "" }, { "id": "DOID:2893", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2893", "name": "carcinoma of cervix", "description": "" }, { "id": "DOID:2893", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2893", "name": "carcinoma of the Cervix Uteri", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "2893", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2893" } ] }, { "disease_id": "DOID:305", "recommended_name": { "id": "DOID:305", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:305", "name": "carcinoma", "description": "A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells." }, "synonyms": [ { "id": "DOID:305", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:305", "name": "epithelial cancer", "description": "" }, { "id": "DOID:305", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:305", "name": "epithelioma", "description": "" }, { "id": "DOID:305", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:305", "name": "malignant Epithelioma", "description": "" } ], "unlinked_id_list": [ "DOID:0080524", "DOID:0080525", "DOID:1542", "DOID:3112", "DOID:3973", "DOID:4455", "DOID:4931", "DOID:5662", "DOID:2599", "DOID:1294", "DOID:2151", "DOID:4015", "DOID:3149", "DOID:4907", "DOID:3451" ], "evidence": [ { "id": "305", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:305" } ] }, { "disease_id": "DOID:3459", "recommended_name": { "id": "DOID:3459", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3459", "name": "breast carcinoma", "description": "A breast cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells." }, "synonyms": [ { "id": "DOID:3459", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3459", "name": "Mammary carcinoma", "description": "" }, { "id": "DOID:3459", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3459", "name": "carcinoma of breast", "description": "" } ], "unlinked_id_list": [ "DOID:0050938" ], "evidence": [ { "id": "3459", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3459" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VVA7", "url": "https://www.uniprot.org/uniprotkb/Q9VVA7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "TSG101", "url": "https://www.uniprot.org/uniprotkb/Q9VVA7", "locus": { "chromosome": "3L", "start_pos": 16844585, "end_pos": 16842294, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0036666", "url": "https://www.ensemblgenomes.org/id/FBgn0036666" } ] } } ], "crossref": [ { "id": "FB:FBgn0036666", "url": "https://alliancegenome.org/gene/FB:FBgn0036666", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0036666", "url": "https://bgee.org/?page=gene&gene_id=FBgn0036666", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11685", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11685", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0036666", "url": "https://flybase.org/reports/FBgn0036666", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "39881", "url": "https://www.ncbi.nlm.nih.gov/gene/39881", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VVA7", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VVA7*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR008883", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008883", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017916", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017916", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037202", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037202", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052070", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052070", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG9712", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG9712", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YMNFPQP", "url": "https://omabrowser.org/oma/group/YMNFPQP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VVA7", "url": "https://www.orthodb.org/?gene=Q9VVA7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23306", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23306", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23306:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23306:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05743", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05743", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09454", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09454", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-917729", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-917729", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_524120", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524120", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VVA7", "url": "https://www.uniprot.org/uniprotkb/Q9VVA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VVA7-1", "url": "https://www.uniprot.org/uniprotkb/Q9VVA7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPAVEETQITKYLSKYKYVAATKKDVVDVVTSFRSLTYDLQRFVFNDGSSKELFTIQGTIPVVYKNNTYYIPICIWLMDTHPQNAPMCFVKPTPTMQIKVSMYVDHNGKVYLPYLHDWQPHSSDLLSLIQVMIVTFGDHPPVYSKPKEQIAAPYPTNSYMPQPGAPGGSNSFLPYPTAGGAGGSNFPPYPTGSNVGPYPPTPAGPAGGSGYPAYPNFIQPTAGGYPPAAGYNPSNPSSTGTITEEHIKASIISAIDDKLRRRVQEKVNQYQAEIETLNRTKQELLEGSAKIDAIIERLEREHIDMQKNISILKDKEQELEKALEDLESAEAINPDEAVTTTAPLYRQLLNAYADEAATEDAIYYLGEGLRGGVIDLETFLKHVRQLSRKQFILRATMQKCRQKAGLAG", "length": 408, "header": "tr|Q9VVA7-1|Q9VVA7_DROME Isoform 1 of Tumor susceptibility gene 101 OS=Drosophila melanogaster OX=7227 GN=TSG101 PE=1 SV=2 CANONICAL=Q9VVA7-1" }, "isoforms": [ { "isoform_ac": "Q9VVA7-1", "url": "https://www.uniprot.org/uniprotkb/Q9VVA7/entry#Q9VVA7-1", "sequence": { "sequence": "MPAVEETQITKYLSKYKYVAATKKDVVDVVTSFRSLTYDLQRFVFNDGSSKELFTIQGTIPVVYKNNTYYIPICIWLMDTHPQNAPMCFVKPTPTMQIKVSMYVDHNGKVYLPYLHDWQPHSSDLLSLIQVMIVTFGDHPPVYSKPKEQIAAPYPTNSYMPQPGAPGGSNSFLPYPTAGGAGGSNFPPYPTGSNVGPYPPTPAGPAGGSGYPAYPNFIQPTAGGYPPAAGYNPSNPSSTGTITEEHIKASIISAIDDKLRRRVQEKVNQYQAEIETLNRTKQELLEGSAKIDAIIERLEREHIDMQKNISILKDKEQELEKALEDLESAEAINPDEAVTTTAPLYRQLLNAYADEAATEDAIYYLGEGLRGGVIDLETFLKHVRQLSRKQFILRATMQKCRQKAGLAG", "length": 408, "header": "tr|Q9VVA7-1|Q9VVA7_DROME Isoform 1 of Tumor susceptibility gene 101 OS=Drosophila melanogaster OX=7227 GN=TSG101 PE=1 SV=2 CANONICAL=Q9VVA7-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 177, "start_aa": "Thr", "end_pos": 177, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr177", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 201, "start_aa": "Thr", "end_pos": 201, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr201", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 93, "start_aa": "Thr", "end_pos": 93, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr93", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VVA7", "url": "https://www.uniprot.org/uniprotkb/Q9VVA7" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VVA7", "url": "https://www.uniprot.org/uniprotkb/Q9VVA7" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVA7", "url": "https://www.uniprot.org/uniprotkb/Q9VVA7" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVA7", "url": "https://www.uniprot.org/uniprotkb/Q9VVA7" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VVA7", "url": "https://www.uniprot.org/uniprotkb/Q9VVA7" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VVA7", "url": "https://www.uniprot.org/uniprotkb/Q9VVA7" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VVA7", "url": "https://www.uniprot.org/uniprotkb/Q9VVA7" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVA7", "url": "https://www.uniprot.org/uniprotkb/Q9VVA7" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVA7", "url": "https://www.uniprot.org/uniprotkb/Q9VVA7" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VVA7", "url": "https://www.uniprot.org/uniprotkb/Q9VVA7" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VVA7", "url": "https://www.uniprot.org/uniprotkb/Q9VVA7" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG9712", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG9712", "resource": "KEGG Pathway" }, { "id": "R-DME-917729", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-917729", "resource": "Reactome", "description": "Endosomal Sorting Complex Required For Transport (ESCRT)" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6ALM7-1", "protein_name": "UEV and lactate/malate dehyrogenase domains", "gene_name": "Uevld", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "VFLACRGRRRGGKMYKFRDLTVEELKTVNMSFPHFRYSMDTYVFKDTSQKDLLNFTGTIPVMYQGKTYNIPIRFWILDSHPFAPPICFLKPTANMEISVGKHVDAKGRIYLPYLQNWSHPKSVIVGLIKEMIAKFQEELPLYSVPSSNEAQQVDLLAYITKITEGVSDINSRGWTNHENKIPNKITVVGSGDLGIACTLAISAKGIADKLLLLDLSDGTNQGTMDLDIFNLPNVEISKDLSASAHSKVVIFTANSLGGSESYLHAVQSNVDMFRALVPALGHYSQHAVLLVASQPVEIMSYVTWKLSTFPAARVMGIGCNLDSQRLQYIISSVLKAQTSGKEVWVVGEQGENKVCSWSGQDGVMSPSSQAQLSSRAMGLLKVKGQRSWSVGLSVADLLDTIINNKKKVHSVSTLAKGYYGLDNEVFLSLPCILGTSGVSEVLKTAAEDAVTEALQTSASSIHGLQQQLKL", "length": 470 }, "evidence": [ { "id": "SGD:S000000514", "url": "https://alliancegenome.org/gene/SGD:S000000514#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7F4Y8-1", "protein_name": "Tumor susceptibility gene 101 protein", "gene_name": "tsg101b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSAINESSLRKVFSKYYKYRDLTARDITNVTNIYKDLKPMMDNYVFNDGSTKELLSLTGTVPVNYRGNIYNIPVCLWLLDTYPYNPPICFVKPTSAMMIKPGKHVDANGKVYLPYLHEWKPPQSDLYGLIQVMIVVFGEEPPVFSRPSSQPAYPAFPAAGPPNTSYMPTPQGLPYSQGHSANPGVFQGYPYPATGSGYPTTSGSSMYTPMSSVPTVGPSRDGTIGEDTIRASLVSAVSDKLRRRMKEEMDGAQAELDALRRTEEDLKRGHQKLEEMVTKLDVEMAEVDRNIDRLKQKDEELTAALERMENQAEDNDIDDVIVPTAPLYKQILNLYAEENAIEDTIFYLGEALRRDVIDLDVFLKHVRLLSRKQFQLRALMQKARKIAGLSDLY", "length": 393 }, "evidence": [ { "id": "MGI:106581", "url": "https://alliancegenome.org/gene/MGI:106581#orthology", "database": "AGR" }, { "id": "HGNC:15971", "url": "https://alliancegenome.org/gene/HGNC:15971#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P25604-1", "protein_name": "Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease", "gene_name": "STP22", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSANGKISVPEAVVNWLFKVIQPIYNDGRTTFHDSLALLDNFHSLRPRTRVFTHSDGTPQLLLSIYGTISTGEDGSSPHSIPVIMWVPSMYPVKPPFISINLENFDMNTISSSLPIQEYIDSNGWIALPILHCWDPAAMNLIMVVQELMSLLHEPPQDQAPSLPPKPNTQLQQEQNTPPLPPKPKSPHLKPPLPPPPPPQPASNALDLMDMDNTDISPTNHHEMLQNLQTVVNELYREDVDYVADKILTRQTVMQESIARFHEIIAIDKNHLRAVEQAIEQTMHSLNAQIDVLTANRAKVQQFSSTSHVDDEDVNSIAVAKTDGLNQLYNLVAQDYALTDTIECLSRMLHRGTIPLDTFVKQGRELARQQFLVRWHIQRITSPLS", "length": 385 }, "evidence": [ { "id": "MGI:106581", "url": "https://alliancegenome.org/gene/MGI:106581#orthology", "database": "AGR" }, { "id": "HGNC:15971", "url": "https://alliancegenome.org/gene/HGNC:15971#orthology", "database": "AGR" }, { "id": "FB:FBgn0036666", "url": "https://alliancegenome.org/gene/FB:FBgn0036666#orthology", "database": "AGR" }, { "id": "RGD:3909", "url": "https://alliancegenome.org/gene/RGD:3909#orthology", "database": "AGR" }, { "id": "SGD:S000000514", "url": "https://alliancegenome.org/gene/SGD:S000000514#orthology", "database": "AGR" }, { "id": "Q9VVA7", "url": "https://omabrowser.org/oma/group/Q9VVA7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q3U1V6-1", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 3", "gene_name": "Uevld", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEFDCEGVRRLLGKYKFRDLTVEELKNVSVSFPHFRYSVDTYVFKDTSQKDLLNFTGTIPVMYQGKTYNIPIRFWILDSHPFAPPICFLKPTANMEISVGKHVDAKGRIYLPYLQNWSHPKSAIVGLIKEMIAKFQEELPLYSIPSSNEAQQVDLLAYITKITEGVSDINSRGWTNHENKILNKITVVGSGDLGIACTLAISAKGIADKLLLLDLSDGMSQGTMDLDIFNLPNVEISKDLSASAHSKVVIFTANSLGGSESYLHAVQSNVDMFRALVPALGHYSQHAVLLVASQPVEIMSYVTWKLSTFPATRVVGIGCNLDSQRLQYIITSVLKVQTSGKEVWVVGEQGENKVCSWSGRDGVLSPSSQAQLSSRAMELLKVKGQRSWSVGLSVADLVDTIINNKRKVHSVSTLAKGYYGLDNEVFLSLPCILGTGGVSEVIKTKAGEDTVTGTLQASASSIHALQQQLEL", "length": 471 }, "evidence": [ { "id": "SGD:S000000514", "url": "https://alliancegenome.org/gene/SGD:S000000514#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q54LJ3-1", "protein_name": "ESCRT-I complex subunit tsg101", "gene_name": "tsg101", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYGHHGYPMHAHQQQMVNPTLAIVDNKMHTLSTFLNYIRAYRDPLRISKDLKETFHLFPNLSPFYENIPNRVNLICIKGTIPICFKGINYYLPIIVWVPLNYPQEFPTMVLDPTPEMRIVKNHHHVNLQGLVYHPYISSWSSNSTMETRVSQQQQPQPPQNNISPPPYGSSPTNNNVAAQQQQPPPPYGSSPSTSNSSSYTQPPPSYDSIKNKTNNTSSLPPPKQPQTSPPPPPTQQQQQQQNNNIIPPPQQPSPPPAYTEPTAAKQQQQQTSPSVKPLPPLPPQPVIDKKSEMVDQCTIKLQELLSKFYDTTSLEIKDFEAHNKSLEELSKKKLLEKEELSNQLATYNSQIDQLNENIEQLEKWINENDKSDSNIDIDQILGPKDSLSKQLLKLVSDDSTIEDLLYYLDKALHSNRISLEEYLKNVRSLSRDQFIIRATVKKVQFIIRQNQQQLQQQQQQQNSPQRQQYNQQQYFSK", "length": 478 }, "evidence": [ { "id": "Q9VVA7", "url": "https://omabrowser.org/oma/group/Q9VVA7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q61187-1", "protein_name": "Tumor susceptibility gene 101 protein", "gene_name": "Tsg101", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAVSESQLKKMMSKYKYRDLTVRQTVNVIAMYKDLKPVLDSYVFNDGSSRELVNLTGTIPVRYRGNIYNIPICLWLLDTYPYNPPICFVKPTSSMTIKTGKHVDANGKIYLPYLHDWKHPRSELLELIQIMIVIFGEEPPVFSRPTVSASYPPYTATGPPNTSYMPGMPSGISAYPSGYPPNPSGYPGCPYPPAGPYPATTSSQYPSQPPVTTVGPSRDGTISEDTIRASLISAVSDKLRWRMKEEMDGAQAELNALKRTEEDLKKGHQKLEEMVTRLDQEVAEVDKNIELLKKKDEELSSALEKMENQSENNDIDEVIIPTAPLYKQILNLYAEENAIEDTIFYLGEALRRGVIDLDVFLKHVRLLSRKQFQLRALMQKARKTAGLSDLY", "length": 391 }, "evidence": [ { "id": "MGI:106581", "url": "https://alliancegenome.org/gene/MGI:106581#orthology", "database": "AGR" }, { "id": "HGNC:15971", "url": "https://alliancegenome.org/gene/HGNC:15971#orthology", "database": "AGR" }, { "id": "FB:FBgn0036666", "url": "https://alliancegenome.org/gene/FB:FBgn0036666#orthology", "database": "AGR" }, { "id": "RGD:3909", "url": "https://alliancegenome.org/gene/RGD:3909#orthology", "database": "AGR" }, { "id": "SGD:S000000514", "url": "https://alliancegenome.org/gene/SGD:S000000514#orthology", "database": "AGR" }, { "id": "Q9VVA7", "url": "https://omabrowser.org/oma/group/Q9VVA7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6DBY5-1", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 3", "gene_name": "uevld", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDVNSEPVKKVLSKYKFRDVAVEELQKVYRVYPDMKIMAGTYTSSDSLQKDLLKLVGNIPVVYQGRSYNIPILLWLLDSFPFTPPICYLRPTSSMVIREGKHVDSKGRIHLPALHNWDHPKSSVNALLAEMIGKFEEEPPLGTKSSAHGDTPSNLLDYVSNLTITEGGNRPDQEVKVSVIGGGDLGIAAVLSIMAKSCVDKLVLIDIPENSTKGGTMDLEIFSLPKVEVSKDLSASAGSKVLVITANAWSDEQSYLSVVQTNVDMYRGIIPRLAQLSPNAVLVIASQPVDVMTHVAWRQSHLLPTQVIGVGCNLDSQRLSHIINISLVANNTGKQAWVIGELSENKVAVWGNMGPGTDQLQALTPVSNSTKPLMDRAFEMIKGRGQRSWSVGLSIADITHSIVTNQKKVHSVTTLAEGWGGIGSKVFLSLPCILGETGSTRLPGVALGSEDEMKLRESVACQVNLFMQLRL", "length": 471 }, "evidence": [ { "id": "SGD:S000000514", "url": "https://alliancegenome.org/gene/SGD:S000000514#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6IRE4-1", "protein_name": "Tumor susceptibility gene 101 protein", "gene_name": "Tsg101", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVSESQLKKMMSKYKYRDLTVRQTVNVIAMYKDLKPVLDSYVFNDGSSRELVNLTGTIPVRYRGNIYNIPICLWLLDTYPYNPPICFVKPTSSMTIKTGKHVDANGKIYLPYLHDWKHPRSELLELIQIMIVIFGEEPPVFSRPTVSASYPPYTAAGPPNTSYLPSMPSGISAYPSGYPPNPSGYPGCPYPPAGPYPATTSSQYPSQPPVTTAGPSRDGTISEDTIRASLISAVSDKLRWRMKEEMDGAQAELNALKRTEEDLKKGHQKLEEMVTRLDQEVAEVDKNIELLKKKDEELSSALEKMENQSENNDIDEVIIPTAPLYKQILNLYAEENAIEDTIFYLGEALRRGVIDLDVFLKHVRLLSRKQFQLRALMQKARKTAGLSDLY", "length": 391 }, "evidence": [ { "id": "MGI:106581", "url": "https://alliancegenome.org/gene/MGI:106581#orthology", "database": "AGR" }, { "id": "HGNC:15971", "url": "https://alliancegenome.org/gene/HGNC:15971#orthology", "database": "AGR" }, { "id": "FB:FBgn0036666", "url": "https://alliancegenome.org/gene/FB:FBgn0036666#orthology", "database": "AGR" }, { "id": "RGD:3909", "url": "https://alliancegenome.org/gene/RGD:3909#orthology", "database": "AGR" }, { "id": "SGD:S000000514", "url": "https://alliancegenome.org/gene/SGD:S000000514#orthology", "database": "AGR" }, { "id": "Q9VVA7", "url": "https://omabrowser.org/oma/group/Q9VVA7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8IX04-1", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 3", "gene_name": "UEVLD", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEFDCEGLRRLLGKYKFRDLTVEELRNVNVFFPHFKYSMDTYVFKDSSQKDLLNFTGTIPVMYQGNTYNIPIRFWILDSHPFAPPICFLKPTANMGILVGKHVDAQGRIYLPYLQNWSHPKSVIVGLIKEMIAKFQEELPMYSLSSSDEARQVDLLAYIAKITEGVSDTNSKSWANHENKTVNKITVVGGGELGIACTLAISAKGIADRLVLLDLSEGTKGATMDLEIFNLPNVEISKDLSASAHSKVVIFTVNSLGSSQSYLDVVQSNVDMFRALVPALGHYSQHSVLLVASQPVEIMTYVTWKLSTFPANRVIGIGCNLDSQRLQYIITNVLKAQTSGKEVWVIGEQGEDKVLTWSGQEEVVSHTSQVQLSNRAMELLRVKGQRSWSVGLSVADMVDSIVNNKKKVHSVSALAKGYYDINSEVFLSLPCILGTNGVSEVIKTTLKEDTVTEKLQSSASSIHSLQQQLKL", "length": 471 }, "evidence": [ { "id": "SGD:S000000514", "url": "https://alliancegenome.org/gene/SGD:S000000514#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99816-1", "protein_name": "Tumor susceptibility gene 101 protein", "gene_name": "TSG101", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVSESQLKKMVSKYKYRDLTVRETVNVITLYKDLKPVLDSYVFNDGSSRELMNLTGTIPVPYRGNTYNIPICLWLLDTYPYNPPICFVKPTSSMTIKTGKHVDANGKIYLPYLHEWKHPQSDLLGLIQVMIVVFGDEPPVFSRPISASYPPYQATGPPNTSYMPGMPGGISPYPSGYPPNPSGYPGCPYPPGGPYPATTSSQYPSQPPVTTVGPSRDGTISEDTIRASLISAVSDKLRWRMKEEMDRAQAELNALKRTEEDLKKGHQKLEEMVTRLDQEVAEVDKNIELLKKKDEELSSALEKMENQSENNDIDEVIIPTAPLYKQILNLYAEENAIEDTIFYLGEALRRGVIDLDVFLKHVRLLSRKQFQLRALMQKARKTAGLSDLY", "length": 390 }, "evidence": [ { "id": "MGI:106581", "url": "https://alliancegenome.org/gene/MGI:106581#orthology", "database": "AGR" }, { "id": "HGNC:15971", "url": "https://alliancegenome.org/gene/HGNC:15971#orthology", "database": "AGR" }, { "id": "FB:FBgn0036666", "url": "https://alliancegenome.org/gene/FB:FBgn0036666#orthology", "database": "AGR" }, { "id": "RGD:3909", "url": "https://alliancegenome.org/gene/RGD:3909#orthology", "database": "AGR" }, { "id": "SGD:S000000514", "url": "https://alliancegenome.org/gene/SGD:S000000514#orthology", "database": "AGR" }, { "id": "Q9VVA7", "url": "https://omabrowser.org/oma/group/Q9VVA7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 11, "go_terms": [ { "name": "multivesicular body assembly", "id": "GO:0036258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036258", "evidence": [ { "database": "UniProtKB", "id": "Q9VVA7", "url": "https://www.uniprot.org/uniprotkb/Q9VVA7" } ], "pmid": "" }, { "name": "protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway", "id": "GO:0043328", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043328", "evidence": [ { "database": "UniProtKB", "id": "Q9VVA7", "url": "https://www.uniprot.org/uniprotkb/Q9VVA7" } ], "pmid": "" }, { "name": "neuron remodeling", "id": "GO:0016322", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016322", "evidence": [ { "database": "UniProtKB", "id": "Q9VVA7", "url": "https://www.uniprot.org/uniprotkb/Q9VVA7" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "Q9VVA7", "url": "https://www.uniprot.org/uniprotkb/Q9VVA7" } ], "pmid": "" }, { "name": "endosome to lysosome transport", "id": "GO:0008333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008333", "evidence": [ { "database": "UniProtKB", "id": "Q9VVA7", "url": "https://www.uniprot.org/uniprotkb/Q9VVA7" } ], "pmid": "" }, { "name": "receptor-mediated endocytosis", "id": "GO:0006898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006898", "evidence": [ { "database": "UniProtKB", "id": "Q9VVA7", "url": "https://www.uniprot.org/uniprotkb/Q9VVA7" } ], "pmid": "" }, { "name": "symbiont entry into host cell", "id": "GO:0046718", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046718", "evidence": [ { "database": "UniProtKB", "id": "Q9VVA7", "url": "https://www.uniprot.org/uniprotkb/Q9VVA7" } ], "pmid": "" }, { "name": "maintenance of apical/basal cell polarity", "id": "GO:0035090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035090", "evidence": [ { "database": "UniProtKB", "id": "Q9VVA7", "url": "https://www.uniprot.org/uniprotkb/Q9VVA7" } ], "pmid": "" }, { "name": "terminal branching, open tracheal system", "id": "GO:0007430", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007430", "evidence": [ { "database": "UniProtKB", "id": "Q9VVA7", "url": "https://www.uniprot.org/uniprotkb/Q9VVA7" } ], "pmid": "" }, { "name": "liquid clearance, open tracheal system", "id": "GO:0035002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035002", "evidence": [ { "database": "UniProtKB", "id": "Q9VVA7", "url": "https://www.uniprot.org/uniprotkb/Q9VVA7" } ], "pmid": "" }, { "name": "negative regulation of imaginal disc growth", "id": "GO:0045571", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045571", "evidence": [ { "database": "UniProtKB", "id": "Q9VVA7", "url": "https://www.uniprot.org/uniprotkb/Q9VVA7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VVA7", "url": "https://www.uniprot.org/uniprotkb/Q9VVA7" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "Q9VVA7", "url": "https://www.uniprot.org/uniprotkb/Q9VVA7" } ], "pmid": "" }, { "name": "ESCRT I complex", "id": "GO:0000813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000813", "evidence": [ { "database": "UniProtKB", "id": "Q9VVA7", "url": "https://www.uniprot.org/uniprotkb/Q9VVA7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin binding", "id": "GO:0043130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043130", "evidence": [ { "database": "UniProtKB", "id": "Q9VVA7", "url": "https://www.uniprot.org/uniprotkb/Q9VVA7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 278, "end_pos": 280, "annotation": "n_glycosylation_sequon" }, { "start_pos": 308, "end_pos": 310, "annotation": "n_glycosylation_sequon" }, { "start_pos": 66, "end_pos": 68, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VVA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVA7" }, { "id": "PS51312", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51312" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SB", "eco_id": "ECO_0000259", "start_pos": 342, "end_pos": 408, "start_aa": "Ala", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q9VVA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVA7" }, { "id": "PS51322", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51322" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UEV", "eco_id": "ECO_0000259", "start_pos": 3, "end_pos": 146, "start_aa": "Ala", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 93, 177, 201 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 278, "end_pos": 280 }, { "start_pos": 308, "end_pos": 310 }, { "start_pos": 66, "end_pos": 68 } ] }, "class_list": [], "section_stats": [ { "table_id": 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genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VVC0", "url": "https://www.uniprot.org/uniprotkb/Q9VVC0" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VVC0", "url": "https://www.uniprot.org/uniprotkb/Q9VVC0" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVC0", "url": "https://www.uniprot.org/uniprotkb/Q9VVC0" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVC0", "url": "https://www.uniprot.org/uniprotkb/Q9VVC0" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VVC0", "url": "https://www.uniprot.org/uniprotkb/Q9VVC0" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VVC0", "url": "https://www.uniprot.org/uniprotkb/Q9VVC0" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VVC0", "url": "https://www.uniprot.org/uniprotkb/Q9VVC0" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVC0", "url": "https://www.uniprot.org/uniprotkb/Q9VVC0" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVC0", "url": "https://www.uniprot.org/uniprotkb/Q9VVC0" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VVC0", "url": "https://www.uniprot.org/uniprotkb/Q9VVC0" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VVC0", "url": "https://www.uniprot.org/uniprotkb/Q9VVC0" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], 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224996.0 }, "refseq": { "ac": "NP_001097630", "name": "ephexin, isoform E", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097630" }, "gene_names": [ { "name": "Exn", "type": "recommended", "evidence": [ { "id": "Q9VVC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVC6" } ] }, { "name": "BcDNA:GH03693", "type": "synonym", "evidence": [ { "id": "NP_001097630", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097630" }, { "id": "Q9VVC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVC6" } ] }, { "name": "CG14060", "type": "synonym", "evidence": [ { "id": "NP_001097630", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097630" }, { "id": "Q9VVC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVC6" } ] }, { "name": "CG3799", "type": "synonym", "evidence": [ { "id": "NP_001097630", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097630" }, { "id": "Q9VVC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVC6" } ] }, { "name": "CG42665", "type": "synonym", "evidence": [ { "id": "NP_001097630", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097630" }, { "id": "Q9VVC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVC6" } ] }, { "name": "Dmel\\CG42665", "type": "synonym", "evidence": [ { "id": "NP_001097630", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097630" }, { "id": "Q9VVC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVC6" } ] }, { "name": "Dmel_CG42665", "type": "synonym", "evidence": [ { "id": "Q9VVC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVC6" } ] }, { "name": "Exn", "type": "synonym", "evidence": [ { "id": "NP_001097630", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097630" } ] }, { "name": "exn", "type": "synonym", "evidence": [ { "id": "NP_001097630", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097630" }, { "id": "Q9VVC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVC6" } ] } ], "protein_names": [ { "name": "CG42665-PE", "type": "synonym", "evidence": [ { "id": "NP_001097630", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097630" } ] }, { "name": "Ephexin, isoform D", "type": "synonym", "evidence": [ { "id": "Q9VVC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVC6/entry#names_and_taxonomy" } ] }, { "name": "Ephexin, isoform E", "type": "synonym", "evidence": [ { "id": "Q9VVC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVC6/entry#names_and_taxonomy" } ] }, { "name": "Exn-PE", "type": "synonym", "evidence": [ { "id": "NP_001097630", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097630" } ] }, { "name": "ephexin, isoform E", "type": "synonym", "evidence": [ { "id": "NP_001097630", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097630" } ] }, { "name": "ephexin", "type": "synonym", "evidence": [ { "id": "NP_001097630", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097630" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VVC6", "url": "https://www.uniprot.org/uniprotkb/Q9VVC6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Exn", "url": "https://www.uniprot.org/uniprotkb/Q9VVC6", "locus": { "chromosome": "3L", "start_pos": 16994388, "end_pos": 16970013, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0261547", "url": "https://www.ensemblgenomes.org/id/FBgn0261547" } ] } } ], "crossref": [ { "id": "FB:FBgn0261547", "url": "https://alliancegenome.org/gene/FB:FBgn0261547", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0261547", "url": "https://bgee.org/?page=gene&gene_id=FBgn0261547", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00160", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00160", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01221", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01221", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11793", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11793", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0261547", "url": "https://flybase.org/reports/FBgn0261547", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "39900", "url": "https://www.ncbi.nlm.nih.gov/gene/39900", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VVC6", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VVC6*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR000219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047270", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047270", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG42665", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG42665", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RACHDER", "url": "https://omabrowser.org/oma/group/RACHDER/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VVC6", "url": "https://www.orthodb.org/?gene=Q9VVC6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q9Y150", "url": "https://www.orthodb.org/?gene=Q9Y150", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12845", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12845", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12845:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12845:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00621", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00621", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-193648", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-193648", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-3928663", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-3928663", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-416482", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-416482", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-8980692", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8980692", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-9013148", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9013148", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001097630", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097630", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VVC6", "url": "https://www.uniprot.org/uniprotkb/Q9VVC6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VVC6-1", "url": "https://www.uniprot.org/uniprotkb/Q9VVC6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9Y150", "url": "https://www.uniprot.org/uniprotkb/Q9Y150", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9Y150-1", "url": "https://www.uniprot.org/uniprotkb/Q9Y150-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAMSPVLDAAAKAAGRDLNGNSNAASATAASTATPTAAAAAAATTPRKTKKTIINWLVNSDSENNNRATCDKAGKDNPNPNQNPNSQANPNQNCSCESRAFRDFRGVQTLRLLWSRRIKSASEDQCHSPVHCHTSSSSLGTLKKLNKSVSCLVNAFNNSRDCATPEKTLAKRAASLHNLQDSQAKHKQLHREKDNFYKYKNAEQAKMQAKLRSSADEAILNASETRAKRDDSGCLPGVKSYNSKALSAADKVAKVAKGEAKTQRRAEEPVGEAEVEVEVEFRAKREHNRLEGLSLSAASAQSGGSSESLQTTTTSSSTPTTHSSVTSSTGRSGGRRKYSFKTHAGKSYHQHHHPSRRTSNMDSSNGGISMVAKLTHQFNEIIQKDAKLLEQVKRNNGVWISRGTHVYKIVEKPTSEGKGLPNADDNRISTVQRNIKKFERLEKPSVPLKSEQLMRKHLELMRGSSLSRGPRIKRNLKLPPGSVGIPELAIVSEELKTPTSEEQAKKPKSVQNESQPNHPEELNQSNDKPSDELDLIMGEEGDEEELRQKQRKHKYASIYEKLRFTFAKGRKSASPSPTKAQIREEVSIDEESIKDSTSEDMVTRKEDFTLDLPKEVIPRAEDLEDSSHALLVSPCFEADAKILDALEAVDLKLKVLNPLNDVTTADGERELLLAANDDFEQRILPNSSFVYQAANKQYSNNQILLNQAVNVTLVNAIEGEQMIMEQKQLMKVRDLELTERDIDQPLKRAEKSPEKDDTLEPESLYEPITPVMDETKTEAQTSSLFKIYTKKSELVEDIYQTVEEASTVEVKPNNWLEGYESIAGSQEACPLTYDGYESFAPEEVVTTPTTPSATGTLGRNTRDELPELPKPKRVLNKSPIPLRPAPPKPQAKESEEDENIYDTIKGCYESMHCKATSSSSSGEATLTTDTISLSSNCYESISHIRRSRVATTQNQGHGSAGSCIQLSSSGSTLTISSDHKTNSLYESSLAAAGCVVYGSASVGCRSSLGSSAGSRDSGKPGDKRSSIAGSSDNSDAWVDISDGEIGQATTDATANEAQFIVVRERFKPHRTRSPDWSKRIRDKRLQQKKAISCIEDDSDHYYETLSPLGNKRHSTQLVRQSQDGNRSGGVRSSHRRSKNHSASAHTLGEHVVISDDYDSFETDSDDHGDGEPDLRQRNYNDSGVDMRNHRLPKPPPPQNQVYEFVRKFKDFISSKKSPKGSQQKLYENTPASTLFYVECSKRTEDVYENTDFGPERIPAPETKGPVHQEQAPVLRAKQKNGKSLRSRLRKSLVGSSFDTKQLSSLAPTRSTFYVEDPEGSLPALPLEPEIHGSGELDSGFSDKNCTPLPETPKFSTVARKAKKEAKANRRRTTIGLRPNDPPPPPPPMTGNKSPLDPERELDAEQTTSWYAECGVFKQATNGAVSPRGDEPVTPTPSGHGGVSSWYAESGLYQTSGISVASSSGSSGVSTGNEAGLGDELSSEPHSLFSNEPLYQMYSAAKLESITRDLEAHGSSDGYEEIGLQAKAKPEPLVKPRPTALQLVEPKNGPSRTLWSEIPEVIHSCILPTLTSRERSLQEAKFEIITSEASYLKSLNLLRRHFMNHNAFLDSSVLSAKDRKALFSYIVPVHECSERLLTELEACWQDNIMLLGLSRCIYEIAERHFHVYVAFCEHQGRMDRTLRRLKESKESLAFQQHLERLEASPSCCGLNLHSFLMLPMQRITRLPLLIDAVFSKESPLNREEYESWKLTLALVQKVVGQCNEAANRWEQAFELERIARQLEFPSHVRALAIAPVGVPRAGAKPRFLVKRGELTHLLWRGEDAKLTFGKRLTKISIYAFLFSDLLLLCKRRGESCFSVFDYCPRSMLTLAAGDSLPQLPTKDLKDQAGKNLILMTLLENCDRKTVELVLSCPSVSDQQRWLQAMRPPEAETPGEKLYESWDCPQVVAKHSYESDEPDVLQLELGDVVNVSRKLPDGWYQGERIRDGAVGWFPGSYTEELNSAHVRARNLKQRHRLLTFTATYLESQKSK", "length": 2029, "header": "tr|Q9VVC6-1|Q9VVC6_DROME Isoform 1 of Ephexin, isoform D OS=Drosophila melanogaster OX=7227 GN=Exn PE=4 SV=3 CANONICAL=Q9VVC6-1" }, "isoforms": [ { "isoform_ac": "Q9VVC6-1", "url": "https://www.uniprot.org/uniprotkb/Q9VVC6/entry#Q9VVC6-1", "sequence": { "sequence": "MAMSPVLDAAAKAAGRDLNGNSNAASATAASTATPTAAAAAAATTPRKTKKTIINWLVNSDSENNNRATCDKAGKDNPNPNQNPNSQANPNQNCSCESRAFRDFRGVQTLRLLWSRRIKSASEDQCHSPVHCHTSSSSLGTLKKLNKSVSCLVNAFNNSRDCATPEKTLAKRAASLHNLQDSQAKHKQLHREKDNFYKYKNAEQAKMQAKLRSSADEAILNASETRAKRDDSGCLPGVKSYNSKALSAADKVAKVAKGEAKTQRRAEEPVGEAEVEVEVEFRAKREHNRLEGLSLSAASAQSGGSSESLQTTTTSSSTPTTHSSVTSSTGRSGGRRKYSFKTHAGKSYHQHHHPSRRTSNMDSSNGGISMVAKLTHQFNEIIQKDAKLLEQVKRNNGVWISRGTHVYKIVEKPTSEGKGLPNADDNRISTVQRNIKKFERLEKPSVPLKSEQLMRKHLELMRGSSLSRGPRIKRNLKLPPGSVGIPELAIVSEELKTPTSEEQAKKPKSVQNESQPNHPEELNQSNDKPSDELDLIMGEEGDEEELRQKQRKHKYASIYEKLRFTFAKGRKSASPSPTKAQIREEVSIDEESIKDSTSEDMVTRKEDFTLDLPKEVIPRAEDLEDSSHALLVSPCFEADAKILDALEAVDLKLKVLNPLNDVTTADGERELLLAANDDFEQRILPNSSFVYQAANKQYSNNQILLNQAVNVTLVNAIEGEQMIMEQKQLMKVRDLELTERDIDQPLKRAEKSPEKDDTLEPESLYEPITPVMDETKTEAQTSSLFKIYTKKSELVEDIYQTVEEASTVEVKPNNWLEGYESIAGSQEACPLTYDGYESFAPEEVVTTPTTPSATGTLGRNTRDELPELPKPKRVLNKSPIPLRPAPPKPQAKESEEDENIYDTIKGCYESMHCKATSSSSSGEATLTTDTISLSSNCYESISHIRRSRVATTQNQGHGSAGSCIQLSSSGSTLTISSDHKTNSLYESSLAAAGCVVYGSASVGCRSSLGSSAGSRDSGKPGDKRSSIAGSSDNSDAWVDISDGEIGQATTDATANEAQFIVVRERFKPHRTRSPDWSKRIRDKRLQQKKAISCIEDDSDHYYETLSPLGNKRHSTQLVRQSQDGNRSGGVRSSHRRSKNHSASAHTLGEHVVISDDYDSFETDSDDHGDGEPDLRQRNYNDSGVDMRNHRLPKPPPPQNQVYEFVRKFKDFISSKKSPKGSQQKLYENTPASTLFYVECSKRTEDVYENTDFGPERIPAPETKGPVHQEQAPVLRAKQKNGKSLRSRLRKSLVGSSFDTKQLSSLAPTRSTFYVEDPEGSLPALPLEPEIHGSGELDSGFSDKNCTPLPETPKFSTVARKAKKEAKANRRRTTIGLRPNDPPPPPPPMTGNKSPLDPERELDAEQTTSWYAECGVFKQATNGAVSPRGDEPVTPTPSGHGGVSSWYAESGLYQTSGISVASSSGSSGVSTGNEAGLGDELSSEPHSLFSNEPLYQMYSAAKLESITRDLEAHGSSDGYEEIGLQAKAKPEPLVKPRPTALQLVEPKNGPSRTLWSEIPEVIHSCILPTLTSRERSLQEAKFEIITSEASYLKSLNLLRRHFMNHNAFLDSSVLSAKDRKALFSYIVPVHECSERLLTELEACWQDNIMLLGLSRCIYEIAERHFHVYVAFCEHQGRMDRTLRRLKESKESLAFQQHLERLEASPSCCGLNLHSFLMLPMQRITRLPLLIDAVFSKESPLNREEYESWKLTLALVQKVVGQCNEAANRWEQAFELERIARQLEFPSHVRALAIAPVGVPRAGAKPRFLVKRGELTHLLWRGEDAKLTFGKRLTKISIYAFLFSDLLLLCKRRGESCFSVFDYCPRSMLTLAAGDSLPQLPTKDLKDQAGKNLILMTLLENCDRKTVELVLSCPSVSDQQRWLQAMRPPEAETPGEKLYESWDCPQVVAKHSYESDEPDVLQLELGDVVNVSRKLPDGWYQGERIRDGAVGWFPGSYTEELNSAHVRARNLKQRHRLLTFTATYLESQKSK", "length": 2029, "header": "tr|Q9VVC6-1|Q9VVC6_DROME Isoform 1 of Ephexin, isoform D OS=Drosophila melanogaster OX=7227 GN=Exn PE=4 SV=3 CANONICAL=Q9VVC6-1" }, "locus": {} }, { "isoform_ac": "Q9Y150-1", "url": "https://www.uniprot.org/uniprotkb/Q9VVC6/entry#Q9Y150-1", "sequence": { "sequence": "MSALNRSNGQRLSCSGSLSSSGHPADPVTLPRKRRPRARGEVGVTCQGSSTVYLNGPVSAEPIRPAPEPIYQNEAAAISQRCSYSHQRAQLLTSMRVTVAEGAENDAKVTMEVSTFVDDSDHYYETLSPLGNKRHSTQLVRQSQDGNRSGGVRSSHRRSKNHSASAHTLGEHVVISDDYDSFETDSDDHGDGEPDLRQRNYNDSGVDMRNHRLPKPPPPQNQVYEFVRKFKDFISSKKSPKGSQQKLYENTPASTLFYVECSKRTEDVYENTDFGPERIPAPETKGPVHQEQAPVLRAKQKNGKSLRSRLRKSLVGSSFDTKQLSSLAPTRSTFYVEDPEGSLPALPLEPEIHGSGELDSGFSDKNCTPLPETPKFSTVARKAKKEAKANRRRTTIGLRPNDPPPPPPPMTGNKSPLDPERELDAEQTTSWYAECGVFKQATNGAVSPRGDEPVTPTPSGHGGVSSWYAESGLYQTSGISVASSSGSSGVSTGNEAGLGDELSSEPHSLFSNEPLYQMYSAAKLESITRDLEAHGSSDGYEEIGLQAKAKPEPLVKPRPTALQLVEPKNGPSRTLWSEIPEVIHSCILPTLTSRERSLQEAKFEIITSEASYLKSLNLLRRHFMNHNAFLDSSVLSAKDRKALFSYIVPVHECSERLLTELEACWQDNIMLLGLSRCIYEIAERHFHVYVAFCEHQGRMDRTLRRLKESKESLAFQQHLERLEASPSCCGLNLHSFLMLPMQRITRLPLLIDAVFSKESPLNREEYESWKLTLALVQKVVGQCNEAANRWEQAFELERIARQLEFPSHVRALAIAPVGVPRAGAKPRFLVKRGELTHLLWRGEDAKLTFGKRLTKISIYAFLFSDLLLLCKRRGESCFSVFDYCPRSMLTLAAGDSLPQLPTKDLKDQAGKNLILMTLLENCDRKTVELVLSCPSVSDQQRWLQAMRPPEAETPGEKLYESWDCPQVVAKHSYESDEPDVLQLELGDVVNVSRKLPDGWYQGERIRDGAVGWFPGSYTEELNSAHVRARNLKQRHRLLTFTATYLESQKSK", "length": 1051, "header": "tr|Q9Y150-1|Q9Y150_DROME Computationally mapped isoform of Ephexin, isoform B OS=Drosophila melanogaster OX=7227 GN=Exn PE=4 SV=1 CANONICAL=Q9VVC6-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1435, "start_aa": "Thr", "end_pos": 1435, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1435", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 769, "start_aa": "Thr", "end_pos": 769, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr769", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VVC6", "url": "https://www.uniprot.org/uniprotkb/Q9VVC6" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VVC6", "url": "https://www.uniprot.org/uniprotkb/Q9VVC6" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVC6", "url": "https://www.uniprot.org/uniprotkb/Q9VVC6" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVC6", "url": "https://www.uniprot.org/uniprotkb/Q9VVC6" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VVC6", "url": "https://www.uniprot.org/uniprotkb/Q9VVC6" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VVC6", "url": "https://www.uniprot.org/uniprotkb/Q9VVC6" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VVC6", "url": "https://www.uniprot.org/uniprotkb/Q9VVC6" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVC6", "url": "https://www.uniprot.org/uniprotkb/Q9VVC6" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVC6", "url": "https://www.uniprot.org/uniprotkb/Q9VVC6" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VVC6", "url": "https://www.uniprot.org/uniprotkb/Q9VVC6" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VVC6", "url": "https://www.uniprot.org/uniprotkb/Q9VVC6" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG42665", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG42665", "resource": "KEGG Pathway" }, { "id": "R-DME-193648", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-193648", "resource": "Reactome", "description": "NRAGE signals death through JNK" }, { "id": "R-DME-3928663", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-3928663", "resource": "Reactome", "description": "EPHA-mediated growth cone collapse" }, { "id": "R-DME-416482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-416482", "resource": "Reactome", "description": "G alpha (12/13) signalling events" }, { "id": "R-DME-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-DME-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9013148", "resource": "Reactome", "description": "CDC42 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"MSAQSLPAATPPTLKPPRIIRPRPPSRHRAPHSPGPPHNGSSPKALPQISNDASASVCTSIFWEPPTGSLKPPALLPPSVSRASLDSQTSPDSPSSTPSPSPVSRRSISPEPAPCSPVPPPKPSGSSRTPLPLGPVPLQDGSASAPGTVRRLAGKFEWGAEGKAQSADSLERCSQGSTDVNGEKETLQVGLSGNGSQENGTPDAALACPPCCPCVCHVAKPGLELRWVPVGSSDDILRAPCRASPLRASRSRINPPVISHPPVVLTSYRSTAERKLLPPLKPPKPTRVRQDTSTSGELPQPDLELPSEDGIQAAPKAWEGDRPEEAPQNAPPPVALEGREEEGLEGLKELQWELPLQDEPLYQTYRAAVLSEELWGVGEDGGPSPANPGEAPTFSRLPGPRNTLWQELPAVRGSGLLESLSPQERRMQESLFEVVTSEASYLRSLRLLTDTFVLSQALRDTLTPRDHHTLFSNVQRVQSVSERFLGTLLSRVRSSPHISDLCDVVHAHAVGPFSVYVDYVRNQQYQEETYSRLMDTNVRFSAELRRLQSLPKCERLPLPSFLLLPFQRITRLRMLLQNILSQTEEGSSRQENAQKALGAVSKIIERCSAEVGRMKQTEELIRLTQRLRFHKVKALPLVSWSRRLELQGELTELGCRRGGVLFTSRPRFTPLCLLLFSDLLLITQPKSGQRLQVLDYAHRSLVQAQQVPDPSGPPTFRLSLLSNHQGRPTHRLLQAASLSDMQRWLGAFPTPGPLPCSPDTIYEDCECSQELCSEPSTPSKTEGQSLESKAPRKHLHKNPEGWLKGLPGAFPAQLVCEVTGEHERRKHLRQHQKLLEAAGPSSDTPDTPQP", "length": 850 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-060526-292", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-292#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M6Z762-1", "protein_name": "Rho guanine nucleotide exchange factor 15", "gene_name": "arhgef15a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": 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"url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-292#orthology", "database": "AGR" }, { "id": "FB:FBgn0261547", "url": "https://alliancegenome.org/gene/FB:FBgn0261547#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3YYY8-1", "protein_name": "Rho guanine nucleotide exchange factor 26", "gene_name": "Arhgef26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDGESEVDFSSNGVTPLWRRRSTPPLQLLSRSKPRPQSYQSPSGLLITDFPVEELAALPTPQTPVRVPADPDDRTVSRSPQLLSAHRRPVTNGRTVSPDYRAASPRLRRPKSPLVSYAASGGSPKSTSNGTVASPAALLSRASRTPDTPASCATDEDCTGVTASKVSSPIANGLAHKTDSSGPVSQTGQPAGDLELAPSRLSPALPHKSSEQKLPLQRLPSQGNELPNPSVVLSTNSPAALKMGKQQIIPKSLASEIKLSKSNSQNVESHRRLLKVRSMVEGLGAPLGHEGEEGEVDNDMDSPGSLRRGLRSTSYRRAVVSGFDFDSPTSSKKKNRMSQPVLKAVMEDKEKFSSLGRIKKKILKGQGTFDGEENAVLYQNYKEKALDIDSDEEPEAKEQKAEERIVIHHKPLRSTWSQLSAVKRNGLSQTVSQEERKRQEAIFEVISSEHSYLLSLEILIRMFKNSKELTDTMTKTERHHLFSNITDVWEASKKFFTELEARHQNNIFIEDISDIVEKHTASTFDPYVKYCTNEVYQQRTLQKLLATNPSFKEVLSRIESHEDCRNLPMISFLILPMQRVTRLPLLMDTICQKTPKDSPKYEVCKRALKEVSKLVRLCNEGARKMERTEMMYTINSQLEFKIKPFPLVSSSRWLVKRGELTAYVEDTVLFSKRMSKQQVYFFLFNDVLIITKKKSEESYNVNDYSLRDQLLVESCDNEELNSSPGKNPSTMLYSRQSSATHLFTLTVLSNHASEKVDMLLGAETQSERARWITALGHSSGKQPPDRTTLTQVEIIRSFTAKQPDELSLQVADVVLIYQRVGDGWYEGERLRDGERGWFPMECAKEITCQATIDKNVERMGRLLGLETNV", "length": 869 }, "evidence": [ { "id": "HGNC:24490", "url": "https://alliancegenome.org/gene/HGNC:24490#orthology", "database": "AGR" }, { "id": "RGD:1562559", "url": "https://alliancegenome.org/gene/RGD:1562559#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D4A1D2-1", "protein_name": "Rho guanine nucleotide exchange factor 26", "gene_name": "Arhgef26", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDGESEVDFSSNGVTPLWRRRSTPPLQLLGRSKPRPQSYQSPSGLLITDFPVEELAALPAPQTPVPVPAGPEGRTVSRSPQLLCAHRRPVTNGRTVSPDYRAASPRLRRPKSPLVSYAASGGSPKSAVNGTVSSPAALLSRASRTPDIPASSAPGEDRTRVTASKVSSPTANGLAPKTDSSGPVSQTGQSAGDLEPSPSRLSPAPQHRSSEQKLPLQRLPSQGNELPNPSVILSTNSPAALKMGKQQIIPKSLASEIKLSKSNSQNVEPHRRLLKVRSMVEGLGAPLGPEGEESEADNDIDSPGSLRRGLRSTSYRRAVVSGFDFDSPTSSKKKNRMSQPVLKAVMEDKEKFSSLGRIKKKMLKGQGTFDGEENAVLYQNYKEKALDIDSDEEPEPKEQKPEEKIVIHHKPLRSTWSQLSAVKRNGLSQTVSQEERKRQEAIFEVISSEHSYLLSLEILIRMFKDSKELTDTMTKTERHHLFSNITDVWEASKKFFTELEARHQNNIFIEDISDIVEKHTASTFDPYVKYCTNEVYQQRTLQKLLTTNPSFKEVLSRIESHEDCRNLPMISFLILPMQRVTRLPLLMDTICQKTPKDSPKYEVCKRALKEVSKLVRLCNEGARKMERTEMMYTINSQLEFKIKPFPLVSSSRWLVKRGELTAYVEDTVLFSKRMSKQQVYFFLFNDVLIITKKKSEESYNVNDYSLRDQLLVESCDNEELNSSPGKNTSTMLYSRQSSATHLFTLTVLSNHANEKVDMLLGAETQSERARWITALGHSSGKQPPDRTTLTQVEITRSFTAKQPDELSLQVADVVLIYQRVGDGWYEGERLRDGERGWFPMECAKEITCQATIDKNVERMGRLLGLETNV", "length": 869 }, "evidence": [ { "id": "HGNC:24490", "url": "https://alliancegenome.org/gene/HGNC:24490#orthology", "database": "AGR" }, { "id": "RGD:1562559", "url": "https://alliancegenome.org/gene/RGD:1562559#orthology", "database": "AGR" }, { "id": "FB:FBgn0261547", "url": "https://alliancegenome.org/gene/FB:FBgn0261547#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A646-1", "protein_name": "Rho guanine nucleotide exchange factor 19", "gene_name": "Arhgef19", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCPLWYLPSSRRGPGGPPRRAALESVPKLLSLRPPFLWVSLLFLPDWALPLWPQGPLQGSSLPRLSTAQPGKCPGGWQRKGGMDCGPPATLQPHLAGPPGTARRPVAVCQQESLSFVELPTLHPPSPVCVDLFPITPEELQAPGSRWSLATPAPLQGLLWPTSSGGPDTHISTTGGMRPSRAGSWPHCPGAQPPTLVGPWSSQHMQPQRRASHGGSEKSAWRKMQVYHNEEATGGTEPPMGLLETGQAVQGQALCAQEPRPQELSGNTRGGLEAQERRRFSASELMTRLHSSLRLGRSTAPRALTSGSGAGVIREGKLPGREPRRAETRMDSVSLPAPVDLNEVQGGLVEPRLDTNDKPTQDTNSATERRQSRFLLNSVLYQEYSDVASARELRRQQREEEGPGDGAEGAEEGPGPPRANLSPSSSFRAQRSTRGSTFSLWQDIPDVRGSGVLATLSLRDCKLQEAKFELITSEASYIHSLSVAVGHFLGSVELSECLGTQDKQWLFSKLPEVKSTSERFLHDLEQRLEADVLRFSVCDVVLHHCPAFRRVYLPYVTNQAYQERTYQRLLLENPKFPGILARLEESPVCQRLPLTSFLILPFQRVTRLKMLVENILKRTTPGSQDEDMATKAFSALKELVQECNASVQSMKRTEELIHLSKKIHFEGKIFPLISQARWLVRHGELVELAPLPAAPPAKLKLSSKAVYLHLFNDCLLLSRRKELGKFAVFVHANMAELQVRDLSLKLQGIPGHVFLLRLLHGQRARHQLLLRARTESEKQRWISALRPSSPQEDKEITCDGEDRPQVQCVRTYKALQPDELTLEKTDILAVKTRTSDGWLEGVRLADGEKGWVPQAHVEEISSLSARLRNLREYKRVSNVSSKLGDPPA", "length": 888 }, "evidence": [ { "id": "HGNC:26604", "url": "https://alliancegenome.org/gene/HGNC:26604#orthology", "database": "AGR" }, { "id": "MGI:1925912", "url": "https://alliancegenome.org/gene/MGI:1925912#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7EY47-1", "protein_name": "Rho guanine nucleotide exchange factor 19", "gene_name": "arhgef19", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLPGYGISPLLDFQPHLQAFHCRGESSDMWFPGSVETQALSDSREGRPLLRQHQHIAVCQQETLAFIDLQEQSVNGFQSCTSENCSSSLCSKPLRCNGRSPSDFAKTESTDRALDDYLTEDINNVEVVQEQSWTYITGLPETVHENPDSGVKGLNPRNLFLPLSPIYAPGDRNSLESQQLSSPSSPLEGPDPFRPQRRTSLGSIKEKSIRRKMRVYSPDTLEASPSSPGVECDYLLPASFESFVEGGLGMVGSTIPTSQTSSPLPGLDEDLSLFAIPNSPKPFLNPLQEGARCQEGVNDEGRQRLGLEDCGTLQGPPLNSGTSMPLSRSRSVDNERRRFSASELISRLQLSQRKNSFTLKLGKSLSARVASRERHLSGNLSSDYKPNSRHRFSGGSSDSGPHSPVGSAPPLPSADSNQPLHRRSSKQRMRKVSVDEDGGSPPSNSKRLSRFLPSLILYQEYSDVAINREIQRQQGAEPGTDEERGESVSPGNLSPSSSFRSSRGSAFSLWQDIPDVRSSGQLDNFSNEERKLQEAKFELVTSEASYIRSLSIAVDHFMMSSELCECLGTQERQWLFSKLPDVKEVSERFLQDLERRLEGDILRFDVCDIVLDHCPALRRVYLPYVTNQAYQEQTYQRLLQENARFPGILARLEEDPICQRLPLTSFLILPFQRITRLKMLVENILKRTTPGSRDEDTATKALNELKKIIKECNSSVQSMKRMEELIHLNKKIHFEGKIFPLISQSRWLVKHGELLEVDTQNLSISGSKFKLTTRPVYLHLFNDCLLLSRRKESWKFMVFVHAKIEDLKVKDLSQKLQGISGFIFYLQLCEGQQLKHQILLKSPTESSKQRWITAMFPSDPTTAIEQTNENDDLSQVQCIRSYQAQEHDELTLEKADILQAVTITSDGWVEGIRLSDGERGWFPKTYVEEITSRSARLRNLRENIRIKCVSQKLEGETL", "length": 958 }, "evidence": [ { "id": "HGNC:26604", "url": "https://alliancegenome.org/gene/HGNC:26604#orthology", "database": "AGR" }, { "id": "MGI:1925912", "url": "https://alliancegenome.org/gene/MGI:1925912#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FDB4-1", "protein_name": "Ephexin-1 isoform X1", "gene_name": "ngef", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMAMTALFRGKWGHNNKPQEVQTKPRTPVPQLPSEDDENEDETLRAPIRRNSRFYRSMRKKKSAGPSEQQESPSSSPKPTVDPASYNRLSPAAANRVPLSPRLQKSPPSRSGISLLSNGVQGGVRSRSPLASPGDWPRRLEMEELSERTTSACTMQDNDNHSTADPDNITFRLVRNGDSPQKMAVENSCHNLNIMKNVDVLYQEYRDTSKQQEIDQRRQRDGLPTAGSGVLAAPALQLQLRSSTNSLNLWQNLDAVKKSGLLQTLEPKEIILQEAMFELVTSEASYYKSLELLETHFLRNPLLVNTLSQSDMHFLFSNITDIMKASEKFLMDLEHRIEESILISDVCDIVHFHAVNHFQVFISYVINQVYQETNYRRILQENCAFRENMAILENQPKVKGLSFTSFLILPFQRITRLKLLVQNILKRVEENSEKERTAILAHQELEKIVKQCNEGARKMSRTEELISIEKTLEFKSKSVPVISHSRWLLKKGEVQQMSGPKSTRTMRSRKLYHPIYLFLFNNLLLITKRNSSGDKFQVLDSCSRSMLRTEDLEDQGQMLACVFVLKLLENQEDREVSYMLKTESVSDKLRWICALTPNRRTRFLSTSTHEPDSPQVQCIQSYSSQEPDELSVEMADVLHILECTDDGWILGERLHDGERGWFPNRVVERIMSAEVRAQNLKECQRIQQAQEGAQGTRAASRGRVAVRNSQYNASWTDL", "length": 718 }, "evidence": [ { "id": "HGNC:7807", "url": "https://alliancegenome.org/gene/HGNC:7807#orthology", "database": "AGR" }, { "id": "MGI:1858414", "url": "https://alliancegenome.org/gene/MGI:1858414#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O94989-1", "protein_name": "Rho guanine nucleotide exchange factor 15", "gene_name": "ARHGEF15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSAQSLPAATPPTQKPPRIIRPRPPSRSRAAQSPGPPHNGSSPQELPRNSNDAPTPMCTPIFWEPPAASLKPPALLPPSASRASLDSQTSPDSPSSTPTPSPVSRRSASPEPAPRSPVPPPKPSGSPCTPLLPMAGVLAQNGSASAPGTVRRLAGRFEGGAEGRAQDADAPEPGLQARADVNGEREAPLTGSGSQENGAPDAGLACPPCCPCVCHTTRPGLELRWVPVGGYEEVPRVPRRASPLRTSRSRPHPPSIGHPAVVLTSYRSTAERKLLPLLKPPKPTRVRQDATIFGDPPQPDLDLLSEDGIQTGDSPDEAPQNTPPATVEGREEEGLEVLKEQNWELPLQDEPLYQTYRAAVLSEELWGVGEDGSPSPANAGDAPTFPRPPGPRNTLWQELPAVQASGLLDTLSPQERRMQESLFEVVTSEASYLRSLRLLTDTFVLSQALRDTLTPRDHHTLFSNVQRVQGVSERFLATLLSRVRSSPHISDLCDVVHAHAVGPFSVYVDYVRNQQYQEETYSRLMDTNVRFSAELRRLQSLPKCERLPLPSFLLLPFQRITRLRMLLQNILRQTEEGSSRQENAQKALGAVSKIIERCSAEVGRMKQTEELIRLTQRLRFHKVKALPLVSWSRRLEFQGELTELGCRRGGVLFASRPRFTPLCLLLFSDLLLITQPKSGQRLQVLDYAHRSLVQAQQVPDPSGPPTFRLSLLSNHQGRPTHRLLQASSLSDMQRWLGAFPTPGPLPCSPDTIYEDCDCSQELCSESSAPAKTEGRSLESRAAPKHLHKTPEGWLKGLPGAFPAQLVCEVTGEHERRRHLRQNQRLLEAVGSSSGTPNAPPP", "length": 841 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-060526-292", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-292#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5BKC9-1", "protein_name": "Ephexin-1", "gene_name": "Ngef", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METKNSEDQGKPQRKSVSSLWKSKHGPAEMRPELPPETAKETQNEEPRCLIPIQRNSLFNRAMRHKHKARSMSERRANDQAGDLPETRKSVNEPLAFNLPQGRLPPWRTPAQRGPGAQEASESSSTPGNGTTPEECPALTDSPTTLTEALQMIHPIPADSWRNLIEQIGLLYQEYRDKSTLQEIETRRQQDAEIQGNSDGSQAGEDNAEEEEEEEEEPASPPERRALPQICLLSNPHSRFNLWQDLPEIQSSGVLDILQPEETKLQEAMFELVTSEASYYKSLNLLVSHFMENERLKKILHPSEAHILFSNVLDVMAVSERFLLELEHRMEENIVISDVCDIVYRYAADHFSVYITYVSNQTYQERTYKQLLQEKTAFRELIAQLELDPKCKGLPLSSFLILPFQRITRLKLLVQNILKRVEEGSEREGTALDAHKELEMVVKACNEGVRKMSRTEQMISIQKKMEFKIKSVPIISHSRWLLKQGELQQMSGPKTSRTLRTKKLFREIYLFLFNDLLVICRQIPGDKYQVFDSAPRGLLRVEELEDQGQTLANVFILRLLENADDREATYMLKASSQSEMKRWMTSLAPNRRTKFVSFTSRLLDCPQVQCVHPYVAQQPDELTLELADILNILEKTEDGWIFGERLHDQERGWFPSSMTEEILNPKIRSQNLKECFRVHKMEDPQRSQNKDRRKLGSRNRQ", "length": 701 }, "evidence": [ { "id": "HGNC:7807", "url": "https://alliancegenome.org/gene/HGNC:7807#orthology", "database": "AGR" }, { "id": "MGI:1858414", "url": "https://alliancegenome.org/gene/MGI:1858414#orthology", "database": "AGR" }, { "id": "RGD:1309055", "url": "https://alliancegenome.org/gene/RGD:1309055#orthology", "database": "AGR" }, { "id": "FB:FBgn0261547", "url": "https://alliancegenome.org/gene/FB:FBgn0261547#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5FWH6-1", "protein_name": "Rho guanine nucleotide exchange factor 15", "gene_name": "Arhgef15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAQSLPAATPPTLKPPRIIRPRPPSRHRAPHSPGPLHNGSSPKALPQISNDASASVCTSIFWEPPTASLKPPALLPPSVSRTSLDSQTSPDSPSSTPSPSPVSRRSISPEPAPCSPVPPPKPSGSSRTPLPSGPTPLQDGSASAPGTVRRLAGKFEWGAEGKAQSSDSLERCSQGSTEVNGEKETPEAALSGNGSQENGTPDAALACPPCCPCVCHVAKPGLELRWVPVGSSEDILRIPCRASPLRASRSRINPPVISHPPVVLTSYRSTAERKLLPPLKPPKPTKVRQDISTSEELPQPDLKLPSEDGIQTATKAWEGDRPEGAPLNAPPVALEGREEEGLDGLKGLQWELPLQDEPLYQTYRAAVLSEELWGVGEDGGPSPANPGEAPTFSRLPGPRNTLWQELPAVRGSGLLESLSPQERRMQESLFEVVTSEASYLRSLRLLTDTFVLSQALRDTLTPRDHHTLFSNVQRVQSVSERFLGTLLSRVRSSPHITDLCDVVHAHAVGPFFVYVDYVRNQQYQEETYSRLMDTNVRFSAELRRLQSLPKCERLPLPSFLLLPFQRITRLRMLLQNILSQTEEGSSRQENAQKALGAVSKIIERCSAEVGRMKQTEELIRLTQRLRFHKVKALPLVSWSRRLELQGELTELGCRRGGVLFTSRPRFTPLCLLLFSDLLLITQPKSGQRLQVLDYAHRSLVQAQQVPDPSGPPTFRLSLLSNHQGRPTHRLLQAASLSDMQRWLGAFPTPGPLPCSPDTIYEDCECSQELCSEPSTPSKTEGQSLESKAPRKHLHKNPEGWLKGLPGAFPAQLVCEVTGEHERRKHLRQHQKLLEAVGPSSGTPDTPQP", "length": 849 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-060526-292", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-292#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8BWA8-1", "protein_name": "Rho guanine nucleotide exchange factor 19", "gene_name": "Arhgef19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDCGPPATLQPHLAGPPGTARRPVAVCQQESLSFVELPPSRLCVDLFPIAPEELQAPGSRWSLATPAPLQGLLWPTSPGGPDTHIASTSGGMRPGRAGSWPHCPGAQPPTLVEPWSSQHMQPQRRASHSGSEKSAWRKMQVYHNEEATGTETPTGLLETGQAAQEQALCALEPGPQELSGNARGGLEAPERRRFSASELMTRLHSSLRLGRSTATRVLTSGSGAGAIREGKLPVRESRRAETRADSVSLPGPVDLNEVHGGLVEPRLDTQDKPTQDPSSATERRQSRFLLNSVLYQEYSDVASARELRRQQREEEGPGDGAEGAEEGPGPPRANLSPSSSFRAQRSTRGSTFSLWQDIPDVRGSGVLATLSLRDCKLQEAKFELITSEASYIHSLSVAVGHFLGSVELSECLGTQDKQWLFSKLPEVKSTSERFLHDLEQRLEADVLRFSVCDVVLHHCPAFRRVYLPYVTNQAYQERTYQRLLLENPKFPGILARLEESPVCQRLPLTSFLILPFQRVTRLKMLVENILKRTAPGSQDEDMATKAFSALKELVQECNASVQSMKRTEELIHLSKKIHFEGKIFPLISQARWLVRHGELVELAPLPAAPPAKLKLSSKAVYLHLFNDCLLLSRRKELGKFAVFVHANMAELQVRDLSLKLQGIPGHVFLLRLLHGQRARHQLLLRARTESEKQRWISALRPSSPQEDKEITCDGEDRPQVQCVRTYKALQPDELTLEKTDILAVKTRTSDGWLEGVRLADGEKGWVPQAHVVEISSLSARLRNLREYKRVSNASSKLGDPPA", "length": 802 }, "evidence": [ { "id": "HGNC:26604", "url": "https://alliancegenome.org/gene/HGNC:26604#orthology", "database": "AGR" }, { "id": "MGI:1925912", "url": "https://alliancegenome.org/gene/MGI:1925912#orthology", "database": "AGR" }, { "id": "FB:FBgn0261547", "url": "https://alliancegenome.org/gene/FB:FBgn0261547#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CHT1-1", "protein_name": "Ephexin-1", "gene_name": "Ngef", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METKNSEDWGKPQRKSESSSRKSNHGPAEMRPALPPENREAPETGEETQNEEPRRLIPIQRHSLFNRAVRHRHKARSTSERRASDQADLPKMGKSVNERSAFNLPQGRLSPWRTPAQRDTGAQEASESSSTPGNGTTPEECPALTDSPTTLTEALQMIHPIPADSWRNLIEQIGLLYQEYRDKSTLQEIETRRQQDAEIQGNSDGSQVGEDAGEEEEEEEEGEEEELASPPERRALPQICLLSNPHSRFNLWQDLPEIQSSGVLDILQPEEIRLQEAMFELVTSEASYYKSLNLLVSHFMENERLKKILHPSEAHILFSNVLDVMAVSERFLLELEHRMEENIVISDVCDIVYRYAADHFSVYITYVSNQTYQERTYKQLLQEKAAFRELIAQLELDPKCKGLPFSSFLILPFQRITRLKLLVQNILKRVEERSEREGTALDAHKELEMVVKACNEGVRKMSRTEQMISIQKKMEFKIKSVPIISHSRWLLKQGELQQMSGPKTSRTLRTKKLFREIYLFLFNDLLVICRQIPGDKYQVFDSAPRGLLRVEELEDQGQTLANVFILRLLENADDREATYMLKASSQSEMKRWMTSLAPNRRTKFVSFTSRLLDCPQVQCVHPYVAQQPDELTLELADILNILEKTEDGWIFGERLHDQERGWFPSSMTEEILNPKIRSQNLKECFRVHKMEDPQRSQNKDRRKLGSRNRQ", "length": 710 }, "evidence": [ { "id": "HGNC:7807", "url": "https://alliancegenome.org/gene/HGNC:7807#orthology", "database": "AGR" }, { "id": "MGI:1858414", "url": "https://alliancegenome.org/gene/MGI:1858414#orthology", "database": "AGR" }, { "id": "RGD:1309055", "url": "https://alliancegenome.org/gene/RGD:1309055#orthology", "database": "AGR" }, { "id": "FB:FBgn0261547", "url": "https://alliancegenome.org/gene/FB:FBgn0261547#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IW93-1", "protein_name": "Rho guanine nucleotide exchange factor 19", "gene_name": "ARHGEF19", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDCGPPATLQPHLTGPPGTAHHPVAVCQQESLSFAELPALKPPSPVCLDLFPVAPEELRAPGSRWSLGTPAPLQGLLWPLSPGGSDTEITSGGMRPSRAGSWPHCPGAQPPALEGPWSPRHTQPQRRASHGSEKKSAWRKMRVYQREEVPGCPEAHAVFLEPGQVVQEQALSTEEPRVELSGSTRVSLEGPERRRFSASELMTRLHSSLRLGRNSAARALISGSGTGAAREGKASGMEARSVEMSGDRVSRPAPGDSREGDWSEPRLDTQEEPPLGSRSTNERRQSRFLLNSVLYQEYSDVASARELRRQQREEEGPGDEAEGAEEGPGPPRANLSPSSSFRAQRSARGSTFSLWQDIPDVRGSGVLATLSLRDCKLQEAKFELITSEASYIHSLSVAVGHFLGSAELSECLGAQDKQWLFSKLPEVKSTSERFLQDLEQRLEADVLRFSVCDVVLDHCPAFRRVYLPYVTNQAYQERTYQRLLLENPRFPGILARLEESPVCQRLPLTSFLILPFQRITRLKMLVENILKRTAQGSEDEDMATKAFNALKELVQECNASVQSMKRTEELIHLSKKIHFEGKIFPLISQARWLVRHGELVELAPLPAAPPAKLKLSSKAVYLHLFNDCLLLSRRKELGKFAVFVHAKMAELQVRDLSLKLQGIPGHVFLLQLLHGQHMKHQFLLRARTESEKQRWISALCPSSPQEDKEVISEGEDCPQVQCVRTYKALHPDELTLEKTDILSVRTWTSDGWLEGVRLADGEKGWVPQAYVEEISSLSARLRNLRENKRVTSATSKLGEAPV", "length": 802 }, "evidence": [ { "id": "HGNC:26604", "url": "https://alliancegenome.org/gene/HGNC:26604#orthology", "database": "AGR" }, { "id": "MGI:1925912", "url": "https://alliancegenome.org/gene/MGI:1925912#orthology", "database": "AGR" }, { "id": "FB:FBgn0261547", "url": "https://alliancegenome.org/gene/FB:FBgn0261547#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8N5V2-1", "protein_name": "Ephexin-1", "gene_name": "NGEF", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METRESEDLEKTRRKSASDQWNTDNEPAKVKPELLPEKEETSQADQDIQDKEPHCHIPIKRNSIFNRSIRRKSKAKARDNPERNASCLADSQDNGKSVNEPLTLNIPWSRMPPCRTAMQTDPGAQEMSESSSTPGNGATPEEWPALADSPTTLTEALRMIHPIPADSWRNLIEQIGLLYQEYRDKSTLQEIETRRQQDAEIEDNTNGSPASEDTPEEEEEEEEEEEPASPPERKTLPQICLLSNPHSRFNLWQDLPEIRSSGVLEILQPEEIKLQEAMFELVTSEASYYKSLNLLVSHFMENERIRKILHPSEAHILFSNVLDVLAVSERFLLELEHRMEENIVISDVCDIVYRYAADHFSVYITYVSNQTYQERTYKQLLQEKAAFRELIAQLELDPKCRGLPFSSFLILPFQRITRLKLLVQNILKRVEERSERECTALDAHKELEMVVKACNEGVRKMSRTEQMISIQKKMEFKIKSVPIISHSRWLLKQGELQQMSGPKTSRTLRTKKLFHEIYLFLFNDLLVICRQIPGDKYQVFDSAPRGLLRVEELEDQGQTLANVFILRLLENADDREATYMLKASSQSEMKRWMTSLAPNRRTKFVSFTSRLLDCPQVQCVHPYVAQQPDELTLELADILNILDKTDDGWIFGERLHDQERGWFPSSMTEEILNPKIRSQNLKECFRVHKMDDPQRSQNKDRRKLGSRNRQ", "length": 710 }, "evidence": [ { "id": "HGNC:7807", "url": "https://alliancegenome.org/gene/HGNC:7807#orthology", "database": "AGR" }, { "id": "MGI:1858414", "url": "https://alliancegenome.org/gene/MGI:1858414#orthology", "database": "AGR" }, { "id": "RGD:1309055", "url": "https://alliancegenome.org/gene/RGD:1309055#orthology", "database": "AGR" }, { "id": "FB:FBgn0261547", "url": "https://alliancegenome.org/gene/FB:FBgn0261547#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q96DR7-1", "protein_name": "Rho guanine nucleotide exchange factor 26", "gene_name": "ARHGEF26", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDGESEVDFSSNSITPLWRRRSIPQPHQVLGRSKPRPQSYQSPNGLLITDFPVEDGGTLLAAQIPAQVPTASDSRTVHRSPLLLGAQRRAVANGGTASPEYRAASPRLRRPKSPKLPKAVPGGSPKSPANGAVTLPAPPPPPVLRPPRTPNAPAPCTPEEDLTGLTASPVPSPTANGLAANNDSPGSGSQSGRKAKDPERGLFPGPQKSSSEQKLPLQRLPSQENELLENPSVVLSTNSPAALKVGKQQIIPKSLASEIKISKSNNQNVEPHKRLLKVRSMVEGLGGPLGHAGEESEVDNDVDSPGSLRRGLRSTSYRRAVVSGFDFDSPTSSKKKNRMSQPVLKVVMEDKEKFSSLGRIKKKMLKGQGTFDGEENAVLYQNYKEKALDIDSDEESEPKEQKSDEKIVIHHKPLRSTWSQLSAVKRKGLSQTVSQEERKRQEAIFEVISSEHSYLLSLEILIRMFKNSKELSDTMTKTERHHLFSNITDVCEASKKFFIELEARHQNNIFIDDISDIVEKHTASTFDPYVKYCTNEVYQQRTLQKLLATNPSFKEVLSRIESHEDCRNLPMISFLILPMQRVTRLPLLMDTICQKTPKDSPKYEVCKRALKEVSKLVRLCNEGARKMERTEMMYTINSQLEFKIKPFPLVSSSRWLVKRGELTAYVEDTVLFSRRTSKQQVYFFLFNDVLIITKKKSEESYNVNDYSLRDQLLVESCDNEELNSSPGKNSSTMLYSRQSSASHLFTLTVLSNHANEKVEMLLGAETQSERARWITALGHSSGKPPADRTSLTQVEIVRSFTAKQPDELSLQVADVVLIYQRVSDGWYEGERLRDGERGWFPMECAKEITCQATIDKNVERMGRLLGLETNV", "length": 871 }, "evidence": [ { "id": "HGNC:24490", "url": "https://alliancegenome.org/gene/HGNC:24490#orthology", "database": "AGR" }, { "id": "RGD:1562559", "url": "https://alliancegenome.org/gene/RGD:1562559#orthology", "database": "AGR" }, { "id": "FB:FBgn0261547", "url": "https://alliancegenome.org/gene/FB:FBgn0261547#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "neuromuscular junction", "id": "GO:0031594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031594", "evidence": [ { "database": "UniProtKB", "id": "Q9VVC6", "url": "https://www.uniprot.org/uniprotkb/Q9VVC6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "regulation of actin cytoskeleton organization", "id": "GO:0032956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032956", "evidence": [ { "database": "UniProtKB", "id": "Q9VVC6", "url": "https://www.uniprot.org/uniprotkb/Q9VVC6" } ], "pmid": "" }, { "name": "regulation of neurotransmitter 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Classification" ] }, { "id": "PTHR24025:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24025:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001246814", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001246814", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VVG0", "url": "https://www.uniprot.org/uniprotkb/Q9VVG0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VVG0-1", "url": "https://www.uniprot.org/uniprotkb/Q9VVG0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLPLLLPLFLSLTAGQLVNQPPQFVPGTGDMSRFSLSENTPVGSPVFQLKGTDPEGGRLKYSISGPVFSVDRETGVVRLRQELDRETQDTVEVIISITDEGIYGTEPNTVSQRRVIPVRDYNDNQPTFLGRPYTASVSESLPVGSELSVEPPIVVVDRDEGINSEVQMKCLEENDICDIFEVRAVKISDGNYTARVALKQQLDFESRPSYILTISASDSALDNRLSSLATISINVIDIQDQPPIFTNAPYSATVPENTPAGVSILTVKAVDGDVGIPREIFLSLEDEPFGHFELVPFGDPRDGTAVLQTTSEPLDRENAEILQNGGVYVFSIRATELIDGAIPAEHSLTRVTIVVTDVDDHQPTFSGPHFNVSITENLANGMPLPGLSIFVDDRDMGENSRYELSLRDVFNAARVFEVSPTESQGRTPVVVKVLNASRLDYDVVDPDLRKFEFDLVASVKGVEKAKTRVEIHLLDANDNAPVFDQGTYRFTAAENLPVDAIIGHVKATDLDSGEFGHVRYVLKGFGADNFYVNPETGGVYLLKPLDYEKQSSYSLTVVAIDGGQREANANLFVGVTDVNDNHPNFESKEYSRTIREGAALFEPQFFVRAHDADGPSQGNGRVKYSIVSENSIAGNVFRIEPDTGEIVIQKAARSMDTERGEYELVVSATDFGIPPLSNTTRVLVRVGISGNQRPIFRGHFQNMENLPIIGPPSYRVSIPENAAAGSNVTSVSAHDPDGLDSLLRYRIVGANDNFEIDEISGLITVSPQARIDRDSNMNSFEIIVNAVDSGTPIPETATTTVYVNVKDINDERPKFEQNSYATYVSERTAVGESVLRVKAIDKDLNSKLEYSMVGPVAATTKAGVSIANRSNYRLQEAFRVDSQSGEIFVNGTLRHDVAAIIIFTVGVRDLNAEVDPEGQVDTTEVTVYVQSFQDTNPVFKNTGWTSSRPVIDVKIKEEMPIDSALFILQAEDPVTRQPITSFELIEPKQVDYFQVAERTGEVILKKRLDYEALGDTGPEFELQVRANSADRQRSTVSRVNITVENVNDNSPRFERNSYQATIIENRPHPERVIRVRALDKDAVLNARDERLGYHKIIYSLQGEHAMLFDINNTTGEIIVASGQTIDRERTPRIQLQIKAEDSPGRPTDAKQSVVELQIEVLDVNDNAPEFTQKKYSTVIPENAQIDSFVLQLEAVDADEGLGGEVRYELVNEGEANGLFKIDTKSGLISTRRNLTGKGRAHPYVLIVRAQDNGNQMPKQPTLSTDTDVRIYIGDVSANDGVPYFLSPRVGQMANVTENAVTGAPVFQVIASDPDDESTPSGTITYRILPDTPDAEAFVIDAHSGLITTRQSMDRETKDMYRILLEVSDNGQPKQSATRILQIAILDVDDHEPRFAREADAGPLSMSVREEEPAGTIVGNFSALDEDLGENAAIDYVIIDGNNEQLFTIERNNESLAILKTKKPIDREQVESFTLTIKCLKLGEPGYKFIGDPYDRQDLSHLRINVRVLDIDDNLPKFEQPDPTVGIRINVPIDTVVTTLKASDADAEAPPVGLSIENVTFVPQFYKRSRSLAVGNLHNLFTLNNRTGELRTGGSFADYVDGYFLMRVMANNSVQPKRQAHSNLKVFVIRDKSLLKFVFARPPNEIQHNIRPFQEQLQKKLKPLGLELHVLDTQVFTRPDMSLDFTATSSCFQMFKNGAALSFNEMQKLMNSQQLRQELIDIYAAYGVSEVESCSVRRTHAAAIFAGMLTSAGAWLVFLAALIGLAALVSLCTACCLKKKLKRHSKRSLQASLRTPTEHTATSYSYSMPAVLYSEPIYGPL", "length": 1820, "header": "tr|Q9VVG0-1|Q9VVG0_DROME Isoform 1 of Cadherin 74A, isoform C OS=Drosophila melanogaster OX=7227 GN=Cad74A PE=4 SV=1 CANONICAL=Q9VVG0-1" }, "isoforms": [ { "isoform_ac": "Q9VVG0-1", "url": "https://www.uniprot.org/uniprotkb/Q9VVG0/entry#Q9VVG0-1", "sequence": { "sequence": "MLPLLLPLFLSLTAGQLVNQPPQFVPGTGDMSRFSLSENTPVGSPVFQLKGTDPEGGRLKYSISGPVFSVDRETGVVRLRQELDRETQDTVEVIISITDEGIYGTEPNTVSQRRVIPVRDYNDNQPTFLGRPYTASVSESLPVGSELSVEPPIVVVDRDEGINSEVQMKCLEENDICDIFEVRAVKISDGNYTARVALKQQLDFESRPSYILTISASDSALDNRLSSLATISINVIDIQDQPPIFTNAPYSATVPENTPAGVSILTVKAVDGDVGIPREIFLSLEDEPFGHFELVPFGDPRDGTAVLQTTSEPLDRENAEILQNGGVYVFSIRATELIDGAIPAEHSLTRVTIVVTDVDDHQPTFSGPHFNVSITENLANGMPLPGLSIFVDDRDMGENSRYELSLRDVFNAARVFEVSPTESQGRTPVVVKVLNASRLDYDVVDPDLRKFEFDLVASVKGVEKAKTRVEIHLLDANDNAPVFDQGTYRFTAAENLPVDAIIGHVKATDLDSGEFGHVRYVLKGFGADNFYVNPETGGVYLLKPLDYEKQSSYSLTVVAIDGGQREANANLFVGVTDVNDNHPNFESKEYSRTIREGAALFEPQFFVRAHDADGPSQGNGRVKYSIVSENSIAGNVFRIEPDTGEIVIQKAARSMDTERGEYELVVSATDFGIPPLSNTTRVLVRVGISGNQRPIFRGHFQNMENLPIIGPPSYRVSIPENAAAGSNVTSVSAHDPDGLDSLLRYRIVGANDNFEIDEISGLITVSPQARIDRDSNMNSFEIIVNAVDSGTPIPETATTTVYVNVKDINDERPKFEQNSYATYVSERTAVGESVLRVKAIDKDLNSKLEYSMVGPVAATTKAGVSIANRSNYRLQEAFRVDSQSGEIFVNGTLRHDVAAIIIFTVGVRDLNAEVDPEGQVDTTEVTVYVQSFQDTNPVFKNTGWTSSRPVIDVKIKEEMPIDSALFILQAEDPVTRQPITSFELIEPKQVDYFQVAERTGEVILKKRLDYEALGDTGPEFELQVRANSADRQRSTVSRVNITVENVNDNSPRFERNSYQATIIENRPHPERVIRVRALDKDAVLNARDERLGYHKIIYSLQGEHAMLFDINNTTGEIIVASGQTIDRERTPRIQLQIKAEDSPGRPTDAKQSVVELQIEVLDVNDNAPEFTQKKYSTVIPENAQIDSFVLQLEAVDADEGLGGEVRYELVNEGEANGLFKIDTKSGLISTRRNLTGKGRAHPYVLIVRAQDNGNQMPKQPTLSTDTDVRIYIGDVSANDGVPYFLSPRVGQMANVTENAVTGAPVFQVIASDPDDESTPSGTITYRILPDTPDAEAFVIDAHSGLITTRQSMDRETKDMYRILLEVSDNGQPKQSATRILQIAILDVDDHEPRFAREADAGPLSMSVREEEPAGTIVGNFSALDEDLGENAAIDYVIIDGNNEQLFTIERNNESLAILKTKKPIDREQVESFTLTIKCLKLGEPGYKFIGDPYDRQDLSHLRINVRVLDIDDNLPKFEQPDPTVGIRINVPIDTVVTTLKASDADAEAPPVGLSIENVTFVPQFYKRSRSLAVGNLHNLFTLNNRTGELRTGGSFADYVDGYFLMRVMANNSVQPKRQAHSNLKVFVIRDKSLLKFVFARPPNEIQHNIRPFQEQLQKKLKPLGLELHVLDTQVFTRPDMSLDFTATSSCFQMFKNGAALSFNEMQKLMNSQQLRQELIDIYAAYGVSEVESCSVRRTHAAAIFAGMLTSAGAWLVFLAALIGLAALVSLCTACCLKKKLKRHSKRSLQASLRTPTEHTATSYSYSMPAVLYSEPIYGPL", "length": 1820, "header": "tr|Q9VVG0-1|Q9VVG0_DROME Isoform 1 of Cadherin 74A, isoform C OS=Drosophila melanogaster OX=7227 GN=Cad74A PE=4 SV=1 CANONICAL=Q9VVG0-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1523, "start_aa": "Thr", "end_pos": 1523, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1523", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VVG0", "url": "https://www.uniprot.org/uniprotkb/Q9VVG0" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VVG0", "url": "https://www.uniprot.org/uniprotkb/Q9VVG0" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVG0", "url": "https://www.uniprot.org/uniprotkb/Q9VVG0" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVG0", "url": "https://www.uniprot.org/uniprotkb/Q9VVG0" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VVG0", "url": "https://www.uniprot.org/uniprotkb/Q9VVG0" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VVG0", "url": "https://www.uniprot.org/uniprotkb/Q9VVG0" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VVG0", "url": "https://www.uniprot.org/uniprotkb/Q9VVG0" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVG0", "url": "https://www.uniprot.org/uniprotkb/Q9VVG0" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVG0", "url": "https://www.uniprot.org/uniprotkb/Q9VVG0" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VVG0", "url": "https://www.uniprot.org/uniprotkb/Q9VVG0" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VVG0", "url": "https://www.uniprot.org/uniprotkb/Q9VVG0" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG6445", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG6445", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZAN2-1", "protein_name": "Cadherin-related family member 2", "gene_name": "Cdhr2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAWLWLLCVLLPTFMVSVTANSLPVFESNMTLVLLPEDLPVGAVVFWLVATDPDGDQLTYGISGLHANYFSVTSNTGEVKLVSSLDFETLPSFRITISVNDGHNVQVTKEMQVIVEDRNDNAPVFLNTEFSTSIKETLPVGSVVFSVLAEDKDTGSSGLVEYFIEKVIPSTDNSKDLFRILVNGSIVLNDTLSYNNKSAFYQLELKACDSGGLLNNTLVTQCSQPVFVSISVIDEPDLDPQFVREFYSASVSEDATLGTSVLAVEAVDSDKGVNYNVTYNITNSTRPGWFCIEKDGVITVCGPLDREQLLLDNEEVQIQVTATEEKPNIYQQEAKVSTWVTIKVTDVNDHKPEFYNCSLQNCTFSPQEAQDNFTGYVDEHASARISIDGLTMVAYDPDQGANGTFLLSLNGTDAEAFNVSPERAAVSVSVQVVVKNSEMVDYEKKTEMQVQVVATDSVSGNYSVATVTIHLRNINDHRPVFSKSLYELTVPENSPTGFLVTDSIEATDLDGDEWGPITYSLLPGAGEDLFEVEPKSGNVTVKNGTLLDREKQAMYYLTMQATDGGNQSTTTMLQITLLDVNDNPPVVRGSYNIFVPEEDGDVSVTIQAYDDDQPGTNNSRLLFSLLPGSYSQNFSIDPDTGLLRNLEPLDREAIDPALEGRIVLTVHVADCGEPSLSTDVNVTITVEDINDNLPIFNQSSYEFFVMERVPGALVGTVKAWDADQTAANNRISFSLSGTGANNFILQSIVLALGWAEGHLWLLPDVSLDYETQKLFNLTVSAENPGPQGLESTANITVVVVDVNDEPPTLDAVSLQSISVAENGSEHGQVAQVIAQDVDTNALLRIELVDVLCTKAGVDVGSVCHGWFSVDTNGSVYINQSEAIDYEVCHLVTLVVRAQDLATDLGFDAYSSNGSLLINIKDKNDNTPYFLPNNQTFVIIPELVLPNQQVASVQARDEDSEDNGIIKFSILKADFVPKDGATNPVQVFRISQSVEAGLYTGSIELVTNLDSTLQGTYQVTVQAQDQPAMDPALETQTTLNLFTVDQSYRVRLQFSTSREDVGANMEEIKAALIQATRTSVYVVTIQNIDSMARARVNSYMDAYFVFSNGSALTLTELNVMIRKDQDALRQLLQLGLVVVSSQETQEFNQTQLLTNVIIGLVVSLVLVLVIMITALVCFRKSYHRKLRAMKAGKEARKTPIETMTPAAAIPGTNVYNTDRANPMLDLPTKDLGLECHSSSDLDYHSLNSLDENSVDLDTDSKEFKRKDLPHNPPESDSEPLTAALSGRSAGTSGQQQRELSFTNPGLDTTDL", "length": 1310 }, "evidence": [ { "id": "MGI:2687323", "url": "https://alliancegenome.org/gene/MGI:2687323#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9Q7P9-1", "protein_name": "Cadherin-related family member 2", "gene_name": "Cdhr2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAWLWLLCALLPAFMVSVTANSPPSFGVNMTLVTLPEDLPVGAVAFWLVATDSDNDHLTYGISGPNASYFSVNANTGEVKLASPLDFETVPFFKITISTSDGLNIRTAEMQVIVEDRNDNIPVFLNTEFSTSINETLPVGSVVFSVLAEDKDTGTAGLVQYFIEKVIPSTANSNNLFRILENGSIVLNDTLSYNNKSAFYQLELKACDSGGILDNKPKTQCSQPVFVSISVIDEPDLDPRFIREFYSASVAEDATLGTSVLTVEAVDSDKGINDIVTYSVSNSTRPGWFDIREDGVIFVNGSLDREQLLLENEEVQIQVTATEKNLNIYGQEAKASMWVTIRVTDVNDHKPEFYNCSLPGCSFSPQEAQVNFIGYVDEHASARISIDGLTMVAYDPDQGDNGTFLLSLNGQDAEAFNVSPERAAGSVSVQVVVRNSEMVDYEKETVMVVEVVATDSVSNNYSVATVTIHLRNINDHRPVFSQSLYELTVPEHCPTGYLVTDKIQATDLDGDEWGPITYSLLPGNGADLFEVEPNSGNLTVKNGTLLDREKQAVYYLTLQATDGGNQSTTTALEITLLDINDNPPVVRGSYNVFVPEENGNVSVTIQAYDDDQPDTNNSLLVFSLLPGPYSSNFSLDPNTGLLRNLGPLDREAIDPALEGRIVLTVIVADCGEPSLSTNVNVTITVEDINDNLPVFNQSYEFSVWERVPGAWVGTVKAWDADQTAANNRISFSLSGTGANNFILQGNVLEQGWAEGSLWLLPDVRLDYETQKFFHLTVSAENPGPQGLDSTANVTVTVMDVNDEPPTLDAASLQAISVTENGSEHGQVTRVIAQDVDTAALLRIELVDVICTKAGVDVGSVCHGWFSVDGNGSVYINQSEAIDYEACHLVTLVVRAYDLNTDPGFDAYSSNGSLLINIKDKNDNAPYFLPNNQTFVIIPELVLPNQQVASVQARDEDSEDNGIIMFSILKAEFVRKDGTSNPVQVFRITRSVEAGLFTGSIELVTNLDSTIQGTYQVTVQAQDQPTLGPALETQTTLNLFTVDQSYRVRLQFSTSKEDVGANMEEIKEALIQATRTSVYVVTIQNIDSTARARASSYMDAYFVFSNGTALTLTELNMMIRKDQDALRQLLQLGLVVVSSQESQEPDQQKLLTSVIIGLVVSLVLVLVILITALVCLRKSYHRKLRAMKAGKEARKTPIETTAPTAAIPGTNMYNTDRANPVLDLPTKDLGLECHSSSDLDYDSLNSLDENSVDLDMDSKEFKRKDLPGDPPEPDPEPLTAVLSGRSAGASEQQKKNLSFTNPGLDTTDL", "length": 1308 }, "evidence": [ { "id": "MGI:2687323", "url": "https://alliancegenome.org/gene/MGI:2687323#orthology", "database": "AGR" }, { "id": "FB:FBgn0036715", "url": "https://alliancegenome.org/gene/FB:FBgn0036715#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P58365-1", "protein_name": "Cadherin-23", "gene_name": "Cdh23", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRHPPVTWCAMLWLLMLVSGSWGQVNRLPFFTNHFFDTYLLISEDTPVGSSVTQLLARDMDNDPLVFGVSGEEASRFFAVEPDTGVVWLRQPLDRETKSEFTVEFSVSDHQGVITRKVNIQVGDVNDNAPTFHNQPYSVRIPENTPVGTPIFIVNATDPDLGAGGSVLYSFQPPSQFFAIDSARGIVTVIRELDYEVTQAYQLTVNATDQDKTRPLSTLANLAIIITDVQDMDPIFINLPYSTNIYEHSPPGTTVRVITAVDQDKGRPRGIGYTIVSGNTNSIFALDYISGALTLNGLLDRENPLYSHGFILTVKGTELNDDRSPSDATVTTTFNILVIDINDNAPEFNSSEYSVAITELAQVGFALPLFIQVVDKDEGLNSMFEVYLVGNNSHHFIISPTSVQGKADIRIRVAIPLDYETVDRYDFDLFANESVPDHVGYAKVKITLINENDNRPIFSQPLYNVSLYENITVGTSVLTVLATDNDVGTFGEVNYFFSDDPDRFSLDKDTGLIMLIARLDYELIQRFTLTVIARDGGGEETTGRVRINVLDVNDNVPTFQKDAYVGALRENEPSVTQLVRLRATDEDSPPNNLITYSIVNASAFGSYFDISVYEGYGVISVSRPLDYEQIPNGLIYLTVMAKDAGNPPLYSTVPVTIEVFDENDNPPTFSKPAYFVSVVENIMAGATVLFLNATDLDRSREYGQESIIYSLEGSSQFRINARSGEITTTSLLDRETKAEYILIVRAVDGGVGHNQKTGIATVNVTLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTVVAVDPDLGKNGTLVYSIQPPNKFYSLNSTTGKIRTTHVMLDRENPDPVEAELMRKIIVSVTDCGRPPLKATSSATVFVNLLDLNDNDPTFQNLPFVAEVLEGTPAGVSVYQVVAIDLDEGLNGLVSYRMQVGMPRMDFVINSTSGVVTTTAELDRERIAEYQLRVVASDAGTPTKSSTSTLTIRVLDVNDETPTFFPAVYNVSVSEDVPREFRVVWLNCTDNDVGLNAELSYFITAGNVDGKFSVGYRDAVVRTVVGLDRETTAAYTLVLEAIDNVPVGKRRTGTATVFVTVLDVNDNRPIFLQSSYEASVPEDIPEGHSIVQLKATDADEGEFGRVWYRILHGNHGNNFRLHVSSGLLVRGPRPLDRERNSSHVLMAEAYNHDLGPMRSSVRVIVYVEDVNDEAPVFTQQQYNRLGLRETAGIGTSVIVVRATDRDTGDGGLVNYRILSGAEGKFEIDESTGLIVTVDYLDYETKTSYLMNVSATDGAPPFNQGFCSVYVTLLNELDEAVQFSNASYEAVIMENLALGTEIVRVQAYSIDNLNQITYRFDAYTSAQAKALFKIDAITGVITVKGLVDREKGDFYTLTVVADDGGPKVDSTVKVYVTVLDENDNSPRFDFTSDSAISVPEDCPVGQRVATVKARDPDAGSNGQVVFSLASGNIAGAFEIITSNDSIGEVFVAKPLDREELDHYILKIVASDRGTPPRKKDHILQVTILDVNDNPPVIESPFGYNVSVNENVGGGTSVVQVRATDRDIGINSVLSYYITEGNEDMTFRMDRISGEIATRPAPPDRERQNFYHLVVTVEDEGTPTLSATTHVYVTIVDENDNAPVFQQPHYEVVLDEGPDTVNTSLITVQALDLDEGPNGTVTYAIVAGNIINTFRINRRTGVITAAKELDYEISHGRYTLIVTATDQCPILSHRLTSTTTVLVNVNDINDNVPTFPRDYEGPFDVTEGQPGPRVWTFLAHDRDSGPNGQVEYSVVDGDPLGEFVISPVEGVLRVRKDVELDRETIAFYNLTICARDRGVPPLSSTMLVGIRVLDINDNDPVLLNLPMNITISENSPVSSFVAHVLASDADSGCNALLTFNITAGNRERAFFINATTGIVTVNRPLDRERIPEYRLTVSVKDNPENPRIARKDFDLLLVSLADENDNHPLFTEGTYQAEVMENSPAGTPLTVLNGPILALDADEDVYAVVTYQLLGTHSDLFVIDNSTGVVTVRSGVIIDREAFSPPFLELLLLAEDVGQLNGTAYLFITILDDNDNWPTFSPPAYTVHLLENCPPGFSVLQITATDEDSGLNGELVYRIEAGAQDRFLIHPVTGVIRVGNATIDREEQESYRLTVVATDRGTVPLSGTATVTILIDDINDSRPEFLNPIQTVSVLESTEPGTVIANVTAIDLDLNPKLEYHILSIVAKDDTDRLVPDQEDAFAVNINTGSVIVKSPLNRELVATYEVTLSVIDNASDLPERSVSVPNAKLTVNILDVNDNTPQFKPFGITYYTERVLEGATPGTTLIAVAAVDPDKGLNGLITYTLLDLIPPGYVQLEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPIFDQLSYQEAVFEDVAVGTVILRVTATDADSGNFALIEYSLVDGEGKFAINPNTGDIYVLSSLDREKKDHYILTALAKDNPGDVASNRRENSVQVVIRVLDVNDCRPQFSKPQFSTSVYENEPAGTSVITMLATDQDEGSNGQLTYSLEGPGMEAFSVDMDSGLVTTQRPLQSYERFNLTVVATDGGEPPLWGTTMLLVEVIDVNDNRPVFVRPPNGTILHIKEEIPLRSNVYEVYATDKDEGLNGAVRYSFLKSTGNRDWEYFTIDPISGLIQTAQRLDREKQAVYSLILVASDLGQPVPYETMQPLQVALEDIDDNEPLFVRPPKGSPQYQLLTVPEHSPRGTLVGNVTGAVDADEGPNAIVYYFIAAGNEDKNFHLQPDGRLLVLRDLDRETEAIFSFIVKASSNRSWTPPRGPSPALDLLTDLTLQEVRVVLEDINDQPPRFTKAEYTAGVATDAKVGSELIQVLALDADIGNNSLVFYGILAIHYFRALANDSEDVGQVFTMGSVDGILRTFDLFMAYSPGYFVVDIVARDLAGHNDTAIIGIYILRDDQRVKIVINEIPDRVRGFEEEFIRLLSNITGAIVNTDDVQFHVDMKGRVNFAQTELLIHVVNRDTNRILDVDRVIQMIDENKEQLRNLFRNYNVLDVQPAISVQLPDDMSALQMAIIVLAILLFLAAMLFVLMNWYYRTIHKRKLKAIVAGSAGNRGFIDIMDMPNTNKYSFDGANPVWLDPFCRNLELAAQAEHEDDLPENLSEIADLWNSPTRTHGTFGREPAAVKPEDDRYLRAAIQEYDNIAKLGQIIREGPIKLIHTDLEEEPGDHSPGQGSLRFRHKPPTELKGPDGIHIVHGSTGTLLATDLNSLPEDDQKGLDRSLETLTASEATAFERNARTESAKSTPLHKLRDVIMESPLEITEL", "length": 3317 }, "evidence": [ { "id": "RGD:619760", "url": "https://alliancegenome.org/gene/RGD:619760#orthology", "database": "AGR" }, { "id": "FB:FBgn0036715", "url": "https://alliancegenome.org/gene/FB:FBgn0036715#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6B3P0-1", "protein_name": "Cadherin-related family member 1a", "gene_name": "cdhr1a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKNAREIQFSSFLLLAHFCFVGAQSDYAPYFYDNGPNSNNGNMALLNLSEDTPRGTQIYVLNGTDPEGQPVKYGITFEPGSKEFFRVHPKSGVVTLIEDLDREAQDEIEVFVSISDSLNKVVEKVSVFIMDANDERPQFQNMPSIVDVPENTTSGSSIYKVQAVDRDTGSGGSVTYFLQSSEQSPKFAIDHHSGVLRIKPGESLDYEKSRTHFITVVAKDGGGIYKGKQQVMSSSATLTINVIDTQDSPPIFIGTPYFGYVYEVSSPGSEIFTVSAKDGDMDNPNTIIYSLDSGADGSFSINKTSGVITLNLYPADLRREVFNIKVKALEISPEGKRLDFATTTVTIRVVDLNNHPPTFYGENGPQNVFELTMYEHPQEGEFLRGLKITVNDSDQGSNAKFNLRLVGPGRMLRVVPQTVLNEAQVTVLVEDSAAMDFEKSQFLTFKLLAVEIDTPERFSATADIIIHLLDTNDNAPKFTSDFYIARIPENSPGGSNVVSVTAMDPDSGIWGVVKYSIYGSGADIFLIQADSGIIYTQPWASLDAEVKSKYNFYVKAEDPEGKYSLAEVFVTITDLNDHPPAFNENSLEQTMVIGAPVKIEAIDEDAEEPNNLIEYSIMKADPDNIFDINADTGEIKLKPYIKSMDIVQNITNQRDCTWSVVVQAKDRGSPSFSTTTVVKIDITEATPLKGPLTSFFMNSRENPMHFLGLISGVILILVFVTVIISTVIFVRRNKANRILPSRRIIRKKRKPQKQDDFQEPFREEQEIPRADNVNFNNNIKVCSHRTPPSPPNAPVMPPPLPSHCRHGEREWTVPTVSASVASKSKKKSHRCKDNPVNTALVSELKLKLEQKNMANRY", "length": 857 }, "evidence": [ { "id": "HGNC:14550", "url": "https://alliancegenome.org/gene/HGNC:14550#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040924-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040924-4#orthology", "database": "AGR" }, { "id": "RGD:620420", "url": "https://alliancegenome.org/gene/RGD:620420#orthology", "database": "AGR" }, { "id": "FB:FBgn0036715", "url": "https://alliancegenome.org/gene/FB:FBgn0036715#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8VHP6-1", "protein_name": "Cadherin-related family member 1", "gene_name": "Cdhr1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRRGPRVALVLGLLRIYLAQANFAPHFFDNGVGSTNGNMALFSLPEDTPVGSHVYTLNGTDPEGDPISYHISFDPSTRSVFSVDPNFGNITLVEELDREREDEIEAIISISDGLNLVAEKVVILVTDANDEAPRFIQEPYIIRVPENIPAGSSIFKVQAEDKDTGSGGSVTYSLQNLHSSKFSMDRHSGVLRLQAGATLDYEKSRAHYITVIAKDGGGRLRGADMVFSATTTVTINVEDVQDTAPIFVGTPYYGYVYEDTLPGSEVLTVVAIDGDRGKPNHILYRLLNESDGIFEINETSGAISVLQSPALLRREVYELHVQVTEVNSPGSPAAQATVPVTIRIVDLNNHPPTFYGESGPQNKFELSMFEHPPQGEILRGLKITVNDSDQGANAKFNLRLVGPGGIFRVVPQTVLNEAQVTIIVENSAAIDFEKSKLLTFKLLAIEVNTPEKFSSTADIVIQLLDTNDNVPKFTSHYYIARIPENAPGGSNVVAVTAVDPDTGPWGKVHYSIYGTGSDLFLIHPSTGLIYTQPWASLDAEGTSRYNFYVKAEDMDGRYSLAEVFVTLLDVNDHYPQFVQSVQEKTMVLGTPLKIEATDQDAEEPNNLVDYSITRAEPVNVFDIDAHTGEIRLKNSIRSLEALHNITPSGDYSWSLQVQAKDRGSPSFSTTALLKIDITDTERLSRGSMAAFLIQTKDNPMKAVGVLAGVMAIVVAITVLISTATFWRNKKSNKVLPVRRVLRRRPSPAPHTVRIEWLKFRRAKAATKFILKEDSPNENCNNSRVGVMVPPRAPALPPPPKMASSMVAQQTVPTVSGSLTPQPSPQLPTPKTLGGPVQSSLVSELKQKFEKKSLDNKAYI", "length": 859 }, "evidence": [ { "id": "HGNC:14550", "url": "https://alliancegenome.org/gene/HGNC:14550#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040924-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040924-4#orthology", "database": "AGR" }, { "id": "RGD:620420", "url": "https://alliancegenome.org/gene/RGD:620420#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q91XU7-1", "protein_name": "Cadherin-related family member 1", "gene_name": "Cdhr1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRRGPQVALVLGLLCIYLAQANFAPHFFDNGVGSTNGNMALFSLPEDTPVGSHVYTLNGTDPEGDPISYHISFDPSTRSVFSVDPNFGNITLVEELDREREDEIEAIISISDGLNLVAEKVVIVVTDANDEAPRFLQEPYNILVPENTPAGSSIFKVQAEDKDTGSGGSVTYFLQSLHSSKFTVDRHSGVLRLQAGATLDYEKSRAHFITVVAKDGGGRLRGADVVFSATTTVTINVEDVQDTAPIFVGTPYYGYVYEDTLPGSEVLTVVAIDGDRGKPNHILYRLLNESDGLFEINETSGAISVLQSPAQLRREVYELHVQVTEVNSSGSPAAQSTVPVIIRIVDLNNHPPTFYGESGPQNKFELSMFEHPPQGEILRGLKITVNDSDQGANAKFNLRLVGPGGIFRVVPQTVLNEAQVTIIVENSAAIDFEKSKSLTFKLLAIEVNTPEKFSSTADIVIQLLDTNDNVPKFTSHYYIARIPENVPGGSNVVAVTAVDPDTGPWGKVQYSIYGTGSDLFLIHPSTGLIYTQPWASLDAEGTSRYNFYVKAEDMDGRYSLAEVFVTLLDVNDHYPQFVQSVQEKTMVLGTPLKIEATDQDAEEPNNLVDYSITRAEPVNVFDIDAHTGEIRLKNSIRSLEALHNITPSGEYSWSLQVQAKDRGSPSFSTTALLKIDITDTERLSRSSMAAFLIQTKDNPMKAVGVLAGVMAIVVAITVLISTATFWRNKKSNKVLPVRRVLRRRPSPAPHTVRIEWLKFRRAKAASKFILKEDPPNENCNNSRVGVTVPPRAPALPPPPKMASSTVAQQTVPTVSGSLTPQPSQQLPTPKPLGGPAQSSLVSELKQKFEKKSLGNKAYV", "length": 859 }, "evidence": [ { "id": "HGNC:14550", "url": "https://alliancegenome.org/gene/HGNC:14550#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040924-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040924-4#orthology", "database": "AGR" }, { "id": "RGD:620420", "url": "https://alliancegenome.org/gene/RGD:620420#orthology", "database": "AGR" }, { "id": "FB:FBgn0036715", "url": "https://alliancegenome.org/gene/FB:FBgn0036715#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96JP9-1", "protein_name": "Cadherin-related family member 1", "gene_name": "CDHR1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRRCRWAALALGLLRLCLAQANFAPHFFDNGVGSTNGNMALFSLPEDTPVGSHVYTLNGTDPEGDPISYHISFDPSTRSVFSVDPTFGNITLVEELDREREDEIEAIISISDGLNLVAEKVVILVTDANDEAPRFIQEPYVALVPEDIPAGSIIFKVHAVDRDTGSGGSVTYFLQNLHSPFAVDRHSGVLRLQAGATLDYERSRTHYITVVAKDGGGRLHGADVVFSATTTVTVNVEDVQDMAPVFVGTPYYGYVYEDTLPGSEVLKVVAMDGDRGKPNRILYSLVNGNDGAFEINETSGAISITQSPAQLQREVYELHVQVTEMSPAGSPAAQATVPVTIRIVDLNNHPPTFYGESGPQNRFELSMNEHPPQGEILRGLKITVNDSDQGANAKFNLQLVGPRGIFRVVPQTVLNEAQVTIIVENSAAIDFEKSKVLTFKLLAVEVNTPEKFSSTADVVIQLLDTNDNVPKFDSLYYVARIPENAPGGSSVVAVTAVDPDTGPWGEVKYSTYGTGADLFLIHPSTGLIYTQPWASLDAEATARYNFYVKAEDMEGKYSVAEVFITLLDVNDHPPQFGKSVQKKTMVLGTPVKIEAIDEDAEEPNNLVDYSITHAEPANVFDINSHTGEIWLKNSIRSLDALHNITPGRDCLWSLEVQAKDRGSPSFSTTALLKIDITDAETLSRSPMAAFLIQTKDNPMKAVGVLAGTMATVVAITVLISTATFWRNKKSNKVLPMRRVLRKRPSPAPRTIRIEWLKSKSTKAATKFMLKEKPPNENCNNNSPESSLLPRAPALPPPPSVAPSTGAAQWTVPTVSGSLTPQPTQPPPKPKTMGSPVQSTLISELKQKFEKKSVHNKAYF", "length": 859 }, "evidence": [ { "id": "HGNC:14550", "url": "https://alliancegenome.org/gene/HGNC:14550#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040924-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040924-4#orthology", "database": "AGR" }, { "id": "RGD:620420", "url": "https://alliancegenome.org/gene/RGD:620420#orthology", "database": "AGR" }, { "id": "FB:FBgn0036715", "url": "https://alliancegenome.org/gene/FB:FBgn0036715#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99PF4-1", "protein_name": "Cadherin-23", "gene_name": "Cdh23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRYSLVTCYAVLWLLMLVPGSWGQVNRLPFFTNHFFDTYLLISEDTPVGSSVTQLLARDMDNDPLVFGVSGEEASRFFAVEPDTGVVWLRQPLDRETKSEFTVEFSVSDHQGVITRKVNIQVGDVNDNAPTFHNQPYSVRIPENTPVGTPIFIVNATDPDLGAGGSVLYSFQPPSPFFAIDSARGIVTVIQELDYEVTQAYQLTVNATDQDKTRPLSTLANLAIIITDMQDMDPIFINLPYSTNIYEHSPPGTTVRVITAVDQDKGRPRGIGYTIVSGNTNSIFALDYISGALTLNGLLDRENPLYSHGFILTVKGTELNDDRTPSDATVTTTFNILVIDINDNAPEFNSSEYSVAITELAQVGFALPLFIQVVDKDEDLGLNSMFEVYLVGNNSHHFIISPTSVQGKADIRIRVAIPLDYETVDRYDFDLFANESVPDHVGYAKVKITLINENDNRPIFSQPLYNVSLYENITVGTSVLTVLATDNDVGTFGEVNYFFSDDPDRFSLDKDTGLIMLIARLDYELIQRFTLTVIARDGGGEETTGRVRINVLDVNDNVPTFQKDAYVGALRENEPSVTQLVRLRATDEDSPPNNLITYSIVNASAFGSYFDISIYEGYGVISVSRPLDYEQIPNGLIYLTVMAKDAGNPPLYSTVPVTIEVFDENDNPPTFSKPAYFVSVLENIMAGATVLFLNATDLDRSREYGQESIIYSLEGSSQFRINARSGEITTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNVTLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTVVAVDPDLGENGTLVYSIHPPNKFYSLNSTTGKIRTTHVMLDRENPDPVEAELMRKIIVSVTDCGRPPLKATSSATVFVNLLDLNDNDPTFRNLPFVAEILEGTPAGVSVYQVVAIDLDEGLNGLVSYRMQVGMPRMDFVINSTSGVVTTTAELDRERIAEYQLRVVASDAGTPTKSSTSTLTVRVLDVNDETPTFFPAVYNVSVSEDVPREFRVVWLNCTDNDVGLNAELSYFITAGNVDGKFSVGYRDAVVRTVVGLDRETTAAYTLVLEAIDNGPVGKRRTGTATVFVTVLDVNDNRPIFLQSSYEASVPEDIPEGHSIVQLKATDADEGEFGRVWYRILHGNHGNNFRIHVGSGLLMRGPRPLDRERNSSHVLMVEAYNHDLGPMRSSVRVIVYVEDVNDEAPVFTQQQYNRLGLRETAGIGTSVIVVRATDKDTGDGGLVNYRILSGAEGKFEIDESTGLIVTVDYLDYETKTSYLMNVSATDGAPPFNQGFCSVYVTLLNELDEAVQFSNASYEAVIMENLALGTEIVRVQAYSIDNLNQITYRFDAYTSAQAKALFKIDAITGVITVKGLVDREKGDFYTLTVVADDGGPKVDSTVKVYITVLDENDNSPRFDFTSDSAISVPEDCPVGQRVATVKARDPDAGSNGQVVFSLASGNIAGAFEIITSNDSIGEVFVAKPLDREELDHYILKVVASDRGTPPRKKDHILQVTILDVNDNPPVIESPFGYNVSVNENVGGGTSVVQVRATDRDIGINSVLSYYITEGNEDMTFRMDRISGEIATRPAPPDRERQNFYHLVVTVEDEGTPTLSATTHVYVTIVDENDNAPVFQQPHYEVVLDEGPDTINTSLITVQALDLDEGPNGTVTYAIVAGNIINTFRINKHTGVITAAKELDYEISHGRYTLIVTATDQCPILSHRLTSTTTVLVNVNDINDNVPTFPRDYEGPFDVTEGQPGPRVWTFLAHDRDSGPNGQVEYSVVDGDPLGEFVISPVEGVLRVRKDVELDRETIAFYNLTICARDRGVPPLSSTMLVGIRVLDINDNDPVLLNLPMNVTISENSPVSSFVAHVLASDADSGCNALLTFNITAGNRERAFFINATTGIVTVNRPLDRERIPEYRLTVSVKDNPENPRIARKDFDLLLVSLADENDNHPLFTEGTYQAEVMENSPAGTPLTVLNGPILALDADEDVYAVVTYQLLGTHSDLFVIDNSTGVVTVRSGIIIDREAFSPPFLELLLLAEDIGQLNGTAHLFITILDDNDNWPTFSPPTYTVHLLENCPPGFSVLQVTATDEDSGLNGELVYRIEAGAQDRFLIHPVTGVIRVGNATIDREEQESYRLTVVATDRGTVPLSGTAIVTILIDDINDSRPEFLNPIQTVSVLESAEPGTIIANVTAIDLDLNPKLEYHIISIVAKDDTDRLVPDQEDAFAVNINTGSVMVKSPLNRELVATYEVTLSVIDNASDLPEHSVSVPNAKLTVNILDVNDNTPQFKPFGITYYTERVLEGATPGTTLIAVAAVDPDKGLNGLITYTLLDLTPPGYVQLEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPIFDQPSYQEAVFEDIAVGTVILRVTATDADSGNFALIEYSLVDGEGKFAINPNTGDISVLSSLDREKKDHYILTALAKDNPGDVASNRRENSVQVVIRVLDVNDCRPQFSKPQFSTSVYENEPAGTSVITMLATDQDEGSNSQLTYSLEGPGMEAFSVDMDSGLVTTQRPLQSYERFNLTVVATDGGEPPLWGTTMLLVEVIDVNDNRPVFVRPPNGTILHIKEEIPLRSNVYEVYATDNDEGLNGAVRYSFLKTTGNRDWEYFTIDPISGLIQTAQRLDREKQAVYSLILVASDLGQPVPYETMQPLQVALEDIDDNEPLFVRPPKGSPQYQLLTVPEHSPRGTLVGNVTGAVDADEGPNAIVYYFIAAGDEDKNFHLQPDGRLLVLRDLDRETEATFSFIVKASSNRSWTPPRGPSPALDLLTDLTLQEVRVVLEDINDQPPRFTKAEYTAGVATDAKVGSELIQVLALDADIGNNSLVFYGILAIHYFRALANDSEDVGQVFTMGSVDGILRTFDLFMAYSPGYFVVDIVARDLAGHNDTAIIGIYILRDDQRVKIVINEIPDRVRGFEEEFIRLLSNITGAIVNTDDVQFHVDMKGRVNFAQTELLIHVVNRDTNRILDVDRVIQMIDENKEQLRNLFRNYNVLDVQPAISVQLPDDMSALQMAIIVLAILLFLAAMLFVLMNWYYRTIHKRKLKAIVAGSAGNRGFIDIMDMPNTNKYSFDGSNPVWLDPFCRNLELAAQAEHEDDLPENLSEIADLWNSPTRTHGTFGREPAAVKPDDDRYLRAAIQEYDNIAKLGQIIREGPIKGSLLKVVLEDYLRLKKLFAQRMVQKASSCHSSISELIHTDLEEEPGDHSPGQGSLRFRHKPPMELKGQDGIHMVHGSTGTLLATDLNSLPEDDQKGLDRSLETLTASEATAFERNARTESAKSTPLHKLRDVIMESPLEITEL", "length": 3354 }, "evidence": [ { "id": "RGD:619760", "url": "https://alliancegenome.org/gene/RGD:619760#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BYE9-1", "protein_name": "Cadherin-related family member 2", "gene_name": "CDHR2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQLWLSCFLLPALVVSVAANVAPKFLANMTSVILPEDLPVGAQAFWLVAEDQDNDPLTYGMSGPNAYFFAVTPKTGEVKLASALDYETLYTFKVTISVSDPYIQVQREMLVIVEDRNDNAPVFQNTAFSTSINETLPVGSVVFSVLAVDKDMGSAGMVVYSIEKVIPSTGDSEHLFRILANGSIVLNGSLSYNNKSAFYQLELKACDLGGMYHNTFTIQCSLPVFLSISVVDQPDLDPQFVREFYSASVAEDAAKGTSVLTVEAVDGDKGINDPVIYSISYSTRPGWFDIGADGVIRVNGSLDREQLLEADEEVQLQVTATETHLNIYGQEAKVSIWVTVRVMDVNDHKPEFYNCSLPACTFTPEEAQVNFTGYVDEHASPRIPIDDLTMVVYDPDKGSNGTFLLSLGGPDAEAFSVSPERAVGSASVQVLVRVSALVDYERQTAMAVQVVATDSVSQNFSVAMVTIHLRDINDHRPTFPQSLYVLTVPEHSATGSVVTDSIHATDPDTGAWGQITYSLLPGNGADLFQVDPVSGTVTVRNGELLDRESQAVYYLTLQATDGGNLSSSTTLQIHLLDINDNAPVVSGSYNIFVQEEEGNVSVTIQAHDNDEPGTNNSRLLFNLLPGPYSHNFSLDPDTGLLRNLGPLDREAIDPALEGRIVLTVLVSDCGEPVLGTKVNVTITVEDINDNLPIFNQSSYNFTVKEEDPGVLVGVVKAWDADQTEANNRISFSLSGSGANYFMIRGLVLGAGWAEGYLRLPPDVSLDYETQPVFNLTVSAENPDPQGGETIVDVCVNVKDVNDNPPTLDVASLRGIRVAENGSQHGQVAVVVASDVDTSAQLEIQLVNILCTKAGVDVGSLCWGWFSVAANGSVYINQSKAIDYEACDLVTLVVRACDLATDPGFQAYSNNGSLLITIEDVNDNAPYFLPENKTFVIIPELVLPNREVASVRARDDDSGNNGVILFSILRVDFISKDGATIPFQGVFSIFTSSEADVFAGSIQPVTSLDSTLQGTYQVTVQARDRPSLGPFLEATTTLNLFTVDQSYRSRLQFSTPKEEVGANRQAINAALTQATRTTVYIVDIQDIDSAARARPHSYLDAYFVFPNGSALTLDELSVMIRNDQDSLTQLLQLGLVVLGSQESQESDLSKQLISVIIGLGVALLLVLVIMTMAFVCVRKSYNRKLQAMKAAKEARKTAAGVMPSAPAIPGTNMYNTERANPMLNLPNKDLGLEYLSPSNDLDSVSVNSLDDNSVDVDKNSQEIKEHRPPHTPPEPDPEPLSVVLLGRQAGASGQLEGPSYTNAGLDTTDL", "length": 1310 }, "evidence": [ { "id": "MGI:2687323", "url": "https://alliancegenome.org/gene/MGI:2687323#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9H251-1", "protein_name": "Cadherin-23", "gene_name": "CDH23", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGRHVATSCHVAWLLVLISGCWGQVNRLPFFTNHFFDTYLLISEDTPVGSSVTQLLAQDMDNDPLVFGVSGEEASRFFAVEPDTGVVWLRQPLDRETKSEFTVEFSVSDHQGVITRKVNIQVGDVNDNAPTFHNQPYSVRIPENTPVGTPIFIVNATDPDLGAGGSVLYSFQPPSQFFAIDSARGIVTVIRELDYETTQAYQLTVNATDQDKTRPLSTLANLAIIITDVQDMDPIFINLPYSTNIYEHSPPGTTVRIITAIDQDKGRPRGIGYTIVSGNTNSIFALDYISGVLTLNGLLDRENPLYSHGFILTVKGTELNDDRTPSDATVTTTFNILVIDINDNAPEFNSSEYSVAITELAQVGFALPLFIQVVDKDENLGLNSMFEVYLVGNNSHHFIISPTSVQGKADIRIRVAIPLDYETVDRYDFDLFANESVPDHVGYAKVKITLINENDNRPIFSQPLYNISLYENVTVGTSVLTVLATDNDAGTFGEVSYFFSDDPDRFSLDKDTGLIMLIARLDYELIQRFTLTIIARDGGGEETTGRVRINVLDVNDNVPTFQKDAYVGALRENEPSVTQLVRLRATDEDSPPNNQITYSIVSASAFGSYFDISLYEGYGVISVSRPLDYEQISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDENDNPPTFSKPAYFVSVVENIMAGATVLFLNATDLDRSREYGQESIIYSLEGSTQFRINARSGEITTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNITLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTVVAVDPDLGENGTLVYSIQPPNKFYSLNSTTGKIRTTHAMLDRENPDPHEAELMRKIVVSVTDCGRPPLKATSSATVFVNLLDLNDNDPTFQNLPFVAEVLEGIPAGVSIYQVVAIDLDEGLNGLVSYRMPVGMPRMDFLINSSSGVVVTTTELDRERIAEYQLRVVASDAGTPTKSSTSTLTIHVLDVNDETPTFFPAVYNVSVSEDVPREFRVVWLNCTDNDVGLNAELSYFITGGNVDGKFSVGYRDAVVRTVVGLDRETTAAYMLILEAIDNGPVGKRHTGTATVFVTVLDVNDNRPIFLQSSYEASVPEDIPEGHSILQLKATDADEGEFGRVWYRILHGNHGNNFRIHVSNGLLMRGPRPLDRERNSSHVLIVEAYNHDLGPMRSSVRVIVYVEDINDEAPVFTQQQYSRLGLRETAGIGTSVIVVQATDRDSGDGGLVNYRILSGAEGKFEIDESTGLIITVNYLDYETKTSYMMNVSATDQAPPFNQGFCSVYITLLNELDEAVQFSNASYEAAILENLALGTEIVRVQAYSIDNLNQITYRFNAYTSTQAKALFKIDAITGVITVQGLVDREKGDFYTLTVVADDGGPKVDSTVKVYITVLDENDNSPRFDFTSDSAVSIPEDCPVGQRVATVKAWDPDAGSNGQVVFSLASGNIAGAFEIVTTNDSIGEVFVARPLDREELDHYILQVVASDRGTPPRKKDHILQVTILDINDNPPVIESPFGYNVSVNENVGGGTAVVQVRATDRDIGINSVLSYYITEGNKDMAFRMDRISGEIATRPAPPDRERQSFYHLVATVEDEGTPTLSATTHVYVTIVDENDNAPMFQQPHYEVLLDEGPDTLNTSLITIQALDLDEGPNGTVTYAIVAGNIVNTFRIDRHMGVITAAKELDYEISHGRYTLIVTATDQCPILSHRLTSTTTVLVNVNDINDNVPTFPRDYEGPFEVTEGQPGPRVWTFLAHDRDSGPNGQVEYSIMDGDPLGEFVISPVEGVLRVRKDVELDRETIAFYNLTICARDRGMPPLSSTMLVGIRVLDINDNDPVLLNLPMNITISENSPVSSFVAHVLASDADSGCNARLTFNITAGNRERAFFINATTGIVTVNRPLDRERIPEYKLTISVKDNPENPRIARRDYDLLLIFLSDENDNHPLFTKSTYQAEVMENSPAGTPLTVLNGPILALDADQDIYAVVTYQLLGAQSGLFDINSSTGVVTVRSGVIIDREAFSPPILELLLLAEDIGLLNSTAHLLITILDDNDNRPTFSPATLTVHLLENCPPGFSVLQVTATDEDSGLNGELVYRIEAGAQDRFLIHLVTGVIRVGNATIDREEQESYRLTVVATDRGTVPLSGTAIVTILIDDINDSRPEFLNPIQTVSVLESAEPGTVIANITAIDHDLNPKLEYHIVGIVAKDDTDRLVPNQEDAFAVNINTGSVMVKSPMNRELVATYEVTLSVIDNASDLPERSVSVPNAKLTVNVLDVNDNTPQFKPFGITYYMERILEGATPGTTLIAVAAVDPDKGLNGLVTYTLLDLVPPGYVQLEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPIFDQPSYQEAVFEDVPVGTIILTVTATDADSGNFALIEYSLGDGESKFAINPTTGDIYVLSSLDREKKDHYILTALAKDNPGDVASNRRENSVQVVIQVLDVNDCRPQFSKPQFSTSVYENEPAGTSVITMMATDQDEGPNGELTYSLEGPGVEAFHVDMDSGLVTTQRPLQSYEKFSLTVVATDGGEPPLWGTTMLLVEVIDVNDNRPVFVRPPNGTILHIREEIPLRSNVYEVYATDKDEGLNGAVRYSFLKTAGNRDWEFFIIDPISGLIQTAQRLDRESQAVYSLILVASDLGQPVPYETMQPLQVALEDIDDNEPLFVRPPKGSPQYQLLTVPEHSPRGTLVGNVTGAVDADEGPNAIVYYFIAAGNEEKNFHLQPDGCLLVLRDLDREREAIFSFIVKASSNRSWTPPRGPSPTLDLVADLTLQEVRVVLEDINDQPPRFTKAEYTAGVATDAKVGSELIQVLALDADIGNNSLVFYSILAIHYFRALANDSEDVGQVFTMGSMDGILRTFDLFMAYSPGYFVVDIVARDLAGHNDTAIIGIYILRDDQRVKIVINEIPDRVRGFEEEFIHLLSNITGAIVNTDNVQFHVDKKGRVNFAQTELLIHVVNRDTNRILDVDRVIQMIDENKEQLRNLFRNYNVLDVQPAISVRLPDDMSALQMAIIVLAILLFLAAMLFVLMNWYYRTVHKRKLKAIVAGSAGNRGFIDIMDMPNTNKYSFDGANPVWLDPFCRNLELAAQAEHEDDLPENLSEIADLWNSPTRTHGTFGREPAAVKPDDDRYLRAAIQEYDNIAKLGQIIREGPIKGSLLKVVLEDYLRLKKLFAQRMVQKASSCHSSISELIQTELDEEPGDHSPGQGSLRFRHKPPVELKGPDGIHVVHGSTGTLLATDLNSLPEEDQKGLGRSLETLTAAEATAFERNARTESAKSTPLHKLRDVIMETPLEITEL", "length": 3354 }, "evidence": [ { "id": "RGD:619760", "url": "https://alliancegenome.org/gene/RGD:619760#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VFH5-1", "protein_name": "Cadherin 88C", "gene_name": "Cad88C", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MHNESQPPANGNGIDSMDYKKVRLKGQRRRSFSSYISSISIQVIILTTLISLVASNRPPRFAIDGQSEIVLRLKESPETKVGTLIYTLKGYDPDNDPLTFGKRNSHDSEIIRIENTGGNEAKIFLAKELDRELQDEYAIVLTLTDSHYSDHNYVTQSFLLLVEDINDNVPTFLPYQNAIEIPEGSAPGVVSTLEATDADEGAYGQVVYYLQELDGDNDVFSIATHQGKGILRLQKELDYERKSLYQLRVLAIDRANQGPINTGTAAILVKVKDLEDQPPEFVEVQAVARIAEDAPVGTKVLRVRAIDGDRGINNPIAYSLEANDLFDINPHTGIVHTLTKLDREEQSDQVNGAHILRISATELSKSNTQMAPTTVRTEVTVIVSDVNDEIPTFGETVYRCEVNENAQTNTPLNFIDEEVQNVVFDHDEGNNGTFRLFLDPPNDLFEIVPELAVNEANFMLRVKNSKSLDFEQFTEVNFTIFAREVDEPSRWSSAHVQIFIRDQNDNFPEFSQTIYNASVLENSEQDTIITHVQAVDVDSGDYGTMGIRYTNLRGGIAHLLNLNPITGVITIKQAGGTAFDREIISRHYLTVEAIDNAGQGNRNTAQIIVDILDVNDNAPTFPQRQYETKLLENQAEFETPLQLEARDADLNGTENSQVTYEIVEGLYRSNFTIDPQSGLLRPVHSFDFEELVDGSSRRSDPYTGGSFSIREIDLLVRARDSGIPMLSTVVPVLIYVQDVNDNAPIFQQSFYAKTVPEDLPGGSSVLQVTAIDRDGSAPNNVVVYRIQTGAGDKFIINSETGVISVAHGANLDPDLTESKRSLYTLSVIALDGGLGNSQLMTTCTVNISIQDVNNKPPVLKEMPALQILENTPVGTLVYRIQATDLDHKAILRYKLNPEHCEGRTEEGALVKSSEYDFLGAFEVDSIEGTLKVVKLLDRERVEHIKLAITVEDLAAAKGRQIAEGFLSIQVLDENDNNPKFRLPFYRQSITENSINGAMIVNVLASDVDKNRTITYALEGNPTYRSLMHLDPQTGEIVVASKIDHEQHQWLNFSVRATDSGIPARSSLVDVYITVLDENDNNPYFVGGSKNYTISENAAPGTRVATLQAGDADSGDFGKITFLMDRISSQGKFTIDADTGVLTVADRLDRESKDSYNLVIEAWDNYQFGFLAGESRNAFKQVFISILDENDNPPEVDLPMSCVLITEYHELHERVASIVGKDADDPTTPNGRLDFAITRGNKDGMFELRQIDAWNAQIFASKSLRNRYGNYSLTITTRDMGLPANIVHNTLDICVSDFNDHAPVFVRPLHNTTVRIPENATVGTLILQAYASDGDMGQNALVRYRLKPDPLGSYKMFEVDGSTGELFLKEQLNREKQKIHEIRIEAYDQGLPTSLSSDLDLTIYVRNVNDYEPQFMVNEISVNFTEHSDPGSERIKLPDTIDKDQLELDDPNDTPSQVCYFIVNGNEAGYFRLDPETHILTVDRELDREVIANFTLYVRATENCRNDSISGGEKRRRMGIEINNRLGGIVHNQQFGYDRFKHSRQLRSTESNEYGPEDAELLSYEAYDSSQEDPTGGLATTHPELDSTVIKVKVRVLDINDNPPRFRSKIFTGGITTNADFGLKFMRVEATDADEGDNGRIGYYQVGEIRQTLSEGLENVRKAPFLLDQETGEVQLNFDPQKGMKGYFDFVVLANDTSGMKDVAHVFIYLLREDQKVRFVFRLQPDELRSRVDSFRDTLSNITESIVNIDEIKVHENKDGSVDKTKTDLYMHLVEREDNSIYEVSEVLKLIDSHIESLNGLFKELNVLDTQAAEAQLLTAGPSRGPLFVWLIFTNLFLATLLVVTIALCASQRNGYRRQLRAAKVNIFRGHSSMSLQDAQEPATRVPNTNKHSVQGSNPIWLKGYDNEWFKSEESGSIGGHDSLDDNFLAVATQDMHETLKGTAKLFNNSNDLNRHFNLYNQIDKMTNNAQILARKLETTEL", "length": 1981 }, "evidence": [ { "id": "RGD:620420", "url": "https://alliancegenome.org/gene/RGD:620420#orthology", "database": "AGR" }, { "id": "RGD:619760", "url": "https://alliancegenome.org/gene/RGD:619760#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VGG5-1", "protein_name": "Cadherin-87A", "gene_name": "Cad87A", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKLPLGLLMICLGLTLAKGETNLPPVFTQTLNNIILYENVTVGTVVFRLEAYDPEGSPVTYGAIGADHFSVDPVSGNITLIKPLDREEKDTLKFLVSIRDRVDPEGESERDNVVEVPITFIILDLNDNPPEFQNTPYEADVNEDAAVGTTIFDKITVKDRDIVGESLDLKCLPQQQSPEACRKFRLHIIKRDATILEAAVVLNDTLNYNQRMVYHFQIEATDGPHKTQTTFEARVKDVQDKPPVFQGSLSTVIDEDSPINTLVLTVHARDGDTGEPRKIVYDLRTNPNDYFLLDAQTGELRTAKPLDREALEDSTGIISLVIRARELVNGVPSDDPLTSATAKATVTIRDVNDSPPVFNHKEYSVSLLENTLPGTPLALDMSVSDADVGINSKFALRLDDVSGVFDVEPKLVTGYSQVNIRVANGTLDYENPNQRKFIVLVVAEETDTNPRLSSTATITVSVLDANDNKPVFEQESYSASVSEAALPGQYIATITARDVDSGSYGDSGIRYSLSGTGAELFHVNEQTGVISLANCHDNGESNRRERRDLNEDEHVEEDDGEGHLEMLSMEAATREIGTEPTVQYTLITQAPEEQASSVPLPAPVPHAAPSGVPAATANDDKAPQTCLDYESETTYFLSYKATDDNGRGSASVVSLRISVTDANDSPPVCESPLYRASVDEGAVVFDSPLIVKARDADTMSRISYRIRGSEQVESIFDIDRETGQIIIRPNATLDVTNLNSDQLIFAVEANDGLFTAHCGVNITVRDVNNHVPNFEQQSYSAVVEENSEIGTSVERVHATDLDTGKNAELRYRIQQGSFDDFGIVETTGEVFVSRKLDFDRRNTYQLQIQASDQGTPSLTGTATLTINVQNSNDKDPYFVPATQHAEVRADAPPGQLVYTLIALDPDVANHNALEFAGTDDITAIDKEGKELPHYDQFKEYFKISRNGKVSVNKQLDRNLFAVMRINVLVTDSTAPNVQQGRGLLIIQIIDVNKNPPRFNAPWSVEQPQIKLQMVEEQPVGTVLTTLQANDEDSSIGEFNISDNDYFAINQTSGMIYTIARLDYEVVKEVKFQVTVSDTGVPALTATADVVVDIINLNDNDPKFSQSDYYFNVTENSPRGTVAGKVEAHDGDVGVFGEITYTLIGENNKYFSIDAYTGNVMVANSSILDREQIKELTLSVVAQDKAPAAVQKSATATIHINILDVNDNAPVFTRDVYNSTVAENAAYQPPAALLQVQAIDQDEGLYGDVRYIITAGNEMGLFKLDAQSGIVYPAQSLSGKHGAYELTISARDTQGSGTMESTTKAIITVLRVNRHKPEFVIPALSNATIEIPGDIVQPDYLLLTVRAMDNDTEENGKVSYHLQVNNRNEQQTGEFKIDEVTGELRAKTQLNRKNRANYDIILVARDAGNPPFESLRLLSVSIVDANENRPEFPDASNPYKVSINENSGRDVKIGHIQAASRSKHNRDIFYYMLLGNEDGAFYVDKLTGDIYTNKSLDREETDVYTLYILASIKADLHISEEERASFSIKTLNRDNTVAKVAITVLDVNDNPPVFEKPIYYAGVNANAKMGAAITLVNATDADQGKNAKIEFMIVASNLYKFGATKSTGSIVPSPFAISQDGRISANTIMAEYNQDRFELEIVARELEQPQSSASTKVNIWVFDGTQLVRVILSRPPEEVYQEQEEIIAELRNATQHRIIVDEIRFHLDSIGRIRMDWCDLYFHAVDPQTQQIAPVDEILKDIDRNYDYLKDYYAGFAIENVVPAYIAIVQDEFDLAVAGLVALVIVLFVGVISFIVLCCCLKHWNLSVPVETRRKEALIKKQIIEDLNTTENPLWIEQKLKLYEEQELTMQVFSEPDHISNSEAPGHLDHRSSLEQVHHVGQTVDNTYATIQPRNNQNRLTGGGGAGGGSMRSGGGASAGGVGGAGLLLARVDPHMNEFADYATLRNNRAPSLYEFTGSTFQAPIRDGDDAVAELI", "length": 1975 }, "evidence": [ { "id": "MGI:2687323", "url": "https://alliancegenome.org/gene/MGI:2687323#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VGW1-1", "protein_name": "Cadherin-86C", "gene_name": "Cad86C", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MASTSSSQPEKNRSHVPLCRLGTEPVSRTGAAEEPSGQRECYYYAPATSPHQHHHHHHQHHHHHRLKQHHRHHHHHHRLQHHHHHHQQQHNHQNQQMQHHWPSRLGPIGPWLGAMTAYRLLTISLLIGILCPHHVQGADPKFDPTTRMRLVLVPADAQVNSVIYRLRATDEEFDYPLTFEFVGDASASTVKVESLPCTKYNSVCQANIVLQRRLEPGRYYDFQVSVKDTKGGMTTQLCSITATNFTTPHDLIFPHKPGIIMIPEDAKRGTELDYVIARKNPLFQKPVYLELWGSPLFAIRQKIVSSETTEGTVFLLGPLDFEKQAMYHLTILANDAYAEPGQDSRNIAGMEIVVIVQDVQDQPPVFTSAPPVTKLPPGILPGDKILQVHAEDGDKGNPREVRYGLVSENNPFTSFFDINETSGEIFLMRPLEDIAFITHVGDPVLLTVIAEEVKVGRDEPPALASTVQLAFFLPDRTNSPPYFENDHYVSRVDENAPHGTALTFVDPYVPRVYDDDTGKNGVFSLTLLNNNGTFEISPNVAERSAGFLIRVRDNSMLDYEQQQSVQFQILAQELGPATNLSALVNVTVYINDVNDNAPVFEQPAYSVELPENMTAGTKVVQVLATDPDSGLGGKVRYTAILGYLNTSLNLDAETGLITVSTNKHGFDREVMPEYHLYVEARDMDGEGNRAQVPLIIKLIDVNDETPIFDKDLYEFILTHDLMGFTTTAVIHAEDKDATAPNNEVRYEIINGNYDNQFVLDKVTGELTVREKIHLRSKKNAKTRRRRQAGSDDEDTDIFILTARAYDLGVPVRFSTTTIRVYPPESRKRSVKFVVPGHNPDKAKTEETLSALSGGKVYIHNIRPLSPDEPGAKDIPAGNPGIKERSVVTATVIYDSSSVVDISEIQQRLSHHNNSYAIMPQDTSSTDTQYKAENKVLFWLLILLATLVALTILILLLCCICSWCPLYGAATKRIVNISRTEDDVHLVHREMANGKQTKSVQVAEWMGRRDAWSAEKPPDTRTKPTRWEFHDGREQLDEDVGRGQDIGEGDRRHIQSAEEQQRRVRIKHNRTAKDDLHLNFHNSRTNLINDRDVYMEDVIENRDLAGDREHITRTRVNRQEYARRKQYDSEVRHIDDDSMRRHEIDRGSDIDFNTAHNSLKSKRELFIKDGNVEILQLMTRDKTRDGLNLDDDNIYVNVPLKPAGNLSHPQLLMVDNTGKEILMRRFIEEQPDGKQIIREHYQIVPGATYIQSMPNEVQQGSTLKGDTFPLGKSGPNSIVYSQLEPEVKVIHTQPVQAGEGVSLDQQMQPAVSNQSLTHELEHSLKQQNALLRQILMEKEKLENAYTQHEVALETQSLPGQSMAIGTQTDCDAGTQTEGFDGVLDPEISLAKPSRRRARSENDESMSEDGYEYVRFNPPNSPEGVYWIKRRRTKKRPRQPRKRIVMVEEVKRKIRTPIKEEEEVQERKKRVPPKKPLRETKTSILRKQLSDESRKDQSRNGESQTGNRHRSESDSHNRDMFMEITDSMDELASPGSHSIRKIQVEKYYKHSDGDFDEDDTEYSIDSDGDEIVIRTNYPSRAQENERYRRQERTYAEPENPVDRKRPARKSSPTDSQPEAMPRLSRRDSSKRGSRKQTSSEPPHNRVSISKYESTVTENGRKLMSTSTEIVGSKRSLTDRSYQSETELAGLEHEERNVPKYMEWYYNKKKSSVSGRTSTESSKSQPSSKKKVGAAEKRVSKTRITAQPKDVEEYDETGGRYKPEPAPRKSPPKGSRLLKEDRALNKQHKPKIETDTNHPLLQHSEHRFERENALEVPAAPTKLPHYMYPETPPHAAAGGKESKSGRESKTSKEAKPKPSPIRENEVKVSNSKIYVEHRGTGHPTQKQLNASTLEDDHDSGIAMNSLLNSLGRRNPIAEKKSVFSIAYDDVSRVKKINSGGESPQYS", "length": 1943 }, "evidence": [ { "id": "HGNC:14550", "url": "https://alliancegenome.org/gene/HGNC:14550#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VVG0", "url": "https://www.uniprot.org/uniprotkb/Q9VVG0" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "Q9VVG0", "url": "https://www.uniprot.org/uniprotkb/Q9VVG0" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "Q9VVG0", "url": "https://www.uniprot.org/uniprotkb/Q9VVG0" } ], "pmid": "" }, { "name": "microvillus", "id": "GO:0005902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005902", "evidence": [ { "database": "UniProtKB", "id": "Q9VVG0", "url": "https://www.uniprot.org/uniprotkb/Q9VVG0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 10, "go_terms": [ { "name": "axonogenesis", "id": "GO:0007409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007409", "evidence": [ { "database": "UniProtKB", "id": "Q9VVG0", "url": "https://www.uniprot.org/uniprotkb/Q9VVG0" } ], "pmid": "" }, { "name": "epithelial cell differentiation", "id": "GO:0030855", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030855", "evidence": [ { "database": "UniProtKB", "id": "Q9VVG0", "url": "https://www.uniprot.org/uniprotkb/Q9VVG0" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "Q9VVG0", "url": "https://www.uniprot.org/uniprotkb/Q9VVG0" } ], "pmid": "" }, { "name": "developmental growth", "id": "GO:0048589", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048589", "evidence": [ { "database": "UniProtKB", "id": "Q9VVG0", "url": "https://www.uniprot.org/uniprotkb/Q9VVG0" } ], "pmid": "" }, { "name": "calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules", "id": "GO:0016339", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016339", "evidence": [ { "database": "UniProtKB", "id": "Q9VVG0", "url": "https://www.uniprot.org/uniprotkb/Q9VVG0" } ], "pmid": "" }, { "name": "establishment or maintenance of cell polarity", "id": "GO:0007163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007163", "evidence": [ { "database": "UniProtKB", "id": "Q9VVG0", "url": "https://www.uniprot.org/uniprotkb/Q9VVG0" } ], "pmid": "" }, { "name": "animal organ development", "id": "GO:0048513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048513", "evidence": [ { "database": "UniProtKB", "id": "Q9VVG0", "url": "https://www.uniprot.org/uniprotkb/Q9VVG0" } ], "pmid": "" }, { "name": "cell-cell adhesion mediated by cadherin", "id": "GO:0044331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044331", "evidence": [ { "database": "UniProtKB", "id": "Q9VVG0", "url": "https://www.uniprot.org/uniprotkb/Q9VVG0" } ], "pmid": "" }, { "name": "establishment of planar polarity", "id": "GO:0001736", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001736", "evidence": [ { "database": "UniProtKB", "id": "Q9VVG0", "url": "https://www.uniprot.org/uniprotkb/Q9VVG0" } ], "pmid": "" }, { "name": "dorsal appendage formation", "id": "GO:0046843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046843", "evidence": [ { "database": "UniProtKB", "id": "Q9VVG0", "url": "https://www.uniprot.org/uniprotkb/Q9VVG0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "Q9VVG0", "url": "https://www.uniprot.org/uniprotkb/Q9VVG0" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "Q9VVG0", "url": "https://www.uniprot.org/uniprotkb/Q9VVG0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1040, "end_pos": 1042, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1111, "end_pos": 1113, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1112, "end_pos": 1114, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1233, "end_pos": 1235, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1294, "end_pos": 1296, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1419, "end_pos": 1421, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1452, "end_pos": 1454, "annotation": 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{ "evidence": [ { "id": "Q9VVG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVG0" }, { "id": "PS50268", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50268" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cadherin", "eco_id": "ECO_0000259", "start_pos": 28, "end_pos": 128, "start_aa": "Thr", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1523 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1040, "end_pos": 1042 }, { "start_pos": 1111, "end_pos": 1113 }, { "start_pos": 1112, "end_pos": 1114 }, { "start_pos": 1233, "end_pos": 1235 }, { "start_pos": 1294, "end_pos": 1296 }, { "start_pos": 1419, "end_pos": 1421 }, { "start_pos": 1452, "end_pos": 1454 }, { "start_pos": 1557, "end_pos": 1559 }, { "start_pos": 1584, "end_pos": 1586 }, { "start_pos": 1610, "end_pos": 1612 }, { "start_pos": 191, "end_pos": 193 }, { "start_pos": 371, "end_pos": 373 }, { "start_pos": 435, "end_pos": 437 }, { "start_pos": 678, "end_pos": 680 }, { "start_pos": 727, "end_pos": 729 }, { "start_pos": 868, "end_pos": 870 }, { "start_pos": 890, "end_pos": 892 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", 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] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VVH0-1", "uniprot_ac": "Q9VVH0", "uniprot_id": "Q9VVH0_DROME", "mass": { "chemical_mass": 65508.0, "monoisotopic_mass": 65508.0 }, "refseq": { "ac": "NP_648980", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648980" }, "gene_names": [ { "name": "Pykl4", "type": "recommended", "evidence": [ { "id": "Q9VVH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVH0" } ] }, { "name": "CG12229", "type": "synonym", "evidence": [ { "id": "NP_648980", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648980" }, { "id": "Q9VVH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVH0" } ] }, { "name": "Dmel\\CG12229", "type": "synonym", "evidence": [ { "id": "NP_648980", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648980" }, { "id": "Q9VVH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVH0" } ] }, { "name": "Dmel_CG12229", "type": "synonym", "evidence": [ { "id": "Q9VVH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVH0" } ] } ], "protein_names": [ { "name": "Pyruvate kinase C-terminal domain-containing protein", "type": "recommended", "evidence": [ { "id": "Q9VVH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVH0/entry#names_and_taxonomy" } ] }, { "name": "CG12229-PA", "type": "synonym", "evidence": [ { "id": "NP_648980", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648980" } ] }, { "name": "pyruvate kinase", "type": "synonym", "evidence": [ { "id": "NP_648980", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648980" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_648980", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648980" } ] } ], "function": [], "disease": [], 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"database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_648980", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648980", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VVH0", "url": "https://www.uniprot.org/uniprotkb/Q9VVH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VVH0-1", "url": "https://www.uniprot.org/uniprotkb/Q9VVH0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPINQKEVTPQLDSQTGEDQGEEEEQPEDENRLEKFTVRLNGQHDLEQRLKDFKAACEAHEKHARRRKRKRYYHLGLVAKLVTETTHDELRRMLENGTYTFHVDTVGNKPDELKAILDTMNIAISAHSAERELRLTTGLALEINGECCRVGRLRNNCTVMLARGGVVTLTTDESYRYKGFKEIVYVINLRCYLASVQLGDIVMIGREVRGKVVKTLREALTVMIIDAGLVASYDFIELPRQCHALDPDLYPDLYMKDLEMAASLNANYVVLPKIRCKSFLRAVRQTLNSDFNLKLIGMIDFEYVRSNMLDLLGIIKLVDYIWIPDMFNVNCCVYNYIMEDVLPISQCQKKPVIGTVPLERCSDFKRFELHDFLWKVDAIHIQKSPWCNKYPLIVKKLMPIKDYRVGAVQNKMVLKSILTSYQTIVNFIIRTISSIECQAIFLFTTCETASVALSRIEIYCPVYVMVPLEETDDAETITCKVELARALHLRRNMHPVLYTKDLNECSYSPIEFGVDFMRKKGCLEVGDFVVTLEVGKEDKDNVVIGIGEDVCILRAFYVSPLFACEKFKYGG", "length": 571, "header": "tr|Q9VVH0-1|Q9VVH0_DROME Isoform 1 of Pyruvate kinase C-terminal domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Pykl4 PE=4 SV=1 CANONICAL=Q9VVH0-1" }, "isoforms": [ { "isoform_ac": "Q9VVH0-1", "url": "https://www.uniprot.org/uniprotkb/Q9VVH0/entry#Q9VVH0-1", "sequence": { "sequence": "MPINQKEVTPQLDSQTGEDQGEEEEQPEDENRLEKFTVRLNGQHDLEQRLKDFKAACEAHEKHARRRKRKRYYHLGLVAKLVTETTHDELRRMLENGTYTFHVDTVGNKPDELKAILDTMNIAISAHSAERELRLTTGLALEINGECCRVGRLRNNCTVMLARGGVVTLTTDESYRYKGFKEIVYVINLRCYLASVQLGDIVMIGREVRGKVVKTLREALTVMIIDAGLVASYDFIELPRQCHALDPDLYPDLYMKDLEMAASLNANYVVLPKIRCKSFLRAVRQTLNSDFNLKLIGMIDFEYVRSNMLDLLGIIKLVDYIWIPDMFNVNCCVYNYIMEDVLPISQCQKKPVIGTVPLERCSDFKRFELHDFLWKVDAIHIQKSPWCNKYPLIVKKLMPIKDYRVGAVQNKMVLKSILTSYQTIVNFIIRTISSIECQAIFLFTTCETASVALSRIEIYCPVYVMVPLEETDDAETITCKVELARALHLRRNMHPVLYTKDLNECSYSPIEFGVDFMRKKGCLEVGDFVVTLEVGKEDKDNVVIGIGEDVCILRAFYVSPLFACEKFKYGG", "length": 571, "header": "tr|Q9VVH0-1|Q9VVH0_DROME Isoform 1 of Pyruvate kinase C-terminal domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Pykl4 PE=4 SV=1 CANONICAL=Q9VVH0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VVH0", "url": "https://www.uniprot.org/uniprotkb/Q9VVH0" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VVH0", "url": "https://www.uniprot.org/uniprotkb/Q9VVH0" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVH0", "url": "https://www.uniprot.org/uniprotkb/Q9VVH0" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVH0", "url": "https://www.uniprot.org/uniprotkb/Q9VVH0" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VVH0", "url": "https://www.uniprot.org/uniprotkb/Q9VVH0" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VVH0", "url": "https://www.uniprot.org/uniprotkb/Q9VVH0" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VVH0", "url": "https://www.uniprot.org/uniprotkb/Q9VVH0" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVH0", "url": "https://www.uniprot.org/uniprotkb/Q9VVH0" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVH0", "url": "https://www.uniprot.org/uniprotkb/Q9VVH0" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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Disease onset is usually in early to mid-adulthood. Sudden cardiac death may occur and may be the presenting symptom. In some cases, it is associated with skeletal myopathy and elevated serum creatine kinase." }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "CDCD1", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "LMNA familial isolated dilated cardiomyopathy", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "cardiomyopathy dilated with conduction defect type 1", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "cardiomyopathy, dilated, type 1A", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "dilated cardiomyopathy 1A", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "dilated cardiomyopathy type 1A", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "familial dilated cardiomyopathy with conduction defect due to LMNA mutation", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "familial isolated dilated cardiomyopathy caused by mutation in LMNA", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "cardiomyopathy, dilated, 1A", "description": "" }, { "id": "MIM:115200", "resource": "MIM", "url": "https://www.omim.org/entry/115200", "name": "Cardiomyopathy, dilated, 1A", "description": "Cardiomyopathy, dilated, 1A" } ], "unlinked_id_list": [], "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ] }, { "disease_id": "DOID:14115", "recommended_name": { "id": "DOID:14115", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14115", "name": "toxic shock syndrome", "description": "A commensal bacterial infectious disease that results_in infection, has_material_basis_in Streptococcus pyogenes or has_material_basis_in Staphylococcus aureus, which produce toxins that are absorbed systemically and produce the systemic manifestations. The infection has_symptom fever, has_symptom rash, has_symptom hypotension, has_symptom multiorgan failure, has_symptom desquamation, has_symptom vomiting, has_symptom diarrhea, has_symptom headache, and has_symptom nonfocal neurologic abnormalities." }, "synonyms": [ { "id": "DOID:14115", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14115", "name": "TSS", "description": "" }, { "id": "DOID:14115", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14115", "name": "toxic shock", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "14115", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14115" } ] }, { "disease_id": "DOID:1588", "recommended_name": { "id": "DOID:1588", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1588", "name": "thrombocytopenia", "description": "A blood platelet disease that is characterized by low a platelet count in the blood." }, "synonyms": [ { "id": "MONDO:0008555", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008555", "name": "thrombocytopenia 2", "description": "An autosomal dominant disorder caused by mutation(s) in the ANKRD26 gene, encoding ANKRD26 protein. Additionally, in one family, a mutation(s) has been identified in the MASTL gene, encoding serine/threonine-protein kinase greatwall. The condition is characterized by mild to moderate bruisability." }, { "id": "MONDO:0008555", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008555", "name": "thrombocytopenia 2", "description": "" }, { "id": "MONDO:0008555", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008555", "name": "thrombocytopenia type 2", "description": "" }, { "id": "MONDO:0008555", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008555", "name": "THC2", "description": "" }, { "id": "MONDO:0008555", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008555", "name": "thrombocytopenia autosomal dominant 2", "description": "" }, { "id": "MONDO:0010120", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010120", "name": "thrombocytopenia 3", "description": "" }, { "id": "MONDO:0010120", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010120", "name": "THC3", "description": "" }, { "id": "MONDO:0010120", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010120", "name": "thrombocytopenia 3", "description": "" }, { "id": "MONDO:0010308", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010308", "name": "thrombocytopenia, X-linked, with or without dyserythropoietic anemia", "description": "An X-linked condition caused by mutation(s) in the GATA1 gene, encoding erythroid transcription factor. It is characterized by thrombocytopenia, as well as abnormal platelet function and morphology. Dyserythropoietic anemia of variable severity may also be present." }, { "id": "MONDO:0010308", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010308", "name": "X-linked thrombocytopenia, with or without dyserythropoietic Anaemia", "description": "" }, { "id": "MONDO:0010308", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010308", "name": "X-linked thrombocytopenia, with or without dyserythropoietic Anemia", "description": "" }, { "id": "MONDO:0010308", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010308", "name": "thrombocytopenia, X-linked, with or without dyserythropoietic anemia", "description": "" }, { "id": "MONDO:0010308", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010308", "name": "thrombocytopenia, X-linked, with or without dyserythropoietic anemia, X-linked recessive", "description": "" }, { "id": "MONDO:0010308", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010308", "name": "XLTDA", "description": "" }, { "id": "MONDO:0010743", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010743", "name": "thrombocytopenia 1", "description": "" }, { "id": "MONDO:0010743", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010743", "name": "X-linked thrombocytopenia with normal platelets", "description": "" }, { "id": "MONDO:0010743", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010743", "name": "thrombocytopenia 1", "description": "" }, { "id": "MONDO:0010743", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010743", "name": "thrombocytopenia type 1", "description": "" }, { "id": "MONDO:0010743", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010743", "name": "thrombocytopenia, X-linked, X-linked recessive", "description": "" }, { "id": "MONDO:0010743", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010743", "name": "thrombocytopenia, X-linked, intermittent, X-linked recessive", "description": "" }, { "id": "MONDO:0010743", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010743", "name": "THC", "description": "" }, { "id": "MONDO:0010743", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010743", "name": "THC1", "description": "" }, { "id": "MONDO:0010743", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010743", "name": "X-linked thrombocytopenia", "description": "" }, { "id": "MONDO:0010743", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010743", "name": "XLT", "description": "" }, { "id": "MONDO:0012775", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012775", "name": "thrombocytopenia 4", "description": "Any thrombocytopenia in which the cause of the disease is a mutation in the CYCS gene." }, { "id": "MONDO:0012775", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012775", "name": "CYCS thrombocytopenia", "description": "" }, { "id": "MONDO:0012775", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012775", "name": "thrombocytopenia 4", "description": "" }, { "id": "MONDO:0012775", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012775", "name": "thrombocytopenia caused by mutation in CYCS", "description": "" }, { "id": "MONDO:0012775", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012775", "name": "thrombocytopenia type 4", "description": "" }, { "id": "MONDO:0012775", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012775", "name": "THC4", "description": "" }, { "id": "MIM:188000", "resource": "MIM", "url": "https://www.omim.org/entry/188000", "name": "Thrombocytopenia 2", "description": "Thrombocytopenia 2" }, { "id": "MIM:273900", "resource": "MIM", "url": "https://www.omim.org/entry/273900", "name": "Thrombocytopenia 3", "description": "Thrombocytopenia 3" }, { "id": "MIM:300367", "resource": "MIM", "url": "https://www.omim.org/entry/300367", "name": "X-linked dyserythropoietic anemia and thrombocytopenia", "description": "X-linked dyserythropoietic anemia and thrombocytopenia" }, { "id": "MIM:313900", "resource": "MIM", "url": "https://www.omim.org/entry/313900", "name": "Thrombocytopenia 1", "description": "Thrombocytopenia 1" }, { "id": "MIM:612004", "resource": "MIM", "url": "https://www.omim.org/entry/612004", "name": "Thrombocytopenia 4", "description": "Thrombocytopenia 4" } ], "unlinked_id_list": [], "evidence": [ { "id": "1588", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1588" } ] }, { "disease_id": "DOID:1591", "recommended_name": { "id": "DOID:1591", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1591", "name": "renovascular hypertension", "description": "" }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "1591", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1591" } ] }, { "disease_id": "DOID:1679", "recommended_name": { "id": "DOID:1679", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1679", "name": "cystitis", "description": "A bladder disease that is characterized by inflammation of the bladder." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "1679", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1679" } ] }, { "disease_id": "DOID:219", "recommended_name": { "id": "DOID:219", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:219", "name": "colon cancer", "description": "A colorectal cancer that is located_in the colon." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:219" } ] }, { "disease_id": "DOID:2218", "recommended_name": { "id": "DOID:2218", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2218", "name": "blood platelet disease", "description": "A blood coagulation disease that is characterized by an abnormal increase or decrease in platelets or platelet dysfunction." }, "synonyms": [ { "id": "DOID:2218", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2218", "name": "Thrombocytopathy", "description": "" }, { "id": "DOID:2218", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2218", "name": "platelet disorder", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "2218", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2218" } ] }, { "disease_id": "DOID:224", "recommended_name": { "id": "DOID:224", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:224", "name": "transient cerebral ischemia", "description": "A brain ischemia that is characterized by ischemia of brief duration and without resultant tissue death." }, "synonyms": [ { "id": "DOID:224", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:224", "name": "TIA", "description": "" }, { "id": "DOID:224", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:224", "name": "TIA - Transient ischaemic attack", "description": "" }, { "id": "DOID:224", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:224", "name": "Transient cerebral ischaemia", "description": "" }, { "id": "DOID:224", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:224", "name": "Transient ischemic attacks", "description": "" }, { "id": "DOID:224", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:224", "name": "transient ischemic attack", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:224" } ] }, { "disease_id": "DOID:2349", "recommended_name": { "id": "DOID:2349", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2349", "name": "arteriosclerosis", "description": "An artery disease that is characterized by a thickening and hardening of arterial walls in the arteries." }, "synonyms": [ { "id": "DOID:2349", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2349", "name": "Arteriosclerotic vascular disease", "description": "" } ], "unlinked_id_list": [ "DOID:2348" ], "evidence": [ { "id": "2349", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2349" } ] }, { "disease_id": "DOID:2841", "recommended_name": { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing." }, "synonyms": [ { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "bronchial hyperreactivity", "description": "" }, { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "chronic obstructive asthma", "description": "" }, { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "chronic obstructive asthma with acute exacerbation", "description": "" }, { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "chronic obstructive asthma with status asthmaticus", "description": "" }, { "id": "MONDO:0010940", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010940", "name": "inherited susceptibility to asthma", "description": "" }, { "id": "MONDO:0010940", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010940", "name": "asthma, nocturnal, susceptibility to", "description": "" }, { "id": "MIM:600807", "resource": "MIM", "url": "https://www.omim.org/entry/600807", "name": "Asthma", "description": "Asthma" } ], "unlinked_id_list": [ "DOID:0080811", "DOID:0080819" ], "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ] }, { "disease_id": "DOID:2876", "recommended_name": { "id": "DOID:2876", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2876", "name": "laryngeal squamous cell carcinoma", "description": "A laryngeal carcinoma that has_material_basis_in squamous cells." }, "synonyms": [ { "id": "DOID:2876", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2876", "name": "Epidermoid carcinoma of the Larynx", "description": "" }, { "id": "DOID:2876", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2876", "name": "squamous cell carcinoma of larynx", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "2876", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2876" } ] }, { "disease_id": "DOID:3021", "recommended_name": { "id": "DOID:3021", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3021", "name": "acute kidney failure", "description": "" }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "3021", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3021" } ] }, { "disease_id": "DOID:3083", "recommended_name": { "id": "DOID:3083", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3083", "name": "chronic obstructive pulmonary disease", "description": "An obstructive lung disease that is a chronic and progressive disorder of small airways in the lungs and that is characterized by irreversible airflow obstruction, typically identified by reductions in quantitative spirometric indices, induced forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (less than 0.7 is diagnostic of COPD). Lung volume is increased and pulmonary hypertension may occur. The pathologic changes result in the disruption of the airflow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough and chest tightness. COPD is a consequence (an end result) of chronic bronchitis, emphysema or both." }, "synonyms": [ { "id": "DOID:3083", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3083", "name": "COLD", "description": "" }, { "id": "DOID:3083", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3083", "name": "COPD", "description": "" }, { "id": "DOID:3083", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3083", "name": "chronic obstructive airway disease", "description": "" }, { "id": "DOID:3083", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3083", "name": "chronic obstructive lung disease", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "chronic obstructive pulmonary disease", "description": "A chronic and progressive lung disorder characterized by the loss of elasticity of the bronchial tree and the air sacs, destruction of the air sacs wall, thickening of the bronchial wall, and mucous accumulation in the bronchial tree. The pathologic changes result in the disruption of the air flow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough, and chest tightness. The two main types of chronic obstructive pulmonary disease are chronic obstructive bronchitis and emphysema." }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "COLD", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "COPD", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "COPD, chronic obstructive pulmonary disease", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "chronic obstructive airways disease", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "chronic obstructive lung disease", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "chronic obstructive pulmonary disease (COPD)", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "chronic obstructive pulmonary disease, (COPD)", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "cold", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "cold (chronic obstructive lung disease)", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "disease (COPD), chronic obstructive", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "obstructive lung disease, chronic", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "obstructive pulmonary disease (COPD), chronic", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "pulmonary disease (COPD), chronic obstructive", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "3083", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3083" } ] }, { "disease_id": "DOID:3627", "recommended_name": { "id": "DOID:3627", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3627", "name": "aortic aneurysm", "description": "An aortic disease that is characterized by an enlargement (dilation) of the aorta to greater than 1.5 times normal size." }, "synonyms": [ { "id": "DOID:3627", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3627", "name": "ruptured aortic aneurysm", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "3627", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3627" } ] }, { "disease_id": "DOID:3907", "recommended_name": { "id": "DOID:3907", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3907", "name": "lung squamous cell carcinoma", "description": "A non-small cell lung carcinoma that has_material_basis_in the squamous cell." }, "synonyms": [ { "id": "DOID:3907", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3907", "name": "Epidermoid cell carcinoma of the lung", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "3907", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3907" } ] }, { "disease_id": "DOID:6432", "recommended_name": { "id": "DOID:6432", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:6432", "name": "pulmonary hypertension", "description": "A hypertension characterized by an increase of blood pressure in the pulmonary artery, pulmonary vein or pulmonary capillaries." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "6432", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6432" } ] }, { "disease_id": "DOID:7147", "recommended_name": { "id": "DOID:7147", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:7147", "name": "ankylosing spondylitis", "description": "An arthritis that results_in inflammation in the joints of the spine and pelvis. The disease has_symptom pain, has_symptom stiffness in the spine, has_symptom stiffness in the neck, has_symptom stiffness in the hips, has_symptom stiffness in the jaw and has_symptom stiffness in the rib cage." }, "synonyms": [ { "id": "DOID:7147", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:7147", "name": "Bekhterev syndrome", "description": "" }, { "id": "DOID:7147", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:7147", "name": "Bekhterev's disease", "description": "" }, { "id": "DOID:7147", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:7147", "name": "Marie-Strumpell disease", "description": "" }, { "id": "MONDO:0007126", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007126", "name": "spondyloarthropathy, susceptibility to, 1", "description": "Any spondyloarthropathy, susceptibility to in which the cause of the disease is a mutation in the HLA-B gene." }, { "id": "MONDO:0007126", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007126", "name": "HLA-B spondyloarthropathy, susceptibility to", "description": "" }, { "id": "MONDO:0007126", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007126", "name": "spondyloarthropathy, susceptibility to caused by mutation in HLA-B", "description": "" }, { "id": "MONDO:0007126", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007126", "name": "spondyloarthropathy, susceptibility to, 1", "description": "" }, { "id": "MONDO:0007126", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007126", "name": "spondyloarthropathy, susceptibility to, type 1", "description": "" }, { "id": "MONDO:0007126", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007126", "name": "SPDA1", "description": "" }, { "id": "MIM:106300", "resource": "MIM", "url": "https://www.omim.org/entry/106300", "name": "Spondyloarthropathy 1", "description": "Spondyloarthropathy 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "7147", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7147" } ] }, { "disease_id": "DOID:783", "recommended_name": { "id": "DOID:783", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:783", "name": "end stage renal disease", "description": "A chronic kidney disease is characterized by non-functioning kidneys, as the final stage in chronic kidney disease." }, "synonyms": [ { "id": "DOID:783", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:783", "name": "end stage renal failure", "description": "" }, { "id": "DOID:783", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:783", "name": "end-stage kidney disease", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "783", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:783" } ] }, { "disease_id": "DOID:820", "recommended_name": { "id": "DOID:820", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:820", "name": "myocarditis", "description": "An extrinsic cardiomyopathy that is characterized as an inflammation of the heart muscle." }, "synonyms": [ { "id": "DOID:820", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:820", "name": "Myocardial inflammation", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "820", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:820" } ] }, { "disease_id": "DOID:8577", "recommended_name": { "id": "DOID:8577", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8577", "name": "ulcerative colitis", "description": "A colitis that is predominantly confined to the mucosa located_in colon and includes characteristic ulcers, or open sores." }, "synonyms": [ { "id": "DOID:8577", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8577", "name": "Left-sided ulcerative colitis", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "8577", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8577" } ] }, { "disease_id": "DOID:9415", "recommended_name": { "id": "DOID:9415", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9415", "name": "allergic asthma", "description": "An extrinsic asthma that is characterized by symptoms that are triggered by an allergic reaction caused by inhaled allergens such as dust mite allergen, pet dander, pollen and mold. The disease has_symptom coughing, has_symptom wheezing, has_symptom shortness of breath or has_symptom rapid breathing, and has_symptom chest tightness." }, "synonyms": [ { "id": "DOID:9415", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9415", "name": "extrinsic asthma with acute exacerbation", "description": "" }, { "id": "DOID:9415", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9415", "name": "extrinsic asthma with status asthmaticus", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "9415", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9415" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VVJ1", "url": "https://www.uniprot.org/uniprotkb/Q9VVJ1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Pgr", "url": "https://www.uniprot.org/uniprotkb/Q9VVJ1", "locus": { "chromosome": "3L", "start_pos": 17638001, "end_pos": 17633449, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0036742", "url": "https://www.ensemblgenomes.org/id/FBgn0036742" } ] } } ], "crossref": [ { "id": "FB:FBgn0036742", "url": "https://alliancegenome.org/gene/FB:FBgn0036742", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0036742", "url": "https://bgee.org/?page=gene&gene_id=FBgn0036742", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0036742", "url": "https://flybase.org/reports/FBgn0036742", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "39966", "url": "https://www.ncbi.nlm.nih.gov/gene/39966", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008365", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008365", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG7497", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG7497", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VGHVVWR", "url": "https://omabrowser.org/oma/group/VGHVVWR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VVJ1", "url": "https://www.orthodb.org/?gene=Q9VVJ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11866", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11866", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11866:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11866:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-391908", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-391908", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-392851", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-392851", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-416482", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-416482", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-418594", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-418594", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-428930", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-428930", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001287100", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287100", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VVJ1", "url": "https://www.uniprot.org/uniprotkb/Q9VVJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VVJ1-1", "url": "https://www.uniprot.org/uniprotkb/Q9VVJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METTTPVLDLLMPHNSTTVAPPKALYANRNRLIIGVIIMVLGVFGNSLALFILARKKLNKNSKYTLMLRCLATNNLVALLGMLTTTLLKMYLSKEVLQSFIRVDCVGLVVWRFFGLSSGCIAAVMAAERWMALARPFIYHKHITYELIRKSINSILMIAVVITFLPFVGFGAYIDESNPDQLKCIRYRDAPGVWNKTYAVLFMVFGTLLCIVIVACNLFVAHTLLCVIGRSRTAKRHMHYDLVSRDKNSAISIDPESSSGTTLYQTQLSTGSGNSHRSVQPARQYRHSVSVTMAATDSSPVEIKFAKLMAFLSISFVICWMPQMIAIPLAIAPNRVPASNKFFIIADVLTALHFTSDPYVYVLSRSKSINWSLLGCIKRWRSGWRPGGLRRSQSDQSRMRTTMTEANTLEFN", "length": 412, "header": "tr|Q9VVJ1-1|Q9VVJ1_DROME Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Pgr PE=1 SV=3 CANONICAL=Q9VVJ1-1" }, "isoforms": [ { "isoform_ac": "Q9VVJ1-1", "url": "https://www.uniprot.org/uniprotkb/Q9VVJ1/entry#Q9VVJ1-1", "sequence": { "sequence": "METTTPVLDLLMPHNSTTVAPPKALYANRNRLIIGVIIMVLGVFGNSLALFILARKKLNKNSKYTLMLRCLATNNLVALLGMLTTTLLKMYLSKEVLQSFIRVDCVGLVVWRFFGLSSGCIAAVMAAERWMALARPFIYHKHITYELIRKSINSILMIAVVITFLPFVGFGAYIDESNPDQLKCIRYRDAPGVWNKTYAVLFMVFGTLLCIVIVACNLFVAHTLLCVIGRSRTAKRHMHYDLVSRDKNSAISIDPESSSGTTLYQTQLSTGSGNSHRSVQPARQYRHSVSVTMAATDSSPVEIKFAKLMAFLSISFVICWMPQMIAIPLAIAPNRVPASNKFFIIADVLTALHFTSDPYVYVLSRSKSINWSLLGCIKRWRSGWRPGGLRRSQSDQSRMRTTMTEANTLEFN", "length": 412, "header": "tr|Q9VVJ1-1|Q9VVJ1_DROME Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Pgr PE=1 SV=3 CANONICAL=Q9VVJ1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VVJ1", "url": "https://www.uniprot.org/uniprotkb/Q9VVJ1" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VVJ1", "url": "https://www.uniprot.org/uniprotkb/Q9VVJ1" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVJ1", "url": "https://www.uniprot.org/uniprotkb/Q9VVJ1" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVJ1", "url": "https://www.uniprot.org/uniprotkb/Q9VVJ1" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VVJ1", "url": "https://www.uniprot.org/uniprotkb/Q9VVJ1" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VVJ1", "url": "https://www.uniprot.org/uniprotkb/Q9VVJ1" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VVJ1", "url": "https://www.uniprot.org/uniprotkb/Q9VVJ1" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVJ1", "url": "https://www.uniprot.org/uniprotkb/Q9VVJ1" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVJ1", "url": "https://www.uniprot.org/uniprotkb/Q9VVJ1" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VVJ1", "url": "https://www.uniprot.org/uniprotkb/Q9VVJ1" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VVJ1", "url": "https://www.uniprot.org/uniprotkb/Q9VVJ1" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG7497", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG7497", "resource": "KEGG Pathway" }, { "id": "R-DME-391908", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-391908", "resource": "Reactome", "description": "Prostanoid ligand receptors" }, { "id": "R-DME-392851", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-392851", "resource": "Reactome", "description": "Prostacyclin signalling through prostacyclin receptor" }, { "id": "R-DME-416482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-416482", "resource": "Reactome", "description": "G alpha (12/13) signalling events" }, { "id": "R-DME-418594", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-418594", "resource": "Reactome", "description": "G alpha (i) signalling events" }, { "id": "R-DME-428930", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-428930", "resource": "Reactome", "description": "Thromboxane signalling through TP receptor" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1N8D3-1", "protein_name": "Prostaglandin E2 receptor EP4 subtype", "gene_name": "ptger4a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEPTVPTIPAIMFIFGVISNLIAIVVLCKSRREQKETTFYTLVCGLAVTDLLGTVLASPVTIATYVKGAWPDGDPLCQYFGFVLLFFSLAGLSIICAMSIERYIAINHAYFYNDYVDKRLAGVTLLAIYASNILFCALPSVGFGEVKMQYPQTWCFIDWRTNVSAHAAFSYMYAGCSSLLILVTVVCNVLVCGALIRMHRRFVRRTSLGTDPQRAADPGRSRSFSRLAGAEIQMVILLIATSAVVLICSIPLVVQVFLNQLYKTPVEKRLDKNPDLLAIRFASTNPILDPWIYILLRKAVLSKVVENIKCLFCRSDSRGQQTQNSLLCINGQQFSSRDSPSAVSRELQDVSSTSQTSLNLAKAPDGGQNSSSESCRCSSHDGQCKKQSLQMSITNDSVQEKSI", "length": 403 }, "evidence": [ { "id": "HGNC:9596", "url": "https://alliancegenome.org/gene/HGNC:9596#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060222-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060222-1#orthology", "database": "AGR" }, { "id": "MGI:104311", "url": "https://alliancegenome.org/gene/MGI:104311#orthology", "database": "AGR" }, { "id": "RGD:628641", "url": "https://alliancegenome.org/gene/RGD:628641#orthology", "database": "AGR" }, { "id": "FB:FBgn0036742", "url": "https://alliancegenome.org/gene/FB:FBgn0036742#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A3QK20-1", "protein_name": "Prostaglandin E2 receptor EP4 subtype", "gene_name": "ptger4b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKRTCGKYDRQVDWGSEYITSMNFHDMDLQLNATNNSVVKMSKTTLNGYPIPVIMFIVGVVGNVIAIVVLRKSRKEQKETTFYTLVCGLAVTDLLGTLLASPVTIATYVKGEWPGGMPLCQYSGFILLFFSLAGLSIICAMSVERYLAINHAYFYNHYVDQRVAGLTLGGIYVSNALFCALPSMGLGSVVIQHPGTWCFIDWHNKTDTTTATFSYMYASFSSVLILATVVCNVLVCAALIMMHKRFVRRTSLGTDQGRVAEIRRRRSFARLAAAEIQMVIVLIATSTVVLICSTPLVVQVFVNQLFNSAADSSARPNPDPDLKAIRIASVNPILDPWIYILLRKTVVQKILEKIKCLFCRIGGRSHRRNTSDFHCDNDLRTSSVVSRDLPSMGLPELPEVISTSQTYLYPLEAGQGMGCCGDSVPSRTCSTSTEQTLLQDSQVADFSSGENRTEKSTDFEESSLCEHSNTNEEQCSKHQPLQVTFTDETLSFQERTI", "length": 497 }, "evidence": [ { "id": "HGNC:9596", "url": "https://alliancegenome.org/gene/HGNC:9596#orthology", "database": "AGR" }, { "id": "MGI:104311", "url": "https://alliancegenome.org/gene/MGI:104311#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FD73-1", "protein_name": "Prostaglandin E2 receptor EP3 subtype", "gene_name": "ptger3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASKCKSSTVLLQNLTAGIMPDSNISKSSQDSPGRSAGCGSVSVFFPITMMVTGMVGNSLAMLLVYSAYRKKENKRKRSFLLCIGSLALTDLFGQLLTSPIVISVYRADMKWDRVDPSKTLCAFFGVCMTTFGLCPLFLASAMAIERALAIIAPHWYSHYMKTSVTKQVLVIIWCLVLLFALLPIAGVGEYTLQWPGTWCFINTGDKDVTGNTFFATTFAALGIFSLLVTLSCNVVTIRALVTRCKTKSSSTQSSKQWERLTTETVIQLMGIMCVLLTCWSPLLVLMLKMILTHTSSHHCYSAGSLSPQELQKDCNFFLTAIRLASLNQILDPWVYLLLREILLRKFCQVASAVSKCSLDVQKQTQCPLDVQNKKAIQNDDVHKQSLNVENSILNVGCEEQ", "length": 401 }, "evidence": [ { "id": "HGNC:9595", "url": "https://alliancegenome.org/gene/HGNC:9595#orthology", "database": "AGR" }, { "id": "MGI:97795", "url": "https://alliancegenome.org/gene/MGI:97795#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FE45-1", "protein_name": "Prostacyclin receptor", "gene_name": "ptgir", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLSNQSCENITSIEANGNPGTSTVMFIAGVVGNLIALAILGVHQKDRRTKSSVFCILVTGLALTDLLGTCLLSPPVFICYAYRTSLVGLTGDQRLCGLFAFAMTFFILASMLILCAMAVERCLAISHPYFYSKHVRRSFAKIVLLLIYLFTFVFCLMPFFGYGRHKQYCPGTWCFIKMEVEEGDDEERRSLAFSLSYAVLMALLIAIVFMCNGSVIVSLCRMHRSQLTRRGSVVSAGRKRRLSTWFGQGEEEMDHLLLLASMTLIFVICSLPLTICGFENAISPVGNDQRNLTAFRFSAFNPILDPWIFIIFRKAVFHHIRALFRCCFPREAVKTTAQSSQELKAEDIKHSSSIQSKIYHSLPQ", "length": 364 }, "evidence": [ { "id": "HGNC:9602", "url": "https://alliancegenome.org/gene/HGNC:9602#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120511-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120511-1#orthology", "database": "AGR" }, { "id": "MGI:99535", "url": "https://alliancegenome.org/gene/MGI:99535#orthology", "database": "AGR" }, { "id": "RGD:1310890", "url": "https://alliancegenome.org/gene/RGD:1310890#orthology", "database": "AGR" }, { "id": "FB:FBgn0036742", "url": "https://alliancegenome.org/gene/FB:FBgn0036742#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1MZJ8-1", "protein_name": "Prostaglandin E2 receptor EP4 subtype", "gene_name": "PTGER4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTAPGTNASSSQASNPLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCGLAVTDLLGTLLVSPVTIATYLKGQWPGGHALCEYSTFILLFFGLSGLSIICAMSIERYLAINHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPSMGLGSSRLQYPATWCFIDWTTNVTAHAAFSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLGTEQQHHAAAAAVALAPTACRAPPAASSPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLYRPQLEPVISKNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRIGGSRRERSGPHCSDSRRTSSAVSGHSRSFLSRELKEISSTSQTLLYTPELSENGLGGGRNLLPGVPGVGLTQIDSTSLRTLRISETSDSSQGQDSESFLLVDEVGGSCRAGPAPKGSSLQVTFPSETLNLSEKCI", "length": 492 }, "evidence": [ { "id": "Q9VVJ1", "url": "https://omabrowser.org/oma/group/Q9VVJ1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "I3LLK4-1", "protein_name": "Prostaglandin E2 receptor EP4 subtype", "gene_name": "PTGER4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATPGANASALASDRPNGPVTIPAVMFIFGVVGNLIAIVVLCKSRKEQKETTFYTLVCGLAVTDLLGTLLVSPVTIATYMKGHWPGGPALCEYSTFILLFFGLSGLSIICAMSIERYLAINHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFIDWTTNVTAHAAFSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAAVAVAPATCRGPPSAASPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLYQPSSERVISKNPDLQAIRIAAVNPILDPWIYILLQKTVLSKAIEKIKCLFCRIGGSRREHPGQHCSDSRRTSSAMSGHSRSFLSRELKEVSSTSQTLLYMPDLSENGLGGRNLLPGVPGMGLTQTDSTSLRTLRVSETSDSSQGQDSESVLLVDEVAGSCRAVPAPKGSTLQVPFPNETLNLTEKCI", "length": 489 }, "evidence": [ { "id": "Q9VVJ1", "url": "https://omabrowser.org/oma/group/Q9VVJ1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O35932-1", "protein_name": "Prostaglandin D2 receptor-like", "gene_name": "Ptgdrl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNESYRCQAATWVERGSSATMGGVLFSAGLLGNLLALVLLARSGLGSCRPGPLHPPPSVFYVLVCGLTVTHLLGKCLISPMVLAAYAQNRSLKELLPASGNQLCEAFAFLMSFFGLASTLQLLAMALECWLSLGHPFFYQRHITARRGVLVAPVAGAFSLAFCALPFAGFGKFVQYCPGTWCFIQMIHKKRSFSVIGFSVLYSSLMALLVLATVVCNLGAMSNLYAMHRRQRHHPRRCSRDRAQSGSDYRHGSPNPLEELDHFVLLALTTVLFTMCSLPLIYRAYYGAFKLVDRADGDSEDLQALRFLSVISIVDPWIFIIFRTSVFRMLFHKAFTRPLIYRNWCSHSWQTNMESTL", "length": 357 }, "evidence": [ { "id": "RGD:619707", "url": "https://alliancegenome.org/gene/RGD:619707#orthology", "database": "AGR" }, { "id": "HGNC:9591", "url": "https://alliancegenome.org/gene/HGNC:9591#orthology", "database": "AGR" }, { "id": "MGI:102966", "url": "https://alliancegenome.org/gene/MGI:102966#orthology", "database": "AGR" }, { "id": "RGD:1565108", "url": "https://alliancegenome.org/gene/RGD:1565108#orthology", "database": "AGR" }, { "id": "FB:FBgn0036742", "url": "https://alliancegenome.org/gene/FB:FBgn0036742#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P21731-3", "protein_name": "Thromboxane A2 receptor", "gene_name": "TBXA2R", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWNQILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ", "length": 343 }, "evidence": [ { "id": "HGNC:11608", "url": "https://alliancegenome.org/gene/HGNC:11608#orthology", "database": "AGR" }, { "id": "MGI:98496", "url": "https://alliancegenome.org/gene/MGI:98496#orthology", "database": "AGR" }, { "id": "RGD:3825", "url": "https://alliancegenome.org/gene/RGD:3825#orthology", "database": "AGR" }, { "id": "FB:FBgn0036742", "url": "https://alliancegenome.org/gene/FB:FBgn0036742#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P30557-1", "protein_name": "Prostaglandin E2 receptor EP3 subtype", "gene_name": "Ptger3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASMWAPEHSAEAHSNLSSTTDDCGSVSVAFPITMMVTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTSPVVILVYLSQRRWEQLDPSGRLCTFFGLTMTVFGLSSLLVASAMAVERALAIRAPHWYASHMKTRATPVLLGVWLSVLAFALLPVLGVGRYSVQWPGTWCFISTGPAGNETDPAREPGSVAFASAFACLGLLALVVTFACNLATIKALVSRCRAKAAVSQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLIMMLKMIFNQMSVEQCKTQMGKEKECNSFLIAVRLASLNQILDPWVYLLLRKILLRKFCQIRDHTNYASSSTSLPCPGSSALMWSDQLER", "length": 365 }, "evidence": [ { "id": "HGNC:9595", "url": "https://alliancegenome.org/gene/HGNC:9595#orthology", "database": "AGR" }, { "id": "MGI:97795", "url": "https://alliancegenome.org/gene/MGI:97795#orthology", "database": "AGR" }, { "id": "RGD:3435", "url": "https://alliancegenome.org/gene/RGD:3435#orthology", "database": "AGR" }, { "id": "FB:FBgn0036742", "url": "https://alliancegenome.org/gene/FB:FBgn0036742#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P30987-1", "protein_name": "Thromboxane A2 receptor", "gene_name": "Tbxa2r", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWPNGTSLGACFRPVNITLQERRAIASPWFAASFCALGLGSNLLALSVLAGARPGAGPRSSFLALLCGLVLTDFLGLLVTGAIVASQHAALLDWRATDPSCRLCYFMGVAMVFFGLCPLLLGAAMASERFVGITRPFSRPTATSRRAWATVGLVWVAAGALGLLPLLGLGRYSVQYPGSWCFLTLGTQRGDVVFGLIFALLGSASVGLSLLLNTVSVATLCRVYHTREATQRPRDCEVEMMVQLVGIMVVATVCWMPLLVFIMQTLLQTPPVMSFSGQLLRATEHQLLIYLRVATWNQILDPWVYILFRRSVLRRLHPRFSSQLQAVSLRRPPAQAMLSGP", "length": 341 }, "evidence": [ { "id": "HGNC:11608", "url": "https://alliancegenome.org/gene/HGNC:11608#orthology", "database": "AGR" }, { "id": "MGI:98496", "url": "https://alliancegenome.org/gene/MGI:98496#orthology", "database": "AGR" }, { "id": "RGD:3825", "url": "https://alliancegenome.org/gene/RGD:3825#orthology", "database": "AGR" }, { "id": "FB:FBgn0036742", "url": "https://alliancegenome.org/gene/FB:FBgn0036742#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P32240-1", "protein_name": "Prostaglandin E2 receptor EP4 subtype", "gene_name": "Ptger4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEVGGTIPRSNRELQRCVLLTTTIMSIPGVNASFSSTPERLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCGLAVTDLLGTLLVSPVTIATYMKGQWPGDQALCDYSTFILLFFGLSGLSIICAMSIERYLAINHAYFYSHYVDKRLAGLTLFAIYASNVLFCALPNMGLGRSERQYPGTWCFIDWTTNVTAYAAFSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAAAVASVACRGHAGASPALQRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFINQLYQPNVVKDISRNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRIGGSGRDSSAQHCSESRRTSSAMSGHSRSFLARELKEISSTSQTLLYLPDLTESSLGGRNLLPGSHGMGLTQADTTSLRTLRISETSDSSQGQDSESVLLVDEVSGSHREEPASKGNSLQVTFPSETLKLSEKCI", "length": 513 }, "evidence": [ { "id": "HGNC:9596", "url": "https://alliancegenome.org/gene/HGNC:9596#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060222-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060222-1#orthology", "database": "AGR" }, { "id": "MGI:104311", "url": "https://alliancegenome.org/gene/MGI:104311#orthology", "database": "AGR" }, { "id": "RGD:628641", "url": "https://alliancegenome.org/gene/RGD:628641#orthology", "database": "AGR" }, { "id": "FB:FBgn0036742", "url": "https://alliancegenome.org/gene/FB:FBgn0036742#orthology", "database": "AGR" }, { "id": "Q9VVJ1", "url": "https://omabrowser.org/oma/group/Q9VVJ1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P34978-1", "protein_name": "Thromboxane A2 receptor", "gene_name": "Tbxa2r", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWLNSTSLGACFRPVNITLQERRAIASPWFAASFCALGLGSNLLALSVLAGARPGAGPRSSFLALLCGLVLTDFLGLLVTGAVVASQHAALLDWRATDPGCRLCHFMGAAMVFFGLCPLLLGAAMAAERFVGITRPFSRPAATSRRAWATVGLVWVGAGTLGLLPLLGLGRYSVQYPGSWCFLTLGAERGDVAFGLMFALLGSVSVGLSLLLNTVSVATLCRVYHAREATQRPRDCEVEMMVQLVGIMVVATVCWMPLLVFILQTLLQTLPVMSPSGQLLRTTERQLLIYLRVATWNQILDPWVYILFRRSVLRRLHPRFTSQLQAVSLHSPPTQAMLSGP", "length": 341 }, "evidence": [ { "id": "HGNC:11608", "url": "https://alliancegenome.org/gene/HGNC:11608#orthology", "database": "AGR" }, { "id": "MGI:98496", "url": "https://alliancegenome.org/gene/MGI:98496#orthology", "database": "AGR" }, { "id": "RGD:3825", "url": "https://alliancegenome.org/gene/RGD:3825#orthology", "database": "AGR" }, { "id": "FB:FBgn0036742", "url": "https://alliancegenome.org/gene/FB:FBgn0036742#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P34980-1", "protein_name": "Prostaglandin E2 receptor EP3 subtype", "gene_name": "Ptger3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGVWAPEHSVEAHSNQSSAADGCGSVSVAFPITMMVTGFVGNALAMLLVVRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTSPVVILVYLSQRRWEQLDPSGRLCTFFGLTMTVFGLSSLLVASAMAVERALAIRAPHWYASHMKTRATPVLLGVWLSVLAFALLPVLGVGRYSVQWPGTWCFISTGPAGNETDSAREPGSVAFASAFACLGLLALVVTFACNLATIKALVSRCRAKAAASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLIMMLKMIFNQMSVEQCKTQMGKEKECNSFLIAVRLASLNQILDPWVYLLLRKILLRKFCQIRDHTNYASSSTSLPCPGSSVLMWSDQLER", "length": 365 }, "evidence": [ { "id": "HGNC:9595", "url": "https://alliancegenome.org/gene/HGNC:9595#orthology", "database": "AGR" }, { "id": "MGI:97795", "url": "https://alliancegenome.org/gene/MGI:97795#orthology", "database": "AGR" }, { "id": "RGD:3435", "url": "https://alliancegenome.org/gene/RGD:3435#orthology", "database": "AGR" }, { "id": "FB:FBgn0036742", "url": "https://alliancegenome.org/gene/FB:FBgn0036742#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P34995-1", "protein_name": "Prostaglandin E2 receptor EP1 subtype", "gene_name": "PTGER1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSPCGPLNLSLAGEATTCAAPWVPNTSAVPPSGASPALPIFSMTLGAVSNLLALALLAQAAGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVALAVALLPLARVGRYELQYPGTWCFIGLGPPGGWRQALLAGLFASLGLVALLAALVCNTLSGLALLRARWRRRSRRPPPASGPDSRRRWGAHGPRSASASSASSIASASTFFGGSRSSGSARRARAHDVEMVGQLVGIMVVSCICWSPMLVLVALAVGGWSSTSLQRPLFLAVRLASWNQILDPWVYILLRQAVLRQLLRLLPPRAGAKGGPAGLGLTPSAWEASSLRSSRHSGLSHF", "length": 402 }, "evidence": [ { "id": "HGNC:9593", "url": "https://alliancegenome.org/gene/HGNC:9593#orthology", "database": "AGR" }, { "id": "MGI:97793", "url": "https://alliancegenome.org/gene/MGI:97793#orthology", "database": "AGR" }, { "id": "RGD:3434", "url": "https://alliancegenome.org/gene/RGD:3434#orthology", "database": "AGR" }, { "id": "FB:FBgn0036742", "url": "https://alliancegenome.org/gene/FB:FBgn0036742#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P35375-1", "protein_name": "Prostaglandin E2 receptor EP1 subtype", "gene_name": "Ptger1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSPCGLNLSLADEAATCATPRLPNTSVVLPTGDNGTSPALPIFSMTLGAVSNVLALALLAQVAGRMRRRRSAATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALAVLAAMALAVALLPLVHVGRYELQYPGTWCFISLGPRGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRKTAGPDDRRRWGSRGPRLASASSASSITSATATLRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELGLTKSAWEASSLRSSRHSGFSHL", "length": 405 }, "evidence": [ { "id": "HGNC:9593", "url": "https://alliancegenome.org/gene/HGNC:9593#orthology", "database": "AGR" }, { "id": "MGI:97793", "url": "https://alliancegenome.org/gene/MGI:97793#orthology", "database": "AGR" }, { "id": "RGD:3434", "url": "https://alliancegenome.org/gene/RGD:3434#orthology", "database": "AGR" }, { "id": "FB:FBgn0036742", "url": "https://alliancegenome.org/gene/FB:FBgn0036742#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P35408-1", "protein_name": "Prostaglandin E2 receptor EP4 subtype", "gene_name": "PTGER4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSTPGVNSSASLSPDRLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCGLAVTDLLGTLLVSPVTIATYMKGQWPGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLAINHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFIDWTTNVTAHAAYSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRGHPAASPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLYQPSLEREVSKNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRIGGSRRERSGQHCSDSQRTSSAMSGHSRSFISRELKEISSTSQTLLPDLSLPDLSENGLGGRNLLPGVPGMGLAQEDTTSLRTLRISETSDSSQGQDSESVLLVDEAGGSGRAGPAPKGSSLQVTFPSETLNLSEKCI", "length": 488 }, "evidence": [ { "id": "HGNC:9596", "url": "https://alliancegenome.org/gene/HGNC:9596#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060222-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060222-1#orthology", "database": "AGR" }, { "id": "MGI:104311", "url": "https://alliancegenome.org/gene/MGI:104311#orthology", "database": "AGR" }, { "id": "RGD:628641", "url": "https://alliancegenome.org/gene/RGD:628641#orthology", "database": "AGR" }, { "id": "FB:FBgn0036742", "url": "https://alliancegenome.org/gene/FB:FBgn0036742#orthology", "database": "AGR" }, { "id": "Q9VVJ1", "url": "https://omabrowser.org/oma/group/Q9VVJ1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43088-1", "protein_name": "Prostaglandin F2-alpha receptor", "gene_name": "PTGFR", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSMNNSKQLVSPAAALLSNTTCQTENRLSVFFSVIFMTVGILSNSLAIAILMKAYQRFRQKSKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVFSGLCPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVFIALLPILGHRDYKIQASRTWCFYNTEDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLLRVKFKSQQHRQGRSHHLEMVIQLLAIMCVSCICWSPFLVTMANIGINGNHSLETCETTLFALRMATWNQILDPWVYILLRKAVLKNLYKLASQCCGVHVISLHIWELSSIKNSLKVAAISESPVAEKSAST", "length": 359 }, "evidence": [ { "id": "HGNC:9600", "url": "https://alliancegenome.org/gene/HGNC:9600#orthology", "database": "AGR" }, { "id": "MGI:97796", "url": "https://alliancegenome.org/gene/MGI:97796#orthology", "database": "AGR" }, { "id": "RGD:3436", "url": "https://alliancegenome.org/gene/RGD:3436#orthology", "database": "AGR" }, { "id": "FB:FBgn0036742", "url": "https://alliancegenome.org/gene/FB:FBgn0036742#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43114-1", "protein_name": "Prostaglandin E2 receptor EP4 subtype", "gene_name": "Ptger4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSIPGVNASFSSTPERLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCGLAVTDLLGTLLVSPVTIATYMKGQWPGDQALCDYSTFILLFFGLSGLSIICAMSIERYLAINHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGRSERQYPGTWCFIDWTTNVTAYAAFSYMYAGFSSFLILATVLCNVLVCGALLRMLRQFMRRTSLGTEQHHAAAAAAVASVACRGHAAASPALQRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFINQLYQPSVVKDISRNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRIGGSGRDGSAQHCSESRRTSSAMSGHSRSFLSRELREISSTSHTLLYLPDLTESSLGGKNLLPGTHGMGLTQADTTSLRTLRISETSDSSQGQDSESVLLVDEVSGSQREEPASKGNSLQVTFPSETLKLSEKCI", "length": 488 }, "evidence": [ { "id": "HGNC:9596", "url": "https://alliancegenome.org/gene/HGNC:9596#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060222-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060222-1#orthology", "database": "AGR" }, { "id": "MGI:104311", "url": "https://alliancegenome.org/gene/MGI:104311#orthology", "database": "AGR" }, { "id": "RGD:628641", "url": "https://alliancegenome.org/gene/RGD:628641#orthology", "database": "AGR" }, { "id": "FB:FBgn0036742", "url": "https://alliancegenome.org/gene/FB:FBgn0036742#orthology", "database": "AGR" }, { "id": "Q9VVJ1", "url": "https://omabrowser.org/oma/group/Q9VVJ1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P43115-1", "protein_name": "Prostaglandin E2 receptor EP3 subtype", "gene_name": "PTGER3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRWEHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLGVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLLALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLIMMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQIRYHTNNYASSSTSLPCQCSSTLMWSDHLER", "length": 390 }, "evidence": [ { "id": "HGNC:9595", "url": "https://alliancegenome.org/gene/HGNC:9595#orthology", "database": "AGR" }, { "id": "MGI:97795", "url": "https://alliancegenome.org/gene/MGI:97795#orthology", "database": "AGR" }, { "id": "RGD:3435", "url": "https://alliancegenome.org/gene/RGD:3435#orthology", "database": "AGR" }, { "id": "FB:FBgn0036742", "url": "https://alliancegenome.org/gene/FB:FBgn0036742#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43116-1", "protein_name": "Prostaglandin E2 receptor EP2 subtype", "gene_name": "PTGER2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGNASNDSQSEDCETRQWLPPGESPAISSVMFSAGVLGNLIALALLARRWRGDVGCSAGRRSSLSLFHVLVTELVFTDLLGTCLISPVVLASYARNQTLVALAPESRACTYFAFAMTFFSLATMLMLFAMALERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQYCPGTWCFIRHGRTAYLQLYATLLLLLIVSVLACNFSVILNLIRMHRRSRRSRCGPSLGSGRGGPGARRRGERVSMAEETDHLILLAIMTITFAVCSLPFTIFAYMNETSSRKEKWDLQALRFLSINSIIDPWVFAILRPPVLRLMRSVLCCRISLRTQDATQTSCSTQSDASKQADL", "length": 358 }, "evidence": [ { "id": "HGNC:9594", "url": "https://alliancegenome.org/gene/HGNC:9594#orthology", "database": "AGR" }, { "id": "MGI:97794", "url": "https://alliancegenome.org/gene/MGI:97794#orthology", "database": "AGR" }, { "id": "RGD:620020", "url": "https://alliancegenome.org/gene/RGD:620020#orthology", "database": "AGR" }, { "id": "FB:FBgn0036742", "url": "https://alliancegenome.org/gene/FB:FBgn0036742#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43117-1", "protein_name": "Prostaglandin F2-alpha receptor", "gene_name": "Ptgfr", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMNSSKQPVSPAAGLIANTTCQTENRLSVFFSIIFMTVGILSNSLAIAILMKAYQRFRQKSKASFLLLASGLVITDFFGHLINGGIAVFVYASDKDWIRFDQSNILCSIFGISMVFSGLCPLFLGSAMAIERCIGVTNPIFHSTKITSKHVKMILSGVCMFAVFVAVLPILGHRDYQIQASRTWCFYNTEHIEDWEDRFYLLFFSFLGLLALGVSFSCNAVTGVTLLRVKFRSQQHRQGRSHHLEMIIQLLAIMCVSCVCWSPFLVTMANIAINGNNSPVTCETTLFALRMATWNQILDPWVYILLRKAVLRNLYKLASRCCGVNIISLHIWELSSIKNSLKVAAISESPAAEKESQQASSEAGL", "length": 366 }, "evidence": [ { "id": "HGNC:9600", "url": "https://alliancegenome.org/gene/HGNC:9600#orthology", "database": "AGR" }, { "id": "MGI:97796", "url": "https://alliancegenome.org/gene/MGI:97796#orthology", "database": "AGR" }, { "id": "RGD:3436", "url": "https://alliancegenome.org/gene/RGD:3436#orthology", "database": "AGR" }, { "id": "FB:FBgn0036742", "url": "https://alliancegenome.org/gene/FB:FBgn0036742#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P43118-1", "protein_name": "Prostaglandin F2-alpha receptor", "gene_name": "Ptgfr", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSINSSKQPASSAAGLIANTTCQTENRLSVFFSIIFMTVGIVSNSLAIAILMKAYQRFRRKSKASFLLLASGLVITDFFGHLINGGIAVFVYASDKDWIRFDQSNILCSVFGISMVFSGLCPLFLGSTMAIERCIGVTNPLFHSTKITSKHVKMILSGVCMFAVFVALLPILGHRDYQIQASRTWCFYNTEHIEDWEDRFYLLFFSSLGLLALGISFSCNAVTGVTLLRVKFRSQQHRQGRSHHLEMVIQLLAIMCVSCVCWSPFLVTMANIAINGNNSPVTCETTLFALRMATWNQILDPWVYILLRKAVLRNLYKLASRCCGVNIISLHIWELSSIKNSLKVAAISESPAAEKENQQASSEAGL", "length": 366 }, "evidence": [ { "id": "HGNC:9600", "url": "https://alliancegenome.org/gene/HGNC:9600#orthology", "database": "AGR" }, { "id": "MGI:97796", "url": "https://alliancegenome.org/gene/MGI:97796#orthology", "database": "AGR" }, { "id": "RGD:3436", "url": "https://alliancegenome.org/gene/RGD:3436#orthology", "database": "AGR" }, { "id": "FB:FBgn0036742", "url": "https://alliancegenome.org/gene/FB:FBgn0036742#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P43119-1", "protein_name": "Prostacyclin receptor", "gene_name": "PTGIR", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADSCRNLTYVRGSVGPATSTLMFVAGVVGNGLALGILSARRPARPSAFAVLVTGLAATDLLGTSFLSPAVFVAYARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLALSHPYLYAQLDGPRCARLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRMRWAQPGGAAFSLAYAGLVALLVAAIFLCNGSVTLSLCRMYRQQKRHQGSLGPRPRTGEDEVDHLILLALMTVVMAVCSLPLTIRCFTQAVAPDSSSEMGDLLAFRFYAFNPILDPWVFILFRKAVFQRLKLWVCCLCLGPAHGDSQTPLSQLASGRRDPRAPSAPVGKEGSCVPLSAWGEGQVEPLPPTQQSSGSAVGTSSKAEASVACSLC", "length": 386 }, "evidence": [ { "id": "HGNC:9602", "url": "https://alliancegenome.org/gene/HGNC:9602#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120511-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120511-1#orthology", "database": "AGR" }, { "id": "MGI:99535", "url": "https://alliancegenome.org/gene/MGI:99535#orthology", "database": "AGR" }, { "id": "RGD:1310890", "url": "https://alliancegenome.org/gene/RGD:1310890#orthology", "database": "AGR" }, { "id": "FB:FBgn0036742", "url": "https://alliancegenome.org/gene/FB:FBgn0036742#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43252-1", "protein_name": "Prostacyclin receptor", "gene_name": "Ptgir", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMASDGHPGPPSVTPGSPLSAGGREWQGMAGSCWNITYVQDSVGPATSTLMFVAGVVGNGLALGILGARRRSHPSAFAVLVTGLAVTDLLGTCFLSPAVFVAYARNSSLLGLAHGGTMLCDTFAFAMTFFGLASTLILFAMAVERCLALSHPYLYAQLDGPRCARFALPSIYAFCCLFCSLPLLGLGEHQQYCPGSWCFIRMRSAQPGGCAFSLAYASLMALLVTSIFFCNGSVTLSLYHMYRQQRRHHGSFVPTSRAREDEVYHLILLALMTVIMAVCSLPLMIRGFTQAIAPDSREMGDLLAFRFNAFNPILDPWVFILFRKAVFQRLKFWLCCLCARSVHGDLQAPLSRPASGRRDPPAPTSLQAKEGSWVPLSSWGTGQVAPLTAVPLTGGDGCSVGMPSKSEAIAACSLC", "length": 415 }, "evidence": [ { "id": "HGNC:9602", "url": "https://alliancegenome.org/gene/HGNC:9602#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120511-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120511-1#orthology", "database": "AGR" }, { "id": "MGI:99535", "url": "https://alliancegenome.org/gene/MGI:99535#orthology", "database": "AGR" }, { "id": "RGD:1310890", "url": "https://alliancegenome.org/gene/RGD:1310890#orthology", "database": "AGR" }, { "id": "FB:FBgn0036742", "url": "https://alliancegenome.org/gene/FB:FBgn0036742#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P43253-1", "protein_name": "Prostacyclin receptor", "gene_name": "Ptgir", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVASGGRPDGPPSITPESPLIVGGREWQGMAGSCWNITYVQDSVGPATSTLMFVAGVVGNGLALGILGARRRSHPSAFAVLVTGLAVTDLLGTCFLSPAVFVAYARNSSLLGLAHGGTMLCDTFAFAMTFFGLASTLILFAMAVERCLALSHPYLYAQLDGPRCARLALPAIYAFCCLFCSLPLLGLGEHQQYCPGSWCFIRMRSPQPGGCAFSLAYASLMALLVTSIFFCNGSVTLSLCHMYRQQRRHHGSFVPTSRAREDEVYHLILLALMTGIMAVCSLPLTIRGFTQAIAPDSREMGDLHAFRFNAFNPILDPWVFILFRKAVFQRLKFWLCCLCARSVHGDLQTPLSRPVSGRRDTLAPDSLQAKEGNWVPLSTWGTGQVAPLTAVPLSGGDGCSVGMPSKTEAVVACSLC", "length": 416 }, "evidence": [ { "id": "HGNC:9602", "url": "https://alliancegenome.org/gene/HGNC:9602#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120511-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120511-1#orthology", "database": "AGR" }, { "id": "MGI:99535", "url": "https://alliancegenome.org/gene/MGI:99535#orthology", "database": "AGR" }, { "id": "RGD:1310890", "url": "https://alliancegenome.org/gene/RGD:1310890#orthology", "database": "AGR" }, { "id": "FB:FBgn0036742", "url": "https://alliancegenome.org/gene/FB:FBgn0036742#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P70263-1", "protein_name": "Prostaglandin D2 receptor", "gene_name": "Ptgdr", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNESYRCQTSTWVERGSSATMGAVLFGAGLLGNLLALVLLARSGLGSCRPGPLHPPPSVFYVLVCGLTVTDLLGKCLISPMVLAAYAQNQSLKELLPASGNQLCETFAFLMSFFGLASTLQLLAMAVECWLSLGHPFFYQRHVTLRRGVLVAPVVAAFCLAFCALPFAGFGKFVQYCPGTWCFIQMIHKERSFSVIGFSVLYSSLMALLVLATVVCNLGAMYNLYDMHRRQRHYPHRCSRDRAQSGSDYRHGSLHPLEELDHFVLLALMTVLFTMCSLPLIYRAYYGAFKLENKAEGDSEDLQALRFLSVISIVDPWIFIIFRTSVFRMLFHKVFTRPLIYRNWSSHSQQSNVESTL", "length": 357 }, "evidence": [ { "id": "RGD:619707", "url": "https://alliancegenome.org/gene/RGD:619707#orthology", "database": "AGR" }, { "id": "HGNC:9591", "url": "https://alliancegenome.org/gene/HGNC:9591#orthology", "database": "AGR" }, { "id": "MGI:102966", "url": "https://alliancegenome.org/gene/MGI:102966#orthology", "database": "AGR" }, { "id": "RGD:1565108", "url": "https://alliancegenome.org/gene/RGD:1565108#orthology", "database": "AGR" }, { "id": "FB:FBgn0036742", "url": "https://alliancegenome.org/gene/FB:FBgn0036742#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P70597-1", "protein_name": "Prostaglandin E2 receptor EP1 subtype", "gene_name": "Ptger1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL", "length": 405 }, "evidence": [ { "id": "HGNC:9593", "url": "https://alliancegenome.org/gene/HGNC:9593#orthology", "database": "AGR" }, { "id": "MGI:97793", "url": "https://alliancegenome.org/gene/MGI:97793#orthology", "database": "AGR" }, { "id": "RGD:3434", "url": "https://alliancegenome.org/gene/RGD:3434#orthology", "database": "AGR" }, { "id": "FB:FBgn0036742", "url": "https://alliancegenome.org/gene/FB:FBgn0036742#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q13258-1", "protein_name": "Prostaglandin D2 receptor", "gene_name": "PTGDR", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKSPFYRCQNTTSVEKGNSAVMGGVLFSTGLLGNLLALGLLARSGLGWCSRRPLRPLPSVFYMLVCGLTVTDLLGKCLLSPVVLAAYAQNRSLRVLAPALDNSLCQAFAFFMSFFGLSSTLQLLAMALECWLSLGHPFFYRRHITLRLGALVAPVVSAFSLAFCALPFMGFGKFVQYCPGTWCFIQMVHEEGSLSVLGYSVLYSSLMALLVLATVLCNLGAMRNLYAMHRRLQRHPRSCTRDCAEPRADGREASPQPLEELDHLLLLALMTVLFTMCSLPVIYRAYYGAFKDVKEKNRTSEEAEDLRALRFLSVISIVDPWIFIIFRSPVFRIFFHKIFIRPLRYRSRCSNSTNMESSL", "length": 359 }, "evidence": [ { "id": "RGD:619707", "url": "https://alliancegenome.org/gene/RGD:619707#orthology", "database": "AGR" }, { "id": "HGNC:9591", "url": "https://alliancegenome.org/gene/HGNC:9591#orthology", "database": "AGR" }, { "id": "MGI:102966", "url": "https://alliancegenome.org/gene/MGI:102966#orthology", 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"database": "UniProtKB", "id": "Q9VVJ1", "url": "https://www.uniprot.org/uniprotkb/Q9VVJ1" } ], "pmid": "" }, { "name": "prostaglandin D receptor activity", "id": "GO:0004956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004956", "evidence": [ { "database": "UniProtKB", "id": "Q9VVJ1", "url": "https://www.uniprot.org/uniprotkb/Q9VVJ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 15, "end_pos": 17, "annotation": "n_glycosylation_sequon" }, { "start_pos": 195, "end_pos": 197, "annotation": "n_glycosylation_sequon" }, { "start_pos": 370, "end_pos": 372, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VVJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVJ1" }, { "id": "PS50262", "database": "PROSITE", "url": 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{ "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VVK5-1", "uniprot_ac": "Q9VVK5", "uniprot_id": "Q9VVK5_DROME", 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}, { "id": "Q9VVK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVK5" } ] }, { "name": "Dmel\\CG5992", "type": "synonym", "evidence": [ { "id": "NP_524130", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524130" }, { "id": "Q9VVK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVK5" } ] }, { "name": "Dmel_CG5992", "type": "synonym", "evidence": [ { "id": "Q9VVK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVK5" } ] }, { "name": "adgf-a", "type": "synonym", "evidence": [ { "id": "NP_524130", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524130" }, { "id": "Q9VVK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVK5" } ] }, { "name": "adgfa", "type": "synonym", "evidence": [ { "id": "NP_524130", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524130" }, { "id": "Q9VVK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVK5" } ] } ], "protein_names": [ { "name": "Adenosine deaminase", "type": "recommended", "evidence": [ { "id": "Q9VVK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVK5/entry#names_and_taxonomy" } ] }, { "name": "3.5.4.4", "type": "synonym", "evidence": [ { "id": "Q9VVK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVK5/entry#names_and_taxonomy" } ] }, { "name": "Adgf-A-PA", "type": "synonym", "evidence": [ { "id": "NP_524130", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524130" } ] }, { "name": "Ado deaminase growth factor-A", "type": "synonym", "evidence": [ { "id": "NP_524130", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524130" } ] }, { "name": "CG5992-PA", "type": "synonym", "evidence": [ { "id": "NP_524130", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524130" } ] }, { "name": "adenosine deaminase growth Factor-A", 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This results from an allergic response to tuberculoprotein causing the permeabiltity of the pleural vasculature to alter leading to a sub-pleural caseous focus rupture into the pleural sac." }, "synonyms": [ { "id": "DOID:106", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:106", "name": "Pearly disease", "description": "" }, { "id": "DOID:106", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:106", "name": "Tuberculosis of pleura", "description": "" }, { "id": "DOID:106", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:106", "name": "Tuberculous pleurisy", "description": "" }, { "id": "DOID:106", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:106", "name": "Tuberculous pleuritis", "description": "" }, { "id": "DOID:106", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:106", "name": "tuberculous pleurisy in primary progressive tuberculosis", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "106", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:106" } ] }, { "disease_id": "DOID:13096", "recommended_name": { "id": "DOID:13096", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13096", "name": "Sneddon syndrome", "description": "An artery disease that is characterized by onset of livedo reticularis in the second decade and onset of cerebrovascular disease in early adulthood and that has_material_basis_in compound heterozygous mutation in the CECR1 gene (ADA2) on chromosome 22q11." }, "synonyms": [ { "id": "DOID:13096", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13096", "name": "Idiopathic livedo reticularis with systemic involvement", "description": "" }, { "id": "MONDO:0008436", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008436", "name": "Sneddon syndrome", "description": "Sneddon's syndrome (SS) is a rare non-inflammatory thrombotic vasculopathy characterized by the combination of cerebrovascular disease with livedo racemosa." }, { "id": "MONDO:0008436", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008436", "name": "Ehrmann-Sneddon syndrome", "description": "" }, { "id": "MONDO:0008436", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008436", "name": "Sneddon syndrome", "description": "" }, { "id": "MONDO:0008436", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008436", "name": "livedo racemosa-cerebrovascular accident syndrome", "description": "" }, { "id": "MONDO:0008436", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008436", "name": "livedo reticularis-cerebrovascular accident syndrome", "description": "" }, { "id": "MONDO:0008436", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008436", "name": "Sneddon's syndrome", "description": "" }, { "id": "MONDO:0008436", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008436", "name": "cerebro-vascular lesions and livedo reticularis", "description": "" }, { "id": "MONDO:0008436", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008436", "name": "livedo racemosa and cerebrovascular accidents", "description": "" }, { "id": "MIM:182410", "resource": "MIM", "url": "https://www.omim.org/entry/182410", "name": "Sneddon syndrome", "description": "Sneddon syndrome" } ], "unlinked_id_list": [], "evidence": [ { "id": "13096", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13096" } ] }, { "disease_id": "DOID:2957", "recommended_name": { "id": "DOID:2957", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2957", "name": "pulmonary tuberculosis", "description": "A tuberculosis that is a contagious disease located_in lungs. The infection has_symptom fever, has_symptom cough, has_symptom difficulty in breathing, has_symptom inflammatory infiltrations, has_symptom formation of tubercles, has_symptom caseation, has_symptom pleural effusion, and has_symptom fibrosis." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "2957", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2957" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VVK5", "url": "https://www.uniprot.org/uniprotkb/Q9VVK5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Adgf-A", "url": "https://www.uniprot.org/uniprotkb/Q9VVK5", "locus": { "chromosome": "3L", "start_pos": 17751731, "end_pos": 17764158, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0036752", "url": "https://www.ensemblgenomes.org/id/FBgn0036752" } ] } } ], "crossref": [ { "id": "FB:FBgn0036752", "url": "https://alliancegenome.org/gene/FB:FBgn0036752", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0036752", "url": "https://bgee.org/?page=gene&gene_id=FBgn0036752", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01321", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01321", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0036752", "url": "https://flybase.org/reports/FBgn0036752", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "39976", "url": "https://www.ncbi.nlm.nih.gov/gene/39976", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001365", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001365", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006330", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006330", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013659", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013659", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032466", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032466", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG5992", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG5992", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FQACFGP", "url": "https://omabrowser.org/oma/group/FQACFGP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VVK5", "url": "https://www.orthodb.org/?gene=Q9VVK5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11409", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11409", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11409:SF39", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11409:SF39", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00962", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00962", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08451", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08451", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_524130", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524130", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "24408", "url": "https://www.rhea-db.org/rhea/24408", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q9VVK5", "url": "https://www.uniprot.org/uniprotkb/Q9VVK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VVK5-1", "url": "https://www.uniprot.org/uniprotkb/Q9VVK5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSPVIRRNLIACLTLGLCVCLSFGPGPVESRTRPKNQVDRKLLTIYGSTPHVEALLGPGRPTPDTYKTLRSAFFRYEESRSLGHDLDLNSREIKANETIMKAKLKEFDEGLVTPHLFKPSQHIFDVLDGIRNTDLFKLLKKMPKGAVLHAHDTALCSTAAIINLTYYEHLWSCQQDGDLSASALRFSKDKPQALSDCDWSLLSDVRAKYGADKVDDYLAERLTLYPTKKFEDNNAAWSTFMSIFNLLDGLVMYAPVWADYYYKALEEFYEDGVLYLEFRSVVPTLYDMDGTEFTPMDTVRIYVETLEKFKEAHPDFIGSRMIYAPIRYTNAEGVTGYIQTLKQIKEKYPEFVAGFDLVGQEEMGRPLRDFVDELLSIPDDIDFYFHAGETNWFGSTVDENLIDAILLGTKRIGHGFGLVKHPVVLDMLKKLNVAIEVNPISNQVLQLVSDFRNHPCSHFFADGYPVVISSDDPSFWKATPLTHDFYIAFLGIASQHSDLRLLKKLALNSIQYSSLTGDAQFEALEKWQVKWDQFIADVNDRSSNRGSPSQRID", "length": 553, "header": "tr|Q9VVK5-1|Q9VVK5_DROME Isoform 1 of Adenosine deaminase OS=Drosophila melanogaster OX=7227 GN=Adgf-A PE=1 SV=1 CANONICAL=Q9VVK5-1" }, "isoforms": [ { "isoform_ac": "Q9VVK5-1", "url": "https://www.uniprot.org/uniprotkb/Q9VVK5/entry#Q9VVK5-1", "sequence": { "sequence": "MSPVIRRNLIACLTLGLCVCLSFGPGPVESRTRPKNQVDRKLLTIYGSTPHVEALLGPGRPTPDTYKTLRSAFFRYEESRSLGHDLDLNSREIKANETIMKAKLKEFDEGLVTPHLFKPSQHIFDVLDGIRNTDLFKLLKKMPKGAVLHAHDTALCSTAAIINLTYYEHLWSCQQDGDLSASALRFSKDKPQALSDCDWSLLSDVRAKYGADKVDDYLAERLTLYPTKKFEDNNAAWSTFMSIFNLLDGLVMYAPVWADYYYKALEEFYEDGVLYLEFRSVVPTLYDMDGTEFTPMDTVRIYVETLEKFKEAHPDFIGSRMIYAPIRYTNAEGVTGYIQTLKQIKEKYPEFVAGFDLVGQEEMGRPLRDFVDELLSIPDDIDFYFHAGETNWFGSTVDENLIDAILLGTKRIGHGFGLVKHPVVLDMLKKLNVAIEVNPISNQVLQLVSDFRNHPCSHFFADGYPVVISSDDPSFWKATPLTHDFYIAFLGIASQHSDLRLLKKLALNSIQYSSLTGDAQFEALEKWQVKWDQFIADVNDRSSNRGSPSQRID", "length": 553, "header": "tr|Q9VVK5-1|Q9VVK5_DROME Isoform 1 of Adenosine deaminase OS=Drosophila melanogaster OX=7227 GN=Adgf-A PE=1 SV=1 CANONICAL=Q9VVK5-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 62, "start_aa": "Thr", "end_pos": 62, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr62", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VVK5", "url": "https://www.uniprot.org/uniprotkb/Q9VVK5" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VVK5", "url": "https://www.uniprot.org/uniprotkb/Q9VVK5" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVK5", "url": "https://www.uniprot.org/uniprotkb/Q9VVK5" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVK5", "url": "https://www.uniprot.org/uniprotkb/Q9VVK5" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VVK5", "url": "https://www.uniprot.org/uniprotkb/Q9VVK5" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VVK5", "url": "https://www.uniprot.org/uniprotkb/Q9VVK5" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VVK5", "url": "https://www.uniprot.org/uniprotkb/Q9VVK5" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVK5", "url": "https://www.uniprot.org/uniprotkb/Q9VVK5" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVK5", "url": "https://www.uniprot.org/uniprotkb/Q9VVK5" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VVK5", "url": "https://www.uniprot.org/uniprotkb/Q9VVK5" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VVK5", "url": "https://www.uniprot.org/uniprotkb/Q9VVK5" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG5992", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG5992", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ACD6B6N6-1", "protein_name": "adenosine deaminase", "gene_name": "ada2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSSISLKDVSAAVMVVLLVCVSECKSMPDPRQREQMLQQELLQQIGGNMELNEAEKRMDSLLYMLKMKEITLSPFPPANHFFKVRHIIQQSPIFKLLQKMPKGAALHIHNSAMVSVDWLLNATYRPNCYICFTWDGSVRFTFSTSTPFPRWGCSFWKRLDILRASLGDVTSFDNSLMRNLTLFTEDPETSYPTQDCIWKRFEKIFIALSGLITYAPVLKDHIYQGLKELYEDNIMYVELRIGQAKAYELDGTTHDRAWTIEVYRNITEQFRANHPDFMGTRVILSAHRSSSVSRVKQAVQEAIEMQRKNPDIVAGFDLVGREDTGGSIWYFRDALSLPSESQLPYFFHAGETDLDGTDVDRNVLDALLFNTSRIGHGFAIVHHPVAKQLSRSRRVAVELCPISNQVLKLVSDLRNHPAAVLMSDGHPMVVSSDDPSLFGTTGLSYDFYEVFVGIGGLSANLGTLKELAINSIRYSSLSAQLQDKAMTVWQEKWNTFIAENS", "length": 501 }, "evidence": [ { "id": "HGNC:1839", "url": "https://alliancegenome.org/gene/HGNC:1839#orthology", "database": "AGR" } ], "glygen_name": 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"ZFIN:ZDB-GENE-030902-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030902-4#orthology", "database": "AGR" }, { "id": "HGNC:1839", "url": "https://alliancegenome.org/gene/HGNC:1839#orthology", "database": "AGR" }, { "id": "FB:FBgn0036752", "url": "https://alliancegenome.org/gene/FB:FBgn0036752#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VFS0-1", "protein_name": "Adenosine deaminase", "gene_name": "Adgf-C", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRRLLMFVVLLTAQLQIQAQTALSYEQARQAVLTAEEELMTGGHTHLNTEEEKVDDIFMEYKLGELAQGFRNAEQNAAALHFFKAKPLIDRSAIFRFLQKMPKGSVLHVHNTASVSSKWVVDDLSYMPGLLRCTTATGQSILSFRRTPKEHKCQSQYVLVSDERRNSLDRQVYDRNFERLINLYTPVPELEYPTITRVWDRFQGMFDGLSDALIYLPAFRAYHWQMLEELYNDNVMYTEIRTSFKTLYDASGRTFPRERTIHELYALNQKFMKLHPDFLGFKVIMAVYRGYELDHLKDIVEVFKKLHQALPHFLVGFDLVGQEDKGKPLYSLLPVLRDLPPTARLFLHGGETNWFGASTDINLLDALLMNTTRIGHGYALAKHPILLNAVKSRRIAVELSPISNQVLHLVWDLRNHPGSQFFALDVPVVICNDDPGFWNAKGLSYDFYYAIMSLAPNNAGLRLLKTLVWNSVRYSTLTEEEQTRAFKILELSWSRFIDDVLEGSVF", "length": 506 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-030902-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030902-4#orthology", "database": "AGR" }, { "id": "HGNC:1839", "url": "https://alliancegenome.org/gene/HGNC:1839#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VFS1-1", "protein_name": "Adenosine deaminase", "gene_name": "Adgf-D", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAMWFLGALVATVVLLTGSVQATDLPYETLREQIMEAERVASLGGNIWLSSDEEKANSILMNAKRAEIAEGLKTPEKYAPAMHFFQGRQYVRQSEVFRMIQKIPKGAFLHGHNTGMVTSRWIIQNLTTTNNLYTCRNVDGLLVFTYDQSGCHSEVQNVCTERINAEDRGKYERQLEKHINMHGPRPEALLPNRKKIWERFENIFTTVDRLYKYRPTYCAYHKRMLEELCEDNIIYAEIRASLSPLYDDNNRTLSTLEVANELERIVEEFKAKHHDFIGVKVIYAKRNRASEEEMLRRITTFKQLHHAKPNFVIGFDLIGQEDTGEPLNRYINQLSDLPSTANYFFHAGETNWNGRTDWNMMDAILLNTKRIGHAFALPKHPQLWSTIKKRNIAIEVNPISNQVLGFVWDLRNHPASFLIAENFPIVISSDDPGVWGAKGLSYDFYYAFMALAPADADLRFLKQLALNSIKYAVLTSDERRKINRVFQRKWQEFIANVLNPKF", "length": 502 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-030902-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030902-4#orthology", "database": "AGR" }, { "id": "HGNC:1839", "url": "https://alliancegenome.org/gene/HGNC:1839#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VVK4-1", "protein_name": "Adenosine deaminase", "gene_name": "Adgf-B", "tax_id": 7227, "organism": "Drosophila 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"" }, { "name": "cellular response to sucrose starvation", "id": "GO:0043617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043617", "evidence": [ { "database": "UniProtKB", "id": "Q9VVK5", "url": "https://www.uniprot.org/uniprotkb/Q9VVK5" } ], "pmid": "" }, { "name": "hemocyte differentiation", "id": "GO:0042386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042386", "evidence": [ { "database": "UniProtKB", "id": "Q9VVK5", "url": "https://www.uniprot.org/uniprotkb/Q9VVK5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "adenosine deaminase activity", "id": "GO:0004000", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004000", "evidence": [ { "database": "UniProtKB", "id": "Q9VVK5", "url": "https://www.uniprot.org/uniprotkb/Q9VVK5" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VVK5", "url": "https://www.uniprot.org/uniprotkb/Q9VVK5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VVK5", "url": "https://www.uniprot.org/uniprotkb/Q9VVK5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 163, "end_pos": 165, "annotation": "n_glycosylation_sequon" }, { "start_pos": 96, "end_pos": 98, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "24408", "name": "", "equation": "adenosine + H2O + H(+) = inosine + NH4(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VFS1-1", "Q9VVK5-1", "Q8IQR3-1", "Q9VVK4-1", "Q9VFS0-1" ], "evidence": [ { "id": "24408", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/24408" } ] } ], 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neuronal, 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "14503", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14503" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VVL0", "url": "https://www.uniprot.org/uniprotkb/Q9VVL0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Cln3", "url": "https://www.uniprot.org/uniprotkb/Q9VVL0", "locus": { "chromosome": "3L", "start_pos": 17809231, "end_pos": 17814119, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0036756", "url": "https://www.ensemblgenomes.org/id/FBgn0036756" } ] } } ], "crossref": [ { "id": "FB:FBgn0036756", "url": "https://alliancegenome.org/gene/FB:FBgn0036756", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0036756", "url": "https://bgee.org/?page=gene&gene_id=FBgn0036756", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0036756", "url": "https://flybase.org/reports/FBgn0036756", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "39981", "url": "https://www.ncbi.nlm.nih.gov/gene/39981", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003492", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003492", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018460", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018460", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG5582", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG5582", "database": "KEGG Pathway", "categories": [ "Enzyme and 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"Q9VVL0-1", "url": "https://www.uniprot.org/uniprotkb/Q9VVL0/entry#Q9VVL0-1", "sequence": { "sequence": "MTATKQQEAEAEHDPQVVVTPGDASRSSRQDRGLWRDLTSYWILGLCNNYGYVVMLSAAHDIIKQFNPNDESEESSSGRNCHLVSTGAILLADVLPSLFVKILMPFFPFWVNFRIALAVAFSAAGFLLVGFANAEWMALLGVIITSASSGIGETTFLAYSSRYNKNVISTWSSGTGGAGVIGSLSYASLRSLDFSPRDTMLIMLIFPAIEAFAFWLLLRRPQVDILPVTTVESTEVLISDEKPLVGFKEKLFYIKHLFKYMLPLCLVYFFEYFINQGLFELVYFEDIFLDKDSQYRWLNVDYQIGVFISRSSVNLFQLDKIWLMSIFQFVNVVYFLTEVIWWYTPSIWIVFAIVLWEGLLGGGAYVNTFYRMSKEISPERQQFAMAMVVQSDSYGIALAGFLAIPVHNAICGLPAAARSLVW", "length": 422, "header": "tr|Q9VVL0-1|Q9VVL0_DROME Isoform 1 of Battenin OS=Drosophila melanogaster OX=7227 GN=Cln3 PE=3 SV=2 CANONICAL=Q9VVL0-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 20, "start_aa": "Thr", "end_pos": 20, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr20", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VVL0", "url": "https://www.uniprot.org/uniprotkb/Q9VVL0" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VVL0", "url": "https://www.uniprot.org/uniprotkb/Q9VVL0" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVL0", "url": "https://www.uniprot.org/uniprotkb/Q9VVL0" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVL0", "url": "https://www.uniprot.org/uniprotkb/Q9VVL0" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VVL0", "url": "https://www.uniprot.org/uniprotkb/Q9VVL0" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VVL0", "url": "https://www.uniprot.org/uniprotkb/Q9VVL0" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VVL0", "url": "https://www.uniprot.org/uniprotkb/Q9VVL0" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVL0", "url": "https://www.uniprot.org/uniprotkb/Q9VVL0" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVL0", "url": "https://www.uniprot.org/uniprotkb/Q9VVL0" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VVL0", "url": "https://www.uniprot.org/uniprotkb/Q9VVL0" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VVL0", "url": "https://www.uniprot.org/uniprotkb/Q9VVL0" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], 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[ "Protein Classification" ] }, { "id": "IPR047115", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047115", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG7408", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG7408", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YTAPMCT", "url": "https://omabrowser.org/oma/group/YTAPMCT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VVM1", "url": "https://www.orthodb.org/?gene=Q9VVM1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10342", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10342", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10342:SF264", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10342:SF264", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00884", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00884", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-1663150", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1663150", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-9840310", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9840310", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001163462", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001163462", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VVM1", "url": "https://www.uniprot.org/uniprotkb/Q9VVM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VVM1-1", "url": "https://www.uniprot.org/uniprotkb/Q9VVM1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTHLDKFSSATSLLTGFVLCIALSNGIVATSDKPNIIIIMADDLGFDDVSFRGSNNFLTPNIDALAYSGVILNNLYVAPMCTPSRAALLTGKYPINTGMQHYVIVNDQPWGLPLNETTMAEIFRENGYRTSLLGKWHLGLSQRNFTPTERGFDRHLGYLGAYVDYYTQSYEQQNKGYNGHDFRDSLKSTHDHVGHYVTDLLTDAAVKEIEDHGSKNSSQPLFLLLNHLAPHAANDDDPMQAPAEEVSRFEYISNKTHRYYAAMVSRLDKSVGSVIDALARQEMLQNSIILFLSDNGGPTQGQHSTTASNYPLRGQKNSPWEGALRSSAAIWSTEFERLGSVWKQQIYIGDLLPTLAAAAGISPDPALHLDGLNLWSALKYGYESVEREIVHVIDEDVAEPHLSYTRGKWKVISGTTNQGLYDGWLGHRETSEVDPRAVEYEELVRNTSVWLQLQQVSFGERNISELRDQSRIECPDPATGVKPCLPLEGPCLFDIEADPCERSNLYAEYQNSTIFLDLWSRIQQFAKQAHPPNNKPGDPNCDPRFYHNEWTWWQDEKASSSGTIGVMKVFTLLVVFIFTSSCIN", "length": 585, "header": "tr|Q9VVM1-1|Q9VVM1_DROME Isoform 1 of Sulfatase N-terminal domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG7408 PE=1 SV=2 CANONICAL=Q9VVM1-1" }, "isoforms": [ { "isoform_ac": "Q9VVM1-1", "url": "https://www.uniprot.org/uniprotkb/Q9VVM1/entry#Q9VVM1-1", "sequence": { "sequence": "MSTHLDKFSSATSLLTGFVLCIALSNGIVATSDKPNIIIIMADDLGFDDVSFRGSNNFLTPNIDALAYSGVILNNLYVAPMCTPSRAALLTGKYPINTGMQHYVIVNDQPWGLPLNETTMAEIFRENGYRTSLLGKWHLGLSQRNFTPTERGFDRHLGYLGAYVDYYTQSYEQQNKGYNGHDFRDSLKSTHDHVGHYVTDLLTDAAVKEIEDHGSKNSSQPLFLLLNHLAPHAANDDDPMQAPAEEVSRFEYISNKTHRYYAAMVSRLDKSVGSVIDALARQEMLQNSIILFLSDNGGPTQGQHSTTASNYPLRGQKNSPWEGALRSSAAIWSTEFERLGSVWKQQIYIGDLLPTLAAAAGISPDPALHLDGLNLWSALKYGYESVEREIVHVIDEDVAEPHLSYTRGKWKVISGTTNQGLYDGWLGHRETSEVDPRAVEYEELVRNTSVWLQLQQVSFGERNISELRDQSRIECPDPATGVKPCLPLEGPCLFDIEADPCERSNLYAEYQNSTIFLDLWSRIQQFAKQAHPPNNKPGDPNCDPRFYHNEWTWWQDEKASSSGTIGVMKVFTLLVVFIFTSSCIN", "length": 585, "header": "tr|Q9VVM1-1|Q9VVM1_DROME Isoform 1 of Sulfatase N-terminal domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG7408 PE=1 SV=2 CANONICAL=Q9VVM1-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 300, "start_aa": "Thr", "end_pos": 300, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr300", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VVM1", "url": "https://www.uniprot.org/uniprotkb/Q9VVM1" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VVM1", "url": "https://www.uniprot.org/uniprotkb/Q9VVM1" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVM1", "url": "https://www.uniprot.org/uniprotkb/Q9VVM1" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVM1", "url": "https://www.uniprot.org/uniprotkb/Q9VVM1" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VVM1", "url": "https://www.uniprot.org/uniprotkb/Q9VVM1" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VVM1", "url": "https://www.uniprot.org/uniprotkb/Q9VVM1" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VVM1", "url": "https://www.uniprot.org/uniprotkb/Q9VVM1" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVM1", "url": "https://www.uniprot.org/uniprotkb/Q9VVM1" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVM1", "url": "https://www.uniprot.org/uniprotkb/Q9VVM1" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VVM1", "url": "https://www.uniprot.org/uniprotkb/Q9VVM1" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VVM1", "url": "https://www.uniprot.org/uniprotkb/Q9VVM1" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG7408", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG7408", "resource": "KEGG Pathway" }, { "id": "R-DME-1663150", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1663150", "resource": "Reactome", "description": "The activation of arylsulfatases" }, { "id": "R-DME-9840310", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9840310", "resource": "Reactome", "description": "Glycosphingolipid catabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A2R8QMU9-1", "protein_name": "Arylsulfatase I", "gene_name": "arsib", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MALLVLLILSLPACASMRTNREDFEGFRVEEKPEAAAFKPKQPPHIIFILTDDQGFNDIGYHSGEIRSPTLDKLASEGVRLENYYVQPLCTPSRSQLITGRYQIHTGLQHSIIRPRQPNCLPLDVVTLPQRLQEIGYSTHMVGKWHLGFYRKDCLPTRRGFHTYFGSLTGSVDYYTYGSCDGKSLCGFDLHEGESVAWGRAGKYSTHLYTQRVRKILATHDPTSQPLFIFLSLQAVHTPLKPPKEYIYPYRNIGNVPRRKYAAMVSIVDEAVRNITYALRKYGFYRNSVVIFSTDNGAQPLTGGSNWPLRGCKGTYWEGGIRGVGFVHSPLIRHRRRISRDLIHITDWYPTLVGLAGGNVSQHQGLDGFDVWPTISEGKESPRLEILHNIDPLNRRSRGSLKDGYGLWDTTVQAAIRVGDWKLLTGDPGNGDWVPPHVLTHFPSSWWHLERDIGEKRKSVWLFNVTGDPCERHDLAVHRPDVVRELLARLAFHNRTAIPVRYPPDDTRANPSANGGAWRPWVGEDDEEENWDGVYYKRGKNRKRKKCRLCKLQSFFKKFNLKIMSKQI", "length": 568 }, "evidence": [ { "id": "HGNC:32521", "url": "https://alliancegenome.org/gene/HGNC:32521#orthology", "database": "AGR" }, { "id": "MGI:2670959", "url": "https://alliancegenome.org/gene/MGI:2670959#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9QK47-1", "protein_name": "Arylsulfatase I", "gene_name": "si:dkey-174i8.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDVLGLGFCLLLGLIHTIEGKVVKRGRVPPHIVFVMVDDQGYNDIGYHGSEIQTPVLDQLAGEGVKLENYYVQPICSPSRSQLMTGRYQIHTGLQHSIIRARQPLCLPPDTPTLPERLQEAGYSTHMVGKWHLGFCRPECLPTSRGFQSFLGSLTGSGDHFSFQSCDGTEACGFDLHDGDRPAWELRGNYSTRLYTERVKDILRRHDHRKPLFLYVALQAVHTPLQAPGHLLRRYQALGNRPRRHYAAMVSGVDESVGEIVSELRERGYYDNSVLIYSSDNGGQPLSGGCNWPLRGGKGSYWEGGVRAVGFVHSPLLKRKGVVSHALIHISDWYPTLLSLAGYRESDSNHLDGQDVWETISSDLPCPRTEILFNIDPVSRRHGDINPKLLTLNGFGIWDTGVRAAIRAGDWKLLTGNIGDGDWFPPQTMPGGPQQWQGMEKRRDQRGKSVWLFNITADPYERADLAEARPEVVKVLLTRLSEYNRTAVSPRNPPDDPMADPQLHGGVWTPWLGQEEHRDEGGVEEPDSINRKARSKSTCRLCKLRALFKKVGSRMQRATLFL", "length": 562 }, "evidence": [ { "id": "HGNC:32521", "url": "https://alliancegenome.org/gene/HGNC:32521#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-160114-17", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-160114-17#orthology", "database": "AGR" }, { "id": "FB:FBgn0036765", "url": "https://alliancegenome.org/gene/FB:FBgn0036765#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7F4Z7-1", "protein_name": "Arylsulfatase I", "gene_name": "arsia", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAVRALLALSVLAYLGAADLTQDWTGPNQVEQPNHARPHIIFIMTDDQGFNDIGYHNTDIHTPTLDRLAAAGVKLENYYIQPICTPSRSQFITGRYQIHTGLQHSIIRSRQPSCLPFGLRTLPQRLQEAGYATHMVGKWHLGFYKRDCLPTRRGFNTYFGSLTGSVDYYTYKSCDGPKVCGFDLHDGERVAWGQGGRYSTHLYTQRVRKILAAHDPSSQPLFIFLSFQAVHTPLQSPKEYVYPYRRMGNMFRRKYAGMVSAVDEAVRNVTYALRKYGYYKNTVIFFSTDNGGQPLFGGSNWPLRGRKGTYWEGGVRGIGFVHSPLLRRRRRVSRALIHITDWYPTLMRLAGGNVSQAEGLDGFDMWDTISDGKESPRFEILHNIDPLYNAARHGSLKNGYGIWNTAVQAAVRVGDWKLLTGNPGYGDWIPPQMLGNFPESWWSLERHTEAKKSLWLFNVADDPYERFDLAERRPDVVKQLLARLSFYNRTAVPVRYPSEDPRADPSRNGGAWGPWEGDGENWEPFYIKKKKAKKQKRKFCKMKSFFRRLNIRIMSNRI", "length": 558 }, "evidence": [ { "id": "HGNC:32521", "url": "https://alliancegenome.org/gene/HGNC:32521#orthology", "database": "AGR" }, { "id": "MGI:2670959", "url": "https://alliancegenome.org/gene/MGI:2670959#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1REG3-1", "protein_name": "Arylsulfatase J isoform X1", "gene_name": "arsj", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGSLSTHGQMEKSTFLLTLLTTFSCIVSSTYGTWKSGFQSNLVNNMDKPNSQPHIIFIMVDDQGFRDVGYHGSEIKTPTLDRLAAAGVKLENYYVQPLCSPSRSQLMTGRYQIHTGLQHSIIRPTQPNCLPLENITLPQKLKNAGYSTHMVGKWHLGFYKRACMPTQRGFDTFFGSLLGSGDYYSHYKCDSPGLCGYDLHEGEEAAWEQDRGVYSTIMYTQKAVNILASHNPKRPIFLYLAFQAVHSPLQVPARYLERYKSIPNLHRRKYAAMVSCLDEAVRNLTLALKQYGYYDNMVMVYSSDNGGQPMAGGSNWPLRGSKGSYWEGGIRAVGFVHSPLLVKKGTKSKALIHITDWYPTLVMLGEGTLDENQNLDGYDVWEAISEGRPSPRLDILHNIDPIYTKAKNGSWKAGYGIWNTAVQAALRVGDWKLLTGVPGYSDWIPPQTFSTLLLANRWHNERVSWDRGKSVWLFNITADPYERVDLSRQYPHVVKKMLFKLLRYSKNAVPCRYPPKDYRSNPQYNGGVWGPWYTDDDQDEDDNLLSYDLEQMKSWKKAKRRGKFKRKI", "length": 568 }, "evidence": [ { "id": "HGNC:26286", "url": "https://alliancegenome.org/gene/HGNC:26286#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P15848-1", "protein_name": "Arylsulfatase B", "gene_name": "ARSB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGPRGAASLPRGPGPRRLLLPVVLPLLLLLLLAPPGSGAGASRPPHLVFLLADDLGWNDVGFHGSRIRTPHLDALAAGGVLLDNYYTQPLCTPSRSQLLTGRYQIRTGLQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRAIALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLAGGNNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKLARGHTNGTKPLDGFDVWKTISEGSPSPRIELLHNIDPNFVDSSPCPRNSMAPAKDDSSLPEYSAFNTSVHAAIRHGNWKLLTGYPGCGYWFPPPSQYNVSEIPSSDPPTKTLWLFDIDRDPEERHDLSREYPHIVTKLLSRLQFYHKHSVPVYFPAQDPRCDPKATGVWGPWM", "length": 533 }, "evidence": [ { "id": "HGNC:714", "url": "https://alliancegenome.org/gene/HGNC:714#orthology", "database": "AGR" }, { "id": "MGI:88075", "url": "https://alliancegenome.org/gene/MGI:88075#orthology", "database": "AGR" }, { "id": "RGD:2158", "url": "https://alliancegenome.org/gene/RGD:2158#orthology", "database": "AGR" }, { "id": "FB:FBgn0036765", "url": "https://alliancegenome.org/gene/FB:FBgn0036765#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P50429-1", "protein_name": "Arylsulfatase B", "gene_name": "Arsb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGKLSPCTGRSRPGGPGPQLPLLLLLLQLLLLLLSPARASGATQPPHVVFVLADDLGWNDLGFHGSVIRTPHLDALAAGGVVLDNYYVQPLCTPSRSQLLTGRYQIHLGLQHYLIMTCQPSCVPLDEKLLPQLLKEAGYATHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYTHEACAPIESLNGTRCALDLRDGEEPAKEYNNIYSTNIFTKRATTVIANHPPEKPLFLYLAFQSVHDPLQVPEEYMEPYGFIQDKHRRIYAGMVSLMDEAVGNVTKALKSHGLWNNTVFIFSTDNGGQTRSGGNNWPLRGRKGTLWEGGIRGTGFVASPLLKQKGVKSRELMHITDWLPTLVDLAGGSTNGTKPLDGFNMWKTISEGHPSPRVELLHNIDQDFFDGLPCPGKNMTPAKDDSFPLEHSAFNTSIHAGIRYKNWKLLTGHPGCGYWFPPPSQSNVSEIPPVGPPTKTLWLFDINQDPEERHDVSREHPHIVQNLLSRLQYYHEHSVPSHFPPLDPRCDPKSTGVWSPWM", "length": 534 }, "evidence": [ { "id": "HGNC:714", "url": "https://alliancegenome.org/gene/HGNC:714#orthology", "database": "AGR" }, { "id": "MGI:88075", "url": "https://alliancegenome.org/gene/MGI:88075#orthology", "database": "AGR" }, { "id": "RGD:2158", "url": "https://alliancegenome.org/gene/RGD:2158#orthology", "database": "AGR" }, { "id": "FB:FBgn0036765", "url": "https://alliancegenome.org/gene/FB:FBgn0036765#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P50430-1", "protein_name": "Arylsulfatase B", "gene_name": "Arsb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGELSGCTGGSRAGGPGPRLPLLLLLLLWPARASDAAPPPHVVFVLADDLGWNDLGFHGSVIRTPHLDALAAGGVVLDNYYVQPLCTPSRSQLLTGRYQIHMGLQHYLIMTCQPNCVPLDEKLLPQLLKDAGYATHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYTHEACAPIECLNGTRCALDLRDGEEPAKEYTDIYSTNIFTKRATTLIANHPPEKPLFLYLAFQSVHDPLQVPEEYMEPYDFIQDKHRRIYAGMVSLLDEAVGNVTKALKSRGLWNNTVLIFSTDNGGQTRSGGNNWPLRGRKGTLWEGGIRGAGFVASPLLKQKGVKSRELMHITDWLPTLVNLAGGSTHGTKPLDGFDVWETISEGSPSPRVELLLNIDPDFFDGLPCPGKNTTPEKNDSFPLEHSAFNTSIHAGIRYKNWKLLTGYPGCGYWFPPPSQSNISEVPSVDSPTKTLWLFDINRDPEERHDVSREHPHIVQNLLSRLQYYHEHSVPSYFPPLDPRCDPKGTGVWSPWM", "length": 528 }, "evidence": [ { "id": "HGNC:714", "url": "https://alliancegenome.org/gene/HGNC:714#orthology", "database": "AGR" }, { "id": "MGI:88075", "url": "https://alliancegenome.org/gene/MGI:88075#orthology", "database": "AGR" }, { "id": "RGD:2158", "url": "https://alliancegenome.org/gene/RGD:2158#orthology", "database": "AGR" }, { "id": "FB:FBgn0036765", "url": "https://alliancegenome.org/gene/FB:FBgn0036765#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q32KI9-1", "protein_name": "Arylsulfatase I", "gene_name": "Arsi", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHALSGFSLVSLLSLGYLSWDWAKPGLVADGPAEAGDQPSVAPPQPPHIIFILTDDQGYHDVGYHGSDIETPTLDRLAAEGVKLENYYIQPICTPSRSQLLTGRYQIHTGLQHSIIRPRQPNCLPLDQVTLPQKLQEAGYSTHMVGKWHLGFYRKECLPTRRGFDTFLGSLTGNVDYYTYDNCDGPGVCGFDLHEGESVAWGLSGQYSTMLYAQRASHILASHNPQNPLFLYVAFQAVHTPLQSPREYLYRYRTMGNVARRKYAAMVTCMDEAVRNITWALKRYGFYNNSVIIFSSDNGGQTFSGGSNWPLRGRKGTYWEGGVRGLGFVHSPLLKKKRRTSRALVHITDWYPTLVGLAGGTTSAADGLDGYDVWPAISEGRASPRTEILHNIDPLYNHARHGSLEGGFGIWNTAVQAAIRVGEWKLLTGDPGYGDWIPPQTLASFPGSWWNLERMASIRQAVWLFNISADPYEREDLAGQRPDVVRTLLARLADYNRTAIPVRYPAANPRAHPDFNGGAWGPWASEEEEEEEEEEEEGRARSFSRGRRKKKCKICKLRSFFRKLNTRLMSHRI", "length": 573 }, "evidence": [ { "id": "HGNC:32521", "url": "https://alliancegenome.org/gene/HGNC:32521#orthology", "database": "AGR" }, { "id": "MGI:2670959", "url": "https://alliancegenome.org/gene/MGI:2670959#orthology", "database": "AGR" }, { "id": "RGD:1310242", "url": "https://alliancegenome.org/gene/RGD:1310242#orthology", "database": "AGR" }, { "id": "FB:FBgn0036765", "url": "https://alliancegenome.org/gene/FB:FBgn0036765#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q32KJ7-1", "protein_name": "Arylsulfatase family, member J", "gene_name": "Arsj", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPRDSAEPLPPLFPQARVWPGKMVAMGALAGFWVLSLITYGYLSWGQDLEEEGSLRAQVEERPEAGTAVTSQPHLIFILADDQGFRDVGYHGSEIKTPTLDKLAAEGVKLENYYVQPICTPSRSQFITGKYQIHTGLQHSIIRPTQPNCLPLDNATLPQKLKEVGYSTHMVGKWHLGFYRKDCMPTKRGFDTFFGSLLGSGDYYTHYKCDSPGVCGYDLYENDNAAWDYDNGIYSTQMYTQRVQQILASHDPTKPLFLYVAYQAVHSPLQAPGRYFEHYRSIININRRRYAAMLSCLDEAIHNVTLALKRYGFYNNSIIIYSSDNGGQPTAGGSNWPLRGSKGTYWEGGIRAVGFVHSPLLKNKGTVCKELVHITDWYPTLISLAEGQIDEDIQLDGYDIWETISEGLRSPRVDILHNIDPIYTKAKNGSWAAGYGIWNTAIQSAIRVQHWKLLTGNPGYSDWVPPQAFSNLGPNRWHNERITLSTGKSIWLFNITADPYERVDLSSRYPGIVKKLLRRLSQFNKTAVPVRYPPKDPRSNPRLNGGVWGPWYKEESKKKKTNKTKAKKMQKKSKARTRKQRAARSSTKCHPRVTTG", "length": 597 }, "evidence": [ { "id": "RGD:1307640", "url": "https://alliancegenome.org/gene/RGD:1307640#orthology", "database": "AGR" }, { "id": "HGNC:26286", "url": "https://alliancegenome.org/gene/HGNC:26286#orthology", "database": "AGR" }, { "id": "MGI:2443513", "url": "https://alliancegenome.org/gene/MGI:2443513#orthology", "database": "AGR" }, { "id": "FB:FBgn0036765", "url": "https://alliancegenome.org/gene/FB:FBgn0036765#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q32KJ8-1", "protein_name": "Arylsulfatase I", "gene_name": "Arsi", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHALSGFSLVSLLSLGYLSWDWAKPGLVADGPAEAEDQPSAAPPQPPHIIFILTDDQGYHDVGYHGSDIETPTLDRLAAEGVKLENYYIQPICTPSRSQLLTGRYQIHTGLQHSIIRPRQPNCLPLDQVTLPQKLQEAGYSTHMVGKWHLGFYRKECLPTRRGFDTFLGSLTGNVDYYTYDNCDGPGVCGFDLHEGESVAWGLSGQYSTMLYAQRASHILASHSPQKPLFLYVAFQAVHTPLQSPREYLYRYRTMGNVARRKYAAMVTCMDEAVRNITWALKRYGFYNNSVIIFSSDNGGQTFSGGSNWPLRGRKGTYWEGGVRGLGFVHSPLLKKKRRTSRALVHITDWYPTLVGLAGGTTSAADGLDGYDVWPAISEGRASPRTEILHNIDPLYNHARHGSLEGGFGIWNTAVQAAIRVGEWKLLTGDPGYGDWIPPQTLASFPGSWWNLERMASIRQAVWLFNISADPYEREDLADQRPDVVRTLLARLADYNRTAIPVRYPAANPRAHPDFNGGAWGPWASDEDEEEEDEEEEGRARSFPRGRRKKKCKICKLRSFFRKLNTRLMSHRI", "length": 573 }, "evidence": [ { "id": "HGNC:32521", "url": "https://alliancegenome.org/gene/HGNC:32521#orthology", "database": "AGR" }, { "id": "MGI:2670959", "url": "https://alliancegenome.org/gene/MGI:2670959#orthology", "database": "AGR" }, { "id": "RGD:1310242", "url": "https://alliancegenome.org/gene/RGD:1310242#orthology", "database": "AGR" }, { "id": "FB:FBgn0036765", "url": "https://alliancegenome.org/gene/FB:FBgn0036765#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5FYB0-1", "protein_name": "Arylsulfatase J", "gene_name": "ARSJ", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPRGCAGHPPPPSPQACVCPGKMLAMGALAGFWILCLLTYGYLSWGQALEEEEEGALLAQAGEKLEPSTTSTSQPHLIFILADDQGFRDVGYHGSEIKTPTLDKLAAEGVKLENYYVQPICTPSRSQFITGKYQIHTGLQHSIIRPTQPNCLPLDNATLPQKLKEVGYSTHMVGKWHLGFYRKECMPTRRGFDTFFGSLLGSGDYYTHYKCDSPGMCGYDLYENDNAAWDYDNGIYSTQMYTQRVQQILASHNPTKPIFLYIAYQAVHSPLQAPGRYFEHYRSIININRRRYAAMLSCLDEAINNVTLALKTYGFYNNSIIIYSSDNGGQPTAGGSNWPLRGSKGTYWEGGIRAVGFVHSPLLKNKGTVCKELVHITDWYPTLISLAEGQIDEDIQLDGYDIWETISEGLRSPRVDILHNIDPIYTKAKNGSWAAGYGIWNTAIQSAIRVQHWKLLTGNPGYSDWVPPQSFSNLGPNRWHNERITLSTGKSVWLFNITADPYERVDLSNRYPGIVKKLLRRLSQFNKTAVPVRYPPKDPRSNPRLNGGVWGPWYKEETKKKKPSKNQAEKKQKKSKKKKKKQQKAVSGSTCHSGVTCG", "length": 599 }, "evidence": [ { "id": "RGD:1307640", "url": "https://alliancegenome.org/gene/RGD:1307640#orthology", "database": "AGR" }, { "id": "HGNC:26286", "url": "https://alliancegenome.org/gene/HGNC:26286#orthology", "database": "AGR" }, { "id": "MGI:2443513", "url": "https://alliancegenome.org/gene/MGI:2443513#orthology", "database": "AGR" }, { "id": "FB:FBgn0036765", "url": "https://alliancegenome.org/gene/FB:FBgn0036765#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5FYB1-1", "protein_name": "Arylsulfatase I", "gene_name": "ARSI", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MHTLTGFSLVSLLSFGYLSWDWAKPSFVADGPGEAGEQPSAAPPQPPHIIFILTDDQGYHDVGYHGSDIETPTLDRLAAKGVKLENYYIQPICTPSRSQLLTGRYQIHTGLQHSIIRPQQPNCLPLDQVTLPQKLQEAGYSTHMVGKWHLGFYRKECLPTRRGFDTFLGSLTGNVDYYTYDNCDGPGVCGFDLHEGENVAWGLSGQYSTMLYAQRASHILASHSPQRPLFLYVAFQAVHTPLQSPREYLYRYRTMGNVARRKYAAMVTCMDEAVRNITWALKRYGFYNNSVIIFSSDNGGQTFSGGSNWPLRGRKGTYWEGGVRGLGFVHSPLLKRKQRTSRALMHITDWYPTLVGLAGGTTSAADGLDGYDVWPAISEGRASPRTEILHNIDPLYNHAQHGSLEGGFGIWNTAVQAAIRVGEWKLLTGDPGYGDWIPPQTLATFPGSWWNLERMASVRQAVWLFNISADPYEREDLAGQRPDVVRTLLARLAEYNRTAIPVRYPAENPRAHPDFNGGAWGPWASDEEEEEEEGRARSFSRGRRKKKCKICKLRSFFRKLNTRLMSQRI", "length": 569 }, "evidence": [ { "id": "HGNC:32521", "url": "https://alliancegenome.org/gene/HGNC:32521#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-160114-17", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-160114-17#orthology", "database": "AGR" }, { "id": "MGI:2670959", "url": "https://alliancegenome.org/gene/MGI:2670959#orthology", "database": "AGR" }, { "id": "RGD:1310242", "url": "https://alliancegenome.org/gene/RGD:1310242#orthology", "database": "AGR" }, { "id": "FB:FBgn0036765", "url": "https://alliancegenome.org/gene/FB:FBgn0036765#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BM89-1", "protein_name": "Arylsulfatase J", "gene_name": "Arsj", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPRDSAEPLPPLSPQAWAWSGKFLAMGALAGFSVLSLLTYGYLCWGQDLEEEGSLKAQVDERPEAGTAGTSQPHLIFILADDQGFRDVGYHGSEIKTPTLDKLAAEGVKLENYYVQPICTPSRSQFITGKYQIHTGLQHSIIRPTQPNCLPLDNATLPQKLKEVGYSTHMVGKWHLGFYRKDCMPTKRGFDTFFGSLLGSGDYYTHYKCDSPGVCGYDLYENDNAAWDYDNGIYSTQMYTQRVQQILATHDPTKPLFLYVAYQAVHSPLQAPGRYFEHYRSIININRRRYAAMLSCLDEAIHNVTLALKRYGFYNNSIIIYSSDNGGQPTAGGSNWPLRGSKGTYWEGGIRAVGFVHSPLLKNKGTVCKELVHITDWYPTLISLAEGQIDEDIQLDGYDIWETISEGLRSPRVDILHNIDPIYTKAKNGSWAAGYGIWNTAIQSAIRVQHWKLLTGNPGYSDWVPPQAFSNLGPNRWHNERITLSTGKSIWLFNITADPYERVDLSSRYPGIVKKLLRRLSQFNKTAVPVRYPPKDPRSNPRLNGGVWGPWYKEENKKKKSNKTKAKKMQKKKSKARMRKQLAAHSSIKCHPSVATG", "length": 598 }, "evidence": [ { "id": "RGD:1307640", "url": "https://alliancegenome.org/gene/RGD:1307640#orthology", "database": "AGR" }, { "id": "HGNC:26286", "url": "https://alliancegenome.org/gene/HGNC:26286#orthology", "database": "AGR" }, { "id": "MGI:2443513", "url": "https://alliancegenome.org/gene/MGI:2443513#orthology", "database": "AGR" }, { "id": "FB:FBgn0036765", "url": "https://alliancegenome.org/gene/FB:FBgn0036765#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IQS4-1", "protein_name": "Sulfatase N-terminal domain-containing protein", "gene_name": "CG5584", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRGLSAFLLLLCLQRVKSDESAAARRPNIIIIMADDMGFDDVSFRGGREFLTPNIDALAYHGRLLDRLYAPAMCTPSRGALLSGRYPIHTGTQHFVISNEEPWALTLNATLMPEIFKEAGYSTNLVGKWHLGFSRPEYTPTRRGFDYHFGYWGAYIDYFQRRSKMPVANYSLGYDFRRNMELECRDRGVYVTDLLTAEAERLIKDHADKEQPLFLMLSHLAAHTANEDDPLQAPEEEIQKFSYIKDPNRRKYAAMISKLDQSVGRIITALSSTDQLENSIVIFYSDNGAPSVGMFSNTGSNFPLRGQKNTPWEGGVRVAGAIWSSGLQARGSIFRQPLYVADWLPTLSRAADIELDSSLKLDGIDLWPELSGSADAPHVPREILHILDDVWRLSALQMGQWKYVNGTTASGRYDSVLTYRELDDLDPRDSRYAVTVRNSATSRALSRYDLRRLTQQRISLTRRLAAVRCGDLQRSCNPLLEECLYDILSDPCEQNNLVYSERHSDVLTALRRRVQELRASASRPGNRASMPEADPTLHTCAWESFEVLKPRIVPLECDYVGVPC", "length": 564 }, "evidence": [ { "id": "RGD:1307640", "url": "https://alliancegenome.org/gene/RGD:1307640#orthology", "database": "AGR" }, { "id": "HGNC:32521", "url": "https://alliancegenome.org/gene/HGNC:32521#orthology", "database": "AGR" }, { "id": "HGNC:714", "url": "https://alliancegenome.org/gene/HGNC:714#orthology", "database": "AGR" }, { "id": "HGNC:26286", "url": "https://alliancegenome.org/gene/HGNC:26286#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-160114-17", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-160114-17#orthology", "database": "AGR" }, { "id": "MGI:2443513", "url": "https://alliancegenome.org/gene/MGI:2443513#orthology", "database": "AGR" }, { "id": "MGI:88075", "url": "https://alliancegenome.org/gene/MGI:88075#orthology", "database": "AGR" }, { "id": "MGI:2670959", "url": "https://alliancegenome.org/gene/MGI:2670959#orthology", "database": "AGR" }, { "id": "RGD:2158", "url": "https://alliancegenome.org/gene/RGD:2158#orthology", "database": "AGR" }, { "id": "RGD:1310242", "url": "https://alliancegenome.org/gene/RGD:1310242#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VVM4-1", "protein_name": "Sulfatase N-terminal domain-containing protein", "gene_name": "Dmel\\CG7402", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTSGKILVLLVVSSILSLAYGSGYSTKPNIVIILIDDMGMNDVSFHGSNQILTPNIDALAYNGILLNKHYVPNLCTPSRATLLTGKYPIHTGMQHFVIITDEPWGLPQRERLMPEIFRDAGYSTHLVGKWHLGFWRKDLTPTMRGFDHHFGYYNGYIDYYDHQVRMLDRNYSAGLDFRRDLEPCPEANGTYATEAFTSEAKRIIEQHDKSKPLFMVLSHLAVHTGNEDSPMQAPEEEVAKFPHIRDPKRRTYAGMISSLDKSVAQTIGALKDNGMLNNSIILLYSDNGAPTIGIHSNAGSNYPYRGQKESPWEGGIRSAGALWSPLLKERGYVSNQAIHAVDWLPTLAGAAGVSLPQDLPLDGINLWPMLSGNEEPKPRTMIHVLDEVFGYSSYMRDTLKYVNGSSFKGRYDQWLGELETNEDDPLGESYEQHVLASDVQSLLGNRGLTKDRIRQMRSEATETCPPIEGQNPLESHFKCEPLKAPCFFDLAKDPCERYNLAQMYPLQLQQLADELEQIRKTAIPSARVPHSDSRANPTFHNGNWEWWNNTDTQSGSGTFSINLWLAMGSIIGLVYRNLL", "length": 579 }, "evidence": [ { "id": "RGD:1307640", "url": "https://alliancegenome.org/gene/RGD:1307640#orthology", "database": "AGR" }, { "id": "HGNC:32521", "url": "https://alliancegenome.org/gene/HGNC:32521#orthology", "database": "AGR" }, { "id": "HGNC:714", "url": "https://alliancegenome.org/gene/HGNC:714#orthology", "database": "AGR" }, { "id": "HGNC:26286", "url": "https://alliancegenome.org/gene/HGNC:26286#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-160114-17", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-160114-17#orthology", "database": "AGR" }, { "id": "MGI:2443513", "url": "https://alliancegenome.org/gene/MGI:2443513#orthology", "database": "AGR" }, { "id": "MGI:88075", "url": "https://alliancegenome.org/gene/MGI:88075#orthology", "database": "AGR" }, { "id": "MGI:2670959", "url": "https://alliancegenome.org/gene/MGI:2670959#orthology", "database": "AGR" }, { "id": "RGD:2158", "url": "https://alliancegenome.org/gene/RGD:2158#orthology", "database": "AGR" }, { "id": "RGD:1310242", "url": 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Process", "total": 1, "go_terms": [ { "name": "defense response to bacterium", "id": "GO:0042742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042742", "evidence": [ { "database": "UniProtKB", "id": "Q9VVM1", "url": "https://www.uniprot.org/uniprotkb/Q9VVM1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 116, "end_pos": 118, "annotation": "n_glycosylation_sequon" }, { "start_pos": 145, "end_pos": 147, "annotation": "n_glycosylation_sequon" }, { "start_pos": 217, "end_pos": 219, "annotation": "n_glycosylation_sequon" }, { "start_pos": 255, "end_pos": 257, "annotation": "n_glycosylation_sequon" }, { "start_pos": 447, "end_pos": 449, "annotation": "n_glycosylation_sequon" }, { "start_pos": 463, "end_pos": 465, "annotation": "n_glycosylation_sequon" }, { "start_pos": 512, "end_pos": 514, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VVM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVM1" }, { "id": "PF00884", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00884" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sulfatase N-terminal", "eco_id": "ECO_0000259", "start_pos": 35, "end_pos": 362, "start_aa": "Pro", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 300 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 116, "end_pos": 118 }, { "start_pos": 145, "end_pos": 147 }, { "start_pos": 217, "end_pos": 219 }, { "start_pos": 255, "end_pos": 257 }, { "start_pos": 447, "end_pos": 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"https://www.ncbi.nlm.nih.gov/protein/NP_649038" }, "gene_names": [ { "name": "Dmel\\CG4306", "type": "recommended", "evidence": [ { "id": "Q9VVP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVP9" } ] }, { "name": "CG4306", "type": "synonym", "evidence": [ { "id": "NP_649038", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649038" }, { "id": "Q9VVP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVP9" } ] }, { "name": "Dmel\\CG4306", "type": "synonym", "evidence": [ { "id": "NP_649038", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649038" } ] }, { "name": "Dmel_CG4306", "type": "synonym", "evidence": [ { "id": "Q9VVP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVP9" } ] } ], "protein_names": [ { "name": "Gamma-glutamylcyclotransferase", "type": "recommended", "evidence": [ { "id": "Q9VVP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVP9/entry#names_and_taxonomy" } ] }, { "name": "4.3.2.9", "type": "synonym", "evidence": [ { "id": "Q9VVP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVP9/entry#names_and_taxonomy" } ] }, { "name": "CG4306-PA", "type": "synonym", "evidence": [ { "id": "NP_649038", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649038" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_649038", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649038" } ] } ], "function": [ { "annotation": "Catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides and may play a significant role in glutathione homeostasis. Induces release of cytochrome c from mitochondria with resultant induction of apoptosis.", "evidence": [ { "database": "UniProtKB", "id": "Q9VVP9", "url": "https://www.uniprot.org/uniprotkb/Q9VVP9#function" }, { "database": "UniProtKB", "id": "ARBA00059420", "url": "https://www.uniprot.org/uniprotkb/ARBA00059420#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VVP9", "url": "https://www.uniprot.org/uniprotkb/Q9VVP9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG4306", "url": "https://www.uniprot.org/uniprotkb/Q9VVP9", "locus": { "chromosome": "3L", "start_pos": 18461957, "end_pos": 18463163, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0036787", "url": "https://www.ensemblgenomes.org/id/FBgn0036787" } ] } } ], "crossref": [ { "id": "FB:FBgn0036787", "url": "https://alliancegenome.org/gene/FB:FBgn0036787", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0036787", "url": "https://bgee.org/?page=gene&gene_id=FBgn0036787", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06661", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06661", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0036787", "url": "https://flybase.org/reports/FBgn0036787", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "40017", "url": "https://www.ncbi.nlm.nih.gov/gene/40017", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017939", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017939", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036568", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036568", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG4306", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG4306", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QPEGNVH", "url": "https://omabrowser.org/oma/group/QPEGNVH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VVP9", "url": "https://www.orthodb.org/?gene=Q9VVP9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12935", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12935", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12935:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12935:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13772", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13772", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_649038", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649038", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "20505", "url": "https://www.rhea-db.org/rhea/20505", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q9VVP9", "url": "https://www.uniprot.org/uniprotkb/Q9VVP9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VVP9-1", "url": "https://www.uniprot.org/uniprotkb/Q9VVP9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNYECLIGVLSCLLVALPKGNCHSISGLNSTLNLPEIRGDQFLYFGFGSNMLIKRIHIQNPSAVRIGPALLPDYRLDFALESAGWSGSVATIVPTQGDHVWGTLWKIDLSNLPDIDSQEGVSQGIYEPRTVYVKLHGESESTPARAYLLTKQPESNLYELPKDSIPLSRQPSKTYLQCLVKGAIESSVPEDYVQRLRSIKHNGQVNSYLERKLELGGVTL", "length": 220, "header": "tr|Q9VVP9-1|Q9VVP9_DROME Isoform 1 of Gamma-glutamylcyclotransferase OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG4306 PE=1 SV=1 CANONICAL=Q9VVP9-1" }, "isoforms": [ { "isoform_ac": "Q9VVP9-1", "url": "https://www.uniprot.org/uniprotkb/Q9VVP9/entry#Q9VVP9-1", "sequence": { "sequence": "MNYECLIGVLSCLLVALPKGNCHSISGLNSTLNLPEIRGDQFLYFGFGSNMLIKRIHIQNPSAVRIGPALLPDYRLDFALESAGWSGSVATIVPTQGDHVWGTLWKIDLSNLPDIDSQEGVSQGIYEPRTVYVKLHGESESTPARAYLLTKQPESNLYELPKDSIPLSRQPSKTYLQCLVKGAIESSVPEDYVQRLRSIKHNGQVNSYLERKLELGGVTL", "length": 220, "header": "tr|Q9VVP9-1|Q9VVP9_DROME Isoform 1 of Gamma-glutamylcyclotransferase OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG4306 PE=1 SV=1 CANONICAL=Q9VVP9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 95, "start_aa": "Thr", "end_pos": 95, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr95", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "33925313", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33925313" }, { "id": "Q9VVP9", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9VVP9" } ], "filter_code": "00000000000000000000.0000000.00000001000000.1000000.0100000000.110100100001111011.10000.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_reported_with_glycan", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VVP9", "url": "https://www.uniprot.org/uniprotkb/Q9VVP9" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VVP9", "url": "https://www.uniprot.org/uniprotkb/Q9VVP9" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVP9", "url": "https://www.uniprot.org/uniprotkb/Q9VVP9" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVP9", "url": "https://www.uniprot.org/uniprotkb/Q9VVP9" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VVP9", "url": "https://www.uniprot.org/uniprotkb/Q9VVP9" } ], "reference": [ { 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Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VVP9", "url": "https://www.uniprot.org/uniprotkb/Q9VVP9" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VVP9", "url": "https://www.uniprot.org/uniprotkb/Q9VVP9" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi 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[ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VVQ5-1", "uniprot_ac": "Q9VVQ5", "uniprot_id": "Q9VVQ5_DROME", "mass": { "chemical_mass": 58895.0, "monoisotopic_mass": 58895.0 }, "refseq": { "ac": "NP_649043", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649043" }, "gene_names": [ { "name": "anon-SAGE:Wang-055", "type": "recommended", "evidence": [ { "id": "Q9VVQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVQ5" } ] }, { "name": "CG18234", "type": "synonym", "evidence": [ { "id": "NP_649043", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649043" }, { "id": "Q9VVQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVQ5" } ] }, { "name": "Dmel\\CG18234", "type": "synonym", "evidence": [ { "id": "NP_649043", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649043" }, { "id": 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"name": "anon-SAGE:Wang-055", "type": "synonym", "evidence": [ { "id": "NP_649043", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649043" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_649043", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649043" } ] } ], "function": [ { "annotation": "Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.", "evidence": [ { "database": "UniProtKB", "id": "Q9VVQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VVQ5#function" }, { "database": "UniProtKB", "id": "ARBA00002035", "url": "https://www.uniprot.org/uniprotkb/ARBA00002035#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VVQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VVQ5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "anon-SAGE:Wang-055", "url": "https://www.uniprot.org/uniprotkb/Q9VVQ5", "locus": { "chromosome": "3L", "start_pos": 18605415, "end_pos": 18603425, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0265268", "url": "https://www.ensemblgenomes.org/id/FBgn0265268" } ] } } ], "crossref": [ { "id": "FB:FBgn0265268", "url": "https://alliancegenome.org/gene/FB:FBgn0265268", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0265268", "url": "https://bgee.org/?page=gene&gene_id=FBgn0265268", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0265268", "url": "https://flybase.org/reports/FBgn0265268", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "40024", "url": "https://www.ncbi.nlm.nih.gov/gene/40024", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005123", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005123", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006620", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006620", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013547", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013547", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044862", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044862", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045054", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045054", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG18234", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG18234", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HIVLYHD", "url": "https://omabrowser.org/oma/group/HIVLYHD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VVQ5", "url": "https://www.orthodb.org/?gene=Q9VVQ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10869", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10869", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10869:SF244", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10869:SF244", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08336", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08336", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13640", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13640", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_649043", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649043", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VVQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VVQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VVQ5-1", "url": "https://www.uniprot.org/uniprotkb/Q9VVQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFIILSICLISLGPPIGLCEITNSAMSIAGMKELVDLEGFFISEMESYTAALKNKIDLMESLLQEVQSKREISRRNPEEFVAHPLNAFSLIRRLHEDWTQAELLMLNQVGLEHLQAIETGLEEAQPSDNDLNDAIGGIISLQQFYNLQPSDIANGLLMGQQYNASLTTLNCQALANACMNFNYDKYALNWFKAAVDHYNDDRDGQVYREVFDFRLPDLYINYTSVLVTKGFRKAAWKVLQDVADLDATLWLLRKDIYEVGKIDVPDPTFIITPWFDVTGCLRVGQTSQHLSCHYEKNTSEFLRIAPLKVETLSLKPHIVLYHDVIYDSEISKVKNISLPSLKSPLRILYAIDYNLKFAKIREDHQSPLSLRIKDMTGEDVQEDTDFQIDNYGICGFRNFHTDNIELQDQTAELGDRLTSIMFFMNDVAQGGALAFPNLNLTIWPQKGSALVWRNLDHRMQPNQDLLHVSCPVVVGSKWTLVKWLHERPQMFSRPCTTGRKFKSHDQSMKFRALNK", "length": 515, "header": "tr|Q9VVQ5-1|Q9VVQ5_DROME Isoform 1 of procollagen-proline 4-dioxygenase OS=Drosophila melanogaster OX=7227 GN=anon-SAGE:Wang-055 PE=3 SV=4 CANONICAL=Q9VVQ5-1" }, "isoforms": [ { "isoform_ac": "Q9VVQ5-1", "url": "https://www.uniprot.org/uniprotkb/Q9VVQ5/entry#Q9VVQ5-1", "sequence": { "sequence": "MFIILSICLISLGPPIGLCEITNSAMSIAGMKELVDLEGFFISEMESYTAALKNKIDLMESLLQEVQSKREISRRNPEEFVAHPLNAFSLIRRLHEDWTQAELLMLNQVGLEHLQAIETGLEEAQPSDNDLNDAIGGIISLQQFYNLQPSDIANGLLMGQQYNASLTTLNCQALANACMNFNYDKYALNWFKAAVDHYNDDRDGQVYREVFDFRLPDLYINYTSVLVTKGFRKAAWKVLQDVADLDATLWLLRKDIYEVGKIDVPDPTFIITPWFDVTGCLRVGQTSQHLSCHYEKNTSEFLRIAPLKVETLSLKPHIVLYHDVIYDSEISKVKNISLPSLKSPLRILYAIDYNLKFAKIREDHQSPLSLRIKDMTGEDVQEDTDFQIDNYGICGFRNFHTDNIELQDQTAELGDRLTSIMFFMNDVAQGGALAFPNLNLTIWPQKGSALVWRNLDHRMQPNQDLLHVSCPVVVGSKWTLVKWLHERPQMFSRPCTTGRKFKSHDQSMKFRALNK", "length": 515, "header": "tr|Q9VVQ5-1|Q9VVQ5_DROME Isoform 1 of procollagen-proline 4-dioxygenase OS=Drosophila melanogaster OX=7227 GN=anon-SAGE:Wang-055 PE=3 SV=4 CANONICAL=Q9VVQ5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VVQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VVQ5" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VVQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VVQ5" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VVQ5" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VVQ5" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VVQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VVQ5" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VVQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VVQ5" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VVQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VVQ5" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VVQ5" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VVQ5" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VVQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VVQ5" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VVQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VVQ5" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG18234", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG18234", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8N7T7S6-1", "protein_name": "Prolyl 4-hydroxylase subunit alpha-3", "gene_name": "p4ha3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MCSCFTLFIVLYLLNMPDESFGEMFTSMLSVNQAVSAERKLIDHLIIYIEHEAQRLEDIKRFFSRVTSLHDGIYNEPSDPIANPIAAFKLVKRLKSEWLNVVHSTEAEENIKVLREDYRRMESSLPKLEDLRGAAHGLMRLQDVYNLHVESLVRGHFQQISDPVDFYKLSVSDMLSGDDCFLVGKVAYDLEDYYHSVLWFEEAVRLFRGTEWSPENEGTLEDALDHLAFSHFKTGNISHALSLSRELLLHDPMNRRVHFNVEKYEKLLNENLPATSSGLTLKRPDGIYLRTRNAYEQLCQTKGSQPKHFENPSLFCDYFTNGSPALFLQPIRREIISLQPYVVLFHGFVTQAEAKNIRKYAMPGLRRSVVASGMNQATAEYRISKSAWLKESAHEVVGKLDQRITLVTGLNVQPPYAEYLQVVNYGIGGHYEPHFDHATSDSSPLYRLKTGNRVATIMIYLSPVQAGGSTAFIYANFSVPVVQNAALFWWNLHKNGQGNVDTLHAGCPVIVGNKWVANKWVHEYEQEFRRRCSLNPEE", "length": 538 }, "evidence": [ { "id": "MGI:2444049", "url": "https://alliancegenome.org/gene/MGI:2444049#orthology", "database": "AGR" }, { "id": "RGD:735150", "url": "https://alliancegenome.org/gene/RGD:735150#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A8DYR4-1", "protein_name": "procollagen-proline 4-dioxygenase", "gene_name": "Dmel\\CG34345", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLLRSFHYILLNWILLFLFTVCKAKKAENDVVQEVIYSNSIRALSELREIENSYMEHLNNYVSFLQQKIKTLRIFINSLTPNYLDHKVDRYKYVSNPLNSFGLLRRAHQDWPKLIAYLKDQGNIKVDIEEMNKLINRTPHANDMEEALMGMDRIEHFYDLKSSDMAQGLVAGQQLSSRMSASDCLALADYMYKRSEFRRAAEWYRIALSVFTKPKNNIAFKFYAPKRKELEKMFVISRLQEGSVENLTDCLKELSQDPNNSLVHLRPRKSPTMIEQGCQGKFPPGPQLVCRYNSTTTPFMRIAPLKEEEISRDPLIWLYHDVIYDSEIAQLTNVTREEMILGTTTNYTTPDRVNRLFHIKVTDDDGGKLDKTLVNRMADISGLDVGNTTTLARINYGLGGYFQEHSDYMDIKLYPELTEEGDRLMTFLFYMTDVPVGGTTIFPGAQLAIQPKKGSALFWYNLHNNGDPNLLTRHAVCPTIVGSRWVLVKSMLNYEQMFKKPCYK", "length": 504 }, "evidence": [ { "id": "MGI:2444049", "url": "https://alliancegenome.org/gene/MGI:2444049#orthology", "database": "AGR" }, { "id": "RGD:735150", "url": "https://alliancegenome.org/gene/RGD:735150#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q0KHY7-1", "protein_name": "procollagen-proline 4-dioxygenase", "gene_name": "Dmel\\CG15539", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPKLLISLAILYLLVLVKSHSKPKILENNYAISIYDMSKLIDYEHYLLNILQKFANALQKRVDTLEYYLEMTDYDREKNLAEDPIKHFRITRRLHSDYVNWVWFMEEQPWGTLVKDIIAIAPEMPTLKDVEEAIRGLRLIQWTYSLPTAEMAKGVLQDIHHNTSLDGMQCITIARHMVNYKDFIRAKEWLMVGLKMYEADEEIEYIYSQLGMPLVDFYELFVEIQDELGSRYLAMSELQLAIKNWPEKVSLQRALSRLKMNIRIGKEPAEKKNKSKRVYKKCCSSECRPTAKLYCLYKTTSSYFLRLAPLKMELLSLDPYMVLFHDVVSDKDIVSIRNLTKGKLARTVTVSKDGNYTEDPDRTTKGTWLVENNALIQRLSQLTQDMTNFDIHDADPFQVLNYGIGGFYGIHFDFLEDAELDNFSDRIATAVFYLSDVPQGGATIFPKLGLSVFPKKGSALLWYNLDHKGDGDNRTAHSACPTVVGSRWVMTKWINEREQIFRRPCLTSI", "length": 509 }, "evidence": [ { "id": "MGI:2444049", "url": "https://alliancegenome.org/gene/MGI:2444049#orthology", "database": "AGR" }, { "id": "RGD:735150", "url": "https://alliancegenome.org/gene/RGD:735150#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q6W3E9-1", "protein_name": "Prolyl 4-hydroxylase subunit alpha-3", "gene_name": "P4ha3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGPGARLAALLVLLKLGVGDPAAAAGREDTFSALTSVARALAPERRLLGTLRRYLRGEEARLRDLTRFYDKVLSLHEDLKIPVVNPLLVFTLIKRLPSDWRNVVHSLEATENIRAPKDGYEKVEQDLPAFEDLEGAARALMRLQDAYMLNVKGLAQGVFQRVTGSSITDLYSPRQLFSLTADDCFQVGKVAYDTGDYYHAIPWLEEAVSLFRRSYGEWKTEDEASLEDALDYLAFACYQVGNVSCALSLSREFLVYSPDNKRMARNVLKYERLLAENGHLMAAETAIQRPNVPHLQTRDTYEGLCQTLGSQPTHYQIPSLYCSYETNSSPYLLLQPARKEVIHLRPLVALYHDFVSDEEAQKIRELAEPWLQRSVVASGEKQLQVEYRISKSAWLKDTVDPVLVTLDRRIAALTGLDIQPPYAEYLQVVNYGIGGHYEPHFDHATSPSSPLYKMKSGNRAATLMIYLSSVEAGGATAFIYGNFSVPVVKNAALFWWNLHRSGEGDDDTLHAGCPVLVGDKWVANKWIHEYGQEFRRPCDTNPED", "length": 544 }, "evidence": [ { "id": "MGI:2444049", "url": "https://alliancegenome.org/gene/MGI:2444049#orthology", "database": "AGR" }, { "id": "RGD:735150", "url": "https://alliancegenome.org/gene/RGD:735150#orthology", "database": "AGR" }, { "id": "FB:FBgn0265268", "url": "https://alliancegenome.org/gene/FB:FBgn0265268#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6W3F0-1", "protein_name": "Prolyl 4-hydroxylase subunit alpha-3", "gene_name": "P4ha3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGPGARLALLALLALGGDPAAATGREDTFSALTSVARALAPERRLLGTLRRYLRGEEARLRDLTRFYDKVLSLHEDLKIPVVNPLLAFTVIKRLQSDWRNVVHSLEATENIRALKDGYEKVEQDLPAFEDLEGAARALMRLQDVYMLNVKGLARGVFQRVTGSSITDLYSPRQLFSLTADDCFQVGKVAYDTGDYYHAIPWLEEAVSLFRRAHGEWKTEDEASLEDALDYLAFACFQVGNVSCALSLSREFLVYSPDNKRMARNVLKYERLLAENGHQMAAETAIQRPNVPHLQTRDTYEGLCQTLGSQPTHYQIPSLYCSYETNSSPYLLLQPARKEVVHLRPLIALYHDFVSDEEAQKIRELAEPWLQRSVVASGEKQLQVEYRISKSAWLKDTVDPMLVTLDHRIAALTGLDIQPPYAEYLQVVNYGIGGHYEPHFDHATSPSSPLYRMKSGNRVATFMIYLSSVEAGGATAFIYGNFSVPVVKNAALFWWNLHRSGEGDGDTLHAGCPVLVGDKWVANKWIHEYGQEFRRPCSTNPED", "length": 542 }, "evidence": [ { "id": "MGI:2444049", "url": "https://alliancegenome.org/gene/MGI:2444049#orthology", "database": "AGR" }, { "id": "RGD:735150", "url": "https://alliancegenome.org/gene/RGD:735150#orthology", "database": "AGR" }, { "id": "FB:FBgn0265268", "url": "https://alliancegenome.org/gene/FB:FBgn0265268#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7Z4N8-1", "protein_name": "Prolyl 4-hydroxylase subunit alpha-3", "gene_name": "P4HA3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGPGARLAALLAVLALGTGDPERAAARGDTFSALTSVARALAPERRLLGLLRRYLRGEEARLRDLTRFYDKVLSLHEDSTTPVANPLLAFTLIKRLQSDWRNVVHSLEASENIRALKDGYEKVEQDLPAFEDLEGAARALMRLQDVYMLNVKGLARGVFQRVTGSAITDLYSPKRLFSLTGDDCFQVGKVAYDMGDYYHAIPWLEEAVSLFRGSYGEWKTEDEASLEDALDHLAFAYFRAGNVSCALSLSREFLLYSPDNKRMARNVLKYERLLAESPNHVVAEAVIQRPNIPHLQTRDTYEGLCQTLGSQPTLYQIPSLYCSYETNSNAYLLLQPIRKEVIHLEPYIALYHDFVSDSEAQKIRELAEPWLQRSVVASGEKQLQVEYRISKSAWLKDTVDPKLVTLNHRIAALTGLDVRPPYAEYLQVVNYGIGGHYEPHFDHATSPSSPLYRMKSGNRVATFMIYLSSVEAGGATAFIYANLSVPVVRNAALFWWNLHRSGEGDSDTLHAGCPVLVGDKWVANKWIHEYGQEFRRPCSSSPED", "length": 544 }, "evidence": [ { "id": "MGI:2444049", "url": "https://alliancegenome.org/gene/MGI:2444049#orthology", "database": "AGR" }, { "id": "RGD:735150", "url": "https://alliancegenome.org/gene/RGD:735150#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8IMH8-1", "protein_name": "Prolyl 4-hydroxylase N-terminal domain-containing protein", "gene_name": "CG9708", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLNLERNLLQNMRDYAEKLEEKIDLINNYVEDYNVDIEDANEDPEKYLSNPLNSFRLIRHMHQDWVGWQVYMEDLVAPEAVQKVESLLPQLPQKEAFRKAARSVHSLTQFYGYEPADLVAKDERSSSLHLSPLDCYHLGLELYEEQDYLGAAKWLQVAAHNYTLSRHRDLFNPLGAPRWQVYRDLGRTLLKLNRQCAYDAYESALRLNSQNVHLMKEAGQMELFSLRDPMEPILDLQPKPTVLEKYCRGEVPRHQGRLTCELNDWVHSFLAYAPIKFEDLQQDPFIILYPGSIYEQEIRHVENAYERCPPNDRFELKLGISGCSISDGYSPVLKRINERILDMAGVEKTWDTFYIVEYAQLAPFEPFKLFRNSTKFPKLNLMNFEDVEAKVIIFLKDVTLGGAFTMPNGDILVQPKRGNVLITFENEEHSTTICPIIEGTGLVMIKFIMKTDE", "length": 453 }, "evidence": [ { "id": "MGI:2444049", "url": "https://alliancegenome.org/gene/MGI:2444049#orthology", "database": "AGR" }, { "id": "RGD:735150", "url": "https://alliancegenome.org/gene/RGD:735150#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8IMI2-1", "protein_name": "procollagen-proline 4-dioxygenase", "gene_name": "Dmel\\CG31524", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPVLKLLFVVIFFLSLSMGQIEATQPRFARSVVNMDDLLNMEDDLVSKLEGYAEKLSYKANTIRWGIQQMREQLDKSKKEQSFDLFNRYSFIRHMQADWLMWKQYLDKPVIRDELNYKQMDNLRMPQELDLFDASEAIRRMQATYAMLSNDIAEGFLDGVQYTSKLSPIDCLAMGRHLMNQSRWTIAEQWILAGIKAQDRKGPQTEMILLRGPTKAELFRTLGKVRFERRNEEGALKAYQAALKHSPHDLEIFQEYQNLKRRVLTLSPSEPIREEPNDDIEEMELPPCCSGRCEGPRKLNRLYCVYNCVTAPFLRLAPIKTEILSVDPFVILLHDMVSHKEGALIRSSSKNQILPSETVNAANEFEIAKFRTSKSVWFDSDANEATLKLTQRLGEATGLDMKHSEPFQVINYGIGGVFESHFDTSLADEDRFVNGYIDRLATTLFYLNDVPQGGATHFPGLNITVFPKFGTVLMWYNLHTEGMLHVRTMHTGCPVIVGSKWVVSKWIDDKGQEFRRPCLRSRLDSKYLSSIEKIII", "length": 536 }, "evidence": [ { "id": "MGI:2444049", "url": "https://alliancegenome.org/gene/MGI:2444049#orthology", "database": "AGR" }, { "id": "RGD:735150", "url": "https://alliancegenome.org/gene/RGD:735150#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8IMI4-1", "protein_name": "Prolyl 4-hydroxylase N-terminal domain-containing protein", "gene_name": "CG15542", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPVVFSVLWLLQLFLLVESVAGANFARGEEQLQALLDTETQLIDGLRDYIERLERQLEEIRRETSAIEEIHSQVDSVEEYMGNPLNVFGILKRFESVWPGLEQKANATLEMVFGERLSDRQLTLPSEEDYEESLNHLLHLQSVYELDSNSLSLGVVNGFKLGSSMSWGDCLEVARKSDFPVARFWLESALEKLPSASENSTESQRERESGRVHILEATLNIEYRAGELSRALATAEELLLLLPMNQGIQKAKRKIEKAMAKKELPKGRGQKSKAKKQISKSTEQLLIEEICRGAKQQVTTGSRFNHCQLDGSSPWLLLQPSRLEPVSSDPYIVLHHDVLTPKESNELLQLIDEEEDTKGVSYQSLKLSKLAQKKLGRISRLLGLEILELDPWTGRRHGHEHITKLEHSSELKHVARLMLNLQAPGMGGAVVFPQLELAVNVPRGSLLHWRTRFAGGSSSEWDYRSGQAICPVLLGVQLSVIACQSNVLRDTLYGPRGQDSIDVGSEA", "length": 507 }, "evidence": [ { "id": "MGI:2444049", "url": "https://alliancegenome.org/gene/MGI:2444049#orthology", "database": "AGR" }, { "id": "RGD:735150", "url": "https://alliancegenome.org/gene/RGD:735150#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8IQS7-1", "protein_name": "procollagen-proline 4-dioxygenase", "gene_name": "CG13382", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRKYHSLLPVLLGFAVLNSFVGCVEDIEEKERYSSSTVGLLKLLKVEEKFTDNLLNQVDQLGEKFEALRMYLSSVGYELHRSLNEKVQYVSNPINAFSLLRRTHEDLPKWHEYFKEAIGEGNQSILVDLVKMVPNDVDMLSAMHGIQRIEKIYDLKIDDLAQGVLQGVQYNVQLTYRDLIAMGNSMYQQSDYQTAAKWYRIACKRELENPEQLFIQILGDPSEHLHRQYIKSLFKYGSTTSEPSKSIEEAFIMVQASQEELDNIMSDLNEPQNDVEVEKDLYQVKRSPSNCELGCRGLYRQKTNLVCRYKSTANTFLRLAPLKLEEISLDPFMAMYHEVLYDSEIRELKGQSMNMVNGYASQRNGTEIRDTVVRYDWWSNTSLVRERINQRIIDMTGFNFLKDEKLQIANYGLGTYFQPHFDYSSDGFETPNITTLGDRLASILFYASEVPQGGATVFPEINVTVFPQKGSMLYWFNLHDDGKPDIRSLHSVCPVLNGDRWTLTKWVPMFPQMFSFPCKS", "length": 520 }, "evidence": [ { "id": "MGI:2444049", "url": "https://alliancegenome.org/gene/MGI:2444049#orthology", "database": "AGR" }, { "id": "RGD:735150", "url": "https://alliancegenome.org/gene/RGD:735150#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9I7H5-1", "protein_name": "procollagen-proline 4-dioxygenase", "gene_name": "PH4alphaSG2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLDRHCLYIGIFQLIIWVGVANGEFYSSVDSMQDLAQVEEELLNATRSYVESQQKQLDFYRRYVEQIKREHEWATSQLKLDDYLGHPLHAFRLIKRLVRDWDSLIFEPILANNAREEFRAFVEVLSRDLGYPDQSELQGAIKGLARLQKVYNLATSDLADGIIGGLNYGSDLRWRECYEIGVQLFDLGEYQRSLEWLQVAFILLRNSPREEKDADHYLSDIREYASMANFELGNPKKAARLLSQILESQPTHSAQQTQKYLESRVPGKNVQETKPSWFSNYTRLCQGRRLPEERSGDPLRCYLDGKRHAYFTLAPLQVEPVHLDPDINVYHGMLSSKQILSIFEEADKEEMVRSAVAGSGGEGTVRDLRVSQQTWLDYKSPVMNSVGRIIQFVSGFDMAGAEHMQVANYGVGGQYEPHPDYFEVNLPKNFEGDRISTSMFYLSDVEQGGYTVFTKLNVFLPPVKGALVMWHNLHRSLHVDARTLHAGCPVIVGSKRIGNIWMHSGYQEFRRPCNLTSDSYKSLAYRD", "length": 527 }, "evidence": [ { "id": "MGI:2444049", "url": "https://alliancegenome.org/gene/MGI:2444049#orthology", "database": "AGR" }, { "id": "RGD:735150", "url": "https://alliancegenome.org/gene/RGD:735150#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VA50-1", "protein_name": "procollagen-proline 4-dioxygenase", "gene_name": "Dmel\\CG31013", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGYFIRCLLVMLFHSTLVLGHRPLEKSHSLSLVTMVPLLELEKKLIDNLENYTNALEQKLEIIRSQLLVIRAENEKGRRNAISYLSNPLNGFSIIRRLHQDWINWRKYMEQPVGIWQLKAFYSWKDELPTERDLWDACEGIARIQSTYDLKVGDFINGNINGKQYNDSMSTADILSVGAYLFMKNRPSDAIQWLQEVPQRLQEELLIQPRHLPIKEVDALRLLAEAQIKDQNYSEALPLLHNCLKLQPHDARVLRLWKKTTDFIENQPDQSPTENKKRNVPIANAFKLSCNGPLESSTRLHCFYNFTTTPFLRLAPLKTEQIGLDPYVVLYHEVLSAREISMLIGKAAQNMKNTKIHKERAVPKKNRGRTAKGFWLKKESNELTKRITRRIMDMTGFDLADSEGFQVINYGIGGHYFLHMDYFDFASSNHTDTRSRYSIDLGDRIATVLFYLTDVEQGGATVFGDVGYYVSPQAGTAIFWYNLDTDGNGDPRTRHAACPVIVGSKWVMTEWIREKRQIFIRPCLPKAKGTSTKS", "length": 534 }, "evidence": [ { "id": "MGI:2444049", "url": "https://alliancegenome.org/gene/MGI:2444049#orthology", "database": "AGR" }, { "id": "RGD:735150", "url": "https://alliancegenome.org/gene/RGD:735150#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VA52-1", "protein_name": "procollagen-proline 4-dioxygenase", "gene_name": "CG9708", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSSVVLFAVSFILVLSWIAEGYRDRQNYVISVEEKMDLLEKDRELIIVLDSYATELNEKIIMLKRIVKEFKQPLEKAKNREEEYLSNPIDSLSLMRQMHEDWEKVEKLLKKPVGQEKIALVEKMREDLPVENDLMEANQAMFRILHTYDLEPKDVSAGWIDGVQYGGKMSASDCFTMGTFSFMAGSYQIASKWLSAAKDLLVDQPRKYHEVMGITKADVTLLLARSLIASGNVSIATDMLMRDFMFGEAGSALTVHFLRNKPKPSINLESWESDESFNQLCRSSSRRQMGESKPSRLHCRYNTITTPFLKLAPFRMEELSLDPYVIFYHNVLSDAEIEKLKPMGKPFLERAKVFRVEKGSDEIDPSRSADGAWLPHQNIDPDDLEVLNRIGRRIEDMTGLNTRSGSKMQFLKYGFGGHFVPHYDYFNSKTFSLETVGDRIATVLFYLNNVDHGGATVFPKLNLAVPTQKGSALFWHNIDRKSYDYDTRTFHGACPLISGTKLVMTRWIYELDQMFLIPAVLPPRSRNFSKSLPNPF", "length": 536 }, "evidence": [ { "id": "MGI:2444049", "url": "https://alliancegenome.org/gene/MGI:2444049#orthology", "database": "AGR" }, { "id": "RGD:735150", "url": "https://alliancegenome.org/gene/RGD:735150#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VA60-1", "protein_name": "procollagen-proline 4-dioxygenase", "gene_name": "Dmel\\CG9698", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MIFPVFSVLFLLFHQAIPSVSGVEFFSSIHEMTKVFGYEQKMVLHMQKFLSDNQDKLDFLKARLREFENERNEAREWGPSYFESPINKYLLNKRLTVDWQRVENLMATSTGEKPLTRLRKFRNRETMPDKKELEGAIDGLLRLQYVYRLKAKDLARGILDGVDYGTQLNSEHCVDIARLALRDQHPRLAHSWLIEANDRLTGGEKEEQLKPQILALLVQAKKELEDFRGLNDTYQELIGIQSASEEHAKNYETFLNALSEKALLNESKPILEHAPIPEEGEPVGEFQAYSLTCSGHWRLTPKEQRHLRCGYVTETHPFLWIAPLKAEELFQDPLLVLYHDVIYQSEIDVIRKLTENRLMRATITSHNESVVSNVRTSQFTFIPVTAHKVLSTIDQRVADMTNLNMKYAEDHQFANYGIGGHYGQHMDWFYQTTFDAGLVSSPEMGNRIATVLFYLSDVAQGGGTAFPQLRTLLKPKKYAAAFWHNLHASGVGDVRTQHGACPIIAGSKWVQNRWIRENDQSDRRPCELWDDSLATYAQILELNKQNE", "length": 547 }, "evidence": [ { "id": "MGI:2444049", "url": "https://alliancegenome.org/gene/MGI:2444049#orthology", "database": "AGR" }, { "id": "RGD:735150", "url": "https://alliancegenome.org/gene/RGD:735150#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VA61-1", "protein_name": "procollagen-proline 4-dioxygenase", "gene_name": "PH4alphaNE2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLFWRLVLLGMLYLSLSFGQLRENNAQQRFARSVVNMDDMLNLEDDLVSNVEKLAEALARKAKTIKWGVFKMMKRRQEYKSSMEIFANPIDTFSLIRHMQSNWLMWLLYLETPVGQEELFFVDSRMPLLPKYFDFIDAAEGIRKMQATYQMFSSDIAKGLLDGVQYNSSLKPIDCLAIGLHLMNNSRWYAAEQWISASIEAYDQKSSQTDMELLRGPKLADLCRILGQVQMKQRNHEGALQAYQVALKLSPHDPEIYEEYRILEKRDLTLSDIEPIEQDKDNSHERLVLPPCCSGRCQVPRNLSNLYCVYNHVTSPFLQLAPIKTEILSIDPFVVLLHDMISQKESTLIRTSSKEHMLPSATTDPDASDDETQVDTYRTSKSVWYSSDFNDTTKKITERLGDATGLDMNSTEFYQVINYGLGGFFETHLDMLLSEKNRFNGTSDRIATTLFYLNEVRQGGGTYFPRLNLTVFPQPGSALFWYNLDTKGNDHMGSLHTGCPVIVGSKWVMSKWINDMGQEFTRPCVESSLSSNEVLSAERLII", "length": 542 }, "evidence": [ { "id": "MGI:2444049", "url": "https://alliancegenome.org/gene/MGI:2444049#orthology", "database": "AGR" }, { "id": "RGD:735150", "url": "https://alliancegenome.org/gene/RGD:735150#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VA63-1", "protein_name": "procollagen-proline 4-dioxygenase", "gene_name": "PH4alphaSG1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFRLSIILSLLCVFPVNGDYYSAISELERLLDVEAFIVEKFDEYLERAQQEQENLKRFLDQIDEQQNDRGDLEEYFGNPINAFITIKRLVHDWKFNVFDPVFDSSNFETYKNNLSDSLEKINFKGPTQEDLHGATRALLRLQNMYQLNTDHLASGVLHPGEKNALGTSLSASDCFELGKNLCEIKEYSYGSEWLLEARKRLHGKPLGFISPNVSDVEILEHLSSAFNGLGNLKLAYKLNNEILDKKPDHEEALKNKILYEGQLARERSFAPRKQVELPQIAEKEQKESYKLYTQVCRGELHQSPREQRNLRCWLYHQGVPYYRLSPFKIEQLNVDPYVAYVHEVLWDSEIDTIMEHGKGNMERSKVGQSENSTTSEVRISRNTWLWYDANPWLSKIKQRLEDVTGLSTESAEPLQLVNYGIGGQYEPHFDFVEDDGQSVFSWKGNRLLTALFYLNDVALGGATAFPFLRLAVPPVKGSLLIWYNLHSSTHKDFRTKHAGCPVLQGSKWICNEWFHVGAQEFRRPCGLSSDEGKFLHLKDI", "length": 540 }, "evidence": [ { "id": "MGI:2444049", "url": "https://alliancegenome.org/gene/MGI:2444049#orthology", "database": "AGR" }, { "id": "RGD:735150", "url": "https://alliancegenome.org/gene/RGD:735150#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VA64-1", "protein_name": "procollagen-proline 4-dioxygenase", "gene_name": "PH4alphaNE1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRGLVLLVGLIFLLAQGSLASDYFSSITGLEDLLHTEQYLTRELRSKVNAIQTALQQLESELSSIEKEHTMAASDTENYLTNPVNVYRLMKRLHTDWSLMEGRVQLMAEEMNFNATREYGLSYPSQEDVEGAALALVRLQSTYKLDVAQVAQGILNGVKYGSDMSWQDCFELGQQLFEMEDYNNTKVWLRESMERLRRQTSHAPSHLAPTSGPDTVTLNKMEATAKSLFQLGDFDTAFELSQRVLQFDPKRIRNWHLGDKGTAPPEDIDDVYLPKHSDSYSLSQEFAKYEKVCRGEVHPIVRQELRCRYSRGNHPYRFLAPLKLEEHSLDPYVATFHDILSPGKISQLREMAVPRMHRSTVNPLPGGQLKKSAFRVSKNAWLAYESHPTMVGMLRDLKDATGLDTTFCEQLQVANYGVGGHYEPHWDFFRDPNHYPAEEGNRIATAIFYLSEVEQGGATAFPFLDIAVKPQLGNVLFWYNLHRSLDKDYRTKHAGCPVLKGSKWIGNVWIHEVTQTFARPCDVFRDHEVSLEYEIIK", "length": 537 }, "evidence": [ { "id": "MGI:2444049", "url": "https://alliancegenome.org/gene/MGI:2444049#orthology", "database": "AGR" }, { "id": "RGD:735150", "url": "https://alliancegenome.org/gene/RGD:735150#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VA65-1", "protein_name": "procollagen-proline 4-dioxygenase", "gene_name": "PH4alphaMP", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLLAKCVLFLVLQVLSCHGEFFSSTSGLAKLFETEVVLLAELQNYVNEINQHAEALQSEIDAIRVEHLNAADGIDDYLNNPVNAFRLIKRLHSDWETFEGSVTADSSRSNYLDTMASLKENLSFPSQDDFVGSAIALTRLQQTYQLDVAELASGILNGVKYGTAMSWQDCFVLGQHLYALRDYNHTVPWLQQSMQLLGEQSYGSESASLDFMEAVVEYHREMGAHESALSLVNHVLSIEPDQRSHLLEARQQLEELITDGDKNGLLHLTARRPGDYHESREFRMYEQVCRGELAPLPSKQRNLRCRLRKSRLGYAPFKLEELHLDPLVVQLHQVIGSKDSDSLQKTARPRIKRSTVYSLGGNGGSTAAAFRTSQGASFNYSRNAATKLLSRHVGDFSGLNMDYAEDLQVANYGIGGHYEPHWDSFPENHIYQEGDLHGNRMATGIYYLADVEAGGGTAFPFLPLLVTPERGSLLFWYNLHPSGDQDFRTKHAACPVLQGSKWIANVWIRERNQDNVRPCDLERGQEISLHYRDFD", "length": 535 }, "evidence": [ { "id": "MGI:2444049", "url": "https://alliancegenome.org/gene/MGI:2444049#orthology", "database": "AGR" }, { "id": "RGD:735150", "url": "https://alliancegenome.org/gene/RGD:735150#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VHU7-1", "protein_name": "procollagen-proline 4-dioxygenase", "gene_name": "CG7553", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MYILKNLTLIGFLSACFINCQGFVKSNPKKSYAASTMELMKLLEVEDELVDNLKGYVKTLKMKFNLMERSLIDMSRENMEMKSDYESYLGNPLNSFRLIHRLHTSWRKWYQYAIKVENNALGHIENARLMRKMLPTSSDLQQACRGIHDLMSFYDLKPEELAAGNLAGYSQPGTGLTAYDCLALGEFSVQKREDDLAEAWYNLSLIRFENKFDKYRVHKAWGLLLAKNKQLTDAFYHFENKPEGIIASNEVIHFKEELSTKQNCAVVVQKPSRLHCRYNTTTTPFTRIAPLKMEELGLDPYMVVFHDVIYDTEIDGMLNSSNFGLSLTDSGQKSEVRTSKDSYIVDAKTLNERVTDMTGFSMEMSDPFSLINYGLGGHYMLHYDFHEYTNTTRPKQGDRIATVLFYLGEVDSGGATIFPMINITVTPKKGSAVFWYNLHNSGAMNLKSLHSACPVISGSKYVLTKWINELPQMFVTPCMKDSNLHPPQKE", "length": 490 }, "evidence": [ { "id": "MGI:2444049", "url": "https://alliancegenome.org/gene/MGI:2444049#orthology", "database": "AGR" }, { "id": "RGD:735150", "url": "https://alliancegenome.org/gene/RGD:735150#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VVQ6-1", "protein_name": "procollagen-proline 4-dioxygenase", "gene_name": "Dmel\\CG18233", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLNVVRAAAVLILVQSIHSTDPNDFLNRKYYSSSVLGLVKLLKMEQEFMVNFSIYANILQEKVDNLNIFLDALKRPNHKTHNEREKFVSNPLNAFGLIRRLNQDWPKLQNYTQKPLGLEQLTAMQDIVSAAPESFDMNEKLKAMHRIETTYDLQPKDIAKGLLQRTEFNYRLLFRDCLALAYHKFEIGEFKRSLLWFQEALKLSTDGSLEIMNRLKEIELKGFATAVAKRSIYLSNQGLTNETIDDMANSQLQDAKLMDLEQLISSELKQWINDDSTTPPTDHNLGCRGLFPKKSNLVCRYNSSTNAFLKLAPLKMEEISRDPYIVMFHEVISDKDIEEMKGEITEMENGWTSLGDPKEIVSRVYWIRKESSFSKRINQRISDMTGFKLEEFPAIQLANFGVGGYFKPHYDFYTDRLKEVDVNNTLGDRIGSIIFYAGEVSQGGQTVFPDLKVAVEPKKGNALFWFNAFDDSTPDPRSLHSVCPVLVGSRWTITKWLHYAPQLFVKPCSPRVHLE", "length": 515 }, "evidence": [ { "id": "MGI:2444049", "url": "https://alliancegenome.org/gene/MGI:2444049#orthology", "database": "AGR" }, { "id": "RGD:735150", "url": "https://alliancegenome.org/gene/RGD:735150#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VVQ7-1", "protein_name": "Prolyl 4-hydroxylase alpha subunit domain-containing protein", "gene_name": "Dmel\\CG18231", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGDNSGESEYVENNSVYSSITRLLKLLEMEEIFITNIKAYTNKLAEKVKNLQAYIDSVDYEFQQSFEDREKYVGNPINAFSLVRRTHQDLPKWHNYSQQIVGMEELFALEEIIAKVPDKKDMAYSLGEMHRIEQIYDLEAIELARGRIQGKQYDFRPSIRDCVALGEHKFKREDYQRASMWFRVAIKHEPEGNAEIINSILGDPKVNLYTLYAKSMLIFGMIKSNPSMTIAEAKKISYEALNKASLADIKSLLNELLSQTDDEIVYEMNVNKTKPSDYEIGCRGQFLRRRNHVCTYNFTITEFLKLAPLKQEVLNWDPYIVIYHDVLNDDEIDKLKNHLNDTDAVEVNPIEKRIFQRINELTRLSFEHSDQQIVSKNGPRTHKHKKEYLKGTLLFFLNNVELGGAMVFPKLKISVFPQKGSCLFWHNTLDPRSEPLECPVLQGNKRVITQKGAYNGRPMQYKKAKSNQKF", "length": 470 }, "evidence": [ { "id": "MGI:2444049", "url": "https://alliancegenome.org/gene/MGI:2444049#orthology", "database": "AGR" }, { "id": "RGD:735150", "url": "https://alliancegenome.org/gene/RGD:735150#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VVQ9-1", "protein_name": "procollagen-proline 4-dioxygenase", "gene_name": "Dmel\\CG32199", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MIYSTSVMSMMKLLEMEESLKTNLDIYVQEMQSKLDLIKLYQDSLKRVTLTTLEEKEEYVSNPLNAFPMLRRLNQDWPKWLRYIKLAIASKKIKEMEVQLKSAPIDDDLKVALKGMTRIEKFHNLHAEDLTKGVLMGKKLNSHLTAPDCVALGDYYYNQTQFSGSTHWYRMALRVHTHPRGMIYAKVLGLKRKRIYKKYAKALLKESLNSDKSKPTPTEKSEWNRLAKEVTREDNYDNVKKLIDEYLSGDEKIFQEVAARLKRKPTKLERGCRGEWPKKSSPELICRYNRDTSAFLKLAPLKLEFLSVQPMILLYHDVLYENEFKSMRDIAMYNGSMIDGWTYVDFDKKGNPKQQDRVVKMIAFQGTTAPFTLSINRRMADMSGLEMRDNMVLYLTNYGLGGHFGKHVDYVELAKRPPDFFADFGGDRIATALIYASDIPLGGTTVFTKLKIAVQPKKGSALIWFNLNHAGEPDPLTEHSVCPVVLGSRWIISKWIHERQQVFKKPCLA", "length": 509 }, "evidence": [ { "id": "MGI:2444049", "url": "https://alliancegenome.org/gene/MGI:2444049#orthology", "database": "AGR" }, { "id": "RGD:735150", "url": "https://alliancegenome.org/gene/RGD:735150#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "Q9VVQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VVQ5" } ], "pmid": "" }, { "name": "L-ascorbic acid binding", "id": "GO:0031418", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031418", "evidence": [ { "database": "UniProtKB", "id": "Q9VVQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VVQ5" } ], "pmid": "" }, { "name": "procollagen-proline 4-dioxygenase activity", "id": "GO:0004656", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004656", "evidence": [ { "database": "UniProtKB", "id": "Q9VVQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VVQ5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q9VVQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VVQ5" } ], "pmid": "" }, { "name": "endoplasmic reticulum lumen", "id": "GO:0005788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005788", "evidence": [ { "database": "UniProtKB", "id": "Q9VVQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VVQ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 163, "end_pos": 165, "annotation": "n_glycosylation_sequon" }, { "start_pos": 221, "end_pos": 223, "annotation": "n_glycosylation_sequon" }, { "start_pos": 297, "end_pos": 299, "annotation": "n_glycosylation_sequon" }, { "start_pos": 335, "end_pos": 337, "annotation": "n_glycosylation_sequon" }, { "start_pos": 439, "end_pos": 441, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VVQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVQ5" }, { "id": "PS51471", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51471" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fe2OG dioxygenase", "eco_id": "ECO_0000259", "start_pos": 376, "end_pos": 486, "start_aa": "Thr", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.14.11.2", "ec_name": "L-prolyl-[collagen] + 2-oxoglutarate + O2 = trans-4-hydroxy-L-prolyl-[collagen] + succinate + CO2.", "evidence": [ { "id": "1.14.11.2", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.2" }, { "id": "1.14.11.2", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.14.11.2" } ] } ], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 163, "end_pos": 165 }, { "start_pos": 221, "end_pos": 223 }, { "start_pos": 297, "end_pos": 299 }, { "start_pos": 335, "end_pos": 337 }, { "start_pos": 439, "end_pos": 441 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VVV1-1", "uniprot_ac": "Q9VVV1", "uniprot_id": "Q9VVV1_DROME", "mass": { "chemical_mass": 46968.0, "monoisotopic_mass": 46968.0 }, "refseq": { "ac": "NP_001262027", "name": "uncharacterized protein, isoform B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262027" }, "gene_names": [ { "name": "CT12789", "type": "recommended", "evidence": [ { "id": "Q9VVV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVV1" } ] }, { "name": "CG3819", "type": "synonym", "evidence": [ { "id": "NP_001262027", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262027" }, { "id": "Q9VVV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVV1" } ] }, { "name": "CT12789", "type": "synonym", "evidence": [ { "id": "NP_001262027", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262027" } ] }, { "name": "Dmel\\CG3819", "type": "synonym", "evidence": [ { "id": "NP_001262027", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262027" }, { "id": "Q9VVV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVV1" } ] }, { "name": "Dmel_CG3819", "type": "synonym", "evidence": [ { "id": "Q9VVV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVV1" } ] } ], "protein_names": [ { "name": "DNA/RNA non-specific endonuclease/pyrophosphatase/phosphodiesterase domain-containing protein", "type": "recommended", "evidence": [ { "id": "Q9VVV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVV1/entry#names_and_taxonomy" } ] }, { "name": "CG3819-PB", "type": "synonym", "evidence": [ { "id": "NP_001262027", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262027" } ] }, { "name": "uncharacterized protein, isoform B", "type": "synonym", "evidence": [ { "id": "NP_001262027", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262027" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VVV1", "url": "https://www.uniprot.org/uniprotkb/Q9VVV1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "CT12789", "url": "https://www.uniprot.org/uniprotkb/Q9VVV1", "locus": { "chromosome": "3L", "start_pos": 18920430, "end_pos": 18922108, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0036833", "url": "https://www.ensemblgenomes.org/id/FBgn0036833" } ] } } ], "crossref": [ { "id": "FB:FBgn0036833", "url": "https://alliancegenome.org/gene/FB:FBgn0036833", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0036833", "url": "https://bgee.org/?page=gene&gene_id=FBgn0036833", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00091", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00091", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0036833", "url": "https://flybase.org/reports/FBgn0036833", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "40069", "url": "https://www.ncbi.nlm.nih.gov/gene/40069", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001604", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001604", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040255", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040255", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044925", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044925", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044929", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044929", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG3819", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3819", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KCSSWPA", "url": "https://omabrowser.org/oma/group/KCSSWPA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VVV1", "url": "https://www.orthodb.org/?gene=Q9VVV1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13966", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13966", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13966:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13966:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01223", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01223", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001262027", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262027", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VVV1", "url": "https://www.uniprot.org/uniprotkb/Q9VVV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VVV1-1", "url": "https://www.uniprot.org/uniprotkb/Q9VVV1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKCLVLIAFSGLFLASAQARILPAEDLPWELPEVPVAVNEIEPRAAGCSIKIRSSELKDPQPLLIKSDTSEIVGFSDTGYVDVDKDKTIEFHCTSSLASPLSGKSVTAKCVGGTTFKIDDKEHDLSAIKCTSWPVFVGKKSGSSCNGGTTLIKVGFELSGSRFATQYEVCFNEDEEVTRYVYHRLEPGNNYYATGVDRITFGAGGYFAGKNVDKLYTQAVQKETIDKELDMDSSRFFDSAKNIFLARGHMGAKADFVFAPEQRATFLFINAAPQWQTFNAGNWARVEDGVRAWVAKENKHVECWTGVWGVTTLPNKNGEQRQLYLSHDNNGNGLIPVPKLYFRVVIEPSTKKGIVLIGVNNPHLSLEEIKRDYILCTDVSDRINWISWKKTDITAGYSYACEVPEFRKKVTHLPEFSVSGLLV", "length": 423, "header": "tr|Q9VVV1-1|Q9VVV1_DROME Isoform 1 of DNA/RNA non-specific endonuclease/pyrophosphatase/phosphodiesterase domain-containing protein OS=Drosophila melanogaster OX=7227 GN=CT12789 PE=3 SV=1 CANONICAL=Q9VVV1-1" }, "isoforms": [ { "isoform_ac": "Q9VVV1-1", "url": "https://www.uniprot.org/uniprotkb/Q9VVV1/entry#Q9VVV1-1", "sequence": { "sequence": "MKCLVLIAFSGLFLASAQARILPAEDLPWELPEVPVAVNEIEPRAAGCSIKIRSSELKDPQPLLIKSDTSEIVGFSDTGYVDVDKDKTIEFHCTSSLASPLSGKSVTAKCVGGTTFKIDDKEHDLSAIKCTSWPVFVGKKSGSSCNGGTTLIKVGFELSGSRFATQYEVCFNEDEEVTRYVYHRLEPGNNYYATGVDRITFGAGGYFAGKNVDKLYTQAVQKETIDKELDMDSSRFFDSAKNIFLARGHMGAKADFVFAPEQRATFLFINAAPQWQTFNAGNWARVEDGVRAWVAKENKHVECWTGVWGVTTLPNKNGEQRQLYLSHDNNGNGLIPVPKLYFRVVIEPSTKKGIVLIGVNNPHLSLEEIKRDYILCTDVSDRINWISWKKTDITAGYSYACEVPEFRKKVTHLPEFSVSGLLV", "length": 423, "header": "tr|Q9VVV1-1|Q9VVV1_DROME Isoform 1 of DNA/RNA non-specific endonuclease/pyrophosphatase/phosphodiesterase domain-containing protein OS=Drosophila melanogaster OX=7227 GN=CT12789 PE=3 SV=1 CANONICAL=Q9VVV1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VVV1", "url": "https://www.uniprot.org/uniprotkb/Q9VVV1" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VVV1", "url": "https://www.uniprot.org/uniprotkb/Q9VVV1" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVV1", "url": "https://www.uniprot.org/uniprotkb/Q9VVV1" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVV1", "url": "https://www.uniprot.org/uniprotkb/Q9VVV1" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VVV1", "url": "https://www.uniprot.org/uniprotkb/Q9VVV1" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VVV1", "url": "https://www.uniprot.org/uniprotkb/Q9VVV1" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VVV1", "url": "https://www.uniprot.org/uniprotkb/Q9VVV1" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVV1", "url": "https://www.uniprot.org/uniprotkb/Q9VVV1" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVV1", "url": "https://www.uniprot.org/uniprotkb/Q9VVV1" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VVV1", "url": "https://www.uniprot.org/uniprotkb/Q9VVV1" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VVV1", "url": "https://www.uniprot.org/uniprotkb/Q9VVV1" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG3819", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3819", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZTW9-1", "protein_name": "Nuclease EXOG, mitochondrial", "gene_name": "Exog", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAKGFASRLRDSRRFLNGFLAGAVVGAAGAGLTALQFLQRRDAGSARPARQPHESVEKVVLEQFGFPLTGTETRRYTNHALSYDQAKRVPRWVLEHISKDKIIGDADRKHCKFKPDPTVPSAFSALNEDYIGSGWSRGHMAPAGNNKFSSEAMAETFYLSNIVPQNFENNSGYWNRIEMYCRELTERFEDVWIVSGPLTLPHTRNDGTKTVSYQVIGEDNVAVPSHLYKVILARRSPESTEPLALGAFVVPNKAIGFQSQLSEFQVSLHDLEKMSGLVFFPHLDRTRDIRNICSVDTCKLLGFQEFTLYLSTRKIDGARSVARLEKVLEALKSSGVEPDDYFLSRYGKKLEELKAKEQKDAQLEKQS", "length": 368 }, "evidence": [ { "id": "HGNC:3347", "url": "https://alliancegenome.org/gene/HGNC:3347#orthology", "database": "AGR" }, { "id": "MGI:2143333", "url": "https://alliancegenome.org/gene/MGI:2143333#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P08466-1", "protein_name": "Mitochondrial nuclease", "gene_name": "NUC1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MCSRILLSGLVGLGAGTGLTYLLLNKHSPTQIIETPYPPTQKPNSNIQSHSFNVDPSGFFKYGFPGPIHDLQNREEFISCYNRQTQNPYWVLEHITPESLAARNADRKNSFFKEDEVIPEKFRGKLRDYFRSGYDRGHQAPAADAKFSQQAMDDTFYLSNMCPQVGEGFNRDYWAHLEYFCRGLTKKYKSVRIVTGPLYLPKKDPIDNKFRVNYEVIGNPPSIAVPTHFFKLIVAEAPTANPAREDIAVAAFVLPNEPISNETKLTDFEVPIDALERSTGLELLQKVPPSKKKALCKEVNCQIVVRDFSNAAIKQSKDVKLLPPPKKRN", "length": 329 }, "evidence": [ { "id": "HGNC:3347", "url": "https://alliancegenome.org/gene/HGNC:3347#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q7KRX0-1", "protein_name": "Endonuclease", "gene_name": "Dmel\\CG33346", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKMHELRYLIITLSLFLTVGNVKSFCQITQAETWTDRLFVHIVNNRYELLLTDQLQPNQQISLLCDGNAQVFTSTCRNNGQFSPPLPRTNCSKAIPPSVVPTSSNICPHTMYLVGFKYGNTFMELYRSCYDARTMKAYFSINTVYPTNLKSDRPPTVFDKDGIITPADEATFQMNSIYNRFEYLFGSGQTYVPSSRSLSFDRGHLTPVADYSFPKILRQTNKYLNVVPQYYNINRSNWKIVENWVRGQKDVLNVCTGALGVLDLLNRSQKSVSIYLAPNKNPVPRWTYKIIRSLTTGIKYVILTSNNGWETQQPNPASVCKVTACPRTLNPTGTGYTFCCDPIDFIRRNVPNLAGVCWDNTENV", "length": 364 }, "evidence": [ { "id": "HGNC:3347", "url": "https://alliancegenome.org/gene/HGNC:3347#orthology", "database": "AGR" }, { "id": "MGI:2143333", "url": "https://alliancegenome.org/gene/MGI:2143333#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8C163-1", "protein_name": "Nuclease EXOG, mitochondrial", "gene_name": "Exog", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAKSFASRLRDSRRFLNGFLAGAVVGAAGAGLTALQFFRRPDAESAKLARQPHESAEEAVLEQFGFPLAGTETRRYTNHALSYDQAKRVPRWVLEHISKDKIIGDADRKHCKFKPDPSVPSAFSALNEDYIGSGWSRGHMAPAGNNKFSSEAMAETFYLSNIVPQNFDNNSGYWNRIEMYCRELTERFEDVWIVSGPLTLPHTRNDGTKTVSYQVIGEDNVAVPSHLYKVILARRSPESTEPLALGAFVVPNKAIGFQSQLSEFQVSLHDLEKMSGLVFFPRLDRSRDIRNICSVDTCKLLGFQEFTLYLSTRKIDGARSVARLEKVLEALKSSGVEPDDYFLSRYEKKLEELKAKEQKDAQLEKQS", "length": 368 }, "evidence": [ { "id": "HGNC:3347", "url": "https://alliancegenome.org/gene/HGNC:3347#orthology", "database": "AGR" }, { "id": "MGI:2143333", "url": "https://alliancegenome.org/gene/MGI:2143333#orthology", "database": "AGR" }, { "id": "FB:FBgn0036833", "url": "https://alliancegenome.org/gene/FB:FBgn0036833#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VAU2-1", "protein_name": "3.-.-.-", "gene_name": "Sid", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPDLKYMLTILSLYFFVGSVQANCLIDLAHLNANYVYLSQNNGVYDIQRSDIVEIHQTLYLLCNGGLHRTTFLCRYDSVFSPALSSAACAPPDPVVVKVPDTSCSIPSATFAVGFSFNGRFMELYRNCFDGYSLAFQHSIYKAYRYVNTVPRPNPTWQSDQLSGGFDNAYEGRATQACLLTNLGAVQPQCKFDRGHMTPASAFISTELKKSTFRYLNAIPQYRGVNRGKWKAVETWVNNMVRGLYDNPIINNVQIPRTYDVLKVCIGALGVHRLRHNTNNNMIPIYLLDNNKIPVPEWMYKIVSHLSGDKWVMLTYNDVSLPNQQALNQICHVIPCHPGLNLNTKDVGHTVCCDPYRFITINAPHLTGVC", "length": 370 }, "evidence": [ { "id": "HGNC:3347", "url": "https://alliancegenome.org/gene/HGNC:3347#orthology", "database": "AGR" }, { "id": "MGI:2143333", "url": "https://alliancegenome.org/gene/MGI:2143333#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VAU3-1", "protein_name": "DNA/RNA non-specific endonuclease/pyrophosphatase/phosphodiesterase domain-containing protein", "gene_name": "LP23408p", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLRILLLLLAFCALAHGQCRFTRAQVQGTNRIFMVRGQNRQLSLKRTASSAVGETLQMWCNPRDIVATTCQAGRVPAFQPPLPMTCRAAPAAITTPVQDRRCPATMYRVGYNVGNNQFLELYRACFDTRAVRAIFVEHRVYGKPFYITRPCVQFSSDGVISGADEASYTVRNIHGTFRRLFGNNQNYIPNNRDVIINRGHLAASADFFFGDQLCATFKYVNAVPQFKSINDGNWETIERFVRNSVTGNNFVNVRTGARGVLSLPSGNRPKNVFLSGNRNPVPQWMYKIVRNANNQPIVAFLTLNNIYARQRPAAPNFCQPVNCPVALVNTAQAGFSFCCNPATFRP", "length": 346 }, "evidence": [ { "id": "HGNC:3347", "url": "https://alliancegenome.org/gene/HGNC:3347#orthology", "database": "AGR" }, { "id": "MGI:2143333", "url": "https://alliancegenome.org/gene/MGI:2143333#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VU22-1", "protein_name": "DNA/RNA non-specific endonuclease domain-containing protein", "gene_name": "Dmel\\CG14120", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MWSNRCSIFILALLVASGAVKVSGRLPRILPESLAEGDEGVTVRGDCEFKVNGDLNDPAPLFSRHNSYEIIVPDPTDTVRLVNGELLDMFCPGVGFAAPFVNRWQVTATCLQNKYFLVDDLIYPFANFSCTAWPIFTALRSGKDCNGGTDLVQVGFEVEDGGFLQSYELCHDAEAEATRYVHHVLYPSSYDYQHGVARPNFLELDFYGGRDVNTKYTQVQQNITISNILGLDASPYFNFSDDRILSRGHMIAKTDQIFGAAQHTTFLFINVAPQWQTFNGGNWEKVETSVRKFVADRNLTTDCYTGTWGVSTLPDVDGIERELYLDFDENNNGLIPVPKIYFRVVIDRVTREGIVLIGINNPYLTLEQIQKDYILCQDIGHQLSWLTWYKEDLHEGYSYACSVEDFIEVVKDLPLEDLHTNGILGLDDVTTVEPSTTESSTTTEEPSSTTSTEIPSTTDTTPSSTSVSSTTEEPSSSTASPTTELPTSTVISTTEPPTSTVTSTTKPPTSTVASTTEQPTSTVTSTTEPPTSTVTPTTEPPTSTVTSTTEPSSSTTLEPTSTTSSSTTSQPTLSTEESTSTSPTSTSTSSPPVTTANPIANPCRFSTNGDLKDPAPLLTPQGALSWLLPDESGLYTVEEGSSIDLHCTGALVSPFNRYTALSARCVGDQLYEAEGQLVNIRGFVCQSWPTYAAVRSGQSCAGGTDVVHIGFDVAAGFLSHVELCYDQQEQISRYARYELTPANVAYQKGVAQPGYLRGDFYSGEDVNVLYDQSHQLDAFSTALGLDASQYFDSTKDLYLTRGQLAARLDFVHSSAQRATHFYVNAVPQWRSINIGNWLAVESSLKQFVADEALNVSVHAGSYDISTLPNSQGVQTPLYLNAETKQLPVAKILYRIVIDQESRKGVVLIVVNNPHITLTETLEDYVICEDVGAQIDWLDWDKANLQKGYSYACSVEDFIEVVKDLPTDQLQTTGILGLTDQILDNEVCSFKVNGDLKDPAPLFVVRSELGHARYLEPNQEGVVQLKHGEALEFHCINSFSGPFSGYTFVNSTCWQQQSILAMGSLYQLQDFVCTSWPTYTARRSGRPCNGGTDLLEVGFQLSSSSSDDFLQTYDVCHDELSEVTRYVHHVLYPGSDQYQRSVSRPSFIPGDFYGGKDVNTLYTQVQQNITVSEILGMDASPYFNTTGNVYLARGHLSAKTDFVFGAAQKASFFFVNAAPQWQTFNGGNWERIEDSVRKFVADENITVDCYTGTWGVSTLPDVNGIGRELYLDFDENNNGLIPVPKLYFRVIIDRESRNGIVLLGVNNPHATIEQIEEEYIICQDIGAQLSWVSWTKEDLKKGYSYACTVEDFTAVVKDLPLQDLFVDGVLGV", "length": 1371 }, "evidence": [ { "id": "HGNC:3347", "url": "https://alliancegenome.org/gene/HGNC:3347#orthology", "database": "AGR" }, { "id": "MGI:2143333", "url": "https://alliancegenome.org/gene/MGI:2143333#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VU24-1", "protein_name": "DNA/RNA non-specific endonuclease/pyrophosphatase/phosphodiesterase domain-containing protein", "gene_name": "Dmel\\CG14118", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MMLQFIGLILAVVILREIRAREAIATIPDVGQIIKDLDGLHIDGEMFHQGSPCRVDVQNDLPRLDKVQPLYLRPGTDLYWLPNAYGHLEVQRGASIELHCSHSFAPANGESLDAKLRSIRVKCVQDTTFEWMGAKIHFSDFVCNHSMPYTVERLDRSCGSDTPSPSTSYLYRVGYDTGDGRFVATMELCHDPNQLRTHYAHHQLTPANVHFQKKLKRPRFSTAGHFTGFDMARIYSPKSQEKLMVPGLIDVKSGLFLARGHLTAKADLIYASQQKSSFNYMNVAPQWQSFNGGQWSKLEESTRQYVARSGITATVYTGIYGEMKVAGSKVLHMTTNANNIGVVAVPQLFYRVLIDEGHPTRGIALVGVNNPHATLAQIHESYIICDPVEESVQWLSWLHKSNAKGNLKNGYLYACSVANLARAVGHLPRPLLEVDELLT", "length": 439 }, "evidence": [ { "id": "HGNC:3347", "url": "https://alliancegenome.org/gene/HGNC:3347#orthology", "database": "AGR" }, { "id": "MGI:2143333", "url": "https://alliancegenome.org/gene/MGI:2143333#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VVU9-1", "protein_name": "DNA/RNA non-specific endonuclease domain-containing protein", "gene_name": "Dmel\\CG6839", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKCIRFSLLVVGLLAAPAAWARVPCPEVELPPVVEDDGIFERIAVAPPQPVGRAGACSVTIRGGLPSPEPVYLKTDSEDFYPFSDVGVMEFESGGSLQLWCPSGFNTHSENLLTASCVSGTTFSVGGSNFEFKDLYCKSWPGFKAVKSGATCNGGIVIRVGFEITSSRFAEQMQICFNEEEEVTRYTRHKLEPGSNYYETGVARITFQTAGFFDGKNVDKLYTQATQLETINNELGGDAEKYFDSSSNVYLARGHLGAKADFDYAPEQRATFLFINAAPQWQTFNAGNWARVEDGLRAWVSKNKLNVNCYTGVYGVTTLPNKDGVETPLYLAKDDNNNGLIPVPKLYFRVVIDPSSHRGIVFVGVNNPHLTEEQIKRDYVICDDVSDQVTYINWKTTDIKAGWSYACEVADFLKTVKHLPALTAKGGLLV", "length": 430 }, "evidence": [ { "id": "HGNC:3347", "url": "https://alliancegenome.org/gene/HGNC:3347#orthology", "database": "AGR" }, { "id": "MGI:2143333", "url": "https://alliancegenome.org/gene/MGI:2143333#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y2C4-1", "protein_name": "Nuclease EXOG, mitochondrial", "gene_name": "EXOG", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAIKSIASRLRGSRRFLSGFVAGAVVGAAGAGLAALQFFRSQGAEGALTGKQPDGSAEKAVLEQFGFPLTGTEARCYTNHALSYDQAKRVPRWVLEHISKSKIMGDADRKHCKFKPDPNIPPTFSAFNEDYVGSGWSRGHMAPAGNNKFSSKAMAETFYLSNIVPQDFDNNSGYWNRIEMYCRELTERFEDVWVVSGPLTLPQTRGDGKKIVSYQVIGEDNVAVPSHLYKVILARRSSVSTEPLALGAFVVPNEAIGFQPQLTEFQVSLQDLEKLSGLVFFPHLDRTSDIRNICSVDTCKLLDFQEFTLYLSTRKIEGARSVLRLEKIMENLKNAEIEPDDYFMSRYEKKLEELKAKEQSGTQIRKPS", "length": 368 }, "evidence": [ { "id": "HGNC:3347", "url": "https://alliancegenome.org/gene/HGNC:3347#orthology", "database": "AGR" }, { "id": "MGI:2143333", "url": "https://alliancegenome.org/gene/MGI:2143333#orthology", "database": "AGR" }, { "id": "FB:FBgn0036833", "url": "https://alliancegenome.org/gene/FB:FBgn0036833#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VVV1", "url": "https://www.uniprot.org/uniprotkb/Q9VVV1" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q9VVV1", "url": "https://www.uniprot.org/uniprotkb/Q9VVV1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9VVV1", "url": "https://www.uniprot.org/uniprotkb/Q9VVV1" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "Q9VVV1", "url": "https://www.uniprot.org/uniprotkb/Q9VVV1" } ], "pmid": "" }, { "name": "RNA endonuclease activity", "id": "GO:0004521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004521", "evidence": [ { "database": "UniProtKB", "id": "Q9VVV1", "url": "https://www.uniprot.org/uniprotkb/Q9VVV1" } ], "pmid": "" }, { "name": "single-stranded DNA endodeoxyribonuclease activity", "id": "GO:0000014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000014", "evidence": [ { "database": "UniProtKB", "id": "Q9VVV1", "url": "https://www.uniprot.org/uniprotkb/Q9VVV1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "apoptotic DNA fragmentation", "id": "GO:0006309", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006309", "evidence": [ { "database": "UniProtKB", "id": "Q9VVV1", "url": "https://www.uniprot.org/uniprotkb/Q9VVV1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VVV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVV1" }, { "id": "SM00892", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00892" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DNA/RNA non-specific endonuclease/pyrophosphatase/phosphodiesterase", "eco_id": "ECO_0000259", "start_pos": 163, "end_pos": 406, "start_aa": "Phe", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [ { "evidence": [ { "id": "Q9VVV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVV1#function" }, { "id": "Q9VVV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVV1" }, { "id": "PIRSR640255-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR640255-2" } ], "binding_site_uniprot": 279, "amino_acid": "Asn", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "catalytic", "eco_id": "ECO_0000256", "start_pos": 279, "end_pos": 279, "start_aa": "Asn", "end_aa": "Asn", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VVW2-1", "uniprot_ac": "Q9VVW2", "uniprot_id": "Q9VVW2_DROME", "mass": { "chemical_mass": 71278.0, "monoisotopic_mass": 71278.0 }, "refseq": { "ac": "NP_001287111", "name": "UDP-glycosyltransferase family 316 member A1, isoform B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287111" }, "gene_names": [ { "name": "Ugt316A1", "type": "recommended", "evidence": [ { "id": "Q9VVW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVW2" } ] }, { "name": "CG3797", "type": "synonym", "evidence": [ { "id": "NP_001287111", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287111" }, { "id": "Q9VVW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVW2" } ] }, { "name": "Dmel\\CG3797", "type": "synonym", "evidence": [ { "id": "NP_001287111", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287111" }, { "id": "Q9VVW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVW2" } ] }, { "name": "Dmel_CG3797", "type": "synonym", "evidence": [ { "id": "Q9VVW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVW2" } ] }, { "name": "UGT316A1", "type": "synonym", "evidence": [ { "id": "NP_001287111", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287111" }, { "id": "Q9VVW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVW2" } ] }, { "name": "Ugt316A1", "type": "synonym", "evidence": [ { "id": "NP_001287111", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287111" } ] } ], "protein_names": [ { "name": "CG3797-PB", "type": "synonym", "evidence": [ { "id": "NP_001287111", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287111" } ] }, { "name": "UDP-glycosyltransferase family 316 member A1, isoform A", "type": "synonym", "evidence": [ { "id": "Q9VVW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVW2/entry#names_and_taxonomy" } ] }, { "name": "UDP-glycosyltransferase family 316 member A1, isoform B", "type": "synonym", "evidence": [ { "id": "NP_001287111", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287111" }, { "id": "Q9VVW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVW2/entry#names_and_taxonomy" } ] }, { "name": "Ugt316A1-PB", "type": "synonym", "evidence": [ { "id": "NP_001287111", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287111" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VVW2", "url": "https://www.uniprot.org/uniprotkb/Q9VVW2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Ugt316A1", "url": "https://www.uniprot.org/uniprotkb/Q9VVW2", "locus": { "chromosome": "3L", "start_pos": 19059400, "end_pos": 19062816, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0036842", "url": "https://www.ensemblgenomes.org/id/FBgn0036842" } ] } } ], "crossref": [ { "id": "FB:FBgn0036842", "url": "https://alliancegenome.org/gene/FB:FBgn0036842", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0036842", "url": "https://bgee.org/?page=gene&gene_id=FBgn0036842", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03784", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03784", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0036842", "url": "https://flybase.org/reports/FBgn0036842", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "40079", "url": "https://www.ncbi.nlm.nih.gov/gene/40079", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG3797", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3797", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MRSQSVM", "url": "https://omabrowser.org/oma/group/MRSQSVM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VVW2", "url": "https://www.orthodb.org/?gene=Q9VVW2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48043", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48043", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48043:SF159", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48043:SF159", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00201", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00201", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-9753281", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9753281", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-9757110", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9757110", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-9840309", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9840309", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001287111", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287111", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VVW2", "url": "https://www.uniprot.org/uniprotkb/Q9VVW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VVW2-1", "url": "https://www.uniprot.org/uniprotkb/Q9VVW2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQILQVFLGTLLCGIVLGANVLTVFPSVWKSHYLFGRRLLQELVESSGNHSVTLISPHAAQEGVDAEIPKIRELRIEGLRENWLDMGMSFEAEEMRAQSVMERFTRLIYAGTTNVDILLSDPQVRKLLTSGEKFDLLIVDLFLSDALLGLAFYYGIPTVAVSPTGANSWLNNMFGNPQSSSLDPSNFLPFTERMNTRQRILNSLMSTFERLTYNFFHLISQQSVYTNHFELLVKELPLYRDLTKNLSLALINSHPGLHYPRAYLPNMVEVGGLHLSHLNDDNLPKHLLSFMESAPSGVIYFSLGADVETAQLPQEKLAIILDVFGHLKEFHFLLKWEKEEFTAEQVLPENVMIADWWPQQAILHHPQVKMFISSCGQLSVWESISGQKPVLAIPILAEQEVMAKRLQRHGVSVTVGYDSLAYDSLLHGIRQLTLNTSYVEKLGQLKERLISRDSTPVGKAVRKIQLILESGGADFLKSHANTLNFWRAEGVDVLLIIAVGFFGILTIPFLAICFILRKSYHSQAAQDQPPYRTNLKVVGRVHSYGDQGSSRSPKGTESLRRTRSAQSLSARSSSSSMSSNSPTSPSTASTTPLDLTPPPPIQLLGQVPPLQLYVNQQRIYSSDRKTSQEEAERRFS", "length": 636, "header": "tr|Q9VVW2-1|Q9VVW2_DROME Isoform 1 of UDP-glycosyltransferase family 316 member A1, isoform A OS=Drosophila melanogaster OX=7227 GN=Ugt316A1 PE=3 SV=1 CANONICAL=Q9VVW2-1" }, "isoforms": [ { "isoform_ac": "Q9VVW2-1", "url": "https://www.uniprot.org/uniprotkb/Q9VVW2/entry#Q9VVW2-1", "sequence": { "sequence": "MQILQVFLGTLLCGIVLGANVLTVFPSVWKSHYLFGRRLLQELVESSGNHSVTLISPHAAQEGVDAEIPKIRELRIEGLRENWLDMGMSFEAEEMRAQSVMERFTRLIYAGTTNVDILLSDPQVRKLLTSGEKFDLLIVDLFLSDALLGLAFYYGIPTVAVSPTGANSWLNNMFGNPQSSSLDPSNFLPFTERMNTRQRILNSLMSTFERLTYNFFHLISQQSVYTNHFELLVKELPLYRDLTKNLSLALINSHPGLHYPRAYLPNMVEVGGLHLSHLNDDNLPKHLLSFMESAPSGVIYFSLGADVETAQLPQEKLAIILDVFGHLKEFHFLLKWEKEEFTAEQVLPENVMIADWWPQQAILHHPQVKMFISSCGQLSVWESISGQKPVLAIPILAEQEVMAKRLQRHGVSVTVGYDSLAYDSLLHGIRQLTLNTSYVEKLGQLKERLISRDSTPVGKAVRKIQLILESGGADFLKSHANTLNFWRAEGVDVLLIIAVGFFGILTIPFLAICFILRKSYHSQAAQDQPPYRTNLKVVGRVHSYGDQGSSRSPKGTESLRRTRSAQSLSARSSSSSMSSNSPTSPSTASTTPLDLTPPPPIQLLGQVPPLQLYVNQQRIYSSDRKTSQEEAERRFS", "length": 636, "header": "tr|Q9VVW2-1|Q9VVW2_DROME Isoform 1 of UDP-glycosyltransferase family 316 member A1, isoform A OS=Drosophila melanogaster OX=7227 GN=Ugt316A1 PE=3 SV=1 CANONICAL=Q9VVW2-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 164, "start_aa": "Thr", "end_pos": 164, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr164", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 414, "start_aa": "Thr", "end_pos": 414, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr414", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycosyltransferase-activity", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VVW2", "url": "https://www.uniprot.org/uniprotkb/Q9VVW2" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VVW2", "url": "https://www.uniprot.org/uniprotkb/Q9VVW2" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVW2", "url": "https://www.uniprot.org/uniprotkb/Q9VVW2" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVW2", "url": "https://www.uniprot.org/uniprotkb/Q9VVW2" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VVW2", "url": "https://www.uniprot.org/uniprotkb/Q9VVW2" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VVW2", "url": "https://www.uniprot.org/uniprotkb/Q9VVW2" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VVW2", "url": "https://www.uniprot.org/uniprotkb/Q9VVW2" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVW2", "url": "https://www.uniprot.org/uniprotkb/Q9VVW2" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVW2", "url": "https://www.uniprot.org/uniprotkb/Q9VVW2" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VVW2", "url": "https://www.uniprot.org/uniprotkb/Q9VVW2" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VVW2", "url": "https://www.uniprot.org/uniprotkb/Q9VVW2" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG3797", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3797", "resource": "KEGG Pathway" }, { "id": "R-DME-9753281", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9753281", "resource": "Reactome", "description": "Paracetamol ADME" }, { "id": "R-DME-9757110", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9757110", "resource": "Reactome", "description": "Prednisone ADME" }, { "id": "R-DME-9840309", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9840309", "resource": "Reactome", "description": "Glycosphingolipid biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JW02-1", "protein_name": "glucuronosyltransferase", "gene_name": "Ugt2a3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGGRHTMVSVKWAVAIFLLQLCWSGCGICSKVLVWPCDMSHWLNLKTILEELAARGHEVTVLKYPSIIIDQSKLTPLQFENIPVLYETEVAENHLNEIVNLAVNVIPNLSLWEAARTLQDFFLQLTGNFEDLCRSTLYNQTLMNKLRDAKYDVMVLDPVIPCGELVAEVLQIPFVNTLRFSMGYSMEKYCGQLPVPLSYVPVVMGELTDHMTFTERVKNMMLSLFFEFWLQQYDFAFWDQFYSKTLGRPTTFCKTVGKAEIWLIRTYWDIEFPRPYLPNFEFVGGLHCKPAKPLPKELEEFVQSSGEHGVVVFSLGSMIKNLTEEKANLIASALAQIPQKVLWRYSGKKPATLGPNTRILNWIPQNDLLGHPKTRAFITHGGTNGIYEAIYHGVPMVGIPMFGDQPYNIAHMEAKGAAVKVAINTMTSADLLSALRAVINEPSYKENAMRLSRVHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSLDVIGFLLVCVVTLTFVITKCSLFMCRKCCLRERKKKGNRKKKN", "length": 541 }, "evidence": [ { "id": "HGNC:28528", "url": "https://alliancegenome.org/gene/HGNC:28528#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M1NVN7-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "ugt1a5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASVLLFCLFCLASAKAGKILVVPSDGSHWMGIKPLVEELGRRGNQVVVVIPEASLSMGPSQHTTTLTYPVPYTKAQIQDHISASVTNLISTHVSTDLARFQSFINTMDLLSNLITRNVEGLLLNKDLMKKLQDYNFDVILTDPFETVGVIAAEYLSIPTIYIQTSHPCGADTLASQCPSPPSYVPQRLTHFSDRMNLWQRSVNFVRTLIQPMACRRMFTRADEIASRVLQRKTSIMDIMGRAALWFVHSDFALEFPHPLMPNMIIVGGMDNRKAEPLSQELEEFVNGSGEHGFVVFTLGSMVSQLPEAKAREFFEAFRQIPQRVLWRYTGPVPENAPKNVKLMKWLPQNDLLGHPKVRAFVTHGGSHGIYEGICNGVPMVMLPLFGDQGDNAQRLVSRGVAESLTIYDVTSEKLLVALKKVINDKSYKEKMMKLSAIHRDRPIEPLDLAVFWTEFVMRHKGAEHLRPAAHDLNWIQYHSLDVIGFLLLILLTVIFVTVKSCMFCFRKCFKKSQKKKKA", "length": 519 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" }, { "id": "FB:FBgn0036842", "url": "https://alliancegenome.org/gene/FB:FBgn0036842#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1NX95-1", "protein_name": "glucuronosyltransferase", "gene_name": "ugt2a1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSPRGSTGVFLLLALLLNQNLLCVSGGKILVWPAEFSHWLNIKVILDVLIERGHNITVVTHTATPSVQTTPSAGYNAEILQVPYTKQEIVDNLERMLKYWTHDLPNDNIITASLKIHEMITTATAQNKITCNALFSRADLLEKWKMEKFDVILADPLYICGEILAQKLDIPLIFSLRFTFGNTLERLCGQMPAPPSYVPAVASEKTDQMDFIDRLKNFLFYGMQDFLFYLVTKFKWDHYYSEVLGKPTTMCETMGKADIWLIRTYWDFEYPRPFPPNFKFVGGLHCKPAKPLSKEMEEFVQSSGDHGVVVFSLGSMIKNLTSERANTIAAALGQIPQKVVWRYSGKTPETLAPNTKIYDWIPQNDLLGHPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFADQPDNLLHMKTKGAAVVLDINTLESKDLVDALKTVLNNPSYKESIMRLSRIHHDQPMKPLDQAVYWIEFVMRNKGAKHLRVQAHELSWYQYHCLDVAAFLLSIAALITFLWVKACCFLFRRCVRKTRPERKTQKSKNE", "length": 539 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12544", "url": "https://alliancegenome.org/gene/HGNC:12544#orthology", "database": "AGR" }, { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "HGNC:28528", "url": "https://alliancegenome.org/gene/HGNC:28528#orthology", "database": "AGR" }, { "id": "HGNC:12554", "url": "https://alliancegenome.org/gene/HGNC:12554#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB12ZY70-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "ugt2b6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRPLACFLSLLSLLSAGECGNVLVWFTEGSHWINMKIVLETLIDRGHDVTVLVPDASLFMKANASDRFSYQPFNVSMDEQEMKVFIEEFLYFSLYEMDQLNFFQMQSKVYEFTSKLQDMSISYCDGVLKSPGLLDKLRKHKFDVVFSDPIYQCSDIVAEELNVPLVYTFRFSLAHAAERMCGQIPAPPSYVPGAMSKLTDKMSFTERIYNMLFYLSQDAFAIFAWKKIDNYYTEYFGRPTSYCEMMGRADIWLIRTYWDFEFPRPFVPNFKYIGGLHCTPAKPLPKDMEEFVQSSGEDGIVVFTLGSLVGKVPKEISNRIASALAQIPQKVLWRYGGEKPDTLGENTRIYKWIPQNDLLGHPKTRAFITHGGTNGVYEAIYHGVPMVGIPLFGDQPDNMVHMTTRGAAVVVDSIKSMQPQELVDKLNTVINDPSYKENAMRLSRIHHDRPMKPLDESVFWIEFVMRNKGAKHLRVEAHNLTWYQYHCLDVFAFLTTVLTLVLYICFKMAKFFIMRCCFRSKRKSKKE", "length": 527 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12544", "url": "https://alliancegenome.org/gene/HGNC:12544#orthology", "database": "AGR" }, { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "HGNC:28528", "url": "https://alliancegenome.org/gene/HGNC:28528#orthology", "database": "AGR" }, { "id": "HGNC:12554", "url": "https://alliancegenome.org/gene/HGNC:12554#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" }, { "id": "FB:FBgn0036842", "url": "https://alliancegenome.org/gene/FB:FBgn0036842#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABK0L4Q8-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "LOC134478834", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFKMPRKWISALFLLQISYCFKSGHCGKVLVWPMDFSHWMNIKIILDELVQRGHEVTVLKPSAYFFLDPKKSSDLKFEIFPTSISKDELQNHFIKLLDVWTYELPRDTCLSYSPILQNLVYEFSYFYLSICKDAVSNKQLMTKLQESKFDVLFADPVASCGDLIAELLHIPFLYSLSFSPGHKLEKSIGKFILPPSYVPVILSGLAGKMTFIDRVKNMICMLYFDFWFERLRHKEWDTFYSEILGRPTTVDETMSKVEIWLIRSYWDLKFPHPTLPNVDYIGGLHCKPAKPLPKDMEEFVQSSGEHGVVVFSLGSMVSNMTEEKANAIAWALAQIPQKVLWKFDGKTPATLGPNTRVYKWLPQNDILGHPKTKAFVTHGGANGLYEAIYHGIPMIGIPLFGDQPDNIAHMVAKGAAVSLNIRTMSKLDFLSALEEVIDNPFYKKNVMLLSTIHHDQPMKPLDRAVFWIEFIMRHKGAKHLRPLGHNLPWYQYHSLDVIGFLLTCFAVIAALTVKCLLFMYRFFVKKEKKMKNE", "length": 533 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12544", "url": "https://alliancegenome.org/gene/HGNC:12544#orthology", "database": "AGR" }, { "id": "HGNC:12554", "url": "https://alliancegenome.org/gene/HGNC:12554#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LGK3-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt2b37", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPGKWIFALLLLQISFCLRSAKCGKVLVWPMEFSHWMNIKTILDELVQRGHEVTVLKPSAYYVLDPKKSPDLKFETFPTSVSKDELEKYFIKLVDAWTYELQRDTCLSFSPLLQNMMDEFSDYYLSVCKDAVSNKQLMAKLQESKFDVLLSDPVAACGELIAEVLHIPFLYSLRASPGHKIEKSSGRFILPPSYVPVILSGLGGQMTFIDRVKNMICMLYFDFWFHMFNAKNWDPFYTEILGRPTTLAETMGKAEMWLIRSYWDLEFPHPTLPNVDYIGGLQCKPAKPLPKDIEDFVQSSGEHGVVVFSLGSMVSSMTEEKANAVAWALAQIPQKVLWKFDGKIPATLGPNTRVYKWLPQNDLLGHPKTKAFVTHGGANGVYEAIYHGIPMIGIPMFGEQHDNIAHMVAKGAAVTLNIRTMSKSDLFNALKEVINNPFYKKNAMWLSTIHHDQPMKPLDKAIFWIEYVMRHKRAKHLRPLGHNLPWYQYHSLDVIGFLLACLAVIAALAVKCFLFIYRFFAKKQKKMKNE", "length": 530 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12544", "url": "https://alliancegenome.org/gene/HGNC:12544#orthology", "database": "AGR" }, { "id": "HGNC:12554", "url": "https://alliancegenome.org/gene/HGNC:12554#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B8JMA2-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "ugt2a5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTSGALLVCLLLCGVDVGWSGRVLVMPGEYSHWHNMRPVIEALVDKNHSVTVLVGSSSPTVPHTQKERFEYHVFKVNMEKEEADAAMRDMIHLFTNDTAAKYEGEFVMWKVMSKFVEFGDVYFRGLFDVGLLKTLRDSNYDVLFSDPMMPFSDLMAQKLNIPQVISMRATFAYAAERLCGQMPAPPSYVPAVALTDHLTDRMSFMERVENMLLYIVHSIAFPLVATFTFDGYYSEILGKPTTMCETMGKVDICLIRTYWDFEYPRPFPPNFKFVGGLHCKPAKPLSKELEEFVQSSGDHGVVVFSLGSMIKNLTSERANTIAAALGQIPQKVVWRYSGKTPETLAPNTKIYDWIPQNDLLGHPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFGDQPDNLLHIKTKGAAVVLDIHTMGSKDLVDALKAVVNNPSYKESIMRLSRIHHDQPMKPLDQAVYWIEFVMRNKGAKHLRVQAHELSWYQYHCLDVAAFLLSITALITFLWVKACCFLFRRCVRKTRPERKRQKNKKE", "length": 532 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12544", "url": "https://alliancegenome.org/gene/HGNC:12544#orthology", "database": "AGR" }, { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "HGNC:28528", "url": "https://alliancegenome.org/gene/HGNC:28528#orthology", "database": "AGR" }, { "id": "HGNC:12554", "url": "https://alliancegenome.org/gene/HGNC:12554#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3Z748-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt1a8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPAVFPASLPLRVCLLLAFGLAQAGRLLVVPMDGSHWFSMKMIVEKLSHRGHEVVVVIPEVSWHLGKSQNFTVKTYSVSYTLEDLSHHFNFFAHKQWENREVGMFSLLKHSGKGFFQVLFSHCRSLFNDKKLVEYLKQRSFDAVFLDPFDVCGLTIAKYFSLPSVVFSGGIFCHYLDEGAQCPSPPSYVPRILSKFADTMTFKERVWNYFSYMKERAFCPYFFKTAIEIASEVLQTPVTMTDLFSSVSIWMFRTDFVLEFPRPVMPNMVYIGGINCHPGKPLSKEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVFKCCAYGCRKCFGGKGRVKKSHKSKTH", "length": 530 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1LTB8-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt2b34l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVKMTAALLLLHLTIFFGSGSGGKVLVWPVEFSHWLNLKIILSELVKKGHEVVVLKPSVSFSYEVDKTSAIEFESFPSSYSIADVEVIFMDCVNESIYELPKQSFWGYFLMLQKLFERTSDYSERLCRDAAFNKELMTKLQNSGFDVILADPFTPCGDLLAEILKIPLVYSLRFFPGSTYEKYSGGLPMPPSYVPIAMSELSDRMTFVERVKHMIYVLCFDFWFQVFDEKKWNELYTEVLGRPTTLSETMAKADIWLIRTYWDLEFPHPVLPNFDFVGGLHCRPAKPLPKEIEDFVQSSGEHGVVVFSLGSMVGSLTEERANVIAAGLAQIPQKVLWRFEGKKPETLGSNTRLYKWIPQNDLLGHPKTRAFITHGGTNGIYEAIYHGIPVVGIPLFGDQKDNIVHLKTKGAAVRLDFLTMSSTDLLTALRTVTNDPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAGHDLSWVQYHSLDVIGFLLACVVTVMFILKKCCLFCCQKFTKAGRKKKKE", "length": 530 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "K9J7B2-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt1a6b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MACLLPAAQTLPAGFLFLVLWASVLGDKLLVVPQDGSHWLSMKEIVEHLSERGHDIVVLVPEVNLLLGESKYYRRKIFSVPYSLEELQTRFRTFGRNQFVPGAPLMGPLREYRNSMLTLEMFFSNCQSLLKDSATLSFLRENKFDALFTDPAMPCGVILAEYLNLPSVYLFRGFPCSLEHMLGQSPSPVSYVPRFYTKFSDHMTFPQRLANFIVNILENYLYYCLYSKYEIIVTDLLKRDVSLPSLHQNSLWLLRYDFVFEYPRPIMPNMIFIGGINCKKKGKLTQEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVFKCCAYGCRKCFGGKGRVKKSHKSKTH", "length": 531 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O60656-1", "protein_name": "UDP-glucuronosyltransferase 1A9", "gene_name": "UGT1A9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MACTGWTSPLPLCVCLLLTCGFAEAGKLLVVPMDGSHWFTMRSVVEKLILRGHEVVVVMPEVSWQLGRSLNCTVKTYSTSYTLEDLDREFKAFAHAQWKAQVRSIYSLLMGSYNDIFDLFFSNCRSLFKDKKLVEYLKESSFDAVFLDPFDNCGLIVAKYFSLPSVVFARGILCHYLEEGAQCPAPLSYVPRILLGFSDAMTFKERVRNHIMHLEEHLLCHRFFKNALEIASEILQTPVTEYDLYSHTSIWLLRTDFVLDYPKPVMPNMIFIGGINCHQGKPLPMEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH", "length": 530 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O75310-1", "protein_name": "UDP-glucuronosyltransferase 2B11", "gene_name": "UGT2B11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTLKWTSVLLLIHLSCYFSSGSCGKVLVWAAEYSHWMNMKTILKELVQRGHEVTVLASSASILFDPNDASTLKFEVYPTSLTKTEFENIIMQQVKRWSDIRKDSFWLYFSQEQEILWELYDIFRNFCKDVVSNKKVMKKLQESRFDIVFADAVFPCGELLAALLNIRFVYSLRFTPGYTIERHSGGLIFPPSYIPIVMSKLSDQMTFMERVKNMIYVLYFDFWFQMSDMKKWDQFYSEVLGRPTTLFETMGKADIWLMRNSWSFQFPHPFLPNVDFVGGFHCKPAKPLPKEMEEFVQSSGENGVVVFSLGSVISNMTAERANVIATALAKIPQKVLWRFDGNKPDALGLNTRLYKWIPQNDLLGHPKTRAFITHGGANGIYEAIYHGIPMVGIPLFFDQPDNIAHMKAKGAAVRLDFNTMSSTDLLNALKTVINDPLYKENIMKLSRIQHDQPVKPLDRAVFWIEFVMPHKGAKHLRVAAHDLTWFQYHSLDVIGFLLACVATVIFIITKFCLFCFWKFARKGKKGKRD", "length": 529 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O75795-1", "protein_name": "UDP-glucuronosyltransferase 2B17", "gene_name": "UGT2B17", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLKWMSVFLLMQLSCYFSSGSCGKVLVWPTEYSHWINMKTILEELVQRGHEVIVLTSSASILVNASKSSAIKLEVYPTSLTKNDLEDFFMKMFDRWTYSISKNTFWSYFSQLQELCWEYSDYNIKLCEDAVLNKKLMRKLQESKFDVLLADAVNPCGELLAELLNIPFLYSLRFSVGYTVEKNGGGFLFPPSYVPVVMSELSDQMIFMERIKNMIYMLYFDFWFQAYDLKKWDQFYSEVLGRPTTLFETMGKAEMWLIRTYWDFEFPRPFLPNVDFVGGLHCKPAKPLPKEMEEFVQSSGENGIVVFSLGSMISNMSEESANMIASALAQIPQKVLWRFDGKKPNTLGSNTRLYKWLPQNDLLGHPKTKAFITHGGTNGIYEAIYHGIPMVGIPLFADQHDNIAHMKAKGAALSVDIRTMSSRDLLNALKSVINDPIYKENIMKLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHNLTWIQYHSLDVIAFLLACVATMIFMITKCCLFCFRKLAKTGKKKKRD", "length": 530 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P06133-1", "protein_name": "UDP-glucuronosyltransferase 2B4", "gene_name": "UGT2B4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSMKWTSALLLIQLSCYFSSGSCGKVLVWPTEFSHWMNIKTILDELVQRGHEVTVLASSASISFDPNSPSTLKFEVYPVSLTKTEFEDIIKQLVKRWAELPKDTFWSYFSQVQEIMWTFNDILRKFCKDIVSNKKLMKKLQESRFDVVLADAVFPFGELLAELLKIPFVYSLRFSPGYAIEKHSGGLLFPPSYVPVVMSELSDQMTFIERVKNMIYVLYFEFWFQIFDMKKWDQFYSEVLGRPTTLSETMAKADIWLIRNYWDFQFPHPLLPNVEFVGGLHCKPAKPLPKEMEEFVQSSGENGVVVFSLGSMVSNTSEERANVIASALAKIPQKVLWRFDGNKPDTLGLNTRLYKWIPQNDLLGHPKTRAFITHGGANGIYEAIYHGIPMVGVPLFADQPDNIAHMKAKGAAVSLDFHTMSSTDLLNALKTVINDPLYKENAMKLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLTWFQYHSLDVTGFLLACVATVIFIITKCLFCVWKFVRTGKKGKRD", "length": 528 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "FB:FBgn0036842", "url": "https://alliancegenome.org/gene/FB:FBgn0036842#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P08430-1", "protein_name": "UDP-glucuronosyltransferase 1A6", "gene_name": "Ugt1a6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MACLLPAARLPAGFLFLVLWGSVLGDKLLVVPQDGSHWLSMKEIVEHLSERGHDIVVLVPEVNLLLGESKYYRRKSFPVPYNLEELRTRYRSFGNNHFAASSPLMAPLREYRNNMIVIDMCFFSCQSLLKDSATLSFLRENQFDALFTDPAMPCGVILAEYLKLPSIYLFRGFPCSLEHIGQSPSPVSYVPRFYTKFSDHMTFPQRLANFIANILENYLYHCLYSKYEILASDLLKRDVSLPALHQNSLWLLRYDFVFEYPRPVMPNMIFIGGTNCKKKGNLSQEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTLLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKARAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVYKSCAYGCRKCFGGKGRVKKSHKSKTH", "length": 529 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P08542-1", "protein_name": "UDP-glucuronosyltransferase 2B17", "gene_name": "Ugt2b17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPGKWISALLLLQISCCFQSGNCGKVLVWPMEFSHWMNIKTILDELVQRGHEVTVLKPSAYYVLDPKKSPDLKFETFPTSVSKDELENYFIKLVDVWTYELQRDTCLSYSPLLQNMIDGFSDYYLSLCKDTVSNKQLMAKLQESKFDVLLSDPVAACGELIAEVLHIPFLYSLRFSPGYKIEKSSGRFILPPSYVPVILSGMGGPMTFIDRVKNMICTLYFDFWFHMFNAKKWDPFYSEILGRPTTLAETMGKAEMWLIRSYWDLEFPHPTLPNVDYIGGLQCRPPKPLPKDMEDFVQSSGEHGVVVFSLGSMVSSMTEEKANAIAWALAQIPQKVLWKFDGKTPATLGPNTRVYKWLPQNDLLGHPKTKAFVTHSGANGVYEAIYHGIPMVGIPMFGEQHDNIAHMVAKGAAVTLNIRTMSKSDLFNALKEIINNPFYKKNAVWLSTIHHDQPMKPLDKAVFWIEFVMRHKGAKHLRPLGHDLPWYQYHSLDVIGFLLTCSAVIAVLTVKCFLFIYRLFVKKEKKMKNE", "length": 530 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12544", "url": "https://alliancegenome.org/gene/HGNC:12544#orthology", "database": "AGR" }, { "id": "HGNC:12554", "url": "https://alliancegenome.org/gene/HGNC:12554#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P09875-1", "protein_name": "UDP-glucuronosyltransferase 2B1", "gene_name": "Ugt2b1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSMKQTSVFLLIQLICYFRPGACGKVLVWPTEYSHWINIKIILNELAQRGHEVTVLVSSASILIEPTKESSINFEIYSVPLSKSDLEYSFAKWIDEWTRDFETLSIWTYYSKMQKVFNEYSDVVENLCKALIWNKSLMKKLQGSQFDVILADAVGPCGELLAELLKTPLVYSLRFCPGYRCEKFSGGLPLPPSYVPVVLSELSDRMTFVERVKNMLQMLYFDFWFQPFKEKSWSQFYSDVLGRPTTLTEMMGKADIWLIRTFWDLEFPHPFLPNFDFVGGLHCKPAKPLPREMEEFVQSSGEHGVVVFSLGSMVKNLTEEKANVVASALAQIPQKVVWRFDGKKPDTLGSNTRLYKWIPQNDLLGHPKTKAFVAHGGTNGIYEAIYHGIPIVGIPLFADQPDNINHMVAKGAAVRVDFSILSTTGLLTALKIVMNDPSYKENAMRLSRIHHDQPVKPLDRAVFWIEYVMRHKGAKHLRSTLHDLSWFQYHSLDVIGFLLLCVVGVVFIITKFCLFCCRKTANMGKKKKE", "length": 529 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12544", "url": "https://alliancegenome.org/gene/HGNC:12544#orthology", "database": "AGR" }, { "id": "HGNC:12554", "url": "https://alliancegenome.org/gene/HGNC:12554#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0DTE4-5", "protein_name": "UDP-glucuronosyltransferase 2A1", "gene_name": "UGT2A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLNNLLLFSLQISLIGTTLGGNVLIWPMEGSHWLNVKIIIDELIKKEHNVTVLVASGALFITPTSNPSLTFEIYKVPFGKERIEGVIKDFVLTWLENRPSPSTIWRFYQEMAKVIKDFHMVSQEICDGVLKNQQLMAKLKKSKFEVLVSDPVFPCGDIVALKLGIPFMYSLRFSPASTVEKHCGKVPYPPSYVPAVLSELTDQMSFTDRIRNFISYHLQDYMFETLWKSWDSYYSKALGGLLLCCPGWSAVADLGSLQPLLPGFKRFSRLSLHCSWDYRLPAGRPTTLCETMGKAEIWLIRTYWDFEFPRPYLPNFEFVGGLHCKPAKPLPKVLWRYKGKKPATLGNNTQLFDWIPQNDLLGHPKTKAFITHGGTNGIYEAIYHGVPMVGVPMFADQPDNIAHMKAKGAAVEVNLNTMTSVDLLSALRTVINEPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLTWFQYHSLDVIGFLLVCVTTAIFLVIQCCLFSCQKFGKIGKKKKRE", "length": 527 }, "evidence": [ { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" }, { "id": "FB:FBgn0036842", "url": "https://alliancegenome.org/gene/FB:FBgn0036842#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DTE5-1", "protein_name": "UDP-glucuronosyltransferase 2A2", "gene_name": "UGT2A2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVSIRDFTMPKKFVQMLVFNLTLTEVVLSGNVLIWPTDGSHWLNIKIILEELIQRNHNVTVLASSATLFINSNPDSPVNFEVIPVSYKKSNIDSLIEHMIMLWIDHRPTPLTIWAFYKELGKLLDTFFQINIQLCDGVLKNPKLMARLQKGGFDVLVADPVTICGDLVALKLGIPFMYTLRFSPASTVERHCGKIPAPVSYVPAALSELTDQMTFGERIKNTISYSLQDYIFQSYWGEWNSYYSKILGRPTTLCETMGKAEIWLIRTYWDFEFPRPYLPNFEFVGGLHCKPAKPLPKEMEEFIQSSGKNGVVVFSLGSMVKNLTEEKANLIASALAQIPQKVLWRYKGKKPATLGNNTQLFDWIPQNDLLGHPKTKAFITHGGTNGIYEAIYHGVPMVGVPMFADQPDNIAHMKAKGAAVEVNLNTMTSVDLLSALRTVINEPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLTWFQYHSLDVIGFLLVCVTTAIFLVIQCCLFSCQKFGKIGKKKKRE", "length": 536 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P16662-1", "protein_name": "UDP-glucuronosyltransferase 2B7", "gene_name": "UGT2B7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSVKWTSVILLIQLSFCFSSGNCGKVLVWAAEYSHWMNIKTILDELIQRGHEVTVLASSASILFDPNNSSALKIEIYPTSLTKTELENFIMQQIKRWSDLPKDTFWLYFSQVQEIMSIFGDITRKFCKDVVSNKKFMKKVQESRFDVIFADAIFPCSELLAELFNIPFVYSLSFSPGYTFEKHSGGFIFPPSYVPVVMSELTDQMTFMERVKNMIYVLYFDFWFEIFDMKKWDQFYSEVLGRPTTLSETMGKADVWLIRNSWNFQFPYPLLPNVDFVGGLHCKPAKPLPKEMEDFVQSSGENGVVVFSLGSMVSNMTEERANVIASALAQIPQKVLWRFDGNKPDTLGLNTRLYKWIPQNDLLGHPKTRAFITHGGANGIYEAIYHGIPMVGIPLFADQPDNIAHMKARGAAVRVDFNTMSSTDLLNALKRVINDPSYKENVMKLSRIQHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLTWFQYHSLDVIGFLLVCVATVIFIVTKCCLFCFWKFARKAKKGKND", "length": 529 }, "evidence": [ { "id": "HGNC:12554", "url": "https://alliancegenome.org/gene/HGNC:12554#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "FB:FBgn0036842", "url": "https://alliancegenome.org/gene/FB:FBgn0036842#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P17717-1", "protein_name": "UDP-glucuronosyltransferase 2B17", "gene_name": "Ugt2b17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPGKWISALLLLQISCCFRSVKCGKVLVWPMEFSHWMNIKIILDELVQRGHEVTVLRPSAYYVLDPKKSPGLKFETFPTSVSKDNLENFFIKFVDVWTYEMPRDTCLSYSPLLQNMIDEFSDYFLSLCKDVVSNKELMTKLQESKFDVLLSDPVASCGELIAELLQIPFLYSIRFSPGYQIEKSSGRFLLPPSYVPVILSGLGGQMTFIERIKNMICMLYFDFWFQMFNDKKWDSFYSEYLGRPTTLVETMGQAEMWLIRSNWDLEFPHPTLPNVDYVGGLHCKPAKPLPKDMEEFVQSSGDHGVVVFSLGSMVSNMTEEKANAIAWALAQIPQKVLWKFDGKTPATLGHNTRVYKWLPQNDLLGHPKTKAFVTHGGANGVYEAIYHGIPMIGIPLFGEQHDNIAHMVAKGAAVALNIRTMSKSDVLNALEEVIENPFYKKNAIWLSTIHHDQPMKPLDRAVFWIEFVMRHKRAKHLRPLGHNLTWYQYHSLDVIGFLLSCVATTIVLSVKCLLFIYRFFVKKENKMKNE", "length": 530 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12544", "url": "https://alliancegenome.org/gene/HGNC:12544#orthology", "database": "AGR" }, { "id": "HGNC:12554", "url": "https://alliancegenome.org/gene/HGNC:12554#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P19224-1", "protein_name": "UDP-glucuronosyltransferase 1A6", "gene_name": "UGT1A6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MACLLRSFQRISAGVFFLALWGMVVGDKLLVVPQDGSHWLSMKDIVEVLSDRGHEIVVVVPEVNLLLKESKYYTRKIYPVPYDQEELKNRYQSFGNNHFAERSFLTAPQTEYRNNMIVIGLYFINCQSLLQDRDTLNFFKESKFDALFTDPALPCGVILAEYLGLPSVYLFRGFPCSLEHTFSRSPDPVSYIPRCYTKFSDHMTFSQRVANFLVNLLEPYLFYCLFSKYEELASAVLKRDVDIITLYQKVSVWLLRYDFVLEYPRPVMPNMVFIGGINCKKRKDLSQEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH", "length": 532 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P20720-1", "protein_name": "UDP-glucuronosyltransferase 1-2", "gene_name": "Ugt1a2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTGLCAPLRGLSGLLLLLCALPWAEGGKVLVFPMEGSHWLSMRDVVRELHARGHQAVVLAPEVTVHMKGEDFFTLQTYAFPYTKEEYQREILGNAKKGFEPQHFVKTFFETMASIKKFFDLYANSCAALLHNKTLIQQLNSSSFDVVLTDPVFPCGALLAKYLQIPAVFFLRSVPCGIDYEATQCPKPSSYIPNLLTMLSDHMTFLQRVKNMLYPLTLKYICHLSITPYESLASELLQREMSLVEVLSHASVWLFRGDFVFDYPRPIMPNMVFIGGINCVIKKPLSQEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTLLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKARAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVYKSCAYGCRKCFGGKGRVKKSHKSKTH", "length": 533 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P22309-1", "protein_name": "UDP-glucuronosyltransferase 1A1", "gene_name": "UGT1A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVESQGGRPLVLGLLLCVLGPVVSHAGKILLIPVDGSHWLSMLGAIQQLQQRGHEIVVLAPDASLYIRDGAFYTLKTYPVPFQREDVKESFVSLGHNVFENDSFLQRVIKTYKKIKKDSAMLLSGCSHLLHNKELMASLAESSFDVMLTDPFLPCSPIVAQYLSLPTVFFLHALPCSLEFEATQCPNPFSYVPRPLSSHSDHMTFLQRVKNMLIAFSQNFLCDVVYSPYATLASEFLQREVTVQDLLSSASVWLFRSDFVKDYPRPIMPNMVFVGGINCLHQNPLSQEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH", "length": 533 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P22310-1", "protein_name": "UDP-glucuronosyltransferase 1A4", "gene_name": "UGT1A4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARGLQVPLPRLATGLLLLLSVQPWAESGKVLVVPTDGSPWLSMREALRELHARGHQAVVLTPEVNMHIKEEKFFTLTAYAVPWTQKEFDRVTLGYTQGFFETEHLLKRYSRSMAIMNNVSLALHRCCVELLHNEALIRHLNATSFDVVLTDPVNLCGAVLAKYLSIPAVFFWRYIPCDLDFKGTQCPNPSSYIPKLLTTNSDHMTFLQRVKNMLYPLALSYICHTFSAPYASLASELFQREVSVVDLVSYASVWLFRGDFVMDYPRPIMPNMVFIGGINCANGKPLSQEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH", "length": 534 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P35503-1", "protein_name": "UDP-glucuronosyltransferase 1A3", "gene_name": "UGT1A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATGLQVPLPWLATGLLLLLSVQPWAESGKVLVVPIDGSHWLSMREVLRELHARGHQAVVLTPEVNMHIKEENFFTLTTYAISWTQDEFDRHVLGHTQLYFETEHFLKKFFRSMAMLNNMSLVYHRSCVELLHNEALIRHLNATSFDVVLTDPVNLCAAVLAKYLSIPTVFFLRNIPCDLDFKGTQCPNPSSYIPRLLTTNSDHMTFMQRVKNMLYPLALSYICHAFSAPYASLASELFQREVSVVDILSHASVWLFRGDFVMDYPRPIMPNMVFIGGINCANRKPLSQEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH", "length": 534 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P35504-1", "protein_name": "UDP-glucuronosyltransferase 1A5", "gene_name": "UGT1A5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATGLQVPLPQLATGLLLLLSVQPWAESGKVLVVPTDGSHWLSMREALRDLHARGHQVVVLTLEVNMYIKEENFFTLTTYAISWTQDEFDRLLLGHTQSFFETEHLLMKFSRRMAIMNNMSLIIHRSCVELLHNEALIRHLHATSFDVVLTDPFHLCAAVLAKYLSIPAVFFLRNIPCDLDFKGTQCPNPSSYIPRLLTTNSDHMTFLQRVKNMLYPLALSYLCHAVSAPYASLASELFQREVSVVDLVSHASVWLFRGDFVMDYPRPIMPNMVFIGGINCANGKPLSQEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH", "length": 534 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P36510-1", "protein_name": "UDP-glucuronosyltransferase 2A1", "gene_name": "Ugt2a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLKNILLWSLQLSLLGMSLGGNVLIWPMEGSHWLNVKIIIDELLRKEHNVTVLVASGALFITPSVSPSLTFEIYPVPFGKEKIESVIKDFVLTWLENRPSPSTIWTFYKEMAKVIEEFHLVSRGICDGVLKNEKLMTKLQRGKFEVLLSDPVFPCGDIVALKLGIPFIYSLRFSPASTVEKHCGKVPFPPSYVPAILSELTDQMSFADRVRNFISYRMQDYMFETLWKQWDSYYSKALGRPTTLCETMGKAEIWLMRTYWDFEFPRPYLPNFEFVGGLHCKPAKPLPKEMEEFVQTSGEHGVVVFSLGSMVKNLTEEKANLIASALAQIPQKVLWRYKGKIPATLGSNTRLFDWIPQNDLLGHPKTRAFITHGGTNGIYEAIYHGIPMVGVPMFADQPDNIAHMKAKGAAVEVNMNTMTSADLLSAVRAVINEPFYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSLDVIGFLLACMASAILLVIKCCLFVFQKIGKTXKKNKRD", "length": 527 }, "evidence": [ { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" }, { "id": "FB:FBgn0036842", "url": "https://alliancegenome.org/gene/FB:FBgn0036842#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P36511-1", "protein_name": "UDP-glucuronosyltransferase 2B15", "gene_name": "Ugt2b15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGKWISALLLLQISFCFKSGNCGKVLVWPMEYSHWMNIKIILEELVQKGHEVTVLRPSAFVFLDPKETSDLKFVTFPTSFSSHDLENFFTRFVNVWTYELPRDTCLSYFLYLQDTIDEYSDYCLTVCKEAVSNKQFMTKLQESKFDVVFSDAIGPCGELIAELLQIPFLYSLRFSPGYTIEQYIGGVLFPPSYVPMIFSGLAGQMTFIERVHNMICMLYFDFWFQTFREKKWDPFYSKTLGRPTTLAEIMGKAEMWLIRSYWDLEFPHPISPNVDYIGGLHCKPAKPLPKDIEDFVQSSGEHGVVVFSLGSMVRNMTEEKANIIAWALAQIPQKVLWRFDGKKPPTLGPNTRLYKWLPQNDLLGHPKTKAFVTHGGANGIYEAIHHGIPMIGIPLFAEQHDNIAHMVAKGAAVEVNFRTMSKSDLLNALEEVIDNPFYKKNAMWLSTIHHDQPTKPLDRAVFWIEFVMRHKGAKHLRSLGHNLPWYQYHSLDVIGFLLSCVAVTVVLALKCFLFVYRFFVKKEKKTKNE", "length": 530 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12544", "url": "https://alliancegenome.org/gene/HGNC:12544#orthology", "database": "AGR" }, { "id": "HGNC:12554", "url": "https://alliancegenome.org/gene/HGNC:12554#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P36537-1", "protein_name": "UDP-glucuronosyltransferase 2B10", "gene_name": "UGT2B10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALKWTTVLLIQLSFYFSSGSCGKVLVWAAEYSLWMNMKTILKELVQRGHEVTVLASSASILFDPNDSSTLKLEVYPTSLTKTEFENIIMQLVKRLSEIQKDTFWLPFSQEQEILWAINDIIRNFCKDVVSNKKLMKKLQESRFDIVFADAYLPCGELLAELFNIPFVYSHSFSPGYSFERHSGGFIFPPSYVPVVMSKLSDQMTFMERVKNMLYVLYFDFWFQIFNMKKWDQFYSEVLGRPTTLSETMRKADIWLMRNSWNFKFPHPFLPNVDFVGGLHCKPAKPLPKEMEEFVQSSGENGVVVFSLGSMVSNMTEERANVIATALAKIPQKVLWRFDGNKPDALGLNTRLYKWIPQNDLLGHPKTRAFITHGGANGIYEAIYHGIPMVGIPLFFDQPDNIAHMKAKGAAVRVDFNTMSSTDLLNALKTVINDPSYKENIMKLSRIQHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHNLTWFQYHSLDVIGFLLACVATVLFIITKCCLFCFWKFARKGKKGKRD", "length": 528 }, "evidence": [ { "id": "HGNC:12544", "url": "https://alliancegenome.org/gene/HGNC:12544#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "FB:FBgn0036842", "url": "https://alliancegenome.org/gene/FB:FBgn0036842#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P54855-1", "protein_name": "UDP-glucuronosyltransferase 2B15", "gene_name": "UGT2B15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLKWTSVFLLIQLSCYFSSGSCGKVLVWPTEYSHWINMKTILEELVQRGHEVTVLTSSASTLVNASKSSAIKLEVYPTSLTKNYLEDSLLKILDRWIYGVSKNTFWSYFSQLQELCWEYYDYSNKLCKDAVLNKKLMMKLQESKFDVILADALNPCGELLAELFNIPFLYSLRFSVGYTFEKNGGGFLFPPSYVPVVMSELSDQMIFMERIKNMIHMLYFDFWFQIYDLKKWDQFYSEVLGRPTTLFETMGKAEMWLIRTYWDFEFPRPFLPNVDFVGGLHCKPAKPLPKEMEEFVQSSGENGIVVFSLGSMISNMSEESANMIASALAQIPQKVLWRFDGKKPNTLGSNTRLYKWLPQNDLLGHPKTKAFITHGGTNGIYEAIYHGIPMVGIPLFADQHDNIAHMKAKGAALSVDIRTMSSRDLLNALKSVINDPVYKENVMKLSRIHHDQPMKPLDRAVFWIEFVMRHKGAKHLRVAAHNLTWIQYHSLDVIAFLLACVATVIFIITKFCLFCFRKLAKKGKKKKRD", "length": 530 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P70691-1", "protein_name": "UDP-glucuronosyltransferase 1-2", "gene_name": "Ugt1a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTGLCVPLRGISGLLLLLCALPWAEGAKVLVLPMEGSQWLSMRDVVRELHARGHQTVVLASEVTVHIKGEDFFTLKTYAFPYTKEEYQQEILSDIEKTFKTQHFVKAFFETTASIRNFFDLYSNSCIALLHNKMLIQQLNSSFFDVILTDPIFPCGAVLAKYLQIPAVFILRSLSCGIEYEATQCPNPSSYIPNLLTRLSDHMDFLQRVQNMLYYLVLKYICRLSITPYESLASELLQREVSLVEVLSHASVWLFRGDFVLDYPRPIMPNMVFIGGINCVTKKPLSQEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVFKCCAYGCRKCFGGKGRVKKSHKSKTH", "length": 533 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q62452-1", "protein_name": "UDP-glucuronosyltransferase 1A9", "gene_name": "Ugt1a9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPVAFPTSFFLCLLLASGLAQAGRLLVVPMDGSHWFTMQMVVEKLIHRGHEVVVVIPEVSWQLGKSLNCTVKTYSISHTLEDLDREFKYLSYTQWKTPEHSIRSFLTGSARGFFELTFSHCRSLFNDKKLVEYLKQRFFDAVFLDPFDVCGLIVAKYFSLPSVIFARGVFCDYLEEGAQCPSLPSYVPRLFSKYTDTMTFKERVWNHLIYIEEHAFCSYFLRTAVEVASEILQTPVTMTDLFSPVSIWLLRTDFVLEFPRPVMPNMVFIGGINCLQKKSLSKEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVFKCCAYGCRKCFGGKGRVKKSHKSKTH", "length": 528 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q62789-1", "protein_name": "UDP-glucuronosyltransferase 2B7", "gene_name": "Ugt2b7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPQKWISALLLLQISFCFRSGNCGKVLVWPLEYSHWMNLKIILDELVQRGHEVTVLRPSSSVSLDPKKASGLVYETSPTTSNNDEVEKSFYPVGDMWTYDVPKYTCLRYYPSLNKMFGQFSDLWLQLCREVVSNKELIAKLKESQFDVVLSDAVGPCGELIAEILQLPFVYSLRFATAPGIEKYSAGQPFPPSYVPIILSGFSGQMTFMERVENMLCLLYFDSWFESFPAKDWDPFFSEILGRPTTMVDTMKKAEIWLIRSYWDLEFPRPSLPNIEFVGGLHCQPAKPLPKEMEDFAQSSGEHGVWVFSLGSMIRNITQERANTIASALAQIPQKVFWRFEGKKPDTLGPNTRVFKWIPQNDLLGHPKTKAFVTHGGANGIYESIHYGIPPMVGIPLFAEQRDNVAHMVAKGAAVSIDFHTMSSSDLLNALKAVINNPSYKKKVMWLSAIHHDQPLKPLDRAVFWIEFVMRHKGAKHLRPLAHNLALVSVHSLDVIGFLLACVLAIVLLAVKCCLFLYRFFVKVAKNKRD", "length": 530 }, "evidence": [ { "id": "HGNC:12554", "url": "https://alliancegenome.org/gene/HGNC:12554#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q63886-1", "protein_name": "UDP-glucuronosyltransferase 1A1", "gene_name": "Ugt1a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTVVCWSSRLLLLLPYLLLCVFGPSASHAGRLLVFPMDGSHWLSMLGVIQQLQQKGHEVVVIAPEASIHIKEGSFYTLRKFPVPFQKENVTATLVELGRTAFNQDSFLLRVVKIYMKVKRDSSMLLAGCSHLLHNAEFMASLEESHFDALLTDPFLPCGSIVAQYLTVPTVYFLNKLPCSLDSEATQCPVPLSYVPKSLSFNSDRMNFLQRVKNVLLAVSENFMCRVVYSPYGSLATEILQKEVTVQDLLSPASIWLMRSDFVKDYPRPIMPNMVFIGGINCLQKKPLSQEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVFKCCAYGCRKCFGGKGRVKKSHKSKTH", "length": 535 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q64435-1", "protein_name": "UDP-glucuronosyltransferase 1A6", "gene_name": "Ugt1a6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MACLLPAAQTLPAGFLFLVLWASVLGDKLLVVPQDGSHWLSMKEIVEHLSERGHDIMVLVPEVNLLLGESKYYRRKIFSVTYSLEELQTRFRTFGNNHFLPGASLMGPLREYRNNMIVVDMFFSNCQSLLKDSATLSFLRENKFDALFTDPAMPCGVILAEYLNLPSVYLFRGFPCSLEHMLGQSPSPVSYVPRFYTKFSDHMTFPQRLANFIVNILENYLYYCLYSKYEIIASDLLKRDVSLPSLHQNSLWLLRYDFVFEYPRPVMPNMIFLGGINCKKKGKLTQEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVFKCCAYGCRKCFGGKGRVKKSHKSKTH", "length": 531 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q64550-1", "protein_name": "UDP-glucuronosyltransferase 1A1", "gene_name": "Ugt1a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVVCRSSCSLLLLPCLLLCVLGPSASHAGKLLVIPIDGSHWLSMLGVIQQLQQKGHEVVVIAPEASIHIKEGSFYTMRKYPVPFQNENVTAAFVELGRSVFDQDPFLLRVVKTYNKVKRDSSMLLSGCSHLLHNAEFMASLEQSHFDALLTDPFLPCGSIVAQYLSLPAVYFLNALPCSLDLEATQCPAPLSYVPKSLSSNTDRMNFLQRVKNMIIALTENFLCRVVYSPYGSLATEILQKEVTVKDLLSPASIWLMRNDFVKDYPRPIMPNMVFIGGINCLQKKALSQEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKARAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVYKSCAYGCRKCFGGKGRVKKSHKSKTH", "length": 535 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q64633-1", "protein_name": "UDP-glucuronosyltransferase 1A7", "gene_name": "Ugt1a7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPADVPASLPLGLCLLLASGFGHAGKLLVVPMDGSHWFTMQMVVEKLLPKGHEVVVVVPEVSWQLGKPLNFTVKTYSVSHTQEDLNREFKFFIDSQWKTQQESGVLPLLTSPAQGFFELLFSHCRSLFKDKKLVEYLKQSSFDAVFLDPFDVCGLTVAKYFSLPSVVFSRGIFCHYLEEGSQCPSPPSYVPRPILKLTDTMTFKERVWNLLSYMGEHAFCPSFFKTATDIASEVLQTPVTMTDLFSPVSVWLLRTDFTLELPRPVMPNVIHIGGINCHQRKPVSKEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTLLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKARAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVYKSCAYGCRKCFGGKGRVKKSHKSKTH", "length": 531 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q64634-1", "protein_name": "UDP-glucuronosyltransferase 1A8", "gene_name": "Ugt1a8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPSGCPPSLPLCVCLFLASGFAQAGRLLVVPMDGSHWFTMQMIVEKLSHRGHEVVVVIPEVSWHMGKSLNFTVKLLLVLNTLEDLNYHFKFFAHNQWKTQEVGMFSLLKHSGKGFFELLFSHCRSLFKDKKLVEYLKQSSFDAVFLDPFDVCGLILAKYFSLPSVVFSGGIFCHYLDEGAQCPSPPSYVPRILSKFTDTMTFKERVWNHLSYMKERAFCPYFFKTAVEIASEVLQTPVTMRDLFSPVSIWMFRTDFVLEFPRPMMPNMVYIGGINCHQGKPLSKEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTLLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKARAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVYKSCAYGCRKCFGGKGRVKKSHKSKTH", "length": 530 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q64637-1", "protein_name": "UDP-glucuronosyltransferase 1A3", "gene_name": "Ugt1a3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGIQGFLQKLSGLLLLLCALPWAEGGKVLVFPMEGSHWLSIRDVVRELHARGHQAVVLAPEVTVHIKEEDFFTLQTYPVPYTKEEYRHHLLGHLQNFFETEFSLKLVLQTMAAVNNVSTFYVRSCRGLLHNTALIQSLNSSSFDVVLTDPFFPCGAVLAMYLRVPAVFFLQSMLCELEFEATNSPNPSSYIPRLLTLNSDHMSFLDRVKNMLYPVPWMYLCHVNYGSLARLASDLLQREVSVVEILRHASVWLLRKDFVFHYPRPFMPNMVFIGGINCANRKPLSQEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTLLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKARAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVYKSCAYGCRKCFGGKGRVKKSHKSKTH", "length": 531 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q64638-1", "protein_name": "UDP-glucuronosyltransferase 1A5", "gene_name": "Ugt1a5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLHVTLQGLAGLLLLLYALPWAEGGKVLVFPMEGSHWLSMRDVVRELHARGHQAVVLAPEVTVHIKEEDFFTLQTYPVPYTRQGFRQQMMRNIKVVFETGNYVKTFLETSEILKNISTVLLRSCMNLLHNGSLLQHLNSSSFDMVLTDPVIPCGQVLAKYLGIPTVFFLRYIPCGIDSEATQCPKPSSYIPNLLTMLSDHMTFLQRVKNMLYPLALKYICHFSFTRYESLASELLQREVSLVEVLSHASVWLFRGDFVFDYPRPVMPNMVFIGGINCVIKKPLSQEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTLLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKARAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVYKSCAYGCRKCFGGKGRVKKSHKSKTH", "length": 531 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6PDD0-1", "protein_name": "UDP-glucuronosyltransferase 2A2", "gene_name": "Ugt2a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIKKVLQLLIFHLTLAEIVLSGNVVVWPTDGSHWLNIKILLEELVQRNHSVTVLAPSETLFINSRLDAFINFEEIPVSYTKSKIDEIIEHMIALWLDHRPTPLTMWTFYKELGNLLATFYTTNKQMCDGVLNNPTVMERLQKGGFDVLLADPVTMCGELVALKLGIPFVYTLRFSPAFTVERHCGKIPAPISYVPAALSELTDQMSFGERVKNIISYSLQDYIFKTYWGEWNSYYSKVLGRPTTLCETMGKAEIWLMRTYWDFEFPRPYLPNFEFVGGLHCKPAKPLPKEMEEFVQTSGEHGIVVFSLGSMVKNLTDEKANLIASALAQIPQKVLWRYKGKIPDTLGSNTRLFDWIPQNDLLGHPKTRAFITHGGTNGIYEAIYHGIPMVGVPMFADQPDNIAHMKAKGAAVEVNMNTMTSSDLLNALRTVINEPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSLDVIGFLLACVASAILLVAKCCLFIFQKVGKTGKKKKRD", "length": 528 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "FB:FBgn0036842", "url": "https://alliancegenome.org/gene/FB:FBgn0036842#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6UWM9-1", "protein_name": "UDP-glucuronosyltransferase 2A3", "gene_name": "UGT2A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRSDKSALVFLLLQLFCVGCGFCGKVLVWPCDMSHWLNVKVILEELIVRGHEVTVLTHSKPSLIDYRKPSALKFEVVHMPQDRTEENEIFVDLALNVLPGLSTWQSVIKLNDFFVEIRGTLKMMCESFIYNQTLMKKLQETNYDVMLIDPVIPCGDLMAELLAVPFVLTLRISVGGNMERSCGKLPAPLSYVPVPMTGLTDRMTFLERVKNSMLSVLFHFWIQDYDYHFWEEFYSKALGRPTTLCETVGKAEIWLIRTYWDFEFPQPYQPNFEFVGGLHCKPAKALPKEMENFVQSSGEDGIVVFSLGSLFQNVTEEKANIIASALAQIPQKVLWRYKGKKPSTLGANTRLYDWIPQNDLLGHPKTKAFITHGGMNGIYEAIYHGVPMVGVPIFGDQLDNIAHMKAKGAAVEINFKTMTSEDLLRALRTVITDSSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRSAAHDLTWFQHYSIDVIGFLLACVATAIFLFTKCFLFSCQKFNKTRKIEKRE", "length": 527 }, "evidence": [ { "id": "HGNC:28528", "url": "https://alliancegenome.org/gene/HGNC:28528#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "FB:FBgn0036842", "url": "https://alliancegenome.org/gene/FB:FBgn0036842#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6ZQM8-1", "protein_name": "UDP-glucuronosyltransferase 1A7", "gene_name": "Ugt1a7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPADFPASLPLCVCLLLASGLAQAGRLLVVPMDGSHWFTMQTVVEKLLHKGHEVVVVVPEVSWQLTKPLNFVVKTYAVSHTQEDLNREFKIFIDAQWKSQQEGGILPLLDSPAKGFFELLFSHCRSLFNDKKLVEYLKQTSFDAVFLDPFDVCGLTVAKYFSLPSVVFSRGIFCHYLEDAAQCPSPPSYIPRMLLKFTDTMTFKERTRNLLAYMGERAFCHKFFKSAADIASEVLQTPVTMTDLFSPVSIWLLRTDFVLEFPRPVMPNVIYIGGINCHQGKPLSKEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVFKCCAYGCRKCFGGKGRVKKSHKSKTH", "length": 531 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80X89-1", "protein_name": "UDP-glucuronosyltransferase 2A1", "gene_name": "Ugt2a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLKNILLCSLQISLLGMSLGGNVLIWPMEGSHWLNVKIIIDELLRKEHNVTVLVASGALFITPSSISPSLTFEIYPVPFGKEKIESVIKDFVLTWLENRPSPSTIWTFYKEMAKVIEEFHLVSRGICDGVLKNEKLMSKLQKEKFEVLLSDPVFPCGDIVALKLGIPFIYSLRFSPASTVEKHCGKVPFPPSYVPAILSELTDQMSFTDRVRNFISYRMQDYMFETLWKQWDSYYTKALGRPTTLCETMGKAEIWLMRTYWDFEFPRPYLPNFEFVGGLHCKPAKPLPKEMEEFVQTSGEHGIVVFSLGSMVKNLTDEKANLIASALAQIPQKVLWRYKGKIPDTLGSNTRLFDWIPQNDLLGHPKTRAFITHGGTNGIYEAIYHGIPMVGVPMFADQPDNIAHMKAKGAAVEVNMNTMTSSDLLNALRTVINEPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSLDVIGFLLACVASAILLVAKCCLFIFQKVGKTGKKKKRD", "length": 528 }, "evidence": [ { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" }, { "id": "FB:FBgn0036842", "url": "https://alliancegenome.org/gene/FB:FBgn0036842#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8BWQ1-1", "protein_name": "UDP-glucuronosyltransferase 2A3", "gene_name": "Ugt2a3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVSEKCVAAFFLLQLCWAGCGFCSKVLVWPCDMSHWLNLKTILEELGARGHEVTVLKYPSIIIDQSKRIPLHFENIPLLYEIETAENRLNEIANLAVNVIPNLSLWEAAKTLQDFFLQVTGDFESICRSVLYNQKFMDKLRDAQYDVVVIDPVVPCGELVAEVLQIPFVYTLRFSMGYYMEKHCGQLPIPLSYVPVVMSELTDNMTFTERVKNMMFSLLFEYWLQQYDFAFWDQFYSETLGRPTTFCKTVGKADIWLIRTYWDVEFPRPYLPNFEFVGGLHCKPAKPLPKEMEEFVQSSGEHGVVVFSLGSMVKNLTEEKANLIASVLAQIPQKVLWRYSGKKPATLGSNTRLFNWIPQNDLLGHPKTKAFITHGGTNGIYEAIYHGVPMVGVPMLGDQPHNIAHMEAKGAALKVSISTMTSTDLLSAVRAVINEPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSLDVIGFLLLCVVTLTFIITKFCLFVCQKLYMKESKKMGNRKKKN", "length": 534 }, "evidence": [ { "id": "HGNC:28528", "url": "https://alliancegenome.org/gene/HGNC:28528#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "FB:FBgn0036842", "url": "https://alliancegenome.org/gene/FB:FBgn0036842#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BY64-1", "protein_name": "UDP-glucuronosyltransferase 2B28", "gene_name": "UGT2B28", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALKWTSVLLLIHLGCYFSSGSCGKVLVWTGEYSHWMNMKTILKELVQRGHEVTVLASSASILFDPNDAFTLKLEVYPTSLTKTEFENIIMQQVKRWSDIQKDSFWLYFSQEQEILWEFHDIFRNFCKDVVSNKKVMKKLQESRFDIIFADAFFPCGELLAALLNIPFVYSLCFTPGYTIERHSGGLIFPPSYIPVVMSKLSDQMTFMERVKNMIYVLYFDFWFQMCDMKKWDQFYSEVLGRPTTLFETMGKADIWLMRNSWSFQFPHPFLPNIDFVGGLHCKPAKPLPKEMEEFVQSSGENGVVVFSLGSVISNMTAERANVIATALAKIPQKVLWRFDGNKPDALGLNTRLYKWIPQNDLLGLPKTRAFITHGGANGIYEAIYHGIPMVGIPLFWDQPDNIAHMKAKGAAVRLDFHTMSSTDLLNALKTVINDPSYKENVMKLSIIQHDQPVKPLHRAVFWIEFVMCHKGAKHLRVAARDLTWFQYHSLDVIGFLLACVATVIFVVTKFCLFCFWKFARKGKKGKRD", "length": 529 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9HAW7-1", "protein_name": "UDP-glucuronosyltransferase 1A7", "gene_name": "UGT1A7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARAGWTGLLPLYVCLLLTCGFAKAGKLLVVPMDGSHWFTMQSVVEKLILRGHEVVVVMPEVSWQLGRSLNCTVKTYSTSYTLEDQDREFMVFADARWTAPLRSAFSLLTSSSNGIFDLFFSNCRSLFNDRKLVEYLKESCFDAVFLDPFDACGLIVAKYFSLPSVVFARGIFCHYLEEGAQCPAPLSYVPRLLLGFSDAMTFKERVWNHIMHLEEHLFCPYFFKNVLEIASEILQTPVTAYDLYSHTSIWLLRTDFVLEYPKPVMPNMIFIGGINCHQGKPVPMEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH", "length": 530 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9HAW8-1", "protein_name": "UDP-glucuronosyltransferase 1A10", "gene_name": "UGT1A10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARAGWTSPVPLCVCLLLTCGFAEAGKLLVVPMDGSHWFTMQSVVEKLILRGHEVVVVMPEVSWQLERSLNCTVKTYSTSYTLEDQNREFMVFAHAQWKAQAQSIFSLLMSSSSGFLDLFFSHCRSLFNDRKLVEYLKESSFDAVFLDPFDTCGLIVAKYFSLPSVVFTRGIFCHHLEEGAQCPAPLSYVPNDLLGFSDAMTFKERVWNHIVHLEDHLFCQYLFRNALEIASEILQTPVTAYDLYSHTSIWLLRTDFVLDYPKPVMPNMIFIGGINCHQGKPLPMEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH", "length": 530 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9HAW9-1", "protein_name": "UDP-glucuronosyltransferase 1A8", "gene_name": "UGT1A8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARTGWTSPIPLCVSLLLTCGFAEAGKLLVVPMDGSHWFTMQSVVEKLILRGHEVVVVMPEVSWQLGKSLNCTVKTYSTSYTLEDLDREFMDFADAQWKAQVRSLFSLFLSSSNGFFNLFFSHCRSLFNDRKLVEYLKESSFDAVFLDPFDACGLIVAKYFSLPSVVFARGIACHYLEEGAQCPAPLSYVPRILLGFSDAMTFKERVRNHIMHLEEHLFCQYFSKNALEIASEILQTPVTAYDLYSHTSIWLLRTDFVLDYPKPVMPNMIFIGGINCHQGKPLPMEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH", "length": 530 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9V9X9-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt35D1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPPIFLLVCLLPGYSEGARILAVFPLPSSSHYFFALPYLKSLASLGHEITSVSPYPQREPFRNIHDIPVPEVFENFNEVLRIASTPRSTWQSSDFINEYVLNLTKTVLNNEGVRRDILGPQKPHFDLVIMDLWRMDVLSGLAAYFDAPIIGMASYGTDWKIDELMGNVSPISYLQSPSSRFYDLEAYGERLLHLMERTFSYMNYKWRHVRKQETLYSQFFPSVAERKPLSEISRNFDLVLVNQHFTLGPPRPYVPNMIQVGGLHVDHSTEALSAELDHFIQGAGESGVIYFSLGTNVKSKSLSEDRRKVLLETFASLPQRIVWKFEDELLPGKPPNVFISKWFPQQAILAHPNVKLFITHGGLLSTIESIHHGKPMLGLPCLFDQFRNMDHVRQVGLGLVLNIKQMTSEEFRSTIIRLLTNKSFEETARITAARYRDQPMKPMETAIWWTEYVLSHKGAAHMQVAGKDLGFVRYHSLDVFGTFLVGALVILGIVTYLLVMTLRKCLFLIKRGKCEAIKKIQ", "length": 521 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12544", "url": "https://alliancegenome.org/gene/HGNC:12544#orthology", "database": "AGR" }, { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "HGNC:28528", "url": "https://alliancegenome.org/gene/HGNC:28528#orthology", "database": "AGR" }, { "id": "HGNC:12554", "url": "https://alliancegenome.org/gene/HGNC:12554#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VCL3-1", "protein_name": "UDP-glycosyltransferase family 303 member B2", "gene_name": "Ugt303B2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRLGYAWLAFGLLLHLNLYLELGQAANILGVFPYRIPSPFQMVRPLIKALVERGHKVTMVTPADYPAKIDGVRHIRVPMLNQLMQNLMKNDQFFDALGDKWREGVLVSTIFYNVSHAILNNNGVQMLMRDKSIRFDMIMVEASHLDALYGLAEFYNATLLGISCMHMTWHIDYLAGNLAPSVYEPISPNGFALDNTFLSRWSNWIYITEEKLLERLVFRPAQVRLFKKFFGYPAEKLDELRARFSVILVNSHFSMGRVRANVPNIIEVAGVHLSEPPEPCGAELQKYLDEAEHGAIYFSMGQDILIKYLPENMQKQLLLVFLQMKQRVIWKSELSMLANKSENIYVMDKVPQRMVLAHPNLRLFITHGGLQSVMEAIDNGVPMLGLPLFFDQFNNIHRVQLAGMAKVLDPNDLNADTLIETIKELLENPSYAQRAKEMAASFRDRPMSPLDTAIWWTEYALRNRDTSHMRLNVEEIPLMRYYRLDSILTFGVRLGCVCGSLIFLGWRLYQKNRNRHTRLQERERVIAQIQLGLSNYEVVS", "length": 540 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VCL4-1", "protein_name": "UDP-glycosyltransferase family 303 member B1, isoform A", "gene_name": "Ugt303B1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRLRYCWLTLSLCLLLQHDRAQAANILGIFPYRHISPFFVMQPLVRTLATRGHNVTLITPIGMPNDIEGVRHIRVAQLNERIKEMLESDQVLDFMINKWTESALTAKALFNASNDILSDPGVQRMLHDKSESFDLIIMEPSSLDALYGLVEFYNATLMGLSSIRINWHTYELAGNPAPSIYEPISPVGFSLETSLFSRVYNWIHIMEEKLVNYLILRPAQLHLFQKFFGYSAQKMNELRSRFSLMLINSHYSMGKVRANAPNIIEVGGLHLSEPPEPSDEELQKFLDKADHGVIYFSMGNDILIKFLPENIQELLLQTFATLNESIIWKSELLYMPDKSDNVYVVEQAPQRHILNHPNVRLFITNGGLLSVIEAVDSGVPMLGLPMFFDQFGNMRWVQLSGMAEVMDINSLNKDTLTETIKHMLANNSYYLKAKEISQFFKDRPMSPLDTAVWWTEYALRNRNITRMRLNLEEIPLIEYYRIDSILAFSLRFGLVAASLIFLVYTLFLKYRIRLRRLHP", "length": 519 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12544", "url": "https://alliancegenome.org/gene/HGNC:12544#orthology", "database": "AGR" }, { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "HGNC:28528", "url": "https://alliancegenome.org/gene/HGNC:28528#orthology", "database": "AGR" }, { "id": "HGNC:12554", "url": "https://alliancegenome.org/gene/HGNC:12554#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VCL5-1", "protein_name": "UDP-glycosyltransferase family 303 member B3", "gene_name": "Ugt303B3", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MHLEFYWLAVLFCLFLQKDLYQDSVQAANILGIFSYHFSSHNLVVRPLAKALVKRGHNVTLITPVGMPTDIEGVRHIRVPKLNQRVQEMIEGDQILDFFGSKWIASLMVVSMLYNMSSDILSDKGVQKMLQNRNERFDLVMLEPSALEALYGVVEHYNATLMGFSGGNVNWSTEEVAGNFAPSINDPISSLGYSRSNSLLSKIYNWVHITEEKLLKHLIFRPSQLRIFKKFFNFSEQKFYNMREKYSVILVNNHISMGRVRSNVPNIIEVGGLHLTEPAEPCDSKLQKFMDDAEHGVIYFSMGQEIMVQFLPEDMQQNLMKSLDQFKQRVVWKTELYNMPNKSDNVYVIEQPPQRAVLAHPNTRLFITNGGLLSVMEAVYSGVPILGLPVFFDQFINLRNVNLRGMAEVLDANEMTLEILTSTIRKLLENPRYALKAKKMSQSFRDRPMSPLDTAVWWTEYALRNKDASHMRLNTEDVPLYYEWDWGLLLGLRFGIVFGSVIYLVYKLFQKTSARRRPFQVTGTVSQHPSLLDRRSQTQ", "length": 539 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12544", "url": "https://alliancegenome.org/gene/HGNC:12544#orthology", "database": "AGR" }, { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "HGNC:28528", "url": "https://alliancegenome.org/gene/HGNC:28528#orthology", "database": "AGR" }, { "id": "HGNC:12554", "url": "https://alliancegenome.org/gene/HGNC:12554#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VDA5-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt49B2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MILFMKLLFVCLLGTGDGARILAPFFLPVKSHFMMTDAIIRELVKRGHEVTFITPLSLAKENLGPNYREILLPKYDTWADISAMMKTKSALDMIDMSKLTHMRLAQHIGIKSTDFALAHPEVQELIYAKDKKGKFDLLLVEQFHNEGALMLGYIYEIPAITIATFAYANYFSQVFGFVNPLSYVPNVFLSCTDRMSLWERLENVVISTAEDVVREVSYYPQQDAVIRKHFSSLLPRVPTVKQLEQNISVILLNSYMPLTSPRPMSQNMISVGGLHILPPKPLPEHIKNYLDNAEHGAIYFSLGSQVRSADMPAEKLQIFLDVFASLKQRVLWKFEDDQLPNLPDNVKVEKWLPQADILAHPNVKVFIAHGGLFGMQEAVYHAVPVLGMPFYFDQDINIKAGQAAGYAIGLDYRTISKDQLKSALHALLKDPKYQANMMKASRIFRDRPLGAMDTAMYWINYVVEHRGAPHLVAAGVHLPWYQFYLLDVSAIILAITLLPLLTLYAVSRNYKSFRGIRAQKKEAKTE", "length": 526 }, "evidence": [ { "id": "HGNC:12544", "url": "https://alliancegenome.org/gene/HGNC:12544#orthology", "database": "AGR" }, { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "HGNC:12554", "url": "https://alliancegenome.org/gene/HGNC:12554#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VG29-1", "protein_name": "UDP-glycosyltransferase family 37 member A3", "gene_name": "Ugt37A3", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVLRVEKFLLLAIAIGAVMGSSQGANILGLFPSLSPSHLIIQMSAAKVLAENGHNVTVVTVLKPVVNHKNITVIQVPLSKEEAQQMSDTIGAMSKNDNSNMALSLLRMSDQMDFMIRKNAETLMNDRVRDLYLNRGNKFDLVISGYFMNDFQLGFARKVNAPVIVLATMPPNHLLNPLIGNPLEVSYAGISNPAEGSKAVTFQRRLSSYMQSLGFGVFSHLSERRNRNWYKEVYGNDPKMPEYSEMLKNTSLVFFSSHAASEGPIRPNVPSAIEIGGIQIKDKPDPLPQNIAEFLGNATDGAILLSLGSNVQGKHLNPDTVAKMFNVLSKLKERVIWKWEDQENTPGKSANILYSKWLPQDDILAHPNIKLFINHAGKGGITESQYHGKPMLSLPVFADQPRNANAMVKSGFGLTLSLLTLEEKPFQEAILEILSNPQYAERVKSFSTLYRDRPMTARESFLYWTEYVIRHHGAAHLQSPLVHMSFIAANNIDICFLIFVILVSVLVLIKFLVQFIYRRFISKPKKEKTH", "length": 530 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12544", "url": "https://alliancegenome.org/gene/HGNC:12544#orthology", "database": "AGR" }, { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "HGNC:28528", "url": "https://alliancegenome.org/gene/HGNC:28528#orthology", "database": "AGR" }, { "id": "HGNC:12554", "url": "https://alliancegenome.org/gene/HGNC:12554#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VG30-1", "protein_name": "UDP-glycosyltransferase family 37 member A2", "gene_name": "Ugt37A2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVHKSGIYLLLATAICVLGGCHGANILGVFTSLSPSHLIIQMSTAKVLAERGHNVTVITVLKPVVNHKNITVIMVPLTKEESQQMSDTIGAMSKTDNSNMILSMLRMMGQMEFMFDKMAGALKDDRVRDLYLNRDNKFDLVLSGYFMNVYQLGFAKKVKAPVIVVATMPPNQLLNPLIGNPLEIAYVPSISDSVEKGKGMSFRQRLAGYSSSFFFGIFDFVTQRRSKRLYKELFGDDPNMPEYSELVKNTSLIFFASHAPSEGPIRPNVPAAIEIGGIQVKDTPDPLPQNMAEFLGNATDGAILLSLGSNVKGSHINPDTVVKMFNVLSKLKQRVIWKWEDLEKTPGKSDNIFYSKWLPQDDILAHPNIKLFINHAGKGGITEAQYHGKPMLSLPVFGDQPGNADVMVKQGFGLTQSLLSLEEQPFKEAILEILSNPQYFDKVASFSSLYRDRPMSARESVIYWTEYVIRHHGAAHLQSPLVHMSFIAANNIDIYALIAVVLVILVLLLKLLLQFIYRKIFAKPKKEKKH", "length": 530 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VGS7-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt303A1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFSGPGIAGLLLTVLLFGLLCPKLTNAENILAVFSYTFGSSYLLITPFLRNLVQRGHQLTLISAVTIMPHIEGVHHIRVPKLDMLMKILLDFEYDTDLTKWTEAQFLSEYFYNCSKFVLEDPGVQELLRNASAKYSLIILEASHNDALYGFSQHFNAPLLGVAAYGSSWNIDFLVGNSAPSVYEPMSALGYTSGLNLIEKWHNLIYITEERLVERFIYLPRQIDLYKQHFPGATTSIHDLRRRFSLVLINQHFTMGRVRSNVPNIVEVAGMHLDEKPYPLDAELKKILDEAEHGVIYFSMGLQLLDHWLPPGMRASMSDAFAQLKQQVIWKTDYPEMVNQSRNVFARTWFPQRAILNHPNVKLFITHAGLLSLIESVHYAVPLLCIPLFYDQFQNTKRMEKLGVARKLDFKNLFRDEIVLAIEDLVYNASYKRNARDLSQRFHDQPMSAMDTAIWWTEYILRHKGADHMRIAEQEMSLMQYYNVDVVSVLFGRIGLSAIIVIFLGWKLVSLATRHLEYRLNVPMVR", "length": 526 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12544", "url": "https://alliancegenome.org/gene/HGNC:12544#orthology", "database": "AGR" }, { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "HGNC:28528", "url": "https://alliancegenome.org/gene/HGNC:28528#orthology", "database": "AGR" }, { "id": "HGNC:12554", "url": "https://alliancegenome.org/gene/HGNC:12554#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VGS8-1", "protein_name": "UDP-glycosyltransferase family 304 member A1", "gene_name": "Ugt304A1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFPPGRWLLPMFWLISNSICWIRSSRILVIAPFESHSQCMLVTPYIQALKDRGHQLTVIHAYKHCMHKIEDVTFIRIWYNNNVFLEFEESVGIASANNKWEEISSMSSLMANATLNVLNNVEVRALMKSRITFDAVVLEAGYSDVLYGMAAHFSAQLIGICTCVADWNINNLVGFSTSTLTEPIMPFRAKYVKNVWDRIYNWLYTTEEWLLINLVFLPKQRLIHDHFFGHLEKSFHEIRQDFALMLLNQHFSLFRARPNVPGMVEVAGLHIPKEDPQLPSDLQVFIDEAEHGVILFSLGLEQDSKDLPRKTQEILVETFKSVPQRVIWKFDGESTMSLGTDIYHSKLLPQQAILAHPNVKLFISHCGMMSVIEAAYYAKPVLGLPSFFDQFRNLEIMKEEGVALELNINSLTVKELKDAIHSMINEPEYRESALAISQRFRDQPIHPLDAAIYWTEYIIRYKGADHMKISQSQLKLFDYYSLDNFIMVGSRLSLVVALVFLVLSKSRRWLNHLSTSAKSFLPTKHLIRS", "length": 529 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12544", "url": "https://alliancegenome.org/gene/HGNC:12544#orthology", "database": "AGR" }, { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "HGNC:28528", "url": "https://alliancegenome.org/gene/HGNC:28528#orthology", "database": "AGR" }, { "id": "HGNC:12554", "url": "https://alliancegenome.org/gene/HGNC:12554#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VGS9-1", "protein_name": "UDP-glycosyltransferase family 35 member A1", "gene_name": "Ugt35A1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGGIFSVTGLGILLIGLIWLFAANADEGVQSSRILAVFPFPGRSQYIFAEQFMKELAHRGHNVTVINTFGSDKNEPNFRVIGAKKIHEIMAAFGNADYTQTASQWQMLTMTTQFLNLLTTSILDDAAVKDLLNSGEKFDLVIMEAVQTEALFGLIQHFGAETIGISSYGTDTHIDELMGNISPLSYNPLLLSSRTEQMDFKDRVMNVFEASVMWLHKRIVHLPSQRDLYAKYFPTARKSLDEVLDSFALMLLGQHFSLSYPRPYLPNMIEVGGLHLQQKRKVQPLAKELSEFVEQSEKGVIYFSMGSNIKSKDLPPSTRKMLMQTFASVPQRVLWKFEDDQLPEKPDNVFISKWFPQPDILAHPNVKLFITHGGLLSTIESIYFGKPILGLPIFYDQHLNVQRAKQVGYGLSADIWSVNATELTPLIQELLSNPSYAAAAQTKSKLFRDQKETALERAIWWTEYVLRHKGAKHLRCASRDLDFIQFHGLDTWGLLIAITFVSLLIVVILIKCLQRVFVSLISKIRKNRAEASKLKTQ", "length": 537 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12544", "url": "https://alliancegenome.org/gene/HGNC:12544#orthology", "database": "AGR" }, { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "HGNC:28528", "url": "https://alliancegenome.org/gene/HGNC:28528#orthology", "database": "AGR" }, { "id": "HGNC:12554", "url": "https://alliancegenome.org/gene/HGNC:12554#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VGT0-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt35B1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLALRIGFLLLTLPASMQAARILAIFPFPGPSQYINVVPYLKELANRGHQVTSVNAFPQKKPVVNFRDVFIPDVFNNYKELINELSGPMNLWQENNFINKFFVSVTRCVLTNKEVTETLLPPGKDHFDLIIVEALRSDAYYGFAAHFNAPIIGISTFGTDWNIDALVGNESPLSYTPLATGGLTDRMTFLERLSNFVDTTVAWLNYRFVHMSEQEKMYAKYFPEASKRVQLTDLNRNFSLVLLNQHFSLSFPRPYVPNMIEVGGLHISHKPAPLPKDLEEFIQGSGEHGVIYFSLGSNVLSKDLPADRKDLILKTFASLPQRVLWKFEDDKLPGKPSNVFISKWFPQPDILAHPKVKLFITHGGLLSTIESIHHGKPVLGLPFFYDQFLNVRRATQAGFGLGLDHTTMTQQELKETIEILLKEPRFAQIARQMSERYRDQPMSPLDTAIWWTEYVLRHKGAYHMRVAGQDLGFFAYHSLDVIGVLLGGALLLVAIIVGVLGKLTDFGNAKKKLKSK", "length": 516 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12544", "url": "https://alliancegenome.org/gene/HGNC:12544#orthology", "database": "AGR" }, { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "HGNC:28528", "url": "https://alliancegenome.org/gene/HGNC:28528#orthology", "database": "AGR" }, { "id": "HGNC:12554", "url": "https://alliancegenome.org/gene/HGNC:12554#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VGT1-1", "protein_name": "UDP-glycosyltransferase family 35 member E2", "gene_name": "Ugt35E2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPMSMLVLRLIVLVVALLPVLLEGARILGVFPIPSHSHYYHALPYLKKLASLGHEITSVSPFPLKEPVANIHDIPVPELFDNIEEIVGNLTNRKGTWNEFEYINQYTLGLVEKVLENDGVRREILQPESLQFDLIIVDLWRLDALYGLAAYFDAPIIGIASYGTDWKIDELVGNVSPLAYLQSPSFNWFDLDTYGGRLGHFVDQSMAWINWHWRHEERHEAVYRKYFPKIADKRSLSEITRNFALILVNQHFTMAPPRPYVPNIIEVGGMHVDQQPKALPQDLEDFIQGAGEHGVIYFSLGTNVRSRNLSKDRRKILIDTFASLPQRILWKFDADELSDVPSNVLISPWFPQQDILAHPNVKLFITHGGLQSTVECIHRGVPMLGLPFFYDQFRNMEHIKAQGIGLVLNYRDMTSDEFKDTIHQLLTEKSFGVKAKRTADRYRDQPMNPLDTAIWWTHYVLRHKGAPHMRVAGRNLDFITYHSLDVLGTFLLAVWAILSIVVLCAIKLLRAILKSKKGNISPKQKIN", "length": 527 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12544", "url": "https://alliancegenome.org/gene/HGNC:12544#orthology", "database": "AGR" }, { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "HGNC:28528", "url": "https://alliancegenome.org/gene/HGNC:28528#orthology", "database": "AGR" }, { "id": "HGNC:12554", "url": "https://alliancegenome.org/gene/HGNC:12554#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VGT2-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt35E1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLASGLFYLIILLFPGFLYGARILALFPVPSHSHYYHALPYLKNLASLGHEITSVSPFPSEEPVKNIYDIYVPEVLNSFDELLKQMTTPKNTWEFFDATNEFVYNITKDVFNNDGVRREILRPGKAQFDLIIVDIWKYDAFYSLAAYFEAPIIGLAPCGIDWKIDEMVGNPSPMSYLQSPSSYLYNLDTFGGRVAHVVEVAISWFNWHWRYEQKHEALYKKYFPKIAETKPLSEISQDIALVLVNQHFTLGPPRPYVPNVIEVGGMHIDEQPKALAQDLEDFIQGSGEHGVIYFSLGTNVRTKNMVDDRKRILIEAFGSLPQRVLWKFEDEELQDIPSNVLVRKWLPQQDLLAHPKVKLFITHGGMQSTIESIHYGKPMLGLPFFYDQFTNVDHIKKHGFCLSLNYHDMTSDELKATILQLLTEKRFEVTARIAGARYRDQPMKPLETAVWWTHYVLRHKGAPHMRVAGRKLSFFTHHSLDVLGTVLLVILLVIIAILLIIVFSVCKISKNISTRLVVKKQRKQKVR", "length": 527 }, "evidence": [ { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "HGNC:28528", "url": "https://alliancegenome.org/gene/HGNC:28528#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VGT3-1", "protein_name": "UDP-glycosyltransferase family 302 member C1", "gene_name": "Ugt302C1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKPTAGQTGFLALLLFCLLSCVSAYNYLVVLHTAARSHYHVGSALAKGLAAAGHQVTIISPFELKKPIKNIKDVPAKSILTSMQGRIANLLQSSKEPIIKQIINFHEMGIEITELLLKEPSVIELMKSNQTFDAVISEVFLNEAHFGFAEHFKAPLIGLGTFGAISWNTDLVGSPSPPSYVPSALLKFSDRMSLVERVGNQAFLTYEYIFLNYFYLPRQEVLYRKYFPNNKQDFYDMRKNTALVLLNQHVSLSFPRPYSPNMIEVGGMHINRKRQPLPKDILEFIEGAEHGVIYFSMGSNLKSKTLPLEKRQALIDTFAQLKQRVLWKFEDTDLPGKPANVFISDWFPQDDILAHDNVLAFITHGGLLSTTESIYHRKPFVGIPIFGDQFLNMARAEQNGYGVTVHYEELSSAKLLAAIQKIINNPEATQRVRDMSDRYRDQQQTPLERAVYWVEHVSRHKGAKYLRSASQDLNFIQYHNLDAMLILYGGIIFVLYCIFLLIRLVWRLLQELFIKKDTSKPKQKAKRN", "length": 528 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VGT4-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt302E1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRWLLNSWLLLILALFGQSWGYSYLMISHTASKSHYAVCFALAKGLAAAGHEVTLVSPFPQRKPIKNIIDVETPNIITVMGVYKARILENAKKPVLLRYPRISLMGLDITESLLKEPKVQELLKQNRTFDGVICETFMNDAHYGFAEHFGAPLITLSSLGATGWTSDLVGTPSPPSYVPHSLLRFGDRMNFWERAQNLGFQIYEFAYENLINLPRHEALYRKYFPNNKQDFYRMRKDTSLVLLNNHVSISNPRPYSPNMIEVGGMHVNRKAPKPLPQNIRKFIEEAEHGVIYFSLGSNLNSKDLPENKRKAIVETLRGLKYRVIWKYEEETFVDKPDNVLISNWLPQDDILAHEKVIAFITHGGLLSTMESIYHGKPVVGIPFFGDQFMNMARAEQMGYGITVKYAQLTASLFRSAIERITSDPSFTERVKVISSQYRDQKETPLERAVYWVEHVTRHKGAKYLRSACQDLNFIQYHNLDVLATFFSVIGLTVIFVFLLVRFLVTIVNGFLYKPSSKLKIN", "length": 521 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12544", "url": "https://alliancegenome.org/gene/HGNC:12544#orthology", "database": "AGR" }, { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "HGNC:28528", "url": "https://alliancegenome.org/gene/HGNC:28528#orthology", "database": "AGR" }, { "id": "HGNC:12554", "url": "https://alliancegenome.org/gene/HGNC:12554#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VGT5-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt302K1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRTFTLILGLLCSLGYSSGYNYLMVLNSAGRSHFNVGHALAKGLVKAGHTITVVSVFPQKKPIPGYTDVSVPNVIEVMGGDIGALWASIQKTYTQNLIDHYQMGFRITRGLFEDSNFQDFLKSNQSFDAIICETFYNDAHYGLAEHFNAPLIGLATGGGLTFITDMVGSPAPASFVPHIMLPFNDHMSLYERLLNVAFLGYERVLLDYYFLPTQEKLYKEFFPGNKRCFYKMRRNASLVLINQHVSLSFPRPHSPNMIEVGGMHIDGKWNPLPEKIERFINESEHGAIYFSMGSNLKTKDLPPSKVQEILKALGGLKQRVLWKFELDNLPNKPENVYISDWFPQTDILAHPKIMAFVTHGGMLSTTESIYHAKPVIGLPIFSDQFFNMAHAEQNGYGIMLDFKTLNAVEFRKAIERITSEPSYTKVVQGISFRYRDQQQTPIENAIYWVEHVTRHQGAAYLKSAAQRLNWWQYHNVDVLLIIFVVMVLLLIVLPITIYKLLKKLLLKGERTQSTKVKRN", "length": 519 }, "evidence": [ { "id": "HGNC:12544", "url": "https://alliancegenome.org/gene/HGNC:12544#orthology", "database": "AGR" }, { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "HGNC:12554", "url": "https://alliancegenome.org/gene/HGNC:12554#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VGT8-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt35C1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRLLTVIAIVFCALSAKPLESESAKILATLPFPGRSQYIFVESYLKALAAKGHQVTVINAFKNKETPNMRFIEALKAHEFADEMMSLLNVPLLWQQLNAMDYILNKFIDVTMEDEGVQRLLNSGETFDLVLAEMLHMEPMYAFAQHFNATLVGFSSFGTDRTIDEAAGNISPISYNPLVTSPRTDRMTFLERLENHYEVIVEDIHRHFVHLPHMRNVYKKYFPNAKKTLEEVMDSFSLILLGQHFSLSYPRPYLPNMIEVGGMHISHKPKPLPEDIKQFIEGSPHGVIYFSMGSNVKSKDLPQETRDTLLKTFAKLKQRVLWKFEDDDMPGKPANVLIKKWYPQPDILAHPNVKLFISHGGLLSSTESVYFGKPILGLPCFYDQHMNVQRAQRVGFGLGLDLNNLKQEDLEKAIQTLLTDPSYAKASLAISERYRDQPQSAVDRAVWWTEYVIRHNGAPHLRATSRDLNFIQLNSLDTLAVILAVPLLLALLIVTLSCKLLGGKKQKCLHADKLKKH", "length": 517 }, "evidence": [ { "id": "HGNC:12544", "url": "https://alliancegenome.org/gene/HGNC:12544#orthology", "database": "AGR" }, { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "HGNC:12554", "url": "https://alliancegenome.org/gene/HGNC:12554#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VIM9-1", "protein_name": "UDP-glycosyltransferase family 37 member A1", "gene_name": "Ugt37A1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVGRTKSYFVIVLALTLLIYGAQGANILGLFPSLSPSHLIISMSVAKILAEQGHNVTVVTVLEPTITHKNINLVTVPMTKEEIKQRSETIGAKQKNTSSNRFISILNMSGQMDSMLRKMADVLKDQRVKELYLNKDNHFDLVISGYFMNDYQLGFARKVNAPVVVLAPSPPSQMLNSLIGNPHDKVEKEKGMTFGQRLDSYISSLLYGIFLRQIDQRNRQYYNEIFGDDPTMPEYTDILRNTSLVFFCSHAASEGPIRPSVPAAIEIGGIQIKDKPDPLPKNLEKFLGNATHGAILLSLGSNVQGSHIKADTVKKIFSVLSNLKQRVIWKWDDLDKTPGKSDNILYSRWLPQDDILAHPSVKLFINHAGKGGISEAQYHGKPMLSLPVFGDQPGNAHAMVKSGFGLTLSLLTLEEEPFRAAVLEILSNPKYSQRVVKFSSLYRDRPASARESLIFWTEYVIRHHGAAHLQSPLVHMDFIAANNLDIYALIGAISIGLLLMLKKVVQITCRRLRTKLNKVKKQ", "length": 522 }, "evidence": [ { "id": "HGNC:28528", "url": "https://alliancegenome.org/gene/HGNC:28528#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VJ45-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt36E1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MCGCWKVFCLLALLSLVAFSDSLRILGLFPHPAISHFKFFHPIMRGLAEAGHSVDVISPFEDKDPPNGYKDHLLPPSTLTDTISLEDFERPYSFLFHYVEFFILHKMGREDCNTTLHSRALTEILKNPPGYYDVILLEQFNTDCAMSVAHVFQAPVIGMSSCALMPWHYERFGAPLIPSYISALFQGQSQEMSFAGRLGNWITVHSLNLLYKMFTVPAGNALIRQRFGPGLPSTEDLVRNTSLMLVNQHFSLSGPKPLPPNVIEVGGVHISPPKPLPSDLQKILDNAPKGVILISWGSQLKACSLSAARRDGIVKAIGRLEQEVIWKYENDTLPNKPPNLHIRKWLPQRDILAHPNLKVFMSHGGLMGTTEAVSSAVPIVGVPIYGDQSLNIAALVQRGMALQLELKKLDENTVYEALTKALDPSFKARAKEVASSYNNRIQGPLETAIWWVEHVAETKGAPLTQPSAVHLSRFVYYSLDVYSVVALSLLLPVITLLGLIRMFKRREPKGDRKLKRK", "length": 517 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12544", "url": "https://alliancegenome.org/gene/HGNC:12544#orthology", "database": "AGR" }, { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "HGNC:28528", "url": "https://alliancegenome.org/gene/HGNC:28528#orthology", "database": "AGR" }, { "id": "HGNC:12554", "url": "https://alliancegenome.org/gene/HGNC:12554#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VJ46-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt36D1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MWSPRVALLFLALALSQPDELVEAAGPLKVLGLFPHPGVSHFHFFHPIMKGLAEAGHDVSVVSHFPDKHPVAHYKDFPLTGMDKLTNSVDLKFFEKRTFYSHFQEFFLLYDWGKQTCNLTLRSEALQQILRRPGRFDVIIMEQFNTDCMMGVAHQLQAPVIALSSCVMMPWHYERMGAPLIPSHIPALFMAQSQHMNFGGRLANWFSTHALNWMYKLLSVPAADAMVQYKFGHDVPSVGELVKNTSMFFVNQHYSLSGPKVTPPNVIELGGIHIQKSKPLPADLQRILDNAEEGVILISWGSMIRANSLSAAKRDGIIRAVARLKQKVIWKWENETLPNQPPNMHIMKWLPQRDILCHPNVKVFMSHGGLMGTSEAAYCGVPVVATPMYGDQFVNTAALVERGMGTILNFEDIGENTVMRALKKALDKKFHDAAKVVSHSFHHRPQQALHTAIWWVEHVAHTGGAPLLKPSAVEMSRFVYYSLDVYAVLALVLGSIIASWVWLLRLCCGSSAAQKTKKD", "length": 519 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12544", "url": "https://alliancegenome.org/gene/HGNC:12544#orthology", "database": "AGR" }, { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "HGNC:28528", "url": "https://alliancegenome.org/gene/HGNC:28528#orthology", "database": "AGR" }, { "id": "HGNC:12554", "url": "https://alliancegenome.org/gene/HGNC:12554#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VJ47-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt36F1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKLLPLALLAFLLRPKPNDAAHILGLFQHPGKSHFDFFRPMFLALAERGHNISMYSYFPLEKPVANYTDYVFQGMPLLTDIVDLSNFESEWKPLGLPFKVPTYFMLHDWGLRSCKVALNSPLITQLLKSPIRYDVILLEHFSNDCMAAVAHLLNAPVIALSSCAIMPWHYKRMGSPFINPIMPMNFLPYTDEMSLIDRLNNFFHFHTVNTLYNMITQPATDALIAERFGPGLPPINEIVKNTSLMLINQHYALTGPRPYAPNVIEVGGLQVGPIKPLPQHLLDLLDRSPNGVIYISWGSMVNSNTLPSGKRSALFQSISQLKEYNFVMRWKSLESLEDKQPSNLYTFDWLPQRDLLCHPKIRAFISHGGLLGTTEAIHCGVPMLVTPFYGDQFLNSGAVKQRGFGVIVDFRDFDSNHITRGLRIILDKKFAERVRRSSEAFRQRPIPPIKLATWWIEHVIKYGGAPHIQSEARHINWIVYNSIDVLLFWLGILFLLIVALRKLIKIFKTAFCRGKISRDTKTKTQ", "length": 525 }, "evidence": [ { "id": "HGNC:12544", "url": "https://alliancegenome.org/gene/HGNC:12544#orthology", "database": "AGR" }, { "id": "HGNC:12554", "url": "https://alliancegenome.org/gene/HGNC:12554#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VJ81-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt301D1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEMQLQWKCWMLIFLIGLLEFGAGSRILFMGPFPAPSHWLWLEHFQNDLLRQGHHVTSVNNHPTKHPHENLTEIIISPSFDIPKHFPKENIFSMQFVSDFNNLELWWTIGLMTTEHAFKDPKVKKLIESKDDHYDLVIIEQFFHEAFLMFGKRFNCPVVTIGTMGYADNIDHAMGILTPWSLIPHLLLSHTDRMTFGQRAYNAYLSLYDAVMRRWVYLPKMQKLAEKYFQGSIEGPLPNVLDLERNISLVLINAHRSIDLPRPSMPGLIDVGGAHIQKPKQLPTDLQNFLDNATYGVIYFSMGSYVKSTDLPQEKTALILKAFGQLKQQVIWKFENDSIGDLPSNVMIKKWMPQNDILAHPNVKLFITHGGIFGTQEGIYWGVPMLCVPLYGDQHRNTIKSVREGYARSLVFSKLTTDDLVRNIETLINDPQYKRSALEVSQRFRDNPIHPLDEATFWIEYIIRHRGARHLKSHGAFIPLHQYLLLDVLGCLLLGAFLAIWLPWRMIRRVHKWWLKGESSNKLNEGKKRL", "length": 530 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12544", "url": "https://alliancegenome.org/gene/HGNC:12544#orthology", "database": "AGR" }, { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "HGNC:28528", "url": "https://alliancegenome.org/gene/HGNC:28528#orthology", "database": "AGR" }, { "id": "HGNC:12554", "url": "https://alliancegenome.org/gene/HGNC:12554#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VJH8-1", "protein_name": "UDP-glycosyltransferase family 37 member D1, isoform C", "gene_name": "Ugt37D1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTQNRSTWIGCSLGGLLVALLALQTMPQGTEGANILGVFTSHSPSHFIVHMSIMKTLAEKGHNVTVVSSVPPKVTHKSINHIVVPMSAEDEKVLNDGMAGMVKEKPSIWNTMKSIFSSLALLIDKQVDVLEDPRFQELYLNKGNKFDVVFVGFFFNTYQVALGARFNCPVIISWSGPPMMMVNEVLGNPELSSVPQMHISAPPGQPMNFQQRMQNFASTLGFNALNIFLNHKYNKFYDRLWSKDKSMPTFAQAKRNVSLAFCNGHGISEGPIRPNVPGVIEIGGIQVKSKPDPLPEDIQEFLEKGKHGAILFSLGSNLKGEHIQPEVVKTIFKGLSSLKQQVIWKWEDPKNTPGKSANILYKKWLPQDDILAHPKLKLFITHAGKGGVAEAQYHGVPMLALPVFADQPGNADKLVASGYGLQLPLATLDVDEFKAAIKEVIENPKYAKTLKSFSQLYRDRPLSPQESVVYWTEYVIRHHGAAHMQSPLVHMNFIASNNLDIYIIAALVLYIVFIINKIVWKFVWRKLFGKSNKVSKGKKVKKQ", "length": 543 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12544", "url": "https://alliancegenome.org/gene/HGNC:12544#orthology", "database": "AGR" }, { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "HGNC:28528", "url": "https://alliancegenome.org/gene/HGNC:28528#orthology", "database": "AGR" }, { "id": "HGNC:12554", "url": "https://alliancegenome.org/gene/HGNC:12554#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VJH9-1", "protein_name": "UDP-glycosyltransferase family 37 member E1", "gene_name": "Ugt37E1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MIEYTKIGFLIAFLLSTMTQSSGGANILGVFGTHSPSHVIVHMAVMKALADRGHNITVVTQMKPKLATHENITVIIAPPTEERQRYIKEYMAEVSNEKPSFWETMVKAIVQSSNQLEGQYEFMTHPNVKEIYENPKIKFDLVFLGLMANTYQLGIAAKLKCPVIISWVGIPLPFMDTIVGNVNDPSYVPTVNVALNAGQKTMDFGLRFVNFFKYAIMCVFETVLDYKMNQFYERAFANELEFPNYHEMKRRVSLLFYNYHSASEGPIRPTVPQSIEIGGIQVKEQADPLPKELAKFLDKADEGAIFFSLGTNVNTNTFRPDTVDILYKVLSKLPQRVIWKWEDLKNKPGNASNIFFGNWLPQDDILAHPNTKLFITHAGKGGVAEAQYHGVPMVALPIFGDQQGNAEIMTKSGFGRWLDILTMTEHELEQTIREVLGNPAYRETIGKFSTLYRDRPLTARQSVIYWTEYVLRHQGALHLQSPLIHTKFVARNNLDVYGVVLLVSLLLIVTIKFLFRKILNVAIGYGSQRKAVANKLKNN", "length": 539 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12544", "url": "https://alliancegenome.org/gene/HGNC:12544#orthology", "database": "AGR" }, { "id": "HGNC:12554", "url": "https://alliancegenome.org/gene/HGNC:12554#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VJI0-1", "protein_name": "UDP-glycosyltransferase family 37 member C2, isoform B", "gene_name": "Ugt37C2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MIGVHFVFLLLLGVVASTQGANILGLFSSHSPSHLIIHMSVAKALVKAGHNVTVVSMLKPKVTHKDIHLIVVPMKEEQERIMEDQMTEMAGQKNSLVSTMYRLLTSMDVMINAQAELLSDPRFQRIYETKFDLMILGYFINDFQLGVAHKLKVPVIINWMSAPVPAIDKYTGNPSELSYVPLMGTVATQPMGFLKRTENALKSLLFEFIFVVFDYKLTRIYNDVFPEQDMPTLKELRKNISMAFVGSHLISEGPIRPLVPALIEIGGIQVKDKPDPLPKDIDQFISNAKQGAVFLSLGSNVKSSTVRPEIVQIIFKVLSELKENVIWKWEDLENTPGNSSNILYKNWLPQDDILAHPNTKLFITHAGKGGITEAQYHGVPMVALPIFGDQPGNAALMEKSGYGLALDLLSITEDSLRDALKEVLENQKYKQAIGQFSTLYRDRPMTAKQSVVFWTEYILRHQGAPNLQSPSVHMNFIQLNNLDIYALIVTILVLFVLLTRLVAKIVWNKFGGKAKISQTKKKQ", "length": 523 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VMG1-1", "protein_name": "UDP-glycosyltransferase family 37 member B1", "gene_name": "Ugt37B1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGGISRCLALQIVVLIAGAHGANILGLFTSLSPSHLVIQMSMARILAERGHNVTVVTILKPPSLHKDINHILVPMEEDILQAFNSVVGGMTKTDNSNAYVSMFRSVRQLSETFSKMGDVMKQPLVKDLYEHPDNKFDLVMVGYFMNCYQLALAHKLKVPLVVALSNPPSFLGYLLGNPWEVSYVPGMSVSIKGGKPLGFGHRVLNLLGSMAQRLFMFIIELRNARIYREIYGDDPTLPSYEDLHKNISLIFFASHGISEGPIRPNVPAVIEIGGIQVKEQPERLPQNMEQFLSEAPNGAILLSLGSNLKEDHLKSSTVQKMFNVLSKLQQKVIWKWDDLDNIPGESENILYSKWVPQVDVLAHPNITLFITHAGKGGLTEAQYHGKPMLALPVFGDQPSNADVMVMHGFGIKQSILTLEEDSFLQGIREVLDNPKYATAVKSFSTLYRDRPLSPRETLIYWVEYVIRYHGAPHIQSPVVHMSYIAANNLDVYAVILGTIVALCFITKLLFGLVVGKLRKNSRKAKVNQKHKLKKKQS", "length": 537 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VQT0-1", "protein_name": "UDP-glycosyltransferase family 36 member A1, isoform A", "gene_name": "Ugt36A1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTTCLRSGVLIIVLLGILGIPEPISAGNILAVYPHFGFSHFKVVMPILNELAHRGHDITVISYVKNPQAGAYPNYEELLISAPGEDQSSTTINLVPLTEHTPTRSLGVLIREYVDLHEEGQKTCEHLFASGHIERAIERHRNKPYDLLLTEYFNSDCQLALAKLLNLPIIGLSTCALMPYYYDRIDLPDTPAFIQSEFVGFAGQLNWHERLLNFVQAKLLKFLYKYHSNRADNELVRKYLGVEVDVEEVARTQTAFIFGNQHYSLMGSRPQSLQFVEIGGVHITKKAEQELPQNIANFLNQSAEGVIFISWGSMVRASSIDEDKLSAILEVLKSQPLKIIWKWEADETPDTDASKFLFVKWAPQLALLCHPKVKLFWSHGGLLGTTESVHCGKPLLVTPIYGDQFLNAFSVQNRGMGLKLDYQDITVPNLKKALAELSKNSYAQRSLEVSKVFNERQQTPLESAIWSVEHVISNGLIAARLLQSPGIELNGFVYHSLDSVALILLPLILLILVLCYLCKRNPSKLAHKKVGKKPKRS", "length": 537 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12544", "url": "https://alliancegenome.org/gene/HGNC:12544#orthology", "database": "AGR" }, { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "HGNC:28528", "url": "https://alliancegenome.org/gene/HGNC:28528#orthology", "database": "AGR" }, { "id": "HGNC:12554", "url": "https://alliancegenome.org/gene/HGNC:12554#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080227-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080227-7#orthology", "database": "AGR" }, { "id": "MGI:3576095", "url": "https://alliancegenome.org/gene/MGI:3576095#orthology", "database": "AGR" }, { "id": "MGI:2149905", "url": "https://alliancegenome.org/gene/MGI:2149905#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W2J3-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt49C1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MQFPLLFGLLLTGTLYSQLELAEGSKILAVYAFPGKSHFMMHTALIRELVESGHQVTMVTAFSLEKEQLGSNYTEILIEPVYDFWHDVKLNFGAQHLFELTRMTNYDFLKMLEIIGLKTTEHALRQPKVRSLIHAEQKEGVFDLLLAEQFYQEAFLALAHLYKIPVVTTSTLGYENHMSQMMGLITPWSFVPHGFMPFTDRMSFLERVKNSYASFYEDMDRLLNYFPKMDAVAREFFGPVLTEVPKVKHMERQISVMLLNSHAPLTTARPTVDAMVPVGGMHIYPPKPLPADMQALLDGATEGAIFFSLGSNVQSKDMPVEMLRLFLQVFGSLKQRVLWKFEDESISQLPDNVMVRKWLPQADILAHRHVKVFITHGGLFGTQEGVHYAVPMLGIPFYCDQHLNMNKAVLGGYAISLHFQSITEEILRHSLDQLIHNVTYKENVQRVSDIFRDRPLEPRKSAVYWIEYVIRHRGASHMRSAGLDLNWFQFYLLDVIAFVAIIALAGVMALSLAIRLLMGSNKKHRKAKQN", "length": 530 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W2J4-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt49B1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSLKSALHIFLLSLVALQQLELGTGSRILAAFFFPGKSHFMMTNAIIRELVKQGHEVTFITPFSLAKEKLGSNYKEIVIPQYDFWPEIKEMTNKNTVLEMTDLPTFAFLRMVNVMGIHTTDFALEQPEIQAVINEKNKIGKYDLLLAEQFFNEGALILGHLYQIPTITISTFGNANHLSQLFGVVSPWSYVPHAYMPYTDRMTLWERIGNVAMSAAEDLVREFSYYPGQDAVLKKHFSKLLDRVPTIKELERNISAILLNSYMPLASSRPMAYNMIPVGGLHIQPPKALPEHLQKFLDGATHGAIYFSLGSQVRSADLPPEKLKVFLEVFGSLKQRVLWKFEDESLPNLPANVKVQSWLPQGDILAHPNVKVFIAHGGLFGTQEAVYNGVPILGMPVYCDQHQNINQGKSAEYALGLDYRKVTVEELRGLLMELIENPKYRNNIKKASRIFRDRPLGAMDTAIYWINYVIEHRGAPHLVAAGVHLPWYQFYLLDIVGLGLAVILLPIVVLILICRRSSKPKSTPTKKKTKKN", "length": 532 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "MGI:1919344", "url": "https://alliancegenome.org/gene/MGI:1919344#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "UDP-glycosyltransferase activity", "id": "GO:0008194", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008194", "evidence": [ { "database": "UniProtKB", "id": "Q9VVW2", "url": "https://www.uniprot.org/uniprotkb/Q9VVW2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9VVW2", "url": "https://www.uniprot.org/uniprotkb/Q9VVW2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 245, "end_pos": 247, "annotation": "n_glycosylation_sequon" }, { "start_pos": 435, "end_pos": 437, "annotation": "n_glycosylation_sequon" }, { "start_pos": 49, "end_pos": 51, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 164, 414 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 245, "end_pos": 247 }, { "start_pos": 435, "end_pos": 437 }, { "start_pos": 49, "end_pos": 51 } ] }, "class_list": [ "glycogene", "glycosyltransferase" ], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VVX4-1", "uniprot_ac": "Q9VVX4", "uniprot_id": "Q9VVX4_DROME", "mass": { "chemical_mass": 22613.0, "monoisotopic_mass": 22613.0 }, "refseq": { "ac": "NP_001262039", "name": "mitochondrial ribosomal protein L21, isoform B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262039" }, "gene_names": [ { "name": "mRpL21", "type": "recommended", "evidence": [ { "id": "Q9VVX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVX4" } ] }, { "name": "CG9730", "type": "synonym", "evidence": [ { "id": "NP_001262039", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262039" }, { "id": "Q9VVX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVX4" } ] }, { "name": "Dmel\\CG9730", "type": "synonym", "evidence": [ { "id": "NP_001262039", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262039" }, { "id": "Q9VVX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVX4" } ] }, { "name": "Dmel_CG9730", "type": "synonym", "evidence": [ { "id": "Q9VVX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVX4" } ] }, { "name": "MRP-L21", "type": "synonym", "evidence": [ { "id": "NP_001262039", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262039" }, { "id": "Q9VVX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVX4" } ] }, { "name": "mRpL21", "type": "synonym", "evidence": [ { "id": "NP_001262039", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262039" } ] } ], "protein_names": [ { "name": "Large ribosomal subunit protein bL21m", "type": "recommended", "evidence": [ { "id": "Q9VVX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVX4/entry#names_and_taxonomy" } ] }, { "name": "CG9730-PB", "type": "synonym", "evidence": [ { "id": "NP_001262039", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262039" } ] }, { "name": "mRpL21-PB", "type": "synonym", "evidence": [ { "id": "NP_001262039", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262039" } ] }, { "name": "mitochondrial ribosomal protein L21, isoform B", "type": "synonym", "evidence": [ { "id": "NP_001262039", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262039" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VVX4", "url": "https://www.uniprot.org/uniprotkb/Q9VVX4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "mRpL21", "url": "https://www.uniprot.org/uniprotkb/Q9VVX4", "locus": { "chromosome": "3L", "start_pos": 19253290, "end_pos": 19255061, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0036853", "url": "https://www.ensemblgenomes.org/id/FBgn0036853" } ] } } ], "crossref": [ { "id": "FB:FBgn0036853", "url": "https://alliancegenome.org/gene/FB:FBgn0036853", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0036853", "url": "https://bgee.org/?page=gene&gene_id=FBgn0036853", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0036853", "url": "https://flybase.org/reports/FBgn0036853", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "40091", "url": "https://www.ncbi.nlm.nih.gov/gene/40091", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG9730", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG9730", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QWKVTDE", "url": "https://omabrowser.org/oma/group/QWKVTDE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VVX4", "url": "https://www.orthodb.org/?gene=Q9VVX4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21349", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21349", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21349:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21349:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00829", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00829", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-5389840", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-5389840", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-5419276", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-5419276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-9937383", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9937383", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001262039", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262039", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VVX4", "url": "https://www.uniprot.org/uniprotkb/Q9VVX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VVX4-1", "url": "https://www.uniprot.org/uniprotkb/Q9VVX4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSFLAQTMRQMLRHVPNRSLLTAGAMRPLSISPVIGQQNKPATESVDLSAIAKDQQKECLSICERINRQVQKSEQGRLFAVVHLCGKQFKVTPGDIILVEGYWPPTIGDEISLDKVLLAGARDFTLVGRPILEPGLILVKATVVEKTLSHTKTHFRKKRRKQYMRINFQRSPHTMVRINSIELARPVDGNGEGESSSRRLF", "length": 201, "header": "tr|Q9VVX4-1|Q9VVX4_DROME Isoform 1 of Large ribosomal subunit protein bL21m OS=Drosophila melanogaster OX=7227 GN=mRpL21 PE=1 SV=2 CANONICAL=Q9VVX4-1" }, "isoforms": [ { "isoform_ac": "Q9VVX4-1", "url": "https://www.uniprot.org/uniprotkb/Q9VVX4/entry#Q9VVX4-1", "sequence": { "sequence": "MSFLAQTMRQMLRHVPNRSLLTAGAMRPLSISPVIGQQNKPATESVDLSAIAKDQQKECLSICERINRQVQKSEQGRLFAVVHLCGKQFKVTPGDIILVEGYWPPTIGDEISLDKVLLAGARDFTLVGRPILEPGLILVKATVVEKTLSHTKTHFRKKRRKQYMRINFQRSPHTMVRINSIELARPVDGNGEGESSSRRLF", "length": 201, "header": "tr|Q9VVX4-1|Q9VVX4_DROME Isoform 1 of Large ribosomal subunit protein bL21m OS=Drosophila melanogaster OX=7227 GN=mRpL21 PE=1 SV=2 CANONICAL=Q9VVX4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 92, "start_aa": "Thr", "end_pos": 92, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr92", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VVX4", "url": "https://www.uniprot.org/uniprotkb/Q9VVX4" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VVX4", "url": "https://www.uniprot.org/uniprotkb/Q9VVX4" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVX4", "url": "https://www.uniprot.org/uniprotkb/Q9VVX4" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVX4", "url": "https://www.uniprot.org/uniprotkb/Q9VVX4" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VVX4", "url": "https://www.uniprot.org/uniprotkb/Q9VVX4" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VVX4", "url": "https://www.uniprot.org/uniprotkb/Q9VVX4" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VVX4", "url": "https://www.uniprot.org/uniprotkb/Q9VVX4" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVX4", "url": "https://www.uniprot.org/uniprotkb/Q9VVX4" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VVX4", "url": "https://www.uniprot.org/uniprotkb/Q9VVX4" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VVX4", "url": "https://www.uniprot.org/uniprotkb/Q9VVX4" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VVX4", "url": "https://www.uniprot.org/uniprotkb/Q9VVX4" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], 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"authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VW02", "url": "https://www.uniprot.org/uniprotkb/Q9VW02" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VW02", "url": 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"tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VW10-1", "uniprot_ac": "Q9VW10", "uniprot_id": "Q9VW10_DROME", "mass": { "chemical_mass": 76358.0, "monoisotopic_mass": 76358.0 }, "refseq": { "ac": "NP_649127", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649127" }, "gene_names": [ { "name": "Dmel\\CG9300", "type": "recommended", "evidence": [ { "id": "Q9VW10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VW10" } ] }, { "name": "CG9300", "type": "synonym", "evidence": [ { "id": "NP_649127", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649127" }, { "id": "Q9VW10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VW10" } ] }, { "name": "Dmel\\CG9300", "type": "synonym", "evidence": [ { "id": "NP_649127", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649127" } ] }, { "name": "Dmel_CG9300", "type": "synonym", "evidence": [ { "id": "Q9VW10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VW10" } ] }, { "name": "NOL11", "type": "synonym", "evidence": [ { "id": "NP_649127", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649127" }, { "id": "Q9VW10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VW10" } ] } ], "protein_names": [ { "name": "CG9300-PA", "type": "synonym", "evidence": [ { "id": "NP_649127", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649127" } ] }, { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "Q9VW10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VW10/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_649127", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649127" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VW10", "url": "https://www.uniprot.org/uniprotkb/Q9VW10" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG9300", "url": "https://www.uniprot.org/uniprotkb/Q9VW10", "locus": { "chromosome": "3L", "start_pos": 19554767, "end_pos": 19552420, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0036886", "url": "https://www.ensemblgenomes.org/id/FBgn0036886" } ] } } ], "crossref": [ { "id": "FB:FBgn0036886", "url": "https://alliancegenome.org/gene/FB:FBgn0036886", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0036886", "url": "https://bgee.org/?page=gene&gene_id=FBgn0036886", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0036886", "url": "https://flybase.org/reports/FBgn0036886", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "40128", "url": "https://www.ncbi.nlm.nih.gov/gene/40128", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012584", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012584", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048897", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048897", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG9300", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG9300", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QGTTGQC", "url": "https://omabrowser.org/oma/group/QGTTGQC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VW10", "url": "https://www.orthodb.org/?gene=Q9VW10", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15633", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15633", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15633:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15633:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20998", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20998", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6791226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_649127", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649127", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VW10", "url": "https://www.uniprot.org/uniprotkb/Q9VW10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VW10-1", "url": "https://www.uniprot.org/uniprotkb/Q9VW10-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSKFLSYYNLFPIPDPKEFLGLAADRENGNVVTTLARNVVVVLNISTQKQLLSWSLPEKLSSKVIYDPSSQKYVGVFGNHALRLWDVDTSDVSKCKKLKFQKSIAHVVATEQEALILYSDGECQTLSQALASRKDQKEDTAEQLALAASKVISKPTVHALAQGQQVLTYFEETKATGEMQLIRLSLDTADRRKYLIKREEVRLTGYAVVEGDADPQLLTIWSDKRIFMLNLAEATSERSPGQFVSMLAELNVESKLSVHGVSRNFAAIYGANYGQEGASLLVYNTQFKVVNAKQYFKVYLDFSRLWAGNEHILLAMGHNIAAVRYRMNREVLVDMLGSQFSDTHLSPIELDHINEEEYLESLIKFDGSTKPLNYRAVKSQLNKQMPNLDYQKADGRELAYDPPEVVDQEIDEIIKQHVHGEATICENGLEDVSVTLMTNFFDKGPNNTAVQALVRQLERSGAGEEEIIERILTLFIKTDNTEHVLMCLRRYSNISERMLAWSLRYALDKCKPRHAINGDSNAVPTAKSYSNKELLNAVLACRFDATGIEEHLRYRLELSHVQHLMSHLFDLVNDPNVQLEERPSLNCSPIQTEVQAIQWFGCILTSHFTLLIISKDEALLETLSEWATFLSFYEESLFDLANLLPLLTNIVEKRQVKPMYSTNWYGIEEVVLY", "length": 673, "header": "tr|Q9VW10-1|Q9VW10_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG9300 PE=1 SV=1 CANONICAL=Q9VW10-1" }, "isoforms": [ { "isoform_ac": "Q9VW10-1", "url": "https://www.uniprot.org/uniprotkb/Q9VW10/entry#Q9VW10-1", "sequence": { "sequence": "MSKFLSYYNLFPIPDPKEFLGLAADRENGNVVTTLARNVVVVLNISTQKQLLSWSLPEKLSSKVIYDPSSQKYVGVFGNHALRLWDVDTSDVSKCKKLKFQKSIAHVVATEQEALILYSDGECQTLSQALASRKDQKEDTAEQLALAASKVISKPTVHALAQGQQVLTYFEETKATGEMQLIRLSLDTADRRKYLIKREEVRLTGYAVVEGDADPQLLTIWSDKRIFMLNLAEATSERSPGQFVSMLAELNVESKLSVHGVSRNFAAIYGANYGQEGASLLVYNTQFKVVNAKQYFKVYLDFSRLWAGNEHILLAMGHNIAAVRYRMNREVLVDMLGSQFSDTHLSPIELDHINEEEYLESLIKFDGSTKPLNYRAVKSQLNKQMPNLDYQKADGRELAYDPPEVVDQEIDEIIKQHVHGEATICENGLEDVSVTLMTNFFDKGPNNTAVQALVRQLERSGAGEEEIIERILTLFIKTDNTEHVLMCLRRYSNISERMLAWSLRYALDKCKPRHAINGDSNAVPTAKSYSNKELLNAVLACRFDATGIEEHLRYRLELSHVQHLMSHLFDLVNDPNVQLEERPSLNCSPIQTEVQAIQWFGCILTSHFTLLIISKDEALLETLSEWATFLSFYEESLFDLANLLPLLTNIVEKRQVKPMYSTNWYGIEEVVLY", "length": 673, "header": "tr|Q9VW10-1|Q9VW10_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG9300 PE=1 SV=1 CANONICAL=Q9VW10-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VW10", "url": "https://www.uniprot.org/uniprotkb/Q9VW10" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VW10", "url": "https://www.uniprot.org/uniprotkb/Q9VW10" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VW10", "url": "https://www.uniprot.org/uniprotkb/Q9VW10" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VW10", "url": "https://www.uniprot.org/uniprotkb/Q9VW10" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VW10", "url": "https://www.uniprot.org/uniprotkb/Q9VW10" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VW10", "url": "https://www.uniprot.org/uniprotkb/Q9VW10" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VW10", "url": "https://www.uniprot.org/uniprotkb/Q9VW10" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VW10", "url": "https://www.uniprot.org/uniprotkb/Q9VW10" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VW10", "url": "https://www.uniprot.org/uniprotkb/Q9VW10" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VW10", "url": "https://www.uniprot.org/uniprotkb/Q9VW10" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VW10", "url": "https://www.uniprot.org/uniprotkb/Q9VW10" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG9300", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG9300", "resource": "KEGG Pathway" }, { "id": "R-DME-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K1A9-1", "protein_name": "Nucleolar protein 11", "gene_name": "Nol11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALEEEFTLSTGVLGAGPEGFLGVEPSDKADQFLVTDRGRTVVLYKVSDQKPLGSWSVKQGQTITCPAVCNFQTGEYIMVHDHKVLRIWNNEDVNLDKVFKATLSAEVHRIHSVQRTEPLVLFRRGAARGLEALLAEPQQNIEAVIPDEEVIEWSEVFMLFKQPVLIFITENHGSYVAYVQLCKSHSLSKYILLLGKEEKSAKPNFTARVDGKFISLVSLGSDGCVYETLVPIYSSDTENNQRLVRALMLKTVVSGSARNGSALTILDQDHIAVLGPPLPASKECLSIWNIKFQTLQTSKELPQGTSGQLWYHGEILFMRHGKSLTVIPYKCEASSLASALGKLKHTQESGSHSVPHFVNWETCSEYELGSYSAKQTRTLRKKTETNLHPEVPGVKELLSIIKKDSEKHIEVELRKFLAKSTPDFHTIIGDIVSGLLGRCKVEPSFYPRNCLMQLIQTHVLSYSLCPDLMEIALEHTDVQMLQLCLQQFPDIPESTTCACLKLFLSIGDDCLRDSNVSMESVFDYGDTTQDEKKEMEEQTEIVQNGFGPEDGGCSKDSQQLNKKPGDTAQEPISFPVTLCPVAPKRAALLRNAVLHSAYSEPFLLPHLKDIPAKHITLFLQYLYFLYLKCTGSATMTLPGVSPPTVSQIMDWICLLLDANFTVVLMIPEAKRLLLNLYNFVKSQISIYSELNKIEVSFRELQRLNQEKSSRGLYSIEVLELF", "length": 723 }, "evidence": [ { "id": "HGNC:24557", "url": "https://alliancegenome.org/gene/HGNC:24557#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-419", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-419#orthology", "database": "AGR" }, { "id": "MGI:1916229", "url": "https://alliancegenome.org/gene/MGI:1916229#orthology", "database": "AGR" }, { "id": "RGD:1584081", "url": "https://alliancegenome.org/gene/RGD:1584081#orthology", "database": "AGR" }, { "id": "FB:FBgn0036886", "url": "https://alliancegenome.org/gene/FB:FBgn0036886#orthology", "database": "AGR" }, { "id": "Q9VW10", "url": "https://omabrowser.org/oma/group/Q9VW10/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V1AN63-1", "protein_name": "Nucleolar protein 11", "gene_name": "NOL11", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAALCEAFTLCGLGPAGGVGLGSGLLALEPGADPDHVLLTDRGRTTTLFKVSDQKPLGCWSVKHGQIITCPVVCNFETHEYIAVHDNKVLRIWKDEDVNLDKVFKATLSAEVYRIHSLPHAEPLVLFKGGGVRTLDVLLEAPQQEIENVISDEVIKWSEAFLESRQPVLIFVTEKDGDFFVYVQKPKMRSLHKYKLEQQELCNPLSFTAYIKKQIITLLCLYSSDSVYKVLIPLQQSSEEEEQTLSKSLLLNLSISGSVLKGTSFVVLDKDHVAVLGSLAASGEESKECLTIWNTKFQTLQASKELPLGTSGQLWCYGEKFFFTHGKVLTVVIYKCETSSLAAAVGKLKDSQTSDLSSFVNWNTLGDEELLVSLQSQQSVALKSESKMTLRSKKSTVANIQPDTSTVGQFLLSIKDASTAAVEDQLRQLLSKAQMPDFQAAIGCIISALINRCKTDPKFYPRNFLVQMIQKGELSYSLCPDLMAVALEKKDVHLLQICLQRFPDIPEEITYACLKVFLSISDDYLERTDVNLESVISYIDIEPNNKEVKTEVVENGFSTELEEDGCDVTGMKETHMMDSVEFCPVGPQKAALLNAVLHSAYSETFLLPHLKDLPAQQAVLFLRYLHYLYVKCSEKINTTLPGILSPTISQIMDWMCLLLDAHFTVMVMLPEAKGLLSSMHRFVRAQVRLYSELNKIEGSLQELQRIKCQKHSQAYSIEVLELI", "length": 723 }, "evidence": [ { "id": "Q9VW10", "url": "https://omabrowser.org/oma/group/Q9VW10/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q3MHH2-1", "protein_name": "Nucleolar protein 11", "gene_name": "NOL11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MADLEEGFALTAVPLGSGPDGPLGVEQSGKTDQFLVTDSGRTVILYKVSDQKPLGSWSVKQGQIITCPAVCNFQTGEYIVVHDNKVLRIWNNEDVNLDKVFKATLSAEVYRIHSIQGTEPLVLFKEGAVRGLEALLAEPQQKIETVISDEEVIKWTKFFMVFRHPVLIFITEKHGNYFVYVQKFNSRILSKYTLLLGQEEKCVIQSFSTSVGRKFISLMSLSSDGCVYETLIPIHPSEPEKNQRLVQSQLLKSVVSGSARNGVALAILDQDHIAVLGAPLPASKECLSVWNTKFQTLQTSKELPQGTSGQLWYYGENLFMLHGKFLTVVPFKCEVSSLAGALGKLKHSQDPGIHATPHFVNWETSQGCGLGSQNSEQSKRILRRRKVEVSVQPEVPASTQLLATIQKDSEKHIEVELRKFLATKRTPDFHTIIGDVIIGLLGRCKAEPSFYPCNCLMQLVQTHVLSYSLCPGLMEFALEKTDVQILQLCLQQFPDIPESVTCACLKVFLSIGDDTLQDTDINMESVSDYMDPVQDGEMEEQTAFLQNGFSPEEDNCDSCAQKLKEKPQAAADESTSCPVTPKRAALLNAVLHSAYSETFLLPHLKDIPAQHSTLFLQYLYFLYLKCSENATMTLPGTHPPTLSQIMDWICLLLDANFTVVVMIPEAKRLLLSLYKFVKSQISICSELNKIEVSFRELQKLNQEKNNRELYSIEVLELF", "length": 718 }, "evidence": [ { "id": "Q9VW10", "url": "https://omabrowser.org/oma/group/Q9VW10/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q4V9P9-1", "protein_name": "Nucleolar protein 11-like", "gene_name": "nol11", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MATLYEEYTLCGVGPDKNSSSSGILGIELGKDVDHIIVTNSSRAVTVYKVSDQKPTGSWTVKQGQLITCPAVYNTKSQEYVVVTDNKVIRVWKEDDVNMEKAFKATVSSDVLRVIAASDSEPVVLFSCGAVMFLDSLLASPQQTIEGVLTEEEFIRWSTVVGAEHQLVLLFCTEKRGEHYLYAQRFNPNTVVKHRFETEPGPFAPISFSATCRGSNIHLQYLYMSGRIYESVLPLRSSVSEAEGVQALPRSLCLSLPLGEQELTSGAAIVLDEAHVAIVGFPHPSAGAGKDYLCIWNKHFQTLQACKELAGTIYSQIWCYSGKLYIPHGKILSVISFECQKSSLAAAMGKLKQTNQSESKSHTPLSSWTALPHNDSINAAKVKSRMSTRNASNVKSPLTVDQLIDHIKTAVVEDVQSAVGEFIHQTPQTDLQLAAGKVTMVLVSRSQTDDSFYPQRAFLQLLDTRYLCYSVCPELLSLAMAKRDFQLCQIAFQLFPDIPEAVTCAYLKTILSTPDSEMETLTLDTESLIIMKEMSPAQSQMEEGEQQNENGVSSSKQQRDFLSMDMKCPVGLHKGVLLNDVLQTAYSDKPLLQHLKDLTVLQVMVFLQYLHFLYLKYSQDVHKQIRALRIPSISQVIDWASLILDAHFTVLAVAPEAKSLVSDLHKFTRSQVKLYAELGKIEGSLQSLKKPKSTEHTGVYSIEVIELF", "length": 708 }, "evidence": [ { "id": "HGNC:24557", "url": "https://alliancegenome.org/gene/HGNC:24557#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-419", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-419#orthology", "database": "AGR" }, { "id": "MGI:1916229", "url": "https://alliancegenome.org/gene/MGI:1916229#orthology", "database": "AGR" }, { "id": "RGD:1584081", "url": "https://alliancegenome.org/gene/RGD:1584081#orthology", "database": "AGR" }, { "id": "FB:FBgn0036886", "url": "https://alliancegenome.org/gene/FB:FBgn0036886#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8BJW5-1", "protein_name": "Nucleolar protein 11", "gene_name": "Nol11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATLEEEFTLSTGVLGAGPEGFLGVEQTDKADQFLVTDSGRTVVLYKVSDQKPLGSWSVKQGQSITCPAVCNFQTGEYIMVHDHKVLRIWNNDDVNVDKVFKATLSAEVHRIHSVQRTEPLVLFRGGAARGLEALLVEPQQNIESVIPDEEVIVWSEVFMLFKQPVLIFITENHGHYYAYVRLCKSHSLSKYTLLLEKEEKSVKPNFTARVDGKFISLVSLSSDGCIYETLIPIYSSDTEQNQRLVRALMLKSVVSGGVRNGVALTILDQDHIAVLGPPLSASKECLSIWNIKFQTLQTSKELPQGTSGQLWYHGEVLFMLHGKSLTVIPYKCEESSLAGALGKLKHTQESGTHSVPHFVNWETCSGYELGSSGAEQSRTLRRKKVETNLQPEVPGFKQLLSIIKKDSEKHIEVELRKFLAKSTPAFHTIIGDLVAGLVGRCKAEPSFYPRNCLTQLIQTHVLSYSLCPDLMEIALEHTDVQMLQLCLQQFPDIPESTTCACLKLFLSVGDDCLRDSNINMESVFDYSDSTQDEKKEMEEQIEIVQNGFGPEDGNCSEDSQQLNDKPADTAHEPGSFPVTSCPVAPKRAALLNAVLHSAYSEPFLLPHLKDIPAKHVTLFLQYLYFLYLKCTGSATMTLPGVNPPTVSQIMDWICLLLDANFTVLLMIPEAKRLLLILYNFVKSQISIYSELNKIAVSFRELQRLNREKSSRGLYSIEVLELF", "length": 723 }, "evidence": [ { "id": "HGNC:24557", "url": "https://alliancegenome.org/gene/HGNC:24557#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-419", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-419#orthology", "database": "AGR" }, { "id": "MGI:1916229", "url": "https://alliancegenome.org/gene/MGI:1916229#orthology", "database": "AGR" }, { "id": "RGD:1584081", "url": "https://alliancegenome.org/gene/RGD:1584081#orthology", "database": "AGR" }, { "id": "FB:FBgn0036886", "url": "https://alliancegenome.org/gene/FB:FBgn0036886#orthology", "database": "AGR" }, { "id": "Q9VW10", "url": "https://omabrowser.org/oma/group/Q9VW10/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H8H0-1", "protein_name": "Nucleolar protein 11", "gene_name": "NOL11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAALEEEFTLSSVVLSAGPEGLLGVEQSDKTDQFLVTDSGRTVILYKVSDQKPLGSWSVKQGQIITCPAVCNFQTGEYVVVHDNKVLRIWNNEDVNLDKVFKATLSAEVYRILSVQGTEPLVLFKEGAVRGLEALLADPQQKIETVISDEEVIKWTKFFVVFRHPVLIFITEKHGNYFAYVQMFNSRILTKYTLLLGQDENSVIKSFTASVDRKFISLMSLSSDGCIYETLIPIRPADPEKNQSLVKSLLLKAVVSGNARNGVALTALDQDHVAVLGSPLAASKECLSVWNIKFQTLQTSKELPQGTSGQLWYYGEHLFMLHGKSLTVIPYKCEVSSLAGALGKLKHSQDPGTHVVSHFVNWETPQGCGLGFQNSEQSRRILRRRKIEVSLQPEVPPSKQLLSTIMKDSEKHIEVEVRKFLALKQTPDFHTVIGDTVTGLLERCKAEPSFYPRNCLMQLIQTHVLSYSLCPDLMEIALKKKDVQLLQLCLQQFPDIPESVTCACLKIFLSIGDDSLQETDVNMESVFDYSINSVHDEKMEEQTEILQNGFNPEEDKCNNCDQELNKKPQDETKESTSCPVVQKRAALLNAILHSAYSETFLLPHLKDIPAQHITLFLKYLYFLYLKCSENATMTLPGIHPPTLNQIMDWICLLLDANFTVVVMMPEAKRLLINLYKLVKSQISVYSELNKIEVSFRELQKLNQEKNNRGLYSIEVLELF", "length": 719 }, "evidence": [ { "id": "HGNC:24557", "url": "https://alliancegenome.org/gene/HGNC:24557#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-419", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-419#orthology", "database": "AGR" }, { "id": "MGI:1916229", "url": "https://alliancegenome.org/gene/MGI:1916229#orthology", "database": "AGR" }, { "id": "RGD:1584081", "url": "https://alliancegenome.org/gene/RGD:1584081#orthology", "database": "AGR" }, { "id": "FB:FBgn0036886", "url": "https://alliancegenome.org/gene/FB:FBgn0036886#orthology", "database": "AGR" }, { "id": "Q9VW10", "url": "https://omabrowser.org/oma/group/Q9VW10/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q9VW10", "url": "https://www.uniprot.org/uniprotkb/Q9VW10" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q9VW10", "url": "https://www.uniprot.org/uniprotkb/Q9VW10" } ], "pmid": "" }, { "name": "maturation of SSU-rRNA", "id": "GO:0030490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030490", "evidence": [ { "database": "UniProtKB", "id": "Q9VW10", "url": "https://www.uniprot.org/uniprotkb/Q9VW10" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 446, "end_pos": 448, "annotation": "n_glycosylation_sequon" }, { "start_pos": 44, "end_pos": 46, "annotation": "n_glycosylation_sequon" }, { "start_pos": 493, "end_pos": 495, "annotation": "n_glycosylation_sequon" }, { "start_pos": 586, "end_pos": 588, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VW10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VW10" }, { "id": "PF20998", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20998" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nucleolar protein 11 C-terminal", "eco_id": "ECO_0000259", "start_pos": 403, "end_pos": 673, "start_aa": "Pro", "end_aa": "Tyr", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q9VW10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VW10" }, { "id": "PF08168", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08168" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nucleolar protein 11 N-terminal", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 326, "start_aa": "Met", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 446, "end_pos": 448 }, { "start_pos": 44, "end_pos": 46 }, { "start_pos": 493, "end_pos": 495 }, { "start_pos": 586, "end_pos": 588 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", 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Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VW73", "url": "https://www.uniprot.org/uniprotkb/Q9VW73" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, 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melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VW76", "url": "https://www.uniprot.org/uniprotkb/Q9VW76" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG14186", "url": "https://www.uniprot.org/uniprotkb/Q9VW76", "locus": { "chromosome": "3L", "start_pos": 20098084, "end_pos": 20103827, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0036935", "url": "https://www.ensemblgenomes.org/id/FBgn0036935" } ] } } ], "crossref": [ { "id": "FB:FBgn0036935", "url": "https://alliancegenome.org/gene/FB:FBgn0036935", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0036935", "url": "https://bgee.org/?page=gene&gene_id=FBgn0036935", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0036935", "url": "https://flybase.org/reports/FBgn0036935", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "40196", "url": "https://www.ncbi.nlm.nih.gov/gene/40196", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029409", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029409", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG14186", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG14186", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SYADTRC", "url": "https://omabrowser.org/oma/group/SYADTRC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VW76", "url": "https://www.orthodb.org/?gene=Q9VW76", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28388", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28388", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28388:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28388:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15383", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15383", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_649174", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649174", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VW76", "url": "https://www.uniprot.org/uniprotkb/Q9VW76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VW76-1", "url": "https://www.uniprot.org/uniprotkb/Q9VW76-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAKVHRQHQRHRRTEARQRRLEREAVATGAAAPTPTTPERAEALDCATALNEGVVSADPGGSGGTPSSAGRISAQSSADSIELVGSPSQTSQQTVVLVNGHAPPGQEEGEEESPLGAGNTRDSPPPPKQSDGSRNSSGDAMSLRETLQQLPATHHHRSRRTHSPADPDASFHRGILGYMDRELKQSSPTPSAPAGTGNGTGNGTSTGASRKQQSLSDPQASPAQRSLRSRSSFDKSPRRKRSKSESRRRRERKLIAAGEMEVRQANETLMRYLKQCSDMHDASLSGELEIDQSLEERRVHRKTKSQRDKRGQLISKLYSAGGISSILKELADDIAPADGEEIYNPFTPVVSPTDDAPAHIDKMFLQTSSGYRPVEHSYYKRSFLGAAVRGSAGISASGGGGGCAGGGGGRLDGISAAELGGAGRLFRSSGSHAHGGDRMGGNGSGRGSYGDTRCLLDADFNRNGITSNIQLACVVQRIWLLISNICHGLLAGLALAHLLFVLSSHPMDWAKVINGMSLAGETVSSTAQPPAASTPSAIDIDSGDRGTESGESSSPSAAASGLALISDYAGFAEIYLNTFYCLAIICLVSVFDRMDICRWSFSNASELISFRWLIITMIYVATIILAICSDSIDEKLYLFNNNANITLTQQEMLSNSVQSVWSSLSVTRSIAAISGWIMIGLTPQEDMLYEHLVDLTKYQLTNN", "length": 704, "header": "tr|Q9VW76-1|Q9VW76_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG14186 PE=3 SV=2 CANONICAL=Q9VW76-1" }, "isoforms": [ { "isoform_ac": "Q9VW76-1", "url": "https://www.uniprot.org/uniprotkb/Q9VW76/entry#Q9VW76-1", "sequence": { "sequence": "MEAKVHRQHQRHRRTEARQRRLEREAVATGAAAPTPTTPERAEALDCATALNEGVVSADPGGSGGTPSSAGRISAQSSADSIELVGSPSQTSQQTVVLVNGHAPPGQEEGEEESPLGAGNTRDSPPPPKQSDGSRNSSGDAMSLRETLQQLPATHHHRSRRTHSPADPDASFHRGILGYMDRELKQSSPTPSAPAGTGNGTGNGTSTGASRKQQSLSDPQASPAQRSLRSRSSFDKSPRRKRSKSESRRRRERKLIAAGEMEVRQANETLMRYLKQCSDMHDASLSGELEIDQSLEERRVHRKTKSQRDKRGQLISKLYSAGGISSILKELADDIAPADGEEIYNPFTPVVSPTDDAPAHIDKMFLQTSSGYRPVEHSYYKRSFLGAAVRGSAGISASGGGGGCAGGGGGRLDGISAAELGGAGRLFRSSGSHAHGGDRMGGNGSGRGSYGDTRCLLDADFNRNGITSNIQLACVVQRIWLLISNICHGLLAGLALAHLLFVLSSHPMDWAKVINGMSLAGETVSSTAQPPAASTPSAIDIDSGDRGTESGESSSPSAAASGLALISDYAGFAEIYLNTFYCLAIICLVSVFDRMDICRWSFSNASELISFRWLIITMIYVATIILAICSDSIDEKLYLFNNNANITLTQQEMLSNSVQSVWSSLSVTRSIAAISGWIMIGLTPQEDMLYEHLVDLTKYQLTNN", "length": 704, "header": "tr|Q9VW76-1|Q9VW76_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG14186 PE=3 SV=2 CANONICAL=Q9VW76-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 190, "start_aa": "Thr", "end_pos": 190, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr190", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 35, "start_aa": "Thr", "end_pos": 35, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr35", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 37, "start_aa": "Thr", "end_pos": 37, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr37", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 535, "start_aa": "Thr", "end_pos": 535, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr535", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 66, "start_aa": "Thr", "end_pos": 66, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr66", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VW76", "url": "https://www.uniprot.org/uniprotkb/Q9VW76" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VW76", "url": "https://www.uniprot.org/uniprotkb/Q9VW76" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VW76", "url": "https://www.uniprot.org/uniprotkb/Q9VW76" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VW76", "url": "https://www.uniprot.org/uniprotkb/Q9VW76" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VW76", "url": "https://www.uniprot.org/uniprotkb/Q9VW76" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VW76", "url": "https://www.uniprot.org/uniprotkb/Q9VW76" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VW76", "url": "https://www.uniprot.org/uniprotkb/Q9VW76" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VW76", "url": "https://www.uniprot.org/uniprotkb/Q9VW76" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VW76", "url": "https://www.uniprot.org/uniprotkb/Q9VW76" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VW76", "url": "https://www.uniprot.org/uniprotkb/Q9VW76" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VW76", "url": "https://www.uniprot.org/uniprotkb/Q9VW76" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG14186", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG14186", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0L348-1", "protein_name": "Transmembrane protein 237", "gene_name": "Tmem237", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRDDSGPPLEEDKARPPRALPPVPSAIQDEIPLSHPKKKKSRTKSTPAPASSEGLAEPVVNRRAEGSEPPAAELKEYPEAPVQRKQKKIRPPPELETSFTEKPSSPSLLRNENGMDVEPREEVVIPKPRRKAKKMQPAEPQYASELGVEDEDVITDEQSTLEHHSRFTAPTGVSQPVGKIFVEKSRRFQAADRSELIKTTENVDVSMDMKPSWTTRDVALSVHRAFRMIGLFSHGFLAGCAVWNIVVICVLAGDQFSNVSNLLQQYKPLAYPFQSLLYLLLALSTVSAFDRIDFAKTSVAIRNFLALEPTALASFLYFTALTLSLSQQMTSDRIYLYEPSVNGSLWPAEVEEPVLMPWVIVNLVVALLVGLAWLFLSYRPGMDLSEELMFFSDVDEYPERGVKASP", "length": 406 }, "evidence": [ { "id": "RGD:1306705", "url": "https://alliancegenome.org/gene/RGD:1306705#orthology", "database": "AGR" }, { "id": "MGI:2138365", "url": "https://alliancegenome.org/gene/MGI:2138365#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070402-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070402-3#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040912-63", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040912-63#orthology", "database": "AGR" }, { "id": "HGNC:14432", "url": "https://alliancegenome.org/gene/HGNC:14432#orthology", "database": "AGR" }, { "id": "FB:FBgn0036935", "url": "https://alliancegenome.org/gene/FB:FBgn0036935#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1Q930-1", "protein_name": "Transmembrane protein 237A", "gene_name": "tmem237a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MCVTSRADKMPSVKPKKKKIKKEINEVEEPEAGPEPAIEMEGLESRRQSESREPLTPEPHDNPPLKKKKKKKTHTFENEGEQQDHPNGDVQESPTDGEEVTKKSKKKRKNKMMENQSHNELGVEEDDIITDVHAPISQRSLFSAPLSHSHPIGKVFVEKNRRFQATDLSHDHLEEYMEVRPMWNTRDVAMRVHSGFRIIGLFSHGFLAGYAVWNIIVVYVLAGEQMTTLPNLLQQYHSLAYPAQSLLYLLLAISTVSAFDRVNLAKASMALRGFLTLDPAALASFLYFAALILSLSQQMTSDRIHLYPTANETLWPPGLEHQILQPWIVVNLVVALLVGLAWVFVATRPDMDYTEEFLMAMEVEEYPRHDDKHELAA", "length": 377 }, "evidence": [ { "id": "RGD:1306705", "url": "https://alliancegenome.org/gene/RGD:1306705#orthology", "database": "AGR" }, { "id": "MGI:2138365", "url": "https://alliancegenome.org/gene/MGI:2138365#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070402-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070402-3#orthology", "database": "AGR" }, { "id": "HGNC:14432", "url": "https://alliancegenome.org/gene/HGNC:14432#orthology", "database": "AGR" }, { "id": "FB:FBgn0036935", "url": "https://alliancegenome.org/gene/FB:FBgn0036935#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q3V0J1-1", "protein_name": "Transmembrane protein 237", "gene_name": "Tmem237", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRDDSGPPLEEDQARPPRALPPVPSAIQVCSSFVENNSRMDQQDDLVGEDDIPLSHPKKKKSRTKSSLATASSEGHAEPVVNRRAEGSEPPAAELKEHPEAPAPRRQKKIRPPPELETSLTERPSSPSLLRNENGIDAEPREEAVIPKPRRKAKKTQPAEPQYASELGVEDEDILTDEQSTLEHHSRFTAPTGVSQPVGKVFVEKSRRFQAADRSELIKTTENIDVSMDVKPSWTTRDVALSVHRAFRMVGLFSHGFLAGCAVWNTVVIYVLAGDQLSNVSNLLQQYKPLAYPFQSLLYLLLALSTVSAFDRTDFAKISVAIRNFLALEPTALASFLYFTALILSLSQQMTSDRIHLYEPSVNGSLWAAEAEEPILVPWIIVNLVVALLVGLSWLFLSYRPGMDLSEELMFFSDVDEHPETGTKASP", "length": 427 }, "evidence": [ { "id": "RGD:1306705", "url": "https://alliancegenome.org/gene/RGD:1306705#orthology", "database": "AGR" }, { "id": "MGI:2138365", "url": "https://alliancegenome.org/gene/MGI:2138365#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070402-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070402-3#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040912-63", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040912-63#orthology", "database": "AGR" }, { "id": "HGNC:14432", "url": "https://alliancegenome.org/gene/HGNC:14432#orthology", "database": "AGR" }, { "id": "FB:FBgn0036935", "url": "https://alliancegenome.org/gene/FB:FBgn0036935#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q66IE4-1", "protein_name": "Transmembrane protein 237B", "gene_name": "tmem237b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDPEAKVSSSRRRDLPPIPQGQRRTPRALPSMPSQDTAEEMPAPKSRKKKAKRDAESVDEPDDGGMEMGGLASRRQSECPEPLTPEPLDNPPQRRKKKKKAQAIDAEGDQTDLVSNGDTLDQNTDEEVTRKPKKRKVKPKVTETQSNNELDVEDDDVITDPQSPIPQHSLFSAPQGPSQPVGKVFVEKSRRFQAADRVEQWKPSGPIEQSIMDIRSMWTTRDVSMRVHSGFRVIGLFSHGFLAGYAVWNIIVVYVLAGDQMSSLSNLLQQFHTLAYPAQSLLYLLLALSTVSAFDRVNLAKAPAAMRSLLRLSPVALASVFYFSALVLSLSQQMTSDRINLYKYSSYNTTLWPPGSESSILYPWITVNLVVSLLVGLAWILMSTSPDIDNTEAFLMSMEMEYPNSEEKGNVTA", "length": 413 }, "evidence": [ { "id": "RGD:1306705", "url": "https://alliancegenome.org/gene/RGD:1306705#orthology", "database": "AGR" }, { "id": "MGI:2138365", "url": "https://alliancegenome.org/gene/MGI:2138365#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040912-63", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040912-63#orthology", "database": "AGR" }, { "id": "HGNC:14432", "url": "https://alliancegenome.org/gene/HGNC:14432#orthology", "database": "AGR" }, { "id": "FB:FBgn0036935", "url": "https://alliancegenome.org/gene/FB:FBgn0036935#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q96Q45-1", "protein_name": "Transmembrane protein 237", "gene_name": "TMEM237", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRTDSGARLEEGHLRPPRALPPVPSQDDIPLSRPKKKKPRTKNTPASASLEGLAQTAGRRPSEGNEPSTKELKEHPEAPVQRRQKKTRLPLELETSSTQKKSSSSSLLRNENGIDAEPAEEAVIQKPRRKTKKTQPAELQYANELGVEDEDIITDEQTTVEQQSVFTAPTGISQPVGKVFVEKSRRFQAADRSELIKTTENIDVSMDVKPSWTTRDVALTVHRAFRMIGLFSHGFLAGCAVWNIVVIYVLAGDQLSNLSNLLQQYKTLAYPFQSLLYLLLALSTISAFDRIDFAKISVAIRNFLALDPTALASFLYFTALILSLSQQMTSDRIHLYTPSSVNGSLWEAGIEEQILQPWIVVNLVVALLVGLSWLFLSYRPGMDLSEELMFSSEVEEYPDKEKEIKASS", "length": 408 }, "evidence": [ { "id": "RGD:1306705", "url": "https://alliancegenome.org/gene/RGD:1306705#orthology", "database": "AGR" }, { "id": "MGI:2138365", "url": "https://alliancegenome.org/gene/MGI:2138365#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070402-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070402-3#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040912-63", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040912-63#orthology", "database": "AGR" }, { "id": "HGNC:14432", "url": "https://alliancegenome.org/gene/HGNC:14432#orthology", "database": "AGR" }, { "id": "FB:FBgn0036935", "url": "https://alliancegenome.org/gene/FB:FBgn0036935#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VW76", "url": "https://www.uniprot.org/uniprotkb/Q9VW76" } ], "pmid": "" }, { "name": "ciliary transition zone", "id": "GO:0035869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035869", "evidence": [ { "database": "UniProtKB", "id": "Q9VW76", "url": "https://www.uniprot.org/uniprotkb/Q9VW76" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "Q9VW76", "url": "https://www.uniprot.org/uniprotkb/Q9VW76" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 136, "end_pos": 138, "annotation": "n_glycosylation_sequon" }, { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 203, "end_pos": 205, "annotation": "n_glycosylation_sequon" }, { "start_pos": 267, "end_pos": 269, "annotation": "n_glycosylation_sequon" }, { "start_pos": 443, "end_pos": 445, "annotation": "n_glycosylation_sequon" }, { "start_pos": 604, "end_pos": 606, "annotation": "n_glycosylation_sequon" }, { "start_pos": 645, "end_pos": 647, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 35, 37, 66, 190, 535 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 136, "end_pos": 138 }, { "start_pos": 199, "end_pos": 201 }, { "start_pos": 203, "end_pos": 205 }, { "start_pos": 267, "end_pos": 269 }, { "start_pos": 443, "end_pos": 445 }, { "start_pos": 604, "end_pos": 606 }, { "start_pos": 645, "end_pos": 647 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 5 }, { "field": "total_sites", "count": 5 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 5 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 5 }, { "field": "exact_o_linked_sites", "count": 5 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 5 }, { "field": "total_sites", "count": 5 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 5 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 5 }, { "field": "exact_o_linked_sites", "count": 5 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VW89-1", "uniprot_ac": "Q9VW89", "uniprot_id": "Q9VW89_DROME", "mass": { "chemical_mass": 36321.0, "monoisotopic_mass": 36321.0 }, "refseq": { "ac": "NP_649186", "name": "obstructor-F", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649186" }, "gene_names": [ { "name": "obst-F", "type": "recommended", "evidence": [ { "id": "Q9VW89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VW89" } ] }, { "name": "CG7306", "type": "synonym", "evidence": [ { "id": "NP_649186", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649186" }, { "id": "Q9VW89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VW89" } ] }, { "name": "Dmel\\CG7306", "type": "synonym", "evidence": [ { "id": "NP_649186", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649186" }, { "id": "Q9VW89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VW89" } ] }, { "name": "Dmel_CG7306", "type": "synonym", "evidence": [ { "id": "Q9VW89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VW89" } ] }, { "name": "obst-F", "type": "synonym", "evidence": [ { "id": "NP_649186", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649186" } ] } ], "protein_names": [ { "name": "CG7306-PA", "type": "synonym", "evidence": [ { "id": "NP_649186", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649186" } ] }, { "name": "Obstructor-F", "type": "synonym", "evidence": [ { "id": "Q9VW89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VW89/entry#names_and_taxonomy" } ] }, { "name": "obst-F-PA", "type": "synonym", "evidence": [ { "id": "NP_649186", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649186" } ] }, { "name": "obstructor-F", "type": "synonym", "evidence": [ { "id": "NP_649186", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649186" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VW89", "url": "https://www.uniprot.org/uniprotkb/Q9VW89" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "obst-F", "url": "https://www.uniprot.org/uniprotkb/Q9VW89", "locus": { "chromosome": "3L", "start_pos": 20200443, "end_pos": 20201638, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0036947", "url": "https://www.ensemblgenomes.org/id/FBgn0036947" } ] } } ], "crossref": [ { "id": "FB:FBgn0036947", "url": "https://alliancegenome.org/gene/FB:FBgn0036947", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0036947", "url": "https://bgee.org/?page=gene&gene_id=FBgn0036947", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0036947", "url": "https://flybase.org/reports/FBgn0036947", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "40209", "url": "https://www.ncbi.nlm.nih.gov/gene/40209", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002557", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002557", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036508", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036508", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051940", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051940", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG7306", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG7306", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RHPECSK", "url": "https://omabrowser.org/oma/group/RHPECSK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VW89", "url": "https://www.orthodb.org/?gene=Q9VW89", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23301", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23301", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23301:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23301:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01607", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01607", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_649186", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_649186", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VW89", "url": "https://www.uniprot.org/uniprotkb/Q9VW89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VW89-1", "url": "https://www.uniprot.org/uniprotkb/Q9VW89-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQCSWAYVLALSICFQLGAGHAVDQSWELPKVRHTVGHLSHICLGRQEGDLVPHPLDCNGYFSCSRVPTLLYCDQGLQFDENRAICDLPENTNCRPVATGTVESANGLADNSELNWWPHKPKPVFVAVDVTSGQPVNPMEKYDPEHIECRHYGAYFLPHPRNCGLYFICAYGHLHRHQCGRGTAWNFEKSECQLSDQAICYGESQISEPHTDVETTMKVPTANSEGAVTVCYIVGSSEYTTLQQFLTSPEITELPPVTPPSPPRAEANALTCPSTKQSYMSHPEDCSKYYICIGGMPVLTSCPKGLFWDQKSGFCEMEKNVKCFQK", "length": 326, "header": "tr|Q9VW89-1|Q9VW89_DROME Isoform 1 of Obstructor-F OS=Drosophila melanogaster OX=7227 GN=obst-F PE=4 SV=1 CANONICAL=Q9VW89-1" }, "isoforms": [ { "isoform_ac": "Q9VW89-1", "url": "https://www.uniprot.org/uniprotkb/Q9VW89/entry#Q9VW89-1", "sequence": { "sequence": "MQCSWAYVLALSICFQLGAGHAVDQSWELPKVRHTVGHLSHICLGRQEGDLVPHPLDCNGYFSCSRVPTLLYCDQGLQFDENRAICDLPENTNCRPVATGTVESANGLADNSELNWWPHKPKPVFVAVDVTSGQPVNPMEKYDPEHIECRHYGAYFLPHPRNCGLYFICAYGHLHRHQCGRGTAWNFEKSECQLSDQAICYGESQISEPHTDVETTMKVPTANSEGAVTVCYIVGSSEYTTLQQFLTSPEITELPPVTPPSPPRAEANALTCPSTKQSYMSHPEDCSKYYICIGGMPVLTSCPKGLFWDQKSGFCEMEKNVKCFQK", "length": 326, "header": "tr|Q9VW89-1|Q9VW89_DROME Isoform 1 of Obstructor-F OS=Drosophila melanogaster OX=7227 GN=obst-F PE=4 SV=1 CANONICAL=Q9VW89-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 258, "start_aa": "Thr", "end_pos": 258, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr258", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VW89", "url": "https://www.uniprot.org/uniprotkb/Q9VW89" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VW89", "url": "https://www.uniprot.org/uniprotkb/Q9VW89" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VW89", "url": "https://www.uniprot.org/uniprotkb/Q9VW89" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VW89", "url": "https://www.uniprot.org/uniprotkb/Q9VW89" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VW89", "url": "https://www.uniprot.org/uniprotkb/Q9VW89" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VW89", "url": "https://www.uniprot.org/uniprotkb/Q9VW89" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VW89", "url": "https://www.uniprot.org/uniprotkb/Q9VW89" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VW89", "url": "https://www.uniprot.org/uniprotkb/Q9VW89" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VW89", "url": "https://www.uniprot.org/uniprotkb/Q9VW89" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VW89", "url": "https://www.uniprot.org/uniprotkb/Q9VW89" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VW89", "url": "https://www.uniprot.org/uniprotkb/Q9VW89" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], 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"MDTKLAFISGLIMIPTISGALTFNATLICSLVVNGTKMNDPRACNAWIQCIDGSPVSGSCATGLFYDRESQKCLSSSSIKCLSSDPCAALPTGFAADPYSCNGYYYCKDGKGTHGVCNTGMNFNSGTQDCIRDFPCSNKMDPDSYCNILPDGVFVKDTDNCNGYQLCWDGQVINGTCPGTFYFKASTAQCDYPQNVECDFVPVPDISKKGVCPETGGFISDNKTCNGYYYCKDLGNGEFSLEHGVCSDGRFFLATDGGACVPRSKVKCGYDRCVGLGNSTIQLANESDDGCRGYSICQDGIVIGQGTCPQDEYFDEITQRCTTQVISYTACQISEATTGSQVPSGTTTTTSSTITSTTIAVPVS", "length": 364, "header": "tr|Q9VW92-1|Q9VW92_DROME Isoform 1 of Chitin-binding type-2 domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG6996 PE=4 SV=2 CANONICAL=Q9VW92-1" }, "isoforms": [ { "isoform_ac": "Q9VW92-1", "url": "https://www.uniprot.org/uniprotkb/Q9VW92/entry#Q9VW92-1", "sequence": { "sequence": "MDTKLAFISGLIMIPTISGALTFNATLICSLVVNGTKMNDPRACNAWIQCIDGSPVSGSCATGLFYDRESQKCLSSSSIKCLSSDPCAALPTGFAADPYSCNGYYYCKDGKGTHGVCNTGMNFNSGTQDCIRDFPCSNKMDPDSYCNILPDGVFVKDTDNCNGYQLCWDGQVINGTCPGTFYFKASTAQCDYPQNVECDFVPVPDISKKGVCPETGGFISDNKTCNGYYYCKDLGNGEFSLEHGVCSDGRFFLATDGGACVPRSKVKCGYDRCVGLGNSTIQLANESDDGCRGYSICQDGIVIGQGTCPQDEYFDEITQRCTTQVISYTACQISEATTGSQVPSGTTTTTSSTITSTTIAVPVS", "length": 364, "header": "tr|Q9VW92-1|Q9VW92_DROME Isoform 1 of Chitin-binding type-2 domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG6996 PE=4 SV=2 CANONICAL=Q9VW92-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VW92", "url": "https://www.uniprot.org/uniprotkb/Q9VW92" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VW92", "url": "https://www.uniprot.org/uniprotkb/Q9VW92" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VW92", "url": "https://www.uniprot.org/uniprotkb/Q9VW92" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VW92", "url": "https://www.uniprot.org/uniprotkb/Q9VW92" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VW92", "url": "https://www.uniprot.org/uniprotkb/Q9VW92" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VW92", "url": "https://www.uniprot.org/uniprotkb/Q9VW92" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VW92", "url": "https://www.uniprot.org/uniprotkb/Q9VW92" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VW92", "url": "https://www.uniprot.org/uniprotkb/Q9VW92" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VW92", "url": "https://www.uniprot.org/uniprotkb/Q9VW92" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"pathway": [ { "id": "dme:Dmel_CG6996", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG6996", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q9VW92", "url": "https://www.uniprot.org/uniprotkb/Q9VW92" } ], "pmid": "" }, { "name": "external encapsulating structure", "id": "GO:0030312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030312", "evidence": [ { "database": "UniProtKB", "id": "Q9VW92", "url": "https://www.uniprot.org/uniprotkb/Q9VW92" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "chitin binding", "id": "GO:0008061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008061", "evidence": [ { "database": "UniProtKB", "id": "Q9VW92", "url": 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"IPR036508", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036508", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051940", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051940", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG7017", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG7017", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CERYYEC", "url": "https://omabrowser.org/oma/group/CERYYEC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VW93", "url": "https://www.orthodb.org/?gene=Q9VW93", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23301", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23301", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23301:SF106", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23301:SF106", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01607", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01607", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001262095", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262095", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VW93", "url": "https://www.uniprot.org/uniprotkb/Q9VW93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VW93-1", "url": "https://www.uniprot.org/uniprotkb/Q9VW93-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNRASGVLSLLFVASALGGVIEDFEYLSVAEMCDLLPQETSFLRPNTCDNWVRCASNYSVLEQGGCAAGLNYNKELGRCILASSSAAVCPYADSIADKATNLCANETEGAFIVDPSSSDCRGYILCKSHKQIKANCPNELIFHPVSRSCVYEKQYRCPISQTKKTSPACRSLPNNTRLADPVHCDQYYECVSEVLHSRACPVASAYDANLGYCVDVAEVSCYESAALPEPENTFCLDSATGSARVGYFADDESCSHYYICGSPVAGKHDTEPKHLSCPLGQYFDFEKLSCRDRLNVRCQLDRCVGTNITYVNVAGDCQSYGRCSGGVTVSLGQCPTGYYFDERNQGCTQTNYHNIACSV", "length": 359, "header": "tr|Q9VW93-1|Q9VW93_DROME Isoform 1 of Chitin-binding type-2 domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG7017 PE=4 SV=2 CANONICAL=Q9VW93-1" }, "isoforms": [ { "isoform_ac": "Q9VW93-1", "url": "https://www.uniprot.org/uniprotkb/Q9VW93/entry#Q9VW93-1", "sequence": { "sequence": "MNRASGVLSLLFVASALGGVIEDFEYLSVAEMCDLLPQETSFLRPNTCDNWVRCASNYSVLEQGGCAAGLNYNKELGRCILASSSAAVCPYADSIADKATNLCANETEGAFIVDPSSSDCRGYILCKSHKQIKANCPNELIFHPVSRSCVYEKQYRCPISQTKKTSPACRSLPNNTRLADPVHCDQYYECVSEVLHSRACPVASAYDANLGYCVDVAEVSCYESAALPEPENTFCLDSATGSARVGYFADDESCSHYYICGSPVAGKHDTEPKHLSCPLGQYFDFEKLSCRDRLNVRCQLDRCVGTNITYVNVAGDCQSYGRCSGGVTVSLGQCPTGYYFDERNQGCTQTNYHNIACSV", "length": 359, "header": "tr|Q9VW93-1|Q9VW93_DROME Isoform 1 of Chitin-binding type-2 domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG7017 PE=4 SV=2 CANONICAL=Q9VW93-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VW93", "url": "https://www.uniprot.org/uniprotkb/Q9VW93" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VW93", "url": "https://www.uniprot.org/uniprotkb/Q9VW93" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VW93", "url": "https://www.uniprot.org/uniprotkb/Q9VW93" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VW93", "url": "https://www.uniprot.org/uniprotkb/Q9VW93" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VW93", "url": "https://www.uniprot.org/uniprotkb/Q9VW93" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VW93", "url": "https://www.uniprot.org/uniprotkb/Q9VW93" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VW93", "url": "https://www.uniprot.org/uniprotkb/Q9VW93" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VW93", "url": "https://www.uniprot.org/uniprotkb/Q9VW93" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VW93", "url": "https://www.uniprot.org/uniprotkb/Q9VW93" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VW93", "url": "https://www.uniprot.org/uniprotkb/Q9VW93" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VW93", "url": "https://www.uniprot.org/uniprotkb/Q9VW93" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG7017", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG7017", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q9VW93", "url": "https://www.uniprot.org/uniprotkb/Q9VW93" } ], "pmid": "" }, { "name": "external encapsulating structure", "id": "GO:0030312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030312", "evidence": [ { "database": "UniProtKB", "id": "Q9VW93", "url": "https://www.uniprot.org/uniprotkb/Q9VW93" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "chitin binding", "id": "GO:0008061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008061", "evidence": [ { "database": "UniProtKB", "id": "Q9VW93", "url": "https://www.uniprot.org/uniprotkb/Q9VW93" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 105, "end_pos": 107, "annotation": "n_glycosylation_sequon" }, { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" }, { "start_pos": 307, "end_pos": 309, "annotation": "n_glycosylation_sequon" }, { "start_pos": 57, "end_pos": 59, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VW93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VW93" }, { "id": "PS50940", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50940" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Chitin-binding type-2", "eco_id": "ECO_0000259", "start_pos": 30, "end_pos": 91, "start_aa": "Ala", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 105, "end_pos": 107 }, { "start_pos": 174, "end_pos": 176 }, { "start_pos": 307, "end_pos": 309 }, { "start_pos": 57, "end_pos": 59 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VWA6-1", "uniprot_ac": "Q9VWA6", "uniprot_id": "Q9VWA6_DROME", "mass": { "chemical_mass": 67932.0, "monoisotopic_mass": 67932.0 }, "refseq": { "ac": "NP_730506", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_730506" }, "gene_names": [ { "name": "Dmel\\CG17122", "type": "recommended", "evidence": [ { "id": "Q9VWA6", 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"RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_730506" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_730506", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_730506" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VWA6", "url": "https://www.uniprot.org/uniprotkb/Q9VWA6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG17122", "url": "https://www.uniprot.org/uniprotkb/Q9VWA6", "locus": { "chromosome": "3L", "start_pos": 20273389, "end_pos": 20275335, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0036962", "url": "https://www.ensemblgenomes.org/id/FBgn0036962" } ] } } ], "crossref": [ { "id": "FB:FBgn0036962", "url": "https://alliancegenome.org/gene/FB:FBgn0036962", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0036962", "url": "https://bgee.org/?page=gene&gene_id=FBgn0036962", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0036962", "url": "https://flybase.org/reports/FBgn0036962", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "40226", "url": "https://www.ncbi.nlm.nih.gov/gene/40226", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR038844", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038844", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG17122", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG17122", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KIKSLCR", "url": "https://omabrowser.org/oma/group/KIKSLCR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VWA6", "url": "https://www.orthodb.org/?gene=Q9VWA6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31954", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31954", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31954:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31954:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "NP_730506", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_730506", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VWA6", "url": "https://www.uniprot.org/uniprotkb/Q9VWA6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VWA6-1", "url": "https://www.uniprot.org/uniprotkb/Q9VWA6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPPKVKKEKKDVNKVTQVDRTFYELTITDLNQKLARLRSHVTTVDESNITLTEKLKEVEADGVDVAAHLERTLAERNNSITELEERLVEITKVRDVENRVAQEKIGDLESKYKAMHDQLTSEIKLLNGKLNSLDEFRIQRDVLLAKFDEQEADLNEREKDHKEALYNMEQRAVVEKDALKKEVEQKLLQVSEDFTRSSEIRNAGYTRRLIRENIALQKEIDLLVMSQIKLQQAYTNQKSKHKEMEEQYSALDQIKNELVRNSVNKIKIIEGLTRNYEKLKAKYVEVLRYKKAYESLLQAEKCENVKQKDAAGKLRTLAKRMEILDLDNRNLEVVHAQHEIEITRLRGVIQEIKCTVRDAIVAEQAAKKFPERLVEANVDDPAMINEVREEAISLCKLKRSDLLSQLMSIVSSHSEELPKTPSIASIVSATSSLYAPGKMGFMPTRPKATPFDAFRSEVIEQEPDRTVPEDLQKQKMQDRLMTSLRGDENTIIDVEFGTTLYVSSSREDDLIEVEEEPLEEPEGSTSSMSVKKASSEGSVAPPETVPLAVSASSKDIKGAPSIGALDTLTATSKMTGVTNEDEGEEEGEEEDFDVQFVY", "length": 598, "header": "tr|Q9VWA6-1|Q9VWA6_DROME Isoform 1 of Cilia- and flagella-associated protein 157 OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG17122 PE=3 SV=1 CANONICAL=Q9VWA6-1" }, "isoforms": [ { "isoform_ac": "Q9VWA6-1", "url": "https://www.uniprot.org/uniprotkb/Q9VWA6/entry#Q9VWA6-1", "sequence": { "sequence": "MPPKVKKEKKDVNKVTQVDRTFYELTITDLNQKLARLRSHVTTVDESNITLTEKLKEVEADGVDVAAHLERTLAERNNSITELEERLVEITKVRDVENRVAQEKIGDLESKYKAMHDQLTSEIKLLNGKLNSLDEFRIQRDVLLAKFDEQEADLNEREKDHKEALYNMEQRAVVEKDALKKEVEQKLLQVSEDFTRSSEIRNAGYTRRLIRENIALQKEIDLLVMSQIKLQQAYTNQKSKHKEMEEQYSALDQIKNELVRNSVNKIKIIEGLTRNYEKLKAKYVEVLRYKKAYESLLQAEKCENVKQKDAAGKLRTLAKRMEILDLDNRNLEVVHAQHEIEITRLRGVIQEIKCTVRDAIVAEQAAKKFPERLVEANVDDPAMINEVREEAISLCKLKRSDLLSQLMSIVSSHSEELPKTPSIASIVSATSSLYAPGKMGFMPTRPKATPFDAFRSEVIEQEPDRTVPEDLQKQKMQDRLMTSLRGDENTIIDVEFGTTLYVSSSREDDLIEVEEEPLEEPEGSTSSMSVKKASSEGSVAPPETVPLAVSASSKDIKGAPSIGALDTLTATSKMTGVTNEDEGEEEGEEEDFDVQFVY", "length": 598, "header": "tr|Q9VWA6-1|Q9VWA6_DROME Isoform 1 of Cilia- and flagella-associated protein 157 OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG17122 PE=3 SV=1 CANONICAL=Q9VWA6-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 16, "start_aa": "Thr", "end_pos": 16, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr16", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "Q9VWA6", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9VWA6" } ], "filter_code": "00000000000000001000.0000000.00000001000000.1000000.0100000000.110100100001111011.10000.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_reported_with_glycan" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VWA6", "url": "https://www.uniprot.org/uniprotkb/Q9VWA6" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VWA6", "url": "https://www.uniprot.org/uniprotkb/Q9VWA6" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWA6", "url": "https://www.uniprot.org/uniprotkb/Q9VWA6" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWA6", "url": "https://www.uniprot.org/uniprotkb/Q9VWA6" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VWA6", "url": "https://www.uniprot.org/uniprotkb/Q9VWA6" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VWA6", "url": "https://www.uniprot.org/uniprotkb/Q9VWA6" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VWA6", "url": "https://www.uniprot.org/uniprotkb/Q9VWA6" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWA6", "url": "https://www.uniprot.org/uniprotkb/Q9VWA6" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWA6", "url": "https://www.uniprot.org/uniprotkb/Q9VWA6" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VWA6", "url": "https://www.uniprot.org/uniprotkb/Q9VWA6" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VWA6", "url": "https://www.uniprot.org/uniprotkb/Q9VWA6" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] }, { "title": "Quantitative and site-specific chemoproteomic profiling of O-GlcNAcylation in Drosophila.", "journal": "Bioorganic & medicinal chemistry", "date": "2025-04-10", "authors": "Lei Cong, Chen Zihan, Hao Yi, Huang Wanping, Chu Tianyu, Xiao Kangming, Zhang Che, Zhou Wen, Li Chenjian, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9VWA6", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9VWA6" } ], "reference": [ { "type": "PubMed", "id": "40245499", "url": "https://glygen.org/publication/PubMed/40245499" } ] } ], "pathway": [ { "id": "dme:Dmel_CG17122", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG17122", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A2BDR7-1", "protein_name": "Cilia- and flagella-associated protein 157", "gene_name": "cfap157", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPPKKNGKKNRDQAIKTGGMEETEQKNAEELTESDKKFYQAQIRDLEERLERYQLKCDELEVQEKDLSSKINNVEKEKKDIVLFLKRTLAKKEDKLNDLAETLSRHQQAQEAERESFESQLSLLRRELQENKEKYTSENMTLAGKLASLEEFSTQRETLIAERRSLEEQLRKQKEDHQAEIYNLEKKAVLDNDRLKKEMLQHVATVAAEFRRVSDEKMPETTLRAMQENLSVTAQLQQLSEKTKELLKENDALRARERQLKRENGITEPLLHEITKKSVANQKVVLQLTEKCKQMQSEVEKCTKLKQDHQELLDIHSAVCTEIEDLRKKHAAVTEDLNQTKAEVERQKKELEEESRMRAQINTVLEEAAVALKEALRDVPEEEDSELKVTVRRSQMMQKLLAVLDGAAALGKGPALTDLMTCRPGALQKTSPHLSHYKTGDLGLVPRKTHSTSTKMGNLSRSAYTSLQKKA", "length": 471 }, "evidence": [ { "id": "RGD:1560002", "url": "https://alliancegenome.org/gene/RGD:1560002#orthology", "database": "AGR" }, { "id": "HGNC:27843", "url": "https://alliancegenome.org/gene/HGNC:27843#orthology", "database": "AGR" }, { "id": "MGI:2447809", "url": "https://alliancegenome.org/gene/MGI:2447809#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060526-118", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-118#orthology", "database": "AGR" }, { "id": "FB:FBgn0036962", "url": "https://alliancegenome.org/gene/FB:FBgn0036962#orthology", "database": "AGR" }, { "id": "Q9VWA6", "url": "https://omabrowser.org/oma/group/Q9VWA6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q0VFX2-1", "protein_name": "Cilia- and flagella-associated protein 157", "gene_name": "Cfap157", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPKKKPNKGGKEMQGKKIGGKKDASGTKTPELAMVEELKEFYHKQIQDLEDRLARYQRKWDELAVREKLFHQEFEQLANNKKEIVAFLKRTLNQKVDEITDLNDQLQSLEVAKDMEKDAFEAQLAQVRHEFQEIKDQLTTENIALGIKLSSLEEFRLQKEELTEKYLALEEQLHRQEGEYKEYVYNLEKKSVLDKDRLRKEIIQRVNLVATEFRKMATNQMWETTRRAILENNSVTLQLNKVSKHGVQLLQENEQLKGTQNKLCQQLEMLENTQEIMARKNIGHKKIILMLTEKCRQQRKGTEETEQLRLLLSQLEQNFQNVQRDNQTLRSEKDQLEAQLKEKQAEANRLQEELTKEQKIRANLKTVLIQATSMLQDIVHMQTEAEDGDFDVVFQLQRKELLQQLLVLLSSGVVLKTQPDMGSHQDKQPQGLSKESQRITQTSKEGAVSLLQQLSTITTYKPGDLGLVPRRPVRIPLKPQDLRPLSYITRMGICQNTNEIYPSGALKRFRKFTLPRPFLHRK", "length": 523 }, "evidence": [ { "id": "RGD:1560002", "url": "https://alliancegenome.org/gene/RGD:1560002#orthology", "database": "AGR" }, { "id": "HGNC:27843", "url": "https://alliancegenome.org/gene/HGNC:27843#orthology", "database": "AGR" }, { "id": "MGI:2447809", "url": "https://alliancegenome.org/gene/MGI:2447809#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060526-118", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-118#orthology", "database": "AGR" }, { "id": "FB:FBgn0036962", "url": "https://alliancegenome.org/gene/FB:FBgn0036962#orthology", "database": "AGR" }, { "id": "Q9VWA6", "url": "https://omabrowser.org/oma/group/Q9VWA6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q4V7B0-1", "protein_name": "Cilia- and flagella-associated protein 157", "gene_name": "Cfap157", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPKKKSNKGGKEIQSKKKIGGRKDTSGSKTPELAMVEELKEFYHKQIQDLEDRLARYQRKWDELAVQEKLFRQEFEQLANNKKEIVAFLKRTLNQRVDEITDLNDQLQSLQVAKEMEKDAFEAQLAQVRHEFQETKDQLTTENIALGIKLSSLEEFRLQKEELTEKYMALEEQLRRQEGEYKDYVYNLEKKSVLDKDRLRKEIIQRVNLVATEFRKVATNQMWETTRRAILENNNVTLQLSKVSKQGVQLLQENEQLKGAQGKLCQQLELLENTQEIMAKKNIGNQKVILMLTEKCRQQRKGTEEAEQLRLQLFQLEQNIETLEKANQTLRSEKDQLDEQLKEQRAEANRLQEELTKEQKIRTNLKTVLTQATSLLRDILQMRPETEDGDFDVVFQLQRKELLQQLLVLLSSAVVSKPQQDMGSHQDKQPAGLSKDSRLIAQTSKQGAASLLQQLSTITTYQPGDLGLVPRRLQVHIPPKPQDLRPLSCVTRMGICKLQNTTEIYPSGALKRFKKFTLPRPFLHTGRPSRCRKPDVAPVPP", "length": 542 }, "evidence": [ { "id": "RGD:1560002", "url": "https://alliancegenome.org/gene/RGD:1560002#orthology", "database": "AGR" }, { "id": "HGNC:27843", "url": "https://alliancegenome.org/gene/HGNC:27843#orthology", "database": "AGR" }, { "id": "MGI:2447809", "url": "https://alliancegenome.org/gene/MGI:2447809#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060526-118", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-118#orthology", "database": "AGR" }, { "id": "FB:FBgn0036962", "url": "https://alliancegenome.org/gene/FB:FBgn0036962#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5JU67-1", "protein_name": "Cilia- and flagella-associated protein 157", "gene_name": "CFAP157", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPKKSVSKAGKELEVKKKGGKKEPVVAVEPPLAKEMKEFYHIQIRDLEDRLARYQRKWDELAVQEKMFRQEFEQLANNKKEIVAFLKRTLNQQVDEITDLNEQLQNLQLAKEMEKDAFEAQLAQVRHEFQETKDQLTTENIILGGKLAALEEFRLQKEEVTDKFTLLEEQVRKQENEFRDYAYNLEKKSVLDKDRLRKEIIQRVNLVANEFHKVTTNRMWETTKRAIKENNGITLQMARVSQQGMKLLQENEQLKGRQNNLCKQLELLENTQKVMARHKRGHQKIILMLTKKCQEQQQDTKEAEELRLLLSQLEQRSLQLQVDNQALKSQRDQLSLQLEQQQVDLQRLQQELANEQKVRASLEAALVQATSFLQNILQMHRDEEDSDVDVTFQPWHKEMLQQLLVMLSSTVATRPQKAACPHQESQSHGPPKESRPSIQLPRTGSLLPQLSDITPYQPGDLGLVPRQVHIPPNPQDLRLLSYITRVGTFRAHSSPEMRAPGSLKRLEKFSLPEVPLRPK", "length": 520 }, "evidence": [ { "id": "RGD:1560002", "url": "https://alliancegenome.org/gene/RGD:1560002#orthology", "database": "AGR" }, { "id": "HGNC:27843", "url": "https://alliancegenome.org/gene/HGNC:27843#orthology", "database": "AGR" }, { "id": "MGI:2447809", "url": "https://alliancegenome.org/gene/MGI:2447809#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060526-118", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-118#orthology", "database": "AGR" }, { "id": "FB:FBgn0036962", "url": "https://alliancegenome.org/gene/FB:FBgn0036962#orthology", "database": "AGR" }, { "id": "Q9VWA6", "url": "https://omabrowser.org/oma/group/Q9VWA6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "Q9VWA6", "url": 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[], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VWC4", "url": "https://www.uniprot.org/uniprotkb/Q9VWC4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "SkpC", "url": "https://www.uniprot.org/uniprotkb/Q9VWC4", "locus": { "chromosome": "X", "start_pos": 19816700, "end_pos": 19816072, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0026175", "url": "https://www.ensemblgenomes.org/id/FBgn0026175" } ] } } ], "crossref": [ { "id": "FB:FBgn0026175", "url": "https://alliancegenome.org/gene/FB:FBgn0026175", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0026175", "url": "https://bgee.org/?page=gene&gene_id=FBgn0026175", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18322", "url": 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"IPR016897", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016897", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036296", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036296", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG11941", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG11941", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DEECAND", "url": "https://omabrowser.org/oma/group/DEECAND/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VWC4", "url": "https://www.orthodb.org/?gene=Q9VWC4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11165", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11165", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01466", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01466", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03931", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03931", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_608358", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608358", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VWC4", "url": "https://www.uniprot.org/uniprotkb/Q9VWC4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VWC4-1", "url": "https://www.uniprot.org/uniprotkb/Q9VWC4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDAPTIKLESSDGMIFSTEVRAAKLSETIKTMLEVSAVENDENAIVPLPKVNAFILSKILTWIYHHKDDDAHGAEGVELSPQSPHDISAWDANFINVDQPTLFEIILAANYLEIKGLVDLCCKTVANMIRGKTPEEIRHTFNIPDEIPSRTAQLGEDL", "length": 158, "header": "tr|Q9VWC4-1|Q9VWC4_DROME Isoform 1 of SKP1-related C OS=Drosophila melanogaster OX=7227 GN=SkpC PE=3 SV=2 CANONICAL=Q9VWC4-1" }, "isoforms": [ { "isoform_ac": "Q9VWC4-1", "url": "https://www.uniprot.org/uniprotkb/Q9VWC4/entry#Q9VWC4-1", "sequence": { "sequence": "MDAPTIKLESSDGMIFSTEVRAAKLSETIKTMLEVSAVENDENAIVPLPKVNAFILSKILTWIYHHKDDDAHGAEGVELSPQSPHDISAWDANFINVDQPTLFEIILAANYLEIKGLVDLCCKTVANMIRGKTPEEIRHTFNIPDEIPSRTAQLGEDL", "length": 158, "header": "tr|Q9VWC4-1|Q9VWC4_DROME Isoform 1 of SKP1-related C OS=Drosophila melanogaster OX=7227 GN=SkpC PE=3 SV=2 CANONICAL=Q9VWC4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VWC4", "url": "https://www.uniprot.org/uniprotkb/Q9VWC4" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VWC4", "url": "https://www.uniprot.org/uniprotkb/Q9VWC4" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWC4", "url": "https://www.uniprot.org/uniprotkb/Q9VWC4" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWC4", "url": "https://www.uniprot.org/uniprotkb/Q9VWC4" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VWC4", "url": "https://www.uniprot.org/uniprotkb/Q9VWC4" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VWC4", "url": "https://www.uniprot.org/uniprotkb/Q9VWC4" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VWC4", "url": "https://www.uniprot.org/uniprotkb/Q9VWC4" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi 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"https://www.uniprot.org/uniprotkb/Q9VWC7/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein, isoform B", "type": "synonym", "evidence": [ { "id": "NP_001259735", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259735" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VWC7", "url": "https://www.uniprot.org/uniprotkb/Q9VWC7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "lincRNA.1023", "url": "https://www.uniprot.org/uniprotkb/Q9VWC7", "locus": { "chromosome": "X", "start_pos": 19759173, "end_pos": 19764874, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0031070", "url": "https://www.ensemblgenomes.org/id/FBgn0031070" } ] } } ], "crossref": [ { "id": "FB:FBgn0031070", "url": "https://alliancegenome.org/gene/FB:FBgn0031070", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0031070", "url": "https://bgee.org/?page=gene&gene_id=FBgn0031070", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0031070", "url": "https://flybase.org/reports/FBgn0031070", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "32993", "url": "https://www.ncbi.nlm.nih.gov/gene/32993", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR042510", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042510", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG12702", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG12702", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HHVQSTE", "url": "https://omabrowser.org/oma/group/HHVQSTE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VWC7", "url": "https://www.orthodb.org/?gene=Q9VWC7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23161", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23161", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23161:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23161:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "NP_001259735", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259735", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VWC7", "url": "https://www.uniprot.org/uniprotkb/Q9VWC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VWC7-1", "url": "https://www.uniprot.org/uniprotkb/Q9VWC7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATLRNHLSAGGGLNHSGPDSPQEPQDAGATLAIGYVREFRMRVACFQVQRSEESLVYVQRSVALLGTKVLPAHFAPTPGNLELARFYVDLYALMGALKNEGAEGDVLWACVGLVQHCSRNLEARQAVVEHFCFVPLLGVLIRHTKRTERVHRLLVLLQDLTYGIKIAWEEPFLAALIEHLVGIVLCTEDVSCTASGGSVRDDDDENTMLALSVLVNLCYKNFAVLFLFLRSVNISAFCRRIQNYGLLAYKMLIILSEDVYSFQQSELCTFLRLSFAGIEDCLKHWNVAQLRHIVDFLLDSQSHPGLHRAMLSHGHFCEDFEKLLDQIDTSNGMDVSQEETSKHQQISLGLVFRLVSYILQMSEEANSCISLDAITPRLYEMVSDWMSSDQCGAAAIELICTLLRLGKRAAVAEMIANDPSHVAKLVASAERPDTDAGQVLATLRLLIALLQETKTNKVVLSKISESYFDKILAAPLALVPQFLSTQSLAQCEVEKACFCLLLLVNVAGIAKKAYLDKCCTLLEQPQLQYCLARGMVSKNEALVAAVLQIAQFEHFPKASVAKHVSAITSSPGGMMTKASAVGSDQVEQLRNLSSIFKANRIFTDKDMVQRVNALLDNIGGIVSRNELASAPTSQVIELYNHRIESLNGTVASLQQRLEQAGEQLTIGTQQAHVQSAELERFQSSNFQLLISQERLQTRCKDLKQQKVELKSNMTILLKQLSENSVQLQANERRLTVKKSEIADLQKDCENLRSKLSAKSEELTKLEAHNKENISRIDKLKKSMAAYEQDMTEKLRTIGERDRELAKTQKALEEQREACKKSEDLISVLETQLQERKAQIESLEMEQKETEDLRKTIMSLMESKKPKRKA", "length": 870, "header": "tr|Q9VWC7-1|Q9VWC7_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=lincRNA.1023 PE=1 SV=1 CANONICAL=Q9VWC7-1" }, "isoforms": [ { "isoform_ac": "Q9VWC7-1", "url": "https://www.uniprot.org/uniprotkb/Q9VWC7/entry#Q9VWC7-1", "sequence": { "sequence": "MATLRNHLSAGGGLNHSGPDSPQEPQDAGATLAIGYVREFRMRVACFQVQRSEESLVYVQRSVALLGTKVLPAHFAPTPGNLELARFYVDLYALMGALKNEGAEGDVLWACVGLVQHCSRNLEARQAVVEHFCFVPLLGVLIRHTKRTERVHRLLVLLQDLTYGIKIAWEEPFLAALIEHLVGIVLCTEDVSCTASGGSVRDDDDENTMLALSVLVNLCYKNFAVLFLFLRSVNISAFCRRIQNYGLLAYKMLIILSEDVYSFQQSELCTFLRLSFAGIEDCLKHWNVAQLRHIVDFLLDSQSHPGLHRAMLSHGHFCEDFEKLLDQIDTSNGMDVSQEETSKHQQISLGLVFRLVSYILQMSEEANSCISLDAITPRLYEMVSDWMSSDQCGAAAIELICTLLRLGKRAAVAEMIANDPSHVAKLVASAERPDTDAGQVLATLRLLIALLQETKTNKVVLSKISESYFDKILAAPLALVPQFLSTQSLAQCEVEKACFCLLLLVNVAGIAKKAYLDKCCTLLEQPQLQYCLARGMVSKNEALVAAVLQIAQFEHFPKASVAKHVSAITSSPGGMMTKASAVGSDQVEQLRNLSSIFKANRIFTDKDMVQRVNALLDNIGGIVSRNELASAPTSQVIELYNHRIESLNGTVASLQQRLEQAGEQLTIGTQQAHVQSAELERFQSSNFQLLISQERLQTRCKDLKQQKVELKSNMTILLKQLSENSVQLQANERRLTVKKSEIADLQKDCENLRSKLSAKSEELTKLEAHNKENISRIDKLKKSMAAYEQDMTEKLRTIGERDRELAKTQKALEEQREACKKSEDLISVLETQLQERKAQIESLEMEQKETEDLRKTIMSLMESKKPKRKA", "length": 870, "header": "tr|Q9VWC7-1|Q9VWC7_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=lincRNA.1023 PE=1 SV=1 CANONICAL=Q9VWC7-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 78, "start_aa": "Thr", "end_pos": 78, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr78", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VWC7", "url": "https://www.uniprot.org/uniprotkb/Q9VWC7" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VWC7", "url": "https://www.uniprot.org/uniprotkb/Q9VWC7" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWC7", "url": "https://www.uniprot.org/uniprotkb/Q9VWC7" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWC7", "url": "https://www.uniprot.org/uniprotkb/Q9VWC7" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VWC7", "url": "https://www.uniprot.org/uniprotkb/Q9VWC7" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VWC7", "url": "https://www.uniprot.org/uniprotkb/Q9VWC7" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VWC7", "url": "https://www.uniprot.org/uniprotkb/Q9VWC7" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWC7", "url": "https://www.uniprot.org/uniprotkb/Q9VWC7" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWC7", "url": "https://www.uniprot.org/uniprotkb/Q9VWC7" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VWC7", "url": "https://www.uniprot.org/uniprotkb/Q9VWC7" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VWC7", "url": "https://www.uniprot.org/uniprotkb/Q9VWC7" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG12702", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG12702", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AT51-1", "protein_name": "Cellular inhibitor of PP2A", "gene_name": "CIP2A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDSTACFKSLLLTISQYKAVKSEANATQLLRHLEVISGQKLTRLFTSNQILPSECLSCLVELLEDPNISVPLILSIVSLLSQLAVDNETRDCLQNTYNLNSVLAGVVCRSSTCHSDSVFLQCLQLLQRLTYNVKIFHSGANIDELITFLIDHIQSSEDELTMPCLGLLANLCRHNLSVQTHIKTLNNVKSFYRTLISFLAHSSLTVVVFALSILSSLTLNEEVGEKLFHARNIHQTFQLIFNILINGDGTLTRKYSVDLLMDLLKNPKIADYLTRYEHFSSCLNQVLGLLNGKDADSSSKVLELLLAFCSVTQLRHVLTQMIFEQSPSGNTILGSRSKCLEPTVVLLRWSSQPLDGSEDCSILALELFKEIFEDIIDTANCSSADRFVTLLLPTILDQLQFTEQNLDESLIRKKCERMVKAIEVLLTLCGDDTLKMHIAKILTTIKCTTLIEQQFTYGKIDLGFGTKVADSELCKLAADVILKTLNLMNKLKHLVPGMEVSFYKILQDPRLITPLAFALTSDNREQVQSGLGILLEAAPLPDFPALVLGESIAANNAYRQQETEHMPRRMPLQSLNHSFPASVKCLTPPVLKDRVPGLNIEELIEKLQSGVVVKDQINDVRISDIMDVYEMKLSTLASKESRLQDLLEAKALALAQADRLIAQYRCQRTQAETEARTLAGMLREVERKNEELGVLLKSQQVESERAQSDIEHLFQHNRKLESVAEEHEVLTKSYMELLQRNETAEKKNKDLQVTCDSLNKQIETVKKLNESLKQQNEKTLAQLIEKEEQRKEVQNQLVDRECKLTKLEQKVKVQEEKIKVLQREREDKEETIGVLRKELNRTEQIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNKHSHMIAMIHSLSGGKISPETVNLSI", "length": 908 }, "evidence": [ { "id": "Q9VWC7", "url": "https://omabrowser.org/oma/group/Q9VWC7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5ZXN3-1", "protein_name": "Cellular inhibitor of PP2A", "gene_name": "Cip2a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSTACLKSLLLSISQYKAVKSEANATQLLRHLEVVSGQKLTRLFTSQQILPSECLSCLVELLEDPNISASLILSIISLLSQLAIDNETRDCLQNIYNLNSVLSGVVCRSSTCHNNSVFLQCIQLLQRLTYNVKFFHSGAHIDDLITFLIGHIQSSEDELTMPCLGLLANLCRHNLSVQTQIKTLSNVKSFYRTLISFLAHSSLTVVVFALSILSSLTLNEEVGEKLFHARNIHQTFQLIFNILINGDGTLTRKYSVDLLMDLLKNPKIADYLTRYEHFSSCLNQVLGLLNVKDPDSSSKVLELLLAFCAVTQLRHVLSQMMFEQPPSGNNILGSRSPKSLEPIVALLRWLSQPLDGADNCAVLALELFKEIFEDVIDTGNCSSTDRFVTLLLPTILDQLQFTEQNLDETLIKNKCERMVKAIEASMMLWAYDTLKTHVVKILTTMKCSMLIEQQFTYGKIDLGFGTKVADSELCKLAADVILKTLILMNKLKQLVPGMEVSFYKILQDPRLITPLAFALTSDNREQVQSGLGILLEAAPLPDFPALVLGESIAANNVYRQQETERLPRKMTLQPLNHCLSASAKCLTPPLSKDNAPALNIEDLIEKLQAGVMVKDQINDIRISDIMDVYEMKLSTLASKESRLQDLLEAKALALAQADRLIAQYRCQRTQAETEARTLAGMLRDVERKNEELSVLLKSQQLESERAQNDIEHLFQHSKKLESVAEEHEILTKSYMELVQRNEDMEKKNADLQTTCESLNKHIETVKKLNESLKQQNEKTIAQLIEKEEQRKEVQSQLVDRECKLSNLHKKSKSQEEKINVLQKEKEDKQETIDILRKELSRTEQIRKELSIKASSLEMQKAQLEGRLEEKESLVKLQQDELNKHSHMIAMIHSLSGGKISPETVNLSI", "length": 909 }, "evidence": [ { "id": "RGD:1310335", "url": "https://alliancegenome.org/gene/RGD:1310335#orthology", "database": "AGR" }, { "id": "MGI:2146335", "url": "https://alliancegenome.org/gene/MGI:2146335#orthology", "database": "AGR" }, { "id": "HGNC:29302", "url": "https://alliancegenome.org/gene/HGNC:29302#orthology", "database": "AGR" }, { "id": "FB:FBgn0031070", "url": "https://alliancegenome.org/gene/FB:FBgn0031070#orthology", "database": "AGR" }, { "id": "Q9VWC7", "url": "https://omabrowser.org/oma/group/Q9VWC7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BWY9-1", "protein_name": "Protein CIP2A", "gene_name": "Cip2a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSTACLKSLLLSISQYKAVKSEANATQLLRHLEVVSGQKLTRLFTSHQILPSECLSCLVELLEDPNISASLILSIISLLSQLAIDNETRDCLQNIYNLNSVLSGVVCRSSACHNDSVFLQCIQLLQRLTYNAKFFHSGAHIDDLITFLIGHVQSSEDELTMPCLGLLANLCRHNLSVQTQIKTLSNVKSFYRTLISFLAHSSLTVVVFALSILSSLTLNEEVGEKLFHARNIHQTFQLIFNILINGDGTLTRKYSVDLLMDLLKNPKIADYLTRYEHFSSCLSQVLGLLNAKDPDSSSKVLELLLAFCAVTQLRHVLSQMMFEQSPSGNILGSRPKSLEPTAALLRWLSQPLDGAENCSVLALELFKEIFEDVIDTGNCSSTDHFVTLLLPTILDQLQFKEQNLDETLVRNKCERMVKAIEVLLTLCGDDSLKMHVVKILTTLKCTTLIEQQFTYGKIDLGFGTKVADSELCKLAADVILKTLTLMNKLKQLVPGMEVSFYKILQDPRLITPLAFALTSDNREQVQSGLGILLEASPLPDFPAFVLGESIAANNVYRQQETEHLPRKMTFQPLNHGFSTSAKCLTPPPSKDNAPALNIEDLIEKLQAGVMVKDQISDIRISDIMDVYEMKLSTLASKESRLQDLLEAKALALAQADRLIAQYRCQRTQAETEARTLAGMLREVERKNEELSVLLKSQQLESERAQNDIEHLFQHSKKLESVAAEHEILTKSYMELVQRNEATEKKNTDLQTTCESLNKHIETMKKLNEALKQQNEKTIAQLIEKEEQRKEVQSQLADRECKLSNLHKIAKSQEEKLNVLQKEKEDKQETIDILRKELSRTEQIRKELSIKASSLEMHKAQLEGRLEEKESLLKLQQEELNKHSHMIAMIHSLSGGKISPETVNLSI", "length": 907 }, "evidence": [ { "id": "RGD:1310335", "url": "https://alliancegenome.org/gene/RGD:1310335#orthology", "database": "AGR" }, { "id": "MGI:2146335", "url": "https://alliancegenome.org/gene/MGI:2146335#orthology", "database": "AGR" }, { "id": "HGNC:29302", "url": "https://alliancegenome.org/gene/HGNC:29302#orthology", "database": "AGR" }, { "id": "FB:FBgn0031070", "url": "https://alliancegenome.org/gene/FB:FBgn0031070#orthology", "database": "AGR" }, { "id": "Q9VWC7", "url": "https://omabrowser.org/oma/group/Q9VWC7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TCG1-1", "protein_name": "Protein CIP2A", "gene_name": "CIP2A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDSTACLKSLLLTVSQYKAVKSEANATQLLRHLEVISGQKLTRLFTSNQILTSECLSCLVELLEDPNISASLILSIIGLLSQLAVDIETRDCLQNTYNLNSVLAGVVCRSSHTDSVFLQCIQLLQKLTYNVKIFYSGANIDELITFLIDHIQSSEDELKMPCLGLLANLCRHNLSVQTHIKTLSNVKSFYRTLITLLAHSSLTVVVFALSILSSLTLNEEVGEKLFHARNIHQTFQLIFNILINGDGTLTRKYSVDLLMDLLKNPKIADYLTRYEHFSSCLHQVLGLLNGKDPDSSSKVLELLLAFCSVTQLRHMLTQMMFEQSPPGSATLGSHTKCLEPTVALLRWLSQPLDGSENCSVLALELFKEIFEDVIDAANCSSADRFVTLLLPTILDQLQFTEQNLDEALTRKKCERIAKAIEVLLTLCGDDTLKMHIAKILTTVKCTTLIEQQFTYGKIDLGFGTKVADSELCKLAADVILKTLDLINKLKPLVPGMEVSFYKILQDPRLITPLAFALTSDNREQVQSGLRILLEAAPLPDFPALVLGESIAANNAYRQQETEHIPRKMPWQSSNHSFPTSIKCLTPHLKDGVPGLNIEELIEKLQSGMVVKDQICDVRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQADRLIAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELNKHSHMIAMIHSLSGGKINPETVNLSI", "length": 905 }, "evidence": [ { "id": "RGD:1310335", "url": "https://alliancegenome.org/gene/RGD:1310335#orthology", "database": "AGR" }, { "id": "MGI:2146335", "url": "https://alliancegenome.org/gene/MGI:2146335#orthology", "database": "AGR" }, { "id": "HGNC:29302", "url": "https://alliancegenome.org/gene/HGNC:29302#orthology", "database": "AGR" }, { "id": "FB:FBgn0031070", "url": "https://alliancegenome.org/gene/FB:FBgn0031070#orthology", "database": "AGR" }, { "id": "Q9VWC7", "url": "https://omabrowser.org/oma/group/Q9VWC7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 15, "end_pos": 17, "annotation": "n_glycosylation_sequon" }, { "start_pos": 234, "end_pos": 236, "annotation": "n_glycosylation_sequon" }, { "start_pos": 592, "end_pos": 594, "annotation": "n_glycosylation_sequon" }, { "start_pos": 648, "end_pos": 650, "annotation": "n_glycosylation_sequon" }, { "start_pos": 713, "end_pos": 715, "annotation": "n_glycosylation_sequon" }, { "start_pos": 773, "end_pos": 775, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 78 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 15, "end_pos": 17 }, { "start_pos": 234, "end_pos": 236 }, { "start_pos": 592, "end_pos": 594 }, { "start_pos": 648, "end_pos": 650 }, { "start_pos": 713, "end_pos": 715 }, { "start_pos": 773, "end_pos": 775 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VWD0-1", "uniprot_ac": "Q9VWD0", "uniprot_id": "Q9VWD0_DROME", "mass": { "chemical_mass": 41863.0, "monoisotopic_mass": 41863.0 }, "refseq": { "ac": "NP_001285464", "name": "parvin, isoform B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285464" }, "gene_names": [ { "name": "parvin", "type": "recommended", "evidence": [ { "id": "Q9VWD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWD0" } ] }, { "name": "CG12533", "type": "synonym", "evidence": [ { "id": "NP_001285464", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285464" }, { "id": "Q9VWD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWD0" } ] }, { "name": "CG32528", "type": "synonym", "evidence": [ { "id": "NP_001285464", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285464" }, { "id": "Q9VWD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWD0" } ] }, { "name": "Dmel\\CG32528", "type": "synonym", "evidence": [ { "id": "NP_001285464", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285464" }, { "id": "Q9VWD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWD0" } ] }, { "name": "Dmel_CG32528", "type": "synonym", "evidence": [ { "id": "Q9VWD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWD0" } ] }, { "name": "parvin", "type": "synonym", "evidence": [ { "id": "NP_001285464", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285464" } ] } ], "protein_names": [ { "name": "CG32528-PB", "type": "synonym", "evidence": [ { "id": "NP_001285464", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285464" } ] }, { "name": "Parvin, isoform A", "type": "synonym", "evidence": [ { "id": "Q9VWD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWD0/entry#names_and_taxonomy" } ] }, { "name": "Parvin, isoform B", "type": "synonym", "evidence": [ { "id": "Q9VWD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWD0/entry#names_and_taxonomy" } ] }, { "name": "parvin, isoform B", "type": "synonym", "evidence": [ { "id": "NP_001285464", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285464" } ] }, { "name": "parvin-PB", "type": "synonym", "evidence": [ { "id": "NP_001285464", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285464" } ] } ], "function": [], "disease": [ { "disease_id": "DOID:162", "recommended_name": { "id": "DOID:162", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:162", "name": "cancer", "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis." }, "synonyms": [ { "id": "DOID:162", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:162", "name": "malignant neoplasm", "description": "" }, { "id": "DOID:162", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:162", "name": "malignant tumor", "description": "" }, { "id": "DOID:162", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:162", "name": "primary cancer", "description": "" } ], "unlinked_id_list": [ "DOID:193", "DOID:7757", "DOID:2151", "DOID:3316", "DOID:370", "DOID:706", "DOID:5604", "DOID:184", "DOID:2599", "DOID:4706", "DOID:2174", "DOID:4015", "DOID:4203", "DOID:170", "DOID:10154", "DOID:3017", "DOID:5166", "DOID:1795", "DOID:3149", "DOID:8527", "DOID:0050938", "DOID:3093", "DOID:0060122", "DOID:201", "DOID:3303", "DOID:3350", "DOID:176", "DOID:2595", "DOID:5093", "DOID:0070003", "DOID:0080355", "DOID:368", "DOID:0080524", "DOID:9460", "DOID:0080639", "DOID:0050619", "DOID:0080638", "DOID:4907", "DOID:1325", "DOID:688", "DOID:771", "DOID:0060073", "DOID:672", "DOID:5772", "DOID:4645", "DOID:0080879", "DOID:4765", "DOID:1357", "DOID:5032", "DOID:0060083", "DOID:0050743", "DOID:4045", "DOID:5672", "DOID:3675", "DOID:5662", "DOID:192", "DOID:4043", "DOID:0060116", "DOID:0080364", "DOID:0060100", "DOID:3095", "DOID:0080525", "DOID:3541", "DOID:4230", "DOID:1294", "DOID:0050615", "DOID:0050687", "DOID:3953", "DOID:5158", "DOID:1039", "DOID:3973", "DOID:8858", "DOID:0060119", "DOID:3111", "DOID:60004", "DOID:5467", "DOID:1036", "DOID:2706", "DOID:3856", "DOID:3112", "DOID:3479", "DOID:2815", "DOID:660", "DOID:120", "DOID:2021", "DOID:4114", "DOID:0081452", "DOID:4455", "DOID:3451", "DOID:175", "DOID:4931", "DOID:3277", "DOID:1659", "DOID:4960", "DOID:3001", "DOID:2621", "DOID:1542", "DOID:3419", "DOID:6536", "DOID:3850" ], "evidence": [ { "id": "162", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:162" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VWD0", "url": "https://www.uniprot.org/uniprotkb/Q9VWD0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "parvin", "url": "https://www.uniprot.org/uniprotkb/Q9VWD0", "locus": { "chromosome": "X", "start_pos": 19748458, "end_pos": 19746041, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0052528", "url": "https://www.ensemblgenomes.org/id/FBgn0052528" } ] } } ], "crossref": [ { "id": "FB:FBgn0052528", "url": "https://alliancegenome.org/gene/FB:FBgn0052528", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0052528", "url": "https://bgee.org/?page=gene&gene_id=FBgn0052528", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd21304", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21304", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21306", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21306", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0052528", "url": "https://flybase.org/reports/FBgn0052528", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "32990", "url": "https://www.ncbi.nlm.nih.gov/gene/32990", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028433", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028433", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036872", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036872", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG32528", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG32528", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VDLLIYW", "url": "https://omabrowser.org/oma/group/VDLLIYW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VWD0", "url": "https://www.orthodb.org/?gene=Q9VWD0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12114", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12114", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12114:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12114:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00307", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00307", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-446343", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-446343", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-446353", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-446353", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-446388", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-446388", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001285464", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285464", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VWD0", "url": "https://www.uniprot.org/uniprotkb/Q9VWD0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VWD0-1", "url": "https://www.uniprot.org/uniprotkb/Q9VWD0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTLNRPKSPHTPTAIKKGEKEDSFWDKFSTLGRKRGTREVKKVQEEGKYAIDSPGSPSQYDIPPEDYALREHEQRAVIDPQSISDPQVIKLQRILVDWINDELAEQRIIVQHLEEDMYDGQVLHKLWEKLTGKKLDVPEVTQSEQGQHEKLNIVLKAVNHTLGFHQKIPKWSVASVHSKNIVAILHLLVALVRHFRAPVRLPENVFVTVVIAEKNAGVLNAQKFQEQITSEYDDLGMRCEKDAFDTLIDCAPDKLAVVKKSLITFVNKHLAKLNFEISDLNTDFRDGVYLCLLMGLLGGFFVPLHEFHLTPQDVDQMVSNVAFAFDLMQDVGLPKPKARPEDIVNMDLKSTLRVLYSLFTMFRDFA", "length": 367, "header": "tr|Q9VWD0-1|Q9VWD0_DROME Isoform 1 of Parvin, isoform B OS=Drosophila melanogaster OX=7227 GN=parvin PE=1 SV=2 CANONICAL=Q9VWD0-1" }, "isoforms": [ { "isoform_ac": "Q9VWD0-1", "url": "https://www.uniprot.org/uniprotkb/Q9VWD0/entry#Q9VWD0-1", "sequence": { "sequence": "MSTLNRPKSPHTPTAIKKGEKEDSFWDKFSTLGRKRGTREVKKVQEEGKYAIDSPGSPSQYDIPPEDYALREHEQRAVIDPQSISDPQVIKLQRILVDWINDELAEQRIIVQHLEEDMYDGQVLHKLWEKLTGKKLDVPEVTQSEQGQHEKLNIVLKAVNHTLGFHQKIPKWSVASVHSKNIVAILHLLVALVRHFRAPVRLPENVFVTVVIAEKNAGVLNAQKFQEQITSEYDDLGMRCEKDAFDTLIDCAPDKLAVVKKSLITFVNKHLAKLNFEISDLNTDFRDGVYLCLLMGLLGGFFVPLHEFHLTPQDVDQMVSNVAFAFDLMQDVGLPKPKARPEDIVNMDLKSTLRVLYSLFTMFRDFA", "length": 367, "header": "tr|Q9VWD0-1|Q9VWD0_DROME Isoform 1 of Parvin, isoform B OS=Drosophila melanogaster OX=7227 GN=parvin PE=1 SV=2 CANONICAL=Q9VWD0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VWD0", "url": "https://www.uniprot.org/uniprotkb/Q9VWD0" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VWD0", "url": "https://www.uniprot.org/uniprotkb/Q9VWD0" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWD0", "url": "https://www.uniprot.org/uniprotkb/Q9VWD0" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWD0", "url": "https://www.uniprot.org/uniprotkb/Q9VWD0" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VWD0", "url": "https://www.uniprot.org/uniprotkb/Q9VWD0" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VWD0", "url": "https://www.uniprot.org/uniprotkb/Q9VWD0" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VWD0", "url": "https://www.uniprot.org/uniprotkb/Q9VWD0" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWD0", "url": "https://www.uniprot.org/uniprotkb/Q9VWD0" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWD0", "url": "https://www.uniprot.org/uniprotkb/Q9VWD0" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VWD0", "url": "https://www.uniprot.org/uniprotkb/Q9VWD0" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VWD0", "url": "https://www.uniprot.org/uniprotkb/Q9VWD0" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG32528", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG32528", "resource": "KEGG Pathway" }, { "id": "R-DME-446343", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-446343", "resource": "Reactome", "description": "Localization of the PINCH-ILK-PARVIN complex to focal adhesions" }, { "id": "R-DME-446353", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-446353", "resource": "Reactome", "description": "Cell-extracellular matrix interactions" }, { "id": "R-DME-446388", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-446388", "resource": "Reactome", "description": "Regulation of cytoskeletal remodeling and cell spreading by IPP complex components" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2KB09-1", "protein_name": "Parvin, beta", "gene_name": "Parvb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSALPRSPTPRAPKMKKDESFLGKLGGTLARKKKTREVTDLQEEGKSAINSPMAPALVDIHPEDTQLEENEERTMIDPTSREDPKFKELVKVLLDWINDVLAEERIIVKQLEEDLYDGQVLQKLLEKLAHCKLNVAEVTQSEIGQKQKLQTVLEAVQDLLRPHGWPLRWNVDSIHGKNLVSILHLLVSLAMHFRAPIHLPEHVTVQVVVVRKREGLLHSSHISEELTTTTEIMMGRFERDAFDTLFDHAPDKLNLVKKSLITFVNKHLNKLNLEVTDLETQFADGVYLVLLLGLLEDYFVPLHNFYLTPDSFDQKVHNVAFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVLYTLFTKYKDVE", "length": 365 }, "evidence": [ { "id": "HGNC:14653", "url": "https://alliancegenome.org/gene/HGNC:14653#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-4411", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-4411#orthology", "database": "AGR" }, { "id": "MGI:2153063", "url": "https://alliancegenome.org/gene/MGI:2153063#orthology", "database": "AGR" }, { "id": "RGD:1311485", "url": "https://alliancegenome.org/gene/RGD:1311485#orthology", "database": "AGR" }, { "id": "FB:FBgn0052528", "url": "https://alliancegenome.org/gene/FB:FBgn0052528#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A287B7K9-1", "protein_name": "Parvin alpha", "gene_name": "PARVA", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATSPQKSPSVPKSPTPKSPPSRKKDDSFLGKLGGTLARRKKAKEVSELQEEGMNAINLPLSPIPFELDPEDTMLEENEVRTMVDPNSRSDPKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQVLQKLFEKLESEKLNVAEVTQSEIAQKQKLQTVLEKINETLKLPPRSIKWNVDSVHAKSLVAILHLLVALSQYFRAPIRLPDHVSIQVVVVQKREGILQSRQIQEEITGNTEALSGRHERDAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYRNVE", "length": 372 }, "evidence": [ { "id": "Q9VWD0", "url": "https://omabrowser.org/oma/group/Q9VWD0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A3Q1LMM6-1", "protein_name": "Parvin alpha", "gene_name": "PARVA", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MFGASSLLPAAAGAGPERSAPCRAEGGAREGEREGKGERELPRMLGIIPLPFGKPQPQSRRARRVRPAPAPRPDRPAAARSAAMATSPQKSPSVPKSPTPKSPPSRKKDDSFLGKLGGTLARRKKAKEVSELQEEGMNAINLPLSPIPFELDPEDTMLEENEVRTMVDPNSRSDPKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQVLQKLFEKLESEKLNVAEVTQSEIAQKQKLQTVLEKINETLKLPPRSIKWNVDTVHAKSLVAILHLLVALSQYFRAPIRLPDHVSIQVVVVQKREGILQSRQIQEEITGNTEALSGRHERDAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEETLQMEVEDLQLDPHWNPPDDPG", "length": 453 }, "evidence": [ { "id": "Q9VWD0", "url": "https://omabrowser.org/oma/group/Q9VWD0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8C2QGY3-1", "protein_name": "Alpha-parvin isoform X1", "gene_name": "Parva", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MATSPQKSPSVPKSPTPKSPPSRKKDDSFLGKLGGTLARRKKAKEVSEFQEEGMNAINLPLSPISFELDPEDTMLEENEVRTMVDPNSRSDPKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQVLQKLFEKLESEKLNVAEVTQSEIAQKQKLQTVLEKINETLKLPPRSIKWNVDSVHAKSLVAILHLLVALSQYFRAPIRLPDHVSIQVVVVQKREGILQSRQIQEEITGNTEALSGRHERDAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYRNVE", "length": 372 }, "evidence": [ { "id": "Q9VWD0", "url": "https://omabrowser.org/oma/group/Q9VWD0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8M9PMM3-1", "protein_name": "Beta-parvin isoform X2", "gene_name": "parvb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MESMSDLQEEGKNAINAPLLHTSPELLPEDTLLEENAERTILDPTSREDLNFKDLQKVLIDWINSELEEDRIIVKDLEEDLYDGQVLQKLFEKLSGYKLNVAEVTQSEIGQKQKLQTVLEAVNGVLRPLDWNTEWSVDSIHSKNLVSIVYLLLALAIYYAAPIRLPEHVSVQVIVVKKKEGILQTAHVTKQLTSTTTEMMIGRSERDAFDTLLDHAPDKLNVVKTSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLENYFVPLYNFYLTPENFEQKVHNVAFAFELMQDGGLQKPKARPEDVVNLNLKSTLRVLYNLFTNYKNSE", "length": 331 }, "evidence": [ { "id": "HGNC:14653", "url": "https://alliancegenome.org/gene/HGNC:14653#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-4411", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-4411#orthology", "database": "AGR" }, { "id": "MGI:2153063", "url": "https://alliancegenome.org/gene/MGI:2153063#orthology", "database": "AGR" }, { "id": "RGD:1311485", "url": "https://alliancegenome.org/gene/RGD:1311485#orthology", "database": "AGR" }, { "id": "FB:FBgn0052528", "url": "https://alliancegenome.org/gene/FB:FBgn0052528#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0ZN45-1", "protein_name": "Parvin alpha", "gene_name": "PARVA", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MASSPQKSPSSPKSPTPKSPPSRKKDDSFLGKLGGTLARRKKAKEVSELQEEGMNAINLPLSPIPFELDPEDTMLEENEVRTMVDPNSRNDPKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQVLQKLFEKLESEKLNVAEVTQSEIAQKQKLQTVLEKINETLKLPPRSIKWNVDSVHAKSLVAILHLLVALSQYFRAPIRLPDHVSIQVVVVQKREGILQSRQIQEEITGNTEAFSGRHERDAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYRNVE", "length": 372 }, "evidence": [ { "id": "Q9VWD0", "url": "https://omabrowser.org/oma/group/Q9VWD0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q9EPC1-1", "protein_name": "Alpha-parvin", "gene_name": "Parva", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATSPQKSPLVPKSPTPKSPPSRKKDDSFLGKLGGTLARRKKAKEVSEFQEEGMNAINLPLSPISFELDPEDTLLEENEVRTMVDPNSRNDPKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQVLQKLFEKLESEKLNVAEVTQSEIAQKQKLQTVLEKINETLKLPPRSIKWNVDSVHAKNLVAILHLLVALSQYFRAPIRLPDHVSIQVVVVQKREGILQSRQIQEEITGNTEALSGRHERDAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYRNVE", "length": 372 }, "evidence": [ { "id": "RGD:71021", "url": "https://alliancegenome.org/gene/RGD:71021#orthology", "database": "AGR" }, { "id": "HGNC:14652", "url": "https://alliancegenome.org/gene/HGNC:14652#orthology", "database": "AGR" }, { "id": "MGI:1931144", "url": "https://alliancegenome.org/gene/MGI:1931144#orthology", "database": "AGR" }, { "id": "FB:FBgn0052528", "url": "https://alliancegenome.org/gene/FB:FBgn0052528#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9ES46-1", "protein_name": "Beta-parvin", "gene_name": "Parvb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSAPPRSPTPRAPKMKKDESFLGKLGGTLARKKKTREVTDLQEEGKSAINSPMAPALVDIHPEDTQLEENEERTMIDPTSREDPKFKELVKVLLDWINDVLAEERIIVKQLEEDLYDGQVLQKLLEKLAHCKLNVAEVTQSEIGQKQKLQTVLEAVQDLLRPHGWPLRWNVDSIHGKNLVAILHLLVSLAMHFRAPIHLPEHVTVQVVVVRKREGLLHSSHISEELTTTTEIMMGRFERDAFDTLFDHAPDKLNLVKKSLITFVNKHLNKLNLEVTDLETQFADGVYLVLLLGLLEDYFVPLHNFYLTPDSFDQKVHNVAFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVLYTLFTKYKDVE", "length": 365 }, "evidence": [ { "id": "HGNC:14653", "url": "https://alliancegenome.org/gene/HGNC:14653#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-4411", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-4411#orthology", "database": "AGR" }, { "id": "MGI:2153063", "url": "https://alliancegenome.org/gene/MGI:2153063#orthology", "database": "AGR" }, { "id": "RGD:1311485", "url": "https://alliancegenome.org/gene/RGD:1311485#orthology", "database": "AGR" }, { "id": "FB:FBgn0052528", "url": "https://alliancegenome.org/gene/FB:FBgn0052528#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9HB97-1", "protein_name": "Alpha-parvin", "gene_name": "Parva", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATSPQKSPSVPKSPTPKSPPSRKKDDSFLGKLGGTLARRKKAKEVSEFQEEGMNAINLPLSPISFELDPEDTMLEENEVRTMVDPNSRNDPKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQVLQKLFEKLESEKLNVAEVTQSEIAQKQKLQTVLEKINEALKLPPRSIKWNVDSVHAKNLVAILHLLVALSQYFRAPIRLPDHVSIQVVVVQKREGILQSRQIQEEITGNTEALSGRHERDAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYRNVE", "length": 372 }, "evidence": [ { "id": "RGD:71021", "url": "https://alliancegenome.org/gene/RGD:71021#orthology", "database": "AGR" }, { "id": "HGNC:14652", "url": "https://alliancegenome.org/gene/HGNC:14652#orthology", "database": "AGR" }, { "id": "MGI:1931144", "url": "https://alliancegenome.org/gene/MGI:1931144#orthology", "database": "AGR" }, { "id": "FB:FBgn0052528", "url": "https://alliancegenome.org/gene/FB:FBgn0052528#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9HBI1-1", "protein_name": "Beta-parvin", "gene_name": "PARVB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSAPRSPTPRPRRMKKDESFLGKLGGTLARKRRAREVSDLQEEGKNAINSPMSPALVDVHPEDTQLEENEERTMIDPTSKEDPKFKELVKVLLDWINDVLVEERIIVKQLEEDLYDGQVLQKLLEKLAGCKLNVAEVTQSEIGQKQKLQTVLEAVHDLLRPRGWALRWSVDSIHGKNLVAILHLLVSLAMHFRAPIRLPEHVTVQVVVVRKREGLLHSSHISEELTTTTEMMMGRFERDAFDTLFDHAPDKLSVVKKSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHHFYLTPESFDQKVHNVSFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTKYKNVE", "length": 364 }, "evidence": [ { "id": "HGNC:14653", "url": "https://alliancegenome.org/gene/HGNC:14653#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-4411", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-4411#orthology", "database": "AGR" }, { "id": "MGI:2153063", "url": "https://alliancegenome.org/gene/MGI:2153063#orthology", "database": "AGR" }, { "id": "RGD:1311485", "url": "https://alliancegenome.org/gene/RGD:1311485#orthology", "database": "AGR" }, { "id": "FB:FBgn0052528", "url": "https://alliancegenome.org/gene/FB:FBgn0052528#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9NVD7-1", "protein_name": "Alpha-parvin", "gene_name": "PARVA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATSPQKSPSVPKSPTPKSPPSRKKDDSFLGKLGGTLARRKKAKEVSELQEEGMNAINLPLSPIPFELDPEDTMLEENEVRTMVDPNSRSDPKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQVLQKLFEKLESEKLNVAEVTQSEIAQKQKLQTVLEKINETLKLPPRSIKWNVDSVHAKSLVAILHLLVALSQYFRAPIRLPDHVSIQVVVVQKREGILQSRQIQEEITGNTEALSGRHERDAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYRNVE", "length": 372 }, "evidence": [ { "id": "RGD:71021", "url": "https://alliancegenome.org/gene/RGD:71021#orthology", "database": "AGR" }, { "id": "HGNC:14652", "url": "https://alliancegenome.org/gene/HGNC:14652#orthology", "database": "AGR" }, { "id": "MGI:1931144", "url": "https://alliancegenome.org/gene/MGI:1931144#orthology", "database": "AGR" }, { "id": "FB:FBgn0052528", "url": "https://alliancegenome.org/gene/FB:FBgn0052528#orthology", "database": "AGR" }, { "id": "Q9VWD0", "url": "https://omabrowser.org/oma/group/Q9VWD0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "Q9VWD0", "url": "https://www.uniprot.org/uniprotkb/Q9VWD0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VWD0", "url": "https://www.uniprot.org/uniprotkb/Q9VWD0" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "Q9VWD0", "url": "https://www.uniprot.org/uniprotkb/Q9VWD0" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "Q9VWD0", "url": "https://www.uniprot.org/uniprotkb/Q9VWD0" } ], "pmid": "" }, { "name": "sarcomere", "id": "GO:0030017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030017", "evidence": [ { "database": "UniProtKB", "id": "Q9VWD0", "url": "https://www.uniprot.org/uniprotkb/Q9VWD0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "Q9VWD0", "url": "https://www.uniprot.org/uniprotkb/Q9VWD0" } ], "pmid": "" }, { "name": "substrate adhesion-dependent cell spreading", "id": "GO:0034446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034446", "evidence": [ { "database": "UniProtKB", "id": "Q9VWD0", "url": "https://www.uniprot.org/uniprotkb/Q9VWD0" } ], "pmid": "" }, { "name": "establishment or maintenance of cell polarity regulating cell shape", "id": "GO:0071963", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071963", "evidence": [ { "database": "UniProtKB", "id": "Q9VWD0", "url": "https://www.uniprot.org/uniprotkb/Q9VWD0" } ], "pmid": "" }, { "name": "cell projection assembly", "id": "GO:0030031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030031", "evidence": [ { "database": "UniProtKB", "id": "Q9VWD0", "url": "https://www.uniprot.org/uniprotkb/Q9VWD0" } ], "pmid": "" }, { "name": "apposition of dorsal and ventral imaginal disc-derived wing surfaces", "id": "GO:0007475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007475", "evidence": [ { "database": "UniProtKB", "id": "Q9VWD0", "url": "https://www.uniprot.org/uniprotkb/Q9VWD0" } ], "pmid": "" }, { "name": "somatic muscle attachment to chitin-based cuticle", "id": "GO:0160175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160175", "evidence": [ { "database": "UniProtKB", "id": "Q9VWD0", "url": "https://www.uniprot.org/uniprotkb/Q9VWD0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 160, "end_pos": 162, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VWD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWD0" }, { "id": "PS50021", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50021" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Calponin-homology (CH)", "eco_id": "ECO_0000259", "start_pos": 90, "end_pos": 197, "start_aa": "Ile", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 160, "end_pos": 162 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VWD5-1", "uniprot_ac": "Q9VWD5", "uniprot_id": "Q9VWD5_DROME", "mass": { "chemical_mass": 55058.0, "monoisotopic_mass": 55058.0 }, "refseq": { "ac": "NP_001245766", "name": "uncharacterized protein, isoform B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245766" }, "gene_names": [ { "name": "Acbp8", "type": "recommended", "evidence": [ { "id": "Q9VWD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWD5" } ] }, { "name": "CG14232", "type": "synonym", "evidence": [ { "id": "NP_001245766", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245766" }, { "id": "Q9VWD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWD5" } ] }, { "name": "DmCG14232", "type": "synonym", "evidence": [ { "id": "NP_001245766", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245766" }, { "id": "Q9VWD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWD5" } ] }, { "name": "Dmel\\CG14232", "type": "synonym", "evidence": [ { "id": "NP_001245766", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245766" }, { "id": "Q9VWD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWD5" } ] }, { "name": "Dmel_CG14232", "type": "synonym", "evidence": [ { "id": "Q9VWD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWD5" } ] }, { "name": "anon-18DEc", "type": "synonym", "evidence": [ { "id": "NP_001245766", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245766" }, { "id": "Q9VWD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWD5" } ] } ], "protein_names": [ { "name": "Golgi resident protein GCP60", "type": "recommended", "evidence": [ { "id": "Q9VWD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWD5/entry#names_and_taxonomy" } ] }, { "name": "CG14232-PB", "type": "synonym", "evidence": [ { "id": "NP_001245766", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245766" } ] }, { "name": "uncharacterized protein, isoform B", "type": "synonym", "evidence": [ { "id": "NP_001245766", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245766" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VWD5", "url": "https://www.uniprot.org/uniprotkb/Q9VWD5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Acbp8", "url": "https://www.uniprot.org/uniprotkb/Q9VWD5", "locus": { "chromosome": "X", "start_pos": 19701927, "end_pos": 19704259, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0031061", "url": "https://www.ensemblgenomes.org/id/FBgn0031061" } ] } } ], "crossref": [ { "id": "FB:FBgn0031061", "url": "https://alliancegenome.org/gene/FB:FBgn0031061", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0031061", "url": "https://bgee.org/?page=gene&gene_id=FBgn0031061", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0031061", "url": "https://flybase.org/reports/FBgn0031061", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "32983", "url": "https://www.ncbi.nlm.nih.gov/gene/32983", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000582", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000582", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009038", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009038", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035984", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035984", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052269", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052269", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG14232", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG14232", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SYSIWRS", "url": "https://omabrowser.org/oma/group/SYSIWRS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VWD5", "url": "https://www.orthodb.org/?gene=Q9VWD5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22973", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22973", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22973:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22973:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00887", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00887", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13897", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13897", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001245766", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245766", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VWD5", "url": "https://www.uniprot.org/uniprotkb/Q9VWD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VWD5-1", "url": "https://www.uniprot.org/uniprotkb/Q9VWD5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASGTSGTSSSETAQSTDMAPSSAEKWGFPLIELYRLAFTFYKRNSGKAIHLSYEDNLKLIAFKQQAALGPFNTSRAPALGVLDVIGRDRQQHWQLLGEITREQAMEGFVDLLDTMCSAFRPYIEAVRQDRDETLRKELRLMEEKKEARERQENAQQELLEEGYKEELQRRQLQDALNKQTYQQFKLYAEKQFPGNPEQQAVLIHQLQREHYHQYMQQLHLQNQNQNQNQNTEDKGHQEAEHVPGNNNNSSTDLPNAMEGLKLGEVETQQHQQLAEQQDGHVEQTLEGVGQEQHGEEEYDDYVMICPAKIWTRPDIEQFKTEVSAGDGDGVITIGHGDTVTVRVPTNMNGKCIFWEFATDSYDIGFGIYFEWAKPVTNEVTVHVSDSDEDEDCVDEDYLSTTEDLESGSLSQERGAVNNPTAAPKAPISIIVPIYRRECYNEVYVGSHSYPGEGVYLLKFDNSYSIWRNKTLYYRVYYER", "length": 480, "header": "tr|Q9VWD5-1|Q9VWD5_DROME Isoform 1 of Golgi resident protein GCP60 OS=Drosophila melanogaster OX=7227 GN=Acbp8 PE=1 SV=1 CANONICAL=Q9VWD5-1" }, "isoforms": [ { "isoform_ac": "Q9VWD5-1", "url": "https://www.uniprot.org/uniprotkb/Q9VWD5/entry#Q9VWD5-1", "sequence": { "sequence": "MASGTSGTSSSETAQSTDMAPSSAEKWGFPLIELYRLAFTFYKRNSGKAIHLSYEDNLKLIAFKQQAALGPFNTSRAPALGVLDVIGRDRQQHWQLLGEITREQAMEGFVDLLDTMCSAFRPYIEAVRQDRDETLRKELRLMEEKKEARERQENAQQELLEEGYKEELQRRQLQDALNKQTYQQFKLYAEKQFPGNPEQQAVLIHQLQREHYHQYMQQLHLQNQNQNQNQNTEDKGHQEAEHVPGNNNNSSTDLPNAMEGLKLGEVETQQHQQLAEQQDGHVEQTLEGVGQEQHGEEEYDDYVMICPAKIWTRPDIEQFKTEVSAGDGDGVITIGHGDTVTVRVPTNMNGKCIFWEFATDSYDIGFGIYFEWAKPVTNEVTVHVSDSDEDEDCVDEDYLSTTEDLESGSLSQERGAVNNPTAAPKAPISIIVPIYRRECYNEVYVGSHSYPGEGVYLLKFDNSYSIWRNKTLYYRVYYER", "length": 480, "header": "tr|Q9VWD5-1|Q9VWD5_DROME Isoform 1 of Golgi resident protein GCP60 OS=Drosophila melanogaster OX=7227 GN=Acbp8 PE=1 SV=1 CANONICAL=Q9VWD5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VWD5", "url": "https://www.uniprot.org/uniprotkb/Q9VWD5" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VWD5", "url": "https://www.uniprot.org/uniprotkb/Q9VWD5" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWD5", "url": "https://www.uniprot.org/uniprotkb/Q9VWD5" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWD5", "url": "https://www.uniprot.org/uniprotkb/Q9VWD5" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VWD5", "url": "https://www.uniprot.org/uniprotkb/Q9VWD5" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VWD5", "url": "https://www.uniprot.org/uniprotkb/Q9VWD5" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VWD5", "url": "https://www.uniprot.org/uniprotkb/Q9VWD5" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWD5", "url": "https://www.uniprot.org/uniprotkb/Q9VWD5" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWD5", "url": "https://www.uniprot.org/uniprotkb/Q9VWD5" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VWD5", "url": "https://www.uniprot.org/uniprotkb/Q9VWD5" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VWD5", "url": "https://www.uniprot.org/uniprotkb/Q9VWD5" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG14232", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG14232", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A2R8QAR5-1", "protein_name": "Protein TMED8 isoform X1", "gene_name": "tmed8", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MCLEMEKLETSELQSRLSSLSVSSFPGITSKNCEANPLNRLQSTDLSQTVIPPDNQTKMDDNSNNQELSQSTEEPGSTLGKAEAGESQESSSSHPAEKKALPPMKPASTWTSVALKDLKTKLRQEKDSVVTVYRGDIMTVHVPTVPEAKRVCWEFATDGYDIGFGVYFDWSPVTSRAITVHISESSDDEDEDDELEGPVVPGDVEKGSKSSANTNLGEILPVYRQDSHLAVQGGSHDFPGEGTYLLKFDNSYSLWRNKTLYYRVYYSA", "length": 268 }, "evidence": [ { "id": "HGNC:18633", "url": "https://alliancegenome.org/gene/HGNC:18633#orthology", "database": "AGR" }, { "id": "MGI:1923480", "url": "https://alliancegenome.org/gene/MGI:1923480#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0YUV6-1", "protein_name": "Golgi resident protein GCP60", "gene_name": "ACBD3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAALSAERLEVSVDGLTLSPNAEAPPCEARPGHGDSAAGRNRAGPGCPSQAEAGGEEAAALSPERRWGFALEELYGLALRFFKEKDGKAFHPTYEEKLRLVALHKQVLLGPYNPDTCPEVGFFDVLGNDRRKEWAALGNMSKQEAMTEFVKLLNRCCHLFSTYVTSHKIEKEEQEKKRREEEERRRREEEELERLQKEEEKRRQEEEERLRREEEERRRIEEERLRMEQQKQQIMAALNSQTAMQFQQYAAQQYPGNYEQQQILIRQLQEQHYQQYMQQLYQVQLAQQQAALQKQQEAVVAAAGTPLTTASKVNVPAQGDMPSINGQASAHTDNPEKELDPEALEDALENGPKDSVPVIAAPSMWTRPQIKDFKEKIRQDADSVITVGRGEVVTVRVPTHEEGSYLFWEFATDSYDIGFGVYFEWTDSPNTAVSVHVSESSDDEDEEEENASSEEKAKKNANKPQLDEIVPVYRRDCHEEVYAGSHQYPGRGVYLLKFDNSYSLWRSKTVYYRVYYTR", "length": 519 }, "evidence": [ { "id": "Q9VWD5", "url": "https://omabrowser.org/oma/group/Q9VWD5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0AB32TAF6-1", "protein_name": "Golgi resident protein GCP60", "gene_name": "acbd3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MATEVQSGDLNSANSSRLEVSIDGLTLSPDSEGEQEQAETPDGQSAEQSHENPEQSVDGEEGEPTSSANIERKWGFALVELYGLALRFFKEKDGKAFHPTYKDKLRLVALHKQVLQGPYNPDASPEVGFFDVLGNDRRKEWASLGNMEKEESMLEFVRLLNKCCNLFAPFVASHKIEKEEQERKRREEEEQRRREEEEYERLRQEEERRRREEEERLRREEEERRQIEEERLRIEQQKQQIMAALNAQTAIQFQQYAAQQYPDSPEQQLILIRQLQEQHYQQYMQQLYQVQLAQQQAALQKQQEDAIVLSTLEASEVSAPCGEEVPTLNGQAESTTDSIERDQDLEPADEVTENGPTDSPPVIAAPSMWTRPQIKDFKVKIRQDVDSVITVGRGEVVTVRVPTHEEGSYLFWEFATDYYDIGFGVFFEWTDSTNASVSVHVSESSDEEEEEEDEKQQKCKYRHSEAQNSALTALQRNGEAQSEEEKAKKESGKPQVDEIVPVYRRDCHEEVYAGSHQYPGRGIYLLKFDNSYSLWRSKTVYYRVYYTR", "length": 548 }, "evidence": [ { "id": "Q9VWD5", "url": "https://omabrowser.org/oma/group/Q9VWD5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABK0M1P8-1", "protein_name": "GOLD domain-containing protein", "gene_name": "Tmed8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSDGQAAEGPAFWSPAARRGSAGGVGDRRGVEESQAAASEKEDLESTKVNSPLASAPDPAAQSSPYRPQMVSPVSKDTTEDLQKAAGASEAQAPGEQASLPAGQTQVLSEMAKYQAPQRPEDTVMIQSEHTGAIDVLSADLESADLLGDHRKVSPPLMAPPCVWTFAKVKEFKSKLGKEKNSRLVVKRGEVVTIRVPTHPEGKRVCWEFATDDYDIGFGVYFDWTPVTSTDITVQVSDSSEDEDEEEEEEEEIEEPVPVGDVERGSRSSLRGRYGEVMPVYRRDSHRDVQAGSHDYPGEGIYLLKFDNSYSLLRNKTLYFHIYYTS", "length": 326 }, "evidence": [ { "id": "HGNC:18633", "url": "https://alliancegenome.org/gene/HGNC:18633#orthology", "database": "AGR" }, { "id": "RGD:1589336", "url": "https://alliancegenome.org/gene/RGD:1589336#orthology", "database": "AGR" }, { "id": "MGI:1923480", "url": "https://alliancegenome.org/gene/MGI:1923480#orthology", "database": "AGR" }, { "id": "FB:FBgn0031061", "url": "https://alliancegenome.org/gene/FB:FBgn0031061#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MRE5-1", "protein_name": "Golgi resident protein GCP60", "gene_name": "ACBD3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAVLSAERLEVSVDGLTLSPDPEERPGAEGAPLLPPPLPPPSPPGSGRGPGAAGEQPEPGEAVAGGAAEEARRLEQRWGFGLEELYGLALRFFKEKDGKAFHPTYEEKLKLVALHKQVLMGPYNPDTCPEVGFFDVLGNDRRREWAALGNMSKEDAMVEFVKLLNRCCHLFSTYVASHKIEKEEQEKKRKEEEERRRREEEERERLQKEEEKRRREEEERLRREEEERRRLEEERLRLEQQKQQIMAALNSQTAVQFQQYAAQQYPGNYEQQQILIRQLQEQHYQQYMQQLYQVQLAQQQAALQKQQEVAVAGASSPTSSKVNATTPSDMMSVNGQAKTHTDNTEKETKPEAAEEALENGPKESLPVIAAPSMWTRPQIKDFKEKIRQDADSVITVGRGEVVTVRVPTHEEGSYLFWEFATDNYDIGFGVYFEWTDSPNTAVSVHVSESSDDDEEEEENISSEEKAKKNANKPLLDEIVPVYRRDCHEEVYAGSHQYPGRGVYLLKFDNSYSLWRSKSVYYRVYYTR", "length": 528 }, "evidence": [ { "id": "Q9VWD5", "url": "https://omabrowser.org/oma/group/Q9VWD5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3UHI4-1", "protein_name": "Protein TMED8", "gene_name": "Tmed8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDRQAAEGPAFWSPAARRGSAGGVGDRRGVEESQAAASEKEDLESTNVSSPLASASDPAAESSPYRPQMVSPASKDTTEDLQNVAGASEGQAPGEQAALPAGQTQVLSEMAKYQAPQRPEDTVMIQSEHTGAIDVLSADLESADLLGDHRKVSPPLMAPPCVWTFAKVKEFKSKLGKEKNSRLVVKRGEVVTIRVPTHPEGKRVCWEFATDDYDIGFGVYFDWTPVTSTDITVQVSDSSEDEEEEEDEEEEIEEPVPVGDVERGSRSSLRGRYGEVMPVYRRDSHRDVQAGSHDYPGEGIYLLKFDNSYSLLRNKTLYFHIYYTS", "length": 326 }, "evidence": [ { "id": "HGNC:18633", "url": "https://alliancegenome.org/gene/HGNC:18633#orthology", "database": "AGR" }, { "id": "RGD:1589336", "url": "https://alliancegenome.org/gene/RGD:1589336#orthology", "database": "AGR" }, { "id": "MGI:1923480", "url": "https://alliancegenome.org/gene/MGI:1923480#orthology", "database": "AGR" }, { "id": "FB:FBgn0031061", "url": "https://alliancegenome.org/gene/FB:FBgn0031061#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6PL24-1", "protein_name": "Protein TMED8", "gene_name": "TMED8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSDLQAAEGPGSWSPTARPGSAGGVGDCQGVEGSQAAASENEDLENKDTSLLASATDPEPCSSPHRPQMVSPVSKDATEDLRKATGPLEAQALVKQDLLPADQAQVLNEMAKYQVPQRSGDIVMIQSEHTGAIDVLSADLESADLLGDHRKVSPPLMAPPCIWTFAKVKEFKSKLGKEKNSRLVVKRGEVVTIRVPTHPEGKRVCWEFATDDYDIGFGVYFDWTPVTSTDITVQVSDSSDDEDEEEEEEEEIEEPVPAGDVERGSRSSLRGRYGEVMPVYRRDSHRDVQAGSHDYPGEGIYLLKFDNSYSLLRNKTLYFHIYYTS", "length": 325 }, "evidence": [ { "id": "HGNC:18633", "url": "https://alliancegenome.org/gene/HGNC:18633#orthology", "database": "AGR" }, { "id": "RGD:1589336", "url": "https://alliancegenome.org/gene/RGD:1589336#orthology", "database": "AGR" }, { "id": "MGI:1923480", "url": "https://alliancegenome.org/gene/MGI:1923480#orthology", "database": "AGR" }, { "id": "FB:FBgn0031061", "url": "https://alliancegenome.org/gene/FB:FBgn0031061#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TNY6-1", "protein_name": "Golgi resident protein GCP60", "gene_name": "Acbd3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAQLNVEQLEVSLDGLTLSPDSEERPGAEGAPLQTPPSSPPRDGLGSGTAGQQREPGEAAAEGAAEEARRMEQHWGFGLEELYGLALRFYKIKDGKAFHPTYEEKLKFVALHKQVLLGPYNPDTSPEVGFFDVLGNDRRREWAALGNMSKEDAMVEFVKLLNKCCPLLSAYVASHRIEKEEEEKRRKAEEERRQREEEERERLQKEEEKRKREEEDRLRREEEERRRIEEERLRLEQQKQQIMAALNSQTAVQFQQYAAQQYPGNYEQQQILIRQLQEQHYQQYMQQLYQVQLAQQQAALQKQQEVVVAGASLPASTKVNTAGASDPLPVNGQAKTHTENPEKVLEPEAAEEALENGPKDSLPVIAAPSMWTRPQIKDFKEKIRQDADSVITVRRGEVVTVRVPTHEEGSYLFWEFATDSYDIGFGVYFEWTDSPNAAVSVHVSESSDDEEEEEEENVTCEEKAKKNVNKPLLDEIVPVYRRDCHEEVYAGSHQYPGRGVYLLKFDNSYSLWRSKSVYYRVYYTR", "length": 526 }, "evidence": [ { "id": "HGNC:15453", "url": "https://alliancegenome.org/gene/HGNC:15453#orthology", "database": "AGR" }, { "id": "RGD:727851", "url": "https://alliancegenome.org/gene/RGD:727851#orthology", "database": "AGR" }, { "id": "MGI:2181074", "url": "https://alliancegenome.org/gene/MGI:2181074#orthology", "database": "AGR" }, { "id": "FB:FBgn0031061", "url": "https://alliancegenome.org/gene/FB:FBgn0031061#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BMP6-1", "protein_name": "Golgi resident protein GCP60", "gene_name": "Acbd3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAQLNVEQLEVSLDGLTLSPDSEERPGAEGAPPQTPPSSAPGNGLGSGASGQQREPGEAAAEGAAEEARRMEQHWGFGLEELYGLALRFYKIKDGKAFHPTYEEKLKFVALHKQVLLGPYNPDTSPEVGFFDVLGNDRRREWAALGNMSKEDAMVEFVKLLNKCCPLLSAYVASHRIEKEEEEKRRKAEEERRQREEEERERLQKEEEKRKREKEDRLRREEEERRRIEEERLRLEQQKQQIMAALNSQTAVQFQQYAAQQYPGNYEQQQILIRQLQEQHYQQYMQQLYQVQLAQQQAALQKQQEVVMAGASLPASSKVNTAGASDTLSVNGQAKTHTENSEKVLEPEAAEEALENGPKDSLPVIAAPSMWTRPQIKDFKEKIRQDADSVITVRRGEVVTVRVPTHEEGSYLFWEFATDSYDIGFGVYFEWTDSPNAAVSVHVSESSDEEEEEEENVTCEEKAKKNANKPLLDEIVPVYRRDCHEEVYAGSHQYPGRGVYLLKFDNSYSLWRSKSVYYRVYYTR", "length": 525 }, "evidence": [ { "id": "HGNC:15453", "url": "https://alliancegenome.org/gene/HGNC:15453#orthology", "database": "AGR" }, { "id": "RGD:727851", "url": "https://alliancegenome.org/gene/RGD:727851#orthology", "database": "AGR" }, { "id": "MGI:2181074", "url": "https://alliancegenome.org/gene/MGI:2181074#orthology", "database": "AGR" }, { "id": "FB:FBgn0031061", "url": "https://alliancegenome.org/gene/FB:FBgn0031061#orthology", "database": "AGR" }, { "id": "Q9VWD5", "url": "https://omabrowser.org/oma/group/Q9VWD5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H3P7-1", "protein_name": "Golgi resident protein GCP60", "gene_name": "ACBD3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAVLNAERLEVSVDGLTLSPDPEERPGAEGAPLLPPPLPPPSPPGSGRGPGASGEQPEPGEAAAGGAAEEARRLEQRWGFGLEELYGLALRFFKEKDGKAFHPTYEEKLKLVALHKQVLMGPYNPDTCPEVGFFDVLGNDRRREWAALGNMSKEDAMVEFVKLLNRCCHLFSTYVASHKIEKEEQEKKRKEEEERRRREEEERERLQKEEEKRRREEEERLRREEEERRRIEEERLRLEQQKQQIMAALNSQTAVQFQQYAAQQYPGNYEQQQILIRQLQEQHYQQYMQQLYQVQLAQQQAALQKQQEVVVAGSSLPTSSKVNATVPSNMMSVNGQAKTHTDSSEKELEPEAAEEALENGPKESLPVIAAPSMWTRPQIKDFKEKIQQDADSVITVGRGEVVTVRVPTHEEGSYLFWEFATDNYDIGFGVYFEWTDSPNTAVSVHVSESSDDDEEEEENIGCEEKAKKNANKPLLDEIVPVYRRDCHEEVYAGSHQYPGRGVYLLKFDNSYSLWRSKSVYYRVYYTR", "length": 528 }, "evidence": [ { "id": "HGNC:15453", "url": "https://alliancegenome.org/gene/HGNC:15453#orthology", "database": "AGR" }, { "id": "RGD:727851", "url": "https://alliancegenome.org/gene/RGD:727851#orthology", "database": "AGR" }, { "id": "MGI:2181074", "url": "https://alliancegenome.org/gene/MGI:2181074#orthology", "database": "AGR" }, { "id": "FB:FBgn0031061", "url": "https://alliancegenome.org/gene/FB:FBgn0031061#orthology", "database": "AGR" }, { "id": "Q9VWD5", "url": "https://omabrowser.org/oma/group/Q9VWD5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q9VWD5", "url": "https://www.uniprot.org/uniprotkb/Q9VWD5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "fatty-acyl-CoA binding", "id": "GO:0000062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000062", "evidence": [ { "database": "UniProtKB", "id": "Q9VWD5", "url": "https://www.uniprot.org/uniprotkb/Q9VWD5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 248, "end_pos": 250, "annotation": "n_glycosylation_sequon" }, { "start_pos": 249, "end_pos": 251, "annotation": "n_glycosylation_sequon" }, { "start_pos": 469, "end_pos": 471, "annotation": "n_glycosylation_sequon" }, { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VWD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWD5" }, { "id": "PS51228", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51228" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ACB", "eco_id": "ECO_0000259", "start_pos": 31, "end_pos": 122, "start_aa": "Leu", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q9VWD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWD5" }, { "id": "PS50866", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50866" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GOLD", "eco_id": "ECO_0000259", "start_pos": 316, "end_pos": 478, "start_aa": "Ile", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 248, "end_pos": 250 }, { "start_pos": 249, "end_pos": 251 }, { "start_pos": 469, "end_pos": 471 }, { "start_pos": 73, "end_pos": 75 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VWD8-1", "uniprot_ac": "Q9VWD8", "uniprot_id": "Q9VWD8_DROME", "mass": { "chemical_mass": 31744.0, "monoisotopic_mass": 31744.0 }, "refseq": { "ac": "NP_608345", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608345" }, "gene_names": [ { "name": "SPH158", "type": "recommended", "evidence": [ { "id": "Q9VWD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWD8" } ] }, { "name": "CG14227", "type": "synonym", "evidence": [ { "id": "NP_608345", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608345" }, { "id": "Q9VWD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWD8" } ] }, { "name": "Dmel\\CG14227", "type": "synonym", "evidence": [ { "id": "NP_608345", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608345" }, { "id": "Q9VWD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWD8" } ] }, { "name": "Dmel_CG14227", "type": "synonym", "evidence": [ { "id": "Q9VWD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWD8" } ] }, { "name": "SP158", "type": "synonym", "evidence": [ { "id": "NP_608345", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608345" }, { "id": "Q9VWD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWD8" } ] }, { "name": "SPH158", "type": "synonym", "evidence": [ { "id": "NP_608345", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608345" } ] } ], "protein_names": [ { "name": "Peptidase S1 domain-containing protein", "type": "recommended", "evidence": [ { "id": "Q9VWD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWD8/entry#names_and_taxonomy" } ] }, { "name": "CG14227-PB", "type": "synonym", "evidence": [ { "id": "NP_608345", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608345" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_608345", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608345" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VWD8", "url": "https://www.uniprot.org/uniprotkb/Q9VWD8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "SPH158", "url": "https://www.uniprot.org/uniprotkb/Q9VWD8", "locus": { "chromosome": "X", "start_pos": 19687791, "end_pos": 19688948, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0031058", "url": "https://www.ensemblgenomes.org/id/FBgn0031058" } ] } } ], "crossref": [ { "id": "FB:FBgn0031058", "url": "https://alliancegenome.org/gene/FB:FBgn0031058", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0031058", "url": "https://bgee.org/?page=gene&gene_id=FBgn0031058", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00190", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00190", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0031058", "url": "https://flybase.org/reports/FBgn0031058", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "32978", "url": "https://www.ncbi.nlm.nih.gov/gene/32978", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018114", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018114", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051487", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051487", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG14227", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG14227", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ANPWIVS", "url": "https://omabrowser.org/oma/group/ANPWIVS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VWD8", "url": "https://www.orthodb.org/?gene=Q9VWD8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24256", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24256", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_608345", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_608345", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VWD8", "url": "https://www.uniprot.org/uniprotkb/Q9VWD8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VWD8-1", "url": "https://www.uniprot.org/uniprotkb/Q9VWD8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKKVIAALLILFASLFLGSREGSAFLLDAECGRSLPTNAKLTWWNYFDSSTDIQANPWIVSVIVNGKAKCSGSLINHRFVLTAAHCVFREAMQVHLGDFDAWNPGQNCSSGARLSNAYCVRIDKKIVHAGFGKIQAQQYDIGLLRMQHAVQYSDFVRPICLLINEPVAAIDRFQLTVWGTTAEDFRSIPRVLKHSVGDRIDRELCTLKFQQQVDESQICVHTETSHACKGDSGGPFSAKILYGGTYRTFQFGIIIFGLSSCAGLSVCTNVTFYMDWIWDALVNLSA", "length": 286, "header": "tr|Q9VWD8-1|Q9VWD8_DROME Isoform 1 of Peptidase S1 domain-containing protein OS=Drosophila melanogaster OX=7227 GN=SPH158 PE=3 SV=2 CANONICAL=Q9VWD8-1" }, "isoforms": [ { "isoform_ac": "Q9VWD8-1", "url": "https://www.uniprot.org/uniprotkb/Q9VWD8/entry#Q9VWD8-1", "sequence": { "sequence": "MKKVIAALLILFASLFLGSREGSAFLLDAECGRSLPTNAKLTWWNYFDSSTDIQANPWIVSVIVNGKAKCSGSLINHRFVLTAAHCVFREAMQVHLGDFDAWNPGQNCSSGARLSNAYCVRIDKKIVHAGFGKIQAQQYDIGLLRMQHAVQYSDFVRPICLLINEPVAAIDRFQLTVWGTTAEDFRSIPRVLKHSVGDRIDRELCTLKFQQQVDESQICVHTETSHACKGDSGGPFSAKILYGGTYRTFQFGIIIFGLSSCAGLSVCTNVTFYMDWIWDALVNLSA", "length": 286, "header": "tr|Q9VWD8-1|Q9VWD8_DROME Isoform 1 of Peptidase S1 domain-containing protein OS=Drosophila melanogaster OX=7227 GN=SPH158 PE=3 SV=2 CANONICAL=Q9VWD8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VWD8", "url": "https://www.uniprot.org/uniprotkb/Q9VWD8" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VWD8", "url": "https://www.uniprot.org/uniprotkb/Q9VWD8" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWD8", "url": "https://www.uniprot.org/uniprotkb/Q9VWD8" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWD8", "url": "https://www.uniprot.org/uniprotkb/Q9VWD8" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VWD8", "url": "https://www.uniprot.org/uniprotkb/Q9VWD8" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VWD8", "url": "https://www.uniprot.org/uniprotkb/Q9VWD8" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VWD8", "url": "https://www.uniprot.org/uniprotkb/Q9VWD8" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWD8", "url": "https://www.uniprot.org/uniprotkb/Q9VWD8" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWD8", "url": "https://www.uniprot.org/uniprotkb/Q9VWD8" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE5", "url": "https://www.uniprot.org/uniprotkb/Q9VWE5" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE5", "url": "https://www.uniprot.org/uniprotkb/Q9VWE5" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE5", "url": "https://www.uniprot.org/uniprotkb/Q9VWE5" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE5", "url": "https://www.uniprot.org/uniprotkb/Q9VWE5" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE5", "url": "https://www.uniprot.org/uniprotkb/Q9VWE5" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE5", "url": "https://www.uniprot.org/uniprotkb/Q9VWE5" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE5", "url": "https://www.uniprot.org/uniprotkb/Q9VWE5" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE5", "url": "https://www.uniprot.org/uniprotkb/Q9VWE5" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE5", "url": "https://www.uniprot.org/uniprotkb/Q9VWE5" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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}, "synonyms": [ { "id": "DOID:1612", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1612", "name": "breast tumor", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1612", "name": "malignant neoplasm of breast", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1612", "name": "malignant tumor of the breast", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1612", "name": "mammary cancer", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1612", "name": "mammary tumor", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1612", "name": "primary breast cancer", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "hereditary breast carcinoma", "description": "Breast carcinoma that has developed in relatives of patients with history of breast carcinoma." }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer susceptibility, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, early-onset, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, invasive ductal, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, lobular, somatic", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, male, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, protection against, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, somatic", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial breast cancer", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial breast carcinoma", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial cancer of breast", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial cancer of the breast", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "hereditary breast cancer", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "hereditary breast carcinoma", "description": "" }, { "id": "MIM:114480", "resource": "MIM", "url": "https://www.omim.org/entry/114480", "name": "Breast cancer", "description": "Breast cancer" } ], "unlinked_id_list": [ "DOID:3017", "DOID:0050938" ], "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ] }, { "disease_id": "DOID:2671", "recommended_name": { "id": "DOID:2671", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2671", "name": "transitional cell carcinoma", "description": "A carcinoma that derives_from transitional epithelial cells." }, "synonyms": [ { "id": "DOID:2671", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2671", "name": "transitional carcinoma", "description": "" }, { "id": "DOID:2671", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2671", "name": "transitional cell tumor", "description": "" }, { "id": "DOID:2671", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2671", "name": "urothelial cell carcinoma", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "2671", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2671" } ] }, { "disease_id": "DOID:3908", "recommended_name": { "id": "DOID:3908", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma." }, "synonyms": [ { "id": "DOID:3908", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3908", "name": "NSCLC", "description": "" }, { "id": "DOID:3908", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3908", "name": "Non-small cell lung cancer", "description": "" }, { "id": "DOID:3908", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3908", "name": "non-small cell lung carcinoma", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ] }, { "disease_id": "DOID:5409", "recommended_name": { "id": "DOID:5409", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5409", "name": "lung small cell carcinoma", "description": "A lung carcinoma that has_material_basis_in primitive-appearing cells that are smaller than normal cells and is located_in the lung." }, "synonyms": [ { "id": "MONDO:0008433", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008433", "name": "small cell lung carcinoma", "description": "Small cell lung cancer (SCLC) is a highly aggressive malignant neoplasm, accounting for 10-15% of lung cancer cases, characterized byrapid growth, and early metastasis. SCLC usually manifests as a large hilar mass with bulky mediastinal lymphadenopathy presenting clinically with chest pain, persistent cough, dyspnea, wheezing, hoarseness, hemoptysis, loss of appetite, weight loss, and neurological and endocrine paraneoplastic syndromes. SCLC is primarily reported in elderly people with a history of long-term tobacco exposure." }, { "id": "MONDO:0008433", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008433", "name": "SCLC", "description": "" }, { "id": "MONDO:0008433", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008433", "name": "oat cell carcinoma", "description": "" }, { "id": "MONDO:0008433", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008433", "name": "oat cell carcinoma (morphologic abnormality)", "description": "" }, { "id": "MONDO:0008433", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008433", "name": "poorly differentiated endocrine neoplasm", "description": "" }, { "id": "MONDO:0008433", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008433", "name": "Small cell lung cancer", "description": "" }, { "id": "MONDO:0008433", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008433", "name": "lung oat cell carcinoma", "description": "" }, { "id": "MONDO:0008433", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008433", "name": "lung small cell carcinoma", "description": "" }, { "id": "MONDO:0008433", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008433", "name": "lung small cell neuroendocrine carcinoma", "description": "" }, { "id": "MONDO:0008433", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008433", "name": "oat cell carcinoma of lung", "description": "" }, { "id": "MONDO:0008433", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008433", "name": "oat cell carcinoma of the lung", "description": "" }, { "id": "MONDO:0008433", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008433", "name": "oat cell lung carcinoma", "description": "" }, { "id": "MONDO:0008433", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008433", "name": "small cell cancer of the lung, somatic", "description": "" }, { "id": "MONDO:0008433", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008433", "name": "small cell carcinoma of lung", "description": "" }, { "id": "MONDO:0008433", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008433", "name": "small cell carcinoma of the lung", "description": "" }, { "id": "MONDO:0008433", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008433", "name": "small cell lung cancer", "description": "" }, { "id": "MONDO:0008433", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008433", "name": "small cell neuroendocrine carcinoma of lung", "description": "" }, { "id": "MONDO:0008433", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008433", "name": "small cell neuroendocrine carcinoma of the lung", "description": "" }, { "id": "MONDO:0008433", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008433", "name": "small-cell cancer of lung", "description": "" }, { "id": "MONDO:0008433", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008433", "name": "SCLC1", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "5409", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5409" } ] }, { "disease_id": "DOID:5426", "recommended_name": { "id": "DOID:5426", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5426", "name": "primary ovarian insufficiency", "description": "An ovarian disease where ovaries do not produce estrogen despite high levels of circulating gonadotropins in women under 40." }, "synonyms": [ { "id": "DOID:5426", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5426", "name": "hypergonadotropic hypogonadism", "description": "" }, { "id": "DOID:5426", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5426", "name": "premature ovarian insufficiency", "description": "" }, { "id": "DOID:5426", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5426", "name": "premature ovarian failure", "description": "" }, { "id": "MONDO:0010706", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010706", "name": "premature ovarian failure 1", "description": "Any primary ovarian failure in which the cause of the disease is a mutation in the FMR1 gene." }, { "id": "MONDO:0010706", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010706", "name": "ovarian failure, premature", "description": "" }, { "id": "MONDO:0010706", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010706", "name": "FMR1 primary ovarian failure", "description": "" }, { "id": "MONDO:0010706", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010706", "name": "fragile x-associated primary ovarian insufficiency", "description": "" }, { "id": "MONDO:0010706", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010706", "name": "premature ovarian failure 1", "description": "" }, { "id": "MONDO:0010706", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010706", "name": "premature ovarian failure type 1", "description": "" }, { "id": "MONDO:0010706", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010706", "name": "primary ovarian failure caused by mutation in FMR1", "description": "" }, { "id": "MONDO:0010706", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010706", "name": "FMR1-related premature ovarian failure", "description": "" }, { "id": "MONDO:0010706", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010706", "name": "FMR1-related primary ovarian insufficiency", "description": "" }, { "id": "MONDO:0010706", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010706", "name": "Pof1", "description": "" }, { "id": "MONDO:0010706", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010706", "name": "familial premature ovarian failure", "description": "" }, { "id": "MONDO:0010706", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010706", "name": "fragile X-associated primary ovarian insufficiency", "description": "" }, { "id": "MONDO:0010706", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010706", "name": "idiopathic familial premature ovarian failure", "description": "" }, { "id": "MIM:311360", "resource": "MIM", "url": "https://www.omim.org/entry/311360", "name": "Premature ovarian failure 1", "description": "Premature ovarian failure 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "5426", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5426" } ] }, { "disease_id": "DOID:684", "recommended_name": { "id": "DOID:684", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver." }, "synonyms": [ { "id": "DOID:684", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:684", "name": "Hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma", "description": "A malignant tumor that arises from hepatocytes. Hepatocellular carcinoma is relatively rare in the United States but very common in all African countries south of the Sahara and in Southeast Asia. Most cases are seen in patients over the age of 50 years, but this tumor can also occur in younger individuals and even in children. Hepatocellular carcinoma is more common in males than females and is associated with hepatitis B, hepatitis C, chronic alcohol abuse and cirrhosis. Serum elevation of alpha-fetoprotein occurs in a large percentage of patients with hepatocellular carcinoma. Grossly, hepatocellular carcinoma may present as a single mass, as multiple nodules, or as diffuse liver involvement. Microscopically, there is a wide range of differentiation from tumor to tumor (well differentiated to poorly differentiated tumors). Hepatocellular carcinomas quickly metastasize to regional lymph nodes and lung. The overall median survival of untreated liver cell carcinoma is about 4 months. The most effective treatment of hepatocellular carcinoma is complete resection of the tumor. Lately, an increasing number of tumors have been treated with liver transplantation." }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "HCC", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "cancer, hepatocellular", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of liver", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of the liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma, hepatocellular, malignant", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatoblastoma, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular adenocarcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular cancer", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular cancer, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma, childhood type, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver cell cancer (hepatocellular carcinoma)", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver cell carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "primary carcinoma of liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "primary carcinoma of the liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "adult hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "adult primary hepatocellular carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma", "description": "A malignant tumor that arises from hepatocytes. Hepatocellular carcinoma is relatively rare in the United States but very common in all African countries south of the Sahara and in Southeast Asia. Most cases are seen in patients over the age of 50 years, but this tumor can also occur in younger individuals and even in children. Hepatocellular carcinoma is more common in males than females and is associated with hepatitis B, hepatitis C, chronic alcohol abuse and cirrhosis. Serum elevation of alpha-fetoprotein occurs in a large percentage of patients with hepatocellular carcinoma. Grossly, hepatocellular carcinoma may present as a single mass, as multiple nodules, or as diffuse liver involvement. Microscopically, there is a wide range of differentiation from tumor to tumor (well differentiated to poorly differentiated tumors). Hepatocellular carcinomas quickly metastasize to regional lymph nodes and lung. The overall median survival of untreated liver cell carcinoma is about 4 months. The most effective treatment of hepatocellular carcinoma is complete resection of the tumor. Lately, an increasing number of tumors have been treated with liver transplantation." }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "HCC", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "cancer, hepatocellular", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of liver", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of the liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma, hepatocellular, malignant", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatoblastoma, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular adenocarcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular cancer", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular cancer, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma, childhood type, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver cell cancer (hepatocellular carcinoma)", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver cell carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "primary carcinoma of liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "primary carcinoma of the liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "adult hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "adult primary hepatocellular carcinoma", "description": "" }, { "id": "MIM:114550", "resource": "MIM", "url": "https://www.omim.org/entry/114550", "name": "Hepatocellular carcinoma", "description": "Hepatocellular carcinoma" } ], "unlinked_id_list": [], "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ] }, { "disease_id": "DOID:9256", "recommended_name": { "id": "DOID:9256", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum." }, "synonyms": [ { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer", "description": "A primary or metastatic malignant neoplasm that affects the colon or rectum. Representative examples include carcinoma, lymphoma, and sarcoma." }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "cancer of colorectum", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "cancer of large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "cancer of large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "cancer of the large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colon cancer, advanced, somatic", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colon cancer, somatic", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer with chromosomal instability, somatic", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer, somatic", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectum cancer", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant colorectal neoplasm", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant colorectal tumor", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant colorectal tumour", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant colorectum neoplasm", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large bowel neoplasm", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large bowel tumor", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large bowel tumour", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large intestine neoplasm", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large intestine tumor", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large intestine tumour", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of colorectum", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of the large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of the large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumor of large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumor of large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumor of the large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumor of the large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumour of large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumour of large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumour of the large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumour of the large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "CRC", "description": "" }, { "id": "MIM:114500", "resource": "MIM", "url": "https://www.omim.org/entry/114500", "name": "Colorectal cancer", "description": "Colorectal cancer" } ], "unlinked_id_list": [], "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ] }, { "disease_id": "DOID:9538", "recommended_name": { "id": "DOID:9538", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9538", "name": "multiple myeloma", "description": "A myeloid neoplasm that is located_in the plasma cells in bone marrow." }, "synonyms": [ { "id": "DOID:9538", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9538", "name": "myeloma", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "plasma cell myeloma", "description": "A bone marrow-based plasma cell neoplasm characterized by a serum monoclonal protein and skeletal destruction with osteolytic lesions, pathological fractures, bone pain, hypercalcemia, and anemia. Clinical variants include non-secretory myeloma, smoldering myeloma, indolent myeloma, and plasma cell leukemia. (WHO, 2001)" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "Kahler disease", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "Kahler's disease", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "Multiple Myeloma", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "medullary plasmacytoma", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "multiple myeloma", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "multiple myeloma, resistance to, Somatic mutation", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "multiple myeloma, susceptibility to, Somatic mutation", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "multiple myeloma/plasma cell myeloma", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "myeloid neoplasm of plasma cell", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "myeloma", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "myeloma, multiple", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "myeloma, plasma cell, malignant", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "myelomatosis", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "plasma cell myeloid neoplasm", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "plasma cell myeloma", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "myeloma - multiple", "description": "" }, { "id": "MIM:254500", "resource": "MIM", "url": "https://www.omim.org/entry/254500", "name": "Multiple myeloma", "description": "Multiple myeloma" } ], "unlinked_id_list": [], "evidence": [ { "id": "9538", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9538" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VWE7", "url": "https://www.uniprot.org/uniprotkb/Q9VWE7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Ranbp21", "url": "https://www.uniprot.org/uniprotkb/Q9VWE7", "locus": { "chromosome": "X", "start_pos": 19646306, "end_pos": 19652269, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0031051", "url": "https://www.ensemblgenomes.org/id/FBgn0031051" } ] } } ], "crossref": [ { "id": "FB:FBgn0031051", "url": "https://alliancegenome.org/gene/FB:FBgn0031051", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0031051", "url": "https://bgee.org/?page=gene&gene_id=FBgn0031051", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0031051", "url": "https://flybase.org/reports/FBgn0031051", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "32970", "url": "https://www.ncbi.nlm.nih.gov/gene/32970", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001494", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001494", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045065", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045065", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG12234", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG12234", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IAKRSWG", "url": "https://omabrowser.org/oma/group/IAKRSWG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VWE7", "url": "https://www.orthodb.org/?gene=Q9VWE7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11223", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11223", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11223:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11223:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03810", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03810", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08389", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08389", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19273", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19273", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001285453", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285453", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VWE7", "url": "https://www.uniprot.org/uniprotkb/Q9VWE7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VWE7-1", "url": "https://www.uniprot.org/uniprotkb/Q9VWE7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSQHGGTEALAAELASAIDLVMNPMTQQQARLEAYMACERFKEESPMCAQVGLFLASSPQSNQQVRHFGLQLIEYTIKYRWNCITHEEKVYIKDNAIKMLNVGVGPAEDRSLLPTKDALSRIIVEMIKREWPQQWSDLLPELSQACTKGEAQTELVLLVFLRLVEDVALLQTIESNQRRKDMYQALNNNMNDIFEFFLRLVEQHVTAFRETTRLCNYTKANAHSRVVEMVLLTLSGFVEWVSIQHIMSSNGKLMHFLCILLNDKAFQCNAAECLAQITNRKGQTKERKPLLQLFNEEPLRYIYQASQIPADTSSTLAVEQHLNFLKKLLQVLNGMAQQLVALWGKDDATQRPVHLEVLLECLLLLVQHPSLGLSHGSALIWQLLLKHEPSSKDFAMVNYIPKLIHTIAPRIVKLPYPASASSPASLSTEAYIRLEHDSEEEYALYFFRCRTDFLEIFRLATLVQPLVTYGYCEQWLQQRLRNAQIEADAEVKSGNVSCSVLDPVYLEWDALVSVLDGVLSRILLVAERPSVPAGLRLLEECLKLETINPLTYSILLSCISALFVFLSMSACQITATNCVAMSGVSLLPRVLDKIFRALVMKPPNELEKVQAKSAKNLRRHAASLLVKLAHKYPLLLLPVFEQINGHVELLLKEPGKHQLCRLMRTTLQEALILISNHFCDFERQTLFIEHIVQDKRTEWLAFGDALKSPLDFMSFVGLDKPPIFAVEGAVTLQNRSRLLDALHVVLGVVKRCTWPDDPERAQRGGFVIGCTELGNPICRNPATKHIVPLLSHVLSLMRVLNELFAPEALQALSEGYRGIHGMMEHEKKLLMGICALPTDPLDTTIRSEPTAFEKMQTFMMMVTEGCYHLMGSAGPSLGRDLYQLMGLSDAIVTNVFSRMDLVPDYRLRPIIRVFFKPFVYSCPPSFYDSVLVPLFAHLAPLMCERLTRRWIYIASLYESGQLDGEVNDTQEVLEDQLNRTLTREYLDVLKIALVGGQIGADHVAAGANANSNSVAMENEEHSMDSAPQSRAIQSALLSDIISDLGGKLLRNGLIGNYVLMTLLKAIAWNDGMCSMKAVNIAAPVMRFLAAEKLMDENKAVTAFTAVLQGMQVHGQHEANQSGLVTLGVQFYELLRPQFPILSEVLQHIPSVNAADIQKFDEKIAVAPVKGNKVDRAKKDIFKKLTAQLVGRSVNQLFRHEVQIANLPPMQSHKAKGSMGTTADIMDSNQNASLARLFGPEK", "length": 1241, "header": "tr|Q9VWE7-1|Q9VWE7_DROME Isoform 1 of Ranbp21, isoform B OS=Drosophila melanogaster OX=7227 GN=Ranbp21 PE=1 SV=1 CANONICAL=Q9VWE7-1" }, "isoforms": [ { "isoform_ac": "Q9VWE7-1", "url": "https://www.uniprot.org/uniprotkb/Q9VWE7/entry#Q9VWE7-1", "sequence": { "sequence": "MSQHGGTEALAAELASAIDLVMNPMTQQQARLEAYMACERFKEESPMCAQVGLFLASSPQSNQQVRHFGLQLIEYTIKYRWNCITHEEKVYIKDNAIKMLNVGVGPAEDRSLLPTKDALSRIIVEMIKREWPQQWSDLLPELSQACTKGEAQTELVLLVFLRLVEDVALLQTIESNQRRKDMYQALNNNMNDIFEFFLRLVEQHVTAFRETTRLCNYTKANAHSRVVEMVLLTLSGFVEWVSIQHIMSSNGKLMHFLCILLNDKAFQCNAAECLAQITNRKGQTKERKPLLQLFNEEPLRYIYQASQIPADTSSTLAVEQHLNFLKKLLQVLNGMAQQLVALWGKDDATQRPVHLEVLLECLLLLVQHPSLGLSHGSALIWQLLLKHEPSSKDFAMVNYIPKLIHTIAPRIVKLPYPASASSPASLSTEAYIRLEHDSEEEYALYFFRCRTDFLEIFRLATLVQPLVTYGYCEQWLQQRLRNAQIEADAEVKSGNVSCSVLDPVYLEWDALVSVLDGVLSRILLVAERPSVPAGLRLLEECLKLETINPLTYSILLSCISALFVFLSMSACQITATNCVAMSGVSLLPRVLDKIFRALVMKPPNELEKVQAKSAKNLRRHAASLLVKLAHKYPLLLLPVFEQINGHVELLLKEPGKHQLCRLMRTTLQEALILISNHFCDFERQTLFIEHIVQDKRTEWLAFGDALKSPLDFMSFVGLDKPPIFAVEGAVTLQNRSRLLDALHVVLGVVKRCTWPDDPERAQRGGFVIGCTELGNPICRNPATKHIVPLLSHVLSLMRVLNELFAPEALQALSEGYRGIHGMMEHEKKLLMGICALPTDPLDTTIRSEPTAFEKMQTFMMMVTEGCYHLMGSAGPSLGRDLYQLMGLSDAIVTNVFSRMDLVPDYRLRPIIRVFFKPFVYSCPPSFYDSVLVPLFAHLAPLMCERLTRRWIYIASLYESGQLDGEVNDTQEVLEDQLNRTLTREYLDVLKIALVGGQIGADHVAAGANANSNSVAMENEEHSMDSAPQSRAIQSALLSDIISDLGGKLLRNGLIGNYVLMTLLKAIAWNDGMCSMKAVNIAAPVMRFLAAEKLMDENKAVTAFTAVLQGMQVHGQHEANQSGLVTLGVQFYELLRPQFPILSEVLQHIPSVNAADIQKFDEKIAVAPVKGNKVDRAKKDIFKKLTAQLVGRSVNQLFRHEVQIANLPPMQSHKAKGSMGTTADIMDSNQNASLARLFGPEK", "length": 1241, "header": "tr|Q9VWE7-1|Q9VWE7_DROME Isoform 1 of Ranbp21, isoform B OS=Drosophila melanogaster OX=7227 GN=Ranbp21 PE=1 SV=1 CANONICAL=Q9VWE7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE7", "url": "https://www.uniprot.org/uniprotkb/Q9VWE7" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE7", "url": "https://www.uniprot.org/uniprotkb/Q9VWE7" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE7", "url": "https://www.uniprot.org/uniprotkb/Q9VWE7" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE7", "url": "https://www.uniprot.org/uniprotkb/Q9VWE7" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE7", "url": "https://www.uniprot.org/uniprotkb/Q9VWE7" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE7", "url": "https://www.uniprot.org/uniprotkb/Q9VWE7" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE7", "url": "https://www.uniprot.org/uniprotkb/Q9VWE7" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE7", "url": "https://www.uniprot.org/uniprotkb/Q9VWE7" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE7", "url": "https://www.uniprot.org/uniprotkb/Q9VWE7" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE7", "url": "https://www.uniprot.org/uniprotkb/Q9VWE7" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VWE7", "url": "https://www.uniprot.org/uniprotkb/Q9VWE7" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG12234", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG12234", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZQE8-1", "protein_name": "Exportin-5", "gene_name": "Xpo5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEMEQVNALCEELVKAVTVMMDPSSTQRYRLEALKFCEEFKEKCPICVPCGLKLAEKTQIAIVRHFGLQILEHVVKFRWNSMSRLEKVYLKNSVMELIANGTLSILEEENHIKDVLSRIVVEMIKREWPQHWPDMLMELDTLSRQGETQRELVMFILLRLAEDVVTFQTLPTQRRRDIQQTLTQNMERILNFLLSTLQENVNKYQQMKTDASQEAEAQANCRVSIAALNTLAGYIDWVSLNHITAENCKLVETLCLLLNEQELQLGAAECLLIAVSRKGKLEDRKRLMILFGDVAMHYVLSAAQTADGGGLVEKHYLFLKRLCQVLCALGNLLCALLALDANIQTPVNFGMYLESFLAFTTHPSQFLRSSTHMTWGALFRHEVLSRDPSLLAVIPKYLRASMTNLVKMGFPSKTDSPSCEYSRFDFDSDEDFNAFFNSSRAQHGEVVRCVCRLDPKTSFQMAAEWLKYQLSAAIDTGPVNSCSTAGTGEGGFCSIFSPSYVQWEAMTFFLESVINQMFRTLEKEELPVNEGIELLQLVLNFEMKDPLILSCVLTNVSALFPFVTYKPAFLPQVFSKLFSFVTFESVGESKAPRTRAVRNVRRHACSSINKMCRDYPDLVLPNFDMLYSHVKQLLSNELLLTQMEKCALMEALVLVSNQFKDYERQKLFLEELMAPVVNIWLSEEMCRALSDIDAFIAYVGADLKSCDPAAQDPCGLNRARMSFCVYSILGVMRRTTWPSDLEEAKAGGFVVGYTPSGNPVFRNPCTEQILRLLDNLLALVRTHNTLYTPEMLTKMAEPFTKALDIVESEKTAILGLPQPLLEINDHPVYRTILERMQRFFGILYENCYHILGKAGPSMQQDFYTVEDLATQLLGSAFVNLNNIPDFRLRSMLHILKSRVFVKPLVLFCPPEHYETLISPILGPLFTYLHMRLSQKWHVINQRSVLCGEDEIAEDNPESQEMLEEQLVRMLTREVMDLIMACCVSKKTAEHTATPTADGDDEEMMATEVAPSSVVELTDLGKCLMKHEDVCTALLITAFNSLTWKDTLSCQRATTQLCWPLLKQVMSGTLLADAVTWLFTSVLKGLQMHGQHDGCMASLVHLAFQIYEALRPRYLEIRAVMEQIPEINKESLDQFDCKLLNPSLQKAADKRRKDHFKRLIAGCIGKPLGEQFRKEVHIKNLPWLFKKSKPMLETEVLDSEEGGLATIFEP", "length": 1209 }, "evidence": [ { "id": "RGD:1311522", "url": "https://alliancegenome.org/gene/RGD:1311522#orthology", "database": "AGR" }, { "id": "MGI:1913789", "url": "https://alliancegenome.org/gene/MGI:1913789#orthology", "database": "AGR" }, { "id": "HGNC:17675", "url": "https://alliancegenome.org/gene/HGNC:17675#orthology", "database": "AGR" }, { "id": "FB:FBgn0031051", "url": "https://alliancegenome.org/gene/FB:FBgn0031051#orthology", "database": "AGR" }, { "id": "SGD:S000002743", "url": "https://alliancegenome.org/gene/SGD:S000002743#orthology", "database": "AGR" }, { "id": "Q9VWE7", "url": "https://omabrowser.org/oma/group/Q9VWE7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P52918-1", "protein_name": "Protein MSN5", "gene_name": "MSN5", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDSTGASQIVSALDVIYSPKSNNSQRQEAQKFLDEVKLCSESPFWGYEIALQNPTNSILKYFGLGLLDHAVKKNWNDYDEGKRVALRKWVMELNFGVQDYDTRYIKEKLATLWVEVAKRTWGEALKQTNPTEEQLLTSWVDMDNNLFELWNINQSSRELALIIFRILFEDVFLLDDLIVLKRMTVIQPLCVMIVCPIEVFAIKYKFSDKWTKFKANEEGWFSVWIPELNNALQQNNSEYIIRLLETLKTCLNWPLTEVIVRNDVLSSLLTCLSSNIPRAQSMALDSIHILLTRPYSNESHYQMTIDRVFDNMDLLDSVYESLLFDPTDDIDETKYPIIKKFVDMISCLYVCVPKIKETNGQIQKYFKLVLKTTYNPSLIVSGLTLDLWCTCLRNDEYLPKLEKYVIPDLLQFAADALVYYEQIDGHISKKFAEIDFQSKSEFQTFCSTYRKRIRDIIRLISCVELDLTYDWLNNRLNNYFSSPFGQQVLSSTFLDHKLEPYLGALSQYMIVECFINGCIRWKIWYPTGDDYDEKLDSILQKLEILSNQLIALNLREPLLLKKQIQNFALFLTMLKDNVLFTLLEKIITSATMDYPEINLEERGAESDAVRDLRYACGIELNRMALLMPESLKKIYPDLESVIARIMPNLSYHEKISFKSFLLIIVLKSSLDMKEERFAAIVDPELLAWSDKTTVVGLSDLHWFMERLGIVQIAEYFQRRDIDENSDLLSIPIDDEGKELKSELTKRWQSLFPVRATRMFIHYSMQSIKTDEEFKMLQDLWRPRIVPILPYITRLLYQLQSYHDPDNWKGLPTVVQSFVKYSTIERFWEAGASNKSKDEFIDEHMKAMQTLRDFADSVGHIIRYTREYTLLVLSAISSLGSVFYLLDESPDLLLNSIAIFKPGSNEISPGVSTHGWKHIMNIAIRPILKGCPKDCLGKFMPAFLPKLFEILDLLLCQKWSSHMNDMDMNPVPTDDDQMTEEILEENLLRQLTTVVVRIVIDCVGQGNANPNSAKSRLNNHQMEMRKIIFNDLNTLAPFLKLLNHLISFKDTKCSFNSILVMKCCLTSVLNQNNTVDEYFTFEVMKNLLLNVLCNSAFKDSFHEALYAFTVIFLTLCKEYPSARAFLFEISNGYNIDELYRNLRSVDEYKTQRALMIDFIDWVKSTSGKEDGNVDHAGDERKRQEKREAILKKANERLIKKNKENGDMLDDPNIEDGAVGNLFDDN", "length": 1224 }, "evidence": [ { "id": "RGD:1311522", "url": "https://alliancegenome.org/gene/RGD:1311522#orthology", "database": "AGR" }, { "id": "MGI:1913789", "url": "https://alliancegenome.org/gene/MGI:1913789#orthology", "database": "AGR" }, { "id": "HGNC:17675", "url": "https://alliancegenome.org/gene/HGNC:17675#orthology", "database": "AGR" }, { "id": "FB:FBgn0031051", "url": "https://alliancegenome.org/gene/FB:FBgn0031051#orthology", "database": "AGR" }, { "id": "SGD:S000002743", "url": "https://alliancegenome.org/gene/SGD:S000002743#orthology", "database": "AGR" }, { "id": "Q9VWE7", "url": "https://omabrowser.org/oma/group/Q9VWE7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q0WP44-1", "protein_name": "Protein HASTY 1", "gene_name": "HST1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEDSNSTASNVARAILAVVDFSSTSDTRKSAVQFLDSVKSGDVRVLAKTSFHLVKKEWSSEIRLHAFKMLQHLVRLRWDELSPPECRGLVNLSIELMSEVANASENWPLKSQSAALVAEIVRREGPDRWQEIFTLLTSLSAQGPLQAELVLMTLRWLPEDITIYNDDLEGDRRRLLLRGLTQSLPEILPLLYNLLERHFGAAMSEAGMQHFDLAKQHADVVIACLNAIVAYTEWAPVPDLARYGILSGCSFLLSSSDFRLHACEVFKLVCSRKRPSDASTAEFDSAISNLFQILTNASREFLCRSSSSSSVIDDNDYDFAVCMCESMASLGSTNLQSISSDGGVMAVYLQQMLGFFQHFKLGLHFEALLFWLSLMRDLLPKPKAATYPSGGGSSTGGDDSSSQVDSEKKKTLSLINDDISSAILDVSFQRMLKKEKVPTGIALSLGPLELWSDEFEGKGDFGPYRSKLLELIKLTASHKPLISSTKISERVITLIKHLLASPAPLQHVAVMDSQQLALDCIVATLFDGSNEFAGGSSEVHYALRGIFEGLLQQLLSLKWNEPELMKVHVHYLDAMGPFLKYFPDAVGSLINKLFELLTSLPHVVKDPATSTSRAARLQICTSFIRIAKAAEKSVLPHMKGIADTMGYLAKEGTLLRGEHNILGEAFLVMASSAGAQQQQEVLAWLLEPLSQQWIQPEWQNNYLSDPMGLVRLCSNTSFMWSIYHTVTFFEKALKRSGYRKSNLNTTSATTPASHPMAHHLSWMLPPLLKLLRVLHSLWSPSVFQTLPPEMRAAMTMTDAERYSLLGEANPKLSKGVSVYADGSFEGTKEGQAEASESDIRNWLKGIRDCGYNVLGLSTTIGETFFKCLDANYVAMALMENLQSMEFRHIRLFIHTFITYIVKSCPADMWESWLGVLLHPLFIHCQQALSSAWPGLLQEGRAKVPDLFGIQSGSDMKLEVMEEKLLRDLTREIATLFSTMASPGLNTGVPVLEHSGHVGRVDMSTLTDLHAFRSNSMVGFLLNHKSVALPALQICLETFTWTDGEATTKVCYFCGVVVLLAKLTNNVELREFVSKDMFSAVIRGLGMESNAINSPDLVNICREIFIYLSDRDPAPRQVLLSLPCLTPNDLHAFEEATAKTSSPKEQKQLMRSLLLLGTGNNLKALAAQKSQNVITNVTARTRLPASAPETIGAGVLWDEEFVQ", "length": 1202 }, "evidence": [ { "id": "Q9VWE7", "url": "https://omabrowser.org/oma/group/Q9VWE7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q54PQ8-1", "protein_name": "Exportin-5", "gene_name": "xpo5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNDIILVVNQIEQALSLLHDPKSNNKQREESQVFLEEIKTRANAHSYAIAIITTSNNDILKHFALHIIETLVKNRWYECNDQERELIKKEILELMRRITSNEPKFIKEKLVTILVDVIKRDWPQRWMNLLTSLIEISKISDTQTELVLSTFGLLPHDIIFDTGSTSQVLSDQRRKDLMAGINLAVTSLFEYFYQLLESKYTQYKQPTPATTTTPQQTKQVIHLINVLLTTLRSYIEWVPSKVIFDHKLDQIFCQLILDVPFRMGACENLILFLGRKGRPDERIELIQTPFNFMENFLNSIKINSDFEDDYSFHKRITQALTILGTVHLNAYDDKHKIPNNYNIYLQLMLQMVSHPSILLSSFVLPFWHTFIKVESLELSYLEEVIKQIMETMLVKFVRIGDPEKSDSEQSKYSEIDFGTSKEWSNFFGGVRTRYLDIIKLITIQRREMAYIFIATKVADVLDALKANLNVASLSHEQTLVLESHSHILDSILLNIKDFTPESSLFFNKEQQQQPNIIQLTDRVLNLLFEINSTEPNITSFQIDCLQAYILYYQTNPESIKFLLNKIVPLIPFPGLDNPNRSFQNSVLHTRRRAISSLIGISTNISHLMKPYFDILYKSVVELFQKNVVTETEKVMLFHLLIVFSNNLPSYQQTLDFYKGILTPIIEQWVSLEMSTALSSPDAFIQYLGLSIADSQNLDATLVSRRKNIQYVASTLQIFWKKSQIPTNSSDELFAPFISNGISYNGKWPISSFVKQVLPGVLSLTRTLHQLWMPEHRAKIHPSLSTIFNLDDSITAPLLGFEYHKEQKSESSNVTFLRNILDCLRDACYEIVGYGFNHSDELFSLPDLPLVLLDSVFSYLESIENRHLKLLVKHILNYLIKNCPTKLEHTIFEPILPLLFSVLFNRIKAGWELIKLRSQKGEKENEKNEIVEDKILRDVSMEFLMCCSNIITQSPNYIFSSIDVMTPMVYGISSCLMAMDTPILKKSLIVSTQLLVDHEKVNDPKFFKLIGSEMFGCCIKILIVNKFAEFSNDIQSIIRLIYMKYYQICNYPQEILLSLPNITPPILQAFNKDLISTRSEKSQKVLFKKLLQDVIGIPLNKLKKESILDLPEKLFISKISDQSNENISNISNLFN", "length": 1135 }, "evidence": [ { "id": "Q9VWE7", "url": "https://omabrowser.org/oma/group/Q9VWE7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q924C1-1", "protein_name": "Exportin-5", "gene_name": "Xpo5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VWG0-1", "uniprot_ac": "Q9VWG0", "uniprot_id": "SHAWN_DROME", "mass": { "chemical_mass": 42167.0, "monoisotopic_mass": 42167.0 }, "refseq": { "ac": "NP_001027071", "name": "shawn, isoform D", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001027071" }, "gene_names": [ { "name": "Shawn", "type": "recommended", "evidence": [ { "id": "Q9VWG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWG0" } ] }, { "name": "CG14209", "type": "synonym", "evidence": [ { "id": "NP_001027071", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001027071" }, { "id": "Q9VWG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWG0" } ] }, { "name": "CG33075", "type": "synonym", "evidence": [ { "id": "NP_001027071", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001027071" } ] }, { "name": "Dmel\\CG14209", "type": "synonym", "evidence": [ { "id": "NP_001027071", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001027071" } ] }, { "name": "Shawn", "type": "synonym", "evidence": [ { "id": "NP_001027071", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001027071" } ] }, { "name": "sh", "type": "synonym", "evidence": [ { "id": "NP_001027071", "database": "RefSeq", "url": 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"https://www.ncbi.nlm.nih.gov/protein/NP_001027071" } ] }, { "name": "shawn, isoform D", "type": "synonym", "evidence": [ { "id": "NP_001027071", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001027071" } ] }, { "name": "shawn", "type": "synonym", "evidence": [ { "id": "NP_001027071", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001027071" } ] } ], "function": [ { "annotation": "Mitochondrial transporter required for glutathione import into mitochondria.", "evidence": [ { "database": "UniProtKB", "id": "Q9VWG0", "url": "https://www.uniprot.org/uniprotkb/Q9VWG0#function" }, { "database": "UniProtKB", "id": "Q9BZJ4", "url": "https://www.uniprot.org/uniprotkb/Q9BZJ4#function" } ] } ], "disease": [ { "disease_id": "DOID:1289", "recommended_name": { "id": "DOID:1289", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons." }, "synonyms": [ { "id": "DOID:1289", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1289", "name": "degenerative disease", "description": "" } ], "unlinked_id_list": [ "DOID:0112328", "DOID:0050953", "DOID:0111828", "DOID:0050765", "DOID:681", "DOID:0112322" ], "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ] } ], "snv": [], "mutagenesis": [ { "start_pos": 278, "end_pos": 278, "sequence_org": "G", "sequence_mut": "E", "comment": "Mutant flies show an accumulation of reactive oxygen species, mitochondrial dysfunction and neurodegeneration.", "evidence": [ { "database": "UniProtKB", "id": "Q9VWG0", "url": "https://www.uniprot.org/uniprotkb/Q9VWG0" }, { "database": "PubMed", "id": "26865615", "url": "https://glygen.org/publication/PubMed/26865615" } ] } ], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VWG0", "url": "https://www.uniprot.org/uniprotkb/Q9VWG0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Shawn", "url": "https://www.uniprot.org/uniprotkb/Q9VWG0", "locus": { "chromosome": "X", "start_pos": 19615617, "end_pos": 19611526, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0031039", "url": "https://www.ensemblgenomes.org/id/FBgn0031039" } ] } } ], "crossref": [ { "id": "FB:FBgn0031039", "url": "https://alliancegenome.org/gene/FB:FBgn0031039", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "Q9VWG0", "url": "https://alphafold.ebi.ac.uk/entry/Q9VWG0", "database": "AlphaFoldDB", "categories": [] }, { "id": "FBgn0031039", "url": "https://bgee.org/?page=gene&gene_id=FBgn0031039", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0031039", "url": "https://flybase.org/reports/FBgn0031039", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "3772641", "url": "https://www.ncbi.nlm.nih.gov/gene/3772641", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VWG0", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VWG0*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR018108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023395", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023395", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG14209", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG14209", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FVSPIEM", "url": "https://omabrowser.org/oma/group/FVSPIEM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VWG0", "url": "https://www.orthodb.org/?gene=Q9VWG0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45760", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45760", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45760:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45760:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00153", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00153", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q9VWG0", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q9VWG0", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001027071", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001027071", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VWG0", "url": "https://www.uniprot.org/uniprotkb/Q9VWG0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VWG0-1", "url": "https://www.uniprot.org/uniprotkb/Q9VWG0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATREACGQFAAASAAMAAASSQNPSKATMTDPRFRIRPLQQVASACTGAMVTACFMTPLDVIKTRLQAQQQALLSNKCFLYCNGLMDHICPCGPDTPNPAAAKPAPRFSGTIDAFIKISRTEGIGSLWSGLSPTLISALPSTIIYFVAYEQFKARFTDIHYKYTRRPDTIAHDIPHPIPFLVPLLAGVSGRILAVTCVSPVELIRTKMQSQRMTHAEMFGTIRQVVQSQGVLGLWRGLPPTILRDVPFSGIYWTCYEYLKSSFGVVEPTFSFSFAAGAISGSVAATITTPFDVVKTHEQIEFGEKFIFSDNPPKQVATKSVAMRLASIYRMGGVPAIFSGLGPRLFKVAPACAIMISSFEYGKSFFYHYNIDQHNRSNQATKGPGS", "length": 387, "header": "sp|Q9VWG0-1|SHAWN_DROME Isoform 1 of Solute carrier family 25 protein Shawn OS=Drosophila melanogaster OX=7227 GN=Shawn PE=1 SV=2 CANONICAL=Q9VWG0-1" }, "isoforms": [ { "isoform_ac": "Q9VWG0-1", "url": "https://www.uniprot.org/uniprotkb/Q9VWG0/entry#Q9VWG0-1", "sequence": { "sequence": "MATREACGQFAAASAAMAAASSQNPSKATMTDPRFRIRPLQQVASACTGAMVTACFMTPLDVIKTRLQAQQQALLSNKCFLYCNGLMDHICPCGPDTPNPAAAKPAPRFSGTIDAFIKISRTEGIGSLWSGLSPTLISALPSTIIYFVAYEQFKARFTDIHYKYTRRPDTIAHDIPHPIPFLVPLLAGVSGRILAVTCVSPVELIRTKMQSQRMTHAEMFGTIRQVVQSQGVLGLWRGLPPTILRDVPFSGIYWTCYEYLKSSFGVVEPTFSFSFAAGAISGSVAATITTPFDVVKTHEQIEFGEKFIFSDNPPKQVATKSVAMRLASIYRMGGVPAIFSGLGPRLFKVAPACAIMISSFEYGKSFFYHYNIDQHNRSNQATKGPGS", "length": 387, "header": "sp|Q9VWG0-1|SHAWN_DROME Isoform 1 of Solute carrier family 25 protein Shawn OS=Drosophila melanogaster OX=7227 GN=Shawn PE=1 SV=2 CANONICAL=Q9VWG0-1" }, "locus": { "chromosome": "X", "start_pos": 19611526, "end_pos": 19615617, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0074737", "url": "https://www.ensemblgenomes.org/id/FBtr0074737" }, { "database": "Ensembl Peptide", "id": "FBpp0074506", "url": "https://www.ensemblgenomes.org/id/FBpp0074506" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VWG0", "url": "https://www.uniprot.org/uniprotkb/Q9VWG0" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "A Drosophila full-length cDNA resource.", "journal": "Genome Biol.", "date": "2002", "authors": "Stapleton M, Carlson J, Brokstein P, Yu C, Champe M, George R, Guarin H, Kronmiller B, Pacleb J, Park S, Wan K, Rubin GM, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWG0", "url": "https://www.uniprot.org/uniprotkb/Q9VWG0" } ], "reference": [ { "type": "PubMed", "id": "12537569", "url": "https://glygen.org/publication/PubMed/12537569" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWG0", "url": "https://www.uniprot.org/uniprotkb/Q9VWG0" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "Shawn, the Drosophila Homolog of SLC25A39/40, Is a Mitochondrial Carrier That Promotes Neuronal Survival.", "journal": "The Journal of neuroscience : the official journal of the Society for Neuroscience", "date": "2016", "authors": "Slabbaert JR, Kuenen S, Swerts J, Maes I, Uytterhoeven V, Kasprowicz J, Fernandes AC, Blust R, Verstreken P", "evidence": [ { "database": "UniProtKB", "id": "Q9VWG0", "url": "https://www.uniprot.org/uniprotkb/Q9VWG0" } ], "reference": [ { "type": "PubMed", "id": "26865615", "url": "https://glygen.org/publication/PubMed/26865615" } ] } ], "pathway": [ { "id": "dme:Dmel_CG14209", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG14209", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P53320-1", "protein_name": "Mitochondrial carrier protein MTM1", "gene_name": "MTM1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSDRNTSNSLTLKERMLSAGAGSVLTSLILTPMDVVRIRLQQQQMIPDCSCDGAAEVPNAVSSGSKMKTFTNVGGQNLNNAKIFWESACFQELHCKNSSLKFNGTLEAFTKIASVEGITSLWRGISLTLLMAIPANMVYFSGYEYIRDVSPIASTYPTLNPLFCGAIARVFAATSIAPLELVKTKLQSIPRSSKSTKTWMMVKDLLNETRQEMKMVGPSRALFKGLEITLWRDVPFSAIYWSSYELCKERLWLDSTRFASKDANWVHFINSFASGCISGMIAAICTHPFDVGKTRWQISMMNNSDPKGGNRSRNMFKFLETIWRTEGLAALYTGLAARVIKIRPSCAIMISSYEISKKVFGNKLHQ", "length": 366 }, "evidence": [ { "id": "MGI:1196386", "url": "https://alliancegenome.org/gene/MGI:1196386#orthology", "database": "AGR" }, { "id": "MGI:2442486", "url": "https://alliancegenome.org/gene/MGI:2442486#orthology", "database": "AGR" }, { "id": "HGNC:24279", "url": "https://alliancegenome.org/gene/HGNC:24279#orthology", "database": "AGR" }, { "id": "HGNC:29680", "url": "https://alliancegenome.org/gene/HGNC:29680#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040718-52", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040718-52#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1250", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1250#orthology", "database": "AGR" }, { "id": "FB:FBgn0031039", "url": "https://alliancegenome.org/gene/FB:FBgn0031039#orthology", "database": "AGR" }, { "id": "RGD:1306193", "url": "https://alliancegenome.org/gene/RGD:1306193#orthology", "database": "AGR" }, { "id": "RGD:1308774", "url": "https://alliancegenome.org/gene/RGD:1308774#orthology", "database": "AGR" }, { "id": "SGD:S000003489", "url": "https://alliancegenome.org/gene/SGD:S000003489#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q498U3-1", "protein_name": "Mitochondrial glutathione transporter SLC25A40", "gene_name": "Slc25a40", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPETEGPPPTIQVTPLQQMMASCAGAVVTSLMVTPLDVVKIRLQAQNNPFPKGKCFLYSNGLMDHICICEEESKKAWYKKPGNFHGTLDAFLKIVRNEGIKSLWSGLPPTLVMAVPATVIYFTCYEQLSTFLKTKLGENETRIPIVAGIVARFGAVTMISPLELIRTKMQSKTFSYKELYQIVSMKVSEDGWISLWKGWAPTILRDVPFSAMYWYNYENLRRWLCEKSDLYESTFMINFTAGALSGSFAAVATLPFDVVKTQKQTQLWTHEYCKFPEPLDMSTWSIMKNIVADRGFSGLFTGLIPRLVKIVPACAIMISSYELGKGFFQQQNVESR", "length": 337 }, "evidence": [ { "id": "MGI:2442486", "url": "https://alliancegenome.org/gene/MGI:2442486#orthology", "database": "AGR" }, { "id": "HGNC:29680", "url": "https://alliancegenome.org/gene/HGNC:29680#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040718-52", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040718-52#orthology", "database": "AGR" }, { "id": "FB:FBgn0031039", "url": "https://alliancegenome.org/gene/FB:FBgn0031039#orthology", "database": "AGR" }, { "id": "RGD:1308774", "url": "https://alliancegenome.org/gene/RGD:1308774#orthology", "database": "AGR" }, { "id": "SGD:S000003489", "url": "https://alliancegenome.org/gene/SGD:S000003489#orthology", "database": "AGR" }, { "id": "Q9VWG0", "url": "https://omabrowser.org/oma/group/Q9VWG0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4V8K4-1", "protein_name": "Mitochondrial glutathione transporter SLC25A39", "gene_name": "Slc25a39", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDDQDPGGISPLQQMVASGAGAVVTSLFMTPLDVVKVRLQSQRPTVASELTTPSRFWSLSYTKSPSTLQSPGKCLLYCNGVLEPLYLCPNGTRCATWFQDPTRFTGTLDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGQSLTSDLYAPMVAGALARMGTVTVVSPLELVRTKLQAQHVSYRELAACVQAAVAQGGWRSLWLGWGPTALRDVPFSALYWFNYELVKSQLNGPRQKEQTSVGISFVAGGISGMVAATLTLPFDVVKTQRQMSLGAVEAMRVKPPRVDSTWLLLRRIQAESGTRGLFAGFLPRIIKAAPSCAIMISTYEFGKSFFHRLNQEQPLGH", "length": 359 }, "evidence": [ { "id": "MGI:1196386", "url": "https://alliancegenome.org/gene/MGI:1196386#orthology", "database": "AGR" }, { "id": "HGNC:24279", "url": "https://alliancegenome.org/gene/HGNC:24279#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1250", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1250#orthology", "database": "AGR" }, { "id": "FB:FBgn0031039", "url": "https://alliancegenome.org/gene/FB:FBgn0031039#orthology", "database": "AGR" }, { "id": "RGD:1306193", "url": "https://alliancegenome.org/gene/RGD:1306193#orthology", "database": "AGR" }, { "id": "SGD:S000003489", "url": "https://alliancegenome.org/gene/SGD:S000003489#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6DHC3-1", "protein_name": "Mitochondrial glutathione transporter SLC25A40", "gene_name": "slc25a40", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSCQESSPGPPGDITPFQQMMASCSGAIITSLLVTPLDVVKIRLQAQKNPFPKGKCFVYCNGLMDHICVCENGNTKVWYKAPGHFSGTLDAFLKIIRMEGIRSLWSGLPPTLIMAVPATVIYFTCYDQLFALLKLKMGDRSDLAPLFAGAIARVGSATVISPLELIRTKMQSEKQSYREMSAVIRSALKNEGLRSLWRGWGPTLLRDVPFSAMYWFNYEKGKWWLCKRYSCSEPTVAITFTAGALSGSIASIITLPFDVVKTKRQVEMGELQTMKLSTQVSSSTCSVMKRIVAENGVSGLFAGFMPRLIKVAPACAIMISTYEFGKAFFRKYNHQKEGQATASQHIISHTEKH", "length": 353 }, "evidence": [ { "id": "MGI:2442486", "url": "https://alliancegenome.org/gene/MGI:2442486#orthology", "database": "AGR" }, { "id": "HGNC:29680", "url": "https://alliancegenome.org/gene/HGNC:29680#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040718-52", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040718-52#orthology", "database": "AGR" }, { "id": "FB:FBgn0031039", "url": "https://alliancegenome.org/gene/FB:FBgn0031039#orthology", "database": "AGR" }, { "id": "RGD:1308774", "url": "https://alliancegenome.org/gene/RGD:1308774#orthology", "database": "AGR" }, { "id": "SGD:S000003489", "url": "https://alliancegenome.org/gene/SGD:S000003489#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q7SXW0-1", "protein_name": "Mitochondrial glutathione transporter SLC25A39", "gene_name": "slc25a39", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGDRPAVRISAAITPVQQMLASGTGAVLTSLFVTPLDVVKIRLQAQQTPLFQAIAAESRPWFRVTRPSKWKCFLYCNGLMDHVYVCQNMSSCSNLYKTSTHFSGTLDAFVKITHNEGLRSLWSGLPPTLVMAVPATVIYFTCYDQLRDFLCYSMGYHGDHIPLIAGGLARLGAVSVISPLELVRTKMQSRRLQYSELMVCIRSSVAQDGWLSLWRGWGPTVLRDVPFSALYWFNYELVKAQLCEHYRTPQASFTISFTAGAVSGAIAAVLTLPFDVVKTRRQIQLGEMEALGAVSMKKPSSTWNMMRNIWIDMGYKGLFAGFLPRVIKVAPACAVMISTYEFGKTFFQERNLHQARCGL", "length": 359 }, "evidence": [ { "id": "MGI:1196386", "url": "https://alliancegenome.org/gene/MGI:1196386#orthology", "database": "AGR" }, { "id": "HGNC:24279", "url": "https://alliancegenome.org/gene/HGNC:24279#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1250", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1250#orthology", "database": "AGR" }, { "id": "FB:FBgn0031039", "url": "https://alliancegenome.org/gene/FB:FBgn0031039#orthology", "database": "AGR" }, { "id": "RGD:1306193", "url": "https://alliancegenome.org/gene/RGD:1306193#orthology", "database": "AGR" }, { "id": "SGD:S000003489", "url": "https://alliancegenome.org/gene/SGD:S000003489#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8BGP6-1", "protein_name": "Mitochondrial glutathione transporter SLC25A40", "gene_name": "Slc25a40", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPETEGPPPTIPVTPLQQMIASCTGAVLTSLMVTPLDVVKIRLQAQNNPFPKGKCFLYSNGLMDHMCVCEEESKKAWYKKPGNFRGTLDAFLKILRNEGIKSLWSGLPPTLVMAIPATVIYFTCYEQLSAFLKTKLGENETRIPIVAGVVARFGAVTVISPLELIRTKVQSKKFSYKELYQFVSMRVSEDGWISLWKGWAPTILRDVPFSAMYWYNYENLKRWLCEKSGLYEPTFMINFTSGALSGSFAAVATLPFDVVKTQKQTQLWTNEYCKFPAPLDMSTWTIMKNIVADKGFSGLFTGLIPRLVKIVPACAIMISSYELGKSFFQKQNVESR", "length": 337 }, "evidence": [ { "id": "MGI:2442486", "url": "https://alliancegenome.org/gene/MGI:2442486#orthology", "database": "AGR" }, { "id": "HGNC:29680", "url": "https://alliancegenome.org/gene/HGNC:29680#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040718-52", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040718-52#orthology", "database": "AGR" }, { "id": "FB:FBgn0031039", "url": "https://alliancegenome.org/gene/FB:FBgn0031039#orthology", "database": "AGR" }, { "id": "RGD:1308774", "url": "https://alliancegenome.org/gene/RGD:1308774#orthology", "database": "AGR" }, { "id": "SGD:S000003489", "url": "https://alliancegenome.org/gene/SGD:S000003489#orthology", "database": "AGR" }, { "id": "Q9VWG0", "url": "https://omabrowser.org/oma/group/Q9VWG0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IQW4-1", "protein_name": "Tyler, isoform B", "gene_name": "Tyler", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPPQLMSQMENGGEEEGCRLECKEMDPLRLTTLILSADPRYRIKPMQQVVSALVGGLITTFVVTPLEVVKTRVQTQHAIRQRPTVSKLCYVYHNGLMTHVCRSSDICVPKPGRDPQNLRPLRGAMDAFVKIVCTSGFSGLWAGLSPTLVSALPSTIIYFLTYEYIKNSLSHIYLVSQKFEESGMKDQVPGADGGDPLDQATRGINVSATAPVSTASLPYYVPMASGICSRTIVVTAITPIEMVRIKMQSEYMTYAELWRVLRSLIRQHGILGLWRGWPPTVMRDAPFSGTYWAVYEAIKRAFSVTEPTFLFSFLTGAISGAVATFVTMPFDLITTHTQIELGQDVLYEEIGAGTGAGTGTGAGARPKTPQSAVANSRPSVLSRMRQIYRLQGVRGLYVGVMPRMLRVVPACAIMISTFEYSKSFFFHYNLDLQEAAYRRSQ", "length": 441 }, "evidence": [ { "id": "MGI:2442486", "url": "https://alliancegenome.org/gene/MGI:2442486#orthology", "database": "AGR" }, { "id": "HGNC:24279", "url": "https://alliancegenome.org/gene/HGNC:24279#orthology", "database": "AGR" }, { "id": "HGNC:29680", "url": "https://alliancegenome.org/gene/HGNC:29680#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040718-52", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040718-52#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1250", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1250#orthology", "database": "AGR" }, { "id": "RGD:1308774", "url": "https://alliancegenome.org/gene/RGD:1308774#orthology", "database": "AGR" }, { "id": "SGD:S000003489", "url": "https://alliancegenome.org/gene/SGD:S000003489#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8TBP6-1", "protein_name": "Mitochondrial glutathione transporter SLC25A40", "gene_name": "SLC25A40", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPETRGQEIIKVTPLQQMLASCTGAILTSVIVTPLDVVKIRLQAQNNPLPKGKCFVYSNGLMDHLCVCEEGGNKLWYKKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLGENETCIPIVAGIVARFGAVTVISPLELIRTKMQSKKFSYVELHRFVSKKVSEDGWISLWRGWAPTVLRDVPFSAMYWYNYEILKKWLCEKSGLYEPTFMINFTSGALSGSFAAVATLPFDVVKTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLFSGLIPRLIKIAPACAIMISTYEFGKAFFQKQNVRRQQY", "length": 338 }, "evidence": [ { "id": "MGI:2442486", "url": "https://alliancegenome.org/gene/MGI:2442486#orthology", "database": "AGR" }, { "id": "HGNC:29680", "url": "https://alliancegenome.org/gene/HGNC:29680#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040718-52", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040718-52#orthology", "database": "AGR" }, { "id": "FB:FBgn0031039", "url": "https://alliancegenome.org/gene/FB:FBgn0031039#orthology", "database": "AGR" }, { "id": "RGD:1308774", "url": "https://alliancegenome.org/gene/RGD:1308774#orthology", "database": "AGR" }, { "id": "SGD:S000003489", "url": "https://alliancegenome.org/gene/SGD:S000003489#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9BZJ4-1", "protein_name": "Mitochondrial glutathione transporter SLC25A39", "gene_name": "SLC25A39", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADQDPAGISPLQQMVASGTGAVVTSLFMTPLDVVKVRLQSQRPSMASELMPSSRLWSLSYTKLPSSLQSTGKCLLYCNGVLEPLYLCPNGARCATWFQDPTRFTGTMDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPMVAGALARLGTVTVISPLELMRTKLQAQHVSYRELGACVRTAVAQGGWRSLWLGWGPTALRDVPFSALYWFNYELVKSWLNGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYEFGKSFFQRLNQDRLLGG", "length": 359 }, "evidence": [ { "id": "MGI:1196386", "url": "https://alliancegenome.org/gene/MGI:1196386#orthology", "database": "AGR" }, { "id": "HGNC:24279", "url": "https://alliancegenome.org/gene/HGNC:24279#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1250", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1250#orthology", "database": "AGR" }, { "id": "FB:FBgn0031039", "url": "https://alliancegenome.org/gene/FB:FBgn0031039#orthology", "database": "AGR" }, { "id": "RGD:1306193", "url": "https://alliancegenome.org/gene/RGD:1306193#orthology", "database": "AGR" }, { "id": "SGD:S000003489", "url": "https://alliancegenome.org/gene/SGD:S000003489#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D8K8-1", "protein_name": "Mitochondrial glutathione transporter SLC25A39", "gene_name": "Slc25a39", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDDQDPGGISPLQQMVASGAGAVVTSLFMTPLDVVKVRLQSQRPSATSELTTPSRFWSLSYTKSSSALQSPGKCLLYCNGVLEPLYLCPNGTRCATWFQDPTRFTGTLDAFVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGQSLTSDLYAPMVAGALARMGTVTVVSPLELVRTKLQAQHVSYRELASSVQAAVTQGGWRSLWLGWGPTALRDVPFSALYWFNYELVKSWLSGLRPKDQTSVGISFVAGGISGMVAATLTLPFDVVKTQRQMSLGAVEAVRVKPPRVDSTWLLLRRIRAESGTRGLFAGFLPRIIKAAPSCAIMISTYEFGKSFFQRLNQEQPLGR", "length": 359 }, "evidence": [ { "id": "MGI:1196386", "url": "https://alliancegenome.org/gene/MGI:1196386#orthology", "database": "AGR" }, { "id": "HGNC:24279", "url": "https://alliancegenome.org/gene/HGNC:24279#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1250", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1250#orthology", "database": "AGR" }, { "id": "FB:FBgn0031039", "url": "https://alliancegenome.org/gene/FB:FBgn0031039#orthology", "database": "AGR" }, { "id": "RGD:1306193", "url": "https://alliancegenome.org/gene/RGD:1306193#orthology", "database": "AGR" }, { "id": "SGD:S000003489", "url": "https://alliancegenome.org/gene/SGD:S000003489#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VI05-1", "protein_name": "Solute carrier family 25 member 40", "gene_name": "Dmel\\CG2616", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSKEDSGASSAEANPAESEISMGRGPRPRSFTGGGGGGGTGGSGGSGGTSGGNNLKPERSAREDDAINRLTDSKSSHRKLLSDPRFQIRPLQQVISACTGAMITACFMTPLDVIKTRMQSQQSPAHKCFFYSNGLMDHLFASGPNGSELASLRQRPQFSSSWDALMKISRHEGLAALWSGLGPTLVSALPSTIIYFVAYEQFKARYLQIYESHYNKSQEPRHLEIRDTKKSLPSVVPMMSGVTARICAVTVVSPIELVRTKMQAQRQTYAQMLQFVRSVVALQGVWGLWRGLRPTILRDVPFSGIYWPIYESLKQNLGHGSQPSFSLSFLAGVMAGTVAAIVTTPFDVVKTHEQIEFGERVIFTDSPARDFGKKSTFSRLTGIYRTHGVRGLFAGCGPRLLKVAPACAIMISTFEYSKSFFFHYNVRHHNEALLLDNPKDTTVEDDDIE", "length": 449 }, "evidence": [ { "id": "MGI:1196386", "url": "https://alliancegenome.org/gene/MGI:1196386#orthology", "database": "AGR" }, { "id": "MGI:2442486", "url": "https://alliancegenome.org/gene/MGI:2442486#orthology", "database": "AGR" }, { "id": "HGNC:24279", "url": "https://alliancegenome.org/gene/HGNC:24279#orthology", "database": "AGR" }, { "id": "HGNC:29680", "url": "https://alliancegenome.org/gene/HGNC:29680#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040718-52", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040718-52#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1250", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1250#orthology", "database": "AGR" }, { "id": "RGD:1306193", "url": "https://alliancegenome.org/gene/RGD:1306193#orthology", "database": "AGR" }, { "id": "RGD:1308774", "url": "https://alliancegenome.org/gene/RGD:1308774#orthology", "database": "AGR" }, { "id": "SGD:S000003489", "url": "https://alliancegenome.org/gene/SGD:S000003489#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9VWG0", "url": "https://www.uniprot.org/uniprotkb/Q9VWG0" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q9VWG0", "url": "https://www.uniprot.org/uniprotkb/Q9VWG0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "Q9VWG0", "url": "https://www.uniprot.org/uniprotkb/Q9VWG0" } ], "pmid": "" }, { "name": "glutathione transmembrane transporter activity", "id": "GO:0034634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034634", "evidence": [ { "database": "UniProtKB", "id": "Q9VWG0", "url": "https://www.uniprot.org/uniprotkb/Q9VWG0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mitochondrial transmembrane transport", "id": "GO:1990542", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990542", "evidence": [ { "database": "UniProtKB", "id": "Q9VWG0", "url": "https://www.uniprot.org/uniprotkb/Q9VWG0" } ], "pmid": "" }, { "name": "glutathione import into mitochondrion", "id": "GO:0160007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160007", "evidence": [ { "database": "UniProtKB", "id": "Q9VWG0", "url": "https://www.uniprot.org/uniprotkb/Q9VWG0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 376, "end_pos": 378, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "AF-Q9VWG0-F1", "pdb_chain": "global", "start_pos": 1, "end_pos": 387, "overlap": "1.0", "method": "AlphaFold", "type": "alphafold", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/AF-Q9VWG0-F1.pdb", "url_external": "https://alphafold.ebi.ac.uk/entry/Q9VWG0" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 376, "end_pos": 378 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { 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"CG14220-PB", "type": "synonym", "evidence": [ { "id": "NP_001245759", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245759" } ] }, { "name": "uncharacterized protein, isoform B", "type": "synonym", "evidence": [ { "id": "NP_001245759", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245759" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VWG2", "url": "https://www.uniprot.org/uniprotkb/Q9VWG2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "SDS3", "url": "https://www.uniprot.org/uniprotkb/Q9VWG2", "locus": { "chromosome": "X", "start_pos": 19599803, "end_pos": 19601851, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0031036", "url": "https://www.ensemblgenomes.org/id/FBgn0031036" } ] } } ], "crossref": [ { "id": "FB:FBgn0031036", "url": "https://alliancegenome.org/gene/FB:FBgn0031036", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0031036", "url": "https://bgee.org/?page=gene&gene_id=FBgn0031036", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0031036", "url": "https://flybase.org/reports/FBgn0031036", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "32954", "url": "https://www.ncbi.nlm.nih.gov/gene/32954", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG14220", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG14220", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YERRWYH", "url": "https://omabrowser.org/oma/group/YERRWYH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VWG2", "url": "https://www.orthodb.org/?gene=Q9VWG2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21964", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21964", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08598", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08598", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-3214815", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-3214815", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-5689880", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-5689880", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001245759", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245759", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VWG2", "url": "https://www.uniprot.org/uniprotkb/Q9VWG2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VWG2-1", "url": "https://www.uniprot.org/uniprotkb/Q9VWG2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSNYYSLLLQADTYDDESIGDERSEEDTDDASETEFRSPSRYGAMNGTSNSNNMGTNSELKEQMYQHKLFNLQKQMEELGQLVHPEYLKRVKKLDSQLKERRRMNEVYKEYMRECVERDYVLEKMAAQKEYDEKMMDLKDNLISDFEDRKRQIENERFSIELTNDSMEIKTTITRKLRRRPNEPLPVIEKRRKPATGQLLVYQLDDKEIESDLKIIQRGRPNPVPQQNGSGSYGSGSQQQQSMHVLAEPTSNSGLVETRIEDNKLLYERRWFCRGQQVYVEGKEMSKFAATITAIGNEVVWVKRTNETKVKINMSHLAKGKISIKRR", "length": 327, "header": "tr|Q9VWG2-1|Q9VWG2_DROME Isoform 1 of Sin3 histone deacetylase corepressor complex component SDS3 OS=Drosophila melanogaster OX=7227 GN=SDS3 PE=4 SV=1 CANONICAL=Q9VWG2-1" }, "isoforms": [ { "isoform_ac": "Q9VWG2-1", "url": "https://www.uniprot.org/uniprotkb/Q9VWG2/entry#Q9VWG2-1", "sequence": { "sequence": "MSNYYSLLLQADTYDDESIGDERSEEDTDDASETEFRSPSRYGAMNGTSNSNNMGTNSELKEQMYQHKLFNLQKQMEELGQLVHPEYLKRVKKLDSQLKERRRMNEVYKEYMRECVERDYVLEKMAAQKEYDEKMMDLKDNLISDFEDRKRQIENERFSIELTNDSMEIKTTITRKLRRRPNEPLPVIEKRRKPATGQLLVYQLDDKEIESDLKIIQRGRPNPVPQQNGSGSYGSGSQQQQSMHVLAEPTSNSGLVETRIEDNKLLYERRWFCRGQQVYVEGKEMSKFAATITAIGNEVVWVKRTNETKVKINMSHLAKGKISIKRR", "length": 327, "header": "tr|Q9VWG2-1|Q9VWG2_DROME Isoform 1 of Sin3 histone deacetylase corepressor complex component SDS3 OS=Drosophila melanogaster OX=7227 GN=SDS3 PE=4 SV=1 CANONICAL=Q9VWG2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VWG2", "url": "https://www.uniprot.org/uniprotkb/Q9VWG2" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VWG2", "url": "https://www.uniprot.org/uniprotkb/Q9VWG2" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWG2", "url": "https://www.uniprot.org/uniprotkb/Q9VWG2" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWG2", "url": "https://www.uniprot.org/uniprotkb/Q9VWG2" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VWG2", "url": "https://www.uniprot.org/uniprotkb/Q9VWG2" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VWG2", "url": "https://www.uniprot.org/uniprotkb/Q9VWG2" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VWG2", "url": "https://www.uniprot.org/uniprotkb/Q9VWG2" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWG2", "url": "https://www.uniprot.org/uniprotkb/Q9VWG2" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWG2", "url": "https://www.uniprot.org/uniprotkb/Q9VWG2" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VWG2", "url": "https://www.uniprot.org/uniprotkb/Q9VWG2" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VWG2", "url": "https://www.uniprot.org/uniprotkb/Q9VWG2" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], 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Kekkon 5, isoform B OS=Drosophila melanogaster OX=7227 GN=kek5 PE=1 SV=2 CANONICAL=Q9VWI6-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 33, "start_aa": "Thr", "end_pos": 33, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr33", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 793, "start_aa": "Thr", "end_pos": 793, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr793", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VWI6", "url": "https://www.uniprot.org/uniprotkb/Q9VWI6" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VWI6", "url": "https://www.uniprot.org/uniprotkb/Q9VWI6" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWI6", "url": "https://www.uniprot.org/uniprotkb/Q9VWI6" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWI6", "url": "https://www.uniprot.org/uniprotkb/Q9VWI6" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VWI6", "url": "https://www.uniprot.org/uniprotkb/Q9VWI6" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VWI6", "url": "https://www.uniprot.org/uniprotkb/Q9VWI6" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VWI6", "url": "https://www.uniprot.org/uniprotkb/Q9VWI6" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWI6", "url": "https://www.uniprot.org/uniprotkb/Q9VWI6" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWI6", "url": "https://www.uniprot.org/uniprotkb/Q9VWI6" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VWI6", "url": "https://www.uniprot.org/uniprotkb/Q9VWI6" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VWI6", "url": "https://www.uniprot.org/uniprotkb/Q9VWI6" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], 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"https://alliancegenome.org/gene/RGD:1564668#orthology", "database": "AGR" }, { "id": "FB:FBgn0031016", "url": "https://alliancegenome.org/gene/FB:FBgn0031016#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q504C1-1", "protein_name": "Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 2", "gene_name": "lrit2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDVCVLFHLIVFCILISHISSECFPGCSCGTDRHGRSLTCMETALTGIPDGLPEDLTKIRIEKSQLSELPEAVFSHVKALKHLWLNFNDIAIINIKSLEGLANLTELRLQGNKLRSVPWTAFEETPNLKILDLKHNRIDALPEHALKFLPGLTYLDLSSNQLSVISKDVFLNWPLYHSENKHEKPSASNVVLALHDNPWLCDCRLGGFIEFIKSLTPPFILMNSYLTCSSPELKAGRFFHEVDLKTCVKPVVSAPVITITAPLGGNVTLTCSASARPEAVIRWIYALKMLRGFRDILSHVDEDTISSQLVIPSLHSADRGLYTCIANNFLGNSSVIISVDVKSPEGSSSHPSGPSAAIGEENVYIDIRIAKQTVYGITIEWRAVTENPAETWFTIHFGRYDAVKKEQIYIGPGINTYSVTDLLPATKYEICVTLKNQAPRIGQCIVFVTGSDFNEMEQREKLIHIVVIVLAMVLAVPAGMYACTTDAKFNCFERCAELWRNRRHAELSNPTGDRQGTFDSLQAASDEGLYKESNKDKKARRRSAEKIHKTKNDRRPTAELY", "length": 561 }, "evidence": [ { "id": "HGNC:23443", "url": "https://alliancegenome.org/gene/HGNC:23443#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050522-160", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-160#orthology", "database": "AGR" }, { "id": "MGI:2444885", "url": "https://alliancegenome.org/gene/MGI:2444885#orthology", "database": "AGR" }, { "id": "RGD:1564668", "url": "https://alliancegenome.org/gene/RGD:1564668#orthology", "database": "AGR" }, { "id": "FB:FBgn0031016", "url": "https://alliancegenome.org/gene/FB:FBgn0031016#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6PFC5-1", "protein_name": "Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 2", "gene_name": "Lrit2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFVFYCFLQVLVSWVIHAVQPFCLPECTCSEESFGRSLQCMSMSLGKIPDNFPEELKQVRIENSPLFELSQGFFTNMSSLEYLWLNFNNVTVIHLGALEDLPELRELRLEGNKLRSVPWTAFRATPLLRVLDLKHNRIDSVPELALQFLTNLIYLDISSNRLTVVSKGVFLNWPAYQKRQQLGCGAEFLSNMVLSLHNNPWLCDCRLRGLAQFVKSVGPPFILVNSYLVCQGPVSKAGQLLHETELGVCMKPTISTPSVNVTIQVGKNVTLQCFAQASPSPTIAWKYPLSTWREFDVLASPIAEGIILSQLVIPAAQLVDGGNYTCMAFNSIGRSSLVILLYVQPAQAMPGLHFLSTSSEVSAYVDLRVVKQTVHGILLQWLTVTNLAEEQWFTLYITSDEALRKKVVHIGPGINTYAVDDLLPATKYKACLSLRNQPPSQGQCVVFVTGKDSGGLEGREHLLHVTVVLCAVLLALPVGAYVWVSQGPYNFSEWCWRRCPLHRKTLRCPQAVPQCKDNSFKDPSGVYEDGESHRVMEEDEEVEKEGIS", "length": 549 }, "evidence": [ { "id": "HGNC:23443", "url": "https://alliancegenome.org/gene/HGNC:23443#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050522-160", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-160#orthology", "database": "AGR" }, { "id": "MGI:2444885", "url": "https://alliancegenome.org/gene/MGI:2444885#orthology", "database": "AGR" }, { "id": "RGD:1564668", "url": "https://alliancegenome.org/gene/RGD:1564668#orthology", "database": "AGR" }, { "id": "FB:FBgn0031016", "url": "https://alliancegenome.org/gene/FB:FBgn0031016#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VWI6", "url": "https://www.uniprot.org/uniprotkb/Q9VWI6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of BMP signaling pathway", "id": "GO:0030514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030514", "evidence": [ { "database": "UniProtKB", "id": "Q9VWI6", "url": "https://www.uniprot.org/uniprotkb/Q9VWI6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 108, "end_pos": 110, "annotation": 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"MSNVWGKLVLKFFKYAPSYVVCLCFLPCGMIFGYTICAFVAERNLNAGLIHYGPLILGACWALITALAMLTVKFVKKCIVYWQPWLLLAAGVFNLIGSCFYFADGFDHVGAYISYLAHSMTFVAGYSFLLTISSKGSRSLFLSGSCSCYLLGVASAVSLIVASYSRNVKELAGQTVTTEQLIDGIYVNFAGTYLSVAAAVLAILVGQKVLHFLGTVDLVNSMDNDLRIANSNGSIFEQRSEVIKRLQFFYVTKNQQWNIMLLLLFTEAVQFALFVYFVYWFALNPAIRLTEFSGIDGMFWVIFAGSLLALICQWFLSVKVTFVGSQVALISFTLLAMILCSVTDSRWSLWLLLVLFGLSYSQQQILLLEVTHLRFTECIICISYVLKLICTSIVYFYFVADAKNSYFYATDSSTLMAQGFVFLIITSLLALVVGMKVPRTHRAQLLEIQYEVYGIIFMKHQIEQLNVRWLNDGTIPTINQ", "length": 480, "header": "tr|Q9VWJ8-1|Q9VWJ8_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG7992 PE=4 SV=1 CANONICAL=Q9VWJ8-1" }, "isoforms": [ { "isoform_ac": "Q9VWJ8-1", "url": "https://www.uniprot.org/uniprotkb/Q9VWJ8/entry#Q9VWJ8-1", "sequence": { "sequence": "MSNVWGKLVLKFFKYAPSYVVCLCFLPCGMIFGYTICAFVAERNLNAGLIHYGPLILGACWALITALAMLTVKFVKKCIVYWQPWLLLAAGVFNLIGSCFYFADGFDHVGAYISYLAHSMTFVAGYSFLLTISSKGSRSLFLSGSCSCYLLGVASAVSLIVASYSRNVKELAGQTVTTEQLIDGIYVNFAGTYLSVAAAVLAILVGQKVLHFLGTVDLVNSMDNDLRIANSNGSIFEQRSEVIKRLQFFYVTKNQQWNIMLLLLFTEAVQFALFVYFVYWFALNPAIRLTEFSGIDGMFWVIFAGSLLALICQWFLSVKVTFVGSQVALISFTLLAMILCSVTDSRWSLWLLLVLFGLSYSQQQILLLEVTHLRFTECIICISYVLKLICTSIVYFYFVADAKNSYFYATDSSTLMAQGFVFLIITSLLALVVGMKVPRTHRAQLLEIQYEVYGIIFMKHQIEQLNVRWLNDGTIPTINQ", "length": 480, "header": "tr|Q9VWJ8-1|Q9VWJ8_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG7992 PE=4 SV=1 CANONICAL=Q9VWJ8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VWJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VWJ8" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VWJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VWJ8" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VWJ8" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VWJ8" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VWJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VWJ8" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VWJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VWJ8" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VWJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VWJ8" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VWJ8" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VWJ8" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"Protein" ] }, { "id": "Q9VWK2-1", "url": "https://www.uniprot.org/uniprotkb/Q9VWK2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFKLTMLMGLALILAPSTIQAKSLCRSSGYFALVDNTPDFYACQSTAYGGYSLRFLRCPAGLVFSSSMAQCVQSIAAFEARDDSNIENPTIPPSNLDESTTEKPATEAPGTTEKVTTAAPGTTEKVTTEAPGTTEKITTEAPGTTEKITTEAPGTTEKITTEAPGTTEKITTEAPGTTEKPATDAPGTTEKPATDAPGTTEKSETTDAPGTTDKSDTDAPITDEPSTAETSTDEPNTETTESGEETTIEDNVCATTGLFPTGSCTHFIVCSYAEGDELKAYTKKCPGEMQFDPFNSVCSASYDCTAGN", "length": 308, "header": "tr|Q9VWK2-1|Q9VWK2_DROME Isoform 1 of Mucin 18B, isoform A OS=Drosophila melanogaster OX=7227 GN=Muc18B PE=4 SV=1 CANONICAL=Q9VWK2-1" }, "isoforms": [ { "isoform_ac": "Q9VWK2-1", "url": "https://www.uniprot.org/uniprotkb/Q9VWK2/entry#Q9VWK2-1", "sequence": { "sequence": 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Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VWK2", "url": "https://www.uniprot.org/uniprotkb/Q9VWK2" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VWK2", "url": "https://www.uniprot.org/uniprotkb/Q9VWK2" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWK2", "url": "https://www.uniprot.org/uniprotkb/Q9VWK2" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWK2", "url": "https://www.uniprot.org/uniprotkb/Q9VWK2" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VWK2", "url": "https://www.uniprot.org/uniprotkb/Q9VWK2" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VWK2", "url": "https://www.uniprot.org/uniprotkb/Q9VWK2" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VWK2", "url": "https://www.uniprot.org/uniprotkb/Q9VWK2" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWK2", "url": "https://www.uniprot.org/uniprotkb/Q9VWK2" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWK2", "url": "https://www.uniprot.org/uniprotkb/Q9VWK2" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Obp18a", "url": "https://www.uniprot.org/uniprotkb/Q9VWM0", "locus": { "chromosome": "X", "start_pos": 19135081, "end_pos": 19135868, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0030985", "url": "https://www.ensemblgenomes.org/id/FBgn0030985" } ] } } ], "crossref": [ { "id": "FB:FBgn0030985", "url": "https://alliancegenome.org/gene/FB:FBgn0030985", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0030985", "url": "https://bgee.org/?page=gene&gene_id=FBgn0030985", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0030985", "url": "https://flybase.org/reports/FBgn0030985", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "32897", "url": "https://www.ncbi.nlm.nih.gov/gene/32897", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": 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"Protein" ] }, { "id": "Q9VWM0", "url": "https://www.uniprot.org/uniprotkb/Q9VWM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VWM0-1", "url": "https://www.uniprot.org/uniprotkb/Q9VWM0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKVVCSIAVLWICLITMWQSAGRVNAEGCLKHHNLTSAQVQAVAPSTPVADVPVAVKCYSRCLIQDYFGDDGKIDLQKVGKRGSQEDHVILSQCKQQFDGVTNLDTCDYPYLILQCYFKGKQSGTIAS", "length": 128, "header": "tr|Q9VWM0-1|Q9VWM0_DROME Isoform 1 of Odorant-binding protein 18a OS=Drosophila melanogaster OX=7227 GN=Obp18a PE=4 SV=2 CANONICAL=Q9VWM0-1" }, "isoforms": [ { "isoform_ac": "Q9VWM0-1", "url": "https://www.uniprot.org/uniprotkb/Q9VWM0/entry#Q9VWM0-1", "sequence": { "sequence": "MKVVCSIAVLWICLITMWQSAGRVNAEGCLKHHNLTSAQVQAVAPSTPVADVPVAVKCYSRCLIQDYFGDDGKIDLQKVGKRGSQEDHVILSQCKQQFDGVTNLDTCDYPYLILQCYFKGKQSGTIAS", "length": 128, "header": "tr|Q9VWM0-1|Q9VWM0_DROME Isoform 1 of Odorant-binding protein 18a OS=Drosophila melanogaster OX=7227 GN=Obp18a PE=4 SV=2 CANONICAL=Q9VWM0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VWM0", "url": "https://www.uniprot.org/uniprotkb/Q9VWM0" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VWM0", "url": "https://www.uniprot.org/uniprotkb/Q9VWM0" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWM0", "url": "https://www.uniprot.org/uniprotkb/Q9VWM0" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWM0", "url": "https://www.uniprot.org/uniprotkb/Q9VWM0" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VWM0", "url": 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Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VWM0", "url": "https://www.uniprot.org/uniprotkb/Q9VWM0" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VWM0", "url": "https://www.uniprot.org/uniprotkb/Q9VWM0" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWM0", "url": "https://www.uniprot.org/uniprotkb/Q9VWM0" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWM0", "url": "https://www.uniprot.org/uniprotkb/Q9VWM0" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, 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WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VWU7", "url": "https://www.uniprot.org/uniprotkb/Q9VWU7" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VWU7", "url": "https://www.uniprot.org/uniprotkb/Q9VWU7" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWU7", "url": "https://www.uniprot.org/uniprotkb/Q9VWU7" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWU7", "url": "https://www.uniprot.org/uniprotkb/Q9VWU7" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VWU7", "url": "https://www.uniprot.org/uniprotkb/Q9VWU7" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": 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Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VWU7", "url": "https://www.uniprot.org/uniprotkb/Q9VWU7" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VWU7", "url": "https://www.uniprot.org/uniprotkb/Q9VWU7" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi 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"2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VWV6", "url": "https://www.uniprot.org/uniprotkb/Q9VWV6" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VWV6", "url": "https://www.uniprot.org/uniprotkb/Q9VWV6" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWV6", "url": "https://www.uniprot.org/uniprotkb/Q9VWV6" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWV6", "url": "https://www.uniprot.org/uniprotkb/Q9VWV6" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VWV6", "url": "https://www.uniprot.org/uniprotkb/Q9VWV6" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VWV6", "url": "https://www.uniprot.org/uniprotkb/Q9VWV6" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VWV6", "url": "https://www.uniprot.org/uniprotkb/Q9VWV6" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWV6", "url": "https://www.uniprot.org/uniprotkb/Q9VWV6" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWV6", "url": "https://www.uniprot.org/uniprotkb/Q9VWV6" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VWV6", "url": "https://www.uniprot.org/uniprotkb/Q9VWV6" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VWV6", "url": "https://www.uniprot.org/uniprotkb/Q9VWV6" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG6186", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG6186", "resource": "KEGG Pathway" }, { "id": "R-DME-114608", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-114608", "resource": "Reactome", "description": "Platelet degranulation" }, { "id": "R-DME-381426", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-381426", "resource": "Reactome", "description": "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" }, { "id": "R-DME-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-DME-6799990", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6799990", "resource": "Reactome", "description": "Metal sequestration by antimicrobial proteins" }, { "id": "R-DME-8957275", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8957275", "resource": "Reactome", "description": "Post-translational protein phosphorylation" }, { "id": "R-DME-917937", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-917937", "resource": "Reactome", "description": "Iron uptake and transport" }, { "id": "R-DME-917977", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-917977", "resource": "Reactome", "description": "Transferrin endocytosis and recycling" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LXQ3-1", "protein_name": "Inhibitor of carbonic anhydrase", "gene_name": "Inhca", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLCMRRFRLGGTHGSWPGPAGCRTDQQKSRTCRSGARGPAANSPHCAGQCTRKYSKKLIAACIWKNDKAEVTQPCGPGCSWENKKFCICARAVPEPGLTQLGQHYCSPVNTVSLPGSHIRNRLCLAVPEKTIRWCIVSDHEATKCSSFRDNMKKVLPAGGPAVACVRKTSHLECIRDISANKIDAVTVDGALVAEADLPHHSLKPIMAEYYGSKDDPQTHYYVVAVVKKGTGFQLNQLQGKKSCHASLGWSAGWYVPLSVLLPSGSRETAAATFFSSSCVPCADGKMFPRLCQLCSGKGTDKCSCSSGEPYFGYWGALKCLQDGTGDVSFVRHLTVFEVMPRKADRDQYELLCPDNTRRPVDEYEQCYLARVPSHVVVARSVDGKEDSIQELLRVAQEHFGKDKSSTFQLFGSPHGKDLLFTDAACGLLRVPPKMDIGLYLGYELLSAIRNLKRGSEDSRRVKWCAVGQQERAKCDHWSAVSGGALACATEETPEDCIAAVMKGEADAVNLDGGFAYIAGHCGLVPGLGENYLSPHSSERLGSKCVNAALEGYYVVAVVKKSDVGITWNSLQGKKSCHTAVGTSAGWNVPMSLIYNQTGSCKFDEFFSGGCAPGANPDSRLCALCAGGNEPAHMCAANNDEGYHGSSGALRCLVEKGDVAFMKHPTVLQNTDGKNPESWAKGLKHEDFELLCLDGTRKPVTEAQNCHLDRVPNHAVFSRKDKVDFVQRMLFNQQELFGRNGFEYRMFQMFESSHKDLLFSDDTECLSNLQNKATYKTYLGPQYLTLMDNFRQCLSSELLDACTFHKH", "length": 808 }, "evidence": [ { "id": "MGI:1919025", "url": "https://alliancegenome.org/gene/MGI:1919025#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { 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"https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040709-1#orthology", "database": "AGR" }, { "id": "MGI:1919025", "url": "https://alliancegenome.org/gene/MGI:1919025#orthology", "database": "AGR" }, { "id": "MGI:98821", "url": "https://alliancegenome.org/gene/MGI:98821#orthology", "database": "AGR" }, { "id": "MGI:96837", "url": "https://alliancegenome.org/gene/MGI:96837#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "D3ZAB1-1", "protein_name": "Lactotransferrin", "gene_name": "Ltf", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRPFITVLMFLGVLGPFLARIDTVVRWCTISRNEAQKCFMWQEMLNKAGVPKLRCARKYFMPHCIQEIMMRRADAMTLSGSAIFDFYFPYKLQPIAAEVYGTKEKPRIHYYAVAVVKNSSDIRLNQLQGLKSCHAGFDTSAGWIAPLGALRPYLNWDEKSVSLEEAVSKFFSQSCVPGISKSRFPRLCSLCAGKGEHICDFSPQEPYAGYAGAFRCLRDNAGDVAFIRESTIFEELPNEAEWDQYKLLCPDNTWKPVTEYKECHLAQIPSRAVVAHVRSEKDSAIWELLHLSQEMFGKNKTSKFELFGSYLGQKDLLFKDSVIGFVRVPFTVNVWLYLTFSYIMALKSLKESKENVMALRARITWCAVGSEEKLKCDQWSRVSVGKITCISCTTTEQCIFSITMGDADAMNLDGGYIYSAGKCGLVPVLAEIQKSPNSNGSDCVDRPAEGYLAVAAVRKEDTGFTWSTVRGKKSCHTAVDRTAGWNIPMGLLVNQTNSCQFKEFFNKSCAPGSFLYSNLCALCIGDENGKDKCNPNSQERYQGYVGAFRCLAEKAGNVAFLKDATVLQNTDGKNADKWAKNLKLDDFELLCLDDTRKPVTEAKNCHLAVAPNHAVVARKDKARLVQQELLYQQVQFGRNGCRCPEEFCLFRSETKNLLFNDNTECLAKLPSKITWEEYLGKEYVVAIAHLRQCSNITQEAYNFLALRNS", "length": 709 }, "evidence": [ { "id": "MGI:96837", "url": "https://alliancegenome.org/gene/MGI:96837#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P02787-1", "protein_name": "Serotransferrin", "gene_name": "TF", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRLAVGALLVCAVLGLCLAVPDKTVRWCAVSEHEATKCQSFRDHMKSVIPSDGPSVACVKKASYLDCIRAIAANEADAVTLDAGLVYDAYLAPNNLKPVVAEFYGSKEDPQTFYYAVAVVKKDSGFQMNQLRGKKSCHTGLGRSAGWNIPIGLLYCDLPEPRKPLEKAVANFFSGSCAPCADGTDFPQLCQLCPGCGCSTLNQYFGYSGAFKCLKDGAGDVAFVKHSTIFENLANKADRDQYELLCLDNTRKPVDEYKDCHLAQVPSHTVVARSMGGKEDLIWELLNQAQEHFGKDKSKEFQLFSSPHGKDLLFKDSAHGFLKVPPRMDAKMYLGYEYVTAIRNLREGTCPEAPTDECKPVKWCALSHHERLKCDEWSVNSVGKIECVSAETTEDCIAKIMNGEADAMSLDGGFVYIAGKCGLVPVLAENYNKSDNCEDTPEAGYFAIAVVKKSASDLTWDNLKGKKSCHTAVGRTAGWNIPMGLLYNKINHCRFDEFFSEGCAPGSKKDSSLCKLCMGSGLNLCEPNNKEGYYGYTGAFRCLVEKGDVAFVKHQTVPQNTGGKNPDPWAKNLNEKDYELLCLDGTRKPVEEYANCHLARAPNHAVVTRKDKEACVHKILRQQQHLFGSNVTDCSGNFCLFRSETKDLLFRDDTVCLAKLHDRNTYEKYLGEEYVKAVGNLRKCSTSSLLEACTFRRP", "length": 698 }, "evidence": [ { "id": "MGI:98821", "url": "https://alliancegenome.org/gene/MGI:98821#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P02788-1", "protein_name": "Lactotransferrin", "gene_name": "LTF", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKLVFLVLLFLGALGLCLAGRRRSVQWCAVSQPEATKCFQWQRNMRKVRGPPVSCIKRDSPIQCIQAIAENRADAVTLDGGFIYEAGLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGGSFQLNELQGLKSCHTGLRRTAGWNVPIGTLRPFLNWTGPPEPIEAAVARFFSASCVPGADKGQFPNLCRLCAGTGENKCAFSSQEPYFSYSGAFKCLRDGAGDVAFIRESTVFEDLSDEAERDEYELLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKEDAIWNLLRQAQEKFGKDKSPKFQLFGSPSGQKDLLFKDSAIGFSRVPPRIDSGLYLGSGYFTAIQNLRKSEEEVAARRARVVWCAVGEQELRKCNQWSGLSEGSVTCSSASTTEDCIALVLKGEADAMSLDGGYVYTAGKCGLVPVLAENYKSQQSSDPDPNCVDRPVEGYLAVAVVRRSDTSLTWNSVKGKKSCHTAVDRTAGWNIPMGLLFNQTGSCKFDEYFSQSCAPGSDPRSNLCALCIGDEQGENKCVPNSNERYYGYTGAFRCLAENAGDVAFVKDVTVLQNTDGNNNEAWAKDLKLADFALLCLDGKRKPVTEARSCHLAMAPNHAVVSRMDKVERLKQVLLHQQAKFGRNGSDCPDKFCLFQSETKNLLFNDNTECLARLHGKTTYEKYLGPQYVAGITNLKKCSTSPLLEACEFLRK", "length": 710 }, "evidence": [ { "id": "MGI:96837", "url": "https://alliancegenome.org/gene/MGI:96837#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P08071-1", "protein_name": "Lactotransferrin", "gene_name": "Ltf", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRLLIPSLIFLEALGLCLAKATTVQWCAVSNSEEEKCLRWQNEMRKVGGPPLSCVKKSSTRQCIQAIVTNRADAMTLDGGTMFDAGKPPYKLRPVAAEVYGTKEQPRTHYYAVAVVKNSSNFHLNQLQGLRSCHTGIGRSAGWKIPIGTLRPYLNWNGPPASLEEAVSKFFSKSCVPGAQKDRFPNLCSSCAGTGANKCASSPEEPYSGYAGALRCLRDNAGDVAFTRGSTVFEELPNKAERDQYKLLCPDNTWKPVTEYKECHLAQVPSHAVVSRSTNDKEEAIWELLRQSQEKFGKKQASGFQLFASPSGQKDLLFKESAIGFVRVPQKVDVGLYLTFSYTTSIQNLNKKQQDVIASKARVTWCAVGSEEKRKCDQWNRASRGRVTCISFPTTEDCIVAIMKGDADAMSLDGGYIYTAGKCGLVPVLAENQKSSKSNGLDCVNRPVEGYLAVAAVRREDAGFTWSSLRGKKSCHTAVDRTAGWNIPMGLLANQTRSCKFNEFFSQSCAPGADPKSNLCALCIGDEKGENKCAPNSKERYQGYTGALRCLAEKAGNVAFLKDSTVLQNTDGKNTEEWARNLKLKDFELLCLDDTRKPVTEAKNCHLAIAPNHAVVSRTDKVEVLQQVLLDQQVQFGRNGQRCPGEFCLFQSKTKNLLFNDNTECLAKIPGKTTSEKYLGKEYVIATERLKQCSSSPLLEACAFLTQ", "length": 707 }, "evidence": [ { "id": "MGI:96837", "url": "https://alliancegenome.org/gene/MGI:96837#orthology", "database": "AGR" }, { "id": "FB:FBgn0022355", "url": "https://alliancegenome.org/gene/FB:FBgn0022355#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P12346-1", "protein_name": "Serotransferrin", "gene_name": "Tf", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRFAVGALLACAALGLCLAVPDKTVKWCAVSEHENTKCISFRDHMKTVLPADGPRLACVKKTSYQDCIKAISGGEADAITLDGGWVYDAGLTPNNLKPVAAEFYGSLEHPQTHYLAVAVVKKGTDFQLNQLQGKKSCHTGLGRSAGWIIPIGLLFCNLPEPRKPLEKAVASFFSGSCVPCADPVAFPQLCQLCPGCGCSPTQPFFGYVGAFKCLRDGGGDVAFVKHTTIFEVLPQKADRDQYELLCLDNTRKPVDQYEDCYLARIPSHAVVARNGDGKEDLIWEILKVAQEHFGKGKSKDFQLFGSPLGKDLLFKDSAFGLLRVPPRMDYRLYLGHSYVTAIRNQREGVCPEGSIDSAPVKWCALSHQERAKCDEWSVSSNGQIECESAESTEDCIDKIVNGEADAMSLDGGHAYIAGQCGLVPVMAENYDISSCTNPQSDVFPKGYYAVAVVKASDSSINWNNLKGKKSCHTGVDRTAGWNIPMGLLFSRINHCKFDEFFSQGCAPGYKKNSTLCDLCIGPAKCAPNNREGYNGYTGAFQCLVEKGDVAFVKHQTVLENTNGKNTAAWAKDLKQEDFQLLCPDGTKKPVTEFATCHLAQAPNHVVVSRKEKAARVSTVLTAQKDLFWKGDKDCTGNFCLFRSSTKDLLFRDDTKCLTKLPEGTTYEEYLGAEYLQAVGNIRKCSTSRLLEACTFHKS", "length": 698 }, "evidence": [ { "id": "MGI:98821", "url": "https://alliancegenome.org/gene/MGI:98821#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q0VIL3-1", "protein_name": "Otolith matrix protein 1", "gene_name": "otomp", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDLPGGHLAVVLFLFVLVSMSTENNIIRWCTVSDAEDQKCLDLAGNATARNLRGQLVCVRGQSPTDCMKQIKNGTADASTMYADEIYTAGFCYGLDVAVGESYNGVDGINYYVVALARTSSSDLSLLEMHERSSCHPGMRTTVGWTVPIGFLVNTSQISVDVQCNFPHAVGDFFGYSCVPGVKDPEHDPKGNNPRNLCEACIGDENDRHICANNPRERHFGEAGALRCVAENLGDVAFVKHTTVFDNMQGKNQESWALDLELEDLKLLCPDGSEANLFQHESCHLAVVPTNAVVVRLEDKCRVYKFLERVQNAFGNTTEGFSLFSSVNYGQPDVLFSDSTKKLLRVMGTYTSWLGPSYTTILRAFECEGLC", "length": 371 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-040709-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040709-1#orthology", "database": "AGR" }, { "id": "FB:FBgn0022355", "url": "https://alliancegenome.org/gene/FB:FBgn0022355#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q921I1-1", "protein_name": "Serotransferrin", "gene_name": "Tf", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRLTVGALLACAALGLCLAVPDKTVKWCAVSEHENTKCISFRDHMKTVLPPDGPRLACVKKTSYPDCIKAISASEADAMTLDGGWVYDAGLTPNNLKPVAAEFYGSVEHPQTYYYAVAVVKKGTDFQLNQLEGKKSCHTGLGRSAGWVIPIGLLFCKLSEPRSPLEKAVSSFFSGSCVPCADPVAFPKLCQLCPGCGCSSTQPFFGYVGAFKCLKDGGGDVAFVKHTTIFEVLPEKADRDQYELLCLDNTRKPVDQYEDCYLARIPSHAVVARKNNGKEDLIWEILKVAQEHFGKGKSKDFQLFSSPLGKDLLFKDSAFGLLRVPPRMDYRLYLGHNYVTAIRNQQEGVCPEGSIDNSPVKWCALSHLERTKCDEWSIISEGKIECESAETTEDCIEKIVNGEADAMTLDGGHAYIAGQCGLVPVMAEYYESSNCAIPSQQGIFPKGYYAVAVVKASDTSITWNNLKGKKSCHTGVDRTAGWNIPMGMLYNRINHCKFDEFFSQGCAPGYEKNSTLCDLCIGPLKCAPNNKEEYNGYTGAFRCLVEKGDVAFVKHQTVLDNTEGKNPAEWAKNLKQEDFELLCPDGTRKPVKDFASCHLAQAPNHVVVSRKEKAARVKAVLTSQETLFGGSDCTGNFCLFKSTTKDLLFRDDTKCFVKLPEGTTPEKYLGAEYMQSVGNMRKCSTSRLLEACTFHKH", "length": 697 }, "evidence": [ { "id": "MGI:98821", "url": "https://alliancegenome.org/gene/MGI:98821#orthology", "database": "AGR" }, { "id": "FB:FBgn0022355", "url": "https://alliancegenome.org/gene/FB:FBgn0022355#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9DBD0-1", "protein_name": "Inhibitor of carbonic anhydrase", "gene_name": "Inhca", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRLLICALLCLGTLGLCLALPEKTIRWCVVSDHEATKCSSFRDNMKKVLPAGGPAVTCVRKMSHPECIRDISANKVDAVTVDGALVAEADLPHHSLKPIMAEYYGSKDDPKTHYYVVAMAKKGTGFQLNQLRGKKSCHTGLGWSAGWYVPLSTLLPSGSRETAAATFFSSSCVPCADGKMFPSLCQLCAGKGTDKCACSSREPYFGSWGALKCLQDGTADVSFVKHLTVFEAMPTKADRDQYELLCMDNTRRPVEEYEQCYLARVPSHVVVARSVDGKEDSIQELLRVAQEHFGKDKSSPFQLFGSPHGEDLLFTDAAHGLLRVPRKIDISLYLGYEFLSAFRNLKRGLEDSQRVKWCAVGQQERTKCDQWSAVSGGALACATEETPEDCIAATMKGEADAMSLDGGFAYVAGHCGLVPVLAENYLSTHSSGRLGSKCVNAPLEGYYVVAVVKKSDVGITWKSLQGKKSCHTAVGTSEGWNVPMGLIYNQTGSCKFDAFFSRSCAPGSDPDSPLCALCVGGNNPAHMCAANNAEGYHGSSGALRCLVEKGDVAFMKHPTVLQNTDGKNPEPWAKGLKHEDFELLCLDGTRKPVTEAQSCHLARVPNRAVFSRKDKADFVRRILFNQQELFGRNGFEYMMFQMFESSAKDLLFSDDTECLSNLQNKTTYKTYLGPQYLTLMDNFRQCLSSELLDACTFHKY", "length": 700 }, "evidence": [ { "id": "MGI:1919025", "url": "https://alliancegenome.org/gene/MGI:1919025#orthology", "database": "AGR" }, { "id": "FB:FBgn0022355", "url": "https://alliancegenome.org/gene/FB:FBgn0022355#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VTZ5-1", "protein_name": "Transferrin 2", "gene_name": "Tsf2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MASSLVFVALVGALCFTLANAQHHYDEHKTTRMVWCTKSQAEQYKCQNLTVAIERDRALFDEVFLNLTCFMAYSADECIHHIDREKAHITTLDAGDVFTAGRYNSLIPIMQEKLEGGFADYQSVAVIKKGSLPDLNNLRDMRNKRVCFPWVGSLAGWIVPIHTLQREGGMEVVDCNNQVKTAASYFNNSCAVYSLSDKHNPIGDNSDKLCTLCTGKIPGGRCSSADPYFGYEGAFKCLLEKGDVAFLRHSTVNEMLQTTEFKNIAPDTFELLCRDGRRASINDYRQCNWGQVPADAIVTSSARSFSDRKQYQQFLKRIAELYSDGTRDDQSRQGGQSFNSRNNINDQNAYGQFDNNDPYRTQNQYDQYRSERLDSSFAEERNQQDGTNTSILYEKFRIFESKRYGKPNLLFQDSSRALTVIPEDDQSFTKYLGPAINFIYGIRECPVPAMTLCVTSENELDKCIKMRTALKAHLLKPELICKKMHSHINCMQFIEAGKADISVFDAGDVYTGGLNYDLVPFMSEVYNLGEPEYYVVAVAKEDDPDTELTYLKGKNTCHTGINTAAGWTYPMALFISNGWIRPYGCDSVRAAAEYFTKSCVPGAISNEYNTGVPYDSMCDLCHGTSYRYCRRDASEEYYGHTGAFRCLVEGGGHVAFMKHTTVMESTGGKRKEWWARNALNDDFELLCTDGTRAEIQDYKRCNLGKVKANAVVTRGGVNYNETQMNAYINLLTYAQQLYGRKEVDAFSFSMFSSPIGHYDLIFQDATRQLQVIPPNKRRYDAYLGSDFMRARRITDCYAGASQLALSVGLLLVGSLVAML", "length": 819 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-040709-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040709-1#orthology", "database": "AGR" }, { "id": "MGI:1919025", "url": "https://alliancegenome.org/gene/MGI:1919025#orthology", "database": "AGR" }, { "id": "MGI:98821", "url": "https://alliancegenome.org/gene/MGI:98821#orthology", "database": "AGR" }, { "id": "MGI:96837", "url": "https://alliancegenome.org/gene/MGI:96837#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "olfactory behavior", "id": "GO:0042048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042048", "evidence": [ { "database": "UniProtKB", "id": "Q9VWV6", "url": "https://www.uniprot.org/uniprotkb/Q9VWV6" } ], "pmid": "" }, { "name": "response to fungus", "id": "GO:0009620", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009620", "evidence": [ { "database": "UniProtKB", "id": "Q9VWV6", "url": "https://www.uniprot.org/uniprotkb/Q9VWV6" } ], "pmid": "" }, { "name": "iron ion transport", "id": "GO:0006826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006826", "evidence": [ { "database": "UniProtKB", "id": "Q9VWV6", "url": "https://www.uniprot.org/uniprotkb/Q9VWV6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "Q9VWV6", "url": "https://www.uniprot.org/uniprotkb/Q9VWV6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q9VWV6", "url": "https://www.uniprot.org/uniprotkb/Q9VWV6" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VWV6", "url": "https://www.uniprot.org/uniprotkb/Q9VWV6" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "Q9VWV6", "url": "https://www.uniprot.org/uniprotkb/Q9VWV6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VWV6", "url": "https://www.uniprot.org/uniprotkb/Q9VWV6" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "Q9VWV6", "url": "https://www.uniprot.org/uniprotkb/Q9VWV6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VWV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWV6" }, { "id": "PS51408", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51408" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Transferrin-like", "eco_id": "ECO_0000259", "start_pos": 34, "end_pos": 378, "start_aa": "Tyr", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VWW1-1", "uniprot_ac": "Q9VWW1", "uniprot_id": "Q9VWW1_DROME", "mass": { "chemical_mass": 52852.0, "monoisotopic_mass": 52852.0 }, "refseq": { "ac": "NP_001285403", "name": "uncharacterized protein, isoform B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285403" }, "gene_names": [ { "name": "Dmel\\CG6106", "type": "recommended", "evidence": [ { "id": "Q9VWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWW1" } ] }, { "name": "CG6106", "type": "synonym", "evidence": [ { "id": "NP_001285403", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285403" }, { "id": "Q9VWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWW1" } ] }, { "name": "Dmel\\CG6106", "type": "synonym", "evidence": [ { "id": "NP_001285403", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285403" } ] }, { "name": "Dmel_CG6106", "type": "synonym", "evidence": [ { "id": "Q9VWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWW1" } ] } ], "protein_names": [ { "name": "allantoinase", "type": "recommended", "evidence": [ { "id": "Q9VWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWW1/entry#names_and_taxonomy" } ] }, { "name": "3.5.2.5", "type": "synonym", "evidence": [ { "id": "Q9VWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWW1/entry#names_and_taxonomy" } ] }, { "name": "CG6106-PB", "type": "synonym", "evidence": [ { "id": "NP_001285403", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285403" } ] }, { "name": "uncharacterized protein, isoform B", "type": "synonym", "evidence": [ { "id": "NP_001285403", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285403" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VWW1", "url": "https://www.uniprot.org/uniprotkb/Q9VWW1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG6106", "url": "https://www.uniprot.org/uniprotkb/Q9VWW1", "locus": { "chromosome": "X", "start_pos": 18362527, "end_pos": 18358881, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0030914", "url": "https://www.ensemblgenomes.org/id/FBgn0030914" } ] } } ], "crossref": [ { "id": "FB:FBgn0030914", "url": "https://alliancegenome.org/gene/FB:FBgn0030914", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0030914", "url": "https://bgee.org/?page=gene&gene_id=FBgn0030914", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01315", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01315", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0030914", "url": "https://flybase.org/reports/FBgn0030914", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "32816", "url": "https://www.ncbi.nlm.nih.gov/gene/32816", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011059", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011059", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024403", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024403", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032466", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032466", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050138", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050138", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG6106", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG6106", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SRLHVCH", "url": "https://omabrowser.org/oma/group/SRLHVCH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VWW1", "url": "https://www.orthodb.org/?gene=Q9VWW1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43668", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43668", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43668:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43668:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01979", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01979", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12890", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12890", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001285403", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285403", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VWW1", "url": "https://www.uniprot.org/uniprotkb/Q9VWW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VWW1-1", "url": "https://www.uniprot.org/uniprotkb/Q9VWW1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDLLFLSRRIFLGDGSQNALIHGGIIVDTEGIIRRVLRSPQEVNTYLYNTESESVYDFGDLVLMPGLIDPNVHINEPGRKDWEGFATATKAAAAGGFTTIIDRPTNAQPPTVSVAHLKAKTSTARGKIYVDVGFWGGLVPGNGDQLAALLGAGVMGLQCTLCDPAAPVSQEFPAVNESQLEEALSQLDKDQAEGEAIVAVHAELPLTTEIHPDEEAPREYGTFLVTRPPQMEISATQLLCRLANRHPRRCIHILNCSSGESLPLVEECRRQGGNLTVDTCPHYLALAAEDVPDCGTEFKTWPPIRERRNQEQLWQALRPGGAIRMIGSDHSPATPGARALTCGRGRGNFLKAWPGINSLQLSLSVVWTAAANRRGSANLTIADIHRLMCQEPANLCGLSASKGRIAEGYDADFCVWSPEEEFTVGPELLYTATKATPYAGQKLRGVVHATVVRGLHVYQQFEGFGQPLGKVLLRRSSRKLVKFVSM", "length": 486, "header": "tr|Q9VWW1-1|Q9VWW1_DROME Isoform 1 of allantoinase OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG6106 PE=3 SV=2 CANONICAL=Q9VWW1-1" }, "isoforms": [ { "isoform_ac": "Q9VWW1-1", "url": "https://www.uniprot.org/uniprotkb/Q9VWW1/entry#Q9VWW1-1", "sequence": { "sequence": "MDLLFLSRRIFLGDGSQNALIHGGIIVDTEGIIRRVLRSPQEVNTYLYNTESESVYDFGDLVLMPGLIDPNVHINEPGRKDWEGFATATKAAAAGGFTTIIDRPTNAQPPTVSVAHLKAKTSTARGKIYVDVGFWGGLVPGNGDQLAALLGAGVMGLQCTLCDPAAPVSQEFPAVNESQLEEALSQLDKDQAEGEAIVAVHAELPLTTEIHPDEEAPREYGTFLVTRPPQMEISATQLLCRLANRHPRRCIHILNCSSGESLPLVEECRRQGGNLTVDTCPHYLALAAEDVPDCGTEFKTWPPIRERRNQEQLWQALRPGGAIRMIGSDHSPATPGARALTCGRGRGNFLKAWPGINSLQLSLSVVWTAAANRRGSANLTIADIHRLMCQEPANLCGLSASKGRIAEGYDADFCVWSPEEEFTVGPELLYTATKATPYAGQKLRGVVHATVVRGLHVYQQFEGFGQPLGKVLLRRSSRKLVKFVSM", "length": 486, "header": "tr|Q9VWW1-1|Q9VWW1_DROME Isoform 1 of allantoinase OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG6106 PE=3 SV=2 CANONICAL=Q9VWW1-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 334, "start_aa": "Thr", "end_pos": 334, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr334", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VWW1", "url": "https://www.uniprot.org/uniprotkb/Q9VWW1" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VWW1", "url": "https://www.uniprot.org/uniprotkb/Q9VWW1" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWW1", "url": "https://www.uniprot.org/uniprotkb/Q9VWW1" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWW1", "url": "https://www.uniprot.org/uniprotkb/Q9VWW1" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VWW1", "url": "https://www.uniprot.org/uniprotkb/Q9VWW1" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VWW1", "url": "https://www.uniprot.org/uniprotkb/Q9VWW1" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VWW1", "url": "https://www.uniprot.org/uniprotkb/Q9VWW1" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWW1", "url": "https://www.uniprot.org/uniprotkb/Q9VWW1" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWW1", "url": "https://www.uniprot.org/uniprotkb/Q9VWW1" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VWW1", "url": "https://www.uniprot.org/uniprotkb/Q9VWW1" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VWW1", "url": "https://www.uniprot.org/uniprotkb/Q9VWW1" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG6106", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG6106", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AB13ABT0-1", "protein_name": "allantoinase", "gene_name": "", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEPGSAVSAVRSQRVLCGEKILPAVIVIKEGKIHSVLPDSEASAHVAGKVLDVGDSLIMPGIVDSHVHVNEPGRTDWEGYWTATRAAAAGGITTIADMPLNTIPPTTTLRNFNEKLCAATGQCFVDTAFWGGVIPGNQMELKPMCQAGVAGFKCFLIHSGVEEFPHVTDADLHAAMKQLQGTNSVLLFHAEQELSHPVAEKGDPQEYSTFLKSRPDIMELEAIHTVIEFCLQYQVRCHIVHLSSAEPLELIRAAKQAGAPLTVETTHHYLNLSAEDIPGRATQFKCCPPIRGTANQELLWSALKAGDIDMVVSDHSPCTPDLKCLDSGDFTQAWGGISSLQFVLSLFWTSASKRGFSFSDAARLLCEEPARLCRLDNQKGSLIPGHDADLVIWDPEKEFTVKEDNIHHKNKLTPYLDRVLRGMVRFTIVRGQVVYSHGSFSSQPLGKHLLIQNKSTTTV", "length": 459 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-041212-22", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041212-22#orthology", "database": "AGR" }, { "id": "FB:FBgn0030914", "url": "https://alliancegenome.org/gene/FB:FBgn0030914#orthology", "database": "AGR" }, { "id": "SGD:S000001466", "url": "https://alliancegenome.org/gene/SGD:S000001466#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O08553-1", "protein_name": "Dihydropyrimidinase-related protein 2", "gene_name": "Dpysl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYQGKKNIPRITSDRLLIKGGKIVNDDQSFYADIYMEDGLIKQIGENLIVPGGVKTIEAHSRMVIPGGIDVHTRFQMPDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAFDQWREWADSKSCCDYSLHVDITEWHKGIQEEMEALVKDHGVNSFLVYMAFKDRFQLTDSQIYEVLSVIRDIGAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRSITIANQTNCPLYVTKVMSKSAAEVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEERMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRISVGSDADLVIWDPDSVKTISAKTHNSALEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYKRIKARSRLAELRGVPRGLYDGPVCEVSVTPKTVTPASSAKTSPAKQQAPPVRNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANITSLG", "length": 572 }, "evidence": [ { "id": "SGD:S000001466", "url": "https://alliancegenome.org/gene/SGD:S000001466#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O14531-1", "protein_name": "Dihydropyrimidinase-related protein 4", "gene_name": "DPYSL4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSFQGKKSIPRITSDRLLIRGGRIVNDDQSFYADVHVEDGLIKQIGENLIVPGGIKTIDAHGLMVLPGGVDVHTRLQMPVLGMTPADDFCQGTKAALAGGTTMILDHVFPDTGVSLLAAYEQWRERADSAACCDYSLHVDITRWHESIKEELEALVKEKGVNSFLVFMAYKDRCQCSDSQMYEIFSIIRDLGALAQVHAENGDIVEEEQKRLLELGITGPEGHVLSHPEEVEAEAVYRAVTIAKQANCPLYVTKVMSKGAADAIAQAKRRGVVVFGEPITASLGTDGSHYWSKNWAKAAAFVTSPPVNPDPTTADHLTCLLSSGDLQVTGSAHCTFTTAQKAVGKDNFALIPEGTNGIEERMSMVWEKCVASGKMDENEFVAVTSTNAAKIFNFYPRKGRVAVGSDADLVIWNPKATKIISAKTHNLNVEYNIFEGVECRGAPAVVISQGRVALEDGKMFVTPGAGRFVPRKTFPDFVYKRIKARNRLAEIHGVPRGLYDGPVHEVMVPAKPGSGAPARASCPGKISVPPVRNLHQSGFSLSGSQADDHIARRTAQKIMAPPGGRSNITSLS", "length": 572 }, "evidence": [ { "id": "SGD:S000001466", "url": "https://alliancegenome.org/gene/SGD:S000001466#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O35098-1", "protein_name": "Dihydropyrimidinase-related protein 4", "gene_name": "Dpysl4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSFQGKKSIPRITSDRLLIKGGKIVNDDQSFHADLYVEDGLIKQIGENLIVPGGIKTIDAHGLMVLPGGVDVHTRLQMPVMGMTPADDFCQGTKAALAGGTTMILDHVFPDAGVSLLAAYEQWRERADSAACCDYSLHVDIPRWHESTKEELEALVRDKGVNSFLVFMAYKDRCQCTDGQIYEIFSLIRDLGAVAQVHAENGDIVEEEQKRLLEQGITGPEGHVLSHPEEVEAEAVYRAVTIAKQANCPLYVTKVMSKGAADMVAQAKRRGVVVFGEPITASLGTDGSHYWSKNWAKAAAFVTSPPINPDPTTADHLTSLLSSGDLQVTGSAHCTFTTAQKAVGKDNFTLIPEGVNGIEERMSVVWEKCVASGKMDENEFVAVTSTNAAKIFNFYPRKGRVAVGSDADLVIWNPRATKVFSAKSHNLNVEYNIFEGVECRGVPTVVISQGRVVLEDGNLLVTPGAGRFIPRKTFPDFVYKRIKARNRLAEIHGVPRGLYDGPVHEVMLPAKPGSGTQARASCSGKISVPPVRNLHQSGFSLSGSQADDHIARRTAQKIMAPPGGRSNITSLS", "length": 572 }, "evidence": [ { "id": "SGD:S000001466", "url": "https://alliancegenome.org/gene/SGD:S000001466#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P32375-1", "protein_name": "Allantoinase", "gene_name": "DAL1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MPINAITSDHVIINGANKPATIVYSTESGTILDVLEGSVVMEKTEITKYEIHTLENVSPCTILPGLVDSHVHLNEPGRTSWEGFETGTQAAISGGVTTVVDMPLNAIPPTTNVENFRIKLEAAEGQMWCDVGFWGGLVPHNLPDLIPLVKAGVRGFKGFLLDSGVEEFPPIGKEYIEEALKVLAEEDTMMMFHAELPKAHEDQQQPEQSHREYSSFLSSRPDSFEIDAINLILECLRARNGPVPPVHIVHLASMKAIPLIRKARASGLPVTTETCFHYLCIAAEQIPDGATYFKCCPPIRSESNRQGLWDALREGVIGSVVSDHSPCTPELKNLQKGDFFDSWGGIASVGLGLPLMFTQGCSLVDIVTWCCKNTSHQVGLSHQKGTIAPGYDADLVVFDTASKHKISNSSVYFKNKLTAYNGMTVKGTVLKTILRGQVVYTNANGVSKTPLGQTLLDSRR", "length": 460 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-041212-22", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041212-22#orthology", "database": "AGR" }, { "id": "FB:FBgn0030914", "url": "https://alliancegenome.org/gene/FB:FBgn0030914#orthology", "database": "AGR" }, { "id": "SGD:S000001466", "url": "https://alliancegenome.org/gene/SGD:S000001466#orthology", "database": "AGR" }, { "id": "Q9VWW1", "url": "https://omabrowser.org/oma/group/Q9VWW1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P47942-1", "protein_name": "Dihydropyrimidinase-related protein 2", "gene_name": "Dpysl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSYQGKKNIPRITSDRLLIKGGKIVNDDQSFYADIYMEDGLIKQIGENLIVPGGVKTIEAHSRMVIPGGIDVHTRFQMPDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAFDQWREWADSKSCCDYSLHVDITEWHKGIQEEMEALVKDHGVNSFLVYMAFKDRFQLTDSQIYEVLSVIRDIGAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRSITIANQTNCPLYVTKVMSKSAAEVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEERMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRISVGSDADLVIWDPDSVKTISAKTHNSALEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYKRIKARSRLAELRGVPRGLYDGPVCEVSVTPKTVTPASSAKTSPAKQQAPPVRNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANITSLG", "length": 572 }, "evidence": [ { "id": "SGD:S000001466", "url": "https://alliancegenome.org/gene/SGD:S000001466#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P97427-1", "protein_name": "Dihydropyrimidinase-related protein 1", "gene_name": "Crmp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSHQGKKSIPHITSDRLLIRGGRIINDDQSFYADVYLEDGLIKQIGENLIVPGGVKTIEANGRMVIPGGIDVNTYLQKPSQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGSSLLTSFEKWHEAADTKSCCDYSLHVDITSWYDGVREELEVLVQDKGVNSFQVYMAYKDLYQMSDSQLYEAFTFLKGLGAVILVHAENGDLIAQEQKRILEMGITGPEGHALSRPEELEAEAVFRAIAIAGRINCPVYITKVMSKSAADIIALARKKGPLVFGEPIAASLGTDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYLTSLLACGDLQVTGSGHCPYSTAQKAVGKDNFTLIPEGVNGIEERMTVVWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADVVIWDPDKMKTITAKSHKSTVEYNIFEGMECHGSPLVVISQGKIVFEDGNISVSKGMGRFIPRKPFPEHLYQRVRIRSKVFGLHSVSRGMYDGPVYEVPATPKHAAPAPSAKSSPSKHQPPPIRNLHQSNFSLSGAQIDDNNPRRTGHRIVAPPGGRSNITSLG", "length": 572 }, "evidence": [ { "id": "SGD:S000001466", "url": "https://alliancegenome.org/gene/SGD:S000001466#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q14117-1", "protein_name": "Dihydropyrimidinase", "gene_name": "DPYS", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRDRTCTPTPVERAPYKGEVATLKSRVTKEDATAGTRKQAHP", "length": 519 }, "evidence": [ { "id": "SGD:S000001466", "url": "https://alliancegenome.org/gene/SGD:S000001466#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q14194-1", "protein_name": "Dihydropyrimidinase-related protein 1", "gene_name": "CRMP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSYQGKKSIPHITSDRLLIKGGRIINDDQSLYADVYLEDGLIKQIGENLIVPGGVKTIEANGRMVIPGGIDVNTYLQKPSQGMTAADDFFQGTRAALVGGTTMIIDHVVPEPGSSLLTSFEKWHEAADTKSCCDYSLHVDITSWYDGVREELEVLVQDKGVNSFQVYMAYKDVYQMSDSQLYEAFTFLKGLGAVILVHAENGDLIAQEQKRILEMGITGPEGHALSRPEELEAEAVFRAITIAGRINCPVYITKVMSKSAADIIALARKKGPLVFGEPIAASLGTDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYLTSLLACGDLQVTGSGHCPYSTAQKAVGKDNFTLIPEGVNGIEERMTVVWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADVVIWDPDKLKTITAKSHKSAVEYNIFEGMECHGSPLVVISQGKIVFEDGNINVNKGMGRFIPRKAFPEHLYQRVKIRNKVFGLQGVSRGMYDGPVYEVPATPKYATPAPSAKSSPSKHQPPPIRNLHQSNFSLSGAQIDDNNPRRTGHRIVAPPGGRSNITSLG", "length": 572 }, "evidence": [ { "id": "SGD:S000001466", "url": "https://alliancegenome.org/gene/SGD:S000001466#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q14195-1", "protein_name": "Dihydropyrimidinase-related protein 3", "gene_name": "DPYSL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSYQGKKNIPRITSDRLLIKGGRIVNDDQSFYADIYMEDGLIKQIGDNLIVPGGVKTIEANGKMVIPGGIDVHTHFQMPYKGMTTVDDFFQGTKAALAGGTTMIIDHVVPEPESSLTEAYEKWREWADGKSCCDYALHVDITHWNDSVKQEVQNLIKDKGVNSFMVYMAYKDLYQVSNTELYEIFTCLGELGAIAQVHAENGDIIAQEQTRMLEMGITGPEGHVLSRPEELEAEAVFRAITIASQTNCPLYVTKVMSKSAADLISQARKKGNVVFGEPITASLGIDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYINSLLASGDLQLSGSAHCTFSTAQKAIGKDNFTAIPEGTNGVEERMSVIWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRISVGSDSDLVIWDPDAVKIVSAKNHQSAAEYNIFEGMELRGAPLVVICQGKIMLEDGNLHVTQGAGRFIPCSPFSDYVYKRIKARRKMADLHAVPRGMYDGPVFDLTTTPKGGTPAGSARGSPTRPNPPVRNLHQSGFSLSGTQVDEGVRSASKRIVAPPGGRSNITSLS", "length": 570 }, "evidence": [ { "id": "SGD:S000001466", "url": "https://alliancegenome.org/gene/SGD:S000001466#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q16555-1", "protein_name": "Dihydropyrimidinase-related protein 2", "gene_name": "DPYSL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSYQGKKNIPRITSDRLLIKGGKIVNDDQSFYADIYMEDGLIKQIGENLIVPGGVKTIEAHSRMVIPGGIDVHTRFQMPDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAFDQWREWADSKSCCDYSLHVDISEWHKGIQEEMEALVKDHGVNSFLVYMAFKDRFQLTDCQIYEVLSVIRDIGAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRAITIANQTNCPLYITKVMSKSSAEVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEERMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRIAVGSDADLVIWDPDSVKTISAKTHNSSLEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYKRIKARSRLAELRGVPRGLYDGPVCEVSVTPKTVTPASSAKTSPAKQQAPPVRNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANITSLG", "length": 572 }, "evidence": [ { "id": "SGD:S000001466", "url": "https://alliancegenome.org/gene/SGD:S000001466#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q55C91-1", "protein_name": "Probable allantoinase 2", "gene_name": "allB2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIWKVIFSIWFLLFQNFVLSAKNDDNKLKVIRGRNVIYNGNVIPLSILIRNGKTIGIKDYSFNPKKLNENYEILYDDRECNNNEDFIIMGGLVDSHVHVNEPGRTEWEGFESATSAAAAGGVTTIVDMPLNSSPVTTSFKNLLDKIESMKGKLRVDVGLLGGIVPGNSKEIKKMVLQGGVLGFKSFLLPSGIDEFPPVNENDIQEAMNEMKLLKCQYNNSDVIMMFHAEVEEPIKEATVRLKNENADPKLYKTYLDSRPKISENQAISKLIDITRQNQIVSTHIVHLSSSESIEQIREAMDQGVPISAETTYNYLHLTSESVPYGNTLFKSAPPVREHENKELLWNAIINGTIKLIVSDHSPCTINLKQLKEDNQSIGDFLKAWGGISSLELGLPIIWTECKNRGIPITQLSEWLSNGPSKLVGLNDRKGSIEIGRDADFVIFNPNESFIVNEKKLFLKNKFSAYNGEKLFGVVYETILRGNSIFKKGDNKIKKIIGQRLIKSNLINKK", "length": 510 }, "evidence": [ { "id": "Q9VWW1", "url": "https://omabrowser.org/oma/group/Q9VWW1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q62188-1", "protein_name": "Dihydropyrimidinase-related protein 3", "gene_name": "Dpysl3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYQGKKNIPRITSDRLLIKGGRIVNDDQSFYADIYMEDGLIKQIGDNLIVPGGVKTIEANGKMVIPGGIDVHTHFQMPYKGMTTVDDFFQGTKAALAGGTTMIIDHVVPEPESSLTEAYEKWREWADGKSCCDYALHVDITHWNDSVKQEVQSLSKEKGVNSFMVYMAYKDLYQVSNTELYEIFTCLGELGAIAQVHAENGDIIAQEQARMLEMGITGPEGHVLSRPEELEAEAVFRAITVASQTNCPLYVTKVMSKSAADLISQARKKGNVVFGEPITASLGIDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYINSLLASGDLQLSGSAHCTFSTAQKAIGKDNFTAIPEGTNGVEERMSVIWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDSDLVIWDPDALKIVSAKNHQSVAEYNIFEGMELRGAPLVVICQGKIMLEDGNLHVTQGAGRFIPCSPFSDYVYKRIKARRKMADLHAVPRGMYDGPVFDLTTTPKGGTPAGSTRGSPTRPNPPVRNLHQSGFSLSGTQVDEGVRSASKRIVAPPGGRSNITSLS", "length": 570 }, "evidence": [ { "id": "SGD:S000001466", "url": "https://alliancegenome.org/gene/SGD:S000001466#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q62950-1", "protein_name": "Dihydropyrimidinase-related protein 1", "gene_name": "Crmp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSHQGKKSIPHITSDRLLIRGGRIINDDQSFYADVYLEDGLIKQIGENLIVPGGVKTIEANGRMVIPGGIDVNTYLQKPSQGMTSADDFFQGTRAALAGGTTMIIDHVVPEPGSSLLTSFEKWHEAADTKSCCDYSLHVDITSWYDGVREELEVLVQDKGVNSFQVYMAYKDLYQMSDSQLYEAFTFLKGLGAVILVHAENGDLIAQEQKRILEMGITGPEGHALSRPEELEAEAVFRAIAIAGRINCPVYITKVMSKSAADIIALARKKGPLVFGEPIAASLGTDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYLTSLLACGDLQVTGSGHCPYSTAQKAVGKDNFTLIPEGVNGIEERMTVVWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADVVIWDPDKMKTLTAKSHKSTVEYNIFEGMECHGSPLVVISQGKIVFEDGNISVSKGMGRFIPRKPFPEHLYQRVRIRSKVFGLHSVSRGMYDGPVYEVPATPKHAAPAPSAKSSPSKHQPPPIRNLHQSNFSLSGAQIDDNNPRRTGHRIVAPPGGRSNITSLG", "length": 572 }, "evidence": [ { "id": "SGD:S000001466", "url": "https://alliancegenome.org/gene/SGD:S000001466#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q62951-1", "protein_name": "Dihydropyrimidinase-related protein 4", "gene_name": "Dpysl4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "IPRITSDRLLIKGGKIVNDDQSFHADLYVEDGLIKQIGENLIVPGGIKTIDAHGLMVLPGGVDVHTRLQMPVLGMTPADDFCQGTKAALAGGTTMILDHVFPDAGVSLLAAYEQWRERADSAACCDYSLHVDIPRWHESTKEELEALVRDKGVNSFLVFMAYKDRCQCTDGQIYEIFSLIRDLGAVAQVHAENGDIVEEEQKRLLEQGITGPEGHVLSHPEEVEAEAVYRAVTIAKQANCPLYITKVMSKGAADMVAQAKRRGVVVFGEPITASLGTDGSHYWSKNWAKAAAFVTSPPINPDPTTADHLTSLLSSGDLQVTGSAHCTFTTAQKAVGKDNFTLIPEGINGIEERMSVVWEKCVASGKMDENEFVAVTSTNAAKIFNFYPRKGRVAVGSDADLVIWNPRATKVISAKSHNLNVEYNIFEGVECRGMPTVVISQGRVVLEDGNLLVTPGAGRFIPRKTFPDFVYKRIKARNRLAEIHGVPRGLYDGPVHEVMLPAKPGSGTQARASCPGKISVPPVRNLHQSGFSLSGSQADDHIARRTAQKIMAPPGGRSNITSLS", "length": 564 }, "evidence": [ { "id": "SGD:S000001466", "url": "https://alliancegenome.org/gene/SGD:S000001466#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q62952-1", "protein_name": "Dihydropyrimidinase-related protein 3", "gene_name": "Dpysl3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSYQGKKNIPRITSDRLLIKGGRIVNDDQSFYADIYMEDGLIKQIGDNLIVPGGVKTIEANGKMVMPGGIDVHTHFQMPYKGMTTVDDFFQGTKAALAGGTTMIIDHVVPEPESSLTEAYEKWREWADGKSCCDYALHVDITHWNDSVKQEVQNLSKEKGVNSFMVYMAYKDLYQVSNTELYEIFTCLGELGAIAQVHAENGDIIAQEQARMLEMGITGPEGHVLSRPEELEAEAVFRAITVASQTNCPLYVTKVMSKSAADLISQARKKGNVVFGEPITASLGIDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYINSLLASGDLQLSGSAHCTFSTAQKAIGKDNFTAIPEGTNGVEERMSVIWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDSDLVIWDPDAVKIVSAKNHQSVAEYNIFEGMELRGAPLVVICQGKIMLEDGNLHVTQGAGRFIPCSPFSDYVYKRIKARRKMADLHAVPRGMYDGPVFDLTTTPKGGTPAGSTRGSPTRPNPPVRNLHQSGFSLSGTQVDEGVRSASKRIVAPPGGRSNITSLS", "length": 570 }, "evidence": [ { "id": "SGD:S000001466", "url": "https://alliancegenome.org/gene/SGD:S000001466#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q63150-1", "protein_name": "Dihydropyrimidinase", "gene_name": "Dpys", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPQERLLIRGGRVVNDDFSQVADVLVEDGVVRALGRDLLPPGDTSRGLRILDAAGKLVLPGGIDTHTHMQFPFMGSQSVDDFHQGTKAALAGGTTMIIDFAIPQKGSSLIEAFETWRNWADPKVCCDYSLHVAVTWWSDKVKEEMKTLAQDKGVNSFKMFMAYKDLYMVQDQQMYAAFSQCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYIVHVMSKSAAKVIADAKREGKVVYGEPIAAGLGTDGTQYWNKEWRHAAHHVMGPPLRPDPSTPGFLMNLLANGDLTTTGSDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPKKGRIAVGSDADIVIWDPEATRTISAKTHHQAVNFNIFEGMVCHGVPLVTISRGRVVYEAGVFDVTAGHGKFIPRQPFAEFIYKRVKQRDQTCTPIPVKRAPYKGEVITLKPRETKEDDTAGTRMQGHS", "length": 519 }, "evidence": [ { "id": "SGD:S000001466", "url": "https://alliancegenome.org/gene/SGD:S000001466#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q94AP0-1", "protein_name": "Allantoinase", "gene_name": "ALN", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MERTLLQWRLLPLLALIVALFSFFFASPRSLQGNNKCSLLPHDHYWISSKRIVTPNGLISGSVEVKGGIIVSVVKEVDWHKSQRSRVKVIDYGEAVLMPGLIDVHVHLDDPGRSEWEGFPSGTKAAAAGGITTLVDMPLNSFPSTVSPETLKLKIEAAKNRIHVDVGFWGGLVPDNALNSSALESLLDAGVLGLKSFMCPSGINDFPMTNITHIKEGLSVLAKYKRPLLVHAEIERDLEIEDGSENDPRSYLTYLKTRPTSWEEGAIRNLLSVTENTRIGGSAEGAHLHIVHLSDASSSLDLIKEAKGKGDSVTVETCPHYLAFSAEEIPEGDTRFKCSPPIRDAANREKLWEALMEGDIDMLSSDHSPTKPELKLMSDGNFLKAWGGISSLQFVLPITWSYGKKYGVTLEQVTSWWSDRPSKLAGLHSKGAVTVGKHADLVVWEPEAEFDVDEDHPIHFKHPSISAYLGRRLSGKVVSTFVRGNLVFGEGKHASDACGSLQLATT", "length": 506 }, "evidence": [ { "id": "Q9VWW1", "url": "https://omabrowser.org/oma/group/Q9VWW1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9BPU6-1", "protein_name": "Dihydropyrimidinase-related protein 5", "gene_name": "DPYSL5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLANSASVRILIKGGKVVNDDCTHEADVYIENGIIQQVGRELMIPGGAKVIDATGKLVIPGGIDTSTHFHQTFMNATCVDDFYHGTKAALVGGTTMIIGHVLPDKETSLVDAYEKCRGLADPKVCCDYALHVGITWWAPKVKAEMETLVREKGVNSFQMFMTYKDLYMLRDSELYQVLHACKDIGAIARVHAENGELVAEGAKEALDLGITGPEGIEISRPEELEAEATHRVITIANRTHCPIYLVNVSSISAGDVIAAAKMQGKVVLAETTTAHATLTGLHYYHQDWSHAAAYVTVPPLRLDTNTSTYLMSLLANDTLNIVASDHRPFTTKQKAMGKEDFTKIPHGVSGVQDRMSVIWERGVVGGKMDENRFVAVTSSNAAKLLNLYPRKGRIIPGADADVVVWDPEATKTISASTQVQGGDFNLYENMRCHGVPLVTISRGRVVYENGVFMCAEGTGKFCPLRSFPDTVYKKLVQREKTLKVRGVDRTPYLGDVAVVVHPGKKEMGTPLADTPTRPVTRHGGMRDLHESSFSLSGSQIDDHVPKRASARILAPPGGRSSGIW", "length": 564 }, "evidence": [ { "id": "SGD:S000001466", "url": "https://alliancegenome.org/gene/SGD:S000001466#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9EQF5-1", "protein_name": "Dihydropyrimidinase", "gene_name": "Dpys", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPQGRLLIRGGRIVNDDFSQVADVLVEDGVVRALGRDLLPPEDASRGLRILDAAGKLVLPGGIDTHTHMQFPFMGSQSVDDFYQGTKAALAGGTTMIIDFAIPQKGSSLIEAFETWRNWADPKVCCDYSLHVAVTWWSDKVKEEMKTLARDKGVNSFKMFMAYKGLYMVQDEQLYAAFSQCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYVVHVMSKSAAKVVADARRAGNVVYGEPIAAGLGTDGRQYWSEEWSHAAHHVMGPPLRPDPLTPGFLMDLLANGDLTTTGSDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPKKGRIAVGSDADIVIWDPEATRRISAKTHHQAVNFNIFEGMVCHGVPLVTISRGRVVYEAGVFNVTAGHGKFIPRQPFAEYIYKRIKQRDQTCTPVPVKRAPYKGEVTTLKARETKEDDTAGTRMQGHS", "length": 519 }, "evidence": [ { "id": "SGD:S000001466", "url": "https://alliancegenome.org/gene/SGD:S000001466#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EQF6-1", "protein_name": "Dihydropyrimidinase-related protein 5", "gene_name": "Dpysl5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLANSASVRILIKGGKVVNDDCTHEADVYIESGIIQQVGRELMIPGGAKVIDATGKLVIPGGIDTSTHFHQTFMNATCVDDFYHGTKAALVGGTTMIIGHVLPDKETSLVEAYEKCRALADPKVCCDYALHVGITWWAPKVKAEMETLVREKGVNSFQMFMTYKDLYMLRDSELYQVFHACRDIGAIPRVHAENGELVAEGAKEALDLGITGPEGIEISHPEELEAEATHRVITIANRTHCPIYLVNVSSISAGDVIAAAKMQGKVVLAETTNAHATLTGLHYYHQDWSHAAAYVTVPPLRLDTNTSTYLMSLLANDTLNIVASDHRPFTTKQKAMGKEDFTKIPHGVSGVQDRMSVVWERGVVGGKMDENRFVAVTSSNAAKILNLYPRKGRIIPGADADVVVWDPEATKTISASTQVQGGDFNLYENMRCHGVPLVTISRGRVVYENGVFMCAEGTGKFCPLRSFPDIVYKKLVQREKTLKVRGVDRTPYLGDVAIVVHPGKKEMGTPLADTPTRPVTRHGGMRDLHESSFSLSGSQIDDHVPKRASARILAPPGGRSSGIW", "length": 564 }, "evidence": [ { "id": "SGD:S000001466", "url": "https://alliancegenome.org/gene/SGD:S000001466#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JHU0-1", "protein_name": "Dihydropyrimidinase-related protein 5", "gene_name": "Dpysl5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLANSASVRILIKGGKVVNDDCTHEADVYIENGIIQQVGRELMIPGGAKVIDATGKLVIPGGIDTSTHFHQTFMNATCVDDFYHGTKAALVGGTTMIIGHVLPDKETSLVEAYEKCRALADPKVCCDYALHVGITWWAPKVKAEMETLVREKGVNSFQMFMTYKDLYMLRDSELYQVFHACRDFGAIPRVHAENGELVAEGAKEALDLGITGPEGIEISHPEELEAEATHRVITIANRTHCPIYLVNVSSISAGDVIAAAKMQGKVVLAETTNAHATLTGLHYYHQDWSHAAAYVTVPPLRLDTNTSTYLMSLLANDTLNIVASDHRPFTTKQKAMGKEDFTKIPHGVSGVQDRMSVVWERGVVGGKMDENRFVAVTSSNAAKILNLYPRKGRIIPGADADVVVWDPEATKTISASTQVQGGDFNLYENMRCHGVPLVTISRGRVVYENGVFMCAEGTGKFCPLRSFPDIVYKKLVQREKTLKVRGVDRTPYLGDVAVVVNPGKKEMGTPLADTPTRPVTRHGGMRDLHESSFSLSGSQIDDHVPKRASARILAPPGGRSSGIW", "length": 564 }, "evidence": [ { "id": "SGD:S000001466", "url": "https://alliancegenome.org/gene/SGD:S000001466#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "purine nucleobase catabolic process", "id": "GO:0006145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006145", "evidence": [ { "database": "UniProtKB", "id": "Q9VWW1", "url": "https://www.uniprot.org/uniprotkb/Q9VWW1" } ], "pmid": "" }, { "name": "allantoin catabolic process", "id": "GO:0000256", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000256", "evidence": [ { "database": "UniProtKB", "id": "Q9VWW1", "url": "https://www.uniprot.org/uniprotkb/Q9VWW1" } ], "pmid": "" }, { "name": "pyrimidine nucleotide biosynthetic process", "id": "GO:0006221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006221", "evidence": [ { "database": "UniProtKB", "id": "Q9VWW1", "url": "https://www.uniprot.org/uniprotkb/Q9VWW1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VWW1", "url": "https://www.uniprot.org/uniprotkb/Q9VWW1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9VWW1", "url": "https://www.uniprot.org/uniprotkb/Q9VWW1" } ], "pmid": "" }, { "name": "cobalt ion binding", "id": "GO:0050897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050897", "evidence": [ { "database": "UniProtKB", "id": "Q9VWW1", "url": "https://www.uniprot.org/uniprotkb/Q9VWW1" } ], "pmid": "" }, { "name": "allantoinase activity", "id": "GO:0004038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004038", "evidence": [ { "database": "UniProtKB", "id": "Q9VWW1", "url": "https://www.uniprot.org/uniprotkb/Q9VWW1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 176, "end_pos": 178, "annotation": "n_glycosylation_sequon" }, { "start_pos": 255, "end_pos": 257, "annotation": "n_glycosylation_sequon" }, { "start_pos": 274, "end_pos": 276, "annotation": "n_glycosylation_sequon" }, { "start_pos": 378, "end_pos": 380, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWW1" }, { "id": "PF01979", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01979" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Amidohydrolase-related", "eco_id": "ECO_0000259", "start_pos": 306, "end_pos": 454, "start_aa": "Glu", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q9VWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWW1" }, { "id": "PF12890", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12890" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Dihydroorotase catalytic", "eco_id": "ECO_0000259", "start_pos": 62, "end_pos": 154, "start_aa": "Val", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.5.2.5", "ec_name": "(S)-allantoin + H2O = allantoate + H(+).", "evidence": [ { "id": "3.5.2.5", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.2.5" }, { "id": "3.5.2.5", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.5.2.5" } ] } ], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 334 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 176, "end_pos": 178 }, { "start_pos": 255, "end_pos": 257 }, { "start_pos": 274, "end_pos": 276 }, { "start_pos": 378, "end_pos": 380 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", 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"url": "https://www.uniprot.org/uniprotkb/Q9VWX6" } ] }, { "name": "CG15064", "type": "synonym", "evidence": [ { "id": "NP_573273", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573273" }, { "id": "Q9VWX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWX6" } ] }, { "name": "Dmel\\CG15064", "type": "synonym", "evidence": [ { "id": "NP_573273", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573273" }, { "id": "Q9VWX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWX6" } ] }, { "name": "Dmel_CG15064", "type": "synonym", "evidence": [ { "id": "Q9VWX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWX6" } ] }, { "name": "Him", "type": "synonym", "evidence": [ { "id": "NP_573273", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573273" } ] }, { "name": "him", "type": "synonym", "evidence": [ { "id": "NP_573273", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573273" }, { "id": "Q9VWX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWX6" } ] } ], "protein_names": [ { "name": "CG15064-PA", "type": "synonym", "evidence": [ { "id": "NP_573273", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573273" } ] }, { "name": "Him-PA", "type": "synonym", "evidence": [ { "id": "NP_573273", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573273" } ] }, { "name": "Holes in muscle", "type": "synonym", "evidence": [ { "id": "Q9VWX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWX6/entry#names_and_taxonomy" } ] }, { "name": "holes in muscles", "type": "synonym", "evidence": [ { "id": "NP_573273", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573273" } ] }, { "name": "holes in muscle", "type": "synonym", "evidence": [ { "id": "NP_573273", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573273" } ] }, { "name": "holes-in-muscle", "type": "synonym", "evidence": [ { "id": "NP_573273", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573273" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VWX6", "url": "https://www.uniprot.org/uniprotkb/Q9VWX6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Him", "url": "https://www.uniprot.org/uniprotkb/Q9VWX6", "locus": { "chromosome": "X", "start_pos": 18210741, "end_pos": 18209427, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0030900", "url": "https://www.ensemblgenomes.org/id/FBgn0030900" } ] } } ], "crossref": [ { "id": "FB:FBgn0030900", "url": "https://alliancegenome.org/gene/FB:FBgn0030900", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0030900", "url": "https://bgee.org/?page=gene&gene_id=FBgn0030900", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0030900", "url": "https://flybase.org/reports/FBgn0030900", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "32801", "url": "https://www.ncbi.nlm.nih.gov/gene/32801", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dme:Dmel_CG15064", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG15064", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KQQRSMD", "url": "https://omabrowser.org/oma/group/KQQRSMD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VWX6", "url": "https://www.orthodb.org/?gene=Q9VWX6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "NP_573273", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573273", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VWX6", "url": "https://www.uniprot.org/uniprotkb/Q9VWX6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VWX6-1", "url": "https://www.uniprot.org/uniprotkb/Q9VWX6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGVIYKILKQQRSMDLSLSSATRCKVQAAIKQRQQQRRLEDHMVEERDRDRERDQQPDQDQNQVQNHIDKDKEELAEQQLQQLCRFLAENAARKKRQRFKLQYQCNLAIDQDNDQEQMPEKEHFAAPPHEMDLEFIEQLQQSSPAKSHGATGQAPRDSILLKIRHQIFERKRQRQRQLAELVQQRMVVWRPW", "length": 192, "header": "tr|Q9VWX6-1|Q9VWX6_DROME Isoform 1 of Holes in muscle OS=Drosophila melanogaster OX=7227 GN=Him PE=4 SV=1 CANONICAL=Q9VWX6-1" }, "isoforms": [ { "isoform_ac": "Q9VWX6-1", "url": "https://www.uniprot.org/uniprotkb/Q9VWX6/entry#Q9VWX6-1", "sequence": { "sequence": "MGVIYKILKQQRSMDLSLSSATRCKVQAAIKQRQQQRRLEDHMVEERDRDRERDQQPDQDQNQVQNHIDKDKEELAEQQLQQLCRFLAENAARKKRQRFKLQYQCNLAIDQDNDQEQMPEKEHFAAPPHEMDLEFIEQLQQSSPAKSHGATGQAPRDSILLKIRHQIFERKRQRQRQLAELVQQRMVVWRPW", "length": 192, "header": "tr|Q9VWX6-1|Q9VWX6_DROME Isoform 1 of Holes in muscle OS=Drosophila melanogaster OX=7227 GN=Him PE=4 SV=1 CANONICAL=Q9VWX6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VWX6", "url": "https://www.uniprot.org/uniprotkb/Q9VWX6" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VWX6", "url": "https://www.uniprot.org/uniprotkb/Q9VWX6" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWX6", "url": "https://www.uniprot.org/uniprotkb/Q9VWX6" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWX6", "url": "https://www.uniprot.org/uniprotkb/Q9VWX6" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": 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"" }, { "id": "MONDO:0007664", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007664", "name": "MYOC juvenile glaucoma", "description": "" }, { "id": "MONDO:0007664", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007664", "name": "MYOC juvenile open angle glaucoma", "description": "" }, { "id": "MONDO:0007664", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007664", "name": "glaucoma 1, open angle, A", "description": "" }, { "id": "MONDO:0007664", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007664", "name": "glaucoma 1, open angle, type A", "description": "" }, { "id": "MONDO:0007664", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007664", "name": "glaucoma 1A, primary open angle", "description": "" }, { "id": "MONDO:0007664", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007664", "name": "juvenile glaucoma caused by mutation in MYOC", "description": "" }, { "id": "MONDO:0007664", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007664", "name": "juvenile open angle glaucoma caused by mutation in MYOC", "description": "" }, { "id": "MONDO:0007664", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007664", "name": "GLC1A", "description": "" }, { "id": "MONDO:0007664", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007664", "name": "glaucoma hereditary, juvenile", "description": "" }, { "id": "MONDO:0007664", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007664", "name": "primary open angle glaucoma juvenile onset 1", "description": "" }, { "id": "MIM:137750", "resource": "MIM", "url": "https://www.omim.org/entry/137750", "name": "Glaucoma 1, open angle, A", "description": "Glaucoma 1, open angle, A" } ], "unlinked_id_list": [], "evidence": [ { "id": "1068", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1068" } ] }, { "disease_id": "DOID:1070", "recommended_name": { "id": "DOID:1070", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1070", "name": "primary open angle glaucoma", "description": "An open-angle glaucoma that is characterized by the absence of any apparent obstruction of aqueous outflow through the trabecular meshwork with gonioscopy, but often with elevated intraocular pressure." }, "synonyms": [ { "id": "DOID:1070", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1070", "name": "chronic simple glaucoma", "description": "" }, { "id": "MONDO:0100553", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0100553", "name": "OPTN-related open angle glaucoma", "description": "Any open angle glaucoma in which the cause of the disease is a mutation in the OPTN gene." }, { "id": "MONDO:0100553", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0100553", "name": "OPTN-related open angle glaucoma", "description": "" }, { "id": "MONDO:0100553", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0100553", "name": "glaucoma 1, open angle, E", "description": "" }, { "id": "MIM:137760", "resource": "MIM", "url": "https://www.omim.org/entry/137760", "name": "Glaucoma, primary open angle", "description": "Glaucoma, primary open angle" } ], "unlinked_id_list": [], "evidence": [ { "id": "1070", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1070" } ] }, { "disease_id": "DOID:13544", "recommended_name": { "id": "DOID:13544", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13544", "name": "low tension glaucoma", "description": "An open-angle glaucoma characterized by increased intrinsic resistance to aqueous outflow without known secondary causes, an anatomically narrow anterior chamber angle, or elevated intraocular pressure compared to the average population. Normal tension glaucoma has_symptom progressive decreased vision and progressive loss of peripheral vision." }, "synonyms": [ { "id": "DOID:13544", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13544", "name": "Normal tension glaucoma", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "13544", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13544" } ] }, { "disease_id": "DOID:2920", "recommended_name": { "id": "DOID:2920", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2920", "name": "membranoproliferative glomerulonephritis", "description": "" }, "synonyms": [ { "id": "DOID:2920", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2920", "name": "Lobular glomerulonephritis", "description": "" }, { "id": "DOID:2920", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2920", "name": "chronic glomerulonephritis, lobular", "description": "" }, { "id": "MONDO:0010596", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010596", "name": "membranoproliferative glomerulonephritis, X-linked", "description": "" }, { "id": "MONDO:0010596", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010596", "name": "membranoproliferative glomerulonephritis, X-linked", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "2920", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2920" } ] }, { "disease_id": "DOID:9282", "recommended_name": { "id": "DOID:9282", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9282", "name": "ocular hypertension", "description": "An eye disease that is characterized by elevated intraocular pressure in the absence of optic nerve damage or visual field loss." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "9282", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9282" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VWZ7", "url": "https://www.uniprot.org/uniprotkb/Q9VWZ7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "CT21241", "url": "https://www.uniprot.org/uniprotkb/Q9VWZ7", "locus": { "chromosome": "X", "start_pos": 18028261, "end_pos": 18023870, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0030887", "url": "https://www.ensemblgenomes.org/id/FBgn0030887" } ] } } ], "crossref": [ { "id": "FB:FBgn0030887", "url": "https://alliancegenome.org/gene/FB:FBgn0030887", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0030887", "url": "https://bgee.org/?page=gene&gene_id=FBgn0030887", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00096", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00096", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0030887", "url": "https://flybase.org/reports/FBgn0030887", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "32782", "url": "https://www.ncbi.nlm.nih.gov/gene/32782", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003112", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003112", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050605", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050605", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG6867", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG6867", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CKCPGRQ", "url": "https://omabrowser.org/oma/group/CKCPGRQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VWZ7", "url": "https://www.orthodb.org/?gene=Q9VWZ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23192", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23192", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23192:SF85", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23192:SF85", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01391", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01391", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02191", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02191", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_573262", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573262", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VWZ7", "url": "https://www.uniprot.org/uniprotkb/Q9VWZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VWZ7-1", "url": "https://www.uniprot.org/uniprotkb/Q9VWZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFLAVNQSLQNTSKKKRKRRTAEDDPQEDSGEGTPPVRPLEPSASSDQLVGVGNGATCRVCKCPGRQSLTLVYIYLGALTLILASLSIVFYTHTQDVESLSQVEDNYSSKSFRVQFQAELMRSEEELRRLVNRIIEEEQELVGSTTASSTTQSRDPLKNERKFTDNLISHTTRPTGKRMRRDIASSAPASMHADPLIEFFNPNHRKVLEEQDTEIRKRTGQKGAAPGGDEWIYLNTYCRVPEKIITGFCKGTQDYCPPAPQGPTGEVGPKGPPGNPGLPGIPGPKGNRGDVGLPGAPGVDGVGHLGPAGPRGPKGDAGATGRAGLDGRDGVPGEPGLDGVPGRAGADGKNGLPGRDGKDGLHGKDGKDGLSITGPKGAQGPPGERGLKGIAGPRGRPGKPGTNGIPGVPGINAWKLQYPNGSSSNDLLIPPSITDIQVPDFQRTVIVEEGRSLNLSCTATGTPTPQVEWRREDGRTINVNGVEMASISGQFLRFTNITRHQMAAYTCFANNGIAPVANATYLVEVQFAPMISVYRQMIYAEYQSSATLECLVEAFPEAIRYWERAYDGKILDPSDKYGIESYPEGFKTTMRLTISNLRKDDFGYYHCVARNELNATMVNFEIAPQDPNSETPYVGNNMKVYGQRPPESECPVCDQCPDPSLYQCKDSILNNFEIQATGNLSYPGLPKRPKTCYLYAVGKPVFHKVVNEKFGSWLRDPSPDSDREKTFVTNENDPYNLFEFTTRIQYRMNSIPRRKYEIQEGFHGNAHVVFNGSFYYQQRNSDLVVKLDLTSLKKITTQLPYAGVAAANRLYTTDYNYMDFNVDEVGLWVIYSTYNSNNTLVAKLDAETLKMQYNFNITLDHHQFGEMFIVCGNLYAIDSGTDKNTQIRYVVDLYKGKLLNTNLPFSNPFSHTTTVGYNPLTVELYSWDKGNALTYPIRYNEQRLISDNS", "length": 949, "header": "tr|Q9VWZ7-1|Q9VWZ7_DROME Isoform 1 of Colmedin OS=Drosophila melanogaster OX=7227 GN=CT21241 PE=4 SV=2 CANONICAL=Q9VWZ7-1" }, "isoforms": [ { "isoform_ac": "Q9VWZ7-1", "url": "https://www.uniprot.org/uniprotkb/Q9VWZ7/entry#Q9VWZ7-1", "sequence": { "sequence": "MFLAVNQSLQNTSKKKRKRRTAEDDPQEDSGEGTPPVRPLEPSASSDQLVGVGNGATCRVCKCPGRQSLTLVYIYLGALTLILASLSIVFYTHTQDVESLSQVEDNYSSKSFRVQFQAELMRSEEELRRLVNRIIEEEQELVGSTTASSTTQSRDPLKNERKFTDNLISHTTRPTGKRMRRDIASSAPASMHADPLIEFFNPNHRKVLEEQDTEIRKRTGQKGAAPGGDEWIYLNTYCRVPEKIITGFCKGTQDYCPPAPQGPTGEVGPKGPPGNPGLPGIPGPKGNRGDVGLPGAPGVDGVGHLGPAGPRGPKGDAGATGRAGLDGRDGVPGEPGLDGVPGRAGADGKNGLPGRDGKDGLHGKDGKDGLSITGPKGAQGPPGERGLKGIAGPRGRPGKPGTNGIPGVPGINAWKLQYPNGSSSNDLLIPPSITDIQVPDFQRTVIVEEGRSLNLSCTATGTPTPQVEWRREDGRTINVNGVEMASISGQFLRFTNITRHQMAAYTCFANNGIAPVANATYLVEVQFAPMISVYRQMIYAEYQSSATLECLVEAFPEAIRYWERAYDGKILDPSDKYGIESYPEGFKTTMRLTISNLRKDDFGYYHCVARNELNATMVNFEIAPQDPNSETPYVGNNMKVYGQRPPESECPVCDQCPDPSLYQCKDSILNNFEIQATGNLSYPGLPKRPKTCYLYAVGKPVFHKVVNEKFGSWLRDPSPDSDREKTFVTNENDPYNLFEFTTRIQYRMNSIPRRKYEIQEGFHGNAHVVFNGSFYYQQRNSDLVVKLDLTSLKKITTQLPYAGVAAANRLYTTDYNYMDFNVDEVGLWVIYSTYNSNNTLVAKLDAETLKMQYNFNITLDHHQFGEMFIVCGNLYAIDSGTDKNTQIRYVVDLYKGKLLNTNLPFSNPFSHTTTVGYNPLTVELYSWDKGNALTYPIRYNEQRLISDNS", "length": 949, "header": "tr|Q9VWZ7-1|Q9VWZ7_DROME Isoform 1 of Colmedin OS=Drosophila melanogaster OX=7227 GN=CT21241 PE=4 SV=2 CANONICAL=Q9VWZ7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VWZ7", "url": "https://www.uniprot.org/uniprotkb/Q9VWZ7" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VWZ7", "url": "https://www.uniprot.org/uniprotkb/Q9VWZ7" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWZ7", "url": "https://www.uniprot.org/uniprotkb/Q9VWZ7" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWZ7", "url": "https://www.uniprot.org/uniprotkb/Q9VWZ7" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VWZ7", "url": "https://www.uniprot.org/uniprotkb/Q9VWZ7" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VWZ7", "url": "https://www.uniprot.org/uniprotkb/Q9VWZ7" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VWZ7", "url": "https://www.uniprot.org/uniprotkb/Q9VWZ7" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWZ7", "url": "https://www.uniprot.org/uniprotkb/Q9VWZ7" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VWZ7", "url": "https://www.uniprot.org/uniprotkb/Q9VWZ7" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VWZ7", "url": "https://www.uniprot.org/uniprotkb/Q9VWZ7" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VWZ7", "url": "https://www.uniprot.org/uniprotkb/Q9VWZ7" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG6867", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG6867", "resource": "KEGG Pathway" }, { "id": "R-DME-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M9P157-1", "protein_name": "Gliomedin isoform X1", "gene_name": "gldn", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLDPLAELRRTGGFRQCGGRMSWQFRWMLYSVCILTVINCAGLVLLLVQQRDLWAQLIEVERQMVEISQSSVVEFMTQVNEDEAEYQYSRNKRRRQHRGTRPFEEHEGSVGEEVLSDFQYSFQQPPGPVYQHKTEEKDGMMMMMTYSMVPVKILLDICNSTKGVCLTGPPGPPGIAGIPGVDGMPGYNGTDGIPGLPGEPGAHGKRGKRGPSGEKGEPGEKGEPGYPGPPGPPGEQGEPSNDVIIEGPPGPMGPSGPPGPPGPPGPPGPQGPPRHRSHRAHLPIGKESVGHLNSVPNDDTLSQKLASWKTNDCVIKSVQNPRHLMKTSSTFGAWMMDTAAHDDEKIWVAEHFSGRLIKEYNSIAAFQNSSSESIDVRRFFQGCGHAVHNGSIFYHIAGTSNIAKFDLQTKILHVLSIENALYHNLSYLLQNSKTYFKLAADENGMWIVFASNIDDSIMVARLDEKTFSVSTYINTTYPRTKAGSVFIACGILYVTDTKDTKVTYAFDLLKEKPVSASLDLRAPGGVLSMISYNPRDKHLYIWDSSYVKSYQVQFLSDSNQESVK", "length": 564 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050119-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050119-4#orthology", "database": "AGR" }, { "id": "MGI:2388361", "url": "https://alliancegenome.org/gene/MGI:2388361#orthology", "database": "AGR" }, { "id": "FB:FBgn0030887", "url": "https://alliancegenome.org/gene/FB:FBgn0030887#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7UVJ6-1", "protein_name": "Olfactomedin-like protein 2B isoform X2", "gene_name": "olfml2bb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGLLLYIFCCVFCLTRANVEQQATDNTDNRATLEDEMDNQENILTQLIGDYDKVKTLSEGSDCQCKCVVRPLSRSACKRIEEGQAKTEDFYTVETVTAGPNCKKCACIAPPSALNPCEGDFRFKKLQEAGQDDIKLSNIMDLLEGSFYGMDLLKLHSVTTKLLERVDNIEKSFSGNLTKEKVSVKGEKGQGKGARSNQRQEKKKRLSVLEPSLQKNAAAAFAHTERKYEEKFVGNQGPSKPVLKKSKSEGQEEQHKPAKTKADAKNMSLRSMTFYKANRMEDSEGEERIGATVAHEVVSGDESVDLIIEDQLHKQGLNTPVTTPEATVTVTQSTTINLNTQNFTTARMSNVTKQTQGQSVKAMMSSTITTERPTMPTSTTSTSTMTPGTNTTTIATPLVVPKQLASVTVPIKKSKLSWDEVTTQKSTTTLKTKDHGICKDTLASISDPVTHNKYGKNEGAWMKDPKGNGKVVYVTDYYYGNQLLEFRDIDTFKQGQVSNSYKLPYNWIGTGHVVYSGSFFYNRAFSRDIIRFDLRLRYVAAWTTLHDAILEEEEAPWTWGGHSDIDFSVDESGLWLVYPALDDEGFHQEVIILSKLRASDLQKEKSWRTGLRRNYYGNCFVICGVLYAVDSFERTHANISYAFDTHTHTQMIPRLPFINNYTYTTQIDYNPKERMLYAWDNGHQVTYDVIFAY", "length": 693 }, "evidence": [ { "id": "HGNC:24558", "url": "https://alliancegenome.org/gene/HGNC:24558#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A2AWU1-1", "protein_name": "Olfactomedin 1a isoform 1", "gene_name": "olfm1a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSVPLLKIGVVLSTMAMITNWMSQTLPSLVGLNSTKLSVAPPGVPDRSTGVLPANPEESWQVYSSAQDSEGRCVCTVVAPQQTMCSRDARTKQLRQLLEKVQNMTQSIQNLDQRTQKDLQYVQRMEVQLRGLETKFKQVEESHKQNIAKQYKAIKAKMEELRPMIPVLEEYKADAKLVMQFKEEVKNLTSVLSELQEEIGAFDYEELHNRVSNLEERLRACMQKLACGKLTGISDAITIKTSGSRYGSWMTDPLAPDGDTRVWYMDGYHNNRFVREYKSMADFMYSDNFTSHRLPHPWSGTGQVVYNGSIYFNKFQSNTIIKFDFKTATISKSGQLDYAGFNNRYHYSWGGHSDIDLMVDEGGLWAIYATNQNAGNIVISKLNPATLQIVKSYTTNHPKRSAGEAFMICGTLYVTNGYSGGTKVYYAFHTNSSTYEYIDIPLQNKYSHISMLDYNPRDRALYAWNNGHQVLYNVTLFHVIRSEEL", "length": 485 }, "evidence": [ { "id": "MGI:1860437", "url": "https://alliancegenome.org/gene/MGI:1860437#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "B7ZD15-1", "protein_name": "Olfactomedin 1b isoform 1", "gene_name": "olfm1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSVPLLKIGVVLSTMAMITNWMSQTLPSLVGLNTTKLTAAQGGYPDRSIGVLPANPEESWQVYSSAQDSEGRCVCTVVAPQQTMCSRDARTKQLRQLLEKVQNMTQSIQVLDQRTQRDLQYVVKMEDQLRGLETKFRQVEENHKQNIAKQYKAIKAKMAELRPLIPVLEEYKADARLVQQFKEEVQNLTASLGLLQQEMGAYDYDDLHSRVVSLEERLRACMQKLACGKLTGISDAITIKTSGSRFGSWMTDPLAPEGDTRVWYMDGYHNNRFVREYKSMADFMTSDNFTSHRLPHPWSGTGQVVYNGSIYFNKFQSNMIIKFDFKTSTMSKSQRLDNAGFSNTYHYAWGGHSDIDLMVDEGGLWAVYATNQNAGNIVISKLHPITLHIIQSWTTNHPRRSAGESFMICGTLYVTNGYSGGTKVYYAYHTNSSTYEYIDIVLQNKYSHISMLDYNPRDRALYAWNNGHQVLYNVTLFHVIRSEQL", "length": 485 }, "evidence": [ { "id": "MGI:1860437", "url": "https://alliancegenome.org/gene/MGI:1860437#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D4A0J7-1", "protein_name": "Olfactomedin-like 2B", "gene_name": "Olfml2b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAYPLPLVLCFALVVARVWGSSTPPTGTSEPPDVQTVAPTEDDVLQNEADNQENVLSQLLGDYDKVKAVSEGSDCQCKCVVRPLGRDACQRINEGASRKEDFYTVETITSGSSCKCACVAPPSAVNPCEGDFRLQKLREADSRDLKLSTIIDMLEGAFYGLDLLKLHSVTTKLVGRVDKLEEEVSKNLTKENEQIKEDVEEIRTELNKRGKENCSDNILGNMPDIRSALQRDAAAAYAHPEEQYEERFLQEETVSQQINSIELLRTQPLAPPTVMKPRQPSQRQVHLRGRLASKPTVIRGITYYKAKVSEEENDIEDQHDELFSGDSGVDLLIEDQLLRQEDLLMSATRRPATTRHAAAVSTDASVQATALSSEPAQASASAPSLVDPASQAPDRQLLASPQTTTVSPETMGVMPSTQVSPTTVAHTAIQPPPAMIPGDIFVEALHLVPMSPDTVGTDMAEEEGTARQEATSASPILSPEEEDDIRNVIGRCKDTLSTITGPTTQNTYGRNEGAWMKDPLAKDDRIYVTNYYYGNTLVEFRNLENFKQGRWSNSYKLPYSWIGTGHVVYNGAFYYNRAFTRNIIKYDLKQRYVAAWAMLHDVAYEETTPWRWQGHSDVDFAVDENGLWLIYPALDDEGFSQEVIVLSKLNAVDLSTQKETTWRTGLRRNFYGNCFVICGVLYAVDSYNQRNANISYAFDTHTNTQIVPRLLFENEYSYTTQIDYNPKDRLLYAWDNGHQVTYHVIFAY", "length": 748 }, "evidence": [ { "id": "HGNC:24558", "url": "https://alliancegenome.org/gene/HGNC:24558#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1R5K6-1", "protein_name": "Noelin-2a isoform X1", "gene_name": "olfm2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSVPLLKIGAVLSTMAMVTNWMSQTLPSLVGLNGTTISRAGTSERIVSALYPSPEEGWQIYSSAQDADGKCICTVVAPAQNMCNRDPRSRQLRQLMEKVQNITQSMEVLDLRTYRDLQYVRDTENLMKTVDGKLKTASENPRSLNPKSFQELKDKVTQLLPLLPVLEQYKADARMILRLREEVRNLSLVLMAIQEEMGAYDYEELRQRVLLLETRLHSCMQKLGCGKLTGVSNPITVRASGSRFGSWMTDTMIPSSDNRVWSMDGYFKGRRVLEYRTMNDFMKGQNFVQHLLPHPWAGTGHVVYNGSLYYNKYQSNILIKYHFRSRSVLVQRSLSGAGYNNTFPYSWGGSSDIDLMADENGLWAVYTTIPNAGNIVISRLEPQSLEVLQTWDTGFPKRSAGESFMICGTLYVTNSHLAGAKIYFAYYTNTSTYEYTDIPFHNQYSHISMMDYNPRERVLYTWNNGHQVLYNVTLFQVIKTAED", "length": 483 }, "evidence": [ { "id": "MGI:3045350", "url": "https://alliancegenome.org/gene/MGI:3045350#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O70624-1", "protein_name": "Myocilin", "gene_name": "Myoc", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPALHLLFLACLVWGMGARTAQFRKANDRSGRCQYTFTVASPNESSCPREDQAMSAIQDLQRDSSIQHADLESTKARVRSLESLLHQMTLGRVTGTQEAQEGLQGQLGALRRERDQLETQTRDLEAAYNNLLRDKSALEEEKRQLEQENEDLARRLESSSEEVTRLRRGQCPSTQYPSQDMLPGSREVSQWNLDTLAFQELKSELTEVPASQILKENPSGRPRSKEGDKGCGALVWVGEPVTLRTAETIAGKYGVWMRDPKPTHPYTQESTWRIDTVGTEIRQVFEYSQISQFEQGYPSKVHVLPRALESTGAVVYAGSLYFQGAESRTVVRYELDTETVKAEKEIPGAGYHGHFPYAWGGYTDIDLAVDESGLWVIYSTEEAKGAIVLSKLNPANLELERTWETNIRKQSVANAFVICGILYTVSSYSSAHATVNFAYDTKTGTSKTLTIPFTNRYKYSSMIDYNPLERKLFAWDNFNMVTYDIKLLEM", "length": 490 }, "evidence": [ { "id": "HGNC:7610", "url": "https://alliancegenome.org/gene/HGNC:7610#orthology", "database": "AGR" }, { "id": "RGD:620430", "url": "https://alliancegenome.org/gene/RGD:620430#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O88998-1", "protein_name": "Noelin", "gene_name": "Olfm1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVPLLKIGVVLSTMAMITNWMSQTLPSLVGLNTTRLSAASGGTLDRSTGVLPTNPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLEKVQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLETKFKQVEESHKQHLARQFKAIKAKMDELRPLIPVLEEYKADAKLVLQFKEEVQNLTSVLNELQEEIGAYDYDELQSRVSNLEERLRACMQKLACGKLTGISDPVTVKTSGSRFGSWMTDPLAPEGDNRVWYMDGYHNNRFVREYKSMVDFMNTDNFTSHRLPHPWSGTGQVVYNGSIYFNKFQSHIIIRFDLKTEAILKTRSLDYAGYNNMYHYAWGGHSDIDLMVDENGLWAVYATNQNAGNIVISKLDPVSLQILQTWNTSYPKRSAGEAFIICGTLYVTNGYSGGTKVHYAYQTNASTYEYIDIPFQNKYSHISMLDYNPKDRALYAWNNGHQTLYNVTLFHVIRSDEL", "length": 485 }, "evidence": [ { "id": "MGI:1860437", "url": "https://alliancegenome.org/gene/MGI:1860437#orthology", "database": "AGR" }, { "id": "FB:FBgn0030887", "url": "https://alliancegenome.org/gene/FB:FBgn0030887#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O95897-1", "protein_name": "Noelin-2", "gene_name": "OLFM2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWPLTVPPPLLLLLCSGLAGQTLFQNPEEGWQLYTSAQAPDGKCICTAVIPAQSTCSRDGRSRELRQLMEKVQNVSQSMEVLELRTYRDLQYVRGMETLMRSLDARLRAADGSLSAKSFQELKDRMTELLPLSSVLEQYKADTRTIVRLREEVRNLSGSLAAIQEEMGAYGYEDLQQRVMALEARLHACAQKLGCGKLTGVSNPITVRAMGSRFGSWMTDTMAPSADSRVWYMDGYYKGRRVLEFRTLGDFIKGQNFIQHLLPQPWAGTGHVVYNGSLFYNKYQSNVVVKYHFRSRSVLVQRSLPGAGYNNTFPYSWGGFSDMDFMVDESGLWAVYTTNQNAGNIVVSRLDPHTLEVMRSWDTGYPKRSAGEAFMICGVLYVTNSHLAGAKVYFAYFTNTSSYEYTDVPFHNQYSHISMLDYNPRERALYTWNNGHQVLYNVTLFHVISTSGDP", "length": 454 }, "evidence": [ { "id": "MGI:3045350", "url": "https://alliancegenome.org/gene/MGI:3045350#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3V1G4-1", "protein_name": "Olfactomedin-like protein 2B", "gene_name": "Olfml2b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAYPLPLVLCFALVVAQVWGSTTPPTGTSEPPDVQTVEPTEDDILQNEADNQENVLSQLLGDYDKVKAVSEGSDCQCKCVVRPLGRDACQRINQGASRKEDFYTVETITSGSSCKCACVAPPSAVNPCEGDFRLQKLREADSRDLKLSTIIDLLEGAFYGLDLLKLHSVTTKLVGRVDKLEEEVSKNLTKENEQIKEDVEEIRTELNKRGKENCSDNTLESMPDIRSALQRDAAAAYAHPEYEERFLQEETVSQQINSIELLRTQPLVPPAAMKPQRPLQRQVHLRGRLASKPTVIRGITYYKAKVSEEENDIEEQHDELFSGDSGVDLLIEDQLLRQEDLLTSATRRPATTRHTAAVTTDASIQAAASSSEPAQASASASSFVEPAPQASDRELLATPQTTTVFPEPTEVMPSTQVSPTTVAHTAVQPLPAMVPGDIFVEALPLVPLLPDTVGTDMPEEEGTAGQEATSAGPILSPEEEDDIRNVIGRCKDTLSTITGPTTQNTYGRNEGAWMKDPLAKDDRIYVTNYYYGNTLVEFRNLENFKQGRWSNSYKLPYSWIGTGHVVYNGAFYYNRAFTRNIIKYDLKQRYVAAWAMLHDVAYEEATPWRWQGHSDVDFAVDENGLWLIYPALDDEGFNQEVIVLSKLNAVDLSTQKETTWRTGLRRNFYGNCFVICGVLYAVDSYNQRNANISYAFDTHTNTQIVPRLLFENEYSYTTQIDYNPKDRLLYAWDNGHQVTYHVIFAY", "length": 746 }, "evidence": [ { "id": "HGNC:24558", "url": "https://alliancegenome.org/gene/HGNC:24558#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q568Y7-1", "protein_name": "Noelin-2", "gene_name": "Olfm2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVPLLKIGAVLSTMAMVTNWMSQTLPSLVGLNSTVSRAGSSEKITLFQSPEEGWQLYTSAQAPDGKCICTAVIPAQSTCARDGRSRELRQLMEKVQNVSQSMEVLELRTYRDLQYVRSMETLMRSLDARLRTADGSVSAKSFQELKDRMTELLPLSSVLEQYKADTRTIVRLREEVRNLSGNLAAIQEEMGAYGYEDLQQRVMALEARLHACAQKLGCGKLTGVSNPITIRAMGSRFGSWMTDTMAPSADSRVWYMDGYYKGRRVLEFRTLGDFIKGQNFIQHLLPQPWAGTGHVVYNGSLFYNKYQSNVVVKYHFRSRSVLVQRSLPGAGYNNTFPYSWGGFSDMDFMVDESGLWAVYTTNQNAGNIVVSRLDPHTLEVVRSWDTGYPKRSAGEAFMICGVLYVTNSHLAGAKVYFAYFTNTSSYEYTDVPFHNQYSHISMLDYNPRERALYTWNNGHQVLYNVTLFHVISTAGDP", "length": 478 }, "evidence": [ { "id": "MGI:3045350", "url": "https://alliancegenome.org/gene/MGI:3045350#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5RH76-1", "protein_name": "Olfactomedin-like 2Ba precursor", "gene_name": "olfml2ba", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTEMKIWCVLLMAFALTSAAPKSHLRLEEKTKDNNDTLQVEIDNQEHILSQLLGDYDKVKALSEGSDCGCKCVVRPLSASACQRIREGHATPQDFYTVETITSGPHCKCACIAPPSALNPCEGDFRLKKLRQAGKDNIKLSTILELLEGSFYGMDLLKLHSVTTKILDRMDTIEKMVLNNQTEEKLNTISTSPNPQLSTSSPTTLPSVIQEKRTSLREQNDEAAAFQHMEYYSVLKCTQQSKYEEKFVGDILNSGSDLNKATTALQEQEQQGRKKQPKITVRGITYYRSDPVDEMDSEKNLDDNLSGDSPIDLFADEQLLRHKARHFRPVIKAWSVRPKTKSEISKGGDAPKKHQNPLMGLLDSTALPIKTPTEPITVQTQTSHSTTDSSTGDERTTTTPAAMDNLKVTKSSIKRMEANKVEPPTPSVQQAQNMLVRSSNLGHIKTNESVAAAVKVEATEPTMTNQTNGTAVKETSASSVTQTGALIKEHLKASTQSTLNTLTPSPTSHSNALTVTESSVGINAHKGEVTTIVMTASVTGSKTDSVTDLTQLSPRVRETLTTTRTTTKTATTSQPVKRKYSISWDEEEEAVVPEQVEEEKAVKPVVEDKVGEEPQRKPGMCKDTLATISEPITHNTYGRNEGAWMKDPLDQDDKIYVTNYYYGNNLLEFRNIDVFKQGRFTNSYKLPYNWIGTGHVVYKGAFYYNRAFSRDIIKFDLRLRYVAAWTMLHDAVFENDDVSSWRWRGNSDMDLAIDESGLWVIYPALDDEGFLQEVIVLSRLNPTDLSMKRETTWRTGLRRNRYGNCFIVCGVLYATDSYNQQDTNLSYAFDTHTNTQVIPHLPFSNNYTYVTQIDYNPKERVLYAWDNGHQVTYNVQFAYVDPL", "length": 883 }, "evidence": [ { "id": "HGNC:24558", "url": "https://alliancegenome.org/gene/HGNC:24558#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q62609-1", "protein_name": "Noelin", "gene_name": "Olfm1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVPLLKIGVVLSTMAMITNWMSQTLPSLVGLNTTRLSAASGGTLDRSTGVLPTNPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLEKVQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLESKFRQVEESHKQHLARQFKAIKAKMDELRPLIPVLEEYKADAKLVLQFKEEVQNLTSVLNELQEEIGAYDYDELQSRVSNLEERLRACMQKLACGKLTGISDPVTVKTSGSRFGSWMTDPLAPEGDNRVWYMDGYHNNRFVREYKSMVDFMNTDNFTSHRLPHPWSGTGQVVYNGSIYFNKFQSHIIIRFDLKTETILKTRSLDYAGYNNMYHYAWGGHSDIDLMVDENGLWAVYATNQNAGNIVISKLDPVSLQILQTWNTSYPKRSAGEAFIICGTLYVTNGYSGGTKVHYAYQTNASTYEYIDIPFQNKYSHISMLDYNPKDRALYAWNNGHQTLYNVTLFHVIRSDEL", "length": 485 }, "evidence": [ { "id": "MGI:1860437", "url": "https://alliancegenome.org/gene/MGI:1860437#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q68BL8-1", "protein_name": "Olfactomedin-like protein 2B", "gene_name": "OLFML2B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKPRLLVLYFALIVVPAWVSSIVLTGTSEPPDAQTVAPAEDETLQNEADNQENVLSQLLGDYDKVKAMSEGSDCQCKCVVRPLGRDACQRINAGASRKEDFYTVETITSGSSCKCACVAPPSALNPCEGDFRLQKLREADSQDLKLSTIIDMLEGAFYGLDLLKLHSVTTKLVGRVDKLEEEVSKNLTKENEQIKEDMEEIRTEMNKRGKENCSENILDSMPDIRSALQRDAAAAYAHPEYEERFLQEETVSQQINSIELLQTRPLALPEVVKSQRPLQRQVHLRGRPASQPTVIRGITYYKAKVSEEENDIEEQQDEFFSGDNGVDLLIEDQLLRHNGLMTSVTRRPAATRQGHSTAVTSDLNARTAPWSSALPQPSTSDPSIANHASVGPTLQTTSVSPDPTRESVLQPSPQVPATTVAHTATQQPAAPAPPAVSPREALMEAMHTVPVPPTTVRTDSLGKDAPAGWGTTPASPTLSPEEEDDIRNVIGRCKDTLSTITGPTTQNTYGRNEGAWMKDPLAKDERIYVTNYYYGNTLVEFRNLENFKQGRWSNSYKLPYSWIGTGHVVYNGAFYYNRAFTRNIIKYDLKQRYVAAWAMLHDVAYEEATPWRWQGHSDVDFAVDENGLWLIYPALDDEGFSQEVIVLSKLNAADLSTQKETTWRTGLRRNFYGNCFVICGVLYAVDSYNQRNANISYAFDTHTNTQIVPRLLFENEYSYTTQIDYNPKDRLLYAWDNGHQVTYHVIFAY", "length": 750 }, "evidence": [ { "id": "HGNC:24558", "url": "https://alliancegenome.org/gene/HGNC:24558#orthology", "database": "AGR" }, { "id": "FB:FBgn0030887", "url": "https://alliancegenome.org/gene/FB:FBgn0030887#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6ZMI3-1", "protein_name": "Gliomedin", "gene_name": "GLDN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARGAEGGRGDAGWGLRGALAAVALLSALNAAGTVFALCQWRGLSSALRALEAQRGREQREDSALRSFLAELSRAPRGASAPPQDPASSARNKRSHSGEPAPHIRAESHDMLMMMTYSMVPIRVMVDLCNSTKGICLTGPSGPPGPPGAGGLPGHNGLDGQPGPQGPKGEKGANGKRGKMGIPGAAGNPGERGEKGDHGELGLQGNEGPPGQKGEKGDKGDVSNDVLLAGAKGDQGPPGPPGPPGPPGPPGPPGSRRAKGPRQPSMFNGQCPGETCAIPNDDTLVGKADEKASEHHSPQAESMITSIGNPVQVLKVTETFGTWIRESANKSDDRIWVTEHFSGIMVKEFKDQPSLLNGSYTFIHLPYYFHGCGHVVYNNSLYYHKGGSNTLVRFEFGQETSQTLKLENALYFDRKYLFANSKTYFNLAVDEKGLWIIYASSVDGSSILVAQLDERTFSVVQHVNTTYPKSKAGNAFIARGILYVTDTKDMRVTFAFDLLGGKQINANFDLRTSQSVLAMLAYNMRDQHLYSWEDGHLMLYPVQFLSTTLNQ", "length": 551 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050119-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050119-4#orthology", "database": "AGR" }, { "id": "MGI:2388361", "url": "https://alliancegenome.org/gene/MGI:2388361#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80WL1-1", "protein_name": "Gliomedin", "gene_name": "Gldn", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTRAAERGQGATGWGLRGALMAVALLSVLNAVGTVFVLYQWRELSAALRALEAQHGQEQREDSALRAFLAELSRAPARVPEPPQDPMSAARNKRSHGGEPASHIRAESQDMMMMMTYSMVPIRVMIDLCNSTQGICLTGPPGPPGPPGAGGLPGHNGSDGQPGLQGPKGEKGAVGKRGKMGLPGATGNPGEKGEKGDAGELGLPGNEGPPGQKGDKGDKGDVSNDVLLTGAKGDQGPPGPPGPPGPPGPPGSRRAKGPRQPNSFTNQCPGETCVIPNDDTLVGRADEKVNERHSPQTEPMITSIGNPAQVLKVKETFGTWLRESANRSDDRIWVTEHFSGIMVKEFEDLPALLNSSFTLLHLPHYFHGCGHAVYNNSLYYHKGGSNTIVRFEFGKETPQTLKLEDALYFDRKYLFANSKTYFNIAVDEKGLWIIYASSVDGSSILVAQLDERTFSVLRHINTTYPKSKAGNAFIAQGILYVTDTKDTRVTFAFDLLRGKQINANFGLRMSQSVLAMLSYNMRDQHLYSWEDGHLMLYPVHFSSTAPSQR", "length": 549 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050119-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050119-4#orthology", "database": "AGR" }, { "id": "MGI:2388361", "url": "https://alliancegenome.org/gene/MGI:2388361#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BM13-1", "protein_name": "Noelin-2", "gene_name": "Olfm2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRKLRQTGTTIAGGQTLFQSPEEGWQLYTSAQAPDGKCVCTAVIPAQSTCARDGRSRELRQLMEKVQNVSQSMEVLELRTFRDLQYVRSMETLMRSLDARLRAADGSVSAKSFQELKDRMTELLPLSSVLEQYKADTRTIVRLREEVRNLSGNLAAIQEEMGAYGYEDLQQRVMALEARLHACAQKLGCGKLTGVSNPITIRAMGSRFGSWMTDTMAPSADSRVWYMDGYYKGRRVLEFRTLGDFIKGQNFIQHLLPQPWAGTGHVVYNGSLFYNKYQSNVVVKYHFRSRSVLVQRSLPGAGYNNTFPYSWGGFSDMDFMVDESGLWAVYTTNQNAGNIVVSRLDPHTLEVVRSWDTGYPKRSAGEAFMICGVLYVTNSHLAGAKVYFAYFTNTSSYEYTDVPFHNQYSHISMLDYNPRERALYTWNNGHQVLYNVTLFHVISTAGDP", "length": 448 }, "evidence": [ { "id": "MGI:3045350", "url": "https://alliancegenome.org/gene/MGI:3045350#orthology", "database": "AGR" }, { "id": "FB:FBgn0030887", "url": "https://alliancegenome.org/gene/FB:FBgn0030887#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8BMF8-1", "protein_name": "Gliomedin", "gene_name": "Gldn", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTRAAERGQGATGWGLRGALVAIALLSALNAAGTVFVLCQWRGLSAALRALEAQRGREQREDSALRAFLAELSRAPGRVPEPSQDPMSAARNKRSHNGEPASHIRAESQDMMMMMTYSMVPIRVMIDLCNSTQGICLTGPPGPPGPPGAGGLPGHNGSDGQPGLQGPKGEKGAIGKRGKMGLPGATGNPGEKGEKGDAGELGLPGNEGPPGQKGDKGDKGDVSNDVLLTGAKGDQGPPGPPGPPGPPGPPGSRRSKGPRPPNVFNSQCPGETCVIPNDDTLVGRADEKANERHSPQTESMITSIGNPAQVLKVRETFGTWMRESANKSDDRIWVTEHFSGIMVKEFKDLPALLNSSFTLLHLPHYFHGCGHAVYNNSLYYHKGGSNTIVRFEFGKETPQTLKLENALYFDRKYLFANSKTYFNIAVDEKGIWIIYASSVDGSSILVAQLDERTFSVTQHINTTYPKSKAGNAFIARGILYVTDTKDTRVTFAFDLLGGKQINANFDFRMSQSVLAMLSYNMRDQHLYSWEDGHLMLYPVQFLSAASSQR", "length": 549 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050119-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050119-4#orthology", "database": "AGR" }, { "id": "MGI:2388361", "url": "https://alliancegenome.org/gene/MGI:2388361#orthology", "database": "AGR" }, { "id": "FB:FBgn0030887", "url": "https://alliancegenome.org/gene/FB:FBgn0030887#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q99784-1", "protein_name": "Noelin", "gene_name": "OLFM1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSVPLLKIGVVLSTMAMITNWMSQTLPSLVGLNTTKLSAAGGGTLDRSTGVLPTNPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLEKVQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLESKFKQVEESHKQHLARQFKAIKAKMDELRPLIPVLEEYKADAKLVLQFKEEVQNLTSVLNELQEEIGAYDYDELQSRVSNLEERLRACMQKLACGKLTGISDPVTVKTSGSRFGSWMTDPLAPEGDNRVWYMDGYHNNRFVREYKSMVDFMNTDNFTSHRLPHPWSGTGQVVYNGSIYFNKFQSHIIIRFDLKTETILKTRSLDYAGYNNMYHYAWGGHSDIDLMVDESGLWAVYATNQNAGNIVVSRLDPVSLQTLQTWNTSYPKRSAGEAFIICGTLYVTNGYSGGTKVHYAYQTNASTYEYIDIPFQNKYSHISMLDYNPKDRALYAWNNGHQILYNVTLFHVIRSDEL", "length": 485 }, "evidence": [ { "id": "MGI:1860437", "url": "https://alliancegenome.org/gene/MGI:1860437#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99972-1", "protein_name": "Myocilin", "gene_name": "MYOC", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRFFCARCCSFGPEMPAVQLLLLACLVWDVGARTAQLRKANDQSGRCQYTFSVASPNESSCPEQSQAMSVIHNLQRDSSTQRLDLEATKARLSSLESLLHQLTLDQAARPQETQEGLQRELGTLRRERDQLETQTRELETAYSNLLRDKSVLEEEKKRLRQENENLARRLESSSQEVARLRRGQCPQTRDTARAVPPGSREVSTWNLDTLAFQELKSELTEVPASRILKESPSGYLRSGEGDTGCGELVWVGEPLTLRTAETITGKYGVWMRDPKPTYPYTQETTWRIDTVGTDVRQVFEYDLISQFMQGYPSKVHILPRPLESTGAVVYSGSLYFQGAESRTVIRYELNTETVKAEKEIPGAGYHGQFPYSWGGYTDIDLAVDEAGLWVIYSTDEAKGAIVLSKLNPENLELEQTWETNIRKQSVANAFIICGTLYTVSSYTSADATVNFAYDTGTGISKTLTIPFKNRYKYSSMIDYNPLEKKLFAWDNLNMVTYDIKLSKM", "length": 504 }, "evidence": [ { "id": "HGNC:7610", "url": "https://alliancegenome.org/gene/HGNC:7610#orthology", "database": "AGR" }, { "id": "RGD:620430", "url": "https://alliancegenome.org/gene/RGD:620430#orthology", "database": "AGR" }, { "id": "FB:FBgn0030887", "url": "https://alliancegenome.org/gene/FB:FBgn0030887#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9R1J4-1", "protein_name": "Myocilin", "gene_name": "Myoc", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPSCAYCCSCGPKMPALQLLFLACLVWGMGARTAQFRKANDRSGRCQYTFTVASPSESSCPREDQAMSAIQDLQRDSSIQHADLESTKARVRSLESLLHQMTSGGVTGTQEVQEGLQGQLGALRRERDQLETQTRDLEVAYNNLLRDKSALEEEKRQLEQENKDLARRLEGSSQEVARLRRGQCPSTHHPSQDMLPGSREVSQWNLDTLAFQELKSELTEVPASQILKNQSGHPRSKEGDKGCGVLMWVGEPVTLRTAETITGKYGVWMRDPKPTHPYTQETTWRIDTVGTGIRQVFEYSQISQFEQGYPSKVHVLPQALESTGAVVYSGSLYFQGAESRTVLRYELNTETVKAEKEIPGAGYHGQFPYAWGGYTDIDLAVDESGLWVIYSTEETRGAIVLSKLNPENLELESTWETNIRKQSVANAFVICGILYTVSSYSSVHATINFAYDTNTGISKTLTIPFKNRYKYSSMVDYNPLERKLFAWDNFNMVTYDIKLSEM", "length": 502 }, "evidence": [ { "id": "HGNC:7610", "url": "https://alliancegenome.org/gene/HGNC:7610#orthology", "database": "AGR" }, { "id": "RGD:620430", "url": "https://alliancegenome.org/gene/RGD:620430#orthology", "database": "AGR" }, { "id": "FB:FBgn0030887", "url": "https://alliancegenome.org/gene/FB:FBgn0030887#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VWZ7", "url": "https://www.uniprot.org/uniprotkb/Q9VWZ7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VWZ7", "url": "https://www.uniprot.org/uniprotkb/Q9VWZ7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "Q9VWZ7", "url": "https://www.uniprot.org/uniprotkb/Q9VWZ7" } ], "pmid": "" }, { "name": "motor neuron axon guidance", "id": "GO:0008045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008045", "evidence": [ { "database": "UniProtKB", "id": "Q9VWZ7", "url": "https://www.uniprot.org/uniprotkb/Q9VWZ7" } ], "pmid": "" }, { "name": "synaptic target inhibition", "id": "GO:0016201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016201", "evidence": [ { "database": "UniProtKB", "id": "Q9VWZ7", "url": "https://www.uniprot.org/uniprotkb/Q9VWZ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 106, "end_pos": 108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 11, "end_pos": 13, "annotation": "n_glycosylation_sequon" }, { "start_pos": 420, "end_pos": 422, "annotation": "n_glycosylation_sequon" }, { "start_pos": 454, "end_pos": 456, "annotation": "n_glycosylation_sequon" }, { "start_pos": 496, "end_pos": 498, "annotation": "n_glycosylation_sequon" }, { "start_pos": 518, "end_pos": 520, "annotation": "n_glycosylation_sequon" }, { "start_pos": 614, "end_pos": 616, "annotation": "n_glycosylation_sequon" }, { "start_pos": 679, "end_pos": 681, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" }, { "start_pos": 771, "end_pos": 773, "annotation": "n_glycosylation_sequon" }, { "start_pos": 837, "end_pos": 839, "annotation": "n_glycosylation_sequon" }, { "start_pos": 856, "end_pos": 858, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VWZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWZ7" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 431, "end_pos": 520, "start_aa": "Pro", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q9VWZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VWZ7" }, { "id": "PS51132", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51132" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Olfactomedin-like", "eco_id": "ECO_0000259", "start_pos": 691, "end_pos": 941, "start_aa": "Thr", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 106, "end_pos": 108 }, { "start_pos": 11, "end_pos": 13 }, { "start_pos": 420, "end_pos": 422 }, { "start_pos": 454, "end_pos": 456 }, { "start_pos": 496, "end_pos": 498 }, { "start_pos": 518, "end_pos": 520 }, { "start_pos": 614, "end_pos": 616 }, { "start_pos": 679, "end_pos": 681 }, { "start_pos": 6, "end_pos": 8 }, { "start_pos": 771, "end_pos": 773 }, { "start_pos": 837, "end_pos": 839 }, { "start_pos": 856, "end_pos": 858 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VX12-1", "uniprot_ac": "Q9VX12", "uniprot_id": "SPT7_DROME", "mass": { "chemical_mass": 39460.0, "monoisotopic_mass": 39460.0 }, "refseq": { "ac": "NP_573248", "name": "Spt7", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573248" }, "gene_names": [ { "name": "Spt7", "type": "recommended", "evidence": [ { "id": "Q9VX12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VX12" } ] }, { "name": "CG6506", "type": "synonym", "evidence": [ { "id": "NP_573248", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573248" }, { "id": "Q9VX12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VX12" } ] }, { "name": "Dmel\\CG6506", "type": "synonym", "evidence": [ { "id": "NP_573248", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573248" } ] }, { "name": "Spt7", "type": "synonym", "evidence": [ { "id": "NP_573248", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573248" } ] }, { "name": "cg6506", "type": "synonym", "evidence": [ { "id": "NP_573248", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573248" } ] }, { "name": "dSpt7", "type": "synonym", "evidence": [ { "id": "NP_573248", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573248" } ] } ], "protein_names": [ { "name": "SAGA complex subunit Spt7", "type": "recommended", "evidence": [ { "id": "Q9VX12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VX12/entry#names_and_taxonomy" } ] }, { "name": "CG6506-PA", "type": "synonym", "evidence": [ { "id": "NP_573248", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573248" } ] }, { "name": "Spt7-PA", "type": "synonym", "evidence": [ { "id": "NP_573248", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573248" } ] }, { "name": "Spt7", "type": "synonym", "evidence": [ { "id": "NP_573248", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573248" } ] } ], "function": [ { "annotation": "Component of the transcription regulatory complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination (PubMed:16980620, PubMed:20008933, PubMed:21764853, PubMed:24493646, PubMed:30559249). The SAGA complex predominantly acetylates histone H3 (PubMed:30559249).", "evidence": [ { "database": "UniProtKB", "id": "Q9VX12", "url": "https://www.uniprot.org/uniprotkb/Q9VX12#function" }, { "database": "PubMed", "id": "16980620", "url": "https://glygen.org/publication/PubMed/16980620" }, { "database": "PubMed", "id": "30559249", "url": "https://glygen.org/publication/PubMed/30559249" }, { "database": "PubMed", "id": "24493646", "url": "https://glygen.org/publication/PubMed/24493646" }, { "database": "PubMed", "id": "21764853", "url": "https://glygen.org/publication/PubMed/21764853" }, { "database": "PubMed", "id": "20008933", "url": "https://glygen.org/publication/PubMed/20008933" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VX12", "url": "https://www.uniprot.org/uniprotkb/Q9VX12" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Spt7", "url": "https://www.uniprot.org/uniprotkb/Q9VX12", "locus": { "chromosome": "X", "start_pos": 17851889, "end_pos": 17850460, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0030874", "url": "https://www.ensemblgenomes.org/id/FBgn0030874" } ] } } ], "crossref": [ { "id": "FB:FBgn0030874", "url": "https://alliancegenome.org/gene/FB:FBgn0030874", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "Q9VX12", "url": "https://alphafold.ebi.ac.uk/entry/Q9VX12", "database": "AlphaFoldDB", "categories": [] }, { "id": "FBgn0030874", "url": "https://bgee.org/?page=gene&gene_id=FBgn0030874", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06847", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06847", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0030874", "url": "https://flybase.org/reports/FBgn0030874", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "32766", "url": "https://www.ncbi.nlm.nih.gov/gene/32766", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VX12", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VX12*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR009072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039460", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039460", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG6506", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG6506", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FQKPIWF", "url": "https://omabrowser.org/oma/group/FQKPIWF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VX12", "url": "https://www.orthodb.org/?gene=Q9VX12", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28598", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28598", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28598:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28598:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PR:Q9VX12", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q9VX12", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_573248", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573248", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VX12", "url": "https://www.uniprot.org/uniprotkb/Q9VX12", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VX12-1", "url": "https://www.uniprot.org/uniprotkb/Q9VX12-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQTEHWGSLPAEDDGGQLTPDKYVPTAAKKLKLDEIRQRGDPQPQEKHHKLELRSALVTQTIEVMKQTEVLQSLIETYSNKNGSSNYLLNPCLMIPEVDFPPENAAELVGSQKFQKPIWFTPTVDTAYSRGDPEAYPEIPSSACRQAMRKVMCGMLRLAGFTDCSESAVQLLTDATEEFLRSFIGEYRGYYDSQPRLQNSTVLQLVPLERAHFAQTGTSLTQVHNYYKHKVLARNRAEIAEFNSVLQEYDKLMKESQSSMQKQHNEFNGHDFLNILDNSATGSSQSIGGMAMGDMLQDLGGSTGSSGTVSSQQMLYGLLDGQISSNTSNMTGTSGNGSTGGNGNGNGATISNFHATFET", "length": 359, "header": "sp|Q9VX12-1|SPT7_DROME Isoform 1 of SAGA complex subunit Spt7 OS=Drosophila melanogaster OX=7227 GN=Spt7 PE=1 SV=3 CANONICAL=Q9VX12-1" }, "isoforms": [ { "isoform_ac": "Q9VX12-1", "url": "https://www.uniprot.org/uniprotkb/Q9VX12/entry#Q9VX12-1", "sequence": { "sequence": "MQTEHWGSLPAEDDGGQLTPDKYVPTAAKKLKLDEIRQRGDPQPQEKHHKLELRSALVTQTIEVMKQTEVLQSLIETYSNKNGSSNYLLNPCLMIPEVDFPPENAAELVGSQKFQKPIWFTPTVDTAYSRGDPEAYPEIPSSACRQAMRKVMCGMLRLAGFTDCSESAVQLLTDATEEFLRSFIGEYRGYYDSQPRLQNSTVLQLVPLERAHFAQTGTSLTQVHNYYKHKVLARNRAEIAEFNSVLQEYDKLMKESQSSMQKQHNEFNGHDFLNILDNSATGSSQSIGGMAMGDMLQDLGGSTGSSGTVSSQQMLYGLLDGQISSNTSNMTGTSGNGSTGGNGNGNGATISNFHATFET", "length": 359, "header": "sp|Q9VX12-1|SPT7_DROME Isoform 1 of SAGA complex subunit Spt7 OS=Drosophila melanogaster OX=7227 GN=Spt7 PE=1 SV=3 CANONICAL=Q9VX12-1" }, "locus": { "chromosome": "X", "start_pos": 17850460, "end_pos": 17851889, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0074465", "url": "https://www.ensemblgenomes.org/id/FBtr0074465" }, { "database": "Ensembl Peptide", "id": "FBpp0074239", "url": "https://www.ensemblgenomes.org/id/FBpp0074239" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VX12", "url": "https://www.uniprot.org/uniprotkb/Q9VX12" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "A Drosophila full-length cDNA resource.", "journal": "Genome Biol.", "date": "2002", "authors": "Stapleton M, Carlson J, Brokstein P, Yu C, Champe M, George R, Guarin H, Kronmiller B, Pacleb J, Park S, Wan K, Rubin GM, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VX12", "url": "https://www.uniprot.org/uniprotkb/Q9VX12" } ], "reference": [ { "type": "PubMed", "id": "12537569", "url": "https://glygen.org/publication/PubMed/12537569" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VX12", "url": "https://www.uniprot.org/uniprotkb/Q9VX12" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The essential gene wda encodes a WD40 repeat subunit of Drosophila SAGA required for histone H3 acetylation.", "journal": "Molecular and cellular biology", "date": "2006-10", "authors": "Guelman Sebasti\u00e1n, Suganuma Tamaki, Florens Laurence, Weake Vikki, Swanson Selene K, Washburn Michael P, Abmayr Susan M, Workman Jerry L", "evidence": [ { "database": "UniProtKB", "id": "Q9VX12", "url": "https://www.uniprot.org/uniprotkb/Q9VX12" } ], "reference": [ { "type": "PubMed", "id": "16980620", "url": "https://glygen.org/publication/PubMed/16980620" } ] }, { "title": "A novel histone fold domain-containing protein that replaces TAF6 in Drosophila SAGA is required for SAGA-dependent gene expression.", "journal": "Genes & development", "date": "2009-12-15", "authors": "Weake Vikki M, Swanson Selene K, Mushegian Arcady, Florens Laurence, Washburn Michael P, Abmayr Susan M, Workman Jerry L", "evidence": [ { "database": "UniProtKB", "id": "Q9VX12", "url": "https://www.uniprot.org/uniprotkb/Q9VX12" } ], "reference": [ { "type": "PubMed", "id": "20008933", "url": "https://glygen.org/publication/PubMed/20008933" } ] }, { "title": "Post-transcription initiation function of the ubiquitous SAGA complex in tissue-specific gene activation.", "journal": "Genes & development", "date": "2011-07-15", "authors": "Weake Vikki M, Dyer Jamie O, Seidel Christopher, Box Andrew, Swanson Selene K, Peak Allison, Florens Laurence, Washburn Michael P, Abmayr Susan M, Workman Jerry L", "evidence": [ { "database": "UniProtKB", "id": "Q9VX12", "url": "https://www.uniprot.org/uniprotkb/Q9VX12" } ], "reference": [ { "type": "PubMed", "id": "21764853", "url": "https://glygen.org/publication/PubMed/21764853" } ] }, { "title": "Loss of Drosophila Ataxin-7, a SAGA subunit, reduces H2B ubiquitination and leads to neural and retinal degeneration.", "journal": "Genes & development", "date": "2014-02-01", "authors": "Mohan Ryan D, Dialynas George, Weake Vikki M, Liu Jianqi, Martin-Brown Skylar, Florens Laurence, Washburn Michael P, Workman Jerry L, Abmayr Susan M", "evidence": [ { "database": "UniProtKB", "id": "Q9VX12", "url": "https://www.uniprot.org/uniprotkb/Q9VX12" } ], "reference": [ { "type": "PubMed", "id": "24493646", "url": "https://glygen.org/publication/PubMed/24493646" } ] }, { "title": "The Drosophila Dbf4 ortholog Chiffon forms a complex with Gcn5 that is necessary for histone acetylation and viability.", "journal": "Journal of cell science", "date": "2019-01-16", "authors": "Torres-Zelada Eliana F, Stephenson Robert E, Alpsoy Aktan, Anderson Benjamin D, Swanson Selene K, Florens Laurence, Dykhuizen Emily C, Washburn Michael P, Weake Vikki M", "evidence": [ { "database": "UniProtKB", "id": "Q9VX12", "url": "https://www.uniprot.org/uniprotkb/Q9VX12" } ], "reference": [ { "type": "PubMed", "id": "30559249", "url": "https://glygen.org/publication/PubMed/30559249" } ] } ], "pathway": [ { "id": "dme:Dmel_CG6506", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG6506", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "O94864-1", "protein_name": "STAGA complex 65 subunit gamma", "gene_name": "SUPT7L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNLQRYWGEIPISSSQTNRSSFDLLPREFRLVEVHDPPLHQPSANKPKPPTMLDIPSEPCSLTIHTIQLIQHNRRLRNLIATAQAQNQQQTEGVKTEESEPLPSCPGSPPLPDDLLPLDCKNPNAPFQIRHSDPESDFYRGKGEPVTELSWHSCRQLLYQAVATILAHAGFDCANESVLETLTDVAHEYCLKFTKLLRFAVDREARLGQTPFPDVMEQVFHEVGIGSVLSLQKFWQHRIKDYHSYMLQISKQLSEEYERIVNPEKATEDAKPVKIKEEPVSDITFPVSEELEADLASGDQSLPMGVLGAQSERFPSNLEVEASPQASSAEVNASPLWNLAHVKMEPQESEEGNVSGHGVLGSDVFEEPMSGMSEAGIPQSPDDSDSSYGSHSTDSLMGSSPVFNQRCKKRMRKI", "length": 414 }, "evidence": [ { "id": "MGI:1919445", "url": "https://alliancegenome.org/gene/MGI:1919445#orthology", "database": "AGR" }, { "id": "HGNC:30632", "url": "https://alliancegenome.org/gene/HGNC:30632#orthology", "database": "AGR" }, { "id": "FB:FBgn0030874", "url": "https://alliancegenome.org/gene/FB:FBgn0030874#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CZV5-1", "protein_name": "STAGA complex 65 subunit gamma", "gene_name": "Supt7l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLRYWGEIPIPSGQTNRSSFDLLPREFRLVEVHDPPLHQPSANKPKPPTMLDIPSEPCSLTIHTIQLIQHNRRLRSLIATAQTQSQQQTEGVKAEESEPLPSCPGSPPLPDDLQPLDCKNPNAPFQIRHSDPESDFYRGKGEPVTELSWHSCRQLLYQAVATILAHTGFECANESVLETLTDVAHEYCLKFTKLLRFAVDREALLGQTPFPDVMEQVFHEVGIGSVLSLQKFWQHRIKDYHTYMLQISKQLSEEYERIVNPEKATEDTKPVKIKEEPVSDITFPVSEELEADLASGDQSLPIGVLGAQSERFPSNLEVEASPQAPSAEVNASPLWNLAHVKMEPQESEEGNVSAHGVLGSDVFEEPMSGMSEAGLPQSPDDSDSSYGSHSTDSLMGSSPVFNQRCRKRMRKI", "length": 412 }, "evidence": [ { "id": "MGI:1919445", "url": "https://alliancegenome.org/gene/MGI:1919445#orthology", "database": "AGR" }, { "id": "HGNC:30632", "url": "https://alliancegenome.org/gene/HGNC:30632#orthology", "database": "AGR" }, { "id": "FB:FBgn0030874", "url": "https://alliancegenome.org/gene/FB:FBgn0030874#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transcription coactivator activity", "id": 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Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VX15", "url": "https://www.uniprot.org/uniprotkb/Q9VX15" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VX15", "url": "https://www.uniprot.org/uniprotkb/Q9VX15" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VX15", "url": "https://www.uniprot.org/uniprotkb/Q9VX15" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VX15", "url": "https://www.uniprot.org/uniprotkb/Q9VX15" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VX15", "url": "https://www.uniprot.org/uniprotkb/Q9VX15" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VX15", "url": "https://www.uniprot.org/uniprotkb/Q9VX15" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VX15", "url": "https://www.uniprot.org/uniprotkb/Q9VX15" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VX15", "url": "https://www.uniprot.org/uniprotkb/Q9VX15" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VX15", "url": "https://www.uniprot.org/uniprotkb/Q9VX15" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VX15", "url": "https://www.uniprot.org/uniprotkb/Q9VX15" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VX15", "url": "https://www.uniprot.org/uniprotkb/Q9VX15" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], 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replication", "id": "GO:0006261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006261", "evidence": [ { "database": "UniProtKB", "id": "Q9VX15", "url": "https://www.uniprot.org/uniprotkb/Q9VX15" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q9VX15", "url": "https://www.uniprot.org/uniprotkb/Q9VX15" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VX15", "url": "https://www.uniprot.org/uniprotkb/Q9VX15" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "Q9VX15", "url": "https://www.uniprot.org/uniprotkb/Q9VX15" } ], "pmid": "" } ] }, { "name": "Cellular 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"end_pos": 118 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VX49-1", "uniprot_ac": "Q9VX49", "uniprot_id": "Q9VX49_DROME", "mass": { "chemical_mass": 84990.0, "monoisotopic_mass": 84990.0 }, "refseq": { "ac": "NP_573217", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573217" }, "gene_names": [ { "name": "Dmel\\CG8568", "type": "recommended", "evidence": [ { "id": "Q9VX49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VX49" } ] }, { "name": "CG8568", "type": "synonym", "evidence": [ { "id": "NP_573217", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573217" }, { "id": "Q9VX49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VX49" } ] }, { "name": "Dmel\\CG8568", "type": "synonym", "evidence": [ { "id": "NP_573217", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573217" } ] }, { "name": "Dmel_CG8568", "type": "synonym", "evidence": [ { "id": "Q9VX49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VX49" } ] } ], "protein_names": [ { "name": "DUF4773 domain-containing protein", "type": "recommended", "evidence": [ { "id": "Q9VX49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VX49/entry#names_and_taxonomy" } ] }, { "name": "CG8568-PA", "type": "synonym", "evidence": [ { "id": "NP_573217", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573217" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_573217", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573217" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VX49", "url": "https://www.uniprot.org/uniprotkb/Q9VX49" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG8568", "url": "https://www.uniprot.org/uniprotkb/Q9VX49", "locus": { "chromosome": "X", "start_pos": 17448990, "end_pos": 17452543, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0030841", "url": "https://www.ensemblgenomes.org/id/FBgn0030841" } ] } } ], "crossref": [ { "id": "FB:FBgn0030841", "url": "https://alliancegenome.org/gene/FB:FBgn0030841", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0030841", "url": "https://bgee.org/?page=gene&gene_id=FBgn0030841", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0030841", "url": "https://flybase.org/reports/FBgn0030841", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "32728", "url": "https://www.ncbi.nlm.nih.gov/gene/32728", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR031941", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031941", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG8568", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG8568", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EYPYQED", "url": "https://omabrowser.org/oma/group/EYPYQED/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VX49", "url": "https://www.orthodb.org/?gene=Q9VX49", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR36299", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR36299", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR36299:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR36299:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15998", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15998", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_573217", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573217", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VX49", "url": "https://www.uniprot.org/uniprotkb/Q9VX49", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VX49-1", "url": "https://www.uniprot.org/uniprotkb/Q9VX49-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIPWICLSAAIVLILCPLHTSSRSYSNGLIFYELKTHRPYLPPTVSVSRGRNLASVKYSEKGSIWSTFGQPCECSGPTCGCCAGLKVDQYRFDQKVCANVSFVPHLEEAQLEVFLNGRPSSKYGISVRNPAPFCIPVMMGVPMAMCVQMTDVTVVGNNLNMCMDFVVRMATTDLFEMHFQCMRMGLDGLQYVDKNGKPVLPMGDGQSDDPEEYEYAELEDQPEEYPYQEDVKEEAPSQGYQPDNNQQQKNTTLTTDQVKEDEMEKNQSMGYQPLIINNQAQKIEPQLNLEELIYQPQKNQTLSEPAKQDQVDKEEDTQNEESGYQTLGQIKVEDQKEEKPAEKQPEIQQPSENTLDEDEPMGYQPPMAMVPQKVPEEQPLAEDLQEEEEKTLESEGDHQEDEELEDVEPLPIESEMLMASDQAEEAPFEEEAEEMPAEDAKETAAEAAEKEKETGTESEQETPDNDNGYGESGLRPSQVIETITNSIKATEAPTTTTTTATITKIPTTTTKIPTTATTFNKPNIVIDGTNNGEKTVEAEGEKTVEEPEKEGETSEEGEAEDDEEDSTTVAVEMENDSDNEINVDDDDEVEKKNRVKEPPSQVKKEEKKQEEGAEEKSEEGVQKEEIEPEKEVKASHEEKVNPNDTAAEEDEDNEEEEDGEDEEGEEDEDDEEEEDEEDDEKEEGEVDAAEESAEAAKPEESAVKIDENGNGYENAYANANENASGNAYGNANATPAAKSLSRRRRLRTRRLPRPLRKHH", "length": 759, "header": "tr|Q9VX49-1|Q9VX49_DROME Isoform 1 of DUF4773 domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG8568 PE=4 SV=1 CANONICAL=Q9VX49-1" }, "isoforms": [ { "isoform_ac": "Q9VX49-1", "url": "https://www.uniprot.org/uniprotkb/Q9VX49/entry#Q9VX49-1", "sequence": { "sequence": "MIPWICLSAAIVLILCPLHTSSRSYSNGLIFYELKTHRPYLPPTVSVSRGRNLASVKYSEKGSIWSTFGQPCECSGPTCGCCAGLKVDQYRFDQKVCANVSFVPHLEEAQLEVFLNGRPSSKYGISVRNPAPFCIPVMMGVPMAMCVQMTDVTVVGNNLNMCMDFVVRMATTDLFEMHFQCMRMGLDGLQYVDKNGKPVLPMGDGQSDDPEEYEYAELEDQPEEYPYQEDVKEEAPSQGYQPDNNQQQKNTTLTTDQVKEDEMEKNQSMGYQPLIINNQAQKIEPQLNLEELIYQPQKNQTLSEPAKQDQVDKEEDTQNEESGYQTLGQIKVEDQKEEKPAEKQPEIQQPSENTLDEDEPMGYQPPMAMVPQKVPEEQPLAEDLQEEEEKTLESEGDHQEDEELEDVEPLPIESEMLMASDQAEEAPFEEEAEEMPAEDAKETAAEAAEKEKETGTESEQETPDNDNGYGESGLRPSQVIETITNSIKATEAPTTTTTTATITKIPTTTTKIPTTATTFNKPNIVIDGTNNGEKTVEAEGEKTVEEPEKEGETSEEGEAEDDEEDSTTVAVEMENDSDNEINVDDDDEVEKKNRVKEPPSQVKKEEKKQEEGAEEKSEEGVQKEEIEPEKEVKASHEEKVNPNDTAAEEDEDNEEEEDGEDEEGEEDEDDEEEEDEEDDEKEEGEVDAAEESAEAAKPEESAVKIDENGNGYENAYANANENASGNAYGNANATPAAKSLSRRRRLRTRRLPRPLRKHH", "length": 759, "header": "tr|Q9VX49-1|Q9VX49_DROME Isoform 1 of DUF4773 domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG8568 PE=4 SV=1 CANONICAL=Q9VX49-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 734, "start_aa": "Thr", "end_pos": 734, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr734", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 78, "start_aa": "Thr", "end_pos": 78, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr78", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VX49", "url": "https://www.uniprot.org/uniprotkb/Q9VX49" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VX49", "url": "https://www.uniprot.org/uniprotkb/Q9VX49" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin 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Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VX49", "url": "https://www.uniprot.org/uniprotkb/Q9VX49" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VX49", "url": "https://www.uniprot.org/uniprotkb/Q9VX49" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi 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"description": "" }, { "id": "DOID:1168", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1168", "name": "hyperlipemia", "description": "" } ], "unlinked_id_list": [ "DOID:0111417" ], "evidence": [ { "id": "1168", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1168" } ] }, { "disease_id": "DOID:1287", "recommended_name": { "id": "DOID:1287", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1287", "name": "cardiovascular system disease", "description": "A disease of anatomical entity which occurs in the blood, heart, blood vessels or the lymphatic system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells or lymph to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis." }, "synonyms": [ { "id": "DOID:1287", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1287", "name": "disease of subdivision of hemolymphoid system", "description": "" } ], "unlinked_id_list": [ "DOID:176", "DOID:0050826", "DOID:11840", "DOID:3527", "DOID:3316", "DOID:10314", "DOID:12326", "DOID:5749", "DOID:0060091", "DOID:4193", "DOID:864", "DOID:5238", "DOID:60006", "DOID:175", "DOID:235", "DOID:471", "DOID:0050829", "DOID:9768", "DOID:2348", "DOID:13089", "DOID:0060051", "DOID:5805", "DOID:13731", "DOID:0050825", "DOID:60001", "DOID:866", "DOID:2462", "DOID:60007", "DOID:272", "DOID:9742", "DOID:1729", "DOID:0050828", "DOID:11130", "DOID:1271", "DOID:3850", "DOID:0060228" ], "evidence": [ { "id": "1287", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1287" } ] }, { "disease_id": "DOID:1312", "recommended_name": { "id": "DOID:1312", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1312", "name": "focal segmental glomerulosclerosis", "description": "" }, "synonyms": [ { "id": "DOID:1312", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1312", "name": "FGS", "description": "" }, { "id": "DOID:1312", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1312", "name": "FSGS", "description": "" }, { "id": "DOID:1312", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1312", "name": "focal glomerular sclerosis", "description": "" }, { "id": "DOID:1312", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1312", "name": "focal glomerulosclerosis", "description": "" }, { "id": "MONDO:0011303", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011303", "name": "focal segmental glomerulosclerosis 1", "description": "Any focal segmental glomerulosclerosis in which the cause of the disease is a mutation in the ACTN4 gene." }, { "id": "MONDO:0011303", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011303", "name": "ACTN4 focal segmental glomerulosclerosis", "description": "" }, { "id": "MONDO:0011303", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011303", "name": "FSGS1", "description": "" }, { "id": "MONDO:0011303", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011303", "name": "familial idiopathic steroid-resistant nephrotic syndrome with focal segmental glomerulosclerosis", "description": "" }, { "id": "MONDO:0011303", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011303", "name": "focal segmental glomerulosclerosis 1", "description": "" }, { "id": "MONDO:0011303", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011303", "name": "focal segmental glomerulosclerosis caused by mutation in ACTN4", "description": "" }, { "id": "MONDO:0011303", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011303", "name": "focal segmental glomerulosclerosis type 1", "description": "" }, { "id": "MIM:603278", "resource": "MIM", "url": "https://www.omim.org/entry/603278", "name": "Focal segmental glomerulosclerosis 1", "description": "Focal segmental glomerulosclerosis 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "1312", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1312" } ] }, { "disease_id": "DOID:13809", "recommended_name": { "id": "DOID:13809", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13809", "name": "familial combined hyperlipidemia", "description": "" }, "synonyms": [ { "id": "DOID:13809", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13809", "name": "familial multiple lipoprotein-type hyperlipidemia", "description": "" }, { "id": "DOID:13809", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13809", "name": "mixed hyperlipidaemia", "description": "" }, { "id": "DOID:13809", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13809", "name": "type IIb hyperlipoproteinemia", "description": "" }, { "id": "DOID:13809", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13809", "name": "hyperbetalipoproteinemia with prebetalipoproteinemia", "description": "" }, { "id": "MONDO:0007759", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007759", "name": "hyperlipidemia, familial combined, LPL related", "description": "" }, { "id": "MONDO:0007759", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007759", "name": "combined hyperlipidemia, familial", "description": "" }, { "id": "MONDO:0007759", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007759", "name": "FCHL", "description": "" }, { "id": "MONDO:0007759", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007759", "name": "hyperlipidemia, familial combined", "description": "" }, { "id": "MIM:144250", "resource": "MIM", "url": "https://www.omim.org/entry/144250", "name": "Hyperlipidemia, familial combined, 3", "description": "Hyperlipidemia, familial combined, 3" } ], "unlinked_id_list": [], "evidence": [ { "id": "13809", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13809" } ] }, { "disease_id": "DOID:14118", "recommended_name": { "id": "DOID:14118", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14118", "name": "familial lipoprotein lipase deficiency", "description": "A familial hyperlipemia characterized by a deficiency of the enzyme lipoprotein lipase and the subsequent build up of chylomicrons and increased plasma concentration of triglycerides." }, "synonyms": [ { "id": "DOID:14118", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14118", "name": "Fredrickson type I hyperlipoproteinemia", "description": "" }, { "id": "DOID:14118", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14118", "name": "Fredrickson type I lipaemia", "description": "" }, { "id": "DOID:14118", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14118", "name": "familial LPL deficiency", "description": "" }, { "id": "DOID:14118", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14118", "name": "familial hyperlipoproteinemia type I", "description": "" }, { "id": "DOID:14118", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14118", "name": "hypercholesterinaemic xanthomatosis", "description": "" }, { "id": "DOID:14118", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14118", "name": "hyperchylomicronemia", "description": "" }, { "id": "DOID:14118", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14118", "name": "mixed hyperglyceridemia", "description": "" }, { "id": "MONDO:0009387", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009387", "name": "familial lipoprotein lipase deficiency", "description": "Familial lipoprotein lipase deficiency is a rare genetic disorder is which a person lacks the enzyme lipoprotein lipase, a protein needed to break down fat molecules. Deficiency of this enzyme prevents affected individuals from properly digesting certain fats. This results in the accumulation of fatty droplets called chylomicrons in the blood and an increase in the blood concentration of triglycerides. Symptoms include episodes of abdominal pain, recurrent inflammation of the pancreas (pancreatitis), abnormal enlargement of the liver and/or spleen (hepatosplenomegaly), and the development of skin lesions known as erruptive xanthomas. Familial lipoprotein lipase deficiency is caused by changes (mutations) in the LPL gene. It is inherited in an autosomal recessive pattern. Treatment aims to control symptoms and blood triglyceride levels with a very low-fat diet. Treatment for individual symptoms (i.e. pancreatitis) involves following established treatment guidelines." }, { "id": "MONDO:0009387", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009387", "name": "familial chylomicronemia syndrome", "description": "" }, { "id": "MONDO:0009387", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009387", "name": "hyperlipoproteinemia type I", "description": "" }, { "id": "MONDO:0009387", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009387", "name": "hyperlipoproteinemia, type 1", "description": "" }, { "id": "MONDO:0009387", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009387", "name": "hyperlipoproteinemia, type I", "description": "" }, { "id": "MONDO:0009387", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009387", "name": "type I hyperlipoproteinemia", "description": "" }, { "id": "MONDO:0009387", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009387", "name": "LPL deficiency", "description": "" }, { "id": "MONDO:0009387", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009387", "name": "familial lipoprotein lipase deficiency (disorder) [ambiguous]", "description": "" }, { "id": "MONDO:0009387", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009387", "name": "familial lipoprotein lipase deficiency with type I phenotype", "description": "" }, { "id": "MONDO:0009387", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009387", "name": "high density lipoprotein cholesterol level QTL 11", "description": "" }, { "id": "MONDO:0009387", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009387", "name": "hyperchylomicronemia", "description": "" }, { "id": "MONDO:0009387", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009387", "name": "Burger-Grutz syndrome", "description": "" }, { "id": "MONDO:0009387", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009387", "name": "endogenous hypertriglyceridaemia", "description": "" }, { "id": "MONDO:0009387", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009387", "name": "familial fat-induced hypertriglyceridemia", "description": "" }, { "id": "MONDO:0009387", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009387", "name": "familial hyperchylomicronemia", "description": "" }, { "id": "MONDO:0009387", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009387", "name": "lipoprotein lipase deficiency, familial", "description": "" }, { "id": "MIM:238600", "resource": "MIM", "url": "https://www.omim.org/entry/238600", "name": "Hyperlipoproteinemia 1", "description": "Hyperlipoproteinemia 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "14118", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14118" } ] }, { "disease_id": "DOID:14221", "recommended_name": { "id": "DOID:14221", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14221", "name": "abdominal obesity-metabolic syndrome 1", "description": "An abdominal obesity-metabolic syndrome characterized by insulin resistance and hyperinsulinemia, dyslipidemia, essential hypertension, abdominal obesity, glucose intolerance or noninsulin-dependent diabetes mellitus and an increased risk of cardiovascular events." }, "synonyms": [ { "id": "DOID:14221", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14221", "name": "dysmetabolic syndrome X", "description": "" }, { "id": "DOID:14221", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14221", "name": "metabolic syndrome X", "description": "" }, { "id": "MONDO:0011565", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011565", "name": "metabolic syndrome X", "description": "" }, { "id": "MONDO:0011565", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011565", "name": "abdominal obesity-metabolic syndrome 1", "description": "" }, { "id": "MONDO:0011565", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011565", "name": "metabolic syndrome type X", "description": "" }, { "id": "MONDO:0011565", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011565", "name": "AOMS1", "description": "" }, { "id": "MONDO:0011565", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011565", "name": "abdominal obesity metabolic syndrome", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "14221", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14221" } ] }, { "disease_id": "DOID:2018", "recommended_name": { "id": "DOID:2018", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2018", "name": "hyperinsulinism", "description": "" }, "synonyms": [ { "id": "DOID:2018", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2018", "name": "hyperinsulinemia", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "2018", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2018" } ] }, { "disease_id": "DOID:3393", "recommended_name": { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "coronary artery disease", "description": "An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles." }, "synonyms": [ { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "CHD", "description": "" }, { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "Coronary disease", "description": "" }, { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "coronary arteriosclerosis", "description": "" }, { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "coronary heart disease", "description": "" }, { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "Ischemic Heart Disease", "description": "" }, { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "myocardial ischemia", "description": "" }, { "id": "MONDO:0010331", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010331", "name": "coronary heart disease, susceptibility to, 3", "description": "" }, { "id": "MONDO:0010331", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010331", "name": "coronary heart disease, susceptibility to, 3", "description": "" }, { "id": "MONDO:0010331", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010331", "name": "coronary heart disease, susceptibility to, type 3", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary heart disease, susceptibility to, 1", "description": "Any coronary artery disease in which the cause of the disease is a mutation in the CX3CR1 gene." }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "CX3CR1 coronary artery disease", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary artery disease caused by mutation in CX3CR1", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary artery disease, resistance to", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary heart disease, susceptibility to", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary heart disease, susceptibility to, 1", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary heart disease, susceptibility to, type 1", "description": "" }, { "id": "MONDO:0012009", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012009", "name": "coronary heart disease, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012009", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012009", "name": "coronary heart disease, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012009", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012009", "name": "coronary heart disease, susceptibility to, type 2", "description": "" }, { "id": "MONDO:0012010", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012010", "name": "coronary heart disease, susceptibility to, 4", "description": "" }, { "id": "MONDO:0012010", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012010", "name": "coronary heart disease, susceptibility to, 4", "description": "" }, { "id": "MONDO:0012010", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012010", "name": "coronary heart disease, susceptibility to, type 4", "description": "" }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "coronary artery disease, autosomal dominant, 1", "description": "Any coronary artery disease in which the cause of the disease is a mutation in the MEF2A gene." }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "MEF2A coronary artery disease", "description": "" }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "coronary artery disease caused by mutation in MEF2A", "description": "" }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "coronary artery disease, autosomal dominant, 1", "description": "" }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "coronary artery disease, autosomal dominant, type 1", "description": "" }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "ADCAD1", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "coronary artery disease, autosomal dominant 2", "description": "Any coronary artery disease in which the cause of the disease is a mutation in the LRP6 gene." }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "LRP6 coronary artery disease", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "coronary artery disease caused by mutation in LRP6", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "coronary artery disease, autosomal dominant 2", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "coronary artery disease, autosomal dominant type 2", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "coronary artery disease, autosomal dominant, 2", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "ADCAD2", "description": "" }, { "id": "MONDO:0012628", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012628", "name": "coronary heart disease, susceptibility to, 8", "description": "" }, { "id": "MONDO:0012628", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012628", "name": "CHDS8", "description": "" }, { "id": "MONDO:0012628", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012628", "name": "coronary heart disease, susceptibility to, 8", "description": "" }, { "id": "MONDO:0012788", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012788", "name": "coronary heart disease, susceptibility to, 9", "description": "" }, { "id": "MONDO:0012788", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012788", "name": "CHDS9", "description": "" }, { "id": "MONDO:0012788", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012788", "name": "coronary heart disease, susceptibility to, 9", "description": "" }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "hydatidiform mole, recurrent, 2", "description": "Any complete hydatidiform mole in which the cause of the disease is a mutation in the KHDC3L gene." }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "KHDC3L complete hydatidiform mole", "description": "" }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "complete hydatidiform mole caused by mutation in KHDC3L", "description": "" }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "hydatidiform Mole, recurrent, type 2", "description": "" }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "hydatidiform mole, recurrent, 2", "description": "" }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "HYDM2", "description": "" }, { "id": "MIM:608320", "resource": "MIM", "url": "https://www.omim.org/entry/608320", "name": "Coronary artery disease, autosomal dominant, 1", "description": "Coronary artery disease, autosomal dominant, 1" }, { "id": "MIM:610947", "resource": "MIM", "url": "https://www.omim.org/entry/610947", "name": "Coronary artery disease, autosomal dominant, 2", "description": "Coronary artery disease, autosomal dominant, 2" }, { "id": "MIM:614293", "resource": "MIM", "url": "https://www.omim.org/entry/614293", "name": "Hydatidiform mole, recurrent, 2", "description": "Hydatidiform mole, recurrent, 2" } ], "unlinked_id_list": [ "DOID:11840" ], "evidence": [ { "id": "3393", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3393" } ] }, { "disease_id": "DOID:341", "recommended_name": { "id": "DOID:341", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:341", "name": "peripheral vascular disease", "description": "A vascular disease that is characterized by obstruction of vessels not within the coronary, aortic arch vasculature, or brain." }, "synonyms": [ { "id": "DOID:341", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:341", "name": "arterial occlusive disease", "description": "" } ], "unlinked_id_list": [ "DOID:1729" ], "evidence": [ { "id": "341", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:341" } ] }, { "disease_id": "DOID:3526", "recommended_name": { "id": "DOID:3526", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3526", "name": "cerebral infarction", "description": "A cerebrovascular disease that is characterized by an area of necrotic tissue in the brain resulting from a blockage or narrowing in the arteries supplying blood and oxygen to the brain." }, "synonyms": [ { "id": "DOID:3526", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3526", "name": "Cerebral infarct", "description": "" }, { "id": "MONDO:0020671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0020671", "name": "obsolete susceptibility to ischemic stroke", "description": "" }, { "id": "MONDO:0020671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0020671", "name": "cerebral infarction, susceptibility to", "description": "" }, { "id": "MONDO:0020671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0020671", "name": "ischemic stroke, susceptibility to", "description": "" }, { "id": "MONDO:0020671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0020671", "name": "stroke, ischemic, susceptibility to", "description": "" }, { "id": "MONDO:0020671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0020671", "name": "stroke, susceptibility to", "description": "" }, { "id": "MIM:601367", "resource": "MIM", "url": "https://www.omim.org/entry/601367", "name": "Ischemic stroke", "description": "Ischemic stroke" } ], "unlinked_id_list": [], "evidence": [ { "id": "3526", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3526" } ] }, { "disease_id": "DOID:557", "recommended_name": { "id": "DOID:557", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:557", "name": "kidney disease", "description": "A urinary system disease that is located_in the kidney." }, "synonyms": [ { "id": "DOID:557", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:557", "name": "nephropathy", "description": "" }, { "id": "DOID:557", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:557", "name": "impaired renal function disease", "description": "" } ], "unlinked_id_list": [ "DOID:0081055", "DOID:3116", "DOID:13138", "DOID:3675", "DOID:4455", "DOID:0080616", "DOID:2744", "DOID:9808", "DOID:582" ], "evidence": [ { "id": "557", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:557" } ] }, { "disease_id": "DOID:5844", "recommended_name": { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia." }, "synonyms": [ { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "Myocardial infarct", "description": "" }, { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "heart attack", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, type 2", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ] }, { "disease_id": "DOID:783", "recommended_name": { "id": "DOID:783", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:783", "name": "end stage renal disease", "description": "A chronic kidney disease is characterized by non-functioning kidneys, as the final stage in chronic kidney disease." }, "synonyms": [ { "id": "DOID:783", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:783", "name": "end stage renal failure", "description": "" }, { "id": "DOID:783", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:783", "name": "end-stage kidney disease", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "783", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:783" } ] }, { "disease_id": "DOID:9352", "recommended_name": { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin." }, "synonyms": [ { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "NIDDM", "description": "" }, { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "non-insulin-dependent diabetes mellitus", "description": "" }, { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "type 2 diabetes", "description": "" }, { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "type II diabetes mellitus", "description": "" }, { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "insulin resistance", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type 2 diabetes mellitus", "description": "A type of diabetes mellitus that is characterized by insulin resistance or desensitization and increased blood glucose levels. This is a chronic disease that can develop gradually over the life of a patient and can be linked to both environmental factors and heredity." }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "NIDDM", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "T2D", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "T2DM", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "T2DM - type 2 diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "adult onset diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "adult-onset diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitis type 2", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitis type II", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent, association with", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent, late onset", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, type 2", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, type II", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes, type 2", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "insulin resistance, severe, digenic", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "non-insulin dependent diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "non-insulin dependent diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "noninsulin dependent diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "noninsulin-dependent diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type 2 diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type 2 diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type 2 diabetes mellitus non-insulin dependent", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type II diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type II diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent, 2", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "diabetes mellitus, noninsulin-dependent, 1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "diabetes mellitus, noninsulin-dependent 1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "diabetes mellitus, noninsulin-dependent, 1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "diabetes mellitus, noninsulin-dependent, type 1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "NIDDM1", "description": "" }, { "id": "MONDO:0011072", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011072", "name": "diabetes mellitus, noninsulin-dependent, 2", "description": "" }, { "id": "MONDO:0011072", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011072", "name": "NIDDM2", "description": "" }, { "id": "MONDO:0011072", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011072", "name": "diabetes mellitus, noninsulin-dependent, 2", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "diabetes mellitus, noninsulin-dependent, 3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "diabetes mellitus, noninsulin-dependent, 3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "diabetes mellitus, noninsulin-dependent, type 3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "type 2 diabetes mellitus 3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "NIDDM3", "description": "" }, { "id": "MONDO:0011955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011955", "name": "diabetes mellitus, noninsulin-dependent, 4", "description": "" }, { "id": "MONDO:0011955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011955", "name": "diabetes mellitus, noninsulin-dependent, 4", "description": "" }, { "id": "MONDO:0011955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011955", "name": "diabetes mellitus, noninsulin-dependent, type 4", "description": "" }, { "id": "MIM:125853", "resource": "MIM", "url": "https://www.omim.org/entry/125853", "name": "Type 2 diabetes mellitus", "description": "Type 2 diabetes mellitus" }, { "id": "MIM:601283", "resource": "MIM", "url": "https://www.omim.org/entry/601283", "name": "Type 2 diabetes mellitus 1", "description": "Type 2 diabetes mellitus 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ] }, { "disease_id": "DOID:9744", "recommended_name": { "id": "DOID:9744", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9744", "name": "type 1 diabetes mellitus", "description": "A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production." }, "synonyms": [ { "id": "DOID:9744", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9744", "name": "IDDM", "description": "" }, { "id": "DOID:9744", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9744", "name": "insulin-dependent diabetes mellitus", "description": "" }, { "id": "DOID:9744", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9744", "name": "type I diabetes mellitus", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "type 1 diabetes mellitus", "description": "A chronic condition characterized by minimal or absent production of insulin by the pancreas." }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "IDDM", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "T1D", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "T1DM", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "diabetes mellitis type 1", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "diabetes mellitis type I", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "immune mediated diabetes", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "insulin dependent diabetes", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "juvenile diabetes", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "type 1 diabetes", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "type I diabetes", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "type I diabetes mellitus", "description": "" }, { "id": "MIM:222100", "resource": "MIM", "url": "https://www.omim.org/entry/222100", "name": "Type 1 diabetes mellitus", "description": "Type 1 diabetes mellitus" } ], "unlinked_id_list": [], "evidence": [ { "id": "9744", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9744" } ] }, { "disease_id": "DOID:9970", "recommended_name": { "id": "DOID:9970", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness." }, "synonyms": [ { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "inherited obesity", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "genetic obesity", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "genetic obesity (disease)", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "leanness, inherited, autosomal recessive", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "monogenic obesity", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "obesity, association with, Autosomal recessive", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "obesity, early-onset, susceptibility to, Autosomal recessive", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "obesity, late-onset, Autosomal recessive", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "obesity, mild, early-onset, Autosomal recessive", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "obesity, severe, Autosomal recessive", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "obesity, severe, and type II diabetes, Autosomal recessive", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "obesity, susceptibility to, Autosomal recessive", "description": "" }, { "id": "MIM:601665", "resource": "MIM", "url": "https://www.omim.org/entry/601665", "name": "Obesity", "description": "Obesity" } ], "unlinked_id_list": [], "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VX69", "url": "https://www.uniprot.org/uniprotkb/Q9VX69" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG5162", "url": "https://www.uniprot.org/uniprotkb/Q9VX69", "locus": { "chromosome": "X", "start_pos": 17217365, "end_pos": 17215304, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0030828", "url": "https://www.ensemblgenomes.org/id/FBgn0030828" } ] } } ], "crossref": [ { "id": "FB:FBgn0030828", "url": "https://alliancegenome.org/gene/FB:FBgn0030828", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0030828", "url": "https://bgee.org/?page=gene&gene_id=FBgn0030828", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00707", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00707", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0030828", "url": "https://flybase.org/reports/FBgn0030828", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "32709", "url": "https://www.ncbi.nlm.nih.gov/gene/32709", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013818", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013818", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033906", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033906", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG5162", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG5162", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RDPMGDV", "url": "https://omabrowser.org/oma/group/RDPMGDV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VX69", "url": "https://www.orthodb.org/?gene=Q9VX69", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11610", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11610", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11610:SF149", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11610:SF149", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00151", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00151", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-192456", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-192456", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-8963889", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8963889", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-8964058", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8964058", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001285367", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285367", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VX69", "url": "https://www.uniprot.org/uniprotkb/Q9VX69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VX69-1", "url": "https://www.uniprot.org/uniprotkb/Q9VX69-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGRVPAKMHTLLALLLQLLVASIHAIEWSLPDVINSIGNVGTSIVDPSLLPTPQGLLEGSKQLIAGYPFEFVSNSLNVICSQALASNKIKSKYSPDINKMNFQLQTACEKKNFPLTSPESMWKSPLFDVKKKVVILATGWTTTVNGSDTIEVFSKAYNCRGDVNFVAVDAARFVDTLYTWSAFNTEEIGENIALGLVKLLDLVPVENIHLIGHSLGAHIVGSAGRHLQHLTNQTIPRITGLDPAKPCFNEGEALSGLMRGDAHFVDVIHSNPGVLGKRDPVGDVDFYPGGMSPLAAGCFSVTCAHARSWEYFAETVFPGNERNFMATRCNSISKLRDFRCPGDEVPMGYAVPQNIKGNYFLEVSASAPFGMHASVVRSAHLEHCGLCPESTSTTEVPSTTTTGKPGSWFSG", "length": 411, "header": "tr|Q9VX69-1|Q9VX69_DROME Isoform 1 of Lipase domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG5162 PE=1 SV=1 CANONICAL=Q9VX69-1" }, "isoforms": [ { "isoform_ac": "Q9VX69-1", "url": "https://www.uniprot.org/uniprotkb/Q9VX69/entry#Q9VX69-1", "sequence": { "sequence": "MGRVPAKMHTLLALLLQLLVASIHAIEWSLPDVINSIGNVGTSIVDPSLLPTPQGLLEGSKQLIAGYPFEFVSNSLNVICSQALASNKIKSKYSPDINKMNFQLQTACEKKNFPLTSPESMWKSPLFDVKKKVVILATGWTTTVNGSDTIEVFSKAYNCRGDVNFVAVDAARFVDTLYTWSAFNTEEIGENIALGLVKLLDLVPVENIHLIGHSLGAHIVGSAGRHLQHLTNQTIPRITGLDPAKPCFNEGEALSGLMRGDAHFVDVIHSNPGVLGKRDPVGDVDFYPGGMSPLAAGCFSVTCAHARSWEYFAETVFPGNERNFMATRCNSISKLRDFRCPGDEVPMGYAVPQNIKGNYFLEVSASAPFGMHASVVRSAHLEHCGLCPESTSTTEVPSTTTTGKPGSWFSG", "length": 411, "header": "tr|Q9VX69-1|Q9VX69_DROME Isoform 1 of Lipase domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG5162 PE=1 SV=1 CANONICAL=Q9VX69-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VX69", "url": "https://www.uniprot.org/uniprotkb/Q9VX69" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VX69", "url": "https://www.uniprot.org/uniprotkb/Q9VX69" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VX69", "url": "https://www.uniprot.org/uniprotkb/Q9VX69" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VX69", "url": "https://www.uniprot.org/uniprotkb/Q9VX69" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VX69", "url": "https://www.uniprot.org/uniprotkb/Q9VX69" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VX69", "url": "https://www.uniprot.org/uniprotkb/Q9VX69" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VX69", "url": "https://www.uniprot.org/uniprotkb/Q9VX69" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VX69", "url": "https://www.uniprot.org/uniprotkb/Q9VX69" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VX69", "url": "https://www.uniprot.org/uniprotkb/Q9VX69" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VX69", "url": "https://www.uniprot.org/uniprotkb/Q9VX69" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VX69", "url": "https://www.uniprot.org/uniprotkb/Q9VX69" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG5162", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG5162", "resource": "KEGG Pathway" }, { "id": "R-DME-192456", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-192456", "resource": "Reactome", "description": "Digestion of dietary lipid" }, { "id": "R-DME-8963889", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8963889", "resource": "Reactome", "description": "Assembly of active LPL and LIPC lipase complexes" }, { "id": "R-DME-8964058", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8964058", "resource": "Reactome", "description": "HDL remodeling" } ], "orthologs": [ { "uniprot_canonical_ac": "A8DYT7-1", "protein_name": "Lipase domain-containing protein", "gene_name": "CG9966", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSIYSTLILLLTIVSGFCKGENHTRGWLPEFCVVGEQKCPNSRVSFWLYTNQTRDDPIQLDPLNPQKDVFQPRLPLKILIHGFIGNRNLTPNLEVRDVLLQTQPINVISVDYGTLVRWPCYYPWAVNNAPIVSECLAQMINNLISAGISRREDIHLIGFSLGAQVAGMVANYVSQPLARITGLDPAGPGFMMQPSLQQKLDASDADFVDIIHTDPFFFSMLPPMGHADFYPNLDQLNQRGCSYISNWRFYNCNHYRAAVYYGESIISERGFWAQQCGGWFDFFSQRCSHYSNMPNTQMGYFVSEDASGSYFLTTHEVAPFAKGPLVEVEFDVSELRNFTEIELR", "length": 344 }, "evidence": [ { "id": "HGNC:6619", "url": "https://alliancegenome.org/gene/HGNC:6619#orthology", "database": "AGR" }, { "id": "HGNC:6623", "url": "https://alliancegenome.org/gene/HGNC:6623#orthology", "database": "AGR" }, { "id": "HGNC:6677", "url": "https://alliancegenome.org/gene/HGNC:6677#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "M9MRT1-1", "protein_name": "Lipase domain-containing protein", "gene_name": "chr2L_10724193_10724543.0", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDKMLTSLIALLLSLLSLNPITNASKYHREALQFLLRNGNFDLNPLNCHILLWETCPKRFIDYQLFTSNGPRRGTPLNVKNPITLYKGGFSKHRETVFIIHGFNGTAIDIHLQFLRDAYLSRDFNVITVDWRPLTRYPCYLHSLINTRLTAQCTAQIYAFLTHYGAVRERITCVGHSLGAHICGMISNHLTRKQYRIIGLDPARPLIERMKSNKFRLSIDDANVIQVLHTNAGFLGQEDNSGHLNYCVNGGRIQPFCKGNPIRKSRCSHFLSICYLATATFKHNKFMGVPCPNGCLNLSGSKRLPVSGKVNPFEFASLIREYHIGNDAPDDARGCICIDVPYAKHCPFTDA", "length": 351 }, "evidence": [ { "id": "HGNC:6619", "url": "https://alliancegenome.org/gene/HGNC:6619#orthology", "database": "AGR" }, { "id": "HGNC:6623", "url": "https://alliancegenome.org/gene/HGNC:6623#orthology", "database": "AGR" }, { "id": "HGNC:6677", "url": "https://alliancegenome.org/gene/HGNC:6677#orthology", "database": "AGR" }, { "id": "MGI:96820", "url": "https://alliancegenome.org/gene/MGI:96820#orthology", "database": "AGR" }, { "id": "RGD:1310740", "url": "https://alliancegenome.org/gene/RGD:1310740#orthology", "database": "AGR" }, { "id": "RGD:3017", "url": "https://alliancegenome.org/gene/RGD:3017#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "M9NFL7-1", "protein_name": "Lipase domain-containing protein", "gene_name": "cg5665", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRILCGIVILLRLGALGDIAVDEEGRLTRSWWDAVPRLLTDIATIKANILTAAPLELASNIIDAVCSSTLFMDRIPAQITPDIRKMHFQYMTPCQNYSVPLLEASKLWKHSRFSKGRKVVILATGWTNTVNESSAISMISKAFMCRGDVNFVIVDAADYVDTFYAWSALNTDLIGEHIGVGLTHLIELTPLRNIHLIGGFIKESFVSINSGSDFFVGHSLGAHIMGTAGRTFKKLTGKLIPRITGLDPAKPCFRREKILPGLTRGDAKLVDIIHTNIGILAKRGPLGDVDFYPGGAHPIQPGCLTIGCSHTRAVEYFAESAYPHQEKNFMGKKCASWDELRKRDCSAGIVSPMGYRMNPQARGIYYVDVNGWPPYGRNSENTVDPRLKTCYLCRR", "length": 395 }, "evidence": [ { "id": "HGNC:6619", "url": "https://alliancegenome.org/gene/HGNC:6619#orthology", "database": "AGR" }, { "id": "HGNC:6623", "url": "https://alliancegenome.org/gene/HGNC:6623#orthology", "database": "AGR" }, { "id": "HGNC:6677", "url": "https://alliancegenome.org/gene/HGNC:6677#orthology", "database": "AGR" }, { "id": "MGI:96820", "url": "https://alliancegenome.org/gene/MGI:96820#orthology", "database": "AGR" }, { "id": "RGD:1310740", "url": "https://alliancegenome.org/gene/RGD:1310740#orthology", "database": "AGR" }, { "id": "RGD:3017", "url": "https://alliancegenome.org/gene/RGD:3017#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P06858-1", "protein_name": "Lipoprotein lipase", "gene_name": "LPL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESKALLVLTLAVWLQSLTASRGGVAAADQRRDFIDIESKFALRTPEDTAEDTCHLIPGVAESVATCHFNHSSKTFMVIHGWTVTGMYESWVPKLVAALYKREPDSNVIVVDWLSRAQEHYPVSAGYTKLVGQDVARFINWMEEEFNYPLDNVHLLGYSLGAHAAGIAGSLTNKKVNRITGLDPAGPNFEYAEAPSRLSPDDADFVDVLHTFTRGSPGRSIGIQKPVGHVDIYPNGGTFQPGCNIGEAIRVIAERGLGDVDQLVKCSHERSIHLFIDSLLNEENPSKAYRCSSKEAFEKGLCLSCRKNRCNNLGYEINKVRAKRSSKMYLKTRSQMPYKVFHYQVKIHFSGTESETHTNQAFEISLYGTVAESENIPFTLPEVSTNKTYSFLIYTEVDIGELLMLKLKWKSDSYFSWSDWWSSPGFAIQKIRVKAGETQKKVIFCSREKVSHLQKGKAPAVFVKCHDKSLNKKSG", "length": 475 }, "evidence": [ { "id": "HGNC:6677", "url": "https://alliancegenome.org/gene/HGNC:6677#orthology", "database": "AGR" }, { "id": "MGI:96820", "url": "https://alliancegenome.org/gene/MGI:96820#orthology", "database": "AGR" }, { "id": "RGD:3017", "url": "https://alliancegenome.org/gene/RGD:3017#orthology", "database": "AGR" }, { "id": "FB:FBgn0030828", "url": "https://alliancegenome.org/gene/FB:FBgn0030828#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P07867-1", "protein_name": "Hepatic triacylglycerol lipase", "gene_name": "Lipc", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGNHLQISVSLVLCIFIQSSACGQGVGTEPFGRNLGATEERKPLQKPEIRFLLFKDESDRLGCQLRPQHPETLQECGFNSSHPLVMIIHGWSVDGLLETWIWKIVGALKSRQSQPVNVGLVDWISLAYQHYAIAVRNTRVVGQEVAALLLWLEESMKFSRSKVHLIGYSLGAHVSGFAGSSMGGKRKIGRITGLDPAGPMFEGTSPNERLSPDDANFVDAIHTFTREHMGLSVGIKQPIAHYDFYPNGGSFQPGCHFLELYKHIAEHGLNAITQTINCAHERSVHLFIDSLQHSNLQNTGFQCSNMDSFSQGLCLNCKKGRCNSLGYDIRRIGHVKSKTLFLITRAQSPFKVYHYQFKIQFINQMEKPMEPTFTMTLLGTKEEIKKIPITLGEGITSNKTYSLLITLNKDIGELIMLKFKWENSAVWANVWNTVQTIMLWDTEPHYAGLIVKTIWVKAGETQQRMTFCPDNVDDLQLHPTQEKVFVKCDLKSKD", "length": 494 }, "evidence": [ { "id": "HGNC:6619", "url": "https://alliancegenome.org/gene/HGNC:6619#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P11150-1", "protein_name": "Hepatic triacylglycerol lipase", "gene_name": "LIPC", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDTSPLCFSILLVLCIFIQSSALGQSLKPEPFGRRAQAVETNKTLHEMKTRFLLFGETNQGCQIRINHPDTLQECGFNSSLPLVMIIHGWSVDGVLENWIWQMVAALKSQPAQPVNVGLVDWITLAHDHYTIAVRNTRLVGKEVAALLRWLEESVQLSRSHVHLIGYSLGAHVSGFAGSSIGGTHKIGRITGLDAAGPLFEGSAPSNRLSPDDANFVDAIHTFTREHMGLSVGIKQPIGHYDFYPNGGSFQPGCHFLELYRHIAQHGFNAITQTIKCSHERSVHLFIDSLLHAGTQSMAYPCGDMNSFSQGLCLSCKKGRCNTLGYHVRQEPRSKSKRLFLVTRAQSPFKVYHYQFKIQFINQTETPIQTTFTMSLLGTKEKMQKIPITLGKGIASNKTYSFLITLDVDIGELIMIKFKWENSAVWANVWDTVQTIIPWSTGPRHSGLVLKTIRVKAGETQQRMTFCSENTDDLLLRPTQEKIFVKCEIKSKTSKRKIR", "length": 499 }, "evidence": [ { "id": "HGNC:6619", "url": "https://alliancegenome.org/gene/HGNC:6619#orthology", "database": "AGR" }, { "id": "FB:FBgn0030828", "url": "https://alliancegenome.org/gene/FB:FBgn0030828#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P11152-1", "protein_name": "Lipoprotein lipase", "gene_name": "Lpl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESKALLLVVLGVWLQSLTAFRGGVAAADAGRDFSDIESKFALRTPEDTAEDTCHLIPGLADSVSNCHFNHSSKTFVVIHGWTVTGMYESWVPKLVAALYKREPDSNVIVVDWLYRAQQHYPVSAGYTKLVGNDVARFINWMEEEFNYPLDNVHLLGYSLGAHAAGVAGSLTNKKVNRITGLDPAGPNFEYAEAPSRLSPDDADFVDVLHTFTRGSPGRSIGIQKPVGHVDIYPNGGTFQPGCNIGEAIRVIAERGLGDVDQLVKCSHERSIHLFIDSLLNEENPSKAYRCNSKEAFEKGLCLSCRKNRCNNLGYEINKVRAKRSSKMYLKTRSQMPYKVFHYQVKIHFSGTEDGKQHNQAFEISLYGTVAESENIPFTLPEVSTNKTYSFLIYTEVDIGELLMMKLKWISDSYFSWPDWWSSPSFVIERIRVKAGETQKKVIFCAREKVSHLQKGKDSAVFVKCHDKSLKKSG", "length": 474 }, "evidence": [ { "id": "HGNC:6677", "url": "https://alliancegenome.org/gene/HGNC:6677#orthology", "database": "AGR" }, { "id": "MGI:96820", "url": "https://alliancegenome.org/gene/MGI:96820#orthology", "database": "AGR" }, { "id": "RGD:3017", "url": "https://alliancegenome.org/gene/RGD:3017#orthology", "database": "AGR" }, { "id": "FB:FBgn0030828", "url": "https://alliancegenome.org/gene/FB:FBgn0030828#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P27656-1", "protein_name": "Hepatic triacylglycerol lipase", "gene_name": "Lipc", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGNPLQISIFLVFCIFIQSSACGQGVGTEPFGRSLGATEASKPLKKPETRFLLFQDENDRLGCRLRPQHPETLQECGFNSSQPLIMIIHGWSVDGLLENWIWKIVSALKSRQSQPVNVGLVDWISLAYQHYTIAVQNTRIVGQDVAALLLWLEESAKFSRSKVHLIGYSLGAHVSGFAGSSMDGKNKIGRITGLDPAGPMFEGTSPNERLSPDDANFVDAIHTFTREHMGLSVGIKQPIAHYDFYPNGGSFQPGCHFLELYKHIAEHGLNAITQTIKCAHERSVHLFIDSLQHSDLQSIGFQCSDMGSFSQGLCLSCKKGRCNTLGYDIRKDRSGKSKRLFLITRAQSPFKVYHYQFKIQFINQIEKPVEPTFTMSLLGTKEEIKRIPITLGEGITSNKTYSFLITLDKDIGELILLKFKWENSAVWANVWNTVQTIMLWGIEPHHSGLILKTIWVKAGETQQRMTFCPENLDDLQLHPSQEKVFVNCEVKSKRLTESKEQMSQETHAKK", "length": 510 }, "evidence": [ { "id": "HGNC:6619", "url": "https://alliancegenome.org/gene/HGNC:6619#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q06000-1", "protein_name": "Lipoprotein lipase", "gene_name": "Lpl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESKALLLVALGVWLQSLTAFRGGVAAADGGRDFSDIESKFALRTPEDTAEDTCHLIPGLADSVSNCHFNHSSKTFVVIHGWTVTGMYESWVPKLVAALYKREPDSNVIVVDWLYRAQQHYPVSAGYTKLVGNDVARFINWLEEEFNYPLDNVHLLGYSLGAHAAGVAGSLTNKKVNRITGLDPAGPNFEYAEAPSRLSPDDADFVDVLHTFTRGSPGRSIGIQKPVGHVDIYPNGGTFQPGCNIGEAIRVIAEKGLGDVDQLVKCSHERSIHLFIDSLLNEENPSKAYRCNSKEAFEKGLCLSCRKNRCNNVGYEINKVRAKRSSKMYLKTRSQMPYKVFHYQVKIHFSGTENDKQNNQAFEISLYGTVAESENIPFTLPEVATNKTYSFLIYTEVDIGELLMMKLKWKNDSYFRWSDWWSSPSFVIEKIRVKAGETQKKVIFCAREKVSHLQKGKDAAVFVKCHDKSLKKSG", "length": 474 }, "evidence": [ { "id": "HGNC:6677", "url": "https://alliancegenome.org/gene/HGNC:6677#orthology", "database": "AGR" }, { "id": "MGI:96820", "url": "https://alliancegenome.org/gene/MGI:96820#orthology", "database": "AGR" }, { "id": "RGD:3017", "url": "https://alliancegenome.org/gene/RGD:3017#orthology", "database": "AGR" }, { "id": "FB:FBgn0030828", "url": "https://alliancegenome.org/gene/FB:FBgn0030828#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8VBX1-1", "protein_name": "Endothelial lipase", "gene_name": "Lipg", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRDPVFLLGFWSLYCCFPAGSLTTLRPQGSLRDEHHKPTGVPVTITTKPSVTFNIRTSKDPEHEGCNLSLGDSKLLENCGFNMTAKTFFIIHGWTMSGMFESWLHKLVSALQTREKEANVVVVDWLPLAHQLYIDAVSNTRVVGRRVAGMLNWLQEKGEFSLGDVHLIGYSLGAHVAGYAGNFVKGTVGRITGLDPAGPMFEGVDINRRLSPDDADFVDVLHTYTLSFGLSIGIRMPVGHIDIYPNGGDFQPGCGFNDVMGSFAYGTISEMVKCEHERAVHLFVDSLVNQDKPSFAFQCTDPNRFKRGICLSCRKNRCNNIGYNAKKMRKKRNSKMYLKTRAGMPFRVYHYQLKVHMFSYKNSGDIQPDLYITLYGSNADSQNLPLEIVEKIELNATNTFLVYTEEYLGDLFKIRLTWEGVSSSWYNLWNEFRSYLSQPSSPSRELHIRRIRVKSGETQRKVAFCVQDPMKNSISPGQELWFYKCQNDCRVKN", "length": 493 }, "evidence": [ { "id": "HGNC:6623", "url": "https://alliancegenome.org/gene/HGNC:6623#orthology", "database": "AGR" }, { "id": "RGD:1310740", "url": "https://alliancegenome.org/gene/RGD:1310740#orthology", "database": "AGR" }, { "id": "FB:FBgn0030828", "url": "https://alliancegenome.org/gene/FB:FBgn0030828#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9VJH1-1", "protein_name": "Lipase domain-containing protein", "gene_name": "Dmel\\CG13282", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MHWRLVIGLLLLASFNRETIGKRFLNLKPIPIQHEDESSTEGSTNPTPTSTTTPSNRDITIGPCKWAIGRSCPDPDVKYYIYTRHNPMDRQCLHIDESLEKSNLTDSYFNPRYPTKIIIHGYNSDMFLHPLQQMREEYLAKADYNIIYVDWSILSPGPCYISAVHNTKHAGTCTAQLVERLVETGNTDIHVIGFSLGAQVPNYIARNLSSFMLPRITGLDPAMPLFITSGKADKLDPSDASYVDVIHTNALVQGKMERCGHADFYMNGGIMQPGCNGQKINSFACSHQRAPAYFLESIRSPKGFWGWACSGYISYLLGMCPPTNFLLEAGENIRPTTRGMFMIDTNDSSPFALGKWTDLPTLGAKQPQWRVPTQKLKAPPNQGVDPLLHHIDQFGKLAANFNNLQMWPTEQDPYEHWTSFSPEQKENDSDGDSVEEQDPVEFIEPDDRQMISTEARPTQSWWDYRRNLTYGFMEDNIFSVPTVD", "length": 484 }, "evidence": [ { "id": "HGNC:6619", "url": "https://alliancegenome.org/gene/HGNC:6619#orthology", "database": "AGR" }, { "id": "HGNC:6623", "url": "https://alliancegenome.org/gene/HGNC:6623#orthology", "database": "AGR" }, { "id": "HGNC:6677", "url": "https://alliancegenome.org/gene/HGNC:6677#orthology", "database": "AGR" }, { "id": "MGI:96820", "url": "https://alliancegenome.org/gene/MGI:96820#orthology", "database": "AGR" }, { "id": "RGD:1310740", "url": "https://alliancegenome.org/gene/RGD:1310740#orthology", "database": "AGR" }, { "id": "RGD:3017", "url": "https://alliancegenome.org/gene/RGD:3017#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VQC2-1", "protein_name": "Lipase domain-containing protein", "gene_name": "Dmel\\CG18641", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MWLQCARKPIRADFWLQLLCVSFTLFHLEFAAAQNAGVVAAAVAAGQNQTQVYVTDSCLQKPYRCPHPKIQFYLYTRRTQEQPEFIDVLDPNALYYTHFNPRHPTKIIIHGFGGGRTLSPSPDLREAYFSVGEYNIIIVDYADAVKEPCLSQMDWAPRFGSLCISQLVKYLARHPRGVQPDDLHFIGYSVGAHIAGLVANYLKPEEGKLGRITALDPTIFFYAGANNSRDLDSTDAHFVDVLHTGAGILGQWHSSGHADFYVNGGTRQPACVGSATLFQTLACDHTKVTPYFIESITTTRGFYAGPCPNLFSYLIGWCEPKDSEYVLMGEHCSHKARGNYYVTTNAKAPFARGFPGKGRSNGEYQGVRR", "length": 369 }, "evidence": [ { "id": "HGNC:6619", "url": "https://alliancegenome.org/gene/HGNC:6619#orthology", "database": "AGR" }, { "id": "HGNC:6623", "url": "https://alliancegenome.org/gene/HGNC:6623#orthology", "database": "AGR" }, { "id": "HGNC:6677", "url": "https://alliancegenome.org/gene/HGNC:6677#orthology", "database": "AGR" }, { "id": "MGI:96820", "url": "https://alliancegenome.org/gene/MGI:96820#orthology", "database": "AGR" }, { "id": "RGD:1310740", "url": "https://alliancegenome.org/gene/RGD:1310740#orthology", "database": "AGR" }, { "id": "RGD:3017", "url": "https://alliancegenome.org/gene/RGD:3017#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VRW5-1", "protein_name": "Lipase domain-containing protein", "gene_name": "Dmel\\CG10163", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRAQFTMQKSTAQMIIAVCLICQSLAVEDKDKATNPLNIDSVQKHNVKLLSEQLNRGWRAFCDAPVDEGVMSLFQGINPSDARLHVMTITNQSVELPIKSISQIKDFDINPERKTLIYVNAFHTADSYFSVQEHLTLLQNSRRDLNVIVVDFAKDVAQLYYAVRHHLSVNGYFVYKLLRALKDAGIAVQDITLAGHSVGANIAALGAQLFAKENKQLVGQLLAIDPATMCRTTDILVKQSVALRVVVLHGEGDVFGVRVPLGHIDIYPNGIGYFPRRKLQPGCESKICSHMYPFILFMEALIEGVMIPATKCESWAKFRQGDCNFQNTINIGLIYPANAKGLYFCMTQPNPPFTYMEHGLRYKARRPEKSSEKNRIKF", "length": 378 }, "evidence": [ { "id": "HGNC:6619", "url": "https://alliancegenome.org/gene/HGNC:6619#orthology", "database": "AGR" }, { "id": "HGNC:6623", "url": "https://alliancegenome.org/gene/HGNC:6623#orthology", "database": "AGR" }, { "id": "HGNC:6677", "url": "https://alliancegenome.org/gene/HGNC:6677#orthology", "database": "AGR" }, { "id": "MGI:96820", "url": "https://alliancegenome.org/gene/MGI:96820#orthology", "database": "AGR" }, { "id": "RGD:1310740", "url": "https://alliancegenome.org/gene/RGD:1310740#orthology", "database": "AGR" }, { "id": "RGD:3017", "url": "https://alliancegenome.org/gene/RGD:3017#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VU78-1", "protein_name": "Lipase domain-containing protein", "gene_name": "Dmel\\CG10116", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MQTGVQLALFLTLTIAAVYGETGFFLNTRRVQENAQPIEAEVEALVRSSFYAADPTVVTIPRWLGNISSPEIPAVVSARLQQQDSNIISVDLSEANDETEIIDSVASLVIVLHNQFDMPLDRILVVGFAEGAHLAGGVAAKVQQDLGRQLSQITALDPSSGAELDHKLSQADAEFVEVVHTNAGGEGTWERLGHVDYYPNGGQTQPGCTTDSCSHERAFELLAEMWSPENDFVSARCGSVETLSASSCRWSTHKMGQKQEEEQPASGIYFLETRQSSPFSRGAYFISFL", "length": 289 }, "evidence": [ { "id": "HGNC:6619", "url": "https://alliancegenome.org/gene/HGNC:6619#orthology", "database": "AGR" }, { "id": "HGNC:6623", "url": "https://alliancegenome.org/gene/HGNC:6623#orthology", "database": "AGR" }, { "id": "HGNC:6677", "url": "https://alliancegenome.org/gene/HGNC:6677#orthology", "database": "AGR" }, { "id": "MGI:96820", "url": "https://alliancegenome.org/gene/MGI:96820#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VX70-1", "protein_name": "Lipase domain-containing protein", "gene_name": "CT41369", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSSSIAVVLVVVLIGISESIKTDSLMMTSSLTPEISKSDKLKLIVSQNAESSKDTDAIETDISNEHDPRDALKDSSSPDADVLRNKTTEGLISLNNKAENTMTGLDDSESLKLARPASSYQEALLNRLQDQLNQFVVGLPLDLGFSTLNYICSTIVDLGVVRSKLIPDMSRMSFLLRSSDDCQNTSIPLTQAEQLWNTTGFYQDRPTVLFITGWTTSINNSNSGPVAKAYLCRNDTNVLILDAANFIDTLYTWSALNTEVIGDYLAKALLRLNTSYVTKQFHLVGHSLGAQIAGSAGRNYRRLSGGQILKRITGLDPANPCFYDGNELEGLRSGDARFVDIIHTNPGMFGTSKRAGDADFFVQGRIPFKPGCESLDPISCSHQRAVDYWTETVYPSNGNDFLAKRCKRYSELLLGNYCKNTNTVMGYAAKATDLGLFYVGANPEEPYGQNANLQSYTNSDTKCGSCAS", "length": 468 }, "evidence": [ { "id": "HGNC:6619", "url": "https://alliancegenome.org/gene/HGNC:6619#orthology", "database": "AGR" }, { "id": "HGNC:6623", "url": "https://alliancegenome.org/gene/HGNC:6623#orthology", "database": "AGR" }, { "id": "HGNC:6677", "url": "https://alliancegenome.org/gene/HGNC:6677#orthology", "database": "AGR" }, { "id": "MGI:96820", "url": "https://alliancegenome.org/gene/MGI:96820#orthology", "database": "AGR" }, { "id": "RGD:1310740", "url": "https://alliancegenome.org/gene/RGD:1310740#orthology", "database": "AGR" }, { "id": "RGD:3017", "url": "https://alliancegenome.org/gene/RGD:3017#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9WVG5-1", "protein_name": "Endothelial lipase", "gene_name": "Lipg", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRNTVFLLGFWSVYCYFPAGSITTLRPQGSLRDEHHKPTGVPATARPSVAFNIRTSKDPEQEGCNLSLGDSKLLENCGFNMTAKTFFIIHGWTMSGMFESWLHKLVSALQMREKDANVVVVDWLPLAHQLYTDAVNNTRVVGQRVAGMLDWLQEKEEFSLGNVHLIGYSLGAHVAGYAGNFVKGTVGRITGLDPAGPMFEGVDINRRLSPDDADFVDVLHTYTLSFGLSIGIRMPVGHIDIYPNGGDFQPGCGFNDVIGSFAYGTISEMVKCEHERAVHLFVDSLVNQDKPSFAFQCTDSSRFKRGICLSCRKNRCNNIGYNAKKMRKKRNSKMYLKTRAGMPFKVYHYQLKVHMFSYNNSGDTQPTLYITLYGSNADSQNLPLEIVEKIELNATNTFLVYTEEDLGDLLKMRLTWEGVAHSWYNLWNEFRNYLSQPSNPSRELYIRRIRVKSGETQRKVTFCTQDPTKSSISPGQELWFHKCQDGWKMKNKTSPFVNLA", "length": 500 }, "evidence": [ { "id": "HGNC:6623", "url": "https://alliancegenome.org/gene/HGNC:6623#orthology", "database": "AGR" }, { "id": "RGD:1310740", "url": "https://alliancegenome.org/gene/RGD:1310740#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y5X9-1", "protein_name": "Endothelial lipase", "gene_name": "LIPG", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSNSVPLLCFWSLCYCFAAGSPVPFGPEGRLEDKLHKPKATQTEVKPSVRFNLRTSKDPEHEGCYLSVGHSQPLEDCSFNMTAKTFFIIHGWTMSGIFENWLHKLVSALHTREKDANVVVVDWLPLAHQLYTDAVNNTRVVGHSIARMLDWLQEKDDFSLGNVHLIGYSLGAHVAGYAGNFVKGTVGRITGLDPAGPMFEGADIHKRLSPDDADFVDVLHTYTRSFGLSIGIQMPVGHIDIYPNGGDFQPGCGLNDVLGSIAYGTITEVVKCEHERAVHLFVDSLVNQDKPSFAFQCTDSNRFKKGICLSCRKNRCNSIGYNAKKMRNKRNSKMYLKTRAGMPFRVYHYQMKIHVFSYKNMGEIEPTFYVTLYGTNADSQTLPLEIVERIEQNATNTFLVYTEEDLGDLLKIQLTWEGASQSWYNLWKEFRSYLSQPRNPGRELNIRRIRVKSGETQRKLTFCTEDPENTSISPGRELWFRKCRDGWRMKNETSPTVELP", "length": 500 }, "evidence": [ { "id": "HGNC:6623", "url": "https://alliancegenome.org/gene/HGNC:6623#orthology", "database": "AGR" }, { "id": "RGD:1310740", "url": "https://alliancegenome.org/gene/RGD:1310740#orthology", "database": "AGR" }, { "id": "FB:FBgn0030828", "url": "https://alliancegenome.org/gene/FB:FBgn0030828#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "insemination", "id": "GO:0007320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007320", "evidence": [ { "database": "UniProtKB", "id": "Q9VX69", "url": "https://www.uniprot.org/uniprotkb/Q9VX69" } ], "pmid": "" }, { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "Q9VX69", "url": "https://www.uniprot.org/uniprotkb/Q9VX69" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VX69", "url": "https://www.uniprot.org/uniprotkb/Q9VX69" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "lipase activity", "id": "GO:0016298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016298", "evidence": [ { "database": "UniProtKB", "id": "Q9VX69", "url": "https://www.uniprot.org/uniprotkb/Q9VX69" } ], "pmid": "" }, { "name": "serine hydrolase activity", "id": "GO:0017171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017171", "evidence": [ { "database": "UniProtKB", "id": "Q9VX69", "url": "https://www.uniprot.org/uniprotkb/Q9VX69" } ], "pmid": "" }, { "name": "triacylglycerol lipase activity", "id": "GO:0004806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004806", "evidence": [ { "database": "UniProtKB", "id": "Q9VX69", "url": "https://www.uniprot.org/uniprotkb/Q9VX69" } ], "pmid": "" } ] } ] }, 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"MIM", "url": "https://www.omim.org/entry/603278", "name": "Focal segmental glomerulosclerosis 1", "description": "Focal segmental glomerulosclerosis 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "1312", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1312" } ] }, { "disease_id": "DOID:13809", "recommended_name": { "id": "DOID:13809", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13809", "name": "familial combined hyperlipidemia", "description": "" }, "synonyms": [ { "id": "DOID:13809", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13809", "name": "familial multiple lipoprotein-type hyperlipidemia", "description": "" }, { "id": "DOID:13809", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13809", "name": "mixed hyperlipidaemia", "description": "" }, { "id": "DOID:13809", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13809", "name": "type IIb hyperlipoproteinemia", "description": "" }, { "id": "DOID:13809", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13809", "name": "hyperbetalipoproteinemia with prebetalipoproteinemia", "description": "" }, { "id": "MONDO:0007759", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007759", "name": "hyperlipidemia, familial combined, LPL related", "description": "" }, { "id": "MONDO:0007759", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007759", "name": "combined hyperlipidemia, familial", "description": "" }, { "id": "MONDO:0007759", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007759", "name": "FCHL", "description": "" }, { "id": "MONDO:0007759", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007759", "name": "hyperlipidemia, familial combined", "description": "" }, { "id": "MIM:144250", "resource": "MIM", "url": "https://www.omim.org/entry/144250", "name": "Hyperlipidemia, familial combined, 3", "description": "Hyperlipidemia, familial combined, 3" } ], "unlinked_id_list": [], "evidence": [ { "id": "13809", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13809" } ] }, { "disease_id": "DOID:14118", "recommended_name": { "id": "DOID:14118", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14118", "name": "familial lipoprotein lipase deficiency", "description": "A familial hyperlipemia characterized by a deficiency of the enzyme lipoprotein lipase and the subsequent build up of chylomicrons and increased plasma concentration of triglycerides." }, "synonyms": [ { "id": "DOID:14118", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14118", "name": "Fredrickson type I hyperlipoproteinemia", "description": "" }, { "id": "DOID:14118", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14118", "name": "Fredrickson type I lipaemia", "description": "" }, { "id": "DOID:14118", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14118", "name": "familial LPL deficiency", "description": "" }, { "id": "DOID:14118", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14118", "name": "familial hyperlipoproteinemia type I", "description": "" }, { "id": "DOID:14118", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14118", "name": "hypercholesterinaemic xanthomatosis", "description": "" }, { "id": "DOID:14118", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14118", "name": "hyperchylomicronemia", "description": "" }, { "id": "DOID:14118", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14118", "name": "mixed hyperglyceridemia", "description": "" }, { "id": "MONDO:0009387", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009387", "name": "familial lipoprotein lipase deficiency", "description": "Familial lipoprotein lipase deficiency is a rare genetic disorder is which a person lacks the enzyme lipoprotein lipase, a protein needed to break down fat molecules. Deficiency of this enzyme prevents affected individuals from properly digesting certain fats. This results in the accumulation of fatty droplets called chylomicrons in the blood and an increase in the blood concentration of triglycerides. Symptoms include episodes of abdominal pain, recurrent inflammation of the pancreas (pancreatitis), abnormal enlargement of the liver and/or spleen (hepatosplenomegaly), and the development of skin lesions known as erruptive xanthomas. Familial lipoprotein lipase deficiency is caused by changes (mutations) in the LPL gene. It is inherited in an autosomal recessive pattern. Treatment aims to control symptoms and blood triglyceride levels with a very low-fat diet. Treatment for individual symptoms (i.e. pancreatitis) involves following established treatment guidelines." }, { "id": "MONDO:0009387", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009387", "name": "familial chylomicronemia syndrome", "description": "" }, { "id": "MONDO:0009387", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009387", "name": "hyperlipoproteinemia type I", "description": "" }, { "id": "MONDO:0009387", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009387", "name": "hyperlipoproteinemia, type 1", "description": "" }, { "id": "MONDO:0009387", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009387", "name": "hyperlipoproteinemia, type I", "description": "" }, { "id": "MONDO:0009387", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009387", "name": "type I hyperlipoproteinemia", "description": "" }, { "id": "MONDO:0009387", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009387", "name": "LPL deficiency", "description": "" }, { "id": "MONDO:0009387", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009387", "name": "familial lipoprotein lipase deficiency (disorder) [ambiguous]", "description": "" }, { "id": "MONDO:0009387", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009387", "name": "familial lipoprotein lipase deficiency with type I phenotype", "description": "" }, { "id": "MONDO:0009387", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009387", "name": "high density lipoprotein cholesterol level QTL 11", "description": "" }, { "id": "MONDO:0009387", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009387", "name": "hyperchylomicronemia", "description": "" }, { "id": "MONDO:0009387", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009387", "name": "Burger-Grutz syndrome", "description": "" }, { "id": "MONDO:0009387", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009387", "name": "endogenous hypertriglyceridaemia", "description": "" }, { "id": "MONDO:0009387", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009387", "name": "familial fat-induced hypertriglyceridemia", "description": "" }, { "id": "MONDO:0009387", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009387", "name": "familial hyperchylomicronemia", "description": "" }, { "id": "MONDO:0009387", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009387", "name": "lipoprotein lipase deficiency, familial", "description": "" }, { "id": "MIM:238600", "resource": "MIM", "url": "https://www.omim.org/entry/238600", "name": "Hyperlipoproteinemia 1", "description": "Hyperlipoproteinemia 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "14118", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14118" } ] }, { "disease_id": "DOID:14221", "recommended_name": { "id": "DOID:14221", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14221", "name": "abdominal obesity-metabolic syndrome 1", "description": "An abdominal obesity-metabolic syndrome characterized by insulin resistance and hyperinsulinemia, dyslipidemia, essential hypertension, abdominal obesity, glucose intolerance or noninsulin-dependent diabetes mellitus and an increased risk of cardiovascular events." }, "synonyms": [ { "id": "DOID:14221", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14221", "name": "dysmetabolic syndrome X", "description": "" }, { "id": "DOID:14221", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14221", "name": "metabolic syndrome X", "description": "" }, { "id": "MONDO:0011565", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011565", "name": "metabolic syndrome X", "description": "" }, { "id": "MONDO:0011565", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011565", "name": "abdominal obesity-metabolic syndrome 1", "description": "" }, { "id": "MONDO:0011565", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011565", "name": "metabolic syndrome type X", "description": "" }, { "id": "MONDO:0011565", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011565", "name": "AOMS1", "description": "" }, { "id": "MONDO:0011565", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011565", "name": "abdominal obesity metabolic syndrome", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "14221", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14221" } ] }, { "disease_id": "DOID:2018", "recommended_name": { "id": "DOID:2018", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2018", "name": "hyperinsulinism", "description": "" }, "synonyms": [ { "id": "DOID:2018", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2018", "name": "hyperinsulinemia", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "2018", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2018" } ] }, { "disease_id": "DOID:3393", "recommended_name": { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "coronary artery disease", "description": "An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles." }, "synonyms": [ { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "CHD", "description": "" }, { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "Coronary disease", "description": "" }, { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "coronary arteriosclerosis", "description": "" }, { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "coronary heart disease", "description": "" }, { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "Ischemic Heart Disease", "description": "" }, { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "myocardial ischemia", "description": "" }, { "id": "MONDO:0010331", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010331", "name": "coronary heart disease, susceptibility to, 3", "description": "" }, { "id": "MONDO:0010331", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010331", "name": "coronary heart disease, susceptibility to, 3", "description": "" }, { "id": "MONDO:0010331", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010331", "name": "coronary heart disease, susceptibility to, type 3", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary heart disease, susceptibility to, 1", "description": "Any coronary artery disease in which the cause of the disease is a mutation in the CX3CR1 gene." }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "CX3CR1 coronary artery disease", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary artery disease caused by mutation in CX3CR1", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary artery disease, resistance to", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary heart disease, susceptibility to", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary heart disease, susceptibility to, 1", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary heart disease, susceptibility to, type 1", "description": "" }, { "id": "MONDO:0012009", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012009", "name": "coronary heart disease, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012009", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012009", "name": "coronary heart disease, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012009", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012009", "name": "coronary heart disease, susceptibility to, type 2", "description": "" }, { "id": "MONDO:0012010", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012010", "name": "coronary heart disease, susceptibility to, 4", "description": "" }, { "id": "MONDO:0012010", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012010", "name": "coronary heart disease, susceptibility to, 4", "description": "" }, { "id": "MONDO:0012010", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012010", "name": "coronary heart disease, susceptibility to, type 4", "description": "" }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "coronary artery disease, autosomal dominant, 1", "description": "Any coronary artery disease in which the cause of the disease is a mutation in the MEF2A gene." }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "MEF2A coronary artery disease", "description": "" }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "coronary artery disease caused by mutation in MEF2A", "description": "" }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "coronary artery disease, autosomal dominant, 1", "description": "" }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "coronary artery disease, autosomal dominant, type 1", "description": "" }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "ADCAD1", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "coronary artery disease, autosomal dominant 2", "description": "Any coronary artery disease in which the cause of the disease is a mutation in the LRP6 gene." }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "LRP6 coronary artery disease", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "coronary artery disease caused by mutation in LRP6", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "coronary artery disease, autosomal dominant 2", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "coronary artery disease, autosomal dominant type 2", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "coronary artery disease, autosomal dominant, 2", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "ADCAD2", "description": "" }, { "id": "MONDO:0012628", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012628", "name": "coronary heart disease, susceptibility to, 8", "description": "" }, { "id": "MONDO:0012628", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012628", "name": "CHDS8", "description": "" }, { "id": "MONDO:0012628", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012628", "name": "coronary heart disease, susceptibility to, 8", "description": "" }, { "id": "MONDO:0012788", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012788", "name": "coronary heart disease, susceptibility to, 9", "description": "" }, { "id": "MONDO:0012788", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012788", "name": "CHDS9", "description": "" }, { "id": "MONDO:0012788", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012788", "name": "coronary heart disease, susceptibility to, 9", "description": "" }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "hydatidiform mole, recurrent, 2", "description": "Any complete hydatidiform mole in which the cause of the disease is a mutation in the KHDC3L gene." }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "KHDC3L complete hydatidiform mole", "description": "" }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "complete hydatidiform mole caused by mutation in KHDC3L", "description": "" }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "hydatidiform Mole, recurrent, type 2", "description": "" }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "hydatidiform mole, recurrent, 2", "description": "" }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "HYDM2", "description": "" }, { "id": "MIM:608320", "resource": "MIM", "url": "https://www.omim.org/entry/608320", "name": "Coronary artery disease, autosomal dominant, 1", "description": "Coronary artery disease, autosomal dominant, 1" }, { "id": "MIM:610947", "resource": "MIM", "url": "https://www.omim.org/entry/610947", "name": "Coronary artery disease, autosomal dominant, 2", "description": "Coronary artery disease, autosomal dominant, 2" }, { "id": "MIM:614293", "resource": "MIM", "url": "https://www.omim.org/entry/614293", "name": "Hydatidiform mole, recurrent, 2", "description": "Hydatidiform mole, recurrent, 2" } ], "unlinked_id_list": [ "DOID:11840" ], "evidence": [ { "id": "3393", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3393" } ] }, { "disease_id": "DOID:341", "recommended_name": { "id": "DOID:341", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:341", "name": "peripheral vascular disease", "description": "A vascular disease that is characterized by obstruction of vessels not within the coronary, aortic arch vasculature, or brain." }, "synonyms": [ { "id": "DOID:341", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:341", "name": "arterial occlusive disease", "description": "" } ], "unlinked_id_list": [ "DOID:1729" ], "evidence": [ { "id": "341", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:341" } ] }, { "disease_id": "DOID:3526", "recommended_name": { "id": "DOID:3526", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3526", "name": "cerebral infarction", "description": "A cerebrovascular disease that is characterized by an area of necrotic tissue in the brain resulting from a blockage or narrowing in the arteries supplying blood and oxygen to the brain." }, "synonyms": [ { "id": "DOID:3526", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3526", "name": "Cerebral infarct", "description": "" }, { "id": "MONDO:0020671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0020671", "name": "obsolete susceptibility to ischemic stroke", "description": "" }, { "id": "MONDO:0020671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0020671", "name": "cerebral infarction, susceptibility to", "description": "" }, { "id": "MONDO:0020671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0020671", "name": "ischemic stroke, susceptibility to", "description": "" }, { "id": "MONDO:0020671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0020671", "name": "stroke, ischemic, susceptibility to", "description": "" }, { "id": "MONDO:0020671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0020671", "name": "stroke, susceptibility to", "description": "" }, { "id": "MIM:601367", "resource": "MIM", "url": "https://www.omim.org/entry/601367", "name": "Ischemic stroke", "description": "Ischemic stroke" } ], "unlinked_id_list": [], "evidence": [ { "id": "3526", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3526" } ] }, { "disease_id": "DOID:557", "recommended_name": { "id": "DOID:557", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:557", "name": "kidney disease", "description": "A urinary system disease that is located_in the kidney." }, "synonyms": [ { "id": "DOID:557", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:557", "name": "nephropathy", "description": "" }, { "id": "DOID:557", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:557", "name": "impaired renal function disease", "description": "" } ], "unlinked_id_list": [ "DOID:0081055", "DOID:3116", "DOID:13138", "DOID:3675", "DOID:4455", "DOID:0080616", "DOID:2744", "DOID:9808", "DOID:582" ], "evidence": [ { "id": "557", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:557" } ] }, { "disease_id": "DOID:5844", "recommended_name": { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia." }, "synonyms": [ { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "Myocardial infarct", "description": "" }, { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "heart attack", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, type 2", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ] }, { "disease_id": "DOID:783", "recommended_name": { "id": "DOID:783", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:783", "name": "end stage renal disease", "description": "A chronic kidney disease is characterized by non-functioning kidneys, as the final stage in chronic kidney disease." }, "synonyms": [ { "id": "DOID:783", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:783", "name": "end stage renal failure", "description": "" }, { "id": "DOID:783", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:783", "name": "end-stage kidney disease", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "783", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:783" } ] }, { "disease_id": "DOID:9352", "recommended_name": { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin." }, "synonyms": [ { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "NIDDM", "description": "" }, { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "non-insulin-dependent diabetes mellitus", "description": "" }, { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "type 2 diabetes", "description": "" }, { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "type II diabetes mellitus", "description": "" }, { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "insulin resistance", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type 2 diabetes mellitus", "description": "A type of diabetes mellitus that is characterized by insulin resistance or desensitization and increased blood glucose levels. This is a chronic disease that can develop gradually over the life of a patient and can be linked to both environmental factors and heredity." }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "NIDDM", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "T2D", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "T2DM", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "T2DM - type 2 diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "adult onset diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "adult-onset diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitis type 2", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitis type II", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent, association with", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent, late onset", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, type 2", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, type II", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes, type 2", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "insulin resistance, severe, digenic", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "non-insulin dependent diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "non-insulin dependent diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "noninsulin dependent diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "noninsulin-dependent diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type 2 diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type 2 diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type 2 diabetes mellitus non-insulin dependent", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type II diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type II diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent, 2", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "diabetes mellitus, noninsulin-dependent, 1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "diabetes mellitus, noninsulin-dependent 1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "diabetes mellitus, noninsulin-dependent, 1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "diabetes mellitus, noninsulin-dependent, type 1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "NIDDM1", "description": "" }, { "id": "MONDO:0011072", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011072", "name": "diabetes mellitus, noninsulin-dependent, 2", "description": "" }, { "id": "MONDO:0011072", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011072", "name": "NIDDM2", "description": "" }, { "id": "MONDO:0011072", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011072", "name": "diabetes mellitus, noninsulin-dependent, 2", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "diabetes mellitus, noninsulin-dependent, 3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "diabetes mellitus, noninsulin-dependent, 3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "diabetes mellitus, noninsulin-dependent, type 3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "type 2 diabetes mellitus 3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "NIDDM3", "description": "" }, { "id": "MONDO:0011955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011955", "name": "diabetes mellitus, noninsulin-dependent, 4", "description": "" }, { "id": "MONDO:0011955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011955", "name": "diabetes mellitus, noninsulin-dependent, 4", "description": "" }, { "id": "MONDO:0011955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011955", "name": "diabetes mellitus, noninsulin-dependent, type 4", "description": "" }, { "id": "MIM:125853", "resource": "MIM", "url": "https://www.omim.org/entry/125853", "name": "Type 2 diabetes mellitus", "description": "Type 2 diabetes mellitus" }, { "id": "MIM:601283", "resource": "MIM", "url": "https://www.omim.org/entry/601283", "name": "Type 2 diabetes mellitus 1", "description": "Type 2 diabetes mellitus 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ] }, { "disease_id": "DOID:9744", "recommended_name": { "id": "DOID:9744", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9744", "name": "type 1 diabetes mellitus", "description": "A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production." }, "synonyms": [ { "id": "DOID:9744", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9744", "name": "IDDM", "description": "" }, { "id": "DOID:9744", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9744", "name": "insulin-dependent diabetes mellitus", "description": "" }, { "id": "DOID:9744", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9744", "name": "type I diabetes mellitus", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "type 1 diabetes mellitus", "description": "A chronic condition characterized by minimal or absent production of insulin by the pancreas." }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "IDDM", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "T1D", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "T1DM", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "diabetes mellitis type 1", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "diabetes mellitis type I", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "immune mediated diabetes", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "insulin dependent diabetes", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "juvenile diabetes", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "type 1 diabetes", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "type I diabetes", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "type I diabetes mellitus", "description": "" }, { "id": "MIM:222100", "resource": "MIM", "url": "https://www.omim.org/entry/222100", "name": "Type 1 diabetes mellitus", "description": "Type 1 diabetes mellitus" } ], "unlinked_id_list": [], "evidence": [ { "id": "9744", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9744" } ] }, { "disease_id": "DOID:9970", "recommended_name": { "id": "DOID:9970", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness." }, "synonyms": [ { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "inherited obesity", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "genetic obesity", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "genetic obesity (disease)", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "leanness, inherited, autosomal recessive", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "monogenic obesity", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "obesity, association with, Autosomal recessive", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "obesity, early-onset, susceptibility to, Autosomal recessive", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "obesity, late-onset, Autosomal recessive", 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"categories": [ "Gene Expression" ] }, { "id": "cd00707", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00707", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0265267", "url": "https://flybase.org/reports/FBgn0265267", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "32708", "url": "https://www.ncbi.nlm.nih.gov/gene/32708", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013818", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013818", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033906", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033906", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG18258", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG18258", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IPDMSRM", "url": "https://omabrowser.org/oma/group/IPDMSRM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VX70", "url": "https://www.orthodb.org/?gene=Q9VX70", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11610", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11610", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11610:SF149", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11610:SF149", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00151", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00151", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-192456", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-192456", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-8963889", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8963889", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-8964058", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8964058", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_573201", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573201", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VX70", "url": "https://www.uniprot.org/uniprotkb/Q9VX70", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VX70-1", "url": "https://www.uniprot.org/uniprotkb/Q9VX70-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSSIAVVLVVVLIGISESIKTDSLMMTSSLTPEISKSDKLKLIVSQNAESSKDTDAIETDISNEHDPRDALKDSSSPDADVLRNKTTEGLISLNNKAENTMTGLDDSESLKLARPASSYQEALLNRLQDQLNQFVVGLPLDLGFSTLNYICSTIVDLGVVRSKLIPDMSRMSFLLRSSDDCQNTSIPLTQAEQLWNTTGFYQDRPTVLFITGWTTSINNSNSGPVAKAYLCRNDTNVLILDAANFIDTLYTWSALNTEVIGDYLAKALLRLNTSYVTKQFHLVGHSLGAQIAGSAGRNYRRLSGGQILKRITGLDPANPCFYDGNELEGLRSGDARFVDIIHTNPGMFGTSKRAGDADFFVQGRIPFKPGCESLDPISCSHQRAVDYWTETVYPSNGNDFLAKRCKRYSELLLGNYCKNTNTVMGYAAKATDLGLFYVGANPEEPYGQNANLQSYTNSDTKCGSCAS", "length": 468, "header": "tr|Q9VX70-1|Q9VX70_DROME Isoform 1 of Lipase domain-containing protein OS=Drosophila melanogaster OX=7227 GN=CT41369 PE=3 SV=2 CANONICAL=Q9VX70-1" }, "isoforms": [ { "isoform_ac": "Q9VX70-1", "url": "https://www.uniprot.org/uniprotkb/Q9VX70/entry#Q9VX70-1", "sequence": { "sequence": "MSSSIAVVLVVVLIGISESIKTDSLMMTSSLTPEISKSDKLKLIVSQNAESSKDTDAIETDISNEHDPRDALKDSSSPDADVLRNKTTEGLISLNNKAENTMTGLDDSESLKLARPASSYQEALLNRLQDQLNQFVVGLPLDLGFSTLNYICSTIVDLGVVRSKLIPDMSRMSFLLRSSDDCQNTSIPLTQAEQLWNTTGFYQDRPTVLFITGWTTSINNSNSGPVAKAYLCRNDTNVLILDAANFIDTLYTWSALNTEVIGDYLAKALLRLNTSYVTKQFHLVGHSLGAQIAGSAGRNYRRLSGGQILKRITGLDPANPCFYDGNELEGLRSGDARFVDIIHTNPGMFGTSKRAGDADFFVQGRIPFKPGCESLDPISCSHQRAVDYWTETVYPSNGNDFLAKRCKRYSELLLGNYCKNTNTVMGYAAKATDLGLFYVGANPEEPYGQNANLQSYTNSDTKCGSCAS", "length": 468, "header": "tr|Q9VX70-1|Q9VX70_DROME Isoform 1 of Lipase domain-containing protein OS=Drosophila melanogaster OX=7227 GN=CT41369 PE=3 SV=2 CANONICAL=Q9VX70-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VX70", "url": "https://www.uniprot.org/uniprotkb/Q9VX70" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VX70", "url": "https://www.uniprot.org/uniprotkb/Q9VX70" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VX70", "url": "https://www.uniprot.org/uniprotkb/Q9VX70" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VX70", "url": "https://www.uniprot.org/uniprotkb/Q9VX70" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VX70", "url": "https://www.uniprot.org/uniprotkb/Q9VX70" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VX70", "url": "https://www.uniprot.org/uniprotkb/Q9VX70" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VX70", "url": "https://www.uniprot.org/uniprotkb/Q9VX70" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VX70", "url": "https://www.uniprot.org/uniprotkb/Q9VX70" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VX70", "url": "https://www.uniprot.org/uniprotkb/Q9VX70" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VX70", "url": "https://www.uniprot.org/uniprotkb/Q9VX70" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VX70", "url": "https://www.uniprot.org/uniprotkb/Q9VX70" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG18258", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG18258", "resource": "KEGG Pathway" }, { "id": "R-DME-192456", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-192456", "resource": "Reactome", "description": "Digestion of dietary lipid" }, { "id": "R-DME-8963889", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8963889", "resource": "Reactome", "description": "Assembly of active LPL and LIPC lipase complexes" }, { "id": "R-DME-8964058", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8964058", "resource": "Reactome", "description": "HDL remodeling" } ], "orthologs": [ { "uniprot_canonical_ac": "A8DYT7-1", "protein_name": "Lipase domain-containing protein", "gene_name": "CG9966", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSIYSTLILLLTIVSGFCKGENHTRGWLPEFCVVGEQKCPNSRVSFWLYTNQTRDDPIQLDPLNPQKDVFQPRLPLKILIHGFIGNRNLTPNLEVRDVLLQTQPINVISVDYGTLVRWPCYYPWAVNNAPIVSECLAQMINNLISAGISRREDIHLIGFSLGAQVAGMVANYVSQPLARITGLDPAGPGFMMQPSLQQKLDASDADFVDIIHTDPFFFSMLPPMGHADFYPNLDQLNQRGCSYISNWRFYNCNHYRAAVYYGESIISERGFWAQQCGGWFDFFSQRCSHYSNMPNTQMGYFVSEDASGSYFLTTHEVAPFAKGPLVEVEFDVSELRNFTEIELR", "length": 344 }, "evidence": [ { "id": "HGNC:6619", "url": "https://alliancegenome.org/gene/HGNC:6619#orthology", "database": "AGR" }, { "id": "HGNC:6623", "url": "https://alliancegenome.org/gene/HGNC:6623#orthology", "database": "AGR" }, { "id": "HGNC:6677", "url": "https://alliancegenome.org/gene/HGNC:6677#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "M9MRT1-1", "protein_name": "Lipase domain-containing protein", "gene_name": "chr2L_10724193_10724543.0", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDKMLTSLIALLLSLLSLNPITNASKYHREALQFLLRNGNFDLNPLNCHILLWETCPKRFIDYQLFTSNGPRRGTPLNVKNPITLYKGGFSKHRETVFIIHGFNGTAIDIHLQFLRDAYLSRDFNVITVDWRPLTRYPCYLHSLINTRLTAQCTAQIYAFLTHYGAVRERITCVGHSLGAHICGMISNHLTRKQYRIIGLDPARPLIERMKSNKFRLSIDDANVIQVLHTNAGFLGQEDNSGHLNYCVNGGRIQPFCKGNPIRKSRCSHFLSICYLATATFKHNKFMGVPCPNGCLNLSGSKRLPVSGKVNPFEFASLIREYHIGNDAPDDARGCICIDVPYAKHCPFTDA", "length": 351 }, "evidence": [ { "id": "HGNC:6619", "url": "https://alliancegenome.org/gene/HGNC:6619#orthology", "database": "AGR" }, { "id": "HGNC:6623", "url": "https://alliancegenome.org/gene/HGNC:6623#orthology", "database": "AGR" }, { "id": "HGNC:6677", "url": "https://alliancegenome.org/gene/HGNC:6677#orthology", "database": "AGR" }, { "id": "MGI:96820", "url": "https://alliancegenome.org/gene/MGI:96820#orthology", "database": "AGR" }, { "id": "RGD:1310740", "url": "https://alliancegenome.org/gene/RGD:1310740#orthology", "database": "AGR" }, { "id": "RGD:3017", "url": "https://alliancegenome.org/gene/RGD:3017#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "M9NFL7-1", "protein_name": "Lipase domain-containing protein", "gene_name": "cg5665", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRILCGIVILLRLGALGDIAVDEEGRLTRSWWDAVPRLLTDIATIKANILTAAPLELASNIIDAVCSSTLFMDRIPAQITPDIRKMHFQYMTPCQNYSVPLLEASKLWKHSRFSKGRKVVILATGWTNTVNESSAISMISKAFMCRGDVNFVIVDAADYVDTFYAWSALNTDLIGEHIGVGLTHLIELTPLRNIHLIGGFIKESFVSINSGSDFFVGHSLGAHIMGTAGRTFKKLTGKLIPRITGLDPAKPCFRREKILPGLTRGDAKLVDIIHTNIGILAKRGPLGDVDFYPGGAHPIQPGCLTIGCSHTRAVEYFAESAYPHQEKNFMGKKCASWDELRKRDCSAGIVSPMGYRMNPQARGIYYVDVNGWPPYGRNSENTVDPRLKTCYLCRR", "length": 395 }, "evidence": [ { "id": "HGNC:6619", "url": "https://alliancegenome.org/gene/HGNC:6619#orthology", "database": "AGR" }, { "id": "HGNC:6623", "url": "https://alliancegenome.org/gene/HGNC:6623#orthology", "database": "AGR" }, { "id": "HGNC:6677", "url": "https://alliancegenome.org/gene/HGNC:6677#orthology", "database": "AGR" }, { "id": "MGI:96820", "url": "https://alliancegenome.org/gene/MGI:96820#orthology", "database": "AGR" }, { "id": "RGD:1310740", "url": "https://alliancegenome.org/gene/RGD:1310740#orthology", "database": "AGR" }, { "id": "RGD:3017", "url": "https://alliancegenome.org/gene/RGD:3017#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P06858-1", "protein_name": "Lipoprotein lipase", "gene_name": "LPL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESKALLVLTLAVWLQSLTASRGGVAAADQRRDFIDIESKFALRTPEDTAEDTCHLIPGVAESVATCHFNHSSKTFMVIHGWTVTGMYESWVPKLVAALYKREPDSNVIVVDWLSRAQEHYPVSAGYTKLVGQDVARFINWMEEEFNYPLDNVHLLGYSLGAHAAGIAGSLTNKKVNRITGLDPAGPNFEYAEAPSRLSPDDADFVDVLHTFTRGSPGRSIGIQKPVGHVDIYPNGGTFQPGCNIGEAIRVIAERGLGDVDQLVKCSHERSIHLFIDSLLNEENPSKAYRCSSKEAFEKGLCLSCRKNRCNNLGYEINKVRAKRSSKMYLKTRSQMPYKVFHYQVKIHFSGTESETHTNQAFEISLYGTVAESENIPFTLPEVSTNKTYSFLIYTEVDIGELLMLKLKWKSDSYFSWSDWWSSPGFAIQKIRVKAGETQKKVIFCSREKVSHLQKGKAPAVFVKCHDKSLNKKSG", "length": 475 }, "evidence": [ { "id": "HGNC:6677", "url": "https://alliancegenome.org/gene/HGNC:6677#orthology", "database": "AGR" }, { "id": "MGI:96820", "url": "https://alliancegenome.org/gene/MGI:96820#orthology", "database": "AGR" }, { "id": "RGD:3017", "url": "https://alliancegenome.org/gene/RGD:3017#orthology", "database": "AGR" }, { "id": "FB:FBgn0265267", "url": "https://alliancegenome.org/gene/FB:FBgn0265267#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P07867-1", "protein_name": "Hepatic triacylglycerol lipase", "gene_name": "Lipc", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGNHLQISVSLVLCIFIQSSACGQGVGTEPFGRNLGATEERKPLQKPEIRFLLFKDESDRLGCQLRPQHPETLQECGFNSSHPLVMIIHGWSVDGLLETWIWKIVGALKSRQSQPVNVGLVDWISLAYQHYAIAVRNTRVVGQEVAALLLWLEESMKFSRSKVHLIGYSLGAHVSGFAGSSMGGKRKIGRITGLDPAGPMFEGTSPNERLSPDDANFVDAIHTFTREHMGLSVGIKQPIAHYDFYPNGGSFQPGCHFLELYKHIAEHGLNAITQTINCAHERSVHLFIDSLQHSNLQNTGFQCSNMDSFSQGLCLNCKKGRCNSLGYDIRRIGHVKSKTLFLITRAQSPFKVYHYQFKIQFINQMEKPMEPTFTMTLLGTKEEIKKIPITLGEGITSNKTYSLLITLNKDIGELIMLKFKWENSAVWANVWNTVQTIMLWDTEPHYAGLIVKTIWVKAGETQQRMTFCPDNVDDLQLHPTQEKVFVKCDLKSKD", "length": 494 }, "evidence": [ { "id": "HGNC:6619", "url": "https://alliancegenome.org/gene/HGNC:6619#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P11150-1", "protein_name": "Hepatic triacylglycerol lipase", "gene_name": "LIPC", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDTSPLCFSILLVLCIFIQSSALGQSLKPEPFGRRAQAVETNKTLHEMKTRFLLFGETNQGCQIRINHPDTLQECGFNSSLPLVMIIHGWSVDGVLENWIWQMVAALKSQPAQPVNVGLVDWITLAHDHYTIAVRNTRLVGKEVAALLRWLEESVQLSRSHVHLIGYSLGAHVSGFAGSSIGGTHKIGRITGLDAAGPLFEGSAPSNRLSPDDANFVDAIHTFTREHMGLSVGIKQPIGHYDFYPNGGSFQPGCHFLELYRHIAQHGFNAITQTIKCSHERSVHLFIDSLLHAGTQSMAYPCGDMNSFSQGLCLSCKKGRCNTLGYHVRQEPRSKSKRLFLVTRAQSPFKVYHYQFKIQFINQTETPIQTTFTMSLLGTKEKMQKIPITLGKGIASNKTYSFLITLDVDIGELIMIKFKWENSAVWANVWDTVQTIIPWSTGPRHSGLVLKTIRVKAGETQQRMTFCSENTDDLLLRPTQEKIFVKCEIKSKTSKRKIR", "length": 499 }, "evidence": [ { "id": "HGNC:6619", "url": "https://alliancegenome.org/gene/HGNC:6619#orthology", "database": "AGR" }, { "id": "FB:FBgn0265267", "url": "https://alliancegenome.org/gene/FB:FBgn0265267#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P11152-1", "protein_name": "Lipoprotein lipase", "gene_name": "Lpl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESKALLLVVLGVWLQSLTAFRGGVAAADAGRDFSDIESKFALRTPEDTAEDTCHLIPGLADSVSNCHFNHSSKTFVVIHGWTVTGMYESWVPKLVAALYKREPDSNVIVVDWLYRAQQHYPVSAGYTKLVGNDVARFINWMEEEFNYPLDNVHLLGYSLGAHAAGVAGSLTNKKVNRITGLDPAGPNFEYAEAPSRLSPDDADFVDVLHTFTRGSPGRSIGIQKPVGHVDIYPNGGTFQPGCNIGEAIRVIAERGLGDVDQLVKCSHERSIHLFIDSLLNEENPSKAYRCNSKEAFEKGLCLSCRKNRCNNLGYEINKVRAKRSSKMYLKTRSQMPYKVFHYQVKIHFSGTEDGKQHNQAFEISLYGTVAESENIPFTLPEVSTNKTYSFLIYTEVDIGELLMMKLKWISDSYFSWPDWWSSPSFVIERIRVKAGETQKKVIFCAREKVSHLQKGKDSAVFVKCHDKSLKKSG", "length": 474 }, "evidence": [ { "id": "HGNC:6677", "url": "https://alliancegenome.org/gene/HGNC:6677#orthology", "database": "AGR" }, { "id": "MGI:96820", "url": "https://alliancegenome.org/gene/MGI:96820#orthology", "database": "AGR" }, { "id": "RGD:3017", "url": "https://alliancegenome.org/gene/RGD:3017#orthology", "database": "AGR" }, { "id": "FB:FBgn0265267", "url": "https://alliancegenome.org/gene/FB:FBgn0265267#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P27656-1", "protein_name": "Hepatic triacylglycerol lipase", "gene_name": "Lipc", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGNPLQISIFLVFCIFIQSSACGQGVGTEPFGRSLGATEASKPLKKPETRFLLFQDENDRLGCRLRPQHPETLQECGFNSSQPLIMIIHGWSVDGLLENWIWKIVSALKSRQSQPVNVGLVDWISLAYQHYTIAVQNTRIVGQDVAALLLWLEESAKFSRSKVHLIGYSLGAHVSGFAGSSMDGKNKIGRITGLDPAGPMFEGTSPNERLSPDDANFVDAIHTFTREHMGLSVGIKQPIAHYDFYPNGGSFQPGCHFLELYKHIAEHGLNAITQTIKCAHERSVHLFIDSLQHSDLQSIGFQCSDMGSFSQGLCLSCKKGRCNTLGYDIRKDRSGKSKRLFLITRAQSPFKVYHYQFKIQFINQIEKPVEPTFTMSLLGTKEEIKRIPITLGEGITSNKTYSFLITLDKDIGELILLKFKWENSAVWANVWNTVQTIMLWGIEPHHSGLILKTIWVKAGETQQRMTFCPENLDDLQLHPSQEKVFVNCEVKSKRLTESKEQMSQETHAKK", "length": 510 }, "evidence": [ { "id": "HGNC:6619", "url": "https://alliancegenome.org/gene/HGNC:6619#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q06000-1", "protein_name": "Lipoprotein lipase", "gene_name": "Lpl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESKALLLVALGVWLQSLTAFRGGVAAADGGRDFSDIESKFALRTPEDTAEDTCHLIPGLADSVSNCHFNHSSKTFVVIHGWTVTGMYESWVPKLVAALYKREPDSNVIVVDWLYRAQQHYPVSAGYTKLVGNDVARFINWLEEEFNYPLDNVHLLGYSLGAHAAGVAGSLTNKKVNRITGLDPAGPNFEYAEAPSRLSPDDADFVDVLHTFTRGSPGRSIGIQKPVGHVDIYPNGGTFQPGCNIGEAIRVIAEKGLGDVDQLVKCSHERSIHLFIDSLLNEENPSKAYRCNSKEAFEKGLCLSCRKNRCNNVGYEINKVRAKRSSKMYLKTRSQMPYKVFHYQVKIHFSGTENDKQNNQAFEISLYGTVAESENIPFTLPEVATNKTYSFLIYTEVDIGELLMMKLKWKNDSYFRWSDWWSSPSFVIEKIRVKAGETQKKVIFCAREKVSHLQKGKDAAVFVKCHDKSLKKSG", "length": 474 }, "evidence": [ { "id": "HGNC:6677", "url": "https://alliancegenome.org/gene/HGNC:6677#orthology", "database": "AGR" }, { "id": "MGI:96820", "url": "https://alliancegenome.org/gene/MGI:96820#orthology", "database": "AGR" }, { "id": "RGD:3017", "url": "https://alliancegenome.org/gene/RGD:3017#orthology", "database": "AGR" }, { "id": "FB:FBgn0265267", "url": "https://alliancegenome.org/gene/FB:FBgn0265267#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8VBX1-1", "protein_name": "Endothelial lipase", "gene_name": "Lipg", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRDPVFLLGFWSLYCCFPAGSLTTLRPQGSLRDEHHKPTGVPVTITTKPSVTFNIRTSKDPEHEGCNLSLGDSKLLENCGFNMTAKTFFIIHGWTMSGMFESWLHKLVSALQTREKEANVVVVDWLPLAHQLYIDAVSNTRVVGRRVAGMLNWLQEKGEFSLGDVHLIGYSLGAHVAGYAGNFVKGTVGRITGLDPAGPMFEGVDINRRLSPDDADFVDVLHTYTLSFGLSIGIRMPVGHIDIYPNGGDFQPGCGFNDVMGSFAYGTISEMVKCEHERAVHLFVDSLVNQDKPSFAFQCTDPNRFKRGICLSCRKNRCNNIGYNAKKMRKKRNSKMYLKTRAGMPFRVYHYQLKVHMFSYKNSGDIQPDLYITLYGSNADSQNLPLEIVEKIELNATNTFLVYTEEYLGDLFKIRLTWEGVSSSWYNLWNEFRSYLSQPSSPSRELHIRRIRVKSGETQRKVAFCVQDPMKNSISPGQELWFYKCQNDCRVKN", "length": 493 }, "evidence": [ { "id": "HGNC:6623", "url": "https://alliancegenome.org/gene/HGNC:6623#orthology", "database": "AGR" }, { "id": "RGD:1310740", "url": "https://alliancegenome.org/gene/RGD:1310740#orthology", "database": "AGR" }, { "id": "FB:FBgn0265267", "url": "https://alliancegenome.org/gene/FB:FBgn0265267#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9VJH1-1", "protein_name": "Lipase domain-containing protein", "gene_name": "Dmel\\CG13282", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MHWRLVIGLLLLASFNRETIGKRFLNLKPIPIQHEDESSTEGSTNPTPTSTTTPSNRDITIGPCKWAIGRSCPDPDVKYYIYTRHNPMDRQCLHIDESLEKSNLTDSYFNPRYPTKIIIHGYNSDMFLHPLQQMREEYLAKADYNIIYVDWSILSPGPCYISAVHNTKHAGTCTAQLVERLVETGNTDIHVIGFSLGAQVPNYIARNLSSFMLPRITGLDPAMPLFITSGKADKLDPSDASYVDVIHTNALVQGKMERCGHADFYMNGGIMQPGCNGQKINSFACSHQRAPAYFLESIRSPKGFWGWACSGYISYLLGMCPPTNFLLEAGENIRPTTRGMFMIDTNDSSPFALGKWTDLPTLGAKQPQWRVPTQKLKAPPNQGVDPLLHHIDQFGKLAANFNNLQMWPTEQDPYEHWTSFSPEQKENDSDGDSVEEQDPVEFIEPDDRQMISTEARPTQSWWDYRRNLTYGFMEDNIFSVPTVD", "length": 484 }, "evidence": [ { "id": "HGNC:6619", "url": "https://alliancegenome.org/gene/HGNC:6619#orthology", "database": "AGR" }, { "id": "HGNC:6623", "url": "https://alliancegenome.org/gene/HGNC:6623#orthology", "database": "AGR" }, { "id": "HGNC:6677", "url": "https://alliancegenome.org/gene/HGNC:6677#orthology", "database": "AGR" }, { "id": "MGI:96820", "url": "https://alliancegenome.org/gene/MGI:96820#orthology", "database": "AGR" }, { "id": "RGD:1310740", "url": "https://alliancegenome.org/gene/RGD:1310740#orthology", "database": "AGR" }, { "id": "RGD:3017", "url": "https://alliancegenome.org/gene/RGD:3017#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VQC2-1", "protein_name": "Lipase domain-containing protein", "gene_name": "Dmel\\CG18641", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MWLQCARKPIRADFWLQLLCVSFTLFHLEFAAAQNAGVVAAAVAAGQNQTQVYVTDSCLQKPYRCPHPKIQFYLYTRRTQEQPEFIDVLDPNALYYTHFNPRHPTKIIIHGFGGGRTLSPSPDLREAYFSVGEYNIIIVDYADAVKEPCLSQMDWAPRFGSLCISQLVKYLARHPRGVQPDDLHFIGYSVGAHIAGLVANYLKPEEGKLGRITALDPTIFFYAGANNSRDLDSTDAHFVDVLHTGAGILGQWHSSGHADFYVNGGTRQPACVGSATLFQTLACDHTKVTPYFIESITTTRGFYAGPCPNLFSYLIGWCEPKDSEYVLMGEHCSHKARGNYYVTTNAKAPFARGFPGKGRSNGEYQGVRR", "length": 369 }, "evidence": [ { "id": "HGNC:6619", "url": "https://alliancegenome.org/gene/HGNC:6619#orthology", "database": "AGR" }, { "id": "HGNC:6623", "url": "https://alliancegenome.org/gene/HGNC:6623#orthology", "database": "AGR" }, { "id": "HGNC:6677", "url": "https://alliancegenome.org/gene/HGNC:6677#orthology", "database": "AGR" }, { "id": "MGI:96820", "url": "https://alliancegenome.org/gene/MGI:96820#orthology", "database": "AGR" }, { "id": "RGD:1310740", "url": "https://alliancegenome.org/gene/RGD:1310740#orthology", "database": "AGR" }, { "id": "RGD:3017", "url": "https://alliancegenome.org/gene/RGD:3017#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VRW5-1", "protein_name": "Lipase domain-containing protein", "gene_name": "Dmel\\CG10163", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRAQFTMQKSTAQMIIAVCLICQSLAVEDKDKATNPLNIDSVQKHNVKLLSEQLNRGWRAFCDAPVDEGVMSLFQGINPSDARLHVMTITNQSVELPIKSISQIKDFDINPERKTLIYVNAFHTADSYFSVQEHLTLLQNSRRDLNVIVVDFAKDVAQLYYAVRHHLSVNGYFVYKLLRALKDAGIAVQDITLAGHSVGANIAALGAQLFAKENKQLVGQLLAIDPATMCRTTDILVKQSVALRVVVLHGEGDVFGVRVPLGHIDIYPNGIGYFPRRKLQPGCESKICSHMYPFILFMEALIEGVMIPATKCESWAKFRQGDCNFQNTINIGLIYPANAKGLYFCMTQPNPPFTYMEHGLRYKARRPEKSSEKNRIKF", "length": 378 }, "evidence": [ { "id": "HGNC:6619", "url": "https://alliancegenome.org/gene/HGNC:6619#orthology", "database": "AGR" }, { "id": "HGNC:6623", "url": "https://alliancegenome.org/gene/HGNC:6623#orthology", "database": "AGR" }, { "id": "HGNC:6677", "url": "https://alliancegenome.org/gene/HGNC:6677#orthology", "database": "AGR" }, { "id": "MGI:96820", "url": "https://alliancegenome.org/gene/MGI:96820#orthology", "database": "AGR" }, { "id": "RGD:1310740", "url": "https://alliancegenome.org/gene/RGD:1310740#orthology", "database": "AGR" }, { "id": "RGD:3017", "url": "https://alliancegenome.org/gene/RGD:3017#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VU78-1", "protein_name": "Lipase domain-containing protein", "gene_name": "Dmel\\CG10116", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MQTGVQLALFLTLTIAAVYGETGFFLNTRRVQENAQPIEAEVEALVRSSFYAADPTVVTIPRWLGNISSPEIPAVVSARLQQQDSNIISVDLSEANDETEIIDSVASLVIVLHNQFDMPLDRILVVGFAEGAHLAGGVAAKVQQDLGRQLSQITALDPSSGAELDHKLSQADAEFVEVVHTNAGGEGTWERLGHVDYYPNGGQTQPGCTTDSCSHERAFELLAEMWSPENDFVSARCGSVETLSASSCRWSTHKMGQKQEEEQPASGIYFLETRQSSPFSRGAYFISFL", "length": 289 }, "evidence": [ { "id": "HGNC:6619", "url": "https://alliancegenome.org/gene/HGNC:6619#orthology", "database": "AGR" }, { "id": "HGNC:6623", "url": "https://alliancegenome.org/gene/HGNC:6623#orthology", "database": "AGR" }, { "id": "HGNC:6677", "url": "https://alliancegenome.org/gene/HGNC:6677#orthology", "database": "AGR" }, { "id": "MGI:96820", "url": "https://alliancegenome.org/gene/MGI:96820#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VX69-1", "protein_name": "Lipase domain-containing protein", "gene_name": "Dmel\\CG5162", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGRVPAKMHTLLALLLQLLVASIHAIEWSLPDVINSIGNVGTSIVDPSLLPTPQGLLEGSKQLIAGYPFEFVSNSLNVICSQALASNKIKSKYSPDINKMNFQLQTACEKKNFPLTSPESMWKSPLFDVKKKVVILATGWTTTVNGSDTIEVFSKAYNCRGDVNFVAVDAARFVDTLYTWSAFNTEEIGENIALGLVKLLDLVPVENIHLIGHSLGAHIVGSAGRHLQHLTNQTIPRITGLDPAKPCFNEGEALSGLMRGDAHFVDVIHSNPGVLGKRDPVGDVDFYPGGMSPLAAGCFSVTCAHARSWEYFAETVFPGNERNFMATRCNSISKLRDFRCPGDEVPMGYAVPQNIKGNYFLEVSASAPFGMHASVVRSAHLEHCGLCPESTSTTEVPSTTTTGKPGSWFSG", "length": 411 }, "evidence": [ { "id": "HGNC:6619", "url": "https://alliancegenome.org/gene/HGNC:6619#orthology", "database": "AGR" }, { "id": "HGNC:6623", "url": "https://alliancegenome.org/gene/HGNC:6623#orthology", "database": "AGR" }, { "id": "HGNC:6677", "url": "https://alliancegenome.org/gene/HGNC:6677#orthology", "database": "AGR" }, { "id": "MGI:96820", "url": "https://alliancegenome.org/gene/MGI:96820#orthology", "database": "AGR" }, { "id": "RGD:1310740", "url": "https://alliancegenome.org/gene/RGD:1310740#orthology", "database": "AGR" }, { "id": "RGD:3017", "url": "https://alliancegenome.org/gene/RGD:3017#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9WVG5-1", "protein_name": "Endothelial lipase", "gene_name": "Lipg", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRNTVFLLGFWSVYCYFPAGSITTLRPQGSLRDEHHKPTGVPATARPSVAFNIRTSKDPEQEGCNLSLGDSKLLENCGFNMTAKTFFIIHGWTMSGMFESWLHKLVSALQMREKDANVVVVDWLPLAHQLYTDAVNNTRVVGQRVAGMLDWLQEKEEFSLGNVHLIGYSLGAHVAGYAGNFVKGTVGRITGLDPAGPMFEGVDINRRLSPDDADFVDVLHTYTLSFGLSIGIRMPVGHIDIYPNGGDFQPGCGFNDVIGSFAYGTISEMVKCEHERAVHLFVDSLVNQDKPSFAFQCTDSSRFKRGICLSCRKNRCNNIGYNAKKMRKKRNSKMYLKTRAGMPFKVYHYQLKVHMFSYNNSGDTQPTLYITLYGSNADSQNLPLEIVEKIELNATNTFLVYTEEDLGDLLKMRLTWEGVAHSWYNLWNEFRNYLSQPSNPSRELYIRRIRVKSGETQRKVTFCTQDPTKSSISPGQELWFHKCQDGWKMKNKTSPFVNLA", "length": 500 }, "evidence": [ { "id": "HGNC:6623", "url": "https://alliancegenome.org/gene/HGNC:6623#orthology", "database": "AGR" }, { "id": "RGD:1310740", "url": "https://alliancegenome.org/gene/RGD:1310740#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y5X9-1", "protein_name": "Endothelial lipase", "gene_name": "LIPG", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSNSVPLLCFWSLCYCFAAGSPVPFGPEGRLEDKLHKPKATQTEVKPSVRFNLRTSKDPEHEGCYLSVGHSQPLEDCSFNMTAKTFFIIHGWTMSGIFENWLHKLVSALHTREKDANVVVVDWLPLAHQLYTDAVNNTRVVGHSIARMLDWLQEKDDFSLGNVHLIGYSLGAHVAGYAGNFVKGTVGRITGLDPAGPMFEGADIHKRLSPDDADFVDVLHTYTRSFGLSIGIQMPVGHIDIYPNGGDFQPGCGLNDVLGSIAYGTITEVVKCEHERAVHLFVDSLVNQDKPSFAFQCTDSNRFKKGICLSCRKNRCNSIGYNAKKMRNKRNSKMYLKTRAGMPFRVYHYQMKIHVFSYKNMGEIEPTFYVTLYGTNADSQTLPLEIVERIEQNATNTFLVYTEEDLGDLLKIQLTWEGASQSWYNLWKEFRSYLSQPRNPGRELNIRRIRVKSGETQRKLTFCTEDPENTSISPGRELWFRKCRDGWRMKNETSPTVELP", "length": 500 }, "evidence": [ { "id": "HGNC:6623", "url": "https://alliancegenome.org/gene/HGNC:6623#orthology", "database": "AGR" }, { "id": "RGD:1310740", "url": "https://alliancegenome.org/gene/RGD:1310740#orthology", "database": "AGR" }, { "id": "FB:FBgn0265267", "url": "https://alliancegenome.org/gene/FB:FBgn0265267#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VX70", "url": "https://www.uniprot.org/uniprotkb/Q9VX70" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "lipase activity", "id": "GO:0016298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016298", "evidence": [ { "database": "UniProtKB", "id": "Q9VX70", "url": "https://www.uniprot.org/uniprotkb/Q9VX70" } ], "pmid": "" }, { "name": "serine hydrolase activity", "id": "GO:0017171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017171", "evidence": [ { "database": "UniProtKB", "id": "Q9VX70", "url": "https://www.uniprot.org/uniprotkb/Q9VX70" } ], "pmid": "" }, { "name": "triacylglycerol lipase activity", "id": "GO:0004806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004806", "evidence": [ { "database": "UniProtKB", "id": "Q9VX70", "url": "https://www.uniprot.org/uniprotkb/Q9VX70" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "Q9VX70", "url": "https://www.uniprot.org/uniprotkb/Q9VX70" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 184, "end_pos": 186, "annotation": "n_glycosylation_sequon" }, { "start_pos": 197, "end_pos": 199, "annotation": "n_glycosylation_sequon" }, { "start_pos": 219, "end_pos": 221, "annotation": "n_glycosylation_sequon" }, { "start_pos": 234, "end_pos": 236, "annotation": "n_glycosylation_sequon" }, { "start_pos": 273, "end_pos": 275, "annotation": "n_glycosylation_sequon" }, { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VX70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VX70" }, { "id": "PF00151", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00151" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Lipase", "eco_id": "ECO_0000259", "start_pos": 171, "end_pos": 431, "start_aa": "Arg", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 184, "end_pos": 186 }, { "start_pos": 197, "end_pos": 199 }, { "start_pos": 219, "end_pos": 221 }, { "start_pos": 234, "end_pos": 236 }, { "start_pos": 273, "end_pos": 275 }, { "start_pos": 85, "end_pos": 87 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, 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melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VX85", "url": "https://www.uniprot.org/uniprotkb/Q9VX85" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VX85", "url": "https://www.uniprot.org/uniprotkb/Q9VX85" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VX85", "url": "https://www.uniprot.org/uniprotkb/Q9VX85" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VX85", "url": "https://www.uniprot.org/uniprotkb/Q9VX85" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VX85", "url": "https://www.uniprot.org/uniprotkb/Q9VX85" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VX85", "url": "https://www.uniprot.org/uniprotkb/Q9VX85" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VX85", "url": "https://www.uniprot.org/uniprotkb/Q9VX85" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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SV=2 CANONICAL=Q9VXA9-1" }, "isoforms": [ { "isoform_ac": "Q9VXA9-1", "url": "https://www.uniprot.org/uniprotkb/Q9VXA9/entry#Q9VXA9-1", "sequence": { "sequence": "MAMNNRVRIVVVGDSGVGKTSLTHLITHNEALIRPGWTVGCNIQVKMHPFREGTARECPYFVELFDVGGSLNHKNTRSVFYAGIDGIILVHDLTNAKSQRQLIDWLYEIVNKEGKDTNKSNGASMPPSPPSPLSSFSTDNLGTDGHILFDMEEFLGATQTPILVMGTKLDLLDEKRHPKMGVKKPGGIADKCGAEEIWLNCRNSRSLAAGTTDAVKLSRFFDRVIENRKALRAALAFGVSSSNAVSPPDRRRFGPTSAKMEDSVLPLLDTQDLK", "length": 274, "header": "tr|Q9VXA9-1|Q9VXA9_DROME Isoform 1 of Rab-like protein 3 OS=Drosophila melanogaster OX=7227 GN=Q9VXA9 PE=4 SV=2 CANONICAL=Q9VXA9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, 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{ "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VXA9", "url": "https://www.uniprot.org/uniprotkb/Q9VXA9" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXA9", "url": "https://www.uniprot.org/uniprotkb/Q9VXA9" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXA9", "url": "https://www.uniprot.org/uniprotkb/Q9VXA9" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VXA9", "url": "https://www.uniprot.org/uniprotkb/Q9VXA9" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VXA9", "url": "https://www.uniprot.org/uniprotkb/Q9VXA9" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VXA9", "url": "https://www.uniprot.org/uniprotkb/Q9VXA9" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXA9", "url": "https://www.uniprot.org/uniprotkb/Q9VXA9" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXA9", "url": "https://www.uniprot.org/uniprotkb/Q9VXA9" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"ZFIN:ZDB-GENE-040808-11", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040808-11#orthology", "database": "AGR" }, { "id": "MGI:1914907", "url": "https://alliancegenome.org/gene/MGI:1914907#orthology", "database": "AGR" }, { "id": "RGD:1306436", "url": "https://alliancegenome.org/gene/RGD:1306436#orthology", "database": "AGR" }, { "id": "FB:FBgn0030792", "url": "https://alliancegenome.org/gene/FB:FBgn0030792#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9D4V7-1", "protein_name": "Rab-like protein 3", "gene_name": "Rabl3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASLDRVKVLVLGDSGVGKSSLVHLLCHNQVLGNPSWTVGCSVDIRVHDYKEGTPEEKTYYIELWDVGGSVGSASSVKSTRAVFYNSVNGIILVHDLTNKKSSQNLYRWSLEVLNRDAVPTGVLVTNGDYDREQFADNQIPLLVIGTKLDQIHETKRHEVLIRTAFLAEDFNAEEINLDCTNPRSSAAGSSNAVKLSRFFDKVIEKRYFFREGNQIPGFSDRKRFGGGALKNFHCD", "length": 236 }, "evidence": [ { "id": "HGNC:18072", "url": 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"https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "Q9VXA9", "url": "https://www.uniprot.org/uniprotkb/Q9VXA9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "Q9VXA9", "url": "https://www.uniprot.org/uniprotkb/Q9VXA9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "Q9VXA9", "url": "https://www.uniprot.org/uniprotkb/Q9VXA9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 118, "end_pos": 120, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], 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"recommended", "evidence": [ { "id": "Q9VXB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXB4" } ] }, { "name": "CG9609", "type": "synonym", "evidence": [ { "id": "NP_573161", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573161" }, { "id": "Q9VXB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXB4" } ] }, { "name": "Dmel\\CG9609", "type": "synonym", "evidence": [ { "id": "NP_573161", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573161" } ] }, { "name": "Dmel_CG9609", "type": "synonym", "evidence": [ { "id": "Q9VXB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXB4" } ] } ], "protein_names": [ { "name": "C2H2-type domain-containing protein", "type": "recommended", "evidence": [ { "id": "Q9VXB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXB4/entry#names_and_taxonomy" } ] }, { "name": "CG9609-PA", "type": "synonym", "evidence": [ { "id": "NP_573161", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573161" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_573161", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573161" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VXB4", "url": "https://www.uniprot.org/uniprotkb/Q9VXB4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG9609", "url": "https://www.uniprot.org/uniprotkb/Q9VXB4", "locus": { "chromosome": "X", "start_pos": 16785115, "end_pos": 16787008, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0030787", "url": "https://www.ensemblgenomes.org/id/FBgn0030787" } ] } } ], "crossref": [ { "id": "FB:FBgn0030787", "url": "https://alliancegenome.org/gene/FB:FBgn0030787", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0030787", "url": "https://bgee.org/?page=gene&gene_id=FBgn0030787", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0030787", "url": "https://flybase.org/reports/FBgn0030787", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "32663", "url": "https://www.ncbi.nlm.nih.gov/gene/32663", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041697", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041697", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051061", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051061", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG9609", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG9609", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YTKHCRD", "url": "https://omabrowser.org/oma/group/YTKHCRD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VXB4", "url": "https://www.orthodb.org/?gene=Q9VXB4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46179", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46179", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46179:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46179:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_573161", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573161", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VXB4", "url": "https://www.uniprot.org/uniprotkb/Q9VXB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VXB4-1", "url": "https://www.uniprot.org/uniprotkb/Q9VXB4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPPGTQIASDSDMETALEEFKQRQGRRNSIGSAKYACSMPKCEATFKRLDQLDRHEYHHTGIKKHACSYEGCDKTYSIVTHLKRHLRSTHERPESAAKKTVKCALEECSKMFISVSNMTRHMRETHESPKVYPCSQCSAKFSQKLKLKRHEIREHTLEYPYSCSKCSRGFYQQWQCQSHEPSCKLYECPGCPLQFDKWTLYTKHCRDSLHGKNRHKCDRCDSAFDKPSELKRHLEVKHKEAAQTDECATSFTCNEEGCGKSYSYLRNLRQHMLTAHSGRRFECQALDCGRCFSSAQNLARHLLRDHKDGATKKELKAKKKDKSKTGEGGKTKSTSRKRRRDAGRSKHSRLSKLACLQLDKEDDEAVRERQPLVLEKITQSLKDDPVEELLAQTLQDEEEKEQE", "length": 403, "header": "tr|Q9VXB4-1|Q9VXB4_DROME Isoform 1 of C2H2-type domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG9609 PE=1 SV=1 CANONICAL=Q9VXB4-1" }, "isoforms": [ { "isoform_ac": "Q9VXB4-1", "url": "https://www.uniprot.org/uniprotkb/Q9VXB4/entry#Q9VXB4-1", "sequence": { "sequence": "MPPGTQIASDSDMETALEEFKQRQGRRNSIGSAKYACSMPKCEATFKRLDQLDRHEYHHTGIKKHACSYEGCDKTYSIVTHLKRHLRSTHERPESAAKKTVKCALEECSKMFISVSNMTRHMRETHESPKVYPCSQCSAKFSQKLKLKRHEIREHTLEYPYSCSKCSRGFYQQWQCQSHEPSCKLYECPGCPLQFDKWTLYTKHCRDSLHGKNRHKCDRCDSAFDKPSELKRHLEVKHKEAAQTDECATSFTCNEEGCGKSYSYLRNLRQHMLTAHSGRRFECQALDCGRCFSSAQNLARHLLRDHKDGATKKELKAKKKDKSKTGEGGKTKSTSRKRRRDAGRSKHSRLSKLACLQLDKEDDEAVRERQPLVLEKITQSLKDDPVEELLAQTLQDEEEKEQE", "length": 403, "header": "tr|Q9VXB4-1|Q9VXB4_DROME Isoform 1 of C2H2-type domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG9609 PE=1 SV=1 CANONICAL=Q9VXB4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VXB4", "url": "https://www.uniprot.org/uniprotkb/Q9VXB4" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VXB4", "url": "https://www.uniprot.org/uniprotkb/Q9VXB4" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXB4", "url": "https://www.uniprot.org/uniprotkb/Q9VXB4" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXB4", "url": "https://www.uniprot.org/uniprotkb/Q9VXB4" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VXB4", "url": "https://www.uniprot.org/uniprotkb/Q9VXB4" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VXB4", "url": "https://www.uniprot.org/uniprotkb/Q9VXB4" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VXB4", "url": "https://www.uniprot.org/uniprotkb/Q9VXB4" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXB4", "url": "https://www.uniprot.org/uniprotkb/Q9VXB4" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXB4", "url": "https://www.uniprot.org/uniprotkb/Q9VXB4" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VXB4", "url": "https://www.uniprot.org/uniprotkb/Q9VXB4" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VXB4", "url": "https://www.uniprot.org/uniprotkb/Q9VXB4" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], 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16726948, "end_pos": 16721183, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0052572", "url": "https://www.ensemblgenomes.org/id/FBgn0052572" } ] } } ], "crossref": [ { "id": "FB:FBgn0052572", "url": "https://alliancegenome.org/gene/FB:FBgn0052572", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0052572", "url": "https://bgee.org/?page=gene&gene_id=FBgn0052572", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0052572", "url": "https://flybase.org/reports/FBgn0052572", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "32657", "url": "https://www.ncbi.nlm.nih.gov/gene/32657", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dme:Dmel_CG32572", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG32572", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WAGHRYL", "url": "https://omabrowser.org/oma/group/WAGHRYL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VXB8", "url": "https://www.orthodb.org/?gene=Q9VXB8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "NP_728015", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_728015", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VXB8", "url": "https://www.uniprot.org/uniprotkb/Q9VXB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VXB8-1", "url": "https://www.uniprot.org/uniprotkb/Q9VXB8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELDMDMTGPEQLLPSLPASSTRQLVRRRTGHAAESSRVQRCRTTITAHAHAPATQSASTGKRSRLPASSSGNIAVVRPGSNDNRVRQDRKNPRESSVRPTRQVLSARVLAHSNPYTVKQPPKERRSGTQRTRNQQHPTLATSRSGFGGHCTGPPAPATLRRAAPLPPASQMRPCLRSVRAKVDSHLCPHLSNRQRPTPKNPEHAQPSSQRSCQSTKGKSLAAAHQQLELMLSKIERVTDYQPPPTPAAQFKRRGSGVKVAKGVSRQMAHPPPVPAGTPMLSARRNKNIAMRTDGGGGAELEEDRNGDGEGDGFGHGEGDHIDTAIPLVQNPQCLPPAKRDALMQLLQRTEQHDKGIVDMVATTGDSNRDAMLMLLQMMPLSLSDSPYKKKILDGHRHLKERQKQQQKLRPGGNEGFKEVKDLHGPDGQERYHNVRNALEHRSDSHPLTERQEQAMLERAQLERDKQLVINCREKRRLKEQIGEQPPPQDSNHTKNPTTPPRSTDPWKQVLQDRDRFRANCNRSCFYNNSQSSALWKIYAKVASKLSSQLIESVDVEFHRSVINYINDIVGHKVN", "length": 575, "header": "tr|Q9VXB8-1|Q9VXB8_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=CG13007 PE=4 SV=2 CANONICAL=Q9VXB8-1" }, "isoforms": [ { "isoform_ac": "Q9VXB8-1", "url": "https://www.uniprot.org/uniprotkb/Q9VXB8/entry#Q9VXB8-1", "sequence": { "sequence": "MELDMDMTGPEQLLPSLPASSTRQLVRRRTGHAAESSRVQRCRTTITAHAHAPATQSASTGKRSRLPASSSGNIAVVRPGSNDNRVRQDRKNPRESSVRPTRQVLSARVLAHSNPYTVKQPPKERRSGTQRTRNQQHPTLATSRSGFGGHCTGPPAPATLRRAAPLPPASQMRPCLRSVRAKVDSHLCPHLSNRQRPTPKNPEHAQPSSQRSCQSTKGKSLAAAHQQLELMLSKIERVTDYQPPPTPAAQFKRRGSGVKVAKGVSRQMAHPPPVPAGTPMLSARRNKNIAMRTDGGGGAELEEDRNGDGEGDGFGHGEGDHIDTAIPLVQNPQCLPPAKRDALMQLLQRTEQHDKGIVDMVATTGDSNRDAMLMLLQMMPLSLSDSPYKKKILDGHRHLKERQKQQQKLRPGGNEGFKEVKDLHGPDGQERYHNVRNALEHRSDSHPLTERQEQAMLERAQLERDKQLVINCREKRRLKEQIGEQPPPQDSNHTKNPTTPPRSTDPWKQVLQDRDRFRANCNRSCFYNNSQSSALWKIYAKVASKLSSQLIESVDVEFHRSVINYINDIVGHKVN", "length": 575, "header": "tr|Q9VXB8-1|Q9VXB8_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=CG13007 PE=4 SV=2 CANONICAL=Q9VXB8-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { 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D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VXB8", "url": "https://www.uniprot.org/uniprotkb/Q9VXB8" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VXB8", "url": "https://www.uniprot.org/uniprotkb/Q9VXB8" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXB8", "url": "https://www.uniprot.org/uniprotkb/Q9VXB8" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXB8", "url": "https://www.uniprot.org/uniprotkb/Q9VXB8" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VXB8", "url": "https://www.uniprot.org/uniprotkb/Q9VXB8" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VXB8", "url": "https://www.uniprot.org/uniprotkb/Q9VXB8" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VXB8", "url": "https://www.uniprot.org/uniprotkb/Q9VXB8" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXB8", "url": "https://www.uniprot.org/uniprotkb/Q9VXB8" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXB8", "url": "https://www.uniprot.org/uniprotkb/Q9VXB8" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"pathway": [ { "id": "dme:Dmel_CG32572", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG32572", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 492, "end_pos": 494, "annotation": "n_glycosylation_sequon" }, { "start_pos": 522, "end_pos": 524, "annotation": "n_glycosylation_sequon" }, { "start_pos": 528, "end_pos": 530, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 246 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 492, "end_pos": 494 }, { "start_pos": 522, "end_pos": 524 }, { 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"url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VXC5", "url": "https://www.uniprot.org/uniprotkb/Q9VXC5" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VXC5", "url": "https://www.uniprot.org/uniprotkb/Q9VXC5" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXC5", "url": "https://www.uniprot.org/uniprotkb/Q9VXC5" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXC5", "url": "https://www.uniprot.org/uniprotkb/Q9VXC5" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VXC5", "url": "https://www.uniprot.org/uniprotkb/Q9VXC5" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VXC5", "url": "https://www.uniprot.org/uniprotkb/Q9VXC5" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VXC5", "url": "https://www.uniprot.org/uniprotkb/Q9VXC5" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXC5", "url": "https://www.uniprot.org/uniprotkb/Q9VXC5" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXC5", "url": "https://www.uniprot.org/uniprotkb/Q9VXC5" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"id": "Q9VXC8-1", "url": "https://www.uniprot.org/uniprotkb/Q9VXC8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMQPRLVILGLIGLTAVGMCHAQGRIMGGEDADATATTFTASLRVDNAHVCGGSILSQTKILTTAHCVHRDGKLIDASRLACRVGSTNQYAGGKIVNVESVAVHPDYYNLNNNLAVITLSSELTYTDRITAIPLVASGEALPAEGSEVIVAGWGRTSDGTNSYKIRQISLKVAPEATCLDAYSDHDEQSFCLAHELKEGTCHGDGGGGAIYGNTLIGLTNFVVGACGSRYPDVFVRLSSYADWIQEQIA", "length": 249, "header": "tr|Q9VXC8-1|Q9VXC8_DROME Isoform 1 of trypsin OS=Drosophila melanogaster OX=7227 GN=sphe PE=1 SV=2 CANONICAL=Q9VXC8-1" }, "isoforms": [ { "isoform_ac": "Q9VXC8-1", "url": "https://www.uniprot.org/uniprotkb/Q9VXC8/entry#Q9VXC8-1", "sequence": { "sequence": "MMQPRLVILGLIGLTAVGMCHAQGRIMGGEDADATATTFTASLRVDNAHVCGGSILSQTKILTTAHCVHRDGKLIDASRLACRVGSTNQYAGGKIVNVESVAVHPDYYNLNNNLAVITLSSELTYTDRITAIPLVASGEALPAEGSEVIVAGWGRTSDGTNSYKIRQISLKVAPEATCLDAYSDHDEQSFCLAHELKEGTCHGDGGGGAIYGNTLIGLTNFVVGACGSRYPDVFVRLSSYADWIQEQIA", "length": 249, "header": "tr|Q9VXC8-1|Q9VXC8_DROME Isoform 1 of trypsin OS=Drosophila melanogaster OX=7227 GN=sphe PE=1 SV=2 CANONICAL=Q9VXC8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VXC8", "url": "https://www.uniprot.org/uniprotkb/Q9VXC8" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VXC8", "url": "https://www.uniprot.org/uniprotkb/Q9VXC8" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXC8", "url": "https://www.uniprot.org/uniprotkb/Q9VXC8" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXC8", "url": "https://www.uniprot.org/uniprotkb/Q9VXC8" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VXC8", "url": "https://www.uniprot.org/uniprotkb/Q9VXC8" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VXC8", "url": "https://www.uniprot.org/uniprotkb/Q9VXC8" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VXC8", "url": "https://www.uniprot.org/uniprotkb/Q9VXC8" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXC8", "url": "https://www.uniprot.org/uniprotkb/Q9VXC8" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXC8", "url": "https://www.uniprot.org/uniprotkb/Q9VXC8" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VXC8", "url": "https://www.uniprot.org/uniprotkb/Q9VXC8" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VXC8", "url": "https://www.uniprot.org/uniprotkb/Q9VXC8" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG9675", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG9675", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1PUX6-1", "protein_name": "trypsin", "gene_name": "gzm3.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MQYIMLLCVFLLLSLFSLSGGLESGIVGGREAKHHSRPYMASLQKKRNHVCGGMLIKEDYVLTSAHCWNETDKYSLQIVLGAHNISQKENSQQIIQVEKYIKHRKFDIMLLKLRTKAVLNHFVDIINLPKHEISILAPLECSIAGWGMKRPGEGASNVLRVVNLQLESNAKCKSKWQTHFNFKNMVCTVSDGKKAFCQGDSGSPLLCNSELYGMAAYTYPKNCTFKEYPEVYMKVSAFLPWIKKNIQ", "length": 247 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-133", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-133#orthology", "database": "AGR" }, { "id": "FB:FBgn0030774", "url": "https://alliancegenome.org/gene/FB:FBgn0030774#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABK0L7U4-1", "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "LOC100361261", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKLLLLLQSFSLAPKTDAGEIIGGHEAKPHSRPYMAYLQIMDENSGNKTCGGFLIREYFVLTAAHWAHNIKEQEKKQQVIPMVKIIPHPAYNAKTISNDLMLLKLKIKAKKTSAVKTLNLPRSNVKVKPGDVCYVAGWGKLGPMGKFPDTLQEVELIVQEDQKCESYLTNVYDKANEKCAGEPKIKHASFQGDSGGPLVCKKVAAGIVSYGCKDGSTPRAFTKVSTFLSRIKKTMKKN", "length": 238 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-133", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-133#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LB04-1", "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "Gzmc-ps4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPPVLILLTLFLPLGARADEIIGGNEVSPHSCPYMAYFEDNEKTFGGFLVRDNFMLTAAHCRGRSMTVILGAHNIKAKEKTQQIIPVANTTPHPDYNPDKRSNDIMLLKLVRSAKRTSTVRPLNLPRRNAHVKPGDVCYMAGWGKITPQGEFPNTLREIELTVQKDRACASQFQSSYIKASEICVGDSKIKGPSFEEDSGGPLVYKKAAAGIVSYGKTDASAPQVFTRVLSFLSWIKKTMKNS", "length": 243 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-133", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-133#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LBG7-1", "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "Gzmf", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPPVLILLTLLLPLEAGAEEIIGGHEVKPHSYPYMAFIQSVKADGNISYCGGFLVQDYFVLTAAHCEGESMTVMLGAHNIKAKEDTQQIISVEKAISHPAYNKVDYSYDIMLLKLKSKAKRTKAVSTLMLPQSDAQVKPGDVCHVAGWGLTSINGTKVSSCLREAELIIQEDQECEKIFYNYFKTIQICAGDPNNVQDASKGDSGGPLVCDNRAYGVIAYGKKGEISSGVFTKVVYFLPWISRNMKVL", "length": 248 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-133", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-133#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LHT5-1", "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "Gzmc", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPPVLILLTLFLSHGARAEEIIRGNEVSPHSDPYMAYFEFLNDNEKKTFCGGFLVRDNFVLMAAHCRGRSMTVTLGAYNIKAKEKTQQIIPVANTTPHPAYNPDKRSNDIMLLKLVRSAKRTSNVRPLNQPRSNAHVKTGDVCYMAGWGKITPQGELPNTLREVELTVQKDRVCASQFQSTYIKASEICVGDSKSKGASFEEDSGGPLVYKKAAAGIVSYGKTDGSAPQVFTRVLSFLSWIKKTMKNS", "length": 248 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-133", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-133#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LNJ0-1", "protein_name": "Granzyme B-like 3", "gene_name": "Gzmbl3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "FNLVSLLLQAHLSRWSQHCGIKNIGGHEADPHSRPYMAYLQYKNEDSRDTICGGFLIREDFVLTAAHCSGSKINVTLGAHNIKEREKTQQVIPVVKIIPHPAYNAKTISNDIMLLKLKSKAKRTSTVKPLNLPRSNFKVKPGDVCYVAGWGKLGPMGKFPDTLQEVELTVQEDQECETYLKNAYDKANQICAGDPKIKRASFQGASGGPLVCKKVAAGIVSYGRKDGSTPRAFTKVSTFLSWIEETMKKS", "length": 250 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-133", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-133#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZRW9-1", "protein_name": "Granzyme N", "gene_name": "Gzmn", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPAVLILLTFLLPLGDGAEEVIGGHEVPPHSRPYMALISFLKVDGNRSSCGGFLVRDYFVLTAAHCTGSSMTVILGAHNLHEQEKTQQIIPVEKAIPHLGYNPLNHSNDIMLLKLESKAKRTKAVRTLRLPGRKDHVNPGDVCGVAGWGKTSINANKGSALLEEAELIIQGDAECKKRFRHYSETTEICAGDPNEIEAPSKGDSGAPLVCDNKAYGVLSYVKSKKISSGVFTKVVYFLPWISQNTELL", "length": 248 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-133", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-133#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZY93-1", "protein_name": "Granzyme F like 1", "gene_name": "Gzmfl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPVLILLTFLLPLGAGAEEIIGGHEVKSHSRPYMAFIASTDTNRSKNFCGGFLIQYKFVLTAAHCREISMIVILGAHNISAQERTQQIIPVEKAIPHPAYNPMDHTNDIMLLKLKRKAKKTKSVRILNLPMRHARLKPGVLCHVAGWGLMSLNATKRPALLQEAELIIQEDHECKNVFRHYSETTEICAGDPKKIQDIFQGDSGGPLVCDNKAYGVVSYGKRRRITSGIFTKVVYFLPWISRKMKLL", "length": 248 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-133", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-133#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A488-1", "protein_name": "Elastase, neutrophil expressed", "gene_name": "Elane", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQPTMALHRPSNQTLASMLLALLLVCPALASEIVGGRPAQPHAWPFMVSLQRRGGHFCGATLIARNFVMSAAHCVNGRNFQSVQVVLGAHDLRRREPTRQIFSVQRIFENGFDPSRLLNDIVIIQLNGSATINANVQVAELPAQGQGVGNRTPCVAMGWGRLGTNRPLPSVLQELNVTVVTNLCRRRVNVCTLVPRRQAGICFGDSGGPLVCNNLVQGIDSFIRGGCGSGFYPDAFAPVAEFADWINSIIRSHDDRPLTNPKDREREGRTN", "length": 271 }, "evidence": [ { "id": "RGD:1307968", "url": "https://alliancegenome.org/gene/RGD:1307968#orthology", "database": "AGR" }, { "id": "FB:FBgn0030774", "url": "https://alliancegenome.org/gene/FB:FBgn0030774#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O35164-1", "protein_name": "Mast cell protease 9", "gene_name": "Mcpt9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQALLFLMALLLPSRAGAEEIIGGVESEPHSRPYMAYVNTFSKKGYVAICGGFLIAPQFVMTAAHCSGRRMTVTLGAHNVRKRECTQQKIKVEKYILPPNYNVSSKFNDIVLLKLKKQANLTSAVDVVPLPGPSDFAKPGTMCWAAGWGRTGVKKSISHTLREVELKIVGEKACKIFRHYKDSLQICVGSSTKVASVYMGDSGGPLLCAGVAHGIVSSGRGNAKPPAIFTRISPHVPWINRVIKGE", "length": 246 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-133", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-133#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P00770-1", "protein_name": "Mast cell protease 2", "gene_name": "Mcpt2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQALLFLMALLLPSGAGAEEIIGGVESIPHSRPYMAHLDIVTEKGLRVICGGFLISRQFVLTAAHCKGREITVILGAHDVRKRESTQQKIKVEKQIIHESYNSVPNLHDIMLLKLEKKVELTPAVNVVPLPSPSDFIHPGAMCWAAGWGKTGVRDPTSYTLREVELRIMDEKACVDYRYYEYKFQVCVGSPTTLRAAFMGDSGGPLLCAGVAHGIVSYGHPDAKPPAIFTRVSTYVPWINAVINTSS", "length": 247 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-133", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-133#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P04187-1", "protein_name": "Granzyme B(G,H)", "gene_name": "Gzmb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKILLLLLTLSLASRTKAGEIIGGHEVKPHSRPYMALLSIKDQQPEAICGGFLIREDFVLTAAHCEGSIINVTLGAHNIKEQEKTQQVIPMVKCIPHPDYNPKTFSNDIMLLKLKSKAKRTRAVRPLNLPRRNVNVKPGDVCYVAGWGRMAPMGKYSNTLQEVELTVQKDRECESYFKNRYNKTNQICAGDPKTKRASFRGDSGGPLVCKKVAAGIVSYGYKDGSPPRAFTKVSSFLSWIKKTMKSS", "length": 247 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-133", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-133#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P08246-1", "protein_name": "Neutrophil elastase", "gene_name": "ELANE", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTLGRRLACLFLACVLPALLLGGTALASEIVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNLSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSLCRRSNVCTLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRSEDNPCPHPRDPDPASRTH", "length": 267 }, "evidence": [ { "id": "RGD:1307968", "url": "https://alliancegenome.org/gene/RGD:1307968#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P08311-1", "protein_name": "Cathepsin G", "gene_name": "CTSG", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQPLLLLLAFLLPTGAEAGEIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSNINVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGLRPGTLCTVAGWGRVSMRRGTDTLREVQLRVQRDRQCLRIFGSYDPRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSSGVPPEVFTRVSSFLPWIRTTMRSFKLLDQMETPL", "length": 255 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-133", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-133#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P08882-1", "protein_name": "Granzyme C", "gene_name": "Gzmc", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPPVLILLTLLLPLRAGAEEIIGGNEISPHSRPYMAYYEFLKVGGKKMFCGGFLVRDKFVLTAAHCKGSSMTVTLGAHNIKAKEETQQIIPVAKAIPHPDYNPDDRSNDIMLLKLVRNAKRTRAVRPLNLPRRNAHVKPGDECYVAGWGKVTPDGEFPKTLHEVKLTVQKDQVCESQFQSSYNRANEICVGDSKIKGASFEEDSGGPLVCKRAAAGIVSYGQTDGSAPQVFTRVLSFVSWIKKTMKHS", "length": 248 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-133", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-133#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P08883-1", "protein_name": "Granzyme F", "gene_name": "Gzmf", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPPILILLTLLLPLRAGAEEIIGGHEVKPHSRPYMARVRFVKDNGKRHSCGGFLVQDYFVLTAAHCTGSSMRVILGAHNIRAKEETQQIIPVAKAIPHPAYDDKDNTSDIMLLKLESKAKRTKAVRPLKLPRPNARVKPGHVCSVAGWGRTSINATQRSSCLREAQLIIQKDKECKKYFYKYFKTMQICAGDPKKIQSTYSGDSGGPLVCNNKAYGVLTYGLNRTIGPGVFTKVVHYLPWISRNMKLL", "length": 248 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-133", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-133#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P08884-1", "protein_name": "Granzyme E", "gene_name": "Gzme", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPPVLILLTLLLPLGAGAEEIIGGHVVKPHSRPYMAFVKSVDIEGNRRYCGGFLVQDDFVLTAAHCRNRTMTVTLGAHNIKAKEETQQIIPVAKAIPHPDYNATAFFSDIMLLKLESKAKRTKAVRPLKLPRPNARVKPGDVCSVAGWGSRSINDTKASARLREAQLVIQEDEECKKRFRHYTETTEICAGDLKKIKTPFKGDSGGPLVCDNKAYGLLAYAKNRTISSGVFTKIVHFLPWISRNMKLL", "length": 248 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-133", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-133#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P10144-1", "protein_name": "Granzyme B", "gene_name": "GZMB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQPILLLLAFLLLPRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSFKGDSGGPLVCNKVAQGIVSYGRNNGMPPRACTKVSSFVHWIKKTMKRY", "length": 247 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-133", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-133#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P11033-1", "protein_name": "Granzyme D", "gene_name": "Gzmd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPPILILLTLLLPLRAGAEEIIGGHVVKPHSRPYMAFVMSVDIKGNRIYCGGFLIQDDFVLTAAHCKNSSVQSSMTVTLGAHNITAKEETQQIIPVAKDIPHPDYNATIFYSDIMLLKLESKAKRTKAVRPLKLPRSNARVKPGDVCSVAGWGSRSINDTKASARLREVQLVIQEDEECKKRFRYYTETTEICAGDLKKIKTPFKGDSGGPLVCDNQAYGLFAYAKNGTISSGIFTKVVHFLPWISWNMKLL", "length": 252 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-133", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-133#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P11034-1", "protein_name": "Mast cell protease 1", "gene_name": "Mcpt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQALLFLMALLLPSGAGAEEIIGGVEARPHSRPYMAHLKIITDRGSEDRCGGFLIAPQFVLTAAHCKGREITVTLGAHDVSKSESTQQRIKVEKQIIHKNYNVSFNLYDIMLLKLEEKAELTPTVDVIPLPGPSDFIDPGKMCWTAGWGKTGEKEPTSETLREVELRIMDKEACKMYKHYDYNFQVCVGSSTKLKTAYMGDSGGPLLCAGVAHGIVSYGDSHGKPPAVFTRISAYVPWIKTVINGK", "length": 246 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-133", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-133#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P13366-1", "protein_name": "Granzyme G", "gene_name": "Gzmg", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPPILILLTLLLPLRAGAEEIIGGHEVKPHSRPYMAFIKSVDIEGKKKYCGGFLVQDDFVLTAAHCRNRSMTVTLGAHNIKAKEETQQIIPVAKAIPHPAFNRKHGTNDIMLLKLESKAKRTKAVRPLKLPRPNARVKPGDVCSVAGWGKTSINATKASARLREAQLIIQEDEECKKLWYTYSKTTQICAGDPKKVQAPYEGESGGPLVCDNLAYGVVSYGINRTITPGVFTKVVHFLPWISTNMKLL", "length": 248 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-133", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-133#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P15119-1", "protein_name": "Mast cell protease 2", "gene_name": "Mcpt2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQALLFLMALLLPSGAGAEEIIGGVEAKPHSRPYMAYLKFTTKNGSKERCGGFLIAPQFVMTAAHCNGSEISVILGAHNINKNEPTQQIIKTEKTFVHPKFQYLSGFYDIMLLKLQKKAELNSDVDVISLPSSSDFIKPGKMCWTAGWGKTGKNNPLSVTLREVELRIMDQEACKDHSDYDYQLQVCAGSPTTSKSIGQGDSGGPLVCDSVAHGIASSYEAKAPAVFTRISYYLPWIYKVLKSK", "length": 244 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-133", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-133#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P17977-1", "protein_name": "Cathepsin G", "gene_name": "Ctsg", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQPLLFLLIFVLFQEDEAGKIIGGREARPNSHPYMAFLLIQSPEGLSACGGFLVREDFVLTAGHCFGSSINVTLGAHNIRRQEGTQQHITVLRAIRHPDYNPPPVIQNDIMLLQLRSRARRSRAVKPVALPQATKRVQPGALCTVAGWGLVSQRRGTNVLQEVKLRVQTDQTCANRFQFYNSQTQICVGNPRERKSAFKGDSGGPLVCNNVAQGIVSYGSSSGNPPAVFTRIQSFMPWIKRTMRRLSSRY", "length": 250 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-133", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-133#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P18291-1", "protein_name": "Granzyme B", "gene_name": "Gzmb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKLLLLLLSFSLAPKTEAGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRASFRGDSGGPLVCKKVAAGIVSYGQNDGSTPRAFTKVSTFLSWIKKTMKKS", "length": 248 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-133", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-133#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P20718-1", "protein_name": "Granzyme H", "gene_name": "GZMH", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQPFLLLLAFLLTPGAGTEEIIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTAAHCQGSSINVTLGAHNIKEQERTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKWTTAVRPLRLPSSKAQVKPGQLCSVAGWGYVSMSTLATTLQEVLLTVQKDCQCERLFHGNYSRATEICVGDPKKTQTGFKGDSGGPLVCKDVAQGILSYGNKKGTPPGVYIKVSHFLPWIKRTMKRL", "length": 246 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-133", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-133#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P21812-1", "protein_name": "Mast cell protease 4", "gene_name": "Mcpt4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQALLFLMALLLPSGAGAEEIIGGVESRPHSRPYMAHLEITTERGFTATCGGFLITRQFVMTAAHCSGREITVTLGAHDVSKTESTQQKIKVEKQIVHPKYNFYSNLHDIMLLKLQKKAKETPSVNVIPLPRPSDFIKPGKMCRAAGWGRTGVTEPTSDTLREVKLRIMDKEACKNYWHYDYNLQVCVGSPRKKRSAYKGDSGGPLLCAGVAHGIVSYGRGDAKPPAVFTRISSYVPWINRVIKGE", "length": 246 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-133", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-133#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P21844-1", "protein_name": "Chymase", "gene_name": "Cma1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHLLTLHLLLLLLGSSTKAGEIIGGTECIPHSRPYMAYLEIVTSENYLSACSGFLIRRNFVLTAAHCAGRSITVLLGAHNKTSKEDTWQKLEVEKQFLHPKYDENLVVHDIMLLKLKEKAKLTLGVGTLPLSANFNFIPPGRMCRAVGWGRTNVNEPASDTLQEVKMRLQEPQACKHFTSFRHNSQLCVGNPKKMQNVYKGDSGGPLLCAGIAQGIASYVHRNAKPPAVFTRISHYRPWINKILREN", "length": 247 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-133", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-133#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P23946-1", "protein_name": "Chymase", "gene_name": "CMA1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLLLPLPLLLFLLCSRAEAGEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQLCVGNPRKTKSAFKGDSGGPLLCAGVAQGIVSYGRSDAKPPAVFTRISHYRPWINQILQAN", "length": 247 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-133", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-133#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P28293-1", "protein_name": "Cathepsin G", "gene_name": "Ctsg", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQPLLLLLTFILLQGDEAGKIIGGREARPHSYPYMAFLLIQSPEGLSACGGFLVREDFVLTAAHCLGSSINVTLGAHNIQMRERTQQLITVLRAIRHPDYNPQNIRNDIMLLQLRRRARRSGSVKPVALPQASKKLQPGDLCTVAGWGRVSQSRGTNVLQEVQLRVQMDQMCANRFQFYNSQTQICVGNPRERKSAFRGDSGGPLVCSNVAQGIVSYGSNNGNPPAVFTKIQSFMPWIKRTMRRFAPRYQRPANSLSQAQT", "length": 261 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-133", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-133#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P43430-1", "protein_name": "Mast cell protease 8", "gene_name": "Mcpt8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFLLLVLLVAALPVNAEGGEIIWGTESKPHSRPYMAYIRFNDSKSVYRCGGFLVARDIVMTAAHCNGKVINVTLGIHNLKKKKNTQLIPVSEAIPHESFDNETLVNDIMLLKLERKAQLNSAVDTIALPKSKDWVKPGQVCTVAGWGKLANCTLSDTLQEVNLEVQKGQKCRSMSQTYNDSIQLCVGNPSENKATGKGDSGGPFVCNGVVQGIVSCRLCTGTLPRVFTRISSFMPWIRKTMKLLQQP", "length": 247 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-133", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-133#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P50339-1", "protein_name": "Chymase", "gene_name": "Cma1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNLHALCLLLLLLGSSTKAGEIIGGTECIPHSRPYMAYLEIVTSDNYLSACSGFLIRRNFVLTAAHCAGRSITVLLGAHNKTYKEDTWQKLEVEKQFIHPNYDKRLVLHDIMLLKLKEKAKLTLGVGTLPLSANFNFIPPGRMCRAVGWGRTNVNEPASDTLQEVKMRLQEPQSCKHFTSFQHKSQLCVGNPKKMQNVYKGDSGGPLLCAGIAQGIASYVHPNAKPPAVFTRISHYRPWINKILREN", "length": 247 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-133", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-133#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P51124-1", "protein_name": "Granzyme M", "gene_name": "GZMM", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEACVSSLLVLALGALSVGSSFGTQIIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVLTAAHCLAQRMAQLRLVLGLHTLDSPGLTFHIKAAIQHPRYKPVPALENDLALLQLDGKVKPSRTIRPLALPSKRQVVAAGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNSRFWNGSLSPSMVCLAADSKDQAPCKGDSGGPLVCGKGRVLARVLSFSSRVCTDIFKPPVATAVAPYVSWIRKVTGRSA", "length": 257 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-133", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-133#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P97592-1", "protein_name": "Mast cell protease 4", "gene_name": "Mcpt4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKALLFLMALLLPSGAGAEEIIGGVESIPHSRPYMALLKIVTEEGHVTFCGGFLISLQFVLTAAHCHGREITVTLGAHDMSKRESTQQKIKVVKQIFPLKYNLFSNFRDIMLLKLEQKAVLTPSVNVIPLPQSSDIIKPGTMCLAAGWGQTGVKEPNSNTLREVMLRIMEMKACKDYRHYDNRFQICVGIPQMLKLAYKGDSGGPLVCAGVAHGIVSHGPGRGIPPIIFTRISSYVSWINRVIRGN", "length": 246 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-133", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-133#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P97594-1", "protein_name": "Mast cell protease 8", "gene_name": "Mcpt8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFLFLFFLVAILPVNTEGGEIIWGTESKPHSRPYMAFIKFYDSNSEPHHCGGFLVAKDIVMTAAHCNGRNIKVTLGAHNIKKQENTQVISVVKAKPHENYDRDSHFNDIMLLKLERKAQLNGVVKTIALPRSQDWVKPGQVCTVAGWGRLANCTSSNTLQEVNLEVQKGQKCQDMSEDYNDSIQLCVGNPSEGKATGKGDSGGPFVCDGVAQGIVSYRLCTGTLPRVFTRISSFIPWIQKTMKVLQQS", "length": 248 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-133", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-133#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q00356-1", "protein_name": "Mast cell protease-like protein", "gene_name": "Mcptl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQALLFLMALLLPSGAGAEEIIGGVESEPHSRPYMAYVNTFRRKGYVAICGGFLITPQFVMTAAHCRGRRMTVTLGAHNVRKRECTQQKIKVEKYILPPNYNVSSKFNDIVLLKLKKQANLTSAVDVVPLPGPSDFAKPGTMCWAAGWGRTGVKKIISHTLREVELKIVGEKACKIFRHYKDSLQICVGSSTKVASVYMGDSGGPLLCAGVAHGIVSSGRGNAKPPAIFTRISPHVPWINRVIKGK", "length": 246 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-133", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-133#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q06606-1", "protein_name": "Granzyme-like protein 2", "gene_name": "Mcpt10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFLFLIFLVAVLPVNTEGGEIVWGTESKPHSRPYMASLMFYYGNSYRHYCGGFLVAKDIVMTAAHCNESNIKVILGAHNIKKRENTQVFSVVKAKPHENYDSHSLFNDIMLLKLERKAQLNGVVKTIALPRSQDWVKPGQVCTVAGWGRLANCTLSNTLQEVNLEVQKGQKCQGMSEDYNDSIQLCVGNPSEGKATGKGDSGGPFVCDGVAQGIVSRRLCTGTLPRVFTRISTFIPWIQKTMKLLQQP", "length": 248 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-133", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-133#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3UP87-1", "protein_name": "Neutrophil elastase", "gene_name": "Elane", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGRLSSRTLAAMLLALFLGGPALASEIVGGRPARPHAWPFMASLQRRGGHFCGATLIARNFVMSAAHCVNGLNFRSVQVVLGAHDLRRQERTRQTFSVQRIFENGFDPSQLLNDIVIIQLNGSATINANVQVAQLPAQGQGVGDRTPCLAMGWGRLGTNRPSPSVLQELNVTVVTNMCRRRVNVCTLVPRRQAGICFGDSGGPLVCNNLVQGIDSFIRGGCGSGLYPDAFAPVAEFADWINSIIRSHNDHLLTHPKDREGRTN", "length": 265 }, "evidence": [ { "id": "RGD:1307968", "url": "https://alliancegenome.org/gene/RGD:1307968#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IRE2-1", "protein_name": "trypsin", "gene_name": "Dmel\\CG32271", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MATLWLVLHLIPLCWAASNEANSRIVGGVPVDIASVPYLVNLRIGGNFMCGGSLVTPQHVVTAAHCVKGIGASRILVVAGVTRLTETGVRSGVDKVYTPKAYNTRTLTSDVAVLKLKAPISGPKVSTIELCNTSFKAGDLIKVSGWGQITERNKAVSMQVRSVDVALIPRKACMSQYKLRGTITNTMFCASVPGVKDACEGDSGGPAVYQGQLCGIVSWGVGCARKSSPGVYTNVKTVRSFIDKALGM", "length": 248 }, "evidence": [ { "id": "RGD:1307968", "url": "https://alliancegenome.org/gene/RGD:1307968#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q91VB1-1", "protein_name": "Chymase 2, mast cell", "gene_name": "Cma2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQALLFLMALLLPSRAGAEEIIGGVESEPHSRPYMAYVNTFRRKGYVAICGGFLITPQFVMTAAHCSGRRMTVTLGAHNVRKRECTQQKIKVEKYILPPNYNVSSKFNDIVLLKLKKQANLTSAVDVVPLPAPSDFAKPGTMCWAAGWGRTGLKKSISRTLREVELRIMGKKACKIFKHYKDSLQICVGSSTKVASVYMGDSGGPLLCAGVAHGIVSSGRGNAKPPAIFTRISPHVPWINRVIEGK", "length": 246 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-133", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-133#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VZT0-1", "protein_name": "trypsin", "gene_name": "CG11532", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVGLRLLWWLCHLALVLPSSSSKTRIVGGKETTISEVPYLVYLRQNGYFICGGSLISSRAVLSAAHCVYGSQPEGFTVHAGASRLDQEAPVVRNVVMFHTSPSYSATNFDMDVALLQLQEVVVLTPGKVATISPCRNPPEGNAYARISGWGVTRENNREPAEQVRTTMVRVLPGAECKISYSGYGQLSDSMLCAAVRGLRDSCSGDSGGPLVYRGQVCGIVSWGFGCARPSFPGVYTNVASERVHEFIEQTLRRIGS", "length": 257 }, "evidence": [ { "id": "RGD:1307968", "url": "https://alliancegenome.org/gene/RGD:1307968#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q9VXC8", "url": "https://www.uniprot.org/uniprotkb/Q9VXC8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9VXC8", "url": "https://www.uniprot.org/uniprotkb/Q9VXC8" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "Q9VXC8", "url": "https://www.uniprot.org/uniprotkb/Q9VXC8" } ], "pmid": "" }, { "name": "defense response to Gram-positive bacterium", "id": "GO:0050830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050830", "evidence": [ { "database": "UniProtKB", "id": "Q9VXC8", "url": "https://www.uniprot.org/uniprotkb/Q9VXC8" } ], "pmid": "" }, { "name": "defense response to fungus", "id": "GO:0050832", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050832", "evidence": [ { "database": "UniProtKB", "id": "Q9VXC8", "url": "https://www.uniprot.org/uniprotkb/Q9VXC8" } ], "pmid": "" }, { "name": "positive regulation of antibacterial peptide biosynthetic process", "id": "GO:0006963", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006963", "evidence": [ { "database": "UniProtKB", "id": "Q9VXC8", "url": "https://www.uniprot.org/uniprotkb/Q9VXC8" } ], "pmid": "" }, { "name": "Toll receptor ligand protein activation cascade", "id": "GO:0160032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160032", "evidence": [ { "database": "UniProtKB", "id": "Q9VXC8", "url": "https://www.uniprot.org/uniprotkb/Q9VXC8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "Q9VXC8", "url": "https://www.uniprot.org/uniprotkb/Q9VXC8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VXC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXC8" }, { "id": "PS50240", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50240" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase S1", "eco_id": "ECO_0000259", "start_pos": 26, "end_pos": 249, "start_aa": "Ile", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.21.4", "ec_name": "Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.", "evidence": [ { "id": "3.4.21.4", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.21.4" } ] } ], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VXE2-1", "uniprot_ac": "Q9VXE2", "uniprot_id": "Q9VXE2_DROME", "mass": { "chemical_mass": 46837.0, "monoisotopic_mass": 46837.0 }, "refseq": { "ac": "NP_573138", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573138" }, "gene_names": [ { "name": "Dmel\\CG9777", "type": "recommended", "evidence": [ { "id": "Q9VXE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXE2" } ] }, { "name": "CG9777", "type": "synonym", "evidence": [ { "id": "NP_573138", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573138" }, { "id": "Q9VXE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXE2" } ] }, { "name": "Dmel\\CG9777", "type": "synonym", "evidence": [ { "id": "NP_573138", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573138" } ] }, { "name": "Dmel_CG9777", "type": "synonym", "evidence": [ { "id": "Q9VXE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXE2" } ] } ], "protein_names": [ { "name": "CG9777-PA", "type": "synonym", "evidence": [ { "id": "NP_573138", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573138" } ] }, { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "Q9VXE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXE2/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_573138", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573138" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VXE2", "url": "https://www.uniprot.org/uniprotkb/Q9VXE2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG9777", "url": "https://www.uniprot.org/uniprotkb/Q9VXE2", "locus": { "chromosome": "X", "start_pos": 16630673, "end_pos": 16632235, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0030764", "url": "https://www.ensemblgenomes.org/id/FBgn0030764" } ] } } ], "crossref": [ { "id": "FB:FBgn0030764", "url": "https://alliancegenome.org/gene/FB:FBgn0030764", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0030764", "url": "https://bgee.org/?page=gene&gene_id=FBgn0030764", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0030764", "url": "https://flybase.org/reports/FBgn0030764", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "32633", "url": "https://www.ncbi.nlm.nih.gov/gene/32633", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dme:Dmel_CG9777", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG9777", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q9VXE2", "url": "https://www.orthodb.org/?gene=Q9VXE2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "NP_573138", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573138", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VXE2", "url": "https://www.uniprot.org/uniprotkb/Q9VXE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VXE2-1", "url": "https://www.uniprot.org/uniprotkb/Q9VXE2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYNLIKSRTLSDYLKKPMPPNSLNNGGKTNNSVGNTNNPAGNLSPVAEECVPHPKNKERTLVEDLAKINKLFEYLEASATDDMDLDNSTVEDVGKESLSNTVQAWKEVPNIKNKYFIGEQVPVMDTSDFMLISRNKAKKTLRARQMRLEQERKVALEAAKLTEQKGMGDPSSVPGNDSNDNEAQPVVHLSRSPIKYSMDERTGVNRMRATKKKQIERALFSENSMQLDQEQMQLAVEEDENQKADGPVAALTHKRYIPTHKEWEEQRRLKAENSQTTVDQMTPATTMTAKRYIPTTKEWDEQRRFKLKAKMETKKNATSANSTNELGAEKRKGNSTHYGANIDWTNLTRTNNNFQKMASQPMPIEGEQKDRQVKKGNVIRYTIDELLKLEPQPDDLDVPAEVALIDKKLLKGN", "length": 413, "header": "tr|Q9VXE2-1|Q9VXE2_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG9777 PE=4 SV=1 CANONICAL=Q9VXE2-1" }, "isoforms": [ { "isoform_ac": "Q9VXE2-1", "url": "https://www.uniprot.org/uniprotkb/Q9VXE2/entry#Q9VXE2-1", "sequence": { "sequence": "MYNLIKSRTLSDYLKKPMPPNSLNNGGKTNNSVGNTNNPAGNLSPVAEECVPHPKNKERTLVEDLAKINKLFEYLEASATDDMDLDNSTVEDVGKESLSNTVQAWKEVPNIKNKYFIGEQVPVMDTSDFMLISRNKAKKTLRARQMRLEQERKVALEAAKLTEQKGMGDPSSVPGNDSNDNEAQPVVHLSRSPIKYSMDERTGVNRMRATKKKQIERALFSENSMQLDQEQMQLAVEEDENQKADGPVAALTHKRYIPTHKEWEEQRRLKAENSQTTVDQMTPATTMTAKRYIPTTKEWDEQRRFKLKAKMETKKNATSANSTNELGAEKRKGNSTHYGANIDWTNLTRTNNNFQKMASQPMPIEGEQKDRQVKKGNVIRYTIDELLKLEPQPDDLDVPAEVALIDKKLLKGN", "length": 413, "header": "tr|Q9VXE2-1|Q9VXE2_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG9777 PE=4 SV=1 CANONICAL=Q9VXE2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VXE2", "url": "https://www.uniprot.org/uniprotkb/Q9VXE2" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VXE2", "url": "https://www.uniprot.org/uniprotkb/Q9VXE2" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXE2", "url": "https://www.uniprot.org/uniprotkb/Q9VXE2" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker 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Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VXF0", "url": "https://www.uniprot.org/uniprotkb/Q9VXF0" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VXF0", "url": "https://www.uniprot.org/uniprotkb/Q9VXF0" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXF0", "url": "https://www.uniprot.org/uniprotkb/Q9VXF0" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXF0", "url": "https://www.uniprot.org/uniprotkb/Q9VXF0" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"MDIIFSQDVHDEQKFLDCARKLEYDEFSAKMFVFCNKHSALDVFELMGDDRLSQLLYGWEVCHLPTRDSESLKDPALRHMVRVLVYHSLLMWFSQEWKTCSEGLKQLLLYTLTKAMPAFHQIGELANINWSYVLQFQTKPWSLPYLHQLFLNLELNKQHGIEHKVQAASGEDVAFLMQEGVSLALLRLIQLFNAGNFEAVKQLALRMLAAWLKIHENAPFVSFKGDENTITLIGHVCLLAAFVRDDNQGFVIDNLMYNIGFYVQIMEEFSSSHDINFTPARLIARVCVRLRLGKNAFFEKIAFRKFNLCMVTSFAVILDAYSSYVLGNLLMDLQSLNEHDFLEHLPQFKKLMDRYVEERESSERFLLNELKKMEQQRNSCIEPHLVNLILNYKQQICKGNRASNISNYKNSDDDEKIQPEVGEEQDRQVDPVFQNVPNNEEVLSFVYKLLAERNFSGWRFAKIALLLKIIGQQINALEMWRYHPGLTVDFMLDLEQKMSANYADLAKLFSDHGFMEAEFWLTAFYLHPTSSNYNEVKRCSWIMKNRQEEGGLPAPAIGNVKYELLSSTIDVHQIMTITNHEDPVSDYDPINESLKALRLPSNMTKDLLTVVFQPRHKQYSWALDWQTLDERCSALLKSQDLKRKFVSLNMAESCDDLKYLQIDYAKYRDRPQLDYGTIEEGYENETNLSNAAGKAESTPAVHDKAEKAKELKMRRHAKRKCWYEVSEDEEEAASSDSEPSYTGNGRRTQIRAAAIASKANGRRTGIRAAAIAANIKLSEMSFPETSNRRFSTQPVVKEQPKIAVQPKKQKTVLFSKEEDEVSSSDSEPCYTGNGRRTQMRAAAIAAKAKLSEISSPETSNKHFSTRSIVNEQPRIAVQSRKQKAVMFSKDGDETSSSDSEHCYTRNGHLNRIRAAAIAAKANLPELDRKVSGGRRSIFPEASGNHFVTQPVVAEQPKIAVQPQNQQKRTIAELMKSRPMFTNETKGFKPIADIWSFSKEELENVVSGPNDMIECSSIIAKMKLLKDLKMAKSAKAAGQPCSQLVRTGSETESVNSETSTMATHEFNEKGTTVGSPGEGKEQKTPSPTANSELSTETEVLKPTDETEAHMIHDALKTTNVPQKTLDLQFLSKKHIRTG", "length": 1137, "header": "tr|Q9VXF4-1|Q9VXF4_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG9902 PE=4 SV=1 CANONICAL=Q9VXF4-1" }, "isoforms": [ { "isoform_ac": "Q9VXF4-1", "url": "https://www.uniprot.org/uniprotkb/Q9VXF4/entry#Q9VXF4-1", "sequence": { "sequence": 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"length": 1137, "header": "tr|Q9VXF4-1|Q9VXF4_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG9902 PE=4 SV=1 CANONICAL=Q9VXF4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 837, "start_aa": "Thr", "end_pos": 837, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr837", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "Q9VXF4", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9VXF4" } ], "filter_code": "00000000000000001000.0000000.00000001000000.1000000.0100000000.110100100001111011.10000.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_reported_with_glycan" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VXF4", "url": "https://www.uniprot.org/uniprotkb/Q9VXF4" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, 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"MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021056", "name": "familial adenomatous polyposis 1", "description": "" }, { "id": "MIM:175100", "resource": "MIM", "url": "https://www.omim.org/entry/175100", "name": "Familial adenomatous polyposis 1", "description": "Familial adenomatous polyposis 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "0050424", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050424" } ] }, { "disease_id": "DOID:0050866", "recommended_name": { "id": "DOID:0050866", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050866", "name": "oral squamous cell carcinoma", "description": "An oral cavity cancer that has_material_basis_in squamous cells." }, "synonyms": [ { "id": "DOID:0050866", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050866", "name": "mouth squamous cell carcinoma", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "0050866", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050866" } ] }, { "disease_id": "DOID:0070615", "recommended_name": { "id": "DOID:0070615", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070615", "name": "autoinflammation, antibody deficiency, and immune dysregulation syndrome", "description": "An autoimmune disease characterized by recurrent blistering skin lesions with a dense inflammatory infiltrate and variable involvement of other tissues, including joints, the eye, and the gastrointestinal tract that has_material_basis in heterozygous mutation in the PLCG2 gene on chromosome 16q23." }, "synonyms": [ { "id": "DOID:0070615", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070615", "name": "APLAID", "description": "" }, { "id": "DOID:0070615", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070615", "name": "autoinflammation and PLCG2-associated antibody deficiency and immune dysregulation", "description": "" }, { "id": "MONDO:0013944", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013944", "name": "autoinflammation-PLCG2-associated antibody deficiency-immune dysregulation", "description": "" }, { "id": "MONDO:0013944", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013944", "name": "APLAID", "description": "" }, { "id": "MONDO:0013944", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013944", "name": "AUTOINFLAMMATION, antibody deficiency, and immune dysregulation, PLCG2-associated", "description": "" }, { "id": "MIM:614878", "resource": "MIM", "url": "https://www.omim.org/entry/614878", "name": "Autoinflammation, antibody deficiency, and immune dysregulation", "description": "Autoinflammation, antibody deficiency, and immune dysregulation" } ], "unlinked_id_list": [], "evidence": [ { "id": "0070615", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070615" } ] }, { "disease_id": "DOID:0090064", "recommended_name": { "id": "DOID:0090064", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090064", "name": "familial cold autoinflammatory syndrome 3", "description": "A familial cold autoinflammatory syndrome characterized by autosomal dominant inheritance of development of cutaneous urticaria, erythema and pruritus in response to cold exposure with. FCAS3 has_material_basis_in heterozygous deletion within the PLCG2 gene on chromosome 16q." }, "synonyms": [ { "id": "DOID:0090064", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090064", "name": "phospholipase C gamma 2-associated antibody deficiency and immune dysregulation", "description": "" }, { "id": "DOID:0090064", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090064", "name": "FACU", "description": "" }, { "id": "DOID:0090064", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090064", "name": "FCAS3", "description": "" }, { "id": "DOID:0090064", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090064", "name": "PLAID", "description": "" }, { "id": "DOID:0090064", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090064", "name": "familial atypical cold urticaria", "description": "" }, { "id": "DOID:0090064", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090064", "name": "PLCG2-associated antibody deficiency and immune dysregulation", "description": "" }, { "id": "MONDO:0013766", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013766", "name": "familial cold autoinflammatory syndrome 3", "description": "A rare, hereditary, immune deficiency with skin involvement characterized by early-onset cold urticaria after generalized exposure to cold air or evaporative cooling and not after contact with cold objects. Additional immunologic abnormalities are often present - antibody deficiency, recurrent infections, autoimmune disease and symptomatic allergic disease." }, { "id": "MONDO:0013766", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013766", "name": "FACU", "description": "" }, { "id": "MONDO:0013766", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013766", "name": "PLAID", "description": "" }, { "id": "MONDO:0013766", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013766", "name": "PLCG2 familial cold autoinflammatory syndrome", "description": "" }, { "id": "MONDO:0013766", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013766", "name": "familial atypical cold urticaria", "description": "" }, { "id": "MONDO:0013766", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013766", "name": "familial cold autoinflammatory syndrome 3", "description": "" }, { "id": "MONDO:0013766", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013766", "name": "familial cold autoinflammatory syndrome caused by mutation in PLCG2", "description": "" }, { "id": "MONDO:0013766", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013766", "name": "familial cold autoinflammatory syndrome type 3", "description": "" }, { "id": "MONDO:0013766", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013766", "name": "familial cold urticaria with common variable immunodeficiency", "description": "" }, { "id": "MONDO:0013766", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013766", "name": "plaid", "description": "" }, { "id": "MONDO:0013766", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013766", "name": "FCAS3", "description": "" }, { "id": "MIM:614468", "resource": "MIM", "url": "https://www.omim.org/entry/614468", "name": "Familial cold autoinflammatory syndrome 3", "description": "Familial cold autoinflammatory syndrome 3" } ], "unlinked_id_list": [], "evidence": [ { "id": "0090064", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090064" } ] }, { "disease_id": "DOID:10652", "recommended_name": { "id": "DOID:10652", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid." }, "synonyms": [ { "id": "DOID:10652", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10652", "name": "Alzheimer disease", "description": "" }, { "id": "DOID:10652", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10652", "name": "Alzheimers dementia", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ] }, { "disease_id": "DOID:1612", "recommended_name": { "id": "DOID:1612", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland." }, "synonyms": [ { "id": "DOID:1612", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1612", "name": "breast tumor", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1612", "name": "malignant neoplasm of breast", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1612", "name": "malignant tumor of the breast", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1612", "name": "mammary cancer", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1612", "name": "mammary tumor", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1612", "name": "primary breast cancer", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "hereditary breast carcinoma", "description": "Breast carcinoma that has developed in relatives of patients with history of breast carcinoma." }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer susceptibility, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, early-onset, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, invasive ductal, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, lobular, somatic", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, male, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, protection against, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, somatic", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial breast cancer", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial breast carcinoma", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial cancer of breast", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial cancer of the breast", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "hereditary breast cancer", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "hereditary breast carcinoma", "description": "" }, { "id": "MIM:114480", "resource": "MIM", "url": "https://www.omim.org/entry/114480", "name": "Breast cancer", "description": "Breast cancer" } ], "unlinked_id_list": [ "DOID:3017", "DOID:0050938" ], "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ] }, { "disease_id": "DOID:219", "recommended_name": { "id": "DOID:219", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:219", "name": "colon cancer", "description": "A colorectal cancer that is located_in the colon." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:219" } ] }, { "disease_id": "DOID:2876", "recommended_name": { "id": "DOID:2876", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2876", "name": "laryngeal squamous cell carcinoma", "description": "A laryngeal carcinoma that has_material_basis_in squamous cells." }, "synonyms": [ { "id": "DOID:2876", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2876", "name": "Epidermoid carcinoma of the Larynx", "description": "" }, { "id": "DOID:2876", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2876", "name": "squamous cell carcinoma of larynx", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "2876", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2876" } ] }, { "disease_id": "DOID:3459", "recommended_name": { "id": "DOID:3459", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3459", "name": "breast carcinoma", "description": "A breast cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells." }, "synonyms": [ { "id": "DOID:3459", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3459", "name": "Mammary carcinoma", "description": "" }, { "id": "DOID:3459", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3459", "name": "carcinoma of breast", "description": "" } ], "unlinked_id_list": [ "DOID:0050938" ], "evidence": [ { "id": "3459", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3459" } ] }, { "disease_id": "DOID:3908", "recommended_name": { "id": "DOID:3908", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma." }, "synonyms": [ { "id": "DOID:3908", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3908", "name": "NSCLC", "description": "" }, { "id": "DOID:3908", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3908", "name": "Non-small cell lung cancer", "description": "" }, { "id": "DOID:3908", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3908", "name": "non-small cell lung carcinoma", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ] }, { "disease_id": "DOID:3910", "recommended_name": { "id": "DOID:3910", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3910", "name": "lung adenocarcinoma", "description": "A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin." }, "synonyms": [ { "id": "DOID:3910", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3910", "name": "bronchogenic lung adenocarcinoma", "description": "" }, { "id": "DOID:3910", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3910", "name": "nonsmall cell adenocarcinoma", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "3910", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3910" } ] }, { "disease_id": "DOID:684", "recommended_name": { "id": "DOID:684", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver." }, "synonyms": [ { "id": "DOID:684", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:684", "name": "Hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma", "description": "A malignant tumor that arises from hepatocytes. Hepatocellular carcinoma is relatively rare in the United States but very common in all African countries south of the Sahara and in Southeast Asia. Most cases are seen in patients over the age of 50 years, but this tumor can also occur in younger individuals and even in children. Hepatocellular carcinoma is more common in males than females and is associated with hepatitis B, hepatitis C, chronic alcohol abuse and cirrhosis. Serum elevation of alpha-fetoprotein occurs in a large percentage of patients with hepatocellular carcinoma. Grossly, hepatocellular carcinoma may present as a single mass, as multiple nodules, or as diffuse liver involvement. Microscopically, there is a wide range of differentiation from tumor to tumor (well differentiated to poorly differentiated tumors). Hepatocellular carcinomas quickly metastasize to regional lymph nodes and lung. The overall median survival of untreated liver cell carcinoma is about 4 months. The most effective treatment of hepatocellular carcinoma is complete resection of the tumor. Lately, an increasing number of tumors have been treated with liver transplantation." }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "HCC", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "cancer, hepatocellular", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of liver", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of the liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma, hepatocellular, malignant", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatoblastoma, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular adenocarcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular cancer", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular cancer, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma, childhood type, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver cell cancer (hepatocellular carcinoma)", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver cell carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "primary carcinoma of liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "primary carcinoma of the liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "adult hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "adult primary hepatocellular carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma", "description": "A malignant tumor that arises from hepatocytes. Hepatocellular carcinoma is relatively rare in the United States but very common in all African countries south of the Sahara and in Southeast Asia. Most cases are seen in patients over the age of 50 years, but this tumor can also occur in younger individuals and even in children. Hepatocellular carcinoma is more common in males than females and is associated with hepatitis B, hepatitis C, chronic alcohol abuse and cirrhosis. Serum elevation of alpha-fetoprotein occurs in a large percentage of patients with hepatocellular carcinoma. Grossly, hepatocellular carcinoma may present as a single mass, as multiple nodules, or as diffuse liver involvement. Microscopically, there is a wide range of differentiation from tumor to tumor (well differentiated to poorly differentiated tumors). Hepatocellular carcinomas quickly metastasize to regional lymph nodes and lung. The overall median survival of untreated liver cell carcinoma is about 4 months. The most effective treatment of hepatocellular carcinoma is complete resection of the tumor. Lately, an increasing number of tumors have been treated with liver transplantation." }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "HCC", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "cancer, hepatocellular", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of liver", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of the liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma, hepatocellular, malignant", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatoblastoma, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular adenocarcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular cancer", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular cancer, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma, childhood type, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver cell cancer (hepatocellular carcinoma)", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver cell carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "primary carcinoma of liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "primary carcinoma of the liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "adult hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "adult primary hepatocellular carcinoma", "description": "" }, { "id": "MIM:114550", "resource": "MIM", "url": "https://www.omim.org/entry/114550", "name": "Hepatocellular carcinoma", "description": "Hepatocellular carcinoma" } ], "unlinked_id_list": [], "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ] }, { "disease_id": "DOID:9256", "recommended_name": { "id": "DOID:9256", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum." }, "synonyms": [ { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer", "description": "A primary or metastatic malignant neoplasm that affects the colon or rectum. 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"length": 1236, "header": "tr|Q9VXH3-1|Q9VXH3_DROME Isoform 1 of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma OS=Drosophila melanogaster OX=7227 GN=sl PE=1 SV=3 CANONICAL=Q9VXH3-1" }, "isoforms": [ { "isoform_ac": "Q9VXH3-1", "url": "https://www.uniprot.org/uniprotkb/Q9VXH3/entry#Q9VXH3-1", "sequence": { "sequence": "MSCFSAMSAPLLGEMEQTIGMLERGTIVTKLYGKQRRPDRRHLMLIRETRQLLWATVATQTPRTDYEGAIQLREIREIRVGKHSKEFRLFADDCQRFESSKCFVILHGNHFKLKSFSVVALSEIEADNWVRGLRYMVKDTLGAPYPLQIDRWLRREYYQIENVNTHSAKATEQSPAQVTIKDFKLFLAGVSCKMTTGKFMEHFTEDVRRKHDLKFDDFSRLYQKLLLPNGFASVLSGSGVANFPYSEDQQVVRPAELKQFLETEQRDVSASEISSAAIASFIRDFVQDVERDVQEPYLTFPEFVDFLFSKQNDLWNSKYDQVFMDMNLPLSSYWIASSHNTYLTGDQFSSESSCEAYARALRMGCRCIELDCWNGPDNLPYIFHGHTITSKIKFMDVIKTIKDHAFTSSEYPVILSIEQNCSLEQQRNMAQALIEVFGDMLLTQPCDRNEQHLPSPYQLRRKIILKHKKLPQFDDIANGISSTGSLGHRSSLGGAGGGAHGENDGENVRKVFKEGLLYFKDPVDKSWNLYQFVLTHQELIYSSEINESRNGNSEDDDFGLSSSCSLNSNMQQKQKDTSANDELHFGENWFHGKLEGGRKEADDLLKKYKHFGDGTFLVRESATFVGDYSLSFWRRNRPNHCRIKLKHENGSIKYYLVENFVFDSLYSLIVYYRKNMLRSSEFSIILKEPVPQPKKHEDQEWFHPNTTKEQAEQGLYRLEIGSFLVRPSVQSINAFVISFTINRKIKHCRIMQEGRLYGIDTMNFESLVSLINYYTRNPLYRNVKLSHPVSQELLRQALAEAAQGDHSGGHDDNGASNYMGSNLEENVTCKALYSYKANKPDELSFPKHAIITNVQRDNSMWWIGDYGGMIKKHLPANYVKVIDSTTEDYNSLNEEGTDGRTDSIEIFGAVASLFESNDPGIIFKLQIQTPTMQNPFVIGFDNQETAYEWIKAIQEAALIASQLASERRKKERTARVAKEMSDLIIYFRSVPFREHSWIFQEMSSFPETKAEKQFFQQNTQLFLSYHRNQISRVYPKGQRLDSSNFNPMPFWNVGSQMIALNYQTGDKAMQLNQAKFRNNGQCGYILKPSFMKSDSFNPNNPLCDGLSEVKVSIRLIAARHLFRGGKSNNPQIVVELIGASFDTGVKYRTKVNENGFNPVWNESCEFNVRNPQFAILRFEVQDEDMFAETHFIAQACYPLTCIRQGYRSVILRNKFSEELELSSLLINIKIANVTAP", "length": 1236, "header": "tr|Q9VXH3-1|Q9VXH3_DROME Isoform 1 of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma OS=Drosophila melanogaster OX=7227 GN=sl PE=1 SV=3 CANONICAL=Q9VXH3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VXH3", "url": "https://www.uniprot.org/uniprotkb/Q9VXH3" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VXH3", "url": "https://www.uniprot.org/uniprotkb/Q9VXH3" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXH3", "url": "https://www.uniprot.org/uniprotkb/Q9VXH3" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXH3", "url": "https://www.uniprot.org/uniprotkb/Q9VXH3" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VXH3", "url": "https://www.uniprot.org/uniprotkb/Q9VXH3" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VXH3", "url": "https://www.uniprot.org/uniprotkb/Q9VXH3" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VXH3", "url": "https://www.uniprot.org/uniprotkb/Q9VXH3" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXH3", "url": "https://www.uniprot.org/uniprotkb/Q9VXH3" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXH3", "url": "https://www.uniprot.org/uniprotkb/Q9VXH3" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VXH3", "url": "https://www.uniprot.org/uniprotkb/Q9VXH3" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VXH3", "url": "https://www.uniprot.org/uniprotkb/Q9VXH3" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], 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"MADLEVYKNLSPEKVERCMSVMQSGTQMIKLKRGTKGLVRLFYLDEHRTRLRWRPSRKSEKAKILIDSIYKVTEGRQSEIFHRQAEGNFDPSCCFTIYHGNHMESLDLITSNPEEARTWITGLKYLMAGISDEDSLAKRQRTHDQWVKQTFEEADKNGDGLLNIEEIHQLMHKLNVNLPRRKVRQMFQEADTDENQGTLTFEEFCVFYKMMSLRRDLYLLLLSYSDKKDHLTVEELAQFLKVEQKMSNVTLDYCLDVIKKFEVSEENKVKNVLGIEGFTNFMRSPACDVFNPLHHEVYQDMDQPLCNYYIASSHNTYLTGDQLLSQSKVDMYARVLQEGCRCVEVDCWDGPDGEPVVHHGYTLTSKILFKDVVETINKHAFVKNEFPVILSIENHCSIQQQRKIAQYLKGIFQDKLDLSSVDTGECRQLPSPQSLKGKILVKGKKLPYHLGDDAEEGEVSDEDSADEIEDECKFKLHYSNGTTEHQVESFIRKKLDSLLKESQIRDKEDPDSFTVRALLKATHEGLNAHLKQNLDVKESGKKSHGRSLMANFGKHKKTPKSRSKSYSTDDEEDTLQNPGKEGGQLYRLGRRRRTMKLCRELSDLVVYTNSVAAQDIVDDGTTGNVLSFSETRAHQVVQQKSEQFMIYNQKQLTRIYPSAYRIDSSNFNPLPYWNAGCQLVALNYQSEGRMMQINRAKFKANGNCGYILKPQQMCKGTFNPLSGDPLPANPKKQLILKVISGQQLPKPPDSMFGDRGEIIDPFVEVEIIGLPVDCCKDQTRVVDDNGFNPVWEETLTFTVHMPEIALVRFLVWDHDPIGRDFVGQRTVTFSSLVPGYRHVYLEGLTEASIFVHITINEIFGKNRQLQGLKGLFNKNPRHGSSENNSHYVRKRSIGDRILRRTASAPAKGRKKSKVGFQEMVEIKDSVCEATRDQDGVLRRTTRSLQLRPVSMPVDKNLLGALSLPISEAAKNTDGKENYLAEDKDDGRKGPATIKDPHFSNFNKKLSSSSSALLHKDAKNQGPTASVSNPEQCGGLGLKSGRIKPHMTNDCQENRSPQNFLSPRKHLALDPATKGLQDLHGMRTDEKEQERAKGFVGRKSTQSESVLSQSSLEVENLEGSKAKGRAATSFSLSDVSALCSDIPDLHSTAILQDTEISDLINDVTLTNANESGSSISALIGQFEESNHRANVAVVSRLLSTSGTSEGVALPVALGLQTPIKNGFSQGKHKASFLCSSPELNKPSSAETTKLANNTVACGVIGSPISTPKPGDDASDKAKTRVTEDNLPDSPDAFPGQFPQSPTHGEDHRQVMSSPALSMPLAMEDTTADPALCINSEESSLVEIDGDSESLSLTACDYGEEALSQLVSPLKLQQSQETVEHIQKGLSNGYCKETLLPSEIFNNIPGVKNQSISHLTYQGAGFVYNHFSSSDAKTNQICGPQQPRAPDMHVPTPTPSTHAPLAALKLPSPCKSKSLGDLTSEDIACNFESKYQCISRSFVTNSIRDKSVTMKTKSFEPLDALTEQLRKLVSFDQEDSCQGLYSKQDVNQCPRALVRKLSSRSQSRVRNIASRAKEKQEAGKQKAMTQNPRGGVVLRSKPPAPTLAVNRHSTGSYIASYLRNMKASGLEGRGIPEGACTALRYGYMDQFCSDNSVLQTEPSSEDKPEIYFLLRL", "length": 1670 }, "evidence": [ { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GLE1-1", "protein_name": "Phosphoinositide phospholipase C", "gene_name": "Plch2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTSLSALLWLRGAASRCGKRSQPRPLLVQGSGHAEARGEAAGASLQKEYFGCGGARGGCWPRCPPGSQSLRVALARGSTSRPALRAALPGPPAPSQRGAGRGCGAGGTSDSALLARRLHGAQCHSAERAARTVRRGSPALAKRCPRSLSLSQSQATDHPSPRPRGHLAAVNAETMDAGAAPQKHMERCMSAMQEGTQMVKLRGSSKGLVRFYYLDEHRSCLRWRPSRKNEKAKISIDSIQEVSEGRQSEIFQRYPDSSFDPNCCFSIYYGSHRESLDLVSPSSEEARTWVTGLRYLMAGISDEDSLARRQRTRDQWLKQTFDEADKNGDGSLSISEVLQLLHKLNVNLPRQRVKQMFREADTDDHQGTLGFEEFCAFYKMMSTRRDLYLLMLTYSNHKDHLDASDLQRFLEVEQKMSGVTLESCQSIIEQFEPCLENKSKGVLGIDGFTNYTRSPAGDIFNPEHHRVHQDMTQPLSHYFITSSHNTYLVGDQLMSQSRVDMYAWVLQAGCRCVEVDCWDGPDGEPIVHHGYTLTSKILFKDVIETINKYAFIKNEYPVILSIENHCSVVQQKKMAQYLTDILGDKLDLSSVSGEDATMLPSPQMLKGKILVKGKKLPANISEDAEEGEVSDEDSADEIEDDCKLLNGDASTNRKRVENIAKKKLDSLIKESKIRDCEDPNDFTVSTLSPSGKLGHKAEAKKAQSKAEEDVESGEDTGVSRRNSRLLMSSFSKRKKKGSKIKKVASVEEGDESLDSPGSQSRGTARQKKTMKLSRALSDLVKYTKSVGTHDVEMEVVSSWQVSSFSETKAHQILQQKPAQYLRFNQHQLSRIYPSSYRVDSSNYNPQPFWNAGCQMVALNYQSEGRMLQLNRAKFSANGGCGYVLKPQCMCQGVFNPNSEDPLPGQLKKQLALRIISGQQLPKPRDSVLGDRGEIIDPFVEVEVIGLPVDCSKEQTRVVDDNGFNPMWEETLVFTVHMPEIALVRFLVWDHDPIGRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQTLGLKGLFLRGPKPGSLDSHAAGQPLPRPSVSQRLLRRTASAPTKSQKPSRKGFPELALGTQDAGSEGAADDVAPPSPNPALEAPTQERSGSSSPRDTRLFPLQRPISPLCSLEPIAEEPALGPGLPLQAAVPTGPSQEGPQCPVGQGAKVTGPQQTSLGASGTLQLRTGGDREKEEPPLRPHNGGIPHGPREGTSGRQTDSKSRSWAPGHLPVVRRAKSEGQVLSELSPTPAVYSDATGSDRLWQRLEPGSHRDSVSSSSSMSSNDTVIDLSLPSLGLCRSRESIPGVSLGRLTPRPCLASAARPDLPPVTKSKSNPNLRVAGGLPLAPDELQPRPLAPRLTGLHSRPPWHHLTLVGLRDCPVSAKSKSLGDLTADDFGPSFQGSTGSLSCGLSPLGVVHQVLEPGRRRDALTEQLRWLTGFQHAGDITSPTSLGPAADGSVGGPSFLRRSSSRSQSRVRAIASRARQAQERQQRLRGLDSRGPPEEERGTPEGACSVGHEGCVDVPMPAKGAPEQVCGAADDQLLLRL", "length": 1570 }, "evidence": [ { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M1PAP8-1", "protein_name": "Phosphoinositide phospholipase C", "gene_name": "plch2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDTASLNTSLFSGSMSTDSPNLSTRSMGFTTDTDSSRSSTLLHCNHFLAANYISVVEKCMSSMQTGTQMVKLRGGSKGLVRFFYLDEHKSCIRWRPSRKNEKAKISIDSIREVCEGKQSEIFQRYSDGSFDPNCCFSIYYGEHMESLDLVSGTGEEARTWITGLKYLMAGISDEDSLAKRQRTRDQWLKQTFAEADKNGDGCLSISEVLQLLHKLNVNLPRQKVKQMFKEADTDDNQGTLGFEEFCSFYKMMSTRRDLYLLMLTYSNHKDHLDTDDLKRFLETEQKMTNVSKEHCLEIVAKFEPCPENQTSGVLGIDGFTNYMRSPAGDIFNPEHYEVNQDMTQPLSDYFIASSHNTYLMGDQLMSQSRVDMYAWVLQAGCRCVEVDCWDGQDGEPIVHHGYTLTSKILFKDVIETINKYAFAKNQYPVILSIENHCSVPQQKKMAQYLTEVLGDKLDVSSIPADPSGLLPSPEALKGKILIKGKKLPSNIDENAEEGDVSDEDSADEMEDDCKLLNGDTSMNRKQAENVAKKKLDNLMKESKIRDREDPDSFTITALPPSGKHDKSPLKGKAEDSTDTGDEANIGGNKRLARTFMGSFSKRKKKTSKVKKSSSFEDTDTDQESSSGASKAQAHHSRKKKTMKLSRALSDLVYMKSVGMPDFESQGVTWQVSSMSETKAHQLIQQKPVPFMRFNQRQLSRVYPSPYRVDSSNFNPQPFWNAGCHLVALNYQSEGRVLQLNRAKFYCNGNCGYIQKPGCLCEGSFNPVAEDPLPGRLKKQLILKVISGQQLPKPKDSMLGDRGEIIDPFVEVEIIGLPVDCCKEQTRVVDDNGFNPMWEETLVFTLHMPENALIRFLVWDHDPIGQDFIGQRTIAFNSMIPGYRHVYLEGMEEASIFVHVAVNDITSKARAVSGIKGLFHRNPKQASLDSHAAALLNRKSTFGAHLLRRTASAPTKGQPKVKRGFPEISIDTKDCSSDGASEERESEEGPLVHHNGDTASAKSWGQGTNGQLHPDDRKENSEVQSPTPSLNASCLESITENFQENSPSTSTQSPVDTSPHCPLSSPSTAITASSNGENLSPVKNNEDILKSFALTQSTSGKDSGNSPVNSSISTNYLDIGCDTPTFPTFHRADGEVAQETVINQTGLTLEIDAGKEPTAIQSSQRIQALKAVFDRDIGRSMQTGLRTPVRRSKSEGQMKKADGPSVVPEVCTDATLNDRLWSKLDPSSHRDSVSSSSSISSNDTVIDLSLPNLSRKSLTCLSAARDYSDKQASLTNNHRSVIAGCGVSLVSKSKSNPNLRDGEMCNTDDDLQPRPLVADKDPIRPMQRRHTWSRLYVEGLKQSSTLAASAASKKSTTLSAKDIDSKSKSLGDLTSDDIICNFESKYRSISRSFIVRPSRQHGKTLRKPQNDFTEQLKRLTDVEPLTSKDFAQCRADSEAGQEEEEMPPLRRSSSRSQSRVRYIANRARQAQERQRLQSITRMSGSPIEERGNPEGACSVPHSPCTCLDLLSQLPPGPPQQSPLSPDNEVFFMLRL", "length": 1534 }, "evidence": [ { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1QKN6-1", "protein_name": "Phosphoinositide phospholipase C", "gene_name": "plcl1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSESYEDGVCGDGAPDFIPPRALRSGRRSGVAVPLVERDEAALLESVKAAPRRSSIIKDPSVAKVSGGRKKTVSFSSMPSEKKVSSAADCLAFMQGGCELKKVRPNSRIYSRFYTLDTELGCLRWEPSKKDGDRARLDISAIREVRTGKSTETFIHNGPLDNLAEEAAFSIIHGDDYQSLDLVALSADVANIWVTGMRYLLSHPGAIGGGIGGDGGVGEGSIGSKMRRNWLVAEFALVDEDGHGIVSEDTAVATICKLCPGIKEAKVRLRFKEIQRSKEKLTSHVTLEEFQEAYCELCTRPDVYFLLVQLSKDRECLDAQDLRLFLESEQGLSMATTEGCLELLRLFEPSAAGRERGLLGLDGFARYLQSAECQLLDPEHQNVCQDMKMPLSHYFISASYRSYLLDDQVHGRADLGGLTRALQAGCRCLELGVTDGPEGEPLLGVDHGAEVKHHHHHHHHHHHHHGSVTLRSALEVVNKYAFLTSQYPLLLYLCQRCSPSQQRTLAQHLKKVFGPKLYTPESLPVSLGGRATTLPSPEQLKGKVLLVGKKLPPEEEGSEGEVSEEDEEIGGGGPLAGRRMTIPGEEELGVVLVVPPPPQPRRLRLRHELSDLVAVARTGSRNFYAHRASILPSQQHSPPSTPSTPGTPLNIDPSYWTLCSLGEGEAGRLASESPEELVSFTKRNLTRVRPSSVRLDSSNPNPQGYWKGGVQLVALNQQTPGAMLDLNRGRFMQNGGCGYVLRPAVMREEVSYFSAQSQGCVPGVPPQTLRVKVISAHSLPKPQGSGAKGEVIDPYVVLELHGVPADCTEQRTRTAAQNQDDPLFDETFEFQVNMPELALLRFVVLDDDYIGDDFIGQYTIAFECLQPGYRNVPLLGLAGDPLPHASLFIHIAITNRRGGGKAQRRGLSVRRGVRRGREYVTLRNTGIKVLDDTFRPASGPLREATDLREDAMCATVAFKELCGLPPMATLKQCIQSLATRLQSPDGPPGATLTLKDGYPFLEPAANLTDATRKLLNGYDTMISANKQLIENADGVQEKIAQVQKEGMVFHEDLPRLGEKENLKGRKQSKAVESFAWNITVLKGQCDLLRSAKIDALDTLRQLALACEASGLIVTSDGQYTSHGLSSRRGSSHGNGRI", "length": 1137 }, "evidence": [ { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M2BAJ8-1", "protein_name": "Phosphoinositide phospholipase C", "gene_name": "plcd1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MQCIRRQPTRTKSQESLYRAHIKTIARDNMKLLVLEGDRDLQFLMNGGDLLKVRSESWKKTRYFKLQEDCKTMWHESKKTLKTKQTFSIEDIEEVRTGRQTDSLRKYTEETLEGRAFSILFKGRQKSLDLIASTEEEAKKWVSGLEKVISSLNNLSSQKKTEHWIYSSLRKADKNLDNKMSLKEVKSFLKDINVEVHEDYAEMLFKECDKSNGGFLEGNEIEHFYKILTKREEIDVIYGEYAKTDGLMSANDLLNFLLTEQREEVSQNDALQLIEKYELDENAKAKQQMTQDGFLMYLHQPEGLIFNQAHKSVYHDMNQPLSHYFISSSHNTYLMEDQLKGPSSTEAYIRALLKGCRCVELDCWDGSDGEPVIYHGYTLTSKILFKDVIKAIKEYAFKTSEYPVILSLENHCGVEQQKIMAQHLTSILGSALVTKPLGDQMPTCLPAPEELKGRFIVKGKRLDKLENAFSDESKMADEESVSEEEDDEGDEENNEKKSGSLKLAKELSDIVIYCKSVPFHGLEDSREKHSFYEMASFKEGKALKLAEESATEYIRHNTDKLSRIYPGGMRTDSSNYNPVPMWNAGCQIVALNFQTPCLEMDLNQGLFYQNGRSGYILKPSYLRERDTEFDPITLTKGPWLKRKTLHVMVISAQQLPKVGKRESAIVDPIVKVQVYGVPADTAAVETSYIKNNGFNPMWNENFQLEVCVPDLALVRFLIEDYDSTSDNEFIGQYTLPFNSLRNGYHHVPLLTQDGNLLSSAGLFVHIMVVDTE", "length": 772 }, "evidence": [ { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PL02-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase", "gene_name": "plcb4a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MYFCVSPQPHSGESQTDYINSSTAGQMAKPYEFNWQRPVPQFMQKGACFDRFDEDPLVFESNCFFKVDESGFFLTWKSEGKEGQVLEFSLINSIRDASALKDPKVLCALEASGKCESNLEDRIICICSGTDLVNLSFMYMVTQNPTTAKEWTDGLRSLIQNTRANNVCPMTCLRKHWMRLSFLTNVNEQIPVRSITRTFASGKTEKGIFQALKDLGLPSGKNDEIQREIFTFDKFYSLTQKICPRTDIEVLFKKFKGDKGDYLSVEQFVHFLNDNQRDPRLNEILFPFFNSKCAFQIIQRYEPDEKLKRKGLLSCDGFCRFLMSDENAPVFLDRLEVYQEMDHPLSHYFINSSHNTYLTGRQFGGKSSVEIYRQVLLTGCRCVELDCWDGKGEDQEPIITHGKAMCTDVLFKDVIQGIKETAFLTSEYPVILSFENHCTKHQQYKLARYCEDIFGDLLLKQPLEDFPMEPGCPLPSPNDLKGKILIKNRRLKPEVEKKQLEDFRKHMEAGEPSVSTNLFEDENEDETNTAELLNEAHPERIHGCLITEEENREEEVLLRHRKAEEENVADELAVIQSYTYVAATTNIHPYLSNIINYAQAVKFTGFDEAEEKNIHHNMSSFNESVGLGYLRTNAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNFQTPDLAMQLNQGKFEYNGSCGFLLKPDFMRRPDRMFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNAEAFVFRKVILPDLAVLRVAVYDDNNKLIGQRILPLDGLQSGYRHISLRNEYNKPLPLATVFCNIILKTYVPDGFGAIVDALSDPKKFLSICEKRTDQMRAMGIETSDIADVPSDVWKGNKKRKTNQAGMMMKPQKDSDRPRENMPISSKEDSSVLTPQLTIDDLKQTKTFLKLIKKQQKEVNALKKKHAKAQHALRSSHSAQLDKTVAQHEKEKHTLEKQLHKNTSRKVSESSSLEMSRDIEQQMKTAVMNHKSKVKDMASAQASECSEMLRWHSAEEQTVVEQHLLQQCEQLHKLLMLEQEQQTHQLTLLHERQSKEMRTNQAKTSMESSKAISQDKSIKNKAERERRVRELNSTNTRKFLTERKRLAMKQTKECEQLQAAQREQLERLEKHNEELSNSCYAKSQCQGQNEAVCGDMREDEPLTGQTHMSLQ", "length": 1213 }, "evidence": [ { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PVI9-1", "protein_name": "Phosphoinositide phospholipase C", "gene_name": "plch2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNSSPAMAPSSPVLFSPSLARRPPSPGRRPNTNFRSASPSIMTSPKLWQKAAISRLAEEFFWIGGSIVASPKWRMGQIVERCMCNMQAGSQMIKLRGKSKALVRLFYLDEHKSCIRWRPSRKHERAKITIDSIHEVCEGMRTEVFRRFANNNFDPNCCFSIYHGDHVESLDLVSTNGEEARTWITGLKYLLAGISDEDSLAKRQRTRDQWLRQTFSEADKNGDGNLSIGEVLQLLHKLNVNLPKQKVREMFQEADTDENQGSLTFEEFCTFYKLISTRRDLYLLMISYSNHKEHLDLNDLQRFLESEQKMVNVTKEYCKMIINQFEPCSQNQSHVVLGIDGFTNYMRSPAGDIFNPEHYQVNQDMTQPLTNYYIASSHNTYLTGDQLLSQSRVDMYAYVLQMGCRCVEVDCWDGPDGEPIVHHGYTLTSKILFKDVVETINKYAFAKTQFPVILSIENHCTVPQQKKMAQYLMEVLQDKVDLSNINTNESRRLPSPEDLKGKILVKGKKLPANIDADADEGDVSDEDSGEEDEEEELQLNGDTTEGAPESASADESKKRSRRKFMGSFRRKKKKQVKVKKKPIVSDSDTEPEITSTNDKQVINYGKRRKTMRLSRALSDLVKYTKSVRVHDIETQAYMSSWQVSSLNESITNQILQLKPAQLVRFNQRQLLRVYPSNYRVDSSNFNPQPFWNAGCHLVALNYQTEGRMLQLNRAKFAANGNCGYVLKPKCMCKGAFNPVLEDPLPGHRKSQLVLKIISGQQLPKPKDSMLGDRGEIIDPFVEVEIIGLPIDCNKQQTRVVDDNGFNPTWEETLVFTLHMPQIALVRFMVWDHDPIGRDFIGQRTISFKSMMPGYRHVYLEGMEEASIFVHVAVNDITGKVKSSNAVKQLIQKNLMQTSEDGTRKSFAPNFLRKSGKNQSKVVKVECYTKEDFLNRRYSDDVSSKDSRSTSQSASLLRGAQSEPLKRAHRVSFQEPEGSHEPRRRLSSIPYTGGAAVDYTNLAFDSHSSSELDIQTFSHLEDNTESKQNDSLSSKLEFESTDIPKSPASTLNEQCLSRQISAANEHSEQKPEMSKMIHSVPDPLNFHPIPDGVLDPSRGTLNTLVPQNKFRSSLDARLNPRWQPLSIPATPALNRRMNDKGTPNSLLKGCRSQSVPRRRPTSPPNTPGHIRRDPINQYFLPQCSYTTANDLVPNNHNIAESESSSLSSLDSLDLSTLPCRFPDNQQQTMGTLQREMNALFEQKIQEIRCHSPLFFRDSSTL", "length": 1260 }, "evidence": [ { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABK0LMR7-1", "protein_name": "Phosphoinositide phospholipase C", "gene_name": "Plcd3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLCGGWRRSRRSPEEPRVSAQVAAPLAFLPSPASSDSSTKRPGLRALKKMGLTEDEDVQAMLRGSKLLKIRSRTWHKERLYRLQEDGLSVWFQRRIPRAASQHIFFVQHIEAVREGHQSEGLRRFGGAFAPARCLTIAFKGRRKNLDLAAPTAEEAQRWVRGLAKLRARLDAMSQRERLDHWIHSYLHRADSDQDSKMSFKEIKSLLRMVNVDMNDMYAYRLFKECDHSNNERLEGAEIEAFLRRLLKRPELEEIFRRYSGEDRVLSASELLEFLEDQGEDGATLACAQKLIQTYELNETAKQHELMTLDGFMMYLLSPEGAALNVAHTCVFQDMGQPLAHYFISSSHNTYLTDSQIGGTSSTEAYIRAFTQGCRCVELDCWEGPGGEPVIYHGHTLTSKILFRDVIQAVRDHAFTLSPYPVILSLENHCGLEQQIVMARHLRNILGDMLVTQALDSQNPEELPSPEQLKCRVLVKGKKLPAARNEDGRILSDREDEDEDEEEAEEALETAEQRKRAKQISPELSALVVYCCATRLRTLEPSPGPPQPCKIGSLSERKARKFTREAGTSFVRHNTQQLTRVYPLGLRMTSANYNPQEMWNSGCQLVALNFQTPGYEMDLNTGRFLINGQCGYVLKPAYLRQLNTTFDPECPGPPRTTLTVQVLTAQQLPKLNVEKPNSIVDPLVRVEIYGVPEDCAHKETDYVLNNGFNPCWEQTLQFQLRAPELVLVRFVVEDYDTTSPNDFVGQFTLPLNSLKQGYRHIHLLSKDGASLSPATLFVHIRIENS", "length": 785 }, "evidence": [ { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A2AP18-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2", "gene_name": "Plch2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGGLAWGPSRAAGSSWVNASGTWEQPLRGFSGLQGGRRRGRGEKGIPEEPLCQLTPQLGLSLRVPFGLGDYGLDMPGPQPSAASQTTGAVACLAEVLLWVGGSVVVSPRWQLSLVVERCMSAMQEGTQMVKLRGSSKGLVRFYYLDEHRSCLRWRPSRKNEKAKISIDSIQEVSEGRQSEIFQRYPDSSFDPNCCFSIYHGSHRESLDLVSPSSEEARTWVTGLRYLMAGISDEDSLARRQRTRDQWLKQTFDEADKNGDGSLSISEVLQLLHKLNVNLPRQRVKQMFREADTDDHQGTLGFEEFCAFYKMMSTRRDLYLLMLTYSNHKDHLDASDLQRFLEVEQKMNGVTLESCQNIIEQFEPCLENKSKGMLGIDGFTNYTRSPAGDIFNPEHNRVHQDMTQPLSHYFITSSHNTYLVGDQLMSQSRVDMYAWVLQAGCRCVEVDCWDGPDGEPIVHHGYTLTSKILFKDVIETINKYAFIKNEYPVILSIENHCSVVQQKKMAQYLTDILGDKLDLSSVSSEDATMLPSPQMLKGKILVKGKKLPANISEDAEEGEVSDEDSADEMEDDCKLLNGDASTNRKRVENIAKKKLDSLIKESKIRDCEDPNDFSVSTLSPSGKLGRKAEAKKGQSKVEEDVEAGEDSGVSRQNSRLFMSSFSKRKKKGSKIKKVASVEEGDETLDSPGSQSRGTARQKKTMKLSRALSDLVKYTKSVGTHDVEIEVVSSWQVSSFSETKAHQILQQKPTQYLRFNQHQLSRIYPSSYRVDSSNYNPQPFWNAGCQMVALNYQSEGRMLQLNRAKFSANGDCGYVLKPQCMCQGVFNPNSEDPLPGQLKKQLALRIISGQQLPKPRDSVLGDRGEIIDPFVEVEVIGLPVDCSKEQTRVVDDNGFNPMWEETLVFTVHMPEIALVRFLVWDHDPIGRDFIGQRTLAFSSIMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQTLGLKGLFLRGTKPGSLDSHAAGQPLPRPSVSQRLLRRTASAPTKSQKPSRKGFPELALGTQDAGSEGAADDVAPSSPNPALEAPTQERSGSSSPRDTRLFPLQRPISPLCSLEPIAEEPALGPGLPLQAAAPTGPSQEGSQCPVGLGAKVTSSQQTSLGAFGTLQLRIGGGRENEEPPLRPHNGGISSGPREGTSGRQTDSKSRSRVPGHLPVVRRAKSEGQVLSELSPTPAVYSDATGTDRLWQRLEPGSHRDSVSSSSSMSSNDTVIDLSLPSLGLCRSRESIPGVSLGRLTSRPCLASAARPDLPPVTKSKSNPNLRVAGGLPTAPDELQPRPLAPRLTGHHPRPPWHHLTLVGLRDCPVSAKSKSLGDLTADDFAPSFQGSTSSLSCGLGSLGVAHQVLEPGIRRDALTEQLRWLTGFQQAGDITSPTSLGPAGDGSVGGPSFLRRSSSRSQSRVRAIASRARQAQERQQRLRGQDSRGPPEEERGTPEGACSVGHEGCVDVPMPAKGAPEQVCGAADGQLLLRL", "length": 1501 }, "evidence": [ { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A3KGF7-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2", "gene_name": "Plcb2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSLLNPVLLPPNVKAYLSQGERFIKWDDETSIASPVILRVDPKGYYLYWTYQNQEMEFLDVTSIRDTRFGKFAKIPKSQKLREVFNMDFPDNHFLLKTLTVVSGPDMVDLTFYNFVSYKENVGKDWAEDVLALAKHPMTVNAPRSTFLDKILVKLKMQLNPEGKIPVKNFFQMFPADRKRVEAALGACHLAKGKNDAINPEDFPESVYKSFLMSLCPRPEIDEIFTSYHSKAKPYMTKEHLTKFINQKQRDPRLNSLLFPPARPEQVQVLIDKYEPSGINVQRGQLSPEGMVWFLCGPENSVLAHDTLLIHQDMTQPLNHYFINSSHNTYLTAGQFSGLSSAEMYRQVLLSGCRCVELDCWKGKPPDEEPIITHGFTMTTDILFKEAIEAIAESAFKTSPYPVILSFENHVDSPRQQAKMAEYCRSMFGETLLTDPLENFPLKPGIPLPSPEDLRGKILIKNKKNQFSGPASPSKKPGGVAEGSLPSSVPVEEDTGWTAEDRTEVEEEEVVEEEEEEESGNLDEEEIKKMQSDEGTAGLEVTAYEEMSSLVNYIQPTKFISFEFSAQKNRSYVVSSFTELKAYELLSKASMQFVDYNKRQMSRVYPKGTRMDSSNYMPQMFWNAGCQMVALNFQTMDLPMQQNMALFEFNGQSGYLLKHEFMRRLDKQFNPFSVDRIDVVVATTLSITIISGQFLSERSVRTYVEVELFGLPGDPKRRYRTKLSPTANSINPVWKEEPFIFEKILMPELASLRIAVMEEGSKFLGHRIIPINALHSGYHHLCLRSESNMALTMPALFVFLEMKDYIPDTWADLTVALANPIKYFNAQDKKSVKLKGVTGSLPEKLFSGTPVASQSNGAPVSAGNGSTAPGTKATGEEATKEVTEPQTASLEELRELKGVVKLQRRHEKELRELERRGARRWEELLQRGAAQLAELQTQAAGCKLRPGKGSRKKRTLPCEETVVAPSEPHDRADPRVQELKDRLEQELQQQGEEQYRSVLKRKEQHVTEQIAKMMELAREKQAAELKTFKETSETDTKEMKKKLEAKRLERIQAMTKVTTDKVAQERLKREINNSHIQEVVQAVKQMTETLERHQEKLEERQTACLEQIQAMEKQFQEKALAEYEAKMKGLEAEVKESVRAYFKDCFPTEAEDKPERSCEASEESCPQEPLVSKADTQESRL", "length": 1181 }, "evidence": [ { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A5D6R3-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3-A", "gene_name": "plcd3a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLGRKKNPETVQTESKSVESKTHDPLRRLGVLDDEDVLLMLQGSKMMKVRSQRWRKDRRLKLLEDCVTVWCESSKTSRKSNRQQTFSVTEVECVREGCQSECLRRMTDLVPEKNCFTVVFRGGRKSLDLCCHTQEEAERWVRGIRTLKDRVSNMSQKEKLDHWIRGYLRRADQNQDGKMSYDEVKHLLQLINIDLNEQYARTLFKKCDRSCDGRLDHVEIEEFCREMMRRPELDAVFRHYSGNGCVLTTLELRDFLGDQGEDASLVHAKSLIQTFELNDWAQKNLFMTQNGFTMYMLSKENDVFNPDHTHVYQDMSKPLAHYYISSSHNTYLTKDQVTSASSTEPYIRALNQGCRCVELDCWDGDKGEPIIYHGHTLTSKVLFKEVIETIAQYAFKASPYPLILSLENHCSVEQQAIMAQQLQSILGKKLLAKPLSDLPLKQLPSPEELKGRILLKGKKLNGLLGKTESWTSFTNSSDEESVAGGNKKESKKDLARSASTKLSPELSDLVVYCQSVPFSGFETANQRPPSVITSFSENEALKLIKDSGKLFVRNNSRQLSRIYPSAQRLQSSNFDPQDMWNAGCQMVALNFQTPGEQMDLNQGRFLPNGRCGYVLKPEFLCDPKSDFDPENTGGGPGHIPTQLTIRVISAQQLPKINTDKPNSIVDPQVWVEIHGVSIDKARAKTQRIDNNGFNPRWDCTVSFQLQLPELALVRFMVEDHDHKSKNDFIGQFTLPFTSLRTGYRHVHLLKADGSTLSPATLFIHVKVVRRGVHIKTVSERIGKA", "length": 784 }, "evidence": [ { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1M324-1", "protein_name": "Phosphoinositide phospholipase C", "gene_name": "Plcl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAECGRGAAGGALPTSPGPALGAKGALKAGAGEGGGSGGGGRLGHGRARYDSGGVSNGDCSLGVSGDEARASPARGPRGVALARTPSPAAGPVPRDSKPGGLPRRSSIIKDGTKQKRERKKTVSFSSMPTEKKISSASDCINSMVEGSELKKVRSNSRIYHRYFLLDADMQSLRWEPSKKDSEKAKIDIKSIKEVRTGKNTDIFRSNGISEQISEDCAFSVIYGENYESLDLVANSADVANIWVTGLRYLISYGKHTLDMLESSQDNMRTCWVSQMFSEIDVDDLGHITLCNAVQCIRNLNPGLKTSKIELKFKELHKSKDKTGTEITKEEFVEVFHELCTRPEIYFLLVQFSSNKEFLDTKDLMMFLEAEQGVAHINEEISLEIIHKYEPSKEGQEKGWLSIDGFTNYLMSPDCYIFDPEHKKVCQDMKQPLSHYFINSSHNTYLIEDQFRGPSDITGYIRALKMGCRSVELDVWDGPDNEPVIYTGHTMTSQIVFRSVIDIINKYAFFASEYPLILCLENHCSIKQQKVMVQHMKKILGDKLYTTSPNMEESYLPSPDVLKGKILIKAKKLSSNCSGVEGDVTDEDEGAEMSQRMGKENVEQPNHVPVKRFQLCKDLSELVSICKSVQFKEFQVSFQVQKYWEVCSFNEVLASKYANENPGDFVNYNKRFLARVFPSPMRIDSSNMNPQDFWKCGCQIVAMNFQTPGLMMDLNIGWFRQNGNCGYVLRPAIMREEVSFFSANTKDSVPGVSPQLLHIKIISGQNFPKPKGSGAKGDVVDPYVYVEIHGIPADCAEQRTKTVNQNGDAPMFDESFEFQINLPELAMVRFVVLDDDYIGDEFIGQYTIPFECLQTGYRHVPLQSLTGEVLAHASLFVHVAITNRRGGGKPHKRGLSVRKGKKSREYASLRTLWIKTVDEVFKNAQPPIRDATDLRENMQNAVVSFKELCGLSSVANLMQCMLAVSPRFLGPDNTPLVVLNLSEPYPTMELQAIVPEVLKKIVTTYDMMIQSLKALIENADAVYEKIVHCQKAAMEFHEHLHSIGTKEGLKERKLQKAVESFTWNITILKGQADLLKYAKNETLENLKQIHYAAVSCGLNKPGTENSEAQKPRRSLEVIPEKTSDENGD", "length": 1128 }, "evidence": [ { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SDV6-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma", "gene_name": "PLCG1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGAASPCANGCGPGAPSDAEVLHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQITWSRGADKIEGAIDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHCFVILYGMEFRLKTLSLQATSEDEVNMWIKGLTWLMEDTLQAATPLQIERWLRKQFYSVDRNREDRISAKDLKNMLSQVNYRVPNMRFLRERLTELEQRSSDITYGQFAQLYRSLMYSAQKTMDLPFLEASTLRAGERPELCRVSLPEFQQFLLEYQGELWAVDRLQVQEFMLSFLRDPLREIEETYFFLDEFVTFLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMGCRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIAQQRNMAQYFKKVLGDTLLTKPVDIAADGLPSPNQLKRKILIKHKKLAEGSAYEEVPTSVMYSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPKEASSSTELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMRLSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQEGQTVMLGNSEFDSLVDLVSYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYGALYEGRNPGFYVEANPMPTFKCAVKALFDYKAQRDDELTFTKSAIIQNVEKQEGGWWRGDYGGKKQLWFPSNYVEEMVSPAALEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKNNRLFVFSISMASVAHWSLDVAADSQEELQDWVKKIREVAQTADARLTEGKMMERRKKIALELSELVVYCRPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRIYPKGQRLDSSNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFMAGGHCGYVLQPSTMRDEAFDPFDKSSLRGLEPCAICVEVLGARHLPKNGRGIVCPFVEIEVAGAEYDSIKQKTEFVVDNGLNPVWPAKLFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAVPLKNNYSEDLELASLLIKLDIFPVKQENSDLSPFGGTSLRERGYDISGQPAHGRAREGSFEARYQQPFEDFRISQEHLADHFDSRERRAPRRTRVNGDNRL", "length": 1291 }, "evidence": [ { "id": "Q9VXH3", "url": "https://omabrowser.org/oma/group/Q9VXH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O75038-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2", "gene_name": "PLCH2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSGPWPSPDSRTKGTVAWLAEVLLWVGGSVVLSSEWQLGPLVERCMGAMQEGMQMVKLRGGSKGLVRFYYLDEHRSCIRWRPSRKNEKAKISIDSIQEVSEGRQSEVFQRYPDGSFDPNCCFSIYHGSHRESLDLVSTSSEVARTWVTGLRYLMAGISDEDSLARRQRTRDQWLKQTFDEADKNGDGSLSIGEVLQLLHKLNVNLPRQRVKQMFREADTDDHQGTLGFEEFCAFYKMMSTRRDLYLLMLTYSNHKDHLDAASLQRFLQVEQKMAGVTLESCQDIIEQFEPCPENKSKGLLGIDGFTNYTRSPAGDIFNPEHHHVHQDMTQPLSHYFITSSHNTYLVGDQLMSQSRVDMYAWVLQAGCRCVEVDCWDGPDGEPIVHHGYTLTSKILFKDVIETINKYAFIKNEYPVILSIENHCSVIQQKKMAQYLTDILGDKLDLSSVSSEDATTLPSPQMLKGKILVKGKKLPANISEDAEEGEVSDEDSADEIDDDCKLLNGDASTNRKRVENTAKRKLDSLIKESKIRDCEDPNNFSVSTLSPSGKLGRKSKAEEDVESGEDAGASRRNGRLVVGSFSRRKKKGSKLKKAASVEEGDEGQDSPGGQSRGATRQKKTMKLSRALSDLVKYTKSVATHDIEMEAASSWQVSSFSETKAHQILQQKPAQYLRFNQQQLSRIYPSSYRVDSSNYNPQPFWNAGCQMVALNYQSEGRMLQLNRAKFSANGGCGYVLKPGCMCQGVFNPNSEDPLPGQLKKQLVLRIISGQQLPKPRDSMLGDRGEIIDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDHDPIGRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQALGLKGLFLRGPKPGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGVADDVVPPGPGPAPEAPAQEGPGSGSPRDTRPLSTQRPLPPLCSLETIAEEPAPGPGPPPPAAVPTSSSQGRPPYPTGPGANVASPLEDTEEPRDSRPRPCNGEGAGGAYERAPGSQTDGRSQPRTLGHLPVIRRVKSEGQVPTEPLGGWRPLAAPFPAPAVYSDATGSDPLWQRLEPCGHRDSVSSSSSMSSSDTVIDLSLPSLGLGRSRENLAGAHMGRLPPRPHSASAARPDLPPVTKSKSNPNLRATGQRPPIPDELQPRSLAPRMAGLPFRPPWGCLSLVGVQDCPVAAKSKSLGDLTADDFAPSFEGGSRRLSHSLGLPGGTRRVSGPGVRRDTLTEQLRWLTVFQQAGDITSPTSLGPAGEGVAGGPGFVRRSSSRSHSRVRAIASRARQAQERQQRLQGLGRQGPPEEERGTPEGACSVGHEGSVDAPAPSKGALGPASAAAENLVLLRL", "length": 1416 }, "evidence": [ { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O89040-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2", "gene_name": "Plcb2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLLNPVLLPPKVKAYLSQGERFIKWDDETSIASPVILRVDPKGYYLYWTHQSKEMEFLDVTSIRDTRFGKFAKIPKSQKLREVFNMDFPDNHFLLKTFTVVSGPDMVGLTFHNFVSYKENVGKDWAEDVLALAKHPMTANASRSTFLDKILVKLKMQLSPEGKIPVKNFFQMFPADRKRVEAALSACHLAKGKNDAINPEDFPESVYKSFLMSLCPRPEIDEIFTSYHAKAKPYMTKEHLTKFINQKQRDPRLNSLLFPPARPEQVQALIDKYEPSGINVQRGQLSPEGMVWFLCGPENSVLAHDTLRIHQDMTQPLNHYFINSSHNTYLTAGQFSGPSSAEMYRQVLLSGCRCVELDCWKGKPPDEEPIITHGFTMTTDILFKEAVEAIAESAFKTSPYPVILSFENHVDSPRQQAKMAEYCRTMFGETLLTEPLENFPLKPGMPLPSPEDLRGKILIKNKKNQFSGPASPNKKPDGVSEGGFPSSVPVEEDTGWTAEDRTEVEEGEEEEEVEEEEEEESGNLDEEEIKKMQSDEGTAGLEVTAYEEMSSLVNYIQPTKFISFEFSAQKNRSYLVSSFTELKAYELLSKASMQFVDYNKRQMSRVYPKGTRMDSSNYMPQMFWNAGCQMVALNFQTMDLPMQQNMALFEFNGQSGYLLKHEFMRRQDKQFNPFSVDRIDVVVATTLSITVISGQFLSERSVRTYVEVELFGLPGDPKRRYRTKLSPTANSINPVWKEEPFIFEKILVPELASLRIAVMEEGGKFIGHRIIPINALHSGYHHLCLRSESNMPLTMPALFVFLEMKDYVPDTWADLTVALANPIKYFSAHDKKSVKLKEVTGSLPEKLFSGIPVASQSNGAPVSAGNGSTAPGTKAKEEATKEVAEPQTTSLEELRELKGVVKLQRRHEKELRELERRGARRWEELLQRGAAQLAELQDPAASCKLRPGKGSRKKRIVPCEETIVVPREVLEGPDPRVQDLKDRLEQELQQQGEEQYRSVLKRKEQHVTEQIAKMMELAREKQAAELKSFKETSETDTKEMKKKLEAKRLERIQAMTKVTTDKVAQERLKREINNSHIQEVVQAVKQMTETLERHQEKLEEKQTACLEQIQAMEKQFQEKALAEYEAKMKGLEAEVKESMRACFKACFPTEAEEKPERPCEASEESCPQEPLVNKTDTQESRL", "length": 1183 }, "evidence": [ { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P10686-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "gene_name": "Plcg1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGVGTPCANGCGPSAPSEAEVLHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQITWSRGADKIEGSIDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHCFVILYGMEFRLKTLSLQATSEDEVNMWIKGLTWLMEDTLQAATPLQIERWLRKQFYSVDRNREDRISAKDLKNMLSQVNYRVPNMRFLRERLTDFEQRSGDITYGQFAQLYRSLMYSAQKTMDLPFLETNTLRTGERPELCQVSLSEFQQFLLEYQGELWAVDRLQVQEFMLSFLRDPLREIEEPYFFLDELVTFLFSKENSVWNSQLDAVCPETMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMGCRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIAQQRNMAQHFRKVLGDTLLTKPVDIAADGLPSPNQLKRKILIKHKKLAEGSAYEEVPTSVMYSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPKEASGSTELHSSEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMRLSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYGALYEGRNPGFYVEANPMPTFKCAVKALFDYKAQREDELTFTKSAIIQNVEKQDGGWWRGDYGGKKQLWFPSNYVEEMINPAILEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKNNRLFVFSISMPSVAQWSLDVAADSQEELQDWVKKIREVAQTADARLTEGKMMERRKKIALELSELVVYCRPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRIYPKGQRLDSSNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFMAGGHCGYVLQPSTMRDEAFDPFDKSSLRGLEPCVICIEVLGARHLPKNGRGIVCPFVEIEVAGAEYDSTKQKTEFVVDNGLNPVWPAKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAVPLKNNYSEDLELASLLIKIDIFPAKENGDLSPFSGTSLRERASDASSQLFHVRAREGSFEARYQQPFEDFRISQEHLADHFDSRERRAPRRTRVNGDNRL", "length": 1290 }, "evidence": [ { "id": "RGD:3347", "url": "https://alliancegenome.org/gene/RGD:3347#orthology", "database": "AGR" }, { "id": "MGI:97615", "url": "https://alliancegenome.org/gene/MGI:97615#orthology", "database": "AGR" }, { "id": "HGNC:9065", "url": "https://alliancegenome.org/gene/HGNC:9065#orthology", "database": "AGR" }, { "id": "FB:FBgn0003416", "url": "https://alliancegenome.org/gene/FB:FBgn0003416#orthology", "database": "AGR" }, { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" }, { "id": "Q9VXH3", "url": "https://omabrowser.org/oma/group/Q9VXH3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P10687-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1", "gene_name": "Plcb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGAQPGVHALQLKPVCVSDSLKKGTKFVKWDDDSTIVTPIILRTDPQGFFFYWTDQNKETELLDLSLVKDARCGKHAKAPKDPKLRELLDVGNIGHLEQRMITVVYGPDLVNISHLNLVAFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSADRKRVETALEACSLPSSRNDSIPQEDFTPDVYRVFLNNLCPRPEIDNIFSEFGAKSKPYLTVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNSSLAKKGQMSVDGFMRYLSGEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKKKLSEQASNTYSDSSSVFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEMSNLVNYIQPVKFESFETSKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTVDLAMQINMGMYEYNGKSGYRLKPEFMRRPDKHFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQGNAVNPVWEEEPIVFKKVVLPSLACLRIAAYEEGGKFIGHRILPVQAIRPGYHYICLRNERNQPLMLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKKEADPGETSSEAPSETRTTPAENGVNHTATLAPKPPSQAPHSQPAPGSVKAPAKTEDLIQSVLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTELIKEHTTKYNEIQNDYLRRRAALEKSAKKDSKKKSEPSSPDHGSSAIEQDLAALDAEMTQKLIDLKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKITEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKPKLQMELEQEYQDKFKRLPLEILEFVQEAMKGKVSEDSNHGSAPPSLASDPAKVNLKSPSSEEVQGENAGREFDTPL", "length": 1216 }, "evidence": [ { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P10688-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1", "gene_name": "Plcd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSGRDFLTLHGLQDDPDLQALLKGSQLLKVKSSSWRRERFYKLQEDCKTIWQESRKVMRSPESQLFSIEDIQEVRMGHRTEGLEKFARDIPEDRCFSIVFKDQRNTLDLIAPSPADAQHWVQGLRKIIHHSGSMDQRQKLQHWIHSCLRKADKNKDNKMNFKELKDFLKELNIQVDDGYARKIFRECDHSQTDSLEDEEIETFYKMLTQRAEIDRAFEEAAGSAETLSVERLVTFLQHQQREEEAGPALALSLIERYEPSETAKAQRQMTKDGFLMYLLSADGNAFSLAHRRVYQDMDQPLSHYLVSSSHNTYLLEDQLTGPSSTEAYIRALCKGCRCLELDCWDGPNQEPIIYHGYTFTSKILFCDVLRAIRDYAFKASPYPVILSLENHCSLEQQRVMARHLRAILGPILLDQPLDGVTTSLPSPEQLKGKILLKGKKLGGLLPAGGENGSEATDVSDEVEAAEMEDEAVRSQVQHKPKEDKLKLVPELSDMIIYCKSVHFGGFSSPGTSGQAFYEMASFSESRALRLLQESGNGFVRHNVSCLSRIYPAGWRTDSSNYSPVEMWNGGCQIVALNFQTPGPEMDVYLGCFQDNGGCGYVLKPAFLRDPNTTFNSRALTQGPWWRPERLRVRIISGQQLPKVNKNKNSIVDPKVIVEIHGVGRDTGSRQTAVITNNGFNPRWDMEFEFEVTVPDLALVRFMVEDYDSSSKNDFIGQSTIPWNSLKQGYRHVHLLSKNGDQHPSATLFVKISIQD", "length": 756 }, "evidence": [ { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P13217-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase", "gene_name": "norpA", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTKKYEFDWIIPVPPELTTGCVFDRWFENEKETKENDFERDALFKVDEYGFFLYWKSEGRDGDVIELCQVSDIRAGGTPKDPKILDKVTKKNGTNIPELDKRSLTICSNTDYINITYHHVICPDAATAKSWQKNLRLITHNNRATNVCPRVNLMKHWMRLSYCVEKSGKIPVKTLAKTFASGKTEKLVYTCIKDAGLPDDKNATMTKEQFTFDKFYALYHKVCPRNDIEELFTSITKGKQDFISLEQFIQFMNDKQRDPRMNEILYPLYEEKRCTEIINDYELDEEKKKNVQMSLDGFKRYLMSDENAPVFLDRLDFYMEMDQPLAHYYINSSHNTYLSGRQIGGKSSVEMYRQTLLAGCRCVELDCWNGKGEDEEPIVTHGHAYCTEILFKDCIQAIADCAFVSSEYPVILSFENHCNRAQQYKLAKYCDDFFGDLLLKEPLPDHPLDPGLPLPPPCKLKRKILIKNKRMKPEVEKVELELWLKGELKTDDDPEEDASAGKPPEAAAAPAPAPEAAAAAEGAAEGGGGAEAEAAAANYSGSTTNVHPWLSSMVNYAQPIKFQGFDKAIEKNIAHNMSSFAESAGMNYLKQSSIDFVNYNKRQMSRIYPKGTRADSSNYMPQVFWNAGCQMVSLNFQSSDLPMQLNQGKFEYNGGCGYLLKPDFMRRADKDFDPFADAPVDGVIAAQCSVKVIAGQFLSDKKVGTYVEVDMFGLPSDTVKKEFRTRLVANNGLNPVYNEDPFVFRKVVLPDLAVLRFGVYEESGKILGQRILPLDGLQAGYRHVSLRTEANFPMSLPMLFVNIELKIYVPDGFEDFMAMLSDPRGFAGAAKQQNEQMKALGIEEQSGGAARDAGKAKEEEKKEPPLVFEPVTLESLRQEKGFQKVGKKQIKELDTLRKKHAKERTSVQKTQNAAIDKLIKGKSKDDIRNDANIKNSINDQTKQWTDMIARHRKEEWDMLRQHVQDSQDAMKALMLTVQAAQIKQLEDRHARDIKDLNAKQAKMSADTAKEVQNDKTLKTKNEKDRRLREKRQNNVKRFMEEKKQIGVKQGRAMEKLKLAHSKQIEEFSTDVQKLMDMYKIEEEAYKTQGKTEFYA", "length": 1095 }, "evidence": [ { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P16885-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2", "gene_name": "PLCG2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSTTVNVDSLAEYEKSQIKRALELGTVMTVFSFRKSTPERRTVQVIMETRQVAWSKTADKIEGFLDIMEIKEIRPGKNSKDFERAKAVRQKEDCCFTILYGTQFVLSTLSLAADSKEDAVNWLSGLKILHQEAMNASTPTIIESWLRKQIYSVDQTRRNSISLRELKTILPLINFKVSSAKFLKDKFVEIGAHKDELSFEQFHLFYKKLMFEQQKSILDEFKKDSSVFILGNTDRPDASAVYLHDFQRFLIHEQQEHWAQDLNKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENSIWDEKYDAVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSPEAYIRCLRMGCRCIELDCWDGPDGKPVIYHGWTRTTKIKFDDVVQAIKDHAFVTSSFPVILSIEEHCSVEQQRHMAKAFKEVFGDLLLTKPTEASADQLPSPSQLREKIIIKHKKLGPRGDVDVNMEDKKDEHKQQGELYMWDSIDQKWTRHYCAIADAKLSFSDDIEQTMEEEVPQDIPPTELHFGEKWFHKKVEKRTSAEKLLQEYCMETGGKDGTFLVRESETFPNDYTLSFWRSGRVQHCRIRSTMEGGTLKYYLTDNLTFSSIYALIQHYRETHLRCAEFELRLTDPVPNPNPHESKPWYYDSLSRGEAEDMLMRIPRDGAFLIRKREGSDSYAITFRARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYYEKHSLYRKMRLRYPVTPELLERYNMERDINSLYDVSRMYVDPSEINPSMPQRTVKALYDYKAKRSDELSFCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVEDISTADFEELEKQIIEDNPLGSLCRGILDLNTYNVVKAPQGKNQKSFVFILEPKQQGDPPVEFATDRVEELFEWFQSIREITWKIDTKENNMKYWEKNQSIAIELSDLVVYCKPTSKTKDNLENPDFREIRSFVETKADSIIRQKPVDLLKYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTADKYMQMNHALFSLNGRTGYVLQPESMRTEKYDPMPPESQRKILMTLTVKVLGARHLPKLGRSIACPFVEVEICGAEYDNNKFKTTVVNDNGLSPIWAPTQEKVTFEIYDPNLAFLRFVVYEEDMFSDPNFLAHATYPIKAVKSGFRSVPLKNGYSEDIELASLLVFCEMRPVLESEEELYSSCRQLRRRQEELNNQLFLYDTHQNLRNANRDALVKEFSVNENQLQLYQEKCNKRLREKRVSNSKFYS", "length": 1265 }, "evidence": [ { "id": "MGI:97616", "url": "https://alliancegenome.org/gene/MGI:97616#orthology", "database": "AGR" }, { "id": "HGNC:9066", "url": "https://alliancegenome.org/gene/HGNC:9066#orthology", "database": "AGR" }, { "id": "FB:FBgn0003416", "url": "https://alliancegenome.org/gene/FB:FBgn0003416#orthology", "database": "AGR" }, { "id": "RGD:3348", "url": "https://alliancegenome.org/gene/RGD:3348#orthology", "database": "AGR" }, { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P19174-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "gene_name": "PLCG1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGAASPCANGCGPGAPSDAEVLHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQITWSRGADKIEGAIDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHCFVILYGMEFRLKTLSLQATSEDEVNMWIKGLTWLMEDTLQAPTPLQIERWLRKQFYSVDRNREDRISAKDLKNMLSQVNYRVPNMRFLRERLTDLEQRSGDITYGQFAQLYRSLMYSAQKTMDLPFLEASTLRAGERPELCRVSLPEFQQFLLDYQGELWAVDRLQVQEFMLSFLRDPLREIEEPYFFLDEFVTFLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMGCRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIAQQRNMAQYFKKVLGDTLLTKPVEISADGLPSPNQLKRKILIKHKKLAEGSAYEEVPTSMMYSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPKEVSSSTELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMRLSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYGALYEGRNPGFYVEANPMPTFKCAVKALFDYKAQREDELTFIKSAIIQNVEKQEGGWWRGDYGGKKQLWFPSNYVEEMVNPVALEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKNNRLFVFSISMASVAHWSLDVAADSQEELQDWVKKIREVAQTADARLTEGKIMERRKKIALELSELVVYCRPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRIYPKGQRLDSSNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFMTGRHCGYVLQPSTMRDEAFDPFDKSSLRGLEPCAISIEVLGARHLPKNGRGIVCPFVEIEVAGAEYDSTKQKTEFVVDNGLNPVWPAKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAVPLKNNYSEDLELASLLIKIDIFPAKENGDLSPFSGTSLRERGSDASGQLFHGRAREGSFESRYQQPFEDFRISQEHLADHFDSRERRAPRRTRVNGDNRL", "length": 1290 }, "evidence": [ { "id": "RGD:3347", "url": "https://alliancegenome.org/gene/RGD:3347#orthology", "database": "AGR" }, { "id": "MGI:97615", "url": "https://alliancegenome.org/gene/MGI:97615#orthology", "database": "AGR" }, { "id": "HGNC:9065", "url": "https://alliancegenome.org/gene/HGNC:9065#orthology", "database": "AGR" }, { "id": "FB:FBgn0003416", "url": "https://alliancegenome.org/gene/FB:FBgn0003416#orthology", "database": "AGR" }, { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" }, { "id": "Q9VXH3", "url": "https://omabrowser.org/oma/group/Q9VXH3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P24135-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2", "gene_name": "Plcg2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTTMVNVDTLPEYEKSQIKRALELGTVMTVFSARKSTPERRTVQMIMETRQVAWSKTADKIEGFLDIMEIKEIRPGKNSKDFERAKAVRHKADCCFTIFYGTQFVLSTLSLATDSKEDAVKWLSGLKILHQEAMNASTPTMIESWLRKQIYSVDQTRRNSISLRELKTILPLVNFKVSGIKFLKDKLVEIGAQKDELSFEQFHLFYKKLMFEQQKSILDEFKKDSSVFILGNTDRPDASAVYLQDFQRFLLHEQQELWAQDLNKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENSIWDEKYDAVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSTEAYIRCLRAGCRCIELDCWDGPDGKPIIYHGWTRTTKIKFDDVVQAIRDHAFVTSSFPVILSIEEHCSVEQQRHMAKVFKEVLGDLLLTKPTEASADQLPSPSQLREKIIIKHKKLGPRGDVDVNVEDKKDEHKTQGELYMWDSIDQKWTRHYCAIADAKLSFSDDIEQTVEEDPVQDTPPTELHFGEKWFHKKVESRTSAEKLLQEYCAETGAKDGTFLVRESETFPNDYTLSFWRSGRVQHCRIRSTMEGGVMKYYLTDNLTFNSIYALIQHYREAHLRCAEFELRLTDPVPNPNPHESKPWYYDRLSRGEAEDMLMRIPRDGAFLIRKREGTDSYAITFRARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYYEKHALYRKMRLRYPVTPELLERYNMERDINSLYDVSRMYVDPSEINPSMPQRTVKALYDYKAKRSDELTFCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVEDISAGDAEEMEKQIIEDNPLGSLCRGILDLNTYNVVKAPQGKNQKAFVFILEPKKQGDPPVEFATDRVEELFEWFQSIREITWKIDTKENNMKYWERNQSIAIELSDLVVYCKPTSKTKDHLENPDFREIRSFVETKADSIVRQKPVDLLRYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTPDKYMQMNHALFSLNGRTGYVLQPESMRSEKYDPMPPESQRKILMTLTVKVLGARHLPKLGRSIACPFVEVEICGAEYDSNKFKTTVVNDNGLSPVWAPTQEKVTFEIYDPNLAFLRFLVYEEDMFSDPNFLAHATYPIKGIKSGFRSVPLKNGYSEDIELASLLVFCEMRPVLESEEELYSSCRQLRRRQEELNNQLFLYDTHQNLRGANRDALVKEFNVNENQLRLYQEKCNRRLREKRVSNSRFYS", "length": 1265 }, "evidence": [ { "id": "MGI:97616", "url": "https://alliancegenome.org/gene/MGI:97616#orthology", "database": "AGR" }, { "id": "HGNC:9066", "url": "https://alliancegenome.org/gene/HGNC:9066#orthology", "database": "AGR" }, { "id": "FB:FBgn0003416", "url": "https://alliancegenome.org/gene/FB:FBgn0003416#orthology", "database": "AGR" }, { "id": "RGD:3348", "url": "https://alliancegenome.org/gene/RGD:3348#orthology", "database": "AGR" }, { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P25455-3", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase classes I and II", "gene_name": "Plc21C", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MMSAGGTYISTASVEVPQALQDGEKFIRWDDDSGTGTPVTMRVDAKGFFLYWVDQNNELDILDIATIRDVRTGQYAKRPKDNKLRQIVTLGPQDTLEEKTVTVCHGSDFVNMTFVNFCCTRRDIAQLWTDGLIKLAYSLAQLNGSAIMFLQKAHTKLCLQVDKSGRIPVKNIIKLFAQNKEDRKRVEKALDVTGLPSGKVDSISVSKFQFEDFYNLYKYLTQRSEVERLFDSIVGNSKRKCMSIAQLVEFLNKTQRDPRLNEILYPYANPARAKELIQQYEPNKFNAQKGQLSLDGFLRYLMGDDNPIMAPSKLDLCDDMDQPMSHYFINSSHNTYLTGHQLTGKSSVEIYRQCLLAGCRCVELDFWNGRTEEPVIVHGYTFVPEIFAKDVLEAIAESAFKTSEYPVILSFENHCNPRQQAKIANYCREIFGDMLLDKPLDSHPLEPNMDLPPPAMLRRKIIIKNKKKHHHHHHHHHHKKPAQVGTPAANNKLTTANSVDAKAAQQVGLSASHEDGGVTRSTANGDVATGTGTGSAAGTAGHAPPLQQIRQSSKDSTGSSDSDSSSEDESLPNTTPNLPSGNEPPPEKAQKETEAGAEISALVNYVQPIHFSSFENAEKKNRCYEMSSFDEKQATTLLKERPIEFVNYNKHQLSRVYPAGTRFDSSNFMPQLFWNAGCQLVALNFQTLDLAMQLNLGIFEYNARSGYLLKPEFMRRSDRRLDPFAESTVDGIIAGTVSITVLSGQFLTDKRANTFVEVDMYGLPADTVRKKFRTKTVRDNGMNPLYDEEPFVFKKVVLPELASIRIAAYEEGGKLIGHRVLPVIGLCPGYRHVNLRSEVGQPIALASLFLCVVVKDYVPDDLSNFAEALANPIKYQSELEKRDIQLSVLTDEAEALGSADEDLSKSFVFVQVGGQKKELRPVESLATSPKHRPSISAAAAMSVDVTVDRTDGGRGEDSISIVAPSIQHQHSLDQSVSTSIRQVESSQFDVDLVLAEPLEKILDHKSVKEKRLEMEKKLESLRKKHDKEKIKIAGQKSSPLEGKKPKFAITNKLVKRLSNKSLNCLSPHSEPGVEIPACPLDLGDSSEESAAADAGEDLAGGSSSLDGRTQESRLRSACREYTSQYRELQEKYHEAIYSAAEKVLKTSQTGQTKQLKASLDKVTGEVMHQLQEARRNEVKNLATVHRDRDELIRMKREVASSVVERGVAERVRLKQTFDRRTDELQKQHDSVRNALAEHRSKARQILDKEAESRSCVSSNGFLVLFHGPHHHGCTGSGSSALSGNNLTLNLDAGAAGSHSAISPAKSHNSIAAAAEMKT", "length": 1318 }, "evidence": [ { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P32383-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1", "gene_name": "PLC1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTESAIDDQRFNLTKELQRHSCRDQGKITQKDDALDFISYSSFQSSFNTDQKSANNGSTVRRSIRSIFRRAAELPRVHMGPLTYSHGINELVNKKLRKDCDLSTLCRVLQRGIRMIRMTRRRRKFYEFKLINNNGQIIWKDGSKYLELDSVKDIRIGDTASTYQEEVDPKRLRSDSKLWIAIIYKVSNKLKALHVVALNELDFNTFLSCICGLVKLRRELMESILLPDNSQFARIHWQITVSEKEEDEKKDTLSFADVKKLCDKFHIYVSTGQLLEFFQLADINHNGLLNYFEFEKFIKILKNRKEVNMIWSKFTKPPHSHLSFENFFQFLITEQHEQVDRQTAWSYFIKYREPTQLTMGQDGFTKFLKEQPYLVEVKEELYSKPLNHYFIASSHNTYLLGKQIAETPSVEGYIQVLQQGCRCVEIDIWDGENGPVVCHGFLTSAIPLKTVIRVIKKYAFITSPYPLIISLEINCNKDNQKLASLIMREVLAEQLYFVGTRTDKLPSPRELKHKILLKSKKTSEATRGLSVNEPFPSSFSSSYESANEQELRMKDDSTNSSSATNSSSMQRIKRIGLKKHADIINDVSNISGIHGIKFRNFSLPESKTIAHCFSLNERKVEYMIKDKHLKLSLDKHNRRYLMRVYPHVLRYKSSNFNPIPFWKAGVQMVATNWQTNDIGQQLNLAMFQILDHQPDGSFKSGYVLKPKKLLPVVTKAKMIPLIYEHFENGSDPVTVKIRILSTQLLPRLNDTSPSRNNTNSFVKVEFHTDDEPTMPISIDKGTRISATEASTKSSQGNGFNPIWDAEVSITLKDTDLTFIKFMVISEETQIASVCLKLNYLRMGYRHIPLFNMEGEQYIFCTLFIHTQIL", "length": 869 }, "evidence": [ { "id": "RGD:3347", "url": "https://alliancegenome.org/gene/RGD:3347#orthology", "database": "AGR" }, { "id": "MGI:97616", "url": "https://alliancegenome.org/gene/MGI:97616#orthology", "database": "AGR" }, { "id": "MGI:97615", "url": "https://alliancegenome.org/gene/MGI:97615#orthology", "database": "AGR" }, { "id": "HGNC:9066", "url": "https://alliancegenome.org/gene/HGNC:9066#orthology", "database": "AGR" }, { "id": "HGNC:9065", "url": "https://alliancegenome.org/gene/HGNC:9065#orthology", "database": "AGR" }, { "id": "FB:FBgn0003416", "url": "https://alliancegenome.org/gene/FB:FBgn0003416#orthology", "database": "AGR" }, { "id": "RGD:3348", "url": "https://alliancegenome.org/gene/RGD:3348#orthology", "database": "AGR" }, { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P51178-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1", "gene_name": "PLCD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDSGRDFLTLHGLQDDEDLQALLKGSQLLKVKSSSWRRERFYKLQEDCKTIWQESRKVMRTPESQLFSIEDIQEVRMGHRTEGLEKFARDVPEDRCFSIVFKDQRNTLDLIAPSPADAQHWVLGLHKIIHHSGSMDQRQKLQHWIHSCLRKADKNKDNKMSFKELQNFLKELNIQVDDSYARKIFRECDHSQTDSLEDEEIEAFYKMLTQRVEIDRTFAEAAGSGETLSVDQLVTFLQHQQREEAAGPALALSLIERYEPSETAKAQRQMTKDGFLMYLLSADGSAFSLAHRRVYQDMGQPLSHYLVSSSHNTYLLEDQLAGPSSTEAYIRALCKGCRCLELDCWDGPNQEPIIYHGYTFTSKILFCDVLRAIRDYAFKASPYPVILSLENHCTLEQQRVMARHLHAILGPMLLNRPLDGVTNSLPSPEQLKGKILLKGKKLGGLLPPGGEGGPEATVVSDEDEAAEMEDEAVRSRVQHKPKEDKLRLAQELSDMVIYCKSVHFGGFSSPGTPGQAFYEMASFSENRALRLLQESGNGFVRHNVGHLSRIYPAGWRTDSSNYSPVEMWNGGCQIVALNFQTPGPEMDVYQGRFQDNGACGYVLKPAFLRDPNGTFNPRALAQGPWWARKRLNIRVISGQQLPKVNKNKNSIVDPKVTVEIHGVSRDVASRQTAVITNNGFNPWWDTEFAFEVVVPDLALIRFLVEDYDASSKNDFIGQSTIPLNSLKQGYRHVHLMSKNGDQHPSATLFVKISLQD", "length": 756 }, "evidence": [ { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P51432-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3", "gene_name": "Plcb3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGARPGVHALQLEPPTVVETLRRGSKFIKWDEEASSRNLVTLRVDPNGFFLYWTGPNMEVDTLDISSIRDTRTGRYARLPKDPKIREVLGFGGPDTRLEEKLMTVVAGPDPVNTTFLNFMAVQDDTVKVWSEELFKLAMNILAQNASRNTFLRKAYTKLKLQVNQDGRIPVKNILKMFSADKKRVETALESCGLNFNRSESIRPDEFPLEIFERFLNKLCLRPDIDKILLEIGAKGKPYLTLEQLMDFINQKQRDPRLNEVLYPPLRSSQARLLIEKYETNKQFLERDQMSMEGFSRYLGGEENGILPLEALDLSMDMTQPLSAYFINSSHNTYLTAGQLAGPSSVEMYRQALLWGCRCVELDVWKGRPPEEEPFITHGFTMTTEVPLRDVLEAIAEAAFKTSPYPVILSFENHVDSAKQQAKMAEYCRSIFGDALLIDPLDKYPLSAGIPLPSPQDLMGRILVKNKKRHRPSTGVPDSSVRKRPLEQSNSALSESSAATEPSSPQLGSPSSDSCPGLSNGEEVGLEKTSLEPQKSLGEESLSREPNVPMPDRDREDEEEDEEEEETTDPKKPTTDEGTASSEVNATEEMSTLVNYVEPVKFKSFEAARKRNKCFEMSSFVETKAMEQLTKSPMEFVEYNKQQLSRIYPKGTRVDSSNYMPQLFWNVGCQLVALNFQTLDLPMQLNAGVFEYNGRSGYLLKPEFMRRPDKSFDPFTEVIVDGIVANALRVKVISGQFLSDKKVGIYVEVDMFGLPVDTRRKYRTRTSQGNSFNPVWDEEPFDFPKVVLPTLASLRIAAFEEGGKFVGHRILPVSAIRSGYHYVCLRNEANQPLCLPALLIYTEASDYIPDDHQDYAEALINPIKHVSLMDQRAKQLAALIGESEAQASTETYQETPCQQPGSQLPSNPTPNPLDASPRWPPGPTTSSTSSSLSSPGQRDDLIASILSEVTPTPLEELRSHKAMVKLRSRQDRDLRELHKKHQRKAVALTRRLLDGLAQARAEGKCRPSPSALGKATNSEDVKEEEEAKQYREFQNRQVQSLLELREAQADVETKRKLEHLRQAHQRLKEVVLDTHTTQFKRLKELNEREKKELQKILDRKRNNSISEAKTREKHKKEVELTEINRRHITESVNSIRRLEEAQKQRHERLVAGQQQVLQQLEEEEPKLLAQLTQECQEQRERLPQEIRRCLLGETAEGLGDGPLVACASNGHAPGSGGHLSSADSESQEENTQL", "length": 1234 }, "evidence": [ { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q00722-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2", "gene_name": "PLCB2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLLNPVLLPPKVKAYLSQGERFIKWDDETTVASPVILRVDPKGYYLYWTYQSKEMEFLDITSIRDTRFGKFAKMPKSQKLRDVFNMDFPDNSFLLKTLTVVSGPDMVDLTFHNFVSYKENVGKAWAEDVLALVKHPLTANASRSTFLDKILVKLKMQLNSEGKIPVKNFFQMFPADRKRVEAALSACHLPKGKNDAINPEDFPEPVYKSFLMSLCPRPEIDEIFTSYHAKAKPYMTKEHLTKFINQKQRDSRLNSLLFPPARPDQVQGLIDKYEPSGINAQRGQLSPEGMVWFLCGPENSVLAQDKLLLHHDMTQPLNHYFINSSHNTYLTAGQFSGLSSAEMYRQVLLSGCRCVELDCWKGKPPDEEPIITHGFTMTTDIFFKEAIEAIAESAFKTSPYPIILSFENHVDSPRQQAKMAEYCRTIFGDMLLTEPLEKFPLKPGVPLPSPEDLRGKILIKNKKNQFSGPTSSSKDTGGEAEGSSPPSAPAGEGTVWAGEEGTELEEEEVEEEEEEESGNLDEEEIKKMQSDEGTAGLEVTAYEEMSSLVNYIQPTKFVSFEFSAQKNRSYVISSFTELKAYDLLSKASVQFVDYNKRQMSRIYPKGTRMDSSNYMPQMFWNAGCQMVALNFQTMDLPMQQNMAVFEFNGQSGYLLKHEFMRRPDKQFNPFSVDRIDVVVATTLSITVISGQFLSERSVRTYVEVELFGLPGDPKRRYRTKLSPSTNSINPVWKEEPFVFEKILMPELASLRVAVMEEGNKFLGHRIIPINALNSGYHHLCLHSESNMPLTMPALFIFLEMKDYIPGAWADLTVALANPIKFFSAHDTKSVKLKEAMGGLPEKPFPLASPVASQVNGALAPTSNGSPAARAGAREEAMKEAAEPRTASLEELRELKGVVKLQRRHEKELRELERRGARRWEELLQRGAAQLAELGPPGVGGVGACKLGPGKGSRKKRSLPREESAGAAPGEGPEGVDGRVRELKDRLELELLRQGEEQYECVLKRKEQHVAEQISKMMELAREKQAAELKALKETSENDTKEMKKKLETKRLERIQGMTKVTTDKMAQERLKREINNSHIQEVVQVIKQMTENLERHQEKLEEKQAACLEQIREMEKQFQKEALAEYEARMKGLEAEVKESVRACLRTCFPSEAKDKPERACECPPELCEQDPLIAKADAQESRL", "length": 1185 }, "evidence": [ { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q01970-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3", "gene_name": "PLCB3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGAQPGVHALQLEPPTVVETLRRGSKFIKWDEETSSRNLVTLRVDPNGFFLYWTGPNMEVDTLDISSIRDTRTGRYARLPKDPKIREVLGFGGPDARLEEKLMTVVSGPDPVNTVFLNFMAVQDDTAKVWSEELFKLAMNILAQNASRNTFLRKAYTKLKLQVNQDGRIPVKNILKMFSADKKRVETALESCGLKFNRSESIRPDEFSLEIFERFLNKLCLRPDIDKILLEIGAKGKPYLTLEQLMDFINQKQRDPRLNEVLYPPLRPSQARLLIEKYEPNQQFLERDQMSMEGFSRYLGGEENGILPLEALDLSTDMTQPLSAYFINSSHNTYLTAGQLAGTSSVEMYRQALLWGCRCVELDVWKGRPPEEEPFITHGFTMTTEVPLRDVLEAIAETAFKTSPYPVILSFENHVDSAKQQAKMAEYCRSIFGDALLIEPLDKYPLAPGVPLPSPQDLMGRILVKNKKRHRPSAGGPDSAGRKRPLEQSNSALSESSAATEPSSPQLGSPSSDSCPGLSNGEEVGLEKPSLEPQKSLGDEGLNRGPYVLGPADREDEEEDEEEEEQTDPKKPTTDEGTASSEVNATEEMSTLVNYIEPVKFKSFEAARKRNKCFEMSSFVETKAMEQLTKSPMEFVEYNKQQLSRIYPKGTRVDSSNYMPQLFWNVGCQLVALNFQTLDVAMQLNAGVFEYNGRSGYLLKPEFMRRPDKSFDPFTEVIVDGIVANALRVKVISGQFLSDRKVGIYVEVDMFGLPVDTRRKYRTRTSQGNSFNPVWDEEPFDFPKVVLPTLASLRIAAFEEGGKFVGHRILPVSAIRSGYHYVCLRNEANQPLCLPALLIYTEASDYIPDDHQDYAEALINPIKHVSLMDQRARQLAALIGESEAQAGQETCQDTQSQQLGSQPSSNPTPSPLDASPRRPPGPTTSPASTSLSSPGQRDDLIASILSEVAPTPLDELRGHKALVKLRSRQERDLRELRKKHQRKAVTLTRRLLDGLAQAQAEGRCRLRPGALGGAADVEDTKEGEDEAKRYQEFQNRQVQSLLELREAQVDAEAQRRLEHLRQALQRLREVVLDANTTQFKRLKEMNEREKKELQKILDRKRHNSISEAKMRDKHKKEAELTEINRRHITESVNSIRRLEEAQKQRHDRLVAGQQQVLQQLAEEEPKLLAQLAQECQEQRARLPQEIRRSLLGEMPEGLGDGPLVACASNGHAPGSSGHLSGADSESQEENTQL", "length": 1234 }, "evidence": [ { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q15111-1", "protein_name": "Inactive phospholipase C-like protein 1", "gene_name": "PLCL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEGAAGREDPAPPDAAGGEDDPRVGPDAAGDCVTAASGGRMRDRRSGVALPGAAGTPADSEAGLLEAARATPRRSSIIKDPSNQKCGGRKKTVSFSSMPSEKKISSANDCISFMQAGCELKKVRPNSRIYNRFFTLDTDLQALRWEPSKKDLEKAKLDISAIKEIRLGKNTETFRNNGLADQICEDCAFSILHGENYESLDLVANSADVANIWVSGLRYLVSRSKQPLDFMEGNQNTPRFMWLKTVFEAADVDGNGIMLEDTSVELIKQLNPTLKEAKIRLKFKEIQKSKEKLTTRVTEEEFCEAFCELCTRPEVYFLLVQISKNKEYLDANDLMLFLEAEQGVTHITEDICLDIIRRYELSEEGRQKGFLAIDGFTQYLLSSECDIFDPEQKKVAQDMTQPLSHYYINASHNTYLIEDQFRGPADINGYIRALKMGCRSVELDVSDGSDNEPILCNRNNMTTHVSFRSVIEVINKFAFVASEYPLILCLGNHCSLPQQKVMAQQMKKVFGNKLYTEAPLPSESYLPSPEKLKRMIIVKGKKLPSDPDVLEGEVTDEDEEAEMSRRMSVDYNGEQKQIRLCRELSDLVSICKSVQYRDFELSMKSQNYWEMCSFSETEASRIANEYPEDFVNYNKKFLSRIYPSAMRIDSSNLNPQDFWNCGCQIVAMNFQTPGPMMDLHTGWFLQNGGCGYVLRPSIMRDEVSYFSANTKGILPGVSPLALHIKIISGQNFPKPKGACAKGDVIDPYVCIEIHGIPADCSEQRTKTVQQNSDNPIFDETFEFQVNLPELAMIRFVVLDDDYIGDEFIGQYTIPFECLQPGYRHVPLRSFVGDIMEHVTLFVHIAITNRSGGGKAQKRSLSVRMGKKVREYTMLRNIGLKTIDDIFKIAVHPLREAIDMRENMQNAIVSIKELCGLPPIASLKQCLLTLSSRLITSDNTPSVSLVMKDSFPYLEPLGAIPDVQKKMLTAYDLMIQESRFLIEMADTVQEKIVQCQKAGMEFHEELHNLGAKEGLKGRKLNKATESFAWNITVLKGQGDLLKNAKNEAIENMKQIQLACLSCGLSKAPSSSAEAKSKRSLEAIEEKESSEENGKL", "length": 1095 }, "evidence": [ { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q15147-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4", "gene_name": "PLCB4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKPYEFNWQKEVPSFLQEGAVFDRYEEESFVFEPNCLFKVDEFGFFLTWRSEGKEGQVLECSLINSIRSGAIPKDPKILAALEAVGKSENDLEGRIVCVCSGTDLVNISFTYMVAENPEVTKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFMTNTNGKIPVRSITRTFASGKTEKVIFQALKELGLPSGKNDEIEPTAFSYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMYEPDEDLKKKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQALESHPLEPGRALPSPNDLKRKILIKNKRLKPEVEKKQLEALRSMMEAGESASPANILEDDNEEEIESADQEEEAHPEFKFGNELSADDLGHKEAVANSVKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPSDTSKNDKKGKANTAKANVTPQSSSELRPTTTAALASGVEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKEHSTMQKLHCTQVDKIVAQYDKEKSTHEKILEKAMKKKGGSNCLEMKKETEIKIQTLTSDHKSKVKEIVAQHTKEWSEMINTHSAEEQEIRDLHLSQQCELLKKLLINAHEQQTQQLKLSHDRESKEMRAHQAKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMKQSKEMDQLKKVQLEHLEFLEKQNEQAKEMQQMVKLEAEMDRRPATVV", "length": 1175 }, "evidence": [ { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q1LWV7-1", "protein_name": "MTOR-associated protein MEAK7", "gene_name": "meak7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGNGDSVVAQKRLARFRPDERPAVEGTFDRLHGARSSASAGKTSKGLSLDMLQLTMGKMASESMIKRVFQGLHSIDPGVPLHPGDGVSREQLLIFLADVLRGTAEERAPLVLAMAEGAKATVTTTEQIRGFMEDLVYAAVQTLAHKGHLRAWHPERMGDGAQGVKLLAEQLTSELKPSDQNSCDIACLEDWLFRIPMMAMFLELLIGEGLGVVLPSRPPPTLLPPCQFAPWTDLRCVLSLPLLMFLSPLLPEGHSAPWRMLFSTKMHGESFTRLLGSCKSRGPTVLLVKDTKGYIFGGFSSQSWEVKPQFQGDSRCFLFSVFPYMRVFTCTGYNDHYMYLNQGQQTMPNGLGMGGQHGYFGLWLDYDFGHGHSRARPRCTTYGSPQLSADEDFKLDTLEVWGVGKLPEEQEEDEKKKSILDADLEVQAMMEMTGKTLHSQGLREPEEDED", "length": 450 }, "evidence": [ { "id": "MGI:97616", "url": "https://alliancegenome.org/gene/MGI:97616#orthology", "database": "AGR" }, { "id": "HGNC:9066", "url": "https://alliancegenome.org/gene/HGNC:9066#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q3USB7-1", "protein_name": "Inactive phospholipase C-like protein 1", "gene_name": "Plcl1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEGAASREAPAPLDVAGGEDDPRAGADAASGDAPPPALGGRMRDRRSGVALPGAAGVPADSEAGLLEAARATPRRSSIIKDPSNQKCGGRKKTVSFSSMPSEKKISSAHDCISFMQAGCELKKVRPNSRIYNRFFTLDTDLQALRWEPSKKDLEKAKLDISAIKEIRLGKNTETFRNNGLADQICEDCAFSILHGENYESLDLVANSADVANIWVSGLRYLVSRSKQPLDFIEGNQNTPRFMWLKTVFEAADVDGNGIMLEDTSVELIKQLNPTLKESKIRLKFKEIQKSKEKLTTRVTEEEFCEAFCELCTRPEVYFLLVQISKNKEYLDANDLMLFLEAEQGVTHITEDMCLDIIRRYELSEDGRQKGFLAIDGFTQYLLSPECDIFDPEQKKVAQDMTQPLSHYYINASHNTYLIEDQFRGPADINGYVRALKMGCRSIELDVSDGPDNEPILCNRNNMAMHLSFRSVLEVINKFAFVASEYPLILCLGNHCSLPQQKVMAQQMKKVFGEKLYTEAPLSSESYLPSPEKLKNMIIVKGKKLPSESDLLEGEVTDEDEEAEMSRRMSGDYNGEQKHIWLCRELSDLVSICKSVQHRDFELSMKTQNYWEMCSFSETEASRIANEYPEDFVNYNKKFLSRVYPSAMRIDSSNLNPQDFWNCGCQIVAMNFQTPGPMMDLHTGWFLQNGGCGYVLRPSIMRDEVSYFSANTKGIVPGVSPLVLHIKIISGQNFPKPKGACAKGDVIDPYVCVEIHGIPADCCEQRTKTVQQNSDNPIFDETFEFQVNLPELTMVRFVILDDDYIGDEFIGQYTIPFECLQPGYRHVPLRSFVGDIMEHVTLFVHIAITNRSGGGKPQKRSLSVRMGKKVREYTMLRNIGLKTIDDIFKIAVHPLREAIDMRENMQNAIVSVKELCGLPPIASLKQCLLTLSSRLITSDSTPSVSLVMKDCFPYLEPLGAIPDVQKRMLAAYDLMIQESRVLIEMADTVQEKIVQCQKAGMEFHEELHNLGAKEGLKGRKLNKAIESFAWNITVLKGQGDLLKNAKNEAVENIKQIQLACLSCGLSKGPGGGSEAKGKRSLEAIEEKESSEENGKL", "length": 1096 }, "evidence": [ { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q4KWH5-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1", "gene_name": "Plch1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADLEVYKNLSPEKVERCMSVMQSGTQMIKLKRGTKGLVRLFYLDEHRTRLRWRPSRKSEKAKILIDSIYKVTEGRQSEIFHRQAEGNFDPSCCFTIYHGNHMESLDLITSNPEEARTWITGLKYLMAGISDEDSLAKRQRTHDQWVKQTFEEADKNGDGLLNIEEIHQLMHKLNVNLPRRKVRQMFQEADTDENQGTLTFEEFCVFYKMMSLRRDLYLLLLSYSDKKDHLTVEELAQFLKVEQKMSNVTLDYCLDIIMKFEVSEENKVKNVLGIEGFTNFMRSPACDVFNPLHHEVYQDMDQPLCNYYIASSHNTYLTGDQLLSQSKVDMYARVLQEGCRCVEVDCWDGPDGEPVVHHGYTLTSKILFRDVVETINKHAFVKNEFPVILSIENHCSIQQQRKIAQYLKGILQDKLDLSSVDTGECRQLPSPQSLKGKILVKGKKLPYHLGDDAEEGEVSDEDSADEIEDECKFKLHYSNGTTEHQVESFIRKKLESLLKESQIRDKEDPDSFTVRALLKATHEGLNAHLKQNLDVKESGKKSHGRSLMANFGKHKQKATKSRSKSYSTDDEDDSLQNPGKEGGQLYRLGRRRRTMKLCRELSDLVVYTNSVAAQDIVDDGTTGNVLSFSETRAHQVVQQKSEQFMIYNQKQLTRIYPSAYRIDSSNFNPLPYWNAGCQLVALNYQSEGRMMQINRAKFKANGNCGYILKPQQMCKGTFNPFSGDPLPANPKKQLILKVISGQQLPKPPDSMFGDRGEIIDPFVEVEIIGLPVDCCKDQTRVVDDNGFNPVWEETLTFTVHMPEIALVRFLVWDHDPIGRDFVGQRTVTFSSLVPGYRHVYLEGLTEASIFVHITINEIFGKWSPLILNPSYTILHFLGATKNRQLQGLKGLFNKNPRHASSENNSHYVRKRSIGDRILRRTASAPAKGRKKSKVGFQEMVEIKDSVSEASRDQDGVLRRTTRSLQVRPVSMPVDKSLLGALSLPISEAAKDTDGKENCLAGDKDDRRKGAATRKDPHFSNFNKKLSSSSSALLHKDANQGPTASVSNPEQCGGRGAKSERIKPNMTNDCQENHNPPKFLSPRKHLALDPATKGLQERLHGMKTNEKEHAEGFLGEKSMLSGSVLSQSSLEVENLEGSRAKGRAATSFSLSDVSALCSDIPDLHSTAILQDTEISNLIDDVTLTNENQSGSSISALIGQFEESNHPANVTVVSHLSTSGASGSAPFQTPFKHGLSQGNQKASFLCSSPELNKLSSVETTKLANNAVPCGVIGSPISTPKPGDDPSDKAKTRVIEGNLPGFPDASPGQFPKSPTHGEDHSQVMNSPALSTELAIEDIIADPALSINSAESSLVEIDGESENLSLTTCDYREEAPSQLVSPLKLQQSQEMVEHIQRGLRNGYCKETLLPSEIFNNIPGVKNHSISHLTYQGAGFVYNHFSSSDAKTNQICEPQQPRAPDMHAPTPTPSTHAPLAALKLPSPCKSKSLGDLTSEDIACNFESKYQCISRSFVTNGIRDKSVTMKTKSLEPLDALTEQLRKLVSFDQEDSCQVLYSKQDVNQCPRALVRKLSSRSQSRVRNIASRAKEKQEAGKQKAMAQSTRGGVVLRSKPPAPALAVNRHSTGSYIASYLRNMKAGGLEGRGIPEGACTALRYGYMDQFCSDNSVLQTEPSSEDKPEIYFLLRL", "length": 1682 }, "evidence": [ { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q4KWH8-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1", "gene_name": "PLCH1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADLEVYKNLSPEKVERCMSVMQSGTQMIKLKRGTKGLVRLFYLDEHRTRLRWRPSRKSEKAKILIDSIYKVTEGRQSEIFHRQAEGNFDPSCCFTIYHGNHMESLDLITSNPEEARTWITGLKYLMAGISDEDSLAKRQRTHDQWVKQTFEEADKNGDGLLNIEEIHQLMHKLNVNLPRRKVRQMFQEADTDENQGTLTFEEFCVFYKMMSLRRDLYLLLLSYSDKKDHLTVEELAQFLKVEQKMNNVTTDYCLDIIKKFEVSEENKVKNVLGIEGFTNFMRSPACDIFNPLHHEVYQDMDQPLCNYYIASSHNTYLTGDQLLSQSKVDMYARVLQEGCRCVEVDCWDGPDGEPVVHHGYTLTSKILFRDVVETINKHAFVKNEFPVILSIENHCSIQQQRKIAQYLKGIFGDKLDLSSVDTGECKQLPSPQSLKGKILVKGKKLPYHLGDDAEEGEVSDEDSADEIEDECKFKLHYSNGTTEHQVESFIRKKLESLLKESQIRDKEDPDSFTVRALLKATHEGLNAHLKQSPDVKESGKKSHGRSLMTNFGKHKKTTKSRSKSYSTDDEEDTQQSTGKEGGQLYRLGRRRKTMKLCRELSDLVVYTNSVAAQDIVDDGTTGNVLSFSETRAHQVVQQKSEQFMIYNQKQLTRIYPSAYRIDSSNFNPLPYWNAGCQLVALNYQSEGRMMQLNRAKFKANGNCGYVLKPQQMCKGTFNPFSGDPLPANPKKQLILKVISGQQLPKPPDSMFGDRGEIIDPFVEVEIIGLPVDCCKDQTRVVDDNGFNPVWEETLTFTVHMPEIALVRFLVWDHDPIGRDFVGQRTVTFSSLVPGYRHVYLEGLTEASIFVHITINEIYGKWSPLILNPSYTILHFLGATKNRQLQGLKGLFNKNPRHSSSENNSHYVRKRSIGDRILRRTASAPAKGRKKSKMGFQEMVEIKDSVSEATRDQDGVLRRTTRSLQARPVSMPVDRNLLGALSLPVSETAKDIEGKENSLAEDKDGRRKGKASIKDPHFLNFNKKLSSSSSALLHKDTSQGDTIVSTAHMSVTGEQLGMSSPRGGRTTSNATSNCQENPCPSKSLSPKQHLAPDPVVNPTQDLHGVKIKEKGNPEDFVEGKSILSGSVLSHSNLEIKNLEGNRGKGRAATSFSLSDVSMLCSDIPDLHSTAILQESVISHLIDNVTLTNENEPGSSISALIGQFDETNNQALTVVSHLHNTSVMSGHCPLPSLGLKMPIKHGFCKGKSKSSFLCSSPELIALSSSETTKHATNTVYETTCTPISKTKPDDDLSSKAKTAALESNLPGSPNTSRGWLPKSPTKGEDWETLKSCSPASSPDLTLEDVIADPTLCFNSGESSLVEIDGESENLSLTTCEYRREGTSQLASPLKLKYNQGVVEHFQRGLRNGYCKETLRPSVPEIFNNIQDVKTQSISYLAYQGAGFVHNHFSDSDAKMFQTCVPQQSSAQDMHVPVPKQLAHLPLPALKLPSPCKSKSLGDLTSEDIACNFESKYQCISKSFVTTGIRDKKGVTVKTKSLEPIDALTEQLRKLVSFDQEDNCQVLYSKQDANQLPRALVRKLSSRSQSRVRNIASRAKEKQEANKQKVPNPSNGAGVVLRNKPSAPTPAVNRHSTGSYIAGYLKNTKGGGLEGRGIPEGACTALHYGHVDQFCSDNSVLQTEPSSDDKPEIYFLLRL", "length": 1693 }, "evidence": [ { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5FX52-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1", "gene_name": "Plcz1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESHYELAEARWFMSKIQDYFRGGKISAGITHKLLEKLDFPCHFAHVKRIFKENDRHNQGRITTEDFRTIYRCIVHREEIVEIFNTYTENRKILPEDSLIEFLTQEQYEMEMDESSSVEIIQKYEPIAEVKNERQMSIEGFARYMFSSECLLFKETCNTVYQDMNKPLNDYYISSSHNTYLISDQILGPSDIWGYISALVKGCRCLEIDCWDGAQNEPIVYHGYTLTSKLLFKTVIQAINKYAFVTSDYPVVLSLENHCSPGQQEVMTDILQSTFGDFLLSDILDEFPDSLPSPEALKFKILVKNKKVGTLSETRERLGTDKRGIALDLEEEIYENEDEDSGKEPETWDDFLSRVKEEQEADPSTLSGIADAKKKIRKLRVALALSDLVIYTKAEKFRNFQYSRVYQQFNETTSMGESRARKLSKLRAHEFIFHTAAFITRVYPKFTRADSSNFNPQEFWNVGCQMVALNFQTPGLPMDLQNGKFLDNGGSGYVLKPDFLRDTTLGFNPNEPEGDGHPVTLTIRLISGIQLPVNVPSNTSDIIVIIEVYGVPNDHMKQQSRAVKNNAFSPRWNETFTFLIQVPELALIRFVVETQGFLSGNELLGQYTLPVLCMNKGYRRVPLFSKSGANLEPSSLFIYVWYYRE", "length": 645 }, "evidence": [ { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q62077-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "gene_name": "Plcg1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGVATPCANGCGPGAPSEAEVLHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQITWSRGADKIEGSIDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHCFVILYGMEFRLKTLSLQATSEDEVNMWIKGLTWLMEDTLQAATPLQIERWLRKQFYSVDRNREDRISAKDLKNMLSQVNYRVPNMRFLRERLTDLEQRSGDITYGQFAQLYRSLMYSAQKTMDLPFLETNALRTGERPEHCQVSLSEFQQFLLEYQGELWAVDRLQVQEFMLSFLRDPLREIEEPYFFLDELVTFLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMGCRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIAQQRNMAQHFRKVLGDTLLTKPVDIAADGLPSPNQLRRKILIKHKKLAEGSAYEEVPTSVMYSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPKEASSSTELHSSEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMRLSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYGALYEGRNPGFYVEANPMPTFKCAVKALFDYKAQREDELTFTKSAIIQNVEKQDGGWWRGDYGGKKQLWFPSNYVEEMINPAVLEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKNNRLFVFSISMPSVAQWSLDVAADSQEELQDWVKKIREVAQTADARLTEGKMMERRKKIALELSELVVYCRPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRIYPKGQRLDSSNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFMAGGHCGYVLQPSTMRDEAFDPFDKSSLRGLEPCVICIEVLGARHLPKNGRGIVCPFVEIEVAGAEYDSTKQKTEFVVDNGLNPVWPAKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAVPLKNNYSEDLELASLLIKIDIFPAKENGDLSPFSGISLRERASDASSQLFHVRAREGSFEARYQQPFEDFRISQEHLADHFDSRERSTSDGPSSATNLIEDPLHDKLWKCSL", "length": 1302 }, "evidence": [ { "id": "RGD:3347", "url": "https://alliancegenome.org/gene/RGD:3347#orthology", "database": "AGR" }, { "id": "MGI:97615", "url": "https://alliancegenome.org/gene/MGI:97615#orthology", "database": "AGR" }, { "id": "HGNC:9065", "url": "https://alliancegenome.org/gene/HGNC:9065#orthology", "database": "AGR" }, { "id": "FB:FBgn0003416", "url": "https://alliancegenome.org/gene/FB:FBgn0003416#orthology", "database": "AGR" }, { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" }, { "id": "Q9VXH3", "url": "https://omabrowser.org/oma/group/Q9VXH3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q62688-1", "protein_name": "Inactive phospholipase C-like protein 1", "gene_name": "Plcl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEGAASREAPAPLDVAGGEDDPRAGADAASGDAAPEASGGRMRDRRSGVALPGNAGVPADSEAGLLEAARATPRRTSIIKDPSNQKCGGRKKTVSFSSMPSEKKISSAHDCISFMQAGCELKKVRPNSRIYNRFFTLDTDLQALRWEPSKKDLEKAKLDISAIKEIRLGKNTETFRNNGLADQICEDCAFSILHGENYESLDLVANSADVANIWVSGLRYLVSRSKQPLDFMEGNQNTPRFMWLKTVFEAADVDGNGIMLEDTSVELIKQLNPTLKESKIRLKFKEIQKSKEKLTTRVTEEEFCEAFCELCTRPEVYFLLVQISKNKEYLDANDLMLFLEVEQGVTHVTEDMCLDIIRRYELSEDGRQKGFLAIDGFTQYLLSPECDIFDPEQKKVAQDMTQPLSHYYINASHNTYLIEDQFRGPADINGYVRALKMGCRSIELDVSDGPDNEPILCNRNNMAMLLSFRSVLEVINKFAFVASEYPLILCLGNHCSLPQQRVMVQQMKKVFGNKLYTEAPLSSESYLPSPEKLKHMIIVKGKKLPSESDLLEGEVTDEDEEAEMSRRVSGDYNGEQKHIWLCRELSDLVSICKSVQYRDFELSMKTQNYWEICSFSETLASRIANEYPEDFVNYNKKFLSRVYPSAMRIDSSNLNPQDFWNCGCQIVAMNFQTPGPMMDLHTGWFLQNGGCGYVLRPSIMRDEVSYFSANTKGIVPGVSPLLLHIKIISGQNFPKPKGACAKGDVIDPYVCVEIHGIPADCSEQRTKTVQQNSDNPIFDETFEFQVNLPELTMVRFVILDDDYIGDEFIGQYTIPFECLQPGYRHVPLRSFVGDIMEHVTLFVHIAITNRSGGGKAQKRSLSVRMGKKVREYTMLRNIGLKTIDDIFKIAVHPLREAIDMRENMQNAIVSVKELCGLPPIASLKQCLLTLSSRLITSDSTPSVSLVMKDCFPYLEPLGTIPDVQKRMLAAYDLMIQESRVLIEMADTVQEKIVQCQKAGMEFHEELHNLGAKEGLKGRKLNKAIESFAWNITVLKGQGDLLKNAKNEAVENIKQIQLACLSCGLSKGPGSAAEAKGKRSLEAIEEKESSEENGKL", "length": 1096 }, "evidence": [ { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q62711-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4", "gene_name": "Plcd4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASQIQKLLTTNQDLLLMQKGTMMRKVRTKSWKKLRYFRLQDDGMTVWHGRHLESISKPTFSISDVERIRKGQDSELLRYLVEEFPLEQGFTIVFNGRRPNLDLVANSVEEAQTWMRGLQLLVDLVARMNYQEQLDQMLREWFQQADRNQDSRMSFREAQRLLLLMNVEMDEEYAFSLFQEADVSQSNTLDSEEFVQFYKALTKRTEIEELFENFSSDKQKLTLLEFVDFLREEQKESDHSSDLALKLIDRYEPSENGRLLRVLSKDGFLSYLCSADGNIFNPDCLPIYQDMTQPLSHYYINSSHNTYLLGDQFCGQSSVEGYIRALKRGCRCVEVDTWDGPDGEPVVYHGRTLTSRILFKDVLATLAQYAFQSSDYPLILSLDNHCTWEQQKTMAHHLIAILGEQLLSTTLEEQLIDIMPSPEQLRGKILVKGKKLRTIEVVESDKEEEELEKDEGSDLDPASAELDMQSQPESQEQASGNKSKNKKKFLLQSSTTILCPDLSALVVYLRTAPFCSFTHSKENYHIYDISSFSESKAKNLIREAGNEFVQHNARQLCRVYPSGLRTDSSNYNPQEHWNVGCQMVAMNMQTAGSAMDICDGLFRQNGGSGYVLKPEFLRDTQSSFNPMKPVSLYKAQILVVQVISGQRLPKVDKTKETTVVDPLVRVELYGVPEDTKQQETSYVENNGINPYWGETFYFQIQVPELAMLRFVVKDYSRTSRNNFIGQYTLPWTCMKHGYRHVSLLSKDGTSLHPASIFVYTCMQEDLDMDEP", "length": 772 }, "evidence": [ { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q86YW0-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1", "gene_name": "PLCZ1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEMRWFLSKIQDDFRGGKINLEKTQRLLEKLDIRCSYIHVKQIFKDNDRLKQGRITIEEFRAIYRIITHREEIIEIFNTYSENRKILLASNLAQFLTQEQYAAEMSKAIAFEIIQKYEPIEEVRKAHQMSLEGFTRYMDSRECLLFKNECRKVYQDMTHPLNDYFISSSHNTYLVSDQLLGPSDLWGYVSALVKGCRCLEIDCWDGAQNEPVVYHGYTLTSKLLFKTVIQAIHKYAFMTSDYPVVLSLENHCSTAQQEVMADNLQATFGESLLSDMLDDFPDTLPSPEALKFKILVKNKKIGTLKETHERKGSDKRGDNQDKETGVKKLPGVMLFKKKKTRKLKIALALSDLVIYTKAEKFKSFQHSRLYQQFNENNSIGETQARKLSKLRVHEFIFHTRKFITRIYPKATRADSSNFNPQEFWNIGCQMVALNFQTPGLPMDLQNGKFLDNGGSGYILKPHFLRESKSYFNPSNIKEGMPITLTIRLISGIQLPLTHSSSNKGDSLVIIEVFGVPNDQMKQQTRVIKKNAFSPRWNETFTFIIHVPELALIRFVVEGQGLIAGNEFLGQYTLPLLCMNKGYRRIPLFSRMGESLEPASLFVYVWYVR", "length": 608 }, "evidence": [ { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CIH5-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2", "gene_name": "Plcg2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTTMVNVDTLPEYEKSQIKRALELGTVMTVFNARKSTPERRTVQMIMETRQVAWSKTADKIEGFLDIMEIKEIRPGKNSKDFERAKAVRHKAECCFTILYGTQFVLSTLSLATDSKEDAVKWLSGLKILHQEAMSASTPTMIESWLRKQIYSVDQTRRNSISLRELKTILPLVNFKVSGIKFLKDKLVEIGAQKDELSFEQFHLFYKKLMFDQQKSILDEFKKDSSVFILGNTDRPDASAVYLQDFQRFLLHEQQELWAQDLNKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENSIWDEKYDAVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSTEAYIRCLRAGCRCIELDCWDGPDGKPIIYHGWTRTTKIKFDDVVQAIRDHAFVTSSFPVILSIEEHCSVEQQRHMAKVFKEVLGDMLLTKPTEASADQLPSPSQLREKIIIKHKKLGPKGDVDVNVEDKKDEHKPQGELYMWDSIDQKWTRHYCAIADAKLSFGDDIEQAVEEEPVQDTPPTELHFGEKWFHKKVESRTSAEKLLQEYCAETGAKDGTFLVRESETFPNDYTLSFWRSGRVQHCRIRSTMENGVMKYYLTDNLTFNSIYALIQHYREAHLRCAEFELRLTDPVPNPNPHESKPWYYDSLSRGEAEDMLMRIPRDGAFLIRKREGTNSYAITFRARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYYEKHALYRKMRLRYPVTPELLERYNMERDINSLYDVSRMYVDPSEINPSMPQRTVKALYDYKAKRSDELTFCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVEDISAGDAEEMEKQIIEDNPLGSLCKGILDLNTYNVVKAPQGKNQKAFVFILEPKKQGDPPVEFATDRVEELFEWFQSIREITWKMDTKENNMKYWERNQSIAIELSDLVVYCKPTSKTKDHLENPDFREIRSFVETKADSIVRQKPVDLLRYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTPDKYMQMNHALFSLNGRTGYVLQPESMRSEKYDPMPLESQRKILMTLTVKVLGARHLPKLGRSIACPFVEVEICGAEYDSNKFKTTVVNDNGLSPVWAPTQEKVTFEIYDPNLAFLRFVVYEEDMFSDPNFLAHATYPIKGIKSGFRSVPLKNGYSEDIELASLLVFCEMRPVLESEEELYSSCRQLRRRQEELNNQLFLYDTHQNLRGANRDALVKEFNVNENQLQLYQEKCNRRLREKRVSNSRFYS", "length": 1265 }, "evidence": [ { "id": "MGI:97616", "url": "https://alliancegenome.org/gene/MGI:97616#orthology", "database": "AGR" }, { "id": "HGNC:9066", "url": "https://alliancegenome.org/gene/HGNC:9066#orthology", "database": "AGR" }, { "id": "FB:FBgn0003416", "url": "https://alliancegenome.org/gene/FB:FBgn0003416#orthology", "database": "AGR" }, { "id": "RGD:3348", "url": "https://alliancegenome.org/gene/RGD:3348#orthology", "database": "AGR" }, { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8K2J0-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3", "gene_name": "Plcd3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLCGGWKRSRRSPEESRVSAQVAAPLAFPPSPASSDSSTKRPGLRALKKMGLTEDEDVQAMLRGSRLLKIRSRTWHKERLYRLQEDGLSVWFQRRIPRAASKHIFFVQHIEAVREGHQSEGLRRFGGAFAPACCLTIAFKGRRKNLDLAAPTAEEAQRWVRGLAKLRARLDAMSQRERLDHWIHSYLHRADSDQDSKMSFKEIKSLLRMVNVDMNDMYAYRLFKECDHSNNERLEGAEIEAFLRRLLKRPELEEIFRRYSGEDRVLSASELLEFLEDQGEDGATLACAQQLIQTYELNETAKQHELMTLDGFMMYLLSPEGAALNVAHTCVFQDMGQPLAHYFISSSHNTYLTDSQIGGTSSTEAYIRAFAQGCRCVELDCWEGPGGEPVIYHGHTLTSKILFRDVIQAVRDHAFTSSPYPVILSLENHCGLEQQAVMARHLRSILGDMLVTQALDSQNPEELPSPEQLKGRILVKGKKLPAARSEDGRILSDREEEEEEEEEAEEALEAAEQRSRAKQISPELSALAVYCCATRLRTLDPSPGPPQSCTVGSLSERKARKFTREAGTSFVRHNTQQLTRVYPLGLRMNSANYNPQEMWNSGCQLVALNFQTPGYEMDLNTGRFLINGQCGYVLKPAYLRQLNTTFDPECPGPPRTTLAIQVLTAQQLPKLNAEKPSSIVDPLVRVEIHGVPEDCAQKETDYVLNNGFNPCWEQTLQFRLRAPELVLVRFVVEDYDTTSPNDFVGQSTLPLSSLKQGYRHIHLLSKDGASLAPATLFVHIRIQNS", "length": 785 }, "evidence": [ { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8K394-1", "protein_name": "Inactive phospholipase C-like protein 2", "gene_name": "Plcl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAECGRGAAGGALPTSPSPALGAKGALKAGAGEGGGGGGGGRLGHGRARYDSGGVSNGDCSLGVSGDEARTSPGRGPLGVALARTPSPAAGPVPRDSKPGGLPRRSSIIKDGTKQKRERKKTVSFSSMPTEKKISSASDCINSMVEGSELKKVRSNSRIYHRYFLLDADMQSLRWEPSKKDSEKAKIDIKSIKEVRTGKNTDIFRSNGISEQISEDCAFSVIYGENYESLDLVANSADVANIWVTGLRYLISYGKHTLDMLESSQDNMRTSWISQMFSEIDVDGLGHITLCHAVQCIRNLNPGLKTSKIELKFKELHKSKDKAGTEITKEEFIEVFHELCTRPEIYFLLVQFSSNKEFLDTKDLMMFLEAEQGVAHINEEISLEIIHKYEPSKEGQEKGWLSIDGFTNYLMSPDCYIFDPEHKKVCQDMKQPLSHYFINSSHNTYLIEDQFRGPSDITGYIRALKMGCRSVELDVWDGPDNEPVIYTGHTMTSQIVFRSVIDIINKYAFFASEYPLILCLENHCSIKQQKVMVQHMKKILGDKLYTTSPNMEESYLPSPDVLKGKILIKAKKLSSNCSGVEGDVTDEDEGAEMSQRMGKENVEQPNHVPVKRFQLCKELSELVSICKSVQFKEFQVSFQVQKYWEVCSFNEVLASKYANENPGDFVNYNKRFLARVFPSPMRIDSSNMNPQDFWKCGCQIVAMNFQTPGLMMDLNVGWFRQNGNCGYVLRPAIMREEVSFFSANTKDSVPGVSPQLLHIKIISGQNFPKPKGSGAKGDVVDPYVYVEIHGIPADCAEQRTKTVNQNGDAPIFDESFEFQINLPELAMVRFVVLDDDYIGDEFIGQYTIPFECLQTGYRHVPLQSLTGEVLAHASLFVHVAITNRRGGGKPHKRGLSVRKGKKSREYASLRTLWIKTVDEVFKNAQPPIRDATDLRENMQNAVVSFKELCGLSSVANLMQCMLAVSPRFLGPDNNPLVVLNLSEPYPTMELQAIVPEVLKKIVTTYDMMMQSLKALIENADAVYEKIVHCQKAAMEFHEHLHSIGTKEGLKERKLQKAVESFTWNITILKGQADLLKYAKNETLENLKQIHFAAVSCGLNKPGTENSEAQKPRRSLEAIPEKASDENGD", "length": 1128 }, "evidence": [ { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8K3R3-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4", "gene_name": "Plcd4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSQIQDLLATDQDLLLMQEGTMMRKVRTKSWKKLRYFRLQNDGMTVWHGSQPESMPKPTFSISDVERIRKGQDSELLRYLVEEFPLEQGFTVVFHGRRPNLDLVANSVEEAQIWMRGLQLLVDLVASMDHQEQMDQMLNEWFQQADRNQDGRMSFREAQRLLLLMNVEMDEEYAFSLFQEADVTQSDDLGSEEFVQFYKALTKRTEIEEIFEDFSSDKQKLTLLEFVDFLRKEQKEKDHAPDLALELIDRYEPSENGRLLHVLSKDGFLKYLCSKDGNIFNSDCLPIYQDMTQPLSHYYINSSHNTYLVGDQLCGQSSVEGYIRALKRGCRCVEVDTWDGPDGEPVVYHGHTLTSRILFKDVLATLAQYAFQSSDYPLILSLENHCTWEQQRTMAHHLTEILGEQLLRNTLEGLLVDSMPSPEQLRGKILVKGKKLRTIEVDKEEEEEEEEEELEKDEGPDLDPASPELDTQPQPETQGQAAGNKKERKKKVMKCPMSCLLICGHVMAQAPSSIPESILLSKQFLLLSSTTIMCPDLSALVVYLRTVPFCSFTHSKENYHIYDISSFSESKAKNLIKEAGNEFVQHNARQLCRVYPSGLRTDSSNFNPQEHWNVGCQMVAMNMQTAGSAMDICDGLFRQNGGSGYVLKPEFLRDTQSSFNPERPISLYKAQILVVQVISGQQLPKVDKTKETTVVDPLVKVELYGVPEDTKEQETSHVENNGINPYWGETFYFRLQVPELAMLRFVVKDYSRKSRNNFIGQYTLPWTCMKQGYRHVSLLSRDGTSLNPASIFVYTCMQEDLDMDEP", "length": 807 }, "evidence": [ { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8K4D7-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1", "gene_name": "Plcz1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESQLHELAEARWFLSKVQDDFRGGKINVEITHKLLEKLDFPCHFAHVKHIFKENDRQNQGRITIEEFRAIYRCIVHREEITEIFNTYTENRKILSENSLIEFLTQEQYEMEIDHSDSVEIINKYEPIEEVKGERQMSIEGFARYMFSSECLLFKENCKTVYQDMNHPLSDYFISSSHNTYLISDQILGPSDIWGYVSALVKGCRCLEIDCWDGSQNEPIVYHGYTFTSKLLFKTVVQAINKYAFVTSDYPVVLSLENHCSPGQQEVMASILQSTFGDFLLSDMLEEFPDTLPSPEALKFKILVKNRKVGTLSETHERIGTDKSGQVLEWKEVIYEDGDEDSGMDPETWDVFLSRIKEEREADPSTLSGIAGVKKRKRKMKIAMALSDLVIYTKAEKFRNFQYSRVYQQFNETNSIGESRARKLSKLRVHEFIFHTAAFITRVYPKMMRADSSNFNPQEFWNVGCQMVALNFQTPGLPMDLQNGKFLDNGGSGYILKPDILRDTTLGFNPNEPEYDDHPVTLTIRIISGIQLPVSSSSNTPDIVVIIEVYGVPNDHVKQQTRVVKNNAFSPKWNETFTFLIQVPELALIRFVVETQQGLLSGNELLGQYTLPVLCMNKGYRRVPLFSKSGANLEPSSLFIYVWYFRE", "length": 647 }, "evidence": [ { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N3E9-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3", "gene_name": "PLCD3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLCGRWRRCRRPPEEPPVAAQVAAQVAAPVALPSPPTPSDGGTKRPGLRALKKMGLTEDEDVRAMLRGSRLRKIRSRTWHKERLYRLQEDGLSVWFQRRIPRAPSQHIFFVQHIEAVREGHQSEGLRRFGGAFAPARCLTIAFKGRRKNLDLAAPTAEEAQRWVRGLTKLRARLDAMSQRERLDHWIHSYLHRADSNQDSKMSFKEIKSLLRMVNVDMNDMYAYLLFKECDHSNNDRLEGAEIEEFLRRLLKRPELEEIFHQYSGEDRVLSAPELLEFLEDQGEEGATLARAQQLIQTYELNETAKQHELMTLDGFMMYLLSPEGAALDNTHTCVFQDMNQPLAHYFISSSHNTYLTDSQIGGPSSTEAYVRAFAQGCRCVELDCWEGPGGEPVIYHGHTLTSKILFRDVVQAVRDHAFTLSPYPVILSLENHCGLEQQAAMARHLCTILGDMLVTQALDSPNPEELPSPEQLKGRVLVKGKKLPAARSEDGRALSDREEEEEDDEEEEEEVEAAAQRRLAKQISPELSALAVYCHATRLRTLHPAPNAPQPCQVSSLSERKAKKLIREAGNSFVRHNARQLTRVYPLGLRMNSANYSPQEMWNSGCQLVALNFQTPGYEMDLNAGRFLVNGQCGYVLKPACLRQPDSTFDPEYPGPPRTTLSIQVLTAQQLPKLNAEKPHSIVDPLVRIEIHGVPADCARQETDYVLNNGFNPRWGQTLQFQLRAPELALVRFVVEDYDATSPNDFVGQFTLPLSSLKQGYRHIHLLSKDGASLSPATLFIQIRIQRS", "length": 789 }, "evidence": [ { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R3B1-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1", "gene_name": "Plcd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSGRDFLTLHGLQDDPDLQALLKGSQLLKVKSSSWRRERFYKLQEDCKTIWQESRKVMRSPESQLFSIEDIQEVRMGHRTEGLEKFARDIPEDRCFSIVFKDQRNTLDLIAPSPADVQHWVQGLRKIIDRSGSMDQRQKLQHWIHSCLRKADKNKDNKMNFKEVKDFLKELNVQVDDSYARKIFRECDHSQTDSLEDEEIETFYRMLTQRAEIDRAFAEAAGSAETLSVEKLVTFLQHQQREEEAGPALALSLIERYEPSETAKAQRQMTKDGFLMYLLSADGNAFSLAHRRVYQDMNQPLSHYLVSSSHNTYLLEDQLTGPSSTEAYIRALCKGCRCLELDCWDGPNQEPIIYHGYTFTSKILFCDVLRAIRDYAFKASPYPVILSLENHCSLEQQRVMAHHLRAILGPMLLDQPLDGVTTSLPSPEQLKEKILLKGKKLGGLLPAGGENGPEATDVSDEDEAAEMEDEAVRSQVQHKPKEDKLKLVPELSDMVIYCKSVHFGGFSSPSTSGQAFYEMASFSESRALRLLQESGNSFVRHNVGHLSRIYPAGWRTDSSNYSPVEMWNGGCQIVALNFQTPGPEMDVYLGCFQDNGGCGYVLKPAFLRDPDTTFNSRALTQGPWWAPKKLRVWIISGQQLPKVNKNKNSIVDPKVIVEIHGVGQDVASRQTAVITNNGFNPRWDTEFEFVVAVPDLALVRFMVEDYDSSSKNDFIGQSTIPWNSLKQGYRHVHLLSKNGDLHPSATLFVKISIQD", "length": 756 }, "evidence": [ { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q99JE6-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3", "gene_name": "Plcb3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGARPGVHALQLEPPTVVETLRRGSKFIKWDEEASSRNLVTLRLDPNGFFLYWTGPNMEVDTLDISSIRDTRTGRYARLPKDPKIREVLGFGGPDTRLEEKLMTVVAGPDPVNTTFLNFMAVQDDTVKVWSEELFKLAMNILAQNAPEHVLRKAYTKLKLQVNQDGRIPVKNILKMFSADKKRVETALICGLNFNRSESIRPDEFSLEIFERFLNKLLLRPDIDKILLEIGAKGKPYLTLEQLMDFINQKQRDPRLNEVLYPPLRSSQARLLIEKYEPNKQFLERDQMSMEGFSRYLGGEENGILPLEALDLSMDMTQPLSAYFINSSHNTYLTAGQLAGTSSVEMYRQALLWGCRCVELDVWKGRPPEEEPFITHGFTMTTEVPLRDVLEAIAETAFKTSPYPVILSFENHVDSAKQQAKMAEYCRSIFGEALLIDPLDKYPLSAGTPLPSPQDLMGRILVKNKKRHRPSTGVPDSSVAKRPLEQSNSALSESSAATEPSSPQLGSPSSDSCPGLSNGEEVGLEKTSLEPQKSLGEEGLNRGPNVLMPDRDREDEEEDEEEEETTDPKKPTTDEGTASSEVNATEEMSTLVNYVEPVKFKSFEASRKRNKCFEMSSFVETKAMEQLTKSPMEFVEYNKQQLSRIYPKGTRVDSSNYMPQLFWNVGCQLVALNFQTLDLPMQLNAGVFEYNGRSGYLLKPEFMRRPDKSFDPFTEVIVDGIVANALRVKVISGQFLSDRKVGIYVEVDMFGLPVDTRRKYRTRTSQGNSFNPVWDEEPFDFPKVVLPTLASLRIAAFEEGGRFVGHRILPVSAIRSGYHYVCLRNEANQPLCLPALLIYTEASDYIPDDHQDYAEALINPIKHVSLMDQRAKQLAALIGESEAQASTEMCQETPSQQQGSQLSSNPVPNPLDDSPRWPPGPTTSPTSTSLSSPGQRDDLIASILSEVTPTPLEELRSHKAMVKLRSRQDRDLRELHKKHQRKAVALTRRLLDGLAQARAEGKCRPSSSALSRATNVEDVKEEEKEAARQYREFQNRQVQSLLELREAQADAETERRLEHLKQAQQRLREVVLDAHTTQFKRLKELNEREKKELQKILDRKRNNSISEAKTREKHKKEVELTEINRRHITESVNSIRRLEEAQKQRHERLLAGQQQVLQQLVEEEPKLVAQLTQECQEQRERLPQEIRRCLLGETSEGLGDGPLVACASNGHAAGSGGHQSGADSESQEENTQL", "length": 1234 }, "evidence": [ { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9BRC7-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4", "gene_name": "PLCD4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASLLQDQLTTDQDLLLMQEGMPMRKVRSKSWKKLRYFRLQNDGMTVWHARQARGSAKPSFSISDVETIRNGHDSELLRSLAEELPLEQGFTIVFHGRRSNLDLMANSVEEAQIWMRGLQLLVDLVTSMDHQERLDQWLSDWFQRGDKNQDGKMSFQEVQRLLHLMNVEMDQEYAFSLFQAADTSQSGTLEGEEFVQFYKALTKRAEVQELFESFSADGQKLTLLEFLDFLQEEQKERDCTSELALELIDRYEPSDSGKLRHVLSMDGFLSYLCSKDGDIFNPACLPIYQDMTQPLNHYFICSSHNTYLVGDQLCGQSSVEGYIRALKRGCRCVEVDVWDGPSGEPVVYHGHTLTSRILFKDVVATVAQYAFQTSDYPVILSLETHCSWEQQQTMARHLTEILGEQLLSTTLDGVLPTQLPSPEELRRKILVKGKKLTLEEDLEYEEEEAEPELEESELALESQFETEPEPQEQNLQNKDKKKKSKPILCPALSSLVIYLKSVSFRSFTHSKEHYHFYEISSFSETKAKRLIKEAGNEFVQHNTWQLSRVYPSGLRTDSSNYNPQELWNAGCQMVAMNMQTAGLEMDICDGHFRQNGGCGYVLKPDFLRDIQSSFHPEKPISPFKAQTLLIQVISGQQLPKVDKTKEGSIVDPLVKVQIFGVRLDTARQETNYVENNGFNPYWGQTLCFRVLVPELAMLRFVVMDYDWKSRNDFIGQYTLPWTCMQQGYRHIHLLSKDGISLRPASIFVYICIQEGLEGDES", "length": 762 }, "evidence": [ { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9NQ66-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1", "gene_name": "PLCB1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGAQPGVHALQLKPVCVSDSLKKGTKFVKWDDDSTIVTPIILRTDPQGFFFYWTDQNKETELLDLSLVKDARCGRHAKAPKDPKLRELLDVGNIGRLEQRMITVVYGPDLVNISHLNLVAFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSADRKRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKPYLTVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLARKGQISVDGFMRYLSGEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKKKLSEQASNTYSDSSSMFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEMSNLVNYIQPVKFESFEISKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPEFMRRPDKHFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQGNAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEGGKFIGHRILPVQAIRPGYHYICLRNERNQPLTLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKKEADPGETPSEAPSEARTTPAENGVNHTTTLTPKPPSQALHSQPAPGSVKAPAKTEDLIQSVLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYLRRRAALEKSAKKDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKITEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKPKLQVELEQEYQDKFKRLPLEILEFVQEAMKGKISEDSNHGSAPLSLSSDPGKVNHKTPSSEELGGDIPGKEFDTPL", "length": 1216 }, "evidence": [ { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QW07-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4", "gene_name": "Plcb4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKPYEFNWQKEVPSFLQEGAVFDRYEEESFVFEPNCLFKVDEFGFFLTWKSEGKEGQVLECSLINSIRLAAIPKDPKILAALESVGKSENDLEGRILCVCSGTDLVNIGFTYMVAENPEITKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFLTNTSGKIPVRSITRTFASGKTEKVIFQALKELGLPSGKNDEIEPAAFTYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMYEPDEELKKKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYQMSKYCEDLFGDLLLKQALESHPLEPGRLLPSPNDLKRKILIKNKRLKPEVEKKQLEALKSMMEAGESAAPASILEDDNEEEIESADQEEEAHPEYKFGNELSADDFSHKEAVANSVKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQLRAMGIETSDIADVPSDTSKNDKKGKANPAKANVTPQSSSELRPTTTAALGSGQEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKEHSTMQKLHCTQVDKIVAQYDKEKSTHEKILEKAMKKKGGSNCLEIKKETEIKIQTLTSDHKSKVKEIVAQHTKEWSEMINTHSAEEQEIRDLHLSQQCELLRKLLINAHEQQTQQLKLSHDRESKEMRAHQAKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMKQSKEMDQLKKVQLEHLEFLEKQNEQAKEMQQMVKLEAEMDRRPATVV", "length": 1175 }, "evidence": [ { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9UPR0-1", "protein_name": "Inactive phospholipase C-like protein 2", "gene_name": "PLCL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAECGRGGAAGGALPTSPGPALGAKGALKAGVGEGGGGGGRLGHGRARYDSGGVSNGDCSLGVSGDEARASPTRGPRGVALAPTPSAVVCTLPRESKPGGLPRRSSIIKDGTKQKRERKKTVSFSSMPTEKKISSASDCINSMVEGSELKKVRSNSRIYHRYFLLDADMQSLRWEPSKKDSEKAKIDIKSIKEVRTGKNTDIFRSNGISDQISEDCAFSVIYGENYESLDLVANSADVANIWVTGLRYLISYGKHTLDMLESSQDNMRTSWVSQMFSEIDVDNLGHITLCNAVQCIRNLNPGLKTSKIELKFKELHKSKDKAGTEVTKEEFIEVFHELCTRPEIYFLLVQFSSNKEFLDTKDLMMFLEAEQGVAHINEEISLEIIHKYEPSKEGQEKGWLSIDGFTNYLMSPDCYIFDPEHKKVCQDMKQPLSHYFINSSHNTYLIEDQFRGPSDITGYIRALKMGCRSVELDVWDGPDNEPVIYTGHTMTSQIVFRSVIDIINKYAFFASEYPLILCLENHCSIKQQKVMVQHMKKLLGDKLYTTSPNVEESYLPSPDVLKGKILIKAKKLSSNCSGVEGDVTDEDEGAEMSQRMGKENMEQPNNVPVKRFQLCKELSELVSICKSVQFKEFQVSFQVQKYWEVCSFNEVLASKYANENPGDFVNYNKRFLARVFPSPMRIDSSNMNPQDFWKCGCQIVAMNFQTPGLMMDLNIGWFRQNGNCGYVLRPAIMREEVSFFSANTKDSVPGVSPQLLHIKIISGQNFPKPKGSGAKGDVVDPYVYVEIHGIPADCAEQRTKTVHQNGDAPIFDESFEFQINLPELAMVRFVVLDDDYIGDEFIGQYTIPFECLQTGYRHVPLQSLTGEVLAHASLFVHVAITNRRGGGKPHKRGLSVRKGKKSREYASLRTLWIKTVDEVFKNAQPPIRDATDLRENMQNAVVSFKELCGLSSVANLMQCMLAVSPRFLGPDNTPLVVLNLSEQYPTMELQGIVPEVLKKIVTTYDMMIQSLKALIENADAVYEKIVHCQKAAMEFHEHLHSIGTKEGLKERKLQKAVESFTWNITILKGQADLLKYAKNETLENLKQIHFAAVSCGLNKPGTENADVQKPRRSLEVIPEKANDETGE", "length": 1127 }, "evidence": [ { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z1B3-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1", "gene_name": "Plcb1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGAQPGVHALQLKPVCVSDSLKKGTKFVKWDDDSTIVTPIILRTDPQGFFFYWTDQNKETELLDLSLVKDARCGKHAKAPKDPKLRELLDVGNIGHLEQRMITVVYGPDLVNISHLNLVAFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSADRKRVETALEACSLPSSRNDSIPQEDFTPDVYRVFLNNLCPRPEIDNIFSEFGAKSKPYLTVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNSSLAKKGQMSVDGFMRYLSGEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKKKLSEQASNTYSDSSSVFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEMSNLVNYIQPVKFESFEISKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTVDLAMQINMGMYEYNGKSGYRLKPEFMRRPDKHFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQGNAVNPVWEEEPIVFKKVVLPSLACLRIAAYEEGGKFIGHRILPVQAIRPGYHYICLRNERNQPLTLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEEVKKEADPGETSSEAPSETRTTPAENGVNHTASLAPKPPSQAPHSQPAPGSVKAPAKTEDLIQSVLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTELIKEHTTKYNEIQNDYLRRRAALEKSAKKDSKKKSEPSSPDHGSSAIEQDLAALDAEMTQKLIDLKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKITEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHNEIRQQILDEKPKLQTELEQEYQDKFKRLPLEILEFVQEAMKGKISEDSNHGSAPPSLASDAAKVNLKSPSSEEIERENPGREFDTPL", "length": 1216 }, "evidence": [ { "id": "SGD:S000006189", "url": "https://alliancegenome.org/gene/SGD:S000006189#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphatidylinositol-4,5-bisphosphate phospholipase C activity", "id": "GO:0004435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004435", "evidence": [ { "database": "UniProtKB", "id": "Q9VXH3", "url": "https://www.uniprot.org/uniprotkb/Q9VXH3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 15, "go_terms": [ { "name": "positive regulation of cell growth", "id": "GO:0030307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030307", "evidence": [ { "database": "UniProtKB", "id": "Q9VXH3", "url": "https://www.uniprot.org/uniprotkb/Q9VXH3" } ], "pmid": "" }, { "name": "phospholipid catabolic process", "id": "GO:0009395", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009395", "evidence": [ { "database": "UniProtKB", "id": "Q9VXH3", "url": "https://www.uniprot.org/uniprotkb/Q9VXH3" } ], "pmid": "" }, { "name": "response to insulin", "id": "GO:0032868", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032868", "evidence": [ { "database": "UniProtKB", "id": "Q9VXH3", "url": "https://www.uniprot.org/uniprotkb/Q9VXH3" } ], "pmid": "" }, { "name": "release of sequestered calcium ion into cytosol", "id": "GO:0051209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051209", "evidence": [ { "database": "UniProtKB", "id": "Q9VXH3", "url": "https://www.uniprot.org/uniprotkb/Q9VXH3" } ], "pmid": "" }, { "name": "negative regulation of ERK1 and ERK2 cascade", "id": "GO:0070373", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070373", "evidence": [ { "database": "UniProtKB", "id": "Q9VXH3", "url": "https://www.uniprot.org/uniprotkb/Q9VXH3" } ], "pmid": "" }, { "name": "phosphatidylinositol-mediated signaling", "id": "GO:0048015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048015", "evidence": [ { "database": "UniProtKB", "id": "Q9VXH3", "url": "https://www.uniprot.org/uniprotkb/Q9VXH3" } ], "pmid": "" }, { "name": "negative regulation of cell differentiation", "id": "GO:0045596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045596", "evidence": [ { "database": "UniProtKB", "id": "Q9VXH3", "url": "https://www.uniprot.org/uniprotkb/Q9VXH3" } ], "pmid": "" }, { "name": "negative regulation of epidermal growth factor receptor signaling pathway", "id": "GO:0042059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042059", "evidence": [ { "database": "UniProtKB", "id": "Q9VXH3", "url": "https://www.uniprot.org/uniprotkb/Q9VXH3" } ], "pmid": "" }, { "name": "positive regulation of epithelial cell migration", "id": "GO:0010634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010634", "evidence": [ { "database": "UniProtKB", "id": "Q9VXH3", "url": "https://www.uniprot.org/uniprotkb/Q9VXH3" } ], "pmid": "" }, { "name": "phosphatidylinositol metabolic process", "id": "GO:0046488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046488", "evidence": [ { "database": "UniProtKB", "id": "Q9VXH3", "url": "https://www.uniprot.org/uniprotkb/Q9VXH3" } ], "pmid": "" }, { "name": "anatomical structure morphogenesis", "id": "GO:0009653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009653", "evidence": [ { "database": "UniProtKB", "id": "Q9VXH3", "url": "https://www.uniprot.org/uniprotkb/Q9VXH3" } ], "pmid": "" }, { "name": "border follicle cell migration", "id": "GO:0007298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007298", "evidence": [ { "database": "UniProtKB", "id": "Q9VXH3", "url": "https://www.uniprot.org/uniprotkb/Q9VXH3" } ], "pmid": "" }, { "name": "negative regulation of crystal cell differentiation", "id": "GO:0042690", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042690", "evidence": [ { "database": "UniProtKB", "id": "Q9VXH3", "url": "https://www.uniprot.org/uniprotkb/Q9VXH3" } ], "pmid": "" }, { "name": "negative regulation of R7 cell differentiation", "id": "GO:0045677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045677", "evidence": [ { "database": "UniProtKB", "id": "Q9VXH3", "url": "https://www.uniprot.org/uniprotkb/Q9VXH3" } ], "pmid": "" }, { "name": "negative regulation of sevenless signaling pathway", "id": "GO:0045873", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045873", "evidence": [ { "database": "UniProtKB", "id": "Q9VXH3", "url": "https://www.uniprot.org/uniprotkb/Q9VXH3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "ruffle membrane", "id": "GO:0032587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032587", "evidence": [ { "database": "UniProtKB", "id": "Q9VXH3", "url": "https://www.uniprot.org/uniprotkb/Q9VXH3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1161, "end_pos": 1163, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1232, "end_pos": 1234, "annotation": "n_glycosylation_sequon" }, { "start_pos": 420, "end_pos": 422, "annotation": "n_glycosylation_sequon" }, { "start_pos": 546, "end_pos": 548, "annotation": "n_glycosylation_sequon" }, { "start_pos": 649, "end_pos": 651, "annotation": "n_glycosylation_sequon" }, { "start_pos": 705, "end_pos": 707, "annotation": "n_glycosylation_sequon" }, { "start_pos": 826, "end_pos": 828, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "33179", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P25455-3", "P13217-1", "Q9VXH3-1" ], "evidence": [ { "id": "33179", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/33179" } ] }, { "id": "R-DME-114689", "name": "PLC gamma 2-mediated PIP2 hydrolysis", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VXH3-1" ], "evidence": [ { "id": "R-DME-114689", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-114689" } ] }, { "id": "R-DME-1524182", "name": "Activated PLC gamma dissociates from the PDGF receptor", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1JHB7-1", "Q9VXH3-1" ], "evidence": [ { "id": "R-DME-1524182", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1524182" } ] }, { "id": "R-DME-1524186", "name": "Phosphorylation of PLCgamma by PDGFR", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1JHB7-1", "Q9VXH3-1" ], "evidence": [ { "id": "R-DME-1524186", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1524186" } ] }, { "id": "R-DME-1855221", "name": "PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VXH3-1" ], "evidence": [ { "id": "R-DME-1855221", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1855221" } ] }, { "id": "R-DME-186765", "name": "PLC-gamma binds to the active receptor", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1JHB7-1", "Q9VXH3-1" ], "evidence": [ { "id": "R-DME-186765", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-186765" } ] }, { "id": "R-DME-202354", "name": "Translocation of PLC-gamma1 to PIP2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VXH3-1" ], "evidence": [ { "id": "R-DME-202354", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-202354" } ] }, { "id": "R-DME-202407", "name": "PLC-gamma1 hydrolyses PIP2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VXH3-1" ], "evidence": [ { "id": "R-DME-202407", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-202407" } ] }, { "id": "R-DME-212706", "name": "Phospholipase C-gamma1 binds to the activated EGF receptor", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P04412-1", "Q9VXH3-1" ], "evidence": [ { "id": "R-DME-212706", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-212706" } ] }, { "id": "R-DME-212710", "name": "EGFR activates PLC-gamma1 by phosphorylation", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P04412-1", "Q9VXH3-1" ], "evidence": [ { "id": "R-DME-212710", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-212710" } ] }, { "id": "R-DME-212713", "name": "Active PLC-gamma1 dissociates from EGFR", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P04412-1", "Q9VXH3-1" ], "evidence": [ { "id": "R-DME-212713", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-212713" } ] }, { "id": "R-DME-2424476", "name": "Activation of RAC1 by VAV2/3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P08630-1", "P40792-1", "Q9VXH3-1" ], "evidence": [ { "id": "R-DME-2424476", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-2424476" } ] }, { "id": "R-DME-2424485", "name": "Release of p-PLCG1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P08630-1", "Q9VXH3-1" ], "evidence": [ { "id": "R-DME-2424485", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-2424485" } ] }, { "id": "R-DME-2424487", "name": "Phosphorylation of PLC-gamma by p-BTK/p-SYK", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P08630-1", "Q9VXH3-1" ], "evidence": [ { "id": "R-DME-2424487", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-2424487" } ] }, { "id": "R-DME-2730840", "name": "Activation of RAC1 by VAV", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P40792-1", "Q9VXH3-1" ], "evidence": [ { "id": "R-DME-2730840", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-2730840" } ] }, { "id": "R-DME-2730841", "name": "Phosphorylation and activation of VAV", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VXH3-1" ], "evidence": [ { "id": "R-DME-2730841", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-2730841" } ] }, { "id": "R-DME-2730847", "name": "Hydrolysis of PIP2 by PLCG", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P08630-1", "Q9VXH3-1" ], "evidence": [ { "id": "R-DME-2730847", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-2730847" } ] }, { "id": "R-DME-2730856", "name": "Autophosphorylation of PAK", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P40792-1", "A0A0B4KGS4-1", "Q9VI13-1", "Q9VXH3-1" ], "evidence": [ { "id": "R-DME-2730856", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-2730856" } ] }, { "id": "R-DME-2730858", "name": "Autophosphorylation of BTK/ITK", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P08630-1", "Q9VXH3-1" ], "evidence": [ { "id": "R-DME-2730858", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-2730858" } ] }, { "id": "R-DME-2730889", "name": "Recruitment of PAK to the membrane by binding active RAC1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P40792-1", "A0A0B4KGS4-1", "Q9VI13-1", "Q9VXH3-1" ], "evidence": [ { "id": "R-DME-2730889", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-2730889" } ] }, { "id": "R-DME-429497", "name": "SLP-76 stimulates PLC gamma 2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [ "R-DME-114601" ], "output_participant_list": [ "R-DME-114602" ], "enzyme_list": [ "Q9VXH3-1" ], "evidence": [ { "id": "R-DME-429497", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-429497" } ] }, { "id": "R-DME-5607735", "name": "p-Y753,Y759-PLCG2 hydrolyses PIP2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VXH3-1" ], "evidence": [ { "id": "R-DME-5607735", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-5607735" } ] }, { "id": "R-DME-5607755", "name": "p-Y753,Y759-PLCG2 translocates from cytosol to plasma membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [ "R-DME-5607631" ], "output_participant_list": [ "R-DME-5607640" ], "enzyme_list": [ "Q9VXH3-1" ], "evidence": [ { "id": "R-DME-5607755", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-5607755" } ] }, { "id": "R-DME-5654147", "name": "Activated FGFR2 phosphorylates PLCG1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q07407-1", "Q09147-1", "Q9VXH3-1" ], "evidence": [ { "id": "R-DME-5654147", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-5654147" } ] }, { "id": "R-DME-5654148", "name": "p-4Y-PLCG1 dissociates from activated FGFR3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q07407-1", "Q09147-1", "Q9VXH3-1" ], "evidence": [ { "id": "R-DME-5654148", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-5654148" } ] }, { "id": "R-DME-5654149", "name": "Activated FGFR1 phosphorylates PLCG1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q09147-1", "Q9VV98-1", "Q9VXH3-1" ], "evidence": [ { "id": "R-DME-5654149", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-5654149" } ] }, { "id": "R-DME-5654151", "name": "Activated FGFR4 phosphorylates PLCG1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q07407-1", "Q09147-1", "Q9VV98-1", "Q9VXH3-1" ], "evidence": [ { "id": "R-DME-5654151", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-5654151" } ] }, { "id": "R-DME-5654157", "name": "p-4Y-PLCG1 dissociates from activated FGFR2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q07407-1", "Q09147-1", "Q9VXH3-1" ], "evidence": [ { "id": "R-DME-5654157", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-5654157" } ] }, { "id": "R-DME-5654159", "name": "Activated FGFR2 binds PLCG1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q07407-1", "Q09147-1", "Q9VXH3-1" ], "evidence": [ { "id": "R-DME-5654159", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-5654159" } ] }, { "id": "R-DME-5654163", "name": "Activated FGFR4 binds PLCG1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q07407-1", "Q09147-1", "Q9VV98-1", "Q9VXH3-1" ], "evidence": [ { "id": "R-DME-5654163", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-5654163" } ] }, { "id": "R-DME-5654165", "name": "p-4Y-PLCG1 dissociates from activated FGFR1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q09147-1", "Q9VV98-1", "Q9VXH3-1" ], "evidence": [ { "id": "R-DME-5654165", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-5654165" } ] }, { "id": "R-DME-5654167", "name": "Activated FGFR1 binds PLCG1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q09147-1", "Q9VV98-1", "Q9VXH3-1" ], "evidence": [ { "id": "R-DME-5654167", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-5654167" } ] }, { "id": "R-DME-5654169", "name": "p-4Y-PLCG1 dissociates from activated FGFR4", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, extracellular region, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q07407-1", "Q09147-1", "Q9VV98-1", "Q9VXH3-1" ], "evidence": [ { "id": "R-DME-5654169", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-5654169" } ] }, { "id": "R-DME-5654222", "name": "Activated FGFR3 phosphorylates PLCG1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q07407-1", "Q09147-1", "Q9VXH3-1" ], "evidence": [ { "id": "R-DME-5654222", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-5654222" } ] }, { "id": "R-DME-5654224", "name": "Activated FGFR3 binds PLCG1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q07407-1", "Q09147-1", "Q9VXH3-1" ], "evidence": [ { "id": "R-DME-5654224", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-5654224" } ] } ], "reaction_participants": [ { "participant_id": "R-DME-114601", "participant_name": "sl [plasma membrane]", "crossref": [ { "id": "Q9VXH3", "database": "UniProt", "url": "" }, { "id": "FBgn0003416", "database": "FlyBase", "url": "" }, { "id": "NP_476726.2", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-DME-114602", "participant_name": "phospho-sl [plasma membrane]", "crossref": [ { "id": "FBgn0003416", "database": "FlyBase", "url": "" }, { "id": "Q9VXH3", "database": "UniProt", "url": "" }, { "id": "NP_476726.2", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-DME-5607631", "participant_name": "phospho-sl [cytosol]", "crossref": [ { "id": "Q9VXH3", "database": "UniProt", "url": "" }, { "id": "FBgn0003416", "database": "FlyBase", "url": "" }, { "id": "NP_476726.2", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-DME-5607640", "participant_name": "phospho-sl [plasma membrane]", "crossref": [ { "id": "Q9VXH3", "database": "UniProt", "url": "" }, { "id": "NP_476726.2", "database": "RefSeq", "url": "" }, { "id": "FBgn0003416", "database": "FlyBase", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A0B4KGS4", "gene_name": "Pak3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A0B4KGS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A0B4KGS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KGS4" } ] } ] }, { "uniprot_ac": "E1JHB7", "gene_name": "Pvr", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1JHB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1JHB7" } ] } ] }, { "uniprot_ac": "P04412", "gene_name": "Egfr", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P04412", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04412" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P04412", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04412" } ] } ] }, { "uniprot_ac": "P08630", "gene_name": "Btk", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P08630", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08630" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "P08630", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08630" } ] } ] }, { "uniprot_ac": "P13217", "gene_name": "norpA", "activity": [ { "ec_number": "3.1.4.11", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+).", "evidence": [ { "id": "P13217", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13217" } ] }, { "ec_number": "3.1.4.11", "activity": "", "evidence": [ { "id": "P13217", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13217" } ] } ] }, { "uniprot_ac": "P25455", "gene_name": "Plc21C", "activity": [ { "ec_number": "3.1.4.11", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+).", "evidence": [ { "id": "P25455", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P25455" } ] }, { "ec_number": "3.1.4.11", "activity": "", "evidence": [ { "id": "P25455", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P25455" } ] } ] }, { "uniprot_ac": "P40792", "gene_name": "Rac1", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "P40792", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P40792" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "P40792", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P40792" } ] } ] }, { "uniprot_ac": "Q07407", "gene_name": "htl", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q07407", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07407" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q07407", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07407" } ] } ] }, { "uniprot_ac": "Q09147", "gene_name": "btl", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q09147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q09147" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "Q09147", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q09147" } ] } ] }, { "uniprot_ac": "Q9VI13", "gene_name": "Pak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9VI13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VI13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q9VI13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VI13" } ] } ] }, { "uniprot_ac": "Q9VV98", "gene_name": "Dmel\\CG9701", "activity": [ { "ec_number": "3.2.1.21", "activity": "Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.", "evidence": [ { "id": "Q9VV98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VV98" } ] }, { "ec_number": "3.2.1.46", "activity": "a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O = an N-acylsphing-4-enine + D-galactose.", "evidence": [ { "id": "Q9VV98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VV98" } ] }, { "ec_number": "3.2.1.21", "activity": "", "evidence": [ { "id": "Q9VV98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VV98" } ] }, { "ec_number": "3.2.1.46", "activity": "", "evidence": [ { "id": "Q9VV98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VV98" } ] } ] }, { "uniprot_ac": "Q9VXH3", "gene_name": "sl", "activity": [ { "ec_number": "3.1.4.11", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+).", "evidence": [ { "id": "Q9VXH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXH3" } ] }, { "ec_number": "3.1.4.11", "activity": "", "evidence": [ { "id": "Q9VXH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXH3" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VXH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXH3" }, { "id": "PS50004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2", "eco_id": "ECO_0000259", "start_pos": 1092, "end_pos": 1213, "start_aa": "Lys", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q9VXH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXH3" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 20, "end_pos": 138, "start_aa": "Gly", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q9VXH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXH3" }, { "id": "PS50008", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50008" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PI-PLC Y-box", "eco_id": "ECO_0000259", "start_pos": 980, "end_pos": 1092, "start_aa": "Met", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q9VXH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXH3" }, { "id": "PS50001", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50001" } ], "ann_type": "Domain_Extent_Annotation", 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"https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.4.11" } ] } ], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1161, "end_pos": 1163 }, { "start_pos": 1232, "end_pos": 1234 }, { "start_pos": 420, "end_pos": 422 }, { "start_pos": 546, "end_pos": 548 }, { "start_pos": 649, "end_pos": 651 }, { "start_pos": 705, "end_pos": 707 }, { "start_pos": 826, "end_pos": 828 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VXK5-1", "uniprot_ac": "Q9VXK5", "uniprot_id": "Q9VXK5_DROME", "mass": { "chemical_mass": 93347.0, "monoisotopic_mass": 93347.0 }, "refseq": { "ac": "NP_573099", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573099" }, "gene_names": [ { "name": "dSpb1", "type": "recommended", "evidence": [ { "id": "Q9VXK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXK5" } ] }, { "name": "CG8939", "type": "synonym", "evidence": [ { "id": "NP_573099", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573099" }, { "id": "Q9VXK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXK5" } ] }, { "name": "Dmel\\CG8939", "type": "synonym", "evidence": [ { "id": "NP_573099", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573099" }, { "id": "Q9VXK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXK5" } ] }, { "name": "Dmel_CG8939", "type": "synonym", "evidence": [ { "id": "Q9VXK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXK5" } ] }, { "name": "dSpb1", "type": "synonym", "evidence": [ { "id": "NP_573099", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573099" } ] } ], "protein_names": [ { "name": "Putative rRNA methyltransferase", "type": "recommended", "evidence": [ { "id": "Q9VXK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXK5/entry#names_and_taxonomy" } ] }, { "name": "2'-O-ribose RNA methyltransferase SPB1 homolog", "type": "synonym", "evidence": [ { "id": "Q9VXK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXK5/entry#names_and_taxonomy" } ] }, { "name": "2.1.1.-", "type": "synonym", "evidence": [ { "id": "Q9VXK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXK5/entry#names_and_taxonomy" } ] }, { "name": "CG8939-PA", "type": "synonym", "evidence": [ { "id": "NP_573099", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573099" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_573099", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573099" } ] } ], "function": [ { "annotation": "Probable methyltransferase involved in the maturation of rRNA and in the biogenesis of ribosomal subunits.", "evidence": [ { "database": "UniProtKB", "id": "Q9VXK5", "url": "https://www.uniprot.org/uniprotkb/Q9VXK5#function" }, { "database": "HAMAP", "id": "MF_03163", "url": "https://hamap.expasy.org/signature/MF_03163" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VXK5", "url": "https://www.uniprot.org/uniprotkb/Q9VXK5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "dSpb1", "url": "https://www.uniprot.org/uniprotkb/Q9VXK5", "locus": { "chromosome": "X", "start_pos": 15999698, "end_pos": 15997016, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0030720", "url": "https://www.ensemblgenomes.org/id/FBgn0030720" } ] } } ], "crossref": [ { "id": "FB:FBgn0030720", "url": "https://alliancegenome.org/gene/FB:FBgn0030720", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0030720", "url": "https://bgee.org/?page=gene&gene_id=FBgn0030720", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0030720", "url": "https://flybase.org/reports/FBgn0030720", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "32568", "url": "https://www.ncbi.nlm.nih.gov/gene/32568", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012920", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012920", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015507", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015507", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024576", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024576", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028589", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050082", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050082", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG8939", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG8939", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QRKDKYY", "url": "https://omabrowser.org/oma/group/QRKDKYY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VXK5", "url": "https://www.orthodb.org/?gene=Q9VXK5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10920", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10920", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10920:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10920:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01728", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01728", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07780", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07780", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11861", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11861", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6791226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_573099", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573099", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "48628", "url": "https://www.rhea-db.org/rhea/48628", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q9VXK5", "url": "https://www.uniprot.org/uniprotkb/Q9VXK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VXK5-1", "url": "https://www.uniprot.org/uniprotkb/Q9VXK5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGKKTKVGKTRKDKFYQLAKETGLRSRAAFKLIQLNRKFGFLQQSQVCLDLCAAPGGWMQVAKQNMPVSSIVIGVDLFPIRPIAGCIGLVEDITTEKCRQSLTKELQSWKADVVLHDGAPNVGRNWLYDAYQQICLTLNALKLSTQFLRNGGWFVTKVFRSKDYNALLWVLKQLFKKVHATKPSASRKESAEIFVVCQGYLAPDHIDPRLLDSKYVFEELDLDAKKKSSLLHPEKQKRIKAEGYTAQDIALRNDLAATEFLKAENALAALQGIGSIRIDDQRIANHKKTTPEILECCKDLKVLGRKDIKGLVQWWKDVRELFVEKETPLVVGNAADEKPKPLTQAEIEDMEDAELQTQIETIVEEEKKDLKRKRKKTLKTKAKLHEKMNLNMVIKGDDGPVEEMEHEIFDLKNIRTSAELDELLDVQPDFAVDESQPEETKLPKYKYFDKDEGNINDDLNYDDDNDEEQSEASDDEDQINDKQGLGLSDDDNDEGNAKGKNKRKKRSENPLIKSNDFRDKNTKREQRVQLWYEKDVLQNIQSDDDEETYDLNNLAKEFKAKGVAVLGESTLTPDANEEVVQGKKAKRRARHETATKDSSSESSESEDDANEDSDGEQPAAGTNAKKVRLSENEMALGALLTRSKKTRRDLIDAAWNRYAFNDENVPVWFKLDEDEHMTKPTPVPKELTAEYQRKLQEVNVRPIKKVMEAKARKHRRATKRLAKAKKMAEKIMENSDATNHEKSKQLKKVYKKAQEKKKEVTYVVAKKQTAARRARRPAGVKGRYKVVDPREKKDKRSMDAKKRREKGSKGRKGKGRK", "length": 817, "header": "tr|Q9VXK5-1|Q9VXK5_DROME Isoform 1 of Putative rRNA methyltransferase OS=Drosophila melanogaster OX=7227 GN=dSpb1 PE=1 SV=1 CANONICAL=Q9VXK5-1" }, "isoforms": [ { "isoform_ac": "Q9VXK5-1", "url": "https://www.uniprot.org/uniprotkb/Q9VXK5/entry#Q9VXK5-1", "sequence": { "sequence": "MGKKTKVGKTRKDKFYQLAKETGLRSRAAFKLIQLNRKFGFLQQSQVCLDLCAAPGGWMQVAKQNMPVSSIVIGVDLFPIRPIAGCIGLVEDITTEKCRQSLTKELQSWKADVVLHDGAPNVGRNWLYDAYQQICLTLNALKLSTQFLRNGGWFVTKVFRSKDYNALLWVLKQLFKKVHATKPSASRKESAEIFVVCQGYLAPDHIDPRLLDSKYVFEELDLDAKKKSSLLHPEKQKRIKAEGYTAQDIALRNDLAATEFLKAENALAALQGIGSIRIDDQRIANHKKTTPEILECCKDLKVLGRKDIKGLVQWWKDVRELFVEKETPLVVGNAADEKPKPLTQAEIEDMEDAELQTQIETIVEEEKKDLKRKRKKTLKTKAKLHEKMNLNMVIKGDDGPVEEMEHEIFDLKNIRTSAELDELLDVQPDFAVDESQPEETKLPKYKYFDKDEGNINDDLNYDDDNDEEQSEASDDEDQINDKQGLGLSDDDNDEGNAKGKNKRKKRSENPLIKSNDFRDKNTKREQRVQLWYEKDVLQNIQSDDDEETYDLNNLAKEFKAKGVAVLGESTLTPDANEEVVQGKKAKRRARHETATKDSSSESSESEDDANEDSDGEQPAAGTNAKKVRLSENEMALGALLTRSKKTRRDLIDAAWNRYAFNDENVPVWFKLDEDEHMTKPTPVPKELTAEYQRKLQEVNVRPIKKVMEAKARKHRRATKRLAKAKKMAEKIMENSDATNHEKSKQLKKVYKKAQEKKKEVTYVVAKKQTAARRARRPAGVKGRYKVVDPREKKDKRSMDAKKRREKGSKGRKGKGRK", "length": 817, "header": "tr|Q9VXK5-1|Q9VXK5_DROME Isoform 1 of Putative rRNA methyltransferase OS=Drosophila melanogaster OX=7227 GN=dSpb1 PE=1 SV=1 CANONICAL=Q9VXK5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VXK5", "url": "https://www.uniprot.org/uniprotkb/Q9VXK5" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VXK5", "url": "https://www.uniprot.org/uniprotkb/Q9VXK5" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXK5", "url": "https://www.uniprot.org/uniprotkb/Q9VXK5" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXK5", "url": "https://www.uniprot.org/uniprotkb/Q9VXK5" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VXK5", "url": "https://www.uniprot.org/uniprotkb/Q9VXK5" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VXK5", "url": "https://www.uniprot.org/uniprotkb/Q9VXK5" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VXK5", "url": "https://www.uniprot.org/uniprotkb/Q9VXK5" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXK5", "url": "https://www.uniprot.org/uniprotkb/Q9VXK5" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXK5", "url": "https://www.uniprot.org/uniprotkb/Q9VXK5" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VXK5", "url": "https://www.uniprot.org/uniprotkb/Q9VXK5" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VXK5", "url": "https://www.uniprot.org/uniprotkb/Q9VXK5" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG8939", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG8939", "resource": "KEGG Pathway" }, { "id": "R-DME-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AC58IDS8-1", "protein_name": "pre-rRNA processing protein FTSJ3", "gene_name": "ftsj3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGKKLKVGKTRKDKFYHLAKETGYRSRSSFKLIQLNRKFQFLQKARALVDLCAAPGGWLQVASKFMPVSSLVIGVDLVPIKPIPNVVTLQEDITTEKCRQALRKELQTWKVDVVLNDGAPNVGANWQHDAFSQANLTLMALKLACEFLAKGGTFITKVFRSKDYQPLMWIFQQFFKKVQATKPQASRNESAEIFVVCQGFLAPDKIDNKFFDPKHAFKEVDVQVKTVKELVNKKKPKAEGYSDGDLTLYHKFTITEFLKAENPVDFLSKANEITFDDPLLESHPLTSAEIRECCSDVKVLGRKELRLLLSWRSKLRKFLAKKLRQEAKQLDQEASSDDEQSDTDEKESKKKKSEEKKEEEDEDEAMEKKLTELKAEEFAELKRKKKKLLKERRKQRERVELKMDLPGVSIADAGDSSMFSLGSIRKSQGLHQLAQGDMSAADALLEDDEQEDVHLSDEEQEDERMSLASDLDSDDLQEIQQKEEQMLKNKPKKKKKVSFEQQDDGDEDNKNELLVELEGKDERKERETSMWFSKDIFAELDLNDDTDAMNELKQTQILQTGRGKKRKAQQEEEAEPKKPEQKVATPSQEVKEAEDSDSDDSSDDEREIAQMKQASAAVGTNGAEENDNIQVIPVEKTNKRARVLDAEGLALGAQIATSKKRERDLIDGSFHRFANSEDMTEVPAWFVDDEKKHRKRPVPVTKDMVEEYKQKWKEINARPIRRVAEAKARKKRRTLKKMEQAKKKAEAVVNTVDISEREKMAQLKSIYKKAGVGKEKREVTYVVAKKGVGRRVRRPAGVKGAFKVVDGRMKKDTRAAQRKDERGRGKGGRGSKGMKGGRGPKGGRGMKAGKGRPNKK", "length": 856 }, "evidence": [ { "id": "MGI:1860295", "url": "https://alliancegenome.org/gene/MGI:1860295#orthology", "database": "AGR" }, { "id": "HGNC:17136", "url": "https://alliancegenome.org/gene/HGNC:17136#orthology", "database": "AGR" }, { "id": "Q9VXK5", "url": "https://omabrowser.org/oma/group/Q9VXK5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1MY97-1", "protein_name": "pre-rRNA processing protein FTSJ3", "gene_name": "FTSJ3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGKKSKVGKSRRDKFYHLAKETGYRSRSAFKLIQLNRRFQFLQKARALLDLCAAPGGWLQVAAKFMPVSSLIVGVDLVPIKPLPNVVTLQEDITTERCRQALRKELKTWKVDVVLNDGAPNVGASWAHDAYSQAHLTLMALRLACDFLGRGGCFITKVFRSRDYQPLLWIFQQLFRRVQATKPQASRHESAEIFVVCQGFLAPDKVDSKFFDPKFAFKEVEVQAKTVTELVTKKKPKAEGYAEGDLTLYHRTSVTDFLRAANPVDFLSKASEISLDDEELAQHPATTEDIRVCCQDIKVLGRKELRSLLNWRTKLRRYVAKKLKEQAKALDISLSSGEEEEGEEEEAAAGTGPQPSQEEEEEEEQLNRTLAEMKAQEVAELKRKKKKLLREQRKQRERVELKMDLPGVSIADEGETGMFSLRTIRGHQLLEEVTQGDMSAADAFLSDLPRDDIYVSDGEDDDDASLGSDLDPEELAGVKEPQSLKDRKCVRFAEAEDDKEEEEENPLLVPLEEKAVLQEEQASLWFSKDGFSGIEDDADEALEISQAQLLFESRRKGQQPPPPPPSNEETKSKPPPCQGEAPKEVGAPKGSEVAPGPGEEERDGSSDSDSSSEDEESWKSQRGKKRGRGPKSEDDDGFEVVPIEDPVKHRILDPEGLALGALIASSKKAKRDLIDDSFSRYTFNEDEGELPDWFVQEEKQHRIRQLPVDKKEVEHYRKRWREINARPIKKVAEAKARKKRRMLKKLEQTKKKAEAVVNTVDISEREKVAQLRSLYRKAGLGKEKRQVTYVVAKKGVGRKVRRPAGVRGHFKVVDSRMKKDQRAQQRKEQKKKHKRK", "length": 836 }, "evidence": [ { "id": "Q9VXK5", "url": "https://omabrowser.org/oma/group/Q9VXK5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RSJ8-1", "protein_name": "pre-rRNA processing protein FTSJ3", "gene_name": "FTSJ3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGKKGKVGKSRRDKFYHLAKETGYRSRSAFKLIQLNRRFQFLQKARALLDLCAAPGGWLQVAAKFMPVSSLIVGVDLVPIKPLPNVVTLQEDITTERCRQALRKELKTWKVDVVLNDGAPNVGASWVHDAYSQAHLTLMALRLACDFLGRGGCFITKVFRSRDYQPLLWIFQQLFRRVQATKPQASRHESAEIFVVCQGFLAPDKVDSKFFDPKFAFKEVEIQAKTVTELVTKKKPKAEGYAEGDLTLYHRTSVTDFLRAANPVDFLSKASEIAIDDEELARHPATTEDVRACCQDIRVLGRKELRSLLNWRTKLRRHVAKKLKEQAKAMDISLSSGEEEEGEEEEQAARASQQPSKEEEEEEQLNRTLAEMKAQEVAELKRKKKKLLREQRKQRERVELKMDLPGVSIADEGETGMFSLRTIRGHQLLEEVTQGDMSAADTFLSDLPSDDIYISDAEEDDDDSASLDSDLDPEDLAGVREPQGLKDQKRVRLAEANDEKEEEGENPLLVPLEEKAVLQEEQASLWFSKDGFSGIEDDADEALEISQAQLLYESRRKGQQPLPAPSSVKTERKPPPCQGEAPEGAGAPSGTEAATGPGGEARDSSSDSDSSSSEDEDTWKPRSQKRRRGPEAGDDDGFEIVPIEDPARHRILDPEGLALGAIIASSKKAKRDLIDDSFSRYTFNEDEGELPEWFVQEEKQHRIRQLPLDKKEVEYYRKRWREINARPIKKVAEAKARKKRRMLKKLEQTKKKAEAVVNTVDISEREKVAQLRSLYKKAGLGKEKRQVTYVVAKKGVGRKVRRPAGVRGHFKVVDSRMKKDQRAQQRKEQKKKHKRK", "length": 836 }, "evidence": [ { "id": "Q9VXK5", "url": "https://omabrowser.org/oma/group/Q9VXK5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F4JTD2-1", "protein_name": "Putative rRNA methyltransferase", "gene_name": "TRM7B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGKVKGKHRLDKYYRLAKERGFRSRASYKLLQLDAKYSLLHSAHAVLDLCAAPGGWMQVAVEKVPVGSLVLGIDLVPILPVRGCVTMTQDITRTECKSKIKQVMEQHGVSAFNLVLHDGSPNVGGAWAQEAMSQNALVIDSVRLATEFLARNGNLVTKVFRSRDYNSVLYCLGRLFEKVEVFKPPASRSASAETYLVGLKYLAPAKIDPRLLDYRHLFKESAEPTRKVVDVLGGSKQKRNRDGYEDGESILRRVASAADFIWSENPLDVLGTTTSISFDDQASLPLKEHDLTTEEIKILCDDLPVLGKNDFKHILKWRMQIRKALTPEKKEVAKPEPDVGKEDEENEDDKLLNELEELTNTVDRKKKQAKKILAKRRAKDKARKATGPQMDVLEDGFVDNELFSLNAIKGKKDLMAVDNDEDDNGNAVDSENEDHGEGASDDSKDSDRDSDEERQKYTEQMEEIFEQAYERYMVKKEGSAKQRKRARQAHAEKLEEGDGDEEMKIDYDSDMNEEKDEANPLVVPLDDGVVQTKEEISNQWFSQNIFAEAVEEGDLGKDDSEDEIANKKKSKNLSKPDKSKQKASKASVLSDQSLPNSSKKEDEFEVVPAPATDSDSDSSSEDDVHTKAEILACAKKMLRKKQREQMLDDAYNKHMFVDEGLPKWFVDDEKQHRQPMKPVTKDEVNAMKAQFKEINARPAKKVAEAKARKKRAAQKRLEKVRKKANTISDTADISDRSKDKMIDKLYKKAAEPRKPRKELVVSKKGVGVKVGKGQKRVDRRMKSDDRKRGGGKPGRNGQKGTGKAGQKGKRPAGKPRGRKPG", "length": 821 }, "evidence": [ { "id": "Q9VXK5", "url": "https://omabrowser.org/oma/group/Q9VXK5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "G3HCU9-1", "protein_name": "pre-rRNA processing protein FTSJ3", "gene_name": "Ftsj3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGKKGKVGKSRRDKFYHLAKETGYRSRSAFKLIQLNRRFQFLQKARALLDLCAAPGGWLQVAAKFMPVSSLIVGVDLVPIKPLPNVVTLQEDITTERCRQALRKELKTWKVDVVLNDGAPNVGASWVHDAYSQANLTLMALRLACDFLARGGCFITKVFRSRDYQPLLWIFQQLFHRVQATKPQASRHESAEIFVVCQGFLAPDKVDSKFFDPKFAFKEVEVQAKTVTELVTKKKPKAEGYAEGDLTLYHRTSVTDFLRAANPVDFLSKASEISIDDEELAQHPATTEDIRACCQDIKVLGRKELRSLLNWRTKLRRYVAKKLKEQAKALDISLSSEEERDEDESIAETKQEDSEEEEEEQLNQTLAEMKAQEVAELKRKKKKLLREQRKQRERVELKMDLPGVSIADEGETGMFSLRTIRGQQLLEEVTQGDMNAADTFLSDLPTDDIYVSDAEEEDETSLESDLDSEELAGVRTHSSQKDRKCLQSAQVDDTKEEEGENPLLVPLEEKAVLQEEQANLWFSKDGFSGIEDDADEALEISQAKLLLKSRQKEPSTPPSSLKTEQKHPPCQNEVPKETEAVSGTEAVIDPRGEDKVNSSDSDSSSSSEDEESWKASRGIKRSRGSKADDDGFEVVPIEDPVKHRILDPEGLALGAVIASSKKAKRDLIDNSFNRYAFNEDEGELPEWFVQEEKQHRIRQLPIDKKEVEHYRKRWREINARPIKKVAEAKARKKRRMLKKLEQTKKKAEAVVNTVDISEREKVAQLRSLYKKAGLGKEKRQVTYVVAKKGVGRKVRRPAGVRGQFKVVDSRMKKDQRAQQRKEQKKKHKRK", "length": 830 }, "evidence": [ { "id": "Q9VXK5", "url": "https://omabrowser.org/oma/group/Q9VXK5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P25582-1", "protein_name": "27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase", "gene_name": "SPB1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MGKTQKKNSKGRLDRYYYLAKEKGYRARSSFKIIQINEKYGHFLEKSKVVIDLCAAPGSWCQVASKLCPVNSLIIGVDIVPMKPMPNVITFQSDITTEDCRSKLRGYMKTWKADTVLHDGAPNVGLGWVQDAFTQSQLTLQALKLAVENLVVNGTFVTKIFRSKDYNKLIWVFQQLFEKVEATKPPASRNVSAEIFVVCKGFKAPKRLDPRLLDPKEVFEELPDGQQNMESKIYNPEKKVRKRQGYEEGDNLLYHETSILDFVRTEDPISMLGEMNKFTIDENDHEWKILKKLKQTTDEFRSCIEDLKVLGKKDFKMILRWRKIAREILGIEVKDDAKTEIEVVPLTEEEQIEKDLQGLQEKQRLNVKRERRRKNEMKQKELQRMQMNMITPTDIGIEAASLGKESLFNLKTAEKTGILNDLAKGKKRMIFTDDELAKDNDIYIDENIMIKDKDSAADADDLESELNAMYSDYKTRRSERDAKFRAKQARGGDNEEEWTGFNEGSLEKKEEEGKDYIEDNDDEGVEGDSDDDEAITNLISKLKGQEGDHKLSSKARMIFNDPIFNNVEPDLPVNTVNDGIMSSESVGDISKLNKKRKHEEMHQKQDEADSSDESSSDDSDFEIVANDNASEEFDSDYDSEEEKNQTKKEKHSRDIDIATVEAMTLAHQLALGQKNKHDLVDEGFNRYTFRDTENLPDWFLEDEKEHSKINKPITKEAAMAIKEKIKAMNARPIKKVAEAKARKRMRAVARLEKIKKKAGLINDDSDKTEKDKAEEISRLMRKVTKKPKTKPKVTLVVASGRNKGLAGRPKGVKGKYKMVDGVMKNEQRALRRIAKKHHKKK", "length": 841 }, "evidence": [ { "id": "RGD:1307110", "url": "https://alliancegenome.org/gene/RGD:1307110#orthology", "database": "AGR" }, { "id": "MGI:1860295", "url": "https://alliancegenome.org/gene/MGI:1860295#orthology", "database": "AGR" }, { "id": "HGNC:17136", "url": "https://alliancegenome.org/gene/HGNC:17136#orthology", "database": "AGR" }, { "id": "FB:FBgn0030720", "url": "https://alliancegenome.org/gene/FB:FBgn0030720#orthology", "database": "AGR" }, { "id": "SGD:S000000559", "url": "https://alliancegenome.org/gene/SGD:S000000559#orthology", "database": "AGR" }, { "id": "Q9VXK5", "url": "https://omabrowser.org/oma/group/Q9VXK5/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54NX0-1", "protein_name": "pre-rRNA 2'-O-ribose RNA methyltransferase", "gene_name": "fsjC", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGQKKKKLAKGRLDKFYYMAKEQGYRSRAAFKLIQLNKKYNFLGTAKACLDLCAAPGGWMQVASKYMPVQSLIVGVDLVPIRQVRNCIGLTEDITTQKCRTEIKKALKTWKVDVCLHDGAPNMGTSWVQDAYQQAELTLHALKLATEFLTTGGWFVTKVFRGSDYNSLIWVFNKLFKKVESTKPPSSRNASAEIFVVCQGFLNPKRIDPKLLDPKFVFKEIQEVKKVDVLSEKKKVNRAGYEDGVTVLYKKGFISDFVNSNEHLQDLANFNAFEFDEAAKIFEQHELTTPEIKELVKDLKVLNKNDFQKIIKWKKAMAAYKEKLDNPDEEETEKPEEKKELTAEEMEENLQEEMKEYLALVEKKKRKEKKRQNELKRKHQRKIELTMHIPGDKIEETTDGDLYSMKGKDEFDEDIVADHSDISSDEFDSDDSDDDDDDDNNGDSKLIDDDEYLEQQLDEQYKLYQQRIRKKAAKLDDVKVKKDKIGQDGYNEDDEEFVEEQEESNPLLVGNKRKEPDAQAVSSLFFDNELFGGVEYRNPGDSESEPEQDGDDDQDDENNKPIDISKLKKQKPQAAQPITKKQKTTNSAEFGKQKSKYQKNPTLDDKDDQDDDDDKGNSIKGFEEVPVQEEVEYESDSDEDIDDKIKTKALGEFLIRKKSRQDLIDDSFNKYAFNDTGLPNWFTDDENRHNKAQTPLTKEMVDEIRRKIKEIDDRPIKKIAEAKARKKYRLGKKMEKTRDKASSIVDNPEMSNREKSKAIEKLYSGTDKKNMKPKKIIMIAKKSKTAGGGTGKYKIVDKRMKKDLRAQKNKLKTVGRSKDSSKKSKPSGGKNKK", "length": 833 }, "evidence": [ { "id": "Q9VXK5", "url": "https://omabrowser.org/oma/group/Q9VXK5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5RJT2-1", "protein_name": "pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3", "gene_name": "Ftsj3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGKKGKVGKSRRDKFYHLAKETGYRSRSAFKLIQLNRRFQFLQKARALLDLCAAPGGWLQVAAKFMPVSSLIVGVDLVPIKPLPNVVTLQEDITTERCRQALRKELKTWKVDVVLNDGAPNVGASWVHDAYSQAHLTLMALRLACDFLARGGCFITKVFRSRDYQPLLWIFQQLFHRVQATKPQASRHESAEIFVVCQGFLAPDKVDAKFFDPKFAFKEVEVQAKTVTELVTKKKPKAEGYAEGDLTLYHRTSVTDFLRAANPVDFLSKASEISIDDKELAQHPATTEDIRACCQDIKVLGRKELRSLLNWRTKLRRYVAKKLKEQAKALDISLSSEEEGDEEESAAETKQASEEEEEREEEEQLNRTLAEMKAQEVAELKRKKKKLLREQRKQRERVELKMDLPGVSIADEGETGMFSLRTIRGQQLLEEVTQGDMNAADTFLSDLPRDDIYVSDAEDDDDTSLESDLDPEELAGVRTHSDQKEQKSLQFAQVDDSKEEEGENPLLVPLEEKAVLQEEQASLWFSKDGFSGIDDDADEALEISQAQLLYKSRQKEQQPTDPPPPPTNLKTEKKSSQCQNEVPKETEAITDTGGEDRDSSDSDSSSSEDEDDWKVSRGKKRSRGSKADEDGFEVVPIEDPVKYRILDPEGLALGAVIASSKKAKRDLIDNSFNRYAFNEEEEELPEWFVQEEKQHRIRQLPLDKKEVEHYRKRWREINARPIKKVAEAKARKKRRMLKKLEQTKKKAEAVVNTVDISEREKVAQLRSLYKKAGLGKEKRQVTYVVAKKGVGRKVRRPAGVRGHFKVVDSRMKKDQRAQRKEQKRNHRRK", "length": 829 }, "evidence": [ { "id": "RGD:1307110", "url": "https://alliancegenome.org/gene/RGD:1307110#orthology", "database": "AGR" }, { "id": "MGI:1860295", "url": "https://alliancegenome.org/gene/MGI:1860295#orthology", "database": "AGR" }, { "id": "HGNC:17136", "url": "https://alliancegenome.org/gene/HGNC:17136#orthology", "database": "AGR" }, { "id": "FB:FBgn0030720", "url": "https://alliancegenome.org/gene/FB:FBgn0030720#orthology", "database": "AGR" }, { "id": "SGD:S000000559", "url": "https://alliancegenome.org/gene/SGD:S000000559#orthology", "database": "AGR" }, { "id": "Q9VXK5", "url": "https://omabrowser.org/oma/group/Q9VXK5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8IY81-1", "protein_name": "pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3", "gene_name": "FTSJ3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGKKGKVGKSRRDKFYHLAKETGYRSRSAFKLIQLNRRFQFLQKARALLDLCAAPGGWLQVAAKFMPVSSLIVGVDLVPIKPLPNVVTLQQDITTERCRQALRKELKTWKVDVVLNDGAPNVGASWVHDAYSQAHLTLMALRLACDFLARGGSFITKVFRSRDYQPLLWIFQQLFRRVQATKPQASRHESAEIFVVCQGFLAPDKVDSKFFDPKFAFKEVEVQAKTVTELVTKKKPKAEGYAEGDLTLYHRTSVTDFLRAANPVDFLSKASEIMVDDEELAQHPATTEDIRVCCQDIRVLGRKELRSLLNWRTKLRRYVAKKLKEQAKALDISLSSGEEDEGDEEDSTAGTTKQPSKEEEEEEEEEQLNQTLAEMKAQEVAELKRKKKKLLREQRKQRERVELKMDLPGVSIADEGETGMFSLSTIRGHQLLEEVTQGDMSAADTFLSDLPRDDIYVSDVEDDGDDTSLDSDLDPEELAGVRGHQGLRDQKRMRLTEVQDDKEEEEEENPLLVPLEEKAVLQEEQANLWFSKGSFAGIEDDADEALEISQAQLLFENRRKGRQQQQKQQLPQTPPSCLKTEIMSPLYQDEAPKGTEASSGTEAATGLEGEEKDGISDSDSSTSSEEEESWEPLRGKKRSRGPKSDDDGFEIVPIEDPAKHRILDPEGLALGAVIASSKKAKRDLIDNSFNRYTFNEDEGELPEWFVQEEKQHRIRQLPVGKKEVEHYRKRWREINARPIKKVAEAKARKKRRMLKRLEQTRKKAEAVVNTVDISEREKVAQLRSLYKKAGLGKEKRHVTYVVAKKGVGRKVRRPAGVRGHFKVVDSRMKKDQRAQQRKEQKKKHKRK", "length": 847 }, "evidence": [ { "id": "RGD:1307110", "url": "https://alliancegenome.org/gene/RGD:1307110#orthology", "database": "AGR" }, { "id": "MGI:1860295", "url": "https://alliancegenome.org/gene/MGI:1860295#orthology", "database": "AGR" }, { "id": "HGNC:17136", "url": "https://alliancegenome.org/gene/HGNC:17136#orthology", "database": "AGR" }, { "id": "FB:FBgn0030720", "url": "https://alliancegenome.org/gene/FB:FBgn0030720#orthology", "database": "AGR" }, { "id": "SGD:S000000559", "url": "https://alliancegenome.org/gene/SGD:S000000559#orthology", "database": "AGR" }, { "id": "Q9VXK5", "url": "https://omabrowser.org/oma/group/Q9VXK5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DBE9-1", "protein_name": "pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3", "gene_name": "Ftsj3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGKKGKVGKSRRDKFYHLAKETGYRSRSAFKLIQLNRRFQFLQKARALLDLCAAPGGWLQVAAKFMPVSSLIVGVDLVPIKPLPNVVTLQEDITTERCRQALRKELKTWKVDVVLNDGAPNVGASWVHDAYSQAHLTLMALRLACDFLARGGCFITKVFRSRDYQPLLWIFQQLFHRVQATKPQASRHESAEIFVVCQGFLAPDKVDAKFFDPKFAFKEVEVQAKTVTELVTKKKPKAEGYAEGDLTLYHRTSVTDFLRAANPVDFLSKASEISIDDEELAQHPATTEDIRVCCQDIKVLGRKELRSLLNWRTKLRRYVAKKLKEQAKALDISLSSEEEEEGDEEEAVAETKQAPEEEEEREEEQLNRTLAEMKAQEVAELKRKKKKLLREQRKQRERVELKMDLPGVSIADEGETGMFSLRTIRGQQLLEEVTQGDMNAADTFLSDLPRDDIYVSDAEDDDDTSLESDLDPEELAGVRTHSDLKEQKYLRFTQVDDNKEEEGENPLLVPLEEKAVLQEEQASLWFSKDGFSGIEDDADEALEISQAQLLYKSRQKEQQPTDPPPPPTNLKTEKKSPQGQNEVPKETEAILGTEAVTDPGGEERGNSSDSDSSSSEDEDSWKVSRGVKRGRGSKADEDGFEVVPIQDPVKYRILDPEGLALGAVIASSKKAKRDLIDNSFNRYAFNEEEGELPEWFAQEEKQHRIRQLPVDKKEVEHYRKRWREINARPIKKVAEAKARKKRRVLKKLEQTKKKAEAVVNTVDISEREKVAQLRSLYKKAGLGKEKRQVTYVVAKKGVGRKVRRPAGVKGHFKVVDSRMKKDQRAQQRKEQKKKHKRK", "length": 838 }, "evidence": [ { "id": "RGD:1307110", "url": "https://alliancegenome.org/gene/RGD:1307110#orthology", "database": "AGR" }, { "id": "MGI:1860295", "url": "https://alliancegenome.org/gene/MGI:1860295#orthology", "database": "AGR" }, { "id": "HGNC:17136", "url": "https://alliancegenome.org/gene/HGNC:17136#orthology", "database": "AGR" }, { "id": "FB:FBgn0030720", "url": "https://alliancegenome.org/gene/FB:FBgn0030720#orthology", "database": "AGR" }, { "id": "SGD:S000000559", "url": "https://alliancegenome.org/gene/SGD:S000000559#orthology", "database": "AGR" }, { "id": "Q9VXK5", "url": "https://omabrowser.org/oma/group/Q9VXK5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "rRNA (guanine) methyltransferase activity", "id": "GO:0016435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016435", "evidence": [ { "database": "UniProtKB", "id": "Q9VXK5", "url": "https://www.uniprot.org/uniprotkb/Q9VXK5" } ], "pmid": "" }, { "name": "rRNA (uridine-2'-O-)-methyltransferase activity", "id": "GO:0008650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008650", "evidence": [ { "database": "UniProtKB", "id": "Q9VXK5", "url": "https://www.uniprot.org/uniprotkb/Q9VXK5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "rRNA methylation", "id": "GO:0031167", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031167", "evidence": [ { "database": "UniProtKB", "id": "Q9VXK5", "url": "https://www.uniprot.org/uniprotkb/Q9VXK5" } ], "pmid": "" }, { "name": "maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000463", "evidence": [ { "database": "UniProtKB", "id": "Q9VXK5", "url": "https://www.uniprot.org/uniprotkb/Q9VXK5" } ], "pmid": "" }, { "name": "maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000466", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000466", "evidence": [ { "database": "UniProtKB", "id": "Q9VXK5", "url": "https://www.uniprot.org/uniprotkb/Q9VXK5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q9VXK5", "url": "https://www.uniprot.org/uniprotkb/Q9VXK5" } ], "pmid": "" }, { "name": "preribosome, large subunit precursor", "id": "GO:0030687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030687", "evidence": [ { "database": "UniProtKB", "id": "Q9VXK5", "url": "https://www.uniprot.org/uniprotkb/Q9VXK5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "48628", "name": "", "equation": "a ribonucleotide in rRNA + S-adenosyl-L-methionine = a 2'-O-methylribonucleotide in rRNA + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VXK5-1" ], "evidence": [ { "id": "48628", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/48628" } ] }, { "id": "R-DME-6791221", "name": "30S pre-rRNA is nucleolytically processed at site 1 to yield 21S pre-rRNA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O46072-1", "Q9W4J5-1", "Q9VIF6-1", "Q07886-1", "Q9W1V3-1", "Q9VVK8-1", "Q9VXK5-1" ], "evidence": [ { "id": "R-DME-6791221", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6791221" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "O46072", "gene_name": "kz", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "O46072", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O46072" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "O46072", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O46072" } ] } ] }, { "uniprot_ac": "Q07886", "gene_name": "Dbp45A", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q07886", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07886" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q07886", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07886" } ] } ] }, { "uniprot_ac": "Q9VIF6", "gene_name": "pths", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q9VIF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VIF6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q9VIF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VIF6" } ] } ] }, { "uniprot_ac": "Q9VVK8", "gene_name": "ais", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q9VVK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVK8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q9VVK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVK8" } ] } ] }, { "uniprot_ac": "Q9VXK5", "gene_name": "dSpb1", "activity": [ { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "Q9VXK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXK5" } ] } ] }, { "uniprot_ac": "Q9W1V3", "gene_name": "Fib", "activity": [ { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "Q9W1V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W1V3" } ] } ] }, { "uniprot_ac": "Q9W4J5", "gene_name": "", "activity": [ { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "Q9W4J5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W4J5" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VXK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXK5" }, { "id": "PF11861", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11861" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUF3381", "eco_id": "ECO_0000259", "start_pos": 235, "end_pos": 387, "start_aa": "Lys", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q9VXK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXK5" }, { "id": "PF01728", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01728" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ribosomal RNA methyltransferase FtsJ", "eco_id": "ECO_0000259", "start_pos": 25, "end_pos": 200, "start_aa": "Arg", "end_aa": "Tyr", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q9VXK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXK5" }, { "id": "PF07780", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07780" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ribosomal RNA methyltransferase SPB1-like C-terminal", "eco_id": "ECO_0000259", "start_pos": 599, "end_pos": 802, "start_aa": "Ser", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VXN3-1", "uniprot_ac": "Q9VXN3", "uniprot_id": "Q9VXN3_DROME", "mass": { "chemical_mass": 45402.0, "monoisotopic_mass": 45402.0 }, "refseq": { "ac": "NP_001285302", "name": "uncharacterized protein, isoform B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285302" }, "gene_names": [ { "name": "Dmel\\CG8578", "type": "recommended", "evidence": [ { "id": "Q9VXN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXN3" } ] }, { "name": "CG8578", "type": "synonym", "evidence": [ { "id": "NP_001285302", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285302" }, { "id": "Q9VXN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXN3" } ] }, { "name": "Dmel\\CG8578", "type": "synonym", "evidence": [ { "id": "NP_001285302", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285302" } ] }, { "name": "Dmel_CG8578", "type": "synonym", "evidence": [ { "id": "Q9VXN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXN3" } ] } ], "protein_names": [ { "name": "Leucine-rich repeat flightless-interacting protein 2", "type": "recommended", "evidence": [ { "id": "Q9VXN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXN3/entry#names_and_taxonomy" } ] }, { "name": "CG8578-PB", "type": "synonym", "evidence": [ { "id": "NP_001285302", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285302" } ] }, { "name": "uncharacterized protein, isoform B", "type": "synonym", "evidence": [ { "id": "NP_001285302", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285302" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VXN3", "url": "https://www.uniprot.org/uniprotkb/Q9VXN3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG8578", "url": "https://www.uniprot.org/uniprotkb/Q9VXN3", "locus": { "chromosome": "X", "start_pos": 15847858, "end_pos": 15844476, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0030699", "url": "https://www.ensemblgenomes.org/id/FBgn0030699" } ] } } ], "crossref": [ { "id": "FB:FBgn0030699", "url": "https://alliancegenome.org/gene/FB:FBgn0030699", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0030699", "url": "https://bgee.org/?page=gene&gene_id=FBgn0030699", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0030699", "url": "https://flybase.org/reports/FBgn0030699", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "32540", "url": "https://www.ncbi.nlm.nih.gov/gene/32540", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019139", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019139", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG8578", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG8578", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RDKCREH", "url": "https://omabrowser.org/oma/group/RDKCREH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VXN3", "url": "https://www.orthodb.org/?gene=Q9VXN3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19212", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19212", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19212:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19212:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09738", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09738", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q9VXN3", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q9VXN3", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001285302", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285302", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VXN3", "url": "https://www.uniprot.org/uniprotkb/Q9VXN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VXN3-1", "url": "https://www.uniprot.org/uniprotkb/Q9VXN3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESISTTGRRRNNMRINAEDNALDQITKEAEARLAARRQARAEAREIRMRELERQQKEQEITADRVFDMQNSTAVGSETLSAHPVRLAYGGLLNVTRASASRRSSEDSVEEEGRSFRDFKHELKDVEERFRKAMITNAQLDNDRASQAYEVKLLKDKCEIMEESYAQLQREFKEKMRDCNALKRNLDRANLELKLVQGQLNERDSLIAEQGLLIVAVENADGSDAKRALVSVENAKVLASVQGSLDVRLKKFSDEKQRLLAEVQKLHEQLDEYKSDGISGRRSLSQGSFGDENDYEAQRETNKIISDHKYKLQKAEQEIANLQSSLARSETQVIRYKSTAEAAEKAEAELKLERRKLQREHRELLEKLEEAETSNNHLLKRLDKLKNAKSAILKDL", "length": 396, "header": "tr|Q9VXN3-1|Q9VXN3_DROME Isoform 1 of Leucine-rich repeat flightless-interacting protein 2 OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG8578 PE=1 SV=2 CANONICAL=Q9VXN3-1" }, "isoforms": [ { "isoform_ac": "Q9VXN3-1", "url": "https://www.uniprot.org/uniprotkb/Q9VXN3/entry#Q9VXN3-1", "sequence": { "sequence": "MESISTTGRRRNNMRINAEDNALDQITKEAEARLAARRQARAEAREIRMRELERQQKEQEITADRVFDMQNSTAVGSETLSAHPVRLAYGGLLNVTRASASRRSSEDSVEEEGRSFRDFKHELKDVEERFRKAMITNAQLDNDRASQAYEVKLLKDKCEIMEESYAQLQREFKEKMRDCNALKRNLDRANLELKLVQGQLNERDSLIAEQGLLIVAVENADGSDAKRALVSVENAKVLASVQGSLDVRLKKFSDEKQRLLAEVQKLHEQLDEYKSDGISGRRSLSQGSFGDENDYEAQRETNKIISDHKYKLQKAEQEIANLQSSLARSETQVIRYKSTAEAAEKAEAELKLERRKLQREHRELLEKLEEAETSNNHLLKRLDKLKNAKSAILKDL", "length": 396, "header": "tr|Q9VXN3-1|Q9VXN3_DROME Isoform 1 of Leucine-rich repeat flightless-interacting protein 2 OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG8578 PE=1 SV=2 CANONICAL=Q9VXN3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VXN3", "url": "https://www.uniprot.org/uniprotkb/Q9VXN3" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VXN3", "url": "https://www.uniprot.org/uniprotkb/Q9VXN3" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXN3", "url": "https://www.uniprot.org/uniprotkb/Q9VXN3" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXN3", "url": "https://www.uniprot.org/uniprotkb/Q9VXN3" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VXN3", "url": "https://www.uniprot.org/uniprotkb/Q9VXN3" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VXN3", "url": "https://www.uniprot.org/uniprotkb/Q9VXN3" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VXN3", "url": "https://www.uniprot.org/uniprotkb/Q9VXN3" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXN3", "url": "https://www.uniprot.org/uniprotkb/Q9VXN3" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXN3", "url": "https://www.uniprot.org/uniprotkb/Q9VXN3" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VXN3", "url": "https://www.uniprot.org/uniprotkb/Q9VXN3" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VXN3", "url": "https://www.uniprot.org/uniprotkb/Q9VXN3" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG8578", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG8578", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M2BF37-1", "protein_name": "Leucine-rich repeat flightless-interacting protein 1 isoform X1", "gene_name": "lrrfip1a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGSQGPGRKRTPSKNGLTAEEDALNVIAKEAEARLAAKRAARAEAREIRMKELERQQKEVSDDEERMSVGSRSNVRADDRLERDYLEKGSSRASTISGATLTSLGGTSSRRGSGDTSISADTEASIREIKDSLLEVEEKYRKAMVSNAQLDNEKTNMMYEVDTLRDSLMELEEMLFETRRELEEKIKDLEREKHAHSILQFQFSELKETLKQSEELLSKHGIVLGPDLVTNGETGDEVGNADPNSQTASAEIREGSSVLGIHQLKHKDQEQKYLDDEVQGNQQSSNALFSSTNPPLEANDNGVLGDSVVPGVEQHENRTEEPLSSVGNKEVTATEPNEEVKSEEHELENSKDNAVELERKVCMGEHLETEQQESKCVNSSQEIKEEAPLDSVSNTMHDETDKPDEAVLDEQCKEEPVESSQMEEPPKTQVTSASNKKKKKKKKNKQKQKQSDKQESGTAMEVLNEDNSNQIVESVLEGTNEEPLANAVSETTMNADLPASSCSDITTKGQDCIEVAATNTNVDDDQDGVQLVTDEADSAENSKTISNFDCSESSNDILSEGPSNNIISNTTDDPSNNIICNTADDLSNNIISDTADDLSNNIISDTADDLSNNIISDTADDLSNDIITNTSVDLSSDIITNTPDDLSNDSITNTADDPSNNIISDPATIIEERAEDSANSSLEPAITCSELKSSEMEASCHEPSVGPITSENNKTLLVDAKEEKVDLECDEEPSAQNVDVDRICDPEDQEASAQFDFHVMENVENKAELMMQEQTVDPLMDSQLQDSVQSEVGKEKEQGELDKENLKAHKEEVFAGSKVDYSPFIETQVHQCSPLFTNEANQESVEPSDQNSMVEKVEEEISIQGLVTPDGQLPKDHNDLLIELDVVGLVHKQEDAVEEDEGESFDFDETDLEASSDGPLKKSLDKPKEEVTLLKENVQEASQENQSNVIDEDLTQEDEHLQLADQESKPHEQKDDGHDTENMQSRDVEGCLTEQSLINCDVSPLSQQHNTSANKEDTFEEHQKESVDVPVSERVNLISDKEKREVGQEISSSIPHKKQASVISGDPKLEKEITGNNKEDESREYRKSAKGKGKGKGKEDCKMS", "length": 1104 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-030131-99", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-99#orthology", "database": "AGR" }, { "id": "HGNC:6702", "url": "https://alliancegenome.org/gene/HGNC:6702#orthology", "database": "AGR" }, { "id": "RGD:1359548", "url": "https://alliancegenome.org/gene/RGD:1359548#orthology", "database": "AGR" }, { "id": "MGI:1342770", "url": "https://alliancegenome.org/gene/MGI:1342770#orthology", "database": "AGR" }, { "id": "FB:FBgn0030699", "url": "https://alliancegenome.org/gene/FB:FBgn0030699#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M2BGK9-1", "protein_name": "Leucine-rich repeat flightless-interacting protein 2 isoform X1", "gene_name": "lrrfip1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASQVTGRKRIPNREKLSAEDDALIQIAREAEARLAAKRAARAEAREIRMKELERQQKEIYHAQKKYYGLDSKWGHIEQWMEDSERYSRHTRRHTSISDDEERMSVGSRGSLRGNHADLCSSTSSLTSARLQNGRPSALFIETPRSRSHRGSLHEESSYSATRRFSGSSARGPSDYNGFLGSSSRASSRASSARASPVVEERSDFLEKGSRTASTLSAATLASLGGGLSRRGSCDTSISADTEASIREMKDSLVEVEEKYRKAMVSIAQLDNEKTNMMYQVDTLRDTLMELEELLCETQREREEKTRECERERHAHNVLKFQFEEMKETLKQSEELLTEAQQSRGKHADYIREISDLQETLEWKDKKILALERQKEYSDIIHDERETLRDEVCRLRDALKKNGIVMGSEVTANGKVEDGAIDRHVNAETASRLNQDLSSGDSMLEIRLRKLMEERESLLDQVRKLKASAEQKQKNGTEETGSADEDDLQNGLDPHILDLQRDANRQISDLKFKLVKSEQEVTALEQNIIRLEGQVSRYKTSAEAAEKVEDELKVEKRKLQRELRSALDRIDELEASNSHLTKRLEKMKANRSALLAQQ", "length": 598 }, "evidence": [ { "id": "HGNC:6702", "url": "https://alliancegenome.org/gene/HGNC:6702#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050208-324", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-324#orthology", "database": "AGR" }, { "id": "RGD:1306234", "url": "https://alliancegenome.org/gene/RGD:1306234#orthology", "database": "AGR" }, { "id": "MGI:1342770", "url": "https://alliancegenome.org/gene/MGI:1342770#orthology", "database": "AGR" }, { "id": "MGI:1918518", "url": "https://alliancegenome.org/gene/MGI:1918518#orthology", "database": "AGR" }, { "id": "FB:FBgn0030699", "url": "https://alliancegenome.org/gene/FB:FBgn0030699#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M2BGT5-1", "protein_name": "Leucine-rich repeat flightless-interacting protein 2", "gene_name": "lrrfip2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGTPGSGRKRAPVKDRFSAEDEALSSIAREAEARLAAKRAARAEAREIRMKELERQQKELSYHQHSSSSRKWGQIHQWMADAEKARHGHHSSSHSRRGLNDDTASVRSVGSYRSNSSSLRDLSSSHRSSRGNSSRRRDVVSGVSSSSSLKSSLSTSSVYNDLHKKSVGSSSKKDLLTGLYHDQRNYTSLKNSKPPPSTASTYTPRAPSSSSSAGLTRSYSVASICDDGLYGSYSSKAPSECSWYSSGASSTRSSPVSSSDDDSASTVSQSRRGRRDSVMSDFSDISETTADYFSRSNRRGSVVSDLDDLSIPDLDSLDEKSDKQFTDYSRPSSRCATPALSAAALASLGGSSSRRGSGDAGSVIMDSEASISELRDIYDLKDQIQDVEGRYMQGLKELKESLSEVEEKYKKAMVSNAQLDNEKANLIYQVDTLKDVIEEMEEQMSELRRETEDKSKELERQKHTCTVLQHKQEELKEGIRQRDELIEENQKIQQKLDTLTREVFDLQETVNWKDKKIGALERQKEYFDCIRIERDELRDELADLKGKSRMGEKHGLVIIPEDTPNGDVNHESPTSGITVVTQEAAQVLESAGDGPLDVRLRKLADEKDELLSQIRKLKMQLEEERQKHAKIDSVYTEGERMENGTDLHFIEMQRDTNRQISEYKFKLSKAEQEMATMEQNVNRLEGQVSRYKASADNAEKIEDELKAEKRKLQRELRTALDKIEEMEMTNNHLVKRLEKMKANRNALLSQQ", "length": 751 }, "evidence": [ { "id": "HGNC:6703", "url": "https://alliancegenome.org/gene/HGNC:6703#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-7781", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-7781#orthology", "database": "AGR" }, { "id": "RGD:1306234", "url": "https://alliancegenome.org/gene/RGD:1306234#orthology", "database": "AGR" }, { "id": "MGI:1918518", "url": "https://alliancegenome.org/gene/MGI:1918518#orthology", "database": "AGR" }, { "id": "FB:FBgn0030699", "url": "https://alliancegenome.org/gene/FB:FBgn0030699#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q32MZ4-1", "protein_name": "Leucine-rich repeat flightless-interacting protein 1", "gene_name": "LRRFIP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRRSRRNTSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKELNELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFNPESREDTRGGNEKGKSKEDCTMS", "length": 808 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-030131-99", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-99#orthology", "database": "AGR" }, { "id": "HGNC:6702", "url": "https://alliancegenome.org/gene/HGNC:6702#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050208-324", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-324#orthology", "database": "AGR" }, { "id": "RGD:1359548", "url": "https://alliancegenome.org/gene/RGD:1359548#orthology", "database": "AGR" }, { "id": "MGI:1342770", "url": "https://alliancegenome.org/gene/MGI:1342770#orthology", "database": "AGR" }, { "id": "FB:FBgn0030699", "url": "https://alliancegenome.org/gene/FB:FBgn0030699#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3UZ39-1", "protein_name": "Leucine-rich repeat flightless-interacting protein 1", "gene_name": "Lrrfip1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSPEGAQNKEIDCLSPEAQRLAEARLAAKRAARAEAREIRMKELERQQKEVEERPDKDFAEKGSRNMPSLSAATLASLGGTSSRRGSGDTSISMDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESQRQYEEKNKEFEREKHAHSILQFQFAEVKEALRQREEMLEKHGIILNSEIATNGETSDTVNDVGYQAPTKITKEELNALKSAGEGTLGKAKEVEVKKEIVEKVGQRETLQNSEQEQPKPNTGKDCVDRGVSHPGEKAENQRPAEDSALSPGPLAGAKCEQQVQSQDQENTSDLKNSEQIESHKVTNKSDSRASNSPEQSSCLEGLDSEVPGPTEDLKTDLGKGSFEPCPDYILGQTAEIDKVTCTDSRGTGGNQREDEVQAGDTTVEDQVGTVASGPAKQSKGTENHGESCLKDGLGQSSERELTQEVAEPEEAIVQIPQAGGENTITKADDAEGRDEKPIQAEAQASPGAPINQSGHQDTTGPGSTDAQRTPPHAKERKKQGKSEQQAEALDSPQKKTKNKKKKNKKKKAATPAETCRDANEELNCQDPDVGDMEEEERLQVTDKKQASGSPEQKIRAGSREPVEDPQSGSSGKQNKVEEDGPTEGPTDILDQNSPQCEDREISPVGEKGPQCDTSQIGSEEGHVTSQHGGQAVENHNLDNSDLSGQLEGFNSESGGQAREEVGNSKSKEDCTMS", "length": 729 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-030131-99", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-99#orthology", "database": "AGR" }, { "id": "HGNC:6702", "url": "https://alliancegenome.org/gene/HGNC:6702#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050208-324", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-324#orthology", "database": "AGR" }, { "id": "RGD:1359548", "url": "https://alliancegenome.org/gene/RGD:1359548#orthology", "database": "AGR" }, { "id": "MGI:1342770", "url": "https://alliancegenome.org/gene/MGI:1342770#orthology", "database": "AGR" }, { "id": "FB:FBgn0030699", "url": "https://alliancegenome.org/gene/FB:FBgn0030699#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q4V7E8-1", "protein_name": "Leucine-rich repeat flightless-interacting protein 2", "gene_name": "Lrrfip2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGTPGSGRKRTPVKDRFSAEDEALSNIAREAEARLAAKRAARAEARDIRMRELERQQRESSSKDITGTHWSRASTPKRRDMMYDSIKDRSSRVSSLLDEKSDKQYAENYTRPSSRNSASATTPLSGNSSRRGSGDTSSLIDPDTSLSELRESLSEVEEKYKKAMVSNAQLDNEKNNLIYQVDTLKDVIEEQEEQMAEFYRENEEKSKELERQKHMCSVLQHKMDELKEGLRQRDELIEKHGLVIIPESTPNGDVNHEPVVGAITAVSQEAAQVLESAGEGPLDVRLRKLAEEKDELLSQIRKLKLQLEEERQKCSRNDGMSGDLAGLQNGSDLQFIEMQRDANRQISEYKFKLSKAEQDIATLEQSISRLEGQVLRYKTAAENAEKIEDELKAEKRKLQRELRTAQDKIEEMEMTNSHLAKRLEKMKANRTALLAQQ", "length": 437 }, "evidence": [ { "id": "HGNC:6703", "url": "https://alliancegenome.org/gene/HGNC:6703#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-7781", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-7781#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050208-324", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-324#orthology", "database": "AGR" }, { "id": "RGD:1306234", "url": "https://alliancegenome.org/gene/RGD:1306234#orthology", "database": "AGR" }, { "id": "MGI:1918518", "url": "https://alliancegenome.org/gene/MGI:1918518#orthology", "database": "AGR" }, { "id": "FB:FBgn0030699", "url": "https://alliancegenome.org/gene/FB:FBgn0030699#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q66HF9-1", "protein_name": "Leucine-rich repeat flightless-interacting protein 1", "gene_name": "Lrrfip1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTSPEGAQNKEIDCLSPEAQRLAEARLAAKRAARAEAREIRMKELERQQKEVEERPDKDFAEKGSRNMPSLSAATLASLGGTSSRRGSGDTSISMDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESQRQYEEKNKEFEREKHAHSILQFQFAEVKEALRQREEMLEKHGIILNSEIATNGETSDTVNDVGYQAPTKITKEELNALKAAGEGTLGKAKEVEVKKEIVEKVGQRETLQDSEQEQPKLNTGKDCVDRGVLHPGEKAENQRPVEDSALSPGPLAGAKCEQEVQSQDQENTSILKSPEQIESHEVTNKSDSRDSNSPEPSSCRGGLDSEVSGPTALGIKNQSENSMDSQGKENQEDLGKGSFEPRPDHVLGQTPEIDKVSCTDSRGTGGNHLEDVVQAGDTIVEDQVGTMASAEQSKSMENHIGRSLNDGLGQSSERELAHEAAELEEALTQSSQAGGENTVTEAEDAAVRDEKPLQADVQATPAAPTVQSGHQDTTGPGSTDTKHTSPHAKERNKAKSEQQAEALDSPQKKTKNKKKKNKKKKAAAPMETCKDANEESSCQDPDVGDGEEEERVQATDKKWAAETPELKEDPQSRPSGKQNDAEEDSGPAEGPTDVLDQNSLQCADGDISPVGRKGPQRDASQIGGEEGLVPSQHPGQADEKGIEGHSVDNSDLSGELGGFNSESGEQAREEVGNSKSKEDCTMS", "length": 738 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-030131-99", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-99#orthology", "database": "AGR" }, { "id": "HGNC:6702", "url": "https://alliancegenome.org/gene/HGNC:6702#orthology", "database": "AGR" }, { "id": "RGD:1359548", "url": "https://alliancegenome.org/gene/RGD:1359548#orthology", "database": "AGR" }, { "id": "MGI:1342770", "url": "https://alliancegenome.org/gene/MGI:1342770#orthology", "database": "AGR" }, { "id": "FB:FBgn0030699", "url": "https://alliancegenome.org/gene/FB:FBgn0030699#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q91WK0-1", "protein_name": "Leucine-rich repeat flightless-interacting protein 2", "gene_name": "Lrrfip2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGTPGSGRKRTPVKDRFSAEDEALSNIAREAEARLAAKRAARAEARDIRMRELERQQREGVEDTLSLRSLGSHRLDEKSDKQYAENYTRPSSRNSASATTPLSGQSSRRGSGDTSSLIDPDTSLSELRESLSEVEEKYKKAMVSNAQLDNEKNNLIYQVDTLKDVIEEQEEQMAEFYRENEEKSKELERQKHMCSVLQHKMDELKEGLRQRDELIEKHGLVIIPDSTPNGDVHHEPVVGAITAVSQEAAQVLESAGEGPLDVRLRKLAGEKDELLSQIRKLKLQLEEERQKCSRNDGMSGDLAGLQNGSDLQFIEMQRDANRQISEYKFKLSKAEQDIATLEQSISRLEGQVLRYKTAAENAEKIEDELKAERRKLQRELRTAQDKIEEMEMTNSHLAKRLEKMKANRTALLAQQ", "length": 415 }, "evidence": [ { "id": "HGNC:6703", "url": "https://alliancegenome.org/gene/HGNC:6703#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-7781", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-7781#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050208-324", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-324#orthology", "database": "AGR" }, { "id": "RGD:1306234", "url": "https://alliancegenome.org/gene/RGD:1306234#orthology", "database": "AGR" }, { "id": "MGI:1918518", "url": "https://alliancegenome.org/gene/MGI:1918518#orthology", "database": "AGR" }, { "id": "FB:FBgn0030699", "url": "https://alliancegenome.org/gene/FB:FBgn0030699#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y608-1", "protein_name": "Leucine-rich repeat flightless-interacting protein 2", "gene_name": "LRRFIP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGTPASGRKRTPVKDRFSAEDEALSNIAREAEARLAAKRAARAEARDIRMRELERQQKEYSLHSFDRKWGQIQKWLEDSERARYSHRSSHHRPYLGVEDALSIRSVGSHRYDMFKDRSSRLSSLNHSYSHSHGMKKRSSDSHKDLLSGLYFDQRNYSSLRHSKPTSAYYTRQSSSLYSDPLATYKSDRASPTANSGLLRSASLASLYNGGLYNPYGPRTPSECSYYSSRISSARSSPGFTNDDTASIVSSDRASRGRRESVVSAADYFSRSNRRGSVVSEVDDISIPDLSSLDEKSDKQYAENYTRPSSRNSASATTPLSGNSSRRGSGDTSSLIDPDTSLSELRDIYDLKDQIQDVEGRYMQGLKELKESLSEVEEKYKKAMVSNAQLDNEKNNLIYQVDTLKDVIEEQEEQMAEFYRENEEKSKELERQKHMCSVLQHKMEELKEGLRQRDELIEEKQRMQQKIDTMTKEVFDLQETLLWKDKKIGALEKQKEYIACLRNERDMLREELADLQETVKTGEKHGLVIIPDGTPNGDVSHEPVAGAITVVSQEAAQVLESAGEGPLDVRLRKLAGEKEELLSQIRKLKLQLEEERQKCSRNDGTVGDLAGLQNGSDLQFIEMQRDANRQISEYKFKLSKAEQDITTLEQSISRLEGQVLRYKTAAENAEKVEDELKAEKRKLQRELRTALDKIEEMEMTNSHLAKRLEKMKANRTALLAQQ", "length": 721 }, "evidence": [ { "id": "HGNC:6703", "url": "https://alliancegenome.org/gene/HGNC:6703#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-7781", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-7781#orthology", "database": "AGR" }, { "id": "RGD:1306234", "url": "https://alliancegenome.org/gene/RGD:1306234#orthology", "database": "AGR" }, { "id": "MGI:1918518", "url": "https://alliancegenome.org/gene/MGI:1918518#orthology", "database": "AGR" }, { "id": "FB:FBgn0030699", "url": "https://alliancegenome.org/gene/FB:FBgn0030699#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "Q9VXN3", "url": "https://www.uniprot.org/uniprotkb/Q9VXN3" } ], "pmid": "" }, { "name": "adult somatic muscle development", "id": "GO:0007527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007527", "evidence": [ { "database": "UniProtKB", "id": "Q9VXN3", "url": "https://www.uniprot.org/uniprotkb/Q9VXN3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "Q9VXN3", "url": "https://www.uniprot.org/uniprotkb/Q9VXN3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 71, "end_pos": 73, "annotation": "n_glycosylation_sequon" }, { "start_pos": 94, "end_pos": 96, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 71, "end_pos": 73 }, { "start_pos": 94, "end_pos": 96 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VXN8-1", "uniprot_ac": "Q9VXN8", "uniprot_id": "Q9VXN8_DROME", "mass": { "chemical_mass": 49950.0, "monoisotopic_mass": 49950.0 }, "refseq": { "ac": "NP_573079", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573079" }, "gene_names": [ { "name": "Dmel\\CG8509", "type": "recommended", "evidence": [ { "id": "Q9VXN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXN8" } ] }, { "name": "CG8509", "type": "synonym", "evidence": [ { "id": "NP_573079", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573079" }, { "id": "Q9VXN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXN8" } ] }, { "name": "Dmel\\CG8509", "type": "synonym", "evidence": [ { "id": "NP_573079", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573079" } ] }, { "name": "Dmel_CG8509", "type": "synonym", "evidence": [ { "id": "Q9VXN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXN8" } ] } ], "protein_names": [ { "name": "Serine/threonine-protein phosphatase 2A activator", "type": "recommended", "evidence": [ { "id": "Q9VXN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXN8/entry#names_and_taxonomy" } ] }, { "name": "5.2.1.8", "type": "synonym", "evidence": [ { "id": "Q9VXN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXN8/entry#names_and_taxonomy" } ] }, { "name": "CG8509-PA", "type": "synonym", "evidence": [ { "id": "NP_573079", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573079" } ] }, { "name": "Phosphotyrosyl phosphatase activator", "type": "synonym", "evidence": [ { "id": "Q9VXN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXN8/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_573079", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573079" } ] } ], "function": [ { "annotation": "PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.", "evidence": [ { "database": "UniProtKB", "id": "Q9VXN8", "url": "https://www.uniprot.org/uniprotkb/Q9VXN8#function" }, { "database": "UniProtKB", "id": "RU361210", "url": "https://www.uniprot.org/uniprotkb/RU361210#function" } ] } ], "disease": [ { "disease_id": "DOID:0070486", "recommended_name": { "id": "DOID:0070486", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070486", "name": "Parkinson's disease 25", "description": "An early-onset Parkinson's disease characterized by mild to moderately impaired intellectual development that has_material_basis_in homozygous or compound heterozygous mutation in the PTPA gene on chromosome 9q34.11." }, "synonyms": [ { "id": "DOID:0070486", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070486", "name": "autosomal recessive early-onset Parkinson disease 25 with impaired intellectual development", "description": "" }, { "id": "DOID:0070486", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070486", "name": "PARK25", "description": "" }, { "id": "MONDO:0957576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0957576", "name": "Parkinson disease 25, autosomal recessive early-onset, with impaired intellectual development", "description": "" }, { "id": "MIM:620482", "resource": "MIM", "url": "https://www.omim.org/entry/620482", "name": "Parkinson disease 25, autosomal recessive early-onset, with impaired intellectual development", "description": "Parkinson disease 25, autosomal recessive early-onset, with impaired intellectual development" } ], "unlinked_id_list": [], "evidence": [ { "id": "0070486", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070486" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VXN8", "url": "https://www.uniprot.org/uniprotkb/Q9VXN8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG8509", "url": "https://www.uniprot.org/uniprotkb/Q9VXN8", "locus": { "chromosome": "X", "start_pos": 15810947, "end_pos": 15809555, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0030696", "url": "https://www.ensemblgenomes.org/id/FBgn0030696" } ] } } ], "crossref": [ { "id": "FB:FBgn0030696", "url": "https://alliancegenome.org/gene/FB:FBgn0030696", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0030696", "url": "https://bgee.org/?page=gene&gene_id=FBgn0030696", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04087", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04087", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0030696", "url": "https://flybase.org/reports/FBgn0030696", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "32535", "url": "https://www.ncbi.nlm.nih.gov/gene/32535", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004327", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004327", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037218", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037218", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043170", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043170", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG8509", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG8509", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YLWGAAQ", "url": "https://omabrowser.org/oma/group/YLWGAAQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VXN8", "url": "https://www.orthodb.org/?gene=Q9VXN8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10012", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10012", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10012:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10012:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03095", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03095", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_573079", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573079", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "16237", "url": "https://www.rhea-db.org/rhea/16237", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q9VXN8", "url": "https://www.uniprot.org/uniprotkb/Q9VXN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VXN8-1", "url": "https://www.uniprot.org/uniprotkb/Q9VXN8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSNKLGYDVTDPTVQLLRASAFMQNGPVKQVRSLEDLDRWVRSQAYYDIIAYISNTSKAIQGHRLTQTFPVTEQMRRLSEIFDGLDHLIVEHTPKIEDSYLALPFGQVRSKAYRTWMREMYQHVFSKLDEAINVNCKHINELGQYLRRSFGNGNTLDFGPANELMFLFFLCGLFRAGILLAKDTVAAALMLFNRYVNVVRRLISTYGLTIAKDPACTIEDYYFLPYLWGAAQLSVDSPFSPMQCEQGKIMDNYRQDFMMLEIIDHLQKTRSGPLSRVALQLWSILSIPTWPQVYRGLERNYIDHVLSSFGTVEQAIFCELMSFEAVVPIMPLQRAHLGTHLIVDEKENEDELEQKYGENRWSLSPPVSRYVSMEPESFLGFQASKTHNKSKESEDERLWMMRQLVDENDPNSDMFFPDREVKGRDSLTSFAN", "length": 432, "header": "tr|Q9VXN8-1|Q9VXN8_DROME Isoform 1 of Serine/threonine-protein phosphatase 2A activator OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG8509 PE=3 SV=1 CANONICAL=Q9VXN8-1" }, "isoforms": [ { "isoform_ac": "Q9VXN8-1", "url": "https://www.uniprot.org/uniprotkb/Q9VXN8/entry#Q9VXN8-1", "sequence": { "sequence": "MSNKLGYDVTDPTVQLLRASAFMQNGPVKQVRSLEDLDRWVRSQAYYDIIAYISNTSKAIQGHRLTQTFPVTEQMRRLSEIFDGLDHLIVEHTPKIEDSYLALPFGQVRSKAYRTWMREMYQHVFSKLDEAINVNCKHINELGQYLRRSFGNGNTLDFGPANELMFLFFLCGLFRAGILLAKDTVAAALMLFNRYVNVVRRLISTYGLTIAKDPACTIEDYYFLPYLWGAAQLSVDSPFSPMQCEQGKIMDNYRQDFMMLEIIDHLQKTRSGPLSRVALQLWSILSIPTWPQVYRGLERNYIDHVLSSFGTVEQAIFCELMSFEAVVPIMPLQRAHLGTHLIVDEKENEDELEQKYGENRWSLSPPVSRYVSMEPESFLGFQASKTHNKSKESEDERLWMMRQLVDENDPNSDMFFPDREVKGRDSLTSFAN", "length": 432, "header": "tr|Q9VXN8-1|Q9VXN8_DROME Isoform 1 of Serine/threonine-protein phosphatase 2A activator OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG8509 PE=3 SV=1 CANONICAL=Q9VXN8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VXN8", "url": "https://www.uniprot.org/uniprotkb/Q9VXN8" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VXN8", "url": "https://www.uniprot.org/uniprotkb/Q9VXN8" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXN8", "url": "https://www.uniprot.org/uniprotkb/Q9VXN8" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXN8", "url": "https://www.uniprot.org/uniprotkb/Q9VXN8" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VXN8", "url": "https://www.uniprot.org/uniprotkb/Q9VXN8" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VXN8", "url": "https://www.uniprot.org/uniprotkb/Q9VXN8" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VXN8", "url": "https://www.uniprot.org/uniprotkb/Q9VXN8" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXN8", "url": "https://www.uniprot.org/uniprotkb/Q9VXN8" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXN8", "url": "https://www.uniprot.org/uniprotkb/Q9VXN8" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VXN8", "url": "https://www.uniprot.org/uniprotkb/Q9VXN8" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VXN8", "url": "https://www.uniprot.org/uniprotkb/Q9VXN8" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG8509", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG8509", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LHB2-1", "protein_name": "Serine/threonine-protein phosphatase 2A activator", "gene_name": "Ptpa", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEGERQPPPDSSEETPSATPTFIIPKKEIHTVPDMGKWKRSQAYADYIGFILTLNEGVKGKKLTFDYKVSEAIEKLVALLDTLDRWIDETPPVDQPSRFGNKAYRTWYAKLDQEAENLVATVIPTNLAAAVPEVAVYLKEAVGNSTRIDYGTGHEAAFAAFLCCLCKIGVLRVDDQVAIVFKVFDRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIWGSSQLIDHPHLEPRHFVDEKAVSENHKDYMFLQCILFITEMKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAECLEKFPVIQHFKFGSLLPIHPVTSG", "length": 323 }, "evidence": [ { "id": "RGD:1308354", "url": "https://alliancegenome.org/gene/RGD:1308354#orthology", "database": "AGR" }, { "id": "MGI:1346006", "url": "https://alliancegenome.org/gene/MGI:1346006#orthology", "database": "AGR" }, { "id": "HGNC:9308", "url": "https://alliancegenome.org/gene/HGNC:9308#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040801-11", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040801-11#orthology", "database": "AGR" }, { "id": "FB:FBgn0030696", "url": "https://alliancegenome.org/gene/FB:FBgn0030696#orthology", "database": "AGR" }, { "id": "SGD:S000006073", "url": "https://alliancegenome.org/gene/SGD:S000006073#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A2CF49-1", "protein_name": "Serine/threonine-protein phosphatase 2A activator", "gene_name": "ptpa", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAETEQASGSSHEDDKPPSSVGFNFMVPKKEISMVPDMGKWKRSQAYADYIGFILTLNEGVKGKKLTCEYQVSETVEKLLALLGTLDQWIDETPPVDQPSRFGNKAFRTWYAKLDQEAEALVAGVLPAERQDAAPEIAVYLKESVGNSTRIDYGTGHEAAFAAFLCCLCKVGALRMEDQLAIIFNVFDKYLRVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIWGSSQLIDHPTLEPRHFVEEKVVNEYHQDYMFLECIKFINEMKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAECLEKFPVIQHFKFGSLLSIQPVKP", "length": 324 }, "evidence": [ { "id": "RGD:1308354", "url": "https://alliancegenome.org/gene/RGD:1308354#orthology", "database": "AGR" }, { "id": "MGI:1346006", "url": "https://alliancegenome.org/gene/MGI:1346006#orthology", "database": "AGR" }, { "id": "HGNC:9308", "url": "https://alliancegenome.org/gene/HGNC:9308#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040801-11", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040801-11#orthology", "database": "AGR" }, { "id": "FB:FBgn0030696", "url": "https://alliancegenome.org/gene/FB:FBgn0030696#orthology", "database": "AGR" }, { "id": "SGD:S000006073", "url": "https://alliancegenome.org/gene/SGD:S000006073#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P40454-1", "protein_name": "Serine/threonine-protein phosphatase 2A activator 1", "gene_name": "RRD1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSLDRVDWPHATFSTPVKRIFDTQTTLDFQSSLAIHRIKYHLHKYTTLISHCSDPDPHATASSIAMVNGLMGVLDKLAHLIDETPPLPGPRRYGNLACREWHHKLDERLPQWLQEMLPSEYHEVVPELQYYLGNSFGSSTRLDYGTGHELSFMATVAALDMLGMFPHMRGADVFLLFNKYYTIMRRLILTYTLEPAGSHGVWGLDDHFHLVYILGSSQWQLLDAQAPLQPREILDKSLVREYKDTNFYCQGINFINEVKMGPFEEHSPILYDIAVTVPRWSKVCKGLLKMYSVEVLKKFPVVQHFWFGTGFFPWVNIQNGTDLPVFEEKEEESIEQANAGSPGREQTSTRFPTSTSMPPPGVPPSGNNINYLLSHQNQSHRNQTSFSRDRLRR", "length": 393 }, "evidence": [ { "id": "RGD:1308354", "url": "https://alliancegenome.org/gene/RGD:1308354#orthology", "database": "AGR" }, { "id": "MGI:1346006", "url": "https://alliancegenome.org/gene/MGI:1346006#orthology", "database": "AGR" }, { "id": "HGNC:9308", "url": "https://alliancegenome.org/gene/HGNC:9308#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040801-11", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040801-11#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P58389-1", "protein_name": "Serine/threonine-protein phosphatase 2A activator", "gene_name": "Ptpa", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEGERQPPPDSSEETPPTTQNFIIPKKEIHTVPDMGKWKRSQAYADYIGFILTLNEGVKGKKLTFDYKVSEAIEKLVALLDTLDRWIDETPPVDQPSRFGNKAYRTWYAKLDQEAENLVATVVPTHLAAAVPEVAVYLKEAVGNSTRIDYGTGHEAAFAAFLCCLCKIGVLRVDDQVAIVFKVFDRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIWGSSQLIDHPHLEPRHFVDEKAVSENHKDYMFLQCILFITEMKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAECLEKFPVIQHFKFGSLLPIHPVTSG", "length": 323 }, "evidence": [ { "id": "RGD:1308354", "url": "https://alliancegenome.org/gene/RGD:1308354#orthology", "database": "AGR" }, { "id": "MGI:1346006", "url": "https://alliancegenome.org/gene/MGI:1346006#orthology", "database": "AGR" }, { "id": "HGNC:9308", "url": "https://alliancegenome.org/gene/HGNC:9308#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040801-11", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040801-11#orthology", "database": "AGR" }, { "id": "FB:FBgn0030696", "url": "https://alliancegenome.org/gene/FB:FBgn0030696#orthology", "database": "AGR" }, { "id": "SGD:S000006073", "url": "https://alliancegenome.org/gene/SGD:S000006073#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q12461-1", "protein_name": "Serine/threonine-protein phosphatase 2A activator 2", "gene_name": "RRD2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLPEKRLLTPDDMKLWEESPTRAHFTKFIIDLAESVKGHENSQYKEPISESINSMMNLLSQIKDITQKHPVIKDADSSRFGKVEFRDFYDEVSRNSRKILRSEFPSLTDEQLEQLSIYLDESWGNKRRIDYGSGHELNFMCLLYGLYSYGIFNLSNDSTNLVLKVFIEYLKIMRILETKYWLEPAGSHGVWGLDDYHFLPFLFGAFQLTTHKHLKPISIHNNELVEMFAHRYLYFGCIAFINKVKSSASLRWHSPMLDDISGVKTWSKVAEGMIKMYKAEVLSKLPIMQHFYFSEFLPCPDGVSPPRGHIHDGTDKDDECNFEGHVHTTWGDCCGIKLPSAIAATEMNKKHHKPIPFD", "length": 358 }, "evidence": [ { "id": "RGD:1308354", "url": "https://alliancegenome.org/gene/RGD:1308354#orthology", "database": "AGR" }, { "id": "MGI:1346006", "url": "https://alliancegenome.org/gene/MGI:1346006#orthology", "database": "AGR" }, { "id": "HGNC:9308", "url": "https://alliancegenome.org/gene/HGNC:9308#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040801-11", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040801-11#orthology", "database": "AGR" }, { "id": "FB:FBgn0030696", "url": "https://alliancegenome.org/gene/FB:FBgn0030696#orthology", "database": "AGR" }, { "id": "SGD:S000006073", "url": "https://alliancegenome.org/gene/SGD:S000006073#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q15257-1", "protein_name": "Serine/threonine-protein phosphatase 2A activator", "gene_name": "PTPA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEGERQPPPDSSEEAPPATQNFIIPKKEIHTVPDMGKWKRSQAYADYIGFILTLNEGVKGKKLTFEYRVSEMWNEVHEEKEQAAKQSVSCDECIPLPRAGHCAPSEAIEKLVALLNTLDRWIDETPPVDQPSRFGNKAYRTWYAKLDEEAENLVATVVPTHLAAAVPEVAVYLKESVGNSTRIDYGTGHEAAFAAFLCCLCKIGVLRVDDQIAIVFKVFNRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIWGSSQLIDHPYLEPRHFVDEKAVNENHKDYMFLECILFITEMKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAECLEKFPVIQHFKFGSLLPIHPVTSG", "length": 358 }, "evidence": [ { "id": "RGD:1308354", "url": "https://alliancegenome.org/gene/RGD:1308354#orthology", "database": "AGR" }, { "id": "MGI:1346006", "url": "https://alliancegenome.org/gene/MGI:1346006#orthology", "database": "AGR" }, { "id": "HGNC:9308", "url": "https://alliancegenome.org/gene/HGNC:9308#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040801-11", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040801-11#orthology", "database": "AGR" }, { "id": "FB:FBgn0030696", "url": "https://alliancegenome.org/gene/FB:FBgn0030696#orthology", "database": "AGR" }, { "id": "SGD:S000006073", "url": "https://alliancegenome.org/gene/SGD:S000006073#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VNG7-1", "protein_name": "Serine/threonine-protein phosphatase 2A activator", "gene_name": "Dmel\\CG2104", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEPQSEVNPKRVAAFFRRSNIGPVCRVQSSSDMEAWLASRAYFTLITYLNDVSAEIQGIRNTDLFPISKNIKRLTTIFEQLDSMIVANSPAPLVLGANMDSRTKSYRRWAHGMLRDIYKIVEKAVPSSKCRHVNELGVYLSGSFGSSAKIEYGTGHELSFLFFVCALFKAEILDKEQDLAASALVLFDRYLHFVRRLQVTYSVNSSNWHGGYSLDKFQFVPFVWGFAQLCHEAPFSPKKMLDEDTIAKYRDAYMLINCVGHMATTNVGTFARHSSQLWSLAALSSWTKIHRSLMFMYMEDILMDIDNLNALRFGELMSFEEDKSGRHLGSARMGVKSPLRRQMAEDPDDQDQDQDLTSRSGTPSISRSEQNDSARKKAKVEETSSDCMSNSGLSLGSECTSLSGVSVHLPTWLDDCTATSKNAF", "length": 424 }, "evidence": [ { "id": "RGD:1308354", "url": "https://alliancegenome.org/gene/RGD:1308354#orthology", "database": "AGR" }, { "id": "MGI:1346006", "url": "https://alliancegenome.org/gene/MGI:1346006#orthology", "database": "AGR" }, { "id": "HGNC:9308", "url": "https://alliancegenome.org/gene/HGNC:9308#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040801-11", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040801-11#orthology", "database": "AGR" }, { "id": "SGD:S000006073", "url": "https://alliancegenome.org/gene/SGD:S000006073#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VQQ0-1", "protein_name": "Serine/threonine-protein phosphatase 2A activator", "gene_name": "Ptpa", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MASGINQAAGKLPAIAKKVQNLGDMGVWQKSRAFHDLIGYINGTSSAIQGIKTTDEIFESEMLKKLLRLFDALEKLVEQNPPLEQPQRFGNKAYRDWAQAMRELLPELLEQLLPDDKKRYQVELGQYLTESFGNATRIDYGTGHELSFLFFLCSLFKAEILQERDIVSAALRLFNRYLELARQLQRTYNMEPAGSQGVWSLDDFQFVPFIWGSAQLAVKSPFDPSKFVDEAIITEYKDHFMFISCIDYICKVKTGHFGEHSNQLWSITDVPTWAKINAGLVKMYQKEILSKFPVIQHVYFGELMTFEPVSSGTTLSNARLGHVAPPPSKRICIGTPNLVPPVPVATAPPPPAESLSIEQNVGDSSSESSDNSVVLRPSTSSSSLVAAAEGSGDKPSKE", "length": 398 }, "evidence": [ { "id": "RGD:1308354", "url": "https://alliancegenome.org/gene/RGD:1308354#orthology", "database": "AGR" }, { "id": "MGI:1346006", "url": "https://alliancegenome.org/gene/MGI:1346006#orthology", "database": "AGR" }, { "id": "HGNC:9308", "url": "https://alliancegenome.org/gene/HGNC:9308#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040801-11", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040801-11#orthology", "database": "AGR" }, { "id": "SGD:S000006073", "url": "https://alliancegenome.org/gene/SGD:S000006073#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VXN8", "url": "https://www.uniprot.org/uniprotkb/Q9VXN8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VXN8", "url": "https://www.uniprot.org/uniprotkb/Q9VXN8" } ], "pmid": "" }, { "name": "protein phosphatase type 2A complex", "id": "GO:0000159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000159", "evidence": [ { "database": "UniProtKB", "id": "Q9VXN8", "url": "https://www.uniprot.org/uniprotkb/Q9VXN8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein tyrosine phosphatase activator activity", "id": "GO:0008160", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008160", "evidence": [ { "database": "UniProtKB", "id": "Q9VXN8", "url": "https://www.uniprot.org/uniprotkb/Q9VXN8" } ], "pmid": "" }, { "name": "peptidyl-prolyl cis-trans isomerase activity", "id": "GO:0003755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003755", "evidence": [ { "database": "UniProtKB", "id": "Q9VXN8", "url": "https://www.uniprot.org/uniprotkb/Q9VXN8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mitotic spindle organization", "id": "GO:0007052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007052", "evidence": [ { "database": "UniProtKB", "id": "Q9VXN8", "url": "https://www.uniprot.org/uniprotkb/Q9VXN8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 388, "end_pos": 390, "annotation": "n_glycosylation_sequon" }, { "start_pos": 55, "end_pos": 57, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16237", "name": "", "equation": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P25007-1", "Q9V3G3-1", "P15425-1", "P54353-1", "P54397-1", "Q9VL78-1", "P48375-1", "A0A0B4K7C5-1", "Q9W227-1", "Q9VGK3-1", "Q9VBU4-1", "Q9XYZ6-1", "Q9VNG7-1", "Q9W0Q2-1", "Q9VXN8-1", "Q9VQQ0-1", "Q8IRJ5-1", "Q9VAW1-1" ], "evidence": [ { "id": "16237", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16237" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A0B4K7C5", "gene_name": "Fkbp14", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A0B4K7C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7C5" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A0B4K7C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0B4K7C5" } ] } ] }, { "uniprot_ac": "P15425", "gene_name": "ninaA", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P15425", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P15425" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P15425", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P15425" } ] } ] }, { "uniprot_ac": "P25007", "gene_name": "Cyp1", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P25007", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P25007" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P25007", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P25007" } ] } ] }, { "uniprot_ac": "P48375", "gene_name": "Fkbp12", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P48375", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48375" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P48375", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48375" } ] } ] }, { "uniprot_ac": "P54353", "gene_name": "dod", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P54353", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P54353" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P54353", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P54353" } ] } ] }, { "uniprot_ac": "P54397", "gene_name": "Fkbp39", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "P54397", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P54397" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "P54397", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P54397" } ] } ] }, { "uniprot_ac": "Q8IRJ5", "gene_name": "Dmel\\CG32845", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "Q8IRJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8IRJ5" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "Q8IRJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8IRJ5" } ] } ] }, { "uniprot_ac": "Q9V3G3", "gene_name": "cyp33", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "Q9V3G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9V3G3" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "Q9V3G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9V3G3" } ] } ] }, { "uniprot_ac": "Q9VAW1", "gene_name": "Moca-cyp", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "Q9VAW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VAW1" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "Q9VAW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VAW1" } ] } ] }, { "uniprot_ac": "Q9VBU4", "gene_name": "Dmel\\CG11858", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "Q9VBU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VBU4" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "Q9VBU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VBU4" } ] } ] }, { "uniprot_ac": "Q9VGK3", "gene_name": "Dmel\\CG14715", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "Q9VGK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VGK3" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "Q9VGK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VGK3" } ] } ] }, { "uniprot_ac": "Q9VL78", "gene_name": "Fkbp59", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "Q9VL78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VL78" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "Q9VL78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VL78" } ] } ] }, { "uniprot_ac": "Q9VNG7", "gene_name": "Dmel\\CG2104", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "Q9VNG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VNG7" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "Q9VNG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VNG7" } ] } ] }, { "uniprot_ac": "Q9VQQ0", 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MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VXQ3", "url": "https://www.uniprot.org/uniprotkb/Q9VXQ3" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VXQ3", "url": "https://www.uniprot.org/uniprotkb/Q9VXQ3" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXQ3", "url": "https://www.uniprot.org/uniprotkb/Q9VXQ3" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXQ3", "url": "https://www.uniprot.org/uniprotkb/Q9VXQ3" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VXQ3", "url": "https://www.uniprot.org/uniprotkb/Q9VXQ3" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VXQ3", "url": "https://www.uniprot.org/uniprotkb/Q9VXQ3" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VXQ3", "url": "https://www.uniprot.org/uniprotkb/Q9VXQ3" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXQ3", "url": "https://www.uniprot.org/uniprotkb/Q9VXQ3" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXQ3", "url": "https://www.uniprot.org/uniprotkb/Q9VXQ3" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VXQ3", "url": "https://www.uniprot.org/uniprotkb/Q9VXQ3" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VXQ3", "url": "https://www.uniprot.org/uniprotkb/Q9VXQ3" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG8239", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG8239", "resource": "KEGG Pathway" }, { "id": "R-DME-446199", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-446199", "resource": "Reactome", "description": "Synthesis of dolichyl-phosphate" }, { "id": "R-DME-9969896", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9969896", "resource": "Reactome", "description": "Lanosterol biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AB49-1", "protein_name": "Diphosphomevalonate decarboxylase", "gene_name": "MVD", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASEQQPVVVTCTAPVNIAVIKYWGKRDEELILPINSSLSVTLHQHQLKTTTTAAISKDFTKDRIWLNGREEDVGQPRIQACLREIRRLARKRKSDGDEDALPLCLSYKVHVASVNNFPTAAGLASSAAGFACLACALARVYGVEGDLSEVARRGSGSACRSLYGGFVEWQMGQRADGKDSIAQQVAPESHWPELRVLILVVSAEKKLMGSTAGMQTSVETSALLRFRAKALVPARMAEMARCIRERDFQAFGQLTMKDSNQFHATCLDTFPPISYLSDTSQRVIRLVHRFNAHHGCTKVAYSFDAGPNAVIFALDDTVPEFVAAVQHSFPPEPNGDKFLQGLPVEPALLSDELKAALGTDPTPGGIRYIIATQVGPGPQVLDDPGAHLLGPDGLPKLAS", "length": 400 }, "evidence": [ { "id": "Q9VXQ3", "url": "https://omabrowser.org/oma/group/Q9VXQ3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F4JCU3-1", "protein_name": "Diphosphomevalonate decarboxylase MVD2, peroxisomal", "gene_name": "MVD2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATEKWVFMVTAQTPTNIAVIKYWGKRDEVRILPVNDSISVTLDPDHLCTVTTVAVSPAFDRDRMWLNGKEISLSGSRYQNCLREIRGRAGDVEDMEKGIKIRKKDWEKLNLHIASHNNFPTAAGLASSAAGFACLVFSLAKLMNVDEDPSHLSAIARQGSGSACRSLFGGFVKWTMGSKEDGSDSVAVQLADEKHWDDLVIIIAVVSSRQKETSSTSGMRESVETSLLLQHRAKEVVPKRILQMEEAIKNRDFASFTQLTCTDSNQFHAVCLDTSPPIFYMNDTSHRIISLVEKWNRSEGTPQVAYTFDAGPNAVLIARNRKVAVQLLQGLLYYFPPKSDTDMKSYVVGDNSILKEAGLDGASGVENLQPPPEIKDNIGSQDQKGEVSYFICTRPGKGPIVLHDQTQALLDPETGLPK", "length": 419 }, "evidence": [ { "id": "Q9VXQ3", "url": "https://omabrowser.org/oma/group/Q9VXQ3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "G3GRT8-1", "protein_name": "Diphosphomevalonate decarboxylase", "gene_name": "Mvd", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASEKPQDLVVTCTAPVNIAVIKYWGKRDEALILPINSSLSVTLHQDQLKTITTAAISKDFTEDRIWLNGREEDVGQPRLQACLREIRRLARKRRSTGDGDALPLSLSYKVHVASENNFPTAAGLASSAAGYACLAYTLARVYGVEGDLSEVARRGSGSACRSLYGGFVEWQMGEQADGKDSIAQQIAPEWHWPQLRVLILVVSAEKKQMGSTVGMQTSVETSTLLKFRAESIVPERMKEMTHCIQERDFQAFAQLTMKDSNQFHATCLDTFPPISYLNDTSRRIIQLVHCFNTHHGQTKVAYTFDAGPNAVIFTLDDTVAEFVAAVRHSFPPATNGDKFLKGLPVTPVLLSDELKAALAMEPSPGGVQYIIATQVGPGPQVLDSSNAHLLGPDGLPQQDP", "length": 401 }, "evidence": [ { "id": "Q9VXQ3", "url": "https://omabrowser.org/oma/group/Q9VXQ3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P32377-1", "protein_name": "Diphosphomevalonate decarboxylase", "gene_name": "MVD1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTVYTASVTAPVNIATLKYWGKRDTKLNLPTNSSISVTLSQDDLRTLTSAATAPEFERDTLWLNGEPHSIDNERTQNCLRDLRQLRKEMESKDASLPTLSQWKLHIVSENNFPTAAGLASSAAGFAALVSAIAKLYQLPQSTSEISRIARKGSGSACRSLFGGYVAWEMGKAEDGHDSMAVQIADSSDWPQMKACVLVVSDIKKDVSSTQGMQLTVATSELFKERIEHVVPKRFEVMRKAIVEKDFATFAKETMMDSNSFHATCLDSFPPIFYMNDTSKRIISWCHTINQFYGETIVAYTFDAGPNAVLYYLAENESKLFAFIYKLFGSVPGWDKKFTTEQLEAFNHQFESSNFTARELDLELQKDVARVILTQVGSGPQETNESLIDAKTGLPKE", "length": 396 }, "evidence": [ { "id": "MGI:2179327", "url": "https://alliancegenome.org/gene/MGI:2179327#orthology", "database": "AGR" }, { "id": "HGNC:7529", "url": "https://alliancegenome.org/gene/HGNC:7529#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-127", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-127#orthology", "database": "AGR" }, { "id": "RGD:621292", "url": "https://alliancegenome.org/gene/RGD:621292#orthology", "database": "AGR" }, { "id": "FB:FBgn0030683", "url": "https://alliancegenome.org/gene/FB:FBgn0030683#orthology", "database": "AGR" }, { "id": "SGD:S000005326", "url": "https://alliancegenome.org/gene/SGD:S000005326#orthology", "database": "AGR" }, { "id": "Q9VXQ3", "url": "https://omabrowser.org/oma/group/Q9VXQ3/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P53602-1", "protein_name": "Diphosphomevalonate decarboxylase", "gene_name": "MVD", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASEKPLAAVTCTAPVNIAVIKYWGKRDEELVLPINSSLSVTLHQDQLKTTTTAVISKDFTEDRIWLNGREEDVGQPRLQACLREIRCLARKRRNSRDGDPLPSSLSCKVHVASVNNFPTAAGLASSAAGYACLAYTLARVYGVESDLSEVARRGSGSACRSLYGGFVEWQMGEQADGKDSIARQVAPESHWPELRVLILVVSAEKKLTGSTVGMRASVETSPLLRFRAESVVPARMAEMARCIRERDFPSFAQLTMKDSNQFHATCLDTFPPISYLNAISWRIIHLVHRFNAHHGDTKVAYTFDAGPNAVIFTLDDTVAEFVAAVWHGFPPGSNGDTFLKGLQVRPAPLSAELQAALAMEPTPGGVKYIIVTQVGPGPQILDDPCAHLLGPDGLPKPAA", "length": 400 }, "evidence": [ { "id": "MGI:2179327", "url": "https://alliancegenome.org/gene/MGI:2179327#orthology", "database": "AGR" }, { "id": "HGNC:7529", "url": "https://alliancegenome.org/gene/HGNC:7529#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-127", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-127#orthology", "database": "AGR" }, { "id": "RGD:621292", "url": "https://alliancegenome.org/gene/RGD:621292#orthology", "database": "AGR" }, { "id": "FB:FBgn0030683", "url": "https://alliancegenome.org/gene/FB:FBgn0030683#orthology", "database": "AGR" }, { "id": "SGD:S000005326", "url": "https://alliancegenome.org/gene/SGD:S000005326#orthology", "database": "AGR" }, { "id": "Q9VXQ3", "url": "https://omabrowser.org/oma/group/Q9VXQ3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q0P570-1", "protein_name": "Diphosphomevalonate decarboxylase", "gene_name": "MVD", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MASEKPIVVVTCTAPVNIAVVKYWGKRDEELILPINSSLSVTLHQDQLKTTTTAAISRDFTEDRIWLNGREEDMGHPRLQACLREIRRLARKRRSDGHEDPLPLSLSYKVHVASENNFPTAAGLASSAAGYACLAYTLARVYGVDSDLSEVARRGSGSACRSLYGGFVEWQMGERPDGKDSVACQVAPESHWPELRVLILVVSAERKPMGSTAGMQTSVETSALLKFRAEALVPPRMAEMTRCIRERNFQAFGQLTMKDSNQFHATCLDTFPPISYLSDTSRRIIQLVHRFNAHHGQTKVAYTFDAGPNAVVFTLDDTVAEFVAAVRHSFPPESNGDKFLKGLPVEPVLLSDELKAVLGMDPVPGSIRYIIATQVGPGPQVLDDPGAHLLGPDGLPKPAA", "length": 400 }, "evidence": [ { "id": "Q9VXQ3", "url": "https://omabrowser.org/oma/group/Q9VXQ3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54YQ9-1", "protein_name": "Diphosphomevalonate decarboxylase", "gene_name": "mvd", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVLASVTCTAPVNIAVIKYWGKRDENIILPLNSSLSGTLHQDDLKTTTTIVASEDYTEDELYLNGKKEDINAVRYQNVLKMIRSRATKLMDKKHCVHIASINNFPTAAGLASSASGYCCLVFTLAQMYGVDGDISGIARLGSGSACRSMYGGFVKWEMGTKDDGSDSIAVQVQPESHWPDMNIIVLVVNDKKKETSSTDGMQKSAATSVMMKERCAVTVPNRMRDIEEAINKKDFQTFGDITMKDSDDFHEVCATTTPPIYYLNDTSRYIMNLIHRYNKLSGSIKCAYTFDAGPNACIYLPAESTTEVLSLFMKHFPGDDMQTYYRGPKENIPSIENFVPSEKLASLYTPDTTFVNSLKYILHTKVGPGPQILSESESLIDNTTGLPKQLN", "length": 391 }, "evidence": [ { "id": "Q9VXQ3", "url": "https://omabrowser.org/oma/group/Q9VXQ3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5U403-1", "protein_name": "Diphosphomevalonate decarboxylase", "gene_name": "mvd", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSENILQDLEMVTCTAPVNIAVIKYWGKRDEDLILPVNASLSVTLHQDHLRTTTTIACSRSFHKDCIWLNGKEQDISHPRLQSCLLEIRRLAQRRKNTGDPASDVSNKVHICSVNNFPTAAGLASSAAGYACLVYTLSQLFNVEGELSGVARQGSGSACRSLYGGFVQWKLGEQSDGKDSIAEQVASELYWPELRVLILVVSAEQKSVGSTSGMHTSVETSHLLKYRADAVVPGRMEEMIRAIRLRDFPKFGELTMKDSNQFHAICLDTYPPIFYLNNISHQIISLVHRYNQYYGETRVAYTFDAGPNAVIYSLQDYLPEFVEVVRHFFPPEVNEEEFFKGLPVCPADLSEEMIRDINMKPTPNGIRYMISTKAGPGPRVVEDPNLHLLGADGLPKKSAV", "length": 400 }, "evidence": [ { "id": "MGI:2179327", "url": "https://alliancegenome.org/gene/MGI:2179327#orthology", "database": "AGR" }, { "id": "HGNC:7529", "url": "https://alliancegenome.org/gene/HGNC:7529#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-127", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-127#orthology", "database": "AGR" }, { "id": "RGD:621292", "url": "https://alliancegenome.org/gene/RGD:621292#orthology", "database": "AGR" }, { "id": "FB:FBgn0030683", "url": "https://alliancegenome.org/gene/FB:FBgn0030683#orthology", "database": "AGR" }, { "id": "SGD:S000005326", "url": "https://alliancegenome.org/gene/SGD:S000005326#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q62967-1", "protein_name": "Diphosphomevalonate decarboxylase", "gene_name": "Mvd", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASEKPQDLMVTCTAPVNIAVIKYWGKRDEALILPINSSLSVTLHQDQLKTTTTAAISKDFTEDRIWLNGREEDVGQPRLQACLREIRRLARKRRSTGDGDALPLSLGYKVHVASVNNFPTAAGLASSAAGYACLAYTLARVYGVEGDLSEVARRGSGSACRSLYGGFVEWQMGEQADGKDSIARQIAPEWHWPQLRVLILVVSAEKKPTGSTVGMQTSVATSTLLKFRAESIVPERMKEMTRCIQEQDFQAFAQLTMKDSNQFHATCLDTFPPISYLNDTSRRIIQLVHRFNAHHGQTKVAYTFDAGPNAVIFTLEDTVAEFVAAVRHSFPPAANGDKFLKGLQVAPVLLSDELKTSLATEPSPGGVQYIIATQVGPGPQVLDDPHHHLLGPDGLPQRDL", "length": 401 }, "evidence": [ { "id": "MGI:2179327", "url": "https://alliancegenome.org/gene/MGI:2179327#orthology", "database": "AGR" }, { "id": "HGNC:7529", "url": "https://alliancegenome.org/gene/HGNC:7529#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-127", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-127#orthology", "database": "AGR" }, { "id": "RGD:621292", "url": "https://alliancegenome.org/gene/RGD:621292#orthology", "database": "AGR" }, { "id": "FB:FBgn0030683", "url": "https://alliancegenome.org/gene/FB:FBgn0030683#orthology", "database": "AGR" }, { "id": "SGD:S000005326", "url": "https://alliancegenome.org/gene/SGD:S000005326#orthology", "database": "AGR" }, { "id": "Q9VXQ3", "url": "https://omabrowser.org/oma/group/Q9VXQ3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q99JF5-1", "protein_name": "Diphosphomevalonate decarboxylase", "gene_name": "Mvd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASEKPQDLMVTCTAPVNIAVIKYWGKRDEALILPINSSLSVTLHQDQLKTTTTVAISKDFTEDRIWLNGREEDVGQPRLQACLREIRRLARKRRSTEDGDTLPLSLSYKVHVASVNNFPTAAGLASSAAGYACLAYTLAQVYGVEGDLSEVARRGSGSACRSLYGGFVEWQMGEQADGKDSIARQIAPEWHWPQLRILILVVSADKKQTGSTVGMQTSVETSTLLKFRAESVVPERMKEMTRCIQEQDFQGFAQLTMKDSNQFHATCLDTFPPISYLNDTSRRIIQLVHRFNTHQGQTKVAYTFDAGPNAVIFTLEDTVAEFVAAVRHSFPPAANGDKFLKGLQVAPVLLSDELKAALAVEPSPGGVQYIIATQVGPGPQVLDDTHDHLLGQDGLPQRDL", "length": 401 }, "evidence": [ { "id": "MGI:2179327", "url": "https://alliancegenome.org/gene/MGI:2179327#orthology", "database": "AGR" }, { "id": "HGNC:7529", "url": "https://alliancegenome.org/gene/HGNC:7529#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-127", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-127#orthology", "database": "AGR" }, { "id": "RGD:621292", "url": "https://alliancegenome.org/gene/RGD:621292#orthology", "database": "AGR" }, { "id": "FB:FBgn0030683", "url": "https://alliancegenome.org/gene/FB:FBgn0030683#orthology", "database": "AGR" }, { "id": "SGD:S000005326", "url": "https://alliancegenome.org/gene/SGD:S000005326#orthology", "database": "AGR" }, { "id": "Q9VXQ3", "url": "https://omabrowser.org/oma/group/Q9VXQ3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VXQ3", "url": "https://www.uniprot.org/uniprotkb/Q9VXQ3" } ], "pmid": "" }, { "name": "diphosphomevalonate decarboxylase activity", "id": "GO:0004163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004163", "evidence": [ { "database": "UniProtKB", "id": "Q9VXQ3", "url": "https://www.uniprot.org/uniprotkb/Q9VXQ3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9VXQ3", "url": "https://www.uniprot.org/uniprotkb/Q9VXQ3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cholesterol biosynthetic process", "id": "GO:0006695", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006695", "evidence": [ { "database": "UniProtKB", "id": "Q9VXQ3", "url": "https://www.uniprot.org/uniprotkb/Q9VXQ3" } ], "pmid": "" }, { "name": "isopentenyl diphosphate biosynthetic process, mevalonate pathway", "id": "GO:0019287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019287", "evidence": [ { "database": "UniProtKB", "id": "Q9VXQ3", "url": "https://www.uniprot.org/uniprotkb/Q9VXQ3" } ], "pmid": "" }, { "name": "isoprenoid biosynthetic process", "id": "GO:0008299", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008299", "evidence": [ { "database": "UniProtKB", "id": "Q9VXQ3", "url": "https://www.uniprot.org/uniprotkb/Q9VXQ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 30, "end_pos": 32, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "23732", "name": "", "equation": "(R)-5-diphosphomevalonate + ATP = isopentenyl diphosphate + ADP + CO2 + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VXQ3-1" ], "evidence": [ { "id": "23732", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/23732" } ] }, { "id": "R-DME-191414", "name": "MVD decarboxylates MVA5PP to IPPP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-191403" ], "output_participant_list": [], "enzyme_list": [ "Q9VXQ3-1" ], "evidence": [ { "id": "R-DME-191414", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-191414" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-191403", "participant_name": "MVA5PP [cytosol]", "crossref": [ { "id": "57557", "database": "ChEBI", "url": "" }, { "id": "ZINC000008216889", "database": "ZINC", "url": "" }, { "id": "C01143", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "Q9VXQ3", "gene_name": "Mvd", "activity": [ { "ec_number": "4.1.1.33", "activity": "(R)-5-diphosphomevalonate + ATP = isopentenyl diphosphate + ADP + phosphate + CO2.", "evidence": [ { "id": "Q9VXQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXQ3" } ] }, { "ec_number": "4.1.1.33", "activity": "", "evidence": [ { "id": "Q9VXQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXQ3" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VXQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXQ3" }, { "id": "PF22700", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22700" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Diphosphomevalonate decarboxylase-like N-terminal", "eco_id": "ECO_0000259", "start_pos": 8, "end_pos": 174, "start_aa": "Ala", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q9VXQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXQ3" }, { "id": "PF18376", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18376" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mvd1 C-terminal", "eco_id": "ECO_0000259", "start_pos": 188, "end_pos": 373, "start_aa": "Val", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "4.1.1.33", "ec_name": "(R)-5-diphosphomevalonate + ATP = isopentenyl diphosphate + ADP + phosphate + CO2.", "evidence": [ { "id": "4.1.1.33", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.33" }, { "id": "4.1.1.33", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=4.1.1.33" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 30, "end_pos": 32 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VXT0-1", "uniprot_ac": "Q9VXT0", "uniprot_id": "Q9VXT0_DROME", "mass": { "chemical_mass": 50901.0, "monoisotopic_mass": 50901.0 }, "refseq": { "ac": "NP_001285279", "name": "uncharacterized protein, isoform B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285279" }, "gene_names": [ { "name": "Dmel\\CG8097", "type": "recommended", "evidence": [ { "id": "Q9VXT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXT0" } ] }, { "name": "CG8097", "type": "synonym", "evidence": [ { "id": "NP_001285279", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285279" }, { "id": "Q9VXT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXT0" } ] }, { "name": "Dmel\\CG8097", "type": "synonym", "evidence": [ { "id": "NP_001285279", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285279" } ] }, { "name": "Dmel_CG8097", "type": "synonym", "evidence": [ { "id": "Q9VXT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXT0" } ] } ], "protein_names": [ { "name": "DALR anticodon binding domain-containing protein", "type": "recommended", "evidence": [ { "id": "Q9VXT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXT0/entry#names_and_taxonomy" } ] }, { "name": "ArgRS-like protein", "type": "synonym", "evidence": [ { "id": "NP_001285279", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285279" } ] }, { "name": "CG8097-PB", "type": "synonym", "evidence": [ { "id": "NP_001285279", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285279" } ] }, { "name": "uncharacterized protein, isoform B", "type": "synonym", "evidence": [ { "id": "NP_001285279", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285279" } ] } ], "function": [], "disease": [ { "disease_id": "DOID:0112220", "recommended_name": { "id": "DOID:0112220", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0112220", "name": "developmental and epileptic encephalopathy 86", "description": "A developmental and epileptic encephalopathy characterized by severe and persistent seizures associated with EEG abnormalities beginning in the first few months of life, global developmental delay, severe motor deficits, dystonic movements, and dysmorphic facial features that has_material_basis_in homozygous or compound heterozygous mutation in the DALRD2 gene on chromosome 3p21.31." }, "synonyms": [ { "id": "DOID:0112220", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0112220", "name": "DEE86", "description": "" }, { "id": "DOID:0112220", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0112220", "name": "early infantile epileptic encephalopathy 86", "description": "" }, { "id": "MONDO:0030054", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0030054", "name": "developmental and epileptic encephalopathy, 86", "description": "" }, { "id": "MONDO:0030054", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0030054", "name": "DEE86", "description": "" }, { "id": "MONDO:0030054", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0030054", "name": "EIEE86", "description": "" }, { "id": "MONDO:0030054", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0030054", "name": "EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 86", "description": "" }, { "id": "MONDO:0030054", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0030054", "name": "developmental and epileptic encephalopathy 86", "description": "" }, { "id": "MONDO:0030054", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0030054", "name": "epileptic encephalopathy, early infantile, 86", "description": "" }, { "id": "MIM:618910", "resource": "MIM", "url": "https://www.omim.org/entry/618910", "name": "Developmental and epileptic encephalopathy 86", "description": "Developmental and epileptic encephalopathy 86" } ], "unlinked_id_list": [], "evidence": [ { "id": "0112220", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112220" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VXT0", "url": "https://www.uniprot.org/uniprotkb/Q9VXT0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG8097", "url": "https://www.uniprot.org/uniprotkb/Q9VXT0", "locus": { "chromosome": "X", "start_pos": 15585249, "end_pos": 15583159, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0030660", "url": "https://www.ensemblgenomes.org/id/FBgn0030660" } ] } } ], "crossref": [ { "id": "FB:FBgn0030660", "url": "https://alliancegenome.org/gene/FB:FBgn0030660", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0030660", "url": "https://bgee.org/?page=gene&gene_id=FBgn0030660", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0030660", "url": "https://flybase.org/reports/FBgn0030660", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "32495", "url": "https://www.ncbi.nlm.nih.gov/gene/32495", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009080", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009080", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037380", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037380", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG8097", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG8097", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DMLLIAM", "url": "https://omabrowser.org/oma/group/DMLLIAM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VXT0", "url": "https://www.orthodb.org/?gene=Q9VXT0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16043", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16043", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16043:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16043:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05746", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05746", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001285279", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285279", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VXT0", "url": "https://www.uniprot.org/uniprotkb/Q9VXT0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VXT0-1", "url": "https://www.uniprot.org/uniprotkb/Q9VXT0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDCNPRLQVGQQLFEFFTKPEKPDESGGDVAAPLLLKKFGKLIRYNNDDLTEQGDLTLAAIPRYWQKYLKSQGLKLRIDGDELLPSPVDRLELMEHSRKWRFPLAEITVLNKERYSLRFQRHPIIAHVLNSVLTLRGDYGRSANNNQSRTICLQLQAVVGAVDGGQDLRHYRLQQLYKILLRLVDYSSWRLVEPNDRQKDTICVTVELEKCCNGKQPVEHVCLTCGPVLEPINKGASSLTVDEYLKLRCQHMELMATQRSGMCPVPMSSLDTLTKRLAAAAVIVDLFVVRHSSAVSVVRNGVGICKGASYILYNSARLEALLRKFNYEVNNCAYEKLPLLDEIDLSVLEDDVDWELIYGYLLTFPELMESIMDQLDQGHCGLHLLVHYVENLAAAFSRFYYHKKVLLQKRDELMPILYARIYLIKAVRQVLNTALAVLGIEPVDYV", "length": 446, "header": "tr|Q9VXT0-1|Q9VXT0_DROME Isoform 1 of DALR anticodon binding domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG8097 PE=4 SV=1 CANONICAL=Q9VXT0-1" }, "isoforms": [ { "isoform_ac": "Q9VXT0-1", "url": "https://www.uniprot.org/uniprotkb/Q9VXT0/entry#Q9VXT0-1", "sequence": { "sequence": "MDCNPRLQVGQQLFEFFTKPEKPDESGGDVAAPLLLKKFGKLIRYNNDDLTEQGDLTLAAIPRYWQKYLKSQGLKLRIDGDELLPSPVDRLELMEHSRKWRFPLAEITVLNKERYSLRFQRHPIIAHVLNSVLTLRGDYGRSANNNQSRTICLQLQAVVGAVDGGQDLRHYRLQQLYKILLRLVDYSSWRLVEPNDRQKDTICVTVELEKCCNGKQPVEHVCLTCGPVLEPINKGASSLTVDEYLKLRCQHMELMATQRSGMCPVPMSSLDTLTKRLAAAAVIVDLFVVRHSSAVSVVRNGVGICKGASYILYNSARLEALLRKFNYEVNNCAYEKLPLLDEIDLSVLEDDVDWELIYGYLLTFPELMESIMDQLDQGHCGLHLLVHYVENLAAAFSRFYYHKKVLLQKRDELMPILYARIYLIKAVRQVLNTALAVLGIEPVDYV", "length": 446, "header": "tr|Q9VXT0-1|Q9VXT0_DROME Isoform 1 of DALR anticodon binding domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG8097 PE=4 SV=1 CANONICAL=Q9VXT0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VXT0", "url": "https://www.uniprot.org/uniprotkb/Q9VXT0" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VXT0", "url": "https://www.uniprot.org/uniprotkb/Q9VXT0" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXT0", "url": "https://www.uniprot.org/uniprotkb/Q9VXT0" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXT0", "url": "https://www.uniprot.org/uniprotkb/Q9VXT0" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VXT0", "url": "https://www.uniprot.org/uniprotkb/Q9VXT0" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VXT0", "url": "https://www.uniprot.org/uniprotkb/Q9VXT0" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VXT0", "url": "https://www.uniprot.org/uniprotkb/Q9VXT0" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXT0", "url": "https://www.uniprot.org/uniprotkb/Q9VXT0" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXT0", "url": "https://www.uniprot.org/uniprotkb/Q9VXT0" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VXT0", "url": "https://www.uniprot.org/uniprotkb/Q9VXT0" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VXT0", "url": "https://www.uniprot.org/uniprotkb/Q9VXT0" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG8097", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG8097", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0JML8-1", "protein_name": "DALR anticodon-binding domain-containing protein 3", "gene_name": "dalrd3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEESAPFSIVSTVKALSGALRGDAGHEADISREREKLWFKESSAKNLRNRDFLAPNTVLTTLYAGGEVPSDILSAVHTLRGSGVLPIGATEVTTEGLRVCVDRCAAFRGVLCGIMPYLKPAAQRQGCVLINCPALHTKQSVPSPDTLALGQLRTILIADHLGAQLRRQGYTVSFCPALPQESDIVNFLKTLGIDWPTVPVSWTNEDREEKMKKALENSAYRDRETEKGKRRSRGEEIEGEKRGLKEDVRINLKQVVQDENLNGYDPSLGTCTVQREALCHLAQLDSATADFPASTTTALHVTSCQDEFRQQQTAMLWRAAGATALQRLVICGPVKTPGVQMNAAQYFQLRKAQMKEASEMKYGDQVEGQTWDDIIRVMTSATVRFELLSTVHTSPVTLDVQRDSGVSTKGPRGGVFVMYNCARLHTLFSSYEKGVEQGLYPEIPGGTELDFSALKEEGEWLLLFNYLIPFSEILDQSAQTLEHEGGGARVQLRTEQVCRFLVSLSKDFSSYYNRVHVLGEPLPHLFNQMFCRLLLLRALRELYHSALDSLNLPPIPQL", "length": 558 }, "evidence": [ { "id": "RGD:1359206", "url": "https://alliancegenome.org/gene/RGD:1359206#orthology", "database": "AGR" }, { "id": "MGI:1915039", "url": "https://alliancegenome.org/gene/MGI:1915039#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061103-415", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061103-415#orthology", "database": "AGR" }, { "id": "HGNC:25536", "url": "https://alliancegenome.org/gene/HGNC:25536#orthology", "database": "AGR" }, { "id": "FB:FBgn0030660", "url": "https://alliancegenome.org/gene/FB:FBgn0030660#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5D0E6-1", "protein_name": "DALR anticodon-binding domain-containing protein 3", "gene_name": "DALRD3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATRRLGVGETLGALNAALGPGGPVWIKETRTRHLRSRDFLAPHRALQARFDDGQVPEHLLHALACLQGPGVAPVLRCAPTPAGLSLQLQRSAVFERVLSAVAAYATPASPASLGQRVLLHCPALRSSPCALRLSQLRTVLVADHLARALRAHGVCVRLVPAVRDPHMLTFLQQLRVDWPAASERASSHTLRSHALEELTSANDGRTLSPGILGRLCLKELVEEQGRTAGYDPNLDNCLVTEDLLSVLAELQEALWHWPEDSHPGLAGASDTGTGGCLVVHVVSCEEEFQQQKLDLLWQKLVDKAPLRQKHLICGPVKVAGAPGTLMTAPEYYEFRHTQVCKASALKHGGDLAQDPAWTEIFGVLSVATIKFEMLSTAPQSQLFLALADSSISTKGTKSGTFVMYNCARLATLFESYKCSMEQGLYPTFPPVSSLDFSLLHDEGEWLLLFNSILPFPDLLSRTAVLDCTAPGLHIAVRTEMICKFLVQLSMDFSSYYNRVHILGEPRPHLFGQMFVRLQLLRAVREVLHTGLAMLGLPPLSHI", "length": 543 }, "evidence": [ { "id": "RGD:1359206", "url": "https://alliancegenome.org/gene/RGD:1359206#orthology", "database": "AGR" }, { "id": "MGI:1915039", "url": "https://alliancegenome.org/gene/MGI:1915039#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061103-415", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061103-415#orthology", "database": "AGR" }, { "id": "HGNC:25536", "url": "https://alliancegenome.org/gene/HGNC:25536#orthology", "database": "AGR" }, { "id": "FB:FBgn0030660", "url": "https://alliancegenome.org/gene/FB:FBgn0030660#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q641Y9-1", "protein_name": "DALR anticodon-binding domain-containing protein 3", "gene_name": "Dalrd3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATGRLGVGETLQALNAAVGPGSPVWFKETHARHLRVRDFLAPRSALQARFRDGQVPECVFRAVSCLQGPGVAPVLRCAPTPAGLSLQLQRPAVFEHVLGALASYATPAKPASPGPRVILHCPALRCNPDTLRLSQLRAVLVADHLVRVLRAHGVRVCTVPPVRDPHMSTFLQKLRVEWPSASKNTSTETLRTCVLAKFNVSKEETLPPGVLGRLCLKELVEQRHAAGYDPSIDHCLVTEDLLSVLSELQEAARHWPEDGHPAPVGGPDAGVDDCVVIHVVSCEEAFQQQKLDLLWQKVDDQVPHRQKHLVCGPVKVAGVPGTQMTAPEYHRLRHAQVCKASAQKHGGDLAQDPAWTETFDILSVATIKFEMLSTAPQGQLLLAHSTISTKGTKSGTFVMYNCARLATLFEGYKHGMEQGLYPTFPLVSSLDFSLLHDEGEWLLLFNSVLPFLDLLSQTVSLASTPGLHIPVRTEMVCKFLVQLSMDFSSYYNRVHILGEPRPHLFGQMFARLQLLRAVREVFHTGLAMLGLPPLSHI", "length": 538 }, "evidence": [ { "id": "RGD:1359206", "url": "https://alliancegenome.org/gene/RGD:1359206#orthology", "database": "AGR" }, { "id": "MGI:1915039", "url": "https://alliancegenome.org/gene/MGI:1915039#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061103-415", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061103-415#orthology", "database": "AGR" }, { "id": "HGNC:25536", "url": "https://alliancegenome.org/gene/HGNC:25536#orthology", "database": "AGR" }, { "id": "FB:FBgn0030660", "url": "https://alliancegenome.org/gene/FB:FBgn0030660#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6PJN8-1", "protein_name": "DALR anticodon-binding domain-containing protein 3", "gene_name": "Dalrd3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATGRLGVGETLEALNAAVGPGSPVWFKETHARHLRVRDFLAPRSALQARFRDGQVPECVFRAVSCLQGPGVAPVLRCAPTPAGLSLQLQRPAVFEHVLGALASYATPAKPASPGPRVVLHCPALRCNSGTLRLSQLRAVLVADHLVRVLRAHGVRVCSVPPVRDPHMSTFLQKLRVEWPTASKSTSTETLRTCVLANLNGSKEATLPPGVLGRLCLKELVEQRGTAGYDPSIDHCLVTEDVLSVLSELQEAVRHWPEGGHPGPAGRPDAGVDDCVVIHVVSCEEAFQQQKLDLLWQKLDDRAPHKQKHLVCGPVKMAGVPGTQLTAPQYYRLRHAQVCEASALKHGGDLAQDPAWTETFDILSVATIKFEMLSTAPQSQLLLAHSTISTKGTKSGTFVMYNCARLATLFEGYKHGTEQGLYPTFPLVSSLDFSLLHDEGEWLLLFNSVLPFLDLLSQTVSLAGTPGLHIPVRTEMVCKFLVQLSMDFSSYYNRVHILGEPRPHLFGQMFARLQLLRAVREVFHTGLAMLGLPPLSHI", "length": 538 }, "evidence": [ { "id": "RGD:1359206", "url": "https://alliancegenome.org/gene/RGD:1359206#orthology", "database": "AGR" }, { "id": "MGI:1915039", "url": "https://alliancegenome.org/gene/MGI:1915039#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061103-415", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061103-415#orthology", "database": "AGR" }, { "id": "HGNC:25536", "url": 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"https://www.uniprot.org/uniprotkb/Q9VXT0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "arginyl-tRNA aminoacylation", "id": "GO:0006420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006420", "evidence": [ { "database": "UniProtKB", "id": "Q9VXT0", "url": "https://www.uniprot.org/uniprotkb/Q9VXT0" } ], "pmid": "" }, { "name": "tRNA C3-cytosine methylation", "id": "GO:0106217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106217", "evidence": [ { "database": "UniProtKB", "id": "Q9VXT0", "url": "https://www.uniprot.org/uniprotkb/Q9VXT0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VXT0", "database": "UniProtKB", "url": 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"chemical_mass": 63156.0, "monoisotopic_mass": 63156.0 }, "refseq": { "ac": "NP_573045", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573045" }, "gene_names": [ { "name": "Dmel\\CG9215", "type": "recommended", "evidence": [ { "id": "Q9VXT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXT1" } ] }, { "name": "CG9215", "type": "synonym", "evidence": [ { "id": "NP_573045", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573045" }, { "id": "Q9VXT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXT1" } ] }, { "name": "Dmel\\CG9215", "type": "synonym", "evidence": [ { "id": "NP_573045", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573045" } ] }, { "name": "Dmel_CG9215", "type": "synonym", "evidence": [ { "id": "Q9VXT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXT1" } ] } ], "protein_names": [ { "name": "CG9215-PA", "type": "synonym", "evidence": [ { "id": "NP_573045", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573045" } ] }, { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "Q9VXT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXT1/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_573045", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573045" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VXT1", "url": "https://www.uniprot.org/uniprotkb/Q9VXT1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG9215", "url": "https://www.uniprot.org/uniprotkb/Q9VXT1", "locus": { "chromosome": "X", "start_pos": 15580930, "end_pos": 15582874, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0030659", "url": "https://www.ensemblgenomes.org/id/FBgn0030659" } ] } } ], "crossref": [ { "id": "FB:FBgn0030659", "url": "https://alliancegenome.org/gene/FB:FBgn0030659", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0030659", "url": "https://bgee.org/?page=gene&gene_id=FBgn0030659", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0030659", "url": "https://flybase.org/reports/FBgn0030659", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "32494", "url": "https://www.ncbi.nlm.nih.gov/gene/32494", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012934", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012934", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG9215", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG9215", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NTYKYQH", "url": "https://omabrowser.org/oma/group/NTYKYQH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VXT1", "url": "https://www.orthodb.org/?gene=Q9VXT1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515:SF49", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515:SF49", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07776", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07776", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13912", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13912", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-9843940", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9843940", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_573045", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573045", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VXT1", "url": "https://www.uniprot.org/uniprotkb/Q9VXT1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VXT1-1", "url": "https://www.uniprot.org/uniprotkb/Q9VXT1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSNNLQPRVVDLGVACLVCLAEEPEASSIYGHDPESPHMLILDKIRCCTSLQLDSSPSQLQRWPDKICKQCHLELSVSYRFHEKCTAVQKLFRSASRSTSTSAVFAAAAAAPPAPMLVDKQQEQLKLDLEQAHVRLPATLKIRRLNVEPCSSSSVSGTITTSTEPSEDVKEEKTDSLSLIPDGAMVLSLNDFQAQDSITQQAEEKDPKKQQDEDEGQAKMLELDPWDDENTPEHLYEIETPLIEESVVASPPLPLPPTHPANQQKKRTYRRVSPNVKHEKLTANVDDDFKAGSTTKRRNCERSPKICDVCGNTYKYQHALNAHMRRHNNERPYSCEVCQKAFISNVELRRHMRVHTGQKPYSCRHCERRFSDFGSSKKHERIHTGERPYVCEVCNKGFAYAHVLSAHRRTHTGKKQFQCTQCDKGFTKKTYLSAHMEQHRGSGNGEASVASSSADASSRNQNASARKESARKQQQIPESFSLDSVELEQTKVLEECIVANDFMFNEEDNAEQEANDREGLQHDDSYPYVGGYQSVDSVKELVGDLLDTEEFCDESKYMIE", "length": 560, "header": "tr|Q9VXT1-1|Q9VXT1_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG9215 PE=3 SV=1 CANONICAL=Q9VXT1-1" }, "isoforms": [ { "isoform_ac": "Q9VXT1-1", "url": "https://www.uniprot.org/uniprotkb/Q9VXT1/entry#Q9VXT1-1", "sequence": { "sequence": "MSNNLQPRVVDLGVACLVCLAEEPEASSIYGHDPESPHMLILDKIRCCTSLQLDSSPSQLQRWPDKICKQCHLELSVSYRFHEKCTAVQKLFRSASRSTSTSAVFAAAAAAPPAPMLVDKQQEQLKLDLEQAHVRLPATLKIRRLNVEPCSSSSVSGTITTSTEPSEDVKEEKTDSLSLIPDGAMVLSLNDFQAQDSITQQAEEKDPKKQQDEDEGQAKMLELDPWDDENTPEHLYEIETPLIEESVVASPPLPLPPTHPANQQKKRTYRRVSPNVKHEKLTANVDDDFKAGSTTKRRNCERSPKICDVCGNTYKYQHALNAHMRRHNNERPYSCEVCQKAFISNVELRRHMRVHTGQKPYSCRHCERRFSDFGSSKKHERIHTGERPYVCEVCNKGFAYAHVLSAHRRTHTGKKQFQCTQCDKGFTKKTYLSAHMEQHRGSGNGEASVASSSADASSRNQNASARKESARKQQQIPESFSLDSVELEQTKVLEECIVANDFMFNEEDNAEQEANDREGLQHDDSYPYVGGYQSVDSVKELVGDLLDTEEFCDESKYMIE", "length": 560, "header": "tr|Q9VXT1-1|Q9VXT1_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG9215 PE=3 SV=1 CANONICAL=Q9VXT1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VXT1", "url": "https://www.uniprot.org/uniprotkb/Q9VXT1" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VXT1", "url": "https://www.uniprot.org/uniprotkb/Q9VXT1" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXT1", "url": "https://www.uniprot.org/uniprotkb/Q9VXT1" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXT1", "url": "https://www.uniprot.org/uniprotkb/Q9VXT1" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VXT1", "url": "https://www.uniprot.org/uniprotkb/Q9VXT1" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VXT1", "url": "https://www.uniprot.org/uniprotkb/Q9VXT1" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VXT1", "url": "https://www.uniprot.org/uniprotkb/Q9VXT1" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXT1", "url": "https://www.uniprot.org/uniprotkb/Q9VXT1" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXT1", "url": "https://www.uniprot.org/uniprotkb/Q9VXT1" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VXT1", "url": "https://www.uniprot.org/uniprotkb/Q9VXT1" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VXT1", "url": "https://www.uniprot.org/uniprotkb/Q9VXT1" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], 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Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VXT6", "url": "https://www.uniprot.org/uniprotkb/Q9VXT6" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VXT6", "url": "https://www.uniprot.org/uniprotkb/Q9VXT6" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXT6", "url": "https://www.uniprot.org/uniprotkb/Q9VXT6" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXT6", "url": "https://www.uniprot.org/uniprotkb/Q9VXT6" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VXT6", "url": "https://www.uniprot.org/uniprotkb/Q9VXT6" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VXT6", "url": "https://www.uniprot.org/uniprotkb/Q9VXT6" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VXT6", "url": "https://www.uniprot.org/uniprotkb/Q9VXT6" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi 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"uniprot_canonical_ac": "Q9VXW2-1", "uniprot_ac": "Q9VXW2", "uniprot_id": "Q9VXW2_DROME", "mass": { "chemical_mass": 136281.0, "monoisotopic_mass": 136281.0 }, "refseq": { "ac": "NP_573020", "name": "pre-mRNA processing factor 5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573020" }, "gene_names": [ { "name": "Prp5", "type": "recommended", "evidence": [ { "id": "Q9VXW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXW2" } ] }, { "name": "CG6227", "type": "synonym", "evidence": [ { "id": "NP_573020", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573020" }, { "id": "Q9VXW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXW2" } ] }, { "name": "DmRH29", "type": "synonym", "evidence": [ { "id": "NP_573020", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573020" }, { "id": "Q9VXW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXW2" } ] }, { "name": "Dmel\\CG6227", "type": "synonym", "evidence": [ { "id": "NP_573020", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573020" }, { "id": "Q9VXW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXW2" } ] }, { "name": "Dmel_CG6227", "type": "synonym", "evidence": [ { "id": "Q9VXW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXW2" } ] }, { "name": "Prp5", "type": "synonym", "evidence": [ { "id": "NP_573020", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573020" } ] }, { "name": "cg6227", "type": "synonym", "evidence": [ { "id": "NP_573020", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573020" }, { "id": "Q9VXW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXW2" } ] } ], "protein_names": [ { "name": "Probable ATP-dependent RNA helicase DDX46", "type": "recommended", "evidence": [ { "id": "Q9VXW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXW2/entry#names_and_taxonomy" } ] }, { "name": "3.6.4.13", "type": "synonym", "evidence": [ { "id": "Q9VXW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXW2/entry#names_and_taxonomy" } ] }, { "name": "CG6227-PA", "type": "synonym", "evidence": [ { "id": "NP_573020", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573020" } ] }, { "name": "DEAD box protein 46", "type": "synonym", "evidence": [ { "id": "Q9VXW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXW2/entry#names_and_taxonomy" } ] }, { "name": "Prp5-PA", "type": "synonym", "evidence": [ { "id": "NP_573020", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573020" } ] }, { "name": "pre-mRNA processing factor 5", "type": "synonym", "evidence": [ { "id": "NP_573020", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573020" } ] } ], "function": [ { "annotation": "Component of the 17S U2 SnRNP complex of the spliceosome, a large ribonucleoprotein complex that removes introns from transcribed pre-mRNAs. The 17S U2 SnRNP complex (1) directly participates in early spliceosome assembly and (2) mediates recognition of the intron branch site during pre-mRNA splicing by promoting the selection of the pre-mRNA branch-site adenosine, the nucleophile for the first step of splicing. Within the 17S U2 SnRNP complex, DDX46 plays essential roles during assembly of pre-spliceosome and proofreading of the branch site.", "evidence": [ { "database": "UniProtKB", "id": "Q9VXW2", "url": "https://www.uniprot.org/uniprotkb/Q9VXW2#function" }, { "database": "UniProtKB", "id": "ARBA00049949", "url": "https://www.uniprot.org/uniprotkb/ARBA00049949#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VXW2", "url": "https://www.uniprot.org/uniprotkb/Q9VXW2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Prp5", "url": "https://www.uniprot.org/uniprotkb/Q9VXW2", "locus": { "chromosome": "X", "start_pos": 15350021, "end_pos": 15345169, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0030631", 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Classification" ] }, { "id": "IPR056149", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056149", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG6227", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG6227", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NAEMSME", "url": "https://omabrowser.org/oma/group/NAEMSME/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VXW2", "url": "https://www.orthodb.org/?gene=Q9VXW2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47958", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47958", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00270", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00270", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23469", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23469", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-72163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-9770562", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9770562", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-9943411", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9943411", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_573020", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573020", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q9VXW2", "url": "https://www.uniprot.org/uniprotkb/Q9VXW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VXW2-1", "url": "https://www.uniprot.org/uniprotkb/Q9VXW2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSKSSGRDRDRERDRERERERDRERERDRDRERDNRHDSRSRDYDMGKSRNGGGGGAGGGSRNMREDRKRGKDMISDRGKRDDKRRKCSRSKDYEKDNSPHYRRLDKDRDRDRDRDRQREKEREREKEKEREKEKERERDKDRERDRQREKESDSRRAAAAAPLIIPLLSTSCSEEEVEEIDKEEQQRRLEQEMIKRRERIERWRAERKRDTKAAVVAPSLVNSAKKWSLEDESEEDDSNPAPPLDSGKKDAEPDSPPSKFHSIRKRFDDDVVESKFSPVKRPTFSKSFGKLGIGLATKAEADIKKEPPPVDTKKEIKKKPEPVAAKMEIVEEPTVAAGEKTKKEPEQPHVGAKSEPEVEDKPQPEAEPEDEIDPLDAYMQEVNNEMRRVNNFVNPPAKSQGVVILTGVAKKKTTTLKKGEVIEQNMDSLEYSSEDELEDIRDTAVNLAMKHRKELAKIDHSSVTYAPFRKNFYVEVPELTRMTAADVEKYRSDLEGIQVKGKGCPKPIKTWAQCGVSKKEMEVLRRLGFEKPTPIQCQAIPAIMSGRDLIGIAKTGSGKTLAFILPMFRHILDQPSMEDGDGAIAIIMAPTRELCMQIGKDIRKFSKSLGLRPVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIIDNVRPDRQTVMFSATFPRQMEALARRILKKPIEVIVGGRSVVCKEVEQHVVILNDDAKFFKLLELLGIYQEAGSIIVFVDKQENADILLRDLMKASYPCMSLHGGIDQFDRDSTIIDFKSGKVRLLIATSVAARGLDVKDLILVVNYDVPNHYEDYVHRCGRTGRAGKKGSAYTFITPEQSRYAGDIIRAMDLSGTLIPAELQALWTEYKALQEAEGKTVHTGGGFSGKGFKFDEQEFNAAKESKKLQKAALGLADSDDEEDIEQDIDQQIEQIFAAKRTVKDTSAAATAAAAAAAAAAAAAAAVSGANPALASAAAQAAAAAAAANIAIAAASAPAAAGGAPSVAMGGALSSDKLELAKRLASKINSSKNLDTKGSVVTVEPMIKGPHVTGAAATLLTARTVAEQMAAKLNNKLNYQPKEDEEGLGPLVGGTTNPFTKYEEELEINDFPQQARWKVTSKEALAQISEYSEAGLTVRGTYVPQGKNPPDGERKLYLAIESCSELAVQKAKREITRLIKEELLKLSSAHHVFNKGRYKVV", "length": 1224, "header": "tr|Q9VXW2-1|Q9VXW2_DROME Isoform 1 of Probable ATP-dependent RNA helicase DDX46 OS=Drosophila melanogaster OX=7227 GN=Prp5 PE=1 SV=1 CANONICAL=Q9VXW2-1" }, "isoforms": [ { "isoform_ac": "Q9VXW2-1", "url": "https://www.uniprot.org/uniprotkb/Q9VXW2/entry#Q9VXW2-1", "sequence": { "sequence": "MSKSSGRDRDRERDRERERERDRERERDRDRERDNRHDSRSRDYDMGKSRNGGGGGAGGGSRNMREDRKRGKDMISDRGKRDDKRRKCSRSKDYEKDNSPHYRRLDKDRDRDRDRDRQREKEREREKEKEREKEKERERDKDRERDRQREKESDSRRAAAAAPLIIPLLSTSCSEEEVEEIDKEEQQRRLEQEMIKRRERIERWRAERKRDTKAAVVAPSLVNSAKKWSLEDESEEDDSNPAPPLDSGKKDAEPDSPPSKFHSIRKRFDDDVVESKFSPVKRPTFSKSFGKLGIGLATKAEADIKKEPPPVDTKKEIKKKPEPVAAKMEIVEEPTVAAGEKTKKEPEQPHVGAKSEPEVEDKPQPEAEPEDEIDPLDAYMQEVNNEMRRVNNFVNPPAKSQGVVILTGVAKKKTTTLKKGEVIEQNMDSLEYSSEDELEDIRDTAVNLAMKHRKELAKIDHSSVTYAPFRKNFYVEVPELTRMTAADVEKYRSDLEGIQVKGKGCPKPIKTWAQCGVSKKEMEVLRRLGFEKPTPIQCQAIPAIMSGRDLIGIAKTGSGKTLAFILPMFRHILDQPSMEDGDGAIAIIMAPTRELCMQIGKDIRKFSKSLGLRPVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIIDNVRPDRQTVMFSATFPRQMEALARRILKKPIEVIVGGRSVVCKEVEQHVVILNDDAKFFKLLELLGIYQEAGSIIVFVDKQENADILLRDLMKASYPCMSLHGGIDQFDRDSTIIDFKSGKVRLLIATSVAARGLDVKDLILVVNYDVPNHYEDYVHRCGRTGRAGKKGSAYTFITPEQSRYAGDIIRAMDLSGTLIPAELQALWTEYKALQEAEGKTVHTGGGFSGKGFKFDEQEFNAAKESKKLQKAALGLADSDDEEDIEQDIDQQIEQIFAAKRTVKDTSAAATAAAAAAAAAAAAAAAVSGANPALASAAAQAAAAAAAANIAIAAASAPAAAGGAPSVAMGGALSSDKLELAKRLASKINSSKNLDTKGSVVTVEPMIKGPHVTGAAATLLTARTVAEQMAAKLNNKLNYQPKEDEEGLGPLVGGTTNPFTKYEEELEINDFPQQARWKVTSKEALAQISEYSEAGLTVRGTYVPQGKNPPDGERKLYLAIESCSELAVQKAKREITRLIKEELLKLSSAHHVFNKGRYKVV", "length": 1224, "header": "tr|Q9VXW2-1|Q9VXW2_DROME Isoform 1 of Probable ATP-dependent RNA helicase DDX46 OS=Drosophila melanogaster OX=7227 GN=Prp5 PE=1 SV=1 CANONICAL=Q9VXW2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VXW2", "url": "https://www.uniprot.org/uniprotkb/Q9VXW2" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VXW2", "url": "https://www.uniprot.org/uniprotkb/Q9VXW2" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXW2", "url": "https://www.uniprot.org/uniprotkb/Q9VXW2" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXW2", "url": "https://www.uniprot.org/uniprotkb/Q9VXW2" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VXW2", "url": "https://www.uniprot.org/uniprotkb/Q9VXW2" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VXW2", "url": "https://www.uniprot.org/uniprotkb/Q9VXW2" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VXW2", "url": "https://www.uniprot.org/uniprotkb/Q9VXW2" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXW2", "url": "https://www.uniprot.org/uniprotkb/Q9VXW2" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXW2", "url": "https://www.uniprot.org/uniprotkb/Q9VXW2" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VXW2", "url": "https://www.uniprot.org/uniprotkb/Q9VXW2" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VXW2", "url": "https://www.uniprot.org/uniprotkb/Q9VXW2" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG6227", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG6227", "resource": "KEGG Pathway" }, { "id": "R-DME-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" }, { "id": "R-DME-9770562", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9770562", "resource": "Reactome", "description": "mRNA Polyadenylation" }, { "id": "R-DME-9943411", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9943411", "resource": "Reactome", "description": "CHD1 and CHD2 subfamily" } ], "orthologs": [ { "uniprot_canonical_ac": "P21372-1", "protein_name": "Pre-mRNA-processing ATP-dependent RNA helicase PRP5", "gene_name": "PRP5", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "METIDSKQNINRESLLEERRKKLAKWKQKKAQFDAQKEHQTSRNDIVTNSLEGKQTTEKFTERQERVKEELRKRKNEFRKSDEPVSVKPSKKKSKRSKVKKKISFDFSDDDDSEIGVSFRSKEHIQKAPEHDNEKDPLDEFMTSLKEEKMSNSKGMYDRGDILDVEDQLFELGGTDDEDVEDNTDNSNIAKIAKLKAKKRVKQIYYSPEELEPFQKNFYIESETVSSMSEMEVEELRLSLDNIKIKGTGCPKPVTKWSQLGLSTDTMVLITEKLHFGSLTPIQSQALPAIMSGRDVIGISKTGSGKTISYLLPLLRQVKAQRPLSKHETGPMGLILAPTRELALQIHEEVTKFTEADTSIRSVCCTGGSEMKKQITDLKRGTEIVVATPGRFIDILTLNDGKLLSTKRITFVVMDEADRLFDLGFEPQITQIMKTVRPDKQCVLFSATFPNKLRSFAVRVLHSPISITINSKGMVNENVKQKFRICHSEDEKFDNLVQLIHERSEFFDEVQSENDGQSSDVEEVDAKAIIFVSSQNICDFISKKLLNAGIVTCAIHAGKPYQERLMNLEKFKREKNSILLCTEVLSRGLNVPEVSLVIIYNAVKTFAQYVHTTGRTARGSRSGTAITLLLHDELSGAYILSKAMRDEEIKALDPLQAKELQEMSAKFESGMKKGKFRLSKGFGGKGLENIKSKREEAQNKDLELKKNDKRSDDLEKKISNPREGHDSVSESSALIPRLNYELFKESTDGSIIFYAKVYINDLPQIVRWEATKNTTLLFIKHETGCSITNKGKFYPEGKEPKNENDEPKLYLLIEGQDEKDIQLSIELLEQKVKEGVVKAASLSLKSTKY", "length": 849 }, "evidence": [ { "id": "MGI:1920895", "url": "https://alliancegenome.org/gene/MGI:1920895#orthology", "database": "AGR" }, { "id": "HGNC:18681", "url": "https://alliancegenome.org/gene/HGNC:18681#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-667", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-667#orthology", "database": "AGR" }, { "id": "RGD:708480", "url": "https://alliancegenome.org/gene/RGD:708480#orthology", "database": "AGR" }, { "id": "FB:FBgn0030631", "url": "https://alliancegenome.org/gene/FB:FBgn0030631#orthology", "database": "AGR" }, { "id": "SGD:S000000441", "url": "https://alliancegenome.org/gene/SGD:S000000441#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q4TVV3-1", "protein_name": "Probable ATP-dependent RNA helicase DDX46", "gene_name": "ddx46", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGRESRHYRKRSSSRGRSGSLSKSRSPDSKRSKKDDRTASRTHSRRERSRSRERRRSRERKRQRRSSRDRRRSRSRERRRSKSRSRGRSKEKPENGDQTADKKKIKEEKEEEKPEDQDFDQNTLEEEMRKRKERVEKWREEQRKTAMENIGEIKKELEEMKQGKKWSLEDDDEEQDKAAEAEESERMEEEEVGEEVDPLDAYMEEVKEEVKKFNMGTMKGANDKKGGMSVTKVVTVVKTKKMPHATKKKGELMENDQDAMEYSSEEEEVDLQTALTGFQTKQRKVLEPVDHQKIQYEPFRKNFYVEVPELARMSPEEVSEYRLELEGISVKGKGCPKPIKTWVQCGISMKVLNALKKHNYEKPTPIQAQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHILDQRPVGEAEGPLAVIMTPTRELALQITKECKKFSKSLALRVVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLGANNGRVTNLRRVTYVVIDEADRMFDMGFEPQVMRIVDNVRPDRQTVMFSATFPRTMEALARRILSKPVEVQVGGRSVVCSDVEQHVIVIEEEKKFLKLLEILGHYQEKGSVIIFVDKQEHADGLLKDLMKASYPCMSLHGGIDQYDRDSIINDFKNGACRLLVATSVAARGLDVKQLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEGQARYSGDILKALELSGSSVPAELEQLWTNFKEQQKAEGKIIKSSSGFSGKGFKFDETEHALANERKKLQKWALGLHDSDDEDTALDIDEQIESMFNSKKRVKDFSAPGSVSAGSAGGVSGSVSAVSGLGSLSTPSAGNIQKLEIAKKLALRIQAQKNLGAEAQDVMQQATNAILRGGTIIAPSVSAKTIAEQQAEKINAKLNYTPVEKLEEERQAAEAAETVKRYEEELEINDFPQTARWKVTSKEALQRIGEYSEAAITIRGTYFPPGKEPKEGERKIYLAIESANELAVQKAKAEITRLIKEELIRLQNSYQPTSKGRYKVL", "length": 1018 }, "evidence": [ { "id": "MGI:1920895", "url": "https://alliancegenome.org/gene/MGI:1920895#orthology", "database": "AGR" }, { "id": "HGNC:18681", "url": "https://alliancegenome.org/gene/HGNC:18681#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-667", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-667#orthology", "database": "AGR" }, { "id": "RGD:708480", "url": "https://alliancegenome.org/gene/RGD:708480#orthology", "database": "AGR" }, { "id": "FB:FBgn0030631", "url": "https://alliancegenome.org/gene/FB:FBgn0030631#orthology", "database": "AGR" }, { "id": "SGD:S000000441", "url": "https://alliancegenome.org/gene/SGD:S000000441#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q569Z5-1", "protein_name": "Probable ATP-dependent RNA helicase DDX46", "gene_name": "Ddx46", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGRESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGSKTKKTENRSRSKEKAEGGDSSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKKAMENIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEGTEMEDEELDPLDAYMEEVKEEVKKFNMRSVKGGAGNEKKSGPTVTKVVTVVTTKKAVVDADKKKGELMENDQDAMEYSSEEEEVDLQTALTGYQTKQRKLLEPVDHGKIEYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGITVKGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVRPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLELLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIKALELSGTAVPPDLEKLWSDFKDQQKAEGKIIKKSSGFSGKGFKFDETEQALANERKKLQKAALGLQDSDDEDAAVDIDEQIESMFNSKKRVKDMAAPGTSSVPAPTAGNAEKLEIAKRLALRINAQKNLGIESQVDVMQQATNAILRGGTILAPTVSAKTIAEQLAEKINAKLNYVPLEKQEEERQEGGQSESFKRYEEELEINDFPQTARWKVTSKEALQRISEYSEAAITIRGTYFPPGKEPKEGERKIYLAIESANELAVQKAKAEITRLIKEELIRLQNSYQPTNKGRYKVL", "length": 1032 }, "evidence": [ { "id": "MGI:1920895", "url": "https://alliancegenome.org/gene/MGI:1920895#orthology", "database": "AGR" }, { "id": "HGNC:18681", "url": "https://alliancegenome.org/gene/HGNC:18681#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-667", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-667#orthology", "database": "AGR" }, { "id": "RGD:708480", "url": "https://alliancegenome.org/gene/RGD:708480#orthology", "database": "AGR" }, { "id": "FB:FBgn0030631", "url": "https://alliancegenome.org/gene/FB:FBgn0030631#orthology", "database": "AGR" }, { "id": "SGD:S000000441", "url": "https://alliancegenome.org/gene/SGD:S000000441#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q62780-1", "protein_name": "Probable ATP-dependent RNA helicase DDX46", "gene_name": "Ddx46", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGSKSKKAENRSRSKEKAEGGDSSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKKAMENIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEGNEMEDEELDPLDAYMEEVKEEVKKFNMRSVKGGAGNEKKSGPTVTKVVTVVTTKKAVVDADKKKGELMENDQDAMEYSSEEEEVDLQTALTGYQTKQRKLLEPVDHGKIEYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGITVKGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVRPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLELLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIKALELSGTAVPPDLEKLWSDFKDQQKAEGKIIKKSSGFSGKGFKFDETEQALANERKKLQKAALGLQDSDDEDAAVDIDEQIESMFNSKKRVKDMAAPGTSSAPAPTAGNAEKLEIAKRLALRINAQKNLGIESQVDVMQQATNAILRGGPLLAPTVSAKTIAEQLAEKINAKLNYVPLEKQEEERQEGGQSESFKRYEEELEINDFPQTARWKVTSKEALQRISEYSEAAITIRGTYFPPGKEPKEGERKIYLAIESANELAVQKAKAEITRLIKEELIRLQNSYQPTNKGRYKVL", "length": 1032 }, "evidence": [ { "id": "MGI:1920895", "url": "https://alliancegenome.org/gene/MGI:1920895#orthology", "database": "AGR" }, { "id": "HGNC:18681", "url": "https://alliancegenome.org/gene/HGNC:18681#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-667", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-667#orthology", "database": "AGR" }, { "id": "RGD:708480", "url": "https://alliancegenome.org/gene/RGD:708480#orthology", "database": "AGR" }, { "id": "FB:FBgn0030631", "url": "https://alliancegenome.org/gene/FB:FBgn0030631#orthology", "database": "AGR" }, { "id": "SGD:S000000441", "url": "https://alliancegenome.org/gene/SGD:S000000441#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7L014-1", "protein_name": "Probable ATP-dependent RNA helicase DDX46", "gene_name": "DDX46", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGRESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKKAMENIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEGNEMEGEELDPLDAYMEEVKEEVKKFNMRSVKGGGGNEKKSGPTVTKVVTVVTTKKAVVDSDKKKGELMENDQDAMEYSSEEEEVDLQTALTGYQTKQRKLLEPVDHGKIEYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGITVKGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVRPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLELLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIKALELSGTAVPPDLEKLWSDFKDQQKAEGKIIKKSSGFSGKGFKFDETEQALANERKKLQKAALGLQDSDDEDAAVDIDEQIESMFNSKKRVKDMAAPGTSSVPAPTAGNAEKLEIAKRLALRINAQKNLGIESQDVMQQATNAILRGGTILAPTVSAKTIAEQLAEKINAKLNYVPLEKQEEERQDGGQNESFKRYEEELEINDFPQTARWKVTSKEALQRISEYSEAAITIRGTYFPPGKEPKEGERKIYLAIESANELAVQKAKAEITRLIKEELIRLQNSYQPTNKGRYKVL", "length": 1031 }, "evidence": [ { "id": "MGI:1920895", "url": "https://alliancegenome.org/gene/MGI:1920895#orthology", "database": "AGR" }, { "id": "HGNC:18681", "url": "https://alliancegenome.org/gene/HGNC:18681#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-667", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-667#orthology", "database": "AGR" }, { "id": "RGD:708480", "url": "https://alliancegenome.org/gene/RGD:708480#orthology", "database": "AGR" }, { "id": "FB:FBgn0030631", "url": "https://alliancegenome.org/gene/FB:FBgn0030631#orthology", "database": "AGR" }, { "id": "SGD:S000000441", "url": "https://alliancegenome.org/gene/SGD:S000000441#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9SF41-1", "protein_name": "DEAD-box ATP-dependent RNA helicase 45", "gene_name": "RH45", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MLEKSKSRKENDRKDRDRSKKENGRRDTTEMRSRVKRCDSEEEERIRIRRDRKSSDFEEEEYERDSKRRGEDKGRGRRERDRDRGKYLKRDRERREREKEKGRKKQKKERSREDCNEESDDVKCGLKRKRTERSRHGDDDVEKKTRDEQVEDEQKQLAEEVEKRRRRVQEWQELKRQNEEAQIESKGPETGKAWTLDGESDDEVKSDSEMDVDRDTKLENGGDAKMVASENETAVTVSENGGDRAADEDEIDPLDAFMNTMVLPEVEKLSNIVIDGILDFKMNGKETGDQAKKGFNKAALGRIIQGEDSDSDYSEPKSDDDPSLDEDDEEFMKRVKKTKAEKLSLVDHSKIEYEPFRKNFYIEVKDISRMTQDAVNAYRKELELKVHGKDVPRPIQFWHQTGLTSKILDTLKKLNYEKPMPIQAQALPIIMSGRDCIGVAKTGSGKTLGFVLPMLRHIKDQPPVEAGDGPIGLVMAPTRELVQQIYSDIRKFSKALGIICVPVYGGSGVAQQISELKRGTEIVVCTPGRMIDILCTSSGKITNLRRVTYLVMDEADRMFDMGFEPQITRIVQNIRPDRQTVLFSATFPRQVETLARKVLNKPVEIQVGGRSVVNKDITQLVEIRPESERFSRLLELLGEWYEKGKVLVFVRSQEKSISDFKSDVCNLLIATSVAARGLDVKELELVVNFDAPNHYEDYVHRVGRTGRAGRKGCAVTFISEDDAKYAPDLVKALELSEQPVPDDVKAVAEGFMAKVKQGIEQAHGTGYGGSGFKFNEEEDEVRKAAKKAQAKEYGFEEEKSDSEDENDVVRKAGGDISQQQITLAQIAAIASAASKAPVTANQLLPNGGGLATEPGIPPTDGAGRVAAMIAAANVQQYLAKIQADAIPEHYEAELEINDFPQNARWKVTHKETLGPISEWSGASITTRGKFYEAGRIPGPEERKLYLFVEGPTEISVKTAKAELKRVLEDITNQTFSLPGGAQSGRYSVL", "length": 989 }, "evidence": [ { "id": "Q9VXW2", "url": "https://omabrowser.org/oma/group/Q9VXW2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VXW2", "url": "https://www.uniprot.org/uniprotkb/Q9VXW2" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "Q9VXW2", "url": "https://www.uniprot.org/uniprotkb/Q9VXW2" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "Q9VXW2", "url": "https://www.uniprot.org/uniprotkb/Q9VXW2" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "Q9VXW2", "url": "https://www.uniprot.org/uniprotkb/Q9VXW2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VXW2", "url": "https://www.uniprot.org/uniprotkb/Q9VXW2" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "Q9VXW2", "url": "https://www.uniprot.org/uniprotkb/Q9VXW2" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "Q9VXW2", "url": "https://www.uniprot.org/uniprotkb/Q9VXW2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "Q9VXW2", "url": "https://www.uniprot.org/uniprotkb/Q9VXW2" } ], "pmid": "" }, { "name": "regulation of alternative mRNA splicing, via spliceosome", "id": "GO:0000381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000381", "evidence": [ { "database": "UniProtKB", "id": "Q9VXW2", "url": "https://www.uniprot.org/uniprotkb/Q9VXW2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1052, "end_pos": 1054, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O46072-1", "P23128-1", "P26802-1", "Q02748-1", "Q26454-1", "Q9VD51-1", "Q9VNP5-1", "Q9W3Y5-1", "Q7KN62-1", "Q9VF26-1", "Q9VL52-1", "Q07886-1", "Q23976-1", "Q27268-1", "Q9V3C0-1", "Q9VHP0-1", "Q9VHU1-1", "P49735-1", "Q9V461-1", "Q9VGW6-1", "P19109-1", "P29844-1", "Q9VDY1-1", "O61305-2", "Q7K3M5-1", "P09052-1", "A1Z9L3-1", "Q9VN03-1", "Q9VHS8-1", "Q9VUV9-1", "Q9XYU0-1", "Q9XYU1-1", "Q9VIF6-1", "Q9VVK8-1", "Q9VRI0-1", "Q9VJ74-1", "Q9VTC1-1", "Q9VX34-1", "Q9VXW2-1", "Q9W3M7-1", "Q9V3K3-1", "Q9VH07-1", "Q9V3C4-1", "P46461-1", "P54351-1", "Q86B47-1", "Q9I7M8-1", "P24785-1", "A8DZ26-1", "Q9VQN8-1", "Q9VNV3-1", "Q8IRL9-1", "P10987-1", "P10981-1", "P20480-1", "Q9VL25-1", "P53501-1", "Q8ING5-1", "Q6J5K9-1", "P02572-1", "P83967-1", "P02574-1", "Q9VL76-1", "Q9VDA0-1", "Q9W4W2-1", "Q9VIZ3-1", "Q9VY54-1", "Q9VR29-1", "Q7JYV7-1", "Q9VGI8-1", "Q02870-1", "Q9W252-1", "Q9W484-1", "O16102-1", "Q9VSE2-1", "Q9VSE6-1", "Q7KVP9-1", "Q7KU24-1", "Q7KSN8-1", "O97159-1", "Q9VZ55-1", "Q9GQN5-1", "Q9VCH8-1", "Q9XZS9-1", "Q9VQR3-1", "Q9VTL5-1", "Q9VYS3-1", "Q9VL72-1", "Q9VF30-1", "O76460-1", "P25439-1", "Q9VF56-1" ], "evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] }, { "id": "R-DME-9770131", "name": "Formation of the Spliceosomal B* complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [ "R-DME-156776", "R-DME-72060", "R-DME-8867884", "R-DME-8867893", "R-DME-8867898", "R-DME-8849148", "R-DME-8952113", "R-DME-9769592", "R-DME-9770419", "R-DME-9770425", "R-DME-9770427", "R-DME-9770428", "R-DME-9770430" ], "output_participant_list": [ "R-DME-2396419", "R-DME-8850837", "R-DME-8850839", "R-DME-8867885", "R-DME-9769563" ], "enzyme_list": [ "Q9VR29-1", "Q9VHS8-1", "Q9VUV9-1", "Q7KSN8-1", "P04052-1", "P08266-1", "Q9V3G3-1", "Q9XYZ6-1", "Q27268-1", "Q9VAW1-1", "Q9VTC1-1", "Q9Y134-1", "Q7K3M5-1", "Q9VIZ3-1", "Q9W0Q2-1", "Q9VXW2-1", "Q9VY54-1" ], "evidence": [ { "id": "R-DME-9770131", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9770131" } ] }, { "id": "R-DME-9770141", "name": "Formation of the Spliceosomal C* complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [ "R-DME-5688093", "R-DME-5688092", "R-DME-72073", "R-DME-9769591", "R-DME-9769593", "R-DME-9769594", "R-DME-9769596", "R-DME-9769598", "R-DME-9769599", "R-DME-9769601" ], "output_participant_list": [], "enzyme_list": [ "Q9VR29-1", "Q9VHS8-1", "Q9VUV9-1", "Q7KSN8-1", "P04052-1", "P08266-1", "Q9V3G3-1", "Q9XYZ6-1", "A1Z9L3-1", "Q27268-1", "Q9V3C0-1", "Q9VAW1-1", "Q9Y134-1", "Q7K3M5-1", "Q9W0Q2-1", "Q9VXW2-1", "Q9VY54-1" ], "evidence": [ { "id": "R-DME-9770141", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9770141" } ] }, { "id": "R-DME-9770236", "name": "Formation of the Spliceosomal P complex and exon ligation", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [ "R-DME-9769588", "R-DME-9769590", "R-DME-9769602" ], "output_participant_list": [ "R-DME-6791189", "R-DME-8849139", "R-DME-9769562" ], "enzyme_list": [ "Q9VHS8-1", "Q9VUV9-1", "Q7KSN8-1", "P04052-1", "P08266-1", "Q9V3G3-1", "Q9XYZ6-1", "A1Z9L3-1", "Q27268-1", "Q9V3C0-1", "Q9VAW1-1", "Q9Y134-1", "Q7K3M5-1", "Q9W0Q2-1", "Q9VXW2-1" ], "evidence": [ { "id": "R-DME-9770236", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9770236" } ] }, { "id": "R-DME-9794542", "name": "Formation of the Spliceosomal C complex containing intron lariat", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VR29-1", "Q9VHS8-1", "Q9VUV9-1", "Q7KSN8-1", "P04052-1", "P08266-1", "Q9V3G3-1", "Q9XYZ6-1", "Q27268-1", "Q9VAW1-1", "Q9Y134-1", "Q7K3M5-1", "Q9W0Q2-1", "Q9VXW2-1", "Q9VY54-1" ], "evidence": [ { "id": "R-DME-9794542", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9794542" } ] }, { "id": "R-DME-9943567", "name": "CHD1:H3K4me3 interacts with post-initiation transcription complexes", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q7KU24-1", "Q9VTC1-1", "Q7K3M5-1", "Q9VXW2-1" ], "evidence": [ { "id": "R-DME-9943567", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9943567" } ] }, { "id": "R-DME-9970141", "name": "Core CPA complex binds capped pre-mRNA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P04052-1", "P08266-1", "Q9VE51-1", "Q9VPT8-1", "Q9VTC1-1", "Q7K3M5-1", "P24785-1", "Q9VXW2-1" ], "evidence": [ { "id": "R-DME-9970141", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9970141" } ] }, { "id": "R-DME-9970189", "name": "PABPN1-stimulated PAPOL synthesizes polyA tail at distal 3'UTR PAS", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [ "R-DME-72008" ], "output_participant_list": [], "enzyme_list": [ "Q9W2A5-1", "P48462-1", "Q05547-1", "P04052-1", "P08266-1", "P11612-1", "P12982-1", "P48461-1", "Q9VE51-1", "Q9VPT8-1", "Q9VQL9-1", "A0A0B4KG96-1", "Q9VTC1-1", "Q7KVM5-1", "Q7K3M5-1", "P24785-1", "Q9VXW2-1" ], "evidence": [ { "id": "R-DME-9970189", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9970189" } ] }, { "id": "R-DME-9970190", "name": "PP1 dephosphorylates RNA Pol II", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9W2A5-1", "P48462-1", "Q05547-1", "P04052-1", "P08266-1", "P11612-1", "P12982-1", "P48461-1", "Q9VE51-1", "Q9VPT8-1", "Q9VQL9-1", "A0A0B4KG96-1", "Q9VTC1-1", "Q7KVM5-1", "Q7K3M5-1", "P24785-1", "Q9VXW2-1" ], "evidence": [ { "id": "R-DME-9970190", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9970190" } ] }, { "id": "R-DME-9970191", "name": "RBBP6 activates CPSF complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9W2A5-1", "P48462-1", "Q05547-1", "P04052-1", "P08266-1", "P11612-1", "P12982-1", "P48461-1", "Q9VE51-1", "Q9VPT8-1", "Q9VQL9-1", "A0A0B4KG96-1", "Q9VTC1-1", "Q7KVM5-1", "Q7K3M5-1", "P24785-1", "Q9VXW2-1" ], "evidence": [ { "id": "R-DME-9970191", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9970191" } ] }, { "id": "R-DME-9970318", "name": "PABPN1-stimulated PAPOL synthesizes polyA tail at proximal 3'UTR PAS", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9W2A5-1", "P48462-1", "Q05547-1", "P04052-1", "P08266-1", "P11612-1", "P12982-1", "P48461-1", "Q9VE51-1", "Q9VPT8-1", "Q9VQL9-1", "A0A0B4KG96-1", "Q9VTC1-1", "Q7KVM5-1", "Q7K3M5-1", "P24785-1", "Q9VXW2-1" ], "evidence": [ { "id": "R-DME-9970318", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9970318" } ] }, { "id": "R-DME-9970320", "name": "PABPN1-stimulated PAPOL synthesizes polyA tail at intronic PAS", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9W2A5-1", "P48462-1", "Q05547-1", "P04052-1", "P08266-1", "P11612-1", "P12982-1", "P48461-1", "Q9VE51-1", "Q9VPT8-1", "Q9VQL9-1", "A0A0B4KG96-1", "Q9VTC1-1", "Q7KVM5-1", "Q7K3M5-1", "P24785-1", "Q9VXW2-1" ], "evidence": [ { "id": "R-DME-9970320", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9970320" } ] } ], "reaction_participants": [ { "participant_id": "R-DME-156776", "participant_name": "Upf3 [nucleoplasm]", "crossref": [ { "id": "Q9W1H3", "database": "UniProt", "url": "" }, { "id": "FBgn0034923", "database": "FlyBase", "url": "" }, { "id": "NP_726375.1", "database": "RefSeq", "url": "" }, { "id": "NP_611844.3", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-DME-2396419", "participant_name": "Mfap1 [nucleoplasm]", "crossref": [ { "id": "Q9W062", "database": "UniProt", "url": "" }, { "id": "FBgn0035294", "database": "FlyBase", "url": "" }, { "id": "FBpp0072720", "database": "ENSEMBL", "url": "" }, { "id": "NP_647679.1", "database": "RefSeq", "url": "" }, { "id": "Q9W062", "database": "PRO", "url": "" }, { "id": "FBgn0035294", "database": "ENSEMBL", "url": "" }, { "id": "FBtr0072841", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-DME-5688092", "participant_name": "DHX8 [nucleoplasm]", "crossref": [ { "id": "A1Z9L3", "database": "UniProt", "url": "" }, { "id": "FBgn0086895", "database": "ENSEMBL", "url": "" }, { "id": "FBpp0086647", "database": "ENSEMBL", "url": "" }, { "id": "FBtr0087518", "database": "ENSEMBL", "url": "" }, { "id": "FBgn0086895", "database": "FlyBase", "url": "" }, { "id": "A1Z9L3", "database": "PRO", "url": "" }, { "id": "NP_610928.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-DME-5688093", "participant_name": "Prp18 [nucleoplasm]", "crossref": [ { "id": "Q9V437", "database": "UniProt", "url": "" }, { "id": "FBgn0027784", "database": "FlyBase", "url": "" }, { "id": "NP_650776.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-DME-6791189", "participant_name": "Mtr4 [nucleoplasm]", "crossref": [ { "id": "FBgn0001986", "database": "FlyBase", "url": "" }, { "id": "Q9Y134", "database": "UniProt", "url": "" }, { "id": "NP_524929.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-DME-72008", "participant_name": "Pabp2 [nucleoplasm]", "crossref": [ { "id": "Q7KNF2", "database": "UniProt", "url": "" }, { "id": "FBgn0005648", "database": "ENSEMBL", "url": "" }, { "id": "FBpp0087863", "database": "ENSEMBL", "url": "" }, { "id": "FBpp0087864", "database": "ENSEMBL", "url": "" }, { "id": "FBtr0088785", "database": "ENSEMBL", "url": "" }, { "id": "FBtr0088786", "database": "ENSEMBL", "url": "" }, { "id": "FBgn0005648", "database": "FlyBase", "url": "" }, { "id": "Q7KNF2", "database": "PRO", "url": "" }, { "id": "NP_476902.1", "database": "RefSeq", "url": "" }, { "id": "NP_724648.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-DME-72060", "participant_name": "Prp16 [nucleoplasm]", "crossref": [ { "id": "Q9VY54", "database": "UniProt", "url": "" }, { "id": "FBgn0026713", "database": "FlyBase", "url": "" }, { "id": "NP_572947.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-DME-72073", "participant_name": "Slu7 [nucleoplasm]", "crossref": [ { "id": "Q9VAQ7", "database": "UniProt", "url": "" }, { "id": "FBgn0039626", "database": "ENSEMBL", "url": "" }, { "id": "FBpp0084787", "database": "ENSEMBL", "url": "" }, { "id": "FBtr0085418", "database": "ENSEMBL", "url": "" }, { "id": "FBgn0039626", "database": "FlyBase", "url": "" }, { "id": "Q9VAQ7", "database": "PRO", "url": "" }, { "id": "NP_651659.2", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-DME-8849139", "participant_name": "DDX39B [nucleoplasm]", "crossref": [ { "id": "FBpp0078755", "database": "ENSEMBL", "url": "" }, { "id": "FBgn0014189", "database": "FlyBase", "url": "" }, { "id": "Q27268", "database": "UniProt", "url": "" }, { "id": "NP_723090.1", "database": "RefSeq", "url": "" }, { "id": "FBpp0078756", "database": "ENSEMBL", "url": "" }, { "id": "FBtr0079125", "database": "ENSEMBL", "url": "" }, { "id": "NP_723089.1", "database": "RefSeq", "url": "" }, { "id": "FBtr0079124", "database": "ENSEMBL", "url": "" }, { "id": "FBpp0078754", "database": "ENSEMBL", "url": "" }, { "id": "NP_723091.1", "database": "RefSeq", "url": "" }, { "id": "FBgn0014189", "database": "ENSEMBL", "url": "" }, { "id": "Q27268", "database": "PRO", "url": "" }, { "id": "FBtr0079123", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-DME-8849148", "participant_name": "btz [nucleoplasm]", "crossref": [ { "id": "A0A0B4KH64", "database": "UniProt", "url": "" }, { "id": "FBgn0045862", "database": "FlyBase", "url": "" }, { "id": "NP_001263028.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-DME-8850837", "participant_name": "l(2)37Cb [nucleoplasm]", "crossref": [ { "id": "FBgn0086444", "database": "FlyBase", "url": "" }, { "id": "NP_609946.1", "database": "RefSeq", "url": "" }, { "id": "Q9VIZ3", "database": "UniProt", "url": "" }, { "id": "Q9VIZ3", "database": "PRO", "url": "" } ] }, { "participant_id": "R-DME-8850839", "participant_name": "Gpkow [nucleoplasm]", "crossref": [ { "id": "FBgn0038454", "database": "FlyBase", "url": "" }, { "id": "NP_650571.2", "database": "RefSeq", "url": "" }, { "id": "Q9VES0", "database": "UniProt", "url": "" } ] }, { "participant_id": "R-DME-8867884", "participant_name": "Syf2 [nucleoplasm]", "crossref": [ { "id": "Q9V5Q4", "database": "UniProt", "url": "" }, { "id": "FBgn0033556", "database": "ENSEMBL", "url": "" }, { "id": "FBpp0087342", "database": "ENSEMBL", "url": "" }, { "id": "FBtr0088247", "database": "ENSEMBL", "url": "" }, { "id": "FBgn0033556", "database": "FlyBase", "url": "" }, { "id": "Q9V5Q4", "database": "PRO", "url": "" }, { "id": "NP_610617.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-DME-8867885", "participant_name": "Dmel\\CG10907 [nucleoplasm]", "crossref": [ { "id": "Q9VTN7", "database": "UniProt", "url": "" }, { "id": "NP_648508.1", "database": "RefSeq", "url": "" }, { "id": "FBgn0036207", "database": "FlyBase", "url": "" } ] }, { "participant_id": "R-DME-8867893", "participant_name": "Dmel\\CG3511 [nucleoplasm]", "crossref": [ { "id": "Q960Q8", "database": "UniProt", "url": "" }, { "id": "FBgn0035027", "database": "FlyBase", "url": "" }, { "id": "NP_611935.1", "database": "RefSeq", "url": "" }, { "id": "NP_001286847.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-DME-8867898", "participant_name": "Cwc25 [nucleoplasm]", "crossref": [ { "id": "Q9VQF5", "database": "UniProt", "url": "" }, { "id": "FBgn0031452", "database": "FlyBase", "url": "" }, { "id": "NP_608705.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-DME-8952113", "participant_name": "Ppil4 [nucleoplasm]", "crossref": [ { "id": "Q9XYZ6", "database": "UniProt", "url": "" }, { "id": "FBgn0027617", "database": "FlyBase", "url": "" }, { "id": "Q9XYZ6", "database": "PRO", "url": "" }, { "id": "NP_651291.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-DME-9769562", "participant_name": "CYC4 [nucleoplasm]", "crossref": [ { "id": "FBgn0034109", "database": "FlyBase", "url": "" }, { "id": "Q7K231", "database": "UniProt", "url": "" }, { "id": "NP_611113.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-DME-9769563", "participant_name": "mdlc [nucleoplasm]", "crossref": [ { "id": "Q9VDP8", "database": "UniProt", "url": "" }, { "id": "NP_650865.1", "database": "RefSeq", "url": "" }, { "id": "FBgn0038772", "database": "FlyBase", "url": "" } ] }, { "participant_id": "R-DME-9769588", "participant_name": "Dmel\\CG7974 [nucleoplasm]", "crossref": [ { "id": "Q9W0A9", "database": "UniProt", "url": "" }, { "id": "FBgn0035254", "database": "FlyBase", "url": "" }, { "id": "NP_647643.1", "database": "RefSeq", "url": "" }, { "id": "NP_001261273.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-DME-9769590", "participant_name": "Dmel\\CG12818 [nucleoplasm]", "crossref": [ { "id": "Q9VH00", "database": "UniProt", "url": "" }, { "id": "FBgn0037809", "database": "FlyBase", "url": "" }, { "id": "Q9VH00", "database": "PRO", "url": "" }, { "id": "NP_649996.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-DME-9769591", "participant_name": "cactin [nucleoplasm]", "crossref": [ { "id": "Q9VR99", "database": "UniProt", "url": "" }, { "id": "FBgn0031114", "database": "ENSEMBL", "url": "" }, { "id": "FBpp0309346", "database": "ENSEMBL", "url": "" }, { "id": "FBtr0340400", "database": "ENSEMBL", "url": "" }, { "id": "FBgn0031114", "database": "FlyBase", "url": "" }, { "id": "Q9VR99", "database": "PRO", "url": "" }, { "id": "NP_523422.4", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-DME-9769592", "participant_name": "Moca-cyp [nucleoplasm]", "crossref": [ { "id": "Q9VAW1", "database": "UniProt", "url": "" }, { "id": "FBgn0039581", "database": "FlyBase", "url": "" }, { "id": "NP_733246.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-DME-9769593", "participant_name": "Dmel\\CG5986 [nucleoplasm]", "crossref": [ { "id": "Q9VCE2", "database": "UniProt", "url": "" }, { "id": "FBgn0043455", "database": "FlyBase", "url": "" }, { "id": "NP_001262899.1", "database": "RefSeq", "url": "" }, { "id": "NP_651207.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-DME-9769594", "participant_name": "Dmel\\CG8441 [nucleoplasm]", "crossref": [ { "id": "Q7K1V1", "database": "UniProt", "url": "" }, { "id": "FBgn0034086", "database": "FlyBase", "url": "" }, { "id": "Q7K1V1", "database": "PRO", "url": "" }, { "id": "NP_001246362.1", "database": "RefSeq", "url": "" }, { "id": "NP_611094.1", "database": "RefSeq", "url": "" } ] }, { 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXW2" }, { "id": "PRU00552", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00552" } ], "ann_type": "Motif_Annotation", "uniprotkb_annotation": "Q motif", "eco_id": "ECO_0000256", "start_pos": 510, "end_pos": 538, "start_aa": "Lys", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.6.4.13", "ec_name": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "3.6.4.13", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.13" }, { "id": "3.6.4.13", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.6.4.13" } ] } ], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1052, "end_pos": 1054 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VXW5-1", "uniprot_ac": "Q9VXW5", "uniprot_id": "Q9VXW5_DROME", "mass": { "chemical_mass": 71390.0, "monoisotopic_mass": 71390.0 }, "refseq": { "ac": "NP_573016", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573016" }, "gene_names": [ { "name": "Dmel\\CG9114", "type": "recommended", "evidence": [ { "id": "Q9VXW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXW5" } ] }, { "name": "CG9114", "type": "synonym", "evidence": [ { "id": "NP_573016", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573016" }, { "id": "Q9VXW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXW5" } ] }, { "name": "Dmel\\CG9114", "type": "synonym", "evidence": [ { "id": "NP_573016", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573016" } ] }, { "name": "Dmel_CG9114", "type": "synonym", "evidence": [ { "id": "Q9VXW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXW5" } ] } ], "protein_names": [ { "name": "CG9114-PA", "type": "synonym", "evidence": [ { "id": "NP_573016", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573016" } ] }, { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "Q9VXW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXW5/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_573016", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573016" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VXW5", "url": "https://www.uniprot.org/uniprotkb/Q9VXW5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG9114", "url": "https://www.uniprot.org/uniprotkb/Q9VXW5", "locus": { "chromosome": "X", "start_pos": 15330784, "end_pos": 15333154, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0030628", "url": "https://www.ensemblgenomes.org/id/FBgn0030628" } ] } } ], "crossref": [ { "id": "FB:FBgn0030628", "url": "https://alliancegenome.org/gene/FB:FBgn0030628", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0030628", "url": "https://bgee.org/?page=gene&gene_id=FBgn0030628", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0030628", "url": "https://flybase.org/reports/FBgn0030628", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "32460", "url": "https://www.ncbi.nlm.nih.gov/gene/32460", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dme:Dmel_CG9114", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG9114", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AQFWACQ", "url": "https://omabrowser.org/oma/group/AQFWACQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VXW5", "url": "https://www.orthodb.org/?gene=Q9VXW5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "NP_573016", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_573016", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VXW5", "url": "https://www.uniprot.org/uniprotkb/Q9VXW5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VXW5-1", "url": "https://www.uniprot.org/uniprotkb/Q9VXW5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLPFVQENVPEMLLQPARLAFCANLHVGRPRDDPTTLVLARNLKFYEFRRKDLVHYIDLKVTKLKQIATQLEAYDGPVCPFLSKQEPTDEKVDWSMLDPPEDLPLKFGKFVWQREGIYLLIQCWKHLVVLKRPKDHGANFELVADHKDVVDYQMVEGPISFQAVVELEFGNGKRQRCDFQEDFLNEEPSTSKNAGLPAKDFENLLQEVHRAQAELDSQRMQNQKELAHVQDLLYFGTPGQRSLLLEEKQPLRRLGDVWTRICGDYFVCGTLLVNITGTNRLTIVKELYPIVVIEPHTDFSVEHRLYELPLQADGQPPEDYDQLAQFWACQDQHSRRLKWRPVEKERILPPERSAAMVVSLRLVDLLEAEKLILMATYEMGEDASPRQIHLITFDVKKLLDKTESLAPTFSPATLHQDFLAVIMTHTARCSLKLEFQSAQDCTTFEQLLVSTLQFQLIQAQEANKEPTSDLLDDSEPGSHFQSSNIAADPVQRIFYNRQPQSQWCDTLLLRDDPGKHWHVYARTDDRLRLLLHRLTRDLLQLHCNLNVLEVAEHNMSPADMEMELLNSLFEEMDAWKVLSEPAASVEQRREQLTQLHKAQMASDVLASMLFTDDDDDNGA", "length": 619, "header": "tr|Q9VXW5-1|Q9VXW5_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG9114 PE=4 SV=1 CANONICAL=Q9VXW5-1" }, "isoforms": [ { "isoform_ac": "Q9VXW5-1", "url": "https://www.uniprot.org/uniprotkb/Q9VXW5/entry#Q9VXW5-1", "sequence": { "sequence": "MLPFVQENVPEMLLQPARLAFCANLHVGRPRDDPTTLVLARNLKFYEFRRKDLVHYIDLKVTKLKQIATQLEAYDGPVCPFLSKQEPTDEKVDWSMLDPPEDLPLKFGKFVWQREGIYLLIQCWKHLVVLKRPKDHGANFELVADHKDVVDYQMVEGPISFQAVVELEFGNGKRQRCDFQEDFLNEEPSTSKNAGLPAKDFENLLQEVHRAQAELDSQRMQNQKELAHVQDLLYFGTPGQRSLLLEEKQPLRRLGDVWTRICGDYFVCGTLLVNITGTNRLTIVKELYPIVVIEPHTDFSVEHRLYELPLQADGQPPEDYDQLAQFWACQDQHSRRLKWRPVEKERILPPERSAAMVVSLRLVDLLEAEKLILMATYEMGEDASPRQIHLITFDVKKLLDKTESLAPTFSPATLHQDFLAVIMTHTARCSLKLEFQSAQDCTTFEQLLVSTLQFQLIQAQEANKEPTSDLLDDSEPGSHFQSSNIAADPVQRIFYNRQPQSQWCDTLLLRDDPGKHWHVYARTDDRLRLLLHRLTRDLLQLHCNLNVLEVAEHNMSPADMEMELLNSLFEEMDAWKVLSEPAASVEQRREQLTQLHKAQMASDVLASMLFTDDDDDNGA", "length": 619, "header": "tr|Q9VXW5-1|Q9VXW5_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG9114 PE=4 SV=1 CANONICAL=Q9VXW5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VXW5", "url": "https://www.uniprot.org/uniprotkb/Q9VXW5" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VXW5", "url": "https://www.uniprot.org/uniprotkb/Q9VXW5" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXW5", "url": "https://www.uniprot.org/uniprotkb/Q9VXW5" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXW5", "url": "https://www.uniprot.org/uniprotkb/Q9VXW5" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VXW5", "url": "https://www.uniprot.org/uniprotkb/Q9VXW5" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VXW5", "url": "https://www.uniprot.org/uniprotkb/Q9VXW5" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VXW5", "url": "https://www.uniprot.org/uniprotkb/Q9VXW5" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXW5", "url": "https://www.uniprot.org/uniprotkb/Q9VXW5" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXW5", "url": "https://www.uniprot.org/uniprotkb/Q9VXW5" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VXW5", "url": "https://www.uniprot.org/uniprotkb/Q9VXW5" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VXW5", "url": "https://www.uniprot.org/uniprotkb/Q9VXW5" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], 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"https://www.ncbi.nlm.nih.gov/protein/NP_001188590", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "10732", "url": "https://www.rhea-db.org/rhea/10732", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q9VXZ8", "url": "https://www.uniprot.org/uniprotkb/Q9VXZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VXZ8-1", "url": "https://www.uniprot.org/uniprotkb/Q9VXZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNPAAQLLRMRSATAFGSAATRSITTNRRQRTTSTASAQRERTQSVSETDKFLHYSPEDGYYKTSPFDPVTIPNVPLHEYVWRDFKKWERRTAAVCVITDRQYTFAQMRDASAAFAVRLQTKFNLQKPDVLAICLPNLPEYPIATLGAIEAGLTVTTVNPVYTPDEIARQLTFSGAKFLVGTVSGFATLSQASKLVGRQIPIAVVRTSAEEALPEGAIDFSELTSTQNVRYEDLKAPKEASADDMVFLPFSSGTTGLPKGVMLSHNNITSNCEQVQASLPLDLMGPQNTLPGVLPFFHIYGLTVVMLSKLGQGCRLATMPCFKPDDFMRSLDKYQGSILNLVPPIALFMINHPKLTQETAPHLKVVMSGAAPIGQHDVERFLNKFPNTVFKQGYGMTEASPVVLLTPEGNKVYASTGVLPASTEAKIVPLDGSDAKGVGPRTTGELCVRGPQVMAGYLNNDEANQVTFYPGNWLRSGDVAFYDEDGLFYITDRMKELIKVKGFQVPPAELEAVLRDHPKILEAAVFGIPHEFNGEAPRAIVVLRQGEKASAEEISAYVAERVAHYKKLEGGVIFVDEVPKNPTGKILRRELKEKFSD", "length": 597, "header": "tr|Q9VXZ8-1|Q9VXZ8_DROME Isoform 1 of Luciferin 4-monooxygenase OS=Drosophila melanogaster OX=7227 GN=pdgy PE=1 SV=2 CANONICAL=Q9VXZ8-1" }, "isoforms": [ { "isoform_ac": "Q9VXZ8-1", "url": "https://www.uniprot.org/uniprotkb/Q9VXZ8/entry#Q9VXZ8-1", "sequence": { "sequence": "MNPAAQLLRMRSATAFGSAATRSITTNRRQRTTSTASAQRERTQSVSETDKFLHYSPEDGYYKTSPFDPVTIPNVPLHEYVWRDFKKWERRTAAVCVITDRQYTFAQMRDASAAFAVRLQTKFNLQKPDVLAICLPNLPEYPIATLGAIEAGLTVTTVNPVYTPDEIARQLTFSGAKFLVGTVSGFATLSQASKLVGRQIPIAVVRTSAEEALPEGAIDFSELTSTQNVRYEDLKAPKEASADDMVFLPFSSGTTGLPKGVMLSHNNITSNCEQVQASLPLDLMGPQNTLPGVLPFFHIYGLTVVMLSKLGQGCRLATMPCFKPDDFMRSLDKYQGSILNLVPPIALFMINHPKLTQETAPHLKVVMSGAAPIGQHDVERFLNKFPNTVFKQGYGMTEASPVVLLTPEGNKVYASTGVLPASTEAKIVPLDGSDAKGVGPRTTGELCVRGPQVMAGYLNNDEANQVTFYPGNWLRSGDVAFYDEDGLFYITDRMKELIKVKGFQVPPAELEAVLRDHPKILEAAVFGIPHEFNGEAPRAIVVLRQGEKASAEEISAYVAERVAHYKKLEGGVIFVDEVPKNPTGKILRRELKEKFSD", "length": 597, "header": "tr|Q9VXZ8-1|Q9VXZ8_DROME Isoform 1 of Luciferin 4-monooxygenase OS=Drosophila melanogaster OX=7227 GN=pdgy PE=1 SV=2 CANONICAL=Q9VXZ8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VXZ8", "url": "https://www.uniprot.org/uniprotkb/Q9VXZ8" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VXZ8", "url": "https://www.uniprot.org/uniprotkb/Q9VXZ8" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXZ8", "url": "https://www.uniprot.org/uniprotkb/Q9VXZ8" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXZ8", "url": "https://www.uniprot.org/uniprotkb/Q9VXZ8" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VXZ8", "url": "https://www.uniprot.org/uniprotkb/Q9VXZ8" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VXZ8", "url": "https://www.uniprot.org/uniprotkb/Q9VXZ8" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VXZ8", "url": "https://www.uniprot.org/uniprotkb/Q9VXZ8" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXZ8", "url": "https://www.uniprot.org/uniprotkb/Q9VXZ8" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VXZ8", "url": "https://www.uniprot.org/uniprotkb/Q9VXZ8" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VXZ8", "url": "https://www.uniprot.org/uniprotkb/Q9VXZ8" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VXZ8", "url": "https://www.uniprot.org/uniprotkb/Q9VXZ8" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG9009", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG9009", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1NBM6-1", "protein_name": "long-chain-fatty-acid--CoA ligase", "gene_name": "slc27a6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLSWIAALLTGILTAHLAQRLCFPYFWKDALYLMKVIRYGARLEIYKRTSLIVTIVDRFVQQAQRFPEKPFVIFEGVTYTYGDLEARSNRVARLFQDTVKKGDTVALLMNNEPDFISVWFGFCKLGCALAFLNTNIKSRSLLHCFNCCGAKQLVVGADLLDNLEDILPSLQEDNITVWSLGHGNSHPGVHSLLDKIEKSSQEPIAAKRRSISCLKTPTLYIFTSGTTGLPKAAVITHLQSLKAAGGFWAYGGTEKDVIYTPLPLYHSAASLVGIGGTIELGATCILKKKFSASQFWNDCRKYNVTIFQYIGELCRYLCNQPMGENEKDHKVHMGVGNGLRQDVWREFLQRFGEIRMCEIYGSTEGNLCFMNHIGKIGAVGRSNFFYKLIFKYDLVKYDLLRDEPVRDHNGFCQRVQKGETGLLLSKICSQSPFFGYAGSKQLTEKKILRDVFVKGDAYFNTGDLMAEDENNFISFKDRVGDTFRWKGENVATTEVTEILGLVDFIQEASVYGVQVPGNEGRAGMAAVIVRPECTFDGKKLFDLVVRELPSYARPLFIRLQESIETTSTFKHQKFGLVESGFNPSTISDPLYFLDYTEKSYIPLTSSIYASISNGQKKV", "length": 618 }, "evidence": [ { "id": "MGI:3036230", "url": "https://alliancegenome.org/gene/MGI:3036230#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZJA9-1", "protein_name": "long-chain-fatty-acid--CoA ligase", "gene_name": "Slc27a3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALLLLLPLLLLLPLLLKLDLWPQLRWLRADLAFTVRALRCKRALRARALAAAAADPESPEGGCSLAWRLAHLAREQPTRTFLIYGARCFSYAEAESESNRIARAFLRARGWTAGGRGSGRGSTEEDARVAPAAGDPAAGGTTAPPLAPGATVALLLPAGPEFLWLWFGLAKAGLRTAFVPSALRRGPLLHCLRSCGASAVVLATEFLESLEPDLPALRAMGLHLWATGPGTNLAGISNLLSEAATQVDEPVPGYLSAPQNIMDTCLYIFTSGTTGLPKAARVSHLKVLQCQGFYQLCGVHQEDVIYLALPLYHMSGSLLGIVGCLGIGATVVLKPKFSASQFWEDCQRHGVTVFQYIGELCRYLVNQPPSKAECGHKVRLAVGSGLRPDTWDRFVRRFGPLQILETYGATEGNVATFNYTGQQGAVGRASWLYKHIFPFSLIRYDVMTGEPIRNAQGHCMAASPGEPGLLVAPVSQESPFLGYAGAPELAQEKLLKDVFRPGDIFFNTGDLLVCDEQGFLHFHDRTGDTFRWKGENVATTEVAEVLEALDFLQEVNIYGVTVPGHEGRAGMAALALRPPQALDLVQLYTHVSENLPPYARPRFLRLQESLATTETFKQQKVRMANEGFDPSALSDPLYVLDQDKGAYLPLTPARYNALLSGDLRI", "length": 667 }, "evidence": [ { "id": "MGI:1347358", "url": "https://alliancegenome.org/gene/MGI:1347358#orthology", "database": "AGR" }, { "id": "RGD:1310605", "url": "https://alliancegenome.org/gene/RGD:1310605#orthology", "database": "AGR" }, { "id": "FB:FBgn0027601", "url": "https://alliancegenome.org/gene/FB:FBgn0027601#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZUX7-1", "protein_name": "Malonate--CoA ligase ACSF3, mitochondrial", "gene_name": "Acsf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRMSRNARLRNPLLRLCMRGHIRPTDTFRLRTFLGVGLIPARPTHLADLSRAPPLVTLRLTPGEGVAENKKAGVEPCQWFVGVMSPHLTLPFRRLIWSLASSRLTARRHRGHSLLHTAPEARTDGSAPVFIRALAFGDRVALIDKHGRHTYRELYDRSLCLAQEICSLRGCKVGDLQEERVSFLCSNDVSYVIAQWASWMSGGVAVPLYRKHPEAQLEYFIQDSRSSVVVVGQEYLERLSPLAQRLGVPLLPLTPAVYHGAAEKPIEQPIQEREWRDRGAMIFYTSGTTGRPKGALSTHRNLAAVVTGLVHSWAWTKNDVILHVLPLHHVHGVVNKLLCPLWVGATCVMLPEFSAQQVWEKFLSSEAPQINMFMAVPTIYSKLLDYYDRHFTQSHVQDFVRAVCKERIRLMVSGSAALPVPLLEKWKSATGHTLLERYGMTEIGMALSNPLTEARVPGSVGTPLPGVEVRIVSENPQKGSSYTIHAEGNMRGTKVTPGFEEKEGELLVKGPSVFQEYWDKPEETKSAFTPDGWFRTGDTAVFKDDRYWIRGRTSVDIIKTGGYKVSALEIERHLLAHPSITDVAVIGVPDMTWGQRVTAVVALQEGHSLSHRDLKEWARGVLAPYAVPSELLLVEAIPRNQMGKVNKKQLLQQFYPSEQRSHPGQG", "length": 666 }, "evidence": [ { "id": "SGD:S000000426", "url": "https://alliancegenome.org/gene/SGD:S000000426#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A2B8-1", "protein_name": "Long-chain-fatty-acid--CoA ligase", "gene_name": "Slc27a6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLLSWLTGFGAGLLSLHFVQKLLFPYFWDDLWFLLKLVRYGIQMEIYKLRGELVTVLDKFLSHARRQPKKAFIIYEGDVYTYEDVDKRSNRVAHALLNHSDLKRGDVVALLMSNEPDFVHVWFGLAKLGCVVAFLNSNLRFESLLHCIRTSEPKAMVVGEDLLGSLEEILPSLPKHIRVWGMKDSVPEGIVSLKEKLSLASDEPVPPSHHVTSSLKSTCLYIFTSGTTGLPKAAVISQFQVLKGSFGLWAFGCTADDIVYITLPLYHSSGALLGIGGCVELGATCVLKKKFSASQFWNDCRKYNVTVFQYIGELCRYLCKQPQREGEKDHRVRLAVGNGMSSDVWRQFLDRFGNIKMCEFYGATEGNICFMNHTGKIGSVGRVNFFYNLLFSFELIKYDFQKDEPLRNEQGWCYCVRKGEPGLLVSRVNKKNPFFGYTGSYKQTKSKLLFDVFKKGDVYFNTGDLMFQDHENFLYFWDRIGDTFRWKGENVATTEVANVLGRLDFIQEANVYGVPVPGYEGKAGMTSIILKPNKSLDLEKMYDQVVTSLPAYACPRFLRIQDKMETTGTFKLKKLQLVEEGFNPLKIADPLYFMDNLKKSYVPLTQEIYNQVMLEELKL", "length": 619 }, "evidence": [ { "id": "MGI:3036230", "url": "https://alliancegenome.org/gene/MGI:3036230#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9Q9W4-1", "protein_name": "Long-chain fatty acid transport protein 6", "gene_name": "Slc27a6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLSWLTGLGAGLLSLHFLQKLLFPYFWDDFWYLLKVVRYGIQMEMYKLRGELVTVLDKFLSHTRKQPRKAFIIYEGDVYTYEDVDKRSNRIAHALLNHSSLKRGDVVALLMSNEPDFVHVWFGLAKLGCVVAFLNSNLRFDSLLHCINTCEPTAVVVGGDLLGSIEEILPSLPKHVRVWGMKDSVPEGIDSLQEKLSLASDEPVPPSHHVTSSLKSTCLYIFTSGTTGLPKAAVISQLQVLKGSVGLWAFGCTADDIIYITLPLYHSSGSLLGIGGCVELGATCVLKKKFSASQFWNDCKKYNVTVFQYIGELCRYLCKQPQREGEKDHRVRLAVGNGLSSDVWRQFLDRFGNIKMCELYGATEGNIVFMNHTGKIGSVGRANFFYSLFFSFELIKYDFQKDEPWRNGQGWCSCVRKGEPGLLISRVNKKNPFFGYAGSDTHTKSKLLFDVFRKGDVYFNTGDLMFQDQENFVYFWDRLGDTFRWKGENVATTEVADVLGRLDFIQEANVYGVRVPGYEGKAGMTSVILKPNKSLDLEKMYNQVVTSLPAYACPLFLRIQDKMETTGTFKLKKLQLVEEGFDPLKISDPLYFMDNLKKSYVPLTEEIYNQIMSEEVKL", "length": 619 }, "evidence": [ { "id": "MGI:3036230", "url": "https://alliancegenome.org/gene/MGI:3036230#orthology", "database": "AGR" }, { "id": "FB:FBgn0027601", "url": "https://alliancegenome.org/gene/FB:FBgn0027601#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O14975-1", "protein_name": "Long-chain fatty acid transport protein 2", "gene_name": "SLC27A2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLSAIYTVLAGLLFLPLLVNLCCPYFFQDIGYFLKVAAVGRRVRSYGKRRPARTILRAFLEKARQTPHKPFLLFRDETLTYAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEPAYVWLWLGLVKLGCAMACLNYNIRAKSLLHCFQCCGAKVLLVSPELQAAVEEILPSLKKDDVSIYYVSRTSNTDGIDSFLDKVDEVSTEPIPESWRSEVTFSTPALYIYTSGTTGLPKAAMITHQRIWYGTGLTFVSGLKADDVIYITLPFYHSAALLIGIHGCIVAGATLALRTKFSASQFWDDCRKYNVTVIQYIGELLRYLCNSPQKPNDRDHKVRLALGNGLRGDVWRQFVKRFGDICIYEFYAATEGNIGFMNYARKVGAVGRVNYLQKKIITYDLIKYDVEKDEPVRDENGYCVRVPKGEVGLLVCKITQLTPFNGYAGAKAQTEKKKLRDVFKKGDLYFNSGDLLMVDHENFIYFHDRVGDTFRWKGENVATTEVADTVGLVDFVQEVNVYGVHVPDHEGRIGMASIKMKENHEFDGKKLFQHIADYLPSYARPRFLRIQDTIEITGTFKHRKMTLVEEGFNPAVIKDALYFLDDTAKMYVPMTEDIYNAISAKTLKL", "length": 620 }, "evidence": [ { "id": "MGI:1347099", "url": "https://alliancegenome.org/gene/MGI:1347099#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O35488-1", "protein_name": "Long-chain fatty acid transport protein 2", "gene_name": "Slc27a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPVLYTGLAGLLLLPLLLTCCCPYLLQDVRYFLRLANMARRVRSYRQRRPVRTILRAFLEQARKTPHKPFLLFRDETLTYAQVDRRSNQVARALHDQLGLRQGDCVALFMGNEPAYVWIWLGLLKLGCPMACLNYNIRAKSLLHCFQCCGAKVLLASPDLQEAVEEVLPTLKKDAVSVFYVSRTSNTNGVDTILDKVDGVSAEPTPESWRSEVTFTTPAVYIYTSGTTGLPKAATINHHRLWYGTGLAMSSGITAQDVIYTTMPLYHSAALMIGLHGCIVVGATLALRSKFSASQFWDDCRKYNVTVIQYIGELLRYLCNTPQKPNDRDHKVKKALGNGLRGDVWREFIKRFGDIHVYEFYASTEGNIGFVNYPRKIGAVGRANYLQRKVARYELIKYDVEKDEPVRDANGYCIKVPKGEVGLLVCKITQLTPFIGYAGGKTQTEKKKLRDVFKKGDIYFNSGDLLMIDRENFVYFHDRVGDTFRWKGENVATTEVADIVGLVDFVEEVNVYGVPVPGHEGRIGMASLKIKENYEFNGKKLFQHIAEYLPSYARPRFLRIQDTIEITGTFKHRKVTLMEEGFNPTVIKDTLYFMDDAEKTFVPMTENIYNAIIDKTLKL", "length": 620 }, "evidence": [ { "id": "MGI:1347099", "url": "https://alliancegenome.org/gene/MGI:1347099#orthology", "database": "AGR" }, { "id": "FB:FBgn0027601", "url": "https://alliancegenome.org/gene/FB:FBgn0027601#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O88561-1", "protein_name": "Long-chain fatty acid transport protein 3", "gene_name": "Slc27a3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAALLLLLPLLLLLPLLLKLDVWPQLRWLPADLAFTVRALRCKRALRARALAAAAADPESSESGCSLAWRLAYLAREQPTHTFLIHGAQRFSYAEAERESNRIARAFLRARGWTGGRRGSGRGSTEEGARVAPPAGDAAARGTTAPPLAPGATVALLLPAGPDFLWIWFGLAKAGLRTAFVPTALRRGPLLHCLRSCGASALVLATEFLESLEPDLPALRAMGLHLWATGPETNVAGISNLLSEAADQVDEPVPGYLSAPQNIMDTCLYIFTSGTTGLPKAARISHLKVLQCQGFYHLCGVHQEDVIYLALPLYHMSGSLLGIVGCLGIGATVVLKPKFSASQFWDDCQKHRVTVFQYIGELCRYLVNQPPSKAECDHKVRLAVGSGLRPDTWERFLRRFGPLQILETYGMTEGNVATFNYTGRQGAVGRASWLYKHIFPFSLIRYDVMTGEPIRNAQGHCMTTSPGEPGLLVAPVSQQSPFLGYAGAPELAKDKLLKDVFWSGDVFFNTGDLLVCDEQGFLHFHDRTGDTIRWKGENVATTEVAEVLETLDFLQEVNIYGVTVPGHEGRAGMAALALRPPQALNLVQLYSHVSENLPPYARPRFLRLQESLATTETFKQQKVRMANEGFDPSVLSDPLYVLDQDIGAYLPLTPARYSALLSGDLRI", "length": 667 }, "evidence": [ { "id": "MGI:1347358", "url": "https://alliancegenome.org/gene/MGI:1347358#orthology", "database": "AGR" }, { "id": "RGD:1310605", "url": "https://alliancegenome.org/gene/RGD:1310605#orthology", "database": "AGR" }, { "id": "FB:FBgn0027601", "url": "https://alliancegenome.org/gene/FB:FBgn0027601#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P38137-1", "protein_name": "Oxalate--CoA ligase", "gene_name": "PCS60", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTSAATVTASFNDTFSVSDNVAVIVPETDTQVTYRDLSHMVGHFQTMFTNPNSPLYGAVFRQDTVAISMRNGLEFIVAFLGATMDAKIGAPLNPNYKEKEFNFYLNDLKSKAICVPKGTTKLQSSEILKSASTFGCFIVELAFDATRFRVEYDIYSPEDNYKRVIYRSLNNAKFVNTNPVKFPGFARSSDVALILHTSGTTSTPKTVPLLHLNIVRSTLNIANTYKLTPLDRSYVVMPLFHVHGLIGVLLSTFRTQGSVVVPDGFHPKLFWDQFVKYNCNWFSCVPTISMIMLNMPKPNPFPHIRFIRSCSSALAPATFHKLEKEFNAPVLEAYAMTEASHQMTSNNLPPGKRKPGTVGQPQGVTVVILDDNDNVLPPGKVGEVSIRGENVTLGYANNPKANKENFTKRENYFRTGDQGYFDPEGFLVLTGRIKELINRGGEKISPIELDGIMLSHPKIDEAVAFGVPDDMYGQVVQAAIVLKKGEKMTYEELVNFLKKHLASFKIPTKVYFVDKLPKTATGKIQRRVIAETFAKSSRNKSKL", "length": 543 }, "evidence": [ { "id": "FB:FBgn0027601", "url": "https://alliancegenome.org/gene/FB:FBgn0027601#orthology", "database": "AGR" }, { "id": "SGD:S000000426", "url": "https://alliancegenome.org/gene/SGD:S000000426#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P38225-1", "protein_name": "Very long-chain fatty acid transport protein", "gene_name": "FAT1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSPIQVVVFALSRIFLLLFRLIKLIITPIQKSLGYLFGNYFDELDRKYRYKEDWYIIPYFLKSVFCYIIDVRRHRFQNWYLFIKQVQQNGDHLAISYTRPMAEKGEFQLETFTYIETYNIVLRLSHILHFDYNVQAGDYVAIDCTNKPLFVFLWLSLWNIGAIPAFLNYNTKGTPLVHSLKISNITQVFIDPDASNPIRESEEEIKNALPDVKLNYLEEQDLMHELLNSQSPEFLQQDNVRTPLGLTDFKPSMLIYTSGTTGLPKSAIMSWRKSSVGCQVFGHVLHMTNESTVFTAMPLFHSTAALLGACAILSHGGCLALSHKFSASTFWKQVYLTGATHIQYVGEVCRYLLHTPISKYEKMHKVKVAYGNGLRPDIWQDFRKRFNIEVIGEFYAATEAPFATTTFQKGDFGIGACRNYGTIIQWFLSFQQTLVRMDPNDDSVIYRNSKGFCEVAPVGEPGEMLMRIFFPKKPETSFQGYLGNAKETKSKVVRDVFRRGDAWYRCGDLLKADEYGLWYFLDRMGDTFRWKSENVSTTEVEDQLTASNKEQYAQVLVVGIKVPKYEGRAGFAVIKLTDNSLDITAKTKLLNDSLSRLNLPSYAMPLFVKFVDEIKMTDNHKILKKVYREQKLPKGLDGNDTIFWLKNYKRYEVLTAADWEAIDAQTIKL", "length": 669 }, "evidence": [ { "id": "MGI:1347358", "url": "https://alliancegenome.org/gene/MGI:1347358#orthology", "database": "AGR" }, { "id": "MGI:1347099", "url": "https://alliancegenome.org/gene/MGI:1347099#orthology", "database": "AGR" }, { "id": "MGI:3036230", "url": "https://alliancegenome.org/gene/MGI:3036230#orthology", "database": "AGR" }, { "id": "RGD:1310605", "url": "https://alliancegenome.org/gene/RGD:1310605#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P97524-1", "protein_name": "Long-chain fatty acid transport protein 2", "gene_name": "Slc27a2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPVLYTGLAGLLLLPLLLTCCCPYLLQDVRFFLQLANMARQVRSYRQRRPVRTILHVFLEQARKTPHKPFLLFRDETLTYAQVDRRSNQVARALHDHLGLRQGDCVALFMGNEPAYVWLWLGLLKLGCPMACLNYNIRAKSLLHCFQCCGAKVLLASPELHEAVEEVLPTLKKEGVSVFYVSRTSNTNGVDTVLDKVDGVSADPIPESWRSEVTFTTPAVYIYTSGTTGLPKAATINHHRLWYGTSLALRSGIKAHDVIYTTMPLYHSAALMIGLHGCIVVGATFALRSKFSASQFWDDCRKYNATVIQYIGELLRYLCNTPQKPNDRDHKVKIALGNGLRGDVWREFIKRFGDIHIYEFYASTEGNIGFMNYPRKIGAVGRENYLQKKVVRHELIKYDVEKDEPVRDANGYCIKVPKGEVGLLICKITELTPFFGYAGGKTQTEKKKLRDVFKKGDVYFNSGDLLMIDRENFIYFHDRVGDTFRWKGENVATTEVADIVGLVDFVEEVNVYGVPVPGHEGRIGMASIKMKENYEFNGKKLFQHISEYLPSYSRPRFLRIQDTIEITGTFKHRKVTLMEEGFNPSVIKDTLYFMDDTEKTYVPMTEDIYNAIIDKTLKL", "length": 620 }, "evidence": [ { "id": "MGI:1347099", "url": "https://alliancegenome.org/gene/MGI:1347099#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3URE1-1", "protein_name": "Malonate--CoA ligase ACSF3, mitochondrial", "gene_name": "Acsf3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPPHLALPFRRLFWSLASSQLIPRRHRGHSLLPTTPEAHTDGSVPVFIRALAFGDRIALIDKYGHHTYRELYDRSLCLAQEICRLQGCKVGDLQEERVSFLCSNDVSYVVAQWASWMSGGVAVPLYWKHPEAQLEYFIQDSRSSLVVVGQEYLERLSPLAQRLGVPLLPLTPAVYHGATEKPTEQPVEESGWRDRGAMIFYTSGTTGRPKGALSTHRNLAAVVTGLVHSWAWTKNDVILHVLPLHHVHGVVNKLLCPLWVGATCVMLPEFSAQQVWEKFLSSEAPQITVFMAVPTVYSKLLDYYDKHFTQPHVQDFVRAVCKERIRLMVSGSAALPVPLLEKWRSATGHTLLERYGMTEIGMALSNPLTEARVPGSVGTPLPGVEVRIISENPQKGSPYIIHAEGNERGTKVTPGFEEKEGELLVRGPSVFREYWDKPEETKSAFTSDGWFRTGDTAVFKDARYWIRGRTSVDIIKTGGYKVSALEIERHLLAHPSITDVAVIGVPDMTWGQRVTAVVALQEGHSLSHGDLKEWARGVLAPYAVPSELLLVEEIPRNQMGKVNKKELLKQLYPSGQRSQPGQG", "length": 583 }, "evidence": [ { "id": "SGD:S000000426", "url": "https://alliancegenome.org/gene/SGD:S000000426#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q4G176-1", "protein_name": "Malonate--CoA ligase ACSF3, mitochondrial", "gene_name": "ACSF3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLPHVVLTFRRLGCALASCRLAPARHRGSGLLHTAPVARSDRSAPVFTRALAFGDRIALVDQHGRHTYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGGVAVPLYRKHPAAQLEYVICDSQSSVVLASQEYLELLSPVVRKLGVPLLPLTPAIYTGAVEEPAEVPVPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWAWTKDDVILHVLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWEKFLSSETPRINVFMAVPTIYTKLMEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTLLERYGMTEIGMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFEEKEGELLVRGPSVFREYWNKPEETKSAFTLDGWFKTGDTVVFKDGQYWIRGRTSVDIIKTGGYKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHSLSHRELKEWARNVLAPYAVPSELVLVEEIPRNQMGKIDKKALIRHFHPS", "length": 576 }, "evidence": [ { "id": "SGD:S000000426", "url": "https://alliancegenome.org/gene/SGD:S000000426#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5K4L6-1", "protein_name": "Long-chain fatty acid transport protein 3", "gene_name": "SLC27A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAALLLLPLLLLLPLLLLKLHLWPQLRWLPADLAFAVRALCCKRALRARALAAAAADPEGPEGGCSLAWRLAELAQQRAAHTFLIHGSRRFSYSEAERESNRAARAFLRALGWDWGPDGGDSGEGSAGEGERAAPGAGDAAAGSGAEFAGGDGAARGGGAAAPLSPGATVALLLPAGPEFLWLWFGLAKAGLRTAFVPTALRRGPLLHCLRSCGARALVLAPEFLESLEPDLPALRAMGLHLWAAGPGTHPAGISDLLAEVSAEVDGPVPGYLSSPQSITDTCLYIFTSGTTGLPKAARISHLKILQCQGFYQLCGVHQEDVIYLALPLYHMSGSLLGIVGCMGIGATVVLKSKFSAGQFWEDCQQHRVTVFQYIGELCRYLVNQPPSKAERGHKVRLAVGSGLRPDTWERFVRRFGPLQVLETYGLTEGNVATINYTGQRGAVGRASWLYKHIFPFSLIRYDVTTGEPIRDPQGHCMATSPGEPGLLVAPVSQQSPFLGYAGGPELAQGKLLKDVFRPGDVFFNTGDLLVCDDQGFLRFHDRTGDTFRWKGENVATTEVAEVFEALDFLQEVNVYGVTVPGHEGRAGMAALVLRPPHALDLMQLYTHVSENLPPYARPRFLRLQESLATTETFKQQKVRMANEGFDPSTLSDPLYVLDQAVGAYLPLTTARYSALLAGNLRI", "length": 683 }, "evidence": [ { "id": "MGI:1347358", "url": "https://alliancegenome.org/gene/MGI:1347358#orthology", "database": "AGR" }, { "id": "RGD:1310605", "url": "https://alliancegenome.org/gene/RGD:1310605#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q84P21-1", "protein_name": "Peroxisomal OPC-8:0-CoA ligase 1", "gene_name": "4CLL5", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASVNSRSGFCNSNSTFYSKRTPIPLPPNPSLDVTTFISSQAHRGRIAFIDASTGQNLTFTELWRAVESVADCLSEIGIRKGHVVLLLSPNSILFPVVCLSVMSLGAIITTTNPLNTSNEIAKQIKDSNPVLAFTTSQLLPKISAAAKKLPIVLMDEERVDSVGDVRRLVEMMKKEPSGNRVKERVDQDDTATLLYSSGTTGMSKGVISSHRNLIAMVQTIVNRFGSDDGEQRFICTVPMFHIYGLAAFATGLLAYGSTIIVLSKFEMHEMMSAIGKYQATSLPLVPPILVAMVNGADQIKAKYDLSSMHTVLCGGAPLSKEVTEGFAEKYPTVKILQGYGLTESTGIGASTDTVEESRRYGTAGKLSASMEGRIVDPVTGQILGPKQTGELWLKGPSIMKGYFSNEEATSSTLDSEGWLRTGDLCYIDEDGFIFVVDRLKELIKYKGYQVAPAELEALLLTHPEITDAAVIPFPDKEVGQFPMAYVVRKTGSSLSEKTIMEFVAKQVAPYKRIRKVAFVSSIPKNPSGKILRKDLIKIATSNSKL", "length": 546 }, "evidence": [ { "id": "Q9VXZ8", "url": "https://omabrowser.org/oma/group/Q9VXZ8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VCC6-1", "protein_name": "Luciferin 4-monooxygenase", "gene_name": "Dmel\\CG6178", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTSKLLPGNIVYGGPVTERQAQDSRSLGQYILDKYKSFGDRTVLVDAVNGVEYSASFMHKSIVRLAYILQKLGVKQNDVVGLSSENSVNFALAMFAGLAVGATVAPLNVTYSDREVDHAINLSKPKIIFASKITIDRVAKVASKNKFVKGIIALSGTSKKFKNIYDLKELMEDEKFKTQPDFTSPAANKDEDVSLIVCSSGTTGLPKGVQLTQMNLLATLDSQIQPTVIPMEEVTLLTVIPWFHAFGCLTLITTACVGARLVYLPKFEEKLFLSAIEKYRVMMAFMVPPLMVFLAKHPIVDKYDLSSLMVLLCGAAPLSRETEDQIKERIGVPFIRQGYGLSESTLSVLVQNDEFCKPGSVGVLKVGIYAKVIDPDTGKLLGANERGELCFKGDGIMKGYIGDTKSTQTAIKDGWLHTGDIGYYDDDFEFFIVDRIKELIKYKGYQVPPAEIEALLLTNDKIKDAAVIGKPDEEAGELPLAFVVKQANVQLTENEVIQFVNDNASPAKRLRGGVIFVDEIPKNPSGKILRRILREMLKKQKSKL", "length": 544 }, "evidence": [ { "id": "SGD:S000000426", "url": "https://alliancegenome.org/gene/SGD:S000000426#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VGC5-1", "protein_name": "Long-chain-fatty-acid--CoA ligase", "gene_name": "Acsx5", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSKLPCSYDAENKIWKGIPQNNPFKPETSLGRIIFKNMRNWPKNVCQISDSEGVEVTFGQALTWAIRIAQQLKSRGLDHKDIIGISARNTTYIMPTAVACFFHGTPFQSANPILEESTLKHLYNISKPKIIFTDADHYDKLYSATSAFKPEIILTTGTKDGVLSIQDLLAPTKTEFFYQPTPLKEGPSQTVAILTSSGTTGMPKAVCISNDILTQETVFVNGYDTIFISASLDWITGLWATIFSTVNGCTRIISSKPFAADYFVYLVSKYSITYALIPPEHCCSLLDCPTATPEKLGSLTKLNFGGGRMTQATVERVKKLAPNGVLNSSYGMTEVGFIVFNHGHLKLTAAGNPLPGIQVKIVDDDGNQLGVNQTGEIIVHNGFSWNGYFADPEATKAMQDEEGWFHTGDMGYFDEDDYLYMTDRKKEVLKWKGLQMWPAEVEAVIDELPEVKRVCVIGVYDETQGDVPGALVVREDNATLTAQQVIDHVAKRLPDIQKQLRAGVQFADEIPQNHNGKVVRRYARDLFVALSKKN", "length": 534 }, "evidence": [ { "id": "RGD:1310605", "url": "https://alliancegenome.org/gene/RGD:1310605#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y2P4-1", "protein_name": "Long-chain fatty acid transport protein 6", "gene_name": "SLC27A6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLLSWLTVLGAGMVVLHFLQKLLFPYFWDDFWFVLKVVLIIIRLKKYEKRGELVTVLDKFLSHAKRQPRKPFIIYEGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGADLLGTVEEILPSLSENISVWGMKDSVPQGVISLKEKLSTSPDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQVLRGSAVLWAFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWSDCKKYDVTVFQYIGELCRYLCKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAATESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFRWKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEKVYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLKKSYVLLTRELYDQIMLGEIKL", "length": 619 }, "evidence": [ { "id": "MGI:3036230", "url": "https://alliancegenome.org/gene/MGI:3036230#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "long-chain fatty acid metabolic process", "id": "GO:0001676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001676", "evidence": [ { "database": "UniProtKB", "id": "Q9VXZ8", "url": "https://www.uniprot.org/uniprotkb/Q9VXZ8" } ], "pmid": "" }, { "name": "fatty-acyl-CoA biosynthetic process", "id": "GO:0046949", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046949", "evidence": [ { "database": "UniProtKB", "id": "Q9VXZ8", "url": "https://www.uniprot.org/uniprotkb/Q9VXZ8" } ], "pmid": "" }, { "name": "triglyceride catabolic process", "id": "GO:0019433", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019433", "evidence": [ { "database": "UniProtKB", "id": "Q9VXZ8", "url": "https://www.uniprot.org/uniprotkb/Q9VXZ8" } ], "pmid": "" }, { "name": "bioluminescence", "id": "GO:0008218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008218", "evidence": [ { "database": "UniProtKB", "id": "Q9VXZ8", "url": "https://www.uniprot.org/uniprotkb/Q9VXZ8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VXZ8", "url": "https://www.uniprot.org/uniprotkb/Q9VXZ8" } ], "pmid": "" }, { "name": "long-chain fatty acid-CoA ligase activity", "id": "GO:0004467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004467", "evidence": [ { "database": "UniProtKB", "id": "Q9VXZ8", "url": "https://www.uniprot.org/uniprotkb/Q9VXZ8" } ], "pmid": "" }, { "name": "monooxygenase activity", "id": "GO:0004497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004497", "evidence": [ { "database": "UniProtKB", "id": "Q9VXZ8", "url": "https://www.uniprot.org/uniprotkb/Q9VXZ8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9VXZ8", "url": "https://www.uniprot.org/uniprotkb/Q9VXZ8" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "Q9VXZ8", "url": "https://www.uniprot.org/uniprotkb/Q9VXZ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 267, "end_pos": 269, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10732", "name": "", "equation": "firefly D-luciferin + ATP + O2 = firefly oxyluciferin + hnu + AMP + CO2 + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VCC6-1", "Q9VXZ8-1" ], "evidence": [ { "id": "10732", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10732" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "Q9VCC6", "gene_name": "Dmel\\CG6178", "activity": [ { "ec_number": "1.13.12.7", "activity": "firefly D-luciferin + ATP + O2 = firefly oxyluciferin + 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"https://www.rhea-db.org/rhea/?query=ec:1.13.12.7" } ] } ], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 267, "end_pos": 269 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"type": "recommended", "evidence": [ { "id": "Q9VY18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VY18/entry#names_and_taxonomy" } ] }, { "name": "Ag5r-PB", "type": "synonym", "evidence": [ { "id": "NP_001245671", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245671" } ] }, { "name": "CG9538-PB", "type": "synonym", "evidence": [ { "id": "NP_001245671", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245671" } ] }, { "name": "antigen 5-related, isoform B", "type": "synonym", "evidence": [ { "id": "NP_001245671", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245671" } ] }, { "name": "antigen 5-related", "type": "synonym", "evidence": [ { "id": "NP_001245671", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245671" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VY18", "url": "https://www.uniprot.org/uniprotkb/Q9VY18" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Ag5r", "url": "https://www.uniprot.org/uniprotkb/Q9VY18", "locus": { "chromosome": "X", "start_pos": 14784664, "end_pos": 14786551, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0015010", "url": "https://www.ensemblgenomes.org/id/FBgn0015010" } ] } } ], "crossref": [ { "id": "FB:FBgn0015010", "url": "https://alliancegenome.org/gene/FB:FBgn0015010", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0015010", "url": "https://bgee.org/?page=gene&gene_id=FBgn0015010", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05380", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05380", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0015010", "url": "https://flybase.org/reports/FBgn0015010", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "44631", "url": "https://www.ncbi.nlm.nih.gov/gene/44631", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001283", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001283", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034763", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034763", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035940", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035940", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG9538", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG9538", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HNEYRNF", "url": "https://omabrowser.org/oma/group/HNEYRNF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VY18", "url": "https://www.orthodb.org/?gene=Q9VY18", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10334", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10334", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00188", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00188", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001245671", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245671", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VY18", "url": "https://www.uniprot.org/uniprotkb/Q9VY18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VY18-1", "url": "https://www.uniprot.org/uniprotkb/Q9VY18-1", "database": 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GN=Ag5r PE=3 SV=1 CANONICAL=Q9VY18-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VY18", "url": "https://www.uniprot.org/uniprotkb/Q9VY18" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VY18", "url": "https://www.uniprot.org/uniprotkb/Q9VY18" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VY18", "url": "https://www.uniprot.org/uniprotkb/Q9VY18" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VY18", "url": "https://www.uniprot.org/uniprotkb/Q9VY18" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VY18", "url": 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Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VY18", "url": "https://www.uniprot.org/uniprotkb/Q9VY18" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VY18", "url": "https://www.uniprot.org/uniprotkb/Q9VY18" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VY18", "url": "https://www.uniprot.org/uniprotkb/Q9VY18" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VY18", "url": "https://www.uniprot.org/uniprotkb/Q9VY18" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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254, "header": "tr|Q9VY19-1|Q9VY19_DROME Isoform 1 of Venom allergen-1 OS=Drosophila melanogaster OX=7227 GN=Ag5r2 PE=1 SV=1 CANONICAL=Q9VY19-1" }, "isoforms": [ { "isoform_ac": "Q9VY19-1", "url": "https://www.uniprot.org/uniprotkb/Q9VY19/entry#Q9VY19-1", "sequence": { "sequence": "MKLALLAILIVSLALAQATDYCSSDICNGGSHIACGHSNWWDSSCPGDAELIDINDDYKWVFVHSHNDKRNYIAGGYDSNHNAACRMATMEWDDELAYLASLNVRQCNMVHDSCHNTDAFKYSGQNLAWQAYSGDLPDMGYILDNSVQMWFDEVHNSNAGIIAGGYPSGYNGPAIGHFTVMMSERNTRLGCAAARYNRDGWNQVLVACNYATTNMIGRQIYSSCDWGAQGCGSGTNGEFGNLCSTSEWYDVNSW", "length": 254, "header": "tr|Q9VY19-1|Q9VY19_DROME Isoform 1 of Venom allergen-1 OS=Drosophila melanogaster OX=7227 GN=Ag5r2 PE=1 SV=1 CANONICAL=Q9VY19-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VY19", "url": "https://www.uniprot.org/uniprotkb/Q9VY19" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VY19", "url": "https://www.uniprot.org/uniprotkb/Q9VY19" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VY19", "url": "https://www.uniprot.org/uniprotkb/Q9VY19" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VY19", "url": "https://www.uniprot.org/uniprotkb/Q9VY19" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VY19", "url": "https://www.uniprot.org/uniprotkb/Q9VY19" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VY19", "url": "https://www.uniprot.org/uniprotkb/Q9VY19" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VY19", "url": "https://www.uniprot.org/uniprotkb/Q9VY19" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VY19", "url": "https://www.uniprot.org/uniprotkb/Q9VY19" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VY19", "url": "https://www.uniprot.org/uniprotkb/Q9VY19" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VY19", "url": "https://www.uniprot.org/uniprotkb/Q9VY19" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VY19", "url": "https://www.uniprot.org/uniprotkb/Q9VY19" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG9540", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG9540", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q9VY19", "url": "https://www.uniprot.org/uniprotkb/Q9VY19" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9VY19", "url": "https://www.uniprot.org/uniprotkb/Q9VY19" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VY19" }, { "id": "SM00198", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00198" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SCP", "eco_id": "ECO_0000259", "start_pos": 57, "end_pos": 217, "start_aa": "Asp", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VY27-1", "uniprot_ac": "Q9VY27", "uniprot_id": "Q9VY27_DROME", "mass": { "chemical_mass": 17211.0, "monoisotopic_mass": 17211.0 }, "refseq": { "ac": "NP_572965", "name": "nmdyn-D6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572965" }, "gene_names": [ { "name": "nmdyn-D6", "type": "recommended", "evidence": [ { "id": "Q9VY27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VY27" } ] }, { "name": "CG5310", "type": "synonym", "evidence": [ { "id": "NP_572965", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572965" }, { "id": "Q9VY27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VY27" } ] }, { "name": "Dmel\\CG5310", "type": "synonym", "evidence": [ { "id": "NP_572965", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572965" }, { "id": "Q9VY27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VY27" } ] }, { "name": "Dmel_CG5310", "type": "synonym", "evidence": [ { "id": "Q9VY27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VY27" } ] }, { "name": "nmdyn-D6", "type": "synonym", "evidence": [ { "id": "NP_572965", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572965" } ] } ], "protein_names": [ { "name": "Nucleoside diphosphate kinase", "type": "recommended", "evidence": [ { "id": "Q9VY27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VY27/entry#names_and_taxonomy" } ] }, { "name": "2.7.4.6", "type": "synonym", "evidence": [ { "id": "Q9VY27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VY27/entry#names_and_taxonomy" } ] }, { "name": "CG5310-PA", "type": "synonym", "evidence": [ { "id": "NP_572965", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572965" } ] }, { "name": "nmdyn-D6-PA", "type": "synonym", "evidence": [ { "id": "NP_572965", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572965" } ] }, { "name": "nmdyn-D6", "type": "synonym", "evidence": [ { "id": "NP_572965", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572965" } ] } ], "function": [ { "annotation": "Catalytic subunit of a complex with RCC1L, which catalyzes the transfer of a gamma-phosphoryl group from a nucleoside triphosphate, mainly ATP, to a nucleoside diphosphate via a ping-pong mechanism involving the formation of a phosphohistidine intermediate. Participates in the regulation of mitochondrial nucleotide levels, mitoribosome biogenesis, and mitochondrial RNA abundances. Supplies pyrimidine ribonucleoside triphosphates (rNTPs) for mitochondrial transcription and is required for the maintenance of mitochondrial DNA (mtDNA) when the import of pyrimidine deoxyribonucleoside triphosphates (dNTPs) is limited from the cytosol is limited. As a monomer, lacks nucleoside diphosphate kinase (NDPK) activity.", "evidence": [ { "database": "UniProtKB", "id": "Q9VY27", "url": "https://www.uniprot.org/uniprotkb/Q9VY27#function" }, { "database": "UniProtKB", "id": "ARBA00094157", "url": "https://www.uniprot.org/uniprotkb/ARBA00094157#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VY27", "url": "https://www.uniprot.org/uniprotkb/Q9VY27" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "nmdyn-D6", "url": "https://www.uniprot.org/uniprotkb/Q9VY27", "locus": { "chromosome": "X", "start_pos": 14584616, "end_pos": 14583677, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0030573", "url": "https://www.ensemblgenomes.org/id/FBgn0030573" } ] } } ], "crossref": [ { "id": "FB:FBgn0030573", "url": "https://alliancegenome.org/gene/FB:FBgn0030573", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0030573", "url": "https://bgee.org/?page=gene&gene_id=FBgn0030573", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04414", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04414", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0030573", "url": "https://flybase.org/reports/FBgn0030573", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "32396", "url": "https://www.ncbi.nlm.nih.gov/gene/32396", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001564", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001564", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023005", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023005", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036850", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036850", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037994", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037994", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG5310", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG5310", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YHRLTSF", "url": "https://omabrowser.org/oma/group/YHRLTSF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VY27", "url": "https://www.orthodb.org/?gene=Q9VY27", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46161", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46161", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46161:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46161:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00334", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00334", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_572965", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572965", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "18113", "url": "https://www.rhea-db.org/rhea/18113", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "25098", "url": "https://www.rhea-db.org/rhea/25098", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "25237", "url": "https://www.rhea-db.org/rhea/25237", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "44640", "url": "https://www.rhea-db.org/rhea/44640", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q9VY27", "url": "https://www.uniprot.org/uniprotkb/Q9VY27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VY27-1", "url": "https://www.uniprot.org/uniprotkb/Q9VY27-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEITLALIKPHVLRNTYAMQQIRALISQNFTILDQKEVCITKELSERFYAEHKGKFFYHRLTSFMNSGPSYALILQSETCIQKWRSLLGPTKVFRAVYSDPNCIRALYGISDTRNACHGSDSEASALREISILFPEFDAAVGSRQAKREEA", "length": 151, "header": "tr|Q9VY27-1|Q9VY27_DROME Isoform 1 of Nucleoside diphosphate kinase OS=Drosophila melanogaster OX=7227 GN=nmdyn-D6 PE=3 SV=2 CANONICAL=Q9VY27-1" }, "isoforms": [ { "isoform_ac": "Q9VY27-1", "url": "https://www.uniprot.org/uniprotkb/Q9VY27/entry#Q9VY27-1", "sequence": { "sequence": "MEITLALIKPHVLRNTYAMQQIRALISQNFTILDQKEVCITKELSERFYAEHKGKFFYHRLTSFMNSGPSYALILQSETCIQKWRSLLGPTKVFRAVYSDPNCIRALYGISDTRNACHGSDSEASALREISILFPEFDAAVGSRQAKREEA", "length": 151, "header": "tr|Q9VY27-1|Q9VY27_DROME Isoform 1 of Nucleoside diphosphate kinase OS=Drosophila melanogaster OX=7227 GN=nmdyn-D6 PE=3 SV=2 CANONICAL=Q9VY27-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VY27", "url": "https://www.uniprot.org/uniprotkb/Q9VY27" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VY27", "url": "https://www.uniprot.org/uniprotkb/Q9VY27" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VY27", "url": "https://www.uniprot.org/uniprotkb/Q9VY27" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VY27", "url": "https://www.uniprot.org/uniprotkb/Q9VY27" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VY27", "url": "https://www.uniprot.org/uniprotkb/Q9VY27" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VY27", "url": "https://www.uniprot.org/uniprotkb/Q9VY27" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VY27", "url": "https://www.uniprot.org/uniprotkb/Q9VY27" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VY27", "url": "https://www.uniprot.org/uniprotkb/Q9VY27" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VY27", "url": "https://www.uniprot.org/uniprotkb/Q9VY27" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VY27", "url": "https://www.uniprot.org/uniprotkb/Q9VY27" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VY27", "url": "https://www.uniprot.org/uniprotkb/Q9VY27" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG5310", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG5310", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "O75414-1", "protein_name": "Nucleoside diphosphate kinase 6, mitochondrial", "gene_name": "NME6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASILRSPQALQLTLALIKPDAVAHPLILEAVHQQILSNKFLIVRMRELLWRKEDCQRFYREHEGRFFYQRLVEFMASGPIRAYILAHKDAIQLWRTLMGPTRVFRARHVAPDSIRGSFGLTDTRNTTHGSDSVVSASREIAAFFPDFSEQRWYEEEEPQLRCGPVCYSPEGGVHYVAGTGGLGPA", "length": 186 }, "evidence": [ { "id": "HGNC:20567", "url": "https://alliancegenome.org/gene/HGNC:20567#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-000710-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-000710-3#orthology", "database": "AGR" }, { "id": "RGD:61896", "url": "https://alliancegenome.org/gene/RGD:61896#orthology", "database": "AGR" }, { "id": "MGI:1861676", "url": 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Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VY55", "url": "https://www.uniprot.org/uniprotkb/Q9VY55" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", 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of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VY55", "url": "https://www.uniprot.org/uniprotkb/Q9VY55" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VY55", "url": "https://www.uniprot.org/uniprotkb/Q9VY55" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VY55", "url": "https://www.uniprot.org/uniprotkb/Q9VY55" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VY55", "url": "https://www.uniprot.org/uniprotkb/Q9VY55" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VY55", "url": "https://www.uniprot.org/uniprotkb/Q9VY55" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VY55", "url": "https://www.uniprot.org/uniprotkb/Q9VY55" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VY55", "url": "https://www.uniprot.org/uniprotkb/Q9VY55" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VY55", "url": "https://www.uniprot.org/uniprotkb/Q9VY55" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VY59" } ] }, { "name": "Dmel\\CG12481", "type": "synonym", "evidence": [ { "id": "NP_001033843", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001033843" } ] }, { "name": "Dmel_CG12481", "type": "synonym", "evidence": [ { "id": "Q9VY59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VY59" } ] } ], "protein_names": [ { "name": "CG12481-PB", "type": "synonym", "evidence": [ { "id": "NP_001033843", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001033843" } ] }, { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "Q9VY59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VY59/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_001033843", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001033843" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VY59", "url": "https://www.uniprot.org/uniprotkb/Q9VY59" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG12481", "url": "https://www.uniprot.org/uniprotkb/Q9VY59", "locus": { "chromosome": "X", "start_pos": 14187841, "end_pos": 14187253, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0030542", "url": "https://www.ensemblgenomes.org/id/FBgn0030542" } ] } } ], "crossref": [ { "id": "FB:FBgn0030542", "url": "https://alliancegenome.org/gene/FB:FBgn0030542", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0030542", "url": "https://bgee.org/?page=gene&gene_id=FBgn0030542", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0030542", "url": "https://flybase.org/reports/FBgn0030542", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "32364", "url": "https://www.ncbi.nlm.nih.gov/gene/32364", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dme:Dmel_CG12481", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG12481", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MIYQRIT", "url": "https://omabrowser.org/oma/group/MIYQRIT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VY59", "url": "https://www.orthodb.org/?gene=Q9VY59", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "NP_001033843", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001033843", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VY59", "url": "https://www.uniprot.org/uniprotkb/Q9VY59", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VY59-1", "url": "https://www.uniprot.org/uniprotkb/Q9VY59-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWTKSSVVIVAMALLASTGAQPVSQTEMEPMLINVTTSRPKLVIEEMEPMRYHFVTEHRPTSLGQNYYIKPGQPVGSITLDSDTLQVRYDQDDGKPVASKHNILFVAYAKDLAQKSRQRK", "length": 120, "header": "tr|Q9VY59-1|Q9VY59_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG12481 PE=4 SV=2 CANONICAL=Q9VY59-1" }, "isoforms": [ { "isoform_ac": "Q9VY59-1", "url": "https://www.uniprot.org/uniprotkb/Q9VY59/entry#Q9VY59-1", "sequence": { "sequence": "MWTKSSVVIVAMALLASTGAQPVSQTEMEPMLINVTTSRPKLVIEEMEPMRYHFVTEHRPTSLGQNYYIKPGQPVGSITLDSDTLQVRYDQDDGKPVASKHNILFVAYAKDLAQKSRQRK", "length": 120, "header": "tr|Q9VY59-1|Q9VY59_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG12481 PE=4 SV=2 CANONICAL=Q9VY59-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VY59", "url": "https://www.uniprot.org/uniprotkb/Q9VY59" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VY59", "url": "https://www.uniprot.org/uniprotkb/Q9VY59" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VY59", "url": "https://www.uniprot.org/uniprotkb/Q9VY59" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VY59", "url": "https://www.uniprot.org/uniprotkb/Q9VY59" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VY59", "url": "https://www.uniprot.org/uniprotkb/Q9VY59" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VY59", "url": "https://www.uniprot.org/uniprotkb/Q9VY59" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VY59", "url": "https://www.uniprot.org/uniprotkb/Q9VY59" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VY59", "url": "https://www.uniprot.org/uniprotkb/Q9VY59" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VY59", "url": "https://www.uniprot.org/uniprotkb/Q9VY59" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VY79", "url": "https://www.uniprot.org/uniprotkb/Q9VY79" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VY79", "url": "https://www.uniprot.org/uniprotkb/Q9VY79" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VY79", "url": "https://www.uniprot.org/uniprotkb/Q9VY79" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VY79", "url": "https://www.uniprot.org/uniprotkb/Q9VY79" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VY79", "url": "https://www.uniprot.org/uniprotkb/Q9VY79" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VY79", "url": "https://www.uniprot.org/uniprotkb/Q9VY79" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VY79", "url": "https://www.uniprot.org/uniprotkb/Q9VY79" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VY79", "url": "https://www.uniprot.org/uniprotkb/Q9VY79" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VY79", "url": "https://www.uniprot.org/uniprotkb/Q9VY79" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VY79", "url": "https://www.uniprot.org/uniprotkb/Q9VY79" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VY79", "url": "https://www.uniprot.org/uniprotkb/Q9VY79" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], 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MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, 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HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VY91", "url": "https://www.uniprot.org/uniprotkb/Q9VY91" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VY91", "url": "https://www.uniprot.org/uniprotkb/Q9VY91" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VY91", "url": "https://www.uniprot.org/uniprotkb/Q9VY91" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VY91", "url": "https://www.uniprot.org/uniprotkb/Q9VY91" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VY91", "url": "https://www.uniprot.org/uniprotkb/Q9VY91" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VY91", "url": "https://www.uniprot.org/uniprotkb/Q9VY91" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VY91", "url": "https://www.uniprot.org/uniprotkb/Q9VY91" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VY91", "url": "https://www.uniprot.org/uniprotkb/Q9VY91" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VY91", "url": "https://www.uniprot.org/uniprotkb/Q9VY91" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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[7227]" } ], "gene": [ { "name": "Dmel\\CG11151", "url": "https://www.uniprot.org/uniprotkb/Q9VY92", "locus": { "chromosome": "X", "start_pos": 13741952, "end_pos": 13739744, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0030519", "url": "https://www.ensemblgenomes.org/id/FBgn0030519" } ] } } ], "crossref": [ { "id": "FB:FBgn0030519", "url": "https://alliancegenome.org/gene/FB:FBgn0030519", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0030519", "url": "https://bgee.org/?page=gene&gene_id=FBgn0030519", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0030519", "url": "https://flybase.org/reports/FBgn0030519", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "32335", "url": "https://www.ncbi.nlm.nih.gov/gene/32335", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003033", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003033", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG11151", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG11151", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WDIMNGG", "url": "https://omabrowser.org/oma/group/WDIMNGG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VY92", "url": "https://www.orthodb.org/?gene=Q9VY92", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10094", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10094", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10094:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10094:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02036", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02036", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001259531", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259531", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VY92", "url": "https://www.uniprot.org/uniprotkb/Q9VY92", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VY92-1", "url": "https://www.uniprot.org/uniprotkb/Q9VY92-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLQSDAVFQKIIDGLKENEAKAKAVNGVFLYKITKDGKVAKEWTLDCKNAKAYEGPAQGIKVDTTLTVADEDMVDIALGKLNPQAAFMKGKLKIAGNIMLTQKLAPLLKTDAKL", "length": 115, "header": "tr|Q9VY92-1|Q9VY92_DROME Isoform 1 of SCP2 domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG11151 PE=1 SV=1 CANONICAL=Q9VY92-1" }, "isoforms": [ { "isoform_ac": "Q9VY92-1", "url": "https://www.uniprot.org/uniprotkb/Q9VY92/entry#Q9VY92-1", "sequence": { "sequence": "MSLQSDAVFQKIIDGLKENEAKAKAVNGVFLYKITKDGKVAKEWTLDCKNAKAYEGPAQGIKVDTTLTVADEDMVDIALGKLNPQAAFMKGKLKIAGNIMLTQKLAPLLKTDAKL", "length": 115, "header": "tr|Q9VY92-1|Q9VY92_DROME Isoform 1 of SCP2 domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG11151 PE=1 SV=1 CANONICAL=Q9VY92-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VY92", "url": "https://www.uniprot.org/uniprotkb/Q9VY92" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VY92", "url": "https://www.uniprot.org/uniprotkb/Q9VY92" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VY92", "url": "https://www.uniprot.org/uniprotkb/Q9VY92" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VY92", "url": "https://www.uniprot.org/uniprotkb/Q9VY92" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VY92", "url": "https://www.uniprot.org/uniprotkb/Q9VY92" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VY92", "url": "https://www.uniprot.org/uniprotkb/Q9VY92" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VY92", "url": "https://www.uniprot.org/uniprotkb/Q9VY92" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VY92", "url": "https://www.uniprot.org/uniprotkb/Q9VY92" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VY92", "url": "https://www.uniprot.org/uniprotkb/Q9VY92" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VY92", "url": "https://www.uniprot.org/uniprotkb/Q9VY92" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VY92", "url": "https://www.uniprot.org/uniprotkb/Q9VY92" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], 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"url": "https://www.orthodb.org/?gene=Q9VYA4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13383", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13383", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13383:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13383:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09468", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09468", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17745", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17745", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001285220", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285220", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VYA4", "url": "https://www.uniprot.org/uniprotkb/Q9VYA4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VYA4-1", "url": "https://www.uniprot.org/uniprotkb/Q9VYA4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGKKETRARKPKADPDAEGSAKMCKASALKKVFFMSEELLPKDADDGHLRLEMFFHPGHGKEALFITHPDGRMMELVAFTEPRRSWFVDSEVCSNGRIYMTAPVDPTFLALHHLRKHCAQRAISLDNIAVEEASTSRLLNEILDPGNLKCVADVKSSGEQKFYKYNQERTLAWLALKTRQVAKILKEKQVHCGHSAQSQNFVRSEKLVAENVSNEMDYTRMACDYVGRYLDADLHGLLTSYLHIPSEIQAIVEEKAASQKRKSVAGKNEGSDSKKIKLNESDAAAKLKSSGLVDSDGDPNATITSPTAAPLKERSLTAKEKALAKGAKGTKSIASFFKAK", "length": 340, "header": "tr|Q9VYA4-1|Q9VYA4_DROME Isoform 1 of Ribonuclease H2 subunit B OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG11164 PE=1 SV=1 CANONICAL=Q9VYA4-1" }, "isoforms": [ { "isoform_ac": "Q9VYA4-1", "url": "https://www.uniprot.org/uniprotkb/Q9VYA4/entry#Q9VYA4-1", "sequence": { "sequence": "MGKKETRARKPKADPDAEGSAKMCKASALKKVFFMSEELLPKDADDGHLRLEMFFHPGHGKEALFITHPDGRMMELVAFTEPRRSWFVDSEVCSNGRIYMTAPVDPTFLALHHLRKHCAQRAISLDNIAVEEASTSRLLNEILDPGNLKCVADVKSSGEQKFYKYNQERTLAWLALKTRQVAKILKEKQVHCGHSAQSQNFVRSEKLVAENVSNEMDYTRMACDYVGRYLDADLHGLLTSYLHIPSEIQAIVEEKAASQKRKSVAGKNEGSDSKKIKLNESDAAAKLKSSGLVDSDGDPNATITSPTAAPLKERSLTAKEKALAKGAKGTKSIASFFKAK", "length": 340, "header": "tr|Q9VYA4-1|Q9VYA4_DROME Isoform 1 of Ribonuclease H2 subunit B OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG11164 PE=1 SV=1 CANONICAL=Q9VYA4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VYA4", "url": "https://www.uniprot.org/uniprotkb/Q9VYA4" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VYA4", "url": "https://www.uniprot.org/uniprotkb/Q9VYA4" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VYA4", "url": "https://www.uniprot.org/uniprotkb/Q9VYA4" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VYA4", "url": "https://www.uniprot.org/uniprotkb/Q9VYA4" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VYA4", "url": "https://www.uniprot.org/uniprotkb/Q9VYA4" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VYA4", "url": "https://www.uniprot.org/uniprotkb/Q9VYA4" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VYA4", "url": "https://www.uniprot.org/uniprotkb/Q9VYA4" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VYA4", "url": "https://www.uniprot.org/uniprotkb/Q9VYA4" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VYA4", "url": "https://www.uniprot.org/uniprotkb/Q9VYA4" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VYA4", "url": "https://www.uniprot.org/uniprotkb/Q9VYA4" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VYA4", "url": "https://www.uniprot.org/uniprotkb/Q9VYA4" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG11164", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG11164", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q55D33-1", "protein_name": "Ribonuclease H2 subunit B", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTSKIDEIDIDNGEEVFEEIEDFEDEDSDDGVSKSKSDSNRKRKVSTPALKPHPPIPKLPYNDRVFIIQQPKNDTNIIDYEILTLPSPKHKSVKCRYILDKENDRILEINKFNSKPSSWFIDNGVRHDGSMYLSSDIDPLFLLIPFLEKYKSLHKNEYLEISSIINDSYYCNLSKIPFKHSQLSLICDSKEIAGSKLYRLEDEKLLIWLRCKVKNISNYLKETNTDIFKTSNYVKKDLSWETLYTMSIGFVSEYLSESNCKMLNQSFNLLSATAQQTIKSESEYLVYTERIIDEPEPPKSKRGASKKAPAKKSPVKGGGISNFLSLKNDTPTPITVPSLKPSKKSEPIIPTTTTIAAETKGKITDFFTKIT", "length": 371 }, "evidence": [ { "id": "Q9VYA4", "url": "https://omabrowser.org/oma/group/Q9VYA4/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5TBB1-1", "protein_name": "Ribonuclease H2 subunit B", "gene_name": "RNASEH2B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAGVDCGDGVGARQHVFLVSEYLKDASKKMKNGLMFVKLVNPCSGEGAIYLFNMCLQQLFEVKVFKEKHHSWFINQSVQSGGLLHFATPVDPLFLLLHYLIKADKEGKFQPLDQVVVDNVFPNCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAALKTNNVNVSSRVQSTAFFSGDQASTDKEEDYIRYAHGLISDYIPKELSDDLSKYLKLPEPSASLPNPPSKKIKLSDEPVEAKEDYTKFNTKDLKTEKKNSKMTAAQKALAKVDKSGMKSIDTFFGVKNKKKIGKV", "length": 312 }, "evidence": [ { "id": "RGD:1359710", "url": "https://alliancegenome.org/gene/RGD:1359710#orthology", "database": "AGR" }, { "id": "HGNC:25671", "url": "https://alliancegenome.org/gene/HGNC:25671#orthology", "database": "AGR" }, { "id": "MGI:1914403", "url": "https://alliancegenome.org/gene/MGI:1914403#orthology", "database": "AGR" }, { "id": "FB:FBgn0030507", "url": "https://alliancegenome.org/gene/FB:FBgn0030507#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5XI96-1", "protein_name": "Ribonuclease H2 subunit B", "gene_name": "Rnaseh2b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGGRDRGDLAARQLVFLLPEYLKDASRKSKSGLLFVKLVNPHSGEGATYLIDACLQKLFEIKVFKEKHHSWFINQSVQSGGLLHFATPMDPLFLLLHYLIKAGKEGKYQPLDQVVVDDKFPDCTLLLRFPELEKSLRHVTEEKEVNSKKYYKYSTEKTLKWLEKKVNQTVAALKANHVNVGARVQSSAYFSGVQVSRDKEEDYVRYAHGLISDYIPKELSDDLSKLLKLPEPPASLPNPPAKKLKLADEPVEAKEDYTKFNTKDLKNGKKNSKMTAAQKALAKVDKSGMKSIDAFFGAKNKKTGKI", "length": 307 }, "evidence": [ { "id": "RGD:1359710", "url": "https://alliancegenome.org/gene/RGD:1359710#orthology", "database": "AGR" }, { "id": "HGNC:25671", "url": "https://alliancegenome.org/gene/HGNC:25671#orthology", "database": "AGR" }, { "id": "MGI:1914403", "url": "https://alliancegenome.org/gene/MGI:1914403#orthology", "database": "AGR" }, { "id": "FB:FBgn0030507", "url": "https://alliancegenome.org/gene/FB:FBgn0030507#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80ZV0-1", "protein_name": "Ribonuclease H2 subunit B", "gene_name": "Rnaseh2b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGGRDRGDLAARQLVFLLPEHLKDASKKKKKSSLLFVKLANPHSGEGATYLIDMCLQQLFEIKVFKEKHHSWFINQSVQSGGLLHFATPMDPLFLLLHYLLKAGKEGKYQPLDQVVVDDTFPDCTLLLRFPELEKSLRHVTEEKEVNSKKYYKYSSEKTLKWLEKKVNQTVVALKANNVNVGARVQSSAYFSGGQVSRDKEEDYVRYAHGLISDYIPKELSDDLSKFLKLPEPPASLTNPPSKKLKLSDEPVEAKEDYTKFNTKDLKTGKKNSKMTAAQKALAKVDKSGMKSIDAFFGAKNKKTGKI", "length": 308 }, "evidence": [ { "id": "RGD:1359710", "url": "https://alliancegenome.org/gene/RGD:1359710#orthology", "database": "AGR" }, { "id": "HGNC:25671", "url": "https://alliancegenome.org/gene/HGNC:25671#orthology", "database": "AGR" }, { "id": "MGI:1914403", "url": "https://alliancegenome.org/gene/MGI:1914403#orthology", "database": "AGR" }, { "id": "FB:FBgn0030507", "url": "https://alliancegenome.org/gene/FB:FBgn0030507#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q9VYA4", "url": "https://www.uniprot.org/uniprotkb/Q9VYA4" } ], "pmid": "" }, { "name": "ribonuclease H2 complex", "id": "GO:0032299", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032299", "evidence": [ { "database": "UniProtKB", "id": "Q9VYA4", "url": "https://www.uniprot.org/uniprotkb/Q9VYA4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "RNA catabolic process", "id": "GO:0006401", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006401", "evidence": [ { "database": "UniProtKB", "id": "Q9VYA4", "url": "https://www.uniprot.org/uniprotkb/Q9VYA4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 211, "end_pos": 213, "annotation": "n_glycosylation_sequon" }, { "start_pos": 279, "end_pos": 281, "annotation": "n_glycosylation_sequon" }, { "start_pos": 300, "end_pos": 302, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VYA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VYA4" }, { "id": "PF09468", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09468" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ribonuclease H2 subunit B wHTH", "eco_id": "ECO_0000259", "start_pos": 108, "end_pos": 238, "start_aa": "Phe", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q9VYA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VYA4" }, { "id": "PF17745", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17745" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rnh202 triple barrel", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 105, "start_aa": "Leu", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 211, "end_pos": 213 }, { "start_pos": 279, "end_pos": 281 }, { "start_pos": 300, "end_pos": 302 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 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OS=Drosophila melanogaster OX=7227 GN=tth PE=4 SV=1 CANONICAL=Q9VYA9-1" }, "isoforms": [ { "isoform_ac": "Q9VYA9-1", "url": "https://www.uniprot.org/uniprotkb/Q9VYA9/entry#Q9VYA9-1", "sequence": { "sequence": "MSSAVNIQIVSMPNLAKIESFLKDVSYRETIEYSANFNTRLCSERRHRLPFLDPQTGVAQNHSQLFLDKRQRMPGFRQGQIYTYPAARWRKSRRQYLSKMYSRFPERPFQALRKEHEALVASGVNLGLSSLTSGVGSMPGSNSLASSSSLTLNMLTGGGAAPAVLGSLHSDTAHDFNGAFSLEESSSLGAAGGDTSDSKDSQQQQHQQHQHQQQAVKEELLPKEWFYDDMDMNDVDSLEEPKSPADDEYDYDPRYGNKKRRKRRPGKRGGDSGGGGGGGGAGGGGNSGGSSSSRRRSAAARSRITTTDAALDASLEAIESGESVPGSNGGPISSGGILSGSLGAGLAGVSGSGGGGGASGASANSRRSRGAGTRGRRRAKGPNSAVGASCDPTSPGMVIEPPSFESAAAAVGVVEDANAHLRNYRKYL", "length": 428, "header": "tr|Q9VYA9-1|Q9VYA9_DROME Isoform 1 of Toothrin, isoform B OS=Drosophila melanogaster OX=7227 GN=tth PE=4 SV=1 CANONICAL=Q9VYA9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VYA9", "url": "https://www.uniprot.org/uniprotkb/Q9VYA9" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VYA9", "url": "https://www.uniprot.org/uniprotkb/Q9VYA9" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VYA9", "url": "https://www.uniprot.org/uniprotkb/Q9VYA9" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VYA9", "url": "https://www.uniprot.org/uniprotkb/Q9VYA9" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VYA9", "url": "https://www.uniprot.org/uniprotkb/Q9VYA9" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VYA9", "url": "https://www.uniprot.org/uniprotkb/Q9VYA9" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VYA9", "url": "https://www.uniprot.org/uniprotkb/Q9VYA9" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VYA9", "url": "https://www.uniprot.org/uniprotkb/Q9VYA9" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VYA9", "url": "https://www.uniprot.org/uniprotkb/Q9VYA9" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"NIPQMEE", "url": "https://omabrowser.org/oma/group/NIPQMEE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VYG4", "url": "https://www.orthodb.org/?gene=Q9VYG4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515:SF49", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515:SF49", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07776", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07776", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_572860", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572860", 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"MDSRMCRVCLREMENMLCIFETMPLPGVSLATMISDWCGFPVLPKDPFPKTICQSCALDAQTAYGMDSVQVIEQDEMVVSEMNYEEEGSNDSDVELIEPVDGSQEMETIDLTIDSPGDNVENMCPNSNSNGNGNVSQSSAQKDTKKKMLKKTHKCNICGKYFMLPAHLKCHMWVHAREKPYKCLQCSQSYAQIRGLRRHERVHSSRPELRSYKCSRCPKIFNRNSALKNHETMHHN", "length": 236, "header": "tr|Q9VYG4-1|Q9VYG4_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG4318 PE=4 SV=2 CANONICAL=Q9VYG4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VYG4", "url": "https://www.uniprot.org/uniprotkb/Q9VYG4" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VYG4", "url": "https://www.uniprot.org/uniprotkb/Q9VYG4" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VYG4", "url": "https://www.uniprot.org/uniprotkb/Q9VYG4" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VYG4", "url": "https://www.uniprot.org/uniprotkb/Q9VYG4" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VYG4", "url": "https://www.uniprot.org/uniprotkb/Q9VYG4" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VYG4", "url": "https://www.uniprot.org/uniprotkb/Q9VYG4" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VYG4", "url": "https://www.uniprot.org/uniprotkb/Q9VYG4" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VYG4", "url": "https://www.uniprot.org/uniprotkb/Q9VYG4" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VYG4", "url": "https://www.uniprot.org/uniprotkb/Q9VYG4" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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Learning difficulties and seizures may occur in childhood." }, { "id": "MONDO:0010028", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010028", "name": "sialuria", "description": "" }, { "id": "MONDO:0010028", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010028", "name": "sialuria, French type", "description": "" }, { "id": "MONDO:0011449", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011449", "name": "Salla disease", "description": "Salla disease is the mildest form of the free sialic acid storage disorders, which primarily affect the nervous system. Infants with Salla disease typically begin to experience poor muscle tone (hypotonia) during the first year of life,followed by slowly progressive neurological problems. Signs and symptoms include intellectual disability and developmental delay; seizures ; ataxia ; muscle spasticity; and involuntary slow movements of the limbs (athetosis). 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] }, { "id": "Q9VYG7-1", "url": "https://www.uniprot.org/uniprotkb/Q9VYG7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPPHKWTDESRDASCYYDPSTSSNSSASAERSDDEADDEREAFCSGERPLIRSSGAAEENHGCGPKTRHIFGFMGFLGFAVVYAMRVNLSVAIVAMVNQTAIPHSNSSVIDTDTCPLPAPHHNGSDPNPQKEGEFVWDEATQGLVLGSFFYGYVLTQVPGGRMAELYGGKKIYGYGVLITAVFTLITPLAAHWDLPLLVLVRILEGMGEGVTYPAMHAMLAHWIPPLERNKFAAIVYAGSNIGTVISMPLAGWLCSLDFLGGWPSAFYIFGLLGILWFIAWMYLVYDKPSDHPRISESEREYIERSLQVQRLINQDLAEAEEEEGQDEVSLRAPPEEPIPWSSLLTSVPLWAILLTQCGQGWAFYTQLTELPTYMSNILHFDIQSNALLNAVPYLTSWFVGIACSALADWMLARRYISLLNSYKLWNTVASVVPSLGLIGIIYVGCDWVWVTFMLAGVGSFGGAVYAGNQMNHIALSPRYAGTMYGITNSAANICGFLAPYVIGLIINHRETLTQWHLVFWLAAGLNIAGNFIYLIFASAEEQSWSKTPPTRNSRSQRA", "length": 559, "header": "tr|Q9VYG7-1|Q9VYG7_DROME Isoform 1 of Major facilitator superfamily transporter 10, isoform B OS=Drosophila melanogaster OX=7227 GN=MFS10 PE=4 SV=1 CANONICAL=Q9VYG7-1" }, "isoforms": [ { "isoform_ac": "Q9VYG7-1", "url": "https://www.uniprot.org/uniprotkb/Q9VYG7/entry#Q9VYG7-1", "sequence": { "sequence": "MPPHKWTDESRDASCYYDPSTSSNSSASAERSDDEADDEREAFCSGERPLIRSSGAAEENHGCGPKTRHIFGFMGFLGFAVVYAMRVNLSVAIVAMVNQTAIPHSNSSVIDTDTCPLPAPHHNGSDPNPQKEGEFVWDEATQGLVLGSFFYGYVLTQVPGGRMAELYGGKKIYGYGVLITAVFTLITPLAAHWDLPLLVLVRILEGMGEGVTYPAMHAMLAHWIPPLERNKFAAIVYAGSNIGTVISMPLAGWLCSLDFLGGWPSAFYIFGLLGILWFIAWMYLVYDKPSDHPRISESEREYIERSLQVQRLINQDLAEAEEEEGQDEVSLRAPPEEPIPWSSLLTSVPLWAILLTQCGQGWAFYTQLTELPTYMSNILHFDIQSNALLNAVPYLTSWFVGIACSALADWMLARRYISLLNSYKLWNTVASVVPSLGLIGIIYVGCDWVWVTFMLAGVGSFGGAVYAGNQMNHIALSPRYAGTMYGITNSAANICGFLAPYVIGLIINHRETLTQWHLVFWLAAGLNIAGNFIYLIFASAEEQSWSKTPPTRNSRSQRA", "length": 559, "header": "tr|Q9VYG7-1|Q9VYG7_DROME Isoform 1 of Major facilitator superfamily transporter 10, isoform B OS=Drosophila melanogaster OX=7227 GN=MFS10 PE=4 SV=1 CANONICAL=Q9VYG7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VYG7", "url": "https://www.uniprot.org/uniprotkb/Q9VYG7" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VYG7", "url": "https://www.uniprot.org/uniprotkb/Q9VYG7" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VYG7", "url": "https://www.uniprot.org/uniprotkb/Q9VYG7" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VYG7", "url": "https://www.uniprot.org/uniprotkb/Q9VYG7" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VYG7", "url": "https://www.uniprot.org/uniprotkb/Q9VYG7" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VYG7", "url": "https://www.uniprot.org/uniprotkb/Q9VYG7" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VYG7", "url": "https://www.uniprot.org/uniprotkb/Q9VYG7" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VYG7", "url": "https://www.uniprot.org/uniprotkb/Q9VYG7" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VYG7", "url": "https://www.uniprot.org/uniprotkb/Q9VYG7" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VYG7", "url": "https://www.uniprot.org/uniprotkb/Q9VYG7" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VYG7", "url": "https://www.uniprot.org/uniprotkb/Q9VYG7" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG4330", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG4330", "resource": "KEGG Pathway" }, { "id": "R-DME-2160916", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-2160916", "resource": "Reactome", "description": "Hyaluronan degradation" }, { "id": "R-DME-2672351", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-2672351", "resource": "Reactome", "description": "Stimuli-sensing channels" }, { "id": "R-DME-4085001", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-4085001", "resource": "Reactome", "description": "Sialic acid metabolism" }, { "id": "R-DME-427652", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-427652", "resource": "Reactome", "description": "Sodium-coupled phosphate cotransporters" }, { "id": "R-DME-428643", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-428643", "resource": "Reactome", "description": "Organic anion transport by SLC5/17/25 transporters" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JXU5-1", "protein_name": "Solute carrier family 17, member 4", "gene_name": "Slc17a4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSTGADLKAREGGIPNDSNLNMTQEQSFKKGCCSLRHGLAFILHLCNFSVYTQQMNLSIAITAMVNTTAASSHANASIERPTTDSQDFWNETLQESKAPVYDWTPEIQGILLSSLNYGSFLAPIPTGYVAGVFGAKYVVGLGLLVSSVLTLFIPLAAEAGVALLIVLRVIQGMSQVMVLTGQYSMWAKWAPPLERSQLITIAASGSMLGTFLVLIAGGLLCQALGWPYIFYIFGGIGCACCLLWFPLVYDDPQNHPFISTGEKRYIMCSLAQEDCSLGWSLPIKAMVKSLPLWAIVVSYFCEYWLLFTIMAYTPTYISSVLQANLRDSGILSALPFMFGCVCIILGGLLADFLLSRNILRLVTIRKLFTALGVLVSSGILVPLPWVSSSLSTTMAFLVLSSVFASLCDSGALINFLDIAPRYAGFLKGLLQVFSYLAGGIAPTVAGFFISQDSEFGWRNVFLLAAAIDVVGLLFYLIFGRAEVQDWAKEPTFTHL", "length": 495 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-060929-1158", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-1158#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": 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"database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "D4A3I8-1", "protein_name": "Solute carrier family 17, member 2", "gene_name": "Slc17a2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDEKPTTRKGSGFCSLRYALALVMHFSNFTMITQRVSLSIAIIAMVNSTQHQDPANASAEGPVMNLLSNRSRGIKDFSTRAAVYQWSTETQGIIFSSISYGIILTLIPSGYLAGIFGAKQILGAGLLISSLLTLFTPLAADFGVILVIVIRTVQGMAQGMSWTGQFTIWAKWAPPLERSKLTSIAGSGAAFGSFIILCVGGLISQALGWPFIFYIFGSIGCVCCVLWFTMIYDDPMHHPCISVKEKEYITSSVAQQSSSPRRSIPIKAMVRCLPLWAIFMGFFSHFWLCTIIITYLPTYISTVLHVNIRDSGVLSSLPFIAASSCTILGGQMADFLLSRNLLSLITVRKLFSSLGLLLPSLCAVALPFVTSSYIATIVLLILIPGTSNLCDSGFIINTLDVAPRYASFLMGISRGFGLTAGIISSTTTGFLISQVGHVIEHLQVAGF", "length": 447 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-060929-1158", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-1158#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9PTR8-1", "protein_name": "Solute carrier family 17 member 3", "gene_name": "Slc17a3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATVVELSPTSEQCEFVLGLPVNKKTPPRKVPSLCSMRYSIAFIAHICNFTLIAQNSIISITMVAMVNNTDQPSHLNSSTEWFPDGLNGDQHEASKHLSIKAPVYNWSPQTQGIIFSSVQYGMMLMQGPGGYLAGKLGTKKVVGIALLGSSLLTLCIPLAANLGLAFLLATRAVQGLTQGAGYGGQFALWQKWAPPNERSRLCSIAMSGMILGIFAVLLVGGIISEALGWPFVFYIFGSIGVVCCLLWLILVYDDPVSHPWISSPEKEYILSSLDQQFNSEEQPLPIKAMLKSLPLWSMCLCSMTHQWLVNTLIIYTPTYISSVFKVNIRDNGLLSSLPFFVAWVIGILGGLLADFLLSKNFRLITVRKIITILGNTPPAALVVALPYVQSSYIATTTFLTLSCGLSPLCQSGVYINALDIAPRYASLLMGTSRGLAHSSAVMVPIVAGFFLNQDSEFGWRNFFFVLFAINLFGLIIYLVFAKADIQEWARERKLTRL", "length": 498 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-060929-1158", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-1158#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P15365-1", "protein_name": "Allantoate permease", "gene_name": "DAL5", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSADASTNSNASLDEKNLNITSEAEIKNEDVTAEPVLSTVLSPNGKIVYISDKVDEAMKLAEEAKEIEVTPEEDRKLRWKIDYCMFPLMCILYAVQFMDKISTSSAAVMGLRTDLKMHGDQYSWVTSAFYFGYLFMNLGPVQFIFQRTSHMSKMLAVFIVIWGMLLALHAAPTVKYPSFIVLRVLLGCAESVVTPCFTIITAQYWKTEEQFTRVSIWFGMNGLGSILINAIAYGVYIHQDSYAIKGWRTLFVITGVITIFIGILIFLWIPDDPSKARFLSKREKLMVVQRIRSNQQGFGNHEIKKYQIIEALKDVRTWLYFLFTVSSNIPNGGISSFMSILLNSDFGYSSKETLLMGLPTGAVELVGCPLFGILAVYAANKKIPFWKYKLSWAIFAAVLALIASCMLGFATNSKKARLAGAYLWYISPVSFICVLSNISANSSGYSKKWTVSSINLVAYAAANLAGPQTFIAKQAPKYHGAKVAMVVCYAVMIVLLSILLIVNLRENKRRDKIAAERGFPEETENLEFSDLTDFENPNFRYTL", "length": 543 }, "evidence": [ { "id": "FB:FBgn0030452", "url": "https://alliancegenome.org/gene/FB:FBgn0030452#orthology", "database": "AGR" }, { "id": "SGD:S000003913", "url": "https://alliancegenome.org/gene/SGD:S000003913#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P25621-1", "protein_name": "Pantothenate transporter FEN2", "gene_name": "FEN2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MMKESKSITQHEVERESVSSKRAIKKRLLLFKIDLFVLSFVCLQYWINYVDRVGFTNAYISGMKEDLKMVGNDLTVSNTVFMIGYIVGMVPNNLMLLCVPPRIWLSFCTFAWGLLTLGMYKVTSFKHICAIRFFQALFESCTFSGTHFVLGSWYKEDELPIRSAIFTGSGLVGSMFSGFMQTSIFTHLNGRNGLAGWRWLFIIDFCITLPIAIYGFIFFPGLPDQTSAVSKFSMTRYIFNEQELHYARRRLPARDESTRLDWSTIPRVLKRWHWWMFSLVWVLGGENLGFASNSTFALWLQNQKYTLAQRNNYPSGIFAVGIVSTLCSAVYMSKIPRARHWHVSVFISLVMVIVAVLIRADPLNPKVVFSAQYLGGVAYAGQAVFFSWANIICHADLQERAIVLASMNMFSGAVNAWWSILFFASDMVPKFERGCYALLATAISSGIVSVVIRSLQIKENLSKKQVPYIDANDMPGEDDDDDNQDNENDGDDESMEVELHNEEMAEISNPFR", "length": 512 }, "evidence": [ { "id": "MGI:1924105", "url": "https://alliancegenome.org/gene/MGI:1924105#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P39709-1", "protein_name": "Probable transporter SEO1", "gene_name": "SEO1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MYSIVKEIIVDPYKRLKWGFIPVKRQVEDLPDDLNSTEIVTISNSIQSHETAENFITTTSEKDQLHFETSSYSEHKDNVNVTRSYEYRDEADRPWWRFFDEQEYRINEKERSHNKWYSWFKQGTSFKEKKLLIKLDVLLAFYSCIAYWVKYLDTVNINNAYVSGMKEDLGFQGNDLVHTQVMYTVGNIIFQLPFLIYLNKLPLNYVLPSLDLCWSLLTVGAAYVNSVPHLKAIRFFIGAFEAPSYLAYQYLFGSFYKHDEMVRRSAFYYLGQYIGILSAGGIQSAVYSSLNGVNGLEGWRWNFIIDAIVSVVVGLIGFYSLPGDPYNCYSIFLTDDEIRLARKRLKENQTGKSDFETKVFDIKLWKTIFSDWKIYILTLWNIFCWNDSNVSSGAYLLWLKSLKRYSIPKLNQLSMITPGLGMVYLMLTGIIADKLHSRWFAIIFTQVFNIIGNSILAAWDVAEGAKWFAFMLQCFGWAMAPVLYSWQNDICRRDAQTRAITLVTMNIMAQSSTAWISVLVWKTEEAPRYLKGFTFTACSAFCLSIWTFVVLYFYKRDERNNAKKNGIVLYNSKHGVEKPTSKDVETLSVSDEK", "length": 593 }, "evidence": [ { "id": "MGI:1924105", "url": "https://alliancegenome.org/gene/MGI:1924105#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P40445-1", "protein_name": "Uncharacterized transporter YIL166C", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSVQKEEYDIVEKAQLSVSAESLTSDSESISHNPFDDFHKAERWRKVYESSGYEGLSKFDPEFTWTKDEEKKLVRKMDLKIFLWVFIMFAFLDLIRKNIARAVSDNFIVDLKMNTNDYNLGQTVYLVIFLASELPGNLLSKRFGPERVIPVQIVLWSVICITQAGLKNRGQFIATRCLLGMVQGGFIPDNILYLSYYYTGAELTFRLSFFWCAIPLFQILGSLLASGIIEMRGIHNLAGWQYLFIIEGFLSLSVGVASFYLMRRGPTQTGESAFHKGKSLFTEYEEKIMVNRILRDDPSKGDMSNRQPVTFKEILYTLTEFDLWPLFIQGITAFISLQTVGSYLSLILKSLNYSTFLSNILAIPGQALLLINLPLAALLSRKLKEKSLCVGIANVWVLPFIVSLVALPTDTNPWIKYILLTGILGLPYTHSILAGWVSEISNSVRSRTVGTALYNMSAQVGAIIASNMYRNDDKPYYTRGNKILLGFTCFNICMAVATKFYYISRNKYKDRKWNSMTKEEQINYLDTTKDKGMKRLDYRFIH", "length": 542 }, "evidence": [ { "id": "FB:FBgn0030452", "url": "https://alliancegenome.org/gene/FB:FBgn0030452#orthology", "database": "AGR" }, { "id": "SGD:S000001428", "url": "https://alliancegenome.org/gene/SGD:S000001428#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P53241-1", "protein_name": "Vitamin H transporter", "gene_name": "VHT1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTISNKSWRSYFPHLRKLPEDDQYLYSDDTNSSIIAEEELHHSVDKSSKTDVTAETTAVEPHPHNLRHDLPYEVRDEAGRKWWKYFDEFEYRVNKEYKKSRKWYEFLYPNHTTQTKAERRLLYKLDIIIALYFFMLCWSKSVDLNNYTNAYVSNMKEDLNMKGNDYVYTSTIANVGAIVFQLPFMYLLPRFPSHIILPVMDLGWTWFTFACYRANSLAELRAYRFILSAFGAAYYPVSQYILGCWYAPDEINSRVCLFFCGQQLGSVTSGLLQSRIFKSLNGVHGLAGWRWMFLIDAIAISLPTAIIGFFVIPGVPSKCYSLFLTDEEIRIARARNKRNQIKDGVDKSKLAPLWSRKLWKKVFCTPAFWVLVVFDTCSWNNMTAYSGSYTLWLKSNTKYSIAQVNNLSVIPACLGFAYVIFCAFGADLFRCKWIFMVFAAIMNTVSCALLIKWDIPSKAKWYAFFTTYFSVAASPCLWSFINDFLRFDPQVKAITWIAIYSFSQSTYAWIPTLAWPTVESPRFKTGYTVSLIFGAIYGLWTFVVLFFYKRNEKKHALGNGIILYDSNKGEELPEFVKKNMEERDGYYYLKRSS", "length": 593 }, "evidence": [ { "id": "MGI:1924105", "url": "https://alliancegenome.org/gene/MGI:1924105#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P53322-1", "protein_name": "High-affinity nicotinic acid transporter", "gene_name": "TNA1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSNKFTMESPKHLVDDVLFISPTNDGSEEKPTEVTFQEDEGHDASLHNRSHDKKSELATEREIMATTTDDDGIPSPSHPMEKRVLRKMDIYLIPLMGMLYFLSNLDKSNIGNAEVAGLSKDIHLVGTQYNTCVTVFFATYVLFDPIGTNLLKIMGPPLMMSICLTCFGAISLGTAWVKNYAQLIVVRLLLGAFEGMIYPAINMYLSVCYRREQYALRFAFVFSAACLSSSFGGLIAYGCSKISGSLKDWQYIYIVEGCISLGFVPFYAFGLSKNLEDSWFFNKEEKEYISERYKTMNTFDPDEKFEWFQVWQAVKDVKTWASAVALFGIDLTTFGLTVFLPIIITSMGFTNVRAQLMTVPIYFLTAIVFFICAVWSDRIKLRSPFILGACLTTSIGIAIVLGSQVHGVRYFGVYILCMGIYVNAACNCLWLSGNTGNYFKRATALGINLFFGSGSGLVSGQIFVAKDKPRYIKGLSISLAFQVFSIFMTVVQIFLYKRENDKKKAIIDRCNELGEPIPYDERLSDKNPEFKYMY", "length": 534 }, "evidence": [ { "id": "MGI:1924105", "url": "https://alliancegenome.org/gene/MGI:1924105#orthology", "database": "AGR" }, { "id": "HGNC:10933", "url": "https://alliancegenome.org/gene/HGNC:10933#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060929-1158", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-1158#orthology", "database": "AGR" }, { "id": "FB:FBgn0030452", "url": "https://alliancegenome.org/gene/FB:FBgn0030452#orthology", "database": "AGR" }, { "id": "SGD:S000003492", "url": "https://alliancegenome.org/gene/SGD:S000003492#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q07904-1", "protein_name": "Thiamine pathway transporter THI73", "gene_name": "THI73", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MKNMSQRSMDVEKKAANADSCSVSTSSINVDDADVALRFLKQNGLDESSTANEDDVVAGEEANFYGSHELSPKVLRKVDLFILPFLCCTYLLMFLDKALLNYAASMGIKDHLKGNEFSNLGTIFSAAYIFMEPVVTYLIQKFPISKILGTFITVWGIVLACHAACKTYASLMVVRTLLGLFESSSAVGCIAISGMYYTKSEQSARIGFWATQAGTGYIVGGLISFGFLHYHGTAFTSWQIMFLVVGLVTVAFGVLTFLYLPDNVTNAWFLNKEEKIQVVEHIRANQTGLETKKFKKQQVKELFLHDKFTWPMLLLTACSQISTGAIGTFSVTITGTFGFDKYETALLQLPIGAITAMIILITTQMLSRWGHITLITTSMYIPAIIGCIVLISLPLSHKIGNLFSLYLLYSGSCVITNIYIWNSCNTSGYTKRVFRNAITMIVYNVSCIIAPQMFRAYSAPRYIPAKIALLVTQCVCVPLQLYIGYICKKENEKRDKEQEGQERKKYQFLDLTDIENRNFRYIY", "length": 523 }, "evidence": [ { "id": "FB:FBgn0030452", "url": "https://alliancegenome.org/gene/FB:FBgn0030452#orthology", "database": "AGR" }, { "id": "SGD:S000003994", "url": "https://alliancegenome.org/gene/SGD:S000003994#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q1L8X9-1", "protein_name": "Vesicular glutamate transporter 3", "gene_name": "slc17a8", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPLGGFAGLKEKLNPGKEELKNNVGDSLGNLQKKIDGSNVTEEDNIELTEDGRPVAAPKRSPPLLDCGCFGLPKRYIIAMLSGLGFCISFGIRCNLGVAIVEMVNNNTVYINGTAVMQPAQFNWDPETVGLIHGSFFWGYIVTQIPGGFISNKLAANRVFGAAIFLTSVLNMFIPSAARVHYGCVMFVRILQGLVEGVTYPACHGMWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQYVGWPSVFYIYGVFGIIWYIFWILLAYNSPAVHPTISEEERNYIETSIGEGANLMSSTEKFKTPWREFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFPISKVGILSAVPHMVMTIIVPIGGQLADFLRSRKILSTTTVRKIMNCGGFGMEATLLLVVGFSHTRAVAISFLILAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPLIVGALTKHKTRLEWQHVFVIASMVHYTGVIFYAIFASGEKQDWADPENTSDEKCGIIGEDELADETEPSSDSGLATRQKTYGTTDNSSGRKQGWKKKRGVTMQAEDDHESNHYENGEYQTQYQ", "length": 590 }, "evidence": [ { "id": "SGD:S000003913", "url": "https://alliancegenome.org/gene/SGD:S000003913#orthology", "database": "AGR" }, { "id": "SGD:S000003994", "url": "https://alliancegenome.org/gene/SGD:S000003994#orthology", "database": "AGR" }, { "id": "SGD:S000001428", "url": "https://alliancegenome.org/gene/SGD:S000001428#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5Q0U0-1", "protein_name": "Sialin", "gene_name": "Slc17a5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRPLLRGPAGNDDEESSDSTPLLPSARQIEAAPACCSARYNLALLAFCGFFVLYALRVNLSVALVDMVDSNSTLTDNRTSKECAEHSAPVKVHHNHTGKKYQWDAETQGWILGSFFYGYIVTQIPGGYMASRIGGKLLLGLGILGTAVFTLFTPLAADLGVVALIVLRALEGLGEGVTFPAMHAMWSSWAPPLERSKLLTISYAGAQLGTVISLPLSGIICYYMNWTYVFYLFGLVGIVWFILWMWIVSDTPETHKTISHYEKEYIVSSLKNQLSSQKVVPWVSILKSLPLWAIVVAHFSYNWTFYTLLTLLPTYMKEILRFNVQENGFLSALPYFGCWLCMIVCGQAADYLRVKWNFSTISVRRIFSLIGMVGPAVFLVAAGFIGCDYSLAVAFLTISTTLGGFASSGFSINHLDIAPSYAGILLGITNTFATIPGMIGPIIAKSLTPDNTIKEWQTVFCIAAAINVFGAIFFTLFAKGEVQNWALSDHHGHGN", "length": 495 }, "evidence": [ { "id": "HGNC:10933", "url": "https://alliancegenome.org/gene/HGNC:10933#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5W8I7-1", "protein_name": "Vesicular glutamate transporter 2.2", "gene_name": "slc17a6a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDTVKERVLAPGKEKMRNLAGKTLGHMHRVMERKQKTGEVIELTEDGRPMHMPEKKAPLVDCTCFGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVDMVNNSTIHKGGKIIIKGKAKFNWDPETVGMIHGSFFWGYTVTQIPGGYISSRLAANRVFGAAILLTSTLNMFIPSAARVHYGCVMFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTSFCGSYAGAVVAMPLAGILVQYSGWSSVFYIYGSFGIVWYMFWILVSYESPADHPTITDEERTYIEESIGESAKLLGAMEKYKTPWRKFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGMVSALPHLVMTIIVPIGGQLADYLRSKNILTTTTVRKIMNCGGFGMEATLLLVVGFSHSKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPLIVGAMTKNKTREEWQNVFLIASLVHYGGVIFYGIFASGEKQPWADPEETSDEKCGFIDEDELAEETGDITLSHAPFGAQGALGAPAKTYGATTQLNGGWAKGWEKTEEFIQEDAERTYTGDGYS", "length": 587 }, "evidence": [ { "id": "SGD:S000003913", "url": "https://alliancegenome.org/gene/SGD:S000003913#orthology", "database": "AGR" }, { "id": "SGD:S000003994", "url": "https://alliancegenome.org/gene/SGD:S000003994#orthology", "database": "AGR" }, { "id": "SGD:S000001428", "url": "https://alliancegenome.org/gene/SGD:S000001428#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5W8I8-1", "protein_name": "Vesicular glutamate transporter 2.1", "gene_name": "slc17a6b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "METPREPAGFSKEGLKQLAGKTLGHVYRVIEKRQKPGENIELTEDGRPAQINERKAPLCDCTCFGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVSMVNNSTIHLNGKIIIKEKAKFNWDPETVGLIHGSFFWGYIVTQIPGGYISSRLAANRVFGAAILLTSTLNMFIPSAARGHYGCVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQYTGWSSVFYVYGCFGIFWYMFWILVSYESPAEHPTITAEERCYIEESIGESAKLLGPADKFKTPWRKFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGMLSALPHLVMTIIVPIGGQLADHLRSKNILSTTTVRKIMNCGGFGMEATLLLIVGYSHSKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPLIVGAMTKHKTREEWQYVFLIASLVHYGGVIFYGIFASGEKQPWADPELTSDEKCGFIDEDELAEETGDITQSYGALGAPAKSYGATTQLNGGWAEGWDKREEYVQDGVEEGGYGYRQGGNYS", "length": 584 }, "evidence": [ { "id": "SGD:S000003913", "url": "https://alliancegenome.org/gene/SGD:S000003913#orthology", "database": "AGR" }, { "id": "SGD:S000003994", "url": "https://alliancegenome.org/gene/SGD:S000003994#orthology", "database": "AGR" }, { "id": "SGD:S000001428", "url": "https://alliancegenome.org/gene/SGD:S000001428#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q62795-1", "protein_name": "Sodium-dependent phosphate transport protein 1", "gene_name": "Slc17a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MENRCLPKKVPGFCSFRYGLAILLHFCNIVIMAQRVCLNLTMVAMVNKTEPPHLSNKSVAEMLDNVKNPVHSWSLDIQGLVLSSVFLGMVVIQVPVGYLSGAYPMEKIIGSSLFLSSVLSLLIPPAAQVGAALVIVCRVLQGIAQGAVSTGQHGIWVKWAPPLERGRLTSMTLSGFVMGPFIALLVSGFICDLLGWPMVFYIFGIVGCVLSLFWFILLFDDPNNHPYMSSSEKDYITSSLMQQVHSGRQSLPIKAMLKSLPLWAIILNSFAFIWSNNLLVTYTPTFISTTLHVNVRENGLLSSLPYLLAYICGIVAGQMSDFLLSRKIFSVVAVRKLFTTLGIFCPVIFVVCLLYLSYNFYSTVIFLTLANSTLSFSFCGQLINALDIAPRYYGFLKAVTALIGIFGGLISSTLAGLILNQDPEYAWHKNFFLMAGINVTCLAFYLLFAKGDIQDWAKETKTTRL", "length": 465 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-060929-1158", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-1158#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BN82-1", "protein_name": "Sialin", "gene_name": "Slc17a5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRPLLRGPAGNDDEESSDSTPLLPGARQTEAAPVCCSARYNLAILAFCGFFVLYALRVNLSVALVDMVDSNTTLTDNRTSKECAEHSAPIKVHHNHTGKKYKWDAETQGWILGSFFYGYIVTQIPGGYIASRVGGKLLLGLGILGTSVFTLFTPLAADLGVVTLVVLRALEGLGEGVTFPAMHAMWSSWAPPLERSKLLTISYAGAQLGTVISLPLSGIICYYMNWTYVFYLFGIVGIVWFILWMWIVSDTPETHKTISHYEKEYIVSSLKNQLSSQKVVPWGSILKSLPLWAIVVAHFSYNWSFYTLLTLLPTYMKEILRFNVQENGFLSALPYFGCWLCMILCGQAADYLRVKWNFSTISVRRIFSLVGMVGPAVFLVAAGFIGCDYSLAVAFLTISTTLGGFASSGFSINHLDIAPSYAGILLGITNTFATIPGMTGPIIAKSLTPDNTIREWQTVFCIAAAINVFGAIFFTLFAKGEVQSWALSDHHGHRN", "length": 495 }, "evidence": [ { "id": "MGI:1924105", "url": "https://alliancegenome.org/gene/MGI:1924105#orthology", "database": "AGR" }, { "id": "HGNC:10933", "url": "https://alliancegenome.org/gene/HGNC:10933#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060929-1158", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-1158#orthology", "database": "AGR" }, { "id": "FB:FBgn0030452", "url": "https://alliancegenome.org/gene/FB:FBgn0030452#orthology", "database": "AGR" }, { "id": "SGD:S000003492", "url": "https://alliancegenome.org/gene/SGD:S000003492#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8GX78-1", "protein_name": "Ascorbate transporter, chloroplastic", "gene_name": "PHT4;4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MALGGLISNRNFGSFIGSGNGCQRLGKSGAEVSKLFPNALLCRNHQPLQASLHHESGHMRRSFGCFLQPRMDSVIRFRNSIKINRSRAYYKSEESDITEGVVPSADGSAEAILVEGNLQNASPWWQQFPRRWVIVLLCFSSFLLCNMDRVNMSIAILPMSQEYNWSSATVGLIQSSFFWGYLLTQILGGIWADKFGGKVVLGFGVVWWSFATIMTPIAARLGLPFLLVVRAFMGIGEGVAMPAMNNMLSKWIPVSERSRSLALVYSGMYLGSVTGLAFSPMLITKFGWPSVFYSFGSLGSIWFLLWLKFAYSSPKDDPDLSEEEKKVILGGSKPREPVTVIPWKLILSKPPVWALIISHFCHNWGTFILLTWMPTYYNQVLKFNLTESGLLCVLPWLTMAVFANIGGWIADTLVSRGLSITNVRKIMQSIGFLGPAFFLSQLSHVKTPAMAVLCMACSQGSDAFSQSGLYSNHQDIGPRYAGVLLGLSNTAGVLAGVFGTAATGYILQRGSWDDVFKVAVALYLIGTLVWNLFATGEKILD", "length": 541 }, "evidence": [ { "id": "Q9VYG7", "url": "https://omabrowser.org/oma/group/Q9VYG7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9NRA2-1", "protein_name": "Sialin", "gene_name": "SLC17A5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRSPVRDLARNDGEESTDRTPLLPGAPRAEAAPVCCSARYNLAILAFFGFFIVYALRVNLSVALVDMVDSNTTLEDNRTSKACPEHSAPIKVHHNQTGKKYQWDAETQGWILGSFFYGYIITQIPGGYVASKIGGKMLLGFGILGTAVLTLFTPIAADLGVGPLIVLRALEGLGEGVTFPAMHAMWSSWAPPLERSKLLSISYAGAQLGTVISLPLSGIICYYMNWTYVFYFFGTIGIFWFLLWIWLVSDTPQKHKRISHYEKEYILSSLRNQLSSQKSVPWVPILKSLPLWAIVVAHFSYNWTFYTLLTLLPTYMKEILRFNVQENGFLSSLPYLGSWLCMILSGQAADNLRAKWNFSTLCVRRIFSLIGMIGPAVFLVAAGFIGCDYSLAVAFLTISTTLGGFCSSGFSINHLDIAPSYAGILLGITNTFATIPGMVGPVIAKSLTPDNTVGEWQTVFYIAAAINVFGAIFFTLFAKGEVQNWALNDHHGHRH", "length": 495 }, "evidence": [ { "id": "MGI:1924105", "url": "https://alliancegenome.org/gene/MGI:1924105#orthology", "database": "AGR" }, { "id": "HGNC:10933", "url": "https://alliancegenome.org/gene/HGNC:10933#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060929-1158", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-1158#orthology", "database": "AGR" }, { "id": "FB:FBgn0030452", "url": "https://alliancegenome.org/gene/FB:FBgn0030452#orthology", "database": "AGR" }, { "id": "SGD:S000003492", "url": "https://alliancegenome.org/gene/SGD:S000003492#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9V7S5-1", "protein_name": "Putative inorganic phosphate cotransporter", "gene_name": "Picot", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPFRRSSLNHRHRDGHVLVWNQRNLHESLEQQPQRCFATRYFVTFMLFLGMANAYVMRTNMSVAIVAMVNHTAIKSGEAEEYDDECGDRDIPIDDSQDGEFAWSSALQGYILSSFFYGYVITQIPFGILAKKYGSLRFLGYGMLINSVFAFLVPVAARGGGVWGLCAVRFIQGLGEGPIVPCTHAMLAKWIPPNERSRMGAAVYAGAQFGTIISMPLSGLLAEYGFDGGWPSIFYVFGIVGTVWSIAFLIFVHEDPSSHPTIDEREKKYINDSLWGTDVVKSPPIPFKAIIKSLPFYAILFAHMGHNYGYETLMTELPTYMKQVLRFSLKSNGLLSSLPYLAMWLFSMFISVVADWMISSKRFSHTATRKLINSIGQYGPGVALIAASYTGCDRALTLAILTIGVGLNGGIYSGFKINHLDLTPRFAGFLMSITNCSANLAGLLAPIAAGHLISDPSKPMMGQWQIVFFIAAFVYIICGTFYNIFGSGERQYWDNPEDDEQKPALQTTVTTSPARLSNGSTAPAAISSS", "length": 529 }, "evidence": [ { "id": "MGI:1924105", "url": "https://alliancegenome.org/gene/MGI:1924105#orthology", "database": "AGR" }, { "id": "HGNC:10933", "url": "https://alliancegenome.org/gene/HGNC:10933#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060929-1158", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-1158#orthology", "database": "AGR" }, { "id": "SGD:S000003492", "url": "https://alliancegenome.org/gene/SGD:S000003492#orthology", "database": "AGR" }, { "id": "SGD:S000003913", "url": "https://alliancegenome.org/gene/SGD:S000003913#orthology", "database": "AGR" }, { "id": "SGD:S000003994", "url": "https://alliancegenome.org/gene/SGD:S000003994#orthology", "database": "AGR" }, { "id": "SGD:S000001428", "url": "https://alliancegenome.org/gene/SGD:S000001428#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VJW8-1", "protein_name": "Major facilitator superfamily (MFS) profile domain-containing protein", "gene_name": "Dmel\\CG9254", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MADAKEQPEWGIKLSKFFVLPQRWILAIMGFFAIFNAYTMRICLSQAITVLVVKRNYTIFHTEAICEPDDQSDPSSTFEGGDYDWSQEKQGLILASFYIGYIVTHLPGGILADKFGGKWTLSLGIFFTAIFTLLTPVCIVYGGADALIVLRVLMGLGEGTTFPALSVLLASWVPANERGMLGALVLGGGQMGSIAGNIISGYVLSSMDWPWVFYVFAIIALVWFVVFTLVCFSSPFTHPYIKPEERAFLAQEVPPPDKNKPKTPFFAILTSIPMWALISAQIGHDWGFYIMVSYLPKYMSDVLRFSIKSNGLYSSLPYVTMWIMSLLSGCVADQMIKRNCMSTTNTRKIMTGVAAFGPAVFMVAASYAGCNRGMVVALFTITMGLMGTYYAGMKLTPLDMSPNYAGTLMAITNGIGAITGVVSPYLVGVMTPNATLLEWRLVFWVAFGVLVVTAIVYCIWASGDVQPFNDGTNSNKKKDAA", "length": 481 }, "evidence": [ { "id": "SGD:S000003492", "url": "https://alliancegenome.org/gene/SGD:S000003492#orthology", "database": "AGR" }, { "id": "SGD:S000003913", "url": "https://alliancegenome.org/gene/SGD:S000003913#orthology", "database": "AGR" }, { "id": "SGD:S000003994", "url": "https://alliancegenome.org/gene/SGD:S000003994#orthology", "database": "AGR" }, { "id": "SGD:S000001428", "url": "https://alliancegenome.org/gene/SGD:S000001428#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VKC9-1", "protein_name": "Dietary and metabolic glutamate transporter", "gene_name": "dmGlut", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTQQPQWGISLSRYFVIPQRVILAIMGFLAILNAYTMRVCLSQAITVLVVKKNSTDDDSEAICEPDDIDEGTSVGGDFEWSEELQGLILSSFYIGYIVTHIPGGLLAEKFGGKWTLGLGILSTAVFTMLTPLAINKGDSDWLIVTRVLMGLGEGTTFPALSVLLAAWVPANERGKLGALVLGGGQVGTIMGNLLSGVFIDAYGWEFVFYFFGGLGVVWFAIFMFLCYSDPTSHPFIKPSEREYLVKEIGTISRNEDLPPTPWKAILTNLPMFALVAAQIGHDWGFYIMVTDLPKYMADVLQFSIKANGLYSSLPYVMMWIVSVGSGFVADWMIRRGVLSTTNTRKVMTGLAAFGPAIFMVGASYAGCDRVLVVVLFTICMGLMGAYYAGMKLSPLDMSPNYAGTLMAITNGIGAITGVITPYLVGVMTPNASLLEWRLVFWVAFGVLCFTAVIYCIWASGEVQPFNNAPIQPRSVDFEAQERKVGGEKTSGLEQSS", "length": 496 }, "evidence": [ { "id": "SGD:S000003492", "url": "https://alliancegenome.org/gene/SGD:S000003492#orthology", "database": "AGR" }, { "id": "SGD:S000003913", "url": "https://alliancegenome.org/gene/SGD:S000003913#orthology", "database": "AGR" }, { "id": "SGD:S000003994", "url": "https://alliancegenome.org/gene/SGD:S000003994#orthology", "database": "AGR" }, { "id": "SGD:S000001428", "url": "https://alliancegenome.org/gene/SGD:S000001428#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VPX2-1", "protein_name": "Major facilitator superfamily transporter 3", "gene_name": "MFS3", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTDEVPAKGSILGKLVPARYVLALLGSIGMAIVYGLKVNLSVAMVAMVNHTAIKAHGDGGGHGGHGSVILSNASQVSLVEECNPPGGASNVTAKVEDGPFDWSEPLQGTLLSCYFWGYLVSQIPLAHVAENFSAKWVMLFSVAINVVCTLLTPVFTELHYGGLILMRVLEGVGGGASFPAMHVMIASWAPPTERMVMSTIIYVGTSAGTALSILLAGVCSAQWGWESVFYVMGALSCIWMLLWVILVQDNPNKQRFISLEERQMITSSLGTEQKTEHHPAVPWGKVFTSVPFWAILIAHTCSNFGWYMFLIEIPFYMKQVLKFNVASNAALSALPYFPMIIFSICLGKLLDSLQAKGKITTTVARKTATSICTLIPGVCLLVLCYIGCRHYEAVSVMSVGIVAMGSMFSGFLSNHIDIAPNFAGTLVALTNTAATLPGIVVPLFVGFVTKGNQNIGAWRIIFGVTIVLFALEFLVFVFLGSGSEQPWNKAGTPKDPEAKDEKTPLKELPTKP", "length": 512 }, "evidence": [ { "id": "SGD:S000003492", "url": "https://alliancegenome.org/gene/SGD:S000003492#orthology", "database": "AGR" }, { "id": "SGD:S000003913", "url": "https://alliancegenome.org/gene/SGD:S000003913#orthology", "database": "AGR" }, { "id": "SGD:S000003994", "url": "https://alliancegenome.org/gene/SGD:S000003994#orthology", "database": "AGR" }, { "id": "SGD:S000001428", "url": "https://alliancegenome.org/gene/SGD:S000001428#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VQC0-1", "protein_name": "Vesicular glutamate transporter, isoform A", "gene_name": "VGlut1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKGLTAFKEKATGVFGGLKPNMEKFEISQSYHGGHGGYEEMEGGDREGRGPGGGHAYDDDDDRPDSPASFEEIERPPLRKIDKYCKAECPCMPARYTIATMACVGFMIAFGMRCNMSAAKLKGEHNGTVFMNWTVAVESHVDSSFFWGYLVTQIPGGFIASKFPANKIFGLSIVSSATLHLFVPFAMTLMHGHVVICVRVLQGLFEGVTYPACHGIWRFWAPPMERSRLATLAFSGSYAGVVVGLPLSGLLADAVGYQAPFYAYGVFGIIWYMFWIWLCFENPRKHPAISIPELKYIEKSLGESAHPTMPSLKTTPWREMMRSMPVYAIIVANFCRSWNFYLLVLFQSSFLKHKFGFKVEEAGFVGSLPHLIMTTIVPFGGMLADHLRKNGILSTTNVRKLFNCGGFGMEGLFFLFVAHSSTATGAMFALTCGVAFSGFAISGYNVNHLDIAPRYASILMGLSNGIGTLAGIIVPYALDGLIQANPTGCWTTVFTLAACVHLVGCTFYGIFASGELQPWAEPPAEEQKVWAPPPGAITNTDPSQAGMLGDYMKETSFGAPEYTEQSQMQQSTAISYGATGHVANNPFAMASGAPPIAEEDAPPTYGDVTNPGQYGYTQGQMPSYDPQGYQQQ", "length": 632 }, "evidence": [ { "id": "SGD:S000003492", "url": "https://alliancegenome.org/gene/SGD:S000003492#orthology", "database": "AGR" }, { "id": "SGD:S000003913", "url": "https://alliancegenome.org/gene/SGD:S000003913#orthology", "database": "AGR" }, { "id": "SGD:S000003994", "url": "https://alliancegenome.org/gene/SGD:S000003994#orthology", "database": "AGR" }, { "id": "SGD:S000001428", "url": "https://alliancegenome.org/gene/SGD:S000001428#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VR44-1", "protein_name": "Major facilitator superfamily (MFS) profile domain-containing protein", "gene_name": "CT10168", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSNTEKGGLQRVRNFLSCRQVLNLLTMLGFMLNYALRVNLTIAIVDMVRPNVTSAVNATLVGNSTAANSTASPDGVDVYEERFPWDSYQTNFVLGCFFWGYILTELPGGRLAELIGGRRVFGHSMLWASLLTLITPLAAHINYVVLIVVRVVLGFMLGASWPAIHPVAAVWIPPMERSKFMSNMMASSLGAAITMPICGYLISVAGWASVFYLTGAVGLLWSLAWFTFVYETPATHPRISAEERREIEEAIGTTTSKKRPSHVPWGQLLCSPAVWAIIICHGLAVFGFFTVVNQLPTFMSKILHFDIKQNGLFSSLPYLGKYVMAVASSYLADYLRKKGTLSTTATRKLFTTFALVIPGLLMIVQVFLGYDATWSVTIFSLALFAHGAVTAGYLGNGLDIAPNFGGTIFGLANTLSSFGGFLSTSMVGALTYKDQSFHSWQIVFWILAATYISAAVVFAILGSGELQPWNNPPERVRISDVTQEEGVPLKNEK", "length": 493 }, "evidence": [ { "id": "SGD:S000003492", "url": "https://alliancegenome.org/gene/SGD:S000003492#orthology", "database": "AGR" }, { "id": "SGD:S000003913", "url": "https://alliancegenome.org/gene/SGD:S000003913#orthology", "database": "AGR" }, { "id": "SGD:S000003994", "url": "https://alliancegenome.org/gene/SGD:S000003994#orthology", "database": "AGR" }, { "id": "SGD:S000001428", "url": "https://alliancegenome.org/gene/SGD:S000001428#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W4G7-1", "protein_name": "Putative inorganic phosphate cotransporter", "gene_name": "Dmel\\CG6978", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTDTAGVYDSKGVSNRNRSDQEVRMERYASDGQIPRCRKTRFFVVLMLFSGMANAYVMRTNMSVAIVAMVNHTAISHTKSSTQSKERDGDFEWSYKLQGYILSSFFYGYVITQIPFGLMIKYYGARHFLGWGMMINSLAAFFIPISARSGGVVGLCVVRFIQGLGEGPIVPCSHSLLAQWVPPNERSLAGAAVYAGAQFGTIVSMPLSGLLAHYGFDGGWPSIFYIFGLFSTIWCIIFICLVQESPAVSTRISEAERRHIMEAIWQAQPEERSRIPFLGIAKSPPFYAILVAHAGHNYGYETLMTMLPTYMYRVLNVNIRTNGIISSLPYLAMWILAIVFGILADCLIRRNFSITVVRKLMNSLGQYGPAVALISVGFVHHSLWLTSVIFILGMGLNGAIYCGFKINHLDLSPRFAGLLISVTNCVANLVGLMAPMVAGHVIDPKPSVENWRIVFYIAAGVFIFTASFYNVFASGKQQW", "length": 479 }, "evidence": [ { "id": "MGI:1924105", "url": "https://alliancegenome.org/gene/MGI:1924105#orthology", "database": "AGR" }, { "id": "HGNC:10933", "url": "https://alliancegenome.org/gene/HGNC:10933#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060929-1158", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-1158#orthology", "database": "AGR" }, { "id": "SGD:S000003492", "url": "https://alliancegenome.org/gene/SGD:S000003492#orthology", "database": "AGR" }, { "id": "SGD:S000003913", "url": "https://alliancegenome.org/gene/SGD:S000003913#orthology", "database": "AGR" }, { "id": "SGD:S000003994", "url": "https://alliancegenome.org/gene/SGD:S000003994#orthology", "database": "AGR" }, { "id": "SGD:S000001428", "url": "https://alliancegenome.org/gene/SGD:S000001428#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VYG7", "url": "https://www.uniprot.org/uniprotkb/Q9VYG7" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VYG7", "url": "https://www.uniprot.org/uniprotkb/Q9VYG7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "Q9VYG7", "url": "https://www.uniprot.org/uniprotkb/Q9VYG7" } ], "pmid": "" }, { "name": "phosphate ion transport", "id": "GO:0006817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006817", "evidence": [ { "database": "UniProtKB", "id": "Q9VYG7", "url": "https://www.uniprot.org/uniprotkb/Q9VYG7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "Q9VYG7", "url": "https://www.uniprot.org/uniprotkb/Q9VYG7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 106, "end_pos": 108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 123, "end_pos": 125, "annotation": "n_glycosylation_sequon" }, { "start_pos": 24, "end_pos": 26, "annotation": "n_glycosylation_sequon" }, { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" }, { "start_pos": 98, "end_pos": 100, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VYG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VYG7" }, { "id": "PS50850", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50850" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Major facilitator superfamily (MFS) profile", "eco_id": "ECO_0000259", "start_pos": 92, "end_pos": 542, "start_aa": "Ala", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 106, "end_pos": 108 }, { "start_pos": 123, "end_pos": 125 }, { "start_pos": 24, "end_pos": 26 }, { "start_pos": 88, "end_pos": 90 }, { "start_pos": 98, "end_pos": 100 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { 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"hyperferritinemia with or without cataract", "description": "" }, { "id": "DOID:0111256", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111256", "name": "hereditary hyperferritinemia with congenital cataracts", "description": "" }, { "id": "MONDO:0010952", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010952", "name": "hereditary hyperferritinemia with congenital cataracts", "description": "Hereditary hyperferritinemia with congenital cataracts is characterized by the association of early onset (although generally absent at birth) cataract with persistently raised plasma ferritin concentrations in the absence of iron overload." }, { "id": "MONDO:0010952", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010952", "name": "HHCS", "description": "" }, { "id": "MONDO:0010952", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010952", "name": "Hyperferritinemia Cataract 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"Hyperferritinemia with or without cataract", "description": "Hyperferritinemia with or without cataract" } ], "unlinked_id_list": [], "evidence": [ { "id": "0111256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111256" } ] }, { "disease_id": "DOID:1289", "recommended_name": { "id": "DOID:1289", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons." }, "synonyms": [ { "id": "DOID:1289", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1289", "name": "degenerative disease", "description": "" } ], "unlinked_id_list": [ "DOID:0112328", "DOID:0050953", "DOID:0111828", "DOID:0050765", "DOID:681", "DOID:0112322" ], "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ] }, { "disease_id": "DOID:1508", "recommended_name": { "id": "DOID:1508", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1508", "name": "candidiasis", "description": "An opportunistic mycosis that involves fungal infection of the mouth, throat, skin, scalp, vagina, fingers, nails, bronchi, lungs, heart and brain by Candida species, of which Candida albicans is the most common. Systemic Candida infections are usually confined to severely immunocompromised persons." }, "synonyms": [ { "id": "DOID:1508", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1508", "name": "Disseminated candidiasis", "description": "" }, { "id": "DOID:1508", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1508", "name": "systemic candidiasis", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "1508", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1508" } ] }, { "disease_id": "DOID:6000", "recommended_name": { "id": "DOID:6000", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:6000", "name": "congestive heart failure", "description": "A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body." }, "synonyms": [ { "id": "DOID:6000", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:6000", "name": "CHF", "description": "" }, { "id": "DOID:6000", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:6000", "name": "Cardiac Failure Congestive", "description": "" }, { "id": "DOID:6000", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:6000", "name": "Congestive heart disease", "description": "" }, { "id": "DOID:6000", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:6000", "name": "Weak heart", "description": "" } ], "unlinked_id_list": [ "DOID:12326" ], "evidence": [ { "id": "6000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6000" } ] }, { "disease_id": "DOID:679", "recommended_name": { "id": "DOID:679", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:679", "name": "basal ganglia disease", "description": "A brain disease that is characterized by dysfunctional movement, located_in basal ganglia that has_material_basis_in diseased components of the basal ganglia and associated neural circuits." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "679", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:679" } ] }, { "disease_id": "DOID:684", "recommended_name": { "id": "DOID:684", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver." }, "synonyms": [ { "id": "DOID:684", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:684", "name": "Hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma", "description": "A malignant tumor that arises from hepatocytes. Hepatocellular carcinoma is relatively rare in the United States but very common in all African countries south of the Sahara and in Southeast Asia. Most cases are seen in patients over the age of 50 years, but this tumor can also occur in younger individuals and even in children. Hepatocellular carcinoma is more common in males than females and is associated with hepatitis B, hepatitis C, chronic alcohol abuse and cirrhosis. Serum elevation of alpha-fetoprotein occurs in a large percentage of patients with hepatocellular carcinoma. Grossly, hepatocellular carcinoma may present as a single mass, as multiple nodules, or as diffuse liver involvement. Microscopically, there is a wide range of differentiation from tumor to tumor (well differentiated to poorly differentiated tumors). Hepatocellular carcinomas quickly metastasize to regional lymph nodes and lung. The overall median survival of untreated liver cell carcinoma is about 4 months. The most effective treatment of hepatocellular carcinoma is complete resection of the tumor. Lately, an increasing number of tumors have been treated with liver transplantation." }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "HCC", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "cancer, hepatocellular", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of liver", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of the liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma, hepatocellular, malignant", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatoblastoma, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular adenocarcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular cancer", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular cancer, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma, childhood type, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver cell cancer (hepatocellular carcinoma)", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver cell carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "primary carcinoma of liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "primary carcinoma of the liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "adult hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "adult primary hepatocellular carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma", "description": "A malignant tumor that arises from hepatocytes. Hepatocellular carcinoma is relatively rare in the United States but very common in all African countries south of the Sahara and in Southeast Asia. Most cases are seen in patients over the age of 50 years, but this tumor can also occur in younger individuals and even in children. Hepatocellular carcinoma is more common in males than females and is associated with hepatitis B, hepatitis C, chronic alcohol abuse and cirrhosis. Serum elevation of alpha-fetoprotein occurs in a large percentage of patients with hepatocellular carcinoma. Grossly, hepatocellular carcinoma may present as a single mass, as multiple nodules, or as diffuse liver involvement. Microscopically, there is a wide range of differentiation from tumor to tumor (well differentiated to poorly differentiated tumors). Hepatocellular carcinomas quickly metastasize to regional lymph nodes and lung. The overall median survival of untreated liver cell carcinoma is about 4 months. The most effective treatment of hepatocellular carcinoma is complete resection of the tumor. Lately, an increasing number of tumors have been treated with liver transplantation." }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "HCC", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "cancer, hepatocellular", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of liver", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of the liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma, hepatocellular, malignant", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatoblastoma, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular adenocarcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular cancer", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular cancer, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma, childhood type, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver cell cancer (hepatocellular carcinoma)", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver cell carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "primary carcinoma of liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "primary carcinoma of the liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "adult hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "adult primary hepatocellular carcinoma", "description": "" }, { "id": "MIM:114550", "resource": "MIM", "url": "https://www.omim.org/entry/114550", "name": "Hepatocellular carcinoma", "description": "Hepatocellular carcinoma" } ], "unlinked_id_list": [], "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VYH1", "url": "https://www.uniprot.org/uniprotkb/Q9VYH1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Fer3HCH", "url": "https://www.uniprot.org/uniprotkb/Q9VYH1", "locus": { "chromosome": "X", "start_pos": 13107382, "end_pos": 13108194, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0030449", "url": "https://www.ensemblgenomes.org/id/FBgn0030449" } ] } } ], "crossref": [ { "id": "FB:FBgn0030449", "url": "https://alliancegenome.org/gene/FB:FBgn0030449", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0030449", "url": "https://bgee.org/?page=gene&gene_id=FBgn0030449", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01056", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01056", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0030449", "url": "https://flybase.org/reports/FBgn0030449", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "32260", "url": "https://www.ncbi.nlm.nih.gov/gene/32260", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001519", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001519", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009040", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009040", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009078", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009078", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG4349", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG4349", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WNSAKDA", "url": "https://omabrowser.org/oma/group/WNSAKDA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VYH1", "url": "https://www.orthodb.org/?gene=Q9VYH1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11431", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11431", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11431:SF75", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11431:SF75", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00210", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00210", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-432722", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-432722", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-917937", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-917937", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_572854", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572854", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "11148", "url": "https://www.rhea-db.org/rhea/11148", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q9VYH1", "url": "https://www.uniprot.org/uniprotkb/Q9VYH1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VYH1-1", "url": "https://www.uniprot.org/uniprotkb/Q9VYH1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAWCFRDIRRHMCMLVRQNFAKSCEKKLNDQINMELKASHQYLAMAYHFDRSDISSPGMHRFFLKASVEEREHAEKIMTYMNKRGGLIILSSVPQPLPCFASTLDALKHAMKMELEVNKHLLDLHALAGKEADPNLCDFIEANFLQEQVDGQKILADYISQLEKAQNQVGEFLFDKYMGSGMHPAK", "length": 186, "header": "tr|Q9VYH1-1|Q9VYH1_DROME Isoform 1 of Ferritin OS=Drosophila melanogaster OX=7227 GN=Fer3HCH PE=3 SV=1 CANONICAL=Q9VYH1-1" }, "isoforms": [ { "isoform_ac": "Q9VYH1-1", "url": "https://www.uniprot.org/uniprotkb/Q9VYH1/entry#Q9VYH1-1", "sequence": { "sequence": "MAWCFRDIRRHMCMLVRQNFAKSCEKKLNDQINMELKASHQYLAMAYHFDRSDISSPGMHRFFLKASVEEREHAEKIMTYMNKRGGLIILSSVPQPLPCFASTLDALKHAMKMELEVNKHLLDLHALAGKEADPNLCDFIEANFLQEQVDGQKILADYISQLEKAQNQVGEFLFDKYMGSGMHPAK", "length": 186, "header": "tr|Q9VYH1-1|Q9VYH1_DROME Isoform 1 of Ferritin OS=Drosophila melanogaster OX=7227 GN=Fer3HCH PE=3 SV=1 CANONICAL=Q9VYH1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VYH1", "url": "https://www.uniprot.org/uniprotkb/Q9VYH1" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VYH1", "url": "https://www.uniprot.org/uniprotkb/Q9VYH1" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VYH1", "url": "https://www.uniprot.org/uniprotkb/Q9VYH1" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VYH1", "url": "https://www.uniprot.org/uniprotkb/Q9VYH1" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VYH1", "url": "https://www.uniprot.org/uniprotkb/Q9VYH1" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VYH1", "url": "https://www.uniprot.org/uniprotkb/Q9VYH1" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VYH1", "url": "https://www.uniprot.org/uniprotkb/Q9VYH1" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VYH1", "url": "https://www.uniprot.org/uniprotkb/Q9VYH1" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VYH1", "url": "https://www.uniprot.org/uniprotkb/Q9VYH1" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VYH1", "url": "https://www.uniprot.org/uniprotkb/Q9VYH1" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VYH1", "url": "https://www.uniprot.org/uniprotkb/Q9VYH1" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG4349", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG4349", "resource": "KEGG Pathway" }, { "id": "R-DME-432722", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-432722", "resource": "Reactome", "description": "Golgi Associated Vesicle Biogenesis" }, { "id": "R-DME-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-DME-917937", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-917937", "resource": "Reactome", "description": "Iron uptake and transport" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K1G6-1", "protein_name": "Ferritin", "gene_name": "Fthl17b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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{ "id": "RGD:1594594", "url": "https://alliancegenome.org/gene/RGD:1594594#orthology", "database": "AGR" }, { "id": "HGNC:3987", "url": "https://alliancegenome.org/gene/HGNC:3987#orthology", "database": "AGR" }, { "id": "HGNC:33525", "url": "https://alliancegenome.org/gene/HGNC:33525#orthology", "database": "AGR" }, { "id": "MGI:3642940", "url": "https://alliancegenome.org/gene/MGI:3642940#orthology", "database": "AGR" }, { "id": "RGD:1560203", "url": "https://alliancegenome.org/gene/RGD:1560203#orthology", "database": "AGR" }, { "id": "RGD:1563378", "url": "https://alliancegenome.org/gene/RGD:1563378#orthology", "database": "AGR" }, { "id": "FB:FBgn0030449", "url": "https://alliancegenome.org/gene/FB:FBgn0030449#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AHC6-1", "protein_name": "Ferritin", "gene_name": "Fthl17c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEAPSRVRQNYDWQCEDAINTHIQLRLYASYVYMSMAVYFDRDDVAQENFKRFFLTKSHNCQTSAEMFMHLQNKRGGCISLQDIARPERDSWHGGFQAMECAFHMEMLINQSLLNMHEVAKEKGDPHLCHFLEQNCLDQQVDILKEMSGYLTNLRQMGAVEHNLAEYLFDKLSLS", "length": 176 }, "evidence": [ { "id": "RGD:1594594", "url": "https://alliancegenome.org/gene/RGD:1594594#orthology", "database": "AGR" }, { "id": "HGNC:3987", "url": "https://alliancegenome.org/gene/HGNC:3987#orthology", "database": "AGR" }, { "id": "HGNC:33525", "url": "https://alliancegenome.org/gene/HGNC:33525#orthology", "database": "AGR" }, { "id": "MGI:3705221", "url": "https://alliancegenome.org/gene/MGI:3705221#orthology", "database": "AGR" }, { "id": "RGD:1560203", "url": "https://alliancegenome.org/gene/RGD:1560203#orthology", "database": "AGR" }, { "id": "RGD:1563378", "url": "https://alliancegenome.org/gene/RGD:1563378#orthology", "database": "AGR" }, { "id": "FB:FBgn0030449", "url": "https://alliancegenome.org/gene/FB:FBgn0030449#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZC26-1", "protein_name": "Ferritin", "gene_name": "Fthl17fl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEASSQVRQNYDRCCEDAINNHIRLLLQASYSYLSMAFYFDRDDVALGNFKRFFLSKSHNCKASAEMFVFMQNKRGGHVFLPSIAKPDRESWHGGLRAMECAFRMEMTINQSLLNMHELAKGKDDAHLCDFLGQHCLDQQVHVLKKMGGYLTNLRQMGAPEQGLAEYLFDKLSLS", "length": 176 }, "evidence": [ { "id": "HGNC:3987", "url": "https://alliancegenome.org/gene/HGNC:3987#orthology", "database": "AGR" }, { "id": "HGNC:33525", "url": "https://alliancegenome.org/gene/HGNC:33525#orthology", "database": "AGR" }, { "id": "MGI:3642940", "url": "https://alliancegenome.org/gene/MGI:3642940#orthology", "database": "AGR" }, { "id": "MGI:1933180", "url": "https://alliancegenome.org/gene/MGI:1933180#orthology", "database": "AGR" }, { "id": "MGI:3705221", "url": "https://alliancegenome.org/gene/MGI:3705221#orthology", "database": "AGR" }, { "id": "RGD:1563378", "url": "https://alliancegenome.org/gene/RGD:1563378#orthology", "database": "AGR" }, { "id": "FB:FBgn0030449", "url": "https://alliancegenome.org/gene/FB:FBgn0030449#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZIZ8-1", "protein_name": "Ferritin", "gene_name": "RGD1560203", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEASSQVRQNYDRCCEEAVNTHIRLLLQASYSYLSMAFYFDRDDVALENFKRFFLSKSHDCKASVEMFVFMQNKRGGHVFLPSIAKPDRKSWQGGFRAMECAFRMEMTINQSLLNLHELAKGKGDAHLCNFLGQHCLDQQVHVLKKIGGYLTNLRQMGAPEQALAEYLFDKLSLS", "length": 176 }, "evidence": [ { "id": "HGNC:3987", "url": "https://alliancegenome.org/gene/HGNC:3987#orthology", "database": "AGR" }, { "id": "HGNC:33525", "url": "https://alliancegenome.org/gene/HGNC:33525#orthology", "database": "AGR" }, { "id": "MGI:3642940", "url": "https://alliancegenome.org/gene/MGI:3642940#orthology", "database": "AGR" }, { "id": "MGI:1933180", "url": 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"id": "MGI:1914884", "url": "https://alliancegenome.org/gene/MGI:1914884#orthology", "database": "AGR" }, { "id": "HGNC:17345", "url": "https://alliancegenome.org/gene/HGNC:17345#orthology", "database": "AGR" }, { "id": "FB:FBgn0030449", "url": "https://alliancegenome.org/gene/FB:FBgn0030449#orthology", "database": "AGR" }, { "id": "Q9VYH1", "url": "https://omabrowser.org/oma/group/Q9VYH1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A879-1", "protein_name": "Ferritin", "gene_name": "4933416E14Rikl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSAWSHQNYTTEVEAMIDRLISMHLEASDRYLSLGFVFKDDCSVAGLVHFFRDLSEEKRQAAYLLLMQTRQSDCGHFSNGPTVPSYQCDGSLDAMETTLALEKNLNQVLLDLHALGSSNADFQLCHFLEKHFLEKEMNLIKKISDYLTNLRQQASEEESLSECLLKRLTLNSD", "length": 173 }, "evidence": [ { "id": "RGD:1561661", "url": "https://alliancegenome.org/gene/RGD:1561661#orthology", "database": "AGR" }, { "id": "FB:FBgn0030449", "url": "https://alliancegenome.org/gene/FB:FBgn0030449#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LTX5-1", "protein_name": "Ferritin", "gene_name": "Fthl17a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAASVSQMEQTYLSESNAALNSQIQLQLYGSYIYLSMASFCNQEEVALGSFALFFLRQSQKWMGRTEMLFSLLTERQGSLTLGRIASQDRQDWLDGLMAMECAFHLEKTLNQSLLQLYNLANSKGDLYLCNFLKSHFLPQQVEILKEMGGYMTNLRRMGAPENRNAEKLFDQLTMADSIKEK", "length": 182 }, "evidence": [ { "id": "RGD:1584678", "url": "https://alliancegenome.org/gene/RGD:1584678#orthology", "database": "AGR" }, { "id": "HGNC:3987", "url": "https://alliancegenome.org/gene/HGNC:3987#orthology", "database": "AGR" }, { "id": "FB:FBgn0030449", "url": "https://alliancegenome.org/gene/FB:FBgn0030449#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MMZ2-1", "protein_name": "Ferritin", "gene_name": "FTMT", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLPCSLFLPKHISTSLVFLRSARHGFALLPRWVPRLSSDYPPAAPIRLLAAAASSRRPADGAGAPSRVRQNFHPDSEAAINRQINLELYASYVYLSMAYYFSRDDVALHNFARYFLRLSREETEHAEKLMRLQNQRGGLICLQDIKKPDQNDWKSGLNAMECALLLEKNVNQSLLELHTLASDKGDPHLCDFLETHYLNEQVKSIKELGDHVNNLVKMGAPESGLAEYLFDKHTLGNENNHN", "length": 242 }, "evidence": [ { "id": "Q9VYH1", "url": "https://omabrowser.org/oma/group/Q9VYH1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P02792-1", "protein_name": "Ferritin light chain", "gene_name": "FTL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSQIRQNYSTDVEAAVNSLVNLYLQASYTYLSLGFYFDRDDVALEGVSHFFRELAEEKREGYERLLKMQNQRGGRALFQDIKKPAEDEWGKTPDAMKAAMALEKKLNQALLDLHALGSARTDPHLCDFLETHFLDEEVKLIKKMGDHLTNLHRLGGPEAGLGEYLFERLTLKHD", "length": 175 }, "evidence": [ { "id": "RGD:2322860", "url": "https://alliancegenome.org/gene/RGD:2322860#orthology", "database": "AGR" }, { "id": "HGNC:3999", "url": "https://alliancegenome.org/gene/HGNC:3999#orthology", "database": "AGR" }, { "id": "MGI:95589", "url": "https://alliancegenome.org/gene/MGI:95589#orthology", "database": "AGR" }, { "id": "RGD:1560687", "url": "https://alliancegenome.org/gene/RGD:1560687#orthology", "database": "AGR" }, { "id": "RGD:1561055", "url": "https://alliancegenome.org/gene/RGD:1561055#orthology", "database": "AGR" }, { "id": "RGD:2324713", "url": "https://alliancegenome.org/gene/RGD:2324713#orthology", "database": "AGR" }, { "id": "RGD:61813", "url": "https://alliancegenome.org/gene/RGD:61813#orthology", "database": "AGR" }, { "id": "RGD:2318303", "url": "https://alliancegenome.org/gene/RGD:2318303#orthology", "database": "AGR" }, { "id": "RGD:1566189", "url": "https://alliancegenome.org/gene/RGD:1566189#orthology", "database": "AGR" }, { "id": "RGD:2325062", "url": "https://alliancegenome.org/gene/RGD:2325062#orthology", "database": "AGR" }, { "id": "FB:FBgn0030449", "url": "https://alliancegenome.org/gene/FB:FBgn0030449#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P02793-1", "protein_name": "Ferritin light chain 1", "gene_name": "Ftl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTSQIRQNYSTEVEAAVNRLVNLHLRASYTYLSLGFFFDRDDVALEGVGHFFRELAEEKREGAERLLKLQNERGGRALFQDVQKPSQDEWGKTLEAMEAALALEKNLNQALLDLHALGSARTDPHLCDFLESHFLDKEVKLIKKMGNHLTNLRRVAGPQPAQTGVAQASLGEYLFERLTLKHD", "length": 183 }, "evidence": [ { "id": "RGD:2322860", "url": "https://alliancegenome.org/gene/RGD:2322860#orthology", "database": "AGR" }, { "id": "HGNC:3999", "url": "https://alliancegenome.org/gene/HGNC:3999#orthology", "database": "AGR" }, { "id": "MGI:95589", "url": "https://alliancegenome.org/gene/MGI:95589#orthology", "database": "AGR" }, { "id": "RGD:1560687", "url": "https://alliancegenome.org/gene/RGD:1560687#orthology", "database": "AGR" }, { "id": "RGD:1561055", "url": "https://alliancegenome.org/gene/RGD:1561055#orthology", "database": "AGR" }, { "id": "RGD:2324713", "url": "https://alliancegenome.org/gene/RGD:2324713#orthology", "database": "AGR" }, { "id": "RGD:61813", "url": "https://alliancegenome.org/gene/RGD:61813#orthology", "database": "AGR" }, { "id": "RGD:2318303", "url": "https://alliancegenome.org/gene/RGD:2318303#orthology", "database": "AGR" }, { "id": "RGD:1566189", "url": "https://alliancegenome.org/gene/RGD:1566189#orthology", "database": "AGR" }, { "id": "RGD:2325062", "url": "https://alliancegenome.org/gene/RGD:2325062#orthology", "database": "AGR" }, { "id": "FB:FBgn0030449", "url": "https://alliancegenome.org/gene/FB:FBgn0030449#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P02794-1", "protein_name": "Ferritin heavy chain", "gene_name": "FTH1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLGDSDNES", "length": 183 }, "evidence": [ { "id": "MGI:95588", "url": "https://alliancegenome.org/gene/MGI:95588#orthology", "database": "AGR" }, { "id": "RGD:1596174", "url": "https://alliancegenome.org/gene/RGD:1596174#orthology", "database": "AGR" }, { "id": "RGD:2635", "url": "https://alliancegenome.org/gene/RGD:2635#orthology", "database": "AGR" }, { "id": "HGNC:3976", "url": "https://alliancegenome.org/gene/HGNC:3976#orthology", "database": "AGR" }, { "id": "FB:FBgn0030449", "url": "https://alliancegenome.org/gene/FB:FBgn0030449#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P09528-1", "protein_name": "Ferritin heavy chain", "gene_name": "Fth1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTTASPSQVRQNYHQDAEAAINRQINLELYASYVYLSMSCYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDRDDWESGLNAMECALHLEKSVNQSLLELHKLATDKNDPHLCDFIETYYLSEQVKSIKELGDHVTNLRKMGAPEAGMAEYLFDKHTLGHGDES", "length": 182 }, "evidence": [ { "id": "MGI:95588", "url": "https://alliancegenome.org/gene/MGI:95588#orthology", "database": "AGR" }, { "id": "RGD:1596174", "url": "https://alliancegenome.org/gene/RGD:1596174#orthology", "database": "AGR" }, { "id": "RGD:2635", "url": "https://alliancegenome.org/gene/RGD:2635#orthology", "database": "AGR" }, { "id": "HGNC:3976", "url": "https://alliancegenome.org/gene/HGNC:3976#orthology", "database": "AGR" }, { "id": "FB:FBgn0030449", "url": "https://alliancegenome.org/gene/FB:FBgn0030449#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0C7X4-1", "protein_name": "Putative ferritin heavy polypeptide-like 19", "gene_name": "FTH1P19", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAFYFDQDDAALEHFDRYFLRQSQEKREHAQELMSLQNLRGGRICLHDIRKPEGQGWESGLKAMECTFHLEKNINQSLLELHQLARENGDPQLCDFLENDFLNQQAKTIKELGGYLSNLHKMGAPEAGLAEYLFNKLTLGRSQKHTRAQTGPTATGCLPLLAPPGGTSMFPFQNILFIFLLSVLPLLAIKLSVLKAIKVSS", "length": 201 }, "evidence": [ { "id": "RGD:1594594", "url": "https://alliancegenome.org/gene/RGD:1594594#orthology", "database": "AGR" }, { "id": "RGD:41038485", "url": "https://alliancegenome.org/gene/RGD:41038485#orthology", "database": "AGR" }, { "id": "RGD:1561106", "url": "https://alliancegenome.org/gene/RGD:1561106#orthology", "database": "AGR" }, { "id": "HGNC:33525", "url": "https://alliancegenome.org/gene/HGNC:33525#orthology", "database": "AGR" }, { "id": "MGI:3642940", "url": "https://alliancegenome.org/gene/MGI:3642940#orthology", "database": "AGR" }, { "id": "MGI:1933180", "url": "https://alliancegenome.org/gene/MGI:1933180#orthology", "database": "AGR" }, { "id": "MGI:3705221", "url": "https://alliancegenome.org/gene/MGI:3705221#orthology", "database": "AGR" }, { "id": "RGD:1560203", "url": "https://alliancegenome.org/gene/RGD:1560203#orthology", "database": "AGR" }, { "id": "RGD:1563378", "url": "https://alliancegenome.org/gene/RGD:1563378#orthology", "database": "AGR" }, { "id": "FB:FBgn0030449", "url": "https://alliancegenome.org/gene/FB:FBgn0030449#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P19132-1", "protein_name": "Ferritin heavy chain", "gene_name": "Fth1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTTASPSQVRQNYHQDSEAAINRQINLELYASYVYLSMSCYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDRDDWESGLNAMRCALHLEKSVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKSIKELGDHVTNLRKMGAPESGMAEYLFDKHTLGHGDES", "length": 182 }, "evidence": [ { "id": "MGI:95588", "url": "https://alliancegenome.org/gene/MGI:95588#orthology", "database": "AGR" }, { "id": "RGD:2635", "url": "https://alliancegenome.org/gene/RGD:2635#orthology", "database": "AGR" }, { "id": "HGNC:3976", "url": "https://alliancegenome.org/gene/HGNC:3976#orthology", "database": "AGR" }, { "id": "FB:FBgn0030449", "url": "https://alliancegenome.org/gene/FB:FBgn0030449#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P29391-1", "protein_name": "Ferritin light chain 1", "gene_name": "Ftl1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSQIRQNYSTEVEAAVNRLVNLHLRASYTYLSLGFFFDRDDVALEGVGHFFRELAEEKREGAERLLEFQNDRGGRALFQDVQKPSQDEWGKTQEAMEAALAMEKNLNQALLDLHALGSARTDPHLCDFLESHYLDKEVKLIKKMGNHLTNLRRVAGPQPAQTGAPQGSLGEYLFERLTLKHD", "length": 183 }, "evidence": [ { "id": "HGNC:3999", "url": "https://alliancegenome.org/gene/HGNC:3999#orthology", "database": "AGR" }, { "id": "MGI:95589", "url": "https://alliancegenome.org/gene/MGI:95589#orthology", "database": "AGR" }, { "id": "RGD:61813", "url": "https://alliancegenome.org/gene/RGD:61813#orthology", "database": "AGR" }, { "id": "FB:FBgn0030449", "url": "https://alliancegenome.org/gene/FB:FBgn0030449#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7KRU8-1", "protein_name": "Ferritin heavy chain", "gene_name": "Fer1HCH", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVKLIASLLLLAVVAQAYGDFKCSLAVPEITKDWVDMKDACIKGMRNQIQEEINASYQYLAMGAYFSRDTVNRPGFAEHFFKAAKEEREHGSKLVEYLSMRGQLTEGVSDLINVPTVAKQEWTDGAAALSDALDLEIKVTKSIRKLIQTCENKPYNHYHLVDYLTGVYLEEQLHGQRELAGKLTTLKKMMDTNGELGEFLFDKTL", "length": 205 }, "evidence": [ { "id": "RGD:1306563", "url": "https://alliancegenome.org/gene/RGD:1306563#orthology", "database": "AGR" }, { "id": "MGI:1914884", "url": "https://alliancegenome.org/gene/MGI:1914884#orthology", "database": "AGR" }, { "id": "MGI:95588", "url": "https://alliancegenome.org/gene/MGI:95588#orthology", "database": "AGR" }, { "id": "RGD:1594594", "url": "https://alliancegenome.org/gene/RGD:1594594#orthology", "database": "AGR" }, { "id": "RGD:41038485", "url": "https://alliancegenome.org/gene/RGD:41038485#orthology", "database": "AGR" }, { "id": "RGD:1596174", "url": "https://alliancegenome.org/gene/RGD:1596174#orthology", "database": "AGR" }, { "id": "RGD:1584678", "url": "https://alliancegenome.org/gene/RGD:1584678#orthology", "database": "AGR" }, { "id": "RGD:2635", "url": "https://alliancegenome.org/gene/RGD:2635#orthology", "database": "AGR" }, { "id": "RGD:1561106", "url": "https://alliancegenome.org/gene/RGD:1561106#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8N4E7-1", "protein_name": "Ferritin, mitochondrial", "gene_name": "FTMT", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLSCFRLLSRHISPSLASLRPVRCCFALPLRWAPGRPLDPRQIAPRRPLAAAASSRDPTGPAAGPSRVRQNFHPDSEAAINRQINLELYASYVYLSMAYYFSRDDVALNNFSRYFLHQSREETEHAEKLMRLQNQRGGRIRLQDIKKPEQDDWESGLHAMECALLLEKNVNQSLLELHALASDKGDPHLCDFLETYYLNEQVKSIKELGDHVHNLVKMGAPDAGLAEYLFDTHTLGNENKQN", "length": 242 }, "evidence": [ { "id": "RGD:1306563", "url": "https://alliancegenome.org/gene/RGD:1306563#orthology", "database": "AGR" }, { "id": "MGI:1914884", "url": "https://alliancegenome.org/gene/MGI:1914884#orthology", "database": "AGR" }, { "id": "HGNC:17345", "url": "https://alliancegenome.org/gene/HGNC:17345#orthology", "database": "AGR" }, { "id": "FB:FBgn0030449", "url": "https://alliancegenome.org/gene/FB:FBgn0030449#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99MX2-1", "protein_name": "Ferritin heavy polypeptide-like 17E", "gene_name": "Fthl17e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEAPSRMQQNYDWQCEDAINTHIQLCLYASYEYMSMAVYFDRDDVAQENFKRFFLTKSHNCQTSAEMFMHLQNKRGGCSSLQGIARPERDSWHGGFQAMECAFHMEMLINQSLLNMHEVAKEKGDPHLCHFLEQNCLDQQVDILKEMSGYLTNLRQMGAVEHNLAEYLFDKLSLS", "length": 176 }, "evidence": [ { "id": "RGD:1594594", "url": "https://alliancegenome.org/gene/RGD:1594594#orthology", "database": "AGR" }, { "id": "HGNC:3987", "url": "https://alliancegenome.org/gene/HGNC:3987#orthology", "database": "AGR" }, { "id": "HGNC:33525", "url": "https://alliancegenome.org/gene/HGNC:33525#orthology", "database": "AGR" }, { "id": "MGI:1933180", "url": "https://alliancegenome.org/gene/MGI:1933180#orthology", "database": "AGR" }, { "id": "RGD:1560203", "url": "https://alliancegenome.org/gene/RGD:1560203#orthology", "database": "AGR" }, { "id": "RGD:1563378", "url": "https://alliancegenome.org/gene/RGD:1563378#orthology", "database": "AGR" }, { "id": "FB:FBgn0030449", "url": "https://alliancegenome.org/gene/FB:FBgn0030449#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BXU8-1", "protein_name": "Ferritin heavy polypeptide-like 17", "gene_name": "FTHL17", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATAQPSQVRQKYDTNCDAAINSHITLELYTSYLYLSMAFYFNRDDVALENFFRYFLRLSDDKMEHAQKLMRLQNLRGGHICLHDIRKPECQGWESGLVAMESAFHLEKNVNQSLLDLYQLAVEKGDPQLCHFLESHYLHEQVKTIKELGGYVSNLRKICSPEAGLAEYLFDKLTLGGRVKET", "length": 183 }, "evidence": [ { "id": "RGD:41038485", "url": "https://alliancegenome.org/gene/RGD:41038485#orthology", "database": "AGR" }, { "id": "RGD:1584678", "url": "https://alliancegenome.org/gene/RGD:1584678#orthology", "database": "AGR" }, { "id": "RGD:1561106", "url": "https://alliancegenome.org/gene/RGD:1561106#orthology", "database": "AGR" }, { "id": "HGNC:3987", "url": "https://alliancegenome.org/gene/HGNC:3987#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1948", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1948#orthology", "database": "AGR" }, { "id": "MGI:3642940", "url": "https://alliancegenome.org/gene/MGI:3642940#orthology", "database": "AGR" }, { "id": "MGI:1933180", "url": "https://alliancegenome.org/gene/MGI:1933180#orthology", "database": "AGR" }, { "id": "MGI:3705221", "url": "https://alliancegenome.org/gene/MGI:3705221#orthology", "database": "AGR" }, { "id": "RGD:1560203", "url": "https://alliancegenome.org/gene/RGD:1560203#orthology", "database": "AGR" }, { "id": "RGD:1563378", "url": "https://alliancegenome.org/gene/RGD:1563378#orthology", "database": "AGR" }, { "id": "FB:FBgn0030449", "url": "https://alliancegenome.org/gene/FB:FBgn0030449#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D5H4-1", "protein_name": "Ferritin, mitochondrial", "gene_name": "Ftmt", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSCFWFFSKHISSALMSLPRVLHRFTAPQCLASRYPLGPLLASPRRLLASVASSQDSTRPSRVRQNFHPDSEAAINRQINLELYASYVYLSMAYYFSRDDVALYNFSKYFLRQSLEEREHAEKLMKLQNQRGGRICLQDIKKPDKDDWECGLRAMECALLLEKNVNQSLLDLHTLASEKGDPHLCDFLETHYLHEQVKSIKELGDHVHNLVTMGAPAAGLAEYLFDKHTLGSESKH", "length": 237 }, "evidence": [ { "id": "RGD:1306563", "url": "https://alliancegenome.org/gene/RGD:1306563#orthology", "database": "AGR" }, { "id": "MGI:1914884", "url": "https://alliancegenome.org/gene/MGI:1914884#orthology", "database": "AGR" }, { "id": "HGNC:17345", "url": "https://alliancegenome.org/gene/HGNC:17345#orthology", "database": "AGR" }, { "id": "FB:FBgn0030449", "url": "https://alliancegenome.org/gene/FB:FBgn0030449#orthology", "database": "AGR" }, { "id": "Q9VYH1", "url": "https://omabrowser.org/oma/group/Q9VYH1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9S756-1", "protein_name": "Ferritin-4, chloroplastic", "gene_name": "FER4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MLLKTVSSSSSSALSLVNFHGVKKDVSPLLPSISSNLRVSSGKSGNLTFSFRASKSSTTDALSGVVFEPFKEVKKELDLVPTSSHLSLARQKYSDECEAAINEQINVEYNVSYVYHAMYAYFDRDNIALKGLAKFFKESSLEEREHAEKLMEYQNKRGGRVKLQSIVMPLSEFEHVDKGDALYGMELALSLEKLVNEKLLNLHSVASKNNDVHLADFIESEFLTEQVEAIKLISEYVAQLRRVGKGHGTWHFNQMLLEG", "length": 259 }, "evidence": [ { "id": "Q9VYH1", "url": "https://omabrowser.org/oma/group/Q9VYH1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VYH1", "url": "https://www.uniprot.org/uniprotkb/Q9VYH1" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "Q9VYH1", "url": "https://www.uniprot.org/uniprotkb/Q9VYH1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular iron ion homeostasis", "id": "GO:0006879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006879", "evidence": [ { "database": "UniProtKB", "id": "Q9VYH1", "url": "https://www.uniprot.org/uniprotkb/Q9VYH1" } ], "pmid": "" }, { "name": "iron ion transport", "id": "GO:0006826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006826", "evidence": [ { "database": "UniProtKB", "id": "Q9VYH1", "url": "https://www.uniprot.org/uniprotkb/Q9VYH1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ferrous iron binding", "id": "GO:0008198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008198", "evidence": [ { "database": "UniProtKB", "id": "Q9VYH1", "url": "https://www.uniprot.org/uniprotkb/Q9VYH1" } ], "pmid": "" }, { "name": "ferroxidase activity", "id": "GO:0004322", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004322", "evidence": [ { "database": "UniProtKB", "id": "Q9VYH1", "url": "https://www.uniprot.org/uniprotkb/Q9VYH1" } ], "pmid": "" }, { "name": "ferric iron binding", "id": "GO:0008199", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008199", "evidence": [ { "database": "UniProtKB", "id": "Q9VYH1", "url": "https://www.uniprot.org/uniprotkb/Q9VYH1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "11148", "name": "", "equation": "4 Fe(2+) + O2 + 4 H(+) = 4 Fe(3+) + 2 H2O", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9W385-1", "Q9VYH1-1", "Q7KRU8-1" ], "evidence": [ { "id": "11148", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/11148" } ] }, { "id": "R-DME-1562626", "name": "Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [ "R-ALL-5691103" ], "enzyme_list": [ "Q7KRU8-1", "Q9VYH1-1" ], "evidence": [ { "id": "R-DME-1562626", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1562626" } ] }, { "id": "R-DME-434362", "name": "Recruitment Of Cytoplasmic Proteins To Vesicles", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q7KRU8-1", "Q9VYH1-1" ], "evidence": [ { "id": "R-DME-434362", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-434362" } ] }, { "id": "R-DME-5691107", "name": "FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [], "output_participant_list": [ "R-ALL-5691135" ], "enzyme_list": [ "Q7KRU8-1", "Q9VYH1-1" ], "evidence": [ { "id": "R-DME-5691107", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-5691107" } ] }, { "id": "R-DME-6798745", "name": "Exocytosis of tertiary granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, tertiary granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q8INK6-1", "A1Z9D5-1", "A1ZBX6-1", "C0HK98-1", "C0HK99-1", "P29349-4", "Q9VV96-1", "Q9W5U2-1", "M9NDS9-1", "Q9W2M5-1", "P29615-1", "Q9V4X2-1", "Q9VYX7-1", "Q8MLW8-1", "Q9W2M7-1", "A1ZBX7-1", "Q9VBF5-1", "Q9VLR2-1", "Q9W122-1", "Q9W4C2-1", "Q7KRU8-1", "P07764-1", "Q8MPP3-1", "Q9W092-1", "B7Z0E0-1", "Q86PD7-1", "Q9W3V1-1", "A1ZAB8-1", "Q8IQM9-1", "Q9VJ39-1", "P37159-1", "P37160-1", "P37161-1", "P83972-1", "Q08694-1", "Q70PY2-1", "Q9VSA5-1", "Q9VUY9-1", "Q9VFR3-1", "Q9VGN8-1", "Q9VHE4-1", "Q9VYH1-1", "Q9VZV2-1", "Q9W2M6-1" ], "evidence": [ { "id": "R-DME-6798745", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6798745" } ] }, { "id": "R-DME-6798751", "name": "Exocytosis of azurophil granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, azurophil granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P40417-3", "A1Z8C9-1", "A1Z9D5-1", "A1ZBX6-1", "Q9VZZ4-1", "P29615-1", "Q7KN62-1", "Q9V9J3-1", "Q9VSC3-1", "A1ZBG9-1", "A1ZBX7-1", "O76895-1", "Q9V420-1", "Q9VMJ5-1", "Q9W4C2-1", "Q7KRU8-1", "P83099-1", "Q8MR45-1", "Q9VTJ4-1", "Q8IPB7-1", "X2JGK6-1", "Q9VVK4-1", "A1ZAB8-1", "Q8IQM9-1", "P37159-1", "P37160-1", "P37161-1", "P83972-1", "Q07152-1", "Q08694-1", "Q9VQX4-1", "Q9VSA5-1", "Q9XTL9-1", "Q9VGE7-1", "Q9VYH1-1" ], "evidence": [ { "id": "R-DME-6798751", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6798751" } ] }, { "id": "R-DME-6800434", "name": "Exocytosis of ficolin-rich granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, ficolin-1-rich granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P40417-3", "Q9V3V6-1", "Q9W1K6-1", "P13060-1", "Q11002-1", "Q9V3H2-1", "Q9VT65-1", "A0A0B4LFW5-1", "X2JF73-1", "P08879-1", "P52034-1", "Q7KN62-1", "Q9V3G3-1", "M9PE19-1", "Q9VFG4-1", "A1ZBG9-1", "Q9VBF5-1", "Q9VLR2-1", "Q9VMJ5-1", "Q9VY87-1", "Q9W122-1", "Q7KRU8-1", "Q9VQH0-1", "P07764-1", "P17336-1", "P52029-1", "Q23976-1", "Q8MPP3-1", "Q9NFT7-1", "Q9VHP0-1", "Q9VP22-1", "A1Z7P1-1", "B7Z0E0-1", "Q9W2H8-1", "X2JEY5-1", "Q9VAN7-1", "Q9VD23-1", "Q86PD7-1", "Q9V3Q4-1", "Q9VTV9-1", "Q9VJ39-1", "O61443-1", "O62619-1", "Q07152-1", "Q95RX5-1", "Q9VUY9-1", "Q9VGE7-1", "Q9VGN8-1", "Q9VYH1-1", "Q9W330-1" ], "evidence": [ { "id": "R-DME-6800434", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6800434" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-5691103", "participant_name": "Fe(3+)O(OH) [cytosol]", "crossref": [ { "id": "78619", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-5691135", "participant_name": "Fe(3+)O(OH) [mitochondrial matrix]", "crossref": [ { "id": "78619", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A0B4LFW5", "gene_name": "Gyg", "activity": [ { "ec_number": "2.4.1.186", "activity": "[1,4-alpha-D-glucosyl](n)-L-tyrosyl-[glycogenin] + UDP-alpha-D-glucose = [1,4-alpha-D-glucosyl](n+1)-L-tyrosyl-[glycogenin] + UDP + H(+).", "evidence": [ { "id": "A0A0B4LFW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LFW5" } ] }, { "ec_number": "2.4.1.186", "activity": "", "evidence": [ { "id": "A0A0B4LFW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LFW5" } ] } ] }, { "uniprot_ac": "A1Z7P1", "gene_name": "Pgm2a", "activity": [ { "ec_number": "5.4.2.7", "activity": "2-deoxy-alpha-D-ribose 1-phosphate = 2-deoxy-D-ribose 5-phosphate.", "evidence": [ { "id": "A1Z7P1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1Z7P1" } ] }, { "ec_number": "5.4.2.-", "activity": "", "evidence": [ { "id": "A1Z7P1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1Z7P1" } ] } ] }, { "uniprot_ac": "A1Z8C9", "gene_name": "anon-AE003828.1", "activity": [ { "ec_number": "3.5.2.17", "activity": "5-hydroxyisourate + H2O = 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H(+).", "evidence": [ { "id": "A1Z8C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1Z8C9" } ] }, { "ec_number": "3.5.2.17", "activity": "", "evidence": [ { "id": "A1Z8C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1Z8C9" } ] } ] }, { "uniprot_ac": "A1Z9D5", "gene_name": "Dmel\\CG30062", "activity": [ { "ec_number": "3.2.1.17", "activity": "Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.", "evidence": [ { "id": "A1Z9D5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1Z9D5" } ] }, { "ec_number": "3.2.1.17", "activity": "", "evidence": [ { "id": "A1Z9D5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1Z9D5" } ] } ] }, { "uniprot_ac": "A1ZAB8", "gene_name": "Dmel\\CG7798", "activity": [ { "ec_number": "3.2.1.17", "activity": "Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.", "evidence": [ { "id": "A1ZAB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1ZAB8" } ] }, { "ec_number": "3.2.1.17", "activity": "", "evidence": [ { "id": "A1ZAB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1ZAB8" } ] } ] }, { "uniprot_ac": "A1ZBG9", "gene_name": "Dmel\\CG15117", "activity": [ { "ec_number": "3.2.1.31", "activity": "a beta-D-glucuronoside + H2O = D-glucuronate + an alcohol.", "evidence": [ { "id": "A1ZBG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1ZBG9" } ] }, { "ec_number": "3.2.1.31", "activity": "", "evidence": [ { "id": "A1ZBG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1ZBG9" } ] } ] }, { "uniprot_ac": "A1ZBX6", "gene_name": "Dmel\\CG16799", "activity": [ { "ec_number": "3.2.1.17", "activity": "Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.", "evidence": [ { "id": "A1ZBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1ZBX6" } ] }, { "ec_number": "3.2.1.17", "activity": "", "evidence": [ { "id": "A1ZBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1ZBX6" } ] } ] }, { "uniprot_ac": "A1ZBX7", "gene_name": "Dmel\\CG11159", "activity": [ { "ec_number": "3.2.1.17", "activity": "Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.", "evidence": [ { "id": "A1ZBX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1ZBX7" } ] }, { "ec_number": "3.2.1.17", "activity": "", "evidence": [ { "id": "A1ZBX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1ZBX7" } ] } ] }, { "uniprot_ac": "B7Z0E0", "gene_name": "Idh", "activity": [ { "ec_number": "1.1.1.42", "activity": "D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH.", "evidence": [ { "id": "B7Z0E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B7Z0E0" } ] }, { "ec_number": "1.1.1.42", "activity": "", "evidence": [ { "id": "B7Z0E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B7Z0E0" } ] } ] }, { "uniprot_ac": "C0HK98", "gene_name": "PGRP-SC1a", "activity": [ { "ec_number": "3.5.1.28", "activity": "Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides.", "evidence": [ { "id": "C0HK98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/C0HK98" } ] }, { "ec_number": "3.5.1.28", "activity": "", "evidence": [ { "id": "C0HK98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/C0HK98" } ] } ] }, { "uniprot_ac": "C0HK99", "gene_name": "PGRP-SC1b", "activity": [ { "ec_number": "3.5.1.28", "activity": "Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides.", "evidence": [ { "id": "C0HK99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/C0HK99" } ] }, { "ec_number": "3.5.1.28", "activity": "", "evidence": [ { "id": "C0HK99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/C0HK99" } ] } ] }, { "uniprot_ac": "M9NDS9", "gene_name": "Cht6", "activity": [ { "ec_number": "3.2.1.14", "activity": "Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins.", "evidence": [ { "id": "M9NDS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9NDS9" } ] }, { "ec_number": "3.2.1.14", "activity": "", "evidence": [ { "id": "M9NDS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9NDS9" } ] } ] }, { "uniprot_ac": "M9PE19", "gene_name": "CG16760", "activity": [ { "ec_number": "2.4.2.1", "activity": "adenosine + phosphate = alpha-D-ribose 1-phosphate + adenine.", "evidence": [ { "id": "M9PE19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9PE19" } ] }, { "ec_number": "2.4.2.1", "activity": "", "evidence": [ { "id": "M9PE19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9PE19" } ] } ] }, { "uniprot_ac": "O61443", "gene_name": "p38b", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "O61443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O61443" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "O61443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O61443" } ] } ] }, { "uniprot_ac": "O62619", "gene_name": "Pyk", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "O62619", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O62619" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "O62619", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O62619" } ] } ] }, { "uniprot_ac": "O76895", "gene_name": "Arg", "activity": [ { "ec_number": "3.5.3.1", "activity": "L-arginine + H2O = urea + L-ornithine.", "evidence": [ { "id": "O76895", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O76895" } ] }, { "ec_number": "3.5.3.1", "activity": "", "evidence": [ { "id": "O76895", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O76895" } ] } ] }, { "uniprot_ac": "P07764", "gene_name": "Aldo", "activity": [ { "ec_number": "4.1.2.13", "activity": "beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate.", "evidence": [ { "id": "P07764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P07764" } ] }, { "ec_number": "4.1.2.13", "activity": "", "evidence": [ { "id": "P07764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P07764" } ] } ] }, { "uniprot_ac": "P08879", "gene_name": "awd", "activity": [ { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P08879", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08879" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P08879", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P08879" } ] } ] }, { "uniprot_ac": "P13060", "gene_name": "eEF2", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "P13060", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13060" } ] } ] }, { "uniprot_ac": "P17336", "gene_name": "Cat", "activity": [ { "ec_number": "1.11.1.6", "activity": "2 H2O2 = O2 + 2 H2O.", "evidence": [ { "id": "P17336", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P17336" } ] }, { "ec_number": "1.11.1.6", "activity": "", "evidence": [ { "id": "P17336", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P17336" } ] } ] }, { "uniprot_ac": "P29349", "gene_name": "csw", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P29349", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P29349" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P29349", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P29349" } ] } ] }, { "uniprot_ac": "P29615", "gene_name": "LysP", "activity": [ { "ec_number": "3.2.1.17", "activity": "Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.", "evidence": [ { "id": "P29615", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P29615" } ] }, { "ec_number": "3.2.1.17", "activity": "", "evidence": [ { "id": "P29615", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P29615" } ] } ] }, { "uniprot_ac": "P37159", "gene_name": "LysE", "activity": [ { "ec_number": "3.2.1.17", "activity": "Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.", "evidence": [ { "id": "P37159", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P37159" } ] }, { "ec_number": "3.2.1.17", "activity": "", "evidence": [ { "id": "P37159", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P37159" } ] } ] }, { "uniprot_ac": "P37160", "gene_name": "LysS", "activity": [ { "ec_number": "3.2.1.17", "activity": "Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.", "evidence": [ { "id": "P37160", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P37160" } ] }, { "ec_number": "3.2.1.17", "activity": "", "evidence": [ { "id": "P37160", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P37160" } ] } ] }, { "uniprot_ac": "P37161", "gene_name": "LysX", "activity": [ { "ec_number": "3.2.1.17", "activity": "Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.", "evidence": [ { "id": "P37161", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P37161" } ] }, { "ec_number": "3.2.1.17", "activity": "", "evidence": [ { "id": "P37161", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P37161" } ] } ] }, { "uniprot_ac": "P40417", "gene_name": "rl", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P40417", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P40417" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P40417", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P40417" } ] } ] }, { "uniprot_ac": "P52029", "gene_name": "Pgi", "activity": [ { "ec_number": "5.3.1.9", "activity": "alpha-D-fructose 6-phosphate = beta-D-fructose 6-phosphate.", "evidence": [ { "id": "P52029", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52029" } ] }, { "ec_number": "5.3.1.9", "activity": "", "evidence": [ { "id": "P52029", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52029" } ] } ] }, { "uniprot_ac": "P52034", "gene_name": "Pfk", "activity": [ { "ec_number": "2.7.1.11", "activity": "beta-D-fructose 6-phosphate + ATP = beta-D-fructose 1,6-bisphosphate + ADP + H(+).", "evidence": [ { "id": "P52034", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52034" } ] }, { "ec_number": "2.7.1.11", "activity": "", "evidence": [ { "id": "P52034", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52034" } ] } ] }, { "uniprot_ac": "P83099", "gene_name": "Pkcdelta", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P83099", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P83099" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "P83099", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P83099" } ] } ] }, { "uniprot_ac": "P83972", "gene_name": "LysD", "activity": [ { "ec_number": "3.2.1.17", "activity": "Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.", "evidence": [ { "id": "P83972", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P83972" } ] }, { "ec_number": "3.2.1.17", "activity": "", "evidence": [ { "id": "P83972", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P83972" } ] } ] }, { "uniprot_ac": "Q07152", "gene_name": "ras", "activity": [ { "ec_number": "1.1.1.205", "activity": "IMP + NAD(+) + H2O = XMP + NADH + H(+).", "evidence": [ { "id": "Q07152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07152" } ] }, { "ec_number": "1.1.1.205", "activity": "", "evidence": [ { "id": "Q07152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q07152" } ] } ] }, { "uniprot_ac": "Q08694", "gene_name": "LysB", "activity": [ { "ec_number": "3.2.1.17", "activity": "Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.", "evidence": [ { "id": "Q08694", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08694" } ] }, { "ec_number": "3.2.1.17", "activity": "", "evidence": [ { "id": "Q08694", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08694" } ] } ] }, { "uniprot_ac": "Q11002", "gene_name": "CalpA", "activity": [ { "ec_number": "3.4.22.-", "activity": "", "evidence": [ { "id": "Q11002", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q11002" } ] } ] }, { "uniprot_ac": "Q23976", "gene_name": "Irbp", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q23976", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q23976" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "Q23976", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q23976" } ] } ] }, { "uniprot_ac": "Q70PY2", "gene_name": "PGRP-SB1", "activity": [ { "ec_number": "3.5.1.28", "activity": "Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides.", "evidence": [ { "id": "Q70PY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q70PY2" } ] }, { "ec_number": "3.5.1.28", "activity": "", "evidence": [ { "id": "Q70PY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q70PY2" } ] } ] }, { "uniprot_ac": "Q7KN62", "gene_name": "TER94", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q7KN62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7KN62" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "Q7KN62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7KN62" } ] } ] }, { "uniprot_ac": "Q7KRU8", "gene_name": "Fer1HCH", "activity": [ { "ec_number": "1.16.3.1", "activity": "4 Fe(2+) + O2 + 4 H(+) = 4 Fe(3+) + 2 H2O.", "evidence": [ { "id": "Q7KRU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7KRU8" } ] }, { "ec_number": "1.16.3.1", "activity": "", "evidence": [ { "id": "Q7KRU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7KRU8" } ] } ] }, { "uniprot_ac": "Q86PD7", "gene_name": "isoQC", "activity": [ { "ec_number": "2.3.2.5", "activity": "N-terminal L-glutaminyl-[peptide] = N-terminal 5-oxo-L-prolyl-[peptide] + NH4(+).", "evidence": [ { "id": "Q86PD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q86PD7" } ] }, { "ec_number": "2.3.2.5", "activity": "", "evidence": [ { "id": "Q86PD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q86PD7" } ] } ] }, { "uniprot_ac": "Q8INK6", "gene_name": "PGRP-LB", "activity": [ { "ec_number": "3.5.1.28", "activity": "Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides.", "evidence": [ { "id": "Q8INK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8INK6" } ] }, { "ec_number": "3.5.1.28", "activity": "", "evidence": [ { "id": "Q8INK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8INK6" } ] } ] }, { "uniprot_ac": "Q8IPB7", "gene_name": "LManII", "activity": [ { "ec_number": "3.2.1.-", "activity": "", "evidence": [ { "id": "Q8IPB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8IPB7" } ] } ] }, { "uniprot_ac": "Q8IQM9", "gene_name": "l(3)72Dp", "activity": [ { "ec_number": "3.4.19.9", "activity": "(6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) + (n-1) H2O = (6S)-5,6,7,8-tetrahydrofolate + (n-1) L-glutamate.", "evidence": [ { "id": "Q8IQM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8IQM9" } ] }, { "ec_number": "3.4.19.9", "activity": "", "evidence": [ { "id": "Q8IQM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8IQM9" } ] } ] }, { "uniprot_ac": "Q8MLW8", "gene_name": "Cht12", "activity": [ { "ec_number": "3.2.1.14", "activity": "Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins.", "evidence": [ { "id": "Q8MLW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8MLW8" } ] } ] }, { "uniprot_ac": "Q8MPP3", "gene_name": "Mmp2", "activity": [ { "ec_number": "3.4.24.-", "activity": "", "evidence": [ { "id": "Q8MPP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8MPP3" } ] } ] }, { "uniprot_ac": "Q8MR45", "gene_name": "", "activity": [ { "ec_number": "3.5.1.26", "activity": "N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine + H2O = N-acetyl-beta-D-glucosaminylamine + L-aspartate + H(+).", "evidence": [ { "id": "Q8MR45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8MR45" } ] }, { "ec_number": "3.5.1.26", "activity": "", "evidence": [ { "id": "Q8MR45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8MR45" } ] } ] }, { "uniprot_ac": "Q95RX5", "gene_name": "Kcmf1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q95RX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95RX5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q95RX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q95RX5" } ] } ] }, { "uniprot_ac": "Q9NFT7", "gene_name": "Hex-T", "activity": [ { "ec_number": "2.7.1.1", "activity": "D-fructose + ATP = D-fructose 6-phosphate + ADP + H(+).", "evidence": [ { "id": "Q9NFT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9NFT7" } ] }, { "ec_number": "2.7.1.1", "activity": "", "evidence": [ { "id": "Q9NFT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9NFT7" } ] } ] }, { "uniprot_ac": "Q9V3G3", "gene_name": "cyp33", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "Q9V3G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9V3G3" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "Q9V3G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9V3G3" } ] } ] }, { "uniprot_ac": "Q9V3H2", "gene_name": "Rpn11", "activity": [ { "ec_number": "3.4.19.-", "activity": "", "evidence": [ { "id": "Q9V3H2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9V3H2" } ] } ] }, { "uniprot_ac": "Q9V3Q4", "gene_name": "Prx4", "activity": [ { "ec_number": "1.11.1.24", "activity": "a hydroperoxide + [thioredoxin]-dithiol = an alcohol + [thioredoxin]-disulfide + H2O.", "evidence": [ { "id": "Q9V3Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9V3Q4" } ] }, { "ec_number": "1.11.1.24", "activity": "", "evidence": [ { "id": "Q9V3Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9V3Q4" } ] } ] }, { "uniprot_ac": "Q9V3V6", "gene_name": "Rpt5", "activity": [ { "ec_number": "5.6.1.5", "activity": "ATP + H2O + polypeptide = ADP + phosphate + unfolded polypeptide.", "evidence": [ { "id": "Q9V3V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9V3V6" } ] } ] }, { "uniprot_ac": "Q9V420", "gene_name": "mPges2", "activity": [ { "ec_number": "5.3.99.3", "activity": "prostaglandin H2 = prostaglandin E2.", "evidence": [ { "id": "Q9V420", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9V420" } ] } ] }, { "uniprot_ac": "Q9V4X2", "gene_name": "PGRP-SC2", "activity": [ { "ec_number": "3.5.1.28", "activity": "Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides.", "evidence": [ { "id": "Q9V4X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9V4X2" } ] }, { "ec_number": "3.5.1.28", "activity": "", "evidence": [ { "id": "Q9V4X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9V4X2" } ] } ] }, { "uniprot_ac": "Q9V9J3", "gene_name": "Src42A", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9V9J3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9V9J3" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q9V9J3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9V9J3" } ] } ] }, { "uniprot_ac": "Q9VAN7", "gene_name": "Pgam1", "activity": [ { "ec_number": "5.4.2.11", "activity": "(2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate.", "evidence": [ { "id": "Q9VAN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VAN7" } ] }, { "ec_number": "5.4.2.4", "activity": "(2R)-3-phospho-glyceroyl phosphate = (2R)-2,3-bisphosphoglycerate + H(+).", "evidence": [ { "id": "Q9VAN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VAN7" } ] }, { "ec_number": "5.4.2.4", "activity": "", "evidence": [ { "id": "Q9VAN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VAN7" } ] }, { "ec_number": "5.4.2.11", "activity": "", "evidence": [ { "id": "Q9VAN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VAN7" } ] } ] }, { "uniprot_ac": "Q9VBF5", "gene_name": "Aldol", "activity": [ { "ec_number": "4.1.2.13", "activity": "beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate.", "evidence": [ { "id": "Q9VBF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VBF5" } ] }, { "ec_number": "4.1.2.13", "activity": "", "evidence": [ { "id": "Q9VBF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VBF5" } ] } ] }, { "uniprot_ac": "Q9VD23", "gene_name": "Pykl1", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "Q9VD23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VD23" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "Q9VD23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VD23" } ] } ] }, { "uniprot_ac": "Q9VFG4", "gene_name": "Pykl3", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "Q9VFG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VFG4" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "Q9VFG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VFG4" } ] } ] }, { "uniprot_ac": "Q9VFR3", "gene_name": "Cht5", "activity": [ { "ec_number": "3.2.1.14", "activity": "Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins.", "evidence": [ { "id": "Q9VFR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VFR3" } ] }, { "ec_number": "3.2.1.14", "activity": "", "evidence": [ { "id": "Q9VFR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VFR3" } ] } ] }, { "uniprot_ac": "Q9VGE7", "gene_name": "Ect3", "activity": [ { "ec_number": "3.2.1.23", "activity": "Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.", "evidence": [ { "id": "Q9VGE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VGE7" } ] }, { "ec_number": "3.2.1.23", "activity": "", "evidence": [ { "id": "Q9VGE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VGE7" } ] } ] }, { "uniprot_ac": "Q9VGN8", "gene_name": "Dmel\\CG5276", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "Q9VGN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VGN8" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "Q9VGN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VGN8" } ] } ] }, { "uniprot_ac": "Q9VHE4", "gene_name": "Dmel\\CG8132", "activity": [ { "ec_number": "3.5.1.3", "activity": "2-oxosuccinamate + H2O = oxaloacetate + NH4(+).", "evidence": [ { "id": "Q9VHE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VHE4" } ] }, { "ec_number": "3.5.1.3", "activity": "", "evidence": [ { "id": "Q9VHE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VHE4" } ] } ] }, { "uniprot_ac": "Q9VHP0", "gene_name": "bel", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q9VHP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VHP0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q9VHP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VHP0" } ] } ] }, { "uniprot_ac": "Q9VJ39", "gene_name": "pepCG10602", "activity": [ { "ec_number": "3.3.2.6", "activity": "leukotriene A4 + H2O = leukotriene B4.", "evidence": [ { "id": "Q9VJ39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJ39" } ] }, { "ec_number": "3.3.2.6", "activity": "", "evidence": [ { "id": "Q9VJ39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJ39" } ] } ] }, { "uniprot_ac": "Q9VLR2", "gene_name": "Dmel\\CG8353", "activity": [ { "ec_number": "3.5.4.5", "activity": "cytidine + H2O + H(+) = uridine + NH4(+).", "evidence": [ { "id": "Q9VLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VLR2" } ] }, { "ec_number": "3.5.4.5", "activity": "", "evidence": [ { "id": "Q9VLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VLR2" } ] } ] }, { "uniprot_ac": "Q9VMJ5", "gene_name": "Gal", "activity": [ { "ec_number": "3.2.1.23", "activity": "Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.", "evidence": [ { "id": "Q9VMJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMJ5" } ] }, { "ec_number": "3.2.1.23", "activity": "", "evidence": [ { "id": "Q9VMJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMJ5" } ] } ] }, { "uniprot_ac": "Q9VP22", "gene_name": "Cdk12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9VP22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VP22" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "Q9VP22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VP22" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q9VP22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VP22" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q9VP22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VP22" } ] } ] }, { "uniprot_ac": "Q9VQH0", "gene_name": "Pykl2", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "Q9VQH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQH0" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "Q9VQH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQH0" } ] } ] }, { "uniprot_ac": "Q9VQX4", "gene_name": "Naprt", "activity": [ { "ec_number": "6.3.4.21", "activity": "5-phospho-alpha-D-ribose 1-diphosphate + nicotinate + ATP + H2O = nicotinate beta-D-ribonucleotide + ADP + phosphate + diphosphate.", "evidence": [ { "id": "Q9VQX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQX4" } ] }, { "ec_number": "6.3.4.21", "activity": "", "evidence": [ { "id": "Q9VQX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQX4" } ] } ] }, { "uniprot_ac": "Q9VSA5", "gene_name": "Dmel\\CG8492", "activity": [ { "ec_number": "3.2.1.17", "activity": "Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.", "evidence": [ { "id": "Q9VSA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSA5" } ] }, { "ec_number": "3.2.1.17", "activity": "", "evidence": [ { "id": "Q9VSA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSA5" } ] } ] }, { "uniprot_ac": "Q9VSC3", "gene_name": "RNaseX25", "activity": [ { "ec_number": "4.6.1.19", "activity": "a ribonucleotidyl-ribonucleotide-RNA + H2O = a 3'-end 3'-phospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + H(+).", "evidence": [ { "id": "Q9VSC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSC3" } ] } ] }, { "uniprot_ac": "Q9VT65", "gene_name": "CalpB", "activity": [ { "ec_number": "3.4.22.-", "activity": "", "evidence": [ { "id": "Q9VT65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VT65" } ] } ] }, { "uniprot_ac": "Q9VTJ4", "gene_name": "Fuca", "activity": [ { "ec_number": "3.2.1.51", "activity": "an alpha-L-fucoside + H2O = L-fucose + an alcohol.", "evidence": [ { "id": "Q9VTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTJ4" } ] }, { "ec_number": "3.2.1.51", "activity": "", "evidence": [ { "id": "Q9VTJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTJ4" } ] } ] }, { "uniprot_ac": "Q9VTV9", "gene_name": "Pbgs", "activity": [ { "ec_number": "4.2.1.24", "activity": "2 5-aminolevulinate = porphobilinogen + 2 H2O + H(+).", "evidence": [ { "id": "Q9VTV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTV9" } ] }, { "ec_number": "4.2.1.24", "activity": "", "evidence": [ { "id": "Q9VTV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTV9" } ] } ] }, { "uniprot_ac": "Q9VUY9", "gene_name": "Pgm1", "activity": [ { "ec_number": "5.4.2.2", "activity": "alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate.", "evidence": [ { "id": "Q9VUY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUY9" } ] }, { "ec_number": "5.4.2.2", "activity": "", "evidence": [ { "id": "Q9VUY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUY9" } ] } ] }, { "uniprot_ac": "Q9VV96", "gene_name": "PGRP-SB2", "activity": [ { "ec_number": "3.5.1.28", "activity": "Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides.", "evidence": [ { "id": "Q9VV96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VV96" } ] }, { "ec_number": "3.5.1.28", "activity": "", "evidence": [ { "id": "Q9VV96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VV96" } ] } ] }, { "uniprot_ac": "Q9VVK4", "gene_name": "Adgf-B", "activity": [ { "ec_number": "3.5.4.4", "activity": "2'-deoxyadenosine + H2O + H(+) = 2'-deoxyinosine + NH4(+).", "evidence": [ { "id": "Q9VVK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVK4" } ] }, { "ec_number": "3.5.4.4", "activity": "", "evidence": [ { "id": "Q9VVK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVK4" } ] } ] }, { "uniprot_ac": "Q9VY87", "gene_name": "CtsB", "activity": [ { "ec_number": "3.4.-.-", "activity": "", "evidence": [ { "id": "Q9VY87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VY87" } ] }, { "ec_number": "3.4.22.-", "activity": "", "evidence": [ { "id": "Q9VY87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VY87" } ] } ] }, { "uniprot_ac": "Q9VYH1", "gene_name": "Fer3HCH", "activity": [ { "ec_number": "1.16.3.1", "activity": "4 Fe(2+) + O2 + 4 H(+) = 4 Fe(3+) + 2 H2O.", "evidence": [ { "id": "Q9VYH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VYH1" } ] }, { "ec_number": "1.16.3.1", "activity": "", "evidence": [ { "id": "Q9VYH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VYH1" } ] } ] }, { "uniprot_ac": "Q9VYX7", "gene_name": "PGRP-SA", "activity": [ { "ec_number": "3.4.17.13", "activity": "N-acetyl-D-glucosaminyl-N-acetylmuramoyl-L-alanyl-meso-2,6-diaminoheptanedioyl-D-alanine + H2O = N-acetyl-D-glucosaminyl-N-acetylmuramoyl-L-alanyl-meso-2,6-diaminoheptanedioate + D-alanine.", "evidence": [ { "id": "Q9VYX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VYX7" } ] }, { "ec_number": "3.4.17.13", "activity": "", "evidence": [ { "id": "Q9VYX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VYX7" } ] } ] }, { "uniprot_ac": "Q9VZV2", "gene_name": "Cht7", "activity": [ { "ec_number": "3.2.1.-", "activity": "", "evidence": [ { "id": "Q9VZV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZV2" } ] }, { "ec_number": "3.2.1.14", "activity": "Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins.", "evidence": [ { "id": "Q9VZV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZV2" } ] } ] }, { "uniprot_ac": "Q9VZZ4", "gene_name": "Pxn", "activity": [ { "ec_number": "1.11.2.-", "activity": "", "evidence": [ { "id": "Q9VZZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZZ4" } ] } ] }, { "uniprot_ac": "Q9W092", "gene_name": "Cht2", "activity": [ { "ec_number": "3.2.1.14", "activity": "Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins.", "evidence": [ { "id": "Q9W092", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W092" } ] }, { "ec_number": "3.2.1.14", "activity": "", "evidence": [ { "id": "Q9W092", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W092" } ] } ] }, { "uniprot_ac": "Q9W122", "gene_name": "Mmp1", "activity": [ { "ec_number": "3.4.24.-", "activity": "", "evidence": [ { "id": "Q9W122", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W122" } ] } ] }, { "uniprot_ac": "Q9W1K6", "gene_name": "Dmel\\CG18128", "activity": [ { "ec_number": "2.4.2.1", "activity": "adenosine + phosphate = alpha-D-ribose 1-phosphate + adenine.", "evidence": [ { "id": "Q9W1K6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W1K6" } ] }, { "ec_number": "2.4.2.1", "activity": "", "evidence": [ { "id": "Q9W1K6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W1K6" } ] } ] }, { "uniprot_ac": "Q9W2H8", "gene_name": "Agl", "activity": [ { "ec_number": "2.4.1.25", "activity": "Transfers a segment of a (1->4)-alpha-D-glucan to a new position in an acceptor, which may be glucose or a (1->4)-alpha-D-glucan.", "evidence": [ { "id": "Q9W2H8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W2H8" } ] }, { "ec_number": "3.2.1.33", "activity": "Hydrolysis of (1->6)-alpha-D-glucosidic branch linkages in glycogen phosphorylase limit dextrin.", "evidence": [ { "id": "Q9W2H8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W2H8" } ] }, { "ec_number": 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"id": "Q9VYI1", "url": "https://www.orthodb.org/?gene=Q9VYI1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12822", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12822", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12822:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12822:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04893", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04893", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001285171", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285171", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VYI1", "url": "https://www.uniprot.org/uniprotkb/Q9VYI1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VYI1-1", "url": "https://www.uniprot.org/uniprotkb/Q9VYI1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METPMADDLLQFRDYSGGAPAQINVNSPTHGGSGGSGGGSAGSGGSVGGGGANAQRQRGDPLADLIYDMTSSAQGFSGAASSGGSQPQNSSLDGSAGGGGGGAKLSLFTIEYYQQFFNVDTYMVLERIANSMIPKRASGNYLRMNIGENPDLYGPFWITVTLIFSIAISGNIASYLQQATDAYKWHYNFHLVSYAATSIFLYANILPAVLWALFKYSLKPVDSADAVETDSASYMPSLLSLMCIYGYSLAIYIPVSILWVINISLLQWLLVITAALLSGTVLIAVLTPALRNSQFSLFLIVGILSAHVVLAAGFLLYFFHNPTVPSLDPVAPTPAAPAAPAALKAVTQAVVNAVPGNQTH", "length": 360, "header": "tr|Q9VYI1-1|Q9VYI1_DROME Isoform 1 of Protein YIPF OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG4645 PE=1 SV=2 CANONICAL=Q9VYI1-1" }, "isoforms": [ { "isoform_ac": "Q9VYI1-1", "url": "https://www.uniprot.org/uniprotkb/Q9VYI1/entry#Q9VYI1-1", "sequence": { "sequence": "METPMADDLLQFRDYSGGAPAQINVNSPTHGGSGGSGGGSAGSGGSVGGGGANAQRQRGDPLADLIYDMTSSAQGFSGAASSGGSQPQNSSLDGSAGGGGGGAKLSLFTIEYYQQFFNVDTYMVLERIANSMIPKRASGNYLRMNIGENPDLYGPFWITVTLIFSIAISGNIASYLQQATDAYKWHYNFHLVSYAATSIFLYANILPAVLWALFKYSLKPVDSADAVETDSASYMPSLLSLMCIYGYSLAIYIPVSILWVINISLLQWLLVITAALLSGTVLIAVLTPALRNSQFSLFLIVGILSAHVVLAAGFLLYFFHNPTVPSLDPVAPTPAAPAAPAALKAVTQAVVNAVPGNQTH", "length": 360, "header": "tr|Q9VYI1-1|Q9VYI1_DROME Isoform 1 of Protein YIPF OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG4645 PE=1 SV=2 CANONICAL=Q9VYI1-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 333, "start_aa": "Thr", "end_pos": 333, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr333", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VYI1", "url": "https://www.uniprot.org/uniprotkb/Q9VYI1" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VYI1", "url": "https://www.uniprot.org/uniprotkb/Q9VYI1" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VYI1", "url": "https://www.uniprot.org/uniprotkb/Q9VYI1" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VYI1", "url": "https://www.uniprot.org/uniprotkb/Q9VYI1" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VYI1", "url": "https://www.uniprot.org/uniprotkb/Q9VYI1" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VYI1", "url": "https://www.uniprot.org/uniprotkb/Q9VYI1" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VYI1", "url": "https://www.uniprot.org/uniprotkb/Q9VYI1" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VYI1", "url": "https://www.uniprot.org/uniprotkb/Q9VYI1" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VYI1", "url": "https://www.uniprot.org/uniprotkb/Q9VYI1" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VYI1", "url": "https://www.uniprot.org/uniprotkb/Q9VYI1" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VYI1", "url": "https://www.uniprot.org/uniprotkb/Q9VYI1" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG4645", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG4645", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P53108-1", "protein_name": "Protein YIP5", "gene_name": "YIP5", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MPSNNSSFLDIDDDLEGVDDFGNEPNPFDDATVPDSPNMNNSTAGKGSEFYNTTGSKAESAPLQGQMDPPAYDQVIGQNDNDGLGRNGLRPGLINYYSKYFQIDLTQFKKRLSAVLTFRNDHNSESNEDNTDLYGAVWITATVVMINFTMSRGLNFIISDVIEGVKTGEDIDRASQFKKLLHSIWLFYGYTFGVPFITMQVLNRDEHSERNRSFKSVPELISVYGYANLIWIPVCVILNILDMSKRLRTVQAIQWAIVALGWAQSSYFLNSQISSNNNTETQSNGKFSLSIIVVVALHTLFCLLFRFIIF", "length": 310 }, "evidence": [ { "id": "RGD:1307512", "url": "https://alliancegenome.org/gene/RGD:1307512#orthology", "database": "AGR" }, { "id": "MGI:1915532", "url": "https://alliancegenome.org/gene/MGI:1915532#orthology", "database": "AGR" }, { "id": "MGI:1922016", "url": "https://alliancegenome.org/gene/MGI:1922016#orthology", "database": "AGR" }, { "id": "HGNC:28476", "url": "https://alliancegenome.org/gene/HGNC:28476#orthology", "database": "AGR" }, { "id": "HGNC:25231", "url": "https://alliancegenome.org/gene/HGNC:25231#orthology", "database": "AGR" }, { "id": "RGD:735206", "url": "https://alliancegenome.org/gene/RGD:735206#orthology", "database": "AGR" }, { "id": "FB:FBgn0030435", "url": "https://alliancegenome.org/gene/FB:FBgn0030435#orthology", "database": "AGR" }, { "id": "SGD:S000003129", "url": "https://alliancegenome.org/gene/SGD:S000003129#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q5XIT3-1", "protein_name": "Protein YIPF2", "gene_name": "Yipf2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAADDLAFHEFEEAANLLAETPDAATTSQSDKLTSQEHVAVVVGSGIGYGAEGEEEDDKTSLLQDEKPQPRFWTFDYYQSFFDVDTSQVLDRIKGSLLPHPGHNFVRHHLRNRPDLYGPFWICATLAFVLAVTGNLTLVLAQRRDPSIHYSPQFHKVTIAGITIYCYAWLVPLALWGFLRWRQGTRERMGLYTFLETVCVYGYSLFVFIPTVVLWLIPVQWLQWLFGALALALSAAGLVFTLWPVVREDTRLVAAALLSIVVLLHALLALGCKLYFFQPLPLDHVVPAPQAIPPSPNVLLPSSVQPMTTF", "length": 311 }, "evidence": [ { "id": "RGD:1307512", "url": "https://alliancegenome.org/gene/RGD:1307512#orthology", "database": "AGR" }, { "id": "MGI:1922016", "url": "https://alliancegenome.org/gene/MGI:1922016#orthology", "database": "AGR" }, { "id": "HGNC:28476", "url": "https://alliancegenome.org/gene/HGNC:28476#orthology", "database": "AGR" }, { "id": "FB:FBgn0030435", "url": "https://alliancegenome.org/gene/FB:FBgn0030435#orthology", "database": "AGR" }, { "id": "SGD:S000003129", "url": "https://alliancegenome.org/gene/SGD:S000003129#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6P6G5-1", "protein_name": "Protein YIPF1", "gene_name": "Yipf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAVDDLQFEEFGDGATLLAANPDATTINIEDPSVSFKHQPRPPGSLGREEDEELLGTNDSDETELLAGQKKSSPFWTFEYYQTFFDVDTYQVFDRIKGSLLPVPGKNFVRLYIRSNPDLYGPFWICATLVFAIAISGNLSNFLIHLGEKTYHYVPEFQKVSIAATVIYAYAWLVPLALWGFLLWRNSKVMNIVSYSFLEIVCVYGYSLFIYIPTAVLWIIPQRVIRWVLVTIALGISGSVLAMTFWPAVREDNRRVALATIVTIMLLHVLLSVGCLAYFFDAPEMDHLPAAITTPNQTVAAAKSS", "length": 306 }, "evidence": [ { "id": "MGI:1915532", "url": "https://alliancegenome.org/gene/MGI:1915532#orthology", "database": "AGR" }, { "id": "HGNC:25231", "url": "https://alliancegenome.org/gene/HGNC:25231#orthology", "database": "AGR" }, { "id": "RGD:735206", "url": "https://alliancegenome.org/gene/RGD:735206#orthology", "database": "AGR" }, { "id": "FB:FBgn0030435", "url": "https://alliancegenome.org/gene/FB:FBgn0030435#orthology", "database": "AGR" }, { "id": "SGD:S000003129", "url": "https://alliancegenome.org/gene/SGD:S000003129#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q91VU1-1", "protein_name": "Protein YIPF1", "gene_name": "Yipf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAVDDLQFEEFGDGATLLAANPDATTINIEDPSVSFGHQPRPPGSVGREEDEELLGNNDSDETELLAGQKRSSPFWTFEYYQTFFDVDTYQVFDRIKGSLLPVPGKNFVRLYIRSNPDLYGPFWICATLVFAIAISGNLSNFLIHLGEKTYHYVPEFQKVSIAATVIYAYAWLVPLALWGFLLWRNSKVMSMVSYSFLEIVCVYGYSLFIYIPTAVLWIIPQRVVRWVLVMIALGVSGSVLVMTFWPAVREDNRRVALATIVTIVLLHVLLSVGCLAYFFDAPEMDHLPAAITTPNQTVTAAKSS", "length": 306 }, "evidence": [ { "id": "MGI:1915532", "url": "https://alliancegenome.org/gene/MGI:1915532#orthology", "database": "AGR" }, { "id": "HGNC:25231", "url": "https://alliancegenome.org/gene/HGNC:25231#orthology", "database": "AGR" }, { "id": "RGD:735206", "url": "https://alliancegenome.org/gene/RGD:735206#orthology", "database": "AGR" }, { "id": "FB:FBgn0030435", "url": "https://alliancegenome.org/gene/FB:FBgn0030435#orthology", "database": "AGR" }, { "id": "SGD:S000003129", "url": "https://alliancegenome.org/gene/SGD:S000003129#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q99LP8-1", "protein_name": "Protein YIPF2", "gene_name": "Yipf2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAADELAFHEFEEATNLLAETPDAATTSQSDELTSREHVAVVVGSGIGYGAEVGEEEDDKTSLLQEEKPQPRFWTFDYYQSFFDVDTSQVLDRIKGSLLPHPGHNFVRHHLRNRPDLYGPFWICATLAFVLAVTGNLTLVLAQRRDPSIHYSPQFHKVTIAGITIYCYAWLVPLALWGFLRWRQGTRERMGLYTFLETVCVYGYSLFVFIPTVVLWLIPVQWIQWLFGALGLALSAAGLVFTLWPVVREDTRLVAAALLSTVVLLHALLALGCKLYFFQPLPLDHVVPAPQATPPSPNVLLPSSIQPMTTS", "length": 312 }, "evidence": [ { "id": "RGD:1307512", "url": "https://alliancegenome.org/gene/RGD:1307512#orthology", "database": "AGR" }, { "id": "MGI:1922016", "url": "https://alliancegenome.org/gene/MGI:1922016#orthology", "database": "AGR" }, { "id": "HGNC:28476", "url": "https://alliancegenome.org/gene/HGNC:28476#orthology", "database": "AGR" }, { "id": "FB:FBgn0030435", "url": "https://alliancegenome.org/gene/FB:FBgn0030435#orthology", "database": "AGR" }, { "id": "SGD:S000003129", "url": "https://alliancegenome.org/gene/SGD:S000003129#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BWQ6-1", "protein_name": "Protein YIPF2", "gene_name": "YIPF2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASADELTFHEFEEATNLLADTPDAATTSRSDQLTPQGHVAVAVGSGGSYGAEDEVEEESDKAALLQEQQQQQQPGFWTFSYYQSFFDVDTSQVLDRIKGSLLPRPGHNFVRHHLRNRPDLYGPFWICATLAFVLAVTGNLTLVLAQRRDPSIHYSPQFHKVTVAGISIYCYAWLVPLALWGFLRWRKGVQERMGPYTFLETVCIYGYSLFVFIPMVVLWLIPVPWLQWLFGALALGLSAAGLVFTLWPVVREDTRLVATVLLSVVVLLHALLAMGCKLYFFQSLPPENVAPPPQITSLPSNIALSPTLPQSLAPS", "length": 316 }, "evidence": [ { "id": "RGD:1307512", "url": "https://alliancegenome.org/gene/RGD:1307512#orthology", "database": "AGR" }, { "id": "MGI:1922016", "url": "https://alliancegenome.org/gene/MGI:1922016#orthology", "database": "AGR" }, { "id": "HGNC:28476", "url": "https://alliancegenome.org/gene/HGNC:28476#orthology", "database": "AGR" }, { "id": "FB:FBgn0030435", "url": "https://alliancegenome.org/gene/FB:FBgn0030435#orthology", "database": "AGR" }, { "id": "SGD:S000003129", "url": "https://alliancegenome.org/gene/SGD:S000003129#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Y548-1", "protein_name": "Protein YIPF1", "gene_name": "YIPF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAVDDLQFEEFGNAATSLTANPDATTVNIEDPGETPKHQPGSPRGSGREEDDELLGNDDSDKTELLAGQKKSSPFWTFEYYQTFFDVDTYQVFDRIKGSLLPIPGKNFVRLYIRSNPDLYGPFWICATLVFAIAISGNLSNFLIHLGEKTYHYVPEFRKVSIAATIIYAYAWLVPLALWGFLMWRNSKVMNIVSYSFLEIVCVYGYSLFIYIPTAILWIIPQKAVRWILVMIALGISGSLLAMTFWPAVREDNRRVALATIVTIVLLHMLLSVGCLAYFFDAPEMDHLPTTTATPNQTVAAAKSS", "length": 306 }, "evidence": [ { "id": "MGI:1915532", "url": "https://alliancegenome.org/gene/MGI:1915532#orthology", "database": "AGR" }, 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"id": "FB:FBgn0030432", "url": "https://alliancegenome.org/gene/FB:FBgn0030432", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0030432", "url": "https://bgee.org/?page=gene&gene_id=FBgn0030432", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0030432", "url": "https://flybase.org/reports/FBgn0030432", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "32241", "url": "https://www.ncbi.nlm.nih.gov/gene/32241", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039353", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039353", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG4404", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG4404", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WQHVANE", "url": "https://omabrowser.org/oma/group/WQHVANE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VYI4", "url": "https://www.orthodb.org/?gene=Q9VYI4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12243", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12243", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12243:SF60", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12243:SF60", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02944", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02944", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10545", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10545", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_572838", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572838", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VYI4", "url": "https://www.uniprot.org/uniprotkb/Q9VYI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VYI4-1", "url": "https://www.uniprot.org/uniprotkb/Q9VYI4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCWVAMARKDDPVFNVRFVQFVENQPCLWNYTHPGYSKKEDVQRAWQQVANDIKDTVRNCRERWRTIRSSFLRSLKLARTQTGRGKRKYYLSKYLQFLVPFTKSRSCHKQLPGMVLRKPGQAATAQQEDEVVAAEEEAKVSDGEMPLDVQVSEEEHRRNQEQDREQPTACLPLRLHSIKVEHDSSNANQQLERMVSQQSLVSVPAAALGNHLGWSDLTQWFKGHGSGHHKLTTTTTTPTSPPPPPQPATSALSVFTGGPGGGGSQPDADYSFLISLHPYIKEMNGKQNRKFRQKVVGLIDDILDNKDV", "length": 308, "header": "tr|Q9VYI4-1|Q9VYI4_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG4404 PE=4 SV=2 CANONICAL=Q9VYI4-1" }, "isoforms": [ { "isoform_ac": "Q9VYI4-1", "url": "https://www.uniprot.org/uniprotkb/Q9VYI4/entry#Q9VYI4-1", "sequence": { "sequence": "MCWVAMARKDDPVFNVRFVQFVENQPCLWNYTHPGYSKKEDVQRAWQQVANDIKDTVRNCRERWRTIRSSFLRSLKLARTQTGRGKRKYYLSKYLQFLVPFTKSRSCHKQLPGMVLRKPGQAATAQQEDEVVAAEEEAKVSDGEMPLDVQVSEEEHRRNQEQDREQPTACLPLRLHSIKVEHDSSNANQQLERMVSQQSLVSVPAAALGNHLGWSDLTQWFKGHGSGHHKLTTTTTTPTSPPPPPQPATSALSVFTGGPGGGGSQPDADYSFLISLHPYIKEMNGKQNRKFRQKVVGLIDDILDNKDV", "length": 308, "header": "tr|Q9VYI4-1|Q9VYI4_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG4404 PE=4 SV=2 CANONICAL=Q9VYI4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VYI4", "url": "https://www.uniprot.org/uniprotkb/Q9VYI4" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VYI4", "url": "https://www.uniprot.org/uniprotkb/Q9VYI4" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VYI4", "url": "https://www.uniprot.org/uniprotkb/Q9VYI4" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", 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[7227]" } ], "gene": [ { "name": "Coq8", "url": "https://www.uniprot.org/uniprotkb/Q9VYI6", "locus": { "chromosome": "X", "start_pos": 12898768, "end_pos": 12901114, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0052649", "url": "https://www.ensemblgenomes.org/id/FBgn0052649" } ] } } ], "crossref": [ { "id": "FB:FBgn0052649", "url": "https://alliancegenome.org/gene/FB:FBgn0052649", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0052649", "url": "https://bgee.org/?page=gene&gene_id=FBgn0052649", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13970", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13970", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0052649", "url": "https://flybase.org/reports/FBgn0052649", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "32239", "url": "https://www.ncbi.nlm.nih.gov/gene/32239", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004147", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004147", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034646", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034646", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051409", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051409", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG32649", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG32649", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PEYYVPR", "url": "https://omabrowser.org/oma/group/PEYYVPR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VYI6", "url": "https://www.orthodb.org/?gene=Q9VYI6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43851", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43851", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43851:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43851:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03109", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03109", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-2142789", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-2142789", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_572836", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572836", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VYI6", "url": "https://www.uniprot.org/uniprotkb/Q9VYI6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VYI6-1", "url": "https://www.uniprot.org/uniprotkb/Q9VYI6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRSAQEAAALLRGLRILLEACGREHLAHGRHLWSNSSIRELIAENVAHTQQLVRSSSQNPTEELKKLQQTVKETGERGYVVAKGICSLLETKIKMSREESAISEPAQVSSIRKSTPTAQNPASWDAANLDISSITLQEFEEILSRRNKDRSVSLRTPATKSNQTMPKKETSTNPGIITQDTEYVNNVLRFVAGAKVEEQPPDAQPKKKSDQPAIEVPELSKVAKQRKVPSSRIGRMASFGGLFAGLGLGTLNELTKGALGLGGSTSMREALLSPANAERIVDTLCKVRGAALKIGQILSIQDSSVVSPQLAKAFERVRQAADYMPDWQVERVMNTQLGADWRQRLKSFEDKPFAAASIGQVHRATLSDGMDVAIKIQYPGVAQSIESDIDNLVGMLKVWDVFPQGFFIDNVVRVAKRELQWEVDYDREAEYTEKFREMIAPYPEYYVPRVVRDLTTSSVLTTELVPGVPLDKCFDLSYEHRRHIAASVLKLCLRELFEIECMQTDPNWSNFLYDAPSRRLMLIDFGSTRFYRHEFIRNYRRVIMSAAENNRQGVLEMSREMGFLTGYETKQMEQAHVDAVMILGEIFRYDGDFDFGRQNTTERLAALVPTMVAHRLCPPPEEIYSIHRKLSGIFLLCARLNVRMNCVPFYKDIVLGKFKD", "length": 661, "header": "tr|Q9VYI6-1|Q9VYI6_DROME Isoform 1 of Coenzyme Q8 OS=Drosophila melanogaster OX=7227 GN=Coq8 PE=1 SV=2 CANONICAL=Q9VYI6-1" }, "isoforms": [ { "isoform_ac": "Q9VYI6-1", "url": "https://www.uniprot.org/uniprotkb/Q9VYI6/entry#Q9VYI6-1", "sequence": { "sequence": "MSRSAQEAAALLRGLRILLEACGREHLAHGRHLWSNSSIRELIAENVAHTQQLVRSSSQNPTEELKKLQQTVKETGERGYVVAKGICSLLETKIKMSREESAISEPAQVSSIRKSTPTAQNPASWDAANLDISSITLQEFEEILSRRNKDRSVSLRTPATKSNQTMPKKETSTNPGIITQDTEYVNNVLRFVAGAKVEEQPPDAQPKKKSDQPAIEVPELSKVAKQRKVPSSRIGRMASFGGLFAGLGLGTLNELTKGALGLGGSTSMREALLSPANAERIVDTLCKVRGAALKIGQILSIQDSSVVSPQLAKAFERVRQAADYMPDWQVERVMNTQLGADWRQRLKSFEDKPFAAASIGQVHRATLSDGMDVAIKIQYPGVAQSIESDIDNLVGMLKVWDVFPQGFFIDNVVRVAKRELQWEVDYDREAEYTEKFREMIAPYPEYYVPRVVRDLTTSSVLTTELVPGVPLDKCFDLSYEHRRHIAASVLKLCLRELFEIECMQTDPNWSNFLYDAPSRRLMLIDFGSTRFYRHEFIRNYRRVIMSAAENNRQGVLEMSREMGFLTGYETKQMEQAHVDAVMILGEIFRYDGDFDFGRQNTTERLAALVPTMVAHRLCPPPEEIYSIHRKLSGIFLLCARLNVRMNCVPFYKDIVLGKFKD", "length": 661, "header": "tr|Q9VYI6-1|Q9VYI6_DROME Isoform 1 of Coenzyme Q8 OS=Drosophila melanogaster OX=7227 GN=Coq8 PE=1 SV=2 CANONICAL=Q9VYI6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VYI6", "url": "https://www.uniprot.org/uniprotkb/Q9VYI6" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VYI6", "url": "https://www.uniprot.org/uniprotkb/Q9VYI6" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VYI6", "url": "https://www.uniprot.org/uniprotkb/Q9VYI6" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VYI6", "url": "https://www.uniprot.org/uniprotkb/Q9VYI6" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VYI6", "url": "https://www.uniprot.org/uniprotkb/Q9VYI6" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VYI6", "url": "https://www.uniprot.org/uniprotkb/Q9VYI6" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VYI6", "url": "https://www.uniprot.org/uniprotkb/Q9VYI6" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VYI6", "url": "https://www.uniprot.org/uniprotkb/Q9VYI6" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VYI6", "url": "https://www.uniprot.org/uniprotkb/Q9VYI6" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VYI6", "url": "https://www.uniprot.org/uniprotkb/Q9VYI6" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VYI6", "url": "https://www.uniprot.org/uniprotkb/Q9VYI6" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG32649", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG32649", "resource": "KEGG Pathway" }, { "id": "R-DME-2142789", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-2142789", "resource": "Reactome", "description": "Ubiquinol biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2R212-1", "protein_name": "Atypical kinase COQ8A, mitochondrial", "gene_name": "COQ8A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAVLGDALMLVKGLVKLTQAAVETHLQHLGLGGELVLLARTLQSTAAEQMGVIWGQVQGQERHEEPHSESFDDPQAEFHFSGPRVEDFSAAASSEQAQDHTSSQGPAPAYAASGPFREGGFPGQAAHPLGGVNRRLFADPRDPFSSTGLQRRFLHQDQSPVGGLTAEDIEKARQAKARPESKPHKQMLSERARERKVPVTRIGRLANFGGLAVGLGFGALAEVAKKSLRPEDPSGKKAVLDSSPFLSEANAERIVRTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFERVRQSADFMPLKQMMVRRGGRRAALGAGVGVLGGFSGGPRPCSWPPPGISLQKTLNKDLGPSWRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQYPGVAQSINSDVNNLMAVLNMSNMLPEGLFPEHLIDVLRRELALECDYQREAACARKFRELLKDHPFFYVPEIVDELCSPHVLTTELVSGFPLDQAEGLSQEIRNEICYNILVLCLRELFEFHFMQTDPNWSNFFYDPQQHRVALLDFGATREYDRSFTDLYIQVIRAAADQDREAVLKKSIEMKFLTGYEVKAMEDAHLDAILILGEAFASEEPFDFGTQSTTEKIHNLIPIMLKHRLVPPPEETYSLHRKMGGSFLICSKLKARFPCKAMFEEAYSNYRRRQAEQQ", "length": 677 }, "evidence": [ { "id": "Q9VYI6", "url": "https://omabrowser.org/oma/group/Q9VYI6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A3QJU3-1", "protein_name": "Atypical kinase COQ8B, mitochondrial", "gene_name": "coq8b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLLSEVLQVLRGAGKVGAAFTSTQGEQLRLMACNSTFGAGMKAAAEAVEGVMGTVMGGGDMTSKTDEFAGIEKWEEMDLDEAAKWSVASEMPPDFSSKDGRGETSETPVGAATGTIKGAGWPAQNTRFLHVSASQHHFRFVHDSIVARLSPEDIQRAREAKQNIARPVRQKLNERAKERKVPATRISRLANFGGLAVGLGIGAIAEVAKQSFGGKRSEVGALLDSPLLSEANAERIVNTLCKVRGAALKIGQMLSIQDNSFINPQLQKIFERVRQSADFMPAWQMHKVLEEELGSGWREKLSSIEEKPFAAASIGQVHHGVLPGGKEIAMKIQYPGVAESIHSDINNLMSVLKMSVVLPDGLFADSSLEVLQRELAWECDYEREAKCAKRFRNLLKGDPVFVVPEVFDELSARRVITMELVNGVPLDRCVDLDQETRNEICFNILQLCLRELFEFRFMQTDPNWSNFFYNSEQNKIFLLDFGACRDYPELFTDHYIEVVHAASVGDRATVLKKSKDLKFLTGFEAKAFEDAHVEAVMILGEAFASAEAFDFGTQSTTQRIQSLIPVMLRHRLTPPPEESYSLHRKMAGSFLICSKLKARFSCRNMFLDVYNAYKRQQQERRSQV", "length": 624 }, "evidence": [ { "id": "MGI:1924139", "url": "https://alliancegenome.org/gene/MGI:1924139#orthology", "database": "AGR" }, { "id": "HGNC:19041", "url": "https://alliancegenome.org/gene/HGNC:19041#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-803", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-803#orthology", "database": "AGR" }, { "id": "FB:FBgn0052649", "url": "https://alliancegenome.org/gene/FB:FBgn0052649#orthology", "database": "AGR" }, { "id": "RGD:1311356", "url": "https://alliancegenome.org/gene/RGD:1311356#orthology", "database": "AGR" }, { "id": "SGD:S000003087", "url": "https://alliancegenome.org/gene/SGD:S000003087#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7F0M3-1", "protein_name": "Atypical kinase COQ8A, mitochondrial", "gene_name": "coq8ab", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVKMAADMLLMRGINRFRNIRFRGRQKQVSFLTPQLRGQVSCGHQTALSFSGVMGVFGSDQHLSRLFGKIHPDQQHIYSQIGFFHQDHRYYSALKKEGVKGVKADSRKHNQKLSESARERKMPVTRIGRLVNFGGLAVGLGIGAIAEVAKKSFASRDNSGQKKAILDSNPFISEANAERIVRTLCKVRGAALKLGQMLSIQDDAFINPQLAKIFERVRQSADFMPAKQTMKMVVSDLGPNWQDHLEYFEERPFAAASIGQVHLARMKDGREVAMKIQYPGVAKSISSDINNLLTLLSISHALPEGLFPEHLIEVMSRELALECDYIREAKCAKKFQQLLKGHPFFSVPNVVDELSSKHVLTTELVSGFPLDKAEDLPQELKNEICEQILILCLRELFEFRYMQTDPNWSNFFFDPQTHKVALLDFGATRGFDASFTDTYIEIIKAAADRNREGVLQRSIDMKFLTGYESKSMVNAHVDAVMILGEAFSSDEPFDFGSQSTTERIHRLIPVMLKERLTPPPEETYSLHRKMGGSFLICSRLKAQICCKNMFQEAYAKYWRERHKETAQ", "length": 567 }, "evidence": [ { "id": "RGD:1308245", "url": "https://alliancegenome.org/gene/RGD:1308245#orthology", "database": "AGR" }, { "id": "MGI:1914676", "url": "https://alliancegenome.org/gene/MGI:1914676#orthology", "database": "AGR" }, { "id": "HGNC:16812", "url": "https://alliancegenome.org/gene/HGNC:16812#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-5543", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-5543#orthology", "database": "AGR" }, { "id": "FB:FBgn0052649", "url": "https://alliancegenome.org/gene/FB:FBgn0052649#orthology", "database": "AGR" }, { "id": "SGD:S000003087", "url": "https://alliancegenome.org/gene/SGD:S000003087#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1NGM2-1", "protein_name": "Atypical kinase COQ8A, mitochondrial", "gene_name": "COQ8A", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGDAIMVMRGLTKLSKAVLETQAGQLRQVILGGDAVTIAKSLQATAEEQFSSALGKMQELGKQQENLSDFSEDFGKDYDFLAQEPPDASRDFSTAPSKPHEHSSEGPAYSYTTNGPFKSVGETGDSGLGQKPFPPKMDAKLFGGFRDPGNPFAAVFGQNRAFHQDHSSVGGLTAEDIDKARQAKTEQKPYKQMLSERARERKVPVTRIGRLANFGGLAVGLGIGALAEVAKKSLRPEERSGKKAVMDSSPFLSEANAERIVRTLCKVRGAALKLGQMLSIQDDAFINPHLQRIFERVRQSADFMPIKQMMKTLNNDLGPNWRDKLESFEERPFAAASIGQVHLARLKNGKEVAMKIQYPGVAQSINSDVNNLMTVLSMSNILPEGLFPEHLIEVLSRELALECDYQREAACAKKFQELLKDHPFFYVPRVVDELCSKHVLTTELVSGFPLDQAVGLSQEIRNEICHNILVLCLRELFEFRYMQTDPNWSNFFYDPQLHKVALLDFGATRGFDEKFTDVYIEVIKAAADMDRERVLKKSIEMKFLTGYEVKEMEDAHLNAVLILGEAFASEEPFDFGNQSTTEKIHGLIPVMLKHRLVPPPEETYSLHRKMGGSFLICTKLKAKIPCKNMFEEAYSKYWSNRGKKPED", "length": 648 }, "evidence": [ { "id": "Q9VYI6", "url": "https://omabrowser.org/oma/group/Q9VYI6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3HV77-1", "protein_name": "Atypical kinase COQ8A, mitochondrial", "gene_name": "Coq8a", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAAMLGDAIMVAKGLAKLTQAAVETHLQNLGLGGELILAARALQSTAVEQISMVFGKVQGQDKHEDLYATENFEDLEAEVQFSTPQAAETSLDFSATSSPDQSLSSSLGHAHSEGPAPTYVSSGPFREAGLSGQATSPMGRVNGRLFVNTRDLFLASGIQRRFFHQDQSPVGGLTAEDIEKARQAKARPESKPHKQMLSERARERKVPVTRIGRLANFGGLAVGLGFGALAEVAKKSLRPENSTGKKAVLDSSPFLSEANAERIVSTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFERVRQSADFMPLKQMTKTLNNDLGPHWRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQYPGVAQSINSDVNNLMAVLNMSNMLPEGLFPEHLIDVLRRELVLECDYQREAAYAKKFRELLKDHPFFYVPEIVDELCSPHVLTTELITGFPLDQAEGLSQEVRNEICYNILVLCLRELFEFHVMQTDPNWSNFFYDPQQHKVALLDFGATREYDRSFTDLYIQVIRAAADQDREAVLKKSIEMKFLTGYEVKAMEDAHLDAILILGEAFASEEPFDFGTQSTTEKIHNLIPVMLKHRLIPPPEETYSLHRKMGGSFLICSKLKARFPCKTMFEEAYSNYCRMKSGLQ", "length": 649 }, "evidence": [ { "id": "Q9VYI6", "url": "https://omabrowser.org/oma/group/Q9VYI6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P27697-1", "protein_name": "Atypical kinase COQ8, mitochondrial", "gene_name": "COQ8", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVTNMVKLRNLRRLYCSSRLLRTIQNGRISSVSSISLSKKYTTKSAKEGEENVERKHEEEKKDTLKSSSVPTSRISRLFHYGSLAAGVGMNAAAKGISEVAKGNSPTWKSLILSDSNIDRITNKFSKMRGVALKIGQLLSFQDEKVLPKELYEILSRVQNSANHMPQRQLEKVMAKELGANWKTKFSKFDKIPMAAASIGQVHAAELPSGQRVVVKIQYPGVKESIDSDLNSLLMLLTASSLLPKGLFLDKTIANARTELKWECDYNREARALQKFEALLKDDPAFEVPHVFPEYTTDNIITMTRMEGTEIMKLPKASQETKNFISENIMRLCLEEIATFKYMQTDPNWANFLYNGRTKKIELLDFGASRPFAEDFILKYRKLLTYATLRDRKGAYEMSVQLGYLTGLESQSMKDAHVDSVLTLGEPFRGDVDKSFDFKDQTVSDRIRGNIGLMLNERLCPPPEETYSLHRKFSGIFLLCARMGASVHCAKLFKEIFAYKV", "length": 501 }, "evidence": [ { "id": "RGD:1308245", "url": "https://alliancegenome.org/gene/RGD:1308245#orthology", "database": "AGR" }, { "id": "MGI:1924139", "url": "https://alliancegenome.org/gene/MGI:1924139#orthology", "database": "AGR" }, { "id": "MGI:1914676", "url": "https://alliancegenome.org/gene/MGI:1914676#orthology", "database": "AGR" }, { "id": "HGNC:19041", "url": "https://alliancegenome.org/gene/HGNC:19041#orthology", "database": "AGR" }, { "id": "HGNC:16812", "url": "https://alliancegenome.org/gene/HGNC:16812#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-803", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-803#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-5543", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-5543#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040718-487", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040718-487#orthology", "database": "AGR" }, { "id": "FB:FBgn0052649", "url": "https://alliancegenome.org/gene/FB:FBgn0052649#orthology", "database": "AGR" }, { "id": "RGD:1311356", "url": "https://alliancegenome.org/gene/RGD:1311356#orthology", "database": "AGR" }, { "id": "SGD:S000003087", "url": "https://alliancegenome.org/gene/SGD:S000003087#orthology", "database": "AGR" }, { "id": "Q9VYI6", "url": "https://omabrowser.org/oma/group/Q9VYI6/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q29RI0-1", "protein_name": "Atypical kinase COQ8A, mitochondrial", "gene_name": "COQ8A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAMLGDAIMLIKGFVKLTQAAVETHLQHLGLSGELLMAVRALQSTATEQVGMVFGQVQGQETPEEYYSESLDDPEGAFHFSGMRAESASADVSAASSPEQSPPPWAHAAGSEGPAPAYVASAPFREGGVLGQAASPLGRVNGRLFASPRDPFSAPGLQRRVYHQDQSSMGGLTAEDIEKARQAKARPESKPHKQALSEHARERKVPVTRIGRLANFGGLAVGLGFGALAEVAKKSLRPDDPSGKKAVLDSSPFLSEANAERIVRTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFDRVRQSADFMPLKQMMKTLNNDLGPNWRDKLEYFEERPFAAASIGQVHLARLKGGREVAMKIQYPGVAQSINSDVNNLMTVLNMSNMLPEGLFPEHLIDVLRRELALECDYQREAACARRFRELLKDHPFFYVPEIVDELCSPHVLTTELVSGFPLDQAEGLSQEIRNEICYNILVLCLRELFEFQFMQTDPNWSNFFYDPELHKVALLDFGATREFDRSFTDLYIQIIRAAANQDREAVLKKSIEMKFLTGYEVKAMEDAHLDAILILGEAFASEEPFDFGTQSTTEKIHNLIPIMLKHRLVPPPEETYSLHRKMGGSFLICSKLKARFPCKAMFEEAYSNYCRRQAEQQ", "length": 648 }, "evidence": [ { "id": "Q9VYI6", "url": "https://omabrowser.org/oma/group/Q9VYI6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54IH6-1", "protein_name": "Probable serine/threonine-protein kinase abkA", "gene_name": "abkA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGGRLNDLIQVAYGGKNVILSMMKNKTRQTSSVFINNLNSLNNNNNNISLKDKFKDLKDLKDNLNEKKINNDNDDDDEDNLIFDEKKDFLNENKNPELNYIKSKGHKIPSSQTSRFWEFTKLAVGVGAGFLGEKTKRTIDSSSSSSSPSSSYSAIFTDTNAERMAESFSRMRGAALKIGQVLSIQDESFLPPKFVEILDRVRKNANPIPLEQLYNTMSNELGENWRSKFQLFQDDPIAAASIGQVHRAITLDGKEVAVKVQYPGVADSITSDIKNLSSLLKMIVPETAYIEKSLESARSELLLETDYLNEASNQLKFKSLLESSINSGTNGSFKYLKDLYVPNVIMELTTKRILTTEFVHGTSIDKITIENHNQETRDWISKNILSLCLAELFEFNFMQVDPNWTNFVVDFENKRINLLDFGACRNYKSEFLFNYLKSIEGGVNRDINQILEYSLKLGYLTGDENKQMNDAQAKSILILSEPFSKLYYKENNLKTYPFNEKQIAKRISQLIPTMLKNRLKPPPEETYSLHRKLSGCYLVCSKLKSNINSTLIFNHFKNIFYKNYK", "length": 565 }, "evidence": [ { "id": "Q9VYI6", "url": "https://omabrowser.org/oma/group/Q9VYI6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q566J8-1", "protein_name": "Atypical kinase COQ8B, mitochondrial", "gene_name": "Coq8b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWLELGAMLRRTCGPLGRAVRLPCGGALGPRPHWWGPCRSCLAQSVHQDQPGRGLSEDDIRRAREARLRKAPRPQLSDRSRERKVPASRISRLASFGGLAVGLGLGALAEVTKKSLPGGSLQHEGVSGLGSSPFLSEANAERIVQTLCTVRGAALKIGQMLSIQDNSFISPQLQRIFERVRQSADFMPRWQMMRVLEEELGKDWQDKVASLEEVPFAAASIGQVHQGLLKDGTEVAVKIQYPGVAQSIQSDVENLLALLKMSVGLPEGLFAEQSLQTLQQELAWECDYRREAACAQTFRKLLADDPFFRVPAVVQELCTTRVLGMELAGGIPLDQCQGLSQDIRNQICFQLLRLCLRELFEFRFMQTDPNWANFLYDASSHQVTLLDFGASRAFGTEFTDHYIEVVKAAADGDRDRVLQKSQDLKFLTGFETKAFSDAHVEAVMILGEPFAASGPYDFGAGETARRIQGLIPVLLRHRLRPPPEETYALHRKLAGAFLACARLHAHIACRDLFQDTYHRYWASRQTLPLPAAS", "length": 533 }, "evidence": [ { "id": "MGI:1924139", "url": "https://alliancegenome.org/gene/MGI:1924139#orthology", "database": "AGR" }, { "id": "HGNC:19041", "url": "https://alliancegenome.org/gene/HGNC:19041#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-803", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-803#orthology", "database": "AGR" }, { "id": "FB:FBgn0052649", "url": "https://alliancegenome.org/gene/FB:FBgn0052649#orthology", "database": "AGR" }, { "id": "RGD:1311356", "url": "https://alliancegenome.org/gene/RGD:1311356#orthology", "database": "AGR" }, { "id": "SGD:S000003087", "url": "https://alliancegenome.org/gene/SGD:S000003087#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5BJQ0-1", "protein_name": "Atypical kinase COQ8A, mitochondrial", "gene_name": "Coq8a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAMLGDAIMVAKGLAKLTQAAVETHLQNLGLGGELILAARALQSTAVEQISMVFGKVQGQDKHEDSYATENFEDLEAEVQFSTPQAAGSSPDFSTASSLDQPLSSSLGHAHREGPAPAYVSSGPFREAGLSGQATSPLGRVNGRLFVDCRDLFLANSIQRRFFHQDQAPVGGLTAEDIEKARQAKARPESKPHKQMLSERARERKVPVTRIGRLANFGGLAVGLGFGALAEVAKKSLRSENSTGKKAVLDSSPFLSEANAERIVSTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFERVRQSADFMPLKQMTKTLNNDLGPHWRDKLEYFEERPFAAASIGQVHLARLKGGREVAMKIQYPGVAQSINSDVNNLMAVLNMSNMLPEGLFPEHLIDVLRRELTLECDYQREAAYAKKFRELLKDHPFFYVPEIVDELCSPHVLTTELITGFPLDQAEGLSQEVRNEICYNILVLCLRELFEFHVMQTDPNWSNFFYDPQQHKVALLDFGATREYDRSFTDLYIQVIRAAADQDREAVLKKSIEMKFLTGYEVKAMEDAHLDAILILGEAFASEEPFDFGTQSTTEKIHNLIPIMLKHRLIPPPEETYSLHRKMGGSFLICSKLKACFPCKAMFEEAYSNYCRMKSGLQ", "length": 649 }, "evidence": [ { "id": "RGD:1308245", "url": "https://alliancegenome.org/gene/RGD:1308245#orthology", "database": "AGR" }, { "id": "MGI:1914676", "url": "https://alliancegenome.org/gene/MGI:1914676#orthology", "database": "AGR" }, { "id": "HGNC:16812", "url": "https://alliancegenome.org/gene/HGNC:16812#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-5543", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-5543#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040718-487", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040718-487#orthology", "database": "AGR" }, { "id": "FB:FBgn0052649", "url": "https://alliancegenome.org/gene/FB:FBgn0052649#orthology", "database": "AGR" }, { "id": "SGD:S000003087", "url": "https://alliancegenome.org/gene/SGD:S000003087#orthology", "database": "AGR" }, { "id": "Q9VYI6", "url": "https://omabrowser.org/oma/group/Q9VYI6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5RGU1-1", "protein_name": "Atypical kinase COQ8A, mitochondrial", "gene_name": "coq8a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAGDMLLLMRGLARLSQAVIETQANSLRSGGVQTMQMTAEQAMGVAMQKIQEFTGSQQSVSDFSADMDSKYDFTASEQNFESAAHGGLDSDSVFRDANTGAANTYSQAQGKSKLFDGYKDPTSQFTGHTRSYHQDHSSVGGITAEDIEKAREAKQNGSKPHKQMLSERARERKVPVTRLGRLANFGGLAVGLGIGALAEVAKKSLRSEDKNGNKKAVLDSSPFLSEANAERIVRTLCKVRGAALKLGQMLSIQDDAFINPQLAKIFERVRQSADFMPIKQMTKALSNDLGPNWRDKLEMFEERPFAAASIGQVHLARMKDGREVAMKIQYPGVAQSINSDVNNLMTVLSMSNALPEGLFPEHLIDVMRRELALECDYIREAKCARKFKELLKDHPFFYVPDVISELSSQHVLTTELVPGFPLDQAEALTQELKNEICKNILNLCLRELFEFRYMQTDPNWSNFFYDPQTHRVALLDFGATRGFDESFTDVYIEIIKAAADGNREGVLKQSIDMKFLTGYESKAMVNAHVDAVMILGEAFASEEPFDFGAQSTTERIHNLIPVMLKQRLIPPPEETYSLHRKMGGSFLICSRLNAKISCKDMFEAAYSNYWSGRKKGPSQ", "length": 619 }, "evidence": [ { "id": "RGD:1308245", "url": "https://alliancegenome.org/gene/RGD:1308245#orthology", "database": "AGR" }, { "id": "MGI:1914676", "url": "https://alliancegenome.org/gene/MGI:1914676#orthology", "database": "AGR" }, { "id": "HGNC:16812", "url": "https://alliancegenome.org/gene/HGNC:16812#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040718-487", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040718-487#orthology", "database": "AGR" }, { "id": "FB:FBgn0052649", "url": "https://alliancegenome.org/gene/FB:FBgn0052649#orthology", "database": "AGR" }, { "id": "SGD:S000003087", "url": "https://alliancegenome.org/gene/SGD:S000003087#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q60936-1", "protein_name": "Atypical kinase COQ8A, mitochondrial", "gene_name": "Coq8a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAMLGDAIMVAKGLAKLTQAAVETHLQNLGLGGELLLAARALQSTAVEQFSMVFGKVQGQDKHEDSYATENFEDLEAEVQFSTPQAAGTSLDFSAASSLDQSLSPSHSQGPAPAYASSGPFREAGLPGQATSPMGRVNGRLFVDHRDLFLANGIQRRSFHQDQSSVGGLTAEDIEKARQAKARPESKPHKQMLSERARERKVPVTRIGRLANFGGLAVGLGIGALAEVAKKSLRSENSTGKKAVLDSSPFLSEANAERIVSTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFERVRQSADFMPLKQMTKTLNSDLGPHWRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQYPGVAQSINSDVNNLMAVLNMSNMLPEGLFPEHLIDVLRRELTLECDYQREAAYAKKFRELLKDHPFFYVPEIVDELCSPHVLTTELISGFPLDQAEGLSQEVRNEICYNILVLCLRELFEFHVMQTDPNWSNFFYDPQQHKVALLDFGATREYDRSFTDLYIQVIRAAADQDREAVLKKSIEMKFLTGYEVKAMEDAHLDAILILGEAFASEEPFDFGTQSTTEKIHNLIPVMLKHRLIPPPEETYSLHRKMGGSFLICSKLKARFPCKAMFEEAYSNYCRMKSGLQ", "length": 645 }, "evidence": [ { "id": "RGD:1308245", "url": "https://alliancegenome.org/gene/RGD:1308245#orthology", "database": "AGR" }, { "id": "MGI:1914676", "url": "https://alliancegenome.org/gene/MGI:1914676#orthology", "database": "AGR" }, { "id": "HGNC:16812", "url": "https://alliancegenome.org/gene/HGNC:16812#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-5543", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-5543#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040718-487", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040718-487#orthology", "database": "AGR" }, { "id": "FB:FBgn0052649", "url": "https://alliancegenome.org/gene/FB:FBgn0052649#orthology", "database": "AGR" }, { "id": "SGD:S000003087", "url": "https://alliancegenome.org/gene/SGD:S000003087#orthology", "database": "AGR" }, { "id": "Q9VYI6", "url": "https://omabrowser.org/oma/group/Q9VYI6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6AY19-1", "protein_name": "Atypical kinase COQ8B, mitochondrial", "gene_name": "Coq8b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWLELGAMLRTTCGPLGRAVRLPCAGALRLRPHWWGPCRDCLAQRVHQDQPGRGLTEDEIRRAREARLRKAPRPQLSDRSRERKVPASRISRLASFGGLAVGLGLGALAEVTKKSLPGGSLQHEGSSPFLTEANAERIVQTLCTVRGAALKIGQMLSIQDNSLISPQLQRVFERVRQSADFMPRWQMMKVLEEELGKDWQDKVASLEEVPFAAASIGQVHQGVLKDGTEVAVKIQYPGVAESIQSDVQNLLALLKMSVGLPEGLFAEQSLQTLQQELAWECDYRREAACAQTFKKLLADDPFFRVPAVVEELCTTRVLGMELAGGIPLDQCQGLSQDIRNQICFQLLRLCLRELFEFRFMQTDPNWANFLYDASSHKVTLLDFGASRAFGTEFTDHYIEVVKAAADGDRDRVLQKSQDLKFLTGFETKAFSDAHVEAVMILGEPFAASGSYDFGAGETARRIQGLIPVLLRHRLRPPPEETYALHRKLAGAFLACARLHAHIACRDLFQDTYHRYWASRQTLPLPAAS", "length": 528 }, "evidence": [ { "id": "MGI:1924139", "url": "https://alliancegenome.org/gene/MGI:1924139#orthology", "database": "AGR" }, { "id": "HGNC:19041", "url": "https://alliancegenome.org/gene/HGNC:19041#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-803", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-803#orthology", "database": "AGR" }, { "id": "FB:FBgn0052649", "url": "https://alliancegenome.org/gene/FB:FBgn0052649#orthology", "database": "AGR" }, { "id": "RGD:1311356", "url": "https://alliancegenome.org/gene/RGD:1311356#orthology", "database": "AGR" }, { "id": "SGD:S000003087", "url": "https://alliancegenome.org/gene/SGD:S000003087#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8NI60-1", "protein_name": "Atypical kinase COQ8A, mitochondrial", "gene_name": "COQ8A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAILGDTIMVAKGLVKLTQAAVETHLQHLGIGGELIMAARALQSTAVEQIGMFLGKVQGQDKHEEYFAENFGGPEGEFHFSVPHAAGASTDFSSASAPDQSAPPSLGHAHSEGPAPAYVASGPFREAGFPGQASSPLGRANGRLFANPRDSFSAMGFQRRFFHQDQSPVGGLTAEDIEKARQAKARPENKQHKQTLSEHARERKVPVTRIGRLANFGGLAVGLGFGALAEVAKKSLRSEDPSGKKAVLGSSPFLSEANAERIVRTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFERVRQSADFMPLKQMMKTLNNDLGPNWRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQYPGVAQSINSDVNNLMAVLNMSNMLPEGLFPEHLIDVLRRELALECDYQREAACARKFRDLLKGHPFFYVPEIVDELCSPHVLTTELVSGFPLDQAEGLSQEIRNEICYNILVLCLRELFEFHFMQTDPNWSNFFYDPQQHKVALLDFGATREYDRSFTDLYIQIIRAAADRDRETVRAKSIEMKFLTGYEVKVMEDAHLDAILILGEAFASDEPFDFGTQSTTEKIHNLIPVMLRHRLVPPPEETYSLHRKMGGSFLICSKLKARFPCKAMFEEAYSNYCKRQAQQ", "length": 647 }, "evidence": [ { "id": "RGD:1308245", "url": "https://alliancegenome.org/gene/RGD:1308245#orthology", "database": "AGR" }, { "id": "MGI:1914676", "url": "https://alliancegenome.org/gene/MGI:1914676#orthology", "database": "AGR" }, { "id": "HGNC:16812", "url": "https://alliancegenome.org/gene/HGNC:16812#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-5543", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-5543#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040718-487", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040718-487#orthology", "database": "AGR" }, { "id": "FB:FBgn0052649", "url": "https://alliancegenome.org/gene/FB:FBgn0052649#orthology", "database": "AGR" }, { "id": "SGD:S000003087", "url": "https://alliancegenome.org/gene/SGD:S000003087#orthology", "database": "AGR" }, { "id": "Q9VYI6", "url": "https://omabrowser.org/oma/group/Q9VYI6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q96D53-1", "protein_name": "Atypical kinase COQ8B, mitochondrial", "gene_name": "COQ8B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWLKVGGLLRGTGGQLGQTVGWPCGALGPGPHRWGPCGGSWAQKFYQDGPGRGLGEEDIRRAREARPRKTPRPQLSDRSRERKVPASRISRLANFGGLAVGLGLGVLAEMAKKSMPGGRLQSEGGSGLDSSPFLSEANAERIVQTLCTVRGAALKVGQMLSIQDNSFISPQLQHIFERVRQSADFMPRWQMLRVLEEELGRDWQAKVASLEEVPFAAASIGQVHQGLLRDGTEVAVKIQYPGIAQSIQSDVQNLLAVLKMSAALPAGLFAEQSLQALQQELAWECDYRREAACAQNFRQLLANDPFFRVPAVVKELCTTRVLGMELAGGVPLDQCQGLSQDLRNQICFQLLTLCLRELFEFRFMQTDPNWANFLYDASSHQVTLLDFGASREFGTEFTDHYIEVVKAAADGDRDCVLQKSRDLKFLTGFETKAFSDAHVEAVMILGEPFATQGPYDFGSGETARRIQDLIPVLLRHRLCPPPEETYALHRKLAGAFLACAHLRAHIACRDLFQDTYHRYWASRQPDAATAGSLPTKGDSWVDPS", "length": 544 }, "evidence": [ { "id": "MGI:1924139", "url": "https://alliancegenome.org/gene/MGI:1924139#orthology", "database": "AGR" }, { "id": "HGNC:19041", "url": "https://alliancegenome.org/gene/HGNC:19041#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-803", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-803#orthology", "database": "AGR" }, { "id": "FB:FBgn0052649", "url": "https://alliancegenome.org/gene/FB:FBgn0052649#orthology", "database": "AGR" }, { "id": "RGD:1311356", "url": "https://alliancegenome.org/gene/RGD:1311356#orthology", "database": "AGR" }, { "id": "SGD:S000003087", "url": "https://alliancegenome.org/gene/SGD:S000003087#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9SBB2-1", "protein_name": "Protein ABC transporter 1, mitochondrial", "gene_name": "ABC1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSWSKSFTRLVNGVSLVAKEIYNQSPELQRARNGDLEGLITSSGKKALVAATDLVGLTSGKLRELSIRRSKEPSVVYFDEGDNKDNVVATPEVRSVNTKPSEKIVDSKVLRNEFSDEVKNSNREGEIKVSGVEAGEIIGVRAVESGTVTEASSPSEVVPPVKRRRPRERKVPSTPMARAYGFFNLGAALAWGAVKESTYRMVNGTPMTPDNQPALSSLMSKENAERLALGLCEMRGAALKVGQMLSIQDESLVPAPILNALEYVRQGADVMPRSQLNPVLDAELGSNWQSKLTSFDYEPLAAASIGQVHRAVTKDGLEVAMKIQYPGVANSIESDIENVRRLLNYTNLIPKGLFLDRAIKVAKEELAQECDYEIEAVSQKRFRDLLSDTPGFYVPLVVDETSSKKILTTELISGIPIDKVALLDQKTRDYVGRKMLELTLKELFVFRFMQTDPNWGNFLYNEATKTINLIDFGAARDYPKKFVDDYLRMVMACAEKDSEGVIEMSRRLGFLTGDESDVMLDAHVQAGFIVGLPFAEPGGYAFRTNNIASSISNLGATMLKHRLSPPPDEAYSLHRKLSGAFLACIKLGATVPCRDLLLQVYNKYQFDDEPQDPVVATSSVSS", "length": 623 }, "evidence": [ { "id": "Q9VYI6", "url": "https://omabrowser.org/oma/group/Q9VYI6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extrinsic component of mitochondrial inner membrane", "id": "GO:0031314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031314", "evidence": [ { "database": "UniProtKB", "id": "Q9VYI6", "url": "https://www.uniprot.org/uniprotkb/Q9VYI6" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9VYI6", "url": "https://www.uniprot.org/uniprotkb/Q9VYI6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "Q9VYI6", "url": "https://www.uniprot.org/uniprotkb/Q9VYI6" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VYI6", "url": "https://www.uniprot.org/uniprotkb/Q9VYI6" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "Q9VYI6", "url": "https://www.uniprot.org/uniprotkb/Q9VYI6" } ], "pmid": "" }, { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "Q9VYI6", "url": "https://www.uniprot.org/uniprotkb/Q9VYI6" } ], "pmid": "" }, { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "Q9VYI6", "url": "https://www.uniprot.org/uniprotkb/Q9VYI6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "ubiquinone biosynthetic process", "id": "GO:0006744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006744", "evidence": [ { "database": "UniProtKB", "id": "Q9VYI6", "url": "https://www.uniprot.org/uniprotkb/Q9VYI6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": 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[], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 163, "end_pos": 165 }, { "start_pos": 36, "end_pos": 38 }, { "start_pos": 508, "end_pos": 510 }, { "start_pos": 600, "end_pos": 602 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": 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"table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VYJ3-1", "uniprot_ac": "Q9VYJ3", "uniprot_id": "Q9VYJ3_DROME", "mass": { "chemical_mass": 25439.0, "monoisotopic_mass": 25439.0 }, "refseq": { "ac": "NP_001285168", "name": "uncharacterized protein, isoform C", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285168" }, "gene_names": [ { "name": "CG15723", "type": "recommended", "evidence": 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VYJ3" } ] }, { "name": "CG3794", "type": "synonym", "evidence": [ { "id": "NP_001285168", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285168" }, { "id": "Q9VYJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VYJ3" } ] }, { "name": "CT35953", "type": "synonym", "evidence": [ { "id": "NP_001285168", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285168" }, { "id": "Q9VYJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VYJ3" } ] }, { "name": "Dmel\\CG32647", "type": "synonym", "evidence": [ { "id": "NP_001285168", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285168" }, { "id": "Q9VYJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VYJ3" } ] }, { "name": "Dmel_CG32647", "type": "synonym", "evidence": [ { "id": "Q9VYJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VYJ3" } ] } ], "protein_names": [ { "name": "Integral membrane protein DGCR2/IDD", "type": "recommended", "evidence": [ { "id": "Q9VYJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VYJ3/entry#names_and_taxonomy" } ] }, { "name": "CG32647-PC", "type": "synonym", "evidence": [ { "id": "NP_001285168", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285168" } ] }, { "name": "uncharacterized protein, isoform C", "type": "synonym", "evidence": [ { "id": "NP_001285168", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285168" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VYJ3", "url": "https://www.uniprot.org/uniprotkb/Q9VYJ3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "CG15723", "url": "https://www.uniprot.org/uniprotkb/Q9VYJ3", "locus": { "chromosome": "X", "start_pos": 12771844, "end_pos": 12784958, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0052647", "url": "https://www.ensemblgenomes.org/id/FBgn0052647" } ] } } ], "crossref": [ { "id": "FB:FBgn0052647", "url": "https://alliancegenome.org/gene/FB:FBgn0052647", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0052647", "url": "https://bgee.org/?page=gene&gene_id=FBgn0052647", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0052647", "url": "https://flybase.org/reports/FBgn0052647", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "326226", "url": "https://www.ncbi.nlm.nih.gov/gene/326226", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR042378", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042378", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG32647", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG32647", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MTAASTW", "url": "https://omabrowser.org/oma/group/MTAASTW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VYJ3", "url": "https://www.orthodb.org/?gene=Q9VYJ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15256", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15256", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15256:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15256:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "NP_001285168", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285168", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VYJ3", "url": "https://www.uniprot.org/uniprotkb/Q9VYJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VYJ3-1", "url": "https://www.uniprot.org/uniprotkb/Q9VYJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTKAAAAAATATATTTAAATPIKTAAATKAITINGPQTTWRRQRGCCTTTTTAAIRNMQQQKQKQQQQSYLQRLKAAGRLGAWPPPMTSLLWLPTDYLAQLILALCLLGCLSPFTAALEEDCVDFQGNKVNHGMLYVPGPGVCSLCVCYHSEPLWCKAIYCDPPYFCKNFRVGERCCEFECLDPPGEDKLYQERMRKRAEILAGNSTASNVQLAPIAMSTIMLGFLGNSFLNL", "length": 233, "header": "tr|Q9VYJ3-1|Q9VYJ3_DROME Isoform 1 of Integral membrane protein DGCR2/IDD OS=Drosophila melanogaster OX=7227 GN=CG15723 PE=4 SV=2 CANONICAL=Q9VYJ3-1" }, "isoforms": [ { "isoform_ac": "Q9VYJ3-1", "url": "https://www.uniprot.org/uniprotkb/Q9VYJ3/entry#Q9VYJ3-1", "sequence": { "sequence": "MTKAAAAAATATATTTAAATPIKTAAATKAITINGPQTTWRRQRGCCTTTTTAAIRNMQQQKQKQQQQSYLQRLKAAGRLGAWPPPMTSLLWLPTDYLAQLILALCLLGCLSPFTAALEEDCVDFQGNKVNHGMLYVPGPGVCSLCVCYHSEPLWCKAIYCDPPYFCKNFRVGERCCEFECLDPPGEDKLYQERMRKRAEILAGNSTASNVQLAPIAMSTIMLGFLGNSFLNL", "length": 233, "header": "tr|Q9VYJ3-1|Q9VYJ3_DROME Isoform 1 of Integral membrane protein DGCR2/IDD OS=Drosophila melanogaster OX=7227 GN=CG15723 PE=4 SV=2 CANONICAL=Q9VYJ3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VYJ3", "url": "https://www.uniprot.org/uniprotkb/Q9VYJ3" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VYJ3", "url": "https://www.uniprot.org/uniprotkb/Q9VYJ3" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VYJ3", "url": "https://www.uniprot.org/uniprotkb/Q9VYJ3" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VYJ3", "url": "https://www.uniprot.org/uniprotkb/Q9VYJ3" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VYJ3", "url": "https://www.uniprot.org/uniprotkb/Q9VYJ3" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VYJ3", "url": "https://www.uniprot.org/uniprotkb/Q9VYJ3" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VYJ3", "url": "https://www.uniprot.org/uniprotkb/Q9VYJ3" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VYJ3", "url": "https://www.uniprot.org/uniprotkb/Q9VYJ3" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VYJ3", "url": "https://www.uniprot.org/uniprotkb/Q9VYJ3" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VYJ3", "url": "https://www.uniprot.org/uniprotkb/Q9VYJ3" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VYJ3", "url": "https://www.uniprot.org/uniprotkb/Q9VYJ3" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG32647", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG32647", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LK94-1", "protein_name": "Integral membrane protein DGCR2/IDD", "gene_name": "Dgcr2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRPWLYPPIRVSIFHSHSSTVLSLVGILGLWWRGNSELELRCHPGQFACHSGIIQCIPLPWQCDGWPTCEDKSDEADCPEVTGEARPYGKETVDLRQGRTRGGDPTHFHTVNVAQPVRFSRKCPSGWHHYEGTASCYRVYLSGENYWDAAQTCQRVNGSLATFSTDQELRFVLAQEWDQPERSFGWKDQRKLWVGYQYVITGRNHSLEGRWEVAFKGSPEVFLPPDPIFASAMSENDNVFCAQLQCFHFPTLRHHDLHSWHAESCSEKSSFLCKRSQTCVDIKDNVVDEGFYFTPKGDDPCLSCTCHRGEPEMCVAALCERPQGCQQYRKDPKECCKFMCLDPDGSSLFDSMASGMRLVVSCVSSFLILSLLLFMVHRLRQRRRERIESLIGANLHHFNLGRRIPGFDYGPDGFGTGLTPLHLSDDGEGGTFHFHDPPPPYTAYKCPDLDQPDDPPPPYEASINPDSVFYDPADDDAFEPVEASLPTPRDGGIEGALPRHLDQPLPPAETSLADLEDSTDSSSALLVPPDPAQSGSTPATEAPPGAGRLSRGSLNTVV", "length": 559 }, "evidence": [ { "id": "HGNC:2845", "url": "https://alliancegenome.org/gene/HGNC:2845#orthology", "database": "AGR" }, { "id": "RGD:1310567", "url": "https://alliancegenome.org/gene/RGD:1310567#orthology", "database": "AGR" }, { "id": "MGI:892866", "url": "https://alliancegenome.org/gene/MGI:892866#orthology", "database": "AGR" }, { "id": "FB:FBgn0052647", "url": "https://alliancegenome.org/gene/FB:FBgn0052647#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P98153-1", "protein_name": "Integral membrane protein DGCR2/IDD", "gene_name": "DGCR2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVPKADSGAFLLLFLLVLTVTEPLRPELRCNPGQFACRSGTIQCIPLPWQCDGWATCEDESDEANCPEVTGEVRPHHGKEAVDPRQGRARGGDPSHFHAVNVAQPVRFSSFLGKCPTGWHHYEGTASCYRVYLSGENYWDAAQTCQRLNGSLATFSTDQELRFVLAQEWDQPERSFGWKDQRKLWVGYQYVITGRNRSLEGRWEVAFKGSSEVFLPPDPIFASAMSENDNVFCAQLQCFHFPTLRHHDLHSWHAESCYEKSSFLCKRSQTCVDIKDNVVDEGFYFTPKGDDPCLSCTCHGGEPEMCVAALCERPQGCQQYRKDPKECCKFMCLDPDGNSLFDSMASGMRLVVSCISSFLILSLLLFMVHRLRQRRRERIESLIGANLHHFNLGRRIPGFDYGPDGFGTGLTPLHLSDDGEGGTFHFHDPPPPYTAYKYPDIGQPDDPPPPYEASIHPDSVFYDPADDDAFEPVEVSLPAPGDGGSEGALLRRLEQPLPTAGASLADLEDSADSSSALLVPPDPAQSGSTPAAEALPGGGRHSRSSLNTVV", "length": 550 }, "evidence": [ { "id": "HGNC:2845", "url": "https://alliancegenome.org/gene/HGNC:2845#orthology", "database": "AGR" }, { "id": "RGD:1310567", "url": "https://alliancegenome.org/gene/RGD:1310567#orthology", "database": "AGR" }, { "id": "MGI:892866", "url": "https://alliancegenome.org/gene/MGI:892866#orthology", "database": "AGR" }, { "id": "FB:FBgn0052647", "url": "https://alliancegenome.org/gene/FB:FBgn0052647#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P98154-1", "protein_name": "Integral membrane protein DGCR2/IDD", "gene_name": "Dgcr2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVPKADSGAFLLLFLLVLTVTEPLRPELRCNPGQFACHGGTIQCIPLPWQCDGWPTCEDKSDEADCPVTGEARPYGKETVDLRQGRARGGDPTHFHTVNVAQPVRFSSFLGKCPSGWHHYEGTASCYRVYLSGENYWDAAQTCQRVNGSLATFSTDQELRFVLAQEWDQPERSFGWKDQRKLWVGYQYVITGRNHSLEGRWEVAFKGSPEVFLPPDPIFASAMSENDNVFCAQLQCFHFPTLRHHDLHSWHAESCSEKSSFLCKRSQTCVDIKDNVVDEGFYFTPKGDDPCLSCTCHRGEPEMCVAALCERPQGCQQYRKDPKECCKFMCLDPDGSSLFDSMASGMRLVVSCISSFLILSLLLFMVHRLAQRRRERIESLIGANLHHFNLGRRIPGFDYGPDGFGTGLTPLHLSDDGEGGTFHFHDPPPPYTAYKYPDMDQPDDPPPPYEASINPDSVFYDPADDDAFEPVEASLPAPRDGGIEGALPRHLDQPLPPAETSLADLEDSTDSSSALLVPPDPAQSGSTPATEAPPGGGRLPRASLNTVV", "length": 548 }, "evidence": [ { "id": "HGNC:2845", "url": "https://alliancegenome.org/gene/HGNC:2845#orthology", "database": "AGR" }, { "id": "RGD:1310567", "url": "https://alliancegenome.org/gene/RGD:1310567#orthology", "database": "AGR" }, { "id": "MGI:892866", "url": "https://alliancegenome.org/gene/MGI:892866#orthology", "database": "AGR" }, { "id": "FB:FBgn0052647", "url": "https://alliancegenome.org/gene/FB:FBgn0052647#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VFA8-1", "protein_name": "VWFC domain-containing protein", "gene_name": "lincRNA.S6902", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MYFLALLAFIGNAKDGNAVSSSLIPGGSCRDYNGKMYETGMHYMPGPDSCRLCICDSGLPKACKMVLCEAFSKCKSFQTVGSGNNCCEVICLDDQFSDGSTDFGIXLVASGITATLSLSLLFFLVNRLRQRKMRARENRQNAEDQRSIVGSIGYIAGNMGYMEGNLSAIDYSYSGAATHYPLWKPHFPRGEAPPPYEEAVAISQAEALSAQCTVSLPASSQRTVATVSQQQQQAVAQAQAQAQAQAQAQQQQQIQAQVQAHQHLQQHTLQLHTQPQQHHQPYSQQLVAHPHPQHPHSTANVLPQSNQYTQSTTNLINININSGGVTTIATGENHQPPYSLQSDHQLSLEQQQQQQQQQQHLMQPPVSSGSICLQAMPKPPVSAECSYKNCHLNISASVTTAAASSSSAAYTSGRRTTPRGSQELLHQLPQQQQQQQQQQQQQYLTVADVEINASASAASYHSLPAGSGELVATPTHAQVLQHQQQQHQQQQQHLLAAISSPGMEILQPLEIATISSAPACSTADSVTQTTQMPLHGTLKNSQPQQMSKTPSSSRRYHRTIPRYFAVADPLQLKPKTSSSATSTGDKQQASKKPMCQCPIQHVPMSYMGSTANANAFLSGAGKLFTGNSTSSSTSTPTCSLSPGAAATGGVRHAATLSYGQRAKSSSNLQAQDLITAAASGGGTLRRSGCGHEPKIATISKQVGDETHHGHTASSGGVNVSAIIPPPPLQHPEEVSAPPIVLGRVQKRSSSNSAERGRSSSGGGSGGRSVSSGSGGDSLSSVYLNRKVDAYLSLTQKQQQHFFNQQQQQQQPDPSNPTLPPKLYKSLTNLKSATVVSTSSSSCSSGSGNNNAVATIYTLSKPATSGQRKEQTPSLTLPPASPAAGQSGEKLTSGKINSSTFYPLANHVTYTLPKHISGKVSLNSTINSVVSKVPSVISIPPVENNNPGGQTGVPAKSTTLPKILRVKRDPSSGSGEGGTATSLAIAHCQMPSYPLTTKATNGGGGSTGRSPSKQLPVCTTSKNCLNPKEHFLPNDTSLDDDYLSECENCKIAQSAKYFLDAEMSGGGSANSHQETMTLQRKSLEETKEEPMESYYRSSHTLPSNAKKHGKNNNREKWQVSTIPAASSSDEDINE", "length": 1133 }, "evidence": [ { "id": "MGI:892866", "url": "https://alliancegenome.org/gene/MGI:892866#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9VYJ3", "url": "https://www.uniprot.org/uniprotkb/Q9VYJ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 205, "end_pos": 207, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 205, "end_pos": 207 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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OS=Drosophila melanogaster OX=7227 GN=pira PE=3 SV=3 CANONICAL=Q9VYJ5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VYJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VYJ5" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VYJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VYJ5" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VYJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VYJ5" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VYJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VYJ5" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VYJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VYJ5" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VYJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VYJ5" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VYJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VYJ5" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VYJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VYJ5" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VYJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VYJ5" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VYJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VYJ5" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VYJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VYJ5" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG12717", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG12717", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M2B8Q7-1", "protein_name": "Sentrin-specific protease 7b isoform X1", "gene_name": "senp7b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPDTYRESFRQACALLFLQMAVSFRIPKKKQPSDSCSLDMQSPLSRLQDDNSQKSQWGSVTFNGRTPHKTSSNENMLSKDSQRSDSLRGATRGRFSFKMNQQPIKISPARVNGTPHKVSDTSGFRPQCQTPTTAPDFTANNRWRPKRASDRLLSHDENHTKASECSAFKIHRGLDSEELEEEETEGTQGHSQVKETQRATSSEDYKVTSAASVFEKATSKHKNGTEKAVSKPFNHSGLHVQEAPARHLRTSEERAASSVPVRKDPLTSETAENKSKDPFASFYSSKLRRKPQSFCKTYKRTKPSSTEPIVLSSDDEGANEVNDVSGGLQEQRISEGIRDTQTGNQKSSKTNVGGERSTTKVEVPSIMELEFSRLHYDTIQAQANGTVVITDEGISIPLKDADGEGEVAISISCSQLQMYGMWDGGLASDGSLLSITEEPAPSLFFLMVSDAQARLLRKELSLQYNTHTSGQACPFVLLVLSGQLDDLRVALLASLMDVIGLRYAQDSLSNPVSWADGLSRLLCHPRGEHFLSLLGQNCKDTGQDKAKENASGIKEPTARRPLRSHSKPQSLPRRLIQYPPPPSKGGITVTTEDLECLKDGEFLNDVIIDFYLKYLLLERADKDIAERSHIFSSFFYKQLTRKDTSGPEETGSTSAYRRHQRVRTWTRHVDIFSKDYLFIPVNHEAHWYLVLICFPALERPQIVEWRQKSSVSQDESQTTKERPSGESQRESSQQPKGNPSKINESRSHNLPDCTVHSCTKETICKRPCILIMDSLKLSYHQRTYTLLREYLQVEWEVRKGSCRSFSNESITGSLCRVPLQDNSSDCGLYLLQYVESFLQNPVVDFALPLRLDQWFPRSQVRKKREDLRELVLLLYRRQTEPRAT", "length": 884 }, "evidence": [ { "id": "MGI:1913565", "url": "https://alliancegenome.org/gene/MGI:1913565#orthology", "database": "AGR" }, { "id": "HGNC:30402", "url": "https://alliancegenome.org/gene/HGNC:30402#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060531-45", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060531-45#orthology", "database": "AGR" }, { "id": "FB:FBgn0030420", "url": "https://alliancegenome.org/gene/FB:FBgn0030420#orthology", "database": "AGR" }, { "id": "RGD:1305510", "url": "https://alliancegenome.org/gene/RGD:1305510#orthology", "database": "AGR" }, { "id": "SGD:S000001293", "url": "https://alliancegenome.org/gene/SGD:S000001293#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PPP9-1", "protein_name": "Sentrin-specific protease 6 isoform X1", "gene_name": "senp6a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNNKKSPFIEALDKCEDRRDGGFKQTWRCSLSDDSEDDSRHDAALVTMERVSGQQELSSEGIKTPSSTKRFSANGSVETHDRRPHQLKPLNRTGKLSDAAHSVSMSPLPNRTSFLIMSPAPQAVVVQGRVFQHAQLSTPIRKLEHRSDLIQRGQMDSIVLTCPEISDPGDLSIKRRVHQKRRIGESPVTVSQVVEQPLQPDDYLTVCGECGQPSEDHVKCDHCGFILPNETKPRPAIPSALLPRPSIRPQPASLQISKGFYECSQQLDVIVNPSVRITPGNLLFPHNGRPSGSLACNGHKAAGGAKQQLNKPCELNDPIVLSSDEDDESDNMSSTGTANRLDSVSPRPADSAHSSPAPSDGRLEAVVKAAGEHEDSSADFFTHTNHRNLLPRRNRMKDPFGNLVSDDATVSKRRKINQEQKLSSIILECRSVRIGTLRRMVTKPVVFTVDFIQLETEGREVDVLESVSLKSSELTRCEWCNVKKLPVLFLQTSDQECQRLQTQLQMSQDSGGIWYDCNGNNDEKYIVLIFEHGPSMHEQVILEDILTEIGRNNRLADFPSKISFDEANVRLVNYNKASLEKEKVKVEKAEVVAAPSSSALLATPSLSVVTVAVAPVNTAPAVPVPCAAPSVQTRLSARLQEFCDDDDEMAELQPTFTGPIIKLLVYPPPPAKGGITVTNEDLHCLSDGEFLNDVIIDFYLKYLFLEKLKKEDAARSHVFSSFFYKRLNQRERRNTVDTSSLPIQKRKHNRVKTWTRHVDLFQKDFIFVPINESAHWYLAVICFPGLESAQVEPNPLYQPQTAVSSSPPTDGASEQRDQFSQNTAGPHRADANQVQFTDGLRRIIEYSTEDDSHQSDDQSSCQDECSEDGALADDSGSFDRAEWTSKPTICKQPCILIMDSLRGPTRSTVVKTLREYLEVEWEVKKGSKRSFGKELMKGSSPRVPQQDNFSDCGVYVLQYVESFFESPLPSFHLPMNLLEWFPQQRMKTKREEIKDLILKLQTQQQLSLESSEQTDGAHSPYEDSLESADLIPSVSS", "length": 1036 }, "evidence": [ { "id": "FB:FBgn0030420", "url": "https://alliancegenome.org/gene/FB:FBgn0030420#orthology", "database": "AGR" }, { "id": "HGNC:20944", "url": "https://alliancegenome.org/gene/HGNC:20944#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080204-25", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080204-25#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9QBG7-1", "protein_name": "Sentrin-specific protease 7 isoform X1", "gene_name": "si:dkey-100n23.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPDERKHNSTLSDSSNITPERRRALILSPEIKRDSRQTECPYKIARRGSAAEDECVETEMSKDRKSNNKIHWTQLASNGTSSQLSPKSTKKSNQELTILQKIHRNQVKVVLEDVLLTELGQSLLRCSGHTFQKTNQSESKKRSDQTSTPTLKNKTRTSLTKRGETNSTEPKATSPFHNNIESKSKSLNSSQKLLESSELSSNSRSPRESESPQAALISKESPIQTSSSSFEENEVTLIEGSLQNEEVLSAVCESVISSSSPVETRRRPREKKADSELLSNKKERRESQESPKDAAKHEENHLCSNGELVQEVEGMRGSVLRLSAGTDFQIPVKRCRLDSLSEDQLLNSDLAFDTAEIRSFTLESSNFSQDETIVLSSEEEDEGEGREETKISALNIQPPEGTKDTNVVDESTTVYEQTKSPESNLSITEMSEEESQGIPLPLSSLHMGGVSAKSSGIMMITPYKITFSLKGNSSDSTVKISLSAINVYKYSLWEEHTLWGCDLDKDNEATPTSLLFLWLSDAQAHKLHDDLSVLELGTRPAESSTCLLLCMAEPLSGIESALLCSLLDIVVSNQGSPELYCTCLTQSDSLNLLQSSEETHLLQLLTPKPDEQTSTSAQSQDSDVQLEPTYTLCHRRAQGSYNVFLAATPGAEWTPYKHCGPTRRLIQFPPPPSKGALTVTTEDLECLDSGEFLNDVIIDFYLKYLLVQKAPQASVARSHIFSSFFYKQLTRRDNANEDSTSTPAQVRRHQRVRTWTRHVDIFEKDFLFVPVNQEAHWYLVVICFPGLEDPQYVKRDDSASVQGNGGEDVGESENETQGDHRSNSDEDKSTDDSRIKSSTSLRQPDCTENTCKKDVVLKRPCILIMDSLKLSIHERIFKLLREYLQVEWETKRMGTRDFSAERMVGSHCKVPLQDNSSDCGLYLLQYAESFLQDPVVHFDLPLRLERWFPRQQVRGKRDEIRDLILHLYRFQKGSLGNDAADDRTDYGNVIK", "length": 991 }, "evidence": [ { "id": "MGI:1913565", "url": "https://alliancegenome.org/gene/MGI:1913565#orthology", "database": "AGR" }, { "id": "HGNC:30402", "url": "https://alliancegenome.org/gene/HGNC:30402#orthology", "database": "AGR" }, { "id": "FB:FBgn0030420", "url": "https://alliancegenome.org/gene/FB:FBgn0030420#orthology", "database": "AGR" }, { "id": "RGD:1305510", "url": "https://alliancegenome.org/gene/RGD:1305510#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-345", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-345#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58HPH5-1", "protein_name": "Sentrin-specific protease 6 isoform X1", "gene_name": "senp6b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVRPLGQNRKNSLKVKPLKGNATGLNLLGMRTILANQTPSLVKTKGKRFIYALQSSWMKESRTDLSNSQSIDVCVIEDNETTDVLKHSVKDTQLEDFYSDILDHKKSTFKENDNTSLKILRKYRMRDEFGNLNPRVKRKTPAAKKKEPNSQIAQRLNSLMLNIRCLKVGTLTKTFARSGSLSTQCTFTVDCIEISSEAGRIEASDIVACEWCTVPRLPALFLQTTYEARLHLQVQLDMLEDDSEHFQNKNEKETCIVLIFENELTLPEQIILEDIFTEIGMRHNISGFLVKLPFEEANNKLKAQISAQKQIAMLHLEEDELPASSQRALMPFPPSPDAPRHEIATLSISDSDENDLMEGHSSPVQDLKKLLVYPPSPAKGGITVTEEDFYCLDEGEFLNDVIVDFYLRYLVCKQQEKKDTTQYHVFSSFFFKHLTQGNQKRHSGATSLSPQECRHDRVKTWTRNVNLFEKDFVFVPINQMSHWYLAVICFPGQISQTSGLDLSLNERRHSRQYLCAPSPPNPMSLFYSPESSKQLSRWSQSIDDLDQSFEILSDDEAEDDLQVVTNRSVLNRGSDVSKKPCILIMDSLTSSGRSSEVQILQQYLQEEWRVKMGSQQSFEKMHGWSPIVPKQDNYTDCGIYLLQYVESFLKDPPQAFHHNMDLKGWFSQRTVKRKRLQIKELILKLHRQQ", "length": 689 }, "evidence": [ { "id": "HGNC:20944", "url": "https://alliancegenome.org/gene/HGNC:20944#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZF42-1", "protein_name": "Sentrin-specific protease 7", "gene_name": "Senp7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDRARPGRRRASSEIVTEGKRKKSSPADLQKITKLLTVKSEDVLAQSPLPKLRGSECWWTRSLRNKVICLDHKTTKAAHGCPPKALPKRHLKVMLTNVLWTDLGREFRKTLPRNDAKLCDTSKVQSDSLPSTSVDSIETCQRLDPLHQSLNLSERIPRVILTDIRQTELGRKYLKIPSVTEASLSDTASPKSEELSSSADGSLESCQNVNHLKSFLSERGSKPSRTGDISAKEAANGRQEQGDDGDIAPEMVTPQSKDFNSGNKGDYHEEGTSNKNTSYSHSETDHTPVSRKRKKRGRSNFHNSHNPKSSVDKSTEYIKEEENESTVSSKLEESNEDSHQDPAPPEGLTPDSLETEATNVCSFVVQEPDVSAASGRACSPNKSSESSVSSEVAENSSAAEKGEASTVKEAPPPGGNSEENQLLMSAEPIVVSSDEEGPVEHKNSVILKLQPSQDYEFMSENQTTSDPQLSELMLGACESVQVSSELCPYNPDMENISCINPNSEMDLKLDFIFTCVYIGKIKGTSKGCITFTKKYIKIPFQVSMNEISLTVDTARLKRFGLWESKDDDHSKRSHAILFLWVSSNYLQDIQTQLENPMLSQQSKANEFIFLELNSPISQREELKLKDIMMEIGATNGELQLSCPLPWVQAFPLFQDLSPQEISFLHYYCASASSFPAVAGADMKKKPVSQPSNADVVKPTYTFLHKQSSGCYSLSITSSPDEEWREVRNTGPVQKLIVYPPPPTKGGLGVTNEDLECLEEGEFLNDVIIDFYLKYLLLEKASDELVERSHIFSSFFYKCLTRKENNLTEDNPDLSVAQRRHRRVRTWTRHINIFNKDYIFVPVNESSHWYLAVICFPWLEEAVYEDFPQTVSQEFQDQQSQHDNKTIDNDPHTTSTVFTSAEESQSTETSMSVPKKMCKRPCILILDSLKAASIQNTVQNLREYLEVEWEVKRKTHREFSKTNMVDLCPKVPKQDNSSDCGVYLLQYVESFFQDPIVNFELPIHLEKWFPRHVIKTKREDIRELILKLHLQQQKGSSS", "length": 1037 }, "evidence": [ { "id": "MGI:1913565", "url": "https://alliancegenome.org/gene/MGI:1913565#orthology", "database": "AGR" }, { "id": "HGNC:30402", "url": "https://alliancegenome.org/gene/HGNC:30402#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060531-45", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060531-45#orthology", "database": "AGR" }, { "id": "FB:FBgn0030420", "url": "https://alliancegenome.org/gene/FB:FBgn0030420#orthology", "database": "AGR" }, { "id": "RGD:1305510", "url": "https://alliancegenome.org/gene/RGD:1305510#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-345", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-345#orthology", "database": "AGR" }, { "id": "SGD:S000001293", "url": "https://alliancegenome.org/gene/SGD:S000001293#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LU78-1", "protein_name": "Sentrin-specific protease 6", "gene_name": "Senp6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAGKSGGSAGGVFLKALARSESKRDGGFKNNWSFDHEEESEGDADKDGANLLSVEDEDSETSKGKKLNRRSEIVATSSGDFILKTYVRRNKTDGFKTLKGNAIGLNMLSNNKKLSENTQATALCSGTVVHGRRFHHAHVQMPGIKTAAQSNQDRKERKEYPPHVHKAENNPVMLSHGQGGDHVMKKTEDSESYVEPEVKRKVQQKRHCSTYQLSPLSPASKKCLTHFEVSEQRECCPKCGKEKENQTRCQSCGIVFHNDLQRNCRQAVTLNESTGPLLRTSIHQNSGGQKSQNTGLTAKKFYGNSVDKIPIDILLTCDGSRHNYIQTNGKVILPGGKIPKITNPKERKTSVSDLNDPIILSSDDDDDDDRTKRRESTSPQPADSACSSPAPSTGKVEAALNANTCRAEQEPRSSPAESELNTVVIPRKARMKDQLGNSISTPLKRRKVNTHGALIPVTSLSCQDFGSVILNCRSIRVGTLFRLLVEPVIFSLELIKIRLDGPDSVEIILNTSDLTKCEWCNVRKLPVVFLQAIPAVYQKLSLQLQMSKEDKVWNDCKGINRITSLEEQYIILIFQTGLDHQADVVFESIITDIGIRNNVCNFFAKIPFEEANSRLVACTRSYEESIKGNCVQKENKVKTVSFESKIQLRSKQELQFFDDEEEAGESHTIFIGPVEKLIVYPPPPAKGGISVTNEDLHCLSEGEFLNDVIIDFYLKYLVLEKLKKEDADRIHIFSSFFYKRLNQRERRNSETTNLSIQQKRHGRVKTWTRHVDIFEKDFIFVPLNEAAHWFLAVVCFPGLEKPKYEPNPHYHENAVMQKPSRAEDSYVSSASEVDACSQNSAAKPVIKKMLHRKHCLAVTDSSAAQEDSEPCYRRNAYSVKCSMKKKNHAVHENEEPSNGESACQEISDRTESEHGLQDECLNSAHHPDALSKIRLNYGDQSAEGGKLLEDELIDFSEDQDDPDDSSDDGLLADENYNSEIGQWHLKPTVCKQPCILLMDSLRGPSRSNVVKILREYLEVEWEVKKGSKRSFSKDVMKGSNPKVPQQNNFSDCGVYVLQYVESFFENPILNFELPMNLVNWFPPPRMKTKREEIRNIILKLQEEQSKEKRLLRDTSSAETSLGEGAEQYASSVSE", "length": 1135 }, "evidence": [ { "id": "HGNC:20944", "url": "https://alliancegenome.org/gene/HGNC:20944#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080204-25", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080204-25#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P40537-1", "protein_name": "Ubiquitin-like-specific protease 2", "gene_name": "ULP2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSARKRKFNSLKPLDTLNSSRASSPRSSASLPPKRYNTFRKDPKIVDHLNNASTKDFLPVLSMNSESKRQIELSDNDVDNNDEGEGVNSGCSDQDFEPLQSSPLKRHSSLKSTSNGLLFQMSNNLGNGSPEPAVASTSPNGSIISTKLNLNGQFSCVDSKTLRIYRHKAPCIMTFVSDHNHPKFSLYFQQSVIYNSQVNLLDDVELIILDKKNSFMAIILKDLKKVKMILDVNNSSININTNILIWSTASSASNKKIKSIKRFLLMSYSSSIKVEILDHKEQILERLKHLIHPISSSSPSLNMERAINSTKNAFDSLRLKKTKLSTNDDESPQIHTHFLSNKPHGLQSLTKRTRIASLGKKEHSISVPKSNISPSDFYNTNGTETLQSHAVSQLRRSNRFKDVSDPANSNSNSEFDDATTEFETPELFKPSLCYKFNDGSSYTITNQDFKCLFNKDWVNDSILDFFTKFYIESSIEKSIIKREQVHLMSSFFYTKLISNPADYYSNVKKWVNNTDLFSKKYVVIPINISYHWFSCIITNLDAILDFHQNKDKNDAINSDEISINNPLVNILTFDSLRQTHSREIDPIKEFLISYALDKYSIQLDKTQIKMKTCPVPQQPNMSDCGVHVILNIRKFFENPVETIDVWKNSKIKSKHFTAKMINKYFDKNERNSARKNLRHTLKLLQLNYISYLKKENLYEEVMQMEEKKSTNINNNENYDDDDEEIQIIENIDQSSKDNNAQLTSEPPCSRSSSISTTEREPTELHNSVVRQPTGEIITDNEDPVRAASPETASVSPPIRHNILKSSSPFISESANETEQEEFTSPYFGRPSLKTRAKQFEGVSSPIKNDQALSSTHDIMMPSPKPKRIYPSKKIPQLSSHVQSLSTDSMERQSSPNNTNIVISDTEQDSRLGVNSESKNTSGIVNRDDSDVNLIGSSLPNVAEKNHDNTQESNGNNDSLGKILQNVDKELNEKLVDIDDVAFSSPTRGIPRTSATSKGSNAQLLSNYGDENNQSQDSVWDEGRDNPILLEDEDP", "length": 1034 }, "evidence": [ { "id": "MGI:1913565", "url": "https://alliancegenome.org/gene/MGI:1913565#orthology", "database": "AGR" }, { "id": "HGNC:30402", "url": "https://alliancegenome.org/gene/HGNC:30402#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060531-45", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060531-45#orthology", "database": "AGR" }, { "id": "FB:FBgn0030420", "url": "https://alliancegenome.org/gene/FB:FBgn0030420#orthology", "database": "AGR" }, { "id": "RGD:1305510", "url": "https://alliancegenome.org/gene/RGD:1305510#orthology", "database": "AGR" }, { "id": "SGD:S000001293", "url": "https://alliancegenome.org/gene/SGD:S000001293#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q6P7W0-1", "protein_name": "Sentrin-specific protease 6", "gene_name": "Senp6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAGKSGGSAGALFLKALDRSESKRDGGFKNNWSFDHEEESEGDADKDGANLLSVEDEDSEISKGKKLNRRSEIVATSSGDFILKTYVRRSKTDGFKTLKGNPIGLNMLSNNKKLSESTAGTALCSGTVVHGRRFHHAHSQTPGIRTAAQRKEYPPYVHKAENSPVMLSHGQGGDHIMKKTEESESYVESEIKRKVQQKRHCSTYQLSPLSPASKKCLTHLEVSEQREYCPKCGKEKENQTKCQSCGIVFHNDLQRNCRQAVTLNEPTGPLLRTSIHQNSGGQKSQNTGLTAKKFYGNSVDKIPIDILVTCDDSRHNYIQTNGKVILPGGKIPKLTNPKERKISVSDLNDPIILSSDDDDDDDDRTKRRESTSPKPADSACSSPVPSTGKVEAALNADACRAEQEPRSSPAEPELNTIVIPRKARMKDQLGNSISTPLKRRKVNSHAAFIHPMSLSCQNFESVILNCRSIRVGTLFRLLVEPVIFSLESITIHLDGPESDPVDIILNTSDLTKCEWCNVRKLPVVFLQAIPAVYQKLSMQLQMSKEDKVWNDCKGINRITSLEEQYIILIFQTGLDHQAEVVFESIITDIGIRNNVPNFFAKILFDEANSRLVACTRSYEESIKGNCAQKENKVKTVSFESKIQLRSKQELQFFDDDEEAGESHTIFIGPVEKLIVYPPPPAKGGISVTNEDLHCLSEGEFLNDVIIDFYLKYLVLEKLKKEDADRIHIFSSFFYKRLNQRERRNPETTNLSIQQKRHGRVKTWTRHVDIFEKDFIFVPLNEAAHWFLAVVCFPGLEKPKYEPNPHYHENAVMQKTPSAEDSCVSSASEMGACSQNSAAKPVIKKMLNRKHCLAVTDSSAAQEESEPCYRRNAYSVKCSMKKKNHAINENEEPSNGESTCQDICDRTQSENGLRDECFSSVHHPDALSKIRLNYGDQSADGGKLLEDELIDFSEDQDDPDDSSDDGLLADENYSSEIGQWHLKPTVCKQPCILLMDSLRGPSRSNVVKILREYLEVEWEVKKGSKRSFSKDVMKGSNPKVPQQNNFSDCGVYVLQYVESFFENPVLNFELPMNLMNWFPPPRMKTKREEIRNIILKLQESQSKDKKLLKDSLAETSLGDGAEQYASASGGSE", "length": 1132 }, "evidence": [ { "id": "HGNC:20944", "url": "https://alliancegenome.org/gene/HGNC:20944#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080204-25", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080204-25#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8BUH8-1", "protein_name": "Sentrin-specific protease 7", "gene_name": "Senp7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDRARPGRRRASSEIVTEGKRKKSSPADLQKITKLLTVKSEDVLAQSPLSKLRGSECWWTRSLRNKVICLDHKKPKAARGCPPKGLPKRHLRVMLTNVLWTDLGREFRKTLPRKDANLCAPSKVQSDSLPSTSVDSIETCQRLDPLHQSLNLSERTPRVILTDIRQTELGRKYLKIPPVTEASLSDTANLKSEQLSSSSDGSLESCQSVNHHKSFLSESGPKPSRTGDVPAKEAACGGQKQGDDGGVTPEMAAPHPKDFNTGNKGCDYLEEGTSNKNTSYSYSEMDHTPVSRKRKKRGRSNFHDSHNSKTSLDKPTEHTKEEENDSSVSRKLEESGEDSHQDPAPPEGLAPESLESEATNLRSFAAGQEPDASAASGRASSPNKSLESSASSEVSENSSVAVKGEALTLKEASPPGGSSEESQLLISAEPIVVSSDEEGPVEHKNSVILKLQPPHEIMSENQGTSDPQLSELTLGACESVQVTSELFPYNPDVENISCIKSNSEMDLKLDFIFTCVYIGKIKGTPKGCVTFTKKYIKIPFQVSTNEISLTVDTARLKRFGLWESKDEDHSKRSHAILFLWLSSDYLQDIQTQLENPMLSQQSKANEFIFLELNSSISQREELKLKDIMMEISTKNGNLHLSCPLPWVQALPLFQDLSPQEISFLHYYYASASALPTAAGADMKKKSVSQPSNSDTIKPTYTFLHKQSSGCYSLSITSSPEEEWQEVRNTGPVQKLIVYPPPPTKGGLGVTNEDLECLEEGEFLNDVIIDFYLKYLLLEKASDELVERSHIFSSFFYKCLTRKENNLTEDNPDLSVAQRRHRRVRTWTRHINIFNKDYIFVPVNESSHWYLAVICFPWLEEAVYEDCPQTVSQQFQGQQSQHDHKMTDNDPHTTSTVSTSAEDSQSTEVNMSVPKKMCKRPCILILDSLKAASIQNTVQNLREYLEVEWEVKRKTHREFSKTNMVDLCPKVPKQDNSSDCGVYLLQYVESFFQDPIVNFELPIHLEKWFPRHVIKTKREDIRELILKLHLQQQKGGSC", "length": 1037 }, "evidence": [ { "id": "MGI:1913565", "url": "https://alliancegenome.org/gene/MGI:1913565#orthology", "database": "AGR" }, { "id": "HGNC:30402", "url": "https://alliancegenome.org/gene/HGNC:30402#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060531-45", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060531-45#orthology", "database": "AGR" }, { "id": "FB:FBgn0030420", "url": "https://alliancegenome.org/gene/FB:FBgn0030420#orthology", "database": "AGR" }, { "id": "RGD:1305510", "url": "https://alliancegenome.org/gene/RGD:1305510#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-345", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-345#orthology", "database": "AGR" }, { "id": "SGD:S000001293", "url": "https://alliancegenome.org/gene/SGD:S000001293#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BQF6-1", "protein_name": "Sentrin-specific protease 7", "gene_name": "SENP7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDKRKLGRRPSSSEIITEGKRKKSSSDLSEIRKMLNAKPEDVHVQSPLSKFRSSERWTLPLQWERSLRNKVISLDHKNKKHIRGCPVTSKSSPERQLKVMLTNVLWTDLGRKFRKTLPRNDANLCDANKVQSDSLPSTSVDSLETCQKLEPLRQSLNLSERIPRVILTNVLGTELGRKYIRTPPVTEGSLSDTDNLQSEQLSSSSDGSLESYQNLNPHKSCYLSERGSQRSKTVDDNSAKQTAHNKEKRRKDDGISLLISDTQPEDLNSGSRGCDHLEQESRNKDVKYSDSKVELTLISRKTKRRLRNNLPDSQYCTSLDKSTEQTKKQEDDSTISTEFEKPSENYHQDPKLPEEITTKPTKSDFTKLSSLNSQELTLSNATKSASAGSTTETVENSNSIDIVGISSLVEKDENELNTIEKPILRGHNEGNQSLISAEPIVVSSDEEGPVEHKSSEILKLQSKQDRETTNENESTSESALLELPLITCESVQMSSELCPYNPVMENISSIMPSNEMDLQLDFIFTSVYIGKIKGASKGCVTITKKYIKIPFQVSLNEISLLVDTTHLKRFGLWKSKDDNHSKRSHAILFFWVSSDYLQEIQTQLEHSVLSQQSKSSEFIFLELHNPVSQREELKLKDIMTEISIISGELELSYPLSWVQAFPLFQNLSSKESSFIHYYCVSTCSFPAGVAVAEEMKLKSVSQPSNTDAAKPTYTFLQKQSSGCYSLSITSNPDEEWREVRHTGLVQKLIVYPPPPTKGGLGVTNEDLECLEEGEFLNDVIIDFYLKYLILEKASDELVERSHIFSSFFYKCLTRKENNLTEDNPNLSMAQRRHKRVRTWTRHINIFNKDYIFVPVNESSHWYLAVICFPWLEEAVYEDFPQTVSQQSQAQQSQNDNKTIDNDLRTTSTLSLSAEDSQSTESNMSVPKKMCKRPCILILDSLKAASVQNTVQNLREYLEVEWEVKLKTHRQFSKTNMVDLCPKVPKQDNSSDCGVYLLQYVESFFKDPIVNFELPIHLEKWFPRHVIKTKREDIRELILKLHLQQQKGSSS", "length": 1050 }, "evidence": [ { "id": "MGI:1913565", "url": "https://alliancegenome.org/gene/MGI:1913565#orthology", "database": "AGR" }, { "id": "HGNC:30402", "url": "https://alliancegenome.org/gene/HGNC:30402#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060531-45", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060531-45#orthology", "database": "AGR" }, { "id": "FB:FBgn0030420", "url": "https://alliancegenome.org/gene/FB:FBgn0030420#orthology", "database": "AGR" }, { "id": "RGD:1305510", "url": "https://alliancegenome.org/gene/RGD:1305510#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-345", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-345#orthology", "database": "AGR" }, { "id": "SGD:S000001293", "url": "https://alliancegenome.org/gene/SGD:S000001293#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9GZR1-1", "protein_name": "Sentrin-specific protease 6", "gene_name": "SENP6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAGKSGGSAGEITFLEALARSESKRDGGFKNNWSFDHEEESEGDTDKDGTNLLSVDEDEDSETSKGKKLNRRSEIVANSSGEFILKTYVRRNKSESFKTLKGNPIGLNMLSNNKKLSENTQNTSLCSGTVVHGRRFHHAHAQIPVVKTAAQSSLDRKERKEYPPHVQKVEINPVRLSRLQGVERIMKKTEESESQVEPEIKRKVQQKRHCSTYQPTPPLSPASKKCLTHLEDLQRNCRQAITLNESTGPLLRTSIHQNSGGQKSQNTGLTTKKFYGNNVEKVPIDIIVNCDDSKHTYLQTNGKVILPGAKIPKITNLKERKTSLSDLNDPIILSSDDDDDNDRTNRRESISPQPADSACSSPAPSTGKVEAALNENTCRAERELRSIPEDSELNTVTLPRKARMKDQFGNSIINTPLKRRKVFSQEPPDALALSCQSSFDSVILNCRSIRVGTLFRLLIEPVIFCLDFIKIQLDEPDHDPVEIILNTSDLTKCEWCNVRKLPVVFLQAIPAVYQKLSIQLQMNKEDKVWNDCKGVNKLTNLEEQYIILIFQNGLDPPANMVFESIINEIGIKNNISNFFAKIPFEEANGRLVACTRTYEESIKGSCGQKENKIKTVSFESKIQLRSKQEFQFFDEEEETGENHTIFIGPVEKLIVYPPPPAKGGISVTNEDLHCLNEGEFLNDVIIDFYLKYLVLEKLKKEDADRIHIFSSFFYKRLNQRERRNHETTNLSIQQKRHGRVKTWTRHVDIFEKDFIFVPLNEAAHWFLAVVCFPGLEKPKYEPNPHYHENAVIQKCSTVEDSCISSSASEMESCSQNSSAKPVIKKMLNKKHCIAVIDSNPGQEESDPRYKRNICSVKYSVKKINHTASENEEFNKGESTSQKVADRTKSENGLQNESLSSTHHTDGLSKIRLNYSDESPEAGKMLEDELVDFSEDQDNQDDSSDDGFLADDNCSSEIGQWHLKPTICKQPCILLMDSLRGPSRSNVVKILREYLEVEWEVKKGSKRSFSKDVMKGSNPKVPQQNNFSDCGVYVLQYVESFFENPILSFELPMNLANWFPPPRMRTKREEIRNIILKLQEDQSKEKRKHKDTYSTEAPLGEGTEQYVNSISD", "length": 1112 }, "evidence": [ { "id": "FB:FBgn0030420", "url": "https://alliancegenome.org/gene/FB:FBgn0030420#orthology", "database": "AGR" }, { "id": "HGNC:20944", "url": "https://alliancegenome.org/gene/HGNC:20944#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080204-25", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080204-25#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VRY4-1", "protein_name": "Veloren, isoform A", "gene_name": "velo", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEQYIVPLEEPVYSDLQVVQVPQDEVGSLVLQDDQQLVFNDQQQVVYQTTAPAQYQQPQQSAAPTYHIIGGDDLAHQQQQHQQQQQQQQQQQQQQQQPQQQHQQQQQQVVMHHQQHQVQQVQQVHYQQQQQEPQQQQQQLHMEQQQQQQQQYVQHQPQQPAIQHTQQIYYTSEQVLQPNAIVQHMQQQKKQQQVLQQQQQQQQQYQQHAPAYQVQSSPQGQAQLLQSSQQQHQQAQQAQTLQLQTSPPQQQPQQHQQIVYRMTTTQQQQRPLGMLNNTHVIVQQQPVLIQGPQHQELIMRQAIHPYNNRVVYATSPQQQQQQQHVIQQHVQQQQVQQHQQVQQQQQMQLQPTTQTAHLVQARVVPQQTQNVVYQQLQVQKVQPQQQQQAPQQQQPQLVAQQQPQLVATSAAGGTQLVRASFRKSPRGGAVLARPGTLITTRPTLTPTTIVRQVRPRGGAVPGGLVRNMRPAGVRPTRAQLVVQTSASGEGQTMLVTQGQMKHITISTNLGQPQQQQQQQMQQQPRHIYRTHMVTDGNPQQQQQQAAQQQPQQHQQMLMMRHGPVRYRAPVSSAVAAPVQAPAPTAAGGGVQTSNIGMDLEERIEAAVLKKEQQKPQPTAQPVASNQLQPMQIGTGTTLTTYYPAGTASQEEEQQQQQQQQQQQQQQQQQVVQSQQQGIRPPSGASMTLAEYKKRQTLSASPAPVPPSNPGLAPMRATPPGTMVRPTAKITPTQHAGALPPGTRIMQPQRPVPAAVAAPIPAPAAVTQGSSVMKTSHNNYEIHSQHVLNNRAGQEIAERDKNSAKMLVILASGEQRLITFTLPRESCTVQDLLEQVGVPFDHNTTIQCVEHRGANVDFVVTVGFTVHESASELISRAEESLQMNRSQENQAAVAGAAAAANSNPATTSASPAYAQANAAAEQAKREAASSASGNTVVGTVSSAGSAGATPSEGRKLIDGFLAVCQLCGFTGVDHARCERCKRVFPEPPKRKSYVPKNSAASSPASSSSSEPVSAVPTAADKKRELAAARFNNKMAGANFAVGVGVRGRGSMAMRGGRARGGRRVPEVDPVVLLSSEDEAEGGEGTSDSSNQPTNNSKLNSNGNLHELSAAFPCEPNLPEIDEEPLYKDFSRGDVRDLSDIPEADQFSASLKCSCVRLVPYRFEITEPVCFTTKGVRIAGILKDKDEKFELNIHKQEVIKVIAHFGNVEPAQPLVTLYLLKTCAEYVKNQLKLPDDQHHEHTGFKTHSYHTRRLILLFDSISVSARGNIKSMFSCVDEISSTDAAEILERIADSDRKTQDKSSQPPPRQLRADEQVSLLMYPPKGTGGLCIRMEDFVCLTKESYLNDIIIDFYLLWLRNTLIPEPQRERTHIFSTFFYKRLTTLTRPADMKQTAAQKRHARVQKWTKGVDIFDKDFIIVPINEQSHWFLAIICYPNLKGPVTFDTNQPVEPQQLKRPRGKKVALQIGNTTITPLTKRAEGGQLPAALTAENVCRIADDESERDEAEGDESDMASEDSENSNSAKEPAATPTSTTASTPSLSSSQPTATGPARNIASDDVPAVKQPLILIFDSLAGASRSRVVATLRDYLTCEYRVKKPDAQAHVFNKDNMPGHCVKVPQQNNFTDCGLYLLQYVEQFFGEPIRDYRLPIKQLTNWFDFLTVTKKREDIANLIQQLMDEGNQQQRLILPVIEFPTLNGQLVEYPEDTESAEFEEEEGHDDEDPASEMHDENNAGTDMEVDPVNEEPALAGKTAALAPASTTAAAPTGKRFVLKRRLHNGAVSSPTNGNGEASSNGGALIPQLVSTAAATTTGVSSGVAHLGPRGPSGGLKIRKIEP", "length": 1833 }, "evidence": [ { "id": "HGNC:30402", "url": "https://alliancegenome.org/gene/HGNC:30402#orthology", "database": "AGR" }, { "id": "HGNC:20944", "url": "https://alliancegenome.org/gene/HGNC:20944#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080204-25", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080204-25#orthology", "database": "AGR" }, { "id": "SGD:S000001293", "url": "https://alliancegenome.org/gene/SGD:S000001293#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "deSUMOylase activity", "id": "GO:0016929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016929", "evidence": [ { "database": "UniProtKB", "id": "Q9VYJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VYJ5" } ], "pmid": "" }, { "name": "SUMO-specific endopeptidase activity", "id": "GO:0070139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070139", "evidence": [ { "database": "UniProtKB", "id": "Q9VYJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VYJ5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VYJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VYJ5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VYJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VYJ5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9VYJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VYJ5" } ], "pmid": "" }, { "name": "central nervous system projection neuron axonogenesis", "id": "GO:0021952", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021952", "evidence": [ { "database": "UniProtKB", "id": "Q9VYJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VYJ5" } ], "pmid": "" }, { "name": "dendritic spine morphogenesis", "id": "GO:0060997", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060997", "evidence": [ { "database": "UniProtKB", "id": "Q9VYJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VYJ5" } ], "pmid": "" }, { "name": "protein desumoylation", "id": "GO:0016926", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016926", "evidence": [ { "database": "UniProtKB", "id": "Q9VYJ5", "url": "https://www.uniprot.org/uniprotkb/Q9VYJ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 237, "end_pos": 239, "annotation": "n_glycosylation_sequon" }, { "start_pos": 244, "end_pos": 246, "annotation": "n_glycosylation_sequon" }, { "start_pos": 367, "end_pos": 369, "annotation": "n_glycosylation_sequon" }, { "start_pos": 569, "end_pos": 571, "annotation": "n_glycosylation_sequon" }, { "start_pos": 624, "end_pos": 626, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VYJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VYJ5" }, { "id": "PS50600", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50600" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ubiquitin-like protease family profile", "eco_id": "ECO_0000259", "start_pos": 381, "end_pos": 584, "start_aa": "Leu", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 237, "end_pos": 239 }, { "start_pos": 244, "end_pos": 246 }, { "start_pos": 367, "end_pos": 369 }, { "start_pos": 569, "end_pos": 571 }, { "start_pos": 624, "end_pos": 626 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050861" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VYT1", "url": "https://www.uniprot.org/uniprotkb/Q9VYT1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "BORCS5", "url": "https://www.uniprot.org/uniprotkb/Q9VYT1", "locus": { "chromosome": "X", "start_pos": 11871299, "end_pos": 11872779, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0030346", "url": "https://www.ensemblgenomes.org/id/FBgn0030346" } ] } } ], "crossref": [ { "id": "FB:FBgn0030346", "url": "https://alliancegenome.org/gene/FB:FBgn0030346", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0030346", "url": 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"Q9VYT1", "url": "https://www.orthodb.org/?gene=Q9VYT1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31634", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31634", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31634:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31634:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10158", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10158", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_572759", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572759", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VYT1", "url": "https://www.uniprot.org/uniprotkb/Q9VYT1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VYT1-1", "url": "https://www.uniprot.org/uniprotkb/Q9VYT1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGAEHSQQRAEADGHEIFDGRQPPGAGTGSLGDGSSMMLAATAAANKRRGVGHRQQTTGGAGGTVVGPGAGVGPASIVIASKQIIAEAASPGGSELSRPPSPPLSVCSDLPYVSYTDRPIGDSPKIRSKPAHMLQQSSASRAAARKSHPSGLTSAVKPKRPQSTASSHNIVIVRPGAIDAGEDVDMDLARLRNIPQFLPVLRESITSATNTRDAEILERLNSQHLINICTRMQTHLNLCASYVASEQNHLVERTKVVSNSITTLFAGFVDMQKTYASYAEQFAKIRSISHQLSRCNSLLHENIASLEAINNFLDDEDRLEPFVWRTDDNKLRGEAEGAIGGNSSRLWRL", "length": 349, "header": "tr|Q9VYT1-1|Q9VYT1_DROME Isoform 1 of BLOC-1-related complex subunit 5 OS=Drosophila melanogaster OX=7227 GN=BORCS5 PE=3 SV=1 CANONICAL=Q9VYT1-1" }, "isoforms": [ { "isoform_ac": "Q9VYT1-1", "url": "https://www.uniprot.org/uniprotkb/Q9VYT1/entry#Q9VYT1-1", "sequence": { "sequence": "MGAEHSQQRAEADGHEIFDGRQPPGAGTGSLGDGSSMMLAATAAANKRRGVGHRQQTTGGAGGTVVGPGAGVGPASIVIASKQIIAEAASPGGSELSRPPSPPLSVCSDLPYVSYTDRPIGDSPKIRSKPAHMLQQSSASRAAARKSHPSGLTSAVKPKRPQSTASSHNIVIVRPGAIDAGEDVDMDLARLRNIPQFLPVLRESITSATNTRDAEILERLNSQHLINICTRMQTHLNLCASYVASEQNHLVERTKVVSNSITTLFAGFVDMQKTYASYAEQFAKIRSISHQLSRCNSLLHENIASLEAINNFLDDEDRLEPFVWRTDDNKLRGEAEGAIGGNSSRLWRL", "length": 349, "header": "tr|Q9VYT1-1|Q9VYT1_DROME Isoform 1 of BLOC-1-related complex subunit 5 OS=Drosophila melanogaster OX=7227 GN=BORCS5 PE=3 SV=1 CANONICAL=Q9VYT1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, 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J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VYT1", "url": "https://www.uniprot.org/uniprotkb/Q9VYT1" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VYT1", "url": "https://www.uniprot.org/uniprotkb/Q9VYT1" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VYT1", "url": "https://www.uniprot.org/uniprotkb/Q9VYT1" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VYT1", "url": "https://www.uniprot.org/uniprotkb/Q9VYT1" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VYT1", "url": "https://www.uniprot.org/uniprotkb/Q9VYT1" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VYT1", "url": "https://www.uniprot.org/uniprotkb/Q9VYT1" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VYT1", "url": "https://www.uniprot.org/uniprotkb/Q9VYT1" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VYT1", "url": "https://www.uniprot.org/uniprotkb/Q9VYT1" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VYT1", "url": "https://www.uniprot.org/uniprotkb/Q9VYT1" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VYT1", "url": "https://www.uniprot.org/uniprotkb/Q9VYT1" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VYT1", "url": "https://www.uniprot.org/uniprotkb/Q9VYT1" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], 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X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VYV6", "url": "https://www.uniprot.org/uniprotkb/Q9VYV6" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VYV6", "url": "https://www.uniprot.org/uniprotkb/Q9VYV6" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": 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JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VYZ8", "url": "https://www.uniprot.org/uniprotkb/Q9VYZ8" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VYZ8", "url": "https://www.uniprot.org/uniprotkb/Q9VYZ8" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VYZ8", "url": "https://www.uniprot.org/uniprotkb/Q9VYZ8" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VYZ8", "url": "https://www.uniprot.org/uniprotkb/Q9VYZ8" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VYZ8", "url": "https://www.uniprot.org/uniprotkb/Q9VYZ8" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VYZ8", "url": "https://www.uniprot.org/uniprotkb/Q9VYZ8" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VYZ8", "url": "https://www.uniprot.org/uniprotkb/Q9VYZ8" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VYZ8", "url": "https://www.uniprot.org/uniprotkb/Q9VYZ8" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VYZ8", "url": "https://www.uniprot.org/uniprotkb/Q9VYZ8" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VYZ8", "url": "https://www.uniprot.org/uniprotkb/Q9VYZ8" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VYZ8", "url": "https://www.uniprot.org/uniprotkb/Q9VYZ8" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG11750", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG11750", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E7F1D2-1", "protein_name": "PAXIP1-associated glutamate-rich protein 1", "gene_name": "pagr1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MQEAQDTLAERVESLGVGERDKTGEKEEQKEKDGDETSTAATHTPTEDNTAEGQKELREEQKEGTSTDGEVNGGEGQTQQQEVEEEEWMIPYSDEEMEEPQNWMPPPAEIKRLYELLAKGEELELQWVPLPRRPPTPPRTPSPEGDGDDTQDHTQEQAERKALTPTEFDFDEEQTLATPKNSFLTRRRTPGSSARSTVKREARLDKVLSDMKRHRKIEEQILRTGRDLFKSDKARAGPAIEKPLSPNSQREREKERERDSDPSTVFSPRQRRY", "length": 273 }, "evidence": [ { "id": "HGNC:28707", "url": "https://alliancegenome.org/gene/HGNC:28707#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5M865-1", "protein_name": "PAXIP1-associated glutamate-rich protein 1", "gene_name": "Pagr1", "tax_id": 10116, "organism": "Rattus 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"sequence": { "sequence": "MLKYLAGIFVSPRNDYANGRYRIPHPKKLAARRKSPPVNISTRSVINGGRSANGRLKTENRNARRRREGNPHLTRPHSRSSQKTIGIRLDPISYIVNVPNSTSSPDDDEEEVPVPQLPNAVNKLKARTYRKENSDCLIPPPVSRVASWSGPLNASPFNQLDEQNSISDDADAMGWKAICLPDDFWSEDSDSESKSKMSKINVF", "length": 203, "header": "tr|Q9VZ03-1|Q9VZ03_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=BcDNA:AT06648 PE=4 SV=1 CANONICAL=Q9VZ03-1" }, "isoforms": [ { "isoform_ac": "Q9VZ03-1", "url": "https://www.uniprot.org/uniprotkb/Q9VZ03/entry#Q9VZ03-1", "sequence": { "sequence": "MLKYLAGIFVSPRNDYANGRYRIPHPKKLAARRKSPPVNISTRSVINGGRSANGRLKTENRNARRRREGNPHLTRPHSRSSQKTIGIRLDPISYIVNVPNSTSSPDDDEEEVPVPQLPNAVNKLKARTYRKENSDCLIPPPVSRVASWSGPLNASPFNQLDEQNSISDDADAMGWKAICLPDDFWSEDSDSESKSKMSKINVF", "length": 203, "header": "tr|Q9VZ03-1|Q9VZ03_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=BcDNA:AT06648 PE=4 SV=1 CANONICAL=Q9VZ03-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ03", "url": "https://www.uniprot.org/uniprotkb/Q9VZ03" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ03", "url": "https://www.uniprot.org/uniprotkb/Q9VZ03" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ03", "url": "https://www.uniprot.org/uniprotkb/Q9VZ03" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ03", "url": "https://www.uniprot.org/uniprotkb/Q9VZ03" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ03", "url": "https://www.uniprot.org/uniprotkb/Q9VZ03" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ03", "url": "https://www.uniprot.org/uniprotkb/Q9VZ03" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ03", "url": "https://www.uniprot.org/uniprotkb/Q9VZ03" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ03", "url": "https://www.uniprot.org/uniprotkb/Q9VZ03" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ03", "url": "https://www.uniprot.org/uniprotkb/Q9VZ03" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VZ05-1", "uniprot_ac": "Q9VZ05", "uniprot_id": "Q9VZ05_DROME", "mass": { "chemical_mass": 37700.0, "monoisotopic_mass": 37700.0 }, "refseq": { "ac": "NP_001096954", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096954" }, "gene_names": [ { "name": "CG15197", "type": "recommended", "evidence": [ { "id": "Q9VZ05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ05" } ] }, { "name": "CG11757", "type": "synonym", "evidence": [ { "id": "NP_001096954", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096954" }, { "id": "Q9VZ05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ05" } ] }, { "name": "CG15197", "type": "synonym", "evidence": [ { "id": "NP_001096954", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096954" } ] }, { "name": "CG34348", "type": "synonym", "evidence": [ { "id": "NP_001096954", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096954" }, { "id": "Q9VZ05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ05" } ] }, { "name": "Dmel\\CG34348", "type": "synonym", "evidence": [ { "id": "NP_001096954", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096954" }, { "id": "Q9VZ05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ05" } ] }, { "name": "Dmel_CG34348", "type": "synonym", "evidence": [ { "id": "Q9VZ05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ05" } ] } ], "protein_names": [ { "name": "Phospholipid/glycerol acyltransferase domain-containing protein", "type": "recommended", "evidence": [ { "id": "Q9VZ05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ05/entry#names_and_taxonomy" } ] }, { "name": "CG34348-PA", "type": "synonym", "evidence": [ { "id": "NP_001096954", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096954" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_001096954", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096954" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VZ05", "url": "https://www.uniprot.org/uniprotkb/Q9VZ05" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "CG15197", "url": "https://www.uniprot.org/uniprotkb/Q9VZ05", "locus": { "chromosome": "X", "start_pos": 11344734, "end_pos": 11339873, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0085377", "url": "https://www.ensemblgenomes.org/id/FBgn0085377" } ] } } ], "crossref": [ { "id": "FB:FBgn0085377", "url": "https://alliancegenome.org/gene/FB:FBgn0085377", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0085377", "url": "https://bgee.org/?page=gene&gene_id=FBgn0085377", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07987", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07987", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0085377", "url": "https://flybase.org/reports/FBgn0085377", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "32072", "url": "https://www.ncbi.nlm.nih.gov/gene/32072", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002123", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002123", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG34348", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG34348", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SYWNGAR", "url": "https://omabrowser.org/oma/group/SYWNGAR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VZ05", "url": "https://www.orthodb.org/?gene=Q9VZ05", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22753", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22753", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22753:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22753:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01553", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01553", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001096954", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096954", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VZ05", "url": "https://www.uniprot.org/uniprotkb/Q9VZ05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VZ05-1", "url": "https://www.uniprot.org/uniprotkb/Q9VZ05-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEFLENLYKTLHSLLSSYIDLDYSLWLYRFLTPLIVTFLLPLVFVALIYISFLVLFIYKLHRQVIMRAVQGDRNFWRVGRKIVAAIWDAHARIYHGYEVIGLENVPQEGPALIVYYHGAIPIDMYYLNSRMLLQRERLIYTIGDRFLFKLPGWGTISEAFHVSPGTVQSCVSILRDGNLLAISPGGVYEAQFGDHYYELLWRNRVGFAKVAIEAKAPIIPCFTQNLREGFRQVGIFRTFFMRLYNKVRIPVYPIYGGFPVKFRTYLGKPIPYDENLTPQDLQIKVATAIEDLINQHQRLPGSILLALLDRLPTFRRRVRRKEE", "length": 323, "header": "tr|Q9VZ05-1|Q9VZ05_DROME Isoform 1 of Phospholipid/glycerol acyltransferase domain-containing protein OS=Drosophila melanogaster OX=7227 GN=CG15197 PE=1 SV=2 CANONICAL=Q9VZ05-1" }, "isoforms": [ { "isoform_ac": "Q9VZ05-1", "url": "https://www.uniprot.org/uniprotkb/Q9VZ05/entry#Q9VZ05-1", "sequence": { "sequence": "MEFLENLYKTLHSLLSSYIDLDYSLWLYRFLTPLIVTFLLPLVFVALIYISFLVLFIYKLHRQVIMRAVQGDRNFWRVGRKIVAAIWDAHARIYHGYEVIGLENVPQEGPALIVYYHGAIPIDMYYLNSRMLLQRERLIYTIGDRFLFKLPGWGTISEAFHVSPGTVQSCVSILRDGNLLAISPGGVYEAQFGDHYYELLWRNRVGFAKVAIEAKAPIIPCFTQNLREGFRQVGIFRTFFMRLYNKVRIPVYPIYGGFPVKFRTYLGKPIPYDENLTPQDLQIKVATAIEDLINQHQRLPGSILLALLDRLPTFRRRVRRKEE", "length": 323, "header": "tr|Q9VZ05-1|Q9VZ05_DROME Isoform 1 of Phospholipid/glycerol acyltransferase domain-containing protein OS=Drosophila melanogaster OX=7227 GN=CG15197 PE=1 SV=2 CANONICAL=Q9VZ05-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ05", "url": "https://www.uniprot.org/uniprotkb/Q9VZ05" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ05", "url": "https://www.uniprot.org/uniprotkb/Q9VZ05" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ05", "url": "https://www.uniprot.org/uniprotkb/Q9VZ05" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ05", "url": "https://www.uniprot.org/uniprotkb/Q9VZ05" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ05", "url": "https://www.uniprot.org/uniprotkb/Q9VZ05" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ05", "url": "https://www.uniprot.org/uniprotkb/Q9VZ05" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ05", "url": "https://www.uniprot.org/uniprotkb/Q9VZ05" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ05", "url": "https://www.uniprot.org/uniprotkb/Q9VZ05" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ05", "url": "https://www.uniprot.org/uniprotkb/Q9VZ05" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ05", "url": "https://www.uniprot.org/uniprotkb/Q9VZ05" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ05", "url": "https://www.uniprot.org/uniprotkb/Q9VZ05" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG34348", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG34348", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PUT3-1", "protein_name": "Transmembrane protein 68", "gene_name": "TMEM68", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MIGSNESSTEGPIPTSYLSFLAYLLGEWTGVEHTEDYLSYGAYLSWVLFPLAIVFILPVAIFFFCFNTSLLLLHIYKRRKNGFNEGHSGDVWYGAKEMLANLWDGHGRVWHGYELHGDENIPEGPALIVFYHGASPVDYLYFMARLLIRRKRYCHVVADHFVFRLPGLKMFIEVLGVMHGPKEVCVSALKKGYLLAISPGGVREALFSDETYAIMWGNRKGFAQVAIDAKVPIIPMFTQNVREGIRTLGGIKIFRKLYERIRLPIVPMYGWFPVKFRTFIGEPIPYDPNITAEELTAKTKAALQALITKHQKIPGNILRALMERFQTRQKED", "length": 332 }, "evidence": [ { "id": "Q9VZ05", "url": "https://omabrowser.org/oma/group/Q9VZ05/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A3L7IAZ3-1", "protein_name": "Transmembrane protein 68 isoform X1", "gene_name": "Tmem68", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLDNNQTCTVGQDCVPYMTCVVHMLEEWLGVEQLEDYLNFANYLLWVFTPLLLLILPYFTIFLLYITIIFLHIYKRKNVLKEAYSHNLWDGARKTVATLWDGHAAVWHGYEVHGMEKIPEGPALIIFYHGAIPIDFYYFMAKIFIHKGRACRVVADHFVFKIPGFSLLLDVFCALHGPREKCVEILRSGHLLAISPGGVREALLSDETYNIIWGNRKGFAQVAIDAKVPIIPMFTQNIREGFRSLGGTRLFKWLYEKFRYPFAPLYGGFPVKLRTYLGDPIPYDPKITAEELAEKTKNALQALIDKHQRIPGNIRSALLDRFHRGQQAN", "length": 329 }, "evidence": [ { "id": "Q9VZ05", "url": "https://omabrowser.org/oma/group/Q9VZ05/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8D1WF85-1", "protein_name": "Transmembrane protein 68", "gene_name": "TMEM68", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MIGKNQTCGTGQDSMPYMTCLVHILEGWFGVEQLEDYLNFANYLLWVFTPLILLILPYFTIFLLYLTIIFLHIYKRKNVLREAYSHNLWDGARKTVATLWDGHAAVWHGYEVHGMEKIPEEGPALIIFYHGAIPIDFYYFMAKIFIHKGRTCRVVADHFVFKIPGFSLLLDVFCALHGPREKCVEILRSGHLLAISPGGVREALLSDETYNIVWGNRKGFAQVAIDAKVPIIPMFTQNIREGFRSLGGTRLFRWLYEKFRYPFAPMYGGFPVKLRTYLGDPIPYDPKITAEELAEKTKDAVQALIDKHQRIPGNIMSALLERFHKKQKIN", "length": 330 }, "evidence": [ { "id": "Q9VZ05", "url": "https://omabrowser.org/oma/group/Q9VZ05/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZF19-1", "protein_name": "Transmembrane protein 68", "gene_name": "Tmem68", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MINNNQTCAAGQDSVPYVTCMLHVLEEWLGVEQLEDYLNFANHLLWVFTPLILLILPYFTIFLLYLTIIFLHIYKRKNVLKEAYSHNLWDGARKTVATLWDGHAAVWHGYEVHGMEKIPEGPALIIFYHGAIPIDFYYFMAKIFIHKGRTCRVVADHFVFKIPGFSLLLDVFCALHGPREKCVEILRSGHLLAISPGGVREALLSDETYNIIWGNRKGFAQVAIDAKVPIIPMFTQNIREGFRSLGGTRLFKWLYEKFRYPFAPMYGGFPVKLRTFLGDPIPYDPEVTAEELAEKTKNAVQALIDKHQRIPGNIRSALLDRFHKEQKAN", "length": 329 }, "evidence": [ { "id": "HGNC:26510", "url": "https://alliancegenome.org/gene/HGNC:26510#orthology", "database": "AGR" }, { "id": "RGD:1309006", "url": "https://alliancegenome.org/gene/RGD:1309006#orthology", "database": "AGR" }, { "id": "MGI:1919348", "url": "https://alliancegenome.org/gene/MGI:1919348#orthology", "database": "AGR" }, { "id": "FB:FBgn0085377", "url": "https://alliancegenome.org/gene/FB:FBgn0085377#orthology", "database": "AGR" }, { "id": "Q9VZ05", "url": "https://omabrowser.org/oma/group/Q9VZ05/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q0VCR6-1", "protein_name": "DGAT1/2-independent enzyme synthesizing storage lipids", "gene_name": "TMEM68", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTNKNQSFGVGQDSMSSMTCLIHVLEAWFGVEHLEDYWNFANYLLWVFTPLLLLILPYFTIFLLYLTIIFLHIYKRKNVLKEAYSHNLWDGARKTVATLWDGHAAVWHGYEVHGMEKIPEEGPALIIFYHGAIPIDFYYFMAKIFIHKGRTCRVVADHFVFKIPGFSLLLDVFCAIHGPREKCVEILQSGHLLAISPGGVREALMSDETYNIVWGNRKGFAQVAIDAKVPIIPMFTQNIREGFRSLGGTRLFRWLYEKFRYPFAPMYGGFPVKLRTYLGDPIPYDPKITAEELAEKTKDAVQALIDKHQRIPGNIMSALLERFRNKQKINQKTL", "length": 334 }, "evidence": [ { "id": "Q9VZ05", "url": "https://omabrowser.org/oma/group/Q9VZ05/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q96MH6-1", "protein_name": "DGAT1/2-independent enzyme synthesizing storage lipids", "gene_name": "TMEM68", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MIDKNQTCGVGQDSVPYMICLIHILEEWFGVEQLEDYLNFANYLLWVFTPLILLILPYFTIFLLYLTIIFLHIYKRKNVLKEAYSHNLWDGARKTVATLWDGHAAVWHGYEVHGMEKIPEDGPALIIFYHGAIPIDFYYFMAKIFIHKGRTCRVVADHFVFKIPGFSLLLDVFCALHGPREKCVEILRSGHLLAISPGGVREALISDETYNIVWGHRRGFAQVAIDAKVPIIPMFTQNIREGFRSLGGTRLFRWLYEKFRYPFAPMYGGFPVKLRTYLGDPIPYDPQITAEELAEKTKNAVQALIDKHQRIPGNIMSALLERFH", "length": 324 }, "evidence": [ { "id": "HGNC:26510", "url": "https://alliancegenome.org/gene/HGNC:26510#orthology", "database": "AGR" }, { "id": "RGD:1309006", "url": "https://alliancegenome.org/gene/RGD:1309006#orthology", "database": "AGR" }, { "id": "MGI:1919348", "url": "https://alliancegenome.org/gene/MGI:1919348#orthology", "database": "AGR" }, { "id": "FB:FBgn0085377", "url": "https://alliancegenome.org/gene/FB:FBgn0085377#orthology", "database": "AGR" }, { "id": "Q9VZ05", "url": "https://omabrowser.org/oma/group/Q9VZ05/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D850-1", "protein_name": "DGAT1/2-independent enzyme synthesizing storage lipids", "gene_name": "Tmem68", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIDNNQTCAAGQDSVPYVTCMIYVLEEWLGVEQLEDYLNFANHLLWVFTPLILLILPYFTIFLLYLTIIFLHIYKRKNVLKEAYSHNLWDGARKTVATLWDGHAAVWHGYEVHGMEKIPEGAALIIFYHGAIPIDFYYFMAKIFIQKGRTCRVVADHFVFKIPGFSLLLDVFCALHGPREKCVEILRSGHLLAISPGGVREALLSDETYNIIWGNRKGFAQVAIDAKVPIIPMFTQNIREGFRSLGGTRLFKWLYEKFRYPFAPMYGGFPVKLRTFLGDPIPYDPKVTAEELAEKTKNAVQALIDKHQRIPGNIRSALLDRFHKEQKAH", "length": 329 }, "evidence": [ { "id": "HGNC:26510", "url": "https://alliancegenome.org/gene/HGNC:26510#orthology", "database": "AGR" }, { "id": "RGD:1309006", "url": "https://alliancegenome.org/gene/RGD:1309006#orthology", "database": "AGR" }, { "id": "MGI:1919348", "url": "https://alliancegenome.org/gene/MGI:1919348#orthology", "database": "AGR" }, { "id": "FB:FBgn0085377", "url": "https://alliancegenome.org/gene/FB:FBgn0085377#orthology", "database": "AGR" }, { "id": "Q9VZ05", "url": 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"sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VZ26-1", "uniprot_ac": "Q9VZ26", "uniprot_id": "Q9VZ26_DROME", "mass": { "chemical_mass": 13034.0, "monoisotopic_mass": 13034.0 }, "refseq": { "ac": "NP_001245617", "name": "uncharacterized protein, isoform B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245617" }, "gene_names": [ { "name": "DIGF-3", "type": "recommended", "evidence": [ { "id": "Q9VZ26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ26" } ] }, { "name": "CG15199", "type": "synonym", "evidence": [ { "id": "NP_001245617", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245617" }, { "id": "Q9VZ26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ26" } ] }, { "name": "DIGF-3", "type": "synonym", "evidence": [ { "id": "NP_001245617", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245617" } ] }, { "name": "Dmel\\CG15199", "type": "synonym", "evidence": [ { "id": "NP_001245617", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245617" }, { "id": "Q9VZ26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ26" } ] }, { "name": "Dmel_CG15199", "type": "synonym", "evidence": [ { "id": "Q9VZ26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ26" } ] } ], "protein_names": [ { "name": "Single domain-containing protein", "type": "recommended", "evidence": [ { "id": "Q9VZ26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ26/entry#names_and_taxonomy" } ] }, { "name": "CG15199-PB", "type": "synonym", "evidence": [ { "id": "NP_001245617", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245617" } ] }, { "name": "uncharacterized protein, isoform B", "type": "synonym", "evidence": [ { "id": "NP_001245617", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245617" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VZ26", "url": "https://www.uniprot.org/uniprotkb/Q9VZ26" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "DIGF-3", "url": "https://www.uniprot.org/uniprotkb/Q9VZ26", "locus": { "chromosome": "X", "start_pos": 11140474, "end_pos": 11141835, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0030270", "url": "https://www.ensemblgenomes.org/id/FBgn0030270" } ] } } ], "crossref": [ { "id": "FB:FBgn0030270", "url": "https://alliancegenome.org/gene/FB:FBgn0030270", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0030270", "url": "https://bgee.org/?page=gene&gene_id=FBgn0030270", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0030270", "url": "https://flybase.org/reports/FBgn0030270", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "32051", "url": "https://www.ncbi.nlm.nih.gov/gene/32051", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029277", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029277", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053308", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053308", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG15199", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG15199", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TQYRGNT", "url": "https://omabrowser.org/oma/group/TQYRGNT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VZ26", "url": "https://www.orthodb.org/?gene=Q9VZ26", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR39957", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR39957", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR39957:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR39957:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15430", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15430", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001245617", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245617", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VZ26", "url": "https://www.uniprot.org/uniprotkb/Q9VZ26", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VZ26-1", "url": "https://www.uniprot.org/uniprotkb/Q9VZ26-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGAAWMSLAFVACLLAASVDGNGFSTQYRGHTQHPSLAEHCLYEELDLAVPLNGYVLPSGQQGYCIRLECTDDYLLLIRHCDKQPWPRPGCHLSPNDYDFKFPECCPQLECSDEY", "length": 116, "header": "tr|Q9VZ26-1|Q9VZ26_DROME Isoform 1 of Single domain-containing protein OS=Drosophila melanogaster OX=7227 GN=DIGF-3 PE=4 SV=1 CANONICAL=Q9VZ26-1" }, "isoforms": [ { "isoform_ac": "Q9VZ26-1", "url": "https://www.uniprot.org/uniprotkb/Q9VZ26/entry#Q9VZ26-1", "sequence": { "sequence": "MSGAAWMSLAFVACLLAASVDGNGFSTQYRGHTQHPSLAEHCLYEELDLAVPLNGYVLPSGQQGYCIRLECTDDYLLLIRHCDKQPWPRPGCHLSPNDYDFKFPECCPQLECSDEY", "length": 116, "header": "tr|Q9VZ26-1|Q9VZ26_DROME Isoform 1 of Single domain-containing protein OS=Drosophila melanogaster OX=7227 GN=DIGF-3 PE=4 SV=1 CANONICAL=Q9VZ26-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ26", "url": "https://www.uniprot.org/uniprotkb/Q9VZ26" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ26", "url": "https://www.uniprot.org/uniprotkb/Q9VZ26" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ26", "url": "https://www.uniprot.org/uniprotkb/Q9VZ26" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ26", "url": "https://www.uniprot.org/uniprotkb/Q9VZ26" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ26", "url": "https://www.uniprot.org/uniprotkb/Q9VZ26" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. 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Common clinical signs and symptoms include delusions, hallucinations, disorganized thinking, and retreat from reality." }, { "id": "MONDO:0005090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005090", "name": "schizophrenia 12", "description": "" }, { "id": "MONDO:0005090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005090", "name": "schizophrenia", "description": "" }, { "id": "MONDO:0005090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005090", "name": "schizophrenia (disease)", "description": "" }, { "id": "MONDO:0005090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005090", "name": "SCZD", "description": "" }, { "id": "MIM:181500", "resource": "MIM", "url": "https://www.omim.org/entry/181500", "name": "Schizophrenia", "description": "Schizophrenia" } ], "unlinked_id_list": [], "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ] }, { "disease_id": "DOID:7148", "recommended_name": { "id": "DOID:7148", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:7148", "name": "rheumatoid arthritis", "description": "An arthritis that is an autoimmune disease which attacks healthy cells and tissue located_in joint." }, "synonyms": [ { "id": "DOID:7148", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:7148", "name": "Arthritis or polyarthritis, rheumatic", "description": "" }, { "id": "DOID:7148", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:7148", "name": "atrophic Arthritis", "description": "" }, { "id": "MONDO:0008383", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008383", "name": "rheumatoid arthritis", "description": "A chronic, systemic autoimmune disorder characterized by inflammation in the synovial membranes and articular surfaces. It manifests primarily as a symmetric, erosive polyarthritis that spares the axial skeleton and is typically associated with the presence in the serum of rheumatoid factor." }, { "id": "MONDO:0008383", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008383", "name": "RA", "description": "" }, { "id": "MONDO:0008383", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008383", "name": "rheumatoid arthritis", "description": "" }, { "id": "MIM:180300", "resource": "MIM", "url": "https://www.omim.org/entry/180300", "name": "Rheumatoid arthritis", "description": "Rheumatoid arthritis" } ], "unlinked_id_list": [], "evidence": [ { "id": "7148", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7148" } ] }, { "disease_id": "DOID:9744", "recommended_name": { "id": "DOID:9744", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9744", "name": "type 1 diabetes mellitus", "description": "A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production." }, "synonyms": [ { "id": "DOID:9744", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9744", "name": "IDDM", "description": "" }, { "id": "DOID:9744", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9744", "name": "insulin-dependent diabetes mellitus", "description": "" }, { "id": "DOID:9744", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9744", "name": "type I diabetes mellitus", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "type 1 diabetes mellitus", "description": "A chronic condition characterized by minimal or absent production of insulin by the pancreas." }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "IDDM", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "T1D", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "T1DM", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "diabetes mellitis type 1", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "diabetes mellitis type I", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "immune mediated diabetes", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "insulin dependent diabetes", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "juvenile diabetes", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "type 1 diabetes", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "type I diabetes", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "type I diabetes mellitus", "description": "" }, { "id": "MIM:222100", "resource": "MIM", "url": "https://www.omim.org/entry/222100", "name": "Type 1 diabetes mellitus", "description": "Type 1 diabetes mellitus" } ], "unlinked_id_list": [], "evidence": [ { "id": "9744", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9744" } ] }, { "disease_id": "DOID:986", "recommended_name": { "id": "DOID:986", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:986", "name": "alopecia areata", "description": "An autoimmune disease resulting in the loss of hair on the scalp and elsewhere on the body initially causing bald spots." }, "synonyms": [ { "id": "DOID:986", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:986", "name": "Circumscribed alopecia", "description": "" }, { "id": "MONDO:0007082", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007082", "name": "alopecia areata 1", "description": "" }, { "id": "MONDO:0007082", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007082", "name": "alopecia areata 1", "description": "" }, { "id": "MONDO:0007082", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007082", "name": "AA1", "description": "" }, { "id": "MONDO:0012551", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012551", "name": "alopecia areata 2", "description": "" }, { "id": "MONDO:0012551", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012551", "name": "AA2", "description": "" }, { "id": "MONDO:0012551", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012551", "name": "alopecia areata 2", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "986", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:986" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VZ44", "url": "https://www.uniprot.org/uniprotkb/Q9VZ44" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "C901", "url": "https://www.uniprot.org/uniprotkb/Q9VZ44", "locus": { "chromosome": "X", "start_pos": 10964032, "end_pos": 10967134, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0021742", "url": "https://www.ensemblgenomes.org/id/FBgn0021742" } ] } } ], "crossref": [ { "id": "FB:FBgn0021742", "url": "https://alliancegenome.org/gene/FB:FBgn0021742", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0021742", "url": "https://bgee.org/?page=gene&gene_id=FBgn0021742", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0021742", "url": "https://flybase.org/reports/FBgn0021742", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "32032", "url": "https://www.ncbi.nlm.nih.gov/gene/32032", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001774", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001774", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002049", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002049", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG1567", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG1567", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PETCENE", "url": "https://omabrowser.org/oma/group/PETCENE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VZ44", "url": "https://www.orthodb.org/?gene=Q9VZ44", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14949", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14949", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14949:SF57", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14949:SF57", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00008", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00008", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00053", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00053", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01414", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01414", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21700", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21700", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-2979096", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-2979096", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_572673", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572673", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VZ44", "url": "https://www.uniprot.org/uniprotkb/Q9VZ44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VZ44-1", "url": "https://www.uniprot.org/uniprotkb/Q9VZ44-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLSDKKAALLLVTAITALKLEEMNAYRRNFDARQSSNSNIPLWKQRACEKSQKQRQNAHYVCDEKGDFKCLPGWQGDLCQVPMCRRGCDPMNGYCQRPGECRCRIGYSGELCDKCIPLPGCQHGGCTKPFECICKPGWAGLFCTEPSCRTGCHSTRGYCEAPGECRCRIGYAGRTCSECATMPGCQHGTCNKPLECLCLPGYTGLLCQTPICDPDCSKQHGYCRKPGECRCKVGWTGSQCDKCFPYPGCANGDCEAPWECNCHPGWGGMLCDEKLTYCVEHPDTCENGGKCTSLSREDGSYQCQCRQGFLGKNCEIRDDFLLTSEAPPRITPPTPAELVLELDGELDQNGQQDIGAGVPDDSEPGGGLVGEKLPAGNEPERRKNDTVANVATAGTGAGAGPMNSLPGNSNATRTTLVVATETGSDNATNEALSAVTTRRATPIPLTSGEKTVKGNATSVSVATGPQPRPPLPIVASQEQTIANLAPAGTVTVTATTAPTATTAATSVTSHKDKPNVADEEEDEDDDDDEEDEDGEYDEEEDEDEDDEEDDSDQLIPNII", "length": 559, "header": "tr|Q9VZ44-1|Q9VZ44_DROME Isoform 1 of Delta-like protein OS=Drosophila melanogaster OX=7227 GN=C901 PE=4 SV=1 CANONICAL=Q9VZ44-1" }, "isoforms": [ { "isoform_ac": "Q9VZ44-1", "url": "https://www.uniprot.org/uniprotkb/Q9VZ44/entry#Q9VZ44-1", "sequence": { "sequence": "MLSDKKAALLLVTAITALKLEEMNAYRRNFDARQSSNSNIPLWKQRACEKSQKQRQNAHYVCDEKGDFKCLPGWQGDLCQVPMCRRGCDPMNGYCQRPGECRCRIGYSGELCDKCIPLPGCQHGGCTKPFECICKPGWAGLFCTEPSCRTGCHSTRGYCEAPGECRCRIGYAGRTCSECATMPGCQHGTCNKPLECLCLPGYTGLLCQTPICDPDCSKQHGYCRKPGECRCKVGWTGSQCDKCFPYPGCANGDCEAPWECNCHPGWGGMLCDEKLTYCVEHPDTCENGGKCTSLSREDGSYQCQCRQGFLGKNCEIRDDFLLTSEAPPRITPPTPAELVLELDGELDQNGQQDIGAGVPDDSEPGGGLVGEKLPAGNEPERRKNDTVANVATAGTGAGAGPMNSLPGNSNATRTTLVVATETGSDNATNEALSAVTTRRATPIPLTSGEKTVKGNATSVSVATGPQPRPPLPIVASQEQTIANLAPAGTVTVTATTAPTATTAATSVTSHKDKPNVADEEEDEDDDDDEEDEDGEYDEEEDEDEDDEEDDSDQLIPNII", "length": 559, "header": "tr|Q9VZ44-1|Q9VZ44_DROME Isoform 1 of Delta-like protein OS=Drosophila melanogaster OX=7227 GN=C901 PE=4 SV=1 CANONICAL=Q9VZ44-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 334, "start_aa": "Thr", "end_pos": 334, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr334", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ44", "url": "https://www.uniprot.org/uniprotkb/Q9VZ44" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ44", "url": "https://www.uniprot.org/uniprotkb/Q9VZ44" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ44", "url": "https://www.uniprot.org/uniprotkb/Q9VZ44" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ44", "url": "https://www.uniprot.org/uniprotkb/Q9VZ44" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ44", "url": "https://www.uniprot.org/uniprotkb/Q9VZ44" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ44", "url": "https://www.uniprot.org/uniprotkb/Q9VZ44" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ44", "url": "https://www.uniprot.org/uniprotkb/Q9VZ44" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ44", "url": "https://www.uniprot.org/uniprotkb/Q9VZ44" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ44", "url": "https://www.uniprot.org/uniprotkb/Q9VZ44" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ44", "url": "https://www.uniprot.org/uniprotkb/Q9VZ44" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ44", "url": "https://www.uniprot.org/uniprotkb/Q9VZ44" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG1567", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG1567", "resource": "KEGG Pathway" }, { "id": "R-DME-2979096", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-2979096", "resource": "Reactome", "description": "NOTCH2 Activation and Transmission of Signal to the Nucleus" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K8C1-1", "protein_name": "Nephronectin", "gene_name": "Npnt", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVLLVAVLASSLYLQVAADFDGRWPRQIVSSIGLCRYGGRIDCCWGWARQSWGQCQPFYVLRQRLARIRCQLKAVCQPQCKHGECVGPNKCKCHPGFAGKTCNQDEPFHPTPLDQGSEQPLFQPPDHQATSVPSRDLNECGLKPRPCKHRCMNTFGSYKCYCLNGYMLMPDGSCSSALSCSMANCQYGCDVIKGQIRCQCPSPGLQLAPDGRTCVDIDECATGRVSCPRFRQCVNTFGSYICKCHTGFDLMYIGGKYQCHDIDECSLGQHQCSSYARCYNIHGSYKCQCKDGYEGDGLNSFPQEIRGSIKAITKEDEGHKRNGTILKGDGGYANRIPDAGSTRWPLKTPYIPPPVITNRPTSKPTARPTPNPTPQPTPPPPPPLPTELRTTPLPPTPERPATSPTTVAPATQVVTVDNRIQTDPQKPRGDVFIPRQPSNDLFEIFEIERGVSADEEAKDDPGILIHSCNFDHGLCGWIREKDSDLHWEPTRDPAGGQYLTVSAAKAPGGKAARLVLPLGHLMHSGDLCLSFRHKVTGLHSGALQVFVRKHGTHGSALWGRNGGHGWRQTQITLRGADVKSVIFKGEKRRGHTGEIGLDDVSLKRGRC", "length": 608 }, "evidence": [ { "id": "Q9VZ44", "url": "https://omabrowser.org/oma/group/Q9VZ44/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A3Q1N3A9-1", "protein_name": "Nephronectin", "gene_name": "NPNT", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDFLLALLLGSSLYLQAAAEFDGRWPRQIVSSIGLCRYGGRIDCCWGWARRPWGQCQPVCQPQCKHGECVGPNKCKCHPGFAGKTCNQDEHLYPTPLDQGSEQPLLQPPDHPATSLPSRDLNECGLKPRPCKHRCMNTFGSYKCYCLSGYMLLPDGSCSSALTCSMANCQYGCDVVKGQIRCKCPSPGLQLAPDGRTCVDIDECATGRASCPRHRQCVNTFGSYICKCHKGFDLMYIGGKYQCHDIDECSLGQYQCSSFARCYNIHGSYKCKCKDGYQGDGLNCVYIPRVMIEPSGPIHVPKGNGTISKGDGGHGNWIPDVRSTRWPLKTPYMPPVMIDRPTSKPTARPTPKPIPEPTPPPPPPTELRTPPPATAPERPTTRLTTVAPVATTSPREITVDNKIQTDTQKPRGDVFSVLIHSCNFDHGLCGWIREKDSDVHWEPVRDPAGGQYLTVSAAKGPLGRAARLLLPLGHLLHAGDLCLSFRHKVTGLHSGTLQVLVRKHGAHGAALWGRNGGHGWRQTHITLRGADIKSVIFKGEKRHGHTGEIGLDDVSLKKGHCSEEREQLQN", "length": 570 }, "evidence": [ { "id": "Q9VZ44", "url": "https://omabrowser.org/oma/group/Q9VZ44/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8V0XPI7-1", "protein_name": "Nephronectin", "gene_name": "NPNT", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MELSVRLLLASCLSLGAAGEFDRRWPRQIVSSAGLCRYGSRIDCCWGWARLAWRQCQPFYVLRQRIASLRCQPKAICQPGCKHGECIGPNKCKCHPGYTGKTCNQDEQLYSSRPGQNSEAHLFRPLEHHSRNTPSRDLNECGLKPRPCKHRCMNTYGSYKCYCLNGYMLLPDGTCSSTARLGALSCSMANCQYGCDVLKGEVRCRCPSPGLQLGPDGRTCIDIDECATGRVICPRFRHCVNTFGSYMCRCHKGFDLMYIGGKYQCHDIDECSLGQHQCGSFSRCYNTPGSYKCKCKEGYRDNGTNCIQRPVTRPTARPTPGPTTRTTLRPTTRPTPKPTTRYVPVTTRPVTKPVTKPPPPTPPLPTTVRPTLPPQRIPLITTTHPLLVPDETTSSQGATDDNRIQIDPQKPRGDVFIPRQPGVSNNLFEILEIERGITADEFEANDDPGTLVHSCNFDSGLCGWIKDKDDGLHWEPVRDVSGGRYLTISEPKGTEGKAAHLILPLGHVAQAGDLCLSFRHKVPGLHSGALQVFVRRSGAHGPAVWGRNGGHGWRQTHITLRGLGIKSVIFKGEKGEGRTGDIGLDDVMLRRGRCSEEH", "length": 598 }, "evidence": [ { "id": "Q9VZ44", "url": "https://omabrowser.org/oma/group/Q9VZ44/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P31695-1", "protein_name": "Neurogenic locus notch homolog protein 4", "gene_name": "Notch4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQPQLLLLLLLPLNFPVILTRELLCGGSPEPCANGGTCLRLSRGQGICQCAPGFLGETCQFPDPCRDTQLCKNGGSCQALLPTPPSSRSPTSPLTPHFSCTCPSGFTGDRCQTHLEELCPPSFCSNGGHCYVQASGRPQCSCEPGWTGEQCQLRDFCSANPCANGGVCLATYPQIQCRCPPGFEGHTCERDINECFLEPGPCPQGTSCHNTLGSYQCLCPVGQEGPQCKLRKGACPPGSCLNGGTCQLVPEGHSTFHLCLCPPGFTGLDCEMNPDDCVRHQCQNGATCLDGLDTYTCLCPKTWKGWDCSEDIDECEARGPPRCRNGGTCQNTAGSFHCVCVSGWGGAGCEENLDDCAAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHVNAQCSTNPLTGSTLCICQPGYSGSTCHQDLDECQMAQQGPSPCEHGGSCINTPGSFNCLCLPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGRLCEVEVNECTSNPCLNQAACHDLLNGFQCLCLPGFTGARCEKDMDECSSTPCANGGRCRDQPGAFYCECLPGFEGPHCEKEVDECLSDPCPVGASCLDLPGAFFCLCRPGFTGQLCEVPLCTPNMCQPGQQCQGQEHRAPCLCPDGSPGCVPAEDNCPCHHGHCQRSLCVCDEGWTGPECETELGGCISTPCAHGGTCHPQPSGYNCTCPAGYMGLTCSEEVTACHSGPCLNGGSCSIRPEGYSCTCLPSHTGRHCQTAVDHCVSASCLNGGTCVNKPGTFFCLCATGFQGLHCEEKTNPSCADSPCRNKATCQDTPRGARCLCSPGYTGSSCQTLIDLCARKPCPHTARCLQSGPSFQCLCLQGWTGALCDFPLSCQKAAMSQGIEISGLCQNGGLCIDTGSSYFCRCPPGFQGKLCQDNVNPCEPNPCHHGSTCVPQPSGYVCQCAPGYEGQNCSKVLDACQSQPCHNHGTCTSRPGGFHCACPPGFVGLRCEGDVDECLDRPCHPSGTAACHSLANAFYCQCLPGHTGQRCEVEMDLCQSQPCSNGGSCEITTGPPPGFTCHCPKGFEGPTCSHKALSCGIHHCHNGGLCLPSPKPGSPPLCACLSGFGGPDCLTPPAPPGCGPPSPCLHNGTCTETPGLGNPGFQCTCPPDSPGPRCQRPGASGCEGRGGDGTCDAGCSGPGGDWDGGDCSLGVPDPWKGCPPHSQCWLLFRDGRCHPQCDSEECLFDGYDCEIPLTCIPAYDQYCRDHFHNGHCEKGCNNAECGWDGGDCRPEGEDSEGRPSLALLVVLRPPALDQQLLALARVLSLTLRVGLWVRKDSEGRNMVFPYPGTRAKEELSGARDSSSWERQAPPTQPLGKETESLGAGFVVVMGVDLSRCGPEHPASRCPWDSGLLLRFLAAMAAVGALEPLLPGPLLAAHPQAGTRPSANQLPWPILCSPVVGVLLLALGALLVLQLIRRRRREHGALWLPPGFIRRPQTQQAPHRRRPPLGEDNIGLKALKPEAEVDEDGVAMCSGPEEGEAEETASASRCQLWPLNSGCGELPQAAMLTPPQECESEVLDVDTCGPDGVTPLMSAVFCGGVQSTTGASPQRLGLGNLEPWEPLLDRGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHTAVAADAREVCQLLLASRQTTVDARTEDGTTPLMLAARLAVEDLVEELIAARADVGARDKRGKTALHWAAAVNNARAARSLLQAGADKDAQDSREQTPLFLAAREGAVEVAQLLLELGAARGLRDQAGLAPGDVARQRSHWDLLTLLEGAGPTTQEARAHARTTPGGGAAPRCRTLSAGARPRGGGACLQARTWSVDLGARGGKVYARCRSRSGSCGGPTTRGRRFSAGSRGRRGARASQDDWPRDWVALEACGSACSAPIPPPSLTPSPERGSPQVAWGLPVHQEIPLNSVVRNLN", "length": 1964 }, "evidence": [ { "id": "HGNC:7884", "url": "https://alliancegenome.org/gene/HGNC:7884#orthology", "database": "AGR" }, { "id": "RGD:1303282", "url": "https://alliancegenome.org/gene/RGD:1303282#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6MG88-1", "protein_name": "G protein-signaling modulator 3", "gene_name": "Gpsm3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAERPQEDGEQSLPQDDQGWPPVNSTARPWRSAPPSPPPPGTRHTALGPRSGSLLSLQTELLLDLVAEAQSRRLEEQRAAFHTPKVPPSLAPTPPRLLEDKEQLYSTILSHQCQRIEAQRSDPPLPPGGQELLELLLRVQGGGRMEDQRSRPPTHTC", "length": 158 }, "evidence": [ { "id": "HGNC:7884", "url": "https://alliancegenome.org/gene/HGNC:7884#orthology", "database": "AGR" }, { "id": "RGD:1303282", "url": "https://alliancegenome.org/gene/RGD:1303282#orthology", "database": "AGR" }, { "id": "FB:FBgn0021742", "url": "https://alliancegenome.org/gene/FB:FBgn0021742#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6UXI9-1", "protein_name": "Nephronectin", "gene_name": "NPNT", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDFLLALVLVSSLYLQAAAEFDGRWPRQIVSSIGLCRYGGRIDCCWGWARQSWGQCQPVCQPRCKHGECIGPNKCKCHPGYAGKTCNQDLNECGLKPRPCKHRCMNTYGSYKCYCLNGYMLMPDGSCSSALTCSMANCQYGCDVVKGQIRCQCPSPGLQLAPDGRTCVDVDECATGRASCPRFRQCVNTFGSYICKCHKGFDLMYIGGKYQCHDIDECSLGQYQCSSFARCYNIRGSYKCKCKEGYQGDGLTCVYIPKVMIEPSGPIHVPKGNGTILKGDTGNNNWIPDVGSTWWPPKTPYIPPIITNRPTSKPTTRPTPKPTPIPTPPPPPPLPTELRTPLPPTTPERPTTGLTTIAPAASTPPGGITVDNRVQTDPQKPRGDVFIPRQPSNDLFEIFEIERGVSADDEAKDDPGVLVHSCNFDHGLCGWIREKDNDLHWEPIRDPAGGQYLTVSAAKAPGGKAARLVLPLGRLMHSGDLCLSFRHKVTGLHSGTLQVFVRKHGAHGAALWGRNGGHGWRQTQITLRGADIKSVVFKGEKRRGHTGEIGLDDVSLKKGHCSEER", "length": 565 }, "evidence": [ { "id": "Q9VZ44", "url": "https://omabrowser.org/oma/group/Q9VZ44/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q91V88-1", "protein_name": "Nephronectin", "gene_name": "Npnt", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAVLLAAVLASSLYLQVAADFDGRWPRQIVSSIGLCRYGGRIDCCWGWARQSWGQCQPVCQPQCKHGECVGPNKCKCHPGFAGKTCNQDLNECGLKPRPCKHRCMNTFGSYKCYCLNGYMLLPDGSCSSALSCSMANCQYGCDVVKGQVRCQCPSPGLQLAPDGRTCVDIDECATGRVSCPRFRQCVNTFGSYICKCHTGFDLMYIGGKYQCHDIDECSLGQHQCSSYARCYNIHGSYKCQCRDGYEGDGLNCVYIPKVMIEPSGPIHMPERNGTISKGDGGHANRIPDAGSTRWPLKTPYIPPVITNRPTSKPTTRPTPNPTPQPTPPPPPPLPTEPRTTPLPPTPERPSTRPTTIAPATSTTTRVITVDNRIQTDPQKPRGDVFIPRQPTNDLFEIFEIERGVSADEEVKDDPGILIHSCNFDHGLCGWIREKDSDLHWETARDPAGGQYLTVSAAKAPGGKAARLVLRLGHLMHSGDLCLSFRHKVTGLHSGTLQVFVRKHGTHGAALWGRNGGHGWRQTQITLRGADVKSVIFKGEKRRGHTGEIGLDDVSLKRGRC", "length": 561 }, "evidence": [ { "id": "Q9VZ44", "url": "https://omabrowser.org/oma/group/Q9VZ44/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q99466-1", "protein_name": "Neurogenic locus notch homolog protein 4", "gene_name": "NOTCH4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQPPSLLLLLLLLLLLCVSVVRPRGLLCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGACDAGCSGPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECLFDGYDCETPPACTPAYDQYCHDHFHNGHCEKGCNTAECGWDGGDCRPEDGDPEWGPSLALLVVLSPPALDQQLFALARVLSLTLRVGLWVRKDRDGRDMVYPYPGARAEEKLGGTRDPTYQERAAPQTQPLGKETDSLSAGFVVVMGVDLSRCGPDHPASRCPWDPGLLLRFLAAMAAVGALEPLLPGPLLAVHPHAGTAPPANQLPWPVLCSPVAGVILLALGALLVLQLIRRRRREHGALWLPPGFTRRPRTQSAPHRRRPPLGEDSIGLKALKPKAEVDEDGVVMCSGPEEGEEVGQAEETGPPSTCQLWSLSGGCGALPQAAMLTPPQESEMEAPDLDTRGPDGVTPLMSAVCCGEVQSGTFQGAWLGCPEPWEPLLDGGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAADAREVCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTALHWAAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELRDQAGLAPADVAHQRNHWDLLTLLEGAGPPEARHKATPGREAGPFPRARTVSVSVPPHGGGALPRCRTLSAGAGPRGGGACLQARTWSVDLAARGGGAYSHCRSLSGVGAGGGPTPRGRRFSAGMRGPRPNPAIMRGRYGVAAGRGGRVSTDDWPCDWVALGACGSASNIPIPPPCLTPSPERGSPQLDCGPPALQEMPINQGGEGKK", "length": 2003 }, "evidence": [ { "id": "HGNC:7884", "url": "https://alliancegenome.org/gene/HGNC:7884#orthology", "database": "AGR" }, { "id": "RGD:1303282", "url": "https://alliancegenome.org/gene/RGD:1303282#orthology", "database": "AGR" }, { "id": "FB:FBgn0021742", "url": "https://alliancegenome.org/gene/FB:FBgn0021742#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "system development", "id": "GO:0048731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048731", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ44", "url": "https://www.uniprot.org/uniprotkb/Q9VZ44" } ], "pmid": "" }, { "name": "Notch signaling pathway", "id": "GO:0007219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007219", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ44", "url": "https://www.uniprot.org/uniprotkb/Q9VZ44" } ], "pmid": "" }, { "name": "negative regulation of Notch signaling pathway", "id": "GO:0045746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045746", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ44", "url": "https://www.uniprot.org/uniprotkb/Q9VZ44" } ], "pmid": "" }, { "name": "animal organ development", "id": "GO:0048513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048513", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ44", "url": "https://www.uniprot.org/uniprotkb/Q9VZ44" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ44", "url": "https://www.uniprot.org/uniprotkb/Q9VZ44" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "Notch binding", "id": "GO:0005112", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005112", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ44", "url": "https://www.uniprot.org/uniprotkb/Q9VZ44" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 384, "end_pos": 386, "annotation": "n_glycosylation_sequon" }, { "start_pos": 410, "end_pos": 412, "annotation": "n_glycosylation_sequon" }, { "start_pos": 426, "end_pos": 428, "annotation": "n_glycosylation_sequon" }, { "start_pos": 455, "end_pos": 457, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VZ44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ44" }, { "id": "PS51051", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51051" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DSL", "eco_id": "ECO_0000259", "start_pos": 37, "end_pos": 79, "start_aa": "Asn", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q9VZ44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ44" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 274, "end_pos": 315, "start_aa": "Lys", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 334 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 384, "end_pos": 386 }, { "start_pos": 410, "end_pos": 412 }, { "start_pos": 426, "end_pos": 428 }, { "start_pos": 455, "end_pos": 457 } ] }, "class_list": [], "section_stats": [ { 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[ { "id": "Q9VZ61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ61/entry#names_and_taxonomy" } ] }, { "name": "Sister of feo, isoform B", "type": "synonym", "evidence": [ { "id": "Q9VZ61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ61/entry#names_and_taxonomy" } ] }, { "name": "sister of feo, isoform B", "type": "synonym", "evidence": [ { "id": "NP_001285092", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285092" } ] }, { "name": "sofe-PB", "type": "synonym", "evidence": [ { "id": "NP_001285092", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285092" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VZ61", "url": "https://www.uniprot.org/uniprotkb/Q9VZ61" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "sofe", "url": "https://www.uniprot.org/uniprotkb/Q9VZ61", "locus": { "chromosome": "X", "start_pos": 10855000, "end_pos": 10857413, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0030242", "url": "https://www.ensemblgenomes.org/id/FBgn0030242" } ] } } ], "crossref": [ { "id": "FB:FBgn0030242", "url": "https://alliancegenome.org/gene/FB:FBgn0030242", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0030242", "url": "https://bgee.org/?page=gene&gene_id=FBgn0030242", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0030242", "url": "https://flybase.org/reports/FBgn0030242", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "32016", "url": "https://www.ncbi.nlm.nih.gov/gene/32016", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007145", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007145", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015898", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015898", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG1655", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG1655", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IDVQINC", "url": "https://omabrowser.org/oma/group/IDVQINC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VZ61", "url": "https://www.orthodb.org/?gene=Q9VZ61", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19321", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19321", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19321:SF41", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19321:SF41", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03999", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03999", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001285092", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285092", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VZ61", "url": "https://www.uniprot.org/uniprotkb/Q9VZ61", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VZ61-1", "url": "https://www.uniprot.org/uniprotkb/Q9VZ61-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLSSEHKARILALTAEHFDELHAMWSRMFEPQACEDCLARLKDHVHTFYTDLRKETSDKEQGILNDIAVLRNEASGLRRLLHKAVDIGERPDDVPMEIWYIKLEKYIEQLRKELVSRRAEIRELLHQQQQLCDELGEQPLSLLADPLPLPEEMDPFREHLAQLRDQRVQRLRDMDELRQNIKRNIKLLELQLRTDSEKRLLNADNHKLTPYAYVRLQEMDKEFADQVQDLIDRIDEMRGKIECLWQRLRMTDEYAMRRVREATSYNQCTYDILREELERCQAMRQQNLIAFIEQLRIEINEWWDLSLKSTEERRRFTTYYCDTQTEDVLEQFEKELDNLKEFYNSNRKIFELYANRGELWTRMEALEAKANDPNRFNNRGGQLLKEEKERKTIMSRLPKIDQQITELVQVYMSETHTPFLVHGVDILERMSADWERHRQSKKQPSAQKKDGSNTSGQMKPPMVPLTPNTQKSNRGIHGSTSSLKKTPTKANASTTAMSTGNLHKRRHPQHHNTNSPQPAAAAKRNLIASLECNNASRKVCVNGQKLLKSPQRKVRVLEYSVRRGKGSGRPSTGSRNPQKIRPIPKIHVRPPSGEENESPDEEAVVAI", "length": 607, "header": "tr|Q9VZ61-1|Q9VZ61_DROME Isoform 1 of Sister of feo, isoform A OS=Drosophila melanogaster OX=7227 GN=sofe PE=4 SV=2 CANONICAL=Q9VZ61-1" }, "isoforms": [ { "isoform_ac": "Q9VZ61-1", "url": "https://www.uniprot.org/uniprotkb/Q9VZ61/entry#Q9VZ61-1", "sequence": { "sequence": "MLSSEHKARILALTAEHFDELHAMWSRMFEPQACEDCLARLKDHVHTFYTDLRKETSDKEQGILNDIAVLRNEASGLRRLLHKAVDIGERPDDVPMEIWYIKLEKYIEQLRKELVSRRAEIRELLHQQQQLCDELGEQPLSLLADPLPLPEEMDPFREHLAQLRDQRVQRLRDMDELRQNIKRNIKLLELQLRTDSEKRLLNADNHKLTPYAYVRLQEMDKEFADQVQDLIDRIDEMRGKIECLWQRLRMTDEYAMRRVREATSYNQCTYDILREELERCQAMRQQNLIAFIEQLRIEINEWWDLSLKSTEERRRFTTYYCDTQTEDVLEQFEKELDNLKEFYNSNRKIFELYANRGELWTRMEALEAKANDPNRFNNRGGQLLKEEKERKTIMSRLPKIDQQITELVQVYMSETHTPFLVHGVDILERMSADWERHRQSKKQPSAQKKDGSNTSGQMKPPMVPLTPNTQKSNRGIHGSTSSLKKTPTKANASTTAMSTGNLHKRRHPQHHNTNSPQPAAAAKRNLIASLECNNASRKVCVNGQKLLKSPQRKVRVLEYSVRRGKGSGRPSTGSRNPQKIRPIPKIHVRPPSGEENESPDEEAVVAI", "length": 607, "header": "tr|Q9VZ61-1|Q9VZ61_DROME Isoform 1 of Sister of feo, isoform A OS=Drosophila melanogaster OX=7227 GN=sofe PE=4 SV=2 CANONICAL=Q9VZ61-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ61", "url": "https://www.uniprot.org/uniprotkb/Q9VZ61" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ61", "url": "https://www.uniprot.org/uniprotkb/Q9VZ61" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ61", "url": "https://www.uniprot.org/uniprotkb/Q9VZ61" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ61", "url": "https://www.uniprot.org/uniprotkb/Q9VZ61" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ61", "url": "https://www.uniprot.org/uniprotkb/Q9VZ61" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ61", "url": "https://www.uniprot.org/uniprotkb/Q9VZ61" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ61", "url": "https://www.uniprot.org/uniprotkb/Q9VZ61" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ61", "url": "https://www.uniprot.org/uniprotkb/Q9VZ61" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ61", "url": "https://www.uniprot.org/uniprotkb/Q9VZ61" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ61", "url": "https://www.uniprot.org/uniprotkb/Q9VZ61" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ61", "url": "https://www.uniprot.org/uniprotkb/Q9VZ61" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG1655", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG1655", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6APJ5-1", "protein_name": "Protein regulator of cytokinesis 1", "gene_name": "Prc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRRSEVLADESIVCLQKALTHLREIWGLIGIPEEQRLQRTEVVKKHIKDLLDKMIAEEENLRERLLKSISICRKELSTLCSELQVKPFEEDKEITVLQLEKDLRTQVELMRKQKKERKQELKLLQEQDQELREILCMPPCDVDSTSVPTLEELNLFRQRVATLRETKESRHEQFVNIKRQIILCMEELEHTPDTSFERDVVCEDESAFCLSLENIATLQKLLKQLEVKKSQNEAECEGLRAQIRELWDRLQIPEEEREPVAAIMTGSKTKIRNALKLEVDRLEELKMQNIKQVIETIRVELAQFWDQCFYSQEQRQAFAPYYSEDYTENLLHLHDVEVIRLRNYYEAHKELFEGVQKWEESWKLFLEFERKASDPSRFTNRGGNLLKEEKERAKLQKTLPKLEEELKARIEHWEQENSTAFVVNGQKFMEYVTEQWELHRLEKERAKQERQLKNKRQTETEMLYGSAPRTPSKRPGQTPNKCGKVRKMNTTTMSTATPNSSIRPVFGGSVYRSPMSRLPPSGSKSVVTSLCSGKKTPRAARLRANKENLDLNGSILSGGYSGSTPLQRNCSIKSVASTYSEFSKDPSLSDSSTVGLQRELSKASRSDATSRILNSTNIQS", "length": 620 }, "evidence": [ { "id": "RGD:1311754", "url": "https://alliancegenome.org/gene/RGD:1311754#orthology", "database": "AGR" }, { "id": "MGI:1858961", "url": "https://alliancegenome.org/gene/MGI:1858961#orthology", "database": "AGR" }, { "id": "HGNC:9341", "url": "https://alliancegenome.org/gene/HGNC:9341#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-777", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-777#orthology", "database": "AGR" }, { "id": "FB:FBgn0030242", "url": "https://alliancegenome.org/gene/FB:FBgn0030242#orthology", "database": "AGR" }, { "id": "SGD:S000005584", "url": "https://alliancegenome.org/gene/SGD:S000005584#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M1N145-1", "protein_name": "Uncharacterized protein LOC797431", "gene_name": "prc2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTCRKSEALAFSLVTEINHAMARLVDIWDSIGIMEDQRVERMQTVKKHIDGLLHSMIMEEEALRHRIKTDIITFQKQLDTLCLELTLEPFKLEEKLTVLQMEKNLRCHVESLQKEKNERLREMNDFKKQDEELCVTLCADPYYIPTGSVPSRTQLQELKEHVERLNKEKESRVKVFSGLREDIRNLMEELGHEPESSLERESICPDADIFLLTHDNIKALKLLLSQLEIKKESLISARDSLKERAMSLWNRLSCPESEAEVFQEPAMSTLSDDIRRWQRFVEHLEELQKAQLEEVINKVRQELVVLWDKCMFGPDQRQAFDVHFCDDQYTTELLALHDSELLRMKIFYEEAQPILEDLEKWKRNWALFQEFERKAADPSRFSNRGGSLLRETKERGKVQKLLPKLEEELRGRVEDWEIVKGLSFLVYGQRVMDYISSQWEEHRLQKDKEKNERMSKKTETPQFKTPTKRAHGMTCAATPTPNKIRKTPSQLAPRSATVSSISSASSSGSSTTFLCVPGRPQLSAKRTKTTETSTGPRLPLQDFNSDKKPVQMSYSAFTSEFSRKANGDAVLNSTVKDVL", "length": 579 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-040718-435", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040718-435#orthology", "database": "AGR" }, { "id": "FB:FBgn0030242", "url": "https://alliancegenome.org/gene/FB:FBgn0030242#orthology", "database": "AGR" }, { "id": "SGD:S000005584", "url": "https://alliancegenome.org/gene/SGD:S000005584#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1PAZ7-1", "protein_name": "Protein regulator of cytokinesis 1b", "gene_name": "prc1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRKSEVIAAESVACLNKALCHLKDIWEEIGIPEDQRLERTNVVKNHVKGLLDMMIAEEESLRKRLMTSIEKCHKELSKLCLELQSPPFQEEKSGTMLQREKELRTHVEVMLKEKNQRMQALKALTEQDQDLCDLLCSQPFSISPGCVPSMEQLENFHQHISCLTAEKERRHKEFVTLKKQIILCMDDLDQLPETSFEKDVVCEDEESFCLSKENIDSLKVLLQQLENRKAENKRVCGSYREKILELWKRLQIPQEERDVISEHMTLSKKRNMEALQVEVKRLEELKLKNMQNVTETLRKEIAVYWEKCFYSADQRQAFMPYYDDDFSEELLSLHDAEIVQLKQYYEDHKELFEGVHKWEENWRLFIELEERAKDPSRFTNRGGNLLKEEKQRADIVKGLPKLEKKLKAEIEQWELEQNREFQVNGQKFMQFVSDQWELYRLEKEREKQERQLKKSKQTEEDMVYGTVIRTPTKRRFLGSTTPCKARKLNPTSSTGTSNSTIRSVIGGTVCHSPISRPPISASKGNGVKTPGHSKPPHQGLLERNKENICHLTGGVAGMTKVPASPQRNFSINSVASTYSEFQRDLSKSSKSKHVPEILNSTIIQL", "length": 605 }, "evidence": [ { "id": "RGD:1311754", "url": "https://alliancegenome.org/gene/RGD:1311754#orthology", "database": "AGR" }, { "id": "MGI:1858961", "url": "https://alliancegenome.org/gene/MGI:1858961#orthology", "database": "AGR" }, { "id": "HGNC:9341", "url": "https://alliancegenome.org/gene/HGNC:9341#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-777", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-777#orthology", "database": "AGR" }, { "id": "FB:FBgn0030242", "url": "https://alliancegenome.org/gene/FB:FBgn0030242#orthology", "database": "AGR" }, { "id": "SGD:S000005584", "url": "https://alliancegenome.org/gene/SGD:S000005584#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O43663-1", "protein_name": "Protein regulator of cytokinesis 1", "gene_name": "PRC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRRSEVLAEESIVCLQKALNHLREIWELIGIPEDQRLQRTEVVKKHIKELLDMMIAEEESLKERLIKSISVCQKELNTLCSELHVEPFQEEGETTILQLEKDLRTQVELMRKQKKERKQELKLLQEQDQELCEILCMPHYDIDSASVPSLEELNQFRQHVTTLRETKASRREEFVSIKRQIILCMEALDHTPDTSFERDVVCEDEDAFCLSLENIATLQKLLRQLEMQKSQNEAVCEGLRTQIRELWDRLQIPEEEREAVATIMSGSKAKVRKALQLEVDRLEELKMQNMKKVIEAIRVELVQYWDQCFYSQEQRQAFAPFCAEDYTESLLQLHDAEIVRLKNYYEVHKELFEGVQKWEETWRLFLEFERKASDPNRFTNRGGNLLKEEKQRAKLQKMLPKLEEELKARIELWEQEHSKAFMVNGQKFMEYVAEQWEMHRLEKERAKQERQLKNKKQTETEMLYGSAPRTPSKRRGLAPNTPGKARKLNTTTMSNATANSSIRPIFGGTVYHSPVSRLPPSGSKPVAASTCSGKKTPRTGRHGANKENLELNGSILSGGYPGSAPLQRNFSINSVASTYSEFAKDPSLSDSSTVGLQRELSKASKSDATSGILNSTNIQS", "length": 620 }, "evidence": [ { "id": "RGD:1311754", "url": "https://alliancegenome.org/gene/RGD:1311754#orthology", "database": "AGR" }, { "id": "MGI:1858961", "url": "https://alliancegenome.org/gene/MGI:1858961#orthology", "database": "AGR" }, { "id": "HGNC:9341", "url": "https://alliancegenome.org/gene/HGNC:9341#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-777", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-777#orthology", "database": "AGR" }, { "id": "FB:FBgn0030242", "url": "https://alliancegenome.org/gene/FB:FBgn0030242#orthology", "database": "AGR" }, { "id": "SGD:S000005584", "url": "https://alliancegenome.org/gene/SGD:S000005584#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P50275-1", "protein_name": "Anaphase spindle elongation protein", "gene_name": "ASE1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "METATSSPLPIKSRRNSENSGSTTVIPHMNPSLATPLTVSTMVNQSNSKEFMKLTPVRIRDFGSPLKNVSTNYHFLDSENGKGNTMDNMYRENFILISKDLEKLLENLNVIYQNIGYSNTEIITKEKIIFTTISNSIKQFFEQADEELKRLSAENGIEQDILNNILERINDPSGIKTIPDLYIRNAILLQESKTVPQSPKKPLSLLSKKAALDTAKKFVLGSFLPRLRDYLKSLITLKHLIQSVKENLPGLTEADNEAIAEFPELSTLTAYLLQIENGKGDIGLSMKFIIDNRKDILKGSAFKTINEESVKHMNEVIKIYEEEYERRFKSVLTKKVSISSICEQLGTPLATLIGEDFEQDLRSYGEEENSTSEIPNFHPVDRERMSKIDITLEKLQAIHKERADKKRLLMEQCQKLWTRLKISQEYIKTFMRNNSSLSTESLGRISKEVMRLEAMKKKLIKKLISDSWDKIQELWRTLQYSEESRSKFIIVFEELRNSATTLQEDELLLETCENELKRLEEKLTLYKPILKLISDFESLQEDQEFLERSSKDSSRLLSRNSHKILLTEEKMRKRITRHFPRVINDLRIKLEEADGLFDQPFLFKGKPLSEAIDIQQQEIEAKYPRCRVRMQRSKKGKCGANKENKVIKNTFKATESSIRVPIGLNLNDANITYKTPSKKTIQGLTKNDLSQENSLARHMQGTTKLSSPNRRATRLLAPTVISRNSKGNIERPTLNRNRSSDLSSSPRINHTHGEHAVKPRQLFPIPLNKVDTKGSHIPQLTKEKALELLKRSTGTTGKENVRSPERKSSLEDYAQKLSSPYKEPEHSIYKLSMSPEGKFQLNIQQKDIESGFDDTSMMEDENDKDFITWKNEQVSKLNGFSFTDI", "length": 885 }, "evidence": [ { "id": "RGD:1311754", "url": "https://alliancegenome.org/gene/RGD:1311754#orthology", "database": "AGR" }, { "id": "MGI:1858961", "url": "https://alliancegenome.org/gene/MGI:1858961#orthology", "database": "AGR" }, { "id": "HGNC:9341", "url": "https://alliancegenome.org/gene/HGNC:9341#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040718-435", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040718-435#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-777", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-777#orthology", "database": "AGR" }, { "id": "FB:FBgn0030242", "url": "https://alliancegenome.org/gene/FB:FBgn0030242#orthology", "database": "AGR" }, { "id": "SGD:S000005584", "url": "https://alliancegenome.org/gene/SGD:S000005584#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q99K43-1", "protein_name": "Protein regulator of cytokinesis 1", "gene_name": "Prc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRRSEVLADESITCLQKALTHLREIWELIGIPEEQRLQRTEVVKKHIKDLLDRMIAEEESLRERLLKSISICQKELSTLCSELQVKPFQEEKDTTILQLEKDLRTQVELMRKQKKERKQELKLLQEQEQELRDILCMPPCDVDSTSVPTLEELKLFRQRVATLRETKESRREEFVNIKKQIILCMEELEHSPDTSFERDVVCEDESAFCLSLENIATLQKLLKQLEMKKSQNEAECEGLRTQIRELWDRLQIPEEEREPVEAIMTGSKTKIRNALKLEVDRLEELKMQNIKQVIEKIRVELAQFWDQCFYSQEQRQAFAPYYSEDYTENLLHLHDAEIVRLRNYYDVHKELFQGVQKWEESWKLFLEFERKASDPGRFTNRGGNLLKEEKERAKLQKTLPKLEEELKARIEQWEQEHSTAFVVNGQKFMEYVTEQWELHRLEKERAKQERQLKNKKQTEAEMLYGSTPRTPSKRPGQTPKKSGKMNTTTMSSATPNSSIRPVFGGSVYRSPMSRLPPSGSKSVVTSLCSGKKTPRAAQLRANKENLDLNGSILSGGYPGSTPLQHNCSIKSVASTYSEFSRELSKASRSDATSRILNSTNIQS", "length": 603 }, "evidence": [ { "id": "RGD:1311754", "url": "https://alliancegenome.org/gene/RGD:1311754#orthology", "database": "AGR" }, { "id": "MGI:1858961", "url": "https://alliancegenome.org/gene/MGI:1858961#orthology", "database": "AGR" }, { "id": "HGNC:9341", "url": "https://alliancegenome.org/gene/HGNC:9341#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-777", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-777#orthology", "database": "AGR" }, { "id": "FB:FBgn0030242", "url": "https://alliancegenome.org/gene/FB:FBgn0030242#orthology", "database": "AGR" }, { "id": "SGD:S000005584", "url": "https://alliancegenome.org/gene/SGD:S000005584#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VZ62-1", "protein_name": "Fascetto", "gene_name": "feo", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNSPSAIAVKAQILEMTGEHVDQLHAMWSQLFEVKTCGEFLLRLKDHANSFFTDLLNESREKQQAILNDIAALRAEATDLTRLLHEPLDIGERPESMPLVVWELKLDKSIEHLRDQLARRRAEICELLLQQEQLCEELGELPLPLLADPLPLPEEMDAFRNRLGQLRDQRVLRLKEMDQLRQAIKHDMKLLECLPQTDTEERLLNQVDHCLTPETFELLRNMQKNFADQVKELRERIDDMREKIHVLWDRLQETDEYAMRRVREATTYTQRTYDVLREELQRCQALRRQNLKTFIEQLRIEIKEMWDLTLKSQQERKRFSNYYNDWYNEDLLELHELELDDLKTFYNKNKEIFDLYESRAELWSRMEALEAKASEPNRFNNRGGQLLKEEKERKAITSKLPKIEQQITELVQAYEAQENTPFLVHGENILERMAADWERHRQAKQQSSARKKAPPSASKIMPPPATGSTAPRTPRTLRNMSTLSSSTMSLRKTPSQQHLRPLNITKSTGNLHKRLNPSGLQTGPKTPNAKRSLMNTLNSMKASPAKHLLAPSQQHNQLKSTKSPLKRVRVLDNTLRRSGGMGRRSIGTRSSKKARTKSNDQNAPPDSSDYTTDENPEQGVSYDEFQPTSRSSMLPRQRHQLAVPRTRRAEMNANLPVPRESLMIVQPRRQF", "length": 671 }, "evidence": [ { "id": "RGD:1311754", "url": "https://alliancegenome.org/gene/RGD:1311754#orthology", "database": "AGR" }, { "id": "MGI:1858961", "url": "https://alliancegenome.org/gene/MGI:1858961#orthology", "database": "AGR" }, { "id": "HGNC:9341", "url": "https://alliancegenome.org/gene/HGNC:9341#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040718-435", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040718-435#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-777", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-777#orthology", "database": "AGR" }, { "id": "SGD:S000005584", "url": "https://alliancegenome.org/gene/SGD:S000005584#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ61", "url": "https://www.uniprot.org/uniprotkb/Q9VZ61" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ61", "url": "https://www.uniprot.org/uniprotkb/Q9VZ61" } ], "pmid": "" }, { "name": "mitotic spindle midzone", "id": "GO:1990023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990023", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ61", "url": "https://www.uniprot.org/uniprotkb/Q9VZ61" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ61", "url": "https://www.uniprot.org/uniprotkb/Q9VZ61" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ61", "url": "https://www.uniprot.org/uniprotkb/Q9VZ61" } ], "pmid": "" }, { "name": "mitotic spindle midzone assembly", "id": "GO:0051256", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051256", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ61", "url": "https://www.uniprot.org/uniprotkb/Q9VZ61" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ61", "url": "https://www.uniprot.org/uniprotkb/Q9VZ61" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 453, "end_pos": 455, "annotation": "n_glycosylation_sequon" }, { "start_pos": 491, "end_pos": 493, "annotation": "n_glycosylation_sequon" }, { "start_pos": 534, "end_pos": 536, "annotation": "n_glycosylation_sequon" }, { "start_pos": 596, "end_pos": 598, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VZ61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ61" }, { "id": "PS50058", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50058" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G protein gamma", "eco_id": "ECO_0000259", "start_pos": 103, "end_pos": 160, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 453, "end_pos": 455 }, { "start_pos": 491, "end_pos": 493 }, { "start_pos": 534, "end_pos": 536 }, { "start_pos": 596, "end_pos": 598 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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"uniprot_canonical_ac": "Q9VZ73-1", "uniprot_ac": "Q9VZ73", "uniprot_id": "Q9VZ73_DROME", "mass": { "chemical_mass": 21335.0, "monoisotopic_mass": 21335.0 }, "refseq": { "ac": "NP_647941", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647941" }, "gene_names": [ { "name": "Dmel\\CG17030", "type": "recommended", "evidence": [ { "id": "Q9VZ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ73" } ] }, { "name": "CG17030", "type": "synonym", "evidence": [ { "id": "NP_647941", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647941" }, { "id": "Q9VZ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ73" } ] }, { "name": "Dmel\\CG17030", "type": "synonym", "evidence": [ { "id": "NP_647941", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647941" } ] }, { "name": "Dmel_CG17030", "type": "synonym", "evidence": [ { "id": "Q9VZ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ73" } ] } ], "protein_names": [ { "name": "Ubiquitin-conjugating enzyme E2-18 kDa", "type": "recommended", "evidence": [ { "id": "Q9VZ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ73/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.23", "type": "synonym", "evidence": [ { "id": "Q9VZ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ73/entry#names_and_taxonomy" } ] }, { "name": "CG17030-PA", "type": "synonym", "evidence": [ { "id": "NP_647941", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647941" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_647941", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647941" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VZ73", "url": "https://www.uniprot.org/uniprotkb/Q9VZ73" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG17030", "url": "https://www.uniprot.org/uniprotkb/Q9VZ73", "locus": { "chromosome": "3L", "start_pos": 4980003, "end_pos": 4980769, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0035584", "url": "https://www.ensemblgenomes.org/id/FBgn0035584" } ] } } ], "crossref": [ { "id": "FB:FBgn0035584", "url": "https://alliancegenome.org/gene/FB:FBgn0035584", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0035584", "url": "https://bgee.org/?page=gene&gene_id=FBgn0035584", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd23801", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23801", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0035584", "url": "https://flybase.org/reports/FBgn0035584", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "38591", "url": "https://www.ncbi.nlm.nih.gov/gene/38591", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000608", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000608", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050113", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050113", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG17030", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG17030", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "INDPQPD", "url": "https://omabrowser.org/oma/group/INDPQPD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VZ73", "url": "https://www.orthodb.org/?gene=Q9VZ73", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24067", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24067", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00179", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00179", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_647941", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647941", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VZ73", "url": "https://www.uniprot.org/uniprotkb/Q9VZ73", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VZ73-1", "url": "https://www.uniprot.org/uniprotkb/Q9VZ73-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAKKEEPLMDGPKRMNRELALMLEDKQNLQFRNLLVEPNNIYKWTGLLMPVAPPYDKGAYKMEIDFPLDYPFKPPRIHINTRMYHLNVNERGQVCVPILEVEHWIPTTRIDQVLQVLLATINDPQPENAWHIEMAGEYRNDPVRFFKMADAWVQKYSEPRPTEEELAKFARKRKKAMTKK", "length": 180, "header": "tr|Q9VZ73-1|Q9VZ73_DROME Isoform 1 of Ubiquitin-conjugating enzyme E2-18 kDa OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG17030 PE=4 SV=1 CANONICAL=Q9VZ73-1" }, "isoforms": [ { "isoform_ac": "Q9VZ73-1", "url": "https://www.uniprot.org/uniprotkb/Q9VZ73/entry#Q9VZ73-1", "sequence": { "sequence": "MAKKEEPLMDGPKRMNRELALMLEDKQNLQFRNLLVEPNNIYKWTGLLMPVAPPYDKGAYKMEIDFPLDYPFKPPRIHINTRMYHLNVNERGQVCVPILEVEHWIPTTRIDQVLQVLLATINDPQPENAWHIEMAGEYRNDPVRFFKMADAWVQKYSEPRPTEEELAKFARKRKKAMTKK", "length": 180, "header": "tr|Q9VZ73-1|Q9VZ73_DROME Isoform 1 of Ubiquitin-conjugating enzyme E2-18 kDa OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG17030 PE=4 SV=1 CANONICAL=Q9VZ73-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ73", "url": "https://www.uniprot.org/uniprotkb/Q9VZ73" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ73", "url": "https://www.uniprot.org/uniprotkb/Q9VZ73" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ73", "url": "https://www.uniprot.org/uniprotkb/Q9VZ73" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ73", "url": "https://www.uniprot.org/uniprotkb/Q9VZ73" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ73", "url": "https://www.uniprot.org/uniprotkb/Q9VZ73" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ73", "url": "https://www.uniprot.org/uniprotkb/Q9VZ73" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ73", "url": "https://www.uniprot.org/uniprotkb/Q9VZ73" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ73", "url": "https://www.uniprot.org/uniprotkb/Q9VZ73" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ73", "url": "https://www.uniprot.org/uniprotkb/Q9VZ73" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ73", "url": "https://www.uniprot.org/uniprotkb/Q9VZ73" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ73", "url": "https://www.uniprot.org/uniprotkb/Q9VZ73" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG17030", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG17030", "resource": "KEGG Pathway" }, { "id": "R-DME-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "O14933-1", "protein_name": "Ubiquitin/ISG15-conjugating enzyme E2 L6", "gene_name": "UBE2L6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMASMRVVKELEDLQKKPPPYLRNLSSDDANVLVWHALLLPDQPPYHLKAFNLRISFPPEYPFKPPMIKFTTKIYHPNVDENGQICLPIISSENWKPCTKTCQVLEALNVLVNRPNIREPLRMDLADLLTQNPELFRKNAEEFTLRFGVDRPS", "length": 153 }, "evidence": [ { "id": "HGNC:12490", "url": "https://alliancegenome.org/gene/HGNC:12490#orthology", "database": "AGR" }, { "id": "MGI:1914500", "url": "https://alliancegenome.org/gene/MGI:1914500#orthology", "database": "AGR" }, { "id": "RGD:1307960", "url": "https://alliancegenome.org/gene/RGD:1307960#orthology", "database": "AGR" }, { "id": "FB:FBgn0035584", "url": "https://alliancegenome.org/gene/FB:FBgn0035584#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P52487-1", "protein_name": "Ubiquitin-conjugating enzyme E2-18 kDa", "gene_name": "Ubc84D", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAATRRLTRELSDLVEAKMSTLRNIESSDESLLMWTGLLVPEKAPYNKGAFRIEINFPPQYPFMPPKILFKTKIYHPNVDEKGEVCLPIISTDNWKPTTRTEQVLQALVAIVHNPEPEHPLRSDLAEEFVREHKKFMKTAEEFTKKNAEKRPE", "length": 153 }, "evidence": [ { "id": "HGNC:12490", "url": "https://alliancegenome.org/gene/HGNC:12490#orthology", "database": "AGR" }, { "id": "MGI:1914500", "url": "https://alliancegenome.org/gene/MGI:1914500#orthology", "database": "AGR" }, { "id": "RGD:1307960", "url": "https://alliancegenome.org/gene/RGD:1307960#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q4V8J2-1", "protein_name": "Ubiquitin/ISG15-conjugating enzyme E2 L6", "gene_name": "Ube2l6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTASKRVAKELDDLSKELPPYLRHLSSDDANVLVWHMLLLPDQLPYRLKAFGLRIDFPREYPLKPPTLRFTTKIYHPNISEDGLVCLPLISTENWKPYTKAYQVLEALNILVSRPNLEEPVRLELADLLTQDPEMFRKKAEEFTLQYGVDRPS", "length": 153 }, "evidence": [ { "id": "HGNC:12490", "url": "https://alliancegenome.org/gene/HGNC:12490#orthology", "database": "AGR" }, { "id": "MGI:1914500", "url": "https://alliancegenome.org/gene/MGI:1914500#orthology", "database": "AGR" }, { "id": "RGD:1307960", "url": "https://alliancegenome.org/gene/RGD:1307960#orthology", "database": "AGR" }, { "id": "FB:FBgn0035584", "url": "https://alliancegenome.org/gene/FB:FBgn0035584#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7K738-1", "protein_name": "Ubiquitin-conjugating enzyme E2-18 kDa", "gene_name": "Ubc10", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTAPRRLRKELSDLQGNALKSFRDIKADDDNLLRWTGLIVPDNPPYNKGAFRIEINFPAEYPFKPPKINFKTRIYHPNIDEKGQVCLPIISTENWKPATRTDQVVQALVDLINDPEPEHPLRAELAEEFLKDRKKFVKNAEDYTKKHSEKRPAD", "length": 154 }, "evidence": [ { "id": "HGNC:12490", "url": "https://alliancegenome.org/gene/HGNC:12490#orthology", "database": "AGR" }, { "id": "RGD:1307960", "url": "https://alliancegenome.org/gene/RGD:1307960#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9QZU9-1", "protein_name": "Ubiquitin/ISG15-conjugating enzyme E2 L6", "gene_name": "Ube2l6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMASKRVAKELESLSKELPPYLRQLSSDDANVLVWHMLLLPDQLPYGLKAFQVRIDFPREYPFKPPTLRFTTKIYHPNVREDGLVCLPLISNENWKPYTKPYQVLEALNVLVSKPNLEEPVRLELADLLTQNPEMFRKKAEEFTLKFGVDRPS", "length": 153 }, "evidence": [ { "id": "HGNC:12490", "url": "https://alliancegenome.org/gene/HGNC:12490#orthology", "database": "AGR" }, { "id": "MGI:1914500", "url": "https://alliancegenome.org/gene/MGI:1914500#orthology", "database": "AGR" }, { "id": "RGD:1307960", "url": "https://alliancegenome.org/gene/RGD:1307960#orthology", "database": "AGR" }, { "id": "FB:FBgn0035584", "url": "https://alliancegenome.org/gene/FB:FBgn0035584#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ73", "url": "https://www.uniprot.org/uniprotkb/Q9VZ73" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ73", "url": "https://www.uniprot.org/uniprotkb/Q9VZ73" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ73", "url": "https://www.uniprot.org/uniprotkb/Q9VZ73" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ73", "url": "https://www.uniprot.org/uniprotkb/Q9VZ73" } ], "pmid": "" }, { "name": "ubiquitin conjugating enzyme activity", "id": "GO:0061631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061631", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ73", "url": "https://www.uniprot.org/uniprotkb/Q9VZ73" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-DME-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VJ14-1", "Q9VUV7-1", "Q9VXE8-1", "Q9VY98-1", "Q9W4W4-1", "Q9XYW6-1", "M9MRI4-1", "O76924-1", "P35128-1", "P52485-1", "Q9VE61-1", "Q9VI55-1", "Q9VSF3-1", "Q9VX25-1", "X2JF73-1", "P21461-1", "P52486-1", "Q8T3Y0-1", "Q9V853-1", "Q9VTY6-1", "Q9VVI3-1", "Q9VW09-1", "Q9Y0H4-1", "Q9VEJ4-1", "Q9VFC4-1", "Q9VSS9-1", "Q9W326-1", "Q9W3V3-1", "M9PBE2-1", "Q9VR91-1", "A0A0B4KFY0-1", "Q9VN58-1", "Q9VP20-1", "Q9VQ67-1", "Q9VSK2-1", "A1Z8B5-1", "Q9VQ00-1", "Q9VTH1-1", "P25153-1", "P25867-1", "P52487-1", "Q7K738-1", "Q7KTX7-1", "Q9VHI7-1", "Q9VX91-1", "Q9VZ73-1", "Q9W196-1" ], "evidence": [ { "id": "R-DME-983140", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-983140" } ] }, { "id": "R-DME-983152", "name": "Transfer of ubiquitin from E1 to E2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VXE8-1", "P35128-1", "P52485-1", "Q9VSF3-1", "Q9VX25-1", "P52486-1", "Q9VTY6-1", "Q9VEJ4-1", "A1Z8B5-1", "Q9VQ00-1", "P25153-1", "P25867-1", "P52487-1", "Q7K738-1", "Q9V6U8-1", "Q9VZ73-1" ], "evidence": [ { "id": "R-DME-983152", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-983152" } ] }, { "id": "R-DME-983156", "name": "Polyubiquitination of substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VJ14-1", "Q9VUV7-1", "Q9VXE8-1", "Q9VY98-1", "Q9W4W4-1", "Q9XYW6-1", "M9MRI4-1", "O76924-1", "P35128-1", "P52485-1", "Q9VE61-1", "Q9VI55-1", "Q9VSF3-1", "Q9VX25-1", "X2JF73-1", "P21461-1", "P52486-1", "Q8T3Y0-1", "Q9V853-1", "Q9VTY6-1", "Q9VVI3-1", "Q9VW09-1", "Q9Y0H4-1", "Q9VEJ4-1", "Q9VFC4-1", "Q9VSS9-1", "Q9W326-1", "Q9W3V3-1", "M9PBE2-1", "Q9VR91-1", "A0A0B4KFY0-1", "Q9VN58-1", "Q9VP20-1", "Q9VQ67-1", "Q9VSK2-1", "A1Z8B5-1", "Q9VQ00-1", "Q9VTH1-1", "P25153-1", "P25867-1", "P52487-1", "Q7K738-1", "Q7KTX7-1", "Q9VHI7-1", "Q9VX91-1", "Q9VZ73-1", "Q9W196-1" ], "evidence": [ { "id": "R-DME-983156", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-983156" } ] }, { "id": "R-DME-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VJ14-1", "Q9VUV7-1", "Q9VXE8-1", "Q9VY98-1", "Q9W4W4-1", "Q9XYW6-1", "M9MRI4-1", "O76924-1", "P35128-1", "P52485-1", "Q9VE61-1", "Q9VI55-1", "Q9VSF3-1", "Q9VX25-1", "X2JF73-1", "P21461-1", "P52486-1", "Q8T3Y0-1", "Q9V853-1", "Q9VTY6-1", "Q9VVI3-1", "Q9VW09-1", "Q9Y0H4-1", "Q9VEJ4-1", "Q9VFC4-1", "Q9VSS9-1", "Q9W326-1", "Q9W3V3-1", "M9PBE2-1", "Q9VR91-1", "A0A0B4KFY0-1", "Q9VN58-1", "Q9VP20-1", "Q9VQ67-1", "Q9VSK2-1", "A1Z8B5-1", "Q9VQ00-1", "Q9VTH1-1", "P25153-1", "P25867-1", "P52487-1", "Q7K738-1", "Q7KTX7-1", "Q9VHI7-1", "Q9VX91-1", "Q9VZ73-1", "Q9W196-1" ], "evidence": [ { "id": "R-DME-983157", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-983157" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A0B4KFY0", "gene_name": "dnr1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A0B4KFY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFY0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A0B4KFY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFY0" } ] } ] }, { "uniprot_ac": "A1Z8B5", "gene_name": "Ube2W", "activity": [ { "ec_number": "2.3.2.25", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-N-terminal-amino acid = [E1 ubiquitin-activating enzyme]-L-cysteine + N-terminal-ubiquitinyl-[acceptor protein].", "evidence": [ { "id": "A1Z8B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1Z8B5" } ] }, { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A1Z8B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1Z8B5" } ] }, { "ec_number": "2.3.2.25", "activity": "", "evidence": [ { "id": "A1Z8B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1Z8B5" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A1Z8B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1Z8B5" } ] } ] }, { "uniprot_ac": "M9MRI4", "gene_name": "Trim9", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "M9MRI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9MRI4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "M9MRI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9MRI4" } ] } ] }, { "uniprot_ac": "M9PBE2", "gene_name": "Hakai", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "M9PBE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9PBE2" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "M9PBE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9PBE2" } ] } ] }, { "uniprot_ac": "O76924", "gene_name": "ari-2", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "O76924", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O76924" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "O76924", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O76924" } ] } ] }, { "uniprot_ac": "P21461", "gene_name": "sina", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "P21461", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21461" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "P21461", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21461" } ] } ] }, { "uniprot_ac": "P25153", "gene_name": "Ubc6", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "P25153", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P25153" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "P25153", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P25153" } ] } ] }, { "uniprot_ac": "P25867", "gene_name": "eff", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "P25867", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P25867" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "P25867", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P25867" } ] } ] }, { "uniprot_ac": "P35128", "gene_name": "ben", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "P35128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35128" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "P35128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35128" } ] } ] }, { "uniprot_ac": "P52485", "gene_name": "Ubc2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "P52485", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52485" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "P52485", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52485" } ] } ] }, { "uniprot_ac": "P52486", "gene_name": "Ubc4", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "P52486", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52486" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "P52486", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52486" } ] } ] }, { "uniprot_ac": "P52487", "gene_name": "Ubc84D", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "P52487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52487" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "P52487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52487" } ] } ] }, { "uniprot_ac": "Q7K738", "gene_name": "Ubc10", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q7K738", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7K738" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q7K738", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7K738" } ] } ] }, { "uniprot_ac": "Q7KTX7", "gene_name": "park", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "Q7KTX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7KTX7" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "Q7KTX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7KTX7" } ] } ] }, { "uniprot_ac": "Q8T3Y0", "gene_name": "sinah", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q8T3Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8T3Y0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q8T3Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8T3Y0" } ] } ] }, { "uniprot_ac": "Q9V6U8", "gene_name": "Uba3", "activity": [ { "ec_number": "6.2.1.64", "activity": "ATP + [NEDD8 protein] + [E1 NEDD8-activating enzyme]-L-cysteine = AMP + diphosphate + [E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine.", "evidence": [ { "id": "Q9V6U8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9V6U8" } ] }, { "ec_number": "6.2.1.64", "activity": "", "evidence": [ { "id": "Q9V6U8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9V6U8" } ] } ] }, { "uniprot_ac": "Q9V853", "gene_name": "Smurf", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q9V853", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9V853" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "Q9V853", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9V853" } ] } ] }, { "uniprot_ac": "Q9VE61", "gene_name": "", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q9VE61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VE61" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q9VE61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VE61" } ] } ] }, { "uniprot_ac": "Q9VEJ4", "gene_name": "Dmel\\CG5823", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q9VEJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VEJ4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q9VEJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VEJ4" } ] } ] }, { "uniprot_ac": "Q9VFC4", "gene_name": "Kpc1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q9VFC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VFC4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q9VFC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VFC4" } ] } ] }, { "uniprot_ac": "Q9VHI7", "gene_name": "Iru", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q9VHI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VHI7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q9VHI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VHI7" } ] } ] }, { "uniprot_ac": "Q9VI55", "gene_name": "Ufl1", "activity": [ { "ec_number": "2.3.2.-", "activity": "", "evidence": [ { "id": "Q9VI55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VI55" } ] } ] }, { "uniprot_ac": "Q9VJ14", "gene_name": "mib2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q9VJ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJ14" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q9VJ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJ14" } ] } ] }, { "uniprot_ac": "Q9VN58", "gene_name": "ctrip", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q9VN58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VN58" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "Q9VN58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VN58" } ] } ] }, { "uniprot_ac": "Q9VP20", "gene_name": "Mkrn1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q9VP20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VP20" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q9VP20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VP20" } ] } ] }, { "uniprot_ac": "Q9VQ00", "gene_name": "Dmel\\CG5440", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q9VQ00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQ00" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q9VQ00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQ00" } ] } ] }, { "uniprot_ac": "Q9VQ67", "gene_name": "Dmel\\CG4238", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q9VQ67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQ67" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "Q9VQ67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQ67" } ] } ] }, { "uniprot_ac": "Q9VR91", "gene_name": "HERC2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q9VR91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VR91" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "Q9VR91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VR91" } ] } ] }, { "uniprot_ac": "Q9VSF3", "gene_name": "UbcE2M", "activity": [ { "ec_number": "2.3.2.34", "activity": "[E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine + [E2 NEDD8-conjugating enzyme]-L-cysteine = [E1 NEDD8-activating enzyme]-L-cysteine + [E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine.", "evidence": [ { "id": "Q9VSF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSF3" } ] }, { "ec_number": "2.3.2.34", "activity": "", "evidence": [ { "id": "Q9VSF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSF3" } ] } ] }, { "uniprot_ac": "Q9VSK2", "gene_name": "Cbl", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q9VSK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSK2" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q9VSK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSK2" } ] } ] }, { "uniprot_ac": "Q9VSS9", "gene_name": "NM_140022.1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q9VSS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSS9" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "Q9VSS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSS9" } ] } ] }, { "uniprot_ac": "Q9VTH1", "gene_name": "Ube3a", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q9VTH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTH1" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "Q9VTH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTH1" } ] } ] }, { "uniprot_ac": "Q9VTY6", "gene_name": "vih", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q9VTY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTY6" } ] }, { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q9VTY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTY6" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q9VTY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTY6" } ] } ] }, { "uniprot_ac": "Q9VUV7", "gene_name": "elgi", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q9VUV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUV7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q9VUV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUV7" } ] } ] }, { "uniprot_ac": "Q9VVI3", "gene_name": "Nedd4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q9VVI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVI3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "Q9VVI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVI3" } ] } ] }, { "uniprot_ac": "Q9VW09", "gene_name": "Ltn1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q9VW09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VW09" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q9VW09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VW09" } ] } ] }, { "uniprot_ac": "Q9VX25", "gene_name": "", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q9VX25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VX25" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q9VX25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VX25" } ] } ] }, { "uniprot_ac": "Q9VX91", "gene_name": "Ubr1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q9VX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VX91" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q9VX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VX91" } ] } ] }, { "uniprot_ac": "Q9VXE8", "gene_name": "Ubc7", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q9VXE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXE8" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q9VXE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXE8" } ] } ] }, { "uniprot_ac": "Q9VY98", "gene_name": "Mgrn1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q9VY98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VY98" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q9VY98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VY98" } ] } ] }, { "uniprot_ac": "Q9VZ73", "gene_name": "Dmel\\CG17030", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q9VZ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ73" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q9VZ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ73" } ] } ] }, { "uniprot_ac": "Q9W196", "gene_name": "Dmel\\CG3356", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q9W196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W196" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "Q9W196", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W196" } ] } ] }, { "uniprot_ac": "Q9W326", "gene_name": "Hecw", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q9W326", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W326" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "Q9W326", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W326" } ] } ] }, { "uniprot_ac": "Q9W3V3", "gene_name": "detr", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q9W3V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3V3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q9W3V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3V3" } ] } ] }, { "uniprot_ac": "Q9W4W4", "gene_name": "Dmel\\CG2681", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q9W4W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W4W4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q9W4W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W4W4" } ] } ] }, { "uniprot_ac": "Q9XYW6", "gene_name": "STUB1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q9XYW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9XYW6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q9XYW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9XYW6" } ] } ] }, { "uniprot_ac": "Q9Y0H4", "gene_name": "Su(dx)", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q9Y0H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9Y0H4" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "Q9Y0H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9Y0H4" } ] } ] }, { "uniprot_ac": "X2JF73", "gene_name": "HUWE1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "X2JF73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/X2JF73" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "X2JF73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/X2JF73" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VZ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ73" }, { "id": "PS50127", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50127" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UBC core", "eco_id": "ECO_0000259", "start_pos": 10, "end_pos": 158, "start_aa": "Asp", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.23", "ec_name": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "2.3.2.23", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.23" } ] } ], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", 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0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VZ81-1", "uniprot_ac": "Q9VZ81", "uniprot_id": "Q9VZ81_DROME", "mass": { "chemical_mass": 140279.0, "monoisotopic_mass": 140279.0 }, "refseq": { "ac": "NP_001261433", "name": "uncharacterized protein, isoform B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261433" }, "gene_names": [ { "name": "CT33170", "type": "recommended", "evidence": [ { "id": "Q9VZ81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ81" } ] }, { "name": "CG13708", "type": "synonym", "evidence": [ { "id": "NP_001261433", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261433" }, { "id": "Q9VZ81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ81" } ] }, { "name": "CT33170", "type": "synonym", "evidence": [ { "id": "NP_001261433", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261433" } ] }, { "name": "Dmel\\CG13708", "type": "synonym", "evidence": [ { "id": "NP_001261433", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261433" }, { "id": "Q9VZ81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ81" } ] }, { "name": "Dmel_CG13708", "type": "synonym", "evidence": [ { "id": "Q9VZ81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ81" } ] } ], "protein_names": [ { "name": "Dynein axonemal assembly factor 1 homolog", "type": "recommended", "evidence": [ { "id": "Q9VZ81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ81/entry#names_and_taxonomy" } ] }, { "name": "CG13708-PB", "type": "synonym", "evidence": [ { "id": "NP_001261433", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261433" } ] }, { "name": "Defective transmitter-recycling protein", "type": "synonym", "evidence": [ { "id": "Q9VZ81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ81/entry#names_and_taxonomy" } ] }, { "name": "Leucine-rich repeat-containing protein 50 homolog", "type": "synonym", "evidence": [ { "id": "Q9VZ81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ81/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein, isoform B", "type": "synonym", "evidence": [ { "id": "NP_001261433", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261433" } ] } ], "function": [ { "annotation": "Cilium-specific protein required for cilia structures.", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ81", "url": "https://www.uniprot.org/uniprotkb/Q9VZ81#function" }, { "database": "UniProtKB", "id": "ARBA00003843", "url": "https://www.uniprot.org/uniprotkb/ARBA00003843#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VZ81", "url": "https://www.uniprot.org/uniprotkb/Q9VZ81" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "CT33170", "url": "https://www.uniprot.org/uniprotkb/Q9VZ81", "locus": { "chromosome": "3L", "start_pos": 4829092, "end_pos": 4833591, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0035577", "url": "https://www.ensemblgenomes.org/id/FBgn0035577" } ] } } ], "crossref": [ { "id": "FB:FBgn0035577", "url": "https://alliancegenome.org/gene/FB:FBgn0035577", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0035577", "url": "https://bgee.org/?page=gene&gene_id=FBgn0035577", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0035577", "url": "https://flybase.org/reports/FBgn0035577", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "38582", "url": "https://www.ncbi.nlm.nih.gov/gene/38582", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025875", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025875", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050576", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050576", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG13708", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG13708", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IDENCNK", "url": "https://omabrowser.org/oma/group/IDENCNK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VZ81", "url": "https://www.orthodb.org/?gene=Q9VZ81", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45973", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45973", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45973:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45973:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12799", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12799", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001261433", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261433", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VZ81", "url": "https://www.uniprot.org/uniprotkb/Q9VZ81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VZ81-1", "url": "https://www.uniprot.org/uniprotkb/Q9VZ81-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAKCRGRSILNDETPTPEAACPAPGPAPAATPAAANPLPHPQQQQLQQQQNYLPQTSLLKIEPFVPSFNQRLRRRPIGRSHSTLSHNVISKRPVPQQHQQQQIQQPSELQVGQQQQLKRGYAAAAQIRQQQQQQQRNLPRGVGIQRQRSKSTSSSAASNSCRPATAAVTPNTLVGSTGGTLVSGAIVTPQPNGICRIQRLPKEREELPDRINYDKRGLTAIPIFEQEPNLRLLSLQHNLINTFHIPKEVTPPPPPVPPPAVATPRESNNNKLGEYSNGNGNKEGGRSGLRGHHPGRLTRAMTNAGGNSHRLSPKSGGSPGSGSPLTTQALAINGGTAAGRSKLAKRGYNYGQAQLTPPPALRMRYGLEKSKSFVSSSLQAMKHQQQLIQRRAMLKATRAGGVVAPGGAASNLLQSCDEGSALHNSNLSLYGGCGEEEESPSVMTSISALEQLSIKNKQLSLSASYGSIFQQLVFLDLYDNQIERIANLDGLPSLSVLLLGKNRITDIGGLSSLKDTLRVLDLHGNKLTSLGSRINCLQQLKSLNLAGNQIRQINQQDFLGLRCLRELNLKRNKLRRINGFQHLVALERLWLCHNDLHRVDDMASIARATRLLEVTIENNPVSLAGDCVSFLVSYLPLLQTLSQMPITEQVRRAALAWRQHKEQAQAAPGSSEAYHNIRREEVISNARTNWELLRSQQTVVGRPKSRLTSELAKINESNEGPAGEEGEMESEESQQPKELMDELQALIKLPPIAKDLRNPHEEDGASSEASSLGPNVDSCSSCYSSDNEDGGAKNKPQTPQIDENSNKVGLTEKPPSSPVTVASQSPEVAIVTPSAPVSSSPSPPALTLTPPAAPGTPVPGTTSPSPSTTIISTLPVPATASSNASRPTSSKQRSRHAPITQLGLQINQRGGAAASSKRYMAGSLVRAQTVSSSTSNSSSSNSAGRGKATNNGLNLVATQTKAATSGNNQSSAGAAAGTGGSTTAAPPAGAAATPNAAITVSKPSAAEREREQGGDYLIEICGRYLNIYGQGALRFIDKQWNPAKANDVHTLNFSYINFNSIVCVLGRIKLRFPHAEHYVFRETNISCLGQLNGLAELQGLSSLMIDAEGNGITLKETWRAYAIYRLSHWGLKQLNGQEVTEAEVEAANAMYVGLSDLVLWSMPEVMLQPLLARLRLDETCTASKLSPKEWLLRPDNKSLRLVVGKEALQWKKNAGGGAGTSTSMNINQGTEAGSTAMAPSVRDRGRQHFALLLENTCNAVEKLHKLETLWPSMLLDIVRNTLLDYAQLDVYLRNLMCELLK", "length": 1301, "header": "tr|Q9VZ81-1|Q9VZ81_DROME Isoform 1 of Dynein axonemal assembly factor 1 homolog OS=Drosophila melanogaster OX=7227 GN=CT33170 PE=4 SV=1 CANONICAL=Q9VZ81-1" }, "isoforms": [ { "isoform_ac": "Q9VZ81-1", "url": "https://www.uniprot.org/uniprotkb/Q9VZ81/entry#Q9VZ81-1", "sequence": { "sequence": "MAKCRGRSILNDETPTPEAACPAPGPAPAATPAAANPLPHPQQQQLQQQQNYLPQTSLLKIEPFVPSFNQRLRRRPIGRSHSTLSHNVISKRPVPQQHQQQQIQQPSELQVGQQQQLKRGYAAAAQIRQQQQQQQRNLPRGVGIQRQRSKSTSSSAASNSCRPATAAVTPNTLVGSTGGTLVSGAIVTPQPNGICRIQRLPKEREELPDRINYDKRGLTAIPIFEQEPNLRLLSLQHNLINTFHIPKEVTPPPPPVPPPAVATPRESNNNKLGEYSNGNGNKEGGRSGLRGHHPGRLTRAMTNAGGNSHRLSPKSGGSPGSGSPLTTQALAINGGTAAGRSKLAKRGYNYGQAQLTPPPALRMRYGLEKSKSFVSSSLQAMKHQQQLIQRRAMLKATRAGGVVAPGGAASNLLQSCDEGSALHNSNLSLYGGCGEEEESPSVMTSISALEQLSIKNKQLSLSASYGSIFQQLVFLDLYDNQIERIANLDGLPSLSVLLLGKNRITDIGGLSSLKDTLRVLDLHGNKLTSLGSRINCLQQLKSLNLAGNQIRQINQQDFLGLRCLRELNLKRNKLRRINGFQHLVALERLWLCHNDLHRVDDMASIARATRLLEVTIENNPVSLAGDCVSFLVSYLPLLQTLSQMPITEQVRRAALAWRQHKEQAQAAPGSSEAYHNIRREEVISNARTNWELLRSQQTVVGRPKSRLTSELAKINESNEGPAGEEGEMESEESQQPKELMDELQALIKLPPIAKDLRNPHEEDGASSEASSLGPNVDSCSSCYSSDNEDGGAKNKPQTPQIDENSNKVGLTEKPPSSPVTVASQSPEVAIVTPSAPVSSSPSPPALTLTPPAAPGTPVPGTTSPSPSTTIISTLPVPATASSNASRPTSSKQRSRHAPITQLGLQINQRGGAAASSKRYMAGSLVRAQTVSSSTSNSSSSNSAGRGKATNNGLNLVATQTKAATSGNNQSSAGAAAGTGGSTTAAPPAGAAATPNAAITVSKPSAAEREREQGGDYLIEICGRYLNIYGQGALRFIDKQWNPAKANDVHTLNFSYINFNSIVCVLGRIKLRFPHAEHYVFRETNISCLGQLNGLAELQGLSSLMIDAEGNGITLKETWRAYAIYRLSHWGLKQLNGQEVTEAEVEAANAMYVGLSDLVLWSMPEVMLQPLLARLRLDETCTASKLSPKEWLLRPDNKSLRLVVGKEALQWKKNAGGGAGTSTSMNINQGTEAGSTAMAPSVRDRGRQHFALLLENTCNAVEKLHKLETLWPSMLLDIVRNTLLDYAQLDVYLRNLMCELLK", "length": 1301, "header": "tr|Q9VZ81-1|Q9VZ81_DROME Isoform 1 of Dynein axonemal assembly factor 1 homolog OS=Drosophila melanogaster OX=7227 GN=CT33170 PE=4 SV=1 CANONICAL=Q9VZ81-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 16, "start_aa": "Thr", "end_pos": 16, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr16", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 31, "start_aa": "Thr", "end_pos": 31, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr31", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ81", "url": "https://www.uniprot.org/uniprotkb/Q9VZ81" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ81", "url": "https://www.uniprot.org/uniprotkb/Q9VZ81" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ81", "url": "https://www.uniprot.org/uniprotkb/Q9VZ81" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ81", "url": "https://www.uniprot.org/uniprotkb/Q9VZ81" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ81", "url": "https://www.uniprot.org/uniprotkb/Q9VZ81" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ81", "url": "https://www.uniprot.org/uniprotkb/Q9VZ81" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ81", "url": "https://www.uniprot.org/uniprotkb/Q9VZ81" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ81", "url": "https://www.uniprot.org/uniprotkb/Q9VZ81" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ81", "url": "https://www.uniprot.org/uniprotkb/Q9VZ81" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ81", "url": "https://www.uniprot.org/uniprotkb/Q9VZ81" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ81", "url": "https://www.uniprot.org/uniprotkb/Q9VZ81" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], 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"RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647932" }, { "id": "Q9VZ82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ82" } ] }, { "name": "CG7479", "type": "synonym", "evidence": [ { "id": "NP_647932", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647932" }, { "id": "Q9VZ82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ82" } ] }, { "name": "Dmel\\CG7479", "type": "synonym", "evidence": [ { "id": "NP_647932", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647932" }, { "id": "Q9VZ82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ82" } ] }, { "name": "Dmel_CG7479", "type": "synonym", "evidence": [ { "id": "Q9VZ82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ82" } ] }, { "name": "LARS", "type": "synonym", "evidence": [ { "id": "NP_647932", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647932" }, { "id": "Q9VZ82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ82" } ] }, { "name": "LRS", "type": "synonym", "evidence": [ { "id": "NP_647932", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647932" }, { "id": "Q9VZ82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ82" } ] }, { "name": "LeuRS-m", "type": "synonym", "evidence": [ { "id": "NP_647932", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647932" } ] }, { "name": "LeuRS", "type": "synonym", "evidence": [ { "id": "NP_647932", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647932" }, { "id": "Q9VZ82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ82" } ] }, { "name": "dLARS", "type": "synonym", "evidence": [ { "id": "NP_647932", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647932" }, { "id": "Q9VZ82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ82" } ] } ], "protein_names": [ { "name": "leucine--tRNA ligase", "type": "recommended", "evidence": [ { "id": "Q9VZ82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ82/entry#names_and_taxonomy" } ] }, { "name": "6.1.1.4", "type": "synonym", "evidence": [ { "id": "Q9VZ82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ82/entry#names_and_taxonomy" } ] }, { "name": "CG7479-PA", "type": "synonym", "evidence": [ { "id": "NP_647932", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647932" } ] }, { "name": "LeuRS-m-PA", "type": "synonym", "evidence": [ { "id": "NP_647932", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647932" } ] }, { "name": "Leucyl-tRNA synthetase, mitochondrial", "type": "synonym", "evidence": [ { "id": "NP_647932", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647932" } ] }, { "name": "Leucyl-tRNA synthetase", "type": "synonym", "evidence": [ { "id": "NP_647932", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647932" }, { "id": "Q9VZ82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ82/entry#names_and_taxonomy" } ] }, { "name": "mitochondrial leucyl-tRNA synthetase", "type": "synonym", "evidence": [ { "id": "NP_647932", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647932" } ] } ], "function": [], "disease": [ { "disease_id": "DOID:0050857", "recommended_name": { "id": "DOID:0050857", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050857", "name": "Perrault syndrome", "description": "A syndrome that is characterized by sensorineural hearing loss and ovarian failure." }, "synonyms": [ { "id": "MONDO:0009300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009300", "name": "Perrault syndrome 1", "description": "Any Perrault syndrome in which the cause of the disease is a mutation in the HSD17B4 gene." }, { "id": "MONDO:0009300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009300", "name": "HSD17B4 Perrault syndrome", "description": "" }, { "id": "MONDO:0009300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009300", "name": "Perrault syndrome 1", "description": "" }, { "id": "MONDO:0009300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009300", "name": "Perrault syndrome caused by mutation in HSD17B4", "description": "" }, { "id": "MONDO:0009300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009300", "name": "Perrault syndrome type 1", "description": "" }, { "id": "MONDO:0009300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009300", "name": "PRLTS1", "description": "" }, { "id": "MONDO:0013588", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013588", "name": "Perrault syndrome 3", "description": "Any Perrault syndrome in which the cause of the disease is a mutation in the CLPP gene." }, { "id": "MONDO:0013588", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013588", "name": "CLPP Perrault syndrome", "description": "" }, { "id": "MONDO:0013588", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013588", "name": "Perrault syndrome 3", "description": "" }, { "id": "MONDO:0013588", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013588", "name": "Perrault syndrome caused by mutation in CLPP", "description": "" }, { "id": "MONDO:0013588", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013588", "name": "Perrault syndrome type 3", "description": "" }, { "id": "MONDO:0013588", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013588", "name": "PRLTS3", "description": "" }, { "id": "MONDO:0013588", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013588", "name": "deafness, autosomal recessive 81", "description": "" }, { "id": "MONDO:0014126", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014126", "name": "Perrault syndrome 4", "description": "Any Perrault syndrome in which the cause of the disease is a mutation in the LARS2 gene." }, { "id": "MONDO:0014126", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014126", "name": "LARS2 Perrault syndrome", "description": "" }, { "id": "MONDO:0014126", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014126", "name": "Perrault syndrome 4", "description": "" }, { "id": "MONDO:0014126", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014126", "name": "Perrault syndrome caused by mutation in LARS2", "description": "" }, { "id": "MONDO:0014126", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014126", "name": "Perrault syndrome type 4", "description": "" }, { "id": "MONDO:0014126", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014126", "name": "PRLTS4", "description": "" }, { "id": "MIM:233400", "resource": "MIM", "url": "https://www.omim.org/entry/233400", "name": "Perrault syndrome 1", "description": "Perrault syndrome 1" }, { "id": "MIM:614129", "resource": "MIM", "url": "https://www.omim.org/entry/614129", "name": "Perrault syndrome 3", "description": "Perrault syndrome 3" }, { "id": "MIM:615300", "resource": "MIM", "url": "https://www.omim.org/entry/615300", "name": "Perrault syndrome 4", "description": "Perrault syndrome 4" } ], "unlinked_id_list": [], "evidence": [ { "id": "0050857", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050857" } ] }, { "disease_id": "DOID:700", "recommended_name": { "id": "DOID:700", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:700", "name": "mitochondrial metabolism 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4825853, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0027085", "url": "https://www.ensemblgenomes.org/id/FBgn0027085" } ] } } ], "crossref": [ { "id": "FB:FBgn0027085", "url": "https://alliancegenome.org/gene/FB:FBgn0027085", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0027085", "url": "https://bgee.org/?page=gene&gene_id=FBgn0027085", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00812", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00812", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0027085", "url": "https://flybase.org/reports/FBgn0027085", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "38581", "url": "https://www.ncbi.nlm.nih.gov/gene/38581", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001412", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001412", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002300", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002300", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002302", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002302", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009080", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009080", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013155", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013155", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014729", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014729", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG7479", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG7479", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GIEHACM", "url": "https://omabrowser.org/oma/group/GIEHACM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VZ82", "url": "https://www.orthodb.org/?gene=Q9VZ82", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43740", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43740", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43740:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43740:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00133", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00133", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08264", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08264", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_647932", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647932", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "11688", "url": "https://www.rhea-db.org/rhea/11688", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q9VZ82", "url": "https://www.uniprot.org/uniprotkb/Q9VZ82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VZ82-1", "url": "https://www.uniprot.org/uniprotkb/Q9VZ82-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQALRRTRPWGAVYWNSWRRLLTQSCTRNDNPELTSDVKHRIEAHWREQLSGGQFNPKDSQDKYYVLSMFPYPSGNLHMGHVRVYTIADSVARFQRMCGKNVFQPMGWDSFGLPAENAANQRGVEPASWTEQNIAQMKEQLKRLGCSFDWNHELSTCSPKYYKWTQHLFLMLHRHGLAYQNEALVNWDPVDKTVLADEQVDANGCSWRSGAKVEKKLLRQWFIRTSAYAKQLLDGLEDPTLRDWRDIINLQRHWIGECDGYAFNLLTSASGLLRVWTTHPEHLKDPHAFLVLRSNHHLSKLKGADSLSAANPFAGTTMPVVFSDEVTFPPKSDVYLAAPSFRGEDKDLWDSYGLAFTSNGKDEESLSPANWEMLRKEVLQAATRLNVGGYRVSSKLKDWLISRQRYWGTPIPIVHCQKCGAVPVPEEQLPVSLPPKDSPKEAFLCDCPKCGEKDARRETDTMDTFVDSSWYYLRYLDAQNSERIFDTALTKKFMPVDLYIGGKEHAVLHLYYARFINHFLHSCGLSPTSEPFSRLLVQGMVMGRSFRVKGSGRYVPETEVEIVNAKKNQAVLKETKEPVVMTWEKMSKSKLNGVEPSDMFNEYGTDTTRLIILADVAPTSHRNWSSATFPGILNWQKRLWLTLQDFQQAREDQTASDVVPTSEEFLAEDAKLFDARNFYVKGATFNYRHAQQLSVAISKMQGLTNSLRRTPKHVLRHGKQFERALAAQIIMLAPMAPHFASELWSKFVAIPGRLNPASQELQWSEDVLAQRWPDIDPAYNLDLSIKVNGFENCVIKVQRTHLDKVTHSDALDIAFNTESVTSYLIDKKIRTTNFVLYPGIEAILNIYVDKAKMKQKPPTTDDAEAQPQA", "length": 869, "header": "tr|Q9VZ82-1|Q9VZ82_DROME Isoform 1 of leucine--tRNA ligase OS=Drosophila melanogaster OX=7227 GN=LeuRS-m PE=1 SV=1 CANONICAL=Q9VZ82-1" }, "isoforms": [ { "isoform_ac": "Q9VZ82-1", "url": "https://www.uniprot.org/uniprotkb/Q9VZ82/entry#Q9VZ82-1", "sequence": { "sequence": "MQALRRTRPWGAVYWNSWRRLLTQSCTRNDNPELTSDVKHRIEAHWREQLSGGQFNPKDSQDKYYVLSMFPYPSGNLHMGHVRVYTIADSVARFQRMCGKNVFQPMGWDSFGLPAENAANQRGVEPASWTEQNIAQMKEQLKRLGCSFDWNHELSTCSPKYYKWTQHLFLMLHRHGLAYQNEALVNWDPVDKTVLADEQVDANGCSWRSGAKVEKKLLRQWFIRTSAYAKQLLDGLEDPTLRDWRDIINLQRHWIGECDGYAFNLLTSASGLLRVWTTHPEHLKDPHAFLVLRSNHHLSKLKGADSLSAANPFAGTTMPVVFSDEVTFPPKSDVYLAAPSFRGEDKDLWDSYGLAFTSNGKDEESLSPANWEMLRKEVLQAATRLNVGGYRVSSKLKDWLISRQRYWGTPIPIVHCQKCGAVPVPEEQLPVSLPPKDSPKEAFLCDCPKCGEKDARRETDTMDTFVDSSWYYLRYLDAQNSERIFDTALTKKFMPVDLYIGGKEHAVLHLYYARFINHFLHSCGLSPTSEPFSRLLVQGMVMGRSFRVKGSGRYVPETEVEIVNAKKNQAVLKETKEPVVMTWEKMSKSKLNGVEPSDMFNEYGTDTTRLIILADVAPTSHRNWSSATFPGILNWQKRLWLTLQDFQQAREDQTASDVVPTSEEFLAEDAKLFDARNFYVKGATFNYRHAQQLSVAISKMQGLTNSLRRTPKHVLRHGKQFERALAAQIIMLAPMAPHFASELWSKFVAIPGRLNPASQELQWSEDVLAQRWPDIDPAYNLDLSIKVNGFENCVIKVQRTHLDKVTHSDALDIAFNTESVTSYLIDKKIRTTNFVLYPGIEAILNIYVDKAKMKQKPPTTDDAEAQPQA", "length": 869, "header": "tr|Q9VZ82-1|Q9VZ82_DROME Isoform 1 of leucine--tRNA ligase OS=Drosophila melanogaster OX=7227 GN=LeuRS-m PE=1 SV=1 CANONICAL=Q9VZ82-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ82", "url": "https://www.uniprot.org/uniprotkb/Q9VZ82" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ82", "url": "https://www.uniprot.org/uniprotkb/Q9VZ82" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ82", "url": "https://www.uniprot.org/uniprotkb/Q9VZ82" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ82", "url": "https://www.uniprot.org/uniprotkb/Q9VZ82" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ82", "url": "https://www.uniprot.org/uniprotkb/Q9VZ82" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ82", "url": "https://www.uniprot.org/uniprotkb/Q9VZ82" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ82", "url": "https://www.uniprot.org/uniprotkb/Q9VZ82" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ82", "url": "https://www.uniprot.org/uniprotkb/Q9VZ82" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ82", "url": "https://www.uniprot.org/uniprotkb/Q9VZ82" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ82", "url": "https://www.uniprot.org/uniprotkb/Q9VZ82" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ82", "url": "https://www.uniprot.org/uniprotkb/Q9VZ82" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG7479", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG7479", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2R8T0-1", "protein_name": "leucine--tRNA ligase", "gene_name": "LARS2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAPWQRLRFYAFLLQRQLNGGPDVINWGRGVIPGCSRGIYSATGKWTKEYTLQTRKDVEKWWHQRIKEQASKISEADKSKPKFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGMQVINPMGWDAFGLPAENAAIERNLHPESWTQSNIRHMRKQLDRLGLCFSWDREITTCLPDYYRWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVDEHGCSWRSGAKVEQKYLRQWFIKTTAYAKAMQDTLADLPEWYGIKGMQAHWIGDCVGCHLDFALKVDGQVTEEELSAYTATPEAIYGTSHVAISPSHRLLHGCSSLKEVFQKALVPGRDCLTPVMAVNMLTQQEVPVIILAKADFEGSLDAKIGIPSTSSEDTVLAQSLGLSYSEVIETSPDGTERLSNSAEFTGMNRLDAFLALTQKARRKRVGGDVTSDKLKDWLISRQRYWGTPIPMVHCPACGPVPVPLDDLPVTLPSITSFTGKGGSPLASASEWVNCSCPRCKGAATRETDTMDTFVDSAWYYFRYTDPQNTQSPFSTALADYWMPVDLYIGGKEHAVMHLFYARFFSHFCHDQKMVKHREPFHKLLAQGLIKGQTFRLPSGQYLQREEVDLTGSVPVHVKTREKLEVTWEKMSKSKHNGVDPEDVVEQYGIDTIRLYLLFAAPPEKDILWDVKTDALPGVLRWQQRLWALATRFIEARISEKVPRPQLLSNKEKAEAKKLWEYKNSVISQVTAHFTEDLSLNSVISHLMGLSSALSQASQRVVLHSPEFEDALCALMVMAAPMAPHITSELWAGLALVPRKLCPHYAWDADVLLQAWPAVDPQFLQQPDVVQMAVLINNKACGKIPVPQQVAQDQDKVYELVLQSELGIKLLQGRSIKKAFLSPRTALINFLVQE", "length": 902 }, "evidence": [ { "id": "Q9VZ82", "url": "https://omabrowser.org/oma/group/Q9VZ82/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5ZU78-1", "protein_name": "leucine--tRNA ligase", "gene_name": "Lars2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASACQRLSFCVSPLKRQLVSGLPVILWERIIPGCSRSIYSATGKWTKEYTLQTRKDVEKWWHQQIKVQASKISEEDKLKPKFYLLSMFPYPSGKLHMGHVRVYTLSDTIARFQKMRGMQVINPMGWDAFGLPAENAAIERNLHPESWTQSNIKHMRKQLDRLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVNEYGCSWRSGAKVEKKYLRQWFIKTTAYAKAMQDALADLPEWYGIKEMQAHWIGDCVGCHLDFTLKVDGQDTGEKLTAYTATPEAIYGISHVAISPSHGLLHGCSSLKTALQKALVPGRDCLTPVMAVNMLTLQEVPVVIMAKPDLEGSLDSKIGIPSTSSEDTRLAQALGLPYSEVIETSPDGTERLSGSAEFTGMTRQDAFVALTRKARGMRVGGHVTSNKLKDWLVSRQRYWGTPIPIVHCPACGPVPVPLQDLPVTLPSITSLTGRGGSPLASALEWVNCSCPRCKGSAKRETDTMDTFVDSAWYYFRYTDPHNTHSPFSSALADFWMPVDLYIGGKEHAVMHLFYARFFSHFCHRQKMVKHREPFHKLLAQGLIKGQTFHLLSGQCLKREDIDFTGPTPVCAKTKERLEVTWEKMSKSKHNGVDPEEIVAQYGIDTIRLYILFAAPPEKDILWDVKTDALPGVLRWQQRLWSLTTRFIEARTSGTAPQPQLLNNKEKAKARSLWEYKNAVITQVTTHFTEDFALNSVVSQLMGLSGALSQASQRLVLHSPEFEDALCALLVMAAPLAPHITSELWAGLALVPSKLCDRYAWDAGVMLQAWPTVDSQFLQKPDMVQMAVLINNKACGKIPVPQHVAQDQDKVHEFVLQSELGIKLLQGRSIRKAFLSPRTALINFLVKE", "length": 902 }, "evidence": [ { "id": "RGD:1308429", "url": "https://alliancegenome.org/gene/RGD:1308429#orthology", "database": "AGR" }, { "id": "MGI:2142973", "url": "https://alliancegenome.org/gene/MGI:2142973#orthology", "database": "AGR" }, { "id": "HGNC:17095", "url": "https://alliancegenome.org/gene/HGNC:17095#orthology", "database": "AGR" }, { "id": "FB:FBgn0027085", "url": "https://alliancegenome.org/gene/FB:FBgn0027085#orthology", "database": "AGR" }, { "id": "SGD:S000004374", "url": "https://alliancegenome.org/gene/SGD:S000004374#orthology", "database": "AGR" }, { "id": "Q9VZ82", "url": "https://omabrowser.org/oma/group/Q9VZ82/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0YV38-1", "protein_name": "leucine--tRNA ligase", "gene_name": "LARS2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MDTVALRMQSVCRRFGACSTCLNRQLNGFLGLRNRTPLPSHACIRTIYSETGRWEKNYGQETRRRVENWWFPRIKEQFCRISETDKSRPKFYVLSMFPYPSGKLHMGHVRVYTISDTVARFQKMRGMQVLNPMGWDAFGLPAENAAIEHGLHPASWTQSNIQHMREQFDALGLSFTWEREITTCLPEYYKWTQYLFLKLFESGMVYQKEALVNWDPVDQTVLANEQVDDNGCSWRSGAKVEQKYLKQWFIKTTAYAKAMFDALSDLPEWYGIKEMQANWIGDCVGCSLDFLLKVNGEVTGEKLAAYTYTPEAIYGASHLYILPSHRLLHGNSSLKEVFQREFIPGKDSLTSVTAVNLLTNQEIPVVISGKTSFENYLDTKIGIPCTSAEDAAVAKNLNISFTEVIEKLPNGLEKVINSGEFTGMTRQDALKALTQQAKNKGIGGDLMSDKLRDWLISRQRYWGTPIPVIHCRTCGTVPVPYEDLPVVLPNVTTFTGKGASPLETVPEWVNCACPRCKAEARREIDTMDTFVDSAWYYLRYTDPHNTQRPFNRDLADYWMPVDLYIGGKEHAVMHLFYARFFSHFCHDLKMTKHKEPFHKLLVQGLIKNQTFRLRTTGQYLKREEIDLTGTEPVHLKSGEKVQVTWEKMSKSKHNGIDPEELMKEYGIDTIRLYILFAAPPEQDILWDTKTDAMPGVQRWQTRLWTLVTKLIEARTSETMPNPEVLSKKQKAEARRIWEQKNLVISEVTEYFTKDHLFNAAISRLMSLSNVLHQASWPLVLHSAEYEDALATLCVMVAPMAPHIASEMWKGLAHIENKLCTHHNWGADVLHQSWPKVDPEYLQPPDVVEMSVLINNKACGKVFVPQQAARNFAEVHELVLQSELGAKHLQGRTIKKAFLSPRTALINFLVQERKR", "length": 914 }, "evidence": [ { "id": "Q9VZ82", "url": "https://omabrowser.org/oma/group/Q9VZ82/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E1B768-1", "protein_name": "leucine--tRNA ligase", "gene_name": "LARS2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAPSWQRLGLYACLLKRQLNDGPDVIKWGRRVIPGWSRGIYSATGEWTKEYTLQTRKDVEKWWHQRIKDQALTVSEADKSKPKFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGMQVINPMGWDAFGLPAENAAIERNLHPESWTQSNIRHMRKQLDQLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVDEHGCSWRSGAKVEQKYLRQWFIKTTAYAKAMQDALAGLPEWYGIKGMQAHWIGNCVGCHLDFMLKVDGQVTGEKLSAYTATPEAVYGASHVAISPSHRLLHGHSPLKETFRKALVPGQDCLTPVTAVNMLTQQEVPVIILAKDDLEGSLDAKIGIPSTSLEDSALAQTLGLSYSEVIEETPDGTERLRGSAEFTGMKRQDAFLALTQKARRERVGGDVTSDKLKDWLVSRQRYWGTPIPMVHCPACGPVPVPLEDLPVTLPSITPLTGRGGSPLASASEWVNCSCPRCKGAATRETDTMDTFVDSAWYYFRYTDPQNTQSPFSAALADYWMPVDLYIGGKEHAVMHLFYARFFSHFCHDQKMVKHREPFHKLLAQGLIKGQTFRLPSGQYLRREEVDLTGSDPVHANTGEKLEVSWEKMSKSKHNGVEPEDVVEQYGRDTVRLYVLFAAPPEKDILWDVKTDALPGVLRWQQRLWALVTRFIEARTSGKAPRPQLLSDKDKAEARRLWEYKNSVISQVTAHFTEDFSLNSAISQLMGLSSALSQASQRVVLHSPEFEDALCALMVMAAPMAPHITSELWAGLALVPQKLCAHYAWNTSVLLQAWPTVDPQFLQQPEVVQMAVLINNKACGKVPVPQHVAQDQDKVHELVLQSELGVRLLQGRSIKKAFLSPRTALINFLLQE", "length": 903 }, "evidence": [ { "id": "Q9VZ82", "url": "https://omabrowser.org/oma/group/Q9VZ82/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3HWS5-1", "protein_name": "leucine--tRNA ligase", "gene_name": "Lars2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASACQRLRFYACPLTRQLVCGPPVIQWERRTIPACARSIYSATGTWTKEYTLQTRKDVENWWHRQIKEQASRISEDDKSKPKFYVLSMFPYPSGKLHMGHIRVYTLSDTIARFQKMRGMQVINPMGWDAFGLPAENAAIERNLHPESWTQSNIKYMRKQLDRLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVNEYGCSWRSGAKVEKKYLRQWFIKTTAYAKAMQDALADLPEWYGIKGMQAHWIGDCVGCHLEFTLKVDGQDTGEKLTAYTATPEAIYGISHVAISPNHRLLHGCSSLKEPLQKVLVPGRDCLTPVMAVNMLTQQEVPIVVMAKADLEGSLDSKIGIPSTSSEDTSIAQALGLPYSEVIETSPDGTERLSGSAEFTGMTRQDAFLALTQKARGMRVGGDVTSDKLKDWLISRQRYWGTPIPIVHCPACGPVPVPLQDLPVTLPSITSFTGKGGSPLASALEWVNCPCPRCKRPARRETDTMDTFVDSAWYYLRYTDPQNTHRPFSPALANFWMPVDLYIGGKEHAVMHLFYARFFSHFCHDQKMVKHREPFHKLLAQGLIKGQTFRLPSGLCLKREDIDFTGPAPVCARTKEKLEVTWEKMSKSKHNGVDPEEIVAQYGIDTVRLYILFAAPPEKDILWDVKTDALPGVLRWQQRLWSLTTRFIEARTRGSAPQPQLLNNKEETKARNLWEYKNSVITQVTTHFTEDFALNSAVSQLMGLSSALLQASDRVVLHSREFEDALCALLVMAAPMAPHITSELWAGLALVPSKLCDHYAWDAGVMLQAWPTVDSEFLQQPDVVQMAILINNKAYGKISVPQQVAQDQDKVHEFVLQSELGTRLLQGRSIKKAFLSPRTALINFLVQE", "length": 903 }, "evidence": [ { "id": "Q9VZ82", "url": "https://omabrowser.org/oma/group/Q9VZ82/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P11325-1", "protein_name": "Leucine--tRNA ligase, mitochondrial", "gene_name": "NAM2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLSRPSSRFLSTKRGPGPAVKKLIAIGEKWKQKTTRGLPKQDTLNSGSKYILCQFPYPSGALHIGHLRVYVISDSLNRFYKQKGYNVIHPMGWDAFGLPAENAAIERSINPAIWTRDNIAKMKQQMQSMLANFDWDREITTCDPEYYKFTQWIFLKLFENGLAYRKEAEINWDPVDMTVLANEQVDAQGRSWRSGAIVEKKQLKQWFLGITKFAPKLKKHLNQLKDWPSNVKQMQKNWIGESVGAELVFKVADPKFENLIVFTTRPETLFAVQYVALALDHPIVQKYCEEMPDLKEFIQKSDQLPNDTKEGFQLPNIKAVNPLTKEEVPIFAAPYVVSSYGSAPSAVMGCPGHDNRDFEFWQTNCPGEHIKTCIAPFFDDASKVTEQERQRIIDTVPFTSTDGVLTKECGEHSGVLTVVARKSIMGMLNSEGLSKSVVRYKIRDWLISRQRYWGTPIPIIHCDNCGPVPVPESDLPVKLPELEGLDTKGNPLSTIDEFVNVACPSCGSPAKRETDTMDTFIDSSWYYFRFLDPKNTSKPFDREIASKNMPVDIYIGGVEHAILHLLYSRFIAKFLGSINAWSDPAGIFEPFKKLVTQGMVQGKTYVDPDSGKFLKPDELTFVNDSPDGNTVIIKSNGKVPVVSYEKMSKSKYNGADPNECILRHGPDATRAHILFQSPIADALNWDESKIVGIERWLQKVLHLTKNILSLEKDLAISKDYKTPTDLNDAEVKFHNDFQRFLKSITESFEVNLSLNTVISDYMKLTNILESALKKGEVRNEMIVQNLQKLVTVIYPAVPSISEEAAEMINSQMEWNQYRWPEVERTTESKFKKFQIVVNGRVKFMYTADKNFLKLGRDAVIETLMNLPEGRMYLMNKKIKKFVMKFNVISFLFHK", "length": 894 }, "evidence": [ { "id": "RGD:1308429", "url": "https://alliancegenome.org/gene/RGD:1308429#orthology", "database": "AGR" }, { "id": "MGI:2142973", "url": "https://alliancegenome.org/gene/MGI:2142973#orthology", "database": "AGR" }, { "id": "HGNC:17095", "url": "https://alliancegenome.org/gene/HGNC:17095#orthology", "database": "AGR" }, { "id": "FB:FBgn0027085", "url": "https://alliancegenome.org/gene/FB:FBgn0027085#orthology", "database": "AGR" }, { "id": "SGD:S000004374", "url": "https://alliancegenome.org/gene/SGD:S000004374#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q15031-1", "protein_name": "Leucine--tRNA ligase, mitochondrial", "gene_name": "LARS2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASVWQRLGFYASLLKRQLNGGPDVIKWERRVIPGCTRSIYSATGKWTKEYTLQTRKDVEKWWHQRIKEQASKISEADKSKPKFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGMQVINPMGWDAFGLPAENAAVERNLHPQSWTQSNIKHMRKQLDRLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVDEHGCSWRSGAKVEQKYLRQWFIKTTAYAKAMQDALADLPEWYGIKGMQAHWIGDCVGCHLDFTLKVHGQATGEKLTAYTATPEAIYGTSHVAISPSHRLLHGHSSLKEALRMALVPGKDCLTPVMAVNMLTQQEVPVVILAKADLEGSLDSKIGIPSTSSEDTILAQTLGLAYSEVIETLPDGTERLSSSAEFTGMTRQDAFLALTQKARGKRVGGDVTSDKLKDWLISRQRYWGTPIPIVHCPVCGPTPVPLEDLPVTLPNIASFTGKGGPPLAMASEWVNCSCPRCKGAAKRETDTMDTFVDSAWYYFRYTDPHNPHSPFNTAVADYWMPVDLYIGGKEHAVMHLFYARFFSHFCHDQKMVKHREPFHKLLAQGLIKGQTFRLPSGQYLQREEVDLTGSVPVHAKTKEKLEVTWEKMSKSKHNGVDPEEVVEQYGIDTIRLYILFAAPPEKDILWDVKTDALPGVLRWQQRLWTLTTRFIEARASGKSPQPQLLSNKEKAEARKLWEYKNSVISQVTTHFTEDFSLNSAISQLMGLSNALSQASQSVILHSPEFEDALCALMVMAAPLAPHVTSEIWAGLALVPRKLCAHYTWDASVLLQAWPAVDPEFLQQPEVVQMAVLINNKACGKIPVPQQVARDQDKVHEFVLQSELGVRLLQGRSIKKSFLSPRTALINFLVQD", "length": 903 }, "evidence": [ { "id": "RGD:1308429", "url": "https://alliancegenome.org/gene/RGD:1308429#orthology", "database": "AGR" }, { "id": "MGI:2142973", "url": "https://alliancegenome.org/gene/MGI:2142973#orthology", "database": "AGR" }, { "id": "HGNC:17095", "url": "https://alliancegenome.org/gene/HGNC:17095#orthology", "database": "AGR" }, { "id": "FB:FBgn0027085", "url": "https://alliancegenome.org/gene/FB:FBgn0027085#orthology", "database": "AGR" }, { "id": "SGD:S000004374", "url": "https://alliancegenome.org/gene/SGD:S000004374#orthology", "database": "AGR" }, { "id": "Q9VZ82", "url": "https://omabrowser.org/oma/group/Q9VZ82/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q54ET5-1", "protein_name": "Leucine--tRNA ligase, mitochondrial", "gene_name": "mleuS", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNLYRSSLKNLKLPNINNNIKSNLVIRSYTTNINGNIKNDDDNNKFYSLSQFPYPSGALHMGHVRVYTISDCIARLKRMQGYDVIHPMGWDAFGLPAENAAIDKQVSPSEWTNLNISSMRDQLKLLNFQFDWDRELSTCNKEYYRWTQEIFLRLLKSGLAYRKSATVNWDPIDQTVLANEQVDAQGRSWRSNAIVEKKEMKQWFYKITSMADRLTDDLDQLPGWSDEIKNMQKEWIGRSYGHLIEFQSCAQKPLSNITVFTTRAETIYGVSFLAISPHHSEINQIRANLINDEKRLELDQYLKEIQEIKNKMGTQEDVENLKTFNTGLTFYQPITKKYIPLILSNFVHADYGTGAVMGVPSHNRSDYQVAKQQNLKLLPVLGIEREQQQQQQQQQQQQQLEIEEECYDYSNTGKLINSGQDTGIEFKEFIKRLEDQQLIKRQTNYRIHDWLISRQRYWGTPIPIIVCEKCGDVPVPSDQLPVELPIDIQFTGKGNLLNQLDHWKNVKCPCCGSQATRETDTMDTFVDSSWYFLRFLDSKNSQSIFSSELVNRFMPIDVYVGGIEHAILHLLYSRFITKFLKDQQLIDHSEPFKVLLAQGLVKSPTYRDSITNKPIHPSNVEFKTIKSNESGKSQQQTINKLTGNQVSVTIEKMSKSKLNGIDPKEIIDKYGSDTLKTYILFKAPPEKSLDWDTQGIEGCKKWLTRINVSIQSFLNQFDVIEGKEQHQHQQQQHQQPLPSSEFNEQQSKEVKDILFETHLTMNKVTESIDKHSFNTGIAALMELSNTLQKSSPQIKLTKEYYQSLRALTLMLFPFSPIFSQIHWKSLIDDLPQSCKSFYSENYSSFEQQSYGNSNDNDVFNQRWPKPTPSALVRDFNSLVIQFDGKTKGVESIPTSITDFSNFVQSNSKYLNRFKDKTIDQIFIGTTKTGNSINFTFKKK", "length": 940 }, "evidence": [ { "id": "Q9VZ82", "url": "https://omabrowser.org/oma/group/Q9VZ82/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8VDC0-1", "protein_name": "Probable leucine--tRNA ligase, mitochondrial", "gene_name": "Lars2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASTCQRLSFYVSPLKRQLVSRPPVILWERLIPGCSRSIYSATGKWTKEYTLQTRKDVEKWWHQQIKEQASRVSEEDKLKPKFYLLSMFPYPSGKLHMGHVRVYTLSDTIARFQKMRGMQVINPMGWDAFGLPAENAAIERNLHPESWTQSNIKHMRKQLDRLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVNEYGCSWRSGAKVEKKYLRQWFIKTTAYAKAMQDALADLPEWYGIKGMQAHWIGDCVGCHLDFTLKVDGEDTGEKLTAYTATPEAIYGISHVAISPSHGLLHGCSSVKKALQKALVPGRDCLTPVMAVSMLTLQEVPIVIMANPDLEGSLDSKIGIPSTSSEDTRLAQALGLPYSEVIEASPDGTERLSGSAEFTGMTRQDAFVALTRKARGMRVGGHVTSNKLKDWLISRQRYWGTPIPIVHCPACGPVPVPLQDLPVILPSIASLTGRGGSPLATALEWVNCSCPRCKGSAKRETDTMDTFVDSAWYYFRYTDPHNTQSPFGSALADFWMPVDLYIGGKEHAVMHLFYARFLSHFCHDQKMVKHREPFHKLLAQGLIKGQTFRLPSGQCLKKEDIDFTGPAPVCAKTKEKLEVTWEKMSKSKHNGVDPEEIVAQYGIDTIRLYILFAAPPEKDILWDVKTDALPGVLRWQQRLWSLTTRFIEARTSGTVPQPQLLNSKEKTKAQNLWEYKNAVIAQVTTHFTEDFALNSVVSQLMGLSSALSQASQRVVLHSPEFEDALCALLVMAAPLAPHVTSELWAGLTLVPSKLCDHYAWDSGVMLQAWPTVDSQFLQKPDMVQMAVLINNKACGKIPVPQHVAQDQDKVHELVLQSELGMKLLQGRSIKKAFLSPRTALINFLVQE", "length": 902 }, "evidence": [ { "id": "RGD:1308429", "url": "https://alliancegenome.org/gene/RGD:1308429#orthology", "database": "AGR" }, { "id": "MGI:2142973", "url": "https://alliancegenome.org/gene/MGI:2142973#orthology", "database": "AGR" }, { "id": "HGNC:17095", "url": "https://alliancegenome.org/gene/HGNC:17095#orthology", "database": "AGR" }, { "id": "FB:FBgn0027085", "url": "https://alliancegenome.org/gene/FB:FBgn0027085#orthology", "database": "AGR" }, { "id": "SGD:S000004374", "url": "https://alliancegenome.org/gene/SGD:S000004374#orthology", "database": "AGR" }, { "id": "Q9VZ82", "url": "https://omabrowser.org/oma/group/Q9VZ82/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9XEA0-1", "protein_name": "Leucine--tRNA ligase, chloroplastic/mitochondrial", "gene_name": "EMB2369", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSHHQILQIRSDPFVLSHCCRHTRLTSSLTLQSPLKQPFSCLPFRWRRSYRGGVRSSTTETHGSKKEALVSETATTSIELKRVYPFHEIEPKWQRYWEDNRIFRTPDDVDTSKPKFYVLDMFPYPSGAGLHVGHPLGYTATDILARLRRMQGYNVLHPMGWDAFGLPAEQYAIETGTHPKTTTLKNIDRFRLQLKSLGFSYDWDRELSTTEPDYYKWTQWIFLQLYKKGLAYQAEVPVNWCPALGTVLANEEVVDGVSERGGHPVIRKPMRQWMLKITAYADRLLEDLDELEWPESIKEMQRNWIGRSEGAELNFSILDGEGRETDKEITVYTTRPDTLFGATYMVVAPEHQLLSYFVTAEQKQQVEEYKDFASRKSDLERTELQKDKTGVFTGCYAKNPANGDAIPIWVADYVLASYGTGAIMAVPAHDTRDNEFALKYNIPIKWVVRNEANSSDDAKQVYPGLGIIENSSTLETGLDINQLSSKEAALKVIEWAERTGNGKKKVNYKLRDWLFARQRYWGEPIPILILDESGETIAISESELPLTLPELNDFTPTGTGEPPLSKAVSWVNTVDPSTGKPAKRETSTMPQWAGSCWYYLRFMDPKNPEALVDKEKEKYWSPVDVYVGGAEHAVLHLLYSRFWHKVLYDIGVVSTKEPFKCVINQGIILGEVQYTAWKDQEGNYVSADTEERLNEHQQVTIPEEKVIKSGDHFVLKEDPSIRLIPRVYKMSKSRGNVVNPDDVVLEYGADSLRLYEMFMGPFRDSKTWNTSGIEGVHRFLARTWRLVIGLPQSDGSFKDGTLVTDDEPTLEQLRTLHKCIAKVTEEIESTRFNTGISGMMEFVNAAYKWNNQPRGIIEPFVLLLSPYAPHMAEELWSRLGHPNSLAYESFPKANPDYLKNTTIVLPVQINGKTRGTIEVEEGCSEDDAFVLASQDDKLRKYLDGQSIKKRIYVPGKILNVILDRTNVKVTTK", "length": 973 }, "evidence": [ { "id": "Q9VZ82", "url": "https://omabrowser.org/oma/group/Q9VZ82/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "aminoacyl-tRNA deacylase activity", "id": "GO:0002161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002161", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ82", "url": "https://www.uniprot.org/uniprotkb/Q9VZ82" } ], "pmid": "" }, { "name": "leucine-tRNA ligase activity", "id": "GO:0004823", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004823", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ82", "url": "https://www.uniprot.org/uniprotkb/Q9VZ82" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ82", "url": "https://www.uniprot.org/uniprotkb/Q9VZ82" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "leucyl-tRNA aminoacylation", "id": "GO:0006429", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006429", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ82", "url": "https://www.uniprot.org/uniprotkb/Q9VZ82" } ], "pmid": "" }, { "name": "mitochondrial translation", "id": "GO:0032543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032543", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ82", "url": "https://www.uniprot.org/uniprotkb/Q9VZ82" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ82", "url": "https://www.uniprot.org/uniprotkb/Q9VZ82" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 623, "end_pos": 625, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "11688", "name": "", "equation": "tRNA(Leu) + L-leucine + ATP = L-leucyl-tRNA(Leu) + AMP + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VZ82-1", "Q9VQR8-1" ], "evidence": [ { "id": "11688", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/11688" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "Q9VQR8", "gene_name": "LeuRS", "activity": [ { "ec_number": "6.1.1.4", "activity": "tRNA(Leu) + L-leucine + ATP = L-leucyl-tRNA(Leu) + AMP + diphosphate.", "evidence": [ { "id": "Q9VQR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQR8" } ] }, { "ec_number": "6.1.1.4", "activity": "", "evidence": [ { "id": "Q9VQR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQR8" } ] } ] }, { "uniprot_ac": "Q9VZ82", "gene_name": "LeuRS-m", "activity": [ { "ec_number": "6.1.1.4", "activity": "tRNA(Leu) + L-leucine + ATP = L-leucyl-tRNA(Leu) + AMP + diphosphate.", "evidence": [ { "id": "Q9VZ82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ82" } ] }, { "ec_number": "6.1.1.4", "activity": "", "evidence": [ { "id": "Q9VZ82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ82" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VZ82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ82" }, { "id": "PF00133", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00133" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Aminoacyl-tRNA synthetase class Ia", "eco_id": "ECO_0000259", "start_pos": 55, "end_pos": 237, "start_aa": "Phe", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q9VZ82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ82" }, { "id": "PF08264", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08264" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding", "eco_id": "ECO_0000259", "start_pos": 691, "end_pos": 784, "start_aa": "Gln", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "6.1.1.4", "ec_name": "tRNA(Leu) + L-leucine + ATP = L-leucyl-tRNA(Leu) + AMP + diphosphate.", "evidence": [ { "id": "6.1.1.4", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.4" }, { "id": "6.1.1.4", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=6.1.1.4" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 623, "end_pos": 625 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VZ85-1", "uniprot_ac": "Q9VZ85", "uniprot_id": "Q9VZ85_DROME", "mass": { "chemical_mass": 214913.0, "monoisotopic_mass": 214913.0 }, "refseq": { "ac": "NP_001261425", "name": "Rho guanine nucleotide exchange factor at 64C, isoform B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261425" }, "gene_names": [ { "name": "RhoGEF64C", "type": "recommended", "evidence": [ { "id": "Q9VZ85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ85" } ] }, { "name": "CG13709", "type": "synonym", "evidence": [ { "id": "NP_001261425", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261425" }, { "id": "Q9VZ85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ85" } ] }, { "name": "CG13710", "type": "synonym", "evidence": [ { "id": "NP_001261425", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261425" }, { "id": "Q9VZ85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ85" } ] }, { "name": "CG32239", "type": "synonym", "evidence": [ { "id": "NP_001261425", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261425" }, { "id": "Q9VZ85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ85" } ] }, { "name": "Dmel\\CG32239", "type": "synonym", "evidence": [ { "id": "NP_001261425", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261425" }, { "id": "Q9VZ85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ85" } ] }, { "name": "Dmel_CG32239", "type": "synonym", "evidence": [ { "id": "Q9VZ85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ85" } ] }, { "name": "EP(3)3035", "type": "synonym", "evidence": [ { "id": "NP_001261425", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261425" }, { "id": "Q9VZ85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ85" } ] }, { "name": "EP3035", "type": "synonym", "evidence": [ { "id": "NP_001261425", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261425" }, { "id": "Q9VZ85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ85" } ] }, { "name": "GEF(64C)", "type": "synonym", "evidence": [ { "id": "NP_001261425", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261425" }, { "id": "Q9VZ85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ85" } ] }, { "name": "GEF64C", "type": "synonym", "evidence": [ { "id": "NP_001261425", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261425" }, { "id": "Q9VZ85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ85" } ] }, { "name": "GEF", "type": "synonym", "evidence": [ { "id": "NP_001261425", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261425" }, { "id": "Q9VZ85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ85" } ] }, { "name": "Gef64C", "type": "synonym", "evidence": [ { "id": "NP_001261425", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261425" }, { "id": "Q9VZ85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ85" } ] }, { "name": "RhoGEF64C", "type": "synonym", "evidence": [ { "id": "NP_001261425", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261425" } ] }, { "name": "RhoGEF64", "type": "synonym", "evidence": [ { "id": "NP_001261425", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261425" }, { "id": "Q9VZ85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ85" } ] }, { "name": "RhoGEF", "type": "synonym", "evidence": [ { "id": "NP_001261425", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261425" }, { "id": "Q9VZ85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ85" } ] }, { "name": "RhoGef64C", "type": "synonym", "evidence": [ { "id": "NP_001261425", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261425" }, { "id": "Q9VZ85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ85" } ] } ], "protein_names": [ { "name": "CG32239-PB", "type": "synonym", "evidence": [ { "id": "NP_001261425", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261425" } ] }, { "name": "Rho guanine nucleotide exchange factor at 64C, isoform A", "type": "synonym", "evidence": [ { "id": "Q9VZ85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ85/entry#names_and_taxonomy" } ] }, { "name": "Rho guanine nucleotide exchange factor at 64C, 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"length": 1984, "header": "tr|Q9VZ85-1|Q9VZ85_DROME Isoform 1 of Rho guanine nucleotide exchange factor at 64C, isoform B OS=Drosophila melanogaster OX=7227 GN=RhoGEF64C PE=4 SV=2 CANONICAL=Q9VZ85-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1144, "start_aa": "Thr", "end_pos": 1144, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1144", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1285, "start_aa": "Thr", "end_pos": 1285, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1285", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 455, "start_aa": "Thr", "end_pos": 455, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr455", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 489, "start_aa": "Thr", "end_pos": 489, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr489", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 545, "start_aa": "Thr", "end_pos": 545, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr545", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 574, "start_aa": "Thr", "end_pos": 574, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr574", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": 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An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, 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Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ85", "url": "https://www.uniprot.org/uniprotkb/Q9VZ85" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ85", "url": "https://www.uniprot.org/uniprotkb/Q9VZ85" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila 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"https://www.uniprot.org/uniprotkb/Q9VZ97" } ] }, { "name": "Dmel\\CG32238", "type": "synonym", "evidence": [ { "id": "NP_729025", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_729025" }, { "id": "Q9VZ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ97" } ] }, { "name": "Dmel_CG32238", "type": "synonym", "evidence": [ { "id": "Q9VZ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ97" } ] }, { "name": "TTLL1B", "type": "synonym", "evidence": [ { "id": "NP_729025", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_729025" } ] }, { "name": "TTLL1", "type": "synonym", "evidence": [ { "id": "NP_729025", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_729025" }, { "id": "Q9VZ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ97" } ] } ], "protein_names": [ { "name": "Polyglutamylase complex subunit TTLL1", "type": "recommended", "evidence": [ { "id": "Q9VZ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ97/entry#names_and_taxonomy" } ] }, { "name": "CG32238-PA", "type": "synonym", "evidence": [ { "id": "NP_729025", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_729025" } ] }, { "name": "TTLL1B-PA", "type": "synonym", "evidence": [ { "id": "NP_729025", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_729025" } ] }, { "name": "Tubulin polyglutamylase TTLL1", "type": "synonym", "evidence": [ { "id": "Q9VZ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ97/entry#names_and_taxonomy" } ] }, { "name": "Tubulin polyglutamylase complex subunit 3", "type": "synonym", "evidence": [ { "id": "Q9VZ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ97/entry#names_and_taxonomy" } ] }, { "name": "Tubulin--tyrosine ligase-like protein 1", "type": "synonym", "evidence": [ { "id": "Q9VZ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZ97/entry#names_and_taxonomy" } ] }, { "name": "tubulin tyrosine ligase-like 1B", "type": "synonym", "evidence": [ { "id": "NP_729025", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_729025" } ] } ], "function": [], "disease": [ { "disease_id": "DOID:9562", "recommended_name": { "id": "DOID:9562", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9562", "name": "primary ciliary dyskinesia", "description": "A ciliopathy that is characterized by impaired function of the cilia lining the respiratory tract (lower and upper, sinuses, Eustachian tube, middle ear) and fallopian tube." }, "synonyms": [ { "id": "DOID:9562", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9562", "name": "ciliary motility disorder", "description": "" }, { "id": "DOID:9562", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9562", "name": "immotile ciliary syndrome", "description": "" }, { "id": "MONDO:0009484", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009484", "name": "primary ciliary dyskinesia 1", "description": "Any primary ciliary dyskinesia in which the cause of the disease is a mutation in the DNAI1 gene." }, { "id": "MONDO:0009484", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009484", "name": "CILD1", "description": "" }, { "id": "MONDO:0009484", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009484", "name": "DNAI1 primary ciliary dyskinesia", "description": "" }, { "id": "MONDO:0009484", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009484", "name": "ciliary dyskinesia, primary, type 1", "description": "" }, { "id": "MONDO:0009484", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009484", "name": "primary ciliary dyskinesia 1", "description": "" }, { "id": "MONDO:0009484", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009484", "name": "primary ciliary dyskinesia caused by mutation in DNAI1", "description": "" }, { "id": "MONDO:0009484", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009484", "name": "primary ciliary dyskinesia type 1", "description": "" }, { "id": "MONDO:0009484", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009484", "name": "PCD", "description": "" }, { "id": "MONDO:0009484", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009484", "name": "ciliary dyskinesia, primary, 1", "description": "" }, { "id": "MIM:244400", "resource": "MIM", "url": "https://www.omim.org/entry/244400", "name": "Kartagener syndrome", "description": "Kartagener syndrome" } ], "unlinked_id_list": [], "evidence": [ { "id": "9562", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9562" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VZ97", "url": "https://www.uniprot.org/uniprotkb/Q9VZ97" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "TTLL1B", "url": "https://www.uniprot.org/uniprotkb/Q9VZ97", "locus": { "chromosome": "3L", "start_pos": 4650305, "end_pos": 4648276, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0052238", "url": "https://www.ensemblgenomes.org/id/FBgn0052238" } ] } } ], "crossref": [ { "id": "FB:FBgn0052238", "url": "https://alliancegenome.org/gene/FB:FBgn0052238", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0052238", "url": "https://bgee.org/?page=gene&gene_id=FBgn0052238", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0052238", "url": "https://flybase.org/reports/FBgn0052238", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "326203", "url": "https://www.ncbi.nlm.nih.gov/gene/326203", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004344", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004344", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG32238", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG32238", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DWNFYWS", "url": "https://omabrowser.org/oma/group/DWNFYWS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VZ97", "url": "https://www.orthodb.org/?gene=Q9VZ97", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12241", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12241", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12241:SF31", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12241:SF31", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03133", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03133", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_729025", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_729025", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "60148", "url": "https://www.rhea-db.org/rhea/60148", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q9VZ97", "url": "https://www.uniprot.org/uniprotkb/Q9VZ97", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VZ97-1", "url": "https://www.uniprot.org/uniprotkb/Q9VZ97-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVVWDMSQWTQAWRIDSLHPTVRSSGTRTTTSGTIMYGRTSVGANQSVTNGNSNSGANSGGGASGGAQGHDKLKIGFCTDLDKSVLVNNFEKRGWHQVNGDDDWHFYWAGVQTCRNIFSVDSGYRMHDNQMINHFPNHYELSRKDLLVKNIKRYRKDLERDGNPLAEKTESNNSSGTRYLYLDFVPTTFVLPADYNMFVEEYRKFPLSTWIMKPCGKSQGAGIFLINKLSKLKKWSREAKGPFHPQIAKESYVISRYIDNPLLIGGKKFDLRLYVLVASFRPLKAYLFKQGFCRFCTVKYDTSVTELDNMYVHLTNVSVQKHGGEYNTLHGGKWSVQNLALYLEGTRGKEVTDRLFGAISWLIVHSLRAVAPVMASDRHCFECYGYDIIIDNALKPWLVEVNASPSLTSTTVNDRILKYKLIDNILSVVLPPDGVPDVRWNKVPSADALGNFELLIDEELAAQDEQHQNSSSNTHSKTSKMGSRWK", "length": 487, "header": "tr|Q9VZ97-1|Q9VZ97_DROME Isoform 1 of Polyglutamylase complex subunit TTLL1 OS=Drosophila melanogaster OX=7227 GN=TTLL1B PE=3 SV=1 CANONICAL=Q9VZ97-1" }, "isoforms": [ { "isoform_ac": "Q9VZ97-1", "url": "https://www.uniprot.org/uniprotkb/Q9VZ97/entry#Q9VZ97-1", "sequence": { "sequence": "MAVVWDMSQWTQAWRIDSLHPTVRSSGTRTTTSGTIMYGRTSVGANQSVTNGNSNSGANSGGGASGGAQGHDKLKIGFCTDLDKSVLVNNFEKRGWHQVNGDDDWHFYWAGVQTCRNIFSVDSGYRMHDNQMINHFPNHYELSRKDLLVKNIKRYRKDLERDGNPLAEKTESNNSSGTRYLYLDFVPTTFVLPADYNMFVEEYRKFPLSTWIMKPCGKSQGAGIFLINKLSKLKKWSREAKGPFHPQIAKESYVISRYIDNPLLIGGKKFDLRLYVLVASFRPLKAYLFKQGFCRFCTVKYDTSVTELDNMYVHLTNVSVQKHGGEYNTLHGGKWSVQNLALYLEGTRGKEVTDRLFGAISWLIVHSLRAVAPVMASDRHCFECYGYDIIIDNALKPWLVEVNASPSLTSTTVNDRILKYKLIDNILSVVLPPDGVPDVRWNKVPSADALGNFELLIDEELAAQDEQHQNSSSNTHSKTSKMGSRWK", "length": 487, "header": "tr|Q9VZ97-1|Q9VZ97_DROME Isoform 1 of Polyglutamylase complex subunit TTLL1 OS=Drosophila melanogaster OX=7227 GN=TTLL1B PE=3 SV=1 CANONICAL=Q9VZ97-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ97", "url": "https://www.uniprot.org/uniprotkb/Q9VZ97" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ97", "url": "https://www.uniprot.org/uniprotkb/Q9VZ97" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ97", "url": "https://www.uniprot.org/uniprotkb/Q9VZ97" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ97", "url": "https://www.uniprot.org/uniprotkb/Q9VZ97" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ97", "url": "https://www.uniprot.org/uniprotkb/Q9VZ97" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ97", "url": "https://www.uniprot.org/uniprotkb/Q9VZ97" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ97", "url": "https://www.uniprot.org/uniprotkb/Q9VZ97" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ97", "url": "https://www.uniprot.org/uniprotkb/Q9VZ97" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ97", "url": "https://www.uniprot.org/uniprotkb/Q9VZ97" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ97", "url": "https://www.uniprot.org/uniprotkb/Q9VZ97" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ97", "url": "https://www.uniprot.org/uniprotkb/Q9VZ97" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG32238", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG32238", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1P2G8-1", "protein_name": "Polyglutamylase complex subunit TTLL1", "gene_name": "ttll1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAGKVKWVTDIEKSVLINNFEKRGWIQVTDSEDWNFYWMSIQTIRTVFSVDTGYRLTDDQMVNHFPNHYELTRKDLMIKNIKRYRRELEKENSALAEKDDSGKYIYLDFVPVTFMLPADYNLFVEEFRKSPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSRTSTFVAANSGKEAYVISLYIDNPLLIGGKKFDLRLYVLVTTYRPLKCYMYKLGFCRFCTVKYTPSTSELDNMFVHLTNVAIQKHGDDYNHVHGGKWTVSNLRLYLESTRGPDVTNHLFDQIHWIIVQSLKAVAPVMNNDKHCFECYGYDIIIDDRLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIVTPNAEIPDCRWNRSLPKEALGHYQVLYDEEQALSESTERDLRSRSGHSLGSKSTRQSGVRPFPATWK", "length": 423 }, "evidence": [ { "id": "RGD:1309124", "url": "https://alliancegenome.org/gene/RGD:1309124#orthology", "database": "AGR" }, { "id": "MGI:2443047", "url": 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"MAGKVKWVTDIEKSVLINNFEKRGWIQVAENEDWNFYWMSVQTIRNVFSVETGYRLSDDQIVNHFPNHYELTRKDLMVKNIKRYRKELEKEGSPLAEKDENGKYIYLDFVPVTFMLPADYNLFVEEFRKNPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSSKEAYVISLYINNPLLIGGKKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHLTNVAIQKHGDDYNHIHGGKWTVSNLRLYLESTRGKEVTNKLFDEIHWIIVQSLKAVAPVMNNDKHCFECYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIAVPNGEIPDCKWNKSPPKEVLGNYEVLYDEEMAQSDGSDRDLRSRSGQSTGTKGNRGRDSGKPVLTTWK", "length": 423 }, "evidence": [ { "id": "Q9VZ97", "url": "https://omabrowser.org/oma/group/Q9VZ97/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O95922-1", "protein_name": "Polyglutamylase complex subunit TTLL1", "gene_name": "TTLL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGKVKWVTDIEKSVLINNFEKRGWVQVTENEDWNFYWMSVQTIRNVFSVEAGYRLSDDQIVNHFPNHYELTRKDLMVKNIKRYRKELEKEGSPLAEKDENGKYLYLDFVPVTYMLPADYNLFVEEFRKSPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSNKEAYVISLYINNPLLIGGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHLTNVAIQKHGEDYNHIHGGKWTVSNLRLYLESTRGKEVTSKLFDEIHWIIVQSLKAVAPVMNNDKHCFECYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIAVPNGEIPDCKWNKSPPKEVLGNYEILYDEELAQGDGADRELRSRQGQSLGPRAGRSRDSGRAVLTTWK", "length": 423 }, "evidence": [ { "id": "RGD:1309124", "url": "https://alliancegenome.org/gene/RGD:1309124#orthology", "database": "AGR" }, { "id": "MGI:2443047", "url": "https://alliancegenome.org/gene/MGI:2443047#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1326", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1326#orthology", "database": "AGR" }, { "id": "HGNC:1312", "url": "https://alliancegenome.org/gene/HGNC:1312#orthology", "database": "AGR" }, { "id": "FB:FBgn0052238", "url": 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"Bovine" }, { "uniprot_canonical_ac": "Q5PPI9-1", "protein_name": "Polyglutamylase complex subunit TTLL1", "gene_name": "Ttll1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGRVKWVTDIEKSVLINNFEKRGWVQVTENEDWNFYWMSVQTIRNVFSVETGYRLSDDQIVNHFPNHYELTRKDLMVKNIKRYRKELEKEGSPLAEKDENGKYLYLDFVPVTYMLPADYNLFVEEFRKSPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSTKEAYVISLYINNPLLIGGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHLTNVAIQKHGEDYNHIHGGKWTVNNLRLYLESTRGREVTSKLFDEIHWIIVQSLKAVAPVMNNDKHCFECYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIAVPNGEIPDCKWNKSPPKEVLGNYEILYDEELAQGDGAERELRSRPGQPVGPRTGRSRDSGRNVLTTWK", "length": 423 }, "evidence": [ { "id": "RGD:1309124", "url": "https://alliancegenome.org/gene/RGD:1309124#orthology", "database": "AGR" }, { "id": "MGI:2443047", "url": "https://alliancegenome.org/gene/MGI:2443047#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1326", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1326#orthology", "database": "AGR" }, { "id": "HGNC:1312", "url": "https://alliancegenome.org/gene/HGNC:1312#orthology", "database": "AGR" }, { "id": "FB:FBgn0052238", "url": "https://alliancegenome.org/gene/FB:FBgn0052238#orthology", "database": "AGR" }, { "id": "Q9VZ97", "url": "https://omabrowser.org/oma/group/Q9VZ97/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q91V51-1", "protein_name": "Polyglutamylase complex subunit TTLL1", "gene_name": "Ttll1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGRVKWVTDIEKSVLINNFEKRGWIQVTENEDWNFYWMSVQTIRNVFSVETGYRLSDDQIVNHFPNHYELTRKDLMVKNIKRYRKELEKEGSPLAEKDENGKYLYLDFVPVTYMLPADYNLFVEEFRKSPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSTKEAYVISVYINNPLLIGGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHLTNVAIQKHGEDYNHIHGGKWTVNNLRLYLESTRGREVTSKLFDEIHWIIVQSLKAVAPVMNNDKHCFECYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIAVPNGEIPDCKWNKSPPKEVLGNYEILYDEELAQGDGAERELRNRPGQPVGPRAGRSRDSGRSVLTTWK", "length": 423 }, "evidence": [ { "id": "RGD:1309124", "url": "https://alliancegenome.org/gene/RGD:1309124#orthology", "database": "AGR" }, { "id": "MGI:2443047", "url": "https://alliancegenome.org/gene/MGI:2443047#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1326", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1326#orthology", "database": "AGR" }, { "id": "HGNC:1312", "url": "https://alliancegenome.org/gene/HGNC:1312#orthology", "database": "AGR" }, { "id": "FB:FBgn0052238", "url": "https://alliancegenome.org/gene/FB:FBgn0052238#orthology", "database": "AGR" }, { "id": "Q9VZ97", "url": "https://omabrowser.org/oma/group/Q9VZ97/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VX74-1", "protein_name": "Polyglutamylase complex subunit TTLL1", "gene_name": "TTLL1A", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSTRRQTSPLRNLRQKCGGSCTSDDDLPEVKLITQPINGLHYIRNRLRPPKSRNGIYYSTDWDKSALVSNFQKRGWLQVPSFNGEWNFYWACTQNCRYIFGIDHPYRMRSDQVINHFPNSIELSRKDLLIKNIKRYRKDLERRGDPLAQSHPPDTKLGIGGTRYKHLDIIPMTFVLPSDYQMFVEVFHRNPASTWIVKPCSKSQGVGIYLVNKLSKLKKFAYDARTFYPQINRDTCVISKYIDNPLLIGGKKFDLRLFVLVTTFNPLKAYLYKEGFCRFCTEKYDETEIDNVFMHLTNVSIQKTNQEYNSIHGGKWPLQNLWLYLDSLRGEGVSDMLWSRITATIRHSLDAVAPVMANDRHCFEVYGYDIIIDNNLKPWLIEINTSPSMHSTTTNDRMLKSRLIDNVLDVVVPPNCMPNEHWDKTPNPELLKNFTVLMPISPCKPKEQVPVRRKGRLSKKKKSKSTTASSGICSFTPPPAEGETKIKRSNKVVKRL", "length": 496 }, "evidence": [ { "id": "RGD:1309124", "url": "https://alliancegenome.org/gene/RGD:1309124#orthology", "database": "AGR" }, { "id": "MGI:2443047", "url": "https://alliancegenome.org/gene/MGI:2443047#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1326", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1326#orthology", "database": "AGR" }, { "id": "HGNC:1312", "url": "https://alliancegenome.org/gene/HGNC:1312#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "tubulin-glutamic acid ligase activity", "id": "GO:0070740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070740", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ97", "url": "https://www.uniprot.org/uniprotkb/Q9VZ97" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ97", "url": "https://www.uniprot.org/uniprotkb/Q9VZ97" } ], "pmid": "" }, { "name": "tubulin binding", "id": "GO:0015631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015631", "evidence": [ { "database": "UniProtKB", "id": "Q9VZ97", "url": "https://www.uniprot.org/uniprotkb/Q9VZ97" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "microtubule", "id": "GO:0005874", "url": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VZE9-1", "uniprot_ac": "Q9VZE9", "uniprot_id": "Q9VZE9_DROME", "mass": { "chemical_mass": 9387.0, "monoisotopic_mass": 9387.0 }, "refseq": { "ac": "NP_001097499", "name": "vacuolar H[+] ATPase M9.7 subunit a, isoform B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097499" }, "gene_names": [ { "name": "VhaM9.7-a", "type": "recommended", "evidence": [ { 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"https://www.uniprot.org/uniprotkb/Q9VZE9" } ] }, { "name": "VhaM9.7-a", "type": "synonym", "evidence": [ { "id": "NP_001097499", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097499" } ] }, { "name": "vhaM9.7-1", "type": "synonym", "evidence": [ { "id": "NP_001097499", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097499" }, { "id": "Q9VZE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZE9" } ] } ], "protein_names": [ { "name": "V-type proton ATPase subunit", "type": "recommended", "evidence": [ { "id": "Q9VZE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZE9/entry#names_and_taxonomy" } ] }, { "name": "CG1268-PB", "type": "synonym", "evidence": [ { "id": "NP_001097499", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097499" } ] }, { "name": "VhaM9.7-a-PB", "type": "synonym", "evidence": [ { "id": "NP_001097499", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097499" } ] }, { "name": "vacuolar H[+] ATPase M9.7 subunit a, isoform B", "type": "synonym", "evidence": [ { "id": "NP_001097499", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097499" } ] }, { "name": "vacuolar H[+] ATPase subunit M9.7-a", "type": "synonym", "evidence": [ { "id": "NP_001097499", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097499" } ] } ], "function": [ { "annotation": "Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.", "evidence": [ { "database": "UniProtKB", "id": "Q9VZE9", "url": "https://www.uniprot.org/uniprotkb/Q9VZE9#function" }, { "database": "UniProtKB", "id": "PIRNR038097", "url": "https://www.uniprot.org/uniprotkb/PIRNR038097#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VZE9", "url": "https://www.uniprot.org/uniprotkb/Q9VZE9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "VhaM9.7-a", "url": "https://www.uniprot.org/uniprotkb/Q9VZE9", "locus": { "chromosome": "3L", "start_pos": 4263464, "end_pos": 4262705, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0035521", "url": "https://www.ensemblgenomes.org/id/FBgn0035521" } ] } } ], "crossref": [ { "id": "FB:FBgn0035521", "url": "https://alliancegenome.org/gene/FB:FBgn0035521", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0035521", "url": "https://bgee.org/?page=gene&gene_id=FBgn0035521", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0035521", "url": "https://flybase.org/reports/FBgn0035521", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "38521", "url": "https://www.ncbi.nlm.nih.gov/gene/38521", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008389", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008389", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017385", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017385", "database": "InterPro", "categories": [ "Protein 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"https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q9VZE9", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-DME-1222556", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1222556", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-77387", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-77387", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-917977", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-917977", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-9639288", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9639288", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-983712", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-983712", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001097499", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097499", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VZE9", "url": "https://www.uniprot.org/uniprotkb/Q9VZE9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VZE9-1", "url": "https://www.uniprot.org/uniprotkb/Q9VZE9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGAAFFPVLFFTALWGGVGIAMPIMTPKGPHQNLIRCILMLTAACCWLFWLCCYMAQMNPLIGPKLKRDVVAMIGRSWNNPIVAG", "length": 85, "header": "tr|Q9VZE9-1|Q9VZE9_DROME Isoform 1 of V-type proton ATPase subunit OS=Drosophila melanogaster OX=7227 GN=VhaM9.7-a PE=3 SV=1 CANONICAL=Q9VZE9-1" }, "isoforms": [ { "isoform_ac": "Q9VZE9-1", "url": "https://www.uniprot.org/uniprotkb/Q9VZE9/entry#Q9VZE9-1", "sequence": { "sequence": "MGAAFFPVLFFTALWGGVGIAMPIMTPKGPHQNLIRCILMLTAACCWLFWLCCYMAQMNPLIGPKLKRDVVAMIGRSWNNPIVAG", "length": 85, "header": "tr|Q9VZE9-1|Q9VZE9_DROME Isoform 1 of V-type proton ATPase subunit OS=Drosophila melanogaster OX=7227 GN=VhaM9.7-a PE=3 SV=1 CANONICAL=Q9VZE9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VZE9", "url": "https://www.uniprot.org/uniprotkb/Q9VZE9" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VZE9", "url": "https://www.uniprot.org/uniprotkb/Q9VZE9" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZE9", "url": "https://www.uniprot.org/uniprotkb/Q9VZE9" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZE9", "url": "https://www.uniprot.org/uniprotkb/Q9VZE9" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VZE9", "url": "https://www.uniprot.org/uniprotkb/Q9VZE9" } ], "reference": [ { "type": "PubMed", "id": 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Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VZE9", "url": "https://www.uniprot.org/uniprotkb/Q9VZE9" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VZE9", "url": "https://www.uniprot.org/uniprotkb/Q9VZE9" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi 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"https://www.uniprot.org/uniprotkb/Q9VZF0" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VZF0", "url": "https://www.uniprot.org/uniprotkb/Q9VZF0" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZF0", "url": "https://www.uniprot.org/uniprotkb/Q9VZF0" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", 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Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VZF0", "url": "https://www.uniprot.org/uniprotkb/Q9VZF0" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VZF0", "url": "https://www.uniprot.org/uniprotkb/Q9VZF0" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi 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A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, 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Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VZG8", "url": "https://www.uniprot.org/uniprotkb/Q9VZG8" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VZG8", "url": "https://www.uniprot.org/uniprotkb/Q9VZG8" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi 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"00000000000000000000.0000000.00000001000000.1000000.0100000000.110100100001111011.10000.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_reported_with_glycan", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VZJ3", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ3" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VZJ3", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ3" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZJ3", "url": 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"sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 12 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VZJ8-1", "uniprot_ac": "Q9VZJ8", "uniprot_id": "Q9VZJ8_DROME", "mass": { "chemical_mass": 59641.0, "monoisotopic_mass": 59641.0 }, "refseq": { "ac": "NP_001261391", "name": "uncharacterized protein, isoform E", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261391" }, "gene_names": [ { "name": "Dmel\\CG11594", "type": "recommended", "evidence": [ { "id": "Q9VZJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ8" } ] }, { "name": "CG11594", "type": "synonym", "evidence": [ { "id": "NP_001261391", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261391" }, { "id": "Q9VZJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ8" } ] }, { "name": "Dmel\\CG11594", "type": "synonym", "evidence": [ { "id": "NP_001261391", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261391" } ] }, { "name": "Dmel_CG11594", "type": "synonym", "evidence": [ { "id": "Q9VZJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ8" } ] } ], "protein_names": [ { "name": "FGGY carbohydrate kinase domain-containing protein", "type": "recommended", "evidence": [ { "id": "Q9VZJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ8/entry#names_and_taxonomy" } ] }, { "name": "CG11594-PE", "type": "synonym", "evidence": [ { "id": "NP_001261391", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261391" } ] }, { "name": "uncharacterized protein, isoform E", "type": "synonym", "evidence": [ { "id": "NP_001261391", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261391" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VZJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG11594", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ8", "locus": { "chromosome": "3L", "start_pos": 4022700, "end_pos": 4026011, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0035484", "url": "https://www.ensemblgenomes.org/id/FBgn0035484" } ] } } ], "crossref": [ { "id": "FB:FBgn0035484", "url": "https://alliancegenome.org/gene/FB:FBgn0035484", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0035484", "url": "https://bgee.org/?page=gene&gene_id=FBgn0035484", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07782", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07782", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0035484", "url": "https://flybase.org/reports/FBgn0035484", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "38473", "url": "https://www.ncbi.nlm.nih.gov/gene/38473", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000577", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000577", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018484", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018484", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018485", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018485", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG11594", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG11594", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HKAMWHE", "url": "https://omabrowser.org/oma/group/HKAMWHE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VZJ8", "url": "https://www.orthodb.org/?gene=Q9VZJ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43435", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43435", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43435:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43435:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00370", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00370", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02782", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02782", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001261391", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261391", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VZJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VZJ8-1", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSGPFFVGVDVGTGSARAALVACDGRVLEQAVQTIQTWNPEPGYYNQSSDNIWQSICQVVKKVIGGVDKSKVKGIGFDATCSLVVLGPQGSPLTVSKSGEAEQNIILWMDHRAEQETQEINAFKHSLLKYVGGQVSLEMEVPKLLWLKRNLSQTFGNIWRVFDLPDFLTWRATGVDTRSLCSVVCKWNYDAANGSWNKEFLKQADLEELTQNNFEKLGSDVQPPGRTVGKGLTAKAAGELGLSAGTVVSTSLIDAHAGALGMFGCRSKESKGADDVQGKMALIAGTSTCHMSITRKACFAQGVWGPYQDAIIPGYFLNEGGQSIAGHLLDHVLKSHESYAELKSQLGEDKFIYQHLNKLLPELAAARGLSQVGCLTQDVHVWPDLHGNRSPIADPTLRGVITGLDMTRGTESLAIKYLAFVQALAYGTRHIIENLYQYGRAPFQTLLFCGGLAKNPLYVQCHADICNLPALIPDEQEMVLVGAAALGAAASGHFDSLESASKSMGGTGQLVKPNAETLEFHNRKYKVFLQLLENQRQYRRIMQADTK", "length": 548, "header": "tr|Q9VZJ8-1|Q9VZJ8_DROME Isoform 1 of FGGY carbohydrate kinase domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG11594 PE=1 SV=1 CANONICAL=Q9VZJ8-1" }, "isoforms": [ { "isoform_ac": "Q9VZJ8-1", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ8/entry#Q9VZJ8-1", "sequence": { "sequence": "MSSGPFFVGVDVGTGSARAALVACDGRVLEQAVQTIQTWNPEPGYYNQSSDNIWQSICQVVKKVIGGVDKSKVKGIGFDATCSLVVLGPQGSPLTVSKSGEAEQNIILWMDHRAEQETQEINAFKHSLLKYVGGQVSLEMEVPKLLWLKRNLSQTFGNIWRVFDLPDFLTWRATGVDTRSLCSVVCKWNYDAANGSWNKEFLKQADLEELTQNNFEKLGSDVQPPGRTVGKGLTAKAAGELGLSAGTVVSTSLIDAHAGALGMFGCRSKESKGADDVQGKMALIAGTSTCHMSITRKACFAQGVWGPYQDAIIPGYFLNEGGQSIAGHLLDHVLKSHESYAELKSQLGEDKFIYQHLNKLLPELAAARGLSQVGCLTQDVHVWPDLHGNRSPIADPTLRGVITGLDMTRGTESLAIKYLAFVQALAYGTRHIIENLYQYGRAPFQTLLFCGGLAKNPLYVQCHADICNLPALIPDEQEMVLVGAAALGAAASGHFDSLESASKSMGGTGQLVKPNAETLEFHNRKYKVFLQLLENQRQYRRIMQADTK", "length": 548, "header": "tr|Q9VZJ8-1|Q9VZJ8_DROME Isoform 1 of FGGY carbohydrate kinase domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG11594 PE=1 SV=1 CANONICAL=Q9VZJ8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VZJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ8" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VZJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ8" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ8" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ8" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VZJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ8" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VZJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ8" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VZJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ8" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ8" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ8" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VZJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ8" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VZJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ8" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG11594", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG11594", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A2AJL3-1", "protein_name": "FGGY carbohydrate kinase domain-containing protein", "gene_name": "Fggy", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMSGRDQEPSRYYVGIDVGTGSVRAALVDQRGLLLAFAEQPIKKWEPQFNHHEQSSEDIWAACCLVTKEVVQGIDAHRIRGLGFDATCSLVVLDKEFHPLPVNHEGDSSRNVIMWLDHRAVSQVHRINETKHRVLQYVGGVMSVEMQAPKLLWLKENLREICWDKAGHFFDLPDFLSWKATGVTARSLCSLVCKWTYSAEKGWDDSFWKMIGLEDLIDDNYSKIGNLVLLPGAALGIGLTPEAARELGLPSGIAVAASLIDAHAGGLGVIGADVRGHGLTCEGQPVTSRLAVICGTSSCHMGISKDPVFVPGVWGPYYSAMVPGFWLNEGGQSVTGKLIDHMVQGHPAFPELQAKATARCQSIYAYLNSHLDLIKKAQPVGFLTVDLHVWPDFHGNRSPLADLTLKGMVTGLTLSQDLDDLAILYLATVQAIAFGTRFIIETMEAAGHSLSTLFLCGGLSKNPLFVQMHADITGMPVVLSQEVESVLVGAAILGACASGDFTSVQEAMARMSKVGKVVFPEHADKKYYDKKYQVFLRMVEHQKEYSAIMNGS", "length": 552 }, "evidence": [ { "id": "MGI:1922828", "url": "https://alliancegenome.org/gene/MGI:1922828#orthology", "database": "AGR" }, { "id": "HGNC:25610", "url": "https://alliancegenome.org/gene/HGNC:25610#orthology", "database": "AGR" }, { "id": "FB:FBgn0035484", "url": "https://alliancegenome.org/gene/FB:FBgn0035484#orthology", "database": "AGR" }, { "id": "RGD:1359429", "url": "https://alliancegenome.org/gene/RGD:1359429#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-2461", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-2461#orthology", "database": "AGR" }, { "id": "SGD:S000002516", "url": "https://alliancegenome.org/gene/SGD:S000002516#orthology", "database": "AGR" }, { "id": "SGD:S000005193", "url": "https://alliancegenome.org/gene/SGD:S000005193#orthology", "database": "AGR" }, { "id": "Q9VZJ8", "url": "https://omabrowser.org/oma/group/Q9VZJ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E1BNF8-1", "protein_name": "FGGY carbohydrate kinase domain-containing protein", "gene_name": "FGGY", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPGGNEPRSYYVGMDVGTGSVRAALVDQRGTLLAFADQPINQWEPQFNHHEQSSEDIWAACCVVSKKVVQGVNLHQIRGLGFDATCSLVVLDKQFRPLPVNPEGDSRRNIIMWLDHRAVSQVHRINETKHSVLQYVGGVMSVEMQAPKLLWLKENLRETCWDKAGHFFDLPDFLSWKATGVTARSLCSLVCKWTYSAEKGWDDSFWKMVGLEDLVTDNYSKIGNQVLPPGASLGSGLTPEAAKDLGLPPGIAVAASLIDAHAGGLGVIGADVKGHGLACEGQPVTSRLAVICGTSSCHMGISKNPIFVPGVWGPYFSAMVPGFWLNEGGQSVTGKLIDHMVQGHAAFPELQAKATARGQSVYAYLNSHLDLIKKAQPVGFLTVDLHVWPDFHGNRSPLADLTLKGMVTGLKLSQDLDDLAILYLATVQAIAFGTRLIIEAMESAGHSISTLFLCGGLSKNPLFVQMHADITGLPVVLSQEVESVLVGAAVLGACASGDFASVQEAMAKMSKVGKVVFPRHEDKRYYDKKYQVFLKLVEHQKEYAAIMKGD", "length": 550 }, "evidence": [ { "id": "Q9VZJ8", "url": "https://omabrowser.org/oma/group/Q9VZJ8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1LSP9-1", "protein_name": "FGGY carbohydrate kinase domain-containing protein", "gene_name": "Fggy", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDIQTHVLTHMQQVLPLAEPLPSPVHGRGTMMSGGDQEPDHYYVGIDVGTGSVRAALVDQRGVLLAFAEQPIKKWEPQFNHHEQSSEDIWAACCRVTKEIVQGIDAHRIRGLGFDATCSLVVLDKEFHPLPVNREGDSSRNIIMWLDHRAVSQVHRINETKHSVLQYVGGVMSVEMQAPKLLWLKENLREICWDKAGHFFDLPDFLSWKATGVTARSLCSLVCKWTYSAEKGWDDSFWKMIGLEDLIGDNYNKIGNLVLPPGASLGSGLIPEAARELGLPSGIAVAASLIDAHAGGLGVIGADVRGHGLTCEGQPVTSRLAVICGTSSCHMGISKDPIFVPGVWGPYFSAMVPGFWLNEGGQSVTGKLIDHMVQSHPAFPELQAKATARCQSIYAYLNSHLDLIKKAQPVGFLTVDLHVWPDFHGNRSPLADLTLKGMVTGLTLSRDLDDLAVLYLATIQAIAFGTRFIIETMEAAGHSLSTLFLCGGLSKNPLFVQMHADITGMPVVLSQEVESVLVGAAILGACASGDFASVQEAMARMSKVGKVVFPERADKKYYDKKYQVFLRMVEHQKEYSAIMNGS", "length": 582 }, "evidence": [ { "id": "MGI:1922828", "url": "https://alliancegenome.org/gene/MGI:1922828#orthology", "database": "AGR" }, { "id": "HGNC:25610", "url": "https://alliancegenome.org/gene/HGNC:25610#orthology", "database": "AGR" }, { "id": "FB:FBgn0035484", "url": "https://alliancegenome.org/gene/FB:FBgn0035484#orthology", "database": "AGR" }, { "id": "RGD:1359429", "url": "https://alliancegenome.org/gene/RGD:1359429#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-2461", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-2461#orthology", "database": "AGR" }, { "id": "SGD:S000002516", "url": "https://alliancegenome.org/gene/SGD:S000002516#orthology", "database": "AGR" }, { "id": "Q9VZJ8", "url": "https://omabrowser.org/oma/group/Q9VZJ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F4JQ90-1", "protein_name": "FGGY carbohydrate kinase domain-containing protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MTTAELNPFPSRSVFLGVDVGTGSARAGLFDDNGKLLGSATSPIQIWKDGDCIEQSSTDIWHAVCAAVKSACSLANVSDVEVKGIGFAATCSLVAVDAEGSPVTVSWSGDSRRNIIVWMDHRAVKQAERINSFNSPVLQYCGGGVSPEMEPPKLLWVKENLKESWSMVYKWMDLSDWLSYRATGDDTRSLCTTVCKWTYLGHAHMHQMTEKASRDMEACGWDDEFWEEIGLGDLVDGHHAKIGRSVAFPGHPLGNGLTATAAKELGLLAGTPVGTSLIDAHAGGVGVMESKLESDSLTKESDVDTLCSRMVLVCGTSTCHMAVSREKLFIPGVWGPFWSAMVPEYWLTEGGQSATGALLDHIIENHVASPRLANRAASQKVSVFELLNNILKTMAEDTSSPFISALTSDMHILPDFHGNRSPVADPNSKGVIFGMSLDTSEKQLALLYLATIQGIAYGTRHIVEHCNTHGHKIDTLLACGGLSKNPLFIQEHADIVGCPIILPRESESVLLGAAILGAVAGKNYPSLHDAMKALNAAGQVVHPSSDPKIKKYHDAKYRIFRNLYEQQLSHRSIIAEALA", "length": 579 }, "evidence": [ { "id": "Q9VZJ8", "url": "https://omabrowser.org/oma/group/Q9VZJ8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P53583-1", "protein_name": "Protein MPA43", "gene_name": "MPA43", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MNSSLQVGIGIDVGSSSARIGVYNYYNDALLEMAQEPVPYYQDSSKKSWKFWQKSTEIIKALQKCLQKLNIREYEVKSCGVSATCSLAIFERDRTSNMLIPYPNEDNVIFWMDSSAVNECQWLNMQCPQQLLDYLGGKFVPEMGVPKLKYFLDEYSHLRDKHFHIFDLHQYIAYELSRLYEWNIEGLLGRENLNGIGNDGEVSGWSSSFYKNIINLPSNVSIGTTSLVANKHISTTVVRSCIDSYASWFAVASPHLETSLFMIAGTSSCYMYGTTISDTRIPGVWGPFDTILDNRGDFSVYAAGQSCTGKLIEHLFESHPCARKILKDGADIYQVLEQTIRDIEKNNGLSIHILTKDMFFYGDYEGNRTPFADPRIKGSFIGESTDTSMLNLTYKYICILEFLSFQTKLIIDTFQNENSNIHIKELRISGSQAKNERLLSLISLVNNGVAIIKPKENVDMMGIKGAYVLAKSAKEKKQLADVITERDISNDSEKFESLAEYRLGNDSILLRKLLCVKYHIHLDMAKQQKRYHKLVDEVFQHL", "length": 542 }, "evidence": [ { "id": "MGI:1922828", "url": "https://alliancegenome.org/gene/MGI:1922828#orthology", "database": "AGR" }, { "id": "HGNC:25610", "url": "https://alliancegenome.org/gene/HGNC:25610#orthology", "database": "AGR" }, { "id": "FB:FBgn0035484", "url": "https://alliancegenome.org/gene/FB:FBgn0035484#orthology", "database": "AGR" }, { "id": "SGD:S000005193", "url": "https://alliancegenome.org/gene/SGD:S000005193#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q04585-1", "protein_name": "D-ribulokinase YDR109C", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MKSRKRQNNMQNETREPAVLSSQETSISRISPQDPEAKFYVGVDVGTGSARACVIDQSGNMLSLAEKPIKREQLISNFITQSSREIWNAVCYCVRTVVEESGVDPERVRGIGFDATCSLVVVSATNFEEIAVGPDFTNNDQNIILWMDHRAMKETEEINSSGDKCLKYVGGQMSVEMEIPKIKWLKNNLEAGIFQDCKFFDLPDYLTFKATGKENRSFCSAVCKQGFLPVGVEGSDIGWSKEFLNSIGLSELTKNDFERLGGSLREKKNFLTAGECISPLDKKAACQLGLTEHCVVSSGIIDAYAGWVGTVAAKPESAVKGLAETENYKKDFNGAIGRLAAVAGTSTCHILLSKNPIFVHGVWGPYRDVLARGFWAAEGGQSCTGVLLDHLITTHPAFTELSHMANLAGVSKFEYLNKILETLVEKRKVRSVISLAKHLFFYGDYHGNRSPIADPNMRACIIGQSMDNSIEDLAVMYLSACEFISQQTRQIIEVMLKSGHEINAIFMSGGQCRNSLLMRLLADCTGLPIVIPRYVDAAVVFGSALLGAAASEDFDYTREKRTLKGQKSSQTKTERFNDSYSSIQKLSMEDRNSTNGFVSPHNLQLSTPSAPAKINNYSLPICTQQPLDKTSEESSKDASLTVGQESLGEGRYNGTSFLWKVMQELTGNARIVNPNEKTHPDRILLDTKYQIFLDMIETQRKYRRMVDKVEGSFSR", "length": 715 }, "evidence": [ { "id": "MGI:1922828", "url": "https://alliancegenome.org/gene/MGI:1922828#orthology", "database": "AGR" }, { "id": "HGNC:25610", "url": "https://alliancegenome.org/gene/HGNC:25610#orthology", "database": "AGR" }, { "id": "FB:FBgn0035484", "url": "https://alliancegenome.org/gene/FB:FBgn0035484#orthology", "database": "AGR" }, { "id": "RGD:1359429", "url": "https://alliancegenome.org/gene/RGD:1359429#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-2461", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-2461#orthology", "database": "AGR" }, { "id": "SGD:S000002516", "url": "https://alliancegenome.org/gene/SGD:S000002516#orthology", "database": "AGR" }, { "id": "Q9VZJ8", "url": "https://omabrowser.org/oma/group/Q9VZJ8/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q6NUW9-1", "protein_name": "FGGY carbohydrate kinase domain-containing protein", "gene_name": "fggy", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGSWYYVGVDVGSASVRAALVSPDGQLRRTAEEPIAVHEPCVDHYEQSSTEIWSKCCQTVKRVTEGVDAACVRGIGFDGTCSLVVLDQQFRPLAVNLAGVCDRNVVMWMDHRAAAQASRITACRHTLLQRVGGVMSPEIQPPKLLWLKENLPDSCWTRAAHFFDLPDFLSWKATGSLSRSLCTLVCKWTYSASEGWDDTFWSAIGLEDLIEDSYARIGSQVCCPGAAVGRGLTAAAAADLGLNEGTAVGASLIDAHAGGIGVLGADVSGLHLPCEHQPLTARMALICGTSSCHMAVSREPLLVPGVWGPYLSAMLPGLWLNEGGQSATGKLLDHVVKGHAAFRQLEEQAEHSGRHIYTQLNLHLQQMSTDATHLEQLTTHLHIWPDFHGNRSPLADQTARGTVVGLSLSQTLDDLALLYLATLQALALGSRHIIAAMTEAGHDITTLFLCGGLSKNTLFVQTHANTTGLPVVLPAEREAVLLGAAVIGACASSDCTSIPEAMRKMSRVGRVVRPNPELQSFYRRKYSVFLRLYQHQKECVSLMED", "length": 545 }, "evidence": [ { "id": "MGI:1922828", "url": "https://alliancegenome.org/gene/MGI:1922828#orthology", "database": "AGR" }, { "id": "HGNC:25610", "url": "https://alliancegenome.org/gene/HGNC:25610#orthology", "database": "AGR" }, { "id": "FB:FBgn0035484", "url": "https://alliancegenome.org/gene/FB:FBgn0035484#orthology", "database": "AGR" }, { "id": "RGD:1359429", "url": 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"MSGGEQKPERYYVGVDVGTGSVRAALVDQSGVLLAFADQPIKNWEPQFNHHEQSSEDIWAACCVVTKKVVQGIDLNQIRGLGFDATCSLVVLDKQFHPLPVNQEGDSHRNVIMWLDHRAVSQVNRINETKHSVLQYVGGVMSVEMQAPKLLWLKENLREICWDKAGHFFDLPDFLSWKATGVTARSLCSLVCKWTYSAEKGWDDSFWKMIGLEDFVADNYSKIGNQVLPPGASLGNGLTPEAARDLGLLPGIAVAASLIDAHAGGLGVIGADVRGHGLICEGQPVTSRLAVICGTSSCHMGISKDPIFVPGVWGPYFSAMVPGFWLNEGGQSVTGKLIDHMVQGHAAFPELQVKATARCQSIYAYLNSHLDLIKKAQPVGFLTVDLHVWPDFHGNRSPLADLTLKGMVTGLKLSQDLDDLAILYLATVQAIALGTRFIIEAMEAAGHSISTLFLCGGLSKNPLFVQMHADITGMPVVLSQEVESVLVGAAVLGACASGDFASVQEAMAKMSKVGKVVFPRLQDKKYYDKKYQVFLKLVEHQKEYLAIMNDD", "length": 551 }, "evidence": [ { "id": "MGI:1922828", "url": "https://alliancegenome.org/gene/MGI:1922828#orthology", "database": "AGR" }, { "id": "HGNC:25610", "url": "https://alliancegenome.org/gene/HGNC:25610#orthology", "database": "AGR" }, { "id": "FB:FBgn0035484", "url": "https://alliancegenome.org/gene/FB:FBgn0035484#orthology", "database": "AGR" }, { "id": "RGD:1359429", "url": "https://alliancegenome.org/gene/RGD:1359429#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-2461", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-2461#orthology", "database": "AGR" }, { "id": "SGD:S000002516", "url": "https://alliancegenome.org/gene/SGD:S000002516#orthology", "database": "AGR" }, { "id": "SGD:S000005193", "url": "https://alliancegenome.org/gene/SGD:S000005193#orthology", "database": "AGR" }, { "id": "Q9VZJ8", "url": "https://omabrowser.org/oma/group/Q9VZJ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9VZJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "response to endoplasmic reticulum stress", "id": "GO:0034976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034976", "evidence": [ { "database": "UniProtKB", "id": "Q9VZJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ8" } ], "pmid": "" }, { "name": "pentose metabolic process", "id": "GO:0019321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019321", "evidence": [ { "database": "UniProtKB", "id": "Q9VZJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "D-ribulokinase activity", "id": "GO:0019150", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019150", "evidence": [ { "database": "UniProtKB", "id": "Q9VZJ8", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 151, "end_pos": 153, "annotation": "n_glycosylation_sequon" }, { "start_pos": 194, "end_pos": 196, "annotation": "n_glycosylation_sequon" }, { "start_pos": 389, "end_pos": 391, "annotation": "n_glycosylation_sequon" }, { "start_pos": 47, "end_pos": 49, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VZJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ8" }, { "id": "PF02782", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02782" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Carbohydrate kinase FGGY C-terminal", "eco_id": "ECO_0000259", "start_pos": 281, "end_pos": 491, "start_aa": "Met", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q9VZJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZJ8" }, { "id": "PF00370", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00370" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Carbohydrate 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"NP_647846", "name": "uncharacterized protein, isoform B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647846" }, "gene_names": [ { "name": "Dmel\\CG14985", "type": "recommended", "evidence": [ { "id": "Q9VZK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZK1" } ] }, { "name": "CG14985", "type": "synonym", "evidence": [ { "id": "NP_647846", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647846" }, { "id": "Q9VZK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZK1" } ] }, { "name": "Dmel\\CG14985", "type": "synonym", "evidence": [ { "id": "NP_647846", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647846" } ] }, { "name": "Dmel_CG14985", "type": "synonym", "evidence": [ { "id": "Q9VZK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZK1" } ] } ], "protein_names": [ { "name": "MIT domain-containing protein", "type": "recommended", "evidence": [ { "id": "Q9VZK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZK1/entry#names_and_taxonomy" } ] }, { "name": "CG14985-PB", "type": "synonym", "evidence": [ { "id": "NP_647846", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647846" } ] }, { "name": "uncharacterized protein, isoform B", "type": "synonym", "evidence": [ { "id": "NP_647846", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647846" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VZK1", "url": "https://www.uniprot.org/uniprotkb/Q9VZK1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG14985", "url": "https://www.uniprot.org/uniprotkb/Q9VZK1", "locus": { "chromosome": "3L", "start_pos": 4006626, "end_pos": 4003474, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0035482", "url": "https://www.ensemblgenomes.org/id/FBgn0035482" } ] } } ], "crossref": [ { "id": "FB:FBgn0035482", "url": "https://alliancegenome.org/gene/FB:FBgn0035482", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0035482", "url": "https://bgee.org/?page=gene&gene_id=FBgn0035482", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02683", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02683", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd02685", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02685", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0035482", "url": "https://flybase.org/reports/FBgn0035482", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "38470", "url": "https://www.ncbi.nlm.nih.gov/gene/38470", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007330", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007330", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032341", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032341", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038113", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038113", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052817", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052817", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "FYKASNP", "url": "https://omabrowser.org/oma/group/FYKASNP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VZK1", "url": "https://www.orthodb.org/?gene=Q9VZK1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21222", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21222", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21222:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21222:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04212", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04212", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16565", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16565", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_647846", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647846", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VZK1", "url": "https://www.uniprot.org/uniprotkb/Q9VZK1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VZK1-1", "url": "https://www.uniprot.org/uniprotkb/Q9VZK1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSALNAKELLIRAVECDQVGRILEAQTLYTEGIGQLMQFVNGEPDEAKRKGFLTRIKEYMDRADAIKARINGKLMLGEVVSHVSIDENDTGFDYDQLFGKYMDDKTVEIMLEEPYMTQNYQYQNLIRFLELAATNCPNLKYFRLITKEYKDAKNPDQQETNLGQIKGDLERRNVTVYIKYEDSLHDRKIYLSNGYIIKIGRGLHFYKPANPMYSIGLVNYKFRKCLQTDVDIWRNSSAAS", "length": 241, "header": "tr|Q9VZK1-1|Q9VZK1_DROME Isoform 1 of MIT domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG14985 PE=1 SV=3 CANONICAL=Q9VZK1-1" }, "isoforms": [ { "isoform_ac": "Q9VZK1-1", "url": "https://www.uniprot.org/uniprotkb/Q9VZK1/entry#Q9VZK1-1", "sequence": { "sequence": "MSSALNAKELLIRAVECDQVGRILEAQTLYTEGIGQLMQFVNGEPDEAKRKGFLTRIKEYMDRADAIKARINGKLMLGEVVSHVSIDENDTGFDYDQLFGKYMDDKTVEIMLEEPYMTQNYQYQNLIRFLELAATNCPNLKYFRLITKEYKDAKNPDQQETNLGQIKGDLERRNVTVYIKYEDSLHDRKIYLSNGYIIKIGRGLHFYKPANPMYSIGLVNYKFRKCLQTDVDIWRNSSAAS", "length": 241, "header": "tr|Q9VZK1-1|Q9VZK1_DROME Isoform 1 of MIT domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG14985 PE=1 SV=3 CANONICAL=Q9VZK1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VZK1", "url": "https://www.uniprot.org/uniprotkb/Q9VZK1" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VZK1", "url": "https://www.uniprot.org/uniprotkb/Q9VZK1" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZK1", "url": "https://www.uniprot.org/uniprotkb/Q9VZK1" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZK1", "url": "https://www.uniprot.org/uniprotkb/Q9VZK1" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VZK1", "url": "https://www.uniprot.org/uniprotkb/Q9VZK1" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VZK1", "url": "https://www.uniprot.org/uniprotkb/Q9VZK1" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VZK1", "url": "https://www.uniprot.org/uniprotkb/Q9VZK1" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZK1", "url": "https://www.uniprot.org/uniprotkb/Q9VZK1" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZK1", "url": "https://www.uniprot.org/uniprotkb/Q9VZK1" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VZK1", "url": "https://www.uniprot.org/uniprotkb/Q9VZK1" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VZK1", "url": "https://www.uniprot.org/uniprotkb/Q9VZK1" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0AB40E5J3-1", "protein_name": "MIT domain-containing protein 1", "gene_name": "mitd1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAQDLLPGVESSAVSVLKRAVQLDNCSRFQEALVCYQEGIQLLLDVLKAVKDEAKKMHYREKIKGYMERAEQIKEHTTKLKEEGKYHEQIKIADSSTGYSYESLFKPYITDGLTEVWVEDPYVRHVHQLYNFLRFCEMLLKCPSTVKTIHLLTSQDEDSSTQQSSALAEMKQSLLSKDICLDIQYSSTIHDREIRFNNGWIIKIGRGLDYFKKPKGRFSVGYCDYDLRECHETTVDIFHTKHTKKT", "length": 246 }, "evidence": [ { "id": "HGNC:25207", "url": "https://alliancegenome.org/gene/HGNC:25207#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-923", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-923#orthology", "database": "AGR" }, { "id": "MGI:1916278", "url": "https://alliancegenome.org/gene/MGI:1916278#orthology", "database": "AGR" }, { "id": "RGD:1307700", "url": "https://alliancegenome.org/gene/RGD:1307700#orthology", "database": "AGR" }, { "id": "FB:FBgn0035482", "url": "https://alliancegenome.org/gene/FB:FBgn0035482#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E1BGA2-1", "protein_name": "MIT domain-containing protein 1", "gene_name": "MITD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSRSSLAQDPGSTAALTVLKRALDLESESRGPQALVCYQEGIDLLLQVLKGTKDETKKRNLRKIISDHMDRAEHLKKRLDQEKEAGKYHKQIKIEENATGFSYESLFQEYLSETVTEVWIEDPYIRHTHQLYNFLRFCEMLVKRPCKVKTIHLLTSLDEGTGKDQHSGLEEIKQSLRNHGVSLELEYSSSIHDREIRFNNGWIIKIGRGLDYFKKPQSRFSLGYCDFDLRPCHETTVDIFHNKHTKKI", "length": 248 }, "evidence": [ { "id": "Q9VZK1", "url": "https://omabrowser.org/oma/group/Q9VZK1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1P5I2-1", "protein_name": "Microtubule interacting and trafficking domain containing 1", "gene_name": "MITD1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSRAGGDGTTALERAGAETVKRAVELDLASRFQESLVCYQEGIDLLLQVVKGTKDEAKKQRYRQKISEYMTRAEDIKKHIEKEKQDGKYHKQIKIEENATGFGYEKLFQEYLTEIVSEVWVEDPYIRNVHQLYNFLRFCEMLVKGPCKVRTIHLLTSYDEGNGRNQQTSGLEEIKQSLRNHGITLNVAFSSSIHDREIRFNNGWMIKIGRGLDYFKKPQGRFSIGYCDFDLRPCHETTVDVFHTKHTKKM", "length": 250 }, "evidence": [ { "id": "Q9VZK1", "url": "https://omabrowser.org/oma/group/Q9VZK1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1STE3-1", "protein_name": "MIT domain-containing protein 1", "gene_name": "MITD1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAKSGLGPEAGSAAAVTVIKRALELESESRYPQALVCYQEGIDLLLQVLKGTKDETKRCTLRKRISEYMDRAENIKKYLDQEKEAGKYHKQIKIEENATGFSYESLFQEYLSETVTEVWIEDPYIRHTHQLYNFLRFCEMLVKRPCKVKTIHLLTSSEEGIGKEQQSSGLQEIKESLRNHGVLLDLEYSSSIHDREIRFNNGWMIKIGRGLDYFKKPQGRFSLGYCDFDLRPCHETTVDIFHNKHTKKI", "length": 249 }, "evidence": [ { "id": "Q9VZK1", "url": "https://omabrowser.org/oma/group/Q9VZK1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3I701-1", "protein_name": "MIT domain-containing protein 1", "gene_name": "Mitd1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAKSSLGQDSDSTAAVAVLKRAVELDAESRYQQALVCYQEGIDMLLQVLKGTRDSSKRCVLRTKISDYMDRAENIKKYLDQEKEDGKYHKQIKIEENATGFSYETLFKEYLHETVTEVWIEDPYIRQTHQLYNFLRFCEMLIKKPCKIRTIHLLTSVDEGFGNAQQSSGLEEIKQSLRSHGVLLEINYSSSIHDREIRFNTGWMFKIGRGLDYFKRPQGRFSLGYCDLDLRPCHETTVDIFHNKHTKKI", "length": 249 }, "evidence": [ { "id": "Q9VZK1", "url": "https://omabrowser.org/oma/group/Q9VZK1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5I0J5-1", "protein_name": "MIT domain-containing protein 1", "gene_name": "Mitd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKSSLGQDSDSTAAVAVLKRAVELDAESRYQQALVCYQEGIDMLLQVLKGTKESSKRSTLRTKISGYMDRAENIKKYLDQEKEDGKYHKQIKIEENATGFSYESLFREYLQETVTEVWIEDPYIRQTHQLYNFLRFCEMLIKKPCKVRTIHLLTSGDEGFGNTQQSSGLEEIKQSLRSHGVVLEINYSSSIHDREIRFNNGWMIKIGRGLDYFKKPQGRFSLGYCDLDLRPCHETTVDIFHNKHTKKI", "length": 249 }, "evidence": [ { "id": "HGNC:25207", "url": "https://alliancegenome.org/gene/HGNC:25207#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-923", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-923#orthology", "database": "AGR" }, { "id": "MGI:1916278", "url": "https://alliancegenome.org/gene/MGI:1916278#orthology", "database": "AGR" }, { "id": "RGD:1307700", "url": "https://alliancegenome.org/gene/RGD:1307700#orthology", "database": "AGR" }, { "id": "FB:FBgn0035482", "url": "https://alliancegenome.org/gene/FB:FBgn0035482#orthology", "database": "AGR" }, { "id": "Q9VZK1", "url": "https://omabrowser.org/oma/group/Q9VZK1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8MLV2-1", "protein_name": "MITD1 C-terminal phospholipase D-like domain-containing protein", "gene_name": "Dmel\\CG30398", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTTSPNVAEVDDGELPKLEAIISALKCEQTGHIMEAILLYEESIFKLSQMADAEPSRRQLCGKYLKMYEARAKQLRDQVKGHLHTSRMLDHITIEQGARGRSYQRLFGPYLDDAVREAHLNEPHLTEPPHFRNLLNFFEVLVKNCRYLKYIRLTTRPDATAPKNQLQMLQQMQSDLAGGNIQMNFQMDDSLHDRKIVLSSGVVIKIGRGLHYFEPMEGSYSLGLCDFDFRKCLATEVDIWKCRPFARRLKDTQEGEDRPEAHGYSSD", "length": 267 }, "evidence": [ { "id": "HGNC:25207", "url": "https://alliancegenome.org/gene/HGNC:25207#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-923", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-923#orthology", "database": "AGR" }, { "id": "MGI:1916278", "url": "https://alliancegenome.org/gene/MGI:1916278#orthology", "database": "AGR" }, { "id": "RGD:1307700", "url": "https://alliancegenome.org/gene/RGD:1307700#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8VDV8-1", "protein_name": "MIT domain-containing protein 1", "gene_name": "Mitd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKSSLGQDSDSTAAVAVLKRAVELDAESRYQQALVCYQEGIDMLLQVLKGTKESSKRCVLRTKISGYMDRAENIKKYLDQEKEDGKYHKQIKIEENATGFSYESLFREYLHETVTEVWIEDPYIRQTHQLYNFLRFCEMLIKKPCKVRTIHLLTSGYEGLGNTQQSSGLEEIKQSLGSHGVVLEINYSSSIHDREIRFNNGWMIKIGRGLDYFKKPQGRFSLGYYDLDLRPCHETTVDIFHNKHTKKI", "length": 249 }, "evidence": [ { "id": "HGNC:25207", "url": "https://alliancegenome.org/gene/HGNC:25207#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-923", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-923#orthology", "database": "AGR" }, { "id": "MGI:1916278", "url": "https://alliancegenome.org/gene/MGI:1916278#orthology", "database": "AGR" }, { "id": "RGD:1307700", "url": "https://alliancegenome.org/gene/RGD:1307700#orthology", "database": "AGR" }, { "id": "FB:FBgn0035482", "url": "https://alliancegenome.org/gene/FB:FBgn0035482#orthology", "database": "AGR" }, { "id": "Q9VZK1", "url": "https://omabrowser.org/oma/group/Q9VZK1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WV92-1", "protein_name": "MIT domain-containing protein 1", "gene_name": "MITD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKSGLRQDPQSTAAATVLKRAVELDSESRYPQALVCYQEGIDLLLQVLKGTKDNTKRCNLREKISKYMDRAENIKKYLDQEKEDGKYHKQIKIEENATGFSYESLFREYLNETVTEVWIEDPYIRHTHQLYNFLRFCEMLIKRPCKVKTIHLLTSLDEGIEQVQQSRGLQEIEESLRSHGVLLEVQYSSSIHDREIRFNNGWMIKIGRGLDYFKKPQSRFSLGYCDFDLRPCHETTVDIFHKKHTKNI", "length": 249 }, "evidence": [ { "id": "HGNC:25207", "url": "https://alliancegenome.org/gene/HGNC:25207#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-923", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-923#orthology", "database": "AGR" }, { "id": "MGI:1916278", "url": "https://alliancegenome.org/gene/MGI:1916278#orthology", "database": "AGR" }, { "id": "RGD:1307700", "url": "https://alliancegenome.org/gene/RGD:1307700#orthology", "database": "AGR" }, { "id": "FB:FBgn0035482", "url": "https://alliancegenome.org/gene/FB:FBgn0035482#orthology", "database": "AGR" }, { "id": "Q9VZK1", "url": "https://omabrowser.org/oma/group/Q9VZK1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "Q9VZK1", "url": "https://www.uniprot.org/uniprotkb/Q9VZK1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" }, { "start_pos": 236, "end_pos": 238, "annotation": "n_glycosylation_sequon" }, { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9VZK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZK1" }, { "id": "SM00745", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00745" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MIT", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 77, "start_aa": "Met", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 174, "end_pos": 176 }, { "start_pos": 236, "end_pos": 238 }, { "start_pos": 89, "end_pos": 91 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9VZK5-1", "uniprot_ac": "Q9VZK5", "uniprot_id": "Q9VZK5_DROME", "mass": { "chemical_mass": 19244.0, "monoisotopic_mass": 19244.0 }, "refseq": { "ac": "NP_647843", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647843" }, "gene_names": [ { "name": "Dmel\\CG14983", "type": "recommended", "evidence": [ { "id": "Q9VZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZK5" } ] }, { "name": "CG14983", "type": "synonym", "evidence": [ { "id": "NP_647843", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647843" }, { "id": "Q9VZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZK5" } ] }, { "name": "Dmel\\CG14983", "type": "synonym", "evidence": [ { "id": "NP_647843", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647843" } ] }, { "name": "Dmel_CG14983", "type": "synonym", "evidence": [ { "id": "Q9VZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZK5" } ] } ], "protein_names": [ { "name": "RING-type domain-containing protein", "type": "recommended", "evidence": [ { "id": "Q9VZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZK5/entry#names_and_taxonomy" } ] }, { "name": "CG14983-PA", "type": "synonym", "evidence": [ { "id": "NP_647843", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647843" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_647843", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647843" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VZK5", "url": "https://www.uniprot.org/uniprotkb/Q9VZK5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG14983", "url": "https://www.uniprot.org/uniprotkb/Q9VZK5", "locus": { "chromosome": "3L", "start_pos": 3948699, "end_pos": 3949305, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0035479", "url": "https://www.ensemblgenomes.org/id/FBgn0035479" } ] } } ], "crossref": [ { "id": "FB:FBgn0035479", "url": "https://alliancegenome.org/gene/FB:FBgn0035479", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0035479", "url": "https://bgee.org/?page=gene&gene_id=FBgn0035479", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0035479", "url": "https://flybase.org/reports/FBgn0035479", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "38466", "url": "https://www.ncbi.nlm.nih.gov/gene/38466", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037381", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037381", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG14983", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG14983", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CSICDLK", "url": "https://omabrowser.org/oma/group/CSICDLK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VZK5", "url": "https://www.orthodb.org/?gene=Q9VZK5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16047", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16047", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16047:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16047:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13639", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13639", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_647843", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647843", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VZK5", "url": "https://www.uniprot.org/uniprotkb/Q9VZK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VZK5-1", "url": "https://www.uniprot.org/uniprotkb/Q9VZK5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLHLPKIVDLLKELQEQEKEIQEIILEESFASPEQRLAQLESVTSRMHLYHSRRGNILMSLQQELGKYEYFTLLVRHIAQTHSYLKSLNKALDFLYKVNICSICDLKCEPHGRHSMVSLRCGHLFGRHCINNVLRESSRCPTCSRRARHHEVRRIYGLKFYPL", "length": 163, "header": "tr|Q9VZK5-1|Q9VZK5_DROME Isoform 1 of RING-type domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG14983 PE=4 SV=1 CANONICAL=Q9VZK5-1" }, "isoforms": [ { "isoform_ac": "Q9VZK5-1", "url": "https://www.uniprot.org/uniprotkb/Q9VZK5/entry#Q9VZK5-1", "sequence": { "sequence": "MLHLPKIVDLLKELQEQEKEIQEIILEESFASPEQRLAQLESVTSRMHLYHSRRGNILMSLQQELGKYEYFTLLVRHIAQTHSYLKSLNKALDFLYKVNICSICDLKCEPHGRHSMVSLRCGHLFGRHCINNVLRESSRCPTCSRRARHHEVRRIYGLKFYPL", "length": 163, "header": "tr|Q9VZK5-1|Q9VZK5_DROME Isoform 1 of RING-type domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG14983 PE=4 SV=1 CANONICAL=Q9VZK5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VZK5", "url": "https://www.uniprot.org/uniprotkb/Q9VZK5" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VZK5", "url": "https://www.uniprot.org/uniprotkb/Q9VZK5" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZK5", "url": "https://www.uniprot.org/uniprotkb/Q9VZK5" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZK5", "url": "https://www.uniprot.org/uniprotkb/Q9VZK5" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VZK5", "url": "https://www.uniprot.org/uniprotkb/Q9VZK5" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VZK5", "url": "https://www.uniprot.org/uniprotkb/Q9VZK5" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VZK5", "url": "https://www.uniprot.org/uniprotkb/Q9VZK5" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZK5", "url": "https://www.uniprot.org/uniprotkb/Q9VZK5" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZK5", "url": "https://www.uniprot.org/uniprotkb/Q9VZK5" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VZK5", "url": "https://www.uniprot.org/uniprotkb/Q9VZK5" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VZK5", "url": "https://www.uniprot.org/uniprotkb/Q9VZK5" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], 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"categories": [ "Protein Classification", "Other" ] }, { "id": "NP_647817", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647817", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VZP2", "url": "https://www.uniprot.org/uniprotkb/Q9VZP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VZP2-1", "url": "https://www.uniprot.org/uniprotkb/Q9VZP2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVAAKYERLNTSGEAAGNGNGNASDAEDEEIELHLAQKTQLGNGHRLRQSNFKYASGKCGSGEAPCTNETATLAQENMMMQMAVGTLAIIFLYLALSISLTFYQTDINRQMPFPLAIVTYHLVVKFLLAAAARRIYRMRVGRSRVQLDWRLALRKMAPTGVASAIDIGFSNWGLALVPISLYTMTKSSTIVFILLFAIAFGLEKKSWYLVSIVGLIGTGLLMFTYKSTDFNALGFFFILFASLSSGLRWSFAQFIMQKSKLGLHNPIDMIYYMQPWMIASLVPLVIGIEGAGLIAVIEDLHNHTSNEITWAIARISAGALLAFLMEFSEFLVLCKTSSLTLSIAGIFKDICQLALAVTIRKDHLSVINYIGLIICLAGIVCHLLHKYSNMKEMQRQQELQLDNDQEESSPGEYKFNDGSAIVGVHVKSHSTLTVPLLEQTDSEDESGASNKQNASDVIFDVLKRRDMQR", "length": 469, "header": "tr|Q9VZP2-1|Q9VZP2_DROME Isoform 1 of Sugar phosphate transporter domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG14971 PE=4 SV=1 CANONICAL=Q9VZP2-1" }, "isoforms": [ { "isoform_ac": "Q9VZP2-1", "url": "https://www.uniprot.org/uniprotkb/Q9VZP2/entry#Q9VZP2-1", "sequence": { "sequence": "MVAAKYERLNTSGEAAGNGNGNASDAEDEEIELHLAQKTQLGNGHRLRQSNFKYASGKCGSGEAPCTNETATLAQENMMMQMAVGTLAIIFLYLALSISLTFYQTDINRQMPFPLAIVTYHLVVKFLLAAAARRIYRMRVGRSRVQLDWRLALRKMAPTGVASAIDIGFSNWGLALVPISLYTMTKSSTIVFILLFAIAFGLEKKSWYLVSIVGLIGTGLLMFTYKSTDFNALGFFFILFASLSSGLRWSFAQFIMQKSKLGLHNPIDMIYYMQPWMIASLVPLVIGIEGAGLIAVIEDLHNHTSNEITWAIARISAGALLAFLMEFSEFLVLCKTSSLTLSIAGIFKDICQLALAVTIRKDHLSVINYIGLIICLAGIVCHLLHKYSNMKEMQRQQELQLDNDQEESSPGEYKFNDGSAIVGVHVKSHSTLTVPLLEQTDSEDESGASNKQNASDVIFDVLKRRDMQR", "length": 469, "header": "tr|Q9VZP2-1|Q9VZP2_DROME Isoform 1 of Sugar phosphate transporter domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG14971 PE=4 SV=1 CANONICAL=Q9VZP2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VZP2", "url": "https://www.uniprot.org/uniprotkb/Q9VZP2" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VZP2", "url": "https://www.uniprot.org/uniprotkb/Q9VZP2" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZP2", "url": "https://www.uniprot.org/uniprotkb/Q9VZP2" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZP2", "url": "https://www.uniprot.org/uniprotkb/Q9VZP2" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VZP2", "url": "https://www.uniprot.org/uniprotkb/Q9VZP2" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VZP2", "url": "https://www.uniprot.org/uniprotkb/Q9VZP2" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VZP2", "url": "https://www.uniprot.org/uniprotkb/Q9VZP2" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZP2", "url": "https://www.uniprot.org/uniprotkb/Q9VZP2" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZP2", "url": "https://www.uniprot.org/uniprotkb/Q9VZP2" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VZP2", "url": "https://www.uniprot.org/uniprotkb/Q9VZP2" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VZP2", "url": "https://www.uniprot.org/uniprotkb/Q9VZP2" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG14971", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG14971", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BSR3-1", "protein_name": "Solute carrier family 35 member C2", "gene_name": "SLC35C2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGRWALDVAFLWRAVLTLGLVLLYYCFSIGITFYNKWLTKSFHFPLFMTMLHLAVIFLFSALSRALVQCSSHRARVVLSWTDYLRRVAPTALATALDVGLSNWSFLYITVSLYTMTKSSAVLFILIFSLIFKLEELRAALVLVVLLIAGGLFMFTYKSTQFNVEGFALVLGASFIGGIRWTLTQMLLQKAELGLQNPIDTMFHLQPLMFLGLFPLFAVFEGLHLSTSEKIFRFQDTGLLLRVLGSLFLGGILAFGLGFSEFLLVSRTSSLTLSIAGIFKEVCTLLLAAHLLGDQISLLNWLGFALCLSGISLHVALKALHARGDGAPKSLKGLGSNPDLELLLRTSQPDEEDNEEEYFVAQGQQ", "length": 364 }, "evidence": [ { "id": "Q9VZP2", "url": "https://omabrowser.org/oma/group/Q9VZP2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A3Q1M589-1", "protein_name": "Solute carrier family 35 member C2", "gene_name": "SLC35C2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGRCAPDVAFVWRAVLTLGLVLLYYCFSIGITFYNKWLTKSFHFPLFMTMLHLAVIFLFSALSRALAQCSSHRARVVLSWPDYLRRVAPTALATALDVGLSNWSFLYITVSLYTMTKSSAVLFILIFSLIFKLEELRAALVLVVLLIAGGLFMFTYKSTQFNIEGFALVLGASFIGGIRWTLTQMLLQKAELGLQNPIDTMFHLQPLMFLGLFPLFAVFEGLHLSTSEKIFRFQDTGLLLRVLGSLFLGGILAFGLGFSEFLLVSRTSSLTLSIAGIFKEVCTLLLAAHLLGDQISLLNWLGFALCLSGISLHIALKALHARGDGAPKPLKGLGSNPDLELLLRSSQPEDEDNEEEEYFVAQGQQ", "length": 365 }, "evidence": [ { "id": "Q9VZP2", "url": "https://omabrowser.org/oma/group/Q9VZP2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0AC58IIX0-1", "protein_name": "Collagen alpha-1(XX) chain", "gene_name": "slc35h1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MACPTHFLCKALRTVGLVLFYYAFSIGITFYNKWLMKDFHFPLFMTLVHLTIIFCLSTLTRSAMQCWTGKPRVTLPWKVYLSKVAPTALATTLDIGLSNWSFLFITISLYTMTKSSAVLFILFFSLLFKLEEPNPFLILVVVLISSGLFMFTLKSTQFNLEGFIMVLLASFIGGIRWTLTQLLMQKAELGLQNPIDTMYHLQPLMFLGLFPLFLLNEGLSVSTTEKLFRVSELSHLLYSLVTLSVGGMLAFGLGFSEFLLVSRTSSLTLSIAGIFKEVCTLLLAVEFLGDKMSTVNWLGFAVCLSGISLHIGLKTYRNKGFLIGTNTFTMAHISPLVLPERMTIFLVTVLLILVSEVQTQGRLKLTVLSEDRLQMKWKEAEGPVQGYKVRVRPITEVPQPELMLTTTRGRATVAGLDSRQEYLLQVMAINGTQEKLIAKRRFTIDGLREEELIRSGNREQKKKTPAIGSGSGEVDDVTEALEGLPTVLYREPTTTEPSVVPELEPEADQGTKEKKKKKDKNRSKAEDRIDQEENEGKSAKEEDSDTSKLRKTTPTQPGTAVSTRKPFECSAEAQAELVLLVDGSWSIGRTNFRKVREFLQGLAVPFHIGPEGVQIALSQYSGDPRTEWHLNNFTSKEPLLEAVRNFRYKGGNTFTGQALIHALENNLKEEVGARPNTPQFLLLLTDGKSQDDAIAAANRLKNAGVEIIAIGVKNADEAELRQVASEPLELNVYKVNDFPLLSKLVGKLARILCGKIEDRIKAKRMEHPTQEPVLSFPSPTDLQYVGLGSRELRLRWTVPSRNPQQYRVVYHTAEGQSLNELVVNGTESTTLLTGLSSQTQYHLSIFPVYENKVGSALRGTFTTLPLAIPEALEVTASSASSLRVRWQPAAGATQYMALYSALNDGEPDDAKEVKFGPAQTDVELVDLIPSTDYSVTLYALYDEDPSDPITAIGTTFPLPSPLSLQFPMVSHSTLMVTWVPGAVDVPAHRIIYSTNHGSDVKQVEVRGVNTVLLQNLSSLSRYLVSVHSLYEKGLSSPVTANVTTLRVPAPSDLRVTNFTGSEITVRWEAAADDVVFYLIKWISLNGGDLSQLMINGKGEGAILEKVEEDKEYQISLSASYADGAQSEAVAIRYSTLSGGGPSSLSISEETAVSMLVTWVHPNAHVQQYRVSFTPLNGDARENTVSLAGSERRILLQNLLPDTRYSVLVTAEYRSREGGSASAQGKTTSLRVSSVSVVRSDHSSICVSWRPVPAVSGYRIVIQALREKQTKEEMVDASSSSHCFSELQPETVYRISVHSRLGAVEGAAVTILHPTATAPVRVQVPPGLHPIQREVCPEMTVRNYVLKGFDMMEAFGLTQRAHSTIEGVAAEPFIFSTLPSYTLYRDVQLTQSTGFIHPAGFSPEHTISMVFRLLQDSPREPFALWQLTDNDFQPKMGVVLDPEKKVLLYFSLDYKGEIQELTFDQPQVHSIFYGSFHKIHLSVSQVSVSLSVDCQRVGERPARPLGTLPTDGFEMLGKLVKTRGPHSGSAAFQLQSFEIVCNTTWASEDSCCDLPSQRDEESCPAPAYACTCTTDVPGSPGDTGPSGKPGVRGEKGEKGEVGQKGEVGPPGKSGPEGGFGALGPAGPRGIAVMGKMGPPGARGEKGDIGRPGSQGLPGPPGQKGGEGNPGPKGTRGVEGNIGPPGITGPRGLQGMPGHPGPVGDRGPLGPVGPTGLPGSKGERGEKGEPQSLAMIYQLVSQACEKLVHNEVLKMDAFLNELNRKPVPIQEPVAPPGEPGIPGGRGAPGPRGPQGRLGSRGMPGKPGYPGEQGRRGMAGEKGSPGANAVGPQGMKGFGGPPGEAKIGEPGPKGEDGKAGPTGIPGAAGQQGEMGPSGVCDSSGCYQGPPAEDPYLGYRP", "length": 1897 }, "evidence": [ { "id": "RGD:1311250", "url": "https://alliancegenome.org/gene/RGD:1311250#orthology", "database": "AGR" }, { "id": "MGI:2385166", "url": "https://alliancegenome.org/gene/MGI:2385166#orthology", "database": "AGR" }, { "id": "HGNC:17117", "url": "https://alliancegenome.org/gene/HGNC:17117#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-2202", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-2202#orthology", "database": "AGR" }, { "id": "FB:FBgn0035449", "url": "https://alliancegenome.org/gene/FB:FBgn0035449#orthology", "database": "AGR" }, { "id": "SGD:S000004502", "url": "https://alliancegenome.org/gene/SGD:S000004502#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "B2RYM9-1", "protein_name": "Solute carrier family 35 member C2", "gene_name": "Slc35c2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRWALDVAFVWKAALTLGLVLLYYCFSIGITFYNKWLTKSFHFPLFMTMLHLAVIFLFSALSRALVQCSSHRARVVLSWTDYLRRVAPTALATALDVGLSNWSFLYITVSLYTMTKSSAVLFILIFSLIFKLEELRAALVLVVLLIAGGLFMFTYKSTQFNVEGFALVLGASFIGGIRWTLTQMLLQKADLGLQNPIDTMFHLQPLMFLGLFPLFAVFEGLHLSTSEKIFRFQDPGLLLWVLGSLLLGGILAFGLGFSEFLLVSRTSSLTLSIAGIFKEVCTLLLAAHLLGDQISLLNWLGFALCLSGISLHVALKALHSRGDGGPKPRKGLGSSADLELLLQSSQQEEDNGEEEYFMTQGQQ", "length": 364 }, "evidence": [ { "id": "RGD:1311250", "url": "https://alliancegenome.org/gene/RGD:1311250#orthology", "database": "AGR" }, { "id": "MGI:2385166", "url": "https://alliancegenome.org/gene/MGI:2385166#orthology", "database": "AGR" }, { "id": "HGNC:17117", "url": "https://alliancegenome.org/gene/HGNC:17117#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-2202", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-2202#orthology", "database": "AGR" }, { "id": "FB:FBgn0035449", "url": "https://alliancegenome.org/gene/FB:FBgn0035449#orthology", "database": "AGR" }, { "id": "SGD:S000004502", "url": "https://alliancegenome.org/gene/SGD:S000004502#orthology", "database": "AGR" }, { "id": "Q9VZP2", "url": "https://omabrowser.org/oma/group/Q9VZP2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q03697-1", "protein_name": "Putative nucleotide-sugar transporter YMD8", "gene_name": "YMD8", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MNRTVFLAFVFGWYFCSIALSIYNRWMFDPKDGLGIGYPVLVTTFHQATLWLLSGIYIKLRHKPVKNVLRKNNGFNWSFFLKFLLPTAVASAGDIGLSNVSFQYVPLTIYTIIKSSSIAFVLLFGCIFKLEKFHWKLALSVIIMFVGVALMVFKPSDSTSTKNDQALVIFGSFLVLASSCLSGLRWVYTQLMLRNNPIQTNTAAAVEESDGALFTENEDNVDNEPVVNLANNKMLENFGESKPHPIHTIHQLAPIMGITLLLTSLLVEKPFPGIFSSSIFRLDTSNGGVGTETTVLSIVRGIVLLILPGFAVFLLTICEFSILEQTPVLTVSIVGIVKELLTVIFGIIILSERLSGFYNWLGMLIIMADVCYYNYFRYKQDLLQKYHSVSTQDNRNELKGFQDFEQLGSKKIAPYSISVDLTNQEYELDMIAQNVSRSSQQV", "length": 442 }, "evidence": [ { "id": "RGD:1311250", "url": "https://alliancegenome.org/gene/RGD:1311250#orthology", "database": "AGR" }, { "id": "MGI:2385166", "url": "https://alliancegenome.org/gene/MGI:2385166#orthology", "database": "AGR" }, { "id": "HGNC:17117", "url": "https://alliancegenome.org/gene/HGNC:17117#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-2202", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-2202#orthology", "database": "AGR" }, { "id": "FB:FBgn0035449", "url": "https://alliancegenome.org/gene/FB:FBgn0035449#orthology", "database": "AGR" }, { "id": "SGD:S000004502", "url": "https://alliancegenome.org/gene/SGD:S000004502#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q8VCX2-1", "protein_name": "Solute carrier family 35 member H1", "gene_name": "Slc35h1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGRWALDVAFVWKAALTLGLVLLYYCFSIGITFYNKWLTKSFHFPLFMTMLHLAVIFLFSALSRALVQCSSHKARVVLSWTDYLRRVAPTALATALDVGLSNWSFLYITVSLYTMTKSSAVLFILIFSLIFKLEELRAALVLVVLLIAGGLFMFTYKSTQFNVEGFALVLGASFIGGIRWTLTQILLQKADLGLQNPIDTMFHLQPLMFLGLFPLFAIFEGLHLSTSEKIFRFQDTGLLLWVLGSLLLGGILAFGLGFSEFLLVSRTSSLTLSIAGIFKEVCTLLLAAHLLGDQISLLNWLGFALCLSGISLHVALKALHSRGDGGPKPLKSLGSSADLELLLRSSQQEEEDGEEEYFVTQGQQ", "length": 364 }, "evidence": [ { "id": "RGD:1311250", "url": "https://alliancegenome.org/gene/RGD:1311250#orthology", "database": "AGR" }, { "id": "MGI:2385166", "url": "https://alliancegenome.org/gene/MGI:2385166#orthology", "database": "AGR" }, { "id": "HGNC:17117", "url": "https://alliancegenome.org/gene/HGNC:17117#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-2202", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-2202#orthology", "database": "AGR" }, { "id": "FB:FBgn0035449", "url": "https://alliancegenome.org/gene/FB:FBgn0035449#orthology", "database": "AGR" }, { "id": "SGD:S000004502", 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"Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VZQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VZQ5" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VZQ5" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VZQ5" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VZQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VZQ5" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VZQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VZQ5" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VZQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VZQ5" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VZQ5" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZQ5", "url": "https://www.uniprot.org/uniprotkb/Q9VZQ5" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VZU0", "url": "https://www.uniprot.org/uniprotkb/Q9VZU0" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VZU0", "url": "https://www.uniprot.org/uniprotkb/Q9VZU0" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi 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"database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VZU1", "url": "https://www.uniprot.org/uniprotkb/Q9VZU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VZU1-1", "url": "https://www.uniprot.org/uniprotkb/Q9VZU1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHSEKHTPDIRELMPVREHRCERCPSLVFGNLSHYQLHLRRRHQEVIPPSVIGPIVAFHCPVEKCIYHVATKGARSFTSLRLLRQHYQKSHLDKNYKCLACGGKFLLQHHLEKHQCSKHKCPVCELTYNSKAGLRTHMRRKNHLVHHESDKVPIPSLATWKRLNPQPIPVSADSLTAHSLKTGSDLHPSEEYINNLPSNLAGVTELYAEIPNPEANMPSTLELDTNLPAAEEHILCFLPIMDVSYALEMSSQKLDMETQTEEDDLNEIRNEVLAPLLRDIETQTPDTRGDIGTMTDDFPEEQEPVAVGSHFHAYSETEPMFDLQTSAHMYTQTCDDLFEELGLSHIQTQTHWPDGLYNTQHTQTCDEIMDELFPDNFQSTCTQTRWLD", "length": 388, "header": "tr|Q9VZU1-1|Q9VZU1_DROME Isoform 1 of ASCIZ zinc finger protein, isoform A OS=Drosophila melanogaster OX=7227 GN=Asciz PE=4 SV=1 CANONICAL=Q9VZU1-1" }, "isoforms": [ { "isoform_ac": "Q9VZU1-1", "url": "https://www.uniprot.org/uniprotkb/Q9VZU1/entry#Q9VZU1-1", "sequence": { "sequence": "MHSEKHTPDIRELMPVREHRCERCPSLVFGNLSHYQLHLRRRHQEVIPPSVIGPIVAFHCPVEKCIYHVATKGARSFTSLRLLRQHYQKSHLDKNYKCLACGGKFLLQHHLEKHQCSKHKCPVCELTYNSKAGLRTHMRRKNHLVHHESDKVPIPSLATWKRLNPQPIPVSADSLTAHSLKTGSDLHPSEEYINNLPSNLAGVTELYAEIPNPEANMPSTLELDTNLPAAEEHILCFLPIMDVSYALEMSSQKLDMETQTEEDDLNEIRNEVLAPLLRDIETQTPDTRGDIGTMTDDFPEEQEPVAVGSHFHAYSETEPMFDLQTSAHMYTQTCDDLFEELGLSHIQTQTHWPDGLYNTQHTQTCDEIMDELFPDNFQSTCTQTRWLD", "length": 388, "header": "tr|Q9VZU1-1|Q9VZU1_DROME Isoform 1 of ASCIZ zinc finger protein, isoform A OS=Drosophila melanogaster OX=7227 GN=Asciz PE=4 SV=1 CANONICAL=Q9VZU1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VZU1", "url": "https://www.uniprot.org/uniprotkb/Q9VZU1" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VZU1", "url": "https://www.uniprot.org/uniprotkb/Q9VZU1" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZU1", "url": "https://www.uniprot.org/uniprotkb/Q9VZU1" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZU1", "url": "https://www.uniprot.org/uniprotkb/Q9VZU1" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VZU1", "url": "https://www.uniprot.org/uniprotkb/Q9VZU1" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VZU1", "url": "https://www.uniprot.org/uniprotkb/Q9VZU1" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VZU1", "url": "https://www.uniprot.org/uniprotkb/Q9VZU1" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZU1", "url": "https://www.uniprot.org/uniprotkb/Q9VZU1" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZU1", "url": "https://www.uniprot.org/uniprotkb/Q9VZU1" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VZU1", "url": "https://www.uniprot.org/uniprotkb/Q9VZU1" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VZU1", "url": "https://www.uniprot.org/uniprotkb/Q9VZU1" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG14962", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG14962", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M6YW05-1", "protein_name": "ATM interactor isoform X1", "gene_name": "atmin", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAAATVNNNSRHKRQKCSEKLPLQDREIIKPSITELTKEVRTNILCTVEGCGKILPNTPALNMHLVKSHRVQEGLVNPTIRKGDKNSQKLYCCPIEGCPRGPNRPFSQFSLVKQHFMKMHAEKKHKCLKCSNGYSTEWDLRRHVEDCGRTYSCTCGCPYASRAALLSHIYRTGHEVPKEHRYPPVKKRKMERLSSGATSFLLDEQIDDMPDSKKKLTEGTATTILVSEAPDAAQYNTNQPRHIQKLLLPKPKVALVNVPVMQFAHLPVLLPSTESSALRSLVLSLDAQGSVSTVHILSPSIGTMVPDLNNKTFKETFPVSTLGPETISTGVQVNLESQASVEDPLIDHGIKSKSTSTNIQTDITYLNKEMGTGPETVSLNEASVSSCSQTDISVSAQIQLPISVQTQTLPSRIKATFSIGAQTDFFSFSSFNVTRETQTSCSVAPLNESQMDQAMCTNLFDPDTLSVSTQTATVDAPFRTSGLEGPLTCTGAELFEDKSSASMCFGAQTDQNTVADNQTQTMILFRDLENILSDSMSGATSSCASGLVAGHESQNTGIDFDFEEFLNATHIQTQTEESGLNTLNTETTLELLDIETQTDFLLFDNLGNGHNSDVGTRVQPNDLELEMFDTQTQTDLNFLLETSGHMPLGSILRQSSFSMSTESSDTETQTDIRPAPLSLPCSHDGQVRLSSAETQTISSSFHSLGHLFHTSNETQTAVDDFLSADLAWNMESHFSSVETQTCEELLSLFRHTEKVKD", "length": 757 }, "evidence": [ { "id": "RGD:1305781", "url": "https://alliancegenome.org/gene/RGD:1305781#orthology", "database": "AGR" }, { "id": "HGNC:29034", "url": "https://alliancegenome.org/gene/HGNC:29034#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030616-220", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030616-220#orthology", "database": "AGR" }, { "id": "MGI:2682328", "url": "https://alliancegenome.org/gene/MGI:2682328#orthology", "database": "AGR" }, { "id": "FB:FBgn0035407", "url": "https://alliancegenome.org/gene/FB:FBgn0035407#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1LN81-1", "protein_name": "ATM interactor", "gene_name": "Atmin", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAATEAAAAESAGPAPGVPVTPASTRGAAAASSPWRPSESRLQGSRPRLARARAAAPVPPARELIQPSVSELSRAVRTNILCTVRGCGKILPNSPALNMHLVKSHRLQDGIVNPTIRKDLKTVPKFYCCPIKGCPRGPDRPFSQFSLVKQHFMKMHAEKKHKCSKCSNSYGTEWDLRRHEEDCGKTFQCTCGCPYASRTALQSHIYRTGHEIPAEHRDPPSKKRKIESQTLSTKTIGPLGDQPAPRQDAHEPRASEVKLAASLEDSCSSHTKKQSFPTPPRCPQKLLLPKPKVALVKLPVMQFSPVPVFVPTADSSAQPVVLGVDHSSAAGAVHLVPLSVGTLILSLDSEACSLKESLPLSKIISPVVEPMNTGVQVNLGKSLCRPLQEGGSVCQKNSISSANVQTDLSYASANLIPSAQWLGPDSSVSSCSQTDLSFDSQVSLPVSVHTQTLVPSSKVTSSIAAQTDAFLDACFQPSGVSRETQTCRIQNRTDDPVPVGHPGLCGDIFEGVHSSYGVPSDNIMSSSLVAETVTHSLVPQSDPKILSQVMEKSAPVLNFSAQNSMLPSQNMTDNQTQTIDLLSDLENILSSNLPGQTLDNRSLLSDTNPGPDAQLPSGSAQNSGIDFDIEEFLSASNIQTQTEESELSSMSTEPVLESLDIETQTDLFLSDPCTQPYGLRAGSGFLGLEMFDTQTQTDLNFFLDSSPHLPLGSILRHSSFSMSTDSSDTETQTEGASPARHAPTLESKVQLSSTETQTMSSGFEPLGNLFLTSNETQTAMDDFLLADLAWNTMESQFSSVETQTCAELHAVSSF", "length": 814 }, "evidence": [ { "id": "RGD:1305781", "url": "https://alliancegenome.org/gene/RGD:1305781#orthology", "database": "AGR" }, { "id": "HGNC:29034", "url": "https://alliancegenome.org/gene/HGNC:29034#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030616-220", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030616-220#orthology", "database": "AGR" }, { "id": "MGI:2682328", "url": "https://alliancegenome.org/gene/MGI:2682328#orthology", "database": "AGR" }, { "id": "FB:FBgn0035407", "url": "https://alliancegenome.org/gene/FB:FBgn0035407#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O43313-1", "protein_name": "ATM interactor", "gene_name": "ATMIN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAASEAAAAAGSAALAAGARAVPAATTGAAAAASGPWVPPGPRLRGSRPRPAGATQQPAVPAPPAGELIQPSVSELSRAVRTNILCTVRGCGKILPNSPALNMHLVKSHRLQDGIVNPTIRKDLKTGPKFYCCPIEGCPRGPERPFSQFSLVKQHFMKMHAEKKHKCSKCSNSYGTEWDLKRHAEDCGKTFRCTCGCPYASRTALQSHIYRTGHEIPAEHRDPPSKKRKMENCAQNQKLSNKTIESLNNQPIPRPDTQELEASEIKLEPSFEDSCGSNTDKQTLTTPPRYPQKLLLPKPKVALVKLPVMQFSVMPVFVPTADSSAQPVVLGVDQGSATGAVHLMPLSVGTLILGLDSEACSLKESLPLFKIANPIAGEPISTGVQVNFGKSPSNPLQELGNTCQKNSISSINVQTDLSYASQNFIPSAQWATADSSVSSCSQTDLSFDSQVSLPISVHTQTFLPSSKVTSSIAAQTDAFMDTCFQSGGVSRETQTSGIESPTDDHVQMDQAGMCGDIFESVHSSYNVATGNIISNSLVAETVTHSLLPQNEPKTLNQDIEKSAPIINFSAQNSMLPSQNMTDNQTQTIDLLSDLENILSSNLPAQTLDHRSLLSDTNPGPDTQLPSGPAQNPGIDFDIEEFFSASNIQTQTEESELSTMTTEPVLESLDIETQTDFLLADTSAQSYGCRGNSNFLGLEMFDTQTQTDLNFFLDSSPHLPLGSILKHSSFSVSTDSSDTETQTEGVSTAKNIPALESKVQLNSTETQTMSSGFETLGSLFFTSNETQTAMDDFLLADLAWNTMESQFSSVETQTSAEPHTVSNF", "length": 823 }, "evidence": [ { "id": "RGD:1305781", "url": "https://alliancegenome.org/gene/RGD:1305781#orthology", "database": "AGR" }, { "id": "HGNC:29034", "url": "https://alliancegenome.org/gene/HGNC:29034#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030616-220", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030616-220#orthology", "database": "AGR" }, { "id": "MGI:2682328", "url": "https://alliancegenome.org/gene/MGI:2682328#orthology", "database": "AGR" }, { "id": "FB:FBgn0035407", "url": "https://alliancegenome.org/gene/FB:FBgn0035407#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6P9S1-1", "protein_name": "ATM interactor", "gene_name": "Atmin", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAATEAAAADSAGPAPGVPATPASTRGAAAASSPWRPPESRLQGSRPRPARARAAAPVPPARELIQPTVSELSRAVRTNILCTVRGCGKILPNSPALNMHLVKSHRLQDGIVNPTIRKDLTTAPKFYCCPIKGCPRGPDRPFSQFSLVKQHFMKMHAEKKHKCSKCSNSYGTEWDLKRHEEDCGKTFQCTCGCPYASRTALQSHIYRTGHEIPAEHRDPPSKKRKMESYLQNQKLSSKTTEPLSDQAAPRQDAAEPDAPEVKPAASLEDSCSAHTKKQSVATPPRCPQKLLLPKPKVALVKLPVMQFSPVPVFVPTAESSAQPVVLGVDHSSAAGTVHLVPLSVGALILSLDSEACSLKESLPLSKIISPVVEPMNTGVQVNLGKSLCSPLQEVGSVCQRTSISSSNVQTDLTYASANLIPSAQWLGPDSSVSSCSQTDLSFDSQVSLPVSVHTQTLVPSSKVTSSIAAQTDAFIDACFQPGGVSRETQTSRMQNRTNDSVPVGHTGLCGDIFESVHASYSVPTDTIMSSSLVAETGTHGLPPQSDPKILGQVMEKSAPVLNFSTQNGLLPAHTMTDNQTQTIDLLSDLENILSSNLPGQTLDNRSLLSDTNPGPDAQLPAGSAQNSGIDFDIEEFLSASNIQTQTEESELSSMSTEPVLESLDIETQTDVLLSDPSTQPYGFRAGSGFLGLEMFDTQTQTDLNFFLDSSPHLPLGSILKHSSFSMSTDSSDTETQTEGACPARHLPALESKVQLSSTETQTMSSGFEPLGNLFLTSNETQTAMDDFLLADLAWNTMESQFSSVETQTCAELHAVSSF", "length": 818 }, "evidence": [ { "id": "RGD:1305781", "url": "https://alliancegenome.org/gene/RGD:1305781#orthology", "database": "AGR" }, { "id": "HGNC:29034", "url": "https://alliancegenome.org/gene/HGNC:29034#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030616-220", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030616-220#orthology", "database": "AGR" }, { "id": "MGI:2682328", "url": "https://alliancegenome.org/gene/MGI:2682328#orthology", "database": "AGR" }, { "id": "FB:FBgn0035407", "url": "https://alliancegenome.org/gene/FB:FBgn0035407#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9VZU1", "url": "https://www.uniprot.org/uniprotkb/Q9VZU1" } ], "pmid": "" }, { "name": "spindle matrix", "id": "GO:1990047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990047", "evidence": [ { "database": "UniProtKB", "id": "Q9VZU1", "url": 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"https://monarchinitiative.org/disease/MONDO:0012265", "name": "PEE3", "description": "" }, { "id": "MONDO:0012265", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012265", "name": "PREECLAMPSIA/eclampsia 3", "description": "" }, { "id": "MONDO:0012266", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012266", "name": "preeclampsia/eclampsia 4", "description": "Any preeclampsia in which the cause of the disease is a mutation in the STOX1 gene." }, { "id": "MONDO:0012266", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012266", "name": "Preeclampsia/eclampsia type 4", "description": "" }, { "id": "MONDO:0012266", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012266", "name": "STOX1 preeclampsia", "description": "" }, { "id": "MONDO:0012266", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012266", "name": "preeclampsia caused by mutation in STOX1", "description": "" }, { "id": "MONDO:0012266", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012266", "name": "preeclampsia/eclampsia 4", "description": "" }, { "id": "MONDO:0012266", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012266", "name": "PEE4", "description": "" }, { "id": "MONDO:0100467", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0100467", "name": "preeclampsia/eclampsia 1", "description": "" }, { "id": "MONDO:0100467", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0100467", "name": "toxaemia of pregnancy", "description": "" }, { "id": "MONDO:0100467", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0100467", "name": "toxemia of pregnancy", "description": "" }, { "id": "MONDO:0100467", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0100467", "name": "PEE1", "description": "" }, { "id": "MONDO:0100467", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0100467", "name": "PREECLAMPSIA/eclampsia 1", "description": "" }, { "id": "MONDO:0100467", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0100467", "name": "PREG1", "description": "" }, { "id": "MIM:609404", "resource": "MIM", "url": "https://www.omim.org/entry/609404", "name": "Pre-eclampsia/eclampsia 4", "description": "Pre-eclampsia/eclampsia 4" } ], "unlinked_id_list": [], "evidence": [ { "id": "10591", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10591" } ] }, { "disease_id": "DOID:10763", "recommended_name": { "id": "DOID:10763", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries." }, "synonyms": [ { "id": "DOID:10763", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10763", "name": "HTN", "description": "" }, { "id": "DOID:10763", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10763", "name": "hyperpiesia", "description": "" }, { "id": "DOID:10763", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10763", "name": "vascular hypertensive disorder", "description": "" } ], "unlinked_id_list": [ "DOID:13731", "DOID:11130" ], "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ] }, { "disease_id": "DOID:11335", "recommended_name": { "id": "DOID:11335", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11335", "name": "sarcoidosis", "description": "A hypersensitivity reaction type IV disease characterized by the growth of collections of inflammatory cells (granulomas) in multiple organs." }, "synonyms": [ { "id": "DOID:11335", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11335", "name": "Boeck sarcoid", "description": "" }, { "id": "DOID:11335", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11335", "name": "lymphogranulomatosis", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "11335", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11335" } ] }, { "disease_id": "DOID:11650", "recommended_name": { "id": "DOID:11650", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11650", "name": "bronchopulmonary dysplasia", "description": "A lung disease that is characterized by underdeveloped lungs in newborns that can be easily irritated or inflamed after birth resulting in damage to the alveoli of the lungs and bronchi. Most newborns who develop BPD are born more than 10 weeks before their due dates, weigh less than 2 pounds at birth, and have breathing problems." }, "synonyms": [ { "id": "DOID:11650", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11650", "name": "Perinatal bronchopulmonary dysplasia", "description": "" }, { "id": "DOID:11650", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11650", "name": "neonatal chronic respiratory disease", "description": "" }, { "id": "DOID:11650", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11650", "name": "Bronchopulmonary dysplasia of newborn", "description": "" }, { "id": "DOID:11650", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11650", "name": "Chronic lung disease of prematurity", "description": "" }, { "id": "DOID:11650", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11650", "name": "Neonatal chronic lung disease", "description": "" }, { "id": "DOID:11650", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11650", "name": "Respiratory insufficiency", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "11650", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11650" } ] }, { "disease_id": "DOID:1205", "recommended_name": { "id": "DOID:1205", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1205", "name": "allergic disease", "description": "An immune system disease that is an exaggerated immune response to allergens, such as insect venom, dust mites, pollen, pet dander, drugs or some foods." }, "synonyms": [ { "id": "DOID:1205", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1205", "name": "hypersensitivity", "description": "" }, { "id": "DOID:1205", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1205", "name": "hypersensitivity reaction type I disease", "description": "" }, { "id": "DOID:1205", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1205", "name": "allergic hypersensitivity disease", "description": "" } ], "unlinked_id_list": [ "DOID:0080811", "DOID:0060502", "DOID:0060503", "DOID:0060904" ], "evidence": [ { "id": "1205", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1205" } ] }, { "disease_id": "DOID:13375", "recommended_name": { "id": "DOID:13375", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13375", "name": "temporal arteritis", "description": "A central nervous system vasculitis that is characterized by inflammation of the lining of arteries, often arteries in the head." }, "synonyms": [ { "id": "DOID:13375", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13375", "name": "Horton's disease", "description": "" }, { "id": "DOID:13375", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13375", "name": "giant cell arteritis", "description": "" }, { "id": "MONDO:0008538", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008538", "name": "temporal arteritis", "description": "A large vessel vasculitis predominantly involving the arteries originating from the aortic arch and especially the extracranial branches of the carotid arteries." }, { "id": "MONDO:0008538", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008538", "name": "Giant Cell Arteritis", "description": "" }, { "id": "MONDO:0008538", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008538", "name": "Horton disease", "description": "" }, { "id": "MONDO:0008538", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008538", "name": "giant cell arteritis", "description": "" }, { "id": "MONDO:0008538", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008538", "name": "inflammation of temporal artery", "description": "" }, { "id": "MONDO:0008538", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008538", "name": "temporal arteritis", "description": "" }, { "id": "MONDO:0008538", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008538", "name": "temporal artery inflammation", "description": "" }, { "id": "MONDO:0008538", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008538", "name": "GCA", "description": "" }, { "id": "MONDO:0008538", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008538", "name": "Horton's arteritis", "description": "" }, { "id": "MONDO:0008538", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008538", "name": "Horton's giant cell arteritis", "description": "" }, { "id": "MONDO:0008538", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008538", "name": "Horton's temporal arteritis", "description": "" }, { "id": "MONDO:0008538", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008538", "name": "Hortons disease", "description": "" }, { "id": "MONDO:0008538", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008538", "name": "Hortons syndrome", "description": "" }, { "id": "MONDO:0008538", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008538", "name": "arteritis cranialis", "description": "" }, { "id": "MONDO:0008538", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008538", "name": "arteritis temporalis", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "13375", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13375" } ] }, { "disease_id": "DOID:13406", "recommended_name": { "id": "DOID:13406", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13406", "name": "pulmonary sarcoidosis", "description": "A sarcoidosis that is characterized by noncaseating granulomatous infiltration of the lungs and supporting lymph nodes, bilateral hilar adenopathy, and pulmonary issues, has_symptom shortness of breath, fatigue, wheezing, and chronic cough, and develops_from a type IV hypersensitivity reaction." }, "synonyms": [ { "id": "DOID:13406", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13406", "name": "lung Sarcoidosis", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "13406", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13406" } ] }, { "disease_id": "DOID:13564", "recommended_name": { "id": "DOID:13564", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13564", "name": "aspergillosis", "description": "An opportunistic mycosis that involves a spectrum of diseases of humans and animals caused by members of the genus Aspergillus infecting lungs, brain, kidney, heart, bone, eyes, sinuses, skin and gastrointestinal tract. It is a serious illnesses in people with a weakened immune system." }, "synonyms": [ { "id": "DOID:13564", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13564", "name": "Infection due to Aspergillus", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "13564", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13564" } ] }, { "disease_id": "DOID:1380", "recommended_name": { "id": "DOID:1380", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1380", "name": "endometrial cancer", "description": "A uterine cancer that is located_in tissues lining the uterus." }, "synonyms": [ { "id": "DOID:1380", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1380", "name": "endometrial Ca", "description": "" }, { "id": "DOID:1380", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1380", "name": "endometrial neoplasm", "description": "" }, { "id": "DOID:1380", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1380", "name": "malignant endometrial neoplasm", "description": "" }, { "id": "DOID:1380", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1380", "name": "malignant neoplasm of endometrium", "description": "" }, { "id": "DOID:1380", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1380", "name": "neoplasm of endometrium", "description": "" }, { "id": "DOID:1380", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1380", "name": "primary malignant neoplasm of endometrium", "description": "" }, { "id": "DOID:1380", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1380", "name": "tumor of Endometrium", "description": "" }, { "id": "MONDO:0011962", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011962", "name": "endometrial cancer", "description": "Primary or metastatic malignant neoplasm involving the endometrium (mucous membrane that lines the endometrial cavity)." }, { "id": "MONDO:0011962", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011962", "name": "endometrial neoplasm", "description": "" }, { "id": "MONDO:0011962", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011962", "name": "neoplasm of endometrium", "description": "" }, { "id": "MONDO:0011962", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011962", "name": "tumor of endometrium", "description": "" }, { "id": "MONDO:0011962", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011962", "name": "tumour of endometrium", "description": "" }, { "id": "MONDO:0011962", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011962", "name": "cancer of endometrium", "description": "" }, { "id": "MONDO:0011962", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011962", "name": "endometrial cancer", "description": "" }, { "id": "MONDO:0011962", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011962", "name": "endometrial cancer, familial, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0011962", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011962", "name": "endometrial cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0011962", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011962", "name": "endometrial carcinoma, somatic", "description": "" }, { "id": "MONDO:0011962", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011962", "name": "endometrium cancer", "description": "" }, { "id": "MONDO:0011962", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011962", "name": "malignant endometrial neoplasm", "description": "" }, { "id": "MONDO:0011962", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011962", "name": "malignant endometrium neoplasm", "description": "" }, { "id": "MONDO:0011962", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011962", "name": "malignant neoplasm of endometrium", "description": "" }, { "id": "MIM:608089", "resource": "MIM", "url": "https://www.omim.org/entry/608089", "name": "Endometrial cancer", "description": "Endometrial cancer" } ], "unlinked_id_list": [ "DOID:5166" ], "evidence": [ { "id": "1380", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1380" } ] }, { "disease_id": "DOID:1485", "recommended_name": { "id": "DOID:1485", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1485", "name": "cystic fibrosis", "description": "A syndrome that is characterized by the buildup of thick, sticky mucus that can damage many organs." }, "synonyms": [ { "id": "DOID:1485", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1485", "name": "CF", "description": "" }, { "id": "DOID:1485", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1485", "name": "mucoviscidosis", "description": "" }, { "id": "MONDO:0009061", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009061", "name": "cystic fibrosis", "description": "Autosomal recessive disorder caused by pathogenic variants in the CFTR gene (cystic fibrosis transmembrane conductance regulator), which encodes a chloride and bicarbonate channel expressed in epithelial cells, and follow the diagnosis criteria. Diagnosis requires evidence of CFTR dysfunction, defined as a sweat chloride concentration of 60 mmol/L or greater, or identification of two CF-causing CFTR pathogenic variants, or an abnormal nasal potential difference measurement. CF is a progressive, multi-organ disease characterized by chronic obstructive lung disease with recurrent infections, exocrine pancreatic insufficiency, intestinal obstruction (including meconium ileus in neonates), male infertility due to obstructive azoospermia, hepatobiliary complications, and elevated sweat chloride concentrations." }, { "id": "MONDO:0009061", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009061", "name": "CF", "description": "" }, { "id": "MONDO:0009061", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009061", "name": "cystic fibrosis", "description": "" }, { "id": "MONDO:0009061", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009061", "name": "cystic fibrosis lung disease, modifier of", "description": "" }, { "id": "MONDO:0009061", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009061", "name": "mucoviscidosis", "description": "" }, { "id": "MONDO:0009061", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009061", "name": "pseudomonas aeruginosa, susceptibility to chronic infection by, in cystic fibrosis", "description": "" }, { "id": "MONDO:0009061", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009061", "name": "fibrocystic disease of the pancreas", "description": "" }, { "id": "MIM:219700", "resource": "MIM", "url": "https://www.omim.org/entry/219700", "name": "Cystic fibrosis", "description": "Cystic fibrosis" } ], "unlinked_id_list": [], "evidence": [ { "id": "1485", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1485" } ] }, { "disease_id": "DOID:1508", "recommended_name": { "id": "DOID:1508", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1508", "name": "candidiasis", "description": "An opportunistic mycosis that involves fungal infection of the mouth, throat, skin, scalp, vagina, fingers, nails, bronchi, lungs, heart and brain by Candida species, of which Candida albicans is the most common. Systemic Candida infections are usually confined to severely immunocompromised persons." }, "synonyms": [ { "id": "DOID:1508", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1508", "name": "Disseminated candidiasis", "description": "" }, { "id": "DOID:1508", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1508", "name": "systemic candidiasis", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "1508", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1508" } ] }, { "disease_id": "DOID:1612", "recommended_name": { "id": "DOID:1612", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland." }, "synonyms": [ { "id": "DOID:1612", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1612", "name": "breast tumor", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1612", "name": "malignant neoplasm of breast", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1612", "name": "malignant tumor of the breast", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1612", "name": "mammary cancer", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1612", "name": "mammary tumor", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1612", "name": "primary breast cancer", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "hereditary breast carcinoma", "description": "Breast carcinoma that has developed in relatives of patients with history of breast carcinoma." }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer susceptibility, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, early-onset, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, invasive ductal, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, lobular, somatic", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, male, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, protection against, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, somatic", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial breast cancer", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial breast carcinoma", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial cancer of breast", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial cancer of the breast", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "hereditary breast cancer", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "hereditary breast carcinoma", "description": "" }, { "id": "MIM:114480", "resource": "MIM", "url": "https://www.omim.org/entry/114480", "name": "Breast cancer", "description": "Breast cancer" } ], "unlinked_id_list": [ "DOID:3017", "DOID:0050938" ], "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ] }, { "disease_id": "DOID:1909", "recommended_name": { "id": "DOID:1909", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1909", "name": "melanoma", "description": "A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from melanocytes which are found in skin, the bowel and the eye." }, "synonyms": [ { "id": "DOID:1909", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1909", "name": "Naevocarcinoma", "description": "" }, { "id": "DOID:1909", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1909", "name": "malignant melanoma", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "1909", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1909" } ] }, { "disease_id": "DOID:1926", "recommended_name": { "id": "DOID:1926", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1926", "name": "Gaucher's disease", "description": "A sphingolipidosis characterized by deficiency of the enzyme glucocerebrosidase which results in the accumulation of harmful quantities of the glycolipid glucocerebroside throughout the body, especially within the bone marrow, spleen and liver." }, "synonyms": [ { "id": "DOID:1926", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1926", "name": "Gaucher disease", "description": "" }, { "id": "DOID:1926", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1926", "name": "acid beta-glucosidase deficiency", "description": "" }, { "id": "DOID:1926", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1926", "name": "glocucerebrosidase deficiency", "description": "" }, { "id": "DOID:1926", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1926", "name": "glucosylceramide beta-glucosidase deficiency", "description": "" }, { "id": "DOID:1926", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1926", "name": "kerasin thesaurismosis", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "1926", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1926" } ] }, { "disease_id": "DOID:2349", "recommended_name": { "id": "DOID:2349", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2349", "name": "arteriosclerosis", "description": "An artery disease that is characterized by a thickening and hardening of arterial walls in the arteries." }, "synonyms": [ { "id": "DOID:2349", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2349", "name": "Arteriosclerotic vascular disease", "description": "" } ], "unlinked_id_list": [ "DOID:2348" ], "evidence": [ { "id": "2349", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2349" } ] }, { "disease_id": "DOID:2378", "recommended_name": { "id": "DOID:2378", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2378", "name": "relapsing-remitting multiple sclerosis", "description": "A multiple sclerosis that is characterized by relapse (attacks of symptom flare-ups) followed by remission (periods of recovery). Symptoms may vary from mild to severe, and relapses and remissions may last for days or months. More than 80 percent of people who have MS begin with relapsing-remitting cycles." }, "synonyms": [ { "id": "DOID:2378", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2378", "name": "RRMS", "description": "" }, { "id": "DOID:2378", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2378", "name": "Relapsing-remitting MS", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "2378", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2378" } ] }, { "disease_id": "DOID:2394", "recommended_name": { "id": "DOID:2394", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2394", "name": "ovarian cancer", "description": "A female reproductive organ cancer that is located_in the ovary." }, "synonyms": [ { "id": "DOID:2394", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2394", "name": "malignant Ovarian tumor", "description": "" }, { "id": "DOID:2394", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2394", "name": "malignant tumour of ovary", "description": "" }, { "id": "DOID:2394", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2394", "name": "ovarian neoplasm", "description": "" }, { "id": "DOID:2394", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2394", "name": "ovary neoplasm", "description": "" }, { "id": "DOID:2394", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2394", "name": "primary ovarian cancer", "description": "" }, { "id": "DOID:2394", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2394", "name": "tumor of the Ovary", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "ovarian cancer", "description": "A primary or metastatic malignant neoplasm involving the ovary. Most primary malignant ovarian neoplasms are either carcinomas (serous, mucinous, or endometrioid adenocarcinomas) or malignant germ cell tumors. Metastatic malignant neoplasms to the ovary include carcinomas, lymphomas, and melanomas." }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "ovarian neoplasm", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "ovary neoplasm", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "tumor of the ovary", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "tumour of the ovary", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "cancer of ovary", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "cancer of the ovary", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "malignant neoplasm of ovary", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "malignant neoplasm of the ovary", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "malignant ovarian neoplasm", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "malignant ovarian tumor", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "malignant ovarian tumour", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "malignant ovary neoplasm", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "malignant tumor of ovary", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "malignant tumor of the ovary", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "malignant tumour of ovary", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "malignant tumour of the ovary", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "ovarian cancer", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "ovarian cancer, somatic", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "ovarian malignant tumor", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "ovarian malignant tumour", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "ovary cancer", "description": "" }, { "id": "MONDO:0011931", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011931", "name": "ovarian cancer, susceptibility to, 1", "description": "" }, { "id": "MONDO:0011931", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011931", "name": "OVCAS1", "description": "" }, { "id": "MONDO:0011931", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011931", "name": "ovarian cancer, susceptibility to", "description": "" }, { "id": "MONDO:0011931", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011931", "name": "ovarian cancer, susceptibility to, 1", "description": "" }, { "id": "MIM:167000", "resource": "MIM", "url": "https://www.omim.org/entry/167000", "name": "Ovarian cancer", "description": "Ovarian cancer" } ], "unlinked_id_list": [ "DOID:2151" ], "evidence": [ { "id": "2394", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2394" } ] }, { "disease_id": "DOID:2841", "recommended_name": { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing." }, "synonyms": [ { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "bronchial hyperreactivity", "description": "" }, { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "chronic obstructive asthma", "description": "" }, { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "chronic obstructive asthma with acute exacerbation", "description": "" }, { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "chronic obstructive asthma with status asthmaticus", "description": "" }, { "id": "MONDO:0010940", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010940", "name": "inherited susceptibility to asthma", "description": "" }, { "id": "MONDO:0010940", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010940", "name": "asthma, nocturnal, susceptibility to", "description": "" }, { "id": "MIM:600807", "resource": "MIM", "url": "https://www.omim.org/entry/600807", "name": "Asthma", "description": "Asthma" } ], "unlinked_id_list": [ "DOID:0080811", "DOID:0080819" ], "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ] }, { "disease_id": "DOID:2957", "recommended_name": { "id": "DOID:2957", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2957", "name": "pulmonary tuberculosis", "description": "A tuberculosis that is a contagious disease located_in lungs. The infection has_symptom fever, has_symptom cough, has_symptom difficulty in breathing, has_symptom inflammatory infiltrations, has_symptom formation of tubercles, has_symptom caseation, has_symptom pleural effusion, and has_symptom fibrosis." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "2957", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2957" } ] }, { "disease_id": "DOID:3068", "recommended_name": { "id": "DOID:3068", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3068", "name": "glioblastoma", "description": "A malignant astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derives_from multiple cell types including astrocytes and oligondroctyes." }, "synonyms": [ { "id": "DOID:3068", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3068", "name": "GBM", "description": "" }, { "id": "DOID:3068", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3068", "name": "adult glioblastoma multiforme", "description": "" }, { "id": "DOID:3068", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3068", "name": "grade IV adult Astrocytic tumor", "description": "" }, { "id": "DOID:3068", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3068", "name": "primary glioblastoma multiforme", "description": "" }, { "id": "DOID:3068", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3068", "name": "spongioblastoma multiforme", "description": "" }, { "id": "DOID:3068", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3068", "name": "glioblastoma multiforme", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "3068", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3068" } ] }, { "disease_id": "DOID:3082", "recommended_name": { "id": "DOID:3082", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3082", "name": "interstitial lung disease", "description": "A lung disease that is characterized by inflammation and altered lung interstitium compromising pulmonary function and often has_symptom shortness of breath, dyspnea, and/or cough." }, "synonyms": [ { "id": "DOID:3082", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3082", "name": "ILD", "description": "" }, { "id": "MONDO:0030608", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0030608", "name": "interstitial lung disease 1", "description": "An interstitial lung disease in which the cause of the disease is a variation in the SFTPA1 gene." }, { "id": "MONDO:0030608", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0030608", "name": "ILD1", "description": "" }, { "id": "MONDO:0030608", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0030608", "name": "interstitial lung disease 1", "description": "" }, { "id": "MIM:619611", "resource": "MIM", "url": "https://www.omim.org/entry/619611", "name": "Interstitial lung disease 1", "description": "Interstitial lung disease 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "3082", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3082" } ] }, { "disease_id": "DOID:3083", "recommended_name": { "id": "DOID:3083", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3083", "name": "chronic obstructive pulmonary disease", "description": "An obstructive lung disease that is a chronic and progressive disorder of small airways in the lungs and that is characterized by irreversible airflow obstruction, typically identified by reductions in quantitative spirometric indices, induced forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (less than 0.7 is diagnostic of COPD). Lung volume is increased and pulmonary hypertension may occur. The pathologic changes result in the disruption of the airflow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough and chest tightness. COPD is a consequence (an end result) of chronic bronchitis, emphysema or both." }, "synonyms": [ { "id": "DOID:3083", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3083", "name": "COLD", "description": "" }, { "id": "DOID:3083", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3083", "name": "COPD", "description": "" }, { "id": "DOID:3083", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3083", "name": "chronic obstructive airway disease", "description": "" }, { "id": "DOID:3083", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3083", "name": "chronic obstructive lung disease", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "chronic obstructive pulmonary disease", "description": "A chronic and progressive lung disorder characterized by the loss of elasticity of the bronchial tree and the air sacs, destruction of the air sacs wall, thickening of the bronchial wall, and mucous accumulation in the bronchial tree. The pathologic changes result in the disruption of the air flow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough, and chest tightness. The two main types of chronic obstructive pulmonary disease are chronic obstructive bronchitis and emphysema." }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "COLD", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "COPD", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "COPD, chronic obstructive pulmonary disease", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "chronic obstructive airways disease", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "chronic obstructive lung disease", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "chronic obstructive pulmonary disease (COPD)", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "chronic obstructive pulmonary disease, (COPD)", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "cold", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "cold (chronic obstructive lung disease)", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "disease (COPD), chronic obstructive", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "obstructive lung disease, chronic", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "obstructive pulmonary disease (COPD), chronic", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "pulmonary disease (COPD), chronic obstructive", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "3083", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3083" } ] }, { "disease_id": "DOID:3371", "recommended_name": { "id": "DOID:3371", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3371", "name": "chondrosarcoma", "description": "A bone sarcoma that has_material_basis_in cells derived from transformed cells that produce cartilage." }, "synonyms": [ { "id": "DOID:3371", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3371", "name": "Cartilaginous cancer", "description": "" }, { "id": "DOID:3371", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3371", "name": "chondrosarcoma of bone", "description": "" }, { "id": "DOID:3371", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3371", "name": "primary chondrosarcoma of the bone", "description": "" }, { "id": "MONDO:0008977", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008977", "name": "chondrosarcoma", "description": "A malignant cartilaginous matrix-producing mesenchymal neoplasm arising from the bone and soft tissue. It usually affects middle-aged to elderly adults. The pelvic bones, ribs, shoulder girdle, and long bones are the most common sites of involvement. Most chondrosarcomas arise de novo, but some may develop in a preexisting benign cartilaginous lesion." }, { "id": "MONDO:0008977", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008977", "name": "chondrosarcoma", "description": "" }, { "id": "MONDO:0008977", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008977", "name": "chondrosarcoma (disease)", "description": "" }, { "id": "MONDO:0008977", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008977", "name": "chondrosarcoma, malignant", "description": "" }, { "id": "MONDO:0008977", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008977", "name": "chondrosarcoma, somatic mutation", "description": "" }, { "id": "MONDO:0008977", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008977", "name": "chondrosarcoma of bone", "description": "" }, { "id": "MIM:215300", "resource": "MIM", "url": "https://www.omim.org/entry/215300", "name": "Chondrosarcoma", "description": "Chondrosarcoma" } ], "unlinked_id_list": [], "evidence": [ { "id": "3371", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3371" } ] }, { "disease_id": "DOID:3393", "recommended_name": { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "coronary artery disease", "description": "An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles." }, "synonyms": [ { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "CHD", "description": "" }, { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "Coronary disease", "description": "" }, { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "coronary arteriosclerosis", "description": "" }, { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "coronary heart disease", "description": "" }, { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "Ischemic Heart Disease", "description": "" }, { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "myocardial ischemia", "description": "" }, { "id": "MONDO:0010331", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010331", "name": "coronary heart disease, susceptibility to, 3", "description": "" }, { "id": "MONDO:0010331", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010331", "name": "coronary heart disease, susceptibility to, 3", "description": "" }, { "id": "MONDO:0010331", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010331", "name": "coronary heart disease, susceptibility to, type 3", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary heart disease, susceptibility to, 1", "description": "Any coronary artery disease in which the cause of the disease is a mutation in the CX3CR1 gene." }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "CX3CR1 coronary artery disease", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary artery disease caused by mutation in CX3CR1", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary artery disease, resistance to", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary heart disease, susceptibility to", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary heart disease, susceptibility to, 1", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary heart disease, susceptibility to, type 1", "description": "" }, { "id": "MONDO:0012009", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012009", "name": "coronary heart disease, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012009", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012009", "name": "coronary heart disease, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012009", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012009", "name": "coronary heart disease, susceptibility to, type 2", "description": "" }, { "id": "MONDO:0012010", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012010", "name": "coronary heart disease, susceptibility to, 4", "description": "" }, { "id": "MONDO:0012010", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012010", "name": "coronary heart disease, susceptibility to, 4", "description": "" }, { "id": "MONDO:0012010", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012010", "name": "coronary heart disease, susceptibility to, type 4", "description": "" }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "coronary artery disease, autosomal dominant, 1", "description": "Any coronary artery disease in which the cause of the disease is a mutation in the MEF2A gene." }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "MEF2A coronary artery disease", "description": "" }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "coronary artery disease caused by mutation in MEF2A", "description": "" }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "coronary artery disease, autosomal dominant, 1", "description": "" }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "coronary artery disease, autosomal dominant, type 1", "description": "" }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "ADCAD1", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "coronary artery disease, autosomal dominant 2", "description": "Any coronary artery disease in which the cause of the disease is a mutation in the LRP6 gene." }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "LRP6 coronary artery disease", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "coronary artery disease caused by mutation in LRP6", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "coronary artery disease, autosomal dominant 2", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "coronary artery disease, autosomal dominant type 2", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "coronary artery disease, autosomal dominant, 2", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "ADCAD2", "description": "" }, { "id": "MONDO:0012628", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012628", "name": "coronary heart disease, susceptibility to, 8", "description": "" }, { "id": "MONDO:0012628", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012628", "name": "CHDS8", "description": "" }, { "id": "MONDO:0012628", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012628", "name": "coronary heart disease, susceptibility to, 8", "description": "" }, { "id": "MONDO:0012788", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012788", "name": "coronary heart disease, susceptibility to, 9", "description": "" }, { "id": "MONDO:0012788", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012788", "name": "CHDS9", "description": "" }, { "id": "MONDO:0012788", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012788", "name": "coronary heart disease, susceptibility to, 9", "description": "" }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "hydatidiform mole, recurrent, 2", "description": "Any complete hydatidiform mole in which the cause of the disease is a mutation in the KHDC3L gene." }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "KHDC3L complete hydatidiform mole", "description": "" }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "complete hydatidiform mole caused by mutation in KHDC3L", "description": "" }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "hydatidiform Mole, recurrent, type 2", "description": "" }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "hydatidiform mole, recurrent, 2", "description": "" }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "HYDM2", "description": "" }, { "id": "MIM:608320", "resource": "MIM", "url": "https://www.omim.org/entry/608320", "name": "Coronary artery disease, autosomal dominant, 1", "description": "Coronary artery disease, autosomal dominant, 1" }, { "id": "MIM:610947", "resource": "MIM", "url": "https://www.omim.org/entry/610947", "name": "Coronary artery disease, autosomal dominant, 2", "description": "Coronary artery disease, autosomal dominant, 2" }, { "id": "MIM:614293", "resource": "MIM", "url": "https://www.omim.org/entry/614293", "name": "Hydatidiform mole, recurrent, 2", "description": "Hydatidiform mole, recurrent, 2" } ], "unlinked_id_list": [ "DOID:11840" ], "evidence": [ { "id": "3393", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3393" } ] }, { "disease_id": "DOID:3770", "recommended_name": { "id": "DOID:3770", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3770", "name": "pulmonary fibrosis", "description": "An interstitial lung disease that is characterized by destruction, scarring, and thickening of the interstitial lung tissues and progressive pulmonary function loss in a restrictive pattern, has_symptom progressive shortness of breath, fatigue, and chronic cough, possibly has_material_basis_in exposure to certain chemicals, autoimmune conditions, and radiation. It can be caused by inhaling hazardous chemicals, certain diseases, medication and genetics or unknown causes." }, "synonyms": [ { "id": "DOID:3770", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3770", "name": "Fibrosis of lung", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "3770", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3770" } ] }, { "disease_id": "DOID:3908", "recommended_name": { "id": "DOID:3908", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma." }, "synonyms": [ { "id": "DOID:3908", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3908", "name": "NSCLC", "description": "" }, { "id": "DOID:3908", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3908", "name": "Non-small cell lung cancer", "description": "" }, { "id": "DOID:3908", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3908", "name": "non-small cell lung carcinoma", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ] }, { "disease_id": "DOID:399", "recommended_name": { "id": "DOID:399", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:399", "name": "tuberculosis", "description": "A primary bacterial infectious disease that is located_in lungs, located_in lymph nodes, located_in pericardium, located_in brain, located_in pleura or located_in gastrointestinal tract, has_material_basis_in Mycobacterium tuberculosis, which is transmitted_by droplets released into the air when an infected person coughs or sneezes." }, "synonyms": [], "unlinked_id_list": [ "DOID:2149" ], "evidence": [ { "id": "399", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:399" } ] }, { "disease_id": "DOID:418", "recommended_name": { "id": "DOID:418", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:418", "name": "systemic scleroderma", "description": "A scleroderma that is characterized by fibrosis (or hardening) of the skin and major organs, as well as vascular alterations, and autoantibodies." }, "synonyms": [ { "id": "DOID:418", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:418", "name": "Scleroderma", "description": "" }, { "id": "DOID:418", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:418", "name": "Scleroderma syndrome", "description": "" }, { "id": "DOID:418", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:418", "name": "progressive systemic sclerosis", "description": "" }, { "id": "DOID:418", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:418", "name": "systemic sclerosis", "description": "" }, { "id": "MONDO:0008418", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008418", "name": "scleroderma, familial progressive", "description": "" }, { "id": "MONDO:0008418", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008418", "name": "scleroderma, familial progressive", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "418", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:418" } ] }, { "disease_id": "DOID:4481", "recommended_name": { "id": "DOID:4481", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4481", "name": "allergic rhinitis", "description": "A rhinitis that is an allergic inflammation and irritation of the nasal airways involving sneezing, runny nose, nasal congestion, itching and tearing of the eyes caused by exposure to an allergen such as pollen, dust, mold, animal dander and droppings of cockroaches or house dust mites." }, "synonyms": [ { "id": "DOID:4481", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4481", "name": "Non-seasonal allergic rhinitis", "description": "" }, { "id": "DOID:4481", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4481", "name": "Perenial allergic rhinitis", "description": "" }, { "id": "DOID:4481", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4481", "name": "atopic rhinitis", "description": "" }, { "id": "DOID:4481", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4481", "name": "hay fever", "description": "" }, { "id": "DOID:4481", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4481", "name": "pollenosis", "description": "" }, { "id": "DOID:4481", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4481", "name": "seasonal allergic rhinitis", "description": "" }, { "id": "MONDO:0100177", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0100177", "name": "allergic rhinitis, susceptibility to", "description": "An inherited susceptibility or predisposition to developing allergic rhinitis." }, { "id": "MONDO:0100177", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0100177", "name": "allergic rhinitis, susceptibility to", "description": "" }, { "id": "MIM:607154", "resource": "MIM", "url": "https://www.omim.org/entry/607154", "name": "Allergic rhinitis", "description": "Allergic rhinitis" } ], "unlinked_id_list": [], "evidence": [ { "id": "4481", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4481" } ] }, { "disease_id": "DOID:5419", "recommended_name": { "id": "DOID:5419", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness." }, "synonyms": [ { "id": "DOID:5419", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5419", "name": "schizophrenia-1", "description": "" }, { "id": "MONDO:0005090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005090", "name": "schizophrenia", "description": "A major psychotic disorder characterized by abnormalities in the perception or expression of reality. It affects the cognitive and psychomotor functions. Common clinical signs and symptoms include delusions, hallucinations, disorganized thinking, and retreat from reality." }, { "id": "MONDO:0005090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005090", "name": "schizophrenia 12", "description": "" }, { "id": "MONDO:0005090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005090", "name": "schizophrenia", "description": "" }, { "id": "MONDO:0005090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005090", "name": "schizophrenia (disease)", "description": "" }, { "id": "MONDO:0005090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005090", "name": "SCZD", "description": "" }, { "id": "MIM:181500", "resource": "MIM", "url": "https://www.omim.org/entry/181500", "name": "Schizophrenia", "description": "Schizophrenia" } ], "unlinked_id_list": [], "evidence": [ { "id": "5419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ] }, { "disease_id": "DOID:5844", "recommended_name": { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia." }, "synonyms": [ { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "Myocardial infarct", "description": "" }, { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "heart attack", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, type 2", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ] }, { "disease_id": "DOID:6000", "recommended_name": { "id": "DOID:6000", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:6000", "name": "congestive heart failure", "description": "A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body." }, "synonyms": [ { "id": "DOID:6000", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:6000", "name": "CHF", "description": "" }, { "id": "DOID:6000", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:6000", "name": "Cardiac Failure Congestive", "description": "" }, { "id": "DOID:6000", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:6000", "name": "Congestive heart disease", "description": "" }, { "id": "DOID:6000", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:6000", "name": "Weak heart", "description": "" } ], "unlinked_id_list": [ "DOID:12326" ], "evidence": [ { "id": "6000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6000" } ] }, { "disease_id": "DOID:7148", "recommended_name": { "id": "DOID:7148", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:7148", "name": "rheumatoid arthritis", "description": "An arthritis that is an autoimmune disease which attacks healthy cells and tissue located_in joint." }, "synonyms": [ { "id": "DOID:7148", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:7148", "name": "Arthritis or polyarthritis, rheumatic", "description": "" }, { "id": "DOID:7148", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:7148", "name": "atrophic Arthritis", "description": "" }, { "id": "MONDO:0008383", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008383", "name": "rheumatoid arthritis", "description": "A chronic, systemic autoimmune disorder characterized by inflammation in the synovial membranes and articular surfaces. It manifests primarily as a symmetric, erosive polyarthritis that spares the axial skeleton and is typically associated with the presence in the serum of rheumatoid factor." }, { "id": "MONDO:0008383", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008383", "name": "RA", "description": "" }, { "id": "MONDO:0008383", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008383", "name": "rheumatoid arthritis", "description": "" }, { "id": "MIM:180300", "resource": "MIM", "url": "https://www.omim.org/entry/180300", "name": "Rheumatoid arthritis", "description": "Rheumatoid arthritis" } ], "unlinked_id_list": [], "evidence": [ { "id": "7148", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7148" } ] }, { "disease_id": "DOID:8869", "recommended_name": { "id": "DOID:8869", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8869", "name": "neuromyelitis optica", "description": "A central nervous system disease characterized by inflammation of the optic nerve (optic neuritis) and inflammation of the spinal cord (myelitis)." }, "synonyms": [ { "id": "DOID:8869", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8869", "name": "Devic's disease", "description": "" }, { "id": "DOID:8869", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8869", "name": "Devic's syndrome", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "8869", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8869" } ] }, { "disease_id": "DOID:9119", "recommended_name": { "id": "DOID:9119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9119", "name": "acute myeloid leukemia", "description": "A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells." }, "synonyms": [ { "id": "DOID:9119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9119", "name": "AML - acute Myeloid Leukemia", "description": "" }, { "id": "DOID:9119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9119", "name": "Leukemia, Myelocytic, acute", "description": "" }, { "id": "DOID:9119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9119", "name": "acute myeloblastic leukaemia", "description": "" }, { "id": "DOID:9119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9119", "name": "acute myeloblastic leukemia", "description": "" }, { "id": "DOID:9119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9119", "name": "acute myelogenous leukaemia", "description": "" }, { "id": "DOID:9119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9119", "name": "acute myelogenous leukemia", "description": "" }, { "id": "DOID:9119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9119", "name": "acute myeloid leukaemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myeloid leukemia", "description": "Acute myeloid leukemia (AML) is a group of neoplasms arising from precursor cells committed to the myeloid cell-line differentiation. All of them are characterized by clonal expansion of myeloid blasts. AML manifests by fever, pallor, anemia, hemorrhages and recurrent infections." }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "AML", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "AML - acute myeloid leukaemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "AML - acute myeloid leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "ANLL", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute Nonlymphocytic leukaemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute Nonlymphocytic leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute granulocytic leukaemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute granulocytic leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myeloblastic leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myelocytic leukaemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myelocytic leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myelogenous leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myelogenous leukemias", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myeloid leukaemia (AML)", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myeloid leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myeloid leukemia (AML)", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myeloid leukemia, somatic", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute nonlymphocytic leukaemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute nonlymphocytic leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "hematopoeitic - acute Myleogenous leukaemia (AML)", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "hematopoeitic - acute Myleogenous leukemia (AML)", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "leukemia, acute myeloid, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "leukemia, acute myeloid, reduced survival in, somatic", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "leukemia, acute myeloid, somatic", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "leukemia, acute myeloid, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "leukemia, myelocytic, acute", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "myeloid leukemia, acute", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "myeloid leukemia, acute, M4/M4Eo subtype, somatic", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute non lymphoblastic leukaemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute non lymphoblastic leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "leukemia, acute myeloid", "description": "" }, { "id": "MIM:601626", "resource": "MIM", "url": "https://www.omim.org/entry/601626", "name": "Leukemia, acute myelogenous", "description": "Leukemia, acute myelogenous" } ], "unlinked_id_list": [], "evidence": [ { "id": "9119", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9119" } ] }, { "disease_id": "DOID:9352", "recommended_name": { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin." }, "synonyms": [ { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "NIDDM", "description": "" }, { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "non-insulin-dependent diabetes mellitus", "description": "" }, { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "type 2 diabetes", "description": "" }, { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "type II diabetes mellitus", "description": "" }, { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "insulin resistance", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type 2 diabetes mellitus", "description": "A type of diabetes mellitus that is characterized by insulin resistance or desensitization and increased blood glucose levels. This is a chronic disease that can develop gradually over the life of a patient and can be linked to both environmental factors and heredity." }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "NIDDM", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "T2D", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "T2DM", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "T2DM - type 2 diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "adult onset diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "adult-onset diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitis type 2", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitis type II", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent, association with", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent, late onset", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, type 2", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, type II", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes, type 2", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "insulin resistance, severe, digenic", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "non-insulin dependent diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "non-insulin dependent diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "noninsulin dependent diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "noninsulin-dependent diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type 2 diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type 2 diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type 2 diabetes mellitus non-insulin dependent", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type II diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type II diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent, 2", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "diabetes mellitus, noninsulin-dependent, 1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "diabetes mellitus, noninsulin-dependent 1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "diabetes mellitus, noninsulin-dependent, 1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "diabetes mellitus, noninsulin-dependent, type 1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "NIDDM1", "description": "" }, { "id": "MONDO:0011072", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011072", "name": "diabetes mellitus, noninsulin-dependent, 2", "description": "" }, { "id": "MONDO:0011072", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011072", "name": "NIDDM2", "description": "" }, { "id": "MONDO:0011072", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011072", "name": "diabetes mellitus, noninsulin-dependent, 2", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "diabetes mellitus, noninsulin-dependent, 3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "diabetes mellitus, noninsulin-dependent, 3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "diabetes mellitus, noninsulin-dependent, type 3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "type 2 diabetes mellitus 3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "NIDDM3", "description": "" }, { "id": "MONDO:0011955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011955", "name": "diabetes mellitus, noninsulin-dependent, 4", "description": "" }, { "id": "MONDO:0011955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011955", "name": "diabetes mellitus, noninsulin-dependent, 4", "description": "" }, { "id": "MONDO:0011955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011955", "name": "diabetes mellitus, noninsulin-dependent, type 4", "description": "" }, { "id": "MIM:125853", "resource": "MIM", "url": "https://www.omim.org/entry/125853", "name": "Type 2 diabetes mellitus", "description": "Type 2 diabetes mellitus" }, { "id": "MIM:601283", "resource": "MIM", "url": "https://www.omim.org/entry/601283", "name": "Type 2 diabetes mellitus 1", "description": "Type 2 diabetes mellitus 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ] }, { "disease_id": "DOID:9360", "recommended_name": { "id": "DOID:9360", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9360", "name": "intrinsic asthma", "description": "A chronic asthma that is triggered by factors not attributable to allergies." }, "synonyms": [ { "id": "DOID:9360", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9360", "name": "non-atopic asthma", "description": "" } ], "unlinked_id_list": [ "DOID:0080819" ], "evidence": [ { "id": "9360", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9360" } ] }, { "disease_id": "DOID:9415", "recommended_name": { "id": "DOID:9415", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9415", "name": "allergic asthma", "description": "An extrinsic asthma that is characterized by symptoms that are triggered by an allergic reaction caused by inhaled allergens such as dust mite allergen, pet dander, pollen and mold. The disease has_symptom coughing, has_symptom wheezing, has_symptom shortness of breath or has_symptom rapid breathing, and has_symptom chest tightness." }, "synonyms": [ { "id": "DOID:9415", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9415", "name": "extrinsic asthma with acute exacerbation", "description": "" }, { "id": "DOID:9415", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9415", "name": "extrinsic asthma with status asthmaticus", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "9415", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9415" } ] }, { "disease_id": "DOID:9470", "recommended_name": { "id": "DOID:9470", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9470", "name": "bacterial meningitis", "description": "A meningitis that has_material_basis_in a bacterial infection." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "9470", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9470" } ] }, { "disease_id": "DOID:9538", "recommended_name": { "id": "DOID:9538", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9538", "name": "multiple myeloma", "description": "A myeloid neoplasm that is located_in the plasma cells in bone marrow." }, "synonyms": [ { "id": "DOID:9538", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9538", "name": "myeloma", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "plasma cell myeloma", "description": "A bone marrow-based plasma cell neoplasm characterized by a serum monoclonal protein and skeletal destruction with osteolytic lesions, pathological fractures, bone pain, hypercalcemia, and anemia. Clinical variants include non-secretory myeloma, smoldering myeloma, indolent myeloma, and plasma cell leukemia. (WHO, 2001)" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "Kahler disease", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "Kahler's disease", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "Multiple Myeloma", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "medullary plasmacytoma", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "multiple myeloma", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "multiple myeloma, resistance to, Somatic mutation", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "multiple myeloma, susceptibility to, Somatic mutation", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "multiple myeloma/plasma cell myeloma", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "myeloid neoplasm of plasma cell", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "myeloma", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "myeloma, multiple", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "myeloma, plasma cell, malignant", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "myelomatosis", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "plasma cell myeloid neoplasm", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "plasma cell myeloma", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "myeloma - multiple", "description": "" }, { "id": "MIM:254500", "resource": "MIM", "url": "https://www.omim.org/entry/254500", "name": "Multiple myeloma", "description": "Multiple myeloma" } ], "unlinked_id_list": [], "evidence": [ { "id": "9538", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9538" } ] }, { "disease_id": "DOID:9563", "recommended_name": { "id": "DOID:9563", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9563", "name": "bronchiectasis", "description": "A bronchial disease that is a chronic inflammatory condition of one or more bronchi or bronchioles marked by dilatation and loss of elasticity of the walls resulting from damage to the airway wall leading to the formation of small sacs on the bronchial wall and impairment of cilia mobility in the lung. Inflammation of the bronchial wall increases mucus secretion which serves as a breeding ground for bacteria. Bronchiectasis is caused by repeated respiratory infections, immune deficiency disorders, hereditary disorders (cystic fibrosis or primary ciliary dyskinesia), mechanical factors (inhaled object or a lung tumor) or inhaling toxic substances." }, "synonyms": [ { "id": "DOID:9563", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9563", "name": "Polynesian bronchiectasis", "description": "" }, { "id": "MONDO:0008887", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008887", "name": "bronchiectasis with or without elevated sweat chloride 1", "description": "" }, { "id": "MONDO:0008887", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008887", "name": "bronchiectasis with or without elevated sweat chloride 1", "description": "" }, { "id": "MONDO:0008887", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008887", "name": "bronchiectasis with or without elevated sweat chloride 1, modifier of", "description": "" }, { "id": "MONDO:0008887", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008887", "name": "bronchiectasis with or without elevated sweat chloride type 1", "description": "" }, { "id": "MONDO:0008887", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008887", "name": "BESC1", "description": "" }, { "id": "MIM:211400", "resource": "MIM", "url": "https://www.omim.org/entry/211400", "name": "Bronchiectasis with or without elevated sweat chloride 1", "description": "Bronchiectasis with or without elevated sweat chloride 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "9563", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9563" } ] }, { "disease_id": "DOID:9744", "recommended_name": { "id": "DOID:9744", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9744", "name": "type 1 diabetes mellitus", "description": "A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production." }, "synonyms": [ { "id": "DOID:9744", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9744", "name": "IDDM", "description": "" }, { "id": "DOID:9744", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9744", "name": "insulin-dependent diabetes mellitus", "description": "" }, { "id": "DOID:9744", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9744", "name": "type I diabetes mellitus", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "type 1 diabetes mellitus", "description": "A chronic condition characterized by minimal or absent production of insulin by the pancreas." }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "IDDM", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "T1D", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "T1DM", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "diabetes mellitis type 1", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "diabetes mellitis type I", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "immune mediated diabetes", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "insulin dependent diabetes", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "juvenile diabetes", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "type 1 diabetes", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "type I diabetes", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "type I diabetes mellitus", "description": "" }, { "id": "MIM:222100", "resource": "MIM", "url": "https://www.omim.org/entry/222100", "name": "Type 1 diabetes mellitus", "description": "Type 1 diabetes mellitus" } ], "unlinked_id_list": [], "evidence": [ { "id": "9744", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9744" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VZV2", "url": "https://www.uniprot.org/uniprotkb/Q9VZV2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Cht7", "url": "https://www.uniprot.org/uniprotkb/Q9VZV2", "locus": { "chromosome": "3L", "start_pos": 3090985, "end_pos": 3106958, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0035398", "url": "https://www.ensemblgenomes.org/id/FBgn0035398" } ] } } ], "crossref": [ { "id": "FB:FBgn0035398", "url": "https://alliancegenome.org/gene/FB:FBgn0035398", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0035398", "url": "https://bgee.org/?page=gene&gene_id=FBgn0035398", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02872", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02872", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0035398", "url": "https://flybase.org/reports/FBgn0035398", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "38370", "url": "https://www.ncbi.nlm.nih.gov/gene/38370", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001223", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001223", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001579", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001579", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002557", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002557", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011583", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011583", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029070", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029070", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036508", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036508", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG1869", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG1869", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YERMMTL", "url": "https://omabrowser.org/oma/group/YERMMTL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9VZV2", "url": "https://www.orthodb.org/?gene=Q9VZV2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11177", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11177", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11177:SF317", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11177:SF317", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00704", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00704", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01607", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01607", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-189085", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-189085", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_647768", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647768", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VZV2", "url": "https://www.uniprot.org/uniprotkb/Q9VZV2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VZV2-1", "url": "https://www.uniprot.org/uniprotkb/Q9VZV2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFPPRLLRIAFVICLLIVLLSPSADSAQTKTRRRLRRPTTSVSSSRSNLIESKKSTEAPEAEKRIDQITSATTTSARRTRLRSKAKLGAAAAGGAAVAAGGTALVASGSSLKGKKTKVDDGTPKIVCYYTNWSQYRVKIGKFVPEDIPADLCTHIIFAFGWLKKNKLSSYESNDETKDNVPGLYERMMTLKKANPKLKILLALGGWSFGTQKFKDMSSTRYTRQTFVYSAIPFLRKRGFDGLDMDWEYPKGSDDKKNFVLLLKELREAFEAEAQELKKPRLLLSAAVPVGPDNIRGGYDVPAIASYLDFINLMAYDFHGKWERETGHNAPLYAPSTDSEWRKQLSVDNAASLWVKMGAPKEKLVIGMPTYGRSFTLANPDKHGPNAPASGGGREGVYTKEGGFLAYYEICEMLLNGAVYVWDDEMKVPYLVDGDQWVGFDDERAIRNKMHWIKSNGFGGAMVWTIDMDDFKGEVCGGNVKYPLIGAMREELLGISRGKEAKDVNWTAVAATFEDIEEKPEPIKISVDEILNKVRKPQVQKKQRIKSGANAVASNTRPAQVFCYLTSWSAKRPGAGKFQPENIDPKLCTHIVYAFATLQDYKLTEATDDDPENYESVIALRDNNPDLQILLAIGGWAFGSTPFKELTSNVFRMNQFVYEAIDFLRDYKFNGLDVDWEYPRGAEDRVAYVSLLKELRVAFEGEAKSSGLPRLLLTAAVPASFEAIAAGYDVPEISKYLDFINVMTYDFHGQWERTVGHNSPLFALESATGYQKKLTVDYSAREWVKQGAPKEKLLIGMPTYGRSFELVNDTQFDIGSPSSGGGKAGKFTNEAGFLSYYEVCSFLAADNTTLVWDSEQQVPFAYRGNQWVGFDDERSLKTKTEWLKEQGFGGIMVWSIDMDDFSGRCGSGKYPLLTALNDELKDYKVELEYDGPYESHGPRGAYTTKDPHDVTCAEEDGHISYHKDWADCTHYYMCEGERKHHMPCPANLVFNPQENVCDWPENVEGCHTPTEAPA", "length": 1013, "header": "tr|Q9VZV2-1|Q9VZV2_DROME Isoform 1 of Chitinase 7 OS=Drosophila melanogaster OX=7227 GN=Cht7 PE=3 SV=3 CANONICAL=Q9VZV2-1" }, "isoforms": [ { "isoform_ac": "Q9VZV2-1", "url": "https://www.uniprot.org/uniprotkb/Q9VZV2/entry#Q9VZV2-1", "sequence": { "sequence": "MFPPRLLRIAFVICLLIVLLSPSADSAQTKTRRRLRRPTTSVSSSRSNLIESKKSTEAPEAEKRIDQITSATTTSARRTRLRSKAKLGAAAAGGAAVAAGGTALVASGSSLKGKKTKVDDGTPKIVCYYTNWSQYRVKIGKFVPEDIPADLCTHIIFAFGWLKKNKLSSYESNDETKDNVPGLYERMMTLKKANPKLKILLALGGWSFGTQKFKDMSSTRYTRQTFVYSAIPFLRKRGFDGLDMDWEYPKGSDDKKNFVLLLKELREAFEAEAQELKKPRLLLSAAVPVGPDNIRGGYDVPAIASYLDFINLMAYDFHGKWERETGHNAPLYAPSTDSEWRKQLSVDNAASLWVKMGAPKEKLVIGMPTYGRSFTLANPDKHGPNAPASGGGREGVYTKEGGFLAYYEICEMLLNGAVYVWDDEMKVPYLVDGDQWVGFDDERAIRNKMHWIKSNGFGGAMVWTIDMDDFKGEVCGGNVKYPLIGAMREELLGISRGKEAKDVNWTAVAATFEDIEEKPEPIKISVDEILNKVRKPQVQKKQRIKSGANAVASNTRPAQVFCYLTSWSAKRPGAGKFQPENIDPKLCTHIVYAFATLQDYKLTEATDDDPENYESVIALRDNNPDLQILLAIGGWAFGSTPFKELTSNVFRMNQFVYEAIDFLRDYKFNGLDVDWEYPRGAEDRVAYVSLLKELRVAFEGEAKSSGLPRLLLTAAVPASFEAIAAGYDVPEISKYLDFINVMTYDFHGQWERTVGHNSPLFALESATGYQKKLTVDYSAREWVKQGAPKEKLLIGMPTYGRSFELVNDTQFDIGSPSSGGGKAGKFTNEAGFLSYYEVCSFLAADNTTLVWDSEQQVPFAYRGNQWVGFDDERSLKTKTEWLKEQGFGGIMVWSIDMDDFSGRCGSGKYPLLTALNDELKDYKVELEYDGPYESHGPRGAYTTKDPHDVTCAEEDGHISYHKDWADCTHYYMCEGERKHHMPCPANLVFNPQENVCDWPENVEGCHTPTEAPA", "length": 1013, "header": "tr|Q9VZV2-1|Q9VZV2_DROME Isoform 1 of Chitinase 7 OS=Drosophila melanogaster OX=7227 GN=Cht7 PE=3 SV=3 CANONICAL=Q9VZV2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VZV2", "url": "https://www.uniprot.org/uniprotkb/Q9VZV2" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9VZV2", "url": "https://www.uniprot.org/uniprotkb/Q9VZV2" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZV2", "url": "https://www.uniprot.org/uniprotkb/Q9VZV2" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZV2", "url": "https://www.uniprot.org/uniprotkb/Q9VZV2" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VZV2", "url": "https://www.uniprot.org/uniprotkb/Q9VZV2" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9VZV2", "url": "https://www.uniprot.org/uniprotkb/Q9VZV2" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9VZV2", "url": "https://www.uniprot.org/uniprotkb/Q9VZV2" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZV2", "url": "https://www.uniprot.org/uniprotkb/Q9VZV2" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VZV2", "url": "https://www.uniprot.org/uniprotkb/Q9VZV2" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VZV2", "url": "https://www.uniprot.org/uniprotkb/Q9VZV2" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9VZV2", "url": "https://www.uniprot.org/uniprotkb/Q9VZV2" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG1869", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG1869", "resource": "KEGG Pathway" }, { "id": "R-DME-189085", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-189085", "resource": "Reactome", "description": "Digestion of dietary carbohydrate" }, { "id": "R-DME-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JDS2-1", "protein_name": "Chitinase-like 5", "gene_name": "Chil5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTKLILVTGLALLLNPQLGSAYQLMCYYNNVAQNRPKLGSFNPADIDPCLCTHLIYAFAGMQNNKVTMRSMNDLTDYQALNTLKSRNVQLKTLLAIGGRDFGPAPFSAMVSTPHNQQTFINSAIKFLRQYGFDGLNLDWQFPGSRGSPSRDKHLFTVLVQKIREAFELEAIENKSPRLMVTATVAGVISTIQSGYEIPQLSHFLDYIQVMTYNLHGSQDGYTGENSPLYKSLNDTGINTLLNVDYIMTYWNENGAAPEKLIVGFPAYGQTFTLSDPSNNGISAPTASAGTLGPYTEESGTWAYYEICSFLNDGATEAWDSAQEVPYAYQGNKWVGYDNVKSFRIKAEWLKQNNLGGAMLWTLDMDDFTGSFCNQGQFPLTSTLKNALLVYSTSCMASVSDLQQVNAPLYSGNRNWKRGSKAMDSVSPVPRE", "length": 431 }, "evidence": [ { "id": "MGI:2676649", "url": "https://alliancegenome.org/gene/MGI:2676649#orthology", "database": "AGR" }, { "id": "HGNC:17432", "url": "https://alliancegenome.org/gene/HGNC:17432#orthology", "database": "AGR" }, { "id": "FB:FBgn0035398", "url": "https://alliancegenome.org/gene/FB:FBgn0035398#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A8M1P3P0-1", "protein_name": "Histidine-rich carboxyl terminus protein 1 precursor", "gene_name": "si:ch211-226m16.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MHISRAFAFLCLVVSVGAQRTQSRLSCYLDVLTPHTREGSCTHIILPSVSSDDELYLQSLTENEYDAIQRMKERNSALKILLGLEIKSSRLKLMSANEASVGSFIQTLLTYLKEKRLDGLDVIWLDGTPSDTELFTDFLKSIKGVFEEEMRPLLLSASVKEPTDKTVASYDEQILSQYVDFISILPAQLQTDGQYISKTAQHWQDKQVDLQKLGLVMPGFLQRSRHRHHHRNHPKHDDTTAEEGKKDHVHLLNLYLGDQVCQAVKSGQLQFITLTSVSDEQSPIKEVLQQGFGGIGVVLIDLDVFGNSMCPNMTQKERATVESKAIMHSHHGHRRHGHGDHRHHHTGHHTRHHTRHHDRHHGRHHHGRHHHGHRPHHHGHRHHGRHHHHHHHHSTTTQSSVTQVTPKGME", "length": 410 }, "evidence": [ { "id": "MGI:1340899", "url": "https://alliancegenome.org/gene/MGI:1340899#orthology", "database": "AGR" }, { "id": "HGNC:1932", "url": "https://alliancegenome.org/gene/HGNC:1932#orthology", "database": "AGR" }, { "id": "HGNC:1933", "url": "https://alliancegenome.org/gene/HGNC:1933#orthology", "database": "AGR" }, { "id": "RGD:620874", "url": "https://alliancegenome.org/gene/RGD:620874#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58GSW9-1", "protein_name": "Chitinase-3-like protein 1 isoform X1", "gene_name": "ovgp1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MIWTCSSNKMNRGITHLIGLNLLFQFVACSKLVCYFTNWSQYRSGTARYLPENVDPNLCTHLIYAFAIINYANNIAGSEWNDVVHYSTFNALKKRNPQLITLLSVRDQDSSQFSIMLSKWINRQTFIKSSIEFLRKYNFDGLDLDWEMKNTSEMHPEDKLKFTLLCKELLEAFVAESLNSDTRLILTATVSAQKDVIERSYIIPEISEYLDFINVKTFDFHTYKDGIARHHSALYSAMSDDKDIKSNTDFALQYWRSQGAPAEKLLMGFSTYGRSFILNSSQNGVGAPANKFASPGPHTQEIGLWAYYEICLFLNGGVVQWIEDQKVPFSVKGNDWVGFDSLRSFNIKTKYLLEHGFGGAFVWALDLDDFSGYFCGQGTYPLVNSLKKSLIHGIESSSSMTSTNFFFSIFATAGKGSLPTPICVKIVRSFSAQQSLFCANRSDGLYYRTNSLNSFYSCSEGITNITWCTPFHAISNNSRKVQLSLMIIFITLGSAGFLTKMLI", "length": 503 }, "evidence": [ { "id": "MGI:106661", "url": "https://alliancegenome.org/gene/MGI:106661#orthology", "database": "AGR" }, { "id": "HGNC:8524", "url": "https://alliancegenome.org/gene/HGNC:8524#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-140106-118", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140106-118#orthology", "database": "AGR" }, { "id": "FB:FBgn0035398", "url": "https://alliancegenome.org/gene/FB:FBgn0035398#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D4A2D4-1", "protein_name": "Chitinase acidic-like 1", "gene_name": "Chial1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLYKTSEDPAGSVLRAFISKLVFIMGLNLLLNVQLDSAYQLMCYFNNWPQYQPDVRGMKLDDIDPCLCTHLIYSFAGIWENNNTMTKRKDLDDYKEFNDLKKRNNKLKTLLSIGCWNFEAGLFITMVSTPESRHTFITSVRKFLRKYGFDGLNLAWQYPGCYGSPPKDKHLFTILTQEIRKAFEKEVSKNKKSRLIITAALAGVISPIQFGYHVPQLSQSLDYIQVMTYDLHGSWDGYTGENSPLYKSPAETGVKAFYNIKYTMHNWKNKGVSPEKLIVGFPAYGHTFILSDSTKTEIGAPSNRGGHPGPYTKKTGFWAYYEICAFLKNGAIQVWNAAQQVPYAFHGNEWVGYDNVKSFHIKAQWLKNNNFGGAMIWAIGMDDYTGSFCDQGPFPLTSTLKNALKVHSASCKVTALSANVTGSRDSNFGALEPLFQLSSK", "length": 440 }, "evidence": [ { "id": "HGNC:17432", "url": "https://alliancegenome.org/gene/HGNC:17432#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M559-1", "protein_name": "Chitinase 3-like 3", "gene_name": "Chi3l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKLILATGLAILLYAHLGSSYQLMCYYTSWAKDRPTVGSFKIGNIDPCLCTHLIYAFAGMRNNEIINTSEQDLIDYEAINYLKDRNTELKTLLAIGGWKFGSAPFSAMVSTPQNRQTFIKSVIKFLRQYKFDGLNLDWQYPGSRGSPPKDKHLFSVLVQEMRKAFEKESTEQEIPRLLLTATVAGVIDTIQSGYKIPELSQSLDYFQVMTYNLHDFQNGYTRENSPLYQSPSDTGIYAYLNVDAIISYWKDNGAAREKLIVGFPAYGHNFILSDPSNTGINAPIVSTGPPGKFTGEAGLWAYYEICTFLNDGATDLWDGPQEVPYAVQGNVWVGYDNVKSFKIKAQWLKDNKLGGAMVWPLDMDDFTGSFCQQGRFPLTSTLKHYLGVQSTNCMAYKEEL", "length": 401 }, "evidence": [ { "id": "MGI:1330860", "url": "https://alliancegenome.org/gene/MGI:1330860#orthology", "database": "AGR" }, { "id": "MGI:1341098", "url": "https://alliancegenome.org/gene/MGI:1341098#orthology", "database": "AGR" }, { "id": "HGNC:17432", "url": "https://alliancegenome.org/gene/HGNC:17432#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O35744-1", "protein_name": "Chitinase-like protein 3", "gene_name": "Chil3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKLILVTGLAILLNVQLGSSYQLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEITYTHEQDLRDYEALNGLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQYPGSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELSQSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKLIVGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNEGATEVWDAPQEVPYAYQGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSGSFCHQRHFPLTSTLKGDLNIHSASCKGPY", "length": 398 }, "evidence": [ { "id": "MGI:1330860", "url": "https://alliancegenome.org/gene/MGI:1330860#orthology", "database": "AGR" }, { "id": "HGNC:17432", "url": "https://alliancegenome.org/gene/HGNC:17432#orthology", "database": "AGR" }, { "id": "FB:FBgn0035398", "url": "https://alliancegenome.org/gene/FB:FBgn0035398#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P36222-1", "protein_name": "Chitinase-3-like protein 1", "gene_name": "CHI3L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGVKASQTGFVVLVLLQCCSAYKLVCYYTSWSQYREGDGSCFPDALDRFLCTHIIYSFANISNDHIDTWEWNDVTLYGMLNTLKNRNPNLKTLLSVGGWNFGSQRFSKIASNTQSRRTFIKSVPPFLRTHGFDGLDLAWLYPGRRDKQHFTTLIKEMKAEFIKEAQPGKKQLLLSAALSAGKVTIDSSYDIAKISQHLDFISIMTYDFHGAWRGTTGHHSPLFRGQEDASPDRFSNTDYAVGYMLRLGAPASKLVMGIPTFGRSFTLASSETGVGAPISGPGIPGRFTKEAGTLAYYEICDFLRGATVHRILGQQVPYATKGNQWVGYDDQESVKSKVQYLKDRQLAGAMVWALDLDDFQGSFCGQDLRFPLTNAIKDALAAT", "length": 383 }, "evidence": [ { "id": "MGI:1340899", "url": "https://alliancegenome.org/gene/MGI:1340899#orthology", "database": "AGR" }, { "id": "HGNC:1932", "url": "https://alliancegenome.org/gene/HGNC:1932#orthology", "database": "AGR" }, { "id": "FB:FBgn0035398", "url": "https://alliancegenome.org/gene/FB:FBgn0035398#orthology", "database": "AGR" }, { "id": "RGD:620874", "url": "https://alliancegenome.org/gene/RGD:620874#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q06350-1", "protein_name": "Sporulation-specific chitinase 2", "gene_name": "CTS2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVGHSAQHRSKSSLVSHLLILLIFITIIIEMCLYNKIFKNQRSDDIRDNFNNGGHRVPSNVQNHGTHIRDEAFISGVYYSNWSPYKPRFHFPHDINLKQVSHIYYAFFKINSRTGGIENTDSWSDLEMNLYKSLAIKNSELIKESSNNSVQNILPLGCIGELFYLKNTCSDKKFKVIMSIGGWSDSENFKIIIKDDKLLQNFVDSSVETMFRLGFDGIDLDWEFPGNNESEPRGYLKLVRMLRLKLNSLESQIFGKRTEDHFQLSIAAPAFKDKLFYLPITEIDQYVDYWNMMTYDYYGSWSETTGYHSNLFSETELNGNFAMHYMIDRFGVNSRKLVLGMAAYGRSFHIKDNKFEPFNQNTVLINKIFKGVGKPTKEIDKADGKEGIWPYKNLPKIGTIEQYDPKYVSAYCFDEKNSIFISYDNTKSVKTKAEYVTHNNLGGGFWWESCGEAYANESRSLINAFNEGLHFNVSSKPSIFQDVRVKKYYLNKYGDGGFLSPYLKHLDSRKQ", "length": 511 }, "evidence": [ { "id": "MGI:1340899", "url": "https://alliancegenome.org/gene/MGI:1340899#orthology", "database": "AGR" }, { "id": "MGI:106661", "url": "https://alliancegenome.org/gene/MGI:106661#orthology", "database": "AGR" }, { "id": "MGI:1919134", "url": "https://alliancegenome.org/gene/MGI:1919134#orthology", "database": "AGR" }, { "id": "MGI:2676649", "url": "https://alliancegenome.org/gene/MGI:2676649#orthology", "database": "AGR" }, { "id": "MGI:1330860", "url": "https://alliancegenome.org/gene/MGI:1330860#orthology", "database": "AGR" }, { "id": "MGI:1341098", "url": "https://alliancegenome.org/gene/MGI:1341098#orthology", "database": "AGR" }, { "id": "MGI:1932052", "url": "https://alliancegenome.org/gene/MGI:1932052#orthology", "database": "AGR" }, { "id": "HGNC:8524", "url": "https://alliancegenome.org/gene/HGNC:8524#orthology", "database": "AGR" }, { "id": "HGNC:1932", "url": "https://alliancegenome.org/gene/HGNC:1932#orthology", "database": "AGR" }, { "id": "HGNC:1936", "url": "https://alliancegenome.org/gene/HGNC:1936#orthology", "database": "AGR" }, { "id": "HGNC:17432", "url": "https://alliancegenome.org/gene/HGNC:17432#orthology", "database": "AGR" }, { "id": "HGNC:1933", "url": "https://alliancegenome.org/gene/HGNC:1933#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-140106-118", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140106-118#orthology", "database": "AGR" }, { "id": "FB:FBgn0035398", "url": "https://alliancegenome.org/gene/FB:FBgn0035398#orthology", "database": "AGR" }, { "id": "RGD:620874", "url": "https://alliancegenome.org/gene/RGD:620874#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q12889-1", "protein_name": "Oviduct-specific glycoprotein", "gene_name": "OVGP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWKLLLWVGLVLVLKHHDGAAHKLVCYFTNWAHSRPGPASILPHDLDPFLCTHLIFAFASMNNNQIVAKDLQDEKILYPEFNKLKERNRELKTLLSIGGWNFGTSRFTTMLSTFANREKFIASVISLLRTHDFDGLDLFFLYPGLRGSPMHDRWTFLFLIEELLFAFRKEALLTMRPRLLLSAAVSGVPHIVQTSYDVRFLGRLLDFINVLSYDLHGSWERFTGHNSPLFSLPEDPKSSAYAMNYWRKLGAPSEKLIMGIPTYGRTFRLLKASKNGLQARAIGPASPGKYTKQEGFLAYFEICSFVWGAKKHWIDYQYVPYANKGKEWVGYDNAISFSYKAWFIRREHFGGAMVWTLDMDDVRGTFCGTGPFPLVYVLNDILVRAEFSSTSLPQFWLSSAVNSSSTDPERLAVTTAWTTDSKILPPGGEAGVTEIHGKCENMTITPRGTTVTPTKETVSLGKHTVALGEKTEITGAMTMTSVGHQSMTPGEKALTPVGHQSVTTGQKTLTSVGYQSVTPGEKTLTPVGHQSVTPVSHQSVSPGGTTMTPVHFQTETLRQNTVAPRRKAVAREKVTVPSRNISVTPEGQTMPLRGENLTSEVGTHPRMGNLGLQMEAENRMMLSSSPVIQLPEQTPLAFDNRFVPIYGNHSSVNSVTPQTSPLSLKKEIPENSAVDEEA", "length": 678 }, "evidence": [ { "id": "MGI:106661", "url": "https://alliancegenome.org/gene/MGI:106661#orthology", "database": "AGR" }, { "id": "HGNC:8524", "url": "https://alliancegenome.org/gene/HGNC:8524#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-140106-118", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140106-118#orthology", "database": "AGR" }, { "id": "FB:FBgn0035398", "url": "https://alliancegenome.org/gene/FB:FBgn0035398#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q13231-1", "protein_name": "Chitotriosidase-1", "gene_name": "CHIT1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVRSVAWAGFMVLLMIPWGSAAKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWNDETLYQEFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYPGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLILGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSWKGATKQRIQDQKVPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQGRYPLIQTLRQELSLPYLPSGTPELEVPKPGQPSEPEHGPSPGQDTFCQGKADGLYPNPRERSSFYSCAAGRLFQQSCPTGLVFSNSCKCCTWN", "length": 466 }, "evidence": [ { "id": "MGI:1919134", "url": "https://alliancegenome.org/gene/MGI:1919134#orthology", "database": "AGR" }, { "id": "HGNC:1936", "url": "https://alliancegenome.org/gene/HGNC:1936#orthology", "database": "AGR" }, { "id": "FB:FBgn0035398", "url": "https://alliancegenome.org/gene/FB:FBgn0035398#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q15782-4", "protein_name": "Chitinase-3-like protein 2", "gene_name": "CHI3L2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGATTMDQKSLWAGVVVLLLLQGGSAYKLVCYFTNWSQDRQEPGKFTPENIDPFLCSHLIYSFASIENNKVIIKDKSEVMLYQTINSLKTKNPKLKILLSIGGYLFGSKGFHPMVDSSTSRLEFINSIILFLRNHNFDGLDVSWIYPDQKENTHFTVLIHELAEAFQKDFTKSTKERLLLTAGVSAGRQMIDNSYQVEKLAKDLDFINLLSFDFHGSWEKPLITGHNSPLSKGWQDRGPSSYYNVEYAVGYWIHKGMPSEKVVMGIPTYGHSFTLASAETTVGAPASGPGAAGPITESSGFLAYYEICQFLKGAKITRLQDQQVPYAVKGNQWVGYDDVKSMETKVQFLKNLNLGGAMIWSIDMDDFTGKSCNQGPYPLVQAVKRSLGSL", "length": 390 }, "evidence": [ { "id": "HGNC:1933", "url": "https://alliancegenome.org/gene/HGNC:1933#orthology", "database": "AGR" }, { "id": "FB:FBgn0035398", "url": "https://alliancegenome.org/gene/FB:FBgn0035398#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q23997-1", "protein_name": "Imaginal disk growth factor 6", "gene_name": "Idgf6", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MIIKALAIVSLCLASIQASKVGAPQLPKKHLVCYYDSASFVKEGLGKLVIDELEPALQFCDYLVYGYAGIERDSHKAVSLNQQLDLDLGKGLYRTVTRLKRKYPNVKILLSVGGDKDIELDKDAKELPNKYLELLESPTGRTRFVNTVYSLVKTYGFDGLDVAWQFPKNKPKKVHSGIGSLWKGFKKVFSGDSIVDEKSEEHKEQFTALLRDVKNAFRPDNLLLSTTVLPNVNSSLFYDIPAVVNYLDFVNLGTFDFFTPQRNPEVADYAAPIYELSERNPEFNVAAQVKYWLRNNCPASKINVGVATYGRPWKLTDDSGDTGVPPVKDVKDEAPVGGNTQVPGIYSWPEVCALLPNQNNAYLKGANAPLIKVQDPAKRFGSYAYRAADKKGDNGIWVSFEDPDTAADKAGYVRTENLGGVALFDLSYDDFRGLCTNEKYPILRAIKYRLTN", "length": 452 }, "evidence": [ { "id": "HGNC:1932", "url": "https://alliancegenome.org/gene/HGNC:1932#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-140106-118", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140106-118#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q61362-1", "protein_name": "Chitinase-3-like protein 1", "gene_name": "Chi3l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHTSTEARMGMRAALTGFAVLMLLQSCSAYKLVCYFTSWSQYREGVGSFLPDAIQPFLCTHIIYSFANISSDNMLSTWEWNDESNYDKLNKLKTRNTNLKTLLSVGGWKFGEKRFSEIASNTERRTAFVRSVAPFLRSYGFDGLDLAWLYPRLRDKQYFSTLIKELNAEFTKEVQPGREKLLLSAALSAGKVAIDTGYDIAQIAQHLDFINLMTYDFHGVWRQITGHHSPLFQGQKDTRFDRYSNVNYAVQYMIRLGAQASKLLMGIPTFGKSFTLASSENQLGAPISGEGLPGRFTKEAGTLAYYEICDFLKGAEVHRLSNEKVPFATKGNQWVGYEDKESVKNKVGFLKEKKLAGAMVWALDLDDFQGTCQPKEFFPLTNAIKDALA", "length": 389 }, "evidence": [ { "id": "MGI:1340899", "url": "https://alliancegenome.org/gene/MGI:1340899#orthology", "database": "AGR" }, { "id": "HGNC:1932", "url": "https://alliancegenome.org/gene/HGNC:1932#orthology", "database": "AGR" }, { "id": "FB:FBgn0035398", "url": "https://alliancegenome.org/gene/FB:FBgn0035398#orthology", "database": "AGR" }, { "id": "RGD:620874", "url": "https://alliancegenome.org/gene/RGD:620874#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q62010-1", "protein_name": "Oviduct-specific glycoprotein", "gene_name": "Ovgp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGRLLLLAGLVLLMKHSDGTAYKLVCYFTNWAHSRPGPASIMPHDLDPFLCTHLIFAFASMSNNQIVAKNLQDENVLYPEFNKLKERNRELKTLLSIGGWNFGTSRFTAMLSTLANREKFIDSVISFLRIHGFDGLDLFFLYPGLRGSPPHDRWNFLFLIEELQFAFEREALLTQHPRLLLSAAVSGIPSIIHTSYDALLLGRRLDFINVLSYDLHGSWEKFTGHNSPLFSLPEDSKSSAYAMNYWRKLGTPADKLIMGFPTYGRNFYLLKESKNGLQTASMGPASPGKYTKQAGFLAYYEVCSFVQRAKKHWIDYQYVPYAFKGKEWLGYDDTISFSYKAMYVKREHFGGAMVWTLDMDDVRGTFCGNGPFPLVHILNELLVQTESNSTPLPQFWFTSSVNASGPGSENTALTEVLTTDTIKILPPGGEAMTTEVHRRYENMTTVPSDGSVTPGGTASPRKHAVTPENNTMAAEAKTMSTLDFFSKTTTGVSKTTTGISKTTTGVSKTTTGVSKATAGISKTIPEISKATAGVSKTTTGVSKTTTGISKTITGVSKTTTGISKTTTGISKTTTGVSKITTGVSKTTTGISKTTTGISQTTTGISKTTTDISKTTTGISKTTPGISKTTPGMTVIVQTQANEAETTATMDHQSVTPTEMDTTLFYLKTMTPSEKETSRKKTMVLEKATVSPREMSATPNGQSKTLKWASLITEVETYSQDG", "length": 721 }, "evidence": [ { "id": "MGI:106661", "url": "https://alliancegenome.org/gene/MGI:106661#orthology", "database": "AGR" }, { "id": "HGNC:8524", "url": "https://alliancegenome.org/gene/HGNC:8524#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-140106-118", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140106-118#orthology", "database": "AGR" }, { "id": "FB:FBgn0035398", "url": "https://alliancegenome.org/gene/FB:FBgn0035398#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6RY07-1", "protein_name": "Acidic mammalian chitinase", "gene_name": "Chia", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKLILVTGLVLLLNVQLGSAYNLVCYFTNWAQYRPGLGSFKPDDINPCLCTHLIYAFAGMQNNQITTIEWNDVTLYKAFNDLKNRNSKLKTLLAIGGWNFGTAPFTTMVSTSQNRQTFITSVIKFLRQYGFDGLDLDWEYPGSRGSPPQDKHLFTVLVKELREAFEQEAIESNRPRLMVTAAVAAGISNIQAGYEIPELSQYLDFIHVMTYDLHGSWDGYTGENSPLYKLPTETGSNAYLNVDYVMNYWKDNGAPAEKLIVGFPEYGHTYILSNPSDTGIGAPTSGNGPAGPYTRQAGFWAYYEICTFLRNGATQDWDAPQEVPYAYKGNEWVGYDNIKSFSVKAQWLKQNNFGGAMIWAIDLDDFTGSFCDQGKFPLTSTLNKALDIPTAGCTAPDLPSEPVTTPPGSGSGGGSSGGGSEGSGFCAGKADGLYPVADDRNAFWHCINGITYQQHCQAGLVFDTSCNCCNWP", "length": 473 }, "evidence": [ { "id": "MGI:1932052", "url": "https://alliancegenome.org/gene/MGI:1932052#orthology", "database": "AGR" }, { "id": "HGNC:17432", "url": "https://alliancegenome.org/gene/HGNC:17432#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8MLW8-1", "protein_name": "3.2.1.14", "gene_name": "Cht12", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTSFQYVFMIMIFLICGCIAKEYNVFCQYDLGSYYYKGRSQFFEWHLDSRLCTHLVLGSGIGVDGDSGELRITDKILLLEKDKLSSVKTMKWDSIKKVMFTIGGWEEDSSSFSRMVASPKKRDNFYSSMLEFMFRWGFDGVQIDWRYPTLLGGHPDDRQNFVILLEELGLIFRKNQLILMVAVLGRRDNRILESYNIPEIVNHSDFIHLMMHDEQDPYHLRLAYNAPLVGYEGSVTDSIMHWKRNGGAPEKLILGIPLFVRSFTMDRNQSTVGSACKGPGRQTKQSHRPGFMTYNEWCVQQSKWSRMFDQLAKVPYATRGDQWVSYENPRSIWAKMHLLQEHKLGGAMAWTIDVDDFRGRCGEQHGLLRVIFSALGDKNGLTTEKPTTEASGLCPHDGFSRDGWDCRLYHECRDGERIYYECLEGQYFDENQIVCRPAAEVKCDQNFVIWRPGMPVYSYDNMPLNLKIVE", "length": 470 }, "evidence": [ { "id": "MGI:2676649", "url": "https://alliancegenome.org/gene/MGI:2676649#orthology", "database": "AGR" }, { "id": "MGI:1330860", "url": "https://alliancegenome.org/gene/MGI:1330860#orthology", "database": "AGR" }, { "id": "MGI:1341098", "url": "https://alliancegenome.org/gene/MGI:1341098#orthology", "database": "AGR" }, { "id": "MGI:1932052", "url": "https://alliancegenome.org/gene/MGI:1932052#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8MLZ7-1", "protein_name": "Chitinase-like protein Idgf3", "gene_name": "Idgf3", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTGSLWLSLALSLAVLAQFKVSAAPNLVCFYDSQGSQRQGLAQFSMIDIELALQFCTHLVYGYAGVNADNYEMQSINKRLDLEQRHLAQITSMKERYPHIKFLLSVGGDADTYEGNQYIKLLESGQQGHRRFIESARDLVRRYNFDGLDLALQLPRNKPRKVHGDVGSAWKSFKKFFTGDFIVDTESETHKGQVTALIKDLSAALKQNDLLLSLTVLPNVNSSWYYDAPSIAPSLDFINLGTFDFLTPQRNPEEADFSAPTYEAVGQNRLGHYNLNFQMEHWLLQRVPANKINIGIATYGRSWKMSKDSGDSGMPVVPSTQGPAPAGPQSKQEGLLNWAEICSLMPNPSNSNARGPNAPVKRVVDPTKRYGSYAFRAADENGDHGLWISYDDPDSASSKAMYARARNLGGVALFDLTQDDFRGQCTNDRFPMLRAIKYRLL", "length": 441 }, "evidence": [ { "id": "MGI:1919134", "url": "https://alliancegenome.org/gene/MGI:1919134#orthology", "database": "AGR" }, { "id": "HGNC:1932", "url": "https://alliancegenome.org/gene/HGNC:1932#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-140106-118", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140106-118#orthology", "database": "AGR" }, { "id": "RGD:620874", "url": "https://alliancegenome.org/gene/RGD:620874#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8MM24-1", "protein_name": "Chitinase-like protein Idgf1", "gene_name": "Idgf1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRFQLFYILGLLSVTSLTHAASNLICYYDSNSYLRQGLAKMHTNELDLALQFCTHLVYGYAGLKSGTLELFSLNVDLDMFYYKDITALRQKFPQLKILLSVGGDRDVDEAHPNKYVELLEANRTAQQNFIDSSMILLKRNGFDGLDLAFQLPRNKPRKVHGSLGSYWKSFKKLFTGDFVVDPQAEEHKSQFTDLVGNIKNAFRSANLMLSLTVLPNVNSTWYFDVPKLHPQFDYINLAAFDFLTPLRNPEEADFTAPIFFQDEQNRLPHLNVEFQINYWLQNHCPGQKLNLGIASYGRAWKLSKGSGLSGAPIVHETCGVAPGGIQIQSAEGLLSWPEICSKLSQNASAQYRGELAPLRKVTDLTQKYGNYALRPADDNGDFGVWLSFDDPDFAGIKAVYAKGKGLGGIALFDLSYDDFRGLCTGQKYPILRSIKYFMG", "length": 439 }, "evidence": [ { "id": "MGI:1919134", "url": "https://alliancegenome.org/gene/MGI:1919134#orthology", "database": "AGR" }, { "id": "HGNC:1932", "url": "https://alliancegenome.org/gene/HGNC:1932#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-140106-118", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140106-118#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8T0R7-1", "protein_name": "Chitinase-like protein Idgf5", "gene_name": "Idgf5", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MMWIQKNPFLGLLLCSFLAFFQSTYAEVGKLVCFYDAQSFVREGPAQMSLAELEPALQFCNFLVYGYAGIDAVTYKIKSLDPSLTNDRQHYRHITALRKKYPHVRFLLSVGGDRDVNSEGVADSDKYLRLLEQSEHRKSFQASVLAELNNNGFDGIDLAWQFPKNRPKLQQGVFKRVWGSLRGWFSSSSVDEKSEEHREQFATLLEELQSDLRRGGQLLTVSMLPHVSAELFIDVPKVLSNVDFVNLGTYDFQTPERDPKVADLPTPLYAMYDRDPSHNVQYQVQYWMNQTSEISVHKLHVGVTSYGRAWNMTRNSGITGYPPIPAANGAAPPGRQTVTPGLLSWPEICDLLQQQPQDREVPHLRKVGDPTKRFGIYAYRAADDQGENGLWVGYEDPLTAAIKAGFVHAQGLGGVAFHDLSMDDFRGQCAGEKFPILRSIKFKL", "length": 444 }, "evidence": [ { "id": "HGNC:1932", "url": "https://alliancegenome.org/gene/HGNC:1932#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-140106-118", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140106-118#orthology", "database": "AGR" }, { "id": "RGD:620874", "url": "https://alliancegenome.org/gene/RGD:620874#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q91XA9-1", "protein_name": "Acidic mammalian chitinase", "gene_name": "Chia", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKLLLVTGLALLLNAQLGSAYNLICYFTNWAQYRPGLGSFKPDDINPCLCTHLIYAFAGMQNNEITTIEWNDVTLYKAFNDLKNRNSKLKTLLAIGGWNFGTAPFTTMVSTSQNRQTFITSVIKFLRQYGFDGLDLDWEYPGSRGSPPQDKHLFTVLVKEMREAFEQEAIESNRPRLMVTAAVAGGISNIQAGYEIPELSKYLDFIHVMTYDLHGSWEGYTGENSPLYKYPTETGSNAYLNVDYVMNYWKNNGAPAEKLIVGFPEYGHTFILRNPSDNGIGAPTSGDGPAGPYTRQAGFWAYYEICTFLRSGATEVWDASQEVPYAYKANEWLGYDNIKSFSVKAQWLKQNNFGGAMIWAIDLDDFTGSFCDQGKFPLTSTLNKALGISTEGCTAPDVPSEPVTTPPGSGSGGGSSGGSSGGSGFCADKADGLYPVADDRNAFWQCINGITYQQHCQAGLVFDTSCNCCNWP", "length": 473 }, "evidence": [ { "id": "MGI:1932052", "url": "https://alliancegenome.org/gene/MGI:1932052#orthology", "database": "AGR" }, { "id": "HGNC:17432", "url": "https://alliancegenome.org/gene/HGNC:17432#orthology", "database": "AGR" }, { "id": "FB:FBgn0035398", "url": "https://alliancegenome.org/gene/FB:FBgn0035398#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q91Z98-1", "protein_name": "Chitinase-like protein 4", "gene_name": "Chil4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKLILVTGLAILLNVQLGSSYQLMCYYTSWAKDRPTEGSFKPGNIDPCLCTHLIYAFAGMKNNEITYLSEQDLRDYEALNGLKDRNTELKTLLAIGGWKFGPAPFSSMVSTPQNRQTFIKSVIRFLRQYNFDGLNLDWQYPGSRGSPPKDKHLFSVLVQEMRKAFEEESTLNHIPRLLLTSTGAGFIDVIKSGYKIPELSQSLDYIQVMTYDLHDPKNGYTGENSPLYKSPYDIGKSADLNVDSIITYWKDHGAASEKLIVGFPAYGHTFILSDPSKNGIGDPTVSAGPPGKYTNEQGLLAYFEICTFLNEGATEIFDATQEVPYAYLGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSGSFCHQGRFPLTTTLKRDLNVHSASCKASYRGEL", "length": 402 }, "evidence": [ { "id": "MGI:1341098", "url": "https://alliancegenome.org/gene/MGI:1341098#orthology", "database": "AGR" }, { "id": "HGNC:17432", "url": "https://alliancegenome.org/gene/HGNC:17432#orthology", "database": "AGR" }, { "id": "FB:FBgn0035398", "url": "https://alliancegenome.org/gene/FB:FBgn0035398#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BZP6-1", "protein_name": "Acidic mammalian chitinase", "gene_name": "CHIA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTKLILLTGLVLILNLQLGSAYQLTCYFTNWAQYRPGLGRFMPDNIDPCLCTHLIYAFAGRQNNEITTIEWNDVTLYQAFNGLKNKNSQLKTLLAIGGWNFGTAPFTAMVSTPENRQTFITSVIKFLRQYEFDGLDFDWEYPGSRGSPPQDKHLFTVLVQEMREAFEQEAKQINKPRLMVTAAVAAGISNIQSGYEIPQLSQYLDYIHVMTYDLHGSWEGYTGENSPLYKYPTDTGSNAYLNVDYVMNYWKDNGAPAEKLIVGFPTYGHNFILSNPSNTGIGAPTSGAGPAGPYAKESGIWAYYEICTFLKNGATQGWDAPQEVPYAYQGNVWVGYDNIKSFDIKAQWLKHNKFGGAMVWAIDLDDFTGTFCNQGKFPLISTLKKALGLQSASCTAPAQPIEPITAAPSGSGNGSGSSSSGGSSGGSGFCAVRANGLYPVANNRNAFWHCVNGVTYQQNCQAGLVFDTSCDCCNWA", "length": 476 }, "evidence": [ { "id": "MGI:2676649", "url": "https://alliancegenome.org/gene/MGI:2676649#orthology", "database": "AGR" }, { "id": "MGI:1330860", "url": "https://alliancegenome.org/gene/MGI:1330860#orthology", "database": "AGR" }, { "id": "MGI:1341098", "url": "https://alliancegenome.org/gene/MGI:1341098#orthology", "database": "AGR" }, { "id": "MGI:1932052", "url": "https://alliancegenome.org/gene/MGI:1932052#orthology", "database": "AGR" }, { "id": "HGNC:17432", "url": "https://alliancegenome.org/gene/HGNC:17432#orthology", "database": "AGR" }, { "id": "FB:FBgn0035398", "url": "https://alliancegenome.org/gene/FB:FBgn0035398#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D7Q1-1", "protein_name": "Chitotriosidase-1", "gene_name": "Chit1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVQSLAWAGVMTLLMVQWGSAAKLVCYLTNWSQYRTEAVRFFPRDVDPNLCTHVIFAFAGMDNHQLSTVEHNDELLYQELNSLKTKNPKLKTLLAVGGWTFGTQKFTDMVATASNRQTFVKSALSFLRTQGFDGLDLDWEFPGGRGSPTVDKERFTALIQDLAKAFQEEAQSSGKERLLLTAAVPSDRGLVDAGYEVDKIAQSLDFINLMAYDFHSSLEKTTGHNSPLYKRQGESGAAAEQNVDAAVTLWLQKGTPASKLILGMPTYGRSFTLASSSDNGVGAPATGPGAPGPYTKDKGVLAYYEACSWKERHRIEDQKVPYAFQDNQWVSFDDVESFKAKAAYLKQKGLGGAMVWVLDLDDFKGSFCNQGPYPLIRTLRQELNLPSETPRSPEQIIPEPRPSSMPEQGPSPGLDNFCQGKADGVYPNPGDESTYYNCGGGRLFQQSCPPGLVFRASCKCCTWS", "length": 464 }, "evidence": [ { "id": "MGI:1919134", "url": "https://alliancegenome.org/gene/MGI:1919134#orthology", "database": "AGR" }, { "id": "HGNC:1936", "url": "https://alliancegenome.org/gene/HGNC:1936#orthology", "database": "AGR" }, { "id": "FB:FBgn0035398", "url": "https://alliancegenome.org/gene/FB:FBgn0035398#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9V3D4-1", "protein_name": "Chitinase-like protein Idgf2", "gene_name": "Idgf2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKAWIWFTFVACLFAASTEAASNLVCYYDSSSYTREGLGKLLNPDLEIALQFCSHLVYGYAGLRGENLQAYSMNENLDIYKHQFSEVTSLKRKYPHLKVLLSVGGDHDIDPDHPNKYIDLLEGEKVRQIGFIRSAYDLVKTYGFDGLDLAYQFPKNKPRKVHGDLGLAWKSIKKLFTGDFIVDPHAALHKEQFTALVRDVKDSLRADGFLLSLTVLPNVNSTWYFDIPALNGLVDFVNLATFDFLTPARNPEEADYSAPIYHPDGSKDRLAHLNADFQVEYWLSQGFPSNKINLGVATYGNAWKLTKDSGLEGVPVVPETSGPAPEGFQSQKPGLLSYAEICGKLSNPQNQFLKGNESPLRRVSDPTKRFGGIAYRPVDGQITEGIWVSYDDPDSASNKAAYARVKNLGGVALFDLSYDDFRGQCSGDKYPILRAIKYRL", "length": 440 }, "evidence": [ { "id": "MGI:1919134", "url": "https://alliancegenome.org/gene/MGI:1919134#orthology", "database": "AGR" }, { "id": "HGNC:1932", "url": "https://alliancegenome.org/gene/HGNC:1932#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-140106-118", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140106-118#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VFR3-1", "protein_name": "chitinase", "gene_name": "Cht5", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVRYIPLLLLGVLCSWPAATVASDQASRIVCYFSNWAVYRTGIGRYGLEDVPADLCTHIIYSFIGVNDKSWDVLVIDPELDVDQGGFSKFTQLKKSNPNVKLEIAVGGWAEGGSKYSQMVAVRDRRQSFIRSVVRFMKQYNFDGFDLDWEYPGATDRGGNYGDKDKFLYFVEELRRAFDREGRGWEITMAVPVAKFRLNEGYHVPELCEALDAIHAMTYDLRGNWAGFADVHSPLYKRKHDQYAYEKLNVNDGLALWEEMGCPANKLVVGVPFYGRTFTLSNSNKNYNMGTYINKEAGGGAPGPYTNASGFLAYYEICTEVMDKSKGWTVEWDDAGMVPYTYKDTQWVGYENEASIQIKMDFIKQRGYAGAMTWAIDMDDFHGMCGRKNGLTQILYDNMKNYRVPEPTRQTTPRPEWAKPPATPPNPDEGAVVAPTTSTTKRPKPKPKPTSSPLSPTSAPGPVPTVGSSTPKPTTKKPKKPKKTTTTTTTTPAPEKSTEEPEEVVYPVDPVEPTDPEQPMGPQFDPNEIDCTNRDFVPHPNCRKYFRCVHGKPVEFECKEGTAFHTVLNVCDWIENSDRYYCSRMKNKEKGNEAH", "length": 595 }, "evidence": [ { "id": "MGI:2676649", "url": "https://alliancegenome.org/gene/MGI:2676649#orthology", "database": "AGR" }, { "id": "MGI:1330860", "url": "https://alliancegenome.org/gene/MGI:1330860#orthology", "database": "AGR" }, { "id": "MGI:1341098", "url": "https://alliancegenome.org/gene/MGI:1341098#orthology", "database": "AGR" }, { "id": "MGI:1932052", "url": "https://alliancegenome.org/gene/MGI:1932052#orthology", "database": "AGR" }, { "id": "HGNC:17432", "url": "https://alliancegenome.org/gene/HGNC:17432#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W092-1", "protein_name": "Probable chitinase 2", "gene_name": "Cht2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTLRSRLSGEAPQLWLLLLLASTASSLWASVAARTGPLHDKVVVCYVSTWAVYRPEQGAYAIENFDPNLCTHVVYAFAGLDITQAAIKSLDPWQDLKEEYGKGGYEKMTGLKRSHPHLKVSLAIGGWNEGSANYSTLVANNLLRGRFVKQVSSFIRKYNFDGLDLDWEYPTQRKGKPADRENFVLLTKELREEFDEHGLLLTSAIGASKKVIDEAYDVRQISRYLDYLHIMCYDYHGSWDRRVGYNAPLTAPADDPLSVKFSIDYLLKLGAPPEKLVMGLPFYGRTFKTLASGFLNDVSEGVGFKGPYTREDGFLGYNEICQTLSNQTSGWTREWDPQTSQVLAKSERNVFTQEINVVTYDSSRSIANKVLFAMSKRLAGVMVWSVDTDDFLGNCKLDEDTYEDFQKVTAAPKRSSQNYPLLRTINEATMLAVDELAVPEPQPDDSENEIPHGSIADRKNAGASMVSLGLGVTAVFMLLHRLAQ", "length": 484 }, "evidence": [ { "id": "MGI:2676649", "url": "https://alliancegenome.org/gene/MGI:2676649#orthology", "database": "AGR" }, { "id": "MGI:1330860", "url": "https://alliancegenome.org/gene/MGI:1330860#orthology", "database": "AGR" }, { "id": "MGI:1341098", "url": "https://alliancegenome.org/gene/MGI:1341098#orthology", "database": "AGR" }, { "id": "MGI:1932052", "url": "https://alliancegenome.org/gene/MGI:1932052#orthology", "database": "AGR" }, { "id": "HGNC:17432", "url": "https://alliancegenome.org/gene/HGNC:17432#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-140106-118", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140106-118#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W2M5-1", "protein_name": "3.2.1.14", "gene_name": "Cht9", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGKLLALLAVLCLSQVIGAERIVNCYWGTWANYRSGNGKFDVSNIDAGLCTHLSYSFFGINDNGEIQSLDTWLDYDLGFINQAISLKNQNSNLKVLAVVGGWNEGSTKYSSMSGDWYKRQNFINSALNLLRNHGFDGLDLDWEYPNQRGGNWNDRANFVTLLREIKEAFAPYGYELGIAVGAGESLASASYEIANIAQQVDFINVMTYDFAMASDGQTGFNAPQWAVENAINFWLSQGAPANKLVLGVGTYGRSFQLSDSSQNWPGAPCRGEGSAGSYTGSTGYLGYNEICQNNWHTVFDYDNAAPYAYSGDQWVSFDNVLSVQYKMDFALSKGLAGAMIWSLETDDYRGQCGETYPLLKTINRKLRW", "length": 368 }, "evidence": [ { "id": "MGI:1919134", "url": "https://alliancegenome.org/gene/MGI:1919134#orthology", "database": "AGR" }, { "id": "MGI:2676649", "url": "https://alliancegenome.org/gene/MGI:2676649#orthology", "database": "AGR" }, { "id": "MGI:1330860", "url": "https://alliancegenome.org/gene/MGI:1330860#orthology", "database": "AGR" }, { "id": "MGI:1341098", "url": "https://alliancegenome.org/gene/MGI:1341098#orthology", "database": "AGR" }, { "id": "MGI:1932052", "url": "https://alliancegenome.org/gene/MGI:1932052#orthology", "database": "AGR" }, { "id": "HGNC:1932", "url": "https://alliancegenome.org/gene/HGNC:1932#orthology", "database": "AGR" }, { "id": "HGNC:17432", "url": "https://alliancegenome.org/gene/HGNC:17432#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-140106-118", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140106-118#orthology", "database": "AGR" }, { "id": "RGD:620874", "url": "https://alliancegenome.org/gene/RGD:620874#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W2M6-1", "protein_name": "chitinase", "gene_name": "Cht4", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKLVSIWALAALCLCLGQVASSEKLLNCYWGTWANYRPGDGKFTPSDIDPSLCTHISYTFFGISDAGEFKSLDTWLDMDDGLGFISQTIALKQRNPNLKILAVVGGWNEGSTKYSAMAADPAKRATFVSTSLAFIQQYSFDGLDLDWEYPGQRGGSEADRENFVTLLREIKETYDQYGLELGIAVGASEKSASISYDIPAISQHLTFINVMTYDFHMALDGYLGLNAPLPEVAESIDYWLSHGAPAEKLILGIGFYGHSYQMSDSSQNWPGAACIGPGTAGVYTRENGFLGYHEICLNNWQTVFDQENGAPYAFQGDQWIGYDNPESIQLKMQLVESRNLGGAMMWSIETDDFRGLCGESYPLLKTMNRALGREVSGGSGGGGGGGGEGSVTPAPTAAPTSSPTPAPTPGGGSGGNECAQDGFFVLESDCNKFYQCVGGVRYDFQCGAGLCFNTITLNCDWP", "length": 462 }, "evidence": [ { "id": "MGI:1919134", "url": "https://alliancegenome.org/gene/MGI:1919134#orthology", "database": "AGR" }, { "id": "MGI:2676649", "url": "https://alliancegenome.org/gene/MGI:2676649#orthology", "database": "AGR" }, { "id": "MGI:1330860", "url": "https://alliancegenome.org/gene/MGI:1330860#orthology", "database": "AGR" }, { "id": "MGI:1341098", "url": "https://alliancegenome.org/gene/MGI:1341098#orthology", "database": "AGR" }, { "id": "MGI:1932052", "url": "https://alliancegenome.org/gene/MGI:1932052#orthology", "database": "AGR" }, { "id": "HGNC:17432", "url": "https://alliancegenome.org/gene/HGNC:17432#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-140106-118", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140106-118#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W2M7-1", "protein_name": "chitinase", "gene_name": "Cht8", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MWSVSGLVKLLLGVILMAASSSAQGNSSKNVVCYQGTWSVYRPGLGKFGMEDIDPFLCTHLIYAFLGIEETGQLRVIDAYLDLEENSGRGNIKSFNALKLKNPVLKTLVAVGGWNEGSKRFSLVARDPSKREKFVDDVVRFLQRHGFDGLDLDWEYPGQRHSLDNEDRSNYITFLKELKEGLEPFGFILSAAVGSAQFSAEISYDIPAMVPYLDLINVMAYDLHGPWDQVVGINAPLYAAEKDASDSSGRQQQLNVDAVVKYWLKAGAPAEKLILGVPFYGRSFTLATAEGNQPGAPHIGKGIAGNYSREPGVLGYNELCEMMEREEWTQKWEATQQVPYAYRQRQWVGYEDPRSLALKAQYVMDNHLGGIMIWSLESDDFRGTCGQQPYPLLHEINRVLFGGNTPSGLTTESNRESPSEGFSCPADAPAGYIRDPDNCSKFYYCSGGKTHNFDCPSGLNFDLDTKSCNYSGSVKC", "length": 476 }, "evidence": [ { "id": "MGI:1919134", "url": "https://alliancegenome.org/gene/MGI:1919134#orthology", "database": "AGR" }, { "id": "MGI:2676649", "url": "https://alliancegenome.org/gene/MGI:2676649#orthology", "database": "AGR" }, { "id": "MGI:1330860", "url": "https://alliancegenome.org/gene/MGI:1330860#orthology", "database": "AGR" }, { "id": "MGI:1341098", "url": "https://alliancegenome.org/gene/MGI:1341098#orthology", "database": "AGR" }, { "id": "MGI:1932052", "url": "https://alliancegenome.org/gene/MGI:1932052#orthology", "database": "AGR" }, { "id": "HGNC:1936", "url": "https://alliancegenome.org/gene/HGNC:1936#orthology", "database": "AGR" }, { "id": "HGNC:17432", "url": "https://alliancegenome.org/gene/HGNC:17432#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-140106-118", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140106-118#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W303-1", "protein_name": "Chitinase-like protein Idgf4", "gene_name": "Idgf4", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKLYALFSLLVGSLAIGQISAAGSHHLLCYYDGNSFVREGLSKLILTDLEPALQYCTHLVYGYAGINPSSNKLVSNNEKLDLDLGSSLFRQVTGLKRKYPALKVLLSVGGDKDTVDPENNKYLTLLESSNARIPFINSAHSLVKTYGFDGLDLGWQFPKNKPKKVHGSIGKFWKGFKKIFSGDHVVDEKAEEHKEAFTALVRELKNAFRPDGYILGLSVLPNVNSSLFFDVPAIINNLDYVNLHTYDFQTPERNNEVADFPAPIYELNERNPEFNVNYQVKYWTGNRAPAAKINVGIATYGRAWKLTKDSGLTGLPPVAEADGVAPAGTQTQIPGLLSWPEVCAKLPNPANQHLKGADGPLRKVGDPTKRFGSYAYRSADDSGENGVWVGYEDPDTAAIKAEYVKREGLGGIAVVDLSFDDFRGGCTGHDKFPILRQVKSKL", "length": 442 }, "evidence": [ { "id": "MGI:1919134", "url": "https://alliancegenome.org/gene/MGI:1919134#orthology", "database": "AGR" }, { "id": "HGNC:1932", "url": "https://alliancegenome.org/gene/HGNC:1932#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-140106-118", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140106-118#orthology", "database": "AGR" }, { "id": "RGD:620874", "url": "https://alliancegenome.org/gene/RGD:620874#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W3V1-1", "protein_name": "3.2.1.14", "gene_name": "Cht11", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGNYEKLDGSSAGRITDELSRKEQRNCSLRTLVCWSALLFSLLCLCLGFIGLGLLGIQTGEVHKVGQRLVCYYASDGTHNLSLLDVPGDLCTHINIGPATLDNATIVLPDTLRQVLQNDTRSFRAAHPQVHLLLWIGGADSGRSFALMVANHAMRKLFLRSLREILRTYPSLDGIDLDWEFPSAYDRERMHLSQLLYEIRTEWRREKRTNDILSLAVAAPEGIAFYAYDIREINLYADYVNLMSYDFHFYREDTPFTGLNAPLYARSQERSLMATFNINYTVQWWLKSGLEPQRLVVGLPTYGHSFTLVNPLNHRIGAPASGYGKCGQLGFTTLTETCECVTKFFKPNLSYDAESCSPYLSALQEWISYENQTSIACKANYVKSLNLGGVMVFSLNTDDLKNSCSIMPNLKYSEKPVFPLTQAIKDILRESL", "length": 432 }, "evidence": [ { "id": "MGI:1919134", "url": "https://alliancegenome.org/gene/MGI:1919134#orthology", "database": "AGR" }, { "id": "HGNC:1936", "url": "https://alliancegenome.org/gene/HGNC:1936#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-140106-118", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140106-118#orthology", "database": "AGR" }, { "id": "RGD:620874", "url": "https://alliancegenome.org/gene/RGD:620874#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W5U2-1", "protein_name": "Probable chitinase 10", "gene_name": "Cht10", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MHPYVPSVLVVVVLAISVKAHIRVDKLQIHSESNYKPAFIRSAVESIPLDIDAILLLRNSTKPEFGDAFLPLRSAVESIPKLYQSNTSRFRKNPDVRSFVRDSVESLPNDEDGLEHIEIFTKYYNSVSDVAGVDLKSKKLTHVNLDPGTISDKYAAFIARGNSEDYYPKSYRAGSPHQELLKMMNIEHTDKLDRYSDLQHQQSYGALGLANRNDLKMTKKVLCYMSNWAFYRSGEAHFVPEQIDPNLCSAIIYSFASLDPDHLTIREFDSWVDLDNQYYRRVTSLGVPVLIALGGWTDSSGSKYSRLVSDNLKRRVFISSVSSFLLRHGFSGLHLDWNYPKCWQSDCSRGPVTDRPNLTKLLRELRTEFQSVDPKFQLGVAISGYKEIIKEAYDFPALSDIVDYMTVMTYDYHGAWEQKTGHVSPLYGLSSDTYPQYNTNYTMQLLLKMGARREKLVLSIPFYGQSFTLATAHQILAGPGVAASGPGDAGELTKQPGMLAYYEICQRLTKFNWISDRNLNVIFGPFAMLNDQWVGYEDPTSAQAKARYAANNNFAGVAAWTIDLDDFRNLCCNESYPLLRAINRALGRLDSEPPTQPNCKRPTLLATPVPPQMTTISSDGSGGLGQNHDHTTSLPSGQISSSPVSTTITSTFPWWSSTTKRPREPTKTTAQPTHTTILIPAGINPVVQPSNCKSGEFFADSNNCNAYYHCFFAGELQQQFCPSGLHWNNEAKGCDWPSSAQCSLKLDQHLSTSYPNPIQTSKKPETTLKPNKKPSEISTHHQVNSTSSRPQYMRPTILECTEGDYYPHRNCRKYYICVNKALVPSECGGDLHWDGIKKLCDWPENVQCVTSKKYLKIIKSSSANEEDPCKGEKRVPYPGNCSKYLFCLWNRLQASDCPPGLHYNERIGNCDWPAAAKCNPKGSESSEEAELNAMPKPPTPQTPSSHLRPTYPTEKPVPKPRDSHYKVICYFTNWAWYRKGIGRFTPDDINTELCTHVIYGFAVLDYSELVLRTHDSWADVENNFYTRVTSLKSKGIKVSLALGGWNDSQGDKYSRLVRSPMARSRFVRHALEFIEKYGFEGLDLDWEYPVCWQTECNKGSTEEKDGFTAWVQELSEAFRPRGLMLSTAVSPSRKIIDAGYDIPQLSRYFDWIAVMTYDFHGHWDKKTGHVAPLYHHPDDDFEYFNVNYSINYWMEKGAPSQKLVMGIPLYGQSFTLENTNSSGLNAKAPAPGEAGEFTRAAGFLAYYEICERVNRQGWQVVHDEFGRMGPYAYKGTQWVSYDSPDMVRKKSLLVRSLKLGGGMVWALDLDDFKNRCGNGVHPLLTEIHNVLKDPPSLMEIPGPIETTPTEYPGMEEEIHESNGEGPEVQPIEAVMQTCENEGEEHEGILDPNHVLEEENIEATEMATEFKIICYFTNWAWYRQGGGKFLPEDIDSDLCTHIIYGFAVLSRDNLTIQPHDSWADLDNKFYERIVAYRKKGAKVTVAIGGWNDSAGDKYSRLVRNPEARSRFIRNVLDFIEEYNFDGLDLDWEYPVCWQVDCKKGTAEEKIGFSALVRELFYAFQPRGLILSAAVSPNKKVIDAGYEVAELSHYFSWISVMAYDYHGQWDKKTGHVAPMYSHPEGTANFNANFSMNYWISMGADRRKLVMGIPLYGQSFSLAETTKHQLNAPTYGGGEAGEATRARGFLAYYEICLKIRHHRWNVVRDTKGRIGPFAYHGDQWVSFDDVPMIRHKSEYIKAMGLGGAMIWALDLDDFKNVCECESYPLLKAINRVLRGFGGPQPKCLLENPKSTMKPNIKPPFRPTINAPSGPNLDSPTQNVSLNVLSIKCHSKNYLAHEWDCTKYYICEHGTYVERSCPLGLQWNKTYCDWPTNVQSSLGSNQRTQEPAVHRPNPTSVITEPPIINNSYKVVCYFTSWAWYRSSQGKFVPEDIDANLCTHLIYGFAVLDSKSLTIKTHDSWTDIDNRFYERVVEYKQRGLRVMLAIGGWNDSLGSKYARLVLNSQSRRRFVASVISFLEQHGFEGLDLAWEFPVCWQVNCNRGNPTEKDGFVALVKELSEAFKENGLILSAAVSPSKMVIDAGYNVFELSPYFDWVAVMTYDFHGHWDMRTGQIAPLFHRGGDENLYLNGNFSIHYWLERGIPNDKLVMGMPMYGQTFTLADQNRRSLNDKTVGPGKAGTFTRADGFLAYYEICEKVVNDDWKVVRDEEGIFGSYAYSGNQWISYDDVTTIRRKSQFIKSLQLGGGMIWALDLDDFRGLCGCGKHPLLRTLSQELLGIPGQKAKDCI", "length": 2286 }, "evidence": [ { "id": "MGI:106661", "url": "https://alliancegenome.org/gene/MGI:106661#orthology", "database": "AGR" }, { "id": "MGI:1919134", "url": "https://alliancegenome.org/gene/MGI:1919134#orthology", "database": "AGR" }, { "id": "HGNC:1932", "url": "https://alliancegenome.org/gene/HGNC:1932#orthology", "database": "AGR" }, { "id": "HGNC:1936", "url": "https://alliancegenome.org/gene/HGNC:1936#orthology", "database": "AGR" }, { "id": "HGNC:1933", "url": "https://alliancegenome.org/gene/HGNC:1933#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-140106-118", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140106-118#orthology", "database": "AGR" }, { "id": "RGD:620874", "url": "https://alliancegenome.org/gene/RGD:620874#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9WTV1-1", "protein_name": "Chitinase-3-like protein 1", "gene_name": "Chi3l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTLQLPGFAVLMLLQSCSAYKLVCYYTNWSQYREGNGSCFPDALDHSLCTHIIYSFANISNNKLSTSEWNDVTLYGMLNTLKTRNPRLKTLLSVGGWSFGSERFSRIVSNAKSRKTFVQSVAPFLRTYGFDGLDLAWLYPGPKDKQHFTTLIKELKAEFTKEVQPGTEKLLLSAAVSAGKVTLDSGYDVAQIAQHLDFINLMTYDFHGTWRHTTGHHSPLFRGQQDTGPDRFSNVDYGVGYMLRLGAPTNKLVMGIPTFGKSFTLASSENQVGAPITGSGLPGRYTKEKGTLAYYEICDFLRGAEVHRILGQQVPFATKGNQWVGYDDPESVKNKVKYLKNKQLAGAMVWAVDLDDFRGSFCGHNVHFPLTNAIKEALAVA", "length": 381 }, "evidence": [ { "id": "MGI:1340899", "url": "https://alliancegenome.org/gene/MGI:1340899#orthology", "database": "AGR" }, { "id": "HGNC:1932", "url": "https://alliancegenome.org/gene/HGNC:1932#orthology", "database": "AGR" }, { "id": "FB:FBgn0035398", "url": "https://alliancegenome.org/gene/FB:FBgn0035398#orthology", "database": "AGR" }, { "id": "RGD:620874", "url": "https://alliancegenome.org/gene/RGD:620874#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q9VZV2", "url": "https://www.uniprot.org/uniprotkb/Q9VZV2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "Q9VZV2", "url": "https://www.uniprot.org/uniprotkb/Q9VZV2" } ], "pmid": "" }, { "name": "wound healing", "id": "GO:0042060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042060", "evidence": [ { "database": "UniProtKB", "id": "Q9VZV2", "url": "https://www.uniprot.org/uniprotkb/Q9VZV2" } ], "pmid": "" }, { "name": "chitin catabolic process", "id": "GO:0006032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006032", "evidence": [ { "database": "UniProtKB", "id": "Q9VZV2", "url": "https://www.uniprot.org/uniprotkb/Q9VZV2" } ], "pmid": "" }, { "name": "regulation of tube architecture, open tracheal system", "id": "GO:0035152", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035152", "evidence": [ { "database": "UniProtKB", "id": "Q9VZV2", "url": "https://www.uniprot.org/uniprotkb/Q9VZV2" } ], "pmid": "" }, { "name": "ecdysis, chitin-based cuticle", "id": "GO:0018990", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018990", "evidence": [ { "database": "UniProtKB", "id": "Q9VZV2", "url": "https://www.uniprot.org/uniprotkb/Q9VZV2" } ], "pmid": "" }, { "name": "chitin-based cuticle development", "id": "GO:0040003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040003", "evidence": [ { "database": "UniProtKB", "id": "Q9VZV2", "url": "https://www.uniprot.org/uniprotkb/Q9VZV2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "chitinase activity", "id": "GO:0004568", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004568", "evidence": [ { "database": "UniProtKB", "id": "Q9VZV2", "url": "https://www.uniprot.org/uniprotkb/Q9VZV2" } ], "pmid": "" }, { "name": "endochitinase activity", "id": "GO:0008843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008843", "evidence": [ { "database": "UniProtKB", "id": "Q9VZV2", "url": "https://www.uniprot.org/uniprotkb/Q9VZV2" } ], "pmid": "" }, { "name": "chitin binding", "id": "GO:0008061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008061", "evidence": [ { "database": "UniProtKB", "id": "Q9VZV2", "url": "https://www.uniprot.org/uniprotkb/Q9VZV2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 504, "end_pos": 506, "annotation": "n_glycosylation_sequon" }, { "start_pos": 807, "end_pos": 809, "annotation": "n_glycosylation_sequon" }, { "start_pos": 846, "end_pos": 848, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-DME-6786421", "name": "CHIA hydrolyses chitin", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region", "input_participant_list": [ "R-ALL-6786438" ], "output_participant_list": [ "R-ALL-6786426", "R-ALL-6786428" ], "enzyme_list": [ "Q9W5U2-1", "M9NDS9-1", "Q9W2M5-1", "Q8MLW8-1", "Q9W2M7-1", "Q9W092-1", "Q9W3V1-1", "Q9VFR3-1", "Q9VZV2-1", "Q9W2M6-1" ], "evidence": [ { "id": "R-DME-6786421", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6786421" } ] }, { "id": "R-DME-6786652", "name": "CHIT1 hydrolyses CHIT to 3xADGP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region", "input_participant_list": [ "R-ALL-6786654" ], "output_participant_list": [ "R-ALL-6786660" ], "enzyme_list": [ "Q9W5U2-1", "M9NDS9-1", "Q9W2M5-1", "Q8MLW8-1", "Q9W2M7-1", "Q9W092-1", "Q9W3V1-1", "Q9VFR3-1", "Q9VZV2-1", "Q9W2M6-1" ], "evidence": [ { "id": "R-DME-6786652", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6786652" } ] }, { "id": "R-DME-6798745", "name": "Exocytosis of tertiary granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, tertiary granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q8INK6-1", "A1Z9D5-1", "A1ZBX6-1", "C0HK98-1", "C0HK99-1", "P29349-4", "Q9VV96-1", "Q9W5U2-1", "M9NDS9-1", "Q9W2M5-1", "P29615-1", "Q9V4X2-1", "Q9VYX7-1", "Q8MLW8-1", "Q9W2M7-1", "A1ZBX7-1", "Q9VBF5-1", "Q9VLR2-1", "Q9W122-1", "Q9W4C2-1", "Q7KRU8-1", "P07764-1", "Q8MPP3-1", "Q9W092-1", "B7Z0E0-1", "Q86PD7-1", "Q9W3V1-1", "A1ZAB8-1", "Q8IQM9-1", "Q9VJ39-1", "P37159-1", "P37160-1", "P37161-1", "P83972-1", "Q08694-1", "Q70PY2-1", "Q9VSA5-1", "Q9VUY9-1", "Q9VFR3-1", "Q9VGN8-1", "Q9VHE4-1", "Q9VYH1-1", "Q9VZV2-1", "Q9W2M6-1" ], "evidence": [ { "id": "R-DME-6798745", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6798745" } ] }, { "id": "R-DME-6798749", "name": "Exocytosis of specific granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, specific granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q8INK6-1", "A1Z9D5-1", "A1ZBX6-1", "Q7KUC2-1", "C0HK98-1", "C0HK99-1", "P29349-4", "Q9VV96-1", "Q9W5U2-1", "M9NDS9-1", "Q9W2M5-1", "P29615-1", "Q9V4X2-1", "Q9V9J3-1", "Q9VYX7-1", "Q8MLW8-1", "Q9W2M7-1", "A1ZBX7-1", "O76895-1", "Q9W122-1", "Q9W4C2-1", "Q8MPP3-1", "Q9W092-1", "Q86PD7-1", "Q9W3V1-1", "A1ZAB8-1", "Q8IQM9-1", "P37159-1", "P37160-1", "P37161-1", "P83972-1", "Q08694-1", "Q70PY2-1", "Q9VSA5-1", "Q9VFR3-1", "Q9VGN8-1", "Q9VHE4-1", "Q9VZV2-1", "Q9W2M6-1" ], "evidence": [ { "id": "R-DME-6798749", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6798749" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-6786426", "participant_name": "GlcNAc-beta1,4-GlcNAc-beta1,4-GlcNAc [extracellular region]", "crossref": [ { "id": "86362", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-6786428", "participant_name": "GlcNAc-beta1,4-GlcNAc [extracellular region]", "crossref": [ { "id": "86361", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-6786438", "participant_name": "chitin [extracellular region]", "crossref": [ { "id": "17029", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-6786654", "participant_name": "CHIT [extracellular region]", "crossref": [ { "id": "84373", "database": "ChEBI", "url": "" }, { "id": "ZINC000056870823", "database": "ZINC", "url": "" }, { "id": "ZINC000070665912", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-6786660", "participant_name": "ADGP [extracellular region]", "crossref": [ { "id": "47977", "database": "ChEBI", "url": "" }, { "id": "G80384UV", "database": "GlyTouCan", "url": "" }, { "id": "ZINC000003860468", "database": "ZINC", "url": "" }, { "id": "HMDB0001514", "database": "HMDB Metabolite", "url": "" }, { "id": "ZINC000003860469", "database": "ZINC", "url": "" }, { "id": "C00329", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A1Z9D5", "gene_name": "Dmel\\CG30062", "activity": [ { "ec_number": "3.2.1.17", "activity": "Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.", "evidence": [ { "id": "A1Z9D5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1Z9D5" } ] }, { "ec_number": "3.2.1.17", "activity": "", "evidence": [ { "id": "A1Z9D5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1Z9D5" } ] } ] }, { "uniprot_ac": "A1ZAB8", "gene_name": "Dmel\\CG7798", "activity": [ { "ec_number": "3.2.1.17", "activity": "Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.", "evidence": [ { "id": "A1ZAB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1ZAB8" } ] }, { "ec_number": "3.2.1.17", "activity": "", "evidence": [ { "id": "A1ZAB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1ZAB8" } ] } ] }, { "uniprot_ac": "A1ZBX6", "gene_name": "Dmel\\CG16799", "activity": [ { "ec_number": "3.2.1.17", "activity": "Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.", "evidence": [ { "id": "A1ZBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1ZBX6" } ] }, { "ec_number": "3.2.1.17", "activity": "", "evidence": [ { "id": "A1ZBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1ZBX6" } ] } ] }, { "uniprot_ac": "A1ZBX7", "gene_name": "Dmel\\CG11159", "activity": [ { "ec_number": "3.2.1.17", "activity": "Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.", "evidence": [ { "id": "A1ZBX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1ZBX7" } ] }, { "ec_number": "3.2.1.17", "activity": "", "evidence": [ { "id": "A1ZBX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1ZBX7" } ] } ] }, { "uniprot_ac": "B7Z0E0", "gene_name": "Idh", "activity": [ { "ec_number": "1.1.1.42", "activity": "D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH.", "evidence": [ { "id": "B7Z0E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B7Z0E0" } ] }, { "ec_number": "1.1.1.42", "activity": "", "evidence": [ { "id": "B7Z0E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B7Z0E0" } ] } ] }, { "uniprot_ac": "C0HK98", "gene_name": "PGRP-SC1a", "activity": [ { "ec_number": "3.5.1.28", "activity": "Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides.", "evidence": [ { "id": "C0HK98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/C0HK98" } ] }, { "ec_number": "3.5.1.28", "activity": "", "evidence": [ { "id": "C0HK98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/C0HK98" } ] } ] }, { "uniprot_ac": "C0HK99", "gene_name": "PGRP-SC1b", "activity": [ { "ec_number": "3.5.1.28", "activity": "Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides.", "evidence": [ { "id": "C0HK99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/C0HK99" } ] }, { "ec_number": "3.5.1.28", "activity": "", "evidence": [ { "id": "C0HK99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/C0HK99" } ] } ] }, { "uniprot_ac": "M9NDS9", "gene_name": "Cht6", "activity": [ { "ec_number": "3.2.1.14", "activity": "Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins.", "evidence": [ { "id": "M9NDS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9NDS9" } ] }, { "ec_number": "3.2.1.14", "activity": "", "evidence": [ { "id": "M9NDS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9NDS9" } ] } ] }, { "uniprot_ac": "O76895", "gene_name": "Arg", "activity": [ { "ec_number": "3.5.3.1", "activity": "L-arginine + H2O = urea + L-ornithine.", "evidence": [ { "id": "O76895", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O76895" } ] }, { "ec_number": "3.5.3.1", "activity": "", "evidence": [ { "id": "O76895", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O76895" } ] } ] }, { "uniprot_ac": "P07764", "gene_name": "Aldo", "activity": [ { "ec_number": "4.1.2.13", "activity": "beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate.", "evidence": [ { "id": "P07764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P07764" } ] }, { "ec_number": "4.1.2.13", "activity": "", "evidence": [ { "id": "P07764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P07764" } ] } ] }, { "uniprot_ac": "P29349", "gene_name": "csw", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P29349", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P29349" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P29349", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P29349" } ] } ] }, { "uniprot_ac": "P29615", "gene_name": "LysP", "activity": [ { "ec_number": "3.2.1.17", "activity": "Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.", "evidence": [ { "id": "P29615", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P29615" } ] }, { "ec_number": "3.2.1.17", "activity": "", "evidence": [ { "id": "P29615", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P29615" } ] } ] }, { "uniprot_ac": "P37159", "gene_name": "LysE", "activity": [ { "ec_number": "3.2.1.17", "activity": "Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.", "evidence": [ { "id": "P37159", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P37159" } ] }, { "ec_number": "3.2.1.17", "activity": "", "evidence": [ { "id": "P37159", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P37159" } ] } ] }, { "uniprot_ac": "P37160", "gene_name": "LysS", "activity": [ { "ec_number": "3.2.1.17", "activity": "Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.", "evidence": [ { "id": "P37160", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P37160" } ] }, { "ec_number": "3.2.1.17", "activity": "", "evidence": [ { "id": "P37160", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P37160" } ] } ] }, { "uniprot_ac": "P37161", "gene_name": "LysX", "activity": [ { "ec_number": "3.2.1.17", "activity": "Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.", "evidence": [ { "id": "P37161", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P37161" } ] }, { "ec_number": "3.2.1.17", "activity": "", "evidence": [ { "id": "P37161", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P37161" } ] } ] }, { "uniprot_ac": "P83972", "gene_name": "LysD", "activity": [ { "ec_number": "3.2.1.17", "activity": "Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.", "evidence": [ { "id": "P83972", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P83972" } ] }, { "ec_number": "3.2.1.17", "activity": "", "evidence": [ { "id": "P83972", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P83972" } ] } ] }, { "uniprot_ac": "Q08694", "gene_name": "LysB", "activity": [ { "ec_number": "3.2.1.17", "activity": "Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.", "evidence": [ { "id": "Q08694", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08694" } ] }, { "ec_number": "3.2.1.17", "activity": "", "evidence": [ { "id": "Q08694", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q08694" } ] } ] }, { "uniprot_ac": "Q70PY2", "gene_name": "PGRP-SB1", "activity": [ { "ec_number": "3.5.1.28", "activity": "Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides.", "evidence": [ { "id": "Q70PY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q70PY2" } ] }, { "ec_number": "3.5.1.28", "activity": "", "evidence": [ { "id": "Q70PY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q70PY2" } ] } ] }, { "uniprot_ac": "Q7KRU8", "gene_name": "Fer1HCH", "activity": [ { "ec_number": "1.16.3.1", "activity": "4 Fe(2+) + O2 + 4 H(+) = 4 Fe(3+) + 2 H2O.", "evidence": [ { "id": "Q7KRU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7KRU8" } ] }, { "ec_number": "1.16.3.1", "activity": "", "evidence": [ { "id": "Q7KRU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7KRU8" } ] } ] }, { "uniprot_ac": "Q7KUC2", "gene_name": "Pdxk", "activity": [ { "ec_number": "2.7.1.35", "activity": "pyridoxine + ATP = pyridoxine 5'-phosphate + ADP + H(+).", "evidence": [ { "id": "Q7KUC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7KUC2" } ] }, { "ec_number": "2.7.1.35", "activity": "", "evidence": [ { "id": "Q7KUC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7KUC2" } ] } ] }, { "uniprot_ac": "Q86PD7", "gene_name": "isoQC", "activity": [ { "ec_number": "2.3.2.5", "activity": "N-terminal L-glutaminyl-[peptide] = N-terminal 5-oxo-L-prolyl-[peptide] + NH4(+).", "evidence": [ { "id": "Q86PD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q86PD7" } ] }, { "ec_number": "2.3.2.5", "activity": "", "evidence": [ { "id": "Q86PD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q86PD7" } ] } ] }, { "uniprot_ac": "Q8INK6", "gene_name": "PGRP-LB", "activity": [ { "ec_number": "3.5.1.28", "activity": "Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides.", "evidence": [ { "id": "Q8INK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8INK6" } ] }, { "ec_number": "3.5.1.28", "activity": "", "evidence": [ { "id": "Q8INK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8INK6" } ] } ] }, { "uniprot_ac": "Q8IQM9", "gene_name": "l(3)72Dp", "activity": [ { "ec_number": "3.4.19.9", "activity": "(6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) + (n-1) H2O = (6S)-5,6,7,8-tetrahydrofolate + (n-1) L-glutamate.", "evidence": [ { "id": "Q8IQM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8IQM9" } ] }, { "ec_number": "3.4.19.9", "activity": "", "evidence": [ { "id": "Q8IQM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8IQM9" } ] } ] }, { "uniprot_ac": "Q8MLW8", "gene_name": "Cht12", "activity": [ { "ec_number": "3.2.1.14", "activity": "Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins.", "evidence": [ { "id": "Q8MLW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8MLW8" } ] } ] }, { "uniprot_ac": "Q8MPP3", "gene_name": "Mmp2", "activity": [ { "ec_number": "3.4.24.-", "activity": "", "evidence": [ { "id": "Q8MPP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8MPP3" } ] } ] }, { "uniprot_ac": "Q9V4X2", "gene_name": "PGRP-SC2", "activity": [ { "ec_number": "3.5.1.28", "activity": "Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides.", "evidence": [ { "id": "Q9V4X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9V4X2" } ] }, { "ec_number": "3.5.1.28", "activity": "", "evidence": [ { "id": "Q9V4X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9V4X2" } ] } ] }, { "uniprot_ac": "Q9V9J3", "gene_name": "Src42A", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q9V9J3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9V9J3" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "Q9V9J3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9V9J3" } ] } ] }, { "uniprot_ac": "Q9VBF5", "gene_name": "Aldol", "activity": [ { "ec_number": "4.1.2.13", "activity": "beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate.", "evidence": [ { "id": "Q9VBF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VBF5" } ] }, { "ec_number": "4.1.2.13", "activity": "", "evidence": [ { "id": "Q9VBF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VBF5" } ] } ] }, { "uniprot_ac": "Q9VFR3", "gene_name": "Cht5", "activity": [ { "ec_number": "3.2.1.14", "activity": "Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins.", "evidence": [ { "id": "Q9VFR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VFR3" } ] }, { "ec_number": "3.2.1.14", "activity": "", "evidence": [ { "id": "Q9VFR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VFR3" } ] } ] }, { "uniprot_ac": "Q9VGN8", "gene_name": "Dmel\\CG5276", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "Q9VGN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VGN8" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "Q9VGN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VGN8" } ] } ] }, { "uniprot_ac": "Q9VHE4", "gene_name": "Dmel\\CG8132", "activity": [ { "ec_number": "3.5.1.3", "activity": "2-oxosuccinamate + H2O = oxaloacetate + NH4(+).", "evidence": [ { "id": "Q9VHE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VHE4" } ] }, { "ec_number": "3.5.1.3", "activity": "", "evidence": [ { "id": "Q9VHE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VHE4" } ] } ] }, { "uniprot_ac": "Q9VJ39", "gene_name": "pepCG10602", "activity": [ { "ec_number": "3.3.2.6", "activity": "leukotriene A4 + H2O = leukotriene B4.", "evidence": [ { "id": "Q9VJ39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJ39" } ] }, { "ec_number": "3.3.2.6", "activity": "", "evidence": [ { "id": "Q9VJ39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJ39" } ] } ] }, { "uniprot_ac": "Q9VLR2", "gene_name": "Dmel\\CG8353", "activity": [ { "ec_number": "3.5.4.5", "activity": "cytidine + H2O + H(+) = uridine + NH4(+).", "evidence": [ { "id": "Q9VLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VLR2" } ] }, { "ec_number": "3.5.4.5", "activity": "", "evidence": [ { "id": "Q9VLR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VLR2" } ] } ] }, { "uniprot_ac": "Q9VSA5", "gene_name": "Dmel\\CG8492", "activity": [ { "ec_number": "3.2.1.17", "activity": "Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.", "evidence": [ { "id": "Q9VSA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSA5" } ] }, { "ec_number": "3.2.1.17", "activity": "", "evidence": [ { "id": "Q9VSA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSA5" } ] } ] }, { "uniprot_ac": "Q9VUY9", "gene_name": "Pgm1", "activity": [ { "ec_number": "5.4.2.2", "activity": "alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate.", "evidence": [ { "id": "Q9VUY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUY9" } ] }, { "ec_number": "5.4.2.2", "activity": "", "evidence": [ { "id": "Q9VUY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUY9" } ] } ] }, { "uniprot_ac": "Q9VV96", "gene_name": "PGRP-SB2", "activity": [ { "ec_number": "3.5.1.28", "activity": "Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides.", "evidence": [ { "id": "Q9VV96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VV96" } ] }, { "ec_number": "3.5.1.28", "activity": "", "evidence": [ { "id": "Q9VV96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VV96" } ] } ] }, { "uniprot_ac": "Q9VYH1", "gene_name": "Fer3HCH", "activity": [ { "ec_number": "1.16.3.1", "activity": "4 Fe(2+) + O2 + 4 H(+) = 4 Fe(3+) + 2 H2O.", "evidence": [ { "id": "Q9VYH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VYH1" } ] }, { "ec_number": "1.16.3.1", "activity": "", "evidence": [ { "id": "Q9VYH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VYH1" } ] } ] }, { "uniprot_ac": "Q9VYX7", "gene_name": "PGRP-SA", "activity": [ { "ec_number": "3.4.17.13", "activity": "N-acetyl-D-glucosaminyl-N-acetylmuramoyl-L-alanyl-meso-2,6-diaminoheptanedioyl-D-alanine + H2O = N-acetyl-D-glucosaminyl-N-acetylmuramoyl-L-alanyl-meso-2,6-diaminoheptanedioate + D-alanine.", "evidence": [ { "id": "Q9VYX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VYX7" } ] }, { "ec_number": "3.4.17.13", "activity": "", "evidence": [ { "id": "Q9VYX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VYX7" } ] } ] }, { "uniprot_ac": "Q9VZV2", "gene_name": "Cht7", "activity": [ { "ec_number": "3.2.1.-", "activity": "", "evidence": [ { "id": "Q9VZV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZV2" } ] }, { "ec_number": "3.2.1.14", "activity": "Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins.", "evidence": [ { "id": "Q9VZV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VZV2" } ] } ] }, { "uniprot_ac": "Q9W092", "gene_name": "Cht2", "activity": [ { "ec_number": "3.2.1.14", "activity": "Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins.", "evidence": [ { "id": "Q9W092", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W092" } ] }, { "ec_number": "3.2.1.14", "activity": "", "evidence": [ { "id": "Q9W092", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W092" } ] } ] }, { "uniprot_ac": "Q9W122", "gene_name": "Mmp1", "activity": [ { "ec_number": "3.4.24.-", "activity": "", "evidence": [ { "id": "Q9W122", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W122" } ] } ] }, { "uniprot_ac": "Q9W2M5", "gene_name": "Cht9", "activity": [ { "ec_number": "3.2.1.-", "activity": "", "evidence": [ { "id": "Q9W2M5", "database": "UniProtKB", 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OX=7227 GN=Dmel\\CG9970 PE=4 SV=2 CANONICAL=Q9VZX0-1" }, "isoforms": [ { "isoform_ac": "Q9VZX0-1", "url": "https://www.uniprot.org/uniprotkb/Q9VZX0/entry#Q9VZX0-1", "sequence": { "sequence": "MEPKHGVSTTSFSSTKTLVREGESIPQDNNKSISSTIEEDLLQQNKSEKEKTKGTSTDKSTTTDGDLPTVKMDKILQQQRAELLWKTFTDEEYSDWKTFKDSNYKVPLLSVFSYVKSKPFIAEIPNLPPKISGPQLMTNILKSNYGALALVQIGENKFKCIPCLLRCFSVWFGIRDWRITRFKFKEREVPSGGFKVVYEWMRTNKLPEFDELVPALQVACHLKVTLLEKEIWQILSDESVREKVAFLVYLGARRMPALGALCEAMLFRLRKYFLALVGSPHFVRLKVDVLEMLLRQDSIGVNSEMEVFFAVIRWLGHSRGRKRREHFQRLMKCVRFHHMPMTFLFSLRESFNHPEKFDLFSKEPGMLAFNTDPEMMELLEHAIYFISVRTQCDDINEFLSTCESHHIEVVLPRWWVYHVNCPFHLRTIDFPYQHRFTATDFGDYIDSIQKVWSGKGPPDDGKDLVIDLALDPLRGGQVDGKAKE", "length": 484, "header": "tr|Q9VZX0-1|Q9VZX0_DROME Isoform 1 of BACK domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG9970 PE=4 SV=2 CANONICAL=Q9VZX0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan 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"url": "https://disease-ontology.org/term/DOID:8866", "name": "actinic (Solar) Keratosis", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "8866", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8866" } ] }, { "disease_id": "DOID:8923", "recommended_name": { "id": "DOID:8923", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8923", "name": "skin melanoma", "description": "A skin cancer that has_material_basis_in melanocytes." }, "synonyms": [ { "id": "DOID:8923", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8923", "name": "cutaneous melanoma", "description": "" }, { "id": "DOID:8923", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8923", "name": "malignant ear melanoma", "description": "" }, { "id": "DOID:8923", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8923", "name": "malignant lip melanoma", "description": "" }, { "id": "DOID:8923", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8923", "name": "malignant lower limb melanoma", "description": "" }, { "id": "DOID:8923", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8923", "name": "malignant melanoma of skin of lower limb", "description": "" }, { "id": "DOID:8923", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8923", "name": "malignant melanoma of skin of trunk except scrotum", "description": "" }, { "id": "DOID:8923", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8923", "name": "malignant melanoma of skin of upper limb", "description": "" }, { "id": "DOID:8923", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8923", "name": "malignant neck melanoma", "description": "" }, { "id": "DOID:8923", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8923", "name": "malignant scalp melanoma", "description": "" }, { "id": "DOID:8923", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8923", "name": "malignant trunk melanoma", "description": "" }, { "id": "DOID:8923", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8923", "name": "malignant upper limb melanoma", "description": "" }, { "id": "DOID:8923", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8923", "name": "malignant melanoma of ear and/or external auricular canal", "description": "" }, { "id": "DOID:8923", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8923", "name": "Cutaneous Malignant Melanoma", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "8923", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8923" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W024", "url": "https://www.uniprot.org/uniprotkb/Q9W024" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG13801", "url": "https://www.uniprot.org/uniprotkb/Q9W024", "locus": { "chromosome": "3L", "start_pos": 2362686, "end_pos": 2360557, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0035332", "url": "https://www.ensemblgenomes.org/id/FBgn0035332" } ] } } ], "crossref": [ { "id": "FB:FBgn0035332", "url": "https://alliancegenome.org/gene/FB:FBgn0035332", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0035332", "url": "https://bgee.org/?page=gene&gene_id=FBgn0035332", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01116", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01116", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0035332", "url": "https://flybase.org/reports/FBgn0035332", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "38299", "url": "https://www.ncbi.nlm.nih.gov/gene/38299", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051475", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051475", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG13801", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG13801", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KGHAWLL", "url": "https://omabrowser.org/oma/group/KGHAWLL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W024", "url": "https://www.orthodb.org/?gene=Q9W024", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43568", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43568", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43568:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43568:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03600", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03600", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_647714", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647714", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W024", "url": "https://www.uniprot.org/uniprotkb/Q9W024", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W024-1", "url": "https://www.uniprot.org/uniprotkb/Q9W024-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNPIIKKYRLRLRRTERDSTIGYVFRIIRIVILLSLWTGSTIILFLHKPEELATSMVTVMPNKTAFRNVKMKQDSVEIRLNGAINAYLTNHRVRTSNFSAVGVRLEWRDRGMNRSLWRTGMWMVYMYKDKKKYLQVNRVFQFSISGWQQERSLIQRTLPTDRSLENSVYDWAFAQTVISFESMSKDPVGLLMTVNSTPLEHGLGILYAALLLIGLYAIIIWEFSDRILSTLLITAMSLALLTVLGSRPTLETIVSWVDWETMMLLLGNMIITSRMADTGFFDYLAVVAYRISKGHAWLLIGLLGFFVGLTSTVVDNATVVLLFCPPVIRLCEVMDLRTTLVLIIVAIYANIGGSITPVSGPPNTIIATNKMVESAGINFVRFSLLMLPTALICLASTFGLIYWTMGKKIYILDEDQVNLAEKRRENTRTSFDIQLRVAELRRQPRSKVIPPAESYFITLATLEASNFVRKKVLLVESLLALSFAAFCFILQSVPWAIPGASLGWISILSAFLLLILIDQKDIIKVMASVEWGIMLLLASLFIFTMVVDELGLIHWLGSQVVSVILRVDESYQTMVGMLLILWLSALLSAFIHNAAVAPIMVKLCTDMVVYDQVQMPLLPLIWATSMGTSYGANGTLLGSLANEFAAVVGKAHGYKITFRSFFVVGFLIMLFTVVICSIFLIIAHSIFDWH", "length": 690, "header": "tr|Q9W024-1|Q9W024_DROME Isoform 1 of Citrate transporter-like domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG13801 PE=4 SV=1 CANONICAL=Q9W024-1" }, "isoforms": [ { "isoform_ac": "Q9W024-1", "url": "https://www.uniprot.org/uniprotkb/Q9W024/entry#Q9W024-1", "sequence": { "sequence": "MNPIIKKYRLRLRRTERDSTIGYVFRIIRIVILLSLWTGSTIILFLHKPEELATSMVTVMPNKTAFRNVKMKQDSVEIRLNGAINAYLTNHRVRTSNFSAVGVRLEWRDRGMNRSLWRTGMWMVYMYKDKKKYLQVNRVFQFSISGWQQERSLIQRTLPTDRSLENSVYDWAFAQTVISFESMSKDPVGLLMTVNSTPLEHGLGILYAALLLIGLYAIIIWEFSDRILSTLLITAMSLALLTVLGSRPTLETIVSWVDWETMMLLLGNMIITSRMADTGFFDYLAVVAYRISKGHAWLLIGLLGFFVGLTSTVVDNATVVLLFCPPVIRLCEVMDLRTTLVLIIVAIYANIGGSITPVSGPPNTIIATNKMVESAGINFVRFSLLMLPTALICLASTFGLIYWTMGKKIYILDEDQVNLAEKRRENTRTSFDIQLRVAELRRQPRSKVIPPAESYFITLATLEASNFVRKKVLLVESLLALSFAAFCFILQSVPWAIPGASLGWISILSAFLLLILIDQKDIIKVMASVEWGIMLLLASLFIFTMVVDELGLIHWLGSQVVSVILRVDESYQTMVGMLLILWLSALLSAFIHNAAVAPIMVKLCTDMVVYDQVQMPLLPLIWATSMGTSYGANGTLLGSLANEFAAVVGKAHGYKITFRSFFVVGFLIMLFTVVICSIFLIIAHSIFDWH", "length": 690, "header": "tr|Q9W024-1|Q9W024_DROME Isoform 1 of Citrate transporter-like domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG13801 PE=4 SV=1 CANONICAL=Q9W024-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W024", "url": "https://www.uniprot.org/uniprotkb/Q9W024" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W024", "url": "https://www.uniprot.org/uniprotkb/Q9W024" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W024", "url": "https://www.uniprot.org/uniprotkb/Q9W024" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W024", "url": "https://www.uniprot.org/uniprotkb/Q9W024" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W024", "url": "https://www.uniprot.org/uniprotkb/Q9W024" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W024", "url": "https://www.uniprot.org/uniprotkb/Q9W024" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W024", "url": "https://www.uniprot.org/uniprotkb/Q9W024" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W024", "url": "https://www.uniprot.org/uniprotkb/Q9W024" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W024", "url": "https://www.uniprot.org/uniprotkb/Q9W024" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W024", "url": "https://www.uniprot.org/uniprotkb/Q9W024" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W024", "url": "https://www.uniprot.org/uniprotkb/Q9W024" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG13801", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG13801", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6B3Q4-1", "protein_name": "OCA2 melanosomal transmembrane protein", "gene_name": "Oca2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSYLTLPGCKCLLRNLSPRVVHYPRPRAFGSGHWTSLLEKDHPVIRTISNGDMHLENKDIRLASAMLEVELHQTSALSVPTCPDPGRPLTVKPTASNYELGQADPCIPHAGEAAGKSPCVPEHAEFGSFLMKGRTHSPLSQFSSSLKDLSFKEDTPLLWNSPQKKRSQFMPVHHPEFIATEDSWESGLTVWEQKCMLGKEVADLSALASSEKGDLAGGVHLRAQVSKLGCCVRWMKITGLFVFVVLCSILFSLYPDQGKLWQLLAVSPLENYSVTLSGRADSIILQLDLAGALMPGGPSGSGKEEHVMVVVTQTDAVGNRWRRPQQVTHNWTVPLNPRSEHVVVSRTFEIVSREAVSISIQASLQQTRLVPLLLAHQFLGASVEAQVASAVAILTGVYTLIIFEIVHRTLAAMLGALAALAALAVVGDRPSLTHVVEWIDFETLALLFGMMILVAIFSETGFFDYCAVKAYQLSRGRVWAMIIMLCLMAAILSAFLDNVTTMLLFTPVTIRLCEVLNLDPRQVLIAEVIFTNIGGAATAIGDPPNVIIVSNQELRKMGLDFAGFTAHMFLGICLVLLVSFPLLRLLYWNKKLYNKEPSEIVELKHEIHVWRLTAQRISPASREETAVRGLLLEKVLALEHLLAQRLHTFHRQISQEDKNWETNIQELQRKHRISDRSLLVKCLTVLGFVISMFFLNSFVPGIHLDLGWIAILGAIWLLILADIHDFEIILHRVEWATLLFFAALFVLMEALTHLHLVEYVGEQTALLIKMVPEDQRFAAAIVLIVWVSALASSLIDNIPFTATMIPVLLNLSQDPEISLPALPLMYALALGACLGGNGTLIGASANVVCAGIAEQHGYGFSFMEFFRLGFPMMLMSCTIGMCYLLIAHVVVGWN", "length": 894 }, "evidence": [ { "id": "RGD:2318412", "url": "https://alliancegenome.org/gene/RGD:2318412#orthology", "database": "AGR" }, { "id": "MGI:97454", "url": "https://alliancegenome.org/gene/MGI:97454#orthology", "database": "AGR" }, { "id": "HGNC:8101", "url": "https://alliancegenome.org/gene/HGNC:8101#orthology", "database": "AGR" }, { "id": "FB:FBgn0035332", "url": "https://alliancegenome.org/gene/FB:FBgn0035332#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M9PN14-1", "protein_name": "P protein", "gene_name": "oca2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MYLENKSNIEVEMSQTGGQGHSSRVGRRKSDSVSGNFDELRLLEGFSGKKETQKLLQAAAMPSGHCIIYTDVHQEDRHSFNMVNLLNGKSNQANHTERTPLLKFSQNDSITYMTLHEPSLGSGEESWEASSAELERRCRLGSEVTSLSHITSPEKSENYFKLSFPIRYCLGMTRLITIFVIVVLCSLFFSMYPDRESPWRMLAVSSTESFSMNLTDFRDNSLLKLQVGGPFLGGMEAVQESQEYILIQVEQTEEAGPRRRRTQQVLYNWTIPLHSQRSDQILRTRTFEMVSSAPIQISVQAFLLDNQVVPLSMTNQSLYVTVETQVLIAGLILAGVYVLIIFEIVHRTLAAMLGSLSALAALAFIGDRPSLMTVVEWIDYETLALLFGMMILVAIFSETGFFDYCAVKAYQLSRGRVWPMIIILCLIAAILSAFLDNVTTMMLFTPVTIRLCEVLNLDPRQVLIAEVIFTNIGGAATAVGDPPNVIIVSNQDLRKKGIDFAAFTGYMFLGICLVLLTSFPFLRLLFWNKKLYNKESSEIVELKHEILVWRQTAHRINPASREETAVKCLLMQKVLNLESLLRKKLKTFQRQISQEDKNWEHNIQELQKKHRITDKVLLVKCLTVLGVVIFMFFLNSFVPAIHLDLGWIAILGALWLLVLADIQDFEIILHRVEWATLLFFAALFVLMEALAQLQLIDYIGEQTAVLIKAVPEDERLAIAIILVLWVSALASSLIDNIPFTATMIPVLINLSQDADVNLPIKPLIFALAMGACLGGNGTLIGASANVVCAGIAEQHGYGFSFMEFFRLGFPMMLMTCTIGMCYLLATHIGLHWNT", "length": 834 }, "evidence": [ { "id": "MGI:97454", "url": "https://alliancegenome.org/gene/MGI:97454#orthology", "database": "AGR" }, { "id": "HGNC:8101", "url": "https://alliancegenome.org/gene/HGNC:8101#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q04671-1", "protein_name": "P protein", "gene_name": "OCA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MHLEGRDGRRYPGAPAVELLQTSVPSGLAELVAGKRRLPRGAGGADPSHSCPRGAAGQSSWAPAGQEFASFLTKGRSHSSLPQMSSSRSKDSCFTENTPLLRNSLQEKGSRCIPVYHPEFITAEESWEDSSADWERRYLLSREVSGLSASASSEKGDLLDSPHIRLRLSKLRRCVQWLKVMGLFAFVVLCSILFSLYPDQGKLWQLLALSPLENYSVNLSSHVDSTLLQVDLAGALVASGPSRPGREEHIVVELTQADALGSRWRRPQQVTHNWTVYLNPRRSEHSVMSRTFEVLTRETVSISIRASLQQTQAVPLLMAHQYLRGSVETQVTIATAILAGVYALIIFEIVHRTLAAMLGSLAALAALAVIGDRPSLTHVVEWIDFETLALLFGMMILVAIFSETGFFDYCAVKAYRLSRGRVWAMIIMLCLIAAVLSAFLDNVTTMLLFTPVTIRLCEVLNLDPRQVLIAEVIFTNIGGAATAIGDPPNVIIVSNQELRKMGLDFAGFTAHMFIGICLVLLVCFPLLRLLYWNRKLYNKEPSEIVELKHEIHVWRLTAQRISPASREETAVRRLLLGKVLALEHLLARRLHTFHRQISQEDKNWETNIQELQKKHRISDGILLAKCLTVLGFVIFMFFLNSFVPGIHLDLGWIAILGAIWLLILADIHDFEIILHRVEWATLLFFAALFVLMEALAHLHLIEYVGEQTALLIKMVPEEQRLIAAIVLVVWVSALASSLIDNIPFTATMIPVLLNLSHDPEVGLPAPPLMYALAFGACLGGNGTLIGASANVVCAGIAEQHGYGFSFMEFFRLGFPMMVVSCTVGMCYLLVAHVVVGWN", "length": 838 }, "evidence": [ { "id": "RGD:2318412", "url": "https://alliancegenome.org/gene/RGD:2318412#orthology", "database": "AGR" }, { "id": "MGI:97454", "url": "https://alliancegenome.org/gene/MGI:97454#orthology", "database": "AGR" }, { "id": "HGNC:8101", "url": "https://alliancegenome.org/gene/HGNC:8101#orthology", "database": "AGR" }, { "id": "FB:FBgn0035332", "url": "https://alliancegenome.org/gene/FB:FBgn0035332#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q62052-1", "protein_name": "P protein", "gene_name": "Oca2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRLENKDIRLASAVLEVELHQTSALSVPTCPDPGRLLTVKPATSNYKLGQADPCIPYAGEAAGKSVCVPEHTEFGSFLVKGSSSLKDLSFKEDTPLLWNSSQKKRSQLMPVHHPEFIATEGSWENGLTAWEQKCMLGKEVADLSALASSEKRDLAGSVHLRAQVSKLGCCVRWIKITGLFVFVVLCSILFSLYPDQGKFWQLLAVSPLENYSVNLSGHADSMILQLDLAGALMAGGPSGSGKEEHVVVVVTQTDAAGNRRRRPQQLTYNWTVLLNPRSEHVVVSRTFEIVSREAVSISIQASLQQTRLVPLLLAHQFLGASVEAQVASAVAILAGVYTLIIFEIVHRTLAAMLGALAALAALAVVGDRPSLTHVVEWIDFETLALLFGMMILVAVFSETGFFDYCAVKAYQLSRGRVWAMIFMLCLMAAILSAFLDNVTTMLLFTPVTIRLCEVLNLDPRQVLIAEVIFTNIGGAATAIGDPPNVIIVSNQELRKMGLDFAGFTAHMFLGICLVLLVSFPLLRLLYWNKKLYNKEPSEIVELKHEIHVWRLTAQRISPASREETAVRGLLLEKVLALEHLLAQRLHTFHRQISQEDKNWETNIQELQRKHRISDRSLLVKCLTVLGFVISMFFLNSFVPGIHLDLGWIAILGAIWLLILADIHDFEIILHRVEWATLLFFAALFVLMEALTHLHLVEYVGEQTALLIKMVPEDQRFAAAIVLIVWVSALASSLIDNIPFTATMIPVLLNLSQDPEISLPALPLMYALALGACLGGNGTLIGASTNVVCAGIAEKHGYGFSFMEFFRLGFPVMLMSCTIGMCYLLIAHIVVGWN", "length": 833 }, "evidence": [ { "id": "RGD:2318412", "url": "https://alliancegenome.org/gene/RGD:2318412#orthology", "database": "AGR" }, { "id": "MGI:97454", "url": "https://alliancegenome.org/gene/MGI:97454#orthology", "database": "AGR" }, { "id": "HGNC:8101", "url": "https://alliancegenome.org/gene/HGNC:8101#orthology", "database": "AGR" }, { "id": "FB:FBgn0035332", "url": "https://alliancegenome.org/gene/FB:FBgn0035332#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7KRS1-1", "protein_name": "Citrate transporter-like domain-containing protein", "gene_name": "Dmel\\CG31693", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKILSNLLVINSQRLGGSRFQAWPNVRQTRSDIRRQNDGQQSSGRHVKIIHIVKMCILLLLWLGCAFIVFVFAAEQSTRSTMITVMPNKTAMTKVEPPNNALKVTLHGPVQSNGADGVDLRLEWRSSDLNVTYRRTEVWNIGISNDDTAYAKVSRNFMVKRTGGADSQAVISLESKRNSPISLHVVIDTNPMVTDMCLVCAGLLILGLYMLIIFDVIDHTFAALIIATTAVAILAILEHRPSMRAIVSFVNFEPLMLLFGLMTIVDIMATTGVFDFLVVWTYRISRGRPWPLIFFLSMLTAFLSAFLNSDIMALSLTPITIRLCEEMSLRTSYVLVVMAIFADMGGALTPLGNPPNAIVTTSPVAVAEGVDFAHFIIHMMPGVLAAMFVVFGIIYVTHRKSIFVLDQNQLDLMEERARGKKPPSQETLDRIALLKGSLPGKYWLRPVEGYPETLAELEASSRILDKPLLVRCCIALIFAFLCMLLHSIPKVADGASLGWVTLLAAFLLIILDDKNDLNATLGIIQWTILLFIAALFVLSEAVDQLGFFEWLGDRTVGFLRSLEPQNQIAVTTMVILWTTALLTIFIDNAAVTIFMLKFSIEMASNDDIPLPPMFWALTFGACFGGNGSLFGAVSNEIIALIALQHGYKISFWHFFAIGFPLMLVTMVIGSGYLLIAHSVLSWNLHLVR", "length": 688 }, "evidence": [ { "id": "RGD:2318412", "url": "https://alliancegenome.org/gene/RGD:2318412#orthology", "database": "AGR" }, { "id": "MGI:97454", "url": "https://alliancegenome.org/gene/MGI:97454#orthology", "database": "AGR" }, { "id": "HGNC:8101", "url": "https://alliancegenome.org/gene/HGNC:8101#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VR47-1", "protein_name": "Hoepel1, isoform J", "gene_name": "hoe1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTSPYGYSKPTFMITDHTRDPYHLQPGDDDDDRDEDEERQTKLQEIISWLHLNAKHRSKCEVTEGALQVWRTLPERIRQDPSLASFRQEHERLHGDVDQLHAEESELRVQNGHHEETALANQPFTQIGINVTNEAGQVRVLDGRDLENNNDDQHDEAEPHAKSLIRKYLIWFKIAILLVVWCVFTAFLMSNNEHVDQLSLISVPRNSSPRVFPIATASLQRIGLGLRGPFRLQENELAINASVPLPLLQVQVMRSYFDGEGMEIYIENASQVWQLDVVYPDLIDATRDTKKQRTFELSPTDPLWLAQANRTELSFEFTSSIEGELPLQLNVDESPIYKRDGVIYAAAVLCGLYVMIIWEIVNRTFAAIIASTLSVGILAALNSRPSMATIMGWIDVETLLLLFGMMILVAILSETGVFDYLAVYAYKITNGHVWPLINCLCLFTAVLSSFLDNVTTVLLMTPVTIRLCEVMCLNPVPILMCMVIYSNIGGALTPVGDPPNVIIASNSYISKNGVNFAVFTLHMLPGVLLVMVQTYIQLRFKFRNISDLQFKDSPEVEELRHEIHVWKRAAASLSAYSKDEELVRQTLMKKVNRLKRSLKKRMTAVIEPAPNYQQTLANLQAKYPIRNKPLLIKCSAALVFVISLFFLHSVPELQRLSLGWTALLGAIFLIILADIEDMEAILARVEWSTLLFFAALFILMEALTELGLIEWIGNMTEGIILGVGEDRRLMVAILIILWVSAVASAFVDNIPLTTMMVKITISLAQNSTLNLPLQPLVWALALGACLGGNGTLIGASANVVCAGVAEQHGYKFTFLQFFKVGFPIMIGSIIVTTGYLLVSHSLFAWH", "length": 846 }, "evidence": [ { "id": "RGD:2318412", "url": "https://alliancegenome.org/gene/RGD:2318412#orthology", "database": "AGR" }, { "id": "MGI:97454", "url": "https://alliancegenome.org/gene/MGI:97454#orthology", "database": "AGR" }, { "id": "HGNC:8101", "url": "https://alliancegenome.org/gene/HGNC:8101#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VR48-1", "protein_name": "Hoepel2", "gene_name": "hoe2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGLRDTIRNLRPASPGREKSSGIELQQRSPRGACHHNQVAAVQVTEQSLQVWRALPAEIRHDPSMASFQMENERIHGSSGGATDDEDEDGYEEVDMKNVSRIQDEPGSSFAGSDFLDIKNRPGDENATDDEVTTHSDHEAANGGPGNAKSQARRIHHKSKRSKEQRQRDKLWKRGGLLVFWILSAVVLISVGEKHLLEKTIDVPMGEEGKFFKLLQKPTGDFRLKIHGAFRELSTLDAPENETLSFGFLTVQPQVSTYIGENHSQVFQDILPAWRLPLLSEEELMLRAPAVTTNRTYQMTQELDEMLAGKNSEFRLHIYSDVEVDLAIVLNYNPLIVNARTGSILAGVILLIFYALLVWELFERTFVAMICSILSVTTLACFNDRPNMDEIIQWMDMELLTLLFCMMLLILILTETGVFDYLAVFCFEISGGKIWPMIYSLCLVTCLVSSVLDNMTTVLLLTPVAIRLCEVMQLDPLPVVMGIIVHANIGGALTPIGDPISIIVSTNHFIVDNDVTFPTFVAHTFPGVILAVIQSCVYLRLFYHNIDALRLNEPKEMSELRREMKVWQRALNAVASCSKDAQLVRGTLQAKIKQLKRTLRRLQKGVGSTEVYTNTLDELKQKYPIKNKTLLLQSAGALLFVIVCFFIQSVPHWRTLPLGWVALLGVILLLIILNRDDMEHLMHRIEWTTLLFFAAMFVMMECVERLGIFACISELTEHVILSVGKSHRLAMAIFMILWMSALASSILDSIPVAAIMVKLVTSLVAKPSLGLPLQPLVWALTLGASMGGNGTLYGASANVIAAGIAEQHGYKLSFTRYLRTVFPMMLGQITLMTVYLLVAHVVFEWH", "length": 846 }, "evidence": [ { "id": "RGD:2318412", "url": "https://alliancegenome.org/gene/RGD:2318412#orthology", "database": "AGR" }, { "id": "MGI:97454", "url": "https://alliancegenome.org/gene/MGI:97454#orthology", "database": "AGR" }, { "id": "HGNC:8101", "url": "https://alliancegenome.org/gene/HGNC:8101#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VU30-1", "protein_name": "Citrate transporter-like domain-containing protein", "gene_name": "Dmel\\CG11262", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKFLSDIFRVADLCQIDGVRQAWPSSHQSSIPRRLRMPEQPEPNYLDEPETISVGRFIFKIIRIGALLLIWAFFTYILVRNATTPDLTSVVTVLPNETVLRRLSVPHDATQITLKGPIDLQLQKHESVIMETPHVGVRVEWRDSELKTKFWSSDMWIVYLAEQSQAFTKTSKTVQISEVSNAQAVISLESRSEEPVALLMVVSVYPLVTENGVLYAALLLIGFYILIVFELTDRTFAALMMATTGIAILTALGNRPTLETIISWIDFETLILLLGMMILVAIMSETGVFDWMAVLAYRISKGNPWPMLLLLSSITAIMSCMLDNVTMLLLMAPIAIRLCEAMAVQTPLVLIVVVMYSNIGGTLTPVGDPPNVIIATNSEVISAGVDFLDFTIHMLPGVLLAAVAGYAVMYVTMRKSLFKLEEQQLELAAERENSRRRSSADITARAEEMRIRQPTGRQLLKPAENYFQTLAHLEAHHRIRDKTLLIKCLFTLCFVIIFFLLHSLPFMHGATLGWVAILAAFLLLILAKMNDIEAILDQVEWSALLFLAALFVLTEAVDKLGFIRWLCDLTVKVIMSVEERYQTTVAILIIIWMSAILAAFVGNVPVTTMLLRLNIELHRNDAISVPLTPLIWALSYGACFGGNGTLIGASANVVAAAIAQQYGYKISFVQFFIYGFPMMLTSIFLATVYLLIAHSLFAWHKT", "length": 702 }, "evidence": [ { "id": "RGD:2318412", "url": "https://alliancegenome.org/gene/RGD:2318412#orthology", "database": "AGR" }, { "id": "MGI:97454", "url": "https://alliancegenome.org/gene/MGI:97454#orthology", "database": "AGR" }, { "id": "HGNC:8101", "url": "https://alliancegenome.org/gene/HGNC:8101#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9W024", "url": "https://www.uniprot.org/uniprotkb/Q9W024" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "monoatomic ion transmembrane transporter activity", "id": "GO:0015075", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015075", "evidence": [ { "database": "UniProtKB", "id": "Q9W024", "url": "https://www.uniprot.org/uniprotkb/Q9W024" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 113, "end_pos": 115, "annotation": "n_glycosylation_sequon" }, { "start_pos": 195, "end_pos": 197, "annotation": "n_glycosylation_sequon" }, { "start_pos": 316, "end_pos": 318, "annotation": "n_glycosylation_sequon" }, { "start_pos": 62, "end_pos": 64, "annotation": "n_glycosylation_sequon" }, { "start_pos": 633, "end_pos": 635, "annotation": "n_glycosylation_sequon" }, { "start_pos": 97, "end_pos": 99, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9W024", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W024" }, { "id": "PF03600", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03600" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Citrate transporter-like", "eco_id": "ECO_0000259", "start_pos": 216, "end_pos": 627, "start_aa": "Tyr", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 113, "end_pos": 115 }, { "start_pos": 195, "end_pos": 197 }, { "start_pos": 316, "end_pos": 318 }, { "start_pos": 62, "end_pos": 64 }, { "start_pos": 633, "end_pos": 635 }, { "start_pos": 97, "end_pos": 99 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9W041-1", "uniprot_ac": "Q9W041", "uniprot_id": "Q9W041_DROME", "mass": { "chemical_mass": 51335.0, "monoisotopic_mass": 51335.0 }, "refseq": { "ac": "NP_647699", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647699" }, "gene_names": [ { "name": "15878", "type": "recommended", "evidence": [ { "id": "Q9W041", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W041" } ] }, { "name": "15878", "type": "synonym", "evidence": [ { "id": "NP_647699", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647699" } ] }, { "name": "CG15878", "type": "synonym", "evidence": [ { "id": "NP_647699", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647699" }, { "id": "Q9W041", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W041" } ] }, { "name": "Dmel\\CG15878", "type": "synonym", "evidence": [ { "id": "NP_647699", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647699" }, { "id": "Q9W041", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W041" } ] }, { "name": "Dmel_CG15878", "type": "synonym", "evidence": [ { "id": "Q9W041", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W041" } ] } ], "protein_names": [ { "name": "CG15878-PA", "type": "synonym", 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"MSFHRINVKQASIAARQRQSRTTRMTRHTIFNLKRPITFQVRKSLVEYVDMELADMDTSVFYQRIFILAKNCHLTPVVSNEELLADAVVEQAEPEPDEAAPIQFMEDVIFDNTETESPMNTTADPAPIPAPEEGATETAEVVTHMFRFSEDDPEEDFVEEEELEMDTQAPDQPKDFFAIFSERLQELHKQCKALAITPDPMCGLFLHMGEYSMLMLESSEDMIGCFTRALADCCETFWLMNRVFQIEDHVQELYTKELMFRRIPSVFLNEKFPTSTPTDEYLMGKQHLIIKDKLLTICRLLSEGQQVDPDGISTRESDMEDDMPKSKSKSSILSEHLPVEVFRKHLPEIQRIELVLASTRFYYELGEFAWLYGRVPFSPDEDGLFWPIQSNYTPPNIFRRTPYDINLTFGEYAAEASKRKTQGSLVGSIADEEEAPPNEETPPKTE", "length": 446, "header": "tr|Q9W041-1|Q9W041_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=15878 PE=4 SV=1 CANONICAL=Q9W041-1" }, "isoforms": [ { "isoform_ac": "Q9W041-1", "url": "https://www.uniprot.org/uniprotkb/Q9W041/entry#Q9W041-1", "sequence": { "sequence": "MSFHRINVKQASIAARQRQSRTTRMTRHTIFNLKRPITFQVRKSLVEYVDMELADMDTSVFYQRIFILAKNCHLTPVVSNEELLADAVVEQAEPEPDEAAPIQFMEDVIFDNTETESPMNTTADPAPIPAPEEGATETAEVVTHMFRFSEDDPEEDFVEEEELEMDTQAPDQPKDFFAIFSERLQELHKQCKALAITPDPMCGLFLHMGEYSMLMLESSEDMIGCFTRALADCCETFWLMNRVFQIEDHVQELYTKELMFRRIPSVFLNEKFPTSTPTDEYLMGKQHLIIKDKLLTICRLLSEGQQVDPDGISTRESDMEDDMPKSKSKSSILSEHLPVEVFRKHLPEIQRIELVLASTRFYYELGEFAWLYGRVPFSPDEDGLFWPIQSNYTPPNIFRRTPYDINLTFGEYAAEASKRKTQGSLVGSIADEEEAPPNEETPPKTE", "length": 446, "header": "tr|Q9W041-1|Q9W041_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=15878 PE=4 SV=1 CANONICAL=Q9W041-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W041", "url": "https://www.uniprot.org/uniprotkb/Q9W041" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W041", "url": "https://www.uniprot.org/uniprotkb/Q9W041" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W041", "url": "https://www.uniprot.org/uniprotkb/Q9W041" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W041", "url": "https://www.uniprot.org/uniprotkb/Q9W041" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W041", "url": "https://www.uniprot.org/uniprotkb/Q9W041" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W041", "url": "https://www.uniprot.org/uniprotkb/Q9W041" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W041", "url": "https://www.uniprot.org/uniprotkb/Q9W041" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W041", "url": "https://www.uniprot.org/uniprotkb/Q9W041" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W041", "url": "https://www.uniprot.org/uniprotkb/Q9W041" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"Q9W045", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W045" } ] }, { "name": "Dmel\\CG15820", "type": "synonym", "evidence": [ { "id": "NP_647696", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647696" }, { "id": "Q9W045", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W045" } ] }, { "name": "Dmel_CG15820", "type": "synonym", "evidence": [ { "id": "Q9W045", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W045" } ] } ], "protein_names": [ { "name": "AB hydrolase-1 domain-containing protein", "type": "recommended", "evidence": [ { "id": "Q9W045", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W045/entry#names_and_taxonomy" } ] }, { "name": "CG15820-PA", "type": "synonym", "evidence": [ { "id": "NP_647696", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647696" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_647696", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647696" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W045", "url": "https://www.uniprot.org/uniprotkb/Q9W045" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "BcDNA:SD08776", "url": "https://www.uniprot.org/uniprotkb/Q9W045", "locus": { "chromosome": "3L", "start_pos": 2172995, "end_pos": 2174332, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0035312", "url": "https://www.ensemblgenomes.org/id/FBgn0035312" } ] } } ], "crossref": [ { "id": "FB:FBgn0035312", "url": "https://alliancegenome.org/gene/FB:FBgn0035312", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0035312", "url": "https://bgee.org/?page=gene&gene_id=FBgn0035312", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0035312", "url": "https://flybase.org/reports/FBgn0035312", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "38277", "url": "https://www.ncbi.nlm.nih.gov/gene/38277", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050266", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050266", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG15820", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG15820", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MYPEKVF", "url": "https://omabrowser.org/oma/group/MYPEKVF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W045", "url": "https://www.orthodb.org/?gene=Q9W045", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43798", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43798", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43798:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43798:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00561", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00561", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_647696", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647696", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W045", "url": "https://www.uniprot.org/uniprotkb/Q9W045", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W045-1", "url": "https://www.uniprot.org/uniprotkb/Q9W045-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHKRLQYEEVMIPAPWGHIAGRWYGNRADRPILAIHGWLDNLGTFDRLIPLLPDYIGVLCIDLPGHGRSSRLPPGVPYNVYDYVFIIPRVMKEFGWSKVSLMGHSLGGVMSFMYAAMAPSTVDMIISLDVLLPRRIEDPSKLTKDIEGYLLEERRQADGTEHEPPSFTLSKLRETLARNSNNSVPQHLADHMLHRQVAKSNMYPEKVFFSRDGRVKFYHIFDIENGLALEMARRIEKKPYLVIKGSLSPFVGPRCNETMSILSHDNPNFEFYEVEGGKHHVHLHAAEECARYIVPFIRNHRPPRSSKL", "length": 308, "header": "tr|Q9W045-1|Q9W045_DROME Isoform 1 of AB hydrolase-1 domain-containing protein OS=Drosophila melanogaster OX=7227 GN=BcDNA:SD08776 PE=3 SV=2 CANONICAL=Q9W045-1" }, "isoforms": [ { "isoform_ac": "Q9W045-1", "url": "https://www.uniprot.org/uniprotkb/Q9W045/entry#Q9W045-1", "sequence": { "sequence": "MHKRLQYEEVMIPAPWGHIAGRWYGNRADRPILAIHGWLDNLGTFDRLIPLLPDYIGVLCIDLPGHGRSSRLPPGVPYNVYDYVFIIPRVMKEFGWSKVSLMGHSLGGVMSFMYAAMAPSTVDMIISLDVLLPRRIEDPSKLTKDIEGYLLEERRQADGTEHEPPSFTLSKLRETLARNSNNSVPQHLADHMLHRQVAKSNMYPEKVFFSRDGRVKFYHIFDIENGLALEMARRIEKKPYLVIKGSLSPFVGPRCNETMSILSHDNPNFEFYEVEGGKHHVHLHAAEECARYIVPFIRNHRPPRSSKL", "length": 308, "header": "tr|Q9W045-1|Q9W045_DROME Isoform 1 of AB hydrolase-1 domain-containing protein OS=Drosophila melanogaster OX=7227 GN=BcDNA:SD08776 PE=3 SV=2 CANONICAL=Q9W045-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W045", "url": "https://www.uniprot.org/uniprotkb/Q9W045" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W045", "url": "https://www.uniprot.org/uniprotkb/Q9W045" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W045", "url": "https://www.uniprot.org/uniprotkb/Q9W045" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W045", "url": "https://www.uniprot.org/uniprotkb/Q9W045" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W045", "url": "https://www.uniprot.org/uniprotkb/Q9W045" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W045", "url": "https://www.uniprot.org/uniprotkb/Q9W045" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W045", "url": "https://www.uniprot.org/uniprotkb/Q9W045" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W045", "url": "https://www.uniprot.org/uniprotkb/Q9W045" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W045", "url": "https://www.uniprot.org/uniprotkb/Q9W045" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W045", "url": "https://www.uniprot.org/uniprotkb/Q9W045" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W045", "url": "https://www.uniprot.org/uniprotkb/Q9W045" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG15820", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG15820", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A2BGU9-1", "protein_name": "Serine hydrolase-like protein", "gene_name": "serhl", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLPAFMSLRHFTTTTMRRAASEFRMPVPWGELRGQVWGPSHGRPVLCLHGWADNSGTFNTLVPLLPNDWRFVAIDFPGHGLSSHRPDGCFYAFPFYVADVRRVVEALQWKRFSIIGHSMGGNVAGMFSALYPEMVESVVLLDTYGFLPTEVTDMFTNMRKGINDQIQYDNMANERKERVYTYEKAKERLKVANPYLSDQSADILLERAVREVDGGFVFTRDFRINLKNIIYINIDQCLHVLSQVKAKVMLLLAKDGLFKTFTLPDGYADRICKSWTDQKATFVEVEGDHHVHLNNPEAVSSVITDFLQPQSPDQTESQSGNQTSRL", "length": 326 }, "evidence": [ { "id": "HGNC:14408", "url": "https://alliancegenome.org/gene/HGNC:14408#orthology", "database": "AGR" }, { "id": "HGNC:29446", "url": "https://alliancegenome.org/gene/HGNC:29446#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-1368", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1368#orthology", "database": "AGR" }, { "id": "MGI:1890404", "url": "https://alliancegenome.org/gene/MGI:1890404#orthology", "database": "AGR" }, { "id": "RGD:1563386", "url": "https://alliancegenome.org/gene/RGD:1563386#orthology", "database": "AGR" }, { "id": "FB:FBgn0035312", "url": "https://alliancegenome.org/gene/FB:FBgn0035312#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D4A071-1", "protein_name": "Serine hydrolase-like 2", "gene_name": "Serhl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPLAYSSRWSRHSSPSPLGLLSELKLAVPWGHIAVKVWGLQKNPPVLCLHGWLDNANSFDKLIPFLPKDFCYVAMDFGGHGLSTHYSPGLPYYHHNFVSEVRRVVSAFKWTRLSLLGHSFGGVVGGLFACMFPEMVDKLILLDSTPLLMDLNEVENIMTYRRKNIEQTLKVEDSQKPPGIFSPEEMLHELLTKNSHLNEDCGELLLQRGTTKVAEGLVLNRDQRLSWPQYSFDFMGKELTMHSLRRLQASVLIIKALDGYYDVRRENDLNKASFLLMLDILRSTLKERFQFVEIPGNHYIHMNKPQIVADIIRSFLQGPPRTTPSRL", "length": 328 }, "evidence": [ { "id": "HGNC:14408", "url": "https://alliancegenome.org/gene/HGNC:14408#orthology", "database": "AGR" }, { "id": "HGNC:29446", "url": "https://alliancegenome.org/gene/HGNC:29446#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-1368", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1368#orthology", "database": "AGR" }, { "id": "MGI:1890404", "url": "https://alliancegenome.org/gene/MGI:1890404#orthology", "database": "AGR" }, { "id": "RGD:1563386", "url": "https://alliancegenome.org/gene/RGD:1563386#orthology", "database": "AGR" }, { "id": "FB:FBgn0035312", "url": "https://alliancegenome.org/gene/FB:FBgn0035312#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O18391-1", "protein_name": "Probable serine hydrolase", "gene_name": "kraken", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGQTRVAATTAAQSPAAELSPETNGQTEEPLQLLGEDSWEEFSIAVPWGTVEAKWWGSKERQPIIALHGWQDNCGSFDRLCPLLPADTSILAIDLPGHGKSSHYPMGMQYFIFWDGICLIRRIVRKYNWKNVTLLGHSLGGALTFMYAASFPTEVEKLINIDIAGPTVRGTQRMAEGTGRALDKFLDYETLPESKQPCYSYDEMIKLVLDAYDGSVDEPSVRVLMNRGMRHNPSKNGYLFARDLRLKVSLLGMFTAEQTLAYARQIRCRVLNIRGIPGMKFETPQVYADVIATLRENAAKVVYVEVPGTHHLHLVTPDRVAPHIIRFLKEA", "length": 331 }, "evidence": [ { "id": "HGNC:14408", "url": "https://alliancegenome.org/gene/HGNC:14408#orthology", "database": "AGR" }, { "id": "HGNC:29446", "url": "https://alliancegenome.org/gene/HGNC:29446#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-1368", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1368#orthology", "database": "AGR" }, { "id": "MGI:1890404", "url": "https://alliancegenome.org/gene/MGI:1890404#orthology", "database": "AGR" }, { "id": "RGD:1563386", "url": "https://alliancegenome.org/gene/RGD:1563386#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9EPB5-1", "protein_name": "Serine hydrolase-like protein", "gene_name": "Serhl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLHSELKLAVPWGHIALKVWGSQKNPPVLCLHGWLDNANSFDRLIPLLPQDFCYMAMDFGGHGLSSHYNPGLPYYQQNFVSEVRRVATAFKWNQFTLLGHSFGGCVGGTFACMFPEMVDKLILLDSTPFFLDSNEMENILTYRRRNIEHTLQVEASQKKSLRAVSPEEMLQGFLNNNSHLDKDCGELILQRGTTKVDAGLVLNRDRRISWPENSFDFVSKEMFVHSAKSLQASVLMIKALQGYYDVRRANDADKAPMHFMVDTLRSTLKERFQFVEVPGNHYIHMNKPQVVAGVVGPFLQGLQRMTSARL", "length": 311 }, "evidence": [ { "id": "HGNC:14408", "url": "https://alliancegenome.org/gene/HGNC:14408#orthology", "database": "AGR" }, { "id": "HGNC:29446", "url": "https://alliancegenome.org/gene/HGNC:29446#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-1368", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1368#orthology", "database": "AGR" }, { "id": "MGI:1890404", "url": "https://alliancegenome.org/gene/MGI:1890404#orthology", "database": "AGR" }, { "id": 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"https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1368#orthology", "database": "AGR" }, { "id": "MGI:1890404", "url": "https://alliancegenome.org/gene/MGI:1890404#orthology", "database": "AGR" }, { "id": "RGD:1563386", "url": "https://alliancegenome.org/gene/RGD:1563386#orthology", "database": "AGR" }, { "id": "FB:FBgn0035312", "url": "https://alliancegenome.org/gene/FB:FBgn0035312#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9NQF3-1", "protein_name": "Serine hydrolase-like protein", "gene_name": "SERHL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAENAAPGLISELKLAVPWGHIAAKAWGSLQGPPVLCLHGWLDNASSFDRLIPLLPQDFYYVAMDFGGHGLSSHYSPGVPYYLQTFVSEIRRVVAALKWNRFSILGHSFGGVVGGMFFCTFPEMVDKLILLDTPLFLLESDEMENLLTYKRRAIEHVLQVEASQEPSHVFSLKQLLQRQRTALTSSAGSCVRIPSGSCRPMSC", "length": 203 }, "evidence": [ { "id": "HGNC:14408", "url": "https://alliancegenome.org/gene/HGNC:14408#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-1368", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1368#orthology", "database": "AGR" }, { "id": "MGI:1890404", "url": "https://alliancegenome.org/gene/MGI:1890404#orthology", "database": "AGR" }, { "id": "RGD:1563386", "url": "https://alliancegenome.org/gene/RGD:1563386#orthology", "database": "AGR" }, { "id": "FB:FBgn0035312", "url": "https://alliancegenome.org/gene/FB:FBgn0035312#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VP50-1", "protein_name": "AB hydrolase-1 domain-containing protein", "gene_name": "Dmel\\CG7632", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKVSRGLFLLKQLPNVRNSSSGPTKPFKILNKHFDEISIPVPWGHISGKWYGPKHVRPIVGMHGWQDNAGTFDTLAPLLPSHLSFLSIDAPGHGLSSWLPPGTSYHSIDLVLITRRLMEEYNWDKISILAHSMSSINGFVFSALFPDKVDLFVGLDVLKPPVRSARGIVDSLTERIESALKLERRLKSGSEPPAYDWDQLVTRLHEGSNKSVSIDACKYLLQRNCKPSTHEPHKYYFSRDNRLKSSLFYTLHQEVPMEMARRIKCPHLFIKALQAPYYERKEYFDEVLAELQKNPLFEYHEVEGTHHVHLNEPEKVAPIINSFINRYRPL", "length": 330 }, "evidence": [ { "id": "HGNC:14408", "url": "https://alliancegenome.org/gene/HGNC:14408#orthology", "database": "AGR" }, { "id": "HGNC:29446", "url": "https://alliancegenome.org/gene/HGNC:29446#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-1368", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1368#orthology", "database": "AGR" }, { "id": "MGI:1890404", "url": "https://alliancegenome.org/gene/MGI:1890404#orthology", "database": "AGR" }, { "id": "RGD:1563386", "url": "https://alliancegenome.org/gene/RGD:1563386#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VP51-1", "protein_name": "AB hydrolase-1 domain-containing protein", "gene_name": "Dmel\\CG11309", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDTDDNSSGTITGSDLGQRYRHAGDLTGEAPTRPRANIWCSKKYFAEISITVPWGHISGKWYGPQNVQPILGLHGWQDNAGTFDRLMPLLSPDVAFLAIDLPGHGLSSRLPDGCYYNSVDNLYVIRLIMKQYKWEKVSLVGHSMSSIICFVFAAVFPDKVDMIIGIDALKPHQRPYPSVIRTMETRLDEFLREDERNRSKNEPPSYTYDELIERVYIGTFHSVNKEHCKHLMARNIGKSEKYPDKYFFCRDRRLKFYNYAIGSQELCVEMANRITCPYLFIKAAQSSYFEDKKYYDEVLDVLLKKPNFEYLEVNGSHHVHMNDPEAIIAPVNNFIQRFGPAAAAASRQKAKEAKESKL", "length": 358 }, "evidence": [ { "id": "HGNC:14408", "url": "https://alliancegenome.org/gene/HGNC:14408#orthology", "database": "AGR" }, { "id": "HGNC:29446", "url": "https://alliancegenome.org/gene/HGNC:29446#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-1368", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1368#orthology", "database": "AGR" }, { "id": "MGI:1890404", "url": 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"https://alliancegenome.org/gene/HGNC:29446#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-1368", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1368#orthology", "database": "AGR" }, { "id": "MGI:1890404", "url": "https://alliancegenome.org/gene/MGI:1890404#orthology", "database": "AGR" }, { "id": "RGD:1563386", "url": "https://alliancegenome.org/gene/RGD:1563386#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W048-1", "protein_name": "AB hydrolase-1 domain-containing protein", "gene_name": "Dmel\\CG15879", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSLSDFKEVRIPAPWGHISGRWYGNRTERPILAIHGWLDNLGTFDRLIPLLPDYIGVLCIDLPGHGRSAHIQPGMHYAVNDYVLIIPRVMKEYGWSKVSLMGHSLGGIISFVYTSLAPDTVDMVISLDILLPLSKDPKTVIKYLNHSLDKHLVEEERQVEGNLHEPPSYTLAQLTQVLAKGSDNSVTPEFAQHLLHRQVSKSQLYPDRFFFSRDGRVKYYSHLQMEPEFGEALVKRIRRIPCLIIKGSKSDFVEARTEKAVAILRQNNPHFEFYEVEGGTHHVHLHAAEECARYIVPFIRHHRPPALTSWSLSGKEEHLSAEEKRRQQERFFKRSTHAKSKL", "length": 342 }, "evidence": [ { "id": "HGNC:14408", "url": "https://alliancegenome.org/gene/HGNC:14408#orthology", "database": "AGR" }, { "id": "HGNC:29446", "url": "https://alliancegenome.org/gene/HGNC:29446#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-1368", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1368#orthology", "database": "AGR" }, { "id": "MGI:1890404", "url": "https://alliancegenome.org/gene/MGI:1890404#orthology", "database": "AGR" }, { "id": "RGD:1563386", "url": "https://alliancegenome.org/gene/RGD:1563386#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "Q9W045", "url": "https://www.uniprot.org/uniprotkb/Q9W045" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 181, "end_pos": 183, "annotation": "n_glycosylation_sequon" }, { "start_pos": 256, "end_pos": 258, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9W045", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W045" }, { "id": "PF00561", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00561" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AB hydrolase-1", "eco_id": "ECO_0000259", "start_pos": 31, "end_pos": 283, "start_aa": "Pro", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 181, "end_pos": 183 }, { "start_pos": 256, "end_pos": 258 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { 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"https://www.ncbi.nlm.nih.gov/protein/NP_001286912" }, "gene_names": [ { "name": "LD30049", "type": "recommended", "evidence": [ { "id": "Q9W047", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W047" } ] }, { "name": "BEST:LD30049", "type": "synonym", "evidence": [ { "id": "NP_001286912", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001286912" }, { "id": "Q9W047", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W047" } ] }, { "name": "CG5704", "type": "synonym", "evidence": [ { "id": "NP_001286912", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001286912" }, { "id": "Q9W047", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W047" } ] }, { "name": "Dmel\\CG5704", "type": "synonym", "evidence": [ { "id": "NP_001286912", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001286912" }, { "id": "Q9W047", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W047" } ] }, { "name": "Dmel_CG5704", "type": "synonym", "evidence": [ { "id": "Q9W047", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W047" } ] }, { "name": "LD30049", "type": "synonym", "evidence": [ { "id": "NP_001286912", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001286912" } ] } ], "protein_names": [ { "name": "AB hydrolase-1 domain-containing protein", "type": "recommended", "evidence": [ { "id": "Q9W047", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W047/entry#names_and_taxonomy" } ] }, { "name": "CG5704-PB", "type": "synonym", "evidence": [ { "id": "NP_001286912", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001286912" } ] }, { "name": "uncharacterized protein, isoform B", "type": "synonym", "evidence": [ { "id": "NP_001286912", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001286912" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W047", "url": "https://www.uniprot.org/uniprotkb/Q9W047" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "LD30049", "url": "https://www.uniprot.org/uniprotkb/Q9W047", "locus": { "chromosome": "3L", "start_pos": 2169553, "end_pos": 2170971, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0026570", "url": "https://www.ensemblgenomes.org/id/FBgn0026570" } ] } } ], "crossref": [ { "id": "FB:FBgn0026570", "url": "https://alliancegenome.org/gene/FB:FBgn0026570", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0026570", "url": "https://bgee.org/?page=gene&gene_id=FBgn0026570", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0026570", "url": "https://flybase.org/reports/FBgn0026570", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "48613", "url": "https://www.ncbi.nlm.nih.gov/gene/48613", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050266", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050266", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG5704", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG5704", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RSNEAIN", "url": "https://omabrowser.org/oma/group/RSNEAIN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W047", "url": "https://www.orthodb.org/?gene=Q9W047", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43798", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43798", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43798:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43798:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00561", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00561", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001286912", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001286912", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W047", "url": "https://www.uniprot.org/uniprotkb/Q9W047", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W047-1", "url": "https://www.uniprot.org/uniprotkb/Q9W047-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGTLSLSDFEAVKIPVPWGHISGRWYGNRNERPILAIHGWLDNLGTFDRLIPLLPDYLGVLCIDLPGHGRSSHLPPGMYYSVYEYVFTIPLVMKEYGWSKVSLIGHSLGGVLSFIYASLAPHTVDMIVSLDILLPLRNDIDYMDLSIEKQLVNVERQKLGNYIEPPSYTHNQLGKVLAAGSFNSVSPELAKHLLHRQLAKSKLYPERFYFTRDIRVKYYHYIDIDDSLGAEMARRIIKKPYLIIKGSLSPYLSVRNNEAISILAKDNPHFEFYEVENGTHHLHLHAAEECAGYIVPFIQHHRPPAMTSWTVAGKEDRSRKPKRFFTWTNKKRSKL", "length": 335, "header": "tr|Q9W047-1|Q9W047_DROME Isoform 1 of AB hydrolase-1 domain-containing protein OS=Drosophila melanogaster OX=7227 GN=LD30049 PE=3 SV=1 CANONICAL=Q9W047-1" }, "isoforms": [ { "isoform_ac": "Q9W047-1", "url": "https://www.uniprot.org/uniprotkb/Q9W047/entry#Q9W047-1", "sequence": { "sequence": "MGTLSLSDFEAVKIPVPWGHISGRWYGNRNERPILAIHGWLDNLGTFDRLIPLLPDYLGVLCIDLPGHGRSSHLPPGMYYSVYEYVFTIPLVMKEYGWSKVSLIGHSLGGVLSFIYASLAPHTVDMIVSLDILLPLRNDIDYMDLSIEKQLVNVERQKLGNYIEPPSYTHNQLGKVLAAGSFNSVSPELAKHLLHRQLAKSKLYPERFYFTRDIRVKYYHYIDIDDSLGAEMARRIIKKPYLIIKGSLSPYLSVRNNEAISILAKDNPHFEFYEVENGTHHLHLHAAEECAGYIVPFIQHHRPPAMTSWTVAGKEDRSRKPKRFFTWTNKKRSKL", "length": 335, "header": "tr|Q9W047-1|Q9W047_DROME Isoform 1 of AB hydrolase-1 domain-containing protein OS=Drosophila melanogaster OX=7227 GN=LD30049 PE=3 SV=1 CANONICAL=Q9W047-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W047", "url": "https://www.uniprot.org/uniprotkb/Q9W047" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W047", "url": "https://www.uniprot.org/uniprotkb/Q9W047" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W047", "url": "https://www.uniprot.org/uniprotkb/Q9W047" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W047", "url": "https://www.uniprot.org/uniprotkb/Q9W047" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W047", "url": "https://www.uniprot.org/uniprotkb/Q9W047" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W047", "url": "https://www.uniprot.org/uniprotkb/Q9W047" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W047", "url": "https://www.uniprot.org/uniprotkb/Q9W047" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W047", "url": "https://www.uniprot.org/uniprotkb/Q9W047" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W047", "url": "https://www.uniprot.org/uniprotkb/Q9W047" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W047", "url": "https://www.uniprot.org/uniprotkb/Q9W047" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W047", "url": "https://www.uniprot.org/uniprotkb/Q9W047" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG5704", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG5704", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A2BGU9-1", "protein_name": "Serine hydrolase-like protein", "gene_name": "serhl", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLPAFMSLRHFTTTTMRRAASEFRMPVPWGELRGQVWGPSHGRPVLCLHGWADNSGTFNTLVPLLPNDWRFVAIDFPGHGLSSHRPDGCFYAFPFYVADVRRVVEALQWKRFSIIGHSMGGNVAGMFSALYPEMVESVVLLDTYGFLPTEVTDMFTNMRKGINDQIQYDNMANERKERVYTYEKAKERLKVANPYLSDQSADILLERAVREVDGGFVFTRDFRINLKNIIYINIDQCLHVLSQVKAKVMLLLAKDGLFKTFTLPDGYADRICKSWTDQKATFVEVEGDHHVHLNNPEAVSSVITDFLQPQSPDQTESQSGNQTSRL", "length": 326 }, "evidence": [ { "id": "HGNC:14408", "url": "https://alliancegenome.org/gene/HGNC:14408#orthology", "database": "AGR" }, { "id": "HGNC:29446", "url": "https://alliancegenome.org/gene/HGNC:29446#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-1368", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1368#orthology", "database": "AGR" }, { "id": "MGI:1890404", "url": "https://alliancegenome.org/gene/MGI:1890404#orthology", "database": "AGR" }, { "id": "RGD:1563386", "url": "https://alliancegenome.org/gene/RGD:1563386#orthology", "database": "AGR" }, { "id": "FB:FBgn0026570", "url": "https://alliancegenome.org/gene/FB:FBgn0026570#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D4A071-1", "protein_name": "Serine hydrolase-like 2", "gene_name": "Serhl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPLAYSSRWSRHSSPSPLGLLSELKLAVPWGHIAVKVWGLQKNPPVLCLHGWLDNANSFDKLIPFLPKDFCYVAMDFGGHGLSTHYSPGLPYYHHNFVSEVRRVVSAFKWTRLSLLGHSFGGVVGGLFACMFPEMVDKLILLDSTPLLMDLNEVENIMTYRRKNIEQTLKVEDSQKPPGIFSPEEMLHELLTKNSHLNEDCGELLLQRGTTKVAEGLVLNRDQRLSWPQYSFDFMGKELTMHSLRRLQASVLIIKALDGYYDVRRENDLNKASFLLMLDILRSTLKERFQFVEIPGNHYIHMNKPQIVADIIRSFLQGPPRTTPSRL", "length": 328 }, "evidence": [ { "id": "HGNC:14408", "url": "https://alliancegenome.org/gene/HGNC:14408#orthology", "database": "AGR" }, { "id": "HGNC:29446", "url": "https://alliancegenome.org/gene/HGNC:29446#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-1368", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1368#orthology", "database": "AGR" }, { "id": "MGI:1890404", "url": "https://alliancegenome.org/gene/MGI:1890404#orthology", "database": "AGR" }, { "id": "RGD:1563386", "url": "https://alliancegenome.org/gene/RGD:1563386#orthology", "database": "AGR" }, { "id": "FB:FBgn0026570", "url": "https://alliancegenome.org/gene/FB:FBgn0026570#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O18391-1", "protein_name": "Probable serine hydrolase", "gene_name": "kraken", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGQTRVAATTAAQSPAAELSPETNGQTEEPLQLLGEDSWEEFSIAVPWGTVEAKWWGSKERQPIIALHGWQDNCGSFDRLCPLLPADTSILAIDLPGHGKSSHYPMGMQYFIFWDGICLIRRIVRKYNWKNVTLLGHSLGGALTFMYAASFPTEVEKLINIDIAGPTVRGTQRMAEGTGRALDKFLDYETLPESKQPCYSYDEMIKLVLDAYDGSVDEPSVRVLMNRGMRHNPSKNGYLFARDLRLKVSLLGMFTAEQTLAYARQIRCRVLNIRGIPGMKFETPQVYADVIATLRENAAKVVYVEVPGTHHLHLVTPDRVAPHIIRFLKEA", "length": 331 }, "evidence": [ { "id": "HGNC:14408", "url": "https://alliancegenome.org/gene/HGNC:14408#orthology", "database": "AGR" }, { "id": "HGNC:29446", "url": "https://alliancegenome.org/gene/HGNC:29446#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-1368", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1368#orthology", "database": "AGR" }, { "id": "MGI:1890404", "url": "https://alliancegenome.org/gene/MGI:1890404#orthology", "database": "AGR" }, { "id": "RGD:1563386", "url": "https://alliancegenome.org/gene/RGD:1563386#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9EPB5-1", "protein_name": "Serine hydrolase-like protein", "gene_name": "Serhl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLHSELKLAVPWGHIALKVWGSQKNPPVLCLHGWLDNANSFDRLIPLLPQDFCYMAMDFGGHGLSSHYNPGLPYYQQNFVSEVRRVATAFKWNQFTLLGHSFGGCVGGTFACMFPEMVDKLILLDSTPFFLDSNEMENILTYRRRNIEHTLQVEASQKKSLRAVSPEEMLQGFLNNNSHLDKDCGELILQRGTTKVDAGLVLNRDRRISWPENSFDFVSKEMFVHSAKSLQASVLMIKALQGYYDVRRANDADKAPMHFMVDTLRSTLKERFQFVEVPGNHYIHMNKPQVVAGVVGPFLQGLQRMTSARL", "length": 311 }, "evidence": [ { "id": "HGNC:14408", "url": "https://alliancegenome.org/gene/HGNC:14408#orthology", "database": "AGR" }, { "id": "HGNC:29446", "url": "https://alliancegenome.org/gene/HGNC:29446#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-1368", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1368#orthology", "database": "AGR" }, { "id": "MGI:1890404", "url": "https://alliancegenome.org/gene/MGI:1890404#orthology", "database": "AGR" }, { "id": "RGD:1563386", "url": "https://alliancegenome.org/gene/RGD:1563386#orthology", "database": "AGR" }, { "id": "FB:FBgn0026570", "url": "https://alliancegenome.org/gene/FB:FBgn0026570#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H4I8-1", "protein_name": "Serine hydrolase-like protein 2", "gene_name": "SERHL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSENAAPGLISELKLAVPWGHIAAKAWGSLQGPPVLCLHGWLDNASSFDRLIPLLPQDFYYVAMDFGGHGLSSHYSPGVPYYLQTFVSEIRRVVAALKWNRFSILGHSFGGVVGGMFFCTFPEMVDKLILLDTPLFLLESDEMENLLTYKRRAIEHVLQVEASQEPSHVFSLKQLLQRLLKSNSHLSEECGELLLQRGTTKVATGLVLNRDQRLAWAENSIDFISRELCAHSIRKLQAHVLLIKAVHGYFDSRQNYSEKESLSFMIDTMKSTLKEQFQFVEVPGNHCVHMSEPQHVASIISSFLQCTHMLPAQL", "length": 314 }, "evidence": [ { "id": "HGNC:29446", "url": "https://alliancegenome.org/gene/HGNC:29446#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-1368", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1368#orthology", "database": "AGR" }, { "id": "MGI:1890404", "url": "https://alliancegenome.org/gene/MGI:1890404#orthology", "database": "AGR" }, { "id": "RGD:1563386", "url": "https://alliancegenome.org/gene/RGD:1563386#orthology", "database": "AGR" }, { "id": "FB:FBgn0026570", "url": "https://alliancegenome.org/gene/FB:FBgn0026570#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9NQF3-1", "protein_name": "Serine hydrolase-like protein", "gene_name": "SERHL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAENAAPGLISELKLAVPWGHIAAKAWGSLQGPPVLCLHGWLDNASSFDRLIPLLPQDFYYVAMDFGGHGLSSHYSPGVPYYLQTFVSEIRRVVAALKWNRFSILGHSFGGVVGGMFFCTFPEMVDKLILLDTPLFLLESDEMENLLTYKRRAIEHVLQVEASQEPSHVFSLKQLLQRQRTALTSSAGSCVRIPSGSCRPMSC", "length": 203 }, "evidence": [ { "id": "HGNC:14408", "url": "https://alliancegenome.org/gene/HGNC:14408#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-1368", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1368#orthology", "database": "AGR" }, { "id": "MGI:1890404", "url": "https://alliancegenome.org/gene/MGI:1890404#orthology", "database": "AGR" }, { "id": "RGD:1563386", "url": "https://alliancegenome.org/gene/RGD:1563386#orthology", "database": "AGR" }, { "id": "FB:FBgn0026570", "url": "https://alliancegenome.org/gene/FB:FBgn0026570#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VP50-1", "protein_name": "AB hydrolase-1 domain-containing protein", "gene_name": "Dmel\\CG7632", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKVSRGLFLLKQLPNVRNSSSGPTKPFKILNKHFDEISIPVPWGHISGKWYGPKHVRPIVGMHGWQDNAGTFDTLAPLLPSHLSFLSIDAPGHGLSSWLPPGTSYHSIDLVLITRRLMEEYNWDKISILAHSMSSINGFVFSALFPDKVDLFVGLDVLKPPVRSARGIVDSLTERIESALKLERRLKSGSEPPAYDWDQLVTRLHEGSNKSVSIDACKYLLQRNCKPSTHEPHKYYFSRDNRLKSSLFYTLHQEVPMEMARRIKCPHLFIKALQAPYYERKEYFDEVLAELQKNPLFEYHEVEGTHHVHLNEPEKVAPIINSFINRYRPL", "length": 330 }, "evidence": [ { "id": "HGNC:14408", "url": "https://alliancegenome.org/gene/HGNC:14408#orthology", "database": "AGR" }, { "id": "HGNC:29446", "url": "https://alliancegenome.org/gene/HGNC:29446#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-1368", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1368#orthology", "database": "AGR" }, { "id": "MGI:1890404", "url": "https://alliancegenome.org/gene/MGI:1890404#orthology", "database": "AGR" }, { "id": "RGD:1563386", "url": "https://alliancegenome.org/gene/RGD:1563386#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VP51-1", "protein_name": "AB hydrolase-1 domain-containing protein", "gene_name": "Dmel\\CG11309", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDTDDNSSGTITGSDLGQRYRHAGDLTGEAPTRPRANIWCSKKYFAEISITVPWGHISGKWYGPQNVQPILGLHGWQDNAGTFDRLMPLLSPDVAFLAIDLPGHGLSSRLPDGCYYNSVDNLYVIRLIMKQYKWEKVSLVGHSMSSIICFVFAAVFPDKVDMIIGIDALKPHQRPYPSVIRTMETRLDEFLREDERNRSKNEPPSYTYDELIERVYIGTFHSVNKEHCKHLMARNIGKSEKYPDKYFFCRDRRLKFYNYAIGSQELCVEMANRITCPYLFIKAAQSSYFEDKKYYDEVLDVLLKKPNFEYLEVNGSHHVHMNDPEAIIAPVNNFIQRFGPAAAAASRQKAKEAKESKL", "length": 358 }, "evidence": [ { "id": "HGNC:14408", "url": "https://alliancegenome.org/gene/HGNC:14408#orthology", "database": "AGR" }, { "id": "HGNC:29446", "url": "https://alliancegenome.org/gene/HGNC:29446#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-1368", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1368#orthology", "database": "AGR" }, { "id": "MGI:1890404", "url": "https://alliancegenome.org/gene/MGI:1890404#orthology", "database": "AGR" }, { "id": "RGD:1563386", "url": "https://alliancegenome.org/gene/RGD:1563386#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W045-1", "protein_name": "AB hydrolase-1 domain-containing protein", "gene_name": "BcDNA:SD08776", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MHKRLQYEEVMIPAPWGHIAGRWYGNRADRPILAIHGWLDNLGTFDRLIPLLPDYIGVLCIDLPGHGRSSRLPPGVPYNVYDYVFIIPRVMKEFGWSKVSLMGHSLGGVMSFMYAAMAPSTVDMIISLDVLLPRRIEDPSKLTKDIEGYLLEERRQADGTEHEPPSFTLSKLRETLARNSNNSVPQHLADHMLHRQVAKSNMYPEKVFFSRDGRVKFYHIFDIENGLALEMARRIEKKPYLVIKGSLSPFVGPRCNETMSILSHDNPNFEFYEVEGGKHHVHLHAAEECARYIVPFIRNHRPPRSSKL", "length": 308 }, "evidence": [ { "id": "HGNC:14408", "url": "https://alliancegenome.org/gene/HGNC:14408#orthology", "database": "AGR" }, { "id": "HGNC:29446", "url": "https://alliancegenome.org/gene/HGNC:29446#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-1368", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1368#orthology", "database": "AGR" }, { "id": "MGI:1890404", "url": "https://alliancegenome.org/gene/MGI:1890404#orthology", "database": "AGR" }, { "id": "RGD:1563386", "url": "https://alliancegenome.org/gene/RGD:1563386#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W048-1", "protein_name": "AB hydrolase-1 domain-containing protein", "gene_name": "Dmel\\CG15879", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSLSDFKEVRIPAPWGHISGRWYGNRTERPILAIHGWLDNLGTFDRLIPLLPDYIGVLCIDLPGHGRSAHIQPGMHYAVNDYVLIIPRVMKEYGWSKVSLMGHSLGGIISFVYTSLAPDTVDMVISLDILLPLSKDPKTVIKYLNHSLDKHLVEEERQVEGNLHEPPSYTLAQLTQVLAKGSDNSVTPEFAQHLLHRQVSKSQLYPDRFFFSRDGRVKYYSHLQMEPEFGEALVKRIRRIPCLIIKGSKSDFVEARTEKAVAILRQNNPHFEFYEVEGGTHHVHLHAAEECARYIVPFIRHHRPPALTSWSLSGKEEHLSAEEKRRQQERFFKRSTHAKSKL", "length": 342 }, "evidence": [ { "id": "HGNC:14408", "url": "https://alliancegenome.org/gene/HGNC:14408#orthology", "database": "AGR" }, { "id": "HGNC:29446", "url": "https://alliancegenome.org/gene/HGNC:29446#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-1368", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1368#orthology", "database": "AGR" }, { "id": "MGI:1890404", "url": "https://alliancegenome.org/gene/MGI:1890404#orthology", "database": "AGR" }, { "id": "RGD:1563386", "url": "https://alliancegenome.org/gene/RGD:1563386#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "Q9W047", "url": "https://www.uniprot.org/uniprotkb/Q9W047" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 277, "end_pos": 279, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9W047", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W047" }, { "id": "PF00561", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00561" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AB hydrolase-1", "eco_id": "ECO_0000259", "start_pos": 33, "end_pos": 284, "start_aa": "Pro", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 277, "end_pos": 279 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9W077-1", "uniprot_ac": "Q9W077", "uniprot_id": "Q9W077_DROME", "mass": { "chemical_mass": 18684.0, "monoisotopic_mass": 18684.0 }, "refseq": { "ac": "NP_001261293", "name": "cuticular protein 62Bc, isoform B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261293" }, "gene_names": [ { "name": "Cpr62Bc", "type": "recommended", "evidence": [ { "id": "Q9W077", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W077" } ] }, { "name": "CG1919", "type": "synonym", "evidence": [ { "id": "NP_001261293", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261293" }, { "id": "Q9W077", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W077" } ] }, { "name": "Cpr62Bc", "type": "synonym", "evidence": [ { "id": "NP_001261293", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261293" } ] }, { "name": "DmelCpr62Bc", "type": "synonym", "evidence": [ { "id": "NP_001261293", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261293" }, { "id": "Q9W077", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W077" } ] }, { "name": "Dmel\\CG1919", "type": "synonym", "evidence": [ { "id": "NP_001261293", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261293" }, { "id": "Q9W077", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W077" } ] }, { "name": "Dmel_CG1919", "type": "synonym", "evidence": [ { "id": "Q9W077", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W077" } ] } ], "protein_names": [ { "name": "CG1919-PB", "type": "synonym", "evidence": [ { "id": "NP_001261293", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261293" } ] }, { "name": "Cpr62Bc-PB", "type": "synonym", "evidence": [ { "id": "NP_001261293", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261293" } ] }, { "name": "Cuticular protein 62Bc, isoform A", "type": "synonym", "evidence": [ { "id": "Q9W077", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W077/entry#names_and_taxonomy" } ] }, { "name": "Cuticular protein 62Bc, isoform B", "type": "synonym", "evidence": [ { "id": "Q9W077", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W077/entry#names_and_taxonomy" } ] }, { "name": "cuticular protein 62Bc, isoform B", "type": "synonym", "evidence": [ { "id": "NP_001261293", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261293" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W077", "url": "https://www.uniprot.org/uniprotkb/Q9W077" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Cpr62Bc", "url": "https://www.uniprot.org/uniprotkb/Q9W077", "locus": { "chromosome": "3L", "start_pos": 1840281, "end_pos": 1842084, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0035281", "url": "https://www.ensemblgenomes.org/id/FBgn0035281" } ] } } ], "crossref": [ { "id": "FB:FBgn0035281", "url": "https://alliancegenome.org/gene/FB:FBgn0035281", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0035281", "url": "https://bgee.org/?page=gene&gene_id=FBgn0035281", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0035281", "url": "https://flybase.org/reports/FBgn0035281", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "38241", "url": "https://www.ncbi.nlm.nih.gov/gene/38241", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000618", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000618", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031311", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031311", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051217", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051217", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG1919", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG1919", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HAHVSHY", "url": "https://omabrowser.org/oma/group/HAHVSHY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W077", "url": "https://www.orthodb.org/?gene=Q9W077", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12236", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12236", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12236:SF80", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12236:SF80", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00379", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00379", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001261293", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261293", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W077", "url": "https://www.uniprot.org/uniprotkb/Q9W077", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W077-1", "url": "https://www.uniprot.org/uniprotkb/Q9W077-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFFKSLICLAVLSAASAGVLHGHGAGLYAAAPAIYAGHGHHDEGIDYHAYPKYHYNYGVADSHTGDVKSQHEVRDGDVVKGSYSLVEPDGSVRTVEYTADDHNGFNAVVHKTGPTVHHAAPAVVAHAAPAVVHAAPAYAPAIAHHVAAAPAVPYAGSLAHQVPAYGYATHNAHAHVAHY", "length": 180, "header": "tr|Q9W077-1|Q9W077_DROME Isoform 1 of Cuticular protein 62Bc, isoform B OS=Drosophila melanogaster OX=7227 GN=Cpr62Bc PE=1 SV=1 CANONICAL=Q9W077-1" }, "isoforms": [ { "isoform_ac": "Q9W077-1", "url": "https://www.uniprot.org/uniprotkb/Q9W077/entry#Q9W077-1", "sequence": { "sequence": "MAFFKSLICLAVLSAASAGVLHGHGAGLYAAAPAIYAGHGHHDEGIDYHAYPKYHYNYGVADSHTGDVKSQHEVRDGDVVKGSYSLVEPDGSVRTVEYTADDHNGFNAVVHKTGPTVHHAAPAVVAHAAPAVVHAAPAYAPAIAHHVAAAPAVPYAGSLAHQVPAYGYATHNAHAHVAHY", "length": 180, "header": "tr|Q9W077-1|Q9W077_DROME Isoform 1 of Cuticular protein 62Bc, isoform B OS=Drosophila melanogaster OX=7227 GN=Cpr62Bc PE=1 SV=1 CANONICAL=Q9W077-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan 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"authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W077", "url": "https://www.uniprot.org/uniprotkb/Q9W077" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W077", "url": "https://www.uniprot.org/uniprotkb/Q9W077" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable 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Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W077", "url": "https://www.uniprot.org/uniprotkb/Q9W077" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W077", "url": "https://www.uniprot.org/uniprotkb/Q9W077" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi 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"MDVEDSVASGAASACKRQKRNTDSQNDGEPEDAAQIGEENTVAESQPLINFDTIVTHNNNGESDMEGKENQLQDESEQSEEHLANKVGPEELPEIEQAGSSNLAHQLSPEAASTVLASDEPDASTGVIEPSDSEDYPPTSPTPIEASEAVSSPRFNPRNIPPTRSYRRISIELVGSYSDTSDSEEHELEEGTEHAEEYSDDAPEPHIAESADDSSSNDDMGPYSLSSEDETTTEVENLQDEVEFNEDINPADREKVDYAVNQVMCKCKPKYTWNYDQELLQREHNIINRIDWRGGHTSASSFGQGYYGSRQVVEQMTLLSSLNVHHGCVNSLNFNRAGDLICSGSDDLTIVVWDWAKEKQLHRFRSGHNMNIFQTKFIDSAGCLDIVSSSRDGQVRRSVIPPSGGVIKPIRLYTHSESVHKIIVVPHSRHELMSAGEDAAVKHFDLRASNAATTMMRCVYNDENERGRVRLFSIAHHPYAPEFCVSGSDDILRVYDKRNLAKAIHQMAPRNLLEAQITQITCAVYNHSGSEILASYSDAGIYLFDSRNYNRGDYLHCYKGHINSRTIKGVNFFGPRSEYIVSGSDCGNIFFWDKNTEAIINYMKGDHVGVVNCLEPHPWMPVLATSGLEHDVKIWTPQGPERKLPEDLLKQTLQRNFRCNIVESIDLDINNFQYFIRGFLQGSGASHLRQRHTSSLGHQMRDNSSSRSNGSNASNPTSHRRNSNSSDDTNDEGADADAALDTLHCRTQ", "length": 748, "header": "tr|Q9W091-1|Q9W091_DROME Isoform 1 of DDB1- and CUL4-associated factor 8 OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG8001 PE=1 SV=1 CANONICAL=Q9W091-1" }, "isoforms": [ { "isoform_ac": "Q9W091-1", "url": "https://www.uniprot.org/uniprotkb/Q9W091/entry#Q9W091-1", "sequence": { "sequence": "MDVEDSVASGAASACKRQKRNTDSQNDGEPEDAAQIGEENTVAESQPLINFDTIVTHNNNGESDMEGKENQLQDESEQSEEHLANKVGPEELPEIEQAGSSNLAHQLSPEAASTVLASDEPDASTGVIEPSDSEDYPPTSPTPIEASEAVSSPRFNPRNIPPTRSYRRISIELVGSYSDTSDSEEHELEEGTEHAEEYSDDAPEPHIAESADDSSSNDDMGPYSLSSEDETTTEVENLQDEVEFNEDINPADREKVDYAVNQVMCKCKPKYTWNYDQELLQREHNIINRIDWRGGHTSASSFGQGYYGSRQVVEQMTLLSSLNVHHGCVNSLNFNRAGDLICSGSDDLTIVVWDWAKEKQLHRFRSGHNMNIFQTKFIDSAGCLDIVSSSRDGQVRRSVIPPSGGVIKPIRLYTHSESVHKIIVVPHSRHELMSAGEDAAVKHFDLRASNAATTMMRCVYNDENERGRVRLFSIAHHPYAPEFCVSGSDDILRVYDKRNLAKAIHQMAPRNLLEAQITQITCAVYNHSGSEILASYSDAGIYLFDSRNYNRGDYLHCYKGHINSRTIKGVNFFGPRSEYIVSGSDCGNIFFWDKNTEAIINYMKGDHVGVVNCLEPHPWMPVLATSGLEHDVKIWTPQGPERKLPEDLLKQTLQRNFRCNIVESIDLDINNFQYFIRGFLQGSGASHLRQRHTSSLGHQMRDNSSSRSNGSNASNPTSHRRNSNSSDDTNDEGADADAALDTLHCRTQ", "length": 748, "header": "tr|Q9W091-1|Q9W091_DROME Isoform 1 of DDB1- and CUL4-associated factor 8 OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG8001 PE=1 SV=1 CANONICAL=Q9W091-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 142, "start_aa": "Thr", "end_pos": 142, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr142", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W091", "url": "https://www.uniprot.org/uniprotkb/Q9W091" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W091", "url": "https://www.uniprot.org/uniprotkb/Q9W091" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W091", "url": "https://www.uniprot.org/uniprotkb/Q9W091" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W091", "url": "https://www.uniprot.org/uniprotkb/Q9W091" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W091", "url": "https://www.uniprot.org/uniprotkb/Q9W091" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W091", "url": "https://www.uniprot.org/uniprotkb/Q9W091" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W091", "url": "https://www.uniprot.org/uniprotkb/Q9W091" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W091", "url": "https://www.uniprot.org/uniprotkb/Q9W091" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W091", "url": "https://www.uniprot.org/uniprotkb/Q9W091" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W091", "url": "https://www.uniprot.org/uniprotkb/Q9W091" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W091", "url": "https://www.uniprot.org/uniprotkb/Q9W091" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "R-DME-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8951664", "resource": "Reactome", "description": "Neddylation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LJS1-1", "protein_name": "DDB1 and CUL4 associated factor 8-like 1", "gene_name": "Dcaf8l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSQGSYAKVAESFENISEHSCLSETSGALVDTETISDIKMKGPEVSLAPSSNVTETEESSVSSPQNTDENSGDGYQGYEGDDDDDDDDSNLPSFEDSDNFISSTECSSSPQELEEGEIVEEQSVGRLFHHYELEAGEVVEAQGVQNLFCSYELEEGEVLEAPRVQSMLCHYELEAGEVVEAQEVQGLFCHYELEEGEVVEAQGVQSLVQYHELEEGEVVEAQGVQSLVQYCELEEGEVVVAQGVQSLVQHHELEEGEVVEHEIGSLLLRRHHVLDACEIVEEQGLESPFHHRVLGQGVVGNDQDEVSEVYEQNSVERSEQYDIEDSSIDEWMALETSPLLKPRWNVLNALRDRQLGSSGRFVYEACGARLFVQRFSLEYVFEGHAGCVNTVHFNQRGTLLASGSDDLKVIVWDWLHQRPLLNFDSGHKNNVLQAKFLPNCNDAILAMCGRDGQVRVAHLSAMAGTHMTKRLVKHGGASHRLGLEPDSPFRFLSSGEDAVVFSIDLRQAQPASKLMVTKDGDKKVGLYTVFVNPANVYQFAVGGQDQFVRIYDQRKIDENVNNGVLKKFCPHHLISCEYPAYITSLMYSYDGTEVLASYNDEDIYIFNSSDSDGAQYAKRYKGHRNNATVKGVYFYGPRSEFVMSGSDCGHIFIWEKSSCQIVQFLEADEGGTINCIDPHPYMPVLASSGLDHEVKIWSPIAETSSKLTGLKNVIKINKLKRDNFTLHHTSLFDNHMLWFLMSHLTQSNYQRNLRGIRIEVGGGDFSDSSSSSDEEENQDSQCQTS", "length": 786 }, "evidence": [ { "id": "HGNC:31810", "url": "https://alliancegenome.org/gene/HGNC:31810#orthology", "database": "AGR" }, { "id": "HGNC:31811", "url": "https://alliancegenome.org/gene/HGNC:31811#orthology", "database": "AGR" }, { "id": "RGD:1584985", "url": "https://alliancegenome.org/gene/RGD:1584985#orthology", "database": "AGR" }, { "id": "MGI:101758", "url": "https://alliancegenome.org/gene/MGI:101758#orthology", "database": "AGR" }, { "id": "FB:FBgn0035268", "url": "https://alliancegenome.org/gene/FB:FBgn0035268#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A2AHY8-1", "protein_name": "DDB1 and CUL4 associated factor 8 like", "gene_name": "Dcaf8l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSHESYTNAAETPENISILSCLGETSGALVDTKTISDIKTMDPEVSLTPSSDVTGTEDSSVLSPQSTDVNSVDSYQGYEGDDDDEEDDEDDKDGDSNLPSLEDSDNFISCLENSYIPQNVEKREVVEEQSLGRRFHPYELEAGEVVEGQGGGSLFYPYELEAGEVVEAQNVQNLFHRYELEEGEVVEAQVVQSMFPYYELEAGEVVEAEEVQGFFQRYELEAREVIGAQGGQGLSRHYGLEGGEVVEATAVRRLIQHHELEEGEDVDDQEESSEMHEETSEDSSEQYDIEDDSLIDEWIALETSPLPRPRWNVLSALRDRQLGSSGRFVYEACGARLFVQRFSLEHVFEGHSGCVNTVHFNQHGTLLASGSDDLKVIVWDWLKKRSVLNFDSGHKNNILQAKFLPNCNDAILAMCGRDGQVRVAQLSAVAGTHMTKRLVKHGGASHRLGLEPDSPFRFLTSGEDAVVFNIDLRQAHPASKLLVIKDGDKKVGLYTVFVNPANVYQFAVGGQDQFMRIYDQRKIDENVNNGVLKKFCPHHLLSSDYPAHITSLMYSYDGTEILASYNDEDIYIFNSSDSDGAQYAKRYKGHRNNSTVKGVYFYGPRSEFVMSGSDCGHIFIWEKSSCQIVQFLEADEGGTINCIDSHPYLPVLASSGLDHEVKIWSPIAEPSKKLAGLKNVIKINKLKRDNFTLRHTSLFNNSMLCFLMSHVTQSNYGRSWRGIRINAGGGDFSDSSSSSEETNQES", "length": 747 }, "evidence": [ { "id": "HGNC:31810", "url": "https://alliancegenome.org/gene/HGNC:31810#orthology", "database": "AGR" }, { "id": "HGNC:31811", "url": "https://alliancegenome.org/gene/HGNC:31811#orthology", "database": "AGR" }, { "id": "RGD:1584985", "url": "https://alliancegenome.org/gene/RGD:1584985#orthology", "database": "AGR" }, { "id": "MGI:101758", "url": "https://alliancegenome.org/gene/MGI:101758#orthology", "database": "AGR" }, { "id": "FB:FBgn0035268", "url": "https://alliancegenome.org/gene/FB:FBgn0035268#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A6NGE4-1", "protein_name": "DDB1- and CUL4-associated factor 8-like protein 1", "gene_name": "DCAF8L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSHQEGSTGGLPDLVTESLFSSPEEQSGVAAVTAASSDIEMAATEPSTGDGGDTRDGGFLNDASTENQNTDSESSSEDVELESMGEGLFGYPLVGEETEREEEEEEMEEEGEEEEQPRMCPRCGGTNHDQCLLDEDQALEEWISSETSALPRSRWQVLTALRQRQLGSSARFVYEACGARTFVQRFRLQYLLGSHAGSVSTIHFNQRGTRLASSGDDLRVIVWDWVRQKPVLNFESGHDINVIQAKFFPNCGDSTLAMCGHDGQVRVAELINASYCENTKRVAKHRGPAHELALEPDSPYKFLTSGEDAVVFTIDLRQDRPASKVVVTRENDKKVGLYTISMNPANIYQFAVGGHDQFVRIYDQRRIDKKENNGVLKKFTPHHLVYCDFPTNITCVVYSHDGTELLASYNDEDIYLFNSSLSDGAQYVKRYKGHRNNDTIKCVNFYGPRSEFVVSGSDCGHVFFWEKSSSQIIQFMEGDRGDIVNCLEPHPYLPVLATSGLDQHVRIWTPTAKTATELTGLKDVIKKNKQERDEDNLNYTDSFDNRMLRFFVRHLLQRAHQPGWRDHGAEFPDEEELDESSSTSDTSEEEGQDRVQCIPS", "length": 600 }, "evidence": [ { "id": "HGNC:31810", "url": "https://alliancegenome.org/gene/HGNC:31810#orthology", "database": "AGR" }, { "id": "RGD:1584985", "url": "https://alliancegenome.org/gene/RGD:1584985#orthology", "database": "AGR" }, { "id": "MGI:101758", "url": "https://alliancegenome.org/gene/MGI:101758#orthology", "database": "AGR" }, { "id": "FB:FBgn0035268", "url": 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] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9W0B6-1", "uniprot_ac": "Q9W0B6", "uniprot_id": "Q9W0B6_DROME", "mass": { "chemical_mass": 51526.0, "monoisotopic_mass": 51526.0 }, "refseq": { "ac": "NP_647638", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647638" }, "gene_names": [ { "name": "Dmel\\CG17249", "type": "recommended", "evidence": [ { "id": "Q9W0B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W0B6" } ] }, { "name": "CG17249", "type": "synonym", "evidence": [ { "id": "NP_647638", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647638" }, { "id": "Q9W0B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W0B6" } ] }, { "name": "Dmel\\CG17249", "type": "synonym", "evidence": [ { "id": "NP_647638", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_647638" } ] }, { "name": "Dmel_CG17249", "type": "synonym", 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"MSLVAYAASSDEDSENEEENSVPQVEVIKPQAKPSTPSEAYLARESTSGHISDEDDDYVPQEVSLQELKPPNGRLLLALPKPKVTAPAKDLENEDVDNQVTSAFANLPMPRTAAKGKAIVEEKDDEFLHKKALPVEIEKPPPPPVKGKVKISIPSLRDFSDVDQEKADRAKNKVDKPNVPKGSGLLSLLPQAKSERNFSKNSSSAVAYPSASTTLASSLSNNPAQPRAAPAFVPDTVKQRRAAHNTEGVDGPKAGHKKNPETKDALKSTKSKPISKPTSLVNASDSEDDDEDGTGDFFSLNSEQKLPEVSSNEISALVAKRAAKMVEASSKYLEEVAEKEAAEAEAARLQEEQSQIAQKRYHEQQLNAEAMDALVGKNAKRRRKEAKEMQVIDISGSQVLPDREEWMRSALASSTTFQPTGVLTDEEPVAGTRRKHQITYLAHKAKANEAELQAMWSANRQTRRATQSKYGF", "length": 472, "header": "tr|Q9W0B6-1|Q9W0B6_DROME Isoform 1 of Proline-rich protein PRCC OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG17249 PE=1 SV=1 CANONICAL=Q9W0B6-1" }, "isoforms": [ { "isoform_ac": "Q9W0B6-1", "url": "https://www.uniprot.org/uniprotkb/Q9W0B6/entry#Q9W0B6-1", "sequence": { "sequence": "MSLVAYAASSDEDSENEEENSVPQVEVIKPQAKPSTPSEAYLARESTSGHISDEDDDYVPQEVSLQELKPPNGRLLLALPKPKVTAPAKDLENEDVDNQVTSAFANLPMPRTAAKGKAIVEEKDDEFLHKKALPVEIEKPPPPPVKGKVKISIPSLRDFSDVDQEKADRAKNKVDKPNVPKGSGLLSLLPQAKSERNFSKNSSSAVAYPSASTTLASSLSNNPAQPRAAPAFVPDTVKQRRAAHNTEGVDGPKAGHKKNPETKDALKSTKSKPISKPTSLVNASDSEDDDEDGTGDFFSLNSEQKLPEVSSNEISALVAKRAAKMVEASSKYLEEVAEKEAAEAEAARLQEEQSQIAQKRYHEQQLNAEAMDALVGKNAKRRRKEAKEMQVIDISGSQVLPDREEWMRSALASSTTFQPTGVLTDEEPVAGTRRKHQITYLAHKAKANEAELQAMWSANRQTRRATQSKYGF", "length": 472, "header": "tr|Q9W0B6-1|Q9W0B6_DROME Isoform 1 of Proline-rich protein PRCC OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG17249 PE=1 SV=1 CANONICAL=Q9W0B6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W0B6", "url": "https://www.uniprot.org/uniprotkb/Q9W0B6" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W0B6", "url": "https://www.uniprot.org/uniprotkb/Q9W0B6" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W0B6", "url": "https://www.uniprot.org/uniprotkb/Q9W0B6" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W0B6", "url": "https://www.uniprot.org/uniprotkb/Q9W0B6" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W0B6", "url": "https://www.uniprot.org/uniprotkb/Q9W0B6" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W0B6", "url": "https://www.uniprot.org/uniprotkb/Q9W0B6" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W0B6", "url": "https://www.uniprot.org/uniprotkb/Q9W0B6" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W0B6", "url": "https://www.uniprot.org/uniprotkb/Q9W0B6" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W0B6", "url": "https://www.uniprot.org/uniprotkb/Q9W0B6" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W0B6", "url": "https://www.uniprot.org/uniprotkb/Q9W0B6" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W0B6", "url": "https://www.uniprot.org/uniprotkb/Q9W0B6" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], 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Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W0E1", "url": "https://www.uniprot.org/uniprotkb/Q9W0E1" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W0E1", "url": "https://www.uniprot.org/uniprotkb/Q9W0E1" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W0E1", "url": "https://www.uniprot.org/uniprotkb/Q9W0E1" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W0E1", "url": "https://www.uniprot.org/uniprotkb/Q9W0E1" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W0E1", "url": "https://www.uniprot.org/uniprotkb/Q9W0E1" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W0E1", "url": "https://www.uniprot.org/uniprotkb/Q9W0E1" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W0E1", "url": "https://www.uniprot.org/uniprotkb/Q9W0E1" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W0E1", "url": "https://www.uniprot.org/uniprotkb/Q9W0E1" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W0E1", "url": "https://www.uniprot.org/uniprotkb/Q9W0E1" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W0E1", "url": "https://www.uniprot.org/uniprotkb/Q9W0E1" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W0E1", "url": "https://www.uniprot.org/uniprotkb/Q9W0E1" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG7852", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG7852", "resource": "KEGG Pathway" }, { "id": "R-DME-8876198", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8876198", "resource": "Reactome", "description": "RAB GEFs exchange GTP for GDP on RABs" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1L1RT22-1", "protein_name": "DENN domain containing 5A", "gene_name": "DENND5A", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSGGSGGGSSAPGRFADYFVICGLDTETGLEPDELSALCQYIQASKTRDGASRFISSATEGENFDQTPLRRTFKSKVLARYPENVEWNPFDQDAVGMLCMPKGLAFKTQADSREPQFHSFIITREDGSRTFGFSLTFFEEVTSKQICSAMQTLYHMHNAEYDILHTPPTNDKDSCSSTGDCNGTSISKLQRFNSYDISRDTLYVSKCICLITPMSFMKACKKVLEQLHQAVTSPQPPPLPLESYIYNILYEVPLPPAGRSLKFSGVYGPIICQRPSTNELPLFDFPVKEVFELLGVENVVQLFTCALLEFQILLYSQHYQRLMTVAETITALMFPFQWQHVYVPILPASLLHFLDAPVPYLMGLHSNGLDDRSKLELPQEANLCFVDVDNHFIELPEDLPQFPNKLEFVQEISEILTAFGIPPEGNLHYSESASKMKSLRACDLVSDKRNGNVAGSPLNSYELLKENETIARLQALVKRTGVSLEKLEVREETSSKKDLKIQCDEEEFKIYQLNIQIREIFANRFTQMFADYEVFVIQPSQDKESWFTNREQMQNFDKASFLSDQPEPYLPFLSRFLETQMFASFIDNKIMCHDEDDKDPILRVFDSRVDKIRLLNVRTPTLRTSMYQKCTTIDEAEKSIELRLAKIDHTAVHPHLLDMKIGQGKYELGFFPKLQSDVLSTGPASNKWTKRNAPAQWRRKDRQKQHTEHLRLDNDQREKYIQEARNLGSTIRQPKLSNLSPSVIAQTNWKFVEGLLKECRNKTKRMLVEKMGREAVELGHGEVNITGVEENTLIASLCDLLERIWSHGLQIKQDRSCTAFVLEDRASVYSASTQIWAFQTTRRPTLHKGKSALWSHLLHYLENRQRKTTSGSFSTSGILLDSERRKSDTSPGMSPLRISLVQDMRHIQNISEIKTDVGKARAWVRLSMEKKLLSRHLKQLLSDHELTKKLYKRYAFLRCDDEKEQFLYHLLSFNAVDYFCFTNVFTTILIPYHILIVPSKKLGGSMFTANPWICISGELGETGVLQIPRNILEMTFECQNLGKLTTVQIGHDNSGLYAKWLVEYVMVRNEITGHTYKFPCGRWLGKGMDDGSLERILVGELLTSNTEADERQCRTPPLQQSPSMIRRLVTISPNNKPKLNTGQIQEAIGEAVNGIVKHFHKPEKERGSLTLLLCGESGLVSALEQVFQHGFKSPRLFKNVFIWDFLEKAQTYYETLEQNEMVPEENWQTRARNFCRFITAINNTPRNIGKDGKFQMLVCLGARDHLLHHWIALLADCPITAQMYEDIALIKDHTLVNSLIRVLQTLQEFNITLEASLVKGIDI", "length": 1323 }, "evidence": [ { "id": "Q9W0E1", "url": "https://omabrowser.org/oma/group/Q9W0E1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8I5ZYN4-1", "protein_name": "DENN domain containing 5B", "gene_name": "Dennd5b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGSGAAPGPGSGSSPAACRFAHYFVLCGIDADSGLEPDELAGENFDQSPLRRTFKSKVLAHYPQNIEWNPFDQDAVNMLCMPKGLSFRTQADNKDPQFHSFIITREDGSRTYGFVLTFYEEVTSKQICTAMQTLYQMHNAEQYSSVYASSSCSMDSLASSIDEGDATSLLKLQRYNSYDINRDTLYVSKSICLITPLPFMQACRKFLLQLHKAVTSQQPPPLPLESYIHNILYEVPLPPPGRSLKFYGVYEPVICQRPGPNELPLSDYPLREACELLGLENLVQVFTCVLLEMQILLYSQDYQRLMTVAEGITTLLFPFQWQHVYVPILPASLLHFLDAPVPYLMGLQSKEGTDRSKLELPQEANLCFVDIDNHFIELPEEFPQFPNKVDFIQELSEVLLQFGIPPEGSLHCSESATKLKNMVLKDLANDKKNGNVPTNNVSVYELLKGSETIARLQALAKRTGVTVGKIDFPASLSEKEKDLKLQCEEADLRDSQLNVQLREVFANRFTQMFADYEAFVIQTAQDMESWLTSREQMQNFDKASFLSDQPEPYLPFLSRFIETQMFATFIDNKIMSQWEEKDPLLRVFDSRIEKMRLYNVRAPTLRTSIYQKCSSLKEAAQSIEQRLMKMDHTAIHPHLLDMKIGQGKYEQGFFPKLQSDVLATGPANNNRWVSRSTTAQRRKERLRQNAEHIGLDSDLREPSGELLVCQNSMAFWEWDQGPTPPARLPKKSFSECCLKYMQEARSLGKNLRQPKLSDLSPAVIAQTNWKFVEGLLKECRMKTKRMLVEKMGHEAVELGHGEANITGLEENTLIASLCDLLERIWSHGLLVKQGKSALWSHLIQFQDREEKQEHLTDSPVALGPERRKSDSGVMLPTLRVSLIQDMRHVQNMTEIKTDVGRARAWIRLSLEKKLLSQHLKQLLSNQPLTKKLYKRYAFLRCEEEREQFLYHLLSLNAVDYFCFTSVFTTIMIPYRSVIIPIKKLSNAIITSNPWICVSGELGDTGVMQIPKNLLEMTFECQNLGKLTTVQIGHDNSGLLAKWLVDCVMVRNEITGHTYRFPCGRWLGKGVDDGSLERILIGELMTSASDEDLGKQCRTPPQQKSPTTTRRLSITSLTGKPAKPNAGQIQEGIGEAVNNIVKHFHKPEKERGSLTVLLCGENGLVAALEQVFHHGFKSARIFHKNVFIWDFVEKAVAYFESTDQILDNEDDMLIQKPSCKTFCHYVNAVNTAPRNIGKDGKFQILVCLGTRDHLLPQWIPLLAECPAITRMYEENALLRDHMTVNSLIRILQTIQDFTIVLEGSLIKGVDV", "length": 1311 }, "evidence": [ { "id": "HGNC:28338", "url": "https://alliancegenome.org/gene/HGNC:28338#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-2248", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-2248#orthology", "database": "AGR" }, { "id": "MGI:2444273", "url": "https://alliancegenome.org/gene/MGI:2444273#orthology", "database": "AGR" }, { "id": "RGD:2318606", "url": "https://alliancegenome.org/gene/RGD:2318606#orthology", "database": "AGR" }, { "id": "FB:FBgn0035229", "url": "https://alliancegenome.org/gene/FB:FBgn0035229#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M3B1L1-1", "protein_name": "DENN domain-containing protein 5A isoform X1", "gene_name": "dennd5a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSTGFSSSSCRFADYFVICGLDTESGLEPDELSALCQYIQATKFTDGARGKLASANEGENFEQSPLRRTFKSKVLAHYPDNVEWNPFDQDAVGMLCMPKGLSFRTQTDTREPQFHSFIITREDGSRTYGFALTFFEEVTSKQICSAMQTLYHMHNAEQYDILHTPPTPRSPEDPRPTTQQLHASPALSRLQRFNSYDISRDTLYVSKCICLITPMAFAHACRKVLEQLHQAVTSPQPPPLPLESYVYNVLYEVPLPPAGRSLKFSGVYRPVICQRPSTAELPLFDFPLQEVFELLGLENILQLFTCALLEIQILLYSQHYQRLMTVAESITALMFPFQWQHVYVPILPASLLHFLDAPVPYLMGLHSNGQDDRTKLELPQEANLCFVDIDNHFIELPEDLPQFPNKLEFIQEISEVLLAFGLSPEANPQCSEGQSKIRGFRCGDMASDKRNGNLAGSPLNSFLLRENQTIARLQALVKRTGVSLEKLDVKDDASTNKDTKVQCEEEEMKMHQLNIRVREVFANRFSQMFSDYEVFVIQPSQDKESWFSNRDQMQNFDKASFLSDQPEPYLPFLSRFLETQMFASFIDSKILCHDDEDKEHTLRVFDSRVDKIRMINVRTPTLRTSMYQKCTNIDEAEKAIEVRLCKIDHTALHPHLLDMKIGQGRYEPGFFPRLQSDVLSTGPTSNKWAKRSAPAQWRRKDRQKQHAEHLYLDNDQREHVECLFSELQLLLALDYYWFSQSFRPCLKSVKVDVKYIQEARNLGTTLRQPKLSNLSPSVIAQTNWKFVEGLLKECRNKTKRMLVEKMGREAVELGHGEVSITGVEENTLIASLCDLLERIWSHGLQVKQGKSALWSHLLHYQESKEKRDATPAGLGPPGIIHDTERRKSDASCAMPPLKVSLIQDMRHIQNISEIKTDVGKARAWVRLSMEKKLLSRHLKQLLSDHELTKKLYKRYAFLRCDDEKEQFLYHLLSFNAVDYFCFTNVFTTIMIPYHVVIIPSKKLGGSMFTANPWVCVSGELAETGVLQVPKNTLEITFECQNLGKLTTVQMGHDNSGLYAKWLVECVMVRNGITGHTYKFPCGRWLGKGVDDGSLERILVGELVTNMESDERMCRTPPMQQSPGMMRRFVTISPNSKPKLNTGQIQESVGEAINGIVKHFHKPEKERGSLTLLLCGEYGLVWALEQVFQHGFKSPRLFKNVFIWDFLEKAQVYFESAERSQMTQDENWQMRVRHFCHFMRAINSTPRNIGKDGKFQMLVCLGARDHLLHHWIALLAECPITAQMYEDVALLKDHSLVNSLIRVLQTLQEFNITLEASLVKGIGI", "length": 1323 }, "evidence": [ { "id": "HGNC:19344", "url": "https://alliancegenome.org/gene/HGNC:19344#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-071211-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-071211-1#orthology", "database": "AGR" }, { "id": "MGI:1201681", "url": "https://alliancegenome.org/gene/MGI:1201681#orthology", "database": "AGR" }, { "id": "RGD:1306759", "url": "https://alliancegenome.org/gene/RGD:1306759#orthology", "database": "AGR" }, { "id": "FB:FBgn0035229", "url": "https://alliancegenome.org/gene/FB:FBgn0035229#orthology", "database": "AGR" }, { "id": "Q9W0E1", "url": "https://omabrowser.org/oma/group/Q9W0E1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AAA9SAM7-1", "protein_name": "DENN domain containing 5A", "gene_name": "DENND5A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSGGGGGGGGGGSAPSRFADYFVICGLDTETGLEPDELSALCQYIQASKARDGASSFISSTTEGENFEQTPLRRTFKSKVLARYPENVDWNPFDQDAVGMLCMPKGLAFKTQADPREPQFHAFIITREDGSRTFGFALTFYEEVTSKQICSAMQTLYHMHNAEYDVLHAPLADSRDLSGMEDGDGTPGTKLQRFNSYDISRDTLYVSKCICLITPMSFMKACRSVLEQLHQAVTSPQPPPLPLESYIYNVLYEVPLPPPGRSLKFSGVYGPIVCQRPSTNELPLFDFPVKEVFELLGVENVFQLFTCALLEFQILLYSQHYQRLMTVAETITALMFPFQWQHVYVPILPASLLHFLDAPVPYLMGLHSNGLDDRSKLELPQEANLCFVDIDNHFIELPEDLPQFPNKLEFVQEVSEILMAFGIPPEGSLHCSESASKLKRLRASELVSDKRNGNIAGSPLHSYEFLKENETIARLQALVKRTGVSLEKLEVREDPSSNKDLKVQCDEEELRIYQLNIQIREVFANRFTQMFADYEVFVIQPSQDKESWFTNREQMQNFDKASFLSDQPEPYLPFLSRFLETQMFASFIDNKIMCHDDDDKDPVLRVFDSRVDKIRLLNVRTPTLRTSMYQKCTTVDEAKKAIELRLAKIDHTAVHPHLLDMKIGQGKYEPGFFPKLQSDVLSTGPASNKWTKRNAPAQWRRKDRQKQHTEHLRLDNDQREKYIQEARNMGSTIRQPKLSNLSPSVIAQTNWKFVEGLLKECRNKTKRMLVEKMGREAVELGHGEVNITGVEENTLIASLCDLLERIWSHGLQVKQGKSALWSHLLHYQENRQRKLTSGSLSTSGIFLDSERRKSDASSVMSPLKISLIQDMRHIQNIGEIKTDVGKARAWVRLSMEKKLLSRHLKQLLSDHELTKKLYKRYAFLRCDDEKEQFLYHLLSFNAVDYFCFTNVFTTILIPYHILIVPSKKLGGSMFTANPWICISGELGETQILQIPRNLLEMTFECQNLGKLTTVQIGHDNSGLYAKWLVEYVMVRNEITGHTYKFPCGRWLGKGMDDGSLERVLVGELLTSQPEVDERPCRTPPLQQSPSVIRRLVTISPNNRPKLNTGQIQESIGEAVNGIVKHFHKPEKERGSLTLLLCGECGLVSALEQAFQHGFKSPRLFKNVFIWDFLEKAQTYYETLEQNELVPEENWHMRARNFCRFVTAINNNPRNIGKDGKFQMLVCLGARVVMKVSLTKGPAHARCYLDHLLHHWIALLADCPITAHMYEDVALIKDHTLVNSLIRVLQTLQEFNITLETSLVKGIDI", "length": 1308 }, "evidence": [ { "id": "Q9W0E1", "url": "https://omabrowser.org/oma/group/Q9W0E1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A2RSQ0-1", "protein_name": "DENN domain-containing protein 5B", "gene_name": "Dennd5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGSSAAPGPGSGSSPAACRFAHYFVLCGIDADSGLEPDELAGENFDQSPLRRTFKSKVLAHYPQNIEWNPFDQDAVNMLCMPKGLSFRTQADNKEPQFHSFIITREDGSRTYGFVLTFYEEVTSKQICTAMQTLYQMHNAEQYSSVYASSSCSMDSLASSIDEGDATSLLKLQRYNSYDINRDTLYVSKSICLITPLPFMQACKKFLFQLHKAVTSQQPPPLPLESYIHNILYEVPLPPPGRSLKFYGVYEPVICQRPGPNELPLSDYPLREACELLGLENLVQVFTCVLLEMQTLLYSQDYQRLMTVAEGITTLLFPFQWQHVYVPILPASLLHFLDAPVPYLMGLQSKEGTDRSKLELPQEANLCFVDIDNHFIELPEEFPQFPNKVDFIQELSEVLLQFGIPPEGSLHSSESATKLKNMVLKDLANDKKNGNVPNNSVSVYELLKGSETIARLQALAKRTGVTMEKIDLPASLSEKEKDLKLQCEEADLRDSQLNVQLREVFANRFTQMFADYEAFVIQTAQDMESWLTNREQMQNFDKASFLSDQPEPYLPFLSRFIETQMFATFIDNKIMSQWEEKDPLLRVFDSRIEKIRLYNVRAPTLRTSIYQKCSSLKEAAQSIEQRLMKMDHTAIHPHLLDMKIGQGKYEQGFFPKLQSDVLATGPANNNRWVSRSATAQRRKERLRQSSEHIGLDSDLREKYMQEARSLGKNLRQPKLSDLSPAVIAQTNWKFVEGLLKECRMKTKRMLVEKMGHEAVELGHGEANITGLEENTLIASLCDLLERIWSHGLLVKQGKSALWSHLLQFQDREEKQEHLTDSPVALGPERRKSDSGVMLPTLRVSLIQDMRHIQNMTEIKTDVGRARAWIRLSLEKKLLSQHLKQLLSNQPLTKKLYKRYAFLRCEEEREQFLYHLLSLNAVDYFCFTSVFTTIMIPYRSVIIPIKKLSNAIITSNPWICVSGELGDTGVMQIPKNLLEMTFECQNLGKLTTVQIGHDNSGLLAKWLVDCVMVRNEITGHTYRFPCGRWLGKGVDDGSLERILIGELMTSASDEDLGKQCRTPPQQKSPTTTRRLSITSLTGKPAKPNAGQIQEGIGEAVNNIVKHFHKPEKERGSLTVLLCGENGLVAALEQVFHHGFKSARIFHKNVFIWDFVEKAVAYFETTDQILDNEGDVLIQKPSSKTFCHYVNAINTAPRNIGKDGKFQILVCLGTRDHLLPQWIPLLAECPAITRMYEENALLRDHMTVNSLIRILQTIQDFTIVLEGSLIKGVDV", "length": 1274 }, "evidence": [ { "id": "HGNC:28338", "url": "https://alliancegenome.org/gene/HGNC:28338#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-2248", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-2248#orthology", "database": "AGR" }, { "id": "MGI:2444273", "url": "https://alliancegenome.org/gene/MGI:2444273#orthology", "database": "AGR" }, { "id": "RGD:2318606", "url": "https://alliancegenome.org/gene/RGD:2318606#orthology", "database": "AGR" }, { "id": "FB:FBgn0035229", "url": "https://alliancegenome.org/gene/FB:FBgn0035229#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3V7Q0-1", "protein_name": "DENN domain-containing protein 5A", "gene_name": "Dennd5a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGGGGGGGSAPSRFADYFVICGLDTETGLEPDELSALCQYIQASKARDGASPFISSTTEGENFEQTPLRRTFKSKVLARYPENVDWNPFDQDAVGMLCMPKGLAFKTQADPREPQFHAFIITREDGSRTFGFALTFYEEVTSKQICSAMQTLYHMHNAEYDVLHAPLADGGDQSGMEDGEGIPGTKLQRFNSYDISRDTLYVSKCICLITPMSFMKACRSVLQQLHQAVTSPQPPPLPLESYIYNVLYEVPLPPPGRSLKFSGVYGPIICQRPSTNELPLFDFPVKEVFELLGVENVFQLFTCALLEFQILLYSQHYQRLMTVAETITALMFPFQWQHVYVPILPASLLHFLDAPVPYLMGLHSNGLDDRSKLELPQEANLCFVDVDNHFIELPEDLPQFPNKLEFVQEVSEILMAFGVPPEGNLHCSESASKLKRIRASELVSDKKNGNIAGSPLHSYELLKENETIARLQALVKRTGVSLEKLEVREDPSSNKDFKVQCDEEELRIYQLNIQIREVFANRFTQMFADYEVFVIQPSQDKESWLSNREQMQNFDKASFLSDQPEPYLPFLSRFLETQMFASFIDNKIMCHDDDDKDPVLRVFDSRVDKIRLLNVRTPTLRTSMYQKCTTVDEAEKAIELRLAKIDHTAVHPHLLDMKIGQGKYEPGFFPKLQSDVLCTGPASNKWTKRNAPAQWRRKDRQKQHTEHLRLDNDQREKYIQEARNMGSTIRQPKLSNLSPSVIAQTNWKFVEGLLKECRNKTKRMLVEKMGREAVELGHGEVNITGVEENTLIASLCDLLERIWSHGLQVKQGKSALWSHLLHYQENRQRKLTSGSLSTSGILLDSERRKSDASAVMSPLRVSLIQDMRHIQNIGEIKTDVGKARAWVRLSMEKKLLSRHLKQLLSDHELTKKLYKRYAFLRCDDEKEQFLYHLLSFNAVDYFCFTNVFTTILIPYHILIVPSKKLGGSMFTANPWICISGELGETQILQIPRNVLEMTFECQNLGKLTTVQIGHDNSGLYAKWLVEYVMVRNEITGHTYKFPCGRWLGKGMDDGSLERVLVGELLTSLPEVDERPCRTPPLQQSPSVIRRLVTISPNNKPKLNTGQIQESIGEAVNGIVKHFHKPEKERGSLTLLLCGECGLVSALEQAFQHGFKSPRLFKNVFIWDFLEKAQTYYETLEQNDVVPEENWHTRARNFCRFVTAVNNTPRNIGKDGKFQMLVCLGARDHLLHHWIALLADCPITAHMYEDVALIKDHTLVNSLIRVLQTLQEFNITLDTSLVKGIDI", "length": 1287 }, "evidence": [ { "id": "HGNC:19344", "url": "https://alliancegenome.org/gene/HGNC:19344#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-071211-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-071211-1#orthology", "database": "AGR" }, { "id": "MGI:1201681", "url": "https://alliancegenome.org/gene/MGI:1201681#orthology", "database": "AGR" }, { "id": "RGD:1306759", "url": "https://alliancegenome.org/gene/RGD:1306759#orthology", "database": "AGR" }, { "id": "FB:FBgn0035229", "url": "https://alliancegenome.org/gene/FB:FBgn0035229#orthology", "database": "AGR" }, { "id": "Q9W0E1", "url": "https://omabrowser.org/oma/group/Q9W0E1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6IQ26-1", "protein_name": "DENN domain-containing protein 5A", "gene_name": "DENND5A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSGGGGGGGSAPSRFADYFVICGLDTETGLEPDELSALCQYIQASKARDGASPFISSTTEGENFEQTPLRRTFKSKVLARYPENVEWNPFDQDAVGMLCMPKGLAFKTQADPREPQFHAFIITREDGSRTFGFALTFYEEVTSKQICSAMQTLYHMHNAEYDVLHAPPADDRDQSSMEDGEDTPVTKLQRFNSYDISRDTLYVSKCICLITPMSFMKACRSVLEQLHQAVTSPQPPPLPLESYIYNVLYEVPLPPPGRSLKFSGVYGPIICQRPSTNELPLFDFPVKEVFELLGVENVFQLFTCALLEFQILLYSQHYQRLMTVAETITALMFPFQWQHVYVPILPASLLHFLDAPVPYLMGLHSNGLDDRSKLELPQEANLCFVDIDNHFIELPEDLPQFPNKLEFVQEVSEILMAFGIPPEGNLHCSESASKLKRLRASELVSDKRNGNIAGSPLHSYELLKENETIARLQALVKRTGVSLEKLEVREDPSSNKDLKVQCDEEELRIYQLNIQIREVFANRFTQMFADYEVFVIQPSQDKESWFTNREQMQNFDKASFLSDQPEPYLPFLSRFLETQMFASFIDNKIMCHDDDDKDPVLRVFDSRVDKIRLLNVRTPTLRTSMYQKCTTVDEAEKAIELRLAKIDHTAIHPHLLDMKIGQGKYEPGFFPKLQSDVLSTGPASNKWTKRNAPAQWRRKDRQKQHTEHLRLDNDQREKYIQEARTMGSTIRQPKLSNLSPSVIAQTNWKFVEGLLKECRNKTKRMLVEKMGREAVELGHGEVNITGVEENTLIASLCDLLERIWSHGLQVKQGKSALWSHLLHYQDNRQRKLTSGSLSTSGILLDSERRKSDASSLMPPLRISLIQDMRHIQNIGEIKTDVGKARAWVRLSMEKKLLSRHLKQLLSDHELTKKLYKRYAFLRCDDEKEQFLYHLLSFNAVDYFCFTNVFTTILIPYHILIVPSKKLGGSMFTANPWICISGELGETQIMQIPRNVLEMTFECQNLGKLTTVQIGHDNSGLYAKWLVEYVMVRNEITGHTYKFPCGRWLGKGMDDGSLERILVGELLTSQPEVDERPCRTPPLQQSPSVIRRLVTISPNNKPKLNTGQIQESIGEAVNGIVKHFHKPEKERGSLTLLLCGECGLVSALEQAFQHGFKSPRLFKNVFIWDFLEKAQTYYETLEKNEVVPEENWHTRARNFCRFVTAINNTPRNIGKDGKFQMLVCLGARDHLLHHWIALLADCPITAHMYEDVALIKDHTLVNSLIRVLQTLQEFNITLETSLVKGIDI", "length": 1287 }, "evidence": [ { "id": "HGNC:19344", "url": "https://alliancegenome.org/gene/HGNC:19344#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-071211-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-071211-1#orthology", "database": "AGR" }, { "id": "MGI:1201681", "url": "https://alliancegenome.org/gene/MGI:1201681#orthology", "database": "AGR" }, { "id": "RGD:1306759", "url": "https://alliancegenome.org/gene/RGD:1306759#orthology", "database": "AGR" }, { "id": "FB:FBgn0035229", "url": "https://alliancegenome.org/gene/FB:FBgn0035229#orthology", "database": "AGR" }, { "id": "Q9W0E1", "url": "https://omabrowser.org/oma/group/Q9W0E1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6NXD8-1", "protein_name": "DENN domain-containing protein 5B", "gene_name": "dennd5b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSATMSGSGSAPCRFAHYFIVCGLDDETGLEPDALAALYQWLEADRQGKDPEATAAGENFDQSPLKRTFKSKVLAHYPENIECNPFDQDAVNMLCMPKGLSFRTQRDSLAPHFHSFLITREDGSRTYGFVHTFYEEVTSPQICSAMQTLHQMHQAEHNTSAQNCTSSSSSSSSSSSSSSMDSLSSSLDDVDSPSAHGGRRTCEGYDSIRDTLYVSKAMCLIAPMPFMHACKRFLAQMHRAVSCSPPPPLPLESYIYNVLYEVPLPASGRSLKFHGVYEPILCQRPGVGELPLADFPLADAFRLLGVENLVQLFTCVLLEMQILLYSQDYQRLMVVAEGITTLLFPFQWQHVYVPILPASLLHFLDAPVPYLMGLQSKEGTDRSKLELPQEANLCFVDIDNHCIELPEDFPQFPNRSEFIQELSEVLLSFGQSPEGGSSSPEPAVMSLQTSVLEKELKSTSLRELVDDKTNGNLGGEALDVLELLQGNPTLERLQALAKRTGVKVARLEALAAGQKGDEGVGGRSPVEEEELRNAKLNVQLREVFAARFATMFADYESFVIQNSPDLESWLTNREQMHNFDKASFLSDQPEPYLPFLSHFIETQMFATFIDNKIMSQWEEKEPLLRVFDGRIEKARLYNVRAPSLRSSVYQKCTFLKESAQAIEQRLRKIDHTAIHPHLLDMKIGQGKYQQGFFPKLQADVLASGPTSNKWSNRTCSTQRRVERHRQQNEHLVLDNELKEKYMQEARNLGKNLRQPKLSDLSPAVIAQTNWKFVEGLLKECKMKTKRMLVEKMGREAVELGHGEANITGLEENTLIASLCDLLERIWSHGLQVKQGKSALWSHLLHYQAREEKNEQQLESPVSNGQERRKTESSVGLPGLRVSVIQDMRHIQNMAEIKTDVGRARAWIRLSLEKKLLSQHLKQLLSNQALTKKLYKRYAFLRCEEEKEQFLFHLLSLNAVDYFCFTSVFTTIMIPYRAVIIPIKKLSNAMTTSNPWLCVSGELGDSGILQITKNILEMTFDCQNLGKLTTVQLGHDNSGLLAKWLVDCVMVRNEITGHTYKFPCGRWLGKGVDDGSLERVLIGEFVVPCGDDEGGRGSKTPPLQRSPSQIRRISITSLTGKGNKPTTVQIQESIGEAVNNIIKHFHKPEKERGSLTVLLCGEGGLVWALEQFFHHGFRSARIFQKNVFVWDFFERIVAFMENRDQTGDLQESPEPLSLNSESLCRYVNAINNMPRNIGKDGKFQLLVCLGARDRLLPQWLPLLAESPVITRMYEENALLRDKLTVSSLLGVLETLHDFPITLETSLTKSVEL", "length": 1311 }, "evidence": [ { "id": "HGNC:28338", "url": "https://alliancegenome.org/gene/HGNC:28338#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-2248", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-2248#orthology", "database": "AGR" }, { "id": "MGI:2444273", "url": "https://alliancegenome.org/gene/MGI:2444273#orthology", "database": "AGR" }, { "id": "RGD:2318606", "url": "https://alliancegenome.org/gene/RGD:2318606#orthology", "database": "AGR" }, { "id": "FB:FBgn0035229", "url": "https://alliancegenome.org/gene/FB:FBgn0035229#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6PAL8-1", "protein_name": "DENN domain-containing protein 5A", "gene_name": "Dennd5a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGGGGGGGSAPSRFADYFVICGLDTETGLEPDELSALCQYIQASKARDGASPFISSTTEGENFEQTPLRRTFKSKVLARYPENVDWNPFDQDAVGMLCMPKGLAFKTQADPREPQFHAFIITREDGSRTFGFALTFYEEVTSKQICSAMQTLYHMHNAEYDVLHAPLADGGDQSGMEDGEGIPGTKLQRFNSYDISRDTLYVSKCICLITPMSFMKACRSVLQQLHQAVTSPQPPPLPLESYIYNVLYEVPLPPPGRSLKFSGVYGPIICQRPSTNELPLFDFPVKEVFELLGVENVFQLFTCALLEFQILLYSQHYQRLMTVAETITALMFPFQWQHVYVPILPASLLHFLDAPVPYLMGLHSNGLDDRSKLELPQEANLCFVDVDNHFIELPEDLPQFPNKLEFVQEVSEILMAFGVPPEGNLHCSESASKLKRIRASELVSDKRNGNIAGSPLHSYELLKENETIARLQALVKRTGVSLEKLEVREDPSSNKDFKVQCDEEELRIYQLNIQIREVFANRFTQMFADYEVFVIQPSQDKESWFTNREQMQNFDKASFLSDQPEPYLPFLSRFLETQMFASFIDNKIMCHDDDDKDPVLRVFDSRVDKIRLLNVRTPTLRTSMYQKCTTVDEAEKAIELRLAKIDHTAVHPHLLDMKIGQGKYEPGFFPKLQSDVLCTGPASNKWTKRNAPAQWRRKDRQKQHTEHLRLDNDQREKYIQEARNMGSTIRQPKLSNLSPSVIAQTNWKFVEGLLKECRNKTKRMLVEKMGREAVELGHGEVNITGVEENTLIASLCDLLERIWSHGLQVKQGKSALWSHLLHYQENRQRKLTSGSLSTSGILLDSERRKSDASAVMSPLRISLIQDMRHIQNIGEIKTDVGKARAWVRLSMEKKLLSRHLKQLLSDHELTKKLYKRYAFLRCDDEKEQFLYHLLSFNAVDYFCFTNVFTTILIPYHILIVPSKKLGGSMFTANPWICISGELGETQILQIPRNVLEMTFECQNLGKLTTVQIGHDNSGLYAKWLVECVMVRNEVTGHTYKFPCGRWLGKGMDDGSLERVLVGELLTSLPEVDERPCRTPPLQQSPSVIRRLVTISPNNKPKLNTGQIQESIGEAVNGIVKHFHKPEKERGSLTLLLCGECGLVSALEQAFQHGFKSPRLFKNVFIWDFLEKAQTYYETLEQNDVVPEENWHTRARNFCRFVTAVNNTPRNIGKDGKFQMLVCLGARDHLLHHWIALLADCPITAHMYEDVALIKDHTLVNSLIRVLQTLQEFNITLDTSLVKGIDI", "length": 1287 }, "evidence": [ { "id": "HGNC:19344", "url": "https://alliancegenome.org/gene/HGNC:19344#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-071211-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-071211-1#orthology", "database": "AGR" }, { "id": "MGI:1201681", "url": "https://alliancegenome.org/gene/MGI:1201681#orthology", "database": "AGR" }, { "id": "RGD:1306759", "url": "https://alliancegenome.org/gene/RGD:1306759#orthology", "database": "AGR" }, { "id": "FB:FBgn0035229", "url": "https://alliancegenome.org/gene/FB:FBgn0035229#orthology", "database": "AGR" }, { "id": "Q9W0E1", "url": "https://omabrowser.org/oma/group/Q9W0E1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6ZUT9-1", "protein_name": "DENN domain-containing protein 5B", "gene_name": "DENND5B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSGSCAAPGPGSGSSPAACRFAHYFVLCGIDADSGLEPDELAGENFDQSPLRRTFKSKVLAHYPQNIEWNPFDQDAVNMLCMPKGLSFRTQTDNKDPQFHSFIITREDGSRTYGFVLTFYEEVTSKQICTAMQTLYQMHNAEHYSSVYASSSCSMDSLASSLDEGDTTSLLKLQRYNSYDISRDTLYVSKSICLITPLPFMQACKKFLIQLYKAVTSQQPPPLPLESYIHNILYEVPLPPPGRSLKFYGVYEPVICQRPGPSELPLSDYPLREAFELLGLENLVQVFTCVLLEMQILLYSQDYQRLMTVAEGITTLLFPFQWQHVYVPILPASLLHFLDAPVPYLMGLQSKEGTDRSKLELPQEANLCFVDIDNHFIELPEEFPQFPNKVDFIQELSEVLVQFGIPPEGSLHCSESTSKLKNMVLKDLVNDKKNGNVCTNNISMYELLKGNETIARLQALAKRTGVAVEKMDLSASLGEKDKDLKLHCEEAELRDYQLNVQLREVFANRFTQMFADYEAFVIQTAQDMESWLTNREQMQNFDKASFLSDQPEPYLPFLSRFIETQMFATFIDNKIMSQWEEKDPLLRVFDTRIDKIRLYNVRAPTLRTSIYQKCSTLKEAAQSIEQRLMKMDHTAIHPHLLDMKIGQGKYEQGFFPKLQSDVLATGPTSNNRWVSRSATAQRRKERLRQHSEHVGLDNDLREKYMQEARSLGKNLRQPKLSDLSPAVIAQTNCKFVEGLLKECRMKTKRMLVEKMGHEAVELGHGEANITGLEENTLIASLCDLLERIWSHGLQVKQGKSALWSHLIQFQDREEKQEHLAESPVALGPERRKSDSGVMLPTLRVSLIQDMRHIQNMSEIKTDVGRARAWIRLSLEKKLLSQHLKQLLSNQPLTKKLYKRYAFLRCEEEREQFLYHLLSLNAVDYFCFTSVFTTIMIPYRSVIIPIKKLSNAIITSNPWICVSGELGDTGVMQIPKNLLEMTFECQNLGKLTTVQIGHDNSGLLAKWLVDCVMVRNEITGHTYRFPCGRWLGKGIDDGSLERILIGELMTSASDEDLVKQCRTPPQQKSPTTARRLSITSLTGKNNKPNAGQIQEGIGEAVNNIVKHFHKPEKERGSLTVLLCGENGLVAALEQVFHHGFKSARIFHKNVFIWDFIEKVVAYFETTDQILDNEDDVLIQKSSCKTFCHYVNAINTAPRNIGKDGKFQILVCLGTRDRLLPQWIPLLAECPAITRMYEESALLRDRMTVNSLIRILQTIQDFTIVLEGSLIKGVDV", "length": 1274 }, "evidence": [ { "id": "HGNC:28338", "url": "https://alliancegenome.org/gene/HGNC:28338#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-2248", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-2248#orthology", "database": "AGR" }, { "id": "MGI:2444273", "url": "https://alliancegenome.org/gene/MGI:2444273#orthology", "database": "AGR" }, { "id": "RGD:2318606", "url": "https://alliancegenome.org/gene/RGD:2318606#orthology", "database": "AGR" }, { "id": "FB:FBgn0035229", "url": "https://alliancegenome.org/gene/FB:FBgn0035229#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of Rab protein signal transduction", "id": "GO:0032483", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032483", "evidence": [ { "database": "UniProtKB", "id": "Q9W0E1", "url": "https://www.uniprot.org/uniprotkb/Q9W0E1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q9W0E1", "url": "https://www.uniprot.org/uniprotkb/Q9W0E1" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9W0E1", "url": "https://www.uniprot.org/uniprotkb/Q9W0E1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "Q9W0E1", "url": "https://www.uniprot.org/uniprotkb/Q9W0E1" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "Q9W0E1", "url": "https://www.uniprot.org/uniprotkb/Q9W0E1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1125, "end_pos": 1127, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1337, "end_pos": 1339, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1366, "end_pos": 1368, "annotation": "n_glycosylation_sequon" }, { "start_pos": 23, "end_pos": 25, "annotation": "n_glycosylation_sequon" }, { "start_pos": 27, "end_pos": 29, "annotation": "n_glycosylation_sequon" }, { "start_pos": 626, "end_pos": 628, "annotation": "n_glycosylation_sequon" }, { "start_pos": 829, "end_pos": 831, "annotation": "n_glycosylation_sequon" }, { "start_pos": 844, "end_pos": 846, "annotation": "n_glycosylation_sequon" }, { "start_pos": 982, "end_pos": 984, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9W0E1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W0E1" }, { "id": "PS50095", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50095" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PLAT", "eco_id": "ECO_0000259", "start_pos": 1095, "end_pos": 1203, "start_aa": "Leu", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q9W0E1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W0E1" }, { "id": "PS50826", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50826" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RUN", "eco_id": "ECO_0000259", "start_pos": 881, "end_pos": 1091, "start_aa": "Ile", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q9W0E1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W0E1" }, { "id": "PS50211", "database": "PROSITE", "url": 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"https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W0E2", "url": "https://www.uniprot.org/uniprotkb/Q9W0E2" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W0E2", "url": "https://www.uniprot.org/uniprotkb/Q9W0E2" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W0E2", "url": "https://www.uniprot.org/uniprotkb/Q9W0E2" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W0E2", "url": "https://www.uniprot.org/uniprotkb/Q9W0E2" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W0E2", "url": "https://www.uniprot.org/uniprotkb/Q9W0E2" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W0E2", "url": "https://www.uniprot.org/uniprotkb/Q9W0E2" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W0E2", "url": "https://www.uniprot.org/uniprotkb/Q9W0E2" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W0E2", "url": "https://www.uniprot.org/uniprotkb/Q9W0E2" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W0E2", "url": "https://www.uniprot.org/uniprotkb/Q9W0E2" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG12091", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG12091", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1A8D0-1", "protein_name": "Protein phosphatase", "gene_name": "PPTC7", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MFSVLSYGRLVARAVLGGLSQTDTRDYSLVTASCGFGKDFRKGILKKGMCYGDDACFVARHRTADVLGVADGVGGWRDYGVDPSQFSGTLMRTCERLVKEGRFVPSNPVGILTAGYCELLQNKVPLLGSSTACIVVLDRTSHRLHTANLGDSGFLVVRGGEVVHRSDEQQHYFNTPFQLSIAPPEAEGVVLSDSPDAADSTSFDVQLGDIILTATDGLFDNMPDYMILQELKKLKNSNYESIQQTARSIAEQAHELAYDPTYMSPFAQFACDNGLNVRGGKPDDITVLLSIVAEYTD", "length": 297 }, "evidence": [ { "id": "Q9W0E2", "url": "https://omabrowser.org/oma/group/Q9W0E2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0ACD6B694-1", "protein_name": "Protein phosphatase", "gene_name": "pptc7b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLSVLSYGRIVARAVLGGLSQTDGRDYSLITASCGFGKDFRKGILKKGMCYGDDACFIARHKSADVLGVADGVGGWRDYGVDPSQFSATLMKTCERLVKEGRFTPSSPVGILTSGYYELLQNKVPLLGSSTACIVVLDRRSHRIHTCNLGDSGFLVVRGGEVVHRSDEQQHYFNTPFQLSIAPPGAEGVVLSDSPEAADSSSFDVQLGDIILTATDGLFDNMPDYMILQELKKLKNTNYDSIQQTARSIAEQAHELAYDPNYMSPFAQFACDNGLNVRGGKPDDITVLLSIVAEYTD", "length": 297 }, "evidence": [ { "id": "MGI:2444593", "url": "https://alliancegenome.org/gene/MGI:2444593#orthology", "database": "AGR" }, { "id": "HGNC:30695", "url": "https://alliancegenome.org/gene/HGNC:30695#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D4A520-1", "protein_name": "Protein phosphatase", "gene_name": "Pptc7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSVLSYGRLVARAVLGGLSQTDPRAGGGGGGGSGDYGLVTAGCGFGKDFRKGLLKKGACYGDDACFVARHRSADVLGVADGVGGWRDYGVDPSQFSGTLMRTCERLVKEGRFVPSNPVGILTTSYCELLQNKVPLLGSSTACIVVLDRSSHRLHTANLGDSGFLVVRGGEVVHRSDEQQHYFNTPFQLSIAPPEAEGVVLSDSPDAADSTSFDVQLGDIILTATDGLFDNMPDYMILQELKKLKNSNYESIQRTARSIAEQAHELAYDPNYMSPFAQFACDNGLNVRGGKPDDITVLLSIVAEYTD", "length": 307 }, "evidence": [ { "id": "RGD:1310383", "url": "https://alliancegenome.org/gene/RGD:1310383#orthology", "database": "AGR" }, { "id": "MGI:2444593", "url": "https://alliancegenome.org/gene/MGI:2444593#orthology", "database": "AGR" }, { "id": "HGNC:30695", "url": "https://alliancegenome.org/gene/HGNC:30695#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-74", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-74#orthology", "database": "AGR" }, { "id": "FB:FBgn0035228", "url": "https://alliancegenome.org/gene/FB:FBgn0035228#orthology", "database": "AGR" }, { "id": "SGD:S000001118", "url": "https://alliancegenome.org/gene/SGD:S000001118#orthology", "database": "AGR" }, { "id": "Q9W0E2", "url": "https://omabrowser.org/oma/group/Q9W0E2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BEW5-1", "protein_name": "Protein phosphatase", "gene_name": "PPTC7", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MFSVLSYGRLVARAVLGGLSQTDPRAGGGGGGGGGDYGLVTAGCGFGKDFRKGLLKKGACYGDDACFVARHRSADVLGVADGVGGWRDYGVDPSQFSGTLMRTCERLVKEGRFVPSNPIGILTTSYCELLQNKVPLLGSSTACIVVLDRTSHRLHTANLGDSGFLVVRGGEVVHRSDEQQHYFNTPFQLSIAPPEAEGVVLSDSPDAADSTSFDVQLGDIILTATDGLFDNMPDYMILQELKKLKNSNYESIQQTARSIAEQAHELAYDPNYMSPFAQFACDNGLNVRGGKPDDITVLLSIVAEYTD", "length": 307 }, "evidence": [ { "id": "Q9W0E2", "url": "https://omabrowser.org/oma/group/Q9W0E2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RNM7-1", "protein_name": "Protein phosphatase", "gene_name": "PPTC7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFSVLSYGRLVARAVLGGLSQTDPRAGGGSGSGGGDYGLVTAGCGFGKDFRKGLLKKGACYGDDACFVARHRSADVLGVADGVGGWRDYGVDPSQFSGTLMRTCERLVKEGRFVPSNPIGILTTSYCELLQNKVPLLGSSTACIVVLDRTSHRLHTANLGDSGFLVVRGGEVVHRSDEQQHYFNTPFQLSIAPPEAEGVVLSDSPDAADSTSFDVQLGDIILTATDGLFDNMPDYMILQELKKLKNSNYESIQQTARSIAEQAHELAYDPNYMSPFAQFACDNGLNVRGGKPDDITVLLSIVAEYTD", "length": 307 }, "evidence": [ { "id": "Q9W0E2", "url": "https://omabrowser.org/oma/group/Q9W0E2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O64730-1", "protein_name": "Probable protein phosphatase 2C 26", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAIPVTRMMVPHAIPSLRLSHPNPSRVDFLCRCAPSEIQPLRPELSLSVGIHAIPHPDKVEKGGEDAFFVSSYRGGVMAVADGVSGWAEQDVDPSLFSKELMANASRLVDDQEVRYDPGFLIDKAHTATTSRGSATIILAMLEEVGILKIGNVGDCGLKLLREGQIIFATAPQEHYFDCPYQLSSEGSAQTYLDASFSIVEVQKGDVIVMGSDGLFDNVFDHEIVSIVTKHTDVAESSRLLAEVASSHSRDTEFESPYALEARAKGFDVPLWKKVLGKKLTGGKLDDVTVIVAKVVSS", "length": 298 }, "evidence": [ { "id": "Q9W0E2", "url": "https://omabrowser.org/oma/group/Q9W0E2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P38797-1", "protein_name": "Protein phosphatase 2C homolog 7, mitochondrial", "gene_name": "PTC7", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MFANVGFRTLRVSRGPLYGSCSQIISFSKRTFYSSAKSGYQSNNSHGDAYSSGSQSGPFTYKTAVAFQPKDRDDLIYQKLKDSIRSPTGEDNYFVTSNNVHDIFAGVADGVGGWAEHGYDSSAISRELCKKMDEISTALAENSSKETLLTPKKIIGAAYAKIRDEKVVKVGGTTAIVAHFPSNGKLEVANLGDSWCGVFRDSKLVFQTKFQTVGFNAPYQLSIIPEEMLKEAERRGSKYILNTPRDADEYSFQLKKKDIIILATDGVTDNIATDDIELFLKDNAARTNDELQLLSQKFVDNVVSLSKDPNYPSVFAQEISKLTGKNYSGGKEDDITVVVVRVD", "length": 343 }, "evidence": [ { "id": "RGD:1310383", "url": "https://alliancegenome.org/gene/RGD:1310383#orthology", "database": "AGR" }, { "id": "MGI:2444593", "url": "https://alliancegenome.org/gene/MGI:2444593#orthology", "database": "AGR" }, { "id": "HGNC:30695", "url": "https://alliancegenome.org/gene/HGNC:30695#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-74", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-74#orthology", "database": "AGR" }, { "id": "FB:FBgn0035228", "url": "https://alliancegenome.org/gene/FB:FBgn0035228#orthology", "database": "AGR" }, { "id": "SGD:S000001118", "url": "https://alliancegenome.org/gene/SGD:S000001118#orthology", "database": "AGR" }, { "id": "Q9W0E2", "url": "https://omabrowser.org/oma/group/Q9W0E2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q5U3N5-1", "protein_name": "Protein phosphatase PTC7 homolog", "gene_name": "pptc7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLSVLSYGRLVARAVIGGLSQTDSRDYSLVSASFGFGKDFRKGILKKGMCYGDDACFIARHRSADVLGVADGVGGWRDYGVDPSQFSGTLMRTCERLVKEGRFVPSNPVGILTTSYYELLQNKVPLLGSSTACIVVLDRQSHRLHTANLGDSGFLVVRGGEVVHRSDEQQHYFNTPFQLSIAPPEAEGSVLSDSPDAADSSSFDVQLGDIILTATDGLFDNMPDYMILQELKKLKNTNYESTQQTAKSIAEQAHVLAYDPNYMSPFAQFACDNGLNVRGGKPDDITVLLSIVAEYTD", "length": 297 }, "evidence": [ { "id": "RGD:1310383", "url": "https://alliancegenome.org/gene/RGD:1310383#orthology", "database": "AGR" }, { "id": "MGI:2444593", "url": "https://alliancegenome.org/gene/MGI:2444593#orthology", "database": "AGR" }, { "id": "HGNC:30695", "url": "https://alliancegenome.org/gene/HGNC:30695#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-74", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-74#orthology", "database": "AGR" }, { "id": "FB:FBgn0035228", "url": "https://alliancegenome.org/gene/FB:FBgn0035228#orthology", "database": "AGR" }, { "id": "SGD:S000001118", "url": "https://alliancegenome.org/gene/SGD:S000001118#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6NVE9-1", "protein_name": "Protein phosphatase PTC7 homolog", "gene_name": "Pptc7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSVLSYGRLVARAVLGGLSQTDPRAGGGGGGGGGSSGDYGLVTAGCGFGKDFRKGLLKKGACYGDDACFVARHRSADVLGVADGVGGWRDYGVDPSQFSGTLMRTCERLVKEGRFVPSNPVGILTTSYCELLQNKVPLLGSSTACIVVLDRSSHRLHTANLGDSGFLVVRGGEVVHRSDEQQHYFNTPFQLSIAPPEAEGVVLSDSPDAADSTSFDVQLGDIILTATDGLFDNMPDYMILQELKKLKNSNYESIQRTARSIAEQAHELAYDPNYMSPFAQFACDNGLNVRGGKPDDITVLLSIVAEYTD", "length": 310 }, "evidence": [ { "id": "RGD:1310383", "url": "https://alliancegenome.org/gene/RGD:1310383#orthology", "database": "AGR" }, { "id": "MGI:2444593", "url": "https://alliancegenome.org/gene/MGI:2444593#orthology", "database": "AGR" }, { "id": "HGNC:30695", "url": "https://alliancegenome.org/gene/HGNC:30695#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-74", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-74#orthology", "database": "AGR" }, { "id": "FB:FBgn0035228", "url": "https://alliancegenome.org/gene/FB:FBgn0035228#orthology", "database": "AGR" }, { "id": "SGD:S000001118", "url": "https://alliancegenome.org/gene/SGD:S000001118#orthology", "database": "AGR" }, { "id": "Q9W0E2", "url": "https://omabrowser.org/oma/group/Q9W0E2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NI37-1", "protein_name": "Protein phosphatase PTC7 homolog", "gene_name": "PPTC7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFSVLSYGRLVARAVLGGLSQTDPRAGGGGGGDYGLVTAGCGFGKDFRKGLLKKGACYGDDACFVARHRSADVLGVADGVGGWRDYGVDPSQFSGTLMRTCERLVKEGRFVPSNPIGILTTSYCELLQNKVPLLGSSTACIVVLDRTSHRLHTANLGDSGFLVVRGGEVVHRSDEQQHYFNTPFQLSIAPPEAEGVVLSDSPDAADSTSFDVQLGDIILTATDGLFDNMPDYMILQELKKLKNSNYESIQQTARSIAEQAHELAYDPNYMSPFAQFACDNGLNVRGGKPDDITVLLSIVAEYTD", "length": 304 }, "evidence": [ { "id": "RGD:1310383", "url": "https://alliancegenome.org/gene/RGD:1310383#orthology", "database": "AGR" }, { "id": "MGI:2444593", "url": "https://alliancegenome.org/gene/MGI:2444593#orthology", "database": "AGR" }, { "id": "HGNC:30695", "url": "https://alliancegenome.org/gene/HGNC:30695#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-74", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-74#orthology", "database": "AGR" }, { "id": "FB:FBgn0035228", "url": "https://alliancegenome.org/gene/FB:FBgn0035228#orthology", "database": "AGR" }, { "id": "SGD:S000001118", "url": "https://alliancegenome.org/gene/SGD:S000001118#orthology", "database": "AGR" }, { "id": "Q9W0E2", "url": "https://omabrowser.org/oma/group/Q9W0E2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VAH4-1", "protein_name": "Protein phosphatase PTC7 homolog fig", "gene_name": "fig", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MITCLRNWPLLLKRFSVHQIHQFTQLSGRFERPPQSGKSSRDPYLVTVVQGRSKKPRFPGERSNQRFGEDSWFVSSTPLAEVMGVADGVGGWRDLGVDAGRFAKELMSCCSGQTQLSDFDGRSPRNMLIAGFQELSHREHPVVGSSTACLATMHRKDCTLYTANLGDSGFLVVRNGRVLHRSVEQTHDFNTPYQLTVPPEDRKESYYCDKPEMAVSTRHSLLPGDLVLLATDGLFDNMPESMLLSILNGLKERGEHDLLVGASRVVEKARELSMNASFQSPFAIKARQHNVSYSGGGKPDDITLILSSVEVPNA", "length": 314 }, "evidence": [ { "id": "RGD:1310383", "url": "https://alliancegenome.org/gene/RGD:1310383#orthology", "database": "AGR" }, { "id": "MGI:2444593", "url": "https://alliancegenome.org/gene/MGI:2444593#orthology", "database": "AGR" }, { "id": "HGNC:30695", "url": "https://alliancegenome.org/gene/HGNC:30695#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-74", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-74#orthology", "database": "AGR" }, { "id": "SGD:S000001118", "url": "https://alliancegenome.org/gene/SGD:S000001118#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W3R1-1", "protein_name": "Protein phosphatase", "gene_name": "Dmel\\CG15035", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDVETSLDIEEMRRRIQQGINRCCEQLLEIAMILTHKGGQVLNRLKGASFPELAQNSENIGNGSMSENQNQRLDPMTSAQYTTLGFGNFDGEGDYLRQKNKINIQLPRLVSVTCGFAKDHIRYPEYNRGKFGEDAWFMSSSPQACIMGVADGVGGWRNYGVDPGKFSMTLMRSCERMSHAPDFKPNRPEILLERAYFDLLDQKCPIVGSCTACILALKRDDSTLYAANIGDSGFLVVRSGKVVCRSQEQQHQFNTPYQLASPPPGYDFDAVSDGPESADTIQFPMQLGDVILLATDGVYDNVPESFLVEVLTEMSGISNPVRLQMAANTVALMARTLSFSPKHDSPFSQNARKHDIDAWGGKPDDITVLLASVV", "length": 374 }, "evidence": [ { "id": "RGD:1310383", "url": "https://alliancegenome.org/gene/RGD:1310383#orthology", "database": "AGR" }, { "id": "MGI:2444593", "url": "https://alliancegenome.org/gene/MGI:2444593#orthology", "database": "AGR" }, { "id": "HGNC:30695", "url": "https://alliancegenome.org/gene/HGNC:30695#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-74", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-74#orthology", "database": "AGR" }, { "id": "SGD:S000001118", "url": "https://alliancegenome.org/gene/SGD:S000001118#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9W0E2", "url": "https://www.uniprot.org/uniprotkb/Q9W0E2" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "Q9W0E2", "url": "https://www.uniprot.org/uniprotkb/Q9W0E2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9W0E2", "url": "https://www.uniprot.org/uniprotkb/Q9W0E2" } ], "pmid": "" }, { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "Q9W0E2", "url": "https://www.uniprot.org/uniprotkb/Q9W0E2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of ubiquinone biosynthetic process", "id": "GO:0010795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010795", "evidence": [ { "database": "UniProtKB", "id": "Q9W0E2", "url": "https://www.uniprot.org/uniprotkb/Q9W0E2" } ], "pmid": "" }, { "name": "positive regulation of ubiquinone biosynthetic process", "id": "GO:1904775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904775", "evidence": [ { "database": "UniProtKB", "id": "Q9W0E2", "url": "https://www.uniprot.org/uniprotkb/Q9W0E2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20629", "name": "", "equation": "O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q05547-1", "Q27884-1", "Q7K4Q5-1", "Q9VAH4-1", "A8DYY5-1", "O76932-1", "P11612-1", "P40421-1", "P48461-1", "Q6NN85-1", "Q86BN8-1", "Q9VJ07-1", "P12982-1", "P48462-1", "M9PFN0-1", "O46084-1", "Q9VRG7-1", "Q27889-1", "Q9VXF1-1", "Q9VVW5-1", "Q9VWF4-1", "P48456-1", "X2JEB8-1", "Q9VWE4-1", "P23696-1", "Q9VQL9-1", "Q9XZ16-1", "M9PI51-1", "Q7KVM5-1", "Q9W3R1-1", "Q9W173-1", "Q9W0E2-1", "Q9W2A5-1", "Q9W147-1", "Q9VLW7-1" ], "evidence": [ { "id": "20629", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20629" } ] }, { "id": "47004", "name": "", "equation": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q05547-1", "Q27884-1", "Q7K4Q5-1", "Q9VAH4-1", "A8DYY5-1", "O76932-1", "P11612-1", "P40421-1", "P48461-1", "Q6NN85-1", "Q9VJ07-1", "P12982-1", "P48462-1", "Q86BN8-1", "O46084-1", "Q9VRG7-1", "Q27889-1", "Q9VXF1-1", "Q9VVW5-1", "Q9VWF4-1", "P48456-1", "X2JEB8-1", "Q9VWE4-1", "P23696-1", "Q9VQL9-1", "Q9XZ16-1", "M9PI51-1", "Q7KVM5-1", "Q9W3R1-1", "Q9W173-1", "Q9W0E2-1", "Q9W2A5-1", "Q9W147-1", "Q9VLW7-1" ], "evidence": [ { "id": "47004", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/47004" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A8DYY5", "gene_name": "", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A8DYY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8DYY5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A8DYY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8DYY5" } ] } ] }, { "uniprot_ac": "M9PFN0", "gene_name": "hzg", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "M9PFN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9PFN0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "M9PFN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9PFN0" } ] } ] }, { "uniprot_ac": "M9PI51", "gene_name": "Dmel\\CG10089", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "M9PI51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9PI51" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "M9PI51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9PI51" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "M9PI51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9PI51" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "M9PI51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9PI51" } ] } ] }, { "uniprot_ac": "O46084", "gene_name": "Pgam5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O46084", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O46084" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O46084", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O46084" } ] } ] }, { "uniprot_ac": "O76932", "gene_name": "Pp4-19C", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O76932", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O76932" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O76932", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O76932" } ] } ] }, { "uniprot_ac": "P11612", "gene_name": "PpY-55A", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P11612", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11612" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P11612", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11612" } ] } ] }, { "uniprot_ac": "P12982", "gene_name": "Pp1-87B", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P12982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P12982" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P12982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P12982" } ] } ] }, { "uniprot_ac": "P23696", "gene_name": "mts", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P23696", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P23696" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P23696", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P23696" } ] } ] }, { "uniprot_ac": "P40421", "gene_name": "rdgC", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P40421", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P40421" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P40421", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P40421" } ] } ] }, { "uniprot_ac": "P48456", "gene_name": "CanA1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P48456", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48456" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P48456", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48456" } ] } ] }, { "uniprot_ac": "P48461", "gene_name": "Pp1alpha-96A", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P48461", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48461" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P48461", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48461" } ] } ] }, { "uniprot_ac": "P48462", "gene_name": "flw", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P48462", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48462" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P48462", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48462" } ] } ] }, { "uniprot_ac": "Q05547", "gene_name": "Pp1-13C", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q05547", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05547" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q05547", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05547" } ] } ] }, { "uniprot_ac": "Q27884", "gene_name": "PpV", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q27884", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q27884" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q27884", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q27884" } ] } ] }, { "uniprot_ac": "Q27889", "gene_name": "Pp2B-14D", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q27889", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q27889" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q27889", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q27889" } ] } ] }, { "uniprot_ac": "Q6NN85", "gene_name": "ssh", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q6NN85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6NN85" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q6NN85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6NN85" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q6NN85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6NN85" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q6NN85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6NN85" } ] } ] }, { "uniprot_ac": "Q7K4Q5", "gene_name": "", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q7K4Q5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7K4Q5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q7K4Q5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7K4Q5" } ] } ] }, { "uniprot_ac": "Q7KVM5", "gene_name": "PpN58A", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q7KVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7KVM5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q7KVM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7KVM5" } ] } ] }, { "uniprot_ac": "Q86BN8", "gene_name": "PTPMT1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q86BN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q86BN8" } ] }, { "ec_number": "3.1.3.27", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + phosphate.", "evidence": [ { "id": "Q86BN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q86BN8" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q86BN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q86BN8" } ] }, { "ec_number": "3.1.3.27", "activity": "", "evidence": [ { "id": "Q86BN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q86BN8" } ] } ] }, { "uniprot_ac": "Q9VAH4", "gene_name": "fig", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q9VAH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VAH4" } ] } ] }, { "uniprot_ac": "Q9VJ07", "gene_name": "Phlpp", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q9VJ07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJ07" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q9VJ07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJ07" } ] } ] }, { "uniprot_ac": "Q9VLW7", "gene_name": "Cdc14", "activity": [ { "ec_number": "3.1.3.-", "activity": "", "evidence": [ { "id": "Q9VLW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VLW7" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q9VLW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VLW7" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q9VLW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VLW7" } ] } ] }, { "uniprot_ac": "Q9VQL9", "gene_name": "PpD6", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q9VQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQL9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q9VQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQL9" } ] } ] }, { "uniprot_ac": "Q9VRG7", "gene_name": "Dd", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q9VRG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VRG7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q9VRG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VRG7" } ] } ] }, { "uniprot_ac": "Q9VVW5", "gene_name": "Mkp3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q9VVW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVW5" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q9VVW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVW5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q9VVW5", "database": "UniProtKB", "url": 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"IPR011701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050327", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050327", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG13907", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG13907", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MYEEKQM", "url": "https://omabrowser.org/oma/group/MYEEKQM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W0L6", "url": "https://www.orthodb.org/?gene=Q9W0L6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11360", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11360", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11360:SF286", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11360:SF286", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-210991", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-210991", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-433692", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-433692", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-9749641", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9749641", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001286894", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001286894", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W0L6", "url": "https://www.uniprot.org/uniprotkb/Q9W0L6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W0L6-1", "url": "https://www.uniprot.org/uniprotkb/Q9W0L6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVDTNSSNPGIVGGNSASSARLRRFERTDSELACEEAARLTAEQSPEDEDNQDNDEDDDDEESVYGELPPPPDGGYGWVICFASFMCNMIVDGIAYTFGIFLEEFVAYFHEGKGTVAWVGSLLSGVYLSAGPIVSALANKYGCRAVCIAGSIIACIAFVLSTFSTNVSMLMATYGFMGGFGFGMIYLPAVVAVGYYFETKRSLATGIAVCGSGFGTFAFAPLATYLLEEYGWKNALLIFAGLILNCAIFGAMMRPLTYPKKKKQKPLMQRMYEEKQLQLERGSFAGSHFMVQLPDGTIERKLKMPLNADPGVHSSLNLELLAQQAGGGGLHPVSTLPTITESKVVDVHRQNGAQSPPNGDSNGQLSARSAAGAVGRRPHRNSESENSPYHSQDAMTRNASQPAFLAGDHQSLPKNGSVPAFNTRVRKTSASERFQPSLAAIRATSRGDLEAGAGGDFASSKLSLSQRQGGSQTGSSGRMVRPMSRKDIFYSGSVTNLPQYQSQKSLANYRNSVLSLTKYEKSMQSVAKLDPLAEAEKHREEYDLCPCLGIPDSVKSVVNTMLDVSLLKDPVFMLIGVSNIFGMAGLYVPFVYLVDAAKEHDIPKNDAAMLLSIIGITNTVGRVFCGWVADLPQVNSLLLNNCCLLVSTIAVTLTPLCYSYAAYITMSIFFGLAISGYISLTSIILVDLLGLDKLTNAFGLLILFRGFAALIGTPLAGAIYDMTHTYDLPFYMAGALFGISTITSFLAPCLKRCSPSEETPVHVETLTPIDEEQGEDAEDDEDQPITIVPKIIKTLASPQQEEGHPQFPQKTSESKL", "length": 816, "header": "tr|Q9W0L6-1|Q9W0L6_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG13907 PE=1 SV=1 CANONICAL=Q9W0L6-1" }, "isoforms": [ { "isoform_ac": "Q9W0L6-1", "url": "https://www.uniprot.org/uniprotkb/Q9W0L6/entry#Q9W0L6-1", "sequence": { "sequence": "MVDTNSSNPGIVGGNSASSARLRRFERTDSELACEEAARLTAEQSPEDEDNQDNDEDDDDEESVYGELPPPPDGGYGWVICFASFMCNMIVDGIAYTFGIFLEEFVAYFHEGKGTVAWVGSLLSGVYLSAGPIVSALANKYGCRAVCIAGSIIACIAFVLSTFSTNVSMLMATYGFMGGFGFGMIYLPAVVAVGYYFETKRSLATGIAVCGSGFGTFAFAPLATYLLEEYGWKNALLIFAGLILNCAIFGAMMRPLTYPKKKKQKPLMQRMYEEKQLQLERGSFAGSHFMVQLPDGTIERKLKMPLNADPGVHSSLNLELLAQQAGGGGLHPVSTLPTITESKVVDVHRQNGAQSPPNGDSNGQLSARSAAGAVGRRPHRNSESENSPYHSQDAMTRNASQPAFLAGDHQSLPKNGSVPAFNTRVRKTSASERFQPSLAAIRATSRGDLEAGAGGDFASSKLSLSQRQGGSQTGSSGRMVRPMSRKDIFYSGSVTNLPQYQSQKSLANYRNSVLSLTKYEKSMQSVAKLDPLAEAEKHREEYDLCPCLGIPDSVKSVVNTMLDVSLLKDPVFMLIGVSNIFGMAGLYVPFVYLVDAAKEHDIPKNDAAMLLSIIGITNTVGRVFCGWVADLPQVNSLLLNNCCLLVSTIAVTLTPLCYSYAAYITMSIFFGLAISGYISLTSIILVDLLGLDKLTNAFGLLILFRGFAALIGTPLAGAIYDMTHTYDLPFYMAGALFGISTITSFLAPCLKRCSPSEETPVHVETLTPIDEEQGEDAEDDEDQPITIVPKIIKTLASPQQEEGHPQFPQKTSESKL", "length": 816, "header": "tr|Q9W0L6-1|Q9W0L6_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG13907 PE=1 SV=1 CANONICAL=Q9W0L6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W0L6", "url": "https://www.uniprot.org/uniprotkb/Q9W0L6" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W0L6", "url": "https://www.uniprot.org/uniprotkb/Q9W0L6" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W0L6", "url": "https://www.uniprot.org/uniprotkb/Q9W0L6" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W0L6", "url": "https://www.uniprot.org/uniprotkb/Q9W0L6" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W0L6", "url": "https://www.uniprot.org/uniprotkb/Q9W0L6" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W0L6", "url": "https://www.uniprot.org/uniprotkb/Q9W0L6" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W0L6", "url": "https://www.uniprot.org/uniprotkb/Q9W0L6" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W0L6", "url": "https://www.uniprot.org/uniprotkb/Q9W0L6" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W0L6", "url": "https://www.uniprot.org/uniprotkb/Q9W0L6" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W0L6", "url": "https://www.uniprot.org/uniprotkb/Q9W0L6" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W0L6", "url": "https://www.uniprot.org/uniprotkb/Q9W0L6" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG13907", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG13907", "resource": "KEGG Pathway" }, { "id": "R-DME-210991", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-210991", "resource": "Reactome", "description": "Basigin interactions" }, { "id": "R-DME-433692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-433692", "resource": "Reactome", "description": "Proton-coupled monocarboxylate transport" }, { "id": "R-DME-9749641", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9749641", "resource": "Reactome", "description": "Aspirin ADME" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0B4LFF4-1", "protein_name": "Tarag, isoform D", "gene_name": "Targ", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSRNRRRSFPSSQYEDKTAAAQPSGSSLRSQSLSRLDISVQNSSIYYNDTRNTRPQMVSVAVGTVSTDILNGRTSFLSLSQSHGSEVDLPSFYESFNPTFLPKLPIRRFPHMLVGASNEPEISKNQPAIPPSRPIEPISEVPFVEPAFEKKYSRTRGFSKELSTHRDNENEYIESTDEVSQMLSFTSYTDEYDRAEPLITKTQKFYKKRSPLIPKYDSEDSYVVPKETDQQESGLSFNVTTVQLADTASPESFSEYDGNRTRKQSFDMESKNSKESFDFSRGGRRLGSGMVFIYMVIPPDGGFGWVIMVLSFLAQLIIDGLIFTIGVLLPSIAQDLDVSISSVSFVASVQIGCYFTSGAFSAVLINRFGFRKVAIAGVLCSAVSILASSWSVSLTMLIFFYSVLACAGGITLSMIWASSQLIVGYYFERYRPMANGFSCSGGGAGIVLFTFLNSWLVPIIGWRNMLRTQAGLIMLILLMVVAYVEVAPTQVGMYHLPGSSDTSSDEYYGNFYVHDYLRQSAMTAKSRSILSTYEPRPKKKGCAKFCPSCSNCCWRRRKKSQNADEQNLLIRPAPLEREDLFYTGPAEYEKPHSKENVDGKEFLLMGSDKNTQQVNYGIKNIRVDDEPDRISRVHRERRWSNENQKKQNSCRNSRFMLTVLKLFDYRLLKQFEFKILVASAFLFPMGFNIPFVYSSARTTIPVEYARMIGPIIGISNLVMRNILGILAYKRRSWTLGLCGCGLIFGGVSVLISAFYGENLIWFQFLYGFSYAVAPAVYSTLRGLIYVKYLGLSKLTNAFGITSLAMGMGAFIGTTIAGKLIGITGNYSAAFCFAGLCLIVSGFLKLLLPLLIKCRNRMAQ", "length": 859 }, "evidence": [ { "id": "MGI:2385183", "url": "https://alliancegenome.org/gene/MGI:2385183#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070112-602", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070112-602#orthology", "database": "AGR" }, { "id": "HGNC:10925", "url": "https://alliancegenome.org/gene/HGNC:10925#orthology", "database": "AGR" }, { "id": "RGD:1359655", "url": "https://alliancegenome.org/gene/RGD:1359655#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A0A8I6ARJ5-1", "protein_name": "Monocarboxylate transporter 11", "gene_name": "Slc16a11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRGQRAGQGLQPGSSCVRSRRQVRGREPRGAERRGERRGAATRHPHSPQFPIQGWGLCVDNSIPVGLGVRSRPGLGGLAVSRSPALGTHPHPHPVSQVARAPVVISVYRRERSKLGSISALASCSAEPCLPGKRGENSAEPTLALSLPPTPGEVGPGSRAHAPGDVPTLGEQPEAGSQGRQLPSRGPGVETSFTGVSPPQQTAMTPKPAGPPDGGWGWVVAAAAFAVNGLSYGLLRSLGLALPDLAEHFERSAQDTAWVSALALAVQQAASPVGSALSTRWGARPVVMVGGVLTSLGLVFSAFARSLLHLYLGLGLLAGSGWALVFAPALGTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQFLLDTFGWRGALLLLGAVTLHLTPCGALLRPLALSGDPLAPPRTPLAALGLGLFRRPAFSVFALGTALIGGGYFVPYVHLGPHALDQGMGGYGAALVVAVAAVGDASARLVSGWLADQGWVPLPRLLVVFGSLTGLGVLAVGLVPTVGTEEGWGAPLLAAAGAYGLSAGSYAPLVFGVLPGLVGIGGVVQATGLVMMLMSLGGLLGPPLSGFLRDKTGDFSASFLVCSSFILSGSFIYMGLPRALPSCRPASPPATPPPERGELLPVPQVSLLSTGGSSSIRDTTC", "length": 650 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-120907-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120907-2#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M1N837-1", "protein_name": "Monocarboxylate transporter 2", "gene_name": "slc16a7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPPSASTNLGYTPPDGGWGWAVVFGSFISIGFSYAFPKSLTIYFKEIQEYFSISYSQIAWVSSIMLATMYAGGPVSSILVNRYGSRPVVIAGGLMVGVAMVTASFGTSILHLYLCVGVIGGFGLAFNLQPALTIIGKYFLVKRPMANGIAMAGSPVFLSTLAPVNQFLFDQFGWRGSFFILGGVLFNCCVAGSLMRPIKIPVSKTTEDNISPQTAGQDESKPSGCSSKLNQFIDISLFKHRGFLIYLVGNVLMFFGFFAPVVFLAPYAKHQGVDEYSAAFLLSIFALVDMFARPGTGLVANTKWIRPKIQYFFSFAVTYNGLCHLMCPLLPGYIDLVVYAVLFGLAFGMVCALLFEVLMDLVGAQRFSSAVGLATIIECGPVLLGPPISGLLVDIFMDYKYMYFACGMMMLAGGVFLFIMNYYNYRWLKKEEKQRNAEELQIFSTKELAAIDEEIKLSIEEKLKD", "length": 465 }, "evidence": [ { "id": "HGNC:10928", "url": "https://alliancegenome.org/gene/HGNC:10928#orthology", "database": "AGR" }, { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-051113-248", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-051113-248#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1QL69-1", "protein_name": "Monocarboxylate transporter 13", "gene_name": "slc16a13", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEKPQKTEEEQRPCPQGAAPDGGWGWVVVGALFVISALVFGLIRSLGVFFVEFVQYFDESAQAVSWITSIGLAMQQLMSPIGAAASNVYGTRPVVMMGGFLSGLGFILASQATSLLHLYLTMGLISGLGWALVFTPTMASVMQYFTKRRSLAMGLGFTGVGLASFAFSPLFQYLVEAYAWRGALLILGGLSFNMVACGALIRPLGTPKVAVKTENSTKLNKCSFLLSRIYECFELSLLTHRGFVTYAVAITFFNAGYFIPYVHLVAHSRHIGFTEYQAAFVISITGVADIVGRVASGWASDLGKIRLLHMLVVWTGLLGLSLMLIPVAVVYAGLLLVSIVYGFCAGAMAPLAFAVVPEIVGIERVLGALGLLQLIESAGGLLGAPLSGWLKDSTGTYTVSFIAAGSFLMIGMLIAMTLPYFWSCTAPPAPSPSKKKSQEGSAEDGLIGESTSSNAINETLCSGDHIPYSDEEVKVCLSNDATHSVQEQEEIPQEMTHRSNFA", "length": 502 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-120907-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120907-2#orthology", "database": "AGR" }, { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "HGNC:31037", "url": "https://alliancegenome.org/gene/HGNC:31037#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M2BBA0-1", "protein_name": "Monocarboxylate transporter 4-like", "gene_name": "slc16a3a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGGVALDDGGCKVKAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIREFGVGYSDTAWISSILLAMLYGTGPLCSILVNRFGCRPVMLVGGLFASLGMILASFATSIIHIYLCTGVITGLGMALNFQPSLIMLNRYFSEKRPLANGLAAAGSPVALCCLSPLGQVLQYEYGWRGGFLILGGILLNCCACGALMRPLVPPKSSEAPGIENAPDDGDKTVKPKPKLLDFSVFRDRGFLIYTIAASIMVLGLFVPPVFVVSYAKELGNEDTKSALLLSILGFIDIFARPTCGIIAGLQWVRPRCVYLFSFALIFNGITDLVGSLSKDYTSLVVFCIFFGISYGMVGALQFEVLMAVVGTEKFSSAIGLVLMLEAIAVLVGPPSAGRLLDHTKKYMFVFLLAGIEVVLSALVLAICNFLCIKKKPEAPDAAAVESGEPVEEKNHSSPPATEEPHTPNGNSEKPKTDLRPENVTEEPTEEETFLKEEDEKEKTITCSAESDL", "length": 501 }, "evidence": [ { "id": "RGD:620603", "url": "https://alliancegenome.org/gene/RGD:620603#orthology", "database": "AGR" }, { "id": "HGNC:10924", "url": "https://alliancegenome.org/gene/HGNC:10924#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9P097-1", "protein_name": "Monocarboxylate transporter 9", "gene_name": "slc16a9a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAAVKSESTLDGGWGWMIVVASFMAQFLSFGSPQSVGVLYPEWLSAFQEGKGMTAWVGSMVSGVALITSPVCSACVDNFGARPVTIFSGVMVAGGLMLSAFAPNISFLIFSYGIVVGMGCGLVYAATLTITCQYFDKRRGLALGIVTTGTSVGGFIYATLQNELIELFGLEGCLLIIGALALNLMACAGPMRPLNLPGYYLKQRAALQRTEDPEPLYSKPTAIIIESGSDLKTKPGLAENTTTVKLLINKDPTELQDSEGERKVHILSSSIIARAIKKWMRPYGQYFCETVELLQDRVFMAFCIAMFLFSLGAFPPVLFMEDVAQSEGLIDGIALIPLVSIVAMTTGIGKLILGVLADMRWVNSLYLYALTLIGSGTALLLIPVSKSYLGLQILSAAVGFFSGNWSLTSYITTKIVGIERLGQAHGILMCFGGFGIALGPPVVGWFFDWTQSYDLAFYLSGTCVLVSGVFLFLAALPCWNRTAQEGNSQAEEDVNTSQQHHSFDCDKVASVA", "length": 512 }, "evidence": [ { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PFG6-1", "protein_name": "Monocarboxylate transporter 13", "gene_name": "si:dkey-246g23.4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MERKRGTAGPAGPPLDGGYGWFIVLSTFLVFGLTFGVIKSFGVFFVEIHHYFSTTATASSWITSISVATVHIGAPVGSALSTYFGHRPVVMAGGLLSSVGMVLGSFAQDLLQLYITVGFLTGFGYALTWTPTVTMLGWYFDKRRPVANALSSTGECLLTFILTPSFQLMVDQFSWRGAMLILGALQLNLCVCGALLRPLSRHDYFKDSIEENEHELSKCSNNRADSDPMKVKVIRYVDYTLIANSRFMVYSMFGIFAALGFFAPSLFLVPYARSQGVEEYQAASLMSISAVLDLLGRVFFGWVANLRLVETVHQLIGTVVLLGAVLLLCPLATTFTQLAVFSAGYGLVFGATVAIHITVLAEVVGVERLGSALGFFMLIRSSGGLLGPPLAGIFIDKMSDYGAGFLMAGVALLVSALFLIVLHFMNKKETEHKKDICSENEEEHEDLKNRNFVFGKS", "length": 457 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050419-234", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-234#orthology", "database": "AGR" }, { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9QAK1-1", "protein_name": "Monocarboxylate transporter 6", "gene_name": "slc16a5b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTEGVEVHQPQPNTTVTRSRASSLQAFENADTASCKSEEPDQEEEEEQSSSTLPEERHCSTGGQANAQLAPDGGWGWVVVAATILVLAMTLAFPSCIGIFYTELQSDFQASNTETSWVPAIMMAVLHACGPICSVLVERCGCRATIIIGGILSGLGMAASSFAQTMVELYITAGIITGMGFSLCFQPSITMVGHYFVRRRAFANALSSTGTALGLSILPLLANYLLRNFGWRGSFLVLGGVLLNCCVCGAVMRPLAAKPKMETRTKETDNHHLKTNCLSVHQGLKGRLRATLSTIMTFLRRHMAFDLLCSNPYFCAYALGVSWMMLGFVVPLVYLVPYATAYGMEQDQAALLMAILGLINIIVRPATALVFGLPRFRGSHNFAYLFAIAVVINGLSNCVCGIGTSFLVLLVYVILFGFSMSLVGSLLFTVLMDTVEMSRFPSALGLISIMESIMLLLGPPLAGILVDSTGQYIYVFFACSVTGSTAGLFIMLSFYWLDRRRDREQVKSSSAHQDPHSLKPSLKMTIDCEYSPVPLHSKNTRDTETDV", "length": 547 }, "evidence": [ { "id": "MGI:2443515", "url": "https://alliancegenome.org/gene/MGI:2443515#orthology", "database": "AGR" }, { "id": "HGNC:10926", "url": "https://alliancegenome.org/gene/HGNC:10926#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131120-181", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131120-181#orthology", "database": "AGR" }, { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "RGD:1582896", "url": "https://alliancegenome.org/gene/RGD:1582896#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABK0LFB5-1", "protein_name": "Solute carrier family 16, member 4", "gene_name": "Slc16a4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKREEKPSPYTKPLDGGWGWMVVLHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIGWIGSIMSSLRFSAGPLAAIICDIFGEKTTSILGTFLVSGGYLISSWATGIPFLCVTMGLLPGLGSAFLYQVAAVVITKYFKKRLGLSTAIARSGMGLTFLLAPFTKLLIDLYDWTGALILFGAIALNLVPSSMLLRPVHIQSDSNSDIKNKGSILSATGPELSHKTETPNRNKAQESLIKDSAVKKSGQPTTTLTVLENQIEEISTRPHRNRPLLMSNDKTYKKKFVSWNCKEKLLDISLFRNPFFYIFTWSFLLSQLAYFIPTFHLVARAKTLGIDIMDASYLVSVAGITETVSQLISGWIADQNWIKKYQYHKAYLILCGVTNLLAPLATTFPLLMAYTIFFAIFAGGYLALILPVLVDLSKNSRVHRFLGYASFFAGMAVLSGPPIAGSHVTYAGLKLTTLEDAGFELLILLCLSPKCWNYRHVPPFLASISFPIFFNEKE", "length": 504 }, "evidence": [ { "id": "MGI:2385183", "url": "https://alliancegenome.org/gene/MGI:2385183#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070112-602", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070112-602#orthology", "database": "AGR" }, { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "HGNC:10925", "url": "https://alliancegenome.org/gene/HGNC:10925#orthology", "database": "AGR" }, { "id": "RGD:1359655", "url": "https://alliancegenome.org/gene/RGD:1359655#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ACD6B5K3-1", "protein_name": "Monocarboxylate transporter 3 isoform X1", "gene_name": "slc16a8", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGGIVEDRETAGAPDGGWGWVVLLGGFVITGFSYAFPKAISVYFKELMHDFGCGYKDTAWISSIILAMLYGSGPISSIMVNKFGCRPVMLVGGLLASLGMISASFATSIIHLYITAGVITGLGLALNFQPSLIMLGAYFDKRRPLANGLAAAGSPVFLSALSPLGQLLLDQYGWRGGFLITGGLLLNCCTCGAVMRPLKLKERKACNQELKEMLPPEAGQENIVCENNNDKKPSKKKLLDFSVLRDKGLIIYIIAKFIVVLGLFVPTILLVNYAKDQGVPDKEAAFLLSIIGFIDIFARPTCGVVAGLKWVRPKMSYFFSLALLFNGLTDVCSATSTDYKGLIIFCVFFGLSYGMVGALQFEVLMGIVGTSKFSSALGLVLLFEAVAVLIGPPSAGYLVDKYKNYELIFYMAGGELITAGIFLALASFCCISQKKRKDSPQTQQTYVEVNPER", "length": 453 }, "evidence": [ { "id": "MGI:1929519", "url": "https://alliancegenome.org/gene/MGI:1929519#orthology", "database": "AGR" }, { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121128-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121128-1#orthology", "database": "AGR" }, { "id": "RGD:69282", "url": "https://alliancegenome.org/gene/RGD:69282#orthology", "database": "AGR" }, { "id": "HGNC:16270", "url": "https://alliancegenome.org/gene/HGNC:16270#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A1L1W9-1", "protein_name": "Monocarboxylate transporter 10", "gene_name": "slc16a10", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTEPEPTLEQEPTPEPEPTQEPTPEPTPEPEPTQEPESEPELELKQENGCTKASEQKSPEEFEPPEGGWGWVVMLASMWCNGSVFGIQNAFGIMFVYLLNEFGSEHDADLRFKTAWVGSLSMGMIFFCSPIVSVFTDLLGCRITAVGGAAVGCVGLLASSFVTSLGPMYFTYGIVFACGCSFAYQPSLVILGHYFKRRLGLVNGIVTAGSSVFTITLPYMLSGLLKSVGLYHTLRVLAIFMFILMLAGLTYKPLLPKPVSSSKPGSRCPPLSRIFNVNIWKSLGYRIWAFGIPAALYGYFVPYVHLMTHVEERFGPEANKEVLLACIGITSGVGRLIFGRVADYVPGVNKVFLQVSSFMVIGVMSMMIPLCHVFGGLIAVCLLMGLFDGCFICIMAPIAFELVGSQNVSQAIGFLLGMMSIPMTVGPPIAGFLRDRLGSYDVAFYLAGIPPLIGGAVLCAIPWVEARRKRREAANTAENTEKMLESRSPPLEDTVCRTEEPESVI", "length": 505 }, "evidence": [ { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "B1AT66-1", "protein_name": "Monocarboxylate transporter 7", "gene_name": "Slc16a6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRASGQGPQRRRRGWATRDDSAVTFRDPQPRQPAGGARALRGPDPRGPARAHQAGPLLAGARRSQHMVGGAPPRPAETGCSRSRMTQKNSKLCARANVYTQVPDGGWGWAVAVSFFFVEVFTYGIIKSFGVFFNDLMDSFDESNSKISWIISICVFVLTFTAPLSTVLSNRFGHRLVVMAGGLLISLGMITASFSQRVYHMYISIGVISGLGYCFSFLPTVTILSQYFDKRRSVVTAVASTGECFAVFAFAPAITALKEHIGWRYSLLFVGLLQLNIMVCGALLRPIIIQGPGQSPKAVTLEPRREVQYMLENEKTRTSIDSIDSGVELTTSPKNVPSEAKMEQETRAEQQQTLVTAPKHSQMKAPLLDFSVLKEKSFICYALFGLFATLGFFAPSLYIIPLGISLGIDPDRAAFLLSTMAIAEVFGRIGAGFVLNREPIRKIYIELICVILLTASLFAFTFATEFWGLMLCSVFFGSMVGTIGGTHIPMLAEDDVVGIEKMSSAAGVYVFIQSISGLAGPPLAGLLVDQSKIYSRAFYSCAAGMCLAAVCLALVRPCKKGLCQNSHSGENQTDRQRGKALQDIPEDFLEMDLGKCEHRAHMKMDPV", "length": 607 }, "evidence": [ { "id": "RGD:735117", "url": "https://alliancegenome.org/gene/RGD:735117#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D4A0E5-1", "protein_name": "Monocarboxylate transporter 14", "gene_name": "Slc16a14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYTSHEDIGYDLEDDRKAKNKKTLKPHPDIDGGWAWMMVLSSFFVHILIMGSQMALGVLNVEWLEEFHQSRGLTAWVSSLSMGITLIVGPFIGLFINTCGCRQTAIIGGLVNSLGWVLSAYAANVQSLFITFGVAAGLGSGMAYLPAVVMVGRYFQKRRALAQGLSTTGTGFGTFLMTVLLKYLCAEYGWRNAMFIQGALSLNLCVCGALMRPLSPEKVENCSGAEEPCALPAYSTESVKSGGPLDMTEEQDRRPGNEETVCDLQTQELQGQTHPRKNVCAFRVLKTVGQLTVRVQRGFRDWHSGYFGTASLFTNRMFVAFIFWALFAYSSFVIPFIHLPEIVSLYNLSEQNDAFPLTSIIAILHIFGKVILGAVADLPCISVWNVFLIANFTLVLSIFLLPLMHTYASLAVICALIGFSSGYFSLMPVVTEDLVGTEHLANAYGIIICANGISALLGPPFAGWIFDITQKYDFSFYICGLLYMVGILFLLIQPCIQMTEQSGRKCMDSAHV", "length": 512 }, "evidence": [ { "id": "HGNC:26417", "url": "https://alliancegenome.org/gene/HGNC:26417#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A3B5-1", "protein_name": "Monocarboxylate transporter 6", "gene_name": "Slc16a5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPQALEQADGRWAWVVLLASLVTQALTVGFPSCIGVFFTDLQRDFQASNSETSWFPSIMGAMLHCGGPLCSILIKRFGCRVTMMLGGVLASLGMVASTFSDSLIHLFLTAGLITGLGMCFSFQSSITVVGLYFVRQRPLANALASIGISMGVTLWPLLARYLLETLGWRGAFLIFGGIFLHCCVCGAMLRPVATNVDPEPKEDLLLPPKTPTRSCLATCVSTIQYYLAFDILRHNMVFCIYVTGATWMTLGFSLPHIFLVPYAMHHGMEEYWAAMLMSIVGFCNIFLRPVAGMLAGRKSLAAYRKYLFAVAILINGLTNLICTVSADFRVLLGYCLVYSLSMCGTGILVFQVLMDIVPMDRFPSALGLFTILCGMGSLISPPLAGLLLDTTNNFNYVFYMSSGLLISASLFMGVGFYVAEKKLKQDRQAKMEDATSEITSKHSLTSEDKDSAKKQPYPENIYVTSV", "length": 466 }, "evidence": [ { "id": "MGI:2443515", "url": "https://alliancegenome.org/gene/MGI:2443515#orthology", "database": "AGR" }, { "id": "HGNC:10926", "url": "https://alliancegenome.org/gene/HGNC:10926#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131120-181", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131120-181#orthology", "database": "AGR" }, { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121108-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121108-4#orthology", "database": "AGR" }, { "id": "RGD:1582896", "url": "https://alliancegenome.org/gene/RGD:1582896#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A734-1", "protein_name": "Monocarboxylate transporter 12", "gene_name": "Slc16a12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKITRVGSASPPDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFAQDYSQTAWIHSIVDCMTMLCAPLGSVVSNQLSCQAGIMLGGLLASTGLILGSFATSLKHLYLSLGVLTGLGFALCYSPAIAMVGKYFSRRKAFAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCGALMRPITLKEDPSGPEKSHDRDAQREDCKQASPYSPLTKEWTETRLCCSLQQGYGFLLMSDFVVLAVSVLFMAYGCSPLFVYLVPYALSVGVSHHQAAFLMSILGVIDIVGNITFGWLTDRRCLKNYRYVCYLFAVALDGLCYLCLPMLQSFPLLVPFSCTFGYFDGAYVTLIPVVTAEIVGTTSLSSALGVVYFLHAVPYLVSPPIAGWLVDTTGSYTAAFLLCGFAMIFSSILLGFAKIAKRMKRTQVPFLVKDSDPKLHLWTNGSVAYSIAKELDQKDEESLAKARTGCNLT", "length": 486 }, "evidence": [ { "id": "MGI:2147716", "url": "https://alliancegenome.org/gene/MGI:2147716#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7F7B3-1", "protein_name": "Monocarboxylate transporter 1", "gene_name": "slc16a1a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAPAVGGPVGYTPPEGGWGWAVVLGAFISIGFSYAFPKSITVFFKEIEVIFNATSSQVSWISSIMLAVMYGGGPVSSILVNKYGSRPIMILGGCLSGAGLIAASFCNTVEGLYFCVGVVGGLGLAFNLNPALTMIGKYFYKKRPIANGIAMAGSPVFLSTLAPLNTWFFDQFGWRGSFLILGGLLLNCCVAGSLMRPIGPKPQPAVKADNSNSRAKERKTVVEVINGFIDLTLFKHRGFLLYLLGNVVMFFGLFSPLVFLSNYAKSKQIPREKAAFLLSILAFVDMVARPSMGIVANTKWVRPRVQHFFAASILLNGVCHLLAPLSTDYTGFVIYAIFFGFAFGWLSSVLFETLMDLVGAQRFSSAVGLVTIVECGPVLLGPPLLGKFNDIYHDYKYTYMGCGIVLLIGSLFLFVGMGINYKLLEREAKEESKKANQQDDPGKEVVEALKAAEDNAAEEAV", "length": 461 }, "evidence": [ { "id": "MGI:106013", "url": "https://alliancegenome.org/gene/MGI:106013#orthology", "database": "AGR" }, { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "RGD:3690", "url": "https://alliancegenome.org/gene/RGD:3690#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110408-16", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110408-16#orthology", "database": "AGR" }, { "id": "HGNC:10922", "url": "https://alliancegenome.org/gene/HGNC:10922#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FB53-1", "protein_name": "Monocarboxylate transporter 6", "gene_name": "slc16a5a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAPQQPSSMEEQSGELCEPESEELEKQGPGPPSNANAPDSYDAPDGGWGWVVLLATIIVLALTLAFPSCIIIFYLDLQKEFEATNSQTSWVPSIMTAVLHAGGPLCSVLVDRFGCRATVMFGGVLSGFGMAVSSFSHSIVDLYITAGVITGLGFCFSFQPAVTILGHYFVRRRPFANAMSSTGTALGLSTLPFLCDFLKIELGWRGSFLVLGAVLLNCCVCGAVMRPIRPRKPRKTNEINNSPKTSDKKGCMLGICQSLASSLRQQMAFDLFCSNTRFRVFSLGITWMMLGFVVPLIYLVPYASADDMDPSRAALLLSILGFVNIFVRPPVGVLFSLPWFKGRHIYVFSAALLINGLSNSICCISASFPVLLVYVLTYGLSMSVVGSLMFTVLMDTVEMSRFPSALGLLSIMESVTLLIGPPLAGFLVDRTQLYTYVFMACTIIVVLSALFLMFTFYWLDSRDAAKKDSPAKPAINISTDCQYSSVPIDGDKTNKPSSETENTTCV", "length": 506 }, "evidence": [ { "id": "MGI:2443515", "url": "https://alliancegenome.org/gene/MGI:2443515#orthology", "database": "AGR" }, { "id": "HGNC:10926", "url": "https://alliancegenome.org/gene/HGNC:10926#orthology", "database": "AGR" }, { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121108-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121108-4#orthology", "database": "AGR" }, { "id": "RGD:1582896", "url": "https://alliancegenome.org/gene/RGD:1582896#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1Q7T3-1", "protein_name": "Monocarboxylate transporter 4 isoform X1", "gene_name": "slc16a3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGGAVVDTGDSGVKAPDGGWGWAVLFGCFIITGFSYAFPKAVSVFFKELIREFGVGYSDTAWISSILLAMLYGTGPLCSILVNRFGCRPVMMVGGLFASLGMVLASFATNIIHIYLCTGVITGLGLALNFQPSLIMLNRYFSEKRPLANGLAAAGSPVALCCLSPLGQVLQYKYGWRGGFLILGGLLLNCCACGALMRPLLAPKKTSEVEEKPKETKPKPKLLDFTVFKDRGFLIYTIAASIMVLGLFVPPVFVVSYAKELGNEDTKSALLLTILGFIDIFARPTSGIIAGLKWVRPRCVYLFSFAMIFNGIADILGSFAKDYASLVVFCIFFGISYGMVGALQFEVLMAIVGTEKFSSAIGLVLLVEAIAVLVGPPGAGRLLDATKNYMYVFMLAGCEVVLSALVLAICNLLFIKRKPQQPDPPAKMEMAITETEMEELNKAPKDDQDNGGGAENEKKQAIEPETKTTSKDEVKELESIEVDSIEVENASKKVSGPNGVAVEPESSL", "length": 508 }, "evidence": [ { "id": "RGD:620603", "url": "https://alliancegenome.org/gene/RGD:620603#orthology", "database": "AGR" }, { "id": "HGNC:10924", "url": "https://alliancegenome.org/gene/HGNC:10924#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QW16-1", "protein_name": "Monocarboxylate transporter 5", "gene_name": "slc16a4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLPKEQHSDGKTAKTPCSELKAKVMKKEKKKVVYREPPDGGWGWMVVLHCFLVNVLVMGTLKTFGIFFVALQDEFGGSSESISWIGSIMSSLRLSGGPLASVACAKLGNRVTSIVGALFVSAGFLFSIFATSVTYLYISMGLVVGLGFALLYQATSVVIVTYFRKRLATAYSIGRSGMGLTFALAPFTQLLLDQYAWQGALLILGGLMLNLVASGMLLRPINIRHPASPISNSTIHKTEKDPLKNNMNGNTPVANGTSKSDSSPPIHKDTLIIKNPVHEQNSLPHLDLKKPTQNGVNGTDSSQTKTSPEMNGVSPVDSLLENGRTENVPENSPKVLDFSLLKNPFFCIYTWSLVFSQLAYFIPYFHLSARARNLGIDPMDASFIISVAGITETVAQLASGWVTDRNLVHKYHYHKAYLILCGVVNLLSPLATSYILLMVYAVFFAIFCGGYMALLLPVLVDLVGADKLNNSMGFSMFFVGLGCLTGPPLAGFLYDYTQTYDCSFYLAGVCYLLSSISLFLEPLARRWQARKERLETLNQELMWSNGCFCPAPQRNGVV", "length": 558 }, "evidence": [ { "id": "MGI:2385183", "url": "https://alliancegenome.org/gene/MGI:2385183#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070112-602", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070112-602#orthology", "database": "AGR" }, { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "HGNC:10925", "url": "https://alliancegenome.org/gene/HGNC:10925#orthology", "database": "AGR" }, { "id": "RGD:1359655", "url": "https://alliancegenome.org/gene/RGD:1359655#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G5E8K6-1", "protein_name": "Monocarboxylate transporter 6", "gene_name": "Slc16a5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARALEQADGRWAWVVLLSSLVTQALTLGFPTCIGVFFTDLQRDFQASNSETSWFPSILGAMVHGGGPLCSILVKHFGCRVTMMLGGVLASLGMVVSTFSGSLTHLFLTAGVITGLGMCFSFQSSITVVGLYFVRRRPLANALASMGLSMGVTLWPLLARYLLETLGWRGAFLIFGGILLHCCVCGALLRPVATNEVPEPKEDPLLPPKIPTRSCLATCVSTIRYHLAFDILRHNMGFCIYVTGVTWMNLGFALPHIFLVPYAMHHGVDDYWAAMLMSIVGFCNIFLRPMAGLLLAGRKSLAAYRKYLFAVAILINGLTNLICTVSADFRVLLGYCLVYSLSMCGVGILVFQVLMDIVPMDRFPSALGLFTILCGVTSLISPPLAGLLLDKTNNFSYVFYMSSGFLVSGSLILGVGFYAAEKKKLKQDGQAKMENATSEMTPMHDLTSEDKDSAKKQPYPESIYMTNV", "length": 468 }, "evidence": [ { "id": "MGI:2443515", "url": "https://alliancegenome.org/gene/MGI:2443515#orthology", "database": "AGR" }, { "id": "HGNC:10926", "url": "https://alliancegenome.org/gene/HGNC:10926#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131120-181", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131120-181#orthology", "database": "AGR" }, { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121108-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121108-4#orthology", "database": "AGR" }, { "id": "RGD:1582896", "url": "https://alliancegenome.org/gene/RGD:1582896#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G8XYX6-1", "protein_name": "Monocarboxylate transporter 8", "gene_name": "slc16a2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MHSESDDNTAGGTPGSEDPQAEESSSPAEEFEEQERKLAPEDSTVQLIHTGCTDKRPATPPGAHPGQGFVPPEGGFGWVVVFAATWCNGSIFGIQNSFGILHMMLVKHHEKQPDQASQFKVAWVGALAMGMIFFCSPVVSMFTDHFGCRKTAVCGAFVAFIGLLTSSFATTLGLWYFTYGILFGCGSSFAFQPSLVILGHYFRQRLGLANGVVTAGSSLFSMGLPVLLKKVVEPLGLPRTFQILSIFMLVQALLALAFKPLLPSGMCPMPGMALDGGPSTPESASRWQKGLAKIRRYFNVRVFSILTYRIWAFGVATAVLGYFVPYVHLLNFVKEQFGDTQREWLLLVCIGASSGVGRLLFGKIGDLIPGVKKIYMQVASFILLGVMSMMIPQCAVFEGLVVVFVLMGLCDGCFITIMAPIAFELVGPMQASQAIGYLLGLMAIPMTAGPPIAGLLHDHFGNYHVAFYLAGVPPIVGGIVMFFVPLVHQRMQKRRKETDDPSMDKMLKNCSNGDMLPGYTDMETHI", "length": 526 }, "evidence": [ { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "M0RCI4-1", "protein_name": "Monocarboxylate transporter 9", "gene_name": "Slc16a9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGFQKSPDGGWGWVIVVVSFFTQFLCYGSPLAVGVLYVEWLDAFGEGKGKTAWVGSLASGVGLLASPVCSLFVSSFGARPVTIFSGFLVAGGLMLSSLAPNIYFLFFSYGIVVGLGCGLLYTATVTITCQYFDSRRGLALGLISTGSSVGLFIYAALQRMLIEFYGLDGCLLIVGALALNILACGSLMRPLQTSDCPFPEKIAPENVPDRYSIYNEKEKNQEETMTFQDKGYSNEDKCLPNGDWGRETSLPKNPTGAAHTKEPEPYKKKVVEQTNFCKQLAKRKWQVYRNYCGETASLFKNKVFSALFVAILLFDIGGFPPSLLMEDVARSYHVREEDLTIPLISIFGIMTAVGKLLLGILADFKWVNTLYLYVATLIITGLALCAIPLAKSYVTLAILSGILGFLTGNWSIFPYVTTKTVGIDKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGFCVLLGGFILLLAILPCWGMCNQRLPKPAAPTTFFYKVASNV", "length": 508 }, "evidence": [ { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O15374-1", "protein_name": "Probable monocarboxylate transporter 5", "gene_name": "SLC16A4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLKREGKVQPYTKTLDGGWGWMIVIHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIGWIGSIMSSLRFCAGPLVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLLPGLGSAFLYQVAAVVTTKYFKKRLALSTAIARSGMGLTFLLAPFTKFLIDLYDWTGALILFGAIALNLVPSSMLLRPIHIKSENNSGIKDKGSSLSAHGPEAHATETHCHETEESTIKDSTTQKAGLPSKNLTVSQNQSEEFYNGPNRNRLLLKSDEESDKVISWSCKQLFDISLFRNPFFYIFTWSFLLSQLAYFIPTFHLVARAKTLGIDIMDASYLVSVAGILETVSQIISGWVADQNWIKKYHYHKSYLILCGITNLLAPLATTFPLLMTYTICFAIFAGGYLALILPVLVDLCRNSTVNRFLGLASFFAGMAVLSGPPIAGWLYDYTQTYNGSFYFSGICYLLSSVSFFFVPLAERWKNSLT", "length": 487 }, "evidence": [ { "id": "MGI:2385183", "url": "https://alliancegenome.org/gene/MGI:2385183#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070112-602", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070112-602#orthology", "database": "AGR" }, { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "HGNC:10925", "url": "https://alliancegenome.org/gene/HGNC:10925#orthology", "database": "AGR" }, { "id": "RGD:1359655", "url": "https://alliancegenome.org/gene/RGD:1359655#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O15375-1", "protein_name": "Monocarboxylate transporter 6", "gene_name": "SLC16A5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPQALERADGSWAWVVLLATMVTQGLTLGFPTCIGIFFTELQWEFQASNSETSWFPSILTAVLHMAGPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQSSITVLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGAIIRPVATSVAPETKECPPPPPETPALGCLAACGRTIQRHLAFDILRHNTGYCVYILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAGLMAGRPAFASHRKYLFSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIFQVLMDIVPMDQFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSFFLISAALFMGGSFYALQKKEQGKQAVAADALERDLFLEAKDGPGKQRSPEIMCQSSRQPRPAGVNKHLWGCPASSRTSHEWLLWPKAVLQAKQTALGWNSPT", "length": 505 }, "evidence": [ { "id": "MGI:2443515", "url": "https://alliancegenome.org/gene/MGI:2443515#orthology", "database": "AGR" }, { "id": "HGNC:10926", "url": "https://alliancegenome.org/gene/HGNC:10926#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131120-181", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131120-181#orthology", "database": "AGR" }, { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121108-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121108-4#orthology", "database": "AGR" }, { "id": "RGD:1582896", "url": "https://alliancegenome.org/gene/RGD:1582896#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O15403-1", "protein_name": "Monocarboxylate transporter 7", "gene_name": "SLC16A6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTQNKLKLCSKANVYTEVPDGGWGWAVAVSFFFVEVFTYGIIKTFGVFFNDLMDSFNESNSRISWIISICVFVLTFSAPLATVLSNRFGHRLVVMLGGLLVSTGMVAASFSQEVSHMYVAIGIISGLGYCFSFLPTVTILSQYFGKRRSIVTAVASTGECFAVFAFAPAIMALKERIGWRYSLLFVGLLQLNIVIFGALLRPIFIRGPASPKIVIQENRKEAQYMLENEKTRTSIDSIDSGVELTTSPKNVPTHTNLELEPKADMQQVLVKTSPRPSEKKAPLLDFSILKEKSFICYALFGLFATLGFFAPSLYIIPLGISLGIDQDRAAFLLSTMAIAEVFGRIGAGFVLNREPIRKIYIELICVILLTVSLFAFTFATEFWGLMSCSIFFGFMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYIFIQSIAGLAGPPLAGLLVDQSKIYSRAFYSCAAGMALAAVCLALVRPCKMGLCQHHHSGETKVVSHRGKTLQDIPEDFLEMDLAKNEHRVHVQMEPV", "length": 523 }, "evidence": [ { "id": "RGD:735117", "url": "https://alliancegenome.org/gene/RGD:735117#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O15427-1", "protein_name": "Monocarboxylate transporter 4", "gene_name": "SLC16A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGGAVVDEGPTGVKAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDTAWISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALNFQPSLIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLNCCVCAALMRPLVVTAQPGSGPPRPSRRLLDLSVFRDRGFVLYAVAASVMVLGLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGFVAGLGKVRPYSVYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTHKFSSAIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSSLILLLGNFFCIRKKPKEPQPEVAAAEEEKLHKPPADSGVDLREVEHFLKAEPEKNGEVVHTPETSV", "length": 465 }, "evidence": [ { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "RGD:620603", "url": "https://alliancegenome.org/gene/RGD:620603#orthology", "database": "AGR" }, { "id": "HGNC:10924", "url": "https://alliancegenome.org/gene/HGNC:10924#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O35308-1", "protein_name": "Monocarboxylate transporter 3", "gene_name": "Slc16a8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGAGGPRRGAGPPDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRELKRDFGAGYSDTAWVSSIMLAMLYGTGPLSSILVTRFGCRPVMLAGGLLASAGMILASFASRLVELYLTAGVLTGLGLALNFQPSLIMLGLYFERRRPLANGLAAAGSPVFLSMLSPLGQLLGERFGWRGGFLLFGGLLLHCCACGAVMRPPPGPPPRRDPSPHGGPARRRRLLDVAVCTDRAFVVYVVTKFLMALGLFVPAILLVNYAKDAGVPDAEAAFLLSIVGFVDIVARPACGALAGLGRLRPHVPYLFSLALLANGLTDLISARARSYGTLVAFCIAFGLSYGMVGALQFEVLMATVGAPRFPSALGLVLLVEAVAVLIGPPSAGRLVDALKNYEIIFYLAGSEVALAGVFMAVTTYCCLRCSKNISSGRSAEGGASDPEDVEAERDSEPMPASTEEPGSLEALEVLSPRAGSPEQEPEEEAVPELDHESIGGHEARGQKA", "length": 492 }, "evidence": [ { "id": "MGI:1929519", "url": "https://alliancegenome.org/gene/MGI:1929519#orthology", "database": "AGR" }, { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121128-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121128-1#orthology", "database": "AGR" }, { "id": "RGD:69282", "url": "https://alliancegenome.org/gene/RGD:69282#orthology", "database": "AGR" }, { "id": "HGNC:16270", "url": "https://alliancegenome.org/gene/HGNC:16270#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O35910-1", "protein_name": "Monocarboxylate transporter 4", "gene_name": "Slc16a3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGGAVVDEGPTGIKAPDGGWGWAVLFGCFIITGFSYAFPKAVSVFFKELMHEFGIGYSDTAWISSILLAMLYGTGPLCSMCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQIYLTTGVITGLGLALNFQPSLIMLNRYFNKRRPMANGLAAAGSPVFLCALSPLGQLLQDHYGWRGGFLILGGLLLNCCVCAALMRPLVAPQASGGAEPHGPQRPSPRLLDLSVFRDRGFLIYAVAASIMVLGLFVPPVFVVSYAKDMGVPDTKAAFLLTILGFIDIFARPTAGFITGLKKVRPYSVYLFSFAMFFNGFTDLTGSTASDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTQKFSSAIGLVLLLEAVAVLIGPPSGGKLLDATKVYKYVFILAGAEVLTSSLVLLLGNFFCIGKRKRPEVTKPEEVASEEEKLHKPPVDVRVDSREVEHFLKAEPEKNGEVVHTPETSV", "length": 471 }, "evidence": [ { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "RGD:620603", "url": "https://alliancegenome.org/gene/RGD:620603#orthology", "database": "AGR" }, { "id": "HGNC:10924", "url": "https://alliancegenome.org/gene/HGNC:10924#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O60669-1", "protein_name": "Monocarboxylate transporter 2", "gene_name": "SLC16A7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPPMPSAPPVHPPPDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAWISSIMLAVMYAGGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPALTIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLILGSLLLNACVAGSLMRPLGPNQTTSKSKNKTGKTEDDSSPKKIKTKKSTWEKVNKYLDFSLFKHRGFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAFVDMFARPSVGLIANSKYIRPRIQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGSVSSVLFETLMDLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCGAIVVAASVWLLIGNAINYRLLAKERKEENARQKTRESEPLSKSKHSEDVNVKVSNAQSVTSERETNI", "length": 478 }, "evidence": [ { "id": "MGI:1330284", "url": "https://alliancegenome.org/gene/MGI:1330284#orthology", "database": "AGR" }, { "id": "HGNC:10928", "url": "https://alliancegenome.org/gene/HGNC:10928#orthology", "database": "AGR" }, { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "RGD:3691", "url": "https://alliancegenome.org/gene/RGD:3691#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-051113-248", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-051113-248#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O70324-1", "protein_name": "Monocarboxylate transporter 8", "gene_name": "Slc16a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALPSPASEEAEGPCQEANQEYQEPVCSPVPEPEPEPEPEPEPDPEPVPVPPPEPQPEPEPQPLPDPAPLPELGFEAEPVQEPEPTPTVETRGTARGFQPPEGGFGWIVVFAATWCNGSIFGIHNSVGILYSMLLEEEKEKNRQVEFQAAWVGALAMGMIFFCSPIVSIFTDRLGCRITATTGAAVAFIGLHTSSFTSSLSLRYFTYGILFGCGCSFAFQPSLVILGHYFQRRLGLANGVVSAGSSIFSMSFPFLIKMLGDKIKLAQTFQVLSTFMFVLTLLSLTYRPLLPSSQDTPSKRGAHTLRQRFLVQFRKYFNMRVFRQRTYRIWAFGIAAAALGYFVPYVHLMKYVEDKFKEIKETWVLLVCIGATSGLGRLVSGHISDSIPGLKKIYLQVLSFLLLGLMSMMIPLCRDFGGLIVVCLFLGLCDGFFITIMAPIAFELVGPMQASQAIGYLLGMMALPMIAGPPIAGLLRNCFGDYHVAFYFAGVPPIIGAVILFFVPLMHQRMFKKEQRDSSKDKMLSHDPDPNGELLPGSPTPEEPI", "length": 545 }, "evidence": [ { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O70451-1", "protein_name": "Monocarboxylate transporter 2", "gene_name": "Slc16a7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPSEPSAPLPQPLPPDGGWGWVVVCASFISIGFSYAFPKAVTVFFKDIQEIFNTTSSQIAWISSIMLAVMYAGGPISSVLVNNYGSRPVVIVGGLLCCIGMILASYSNSVIELYLTVGFIGGLGLAFNLQPALTIIGKYFYRRRPLANGCAMAGSPVFLSTLAPFNQYLFNNYGWKGSFLILGGIFLHSCVAGCLMRPVGPSPNTKKSKSKVGSRHDSTLKKASKVSTAQKVNRFLDFSLFMHRGFLIYLSGNVILFLGIFAPIIFLAQYAKHIGVDDYNSAFLLSVMAFIDMFARPSVGLIANTSLIRPRIQYLFSSAIIFTGICHLLCPLATTYSALVVYVVFFGLGFGSISSLLFECLMDIVGATRFSSAVGLTTIVECCPVLFGPPLAGKLLDITGEYKYLYIASGTVVLVSGTYLLIGNAINYRLLDKERKREKAKKKKSASHASREMEALNRSKQDEVTVKASNAHNPPSDRDKESNI", "length": 484 }, "evidence": [ { "id": "MGI:1330284", "url": "https://alliancegenome.org/gene/MGI:1330284#orthology", "database": "AGR" }, { "id": "HGNC:10928", "url": "https://alliancegenome.org/gene/HGNC:10928#orthology", "database": "AGR" }, { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "RGD:3691", "url": "https://alliancegenome.org/gene/RGD:3691#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O70461-1", "protein_name": "Monocarboxylate transporter 3", "gene_name": "Slc16a8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGAGGPRRGAGPPDGGWGWVVLGACFVITGFAYGFPKAVSVFFRELKRDFGAGYSDTAWVSSIMLAMLYGTGPLSSILVTRFGCRPVMLAGGLLASAGMILASFASRLLELYLTAGVLTGLGLALNFQPSLIMLGLYFERRRPLANGLAAAGSPVFLSTLSPLGQLLGERFGWRGGFLLFGGLLLHCCACGAVMRPPPGPQPRPDPAPPGGRARHRQLLDLAVCTDRTFMVYMVTKFLMALGLFVPAILLVNYAKDAGVPDAEAAFLLSIVGFVDIVARPACGALAGLGRLRPHVPYLFSLALLANGLTDLISARARSYGTLVAFCIAFGLSYGMVGALQFEVLMATVGAPRFPSALGLVLLVEAVAVLIGPPSAGRLVDALKNYEIIFYLAGSEVVLAGVFMAVTTYCCQRCSKDIPPGPSAEGGTSDTEDVEAERDSEPMPASTEEPGSLEALEVLSPRAGSPEPEEEAVPDLSHESVGGHEAHGQNA", "length": 490 }, "evidence": [ { "id": "MGI:1929519", "url": "https://alliancegenome.org/gene/MGI:1929519#orthology", "database": "AGR" }, { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121128-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121128-1#orthology", "database": "AGR" }, { "id": "RGD:69282", "url": "https://alliancegenome.org/gene/RGD:69282#orthology", "database": "AGR" }, { "id": "HGNC:16270", "url": "https://alliancegenome.org/gene/HGNC:16270#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O95907-1", "protein_name": "Monocarboxylate transporter 3", "gene_name": "SLC16A8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGAGGPRRGEGPPDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRALMRDFDAGYSDTAWVSSIMLAMLYGTGPVSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLTGLGLALNFQPSLIMLGLYFERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFLLLGGLLLHCCACGAVMRPPPGPGPRPRRDSAGDRAGDAPGEAEADGAGLQLREASPRVRPRRRLLDLAVCTDRAFAVYAVTKFLMALGLFVPAILLVNYAKDAGVPDTDAAFLLSIVGFVDIVARPACGALAGLARLRPHVPYLFSLALLANGLTDLSSARARSYGALVAFCVAFGLSYGMVGALQFEVLMAAVGAPRFPSALGLVLLVEAAAVLIGPPSAGRLVDVLKNYEIIFYLAGSEVALAGVFMAVATNCCLRCAKAAPSGPGTEGGASDTEDAEAEGDSEPLPVVAEEPGNLEALEVLSARGEPTEPEIEARPRLAAESV", "length": 504 }, "evidence": [ { "id": "MGI:1929519", "url": "https://alliancegenome.org/gene/MGI:1929519#orthology", "database": "AGR" }, { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121128-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121128-1#orthology", "database": "AGR" }, { "id": "RGD:69282", "url": "https://alliancegenome.org/gene/RGD:69282#orthology", "database": "AGR" }, { "id": "HGNC:16270", "url": "https://alliancegenome.org/gene/HGNC:16270#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P36032-1", "protein_name": "Probable transporter MCH2", "gene_name": "MCH2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSEERHEDHHRDVENKLNLNGKDDINGNTSISIEVPDGGYGWFILLAFILYNFSTWGANSGYAIYLAHYLENNTFAGGSKLDYASIGGLAFSCGLFFAPVITWLYHIFSIQFIIGLGILFQGAALLLAAFSVTLWEIYLTQGVLIGFGLAFIFIPSVTLIPLWFRNKRSLASGIGTAGSGLGGIVFNLGMQSILQKRGVKWALIAQCIICTSLSTIALMLTRTTHQGLRQHKRSYKFELLDYDVLSNFAVWLLFGFVSFAMLGYVVLLYSLSDFTVSLGYTSKQGSYVSCMVSVGSLLGRPIVGHIADKYGSLTVGMILHLVMAILCWAMWIPCKNLATAIAFGLLVGSIMGTIWPTIASIVTRIVGLQKLPGTFGSTWIFMAAFALVAPIIGLELRSTDTNGNDYYRTAIFVGFAYFGVSLCQWLLRGFIIARDEIAVREAYSADQNELHLNVKLSHMSKCLFRYKQLPRRV", "length": 473 }, "evidence": [ { "id": "MGI:1330284", "url": "https://alliancegenome.org/gene/MGI:1330284#orthology", "database": "AGR" }, { "id": "MGI:2443515", "url": "https://alliancegenome.org/gene/MGI:2443515#orthology", "database": "AGR" }, { "id": "MGI:106013", "url": "https://alliancegenome.org/gene/MGI:106013#orthology", "database": "AGR" }, { "id": "MGI:2147716", "url": "https://alliancegenome.org/gene/MGI:2147716#orthology", "database": "AGR" }, { "id": "MGI:1929519", "url": "https://alliancegenome.org/gene/MGI:1929519#orthology", "database": "AGR" }, { "id": "MGI:2385183", "url": "https://alliancegenome.org/gene/MGI:2385183#orthology", "database": "AGR" }, { "id": "HGNC:10928", "url": "https://alliancegenome.org/gene/HGNC:10928#orthology", "database": "AGR" }, { "id": "HGNC:10926", "url": "https://alliancegenome.org/gene/HGNC:10926#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-234", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-234#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120907-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120907-2#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070112-602", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070112-602#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131120-181", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131120-181#orthology", "database": "AGR" }, { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "RGD:3690", "url": "https://alliancegenome.org/gene/RGD:3690#orthology", "database": "AGR" }, { "id": "RGD:620603", "url": "https://alliancegenome.org/gene/RGD:620603#orthology", "database": "AGR" }, { "id": "RGD:3691", "url": "https://alliancegenome.org/gene/RGD:3691#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P53918-1", "protein_name": "Uncharacterized transporter ESBP6", "gene_name": "ESBP6", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSTHSNDYFSASSGMVSETSSEVSSINSSQPVSFSKASIAAPVPCSDLHSTKSNDASRKLSISRTLTNRLNDIKKAVDDDNLQTEENSADVNKILESRFDVADAIRLQHNESVQSKLNIPVTHTTTAGASLSAPSSSAFSASSIQNDTTEHKASMDSKLMRNRLYPASTKHSGKDLEAQGITEFEPDEPTVKKVFTNKSTGQLELPPDGGYGWVVTFCVFLTMFSTWGCNASFGVDLAYYLNHDTYPGASKYDYALIAGLTVFLGQLLSPLVMALMRIIGLRTTMLFGDAVMLAAYLLASFTTKLWQLYVTQGFMVGCSISLIFVPATTVLPGWFLKKRAVAMGVSLLGTGAGGVVYGLATNKMLSDFGNTRWCLRIIGISCSISVLVAIALLKERNPTPAIGLKSPRAMFEQLKAMFSLKVITKPFVVLIALWFMFALFAYNMMVFTLSSYAISKGLSSHDASTLTAILNGSQSIGRPLMGLAGDKFGRANVTIVLTTLLTIYMFAFWIPAHTFVQLIFFSILVGSCVGVANVMNTVLIADMVKPEEFLPAWAFVNYCGAPFLLVCEVIAQALTVEKDKSNPYLHAQIFCGCCFIAALILISILREYSIRMKLTERQAMTNEKLKEWKASEYDTDSADEDWGKLKERKTKYDLLLGPGIKKYFLRMVYPMKV", "length": 673 }, "evidence": [ { "id": "MGI:1330284", "url": "https://alliancegenome.org/gene/MGI:1330284#orthology", "database": "AGR" }, { "id": "MGI:2443515", "url": "https://alliancegenome.org/gene/MGI:2443515#orthology", "database": "AGR" }, { "id": "MGI:106013", "url": "https://alliancegenome.org/gene/MGI:106013#orthology", "database": "AGR" }, { "id": "MGI:2147716", "url": "https://alliancegenome.org/gene/MGI:2147716#orthology", "database": "AGR" }, { "id": "MGI:1929519", "url": "https://alliancegenome.org/gene/MGI:1929519#orthology", "database": "AGR" }, { "id": "MGI:2385183", "url": "https://alliancegenome.org/gene/MGI:2385183#orthology", "database": "AGR" }, { "id": "HGNC:10928", "url": "https://alliancegenome.org/gene/HGNC:10928#orthology", "database": "AGR" }, { "id": "HGNC:10926", "url": "https://alliancegenome.org/gene/HGNC:10926#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-234", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-234#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070112-602", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070112-602#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131120-181", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131120-181#orthology", "database": "AGR" }, { "id": "RGD:3690", "url": "https://alliancegenome.org/gene/RGD:3690#orthology", "database": "AGR" }, { "id": "RGD:620603", "url": "https://alliancegenome.org/gene/RGD:620603#orthology", "database": "AGR" }, { "id": "RGD:3691", "url": "https://alliancegenome.org/gene/RGD:3691#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121108-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121108-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121128-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121128-1#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-051113-248", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-051113-248#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110408-16", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110408-16#orthology", "database": "AGR" }, { "id": "RGD:69282", "url": "https://alliancegenome.org/gene/RGD:69282#orthology", "database": "AGR" }, { "id": "RGD:735117", "url": "https://alliancegenome.org/gene/RGD:735117#orthology", "database": "AGR" }, { "id": "HGNC:16270", "url": "https://alliancegenome.org/gene/HGNC:16270#orthology", "database": "AGR" }, { "id": "HGNC:31037", "url": "https://alliancegenome.org/gene/HGNC:31037#orthology", "database": "AGR" }, { "id": "HGNC:10922", "url": "https://alliancegenome.org/gene/HGNC:10922#orthology", "database": "AGR" }, { "id": "HGNC:26417", "url": "https://alliancegenome.org/gene/HGNC:26417#orthology", "database": "AGR" }, { "id": "HGNC:10924", "url": "https://alliancegenome.org/gene/HGNC:10924#orthology", "database": "AGR" }, { "id": "HGNC:10925", "url": "https://alliancegenome.org/gene/HGNC:10925#orthology", "database": "AGR" }, { "id": "RGD:1359655", "url": "https://alliancegenome.org/gene/RGD:1359655#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P53985-1", "protein_name": "Monocarboxylate transporter 1", "gene_name": "SLC16A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPPAVGGPVGYTPPDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSWISSIMLAVMYGGGPISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIGGLGLAFNLNPALTMIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGLLLNCCVAGALMRPIGPKPTKAGKDKSKASLEKAGKSGVKKDLHDANTDLIGRHPKQEKRSVFQTINQFLDLTLFTHRGFLLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAFLLSILAFVDMVARPSMGLVANTKPIRPRIQYFFAASVVANGVCHMLAPLSTTYVGFCVYAGFFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVVLIISGIYLFIGMGINYRLLAKEQKANEQKKESKEEETSIDVAGKPNEVTKAAESPDQKDTDGGPKEEESPV", "length": 500 }, "evidence": [ { "id": "MGI:106013", "url": "https://alliancegenome.org/gene/MGI:106013#orthology", "database": "AGR" }, { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "RGD:3690", "url": "https://alliancegenome.org/gene/RGD:3690#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110408-16", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110408-16#orthology", "database": "AGR" }, { "id": "HGNC:10922", "url": "https://alliancegenome.org/gene/HGNC:10922#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P53986-1", "protein_name": "Monocarboxylate transporter 1", "gene_name": "Slc16a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPPAIGGPVGYTPPDGGWGWAVLVGAFISIGFSYAFPKSITVFFKEIEVIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYLCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFDIFDWRGSFLILGGLLLNCCVAGSLMRPIGPEQVKLEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTINKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSSYGKSKDFSSEKSAFLLSILAFVDMVARPSMGLAANTKWIRPRIQYFFAASVVANGVCHLLAPLSTTYVGFCVYAGVFGFAFGWLSSVLFETLMDLIGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGIYLFIGMGINYRLLAKEQKAEEKQKREGKEDEASTDVDEKPKETMKAAQSPQQHSSGDPTEEESPV", "length": 493 }, "evidence": [ { "id": "MGI:106013", "url": "https://alliancegenome.org/gene/MGI:106013#orthology", "database": "AGR" }, { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "RGD:3690", "url": "https://alliancegenome.org/gene/RGD:3690#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110408-16", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110408-16#orthology", "database": "AGR" }, { "id": "HGNC:10922", "url": "https://alliancegenome.org/gene/HGNC:10922#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P53987-1", "protein_name": "Monocarboxylate transporter 1", "gene_name": "Slc16a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV", "length": 494 }, "evidence": [ { "id": "MGI:106013", "url": "https://alliancegenome.org/gene/MGI:106013#orthology", "database": "AGR" }, { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "RGD:3690", "url": "https://alliancegenome.org/gene/RGD:3690#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110408-16", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110408-16#orthology", "database": "AGR" }, { "id": "HGNC:10922", "url": "https://alliancegenome.org/gene/HGNC:10922#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P57787-1", "protein_name": "Monocarboxylate transporter 4", "gene_name": "Slc16a3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGGAVVDEGPTGIKAPDGGWGWAVLFGCFIITGFSYAFPKAVSVFFKELMHEFGIGYSDTAWISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQIYLTTGVITGLGLALNFQPSLIMLNRYFNKRRPIANGLAAAGSPVFLCALSPLGQLLQDHYGWRGGFLILGGLLLNCCVCAALMRPLVAPQVGGGTEPRGPQRPPQRLLDLSVFRDRGFLIYAVAASIMVLGLFVPPVFVVSYAKDMGVPDTKAAFLLTILGFIDIFARPTAGFITGLKKVRPYSVYLFSFAMFFNGFTDLTGSTATDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTQKFSSAIGLVLLLEAVAVLIGPPSGGKLLDATKVYKYVFILAGAEVLTSSLVLLLGNFFCIGKRKRPEVTEPEEVASEEKLHKPPVDVGVDSREVEHFLKAEPEKNGEVVHTPETSV", "length": 470 }, "evidence": [ { "id": "RGD:620603", "url": "https://alliancegenome.org/gene/RGD:620603#orthology", "database": "AGR" }, { "id": "HGNC:10924", "url": "https://alliancegenome.org/gene/HGNC:10924#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q08268-1", "protein_name": "Probable transporter MCH4", "gene_name": "MCH4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLNIPIIANSKRFLFSKDHEAQSTRDHDVELETREGPSSGYNPNFNAADAILKKNSDQVDLDVNKLTNVTSRVLNTPEASLIYDDDREFPDGGLKAWLVVFGAFMGLVPVFGLINSLGAIESYISKHQLANISSSTISWIFSLYLAISFLSCILSGGYFDRNGSIGLMCTGTVIYAGGLFALANCKSVWQFILAFSVCSGLGTGILMTPLIGTVATWFLKRRGIATSISTMGGSIGGIVFPIMLRKLYKEVGFQWAIRILSFICLTCLICASVLARERTKPVVQPFKSKAEVAKWYISSVFNWRYFLEGKFLFVAIGASFAESSLTSCATYLASYSMTRGNTENVAYTMITASNAVGILGRYIPGYFADKFIGRFNVEIITISMAALFNFVMWLPFGGNTKVLWAYVCLWGFSTGSILSLTPVCIGQISKTTDFGKRYATVYLLQALVTIPVLPIGGTLIGKGTVANYNHFIIFNSALMAAGAACYIISRHICVGAKLCKF", "length": 501 }, "evidence": [ { "id": "MGI:1330284", "url": "https://alliancegenome.org/gene/MGI:1330284#orthology", "database": "AGR" }, { "id": "MGI:2443515", "url": "https://alliancegenome.org/gene/MGI:2443515#orthology", "database": "AGR" }, { "id": "MGI:106013", "url": "https://alliancegenome.org/gene/MGI:106013#orthology", "database": "AGR" }, { "id": "MGI:2147716", "url": "https://alliancegenome.org/gene/MGI:2147716#orthology", "database": "AGR" }, { "id": "MGI:1929519", "url": "https://alliancegenome.org/gene/MGI:1929519#orthology", "database": "AGR" }, { "id": "HGNC:10928", "url": "https://alliancegenome.org/gene/HGNC:10928#orthology", "database": "AGR" }, { "id": "HGNC:10926", "url": "https://alliancegenome.org/gene/HGNC:10926#orthology", "database": "AGR" }, { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121108-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121108-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121128-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121128-1#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-051113-248", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-051113-248#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110408-16", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110408-16#orthology", "database": "AGR" }, { "id": "RGD:69282", "url": "https://alliancegenome.org/gene/RGD:69282#orthology", "database": "AGR" }, { "id": "RGD:735117", "url": "https://alliancegenome.org/gene/RGD:735117#orthology", "database": "AGR" }, { "id": "RGD:1582896", "url": "https://alliancegenome.org/gene/RGD:1582896#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q08777-1", "protein_name": "Riboflavin transporter MCH5", "gene_name": "MCH5", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSSDSLTPKDTIVPEEQTNQLRQPDLDEDSIHYDPEADDLESLETTASYASTSVSAKVYTKKEVNKGTDIESQPHWGENTSSTHDSDKEEDSNEEIESFPEGGFKAWVVTFGCFLGLIACFGLLNSTGVIESHLQDNQLSSESVSTIGWLFSLFLFVCSASCIISGTYFDRNGFRTIMIVGTVFHVAGLFATANSTKYWHFILSFAIVCGFGNGIVLSPLVSVPAHYFFKRRGTALAMATIGGSVGGVVFPIMLRSFFSMKSDTDPTYGFVWGIRTLGFLDLALLTLSIILVKERLPHVIENSKDGESRWRYILRVYILQCFDAKAFLDMKYLFCVLGTVFSELSINSALTYYGSYATSHGISANDAYTLIMIINVCGIPGRWVPGYLSDKFGRFNVAIATLLTLFIVMFVGWLPFGTNLTNMYVISALYGFCSGSVFSLLPVCCGQISKTEEFGKRYSTMYFVVGFGTLVGIPITGAIISIKTTADYQHYIIFCGLATFVSAVCYIISRAYCVGFKWVRF", "length": 521 }, "evidence": [ { "id": "MGI:1330284", "url": "https://alliancegenome.org/gene/MGI:1330284#orthology", "database": "AGR" }, { "id": "MGI:2443515", "url": "https://alliancegenome.org/gene/MGI:2443515#orthology", "database": "AGR" }, { "id": "MGI:106013", "url": "https://alliancegenome.org/gene/MGI:106013#orthology", "database": "AGR" }, { "id": "MGI:2147716", "url": "https://alliancegenome.org/gene/MGI:2147716#orthology", "database": "AGR" }, { "id": "MGI:1929519", "url": "https://alliancegenome.org/gene/MGI:1929519#orthology", "database": "AGR" }, { "id": "HGNC:10928", "url": "https://alliancegenome.org/gene/HGNC:10928#orthology", "database": "AGR" }, { "id": "HGNC:10926", "url": "https://alliancegenome.org/gene/HGNC:10926#orthology", "database": "AGR" }, { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "RGD:3690", "url": "https://alliancegenome.org/gene/RGD:3690#orthology", "database": "AGR" }, { "id": "RGD:620603", "url": "https://alliancegenome.org/gene/RGD:620603#orthology", "database": "AGR" }, { "id": "RGD:3691", "url": "https://alliancegenome.org/gene/RGD:3691#orthology", "database": "AGR" }, { "id": "RGD:69282", "url": "https://alliancegenome.org/gene/RGD:69282#orthology", "database": "AGR" }, { "id": "RGD:735117", "url": "https://alliancegenome.org/gene/RGD:735117#orthology", "database": "AGR" }, { "id": "RGD:1582896", "url": "https://alliancegenome.org/gene/RGD:1582896#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q0E960-1", "protein_name": "Major facilitator superfamily (MFS) profile domain-containing protein", "gene_name": "Dmel\\CG8389", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDVQSSRVVPDGGYGWIVVAAVALINMTNQSILSVFGQLFVGELQKMQEDTFTAALITNLNSLALNFSGLFIGPAIKSFKPRNVAATGCILVALGLALCAFASESWHFILGYSFFVGFGLGLISPSTFMAINSYFTTKRGRAVGVSLAGAGLGQVLIPHLVRYLLDNHGFRYAVLSMSSLSLFGLFGAAFLKPLNPPAKHNNRKHIRLLTEADGEKTSPLQVVIVPTNQSKIERSPPNVDTLCSRMGQRLVQAMDLELLKDLVFWSIIVGMALVYTATINFTMIFPGFLGQTAQLNSQMVAFCMSLVAGADIVFRLLLPIVTDHLRIPYRVVFLIGIVGLFVARCVLAENQTLPVIITMSVLTGMMKSATVINNNLTISAHCRSEKLAGGLGLSMMSKGVIVITVGQLLGWVRDYADSYLICLYAQGVILLVVVLVWTPEILYRHRRQRCATNKSMETQSIDAAEVAKLNS", "length": 471 }, "evidence": [ { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q3U9N9-1", "protein_name": "Monocarboxylate transporter 10", "gene_name": "Slc16a10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVPSQEEPAAERETNEAQPPGPAPSDDAPLPGPGPSDVSDVAAEKVEVELTRSAGSEPPVPPEGGWGWLVMLAAMWCNGSVFGIQNAYGVLFVSMLDTFKAKDDDNMAFKTAWVGSLSMGMIFFCCPIVSVFTDMFGCRRTAVVGAAVGFIGLMSSSFVSSIEPLYLTYGIIFACGCSFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLGNLISSVKLFNTLRILCIFMFVLFLAGFTYRPLVPSTKEKESGGSRSSFFSRRKLSPPKKVFNFALFKETTYAVWAAGIPLALFGYFVPYVHLMNHVKERFQDVNNKEVLFMCIGITSGVGRLLFGRIADYLPGVKKVYLQVLSFFFIGLMSMMIPLCSAFGALIAVCLAMGLFDGCFISIMAPIAFELVGPQDASQAIGFLLGFMSIPMTVGPPIAGLLHDKLGTYDVAFYLAGIPPFVGGVVLCLIPWIHSKKQRKISKNAGGEKMEKMLENQSSLLSGSSGIFKKDSASII", "length": 512 }, "evidence": [ { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q503M4-1", "protein_name": "Monocarboxylate transporter 12-B", "gene_name": "slc16a12b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAQEKKKGGVLPPDGGWGWMIVAGCFVVTVCTRAVTRCISIFFVEFQMHFAKDYSGTAWIHSLVDCTTMLCAPLGSLIGNQLSCRIAVILGGFLASVGLVLSSFATSLEYLYATLGLLTGLGFALCYTPAIAMVGIYFCERKALAYGIAMSGSGIGTFILAPVVQLLIEHYSWRGALLILGGFVLNLCVCGALLRPIILKEEEACPLPVDSECGYSVKPPTLNGGPTRSAASDAKQRCFQSMQEYHFLLMPDFLVLAGSFLLLASGCSLPFVYLVPYALDVGVGHQHAAFLMSILGVIDIVGNITFGWLTDRRCLKKYRNICYMFAVGMEGLCCLFIPLLRTFVWLVPFSVLYGYFDGAYVALIPVVTSDVVGRQYLSSALGVVYFLHAVPYLVSPPIGGWLVDTTGTYTATFFLSGFALISSSLLLFSVAIIRYCQRNQKKNSLSKIPKLVSCEGKQVDYYPPKNKDLMLIIPATS", "length": 477 }, "evidence": [ { "id": "MGI:2147716", "url": "https://alliancegenome.org/gene/MGI:2147716#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5NC32-1", "protein_name": "Monocarboxylate transporter 11", "gene_name": "Slc16a11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTPKPAGPPDGGWGWVVAAAAFAVNGLSYGLLRSLGLALPDLAEHFERSAQDTAWVSALALAVQQAASPVGSALSTRWGARPVVMVGGVLTSLGLVFSAFARSLLHLYLGLGLLAGSGWALVFAPALGTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQFLLDTFGWRGALLLLGAVTLHLTPCGALLRPLALSGDPLAPPRTPLAALGLGLFKRRAFSVFALGTALIGGGYFVPYVHLGPHALDQGMGGYGAALVVAVAAVGDACARLASGWLADQGWVPLPRLLVVFGSLTGLGVLAMGLVPTVGTEEGWGAPLLAAAGAYGLSAGSYAPLVFGVLPGLVGIGGVVQATGLVMMLMSLGGLLGPPLSGFLRDKTGDFSASFLVCSSFILSGSFIYMGLPRALPSCRPASPPATPPPERGELLPVPQVSLLSAGGTGSIRDTTC", "length": 447 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-120907-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120907-2#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q63344-1", "protein_name": "Monocarboxylate transporter 2", "gene_name": "Slc16a7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPSESSVKATAAPPPFPLPPDGGWGWVVVCASFISIGFSYAFPKAVTVFFNDIKDIFKTTSSQIAWISSIMLAVMYAGGPISSVLVNNYGSRPVVIVGGLLCCTGMILASFSSSVIELYLTVGFIGGLGLAFNLQPALTIIGKYFYRKRPLANGFAMAGSPVFLSTLAPFNQFLFNSYGWKGSFLILGAIFLHSCVAGCLMRPVGPSPRAAKSKSKVGSRQDSSTKRLSKVSTAEKINRFLDFGLFTHRGFLIYLSGNVVLFLGMFAPIIFLAPYAKDKGVDDYNSAFLLSVMAFTDMFARPSVGLIANTSLIRPRIQYLFSVAIMFTGICHLLCPLAHSYTALVVYVIFFGIGFGSISSLLFECLMDQVGASRFSSAVGLVTIVECCPVLFGPPLAGKLLDITGQYKYLYIASGIVVLSSGIYLLICNAINYRLLEKERKREKARRKKSASQASKEMEALSRSKQDDVTVKVSNTHNPPSDRDKESSI", "length": 489 }, "evidence": [ { "id": "MGI:1330284", "url": "https://alliancegenome.org/gene/MGI:1330284#orthology", "database": "AGR" }, { "id": "HGNC:10928", "url": "https://alliancegenome.org/gene/HGNC:10928#orthology", "database": "AGR" }, { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "RGD:3691", "url": "https://alliancegenome.org/gene/RGD:3691#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q66HE2-1", "protein_name": "Monocarboxylate transporter 13", "gene_name": "Slc16a13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVHRTEPPDGGWGWMVVLSAFFQSALVFGVLRSFGVFFVEFVAAFEEQAARVSWIASIGIAVQQFGSPIGSALSTKLGPRPVVMTGGILAALGMLLASFATSLTHLYLSIGLLSGSGWALTFTPTLACLSRYFSQRRSLAMGLALTGVGISSFAFAPLFQWLLNNYAWRGALLLVSALSLHLVACGALLRPLSLTEDTAVGGPWAQITSLLCHGPFLRYTVALTLINTGYFIPYVHLVAHLQDLGWDPLPAAFLLSVAAISDLVGRVASGWLGDAVPGPVARLLMLWTTLTGVSLALFPVAQASTTLVVLAVAYGFTSGALTPVAFSVIPELVGTGRIYCGLGLVQMIESVGGLLGAPLSGYLRDVTGNYTASFVVAGAFLLAGSGVLITLPHFFSCISLSTSRPQDLVIEAPDTKIPLPKEEGLGEN", "length": 428 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-120907-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120907-2#orthology", "database": "AGR" }, { "id": "HGNC:31037", "url": "https://alliancegenome.org/gene/HGNC:31037#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6ZSM3-1", "protein_name": "Monocarboxylate transporter 12", "gene_name": "SLC16A12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPSGSHWTANSSKIITWLLEQPGKEEKRKTMAKVNRARSTSPPDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFTQDYAQTAWIHSIVDCVTMLCAPLGSVVSNHLSCQVGIMLGGLLASTGLILSSFATSLKHLYLTLGVLTGLGFALCYSPAIAMVGKYFSRRKALAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCGALMRPITLKEDHTTPEQNHVCRTQKEDIKRVSPYSSLTKEWAQTCLCCCLQQEYSFLLMSDFVVLAVSVLFMAYGCSPLFVYLVPYALSVGVSHQQAAFLMSILGVIDIIGNITFGWLTDRRCLKNYQYVCYLFAVGMDGLCYLCLPMLQSLPLLVPFSCTFGYFDGAYVTLIPVVTTEIVGTTSLSSALGVVYFLHAVPYLVSPPIAGRLVDTTGSYTAAFLLCGFSMIFSSVLLGFARLIKRMRKTQLQFIAKESDPKLQLWTNGSVAYSVARELDQKHGEPVATAVPGYSLT", "length": 516 }, "evidence": [ { "id": "MGI:2147716", "url": "https://alliancegenome.org/gene/MGI:2147716#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7RTX9-1", "protein_name": "Monocarboxylate transporter 14", "gene_name": "SLC16A14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MYTSHEDIGYDFEDGPKDKKTLKPHPNIDGGWAWMMVLSSFFVHILIMGSQMALGVLNVEWLEEFHQSRGLTAWVSSLSMGITLIVGPFIGLFINTCGCRQTAIIGGLVNSLGWVLSAYAANVHYLFITFGVAAGLGSGMAYLPAVVMVGRYFQKRRALAQGLSTTGTGFGTFLMTVLLKYLCAEYGWRNAMLIQGAVSLNLCVCGALMRPLSPGKNPNDPGEKDVRGLPAHSTESVKSTGQQGRTEEKDGGLGNEETLCDLQAQECPDQAGHRKNMCALRILKTVSWLTMRVRKGFEDWYSGYFGTASLFTNRMFVAFIFWALFAYSSFVIPFIHLPEIVNLYNLSEQNDVFPLTSIIAIVHIFGKVILGVIADLPCISVWNVFLLANFTLVLSIFILPLMHTYAGLAVICALIGFSSGYFSLMPVVTEDLVGIEHLANAYGIIICANGISALLGPPFAGWIYDITQKYDFSFYICGLLYMIGILFLLIQPCIRIIEQSRRKYMDGAHV", "length": 510 }, "evidence": [ { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "HGNC:26417", "url": "https://alliancegenome.org/gene/HGNC:26417#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7RTY0-1", "protein_name": "Monocarboxylate transporter 13", "gene_name": "SLC16A13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARRTEPPDGGWGWVVVLSAFFQSALVFGVLRSFGVFFVEFVAAFEEQAARVSWIASIGIAVQQFGSPVGSALSTKFGPRPVVMTGGILAALGMLLASFATSLTHLYLSIGLLSGSGWALTFAPTLACLSCYFSRRRSLATGLALTGVGLSSFTFAPFFQWLLSHYAWRGSLLLVSALSLHLVACGALLRPPSLAEDPAVGGPRAQLTSLLHHGPFLRYTVALTLINTGYFIPYLHLVAHLQDLDWDPLPAAFLLSVVAISDLVGRVVSGWLGDAVPGPVTRLLMLWTTLTGVSLALFPVAQAPTALVALAVAYGFTSGALAPLAFSVLPELIGTRRIYCGLGLLQMIESIGGLLGPPLSGYLRDVTGNYTASFVVAGAFLLSGSGILLTLPHFFCFSTTTSGPQDLVTEALDTKVPLPKEGLEED", "length": 426 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-120907-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120907-2#orthology", "database": "AGR" }, { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "HGNC:31037", "url": "https://alliancegenome.org/gene/HGNC:31037#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TM99-1", "protein_name": "Monocarboxylate transporter 9", "gene_name": "Slc16a9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEFQKSPDGGWGWVIVVVSFFTQFLSYGSPLAVGVLYVEWLDAFGEGKGKTAWVGSLASGVGLLASPVCSLFVSSFGARPVTIFSGFLVAGGLMLSSLAPNIYFLFFSYGIVVGLGCGLLYTATVTITCQYFDSRRGLALGLISTGSSVGLFIYAALQRMLIEFYGLDGCLLIVGALALNILACGSLMRPLQTSDCPFPEKTAPENVPDRYSMYNEKEKNPEETMNFQDKGYSSEDKCLPNGDWGRETSLPKSLAIAAHTKEPETYKKKVVEQTNFCKQLAKRKWQLYRNYCGETASLFKNKVFSALFIAILLFDIGGFPPSLLMEDVARSYHVREEDLTMPLISIFGIMTAVGKLLLGILADFKWINTLYLYVATLIITGLALCAIPFAKSYVTLAILSGILGFLTGNWSIFPYVTTKTVGIDKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGFCVLLGGFILLLAILPCWDMCNKKLPKPAVPTTFFYKVASNV", "length": 508 }, "evidence": [ { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TMR7-1", "protein_name": "Monocarboxylate transporter 7", "gene_name": "Slc16a6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTQKNSKLCSRANVYTQVPDGGWGWVVAASFFFIEVFTYGVIKSFGVFFNDLMDSFDESNSKISWIISICVFIMTFTAPLSTILTNRFGHRLVVMGGGLLISVGMIAASFSQRVYQMYISIGIVSGLGYCFSFLPTVTILSQYFDKRRSMVTAVASTGECFAMFAFAPAITALKEHIGWRYSLLFVGLLQLNVMVCGALLRPIIIKGPGSPKAIPLEPRREVQYMLENEKTRTSIDSIDSGVELTTSPKNVPSEAKREQEVRVEQQQTLVVGPKHSQKRAPLLDFSILKDRSFICYTLFGLFATLGFFAPSLYIIPLGISLGIHPDRAAFLLSTMAIAEVFGRIGMGLVLNREPIRKIYIELICVILLTVSLFAFTFATEFWGLMLCSVFFGSMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYVFIQSISGLAGPPLAGLLVDQSKIYSRAFYSCAAGMALAAVCLALVRPCKKGLCQNPHSGENQTDGHRGKALQDIPEDFLEMDLGKCEPRAHMKMDPV", "length": 522 }, "evidence": [ { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "RGD:735117", "url": "https://alliancegenome.org/gene/RGD:735117#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BGC3-1", "protein_name": "Monocarboxylate transporter 12", "gene_name": "Slc16a12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTKITRVSLASPPDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFAQDYSQTAWIHSIVDCMTMLCAPLGSVVSNQLSCQAGIMLGGLLASTGFILGSFATSLKHLYLSLGVLTGLGFALCYSPAIAMVGKYFSRRKALAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCGALMRPITLKEDRSVPEKNHNRESQREDCKQASPYSPLTKECTETRLCCSLQQEYGFLLMSDFVVLAVSVLFMAYGCSPLFVYLVPYALSVGVSHHQAAFLMSILGVIDIVGNITFGWLTDRRCLKNYRYVCYLFAVALDGLCYLCLPMLQTFPLLVPFSCTFGYFDGAYVTLIPVVTAEIVGTTSLSSALGVVYFLHAVPYLVSPPIAGWLVDTTGSYTAAFLLCGFAMIFSSILLGFVRIVKRMKRTQVPFPVKDSDPKLQLWTNGSVAYSVARELDQKDEEPLPKARSGCNLT", "length": 486 }, "evidence": [ { "id": "MGI:2147716", "url": "https://alliancegenome.org/gene/MGI:2147716#orthology", "database": "AGR" }, { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CE94-1", "protein_name": "Monocarboxylate transporter 13", "gene_name": "Slc16a13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVRRAEPPDGGWGWMVVLSAFFQSALVFGVLRSFGVFFVEFVAAFEEQAARVSWIASIGIAVQQFGSPIGSALSTKLGPRPVVMTGGILAALGMLLASFATSLTHLYLSIGLLSGSGWALTFTPTMACLSRYFSQRRSLAMGLALTGVGISSFAFAPLFQWLINNYAWRGALLLVSALSLHLMACGALLRPLSLTEDAAVGGPGAQITSLLRHGPFLRYTAALTLINTGFFIPYVHLVAHLQDLGWDPLPAAFLLSVAAVSDLVGRVASGWLGDAVPGPVARLLMLWTTLTGVSLALFPVAQASSTLVVLAVAYGFTSGALTPVAFSVLPELVGTGRIYCGMGLVQMIESIGGLLGAPLSGYLRDVTGNYTASFVVAGAFLLAGSGVLLTLPHFFSCISVSTSRPQDLVIEASDTKIPLPKEEGLGEN", "length": 428 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-120907-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120907-2#orthology", "database": "AGR" }, { "id": "HGNC:31037", "url": "https://alliancegenome.org/gene/HGNC:31037#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8K1C7-1", "protein_name": "Monocarboxylate transporter 14", "gene_name": "Slc16a14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MYTSHEDIGYDLEDDRKAKNKKTLKPHPDIDGGWAWMMVLSSFFVHILIMGSQMALGVLNVEWLEEFHQSRGLTAWVSSLSMGITLIVGPFIGLFINTCGCRQTAIIGGLVNSLGWVLSAYAANVQSLFITFGVAAGLGSGMAYLPAVVMVGRYFQKRRALAQGLSTTGTGFGTFLMTVLLKYLCAEYGWRNAMFIQGALSLNLCVCGALMRPLSPEKLENCPEAEEPCALPAYSTESVKSGGPLGMAEEQDRRPGNEEMVCDLQTQECQGQTHPRKNVCAFRVLKTVSQLTVQVRRGFRDWHSGYFGTASLFTNRMFVAFIFWALFAYSSFVIPFIHLPEIVSLYNLSEQNDTFPLTSIIAILHIFGKVILGAVADLPCISVWNVFLIANFTLVLSIFLLPLMHTYASLAVICALIGFSSGYFSLMPVVTEDLVGTEHLANAYGIIICANGISALLGPPFAGWIFDITQKYDFSFYICGLLYMVGILFLLIQPCIQMIDQSRRKCIEGAHV", "length": 512 }, "evidence": [ { "id": "HGNC:26417", "url": "https://alliancegenome.org/gene/HGNC:26417#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8K1P8-1", "protein_name": "Monocarboxylate transporter 8", "gene_name": "SLC16A2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALPSPASEEAEGPCQEANQEYQEPVCSPVPEPEPEPEPEPEPEPEPVPVPPPEPQPEPEPQPLPDPAPLPVLGFEAEPVQEPEPTPTVETRGTARGFQPPEGGFGWIVVFAATWCNGSIFGIHNSVGILYSMLLEEEKEKNRQVEFQAAWVGALAMGMIFFCSPIVSIFTDRLGCRITATTGAAVAFIGLHTSSFTSSLSLRYFTYGILFGCGCSFAFQPSLVILGHYFQRRLGLANGVVSAGSSIFSMSFPFLIKMLGDRIKLAQTFQVLSTFMFVLTLLSLTYRPLLPSSQDTPSKRGAHTLRQRFLVQFRKYFNMRVFRQRTYRIWAFGIAAAALGYFVPYVHLMKYVEDKFKEIKETWVLLVCIGATSGLGRLVSGHISDSIPGLKKIYLQVLSFLLLGLMSMMIPLCRDFGGLIVVCLFLGLCDGFFITIMAPIAFELVGPMQASQAIGYLLGMMALPMIAGPPIAGLLRNCFGNYHVAFYFAGVPPIIGAVILFFVPLMHQRMFKKEQRESSKDKMLSHDPDPNGELLPGSPTPEEPI", "length": 545 }, "evidence": [ { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8NCK7-1", "protein_name": "Monocarboxylate transporter 11", "gene_name": "SLC16A11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTPQPAGPPDGGWGWVVAAAAFAINGLSYGLLRSLGLAFPDLAEHFDRSAQDTAWISALALAVQQAASPVGSALSTRWGARPVVMVGGVLASLGFVFSAFASDLLHLYLGLGLLAGFGWALVFAPALGTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQLLLDTFGWRGALLLLGAITLHLTPCGALLLPLVLPGDPPAPPRSPLAALGLSLFTRRAFSIFALGTALVGGGYFVPYVHLAPHALDRGLGGYGAALVVAVAAMGDAGARLVCGWLADQGWVPLPRLLAVFGALTGLGLWVVGLVPVVGGEESWGGPLLAAAVAYGLSAGSYAPLVFGVLPGLVGVGGVVQATGLVMMLMSLGGLLGPPLSGFLRDETGDFTASFLLSGSLILSGSFIYIGLPRALPSCGPASPPATPPPETGELLPAPQAVLLSPGGPGSTLDTTC", "length": 447 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-120907-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120907-2#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R0M8-1", "protein_name": "Probable monocarboxylate transporter 5", "gene_name": "Slc16a4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVKKEKTPSPYTKPLDGGWGWMVVLHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIGWIGSIMSSLRFSAGPLAAIICDVLGEKATSILGTFLVSGGYVISSWATGIPFLCVTMGLLPGLGSAFLYQVAAVVITKYFKKRLGLSTAIARSGMGLTFLLAPFTKFLIDLYDWTGALILFGAIILNLVPSSMLLRPIHSQSNNNSDIENKGSILSATEPEASYKTETSKCKETQEPFIKDSTMKKSEQPTTTLTVLGNQSEEFSNRPHRNRPLLMSNGKSHKKKFVSWNCKQKLLDISLFRNPFFYIFTWSFLLSQLAYFIPTFHLVARAKTLGIDVMDASYLVSVAGITETVSQLISGWIADQNWIKKYQYHKSYLILCGVTNLLAPLATTFPLLMAYTILFAIFAGGYLALILPVLVDLSKNSRVHKFLGYASFFAGIAVLSGPPIAGWIYDYTQTYTGSFYFSGTCYILSSVSLFFVPLAERWKRKQSDLLRTTIK", "length": 500 }, "evidence": [ { "id": "MGI:2385183", "url": "https://alliancegenome.org/gene/MGI:2385183#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070112-602", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070112-602#orthology", "database": "AGR" }, { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "HGNC:10925", "url": "https://alliancegenome.org/gene/HGNC:10925#orthology", "database": "AGR" }, { "id": "RGD:1359655", "url": "https://alliancegenome.org/gene/RGD:1359655#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TF71-1", "protein_name": "Monocarboxylate transporter 10", "gene_name": "SLC16A10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVLSQEEPDSARGTSEAQPLGPAPTGAAPPPGPGPSDSPEAAVEKVEVELAGPATAEPHEPPEPPEGGWGWLVMLAAMWCNGSVFGIQNACGVLFVSMLETFGSKDDDKMVFKTAWVGSLSMGMIFFCCPIVSVFTDLFGCRKTAVVGAAVGFVGLMSSSFVSSIEPLYLTYGIIFACGCSFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLRVLIDSVGLFYTLRVLCIFMFVLFLAGFTYRPLATSTKDKESGGSGSSLFSRKKFSPPKKIFNFAIFKVTAYAVWAVGIPLALFGYFVPYVHLMKHVNERFQDEKNKEVVLMCIGVTSGVGRLLFGRIADYVPGVKKVYLQVLSFFFIGLMSMMIPLCSIFGALIAVCLIMGLFDGCFISIMAPIAFELVGAQDVSQAIGFLLGFMSIPMTVGPPIAGLLRDKLGSYDVAFYLAGVPPLIGGAVLCFIPWIHSKKQREISKTTGKEKMEKMLENQNSLLSSSSGMFKKESDSII", "length": 515 }, "evidence": [ { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q91Y77-1", "protein_name": "Monocarboxylate transporter 10", "gene_name": "Slc16a10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVPSQEEPAAAERETNEAQPPGPAPSDDAPLPVPGPSDVSDGSVEKVEVELTRSTGNQEPPEPPEGGWGWLVMLAAMWCNGSVFGIQNAYGVLFVSMLETFGAKDDDNMAFKAAWVGSLSMGMIFFCCPIVSVFTDMFGCRRTAVLGAAVGFVGLMSSSFVSSIEPLYFTYGVVFACGCSFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLGNLTSTVGLCYTLRILCIFMFVLFLAGFTYRPLVPSSKEKESEDSRSSFFSRRKLSPPKKIFNFALFKETAYAVWAAGIPLALFGYFVPYVHLMNHVKERFKDVNNKEVLFMCIGVTSGVGRLLFGRIADYLPGVKKVYLQVLSFFFIGLTSMMIPLCSVFGALIALCLIMGLFDGCFISIMAPIAFELVGPQDASQAIGFLLGFMSIPMTVGPPVAGLLHDKLGSYDLAFYLAGIPPFIGGAVLCLIPWIHSKKQREISKNTGGEKMEKMLANQSSLLSSSSGIFKKESDSII", "length": 514 }, "evidence": [ { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9V3F9-1", "protein_name": "Outsiders, isoform A", "gene_name": "out", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEKSSLTEKNHTQVYNDTTKPKKPKRRDKSDLGPDFVAPDGGWGWVVCLAAGLNNFFLFPALQQYGLIYRVRMQSLGFDAKQTTTIVNVVMAISSLVGIVNGAMFRRFTFRQVALTGTSLAFLGVFLSAFCTTFWQYIICLSAIFGIGLGLAMAATSLAVNTYFKLKRRRATGFSWTITGLGPIFFPQVSTVLLGYYGAQGTILIYAGIAMNAILCALTLQPVLWHVKKPEKPVHNTIEGIAETEKLQPELLEANGNLLSPSNDPWKDYECKYCQYQKRSKRGLFSSQYLFNVDDPERPGYEITEPGTPMLARANDGWFGSKLSLTSESAGGARSRTRQALMRQVSSRSRENLDRLEQNRHDQGPDTPSAAALYKPNYFNREREDLDRYASKTSVYSRPGQDELLRCTCAEDKALLQKTAESLQVNLFNNSADNTEAEEEAKRRMTFFQKVSKFFDLDLLRDFTFVNLAVGMSIMMFGEMNFSVLTPFILNSFGYTDTQISLVMSLLACMDISVRFLAPLALEKVKLDNRVLFAFGILCIAVGRVVVAFTDSYEIMIGVFLLIGFGKAFRTIFSPLIIPSYVPLNRLPAASGLQLIFNTIFSFAMGPILGILTEAYGYAATIHTINALTLLALLLWLAESVVRRILGIPSKGLGQ", "length": 655 }, "evidence": [ { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VQU7-1", "protein_name": "Major facilitator superfamily (MFS) profile domain-containing protein", "gene_name": "GH25970", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVIQCTCDCNCSDSRDNRSVISCLLPGRSQPYKLGSSFGGDDMEQRIPYYRRLSNTSSALYGSCPQLLPSSSSTNNRHSWLRIPKNPQENPSENPSENPRQYSSLVRPKQRSPVLCNKCALXRRYNLSCEHPKQTAGHPGSGNTDQTAQTKPDKDSTNQRYLCYECRFNNQPLAWWVSCPRLSYLPAEQTKMQSTTTPTRHCHGGVGTQTTLPQTTSTPPTLPRFPSKRHCDNFGSYATLPTIEHQMTMPMMPHCSRHGGGGGGGVVGVGGLGGAVGSGMPSVMPAPPPPRYANPNINGCCYMYNPMPPAHQSHHQHDHHHAQQHHPVAQHQHHPHQYGPQYCLCDNWYHQPPPTQQQQHHHQQRAKNLMANGGCYFGYEANHHPSLHATTPHPSHITDEEDSAFPGLADREFHLLHRNIPALRRTGVDTTRIRQYFYPDGGWGWIICGVSFLVHILTTGLQLSYGLLWFYAVQYLHNTSGIELLGALSWSVSMVATSFVVSLCRKRSIRLLSIVGGLVMPLGILFTSFATEFGQVVFSYGIVFGVGVAMVREASTVMLGNYFKRRRQFVEMVAMSGEGVGIALFSVILKEGVGKAGWRLGLQIVAALTALSFFMGLMYRPASLYHPQRRAIQHLKNQRKKMREKKPILSQDVESTPKYFFLDISSLKSVTVKILLMTSSVASFGIYTPMFLMALNAAEQGSDVQELVLLQTFLGISMALGVVIAGALLRRCFVIRHFVINTKIVTQLFLSIVALAILFLSFVMGYTGLCILSWLYGIGLGGFQYSLKILALERIKLKHFSKAWGFIRGVESVPVLISVPLTSFLNDYSLKYGRAGYYICSAAAAISGIIIFFISEPQQQHQQQQQQLHHHYQQRNGHLATPTLMRHASARQHRPHLPMDYGYGEYPAPDLLSRSCISLNQMEPYLQANFCQRHMLQQQQQQQQQQQHSHLQQLACHNLDLQPHQGREAYQLGQGSIGAKMGKRLQRSLSFIQQHSNCCDGQMYCSWHSTYELGCHKSNKNPGSADRQPLICTCSSPNRNPVTYGTHGPTGPPGPTGPPGPPSSTRSRSVPEGLSTMSQQCNCRQGPATFAAPTREFIYVPHAYASLQRTPHRHSQGAGSGPGPGNSALRNNPQCRLKRSQSLCRPNAVQFVEQITTSV", "length": 1159 }, "evidence": [ { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VWJ0-1", "protein_name": "Major facilitator superfamily (MFS) profile domain-containing protein", "gene_name": "Yqy", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTDNGNNHNNNNNNNNDEALRLRLPEEQAEQLLPKNGSAGQTKIAPPTHTHSIAAASVPQKVPAKKKRDKSDLGEDFVAPDGGWGWLVSVASGVNILVTFALAQQFGILFRDRMAGLGISSSELTTIINTQIAVSAFTGLLNGPLFRRYTYRVVALVGSVLTFLGLFWMVFADTFAVYIMSFSILYGFGRGLTVSASSLAVNTYFKVKRRTATAFQFGVAGLGPIVCPYFATYMLYEFGVQGTTLLFAGASLHTIACSLIYQPVKWHVVKRDRDAEALQQVQPLAEREDQDEDIIKNVVEPETPVLPRANDGWFGSRASLNSVGTRNRLNTWEKSDSNGHVELKRLSSKDSNPGRQLRSISVSHSIKEEEATGYNSDHEVQHTELTEKEKQELEDEKERQRRKKLPFYMKVVIFFDMDLLRDITYVNLAVGITLINFVEINFAILTPFILSDLGFNKDQIALAMSTLGFFDLVVRFLIPLITAKINLSNRTFFVVGILGMCIGRMFLSMTSNFYVMMAIFLWLGLNKAFRTVFWSLIIPSYVPLKRLPAAAGLQLLMSGTFSMIFGPLIGLIRDHTSYAVTLNLLNALCVMAFAGWYLEDFIRARSRKSPPVKSIN", "length": 616 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-131120-181", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131120-181#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VWJ1-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG8034", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MASKQPRKVAPDGGWGWVACFGVSLVNLATRSIEPSFGLLFGDTLKELNVGTTGAAVIISALDVCMNFSGLFVGPLLKEFSYRKVAIAGSLLCGLGLALTSPATSMAHILSTYSVINGIGVGLSTSAAFVALNHYFKHKRGQAVGLSMAGTAMGMLIMPQLVRILLEAYDFRGAVLLLAGVALNATVGSVLLQPVKWHMKEEFDDEELMCISALPTPQPQLTVGGAGGAASAGAPVFKVIKEDGNEEDALPEMNTLLFHKPHPHQHSMRKNYSEMAMNTMNGSRLGIPKRPTFPRIMSLAGVQSAAHGAGGDSGGYTSQAEVNATQLRCRKASVTSNLSYMDFTGSILQVHLNTGDDEFEQNDRELRRVGTATGSIVLGGHRDSFIKMKPTELDKQAEAAAALDEEAKKKAKKPGFWRRFADLLDIDMLKDKMFLNLLFGLSIFYVAEMNFKMVTPFFFANLGYQKTDVAFCLSITAITDIAARIVLPPIFDRTTIKKRTIFLVSIIFVALTRSIMAEQTEWTQLMIWLSICGFFRGSALSNFTLTVSEYCSLEKLPSAFGWHLVGKALFVITFGPLIGLIRDVTDSYPICIHTQSVCIMICATAWGIEYLVEYIQSRRRTADAAQLPTQDVGATTTATSDQNDVKL", "length": 647 }, "evidence": [ { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VWK0-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG14196", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEKKVYQDTTRPLPRVSRARYYNKHDKSDLGDDFVAPDAGWAWIVCVAAGVSNLSIYPCLQQFGFLFRERLSDLGMSSSQITAIINANPAVSACTGLLNGPMFRRFTFRQVAMAGSLLISGSLILTAFCETFLSYMVAYALLFGFGMGISVSASSLAINTYFQKKRRRAAGFSWTITGLGPIFLPHLVTFLLTIYGVQGTTLLFAAISLHSFVCALIYQPVRYHVKPPVEQLADQEQQAEALCAHCSWQQKREPGGIFSSQYLCQDDDAQRPGYEICEPGTPMLSRANDGWYGSRLSLTSGRLRFRTISSSKDLEQTQRLHCPISEEQNHESDEFLRPNNFRRERVESNLEAKLCCQCSAKREEHNNNRKEKEAEAEEAGMESAPLHDPQMSFLAKVVTFFDLDLLRDFTFVNLVAGLTIINFGELNFSILTPFILVDFGFDTPQITLAMSLLAGLDITMRFMVPFLTEKIPWDNRVFFLIGVVGIALGRTVVACTRSYSLILCSFVWIGLCKGVRTIFWPLIIPGYVPLNRLPGASGLQLLISGLFTLIGGPFVGLVRDRYDYSVTLHCLNMMSFVAATSWSLEALIRRHRRKQRLVNS", "length": 600 }, "evidence": [ { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W509-1", "protein_name": "Monocarboxylate transporter 1, isoform B", "gene_name": "Mct1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVHGPPARRKSQQQHEACEMDMERQPTPPDGGWGWVVVFGSFMIHIVTDGMTYSFGIFYNEFLDYFNEGKGYTAWIASIMVGVTFSSGPISSSFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGFGTGLGFGLIYLPAIVSVTQYFEAKRSLATGIAVCGSGFGTFVFAPLTEFLIGNYGWRGAMLIIGGIVLNCIIFGAMFRPLELEAPPQTPPNTPSTPKLAKKSAIIDQNTTAAELEPLKVLPKDQYLQLPQRTDTAVSGGALCRSNSVGHNLKPNLNNNSNGAVNGQGPTLVTPPQAVVKSTSNDDIARKCHSQLQLTPLRDAHRERSASGTMYRPDALYQGSLHNLPDYVSSRNDLSRSMSGSGVIKRYGSLRQSNNVSQSQEEAKCCGCITCSKETRDTFAEMMNFSLLKDMVFVIFSVSNFCTSIGFNVPYLYVVAYAETLKLTKTDASYLISTIGVANTVGRIILGYISDKPWVNRLLVYNVCLTACGVSTAMVPLCHDFQSLAFYCCVFGFTIGAYVGLTSVILVDLLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMYDLTDSYAPAFLMAGLMIAISGLVMFAIPPLQRLQVRKSERKPHTEHLALS", "length": 626 }, "evidence": [ { "id": "MGI:1330284", "url": "https://alliancegenome.org/gene/MGI:1330284#orthology", "database": "AGR" }, { "id": "MGI:2443515", "url": "https://alliancegenome.org/gene/MGI:2443515#orthology", "database": "AGR" }, { "id": "MGI:2147716", "url": "https://alliancegenome.org/gene/MGI:2147716#orthology", "database": "AGR" }, { "id": "MGI:1929519", "url": "https://alliancegenome.org/gene/MGI:1929519#orthology", "database": "AGR" }, { "id": "MGI:2385183", "url": "https://alliancegenome.org/gene/MGI:2385183#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070112-602", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070112-602#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131120-181", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131120-181#orthology", "database": "AGR" }, { "id": "RGD:620603", "url": "https://alliancegenome.org/gene/RGD:620603#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121108-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121108-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121128-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121128-1#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-051113-248", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-051113-248#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110408-16", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110408-16#orthology", "database": "AGR" }, { "id": "HGNC:31037", "url": "https://alliancegenome.org/gene/HGNC:31037#orthology", "database": "AGR" }, { "id": "HGNC:26417", "url": "https://alliancegenome.org/gene/HGNC:26417#orthology", "database": "AGR" }, { "id": "HGNC:10924", "url": "https://alliancegenome.org/gene/HGNC:10924#orthology", "database": "AGR" }, { "id": "HGNC:10925", "url": "https://alliancegenome.org/gene/HGNC:10925#orthology", "database": "AGR" }, { "id": "RGD:1359655", "url": "https://alliancegenome.org/gene/RGD:1359655#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9W0L6", "url": "https://www.uniprot.org/uniprotkb/Q9W0L6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "monocarboxylic acid transmembrane transporter activity", "id": "GO:0008028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008028", "evidence": [ { "database": "UniProtKB", "id": "Q9W0L6", "url": "https://www.uniprot.org/uniprotkb/Q9W0L6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "monocarboxylic acid transport", "id": "GO:0015718", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015718", "evidence": [ { "database": "UniProtKB", "id": "Q9W0L6", "url": "https://www.uniprot.org/uniprotkb/Q9W0L6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 166, "end_pos": 168, "annotation": "n_glycosylation_sequon" }, { "start_pos": 398, "end_pos": 400, "annotation": "n_glycosylation_sequon" }, { "start_pos": 415, "end_pos": 417, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 166, "end_pos": 168 }, { "start_pos": 398, "end_pos": 400 }, { "start_pos": 415, "end_pos": 417 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9W0M4-1", "uniprot_ac": "Q9W0M4", "uniprot_id": "Q9W0M4_DROME", "mass": { "chemical_mass": 26154.0, "monoisotopic_mass": 26154.0 }, "refseq": { "ac": "NP_001286891", "name": "uncharacterized protein, isoform E", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001286891" }, "gene_names": [ { "name": "Dmel\\CG13887", "type": "recommended", "evidence": [ { "id": "Q9W0M4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W0M4" } ] }, { "name": "CG13887", "type": "synonym", "evidence": [ { "id": "NP_001286891", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001286891" }, { "id": "Q9W0M4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W0M4" } ] }, { "name": "Dmel\\CG13887", "type": "synonym", "evidence": [ { "id": "NP_001286891", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001286891" } ] }, { "name": "Dmel_CG13887", "type": "synonym", "evidence": [ { "id": "Q9W0M4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W0M4" } ] } ], "protein_names": [ { "name": "Endoplasmic reticulum transmembrane protein", "type": "recommended", "evidence": [ { "id": "Q9W0M4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W0M4/entry#names_and_taxonomy" } ] }, { "name": "CG13887-PE", "type": "synonym", "evidence": [ { "id": "NP_001286891", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001286891" } ] }, { "name": "uncharacterized protein, isoform E", "type": "synonym", "evidence": [ { "id": "NP_001286891", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001286891" } ] } ], "function": [ { "annotation": "May play a role in anterograde 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Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W0M4", "url": "https://www.uniprot.org/uniprotkb/Q9W0M4" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W0M4", "url": "https://www.uniprot.org/uniprotkb/Q9W0M4" } ], "reference": [ { "type": "PubMed", 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F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W0M4", "url": "https://www.uniprot.org/uniprotkb/Q9W0M4" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W0M4", "url": "https://www.uniprot.org/uniprotkb/Q9W0M4" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"gene_name": "Bcap29", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTIQWAAVASFLYAEIGLILLFCLPFIPPQRWQKIFSFSVWGKIASFWNKAFLTIIILLIILFLDAVREVRKYSSTNVVEKNSAIRPSAFEHTQMKLFRSQRNLYISGFSLFFWLVLRRLVTLITQLAKEIANKGVLKIQAENTNKAAKKFMEENEKLKLGLRNDNAEEHLLEAENKKLIESKENLKTELKKASDALLKAQNDVMTMKIQSERLSKEYDRLLKEHSELQNRLEKEKKKGL", "length": 240 }, "evidence": [ { "id": "MGI:101917", "url": "https://alliancegenome.org/gene/MGI:101917#orthology", "database": "AGR" }, { "id": "HGNC:24131", "url": "https://alliancegenome.org/gene/HGNC:24131#orthology", "database": "AGR" }, { "id": "RGD:1359431", "url": "https://alliancegenome.org/gene/RGD:1359431#orthology", "database": "AGR" }, { "id": "FB:FBgn0035165", "url": "https://alliancegenome.org/gene/FB:FBgn0035165#orthology", "database": "AGR" }, { "id": "SGD:S000004643", "url": "https://alliancegenome.org/gene/SGD:S000004643#orthology", "database": "AGR" }, { "id": "SGD:S000001548", "url": 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"Vti1a-PA", "type": "synonym", "evidence": [ { "id": "NP_612053", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_612053" } ] }, { "name": "vesicle transport through interaction with t-SNAREs 1a", "type": "synonym", "evidence": [ { "id": "NP_612053", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_612053" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W0N6", "url": "https://www.uniprot.org/uniprotkb/Q9W0N6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Vti1a", "url": "https://www.uniprot.org/uniprotkb/Q9W0N6", "locus": { "chromosome": "3L", "start_pos": 691486, "end_pos": 692919, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0260862", "url": "https://www.ensemblgenomes.org/id/FBgn0260862" } ] } } ], "crossref": [ { "id": "FB:FBgn0260862", "url": "https://alliancegenome.org/gene/FB:FBgn0260862", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0260862", "url": "https://bgee.org/?page=gene&gene_id=FBgn0260862", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd15891", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15891", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0260862", "url": "https://flybase.org/reports/FBgn0260862", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "38085", "url": "https://www.ncbi.nlm.nih.gov/gene/38085", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000727", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000727", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007705", "url": 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"id": "PTHR21230", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21230", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21230:SF26", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21230:SF26", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05008", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05008", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q9W0N6", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q9W0N6", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-DME-6811438", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6811438", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-6811440", "url": 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"Q9W0N6-1", "url": "https://www.uniprot.org/uniprotkb/Q9W0N6/entry#Q9W0N6-1", "sequence": { "sequence": "MSLLEQYEQQYATLIAEITAHIGRLQQQNNNSERHDLCSKIDSSLPEAQELLEQMGLEVRELNPGLRSSFNGKLQVAQAELKRLQAEYRLTKDKQRSQANTFTTLDLGDSYEDVSISTDQRQRLLDNSERIERTGNRLTEGYRVALETEQLGAQVLNDLHHQRETLQGARARLRETNAELGRASRTLNTMMLRALREKVVLYGVGVCFVVAVGVSLYLTFAPSSSSTASS", "length": 230, "header": "tr|Q9W0N6-1|Q9W0N6_DROME Isoform 1 of Vesicle transport through interaction with t-SNAREs 1a OS=Drosophila melanogaster OX=7227 GN=Vti1a PE=3 SV=1 CANONICAL=Q9W0N6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W0N6", "url": "https://www.uniprot.org/uniprotkb/Q9W0N6" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W0N6", "url": "https://www.uniprot.org/uniprotkb/Q9W0N6" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W0N6", "url": "https://www.uniprot.org/uniprotkb/Q9W0N6" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W0N6", "url": "https://www.uniprot.org/uniprotkb/Q9W0N6" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W0N6", "url": "https://www.uniprot.org/uniprotkb/Q9W0N6" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W0N6", "url": "https://www.uniprot.org/uniprotkb/Q9W0N6" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W0N6", "url": "https://www.uniprot.org/uniprotkb/Q9W0N6" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W0N6", "url": "https://www.uniprot.org/uniprotkb/Q9W0N6" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W0N6", "url": "https://www.uniprot.org/uniprotkb/Q9W0N6" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W0N6", "url": "https://www.uniprot.org/uniprotkb/Q9W0N6" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W0N6", "url": "https://www.uniprot.org/uniprotkb/Q9W0N6" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], 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"database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AAA9S2Q2-1", "protein_name": "Vesicle transport through interaction with t-SNAREs 1A", "gene_name": "VTI1A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSSDFEGYEQDFAVLTAEITNKIARVPRLPPDEKKQMVANVEKQLEEAKELLEQMDLEVREIPPQSRGMYSNRMRSYKQEMGKLETDFKRSRIAYSDEVRNELLGDDGNSSENQRAHLLDNTERLERSSRRLEAGYQIAVETEQIGQEMLENLSHDREKIQRARERLRETDANLGKSSRVLTGMLRRGAVNCVGRKTRGSTLPPGQEAAPTRGTEPLATPLPEQQVILRVGCMDRLSPSPHLIWSPRHSAVFRGSRAASQDSPRLDARHNEFVPAEPPALIFQILQYTKRETFVQISRILIAQVNRHCLLIFPLQ", "length": 315 }, "evidence": [ { "id": "Q9W0N6", "url": "https://omabrowser.org/oma/group/Q9W0N6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O88384-1", "protein_name": "Vesicle transport through interaction with t-SNAREs homolog 1B", "gene_name": "Vti1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAASAASSEHFEKLHEIFRGLLEDLQGVPERLLGTAGTEEKKKLVRDFDENQQEANETLAEMEEELRYAPLTFRNPMMSKLRNYRKDLAKLHREVRSTPLTAAPGGRGDLKYGTYTLENEHLNRLQSQRALLLQGTESLNRATQSIERSHRIATETDQIGTEIIEELGEQRDQLERTKSRLVNTNENLSKSRKILRSMSRKVITNKLLLSVIILLELAILVGLVYYKFFRHH", "length": 232 }, "evidence": [ { "id": "SGD:S000004810", "url": "https://alliancegenome.org/gene/SGD:S000004810#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O89116-1", "protein_name": "Vesicle transport through interaction with t-SNAREs homolog 1A", "gene_name": "Vti1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSDFEGYEQDFAVLTAEITSKIARVPRLPPDEKKQMVANVEKQLEEARELLEQMDLEVREIPPQSRGMYSNRMRSYKQEMGKLETDFKRSRIAYSDEVRNELLGDAGNSSENQRAHLLDNTERLERSSRRLEAGYQIAVETEQIGQEMLENLSHDREKIQRARDRLRDADANLGKSSRILTGMLRRIIQNRILLVILGIIVVIAILTAIAFFVKGH", "length": 217 }, "evidence": [ { "id": "MGI:1855699", "url": "https://alliancegenome.org/gene/MGI:1855699#orthology", "database": "AGR" }, { "id": "HGNC:17792", "url": "https://alliancegenome.org/gene/HGNC:17792#orthology", "database": "AGR" }, { "id": "FB:FBgn0260862", "url": "https://alliancegenome.org/gene/FB:FBgn0260862#orthology", "database": "AGR" }, { "id": "RGD:621490", "url": "https://alliancegenome.org/gene/RGD:621490#orthology", "database": "AGR" }, { "id": "SGD:S000004810", "url": "https://alliancegenome.org/gene/SGD:S000004810#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P58200-1", "protein_name": "Vesicle transport through interaction with t-SNAREs homolog 1B", "gene_name": "Vti1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATSAASSEHFEKLHEIFRGLLEDLQGVPERLLGTAGTEEKKKLVRDFDEKQQEANETLAEMEEELRYAPLTFRNSMMSKLRNYRKDLAKLHREVRSTPLTATPGGRGDLKFGTYTLENEHLNRLQSQRALLLQGTESLNRATQSIERSHRIAAETDQIGSEIIEELGEQRDQLERTKSRLVNTNENLSKSRKILRSMSRKVITNKLLLSVIIVLELAILVGLVYYKFFRHH", "length": 232 }, "evidence": [ { "id": "SGD:S000004810", "url": "https://alliancegenome.org/gene/SGD:S000004810#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q04338-1", "protein_name": "t-SNARE VTI1", "gene_name": "VTI1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSSLLISYESDFKTTLEQAKASLAEAPSQPLSQRNTTLKHVEQQQDELFDLLDQMDVEVNNSIGDASERATYKAKLREWKKTIQSDIKRPLQSLVDSGDRDRLFGDLNASNIDDDQRQQLLSNHAILQKSGDRLKDASRIANETEGIGSQIMMDLRSQRETLENARQTLFQADSYVDKSIKTLKTMTRRLVANKFISYAIIAVLILLILLVLFSKFK", "length": 217 }, "evidence": [ { "id": "MGI:1855699", "url": "https://alliancegenome.org/gene/MGI:1855699#orthology", "database": "AGR" }, { "id": "HGNC:17792", "url": "https://alliancegenome.org/gene/HGNC:17792#orthology", "database": "AGR" }, { "id": "FB:FBgn0260862", "url": "https://alliancegenome.org/gene/FB:FBgn0260862#orthology", "database": "AGR" }, { "id": "RGD:621490", "url": "https://alliancegenome.org/gene/RGD:621490#orthology", "database": "AGR" }, { "id": "SGD:S000004810", "url": "https://alliancegenome.org/gene/SGD:S000004810#orthology", "database": "AGR" }, { "id": "Q9W0N6", "url": "https://omabrowser.org/oma/group/Q9W0N6/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q96AJ9-2", "protein_name": "Vesicle transport through interaction with t-SNAREs homolog 1A", "gene_name": "VTI1A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSDFEGYEQDFAVLTAEITSKIARVPRLPPDEKKQMVANVEKQLEEAKELLEQMDLEVREIPPQSRGMYSNRMRSYKQEMGKLETDFKRSRIAYSDEVRNELLGDDGNSSENQRAHLLDNTERLERSSRRLEAGYQIAVETEQIGQEMLENLSHDREKIQRARERLRETDANLGKSSRILTGMLRRIIQNRILLVILGIIVVITILMAITFSVRRH", "length": 217 }, "evidence": [ { "id": "MGI:1855699", "url": "https://alliancegenome.org/gene/MGI:1855699#orthology", "database": "AGR" }, { "id": "HGNC:17792", "url": "https://alliancegenome.org/gene/HGNC:17792#orthology", "database": "AGR" }, { "id": "FB:FBgn0260862", "url": "https://alliancegenome.org/gene/FB:FBgn0260862#orthology", "database": "AGR" }, { "id": "RGD:621490", "url": "https://alliancegenome.org/gene/RGD:621490#orthology", "database": "AGR" }, { "id": "SGD:S000004810", "url": "https://alliancegenome.org/gene/SGD:S000004810#orthology", "database": "AGR" }, { "id": "Q9W0N6", "url": "https://omabrowser.org/oma/group/Q9W0N6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JI51-1", "protein_name": "Vesicle transport through interaction with t-SNAREs homolog 1A", "gene_name": "Vti1a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSADFEGYEQDFAVLTAEITSKISRVPRLPPDEKKQMVANVEKQLEEARELLEQMDLEVREIPPQSRGMYSNRMRSYKQEMGKLETDFKRSRIAYSDEVRNELLGDAGNSSENQLIKLREERAHLLDNTERLERSSRRLEAGYQIAVETEQIGQEMLENLSHDRERIQRARERLRETDANLGKSSRILTGMLRRIIQNRILLVILGIIVVITILTAITFFVRGH", "length": 224 }, "evidence": [ { "id": "MGI:1855699", "url": "https://alliancegenome.org/gene/MGI:1855699#orthology", "database": "AGR" }, { "id": "HGNC:17792", "url": "https://alliancegenome.org/gene/HGNC:17792#orthology", "database": "AGR" }, { "id": "FB:FBgn0260862", "url": "https://alliancegenome.org/gene/FB:FBgn0260862#orthology", "database": "AGR" }, { "id": "RGD:621490", "url": "https://alliancegenome.org/gene/RGD:621490#orthology", "database": "AGR" }, { "id": "SGD:S000004810", "url": "https://alliancegenome.org/gene/SGD:S000004810#orthology", "database": "AGR" }, { "id": "Q9W0N6", "url": "https://omabrowser.org/oma/group/Q9W0N6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9SEL6-1", "protein_name": "Vesicle transport v-SNARE 11", "gene_name": "VTI11", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSDVFDGYERQYCELSASLSKKCSSAISLDGEQKKQKLSEIKSGLENAEVLIRKMDLEARTLPPNLKSSLLVKLREFKSDLNNFKTEVKRITSGQLNAAARDELLEAGMADTKTASADQRARLMMSTERLGRTTDRVKDSRRTMMETEEIGVSILQDLHGQRQSLLRAHETLHGVDDNIGKSKKILTDMTRRMNKNKWTIGAIIIALIAAIFIILYFKLTK", "length": 221 }, "evidence": [ { "id": "Q9W0N6", "url": "https://omabrowser.org/oma/group/Q9W0N6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q9W0N6", "url": "https://www.uniprot.org/uniprotkb/Q9W0N6" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q9W0N6", "url": "https://www.uniprot.org/uniprotkb/Q9W0N6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9W0N6", "url": "https://www.uniprot.org/uniprotkb/Q9W0N6" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9W0N6", "url": "https://www.uniprot.org/uniprotkb/Q9W0N6" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "Q9W0N6", "url": "https://www.uniprot.org/uniprotkb/Q9W0N6" } ], "pmid": "" }, { "name": "ER to Golgi transport vesicle membrane", "id": "GO:0012507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012507", "evidence": [ { "database": "UniProtKB", "id": "Q9W0N6", "url": "https://www.uniprot.org/uniprotkb/Q9W0N6" } ], "pmid": "" }, { "name": "clathrin-coated vesicle", "id": "GO:0030136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030136", "evidence": [ { "database": "UniProtKB", "id": "Q9W0N6", "url": "https://www.uniprot.org/uniprotkb/Q9W0N6" } ], "pmid": "" }, { "name": "SNARE complex", "id": "GO:0031201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031201", "evidence": [ { "database": "UniProtKB", "id": "Q9W0N6", "url": "https://www.uniprot.org/uniprotkb/Q9W0N6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "Q9W0N6", "url": "https://www.uniprot.org/uniprotkb/Q9W0N6" } ], "pmid": "" }, { "name": "macroautophagy", "id": "GO:0016236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016236", "evidence": [ { "database": "UniProtKB", "id": "Q9W0N6", "url": "https://www.uniprot.org/uniprotkb/Q9W0N6" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi 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apparatus", "id": "GO:0048280", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048280", "evidence": [ { "database": "UniProtKB", "id": "Q9W0N6", "url": "https://www.uniprot.org/uniprotkb/Q9W0N6" } ], "pmid": "" }, { "name": "intra-Golgi vesicle-mediated transport", "id": "GO:0006891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006891", "evidence": [ { "database": "UniProtKB", "id": "Q9W0N6", "url": "https://www.uniprot.org/uniprotkb/Q9W0N6" } ], "pmid": "" }, { "name": "Golgi to vacuole transport", "id": "GO:0006896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006896", "evidence": [ { "database": "UniProtKB", "id": "Q9W0N6", "url": "https://www.uniprot.org/uniprotkb/Q9W0N6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "SNARE binding", "id": "GO:0000149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000149", "evidence": [ { "database": "UniProtKB", "id": "Q9W0N6", "url": "https://www.uniprot.org/uniprotkb/Q9W0N6" } ], "pmid": "" }, { "name": "SNAP receptor activity", "id": "GO:0005484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005484", "evidence": [ { "database": "UniProtKB", "id": "Q9W0N6", "url": "https://www.uniprot.org/uniprotkb/Q9W0N6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 30, "end_pos": 32, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9W0N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W0N6" }, { "id": "SM00397", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00397" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "T-SNARE coiled-coil homology", "eco_id": "ECO_0000259", "start_pos": 123, "end_pos": 190, "start_aa": "Arg", "end_aa": "Met", "glycosite_overlap": "" } ], 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"https://www.uniprot.org/uniprotkb/Q9W0R3" } ] }, { "name": "Meg", "type": "synonym", "evidence": [ { "id": "NP_001163309", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001163309" }, { "id": "Q9W0R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W0R3" } ] }, { "name": "PTP-meg", "type": "synonym", "evidence": [ { "id": "NP_001163309", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001163309" }, { "id": "Q9W0R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W0R3" } ] }, { "name": "PTPMEG", "type": "synonym", "evidence": [ { "id": "NP_001163309", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001163309" }, { "id": "Q9W0R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W0R3" } ] }, { "name": "Ptpmeg", "type": "synonym", "evidence": [ { "id": "NP_001163309", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001163309" } ] }, { "name": "anon-WO0118547.211", "type": "synonym", "evidence": [ { "id": "NP_001163309", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001163309" }, { "id": "Q9W0R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W0R3" } ] }, { "name": "dMEG1", "type": "synonym", "evidence": [ { "id": "NP_001163309", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001163309" }, { "id": "Q9W0R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W0R3" } ] }, { "name": "dPtpmeg", "type": "synonym", "evidence": [ { "id": "NP_001163309", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001163309" }, { "id": "Q9W0R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W0R3" } ] }, { "name": "dptpmeg", "type": "synonym", "evidence": [ { "id": "NP_001163309", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001163309" }, { "id": "Q9W0R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W0R3" } ] }, { "name": "ptmpeg", "type": "synonym", "evidence": [ { "id": "NP_001163309", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001163309" }, { "id": "Q9W0R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W0R3" } ] }, { "name": "ptpmeg", "type": "synonym", "evidence": [ { "id": "NP_001163309", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001163309" }, { "id": "Q9W0R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W0R3" } ] }, { "name": "scc", "type": "synonym", "evidence": [ { "id": "NP_001163309", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001163309" }, { "id": "Q9W0R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W0R3" } ] } ], "protein_names": [ { "name": "Tyrosine-protein phosphatase", "type": "recommended", "evidence": [ { "id": "Q9W0R3", "database": "UniProtKB", "url": 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"database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-5675221", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-5675221", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001163309", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001163309", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "10684", "url": "https://www.rhea-db.org/rhea/10684", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q9W0R3", "url": "https://www.uniprot.org/uniprotkb/Q9W0R3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W0R3-1", "url": "https://www.uniprot.org/uniprotkb/Q9W0R3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFERFRLNNLTRTFRLRGGGPELARDKKTPQRQQCVTVLFLDDITHTFRIEKRAKGSELLDQVFQYLELSERDYFGLLFPQKPGDVVRWVDAQKQFKKQCSSVSLDNDAVPLLEFRVKFFVSDPSRLQEEFTRYQFYLQIKRNILLGKLPCSSNTQCLLASYTVQSELGDFNALEHQPGYLSGMQLLCDQTTEAERKVGELHKLHRGQLPADAEYNYLEHAKRLELYGIDLHRATDSNGKELQLGVSAVGLLVFQHSLRVNTFSWSKMVKVSFKRKDFFIQLRREPSENYDTLLGFGMSSHKHAKALWKSCVEHHSFFRLKRPHRLSRFLNISLGSKFYYSGRTELQAVQESKQRGRIHKVFVRSPSKRLLGAAGGVGTSGSSGGTPMQQHSGSESANSHNNGKPAGAGTILTITKTSRPHDNKVTSKEADSMPRKAWEQQSDEYDIQLDVGFIEQCTRRFESASPSPMPPAYSSGQHSPILLPTTIADAVGHQQPESGSDLITIRLQADEQGRYGFNVKGGVDLSLPVQVSKVVPHTPADRCTPRVCEGDEVLMINGRDVHGLRHEQVVAMIRDCRHQASGELLLTVRPQRSAPLLLEEEPLYQYVPESDEIGSHSNLLDGDALFTQSLLLLSDGLASGALLAQYELMYRKNPDLAITEARKPANAPKNRYRDISPYDCTRVSLVNSLTGDYINANYVNMEIPGGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYWPVTGEELQLAEGFSVRCLSEKPDETGSFVFREFVLKDKHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAARNRTLLQEIEESLKQVRLMDADADADENGGLMRERKCAASNGATPEDETPVSTSVHQCISAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECICAAYMKISRSSAAINDDED", "length": 974, "header": "tr|Q9W0R3-1|Q9W0R3_DROME Isoform 1 of Tyrosine-protein phosphatase OS=Drosophila melanogaster OX=7227 GN=Ptpmeg PE=3 SV=3 CANONICAL=Q9W0R3-1" }, "isoforms": [ { "isoform_ac": "Q9W0R3-1", "url": "https://www.uniprot.org/uniprotkb/Q9W0R3/entry#Q9W0R3-1", "sequence": { "sequence": "MFERFRLNNLTRTFRLRGGGPELARDKKTPQRQQCVTVLFLDDITHTFRIEKRAKGSELLDQVFQYLELSERDYFGLLFPQKPGDVVRWVDAQKQFKKQCSSVSLDNDAVPLLEFRVKFFVSDPSRLQEEFTRYQFYLQIKRNILLGKLPCSSNTQCLLASYTVQSELGDFNALEHQPGYLSGMQLLCDQTTEAERKVGELHKLHRGQLPADAEYNYLEHAKRLELYGIDLHRATDSNGKELQLGVSAVGLLVFQHSLRVNTFSWSKMVKVSFKRKDFFIQLRREPSENYDTLLGFGMSSHKHAKALWKSCVEHHSFFRLKRPHRLSRFLNISLGSKFYYSGRTELQAVQESKQRGRIHKVFVRSPSKRLLGAAGGVGTSGSSGGTPMQQHSGSESANSHNNGKPAGAGTILTITKTSRPHDNKVTSKEADSMPRKAWEQQSDEYDIQLDVGFIEQCTRRFESASPSPMPPAYSSGQHSPILLPTTIADAVGHQQPESGSDLITIRLQADEQGRYGFNVKGGVDLSLPVQVSKVVPHTPADRCTPRVCEGDEVLMINGRDVHGLRHEQVVAMIRDCRHQASGELLLTVRPQRSAPLLLEEEPLYQYVPESDEIGSHSNLLDGDALFTQSLLLLSDGLASGALLAQYELMYRKNPDLAITEARKPANAPKNRYRDISPYDCTRVSLVNSLTGDYINANYVNMEIPGGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYWPVTGEELQLAEGFSVRCLSEKPDETGSFVFREFVLKDKHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAARNRTLLQEIEESLKQVRLMDADADADENGGLMRERKCAASNGATPEDETPVSTSVHQCISAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECICAAYMKISRSSAAINDDED", "length": 974, "header": "tr|Q9W0R3-1|Q9W0R3_DROME Isoform 1 of Tyrosine-protein phosphatase OS=Drosophila melanogaster OX=7227 GN=Ptpmeg PE=3 SV=3 CANONICAL=Q9W0R3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W0R3", "url": "https://www.uniprot.org/uniprotkb/Q9W0R3" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W0R3", "url": "https://www.uniprot.org/uniprotkb/Q9W0R3" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W0R3", "url": "https://www.uniprot.org/uniprotkb/Q9W0R3" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W0R3", "url": "https://www.uniprot.org/uniprotkb/Q9W0R3" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W0R3", "url": "https://www.uniprot.org/uniprotkb/Q9W0R3" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W0R3", "url": "https://www.uniprot.org/uniprotkb/Q9W0R3" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W0R3", "url": "https://www.uniprot.org/uniprotkb/Q9W0R3" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W0R3", "url": "https://www.uniprot.org/uniprotkb/Q9W0R3" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W0R3", "url": "https://www.uniprot.org/uniprotkb/Q9W0R3" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W0R3", "url": "https://www.uniprot.org/uniprotkb/Q9W0R3" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W0R3", "url": "https://www.uniprot.org/uniprotkb/Q9W0R3" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG1228", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG1228", "resource": "KEGG Pathway" }, { "id": "R-DME-182971", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-182971", "resource": "Reactome", "description": "EGFR downregulation" }, { "id": "R-DME-5675221", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-5675221", "resource": "Reactome", "description": "Negative regulation of MAPK pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8D0HUI4-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type", "gene_name": "PTPN4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTSRFRLPAGRTYNVRASELARDRQHTEVVCNILLLDNTVQAFKVNKQEQGQVLLDVVFKHLDLTERDYFGLQLADDSSDNPRWLDPNKPIRKQLKRGSPYSLNFRVKFFVSDPNKLQEEYTRYQYFLQIKQDILTGRLPCPYNTAALLASFAVQSELGDYNQTENLPGYLSDYSFIPNQPQDFEKEIAKLHQQHTGLSPAEAEFNYLNTARTLELYGVEFHYARDQSNNEIMIGVMSGGILIYMNRERMNSFPWLKIVKISFKCKQFFIQLRKELHESRETLLGFNMVNYRACKNLWKACVEHHTFFRLDRPLPPQKNFFAHYFTLGSKFRYCGRTEVQSVQYGKEKANKDRVFARSPSKPLARKLMDWEVVSRNSLSDDRLETQSLPSRSPPGTPNHRNSAFTQEGTRLRPSSVGHLVDHAVHTSPSEAFVNHRSPSSTQANSIVLESSPSQETPEDGQPPALPPKQSKKNSWNQIHYSHSQQDLENHIHETFDVPSSPEKSIPNGGVPHDNLVLIRMKPDENGRFGFNVKGGCDQKMPVIVSRVAPGTPADLCVPRLNEGDQVVLINGRDIAEHTHDQVVLFIKASCEKHSGELVLLVRPNAVYDVVEEKLENEPDFQYIPEKAPLDSGHQDDHSLRESMIQLAEGLITGTVLTQFDQLYRKKPGMTMSCAKLPQNISKNRYRDISPYDATRVILKGNEDYINANYINMEIPSSRIINQYIACQGPLPHTCTDFWQMTWEQGSSMVVMLTTQVERGRVKCHQYWPEPTGSSSYGCYQVTCHSEEGNTAYVFRKMTLFNQEKNESRQLTQIQYIAWPDHGVPDDSSDFLDFVCHVRNKRAGKEEPIVVHCSAGIGRTGVLITMETAMCLIECNQPVYPLDIVRTMRDQRAMMIQTPSQYRFVCEAILKVYEEGFVKPLTTSSNK", "length": 926 }, "evidence": [ { "id": "Q9W0R3", "url": "https://omabrowser.org/oma/group/Q9W0R3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5YBL2-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type", "gene_name": "Ptpn3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTSRLRALGGRINNIRTSELPKEKTRSEVTCSIRFLDGLVQTFKVNKQDLGQSLLDMAYGHLGVTEKEYFGLQHGDDPVDSPRWLEASKPLRKQLKGGLPCILHFRVRYFIPDPNTLQQEQTRHLYFLQLKMDVCEGRLTCPLNSAVVLASYAVQSHIGDFNSSIHHPGYLADSQFIPDQNDDFLSKVESLHEQHSGLKQSEAESCYINIARTLDFYGVELHGGRDLHNLDLMIGIASAGIAVYRKYICTSFYPWVNILKISFKRKKFFIHQRQKQAESREHIVAFNMLNYRSCKNLWKSCVEHHSFFQAKKLLPQEKNVLSQYWTLGSRNPKKSVNNQYCKKVIGGMVWNPVMRRSLSVERLETKSLPSRSPPITPNWRSPRLRHEIRKPRHSSADNLANEMTYITETEDVFYTYKGSLSPKDSDSEVSQNHSPHRGSLSENNPAQSCLTQKSSSSVSPCSNAPGSFSPDGVDQQFLEDYHKVTKGGSIEEASQYYCDKNDDGDGYLVLIRITPDKEGRFGFNLKGGVDQKMPLVVSRINPESPADTCMPKLNEGDQIVLINGRDISEHTHDQVVMFIKASRESHSRELALVIRRKAVRSLAEIRSEDELSQLFPEAMFPACPEGGDSLEGSMELLKKGLESGTVLIQFEQLYRKKPGLAVTFAKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHTCAQFWQVVWDQKLSLVVMLTTLTERGRTKCHQYWPDPPDIMDHGIFHIQCQAEDCTIAYVSREMLVTNTETGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVKYVRSLRVGGEPALVHCSAGIGRTGVLVTMETAMCLIERNLPVYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRVYEEGLVQTLDPS", "length": 913 }, "evidence": [ { "id": "RGD:1311363", "url": "https://alliancegenome.org/gene/RGD:1311363#orthology", "database": "AGR" }, { "id": "HGNC:9655", "url": "https://alliancegenome.org/gene/HGNC:9655#orthology", "database": "AGR" }, { "id": "MGI:105307", "url": "https://alliancegenome.org/gene/MGI:105307#orthology", "database": "AGR" }, { "id": "FB:FBgn0261985", "url": "https://alliancegenome.org/gene/FB:FBgn0261985#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0Z920-1", "protein_name": "Tyrosine-protein phosphatase", "gene_name": "PTPN4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLREEDAAGARSCSLEFQFWRKLTLTLSPPLPQLPQDSDQHKCVLTPEKHLSTMWRDPVWTVMTARFRLPAGRTYNVRASELARDRQHTEVVCNILLLDNTVQAFRVNKHDQGQVLLDIVFKHLDLTERDYFGLQLADESTDNPRWLDPNKPIRKQLKRGSPHSLNLRVKFFVSDPNKLQEEYTRYQYFLQIKQDILTGRLPCPYNTAALLASYAVQSELGDYNHLENLPGYLSDYSFIPGQPQDFEKEIAKLHQQHIGLSPAEAEFNYLNTARTLELYGVELHYARDQSNNEIMIGVMSGGILIFKNRVRINTFPWLKIVKISFKCKQFFVQLRKELHESRETLLGFNMVNYRACKNLWKACVEHHTFFRLDRPLPPQKNFFAHYFTLGSKFRYCGRTEVQSVQYGKERANKDRVFARSPSKPLARKLMSGMDWEVVSRNSLSDDRLETQSLPSRSPPGTPNHRNSAFTQEGARLRPSSVGHLVDHVVHTSPSEVFVNHRSPSSTQANSIILESSPSQETPIDGQPPALPPKQFKKNSWNQIHHSHSQQELDNHINETFDVPASPEKSTPNGGVPHDNLVMIRMKPDENGRFGFNVKGGYDQKMPVIVSRVAPGTPADLCVPRLNEGDQVVLINGRDIAEHTHDQVVMFIKASCERHSGELVLLVRPNAVYDVVEEKLESEPDFQYIPEKSPLDGVHQDDNALRESMIQLAEGLITGTVLAQFDQLYRKKPGMTMSCARLPQNISKNRYRDISPYDATRVILKSNEDYINANYINMEIPSSTIINQYIACQGPLPNTCPDFWQMTWEQGSSMVVMLTTQVERGRVKCHQYWPEPSGSSSYGNFQITCHSEEGNPAYVFREMTLTNLEKEESRQLTQIQYIAWPDHGVPDDSSDFLDFVCLVRKKRAGREEPVVVHCSAGIGRTGVLITMETAMCLIECNQPVYPLDIVRTMRDQRAMMIQTPSQYRFVCEAILKVYEEGFIKPLQASPHK", "length": 991 }, "evidence": [ { "id": "Q9W0R3", "url": "https://omabrowser.org/oma/group/Q9W0R3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0AB32U039-1", "protein_name": "Tyrosine-protein phosphatase", "gene_name": "ptpn4a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTARFRLPAGRSYNVRTTELARDRQRTEVVCNILLLDNTVQPFKVNKHDQGQILLDAVFKHLELTERDYFGLHLADEPSDSPRWLDPNKPIRKQLKRGSPHHLNFRVKFFVSDPNKLQEEYTRYQYFLQIKQDILSGRLPCPHNTAALLASYAVQSELGDYSEAENLPGYLSEFFFIPNQPQGFEKDVAKHHQQHNGLNPAQSEFNYLNTARTLDLYGVELHYARDQSNTEIYVGVLSAGIGIYKNRVRINYFPWLKIVKISFKCKQFFIQLRKEAHDTRDTLLGFNMVNYRACKNLWKTCVEHHTFFRLDRPVPPQKNFFAHYFSLGSRFRYCGRTEAQSVQYGKEKGIKDRVFARSPSKPLARKLMGVTDWEAVSRNSLSEERLETRSLPTRSPPGTPNHNSLFVQEGPRLRPSSMGHLVDHVIHASPSLPVFSNHKSASSTQANSISLESTPSPEGVEGPPPALPPKQSRKNLSQLILSHSQQDLDNHINEMYDVPTATDKVMPNGVVPHDNLVLIKMKPDENGRFGFNVKGGSDQKMPIIVSRVAPGTSADLCVPRLNEGDQVVLINGREIAEHSHDQVVMFIKASCESHSGELILLVRPNAIYDVVEEKLETEPDFQYIPEKSPTDPSHLDQDAWRDSMLYLKEGLNSGTILAQFDQLYRKRPGMTMSCAKLPQNISKNRYRDISPYDATRVILKGTEDYINANYINMEIPACSLINRYIACQGPLPNTCSDFWQMTWEQGSSMVVMLTTQVERGRVKCHQYWPNPSGSATYGGFQISCQTEEGNSAFLVREITLTHIESGESRELTQIQYLAWPDHGVPDDSTDFLDFVALVRNKRAGKDEPVVVHCSAGIGRTGVLITMETAMCLMECSQPVFPLEIVRTMRDQRAMMIQTPSQFKFVCEAILKVYEEGLVKPLKSILYESN", "length": 929 }, "evidence": [ { "id": "HGNC:9656", "url": "https://alliancegenome.org/gene/HGNC:9656#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030616-449", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030616-449#orthology", "database": "AGR" }, { "id": "MGI:1099792", "url": "https://alliancegenome.org/gene/MGI:1099792#orthology", "database": "AGR" }, { "id": "RGD:620712", "url": "https://alliancegenome.org/gene/RGD:620712#orthology", "database": "AGR" }, { "id": "FB:FBgn0261985", "url": "https://alliancegenome.org/gene/FB:FBgn0261985#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A2ALK8-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 3", "gene_name": "Ptpn3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSRLRALGGRINNTRTSELPKEKTRSEVICSIRFLDGLVQTFKVNKQDLGQSLLDMAYGHLGVTEKEYFGLQHGDDPVDSPRWLEASKPLRKQLKGGFPCTLHFRVRYFIPDPNTLQQEQTRHLYFLQLKMDVCEGRLTCPLNSAVVLASYAVQSHFGDFNSSIHHPGYLADSQFIPDQNDDFLSKVESLHEQHSGLKQSEAESCYINIARTLDFYGVELHGGRDLHNLDLMIGIASAGIAVYRKYICTSFYPWVNILKISFKRKKFFIHQRQKQAESREHIVAFNMLNYRSCKNLWKSCVEHHSFFQAKKLLPQEKNVLSQYWTLGSRNPKKSVNNQYCKKVIGGMVWNPVMRRSLSVERLETKSLPSRSPPITPNWRSPRLRHEIRKPRHSSADNLANEMTYITETEDVFYTYKGPLSPKDSDSEVSQNHSPHRESLSENNPAQSCLTQKSSSSVSPSSNAPGSCSPDGVDQRFLEDYHKVTKGGFVEDASQYYCDKSDDGDGYLVLIRITPDEEGRFGFNLKGGVDQKMPLVVSRINPESPADTCMPKLNEGDQIVLINGRDISEHTHDQVVMFIKASRESHSRELALVIRRKAVRSLAEIRSEDELSQLFPEAMFPACPEGGDSLEGSMELLKKGLESGTVLIQFEQLYRKKPGLAVSFAKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEMPAANLVNKYIATQGPLPNTCAQFWQVVWDQKLSLVVMLTTLTERGRTKCHQYWPDPPDIMDHGIFHIQCQTEDCTIAYVSREMLVTNTETGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVKYVRSLRVDGEPALVHCSAGIGRTGVLVTMETAMCLIERNLPVYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRVYEEGLVQRLDPS", "length": 913 }, "evidence": [ { "id": "RGD:1311363", "url": "https://alliancegenome.org/gene/RGD:1311363#orthology", "database": "AGR" }, { "id": "HGNC:9655", "url": "https://alliancegenome.org/gene/HGNC:9655#orthology", "database": "AGR" }, { "id": "MGI:105307", "url": "https://alliancegenome.org/gene/MGI:105307#orthology", "database": "AGR" }, { "id": "FB:FBgn0261985", "url": "https://alliancegenome.org/gene/FB:FBgn0261985#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1QFY3-1", "protein_name": "Tyrosine-protein phosphatase", "gene_name": "ptpn4b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTARFRLPAGRSYDVGALEEARERQHAQVECNVLLLDNTVQTFRVNKQDQGQILLDVVYKHLELTERDYFGLQLADDTSDTQRWLDPNKPVRKQLKRPSPHNLRFRVKFFVGDPGKLQEEYTRYLYFLQLKQDILSGRLPCPQNTAVLLASYAVQAELGDYSHSEHLSGYLSEYSFIPNPPQDFEKEVAKLHQEHNGLTPAQSEFNYLNAARTLELYGVELHYARDHCNTEIYVGVLSAGISVYKDRVRVNHFPWFKIVKISFKSKQFFIQLRKELTECRESLLGFNMMNYRACKNLWKSCVENHTFFRLERPVPPERNLFLHYFTLGSKFRYCGRTEAQSVQYGKERGNKNRVFARSPSKPLVRRLMSGLDWETVSRNSLSDDRLETQSLPNRSPPDSPDHSNSVFTTEGARIRPSSIGHLVDHVIDDSPCQTFTNHKSASSTQANSISLDSTPSPDVTTDEQPPALPPKQFRKDPLNHNGRSQSQHELDDHDHLSELYNVPAASGKSMNGAVPHDNLVLIKMRPDENGRFGFNVKGGVDQRMPIIVSRVAPGTPADMCVPRLNEGDQVVLINGRDISDHTHDDVVMIIKASCEDQSGELILLVRPNAIYDVDEEQEKLDLEPDFQYIPEACGLESHSEADSLRSSIQLLRDGLASGTVPAQFDQLYRKRPGMSMSCARLPQNVSKNRYRDISPYDSTRVVLKGTEDYINANFINMDVPSKGEVRRYIACQGPLPGTCSDFWQMVWEQSAALVVMLTTQVERGRVKCHQYWPNVSASGTYGGFQVTCVSEEGNSAYLLRDLTLTHLESKEERQICQMQYLAWPDHGVPDDSSDFLNFVSQVRSKRADGPEPVVVHCSAGIGRTGVLITMETAMCLIEGGQSVYPLDIVRTMRDQRAMMIQTPSQYRFVCEAILKVYDEEIVKPFETELPVEKEE", "length": 935 }, "evidence": [ { "id": "HGNC:9656", "url": "https://alliancegenome.org/gene/HGNC:9656#orthology", "database": "AGR" }, { "id": "Q9W0R3", "url": "https://omabrowser.org/oma/group/Q9W0R3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QLN8-1", "protein_name": "protein-tyrosine-phosphatase", "gene_name": "ptpn3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTSPWCMLGNKITALGRADLSKHTHMPRSGLLCLVLFPDGTTQNFTVNKHDAGHLLFDLACEHLNIVEKQYFSMQISEDTSSSPRWLDPNKPFKKQLKGSPPFFLMFRVRFFISDPNSLQHEQTRHFYFLQIRKDICEGRLKCPLSSAVVLASYSVQSELGDYNPETPTGYLSKTHFIPEQDQEFLLKVESLHPQHKGLSQSDAELCYLNTARTLDLYGVELHHAQDASNPAVWVGITSGGVALFCHLICSSFFPWINIIKISFKRKRFFVHLRRKHGELGHHVVSLSMPNSRACKNLWRSCVDHHTFYNRKPSHSASKLSSIPLYRKLVGEQMLNPMVRSSSVEQLETKSLPSRSPPNTPNWRSPRVRHDFRNPRPSSVDNLTNEMSYVTESEDVFYTYRKPQEEERRSGSWSHGDDITIEEDDLHVWDKSVTADGDLLLVRISPDQDGKFGFNVKGGVDQKMPLAISHVNLASPAGRCVPPLMEGDQVLLINGRDISEHTHQQVVMFIKASRESHSKELALLVRRKGVSLRVEPTLQLGLTLPGEISPLSTHPSGETLEESMARLEKGLVTGTLLLHFEKLYRKKEGMLMSCAKQSENMDKNRYKDVLPYDITRVVLQEEGDDYINASHVKTEPAGCVLQYIAAQGPLPHTCTHFWRSVWEQDVNVIIMLTTLTERGRTKCHQYWPHPPEVRDYGYLQVCCHSEECNLAYVTRQLTLTNTQSGQQRSITHLQYVAWPDHGVPEDSSDFLDFVKSVRSMRQESVPLMVHCSAGIGRTGVLITMETAMTLMEKEKPVYPLEVITLMREQRAMLVQTSCQFTFVCEAILRVYREKVKPNS", "length": 839 }, "evidence": [ { "id": "HGNC:9655", "url": "https://alliancegenome.org/gene/HGNC:9655#orthology", "database": "AGR" }, { "id": "MGI:105307", "url": "https://alliancegenome.org/gene/MGI:105307#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3V6B9-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type", "gene_name": "Ptpn4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTARFRLPAGRTYNVRASELARDRQHTEVVCNILLLDNTVQAFRVNKHDQGQVLLDIVFKHLDLTERDYFGLQLADDSTDNPRWLDPNKPIRKQLKKLFLLILGGSPYNLNFRVKFFVSDPNKLQEEYTRYQYFLQIKQDILTGRLSCPCNTAALLASFAVQSELGDYNQSENLAGYLSDYSFIPNQPQDFEKEIAKLHQQHIGLSPAEAEFNYLNTARTLELYGVEFHYARDQSNNEILIGVMSGGILIYKNRVRMNTFLWLKIVKISFKCKQFFIQLRKELHESRETLLGFNMVNYRACKTLWKACVEHHTFFRLDRPLPPQKNFFAHYFTLGSKFRYCGRTEVQSVQYGKEKANKDRVFARSPSKPLARKLMDWEVVSRNSLSDDRLETQSLPSRSPPGTPNHRNSSFTQEGTRVRPSSVGHLVDHVVHTSPSEDFVSQRSPSSTQANSIVLESSPSQETPEDGQPPALPPKQSKKNSWNQIHFSHSQQDLVNHTNESFDVPSSPEKSTPNGGIPHDNLVLIKMKPDENGRFGFNVKGGYDQKMPVIVSRVAPGTPADLCVPRLNEGDQVVLINGRDIAEHTHDQVVLFIKASCERHSGELVLLVRPNAVYDVVEEKLESEPDFQYIPEKAPLDSVHQDDHSLRESMIQLAEGLITGTVLAQFDQLYRKKPGMTMSCAKLPQNISKNRYRDISPYDATRVLLKGNEDYINANYINMEISSSSIINQYIACQGPLPHTCKDFWQMTWEQGSSMVVMLTTQVERGRVKCHQYWPEPSGSSSYGCYQVTCHSEEGNPAYIFRKMTLFNQEKNESRQLTQIQYTAWPDHGVPDDSSDFLDFVCHVRNKRAGKEEPIIVHCSAGIGRTGVLITMETAMCLIECNQPVYPLDIVRTMRDQRAMMIQTPSQYRFVCEAILKVYEEGFVKPLTTSSNK", "length": 933 }, "evidence": [ { "id": "HGNC:9656", "url": "https://alliancegenome.org/gene/HGNC:9656#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030616-449", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030616-449#orthology", "database": "AGR" }, { "id": "MGI:1099792", "url": "https://alliancegenome.org/gene/MGI:1099792#orthology", "database": "AGR" }, { "id": "RGD:620712", "url": "https://alliancegenome.org/gene/RGD:620712#orthology", "database": "AGR" }, { "id": "FB:FBgn0261985", "url": "https://alliancegenome.org/gene/FB:FBgn0261985#orthology", "database": "AGR" }, { "id": "Q9W0R3", "url": "https://omabrowser.org/oma/group/Q9W0R3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P26045-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 3", "gene_name": "PTPN3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSRLRALGGRINNIRTSELPKEKTRSEVICSIHFLDGVVQTFKVTKQDTGQVLLDMVHNHLGVTEKEYFGLQHDDDSVDSPRWLEASKAIRKQLKGGFPCTLHFRVRFFIPDPNTLQQEQTRHLYFLQLKMDICEGRLTCPLNSAVVLASYAVQSHFGDYNSSIHHPGYLSDSHFIPDQNEDFLTKVESLHEQHSGLKQSEAESCYINIARTLDFYGVELHSGRDLHNLDLMIGIASAGVAVYRKYICTSFYPWVNILKISFKRKKFFIHQRQKQAESREHIVAFNMLNYRSCKNLWKSCVEHHTFFQAKKLLPQEKNVLSQYWTMGSRNTKKSVNNQYCKKVIGGMVWNPAMRRSLSVEHLETKSLPSRSPPITPNWRSPRLRHEIRKPRHSSADNLANEMTYITETEDVFYTYKGSLAPQDSDSEVSQNRSPHQESLSENNPAQSYLTQKSSSSVSPSSNAPGSCSPDGVDQQLLDDFHRVTKGGSTEDASQYYCDKNDNGDSYLVLIRITPDEDGKFGFNLKGGVDQKMPLVVSRINPESPADTCIPKLNEGDQIVLINGRDISEHTHDQVVMFIKASRESHSRELALVIRRRAVRSFADFKSEDELNQLFPEAIFPMCPEGGDTLEGSMAQLKKGLESGTVLIQFEQLYRKKPGLAITFAKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHTCAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPDPPDVMNHGGFHIQCQSEDCTIAYVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVDSEPVLVHCSAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRVYEEGLVQMLDPS", "length": 913 }, "evidence": [ { "id": "RGD:1311363", "url": "https://alliancegenome.org/gene/RGD:1311363#orthology", "database": "AGR" }, { "id": "HGNC:9655", "url": "https://alliancegenome.org/gene/HGNC:9655#orthology", "database": "AGR" }, { "id": "MGI:105307", "url": "https://alliancegenome.org/gene/MGI:105307#orthology", "database": "AGR" }, { "id": "FB:FBgn0261985", "url": "https://alliancegenome.org/gene/FB:FBgn0261985#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P29074-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 4", "gene_name": "PTPN4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSRFRLPAGRTYNVRASELARDRQHTEVVCNILLLDNTVQAFKVNKHDQGQVLLDVVFKHLDLTEQDYFGLQLADDSTDNPRWLDPNKPIRKQLKRGSPYSLNFRVKFFVSDPNKLQEEYTRYQYFLQIKQDILTGRLPCPSNTAALLASFAVQSELGDYDQSENLSGYLSDYSFIPNQPQDFEKEIAKLHQQHIGLSPAEAEFNYLNTARTLELYGVEFHYARDQSNNEIMIGVMSGGILIYKNRVRMNTFPWLKIVKISFKCKQFFIQLRKELHESRETLLGFNMVNYRACKNLWKACVEHHTFFRLDRPLPPQKNFFAHYFTLGSKFRYCGRTEVQSVQYGKEKANKDRVFARSPSKPLARKLMDWEVVSRNSISDDRLETQSLPSRSPPGTPNHRNSTFTQEGTRLRPSSVGHLVDHMVHTSPSEVFVNQRSPSSTQANSIVLESSPSQETPGDGKPPALPPKQSKKNSWNQIHYSHSQQDLESHINETFDIPSSPEKPTPNGGIPHDNLVLIRMKPDENGRFGFNVKGGYDQKMPVIVSRVAPGTPADLCVPRLNEGDQVVLINGRDIAEHTHDQVVLFIKASCERHSGELMLLVRPNAVYDVVEEKLENEPDFQYIPEKAPLDSVHQDDHSLRESMIQLAEGLITGTVLTQFDQLYRKKPGMTMSCAKLPQNISKNRYRDISPYDATRVILKGNEDYINANYINMEIPSSSIINQYIACQGPLPHTCTDFWQMTWEQGSSMVVMLTTQVERGRVKCHQYWPEPTGSSSYGCYQVTCHSEEGNTAYIFRKMTLFNQEKNESRPLTQIQYIAWPDHGVPDDSSDFLDFVCHVRNKRAGKEEPVVVHCSAGIGRTGVLITMETAMCLIECNQPVYPLDIVRTMRDQRAMMIQTPSQYRFVCEAILKVYEEGFVKPLTTSTNK", "length": 926 }, "evidence": [ { "id": "HGNC:9656", "url": "https://alliancegenome.org/gene/HGNC:9656#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030616-449", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030616-449#orthology", "database": "AGR" }, { "id": "MGI:1099792", "url": "https://alliancegenome.org/gene/MGI:1099792#orthology", "database": "AGR" }, { "id": "RGD:620712", "url": "https://alliancegenome.org/gene/RGD:620712#orthology", "database": "AGR" }, { "id": "FB:FBgn0261985", "url": "https://alliancegenome.org/gene/FB:FBgn0261985#orthology", "database": "AGR" }, { "id": "Q9W0R3", "url": "https://omabrowser.org/oma/group/Q9W0R3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9WU22-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 4", "gene_name": "Ptpn4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTARFRLPAGRTYNVRASELARDRQHTEVVCNILLLDNTVQAFRVNKHDQGQVLLDIVFKHLDLTERDYFGLQLADDSTDNPRWLDPNKPIRKQLKRGSPYNLNFRVKFFVSDPNKLQEEYTRYQYFLQIKQDILTGRLSCPCNTAALLASFAVQSELGDYNQSENLAGYLSDYSFIPNQPQDFEKEIAKLHQQHVGLSPAEAEFNYLNAARTLELYGVEFHYARDQSNNEILIGVMSGGILIYKNRVRMNTFLWLKIVKISFKCKQFFIQLRKELHESRETLLGFNMVNYRACKTLWKACVEHHTFFRLDRPLPPQKNFFAHYFTLGSKFRYCGRTEVQSVQYGKEKANKDRVFARSPSKPLARKLMDWEVVSRNSLSDDRLETQSLPSRSPPGTPNHRNSSFTQEATRVRPSSVGHLVDHVVHMSPSEDFVSQRSPSSTQANSIVLESSPSQETPEDGQPPALPPKQSKKNSWNQIHFSNSQQDLVTHTNESFDVPSSPEKSTPNGGIPHDNLVLIKMKPDENGRFGFNVKGGYDQKMPVIVSRVAPGTPADLCVPRLNEGDQVVLINGRDIAEHTHDQVVLFIKASCEKHSGELVLLVRPNAVYDVVEEKLESEPDFQYIPEKAPLDSVHQDDHSLRESMIQLAEGLITGTVLAQFDQLYRKKPGMTMSCAKLPQNISKNRYRDISPYDATRVLLKGNEDYINANYINMEIPSSSIINQYIACQGPLPHTCKDFWQMTWEQGSSMVVMLTTQVERGRVKCHQYWPEPSESSSYGCYQVTCHSEEGNPAYIFRKMTLFNQEKNESRQLTQIQYTAWPDHGVPDDSSDFLDFVCHVRDQRAGKEEPIIVHCSAGIGRTGVLITMETAMCLIECNQPVYPLDIVRTMRDQRAMMIQTPSQYRFVCEAILKVYEEGFVKPLTTSSNK", "length": 926 }, "evidence": [ { "id": "HGNC:9656", "url": "https://alliancegenome.org/gene/HGNC:9656#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030616-449", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030616-449#orthology", "database": "AGR" }, { "id": "MGI:1099792", "url": "https://alliancegenome.org/gene/MGI:1099792#orthology", "database": "AGR" }, { "id": "RGD:620712", "url": "https://alliancegenome.org/gene/RGD:620712#orthology", "database": "AGR" }, { "id": "FB:FBgn0261985", "url": "https://alliancegenome.org/gene/FB:FBgn0261985#orthology", "database": "AGR" }, { "id": "Q9W0R3", "url": "https://omabrowser.org/oma/group/Q9W0R3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9W0R3", "url": "https://www.uniprot.org/uniprotkb/Q9W0R3" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9W0R3", "url": "https://www.uniprot.org/uniprotkb/Q9W0R3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9W0R3", "url": "https://www.uniprot.org/uniprotkb/Q9W0R3" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "Q9W0R3", "url": "https://www.uniprot.org/uniprotkb/Q9W0R3" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9W0R3", "url": "https://www.uniprot.org/uniprotkb/Q9W0R3" } ], "pmid": "" }, { "name": "cell periphery", "id": "GO:0071944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071944", "evidence": [ { "database": "UniProtKB", "id": "Q9W0R3", "url": "https://www.uniprot.org/uniprotkb/Q9W0R3" } ], "pmid": "" }, { "name": "anchoring junction", "id": "GO:0070161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070161", "evidence": [ { "database": "UniProtKB", "id": "Q9W0R3", "url": "https://www.uniprot.org/uniprotkb/Q9W0R3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "animal organ morphogenesis", "id": "GO:0009887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009887", "evidence": [ { "database": "UniProtKB", "id": "Q9W0R3", "url": "https://www.uniprot.org/uniprotkb/Q9W0R3" } ], "pmid": "" }, { "name": "negative regulation of epidermal growth factor receptor signaling pathway", "id": "GO:0042059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042059", "evidence": [ { "database": "UniProtKB", "id": "Q9W0R3", "url": "https://www.uniprot.org/uniprotkb/Q9W0R3" } ], "pmid": "" }, { "name": "thermosensory behavior", "id": "GO:0040040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040040", "evidence": [ { "database": "UniProtKB", "id": "Q9W0R3", "url": "https://www.uniprot.org/uniprotkb/Q9W0R3" } ], "pmid": "" }, { "name": "axon extension involved in axon guidance", "id": "GO:0048846", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048846", "evidence": [ { "database": "UniProtKB", "id": "Q9W0R3", "url": "https://www.uniprot.org/uniprotkb/Q9W0R3" } ], "pmid": "" }, { "name": "mushroom body development", "id": "GO:0016319", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016319", "evidence": [ { "database": "UniProtKB", "id": "Q9W0R3", "url": "https://www.uniprot.org/uniprotkb/Q9W0R3" } ], "pmid": "" }, { "name": "central complex development", "id": "GO:0048036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048036", "evidence": [ { "database": "UniProtKB", "id": "Q9W0R3", "url": "https://www.uniprot.org/uniprotkb/Q9W0R3" } ], "pmid": "" }, { "name": "negative regulation of border follicle cell migration", "id": "GO:1903687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903687", "evidence": [ { "database": "UniProtKB", "id": "Q9W0R3", "url": "https://www.uniprot.org/uniprotkb/Q9W0R3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "cytoskeletal protein binding", "id": "GO:0008092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008092", "evidence": [ { "database": "UniProtKB", "id": "Q9W0R3", "url": "https://www.uniprot.org/uniprotkb/Q9W0R3" } ], "pmid": "" }, { "name": "non-membrane spanning protein tyrosine phosphatase activity", "id": "GO:0004726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004726", "evidence": [ { "database": "UniProtKB", "id": "Q9W0R3", "url": "https://www.uniprot.org/uniprotkb/Q9W0R3" } ], "pmid": "" }, { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "Q9W0R3", "url": "https://www.uniprot.org/uniprotkb/Q9W0R3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 331, "end_pos": 333, "annotation": "n_glycosylation_sequon" }, { "start_pos": 831, "end_pos": 833, "annotation": "n_glycosylation_sequon" }, { "start_pos": 944, "end_pos": 946, "annotation": "n_glycosylation_sequon" }, { "start_pos": 9, "end_pos": 11, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10684", "name": "", "equation": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P82890-1", "Q03019-1", "P35832-1", "P29349-4", "P35992-5", "Q05201-1", "Q6NN85-1", "Q86BN8-1", "P82891-1", "P16621-1", "O61722-1", "Q9W0G1-1", "P20483-1", "X2JEB8-1", "Q9VVW5-1", "P16620-1", "Q9VWF4-1", "Q9W4F5-1", "Q9W0R3-1", "M9PI51-1" ], "evidence": [ { "id": "10684", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10684" } ] }, { "id": "R-DME-8867047", "name": "PTPN3 dephosphorylates EPS15", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P04412-1", "Q9VSK2-1", "Q9W0R3-1" ], "evidence": [ { "id": "R-DME-8867047", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8867047" } ] }, { "id": "R-DME-8867654", "name": "PTPN3 binds p-T183,Y185 MAPK12", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O62618-1", "P83100-1", "O61443-1", "Q9W0R3-1" ], "evidence": [ { "id": "R-DME-8867654", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8867654" } ] }, { "id": "R-DME-8867658", "name": "PTPN3 dephosphorylates MAPK12", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [ "R-DME-8867650" ], "enzyme_list": [ "O62618-1", "P83100-1", "O61443-1", "Q9W0R3-1" ], "evidence": [ { "id": "R-DME-8867658", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8867658" } ] }, { "id": "R-DME-8868118", "name": "MAPK12 phosphorylates PTPN3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O62618-1", "P83100-1", "O61443-1", "Q9W0R3-1" ], "evidence": [ { "id": "R-DME-8868118", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8868118" } ] } ], "reaction_participants": [ { "participant_id": "R-DME-8867650", "participant_name": "PTPN3 [cytosol]", "crossref": [ { "id": "NP_001163310.2", "database": "RefSeq", "url": "" }, { "id": "Q9W0R3", "database": "UniProt", "url": "" }, { "id": "NP_001163309.2", "database": "RefSeq", "url": "" }, { "id": "NP_728522.2", "database": "RefSeq", "url": "" }, { "id": "NP_728523.2", "database": "RefSeq", "url": "" }, { "id": "FBgn0261985", "database": "FlyBase", "url": "" }, { "id": "NP_612031.3", "database": "RefSeq", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "M9PI51", "gene_name": "Dmel\\CG10089", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "M9PI51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9PI51" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "M9PI51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9PI51" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "M9PI51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9PI51" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "M9PI51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9PI51" } ] } ] }, { "uniprot_ac": "O61443", "gene_name": "p38b", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "O61443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O61443" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "O61443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O61443" } ] } ] }, { "uniprot_ac": "O61722", "gene_name": "PRL-1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O61722", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O61722" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O61722", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O61722" } ] } ] }, { "uniprot_ac": "O62618", "gene_name": "p38a", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "O62618", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O62618" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "O62618", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O62618" } ] } ] }, { "uniprot_ac": "P04412", "gene_name": "Egfr", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "P04412", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04412" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "P04412", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04412" } ] } ] }, { "uniprot_ac": "P16620", "gene_name": "Ptp69D", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P16620", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P16620" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P16620", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P16620" } ] } ] }, { "uniprot_ac": "P16621", "gene_name": "Lar", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P16621", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P16621" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P16621", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P16621" } ] } ] }, { "uniprot_ac": "P20483", "gene_name": "stg", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P20483", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20483" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P20483", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P20483" } ] } ] }, { "uniprot_ac": "P29349", "gene_name": "csw", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P29349", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P29349" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P29349", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P29349" } ] } ] }, { "uniprot_ac": "P35832", "gene_name": "Ptp99A", "activity": [ { "ec_number": "3.1.3.-", "activity": "", "evidence": [ { "id": "P35832", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35832" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P35832", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35832" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P35832", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35832" } ] } ] }, { "uniprot_ac": "P35992", "gene_name": "Ptp10D", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P35992", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35992" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P35992", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35992" } ] } ] }, { "uniprot_ac": "P82890", "gene_name": "primo-1", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "P82890", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P82890" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P82890", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P82890" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P82890", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P82890" } ] } ] }, { "uniprot_ac": "P82891", "gene_name": "primo-2", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "P82891", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P82891" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P82891", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P82891" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P82891", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P82891" } ] } ] }, { "uniprot_ac": "P83100", "gene_name": "p38c", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P83100", "database": 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"activity": "", "evidence": [ { "id": "Q05201", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05201" } ] } ] }, { "uniprot_ac": "Q6NN85", "gene_name": "ssh", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q6NN85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6NN85" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q6NN85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6NN85" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q6NN85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6NN85" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q6NN85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6NN85" } ] } ] }, { "uniprot_ac": "Q86BN8", 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"https://www.uniprot.org/uniprotkb/Q9W106/entry#names_and_taxonomy" } ] }, { "name": "3.4.21.-", "type": "synonym", "evidence": [ { "id": "Q9W106", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W106/entry#names_and_taxonomy" } ] }, { "name": "CG3589-PA", "type": "synonym", "evidence": [ { "id": "NP_611968", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611968" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_611968", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611968" } ] } ], "function": [ { "annotation": "Peroxisomal protease that mediates both the removal of the leader peptide from proteins containing a PTS2 target sequence and processes several PTS1-containing proteins. Catalyzes the processing of PTS1-proteins involved in the peroxisomal beta-oxidation of fatty acids.", "evidence": [ { "database": "UniProtKB", "id": "Q9W106", "url": "https://www.uniprot.org/uniprotkb/Q9W106#function" }, { "database": "UniProtKB", "id": "PIRNR037989", "url": "https://www.uniprot.org/uniprotkb/PIRNR037989#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W106", "url": "https://www.uniprot.org/uniprotkb/Q9W106" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG3589", "url": "https://www.uniprot.org/uniprotkb/Q9W106", "locus": { "chromosome": "2R", "start_pos": 24785542, "end_pos": 24783555, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0035065", "url": "https://www.ensemblgenomes.org/id/FBgn0035065" } ] } } ], "crossref": [ { "id": "FB:FBgn0035065", "url": "https://alliancegenome.org/gene/FB:FBgn0035065", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0035065", "url": "https://bgee.org/?page=gene&gene_id=FBgn0035065", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0035065", "url": "https://flybase.org/reports/FBgn0035065", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "37966", "url": "https://www.ncbi.nlm.nih.gov/gene/37966", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039245", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039245", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG3589", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3589", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GGPMFDQ", "url": "https://omabrowser.org/oma/group/GGPMFDQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W106", "url": "https://www.orthodb.org/?gene=Q9W106", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21004", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21004", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21004:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21004:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13365", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13365", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q9W106", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q9W106", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-DME-9033241", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9033241", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-9033500", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9033500", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_611968", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611968", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W106", "url": "https://www.uniprot.org/uniprotkb/Q9W106", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W106-1", "url": "https://www.uniprot.org/uniprotkb/Q9W106-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLKIRHALLEVTSPPAAKQSAIIINNELIISSGSILQPHLAVDGDKGAQNKAIVARLQRGQLLDVQNEEQEEDAQIRSLHFVATFDPQQRRPRPIAAPGSRQPHILSRFTAHPLYVFCANEVCRNLHHILLTADSGDAGEVLRSSFVVLGLRKPEKEKSFKRFLAHIANYLRYLQPMHTLDDVLVMCSPFGLENFYKTISIGKVSNVMGRSGCLFAISNALPLGCEGSAVFNNKLRLVGIVICTSFQRHHENVNLTLAANFGYLLRNFMEQLGMSTTAFQLSREPSSFAWERTIVVIESAGQQGTGTFIRVHNKRFILTCAHVVGQNIETVNCRAADREFQSEVIWCNPDSDKPFDLALLTAPQDVPEQCCVRLARSPATVGQMVYNAGFPYYVNFSFRHDFNPSIFQGRVIKCDTGAIMSDGSVQAGQSGGPMFDQNGCILGVCVSNIKLDDVVYPNINTAIPICDIRNTLQQFARTNDLNVLSNLVASPDVHRVWSLEMPPIRSKL", "length": 509, "header": "tr|Q9W106-1|Q9W106_DROME Isoform 1 of Peroxisomal leader peptide-processing protease OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG3589 PE=3 SV=2 CANONICAL=Q9W106-1" }, "isoforms": [ { "isoform_ac": "Q9W106-1", "url": "https://www.uniprot.org/uniprotkb/Q9W106/entry#Q9W106-1", "sequence": { "sequence": "MLLKIRHALLEVTSPPAAKQSAIIINNELIISSGSILQPHLAVDGDKGAQNKAIVARLQRGQLLDVQNEEQEEDAQIRSLHFVATFDPQQRRPRPIAAPGSRQPHILSRFTAHPLYVFCANEVCRNLHHILLTADSGDAGEVLRSSFVVLGLRKPEKEKSFKRFLAHIANYLRYLQPMHTLDDVLVMCSPFGLENFYKTISIGKVSNVMGRSGCLFAISNALPLGCEGSAVFNNKLRLVGIVICTSFQRHHENVNLTLAANFGYLLRNFMEQLGMSTTAFQLSREPSSFAWERTIVVIESAGQQGTGTFIRVHNKRFILTCAHVVGQNIETVNCRAADREFQSEVIWCNPDSDKPFDLALLTAPQDVPEQCCVRLARSPATVGQMVYNAGFPYYVNFSFRHDFNPSIFQGRVIKCDTGAIMSDGSVQAGQSGGPMFDQNGCILGVCVSNIKLDDVVYPNINTAIPICDIRNTLQQFARTNDLNVLSNLVASPDVHRVWSLEMPPIRSKL", "length": 509, "header": "tr|Q9W106-1|Q9W106_DROME Isoform 1 of Peroxisomal leader peptide-processing protease OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG3589 PE=3 SV=2 CANONICAL=Q9W106-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W106", "url": "https://www.uniprot.org/uniprotkb/Q9W106" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W106", "url": "https://www.uniprot.org/uniprotkb/Q9W106" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W106", "url": "https://www.uniprot.org/uniprotkb/Q9W106" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W106", "url": "https://www.uniprot.org/uniprotkb/Q9W106" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W106", "url": "https://www.uniprot.org/uniprotkb/Q9W106" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W106", "url": "https://www.uniprot.org/uniprotkb/Q9W106" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W106", "url": "https://www.uniprot.org/uniprotkb/Q9W106" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W106", "url": "https://www.uniprot.org/uniprotkb/Q9W106" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W106", "url": "https://www.uniprot.org/uniprotkb/Q9W106" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W106", "url": "https://www.uniprot.org/uniprotkb/Q9W106" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W106", "url": "https://www.uniprot.org/uniprotkb/Q9W106" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG3589", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3589", "resource": "KEGG Pathway" }, { "id": "R-DME-9033241", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9033241", "resource": "Reactome", "description": "Peroxisomal protein import" }, { "id": "R-DME-9033500", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9033500", "resource": "Reactome", "description": "TYSND1 cleaves peroxisomal proteins" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZLD0-1", "protein_name": "Peroxisomal leader peptide-processing protease", "gene_name": "TYSND1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPEDGTAVPWELPGCVVSVSDPSEPDVEPSSCSGAILCRSPGLVLCPAAVLVPFLQPDVTAWPHGDALPPSALRPGLHISVLLAAPPPDAVQQHVACPLALLRCDAFARALPGTLSTAEESTEALPWFCWLRVPGLDTPGGTWTPWAPAATLRKGAALLACGTPFGALCPELFLNALSTGVLSNATGPQRALLLTDARCLPGTQGGPVLALAPTSSPPRLVAVVAATAGCQGGQGLGLALLCSLHALLQSARGVLPELSSLPPPLPLPEAHGSPTLRCAALVESGSSWGSGTLVAPRLLLTCRHVLQLGAPLRVTLRHSTTRDTILQARLVFATAETSPFDVAVLELQDSVPSFQPPDLATTFQPGEAVLALGFGALGRACGPSVTGGVLSAVVGTPPVMLQSTCAVHAGSSGGPLLSAHDGCLLGIVASNARDNTAGTTYPHLNFCIPISLLRTPLARYRCSGNPAAFAPLNAASEGAQAAWRLQQRPPSKL", "length": 493 }, "evidence": [ { "id": "Q9W106", "url": "https://omabrowser.org/oma/group/Q9W106/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0AB32SZ97-1", "protein_name": "Peroxisomal leader peptide-processing protease", "gene_name": "tysnd1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNTAEEACCVVTVSEQLFTPGSENKATSCSGVFLHFQSGIVVCSGIVFSRFINDTLPIKKDTKILYSESFKKKTKVFVDYTHFCANPTDRRKTSRREAHLVMLINCLEFQDAFHKIFKGPENWDFYSGGLDTEVLEDSRFLTWFALLKVPTSPNCPCKETIPWMKSGSLKKGCHVIACGSPFGGLCPDLFMNTISKGIVSNLAGDENALILTDARCLPGTEGGGVFISKGGTSYLVGLIASPLCWKSEEWIGLTLVCSVHLILKNMLQTEGSIKETLTGVSSQLVNGSLQAPLTANRGSGLELYPGVVLVETGWLWGSGVLLNQNLVLTCRHVVDEKSELTVKVNSGGRFHTVRGKVLYSSVVSSPYDIAIVELQEALTDKRTPRFTKHFHTGEDVVVVGYGALGSRCGPSLTSGILSRVITHQSQPVMLQTTCAVQSGASGGAVIRSDTGELLGIVSSNTRDYAAKVTYPHLNFSIPVTLLEPLLRRFAQTGDAAVFNVLDSAVEDVRKWPFPIHPGKYKGKTKCDRPKSNCGLPRRDESAQPHIVSRIASNRVCVFVRVFVCV", "length": 565 }, "evidence": [ { "id": "RGD:1307354", "url": "https://alliancegenome.org/gene/RGD:1307354#orthology", "database": "AGR" }, { "id": "MGI:1919017", "url": "https://alliancegenome.org/gene/MGI:1919017#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-8525", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-8525#orthology", "database": "AGR" }, { "id": "HGNC:28531", "url": "https://alliancegenome.org/gene/HGNC:28531#orthology", "database": "AGR" }, { "id": "FB:FBgn0035065", "url": "https://alliancegenome.org/gene/FB:FBgn0035065#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "B1H261-1", "protein_name": "Peroxisomal leader peptide-processing protease", "gene_name": "Tysnd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRQWGPSLRVAEQAGCVVSASRAGQPDAGSWSCSGVILSRSPGLVLCHGGIFTPFLRTGSAALTQTGAAFLPGDSCSDDLRLHVQWGPTAASPAGRADQELPGLCTPQCASLGLEPGAPSRARARPLQPPRPAQLLLLLSCPAFRSHFARLFGAEAADQWHFVSSAPDDAVSEEEEEDQLRALGWFALLRVQRGAAAEERRGPAVTVAPLGAVAKGAPLLACGSPFGAFCPDIFLNTLSRGVLSNAAGPLLLTDARCLPGTEGGGVFAARPAGALVALVAAPLCWKAREWVGLTLLCAAAPLLQVARSALSRLHPDSTSLSALLPPEVGAPRGLSLRDLGSSWAAAAVLVECGAVWGSGVAVAPRLVVTCRHVAPRETARVLVHSATPRNVAIWGRVVFATQETSPYDIAVVSLEEELNGVPVPVPAEHFHEGEPVSVVGFGVFGQACGPSVTSGILSAVVHVDDAPVMLQTTCAVHGGSSGGPLFSTRSGDLLGIVASNTRDNNTGATYPHLNFSIPITVLQPALKQYSQTGDLCGLRELDHTTEPVRVVWRLQRPLPEAPRSKL", "length": 567 }, "evidence": [ { "id": "RGD:1307354", "url": "https://alliancegenome.org/gene/RGD:1307354#orthology", "database": "AGR" }, { "id": "MGI:1919017", "url": "https://alliancegenome.org/gene/MGI:1919017#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-8525", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-8525#orthology", "database": "AGR" }, { "id": "HGNC:28531", "url": "https://alliancegenome.org/gene/HGNC:28531#orthology", "database": "AGR" }, { "id": "FB:FBgn0035065", "url": "https://alliancegenome.org/gene/FB:FBgn0035065#orthology", "database": "AGR" }, { "id": "Q9W106", "url": "https://omabrowser.org/oma/group/Q9W106/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q2T9J0-1", "protein_name": "Peroxisomal leader peptide-processing protease", "gene_name": "TYSND1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRRQWGSAMRAAEQAGCMVSASRAGQPEAGPWSCSGVILSRSPGLVLCHGGIFVPFLRAGSEVLTAAGAVFLPGDSCRDDLRLHVQWAPTAAGPGGGAERGRPGLCTPQCASLEPGPPAPSRGRPLQPRLPAELLLLLSCPAFWAHFARLFGDEAAEQWRFSSAARDDEVSEDEEADQLRALGWFALLGVRLGQEEVEEERGPAMAVSPLGAVPKGAPLLVCGSPFGAFCPDIFLNTLSCGVLSNVAGPLLLTDARCLPGTEGGGVFTARPAGALVALVVAPLCWKAGEWVGFTLLCAAAPLFRAARDALHRLPHSTAALAALLPPEVGVPWGLPLRDSGPLWAAAAVLVECGTVWGSGVAVAPRLVVTCRHVSPREAARVLVRSTTPKSVAIWGRVVFATQETCPYDIAVVSLEEDLDDVPIPVPAEHFHEGEAVSVVGFGVFGQSCGPSVTSGILSAVVQVNGTPVMLQTTCAVHSGSSGGPLFSNHSGNLLGIITSNTRDNNTGATYPHLNFSIPITVLQPALQQYSQTQDLGGLRELDRAAEPVRVVWRLQRPLAEAPRSKL", "length": 566 }, "evidence": [ { "id": "RGD:1307354", "url": "https://alliancegenome.org/gene/RGD:1307354#orthology", "database": "AGR" }, { "id": "MGI:1919017", "url": "https://alliancegenome.org/gene/MGI:1919017#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-8525", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-8525#orthology", "database": "AGR" }, { "id": "HGNC:28531", "url": "https://alliancegenome.org/gene/HGNC:28531#orthology", "database": "AGR" }, { "id": "FB:FBgn0035065", "url": "https://alliancegenome.org/gene/FB:FBgn0035065#orthology", "database": "AGR" }, { "id": "Q9W106", "url": "https://omabrowser.org/oma/group/Q9W106/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DBA6-1", "protein_name": "Peroxisomal leader peptide-processing protease", "gene_name": "Tysnd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGRQWGPSMRVAEQAGCVVSASRAGQPDAGSWSCSGVILSRNPGLVLCHGGIFTPFLRTGSAALTQTGTAFLPGDSCSDDLRLHVQWGPTAASPAGRADQELPGLCTPQCASLGLEPGAPSRARARPLQPPRPAQLLLLLSCPAFRSHFARLFGADAVDQWHFVSSAPDDAVSEEEEEDQLRALGWFALLRVQRGAAAEERRGPVVTVAPLGAVVKGAPLLACGSPFGAFCPDIFLNTLSRGVLSNAAGPLLLTDARCLPGTEGGGVFAARPAGALVALVAAPLCWKAREWVGLTLLCAAAPLLQVARWALARLHPGSASLSVLLPPPDVSTPRGLPLRDLGPPWAAAAVLVECGTVWGSGVVVAPRLVVTCRHVAPREAARVLVHSATPKNVAIWGQVVFATQETSPYDIAVVSLEEELNGVPTPVPAGHFHEGEPVSVVGFGVFGQACGPSVTSGILSAVVRVDGSPVMLQTTCAVHGGSSGGPLFSSGSGDLLGIVASNTRDNNTGATYPHLNFSIPITVLQPALKQYSQTGDLGGLRELDHTTEPVRVVWRLQRPLSEVPRSKL", "length": 568 }, "evidence": [ { "id": "RGD:1307354", "url": "https://alliancegenome.org/gene/RGD:1307354#orthology", "database": "AGR" }, { "id": "MGI:1919017", "url": "https://alliancegenome.org/gene/MGI:1919017#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-8525", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-8525#orthology", "database": "AGR" }, { "id": "HGNC:28531", "url": "https://alliancegenome.org/gene/HGNC:28531#orthology", "database": "AGR" }, { "id": "FB:FBgn0035065", "url": "https://alliancegenome.org/gene/FB:FBgn0035065#orthology", "database": "AGR" }, { "id": "Q9W106", "url": "https://omabrowser.org/oma/group/Q9W106/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "Q9W106", "url": "https://www.uniprot.org/uniprotkb/Q9W106" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "Q9W106", "url": "https://www.uniprot.org/uniprotkb/Q9W106" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9W106", "url": "https://www.uniprot.org/uniprotkb/Q9W106" } ], "pmid": "" }, { "name": "protein processing", "id": "GO:0016485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016485", "evidence": [ { "database": "UniProtKB", "id": "Q9W106", "url": "https://www.uniprot.org/uniprotkb/Q9W106" } ], "pmid": "" }, { "name": "regulation of fatty acid beta-oxidation", "id": "GO:0031998", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031998", "evidence": [ { "database": "UniProtKB", "id": "Q9W106", "url": "https://www.uniprot.org/uniprotkb/Q9W106" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 255, "end_pos": 257, "annotation": "n_glycosylation_sequon" }, { "start_pos": 396, "end_pos": 398, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-DME-9033235", "name": "Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q7KVJ6-1", "Q7KML2-1", "Q9W3Z3-1", "A0A0B4KHK0-1", "A1Z8D3-1", "Q9VI16-1", "E1JHE4-1", "P17336-1", "P22817-1", "B7Z0E0-1", "Q9W0M0-1", "Q9VIK0-1", "Q9VJ43-1", "Q9W5W8-1", "Q9VB02-1", "Q9VRJ4-1", "Q9W0D7-1", "Q27571-1", "Q9VM58-1", "Q9VM80-1", "Q9W106-1" ], "evidence": [ { "id": "R-DME-9033235", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9033235" } ] }, { "id": "R-DME-9033236", "name": "PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q7KVJ6-1", "Q7KML2-1", "Q9W3Z3-1", "A0A0B4KHK0-1", "A1Z8D3-1", "Q9VI16-1", "E1JHE4-1", "P17336-1", "P22817-1", "B7Z0E0-1", "Q9W0M0-1", "Q9VIK0-1", "Q9VJ43-1", "Q9W5W8-1", "Q9VB02-1", "Q9VRJ4-1", "Q9W0D7-1", "Q27571-1", "Q9VM58-1", "Q9VM80-1", "Q9W106-1" ], "evidence": [ { "id": "R-DME-9033236", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9033236" } ] }, { "id": "R-DME-9033520", "name": "TYSND1 cleaves TYSND1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal matrix", "input_participant_list": [ "R-DME-8933309" ], "output_participant_list": [ "R-DME-9033587", "R-DME-9033589" ], "enzyme_list": [ "Q9W106-1" ], "evidence": [ { "id": "R-DME-9033520", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9033520" } ] } ], "reaction_participants": [ { "participant_id": "R-DME-8933309", "participant_name": "Dmel\\CG3589 [peroxisomal matrix]", "crossref": [ { "id": "Q9W106", "database": "UniProt", "url": "" }, { "id": "FBgn0035065", "database": "FlyBase", "url": "" }, { "id": "Q9W106", "database": "PRO", "url": "" }, { "id": "NP_611968.1", "database": "RefSeq", "url": "" } ] }, { "participant_id": "R-DME-9033587", "participant_name": "Dmel\\CG3589 [peroxisomal matrix]", "crossref": [ { "id": "Q9W106", "database": "UniProt", "url": "" }, { "id": "Q9W106", "database": "PRO", "url": "" }, { "id": "NP_611968.1", "database": "RefSeq", "url": "" }, { "id": "FBgn0035065", "database": "FlyBase", "url": "" } ] }, { "participant_id": "R-DME-9033589", "participant_name": "Dmel\\CG3589 [peroxisomal matrix]", "crossref": [ { "id": "FBgn0035065", "database": "FlyBase", "url": "" }, { "id": "NP_611968.1", "database": "RefSeq", "url": "" }, { "id": "Q9W106", "database": "UniProt", "url": "" }, { "id": "Q9W106", "database": "PRO", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A0B4KHK0", "gene_name": "Gnpat", "activity": [ { "ec_number": "2.3.1.42", "activity": "dihydroxyacetone phosphate + an acyl-CoA = a 1-acylglycerone 3-phosphate + CoA.", "evidence": [ { "id": "A0A0B4KHK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK0" } ] }, { "ec_number": "2.3.1.42", "activity": "", "evidence": [ { "id": "A0A0B4KHK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHK0" } ] } ] }, { "uniprot_ac": "A1Z8D3", "gene_name": "Hao", "activity": [ { "ec_number": "1.1.3.15", "activity": "glycolate + O2 = glyoxylate + H2O2.", "evidence": [ { "id": "A1Z8D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1Z8D3" } ] }, { "ec_number": "1.1.3.15", "activity": "", "evidence": [ { "id": "A1Z8D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1Z8D3" } ] } ] }, { "uniprot_ac": "B7Z0E0", "gene_name": "Idh", "activity": [ { "ec_number": "1.1.1.42", "activity": "D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH.", "evidence": [ { "id": "B7Z0E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B7Z0E0" } ] }, { "ec_number": "1.1.1.42", "activity": "", "evidence": [ { "id": "B7Z0E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B7Z0E0" } ] } ] }, { "uniprot_ac": "E1JHE4", "gene_name": "Fatp1", "activity": [ { "ec_number": "6.2.1.3", "activity": "a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "E1JHE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1JHE4" } ] }, { "ec_number": "6.2.1.3", "activity": "", "evidence": [ { "id": "E1JHE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1JHE4" } ] } ] }, { "uniprot_ac": "P17336", "gene_name": "Cat", "activity": [ { "ec_number": "1.11.1.6", "activity": "2 H2O2 = O2 + 2 H2O.", "evidence": [ { "id": "P17336", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P17336" } ] }, { "ec_number": "1.11.1.6", "activity": "", "evidence": [ { "id": "P17336", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P17336" } ] } ] }, { "uniprot_ac": "P22817", "gene_name": "Ide", "activity": [ { "ec_number": "3.4.24.56", "activity": "Degradation of insulin, glucagon and other polypeptides. No action on proteins.", "evidence": [ { "id": "P22817", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P22817" } ] }, { "ec_number": "3.4.24.56", "activity": "", "evidence": [ { "id": "P22817", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P22817" } ] } ] }, { "uniprot_ac": "Q27571", "gene_name": "Nos", "activity": [ { "ec_number": "1.14.13.39", "activity": "2 L-arginine + 3 NADPH + 4 O2 + H(+) = 2 L-citrulline + 2 nitric oxide + 3 NADP(+) + 4 H2O.", "evidence": [ { "id": "Q27571", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q27571" } ] }, { "ec_number": "1.14.13.39", "activity": "", "evidence": [ { "id": "Q27571", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q27571" } ] } ] }, { "uniprot_ac": "Q7KML2", "gene_name": "Acox1", "activity": [ { "ec_number": "1.3.3.6", "activity": "a 2,3-saturated acyl-CoA + O2 = a (2E)-enoyl-CoA + H2O2.", "evidence": [ { "id": "Q7KML2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7KML2" } ] }, { "ec_number": "1.3.3.6", "activity": "", "evidence": [ { "id": "Q7KML2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7KML2" } ] } ] }, { "uniprot_ac": "Q7KVJ6", "gene_name": "Fatp2", "activity": [ { "ec_number": "6.2.1.3", "activity": "a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "Q7KVJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7KVJ6" } ] }, { "ec_number": "6.2.1.3", "activity": "", "evidence": [ { "id": "Q7KVJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7KVJ6" } ] } ] }, { "uniprot_ac": "Q9VB02", "gene_name": "CROT", "activity": [ { "ec_number": "2.3.-.-", "activity": "", "evidence": [ { "id": "Q9VB02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VB02" } ] }, { "ec_number": "2.3.1.137", "activity": "octanoyl-CoA + (R)-carnitine = O-octanoyl-(R)-carnitine + CoA.", "evidence": [ { "id": "Q9VB02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VB02" } ] } ] }, { "uniprot_ac": "Q9VI16", "gene_name": "CRAT", "activity": [ { "ec_number": "2.3.-.-", "activity": "", "evidence": [ { "id": "Q9VI16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VI16" } ] }, { "ec_number": "2.3.1.7", "activity": "(R)-carnitine + acetyl-CoA = O-acetyl-(R)-carnitine + CoA.", "evidence": [ { "id": "Q9VI16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VI16" } ] } ] }, { "uniprot_ac": "Q9VIK0", "gene_name": "Amacr", "activity": [ { "ec_number": "5.1.99.4", "activity": "a (2S)-2-methylacyl-CoA = a (2R)-2-methylacyl-CoA.", "evidence": [ { "id": "Q9VIK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VIK0" } ] } ] }, { "uniprot_ac": "Q9VJ43", "gene_name": "ScpX", "activity": [ { "ec_number": "2.3.1.176", "activity": "4,8,12-trimethyltridecanoyl-CoA + propanoyl-CoA = 3-oxopristanoyl-CoA + CoA.", "evidence": [ { "id": "Q9VJ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJ43" } ] }, { "ec_number": "2.3.1.16", "activity": "an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA.", "evidence": [ { "id": "Q9VJ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJ43" } ] }, { "ec_number": "2.3.1.155", "activity": "tetradecanoyl-CoA + acetyl-CoA = 3-oxohexadecanoyl-CoA + CoA.", "evidence": [ { "id": "Q9VJ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJ43" } ] }, { "ec_number": "2.3.1.176", "activity": "", "evidence": [ { "id": "Q9VJ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJ43" } ] }, { "ec_number": "2.3.1.16", "activity": "", "evidence": [ { "id": "Q9VJ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJ43" } ] }, { "ec_number": "2.3.1.155", "activity": "", "evidence": [ { "id": "Q9VJ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJ43" } ] } ] }, { "uniprot_ac": "Q9VM58", "gene_name": "Hmgcl", "activity": [ { "ec_number": "4.1.3.4", "activity": "(3S)-3-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA.", "evidence": [ { "id": "Q9VM58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VM58" } ] }, { "ec_number": "4.1.3.4", "activity": "", "evidence": [ { "id": "Q9VM58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VM58" } ] } ] }, { "uniprot_ac": "Q9VM80", "gene_name": "Daao2", "activity": [ { "ec_number": "1.4.3.3", "activity": "D-lysine + O2 + H2O = 6-amino-2-oxohexanoate + H2O2 + NH4(+).", "evidence": [ { "id": "Q9VM80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VM80" } ] }, { "ec_number": "1.-.-.-", "activity": "", "evidence": [ { "id": "Q9VM80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VM80" } ] } ] }, { "uniprot_ac": "Q9VRJ4", "gene_name": "Dhrs4", "activity": [ { "ec_number": "1.-.-.-", "activity": "", "evidence": [ { "id": "Q9VRJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VRJ4" } ] }, { "ec_number": "1.1.1.184", "activity": "a secondary alcohol + NADP(+) = a ketone + NADPH + H(+).", "evidence": [ { "id": "Q9VRJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VRJ4" } ] } ] }, { "uniprot_ac": "Q9W0D7", "gene_name": "Pex10", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q9W0D7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W0D7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q9W0D7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W0D7" } ] } ] }, { "uniprot_ac": "Q9W0M0", "gene_name": "Dci", "activity": [ { "ec_number": "5.3.3.8", "activity": "a (3Z)-enoyl-CoA = a 4-saturated (2E)-enoyl-CoA.", "evidence": [ { "id": "Q9W0M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W0M0" } ] } ] }, { "uniprot_ac": "Q9W106", "gene_name": "Dmel\\CG3589", "activity": [ { "ec_number": "3.4.21.-", "activity": "", "evidence": [ { "id": "Q9W106", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W106" } ] } ] }, { "uniprot_ac": "Q9W3Z3", "gene_name": "Agxt", "activity": [ { "ec_number": "2.6.1.44", "activity": "2-oxobutanoate + L-alanine = (2S)-2-aminobutanoate + pyruvate.", "evidence": [ { "id": "Q9W3Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3Z3" } ] }, { "ec_number": "2.6.1.44", "activity": "", "evidence": [ { "id": "Q9W3Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3Z3" } ] } ] }, { "uniprot_ac": "Q9W5W8", "gene_name": "Dmel\\CG9577", "activity": [ { "ec_number": "5.3.3.21", "activity": "a (3E,5Z)-dienoyl-CoA = a (2E,4E)-(5,6-saturated)-dienoyl-CoA.", "evidence": [ { "id": "Q9W5W8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W5W8" } ] }, { "ec_number": "5.3.3.21", "activity": "", "evidence": [ { "id": "Q9W5W8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W5W8" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 255, "end_pos": 257 }, { "start_pos": 396, "end_pos": 398 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"yes" } }, { "uniprot_canonical_ac": "Q9W115-1", "uniprot_ac": "Q9W115", "uniprot_id": "Q9W115_DROME", "mass": { "chemical_mass": 45252.0, "monoisotopic_mass": 45252.0 }, "refseq": { "ac": "NP_611962", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611962" }, "gene_names": [ { "name": "Dmel\\CG3880", "type": "recommended", "evidence": [ { "id": "Q9W115", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W115" } ] }, { "name": "CG3880", "type": "synonym", "evidence": [ { "id": "NP_611962", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611962" }, { "id": "Q9W115", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W115" } ] }, { "name": "Dmel\\CG3880", "type": "synonym", "evidence": [ { "id": "NP_611962", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611962" } ] }, { "name": "Dmel_CG3880", "type": "synonym", "evidence": [ { "id": "Q9W115", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W115" } ] } ], "protein_names": [ { "name": "Suppressor APC domain-containing protein", "type": "recommended", "evidence": [ { "id": "Q9W115", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W115/entry#names_and_taxonomy" } ] }, { "name": "CG3880-PA", "type": "synonym", "evidence": [ { "id": "NP_611962", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611962" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_611962", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611962" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W115", "url": "https://www.uniprot.org/uniprotkb/Q9W115" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG3880", "url": "https://www.uniprot.org/uniprotkb/Q9W115", "locus": { "chromosome": "2R", "start_pos": 24762605, "end_pos": 24760664, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0035057", "url": "https://www.ensemblgenomes.org/id/FBgn0035057" } ] } } ], "crossref": [ { "id": "FB:FBgn0035057", "url": "https://alliancegenome.org/gene/FB:FBgn0035057", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0035057", "url": "https://bgee.org/?page=gene&gene_id=FBgn0035057", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0035057", "url": "https://flybase.org/reports/FBgn0035057", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "37957", "url": "https://www.ncbi.nlm.nih.gov/gene/37957", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057953", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057953", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG3880", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3880", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WQLNLMA", "url": "https://omabrowser.org/oma/group/WQLNLMA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W115", "url": "https://www.orthodb.org/?gene=Q9W115", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14907", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14907", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14907:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14907:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11414", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11414", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25825", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25825", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_611962", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611962", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W115", "url": "https://www.uniprot.org/uniprotkb/Q9W115", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W115-1", "url": "https://www.uniprot.org/uniprotkb/Q9W115-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRQNKNTSTSLLNLSIGDVGGSHPQGQSQFWELDTLPKQFVLSMKKLFDILDDKQTGYVRFTDIEKGWQDDGSKGLPRGVVDSLRRVTPSSGLLSFERFCAGLKLCLLRNQQNAVEDLKLRPRSHGTLAPEMEFHSPAPPPKPPRQVPKSPALGKDDIRHALQNWQLNLMADAGKSKTTQSREQFEHRGSADGGSSSTSASATDWSLALPAVPKKTSSKRRESRRHTLQHGIDYNMLKRLKQLEEQRELLLFGLDGVEKARDWYMMQVLNVQEQIKYFGRLGTRFDQWSELQQERLNFQRARVFEANRSLQILADTWEHGGYPLHINLAVPTPTVPKPRQMSDLLSRVREKPPLLSDLYEAQHSHSHPQFLRAMPNFVLSQPSPVSQSSAGLGDADVVY", "length": 400, "header": "tr|Q9W115-1|Q9W115_DROME Isoform 1 of Suppressor APC domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG3880 PE=4 SV=1 CANONICAL=Q9W115-1" }, "isoforms": [ { "isoform_ac": "Q9W115-1", "url": "https://www.uniprot.org/uniprotkb/Q9W115/entry#Q9W115-1", "sequence": { "sequence": "MLRQNKNTSTSLLNLSIGDVGGSHPQGQSQFWELDTLPKQFVLSMKKLFDILDDKQTGYVRFTDIEKGWQDDGSKGLPRGVVDSLRRVTPSSGLLSFERFCAGLKLCLLRNQQNAVEDLKLRPRSHGTLAPEMEFHSPAPPPKPPRQVPKSPALGKDDIRHALQNWQLNLMADAGKSKTTQSREQFEHRGSADGGSSSTSASATDWSLALPAVPKKTSSKRRESRRHTLQHGIDYNMLKRLKQLEEQRELLLFGLDGVEKARDWYMMQVLNVQEQIKYFGRLGTRFDQWSELQQERLNFQRARVFEANRSLQILADTWEHGGYPLHINLAVPTPTVPKPRQMSDLLSRVREKPPLLSDLYEAQHSHSHPQFLRAMPNFVLSQPSPVSQSSAGLGDADVVY", "length": 400, "header": "tr|Q9W115-1|Q9W115_DROME Isoform 1 of Suppressor APC domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG3880 PE=4 SV=1 CANONICAL=Q9W115-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 335, "start_aa": "Thr", "end_pos": 335, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr335", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 89, "start_aa": "Thr", "end_pos": 89, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr89", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W115", "url": "https://www.uniprot.org/uniprotkb/Q9W115" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W115", "url": "https://www.uniprot.org/uniprotkb/Q9W115" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W115", "url": "https://www.uniprot.org/uniprotkb/Q9W115" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W115", "url": "https://www.uniprot.org/uniprotkb/Q9W115" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W115", "url": "https://www.uniprot.org/uniprotkb/Q9W115" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": 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Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W115", "url": "https://www.uniprot.org/uniprotkb/Q9W115" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W115", "url": "https://www.uniprot.org/uniprotkb/Q9W115" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi 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"https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045305", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045305", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG4612", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG4612", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QPAAIMF", "url": "https://omabrowser.org/oma/group/QPAAIMF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W158", "url": "https://www.orthodb.org/?gene=Q9W158", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24012", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24012", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-156827", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-156827", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-429947", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-429947", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-450408", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-450408", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-72649", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-72649", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-975956", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-975956", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-975957", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-975957", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001246493", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001246493", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W158", "url": "https://www.uniprot.org/uniprotkb/Q9W158", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W158-1", "url": "https://www.uniprot.org/uniprotkb/Q9W158-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFVNSMTFRGNPANYHQQQPALNHHTLAAAHHQQQLHHHAAAAGHLSHVGGGHAASNHLAAAAVLGRHGHNSLGSGHTSTSSHSANVGVGVGGGALASGSTGGSGGNSSPDSGKIYIKNLERSIDNKAVYDTFSVFGNILNCNVAKDEDGNSRGYGFVHFDSEEAARAAIEKVNGMLCNNQKVHVVKFIPRRDREQEKATHFKNLYVKNLSEEFTEQHLREMFEPYGRITSHKLMLDEEGRSRRFGFVAYENPQSALAAVIGLHGKQLGDNKFLYVARALSKAERQQEINRKLEERKRQKAGQIFYY", "length": 307, "header": "tr|Q9W158-1|Q9W158_DROME Isoform 1 of RRM domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG4612 PE=1 SV=1 CANONICAL=Q9W158-1" }, "isoforms": [ { "isoform_ac": "Q9W158-1", "url": "https://www.uniprot.org/uniprotkb/Q9W158/entry#Q9W158-1", "sequence": { "sequence": "MFVNSMTFRGNPANYHQQQPALNHHTLAAAHHQQQLHHHAAAAGHLSHVGGGHAASNHLAAAAVLGRHGHNSLGSGHTSTSSHSANVGVGVGGGALASGSTGGSGGNSSPDSGKIYIKNLERSIDNKAVYDTFSVFGNILNCNVAKDEDGNSRGYGFVHFDSEEAARAAIEKVNGMLCNNQKVHVVKFIPRRDREQEKATHFKNLYVKNLSEEFTEQHLREMFEPYGRITSHKLMLDEEGRSRRFGFVAYENPQSALAAVIGLHGKQLGDNKFLYVARALSKAERQQEINRKLEERKRQKAGQIFYY", "length": 307, "header": "tr|Q9W158-1|Q9W158_DROME Isoform 1 of RRM domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG4612 PE=1 SV=1 CANONICAL=Q9W158-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 7, "start_aa": "Thr", "end_pos": 7, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr7", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "Q9W158", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9W158" } ], "filter_code": "00000000000000001000.0000000.00000001000000.1000000.0100000000.110100100001111011.10000.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_reported_with_glycan" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W158", "url": "https://www.uniprot.org/uniprotkb/Q9W158" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W158", "url": "https://www.uniprot.org/uniprotkb/Q9W158" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W158", "url": "https://www.uniprot.org/uniprotkb/Q9W158" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W158", "url": "https://www.uniprot.org/uniprotkb/Q9W158" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W158", "url": "https://www.uniprot.org/uniprotkb/Q9W158" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W158", "url": "https://www.uniprot.org/uniprotkb/Q9W158" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W158", "url": "https://www.uniprot.org/uniprotkb/Q9W158" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W158", "url": "https://www.uniprot.org/uniprotkb/Q9W158" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W158", "url": "https://www.uniprot.org/uniprotkb/Q9W158" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W158", "url": "https://www.uniprot.org/uniprotkb/Q9W158" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W158", "url": "https://www.uniprot.org/uniprotkb/Q9W158" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] }, { "title": "Quantitative and site-specific chemoproteomic profiling of O-GlcNAcylation in Drosophila.", "journal": "Bioorganic & medicinal chemistry", "date": "2025-04-10", "authors": "Lei Cong, Chen Zihan, Hao Yi, Huang Wanping, Chu Tianyu, Xiao Kangming, Zhang Che, Zhou Wen, Li Chenjian, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9W158", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9W158" } ], "reference": [ { "type": "PubMed", "id": "40245499", "url": "https://glygen.org/publication/PubMed/40245499" } ] } ], "pathway": [ { "id": "dme:Dmel_CG4612", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG4612", "resource": "KEGG Pathway" }, { "id": "R-DME-156827", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-156827", "resource": "Reactome", "description": "L13a-mediated translational silencing of Ceruloplasmin expression" }, { "id": "R-DME-429947", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-429947", "resource": "Reactome", "description": "Deadenylation of mRNA" }, { "id": "R-DME-450408", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-450408", "resource": "Reactome", "description": "AUF1 (hnRNP D0) binds and destabilizes mRNA" }, { "id": "R-DME-72649", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-72649", "resource": "Reactome", "description": "Translation initiation complex formation" }, { "id": "R-DME-975956", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-975956", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" }, { "id": "R-DME-975957", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-975957", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZSJ2-1", "protein_name": "Poly(A) binding protein, cytoplasmic 1-like 2A", "gene_name": "Pabpc1l2b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "QPSIRPKTGNPNPQVQHAARSLSSSCPERGRPRGCALVPQPRLSPPPRCPLAAPQPRSPAAATGGTKETEAFPAARTTDANTPRPQPHAALPPAPRTPASPRPSAAAGCGLRAAETDSALRAPGRRSPPGLTRSLPAARPERGPGPQPPREPPAGVPAPTGPRRLSAPSVPGKGGRGSGPAAAVTVASAATVAAEVAAAEAAAAAAAEAAAATVAEAVAEASVAEAEAEVEAEVEAEAAAEASLGEAAAAAALAREKAEAGGAAAAVAATEASLAEASLEEASLAEAAASPSYGRVDMDEELAAALAAEEEEAAAGGSDDGNPDFPTASLYVGDLHPEVTESMLYEKFSPAGPILSIRLCRDKVTRRSLGYAYVNYQQPVDAKRALETMNFDVINGRPVRIMWSQRDPSLRKSGVGNVFIKNLGKTIDNKALYNIFSAFGNILSCKVACDEKGPKGYGFVHFQKQESAERAIDALNGMFLNYRKIFVGRFKSHKEREAERGAWARQSTSADFKDFDDDSDDEATFR", "length": 526 }, "evidence": [ { "id": "HGNC:31852", "url": "https://alliancegenome.org/gene/HGNC:31852#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LJK2-1", "protein_name": "Poly(A) binding protein, cytoplasmic 1-like 2A", "gene_name": "Pabpc1l2a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDEELAAALAAEEEEAAAGGSDDGNPDFPTASLYVGDLHPEVTESMLYEKFSPAGPILSIRLCRDKVTRRSLGYAYVNYQQPVDAKRALETMNFDVINGRPVRIMWSQRDPSLRKSGVGNVFIKNLGKTIDNKALYNIFSAFGNILSCKVACDEKGPKGYGFVHFQKQESAERAIDALNGMFLNYRKIFVGRFKSHKEREAERGAWARQSTSADFKDFDDDSDDEATFR", "length": 229 }, "evidence": [ { "id": "HGNC:27989", "url": "https://alliancegenome.org/gene/HGNC:27989#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QB54-1", "protein_name": "Polyadenylate-binding protein 1A", "gene_name": "pabpc1a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMMTRRSLGYAYVNFQQPADAERALDTMNFDVIKGRPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYGFVHFETHEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAEMGARAKEFTNVYIKNFGEDMDDEKLKEIFCKYGPALSIRVMTDDSGKSKGFGFVSFERHEDAQRAVDEMNGKEMNGKQVYVGRAQKKGERQTELKRKFEQMKQDRMTRYQGVNLYVKNLDDGLDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAHLTSQYMQRMASVRAVPNPVLNPYQPAPPSGYFMAAIPQAQNRAAYYPTSQLAQLRPSPRWATQGVRPQHFQNMPNAAVRPSAPRPQTFNPVRPASQVPRMMTSQRMGSQAMGPRPAAAGAATGPAQVRGVPQYKYAPGVRNPQQHMPTQPQVPMQQPAVHVQGQEPLTASMLAAAPPQEQKQMLGERLFPLIQNMHPSLAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHQAKEAAQKSVPSPAVPAV", "length": 634 }, "evidence": [ { "id": "HGNC:31852", "url": "https://alliancegenome.org/gene/HGNC:31852#orthology", "database": "AGR" }, { "id": "HGNC:27989", "url": "https://alliancegenome.org/gene/HGNC:27989#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5JQF8-1", "protein_name": "Polyadenylate-binding protein 1-like 2", "gene_name": "PABPC1L2B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALETLNFDVIKGRPVRIMWSQRDPSLRKSGVGNVFIKNLGKTIDNKALYNIFSAFGNILSCKVACDEKGPKGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGRFKSHKEREAERGAWARQSTSADVKDFEEDTDEEATLR", "length": 200 }, "evidence": [ { "id": "HGNC:31852", "url": "https://alliancegenome.org/gene/HGNC:31852#orthology", "database": "AGR" }, { "id": "HGNC:27989", "url": "https://alliancegenome.org/gene/HGNC:27989#orthology", "database": "AGR" }, { "id": "FB:FBgn0035016", "url": "https://alliancegenome.org/gene/FB:FBgn0035016#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "Q9W158", "url": "https://www.uniprot.org/uniprotkb/Q9W158" } ], "pmid": "" }, { "name": "mRNA 3'-UTR binding", "id": "GO:0003730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", "evidence": [ { "database": "UniProtKB", "id": "Q9W158", "url": "https://www.uniprot.org/uniprotkb/Q9W158" } ], "pmid": "" }, { "name": "poly(A) binding", "id": "GO:0008143", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008143", "evidence": [ { "database": "UniProtKB", "id": "Q9W158", "url": "https://www.uniprot.org/uniprotkb/Q9W158" } ], "pmid": "" }, { "name": "poly(U) RNA binding", "id": "GO:0008266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008266", "evidence": [ { "database": "UniProtKB", "id": "Q9W158", "url": "https://www.uniprot.org/uniprotkb/Q9W158" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9W158", "url": "https://www.uniprot.org/uniprotkb/Q9W158" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9W158", "url": "https://www.uniprot.org/uniprotkb/Q9W158" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "Q9W158", "url": "https://www.uniprot.org/uniprotkb/Q9W158" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "Q9W158", "url": "https://www.uniprot.org/uniprotkb/Q9W158" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of translation", "id": "GO:0045727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045727", "evidence": [ { "database": "UniProtKB", "id": "Q9W158", "url": "https://www.uniprot.org/uniprotkb/Q9W158" } ], "pmid": "" }, { "name": "long-term memory", "id": "GO:0007616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007616", "evidence": [ { "database": "UniProtKB", "id": "Q9W158", "url": "https://www.uniprot.org/uniprotkb/Q9W158" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 107, "end_pos": 109, "annotation": "n_glycosylation_sequon" }, { "start_pos": 209, "end_pos": 211, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9W158", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W158" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 113, "end_pos": 185, "start_aa": "Gly", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 7 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 107, "end_pos": 109 }, { "start_pos": 209, "end_pos": 211 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "exact_o_linked_glycan_sites", "count": 1 }, { "field": "exact_o_linked_glycans", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "exact_o_linked_glycan_sites", "count": 1 }, { "field": "exact_o_linked_glycans", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 12 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9W170-1", "uniprot_ac": "Q9W170", "uniprot_id": "Q9W170_DROME", "mass": { "chemical_mass": 46373.0, "monoisotopic_mass": 46373.0 }, "refseq": { "ac": "NP_611914", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611914" }, "gene_names": [ { "name": "anon-WO0140519.253", "type": "recommended", "evidence": [ { "id": "Q9W170", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W170" } ] }, { "name": "CG3492", "type": "synonym", "evidence": [ { "id": "NP_611914", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611914" }, { "id": "Q9W170", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W170" } ] }, { "name": "Dmel\\CG3492", "type": "synonym", "evidence": [ { "id": "NP_611914", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611914" }, { "id": "Q9W170", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W170" } ] }, { "name": "Dmel_CG3492", "type": "synonym", "evidence": [ { "id": "Q9W170", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W170" } ] }, { "name": "anon-WO0140519.253", "type": "synonym", "evidence": [ { "id": "NP_611914", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611914" } ] } ], "protein_names": [ { "name": "PPIase cyclophilin-type domain-containing protein", "type": "recommended", "evidence": [ { "id": "Q9W170", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W170/entry#names_and_taxonomy" } ] }, { "name": "CG3492-PA", "type": "synonym", "evidence": [ { "id": "NP_611914", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611914" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_611914", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611914" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W170", "url": "https://www.uniprot.org/uniprotkb/Q9W170" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "anon-WO0140519.253", "url": "https://www.uniprot.org/uniprotkb/Q9W170", "locus": { "chromosome": "2R", "start_pos": 24474226, "end_pos": 24472712, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0035007", "url": "https://www.ensemblgenomes.org/id/FBgn0035007" } ] } } ], "crossref": [ { "id": "FB:FBgn0035007", "url": "https://alliancegenome.org/gene/FB:FBgn0035007", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0035007", "url": "https://bgee.org/?page=gene&gene_id=FBgn0035007", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0035007", "url": "https://flybase.org/reports/FBgn0035007", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "37902", "url": "https://www.ncbi.nlm.nih.gov/gene/37902", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002130", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002130", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG3492", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3492", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MSNIEHD", "url": "https://omabrowser.org/oma/group/MSNIEHD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W170", "url": "https://www.orthodb.org/?gene=Q9W170", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF00160", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00160", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_611914", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611914", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W170", "url": "https://www.uniprot.org/uniprotkb/Q9W170", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W170-1", "url": "https://www.uniprot.org/uniprotkb/Q9W170-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFIRGDAPQASRGKIPQIPSSMTPYVAAVKRGPYTMTNPVYNTHNPNLVGLDGQVEDSRPKHTFNVKRQELENNYRHHQRLIPVPTSRRTMPKIRSHIVMNEQRELYRQHRDRMSNIKGKVNTYLPPPKVQIEGNGMELSYMEMLTALYKKSNNTLRTFTKSPERLAAGRWRNANLAREKERRQLEKNKEFHKGGELFDPEAGKSKRYKPKSSGSFSCEIPMHVLHRYENLMDQCDVGVLCKLLRPQIYLDIEVREARIQGRLIIQLFTEACPQVVLEFMRICTQNNSSAIVFNRALAPIWMEGRLAMDPQRSTELTNIEHDFEVLNHGVDAGILSFPSRYVRGNARTAVNFTISFKPLSILNGRRIAFGKVRKGMQLLERIQVAVGHLPMSHNLISLTDCGVI", "length": 404, "header": "tr|Q9W170-1|Q9W170_DROME Isoform 1 of PPIase cyclophilin-type domain-containing protein OS=Drosophila melanogaster OX=7227 GN=anon-WO0140519.253 PE=4 SV=1 CANONICAL=Q9W170-1" }, "isoforms": [ { "isoform_ac": "Q9W170-1", "url": "https://www.uniprot.org/uniprotkb/Q9W170/entry#Q9W170-1", "sequence": { "sequence": "MFIRGDAPQASRGKIPQIPSSMTPYVAAVKRGPYTMTNPVYNTHNPNLVGLDGQVEDSRPKHTFNVKRQELENNYRHHQRLIPVPTSRRTMPKIRSHIVMNEQRELYRQHRDRMSNIKGKVNTYLPPPKVQIEGNGMELSYMEMLTALYKKSNNTLRTFTKSPERLAAGRWRNANLAREKERRQLEKNKEFHKGGELFDPEAGKSKRYKPKSSGSFSCEIPMHVLHRYENLMDQCDVGVLCKLLRPQIYLDIEVREARIQGRLIIQLFTEACPQVVLEFMRICTQNNSSAIVFNRALAPIWMEGRLAMDPQRSTELTNIEHDFEVLNHGVDAGILSFPSRYVRGNARTAVNFTISFKPLSILNGRRIAFGKVRKGMQLLERIQVAVGHLPMSHNLISLTDCGVI", "length": 404, "header": "tr|Q9W170-1|Q9W170_DROME Isoform 1 of PPIase cyclophilin-type domain-containing protein OS=Drosophila melanogaster OX=7227 GN=anon-WO0140519.253 PE=4 SV=1 CANONICAL=Q9W170-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 155, "start_aa": "Thr", "end_pos": 155, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr155", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "Q9W170", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9W170" } ], "filter_code": "00000000000000001000.0000000.00000001000000.1000000.0100000000.110100100001111011.10000.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_reported_with_glycan" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W170", "url": "https://www.uniprot.org/uniprotkb/Q9W170" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W170", "url": "https://www.uniprot.org/uniprotkb/Q9W170" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W170", "url": "https://www.uniprot.org/uniprotkb/Q9W170" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W170", "url": "https://www.uniprot.org/uniprotkb/Q9W170" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W170", "url": "https://www.uniprot.org/uniprotkb/Q9W170" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W170", "url": "https://www.uniprot.org/uniprotkb/Q9W170" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W170", "url": "https://www.uniprot.org/uniprotkb/Q9W170" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W170", "url": "https://www.uniprot.org/uniprotkb/Q9W170" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W170", "url": "https://www.uniprot.org/uniprotkb/Q9W170" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"https://www.oglcnac.mcw.edu/search/?query_protein=Q9W194" } ], "filter_code": "00000000000000001000.0000000.00000001000000.1000000.0100000000.110100100001111011.10000.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_reported_with_glycan", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W194", "url": "https://www.uniprot.org/uniprotkb/Q9W194" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W194", "url": "https://www.uniprot.org/uniprotkb/Q9W194" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W194", "url": "https://www.uniprot.org/uniprotkb/Q9W194" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W194", "url": "https://www.uniprot.org/uniprotkb/Q9W194" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W194", "url": "https://www.uniprot.org/uniprotkb/Q9W194" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W194", "url": "https://www.uniprot.org/uniprotkb/Q9W194" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W194", "url": "https://www.uniprot.org/uniprotkb/Q9W194" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi 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"categories": [ "Protein Classification" ] }, { "id": "FBgn0034989", "url": "https://flybase.org/reports/FBgn0034989", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "37876", "url": "https://www.ncbi.nlm.nih.gov/gene/37876", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG3356", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3356", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EKHYYFI", "url": "https://omabrowser.org/oma/group/EKHYYFI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W196", "url": "https://www.orthodb.org/?gene=Q9W196", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45700", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45700", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45700:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45700:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00632", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00632", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_611896", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611896", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W196", "url": "https://www.uniprot.org/uniprotkb/Q9W196", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W196-1", "url": "https://www.uniprot.org/uniprotkb/Q9W196-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFGFDGEYRRRPVQSLGGASHTCDRDTVIRKAALERQKRNELRQKENGAVVLQSYARSFIHRQRRKRAEREVFDIYLMGHKDGIVEDESLTFLLRRLNFFYSIREAKDSERLIEVCQQILRQPARLLQHSSPDSLWLLRLCKLLDTCLLQLSLSHTAQAIPLRMLETFTTVSSVQQYMKDEAVLFQYMERVFGFLIARNYFVRLRRLLDDKCPPLDGETLHAPSPLAEALLQLLLRPLEVAKRASAGGQMSSMSMAVCRNFTRDILATPHTDPLRYFVLPCFALNVDFPFDLLMRSLYDALESAGPAESDSTSSRRSFLFYGVETGHKTTRMDSIFSSFLLNSLMVLDRRQLATLHQSPLLVIYVRLIAEMMPNILQLPKSTLRGHANAPHRHRDGDDDSEESEDEDEELPAARTLDYDMEQTCRTSGELSVKERECLLESIAILNETERVDFIVQQLDPHIENTHLIYALCEICHNLMIYNKHAVFEYKLLYTLAFTPKFIRAVWFKLAAESTQLGFSAPLTLISKGVVPKHQGVDRTIPLLATFCMLFGRLLPTLHDVEFVENKLLLQVHSTINHVRLMPFSIAEIIQMSKTLKDISMGLVELAFPETRSNLANYRKVLGHTEADDKKLRHQKQIWANLLNVVVFVLNQIHTRDLRLGFCPEDHWTVTRLDLPLDRPTDLPLTHSSRLRGIRPFQPIRDFTREDFENGPPMSTKQIRSITILREIPFVVPFNKRVSILQSLVAASKMRVQGNMQAFLQGPSVLITVRRSHLYEDAYDKLRPDNEPDLRFKFRIQFVSSLGLDEAGIDGGGVFREFLSELIKTAFDPNRGFFMVTTDNKLYPNPNVADLFEDYEKHYYFIGRILGKSIYENLLVELPLAEFFLTKLAGKYSDVDIHQLASLDPELYRNLLYLKDYSGDVSELNLDFTVASSSLGQTQIVELKPQGQSIPVTNSNRIEYLQLIADYKLNVQIRRHCNAFRKGLSNVLPIEWLYMFSNKELQILISGAEIPIDLEDLKKHCEYGGEFSPEHPSIVTFWEVLEGFDDMQRRQLLKFVTSCSRPPLLGFKDLDPPFFIQNTGDMERLPTASTCTNLLKLPPFKTVEQMREKLLYAIQSGAGFELS", "length": 1122, "header": "tr|Q9W196-1|Q9W196_DROME Isoform 1 of Ubiquitin-protein ligase E3C OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG3356 PE=1 SV=1 CANONICAL=Q9W196-1" }, "isoforms": [ { "isoform_ac": "Q9W196-1", "url": "https://www.uniprot.org/uniprotkb/Q9W196/entry#Q9W196-1", "sequence": { "sequence": "MFGFDGEYRRRPVQSLGGASHTCDRDTVIRKAALERQKRNELRQKENGAVVLQSYARSFIHRQRRKRAEREVFDIYLMGHKDGIVEDESLTFLLRRLNFFYSIREAKDSERLIEVCQQILRQPARLLQHSSPDSLWLLRLCKLLDTCLLQLSLSHTAQAIPLRMLETFTTVSSVQQYMKDEAVLFQYMERVFGFLIARNYFVRLRRLLDDKCPPLDGETLHAPSPLAEALLQLLLRPLEVAKRASAGGQMSSMSMAVCRNFTRDILATPHTDPLRYFVLPCFALNVDFPFDLLMRSLYDALESAGPAESDSTSSRRSFLFYGVETGHKTTRMDSIFSSFLLNSLMVLDRRQLATLHQSPLLVIYVRLIAEMMPNILQLPKSTLRGHANAPHRHRDGDDDSEESEDEDEELPAARTLDYDMEQTCRTSGELSVKERECLLESIAILNETERVDFIVQQLDPHIENTHLIYALCEICHNLMIYNKHAVFEYKLLYTLAFTPKFIRAVWFKLAAESTQLGFSAPLTLISKGVVPKHQGVDRTIPLLATFCMLFGRLLPTLHDVEFVENKLLLQVHSTINHVRLMPFSIAEIIQMSKTLKDISMGLVELAFPETRSNLANYRKVLGHTEADDKKLRHQKQIWANLLNVVVFVLNQIHTRDLRLGFCPEDHWTVTRLDLPLDRPTDLPLTHSSRLRGIRPFQPIRDFTREDFENGPPMSTKQIRSITILREIPFVVPFNKRVSILQSLVAASKMRVQGNMQAFLQGPSVLITVRRSHLYEDAYDKLRPDNEPDLRFKFRIQFVSSLGLDEAGIDGGGVFREFLSELIKTAFDPNRGFFMVTTDNKLYPNPNVADLFEDYEKHYYFIGRILGKSIYENLLVELPLAEFFLTKLAGKYSDVDIHQLASLDPELYRNLLYLKDYSGDVSELNLDFTVASSSLGQTQIVELKPQGQSIPVTNSNRIEYLQLIADYKLNVQIRRHCNAFRKGLSNVLPIEWLYMFSNKELQILISGAEIPIDLEDLKKHCEYGGEFSPEHPSIVTFWEVLEGFDDMQRRQLLKFVTSCSRPPLLGFKDLDPPFFIQNTGDMERLPTASTCTNLLKLPPFKTVEQMREKLLYAIQSGAGFELS", "length": 1122, "header": "tr|Q9W196-1|Q9W196_DROME Isoform 1 of Ubiquitin-protein ligase E3C OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG3356 PE=1 SV=1 CANONICAL=Q9W196-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W196", "url": "https://www.uniprot.org/uniprotkb/Q9W196" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W196", "url": "https://www.uniprot.org/uniprotkb/Q9W196" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W196", "url": "https://www.uniprot.org/uniprotkb/Q9W196" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W196", "url": "https://www.uniprot.org/uniprotkb/Q9W196" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W196", "url": "https://www.uniprot.org/uniprotkb/Q9W196" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W196", "url": "https://www.uniprot.org/uniprotkb/Q9W196" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W196", "url": "https://www.uniprot.org/uniprotkb/Q9W196" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W196", "url": "https://www.uniprot.org/uniprotkb/Q9W196" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W196", "url": "https://www.uniprot.org/uniprotkb/Q9W196" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W196", "url": "https://www.uniprot.org/uniprotkb/Q9W196" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W196", "url": "https://www.uniprot.org/uniprotkb/Q9W196" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG3356", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3356", "resource": "KEGG Pathway" }, { "id": "R-DME-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K0E7-1", "protein_name": "Ubiquitin-protein ligase E3B", "gene_name": "Ube3b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFTVSQTSRAWFLDKARQAREERLEQKERERSAVLIQALVRSFLCRRRLHKDVRREIDEFFTADESGSSKRSALCIFKIARKLLFICKTTEDNERMEKLCRSILSSMDAENEPKVWYVSLALSKDLTLLWIKQIKSILWYCCELLGQLKPEILQDSRLITLYLTMLVTFTDTSTWKILRGKGESLRPALNHICANIMGHLNQRGFYSVLQVLLTRGLARPRPCLSKSTLTAAFTLALRPVVAAQFSDSLMRPFIIHIMSVPALVAHLSTMAPERLGVLESHDMLRKFIVFLRDRDRCQDACESLEGCHTLCLMGNLLHLGSLNLKMLEEETDGFVSLLTQMLCYCQKYVSQKKSNLTHWHPVLGWFSQSVDYGLNDSMYLITKQLQFLWGVPLIRIFFSDILSKKLLEPPEPVPAQPQPSSPQTVLPVKSLLKRAFQKSASVRNILKPVGGRRVDSTEVRKVCSICVLYQTSLTTLTQIRLQILTGLTYLDDLLPKLWAFICELGPHGGLKLFLECLNNDTGESKQLLAMLMLFCDCSRHLITILDDIEVYEEQISFKLEELVTISSFLNSFVFKMIWDGIVENAKGETLELFQSVHGWLMVLYERDCRRRFAPEDHWLRKDLKPGVLFQELDKDRKRAQLILLHIPHVVPHKNRVLLFRNMVIKEKEKLGLVETSSASPHVTHITIRRSRMLEDGYEQLRQLPQHAMKGAIRVKFVSDLGVDEAGIDQDGVFKEFLEEIIKRVFDPALNLFKTTSGDERLYPSPTSYIHENYLQLFEFVGKMLGKAVYEGIVVDVPFASFFLSQMLGHHHSVFYSSVDELPSLDSEFYKNLTSIKRYDGDVADLGLTLSYDEDVMGQLVCHELVPGGKTIPVTDENKISYIHLMAHFRMHTQIKNQTAALISGFRSIIKPEWIRMFSTPELQRLISGDNAEIDLEDLKKHTVYYGGFHGSHRVIVWLWDILASDFTPGERAMFLKFVTSCSRPPLLGFAYLKPPFSIRCVEVSDDQDTGDTLGSVLRGFFTIRKREPGGRLPTSSTCFNLLKLPNYSKKSVLREKLRYAISMNTGFELS", "length": 1070 }, "evidence": [ { "id": "SGD:S000003109", "url": "https://alliancegenome.org/gene/SGD:S000003109#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8N1YZY7-1", "protein_name": "Ubiquitin-protein ligase E3B", "gene_name": "ube3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFTATQTSKTQFLDKARVAREERKGHKEKERAATQIQALVRRFLCRCRLQKEIRKEVDDFIAVSDAGPTKRNALSIFKIARKLLFILSKDDKLRFEKLCRIILNSMDVENEPKVWYVSLALSKDLTILWLKQIKDVLWVSCEFLKKLKPDILQDNKLVTLYLTMLITFTDTSTWKIIRGKGEALKPALNRICENIMGHLNQKGFYSVLQILLTNGLARSRPSLSKGTLTAIFTLSLRPVIAAHFSDNLLRSFLLHVMSVPAFISHLNTLTPDCMITIQTHDLFRKFVLFLSREEQCLDICVCLEGSHTLCLLGNLIQLGYFNVKVLEQEAGHFVKDLTDMLSYCQRYVSQKKSNLTHWHPVLGWFSQTVDYGLNESMPLVTKQLQCLWGVPVICTLFCDVLSKKLETQDPTPPPAPQPSSLQNNLPVKNLFKRAFQKSASVRNILKPVGGKRVDSAEVQKVCSICVLYQTALTTLTQIRLQILTGLTYLDELLPKLWAFICELGPQGGLRLFLECLNNDTEESKQLLAMLMLFCDCSRHLITILDDIEVYEEQISFKMEELVTISSFLNTFVYKMVWDGILENAKGEKLDLFHSVHGWLMVLYERDCRRRFTPEDHWLRKDLKPSLLFQELEKGKKRAQLLLQYIPHVIPHKNRVLLFRNIVTKEKETLGLVETSSASPHVTHITIRRSRMLEDGYDQLRRLPVNSIKGVIRVKFVNDLGVDEAGIDQDGVFKEFLEEIIKKVFNPALNLFKTTSGNERLYPSPTSSIHENHLQLFEFVGKMLGKAMYEGIVVDVPFASFFLSQVLGHHHSTFYSSIDELPSLDSEFYKNLTSIKRYDGDVSDLGLTLSYDEEVMGQLVCHELIPGGKTMPVTNENKISYIHLMAHFRMHTQIKEQTAAFIRGFRSIINPEWLHMFSTPEVQRLISGDNAEIDLDDLKKHTVYYGGFHSSHRVILWLWDILSSDFTPDERAMFLKFVTSCSRPPLLGFAYLKPPFSIRCVEVSDDQDTGDTLGSVLRGFFTIRKKEPGGRLPTSSTCFNLLKLPNYSKKSILRDKLRYAISMNTGFELS", "length": 1069 }, "evidence": [ { "id": "SGD:S000003109", "url": "https://alliancegenome.org/gene/SGD:S000003109#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V1A0X2-1", "protein_name": "Ubiquitin-protein ligase E3C", "gene_name": "UBE3C", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MFSFEGDFKTRPKVSLGGASKKEEKASLLHRTQEERRKREEERRRLKNAIIIQSFVRGYRDRNHQYSTQRSEFDRCANLAQSGGTFSTANGANLTLLVRQLLFFYRQNEDSKRLIWMCQNLIKQSSQFVKQLDGPDRLTCLFQIKRLLGLCCRLLQNCNDDSLNVALPMRMLEVFSSENTYLPVLQDVSYVTSLIEQILHYMIQKGYYRSLYLLINSKLPSSIEYSDVSRVPLAKILLENVLKPLHFTYSSCPEGARQQIFAAFTEEFVAAPFTDQIFHFIIPALADVQIVFPYEFFLNALLLAENGCSRKSDRAPWLFYFVLTVGETYLGSLSEEGLLVYLRVLQAFLSQLPVSSAGTSCQDANSDSEDEDEEISKMTTTPGDGRISVQYITEECLKKLDTKQQTNTLLNMVWRDSASEEVFTLMASICHTLMVQHRMMVPKVRLLYSLAFNARFLRHLWYLISSMTTRMITGSMVPLLQVISRGSPMSLDDSSRIIPLFYLFSSLFSHSLISIHDNEFFGDPIEVVGQRQSSMMPFTLEELVILSRCLRDACLGIIKLAYPETKPEVREEYIAAFRSVGVTKNTEMQQCIQTEQKRWIQLFKVITNLVKMLKARDTRRNFCPPNHWLSEQENIKADKVTQLYVPSARHVWRVRRMGRIGPLQSTLDVGLEPAPLSVSEERQLAILTELPFVVPFEERVKIFQRLIYADKQEVQGDGPFLDGINVTIRRNYIYEDAYDKLSPENEPDLKKRIRVHLLNAHGLDEAGIDGGGIFREFLNELLKSGFNPNQGFFKTTNEGLLYPNPAAQMLVGDSYARHYYFLGRMLGKALYENMLVELPFASFFLSKLLGTSADVDIHHLASLDPEMYKNLLFLKSYEGDVEELGLNFTVVNNDLGEAQVVELKPGGKDIPVTSANRIAYIHLVADYRLNKQIRQHCLAFRQGLANVVNLEWLRMFDQQEIQVLISGAQVPISLDDLKSFTNYSGGYAADHPVIKTFWRVVERFTDEEKRKLLKFVTSCSRPPLLGFKELYPAFCIHNGGSDLDRLPTASTCMNLLKLPEFYDENLMRSKLLYAIECAAGFELS", "length": 1084 }, "evidence": [ { "id": "Q9W196", "url": "https://omabrowser.org/oma/group/Q9W196/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZHB7-1", "protein_name": "Ubiquitin-protein ligase E3C", "gene_name": "Ube3c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSFEGDFKTRPKVSLGGASRKEEKASLLHRTQEERRKREEERRRLKNAVIIQSFIRGYRDRKQQYFTQRSAFDQCADSAQPGGTFRIADGPALTLLVRQLLFFYKQSEDSKRLIWLYQNLIKHSSLFVKQLDGSERLTCLFQLKRLMSLCCRLLQNCSDDSLNVALPMRMLEVFSSENTYLPVLQDSSYVVSVIEQILHYMVHSGYYRSLYLLINSKLPSSIEYSDLSRVPMAKTLLENVLKPLHFTYSSCPEGARHQVFSAFTEEFLGAPFTDQIYHFIIPALADTQTVFPYEPFLNALLLLESRSSKRSSGVPWLFYFVLTIGENYLGALSEDGLLVYLRVLQTFLSQLPASPTGVGRPDPTSDSEDDNEETDQPTSPEDGRVSAPYITEECLRKLDTKQQTNTLLNLVWRDSASEEVFTRMASICHTLMVQHRMMVPKVRLLYSLAFNARFLRHLWFLISSMTTQMITGSMVPLLQVISRGSPMSFEDSSRIIPLFYLFSSLFSHSLISIHDNEFFGDPIEVVGQRQLSMMPFTLEELILLSRCLRDACLGIIKLAYPETKPEVREEYVSAFQSIGVTTNSEMQHCIQMEQKRWVQLFKVITNLVKMLKSRDTRRNFCPPNHWLSEQEDIKADKVTQLYVPASRHVWRFRRMGRIGPLQSTLEVGLESPPLSVSEERQLAILTELPFVVPFEERVKIFQRLIYADKQEVQGDGPFLDGINVTIRRNYIYEDAYDKLSPENEPDLKKRIRVHLLNAHGLDEAGIDGGGIFREFLNELLKSGFNPNQGFFKTTNEGLLYPNPAAQMLVGDSFARHYYFLGRMLGKALYENMLVELPFAGFFLSKLLGTSADVDIHHLASLDPEVYKNLLFLKSYEEDVEELGLNFTVVNNDLGEAQVVELKFGGKDIPVTGANRIAYIHLVADYRLNKQIRPHCLAFRQGLANVVSLEWLRMFDQQEIQVLISGAQVPVSLEDLKSFTNYSGGYSADHPVIKIFWRVVEGFTDEEKRKLLKFVTSCSRPPLLGFKELYPAFCIHNGGSDLERLPTASTCMNLLKLPEFYDEALLRSKLLYAIECAAGFELS", "length": 1083 }, "evidence": [ { "id": "MGI:2140998", "url": "https://alliancegenome.org/gene/MGI:2140998#orthology", "database": "AGR" }, { "id": "HGNC:16803", "url": "https://alliancegenome.org/gene/HGNC:16803#orthology", "database": "AGR" }, { "id": "FB:FBgn0034989", "url": "https://alliancegenome.org/gene/FB:FBgn0034989#orthology", "database": "AGR" }, { "id": "RGD:1559986", "url": "https://alliancegenome.org/gene/RGD:1559986#orthology", "database": "AGR" }, { "id": "SGD:S000003109", "url": "https://alliancegenome.org/gene/SGD:S000003109#orthology", "database": "AGR" }, { "id": "Q9W196", "url": "https://omabrowser.org/oma/group/Q9W196/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SHV8-1", "protein_name": "Ubiquitin-protein ligase E3C", "gene_name": "UBE3C", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFSFEGDFKTRPKVSLGGASRKEEKASLLHRTQEERRKREEERRRLKNAIIIQSFIRGYRDRKQQCSTQRSAFDRCANLSQAGGAFSIASGPNLTLLVRQLLFFYRQSEDSQRLIWMYQNLIKHSSLFVQQLDGSERLTCLFQIKRLMSLCCRLLQSCNDDSLNVALPMRMLEVFSSENTYLPVLRDASYVVSVVEQILHYMIQNGYYRSLYLLINSKLPSSIEYSDISRVPIAKILLENVLKPLHFTYNSCPEGARQQVFTAFTKEVLAAPFTEQVFRFVIPALADAQTLFPYEPFLNALVSAERRGPEASAGAPWLFYFVLTVGENYLGTLSEDGLLVYLRVLQAFLAQLPVSAAGTSCQDSASDSEDESEETDKQPNTPEGGRLSVPYITEECLKKLDTKQQTNTLLNLVWRDSASEEAFTLMAAVCHTLMVQHRVMVPKARLLYSLAFNARFLRHLWFLISSMTTRMITGSVVPLLQVMSRGSPMSFEDSSRIIPLFYLFSSLFSHSLISIHDNEFFGDPIEVAGQRPSSMMPFTLEELVMLSRCLRDACLGIIKLAYPETKPEVREEYVTAFQSVGVTTNSEMQQCIQMEQKRWIQLFKVITNLVKMLKSRDTRRNFCPPNHWLSEQEDIKADKVTQLYVPASRNAWRSRRMGRIGPLRSTLDVGVESPPLSVSEERQLAVLTELPFVVPFEERVKIFQRLIYADKQEVQGDGPFLDGINVTIRRNYIYEDAYDKLSPENEPDLKKRIRVHLLNAHGLDEAGIDGGGIFREFLNELLKSGFNPNQGFFKTTNEGLLYPNPAAHMLVGDSFARHYYFLGRMLGKALYENMLVELPFASFFLSKLLGTSADVDIHHLASLDPEVYRNLLFLKSYEGDVEELGLNFTVVNNDLGEAQVVELKYGGKDIPVTSANRIAYIHLVADYRLNRQIRQHCLAFRQGLANVLNLEWLRMFDQQEIQVLISGAQVPISLEDLKSFTNYSGGYSADHPVIRAFWRVVEGFTDEEKRKLLKFVTSCSRPPLLGFKELYPAFCIHNGGSDLERLPTASTCMNLLKLPEFHDEALLRSKLLYAIECAAGFELS", "length": 1084 }, "evidence": [ { "id": "Q9W196", "url": "https://omabrowser.org/oma/group/Q9W196/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P53119-1", "protein_name": "E3 ubiquitin-protein ligase HUL5", "gene_name": "HUL5", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLNFTGQTRRRNVNLGNRTRNSKKDLLEKAKRERERRAQDKLKEDASKTIQKSIRRHFSNVRLFKNTFTSSQLVHMIPAYGGKLIYYISQYDLQQLLKLSHNFLSSYPNSLGNRQLLSLLKLYQDDALVAETLSDLNMDCPTVDEFLDSLSVYLCRASFLSYSSASKLADVIEAWEVMHSSASISIFSISIGSYEKRPFALQFYCILAERNLLPQLINTNPILWDNMAKTYSHCSKGGQKNIAKLLIPNFNNHIAPSVLRSDNDYVLKFYEKAFIDEVIATTANYVSDEDHVKNLMCYIASSPNQSCKNSVLITLLSNKDFVRRLSWEFFHTKFNASKTEAHPLFSVLAQLIDMHLLISTDRELLDYNSVIPIEELKKFTSTLKDFTFRQYWELPKSERNPMLKEAVPLLSKVYERDSRLHFLSTENNPTYWENSEKQFLNLRFYEELQEYEDLYREHLEEESDEDMEKEIDLDKERPPLKSLLLNKMKKRLKSSLRFRKLEILLELPFFIPFEERVDLFYMFIALDKKRLSLDDDHNLINMFTPWASTGMRKQSAIISRDNVLEDAFNAFNSIGERFKASLDVTFINEFGEEAGIDGGGITKEFLTTVSDEGFKDPKHELFRTNDRYELYPSVVYDATKLKYIWFLGKVVGKCLYEHVLIDVSFADFFLKKLLNYSNGFLSSFSDLGSYDSVLYNNLIKLLNMTTDEIKSLDLTFEIDEPESSAKVVDLIPNGSKTYVTKDNVLLYVTKVTDYKLNKRCFKPVSAFHGGLSVIIAPHWMEMFNSIELQMLISGERDNIDLDDLKSNTEYGGYKEEDQTIVDFWEVLNEFKFEEKLNFLKFVTSVPQAPLQGFKALDPKFGIRNAGTEKYRLPTASTCVNLLKLPDYRNKTILREKLLYAINSGARFDLS", "length": 910 }, "evidence": [ { "id": "MGI:2140998", "url": "https://alliancegenome.org/gene/MGI:2140998#orthology", "database": "AGR" }, { "id": "HGNC:16803", "url": "https://alliancegenome.org/gene/HGNC:16803#orthology", "database": "AGR" }, { "id": "FB:FBgn0034989", "url": "https://alliancegenome.org/gene/FB:FBgn0034989#orthology", "database": "AGR" }, { "id": "RGD:1559986", "url": "https://alliancegenome.org/gene/RGD:1559986#orthology", "database": "AGR" }, { "id": "SGD:S000003109", "url": "https://alliancegenome.org/gene/SGD:S000003109#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q15386-1", "protein_name": "Ubiquitin-protein ligase E3C", "gene_name": "UBE3C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFSFEGDFKTRPKVSLGGASRKEEKASLLHRTQEERRKREEERRRLKNAIIIQSFIRGYRDRKQQYSIQRSAFDRCATLSQSGGAFPIANGPNLTLLVRQLLFFYKQNEDSKRLIWLYQNLIKHSSLFVKQLDGSERLTCLFQIKRLMSLCCRLLQNCNDDSLNVALPMRMLEVFSSENTYLPVLQDASYVVSVIEQILHYMIHNGYYRSLYLLINSKLPSSIEYSDLSRVPIAKILLENVLKPLHFTYNSCPEGARQQVFTAFTEEFLAAPFTDQIFHFIIPALADAQTVFPYEPFLNALLLIESRCSRKSGGAPWLFYFVLTVGENYLGALSEEGLLVYLRVLQTFLSQLPVSPASASCHDSASDSEEESEEADKPSSPEDGRLSVSYITEECLKKLDTKQQTNTLLNLVWRDSASEEVFTTMASVCHTLMVQHRMMVPKVRLLYSLAFNARFLRHLWFLISSMSTRMITGSMVPLLQVISRGSPMSFEDSSRIIPLFYLFSSLFSHSLISIHDNEFFGDPIEVVGQRQSSMMPFTLEELIMLSRCLRDACLGIIKLAYPETKPEVREEYITAFQSIGVTTSSEMQQCIQMEQKRWIQLFKVITNLVKMLKSRDTRRNFCPPNHWLSEQEDIKADKVTQLYVPASRHVWRFRRMGRIGPLQSTLDVGLESPPLSVSEERQLAVLTELPFVVPFEERVKIFQRLIYADKQEVQGDGPFLDGINVTIRRNYIYEDAYDKLSPENEPDLKKRIRVHLLNAHGLDEAGIDGGGIFREFLNELLKSGFNPNQGFFKTTNEGLLYPNPAAQMLVGDSFARHYYFLGRMLGKALYENMLVELPFAGFFLSKLLGTSADVDIHHLASLDPEVYKNLLFLKSYEDDVEELGLNFTVVNNDLGEAQVVELKFGGKDIPVTSANRIAYIHLVADYRLNRQIRQHCLAFRQGLANVVSLEWLRMFDQQEIQVLISGAQVPISLEDLKSFTNYSGGYSADHPVIKVFWRVVEGFTDEEKRKLLKFVTSCSRPPLLGFKELYPAFCIHNGGSDLERLPTASTCMNLLKLPEFYDETLLRSKLLYAIECAAGFELS", "length": 1083 }, "evidence": [ { "id": "MGI:2140998", "url": "https://alliancegenome.org/gene/MGI:2140998#orthology", "database": "AGR" }, { "id": "HGNC:16803", "url": "https://alliancegenome.org/gene/HGNC:16803#orthology", "database": "AGR" }, { "id": "FB:FBgn0034989", "url": "https://alliancegenome.org/gene/FB:FBgn0034989#orthology", "database": "AGR" }, { "id": "RGD:1559986", "url": "https://alliancegenome.org/gene/RGD:1559986#orthology", "database": "AGR" }, { "id": "SGD:S000003109", "url": "https://alliancegenome.org/gene/SGD:S000003109#orthology", "database": "AGR" }, { "id": "Q9W196", "url": "https://omabrowser.org/oma/group/Q9W196/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q1LY19-1", "protein_name": "Ubiquitin-protein ligase E3C", "gene_name": "ube3c", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFSFEGDFRRTPKVSLGGASRKEEKASLLHRTQEERRKREDERKRLKNAIIIQSYIRGYQDRKQQYAIQRGSFDHCVCQCQSGSGPQLTDSAILSQLVRQLLFFYRLSEDRPRMIWMCQCLVKHHAQFVKLLTGPERQICLFQIKRLLGHCCRLLQSCEDDSLNVAVPMRMLEVFSSERTYLPFLQDENCVTSLIEQILHYMVQKGFYRSLYVLVNHKLPSSLEYSDTPSIPLAQTLLEHTLKPLHFTYSSCPPDTRQFVFSAFTEEFISAPFTEQIYHFFVPALSDPKLAFPFQNFLWSLQATIASSVQARTQAPWLFYFVLSVGESGLSSLSEEGLLLYLNALQTLLPLLPVTECNSRADINSDSEDEEEMTVQHPAAPDGSWISVHYITEECVQKLDTKQQTNALLTLVWRDSASEDVFTMMASICHTLMVQHRMMVPRVRLLYSLAFNARFLRHLWYLITSMKTKMITGSMVPLLQVMSRGSPMTLEDSNRIIPLFYLFSSLFSHSLISVHDSEFFGSSADGQSQSSMMPFSLGELVTLSRCLRDACLGIIKLAYPETKTEHKEEYVAAFRSVGVKTNSQVQQRIQAQQKRWVQLFKVITNLVKMLKARDIRRPFCPSGHWLSDEVNIRADKVTQLYVPSARHMWRTRRMGRIGPLQSTLDVGLEPPPLSVSEERHLAILTELPFVVPFEERVKIFQKLIYADKREVQGEGPFLDGVNVTIRRNYIYEDAYDKLSPENEPDLKKRIRVHLLNAHGLDEAGIDGGGIFREFLNELLKSGFNPNQGFFKTTNEGLLYPSPTAEMLVGESFTRHYYFLGRILGKALYENMLVELPFASFFLSKLLGTSADVDIHHLASLDPEMYRNLLFLKSYEGDVEDLGLNFTVVNNDLGEAQVVELKPGGKDIPVTTANRIAYIHLVADYRLNKQIRAHCLAFRQGLANVVNLEWLRMFDQQEIQVLVSGAHVPICLEDLKRFTNYSGGYSATHPVIKIFWDVVESFSDEEKRKLLKFVTSCSRPPLLGFKELYPAFCIHNGGTDLERLPTASTCMNLLKLPEFCDPQLMRNKLLYAIESSAGFELS", "length": 1081 }, "evidence": [ { "id": "MGI:2140998", "url": "https://alliancegenome.org/gene/MGI:2140998#orthology", "database": "AGR" }, { "id": "HGNC:16803", "url": "https://alliancegenome.org/gene/HGNC:16803#orthology", "database": "AGR" }, { "id": "Q9W196", "url": "https://omabrowser.org/oma/group/Q9W196/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q7Z3V4-1", "protein_name": "Ubiquitin-protein ligase E3B", "gene_name": "UBE3B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFTLSQTSRAWFIDRARQAREERLVQKERERAAVVIQAHVRSFLCRSRLQRDIRREIDDFFKADDPESTKRSALCIFKIARKLLFLFRIKEDNERFEKLCRSILSSMDAENEPKVWYVSLACSKDLTLLWIQQIKNILWYCCDFLKQLKPEILQDSRLITLYLTMLVTFTDTSTWKILRGKGESLRPAMNHICANIMGHLNQHGFYSVLQILLTRGLARPRPCLSKGTLTAAFSLALRPVIAAQFSDNLIRPFLIHIMSVPALVTHLSTVTPERLTVLESHDMLRKFIIFLRDQDRCRDVCESLEGCHTLCLMGNLLHLGSLSPRVLEEETDGFVSLLTQTLCYCRKYVSQKKSNLTHWHPVLGWFSQSVDYGLNESMHLITKQLQFLWGVPLIRIFFCDILSKKLLESQEPAHAQPASPQNVLPVKSLLKRAFQKSASVRNILRPVGGKRVDSAEVQKVCNICVLYQTSLTTLTQIRLQILTGLTYLDDLLPKLWAFICELGPHGGLKLFLECLNNDTEESKQLLAMLMLFCDCSRHLITILDDIEVYEEQISFKLEELVTISSFLNSFVFKMIWDGIVENAKGETLELFQSVHGWLMVLYERDCRRRFTPEDHWLRKDLKPSVLFQELDRDRKRAQLILQYIPHVIPHKNRVLLFRTMVTKEKEKLGLVETSSASPHVTHITIRRSRMLEDGYEQLRQLSQHAMKGVIRVKFVNDLGVDEAGIDQDGVFKEFLEEIIKRVFDPALNLFKTTSGDERLYPSPTSYIHENYLQLFEFVGKMLGKAVYEGIVVDVPFASFFLSQLLGHHHSVFYSSVDELPSLDSEFYKNLTSIKRYDGDITDLGLTLSYDEDVMGQLVCHELIPGGKTIPVTNENKISYIHLMAHFRMHTQIKNQTAALISGFRSIIKPEWIRMFSTPELQRLISGDNAEIDLEDLKKHTVYYGGFHGSHRVIIWLWDILASDFTPDERAMFLKFVTSCSRPPLLGFAYLKPPFSIRCVEVSDDQDTGDTLGSVLRGFFTIRKREPGGRLPTSSTCFNLLKLPNYSKKSVLREKLRYAISMNTGFELS", "length": 1068 }, "evidence": [ { "id": "SGD:S000003109", "url": "https://alliancegenome.org/gene/SGD:S000003109#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80U95-1", "protein_name": "Ubiquitin-protein ligase E3C", "gene_name": "Ube3c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSFEGDFKTRPKVSLGGASRKEEKASLLHRTQEERRKREEERRRLKNAVIIQSFIRGYRDRKQQYFIQRSAFDQCTDSAQPGGTFCLADGPNLTLLVRQLLFFYKQSEDSKRLIWLYQNLIKHSSLFVKQLDGSERLTCLFQIKRLMSLCCRLLQNCSDDSLNVALPMRMLEVFTSENTYLPVLQDSSYVVSVIEQILHYMVHSGYYRSLYLLINSKLPSSIEYSDLSRVPIAKILLENVLKPLHFTYSSCPEASRHQVFSAFTEEFLGAPFTDQIFHFVIPAFADAQTVFPYEPFLNALLLLESQSSKRCSGVPWLFYFVLTVGENYLGALSEDGLLVYLRVLQTFLSQLPASPTGTGCPDSTSDSEDDNEETDQPNSPEDGRVSAPYITEECLRKLDTKQQTNTLLNLVWRDSASEEVFTRMASICHTLMVQHRMMVPKVRLLYSLAFNARFLRHLWFLISSMTTQMITGSMVPLLQLISRGSPMSFEDSSRIIPLFYLFSSLFSHSLISIHDNEFFGDPIEVVGQRQSSMMPFTLEELILLSRCLRDACLGIIKLAYPETKPEVREEYVTAFQSIGVTTNSEMQQCIQMEQKRWVQLFKVITNLVKMLKSRDTRRNFCPPNHWLSEQEDIKADKVTQLYVPASRHVWRFRRMGRIGPLQSTLEVGLESLPLSVSEERQLAILTELPFVVPFEERVKIFQRLIYADKQEVQGDGPFLDGINVTIRRNYIYEDAYDKLSPENEPDLKKRIRVHLLNAHGLDEAGIDGGGIFREFLNELLKSGFNPNQGFFKTTNEGLLYPNPAAQMLVGDSFARHYYFLGRMLGKALYENMLVELPFAGFFLSKLLGTSADVDIHHLASLDPEVYRNLLFLKSYEEDVEELGLNFTVVNNDLGEAQVVELKFGGKDIPVTGANRIAYIHLVADYRLNKQIRPHCLAFRQGLANVVSLEWLRMFDQQEIQVLISGAQVPVSLEDLKSFTNYSGGYSADHPVIKIFWRVVEGFTDEEKRKLLKFVTSCSRPPLLGFKELYPAFCIHNGGSDLERLPTASTCMNLLKLPEFYDEALLRSKLLYAIECAAGFELS", "length": 1083 }, "evidence": [ { "id": "MGI:2140998", "url": "https://alliancegenome.org/gene/MGI:2140998#orthology", "database": "AGR" }, { "id": "HGNC:16803", "url": "https://alliancegenome.org/gene/HGNC:16803#orthology", "database": "AGR" }, { "id": "FB:FBgn0034989", "url": "https://alliancegenome.org/gene/FB:FBgn0034989#orthology", "database": "AGR" }, { "id": "RGD:1559986", "url": "https://alliancegenome.org/gene/RGD:1559986#orthology", "database": "AGR" }, { "id": "SGD:S000003109", "url": "https://alliancegenome.org/gene/SGD:S000003109#orthology", "database": "AGR" }, { "id": "Q9W196", "url": "https://omabrowser.org/oma/group/Q9W196/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9ES34-1", "protein_name": "Ubiquitin-protein ligase E3B", "gene_name": "Ube3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFTVSQTSRAWFIDRARQAREERLVQKERERSAVTIQALVRSFLCRRRLHRDIRKEIDEFFSADESGSSKRSALCIFKIARRLLFICKTTEDSERLEKLCRSILNSMDAENEPKVWYVSLALSKDLTLLWIKQIKSILWHCCELLGQLKPEILQDSRLITLYLTMLVTFTDTSTWKILRGKGESLRPALNHICANIMGHLNQRGLYSVLQVLLTRGLARPRPCLSKGMLTAAFSLALRPVVAAQFSDNLMRPFIIHVMSVPALVAHLSTVAPERLGVLESHDMLRKFIVFLRDRDRCRDACESLEGCHTLCLMGNLLHLGSLSLRLLEEEMDGFVSALTQMLCYCQKYVAQKKSNLTHWHPVLGWFSQPVDYGLNDSMYLITKQLQFLWAVPLIRILFSDILSRKLLEHAEPAPVQPQPSSPQTVLPVKSLLKRAFQKSASVRNILRPVGGRRVDSAEVRKVCNICVLYQTSLTTLTQIRLQILTGLTYLDDLLPKLWAFICELGPHGGLKLFLECLNNDTGESKQLLAMLMLFCDCSRHLITILDDIEVYEEQISFKLEELVTISSFLNSFVFKMIWDGIVENAKGETLELFQSVHGWLMVLYERDCRRRFAPEDHWLRRDLKPGVLFQELDKDRRRAQLVLQHIPHVVPHKNRVLLFRNMVIKEKEKLGLVETSSASPHVTHITIRRSRMLEDGYEQLRQLSQHAMKGVIRVKFVNDLGVDEAGIDQDGVFKEFLEEIIKRVFDPALNLFKTTSGDERLYPSPTSYIHENYLQLFEFVGKMLGKAVYEGIVVDVPFASFFLSQMLGHHHSVFYSSVDELPSLDSEFYKNLTSIKRYDGDIADLGLTLSYDEDVMGQLVCHELVPGGKTIPVTDENKISYIHLMAHFRMHTQIKNQTAALISGFRSIIKPEWIRMFSTPELQRLISGDNAEIDLEDLKKHTVYYGGFHGSHRVIIWLWDILASDFTPEERAMFLKFVTSCSRPPLLGFAYLKPPFSIRCVEVSDDQDTGDTLGSVLRGFFTIRKREPGGRLPTSSTCFNLLKLPNYSKKSVLREKLRYAISMNTGFELS", "length": 1070 }, "evidence": [ { "id": "SGD:S000003109", "url": "https://alliancegenome.org/gene/SGD:S000003109#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VSS9-1", "protein_name": "Ubiquitin-protein ligase E3B", "gene_name": "NM_140022.1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFAQNQKASFLEQTKAAREERALEKRREQAAILLQSTLKGYAARRKYQKRIILDFDAMFTENHDDKDAELELVASNVYPVLRRYLTQIRLDKSDVRARERLERICRYIIKAMESENTKLSYAALCLFKERSLPWIAHIKILLTNCLTLLPELKPENHADSLSLALFLHTLVVFTAPKSWAILRNAQFEKLQPAMQKICCNIQGHLVQHDFYKIMRLVLIRGTVREELSVKPVTLVAIITLCLRPLIDGNFSRNLLAKFLSEILSVPALIYHLQQSVPQCLEQFSSMGLLKKALSISGDVQWFEEFGTSMPGTKSLAFLGNIVNLFNIDGQGESKELAYPLLTETTTSLLELIPNTVTTKGVFTQWHELLGWHTPGPEPAQNQNVALIKKQFHMLWDHRCIKLLLGDLLKQINLNYERIEFQSPQQPSISNLLRRALERSSTRGVNLMGVASSKQSKQQWRKLDSAEVVQVSRICGMYYAALNTLSQMKLDILTGICYSDNVLYDIWLLITSLGPNCGMKEYLELLKSETNLQKPQTAMLMLFCDCMTHYVTILDEHEMYTEQNPFKLNDYVLLTYFLNNILYKLINDNLLAGAKNIVQHPVFLSLHTLMLCLYRRDCRRPFTPPKHWLIPEVKPSTFINDLEKAKRNAMLLLAKMPHIIPHEDRVKLFRKFVQNEKAVMGLTESACASPRSALIVIHRDRIVEDGYRQLAAQPTQALKGVIRVRFINQQGLHEAGIDQDGVFKEFLEETIKKVFDPSLNLFKTTSDQRLYPSPISYVQDNHLELFEFVGRMLGKAVYEGIVVDVPFASFFLSQLLGQTQQALYSCMDELPSLDNELYRSLTFIKHYKQDVSDLNLTFSVDQDVMGKIVTLALHPGGKARVVNDHNKLVYIHYMAFFHMNTQIREQTIAFNRGFRSIVNPEWLSLFSPPELQRLISGDTSPLDLKDLQKHTHYYGGFHDTHQVVCWLWDILAKDFTEEERKLFLKFVTSCSKPPLLGFAHLEPPFSIRCVEVSDDEDTGDTIGSVIRGFFAIRKKDPLNRLPTSSTCFNLLKLPNYQKKSTLRDKLRYAVSSNTGFELS", "length": 1078 }, "evidence": [ { "id": "SGD:S000003109", "url": "https://alliancegenome.org/gene/SGD:S000003109#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9W196", "url": "https://www.uniprot.org/uniprotkb/Q9W196" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9W196", "url": "https://www.uniprot.org/uniprotkb/Q9W196" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "Q9W196", "url": "https://www.uniprot.org/uniprotkb/Q9W196" } ], "pmid": "" }, { "name": "ubiquitin conjugating enzyme binding", "id": "GO:0031624", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031624", "evidence": [ { "database": "UniProtKB", "id": "Q9W196", "url": "https://www.uniprot.org/uniprotkb/Q9W196" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "Q9W196", "url": "https://www.uniprot.org/uniprotkb/Q9W196" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of signal transduction", "id": "GO:0009966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009966", "evidence": [ { "database": "UniProtKB", "id": "Q9W196", "url": "https://www.uniprot.org/uniprotkb/Q9W196" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "Q9W196", "url": "https://www.uniprot.org/uniprotkb/Q9W196" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "Q9W196", "url": "https://www.uniprot.org/uniprotkb/Q9W196" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 260, "end_pos": 262, "annotation": "n_glycosylation_sequon" }, { "start_pos": 446, "end_pos": 448, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-DME-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VJ14-1", "Q9VUV7-1", "Q9VXE8-1", "Q9VY98-1", "Q9W4W4-1", "Q9XYW6-1", "M9MRI4-1", "O76924-1", "P35128-1", "P52485-1", "Q9VE61-1", "Q9VI55-1", "Q9VSF3-1", "Q9VX25-1", "X2JF73-1", "P21461-1", "P52486-1", "Q8T3Y0-1", "Q9V853-1", "Q9VTY6-1", "Q9VVI3-1", "Q9VW09-1", "Q9Y0H4-1", "Q9VEJ4-1", "Q9VFC4-1", "Q9VSS9-1", "Q9W326-1", "Q9W3V3-1", "M9PBE2-1", "Q9VR91-1", "A0A0B4KFY0-1", "Q9VN58-1", "Q9VP20-1", "Q9VQ67-1", "Q9VSK2-1", "A1Z8B5-1", "Q9VQ00-1", "Q9VTH1-1", "P25153-1", "P25867-1", "P52487-1", "Q7K738-1", "Q7KTX7-1", "Q9VHI7-1", "Q9VX91-1", "Q9VZ73-1", "Q9W196-1" ], "evidence": [ { "id": "R-DME-983140", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-983140" } ] }, { "id": "R-DME-983147", "name": "Release of E3 from polyubiquitinated substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VJ14-1", "Q9VUV7-1", "Q9VY98-1", "Q9W4W4-1", "Q9XYW6-1", "M9MRI4-1", "O76924-1", "Q9VE61-1", "Q9VI55-1", "X2JF73-1", "P21461-1", "Q8T3Y0-1", "Q9V853-1", "Q9VVI3-1", "Q9VW09-1", "Q9Y0H4-1", "Q9VFC4-1", "Q9VSS9-1", "Q9W326-1", "Q9W3V3-1", "M9PBE2-1", "Q9VR91-1", "A0A0B4KFY0-1", "Q9VN58-1", "Q9VP20-1", "Q9VQ67-1", "Q9VSK2-1", "Q9VTH1-1", "Q7KTX7-1", "Q9VHI7-1", "Q9VX91-1", "Q9W196-1" ], "evidence": [ { "id": "R-DME-983147", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-983147" } ] }, { "id": "R-DME-983156", "name": "Polyubiquitination of substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VJ14-1", "Q9VUV7-1", "Q9VXE8-1", "Q9VY98-1", "Q9W4W4-1", "Q9XYW6-1", "M9MRI4-1", "O76924-1", "P35128-1", "P52485-1", "Q9VE61-1", "Q9VI55-1", "Q9VSF3-1", "Q9VX25-1", "X2JF73-1", "P21461-1", "P52486-1", "Q8T3Y0-1", "Q9V853-1", "Q9VTY6-1", "Q9VVI3-1", "Q9VW09-1", "Q9Y0H4-1", "Q9VEJ4-1", "Q9VFC4-1", "Q9VSS9-1", "Q9W326-1", "Q9W3V3-1", "M9PBE2-1", "Q9VR91-1", "A0A0B4KFY0-1", "Q9VN58-1", "Q9VP20-1", "Q9VQ67-1", "Q9VSK2-1", "A1Z8B5-1", "Q9VQ00-1", "Q9VTH1-1", "P25153-1", "P25867-1", "P52487-1", "Q7K738-1", "Q7KTX7-1", "Q9VHI7-1", "Q9VX91-1", "Q9VZ73-1", "Q9W196-1" ], "evidence": [ { "id": "R-DME-983156", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-983156" } ] }, { "id": "R-DME-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VJ14-1", "Q9VUV7-1", "Q9VXE8-1", "Q9VY98-1", "Q9W4W4-1", "Q9XYW6-1", "M9MRI4-1", "O76924-1", "P35128-1", "P52485-1", "Q9VE61-1", "Q9VI55-1", "Q9VSF3-1", "Q9VX25-1", "X2JF73-1", "P21461-1", "P52486-1", "Q8T3Y0-1", "Q9V853-1", "Q9VTY6-1", "Q9VVI3-1", "Q9VW09-1", "Q9Y0H4-1", "Q9VEJ4-1", "Q9VFC4-1", "Q9VSS9-1", "Q9W326-1", "Q9W3V3-1", "M9PBE2-1", "Q9VR91-1", "A0A0B4KFY0-1", "Q9VN58-1", "Q9VP20-1", "Q9VQ67-1", "Q9VSK2-1", "A1Z8B5-1", "Q9VQ00-1", "Q9VTH1-1", "P25153-1", "P25867-1", "P52487-1", "Q7K738-1", "Q7KTX7-1", "Q9VHI7-1", "Q9VX91-1", "Q9VZ73-1", "Q9W196-1" ], "evidence": [ { "id": "R-DME-983157", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-983157" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A0B4KFY0", "gene_name": "dnr1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A0B4KFY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFY0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A0B4KFY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KFY0" } ] } ] }, { "uniprot_ac": "A1Z8B5", "gene_name": "Ube2W", "activity": [ { "ec_number": "2.3.2.25", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-N-terminal-amino acid = [E1 ubiquitin-activating enzyme]-L-cysteine + N-terminal-ubiquitinyl-[acceptor protein].", "evidence": [ { "id": "A1Z8B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1Z8B5" } ] }, { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A1Z8B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1Z8B5" } ] }, { "ec_number": "2.3.2.25", "activity": "", "evidence": [ { "id": "A1Z8B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1Z8B5" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A1Z8B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1Z8B5" } ] } ] }, { "uniprot_ac": "M9MRI4", "gene_name": "Trim9", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "M9MRI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9MRI4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "M9MRI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9MRI4" } ] } ] }, { "uniprot_ac": "M9PBE2", "gene_name": "Hakai", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "M9PBE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9PBE2" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "M9PBE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9PBE2" } ] } ] }, { "uniprot_ac": "O76924", "gene_name": "ari-2", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "O76924", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O76924" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "O76924", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O76924" } ] } ] }, { "uniprot_ac": "P21461", "gene_name": "sina", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "P21461", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21461" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "P21461", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21461" } ] } ] }, { "uniprot_ac": "P25153", "gene_name": "Ubc6", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "P25153", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P25153" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "P25153", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P25153" } ] } ] }, { "uniprot_ac": "P25867", "gene_name": "eff", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "P25867", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P25867" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "P25867", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P25867" } ] } ] }, { "uniprot_ac": "P35128", "gene_name": "ben", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "P35128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35128" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "P35128", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P35128" } ] } ] }, { "uniprot_ac": "P52485", "gene_name": "Ubc2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "P52485", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52485" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "P52485", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52485" } ] } ] }, { "uniprot_ac": "P52486", "gene_name": "Ubc4", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "P52486", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52486" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "P52486", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52486" } ] } ] }, { "uniprot_ac": "P52487", "gene_name": "Ubc84D", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "P52487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52487" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "P52487", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P52487" } ] } ] }, { "uniprot_ac": "Q7K738", "gene_name": "Ubc10", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q7K738", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7K738" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q7K738", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7K738" } ] } ] }, { "uniprot_ac": "Q7KTX7", "gene_name": "park", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "Q7KTX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7KTX7" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "Q7KTX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7KTX7" } ] } ] }, { "uniprot_ac": "Q8T3Y0", "gene_name": "sinah", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q8T3Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8T3Y0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q8T3Y0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8T3Y0" } ] } ] }, { "uniprot_ac": "Q9V853", "gene_name": "Smurf", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q9V853", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9V853" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "Q9V853", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9V853" } ] } ] }, { "uniprot_ac": "Q9VE61", "gene_name": "", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q9VE61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VE61" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q9VE61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VE61" } ] } ] }, { "uniprot_ac": "Q9VEJ4", "gene_name": "Dmel\\CG5823", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q9VEJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VEJ4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q9VEJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VEJ4" } ] } ] }, { "uniprot_ac": "Q9VFC4", "gene_name": "Kpc1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q9VFC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VFC4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q9VFC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VFC4" } ] } ] }, { "uniprot_ac": "Q9VHI7", "gene_name": "Iru", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q9VHI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VHI7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q9VHI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VHI7" } ] } ] }, { "uniprot_ac": "Q9VI55", "gene_name": "Ufl1", "activity": [ { "ec_number": "2.3.2.-", "activity": "", "evidence": [ { "id": "Q9VI55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VI55" } ] } ] }, { "uniprot_ac": "Q9VJ14", "gene_name": "mib2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q9VJ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJ14" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q9VJ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJ14" } ] } ] }, { "uniprot_ac": "Q9VN58", "gene_name": "ctrip", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q9VN58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VN58" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "Q9VN58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VN58" } ] } ] }, { "uniprot_ac": "Q9VP20", "gene_name": "Mkrn1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q9VP20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VP20" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q9VP20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VP20" } ] } ] }, { "uniprot_ac": "Q9VQ00", "gene_name": "Dmel\\CG5440", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q9VQ00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQ00" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q9VQ00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQ00" } ] } ] }, { "uniprot_ac": "Q9VQ67", "gene_name": "Dmel\\CG4238", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q9VQ67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQ67" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "Q9VQ67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VQ67" } ] } ] }, { "uniprot_ac": "Q9VR91", "gene_name": "HERC2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q9VR91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VR91" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "Q9VR91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VR91" } ] } ] }, { "uniprot_ac": "Q9VSF3", "gene_name": "UbcE2M", "activity": [ { "ec_number": "2.3.2.34", "activity": "[E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine + [E2 NEDD8-conjugating enzyme]-L-cysteine = [E1 NEDD8-activating enzyme]-L-cysteine + [E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine.", "evidence": [ { "id": "Q9VSF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSF3" } ] }, { "ec_number": "2.3.2.34", "activity": "", "evidence": [ { "id": "Q9VSF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSF3" } ] } ] }, { "uniprot_ac": "Q9VSK2", "gene_name": "Cbl", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q9VSK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSK2" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q9VSK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSK2" } ] } ] }, { "uniprot_ac": "Q9VSS9", "gene_name": "NM_140022.1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q9VSS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSS9" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "Q9VSS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VSS9" } ] } ] }, { "uniprot_ac": "Q9VTH1", "gene_name": "Ube3a", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q9VTH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTH1" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "Q9VTH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTH1" } ] } ] }, { "uniprot_ac": "Q9VTY6", "gene_name": "vih", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q9VTY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTY6" } ] }, { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q9VTY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTY6" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q9VTY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VTY6" } ] } ] }, { "uniprot_ac": "Q9VUV7", "gene_name": "elgi", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q9VUV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUV7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q9VUV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VUV7" } ] } ] }, { "uniprot_ac": "Q9VVI3", "gene_name": "Nedd4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q9VVI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVI3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "Q9VVI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVI3" } ] } ] }, { "uniprot_ac": "Q9VW09", "gene_name": "Ltn1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q9VW09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VW09" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q9VW09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VW09" } ] } ] }, { "uniprot_ac": "Q9VX25", "gene_name": "", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q9VX25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VX25" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q9VX25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VX25" } ] } ] }, { "uniprot_ac": "Q9VX91", "gene_name": "Ubr1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q9VX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VX91" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Q9VX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VX91" } ] } ] }, { "uniprot_ac": "Q9VXE8", "gene_name": "Ubc7", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "Q9VXE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXE8" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "Q9VXE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VXE8" } ] } ] }, { "uniprot_ac": "Q9VY98", "gene_name": "Mgrn1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Q9VY98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VY98" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": 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"MTYELPPIILKGKELIKYRHIKRKYPVSKDFLHSNWWNVERFIVYALSPRCVIRNYAWRRRRTRSVCIIRRVRILLFDPRLKRMIKRRLQNVRHWSKGLVNYYKKMGRIEEHEETEVYRVAEPLAAEELSKQMKQQLELLKTGKRSLSLIEETTAIAEVPPKKPKQFPDITEEARVINDSDDRLDAAPSKQAAERTPTKSPAQVAASEDVPTPATPSKEQSGQTSTCSSAEKTDKVEKVGGGSKFLDMLISKVRVKNFARENNMPAEPSAVTFCTSEDEGSADFVGFDESVHQPGMLLTPLVPNNCKTTEGNSAFVSESLDAYMREHHINDSDSQDDKDKLLEPMGHDGQVTSHSMPPPMDMPAVPEALQRLRTVAERRQYLQRCKNHKMGIINNEANVYRELQRKQRQRKVKIGAMQALQASDSQMPFTRQGWQAASYVATEHSKYYYQVIQVDGEMVRLPGAQGNNLKREKSPYLSRLSRKEQEELKCSEQCLDARIQQELKVIPTRVSPPRNPKILNQYPLPAIFRPCPLSKKPLQRPLDDDTAALLLAGGSMAVVSMPNVELDVMPQLGRPLDEIAKRYLQHILPHHDITREWAEFSVSTLQAPPATMKDAEEQASQTPAGRRKSFTFVIPYLNDRNHILVRRVVDRSEHLDRSFKEEPNKLQEFTFREMLPPQPDAEIVACAEMISDMINTVAISCSENSFISEDPDALDASSVPKSSDLCPAKEETGKDTDKSGAKPKNLPNKQKRLANELRRLNATIIDAAARKADANKPCSKDYCHLGCICASLAGTELPVRDHCGRAECVLDCRCLSAEESRVMRLEAADGRGISNEDAFNLRRKATARLAKMEKDFTSTLVLTDNETLLINESQGDKKRRCTKAPKRYEDFDDSIYDEEEKDVVSPTTRKQKKHAAAAAAAAAAAAAAAAASAKISAPALSEPCFVKDTDLAKLKHCFVGLRRLSNVENLATFCMTHQLYKCFCGGDSPDGKPVVIEKDQWNAPVTHFNPDLAVRAHYSFERPPEETSTKKKGKEKKPKHKLESKSSNDVADQKPQTQAVETLPLKTESKQEPPPANSLFKDESPLKRSNELNKIFNYFRSRPDVCRRAISIPKNSYQRLNQRRADRVRHQIAREESLKTNEMLKMRIQGAVVYYRKEIDRQRKRELSKKPVIEVRNESDASDASVRQKKIETPAEGPTPGKRIKLKADEPPAQEKKAHMLDIQVPRIAACYSLNTASVDVLAPDMAKEATTSAAATGSTHGSTDTNSANVCTFYNDVVKNMNTLVSKKMQDIDLALQRESKIIPSPNEEILCIIKWTNFLAAFESGFVFIWDVQMKTHNFLAATTTNLMPSVCGAIAVVNTKFAPDPQALPLMARMLMNSMRNEKTNRLAVVMQGRQSFWLVKGFLRHMQGNACTKPTPMTHPLLTKKINVLCSLLVKQRVRENEKKTLGDGSGAPYEVLAGDVSPQTSLLMKNRSRDLKRKSQADERLLPSGPSMTKSSKPSAGGYPIAASVATSTTSAFASSSGKSTPVCTAKTNSASTKNKSSATGIRSNIEFRKVNHNDVDELQIPELHQTDHRWVVLDIFDDFSHIFVPSFSDMISLTRIHSVMQVAEERQKVVKLQFFPNAPYDAFVTPSSKKKIYFGPLSLDMPPPVLVLLQSVDRKMMLREVYQREHSIPVQRHRRSMAFWVLQINGQVHFEIDTESTAKLAAQQKNAIGTPPGLNVLKIPSQLSVEIEKNQDEVPPVVVIDSDEEDDDGERQLVIDEQDDEQAETDVKQEVERTGFTIQTLPSSGALQITISDSAETSSHPAKDVNTCHFSGGFMPFIANVPAKFGETAPTTQFLTPQVQVTTSQSGPETLTSSSSSHLPASKSAYPKINESLQELFSSGVPPGGITITKVDSQEKTLPNETVQVVKNKKSIAITGIHKQVTKAASSTATVTAARAPVVKPQSTSVSKVAPPIRPGATTQPKTLVRLYPKPALAAGRKSLPANAKTPVATPRQSQPVACDKPPLVSGSTLPALVEPSARKSLPSKPLAAGEHLRPRQSLPAKVTANPPAAARPDAASTSAQNLTNVSKAQLAKEEICYGIMVAKDLPRFRAKVEGSDFMIKIPEHGVFRFKTFGLAASFLSRHVAKDPKLKQFLPAEWKFHPLEQFNKQVPSRSQQSPAAIVIED", "length": 2175, "header": "tr|Q9W198-1|Q9W198_DROME Isoform 1 of Over compensating males, isoform A OS=Drosophila melanogaster OX=7227 GN=ocm PE=4 SV=1 CANONICAL=Q9W198-1" }, "isoforms": [ { "isoform_ac": "Q9W198-1", "url": "https://www.uniprot.org/uniprotkb/Q9W198/entry#Q9W198-1", "sequence": { "sequence": "MTYELPPIILKGKELIKYRHIKRKYPVSKDFLHSNWWNVERFIVYALSPRCVIRNYAWRRRRTRSVCIIRRVRILLFDPRLKRMIKRRLQNVRHWSKGLVNYYKKMGRIEEHEETEVYRVAEPLAAEELSKQMKQQLELLKTGKRSLSLIEETTAIAEVPPKKPKQFPDITEEARVINDSDDRLDAAPSKQAAERTPTKSPAQVAASEDVPTPATPSKEQSGQTSTCSSAEKTDKVEKVGGGSKFLDMLISKVRVKNFARENNMPAEPSAVTFCTSEDEGSADFVGFDESVHQPGMLLTPLVPNNCKTTEGNSAFVSESLDAYMREHHINDSDSQDDKDKLLEPMGHDGQVTSHSMPPPMDMPAVPEALQRLRTVAERRQYLQRCKNHKMGIINNEANVYRELQRKQRQRKVKIGAMQALQASDSQMPFTRQGWQAASYVATEHSKYYYQVIQVDGEMVRLPGAQGNNLKREKSPYLSRLSRKEQEELKCSEQCLDARIQQELKVIPTRVSPPRNPKILNQYPLPAIFRPCPLSKKPLQRPLDDDTAALLLAGGSMAVVSMPNVELDVMPQLGRPLDEIAKRYLQHILPHHDITREWAEFSVSTLQAPPATMKDAEEQASQTPAGRRKSFTFVIPYLNDRNHILVRRVVDRSEHLDRSFKEEPNKLQEFTFREMLPPQPDAEIVACAEMISDMINTVAISCSENSFISEDPDALDASSVPKSSDLCPAKEETGKDTDKSGAKPKNLPNKQKRLANELRRLNATIIDAAARKADANKPCSKDYCHLGCICASLAGTELPVRDHCGRAECVLDCRCLSAEESRVMRLEAADGRGISNEDAFNLRRKATARLAKMEKDFTSTLVLTDNETLLINESQGDKKRRCTKAPKRYEDFDDSIYDEEEKDVVSPTTRKQKKHAAAAAAAAAAAAAAAAASAKISAPALSEPCFVKDTDLAKLKHCFVGLRRLSNVENLATFCMTHQLYKCFCGGDSPDGKPVVIEKDQWNAPVTHFNPDLAVRAHYSFERPPEETSTKKKGKEKKPKHKLESKSSNDVADQKPQTQAVETLPLKTESKQEPPPANSLFKDESPLKRSNELNKIFNYFRSRPDVCRRAISIPKNSYQRLNQRRADRVRHQIAREESLKTNEMLKMRIQGAVVYYRKEIDRQRKRELSKKPVIEVRNESDASDASVRQKKIETPAEGPTPGKRIKLKADEPPAQEKKAHMLDIQVPRIAACYSLNTASVDVLAPDMAKEATTSAAATGSTHGSTDTNSANVCTFYNDVVKNMNTLVSKKMQDIDLALQRESKIIPSPNEEILCIIKWTNFLAAFESGFVFIWDVQMKTHNFLAATTTNLMPSVCGAIAVVNTKFAPDPQALPLMARMLMNSMRNEKTNRLAVVMQGRQSFWLVKGFLRHMQGNACTKPTPMTHPLLTKKINVLCSLLVKQRVRENEKKTLGDGSGAPYEVLAGDVSPQTSLLMKNRSRDLKRKSQADERLLPSGPSMTKSSKPSAGGYPIAASVATSTTSAFASSSGKSTPVCTAKTNSASTKNKSSATGIRSNIEFRKVNHNDVDELQIPELHQTDHRWVVLDIFDDFSHIFVPSFSDMISLTRIHSVMQVAEERQKVVKLQFFPNAPYDAFVTPSSKKKIYFGPLSLDMPPPVLVLLQSVDRKMMLREVYQREHSIPVQRHRRSMAFWVLQINGQVHFEIDTESTAKLAAQQKNAIGTPPGLNVLKIPSQLSVEIEKNQDEVPPVVVIDSDEEDDDGERQLVIDEQDDEQAETDVKQEVERTGFTIQTLPSSGALQITISDSAETSSHPAKDVNTCHFSGGFMPFIANVPAKFGETAPTTQFLTPQVQVTTSQSGPETLTSSSSSHLPASKSAYPKINESLQELFSSGVPPGGITITKVDSQEKTLPNETVQVVKNKKSIAITGIHKQVTKAASSTATVTAARAPVVKPQSTSVSKVAPPIRPGATTQPKTLVRLYPKPALAAGRKSLPANAKTPVATPRQSQPVACDKPPLVSGSTLPALVEPSARKSLPSKPLAAGEHLRPRQSLPAKVTANPPAAARPDAASTSAQNLTNVSKAQLAKEEICYGIMVAKDLPRFRAKVEGSDFMIKIPEHGVFRFKTFGLAASFLSRHVAKDPKLKQFLPAEWKFHPLEQFNKQVPSRSQQSPAAIVIED", "length": 2175, "header": "tr|Q9W198-1|Q9W198_DROME Isoform 1 of Over compensating males, isoform A OS=Drosophila melanogaster OX=7227 GN=ocm PE=4 SV=1 CANONICAL=Q9W198-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1199, "start_aa": "Thr", "end_pos": 1199, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1199", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 212, "start_aa": "Thr", "end_pos": 212, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr212", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 215, "start_aa": "Thr", "end_pos": 215, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr215", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W198", "url": "https://www.uniprot.org/uniprotkb/Q9W198" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W198", "url": "https://www.uniprot.org/uniprotkb/Q9W198" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W198", "url": "https://www.uniprot.org/uniprotkb/Q9W198" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W198", "url": "https://www.uniprot.org/uniprotkb/Q9W198" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W198", "url": "https://www.uniprot.org/uniprotkb/Q9W198" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W198", "url": "https://www.uniprot.org/uniprotkb/Q9W198" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W198", "url": "https://www.uniprot.org/uniprotkb/Q9W198" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W198", "url": "https://www.uniprot.org/uniprotkb/Q9W198" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W198", "url": "https://www.uniprot.org/uniprotkb/Q9W198" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W198", "url": "https://www.uniprot.org/uniprotkb/Q9W198" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W198", "url": "https://www.uniprot.org/uniprotkb/Q9W198" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG3363", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3363", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JUM5-1", "protein_name": "T-box transcription factor 22", "gene_name": "Tbx22", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTKIPPAASSLPGMALSSRAHAFSVEALMGRPSKRKAQDPREEMQPELQEEQFIEEGEEILSSPSGDSEQPAEKRPKAESSKTVFSCSDNESNSLESLLEESIIQVELQGSDLWKRFHDIGTEMIITKAGRRMFPSVRIKVKGMDPVKQYYVILDVVPVDSKRYRYVYHSSQWMVAGNTDHSCITPRFYVHPDSPCSGENWMRQIISFDRVKLTNNEMDDKGHIILQSMHKYKPRVHVVEEDSRIDLSLIQSFPTEGVKTFSFKETEFTTVTAYQNQQITKLKIDRNPFAKGFRDPGRNRGVLDGFLETYPWRPSFTMDFKPFVPDTQNGSSGSSPVTSSGGAPSPLNSLLSPSCSPPTVYIPPSSIGMTHPETYLHNVNVPFCYRICPTNYWRPQPFVLPTPERLPSFNSSQSFPPLMMEVPLVSSRGFINSNSGLHEDCNGHCLQASHSTSQMLYGLQNPGNIFHPNPIAQEAICCPFHPPNGCYRYNVSMPPRLENVANHLSENGTNQISFTGGSCDHSHWYPAINHYF", "length": 533 }, "evidence": [ { "id": "HGNC:11600", "url": "https://alliancegenome.org/gene/HGNC:11600#orthology", "database": "AGR" }, { "id": "MGI:2389465", "url": "https://alliancegenome.org/gene/MGI:2389465#orthology", "database": "AGR" }, { "id": "RGD:1589764", "url": "https://alliancegenome.org/gene/RGD:1589764#orthology", "database": "AGR" }, { "id": "FB:FBgn0266083", "url": "https://alliancegenome.org/gene/FB:FBgn0266083#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A2R8Q7R4-1", "protein_name": "T-box transcription factor TBX22 isoform X1", "gene_name": "tbx22", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MQSITRQVDHTSGNRCKKMKVENRENESLQDVLEYDSDTLRRTLFDAQDLRKSAKERKPAGAEAVRKVRVDLQGSDLWKRFYEIGTEMIITKVGRRMFPSIRVKVHNLDPLQQYSIAMDIMPMDSKKYRYVYHSSQWVIAGNTDHSCIPPHLYVHPDSPCSGENWMRQVISFDRVKLTNNELDDRGHIILKSMHKYRPRIHVILHCPPECLSKRLLSLPADGVFTFSFPETQFTTVTAYQNQQITKLKIDRNPFAKGFRERNGAVLDGILESYSWHSPFNGFKSLAMELQGRCFGSSASGITPSVSSAQAVHPTAFSSPQCCKILPSSCFLAYRAYCSICLNNYTGLRPMLDLPLLTSLPVKKGDRCRSHWLYNSAGTSMHPIHNTLSGWASENENTASAFMSPHSYSFPISHRFSTDTHHLKLAHSESTVLQMPMISSIGYSP", "length": 444 }, "evidence": [ { "id": "HGNC:11600", "url": "https://alliancegenome.org/gene/HGNC:11600#orthology", "database": "AGR" }, { "id": "MGI:2389465", "url": "https://alliancegenome.org/gene/MGI:2389465#orthology", "database": "AGR" }, { "id": "RGD:1589764", "url": "https://alliancegenome.org/gene/RGD:1589764#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A2R8QEJ0-1", "protein_name": "T-box transcription factor TBX15", "gene_name": "tbx15", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDRRRSAAALSSRAHAFSVEALIGTNKKRKLRGWEEKELELSMESLASNGQLGDGEDPANCLDIDPDSEASPGSDGEGLAERTSCSFGSPADLTSAACDPSPSASMEEIQVELQCADLWKRFHDIGTEMIITKAGRRMFPAMRVKIVGLDPHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSLASGDTWMRQVVSFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDFSSELSPTKPVPTGEGVKTFSFPETVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRTGLEAIMETYAFWRPPVRTLTFEDFTNMQKQQGGSTGTSPTTSSTGTPSPSGATHLLSPSCSPPTFHLAPNTFNVGCRESQLCNLGLSEYPACARSNMAALQGYGGLADGSYGRLQTTGGAVASAQASESFLPQRTSSLIAAGMQGGAHGSLATGNSGSGSGGGKMDAYGSQLASFPASQLQYVMQAGASSASGSSASSGSSSSSAHMFSGSHHHVQQSTYNAFSLHNPYNLYGYNFPASPRLAASPEKPQGGLLCSSSSAGAFAERQYLSNGGMDSMHMIGNPTGSQQGAGSCDGRQYGSSSQMSMHMV", "length": 616 }, "evidence": [ { "id": "HGNC:11594", "url": "https://alliancegenome.org/gene/HGNC:11594#orthology", "database": "AGR" }, { "id": "MGI:1277234", "url": "https://alliancegenome.org/gene/MGI:1277234#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZJ07-1", "protein_name": "T-box transcription factor 15", "gene_name": "Tbx15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSERRRSAVALSSRAHAFSVEALIGSNKKRKLRDWEEKGLDLSMEALSPTGPLGDTDDPATHGLEPHPDSEQSTGSDSEVLTERTSCSFSAHTDLASGAAGSVPVAMSSMEEIQVELQCADLWKRFHDIGTEMIITKAGRRMFPAMRVKITGLDPHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSLASGDTWMRQVVSFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDFSSDLSPTKPVPVGDGVKTFNFPETVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRTGLEAIMETYAFWRPPVRTLTFEDFTTMQKQQGGSTGTSPSTSSTGTPSPSASSHLLSPSCSPPTFHLAPNTFNVGCRESQLCNLNLSDYPPCARSNMAALQSYPGLSDSGYNRLQSGTASATQPSETFMPQRTPSLISGIPTPPSLPSNSKMEAYGGQLGSFPTSQFQYVMQAGNAASSSSSPHMFGGSHMQQSSYNAFSLHNPYNLYGYNFPTSPRLAASPEKLSASQSTLLCSSPSNGAFGERQYLPTGMEHSVHMISPSTNNQQATNTCDGRQYGAVPGSSSQMSVHMV", "length": 602 }, "evidence": [ { "id": "HGNC:11594", "url": "https://alliancegenome.org/gene/HGNC:11594#orthology", "database": "AGR" }, { "id": "MGI:1277234", "url": "https://alliancegenome.org/gene/MGI:1277234#orthology", "database": "AGR" }, { "id": "RGD:1308094", "url": "https://alliancegenome.org/gene/RGD:1308094#orthology", "database": "AGR" }, { "id": "FB:FBgn0266083", "url": "https://alliancegenome.org/gene/FB:FBgn0266083#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O70306-1", "protein_name": "T-box transcription factor TBX15", "gene_name": "Tbx15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSERRRSAVALSSRAHAFSVEALIGSNKKRKLRDWEEKGLDLSMEALSPAGPLGDTDDPATHGLEPHPDSEQSTGSDSEVLTERTSCSFSTHTDLASGAAGPVPAAMSSMEEIQVELQCADLWKRFHDIGTEMIITKAGRRMFPAMRVKITGLDPHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSLASGDTWMRQVVSFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDFSSDLSPTKPVPVGDGVKTFNFPETVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRTGLEAIMETYAFWRPPVRTLTFEDFTTMQKQQGGSTGTSPTTSSTGTPSPSASSHLLSPSCSPPTFHLAPNTFNVGCRESQLCNLNLSDYPPCARSNMAALQSYPGLSDSGYNRLQSGTASATQPSETFMPQRTPSLISGIPTPPSLPSNSKMEAYGGQLGSFPTSQFQYVMQAGNAASSSSSPHMFGGSHMQQSSYNAFSLHNPYNLYGYNFPTSPRLAASPEKLSASQSTLLCSSPSNGAFGERQYLPTGMEHSMHMISPSTNNQQATNTCDGRQYGAVPGSASQMSVHMV", "length": 602 }, "evidence": [ { "id": "HGNC:11594", "url": "https://alliancegenome.org/gene/HGNC:11594#orthology", "database": "AGR" }, { "id": "MGI:1277234", "url": "https://alliancegenome.org/gene/MGI:1277234#orthology", "database": "AGR" }, { "id": "RGD:1308094", "url": "https://alliancegenome.org/gene/RGD:1308094#orthology", "database": "AGR" }, { "id": "FB:FBgn0266083", "url": "https://alliancegenome.org/gene/FB:FBgn0266083#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8K402-1", "protein_name": "T-box transcription factor TBX22", "gene_name": "Tbx22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALSSRAHAFSVEALMGRPSKRKAQDPREEMQPELQEEQFVEEGEEILRSPSRDSQQPEKRLKAESSKTVFSCSDESNSQESLQEESVIQVELQGSDLWKRFHDIGTEMIITKAGRRMFPSVRIKVKGMDPVKQYYVILDVVPVDSKRYRYVYHSSQWMVAGNTDHSCITPRFYVHPDSPCSGENWMRQIISFDRVKLTNNEMDDKGHIILQSMHKYNPRVHVVEQDSRIDLSLIESFPTEGVKTFSFKETEFTTVTAYQNQQITKLKIDRNPFAKGFRDPGRNRGVLDGFLETYPWMPSFSMDFKTFVTDTQSGSSGSSPVTSSGGAPSPLNSLLSPSCSPPMVYIPPSSFGMTYPDAYLHSVNIPFCYRICPTNNWRSQPFVLPTPERLPSFIIPQTLPPLMMEVPVVSSRGIINPNSGLHEDCNGQCLQASHSANQMLYGLQNPGNIFHPNAIAQEAISYPFHPPNGCYRYTISMPPRLENVASHLSENGTSQISFTEGSCDHSHWYPAINHYL", "length": 517 }, "evidence": [ { "id": "HGNC:11600", "url": "https://alliancegenome.org/gene/HGNC:11600#orthology", "database": "AGR" }, { "id": "MGI:2389465", "url": "https://alliancegenome.org/gene/MGI:2389465#orthology", "database": "AGR" }, { "id": "RGD:1589764", "url": "https://alliancegenome.org/gene/RGD:1589764#orthology", "database": "AGR" }, { "id": "FB:FBgn0266083", "url": "https://alliancegenome.org/gene/FB:FBgn0266083#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96SF7-1", "protein_name": "T-box transcription factor TBX15", "gene_name": "TBX15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSERRRSAVALSSRAHAFSVEALIGSNKKRKLRDWEEKGLDLSMEALSPAGPLGDTEDAAAHGLEPHPDSEQSTGSDSEVLTERTSCSFSTHTDLASGAAGPVPAAMSSMEEIQVELQCADLWKRFHDIGTEMIITKAGRRMFPAMRVKITGLDPHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSLASGDTWMRQVVSFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDFSSDLSPTKPVPVGDGVKTFNFPETVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRTGLEAIMETYAFWRPPVRTLTFEDFTTMQKQQGGSTGTSPTTSSTGTPSPSASSHLLSPSCSPPTFHLAPNTFNVGCRESQLCNLNLSDYPPCARSNMAALQSYPGLSDSGYNRLQSGTTSATQPSETFMPQRTPSLISGIPTPPSLPGNSKMEAYGGQLGSFPTSQFQYVMQAGNAASSSSSPHMFGGSHMQQSSYNAFSLHNPYNLYGYNFPTSPRLAASPEKLSASQSTLLCSSPSNGAFGERQYLPSGMEHSMHMISPSPNNQQATNTCDGRQYGAVPGSSSQMSVHMV", "length": 602 }, "evidence": [ { "id": "HGNC:11594", "url": "https://alliancegenome.org/gene/HGNC:11594#orthology", "database": "AGR" }, { "id": "MGI:1277234", "url": "https://alliancegenome.org/gene/MGI:1277234#orthology", "database": "AGR" }, { "id": "RGD:1308094", "url": "https://alliancegenome.org/gene/RGD:1308094#orthology", "database": "AGR" }, { "id": "FB:FBgn0266083", "url": "https://alliancegenome.org/gene/FB:FBgn0266083#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Y458-1", "protein_name": "T-box transcription factor TBX22", "gene_name": "TBX22", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALSSRARAFSVEALVGRPSKRKLQDPIQAEQPELREKKGGEEEEERRSSAAGKSEPLEKQPKTEPSTSASSGCGSDSGYGNSSESLEEKDIQMELQGSELWKRFHDIGTEMIITKAGRRMFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHLCIIPRFYVHPDSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSMHKYKPRVHVIEQGSSVDLSQIQSLPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGFRDTGRNRGVLDGLLETYPWRPSFTLDFKTFGADTQSGSSGSSPVTSSGGAPSPLNSLLSPLCFSPMFHLPTSSLGMPCPEAYLPNVNLPLCYKICPTNFWQQQPLVLPAPERLASSNSSQSLAPLMMEVPMLSSLGVTNSKSGSSEDSSDQYLQAPNSTNQMLYGLQSPGNIFLPNSITPEALSCSFHPSYDFYRYNFSMPSRLISGSNHLKVNDDSQVSFGEGKCNHVHWYPAINHYL", "length": 520 }, "evidence": [ { "id": "HGNC:11600", "url": "https://alliancegenome.org/gene/HGNC:11600#orthology", "database": "AGR" }, { "id": "MGI:2389465", "url": "https://alliancegenome.org/gene/MGI:2389465#orthology", "database": "AGR" }, { "id": "RGD:1589764", "url": "https://alliancegenome.org/gene/RGD:1589764#orthology", "database": "AGR" }, { "id": "FB:FBgn0266083", "url": "https://alliancegenome.org/gene/FB:FBgn0266083#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell fate specification", "id": "GO:0001708", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001708", "evidence": [ { "database": "UniProtKB", "id": "Q9W198", "url": "https://www.uniprot.org/uniprotkb/Q9W198" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q9W198", "url": "https://www.uniprot.org/uniprotkb/Q9W198" } ], "pmid": "" }, { "name": "dosage compensation by hyperactivation of X chromosome", "id": "GO:0009047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009047", "evidence": [ { "database": "UniProtKB", "id": "Q9W198", "url": "https://www.uniprot.org/uniprotkb/Q9W198" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9W198", "url": "https://www.uniprot.org/uniprotkb/Q9W198" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "Q9W198", "url": "https://www.uniprot.org/uniprotkb/Q9W198" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "Q9W198", "url": "https://www.uniprot.org/uniprotkb/Q9W198" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q9W198", "url": "https://www.uniprot.org/uniprotkb/Q9W198" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1177, "end_pos": 1179, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1475, "end_pos": 1477, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1544, "end_pos": 1546, "annotation": "n_glycosylation_sequon" }, { "start_pos": 178, "end_pos": 180, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1880, "end_pos": 1882, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1910, "end_pos": 1912, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2072, "end_pos": 2074, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2075, "end_pos": 2077, "annotation": "n_glycosylation_sequon" }, { "start_pos": 330, "end_pos": 332, "annotation": "n_glycosylation_sequon" }, { "start_pos": 761, "end_pos": 763, "annotation": "n_glycosylation_sequon" }, { "start_pos": 865, "end_pos": 867, "annotation": "n_glycosylation_sequon" }, { "start_pos": 871, "end_pos": 873, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9W198", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W198" }, { "id": "PF16059", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16059" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MGA conserved", "eco_id": "ECO_0000259", "start_pos": 771, "end_pos": 821, "start_aa": "Lys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 212, 215, 1199 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1177, "end_pos": 1179 }, { "start_pos": 1475, "end_pos": 1477 }, { "start_pos": 1544, "end_pos": 1546 }, { "start_pos": 178, "end_pos": 180 }, { "start_pos": 1880, "end_pos": 1882 }, { "start_pos": 1910, "end_pos": 1912 }, { "start_pos": 2072, "end_pos": 2074 }, { "start_pos": 2075, "end_pos": 2077 }, { "start_pos": 330, "end_pos": 332 }, { "start_pos": 761, "end_pos": 763 }, { "start_pos": 865, "end_pos": 867 }, { "start_pos": 871, "end_pos": 873 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { 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"MCDFDALWADVLRIFPVLGGANAVSNDPVEENVFQNVRQHLMVLGSIDTFAAVVDLEIQSTIRNVLVPKFWKHIHDGLVSSKLQGWINDQALAIEALPDKNGLFTQFIDAINELHDSFQSLMQVKPRLIQLVGAETKPTAKTVKLMQEEGIKNCLRDCLLAQLPPNFSVVVGAFYWVHFKLFTKASNLALTTVDSDVFDELLCVGCNFEAEQCCCQRLTDMVNKTNMKLFEMNLIDRLTGSALTALIKLKIKEHISDTCMGIFDRSHLKQLETWLSDVIMSWLTNIFTEWKSKDSISDIEVPESVKSFKVKLTYFMYETFAQSVIGQFFSIIIDYPDSIPAIDDLKICMEKIDMRVYLTESLRNSLEARILHPGVNTMDILTGYVAAIKAIRHLDSTGVILEMVTAPIKDYLRKRNDTVRRVVTGLTEEGPTDLSEELAKGETIKECKDSGTDEFSNWENWQPDPFGIDASIMQYNSSRKMRSADIISMVVDIYGSKELFMTEYRNLMADRLLAQLDFNSEKEIRNLELLKIRFGESLLHSCEVMLKDVTDSKRINAHIHSDGDRTENQLFDISSLIVSAQFWPSFNKESLQLPEEIENEFKKYTKAYEAYKGNRTLNWRTVTGRVNIEIEIGDRTMEMVVSPILAVIIYHFQTKNEWTIEDLSSITKVPASALRRRLSFWQNHGLISETTPGIFTLLEKESEKSQYEDMSLAEADEEDLESAMASASDQREEELQVFWSYIVGMLTNLDSMPIDRIHQMLKLFASHSGGVEFTQDELKHFLQRKVREHKLIFSGGVYQLAK", "length": 802, "header": "tr|Q9W1E5-1|Q9W1E5_DROME Isoform 1 of Anaphase-promoting complex subunit 2 OS=Drosophila melanogaster OX=7227 GN=mr PE=1 SV=1 CANONICAL=Q9W1E5-1" }, "isoforms": [ { "isoform_ac": "Q9W1E5-1", "url": "https://www.uniprot.org/uniprotkb/Q9W1E5/entry#Q9W1E5-1", "sequence": { "sequence": "MCDFDALWADVLRIFPVLGGANAVSNDPVEENVFQNVRQHLMVLGSIDTFAAVVDLEIQSTIRNVLVPKFWKHIHDGLVSSKLQGWINDQALAIEALPDKNGLFTQFIDAINELHDSFQSLMQVKPRLIQLVGAETKPTAKTVKLMQEEGIKNCLRDCLLAQLPPNFSVVVGAFYWVHFKLFTKASNLALTTVDSDVFDELLCVGCNFEAEQCCCQRLTDMVNKTNMKLFEMNLIDRLTGSALTALIKLKIKEHISDTCMGIFDRSHLKQLETWLSDVIMSWLTNIFTEWKSKDSISDIEVPESVKSFKVKLTYFMYETFAQSVIGQFFSIIIDYPDSIPAIDDLKICMEKIDMRVYLTESLRNSLEARILHPGVNTMDILTGYVAAIKAIRHLDSTGVILEMVTAPIKDYLRKRNDTVRRVVTGLTEEGPTDLSEELAKGETIKECKDSGTDEFSNWENWQPDPFGIDASIMQYNSSRKMRSADIISMVVDIYGSKELFMTEYRNLMADRLLAQLDFNSEKEIRNLELLKIRFGESLLHSCEVMLKDVTDSKRINAHIHSDGDRTENQLFDISSLIVSAQFWPSFNKESLQLPEEIENEFKKYTKAYEAYKGNRTLNWRTVTGRVNIEIEIGDRTMEMVVSPILAVIIYHFQTKNEWTIEDLSSITKVPASALRRRLSFWQNHGLISETTPGIFTLLEKESEKSQYEDMSLAEADEEDLESAMASASDQREEELQVFWSYIVGMLTNLDSMPIDRIHQMLKLFASHSGGVEFTQDELKHFLQRKVREHKLIFSGGVYQLAK", "length": 802, "header": "tr|Q9W1E5-1|Q9W1E5_DROME Isoform 1 of Anaphase-promoting complex subunit 2 OS=Drosophila melanogaster OX=7227 GN=mr PE=1 SV=1 CANONICAL=Q9W1E5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W1E5", "url": "https://www.uniprot.org/uniprotkb/Q9W1E5" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W1E5", "url": "https://www.uniprot.org/uniprotkb/Q9W1E5" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1E5", "url": "https://www.uniprot.org/uniprotkb/Q9W1E5" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1E5", "url": "https://www.uniprot.org/uniprotkb/Q9W1E5" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W1E5", "url": "https://www.uniprot.org/uniprotkb/Q9W1E5" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W1E5", "url": "https://www.uniprot.org/uniprotkb/Q9W1E5" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W1E5", "url": "https://www.uniprot.org/uniprotkb/Q9W1E5" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1E5", "url": "https://www.uniprot.org/uniprotkb/Q9W1E5" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1E5", "url": "https://www.uniprot.org/uniprotkb/Q9W1E5" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W1E5", "url": "https://www.uniprot.org/uniprotkb/Q9W1E5" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W1E5", "url": "https://www.uniprot.org/uniprotkb/Q9W1E5" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG3060", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3060", "resource": "KEGG Pathway" }, { "id": "R-DME-141430", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-141430", "resource": "Reactome", "description": "Inactivation of APC/C via direct inhibition of the APC/C complex" }, { "id": "R-DME-174048", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-174048", "resource": "Reactome", "description": "APC/C:Cdc20 mediated degradation of Cyclin B" }, { "id": "R-DME-174084", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-174084", "resource": "Reactome", "description": "Autodegradation of Cdh1 by Cdh1:APC/C" }, { "id": "R-DME-174154", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-174154", "resource": "Reactome", "description": "APC/C:Cdc20 mediated degradation of Securin" }, { "id": "R-DME-174178", "name": "", "url": 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"Q9W1E5", "url": "https://www.uniprot.org/uniprotkb/Q9W1E5" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "Q9W1E5", "url": "https://www.uniprot.org/uniprotkb/Q9W1E5" } ], "pmid": "" }, { "name": "metaphase/anaphase transition of mitotic cell cycle", "id": "GO:0007091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007091", "evidence": [ { "database": "UniProtKB", "id": "Q9W1E5", "url": "https://www.uniprot.org/uniprotkb/Q9W1E5" } ], "pmid": "" }, { "name": "negative regulation of synaptic assembly at neuromuscular junction", "id": "GO:0045886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045886", "evidence": [ { "database": "UniProtKB", "id": "Q9W1E5", "url": "https://www.uniprot.org/uniprotkb/Q9W1E5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "anaphase-promoting complex", "id": "GO:0005680", "url": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W1E9" } ] }, { "name": "Fmo-1", "type": "synonym", "evidence": [ { "id": "NP_611859", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611859" }, { "id": "Q9W1E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W1E9" } ] } ], "protein_names": [ { "name": "Flavin-containing monooxygenase", "type": "recommended", "evidence": [ { "id": "Q9W1E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W1E9/entry#names_and_taxonomy" } ] }, { "name": "1.-.-.-", "type": "synonym", "evidence": [ { "id": "Q9W1E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W1E9/entry#names_and_taxonomy" } ] }, { "name": "CG3006-PA", "type": "synonym", "evidence": [ { "id": "NP_611859", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611859" } ] }, { "name": "Flavin-containing monooxygenase 1", "type": "synonym", "evidence": [ { "id": "NP_611859", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611859" } ] }, { "name": "Fmo-1-PA", "type": "synonym", "evidence": [ { "id": "NP_611859", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611859" } ] } ], "function": [], "disease": [ { "disease_id": "DOID:0080361", "recommended_name": { "id": "DOID:0080361", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080361", "name": "trimethylaminuria", "description": "An inherited metabolic disorder characterized by the inability to break down trimethylamine and has_material_basis_in homozygous or compound heterozygous mutation in the gene encoding flavin-containing monooxygenase-3 on chromosome 1q24." }, "synonyms": [ { "id": "DOID:0080361", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080361", "name": "fish-odor syndrome", "description": "" }, { "id": "MONDO:0018767", "resource": "MONDO", "url": 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"MONDO:0018767", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018767", "name": "fish odour syndrome", "description": "" }, { "id": "MONDO:0018767", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018767", "name": "stale fish syndrome", "description": "" }, { "id": "MIM:602079", "resource": "MIM", "url": "https://www.omim.org/entry/602079", "name": "Trimethylaminuria", "description": "Trimethylaminuria" } ], "unlinked_id_list": [], "evidence": [ { "id": "0080361", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080361" } ] }, { "disease_id": "DOID:10763", "recommended_name": { "id": "DOID:10763", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries." }, "synonyms": [ { "id": "DOID:10763", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10763", "name": "HTN", "description": "" }, { "id": "DOID:10763", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10763", "name": "hyperpiesia", "description": "" }, { "id": "DOID:10763", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10763", "name": "vascular hypertensive disorder", "description": "" } ], "unlinked_id_list": [ "DOID:13731", "DOID:11130" ], "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ] }, { "disease_id": "DOID:655", "recommended_name": { "id": "DOID:655", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:655", "name": "inherited metabolic disorder", "description": "A disease of metabolism that is characterized by enzyme deficiency or accumulation of enzymes or toxins which interfere with normal function due to inherited enzyme abnormality." }, "synonyms": [ { "id": "DOID:655", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:655", "name": "Inborn Errors of Metabolism", "description": "" }, { "id": "DOID:655", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:655", "name": "Metabolic hereditary disorder", "description": "" }, { "id": "DOID:655", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:655", "name": "inborn metabolism disorder", "description": "" } ], "unlinked_id_list": [ "DOID:0080541", "DOID:0050832", "DOID:0060333", "DOID:0060176", "DOID:0111368", "DOID:0050674", "DOID:9265", "DOID:2345", "DOID:0050728", "DOID:0060159", "DOID:857", "DOID:0111034", "DOID:0112100", "DOID:0081132", "DOID:0111417", "DOID:9267", "DOID:0050721", "DOID:0081329", "DOID:0050594", "DOID:0112317", "DOID:0110003", "DOID:0081377", "DOID:2368" ], "evidence": [ { "id": "655", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:655" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W1E9", "url": "https://www.uniprot.org/uniprotkb/Q9W1E9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Fmo1", "url": "https://www.uniprot.org/uniprotkb/Q9W1E9", "locus": {} } ], "crossref": [ { "id": "FB:FBgn0034943", "url": "https://alliancegenome.org/gene/FB:FBgn0034943", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0034943", "url": "https://bgee.org/?page=gene&gene_id=FBgn0034943", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0034943", "url": "https://flybase.org/reports/FBgn0034943", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "37814", "url": "https://www.ncbi.nlm.nih.gov/gene/37814", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000960", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000960", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020946", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020946", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036188", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036188", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050346", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050346", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG3006", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3006", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MVTPLWK", "url": "https://omabrowser.org/oma/group/MVTPLWK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W1E9", "url": "https://www.orthodb.org/?gene=Q9W1E9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23023", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23023", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00743", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00743", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_611859", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611859", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W1E9", "url": "https://www.uniprot.org/uniprotkb/Q9W1E9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W1E9-1", "url": "https://www.uniprot.org/uniprotkb/Q9W1E9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMSVCIIGAGTAGLCCARHSIANGFETTVFELSDRIGGTWVYNEATGAVNGIDVHSSMYKNLRTNLPKEVMGFPDFEIGANEASYVRSDEICDFLNQYANHFDLKKHIKFDSYVIRVLQRKTKWQVLFKDLVTNKIEFQYFDKVLVANGHYHTPNYSQIPNMERFKGQFLHSHDFRSREVFEGKSVLVIGAGPSGMDLSNIISRTADRVTISHHLTDIGQHSFFENVQQKPDVRELDEKGAFFVDGSYQEFDTVFFCTGYKYAFPFLTVDSGIYVEDNYVQELYKQCINIRNPSMALIGLPFYVCAAQMMDIQARFIMSYYNGSNELPSTEDMLKDTRDRMGKLWAEGLRKRHAHMLGPKQIDYFTDLSQTAGVKNIKPVMTKLHNESSKCFNENLLHFREDNFAILDDETFIKLN", "length": 416, "header": "tr|Q9W1E9-1|Q9W1E9_DROME Isoform 1 of Flavin-containing monooxygenase OS=Drosophila melanogaster OX=7227 GN=Fmo1 PE=3 SV=1 CANONICAL=Q9W1E9-1" }, "isoforms": [ { "isoform_ac": "Q9W1E9-1", "url": "https://www.uniprot.org/uniprotkb/Q9W1E9/entry#Q9W1E9-1", "sequence": { "sequence": "MMSVCIIGAGTAGLCCARHSIANGFETTVFELSDRIGGTWVYNEATGAVNGIDVHSSMYKNLRTNLPKEVMGFPDFEIGANEASYVRSDEICDFLNQYANHFDLKKHIKFDSYVIRVLQRKTKWQVLFKDLVTNKIEFQYFDKVLVANGHYHTPNYSQIPNMERFKGQFLHSHDFRSREVFEGKSVLVIGAGPSGMDLSNIISRTADRVTISHHLTDIGQHSFFENVQQKPDVRELDEKGAFFVDGSYQEFDTVFFCTGYKYAFPFLTVDSGIYVEDNYVQELYKQCINIRNPSMALIGLPFYVCAAQMMDIQARFIMSYYNGSNELPSTEDMLKDTRDRMGKLWAEGLRKRHAHMLGPKQIDYFTDLSQTAGVKNIKPVMTKLHNESSKCFNENLLHFREDNFAILDDETFIKLN", "length": 416, "header": "tr|Q9W1E9-1|Q9W1E9_DROME Isoform 1 of Flavin-containing monooxygenase OS=Drosophila melanogaster OX=7227 GN=Fmo1 PE=3 SV=1 CANONICAL=Q9W1E9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W1E9", "url": "https://www.uniprot.org/uniprotkb/Q9W1E9" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W1E9", "url": "https://www.uniprot.org/uniprotkb/Q9W1E9" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1E9", "url": "https://www.uniprot.org/uniprotkb/Q9W1E9" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1E9", "url": "https://www.uniprot.org/uniprotkb/Q9W1E9" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W1E9", "url": "https://www.uniprot.org/uniprotkb/Q9W1E9" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W1E9", "url": "https://www.uniprot.org/uniprotkb/Q9W1E9" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W1E9", "url": "https://www.uniprot.org/uniprotkb/Q9W1E9" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1E9", "url": "https://www.uniprot.org/uniprotkb/Q9W1E9" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1E9", "url": "https://www.uniprot.org/uniprotkb/Q9W1E9" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W1E9", "url": "https://www.uniprot.org/uniprotkb/Q9W1E9" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W1E9", "url": "https://www.uniprot.org/uniprotkb/Q9W1E9" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG3006", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3006", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AA53ECJ5-1", "protein_name": "Flavin-containing monooxygenase", "gene_name": "si:dkey-239i20.4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVKRVAVIGAGSSGLAAIKCCLDEGLEPVCFESSDDIGGLWRFREKPETDRCSIYHSLTVNTSKEMMCYSDFPVPDNFPNFMHNSLIVQYYRLYAEHFNLFEHIHFQTTVRSVRQRPDFSVSGQWEVVTADRDGQVETHMFDGVLVCVGHYTQPIKPLSEFPGIDTFPGTVIHSWEYKKPDQYIGKKVLIIGIGNSGGDIAVELSRTCEKTFLSTRKGSWVIGRMVEKGLPLDMMNISRVQDLMHCLIPRALVNWIGERSLNQRHDHKLYGLQPKHRILDHRPVINDDLPGRILVGELVLKPNVQTFHGSTVVFDDGSIEEKIDAVILCTGYDYKFPFLPDSLNSSADGGMKLYRRIFPPSLERPTLAIIGLLQTRGPIMPAAELQARWATRVIKGLNHLPSAEKMSKRIEKDIKPYLKSHPCPKLASLQVDYIPYLDSIAKEVGACPNIAWLLMTDPALGLRVFLGPCTPYQFRLSGPGHWKGARQAILTQWERVAKPMKTRPIPEPSSFSLLFWLGLSGGGAVILAIIALQKKIPLFMGIS", "length": 543 }, "evidence": [ { "id": "MGI:3643320", "url": "https://alliancegenome.org/gene/MGI:3643320#orthology", "database": "AGR" }, { "id": "MGI:1310002", "url": "https://alliancegenome.org/gene/MGI:1310002#orthology", "database": "AGR" }, { "id": "MGI:2681841", "url": "https://alliancegenome.org/gene/MGI:2681841#orthology", "database": "AGR" }, { "id": "MGI:2429497", "url": "https://alliancegenome.org/gene/MGI:2429497#orthology", "database": "AGR" }, { "id": "MGI:1100496", "url": "https://alliancegenome.org/gene/MGI:1100496#orthology", "database": "AGR" }, { "id": "MGI:1916776", "url": "https://alliancegenome.org/gene/MGI:1916776#orthology", "database": "AGR" }, { "id": "HGNC:3769", "url": "https://alliancegenome.org/gene/HGNC:3769#orthology", "database": "AGR" }, { "id": "HGNC:3771", "url": "https://alliancegenome.org/gene/HGNC:3771#orthology", "database": "AGR" }, { "id": "HGNC:3772", "url": "https://alliancegenome.org/gene/HGNC:3772#orthology", "database": "AGR" }, { "id": "HGNC:3770", "url": "https://alliancegenome.org/gene/HGNC:3770#orthology", "database": "AGR" }, { "id": "HGNC:24024", "url": "https://alliancegenome.org/gene/HGNC:24024#orthology", "database": "AGR" }, { "id": "RGD:1595083", "url": "https://alliancegenome.org/gene/RGD:1595083#orthology", "database": "AGR" }, { "id": "RGD:628601", "url": "https://alliancegenome.org/gene/RGD:628601#orthology", "database": "AGR" }, { "id": "RGD:1559491", "url": "https://alliancegenome.org/gene/RGD:1559491#orthology", "database": "AGR" }, { "id": "RGD:628600", "url": "https://alliancegenome.org/gene/RGD:628600#orthology", "database": "AGR" }, { "id": "RGD:619761", "url": "https://alliancegenome.org/gene/RGD:619761#orthology", "database": "AGR" }, { "id": "RGD:2622", "url": "https://alliancegenome.org/gene/RGD:2622#orthology", "database": "AGR" }, { "id": "RGD:1595097", "url": "https://alliancegenome.org/gene/RGD:1595097#orthology", "database": "AGR" }, { "id": "RGD:1559819", "url": "https://alliancegenome.org/gene/RGD:1559819#orthology", "database": "AGR" }, { "id": "SGD:S000001219", "url": "https://alliancegenome.org/gene/SGD:S000001219#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZBP5-1", "protein_name": "Flavin-containing monooxygenase", "gene_name": "Fmol", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGVKKVAVIGAGVSGLGAIKCCLDEGLEPTCFEKRSDIGGLWKYEEISKSGNLGIYKSLTCNTSKEMTAFSDYPIPDHYPNYMHNSKMMEYLRMYARHFGLLKHIQFQTKVCSIKKRPDFSSSGQWDVVVETGETQKTYIFDGIMVCSGHYTEKHFPLQDFEGISKFQGSCLHSWEYKHPNSFSGKRVVVIGIGNSGADVAGEISRVADQVFLSTRRGAWVWSRVWDHGNPMDASLFTRYNRAVQKFCPRYLINRQMEKKLNARFNHANFGLLPQHRILDHRTVFSDDLPSHIITGKVKIKTNVKTFTSTSAVFEDGTEENIDVVIFATGYKLAFPFLSDDSGILDSQYSMFKYVFPPELEKPTLAFIGIVQPAGAIIPTSELQSRWVVRVFTGLQKLPPKKAMMADIYRKHQADKDAIKNLKDSSRRVQFIDYMDEIASEIGVKPNLLSLLLWDTKLAKEIFYGPCTSYQYRLQGPGKWAGARAAILTQRERILKPLRTRVVKHSRASLSHLFWVKSVCVVSFFFISVLVIMHLTSV", "length": 538 }, "evidence": [ { "id": "MGI:3643320", "url": "https://alliancegenome.org/gene/MGI:3643320#orthology", "database": "AGR" }, { "id": "FB:FBgn0034943", "url": "https://alliancegenome.org/gene/FB:FBgn0034943#orthology", "database": "AGR" }, { "id": "RGD:1595097", "url": "https://alliancegenome.org/gene/RGD:1595097#orthology", "database": "AGR" }, { "id": "SGD:S000001219", "url": "https://alliancegenome.org/gene/SGD:S000001219#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZD07-1", "protein_name": "Flavin-containing monooxygenase", "gene_name": "Fmo9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKKRIAVIGAGISGLGAIKCCLDEDLEPTCFERSDDIGGLWKFQKNPSEKMPSIYKSVTINTSKEMMCFSDFPIPDHFPNYMHNCKLMDYFRMYAEHFGLLDHIRFKTTVRSVRKRPDFSVQGQWDVIVEADGKQESLVFDGILVCSGHHTDPHLPLKSFPGIEKFEGCYFHSREYKSPEDYVGKRIIVVGIGNSGVDIAVELGRVAKQVFLSTRRGSWILHRVWNNGYPMDSSFFTRFNSFLQKLLSTEAVNKYLEKMMNSRFNHAHYGLQPQHRPLSQHPTVSDDLPNHIISGKVQVKPNVKEFRGTDVVFDDGTVEEKIDVVIFATGYSFSFPFLEDLIAVTDNEVSLYKLMFPPDLEKPTLAVIGLIQPLGIVLPISELQSRWAVRVFKGLSKLPSVKIMNADMAQRKKAMAKRYVKTVRHTIQVDHIEYMDEIAALAGVKPNLLLLFLSDPLLAMEVFFGPCTPYQYRLQGPGKWDGARRAILTQRERIIKPLKTRITSEKSHSAPGLFWIKMTLFGLAFLVISLIYFSYICYEKRK", "length": 543 }, "evidence": [ { "id": "FB:FBgn0034943", "url": "https://alliancegenome.org/gene/FB:FBgn0034943#orthology", "database": "AGR" }, { "id": "RGD:1595083", "url": "https://alliancegenome.org/gene/RGD:1595083#orthology", "database": "AGR" }, { "id": "SGD:S000001219", "url": "https://alliancegenome.org/gene/SGD:S000001219#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A6T0-1", "protein_name": "Flavin-containing monooxygenase", "gene_name": "Fmo13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVKQIAIIGAGVSGLGAIKCCLEEGLEPTCFEKSNDIGGLWRYEETTERPGIYKSLTCNTSKEMTAFSDYPIPDHYPNYMHNSKMMEYLRMYARHFGLMKHIQFQTRVCRVRKRPDFSSSGQWDVVVEVDGKQKTYVFDGVMVCSGHSTEKCLPLQDFAGISKFQGKYLHSWEYRHPDSFVGKRVVVIGIGNSGADVAGEISHVAEQVFLSTRRGAWIWNRVWDNGNPLDTTLFTRYNRTIQKFYPTFLINRWAENKLNARFNHANYGLQAKHRFLSHQSIFSDNLPNHIITGRVLVKPNVKEFTPTSAIFEDGSEEIVDNVVFATGYTFSFPFLDDSSKILDSEHTMFKFVFPPQLEMPTLAFIGILQPVGATIPTSELQSRWVTRVFTGLQKLPSQSNMMADINKRKRKMEKEFVKSPRGIHRVQYIDYMDEIASELGVKPNLLSLFLWDTKLAKEIFWGPCTPYQYRLQGPGKWAGARVAILTQRDRILKPLKTRVLKNCETSSSSLFWVRYICAVIVLFVPVLLILLVIYQ", "length": 536 }, "evidence": [ { "id": "FB:FBgn0034943", "url": "https://alliancegenome.org/gene/FB:FBgn0034943#orthology", "database": "AGR" }, { "id": "RGD:1559819", "url": "https://alliancegenome.org/gene/RGD:1559819#orthology", "database": "AGR" }, { "id": "SGD:S000001219", "url": "https://alliancegenome.org/gene/SGD:S000001219#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3X946-1", "protein_name": "Flavin-containing monooxygenase", "gene_name": "Gm4847", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGVKRIAVIGAGVSGLGAIKCCLEEGLEPTCFEKKSDIGGLWKYEEIPKSGNLGIYKSLTCNTSKEMTAFSDYPIPDHYPNYMHHSKMMEYLRMYARHFGLMKHIQFQTNVCNIKKRPDFSSSGQWDVVVETEEMQKTYIFDGIMVCSGHYTEKYFPLQDFEGISKFQGSYLHTWEYKHPDNFVGKRVAVIGLGNSGADVAGEISRVADQVFLSTRQGAWIWNRVWDHGEPMDTTVFTRYNRAVQKICPRYIINRQMEKKLNGRFNHANYGLLPTHRILEQRTVLSDDLPNRIIIGKVKIKPNVKEFTSTSAIFEDGTKENIDVVIFATGYKLSFPFLSDDSGVLDNQYSMFKYVFPPELEKPTLAFIGILQPAGAILPTSELQSRWVVHVFKGIKKLPSRRAMIADINRKNHQIMAKGSKKILQDHRRVTFVDYMDEIASEIGVKPNLLSLLLWDTKLAKEVFCGPCTSYQYRLQGPGKWDGARAAILTQRERMLKPLRTRVVKQSHLSHLSWVKSACVVVFFFISVVVIMHITSH", "length": 537 }, "evidence": [ { "id": "MGI:3643320", "url": "https://alliancegenome.org/gene/MGI:3643320#orthology", "database": "AGR" }, { "id": "FB:FBgn0034943", "url": "https://alliancegenome.org/gene/FB:FBgn0034943#orthology", "database": "AGR" }, { "id": "RGD:1595097", "url": "https://alliancegenome.org/gene/RGD:1595097#orthology", "database": "AGR" }, { "id": "SGD:S000001219", "url": "https://alliancegenome.org/gene/SGD:S000001219#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMN6-1", "protein_name": "Flavin-containing monooxygenase", "gene_name": "Fmo6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGKKVAIVGAGVSGLAAIRCCLEEGLDPICFERSIDVGGLWKFSSHAEEGRASIYQSVFTNSSKEMMCFPDFPYPDDFPNYMHHSKLQEYITSFAQKKGLLRYIQFETLVSSIKKCSSFLTTGQWVVVTEKEGKQESVLFDAVMICSGHHVYPNMPTDSFPGLEHFRGKCLHSRDYKGPGAFQGKKVLVIGLGNSASDIAVELSRLATQVIISTRSGSWIMSRVWNDGYPWDMVYVTRFTSFLRNILPSFVSDWLYIKKMNTWFKHENYGLMPLNGPLRKEPVFNDELPSRILCGMVTIKPIVTKFTETSAVFEDGTVFEAIDCVIFATGYGYAYPFLDDSIIKSRNNEVTLYKGIFPPQLEKPTMAVIGLVQSLGAAIPTADLQARWAAKVFTNTCVLPTTNEMMDDIDEKMGKKLKWFGQSHTLQTDYITYMDELSSFIGAKPNIPWLFLTDPQLALEVYFGPCSPYQFRLMGPGKWDGARNAILTQWKRTVKPTRTRAVGEAQRPRHLYDLLRMLFFPVFFLAVLLTFY", "length": 532 }, "evidence": [ { "id": "MGI:2681841", "url": "https://alliancegenome.org/gene/MGI:2681841#orthology", "database": "AGR" }, { "id": "HGNC:24024", "url": "https://alliancegenome.org/gene/HGNC:24024#orthology", "database": "AGR" }, { "id": "FB:FBgn0034943", "url": "https://alliancegenome.org/gene/FB:FBgn0034943#orthology", "database": "AGR" }, { "id": "RGD:1559491", "url": "https://alliancegenome.org/gene/RGD:1559491#orthology", "database": "AGR" }, { "id": "SGD:S000001219", "url": "https://alliancegenome.org/gene/SGD:S000001219#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0R553-1", "protein_name": "Flavin-containing monooxygenase", "gene_name": "Fmo6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGKKVAIVGAGVSGLAAIRCCLEEGLEPICFERSNDVGGLWKFSSHVEEGRASIYQSVFTNSSKEMMCFPDFPYPDDFPNYMHHSKLQEYIKSFAQKKDLLRYIQFETLVSSIKKCSSFLTTGQWVVVTEKDGKQESVLFDAVMICSGHHVYPNMPTDSFPGLEHFQGKCMHSRDYKGPGDFQGKKVLVIGLGNSASDIAVEVSRLATQVIISTRSGSWVMSRVWNDGYPWDMVYVTRFASFLRNILPSFVSDWLYVKKMNTWFKHENYGLMPLNGPLRKEPVFNDELPARILCGTVSIKPIVTKFTETSAVFEDGTVFEAIDCVIFATGYGYAYPFLEDSIIKSRNNEVTLYKGIFPPQLEKPTMAVIGLVQSLGAAIPTADLQARWAAKVFTNACVLPTTNEMMDDIDEKMGKKLKWFGQSHTLQTDYITYMDELSSFIGAKPNIPWLFVTDPQLALEVYFGPCSPYQFRLMGPGKWDGARSAILTQWKRTVKPTRTRAVGEAQRPCHLYDLLQMLFFPVFFLAVLLTFY", "length": 532 }, "evidence": [ { "id": "MGI:2681841", "url": "https://alliancegenome.org/gene/MGI:2681841#orthology", "database": "AGR" }, { "id": "HGNC:24024", "url": "https://alliancegenome.org/gene/HGNC:24024#orthology", "database": "AGR" }, { "id": "FB:FBgn0034943", "url": "https://alliancegenome.org/gene/FB:FBgn0034943#orthology", "database": "AGR" }, { "id": "RGD:1559491", "url": "https://alliancegenome.org/gene/RGD:1559491#orthology", "database": "AGR" }, { "id": "SGD:S000001219", "url": "https://alliancegenome.org/gene/SGD:S000001219#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O60774-1", "protein_name": "Putative dimethylaniline monooxygenase [N-oxide-forming] 6", "gene_name": "FMO6P", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSKRVGIIGAGVSGLAAIWCCLEEGLEPTCFERSDDVGGLWKFSDHTEEGRASIYQSVFTNSSKEMMCFPDFPYPDDYPNYIHHSKLQEYIKTYAQKKDLLRYIQFETLVSGIKKCPSFLVTGQWVVVTEKDGKQESTIFDAVMICSGHHVYPNLPTDSFPGLDQFRGNYLHSRDYKNPEAFKGKRVLVIGLGNSGSDIAVELSRLATQVIISTRSASWVMSRVWDDGYPWDMMYVTRFASFLRNVLPSFISDWLYVQKMNTWFKHENYGLMPLNGSLRKEPVFNDELPSRILCGTLSIKPSVKEFTETSAVFEDGTMFEAIDSVIFATGYDYSYPFLDETIMKSRNNEVTLFKGIFPPLMEKPTLAVIGLVQSLGAAIPTADLQAWWAAKVFANSCTLPTTNEMMDDTDEKMGKKLKCMFSSFFMFGQSQTLQTDYITYVDELGSFIGAKPNIPWLFLTDPRLALEVYFGPCSPYQFRLMGPGKWDGARNAILTQWNRTVKPTRTRVVSEVQRPHPFYNLLKMLSFPLLLLAVTLTFY", "length": 539 }, "evidence": [ { "id": "MGI:2681841", "url": "https://alliancegenome.org/gene/MGI:2681841#orthology", "database": "AGR" }, { "id": "HGNC:24024", "url": "https://alliancegenome.org/gene/HGNC:24024#orthology", "database": "AGR" }, { "id": "FB:FBgn0034943", "url": "https://alliancegenome.org/gene/FB:FBgn0034943#orthology", "database": "AGR" }, { "id": "RGD:1559491", "url": "https://alliancegenome.org/gene/RGD:1559491#orthology", "database": "AGR" }, { "id": "SGD:S000001219", "url": "https://alliancegenome.org/gene/SGD:S000001219#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P31512-1", "protein_name": "Dimethylaniline monooxygenase [N-oxide-forming] 4", "gene_name": "FMO4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKKVAVIGAGVSGLSSIKCCVDEDLEPTCFERSDDIGGLWKFTESSKDGMTRVYKSLVTNVCKEMSCYSDFPFHEDYPNFMNHEKFWDYLQEFAEHFDLLKYIQFKTTVCSITKRPDFSETGQWDVVTETEGKQNRAVFDAVMVCTGHFLNPHLPLEAFPGIHKFKGQILHSQEYKIPEGFQGKRVLVIGLGNTGGDIAVELSRTAAQVLLSTRTGTWVLGRSSDWGYPYNMMVTRRCCSFIAQVLPSRFLNWIQERKLNKRFNHEDYGLSITKGKKAKFIVNDELPNCILCGAITMKTSVIEFTETSAVFEDGTVEENIDVVIFTTGYTFSFPFFEEPLKSLCTKKIFLYKQVFPLNLERATLAIIGLIGLKGSILSGTELQARWVTRVFKGLCKIPPSQKLMMEATEKEQLIKRGVFKDTSKDKFDYIAYMDDIAACIGTKPSIPLLFLKDPRLAWEVFFGPCTPYQYRLMGPGKWDGARNAILTQWDRTLKPLKTRIVPDSSKPASMSHYLKAWGAPVLLASLLLICKSSLFLKLVRDKLQDRMSPYLVSLWRG", "length": 558 }, "evidence": [ { "id": "MGI:2429497", "url": "https://alliancegenome.org/gene/MGI:2429497#orthology", "database": "AGR" }, { "id": "HGNC:3772", "url": "https://alliancegenome.org/gene/HGNC:3772#orthology", "database": "AGR" }, { "id": "FB:FBgn0034943", "url": "https://alliancegenome.org/gene/FB:FBgn0034943#orthology", "database": "AGR" }, { "id": "RGD:628601", "url": "https://alliancegenome.org/gene/RGD:628601#orthology", "database": "AGR" }, { "id": "SGD:S000001219", "url": "https://alliancegenome.org/gene/SGD:S000001219#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P31513-1", "protein_name": "Flavin-containing monooxygenase 3", "gene_name": "FMO3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGKKVAIIGAGVSGLASIRSCLEEGLEPTCFEKSNDIGGLWKFSDHAEEGRASIYKSVFSNSSKEMMCFPDFPFPDDFPNFMHNSKIQEYIIAFAKEKNLLKYIQFKTFVSSVNKHPDFATTGQWDVTTERDGKKESAVFDAVMVCSGHHVYPNLPKESFPGLNHFKGKCFHSRDYKEPGVFNGKRVLVVGLGNSGCDIATELSRTAEQVMISSRSGSWVMSRVWDNGYPWDMLLVTRFGTFLKNNLPTAISDWLYVKQMNARFKHENYGLMPLNGVLRKEPVFNDELPASILCGIVSVKPNVKEFTETSAIFEDGTIFEGIDCVIFATGYSFAYPFLDESIIKSRNNEIILFKGVFPPLLEKSTIAVIGFVQSLGAAIPTVDLQSRWAAQVIKGTCTLPSMEDMMNDINEKMEKKRKWFGKSETIQTDYIVYMDELSSFIGAKPNIPWLFLTDPKLAMEVYFGPCSPYQFRLVGPGQWPGARNAILTQWDRSLKPMQTRVVGRLQKPCFFFHWLKLFAIPILLIAVFLVLT", "length": 532 }, "evidence": [ { "id": "MGI:1100496", "url": "https://alliancegenome.org/gene/MGI:1100496#orthology", "database": "AGR" }, { "id": "HGNC:3771", "url": "https://alliancegenome.org/gene/HGNC:3771#orthology", "database": "AGR" }, { "id": "FB:FBgn0034943", "url": "https://alliancegenome.org/gene/FB:FBgn0034943#orthology", "database": "AGR" }, { "id": "RGD:619761", "url": "https://alliancegenome.org/gene/RGD:619761#orthology", "database": "AGR" }, { "id": "SGD:S000001219", "url": "https://alliancegenome.org/gene/SGD:S000001219#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P36365-1", "protein_name": "Flavin-containing monooxygenase 1", "gene_name": "Fmo1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVKRVAIVGAGVSGLASIKCCLEEGLEPTCFERSCDLGGLWRFTEHVEEGRASLYNSVVSNSSKEMSCYSDFPFPEDYPNFVPNSLFLEYLQLYATQFNLLRCIYFNTKVCSITKRPDFAVSGQWEVVTVCQGKQSSDTFDAVMVCTGFLTNPHLPLDSFPGIQTFKGQYFHSRQYKHPDVFKDKRVLVVGMGNSGTDIAVEASHLAKKVFLSTTGGAWVISRVFDSGYPWDMIFMTRFQNMLRNLLPTPVVSWLISKKMNSWFNHVNYGVAPEDRTQLREPVLNDELPGRIITGKVLIKPSIKEVKENSVVFNNTPKEEPIDVIVFATGYSFAFPFLDESIVKVEDGQASLYKYIFPAHLPKPTLAVIGLIKPLGSMIPTGETQARWVVQVLKGATTLPPPSVMMKEVNERKKNKHSGFGLCYCKALQSDYITYIDDLLTSINAKPDLRAMLLTDPRLALSIFFGPCTPYHFRLTGPGKWEGARKAILTQWDRTVNVTKTRTVQETPSTFETLLKLFSFLALLVAVFFIFL", "length": 532 }, "evidence": [ { "id": "MGI:1310002", "url": "https://alliancegenome.org/gene/MGI:1310002#orthology", "database": "AGR" }, { "id": "HGNC:3769", "url": "https://alliancegenome.org/gene/HGNC:3769#orthology", "database": "AGR" }, { "id": "FB:FBgn0034943", "url": "https://alliancegenome.org/gene/FB:FBgn0034943#orthology", "database": "AGR" }, { "id": "RGD:2622", "url": "https://alliancegenome.org/gene/RGD:2622#orthology", "database": "AGR" }, { "id": "SGD:S000001219", "url": "https://alliancegenome.org/gene/SGD:S000001219#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P38866-1", "protein_name": "Thiol-specific monooxygenase", "gene_name": "FMO1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTVNDKKRLAIIGGGPGGLAAARVFSQSLPNFEIEIFVKDYDIGGVWHYPEQKSDGRVMYDHLETNISKKLMQFSGFPFEENVPLYPSRRNIWEYLKAYYKTFIANKDAISIHFSTEVTYLKKKNSQWEITSKDELRTTKSDFDFVIVASGHYSVPKLPTNIAGLDLWFDNKGAFHSKDFKNCEFAREKVVIVVGNGSSGQDIANQLTTVAKKVYNSIKEPASNQLKAKLIETVQTIDSADWKNRSVTLSDGRVLQNIDYIIFATGYYYSFPFIEPSVRLEVLGEGVTGDKHSSVNLHNLWEHMIYVKDPTLSFILTPQLVIPFPLSELQAAIMVEVFCKSLPITTTFDSNACGTHNFPKGKDLEYYAELQELLNSIPRRVGHFEPVVWDDRLIDLRNSSYTDKEERNVLLAEHAQALKKKKAPYFLPAPHT", "length": 432 }, "evidence": [ { "id": "MGI:3643320", "url": "https://alliancegenome.org/gene/MGI:3643320#orthology", "database": "AGR" }, { "id": "MGI:1310004", "url": "https://alliancegenome.org/gene/MGI:1310004#orthology", "database": "AGR" }, { "id": "MGI:1310002", "url": "https://alliancegenome.org/gene/MGI:1310002#orthology", "database": "AGR" }, { "id": "MGI:2681841", "url": "https://alliancegenome.org/gene/MGI:2681841#orthology", "database": "AGR" }, { "id": "MGI:2429497", "url": "https://alliancegenome.org/gene/MGI:2429497#orthology", "database": "AGR" }, { "id": "MGI:1100496", "url": "https://alliancegenome.org/gene/MGI:1100496#orthology", "database": "AGR" }, { "id": "MGI:1916776", "url": "https://alliancegenome.org/gene/MGI:1916776#orthology", "database": "AGR" }, { "id": "HGNC:3769", "url": "https://alliancegenome.org/gene/HGNC:3769#orthology", "database": "AGR" }, { "id": "HGNC:3771", "url": "https://alliancegenome.org/gene/HGNC:3771#orthology", "database": "AGR" }, { "id": "HGNC:3772", "url": "https://alliancegenome.org/gene/HGNC:3772#orthology", "database": "AGR" }, { "id": "HGNC:3770", "url": "https://alliancegenome.org/gene/HGNC:3770#orthology", "database": "AGR" }, { "id": "HGNC:3773", "url": "https://alliancegenome.org/gene/HGNC:3773#orthology", "database": "AGR" }, { "id": "HGNC:24024", "url": "https://alliancegenome.org/gene/HGNC:24024#orthology", "database": "AGR" }, { "id": "FB:FBgn0034943", "url": "https://alliancegenome.org/gene/FB:FBgn0034943#orthology", "database": "AGR" }, { "id": "RGD:1595083", "url": "https://alliancegenome.org/gene/RGD:1595083#orthology", "database": "AGR" }, { "id": "RGD:628602", "url": "https://alliancegenome.org/gene/RGD:628602#orthology", "database": "AGR" }, { "id": "RGD:628601", "url": "https://alliancegenome.org/gene/RGD:628601#orthology", "database": "AGR" }, { "id": "RGD:1559491", "url": "https://alliancegenome.org/gene/RGD:1559491#orthology", "database": "AGR" }, { "id": "RGD:628600", "url": "https://alliancegenome.org/gene/RGD:628600#orthology", "database": "AGR" }, { "id": "RGD:619761", "url": "https://alliancegenome.org/gene/RGD:619761#orthology", "database": "AGR" }, { "id": "RGD:2622", "url": "https://alliancegenome.org/gene/RGD:2622#orthology", "database": "AGR" }, { "id": "RGD:1595097", "url": "https://alliancegenome.org/gene/RGD:1595097#orthology", "database": "AGR" }, { "id": "RGD:1559819", "url": "https://alliancegenome.org/gene/RGD:1559819#orthology", "database": "AGR" }, { "id": "SGD:S000001219", "url": "https://alliancegenome.org/gene/SGD:S000001219#orthology", "database": "AGR" }, { "id": "Q9W1E9", "url": "https://omabrowser.org/oma/group/Q9W1E9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P49326-1", "protein_name": "Flavin-containing monooxygenase 5", "gene_name": "FMO5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTKKRIAVIGGGVSGLSSIKCCVEEGLEPVCFERTDDIGGLWRFQENPEEGRASIYKSVIINTSKEMMCFSDYPIPDHYPNFMHNAQVLEYFRMYAKEFDLLKYIRFKTTVCSVKKQPDFATSGQWEVVTESEGKKEMNVFDGVMVCTGHHTNAHLPLESFPGIEKFKGQYFHSRDYKNPEGFTGKRVIIIGIGNSGGDLAVEISQTAKQVFLSTRRGAWILNRVGDYGYPADVLFSSRLTHFIWKICGQSLANKYLEKKINQRFDHEMFGLKPKHRALSQHPTLNDDLPNRIISGLVKVKGNVKEFTETAAIFEDGSREDDIDAVIFATGYSFDFPFLEDSVKVVKNKISLYKKVFPPNLERPTLAIIGLIQPLGAIMPISELQGRWATQVFKGLKTLPSQSEMMAEISKAQEEIDKRYVESQRHTIQGDYIDTMEELADLVGVRPNLLSLAFTDPKLALHLLLGPCTPIHYRVQGPGKWDGARKAILTTDDRIRKPLMTRVVERSSSMTSTMTIGKFMLALAFFAIIIAYF", "length": 533 }, "evidence": [ { "id": "MGI:1310004", "url": "https://alliancegenome.org/gene/MGI:1310004#orthology", "database": "AGR" }, { "id": "HGNC:3773", "url": "https://alliancegenome.org/gene/HGNC:3773#orthology", "database": "AGR" }, { "id": "FB:FBgn0034943", "url": "https://alliancegenome.org/gene/FB:FBgn0034943#orthology", "database": "AGR" }, { "id": "RGD:628602", "url": "https://alliancegenome.org/gene/RGD:628602#orthology", "database": "AGR" }, { "id": "SGD:S000001219", "url": "https://alliancegenome.org/gene/SGD:S000001219#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P50285-1", "protein_name": "Flavin-containing monooxygenase 1", "gene_name": "Fmo1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVKRVAIVGAGVSGLASIKCCLEEGLEPTCFERSSDLGGLWRFTEHVEEGRASLYKSVVSNSSREMSCYPDFPFPEDYPNFVPNSLFLEYLKLYSTQFNLQRCIYFNTKVCSITKRPDFAVSGQWEVVTVTNGKQNSAIFDAVMVCTGFLTNPHLPLDSFPGILTFKGEYFHSRQYKHPDIFKDKRVLVVGMGNSGTDIAVEASHLAKKVFLSTTGGAWVISRVFDSGYPWDMIFMTRFQNMLRNLLPTPIVSWLISKKMNSWFNHVNYGVAPEDRTQLREPVLNDELPGRIITGKVFIKPSIKEVKENSVVFNNTPKEEPIDIIVFATGYTFAFPFLDESVVKVEDGQASLYKYIFPAHLPKPTLAVIGLIKPLGSMVPTGETQARWVVQVLKGATTLPPPSVMMEEVNERKKNKHSGFGLCYCKALQTDYITYIDDLLTSINAKPDLRAMLLTDPRLALSIFFGPCTPYHFRLTGPGKWEGARKAILTQWDRTVKVTKTRTIQESPSSFETLLKLFSFLALLIAVFLIFL", "length": 532 }, "evidence": [ { "id": "MGI:1310002", "url": "https://alliancegenome.org/gene/MGI:1310002#orthology", "database": "AGR" }, { "id": "HGNC:3769", "url": "https://alliancegenome.org/gene/HGNC:3769#orthology", "database": "AGR" }, { "id": "FB:FBgn0034943", "url": "https://alliancegenome.org/gene/FB:FBgn0034943#orthology", "database": "AGR" }, { "id": "RGD:2622", "url": "https://alliancegenome.org/gene/RGD:2622#orthology", "database": "AGR" }, { "id": "SGD:S000001219", "url": "https://alliancegenome.org/gene/SGD:S000001219#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P97501-1", "protein_name": "Flavin-containing monooxygenase 3", "gene_name": "Fmo3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKKVAIIGAGVSGLAAIRSCLEEGLEPTCFERSDDVGGLWKFSDHIEEGRASIYQSVFTNSSKEMMCFPDFPYPDDFPNFMHHSKLQEYITSFAKEKNLLKYIQFETPVTSINKCPNFSTTGKWEVTTEKHGKKETAVFDATMICSGHHIFPHVPKDSFPGLNRFKGKCFHSRDYKEPGIWKGKRVLVIGLGNSGCDIAAELSHVAQKVTISSRSGSWVMSRVWDDGYPWDMVVLTRFQTFLKNNLPTAISDWWYTRQMNARFKHENYGLVPLNRTLRKEPVFNDELPARILCGMVTIKPNVKEFTETSAVFEDGTMFEAIDCVIFATGYGYAYPFLDDSIIKSRNNEVTLYKGVFPPQLEKPTMAVIGLVQSLGATIPITDLQARWAAQVIKGTCTLPSVNDMMDDIDEKMGEKFKWYGNSTTIQTDYIVYMDELASFIGAKPNLLWLFLKDPRLAVEVFFGPCSPYQFRLVGPGKWSGARNAILTQWDRSLKPMKTRVVSKVQKSCSHFYSRLLRLLAVPVLLIALFLVLI", "length": 534 }, "evidence": [ { "id": "MGI:1100496", "url": "https://alliancegenome.org/gene/MGI:1100496#orthology", "database": "AGR" }, { "id": "HGNC:3771", "url": "https://alliancegenome.org/gene/HGNC:3771#orthology", "database": "AGR" }, { "id": "FB:FBgn0034943", "url": "https://alliancegenome.org/gene/FB:FBgn0034943#orthology", "database": "AGR" }, { "id": "RGD:619761", "url": "https://alliancegenome.org/gene/RGD:619761#orthology", "database": "AGR" }, { "id": "SGD:S000001219", "url": "https://alliancegenome.org/gene/SGD:S000001219#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P97872-1", "protein_name": "Flavin-containing monooxygenase 5", "gene_name": "Fmo5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKKRIAVIGAGASGLTCIKCCLEEGLEPVCFERSGDIGGLWRFQEAPEEGRASIYQSVVINTSKEMMCFSDYPIPDHYPNYMHNSQVLEYFRMYAKEFDLLKYIQFKTTVCSVKKQPDFSTSGQWQVVTECEGKQQVDVFDGVLVCTGHHTDAHLPLESFPGIEKFKGKYFHSRDYKNPVEFTGKRVIVIGIGNSGGDLAVEISHTAKQVFLSTRRGAWILNRVGKHGYPIDLLLSSRIMYYLSRICGPSLKNNYMEKQMNQRFDHEMFGLKPKHRALSQHPTVNDDLPNRIIAGLVKVKGNVKEFTETAAVFEDGSREDGIDVVIFATGYSFAFPFLEDSVKVVKNKVSLYKKVFPPNLEKPTLAIIGLIQPLGAIMPISELQGRWATQVFKGLKKLPSQSEMMAEINKAREEMAKRYVDSQRHTIQGDYIDTMEEIADLVGVRPNILPLVFTDPRLALRLLLGPCTPVQYRLQGPGKWAGARKTILTTEDRVRKPLMTRVVERDSSGGSLVTVRVLMLAVAFFAVILAYF", "length": 533 }, "evidence": [ { "id": "MGI:1310004", "url": "https://alliancegenome.org/gene/MGI:1310004#orthology", "database": "AGR" }, { "id": "HGNC:3773", "url": "https://alliancegenome.org/gene/HGNC:3773#orthology", "database": "AGR" }, { "id": "FB:FBgn0034943", "url": "https://alliancegenome.org/gene/FB:FBgn0034943#orthology", "database": "AGR" }, { "id": "RGD:628602", "url": "https://alliancegenome.org/gene/RGD:628602#orthology", "database": "AGR" }, { "id": "SGD:S000001219", "url": "https://alliancegenome.org/gene/SGD:S000001219#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q01740-1", "protein_name": "Flavin-containing monooxygenase 1", "gene_name": "FMO1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKRVAIVGAGVSGLASIKCCLEEGLEPTCFERSDDLGGLWRFTEHVEEGRASLYKSVVSNSCKEMSCYSDFPFPEDYPNYVPNSQFLEYLKMYANHFDLLKHIQFKTKVCSVTKCSDSAVSGQWEVVTMHEEKQESAIFDAVMVCTGFLTNPYLPLDSFPGINAFKGQYFHSRQYKHPDIFKDKRVLVIGMGNSGTDIAVEASHLAEKVFLSTTGGGWVISRIFDSGYPWDMVFMTRFQNMLRNSLPTPIVTWLMERKINNWLNHANYGLIPEDRTQLKEFVLNDELPGRIITGKVFIRPSIKEVKENSVIFNNTSKEEPIDIIVFATGYTFAFPFLDESVVKVEDGQASLYKYIFPAHLQKPTLAIIGLIKPLGSMIPTGETQARWAVRVLKGVNKLPPPSVMIEEINARKENKPSWFGLCYCKALQSDYITYIDELLTYINAKPNLFSMLLTDPHLALTVFFGPCSPYQFRLTGPGKWEGARNAIMTQWDRTFKVIKARVVQESPSPFESFLKVFSFLALLVAIFLIFL", "length": 532 }, "evidence": [ { "id": "MGI:1310002", "url": "https://alliancegenome.org/gene/MGI:1310002#orthology", "database": "AGR" }, { "id": "HGNC:3769", "url": "https://alliancegenome.org/gene/HGNC:3769#orthology", "database": "AGR" }, { "id": "FB:FBgn0034943", "url": "https://alliancegenome.org/gene/FB:FBgn0034943#orthology", "database": "AGR" }, { "id": "RGD:2622", "url": "https://alliancegenome.org/gene/RGD:2622#orthology", "database": "AGR" }, { "id": "SGD:S000001219", "url": "https://alliancegenome.org/gene/SGD:S000001219#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5TZD3-1", "protein_name": "Flavin-containing monooxygenase", "gene_name": "si:dkey-239i20.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAKRVAIIGGGTSGLACIKCCLDEGLEPVCFETSDDIGGLWRFKENPDLDQASIYHSLIINTSKEMMCYSDYPIPAHFPNYMHNSLIMEYFRMYAENFQLKRHIRFQTRVLHVTPRPDFPHSGQWDVETESKDGLREKQVFDAVMVCTGHHCHPHLPLKDFPGIDTFKGKFFHSRDYKNPEDWRGKRAVVIGIGNSGGDIAVELSRMAKQVYLSTRKGSWILNRVGDSGVPFDMMFNNRAVMWFLDSLPVKYRNKLGESRLNKRFDHKLYGLQPEHRIFSQHPMVNDDLPNRILSGTVSVKPNVQEFRGSSVVFEDGTVEDNIDLVVFATGYTFSFPFLSSHVIPVSNNKVSLYKFVYPPGLERSTLAVIGLIQPLGAIMPISEMQARWATRVFKGLCKLPSKNAMMKDIKAKEQAMTQRYVAAQRHTIQVDYIPYMDELAKQVGVRPSIPRLLLTDPRLAFKVIFGPCTPYQFRLHGPGQWEGARQAILTQWDRVVEPLKTRCTKEPQSQSFSHSLIFSVSVAGLLSALYYGRASLQTFLENPSALLDKIRGFVPLPMPTQ", "length": 562 }, "evidence": [ { "id": "MGI:1310004", "url": "https://alliancegenome.org/gene/MGI:1310004#orthology", "database": "AGR" }, { "id": "MGI:2681841", "url": "https://alliancegenome.org/gene/MGI:2681841#orthology", "database": "AGR" }, { "id": "MGI:1100496", "url": "https://alliancegenome.org/gene/MGI:1100496#orthology", "database": "AGR" }, { "id": "MGI:1916776", "url": "https://alliancegenome.org/gene/MGI:1916776#orthology", "database": "AGR" }, { "id": "HGNC:3771", "url": "https://alliancegenome.org/gene/HGNC:3771#orthology", "database": "AGR" }, { "id": "HGNC:3772", "url": "https://alliancegenome.org/gene/HGNC:3772#orthology", "database": "AGR" }, { "id": "HGNC:3770", "url": "https://alliancegenome.org/gene/HGNC:3770#orthology", "database": "AGR" }, { "id": "HGNC:3773", "url": "https://alliancegenome.org/gene/HGNC:3773#orthology", "database": "AGR" }, { "id": "HGNC:24024", "url": "https://alliancegenome.org/gene/HGNC:24024#orthology", "database": "AGR" }, { "id": "RGD:1595083", "url": "https://alliancegenome.org/gene/RGD:1595083#orthology", "database": "AGR" }, { "id": "RGD:628602", "url": "https://alliancegenome.org/gene/RGD:628602#orthology", "database": "AGR" }, { "id": "RGD:1559491", "url": "https://alliancegenome.org/gene/RGD:1559491#orthology", "database": "AGR" }, { "id": "RGD:628600", "url": "https://alliancegenome.org/gene/RGD:628600#orthology", "database": "AGR" }, { "id": "RGD:619761", "url": "https://alliancegenome.org/gene/RGD:619761#orthology", "database": "AGR" }, { "id": "RGD:2622", "url": "https://alliancegenome.org/gene/RGD:2622#orthology", "database": "AGR" }, { "id": "RGD:1595097", "url": "https://alliancegenome.org/gene/RGD:1595097#orthology", "database": "AGR" }, { "id": "RGD:1559819", "url": "https://alliancegenome.org/gene/RGD:1559819#orthology", "database": "AGR" }, { "id": "SGD:S000001219", "url": "https://alliancegenome.org/gene/SGD:S000001219#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6IRI9-1", "protein_name": "Dimethylaniline monooxygenase [N-oxide-forming] 2", "gene_name": "Fmo2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVKKVAVIGAGVSGLISLKGCVDEGLEPTCFERTEDIGGLWRFKENVEDGRASIYHSVITNTSKEMSCFSDFPMPEDFPNFLHNSKLLEYFRIFAKKFDLLKYIQFQTTVISVKKRPDFASSGQWDVYVQSNGKEQRAVFDAVMVCSGHHIQPHLPLKSFPGIERFQGQYFHSRQYKHPVGYEGKRILVVGIGNSAADIASELSKRAAQVFVSTRHGSWVLSRISEDGYPWDMVFHTRFSSMLRNVLPRTVVKWMMERQMNRWFNHENYGLVPQNKYLMKEPVLNDDLPSRLLYGAIKVKTRVKELTETAVVFEDGTVEEDVDVIVFATGYTFSFPFLEDSLVKVEDNKVSLYKAMFPPHLEKPTLACIGLIQPLGSIFPTVELQARWATRVFKGVCRLPSETTMMADIAERNEKRIDLFGKSQSQILQTNYIDYLDELALEIGAKPDFISLLFKDPKLAVKLYFGPCNSYQYRLVGPGQWEGARNAILTQKQRILKPLKTRTLQTSASAPVSFLIKVLGLLAIVLAFFFKLHGF", "length": 535 }, "evidence": [ { "id": "MGI:1916776", "url": "https://alliancegenome.org/gene/MGI:1916776#orthology", "database": "AGR" }, { "id": "HGNC:3770", "url": "https://alliancegenome.org/gene/HGNC:3770#orthology", "database": "AGR" }, { "id": "FB:FBgn0034943", "url": "https://alliancegenome.org/gene/FB:FBgn0034943#orthology", "database": "AGR" }, { "id": "RGD:628600", "url": "https://alliancegenome.org/gene/RGD:628600#orthology", "database": "AGR" }, { "id": "SGD:S000001219", "url": "https://alliancegenome.org/gene/SGD:S000001219#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8K2I3-1", "protein_name": "Dimethylaniline monooxygenase [N-oxide-forming] 2", "gene_name": "Fmo2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKKVVVIGAGVSGLISLKCCVDEGLEPTCFERTEDIGGLWRFKENVEDGRASIYRSVITNTSKEMSCFSDFPMPEDFPNFLHNSKLLEYFRIFAKKFDLLKYIQFQTTVISVKKRPDFASSGQWEVYTQSNGKEQRTVFDAVMVCSGHHIQPHLPLKSFPGIERFRGQYFHSREYKHPVGFEGKRILVVGIGNSAADIASELSKTAAQVFVSTRHGSWVMSRISEDGYPWDMVFHTRFSSMLRNVLPRTVVKWMMEQQMNRWFNHENYGLVPQNKYLMKEPVLNDDLPSRLLYGAIKVKTRVKELTETAVVFEDGTVEEDVDIIVFATGYTFSFSFLEDSLVKVEDNRVSLYKAMFPPHLEKPTLACIGLIQPLGSIFPTVELQARWATRVFKGLCSLPSETTMMADIVERNEKRVNLFGKSQSQILQTNYVDYLDELALEIGAKPDFVSLFFKDPKLAVKLYFGPCNSYQYRLVGPGQWEGARNAILTQKQRILKPLKTRTLQSSDSAPVSFLLKILGLLAVVLAFFFQLQGF", "length": 535 }, "evidence": [ { "id": "MGI:1916776", "url": "https://alliancegenome.org/gene/MGI:1916776#orthology", "database": "AGR" }, { "id": "HGNC:3770", "url": "https://alliancegenome.org/gene/HGNC:3770#orthology", "database": "AGR" }, { "id": "FB:FBgn0034943", "url": "https://alliancegenome.org/gene/FB:FBgn0034943#orthology", "database": "AGR" }, { "id": "RGD:628600", "url": "https://alliancegenome.org/gene/RGD:628600#orthology", "database": "AGR" }, { "id": "SGD:S000001219", "url": "https://alliancegenome.org/gene/SGD:S000001219#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8K4B7-1", "protein_name": "Dimethylaniline monooxygenase [N-oxide-forming] 4", "gene_name": "Fmo4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKKVAVIGAGVSGLSSIKCCLDENLEPTCFERSSDFGGLWKFAEASEDGMTRVYRSLVTNVCKEMSCYSDFPFHEDYPNFMSHEKFWDYLREFAEHFGLLKYIRFKTTVRSVTKRPDFSETGQWEVVTETEGKQDRAVFDAVMVCTGQFLSPRLPLESFPGIHKFKGQILHSQEYRIPDAFRGKRILVVGLGNTGGDVAVELSGIAAQVFLSTRTGAWVRSRSSVGGYPLNMMQTRWRNFLAQVLPSRFVSWNQERQMNKIFNHENYGLSIAKGKKPKFIVNDELPTCILCGKITMKTSVKDFTESSIVFEDGTIEANIDVVIFTTGYEFSFPFFEEPLKSLCTKKVILYKRVFPPNLERSTLAIIGLISLTGSILVGTEFQARWATRVFKGLCNIPPSQKLMAEAIKKEELIKRGVIKDTSQDKLDFISYMDELTQCIGAKPNIPLLFLKDPRLAWEVFFGPCTPYQYRLMGPGRWDGARNAILTQWDRTVKPLKTRTVPKSQEPASLSRYLKTWGAPVLIVSLLLIYKSSLFLELVQSKLQGRFSPSRILWYIPQNS", "length": 560 }, "evidence": [ { "id": "MGI:2429497", "url": "https://alliancegenome.org/gene/MGI:2429497#orthology", "database": "AGR" }, { "id": "HGNC:3772", "url": "https://alliancegenome.org/gene/HGNC:3772#orthology", "database": "AGR" }, { "id": "FB:FBgn0034943", "url": "https://alliancegenome.org/gene/FB:FBgn0034943#orthology", "database": "AGR" }, { "id": "RGD:628601", "url": "https://alliancegenome.org/gene/RGD:628601#orthology", "database": "AGR" }, { "id": "SGD:S000001219", "url": "https://alliancegenome.org/gene/SGD:S000001219#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8K4C0-1", "protein_name": "Flavin-containing monooxygenase 5", "gene_name": "Fmo5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKKRIAVIGSGASGLTCIKCCLEEGLEPVCFERSDDIGGLWRYQENPEKGRASIYKSVIINTSKEMMCFSDYPIPDHYPNFMHNSQVLEYFRMYAKEFGLLKYIQFKTTVCSVKKQPDFSTSGQWQVVTEHEGKQQVDVFDGVLVCTGHHTDPHLPLDSFPGIEKFKGKYFHSREYKNPVEFTGKRVIVIGIGNSGGDLAVEISHTAKQVFLSTRRGAWILNRVGKRGYPIDILLSSRITNYLSKICGSALKNRYMEKQLNQRFDHEMFGLKPKHSALGQHPTINDDLPNRIISGLVKVKGNVKEFTETAAIFEDGSREDDIDVVIFATGYSFAFPFLEDSVKVVQNKVSLYKKVFPPNLEKPTLAIIGLIQPLGAIMPISELQGRWATQVFKGLKKLPSQSEMMAEINKTREEMAKRYVDSQRHTIQGDYIDTMEEIADLVGVRPNLLSLAFTDPKLAFQLLVGPCTPVQYRLQGPGKWAGARKTILTTEDRIRKPLMTRVVERDSSGTSLVTVRVLMLAVTFLAVILAYF", "length": 533 }, "evidence": [ { 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{ "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { 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"name": "infantile subacute necrotizing encephalopathy", "description": "" }, { "id": "MONDO:0009723", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009723", "name": "Leigh's necrotizing encephalopathy", "description": "" }, { "id": "MONDO:0009723", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009723", "name": "SNE", "description": "" }, { "id": "MONDO:0009723", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009723", "name": "necrotizing encephalopathy, infantile Subacute, of Leigh", "description": "" }, { "id": "MONDO:0009723", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009723", "name": "subacute necrotizing encephalopathy", "description": "" }, { "id": "MIM:256000", "resource": "MIM", "url": "https://www.omim.org/entry/256000", "name": "Leigh syndrome", "description": "Leigh syndrome" } ], "unlinked_id_list": [], "evidence": [ { "id": "3652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3652" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W1F5", "url": "https://www.uniprot.org/uniprotkb/Q9W1F5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG3803", "url": "https://www.uniprot.org/uniprotkb/Q9W1F5", "locus": { "chromosome": "2R", "start_pos": 23952513, "end_pos": 23954048, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0034938", "url": "https://www.ensemblgenomes.org/id/FBgn0034938" } ] } } ], "crossref": [ { "id": "FB:FBgn0034938", "url": "https://alliancegenome.org/gene/FB:FBgn0034938", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0034938", "url": "https://bgee.org/?page=gene&gene_id=FBgn0034938", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0034938", "url": "https://flybase.org/reports/FBgn0034938", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "37809", "url": "https://www.ncbi.nlm.nih.gov/gene/37809", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003780", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003780", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023754", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023754", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG3803", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3803", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AFVCYSW", "url": "https://omabrowser.org/oma/group/AFVCYSW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W1F5", "url": "https://www.orthodb.org/?gene=Q9W1F5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23289", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23289", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23289:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23289:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02628", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02628", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-189451", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-189451", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-9864848", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9864848", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_611855", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611855", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "63388", "url": "https://www.rhea-db.org/rhea/63388", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q9W1F5", "url": "https://www.uniprot.org/uniprotkb/Q9W1F5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W1F5-1", "url": "https://www.uniprot.org/uniprotkb/Q9W1F5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRLLQKRTNLIKLVVPGPRLHQTIAQTAIKEIPVIKPISTPKSDKTVGRWFLGVSGMVFVAVGLGGVTRLTESGLSMVTWKLTGERMPRTQEEWVQEFNLYQQYPEYKLKNVNMTVEEFKFIFMMEYMHRMWGRAIGGFFLLPAVYFWRKGYFCAKTKKSVLLLGTLIGLQGLMGWYMVKSGLEDRFQDPNDVPRVSQYRLASHLAAAFVLYSLSLSKAMSLLIPTNTFVIQAKKAFNIKGLTHLTKAMVLLTAISGAFVAGLDAGLVYNSFPKMGDKWIPDDMWTFAPIQKNITENPTTVQFNHRILGISTVTLTTALWLVTRRMQLPKRANWAINAVVAMAWTQATLGVTTLLNYVPVPLATAHQSGSLILLSFALWLSHEVRLLKYLPK", "length": 393, "header": "tr|Q9W1F5-1|Q9W1F5_DROME Isoform 1 of Cytochrome c oxidase assembly protein COX15 homolog OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG3803 PE=4 SV=1 CANONICAL=Q9W1F5-1" }, "isoforms": [ { "isoform_ac": "Q9W1F5-1", "url": "https://www.uniprot.org/uniprotkb/Q9W1F5/entry#Q9W1F5-1", "sequence": { "sequence": "MLRLLQKRTNLIKLVVPGPRLHQTIAQTAIKEIPVIKPISTPKSDKTVGRWFLGVSGMVFVAVGLGGVTRLTESGLSMVTWKLTGERMPRTQEEWVQEFNLYQQYPEYKLKNVNMTVEEFKFIFMMEYMHRMWGRAIGGFFLLPAVYFWRKGYFCAKTKKSVLLLGTLIGLQGLMGWYMVKSGLEDRFQDPNDVPRVSQYRLASHLAAAFVLYSLSLSKAMSLLIPTNTFVIQAKKAFNIKGLTHLTKAMVLLTAISGAFVAGLDAGLVYNSFPKMGDKWIPDDMWTFAPIQKNITENPTTVQFNHRILGISTVTLTTALWLVTRRMQLPKRANWAINAVVAMAWTQATLGVTTLLNYVPVPLATAHQSGSLILLSFALWLSHEVRLLKYLPK", "length": 393, "header": "tr|Q9W1F5-1|Q9W1F5_DROME Isoform 1 of Cytochrome c oxidase assembly protein COX15 homolog OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG3803 PE=4 SV=1 CANONICAL=Q9W1F5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W1F5", "url": "https://www.uniprot.org/uniprotkb/Q9W1F5" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W1F5", "url": "https://www.uniprot.org/uniprotkb/Q9W1F5" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1F5", "url": "https://www.uniprot.org/uniprotkb/Q9W1F5" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1F5", "url": "https://www.uniprot.org/uniprotkb/Q9W1F5" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W1F5", "url": "https://www.uniprot.org/uniprotkb/Q9W1F5" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W1F5", "url": "https://www.uniprot.org/uniprotkb/Q9W1F5" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W1F5", "url": "https://www.uniprot.org/uniprotkb/Q9W1F5" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1F5", "url": "https://www.uniprot.org/uniprotkb/Q9W1F5" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1F5", "url": "https://www.uniprot.org/uniprotkb/Q9W1F5" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W1F5", "url": "https://www.uniprot.org/uniprotkb/Q9W1F5" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W1F5", "url": "https://www.uniprot.org/uniprotkb/Q9W1F5" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG3803", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3803", "resource": "KEGG Pathway" }, { "id": "R-DME-189451", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-189451", "resource": "Reactome", "description": "Heme biosynthesis" }, { "id": "R-DME-9864848", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9864848", "resource": "Reactome", "description": "Complex IV assembly" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A414-1", "protein_name": "Cytochrome c oxidase assembly homolog COX15", "gene_name": "Cox15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"id": "Q9W1F5", "url": "https://omabrowser.org/oma/group/Q9W1F5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1NMU0-1", "protein_name": "COX15, cytochrome c oxidase assembly homolog", "gene_name": "COX15", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLRTLCCGGGRFFRLGPSLVPLRQPPRRGLPQQPAPAVPPAVGRWLLACSGAVAGAVVLGGVTRLTESGLSMVDWHLVKEMKPPRTQQEWEAEFQKYQQFPEFKILNHDMTLTEFKFIWYMEYSHRMWGRVVGLAYILPAAYFWRKGWLSRPMKGRVLALCGLVCFQGLLGWYMVKSGLEEKPDSHDIPRVSQYRLAAHLGSALVLYAASLWTGLSLLLPRHQLHETRQLLQLRHFAHGTTALIFLTALSGAFVAGLDAGLVYNSFPKMGERWIPDDLLAFSPTLRNIFENPTTVQFDHRILGTASVTAVTALYLFSRKISLPHRTRIAVTSLLAVAWVQVGLGISTLLLYVPTPLAATHQSGSLALLSVALWLMSELRRMPK", "length": 383 }, "evidence": [ { "id": "Q9W1F5", "url": "https://omabrowser.org/oma/group/Q9W1F5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1R355-1", "protein_name": "1.17.99.9", "gene_name": "cox15", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMLLRLAMCRCQAARNLQQIQRTPLRQWLLQRGQNTVSSGAASVGSVSIRSAASDRLIGRWLLGCSGLVLGAVVLGGVTRLTESGLSMVDWHLVKEMKPPQTQAEWEQEFAKYQQFPEFKIMNHDMTLTEFKFIFYMEWGHRMWGRLVGLAYILPAAYFWRRGYFSRSMKTRVLGLCGFVVFQGLLGWYMVKSGLEEKPESYDVPRVSQYRLAAHLGSALLLYAASLWTGLTLLLPANRMPDSRQLLNLRRFAKMTGGLVFLTALSGAFVAGLDAGLVYNSFPKMGERWIPDDLLAFSPALKNVFENPTTVQFDHRILGIGSLTAITGLYLFSRRMILPRRAKMAISLLTAMAYTQVVLGISTLLLYVPTPLAATHQSGSVALLTFAIWVLAELRKVPK", "length": 399 }, "evidence": [ { "id": "MGI:1920112", "url": "https://alliancegenome.org/gene/MGI:1920112#orthology", "database": "AGR" }, { "id": "HGNC:2263", "url": "https://alliancegenome.org/gene/HGNC:2263#orthology", "database": "AGR" }, { "id": "Q9W1F5", "url": "https://omabrowser.org/oma/group/Q9W1F5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1S8W1-1", "protein_name": "Cytochrome c oxidase assembly homolog COX15", "gene_name": "COX15", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQRLLLPPLKVLMGNPCLRLLVPRAAPRTQCGCSCGIRHSLRPGQYSTITEVGLQSGRGTVSLPSKAAERVVGRWLLVCSGTVAGAVILGGVTRLTESGLSMVDWHLIKEMKPPTSQEEWEAEFQKYQQFPEFKILNHDMTLPEFKFIWYMEYSHRMWGRLVGLAYILPAAYFWRKGWLNRGLKGRVLALCGLVCFQGLLGWYMVKSGLEEKPDSHDIPRVSQYRLAAHLGSALVLYCASLWTSLSLLLPQHKLPETRQLLWLRRCAHGTAGLVFLTALSGAFVAGLDAGLVYNSFPKMGESWIPEDLFTFSPLLKNVFENPTTVQFDHRILGITSVTAITALYFLSRRIPLPRRTKIAAATLLALAYTQVGLGISTLLMYVPTPLAATHQSGSLALLSVALWLMNELRRVPK", "length": 413 }, "evidence": [ { "id": "Q9W1F5", "url": "https://omabrowser.org/oma/group/Q9W1F5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3IBW2-1", "protein_name": "Cytochrome c oxidase assembly protein COX15 homolog isoform X2", "gene_name": "LOC100751499", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MQRLLLPPLKAFVGSRSVGLLVPGPASRAQWGCSFGSRRPLRPGQYGTITEVALQSGKGTVPLPSKAAEQAVGRWLLVCSGTVAGAVILGGVTRLTESGLSMVDWHLIKEMKPPTSQEEWEAEFQKYQQFPEFKILNHDMTLAEFKFIWYMEYSHRMWGRAVGLAYILPAAYFWRKGWLSRGMKGRVLALCGLVCFQGLLGWYMVKSGLEEKPESYDIPRVSQYRLAAHLGSALVLYCASLWTSLSLLLPQHKLPETQQLLWLRRFAGGTAGLVFLTALSGAFVAGLDAGLVYNSFPKMGDSWIPEDLLTFSPILKNVFENPTMVQFDHRLLGITSVTAITALYFLSRRVPLPRRTKMAAVTLLALAYTQVALGISTLLMYVPTPLAATHQSGSLALLSGALWLMNELRRVPK", "length": 413 }, "evidence": [ { "id": "Q9W1F5", "url": "https://omabrowser.org/oma/group/Q9W1F5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O76740-1", "protein_name": "Cytochrome c oxidase assembly protein", "gene_name": "coxA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLNRAGLRCLKPSIFKQTKSNLIINNSNILSVSSRLSKNNNINQSFNNGFLQSNSKLNSIISLNNNNNNYYKRFYSNENKTNSNEQVKEEEKTNDNSSNNNEEDYKEPEQSKGNKKVGNWLLFSCGLVGAMIVIGGITRLTESGLSIVDWKPVVGAIPPITQEEWEAEFEKYKQFPEYKRLNMGMTLSEFKEIFFWEYSHRLLGRVIGVAFFFPFVWYLKKGYINRSLAKKLSVVFLMGGAQGALGWYMVKSGLDEKLIQDRGSDIPRVSQYRLAAHLGSAFVIYMALLWFGLGLVRPSALSPAMMQKLKSAMSTLAQQKSSFTIEKMKKYSHQVSGLIFLTAMSGAFVAGLDAGLVYNTFPKMGHQWIPDDIINPKIKPAYKNMFEHDVTVQFQHRVLATITYGSILALSAFAYRGRLALSPKARLATNCLLAVGTAQVALGITTLLTFVPVSLGAAHQTGSLTLLSVAIWLLHELKKLPK", "length": 482 }, "evidence": [ { "id": "Q9W1F5", "url": "https://omabrowser.org/oma/group/Q9W1F5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P40086-1", "protein_name": "Heme A synthase COX15", "gene_name": "COX15", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLFRNIEVGRQAAKLLTRTSSRLAWQSIGASRNISTIRQQIRKTQLYNFKKTVSIRPFSLSSPVFKPHVASESNPIESRLKTSKNVAYWLIGTSGLVFGIVVLGGLTRLTESGLSITEWKPVTGTLPPMNQKEWEEEFIKYKESPEFKLLNSHIDLDEFKFIFFMEWIHRLWGRAIGAVFILPAVYFAVSKKTSGHVNKRLFGLAGLLGLQGFVGWWMVKSGLDQEQLDARKSKPTVSQYRLTTHLGTAFFLYMGMLWTGLEILRECKWIKNPVQAISLFKKLDNPAIGPMRKISLALLAVSFLTAMSGGMVAGLDAGWVYNTWPKMGERWFPSSRELMDENFCRREDKKDLWWRNLLENPVTVQLVHRTCAYVAFTSVLAAHMYAIKKKAVIPRNAMTSLHVMMGVVTLQATLGILTILYLVPISLASIHQAGALALLTSSLVFASQLRKPRAPMRNVIITLPHSSKVTSGKILSEASKLASKPL", "length": 486 }, "evidence": [ { "id": "RGD:1312043", "url": "https://alliancegenome.org/gene/RGD:1312043#orthology", "database": "AGR" }, { "id": "MGI:1920112", "url": "https://alliancegenome.org/gene/MGI:1920112#orthology", "database": "AGR" }, { "id": "HGNC:2263", "url": "https://alliancegenome.org/gene/HGNC:2263#orthology", "database": "AGR" }, { "id": "FB:FBgn0034938", "url": "https://alliancegenome.org/gene/FB:FBgn0034938#orthology", "database": "AGR" }, { "id": "SGD:S000000943", "url": "https://alliancegenome.org/gene/SGD:S000000943#orthology", "database": "AGR" }, { "id": "Q9W1F5", "url": "https://omabrowser.org/oma/group/Q9W1F5/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q08DG6-1", "protein_name": "Heme A synthase COX15", "gene_name": "COX15", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQRLLFTPLTAFLGSPCLRLLVPRVAPRTQCGCSCGIRRPLRPGQYSTISDVALQPGRSTVSLPSKAAERVVGRWLLVCSGTVAGAVILGGVTRLTESGLSMVDWHLIKEMKPPTSKEEWEAEFQKYQQFPEFKILNHDMTLAEFKFIWYMEYSHRMWGRLVGLAYILPAAYFWKKGWLTRGLKGRVLALCGLVCFQGLLGWYMVKSGLEEKPDSHDIPRVSQYRLAAHLGSALVLYCASLWTSLSLLLPQHKLTETRQLLRLRRFAHGTAGLVFLTALSGAFVAGLDAGLVYNSFPKMGESWIPEDLFTFSPLLRNVFENPTMVQFDHRVLGIASVTAVTVLYFLSRRIPLPRRTKIAATTLLALAYTQVGLGISTLLMYVPTPLAATHQSGSLALLSVALWLMNELRRVPK", "length": 413 }, "evidence": [ { "id": "Q9W1F5", "url": "https://omabrowser.org/oma/group/Q9W1F5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q7KZN9-1", "protein_name": "Heme A synthase COX15", "gene_name": "COX15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQRLLFPPLRALKGRQYLPLLAPRAAPRAQCDCIRRPLRPGQYSTISEVALQSGRGTVSLPSKAAERVVGRWLLVCSGTVAGAVILGGVTRLTESGLSMVDWHLIKEMKPPTSQEEWEAEFQRYQQFPEFKILNHDMTLTEFKFIWYMEYSHRMWGRLVGLVYILPAAYFWRKGWLSRGMKGRVLALCGLVCFQGLLGWYMVKSGLEEKSDSHDIPRVSQYRLAAHLGSALVLYCASLWTSLSLLLPPHKLPETHQLLQLRRFAHGTAGLVFLTALSGAFVAGLDAGLVYNSFPKMGESWIPEDLFTFSPILRNVFENPTMVQFDHRILGITSVTAITVLYFLSRRIPLPRRTKMAAVTLLALAYTQVGLGISTLLMYVPTPLAATHQSGSLALLTGALWLMNELRRVPK", "length": 410 }, "evidence": [ { "id": "RGD:1312043", "url": "https://alliancegenome.org/gene/RGD:1312043#orthology", "database": "AGR" }, { "id": "MGI:1920112", "url": "https://alliancegenome.org/gene/MGI:1920112#orthology", "database": "AGR" }, { "id": "HGNC:2263", "url": "https://alliancegenome.org/gene/HGNC:2263#orthology", "database": "AGR" }, { "id": "FB:FBgn0034938", "url": "https://alliancegenome.org/gene/FB:FBgn0034938#orthology", "database": "AGR" }, { "id": "SGD:S000000943", "url": "https://alliancegenome.org/gene/SGD:S000000943#orthology", "database": "AGR" }, { "id": "Q9W1F5", "url": "https://omabrowser.org/oma/group/Q9W1F5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BJ03-1", "protein_name": "Heme A synthase COX15", "gene_name": "Cox15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQRLLLPSLRALTGSRNVGLLVPRVASRTQCGSSCGSQRPLRPGQYSTITEVALQSGKGTVSLPSRAAERAVGRWLLVCSGTVAGAVILGGVTRLTESGLSMVDWHLIKEMKPPTSQEEWEAEFQKYQQFPEFKILNHDMTLAEFKFIWYMEYSHRMWGRAVGLAYILPAAYFWRKGWLNRGMKGRVLALCGLVCFQGLLGWYMVKSGLEEKPESYDIPRVSQYRLAAHLGSALVLYCASLWTSLSLLLPQHKLPETRQLLWLRRFAGGTAGLVFLTALSGAFVAGLDAGLVYNSFPKMGESWIPEDLLTFSPVLKNVFENPTMVQFDHRLLGVTSVTAITVLYFLSRRIPLPRRTKMAAVTLLALAYAQVALGISTLLMYVPTPLAATHQSGSLALLSGALWLMNELRRVPK", "length": 413 }, "evidence": [ { "id": "RGD:1312043", "url": "https://alliancegenome.org/gene/RGD:1312043#orthology", "database": "AGR" }, { "id": "MGI:1920112", "url": "https://alliancegenome.org/gene/MGI:1920112#orthology", "database": "AGR" }, { "id": "HGNC:2263", "url": "https://alliancegenome.org/gene/HGNC:2263#orthology", "database": "AGR" }, { "id": "FB:FBgn0034938", "url": "https://alliancegenome.org/gene/FB:FBgn0034938#orthology", "database": "AGR" }, { "id": "SGD:S000000943", "url": "https://alliancegenome.org/gene/SGD:S000000943#orthology", "database": "AGR" }, { "id": "Q9W1F5", "url": "https://omabrowser.org/oma/group/Q9W1F5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9FKT8-1", "protein_name": "Heme A synthase COX15", "gene_name": "COX15", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MFRAVGSALKRNKEAFNGIARGFTTSSHRVFTSNITAASVTSASSSPLAGNSFYGLRSLLKGQNASMFRRMSTVASISSESKEGLKLLVTGGPQAQKWVGIWLFGSAAWVFSMVVLGGVTRLTRSGLSMTDWKFTGEFPPLSDEAWAKEFEKYKQSPEYKRVNKGMNLEDFKFIYWMEYAHRMWGRGLGIMFALPFSYFLRKGYITLRLGVQLSGLFALGAGQGFIGWWMVKSGLEEPPSEYSQPRVSPYRLAAHLTSAFAIYCGLFWTALSVVMPEPPAESLAWVRGAAKVKKLALPVSLIVGITAISGAFVAGNDAGRAFNTFPKMGDTWIPDNIFEMKPLLRNFFENTATVQLDHRLLATTTLIAIGTMWWFTRKLDIHPAVKALIGSTVGMTAVQVTLGVSTLLSYVPVSLGSAHQAGALTLLTLMLLLNHTLRRPSPSLLKSLPQVAKSNFS", "length": 457 }, "evidence": [ { "id": "Q9W1F5", "url": "https://omabrowser.org/oma/group/Q9W1F5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q9W1F5", "url": "https://www.uniprot.org/uniprotkb/Q9W1F5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9W1F5", "url": "https://www.uniprot.org/uniprotkb/Q9W1F5" } ], "pmid": "" }, { "name": "heme A synthase activity", "id": "GO:0120547", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120547", "evidence": [ { "database": "UniProtKB", "id": "Q9W1F5", "url": "https://www.uniprot.org/uniprotkb/Q9W1F5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "heme A biosynthetic process", "id": "GO:0006784", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006784", "evidence": [ { "database": "UniProtKB", "id": "Q9W1F5", "url": "https://www.uniprot.org/uniprotkb/Q9W1F5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 114, "end_pos": 116, "annotation": "n_glycosylation_sequon" }, { "start_pos": 294, "end_pos": 296, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "63388", "name": "", "equation": "Fe(II)-heme o + 2 A + H2O = Fe(II)-heme a + 2 AH2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "63388", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/63388" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 114, "end_pos": 116 }, { "start_pos": 294, "end_pos": 296 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": 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"publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9W1F7-1", "uniprot_ac": "Q9W1F7", "uniprot_id": "Q9W1F7_DROME", "mass": { "chemical_mass": 40532.0, "monoisotopic_mass": 40532.0 }, "refseq": { "ac": "NP_001261161", "name": "stomatin like 2, isoform B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261161" }, "gene_names": [ { "name": "Stoml2", "type": "recommended", "evidence": [ { "id": "Q9W1F7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W1F7" } ] }, { "name": "CG2970", "type": "synonym", "evidence": [ { "id": "NP_001261161", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261161" }, { "id": "Q9W1F7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W1F7" } ] }, { "name": "Dmel\\CG2970", "type": "synonym", "evidence": [ { "id": "NP_001261161", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261161" }, { "id": "Q9W1F7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W1F7" } ] }, { "name": "Dmel_CG2970", "type": "synonym", "evidence": [ { "id": "Q9W1F7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W1F7" } ] }, { "name": "SD03319p", "type": "synonym", "evidence": [ { "id": "NP_001261161", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261161" }, { "id": "Q9W1F7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W1F7" } ] }, { "name": "Stoml2", "type": "synonym", "evidence": [ { "id": "NP_001261161", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261161" } ] }, { "name": "dSLP-2", "type": "synonym", "evidence": [ { "id": "NP_001261161", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261161" }, { "id": "Q9W1F7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W1F7" } ] }, { "name": "dmSTOML2", "type": "synonym", "evidence": [ { "id": "NP_001261161", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261161" }, { "id": "Q9W1F7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W1F7" } ] } ], "protein_names": [ { "name": "CG2970-PB", "type": "synonym", "evidence": [ { "id": "NP_001261161", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261161" } ] }, { "name": "Stomatin like 2, isoform A", "type": "synonym", "evidence": [ { "id": "Q9W1F7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W1F7/entry#names_and_taxonomy" } ] }, { "name": "Stomatin like 2, isoform B", "type": "synonym", "evidence": [ { "id": "Q9W1F7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W1F7/entry#names_and_taxonomy" } ] }, { "name": "Stoml2-PB", "type": "synonym", "evidence": [ { "id": "NP_001261161", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261161" } ] }, { "name": "stomatin like 2, isoform B", "type": "synonym", "evidence": [ { "id": "NP_001261161", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261161" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W1F7", "url": "https://www.uniprot.org/uniprotkb/Q9W1F7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Stoml2", "url": "https://www.uniprot.org/uniprotkb/Q9W1F7", "locus": { "chromosome": "2R", "start_pos": 23952459, "end_pos": 23949201, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0034936", "url": "https://www.ensemblgenomes.org/id/FBgn0034936" } ] } } ], "crossref": [ { "id": "FB:FBgn0034936", "url": "https://alliancegenome.org/gene/FB:FBgn0034936", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0034936", "url": "https://bgee.org/?page=gene&gene_id=FBgn0034936", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08829", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08829", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0034936", "url": "https://flybase.org/reports/FBgn0034936", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "37807", "url": "https://www.ncbi.nlm.nih.gov/gene/37807", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001107", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001107", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001972", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001972", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032435", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032435", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036013", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036013", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050710", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050710", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG2970", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG2970", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YLQMLPK", "url": "https://omabrowser.org/oma/group/YLQMLPK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W1F7", "url": "https://www.orthodb.org/?gene=Q9W1F7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43327", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43327", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43327:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43327:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01145", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01145", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16200", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16200", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001261161", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261161", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W1F7", "url": "https://www.uniprot.org/uniprotkb/Q9W1F7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W1F7-1", "url": "https://www.uniprot.org/uniprotkb/Q9W1F7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRFLLNKRFVPSLVQQDFLLAGSWIPSQSRRGKASTPINMCVMFVPQQEAWVVERMGRFHRILDPGLNILVPVADKIKYVQSLKEIAIDVPKQSAITSDNVTLSIDGVLYLRIIDPYKASYGVEDPEFAITQLAQTTMRSELGKMSMDKVFRERESLNVSIVDSINKASEAWGIACLRYEIRDIRLPTRVHEAMQMQVEAERRKRAAILESEGVREAEINIAEGKRKSRILASEAERQEHINKASGEAAAIIAVADARARSLLAIAKSLSHLDGQNAASLTLAEQYIGAFKKLAKTNNTMILPSNPGDVNGFVAQALAVYNHVSNSNQATKSSENVKGVGACLNAKSVEYKELQEDKSSVKMNIE", "length": 366, "header": "tr|Q9W1F7-1|Q9W1F7_DROME Isoform 1 of Stomatin like 2, isoform B OS=Drosophila melanogaster OX=7227 GN=Stoml2 PE=1 SV=2 CANONICAL=Q9W1F7-1" }, "isoforms": [ { "isoform_ac": "Q9W1F7-1", "url": "https://www.uniprot.org/uniprotkb/Q9W1F7/entry#Q9W1F7-1", "sequence": { "sequence": "MSRFLLNKRFVPSLVQQDFLLAGSWIPSQSRRGKASTPINMCVMFVPQQEAWVVERMGRFHRILDPGLNILVPVADKIKYVQSLKEIAIDVPKQSAITSDNVTLSIDGVLYLRIIDPYKASYGVEDPEFAITQLAQTTMRSELGKMSMDKVFRERESLNVSIVDSINKASEAWGIACLRYEIRDIRLPTRVHEAMQMQVEAERRKRAAILESEGVREAEINIAEGKRKSRILASEAERQEHINKASGEAAAIIAVADARARSLLAIAKSLSHLDGQNAASLTLAEQYIGAFKKLAKTNNTMILPSNPGDVNGFVAQALAVYNHVSNSNQATKSSENVKGVGACLNAKSVEYKELQEDKSSVKMNIE", "length": 366, "header": "tr|Q9W1F7-1|Q9W1F7_DROME Isoform 1 of Stomatin like 2, isoform B OS=Drosophila melanogaster OX=7227 GN=Stoml2 PE=1 SV=2 CANONICAL=Q9W1F7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W1F7", "url": "https://www.uniprot.org/uniprotkb/Q9W1F7" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W1F7", "url": "https://www.uniprot.org/uniprotkb/Q9W1F7" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1F7", "url": "https://www.uniprot.org/uniprotkb/Q9W1F7" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1F7", "url": "https://www.uniprot.org/uniprotkb/Q9W1F7" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W1F7", "url": "https://www.uniprot.org/uniprotkb/Q9W1F7" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W1F7", "url": "https://www.uniprot.org/uniprotkb/Q9W1F7" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W1F7", "url": "https://www.uniprot.org/uniprotkb/Q9W1F7" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1F7", "url": "https://www.uniprot.org/uniprotkb/Q9W1F7" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1F7", "url": "https://www.uniprot.org/uniprotkb/Q9W1F7" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W1F7", "url": "https://www.uniprot.org/uniprotkb/Q9W1F7" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W1F7", "url": "https://www.uniprot.org/uniprotkb/Q9W1F7" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG2970", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG2970", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1W169-1", "protein_name": "Stomatin-like protein 2, mitochondrial", "gene_name": "STOML2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLARAARGTGALLLRGSVQASGRAPRRSSSGLPRNTVVLFVPQQEAWVVERMGRFHRILEPGLNILIPVLDRIRYVQSLKEIVINVPEQSAVTLDNVTLQIDGVLYLRIMDPYKASYGVEDPEYAVTQLAQTTMRSELGKLSLDKVFRERESLNASIVDAINQAADCWGIRCLRYEIKDIHVPPRVKESMQMQVEAERRKRATVLESEGTRESAINVAEGKKQAQILASEAEKAEQINQAAGEASAVLAKAKAKAEAIRILAAALTQHNGDAAASLTVAEQYVSAFSKLAKDSNTILLPSNPGDVTSMVAQAMGVYGALTKAPVPGPQDSVSSRSSRDVQGTDASLDEELDRVKLS", "length": 356 }, "evidence": [ { "id": "Q9W1F7", "url": "https://omabrowser.org/oma/group/Q9W1F7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0YBI3-1", "protein_name": "Stomatin-like protein 2, mitochondrial", "gene_name": "STOML2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLAQAARRAGPGLLRRAPVVKQPAWLAPAPQRLNSGLPVNIGVLFVPQQEAWVVERMGKFHRILEPGLNFLIPLLDRIRYVQSLKEIVINVPEQSAVTLDNVTLQIDGVLYLRVMDPYKASYGVEDPEYAVTQLAQTTMRSELGKLSLDRVFRERESLNANIVDAINQASDCWGIRCLRYEIKDIHVPPRVKESMQMQVEAERRKRATVLESEGTRESAINVAEGQKQAQILASEAEKAEQINKAAGEANAMLVRAKAKAEAIQLLAAALAQQHGSAAASLSVAEQYVSAFSKLAKDSNTVLLPTNTGDVTHMVAQALGIYTTLTKTQAVKTRDELPPAHGDPQIPSTEMLKSEQVTSS", "length": 359 }, "evidence": [ { "id": "Q9W1F7", "url": "https://omabrowser.org/oma/group/Q9W1F7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q4FZT0-1", "protein_name": "Stomatin-like protein 2, mitochondrial", "gene_name": "Stoml2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"MDAPAEGHVDPESCNEIEDEKSGSDCQSMPAYMNSVMRRQYLQQMVKMLPAPVQNRIVFLKNLQLQHLNIEAQFFEDVYKLEQKYQVQYQPLFDKRREIIEGKVDPAEEKPQWKEPESSTDNEADAEHFREALSSLKSIPKDAKGIPGFWLTVFRNTAIMSEMVQPHDEPAIRKLIDISIKYDNGHSYTLEFHFDKNEYFSNSVLTKQYVLKSTVDPNDPFAFEGPEIYKCTGCTINWEKKMNLTVKTIRKKQKHKERGAVRTIVKQVPTDSFFNFFSPPEVPSDQEEVDDDSQQILATDFEIGHFLRARIIPKAVLYYTGDIVDDEDDEDEEEYDENEEDEYDDDDAPPPKGPKSAGIKKQSPNDCPNQ", "length": 370, "header": "tr|Q9W1G7-1|Q9W1G7_DROME Isoform 1 of Nucleosome assembly protein 1, isoform B OS=Drosophila melanogaster OX=7227 GN=Nap1 PE=1 SV=1 CANONICAL=Q9W1G7-1" }, "isoforms": [ { "isoform_ac": "Q9W1G7-1", "url": "https://www.uniprot.org/uniprotkb/Q9W1G7/entry#Q9W1G7-1", "sequence": { "sequence": "MDAPAEGHVDPESCNEIEDEKSGSDCQSMPAYMNSVMRRQYLQQMVKMLPAPVQNRIVFLKNLQLQHLNIEAQFFEDVYKLEQKYQVQYQPLFDKRREIIEGKVDPAEEKPQWKEPESSTDNEADAEHFREALSSLKSIPKDAKGIPGFWLTVFRNTAIMSEMVQPHDEPAIRKLIDISIKYDNGHSYTLEFHFDKNEYFSNSVLTKQYVLKSTVDPNDPFAFEGPEIYKCTGCTINWEKKMNLTVKTIRKKQKHKERGAVRTIVKQVPTDSFFNFFSPPEVPSDQEEVDDDSQQILATDFEIGHFLRARIIPKAVLYYTGDIVDDEDDEDEEEYDENEEDEYDDDDAPPPKGPKSAGIKKQSPNDCPNQ", "length": 370, "header": "tr|Q9W1G7-1|Q9W1G7_DROME Isoform 1 of Nucleosome assembly protein 1, isoform B OS=Drosophila melanogaster OX=7227 GN=Nap1 PE=1 SV=1 CANONICAL=Q9W1G7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W1G7", "url": "https://www.uniprot.org/uniprotkb/Q9W1G7" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W1G7", "url": "https://www.uniprot.org/uniprotkb/Q9W1G7" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1G7", "url": "https://www.uniprot.org/uniprotkb/Q9W1G7" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1G7", "url": "https://www.uniprot.org/uniprotkb/Q9W1G7" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W1G7", "url": "https://www.uniprot.org/uniprotkb/Q9W1G7" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W1G7", "url": "https://www.uniprot.org/uniprotkb/Q9W1G7" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W1G7", "url": "https://www.uniprot.org/uniprotkb/Q9W1G7" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1G7", "url": "https://www.uniprot.org/uniprotkb/Q9W1G7" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1G7", "url": "https://www.uniprot.org/uniprotkb/Q9W1G7" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W1G7", "url": "https://www.uniprot.org/uniprotkb/Q9W1G7" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W1G7", "url": "https://www.uniprot.org/uniprotkb/Q9W1G7" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG5330", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG5330", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A2R8Q4J7-1", "protein_name": "Nucleosome assembly protein 1-like 4a isoform X1", "gene_name": "nap1l4a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDKKNEKGEARGKGGTKPDKPEAFLQVERVPNFNLLPKNVKRRVYALKRLQLQSGNIEAKFYEEVHELERKYAGLYQPILDKRREIVTGAVEPTDEECEWHSDKEEDELADDLQKKAALEEKQADSASAVDPKGIPDFWLTIFKHVDMLGEMLQEHDEPILKHLQDVTVKFSEPGQPMSFTLEFHFEPNSYFSNTVLTKVYKMKSEPDAADPFSFEGPEIVDCEGCKIDWHKGKDVTVKIVKKKQKHKGRGTIRTVSKEIPQDSFFNFFNPVKASPDGMDEDLDFTLATDFEIGHFFRERVIPRAVLYFTGEALEDDESFEEEDLEEGEEEDLDEEGEEEEEGDFDPTKDPPPAECKQQ", "length": 359 }, "evidence": [ { "id": "MGI:1316687", "url": "https://alliancegenome.org/gene/MGI:1316687#orthology", "database": "AGR" }, { "id": "HGNC:7640", "url": "https://alliancegenome.org/gene/HGNC:7640#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M2BJ06-1", "protein_name": "Nucleosome assembly protein 1-like 1 isoform X1", "gene_name": "nap1l1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADLDNKDQAEMDPADMEDVEEEEEDAGEDNSKARQLTRQMMQNPQILAALQERLDGLVGSPSGYMESLPKVVKRRVNALKNLQVKCAHIEAKFYEEVHELERKYAALYQPLFDKRSEIVRAAYEPTDEECEWKQDEEEELTEEMKEKAKVEEEKKDEEKEDPKGIPEFWLTVFKNVDLLSEMLQEHDEPILKHLQDIKVKFSDAGQPMSFTLEFHFEPNDFFTQTILTKTYKMRSEPDESDPFSFDGPEIMGCTGCTIDWTKGKNVTLKTIKKKQKHKGRGTVRTVTKTVPNDSFFNFFSPPEVPESGELDEDSEAVLAADFEIGHFIRERIVPRAVLYFTGEAIEDDDDDYDEEGEEADDEEGEEEADEENDPDYEPKKDANPPEECKQQ", "length": 392 }, "evidence": [ { "id": "MGI:1855693", "url": "https://alliancegenome.org/gene/MGI:1855693#orthology", "database": "AGR" }, { "id": "HGNC:7637", "url": "https://alliancegenome.org/gene/HGNC:7637#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030516-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030516-2#orthology", "database": "AGR" }, { "id": "FB:FBgn0015268", "url": "https://alliancegenome.org/gene/FB:FBgn0015268#orthology", "database": "AGR" }, { "id": "RGD:1560617", "url": "https://alliancegenome.org/gene/RGD:1560617#orthology", "database": "AGR" }, { "id": "RGD:71094", "url": "https://alliancegenome.org/gene/RGD:71094#orthology", "database": "AGR" }, { "id": "SGD:S000001756", "url": "https://alliancegenome.org/gene/SGD:S000001756#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58FZ21-1", "protein_name": "Nucleosome assembly protein 1-like 4b isoform X1", "gene_name": "nap1l4b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTLSITAEYLSCSIKMEADNEAKGKVSDQAMQNPQALAALQDKLDSVSHSASIMDSLPKSVKRRVNALRNLQVNSTHIEAKFYKEVHELERKYSALYQPLFDKRRKVVSGEVEPTDEECEWQSDHEDEAALAEDLKKKAAIEEKTEDANEEKPKGIPEFWLTIFRSVDMLSDMLQEHDEPILKHLHDIKVIFSGPDQPMSFTLEFHFEPNEYFTNTVLTKVYKMKSEPDADDPFSFEGPEIIDCEGCEIDWQKGKDVTVKTIKKKQKHKGRGTARVITKQVPNDSFFNFFNPIKVSPDKELDEDSEYTLATDFEIGHFFRERIVPRAVLYFTGEALEDDESFEEEELDEGEEEDQDDEEEEEEEEEGDSKTGDPQPAECKQQ", "length": 382 }, "evidence": [ { "id": "MGI:1316687", "url": "https://alliancegenome.org/gene/MGI:1316687#orthology", "database": "AGR" }, { "id": "HGNC:7640", "url": "https://alliancegenome.org/gene/HGNC:7640#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-168", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-168#orthology", "database": "AGR" }, { "id": "FB:FBgn0015268", "url": "https://alliancegenome.org/gene/FB:FBgn0015268#orthology", "database": "AGR" }, { "id": "RGD:1305391", "url": "https://alliancegenome.org/gene/RGD:1305391#orthology", "database": "AGR" }, { "id": "SGD:S000001756", "url": "https://alliancegenome.org/gene/SGD:S000001756#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D4AEJ0-1", "protein_name": "Nucleosome assembly protein 1 like 6", "gene_name": "Nap1l6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADIDNKKESELDQDLEDVEKVEEEETGEETKVKARQLTVQMMQNPQILAALQARLGSRVDTPTGYTESLPKVVKRRVNALKNLLVKCAQIEAKFDEDVHDLERKYAVLCQPLFDKRFEIINAIYEPTEEECEWKPDEEDEVSEELKEKAMIEDEKKDEEKEDPKGIPEFWLTDFKNVDLLSDMVQEHDEPILKPLKDTKVKFSDPGQPISFILEFHFEPNEYFTNEMLTKTYRMRSEPDDSDPLSFDGPEIMGCTGCQIDWKKGKNVTLKTIKKKQKHKGHGGTVRTVTKTVSNDSFFNFFAPPEIPENGDLDDDAEAILAADFEIGHFLCEHIIPRSVLFFTGEDIEDDGDDYDEEGEDADEGYQLFEQVKSCSKLFQCWLQ", "length": 384 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-030516-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030516-2#orthology", "database": "AGR" }, { "id": "FB:FBgn0015268", "url": "https://alliancegenome.org/gene/FB:FBgn0015268#orthology", "database": "AGR" }, { "id": "RGD:1560617", "url": "https://alliancegenome.org/gene/RGD:1560617#orthology", "database": "AGR" }, { "id": "SGD:S000001756", "url": "https://alliancegenome.org/gene/SGD:S000001756#orthology", "database": "AGR" }, { "id": "Q9W1G7", "url": "https://omabrowser.org/oma/group/Q9W1G7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P25293-1", "protein_name": "Nucleosome assembly protein", "gene_name": "NAP1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSDPIRTKPKSSMQIDNAPTPHNTPASVLNPSYLKNGNPVRAQAQEQDDKIGTINEEDILANQPLLLQSIQDRLGSLVGQDSGYVGGLPKNVKEKLLSLKTLQSELFEVEKEFQVEMFELENKFLQKYKPIWEQRSRIISGQEQPKPEQIAKGQEIVESLNETELLVDEEEKAQNDSEEEQVKGIPSFWLTALENLPIVCDTITDRDAEVLEYLQDIGLEYLTDGRPGFKLLFRFDSSANPFFTNDILCKTYFYQKELGYSGDFIYDHAEGCEISWKDNAHNVTVDLEMRKQRNKTTKQVRTIEKITPIESFFNFFDPPKIQNEDQDEELEEDLEERLALDYSIGEQLKDKLIPRAVDWFTGAALEFEFEEDEEEADEDEDEEEDDDHGLEDDDGESAEEQDDFAGRPEQAPECKQS", "length": 417 }, "evidence": [ { "id": "MGI:106654", "url": "https://alliancegenome.org/gene/MGI:106654#orthology", "database": "AGR" }, { "id": "MGI:1316687", "url": "https://alliancegenome.org/gene/MGI:1316687#orthology", "database": "AGR" }, { "id": "MGI:1855693", "url": "https://alliancegenome.org/gene/MGI:1855693#orthology", "database": "AGR" }, { "id": "MGI:1859565", "url": "https://alliancegenome.org/gene/MGI:1859565#orthology", "database": "AGR" }, { "id": "HGNC:7639", "url": "https://alliancegenome.org/gene/HGNC:7639#orthology", "database": "AGR" }, { "id": "HGNC:7637", "url": "https://alliancegenome.org/gene/HGNC:7637#orthology", "database": "AGR" }, { "id": "HGNC:7640", "url": "https://alliancegenome.org/gene/HGNC:7640#orthology", "database": "AGR" }, { "id": "HGNC:7638", "url": "https://alliancegenome.org/gene/HGNC:7638#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030516-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030516-2#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-168", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-168#orthology", "database": "AGR" }, { "id": "FB:FBgn0015268", "url": "https://alliancegenome.org/gene/FB:FBgn0015268#orthology", "database": "AGR" }, { "id": "RGD:620990", "url": "https://alliancegenome.org/gene/RGD:620990#orthology", "database": "AGR" }, { "id": "RGD:1560617", "url": "https://alliancegenome.org/gene/RGD:1560617#orthology", "database": "AGR" }, { "id": "RGD:71094", "url": "https://alliancegenome.org/gene/RGD:71094#orthology", "database": "AGR" }, { "id": "RGD:1305391", "url": "https://alliancegenome.org/gene/RGD:1305391#orthology", "database": "AGR" }, { "id": "SGD:S000001756", "url": "https://alliancegenome.org/gene/SGD:S000001756#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P28656-1", "protein_name": "Nucleosome assembly protein 1-like 1", "gene_name": "Nap1l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADIDNKEQSELDQDLEDVEEVEEEETGEETKIKARQLTVQMMQNPQILAALQERLDGLVDTPTGYIESLPKVVKRRVNALKNLQVKCAQIEAKFYEEVHDLERKYAVLYQPLFDKRFEIINAIYEPTEEECEWKPDEEDEVSEELKEKAKIEDEKKDEEKEDPKGIPEFWLTVFKNVDLLSDMVQEHDEPILKHLKDIKVKFSDAGQPMSFVLEFHFEPNDYFTNEVLTKTYRMRSEPDDSDPFSFDGPEIMGCTGCQIDWKKGKNVTLKTIKKKQKHKGRGTVRTVTKTVSNDSFFNFFAPPEVPENGDLDDDAEAILAADFEIGHFLRERIIPRSVLYFTGEAIEDDDDDYDEEGEEADEEGEEEGDEENDPDYDPKKDQNPAECKQQ", "length": 391 }, "evidence": [ { "id": "MGI:1855693", "url": "https://alliancegenome.org/gene/MGI:1855693#orthology", "database": "AGR" }, { "id": "HGNC:7637", "url": "https://alliancegenome.org/gene/HGNC:7637#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030516-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030516-2#orthology", "database": "AGR" }, { "id": "FB:FBgn0015268", "url": "https://alliancegenome.org/gene/FB:FBgn0015268#orthology", "database": "AGR" }, { "id": "RGD:71094", "url": "https://alliancegenome.org/gene/RGD:71094#orthology", "database": "AGR" }, { "id": "SGD:S000001756", "url": "https://alliancegenome.org/gene/SGD:S000001756#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P51860-1", "protein_name": "Nucleosome assembly protein 1-like 2", "gene_name": "Nap1l2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAESVDHKELSESNQEELGSQVMAEGPGESQDRSEGVSIEPGDGGQHGEETVAAGVGEEGKGEEAAAGSGEDAGKCGGTDEDSDSDRPKGLIGYLLDTDFVESLPVKVKCRVLALKKLQTRAAHLESKFLREFHDIERKFAEMYQPLLEKRRQIINAVYEPTEEECEYKSDCEDYFEEEMDEEEETNGNEDGMVHEYVDEDDGYEDCYYDYDDEEEEEEEDDSAGATGGEEVNEEDPKGIPDFWLTVLKNVEALTPMIKKYDEPILKLLTDIKVKLSDPGEPLSFTLEFHFKPNEYFKNELLTKTYVLKSKLACYDPHPYRGTAIEYATGCDIDWNEGKNVTLRTIKKKQRHRVWGTVRTVTEDFPKDSFFNFFSPHGISLNGGDENDDFLLGHNLRTYIIPRSVLFFSGDALESQQEGVVREVNDEIYDKIIYDDWMAAIEEVKACCKNLEALVEDIDR", "length": 460 }, "evidence": [ { "id": "MGI:106654", "url": "https://alliancegenome.org/gene/MGI:106654#orthology", "database": "AGR" }, { "id": "HGNC:7638", "url": "https://alliancegenome.org/gene/HGNC:7638#orthology", "database": "AGR" }, { "id": "FB:FBgn0015268", "url": "https://alliancegenome.org/gene/FB:FBgn0015268#orthology", "database": "AGR" }, { "id": "SGD:S000001756", "url": "https://alliancegenome.org/gene/SGD:S000001756#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P55209-1", "protein_name": "Nucleosome assembly protein 1-like 1", "gene_name": "NAP1L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADIDNKEQSELDQDLDDVEEVEEEETGEETKLKARQLTVQMMQNPQILAALQERLDGLVETPTGYIESLPRVVKRRVNALKNLQVKCAQIEAKFYEEVHDLERKYAVLYQPLFDKRFEIINAIYEPTEEECEWKPDEEDEISEELKEKAKIEDEKKDEEKEDPKGIPEFWLTVFKNVDLLSDMVQEHDEPILKHLKDIKVKFSDAGQPMSFVLEFHFEPNEYFTNEVLTKTYRMRSEPDDSDPFSFDGPEIMGCTGCQIDWKKGKNVTLKTIKKKQKHKGRGTVRTVTKTVSNDSFFNFFAPPEVPESGDLDDDAEAILAADFEIGHFLRERIIPRSVLYFTGEAIEDDDDDYDEEGEEADEEGEEEGDEENDPDYDPKKDQNPAECKQQ", "length": 391 }, "evidence": [ { "id": "MGI:1855693", "url": "https://alliancegenome.org/gene/MGI:1855693#orthology", "database": "AGR" }, { "id": "HGNC:7637", "url": "https://alliancegenome.org/gene/HGNC:7637#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030516-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030516-2#orthology", "database": "AGR" }, { "id": "FB:FBgn0015268", "url": "https://alliancegenome.org/gene/FB:FBgn0015268#orthology", "database": "AGR" }, { "id": "RGD:71094", "url": "https://alliancegenome.org/gene/RGD:71094#orthology", "database": "AGR" }, { "id": "SGD:S000001756", "url": "https://alliancegenome.org/gene/SGD:S000001756#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5U2Z3-1", "protein_name": "Nucleosome assembly protein 1-like 4", "gene_name": "Nap1l4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAENSLSDGGPADSVEAAKNASNTEKLTDQVMQNPQVLAALQERLDNVSHTPSSYIETLPKAVKRRINALKQLQVRCAHIEAKFYEEVHDLERKYAALYQPLFDKRREFITGDVEPTDAESAWHSENEEDDKLAGDMKNKVVIAEKEAAAVEELNPKGIPEFWFTIFRNVDMLSELVQEYDEPILKHLQDIKVKFSDPGQPMSFVLEFHFEPNDYFTNPVLTKTYKMKSEPDKADPFSFEGPEIVDCDGCTIDWKKGKNVTVKTIKKKQKHKGRGTVRTITKQVPNESFFNFFSPLKASGDGESLDEDSEFTLASDFEIGHFFRERIVPRAVLYFTGEAIEDDDNFEEGEEGEEEELEGDEEGEDEDDADVNPKKEPIQPAECKQQ", "length": 386 }, "evidence": [ { "id": "MGI:1316687", "url": "https://alliancegenome.org/gene/MGI:1316687#orthology", "database": "AGR" }, { "id": "HGNC:7640", "url": "https://alliancegenome.org/gene/HGNC:7640#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-168", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-168#orthology", "database": "AGR" }, { "id": "FB:FBgn0015268", "url": "https://alliancegenome.org/gene/FB:FBgn0015268#orthology", "database": "AGR" }, { "id": "RGD:1305391", "url": "https://alliancegenome.org/gene/RGD:1305391#orthology", "database": "AGR" }, { "id": "SGD:S000001756", "url": "https://alliancegenome.org/gene/SGD:S000001756#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q78ZA7-1", "protein_name": "Nucleosome assembly protein 1-like 4", "gene_name": "Nap1l4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAENSLSDGGPADSVEAAKNASNTEKLTDQVMQNPQVLAALQERLDNVSHTPSSYIETLPKAVKRRINALKQLQVRCAHIEAKFYEEVHDLERKYAALYQPLFDKRREFITGDVEPTDAESAWHSENEEEDKLAGDMKNKVVIAEKEAATVEELNPKGIPEFWFTIFRNVDMLSELVQEYDEPILKHLQDIKVKFSDPGQPMSFVLEFHFEPNDYFTNPVLTKTYKMKSEPDKADPFSFEGPEIVDCDGCTIDWKKGKNVTVKTIKKKQKHKGRGTVRTITKQVPNESFFNFFSPLKASGDGESLDEDSEFTLASDFEIGHFFRERIVPRAVLYFTGEAIEDDDNFEEGEEGEEEELEGDEEGEDEDDADVNPKV", "length": 375 }, "evidence": [ { "id": "MGI:1316687", "url": "https://alliancegenome.org/gene/MGI:1316687#orthology", "database": "AGR" }, { "id": "HGNC:7640", "url": "https://alliancegenome.org/gene/HGNC:7640#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-168", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-168#orthology", "database": "AGR" }, { "id": "FB:FBgn0015268", "url": "https://alliancegenome.org/gene/FB:FBgn0015268#orthology", "database": "AGR" }, { "id": "RGD:1305391", "url": "https://alliancegenome.org/gene/RGD:1305391#orthology", "database": "AGR" }, { "id": "SGD:S000001756", "url": "https://alliancegenome.org/gene/SGD:S000001756#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q794H2-1", "protein_name": "Nucleosome assembly protein 1-like 3", "gene_name": "Nap1l3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEADPKMVTEPGAHGVAEEAMASTACDSGDESDSNSSSSTNSCSSSGSSSSGSSSSSSSSSSSSSSSSSSSSGSSGSSSNGSHLNRKKRVPEPSRRAQRRPSGKLFLDKLPQAVRNRVQALRNIQNECDKVDTLFLRAIHDLERKYAELNKPLYDKRFQIINAEYEPTEEECEWNSEEEFSGDEEMQDDTPNEMPPLEGEEEEESCNEKAEVKEEGTHVPEEVPEAKVEEEEAPKETPEVKTEEKDIPKEGAEEKAEEQESSKEIPEVKGEEKADSTDCIDIAPEEKEDVKEVTQANTENKDQPTEEFTPRAPAREAQKRVPETRPEEGVNIKRARKGKPKKEDPKGIPDYWLTVLKNVDKLGPMIQKCDEPILKFLSDVSLKFSNPGQPIGYTFEFHFLPNPYFRNELLMKTYIIRSKPDHYDPFFAWGWEIEECKGCKIDWRRGKDVTVTTTRSRPGITGEIEVQPRVVPNASFFNFFSPPEIPLIGKLEPREDAILDEDFEIGQILHDNVILKSIYYFTGEINDPYYHDFRDYGNRKYYK", "length": 544 }, "evidence": [ { "id": "MGI:1859565", "url": "https://alliancegenome.org/gene/MGI:1859565#orthology", "database": "AGR" }, { "id": "HGNC:7639", "url": "https://alliancegenome.org/gene/HGNC:7639#orthology", "database": "AGR" }, { "id": "FB:FBgn0015268", "url": "https://alliancegenome.org/gene/FB:FBgn0015268#orthology", "database": "AGR" }, { "id": "RGD:620990", "url": "https://alliancegenome.org/gene/RGD:620990#orthology", "database": "AGR" }, { "id": "SGD:S000001756", "url": "https://alliancegenome.org/gene/SGD:S000001756#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7KW25-1", "protein_name": "Nucleosome assembly protein 1-like 4", "gene_name": "Dmel\\CG3708", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MIGMADSAEGVTQEDSHTESRADGISGSLRSLGTYTQESTEPALSPADLPARSRKAFLRHMIGQLAEPVQNRIRALRHNQLQQVRISEQFFREVYELERRFYGQSCALFDARRDILEGSVEPPIQTEKTWPEDPQDALYLDFGNNEELRQLRQKLAPVSPTTLGVPRFWLTVFQNVPLLSELVQDHDEPLLESLMDVRLAYDQDSYMVIFQFRPNSFLHDSSLLLTKRYFLQHSADPEYPFLFEGPEIVRCEGCHIHWRDGSNLTLQTVESRRRNRAHRVTKVMPRESFFRFFAPPQALDLSLADEKTKLILGNDFEVGFLLRTQIVPKAVLFYTGDLVDSLSAASPDSRSLSSEAEQEQVL", "length": 362 }, "evidence": [ { "id": "MGI:106654", "url": "https://alliancegenome.org/gene/MGI:106654#orthology", "database": "AGR" }, { "id": "HGNC:7638", "url": "https://alliancegenome.org/gene/HGNC:7638#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030516-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030516-2#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-168", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-168#orthology", "database": "AGR" }, { "id": "RGD:620990", "url": "https://alliancegenome.org/gene/RGD:620990#orthology", "database": "AGR" }, { "id": "RGD:1560617", "url": "https://alliancegenome.org/gene/RGD:1560617#orthology", "database": "AGR" }, { "id": "SGD:S000001756", "url": "https://alliancegenome.org/gene/SGD:S000001756#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q924R9-1", "protein_name": "Nucleosome assembly protein 1-like 3", "gene_name": "Nap1l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEADPKMVTEPAAQGVAEEAMASSACDSGDESDSNSSSSTTSCGSTGSSSSSSSSSSSSSSSSSGSSGSSSNGSHLHQKKRVPGPSRRAQRRPSGKLFMDKLPQAVRNRVQALRNIQNECDKVDTLFLRAIHDLERKYAELNKPLYDKRFQIINAEYEPTEEECEWNSEEEFSGDEEMQDDTPNEMPPLEGEEEEEIGKENTEVKEEVKDVPEEVPEAKVEEEEAPKETSEVKTEEKEIPKEGPEEKAEEQESSKEFPEVKVEEKTDSTDCIDIAPEEKEDLKDVTQANAEYTDQPTEDSTPRAPVREAQKRVPETRPEERVNIKRARKGKPKKEDPPRGIPDYWLTVLKNVDKLGPMIQKCDEPILKFLSDVSLKFSNPGQPISYTFEFHFLPNPYFRNELLMKTYIIRSKPDHYDPFFAWGWEIEECKGCKIDWRRGKDVTVTTRSRPAITGEIEVQPRVVPNASFFNFFSPPEIPLIGKLEPKEDAILDEDFEIGQILHDNVILKSIYYFTGEINDPYYHDFRDYGNRKYYK", "length": 536 }, "evidence": [ { "id": "MGI:1859565", "url": "https://alliancegenome.org/gene/MGI:1859565#orthology", "database": "AGR" }, { "id": "HGNC:7639", "url": "https://alliancegenome.org/gene/HGNC:7639#orthology", "database": "AGR" }, { "id": "FB:FBgn0015268", "url": "https://alliancegenome.org/gene/FB:FBgn0015268#orthology", "database": "AGR" }, { "id": "RGD:620990", "url": "https://alliancegenome.org/gene/RGD:620990#orthology", "database": "AGR" }, { "id": "SGD:S000001756", "url": "https://alliancegenome.org/gene/SGD:S000001756#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q99457-1", "protein_name": "Nucleosome assembly protein 1-like 3", "gene_name": "NAP1L3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEADFKMVSEPVAHGVAEEEMASSTSDSGEESDSSSSSSSTSDSSSSSSTSGSSSGSGSSSSSSGSTSSRSRLYRKKRVPEPSRRARRAPLGTNFVDRLPQAVRNRVQALRNIQDECDKVDTLFLKAIHDLERKYAELNKPLYDRRFQIINAEYEPTEEECEWNSEDEEFSSDEEVQDNTPSEMPPLEGEEEENPKENPEVKAEEKEVPKEIPEVKDEEKEVPKEIPEVKAEEKADSKDCMEATPEVKEDPKEVPQVKADDKEQPKATEAKARAAVRETHKRVPEERLQDSVDLKRARKGKPKREDPKGIPDYWLIVLKNVDKLGPMIQKYDEPILKFLSDVSLKFSKPGQPVSYTFEFHFLPNPYFRNEVLVKTYIIKAKPDHNDPFFSWGWEIEDCKGCKIDWRRGKDVTVTTTQSRTTATGEIEIQPRVVPNASFFNFFSPPEIPMIGKLEPREDAILDEDFEIGQILHDNVILKSIYYYTGEVNGTYYQFGKHYGNKKYRK", "length": 506 }, "evidence": [ { "id": "MGI:1859565", "url": "https://alliancegenome.org/gene/MGI:1859565#orthology", "database": "AGR" }, { "id": "HGNC:7639", "url": "https://alliancegenome.org/gene/HGNC:7639#orthology", "database": "AGR" }, { "id": "FB:FBgn0015268", "url": "https://alliancegenome.org/gene/FB:FBgn0015268#orthology", "database": "AGR" }, { "id": "RGD:620990", "url": "https://alliancegenome.org/gene/RGD:620990#orthology", "database": "AGR" }, { "id": "SGD:S000001756", "url": "https://alliancegenome.org/gene/SGD:S000001756#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99733-1", "protein_name": "Nucleosome assembly protein 1-like 4", "gene_name": "NAP1L4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADHSFSDGVPSDSVEAAKNASNTEKLTDQVMQNPRVLAALQERLDNVPHTPSSYIETLPKAVKRRINALKQLQVRCAHIEAKFYEEVHDLERKYAALYQPLFDKRREFITGDVEPTDAESEWHSENEEEEKLAGDMKSKVVVTEKAAATAEEPDPKGIPEFWFTIFRNVDMLSELVQEYDEPILKHLQDIKVKFSDPGQPMSFVLEFHFEPNDYFTNSVLTKTYKMKSEPDKADPFSFEGPEIVDCDGCTIDWKKGKNVTVKTIKKKQKHKGRGTVRTITKQVPNESFFNFFNPLKASGDGESLDEDSEFTLASDFEIGHFFRERIVPRAVLYFTGEAIEDDDNFEEGEEGEEEELEGDEEGEDEDDAEINPKV", "length": 375 }, "evidence": [ { "id": "MGI:1316687", "url": "https://alliancegenome.org/gene/MGI:1316687#orthology", "database": "AGR" }, { "id": "HGNC:7640", "url": "https://alliancegenome.org/gene/HGNC:7640#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-168", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-168#orthology", "database": "AGR" }, { "id": "FB:FBgn0015268", "url": "https://alliancegenome.org/gene/FB:FBgn0015268#orthology", "database": "AGR" }, { "id": "RGD:1305391", "url": "https://alliancegenome.org/gene/RGD:1305391#orthology", "database": "AGR" }, { "id": "SGD:S000001756", "url": "https://alliancegenome.org/gene/SGD:S000001756#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9ULW6-1", "protein_name": "Nucleosome assembly protein 1-like 2", "gene_name": "NAP1L2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAESENRKELSESSQEEAGNQIMVEGLGEHLERGEDAAAGLGDDGKCGEEAAAGLGEEGENGEDTAAGSGEDGKKGGDTDEDSEADRPKGLIGYVLDTDFVESLPVKVKYRVLALKKLQTRAANLESKFLREFHDIERKFAEMYQPLLEKRRQIINAIYEPTEEECEYKSDSEDCDDEEMCHEEMYGNEEGMVHEYVDEDDGYEDYYYDYAVEEEEEEEEEDDIEATGEENKEEEDPKGIPDFWLTVLKNVDTLTPLIKKYDEPILKLLTDIKVKLSDPGEPLSFTLEFHFKPNEYFKNELLTKTYVLKSKLAYYDPHPYRGTAIEYSTGCEIDWNEGKNVTLKTIKKKQKHRIWGTIRTVTEDFPKDSFFNFFSPHGITSNGRDGNDDFLLGHNLRTYIIPRSVLFFSGDALESQQEGVVREVNDAIYDKIIYDNWMAAIEEVKACCKNLEALVEDIDR", "length": 460 }, "evidence": [ { "id": "MGI:106654", "url": "https://alliancegenome.org/gene/MGI:106654#orthology", "database": "AGR" }, { "id": "HGNC:7638", "url": "https://alliancegenome.org/gene/HGNC:7638#orthology", "database": "AGR" }, { "id": "FB:FBgn0015268", "url": "https://alliancegenome.org/gene/FB:FBgn0015268#orthology", "database": "AGR" }, { "id": "SGD:S000001756", "url": "https://alliancegenome.org/gene/SGD:S000001756#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VAZ1-1", "protein_name": "Milkah", "gene_name": "mil", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "METVRNRNPPRMKYTAPPKMESDLNFTEKEKKTLTELKQLYLETINLDVALQRDIYNIEKKYEDKHNIIFDKRKKILDEFRKQNHGDVETNQSVPNFWLRVLKASYTEFISKRDEKILECLSDIRSRLYNEPVVKFDIEFHFDPNDYFTNTVLTKTYFLNCLPDPDDPLAYDGAEIYKCEGCVIDWKQTKDQTKTENQEPSFFEFFSPPLLPEDTLDPNYCDVNAMLQNDFEVGFYLKERVIPKAVIFFTGEIADCQSSSGSETESEDTEDESDAEEEDGVDK", "length": 283 }, "evidence": [ { "id": "MGI:106654", "url": "https://alliancegenome.org/gene/MGI:106654#orthology", "database": "AGR" }, { "id": "MGI:1316687", "url": "https://alliancegenome.org/gene/MGI:1316687#orthology", "database": "AGR" }, { "id": "MGI:1855693", "url": "https://alliancegenome.org/gene/MGI:1855693#orthology", "database": "AGR" }, { "id": "MGI:1859565", "url": "https://alliancegenome.org/gene/MGI:1859565#orthology", "database": "AGR" }, { "id": "HGNC:7639", "url": "https://alliancegenome.org/gene/HGNC:7639#orthology", "database": "AGR" }, { "id": "HGNC:7637", "url": "https://alliancegenome.org/gene/HGNC:7637#orthology", "database": "AGR" }, { "id": "HGNC:7640", "url": "https://alliancegenome.org/gene/HGNC:7640#orthology", "database": "AGR" }, { "id": "HGNC:7638", "url": "https://alliancegenome.org/gene/HGNC:7638#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030516-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030516-2#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-168", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-168#orthology", "database": "AGR" }, { "id": "RGD:620990", "url": "https://alliancegenome.org/gene/RGD:620990#orthology", "database": "AGR" }, { "id": "RGD:1560617", "url": "https://alliancegenome.org/gene/RGD:1560617#orthology", "database": "AGR" }, { "id": "SGD:S000001756", "url": "https://alliancegenome.org/gene/SGD:S000001756#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { 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"GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9W1G7", "url": "https://www.uniprot.org/uniprotkb/Q9W1G7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9W1G7", "url": "https://www.uniprot.org/uniprotkb/Q9W1G7" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9W1G7", "url": "https://www.uniprot.org/uniprotkb/Q9W1G7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9W1G7", "url": "https://www.uniprot.org/uniprotkb/Q9W1G7" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "Q9W1G7", "url": "https://www.uniprot.org/uniprotkb/Q9W1G7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "Q9W1G7", "url": "https://www.uniprot.org/uniprotkb/Q9W1G7" } ], "pmid": "" }, { "name": "telomere maintenance", "id": "GO:0000723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000723", "evidence": [ { "database": "UniProtKB", "id": "Q9W1G7", "url": "https://www.uniprot.org/uniprotkb/Q9W1G7" } ], "pmid": "" }, { "name": "nucleosome assembly", "id": "GO:0006334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006334", "evidence": [ { "database": "UniProtKB", "id": "Q9W1G7", "url": "https://www.uniprot.org/uniprotkb/Q9W1G7" } ], "pmid": "" }, { "name": "DNA replication-dependent chromatin assembly", "id": "GO:0006335", "url": 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}, { "name": "BcDNA:SD18780", "type": "synonym", "evidence": [ { "id": "NP_611840", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611840" } ] }, { "name": "CG5569", "type": "synonym", "evidence": [ { "id": "NP_611840", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611840" }, { "id": "Q9W1H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W1H9" } ] }, { "name": "Dmel\\CG5569", "type": "synonym", "evidence": [ { "id": "NP_611840", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611840" } ] }, { "name": "dNDUFAF3", "type": "synonym", "evidence": [ { "id": "NP_611840", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611840" } ] } ], "protein_names": [ { "name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3", "type": "recommended", "evidence": [ { "id": "Q9W1H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W1H9/entry#names_and_taxonomy" } ] }, { "name": "CG5569-PA", "type": "synonym", "evidence": [ { "id": "NP_611840", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611840" } ] }, { "name": "NADH:ubiquinone oxidoreductase complex assembly factor 3", "type": "synonym", "evidence": [ { "id": "Q9W1H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W1H9/entry#names_and_taxonomy" } ] }, { "name": "dNDUFAF3", "type": "synonym", "evidence": [ { "id": "Q9W1H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W1H9/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_611840", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611840" } ] } ], "function": [ { "annotation": "Involved in the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I) (PubMed:34386730). Together with NdufAF4, involved in biogenesis of complex 1 modules N, Q and P-peripheral, but not the P-distal module (PubMed:34386730). Required for recruitment of the complex I assembly factor Timmdc1 to complex 1 assembly intermediates (PubMed:34386730).", "evidence": [ { "database": "UniProtKB", "id": "Q9W1H9", "url": "https://www.uniprot.org/uniprotkb/Q9W1H9#function" }, { "database": "PubMed", "id": "34386730", "url": "https://glygen.org/publication/PubMed/34386730" } ] } ], "disease": [ { "disease_id": "DOID:0112070", "recommended_name": { "id": "DOID:0112070", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0112070", "name": "nuclear type mitochondrial complex I deficiency 18", "description": "A nuclear type mitochondrial complex I deficiency that has_material_basis_in homozygous or compound heterozygous mutation in the NDUFAF3 gene on chromosome 2p21.31." }, "synonyms": [ { "id": "DOID:0112070", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0112070", "name": "MC1DN18", "description": "" }, { "id": "MONDO:0032623", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0032623", "name": "mitochondrial complex I deficiency, nuclear type 18", "description": "" }, { "id": "MONDO:0032623", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0032623", "name": "MC1DN18", "description": "" }, { "id": "MIM:618240", "resource": "MIM", "url": "https://www.omim.org/entry/618240", "name": "Mitochondrial complex I deficiency, nuclear type 18", "description": "Mitochondrial complex I deficiency, nuclear type 18" } ], "unlinked_id_list": [], "evidence": [ { "id": "0112070", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112070" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W1H9", "url": "https://www.uniprot.org/uniprotkb/Q9W1H9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "NdufAF3", "url": "https://www.uniprot.org/uniprotkb/Q9W1H9", "locus": { "chromosome": "2R", "start_pos": 23866654, "end_pos": 23865414, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0034919", "url": "https://www.ensemblgenomes.org/id/FBgn0034919" } ] } } ], "crossref": [ { "id": "FB:FBgn0034919", "url": "https://alliancegenome.org/gene/FB:FBgn0034919", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "Q9W1H9", "url": "https://alphafold.ebi.ac.uk/entry/Q9W1H9", "database": "AlphaFoldDB", "categories": [] }, { "id": "FBgn0034919", "url": "https://bgee.org/?page=gene&gene_id=FBgn0034919", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05125", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05125", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0034919", "url": "https://flybase.org/reports/FBgn0034919", 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"categories": [ "Enzyme and Pathway" ] }, { "id": "NP_611840", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611840", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W1H9", "url": "https://www.uniprot.org/uniprotkb/Q9W1H9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W1H9-1", "url": "https://www.uniprot.org/uniprotkb/Q9W1H9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIARTLRTVGRQGRNLLLPRITACRPLHAIPANFSKAYDHDGKTKVTIFNTETDLGLMVTGYSQYGFRLNNDMVLIGPISVFPRSVLSWNVNSFEDINEDSLSLFPTLEPKIDVLIIGIGDQAPPPALSKRIIEFMKKYKINVEILRTEQACATFNFLNAENRMVACALIPPLHLSYNENDILQAKLRKKELYETE", "length": 196, "header": "sp|Q9W1H9-1|NDUF3_DROME Isoform 1 of NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 OS=Drosophila melanogaster OX=7227 GN=NdufAF3 PE=1 SV=1 CANONICAL=Q9W1H9-1" }, "isoforms": [ { "isoform_ac": "Q9W1H9-1", "url": "https://www.uniprot.org/uniprotkb/Q9W1H9/entry#Q9W1H9-1", "sequence": { "sequence": "MIARTLRTVGRQGRNLLLPRITACRPLHAIPANFSKAYDHDGKTKVTIFNTETDLGLMVTGYSQYGFRLNNDMVLIGPISVFPRSVLSWNVNSFEDINEDSLSLFPTLEPKIDVLIIGIGDQAPPPALSKRIIEFMKKYKINVEILRTEQACATFNFLNAENRMVACALIPPLHLSYNENDILQAKLRKKELYETE", "length": 196, "header": "sp|Q9W1H9-1|NDUF3_DROME Isoform 1 of NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 OS=Drosophila melanogaster OX=7227 GN=NdufAF3 PE=1 SV=1 CANONICAL=Q9W1H9-1" }, "locus": { "chromosome": "2R", "start_pos": 23865414, "end_pos": 23866654, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0072128", "url": "https://www.ensemblgenomes.org/id/FBtr0072128" }, { "database": "Ensembl Peptide", "id": "FBpp0072037", "url": "https://www.ensemblgenomes.org/id/FBpp0072037" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, 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Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W1H9", "url": "https://www.uniprot.org/uniprotkb/Q9W1H9" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "A Drosophila full-length cDNA resource.", "journal": "Genome Biol.", "date": "2002", "authors": "Stapleton M, Carlson J, Brokstein P, Yu C, Champe M, George R, Guarin H, Kronmiller B, Pacleb J, Park S, Wan K, Rubin GM, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1H9", "url": "https://www.uniprot.org/uniprotkb/Q9W1H9" } ], "reference": [ { "type": "PubMed", "id": "12537569", "url": "https://glygen.org/publication/PubMed/12537569" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1H9", "url": "https://www.uniprot.org/uniprotkb/Q9W1H9" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "Dissecting the concordant and disparate roles of NDUFAF3 and NDUFAF4 in mitochondrial complex I biogenesis.", "journal": "iScience", "date": "2021-08-20", "authors": "Murari Anjaneyulu, Rhooms Shauna-Kay, Garcia Christian, Liu Tong, Li Hong, Mishra Bibhuti, Deshong Cassie, Owusu-Ansah Edward", "evidence": [ { "database": "UniProtKB", "id": "Q9W1H9", "url": "https://www.uniprot.org/uniprotkb/Q9W1H9" } ], "reference": [ { "type": "PubMed", "id": "34386730", "url": "https://glygen.org/publication/PubMed/34386730" } ] } ], "pathway": [ { 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"https://www.uniprot.org/uniprotkb/Q9W1I8" } ] }, { "name": "Snap29", "type": "synonym", "evidence": [ { "id": "NP_523831", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523831" } ] }, { "name": "Ubisnap", "type": "synonym", "evidence": [ { "id": "NP_523831", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523831" }, { "id": "Q9W1I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W1I8" } ] }, { "name": "Usnp", "type": "synonym", "evidence": [ { "id": "NP_523831", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523831" }, { "id": "Q9W1I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W1I8" } ] }, { "name": "dSNAP-29", "type": "synonym", "evidence": [ { "id": "NP_523831", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523831" }, { "id": "Q9W1I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W1I8" } ] }, { "name": "snap29", 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"NP_523831", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523831" } ] }, { "name": "Synaptosomal-associated protein 29kDa", "type": "synonym", "evidence": [ { "id": "NP_523831", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523831" }, { "id": "Q9W1I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W1I8/entry#names_and_taxonomy" } ] }, { "name": "ubisnap", "type": "synonym", "evidence": [ { "id": "NP_523831", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_523831" } ] } ], "function": [], "disease": [ { "disease_id": "DOID:0060337", "recommended_name": { "id": "DOID:0060337", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0060337", "name": "CEDNIK syndrome", "description": "A syndrome that has_material_basis_in homozygous mutation in the SNAP29 gene and characterized by a unique constellation of clinical manifestations including microcephaly, severe neurologic 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"MAHNYLQPVHDHFDDVDRFEDVDDDLFLQNKRTGAAKLPQQRSTNPFEMDDDDEEEITSSPSVAAQRLAYAEKRRAIEQRTLDSTNKSLGLLYETQEVGKATAVELAKQREQLEKTSHQLDEISSTLRFSQRHLTGLKSVFGGLKNYLSGNRDQPPTATGSPTGSQSSQEANSNINQGACGGASPSAPLSPAERYDNHPVSQLRGDPSSTYQPQRQAANPFQAQIDSNLEEMCSNLSVLKMLATDLGGEIESQNELLDNMNYKIEDVDLKIHKQNKDMSKLLKK", "length": 284, "header": "tr|Q9W1I8-1|Q9W1I8_DROME Isoform 1 of Synaptosomal-associated protein 29kDa OS=Drosophila melanogaster OX=7227 GN=Snap29 PE=1 SV=1 CANONICAL=Q9W1I8-1" }, "isoforms": [ { "isoform_ac": "Q9W1I8-1", "url": "https://www.uniprot.org/uniprotkb/Q9W1I8/entry#Q9W1I8-1", "sequence": { "sequence": "MAHNYLQPVHDHFDDVDRFEDVDDDLFLQNKRTGAAKLPQQRSTNPFEMDDDDEEEITSSPSVAAQRLAYAEKRRAIEQRTLDSTNKSLGLLYETQEVGKATAVELAKQREQLEKTSHQLDEISSTLRFSQRHLTGLKSVFGGLKNYLSGNRDQPPTATGSPTGSQSSQEANSNINQGACGGASPSAPLSPAERYDNHPVSQLRGDPSSTYQPQRQAANPFQAQIDSNLEEMCSNLSVLKMLATDLGGEIESQNELLDNMNYKIEDVDLKIHKQNKDMSKLLKK", "length": 284, "header": "tr|Q9W1I8-1|Q9W1I8_DROME Isoform 1 of Synaptosomal-associated protein 29kDa OS=Drosophila melanogaster OX=7227 GN=Snap29 PE=1 SV=1 CANONICAL=Q9W1I8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W1I8", "url": "https://www.uniprot.org/uniprotkb/Q9W1I8" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W1I8", "url": "https://www.uniprot.org/uniprotkb/Q9W1I8" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1I8", "url": "https://www.uniprot.org/uniprotkb/Q9W1I8" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1I8", "url": "https://www.uniprot.org/uniprotkb/Q9W1I8" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W1I8", "url": "https://www.uniprot.org/uniprotkb/Q9W1I8" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W1I8", "url": "https://www.uniprot.org/uniprotkb/Q9W1I8" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W1I8", "url": "https://www.uniprot.org/uniprotkb/Q9W1I8" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1I8", "url": "https://www.uniprot.org/uniprotkb/Q9W1I8" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1I8", "url": "https://www.uniprot.org/uniprotkb/Q9W1I8" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9W1K1-1", "uniprot_ac": "Q9W1K1", "uniprot_id": "Q9W1K1_DROME", "mass": { "chemical_mass": 16054.0, "monoisotopic_mass": 16054.0 }, "refseq": { "ac": "NP_611825", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611825" }, "gene_names": [ { "name": "Dmel\\CG11300", "type": "recommended", "evidence": [ { "id": "Q9W1K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W1K1" } ] }, { "name": "BcDNA:LP08443", "type": "synonym", "evidence": [ { "id": "NP_611825", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611825" }, { "id": "Q9W1K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W1K1" } ] }, { "name": "CG11300", "type": "synonym", "evidence": [ { "id": "NP_611825", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611825" 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systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1K1", "url": "https://www.uniprot.org/uniprotkb/Q9W1K1" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1K1", "url": "https://www.uniprot.org/uniprotkb/Q9W1K1" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W1K1", "url": "https://www.uniprot.org/uniprotkb/Q9W1K1" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W1K1", "url": "https://www.uniprot.org/uniprotkb/Q9W1K1" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W1K1", "url": "https://www.uniprot.org/uniprotkb/Q9W1K1" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1K1", "url": "https://www.uniprot.org/uniprotkb/Q9W1K1" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1K1", "url": "https://www.uniprot.org/uniprotkb/Q9W1K1" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"37757", "url": "https://www.ncbi.nlm.nih.gov/gene/37757", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002562", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002562", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056589", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG4051", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG4051", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GNPNKDQ", "url": "https://omabrowser.org/oma/group/GNPNKDQ/", "database": "OMA", "categories": [ "Protein 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"https://www.uniprot.org/uniprotkb/Q9W1K4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W1K4-1", "url": "https://www.uniprot.org/uniprotkb/Q9W1K4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"length": 1004, "header": "tr|Q9W1K4-1|Q9W1K4_DROME Isoform 1 of Egalitarian, isoform C OS=Drosophila melanogaster OX=7227 GN=egl PE=1 SV=4 CANONICAL=Q9W1K4-1" }, "isoforms": [ { "isoform_ac": "Q9W1K4-1", "url": "https://www.uniprot.org/uniprotkb/Q9W1K4/entry#Q9W1K4-1", "sequence": { "sequence": "MESMEYEMARNMTLLFFLERLLDKGEPRTVHDLSCQFGNKEFTKEMRQIAGGSQSGLKKFLAQYPAIFLVDGDYVQVNAYQHHNADDGGCGGKRDYIQEAKDYFKNKMLQYGAAAEVPVRSLLGHRSQASPQVRHISGQHIKEFTDFLMKHTDTFKVTDDYVMLVGCENMTDLPARDRLHLPQSNIDTRGTQQMLDFFAQCIEVKGPLLVDQLFHLLTTNFPQDQWLRMFKTPGDLSSFLKLFADCFHIQANLVTLLQKPKLSDTHIQQAQAQTREQFNALNNNNSASIRKQEPTPGGGGVGGVSSVQQRLQSPALRTNGHTNNNNGSNGSNNNNNNNNSIACPNFKLNAPVSNVMGGQSQGFGQPKSEPSSGFDSYVPMSELKLENLCENNYPSANTCYGPINNSSQQTQQVQTQQQQQPQHATQNPAEQRLNSVNQTLKQRINTLVIRTLAENLEKDKQSLANQQGGPISPHASPVHSIANSSSNQNAGSAANNANSNSNANPNNANHSPSHSYFVGDTWKIKVLQNTTVIANVKQSVFVTDIILKYAAKNESIVVSLDCEGINLGLKGEITLIEIGTTRGEAFLFDVQSCPAMVTDGGLKTVLEHDQVIKVIHDCRNDAANLYLQFGILLRNVFDTQAAHAILQYQESGKQVYKAKYISLNSLCEQYNAPCNPIKDQLKQIYRRDQKFWAKRPLTREMMLYAAGDVLVLIHDQLFGNLARQIKPENRALFSELCTEQILMQIKPNEVKIRKKQRKVSTEVSDLKQKLAQTSKSIVLSNREIRLLRYMDLTEDEKERLKGYYKVAKKLEKMESAGNPSKDQSDSEDEQEPNENDAFPSLDSVPSDNSLSGTFSPRFSSEPPSLTESMQMLEEILQNKSMDRIARIDKLEAILTTATSLPCEQIIASNSMQEQLGSSIATTENLQIIREKSKNIKNCNCQGERSVTPIMRTTDKRVVKLVDAESQTLSTGDVVITKIFFQDEHERAKEAALLSNSPAKRVSPT", "length": 1004, "header": "tr|Q9W1K4-1|Q9W1K4_DROME Isoform 1 of Egalitarian, isoform C OS=Drosophila melanogaster OX=7227 GN=egl PE=1 SV=4 CANONICAL=Q9W1K4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 295, "start_aa": "Thr", "end_pos": 295, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr295", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W1K4", "url": "https://www.uniprot.org/uniprotkb/Q9W1K4" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W1K4", "url": "https://www.uniprot.org/uniprotkb/Q9W1K4" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1K4", "url": "https://www.uniprot.org/uniprotkb/Q9W1K4" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1K4", "url": "https://www.uniprot.org/uniprotkb/Q9W1K4" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W1K4", "url": "https://www.uniprot.org/uniprotkb/Q9W1K4" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W1K4", "url": "https://www.uniprot.org/uniprotkb/Q9W1K4" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W1K4", "url": "https://www.uniprot.org/uniprotkb/Q9W1K4" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1K4", "url": "https://www.uniprot.org/uniprotkb/Q9W1K4" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1K4", "url": "https://www.uniprot.org/uniprotkb/Q9W1K4" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W1K4", "url": "https://www.uniprot.org/uniprotkb/Q9W1K4" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W1K4", "url": "https://www.uniprot.org/uniprotkb/Q9W1K4" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG4051", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG4051", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "Q9W1K4", "url": "https://www.uniprot.org/uniprotkb/Q9W1K4" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9W1K4", "url": "https://www.uniprot.org/uniprotkb/Q9W1K4" } ], "pmid": "" }, { "name": "3'-5' exonuclease activity", "id": "GO:0008408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008408", "evidence": [ { "database": "UniProtKB", "id": "Q9W1K4", "url": "https://www.uniprot.org/uniprotkb/Q9W1K4" } ], "pmid": "" } ] }, { "name": "Biological Process", 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"resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, type 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "HPC9", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "prostate cancer, hereditary, 10", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "HPC10", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "prostate cancer, hereditary, 10", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, 12", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the EHBP1 gene." }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "EHBP1 familial prostate cancer", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "familial prostate cancer caused by mutation in EHBP1", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, 12", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, type 12", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "HPC12", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, 13", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the MSMB gene." }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "MSMB familial prostate cancer", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "familial prostate cancer caused by mutation in MSMB", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, 13", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, type 13", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "HPC13", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "HPC11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "HPC14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "prostate cancer, hereditary, 15", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "HPC15", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "prostate cancer, hereditary, 15", "description": "" }, { "id": "MONDO:0700275", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0700275", "name": "prostate cancer, hereditary", "description": "An instance of prostate cancer that is caused by an inherited genomic modification in an individual. Familial prostate cancer (FPC) is a malignant tumor of the prostate with an early onset. FPC is either asymptomatic or causes mictionary symptoms, erectile dysfunction, bone pain, venous compression and infectious or inflammatory syndrome (for the metastatic forms). It is also characterized by familial antecedents." }, { "id": "MIM:601518", "resource": "MIM", "url": "https://www.omim.org/entry/601518", "name": "Prostate cancer, hereditary, 1", "description": "Prostate cancer, hereditary, 1" }, { "id": "MIM:610997", "resource": "MIM", "url": "https://www.omim.org/entry/610997", "name": "Prostate cancer, hereditary, 9", "description": "Prostate cancer, hereditary, 9" }, { "id": "MIM:611868", "resource": "MIM", "url": "https://www.omim.org/entry/611868", "name": "Prostate cancer, hereditary, 12", "description": "Prostate cancer, hereditary, 12" }, { "id": "MIM:611928", "resource": "MIM", "url": "https://www.omim.org/entry/611928", "name": "Prostate cancer, hereditary, 13", "description": "Prostate cancer, hereditary, 13" }, { "id": "MIM:611955", "resource": "MIM", "url": "https://www.omim.org/entry/611955", "name": "Prostate cancer, hereditary, 11", "description": "Prostate cancer, hereditary, 11" }, { "id": "MIM:176807", "resource": "MIM", "url": "https://www.omim.org/entry/176807", "name": "Prostate cancer", "description": "Prostate cancer" } ], "unlinked_id_list": [], "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ] }, { "disease_id": "DOID:10534", "recommended_name": { "id": "DOID:10534", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach." }, "synonyms": [ { "id": "DOID:10534", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10534", "name": "gastric cancer", "description": "" }, { "id": "DOID:10534", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10534", "name": "gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer", "description": "A primary or metastatic malignant neoplasm involving the stomach." }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "Ca lesser curvature - stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "GC", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "cancer of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer risk after h. pylori infection", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer, somatic", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric tumor", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric tumour", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant stomach neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of body of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of greater curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of body of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of greater curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "stomach cancer", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "Ca body - stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "ca greater curvature of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of body of stomach", "description": "" }, { "id": "MIM:613659", "resource": "MIM", "url": "https://www.omim.org/entry/613659", "name": "Gastric cancer", "description": "Gastric cancer" } ], "unlinked_id_list": [], "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ] }, { "disease_id": "DOID:11054", "recommended_name": { "id": "DOID:11054", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder." }, "synonyms": [ { "id": "DOID:11054", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11054", "name": "bladder cancer", "description": "" }, { "id": "DOID:11054", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11054", "name": "tumor of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder cancer", "description": "A primary or metastatic malignant neoplasm involving the bladder." }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "tumor of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "tumour of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "bladder cancer, somatic", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "cancer of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant bladder neoplasm", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant bladder tumor", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant bladder tumour", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of the urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm, bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm, urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of the urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor, urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumour of bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumour of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumour of the urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumour of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant urinary bladder neoplasm", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant urinary bladder tumor", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant urinary bladder tumour", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder cancer", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder malignant neoplasm", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder malignant tumor", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder malignant tumour", "description": "" }, { "id": "MIM:109800", "resource": "MIM", "url": "https://www.omim.org/entry/109800", "name": "Bladder cancer", "description": "Bladder cancer" } ], "unlinked_id_list": [], "evidence": [ { "id": "11054", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11054" } ] }, { "disease_id": "DOID:1324", "recommended_name": { "id": "DOID:1324", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung." }, "synonyms": [ { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer", "description": "A malignant neoplasm involving the lung." }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "adenocarcinoma of lung, response to tyrosine kinase inhibitor in, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "adenocarcinoma of lung, somatic", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "cancer of lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer, protection against, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer, resistance to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer, 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"https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant neoplasm of the lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant tumor of lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant tumor of the lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant tumour of lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant tumour of the lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "nonsmall cell lung cancer, response to tyrosine kinase inhibitor in, autosomal dominant, somatic 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"https://disease-ontology.org/term/DOID:3907", "name": "Epidermoid cell carcinoma of the lung", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "3907", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3907" } ] }, { "disease_id": "DOID:3910", "recommended_name": { "id": "DOID:3910", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3910", "name": "lung adenocarcinoma", "description": "A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin." }, "synonyms": [ { "id": "DOID:3910", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3910", "name": "bronchogenic lung adenocarcinoma", "description": "" }, { "id": "DOID:3910", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3910", "name": "nonsmall cell adenocarcinoma", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "3910", "database": "AGR", "url": 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"categories": [ "Gene Expression" ] }, { "id": "FBgn0034887", "url": "https://flybase.org/reports/FBgn0034887", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "37742", "url": "https://www.ncbi.nlm.nih.gov/gene/37742", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000863", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000863", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG5428", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG5428", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RDFKLNM", "url": "https://omabrowser.org/oma/group/RDFKLNM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W1L8", "url": "https://www.orthodb.org/?gene=Q9W1L8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11783", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11783", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00685", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00685", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_611815", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611815", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W1L8", "url": "https://www.uniprot.org/uniprotkb/Q9W1L8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W1L8-1", "url": "https://www.uniprot.org/uniprotkb/Q9W1L8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPQSSFFAKSVPFEQIDKLAISGGYSSIFASSKPSVPVVGNWEQRFCRLADTFQPVLDRVYDFEVRDDDVWIVTLPKCGTTWMQELAWLVINECDFETAKSVDLTHRSPFLEFNGVVPNVPHDTIAAANALPSPRLIKSHLPAWMLPRQIWSKRPKIIYVYRNPKDAAISYFHHWRGMVGYQGTKSDFMHSFIDGYVNFTPCWPHILDFWQLRHEPNIFFTSYERMKGQLGQVISEVAQFLERSVSQEQMQQMQRHLSFESMRDNPACNHVKEFESMKAAAGREVEEFRFVRRGVVGSHKDELTADIIREFDLWSDSNLRDFKLNMDDFANYSKFAST", "length": 338, "header": "tr|Q9W1L8-1|Q9W1L8_DROME Isoform 1 of Sulfotransferase 1 OS=Drosophila melanogaster OX=7227 GN=St1 PE=3 SV=3 CANONICAL=Q9W1L8-1" }, "isoforms": [ { "isoform_ac": "Q9W1L8-1", "url": "https://www.uniprot.org/uniprotkb/Q9W1L8/entry#Q9W1L8-1", "sequence": { "sequence": "MPQSSFFAKSVPFEQIDKLAISGGYSSIFASSKPSVPVVGNWEQRFCRLADTFQPVLDRVYDFEVRDDDVWIVTLPKCGTTWMQELAWLVINECDFETAKSVDLTHRSPFLEFNGVVPNVPHDTIAAANALPSPRLIKSHLPAWMLPRQIWSKRPKIIYVYRNPKDAAISYFHHWRGMVGYQGTKSDFMHSFIDGYVNFTPCWPHILDFWQLRHEPNIFFTSYERMKGQLGQVISEVAQFLERSVSQEQMQQMQRHLSFESMRDNPACNHVKEFESMKAAAGREVEEFRFVRRGVVGSHKDELTADIIREFDLWSDSNLRDFKLNMDDFANYSKFAST", "length": 338, "header": "tr|Q9W1L8-1|Q9W1L8_DROME Isoform 1 of Sulfotransferase 1 OS=Drosophila melanogaster OX=7227 GN=St1 PE=3 SV=3 CANONICAL=Q9W1L8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W1L8", "url": "https://www.uniprot.org/uniprotkb/Q9W1L8" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W1L8", "url": "https://www.uniprot.org/uniprotkb/Q9W1L8" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1L8", "url": "https://www.uniprot.org/uniprotkb/Q9W1L8" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1L8", "url": "https://www.uniprot.org/uniprotkb/Q9W1L8" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W1L8", "url": "https://www.uniprot.org/uniprotkb/Q9W1L8" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W1L8", "url": "https://www.uniprot.org/uniprotkb/Q9W1L8" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W1L8", "url": "https://www.uniprot.org/uniprotkb/Q9W1L8" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1L8", "url": "https://www.uniprot.org/uniprotkb/Q9W1L8" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1L8", "url": "https://www.uniprot.org/uniprotkb/Q9W1L8" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W1L8", "url": "https://www.uniprot.org/uniprotkb/Q9W1L8" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W1L8", "url": "https://www.uniprot.org/uniprotkb/Q9W1L8" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG5428", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG5428", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0B4KF40-1", "protein_name": "2.8.2.-", "gene_name": "St3", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNRVQVTPRSYPTNLIDKDWGNRKLFYTKDSENFLRLVHDMKLRDDDVWIVTLPKCGTTWMQELLWLLLNNCDFEGALAKDQELRTPFLEFGYSVFHDPNRSFGPIEDLKSPRLIKSHLSLALLPSKLWEGKNKVIYVSRNPLDSYVSRYYHGVSFGFNYGKSLHQYFDEVLASDDFPTEFIEHAHEFYQLRNEPWVFYTSFEMMKKDLRGVINDVSRFLNKPINDQQMEKLLKHLSFAEMKKNPTTNHLWELAQVQHENAGKEMHPFVRRGDVNGYKDELKPEQIEKANVRIQEVLAKNGVTLDELLLLKDQDWPCSGLCTQHSQTNSEAITLRNGPKAHQHQCSSACTRWLCVRVKVVKAESRGRTGPILMLMQGSRDAEMPTPPPQREAKNGKQATFIAGREVFTVLWERRISQDVNRGSCTMFAPHSLPVTSRLLLLVVTLLFCPVQAHLSKRSYSDQSVHGYMTERTCWWNEVCKEEFQSLFRCKCPQFSYCRSPGRYYNAYCSMTDTGYIWTQPNWDWGA", "length": 526 }, "evidence": [ { "id": "RGD:3727", "url": "https://alliancegenome.org/gene/RGD:3727#orthology", "database": "AGR" }, { 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"https://alliancegenome.org/gene/RGD:621064#orthology", "database": "AGR" }, { "id": "RGD:620491", "url": "https://alliancegenome.org/gene/RGD:620491#orthology", "database": "AGR" }, { "id": "RGD:1306542", "url": "https://alliancegenome.org/gene/RGD:1306542#orthology", "database": "AGR" }, { "id": "RGD:1305885", "url": "https://alliancegenome.org/gene/RGD:1305885#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A0A1B0GRF0-1", "protein_name": "Sulfotransferase", "gene_name": "Sult2a7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSDYVWFEGMPFPCMGFNKEIIGKIRHSFVMREDTVVLSYPKSGMTWLVEIVCLIQKKGDTKWIQSVPIWDRSPWLENESGYFELVNKEGPRLMTSHLPIHLFHKSLFSSKTKIIYIFRNPRDILVSGYFFWSKTNLMKNPGSLETYFEWFLKGNVPYGSWFEHIRGWLSMREEKNFLLLCYDDFKKLLPIHPLFVVHVYHDDGDDDGGGGGDHDDDTRGTIEKICEFLGKKLEPDEMNLILKYSSFQAMKENKMSNFSIVRKDIATNDLQLLREGATGDWKNHFTVALAEAFDKVYQEKMAGFPIGLFPWE", "length": 313 }, "evidence": [ { "id": 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"MGI:3645972", "url": "https://alliancegenome.org/gene/MGI:3645972#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PQS2-1", "protein_name": "Sulfotransferase", "gene_name": "sult1st4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTDHEFPDVASMKPCIRPDMFDFEGVFLTRFFTDNWENVKNFQARPDDILIATYPKAGYSAIKNPRTTWVSYILDLLYFGNDENQTSQPIVQRVPFLESCFQEFSTISGTEMADNLPTSPRLIKTHLPVQLVPKSFWEQNSRVVYVARNAKDNAVSYFHFDRMNMVQPEPGDWDSYLDKFMQGQNVFGSWFDHVSGWWQKKRSYPNMLYMFFEDLSEDTGREVNRLCSFLGLSTSVQEKEKITKGVQFDAMKQNTLINHVTIPFLDCKISPFMRKGKVGDWKSHFTVAQNERFDEVYKQKMKNSGVTFRTEI", "length": 312 }, "evidence": [ { "id": "HGNC:17845", "url": "https://alliancegenome.org/gene/HGNC:17845#orthology", "database": "AGR" }, { "id": "HGNC:11453", "url": "https://alliancegenome.org/gene/HGNC:11453#orthology", "database": "AGR" }, { "id": "HGNC:11454", "url": "https://alliancegenome.org/gene/HGNC:11454#orthology", "database": "AGR" }, { 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"Zebrafish" }, { "uniprot_canonical_ac": "A0AB13A8R3-1", "protein_name": "Sulfotransferase", "gene_name": "sult1st9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEIQGKSSTDLPDRPEIFEFEGISMVEHFTKNWENVKNFQARPDDILIATYPKAGTTWVSNILDLLYFGKEDPKRQTTKPIYKRVPFLESCFPEMQSGTELANNLPTSPRLIKTHLPVQLVPQSFWEKNSRVAYVARNAKDNAVSYFHFNRMNKAQPEPGDWNTFLEEFMKGKMVFGSWFDHVCGWWEKKKTYPNLHYMLYEDMAKDIKGEVESLCTFLKLSRSDEEKEKIINGIQFDAMKQNKMTNYSTVLVMDFTISPFMRKGKVGDWKNHFTVAQNEQFNEDYKQKMKNSTLKFPTEHGRKTRGGRGRHVPSHPRLVPPPQKRKNLNYKKKNLNCEKYTYIYLK", "length": 347 }, "evidence": [ { "id": "HGNC:11377", "url": "https://alliancegenome.org/gene/HGNC:11377#orthology", "database": "AGR" }, { "id": "HGNC:30004", "url": "https://alliancegenome.org/gene/HGNC:30004#orthology", "database": "AGR" }, { "id": "HGNC:11455", "url": "https://alliancegenome.org/gene/HGNC:11455#orthology", "database": "AGR" }, { "id": "MGI:98431", "url": "https://alliancegenome.org/gene/MGI:98431#orthology", "database": "AGR" }, { "id": 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"MENTPLKFPHEIRDVEESTNAELLDHFHGERTGFVQVGSEGYFFPHKYKDEAERYYNFEARPDDVWIATVPRSGTTWTQELIWLVANGLDFEHAQERPLTERFPFFEFPLFVHPKIKEELQEENRDSAEALEFIEKIARPGYEALSEIPRSQRRFIKTHFPFSLMPPSVLEKKCKVIYVVRDPKDVAVSYYHLNRLFRTQGYVGDFERYWHYFQNGLNPWLPYYSHVKEAREHAHLSNVLFLRYEDMLADLPGAINSIASFLECPPKPEDMDRLLDHLSIRSFRENKSVNMHEMASVGVLNKGEAGFVRSGAKTAYQPQQEFVENPKLLKSANEWVEQNIKSFKTI", "length": 346 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-030131-1135", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1135#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-722", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-722#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "B2RVI8-1", "protein_name": "Sulfotransferase 2A6", "gene_name": "Sult2a6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMSDYSWFEGIPLPDMWVQKEIVEDVHNKFVVKDEDLIILTYPKSGTNWLIEIVCLIQTKGDPKWIQSVPNWERSPWLESKSGYSVLTSKEGPRLMTSHLPIHLFSKSFFSSKAKVIYLIRNPRDVLVSGYFFWANTNLVKNLESLGIYFEQFLKGNVRYGSWFEHIHGWLSMRERNNFLVLYYEDMKKDAKGTIKKICDFLGKNLGPDELDLVLKYSSFQAMKENNMSNYSLIKEDQITNGLKLMRKGTTGDWKNHFTVAQTEAFDKVFQDKMVGFPPGMFPWE", "length": 285 }, "evidence": [ { "id": "RGD:3727", "url": "https://alliancegenome.org/gene/RGD:3727#orthology", "database": "AGR" }, { "id": "HGNC:11458", "url": "https://alliancegenome.org/gene/HGNC:11458#orthology", "database": "AGR" }, { "id": "MGI:3648915", "url": "https://alliancegenome.org/gene/MGI:3648915#orthology", "database": "AGR" }, { "id": "RGD:621337", "url": "https://alliancegenome.org/gene/RGD:621337#orthology", "database": "AGR" }, { "id": "RGD:1306542", "url": "https://alliancegenome.org/gene/RGD:1306542#orthology", "database": "AGR" }, { "id": "FB:FBgn0034887", "url": "https://alliancegenome.org/gene/FB:FBgn0034887#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z1W5-1", "protein_name": "Sulfotransferase", "gene_name": "Sult2a3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMSDYYWFEGIPFPAIAYQKEILEDIRNKFVVKEEDLLILTYPKSGTHWLIEIVCLIQTRGDPKWIQTVPIWDRSPWLETDIGYLALINKEGPRLISSHLPVHLFFKSFFSSKAKAIYLIRNPRDILVSGYFFYGNTNLVKNPGSLRTYFEWFLKGNVIYGSWFEHVRGWLSMREWDNFLVLYYEDMKKDTKGTIKKICDFLGKKLEPDELDLVLKYSSFQAMKENNMSNYSLVSEDMITNGLKLMRKGTTGDWKNHFTVAQAEAFNKVFQEKMAGFPQGMFPWE", "length": 285 }, "evidence": [ { "id": "HGNC:11458", "url": "https://alliancegenome.org/gene/HGNC:11458#orthology", "database": "AGR" }, { "id": "MGI:3645873", "url": "https://alliancegenome.org/gene/MGI:3645873#orthology", "database": "AGR" }, { "id": "FB:FBgn0034887", "url": "https://alliancegenome.org/gene/FB:FBgn0034887#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D4ADX9-1", "protein_name": "Sulfotransferase", "gene_name": "Sult5a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQRETLCLAPDSTSMNERMNTTEIFDGIRFPGFLHTLESLKAACSFQFQDTDVLLVTFPKSGTTWMQQVLSLIFCEGHLWPIHHLPNWARMPWMEQASFSSLLSKLNTSWPRLLTSHLNAKGLSPALMKSKAKVVYMGRNPKDVLVSYYHFHQIAGFLPNPSSFEDFADEFLEGTGFFGSWFDHVKGWLGLQKDLTLLFVTYEELHQEPRSTIRKLSEFLGRTLGPKEEEIILEHSSFSFMSQSNMVNYSLLSKEIIDQSQGKFLRKGVVGNWREYFTPELNEKFNAVYQSKMGDSGLSLPWTMD", "length": 305 }, "evidence": [ { "id": "RGD:1310002", "url": "https://alliancegenome.org/gene/RGD:1310002#orthology", "database": "AGR" }, { "id": "FB:FBgn0034887", "url": "https://alliancegenome.org/gene/FB:FBgn0034887#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7F734-1", "protein_name": "Sulfotransferase", "gene_name": "sult2st1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSESELFMVHKGVFLTTLVHPAESLKYYEDFTFRPDDILIVTYPKSGTTWMQEIVPLVVSEGDLTPVLTVPNWDRVPWLEEHRAILLSLEQRASPRIFATHFHHQMMNPSYFKIKPRVLYVMRNPKDVFISSYHFHEMASFLVSPGTQDEFMEKFLDGTIMFGSWFDHVKSWLNAGEQEHILYLCYEDMISDLKASVEKIATFLGKSLSSEVVEKIADHCVFKNMKQNKMSNYSLVPEEFMDQKKSEFLRKGIVGDWKNHFSTAQEQKFNAVYQEKMKDVKFSFPWD", "length": 287 }, "evidence": [ { "id": "RGD:3727", "url": "https://alliancegenome.org/gene/RGD:3727#orthology", "database": "AGR" }, { "id": "HGNC:11458", "url": "https://alliancegenome.org/gene/HGNC:11458#orthology", "database": "AGR" }, { "id": "HGNC:11459", "url": "https://alliancegenome.org/gene/HGNC:11459#orthology", "database": "AGR" }, { "id": "MGI:3645854", "url": "https://alliancegenome.org/gene/MGI:3645854#orthology", "database": "AGR" }, { "id": "MGI:3645873", "url": "https://alliancegenome.org/gene/MGI:3645873#orthology", "database": "AGR" }, { "id": "MGI:3648915", "url": "https://alliancegenome.org/gene/MGI:3648915#orthology", "database": "AGR" }, { "id": "MGI:1926342", "url": "https://alliancegenome.org/gene/MGI:1926342#orthology", "database": "AGR" }, { "id": "MGI:107550", "url": "https://alliancegenome.org/gene/MGI:107550#orthology", "database": "AGR" }, { "id": "MGI:3645246", "url": "https://alliancegenome.org/gene/MGI:3645246#orthology", "database": "AGR" }, { "id": "MGI:98430", "url": "https://alliancegenome.org/gene/MGI:98430#orthology", "database": "AGR" }, { "id": "MGI:3648378", "url": "https://alliancegenome.org/gene/MGI:3648378#orthology", "database": "AGR" }, { "id": "MGI:1924221", "url": "https://alliancegenome.org/gene/MGI:1924221#orthology", "database": "AGR" }, { "id": "RGD:621337", "url": "https://alliancegenome.org/gene/RGD:621337#orthology", "database": "AGR" }, { "id": "RGD:1306542", "url": "https://alliancegenome.org/gene/RGD:1306542#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QYJ6-1", "protein_name": "Sulfotransferase 6B1", "gene_name": "sult6b1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSQMKSRMETAAKMKDEDKLYRRDGILYSTVLSPPETLDKLKDLQAREDDLILVAYPKCGFNWMVAVLRKIINASTGKDEKPPERPPLVEFLPPTVQEEMAQMPPPRLLGTHLHPDNMPATFFTKKPKILVVFRNPKDTVVSYYHFMNKNPVLPNAESWDKFFSDFMTGDVSWGSYFDHALAWEKRIDDPNVMIVMYEDLKQNLPEGVKKISEFFSLPLTDEQVSSIAGQSTFSAMVENSQKSHGNFGSIFFRKGEVGDWKNHFSEAQSKQMDELYHSKLAGTKLAARMNYDLYCQ", "length": 296 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050417-228", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-228#orthology", "database": "AGR" }, { "id": "FB:FBgn0034887", "url": "https://alliancegenome.org/gene/FB:FBgn0034887#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3V9R3-1", "protein_name": "Sulfotransferase 1 family member D1", "gene_name": "Sult1d1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDNKLDVFRRELVDVQGIPLFWSIAEQWSQVESFEARPDDILISTYPKSGTTWISEILDLIYNNGDAEKCKRDAIYRRVPFMELIIPGITNGVEMLNNMQSPRLVKTHLPVQLLPSSFWKNDCKMIYVARNAKDVAVSYYYFHQMAKMHPEPGTWEEFLEKFMAGQVSFGPWYDHVKGWWEKRKEYRILYLFYEDMKEDPKCEIQKVLKFLEKDIPEEVVNKILYHSSFSVMKANPSANYTTMMKEEMDQSVSPFMRKGISGDWKNQFTVAQYEKFEEDYVKKMEESTLKFRSEI", "length": 295 }, "evidence": [ { "id": "MGI:1926341", "url": "https://alliancegenome.org/gene/MGI:1926341#orthology", "database": "AGR" }, { "id": "RGD:620491", "url": "https://alliancegenome.org/gene/RGD:620491#orthology", "database": "AGR" }, { "id": "FB:FBgn0034887", "url": "https://alliancegenome.org/gene/FB:FBgn0034887#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G5E904-1", "protein_name": "Sulfotransferase", "gene_name": "Sult3a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDNKDEDIFKFKGYNFLRALVSMDIVKNMEDYEIRDDDIFIVTYPKSGTTWTQQILCLICFESHRNGTENIATIDRIPSFEYNIHKLDYAKMPSPRIFTSHIPYYLVPKGLKDKKAKIIYVYRNPKDVLISFFHFSNLMVVLKASDTLENFMQRFLNGNLVGSLWFDHIRGWYEHRHDFNIMFMSFEDMKKDLRSSVLKICSFLEKELSEEDMDAVVRQATFEKMKADPRANNEHIIKDELGTRNNTGAFLRKGIVGDWKHYLTVDQSERFDKIFHMNMKNIPLKFIWNINEK", "length": 293 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-030131-1135", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1135#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-722", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-722#orthology", "database": "AGR" }, { "id": "MGI:3645972", "url": "https://alliancegenome.org/gene/MGI:3645972#orthology", "database": "AGR" }, { "id": "FB:FBgn0034887", "url": "https://alliancegenome.org/gene/FB:FBgn0034887#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6K9-1", "protein_name": "Sulfotransferase", "gene_name": "Sult2a5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMSDYNWFEGIPFPAISYQREILEDIRNRFVVKEEDLLILTYPKSGTNWLVEIVCLIQTKGDPKWIQTVPNWDRSPWIETDIGYPALINKEGPRLISSHLPIHLFSKSFFSSKAKAIYLIRNPRDILVSGYFFYGNTNIVKNPGSFGTYFEWFLKGNVIYGSWFEHVRGWLSMREWDNFLVLYYEDLKKDPKGTIKKICDFLGKNLGPDELDLVFKYSSFQAMKENNMSNFSLITEDRVTNGLKLMRKGTTGDWKNHFTVAQAEAFDKVFQEKMAGFPPGMFPWE", "length": 285 }, "evidence": [ { "id": "HGNC:11458", "url": "https://alliancegenome.org/gene/HGNC:11458#orthology", "database": "AGR" }, { "id": "MGI:3648378", "url": "https://alliancegenome.org/gene/MGI:3648378#orthology", "database": "AGR" }, { "id": "FB:FBgn0034887", "url": "https://alliancegenome.org/gene/FB:FBgn0034887#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N245-1", "protein_name": "Sulfotransferase", "gene_name": "Sult2a4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMSDYTWFEGIPFPAISYQREILEDIRNRFVVKEEDLLILTYPKSGTNWLIEIVCLIQTKGDSKWIQTVSIQDRSPWLETNRGYPALINKQGPRLITSHLPIHLFSKSFFSSKAKAIYLIRNPRDILLSGYFFWGNTNLVKNPGSLRTYFEWFLKGNVIYGSWFEHVCGWLSMREWDNFLVLYYEDMKKDTKGTIKKICDFLGKKLEPDELDLVLKYSSFQAMKENNMSNYSLVSEDIITNGFKLMRKGTTGDWKNHFTVAQAEAFDKVFQEKMAGFPPGMFPWE", "length": 285 }, "evidence": [ { "id": "HGNC:11458", "url": "https://alliancegenome.org/gene/HGNC:11458#orthology", "database": "AGR" }, { "id": "MGI:3645854", "url": "https://alliancegenome.org/gene/MGI:3645854#orthology", "database": "AGR" }, { "id": "FB:FBgn0034887", "url": "https://alliancegenome.org/gene/FB:FBgn0034887#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0R952-1", "protein_name": "Sulfotransferase", "gene_name": "Sult6b1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEKSKFIEYIDDALEKSKETALSQLFLTHQGIPYPVTMCTLETFRALDAFEARSDDILLASYPKCGSNWILHIVSELIFAVSKKKYACPEFPVLECGDAEKYQRMKRLPSPRILTTHLHCDKLPQSVFKSKAKILVMFRNPKDTAVSFFHFHNDVPDIPSYASWDEFFRQFIKGQVSWGSYFDFAINWNKHIDEENVKFILYEDLKENLVVGIKQISEFLGFSLTDAQIKTISAQSTFQAMRAKSQETHGAIGPFLFRKGEVGDWKSLFNETQNQEMDERFKESLAGISLGDKLKYDSYCLA", "length": 303 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050417-228", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-228#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O00204-1", "protein_name": "Sulfotransferase 2B1", "gene_name": "SULT2B1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDGPAEPQIPGLWDTYEDDISEISQKLPGEYFRYKGVPFPVGLYSLESISLAENTQDVRDDDIFIITYPKSGTTWMIEIICLILKEGDPSWIRSVPIWERAPWCETIVGAFSLPDQYSPRLMSSHLPIQIFTKAFFSSKAKVIYMGRNPRDVVVSLYHYSKIAGQLKDPGTPDQFLRDFLKGEVQFGSWFDHIKGWLRMKGKDNFLFITYEELQQDLQGSVERICGFLGRPLGKEALGSVVAHSTFSAMKANTMSNYTLLPPSLLDHRRGAFLRKGVCGDWKNHFTVAQSEAFDRAYRKQMRGMPTFPWDEDPEEDGSPDPEPSPEPEPKPSLEPNTSLEREPRPNSSPSPSPGQASETPHPRPS", "length": 365 }, "evidence": [ { "id": "HGNC:11459", "url": "https://alliancegenome.org/gene/HGNC:11459#orthology", "database": "AGR" }, { "id": "MGI:1926342", "url": "https://alliancegenome.org/gene/MGI:1926342#orthology", "database": "AGR" }, { "id": "RGD:1308882", "url": "https://alliancegenome.org/gene/RGD:1308882#orthology", "database": "AGR" }, { "id": "FB:FBgn0034887", "url": "https://alliancegenome.org/gene/FB:FBgn0034887#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O00338-1", "protein_name": "Sulfotransferase 1C2", "gene_name": "SULT1C2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALTSDLGKQIKLKEVEGTLLQPATVDNWSQIQSFEAKPDDLLICTYPKAGTTWIQEIVDMIEQNGDVEKCQRAIIQHRHPFIEWARPPQPSGVEKAKAMPSPRILKTHLSTQLLPPSFWENNCKFLYVARNAKDCMVSYYHFQRMNHMLPDPGTWEEYFETFINGKVVWGSWFDHVKGWWEMKDRHQILFLFYEDIKRDPKHEIRKVMQFMGKKVDETVLDKIVQETSFEKMKENPMTNRSTVSKSILDQSISSFMRKGTVGDWKNHFTVAQNERFDEIYRRKMEGTSINFCMEL", "length": 296 }, "evidence": [ { "id": "MGI:1916333", "url": "https://alliancegenome.org/gene/MGI:1916333#orthology", "database": "AGR" }, { "id": "RGD:621064", "url": "https://alliancegenome.org/gene/RGD:621064#orthology", "database": "AGR" }, { "id": "RGD:1305885", "url": "https://alliancegenome.org/gene/RGD:1305885#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O35400-1", "protein_name": "Sulfotransferase 2B1", "gene_name": "Sult2b1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDGPQPRALWSSSEKNVSEMSWNFGGEYFRYKGIPFPVGMYSPESLSLAENTSNVRDDDIFIVTYPKSGTNWMIEIVCLILKDGDPSWIRSEPIWQRAPWCETIISAFNVLDRPSPRIMSSHLPIELFTKAFFSSKAKVIYVGRNPRDVVVSLYYYSKIAGQLKDPGTPDQFLQNFLKGEVQFGSWFDHIKGWIRMQNQENFLFITYEELQQDLRGSVQRICEFLGRPLGEEALSSVVAHSAFAAMKANTMSNYSLLPASLLDHRQGEFLRKGISGDWKNHFTVAQSEAFDSVYREQMHGVQRFPWDTSEEDSSPDGQPDPEPSPSPASDDPNPGSSQ", "length": 338 }, "evidence": [ { "id": "HGNC:11459", "url": "https://alliancegenome.org/gene/HGNC:11459#orthology", "database": "AGR" }, { "id": "MGI:1926342", "url": "https://alliancegenome.org/gene/MGI:1926342#orthology", "database": "AGR" }, { "id": "RGD:1308882", "url": "https://alliancegenome.org/gene/RGD:1308882#orthology", "database": "AGR" }, { "id": "FB:FBgn0034887", "url": "https://alliancegenome.org/gene/FB:FBgn0034887#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O35403-1", "protein_name": "Amine sulfotransferase", "gene_name": "Sult3a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDNKDEYLLNFKGYNFQKTLVKMEVVENIENYEIRDDDIFIVTYPKSGTIWTQQILSLIYFEGHRNRTENIETIDRAPFFEYNIHKLDYAKMPSPRIFSSHIPYYLVPKGLKDKKAKILYMYRNPKDVLISYFHFSNLMLIFQNPDTVESFMQTFLDGDVVGSLWFDHIRGWYEHRHDFNIMFMSFEDMKKDFRSSVLKICSFLEKELSEEDVDAVVRQATFQKMKADPRANYEHIIKDELGTRNEMGSFLRKGVVGAWKHYLTVDQSERFDKIFHRNMKNIPLKFIWDINEE", "length": 293 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-030131-1135", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1135#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-722", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-722#orthology", "database": "AGR" }, { "id": "MGI:1931469", "url": "https://alliancegenome.org/gene/MGI:1931469#orthology", "database": "AGR" }, { "id": "FB:FBgn0034887", "url": "https://alliancegenome.org/gene/FB:FBgn0034887#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O43704-1", "protein_name": "Sulfotransferase 1B1", "gene_name": "SULT1B1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLSPKDILRKDLKLVHGYPMTCAFASNWEKIEQFHSRPDDIVIATYPKSGTTWVSEIIDMILNDGDIEKCKRGFITEKVPMLEMTLPGLRTSGIEQLEKNPSPRIVKTHLPTDLLPKSFWENNCKMIYLARNAKDVSVSYYHFDLMNNLQPFPGTWEEYLEKFLTGKVAYGSWFTHVKNWWKKKEEHPILFLYYEDMKENPKEEIKKIIRFLEKNLNDEILDRIIHHTSFEVMKDNPLVNYTHLPTTVMDHSKSPFMRKGTAGDWKNYFTVAQNEKFDAIYETEMSKTALQFRTEI", "length": 296 }, "evidence": [ { "id": "HGNC:17845", "url": "https://alliancegenome.org/gene/HGNC:17845#orthology", "database": "AGR" }, { "id": "MGI:2136282", "url": "https://alliancegenome.org/gene/MGI:2136282#orthology", "database": "AGR" }, { "id": "RGD:708534", "url": "https://alliancegenome.org/gene/RGD:708534#orthology", "database": "AGR" }, { "id": "FB:FBgn0034887", "url": "https://alliancegenome.org/gene/FB:FBgn0034887#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O75897-1", "protein_name": "Sulfotransferase 1C4", "gene_name": "SULT1C4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALHDMEDFTFDGTKRLSVNYVKGILQPTDTCDIWDKIWNFQAKPDDLLISTYPKAGTTWTQEIVELIQNEGDVEKSKRAPTHQRFPFLEMKIPSLGSGLEQAHAMPSPRILKTHLPFHLLPPSLLEKNCKIIYVARNPKDNMVSYYHFQRMNKALPAPGTWEEYFETFLAGKVCWGSWHEHVKGWWEAKDKHRILYLFYEDMKKNPKHEIQKLAEFIGKKLDDKVLDKIVHYTSFDVMKQNPMANYSSIPAEIMDHSISPFMRKGAVGDWKKHFTVAQNERFDEDYKKKMTDTRLTFHFQF", "length": 302 }, "evidence": [ { "id": "HGNC:11457", "url": "https://alliancegenome.org/gene/HGNC:11457#orthology", "database": "AGR" }, { "id": "MGI:102928", "url": "https://alliancegenome.org/gene/MGI:102928#orthology", "database": "AGR" }, { "id": "FB:FBgn0034887", "url": "https://alliancegenome.org/gene/FB:FBgn0034887#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0CC03-1", "protein_name": "Sulfotransferase 6B1", "gene_name": "Sult6b1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADKSKFIDYIDDALEKSKETTLSQLFLTYQGIPYPVTMCTQETFRALDAFEARSDDVLLASYPKCGSNWILHIVSELIFAVSKKKYACPEFPVLECGDAEKYQRMKLFPSPRILTTHLHYDKLPQSIFKNKAKILVIFRNPKDTAVSFFHFHNDVPDIPSYASWDEFFRQFIKGQVSWGSYFDFAINWNKHIDDENVKFILYEDLKENLVVGIKQISEFLGFSLTDEQIETISTQSTFLAMRANSQETHGAIGPFLFRKGEVGDWKRLFNETQNQEMDERFKECLAGTSLGDKLKYEAYCLA", "length": 303 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050417-228", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-228#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0DMM9-1", "protein_name": "Sulfotransferase 1A3", "gene_name": "SULT1A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MELIQDTSRPPLEYVKGVPLIKYFAEALGPLQSFQARPDDLLINTYPKSGTTWVSQILDMIYQGGDLEKCNRAPIYVRVPFLEVNDPGEPSGLETLKDTPPPRLIKSHLPLALLPQTLLDQKVKVVYVARNPKDVAVSYYHFHRMEKAHPEPGTWDSFLEKFMAGEVSYGSWYQHVQEWWELSRTHPVLYLFYEDMKENPKREIQKILEFVGRSLPEETMDFMVQHTSFKEMKKNPMTNYTTVPQELMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRSEL", "length": 295 }, "evidence": [ { "id": "HGNC:30004", "url": "https://alliancegenome.org/gene/HGNC:30004#orthology", "database": "AGR" }, { "id": "HGNC:11455", "url": "https://alliancegenome.org/gene/HGNC:11455#orthology", "database": "AGR" }, { "id": "RGD:3767", "url": "https://alliancegenome.org/gene/RGD:3767#orthology", "database": "AGR" }, { "id": "FB:FBgn0034887", "url": "https://alliancegenome.org/gene/FB:FBgn0034887#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P15709-1", "protein_name": "Sulfotransferase 2A1", "gene_name": "Sult2a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPDYTWFEGIPFHAFGISKETLQNVCNKFVVKDEDLILLAYPKSGTNWLIEIVCLIQTKGDPKWIQSVTIWDRSPWIETDLGYDMLIKKKGPRLITSHLPMHLFSKSLFSSKAKVIYLVRNPRDVLVSGYYFWGNSTLAKKPDSLGTYVEWFLKGNVLYGSWFEHIRAWLSMREWDNFLLLYYEDMKKDTMGTIKKICDFLGKKLEPDELDLVLKYSSFQVMKENDMSNYSLLMKKSIFTGIGLMRKGTVGDWKNHFTVSQAEAFDKVFQEKMAGFPPGMFPWE", "length": 284 }, "evidence": [ { "id": "RGD:3727", "url": "https://alliancegenome.org/gene/RGD:3727#orthology", "database": "AGR" }, { "id": "HGNC:11458", "url": "https://alliancegenome.org/gene/HGNC:11458#orthology", "database": "AGR" }, { "id": "MGI:3648915", "url": "https://alliancegenome.org/gene/MGI:3648915#orthology", "database": "AGR" }, { "id": "MGI:1924221", "url": "https://alliancegenome.org/gene/MGI:1924221#orthology", "database": "AGR" }, { "id": "RGD:621337", "url": "https://alliancegenome.org/gene/RGD:621337#orthology", "database": "AGR" }, { "id": "RGD:1306542", "url": "https://alliancegenome.org/gene/RGD:1306542#orthology", "database": "AGR" }, { "id": "FB:FBgn0034887", "url": "https://alliancegenome.org/gene/FB:FBgn0034887#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P17988-1", "protein_name": "Sulfotransferase 1A1", "gene_name": "Sult1a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEFSRPPLVHVKGIPLIKYFAETIGPLQNFTAWPDDLLISTYPKSGTTWMSEILDMIYQGGKLEKCGRAPIYARVPFLEFKCPGVPSGLETLEETPAPRLLKTHLPLSLLPQSLLDQKVKVIYIARNAKDVVVSYYNFYNMAKLHPDPGTWDSFLENFMDGEVSYGSWYQHVKEWWELRHTHPVLYLFYEDIKENPKREIKKILEFLGRSLPEETVDSIVHHTSFKKMKENCMTNYTTIPTEIMDHNVSPFMRKGTTGDWKNTFTVAQNERFDAHYAKTMTDCDFKFRCEL", "length": 291 }, "evidence": [ { "id": "HGNC:11453", "url": "https://alliancegenome.org/gene/HGNC:11453#orthology", "database": "AGR" }, { "id": "HGNC:11454", "url": "https://alliancegenome.org/gene/HGNC:11454#orthology", "database": "AGR" }, { "id": "HGNC:30004", "url": "https://alliancegenome.org/gene/HGNC:30004#orthology", "database": "AGR" }, { "id": "HGNC:11455", "url": "https://alliancegenome.org/gene/HGNC:11455#orthology", "database": "AGR" }, { "id": "RGD:3767", "url": "https://alliancegenome.org/gene/RGD:3767#orthology", "database": "AGR" }, { "id": "FB:FBgn0034887", "url": "https://alliancegenome.org/gene/FB:FBgn0034887#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P49888-1", "protein_name": "Sulfotransferase 1E1", "gene_name": "SULT1E1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNSELDYYEKFEEVHGILMYKDFVKYWDNVEAFQARPDDLVIATYPKSGTTWVSEIVYMIYKEGDVEKCKEDVIFNRIPFLECRKENLMNGVKQLDEMNSPRIVKTHLPPELLPASFWEKDCKIIYLCRNAKDVAVSFYYFFLMVAGHPNPGSFPEFVEKFMQGQVPYGSWYKHVKSWWEKGKSPRVLFLFYEDLKEDIRKEVIKLIHFLERKPSEELVDRIIHHTSFQEMKNNPSTNYTTLPDEIMNQKLSPFMRKGITGDWKNHFTVALNEKFDKHYEQQMKESTLKFRTEI", "length": 294 }, "evidence": [ { "id": "HGNC:11377", "url": "https://alliancegenome.org/gene/HGNC:11377#orthology", "database": "AGR" }, { "id": "MGI:98431", "url": "https://alliancegenome.org/gene/MGI:98431#orthology", "database": "AGR" }, { "id": "RGD:3776", "url": "https://alliancegenome.org/gene/RGD:3776#orthology", "database": "AGR" }, { "id": "FB:FBgn0034887", "url": "https://alliancegenome.org/gene/FB:FBgn0034887#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P49891-1", "protein_name": "Sulfotransferase 1E1", "gene_name": "Sult1e1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METSMPEYYEVFGEFRGVLMDKRFTKYWEDVEMFLARPDDLVIATYPKSGTTWISEVVYMIYKEGDVEKCKEDAIFNRIPYLECRNEDLINGIKQLKEKESPRIVKTHLPPKLLPASFWEKNCKMIYLCRNAKDVAVSYYYFLLMITSYPNPKSFSEFVEKFMQGQVPYGSWYDHVKAWWEKSKNSRVLFMFYEDMKEDIRREVVKLIEFLERKPSAELVDRIIQHTSFQEMKNNPSTNYTMMPEEMMNQKVSPFMRKGIIGDWKNHFPEALRERFDEHYKQQMKDCTVKFRMEL", "length": 295 }, "evidence": [ { "id": "HGNC:11377", "url": "https://alliancegenome.org/gene/HGNC:11377#orthology", "database": "AGR" }, { "id": "MGI:98431", "url": "https://alliancegenome.org/gene/MGI:98431#orthology", "database": "AGR" }, { "id": "RGD:3776", "url": "https://alliancegenome.org/gene/RGD:3776#orthology", "database": "AGR" }, { "id": "FB:FBgn0034887", "url": "https://alliancegenome.org/gene/FB:FBgn0034887#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P50225-1", "protein_name": "Sulfotransferase 1A1", "gene_name": "SULT1A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MELIQDTSRPPLEYVKGVPLIKYFAEALGPLQSFQARPDDLLISTYPKSGTTWVSQILDMIYQGGDLEKCHRAPIFMRVPFLEFKAPGIPSGMETLKDTPAPRLLKTHLPLALLPQTLLDQKVKVVYVARNAKDVAVSYYHFYHMAKVHPEPGTWDSFLEKFMVGEVSYGSWYQHVQEWWELSRTHPVLYLFYEDMKENPKREIQKILEFVGRSLPEETVDFVVQHTSFKEMKKNPMTNYTTVPQEFMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRSEL", "length": 295 }, "evidence": [ { "id": "HGNC:11453", "url": "https://alliancegenome.org/gene/HGNC:11453#orthology", "database": "AGR" }, { "id": "RGD:3767", "url": "https://alliancegenome.org/gene/RGD:3767#orthology", "database": "AGR" }, { "id": "FB:FBgn0034887", "url": "https://alliancegenome.org/gene/FB:FBgn0034887#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P50226-1", "protein_name": "Sulfotransferase 1A2", "gene_name": "SULT1A2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MELIQDISRPPLEYVKGVPLIKYFAEALGPLQSFQARPDDLLISTYPKSGTTWVSQILDMIYQGGDLEKCHRAPIFMRVPFLEFKVPGIPSGMETLKNTPAPRLLKTHLPLALLPQTLLDQKVKVVYVARNAKDVAVSYYHFYHMAKVYPHPGTWESFLEKFMAGEVSYGSWYQHVQEWWELSRTHPVLYLFYEDMKENPKREIQKILEFVGRSLPEETVDLMVEHTSFKEMKKNPMTNYTTVRREFMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAKKMAGCSLSFRSEL", "length": 295 }, "evidence": [ { "id": "HGNC:11454", "url": "https://alliancegenome.org/gene/HGNC:11454#orthology", "database": "AGR" }, { "id": "RGD:3767", "url": "https://alliancegenome.org/gene/RGD:3767#orthology", "database": "AGR" }, { "id": "FB:FBgn0034887", "url": "https://alliancegenome.org/gene/FB:FBgn0034887#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P50236-1", "protein_name": "Sulfotransferase 2A2", "gene_name": "Sult2a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMSDYNWFEGIPFPAISYQREILEDIRNKFVVKEEDLLILTYPKSGTNWLNEIVCLIQTKGDPKWIQTVPIWDRSPWIETEIGYSAIINKEGPRLITSHLPIHLFSKSFFSSKAKAIYLMRNPRDILVSGYFFWGNTNLVKNPGSLGTYFEWFLQGNVLFGSWFEHVRGWLSMREWDNFLVLYYEDMKKDTKGTIKKICDFLGKNLGPDELDLVLKYSSFQAMKENNMSNYSLIKEDRVTNGLKLMRKGTTGDWKNHFTVAQAEAFDKVFQEKMAGFPPGMFPWE", "length": 285 }, "evidence": [ { "id": "HGNC:11458", "url": "https://alliancegenome.org/gene/HGNC:11458#orthology", "database": "AGR" }, { "id": "MGI:107550", "url": "https://alliancegenome.org/gene/MGI:107550#orthology", "database": "AGR" }, { "id": "FB:FBgn0034887", "url": "https://alliancegenome.org/gene/FB:FBgn0034887#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P50237-1", "protein_name": "Sulfotransferase 1C1", "gene_name": "Sult1c1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLEKMKDLHLGEQDLQPETREVNGILMSKLMSDNWDKIWNFQAKPDDLLIATYAKAGTTWTQEIVDMIQNDGDVQKCQRANTYDRHPFIEWTLPSPLNSGLDLANKMPSPRTLKTHLPVHMLPPSFWKENSKIIYVARNAKDCLVSYYYFSRMNKMLPDPGTLGEYIEQFKAGKVLWGSWYDHVKGWWDVKDQHRILYLFYEDMKEDPKREIKKIAKFLEKDISEEVLNKIIYHTSFDVMKENPMANYTTLPSSIMDHSISPFMRKGMPGDWKNYFTVAQSEDFDEDYRRKMAGSNITFRTEI", "length": 304 }, "evidence": [ { "id": "HGNC:33543", "url": "https://alliancegenome.org/gene/HGNC:33543#orthology", "database": "AGR" }, { "id": "MGI:102928", "url": "https://alliancegenome.org/gene/MGI:102928#orthology", "database": "AGR" }, { "id": "RGD:3768", "url": "https://alliancegenome.org/gene/RGD:3768#orthology", "database": "AGR" }, { "id": "FB:FBgn0034887", "url": "https://alliancegenome.org/gene/FB:FBgn0034887#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P52840-1", "protein_name": "Sulfotransferase 1A1", "gene_name": "Sult1a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPLRKPLVPVKGIPLIKYFAETMEQLQNFTAWPDDVLISTYPKSGTNWMSEIMDMIYQGGKLDKCGRAPVYARIPFLEFSCPGVPPGLETLKETPAPRIIKTHLPLSLLPQSLLDQKIKVIYVARNAKDVVVSYYNFYKMAKLHPDPGTWESFLENFMDGKVSYGSWYQHVKEWWELRRTHPVLYLFYEDMKENPKREIKKILEFLGRSLPEETVDLIVHHTSFKKMKENPMANYTTIPTEVMDHTIYPFMRKGTIGDWKNTFTVAQSEHFDAHYAKLMTGCDFTFRCQI", "length": 291 }, "evidence": [ { "id": "HGNC:11453", "url": "https://alliancegenome.org/gene/HGNC:11453#orthology", "database": "AGR" }, { "id": "HGNC:11454", "url": "https://alliancegenome.org/gene/HGNC:11454#orthology", "database": "AGR" }, { "id": "HGNC:30004", "url": "https://alliancegenome.org/gene/HGNC:30004#orthology", "database": "AGR" }, { "id": "HGNC:11455", "url": "https://alliancegenome.org/gene/HGNC:11455#orthology", "database": "AGR" }, { "id": "RGD:3767", "url": "https://alliancegenome.org/gene/RGD:3767#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P52843-1", "protein_name": "Sulfotransferase 2A1", "gene_name": "Sult2a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMSDYNWFEGIPFPAISYQREILEDIRNKFVVKEEDLLILTYPKSGTNWLIEIVCLIQTKGDPKWIQTVPIWNRSPWIETDIGYSALINKEGPRLITSHLPIHLFSKSFFSSKAKAIYLVRNPRDILVSGYFFWGNTNLVKNPGSLGTYFEWFLKGNVLFGSWFEHVRGWLSMREWDNFLVLYYEDIKKDTKGTIKKICDFLGKNLGPDELDLVLKYSSFQAMKENNMSNFSLIKEDQVTNGLKLMRKGTIGDWKNHFTVAQAEAFDKVFQEKMAGFPPGIFPWE", "length": 285 }, "evidence": [ { "id": "HGNC:11458", "url": "https://alliancegenome.org/gene/HGNC:11458#orthology", "database": "AGR" }, { "id": "MGI:98430", "url": "https://alliancegenome.org/gene/MGI:98430#orthology", "database": "AGR" }, { "id": "FB:FBgn0034887", "url": "https://alliancegenome.org/gene/FB:FBgn0034887#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P52844-1", "protein_name": "Sulfotransferase 1E1", "gene_name": "Sult1e1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METSMPEYYEVFGDFHGVLMDKLFTKYWEDVETFSARPDDLLVVTYPKSGSTWIGEIVDMIYKEGDVEKCKEDAIFNRIPYLECRNEDLINGIKQLKEKESPRIVKTHLPAKLLPASFWEKNCKIIYLCRNAKDVVVSYYYFFLIIKSYPNPKSFSEFVEKFMEGQVPYGSWYDHVKSWWEKSKNSRVLFMFYEDMKEDIRREVVKLIEFLERDPLAELVDKIIQHTSFQEMKNNPCTNYSMLPETMIDLKVSPFMRKGIVGDWRNHFPEALRERFEEHYQRHMKDCPVKFRAEL", "length": 295 }, "evidence": [ { "id": "HGNC:11377", "url": "https://alliancegenome.org/gene/HGNC:11377#orthology", "database": "AGR" }, { "id": "MGI:98431", "url": "https://alliancegenome.org/gene/MGI:98431#orthology", "database": "AGR" }, { "id": "RGD:3776", "url": "https://alliancegenome.org/gene/RGD:3776#orthology", "database": "AGR" }, { "id": "FB:FBgn0034887", "url": "https://alliancegenome.org/gene/FB:FBgn0034887#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P52847-1", "protein_name": "Sulfotransferase 1B1", "gene_name": "Sult1b1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGTAEDVFRKDLKIIHGYPMVYAFALGWEKIEEFQSRPCDIVIPTYPKSGTTWLSEIVDMVLNDGNVEKCKRDVITSKVPMLEQNVPGARRSGVELLKKTPSPRIIKTHLPIDLLPKSFWDNKCKMIYLARNGKDVAVSYYHFDLMNNIQPLPGTWEEYLEKFLAGNVAYGSWFDHVKSWWEKREGHPILFLYYEDLKKNPKKEIKKIANFLDKTLDEHTLERIVHHTSFEVMKDNPLVNYTHLPTEIMDHSKSPFMRKGVVGDWKNYFTMTQSEKFDAIYKKKLSGTTLEFCTDIQSA", "length": 299 }, "evidence": [ { "id": "HGNC:17845", "url": "https://alliancegenome.org/gene/HGNC:17845#orthology", "database": "AGR" }, { "id": "MGI:2136282", "url": "https://alliancegenome.org/gene/MGI:2136282#orthology", "database": "AGR" }, { "id": "RGD:708534", "url": "https://alliancegenome.org/gene/RGD:708534#orthology", "database": "AGR" }, { "id": "FB:FBgn0034887", "url": "https://alliancegenome.org/gene/FB:FBgn0034887#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q06520-1", "protein_name": "Sulfotransferase 2A1", "gene_name": "SULT2A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSDDFLWFEGIAFPTMGFRSETLRKVRDEFVIRDEDVIILTYPKSGTNWLAEILCLMHSKGDAKWIQSVPIWERSPWVESEIGYTALSETESPRLFSSHLPIQLFPKSFFSSKAKVIYLMRNPRDVLVSGYFFWKNMKFIKKPKSWEEYFEWFCQGTVLYGSWFDHIHGWMPMREEKNFLLLSYEELKQDTGRTIEKICQFLGKTLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVVDKAQLLRKGVSGDWKNHFTVAQAEDFDKLFQEKMADLPRELFPWE", "length": 285 }, "evidence": [ { "id": "RGD:3727", "url": "https://alliancegenome.org/gene/RGD:3727#orthology", "database": "AGR" }, { "id": "HGNC:11458", "url": "https://alliancegenome.org/gene/HGNC:11458#orthology", "database": "AGR" }, { "id": "MGI:3645854", "url": "https://alliancegenome.org/gene/MGI:3645854#orthology", "database": "AGR" }, { "id": "MGI:3645873", "url": "https://alliancegenome.org/gene/MGI:3645873#orthology", "database": "AGR" }, { "id": "MGI:3648915", "url": "https://alliancegenome.org/gene/MGI:3648915#orthology", "database": "AGR" }, { "id": "MGI:107550", "url": "https://alliancegenome.org/gene/MGI:107550#orthology", "database": "AGR" }, { "id": "MGI:3645246", "url": "https://alliancegenome.org/gene/MGI:3645246#orthology", "database": "AGR" }, { "id": "MGI:98430", "url": "https://alliancegenome.org/gene/MGI:98430#orthology", "database": "AGR" }, { "id": "MGI:3648378", "url": "https://alliancegenome.org/gene/MGI:3648378#orthology", "database": "AGR" }, { "id": "MGI:1924221", "url": "https://alliancegenome.org/gene/MGI:1924221#orthology", "database": "AGR" }, { "id": "RGD:621337", "url": "https://alliancegenome.org/gene/RGD:621337#orthology", "database": "AGR" }, { "id": "RGD:1306542", "url": "https://alliancegenome.org/gene/RGD:1306542#orthology", "database": "AGR" }, { "id": "FB:FBgn0034887", "url": "https://alliancegenome.org/gene/FB:FBgn0034887#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q1L873-1", "protein_name": "Sulfotransferase", "gene_name": "sult3st5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAQEECKMISDKLLKYKGTVLTLEPSYDITPEYIDSIQDFETRDDDVFVVTFPKSGTVWTQRIITLIYEEDFPEKAKQITFEQMPWIEYREKGKDYSTRPSPRLFCSHLLEPLMPKTLKRKGKVIYVMRNPKDVMVSYFHFSQKMKDLDSAKSYDEVLENFLTGCMVGGSWFDHVKGWVTSKDKYNILILTYEEMIKDLRSVIVKICKFVGKNLSDAAIDKVVERATFKQMKVDPVANYESLPVDIIDQPKGAFMRKGTVGDWRNSLTVAQSECVDRALEERMKDVPLNLVWDITELRG", "length": 299 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-060503-722", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-722#orthology", "database": "AGR" }, { "id": "MGI:1931469", "url": "https://alliancegenome.org/gene/MGI:1931469#orthology", "database": "AGR" }, { "id": "MGI:3645972", "url": "https://alliancegenome.org/gene/MGI:3645972#orthology", "database": "AGR" }, { "id": "FB:FBgn0034887", "url": "https://alliancegenome.org/gene/FB:FBgn0034887#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q1L875-1", "protein_name": "Sulfotransferase", "gene_name": "sult3st2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAQEECKMISDKLLKYKGTVLTMETNHDITPEYIDSLQDFETRDDDVFVVTFPKSGTVWTQRIMTLIYEEDFPEKANEITYEQMPWIEYREKGKDYNARPSPRLFCSHLLEPLMPRALQKKGKVIYVMRNPKDVMVSYFHFSNKMKNLDSSENYDEILENFFTGCMIGGSWFDHVKGWVTSKDKYNILILTYEEMIKDLRSVIVKICKFVGKNLSDAAINKVVERTTFNQMKVDPVANYESLPQEVTDQPKGVFMRKGTVGDWKNSLTVAQSECVDRVFEERMKHVPLNLVWDIAELRG", "length": 299 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-030131-1135", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1135#orthology", "database": "AGR" }, { "id": "MGI:1931469", "url": "https://alliancegenome.org/gene/MGI:1931469#orthology", "database": "AGR" }, { "id": "MGI:3645972", "url": "https://alliancegenome.org/gene/MGI:3645972#orthology", "database": "AGR" }, { "id": "FB:FBgn0034887", "url": "https://alliancegenome.org/gene/FB:FBgn0034887#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q29YR5-1", "protein_name": "Sulfotransferase 2B1", "gene_name": "Sult2b1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDGPQPPALWGSLENRVSELSQKLQGEYFRYKGIPFPVGMYTPESLSLAENTSNVRDDDIFIVTYPKSGTNWMIEIICLILKDGDPSWIRSEPIWQRAPWCETTISAFSLPERPSPRLMCSHLPIELFTKAAFSSKAKVIYLGRNPRDVVVSLYYYSKIAVQLKDPGTPEQFLQNFLKGEVQFGSWFDHIKGWIRMRGRENFLFITYEELQQDLRGSVQLICEFLGRPLGEEALSSVVAHSAFAAMKANNMSNYTLLPASLLDHRQGAFLRKGISGDWKNHFTVAQSETFDQVYREQMHGLPSFPWDRSAEDGSPDGETEPSPSPSPGLASDDPNPGSSQ", "length": 340 }, "evidence": [ { "id": "HGNC:11459", "url": "https://alliancegenome.org/gene/HGNC:11459#orthology", "database": "AGR" }, { "id": "MGI:1926342", "url": "https://alliancegenome.org/gene/MGI:1926342#orthology", "database": "AGR" }, { "id": "RGD:1308882", "url": "https://alliancegenome.org/gene/RGD:1308882#orthology", "database": "AGR" }, { "id": "FB:FBgn0034887", "url": "https://alliancegenome.org/gene/FB:FBgn0034887#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3UZZ6-1", "protein_name": "Sulfotransferase 1 family member D1", "gene_name": "Sult1d1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDNKLDVFRRELVDVEGIPLFWSIAEHWSQVESFEARPDDILISTYPKSGTTWVSEILDLIYNNGDAEKCKRDAIYKRVPFMELIIPGITNGVEMLNNMPSPRIVKTHLPVQLLPSSFWKNDCKIIYVARNAKDVVVSYYYFYQMAKIHPEPGTWEEFLEKFMAGQVSFGPWYDHVKSWWEKRKEYRILYLFYEDMKENPKCEIQKILKFLEKDIPEEILNKILYHSSFSVMKENPSANYTTMMKEEMDHSVSPFMRKGISGDWKNQFTVAQYEKFEEDYVKKMEDSTLKFRSEI", "length": 295 }, "evidence": [ { "id": "MGI:1926341", "url": "https://alliancegenome.org/gene/MGI:1926341#orthology", "database": "AGR" }, { "id": "RGD:620491", "url": "https://alliancegenome.org/gene/RGD:620491#orthology", "database": "AGR" }, { "id": "FB:FBgn0034887", "url": "https://alliancegenome.org/gene/FB:FBgn0034887#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6IMI4-1", "protein_name": "Sulfotransferase 6B1", "gene_name": "SULT6B1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADKSKFIEYIDEALEKSKETALSHLFFTYQGIPYPITMCTSETFQALDTFEARHDDIVLASYPKCGSNWILHIVSELIYAVSKKKYKYPEFPVLECGDSEKYQRMKGFPSPRILATHLHYDKLPGSIFENKAKILVIFRNPKDTAVSFLHFHNDVPDIPSYGSWDEFFRQFMKGQVSWGRYFDFAINWNKHLDGDNVKFILYEDLKENLAAGIKQIAEFLGFFLTGEQIQTISVQSTFQAMRAKSQDTHGAVGPFLFRKGEVGDWKNLFSEIQNQEMDEKFKECLAGTSLGAKLKYESYCQG", "length": 303 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050417-228", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-228#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6IMI6-1", "protein_name": "Sulfotransferase 1C3", "gene_name": "SULT1C3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKIEKNAPTMEKKPELFNIMEVDGVPTLILSKEWWEKVCNFQAKPDDLILATYPKSGTTWMHEILDMILNDGDVEKCKRAQTLDRHAFLELKFPHKEKPDLEFVLEMSSPQLIKTHLPSHLIPPSIWKENCKIVYVARNPKDCLVSYYHFHRMASFMPDPQNLEEFYEKFMSGKVVGGSWFDHVKGWWAAKDMHRILYLFYEDIKKDPKREIEKILKFLEKDISEEILNKIIYHTSFDVMKQNPMTNYTTLPTSIMDHSISPFMRKGMPGDWKNYFTVAQNEEFDKDYQKKMAGSTLTFRTEI", "length": 304 }, "evidence": [ { "id": "HGNC:33543", "url": "https://alliancegenome.org/gene/HGNC:33543#orthology", "database": "AGR" }, { "id": "MGI:102928", "url": "https://alliancegenome.org/gene/MGI:102928#orthology", "database": "AGR" }, { "id": "RGD:3768", "url": "https://alliancegenome.org/gene/RGD:3768#orthology", "database": "AGR" }, { "id": "FB:FBgn0034887", "url": "https://alliancegenome.org/gene/FB:FBgn0034887#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6PH37-1", "protein_name": "Cytosolic sulfotransferase 1", "gene_name": "sult1st1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDIPDFSSISSRPTIFEFEGISMINHFTENWEKVKNFQARPDDILIATYPKAGTTWVSYILDLLYFGENAPEEHTSQPIYMRVPFLESCFKVIASGTELADNMTTSPRLIKTHLPVQLIPKSFWEQNSRVVYVARNAKDNVVSYFHFDRMNIVEPDPGDWNTFLHRFMDGKSVFGPWYDHVNGYWEKKQTYSNLLYLFYEDLVEDTGREVDRLCSFLGLSTSVSDREKITKDVQFDAMKQNKMTNYSTLPVMDFKISPFMRKGKVGDWKNHFTVAQNEQFDEVYKEKMKNATVKFRTEI", "length": 299 }, "evidence": [ { "id": "HGNC:11377", "url": "https://alliancegenome.org/gene/HGNC:11377#orthology", "database": "AGR" }, { "id": "HGNC:30004", "url": "https://alliancegenome.org/gene/HGNC:30004#orthology", "database": "AGR" }, { "id": "HGNC:11455", "url": "https://alliancegenome.org/gene/HGNC:11455#orthology", "database": "AGR" }, { "id": "MGI:98431", "url": "https://alliancegenome.org/gene/MGI:98431#orthology", "database": "AGR" }, { "id": "MGI:2136282", "url": "https://alliancegenome.org/gene/MGI:2136282#orthology", "database": "AGR" }, { "id": "RGD:3767", "url": "https://alliancegenome.org/gene/RGD:3767#orthology", "database": "AGR" }, { "id": "RGD:708534", "url": "https://alliancegenome.org/gene/RGD:708534#orthology", "database": "AGR" }, { "id": "RGD:3776", "url": "https://alliancegenome.org/gene/RGD:3776#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q7T2V2-1", "protein_name": "Cytosolic sulfotransferase 3", "gene_name": "sult1st3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEISDFSSMKLNSRPELIDFEGISMIHYFTDNWEKVKNFQARPDDILIATYPKAGTTWVSYILDLLYFGNESPERQTSQPIYMRVPFLEACFEGIPFGTELADNLPTSPRLIKTHLPVQLVPKSFWEQNSKVVYVARNAKDNAVSYFHFDRMNMGQPEPGDWNTFLQKFMEGRNVFGPWYDHVNGYWKKKQTYSNILYMFYEDMVENTGREVERLCSFLGLSTSAAERERITKGVQFDAMKQNKMTNYSTIPVMDFKISPFMRKGKVGDWRNHFTVAQNEQFDEVYKQKMKNTTVKFRTEL", "length": 301 }, "evidence": [ { "id": "HGNC:11377", "url": "https://alliancegenome.org/gene/HGNC:11377#orthology", "database": "AGR" }, { "id": "MGI:98431", "url": "https://alliancegenome.org/gene/MGI:98431#orthology", "database": "AGR" }, { "id": "MGI:2136282", "url": "https://alliancegenome.org/gene/MGI:2136282#orthology", "database": "AGR" }, { "id": "RGD:3767", "url": "https://alliancegenome.org/gene/RGD:3767#orthology", "database": "AGR" }, { "id": "RGD:708534", "url": "https://alliancegenome.org/gene/RGD:708534#orthology", "database": "AGR" }, { "id": "RGD:3776", "url": "https://alliancegenome.org/gene/RGD:3776#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q7ZUS4-1", "protein_name": "Cytosolic sulfotransferase 2", "gene_name": "sult1st2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEIPDFSSMKLDSRPELIDFEGVSMTRYFTDNWEKVKNFQARPDDILIATYPKAGTTWVSYILDLLYFGNESPERQTSQPIYMRVPFLEMCFQGLPLGTELADTLPTSPRPIKTHLPVQLVPKSFWEQNSKVVYVARNAKDNAVSYFHFDRMNMGQPEPGDWNTFLQKFMDGRNVFGPWYDHVNGYWKKKQTYSNILYMFYEDMVEDTGREVARLCSFLGLSTSATERERITKGVQFDVMKQNKMTNYSTLPVMDFKISPFMRKGKVGDWRNHFTVAQNEQFDEVYKQKMKNTTVKFRTEI", "length": 301 }, "evidence": [ { "id": "HGNC:11377", "url": "https://alliancegenome.org/gene/HGNC:11377#orthology", "database": "AGR" }, { "id": "MGI:98431", "url": "https://alliancegenome.org/gene/MGI:98431#orthology", "database": "AGR" }, { "id": "MGI:2136282", "url": "https://alliancegenome.org/gene/MGI:2136282#orthology", "database": "AGR" }, { "id": "RGD:3767", "url": "https://alliancegenome.org/gene/RGD:3767#orthology", "database": "AGR" }, { "id": "RGD:708534", "url": "https://alliancegenome.org/gene/RGD:708534#orthology", "database": "AGR" }, { "id": "RGD:3776", "url": "https://alliancegenome.org/gene/RGD:3776#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q80VR3-1", "protein_name": "Sulfotransferase 1C1", "gene_name": "Sult1c1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPLEKLKDLHLDEQNMQPETREVNGILMSKMMSENWDKIWNFQAKPDDLLIATYAKAGTTWTQEIVDMIQNDGDVQKCQRANTYDRHPFIEWTLPPPLNSGLDLANKMPSPRTLKTHLPVQMLPPSFWKENSKIIYVARNAKDCLVSYYYFSRMNKMLPDPGTLGEYIETFKAGKVLWGSWYDHVKGWWDVKDKHRILYLFYEDMKEDPKREIKKIVKFLEKDISEEVLNKIIHHTSFDVMKQNPMANYTTLPSSIMDHSISPFMRKGMPGDWKNYFTVAQSEDFDEDYRKKMAGSTITFRTEI", "length": 304 }, "evidence": [ { "id": "HGNC:33543", "url": "https://alliancegenome.org/gene/HGNC:33543#orthology", "database": "AGR" }, { "id": "HGNC:11457", "url": "https://alliancegenome.org/gene/HGNC:11457#orthology", "database": "AGR" }, { "id": "MGI:102928", "url": "https://alliancegenome.org/gene/MGI:102928#orthology", "database": "AGR" }, { "id": "RGD:3768", "url": "https://alliancegenome.org/gene/RGD:3768#orthology", "database": "AGR" }, { "id": "FB:FBgn0034887", "url": "https://alliancegenome.org/gene/FB:FBgn0034887#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8BGL3-1", "protein_name": "Sulfotransferase 2A8", "gene_name": "Sult2a8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTDEFLWIEGIPFPTVYYSQEIIREVRDRFVVRDEDTIIVTYPKSGTHWLNEIVCLILTKGDPTWVQSTIANERTPWIEFENNYRILNSKEGPRLMASLLPIQLFPKSFFSSKAKVIYLIRNPRDVLVSGYHYFNALKQGKEQVPWKIYFENFLQGKSYFGSWFEHACGWISLRKRENILVLSYEQLKKDTRNTIKKICEFLGENLESGELELVLKNISFQIMKERMISQSCLSNIEKHEFIMRKGITGDWKNHFTVAQAEAFDKAFQEKAADFPQELFSWE", "length": 282 }, "evidence": [ { "id": "HGNC:11458", "url": "https://alliancegenome.org/gene/HGNC:11458#orthology", "database": "AGR" }, { "id": "MGI:1924221", "url": "https://alliancegenome.org/gene/MGI:1924221#orthology", "database": "AGR" }, { "id": "RGD:1306542", "url": "https://alliancegenome.org/gene/RGD:1306542#orthology", "database": "AGR" }, { "id": "FB:FBgn0034887", "url": "https://alliancegenome.org/gene/FB:FBgn0034887#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9D939-1", "protein_name": "Sulfotransferase 1C2", "gene_name": "Sult1c2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALTPELSRQTKLKEVAGIPLQAPTVDNWRQIQTFEAKPDDLLICTYPKSGTTWIQEIVDMIEQNGDVEKCRRTIIQHRHPFIEWARPPQPSGVDKANEMPAPRILRTHLPTQLLPPSFWTNNCKFLYVARNAKDCMVSYYHFYRMSQVLPEPGTWDEYFETFINGKVSWGSWFDHVKGWWEIRDKYQILFLFYEDMKRNPKHEIQKVMQFMGKNLDEDVVDKIVLETSFEKMKENPMTNRSTAPKSILDQSISPFMRKGTVGDWKNHFTVAQNERFDEIYKQKMGRTSLNFSMEL", "length": 296 }, "evidence": [ { "id": "MGI:1916333", "url": "https://alliancegenome.org/gene/MGI:1916333#orthology", "database": "AGR" }, { "id": "RGD:621064", "url": "https://alliancegenome.org/gene/RGD:621064#orthology", "database": "AGR" }, { "id": "RGD:1305885", "url": "https://alliancegenome.org/gene/RGD:1305885#orthology", "database": "AGR" }, { "id": "FB:FBgn0034887", "url": "https://alliancegenome.org/gene/FB:FBgn0034887#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9QWG7-1", "protein_name": "Sulfotransferase 1B1", "gene_name": "Sult1b1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSASEDVWRKDLKMIHGYPMIYAFALNWERIEEFQSTPGDIVITTYPKSGTTWLSEIVDMVLNDGNVEKCKRDVITSKVPMLELSVPGIRISGVELLKKTPSPRIIKTHLPIDLLPKSFWENKCKMIYLARNGKDVAVSYYHFDLMNSINPLPGTWEEYLEKFLAGNVAYGSWFDHVKSWWEKREEHPLLYLYYEELKQNPKKEIKKIASFLDKTLDEEALDRIVHHTSFEMMKENPLVNYTHLPTAMMDHSKSPFMRKGIVGDWKNYFTMTQTEQFDAVYKKKMSGTTLEFCTDIQSA", "length": 299 }, "evidence": [ { "id": "HGNC:17845", "url": "https://alliancegenome.org/gene/HGNC:17845#orthology", "database": "AGR" }, { "id": "MGI:2136282", "url": "https://alliancegenome.org/gene/MGI:2136282#orthology", "database": "AGR" }, { "id": "RGD:708534", "url": "https://alliancegenome.org/gene/RGD:708534#orthology", "database": "AGR" }, { "id": "FB:FBgn0034887", "url": "https://alliancegenome.org/gene/FB:FBgn0034887#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VHH0-1", "protein_name": "Sulfotransferase 2, isoform B", "gene_name": "St2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MQLIYRELEEDILRRTNAVFPVQNCFVEVLPDQFIIPRKYVELGESIRSLPVYQDDVWMVSYPRTGSTWAQEMVWLLGHQLDYVAAEQDLRLRSPLIELSALFSIDHHETVAQKFGNTVDLVRNLPRPRFARSHLPWPLLPEQFETVKPRIVYTARNPKDLCVSYYHYFKLLHGMNGDFEQFVDLFLEGHTPMGSYWRHVLPFWKRSQDDNVLFIKYEDMVKDLPSVVRRCARFLGVQSLLDVSTLQKLCDHLTFDKMRANKAVNLEKLLPESSSKFIRNGKIGDWRNHMGNEMSERFDEWTERHMRGSGLNFDYV", "length": 316 }, "evidence": [ { "id": "HGNC:11458", "url": "https://alliancegenome.org/gene/HGNC:11458#orthology", "database": "AGR" }, { "id": "HGNC:11457", "url": "https://alliancegenome.org/gene/HGNC:11457#orthology", "database": "AGR" }, { "id": "MGI:1916333", "url": "https://alliancegenome.org/gene/MGI:1916333#orthology", "database": "AGR" }, { "id": "MGI:1924221", "url": "https://alliancegenome.org/gene/MGI:1924221#orthology", "database": "AGR" }, { "id": "RGD:3776", "url": "https://alliancegenome.org/gene/RGD:3776#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9WUW8-1", "protein_name": "Sulfotransferase 1C2", "gene_name": "Sult1c2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALAPELSRQTKLKEVAGIPLQAPTVDNWSQIQTFKAKPDDLLICTYPKSGTTWIQEIVDMIEQNGDVEKCQRTIIQHRHPFIEWARPPQPSGVDKANAMPAPRILRTHLPTQLLPPSFWTNNCKFLYVARNAKDCMVSYYHFYRMSQVLPDPGTWNEYFETFINGKVSWGSWFDHVKGWWEIRDRYQILFLFYEDMKRDPKREIQKVMQFMGKNLDEEVVDKIVLETSFEKMKENPMTNRSTVPKSVLDQSISPFMRKGTVGDWKNHFTVAQNDRFDEIYKQKMGGTSLNFCMEL", "length": 296 }, "evidence": [ { "id": "MGI:1916333", "url": "https://alliancegenome.org/gene/MGI:1916333#orthology", "database": "AGR" }, { "id": "RGD:621064", "url": "https://alliancegenome.org/gene/RGD:621064#orthology", "database": "AGR" }, { "id": "RGD:1305885", "url": "https://alliancegenome.org/gene/RGD:1305885#orthology", "database": "AGR" }, { "id": "FB:FBgn0034887", "url": "https://alliancegenome.org/gene/FB:FBgn0034887#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "sulfotransferase activity", "id": "GO:0008146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008146", "evidence": [ { "database": "UniProtKB", "id": "Q9W1L8", "url": "https://www.uniprot.org/uniprotkb/Q9W1L8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "sulfation", "id": "GO:0051923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051923", "evidence": [ { "database": "UniProtKB", "id": "Q9W1L8", "url": "https://www.uniprot.org/uniprotkb/Q9W1L8" } ], "pmid": "" }, { "name": "xenobiotic metabolic process", "id": "GO:0006805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006805", "evidence": [ { "database": "UniProtKB", "id": "Q9W1L8", "url": "https://www.uniprot.org/uniprotkb/Q9W1L8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9W1L8", "url": "https://www.uniprot.org/uniprotkb/Q9W1L8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9W1L8", "url": "https://www.uniprot.org/uniprotkb/Q9W1L8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 198, "end_pos": 200, "annotation": "n_glycosylation_sequon" }, { "start_pos": 331, "end_pos": 333, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9W1L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W1L8" }, { "id": "PF00685", "database": "Pfam", "url": 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Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1M5", "url": "https://www.uniprot.org/uniprotkb/Q9W1M5" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker 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Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W1M5", "url": "https://www.uniprot.org/uniprotkb/Q9W1M5" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W1M5", "url": "https://www.uniprot.org/uniprotkb/Q9W1M5" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1M5", "url": "https://www.uniprot.org/uniprotkb/Q9W1M5" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1M5", "url": "https://www.uniprot.org/uniprotkb/Q9W1M5" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, 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SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W1N8", "url": "https://www.uniprot.org/uniprotkb/Q9W1N8" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1N8", "url": "https://www.uniprot.org/uniprotkb/Q9W1N8" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1N8", "url": "https://www.uniprot.org/uniprotkb/Q9W1N8" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, 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Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1N9", "url": "https://www.uniprot.org/uniprotkb/Q9W1N9" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1N9", "url": "https://www.uniprot.org/uniprotkb/Q9W1N9" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W1N9", "url": "https://www.uniprot.org/uniprotkb/Q9W1N9" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W1N9", "url": "https://www.uniprot.org/uniprotkb/Q9W1N9" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W1N9", "url": "https://www.uniprot.org/uniprotkb/Q9W1N9" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1N9", "url": "https://www.uniprot.org/uniprotkb/Q9W1N9" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1N9", "url": "https://www.uniprot.org/uniprotkb/Q9W1N9" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W1T4", "url": "https://www.uniprot.org/uniprotkb/Q9W1T4" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W1T4", "url": "https://www.uniprot.org/uniprotkb/Q9W1T4" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1T4", "url": "https://www.uniprot.org/uniprotkb/Q9W1T4" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1T4", "url": "https://www.uniprot.org/uniprotkb/Q9W1T4" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W1T4", "url": "https://www.uniprot.org/uniprotkb/Q9W1T4" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W1T4", "url": "https://www.uniprot.org/uniprotkb/Q9W1T4" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W1T4", "url": "https://www.uniprot.org/uniprotkb/Q9W1T4" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1T4", "url": "https://www.uniprot.org/uniprotkb/Q9W1T4" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1T4", "url": "https://www.uniprot.org/uniprotkb/Q9W1T4" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W1T4", "url": "https://www.uniprot.org/uniprotkb/Q9W1T4" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W1T4", "url": "https://www.uniprot.org/uniprotkb/Q9W1T4" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG3162", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3162", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AB32T7Y9-1", "protein_name": "Splicing factor U2AF subunit", "gene_name": "u2af2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDFDEFERQLSENKQERDKENRHRRRSPSRSRSRERKRRSRERRSRERRGDSKERRHRRSDHTQNHPQENVSRSPHREKKKKIKKYWDVPPPGFEHITPMQYKAMQAAGQIPATALLPTMTPDGLAVTPTPVPVVGSQMTRQARRLYVGNIPFGITEESMMDFFNAQMRLGGLTQAPGNPVLAVQINQDKNFAFLEFRSVDETTQAMAFDGIIFQAQSLKIRRPHDYQPLPGMSENPSVYVPGVVSTVVPDSIHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDVNVNDQAIAGLNGMQLADKKLLVQRASVGAKNATMTSINETPVTLQVPGLTSNPMIQMGGIPTEVLCLMNMVAPEELIDDEEYEEIVEDVKEECSKYGQVKSIEIPRPVDGLDIPGTGKIFVEFTSVYDSQKAMQGLTGRKFANRVVVTKYCDPDAYHRRDFW", "length": 468 }, "evidence": [ { "id": "MGI:98886", "url": "https://alliancegenome.org/gene/MGI:98886#orthology", "database": "AGR" }, { "id": "HGNC:23156", "url": "https://alliancegenome.org/gene/HGNC:23156#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7F8Y4-1", "protein_name": "Splicing factor U2AF subunit", "gene_name": "u2af2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDFDEFERQLTENKQADRDKENKHHRRSGSRSRSRDRDRKRRSRDRDRERRGSRDRHGDSKDRRHRRSRSPHREKKKIKVKKYWDVPPPGFEHITPMQYKAMQAAGQIPATALLPTMTPEGLAVTPTPVPVVGSQMTRQARRLYVGNIPFGITEESMMDFFNAQMRLGGLTQAPGNPVLAVQINQDKNFAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPHDYQPLPGMSENPSVYVPGSLPVGVVSTVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDVNISDQAIAGLNGMQLGDKKLLVQRASVGSKNTTLTGINQTPVTLQVPGLMNSSVNQMGGIPTEVLCLMNMVAPEELLDDEEYEEIVEDVRDECSKYGQVKSIEIPRPVDGLDIPGTGKIFVEFMSVFDSQKAMQGLTGRKFANRVVVTKYCDPDAYHRRDFW", "length": 470 }, "evidence": [ { "id": "MGI:98886", "url": "https://alliancegenome.org/gene/MGI:98886#orthology", "database": "AGR" }, { "id": "HGNC:23156", "url": "https://alliancegenome.org/gene/HGNC:23156#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F2Z3T9-1", "protein_name": "Splicing factor U2AF subunit", "gene_name": "U2af2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSDFDEFERQLNENKQERDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRRRSKPLTRGAKEEHGGLIRSPRHEKKKKVRKYWDVPPPGFEHITPMQYKAMQAAGQIPATALLPTMTPDGLAVTPTPVPVVGSQMTRQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPVLAVQINQDKNFAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPHDYQPLPGMSENPSVYVPGVVSTVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTDQAIAGLNGMQLGDKKLLVQRASVGAKNATLVSLPSTINQTPVTLQVPGLMSSQVQMGGHPTEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVDGVEVPGCGKIFVEFTSVFDCQKAMQGLTGRKFANRVVVTKYCDPDSYHRRDFW", "length": 475 }, "evidence": [ { "id": "RGD:1310690", "url": "https://alliancegenome.org/gene/RGD:1310690#orthology", "database": "AGR" }, { "id": "MGI:98886", "url": "https://alliancegenome.org/gene/MGI:98886#orthology", "database": "AGR" }, { "id": "HGNC:23156", "url": "https://alliancegenome.org/gene/HGNC:23156#orthology", "database": "AGR" }, { "id": "FB:FBgn0034834", "url": "https://alliancegenome.org/gene/FB:FBgn0034834#orthology", "database": "AGR" }, { "id": "SGD:S000001557", "url": "https://alliancegenome.org/gene/SGD:S000001557#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P26368-1", "protein_name": "Splicing factor U2AF 65 kDa subunit", "gene_name": "U2AF2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSDFDEFERQLNENKQERDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRRRSKPLTRGAKEEHGGLIRSPRHEKKKKVRKYWDVPPPGFEHITPMQYKAMQAAGQIPATALLPTMTPDGLAVTPTPVPVVGSQMTRQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPVLAVQINQDKNFAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPHDYQPLPGMSENPSVYVPGVVSTVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTDQAIAGLNGMQLGDKKLLVQRASVGAKNATLVSPPSTINQTPVTLQVPGLMSSQVQMGGHPTEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVDGVEVPGCGKIFVEFTSVFDCQKAMQGLTGRKFANRVVVTKYCDPDSYHRRDFW", "length": 475 }, "evidence": [ { "id": "RGD:1310690", "url": "https://alliancegenome.org/gene/RGD:1310690#orthology", "database": "AGR" }, { "id": "MGI:98886", "url": "https://alliancegenome.org/gene/MGI:98886#orthology", "database": "AGR" }, { "id": "HGNC:23156", "url": "https://alliancegenome.org/gene/HGNC:23156#orthology", "database": "AGR" }, { "id": "FB:FBgn0034834", "url": "https://alliancegenome.org/gene/FB:FBgn0034834#orthology", "database": "AGR" }, { "id": "SGD:S000001557", "url": "https://alliancegenome.org/gene/SGD:S000001557#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P26369-1", "protein_name": "Splicing factor U2AF 65 kDa subunit", "gene_name": "U2af2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDFDEFERQLNENKQERDKENRHRKRSHSRSRSRDRKRRSRSRDRRNRDQRSASRDRRRRSKPLTRGAKEEHGGLIRSPRHEKKKKVRKYWDVPPPGFEHITPMQYKAMQAAGQIPATALLPTMTPDGLAVTPTPVPVVGSQMTRQARRLYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPVLAVQINQDKNFAFLEFRSVDETTQAMAFDGIIFQGQSLKIRRPHDYQPLPGMSENPSVYVPGVVSTVVPDSAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTDQAIAGLNGMQLGDKKLLVQRASVGAKNATLVSLPSTINQTPVTLQVPGLMSSQVQMGGHPTEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPVDGVEVPGCGKIFVEFTSVFDCQKAMQGLTGRKFANRVVVTKYCDPDSYHRRDFW", "length": 475 }, "evidence": [ { "id": "RGD:1310690", "url": "https://alliancegenome.org/gene/RGD:1310690#orthology", "database": "AGR" }, { "id": "MGI:98886", "url": "https://alliancegenome.org/gene/MGI:98886#orthology", "database": "AGR" }, { "id": "HGNC:23156", "url": "https://alliancegenome.org/gene/HGNC:23156#orthology", "database": "AGR" }, { "id": "FB:FBgn0034834", "url": "https://alliancegenome.org/gene/FB:FBgn0034834#orthology", "database": "AGR" }, { "id": "SGD:S000001557", "url": "https://alliancegenome.org/gene/SGD:S000001557#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P36084-1", "protein_name": "Splicing factor MUD2", "gene_name": "MUD2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MADEKRLEDLRSKIMESIGKSEKDVVPIENKRFNTDNAVIDTHFKRQKSDGELPKAPKSRNVSHSNNRGPSSIITMSTNRTTYEQTRAGPHRQSYRDASGRSYNRENRYSSHNTGPQWNNNPYNRQRDERRGRNERFDRRGRNGNGNYDRFNYQRKNEGSKFNGDRDKRQLQTNKYDMNYNSQNVMYPGSSFDSPAYYNMASSKANSRLVISGLSQSSDPSIVARLKDLLENFISGLQKTESNAEDFKISNFYIGEGRPDHIIVEFSSQICSTMVLACRSFFNAKLGTFDLKWRRPNDYVQQLDHLVDFCRGTVIALENLENIGEGEDYRMKELFSSLNVTNGTAKPLFYKCSSNTNNTGKESEFTKCILLSFEVVTQDILDKLKPYKWFKPNDGKISQVTSWITFQSLPNLVTQSVRVESRVLLLLNCLDPLDLKDETFITEIKETLKYSIAGADTIKICQPGVDYRLNFENLASGAGNIYIKFKTLEAAKHAMEELPGTQFNDRTVLCTYIDEDDFDMMEATQLS", "length": 527 }, "evidence": [ { "id": "RGD:1310690", "url": "https://alliancegenome.org/gene/RGD:1310690#orthology", "database": "AGR" }, { "id": "MGI:98886", "url": "https://alliancegenome.org/gene/MGI:98886#orthology", "database": "AGR" }, { "id": "HGNC:23156", "url": "https://alliancegenome.org/gene/HGNC:23156#orthology", "database": "AGR" }, { "id": "FB:FBgn0034834", "url": "https://alliancegenome.org/gene/FB:FBgn0034834#orthology", "database": "AGR" }, { "id": "SGD:S000001557", "url": "https://alliancegenome.org/gene/SGD:S000001557#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q24562-1", "protein_name": "Splicing factor U2AF 50 kDa subunit", "gene_name": "U2af50", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGYDDRERDRERRRHRSRSRDRHRERSRDRRHHRNSRRKPSLYWDVPPPGFEHITPMQYKAMQASGQIPASVVPDTPQTAVPVVGSTITRQARRLYVGNIPFGVTEEEMMEFFNQQMHLVGLAQAAGSPVLACQINLDKNFAFLEFRSIDETTQAMAFDGINLKGQSLKIRRPHDYQPMPGITDTPAIKPAVVSSGVISTVVPDSPHKIFIGGLPNYLNDDQVKELLLSFGKLRAFNLVKDAATGLSKGYAFCEYVDLSITDQSIAGLNGMQLGDKKLIVQRASVGAKNAQNAANTTQSVMLQVPGLSNVVTSGPPTEVLCLLNMVTPDELRDEEEYEDILEDIKEECTKYGVVRSVEIPRPIEGVEVPGCGKVFVEFNSVLDCQKAQQALTGRKFSDRVVVTSYFDPDKYHRREF", "length": 416 }, "evidence": [ { "id": "RGD:1310690", "url": "https://alliancegenome.org/gene/RGD:1310690#orthology", "database": "AGR" }, { "id": "MGI:98886", "url": "https://alliancegenome.org/gene/MGI:98886#orthology", "database": "AGR" }, { "id": "HGNC:23156", "url": "https://alliancegenome.org/gene/HGNC:23156#orthology", "database": "AGR" }, { "id": "SGD:S000001557", "url": "https://alliancegenome.org/gene/SGD:S000001557#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q9W1T4", "url": "https://www.uniprot.org/uniprotkb/Q9W1T4" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "Q9W1T4", "url": "https://www.uniprot.org/uniprotkb/Q9W1T4" } ], "pmid": "" }, { "name": "pre-mRNA 3'-splice site binding", "id": "GO:0030628", "url": 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"evidence": [ { "id": "NP_611761", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611761" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W1U2", "url": "https://www.uniprot.org/uniprotkb/Q9W1U2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG13544", "url": "https://www.uniprot.org/uniprotkb/Q9W1U2", "locus": { "chromosome": "2R", "start_pos": 23139080, "end_pos": 23140577, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0034826", "url": "https://www.ensemblgenomes.org/id/FBgn0034826" } ] } } ], "crossref": [ { "id": "FB:FBgn0034826", "url": "https://alliancegenome.org/gene/FB:FBgn0034826", "database": "AGR", "categories": [ "Protein Classification" ] }, { 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"https://www.uniprot.org/uniprotkb/Q9W1U2/entry#Q9W1U2-1", "sequence": { "sequence": "MFSGLIPMMQQTRRATVPLGGDSRSGNTESQIGSSKSSNCRLHLISRTGKLLLDYKQYKAARTIQNNWRKFYFRKYFKDLRKAVITIQRWWRGFSVRKNHFRYVENLLQKRVQDHHHRAATKIQALFRGWKSRRTIHDHSKLLRKQVCAAEDLLNCVAFKLHHLLRTFAIPGVYSLKNSNCMSRVEKLLASLHFRFHNGRVKTQLAKELADRGKDTETFKRSNKFSKVPFEGARYWSQCKPKCEAALKMSKNIERRMYRIIEIYDASQREAHAALVEKNRAYRKHKGLMQNIKKSAEKSKRDFCGDVIASMRRWKILVDNDLTVDKNIFKNPQNLERFVAEISQYANEFENCTCYCRIPVFTEIYCG", "length": 367, "header": "tr|Q9W1U2-1|Q9W1U2_DROME Isoform 1 of Spermatogenesis-associated protein 17 OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG13544 PE=4 SV=1 CANONICAL=Q9W1U2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W1U2", "url": "https://www.uniprot.org/uniprotkb/Q9W1U2" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W1U2", "url": "https://www.uniprot.org/uniprotkb/Q9W1U2" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1U2", "url": "https://www.uniprot.org/uniprotkb/Q9W1U2" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1U2", "url": "https://www.uniprot.org/uniprotkb/Q9W1U2" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W1U2", "url": "https://www.uniprot.org/uniprotkb/Q9W1U2" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W1U2", "url": "https://www.uniprot.org/uniprotkb/Q9W1U2" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W1U2", "url": "https://www.uniprot.org/uniprotkb/Q9W1U2" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1U2", "url": "https://www.uniprot.org/uniprotkb/Q9W1U2" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1U2", "url": "https://www.uniprot.org/uniprotkb/Q9W1U2" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W1U2", "url": "https://www.uniprot.org/uniprotkb/Q9W1U2" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W1U2", "url": "https://www.uniprot.org/uniprotkb/Q9W1U2" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG13544", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG13544", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9F2IDH0-1", "protein_name": "Spermatogenesis-associated protein 17", "gene_name": "Dmel\\CG31735", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPFFGSPGSTMEEDEDPSYESYFVEEDMESIIRPLAAKLTWTTVHLIDYKMFIAARRIQSFWRGYRVRKLLHLRWQSAIAIQRWWRGFRTRHILYEKVERRLQGIIHEHFHRAAIRIQALFRGWWVRKFIHDVRNLHRMQCTAAEDLINCIIHEMHHIKKTDSIPGVISLRNSVCRSKVEKLLTTMIFRFHNGRVLSMVANRMSQKEEYRRHFRDARFVTHIPYSGPNFDGLCYVREDDHIVLKEVPTDLRYSEIVTEYEESQLHEHLRETHLRFDLRKLQRQIDHINYQELHLKRKFCADVIDRMRKWTIWDSISANHKQNIYESRKNTQVFFRRAEHLMSDFYVSKAEDSYHVLSLSSST", "length": 362 }, "evidence": [ { "id": "HGNC:25184", "url": "https://alliancegenome.org/gene/HGNC:25184#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A0AC58HNY8-1", "protein_name": 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"GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9W1U2", "url": "https://www.uniprot.org/uniprotkb/Q9W1U2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 351, "end_pos": 353, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 351, "end_pos": 353 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"yes" } }, { "uniprot_canonical_ac": "Q9W1V2-1", "uniprot_ac": "Q9W1V2", "uniprot_id": "Q9W1V2_DROME", "mass": { "chemical_mass": 50696.0, "monoisotopic_mass": 50696.0 }, "refseq": { "ac": "NP_001261149", "name": "uncharacterized protein, isoform B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261149" }, "gene_names": [ { "name": "Dmel\\CG3085", "type": "recommended", "evidence": [ { "id": "Q9W1V2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W1V2" } ] }, { "name": "CG3085", "type": "synonym", "evidence": [ { "id": "NP_001261149", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261149" }, { "id": "Q9W1V2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W1V2" } ] }, { "name": "Dmel\\CG3085", "type": "synonym", "evidence": [ { "id": "NP_001261149", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261149" } ] }, { "name": "Dmel_CG3085", "type": "synonym", "evidence": [ { "id": "Q9W1V2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W1V2" } ] }, { "name": "anon-WO0140519.123", "type": "synonym", "evidence": [ { "id": "NP_001261149", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261149" }, { "id": "Q9W1V2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W1V2" } ] } ], "protein_names": [ { "name": "Tektin", "type": "recommended", "evidence": [ { "id": "Q9W1V2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W1V2/entry#names_and_taxonomy" } ] }, { "name": "CG3085-PB", "type": "synonym", "evidence": [ { "id": "NP_001261149", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261149" } ] }, { "name": "uncharacterized protein, isoform B", "type": "synonym", "evidence": [ { "id": "NP_001261149", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261149" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W1V2", "url": "https://www.uniprot.org/uniprotkb/Q9W1V2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG3085", "url": "https://www.uniprot.org/uniprotkb/Q9W1V2", "locus": { "chromosome": "2R", "start_pos": 23076857, "end_pos": 23074823, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0034816", "url": "https://www.ensemblgenomes.org/id/FBgn0034816" } ] } } ], "crossref": [ { "id": "FB:FBgn0034816", "url": "https://alliancegenome.org/gene/FB:FBgn0034816", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0034816", "url": "https://bgee.org/?page=gene&gene_id=FBgn0034816", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0034816", "url": "https://flybase.org/reports/FBgn0034816", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "37663", "url": "https://www.ncbi.nlm.nih.gov/gene/37663", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000435", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000435", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048256", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048256", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG3085", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3085", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FDHRGKM", "url": "https://omabrowser.org/oma/group/FDHRGKM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W1V2", "url": "https://www.orthodb.org/?gene=Q9W1V2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19960", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19960", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19960:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19960:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03148", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03148", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001261149", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261149", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W1V2", "url": "https://www.uniprot.org/uniprotkb/Q9W1V2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W1V2-1", "url": "https://www.uniprot.org/uniprotkb/Q9W1V2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFRSVVTMEKPLQHISLTDWYARVNQMRNVADARRSDAFAIRHSSRSLRNETRIEGDWANYETNEALTDRISELNRWRDIISKSFEKIEREIFMLQEEKNATERELEALAGPISVIAECLTIRDGRLGSEITYDEADTEIKNELVVLENNQRLLADRCQKAWEKLNRLEEVRFKIGLEIEFKVEAVQLDNSQLALDRNSANISYKPDPTRNPKNSCSYESWLENVKNIKLLAENELADTYAIREALFVCREKARNMLQSQQERAEHTIRKRIFETQRARNELEWQQLKMKEEMEKAMCEIRTSENALRDKTDALKLAETRLENRAQRSGMELCMDQAHDMLCLEVEKLREIRRRLQVKIDESKTNFSLLEEHGKRIDVDLENKQHSLMTDIRALDLRMRLRGGEFGSKVANASQTDRNITLTRMENEIPKD", "length": 432, "header": "tr|Q9W1V2-1|Q9W1V2_DROME Isoform 1 of Tektin OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG3085 PE=3 SV=1 CANONICAL=Q9W1V2-1" }, "isoforms": [ { "isoform_ac": "Q9W1V2-1", "url": "https://www.uniprot.org/uniprotkb/Q9W1V2/entry#Q9W1V2-1", "sequence": { "sequence": "MAFRSVVTMEKPLQHISLTDWYARVNQMRNVADARRSDAFAIRHSSRSLRNETRIEGDWANYETNEALTDRISELNRWRDIISKSFEKIEREIFMLQEEKNATERELEALAGPISVIAECLTIRDGRLGSEITYDEADTEIKNELVVLENNQRLLADRCQKAWEKLNRLEEVRFKIGLEIEFKVEAVQLDNSQLALDRNSANISYKPDPTRNPKNSCSYESWLENVKNIKLLAENELADTYAIREALFVCREKARNMLQSQQERAEHTIRKRIFETQRARNELEWQQLKMKEEMEKAMCEIRTSENALRDKTDALKLAETRLENRAQRSGMELCMDQAHDMLCLEVEKLREIRRRLQVKIDESKTNFSLLEEHGKRIDVDLENKQHSLMTDIRALDLRMRLRGGEFGSKVANASQTDRNITLTRMENEIPKD", "length": 432, "header": "tr|Q9W1V2-1|Q9W1V2_DROME Isoform 1 of Tektin OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG3085 PE=3 SV=1 CANONICAL=Q9W1V2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W1V2", "url": "https://www.uniprot.org/uniprotkb/Q9W1V2" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W1V2", "url": "https://www.uniprot.org/uniprotkb/Q9W1V2" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1V2", "url": "https://www.uniprot.org/uniprotkb/Q9W1V2" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1V2", "url": "https://www.uniprot.org/uniprotkb/Q9W1V2" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W1V2", "url": "https://www.uniprot.org/uniprotkb/Q9W1V2" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W1V2", "url": "https://www.uniprot.org/uniprotkb/Q9W1V2" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W1V2", "url": "https://www.uniprot.org/uniprotkb/Q9W1V2" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1V2", "url": "https://www.uniprot.org/uniprotkb/Q9W1V2" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1V2", "url": "https://www.uniprot.org/uniprotkb/Q9W1V2" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W1V2", "url": "https://www.uniprot.org/uniprotkb/Q9W1V2" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W1V2", "url": "https://www.uniprot.org/uniprotkb/Q9W1V2" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], 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Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1Y4", "url": "https://www.uniprot.org/uniprotkb/Q9W1Y4" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1Y4", "url": "https://www.uniprot.org/uniprotkb/Q9W1Y4" } ], "reference": [ { "type": "PubMed", 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Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W1Y4", "url": "https://www.uniprot.org/uniprotkb/Q9W1Y4" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W1Y4", "url": "https://www.uniprot.org/uniprotkb/Q9W1Y4" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1Y4", "url": "https://www.uniprot.org/uniprotkb/Q9W1Y4" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1Y4", "url": "https://www.uniprot.org/uniprotkb/Q9W1Y4" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"MTAEINKGPLLGMRHVQTLLLFFNITCLYIGRLNVGVAVVAMTNAESTNPDFPEYDWTLTQKSYILSSFFWGYIITQFLGGYLCKRYGVKSVMLWGSFASGIFSALTPLFIGFGEWQAYCGIRVLMGFAQGLIFPCIHQHLARWSPPAERNRLGALSHTGIECGNVCAMFFSGMIAKSAIGWPGISYVSAGLALAWCAFWFVFAADNAEESRYITQEELHYIESSLKHNEDYHKTVIPVPWMAIWTSAPFFALMVARCCETWGLSTLQAQIPTYMNGVLDMDMKSNAFFSALPFLAMWIMSYVYLIIADVLLAGNRLSLTALRKIFNSLAFWIPCATLIGIGFLDQEQKNLAIALMTISVGVNSGATIGSSLNTIDLSPNHASILMGIVNTAANVVPIVTPLAVGLIVHEDKNREEWQIVFIIAAVIFFIGNCVFLYYGTAVSQPWDAEDYLTEKVPDLAIAPAIHEAGKGIDGPSQKSMILKFH", "length": 485, "header": "tr|Q9W1Z3-1|Q9W1Z3_DROME Isoform 1 of Putative inorganic phosphate cotransporter OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG30265 PE=3 SV=2 CANONICAL=Q9W1Z3-1" }, "isoforms": [ { "isoform_ac": "Q9W1Z3-1", "url": "https://www.uniprot.org/uniprotkb/Q9W1Z3/entry#Q9W1Z3-1", "sequence": { "sequence": 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RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, 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"id": "Q9W1Z3", "url": "https://www.uniprot.org/uniprotkb/Q9W1Z3" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W1Z3", "url": "https://www.uniprot.org/uniprotkb/Q9W1Z3" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1Z3", "url": "https://www.uniprot.org/uniprotkb/Q9W1Z3" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { 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Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W1Z3", "url": "https://www.uniprot.org/uniprotkb/Q9W1Z3" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W1Z3", "url": "https://www.uniprot.org/uniprotkb/Q9W1Z3" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1Z3", "url": "https://www.uniprot.org/uniprotkb/Q9W1Z3" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W1Z3", "url": "https://www.uniprot.org/uniprotkb/Q9W1Z3" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W215", "url": "https://www.uniprot.org/uniprotkb/Q9W215" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W215", "url": "https://www.uniprot.org/uniprotkb/Q9W215" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W215", "url": "https://www.uniprot.org/uniprotkb/Q9W215" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W215", "url": "https://www.uniprot.org/uniprotkb/Q9W215" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W215", "url": "https://www.uniprot.org/uniprotkb/Q9W215" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W215", "url": "https://www.uniprot.org/uniprotkb/Q9W215" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W215", "url": "https://www.uniprot.org/uniprotkb/Q9W215" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W215", "url": "https://www.uniprot.org/uniprotkb/Q9W215" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W215", "url": "https://www.uniprot.org/uniprotkb/Q9W215" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG12190", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG12190", "resource": "KEGG Pathway" }, { "id": "R-DME-8953750", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8953750", "resource": "Reactome", "description": "Transcriptional Regulation by E2F6" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0M3Z6-1", "protein_name": "RING1 and YY1 binding protein", "gene_name": "LOC120102351", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTRGARPRPSSVTRRRRRWRGLVSSGDWRRRQRRRRRRRRLELEPSGGGRAGGAGGRGPLRDAADRASPLSGGARSCGAPGASPSMTMGDKKSPTRPKRQAKPAADEGFWDCSVCTFRNSAEAFKCSICDVRKGTSTRKPRINSQLVAQQVAQQYATPPPPKKEKKEKVEKPDKEKPEKDKDISPSVTKKNTNKKTKPKSDILKDPPSEANSIQSANATTKTSETNHTSRPRLKNVDRSTAQQLAVTVGNVTVIITDFKEKTRSSSTSSSTVTSSAGSEQQNQSSSGSESTDKGSSRSSTPKGDMSAVNDESF", "length": 313 }, "evidence": [ { "id": "RGD:1307077", "url": "https://alliancegenome.org/gene/RGD:1307077#orthology", "database": "AGR" }, 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"YY1-associated factor 2 isoform X1", "gene_name": "yaf2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADWLFYQPKVPKRQAKPSSDDGYWDCSVCTFKNTAEAFKCMMCDVRKGTSTRKPRPVSQLVSQQVTQQFASATLPKKEKKEKTEKDKNEREPTLKKNNHKKMRPRLKNVDRSSAQHLEVTVGDLTVIITDYKEKTKPSSSSSSSATSADHHSQSGSNSDNTEKGISRSSSPRGEVSSLNGESH", "length": 184 }, "evidence": [ { "id": "HGNC:17363", "url": "https://alliancegenome.org/gene/HGNC:17363#orthology", "database": "AGR" }, { "id": "MGI:1914307", "url": "https://alliancegenome.org/gene/MGI:1914307#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q7SYB3-1", "protein_name": "RING1 and YY1-binding protein A", "gene_name": "rybpa", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGDKKSPSRPKRQAKPSADNGFWDCSVCTFKNSAEAFKCSICDVRKGTSTRKPRINSQLVAQQVAQQYAAPPPAKKERRERTDRDLPDDDHFDMDNSDSDRLSSLHPDSDHPERLGLEGGQLDRGHSLKERRQERVLDKPQALDTDRRPERAGLTPDLLQQQQPQPQQHPQQPQQPQQHSQQQPQQHPPQQHNRIDREHTDRAMLEKLQPLREHMEKDHPHTAGSGMQPAERMGAEREELKKGKIERAMMEKHKERHKSLTPSKKPTPKKMKPKLIQKSPAGESNGMKPGKSVTKNNKSVISRPKLKNVDRSSAQQLAITVGNVTVIITDFKEKTRSSSTSSSTVTSSAGSEQQHLSSSSESTDKGSSRASTPRRDHSSGHNETL", "length": 385 }, "evidence": [ { "id": "RGD:1307077", "url": "https://alliancegenome.org/gene/RGD:1307077#orthology", "database": "AGR" }, { "id": "HGNC:10480", "url": "https://alliancegenome.org/gene/HGNC:10480#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030424-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030424-3#orthology", "database": "AGR" }, { "id": "MGI:1929059", "url": "https://alliancegenome.org/gene/MGI:1929059#orthology", "database": "AGR" }, { "id": "FB:FBgn0034763", "url": "https://alliancegenome.org/gene/FB:FBgn0034763#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8CCI5-1", "protein_name": "RING1 and YY1-binding protein", "gene_name": "Rybp", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTMGDKKSPTRPKRQAKPAADEGFWDCSVCTFRNSAEAFKCSICDVRKGTSTRKPRINSQLVAQQVAQQYATPPPPKKEKKEKVEKPDKEKPEKDKDISPSVTKKNTNKKTKPKSDILKDPPSEANSIQSANATTKTSETNHTSRPRLKNVDRSTAQQLAVTVGNVTVIITDFKEKTRSSSTSSSTVTSSAGSEQQNQSSSGSESTDKGSSRSSTPKGDMSAVNDESF", "length": 228 }, "evidence": [ { "id": "RGD:1307077", "url": "https://alliancegenome.org/gene/RGD:1307077#orthology", "database": "AGR" }, { "id": "HGNC:10480", "url": "https://alliancegenome.org/gene/HGNC:10480#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061103-96", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061103-96#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030424-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030424-3#orthology", "database": "AGR" }, { "id": "MGI:1929059", "url": "https://alliancegenome.org/gene/MGI:1929059#orthology", "database": "AGR" }, { "id": "FB:FBgn0034763", "url": "https://alliancegenome.org/gene/FB:FBgn0034763#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IY57-1", "protein_name": "YY1-associated factor 2", "gene_name": "YAF2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDKKSPTRPKRQPKPSSDEGYWDCSVCTFRNSAEAFKCMMCDVRKGTSTRKPRPVSQLVAQQVTQQFVPPTQSKKEKKDKVEKEKSEKETTSKKNSHKKTRPRLKNVDRSSAQHLEVTVGDLTVIITDFKEKTKSPPASSAASADQHSQSGSSSDNTERGMSRSSSPRGEASSLNGESH", "length": 180 }, "evidence": [ { "id": "HGNC:17363", "url": "https://alliancegenome.org/gene/HGNC:17363#orthology", "database": "AGR" }, { "id": "MGI:1914307", "url": "https://alliancegenome.org/gene/MGI:1914307#orthology", "database": "AGR" }, { "id": "RGD:1582851", "url": "https://alliancegenome.org/gene/RGD:1582851#orthology", "database": "AGR" }, { "id": "FB:FBgn0034763", "url": "https://alliancegenome.org/gene/FB:FBgn0034763#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8N488-1", "protein_name": "RING1 and YY1-binding protein", "gene_name": "RYBP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTMGDKKSPTRPKRQAKPAADEGFWDCSVCTFRNSAEAFKCSICDVRKGTSTRKPRINSQLVAQQVAQQYATPPPPKKEKKEKVEKQDKEKPEKDKEISPSVTKKNTNKKTKPKSDILKDPPSEANSIQSANATTKTSETNHTSRPRLKNVDRSTAQQLAVTVGNVTVIITDFKEKTRSSSTSSSTVTSSAGSEQQNQSSSGSESTDKGSSRSSTPKGDMSAVNDESF", "length": 228 }, "evidence": [ { "id": "RGD:1307077", "url": "https://alliancegenome.org/gene/RGD:1307077#orthology", "database": "AGR" }, { "id": "HGNC:10480", "url": "https://alliancegenome.org/gene/HGNC:10480#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061103-96", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061103-96#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030424-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030424-3#orthology", "database": "AGR" }, { "id": "MGI:1929059", "url": "https://alliancegenome.org/gene/MGI:1929059#orthology", "database": "AGR" }, { "id": "FB:FBgn0034763", "url": "https://alliancegenome.org/gene/FB:FBgn0034763#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99LW6-1", "protein_name": "YY1-associated factor 2", "gene_name": "Yaf2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGDKKSPTRPKRQPKPASDEGYWDCSVCTFRNSAEAFKCMMCDVRKGTSTRKPRPVSQLVAQQVTQQFVPPTQSKKEKKDRVEKDKSEKEAASKKNCHKKTRPRLKNVDRSSAQHLEVTVGDLTVIITDFKEKAKSAPASSAAGDQHSQGSCSSDSTERGVSRSSSPRGEASSLNGESH", "length": 179 }, "evidence": [ { "id": "HGNC:17363", "url": "https://alliancegenome.org/gene/HGNC:17363#orthology", "database": "AGR" }, { "id": "MGI:1914307", "url": "https://alliancegenome.org/gene/MGI:1914307#orthology", "database": "AGR" }, { "id": "RGD:1582851", "url": 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"https://www.uniprot.org/uniprotkb/Q9W215" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9W215", "url": "https://www.uniprot.org/uniprotkb/Q9W215" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "Q9W215", "url": "https://www.uniprot.org/uniprotkb/Q9W215" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q9W215", "url": "https://www.uniprot.org/uniprotkb/Q9W215" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": 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Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W222", "url": "https://www.uniprot.org/uniprotkb/Q9W222" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W222", 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Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W222", "url": "https://www.uniprot.org/uniprotkb/Q9W222" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W222", "url": "https://www.uniprot.org/uniprotkb/Q9W222" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi 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Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W225", "url": "https://www.uniprot.org/uniprotkb/Q9W225" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W225", "url": "https://www.uniprot.org/uniprotkb/Q9W225" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi 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UDP-glycosyltransferase family 317 member A1, isoform A OS=Drosophila melanogaster OX=7227 GN=Ugt317A1 PE=1 SV=3 CANONICAL=Q9W228-1" }, "isoforms": [ { "isoform_ac": "Q9W228-1", "url": "https://www.uniprot.org/uniprotkb/Q9W228/entry#Q9W228-1", "sequence": { "sequence": "MESQWNRWILLAILGLALGQISQAAKILVLFPHVNEGHFAVMRTLVTELANREHTIEVYTGHGLGESLDNVTETVTAEFPFWSELQKQAAPKGNLADLGLLPIEKLRQSLASVGARALDHFLAQEPIQKLLKMSYLEFDFDVILVDYFYTEALLALGALHQRPVVGIISTDFGNYMDAVQEALVPAACSPIDFERDQPEMSFSVRLGNIRTCIARRKQFIKDHYGGQEQLVTKYFQLQSSIPELQASQLSVLLLNSHVPLITPKVSIQQIIPAGGLHIRGPKELPWNVKRFLEEARPGAIYVQLGNEQACGQLPKEKLDTLFAFFSARKQSIIWTCHDVKTLEGLPKNVMIQHAVPQIDILAHPRVKAFLTNGDLLNLQEGIMRNVPILGLPLFQHEARNMELAVRLGVGLQLEEGNVTTESLNWAVDRLLLESHFQLTIRDVSLEFRDRPLGALASALFWVNYVARHKGGSALRTRGIGISSCQLHLFDLFVFYAGIATLVVSLLVALSFGGFYIWNKKNNSKSTKVN", "length": 529, "header": "tr|Q9W228-1|Q9W228_DROME Isoform 1 of UDP-glycosyltransferase family 317 member A1, isoform A OS=Drosophila melanogaster OX=7227 GN=Ugt317A1 PE=1 SV=3 CANONICAL=Q9W228-1" 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Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W228", "url": "https://www.uniprot.org/uniprotkb/Q9W228" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W228", "url": "https://www.uniprot.org/uniprotkb/Q9W228" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W228", "url": "https://www.uniprot.org/uniprotkb/Q9W228" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W228", "url": "https://www.uniprot.org/uniprotkb/Q9W228" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W228", "url": 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Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W228", "url": "https://www.uniprot.org/uniprotkb/Q9W228" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W228", "url": "https://www.uniprot.org/uniprotkb/Q9W228" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W228", "url": "https://www.uniprot.org/uniprotkb/Q9W228" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W228", "url": "https://www.uniprot.org/uniprotkb/Q9W228" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"Q9W230", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W230" } ] }, { "name": "CG3732", "type": "synonym", "evidence": [ { "id": "NP_611692", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611692" }, { "id": "Q9W230", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W230" } ] }, { "name": "Dmel\\CG3732", "type": "synonym", "evidence": [ { "id": "NP_611692", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611692" } ] }, { "name": "Dmel_CG3732", "type": "synonym", "evidence": [ { "id": "Q9W230", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W230" } ] } ], "protein_names": [ { "name": "Zinc finger Ran-binding domain-containing protein 2", "type": "recommended", "evidence": [ { "id": "Q9W230", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W230/entry#names_and_taxonomy" } ] }, { "name": "CG3732-PA", "type": "synonym", "evidence": [ { "id": "NP_611692", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611692" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_611692", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611692" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W230", "url": "https://www.uniprot.org/uniprotkb/Q9W230" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG3732", "url": "https://www.uniprot.org/uniprotkb/Q9W230", "locus": { "chromosome": "2R", "start_pos": 22638807, "end_pos": 22640201, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0034750", "url": "https://www.ensemblgenomes.org/id/FBgn0034750" } ] } } ], "crossref": [ { "id": "FB:FBgn0034750", "url": "https://alliancegenome.org/gene/FB:FBgn0034750", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0034750", "url": "https://bgee.org/?page=gene&gene_id=FBgn0034750", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0034750", "url": "https://flybase.org/reports/FBgn0034750", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "37588", "url": "https://www.ncbi.nlm.nih.gov/gene/37588", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001876", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001876", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036443", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036443", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG3732", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3732", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DSQCANV", "url": "https://omabrowser.org/oma/group/DSQCANV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W230", "url": "https://www.orthodb.org/?gene=Q9W230", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12999", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12999", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12999:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12999:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00641", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00641", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_611692", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611692", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W230", "url": "https://www.uniprot.org/uniprotkb/Q9W230", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W230-1", "url": "https://www.uniprot.org/uniprotkb/Q9W230-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSSNGGVASGAAGSSGVASPGDWICPDYDCRHLNFARRLQCNKCDRDRDGSDKPERDRDRDRERERGNGSSSSSSSSSKKKLGTEIGKAAADKSRGLFSAEDWQCSKCANVNWARRQTCNMCNAPKFSDVEERTGFGGGYNDRGVVEYKDRQDSDSEYDEFGRRKKRKHGEHREDSKRPRRSSRDEQRNDEEEDEDDDEGDDEDLSKYDLWGDEEVTSTDVKSKEGTGNGDKERKRTSRDSTSSVSSSSSSSSSSSSDSSSSSSSSSSSGGRRKTSSSGRR", "length": 282, "header": "tr|Q9W230-1|Q9W230_DROME Isoform 1 of Zinc finger Ran-binding domain-containing protein 2 OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG3732 PE=3 SV=1 CANONICAL=Q9W230-1" }, "isoforms": [ { "isoform_ac": "Q9W230-1", "url": "https://www.uniprot.org/uniprotkb/Q9W230/entry#Q9W230-1", "sequence": { "sequence": "MSSSNGGVASGAAGSSGVASPGDWICPDYDCRHLNFARRLQCNKCDRDRDGSDKPERDRDRDRERERGNGSSSSSSSSSKKKLGTEIGKAAADKSRGLFSAEDWQCSKCANVNWARRQTCNMCNAPKFSDVEERTGFGGGYNDRGVVEYKDRQDSDSEYDEFGRRKKRKHGEHREDSKRPRRSSRDEQRNDEEEDEDDDEGDDEDLSKYDLWGDEEVTSTDVKSKEGTGNGDKERKRTSRDSTSSVSSSSSSSSSSSSDSSSSSSSSSSSGGRRKTSSSGRR", "length": 282, "header": "tr|Q9W230-1|Q9W230_DROME Isoform 1 of Zinc finger Ran-binding domain-containing protein 2 OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG3732 PE=3 SV=1 CANONICAL=Q9W230-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W230", "url": "https://www.uniprot.org/uniprotkb/Q9W230" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W230", "url": "https://www.uniprot.org/uniprotkb/Q9W230" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W230", "url": "https://www.uniprot.org/uniprotkb/Q9W230" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W230", "url": "https://www.uniprot.org/uniprotkb/Q9W230" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W230", "url": "https://www.uniprot.org/uniprotkb/Q9W230" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W230", "url": "https://www.uniprot.org/uniprotkb/Q9W230" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W230", "url": "https://www.uniprot.org/uniprotkb/Q9W230" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W230", "url": "https://www.uniprot.org/uniprotkb/Q9W230" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W230", "url": "https://www.uniprot.org/uniprotkb/Q9W230" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W230", "url": "https://www.uniprot.org/uniprotkb/Q9W230" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W230", "url": "https://www.uniprot.org/uniprotkb/Q9W230" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], 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"name": "alkaline phosphatase 8, isoform B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001286709" }, "gene_names": [ { "name": "Alp8", "type": "recommended", "evidence": [ { "id": "Q9W273", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W273" } ] }, { "name": "Alp8", "type": "synonym", "evidence": [ { "id": "NP_001286709", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001286709" } ] }, { "name": "CG3264", "type": "synonym", "evidence": [ { "id": "NP_001286709", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001286709" }, { "id": "Q9W273", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W273" } ] }, { "name": "Dmel\\CG3264", "type": "synonym", "evidence": [ { "id": "NP_001286709", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001286709" }, { "id": "Q9W273", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W273" } ] }, { "name": 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"evidence": [ { "id": "0050589", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050589" } ] }, { "disease_id": "DOID:0110913", "recommended_name": { "id": "DOID:0110913", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110913", "name": "adult hypophosphatasia", "description": "A hypophosphatasia that has_material_basis_in a heterozygous or compound heterozygous mutation of the ALPL gene on chromosome 1p36.12." }, "synonyms": [ { "id": "DOID:0110913", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110913", "name": "mild hypophosphatasia", "description": "" }, { "id": "MONDO:1010154", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:1010154", "name": "adult hypophosphatasia", "description": "Adult hypophosphatasia (A-HPP) is a mildform of hypophosphatasia characterized by osteomalacia, chondrocalcinosis, osteoarthropathy, stress fractures duringmiddle age, and dental 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alkaline phosphatase (ALPL) on chromosome 1p36." }, "synonyms": [ { "id": "DOID:0110914", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110914", "name": "phosphoethanolaminuria", "description": "" }, { "id": "DOID:0110914", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110914", "name": "HOPS", "description": "" }, { "id": "DOID:0110914", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110914", "name": "HPPI", "description": "" }, { "id": "MONDO:1010169", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:1010169", "name": "infantile hypophosphatasia", "description": "Infantile hypophosphatasia (I-HPP) is a very rare, severe form of hypophosphatasia characterized by infantile rickets without elevated serum alkaline phosphatase (ALP) activity and a wide range of clinical manifestations due to hypomineralization." }, { "id": "MONDO:1010169", "resource": "MONDO", "url": 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mildform of hypophosphatasia characterized by onset after six months of age and widely variable clinical features from low bone mineral density for age, to unexplained fractures,skeletal deformities,and rickets with short stature and waddling gait." }, { "id": "MONDO:1010168", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:1010168", "name": "childhood hypophosphatasia", "description": "" }, { "id": "MONDO:1010168", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:1010168", "name": "hypophosphatasia of childhood", "description": "" }, { "id": "MONDO:1010168", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:1010168", "name": "pediatric hypophosphatasia", "description": "" }, { "id": "MONDO:1010168", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:1010168", "name": "childhood-onset hypophosphatasia", "description": "" }, { "id": "MIM:241510", "resource": "MIM", "url": "https://www.omim.org/entry/241510", "name": "Hypophosphatasia, childhood", "description": "Hypophosphatasia, childhood" } ], "unlinked_id_list": [], "evidence": [ { "id": "0110915", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110915" } ] }, { "disease_id": "DOID:13809", "recommended_name": { "id": "DOID:13809", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13809", "name": "familial combined hyperlipidemia", "description": "" }, "synonyms": [ { "id": "DOID:13809", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13809", "name": "familial multiple lipoprotein-type hyperlipidemia", "description": "" }, { "id": "DOID:13809", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13809", "name": "mixed hyperlipidaemia", "description": "" }, { "id": "DOID:13809", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13809", "name": "type IIb hyperlipoproteinemia", "description": "" }, { "id": "DOID:13809", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13809", "name": "hyperbetalipoproteinemia with prebetalipoproteinemia", "description": "" }, { "id": "MONDO:0007759", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007759", "name": "hyperlipidemia, familial combined, LPL related", "description": "" }, { "id": "MONDO:0007759", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007759", "name": "combined hyperlipidemia, familial", "description": "" }, { "id": "MONDO:0007759", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007759", "name": "FCHL", "description": "" }, { "id": "MONDO:0007759", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007759", "name": "hyperlipidemia, familial combined", "description": "" }, { "id": "MIM:144250", "resource": "MIM", "url": "https://www.omim.org/entry/144250", "name": "Hyperlipidemia, familial combined, 3", "description": "Hyperlipidemia, familial combined, 3" } ], "unlinked_id_list": [], "evidence": [ { "id": "13809", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13809" } ] }, { "disease_id": "DOID:14213", "recommended_name": { "id": "DOID:14213", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14213", "name": "hypophosphatasia", "description": "A syndrome characterized by disruption of mineralization of bones and teeth that has_material_basis_in mutation in the ALPL gene on chromosome 1p36.12." }, "synonyms": [ { "id": "DOID:14213", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14213", "name": "deficiency of alkaline phosphatase", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "14213", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14213" } ] }, { "disease_id": "DOID:2349", "recommended_name": { "id": "DOID:2349", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2349", "name": "arteriosclerosis", "description": "An artery disease that is characterized by a thickening and hardening of arterial walls in the arteries." }, "synonyms": [ { "id": "DOID:2349", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2349", "name": "Arteriosclerotic vascular disease", "description": "" } ], "unlinked_id_list": [ "DOID:2348" ], "evidence": [ { "id": "2349", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2349" } ] }, { "disease_id": "DOID:4676", "recommended_name": { "id": "DOID:4676", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4676", "name": "uremia", "description": "" }, "synonyms": [ { "id": "DOID:4676", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4676", "name": "UREMIA OF renal ORIGIN", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "4676", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4676" } ] }, { "disease_id": "DOID:8577", "recommended_name": { "id": "DOID:8577", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8577", "name": "ulcerative colitis", "description": "A colitis that is predominantly confined to the mucosa located_in colon and includes characteristic ulcers, or open sores." }, "synonyms": [ { "id": "DOID:8577", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8577", "name": "Left-sided ulcerative colitis", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "8577", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8577" } ] }, { "disease_id": "DOID:8719", "recommended_name": { "id": "DOID:8719", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8719", "name": "in situ carcinoma", "description": "A carcinoma that is an early development defined by the absence of invasion of surrounding tissues." }, "synonyms": [], "unlinked_id_list": [ "DOID:9108" ], "evidence": [ { "id": "8719", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8719" } ] }, { "disease_id": "DOID:8778", "recommended_name": { "id": "DOID:8778", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8778", "name": "Crohn's disease", "description": "An intestinal disease that involves inflammation located_in intestine." }, "synonyms": [ { "id": "DOID:8778", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8778", "name": "Crohn disease", "description": "" }, { "id": "DOID:8778", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8778", "name": "Crohn's disease of colon", "description": "" }, { "id": "DOID:8778", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8778", "name": "Crohn's disease of large bowel", "description": "" }, { "id": "DOID:8778", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8778", "name": "Granulomatous Colitis", "description": "" }, { "id": "DOID:8778", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8778", "name": "Pediatric Crohn's disease", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "8778", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8778" } ] }, { "disease_id": "DOID:9452", "recommended_name": { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "steatotic liver disease", "description": "A lipid storage disease characterized by the accumulation of large vacuoles of triglyceride fat in at least 5% of hepatocytes." }, "synonyms": [ { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "Fatty change of liver", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "Steatosis of liver", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "alcoholic fatty liver", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "hepatic lipidosis", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "SLD", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "fatty liver disease", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "hepatic steatosis", "description": "" }, { "id": "MONDO:0009220", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009220", "name": "visceral steatosis, congenital", "description": "" }, { "id": "MONDO:0009220", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009220", "name": "visceral steatosis, congenital", "description": "" }, { "id": "MONDO:0009220", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009220", "name": "fatal neonatal hepatic steatosis", "description": "" }, { "id": "MONDO:0009220", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009220", "name": "visceral steatosis", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "9452", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9452" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W273", "url": "https://www.uniprot.org/uniprotkb/Q9W273" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Alp8", "url": "https://www.uniprot.org/uniprotkb/Q9W273", "locus": { "chromosome": "2R", "start_pos": 22208464, "end_pos": 22210765, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0034712", "url": "https://www.ensemblgenomes.org/id/FBgn0034712" } ] } } ], "crossref": [ { "id": "FB:FBgn0034712", "url": "https://alliancegenome.org/gene/FB:FBgn0034712", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0034712", "url": "https://bgee.org/?page=gene&gene_id=FBgn0034712", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16012", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16012", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0034712", "url": "https://flybase.org/reports/FBgn0034712", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "37540", "url": "https://www.ncbi.nlm.nih.gov/gene/37540", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001952", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001952", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017850", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017850", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018299", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018299", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG3264", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3264", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NGYFAFI", "url": "https://omabrowser.org/oma/group/NGYFAFI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W273", "url": "https://www.orthodb.org/?gene=Q9W273", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11596", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11596", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11596:SF91", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11596:SF91", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00245", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00245", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-1483166", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1483166", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-6811438", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6811438", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-8935690", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8935690", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001286709", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001286709", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "15017", "url": "https://www.rhea-db.org/rhea/15017", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q9W273", "url": "https://www.uniprot.org/uniprotkb/Q9W273", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W273-1", "url": "https://www.uniprot.org/uniprotkb/Q9W273-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSSQRQLVLPILLLLALAGTALCGVQEVHNVLELTGQAANKLKFSTDVATEKYTPPEEMDPQYWYNIADEEITKRLQLPQPNSQKAKNIIMFLGDGMPLSTVAAARILKGQRQGNTGEESSLSFERFPYTGLSRTYCSNAQVPDSACTATAYLCGVKTNIVNIGVSAAVEYNNCTASQDPANRLTSIAEWAQNAGKSTGIVTTTTLTHASPSGAYAKTANRMWECDTDVTSYGVDANSCIDMATQLVTQTPGKNFEVMFGGGMGKFLPNSIVDSHGNPGERSDGVNLLSRWQGLHDGGVLVTNRNQLLKLNVSAVSSVIGLFQSKLMNFHLEADDTYQPTLSELTEVTIKKLSQNKEHGYFAFIEGGLIDYGNHYTKAGYALDEALEFEKAIQLARDMTDIEDTLIVVTADHGHAVSIAGYPGRGTPILGINQHDTDINGVQYSVLNYAAGPNQYLDENGQRIPLDDILGSDDAITPSYIPKDQGVHSGEDVGIFASGPQSHLFTGVMQQSTIPHLMAYAACIGSGKQVCDN", "length": 533, "header": "tr|Q9W273-1|Q9W273_DROME Isoform 1 of Alkaline phosphatase OS=Drosophila melanogaster OX=7227 GN=Alp8 PE=3 SV=1 CANONICAL=Q9W273-1" }, "isoforms": [ { "isoform_ac": "Q9W273-1", "url": "https://www.uniprot.org/uniprotkb/Q9W273/entry#Q9W273-1", "sequence": { "sequence": "MGSSQRQLVLPILLLLALAGTALCGVQEVHNVLELTGQAANKLKFSTDVATEKYTPPEEMDPQYWYNIADEEITKRLQLPQPNSQKAKNIIMFLGDGMPLSTVAAARILKGQRQGNTGEESSLSFERFPYTGLSRTYCSNAQVPDSACTATAYLCGVKTNIVNIGVSAAVEYNNCTASQDPANRLTSIAEWAQNAGKSTGIVTTTTLTHASPSGAYAKTANRMWECDTDVTSYGVDANSCIDMATQLVTQTPGKNFEVMFGGGMGKFLPNSIVDSHGNPGERSDGVNLLSRWQGLHDGGVLVTNRNQLLKLNVSAVSSVIGLFQSKLMNFHLEADDTYQPTLSELTEVTIKKLSQNKEHGYFAFIEGGLIDYGNHYTKAGYALDEALEFEKAIQLARDMTDIEDTLIVVTADHGHAVSIAGYPGRGTPILGINQHDTDINGVQYSVLNYAAGPNQYLDENGQRIPLDDILGSDDAITPSYIPKDQGVHSGEDVGIFASGPQSHLFTGVMQQSTIPHLMAYAACIGSGKQVCDN", "length": 533, "header": "tr|Q9W273-1|Q9W273_DROME Isoform 1 of Alkaline phosphatase OS=Drosophila melanogaster OX=7227 GN=Alp8 PE=3 SV=1 CANONICAL=Q9W273-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W273", "url": "https://www.uniprot.org/uniprotkb/Q9W273" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W273", "url": "https://www.uniprot.org/uniprotkb/Q9W273" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W273", "url": "https://www.uniprot.org/uniprotkb/Q9W273" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W273", "url": "https://www.uniprot.org/uniprotkb/Q9W273" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W273", "url": "https://www.uniprot.org/uniprotkb/Q9W273" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W273", "url": "https://www.uniprot.org/uniprotkb/Q9W273" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W273", "url": "https://www.uniprot.org/uniprotkb/Q9W273" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W273", "url": "https://www.uniprot.org/uniprotkb/Q9W273" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W273", "url": "https://www.uniprot.org/uniprotkb/Q9W273" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W273", "url": "https://www.uniprot.org/uniprotkb/Q9W273" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W273", "url": "https://www.uniprot.org/uniprotkb/Q9W273" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG3264", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3264", "resource": "KEGG Pathway" }, { "id": "R-DME-1483166", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1483166", "resource": "Reactome", "description": "Synthesis of PA" }, { "id": "R-DME-6811438", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6811438", "resource": "Reactome", "description": "Intra-Golgi traffic" }, { "id": "R-DME-8935690", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8935690", "resource": "Reactome", "description": "Digestion" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0L8R7-1", "protein_name": "Alkaline phosphatase", "gene_name": "Akp3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPTLQFQRGIEASKMTQQVKVPATQAESNTWSTHKVEEENPAFWNQKAADALNVAKKLQPIQTSAKNLIIFLGDGMGVPTVTATRILKGQLEGNLGPETPLAMDHFPYMALSKTYSVDRQVPDSASTATAYLCGVKTNYKTIGVSAAARFDQCNTTFGNEVLSVMYRAKKAGKSVGVVTTTRVQHASPAGTYVHTVNRNWYGDADMPASALQEGCKDIATQLVSNMDINVILGGGRKYMFPAGTPDPEYPNDVNETGTRLDGKNLVQEWLSKHQGSQYVWNRQELIQKSLDPSVTYLMGLFEPVDTKFEIQRDPLMDPSLKDMTEAALHVLSRNPKGFYLFVEGGRIDRGHHLGTAYLALTEAVMFDSAIERASQLTSEQDTLTIVTADHSHVFSFGGYTLRGTSIFGLAPLNALDGKPYTSILYGNGPGYVGTGERPNVTDAESHDPSYQQQAAVPVKSETHGGEDVAIFARGPQAHLLHGVQEQNYIAHVMAFAGCLEPYTDCGLAPPADENRPTTPVQNSTTTTTTTTTTTTTRVQNSASSLGPATGPLALALLAKALMLLLGAPADF", "length": 571 }, "evidence": [ { "id": "MGI:87984", "url": "https://alliancegenome.org/gene/MGI:87984#orthology", "database": "AGR" }, { "id": "HGNC:441", "url": "https://alliancegenome.org/gene/HGNC:441#orthology", "database": "AGR" }, { "id": "HGNC:437", "url": "https://alliancegenome.org/gene/HGNC:437#orthology", "database": "AGR" }, { "id": "FB:FBgn0034712", "url": "https://alliancegenome.org/gene/FB:FBgn0034712#orthology", "database": "AGR" }, { "id": "RGD:621650", "url": "https://alliancegenome.org/gene/RGD:621650#orthology", "database": "AGR" }, { "id": "SGD:S000002889", "url": "https://alliancegenome.org/gene/SGD:S000002889#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ADM6-1", "protein_name": "Alkaline phosphatase", "gene_name": "Alpp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAMWGACLLLLGLSLQMSLSLVPVEEENPAFWNRKAAEALEAAKKLQPIQTSANNLIILMGDGMGVSTVTATRILKGQQQGHLGPETPLAMDRFPHMALSKTYNTDKQVPDSAGTGTAFLCGVKTNMKVIGLSAAARFNQCNTTWGNEVVSVMHRAKKAGKSVGVVTTTSVQHASPAGTYAHTVNRNWYSDAHMSTAALQEGCKDIAMQLISNTDIDVILGGGRKFMFPKGTPDQEYPTDPQQAGTRLDGRNLVQEWLAKHQGAQYVWNRTELIQASLNRSVTHLMGLFEPNDMKYNIDRDPTQDPSLAEMTEVAVHMLSRNPKGFYLFVEGGRIDHGHHEAIAYRALTEAVMFDSAVDKADKLTSEKDTMIIVTADHSHVFSFGGYTQREASIFGLAPFKAGDGKSFTSILYGNGPGYKLNNGIRADVTEEESSNPTYQQQAAVPLSSETHSGEDVAIFARGPQAHLVHGVQEQNYIAHVMAFAGCLEPYTDCGLAPPAGRSSAVSPGYISTLLCLLAGTMLMLMVSAEP", "length": 531 }, "evidence": [ { "id": "MGI:108009", "url": "https://alliancegenome.org/gene/MGI:108009#orthology", "database": "AGR" }, { "id": "FB:FBgn0034712", "url": "https://alliancegenome.org/gene/FB:FBgn0034712#orthology", "database": "AGR" }, { "id": "RGD:2325055", "url": "https://alliancegenome.org/gene/RGD:2325055#orthology", "database": "AGR" }, { "id": "SGD:S000002889", "url": "https://alliancegenome.org/gene/SGD:S000002889#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M8U7-1", "protein_name": "Alkaline phosphatase", "gene_name": "Alpg", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQGAWVLLLLLLGLRLQLSFGVIPVEEENPAFWNQKAKEALDVAKKLKPIRTSAKNLIIFLGDGMGVPTVTATRILKGQLGGHLGPETPLAMDHFPFTALSKTYNVDRQVPDSAGTATAYLCGVKANYKTIGVSAAARFNQCNSTFGNEVFSVMHRAKKAGKSVGVVTTTSVQHASPAGTYAHTVNCDWYSDAHMATAALQEGCKDIAMQLISNMDIDVILGGGRKFMFPKGTPDPEYSGNRAQSGTRLDGQNLVQKWLAKHQGARYVWNRTELIQASQDSAVTHLMGLFEPNDMKYDIYRDPTQDPSLAEMTEVAVHLLSRNPKGFYLFVEGGHIDHGHHESIAYRALTEAVMFDSAVDKANKLTSEKDTMILVTADHSHVFSFGGYVPRGTSIFGLGASFNALDGRPFTSILYGNGPGYKLEKGTRPDVTDKESRDPKYRQQAAVPLSSETHSGEDVAIFARGPQAHLVHGVQEQNYIAHVMAFAGCLEPYTDCGLAPPAGRSSAVSPGYISTLLCLLAGTMLMLLVSAEP", "length": 533 }, "evidence": [ { "id": "HGNC:441", "url": "https://alliancegenome.org/gene/HGNC:441#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1Q5B5-1", "protein_name": "Alkaline phosphatase", "gene_name": "alpl", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWECGCFLVLWSELSVVWHPWNVKIRKRRLIDNKMKVVQLLILSCLVWEGKTKVQFPEQEKRPDYWRDFAQRSLKDALKLQELNKNIAKNIILFLGDGMGVPTVTAARILKGQLSGQNGEETQLEMDKFPHVALSKTYNTNAQVPDSAGTATAFLCGVKANEGTVGVSAAAVRSQCNTTQGNEVTSILKWAKDAGKSVGIVTTTRVNHATPSAAYAHCVDRDWYSDADMPNEALQSGCKDIARQLFENIPDINVIMGGGRRSMYPKNTPDVEYPGDKKQNGTRKDGRNLVGEWIDRVKEKRGFYVWNKKDLLSLNPNNVDYLLGLFEPADLNYELERNTENDPSLTEMVDVAIKILKKNERGFFLLVEGGRIDHGHHEGKAKQALHEAVEMDRAITRAGLLTSEYDTLTVVTADHSHVFSFGGYTPRGNSIFGLAPTLSDVDQKPFTAILYGNGPGFKLVNGARENVSTVDYQQNNYQAQSAVPLRMETHGGEDVAIFSKGPMAHLLHGVQEQHYIPHVMAYAACIGQNKDHCRTNSGSSSYFSHISPALLFPLLVKWLLC", "length": 561 }, "evidence": [ { "id": "MGI:87983", "url": "https://alliancegenome.org/gene/MGI:87983#orthology", "database": "AGR" }, { "id": "HGNC:438", "url": "https://alliancegenome.org/gene/HGNC:438#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F8VPQ6-1", "protein_name": "Alkaline phosphatase", "gene_name": "Alpi", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQGDWVLLLFLGLRIHLSFGIIPAEEENPAFWNKKAAEALDAAKKLQPIQTSAKNLIIFLGDGMGVPTVTATRILKGQLEGHLGPETPLAMDLFPYMALSKTYNVDRQVPDSAGTATAYLCGVKANYKTIGLSAAARLDQCNTTFGNEVFSVMYRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRNWYSDAEMPASALQDGCKDIATQLISNMDIDVILGGGRKFMFPKGTPDPEYPSDSNQSGTRLDDQNLVQTWLSKHQGARYVWNRSELIQASQDPAVTHLMGLFEPTEMKYDANRNPSVDPSLAEMTEVAVRMLSRNPQGFYLFVEGGRIDQGHHAGTAYLALTEAVMFDSAIEKASQLTNEKDTLILITADHSHVFAFGGYTLRGTSIFGLAPLKALDDKSYTSILYGNGPGYELKSGNRPNVTEAQSVDPNYKQQAAVPLSSETHGGEDVAIFARGPQAHLVHGVQEQNYIAHVMAFAGCLEPYTDCGLAPPAGQSPVITPGQATTTNNAAGQATTTNNAAGQATVLLSLQLLVSMLLLVGTAMVVS", "length": 554 }, "evidence": [ { "id": "RGD:2099", "url": "https://alliancegenome.org/gene/RGD:2099#orthology", "database": "AGR" }, { "id": "MGI:1924018", "url": "https://alliancegenome.org/gene/MGI:1924018#orthology", "database": "AGR" }, { "id": "HGNC:441", "url": "https://alliancegenome.org/gene/HGNC:441#orthology", "database": "AGR" }, { "id": "HGNC:437", "url": "https://alliancegenome.org/gene/HGNC:437#orthology", "database": "AGR" }, { "id": "FB:FBgn0034712", "url": "https://alliancegenome.org/gene/FB:FBgn0034712#orthology", "database": "AGR" }, { "id": "SGD:S000002889", "url": "https://alliancegenome.org/gene/SGD:S000002889#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M9PD70-1", "protein_name": "alkaline phosphatase", "gene_name": "Alp1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRALRFFAALALQLTACSSQYKYGPEQSWDLDSISELKSKEFWFHDAQRTLYNKLSTPPNQYRAKNVIFFLGDGMSVPTVTAGRIFDGQLRGVVGERNRLEFEKFNYVGLSKTYCVNKQVADSACTASAYLSGIKANYLTIGVTADVELNDCRGSRLPQNRLSSIAAWALKGSKSAGLVTTTRVTHASPAGVYAHTSNRDFESDYDVTKLGQNPGNCPDIAQQLIDGDVGKRLRVVMGGGTIKFLPNTTNDVFGNKGQRLDNRNLIEEWQQTKPGNARVVFSRTDLLNNDAQNTDFLLGLFNASHLAYHMDDSIDTPTLPEMTAAAINVLSRDPNGYFLFVEGGRIDHAHHETKAKKALDETVQFSDAVRKARQLTNPWDTLIVVSADHGHTVTISGYPDVNNSIVGLNSELSNVDQLPYTSISYANGPAYERFYKSTDGVVERVDLRNLDFSKPDAIYPHGVPMTEETHGGGDVAVYAHVVEYLLQGPWSHLFTGVYEQSTLPHLMGFASCLGPGITYCDLQPKARYSP", "length": 530 }, "evidence": [ { "id": "RGD:2099", "url": "https://alliancegenome.org/gene/RGD:2099#orthology", "database": "AGR" }, { "id": "MGI:1924018", "url": "https://alliancegenome.org/gene/MGI:1924018#orthology", "database": "AGR" }, { "id": "MGI:87984", "url": "https://alliancegenome.org/gene/MGI:87984#orthology", "database": "AGR" }, { "id": "MGI:108009", "url": "https://alliancegenome.org/gene/MGI:108009#orthology", "database": "AGR" }, { "id": "MGI:87983", "url": "https://alliancegenome.org/gene/MGI:87983#orthology", "database": "AGR" }, { "id": "HGNC:438", "url": "https://alliancegenome.org/gene/HGNC:438#orthology", "database": "AGR" }, { "id": "HGNC:441", "url": "https://alliancegenome.org/gene/HGNC:441#orthology", "database": "AGR" }, { "id": "HGNC:437", "url": "https://alliancegenome.org/gene/HGNC:437#orthology", "database": "AGR" }, { "id": "RGD:2325055", "url": "https://alliancegenome.org/gene/RGD:2325055#orthology", "database": "AGR" }, { "id": "RGD:621650", "url": "https://alliancegenome.org/gene/RGD:621650#orthology", "database": "AGR" }, { "id": "RGD:2100", "url": "https://alliancegenome.org/gene/RGD:2100#orthology", "database": "AGR" }, { "id": "SGD:S000002889", "url": "https://alliancegenome.org/gene/SGD:S000002889#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P05186-1", "protein_name": "Alkaline phosphatase, tissue-nonspecific isozyme", "gene_name": "ALPL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MISPFLVLAIGTCLTNSLVPEKEKDPKYWRDQAQETLKYALELQKLNTNVAKNVIMFLGDGMGVSTVTAARILKGQLHHNPGEETRLEMDKFPFVALSKTYNTNAQVPDSAGTATAYLCGVKANEGTVGVSAATERSRCNTTQGNEVTSILRWAKDAGKSVGIVTTTRVNHATPSAAYAHSADRDWYSDNEMPPEALSQGCKDIAYQLMHNIRDIDVIMGGGRKYMYPKNKTDVEYESDEKARGTRLDGLDLVDTWKSFKPRYKHSHFIWNRTELLTLDPHNVDYLLGLFEPGDMQYELNRNNVTDPSLSEMVVVAIQILRKNPKGFFLLVEGGRIDHGHHEGKAKQALHEAVEMDRAIGQAGSLTSSEDTLTVVTADHSHVFTFGGYTPRGNSIFGLAPMLSDTDKKPFTAILYGNGPGYKVVGGERENVSMVDYAHNNYQAQSAVPLRHETHGGEDVAVFSKGPMAHLLHGVHEQNYVPHVMAYAACIGANLGHCAPASSAGSLAAGPLLLALALYPLSVLF", "length": 524 }, "evidence": [ { "id": "MGI:87983", "url": "https://alliancegenome.org/gene/MGI:87983#orthology", "database": "AGR" }, { "id": "HGNC:438", "url": "https://alliancegenome.org/gene/HGNC:438#orthology", "database": "AGR" }, { "id": "FB:FBgn0034712", "url": "https://alliancegenome.org/gene/FB:FBgn0034712#orthology", "database": "AGR" }, { "id": "RGD:2100", "url": "https://alliancegenome.org/gene/RGD:2100#orthology", "database": "AGR" }, { "id": "SGD:S000002889", "url": "https://alliancegenome.org/gene/SGD:S000002889#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P05187-1", "protein_name": "Alkaline phosphatase, placental type", "gene_name": "ALPP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLGPCMLLLLLLLGLRLQLSLGIIPVEEENPDFWNREAAEALGAAKKLQPAQTAAKNLIIFLGDGMGVSTVTAARILKGQKKDKLGPEIPLAMDRFPYVALSKTYNVDKHVPDSGATATAYLCGVKGNFQTIGLSAAARFNQCNTTRGNEVISVMNRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRNWYSDADVPASARQEGCQDIATQLISNMDIDVILGGGRKYMFRMGTPDPEYPDDYSQGGTRLDGKNLVQEWLAKRQGARYVWNRTELMQASLDPSVTHLMGLFEPGDMKYEIHRDSTLDPSLMEMTEAALRLLSRNPRGFFLFVEGGRIDHGHHESRAYRALTETIMFDDAIERAGQLTSEEDTLSLVTADHSHVFSFGGYPLRGSSIFGLAPGKARDRKAYTVLLYGNGPGYVLKDGARPDVTESESGSPEYRQQSAVPLDEETHAGEDVAVFARGPQAHLVHGVQEQTFIAHVMAFAACLEPYTACDLAPPAGTTDAAHPGRSVVPALLPLLAGTLLLLETATAP", "length": 535 }, "evidence": [ { "id": "RGD:2099", "url": "https://alliancegenome.org/gene/RGD:2099#orthology", "database": "AGR" }, { "id": "MGI:1924018", "url": "https://alliancegenome.org/gene/MGI:1924018#orthology", "database": "AGR" }, { "id": "MGI:87984", "url": "https://alliancegenome.org/gene/MGI:87984#orthology", "database": "AGR" }, { "id": "MGI:108009", "url": "https://alliancegenome.org/gene/MGI:108009#orthology", "database": "AGR" }, { "id": "RGD:2325055", "url": "https://alliancegenome.org/gene/RGD:2325055#orthology", "database": "AGR" }, { "id": "RGD:621650", "url": "https://alliancegenome.org/gene/RGD:621650#orthology", "database": "AGR" }, { "id": "SGD:S000002889", "url": "https://alliancegenome.org/gene/SGD:S000002889#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P08289-1", "protein_name": "Alkaline phosphatase, tissue-nonspecific isozyme", "gene_name": "Alpl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MILPFLVLAIGTCLTNSFVPEKEKDPSYWRQQAQETLKNALKLQKLNTNVAKNIIMFLGDGMGVSTVTAARILKGQLHHNTGEETRLEMDKFPFVALSKTYNTNAQVPDSAGTATAYLCGVKANEGTVGVSAATERTRCNTTQGNEVTSILRWAKDAGKSVGIVTTTRVNHATPSAAYAHSADRDWYSDNEMPPEALSQGCKDIAYQLMHNIKDIDVIMGGGRKYMYPKNRTDVEYELDEKARGTRLDGLDLISIWKSFKPRHKHSHYVWNRTELLALDPSRVDYLLGLFEPGDMQYELNRNNLTDPSLSEMVEVALRILTKNPKGFFLLVEGGRIDHGHHEGKAKQALHEAVEMDEAIGKAGTMTSQKDTLTVVTADHSHVFTFGGYTPRGNSIFGLAPMVSDTDKKPFTAILYGNGPGYKVVDGERENVSMVDYAHNNYQAQSAVPLRHETHGGEDVAVFAKGPMAHLLHGVHEQNYIPHVMAYASCIGANLDHCAWASSASSPSPGALLLPLALFPLRTLF", "length": 524 }, "evidence": [ { "id": "MGI:87983", "url": "https://alliancegenome.org/gene/MGI:87983#orthology", "database": "AGR" }, { "id": "HGNC:438", "url": "https://alliancegenome.org/gene/HGNC:438#orthology", "database": "AGR" }, { "id": "FB:FBgn0034712", "url": "https://alliancegenome.org/gene/FB:FBgn0034712#orthology", "database": "AGR" }, { "id": "RGD:2100", "url": "https://alliancegenome.org/gene/RGD:2100#orthology", "database": "AGR" }, { "id": "SGD:S000002889", "url": "https://alliancegenome.org/gene/SGD:S000002889#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P09242-1", "protein_name": "Alkaline phosphatase, tissue-nonspecific isozyme", "gene_name": "Alpl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MISPFLVLAIGTCLTNSFVPEKERDPSYWRQQAQETLKNALKLQKLNTNVAKNVIMFLGDGMGVSTVTAARILKGQLHHNTGEETRLEMDKFPFVALSKTYNTNAQVPDSAGTATAYLCGVKANEGTVGVSAATERTRCNTTQGNEVTSILRWAKDAGKSVGIVTTTRVNHATPSAAYAHSADRDWYSDNEMPPEALSQGCKDIAYQLMHNIKDIDVIMGGGRKYMYPKNRTDVEYELDEKARGTRLDGLDLISIWKSFKPRHKHSHYVWNRTELLALDPSRVDYLLGLFEPGDMQYELNRNNLTDPSLSEMVEVALRILTKNLKGFFLLVEGGRIDHGHHEGKAKQALHEAVEMDQAIGKAGAMTSQKDTLTVVTADHSHVFTFGGYTPRGNSIFGLAPMVSDTDKKPFTAILYGNGPGYKVVDGERENVSMVDYAHNNYQAQSAVPLRHETHGGEDVAVFAKGPMAHLLHGVHEQNYIPHVMAYASCIGANLDHCAWAGSGSAPSPGALLLPLAVLSLRTLF", "length": 524 }, "evidence": [ { "id": "MGI:87983", "url": "https://alliancegenome.org/gene/MGI:87983#orthology", "database": "AGR" }, { "id": "HGNC:438", "url": "https://alliancegenome.org/gene/HGNC:438#orthology", "database": "AGR" }, { "id": "FB:FBgn0034712", "url": "https://alliancegenome.org/gene/FB:FBgn0034712#orthology", "database": "AGR" }, { "id": "RGD:2100", "url": "https://alliancegenome.org/gene/RGD:2100#orthology", "database": "AGR" }, { "id": "SGD:S000002889", "url": "https://alliancegenome.org/gene/SGD:S000002889#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P09923-1", "protein_name": "Intestinal-type alkaline phosphatase", "gene_name": "ALPI", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQGPWVLLLLGLRLQLSLGVIPAEEENPAFWNRQAAEALDAAKKLQPIQKVAKNLILFLGDGLGVPTVTATRILKGQKNGKLGPETPLAMDRFPYLALSKTYNVDRQVPDSAATATAYLCGVKANFQTIGLSAAARFNQCNTTRGNEVISVMNRAKQAGKSVGVVTTTRVQHASPAGTYAHTVNRNWYSDADMPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPADASQNGIRLDGKNLVQEWLAKHQGAWYVWNRTELMQASLDQSVTHLMGLFEPGDTKYEIHRDPTLDPSLMEMTEAALRLLSRNPRGFYLFVEGGRIDHGHHEGVAYQALTEAVMFDDAIERAGQLTSEEDTLTLVTADHSHVFSFGGYTLRGSSIFGLAPSKAQDSKAYTSILYGNGPGYVFNSGVRPDVNESESGSPDYQQQAAVPLSSETHGGEDVAVFARGPQAHLVHGVQEQSFVAHVMAFAACLEPYTACDLAPPACTTDAAHPVAASLPLLAGTLLLLGASAAP", "length": 528 }, "evidence": [ { "id": "RGD:2099", "url": "https://alliancegenome.org/gene/RGD:2099#orthology", "database": "AGR" }, { "id": "MGI:1924018", "url": "https://alliancegenome.org/gene/MGI:1924018#orthology", "database": "AGR" }, { "id": "MGI:87984", "url": "https://alliancegenome.org/gene/MGI:87984#orthology", "database": "AGR" }, { "id": "MGI:108009", "url": "https://alliancegenome.org/gene/MGI:108009#orthology", "database": "AGR" }, { "id": "HGNC:437", "url": "https://alliancegenome.org/gene/HGNC:437#orthology", "database": "AGR" }, { "id": "FB:FBgn0034712", "url": "https://alliancegenome.org/gene/FB:FBgn0034712#orthology", "database": "AGR" }, { "id": "RGD:621650", "url": "https://alliancegenome.org/gene/RGD:621650#orthology", "database": "AGR" }, { "id": "SGD:S000002889", "url": "https://alliancegenome.org/gene/SGD:S000002889#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P10696-1", "protein_name": "Alkaline phosphatase, germ cell type", "gene_name": "ALPG", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQGPWVLLLLGLRLQLSLGIIPVEEENPDFWNRQAAEALGAAKKLQPAQTAAKNLIIFLGDGMGVSTVTAARILKGQKKDKLGPETFLAMDRFPYVALSKTYSVDKHVPDSGATATAYLCGVKGNFQTIGLSAAARFNQCNTTRGNEVISVMNRAKKAGKSVGVVTTTRVQHASPAGAYAHTVNRNWYSDADVPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPDDYSQGGTRLDGKNLVQEWLAKHQGARYVWNRTELLQASLDPSVTHLMGLFEPGDMKYEIHRDSTLDPSLMEMTEAALLLLSRNPRGFFLFVEGGRIDHGHHESRAYRALTETIMFDDAIERAGQLTSEEDTLSLVTADHSHVFSFGGYPLRGSSIFGLAPGKARDRKAYTVLLYGNGPGYVLKDGARPDVTESESGSPEYRQQSAVPLDGETHAGEDVAVFARGPQAHLVHGVQEQTFIAHVMAFAACLEPYTACDLAPRAGTTDAAHPGPSVVPALLPLLAGTLLLLGTATAP", "length": 532 }, "evidence": [ { "id": "RGD:2099", "url": "https://alliancegenome.org/gene/RGD:2099#orthology", "database": "AGR" }, { "id": "MGI:1924018", "url": "https://alliancegenome.org/gene/MGI:1924018#orthology", "database": "AGR" }, { "id": "MGI:87984", "url": "https://alliancegenome.org/gene/MGI:87984#orthology", "database": "AGR" }, { "id": "MGI:108009", "url": "https://alliancegenome.org/gene/MGI:108009#orthology", "database": "AGR" }, { "id": "HGNC:441", "url": "https://alliancegenome.org/gene/HGNC:441#orthology", "database": "AGR" }, { "id": "FB:FBgn0034712", "url": "https://alliancegenome.org/gene/FB:FBgn0034712#orthology", "database": "AGR" }, { "id": "RGD:621650", "url": "https://alliancegenome.org/gene/RGD:621650#orthology", "database": "AGR" }, { "id": "SGD:S000002889", "url": "https://alliancegenome.org/gene/SGD:S000002889#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P11491-1", "protein_name": "Repressible alkaline phosphatase", "gene_name": "PHO8", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MMTHTLPSEQTRLVPGSDSSSRPKKRRISKRSKIIVSTVVCIGLLLVLVQLAFPSSFALRSASHKKKNVIFFVTDGMGPASLSMARSFNQHVNDLPIDDILTLDEHFIGSSRTRSSDSLVTDSAAGATAFACALKSYNGAIGVDPHHRPCGTVLEAAKLAGYLTGLVVTTRITDATPASFSSHVDYRWQEDLIATHQLGEYPLGRVVDLLMGGGRSHFYPQGEKASPYGHHGARKDGRDLIDEAQSNGWQYVGDRKNFDSLLKSHGENVTLPFLGLFADNDIPFEIDRDEKEYPSLKEQVKVALGALEKASNEDKDSNGFFLMVEGSRIDHAGHQNDPASQVREVLAFDEAFQYVLEFAENSDTETVLVSTSDHETGGLVTSRQVTASYPQYVWYPQVLANATHSGEFLKRKLVDFVHEHKGASSKIENFIKHEILEKDLGIYDYTDSDLETLIHLDDNANAIQDKLNDMVSFRAQIGWTTHGHSAVDVNIYAYANKKATWSYVLNNLQGNHENTEVGQFLENFLELNLNEVTDLIRDTKHTSDFDATEIASEVQHYDEYYHELTN", "length": 566 }, "evidence": [ { "id": "RGD:2099", "url": "https://alliancegenome.org/gene/RGD:2099#orthology", "database": "AGR" }, { "id": "MGI:1924018", "url": "https://alliancegenome.org/gene/MGI:1924018#orthology", "database": "AGR" }, { "id": "MGI:87984", "url": "https://alliancegenome.org/gene/MGI:87984#orthology", "database": "AGR" }, { "id": "MGI:108009", "url": "https://alliancegenome.org/gene/MGI:108009#orthology", "database": "AGR" }, { "id": "MGI:87983", "url": "https://alliancegenome.org/gene/MGI:87983#orthology", "database": "AGR" }, { "id": "HGNC:438", "url": "https://alliancegenome.org/gene/HGNC:438#orthology", "database": "AGR" }, { "id": "HGNC:441", "url": "https://alliancegenome.org/gene/HGNC:441#orthology", "database": "AGR" }, { "id": "HGNC:437", "url": "https://alliancegenome.org/gene/HGNC:437#orthology", "database": "AGR" }, { "id": "FB:FBgn0034712", "url": "https://alliancegenome.org/gene/FB:FBgn0034712#orthology", "database": "AGR" }, { "id": "RGD:2325055", "url": "https://alliancegenome.org/gene/RGD:2325055#orthology", "database": "AGR" }, { "id": "RGD:621650", "url": "https://alliancegenome.org/gene/RGD:621650#orthology", "database": "AGR" }, { "id": "RGD:2100", "url": "https://alliancegenome.org/gene/RGD:2100#orthology", "database": "AGR" }, { "id": "SGD:S000002889", "url": "https://alliancegenome.org/gene/SGD:S000002889#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P15693-1", "protein_name": "Intestinal-type alkaline phosphatase 1", "gene_name": "Alpi", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQGDWVLLLLLGLRIHLSFGVIPVEEENPVFWNQKAKEALDVAKKLQPIQTSAKNLILFLGDGMGVPTVTATRILKGQLGGHLGPETPLAMDHFPFTALSKTYNVDRQVPDSAGTATAYLCGVKANYKTIGVSAAARFNQCNSTFGNEVFSVMHRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRDWYSDADMPSSALQEGCKDIATQLISNMDIDVILGGGRKFMFPKGTPDPEYPGDSDQSGVRLDSRNLVEEWLAKYQGTRYVWNREQLMQASQDPAVTRLMGLFEPTEMKYDVNRNASADPSLAEMTEVAVRLLSRNPQGFYLFVEGGRIDQGHHAGTAYLALTEAVMFDSAIEKASQLTNEKDTLTLITADHSHVFAFGGYTLRGTSIFGLAPLNAQDGKSYTSILYGNGPGYVLNSGNRPNVTDAESGDVNYKQQAAVPLSSETHGGEDVAIFARGPQAHLVHGVQEQNYIAHVMAFAGCLEPYTDCGLAPPADENRPTTPVQNSAITMNNVLLSLQLLVSMLLLVGTALVVS", "length": 540 }, "evidence": [ { "id": "RGD:2099", "url": "https://alliancegenome.org/gene/RGD:2099#orthology", "database": "AGR" }, { "id": "MGI:1924018", "url": "https://alliancegenome.org/gene/MGI:1924018#orthology", "database": "AGR" }, { "id": "HGNC:441", "url": "https://alliancegenome.org/gene/HGNC:441#orthology", "database": "AGR" }, { "id": "HGNC:437", "url": "https://alliancegenome.org/gene/HGNC:437#orthology", "database": "AGR" }, { "id": "FB:FBgn0034712", "url": "https://alliancegenome.org/gene/FB:FBgn0034712#orthology", "database": "AGR" }, { "id": "SGD:S000002889", "url": "https://alliancegenome.org/gene/SGD:S000002889#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24822-1", "protein_name": "Intestinal-type alkaline phosphatase", "gene_name": "Iap", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQGPWVLLLLGLRLQLSLSVIPVEEENPAFWNKKAAEALDAAKKLQPIQTSAKNLIIFLGDGMGVPTVTATRILKGQLEGHLGPETPLAMDRFPYMALSKTYSVDRQVPDSASTATAYLCGVKTNYKTIGLSAAARFDQCNTTFGNEVFSVMYRAKKAGKSVGVVTTTRVQHASPSGTYVHTVNRNWYGDADMPASALREGCKDIATQLISNMDINVILGGGRKYMFPAGTPDPEYPNDANETGTRLDGRNLVQEWLSKHQGSQYVWNREQLIQKAQDPSVTYLMGLFEPVDTKFDIQRDPLMDPSLKDMTETAVKVLSRNPKGFYLFVEGGRIDRGHHLGTAYLALTEAVMFDLAIERASQLTSERDTLTIVTADHSHVFSFGGYTLRGTSIFGLAPLNALDGKPYTSILYGNGPGYVGTGERPNVTAAESSGSSYRRQAAVPVKSETHGGEDVAIFARGPQAHLVHGVQEQNYIAHVMASAGCLEPYTDCGLAPPADESQTTTTTRQTTITTTTTTTTTTTTPVHNSARSLGPATAPLALALLAGMLMLLLGAPAES", "length": 559 }, "evidence": [ { "id": "MGI:87984", "url": "https://alliancegenome.org/gene/MGI:87984#orthology", "database": "AGR" }, { "id": "HGNC:441", "url": "https://alliancegenome.org/gene/HGNC:441#orthology", "database": "AGR" }, { "id": "HGNC:437", "url": "https://alliancegenome.org/gene/HGNC:437#orthology", "database": "AGR" }, { "id": "FB:FBgn0034712", "url": "https://alliancegenome.org/gene/FB:FBgn0034712#orthology", "database": "AGR" }, { "id": "RGD:621650", "url": "https://alliancegenome.org/gene/RGD:621650#orthology", "database": "AGR" }, { "id": "SGD:S000002889", "url": "https://alliancegenome.org/gene/SGD:S000002889#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P24823-1", "protein_name": "Alkaline phosphatase, germ cell type", "gene_name": "Alpg", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWGACLLLLGLSLQVCPSVIPVEEENPAFWNRKAAEALDAAKKLKPIQTSAKNLVILMGDGMGVSTVTATRILKGQQQGHLGPETQLAMDRFPHMALSKTYNTDKQIPDSAGTGTAFLCGVKTNMKVIGLSAAARFNQCNTTWGNEVVSVMHRAKKAGKSVGVVTTTSVQHASPAGTYAHTVNRGWYSDAQMPASALQDGCKDISTQLISNMDIDVILGGGRKFMFPKGTPDQEYPTDTKQAGTRLDGRNLVQEWLAKHQGARYVWNRSELIQASLNRSVTHLMGLFEPNDMKYEIHRDPAQDPSLAEMTEVAVRMLSRNPKGFYLFVEGGRIDHGHHETVAYRALTEAVMFDSAVDKADKLTSEQDTMILVTADHSHVFSFGGYTQRGASIFGLAPFKAEDGKSFTSILYGNGPGYKLHNGARADVTEEESSNPTYQQQAAVPLSSETHSGEDVAIFARGPQAHLVHGVQEQNYIAHVMAFAACLEPYTDCGLASPAGQSSAVSPGYMSTLLCLLAGKMLMLMAAAEP", "length": 529 }, "evidence": [ { "id": "MGI:108009", "url": "https://alliancegenome.org/gene/MGI:108009#orthology", "database": "AGR" }, { "id": "HGNC:441", "url": "https://alliancegenome.org/gene/HGNC:441#orthology", "database": "AGR" }, { "id": "HGNC:437", "url": "https://alliancegenome.org/gene/HGNC:437#orthology", "database": "AGR" }, { "id": "FB:FBgn0034712", "url": "https://alliancegenome.org/gene/FB:FBgn0034712#orthology", "database": "AGR" }, { "id": "RGD:2325055", "url": "https://alliancegenome.org/gene/RGD:2325055#orthology", "database": "AGR" }, { "id": "SGD:S000002889", "url": "https://alliancegenome.org/gene/SGD:S000002889#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q24238-1", "protein_name": "Alkaline phosphatase 4", "gene_name": "Alp4", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MHCLVILGFLLGSLVAFSWAGVTTQPPPLIRTLSAGGDIGPQFDVGKTKEPEDAEFWHNVGLRQLEKTIKQAQRVKEDSYQKKARNIIIFIGDGMGISTISAGRIYKGQYLKHGYGEEETLVFDDFPNTGMAKTYNVDKQVPDSAGTATAIFSGSKTHYGAIGMDATRSKKNGQQGRVQSVMEWAQKEGKRTGVVTTTRITHATPAATYAHIYDRDWECDTEVPAESVGFHVDIARQLVENAPGNRFNVILGGGMSPMGILNASEVKTTIFEGPTETICTRGDNRNLPAEWLAHHANDTVPPALVHNRKDLLNVNVKKVDHLMGLFRNNHITYSIAREAGEPSLQEMTETALGILERGDESNGFVLLVEGGRIDQGHHMNYARAALHELYEFDLAIQAAVNNTDPDETLILVTADHSHAVTFNGYALRGADILGTANSHEKNDPMFYETISYANGPGYWDHLANDSRPQNSSNMWMPLKHFTAEERAAPTYRHLATVPRKDETHGGEDVAVFAYGPGSSLIRGVFEQNYLAYVMSYAGCLGPAKDFDDSCEDHKDGQKDRPLDKPNPKRNGATVVGASLIPILTAATAAILRGRGL", "length": 596 }, "evidence": [ { "id": "RGD:2099", "url": "https://alliancegenome.org/gene/RGD:2099#orthology", "database": "AGR" }, { "id": "MGI:1924018", "url": "https://alliancegenome.org/gene/MGI:1924018#orthology", "database": "AGR" }, { "id": "MGI:87984", "url": "https://alliancegenome.org/gene/MGI:87984#orthology", "database": "AGR" }, { "id": "MGI:108009", "url": "https://alliancegenome.org/gene/MGI:108009#orthology", "database": "AGR" }, { "id": "MGI:87983", "url": "https://alliancegenome.org/gene/MGI:87983#orthology", "database": "AGR" }, { "id": "HGNC:437", "url": "https://alliancegenome.org/gene/HGNC:437#orthology", "database": "AGR" }, { "id": "RGD:2325055", "url": "https://alliancegenome.org/gene/RGD:2325055#orthology", "database": "AGR" }, { "id": "RGD:621650", "url": "https://alliancegenome.org/gene/RGD:621650#orthology", "database": "AGR" }, { "id": "RGD:2100", "url": "https://alliancegenome.org/gene/RGD:2100#orthology", "database": "AGR" }, { "id": "SGD:S000002889", "url": "https://alliancegenome.org/gene/SGD:S000002889#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VDG4-1", "protein_name": "Alkaline phosphatase", "gene_name": "Alp5", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFRLLNALLIAIVLVAHPAWSAPECGRTPEECREHRMHPDMPEPERHGKAFRVVDGEDTNAYWRQQGVQFVQQKLASEPNKRQAKNVILFLGDGMGVTTTSAARNLLGGEEKSLSFENFPFTGLSKTYSVDKIVPDSACTATAYLCGVKGQEGTIGVNGQVPRTDCKVMLDESTHVDSIAKWAMEAGKWAGLVTTTRVTHASPSGVYAHIAERDWENDAEVATDCGAGSGINDIAYQLARGEVGSKLKVIMGGGRKHFVDSSLESWGKRTDGLNLIDEFKSASENNVYVTTAAELAAVDVTKTDRLLGLFNDDHLQYLMETTTESSQPTLEQMTRKAIEYMSQNEQGYFLFIEGGRIDQAHHINQARMALNETIEFSKAIAAAQELTSEDDTLLVVTADHSHVFTYAGYSYRGSDVFGKTPVNGHDGKPYMVLSYANGPSYENFYDAETMERKDPTTVVKGDHDDEFPSGVPIDMDSHGGDDVPVYALGPWAHLFTGVYEQSTIPHMMAYASCLGDGHTMCK", "length": 522 }, "evidence": [ { "id": "RGD:2099", "url": "https://alliancegenome.org/gene/RGD:2099#orthology", "database": "AGR" }, { "id": "MGI:1924018", "url": "https://alliancegenome.org/gene/MGI:1924018#orthology", "database": "AGR" }, { "id": "MGI:87984", "url": "https://alliancegenome.org/gene/MGI:87984#orthology", "database": "AGR" }, { "id": "MGI:108009", "url": "https://alliancegenome.org/gene/MGI:108009#orthology", "database": "AGR" }, { "id": "MGI:87983", "url": "https://alliancegenome.org/gene/MGI:87983#orthology", "database": "AGR" }, { "id": "HGNC:438", "url": "https://alliancegenome.org/gene/HGNC:438#orthology", "database": "AGR" }, { "id": "HGNC:441", "url": "https://alliancegenome.org/gene/HGNC:441#orthology", "database": "AGR" }, { "id": "HGNC:437", "url": "https://alliancegenome.org/gene/HGNC:437#orthology", "database": "AGR" }, { "id": "RGD:2325055", "url": "https://alliancegenome.org/gene/RGD:2325055#orthology", "database": "AGR" }, { "id": "RGD:621650", "url": "https://alliancegenome.org/gene/RGD:621650#orthology", "database": "AGR" }, { "id": "RGD:2100", "url": "https://alliancegenome.org/gene/RGD:2100#orthology", "database": "AGR" }, { "id": "SGD:S000002889", "url": "https://alliancegenome.org/gene/SGD:S000002889#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VHD0-1", "protein_name": "Alkaline phosphatase", "gene_name": "phu", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRLQLFFFLGLSVLVSGGESSHDAERRMHPVFSLMGTGSNPIGGGRYKRAMPQIVFDAVRSEERYAEYWQGLAAQTLDQQLESKLRLNTQLARNVMLFIGDGMSIPTITAGRVYLGGEEKQFAFEQFPYVGLSKTYCANMQVADSACTATAYLGGVKANYGTIGVSAAVQFKDCQAQAQAAHHVSSIAAWAQKQGMATGLVTTTSVTHASPAGVYAHLANRNWENDAEVVGDNGDPDLCPDAAAQLINSPVGQKLNVIMGGGRENFLPKGVTDSSGAPGRRLDGRNLIDEWKNQHTNSAQYVENRRELLNLSNHTSRVLGLFAPYHMAYHLDASPAEQPTLEEMVQSAMEILERQSAGRGYFLFVEGGRIDHGHHDTLALRAIDETAEFDKAVRFARSHTSTDDTLIVVSSDHSHTMSLAGYSSRKNDIFGINDGQLAADDLPYATLSYANGPGYDSNYLREGGAVRRKNLRAINMKNKDFMFPSTVPLESETHGGDDVAVFASGPYAQLFTGVFEQHFIPHALGYASCLSDRNMCVDGGVARRPR", "length": 546 }, "evidence": [ { "id": "RGD:2099", "url": "https://alliancegenome.org/gene/RGD:2099#orthology", "database": "AGR" }, { "id": "MGI:1924018", "url": "https://alliancegenome.org/gene/MGI:1924018#orthology", "database": "AGR" }, { "id": "MGI:87984", "url": "https://alliancegenome.org/gene/MGI:87984#orthology", "database": "AGR" }, { "id": "MGI:108009", "url": "https://alliancegenome.org/gene/MGI:108009#orthology", "database": "AGR" }, { "id": "MGI:87983", "url": "https://alliancegenome.org/gene/MGI:87983#orthology", "database": "AGR" }, { "id": "HGNC:438", "url": "https://alliancegenome.org/gene/HGNC:438#orthology", "database": "AGR" }, { "id": "HGNC:441", "url": "https://alliancegenome.org/gene/HGNC:441#orthology", "database": "AGR" }, { "id": "HGNC:437", "url": "https://alliancegenome.org/gene/HGNC:437#orthology", "database": "AGR" }, { "id": "RGD:2325055", "url": "https://alliancegenome.org/gene/RGD:2325055#orthology", "database": "AGR" }, { "id": "RGD:621650", "url": "https://alliancegenome.org/gene/RGD:621650#orthology", "database": "AGR" }, { "id": "RGD:2100", "url": "https://alliancegenome.org/gene/RGD:2100#orthology", "database": "AGR" }, { "id": "SGD:S000002889", "url": "https://alliancegenome.org/gene/SGD:S000002889#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VIW9-1", "protein_name": "alkaline phosphatase", "gene_name": "Alp12", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEKRSGTPINSQKFRKLSDVDMTEVQLNNLDDSSAKETVEIGSFQGNDQSNPVQHTKWFRSRLFLISVVFSALLITAMCIGFVVHYGMSGDVGDMETVSYWPVDLPKEQKEWYDQGIDELQKAVSRQFNRRRAKNVILFVGDGMGPNTVTAARILGVKEEGLLRWEQFPDMGLLKTYCADKQVPDSFSTATALFGGVKVNYETGGVDANVPLGNCSASLKEDHHVQTILKWAQVDGMRTGFVTTTRVTHATPAALYAHVPDRRWECESGMPAEAQGQGCMDIARQLIEQPTGQSINVIMGGGRQMLVSDVTGSAADPLDTWAGQSKDGRDLIRDWRLKKADEGVSHAVVQNNRELWNLNGQDVDYVLGIFANGHLMYDHERDRSDAGMPSLSNMTLKALEVLGNSDKGFLLVVEAGLIDQAHHRGNARKALSEVLELNAAVESTLSFLKSSDRLDETLVIVTADHSHSLTINGHPDRGSSILGLAGNSKTEGTPYTTLTYGTSYQGFQVDPQTQSRKDPTADDITAWEYTQQAAINTDENLHGGSDVTIHADGAMSYLFHGVHEQSYVAHAISYALRIGRFRDSSIAETLAELTPI", "length": 596 }, "evidence": [ { "id": "RGD:2099", "url": "https://alliancegenome.org/gene/RGD:2099#orthology", "database": "AGR" }, { "id": "MGI:1924018", "url": "https://alliancegenome.org/gene/MGI:1924018#orthology", "database": "AGR" }, { "id": "MGI:87984", "url": "https://alliancegenome.org/gene/MGI:87984#orthology", "database": "AGR" }, { "id": "MGI:108009", "url": "https://alliancegenome.org/gene/MGI:108009#orthology", "database": "AGR" }, { "id": "MGI:87983", "url": "https://alliancegenome.org/gene/MGI:87983#orthology", "database": "AGR" }, { "id": "HGNC:438", "url": "https://alliancegenome.org/gene/HGNC:438#orthology", "database": "AGR" }, { "id": "HGNC:441", "url": "https://alliancegenome.org/gene/HGNC:441#orthology", "database": "AGR" }, { "id": "HGNC:437", "url": "https://alliancegenome.org/gene/HGNC:437#orthology", "database": "AGR" }, { "id": "RGD:2325055", "url": "https://alliancegenome.org/gene/RGD:2325055#orthology", "database": "AGR" }, { "id": "RGD:621650", "url": "https://alliancegenome.org/gene/RGD:621650#orthology", "database": "AGR" }, { "id": "RGD:2100", "url": "https://alliancegenome.org/gene/RGD:2100#orthology", "database": "AGR" }, { "id": "SGD:S000002889", "url": "https://alliancegenome.org/gene/SGD:S000002889#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VRM8-1", "protein_name": "alkaline phosphatase", "gene_name": "Alp10", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVKSCLILCFFALLVIQARSDLADDQEHAQHPRLQSSRDFEALDEELDTRFWHDKAQSILADKLAGHKKLNENRAKNVILFLGDGMSVHTIAATRAFMGDSNKQVFFEKFPYLGLSKTYAVNERTPDSANTATAYLTGVKANYGTIGVNAQVQRGDCVTNSSSHVQSIGQWAQEAGKWAGLVTTARVTHASPAGVYAHVSERNWEHDGEIISSKCSPDVNTDIARQLVEWPVGQELRVIMGGGRSYFRDQSQHDETGVSGLRTDGRDLISDWREIKKQQGAEGKYVWSLKGLKETDISKTDYLLGLFDTSHLPYHGDRRRTHYEDAEPSLSDMTEAAIKMLSKNEEGYFLFVESGRIDMAHHATKAMKALEDTEEFAAAVELARKMTDEEDTLIVVTSDHSHTMSINGYPYRRQNILSLAPNLADDELPFTILSYANGPGFDDTYSTKDGRIDLSHADTTSAEFEFQATVPLSSETHGAEDVGVFASGPFEHLFTGNYEQSAIPAMMAYAANIGPFAKDKINEQ", "length": 524 }, "evidence": [ { "id": "RGD:2099", "url": "https://alliancegenome.org/gene/RGD:2099#orthology", "database": "AGR" }, { "id": "MGI:1924018", "url": "https://alliancegenome.org/gene/MGI:1924018#orthology", "database": "AGR" }, { "id": "MGI:87984", "url": "https://alliancegenome.org/gene/MGI:87984#orthology", "database": "AGR" }, { "id": "MGI:108009", "url": "https://alliancegenome.org/gene/MGI:108009#orthology", "database": "AGR" }, { "id": "MGI:87983", "url": "https://alliancegenome.org/gene/MGI:87983#orthology", "database": "AGR" }, { "id": "HGNC:438", "url": "https://alliancegenome.org/gene/HGNC:438#orthology", "database": "AGR" }, { "id": "HGNC:441", "url": "https://alliancegenome.org/gene/HGNC:441#orthology", "database": "AGR" }, { "id": "HGNC:437", "url": "https://alliancegenome.org/gene/HGNC:437#orthology", "database": "AGR" }, { "id": "RGD:2325055", "url": "https://alliancegenome.org/gene/RGD:2325055#orthology", "database": "AGR" }, { "id": "RGD:621650", "url": "https://alliancegenome.org/gene/RGD:621650#orthology", "database": "AGR" }, { "id": "RGD:2100", "url": "https://alliancegenome.org/gene/RGD:2100#orthology", "database": "AGR" }, { "id": "SGD:S000002889", "url": "https://alliancegenome.org/gene/SGD:S000002889#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VRM9-1", "protein_name": "alkaline phosphatase", "gene_name": "Alp9", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLSLKFWIRLGLLTVVWGAAVPGRAPVDEERMHPHLPTSPRLRTISGEETQEFWHSASKKLIREKLEFVRNTKKAKNIILFLGDGMGLATLAAARSYIGGEELKLSFEEFPFTGLSKTYSVDKIVPDSACTSTSYLCGVKANYGTIGVNAHVKRGDCAAMANETNHVFSLGKWAMDAGKAAGLVTTTRVTHASPSGVYAHVADREWENNAVLEEACGELSDGLQDIAVQLIHGEVGSKLKVMLGGGKRSFYSPEHYDKGRRTDGRNLVEEFEALDAGNTFVKTQKKLLNVNATETGRLLGLFSKSHMHYHLEQLADPDNNEPTLEEMTQKAIEVLETEEQGYFLFVEGGKIDISHHETMARIALDETAELSKAVKKAREMTNPEETLIVVTSDHSHTFSVSGYQPRGSDIFGAAKANGKDGKPYLALSYANGKSFQDYYNTETHERVDPTSLPTIGDFDQLFPAMVPLESETHGGEDVGVFASGPWAHLFTGVYEQNTIPHMMAFAACVGDGLTACD", "length": 517 }, "evidence": [ { "id": "RGD:2099", "url": "https://alliancegenome.org/gene/RGD:2099#orthology", "database": "AGR" }, { "id": "MGI:1924018", "url": "https://alliancegenome.org/gene/MGI:1924018#orthology", "database": "AGR" }, { "id": "MGI:87984", "url": "https://alliancegenome.org/gene/MGI:87984#orthology", "database": "AGR" }, { "id": "MGI:108009", "url": "https://alliancegenome.org/gene/MGI:108009#orthology", "database": "AGR" }, { "id": "MGI:87983", "url": "https://alliancegenome.org/gene/MGI:87983#orthology", "database": "AGR" }, { "id": "HGNC:438", "url": "https://alliancegenome.org/gene/HGNC:438#orthology", "database": "AGR" }, { "id": "HGNC:441", "url": "https://alliancegenome.org/gene/HGNC:441#orthology", "database": "AGR" }, { "id": "HGNC:437", "url": "https://alliancegenome.org/gene/HGNC:437#orthology", "database": "AGR" }, { "id": "RGD:2325055", "url": "https://alliancegenome.org/gene/RGD:2325055#orthology", "database": "AGR" }, { "id": "RGD:621650", "url": "https://alliancegenome.org/gene/RGD:621650#orthology", "database": "AGR" }, { "id": "RGD:2100", "url": "https://alliancegenome.org/gene/RGD:2100#orthology", "database": "AGR" }, { "id": "SGD:S000002889", "url": "https://alliancegenome.org/gene/SGD:S000002889#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VXS8-1", "protein_name": "alkaline phosphatase", "gene_name": "Alp11", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLLQLRRLAILFLLHALIPILALSVPMVEQVQPADELLSSHWLRQAQSQLRERLARTKDSIADVRQAKNVVMLLGDGLSITTLTAARILKGQRRGGRGEDAQLAVEQFPFSGLSKTYCIDEQTPDSACTATAYFGGVKTHSGTVGQSGSGERVDSVLQWAQRAGKATGVVTTTRLTDASPAGAYAHVSRRGEELEIARQLVEEEPGRNLNVILGGGLGKFADERRDGKDLLAQWRESNPNGCFSRSLKELRNCTDATGTLLGIFSDSHMSYHLAASKELPRLCDMAAAAIEKLERKSQEDGNGYFVFIEGGRIDHGHHETRVGYALDEMVEFDAAVETVIQMTDPRDTLVVVTADHSHTLSMSGYAKRGTPILGMDAQQRDVNGVPYSTLNYAIGKWQSLDKDGRRESPSKTLSPTSYTPSYIHGRKGVHSGEDVVVFAMGPQSHLFGGVMEQNLLPHIMGYAACLGNGLTLCNQDKDADMIA", "length": 483 }, "evidence": [ { "id": "RGD:2099", "url": "https://alliancegenome.org/gene/RGD:2099#orthology", "database": "AGR" }, { "id": "MGI:1924018", "url": "https://alliancegenome.org/gene/MGI:1924018#orthology", "database": "AGR" }, { "id": "MGI:87984", "url": "https://alliancegenome.org/gene/MGI:87984#orthology", "database": "AGR" }, { "id": "MGI:108009", "url": "https://alliancegenome.org/gene/MGI:108009#orthology", "database": "AGR" }, { "id": "MGI:87983", "url": "https://alliancegenome.org/gene/MGI:87983#orthology", "database": "AGR" }, { "id": "HGNC:438", "url": "https://alliancegenome.org/gene/HGNC:438#orthology", "database": "AGR" }, { "id": "HGNC:441", "url": "https://alliancegenome.org/gene/HGNC:441#orthology", "database": "AGR" }, { "id": "HGNC:437", "url": "https://alliancegenome.org/gene/HGNC:437#orthology", "database": "AGR" }, { "id": "RGD:2325055", "url": "https://alliancegenome.org/gene/RGD:2325055#orthology", "database": "AGR" }, { "id": "RGD:621650", "url": "https://alliancegenome.org/gene/RGD:621650#orthology", "database": "AGR" }, { "id": "RGD:2100", "url": "https://alliancegenome.org/gene/RGD:2100#orthology", "database": "AGR" }, { "id": "SGD:S000002889", "url": "https://alliancegenome.org/gene/SGD:S000002889#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W274-1", "protein_name": "Alkaline phosphatase", "gene_name": "Alp2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MHISQRRCLYPIFLFLLAFVGTALGRVQEVHNVLELTGQKASKLRFSTDVATGKYTPPEEMDPQFWYKLADEEIAKRLQLPQPNSDRAKNVIMFLGDGMPISTVTAARILKGQRQGNTGEESSLSFEKFPYSGLSRTYCANAQVPDSACTATAYLCGVKTNIINIGVSAAVNFNNCTASQDPANRLTSIAEWAQNAGKSTGFVTTTTLTHASPSGAYAKTANRMWQSDTDVTSYGVDASTCVDMATQLVTQTPGKNFEVMFGGGMGKFLPKTTKDSHGKYGERSDGVNLLSRWQGLHDKGVLVTNRKQLLNLDVSAASSIIGTFQSGLMDFHMDADPTYQPTLSELTEVAIKKLSHNENGYFVFIEGGLIDYGNHYTQAGYALDEALEFEKAIQLAREMTNISDTLIVVTADHGHAVSIAGYPGRGTPILGLNQHDTDINGVKYSVLNYAAGPNQYLDEHGQRIPLDDILGPDDAISPSYIDKEIGVHSGEDVGIWASGPQSHLFTGVMQQSTIPHLMAYASCVGSGKQVCGSSGRKT", "length": 538 }, "evidence": [ { "id": "RGD:2099", "url": "https://alliancegenome.org/gene/RGD:2099#orthology", "database": "AGR" }, { "id": "MGI:1924018", "url": "https://alliancegenome.org/gene/MGI:1924018#orthology", "database": "AGR" }, { "id": "MGI:87984", "url": "https://alliancegenome.org/gene/MGI:87984#orthology", "database": "AGR" }, { "id": "MGI:108009", "url": "https://alliancegenome.org/gene/MGI:108009#orthology", "database": "AGR" }, { "id": "MGI:87983", "url": "https://alliancegenome.org/gene/MGI:87983#orthology", "database": "AGR" }, { "id": "HGNC:438", "url": "https://alliancegenome.org/gene/HGNC:438#orthology", "database": "AGR" }, { "id": "HGNC:441", "url": "https://alliancegenome.org/gene/HGNC:441#orthology", "database": "AGR" }, { "id": "HGNC:437", "url": "https://alliancegenome.org/gene/HGNC:437#orthology", "database": "AGR" }, { "id": "RGD:2325055", "url": "https://alliancegenome.org/gene/RGD:2325055#orthology", "database": "AGR" }, { "id": "RGD:621650", "url": "https://alliancegenome.org/gene/RGD:621650#orthology", "database": "AGR" }, { "id": "RGD:2100", "url": "https://alliancegenome.org/gene/RGD:2100#orthology", "database": "AGR" }, { "id": "SGD:S000002889", "url": "https://alliancegenome.org/gene/SGD:S000002889#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W275-1", "protein_name": "Alkaline phosphatase", "gene_name": "Alp7", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKTFVAISLVLCTLVATSLAASIDMPEIHNQFQLVGGSVSTAKTREGNLIDPNAMAKGKPGPEEEKNAQFWYDLAYEEIAKRLEQPQLDKRKAKNVILFLGDGMSLSTVAAARIHKGQLKGNTGEEDSLSFEKFPYTGLSRTYCSNAQVPDSACTATAYLCGVKTNIVALGITAAVSFNNCSGSEDPANQVDSIAAWAQAAGKATGIVTTTTLTHASPSGAYAKTTNRFFESDTDILTYGEGQNDPATCTDIATQLITQAPGKNFDVMLGGGIGKFLPNTITDPFNKKGERSDGVNLLSRWQGLHPGGVLAYNRNQLLSVNVSKITNLIGTFRSGVMSFNKMADPKEEPTLAEMTRKAIEVVSKRDGGYFLFVEGGLIDYGNHFNSPTYSLSETLQFEQAVQEALDITDPEETLIVVTSDHAHPLTISGYPGRGTPILGLNQDDTDVNGVKYATLNYAVGTNQYLDEHGQRIDLTDQIGAEDFIHPSYIHGTIGVHAGDDVGIFATGPQSHLFTGVMQQSTIPHLMAYASCIGNGPTLCDNED", "length": 543 }, "evidence": [ { "id": "RGD:2099", "url": "https://alliancegenome.org/gene/RGD:2099#orthology", "database": "AGR" }, { "id": "MGI:1924018", "url": "https://alliancegenome.org/gene/MGI:1924018#orthology", "database": "AGR" }, { "id": "MGI:87984", "url": "https://alliancegenome.org/gene/MGI:87984#orthology", "database": "AGR" }, { "id": "MGI:108009", "url": "https://alliancegenome.org/gene/MGI:108009#orthology", "database": "AGR" }, { "id": "MGI:87983", "url": "https://alliancegenome.org/gene/MGI:87983#orthology", "database": "AGR" }, { "id": "HGNC:438", "url": "https://alliancegenome.org/gene/HGNC:438#orthology", "database": "AGR" }, { "id": "HGNC:441", "url": "https://alliancegenome.org/gene/HGNC:441#orthology", "database": "AGR" }, { "id": "HGNC:437", "url": "https://alliancegenome.org/gene/HGNC:437#orthology", "database": "AGR" }, { "id": "RGD:2325055", "url": "https://alliancegenome.org/gene/RGD:2325055#orthology", "database": "AGR" }, { "id": "RGD:621650", "url": "https://alliancegenome.org/gene/RGD:621650#orthology", "database": "AGR" }, { "id": "RGD:2100", "url": "https://alliancegenome.org/gene/RGD:2100#orthology", "database": "AGR" }, { "id": "SGD:S000002889", "url": "https://alliancegenome.org/gene/SGD:S000002889#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "alkaline phosphatase activity", "id": "GO:0004035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004035", "evidence": [ { "database": "UniProtKB", "id": "Q9W273", "url": "https://www.uniprot.org/uniprotkb/Q9W273" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9W273", "url": "https://www.uniprot.org/uniprotkb/Q9W273" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9W273", "url": "https://www.uniprot.org/uniprotkb/Q9W273" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "Q9W273", "url": "https://www.uniprot.org/uniprotkb/Q9W273" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "Q9W273", "url": "https://www.uniprot.org/uniprotkb/Q9W273" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" }, { "start_pos": 312, "end_pos": 314, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "15017", "name": "", "equation": "a phosphate monoester + H2O = an alcohol + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P82890-1", "Q24238-1", "P82891-1", "X2JB52-1", "Q9VDG4-1", "Q9VHD0-1", "Q9W273-1", "Q9W274-1", "Q9W275-1", "Q8I0P9-1" ], "evidence": [ { "id": "15017", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/15017" } ] }, { "id": "R-DME-8847875", "name": "ARF1:GTP binds Golgin TRIP11", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VDG4-1", "Q9VIW9-1", "Q9VXS8-1", "Q9W275-1", "P61209-1", "M9PD70-1", "Q9W274-1", "Q24238-1", "Q9VH28-1", "Q9VHD0-1", "Q9VRM9-1", "Q9VRM8-1", "Q9W273-1" ], "evidence": [ { "id": "R-DME-8847875", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8847875" } ] }, { "id": "R-DME-8878787", "name": "ALPI dimer hydrolyses phosphate monoesters", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, plasma membrane", "input_participant_list": [ "R-ALL-8878780" ], "output_participant_list": [ "R-ALL-8878776" ], "enzyme_list": [ "Q9VDG4-1", "Q9VIW9-1", "Q9VXS8-1", "Q9W275-1", "M9PD70-1", "Q9W274-1", "Q24238-1", "Q9VH28-1", "Q9VHD0-1", "Q9VRM9-1", "Q9VRM8-1", "Q9W273-1" ], "evidence": [ { "id": "R-DME-8878787", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8878787" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-8878776", "participant_name": "Alcohol [extracellular region]", "crossref": [ { "id": "C00069", "database": "COMPOUND", "url": "" }, { "id": "30879", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-8878780", "participant_name": "phosphate monoester [extracellular region]", "crossref": [ { "id": "7794", "database": "ChEBI", "url": "" }, { "id": "Orthophosphoric-Monoesters", "database": "AraCyc", 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"https://www.uniprot.org/uniprotkb/Q9W282/entry#names_and_taxonomy" } ] }, { "name": "CG3045-PA", "type": "synonym", "evidence": [ { "id": "NP_611646", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611646" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_611646", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611646" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W282", "url": "https://www.uniprot.org/uniprotkb/Q9W282" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG3045", "url": "https://www.uniprot.org/uniprotkb/Q9W282", "locus": { "chromosome": "2R", "start_pos": 22172803, "end_pos": 22174691, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0034703", "url": "https://www.ensemblgenomes.org/id/FBgn0034703" } ] } } ], "crossref": [ { "id": "FB:FBgn0034703", "url": "https://alliancegenome.org/gene/FB:FBgn0034703", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0034703", "url": "https://bgee.org/?page=gene&gene_id=FBgn0034703", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02569", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02569", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0034703", "url": "https://flybase.org/reports/FBgn0034703", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "37531", "url": "https://www.ncbi.nlm.nih.gov/gene/37531", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001406", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001406", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020094", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020094", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020095", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020095", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020097", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020097", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020103", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020103", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041707", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041707", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG3045", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3045", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YFGWEYN", "url": "https://omabrowser.org/oma/group/YFGWEYN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W282", "url": "https://www.orthodb.org/?gene=Q9W282", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11142", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11142", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11142:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11142:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01416", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01416", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_611646", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611646", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W282", "url": "https://www.uniprot.org/uniprotkb/Q9W282", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W282-1", "url": "https://www.uniprot.org/uniprotkb/Q9W282-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSATNDKKVVINKRLKGLSREALEKLTQTELIDKVIQLEAYNFQLRNLLQKKLSEKDKHDKEYSGLIGNEAEGKVSQVAKTSSKVQKIRKFDWSSAHKRHVLLKITYFGWDYQGFACQEDSNDTIESNLFRALARTCLIESRATSNYHRCGRTDKEVSAFCQVISIDLRSKHPPESQLDPTALSSEIDYCGLLNRVLPKNIQCVAWMPLRSPVYSARFDCVSRTYRYYFPKGDLDIAAMRKACDLLVRHADFRNFCKMDVHNGVTNYMRNLQSARVEACDQTNHTNSGYDMYYLEIQANAFLWHQIRCIMAVLLLVGQKKENPGVISDLLDVESNPCKPQYTPAIGLPLNLFRCDFRDHTTRSVNHPSSGDADEEAMDTAADESNDLNAPEHLERDLTAWIYNEENLQKLIENTQCEWTQFSVKSTMIRNVLQQLENLFEENFKPKEKVLAQVILLQDSVNPRQYQPLLERKRCESLENRIEHFVKKQRLIVKNETETE", "length": 499, "header": "tr|Q9W282-1|Q9W282_DROME Isoform 1 of Pseudouridine synthase I TruA alpha/beta domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG3045 PE=1 SV=1 CANONICAL=Q9W282-1" }, "isoforms": [ { "isoform_ac": "Q9W282-1", "url": "https://www.uniprot.org/uniprotkb/Q9W282/entry#Q9W282-1", "sequence": { "sequence": "MSATNDKKVVINKRLKGLSREALEKLTQTELIDKVIQLEAYNFQLRNLLQKKLSEKDKHDKEYSGLIGNEAEGKVSQVAKTSSKVQKIRKFDWSSAHKRHVLLKITYFGWDYQGFACQEDSNDTIESNLFRALARTCLIESRATSNYHRCGRTDKEVSAFCQVISIDLRSKHPPESQLDPTALSSEIDYCGLLNRVLPKNIQCVAWMPLRSPVYSARFDCVSRTYRYYFPKGDLDIAAMRKACDLLVRHADFRNFCKMDVHNGVTNYMRNLQSARVEACDQTNHTNSGYDMYYLEIQANAFLWHQIRCIMAVLLLVGQKKENPGVISDLLDVESNPCKPQYTPAIGLPLNLFRCDFRDHTTRSVNHPSSGDADEEAMDTAADESNDLNAPEHLERDLTAWIYNEENLQKLIENTQCEWTQFSVKSTMIRNVLQQLENLFEENFKPKEKVLAQVILLQDSVNPRQYQPLLERKRCESLENRIEHFVKKQRLIVKNETETE", "length": 499, "header": "tr|Q9W282-1|Q9W282_DROME Isoform 1 of Pseudouridine synthase I TruA alpha/beta domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG3045 PE=1 SV=1 CANONICAL=Q9W282-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W282", "url": "https://www.uniprot.org/uniprotkb/Q9W282" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W282", "url": "https://www.uniprot.org/uniprotkb/Q9W282" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W282", "url": "https://www.uniprot.org/uniprotkb/Q9W282" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W282", "url": "https://www.uniprot.org/uniprotkb/Q9W282" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W282", "url": "https://www.uniprot.org/uniprotkb/Q9W282" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W282", "url": "https://www.uniprot.org/uniprotkb/Q9W282" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W282", "url": "https://www.uniprot.org/uniprotkb/Q9W282" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W282", "url": "https://www.uniprot.org/uniprotkb/Q9W282" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W282", "url": "https://www.uniprot.org/uniprotkb/Q9W282" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W282", "url": "https://www.uniprot.org/uniprotkb/Q9W282" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W282", "url": "https://www.uniprot.org/uniprotkb/Q9W282" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG3045", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3045", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZYZ1-1", "protein_name": "tRNA pseudouridine(38/39) synthase", "gene_name": "PUS3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MANGSWATDREQLLRRVRDLEEEVKQLQEKLSEGKEGTAVKDTPSTSRKSKKQQQRPFDFSAHGRRHVALRIAYLGWGYQGFASQENTSNTIEEKLFEALKKTRLVDDRQTSNYHRCGRTDKGVSAFGQVRMDLQVPLGMVELRMGLLADGDEPSAHCVTVQVISLDLRSNLSEEKKLNGCTGDSEGKSSKSEEELRYTHILNRVLPPDIRVLAWAPVEPDFSARFSCLKRTYRYFFPCADLDVALMHTAAQRYVGTHDFRNLCKMDVANGVINFQRTILSAQVTWADGGAESGLRDPFRLCQFEVTGQAFLYHQVRCMMAILFLIGQRMEGPEIIDELLDVEKNPRKPQYSMAVEFPLVLYDCEFENIQWHYDREVQEFNVTHLQQLWASYAVKTQVLHSMLRGLDTAPMAAGKDPGNAAPVLWGDLKPPVHNQASSFVEGVRARAYKPLLERPRCEGLESRIQQCLRRGRSQAERAAKRLCTGEGPGGTS", "length": 492 }, "evidence": [ { "id": "Q9W282", "url": "https://omabrowser.org/oma/group/Q9W282/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1N5P3-1", "protein_name": "tRNA pseudouridine(38/39) synthase", "gene_name": "PUS3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAENDVDRIQTEKLLKRVQELEQEVKRLKKEQANNKDSNIRENSSGAGGKPKRAFDFSAHGQRHVALKIAYLGWGYQGFASQENTSNTIEEKLFEALTKTRLVENRQTSNYHRCGRTDKGVSAFGQVISLDLRSHIPKGRDSEHFNLKNEVNDVATEIRYTHILNRVLPPDIRVLAWAPVETSFSARFSCLERTYRYFFPRANLDIVTMNYAAQKYVGTHDFRNLCKMDVANGVINFQRTILSAQVQRVGQNLGEEGWQEPFQLCQFEVTGQAFLYHQVRCMMAVLFLIGQGMEKPEVIDELLNIEKNPQKPQYSMAVEFPLVLYDCKFENIKWIYDREVQEFNVTHLQQLWANHAVKTQMLYSMLQGLDSVALPCGTGPKMDGMIEWRNVKPSVTKQTSAFVEGVKMRTYKPLMDRPKCQGLESRIQHFVRRGRIEHPHLFHEEETKAKRDCSDTLEEENTVFEKPTKRICVDTELKSII", "length": 481 }, "evidence": [ { "id": "Q9W282", "url": "https://omabrowser.org/oma/group/Q9W282/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P31115-1", "protein_name": "tRNA pseudouridine(38/39) synthase", "gene_name": "DEG1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSNFIRRLVGKMKAISTGTNAIVSKKDSIYANWSKEQLIRRITELENANKPHSEKFQHIEDNKKRKISQEEVTRSKAKKAPKKFDFSKHNTRFIALRFAYLGWNYNGLAVQKEYTPLPTVEGTILEAMNKCKLVPSMVLQDYKFSRCGRTDKGVSAMNQVISLEVRSNLTDEEQRDPTNDSREIPYVHVLNQLLPDDIRISAVCLRPPPNFDARFSCVHRHYKYIFNGKNLNIEKMSKAASYFVGERDFRNFCKLDGSKQITNFKRTIISSKILPLSETFYCFDLVGSAFLWHQVRCMMAILFLVGQSLEVPEIVLRLTDIEKTPQRPVYEMANDIPLLLYDCKFPEMDWQEPTVDDYKAIKFTTATEALTLHYELKAAVCNIFKDVLPTANTNNFSKTIINLGDGRGKVVGTYVKLEDRSVMEPVEVVNAKYSKKKNNKNK", "length": 442 }, "evidence": [ { "id": "MGI:1914299", "url": "https://alliancegenome.org/gene/MGI:1914299#orthology", "database": "AGR" }, { "id": "HGNC:25461", "url": "https://alliancegenome.org/gene/HGNC:25461#orthology", "database": "AGR" }, { "id": "FB:FBgn0034703", "url": "https://alliancegenome.org/gene/FB:FBgn0034703#orthology", "database": "AGR" }, { "id": "SGD:S000001895", "url": "https://alliancegenome.org/gene/SGD:S000001895#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q9BZE2-1", "protein_name": "tRNA pseudouridine(38/39) synthase", "gene_name": "PUS3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAYNDTDRNQTEKLLKRVRELEQEVQRLKKEQAKNKEDSNIRENSAGAGKTKRAFDFSAHGRRHVALRIAYMGWGYQGFASQENTNNTIEEKLFEALTKTRLVESRQTSNYHRCGRTDKGVSAFGQVISLDLRSQFPRGRDSEDFNVKEEANAAAEEIRYTHILNRVLPPDIRILAWAPVEPSFSARFSCLERTYRYFFPRADLDIVTMDYAAQKYVGTHDFRNLCKMDVANGVINFQRTILSAQVQLVGQSPGEGRWQEPFQLCQFEVTGQAFLYHQVRCMMAILFLIGQGMEKPEIIDELLNIEKNPQKPQYSMAVEFPLVLYDCKFENVKWIYDQEAQEFNITHLQQLWANHAVKTHMLYSMLQGLDTVPVPCGIGPKMDGMTEWGNVKPSVIKQTSAFVEGVKMRTYKPLMDRPKCQGLESRIQHFVRRGRIEHPHLFHEEETKAKRDCNDTLEEENTNLETPTKRVCVDTEIKSII", "length": 481 }, "evidence": [ { "id": "MGI:1914299", "url": "https://alliancegenome.org/gene/MGI:1914299#orthology", "database": "AGR" }, { "id": "HGNC:25461", "url": "https://alliancegenome.org/gene/HGNC:25461#orthology", "database": "AGR" }, { "id": "FB:FBgn0034703", 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"MAENTDRNQIEKLLNRVKELEQEVERLKKKKEQANNIKDSSIRENSLGSGKAKRAFDFSAHGRRHVALKIAYLGWGYQGFASQENTSNTIEEKLFEALTKTRLVESRQTSNYHRCGRTDKGVSAFGQVISLDLRSQFPTSRDSEDSNLKHEADDLAKEIRYTHILNRVLPADIRVLAWAPVEPSFSARFSCLERTYRYFFPRADLDIATMNYAAQKYVGTHDFRNLCKMDVANGVINFQRTILCAQVQLVAQSPGEERRQEPFQLCQFEVIGQAFLYHQVRCMMAILFLIGQGMEKPEIIDELLNIQKNPQKPQYSMAVEFPLVLYDCKFENTKWIYDHEVQEFNVTHLQQLWANHAVKTHMLYSMLQGLDSVMVTCAAGTKMDEATEWRNIQPPVIKHTSAFVEGVKMRTYKPLMDRPKCQGLESRIRHFVSRGRIEHPHLLHKEEIKARRDCADKEENTVVENPSKRVCIIDAEINSIA", "length": 481 }, "evidence": [ { "id": "MGI:1914299", "url": "https://alliancegenome.org/gene/MGI:1914299#orthology", "database": "AGR" }, { "id": "HGNC:25461", "url": "https://alliancegenome.org/gene/HGNC:25461#orthology", "database": "AGR" }, { "id": "FB:FBgn0034703", "url": "https://alliancegenome.org/gene/FB:FBgn0034703#orthology", "database": "AGR" }, { "id": "SGD:S000001895", "url": "https://alliancegenome.org/gene/SGD:S000001895#orthology", "database": "AGR" }, { "id": "Q9W282", "url": "https://omabrowser.org/oma/group/Q9W282/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "tRNA pseudouridine synthesis", "id": "GO:0031119", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031119", "evidence": [ { "database": "UniProtKB", "id": "Q9W282", "url": "https://www.uniprot.org/uniprotkb/Q9W282" } ], "pmid": "" }, { "name": "mRNA pseudouridine synthesis", "id": "GO:1990481", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990481", "evidence": [ { "database": "UniProtKB", "id": "Q9W282", "url": "https://www.uniprot.org/uniprotkb/Q9W282" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q9W282", "url": "https://www.uniprot.org/uniprotkb/Q9W282" } ], "pmid": "" }, { "name": "pseudouridine synthase activity", "id": "GO:0009982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009982", "evidence": [ { "database": "UniProtKB", "id": "Q9W282", "url": "https://www.uniprot.org/uniprotkb/Q9W282" } ], "pmid": "" }, { "name": "tRNA pseudouridine(38/39) synthase activity", "id": "GO:0160154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160154", "evidence": [ { "database": "UniProtKB", "id": "Q9W282", "url": "https://www.uniprot.org/uniprotkb/Q9W282" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9W282", "url": "https://www.uniprot.org/uniprotkb/Q9W282" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9W282", "url": "https://www.uniprot.org/uniprotkb/Q9W282" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 122, "end_pos": 124, "annotation": "n_glycosylation_sequon" }, { "start_pos": 283, "end_pos": 285, "annotation": "n_glycosylation_sequon" }, { "start_pos": 494, "end_pos": 496, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9W282", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W282" }, { "id": "PF01416", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01416" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Pseudouridine synthase I TruA alpha/beta", "eco_id": "ECO_0000259", "start_pos": 244, "end_pos": 356, "start_aa": "Asp", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 122, "end_pos": 124 }, { "start_pos": 283, "end_pos": 285 }, { "start_pos": 494, "end_pos": 496 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9W286-1", "uniprot_ac": "Q9W286", "uniprot_id": "Q9W286_DROME", "mass": { "chemical_mass": 12651.0, "monoisotopic_mass": 12651.0 }, "refseq": { "ac": "NP_611644", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611644" }, "gene_names": [ { "name": "Dmel\\CG11269", "type": "recommended", "evidence": [ { "id": "Q9W286", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W286" } ] }, { "name": "CG11269", "type": "synonym", "evidence": [ { "id": "NP_611644", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611644" }, { "id": "Q9W286", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W286" } ] }, { "name": "Dmel\\CG11269", "type": "synonym", "evidence": [ { "id": "NP_611644", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611644" } ] }, { "name": "Dmel_CG11269", "type": "synonym", "evidence": [ { "id": "Q9W286", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W286" } ] } ], "protein_names": [ { "name": "CG11269-PA", "type": "synonym", "evidence": [ { "id": "NP_611644", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611644" } ] }, { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "Q9W286", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W286/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_611644", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611644" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W286", "url": "https://www.uniprot.org/uniprotkb/Q9W286" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG11269", "url": "https://www.uniprot.org/uniprotkb/Q9W286", "locus": { "chromosome": "2R", "start_pos": 22139295, "end_pos": 22138895, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0034700", "url": "https://www.ensemblgenomes.org/id/FBgn0034700" } ] } } ], "crossref": [ { "id": "FB:FBgn0034700", "url": "https://alliancegenome.org/gene/FB:FBgn0034700", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0034700", "url": "https://bgee.org/?page=gene&gene_id=FBgn0034700", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0034700", "url": "https://flybase.org/reports/FBgn0034700", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "37527", "url": "https://www.ncbi.nlm.nih.gov/gene/37527", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG11269", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG11269", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VSTRCFV", "url": "https://omabrowser.org/oma/group/VSTRCFV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W286", "url": "https://www.orthodb.org/?gene=Q9W286", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31733", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31733", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "NP_611644", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611644", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W286", "url": "https://www.uniprot.org/uniprotkb/Q9W286", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W286-1", "url": "https://www.uniprot.org/uniprotkb/Q9W286-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFCGRKCCLFCLFMSAWGFLMLNLLGIFFYVQSLMLLESLPLPHHFPSQEAFKEQADEAYQDVSTRCFVAAVFYLGFVFIAIVAIRRDNKRRKRLYKRGPGHLRFRR", "length": 107, "header": "tr|Q9W286-1|Q9W286_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG11269 PE=3 SV=1 CANONICAL=Q9W286-1" }, "isoforms": [ { "isoform_ac": "Q9W286-1", "url": "https://www.uniprot.org/uniprotkb/Q9W286/entry#Q9W286-1", "sequence": { "sequence": "MFCGRKCCLFCLFMSAWGFLMLNLLGIFFYVQSLMLLESLPLPHHFPSQEAFKEQADEAYQDVSTRCFVAAVFYLGFVFIAIVAIRRDNKRRKRLYKRGPGHLRFRR", "length": 107, "header": "tr|Q9W286-1|Q9W286_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG11269 PE=3 SV=1 CANONICAL=Q9W286-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W286", "url": "https://www.uniprot.org/uniprotkb/Q9W286" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W286", "url": "https://www.uniprot.org/uniprotkb/Q9W286" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W286", "url": "https://www.uniprot.org/uniprotkb/Q9W286" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W286", "url": "https://www.uniprot.org/uniprotkb/Q9W286" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W286", "url": "https://www.uniprot.org/uniprotkb/Q9W286" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. 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"https://www.uniprot.org/uniprotkb/Q9W297/entry#names_and_taxonomy" } ] }, { "name": "CG6437-PA", "type": "synonym", "evidence": [ { "id": "NP_611636", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611636" } ] }, { "name": "GlcT-1", "type": "synonym", "evidence": [ { "id": "NP_611636", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611636" } ] }, { "name": "GlcT-PA", "type": "synonym", "evidence": [ { "id": "NP_611636", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611636" } ] }, { "name": "ceramide glucosyltransferase", "type": "synonym", "evidence": [ { "id": "NP_611636", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611636" } ] }, { "name": "glucosylceramide synthase", "type": "synonym", "evidence": [ { "id": "NP_611636", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611636" } ] } ], "function": [], "disease": [ { "disease_id": "DOID:10763", "recommended_name": { "id": "DOID:10763", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries." }, "synonyms": [ { "id": "DOID:10763", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10763", "name": "HTN", "description": "" }, { "id": "DOID:10763", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10763", "name": "hyperpiesia", "description": "" }, { "id": "DOID:10763", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10763", "name": "vascular hypertensive disorder", "description": "" } ], "unlinked_id_list": [ "DOID:13731", "DOID:11130" ], "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W297", "url": "https://www.uniprot.org/uniprotkb/Q9W297" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "GlcT", "url": "https://www.uniprot.org/uniprotkb/Q9W297", "locus": { "chromosome": "2R", "start_pos": 22079381, "end_pos": 22075988, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0067102", "url": "https://www.ensemblgenomes.org/id/FBgn0067102" } ] } } ], "crossref": [ { "id": "FB:FBgn0067102", "url": "https://alliancegenome.org/gene/FB:FBgn0067102", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0067102", "url": "https://bgee.org/?page=gene&gene_id=FBgn0067102", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "GT21", "url": "http://www.cazy.org/GT21.html", "database": "CAZy", "categories": [ "Protein Classification" ] }, { "id": "cd02520", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02520", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0067102", "url": "https://flybase.org/reports/FBgn0067102", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "37516", "url": "https://www.ncbi.nlm.nih.gov/gene/37516", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR025993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG6437", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG6437", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IVWIIDC", "url": "https://omabrowser.org/oma/group/IVWIIDC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W297", "url": "https://www.orthodb.org/?gene=Q9W297", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12726", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12726", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12726:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12726:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13506", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13506", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-9840309", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9840309", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_611636", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611636", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "70243", "url": "https://www.rhea-db.org/rhea/70243", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "70247", "url": "https://www.rhea-db.org/rhea/70247", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q9W297", "url": "https://www.uniprot.org/uniprotkb/Q9W297", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W297-1", "url": "https://www.uniprot.org/uniprotkb/Q9W297-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSHLPLPLYGFAAFFMVFWLGTWMVHVIAICYGRYKLHKKSCKLPTEAQPLPGVSILKPLMGVDPNLQHNLETFFTMDYPLYELLFCVEDKEDPAIQLVERLLAKYPLVDAALFVGGSDVGVNPKINNIHPGYMAAKYDFVMISDSGIKMKDDTLLDMVQNMSEKHALVHQMPFTCDRDGFAATFEKVFFGTVQSRIYLSADVLGINCHTGMSCLLRKAVIDQLGGLRAFGCYLAEDFFIARSVTRLGWKMRISNQPALQNSGLCDIGSFQARLIRWAKLRVAMVPTTILLEPLSECMILGAIAAWSASVLFSWDPLVFYLVHVLCWFLSDWLLLSIVQHGSMPFHKFEFVVGWLFRELTGPYLFLHALWNPAIRWRARTYKLHWGGVAYELNSLASDAANDPLAPQPQPAPTLEPAVVNAGTTGDTLICTGAKQRLLVS", "length": 440, "header": "tr|Q9W297-1|Q9W297_DROME Isoform 1 of ceramide glucosyltransferase OS=Drosophila melanogaster OX=7227 GN=GlcT PE=3 SV=1 CANONICAL=Q9W297-1" }, "isoforms": [ { "isoform_ac": "Q9W297-1", "url": "https://www.uniprot.org/uniprotkb/Q9W297/entry#Q9W297-1", "sequence": { "sequence": "MSHLPLPLYGFAAFFMVFWLGTWMVHVIAICYGRYKLHKKSCKLPTEAQPLPGVSILKPLMGVDPNLQHNLETFFTMDYPLYELLFCVEDKEDPAIQLVERLLAKYPLVDAALFVGGSDVGVNPKINNIHPGYMAAKYDFVMISDSGIKMKDDTLLDMVQNMSEKHALVHQMPFTCDRDGFAATFEKVFFGTVQSRIYLSADVLGINCHTGMSCLLRKAVIDQLGGLRAFGCYLAEDFFIARSVTRLGWKMRISNQPALQNSGLCDIGSFQARLIRWAKLRVAMVPTTILLEPLSECMILGAIAAWSASVLFSWDPLVFYLVHVLCWFLSDWLLLSIVQHGSMPFHKFEFVVGWLFRELTGPYLFLHALWNPAIRWRARTYKLHWGGVAYELNSLASDAANDPLAPQPQPAPTLEPAVVNAGTTGDTLICTGAKQRLLVS", "length": 440, "header": "tr|Q9W297-1|Q9W297_DROME Isoform 1 of ceramide glucosyltransferase OS=Drosophila melanogaster OX=7227 GN=GlcT PE=3 SV=1 CANONICAL=Q9W297-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycosyltransferase-activity" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W297", "url": "https://www.uniprot.org/uniprotkb/Q9W297" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W297", "url": "https://www.uniprot.org/uniprotkb/Q9W297" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W297", "url": "https://www.uniprot.org/uniprotkb/Q9W297" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W297", "url": "https://www.uniprot.org/uniprotkb/Q9W297" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W297", "url": "https://www.uniprot.org/uniprotkb/Q9W297" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W297", "url": "https://www.uniprot.org/uniprotkb/Q9W297" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W297", "url": "https://www.uniprot.org/uniprotkb/Q9W297" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W297", "url": "https://www.uniprot.org/uniprotkb/Q9W297" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W297", "url": "https://www.uniprot.org/uniprotkb/Q9W297" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W297", "url": "https://www.uniprot.org/uniprotkb/Q9W297" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W297", "url": "https://www.uniprot.org/uniprotkb/Q9W297" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG6437", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG6437", "resource": "KEGG Pathway" }, { "id": "R-DME-9840309", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9840309", "resource": "Reactome", "description": "Glycosphingolipid biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "E1C7A5-1", "protein_name": "ceramide glucosyltransferase", "gene_name": "UGCG", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAVLALALEGLAIFGLILFVVLWLMHFMSIIYTRLHLNKKATDKQPYSKLPGVSLLKPLKGVDPNLINNLETFFELDYPKYEVLLCVQDHDDPAIDVCKKLLGKYPNVDARLFIGGKKVGINPKINNLMPGYEVAKYDLIWICDSGIRVTPDTLTDMANQMTEKVGLVHGLPYVADRQGFAATLEQVYFGTSHPRSYISANLTGFKCVTGMSCLMRKDVLDQAGGLIAFAQYIAEDYFMAKAIADRGWKFAMATQVAMQNSGSYSISQFQSRMIRWAKLRINMLPATIICEPISECFVASLVIGWAAHHVFRWDIMVFFMCHCLAWFIFDYIQLRGVQGGALCFSKLDYAVAWFIRESMTIYIFLSALWDPTISWRTGRYRLRCGGTAEEILDV", "length": 394 }, "evidence": [ { "id": "Q9W297", "url": "https://omabrowser.org/oma/group/Q9W297/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "I3LPG3-1", "protein_name": "Ceramide glucosyltransferase", "gene_name": "UGCG", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MALLDLALEGMAVFGFVLFLVLWLMHFMAIIYTRLHLNKKATDKQPYSKLPGVSLLKPLKGVDPNLINNLETFFELDYPKYEVLLCVQDHDDPAIDVCKKLLGKYPNVDARLFIGGKKVGINPKINNLMPGYEVAKYDLIWICDSGIRVIPDTLTDMVNQMTEKVGLVHGLPYVADRQGFAATLEQVYFGTSHPRSYISANVTGFKCVTGMSCLMRKDVLDQAGGLIAFAQYIAEDYFMAKAIADRGWRFAMSTQVAMQNSGSYSISQFQSRMIRWTKLRINMLPATIICEPISECFVASLIIGWAAHHVFRWDIMVFFMCHCLAWFIFDYIQLRGVQGGALCFSKLDYAVAWFIRESMTIYIFLSALWDPTISWRTGRYRLRCGGTAEEILDV", "length": 394 }, "evidence": [ { "id": "Q9W297", "url": "https://omabrowser.org/oma/group/Q9W297/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O88693-1", "protein_name": "Ceramide glucosyltransferase", "gene_name": "Ugcg", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALLDLAQEGMALFGFVLFVVLWLMHFMSIIYTRLHLNKKATDKQPYSKLPGVSLLKPLKGVDPNLINNLETFFELDYPKYEVLLCVQDHDDPAIDVCKKLLGKYPNVDARLFIGGKKVGINPKINNLMPAYEVAKYDLIWICDSGIRVIPDTLTDMVNQMTEKVGLVHGLPYVADRQGFAATLEQVYFGTSHPRSYISANVTGFKCVTGMSCLMRKDVLDQAGGLIAFAQYIAEDYFMAKAIADRGWRFSMSTQVAMQNSGSYSISQFQSRMIRWTKLRINMLPATIICEPISECFVASLIIGWAAHHVFRWDIMVFFMCHCLAWFIFDYIQLRGVQGGTLCFSKLDYAVAWFIRESMTIYIFLSALWDPTISWRTGRYRLRCGGTAEEILDV", "length": 394 }, "evidence": [ { "id": "RGD:621870", "url": "https://alliancegenome.org/gene/RGD:621870#orthology", "database": "AGR" }, { "id": "HGNC:12524", "url": "https://alliancegenome.org/gene/HGNC:12524#orthology", "database": "AGR" }, { "id": "MGI:1332243", "url": "https://alliancegenome.org/gene/MGI:1332243#orthology", "database": "AGR" }, { "id": "FB:FBgn0067102", "url": "https://alliancegenome.org/gene/FB:FBgn0067102#orthology", "database": "AGR" }, { "id": "Q9W297", "url": "https://omabrowser.org/oma/group/Q9W297/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q16739-1", "protein_name": "Ceramide glucosyltransferase", "gene_name": "UGCG", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALLDLALEGMAVFGFVLFLVLWLMHFMAIIYTRLHLNKKATDKQPYSKLPGVSLLKPLKGVDPNLINNLETFFELDYPKYEVLLCVQDHDDPAIDVCKKLLGKYPNVDARLFIGGKKVGINPKINNLMPGYEVAKYDLIWICDSGIRVIPDTLTDMVNQMTEKVGLVHGLPYVADRQGFAATLEQVYFGTSHPRYYISANVTGFKCVTGMSCLMRKDVLDQAGGLIAFAQYIAEDYFMAKAIADRGWRFAMSTQVAMQNSGSYSISQFQSRMIRWTKLRINMLPATIICEPISECFVASLIIGWAAHHVFRWDIMVFFMCHCLAWFIFDYIQLRGVQGGTLCFSKLDYAVAWFIRESMTIYIFLSALWDPTISWRTGRYRLRCGGTAEEILDV", "length": 394 }, "evidence": [ { "id": "RGD:621870", "url": "https://alliancegenome.org/gene/RGD:621870#orthology", "database": "AGR" }, { "id": "HGNC:12524", "url": "https://alliancegenome.org/gene/HGNC:12524#orthology", "database": "AGR" }, { "id": "MGI:1332243", "url": "https://alliancegenome.org/gene/MGI:1332243#orthology", "database": "AGR" }, { "id": "FB:FBgn0067102", "url": "https://alliancegenome.org/gene/FB:FBgn0067102#orthology", "database": "AGR" }, { "id": "Q9W297", "url": "https://omabrowser.org/oma/group/Q9W297/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9R0E0-1", "protein_name": "Ceramide glucosyltransferase", "gene_name": "Ugcg", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLDLAQEGMALFGFVLFVVLWLMHFMSIIYTRLHLNKKATDKQPYSKLPGVSLLKPLKGVDPNLINNLETFFELDYPKYEVLLCVQDHDDPAIEVCKKLLGKYPNVDARLFIGGKKVGINPKINNLMPAYEVAKYDLIWICDSGIRVIPDTLTDMVNQMTERVGLVHGLPYVADRQGFAATLEQVYFGTSHPRSYISANVTGFKCVTGMSCLMRKDVLDQAGGLIAFAQYIAEDYFMAKAIADRGWKFSMSTQVAMQNSGSYSISQFQSRMIRWTKLRINMLPATIICEPISECFVASLIIGWAAHHVFRWDIMVFFMCHCLAWFIFDYIQLRGVQGGTLCFSKLDYAVAWFIRESMTIYIFLSALWDPTISWRAGRYRLRCGGTAEEILDV", "length": 394 }, "evidence": [ { "id": "RGD:621870", "url": "https://alliancegenome.org/gene/RGD:621870#orthology", "database": "AGR" }, { "id": "HGNC:12524", "url": "https://alliancegenome.org/gene/HGNC:12524#orthology", "database": "AGR" }, { "id": "MGI:1332243", "url": "https://alliancegenome.org/gene/MGI:1332243#orthology", "database": "AGR" }, { "id": "FB:FBgn0067102", "url": "https://alliancegenome.org/gene/FB:FBgn0067102#orthology", "database": "AGR" }, { "id": "Q9W297", "url": "https://omabrowser.org/oma/group/Q9W297/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q9W297", "url": "https://www.uniprot.org/uniprotkb/Q9W297" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9W297", "url": "https://www.uniprot.org/uniprotkb/Q9W297" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9W297", "url": "https://www.uniprot.org/uniprotkb/Q9W297" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "Q9W297", "url": "https://www.uniprot.org/uniprotkb/Q9W297" } ], "pmid": "" }, { "name": "glucosylceramide biosynthetic process", "id": "GO:0006679", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006679", "evidence": [ { "database": "UniProtKB", "id": "Q9W297", "url": "https://www.uniprot.org/uniprotkb/Q9W297" } ], "pmid": "" }, { "name": "arthro-series glucosylceramide biosynthetic process", "id": "GO:0140269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140269", "evidence": [ { "database": "UniProtKB", "id": "Q9W297", "url": "https://www.uniprot.org/uniprotkb/Q9W297" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ceramide glucosyltransferase activity", "id": "GO:0008120", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008120", "evidence": [ { "database": "UniProtKB", "id": "Q9W297", "url": "https://www.uniprot.org/uniprotkb/Q9W297" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 161, "end_pos": 163, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "70243", "name": "", "equation": "UDP-alpha-D-xylose + an N-acylsphing-4-enine = a beta-D-xylosyl-(1<->1')-N-acylsphing-4-enine + UDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9W297-1" ], "evidence": [ { "id": "70243", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/70243" } ] }, { "id": "70247", "name": "", "equation": "N-(9Z-octadecenoyl)-sphing-4-enine + UDP-alpha-D-xylose = beta-D-xylosyl-(1<->1')-N-(9Z-octadecenoyl)-sphing-4-enine + UDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9W297-1" ], "evidence": [ { "id": "70247", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/70247" } ] }, { "id": "R-DME-1638104", "name": "UGCG transfers glucose to ceramide", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [ "R-ALL-744227", "R-ALL-9844975" ], "output_participant_list": [], "enzyme_list": [ "Q9W297-1" ], "evidence": [ { "id": "R-DME-1638104", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1638104" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-744227", "participant_name": "UDP-Glc [Golgi lumen]", "crossref": [ { "id": "58885", "database": "ChEBI", "url": "" }, { "id": "ZINC000008215472", "database": "ZINC", "url": "" }, { "id": "C00029", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-9844975", "participant_name": "CERA-d18 [Golgi membrane]", "crossref": [ { "id": "52639", "database": "ChEBI", "url": "" }, { "id": "C00195", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "Q9W297", "gene_name": "GlcT", "activity": [ { "ec_number": "2.4.1.80", "activity": "an N-acylsphing-4-enine + UDP-alpha-D-glucose = a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + UDP + H(+).", "evidence": [ { "id": "Q9W297", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W297" } ] }, { "ec_number": "2.4.1.80", "activity": "", "evidence": [ { "id": "Q9W297", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W297" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.4.1.80", "ec_name": "an N-acylsphing-4-enine + UDP-alpha-D-glucose = a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + UDP + H(+).", "evidence": [ { "id": "2.4.1.80", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.80" }, { "id": "2.4.1.80", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.4.1.80" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 161, "end_pos": 163 } ] }, "class_list": [ "glycogene", "glycosyltransferase" ], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9W2A0-1", "uniprot_ac": "Q9W2A0", "uniprot_id": "Q9W2A0_DROME", "mass": { "chemical_mass": 54116.0, "monoisotopic_mass": 54116.0 }, "refseq": { "ac": "NP_611633", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611633" }, "gene_names": [ { "name": "Dmel\\CG11475", "type": "recommended", "evidence": [ { "id": "Q9W2A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W2A0" } ] }, { "name": "CG11475", "type": "synonym", "evidence": [ { "id": "NP_611633", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611633" }, { "id": "Q9W2A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W2A0" } ] }, { "name": "Dmel\\CG11475", "type": "synonym", "evidence": [ { "id": "NP_611633", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611633" } ] }, { "name": "Dmel_CG11475", "type": "synonym", "evidence": [ { "id": "Q9W2A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W2A0" } ] } ], "protein_names": [ { "name": "Sugar phosphate phosphatase", "type": "recommended", "evidence": [ { "id": "Q9W2A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W2A0/entry#names_and_taxonomy" } ] }, { "name": "2.1.1.-", "type": "synonym", "evidence": [ { "id": "Q9W2A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W2A0/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.-", "type": "synonym", "evidence": [ { "id": "Q9W2A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W2A0/entry#names_and_taxonomy" } ] }, { "name": "CG11475-PA", "type": "synonym", "evidence": [ { "id": "NP_611633", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611633" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_611633", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611633" } ] } ], "function": [ { "annotation": "Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate. Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism. Has also been shown to have O-methyltransferase activity that methylates glutamate residues of target proteins to form gamma-glutamyl methyl ester residues. Possibly methylates PCNA, suggesting it is involved in the DNA damage response.", "evidence": [ { "database": "UniProtKB", "id": "Q9W2A0", "url": "https://www.uniprot.org/uniprotkb/Q9W2A0#function" }, { "database": "UniProtKB", "id": "RU367030", "url": "https://www.uniprot.org/uniprotkb/RU367030#function" }, { "database": "UniProtKB", "id": "ARBA00045980", "url": "https://www.uniprot.org/uniprotkb/ARBA00045980#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W2A0", "url": "https://www.uniprot.org/uniprotkb/Q9W2A0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG11475", "url": "https://www.uniprot.org/uniprotkb/Q9W2A0", "locus": { "chromosome": "2R", "start_pos": 22069725, "end_pos": 22071286, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0034687", "url": "https://www.ensemblgenomes.org/id/FBgn0034687" } ] } } ], "crossref": [ { "id": "FB:FBgn0034687", "url": "https://alliancegenome.org/gene/FB:FBgn0034687", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0034687", "url": "https://bgee.org/?page=gene&gene_id=FBgn0034687", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0034687", "url": "https://flybase.org/reports/FBgn0034687", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "37513", "url": "https://www.ncbi.nlm.nih.gov/gene/37513", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002791", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002791", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036075", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036075", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039763", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039763", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG11475", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG11475", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YCGLPIC", "url": "https://omabrowser.org/oma/group/YCGLPIC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W2A0", "url": "https://www.orthodb.org/?gene=Q9W2A0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12260", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12260", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12260:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12260:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01937", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01937", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_611633", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611633", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "24452", "url": "https://www.rhea-db.org/rhea/24452", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "28002", "url": "https://www.rhea-db.org/rhea/28002", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "35603", "url": "https://www.rhea-db.org/rhea/35603", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q9W2A0", "url": "https://www.uniprot.org/uniprotkb/Q9W2A0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W2A0-1", "url": "https://www.uniprot.org/uniprotkb/Q9W2A0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHSADLTSHTDVTETTNLAAIEQLKEQRFNEKNLIIYNPPGENDELSARFLRSLAFATFKRRSPAFLRDLITFLQDREADIIEQCGDYAHFDLKRTIWSLELLRDDIINNREFQIIRVKSPDTDSWNSFLKGLGEDRRQWFSAIWLHADCYMYRRIWSIFQRSETLKNYDYFGDQKTSIVTNVAPLMRDILVSTKGIKRSQEDFQYLLKLSTWSNHGDLNITRRGAHDKIYKQIAKYDIDLLADQSFDVWQDLIEASAPVYVDIVCDNAGFELFADLLLGEYIIESGLASRVRFHVKAIPWFISDCTHKDFNWLVKFLRKHEFQELNAFGKRIRGYIRDRSFILCDKSYFWTSGHDYSQMKRVQPCLYVYISQASLVIFKGDLNYRKLLGDINNKPTTQFSDCLRGFQPSSVCALRVIKSDIYCGLPICTVEKLSEENPEWMVTGDKAVVQVAIKHRLSSDIIV", "length": 464, "header": "tr|Q9W2A0-1|Q9W2A0_DROME Isoform 1 of Sugar phosphate phosphatase OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG11475 PE=3 SV=1 CANONICAL=Q9W2A0-1" }, "isoforms": [ { "isoform_ac": "Q9W2A0-1", "url": "https://www.uniprot.org/uniprotkb/Q9W2A0/entry#Q9W2A0-1", "sequence": { "sequence": "MHSADLTSHTDVTETTNLAAIEQLKEQRFNEKNLIIYNPPGENDELSARFLRSLAFATFKRRSPAFLRDLITFLQDREADIIEQCGDYAHFDLKRTIWSLELLRDDIINNREFQIIRVKSPDTDSWNSFLKGLGEDRRQWFSAIWLHADCYMYRRIWSIFQRSETLKNYDYFGDQKTSIVTNVAPLMRDILVSTKGIKRSQEDFQYLLKLSTWSNHGDLNITRRGAHDKIYKQIAKYDIDLLADQSFDVWQDLIEASAPVYVDIVCDNAGFELFADLLLGEYIIESGLASRVRFHVKAIPWFISDCTHKDFNWLVKFLRKHEFQELNAFGKRIRGYIRDRSFILCDKSYFWTSGHDYSQMKRVQPCLYVYISQASLVIFKGDLNYRKLLGDINNKPTTQFSDCLRGFQPSSVCALRVIKSDIYCGLPICTVEKLSEENPEWMVTGDKAVVQVAIKHRLSSDIIV", "length": 464, "header": "tr|Q9W2A0-1|Q9W2A0_DROME Isoform 1 of Sugar phosphate phosphatase OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG11475 PE=3 SV=1 CANONICAL=Q9W2A0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W2A0", "url": "https://www.uniprot.org/uniprotkb/Q9W2A0" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W2A0", "url": "https://www.uniprot.org/uniprotkb/Q9W2A0" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2A0", "url": "https://www.uniprot.org/uniprotkb/Q9W2A0" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2A0", "url": "https://www.uniprot.org/uniprotkb/Q9W2A0" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W2A0", "url": "https://www.uniprot.org/uniprotkb/Q9W2A0" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W2A0", "url": "https://www.uniprot.org/uniprotkb/Q9W2A0" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W2A0", "url": "https://www.uniprot.org/uniprotkb/Q9W2A0" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2A0", "url": "https://www.uniprot.org/uniprotkb/Q9W2A0" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2A0", "url": "https://www.uniprot.org/uniprotkb/Q9W2A0" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W2A0", "url": "https://www.uniprot.org/uniprotkb/Q9W2A0" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W2A0", "url": "https://www.uniprot.org/uniprotkb/Q9W2A0" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG11475", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG11475", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A6H630-1", "protein_name": "Damage-control phosphatase 1", "gene_name": "Dcph1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAESPAFLSAKDEGSFAYLTIKDRTPQILTKVIDTLHRHKSEFFEKHGEEGIEAEKKAISLLSKLRNELQTDKPITPLVDKCVDTHIWNQYLEYQRSLLNEGDGEPRWFFSPWLFVECYMYRRIHEAIMQSPPIHDFDVFKESKEENFFESQGSIDALCSHLLQLKPVKGLREEQIQDEFFKLLQISLWGNKCDLSLSGGESSSQKANIINCLQDLKPFILINDTESLWALLSKLKKTVETPVVRVDIVLDNSGFELITDLVLADFLFSSELATEIHFHGKSIPWFVSDVTEHDFNWIVEHMKSSNLESMSTCGACWEAYARMGRWAYHDHAFWTLPHPYCVMPQVAPDLYAELQKAHLILFKGDLNYRKLMGDRKWKFTFPFHQALSGFHPAPLCSIRTLKCELQVGLQPGQAEQLTASDPHWLTTGRYGILQFDGPL", "length": 439 }, "evidence": [ { "id": "FB:FBgn0034687", "url": "https://alliancegenome.org/gene/FB:FBgn0034687#orthology", "database": "AGR" }, { "id": "MGI:1920669", "url": "https://alliancegenome.org/gene/MGI:1920669#orthology", "database": "AGR" }, { "id": "HGNC:17872", "url": "https://alliancegenome.org/gene/HGNC:17872#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050327-51", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050327-51#orthology", "database": "AGR" }, { "id": "RGD:1305235", "url": "https://alliancegenome.org/gene/RGD:1305235#orthology", "database": "AGR" }, { "id": "SGD:S000004629", "url": "https://alliancegenome.org/gene/SGD:S000004629#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q04371-1", "protein_name": "Damage-control phosphatase YMR027W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTIPGRFMTIDKGTFGEYTASTRWPIIIQNAIDDLSKHQETEKSNGTKFEQGEVIKKELKEFRQEIIDRVPLRPFTEEEIKIANVPLSFNEYLKKHPEVNWGAVEWLFSEVYLYRRVNVLFQRQCEWAKFDIFNRLKQSTFESSFYGVVELALRYENLLPQLREMKQNPGNEIDDILKVLFKEFIEISLWGNATDLSLLTNATLEDIKSIQGAKARAASESKIVVNDTEKAWEVLTKARADANSREIRVDFVLDNSGFELYADLMLAAFLLQSGLATKCIFHAKDIPYMVSDVMLKDFDILVHDLRDREFFPSGEPSTKESRALDLFAGEMEKFVSSGKIEFREDSFWTTELDYWNLDANETKYHGSILHKDLQKSNLVIFKGDLNYRKLTGDRKWPRTTKWETAIGPLATNGITSLSLRTCKADVQVALPEGLDAKLSQEWEKENPGRGSWWCCSGKWAVICFCSGIHK", "length": 470 }, "evidence": [ { "id": "FB:FBgn0034687", "url": "https://alliancegenome.org/gene/FB:FBgn0034687#orthology", "database": "AGR" }, { "id": "MGI:1920669", "url": "https://alliancegenome.org/gene/MGI:1920669#orthology", "database": "AGR" }, { "id": "HGNC:17872", "url": "https://alliancegenome.org/gene/HGNC:17872#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050327-51", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050327-51#orthology", "database": "AGR" }, { "id": "RGD:1305235", "url": "https://alliancegenome.org/gene/RGD:1305235#orthology", "database": "AGR" }, { "id": "SGD:S000004629", "url": "https://alliancegenome.org/gene/SGD:S000004629#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q58EM4-1", "protein_name": "Damage-control phosphatase 1", "gene_name": "dcph1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEAEGMLPPQSLSAKFEGSFAYLTVRDRLPTILTKVVDTLHRNKDNFYKEYGEEGTEAEKRAISFLSRLRNELQTDKPVLALTDNAEDTQAWNEYMERQQDLMENGQLVSWFKSPWLYVECYMYRRIQEALYMNPPMHNFDPFKEGKTQSYFESQQAIKYLCTYLQELITNMENMTEIQLRENFLKLIQVSLWGNKCDLSISAGQDNSQKLSPIDSLPDLQRFILVDDSSMVWSTLVASQGSRSSGMKHARVDIILDNAGFELVTDLVLADFLISSGLAKQIRFHGKSIPWFVSDVTKQDFEWTIKQTMAANHKWMSASGVQWKHFMKEGTWSYHDHPFWTLPHEFCDMTVDAANLYSTLQTSDLILFKGDLNYRKLTGDRKWEHTVRFDQALRGFQPAPLCSLRTLKADVQVGLQAGHAEKLSTQDPDWMTNGKYAVVQFSSPHREQ", "length": 448 }, "evidence": [ { "id": "FB:FBgn0034687", "url": "https://alliancegenome.org/gene/FB:FBgn0034687#orthology", "database": "AGR" }, { "id": "MGI:1920669", "url": "https://alliancegenome.org/gene/MGI:1920669#orthology", "database": "AGR" }, { "id": "HGNC:17872", "url": "https://alliancegenome.org/gene/HGNC:17872#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050327-51", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050327-51#orthology", "database": "AGR" }, { "id": "RGD:1305235", "url": "https://alliancegenome.org/gene/RGD:1305235#orthology", "database": "AGR" }, { "id": "SGD:S000004629", "url": "https://alliancegenome.org/gene/SGD:S000004629#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6AYT5-1", "protein_name": "Damage-control phosphatase 1", "gene_name": "Dcph1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAESPAFLSAQDVGSFAYLTIKDRTPQILTKVIDTLHRHKSEFFEKHGEEGVEAEKKAISLLSKLRNELQTDKPIIPLVDKCVDTDIWNQYLEYQRSLLNEGDGEPRWFFSPWLFVECYMYRRIHEAIMQSPPIHDFDVFKESKDENFFESQDSINALCTHLLQLKPITDLGEKQIQDEFFKLLQISLWGNKCDLSLSGGESSSQKADIINSLKDLKPFILVNETESLWALLSKLKKTAEPPAVRVDIVLDNSGFELVTDLVFADFLLSSELATEIHFHGKIIPWFVSDVTVRDFEWIVEHMKGSHLESMSACGAAWEAYVGMKKWVYHDHAFWTLPHPFCAMPQVAPDLYAELQKAGVVLFKGDLNYRKLMGDRKWKFTVPFHQALSGFHPAPLCSIRTLKCELQVGLQPGQAEHLTASDPHWLTTGKYGIFQFDGPL", "length": 439 }, "evidence": [ { "id": "FB:FBgn0034687", "url": "https://alliancegenome.org/gene/FB:FBgn0034687#orthology", "database": "AGR" }, { "id": "MGI:1920669", "url": "https://alliancegenome.org/gene/MGI:1920669#orthology", "database": "AGR" }, { "id": "HGNC:17872", "url": "https://alliancegenome.org/gene/HGNC:17872#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050327-51", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050327-51#orthology", "database": "AGR" }, { "id": "RGD:1305235", "url": "https://alliancegenome.org/gene/RGD:1305235#orthology", "database": "AGR" }, { "id": "SGD:S000004629", "url": "https://alliancegenome.org/gene/SGD:S000004629#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9H993-1", "protein_name": "Damage-control phosphatase 1", "gene_name": "DCPH1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVVPASLSGQDVGSFAYLTIKDRIPQILTKVIDTLHRHKSEFFEKHGEEGVEAEKKAISLLSKLRNELQTDKPFIPLVEKFVDTDIWNQYLEYQQSLLNESDGKSRWFYSPWLLVECYMYRRIHEAIIQSPPIDYFDVFKESKEQNFYGSQESIIALCTHLQQLIRTIEDLDENQLKDEFFKLLQISLWGNKCDLSLSGGESSSQNTNVLNSLEDLKPFILLNDMEHLWSLLSNCKKTREKASATRVYIVLDNSGFELVTDLILADFLLSSELATEVHFYGKTIPWFVSDTTIHDFNWLIEQVKHSNHKWMSKCGADWEEYIKMGKWVYHNHIFWTLPHEYCAMPQVAPDLYAELQKAHLILFKGDLNYRKLTGDRKWEFSVPFHQALNGFHPAPLCTIRTLKAEIQVGLQPGQGEQLLASEPSWWTTGKYGIFQYDGPL", "length": 441 }, "evidence": [ { "id": "FB:FBgn0034687", "url": "https://alliancegenome.org/gene/FB:FBgn0034687#orthology", "database": "AGR" }, { "id": "MGI:1920669", "url": "https://alliancegenome.org/gene/MGI:1920669#orthology", "database": "AGR" }, { "id": "HGNC:17872", "url": "https://alliancegenome.org/gene/HGNC:17872#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050327-51", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050327-51#orthology", "database": "AGR" }, { "id": "RGD:1305235", "url": "https://alliancegenome.org/gene/RGD:1305235#orthology", "database": "AGR" }, { "id": "SGD:S000004629", "url": "https://alliancegenome.org/gene/SGD:S000004629#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9V3Z7-1", "protein_name": "Sugar phosphate phosphatase", "gene_name": "BG:DS03023.2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGWRASTHSDKSTTTDLFEGPTPRHSLLSGRYKQSFAYLTLRTRMPGIMQQIIMRLLSDLPDLVNKYGEEVRKDVKQIVDAVERLKMELNRDRQFLLFHGAEPDKVEWNAFITEMPRPKKSFFRACWLHAECYLYRRIFSFFENSRHLQKYDCFDHLKKEDLMLSEMAMSALARATRGLAKSYDAFSKLLRINLWGNHFEMQIGAFRFTEEDSKDDINVLVKVADIDRILLVDDTTLIWNCLVLASKSSGNRIVDFICDNGGFEFFTDMLLLEYMVDNNLATQVRLHVKAIPWYISDVTRADIEWTLDFLTGHRDECLSALGKKWTHMMNTQKIVIAPTSYFWTGPQPYFVMVESDIELYRLLTTSKLAIFKGDLNYRKLLGDFIWDSTEEFITCLRGFRPTNICALRTVKCEVVCGLSEGLADSLLKNDHNWMISGNYGVIQYTDSLKCSCALPGVDSSEKNTRMPGMVVPPSERSTLTPNHP", "length": 484 }, "evidence": [ { "id": "MGI:1920669", "url": "https://alliancegenome.org/gene/MGI:1920669#orthology", "database": "AGR" }, { "id": "HGNC:17872", "url": "https://alliancegenome.org/gene/HGNC:17872#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050327-51", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050327-51#orthology", "database": "AGR" }, { "id": "RGD:1305235", "url": "https://alliancegenome.org/gene/RGD:1305235#orthology", "database": "AGR" }, { "id": "SGD:S000004629", "url": "https://alliancegenome.org/gene/SGD:S000004629#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W298-1", "protein_name": "Sugar phosphate phosphatase", "gene_name": "Dmel\\CG2921", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MESLSKDPSSEGELPEDEGKTDSEPSKISRLLRTEFDAKYQIVNLQTPLNAFMSGHYKQSFAFFTLRSRLPVILTNVIDTLTRDKSELVAQFASNEFSQAAREELKIIIGLISRLKYELQTDKSFQNFTGEEPDRDVWNNFISNLPDGERSFYKASSLHAECYLHRKLHSFLENSVFLKSYDFFAKVKEQALTDSIDDILALTKYTRRSENSVEVFDELLRINMWSNCNDVATDTDTVKQSNRQVLEKVANTDERVLVNQAAEIWRCLENPKLKKHKQVDFILDNAGYELFSDFILAEFMIEKGLADKVRFHVKAHPWFVTDVTERDFKWTLEYLSEHADYIISLIGKKFLQFIDEGKFELAPISHFWTSPHSFYSMAQMDPDLYSSLQLSKLVVFKGELNYRKLLQDVCWDPTQELSTCLRGFLPSNICVLRRVKSEVISGLPEGVGQALSVKDPRWMVSGSYGVIQFVDGAREFGY", "length": 478 }, "evidence": [ { "id": "MGI:1920669", "url": "https://alliancegenome.org/gene/MGI:1920669#orthology", "database": "AGR" }, { "id": "HGNC:17872", "url": 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"keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, 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Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W2E6", "url": "https://www.uniprot.org/uniprotkb/Q9W2E6" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W2E6", "url": "https://www.uniprot.org/uniprotkb/Q9W2E6" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2E6", "url": "https://www.uniprot.org/uniprotkb/Q9W2E6" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2E6", "url": "https://www.uniprot.org/uniprotkb/Q9W2E6" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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], "protein_names": [ { "name": "CG15671-PA", "type": "synonym", "evidence": [ { "id": "NP_524809", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524809" } ] }, { "name": "Crossveinless 2", "type": "synonym", "evidence": [ { "id": "Q9W2H2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W2H2/entry#names_and_taxonomy" } ] }, { "name": "crossveinless 2", "type": "synonym", "evidence": [ { "id": "NP_524809", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524809" } ] }, { "name": "crossveinless-2", "type": "synonym", "evidence": [ { "id": "NP_524809", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524809" } ] }, { "name": "cv-2-PA", "type": "synonym", "evidence": [ { "id": "NP_524809", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524809" } ] } ], "function": [], "disease": [ { "disease_id": "DOID:2559", "recommended_name": { "id": "DOID:2559", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2559", "name": "opiate dependence", "description": "A drug dependence that involves the continued use of opiate drugs despite despite problems related to use of the substance." }, "synonyms": [ { "id": "DOID:2559", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2559", "name": "Opioid type dependence", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "2559", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2559" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W2H2", "url": "https://www.uniprot.org/uniprotkb/Q9W2H2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "cv-2", "url": "https://www.uniprot.org/uniprotkb/Q9W2H2", "locus": { "chromosome": "2R", "start_pos": 21355015, "end_pos": 21379464, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0000395", "url": "https://www.ensemblgenomes.org/id/FBgn0000395" } ] } } ], "crossref": [ { "id": "FB:FBgn0000395", "url": "https://alliancegenome.org/gene/FB:FBgn0000395", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0000395", "url": "https://bgee.org/?page=gene&gene_id=FBgn0000395", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0000395", "url": "https://flybase.org/reports/FBgn0000395", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "45280", "url": "https://www.ncbi.nlm.nih.gov/gene/45280", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001007", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001007", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052424", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052424", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG15671", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG15671", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WHFANSW", "url": "https://omabrowser.org/oma/group/WHFANSW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W2H2", "url": "https://www.orthodb.org/?gene=Q9W2H2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46698", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46698", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46698:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46698:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00093", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00093", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00094", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00094", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08742", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08742", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_524809", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524809", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W2H2", "url": "https://www.uniprot.org/uniprotkb/Q9W2H2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W2H2-1", "url": "https://www.uniprot.org/uniprotkb/Q9W2H2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCCQSSGQWKFPAQQPRKSLASRRRHTGFRPSTQLLILIAVLLALLQGRTVDAGAGDSLSGVRQSCSNEGEEVQLKNQPQIFTCFKCECQNGFVNCRDTCPPVNDCYILDKSNGTCCRRCKGCSFRGMSYESGSEWNDPEDPCKTYKCVATVVTETIQKCYSQCDNNQLQPPRPGECCPTCQGCKINGQTVAEGHEVDASIDDRCLVCQCRGTQLTCSKKTCPVLPCPMSKQIKRPDECCPRCPQNHSFLPVPGKCLFNKSVYPEKTQFMPDRCTNCTCLNGTSVCQRPTCPILECAPEFQEPDGCCPRCAVAEVRSECSLDGIVYQNNETWDMGPCRSCRCNGGTIRCAQMRCPAVKCRANEELKQPPGECCQRCVETAGTCTVFGDPHFRTFDGKFFSFQGSCKYLLASDCMGKTFHIRLTNEGRGTRRASWAKTVTLSLRNLKVNLGQRMRVKVNGTRVTLPYFVVAGGQNVTIERLANGGAVMLRSEMGLTLEWNGAGFLQVSVPAKFKKRLCGLCGNFNGSSRDDLTGKDGRSHGDDEVWHFANSWKVGGPKSCSRKREFLAATPTCDKRKSNFYCHPLSVPALFGECNERLNPENYKAACRMDVCECPSGDCHCDSFAAYAHECRRLGVQLPDWRSATNCPAGWRRNATLSSFKGNQFYGDPSFSRMKGRRQKNHQLRLQLQQEQQQRSKQGQKGRHKPGGHNQLDRQGHNGLDKDQLQKEFILKHVPSSFLYPRAPDRTPPPLH", "length": 751, "header": "tr|Q9W2H2-1|Q9W2H2_DROME Isoform 1 of Crossveinless 2 OS=Drosophila melanogaster OX=7227 GN=cv-2 PE=4 SV=2 CANONICAL=Q9W2H2-1" }, "isoforms": [ { "isoform_ac": "Q9W2H2-1", "url": "https://www.uniprot.org/uniprotkb/Q9W2H2/entry#Q9W2H2-1", "sequence": { "sequence": "MCCQSSGQWKFPAQQPRKSLASRRRHTGFRPSTQLLILIAVLLALLQGRTVDAGAGDSLSGVRQSCSNEGEEVQLKNQPQIFTCFKCECQNGFVNCRDTCPPVNDCYILDKSNGTCCRRCKGCSFRGMSYESGSEWNDPEDPCKTYKCVATVVTETIQKCYSQCDNNQLQPPRPGECCPTCQGCKINGQTVAEGHEVDASIDDRCLVCQCRGTQLTCSKKTCPVLPCPMSKQIKRPDECCPRCPQNHSFLPVPGKCLFNKSVYPEKTQFMPDRCTNCTCLNGTSVCQRPTCPILECAPEFQEPDGCCPRCAVAEVRSECSLDGIVYQNNETWDMGPCRSCRCNGGTIRCAQMRCPAVKCRANEELKQPPGECCQRCVETAGTCTVFGDPHFRTFDGKFFSFQGSCKYLLASDCMGKTFHIRLTNEGRGTRRASWAKTVTLSLRNLKVNLGQRMRVKVNGTRVTLPYFVVAGGQNVTIERLANGGAVMLRSEMGLTLEWNGAGFLQVSVPAKFKKRLCGLCGNFNGSSRDDLTGKDGRSHGDDEVWHFANSWKVGGPKSCSRKREFLAATPTCDKRKSNFYCHPLSVPALFGECNERLNPENYKAACRMDVCECPSGDCHCDSFAAYAHECRRLGVQLPDWRSATNCPAGWRRNATLSSFKGNQFYGDPSFSRMKGRRQKNHQLRLQLQQEQQQRSKQGQKGRHKPGGHNQLDRQGHNGLDKDQLQKEFILKHVPSSFLYPRAPDRTPPPLH", "length": 751, "header": "tr|Q9W2H2-1|Q9W2H2_DROME Isoform 1 of Crossveinless 2 OS=Drosophila melanogaster OX=7227 GN=cv-2 PE=4 SV=2 CANONICAL=Q9W2H2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W2H2", "url": "https://www.uniprot.org/uniprotkb/Q9W2H2" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W2H2", "url": "https://www.uniprot.org/uniprotkb/Q9W2H2" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2H2", "url": "https://www.uniprot.org/uniprotkb/Q9W2H2" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2H2", "url": "https://www.uniprot.org/uniprotkb/Q9W2H2" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W2H2", "url": "https://www.uniprot.org/uniprotkb/Q9W2H2" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W2H2", "url": "https://www.uniprot.org/uniprotkb/Q9W2H2" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W2H2", "url": "https://www.uniprot.org/uniprotkb/Q9W2H2" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2H2", "url": "https://www.uniprot.org/uniprotkb/Q9W2H2" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2H2", "url": "https://www.uniprot.org/uniprotkb/Q9W2H2" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W2H2", "url": "https://www.uniprot.org/uniprotkb/Q9W2H2" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W2H2", "url": "https://www.uniprot.org/uniprotkb/Q9W2H2" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG15671", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG15671", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1M661-1", "protein_name": "BMP-binding endothelial regulator protein", "gene_name": "Bmper", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLWFSGVRALAERPCRRSPGITCCVLLLLNCSGVPMSLASSFLTGSVAKCENEGEVLQIPFITDNPCIMCVCSNKEVTCKREKCPVLSRDCALAIKQRGACCERCKGCTHEGRTYNSSFKWQSPAEPCALRQCQEGVVTESEVRCVVHCKNPAEHPGACCPTCPGCVFEGVQYREGEEFQPEANKCIKCSCVGGRTQCVREVCPILSCPQHLSHTPSGQCCPKCLGQRKVFDLPFGSCLFRSDVYDNGASFVYDNCTVCTCKDSTMVCKKKCSHPGVCNTDEDACCEECLLRVPPEDVKVCKFGSKIFRDGEMWSSVNCSICACVKGKTECRKKQCVPVSSCPQGKILNRKGCCPICTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKNDARRTRSFSWTKSVELVLGESTVSLQQHLTVRWNGSRIALPCHTPHFHIDLDGYLLKVTTRAGLEISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCNRPQRKPVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYTTFYRSCVTDMCECPVHKNCYCESFLAYTRACQREGIKVHWEPQQSCAATQCKHGAVYDTCGPGCVKTCDNWNEIGPCNKPCIAGCHCPANLVLHKGRCIKPVLCPQR", "length": 685 }, "evidence": [ { "id": "HGNC:24154", "url": "https://alliancegenome.org/gene/HGNC:24154#orthology", "database": "AGR" }, { "id": "MGI:1920480", "url": "https://alliancegenome.org/gene/MGI:1920480#orthology", "database": "AGR" }, { "id": "RGD:1563373", "url": "https://alliancegenome.org/gene/RGD:1563373#orthology", "database": "AGR" }, { "id": "FB:FBgn0000395", "url": "https://alliancegenome.org/gene/FB:FBgn0000395#orthology", "database": "AGR" }, { "id": "Q9W2H2", "url": "https://omabrowser.org/oma/group/Q9W2H2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8CJ69-1", "protein_name": "BMP-binding endothelial regulator protein", "gene_name": "Bmper", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLWFFSVRALAERPCRRSPGITCCVLLLLNCSGVPMSLASSFLTGSVAKCENEGEVLQIPFITDNPCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCERCKGCTHEGRTYNSSFKWQTPAEPCVLRQCQEGVVTESEVRCVVHCKNPAEHQGACCPTCPGCVFEGVQYREGEEFQPEGNKCITCSCVGGRTQCVREVCPILSCPQHLSHTPSGQCCPKCLGQRKVFDLPFGSCLFRSDVYDNGASFVYDNCTVCTCKDSTMVCKKKCSHPGVCNSDEDACCEDCLLRVPPEDIKVCKFGSKIFRDGEMWSSVNCSICACVKGKTECRKKQCVPVSSCPQGKILNRKGCCPICTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKNDARRTRSFSWTKSVELMLGESTVSLQQHLTVRWNGSRIALPCHTPHFHIDLDGYLLKVTTRAGLEISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCNRPQRKPVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYTTFYRSCVTDMCECPVHKNCYCESFLAYTRACQREGIKVHWEPQQSCAATQCKHGAVYDTCGPGCVKTCDNWNEIGPCNKPCIAGCHCPANLVLHKGRCIKPVLCPQR", "length": 685 }, "evidence": [ { "id": "HGNC:24154", "url": "https://alliancegenome.org/gene/HGNC:24154#orthology", "database": "AGR" }, { "id": "MGI:1920480", "url": "https://alliancegenome.org/gene/MGI:1920480#orthology", "database": "AGR" }, { "id": "RGD:1563373", "url": "https://alliancegenome.org/gene/RGD:1563373#orthology", "database": "AGR" }, { "id": "FB:FBgn0000395", "url": "https://alliancegenome.org/gene/FB:FBgn0000395#orthology", "database": "AGR" }, { "id": "Q9W2H2", "url": "https://omabrowser.org/oma/group/Q9W2H2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N8U9-1", "protein_name": "BMP-binding endothelial regulator protein", "gene_name": "BMPER", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLWFSGVGALAERYCRRSPGITCCVLLLLNCSGVPMSLASSFLTGSVAKCENEGEVLQIPFITDNPCIMCVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTYNSSFKWQSPAEPCVLRQCQEGVVTESGVRCVVHCKNPLEHLGMCCPTCPGCVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPFGSCLFRSDVYDNGSSFLYDNCTACTCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSSINCTICACVKGRTECRNKQCIPISSCPQGKILNRKGCCPICTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKNDARRTRSFSWTKSVELVLGESRVSLQQHLTVRWNGSRIALPCRAPHFHIDLDGYLLKVTTKAGLEISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCNRPQRKPVPELCQGTVKVKLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTDMCECPVHKNCYCESFLAYTRACQREGIKVHWEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGPCNKPCVAGCHCPANLVLHKGRCIKPVLCPQR", "length": 685 }, "evidence": [ { "id": "HGNC:24154", "url": "https://alliancegenome.org/gene/HGNC:24154#orthology", "database": "AGR" }, { "id": "MGI:1920480", "url": "https://alliancegenome.org/gene/MGI:1920480#orthology", "database": "AGR" }, { "id": "RGD:1563373", "url": "https://alliancegenome.org/gene/RGD:1563373#orthology", "database": "AGR" }, { "id": "FB:FBgn0000395", "url": "https://alliancegenome.org/gene/FB:FBgn0000395#orthology", "database": "AGR" }, { "id": "Q9W2H2", "url": "https://omabrowser.org/oma/group/Q9W2H2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q9W2H2", "url": "https://www.uniprot.org/uniprotkb/Q9W2H2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "heparan sulfate proteoglycan binding", "id": "GO:0043395", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043395", "evidence": [ { "database": "UniProtKB", "id": "Q9W2H2", "url": "https://www.uniprot.org/uniprotkb/Q9W2H2" } ], "pmid": "" }, { "name": "BMP 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"https://www.uniprot.org/uniprotkb/Q9W2H2" } ], "pmid": "" }, { "name": "imaginal disc-derived wing morphogenesis", "id": "GO:0007476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007476", "evidence": [ { "database": "UniProtKB", "id": "Q9W2H2", "url": "https://www.uniprot.org/uniprotkb/Q9W2H2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 113, "end_pos": 115, "annotation": "n_glycosylation_sequon" }, { "start_pos": 246, "end_pos": 248, "annotation": "n_glycosylation_sequon" }, { "start_pos": 259, "end_pos": 261, "annotation": "n_glycosylation_sequon" }, { "start_pos": 276, "end_pos": 278, "annotation": "n_glycosylation_sequon" }, { "start_pos": 281, "end_pos": 283, "annotation": "n_glycosylation_sequon" }, { "start_pos": 329, "end_pos": 331, "annotation": "n_glycosylation_sequon" }, { "start_pos": 458, "end_pos": 460, "annotation": "n_glycosylation_sequon" }, { "start_pos": 474, "end_pos": 476, "annotation": "n_glycosylation_sequon" }, { "start_pos": 524, "end_pos": 526, "annotation": "n_glycosylation_sequon" }, { "start_pos": 653, "end_pos": 655, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9W2H2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W2H2" }, { "id": "PS50184", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50184" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWFC", "eco_id": "ECO_0000259", "start_pos": 182, "end_pos": 244, "start_aa": "Gln", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q9W2H2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W2H2" }, { "id": "PS51233", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51233" } ], "ann_type": "Domain_Extent_Annotation", 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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"authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9W2H3-1", "uniprot_ac": "Q9W2H3", "uniprot_id": "Q9W2H3_DROME", "mass": { "chemical_mass": 29681.0, "monoisotopic_mass": 29681.0 }, "refseq": { "ac": "NP_611582", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611582" }, "gene_names": [ { "name": "Dmel\\CG17974", "type": "recommended", "evidence": [ { "id": "Q9W2H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W2H3" } ] }, { "name": "CG17974", "type": "synonym", "evidence": [ { "id": "NP_611582", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611582" }, { "id": "Q9W2H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W2H3" } ] }, { "name": "Dmel\\CG17974", "type": "synonym", "evidence": [ { "id": "NP_611582", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611582" } ] }, { "name": "Dmel_CG17974", "type": "synonym", "evidence": [ { "id": "Q9W2H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W2H3" } ] } ], "protein_names": [ { "name": "Venom allergen-1", "type": "recommended", "evidence": [ { "id": "Q9W2H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W2H3/entry#names_and_taxonomy" } ] }, { "name": "CG17974-PA", "type": "synonym", "evidence": [ { "id": "NP_611582", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611582" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_611582", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611582" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W2H3", "url": "https://www.uniprot.org/uniprotkb/Q9W2H3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG17974", "url": "https://www.uniprot.org/uniprotkb/Q9W2H3", "locus": { "chromosome": "2R", "start_pos": 21348945, "end_pos": 21350578, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0034624", "url": "https://www.ensemblgenomes.org/id/FBgn0034624" } ] } } ], "crossref": [ { "id": "FB:FBgn0034624", "url": "https://alliancegenome.org/gene/FB:FBgn0034624", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0034624", "url": "https://bgee.org/?page=gene&gene_id=FBgn0034624", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05380", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05380", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0034624", "url": "https://flybase.org/reports/FBgn0034624", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "37441", "url": "https://www.ncbi.nlm.nih.gov/gene/37441", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR014044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034763", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034763", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035940", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035940", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG17974", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG17974", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VGCSIMR", "url": "https://omabrowser.org/oma/group/VGCSIMR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W2H3", "url": "https://www.orthodb.org/?gene=Q9W2H3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF00188", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00188", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_611582", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611582", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W2H3", "url": "https://www.uniprot.org/uniprotkb/Q9W2H3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W2H3-1", "url": "https://www.uniprot.org/uniprotkb/Q9W2H3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSPLICLAIFQLIFQLILAKDYSWCDPDLCGNGVRHIACRTTGNFHRRCQPDAVQVDVSRHKADFLHAHNKRRNFLALGKVPGYYPAARMATMVWDDELQYLSMLNTRTCKLDHDDCHNTYRYANSGQNLCAVWRPRSPHVNVTSLVEECLGLWFNEFDLIDSSFIDSFKVTPIFEDYGHFAELSVDKNFAVGCSIMRFTRPDYPSVYIYNFICNYASLYALGAPVYETGRAASRCTTGKSHFYPGLCSTREVYDPNW", "length": 259, "header": "tr|Q9W2H3-1|Q9W2H3_DROME Isoform 1 of Venom allergen-1 OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG17974 PE=3 SV=2 CANONICAL=Q9W2H3-1" }, "isoforms": [ { "isoform_ac": "Q9W2H3-1", "url": "https://www.uniprot.org/uniprotkb/Q9W2H3/entry#Q9W2H3-1", "sequence": { "sequence": "MSSPLICLAIFQLIFQLILAKDYSWCDPDLCGNGVRHIACRTTGNFHRRCQPDAVQVDVSRHKADFLHAHNKRRNFLALGKVPGYYPAARMATMVWDDELQYLSMLNTRTCKLDHDDCHNTYRYANSGQNLCAVWRPRSPHVNVTSLVEECLGLWFNEFDLIDSSFIDSFKVTPIFEDYGHFAELSVDKNFAVGCSIMRFTRPDYPSVYIYNFICNYASLYALGAPVYETGRAASRCTTGKSHFYPGLCSTREVYDPNW", "length": 259, "header": "tr|Q9W2H3-1|Q9W2H3_DROME Isoform 1 of Venom allergen-1 OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG17974 PE=3 SV=2 CANONICAL=Q9W2H3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, 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"type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W2H3", "url": "https://www.uniprot.org/uniprotkb/Q9W2H3" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2H3", "url": "https://www.uniprot.org/uniprotkb/Q9W2H3" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2H3", "url": 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Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W2H3", "url": "https://www.uniprot.org/uniprotkb/Q9W2H3" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W2H3", "url": "https://www.uniprot.org/uniprotkb/Q9W2H3" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi 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"categories": [ "Protein Classification" ] }, { "id": "PTHR48043:SF60", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48043:SF60", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00201", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00201", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-9753281", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9753281", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-9757110", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9757110", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-9840309", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9840309", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001036565", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001036565", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "21032", 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UDP-glucuronosyltransferase OS=Drosophila melanogaster OX=7227 GN=Ugt49C1 PE=3 SV=3 CANONICAL=Q9W2J3-1" }, "isoforms": [ { "isoform_ac": "Q9W2J3-1", "url": "https://www.uniprot.org/uniprotkb/Q9W2J3/entry#Q9W2J3-1", "sequence": { "sequence": "MQFPLLFGLLLTGTLYSQLELAEGSKILAVYAFPGKSHFMMHTALIRELVESGHQVTMVTAFSLEKEQLGSNYTEILIEPVYDFWHDVKLNFGAQHLFELTRMTNYDFLKMLEIIGLKTTEHALRQPKVRSLIHAEQKEGVFDLLLAEQFYQEAFLALAHLYKIPVVTTSTLGYENHMSQMMGLITPWSFVPHGFMPFTDRMSFLERVKNSYASFYEDMDRLLNYFPKMDAVAREFFGPVLTEVPKVKHMERQISVMLLNSHAPLTTARPTVDAMVPVGGMHIYPPKPLPADMQALLDGATEGAIFFSLGSNVQSKDMPVEMLRLFLQVFGSLKQRVLWKFEDESISQLPDNVMVRKWLPQADILAHRHVKVFITHGGLFGTQEGVHYAVPMLGIPFYCDQHLNMNKAVLGGYAISLHFQSITEEILRHSLDQLIHNVTYKENVQRVSDIFRDRPLEPRKSAVYWIEYVIRHRGASHMRSAGLDLNWFQFYLLDVIAFVAIIALAGVMALSLAIRLLMGSNKKHRKAKQN", "length": 530, "header": "tr|Q9W2J3-1|Q9W2J3_DROME Isoform 1 of UDP-glucuronosyltransferase OS=Drosophila melanogaster OX=7227 GN=Ugt49C1 PE=3 SV=3 CANONICAL=Q9W2J3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycosyltransferase-activity" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W2J3", "url": "https://www.uniprot.org/uniprotkb/Q9W2J3" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W2J3", "url": "https://www.uniprot.org/uniprotkb/Q9W2J3" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2J3", "url": "https://www.uniprot.org/uniprotkb/Q9W2J3" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2J3", "url": "https://www.uniprot.org/uniprotkb/Q9W2J3" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W2J3", "url": "https://www.uniprot.org/uniprotkb/Q9W2J3" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W2J3", "url": "https://www.uniprot.org/uniprotkb/Q9W2J3" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W2J3", "url": "https://www.uniprot.org/uniprotkb/Q9W2J3" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2J3", "url": "https://www.uniprot.org/uniprotkb/Q9W2J3" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2J3", "url": "https://www.uniprot.org/uniprotkb/Q9W2J3" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W2J3", "url": "https://www.uniprot.org/uniprotkb/Q9W2J3" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W2J3", "url": "https://www.uniprot.org/uniprotkb/Q9W2J3" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG15661", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG15661", "resource": "KEGG Pathway" }, { "id": "R-DME-9753281", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9753281", "resource": "Reactome", "description": "Paracetamol ADME" }, { "id": "R-DME-9757110", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9757110", "resource": "Reactome", "description": "Prednisone ADME" }, { "id": "R-DME-9840309", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9840309", "resource": "Reactome", "description": "Glycosphingolipid biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K4R2-1", "protein_name": "glucuronosyltransferase", "gene_name": "Ugt3a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "SLSLSLSLSLTKLLRSKEIPPCRREGTHTIFIEHNIIPNSVKKLLKIFVLFIYLFVYYRFEHHTIVKIHRHFGDLCNHLLSRKDIMEFLKNANFDLVLFESVDYCSSLIVEKLGKQFVLFLAFQLGFMDFELQRVPLSYVPVYGSGLTDQMDFWGRVKNFLMFFDLSRKQREILSQYDSTIQEHFAEGSRPVLSDLLLKAELWFVNCDFAFEFARPLFPNIVYVGGLLDKPVQSIPQDLENFITQFGDSGFVLVALGTVATKFQTKEIIKEMNNAFAHLPQGVIWACKDSHWPKDVTLAPNVKIMDWLPQTDLLAHPSIRLFVTHGGMNSVNEAIQHGVPMVGILFFSDQPENMIRVEAKTIGVSIQIQTLKAETFARTMKEVIEDKRYKSAAMASKIIRHSHPLTPSQRLEGWIDHILQTGGAAHLKPYAFQQPWHEQYLLDVFLFLLGLTLGTVWLCVKVLGAVMRYLSGARKAKQT", "length": 479 }, "evidence": [ { "id": "MGI:2146055", "url": "https://alliancegenome.org/gene/MGI:2146055#orthology", "database": "AGR" }, { "id": "FB:FBgn0034605", "url": "https://alliancegenome.org/gene/FB:FBgn0034605#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-23", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-23#orthology", "database": "AGR" }, { "id": "RGD:1564365", "url": "https://alliancegenome.org/gene/RGD:1564365#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M1NB90-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "ugt5a2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MHSHIHLGLFLLLCVLSRSYAGKLLVVPVEGSHWVNMKVLIVELHSRGHSITVVRGSSSWYIEEQSPLYTSITVDNGVFDDDFMEKFLPHLLKIQRQGKSFWNEMALADEMIHFVTETHKQSCNMTAILFENETLMNSLKDAAYDVVLTDPAYGSGVLLAHRLGLPLVYNVRWTVYGEAHFDIAPSPLSYVPVSGLQLTDKMTFSQRVMNMMTYIMIRYKYSKNFGSPYQELTQKYFGPNVNFFSLLQDADLWLMRNDFTFEFPRPTMPNVVYMGGFQCKPAKPLPGDLEEFVQSSGEHGVIMMSLGTVFGQLLSELNDEIAAAFAQLPQKVIWRYTGPRPANLGNNTLIVNWLPQNDLLGHPKTKLFVAHGGTNGLQEAIYHGVPIVGLPLAFDQPDNLSRMRAKGTAKIVEFATLDRAVFLEALKEVLHNPSYRENMQRLSKLHHDQPMKPLDRAIFWIEFVMRNKGAPHLRAQSFRMSWIEYQSIDVILTLMLMVLVFVLLTVYTMKYFCLCLFRKKVKRE", "length": 524 }, "evidence": [ { "id": "FB:FBgn0034605", "url": "https://alliancegenome.org/gene/FB:FBgn0034605#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061103-373", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061103-373#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1NVN7-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "ugt1a5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASVLLFCLFCLASAKAGKILVVPSDGSHWMGIKPLVEELGRRGNQVVVVIPEASLSMGPSQHTTTLTYPVPYTKAQIQDHISASVTNLISTHVSTDLARFQSFINTMDLLSNLITRNVEGLLLNKDLMKKLQDYNFDVILTDPFETVGVIAAEYLSIPTIYIQTSHPCGADTLASQCPSPPSYVPQRLTHFSDRMNLWQRSVNFVRTLIQPMACRRMFTRADEIASRVLQRKTSIMDIMGRAALWFVHSDFALEFPHPLMPNMIIVGGMDNRKAEPLSQELEEFVNGSGEHGFVVFTLGSMVSQLPEAKAREFFEAFRQIPQRVLWRYTGPVPENAPKNVKLMKWLPQNDLLGHPKVRAFVTHGGSHGIYEGICNGVPMVMLPLFGDQGDNAQRLVSRGVAESLTIYDVTSEKLLVALKKVINDKSYKEKMMKLSAIHRDRPIEPLDLAVFWTEFVMRHKGAEHLRPAAHDLNWIQYHSLDVIGFLLLILLTVIFVTVKSCMFCFRKCFKKSQKKKKA", "length": 519 }, "evidence": [ { "id": "MGI:2137698", "url": "https://alliancegenome.org/gene/MGI:2137698#orthology", "database": "AGR" }, { "id": "MGI:3576090", "url": "https://alliancegenome.org/gene/MGI:3576090#orthology", "database": "AGR" }, { "id": "MGI:3580629", "url": "https://alliancegenome.org/gene/MGI:3580629#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1NX95-1", "protein_name": "glucuronosyltransferase", "gene_name": "ugt2a1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSPRGSTGVFLLLALLLNQNLLCVSGGKILVWPAEFSHWLNIKVILDVLIERGHNITVVTHTATPSVQTTPSAGYNAEILQVPYTKQEIVDNLERMLKYWTHDLPNDNIITASLKIHEMITTATAQNKITCNALFSRADLLEKWKMEKFDVILADPLYICGEILAQKLDIPLIFSLRFTFGNTLERLCGQMPAPPSYVPAVASEKTDQMDFIDRLKNFLFYGMQDFLFYLVTKFKWDHYYSEVLGKPTTMCETMGKADIWLIRTYWDFEYPRPFPPNFKFVGGLHCKPAKPLSKEMEEFVQSSGDHGVVVFSLGSMIKNLTSERANTIAAALGQIPQKVVWRYSGKTPETLAPNTKIYDWIPQNDLLGHPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFADQPDNLLHMKTKGAAVVLDINTLESKDLVDALKTVLNNPSYKESIMRLSRIHHDQPMKPLDQAVYWIEFVMRNKGAKHLRVQAHELSWYQYHCLDVAAFLLSIAALITFLWVKACCFLFRRCVRKTRPERKTQKSKNE", "length": 539 }, "evidence": [ { "id": "FB:FBgn0034605", "url": "https://alliancegenome.org/gene/FB:FBgn0034605#orthology", "database": "AGR" }, { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080721-20", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080721-20#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" }, { "id": "RGD:708541", "url": "https://alliancegenome.org/gene/RGD:708541#orthology", "database": "AGR" }, { "id": "RGD:628623", "url": "https://alliancegenome.org/gene/RGD:628623#orthology", "database": "AGR" }, { "id": "RGD:620895", "url": "https://alliancegenome.org/gene/RGD:620895#orthology", "database": "AGR" }, { "id": "HGNC:28183", "url": "https://alliancegenome.org/gene/HGNC:28183#orthology", "database": "AGR" }, { "id": "HGNC:12545", "url": "https://alliancegenome.org/gene/HGNC:12545#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB12ZY70-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "ugt2b6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRPLACFLSLLSLLSAGECGNVLVWFTEGSHWINMKIVLETLIDRGHDVTVLVPDASLFMKANASDRFSYQPFNVSMDEQEMKVFIEEFLYFSLYEMDQLNFFQMQSKVYEFTSKLQDMSISYCDGVLKSPGLLDKLRKHKFDVVFSDPIYQCSDIVAEELNVPLVYTFRFSLAHAAERMCGQIPAPPSYVPGAMSKLTDKMSFTERIYNMLFYLSQDAFAIFAWKKIDNYYTEYFGRPTSYCEMMGRADIWLIRTYWDFEFPRPFVPNFKYIGGLHCTPAKPLPKDMEEFVQSSGEDGIVVFTLGSLVGKVPKEISNRIASALAQIPQKVLWRYGGEKPDTLGENTRIYKWIPQNDLLGHPKTRAFITHGGTNGVYEAIYHGVPMVGIPLFGDQPDNMVHMTTRGAAVVVDSIKSMQPQELVDKLNTVINDPSYKENAMRLSRIHHDRPMKPLDESVFWIEFVMRNKGAKHLRVEAHNLTWYQYHCLDVFAFLTTVLTLVLYICFKMAKFFIMRCCFRSKRKSKKE", "length": 527 }, "evidence": [ { "id": "FB:FBgn0034605", "url": "https://alliancegenome.org/gene/FB:FBgn0034605#orthology", "database": "AGR" }, { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" }, { "id": "HGNC:28183", "url": "https://alliancegenome.org/gene/HGNC:28183#orthology", "database": "AGR" }, { "id": "HGNC:12545", "url": "https://alliancegenome.org/gene/HGNC:12545#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TA02-1", "protein_name": "UDP glucuronosyltransferase 5 family, polypeptide C3 isoform X2", "gene_name": "ugt5c3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFSCNLNPCNSIASRMAQLSKNTFSVSLWITVMIIFGSLCDGGKILVAPLEGSHWVNMDILIKALHGQGHTVDVIRNTNSWFVKENSTYYNSITIPDSKGMDEEFVEDVLTKKIDYERGKGSWLGGVQLFLDVSKAVYESHKLVCRLITNIFESEDILKALQEKKYDLMLTDPGWGTGIILAHKLKLPMVYNVRWTTPGEGHFDIAPSPMSYIPLTGSGNTDKMSFFQRVINVFYYLLLDFQCSRFNVPQYQALCDKYFDPPVDFYKLLQGADLWLMRVDFVFEFPRPTMPNIIYTGGFQCTPAKPLPHDLEDFMQSSGDHGVIVMSLGSFISVLPDYVSSEIAAAFARLPQKVIWRYTGKKPSTLGNNTLLVDWMPQKDLLGHPKTKLFIAHGGTNGVQEALYHGVPVIGIPFFFDQYDNLIRLQARGGAKIVSLAELGENSLHAAIQEVINEPSYRLNMQKLSYLHRDKPVEPLDSAIFWIEFVMRHKGAAHLRTESYKMPWYSYHSVDVSVTLIAVVLIFIYSMFVTVRYLCIKCCSRKRKTE", "length": 546 }, "evidence": [ { "id": "FB:FBgn0034605", "url": "https://alliancegenome.org/gene/FB:FBgn0034605#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-23", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-23#orthology", "database": "AGR" }, { "id": "RGD:1564365", "url": "https://alliancegenome.org/gene/RGD:1564365#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABK0L4Q8-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "LOC134478834", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFKMPRKWISALFLLQISYCFKSGHCGKVLVWPMDFSHWMNIKIILDELVQRGHEVTVLKPSAYFFLDPKKSSDLKFEIFPTSISKDELQNHFIKLLDVWTYELPRDTCLSYSPILQNLVYEFSYFYLSICKDAVSNKQLMTKLQESKFDVLFADPVASCGDLIAELLHIPFLYSLSFSPGHKLEKSIGKFILPPSYVPVILSGLAGKMTFIDRVKNMICMLYFDFWFERLRHKEWDTFYSEILGRPTTVDETMSKVEIWLIRSYWDLKFPHPTLPNVDYIGGLHCKPAKPLPKDMEEFVQSSGEHGVVVFSLGSMVSNMTEEKANAIAWALAQIPQKVLWKFDGKTPATLGPNTRVYKWLPQNDILGHPKTKAFVTHGGANGLYEAIYHGIPMIGIPLFGDQPDNIAHMVAKGAAVSLNIRTMSKLDFLSALEEVIDNPFYKKNVMLLSTIHHDQPMKPLDRAVFWIEFIMRHKGAKHLRPLGHNLPWYQYHSLDVIGFLLTCFAVIAALTVKCLLFMYRFFVKKEKKMKNE", "length": 533 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080721-20", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080721-20#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060929-796", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-796#orthology", "database": "AGR" }, { "id": "HGNC:12545", "url": "https://alliancegenome.org/gene/HGNC:12545#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LGK3-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt2b37", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPGKWIFALLLLQISFCLRSAKCGKVLVWPMEFSHWMNIKTILDELVQRGHEVTVLKPSAYYVLDPKKSPDLKFETFPTSVSKDELEKYFIKLVDAWTYELQRDTCLSFSPLLQNMMDEFSDYYLSVCKDAVSNKQLMAKLQESKFDVLLSDPVAACGELIAEVLHIPFLYSLRASPGHKIEKSSGRFILPPSYVPVILSGLGGQMTFIDRVKNMICMLYFDFWFHMFNAKNWDPFYTEILGRPTTLAETMGKAEMWLIRSYWDLEFPHPTLPNVDYIGGLQCKPAKPLPKDIEDFVQSSGEHGVVVFSLGSMVSSMTEEKANAVAWALAQIPQKVLWKFDGKIPATLGPNTRVYKWLPQNDLLGHPKTKAFVTHGGANGVYEAIYHGIPMIGIPMFGEQHDNIAHMVAKGAAVTLNIRTMSKSDLFNALKEVINNPFYKKNAMWLSTIHHDQPMKPLDKAIFWIEYVMRHKRAKHLRPLGHNLPWYQYHSLDVIGFLLACLAVIAALAVKCFLFIYRFFAKKQKKMKNE", "length": 530 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080721-20", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080721-20#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060929-796", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-796#orthology", "database": "AGR" }, { "id": "HGNC:12545", "url": "https://alliancegenome.org/gene/HGNC:12545#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B8JMA2-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "ugt2a5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTSGALLVCLLLCGVDVGWSGRVLVMPGEYSHWHNMRPVIEALVDKNHSVTVLVGSSSPTVPHTQKERFEYHVFKVNMEKEEADAAMRDMIHLFTNDTAAKYEGEFVMWKVMSKFVEFGDVYFRGLFDVGLLKTLRDSNYDVLFSDPMMPFSDLMAQKLNIPQVISMRATFAYAAERLCGQMPAPPSYVPAVALTDHLTDRMSFMERVENMLLYIVHSIAFPLVATFTFDGYYSEILGKPTTMCETMGKVDICLIRTYWDFEYPRPFPPNFKFVGGLHCKPAKPLSKELEEFVQSSGDHGVVVFSLGSMIKNLTSERANTIAAALGQIPQKVVWRYSGKTPETLAPNTKIYDWIPQNDLLGHPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFGDQPDNLLHIKTKGAAVVLDIHTMGSKDLVDALKAVVNNPSYKESIMRLSRIHHDQPMKPLDQAVYWIEFVMRNKGAKHLRVQAHELSWYQYHCLDVAAFLLSITALITFLWVKACCFLFRRCVRKTRPERKRQKNKKE", "length": 532 }, "evidence": [ { "id": "FB:FBgn0034605", "url": "https://alliancegenome.org/gene/FB:FBgn0034605#orthology", "database": "AGR" }, { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060929-796", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-796#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" }, { "id": "RGD:708541", "url": "https://alliancegenome.org/gene/RGD:708541#orthology", "database": "AGR" }, { "id": "RGD:628623", "url": "https://alliancegenome.org/gene/RGD:628623#orthology", "database": "AGR" }, { "id": "RGD:620895", "url": "https://alliancegenome.org/gene/RGD:620895#orthology", "database": "AGR" }, { "id": "HGNC:28183", "url": "https://alliancegenome.org/gene/HGNC:28183#orthology", "database": "AGR" }, { "id": "HGNC:12545", "url": "https://alliancegenome.org/gene/HGNC:12545#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3Z748-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt1a8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPAVFPASLPLRVCLLLAFGLAQAGRLLVVPMDGSHWFSMKMIVEKLSHRGHEVVVVIPEVSWHLGKSQNFTVKTYSVSYTLEDLSHHFNFFAHKQWENREVGMFSLLKHSGKGFFQVLFSHCRSLFNDKKLVEYLKQRSFDAVFLDPFDVCGLTIAKYFSLPSVVFSGGIFCHYLDEGAQCPSPPSYVPRILSKFADTMTFKERVWNYFSYMKERAFCPYFFKTAIEIASEVLQTPVTMTDLFSSVSIWMFRTDFVLEFPRPVMPNMVYIGGINCHPGKPLSKEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVFKCCAYGCRKCFGGKGRVKKSHKSKTH", "length": 530 }, "evidence": [ { "id": "FB:FBgn0034605", "url": "https://alliancegenome.org/gene/FB:FBgn0034605#orthology", "database": "AGR" }, { "id": "MGI:3576090", "url": "https://alliancegenome.org/gene/MGI:3576090#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E7EZQ8-1", "protein_name": "UDP glucuronosyltransferase 5 family, polypeptide B2 precursor", "gene_name": "ugt5b2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNGQWFQVIWPITLTLLLPSVPVAQCGKVLVFPVDGSHWVNMNILVEALSAKGHDVTVMRTASSCYIKEFSPHYTSINLKSKGGYNKEVLEQFASRIMHILRDGSTWGHLKLQADMWQSFLKIFEAEREMIVNMIEDQQLMQSLKDAKYDLILTDPNMFGGVILGHYLKLPMVYNVRWAGYNEAHFSIAPSPLSYVPMPSLELSDRMSFLQRVYNVVMYIFIEIGAALVISPINDALAERFIGPGTSFLSLVQGADLWLHRVDFVFEYPRPTMPNVIYMAGFQCKPSKPLPQDLEDFVQSSGDHGVIIMSLGTLIDKLPDDVAEAIAEAFAELPQKIIWRYKGKRPSALGNNTLIMDWMPQNDLLGHPKTRAFVAHGGTNGIQEAIYHGVPIIGFGLIFDQPDNLSKMRVRGAAKNVDFATMNKESFLTTVKEVLYDPSYRENMQRLSRLHKDVPVKPLDNAIFWIEFVMRHKGAAHLRTESYKMPWYSYHSVDVILVLISAVSLIILSIYAVIRYFCCRICMRKTKIKHE", "length": 531 }, "evidence": [ { "id": "FB:FBgn0034605", "url": "https://alliancegenome.org/gene/FB:FBgn0034605#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100406-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100406-3#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1LTB8-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt2b34l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVKMTAALLLLHLTIFFGSGSGGKVLVWPVEFSHWLNLKIILSELVKKGHEVVVLKPSVSFSYEVDKTSAIEFESFPSSYSIADVEVIFMDCVNESIYELPKQSFWGYFLMLQKLFERTSDYSERLCRDAAFNKELMTKLQNSGFDVILADPFTPCGDLLAEILKIPLVYSLRFFPGSTYEKYSGGLPMPPSYVPIAMSELSDRMTFVERVKHMIYVLCFDFWFQVFDEKKWNELYTEVLGRPTTLSETMAKADIWLIRTYWDLEFPHPVLPNFDFVGGLHCRPAKPLPKEIEDFVQSSGEHGVVVFSLGSMVGSLTEERANVIAAGLAQIPQKVLWRFEGKKPETLGSNTRLYKWIPQNDLLGHPKTRAFITHGGTNGIYEAIYHGIPVVGIPLFGDQKDNIVHLKTKGAAVRLDFLTMSSTDLLTALRTVTNDPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAGHDLSWVQYHSLDVIGFLLACVVTVMFILKKCCLFCCQKFTKAGRKKKKE", "length": 530 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080721-20", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080721-20#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060929-796", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-796#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "K9J7B2-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt1a6b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MACLLPAAQTLPAGFLFLVLWASVLGDKLLVVPQDGSHWLSMKEIVEHLSERGHDIVVLVPEVNLLLGESKYYRRKIFSVPYSLEELQTRFRTFGRNQFVPGAPLMGPLREYRNSMLTLEMFFSNCQSLLKDSATLSFLRENKFDALFTDPAMPCGVILAEYLNLPSVYLFRGFPCSLEHMLGQSPSPVSYVPRFYTKFSDHMTFPQRLANFIVNILENYLYYCLYSKYEIIVTDLLKRDVSLPSLHQNSLWLLRYDFVFEYPRPIMPNMIFIGGINCKKKGKLTQEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVFKCCAYGCRKCFGGKGRVKKSHKSKTH", "length": 531 }, "evidence": [ { "id": "FB:FBgn0034605", "url": "https://alliancegenome.org/gene/FB:FBgn0034605#orthology", "database": "AGR" }, { "id": "MGI:3580629", "url": "https://alliancegenome.org/gene/MGI:3580629#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O60656-1", "protein_name": "UDP-glucuronosyltransferase 1A9", "gene_name": "UGT1A9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MACTGWTSPLPLCVCLLLTCGFAEAGKLLVVPMDGSHWFTMRSVVEKLILRGHEVVVVMPEVSWQLGRSLNCTVKTYSTSYTLEDLDREFKAFAHAQWKAQVRSIYSLLMGSYNDIFDLFFSNCRSLFKDKKLVEYLKESSFDAVFLDPFDNCGLIVAKYFSLPSVVFARGILCHYLEEGAQCPAPLSYVPRILLGFSDAMTFKERVRNHIMHLEEHLLCHRFFKNALEIASEILQTPVTEYDLYSHTSIWLLRTDFVLDYPKPVMPNMIFIGGINCHQGKPLPMEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH", "length": 530 }, "evidence": [ { "id": "MGI:3576090", "url": "https://alliancegenome.org/gene/MGI:3576090#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O75310-1", "protein_name": "UDP-glucuronosyltransferase 2B11", "gene_name": "UGT2B11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTLKWTSVLLLIHLSCYFSSGSCGKVLVWAAEYSHWMNMKTILKELVQRGHEVTVLASSASILFDPNDASTLKFEVYPTSLTKTEFENIIMQQVKRWSDIRKDSFWLYFSQEQEILWELYDIFRNFCKDVVSNKKVMKKLQESRFDIVFADAVFPCGELLAALLNIRFVYSLRFTPGYTIERHSGGLIFPPSYIPIVMSKLSDQMTFMERVKNMIYVLYFDFWFQMSDMKKWDQFYSEVLGRPTTLFETMGKADIWLMRNSWSFQFPHPFLPNVDFVGGFHCKPAKPLPKEMEEFVQSSGENGVVVFSLGSVISNMTAERANVIATALAKIPQKVLWRFDGNKPDALGLNTRLYKWIPQNDLLGHPKTRAFITHGGANGIYEAIYHGIPMVGIPLFFDQPDNIAHMKAKGAAVRLDFNTMSSTDLLNALKTVINDPLYKENIMKLSRIQHDQPVKPLDRAVFWIEFVMPHKGAKHLRVAAHDLTWFQYHSLDVIGFLLACVATVIFIITKFCLFCFWKFARKGKKGKRD", "length": 529 }, "evidence": [ { "id": "FB:FBgn0034605", "url": "https://alliancegenome.org/gene/FB:FBgn0034605#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080721-20", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080721-20#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060929-796", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-796#orthology", "database": "AGR" }, { "id": "RGD:708541", "url": "https://alliancegenome.org/gene/RGD:708541#orthology", "database": "AGR" }, { "id": "RGD:628623", "url": "https://alliancegenome.org/gene/RGD:628623#orthology", "database": "AGR" }, { "id": "RGD:620895", "url": "https://alliancegenome.org/gene/RGD:620895#orthology", "database": "AGR" }, { "id": "HGNC:12545", "url": "https://alliancegenome.org/gene/HGNC:12545#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O75795-1", "protein_name": "UDP-glucuronosyltransferase 2B17", "gene_name": "UGT2B17", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLKWMSVFLLMQLSCYFSSGSCGKVLVWPTEYSHWINMKTILEELVQRGHEVIVLTSSASILVNASKSSAIKLEVYPTSLTKNDLEDFFMKMFDRWTYSISKNTFWSYFSQLQELCWEYSDYNIKLCEDAVLNKKLMRKLQESKFDVLLADAVNPCGELLAELLNIPFLYSLRFSVGYTVEKNGGGFLFPPSYVPVVMSELSDQMIFMERIKNMIYMLYFDFWFQAYDLKKWDQFYSEVLGRPTTLFETMGKAEMWLIRTYWDFEFPRPFLPNVDFVGGLHCKPAKPLPKEMEEFVQSSGENGIVVFSLGSMISNMSEESANMIASALAQIPQKVLWRFDGKKPNTLGSNTRLYKWLPQNDLLGHPKTKAFITHGGTNGIYEAIYHGIPMVGIPLFADQHDNIAHMKAKGAALSVDIRTMSSRDLLNALKSVINDPIYKENIMKLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHNLTWIQYHSLDVIAFLLACVATMIFMITKCCLFCFRKLAKTGKKKKRD", "length": 530 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080721-20", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080721-20#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060929-796", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-796#orthology", "database": "AGR" }, { "id": "RGD:708541", "url": "https://alliancegenome.org/gene/RGD:708541#orthology", "database": "AGR" }, { "id": "RGD:628623", "url": "https://alliancegenome.org/gene/RGD:628623#orthology", "database": "AGR" }, { "id": "RGD:620895", "url": "https://alliancegenome.org/gene/RGD:620895#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P06133-1", "protein_name": "UDP-glucuronosyltransferase 2B4", "gene_name": "UGT2B4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSMKWTSALLLIQLSCYFSSGSCGKVLVWPTEFSHWMNIKTILDELVQRGHEVTVLASSASISFDPNSPSTLKFEVYPVSLTKTEFEDIIKQLVKRWAELPKDTFWSYFSQVQEIMWTFNDILRKFCKDIVSNKKLMKKLQESRFDVVLADAVFPFGELLAELLKIPFVYSLRFSPGYAIEKHSGGLLFPPSYVPVVMSELSDQMTFIERVKNMIYVLYFEFWFQIFDMKKWDQFYSEVLGRPTTLSETMAKADIWLIRNYWDFQFPHPLLPNVEFVGGLHCKPAKPLPKEMEEFVQSSGENGVVVFSLGSMVSNTSEERANVIASALAKIPQKVLWRFDGNKPDTLGLNTRLYKWIPQNDLLGHPKTRAFITHGGANGIYEAIYHGIPMVGVPLFADQPDNIAHMKAKGAAVSLDFHTMSSTDLLNALKTVINDPLYKENAMKLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLTWFQYHSLDVTGFLLACVATVIFIITKCLFCVWKFVRTGKKGKRD", "length": 528 }, "evidence": [ { "id": "FB:FBgn0034605", "url": "https://alliancegenome.org/gene/FB:FBgn0034605#orthology", "database": "AGR" }, { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080721-20", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080721-20#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060929-796", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-796#orthology", "database": "AGR" }, { "id": "RGD:708541", "url": "https://alliancegenome.org/gene/RGD:708541#orthology", "database": "AGR" }, { "id": "RGD:628623", "url": "https://alliancegenome.org/gene/RGD:628623#orthology", "database": "AGR" }, { "id": "RGD:620895", "url": "https://alliancegenome.org/gene/RGD:620895#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P08430-1", "protein_name": "UDP-glucuronosyltransferase 1A6", "gene_name": "Ugt1a6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MACLLPAARLPAGFLFLVLWGSVLGDKLLVVPQDGSHWLSMKEIVEHLSERGHDIVVLVPEVNLLLGESKYYRRKSFPVPYNLEELRTRYRSFGNNHFAASSPLMAPLREYRNNMIVIDMCFFSCQSLLKDSATLSFLRENQFDALFTDPAMPCGVILAEYLKLPSIYLFRGFPCSLEHIGQSPSPVSYVPRFYTKFSDHMTFPQRLANFIANILENYLYHCLYSKYEILASDLLKRDVSLPALHQNSLWLLRYDFVFEYPRPVMPNMIFIGGTNCKKKGNLSQEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTLLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKARAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVYKSCAYGCRKCFGGKGRVKKSHKSKTH", "length": 529 }, "evidence": [ { "id": "SGD:S000004179", "url": "https://alliancegenome.org/gene/SGD:S000004179#orthology", "database": "AGR" }, { "id": "MGI:2137698", "url": "https://alliancegenome.org/gene/MGI:2137698#orthology", "database": "AGR" }, { "id": "MGI:3580629", "url": "https://alliancegenome.org/gene/MGI:3580629#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P08542-1", "protein_name": "UDP-glucuronosyltransferase 2B17", "gene_name": "Ugt2b17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPGKWISALLLLQISCCFQSGNCGKVLVWPMEFSHWMNIKTILDELVQRGHEVTVLKPSAYYVLDPKKSPDLKFETFPTSVSKDELENYFIKLVDVWTYELQRDTCLSYSPLLQNMIDGFSDYYLSLCKDTVSNKQLMAKLQESKFDVLLSDPVAACGELIAEVLHIPFLYSLRFSPGYKIEKSSGRFILPPSYVPVILSGMGGPMTFIDRVKNMICTLYFDFWFHMFNAKKWDPFYSEILGRPTTLAETMGKAEMWLIRSYWDLEFPHPTLPNVDYIGGLQCRPPKPLPKDMEDFVQSSGEHGVVVFSLGSMVSSMTEEKANAIAWALAQIPQKVLWKFDGKTPATLGPNTRVYKWLPQNDLLGHPKTKAFVTHSGANGVYEAIYHGIPMVGIPMFGEQHDNIAHMVAKGAAVTLNIRTMSKSDLFNALKEIINNPFYKKNAVWLSTIHHDQPMKPLDKAVFWIEFVMRHKGAKHLRPLGHDLPWYQYHSLDVIGFLLTCSAVIAVLTVKCFLFIYRLFVKKEKKMKNE", "length": 530 }, "evidence": [ { "id": "FB:FBgn0034605", "url": "https://alliancegenome.org/gene/FB:FBgn0034605#orthology", "database": "AGR" }, { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080721-20", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080721-20#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060929-796", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-796#orthology", "database": "AGR" }, { "id": "RGD:628623", "url": "https://alliancegenome.org/gene/RGD:628623#orthology", "database": "AGR" }, { "id": "HGNC:12545", "url": "https://alliancegenome.org/gene/HGNC:12545#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P09875-1", "protein_name": "UDP-glucuronosyltransferase 2B1", "gene_name": "Ugt2b1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSMKQTSVFLLIQLICYFRPGACGKVLVWPTEYSHWINIKIILNELAQRGHEVTVLVSSASILIEPTKESSINFEIYSVPLSKSDLEYSFAKWIDEWTRDFETLSIWTYYSKMQKVFNEYSDVVENLCKALIWNKSLMKKLQGSQFDVILADAVGPCGELLAELLKTPLVYSLRFCPGYRCEKFSGGLPLPPSYVPVVLSELSDRMTFVERVKNMLQMLYFDFWFQPFKEKSWSQFYSDVLGRPTTLTEMMGKADIWLIRTFWDLEFPHPFLPNFDFVGGLHCKPAKPLPREMEEFVQSSGEHGVVVFSLGSMVKNLTEEKANVVASALAQIPQKVVWRFDGKKPDTLGSNTRLYKWIPQNDLLGHPKTKAFVAHGGTNGIYEAIYHGIPIVGIPLFADQPDNINHMVAKGAAVRVDFSILSTTGLLTALKIVMNDPSYKENAMRLSRIHHDQPVKPLDRAVFWIEYVMRHKGAKHLRSTLHDLSWFQYHSLDVIGFLLLCVVGVVFIITKFCLFCCRKTANMGKKKKE", "length": 529 }, "evidence": [ { "id": "FB:FBgn0034605", "url": "https://alliancegenome.org/gene/FB:FBgn0034605#orthology", "database": "AGR" }, { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080721-20", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080721-20#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060929-796", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-796#orthology", "database": "AGR" }, { "id": "RGD:708541", "url": "https://alliancegenome.org/gene/RGD:708541#orthology", "database": "AGR" }, { "id": "HGNC:12545", "url": "https://alliancegenome.org/gene/HGNC:12545#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0DTE4-5", "protein_name": "UDP-glucuronosyltransferase 2A1", "gene_name": "UGT2A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLNNLLLFSLQISLIGTTLGGNVLIWPMEGSHWLNVKIIIDELIKKEHNVTVLVASGALFITPTSNPSLTFEIYKVPFGKERIEGVIKDFVLTWLENRPSPSTIWRFYQEMAKVIKDFHMVSQEICDGVLKNQQLMAKLKKSKFEVLVSDPVFPCGDIVALKLGIPFMYSLRFSPASTVEKHCGKVPYPPSYVPAVLSELTDQMSFTDRIRNFISYHLQDYMFETLWKSWDSYYSKALGGLLLCCPGWSAVADLGSLQPLLPGFKRFSRLSLHCSWDYRLPAGRPTTLCETMGKAEIWLIRTYWDFEFPRPYLPNFEFVGGLHCKPAKPLPKVLWRYKGKKPATLGNNTQLFDWIPQNDLLGHPKTKAFITHGGTNGIYEAIYHGVPMVGVPMFADQPDNIAHMKAKGAAVEVNLNTMTSVDLLSALRTVINEPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLTWFQYHSLDVIGFLLVCVTTAIFLVIQCCLFSCQKFGKIGKKKKRE", "length": 527 }, "evidence": [ { "id": "FB:FBgn0034605", "url": "https://alliancegenome.org/gene/FB:FBgn0034605#orthology", "database": "AGR" }, { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080721-20", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080721-20#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060929-796", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-796#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DTE5-1", "protein_name": "UDP-glucuronosyltransferase 2A2", "gene_name": "UGT2A2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVSIRDFTMPKKFVQMLVFNLTLTEVVLSGNVLIWPTDGSHWLNIKIILEELIQRNHNVTVLASSATLFINSNPDSPVNFEVIPVSYKKSNIDSLIEHMIMLWIDHRPTPLTIWAFYKELGKLLDTFFQINIQLCDGVLKNPKLMARLQKGGFDVLVADPVTICGDLVALKLGIPFMYTLRFSPASTVERHCGKIPAPVSYVPAALSELTDQMTFGERIKNTISYSLQDYIFQSYWGEWNSYYSKILGRPTTLCETMGKAEIWLIRTYWDFEFPRPYLPNFEFVGGLHCKPAKPLPKEMEEFIQSSGKNGVVVFSLGSMVKNLTEEKANLIASALAQIPQKVLWRYKGKKPATLGNNTQLFDWIPQNDLLGHPKTKAFITHGGTNGIYEAIYHGVPMVGVPMFADQPDNIAHMKAKGAAVEVNLNTMTSVDLLSALRTVINEPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLTWFQYHSLDVIGFLLVCVTTAIFLVIQCCLFSCQKFGKIGKKKKRE", "length": 536 }, "evidence": [ { "id": "FB:FBgn0034605", "url": "https://alliancegenome.org/gene/FB:FBgn0034605#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080721-20", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080721-20#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060929-796", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-796#orthology", "database": "AGR" }, { "id": "HGNC:28183", "url": "https://alliancegenome.org/gene/HGNC:28183#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P16662-1", "protein_name": "UDP-glucuronosyltransferase 2B7", "gene_name": "UGT2B7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSVKWTSVILLIQLSFCFSSGNCGKVLVWAAEYSHWMNIKTILDELIQRGHEVTVLASSASILFDPNNSSALKIEIYPTSLTKTELENFIMQQIKRWSDLPKDTFWLYFSQVQEIMSIFGDITRKFCKDVVSNKKFMKKVQESRFDVIFADAIFPCSELLAELFNIPFVYSLSFSPGYTFEKHSGGFIFPPSYVPVVMSELTDQMTFMERVKNMIYVLYFDFWFEIFDMKKWDQFYSEVLGRPTTLSETMGKADVWLIRNSWNFQFPYPLLPNVDFVGGLHCKPAKPLPKEMEDFVQSSGENGVVVFSLGSMVSNMTEERANVIASALAQIPQKVLWRFDGNKPDTLGLNTRLYKWIPQNDLLGHPKTRAFITHGGANGIYEAIYHGIPMVGIPLFADQPDNIAHMKARGAAVRVDFNTMSSTDLLNALKRVINDPSYKENVMKLSRIQHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLTWFQYHSLDVIGFLLVCVATVIFIVTKCCLFCFWKFARKAKKGKND", "length": 529 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080721-20", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080721-20#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060929-796", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-796#orthology", "database": "AGR" }, { "id": "RGD:708541", "url": "https://alliancegenome.org/gene/RGD:708541#orthology", "database": "AGR" }, { "id": "RGD:628623", "url": "https://alliancegenome.org/gene/RGD:628623#orthology", "database": "AGR" }, { "id": "RGD:620895", "url": "https://alliancegenome.org/gene/RGD:620895#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P17717-1", "protein_name": "UDP-glucuronosyltransferase 2B17", "gene_name": "Ugt2b17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPGKWISALLLLQISCCFRSVKCGKVLVWPMEFSHWMNIKIILDELVQRGHEVTVLRPSAYYVLDPKKSPGLKFETFPTSVSKDNLENFFIKFVDVWTYEMPRDTCLSYSPLLQNMIDEFSDYFLSLCKDVVSNKELMTKLQESKFDVLLSDPVASCGELIAELLQIPFLYSIRFSPGYQIEKSSGRFLLPPSYVPVILSGLGGQMTFIERIKNMICMLYFDFWFQMFNDKKWDSFYSEYLGRPTTLVETMGQAEMWLIRSNWDLEFPHPTLPNVDYVGGLHCKPAKPLPKDMEEFVQSSGDHGVVVFSLGSMVSNMTEEKANAIAWALAQIPQKVLWKFDGKTPATLGHNTRVYKWLPQNDLLGHPKTKAFVTHGGANGVYEAIYHGIPMIGIPLFGEQHDNIAHMVAKGAAVALNIRTMSKSDVLNALEEVIENPFYKKNAIWLSTIHHDQPMKPLDRAVFWIEFVMRHKRAKHLRPLGHNLTWYQYHSLDVIGFLLSCVATTIVLSVKCLLFIYRFFVKKENKMKNE", "length": 530 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080721-20", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080721-20#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060929-796", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-796#orthology", "database": "AGR" }, { "id": "RGD:628623", "url": "https://alliancegenome.org/gene/RGD:628623#orthology", "database": "AGR" }, { "id": "HGNC:12545", "url": "https://alliancegenome.org/gene/HGNC:12545#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P19224-1", "protein_name": "UDP-glucuronosyltransferase 1A6", "gene_name": "UGT1A6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MACLLRSFQRISAGVFFLALWGMVVGDKLLVVPQDGSHWLSMKDIVEVLSDRGHEIVVVVPEVNLLLKESKYYTRKIYPVPYDQEELKNRYQSFGNNHFAERSFLTAPQTEYRNNMIVIGLYFINCQSLLQDRDTLNFFKESKFDALFTDPALPCGVILAEYLGLPSVYLFRGFPCSLEHTFSRSPDPVSYIPRCYTKFSDHMTFSQRVANFLVNLLEPYLFYCLFSKYEELASAVLKRDVDIITLYQKVSVWLLRYDFVLEYPRPVMPNMVFIGGINCKKRKDLSQEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH", "length": 532 }, "evidence": [ { "id": "MGI:2137698", "url": "https://alliancegenome.org/gene/MGI:2137698#orthology", "database": "AGR" }, { "id": "MGI:3580629", "url": "https://alliancegenome.org/gene/MGI:3580629#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P36510-1", "protein_name": "UDP-glucuronosyltransferase 2A1", "gene_name": "Ugt2a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLKNILLWSLQLSLLGMSLGGNVLIWPMEGSHWLNVKIIIDELLRKEHNVTVLVASGALFITPSVSPSLTFEIYPVPFGKEKIESVIKDFVLTWLENRPSPSTIWTFYKEMAKVIEEFHLVSRGICDGVLKNEKLMTKLQRGKFEVLLSDPVFPCGDIVALKLGIPFIYSLRFSPASTVEKHCGKVPFPPSYVPAILSELTDQMSFADRVRNFISYRMQDYMFETLWKQWDSYYSKALGRPTTLCETMGKAEIWLMRTYWDFEFPRPYLPNFEFVGGLHCKPAKPLPKEMEEFVQTSGEHGVVVFSLGSMVKNLTEEKANLIASALAQIPQKVLWRYKGKIPATLGSNTRLFDWIPQNDLLGHPKTRAFITHGGTNGIYEAIYHGIPMVGVPMFADQPDNIAHMKAKGAAVEVNMNTMTSADLLSAVRAVINEPFYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSLDVIGFLLACMASAILLVIKCCLFVFQKIGKTXKKNKRD", "length": 527 }, "evidence": [ { "id": "FB:FBgn0034605", "url": "https://alliancegenome.org/gene/FB:FBgn0034605#orthology", "database": "AGR" }, { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080721-20", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080721-20#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060929-796", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-796#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P36511-1", "protein_name": "UDP-glucuronosyltransferase 2B15", "gene_name": "Ugt2b15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGKWISALLLLQISFCFKSGNCGKVLVWPMEYSHWMNIKIILEELVQKGHEVTVLRPSAFVFLDPKETSDLKFVTFPTSFSSHDLENFFTRFVNVWTYELPRDTCLSYFLYLQDTIDEYSDYCLTVCKEAVSNKQFMTKLQESKFDVVFSDAIGPCGELIAELLQIPFLYSLRFSPGYTIEQYIGGVLFPPSYVPMIFSGLAGQMTFIERVHNMICMLYFDFWFQTFREKKWDPFYSKTLGRPTTLAEIMGKAEMWLIRSYWDLEFPHPISPNVDYIGGLHCKPAKPLPKDIEDFVQSSGEHGVVVFSLGSMVRNMTEEKANIIAWALAQIPQKVLWRFDGKKPPTLGPNTRLYKWLPQNDLLGHPKTKAFVTHGGANGIYEAIHHGIPMIGIPLFAEQHDNIAHMVAKGAAVEVNFRTMSKSDLLNALEEVIDNPFYKKNAMWLSTIHHDQPTKPLDRAVFWIEFVMRHKGAKHLRSLGHNLPWYQYHSLDVIGFLLSCVAVTVVLALKCFLFVYRFFVKKEKKTKNE", "length": 530 }, "evidence": [ { "id": "FB:FBgn0034605", "url": "https://alliancegenome.org/gene/FB:FBgn0034605#orthology", "database": "AGR" }, { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080721-20", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080721-20#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060929-796", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-796#orthology", "database": "AGR" }, { "id": "RGD:620895", "url": "https://alliancegenome.org/gene/RGD:620895#orthology", "database": "AGR" }, { "id": "HGNC:12545", "url": "https://alliancegenome.org/gene/HGNC:12545#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P36537-1", "protein_name": "UDP-glucuronosyltransferase 2B10", "gene_name": "UGT2B10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALKWTTVLLIQLSFYFSSGSCGKVLVWAAEYSLWMNMKTILKELVQRGHEVTVLASSASILFDPNDSSTLKLEVYPTSLTKTEFENIIMQLVKRLSEIQKDTFWLPFSQEQEILWAINDIIRNFCKDVVSNKKLMKKLQESRFDIVFADAYLPCGELLAELFNIPFVYSHSFSPGYSFERHSGGFIFPPSYVPVVMSKLSDQMTFMERVKNMLYVLYFDFWFQIFNMKKWDQFYSEVLGRPTTLSETMRKADIWLMRNSWNFKFPHPFLPNVDFVGGLHCKPAKPLPKEMEEFVQSSGENGVVVFSLGSMVSNMTEERANVIATALAKIPQKVLWRFDGNKPDALGLNTRLYKWIPQNDLLGHPKTRAFITHGGANGIYEAIYHGIPMVGIPLFFDQPDNIAHMKAKGAAVRVDFNTMSSTDLLNALKTVINDPSYKENIMKLSRIQHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHNLTWFQYHSLDVIGFLLACVATVLFIITKCCLFCFWKFARKGKKGKRD", "length": 528 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080721-20", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080721-20#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060929-796", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-796#orthology", "database": "AGR" }, { "id": "RGD:708541", "url": "https://alliancegenome.org/gene/RGD:708541#orthology", "database": "AGR" }, { "id": "RGD:628623", "url": "https://alliancegenome.org/gene/RGD:628623#orthology", "database": "AGR" }, { "id": "RGD:620895", "url": "https://alliancegenome.org/gene/RGD:620895#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P54855-1", "protein_name": "UDP-glucuronosyltransferase 2B15", "gene_name": "UGT2B15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLKWTSVFLLIQLSCYFSSGSCGKVLVWPTEYSHWINMKTILEELVQRGHEVTVLTSSASTLVNASKSSAIKLEVYPTSLTKNYLEDSLLKILDRWIYGVSKNTFWSYFSQLQELCWEYYDYSNKLCKDAVLNKKLMMKLQESKFDVILADALNPCGELLAELFNIPFLYSLRFSVGYTFEKNGGGFLFPPSYVPVVMSELSDQMIFMERIKNMIHMLYFDFWFQIYDLKKWDQFYSEVLGRPTTLFETMGKAEMWLIRTYWDFEFPRPFLPNVDFVGGLHCKPAKPLPKEMEEFVQSSGENGIVVFSLGSMISNMSEESANMIASALAQIPQKVLWRFDGKKPNTLGSNTRLYKWLPQNDLLGHPKTKAFITHGGTNGIYEAIYHGIPMVGIPLFADQHDNIAHMKAKGAALSVDIRTMSSRDLLNALKSVINDPVYKENVMKLSRIHHDQPMKPLDRAVFWIEFVMRHKGAKHLRVAAHNLTWIQYHSLDVIAFLLACVATVIFIITKFCLFCFRKLAKKGKKKKRD", "length": 530 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080721-20", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080721-20#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060929-796", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-796#orthology", "database": "AGR" }, { "id": "RGD:708541", "url": "https://alliancegenome.org/gene/RGD:708541#orthology", "database": "AGR" }, { "id": "RGD:628623", "url": "https://alliancegenome.org/gene/RGD:628623#orthology", "database": "AGR" }, { "id": "RGD:620895", "url": "https://alliancegenome.org/gene/RGD:620895#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q06321-1", "protein_name": "Sterol 3-beta-glucosyltransferase", "gene_name": "ATG26", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MPITQIISASDSEAGPKPSISLVPDKPSEPETSPRHHRLSRSLSKFKRWRGRSNSSLSMGSSEQQELQDSPNEARSDDDENGYNNDNADDLAKSKYMMKSIAGLLTTASVYAGMNNAQEMNVLSQVDSEESDSSDSFQENIGRNEVKSKKENLKTKSHPEVPRLDKRKPTLFDFSITREKLSKDNVAKLRQRFCLDEQEPFLNDFPAWLLKDVLVQGHIFITTKHFLFFAYLPKNPRSVKMSGNLNIRTKLIRSTRYWCVLKNHLFSMYTSSTELYFPVLTIDLREVQKIETQKHTLNGSATKTFKLYTDESTFKFNADSEFSAKSWVNALKKEQFAAQNSENNSISLKIPLPNIIEIDDQPIVNKALTLRLRALESSQTYAIDDFMFVFMDGSGSQVKESLGEQLAILQKSGVNTLYYDIPAKKSKSSFGKETPATVEQKNNGEDSKYLNVPTSAVPSSENGKKSRFRFRERSNSWFRRAKPLEDSQVEDVEEIYKDAANDIDSSVHSTIHIHEQEDSQEQTVAWKPSHLKNFAEMWAAKPIHYRNKFIPFQKDDTYLIKETEEVSANERFRYHFKFNKEKSLISTYYTYLNRNVPVYGKIYVSNDTVCFRSLLPGSNTYMVLPLVDVETCYKEKGFRFGYFVLVIVIHGHEELFFEFSTEVARDDIERILLKLLDNIYASSAEGSNISSASLGDVQHNPDSAKLKLFEDKINAEGFEVPLMIDENPHYKTSIKPNKSYKFGLLTIGSRGDVQPYIALGKGLIKEGHQVVIITHSEFRDFVESHGIQFEEIAGNPVELMSLMVENESMNVKMLREASSKFRGWIDALLQTSWEVCNRRKFDILIESPSAMVGIHITEALQIPYFRAFTMPWTRTRAYPHAFIVPDQKRGGNYNYLTHVLFENVFWKGISGQVNKWRVETLGLGKTNLFLLQQNNVPFLYNVSPTIFPPSIDFSEWVRVTGYWFLDDKSTFKPPAELQEFISEARSKGKKLVYIGFGSIVVSNAKEMTEALVEAVMEADVYCILNKGWSERLGDKAAKKTEVDLPRNILNIGNVPHDWLFPQVDAAVHHGGSGTTGASLRAGLPTVIKPFFGDQFFYAGRVEDIGVGIALKKLNAQTLADALKVATTNKIMKDRAGLIKKKISKEDGIKTAISAIYNELEYARSVTLSRVKTPRKKEENVDATKLTPAETTDEGWTMI", "length": 1198 }, "evidence": [ { "id": "MGI:2146055", "url": "https://alliancegenome.org/gene/MGI:2146055#orthology", "database": "AGR" }, { "id": "FB:FBgn0034605", "url": "https://alliancegenome.org/gene/FB:FBgn0034605#orthology", "database": "AGR" }, { "id": "SGD:S000004179", "url": "https://alliancegenome.org/gene/SGD:S000004179#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q3SY77-1", "protein_name": "UDP-glycosyltransferase 3A2", "gene_name": "UGT3A2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGQRVLLLVGFLLPGVLLSEAAKILTISTVGGSHYLLMDRVSQILQDHGHNVTMLNHKRGPFMPDFKKEEKSYQVISWLAPEDHQREFKKSFDFFLEETLGGRGKFENLLNVLEYLALQCSHFLNRKDIMDSLKNENFDMVIVETFDYCPFLIAEKLGKPFVAILSTSFGSLEFGLPIPLSYVPVFRSLLTDHMDFWGRVKNFLMFFSFCRRQQHMQSTFDNTIKEHFTEGSRPVLSHLLLKAELWFINSDFAFDFARPLLPNTVYVGGLMEKPIKPVPQDLENFIAKFGDSGFVLVTLGSMVNTCQNPEIFKEMNNAFAHLPQGVIWKCQCSHWPKDVHLAANVKIVDWLPQSDLLAHPSIRLFVTHGGQNSIMEAIQHGVPMVGIPLFGDQPENMVRVEAKKFGVSIQLKKLKAETLALKMKQIMEDKRYKSAAVAASVILRSHPLSPTQRLVGWIDHVLQTGGATHLKPYVFQQPWHEQYLLDVFVFLLGLTLGTLWLCGKLLGMAVWWLRGARKVKET", "length": 523 }, "evidence": [ { "id": "MGI:2146055", "url": "https://alliancegenome.org/gene/MGI:2146055#orthology", "database": "AGR" }, { "id": "SGD:S000004179", "url": "https://alliancegenome.org/gene/SGD:S000004179#orthology", "database": "AGR" }, { "id": "RGD:1564365", "url": "https://alliancegenome.org/gene/RGD:1564365#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3UP75-1", "protein_name": "UDP-glycosyltransferase 3A1", "gene_name": "Ugt3a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAHRSWLLVSFFLLEVLLLEAAKILTISTLSASHYILMNRVSQILQGGGHDVIKLLYEGGDIPDFRKENSSYQVINWRLPEDQQKTFENRWHRLIDEYAYGRSKYHTLLKIHQYFADLCSHLLSRKDIMELLQKENFDLVLLDSMDLCSFLIVEKLGKRFVSFLPFQFSYMDFGLPNAPLSYAPVYGSGLTDQMDFWGRVKNILMFFHFTKKRRDIFSQYGNTVQEHFAEGSQPVLSDLLLKAELWFVNSDFALDFARPLFPNTVYVGGLLDKPVQPIPQDLEDFISQFGDSGFVLVALGSVVSMIQSKEIIKEMNSAFAHLPQGVLWTCKSSHWPKDVSLAPNVKIMDWLPQIDLLAHPSIRLFVTHGGMNSVMEAVHHGVPMVGIPFFGDQPENMVRVEAKNLGVSIQLQTLKAESFLLTMKEVIEDQRYKTAAMASKVIRQSHPLTPAQRLVGWIDHILQTGGAAHLKPYAFQQPWHEQYMLDVFLFLLGLTLGTLWLSVKVLVAVTRYLSISRKVKQA", "length": 523 }, "evidence": [ { "id": "MGI:2146055", "url": "https://alliancegenome.org/gene/MGI:2146055#orthology", "database": "AGR" }, { "id": "FB:FBgn0034605", "url": "https://alliancegenome.org/gene/FB:FBgn0034605#orthology", "database": "AGR" }, { "id": "SGD:S000004179", "url": "https://alliancegenome.org/gene/SGD:S000004179#orthology", "database": "AGR" }, { "id": "RGD:1564365", "url": "https://alliancegenome.org/gene/RGD:1564365#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q62789-1", "protein_name": "UDP-glucuronosyltransferase 2B7", "gene_name": "Ugt2b7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPQKWISALLLLQISFCFRSGNCGKVLVWPLEYSHWMNLKIILDELVQRGHEVTVLRPSSSVSLDPKKASGLVYETSPTTSNNDEVEKSFYPVGDMWTYDVPKYTCLRYYPSLNKMFGQFSDLWLQLCREVVSNKELIAKLKESQFDVVLSDAVGPCGELIAEILQLPFVYSLRFATAPGIEKYSAGQPFPPSYVPIILSGFSGQMTFMERVENMLCLLYFDSWFESFPAKDWDPFFSEILGRPTTMVDTMKKAEIWLIRSYWDLEFPRPSLPNIEFVGGLHCQPAKPLPKEMEDFAQSSGEHGVWVFSLGSMIRNITQERANTIASALAQIPQKVFWRFEGKKPDTLGPNTRVFKWIPQNDLLGHPKTKAFVTHGGANGIYESIHYGIPPMVGIPLFAEQRDNVAHMVAKGAAVSIDFHTMSSSDLLNALKAVINNPSYKKKVMWLSAIHHDQPLKPLDRAVFWIEFVMRHKGAKHLRPLAHNLALVSVHSLDVIGFLLACVLAIVLLAVKCCLFLYRFFVKVAKNKRD", "length": 530 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080721-20", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080721-20#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060929-796", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-796#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q64435-1", "protein_name": "UDP-glucuronosyltransferase 1A6", "gene_name": "Ugt1a6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MACLLPAAQTLPAGFLFLVLWASVLGDKLLVVPQDGSHWLSMKEIVEHLSERGHDIMVLVPEVNLLLGESKYYRRKIFSVTYSLEELQTRFRTFGNNHFLPGASLMGPLREYRNNMIVVDMFFSNCQSLLKDSATLSFLRENKFDALFTDPAMPCGVILAEYLNLPSVYLFRGFPCSLEHMLGQSPSPVSYVPRFYTKFSDHMTFPQRLANFIVNILENYLYYCLYSKYEIIASDLLKRDVSLPSLHQNSLWLLRYDFVFEYPRPVMPNMIFLGGINCKKKGKLTQEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVFKCCAYGCRKCFGGKGRVKKSHKSKTH", "length": 531 }, "evidence": [ { "id": "FB:FBgn0034605", "url": "https://alliancegenome.org/gene/FB:FBgn0034605#orthology", "database": "AGR" }, { "id": "MGI:2137698", "url": "https://alliancegenome.org/gene/MGI:2137698#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q64634-1", "protein_name": "UDP-glucuronosyltransferase 1A8", "gene_name": "Ugt1a8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPSGCPPSLPLCVCLFLASGFAQAGRLLVVPMDGSHWFTMQMIVEKLSHRGHEVVVVIPEVSWHMGKSLNFTVKLLLVLNTLEDLNYHFKFFAHNQWKTQEVGMFSLLKHSGKGFFELLFSHCRSLFKDKKLVEYLKQSSFDAVFLDPFDVCGLILAKYFSLPSVVFSGGIFCHYLDEGAQCPSPPSYVPRILSKFTDTMTFKERVWNHLSYMKERAFCPYFFKTAVEIASEVLQTPVTMRDLFSPVSIWMFRTDFVLEFPRPMMPNMVYIGGINCHQGKPLSKEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTLLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKARAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVYKSCAYGCRKCFGGKGRVKKSHKSKTH", "length": 530 }, "evidence": [ { "id": "MGI:3576090", "url": "https://alliancegenome.org/gene/MGI:3576090#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6NUS8-1", "protein_name": "UDP-glycosyltransferase 3A1", "gene_name": "UGT3A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVGQRVLLLVAFLLSGVLLSEAAKILTISTLGGSHYLLLDRVSQILQEHGHNVTMLHQSGKFLIPDIKEEEKSYQVIRWFSPEDHQKRIKKHFDSYIETALDGRKESEALVKLMEIFGTQCSYLLSRKDIMDSLKNENYDLVFVEAFDFCSFLIAEKLVKPFVAILPTTFGSLDFGLPSPLSYVPVFPSLLTDHMDFWGRVKNFLMFFSFSRSQWDMQSTFDNTIKEHFPEGSRPVLSHLLLKAELWFVNSDFAFDFARPLLPNTVYIGGLMEKPIKPVPQDLDNFIANFGDAGFVLVAFGSMLNTHQSQEVLKKMHNAFAHLPQGVIWTCQSSHWPRDVHLATNVKIVDWLPQSDLLAHPSIRLFVTHGGQNSVMEAIRHGVPMVGLPVNGDQHGNMVRVVAKNYGVSIRLNQVTADTLTLTMKQVIEDKRYKSAVVAASVILHSQPLSPAQRLVGWIDHILQTGGATHLKPYAFQQPWHEQYLIDVFVFLLGLTLGTMWLCGKLLGVVARWLRGARKVKKT", "length": 523 }, "evidence": [ { "id": "MGI:2146055", "url": "https://alliancegenome.org/gene/MGI:2146055#orthology", "database": "AGR" }, { "id": "RGD:1564365", "url": "https://alliancegenome.org/gene/RGD:1564365#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6PDD0-1", "protein_name": "UDP-glucuronosyltransferase 2A2", "gene_name": "Ugt2a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIKKVLQLLIFHLTLAEIVLSGNVVVWPTDGSHWLNIKILLEELVQRNHSVTVLAPSETLFINSRLDAFINFEEIPVSYTKSKIDEIIEHMIALWLDHRPTPLTMWTFYKELGNLLATFYTTNKQMCDGVLNNPTVMERLQKGGFDVLLADPVTMCGELVALKLGIPFVYTLRFSPAFTVERHCGKIPAPISYVPAALSELTDQMSFGERVKNIISYSLQDYIFKTYWGEWNSYYSKVLGRPTTLCETMGKAEIWLMRTYWDFEFPRPYLPNFEFVGGLHCKPAKPLPKEMEEFVQTSGEHGIVVFSLGSMVKNLTDEKANLIASALAQIPQKVLWRYKGKIPDTLGSNTRLFDWIPQNDLLGHPKTRAFITHGGTNGIYEAIYHGIPMVGVPMFADQPDNIAHMKAKGAAVEVNMNTMTSSDLLNALRTVINEPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSLDVIGFLLACVASAILLVAKCCLFIFQKVGKTGKKKKRD", "length": 528 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080721-20", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080721-20#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060929-796", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-796#orthology", "database": "AGR" }, { "id": "HGNC:28183", "url": "https://alliancegenome.org/gene/HGNC:28183#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6UWM9-1", "protein_name": "UDP-glucuronosyltransferase 2A3", "gene_name": "UGT2A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRSDKSALVFLLLQLFCVGCGFCGKVLVWPCDMSHWLNVKVILEELIVRGHEVTVLTHSKPSLIDYRKPSALKFEVVHMPQDRTEENEIFVDLALNVLPGLSTWQSVIKLNDFFVEIRGTLKMMCESFIYNQTLMKKLQETNYDVMLIDPVIPCGDLMAELLAVPFVLTLRISVGGNMERSCGKLPAPLSYVPVPMTGLTDRMTFLERVKNSMLSVLFHFWIQDYDYHFWEEFYSKALGRPTTLCETVGKAEIWLIRTYWDFEFPQPYQPNFEFVGGLHCKPAKALPKEMENFVQSSGEDGIVVFSLGSLFQNVTEEKANIIASALAQIPQKVLWRYKGKKPSTLGANTRLYDWIPQNDLLGHPKTKAFITHGGMNGIYEAIYHGVPMVGVPIFGDQLDNIAHMKAKGAAVEINFKTMTSEDLLRALRTVITDSSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRSAAHDLTWFQHYSIDVIGFLLACVATAIFLFTKCFLFSCQKFNKTRKIEKRE", "length": 527 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080721-20", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080721-20#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060929-796", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-796#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80X89-1", "protein_name": "UDP-glucuronosyltransferase 2A1", "gene_name": "Ugt2a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLKNILLCSLQISLLGMSLGGNVLIWPMEGSHWLNVKIIIDELLRKEHNVTVLVASGALFITPSSISPSLTFEIYPVPFGKEKIESVIKDFVLTWLENRPSPSTIWTFYKEMAKVIEEFHLVSRGICDGVLKNEKLMSKLQKEKFEVLLSDPVFPCGDIVALKLGIPFIYSLRFSPASTVEKHCGKVPFPPSYVPAILSELTDQMSFTDRVRNFISYRMQDYMFETLWKQWDSYYTKALGRPTTLCETMGKAEIWLMRTYWDFEFPRPYLPNFEFVGGLHCKPAKPLPKEMEEFVQTSGEHGIVVFSLGSMVKNLTDEKANLIASALAQIPQKVLWRYKGKIPDTLGSNTRLFDWIPQNDLLGHPKTRAFITHGGTNGIYEAIYHGIPMVGVPMFADQPDNIAHMKAKGAAVEVNMNTMTSSDLLNALRTVINEPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSLDVIGFLLACVASAILLVAKCCLFIFQKVGKTGKKKKRD", "length": 528 }, "evidence": [ { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080721-20", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080721-20#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060929-796", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-796#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8BWQ1-1", "protein_name": "UDP-glucuronosyltransferase 2A3", "gene_name": "Ugt2a3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVSEKCVAAFFLLQLCWAGCGFCSKVLVWPCDMSHWLNLKTILEELGARGHEVTVLKYPSIIIDQSKRIPLHFENIPLLYEIETAENRLNEIANLAVNVIPNLSLWEAAKTLQDFFLQVTGDFESICRSVLYNQKFMDKLRDAQYDVVVIDPVVPCGELVAEVLQIPFVYTLRFSMGYYMEKHCGQLPIPLSYVPVVMSELTDNMTFTERVKNMMFSLLFEYWLQQYDFAFWDQFYSETLGRPTTFCKTVGKADIWLIRTYWDVEFPRPYLPNFEFVGGLHCKPAKPLPKEMEEFVQSSGEHGVVVFSLGSMVKNLTEEKANLIASVLAQIPQKVLWRYSGKKPATLGSNTRLFNWIPQNDLLGHPKTKAFITHGGTNGIYEAIYHGVPMVGVPMLGDQPHNIAHMEAKGAALKVSISTMTSTDLLSAVRAVINEPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSLDVIGFLLLCVVTLTFIITKFCLFVCQKLYMKESKKMGNRKKKN", "length": 534 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080721-20", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080721-20#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060929-796", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-796#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8JZZ0-1", "protein_name": "UDP-glycosyltransferase 3A2", "gene_name": "Ugt3a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAHRRWLLMSFLFLEVILLEAAKILTISTLSASHYIVISRVSQVLHEGGHNVTKLLYESANIPDFRKEKPSYQVINWRPPEDQEKKFADLRHRLTEEITYGRSKHHTLLKIHQYFGDLCSQLLSRKDIMDFLKNENFDLVLLDSMDLCSLLIVEKLGKRFVSFLPFQFSYMDFGLPSAPLSYAPVYGSGLTDQMDFWGRVKNFLMFLDFSMKQREILSQYDSTIQEHFVEGSQPVLSDLLLKAELWFVNSDFALDFARPLFPNTVYVGGLLDKPVQPIPQDLENFISQFGDSGFVLVALGSIVSMIQSKEIIKEMNSAFAHLPQGVLWTCKTSHWPKDVSLAPNVKIMDWLPQTDLLAHPSIRLFVTHGGMNSVMEAVHHGVPMVGIPFFFDQPENMVRVEAKNLGVSIQLQTLKAESFALTMKKIIEDKRYKSAAMASKIIRHSHPLTPAQRLLGWIDHILQTGGAAHLKPYAFQQPWHEQYMLDVFLFLLGLMLGTLWLSVKVLVAVTRYLSIATKVKEA", "length": 523 }, "evidence": [ { "id": "RGD:1564365", "url": "https://alliancegenome.org/gene/RGD:1564365#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BY64-1", "protein_name": "UDP-glucuronosyltransferase 2B28", "gene_name": "UGT2B28", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALKWTSVLLLIHLGCYFSSGSCGKVLVWTGEYSHWMNMKTILKELVQRGHEVTVLASSASILFDPNDAFTLKLEVYPTSLTKTEFENIIMQQVKRWSDIQKDSFWLYFSQEQEILWEFHDIFRNFCKDVVSNKKVMKKLQESRFDIIFADAFFPCGELLAALLNIPFVYSLCFTPGYTIERHSGGLIFPPSYIPVVMSKLSDQMTFMERVKNMIYVLYFDFWFQMCDMKKWDQFYSEVLGRPTTLFETMGKADIWLMRNSWSFQFPHPFLPNIDFVGGLHCKPAKPLPKEMEEFVQSSGENGVVVFSLGSVISNMTAERANVIATALAKIPQKVLWRFDGNKPDALGLNTRLYKWIPQNDLLGLPKTRAFITHGGANGIYEAIYHGIPMVGIPLFWDQPDNIAHMKAKGAAVRLDFHTMSSTDLLNALKTVINDPSYKENVMKLSIIQHDQPVKPLHRAVFWIEFVMCHKGAKHLRVAARDLTWFQYHSLDVIGFLLACVATVIFVVTKFCLFCFWKFARKGKKGKRD", "length": 529 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080721-20", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080721-20#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060929-796", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-796#orthology", "database": "AGR" }, { "id": "RGD:708541", "url": "https://alliancegenome.org/gene/RGD:708541#orthology", "database": "AGR" }, { "id": "RGD:628623", "url": "https://alliancegenome.org/gene/RGD:628623#orthology", "database": "AGR" }, { "id": "RGD:620895", "url": "https://alliancegenome.org/gene/RGD:620895#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9HAW7-1", "protein_name": "UDP-glucuronosyltransferase 1A7", "gene_name": "UGT1A7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARAGWTGLLPLYVCLLLTCGFAKAGKLLVVPMDGSHWFTMQSVVEKLILRGHEVVVVMPEVSWQLGRSLNCTVKTYSTSYTLEDQDREFMVFADARWTAPLRSAFSLLTSSSNGIFDLFFSNCRSLFNDRKLVEYLKESCFDAVFLDPFDACGLIVAKYFSLPSVVFARGIFCHYLEEGAQCPAPLSYVPRLLLGFSDAMTFKERVWNHIMHLEEHLFCPYFFKNVLEIASEILQTPVTAYDLYSHTSIWLLRTDFVLEYPKPVMPNMIFIGGINCHQGKPVPMEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH", "length": 530 }, "evidence": [ { "id": "MGI:3576090", "url": "https://alliancegenome.org/gene/MGI:3576090#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9HAW8-1", "protein_name": "UDP-glucuronosyltransferase 1A10", "gene_name": "UGT1A10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARAGWTSPVPLCVCLLLTCGFAEAGKLLVVPMDGSHWFTMQSVVEKLILRGHEVVVVMPEVSWQLERSLNCTVKTYSTSYTLEDQNREFMVFAHAQWKAQAQSIFSLLMSSSSGFLDLFFSHCRSLFNDRKLVEYLKESSFDAVFLDPFDTCGLIVAKYFSLPSVVFTRGIFCHHLEEGAQCPAPLSYVPNDLLGFSDAMTFKERVWNHIVHLEDHLFCQYLFRNALEIASEILQTPVTAYDLYSHTSIWLLRTDFVLDYPKPVMPNMIFIGGINCHQGKPLPMEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH", "length": 530 }, "evidence": [ { "id": "MGI:3576090", "url": "https://alliancegenome.org/gene/MGI:3576090#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9HAW9-1", "protein_name": "UDP-glucuronosyltransferase 1A8", "gene_name": "UGT1A8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARTGWTSPIPLCVSLLLTCGFAEAGKLLVVPMDGSHWFTMQSVVEKLILRGHEVVVVMPEVSWQLGKSLNCTVKTYSTSYTLEDLDREFMDFADAQWKAQVRSLFSLFLSSSNGFFNLFFSHCRSLFNDRKLVEYLKESSFDAVFLDPFDACGLIVAKYFSLPSVVFARGIACHYLEEGAQCPAPLSYVPRILLGFSDAMTFKERVRNHIMHLEEHLFCQYFSKNALEIASEILQTPVTAYDLYSHTSIWLLRTDFVLDYPKPVMPNMIFIGGINCHQGKPLPMEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH", "length": 530 }, "evidence": [ { "id": "MGI:3576090", "url": "https://alliancegenome.org/gene/MGI:3576090#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9I7T3-1", "protein_name": "UDP-glycosyltransferase family 305 member A1, isoform B", "gene_name": "Ugt305A1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRALCLLPVFVLLGRFCSLEAANILCLVSTAKHNNPGWSKPLFDALLANGHSLLVISTAPNPEPKKQVDGLVYYHLPNEYDVMKRHFLLEEPREYISMVTLNQLLVWYEVLLGSCRALLNSDTMSSKRPELTAQLSMEYDLIITDVTQGIECLMDSVSGWRSKPVLGLSAGKLTPDLMSLLRAENTINAARIPHYISQVPKTMGFWNRLHNHIMYYAEPLIHLVITRPVLSELMKTENAFPKLQLVLLNTHPTLDYVQNLPPGVIEVGGLHIKNQTSPLPTYIQEFTEKFFDGIVYINMPYIEYMNDQGLKAMYTMIHGNPNVAFIWNVEQLEQLPAKKPNLLTLHVNQSLQQDILAMQYVKGFLNHGDSFSLQEAIHYGVPVVVLPLKLEEFNNAQRVMERNLGVMLQVKEFNQSSLSDALTRILDEERFISALHQAQLKFRTRPQSALELAVWHAEQLIAEPRLFKHFAQTETLAQNFFVANSLDVLTVPLIVLLAAVVSLANLVYVLYTGGSKRQQTLEKAVLKKRKKSKKSSPQTFTPVNVTLKLETSELLEDLNNEILEGEEELLKGEEKPLEEKKED", "length": 583 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-061103-373", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061103-373#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100406-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100406-3#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-23", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-23#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9V9X9-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt35D1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPPIFLLVCLLPGYSEGARILAVFPLPSSSHYFFALPYLKSLASLGHEITSVSPYPQREPFRNIHDIPVPEVFENFNEVLRIASTPRSTWQSSDFINEYVLNLTKTVLNNEGVRRDILGPQKPHFDLVIMDLWRMDVLSGLAAYFDAPIIGMASYGTDWKIDELMGNVSPISYLQSPSSRFYDLEAYGERLLHLMERTFSYMNYKWRHVRKQETLYSQFFPSVAERKPLSEISRNFDLVLVNQHFTLGPPRPYVPNMIQVGGLHVDHSTEALSAELDHFIQGAGESGVIYFSLGTNVKSKSLSEDRRKVLLETFASLPQRIVWKFEDELLPGKPPNVFISKWFPQQAILAHPNVKLFITHGGLLSTIESIHHGKPMLGLPCLFDQFRNMDHVRQVGLGLVLNIKQMTSEEFRSTIIRLLTNKSFEETARITAARYRDQPMKPMETAIWWTEYVLSHKGAAHMQVAGKDLGFVRYHSLDVFGTFLVGALVILGIVTYLLVMTLRKCLFLIKRGKCEAIKKIQ", "length": 521 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" }, { "id": "RGD:708541", "url": "https://alliancegenome.org/gene/RGD:708541#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061103-373", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061103-373#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100406-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100406-3#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-23", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-23#orthology", "database": "AGR" }, { "id": "MGI:2137698", "url": "https://alliancegenome.org/gene/MGI:2137698#orthology", "database": "AGR" }, { "id": "MGI:3576090", "url": "https://alliancegenome.org/gene/MGI:3576090#orthology", "database": "AGR" }, { "id": "MGI:3580629", "url": "https://alliancegenome.org/gene/MGI:3580629#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VCL3-1", "protein_name": "UDP-glycosyltransferase family 303 member B2", "gene_name": "Ugt303B2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRLGYAWLAFGLLLHLNLYLELGQAANILGVFPYRIPSPFQMVRPLIKALVERGHKVTMVTPADYPAKIDGVRHIRVPMLNQLMQNLMKNDQFFDALGDKWREGVLVSTIFYNVSHAILNNNGVQMLMRDKSIRFDMIMVEASHLDALYGLAEFYNATLLGISCMHMTWHIDYLAGNLAPSVYEPISPNGFALDNTFLSRWSNWIYITEEKLLERLVFRPAQVRLFKKFFGYPAEKLDELRARFSVILVNSHFSMGRVRANVPNIIEVAGVHLSEPPEPCGAELQKYLDEAEHGAIYFSMGQDILIKYLPENMQKQLLLVFLQMKQRVIWKSELSMLANKSENIYVMDKVPQRMVLAHPNLRLFITHGGLQSVMEAIDNGVPMLGLPLFFDQFNNIHRVQLAGMAKVLDPNDLNADTLIETIKELLENPSYAQRAKEMAASFRDRPMSPLDTAIWWTEYALRNRDTSHMRLNVEEIPLMRYYRLDSILTFGVRLGCVCGSLIFLGWRLYQKNRNRHTRLQERERVIAQIQLGLSNYEVVS", "length": 540 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061103-373", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061103-373#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100406-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100406-3#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-23", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-23#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VCL4-1", "protein_name": "UDP-glycosyltransferase family 303 member B1, isoform A", "gene_name": "Ugt303B1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRLRYCWLTLSLCLLLQHDRAQAANILGIFPYRHISPFFVMQPLVRTLATRGHNVTLITPIGMPNDIEGVRHIRVAQLNERIKEMLESDQVLDFMINKWTESALTAKALFNASNDILSDPGVQRMLHDKSESFDLIIMEPSSLDALYGLVEFYNATLMGLSSIRINWHTYELAGNPAPSIYEPISPVGFSLETSLFSRVYNWIHIMEEKLVNYLILRPAQLHLFQKFFGYSAQKMNELRSRFSLMLINSHYSMGKVRANAPNIIEVGGLHLSEPPEPSDEELQKFLDKADHGVIYFSMGNDILIKFLPENIQELLLQTFATLNESIIWKSELLYMPDKSDNVYVVEQAPQRHILNHPNVRLFITNGGLLSVIEAVDSGVPMLGLPMFFDQFGNMRWVQLSGMAEVMDINSLNKDTLTETIKHMLANNSYYLKAKEISQFFKDRPMSPLDTAVWWTEYALRNRNITRMRLNLEEIPLIEYYRIDSILAFSLRFGLVAASLIFLVYTLFLKYRIRLRRLHP", "length": 519 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061103-373", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061103-373#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100406-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100406-3#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-23", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-23#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VCL5-1", "protein_name": "UDP-glycosyltransferase family 303 member B3", "gene_name": "Ugt303B3", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MHLEFYWLAVLFCLFLQKDLYQDSVQAANILGIFSYHFSSHNLVVRPLAKALVKRGHNVTLITPVGMPTDIEGVRHIRVPKLNQRVQEMIEGDQILDFFGSKWIASLMVVSMLYNMSSDILSDKGVQKMLQNRNERFDLVMLEPSALEALYGVVEHYNATLMGFSGGNVNWSTEEVAGNFAPSINDPISSLGYSRSNSLLSKIYNWVHITEEKLLKHLIFRPSQLRIFKKFFNFSEQKFYNMREKYSVILVNNHISMGRVRSNVPNIIEVGGLHLTEPAEPCDSKLQKFMDDAEHGVIYFSMGQEIMVQFLPEDMQQNLMKSLDQFKQRVVWKTELYNMPNKSDNVYVIEQPPQRAVLAHPNTRLFITNGGLLSVMEAVYSGVPILGLPVFFDQFINLRNVNLRGMAEVLDANEMTLEILTSTIRKLLENPRYALKAKKMSQSFRDRPMSPLDTAVWWTEYALRNKDASHMRLNTEDVPLYYEWDWGLLLGLRFGIVFGSVIYLVYKLFQKTSARRRPFQVTGTVSQHPSLLDRRSQTQ", "length": 539 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VDA5-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt49B2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MILFMKLLFVCLLGTGDGARILAPFFLPVKSHFMMTDAIIRELVKRGHEVTFITPLSLAKENLGPNYREILLPKYDTWADISAMMKTKSALDMIDMSKLTHMRLAQHIGIKSTDFALAHPEVQELIYAKDKKGKFDLLLVEQFHNEGALMLGYIYEIPAITIATFAYANYFSQVFGFVNPLSYVPNVFLSCTDRMSLWERLENVVISTAEDVVREVSYYPQQDAVIRKHFSSLLPRVPTVKQLEQNISVILLNSYMPLTSPRPMSQNMISVGGLHILPPKPLPEHIKNYLDNAEHGAIYFSLGSQVRSADMPAEKLQIFLDVFASLKQRVLWKFEDDQLPNLPDNVKVEKWLPQADILAHPNVKVFIAHGGLFGMQEAVYHAVPVLGMPFYFDQDINIKAGQAAGYAIGLDYRTISKDQLKSALHALLKDPKYQANMMKASRIFRDRPLGAMDTAMYWINYVVEHRGAPHLVAAGVHLPWYQFYLLDVSAIILAITLLPLLTLYAVSRNYKSFRGIRAQKKEAKTE", "length": 526 }, "evidence": [ { "id": "MGI:2146055", "url": "https://alliancegenome.org/gene/MGI:2146055#orthology", "database": "AGR" }, { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080721-20", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080721-20#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060929-796", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-796#orthology", "database": "AGR" }, { "id": "SGD:S000004179", "url": "https://alliancegenome.org/gene/SGD:S000004179#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" }, { "id": "RGD:708541", "url": "https://alliancegenome.org/gene/RGD:708541#orthology", "database": "AGR" }, { "id": "HGNC:28183", "url": "https://alliancegenome.org/gene/HGNC:28183#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061103-373", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061103-373#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100406-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100406-3#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-23", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-23#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VG29-1", "protein_name": "UDP-glycosyltransferase family 37 member A3", "gene_name": "Ugt37A3", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVLRVEKFLLLAIAIGAVMGSSQGANILGLFPSLSPSHLIIQMSAAKVLAENGHNVTVVTVLKPVVNHKNITVIQVPLSKEEAQQMSDTIGAMSKNDNSNMALSLLRMSDQMDFMIRKNAETLMNDRVRDLYLNRGNKFDLVISGYFMNDFQLGFARKVNAPVIVLATMPPNHLLNPLIGNPLEVSYAGISNPAEGSKAVTFQRRLSSYMQSLGFGVFSHLSERRNRNWYKEVYGNDPKMPEYSEMLKNTSLVFFSSHAASEGPIRPNVPSAIEIGGIQIKDKPDPLPQNIAEFLGNATDGAILLSLGSNVQGKHLNPDTVAKMFNVLSKLKERVIWKWEDQENTPGKSANILYSKWLPQDDILAHPNIKLFINHAGKGGITESQYHGKPMLSLPVFADQPRNANAMVKSGFGLTLSLLTLEEKPFQEAILEILSNPQYAERVKSFSTLYRDRPMTARESFLYWTEYVIRHHGAAHLQSPLVHMSFIAANNIDICFLIFVILVSVLVLIKFLVQFIYRRFISKPKKEKTH", "length": 530 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VG30-1", "protein_name": "UDP-glycosyltransferase family 37 member A2", "gene_name": "Ugt37A2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVHKSGIYLLLATAICVLGGCHGANILGVFTSLSPSHLIIQMSTAKVLAERGHNVTVITVLKPVVNHKNITVIMVPLTKEESQQMSDTIGAMSKTDNSNMILSMLRMMGQMEFMFDKMAGALKDDRVRDLYLNRDNKFDLVLSGYFMNVYQLGFAKKVKAPVIVVATMPPNQLLNPLIGNPLEIAYVPSISDSVEKGKGMSFRQRLAGYSSSFFFGIFDFVTQRRSKRLYKELFGDDPNMPEYSELVKNTSLIFFASHAPSEGPIRPNVPAAIEIGGIQVKDTPDPLPQNMAEFLGNATDGAILLSLGSNVKGSHINPDTVVKMFNVLSKLKQRVIWKWEDLEKTPGKSDNIFYSKWLPQDDILAHPNIKLFINHAGKGGITEAQYHGKPMLSLPVFGDQPGNADVMVKQGFGLTQSLLSLEEQPFKEAILEILSNPQYFDKVASFSSLYRDRPMSARESVIYWTEYVIRHHGAAHLQSPLVHMSFIAANNIDIYALIAVVLVILVLLLKLLLQFIYRKIFAKPKKEKKH", "length": 530 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" }, { "id": "RGD:708541", "url": "https://alliancegenome.org/gene/RGD:708541#orthology", "database": "AGR" }, { "id": "MGI:2137698", "url": "https://alliancegenome.org/gene/MGI:2137698#orthology", "database": "AGR" }, { "id": "MGI:3576090", "url": "https://alliancegenome.org/gene/MGI:3576090#orthology", "database": "AGR" }, { "id": "MGI:3580629", "url": "https://alliancegenome.org/gene/MGI:3580629#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VGS7-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt303A1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFSGPGIAGLLLTVLLFGLLCPKLTNAENILAVFSYTFGSSYLLITPFLRNLVQRGHQLTLISAVTIMPHIEGVHHIRVPKLDMLMKILLDFEYDTDLTKWTEAQFLSEYFYNCSKFVLEDPGVQELLRNASAKYSLIILEASHNDALYGFSQHFNAPLLGVAAYGSSWNIDFLVGNSAPSVYEPMSALGYTSGLNLIEKWHNLIYITEERLVERFIYLPRQIDLYKQHFPGATTSIHDLRRRFSLVLINQHFTMGRVRSNVPNIVEVAGMHLDEKPYPLDAELKKILDEAEHGVIYFSMGLQLLDHWLPPGMRASMSDAFAQLKQQVIWKTDYPEMVNQSRNVFARTWFPQRAILNHPNVKLFITHAGLLSLIESVHYAVPLLCIPLFYDQFQNTKRMEKLGVARKLDFKNLFRDEIVLAIEDLVYNASYKRNARDLSQRFHDQPMSAMDTAIWWTEYILRHKGADHMRIAEQEMSLMQYYNVDVVSVLFGRIGLSAIIVIFLGWKLVSLATRHLEYRLNVPMVR", "length": 526 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061103-373", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061103-373#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100406-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100406-3#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-23", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-23#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VGS8-1", "protein_name": "UDP-glycosyltransferase family 304 member A1", "gene_name": "Ugt304A1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFPPGRWLLPMFWLISNSICWIRSSRILVIAPFESHSQCMLVTPYIQALKDRGHQLTVIHAYKHCMHKIEDVTFIRIWYNNNVFLEFEESVGIASANNKWEEISSMSSLMANATLNVLNNVEVRALMKSRITFDAVVLEAGYSDVLYGMAAHFSAQLIGICTCVADWNINNLVGFSTSTLTEPIMPFRAKYVKNVWDRIYNWLYTTEEWLLINLVFLPKQRLIHDHFFGHLEKSFHEIRQDFALMLLNQHFSLFRARPNVPGMVEVAGLHIPKEDPQLPSDLQVFIDEAEHGVILFSLGLEQDSKDLPRKTQEILVETFKSVPQRVIWKFDGESTMSLGTDIYHSKLLPQQAILAHPNVKLFISHCGMMSVIEAAYYAKPVLGLPSFFDQFRNLEIMKEEGVALELNINSLTVKELKDAIHSMINEPEYRESALAISQRFRDQPIHPLDAAIYWTEYIIRYKGADHMKISQSQLKLFDYYSLDNFIMVGSRLSLVVALVFLVLSKSRRWLNHLSTSAKSFLPTKHLIRS", "length": 529 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061103-373", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061103-373#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100406-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100406-3#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-23", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-23#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VGS9-1", "protein_name": "UDP-glycosyltransferase family 35 member A1", "gene_name": "Ugt35A1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGGIFSVTGLGILLIGLIWLFAANADEGVQSSRILAVFPFPGRSQYIFAEQFMKELAHRGHNVTVINTFGSDKNEPNFRVIGAKKIHEIMAAFGNADYTQTASQWQMLTMTTQFLNLLTTSILDDAAVKDLLNSGEKFDLVIMEAVQTEALFGLIQHFGAETIGISSYGTDTHIDELMGNISPLSYNPLLLSSRTEQMDFKDRVMNVFEASVMWLHKRIVHLPSQRDLYAKYFPTARKSLDEVLDSFALMLLGQHFSLSYPRPYLPNMIEVGGLHLQQKRKVQPLAKELSEFVEQSEKGVIYFSMGSNIKSKDLPPSTRKMLMQTFASVPQRVLWKFEDDQLPEKPDNVFISKWFPQPDILAHPNVKLFITHGGLLSTIESIYFGKPILGLPIFYDQHLNVQRAKQVGYGLSADIWSVNATELTPLIQELLSNPSYAAAAQTKSKLFRDQKETALERAIWWTEYVLRHKGAKHLRCASRDLDFIQFHGLDTWGLLIAITFVSLLIVVILIKCLQRVFVSLISKIRKNRAEASKLKTQ", "length": 537 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" }, { "id": "RGD:628623", "url": "https://alliancegenome.org/gene/RGD:628623#orthology", "database": "AGR" }, { "id": "RGD:620895", "url": "https://alliancegenome.org/gene/RGD:620895#orthology", "database": "AGR" }, { "id": "HGNC:28183", "url": "https://alliancegenome.org/gene/HGNC:28183#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061103-373", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061103-373#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100406-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100406-3#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-23", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-23#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VGT0-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt35B1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLALRIGFLLLTLPASMQAARILAIFPFPGPSQYINVVPYLKELANRGHQVTSVNAFPQKKPVVNFRDVFIPDVFNNYKELINELSGPMNLWQENNFINKFFVSVTRCVLTNKEVTETLLPPGKDHFDLIIVEALRSDAYYGFAAHFNAPIIGISTFGTDWNIDALVGNESPLSYTPLATGGLTDRMTFLERLSNFVDTTVAWLNYRFVHMSEQEKMYAKYFPEASKRVQLTDLNRNFSLVLLNQHFSLSFPRPYVPNMIEVGGLHISHKPAPLPKDLEEFIQGSGEHGVIYFSLGSNVLSKDLPADRKDLILKTFASLPQRVLWKFEDDKLPGKPSNVFISKWFPQPDILAHPKVKLFITHGGLLSTIESIHHGKPVLGLPFFYDQFLNVRRATQAGFGLGLDHTTMTQQELKETIEILLKEPRFAQIARQMSERYRDQPMSPLDTAIWWTEYVLRHKGAYHMRVAGQDLGFFAYHSLDVIGVLLGGALLLVAIIVGVLGKLTDFGNAKKKLKSK", "length": 516 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" }, { "id": "RGD:628623", "url": "https://alliancegenome.org/gene/RGD:628623#orthology", "database": "AGR" }, { "id": "RGD:620895", "url": "https://alliancegenome.org/gene/RGD:620895#orthology", "database": "AGR" }, { "id": "HGNC:28183", "url": "https://alliancegenome.org/gene/HGNC:28183#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061103-373", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061103-373#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100406-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100406-3#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-23", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-23#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VGT1-1", "protein_name": "UDP-glycosyltransferase family 35 member E2", "gene_name": "Ugt35E2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPMSMLVLRLIVLVVALLPVLLEGARILGVFPIPSHSHYYHALPYLKKLASLGHEITSVSPFPLKEPVANIHDIPVPELFDNIEEIVGNLTNRKGTWNEFEYINQYTLGLVEKVLENDGVRREILQPESLQFDLIIVDLWRLDALYGLAAYFDAPIIGIASYGTDWKIDELVGNVSPLAYLQSPSFNWFDLDTYGGRLGHFVDQSMAWINWHWRHEERHEAVYRKYFPKIADKRSLSEITRNFALILVNQHFTMAPPRPYVPNIIEVGGMHVDQQPKALPQDLEDFIQGAGEHGVIYFSLGTNVRSRNLSKDRRKILIDTFASLPQRILWKFDADELSDVPSNVLISPWFPQQDILAHPNVKLFITHGGLQSTVECIHRGVPMLGLPFFYDQFRNMEHIKAQGIGLVLNYRDMTSDEFKDTIHQLLTEKSFGVKAKRTADRYRDQPMNPLDTAIWWTHYVLRHKGAPHMRVAGRNLDFITYHSLDVLGTFLLAVWAILSIVVLCAIKLLRAILKSKKGNISPKQKIN", "length": 527 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" }, { "id": "HGNC:28183", "url": "https://alliancegenome.org/gene/HGNC:28183#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061103-373", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061103-373#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100406-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100406-3#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-23", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-23#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VGT2-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt35E1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLASGLFYLIILLFPGFLYGARILALFPVPSHSHYYHALPYLKNLASLGHEITSVSPFPSEEPVKNIYDIYVPEVLNSFDELLKQMTTPKNTWEFFDATNEFVYNITKDVFNNDGVRREILRPGKAQFDLIIVDIWKYDAFYSLAAYFEAPIIGLAPCGIDWKIDEMVGNPSPMSYLQSPSSYLYNLDTFGGRVAHVVEVAISWFNWHWRYEQKHEALYKKYFPKIAETKPLSEISQDIALVLVNQHFTLGPPRPYVPNVIEVGGMHIDEQPKALAQDLEDFIQGSGEHGVIYFSLGTNVRTKNMVDDRKRILIEAFGSLPQRVLWKFEDEELQDIPSNVLVRKWLPQQDLLAHPKVKLFITHGGMQSTIESIHYGKPMLGLPFFYDQFTNVDHIKKHGFCLSLNYHDMTSDELKATILQLLTEKRFEVTARIAGARYRDQPMKPLETAVWWTHYVLRHKGAPHMRVAGRKLSFFTHHSLDVLGTVLLVILLVIIAILLIIVFSVCKISKNISTRLVVKKQRKQKVR", "length": 527 }, "evidence": [ { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" }, { "id": "RGD:708541", "url": "https://alliancegenome.org/gene/RGD:708541#orthology", "database": "AGR" }, { "id": "HGNC:28183", "url": "https://alliancegenome.org/gene/HGNC:28183#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061103-373", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061103-373#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100406-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100406-3#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-23", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-23#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VGT3-1", "protein_name": "UDP-glycosyltransferase family 302 member C1", "gene_name": "Ugt302C1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKPTAGQTGFLALLLFCLLSCVSAYNYLVVLHTAARSHYHVGSALAKGLAAAGHQVTIISPFELKKPIKNIKDVPAKSILTSMQGRIANLLQSSKEPIIKQIINFHEMGIEITELLLKEPSVIELMKSNQTFDAVISEVFLNEAHFGFAEHFKAPLIGLGTFGAISWNTDLVGSPSPPSYVPSALLKFSDRMSLVERVGNQAFLTYEYIFLNYFYLPRQEVLYRKYFPNNKQDFYDMRKNTALVLLNQHVSLSFPRPYSPNMIEVGGMHINRKRQPLPKDILEFIEGAEHGVIYFSMGSNLKSKTLPLEKRQALIDTFAQLKQRVLWKFEDTDLPGKPANVFISDWFPQDDILAHDNVLAFITHGGLLSTTESIYHRKPFVGIPIFGDQFLNMARAEQNGYGVTVHYEELSSAKLLAAIQKIINNPEATQRVRDMSDRYRDQQQTPLERAVYWVEHVSRHKGAKYLRSASQDLNFIQYHNLDAMLILYGGIIFVLYCIFLLIRLVWRLLQELFIKKDTSKPKQKAKRN", "length": 528 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" }, { "id": "RGD:708541", "url": "https://alliancegenome.org/gene/RGD:708541#orthology", "database": "AGR" }, { "id": "HGNC:28183", "url": "https://alliancegenome.org/gene/HGNC:28183#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061103-373", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061103-373#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100406-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100406-3#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-23", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-23#orthology", "database": "AGR" }, { "id": "HGNC:12545", "url": "https://alliancegenome.org/gene/HGNC:12545#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VGT4-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt302E1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRWLLNSWLLLILALFGQSWGYSYLMISHTASKSHYAVCFALAKGLAAAGHEVTLVSPFPQRKPIKNIIDVETPNIITVMGVYKARILENAKKPVLLRYPRISLMGLDITESLLKEPKVQELLKQNRTFDGVICETFMNDAHYGFAEHFGAPLITLSSLGATGWTSDLVGTPSPPSYVPHSLLRFGDRMNFWERAQNLGFQIYEFAYENLINLPRHEALYRKYFPNNKQDFYRMRKDTSLVLLNNHVSISNPRPYSPNMIEVGGMHVNRKAPKPLPQNIRKFIEEAEHGVIYFSLGSNLNSKDLPENKRKAIVETLRGLKYRVIWKYEEETFVDKPDNVLISNWLPQDDILAHEKVIAFITHGGLLSTMESIYHGKPVVGIPFFGDQFMNMARAEQMGYGITVKYAQLTASLFRSAIERITSDPSFTERVKVISSQYRDQKETPLERAVYWVEHVTRHKGAKYLRSACQDLNFIQYHNLDVLATFFSVIGLTVIFVFLLVRFLVTIVNGFLYKPSSKLKIN", "length": 521 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "SGD:S000004179", "url": "https://alliancegenome.org/gene/SGD:S000004179#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" }, { "id": "RGD:628623", "url": "https://alliancegenome.org/gene/RGD:628623#orthology", "database": "AGR" }, { "id": "RGD:620895", "url": "https://alliancegenome.org/gene/RGD:620895#orthology", "database": "AGR" }, { "id": "HGNC:28183", "url": "https://alliancegenome.org/gene/HGNC:28183#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VGT5-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt302K1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRTFTLILGLLCSLGYSSGYNYLMVLNSAGRSHFNVGHALAKGLVKAGHTITVVSVFPQKKPIPGYTDVSVPNVIEVMGGDIGALWASIQKTYTQNLIDHYQMGFRITRGLFEDSNFQDFLKSNQSFDAIICETFYNDAHYGLAEHFNAPLIGLATGGGLTFITDMVGSPAPASFVPHIMLPFNDHMSLYERLLNVAFLGYERVLLDYYFLPTQEKLYKEFFPGNKRCFYKMRRNASLVLINQHVSLSFPRPHSPNMIEVGGMHIDGKWNPLPEKIERFINESEHGAIYFSMGSNLKTKDLPPSKVQEILKALGGLKQRVLWKFELDNLPNKPENVYISDWFPQTDILAHPKIMAFVTHGGMLSTTESIYHAKPVIGLPIFSDQFFNMAHAEQNGYGIMLDFKTLNAVEFRKAIERITSEPSYTKVVQGISFRYRDQQQTPIENAIYWVEHVTRHQGAAYLKSAAQRLNWWQYHNVDVLLIIFVVMVLLLIVLPITIYKLLKKLLLKGERTQSTKVKRN", "length": 519 }, "evidence": [ { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" }, { "id": "HGNC:28183", "url": "https://alliancegenome.org/gene/HGNC:28183#orthology", "database": "AGR" }, { "id": "MGI:2137698", "url": "https://alliancegenome.org/gene/MGI:2137698#orthology", "database": "AGR" }, { "id": "MGI:3576090", "url": "https://alliancegenome.org/gene/MGI:3576090#orthology", "database": "AGR" }, { "id": "MGI:3580629", "url": "https://alliancegenome.org/gene/MGI:3580629#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VGT8-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt35C1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRLLTVIAIVFCALSAKPLESESAKILATLPFPGRSQYIFVESYLKALAAKGHQVTVINAFKNKETPNMRFIEALKAHEFADEMMSLLNVPLLWQQLNAMDYILNKFIDVTMEDEGVQRLLNSGETFDLVLAEMLHMEPMYAFAQHFNATLVGFSSFGTDRTIDEAAGNISPISYNPLVTSPRTDRMTFLERLENHYEVIVEDIHRHFVHLPHMRNVYKKYFPNAKKTLEEVMDSFSLILLGQHFSLSYPRPYLPNMIEVGGMHISHKPKPLPEDIKQFIEGSPHGVIYFSMGSNVKSKDLPQETRDTLLKTFAKLKQRVLWKFEDDDMPGKPANVLIKKWYPQPDILAHPNVKLFISHGGLLSSTESVYFGKPILGLPCFYDQHMNVQRAQRVGFGLGLDLNNLKQEDLEKAIQTLLTDPSYAKASLAISERYRDQPQSAVDRAVWWTEYVIRHNGAPHLRATSRDLNFIQLNSLDTLAVILAVPLLLALLIVTLSCKLLGGKKQKCLHADKLKKH", "length": 517 }, "evidence": [ { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" }, { "id": "RGD:628623", "url": "https://alliancegenome.org/gene/RGD:628623#orthology", "database": "AGR" }, { "id": "RGD:620895", "url": "https://alliancegenome.org/gene/RGD:620895#orthology", "database": "AGR" }, { "id": "HGNC:28183", "url": "https://alliancegenome.org/gene/HGNC:28183#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061103-373", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061103-373#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100406-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100406-3#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-23", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-23#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VIM9-1", "protein_name": "UDP-glycosyltransferase family 37 member A1", "gene_name": "Ugt37A1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVGRTKSYFVIVLALTLLIYGAQGANILGLFPSLSPSHLIISMSVAKILAEQGHNVTVVTVLEPTITHKNINLVTVPMTKEEIKQRSETIGAKQKNTSSNRFISILNMSGQMDSMLRKMADVLKDQRVKELYLNKDNHFDLVISGYFMNDYQLGFARKVNAPVVVLAPSPPSQMLNSLIGNPHDKVEKEKGMTFGQRLDSYISSLLYGIFLRQIDQRNRQYYNEIFGDDPTMPEYTDILRNTSLVFFCSHAASEGPIRPSVPAAIEIGGIQIKDKPDPLPKNLEKFLGNATHGAILLSLGSNVQGSHIKADTVKKIFSVLSNLKQRVIWKWDDLDKTPGKSDNILYSRWLPQDDILAHPSVKLFINHAGKGGISEAQYHGKPMLSLPVFGDQPGNAHAMVKSGFGLTLSLLTLEEEPFRAAVLEILSNPKYSQRVVKFSSLYRDRPASARESLIFWTEYVIRHHGAAHLQSPLVHMDFIAANNLDIYALIGAISIGLLLMLKKVVQITCRRLRTKLNKVKKQ", "length": 522 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VJ45-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt36E1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MCGCWKVFCLLALLSLVAFSDSLRILGLFPHPAISHFKFFHPIMRGLAEAGHSVDVISPFEDKDPPNGYKDHLLPPSTLTDTISLEDFERPYSFLFHYVEFFILHKMGREDCNTTLHSRALTEILKNPPGYYDVILLEQFNTDCAMSVAHVFQAPVIGMSSCALMPWHYERFGAPLIPSYISALFQGQSQEMSFAGRLGNWITVHSLNLLYKMFTVPAGNALIRQRFGPGLPSTEDLVRNTSLMLVNQHFSLSGPKPLPPNVIEVGGVHISPPKPLPSDLQKILDNAPKGVILISWGSQLKACSLSAARRDGIVKAIGRLEQEVIWKYENDTLPNKPPNLHIRKWLPQRDILAHPNLKVFMSHGGLMGTTEAVSSAVPIVGVPIYGDQSLNIAALVQRGMALQLELKKLDENTVYEALTKALDPSFKARAKEVASSYNNRIQGPLETAIWWVEHVAETKGAPLTQPSAVHLSRFVYYSLDVYSVVALSLLLPVITLLGLIRMFKRREPKGDRKLKRK", "length": 517 }, "evidence": [ { "id": "MGI:2146055", "url": "https://alliancegenome.org/gene/MGI:2146055#orthology", "database": "AGR" }, { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "SGD:S000004179", "url": "https://alliancegenome.org/gene/SGD:S000004179#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VJ46-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt36D1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MWSPRVALLFLALALSQPDELVEAAGPLKVLGLFPHPGVSHFHFFHPIMKGLAEAGHDVSVVSHFPDKHPVAHYKDFPLTGMDKLTNSVDLKFFEKRTFYSHFQEFFLLYDWGKQTCNLTLRSEALQQILRRPGRFDVIIMEQFNTDCMMGVAHQLQAPVIALSSCVMMPWHYERMGAPLIPSHIPALFMAQSQHMNFGGRLANWFSTHALNWMYKLLSVPAADAMVQYKFGHDVPSVGELVKNTSMFFVNQHYSLSGPKVTPPNVIELGGIHIQKSKPLPADLQRILDNAEEGVILISWGSMIRANSLSAAKRDGIIRAVARLKQKVIWKWENETLPNQPPNMHIMKWLPQRDILCHPNVKVFMSHGGLMGTSEAAYCGVPVVATPMYGDQFVNTAALVERGMGTILNFEDIGENTVMRALKKALDKKFHDAAKVVSHSFHHRPQQALHTAIWWVEHVAHTGGAPLLKPSAVEMSRFVYYSLDVYAVLALVLGSIIASWVWLLRLCCGSSAAQKTKKD", "length": 519 }, "evidence": [ { "id": "MGI:2146055", "url": "https://alliancegenome.org/gene/MGI:2146055#orthology", "database": "AGR" }, { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080721-20", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080721-20#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060929-796", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-796#orthology", "database": "AGR" }, { "id": "SGD:S000004179", "url": "https://alliancegenome.org/gene/SGD:S000004179#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" }, { "id": "RGD:708541", "url": "https://alliancegenome.org/gene/RGD:708541#orthology", "database": "AGR" }, { "id": "RGD:628623", "url": "https://alliancegenome.org/gene/RGD:628623#orthology", "database": "AGR" }, { "id": "RGD:620895", "url": "https://alliancegenome.org/gene/RGD:620895#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VJ47-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt36F1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKLLPLALLAFLLRPKPNDAAHILGLFQHPGKSHFDFFRPMFLALAERGHNISMYSYFPLEKPVANYTDYVFQGMPLLTDIVDLSNFESEWKPLGLPFKVPTYFMLHDWGLRSCKVALNSPLITQLLKSPIRYDVILLEHFSNDCMAAVAHLLNAPVIALSSCAIMPWHYKRMGSPFINPIMPMNFLPYTDEMSLIDRLNNFFHFHTVNTLYNMITQPATDALIAERFGPGLPPINEIVKNTSLMLINQHYALTGPRPYAPNVIEVGGLQVGPIKPLPQHLLDLLDRSPNGVIYISWGSMVNSNTLPSGKRSALFQSISQLKEYNFVMRWKSLESLEDKQPSNLYTFDWLPQRDLLCHPKIRAFISHGGLLGTTEAIHCGVPMLVTPFYGDQFLNSGAVKQRGFGVIVDFRDFDSNHITRGLRIILDKKFAERVRRSSEAFRQRPIPPIKLATWWIEHVIKYGGAPHIQSEARHINWIVYNSIDVLLFWLGILFLLIVALRKLIKIFKTAFCRGKISRDTKTKTQ", "length": 525 }, "evidence": [ { "id": "MGI:2146055", "url": "https://alliancegenome.org/gene/MGI:2146055#orthology", "database": "AGR" }, { "id": "SGD:S000004179", "url": "https://alliancegenome.org/gene/SGD:S000004179#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VJ81-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt301D1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEMQLQWKCWMLIFLIGLLEFGAGSRILFMGPFPAPSHWLWLEHFQNDLLRQGHHVTSVNNHPTKHPHENLTEIIISPSFDIPKHFPKENIFSMQFVSDFNNLELWWTIGLMTTEHAFKDPKVKKLIESKDDHYDLVIIEQFFHEAFLMFGKRFNCPVVTIGTMGYADNIDHAMGILTPWSLIPHLLLSHTDRMTFGQRAYNAYLSLYDAVMRRWVYLPKMQKLAEKYFQGSIEGPLPNVLDLERNISLVLINAHRSIDLPRPSMPGLIDVGGAHIQKPKQLPTDLQNFLDNATYGVIYFSMGSYVKSTDLPQEKTALILKAFGQLKQQVIWKFENDSIGDLPSNVMIKKWMPQNDILAHPNVKLFITHGGIFGTQEGIYWGVPMLCVPLYGDQHRNTIKSVREGYARSLVFSKLTTDDLVRNIETLINDPQYKRSALEVSQRFRDNPIHPLDEATFWIEYIIRHRGARHLKSHGAFIPLHQYLLLDVLGCLLLGAFLAIWLPWRMIRRVHKWWLKGESSNKLNEGKKRL", "length": 530 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080721-20", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080721-20#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060929-796", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-796#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" }, { "id": "RGD:708541", "url": "https://alliancegenome.org/gene/RGD:708541#orthology", "database": "AGR" }, { "id": "RGD:628623", "url": "https://alliancegenome.org/gene/RGD:628623#orthology", "database": "AGR" }, { "id": "RGD:620895", "url": "https://alliancegenome.org/gene/RGD:620895#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VJH8-1", "protein_name": "UDP-glycosyltransferase family 37 member D1, isoform C", "gene_name": "Ugt37D1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTQNRSTWIGCSLGGLLVALLALQTMPQGTEGANILGVFTSHSPSHFIVHMSIMKTLAEKGHNVTVVSSVPPKVTHKSINHIVVPMSAEDEKVLNDGMAGMVKEKPSIWNTMKSIFSSLALLIDKQVDVLEDPRFQELYLNKGNKFDVVFVGFFFNTYQVALGARFNCPVIISWSGPPMMMVNEVLGNPELSSVPQMHISAPPGQPMNFQQRMQNFASTLGFNALNIFLNHKYNKFYDRLWSKDKSMPTFAQAKRNVSLAFCNGHGISEGPIRPNVPGVIEIGGIQVKSKPDPLPEDIQEFLEKGKHGAILFSLGSNLKGEHIQPEVVKTIFKGLSSLKQQVIWKWEDPKNTPGKSANILYKKWLPQDDILAHPKLKLFITHAGKGGVAEAQYHGVPMLALPVFADQPGNADKLVASGYGLQLPLATLDVDEFKAAIKEVIENPKYAKTLKSFSQLYRDRPLSPQESVVYWTEYVIRHHGAAHMQSPLVHMNFIASNNLDIYIIAALVLYIVFIINKIVWKFVWRKLFGKSNKVSKGKKVKKQ", "length": 543 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VJH9-1", "protein_name": "UDP-glycosyltransferase family 37 member E1", "gene_name": "Ugt37E1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MIEYTKIGFLIAFLLSTMTQSSGGANILGVFGTHSPSHVIVHMAVMKALADRGHNITVVTQMKPKLATHENITVIIAPPTEERQRYIKEYMAEVSNEKPSFWETMVKAIVQSSNQLEGQYEFMTHPNVKEIYENPKIKFDLVFLGLMANTYQLGIAAKLKCPVIISWVGIPLPFMDTIVGNVNDPSYVPTVNVALNAGQKTMDFGLRFVNFFKYAIMCVFETVLDYKMNQFYERAFANELEFPNYHEMKRRVSLLFYNYHSASEGPIRPTVPQSIEIGGIQVKEQADPLPKELAKFLDKADEGAIFFSLGTNVNTNTFRPDTVDILYKVLSKLPQRVIWKWEDLKNKPGNASNIFFGNWLPQDDILAHPNTKLFITHAGKGGVAEAQYHGVPMVALPIFGDQQGNAEIMTKSGFGRWLDILTMTEHELEQTIREVLGNPAYRETIGKFSTLYRDRPLTARQSVIYWTEYVLRHQGALHLQSPLIHTKFVARNNLDVYGVVLLVSLLLIVTIKFLFRKILNVAIGYGSQRKAVANKLKNN", "length": 539 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" }, { "id": "MGI:2137698", "url": "https://alliancegenome.org/gene/MGI:2137698#orthology", "database": "AGR" }, { "id": "MGI:3576090", "url": "https://alliancegenome.org/gene/MGI:3576090#orthology", "database": "AGR" }, { "id": "MGI:3580629", "url": "https://alliancegenome.org/gene/MGI:3580629#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VJI0-1", "protein_name": "UDP-glycosyltransferase family 37 member C2, isoform B", "gene_name": "Ugt37C2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MIGVHFVFLLLLGVVASTQGANILGLFSSHSPSHLIIHMSVAKALVKAGHNVTVVSMLKPKVTHKDIHLIVVPMKEEQERIMEDQMTEMAGQKNSLVSTMYRLLTSMDVMINAQAELLSDPRFQRIYETKFDLMILGYFINDFQLGVAHKLKVPVIINWMSAPVPAIDKYTGNPSELSYVPLMGTVATQPMGFLKRTENALKSLLFEFIFVVFDYKLTRIYNDVFPEQDMPTLKELRKNISMAFVGSHLISEGPIRPLVPALIEIGGIQVKDKPDPLPKDIDQFISNAKQGAVFLSLGSNVKSSTVRPEIVQIIFKVLSELKENVIWKWEDLENTPGNSSNILYKNWLPQDDILAHPNTKLFITHAGKGGITEAQYHGVPMVALPIFGDQPGNAALMEKSGYGLALDLLSITEDSLRDALKEVLENQKYKQAIGQFSTLYRDRPMTAKQSVVFWTEYILRHQGAPNLQSPSVHMNFIQLNNLDIYALIVTILVLFVLLTRLVAKIVWNKFGGKAKISQTKKKQ", "length": 523 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" }, { "id": "RGD:708541", "url": "https://alliancegenome.org/gene/RGD:708541#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VM44-1", "protein_name": "UDP-glycosyltransferase family 307 member A1", "gene_name": "Ugt307A1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKRSPISWSLLWMGYTCIFLLADSPAPVESHHILGLFVNVHRSQLMVHLAVCRALLQRGHHLTLVTTLPLEEQEIQGNVSHIYIPWQQPKEEVSSSDLILRLERMFRRLEHSGDLLDLPEWKMFLRNQPNTPYDLLLLGYHFNDHLLGVAAHFNCPVAIVSTQQPTGFVNSLMGNPEERWYVPQPYDGQQRSGISAWVFGMWEKFMEILARRVLARIYRLHFPEPQYPSFETMRRSVVLALSNHHMISEGPIAPLIPSMVDIGGIVLEQQLDKTPLEISAGNRSLIIFSLGTRFTWRKSTKELVRTFTKAFAQFPDYDIYWTYDGPNGSAISLDYPHLKVAKWWPQTQMWQSGKVRLFITHGGKGSVSEALFYGVPMLGLPLIGDQRDNLQRMQSKNWGLTLSTNNLTHWKLAKAITRMLSDSSYGETILKASQLYRDRPVSPSDLVTYWIEYIVRHKGAKNLHNPARQLNIIEYHSIDVYFIVYGLLILTIAILRKVNSLL", "length": 502 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-061103-373", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061103-373#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100406-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100406-3#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-23", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-23#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VMG1-1", "protein_name": "UDP-glycosyltransferase family 37 member B1", "gene_name": "Ugt37B1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGGISRCLALQIVVLIAGAHGANILGLFTSLSPSHLVIQMSMARILAERGHNVTVVTILKPPSLHKDINHILVPMEEDILQAFNSVVGGMTKTDNSNAYVSMFRSVRQLSETFSKMGDVMKQPLVKDLYEHPDNKFDLVMVGYFMNCYQLALAHKLKVPLVVALSNPPSFLGYLLGNPWEVSYVPGMSVSIKGGKPLGFGHRVLNLLGSMAQRLFMFIIELRNARIYREIYGDDPTLPSYEDLHKNISLIFFASHGISEGPIRPNVPAVIEIGGIQVKEQPERLPQNMEQFLSEAPNGAILLSLGSNLKEDHLKSSTVQKMFNVLSKLQQKVIWKWDDLDNIPGESENILYSKWVPQVDVLAHPNITLFITHAGKGGLTEAQYHGKPMLALPVFGDQPSNADVMVMHGFGIKQSILTLEEDSFLQGIREVLDNPKYATAVKSFSTLYRDRPLSPRETLIYWVEYVIRYHGAPHIQSPVVHMSYIAANNLDVYAVILGTIVALCFITKLLFGLVVGKLRKNSRKAKVNQKHKLKKKQS", "length": 537 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VQT0-1", "protein_name": "UDP-glycosyltransferase family 36 member A1, isoform A", "gene_name": "Ugt36A1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTTCLRSGVLIIVLLGILGIPEPISAGNILAVYPHFGFSHFKVVMPILNELAHRGHDITVISYVKNPQAGAYPNYEELLISAPGEDQSSTTINLVPLTEHTPTRSLGVLIREYVDLHEEGQKTCEHLFASGHIERAIERHRNKPYDLLLTEYFNSDCQLALAKLLNLPIIGLSTCALMPYYYDRIDLPDTPAFIQSEFVGFAGQLNWHERLLNFVQAKLLKFLYKYHSNRADNELVRKYLGVEVDVEEVARTQTAFIFGNQHYSLMGSRPQSLQFVEIGGVHITKKAEQELPQNIANFLNQSAEGVIFISWGSMVRASSIDEDKLSAILEVLKSQPLKIIWKWEADETPDTDASKFLFVKWAPQLALLCHPKVKLFWSHGGLLGTTESVHCGKPLLVTPIYGDQFLNAFSVQNRGMGLKLDYQDITVPNLKKALAELSKNSYAQRSLEVSKVFNERQQTPLESAIWSVEHVISNGLIAARLLQSPGIELNGFVYHSLDSVALILLPLILLILVLCYLCKRNPSKLAHKKVGKKPKRS", "length": 537 }, "evidence": [ { "id": "MGI:2146055", "url": "https://alliancegenome.org/gene/MGI:2146055#orthology", "database": "AGR" }, { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080721-20", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080721-20#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060929-796", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-796#orthology", "database": "AGR" }, { "id": "SGD:S000004179", "url": "https://alliancegenome.org/gene/SGD:S000004179#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" }, { "id": "RGD:708541", "url": "https://alliancegenome.org/gene/RGD:708541#orthology", "database": "AGR" }, { "id": "RGD:628623", "url": "https://alliancegenome.org/gene/RGD:628623#orthology", "database": "AGR" }, { "id": "RGD:620895", "url": "https://alliancegenome.org/gene/RGD:620895#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VVW2-1", "protein_name": "UDP-glycosyltransferase family 316 member A1, isoform B", "gene_name": "Ugt316A1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MQILQVFLGTLLCGIVLGANVLTVFPSVWKSHYLFGRRLLQELVESSGNHSVTLISPHAAQEGVDAEIPKIRELRIEGLRENWLDMGMSFEAEEMRAQSVMERFTRLIYAGTTNVDILLSDPQVRKLLTSGEKFDLLIVDLFLSDALLGLAFYYGIPTVAVSPTGANSWLNNMFGNPQSSSLDPSNFLPFTERMNTRQRILNSLMSTFERLTYNFFHLISQQSVYTNHFELLVKELPLYRDLTKNLSLALINSHPGLHYPRAYLPNMVEVGGLHLSHLNDDNLPKHLLSFMESAPSGVIYFSLGADVETAQLPQEKLAIILDVFGHLKEFHFLLKWEKEEFTAEQVLPENVMIADWWPQQAILHHPQVKMFISSCGQLSVWESISGQKPVLAIPILAEQEVMAKRLQRHGVSVTVGYDSLAYDSLLHGIRQLTLNTSYVEKLGQLKERLISRDSTPVGKAVRKIQLILESGGADFLKSHANTLNFWRAEGVDVLLIIAVGFFGILTIPFLAICFILRKSYHSQAAQDQPPYRTNLKVVGRVHSYGDQGSSRSPKGTESLRRTRSAQSLSARSSSSSMSSNSPTSPSTASTTPLDLTPPPPIQLLGQVPPLQLYVNQQRIYSSDRKTSQEEAERRFS", "length": 636 }, "evidence": [ { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W2J4-1", "protein_name": "UDP-glucuronosyltransferase", "gene_name": "Ugt49B1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSLKSALHIFLLSLVALQQLELGTGSRILAAFFFPGKSHFMMTNAIIRELVKQGHEVTFITPFSLAKEKLGSNYKEIVIPQYDFWPEIKEMTNKNTVLEMTDLPTFAFLRMVNVMGIHTTDFALEQPEIQAVINEKNKIGKYDLLLAEQFFNEGALILGHLYQIPTITISTFGNANHLSQLFGVVSPWSYVPHAYMPYTDRMTLWERIGNVAMSAAEDLVREFSYYPGQDAVLKKHFSKLLDRVPTIKELERNISAILLNSYMPLASSRPMAYNMIPVGGLHIQPPKALPEHLQKFLDGATHGAIYFSLGSQVRSADLPPEKLKVFLEVFGSLKQRVLWKFEDESLPNLPANVKVQSWLPQGDILAHPNVKVFIAHGGLFGTQEAVYNGVPILGMPVYCDQHQNINQGKSAEYALGLDYRKVTVEELRGLLMELIENPKYRNNIKKASRIFRDRPLGAMDTAIYWINYVIEHRGAPHLVAAGVHLPWYQFYLLDIVGLGLAVILLPIVVLILICRRSSKPKSTPTKKKTKKN", "length": 532 }, "evidence": [ { "id": "MGI:2146055", "url": "https://alliancegenome.org/gene/MGI:2146055#orthology", "database": "AGR" }, { "id": "HGNC:12553", "url": "https://alliancegenome.org/gene/HGNC:12553#orthology", "database": "AGR" }, { "id": "HGNC:12542", "url": "https://alliancegenome.org/gene/HGNC:12542#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080721-20", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080721-20#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100402-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100402-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060929-796", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-796#orthology", "database": "AGR" }, { "id": "SGD:S000004179", "url": "https://alliancegenome.org/gene/SGD:S000004179#orthology", "database": "AGR" }, { "id": "RGD:69432", "url": "https://alliancegenome.org/gene/RGD:69432#orthology", "database": "AGR" }, { "id": "RGD:708541", "url": "https://alliancegenome.org/gene/RGD:708541#orthology", "database": "AGR" }, { "id": "HGNC:28183", "url": "https://alliancegenome.org/gene/HGNC:28183#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061103-373", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061103-373#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100406-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100406-3#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-23", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-23#orthology", "database": "AGR" }, { "id": "HGNC:12545", "url": "https://alliancegenome.org/gene/HGNC:12545#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "UDP-glycosyltransferase activity", "id": "GO:0008194", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008194", "evidence": [ { "database": "UniProtKB", "id": "Q9W2J3", "url": "https://www.uniprot.org/uniprotkb/Q9W2J3" } ], "pmid": "" }, { "name": "glucuronosyltransferase activity", "id": "GO:0015020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015020", "evidence": [ { "database": "UniProtKB", "id": "Q9W2J3", "url": "https://www.uniprot.org/uniprotkb/Q9W2J3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9W2J3", "url": "https://www.uniprot.org/uniprotkb/Q9W2J3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 437, "end_pos": 439, "annotation": "n_glycosylation_sequon" }, { "start_pos": 72, "end_pos": 74, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "21032", "name": "", "equation": "glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + UDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VDA5-1", "Q9VGT4-1", "Q9VGT5-1", "Q9VGS7-1", "Q9VJ46-1", "Q9VJ81-1", "Q9VGT2-1", "Q9VGT8-1", "Q9VJ45-1", "Q9W2J4-1", "Q9V9X9-1", "Q9VJ47-1", "Q9VGT0-1", "Q9W2J3-1" ], "evidence": [ { "id": "21032", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/21032" } ] }, { "id": "R-DME-158546", "name": "UGTs glucuronate APAP to APAP-GlcA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [ "R-ALL-9677362" ], "output_participant_list": [ "R-ALL-158604" ], "enzyme_list": [ "Q9V9X9-1", "Q9VJ47-1", "Q9VJ81-1", "Q9VGS7-1", "Q9VGT8-1", "Q9VDA5-1", "Q9VGT4-1", "Q9VJ45-1", "Q9VJ46-1", "Q9W2J4-1", "Q9VGT0-1", "Q9VGT2-1", "Q9VGT5-1", "Q9W2J3-1" ], "evidence": [ { "id": "R-DME-158546", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-158546" } ] }, { "id": "R-DME-6785933", "name": "UGT8 transfers Gal from UDP-Gal to CERA", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [ "R-ALL-428256", "R-ALL-1981137" ], "output_participant_list": [ "R-ALL-158602", "R-ALL-6785915" ], "enzyme_list": [ "Q9V9X9-1", "Q9VJ47-1", "Q9VJ81-1", "Q9VGS7-1", "Q9VGT8-1", "Q9VDA5-1", "Q9VGT4-1", "Q9VJ45-1", "Q9VJ46-1", "Q9W2J4-1", "Q9VGT0-1", "Q9VGT2-1", "Q9VGT5-1", "Q9W2J3-1" ], "evidence": [ { "id": "R-DME-6785933", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6785933" } ] }, { "id": "R-DME-9758661", "name": "UGT2B7,2B17,1A3 glucuronidates PRED metabolites", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9V9X9-1", "Q9VJ47-1", "Q9VJ81-1", "Q9VGS7-1", "Q9VGT8-1", "Q9VDA5-1", "Q9VGT4-1", "Q9VJ45-1", "Q9VJ46-1", "Q9W2J4-1", "Q9VGT0-1", "Q9VGT2-1", "Q9VGT5-1", "Q9W2J3-1" ], "evidence": [ { "id": "R-DME-9758661", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9758661" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-158602", "participant_name": "UDP [endoplasmic reticulum lumen]", "crossref": [ { "id": "58223", "database": "ChEBI", "url": "" }, { "id": "C00015", "database": "COMPOUND", "url": "" }, { "id": "ZINC000004490939", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-158604", "participant_name": "APAP-GlcA [endoplasmic reticulum lumen]", "crossref": [ { "id": "ZINC000005197198", "database": "ZINC", "url": "" }, { "id": "132962", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-1981137", "participant_name": "UDP-Gal [endoplasmic reticulum lumen]", "crossref": [ { "id": "66914", "database": "ChEBI", "url": "" }, { "id": "ZINC000008551104", "database": "ZINC", "url": "" }, { "id": "C00052", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-428256", "participant_name": "CERA [endoplasmic reticulum membrane]", "crossref": [ { "id": "83273", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-6785915", "participant_name": "GalCer [endoplasmic reticulum membrane]", "crossref": [ { "id": "36498", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-9677362", "participant_name": "APAP [cytosol]", "crossref": [ { "id": "5239", "database": "Guide to Pharmacology - Ligands", "url": "" }, { "id": "178101923", "database": "PubChem Compound", "url": "" }, { "id": "46195", "database": "ChEBI", "url": "" }, { "id": "W4WH4FK6P232", "database": "Pharos - Ligands", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "Q9V9X9", "gene_name": "Ugt35D1", "activity": [ { "ec_number": "2.4.1.17", "activity": "glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + UDP + H(+).", "evidence": [ { "id": "Q9V9X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9V9X9" } ] }, { "ec_number": "2.4.1.17", "activity": "", "evidence": [ { "id": "Q9V9X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9V9X9" } ] } ] }, { "uniprot_ac": "Q9VDA5", "gene_name": "Ugt49B2", "activity": [ { "ec_number": "2.4.1.17", "activity": "glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + UDP + H(+).", "evidence": [ { "id": "Q9VDA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VDA5" } ] }, { "ec_number": "2.4.1.17", "activity": "", "evidence": [ { "id": "Q9VDA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VDA5" } ] } ] }, { "uniprot_ac": "Q9VGS7", "gene_name": "Ugt303A1", "activity": [ { "ec_number": "2.4.1.17", "activity": "glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + UDP + H(+).", "evidence": [ { "id": "Q9VGS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VGS7" } ] }, { "ec_number": "2.4.1.17", "activity": "", "evidence": [ { "id": "Q9VGS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VGS7" } ] } ] }, { "uniprot_ac": "Q9VGT0", "gene_name": "Ugt35B1", "activity": [ { "ec_number": "2.4.1.17", "activity": "glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + UDP + H(+).", "evidence": [ { "id": "Q9VGT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VGT0" } ] }, { "ec_number": "2.4.1.17", "activity": "", "evidence": [ { "id": "Q9VGT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VGT0" } ] } ] }, { "uniprot_ac": "Q9VGT2", "gene_name": "Ugt35E1", "activity": [ { 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"id": "Q9VJ47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJ47" } ] }, { "ec_number": "2.4.1.17", "activity": "", "evidence": [ { "id": "Q9VJ47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJ47" } ] } ] }, { "uniprot_ac": "Q9VJ81", "gene_name": "Ugt301D1", "activity": [ { "ec_number": "2.4.1.17", "activity": "glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + UDP + H(+).", "evidence": [ { "id": "Q9VJ81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJ81" } ] }, { "ec_number": "2.4.1.17", "activity": "", "evidence": [ { "id": "Q9VJ81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VJ81" } ] } ] }, { "uniprot_ac": "Q9W2J3", "gene_name": "Ugt49C1", "activity": [ { "ec_number": "2.4.1.17", "activity": "glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + UDP + H(+).", "evidence": [ { "id": "Q9W2J3", "database": "UniProtKB", "url": 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"database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.17" }, { "id": "2.4.1.17", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.4.1.17" } ] } ], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 437, "end_pos": 439 }, { "start_pos": 72, "end_pos": 74 } ] }, "class_list": [ "glycogene", "glycosyltransferase" ], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { 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"https://www.ncbi.nlm.nih.gov/protein/NP_611561" }, "gene_names": [ { "name": "Lapsyn", "type": "recommended", "evidence": [ { "id": "Q9W2J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W2J7" } ] }, { "name": "CG15658", "type": "synonym", "evidence": [ { "id": "NP_611561", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611561" }, { "id": "Q9W2J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W2J7" } ] }, { "name": "CT35842", "type": "synonym", "evidence": [ { "id": "NP_611561", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611561" }, { "id": "Q9W2J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W2J7" } ] }, { "name": "Dmel\\CG15658", "type": "synonym", "evidence": [ { "id": "NP_611561", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611561" }, { "id": "Q9W2J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W2J7" } ] }, { "name": "Dmel_CG15658", "type": "synonym", "evidence": [ { "id": "Q9W2J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W2J7" } ] }, { "name": "Lapsyn", "type": "synonym", "evidence": [ { "id": "NP_611561", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611561" } ] } ], "protein_names": [ { "name": "CG15658-PA", "type": "synonym", "evidence": [ { "id": "NP_611561", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611561" } ] }, { "name": "Lapsyn-PA", "type": "synonym", "evidence": [ { "id": "NP_611561", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611561" } ] }, { "name": "Leucine-rich repeat activity-regulated protein at synapses", "type": "synonym", "evidence": [ { "id": "NP_611561", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611561" }, { "id": "Q9W2J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W2J7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W2J7", "url": "https://www.uniprot.org/uniprotkb/Q9W2J7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Lapsyn", "url": "https://www.uniprot.org/uniprotkb/Q9W2J7", "locus": { "chromosome": "2R", "start_pos": 21199431, "end_pos": 21193571, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0034602", "url": "https://www.ensemblgenomes.org/id/FBgn0034602" } ] } } ], "crossref": [ { "id": "FB:FBgn0034602", "url": "https://alliancegenome.org/gene/FB:FBgn0034602", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0034602", "url": "https://bgee.org/?page=gene&gene_id=FBgn0034602", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0034602", "url": "https://flybase.org/reports/FBgn0034602", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "37418", "url": "https://www.ncbi.nlm.nih.gov/gene/37418", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG15658", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG15658", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CGCQQVT", "url": "https://omabrowser.org/oma/group/CGCQQVT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W2J7", "url": "https://www.orthodb.org/?gene=Q9W2J7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45712", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45712", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45712:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45712:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q9W2J7", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q9W2J7", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_611561", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611561", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W2J7", "url": "https://www.uniprot.org/uniprotkb/Q9W2J7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W2J7-1", "url": "https://www.uniprot.org/uniprotkb/Q9W2J7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELHWQLLTFIVCLQLLHSAGFIIQSEVRKCTYGHIDKLLRIRCYDLDLKEVPQNLKSSVEVLDLSHNRIRKLKTSSFQRYTDIKFLMLYDNMILSVEVGTFEPLTSLQEIDLSNNGLTTIPLELFQLPRLRNLYIDSNELTSLNLQALEKPIRAPLEYLNVAGCELQELPDLGILPKLWQLNASMNPLQNFRIDSLANMCHLQVIDLTKSQLSQCGCQQVTNHLMMLGASPKFVPVCLEALDIRECPLPYNRTIHSPTFASCQTTLQFAETRSFWLFGAGCFGGVCFVLLIVIFCVIHCRRKRAQRRKRNAQKRKPFVISPRNAINNRQPEDEPLHCDIARK", "length": 343, "header": "tr|Q9W2J7-1|Q9W2J7_DROME Isoform 1 of Leucine-rich repeat activity-regulated protein at synapses OS=Drosophila melanogaster OX=7227 GN=Lapsyn PE=4 SV=2 CANONICAL=Q9W2J7-1" }, "isoforms": [ { "isoform_ac": "Q9W2J7-1", "url": "https://www.uniprot.org/uniprotkb/Q9W2J7/entry#Q9W2J7-1", "sequence": { "sequence": "MELHWQLLTFIVCLQLLHSAGFIIQSEVRKCTYGHIDKLLRIRCYDLDLKEVPQNLKSSVEVLDLSHNRIRKLKTSSFQRYTDIKFLMLYDNMILSVEVGTFEPLTSLQEIDLSNNGLTTIPLELFQLPRLRNLYIDSNELTSLNLQALEKPIRAPLEYLNVAGCELQELPDLGILPKLWQLNASMNPLQNFRIDSLANMCHLQVIDLTKSQLSQCGCQQVTNHLMMLGASPKFVPVCLEALDIRECPLPYNRTIHSPTFASCQTTLQFAETRSFWLFGAGCFGGVCFVLLIVIFCVIHCRRKRAQRRKRNAQKRKPFVISPRNAINNRQPEDEPLHCDIARK", "length": 343, "header": "tr|Q9W2J7-1|Q9W2J7_DROME Isoform 1 of Leucine-rich repeat activity-regulated protein at synapses OS=Drosophila melanogaster OX=7227 GN=Lapsyn PE=4 SV=2 CANONICAL=Q9W2J7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W2J7", "url": "https://www.uniprot.org/uniprotkb/Q9W2J7" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W2J7", "url": "https://www.uniprot.org/uniprotkb/Q9W2J7" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2J7", "url": "https://www.uniprot.org/uniprotkb/Q9W2J7" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2J7", "url": "https://www.uniprot.org/uniprotkb/Q9W2J7" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W2J7", "url": "https://www.uniprot.org/uniprotkb/Q9W2J7" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W2J7", "url": "https://www.uniprot.org/uniprotkb/Q9W2J7" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W2J7", "url": "https://www.uniprot.org/uniprotkb/Q9W2J7" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2J7", "url": "https://www.uniprot.org/uniprotkb/Q9W2J7" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2J7", "url": "https://www.uniprot.org/uniprotkb/Q9W2J7" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W2J7", "url": "https://www.uniprot.org/uniprotkb/Q9W2J7" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W2J7", "url": "https://www.uniprot.org/uniprotkb/Q9W2J7" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG15658", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG15658", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0B4KHL5-1", "protein_name": "Kekkon 6, isoform B", "gene_name": "kek6", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MHRSMDRRRSRTPRTLPVCWILLCLVAWTVADDWSLSCASNCTCKWTNGKKSAICSSLQLTTIPNTLSTELQVLVLNDNHIPYLNREEFSTLGLLNLQRIYLKKSEVQYIHKESFRNLKILVEIDLSDNKLEMLDKDTFMGNDRLRILYLNGNPLKRLAAYQFPILPHLRTLDMHDCLISYIDPMSLANLNLLEFLNLKNNLLESLSEYVFQHMANLKTLSLEENPWQCNCKLRKFRGWYVNSRLSSVSLVCKGPPAQKDRTWDSVDDELFGCPPRVEIFNNEEVQNIDIGSNTTFSCLVYGDPLPEVAWELNGKILDNDNVLFESESIASDKLWSNLTVFNVTSLDAGTYACTGSNSIGSMTQNISIYLSEIVQHVLEKTPETFWYFGLIMGIFGTVFLLISISFVVCLCKRTTRQHRHANKAGVKSSVSFNDQEKKLLDSSVTTTTNDRGDSYGIDNQPTSIGMNKGDSAGMGFNQIEIHAVESHRHGSMLVQQQPQQQQVAGGGGMRQQLMQVKDSTCGMMSVPTSMAGHAHSHPAQISEEFPLNVGVFPPPPEFCSNIVPNPAFGGNIFIRVSVTQDMLDGADLNMYPDLLNIPKRMQDVQESGAGAVAVPEGQFATLPRHTARRGILKKDTSLQQQQQQHQQQHQHQQQQQQQQIQQQQHQQLQQQHQPSGLYTHDEIVTYNLEASGYDPHQSGYHSNAMELPPPPPPPAVTAVVQCHHPSPNNCASCINNAPPPPSACQSPPVEVTPMRPLDSSAYPKYDNMGRRITASGGLGGSNLSLHDEERYENETLFGQAESQTKGMPEQSQDLHQPQEVTQGQDKGGGPGEFVSLXYYGTQV", "length": 843 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080327-11", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080327-11#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A0A4D6K327-1", "protein_name": "Hattifattener, isoform I", "gene_name": "haf", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRPGRTTTALPAATTPLLLLLPLILGRLHVAHAQCPWQRDVPDLQTSCICAYNLGRELSVQCDQVDFSQLLAAMNTHARLKPVDLLYVNNSTISELPDAVFSNLSLHNLQLSSCGIQRIATGAFKGQESVLRNLNLQDNLLADVPVEALKVLGKLNLLDLSKNQLSHIPDDAFVGLTKLSTLKLNDNNVTLASNAFRGLEQSLKNLNLKGTKQRKVPESIRGLKSLAFLDLSQNGIKELPGAGGIRVFDGLDALTALNLERNLIQSIGETAFAGVRKTLSSLSLLNNLLAEFPIGAVHSLKELRVLDIGFNLLTSLPEAAFRGNPGITLLALDGNPLSSVPEGAFAHLNATLRGLSLGGRFLHCDCKLRWVAEWIRNGDLQVTSRERNPQFCGTPPRFRDRGFYSIQPEELSCPDIADAALRGPVGLADNLKPTLPSSPDSVEYETGTGTGTVGTGTAASAPVTSSVSSSTSTTTPTTTTTTTTAEPTTRRSTTRPPTKSTTTISATTASPASNPPVNGTGTVQATSITTSSSSSSSSSTSTGHGNGKQAPGWRQGVTNGNGNSGVGGAGGLHKPQRPPLVLGYPPQRGTRIDDANEVQVKHAFRQDSSVIIQWDSDTANILGFRVVYRLFGEKAFKQGPPLESSEREFKIKNVPAQECIIVCVISLEELHVTPETVPYQQCREVRTVASQASNMDKITIAASAAICGTIIVAVIVFIAASRRSRKLQSSQQKSPLPIGGLPVNCCGPTGSPGPLGSIATLSAFNNHKEWDQVSAYSGRSIPRPRIYPVEQPDDMRSHFSGMPGKVGKSRSLADGQSQHSFSNNSHRGYLGSAFPSNLVNSRPELRQSRQSLAAASERMSRASYAGSIHGGNGGGGGLGGNGGGGGNGLPVSSLMAMSGMVGGGGPASIASSARRSRPRSRSREQLNTTHIHNHRPGSRYSQAGSTHTLNNYCDTSDNWTDHDMDIYMARNPTTRNGLVPLXGRLTLSXYFNVVLNWDGIFXQYLTPTIEGTEGRGRGRRQQQQQQQQQQQQQQQHQQLQHQQQQQHQHQLQQLRNERHQQRHRNDQQWEQPYQPAQQQHQRLQYYMPQTERCTSPPDVVPRAANFHNSNTTSTGHNDNSNSHGSSSSSSSNIAQQQQAPLAAMTAALGDATAAATAAAAAAASASGIVVENYFNEYERQEIIYHHPTSRRSSSSSSSCSAAATRHVPRSNAFRLQLPAVATATTNNILYNISNKHGATGHNGSIGNYKAHTFSDSCNCTCNCSLSEEEEISQETAAVTAAAGEDGDQAGSSLSSTSVSSIEQVQQGQQEQQGQEVYLSLNLTLADAAAGADAAADAADASADRAEL", "length": 1347 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080327-11", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080327-11#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A0A6M3Q7U5-1", "protein_name": "Fish-lips, isoform E", "gene_name": "Fili", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPDHTRVTATTRSRPWLCGAIPVLLLLLLTLVILPPETTAFCPSKCQCLGGEANSRALCVDAALEDVPIQLNPETKYINLTVNRIRTLEFSLPFYMKLEILDLSQNIIETLGSKNFEYQSELRTLNLSRNLVSSLHKHAFKGLTNLLLLDLSFNRIETVHPTALSDLASLVELDLTNNNIVSLEDNCFKGMNTLEVLVFRNNRLLDVPASNLWHLHALKSLDMSLNLVEFVRNDSFEGLKELLALSVQGNVMSELDLSAFEGLISLKHLDLSDNNLTMVPTQQLSKLSNLTYLNLGGNRFSQLPAVAFLNLFHLRELHLSRLDFLQRIDSRAFVDNTHLQTLHLNNNPQLSDIPMRLFQGNPNILEVYMQSNSLQTLYSAQFPVDQLQKLYLGDNPLQCNCSLLWLWRLVTGNFEGVDPGMEHAAGGAVAALAKEADDEELADEATAVASTDDGVAALAAYIAEQHIVNALHTTEPSAYELATSSSNRNSGILRMDRQQIGCDIWRDKVRTRRKLLTMSEGEITCPAHIVTVVCAVITCLLVAMIGISVLYYLRFVKRRRKLLHERGPMRTSKSIINVHDRILQGHNPGGLGLGMSMTLGGGNHVNGLGMTLNYPHHAQTLQAHHHYHQAMPLQSHGGNGNHEYQQTTLPQLDKLELERYLAAQTIANEYRALKPWELPVKEADDEPEHLYERFDHYEYPDTHTMSKLKQAASLNHSNSSAGPSPVPPSSGKPHVVYVXRGRGTGERVSQINTDIEMVGLNHLHLHHHHHNNNNNYRGCVQSAKASGQF", "length": 789 }, "evidence": [ { "id": "MGI:2443855", "url": "https://alliancegenome.org/gene/MGI:2443855#orthology", "database": "AGR" }, { "id": "RGD:1359311", "url": "https://alliancegenome.org/gene/RGD:1359311#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A0ABK0LGB6-1", "protein_name": "Leucine rich repeat containing 3C", "gene_name": "Lrrc3c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWALRECQPEPLVFAWLPWQSYRFSSSPGLCLSATMLLLAPRLLPLLLVIGTGRSVSSPQTLPQGCYIAEEAGEQTFRCSRAGLSAVPSGIPNDTRKLYLDANQLASVPAGAFQHLPALEELDLSHNVLVHLSGAAFQGLEATLRHLDLSANQLASVPVAAFVGLQIQVNLSANPWRCDCALQEVLRHVRLAPGSGTGIVCGPEARPDLVGHEFLLLTGEEELCGTGRGGTRRSTDVALLVTMGGWLTLVVAYLIHYVWQNRDETRHPVKRAPPVQPVRSEDSSTLSTVL", "length": 290 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080327-11", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080327-11#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AC58I9N7-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "lrrc3cb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMGCHPMASCLSLTLTLFLYQLDVCVSDSHHEECPESCFCTEGINSGLVVHCSSMHLTAVPRDLPNTTQHLYLDNNLLLTIPSDAFKGLPLLFKLDLSHNRLVGLEHGAFRDLADSLRSLDLSSNLLETLDPGAFGDLRAQTNLSQNRWLCDCRLQLAMPQLLLDPSSLAEVMCNSSEPQELGAQGLPFILVATDLDFCATIRRTTDVAMLITMFGWFTMVISYLVYYIRHNQEDAIRHLEYLKSLPNRQGSLFINLGSQQRNEPPTYPAYVLSSGCPSSCNPLLKEEMHSSEPLEFSSTTHHSFNPSPHEPEVPSDIYQSPLKLHSDARFYSQPISELDFLPLCF", "length": 346 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080327-11", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080327-11#orthology", "database": "AGR" }, { "id": "FB:FBgn0034602", "url": "https://alliancegenome.org/gene/FB:FBgn0034602#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A6NJW4-1", "protein_name": "Leucine-rich repeat-containing protein 3C", "gene_name": "LRRC3C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRMTSSSFVSYCTPGLCQFMAMLPTAGHLLPLLLVIGTGGTVPSPQVPPRGCYVAKEAGERTFRCSQAGLSAVPSGIPNDTRKLYLDANQLASVPAGAFQHLPVLEELDLSHNALAHLSGAAFQGLEGTLRHLDLSANQLASVPVEAFVGLQIQVNLSANPWHCDCALQEVLRQVRLVPGTGTGIVCGSGARPDLVGQEFLLLAGEEELCGSGWGGARRSTDVALLVTMGGWLTLMVAYLVHYVWQNRDETRRSLKRAPVLPVRSEDSSILSTVV", "length": 275 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080327-11", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080327-11#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q58A48-1", "protein_name": "Tsukushi", "gene_name": "tsku", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASLLCLFFSLLGLAAIGAVKNCHPQCRCEVETFGLFDSFSLTKVDCSRIGPGNTPVPIPLDTSHLDLSLNSTTSISDTMLSGPGYTTLVSLDLSSNLIAQISPKAFSKLRYLETLDLSSNALEGLSDGCFTGLPLVELDLSENQFKEFNLDLFTTRTQDLPIMVDLSRNLLTSIFRRTPGHPLYIKSLMLAGNQLKTVPKLNGIPLQYLNLDGNLISSIDTGAFDSLTELVHLSLSGLSELTLIHPGAFRSLKNLQALDLSNNSQLKTLNPNVFSGLVSLQELNLSNTAVTPLSRTVFMQMPNIKSITLGPNVHCWKTHMQGQFHRQIGQAKPNDILTCDNAGLIL", "length": 347 }, "evidence": [ { "id": "MGI:2443855", "url": "https://alliancegenome.org/gene/MGI:2443855#orthology", "database": "AGR" }, { "id": "RGD:1359311", "url": "https://alliancegenome.org/gene/RGD:1359311#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6QMY6-1", "protein_name": "Tsukushi", "gene_name": "Tsku", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLCTLFLLLLALGIVQTTRPCFPGCQCEEETFGLFDSFSLIRVDCSSLGPHIVPVPIPLDTAHLDLSSNRLETVNESVLGGPGYTTLAGLDLSHNLLTSITPTAFSRLRYLESLDLSHNGLAALPAEVFTSSPLSDINLSHNRLREVSISAFTTHSQGRALHVDLSHNLIHRLLPYPARASLSAPTIQSLNLSWNRLRAVPDLRDLPLRYLSLDGNPLATINPGAFMGLAGLTHLSLASLQGILQLPPHGFRELPGLQVLDLSGNPKLKWAGAEVFSGLGLLQELDLSGSSLVPLPETLLHHLPALQSVSVGQDVQCRRLVREGAYHRQPGSSPKVVLHCGDTQESARGPDIL", "length": 353 }, "evidence": [ { "id": "MGI:2443855", "url": "https://alliancegenome.org/gene/MGI:2443855#orthology", "database": "AGR" }, { "id": "RGD:1359311", "url": "https://alliancegenome.org/gene/RGD:1359311#orthology", "database": "AGR" }, { "id": "FB:FBgn0034602", "url": "https://alliancegenome.org/gene/FB:FBgn0034602#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8CBR6-1", "protein_name": "Tsukushi", "gene_name": "Tsku", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLCSLFLLLLAVGRVQTTRPCFPGCQCEEETFGLFDSFSLIRVDCSSLGPHIVPVPIPLDTAHLDLSSNRLETVNESVLAGPGYTTLAGLDLSYNLLTSIMPSAFSRLRYLESLDLSHNGLAALPAEIFTSSPLSDINLSHNRLREVSISAFTTHSQGRALHVDLSHNLIHRLLPHPARASLPAPTIQSLNLSWNRFRAVPDLRDLPLRYLSLDGNPLATINPDAFMGLAGLTHLSLASLQGILHLPPHGFRELPGLQVLDLSGNPKLKWAGAEVFSGLGLLQELDLSGSSLVPLPEMLLHHLPALQSVSVGQDVQCRRLVREGAYHRQPGSSPKVVLHCGDTQESAARGPDIL", "length": 354 }, "evidence": [ { "id": "MGI:2443855", "url": "https://alliancegenome.org/gene/MGI:2443855#orthology", "database": "AGR" }, { "id": "RGD:1359311", "url": "https://alliancegenome.org/gene/RGD:1359311#orthology", "database": "AGR" }, { "id": "FB:FBgn0034602", "url": "https://alliancegenome.org/gene/FB:FBgn0034602#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WUA8-1", "protein_name": "Tsukushi", "gene_name": "TSKU", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPWPLLLLLAVSGAQTTRPCFPGCQCEVETFGLFDSFSLTRVDCSGLGPHIMPVPIPLDTAHLDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGLTALPAESFTSSPLSDVNLSHNQLREVSVSAFTTHSQGRALHVDLSHNLIHRLVPHPTRAGLPAPTIQSLNLAWNRLHAVPNLRDLPLRYLSLDGNPLAVIGPGAFAGLGGLTHLSLASLQRLPELAPSGFRELPGLQVLDLSGNPKLNWAGAEVFSGLSSLQELDLSGTNLVPLPEALLLHLPALQSVSVGQDVRCRRLVREGTYPRRPGSSPKVALHCVDTRDSAARGPTIL", "length": 353 }, "evidence": [ { "id": "MGI:2443855", "url": "https://alliancegenome.org/gene/MGI:2443855#orthology", "database": "AGR" }, { "id": "RGD:1359311", "url": "https://alliancegenome.org/gene/RGD:1359311#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VK28-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CT35580", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEAISKISLILCALFVGLKAAAAISGDSTHCLATYSSAEAYLAQIPQQHRPQIRPRIRTWQEHEFSLLGYKFHLPFVGHAVDSDLDDSDSDEGLWLDAADAGSESVEVEEHELPSVGHVDPTGNVFKLNCEHVDLRRVNQELLSQRSSHINYNQLMLAHVPADRSNPLKLPQLESLREFSWQSSELKDETLMELFTRQPRSFEYMERLNLAENRLECLHWAIPLAVRRVKVLEMSGNRLSNCSLLNLQYMKQLQELHLDRSELTYLPQRFLGELSELRMLNLSQNLLTELPRDIFVGALKLERLYLSGNRLSVLPFMLFQTAADLQVLDLSDNRLLSFPDNFFARNGQLRQLHLQRNQLKSIGKHSLYSLRELRQLDLSQNSLSVIDRKAFESLDHLLALNVSGNNLTLLSSIIFQSLHALRQLDLSRNQFKQLPSGLFQRQRSLVLLRIDETPIEQFSNWISRYDESLVDPQVLHRLRYLSVQQNRKLTYLPATLFANTPNIRELLLAENGLLQLPTQISGLSRLQRLSVRGNSLGSLPENIKELRQLHYLNILGNEYQCDCSMYWLTAWLANTSTSLRHQMPQAQNHSNGSTNQTPLDSYESIDHQIDALKCQYGYRGDMLRVLSKLNCSVPTVVQFSEPKMHKLLSTAKLECQISGSPVPDIIWVTPRNKILRHHADPDKRPIIIDSKEDAHQPPSAQELAALMDESYIQSLNWTRQNSLVGRRVVLVENGSLLVHNISRIDSGLYTCYAFNVMGKASAGLRLYIDPIVFYRVKIGSILFGTALATAFLLLTLIVQGLRSCLSRWGICNRFYCCVNRKKKSPRKHQIYAMLDSIETYKSQQLERLRENYTQQVHRIRENCAQQVEWIQSSYTSQAKHIREFRDIGSNHLTTLKDQYYDQVKKVRDYSTGQLSWVRENYVFQRNKIRKFSAHQVLRLREGYKYQQQTLNKVLENLPSFYFENCRGRCEEDIAEDIDCYFKGQMDFGDSKELHIQKIKARLSANYSASKASLYYTPPDDDLLHSSQLNLQNSPIHINYIDENLDQQKQLEHDFKMEPQLLLYNASMLYMNPEGASSSGQAAALAAAGALSQFISVEDNNQEQEMQPLRKISGKPLGMPELKDLNDVKTSKSCPAIYKVSKQRDGSTLHELQKEGEAPYQMLRINPVETTSLTSTVAPVMQARTEKLNIILDECGTASLCKAEQEGDAGNSETPPSESSCESNSLAASCGDVCQVSSKLANDASLPSTPPKPDHAST", "length": 1257 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080327-11", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080327-11#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VS84-1", "protein_name": "Larval translucida, isoform B", "gene_name": "ltl", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTSLVYTVFHLASLQCSVRPEISPCTCETGKAWNHVELSCEKLESFNAVVDSLANKLNADTNIDLKITHSQLDDLEMRSFTDMNFNLYKLRMQWNSLKSLPEVPFRGLSNVTYLSIGDNDLDEIPKHALSHMPSLLTLDIGRCKIRAVQQEDFRGIQRVTNLILVSNIITRLDRGSFPKSLLILHLGRNQLESLNGSLHDLHNLESLFINANNITSLDDELPDGGQLRLLMAHNNRLERLPANMAGMHSLETVHIHCNQLRSFDRVLRNAVNLSEVMADNNELEYLAQDEFASCSKVETLQMGCNHIKSLNSSLLPILKLKNANFSFNDIEEFSMAELHGLRSLKTLQLSSNRIQRLLPDPRGVQELMLVNLDLDNNRIDSLNGALAGLGNLRILNLAGNRLEHLQVGDFDGMIRLDILDLTGNQLAELKPLEMTLLPSLKILKVAYNNITKLEQDFKGLPVLCQANLTNNQISTISSELVTNTRCKNHNVPGKLEIHLDDNPIMCDVGLNELCRLMAVQEARIRGRSQCFENDQEVCTVLPMLYNVNLPIMVTNLKLTGREVPKPMVRVIVPSLIKANNELLPPLIATLGNPVLISTDLVNPVISPLPPPLLLATTTPPPPLPLPVESEVEKNESTTANPVPTNYTQETTTTTSTTTTTTTTETSSQVAPIEIITTTAPTTTTTSTTTPKPNETLPVIVELQDPNPPDTTVNQTALVPPVVLDPLQQDLERERERERERELERDLDHEAVAKTEYETVEYIPNLVQPPVGSDALTPPPSKANALEEDSESVHSNSVHAEYPHAAQSLQIPEEPPEE", "length": 817 }, "evidence": [ { "id": "MGI:2443855", "url": "https://alliancegenome.org/gene/MGI:2443855#orthology", "database": "AGR" }, { "id": "RGD:1359311", "url": "https://alliancegenome.org/gene/RGD:1359311#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "X2J6K6-1", "protein_name": "Reduced ocelli, isoform B", "gene_name": "rdo", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLFKWLLFSLCIMPAMFSNTKRKCPTECQCSMDDLDRYQAICTKGGLNSLLSPNELDVDVKVIIIRGPRNSITIGPALRQFMKLEILRITDSNLPAIGAESFWGLKYLRILDLSKNNITNITENNFRGQDNLLELDLSKNKVLRMASSTFRHLTDLRRLNLADNSIVELVQRNFFMLSRLKYLDLSGNPLQDLQPDVFRDVPELKVLKCRNCQLKKINPQMYNLLPLLSELDLGRNEFKFLDKDEFRDVKRLTKVLLDGNQLSVVVDQLFRMQKSLNHLDLSYNRLAKVPNDSFLQLTNLTFLDLSYNKLVRLEPQSIRSLSNLLTLNISGNVLMDLREMRETFEPLIYYFFLTCSKLFFQLIPQLTHLAIADMGTMPVGLLHPFKQLRYLNISGNSLNNTALEVIDPCRELEFLDLSRNQLHGISEDTVLRIQGIRNVRLDNNPLICDECHMGKLINVVRQLQWKWDTYPICFLPKSLRGAEINNLDINGLHTCLTFITDEEQNAASTSYNFLEHGGLNTLAILGGIIFVLIAVIILSLVACFSKNRARYYTREDHLNGSESKCLEKNLEATTITTLGNGSSPTTTTTLTLATSPAAPNGPKTNGQGLSLSPANGSTPVHGISDDKGKEINFTFPVDDRVCTIDELMPSPPPPPQQHPHPNMGSLMYSVSHSPNSATTLAAVAAAATVIPPGAPSHSSMPTPTPTPAEAVVVVLPPPPLPPQQHHHQMDGSLASLREVQQQLVHLSSTLEPLVSVN", "length": 757 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080327-11", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080327-11#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "Q9W2J7", "url": "https://www.uniprot.org/uniprotkb/Q9W2J7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "Q9W2J7", "url": "https://www.uniprot.org/uniprotkb/Q9W2J7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 183, "end_pos": 185, "annotation": "n_glycosylation_sequon" }, { "start_pos": 252, "end_pos": 254, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 183, "end_pos": 185 }, { "start_pos": 252, "end_pos": 254 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9W2K8-1", "uniprot_ac": "Q9W2K8", "uniprot_id": "Q9W2K8_DROME", "mass": { "chemical_mass": 41694.0, "monoisotopic_mass": 41694.0 }, "refseq": { "ac": "NP_611553", "name": "high mobility group protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611553" }, "gene_names": [ { "name": "Hmg-2", "type": "recommended", "evidence": [ { "id": "Q9W2K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W2K8" } ] }, { "name": "BEST:LD07122", "type": "synonym", "evidence": [ { "id": "NP_611553", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611553" }, { "id": "Q9W2K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W2K8" } ] }, { "name": "CG9418", "type": "synonym", "evidence": [ { "id": "NP_611553", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611553" }, { "id": "Q9W2K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W2K8" } ] }, { "name": "Dmel\\CG9418", "type": "synonym", "evidence": [ { "id": "NP_611553", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611553" }, { "id": "Q9W2K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W2K8" } ] }, { "name": "Dmel_CG9418", "type": "synonym", "evidence": [ { "id": "Q9W2K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W2K8" } ] }, { "name": "Hmg-2", "type": "synonym", "evidence": [ { "id": "NP_611553", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611553" } ] }, { "name": "LD07122", "type": "synonym", "evidence": [ { "id": "NP_611553", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611553" }, { "id": "Q9W2K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W2K8" } ] } ], "protein_names": [ { "name": "CG9418-PA", "type": "synonym", "evidence": [ { "id": "NP_611553", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611553" } ] }, { "name": "High mobility group protein 2", "type": "synonym", "evidence": [ { "id": "Q9W2K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W2K8/entry#names_and_taxonomy" } ] }, { "name": "Hmg-2-PA", "type": "synonym", "evidence": [ { "id": "NP_611553", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611553" } ] }, { "name": "high mobility group protein 1/2", "type": "synonym", "evidence": [ { "id": "NP_611553", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611553" } ] }, { "name": "high mobility group protein 2", "type": "synonym", "evidence": [ { "id": "NP_611553", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611553" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W2K8", "url": "https://www.uniprot.org/uniprotkb/Q9W2K8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Hmg-2", "url": "https://www.uniprot.org/uniprotkb/Q9W2K8", "locus": { "chromosome": "2R", "start_pos": 21147608, "end_pos": 21146203, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0026582", "url": "https://www.ensemblgenomes.org/id/FBgn0026582" } ] } } ], "crossref": [ { "id": "FB:FBgn0026582", "url": "https://alliancegenome.org/gene/FB:FBgn0026582", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0026582", "url": "https://bgee.org/?page=gene&gene_id=FBgn0026582", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd21980", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21980", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0026582", "url": "https://flybase.org/reports/FBgn0026582", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "37407", "url": "https://www.ncbi.nlm.nih.gov/gene/37407", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036910", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036910", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG9418", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG9418", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IFTHEFL", "url": "https://omabrowser.org/oma/group/IFTHEFL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W2K8", "url": "https://www.orthodb.org/?gene=Q9W2K8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46040", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46040", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46040:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46040:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00505", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00505", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-3214815", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-3214815", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-983231", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-983231", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_611553", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611553", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W2K8", "url": "https://www.uniprot.org/uniprotkb/Q9W2K8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W2K8-1", "url": "https://www.uniprot.org/uniprotkb/Q9W2K8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTEPTSKTPDAVPESPVSLPIASQSMDTATIEDFDEDKPAKGKKKAKNPKGRHSDSDIGSELKKLAQRRINVAGAPKMPLNGYVRFMNDRREELRREQPQRTALEHTRIIGEEWHQLPEERKLPYIEAAAKDKAIYQEQLQMFLKEHPEIVANELAKAKKATKLDGSPKEKTPKGESALGKAKKTKAKPVKRQSEDPDDVPLAKVKRAQTPPPPTPPAAPVQPPPSSVPPATPAPRPLQPGEIPIYTNEFIEHNRSTENELRTLRKAKTDLEQQNAVLEQHVDNTKAGYAKVMGEVTELMEENQRLETYLRALRQKLVAALGGISMPPLEPSGPSVGNIDKYIRHLAGLVTQPSNVTLIKAREALRKVDTSSLLKP", "length": 376, "header": "tr|Q9W2K8-1|Q9W2K8_DROME Isoform 1 of High mobility group protein 2 OS=Drosophila melanogaster OX=7227 GN=Hmg-2 PE=4 SV=1 CANONICAL=Q9W2K8-1" }, "isoforms": [ { "isoform_ac": "Q9W2K8-1", "url": "https://www.uniprot.org/uniprotkb/Q9W2K8/entry#Q9W2K8-1", "sequence": { "sequence": "MTEPTSKTPDAVPESPVSLPIASQSMDTATIEDFDEDKPAKGKKKAKNPKGRHSDSDIGSELKKLAQRRINVAGAPKMPLNGYVRFMNDRREELRREQPQRTALEHTRIIGEEWHQLPEERKLPYIEAAAKDKAIYQEQLQMFLKEHPEIVANELAKAKKATKLDGSPKEKTPKGESALGKAKKTKAKPVKRQSEDPDDVPLAKVKRAQTPPPPTPPAAPVQPPPSSVPPATPAPRPLQPGEIPIYTNEFIEHNRSTENELRTLRKAKTDLEQQNAVLEQHVDNTKAGYAKVMGEVTELMEENQRLETYLRALRQKLVAALGGISMPPLEPSGPSVGNIDKYIRHLAGLVTQPSNVTLIKAREALRKVDTSSLLKP", "length": 376, "header": "tr|Q9W2K8-1|Q9W2K8_DROME Isoform 1 of High mobility group protein 2 OS=Drosophila melanogaster OX=7227 GN=Hmg-2 PE=4 SV=1 CANONICAL=Q9W2K8-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 215, "start_aa": "Thr", "end_pos": 215, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr215", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 232, "start_aa": "Thr", "end_pos": 232, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr232", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W2K8", "url": "https://www.uniprot.org/uniprotkb/Q9W2K8" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W2K8", "url": "https://www.uniprot.org/uniprotkb/Q9W2K8" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2K8", "url": "https://www.uniprot.org/uniprotkb/Q9W2K8" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2K8", "url": "https://www.uniprot.org/uniprotkb/Q9W2K8" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W2K8", "url": "https://www.uniprot.org/uniprotkb/Q9W2K8" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W2K8", "url": "https://www.uniprot.org/uniprotkb/Q9W2K8" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W2K8", "url": "https://www.uniprot.org/uniprotkb/Q9W2K8" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2K8", "url": "https://www.uniprot.org/uniprotkb/Q9W2K8" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2K8", "url": "https://www.uniprot.org/uniprotkb/Q9W2K8" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W2K8", "url": "https://www.uniprot.org/uniprotkb/Q9W2K8" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W2K8", "url": "https://www.uniprot.org/uniprotkb/Q9W2K8" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG9418", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG9418", "resource": "KEGG Pathway" }, { "id": "R-DME-3214815", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-3214815", "resource": "Reactome", "description": "HDACs deacetylate histones" }, { "id": "R-DME-983231", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-983231", "resource": "Reactome", "description": "Factors involved in megakaryocyte development and platelet production" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1MNU6-1", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related", "gene_name": "LOC533921", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": 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{ "uniprot_canonical_ac": "D4A586-1", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related", "gene_name": "Hmg20b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSHGPRQPGAATAPAGGKTPGQHGAFVVAVKQERSEGPRAGEKGPQEEEPVKKRGWPKGKKRKKILPNGPKAPVTGYVRFLNERREQIRTRHPDLPFPEITKMLGAEWSKLQPAEKQRYLDEAEKEKQQYLKELWAYQQSEAYKVCTEKIQENKIKKEDSSSGLMNTLLNGHKGVDCGDGFSTFDVPIFTEEFLDQNKAREAELRRLRKMNVAFEEQNAVLQRHTQSMNSARERLEQELALEERRTLALQQQLQAVRQALTASFASLPVPGAQPRPQLWARPQPRARPQDVLLGPAPIPRQAPLPQYLSHLPDADLPVARTGETPTLGTLDFYMARLHGAIERDPAQHERLIARVKEILARVASEHL", "length": 367 }, "evidence": [ { "id": "RGD:1309235", "url": "https://alliancegenome.org/gene/RGD:1309235#orthology", "database": "AGR" }, { "id": "HGNC:5002", "url": "https://alliancegenome.org/gene/HGNC:5002#orthology", "database": "AGR" }, { "id": "MGI:1341190", "url": "https://alliancegenome.org/gene/MGI:1341190#orthology", "database": "AGR" }, { "id": "FB:FBgn0026582", "url": "https://alliancegenome.org/gene/FB:FBgn0026582#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9DC33-1", "protein_name": "High mobility group protein 20A", "gene_name": "Hmg20a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESLMASSTLPPLFADEDGSKESNDLATSGLTHPEGPYGSAATSTTNPEFVEDLSQGQLLQSEASNAVEGNEQRPEDEQRSKRGGWSKGRKRKKPLRDSNAPKSPLTGYVRFMNERREQLRAKRPEVPFPEITRMLGNEWSKLPPEEKQRYLDEADRDKERYMKELEQYQKTEAYKVFSRKTQDRQKGKSHRQDAARQATHDHEKETEVKERSVFDIPIFTEEFLNHSKAREAELRQLRKSNMEFEERNAALQKHVESMRTAVEKLEVDVIQERSRNTVLQQHLETLRQMLTSSFASMPLPGSGEIPTVDTIDSYMNRLHSIILANPQDNENFIATVREVVNRLDR", "length": 346 }, "evidence": [ { "id": "HGNC:5001", "url": "https://alliancegenome.org/gene/HGNC:5001#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-5107", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-5107#orthology", "database": "AGR" }, { "id": "MGI:1914117", "url": "https://alliancegenome.org/gene/MGI:1914117#orthology", "database": "AGR" }, { "id": "RGD:1564760", "url": "https://alliancegenome.org/gene/RGD:1564760#orthology", "database": "AGR" }, { "id": "FB:FBgn0026582", "url": "https://alliancegenome.org/gene/FB:FBgn0026582#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NP66-1", "protein_name": "High mobility group protein 20A", "gene_name": "HMG20A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MENLMTSSTLPPLFADEDGSKESNDLATTGLNHPEVPYSSGATSSTNNPEFVEDLSQGQLLQSESSNAAEGNEQRHEDEQRSKRGGWSKGRKRKKPLRDSNAPKSPLTGYVRFMNERREQLRAKRPEVPFPEITRMLGNEWSKLPPEEKQRYLDEADRDKERYMKELEQYQKTEAYKVFSRKTQDRQKGKSHRQDAARQATHDHEKETEVKERSVFDIPIFTEEFLNHSKAREAELRQLRKSNMEFEERNAALQKHVESMRTAVEKLEVDVIQERSRNTVLQQHLETLRQVLTSSFASMPLPGSGETPTVDTIDSYMNRLHSIILANPQDNENFIATVREVVNRLDR", "length": 347 }, "evidence": [ { "id": "HGNC:5001", "url": "https://alliancegenome.org/gene/HGNC:5001#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-5107", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-5107#orthology", "database": "AGR" }, { "id": "MGI:1914117", "url": "https://alliancegenome.org/gene/MGI:1914117#orthology", "database": "AGR" }, { "id": "RGD:1564760", "url": "https://alliancegenome.org/gene/RGD:1564760#orthology", "database": "AGR" }, { "id": "FB:FBgn0026582", "url": "https://alliancegenome.org/gene/FB:FBgn0026582#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9P0W2-1", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related", "gene_name": "HMG20B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"Q9W2L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W2L0" } ] } ], "protein_names": [ { "name": "EF-hand domain-containing protein", "type": "recommended", "evidence": [ { "id": "Q9W2L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W2L0/entry#names_and_taxonomy" } ] }, { "name": "CG9406-PA", "type": "synonym", "evidence": [ { "id": "NP_611552", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611552" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_611552", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611552" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W2L0", "url": "https://www.uniprot.org/uniprotkb/Q9W2L0" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "CBP5", "url": "https://www.uniprot.org/uniprotkb/Q9W2L0", "locus": { "chromosome": "2R", "start_pos": 21143261, "end_pos": 21142368, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0034592", "url": "https://www.ensemblgenomes.org/id/FBgn0034592" } ] } } ], "crossref": [ { "id": "FB:FBgn0034592", "url": "https://alliancegenome.org/gene/FB:FBgn0034592", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0034592", "url": "https://bgee.org/?page=gene&gene_id=FBgn0034592", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0034592", "url": "https://flybase.org/reports/FBgn0034592", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "37405", "url": "https://www.ncbi.nlm.nih.gov/gene/37405", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG9406", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG9406", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AFCVFDT", "url": "https://omabrowser.org/oma/group/AFCVFDT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W2L0", "url": "https://www.orthodb.org/?gene=Q9W2L0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46763", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46763", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46763:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46763:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "NP_611552", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611552", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W2L0", "url": "https://www.uniprot.org/uniprotkb/Q9W2L0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W2L0-1", "url": "https://www.uniprot.org/uniprotkb/Q9W2L0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEVGVTLNNELEEKISEAFCIFDTHGDKYIDSRNVGNVLRFLGCAPTEKEVEDVIKATDSVDYPGEAHLVKFMEHVSKLLMDRQMEPASSEKLLEAFETLDPENKKYLTKEYFGKLMAEEGEPFSAEELDAMWPVAIDPITGHIPYTFYINQLRHKPDIYEIAEVIKEELAQAEKEKGKKPQQPLF", "length": 186, "header": "tr|Q9W2L0-1|Q9W2L0_DROME Isoform 1 of EF-hand domain-containing protein OS=Drosophila melanogaster OX=7227 GN=CBP5 PE=4 SV=1 CANONICAL=Q9W2L0-1" }, "isoforms": [ { "isoform_ac": "Q9W2L0-1", "url": "https://www.uniprot.org/uniprotkb/Q9W2L0/entry#Q9W2L0-1", "sequence": { "sequence": "MEVGVTLNNELEEKISEAFCIFDTHGDKYIDSRNVGNVLRFLGCAPTEKEVEDVIKATDSVDYPGEAHLVKFMEHVSKLLMDRQMEPASSEKLLEAFETLDPENKKYLTKEYFGKLMAEEGEPFSAEELDAMWPVAIDPITGHIPYTFYINQLRHKPDIYEIAEVIKEELAQAEKEKGKKPQQPLF", "length": 186, "header": "tr|Q9W2L0-1|Q9W2L0_DROME Isoform 1 of EF-hand domain-containing protein OS=Drosophila melanogaster OX=7227 GN=CBP5 PE=4 SV=1 CANONICAL=Q9W2L0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W2L0", "url": "https://www.uniprot.org/uniprotkb/Q9W2L0" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W2L0", "url": "https://www.uniprot.org/uniprotkb/Q9W2L0" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2L0", "url": "https://www.uniprot.org/uniprotkb/Q9W2L0" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2L0", "url": "https://www.uniprot.org/uniprotkb/Q9W2L0" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W2L0", "url": "https://www.uniprot.org/uniprotkb/Q9W2L0" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W2L0", "url": "https://www.uniprot.org/uniprotkb/Q9W2L0" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W2L0", "url": "https://www.uniprot.org/uniprotkb/Q9W2L0" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2L0", "url": "https://www.uniprot.org/uniprotkb/Q9W2L0" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2L0", "url": "https://www.uniprot.org/uniprotkb/Q9W2L0" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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Clinical symptoms include pulmonary nodules and hemorrhage." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "0050073", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050073" } ] }, { "disease_id": "DOID:0050127", "recommended_name": { "id": "DOID:0050127", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050127", "name": "sinusitis", "description": "A paranasal sinus disease involving inflammation of the paranasal sinuses resulting from bacterial, fungal, viral infection, allergic or autoimmune issues. Symptoms can include fever, weakness, fatigue, cough and congestion. 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Symptoms may vary from mild to severe, and relapses and remissions may last for days or months. More than 80 percent of people who have MS begin with relapsing-remitting cycles." }, "synonyms": [ { "id": "DOID:2378", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2378", "name": "RRMS", "description": "" }, { "id": "DOID:2378", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2378", "name": "Relapsing-remitting MS", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "2378", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2378" } ] }, { "disease_id": "DOID:2841", "recommended_name": { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing." }, "synonyms": [ { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "bronchial hyperreactivity", "description": "" }, { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "chronic obstructive asthma", "description": "" }, { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "chronic obstructive asthma with acute exacerbation", "description": "" }, { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "chronic obstructive asthma with status asthmaticus", "description": "" }, { "id": "MONDO:0010940", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010940", "name": "inherited susceptibility to asthma", "description": "" }, { "id": "MONDO:0010940", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010940", "name": "asthma, nocturnal, susceptibility to", "description": "" }, { "id": "MIM:600807", "resource": "MIM", "url": "https://www.omim.org/entry/600807", "name": "Asthma", "description": "Asthma" } ], "unlinked_id_list": [ "DOID:0080811", "DOID:0080819" ], "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ] }, { "disease_id": "DOID:8869", "recommended_name": { "id": "DOID:8869", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8869", "name": "neuromyelitis optica", "description": "A central nervous system disease characterized by inflammation of the optic nerve (optic neuritis) and inflammation of the spinal cord (myelitis)." }, "synonyms": [ { "id": "DOID:8869", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8869", "name": "Devic's disease", "description": "" }, { "id": "DOID:8869", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8869", "name": "Devic's syndrome", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "8869", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8869" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W2M6", "url": "https://www.uniprot.org/uniprotkb/Q9W2M6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Cht4", "url": "https://www.uniprot.org/uniprotkb/Q9W2M6", "locus": { "chromosome": "2R", "start_pos": 21065379, "end_pos": 21067087, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0022700", "url": "https://www.ensemblgenomes.org/id/FBgn0022700" } ] } } ], "crossref": [ { "id": "FB:FBgn0022700", "url": "https://alliancegenome.org/gene/FB:FBgn0022700", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0022700", "url": "https://bgee.org/?page=gene&gene_id=FBgn0022700", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02872", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02872", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0022700", "url": "https://flybase.org/reports/FBgn0022700", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "49815", "url": "https://www.ncbi.nlm.nih.gov/gene/49815", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001223", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001223", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001579", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001579", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002557", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002557", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011583", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011583", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029070", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029070", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036508", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036508", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050314", "database": "InterPro", "categories": [ 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF01607", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-189085", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-189085", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_524962", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524962", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W2M6", "url": "https://www.uniprot.org/uniprotkb/Q9W2M6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W2M6-1", "url": "https://www.uniprot.org/uniprotkb/Q9W2M6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKLVSIWALAALCLCLGQVASSEKLLNCYWGTWANYRPGDGKFTPSDIDPSLCTHISYTFFGISDAGEFKSLDTWLDMDDGLGFISQTIALKQRNPNLKILAVVGGWNEGSTKYSAMAADPAKRATFVSTSLAFIQQYSFDGLDLDWEYPGQRGGSEADRENFVTLLREIKETYDQYGLELGIAVGASEKSASISYDIPAISQHLTFINVMTYDFHMALDGYLGLNAPLPEVAESIDYWLSHGAPAEKLILGIGFYGHSYQMSDSSQNWPGAACIGPGTAGVYTRENGFLGYHEICLNNWQTVFDQENGAPYAFQGDQWIGYDNPESIQLKMQLVESRNLGGAMMWSIETDDFRGLCGESYPLLKTMNRALGREVSGGSGGGGGGGGEGSVTPAPTAAPTSSPTPAPTPGGGSGGNECAQDGFFVLESDCNKFYQCVGGVRYDFQCGAGLCFNTITLNCDWP", "length": 462, "header": "tr|Q9W2M6-1|Q9W2M6_DROME Isoform 1 of chitinase OS=Drosophila melanogaster OX=7227 GN=Cht4 PE=3 SV=2 CANONICAL=Q9W2M6-1" }, "isoforms": [ { "isoform_ac": "Q9W2M6-1", "url": "https://www.uniprot.org/uniprotkb/Q9W2M6/entry#Q9W2M6-1", "sequence": { "sequence": "MKLVSIWALAALCLCLGQVASSEKLLNCYWGTWANYRPGDGKFTPSDIDPSLCTHISYTFFGISDAGEFKSLDTWLDMDDGLGFISQTIALKQRNPNLKILAVVGGWNEGSTKYSAMAADPAKRATFVSTSLAFIQQYSFDGLDLDWEYPGQRGGSEADRENFVTLLREIKETYDQYGLELGIAVGASEKSASISYDIPAISQHLTFINVMTYDFHMALDGYLGLNAPLPEVAESIDYWLSHGAPAEKLILGIGFYGHSYQMSDSSQNWPGAACIGPGTAGVYTRENGFLGYHEICLNNWQTVFDQENGAPYAFQGDQWIGYDNPESIQLKMQLVESRNLGGAMMWSIETDDFRGLCGESYPLLKTMNRALGREVSGGSGGGGGGGGEGSVTPAPTAAPTSSPTPAPTPGGGSGGNECAQDGFFVLESDCNKFYQCVGGVRYDFQCGAGLCFNTITLNCDWP", "length": 462, "header": "tr|Q9W2M6-1|Q9W2M6_DROME Isoform 1 of chitinase OS=Drosophila melanogaster OX=7227 GN=Cht4 PE=3 SV=2 CANONICAL=Q9W2M6-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 396, "start_aa": "Thr", "end_pos": 396, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr396", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 404, "start_aa": "Thr", "end_pos": 404, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr404", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 408, "start_aa": "Thr", "end_pos": 408, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr408", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W2M6", "url": "https://www.uniprot.org/uniprotkb/Q9W2M6" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W2M6", "url": "https://www.uniprot.org/uniprotkb/Q9W2M6" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2M6", "url": "https://www.uniprot.org/uniprotkb/Q9W2M6" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2M6", "url": "https://www.uniprot.org/uniprotkb/Q9W2M6" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W2M6", "url": "https://www.uniprot.org/uniprotkb/Q9W2M6" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W2M6", "url": "https://www.uniprot.org/uniprotkb/Q9W2M6" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W2M6", "url": "https://www.uniprot.org/uniprotkb/Q9W2M6" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2M6", "url": "https://www.uniprot.org/uniprotkb/Q9W2M6" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2M6", "url": "https://www.uniprot.org/uniprotkb/Q9W2M6" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W2M6", "url": "https://www.uniprot.org/uniprotkb/Q9W2M6" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W2M6", "url": "https://www.uniprot.org/uniprotkb/Q9W2M6" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG3986", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3986", "resource": "KEGG Pathway" }, { "id": "R-DME-189085", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-189085", "resource": "Reactome", "description": "Digestion of dietary carbohydrate" }, { "id": "R-DME-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JDS2-1", "protein_name": "Chitinase-like 5", "gene_name": "Chil5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTKLILVTGLALLLNPQLGSAYQLMCYYNNVAQNRPKLGSFNPADIDPCLCTHLIYAFAGMQNNKVTMRSMNDLTDYQALNTLKSRNVQLKTLLAIGGRDFGPAPFSAMVSTPHNQQTFINSAIKFLRQYGFDGLNLDWQFPGSRGSPSRDKHLFTVLVQKIREAFELEAIENKSPRLMVTATVAGVISTIQSGYEIPQLSHFLDYIQVMTYNLHGSQDGYTGENSPLYKSLNDTGINTLLNVDYIMTYWNENGAAPEKLIVGFPAYGQTFTLSDPSNNGISAPTASAGTLGPYTEESGTWAYYEICSFLNDGATEAWDSAQEVPYAYQGNKWVGYDNVKSFRIKAEWLKQNNLGGAMLWTLDMDDFTGSFCNQGQFPLTSTLKNALLVYSTSCMASVSDLQQVNAPLYSGNRNWKRGSKAMDSVSPVPRE", "length": 431 }, "evidence": [ { "id": "MGI:2676649", "url": "https://alliancegenome.org/gene/MGI:2676649#orthology", "database": "AGR" }, { "id": "HGNC:17432", "url": "https://alliancegenome.org/gene/HGNC:17432#orthology", "database": "AGR" }, { "id": "FB:FBgn0022700", "url": "https://alliancegenome.org/gene/FB:FBgn0022700#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0AC58GSW9-1", "protein_name": "Chitinase-3-like protein 1 isoform X1", "gene_name": "ovgp1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MIWTCSSNKMNRGITHLIGLNLLFQFVACSKLVCYFTNWSQYRSGTARYLPENVDPNLCTHLIYAFAIINYANNIAGSEWNDVVHYSTFNALKKRNPQLITLLSVRDQDSSQFSIMLSKWINRQTFIKSSIEFLRKYNFDGLDLDWEMKNTSEMHPEDKLKFTLLCKELLEAFVAESLNSDTRLILTATVSAQKDVIERSYIIPEISEYLDFINVKTFDFHTYKDGIARHHSALYSAMSDDKDIKSNTDFALQYWRSQGAPAEKLLMGFSTYGRSFILNSSQNGVGAPANKFASPGPHTQEIGLWAYYEICLFLNGGVVQWIEDQKVPFSVKGNDWVGFDSLRSFNIKTKYLLEHGFGGAFVWALDLDDFSGYFCGQGTYPLVNSLKKSLIHGIESSSSMTSTNFFFSIFATAGKGSLPTPICVKIVRSFSAQQSLFCANRSDGLYYRTNSLNSFYSCSEGITNITWCTPFHAISNNSRKVQLSLMIIFITLGSAGFLTKMLI", "length": 503 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-140106-118", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140106-118#orthology", "database": "AGR" }, { "id": "FB:FBgn0022700", "url": "https://alliancegenome.org/gene/FB:FBgn0022700#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D4A2D4-1", "protein_name": "Chitinase acidic-like 1", "gene_name": "Chial1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLYKTSEDPAGSVLRAFISKLVFIMGLNLLLNVQLDSAYQLMCYFNNWPQYQPDVRGMKLDDIDPCLCTHLIYSFAGIWENNNTMTKRKDLDDYKEFNDLKKRNNKLKTLLSIGCWNFEAGLFITMVSTPESRHTFITSVRKFLRKYGFDGLNLAWQYPGCYGSPPKDKHLFTILTQEIRKAFEKEVSKNKKSRLIITAALAGVISPIQFGYHVPQLSQSLDYIQVMTYDLHGSWDGYTGENSPLYKSPAETGVKAFYNIKYTMHNWKNKGVSPEKLIVGFPAYGHTFILSDSTKTEIGAPSNRGGHPGPYTKKTGFWAYYEICAFLKNGAIQVWNAAQQVPYAFHGNEWVGYDNVKSFHIKAQWLKNNNFGGAMIWAIGMDDYTGSFCDQGPFPLTSTLKNALKVHSASCKVTALSANVTGSRDSNFGALEPLFQLSSK", "length": 440 }, "evidence": [ { "id": "HGNC:17432", "url": "https://alliancegenome.org/gene/HGNC:17432#orthology", "database": "AGR" }, { "id": "FB:FBgn0022700", "url": "https://alliancegenome.org/gene/FB:FBgn0022700#orthology", "database": "AGR" }, { "id": "RGD:1309110", "url": "https://alliancegenome.org/gene/RGD:1309110#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M559-1", "protein_name": "Chitinase 3-like 3", "gene_name": "Chi3l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKLILATGLAILLYAHLGSSYQLMCYYTSWAKDRPTVGSFKIGNIDPCLCTHLIYAFAGMRNNEIINTSEQDLIDYEAINYLKDRNTELKTLLAIGGWKFGSAPFSAMVSTPQNRQTFIKSVIKFLRQYKFDGLNLDWQYPGSRGSPPKDKHLFSVLVQEMRKAFEKESTEQEIPRLLLTATVAGVIDTIQSGYKIPELSQSLDYFQVMTYNLHDFQNGYTRENSPLYQSPSDTGIYAYLNVDAIISYWKDNGAAREKLIVGFPAYGHNFILSDPSNTGINAPIVSTGPPGKFTGEAGLWAYYEICTFLNDGATDLWDGPQEVPYAVQGNVWVGYDNVKSFKIKAQWLKDNKLGGAMVWPLDMDDFTGSFCQQGRFPLTSTLKHYLGVQSTNCMAYKEEL", "length": 401 }, "evidence": [ { "id": "MGI:1330860", "url": "https://alliancegenome.org/gene/MGI:1330860#orthology", "database": "AGR" }, { "id": "MGI:1341098", "url": "https://alliancegenome.org/gene/MGI:1341098#orthology", "database": "AGR" }, { "id": "HGNC:17432", "url": "https://alliancegenome.org/gene/HGNC:17432#orthology", "database": "AGR" }, { "id": "FB:FBgn0022700", "url": "https://alliancegenome.org/gene/FB:FBgn0022700#orthology", "database": "AGR" }, { "id": "RGD:1308790", "url": "https://alliancegenome.org/gene/RGD:1308790#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O35744-1", "protein_name": "Chitinase-like protein 3", "gene_name": "Chil3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKLILVTGLAILLNVQLGSSYQLMCYYTSWAKDRPIEGSFKPGNIDPCLCTHLIYAFAGMQNNEITYTHEQDLRDYEALNGLKDKNTELKTLLAIGGWKFGPAPFSAMVSTPQNRQIFIQSVIRFLRQYNFDGLNLDWQYPGSRGSPPKDKHLFSVLVKEMRKAFEEESVEKDIPRLLLTSTGAGIIDVIKSGYKIPELSQSLDYIQVMTYDLHDPKDGYTGENSPLYKSPYDIGKSADLNVDSIISYWKDHGAASEKLIVGFPAYGHTFILSDPSKTGIGAPTISTGPPGKYTDESGLLAYYEVCTFLNEGATEVWDAPQEVPYAYQGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSGSFCHQRHFPLTSTLKGDLNIHSASCKGPY", "length": 398 }, "evidence": [ { "id": "MGI:1330860", "url": "https://alliancegenome.org/gene/MGI:1330860#orthology", "database": "AGR" }, { "id": "HGNC:17432", "url": "https://alliancegenome.org/gene/HGNC:17432#orthology", "database": "AGR" }, { "id": "FB:FBgn0022700", "url": "https://alliancegenome.org/gene/FB:FBgn0022700#orthology", "database": "AGR" }, { "id": "RGD:1308790", "url": "https://alliancegenome.org/gene/RGD:1308790#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O81862-1", "protein_name": "Class V chitinase", "gene_name": "ChiC", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSTKLISLIVSITFFLTLQCSMAQTVVKASYWFPASEFPVTDIDSSLFTHLFCAFADLNSQTNQVTVSSANQPKFSTFTQTVQRRNPSVKTLLSIGGGIADKTAYASMASNPTSRKSFIDSSIRVARSYGFHGLDLDWEYPSSATEMTNFGTLLREWRSAVVAEASSSGKPRLLLAAAVFYSNNYYSVLYPVSAVASSLDWVNLMAYDFYGPGWSRVTGPPAALFDPSNAGPSGDAGTRSWIQAGLPAKKAVLGFPYYGYAWRLTNANSHSYYAPTTGAAISPDGSIGYGQIRKFIVDNGATTVYNSTVVGDYCYAGTNWIGYDDNQSIVTKVRYAKQRGLLGYFSWHVGADDNSGLSRAASQAWDATTATTRTIQKV", "length": 379 }, "evidence": [ { "id": "Q9W2M6", "url": "https://omabrowser.org/oma/group/Q9W2M6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P36222-1", "protein_name": "Chitinase-3-like protein 1", "gene_name": "CHI3L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGVKASQTGFVVLVLLQCCSAYKLVCYYTSWSQYREGDGSCFPDALDRFLCTHIIYSFANISNDHIDTWEWNDVTLYGMLNTLKNRNPNLKTLLSVGGWNFGSQRFSKIASNTQSRRTFIKSVPPFLRTHGFDGLDLAWLYPGRRDKQHFTTLIKEMKAEFIKEAQPGKKQLLLSAALSAGKVTIDSSYDIAKISQHLDFISIMTYDFHGAWRGTTGHHSPLFRGQEDASPDRFSNTDYAVGYMLRLGAPASKLVMGIPTFGRSFTLASSETGVGAPISGPGIPGRFTKEAGTLAYYEICDFLRGATVHRILGQQVPYATKGNQWVGYDDQESVKSKVQYLKDRQLAGAMVWALDLDDFQGSFCGQDLRFPLTNAIKDALAAT", "length": 383 }, "evidence": [ { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q06350-1", "protein_name": "Sporulation-specific chitinase 2", "gene_name": "CTS2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVGHSAQHRSKSSLVSHLLILLIFITIIIEMCLYNKIFKNQRSDDIRDNFNNGGHRVPSNVQNHGTHIRDEAFISGVYYSNWSPYKPRFHFPHDINLKQVSHIYYAFFKINSRTGGIENTDSWSDLEMNLYKSLAIKNSELIKESSNNSVQNILPLGCIGELFYLKNTCSDKKFKVIMSIGGWSDSENFKIIIKDDKLLQNFVDSSVETMFRLGFDGIDLDWEFPGNNESEPRGYLKLVRMLRLKLNSLESQIFGKRTEDHFQLSIAAPAFKDKLFYLPITEIDQYVDYWNMMTYDYYGSWSETTGYHSNLFSETELNGNFAMHYMIDRFGVNSRKLVLGMAAYGRSFHIKDNKFEPFNQNTVLINKIFKGVGKPTKEIDKADGKEGIWPYKNLPKIGTIEQYDPKYVSAYCFDEKNSIFISYDNTKSVKTKAEYVTHNNLGGGFWWESCGEAYANESRSLINAFNEGLHFNVSSKPSIFQDVRVKKYYLNKYGDGGFLSPYLKHLDSRKQ", "length": 511 }, "evidence": [ { "id": "RGD:1303058", "url": "https://alliancegenome.org/gene/RGD:1303058#orthology", "database": "AGR" }, { "id": "MGI:1919134", "url": "https://alliancegenome.org/gene/MGI:1919134#orthology", "database": "AGR" }, { "id": "MGI:2676649", "url": "https://alliancegenome.org/gene/MGI:2676649#orthology", "database": "AGR" }, { "id": "MGI:1330860", "url": "https://alliancegenome.org/gene/MGI:1330860#orthology", "database": "AGR" }, { "id": "MGI:1341098", "url": "https://alliancegenome.org/gene/MGI:1341098#orthology", "database": "AGR" }, { "id": "MGI:1932052", "url": "https://alliancegenome.org/gene/MGI:1932052#orthology", "database": "AGR" }, { "id": "HGNC:17432", "url": "https://alliancegenome.org/gene/HGNC:17432#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-140106-118", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140106-118#orthology", "database": "AGR" }, { "id": "FB:FBgn0022700", "url": "https://alliancegenome.org/gene/FB:FBgn0022700#orthology", "database": "AGR" }, { "id": "RGD:1308790", "url": "https://alliancegenome.org/gene/RGD:1308790#orthology", "database": "AGR" }, { "id": "RGD:1309110", "url": "https://alliancegenome.org/gene/RGD:1309110#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q12889-1", "protein_name": "Oviduct-specific glycoprotein", "gene_name": "OVGP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWKLLLWVGLVLVLKHHDGAAHKLVCYFTNWAHSRPGPASILPHDLDPFLCTHLIFAFASMNNNQIVAKDLQDEKILYPEFNKLKERNRELKTLLSIGGWNFGTSRFTTMLSTFANREKFIASVISLLRTHDFDGLDLFFLYPGLRGSPMHDRWTFLFLIEELLFAFRKEALLTMRPRLLLSAAVSGVPHIVQTSYDVRFLGRLLDFINVLSYDLHGSWERFTGHNSPLFSLPEDPKSSAYAMNYWRKLGAPSEKLIMGIPTYGRTFRLLKASKNGLQARAIGPASPGKYTKQEGFLAYFEICSFVWGAKKHWIDYQYVPYANKGKEWVGYDNAISFSYKAWFIRREHFGGAMVWTLDMDDVRGTFCGTGPFPLVYVLNDILVRAEFSSTSLPQFWLSSAVNSSSTDPERLAVTTAWTTDSKILPPGGEAGVTEIHGKCENMTITPRGTTVTPTKETVSLGKHTVALGEKTEITGAMTMTSVGHQSMTPGEKALTPVGHQSVTTGQKTLTSVGYQSVTPGEKTLTPVGHQSVTPVSHQSVSPGGTTMTPVHFQTETLRQNTVAPRRKAVAREKVTVPSRNISVTPEGQTMPLRGENLTSEVGTHPRMGNLGLQMEAENRMMLSSSPVIQLPEQTPLAFDNRFVPIYGNHSSVNSVTPQTSPLSLKKEIPENSAVDEEA", "length": 678 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-140106-118", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140106-118#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q13231-1", "protein_name": "Chitotriosidase-1", "gene_name": "CHIT1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVRSVAWAGFMVLLMIPWGSAAKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWNDETLYQEFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYPGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLILGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSWKGATKQRIQDQKVPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQGRYPLIQTLRQELSLPYLPSGTPELEVPKPGQPSEPEHGPSPGQDTFCQGKADGLYPNPRERSSFYSCAAGRLFQQSCPTGLVFSNSCKCCTWN", "length": 466 }, "evidence": [ { "id": "MGI:1919134", "url": "https://alliancegenome.org/gene/MGI:1919134#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q15782-4", "protein_name": "Chitinase-3-like protein 2", "gene_name": "CHI3L2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGATTMDQKSLWAGVVVLLLLQGGSAYKLVCYFTNWSQDRQEPGKFTPENIDPFLCSHLIYSFASIENNKVIIKDKSEVMLYQTINSLKTKNPKLKILLSIGGYLFGSKGFHPMVDSSTSRLEFINSIILFLRNHNFDGLDVSWIYPDQKENTHFTVLIHELAEAFQKDFTKSTKERLLLTAGVSAGRQMIDNSYQVEKLAKDLDFINLLSFDFHGSWEKPLITGHNSPLSKGWQDRGPSSYYNVEYAVGYWIHKGMPSEKVVMGIPTYGHSFTLASAETTVGAPASGPGAAGPITESSGFLAYYEICQFLKGAKITRLQDQQVPYAVKGNQWVGYDDVKSMETKVQFLKNLNLGGAMIWSIDMDDFTGKSCNQGPYPLVQAVKRSLGSL", "length": 390 }, "evidence": [ { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q23997-1", "protein_name": "Imaginal disk growth factor 6", "gene_name": "Idgf6", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MIIKALAIVSLCLASIQASKVGAPQLPKKHLVCYYDSASFVKEGLGKLVIDELEPALQFCDYLVYGYAGIERDSHKAVSLNQQLDLDLGKGLYRTVTRLKRKYPNVKILLSVGGDKDIELDKDAKELPNKYLELLESPTGRTRFVNTVYSLVKTYGFDGLDVAWQFPKNKPKKVHSGIGSLWKGFKKVFSGDSIVDEKSEEHKEQFTALLRDVKNAFRPDNLLLSTTVLPNVNSSLFYDIPAVVNYLDFVNLGTFDFFTPQRNPEVADYAAPIYELSERNPEFNVAAQVKYWLRNNCPASKINVGVATYGRPWKLTDDSGDTGVPPVKDVKDEAPVGGNTQVPGIYSWPEVCALLPNQNNAYLKGANAPLIKVQDPAKRFGSYAYRAADKKGDNGIWVSFEDPDTAADKAGYVRTENLGGVALFDLSYDDFRGLCTNEKYPILRAIKYRLTN", "length": 452 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-140106-118", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140106-118#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q61362-1", "protein_name": "Chitinase-3-like protein 1", "gene_name": "Chi3l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHTSTEARMGMRAALTGFAVLMLLQSCSAYKLVCYFTSWSQYREGVGSFLPDAIQPFLCTHIIYSFANISSDNMLSTWEWNDESNYDKLNKLKTRNTNLKTLLSVGGWKFGEKRFSEIASNTERRTAFVRSVAPFLRSYGFDGLDLAWLYPRLRDKQYFSTLIKELNAEFTKEVQPGREKLLLSAALSAGKVAIDTGYDIAQIAQHLDFINLMTYDFHGVWRQITGHHSPLFQGQKDTRFDRYSNVNYAVQYMIRLGAQASKLLMGIPTFGKSFTLASSENQLGAPISGEGLPGRFTKEAGTLAYYEICDFLKGAEVHRLSNEKVPFATKGNQWVGYEDKESVKNKVGFLKEKKLAGAMVWALDLDDFQGTCQPKEFFPLTNAIKDALA", "length": 389 }, "evidence": [ { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q62010-1", "protein_name": "Oviduct-specific glycoprotein", "gene_name": "Ovgp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGRLLLLAGLVLLMKHSDGTAYKLVCYFTNWAHSRPGPASIMPHDLDPFLCTHLIFAFASMSNNQIVAKNLQDENVLYPEFNKLKERNRELKTLLSIGGWNFGTSRFTAMLSTLANREKFIDSVISFLRIHGFDGLDLFFLYPGLRGSPPHDRWNFLFLIEELQFAFEREALLTQHPRLLLSAAVSGIPSIIHTSYDALLLGRRLDFINVLSYDLHGSWEKFTGHNSPLFSLPEDSKSSAYAMNYWRKLGTPADKLIMGFPTYGRNFYLLKESKNGLQTASMGPASPGKYTKQAGFLAYYEVCSFVQRAKKHWIDYQYVPYAFKGKEWLGYDDTISFSYKAMYVKREHFGGAMVWTLDMDDVRGTFCGNGPFPLVHILNELLVQTESNSTPLPQFWFTSSVNASGPGSENTALTEVLTTDTIKILPPGGEAMTTEVHRRYENMTTVPSDGSVTPGGTASPRKHAVTPENNTMAAEAKTMSTLDFFSKTTTGVSKTTTGISKTTTGVSKTTTGVSKATAGISKTIPEISKATAGVSKTTTGVSKTTTGISKTITGVSKTTTGISKTTTGISKTTTGVSKITTGVSKTTTGISKTTTGISQTTTGISKTTTDISKTTTGISKTTPGISKTTPGMTVIVQTQANEAETTATMDHQSVTPTEMDTTLFYLKTMTPSEKETSRKKTMVLEKATVSPREMSATPNGQSKTLKWASLITEVETYSQDG", "length": 721 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-140106-118", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140106-118#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6RY07-1", "protein_name": "Acidic mammalian chitinase", "gene_name": "Chia", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKLILVTGLVLLLNVQLGSAYNLVCYFTNWAQYRPGLGSFKPDDINPCLCTHLIYAFAGMQNNQITTIEWNDVTLYKAFNDLKNRNSKLKTLLAIGGWNFGTAPFTTMVSTSQNRQTFITSVIKFLRQYGFDGLDLDWEYPGSRGSPPQDKHLFTVLVKELREAFEQEAIESNRPRLMVTAAVAAGISNIQAGYEIPELSQYLDFIHVMTYDLHGSWDGYTGENSPLYKLPTETGSNAYLNVDYVMNYWKDNGAPAEKLIVGFPEYGHTYILSNPSDTGIGAPTSGNGPAGPYTRQAGFWAYYEICTFLRNGATQDWDAPQEVPYAYKGNEWVGYDNIKSFSVKAQWLKQNNFGGAMIWAIDLDDFTGSFCDQGKFPLTSTLNKALDIPTAGCTAPDLPSEPVTTPPGSGSGGGSSGGGSEGSGFCAGKADGLYPVADDRNAFWHCINGITYQQHCQAGLVFDTSCNCCNWP", "length": 473 }, "evidence": [ { "id": "RGD:1303058", "url": "https://alliancegenome.org/gene/RGD:1303058#orthology", "database": "AGR" }, { "id": "MGI:1932052", "url": "https://alliancegenome.org/gene/MGI:1932052#orthology", "database": "AGR" }, { "id": "HGNC:17432", "url": "https://alliancegenome.org/gene/HGNC:17432#orthology", "database": "AGR" }, { "id": "FB:FBgn0022700", "url": "https://alliancegenome.org/gene/FB:FBgn0022700#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8MLW8-1", "protein_name": "3.2.1.14", "gene_name": "Cht12", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTSFQYVFMIMIFLICGCIAKEYNVFCQYDLGSYYYKGRSQFFEWHLDSRLCTHLVLGSGIGVDGDSGELRITDKILLLEKDKLSSVKTMKWDSIKKVMFTIGGWEEDSSSFSRMVASPKKRDNFYSSMLEFMFRWGFDGVQIDWRYPTLLGGHPDDRQNFVILLEELGLIFRKNQLILMVAVLGRRDNRILESYNIPEIVNHSDFIHLMMHDEQDPYHLRLAYNAPLVGYEGSVTDSIMHWKRNGGAPEKLILGIPLFVRSFTMDRNQSTVGSACKGPGRQTKQSHRPGFMTYNEWCVQQSKWSRMFDQLAKVPYATRGDQWVSYENPRSIWAKMHLLQEHKLGGAMAWTIDVDDFRGRCGEQHGLLRVIFSALGDKNGLTTEKPTTEASGLCPHDGFSRDGWDCRLYHECRDGERIYYECLEGQYFDENQIVCRPAAEVKCDQNFVIWRPGMPVYSYDNMPLNLKIVE", "length": 470 }, "evidence": [ { "id": "MGI:2676649", "url": "https://alliancegenome.org/gene/MGI:2676649#orthology", "database": "AGR" }, { "id": "MGI:1330860", "url": "https://alliancegenome.org/gene/MGI:1330860#orthology", "database": "AGR" }, { "id": "MGI:1341098", "url": "https://alliancegenome.org/gene/MGI:1341098#orthology", "database": "AGR" }, { "id": "MGI:1932052", "url": "https://alliancegenome.org/gene/MGI:1932052#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8MLZ7-1", "protein_name": "Chitinase-like protein Idgf3", "gene_name": "Idgf3", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTGSLWLSLALSLAVLAQFKVSAAPNLVCFYDSQGSQRQGLAQFSMIDIELALQFCTHLVYGYAGVNADNYEMQSINKRLDLEQRHLAQITSMKERYPHIKFLLSVGGDADTYEGNQYIKLLESGQQGHRRFIESARDLVRRYNFDGLDLALQLPRNKPRKVHGDVGSAWKSFKKFFTGDFIVDTESETHKGQVTALIKDLSAALKQNDLLLSLTVLPNVNSSWYYDAPSIAPSLDFINLGTFDFLTPQRNPEEADFSAPTYEAVGQNRLGHYNLNFQMEHWLLQRVPANKINIGIATYGRSWKMSKDSGDSGMPVVPSTQGPAPAGPQSKQEGLLNWAEICSLMPNPSNSNARGPNAPVKRVVDPTKRYGSYAFRAADENGDHGLWISYDDPDSASSKAMYARARNLGGVALFDLTQDDFRGQCTNDRFPMLRAIKYRLL", "length": 441 }, "evidence": [ { "id": "MGI:1919134", "url": "https://alliancegenome.org/gene/MGI:1919134#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-140106-118", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140106-118#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8MM24-1", "protein_name": "Chitinase-like protein Idgf1", "gene_name": "Idgf1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRFQLFYILGLLSVTSLTHAASNLICYYDSNSYLRQGLAKMHTNELDLALQFCTHLVYGYAGLKSGTLELFSLNVDLDMFYYKDITALRQKFPQLKILLSVGGDRDVDEAHPNKYVELLEANRTAQQNFIDSSMILLKRNGFDGLDLAFQLPRNKPRKVHGSLGSYWKSFKKLFTGDFVVDPQAEEHKSQFTDLVGNIKNAFRSANLMLSLTVLPNVNSTWYFDVPKLHPQFDYINLAAFDFLTPLRNPEEADFTAPIFFQDEQNRLPHLNVEFQINYWLQNHCPGQKLNLGIASYGRAWKLSKGSGLSGAPIVHETCGVAPGGIQIQSAEGLLSWPEICSKLSQNASAQYRGELAPLRKVTDLTQKYGNYALRPADDNGDFGVWLSFDDPDFAGIKAVYAKGKGLGGIALFDLSYDDFRGLCTGQKYPILRSIKYFMG", "length": 439 }, "evidence": [ { "id": "MGI:1919134", "url": "https://alliancegenome.org/gene/MGI:1919134#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-140106-118", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140106-118#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8T0R7-1", "protein_name": "Chitinase-like protein Idgf5", "gene_name": "Idgf5", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MMWIQKNPFLGLLLCSFLAFFQSTYAEVGKLVCFYDAQSFVREGPAQMSLAELEPALQFCNFLVYGYAGIDAVTYKIKSLDPSLTNDRQHYRHITALRKKYPHVRFLLSVGGDRDVNSEGVADSDKYLRLLEQSEHRKSFQASVLAELNNNGFDGIDLAWQFPKNRPKLQQGVFKRVWGSLRGWFSSSSVDEKSEEHREQFATLLEELQSDLRRGGQLLTVSMLPHVSAELFIDVPKVLSNVDFVNLGTYDFQTPERDPKVADLPTPLYAMYDRDPSHNVQYQVQYWMNQTSEISVHKLHVGVTSYGRAWNMTRNSGITGYPPIPAANGAAPPGRQTVTPGLLSWPEICDLLQQQPQDREVPHLRKVGDPTKRFGIYAYRAADDQGENGLWVGYEDPLTAAIKAGFVHAQGLGGVAFHDLSMDDFRGQCAGEKFPILRSIKFKL", "length": 444 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-140106-118", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140106-118#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q91XA9-1", "protein_name": "Acidic mammalian chitinase", "gene_name": "Chia", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKLLLVTGLALLLNAQLGSAYNLICYFTNWAQYRPGLGSFKPDDINPCLCTHLIYAFAGMQNNEITTIEWNDVTLYKAFNDLKNRNSKLKTLLAIGGWNFGTAPFTTMVSTSQNRQTFITSVIKFLRQYGFDGLDLDWEYPGSRGSPPQDKHLFTVLVKEMREAFEQEAIESNRPRLMVTAAVAGGISNIQAGYEIPELSKYLDFIHVMTYDLHGSWEGYTGENSPLYKYPTETGSNAYLNVDYVMNYWKNNGAPAEKLIVGFPEYGHTFILRNPSDNGIGAPTSGDGPAGPYTRQAGFWAYYEICTFLRSGATEVWDASQEVPYAYKANEWLGYDNIKSFSVKAQWLKQNNFGGAMIWAIDLDDFTGSFCDQGKFPLTSTLNKALGISTEGCTAPDVPSEPVTTPPGSGSGGGSSGGSSGGSGFCADKADGLYPVADDRNAFWQCINGITYQQHCQAGLVFDTSCNCCNWP", "length": 473 }, "evidence": [ { "id": "RGD:1303058", "url": "https://alliancegenome.org/gene/RGD:1303058#orthology", "database": "AGR" }, { "id": "MGI:1932052", "url": "https://alliancegenome.org/gene/MGI:1932052#orthology", "database": "AGR" }, { "id": "HGNC:17432", "url": "https://alliancegenome.org/gene/HGNC:17432#orthology", "database": "AGR" }, { "id": "FB:FBgn0022700", "url": "https://alliancegenome.org/gene/FB:FBgn0022700#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q91Z98-1", "protein_name": "Chitinase-like protein 4", "gene_name": "Chil4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKLILVTGLAILLNVQLGSSYQLMCYYTSWAKDRPTEGSFKPGNIDPCLCTHLIYAFAGMKNNEITYLSEQDLRDYEALNGLKDRNTELKTLLAIGGWKFGPAPFSSMVSTPQNRQTFIKSVIRFLRQYNFDGLNLDWQYPGSRGSPPKDKHLFSVLVQEMRKAFEEESTLNHIPRLLLTSTGAGFIDVIKSGYKIPELSQSLDYIQVMTYDLHDPKNGYTGENSPLYKSPYDIGKSADLNVDSIITYWKDHGAASEKLIVGFPAYGHTFILSDPSKNGIGDPTVSAGPPGKYTNEQGLLAYFEICTFLNEGATEIFDATQEVPYAYLGNEWVGYDNVRSFKLKAQWLKDNNLGGAVVWPLDMDDFSGSFCHQGRFPLTTTLKRDLNVHSASCKASYRGEL", "length": 402 }, "evidence": [ { "id": "MGI:1341098", "url": "https://alliancegenome.org/gene/MGI:1341098#orthology", "database": "AGR" }, { "id": "HGNC:17432", "url": "https://alliancegenome.org/gene/HGNC:17432#orthology", "database": "AGR" }, { "id": "FB:FBgn0022700", "url": "https://alliancegenome.org/gene/FB:FBgn0022700#orthology", "database": "AGR" }, { "id": "RGD:1308790", "url": "https://alliancegenome.org/gene/RGD:1308790#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BZP6-1", "protein_name": "Acidic mammalian chitinase", "gene_name": "CHIA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTKLILLTGLVLILNLQLGSAYQLTCYFTNWAQYRPGLGRFMPDNIDPCLCTHLIYAFAGRQNNEITTIEWNDVTLYQAFNGLKNKNSQLKTLLAIGGWNFGTAPFTAMVSTPENRQTFITSVIKFLRQYEFDGLDFDWEYPGSRGSPPQDKHLFTVLVQEMREAFEQEAKQINKPRLMVTAAVAAGISNIQSGYEIPQLSQYLDYIHVMTYDLHGSWEGYTGENSPLYKYPTDTGSNAYLNVDYVMNYWKDNGAPAEKLIVGFPTYGHNFILSNPSNTGIGAPTSGAGPAGPYAKESGIWAYYEICTFLKNGATQGWDAPQEVPYAYQGNVWVGYDNIKSFDIKAQWLKHNKFGGAMVWAIDLDDFTGTFCNQGKFPLISTLKKALGLQSASCTAPAQPIEPITAAPSGSGNGSGSSSSGGSSGGSGFCAVRANGLYPVANNRNAFWHCVNGVTYQQNCQAGLVFDTSCDCCNWA", "length": 476 }, "evidence": [ { "id": "RGD:1303058", "url": "https://alliancegenome.org/gene/RGD:1303058#orthology", "database": "AGR" }, { "id": "MGI:2676649", "url": "https://alliancegenome.org/gene/MGI:2676649#orthology", "database": "AGR" }, { "id": "MGI:1330860", "url": "https://alliancegenome.org/gene/MGI:1330860#orthology", "database": "AGR" }, { "id": "MGI:1341098", "url": "https://alliancegenome.org/gene/MGI:1341098#orthology", "database": "AGR" }, { "id": "MGI:1932052", "url": "https://alliancegenome.org/gene/MGI:1932052#orthology", "database": "AGR" }, { "id": "HGNC:17432", "url": "https://alliancegenome.org/gene/HGNC:17432#orthology", "database": "AGR" }, { "id": "FB:FBgn0022700", "url": "https://alliancegenome.org/gene/FB:FBgn0022700#orthology", "database": "AGR" }, { "id": "RGD:1308790", "url": "https://alliancegenome.org/gene/RGD:1308790#orthology", "database": "AGR" }, { "id": "RGD:1309110", "url": "https://alliancegenome.org/gene/RGD:1309110#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D7Q1-1", "protein_name": "Chitotriosidase-1", "gene_name": "Chit1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVQSLAWAGVMTLLMVQWGSAAKLVCYLTNWSQYRTEAVRFFPRDVDPNLCTHVIFAFAGMDNHQLSTVEHNDELLYQELNSLKTKNPKLKTLLAVGGWTFGTQKFTDMVATASNRQTFVKSALSFLRTQGFDGLDLDWEFPGGRGSPTVDKERFTALIQDLAKAFQEEAQSSGKERLLLTAAVPSDRGLVDAGYEVDKIAQSLDFINLMAYDFHSSLEKTTGHNSPLYKRQGESGAAAEQNVDAAVTLWLQKGTPASKLILGMPTYGRSFTLASSSDNGVGAPATGPGAPGPYTKDKGVLAYYEACSWKERHRIEDQKVPYAFQDNQWVSFDDVESFKAKAAYLKQKGLGGAMVWVLDLDDFKGSFCNQGPYPLIRTLRQELNLPSETPRSPEQIIPEPRPSSMPEQGPSPGLDNFCQGKADGVYPNPGDESTYYNCGGGRLFQQSCPPGLVFRASCKCCTWS", "length": 464 }, "evidence": [ { "id": "MGI:1919134", "url": "https://alliancegenome.org/gene/MGI:1919134#orthology", "database": "AGR" }, { "id": "FB:FBgn0022700", "url": "https://alliancegenome.org/gene/FB:FBgn0022700#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9V3D4-1", "protein_name": "Chitinase-like protein Idgf2", "gene_name": "Idgf2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKAWIWFTFVACLFAASTEAASNLVCYYDSSSYTREGLGKLLNPDLEIALQFCSHLVYGYAGLRGENLQAYSMNENLDIYKHQFSEVTSLKRKYPHLKVLLSVGGDHDIDPDHPNKYIDLLEGEKVRQIGFIRSAYDLVKTYGFDGLDLAYQFPKNKPRKVHGDLGLAWKSIKKLFTGDFIVDPHAALHKEQFTALVRDVKDSLRADGFLLSLTVLPNVNSTWYFDIPALNGLVDFVNLATFDFLTPARNPEEADYSAPIYHPDGSKDRLAHLNADFQVEYWLSQGFPSNKINLGVATYGNAWKLTKDSGLEGVPVVPETSGPAPEGFQSQKPGLLSYAEICGKLSNPQNQFLKGNESPLRRVSDPTKRFGGIAYRPVDGQITEGIWVSYDDPDSASNKAAYARVKNLGGVALFDLSYDDFRGQCSGDKYPILRAIKYRL", "length": 440 }, "evidence": [ { "id": "MGI:1919134", "url": "https://alliancegenome.org/gene/MGI:1919134#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-140106-118", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140106-118#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VFR3-1", "protein_name": "chitinase", "gene_name": "Cht5", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVRYIPLLLLGVLCSWPAATVASDQASRIVCYFSNWAVYRTGIGRYGLEDVPADLCTHIIYSFIGVNDKSWDVLVIDPELDVDQGGFSKFTQLKKSNPNVKLEIAVGGWAEGGSKYSQMVAVRDRRQSFIRSVVRFMKQYNFDGFDLDWEYPGATDRGGNYGDKDKFLYFVEELRRAFDREGRGWEITMAVPVAKFRLNEGYHVPELCEALDAIHAMTYDLRGNWAGFADVHSPLYKRKHDQYAYEKLNVNDGLALWEEMGCPANKLVVGVPFYGRTFTLSNSNKNYNMGTYINKEAGGGAPGPYTNASGFLAYYEICTEVMDKSKGWTVEWDDAGMVPYTYKDTQWVGYENEASIQIKMDFIKQRGYAGAMTWAIDMDDFHGMCGRKNGLTQILYDNMKNYRVPEPTRQTTPRPEWAKPPATPPNPDEGAVVAPTTSTTKRPKPKPKPTSSPLSPTSAPGPVPTVGSSTPKPTTKKPKKPKKTTTTTTTTPAPEKSTEEPEEVVYPVDPVEPTDPEQPMGPQFDPNEIDCTNRDFVPHPNCRKYFRCVHGKPVEFECKEGTAFHTVLNVCDWIENSDRYYCSRMKNKEKGNEAH", "length": 595 }, "evidence": [ { "id": "RGD:1303058", "url": "https://alliancegenome.org/gene/RGD:1303058#orthology", "database": "AGR" }, { "id": "MGI:2676649", "url": "https://alliancegenome.org/gene/MGI:2676649#orthology", "database": "AGR" }, { "id": "MGI:1330860", "url": "https://alliancegenome.org/gene/MGI:1330860#orthology", "database": "AGR" }, { "id": "MGI:1341098", "url": "https://alliancegenome.org/gene/MGI:1341098#orthology", "database": "AGR" }, { "id": "MGI:1932052", "url": "https://alliancegenome.org/gene/MGI:1932052#orthology", "database": "AGR" }, { "id": "HGNC:17432", "url": "https://alliancegenome.org/gene/HGNC:17432#orthology", "database": "AGR" }, { "id": "RGD:1308790", "url": "https://alliancegenome.org/gene/RGD:1308790#orthology", "database": "AGR" }, { "id": "RGD:1309110", "url": "https://alliancegenome.org/gene/RGD:1309110#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VZV2-1", "protein_name": "3.2.1.14", "gene_name": "Cht7", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFPPRLLRIAFVICLLIVLLSPSADSAQTKTRRRLRRPTTSVSSSRSNLIESKKSTEAPEAEKRIDQITSATTTSARRTRLRSKAKLGAAAAGGAAVAAGGTALVASGSSLKGKKTKVDDGTPKIVCYYTNWSQYRVKIGKFVPEDIPADLCTHIIFAFGWLKKNKLSSYESNDETKDNVPGLYERMMTLKKANPKLKILLALGGWSFGTQKFKDMSSTRYTRQTFVYSAIPFLRKRGFDGLDMDWEYPKGSDDKKNFVLLLKELREAFEAEAQELKKPRLLLSAAVPVGPDNIRGGYDVPAIASYLDFINLMAYDFHGKWERETGHNAPLYAPSTDSEWRKQLSVDNAASLWVKMGAPKEKLVIGMPTYGRSFTLANPDKHGPNAPASGGGREGVYTKEGGFLAYYEICEMLLNGAVYVWDDEMKVPYLVDGDQWVGFDDERAIRNKMHWIKSNGFGGAMVWTIDMDDFKGEVCGGNVKYPLIGAMREELLGISRGKEAKDVNWTAVAATFEDIEEKPEPIKISVDEILNKVRKPQVQKKQRIKSGANAVASNTRPAQVFCYLTSWSAKRPGAGKFQPENIDPKLCTHIVYAFATLQDYKLTEATDDDPENYESVIALRDNNPDLQILLAIGGWAFGSTPFKELTSNVFRMNQFVYEAIDFLRDYKFNGLDVDWEYPRGAEDRVAYVSLLKELRVAFEGEAKSSGLPRLLLTAAVPASFEAIAAGYDVPEISKYLDFINVMTYDFHGQWERTVGHNSPLFALESATGYQKKLTVDYSAREWVKQGAPKEKLLIGMPTYGRSFELVNDTQFDIGSPSSGGGKAGKFTNEAGFLSYYEVCSFLAADNTTLVWDSEQQVPFAYRGNQWVGFDDERSLKTKTEWLKEQGFGGIMVWSIDMDDFSGRCGSGKYPLLTALNDELKDYKVELEYDGPYESHGPRGAYTTKDPHDVTCAEEDGHISYHKDWADCTHYYMCEGERKHHMPCPANLVFNPQENVCDWPENVEGCHTPTEAPA", "length": 1013 }, "evidence": [ { "id": "MGI:1919134", "url": "https://alliancegenome.org/gene/MGI:1919134#orthology", "database": "AGR" }, { "id": "MGI:2676649", "url": "https://alliancegenome.org/gene/MGI:2676649#orthology", "database": "AGR" }, { "id": "MGI:1330860", "url": "https://alliancegenome.org/gene/MGI:1330860#orthology", "database": "AGR" }, { "id": "MGI:1341098", "url": "https://alliancegenome.org/gene/MGI:1341098#orthology", "database": "AGR" }, { "id": "MGI:1932052", "url": "https://alliancegenome.org/gene/MGI:1932052#orthology", "database": "AGR" }, { "id": "HGNC:17432", "url": "https://alliancegenome.org/gene/HGNC:17432#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-140106-118", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140106-118#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W092-1", "protein_name": "Probable chitinase 2", "gene_name": "Cht2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTLRSRLSGEAPQLWLLLLLASTASSLWASVAARTGPLHDKVVVCYVSTWAVYRPEQGAYAIENFDPNLCTHVVYAFAGLDITQAAIKSLDPWQDLKEEYGKGGYEKMTGLKRSHPHLKVSLAIGGWNEGSANYSTLVANNLLRGRFVKQVSSFIRKYNFDGLDLDWEYPTQRKGKPADRENFVLLTKELREEFDEHGLLLTSAIGASKKVIDEAYDVRQISRYLDYLHIMCYDYHGSWDRRVGYNAPLTAPADDPLSVKFSIDYLLKLGAPPEKLVMGLPFYGRTFKTLASGFLNDVSEGVGFKGPYTREDGFLGYNEICQTLSNQTSGWTREWDPQTSQVLAKSERNVFTQEINVVTYDSSRSIANKVLFAMSKRLAGVMVWSVDTDDFLGNCKLDEDTYEDFQKVTAAPKRSSQNYPLLRTINEATMLAVDELAVPEPQPDDSENEIPHGSIADRKNAGASMVSLGLGVTAVFMLLHRLAQ", "length": 484 }, "evidence": [ { "id": "RGD:1303058", "url": "https://alliancegenome.org/gene/RGD:1303058#orthology", "database": "AGR" }, { "id": "MGI:2676649", "url": "https://alliancegenome.org/gene/MGI:2676649#orthology", "database": "AGR" }, { "id": "MGI:1330860", "url": "https://alliancegenome.org/gene/MGI:1330860#orthology", "database": "AGR" }, { "id": "MGI:1341098", "url": "https://alliancegenome.org/gene/MGI:1341098#orthology", "database": "AGR" }, { "id": "MGI:1932052", "url": "https://alliancegenome.org/gene/MGI:1932052#orthology", "database": "AGR" }, { "id": "HGNC:17432", "url": "https://alliancegenome.org/gene/HGNC:17432#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-140106-118", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140106-118#orthology", "database": "AGR" }, { "id": "RGD:1308790", "url": "https://alliancegenome.org/gene/RGD:1308790#orthology", "database": "AGR" }, { "id": "RGD:1309110", "url": "https://alliancegenome.org/gene/RGD:1309110#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W2M5-1", "protein_name": "3.2.1.14", "gene_name": "Cht9", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGKLLALLAVLCLSQVIGAERIVNCYWGTWANYRSGNGKFDVSNIDAGLCTHLSYSFFGINDNGEIQSLDTWLDYDLGFINQAISLKNQNSNLKVLAVVGGWNEGSTKYSSMSGDWYKRQNFINSALNLLRNHGFDGLDLDWEYPNQRGGNWNDRANFVTLLREIKEAFAPYGYELGIAVGAGESLASASYEIANIAQQVDFINVMTYDFAMASDGQTGFNAPQWAVENAINFWLSQGAPANKLVLGVGTYGRSFQLSDSSQNWPGAPCRGEGSAGSYTGSTGYLGYNEICQNNWHTVFDYDNAAPYAYSGDQWVSFDNVLSVQYKMDFALSKGLAGAMIWSLETDDYRGQCGETYPLLKTINRKLRW", "length": 368 }, "evidence": [ { "id": "RGD:1303058", "url": "https://alliancegenome.org/gene/RGD:1303058#orthology", "database": "AGR" }, { "id": "MGI:1919134", "url": "https://alliancegenome.org/gene/MGI:1919134#orthology", "database": "AGR" }, { "id": "MGI:2676649", "url": "https://alliancegenome.org/gene/MGI:2676649#orthology", "database": "AGR" }, { "id": "MGI:1330860", "url": "https://alliancegenome.org/gene/MGI:1330860#orthology", "database": "AGR" }, { "id": "MGI:1341098", "url": "https://alliancegenome.org/gene/MGI:1341098#orthology", "database": "AGR" }, { "id": "MGI:1932052", "url": "https://alliancegenome.org/gene/MGI:1932052#orthology", "database": "AGR" }, { "id": "HGNC:17432", "url": "https://alliancegenome.org/gene/HGNC:17432#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-140106-118", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140106-118#orthology", "database": "AGR" }, { "id": "RGD:1308790", "url": "https://alliancegenome.org/gene/RGD:1308790#orthology", "database": "AGR" }, { "id": "RGD:1309110", "url": "https://alliancegenome.org/gene/RGD:1309110#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W2M7-1", "protein_name": "chitinase", "gene_name": "Cht8", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MWSVSGLVKLLLGVILMAASSSAQGNSSKNVVCYQGTWSVYRPGLGKFGMEDIDPFLCTHLIYAFLGIEETGQLRVIDAYLDLEENSGRGNIKSFNALKLKNPVLKTLVAVGGWNEGSKRFSLVARDPSKREKFVDDVVRFLQRHGFDGLDLDWEYPGQRHSLDNEDRSNYITFLKELKEGLEPFGFILSAAVGSAQFSAEISYDIPAMVPYLDLINVMAYDLHGPWDQVVGINAPLYAAEKDASDSSGRQQQLNVDAVVKYWLKAGAPAEKLILGVPFYGRSFTLATAEGNQPGAPHIGKGIAGNYSREPGVLGYNELCEMMEREEWTQKWEATQQVPYAYRQRQWVGYEDPRSLALKAQYVMDNHLGGIMIWSLESDDFRGTCGQQPYPLLHEINRVLFGGNTPSGLTTESNRESPSEGFSCPADAPAGYIRDPDNCSKFYYCSGGKTHNFDCPSGLNFDLDTKSCNYSGSVKC", "length": 476 }, "evidence": [ { "id": "RGD:1303058", "url": "https://alliancegenome.org/gene/RGD:1303058#orthology", "database": "AGR" }, { "id": "MGI:1919134", "url": "https://alliancegenome.org/gene/MGI:1919134#orthology", "database": "AGR" }, { "id": "MGI:2676649", "url": "https://alliancegenome.org/gene/MGI:2676649#orthology", "database": "AGR" }, { "id": "MGI:1330860", "url": "https://alliancegenome.org/gene/MGI:1330860#orthology", "database": "AGR" }, { "id": "MGI:1341098", "url": "https://alliancegenome.org/gene/MGI:1341098#orthology", "database": "AGR" }, { "id": "MGI:1932052", "url": "https://alliancegenome.org/gene/MGI:1932052#orthology", "database": "AGR" }, { "id": "HGNC:17432", "url": "https://alliancegenome.org/gene/HGNC:17432#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-140106-118", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140106-118#orthology", "database": "AGR" }, { "id": "RGD:1308790", "url": "https://alliancegenome.org/gene/RGD:1308790#orthology", "database": "AGR" }, { "id": "RGD:1309110", "url": "https://alliancegenome.org/gene/RGD:1309110#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W303-1", "protein_name": "Chitinase-like protein Idgf4", "gene_name": "Idgf4", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKLYALFSLLVGSLAIGQISAAGSHHLLCYYDGNSFVREGLSKLILTDLEPALQYCTHLVYGYAGINPSSNKLVSNNEKLDLDLGSSLFRQVTGLKRKYPALKVLLSVGGDKDTVDPENNKYLTLLESSNARIPFINSAHSLVKTYGFDGLDLGWQFPKNKPKKVHGSIGKFWKGFKKIFSGDHVVDEKAEEHKEAFTALVRELKNAFRPDGYILGLSVLPNVNSSLFFDVPAIINNLDYVNLHTYDFQTPERNNEVADFPAPIYELNERNPEFNVNYQVKYWTGNRAPAAKINVGIATYGRAWKLTKDSGLTGLPPVAEADGVAPAGTQTQIPGLLSWPEVCAKLPNPANQHLKGADGPLRKVGDPTKRFGSYAYRSADDSGENGVWVGYEDPDTAAIKAEYVKREGLGGIAVVDLSFDDFRGGCTGHDKFPILRQVKSKL", "length": 442 }, "evidence": [ { "id": "MGI:1919134", "url": "https://alliancegenome.org/gene/MGI:1919134#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-140106-118", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140106-118#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W3V1-1", "protein_name": "3.2.1.14", "gene_name": "Cht11", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGNYEKLDGSSAGRITDELSRKEQRNCSLRTLVCWSALLFSLLCLCLGFIGLGLLGIQTGEVHKVGQRLVCYYASDGTHNLSLLDVPGDLCTHINIGPATLDNATIVLPDTLRQVLQNDTRSFRAAHPQVHLLLWIGGADSGRSFALMVANHAMRKLFLRSLREILRTYPSLDGIDLDWEFPSAYDRERMHLSQLLYEIRTEWRREKRTNDILSLAVAAPEGIAFYAYDIREINLYADYVNLMSYDFHFYREDTPFTGLNAPLYARSQERSLMATFNINYTVQWWLKSGLEPQRLVVGLPTYGHSFTLVNPLNHRIGAPASGYGKCGQLGFTTLTETCECVTKFFKPNLSYDAESCSPYLSALQEWISYENQTSIACKANYVKSLNLGGVMVFSLNTDDLKNSCSIMPNLKYSEKPVFPLTQAIKDILRESL", "length": 432 }, "evidence": [ { "id": "MGI:1919134", "url": "https://alliancegenome.org/gene/MGI:1919134#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-140106-118", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140106-118#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W5U2-1", "protein_name": "Probable chitinase 10", "gene_name": "Cht10", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MHPYVPSVLVVVVLAISVKAHIRVDKLQIHSESNYKPAFIRSAVESIPLDIDAILLLRNSTKPEFGDAFLPLRSAVESIPKLYQSNTSRFRKNPDVRSFVRDSVESLPNDEDGLEHIEIFTKYYNSVSDVAGVDLKSKKLTHVNLDPGTISDKYAAFIARGNSEDYYPKSYRAGSPHQELLKMMNIEHTDKLDRYSDLQHQQSYGALGLANRNDLKMTKKVLCYMSNWAFYRSGEAHFVPEQIDPNLCSAIIYSFASLDPDHLTIREFDSWVDLDNQYYRRVTSLGVPVLIALGGWTDSSGSKYSRLVSDNLKRRVFISSVSSFLLRHGFSGLHLDWNYPKCWQSDCSRGPVTDRPNLTKLLRELRTEFQSVDPKFQLGVAISGYKEIIKEAYDFPALSDIVDYMTVMTYDYHGAWEQKTGHVSPLYGLSSDTYPQYNTNYTMQLLLKMGARREKLVLSIPFYGQSFTLATAHQILAGPGVAASGPGDAGELTKQPGMLAYYEICQRLTKFNWISDRNLNVIFGPFAMLNDQWVGYEDPTSAQAKARYAANNNFAGVAAWTIDLDDFRNLCCNESYPLLRAINRALGRLDSEPPTQPNCKRPTLLATPVPPQMTTISSDGSGGLGQNHDHTTSLPSGQISSSPVSTTITSTFPWWSSTTKRPREPTKTTAQPTHTTILIPAGINPVVQPSNCKSGEFFADSNNCNAYYHCFFAGELQQQFCPSGLHWNNEAKGCDWPSSAQCSLKLDQHLSTSYPNPIQTSKKPETTLKPNKKPSEISTHHQVNSTSSRPQYMRPTILECTEGDYYPHRNCRKYYICVNKALVPSECGGDLHWDGIKKLCDWPENVQCVTSKKYLKIIKSSSANEEDPCKGEKRVPYPGNCSKYLFCLWNRLQASDCPPGLHYNERIGNCDWPAAAKCNPKGSESSEEAELNAMPKPPTPQTPSSHLRPTYPTEKPVPKPRDSHYKVICYFTNWAWYRKGIGRFTPDDINTELCTHVIYGFAVLDYSELVLRTHDSWADVENNFYTRVTSLKSKGIKVSLALGGWNDSQGDKYSRLVRSPMARSRFVRHALEFIEKYGFEGLDLDWEYPVCWQTECNKGSTEEKDGFTAWVQELSEAFRPRGLMLSTAVSPSRKIIDAGYDIPQLSRYFDWIAVMTYDFHGHWDKKTGHVAPLYHHPDDDFEYFNVNYSINYWMEKGAPSQKLVMGIPLYGQSFTLENTNSSGLNAKAPAPGEAGEFTRAAGFLAYYEICERVNRQGWQVVHDEFGRMGPYAYKGTQWVSYDSPDMVRKKSLLVRSLKLGGGMVWALDLDDFKNRCGNGVHPLLTEIHNVLKDPPSLMEIPGPIETTPTEYPGMEEEIHESNGEGPEVQPIEAVMQTCENEGEEHEGILDPNHVLEEENIEATEMATEFKIICYFTNWAWYRQGGGKFLPEDIDSDLCTHIIYGFAVLSRDNLTIQPHDSWADLDNKFYERIVAYRKKGAKVTVAIGGWNDSAGDKYSRLVRNPEARSRFIRNVLDFIEEYNFDGLDLDWEYPVCWQVDCKKGTAEEKIGFSALVRELFYAFQPRGLILSAAVSPNKKVIDAGYEVAELSHYFSWISVMAYDYHGQWDKKTGHVAPMYSHPEGTANFNANFSMNYWISMGADRRKLVMGIPLYGQSFSLAETTKHQLNAPTYGGGEAGEATRARGFLAYYEICLKIRHHRWNVVRDTKGRIGPFAYHGDQWVSFDDVPMIRHKSEYIKAMGLGGAMIWALDLDDFKNVCECESYPLLKAINRVLRGFGGPQPKCLLENPKSTMKPNIKPPFRPTINAPSGPNLDSPTQNVSLNVLSIKCHSKNYLAHEWDCTKYYICEHGTYVERSCPLGLQWNKTYCDWPTNVQSSLGSNQRTQEPAVHRPNPTSVITEPPIINNSYKVVCYFTSWAWYRSSQGKFVPEDIDANLCTHLIYGFAVLDSKSLTIKTHDSWTDIDNRFYERVVEYKQRGLRVMLAIGGWNDSLGSKYARLVLNSQSRRRFVASVISFLEQHGFEGLDLAWEFPVCWQVNCNRGNPTEKDGFVALVKELSEAFKENGLILSAAVSPSKMVIDAGYNVFELSPYFDWVAVMTYDFHGHWDMRTGQIAPLFHRGGDENLYLNGNFSIHYWLERGIPNDKLVMGMPMYGQTFTLADQNRRSLNDKTVGPGKAGTFTRADGFLAYYEICEKVVNDDWKVVRDEEGIFGSYAYSGNQWISYDDVTTIRRKSQFIKSLQLGGGMIWALDLDDFRGLCGCGKHPLLRTLSQELLGIPGQKAKDCI", "length": 2286 }, "evidence": [ { "id": "MGI:1919134", "url": "https://alliancegenome.org/gene/MGI:1919134#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-140106-118", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140106-118#orthology", "database": "AGR" }, { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9WTV1-1", "protein_name": "Chitinase-3-like protein 1", "gene_name": "Chi3l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTLQLPGFAVLMLLQSCSAYKLVCYYTNWSQYREGNGSCFPDALDHSLCTHIIYSFANISNNKLSTSEWNDVTLYGMLNTLKTRNPRLKTLLSVGGWSFGSERFSRIVSNAKSRKTFVQSVAPFLRTYGFDGLDLAWLYPGPKDKQHFTTLIKELKAEFTKEVQPGTEKLLLSAAVSAGKVTLDSGYDVAQIAQHLDFINLMTYDFHGTWRHTTGHHSPLFRGQQDTGPDRFSNVDYGVGYMLRLGAPTNKLVMGIPTFGKSFTLASSENQVGAPITGSGLPGRYTKEKGTLAYYEICDFLRGAEVHRILGQQVPFATKGNQWVGYDDPESVKNKVKYLKNKQLAGAMVWAVDLDDFRGSFCGHNVHFPLTNAIKEALAVA", "length": 381 }, "evidence": [ { "id": "SGD:S000002779", "url": "https://alliancegenome.org/gene/SGD:S000002779#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q9W2M6", "url": "https://www.uniprot.org/uniprotkb/Q9W2M6" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q9W2M6", "url": "https://www.uniprot.org/uniprotkb/Q9W2M6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "polysaccharide catabolic process", "id": "GO:0000272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000272", "evidence": [ { "database": "UniProtKB", "id": "Q9W2M6", "url": "https://www.uniprot.org/uniprotkb/Q9W2M6" } ], "pmid": "" }, { "name": "chitin catabolic process", "id": "GO:0006032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006032", "evidence": [ { "database": "UniProtKB", "id": "Q9W2M6", "url": "https://www.uniprot.org/uniprotkb/Q9W2M6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "chitinase activity", "id": "GO:0004568", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004568", "evidence": [ { "database": "UniProtKB", "id": "Q9W2M6", "url": "https://www.uniprot.org/uniprotkb/Q9W2M6" } ], "pmid": "" }, { "name": "endochitinase activity", "id": "GO:0008843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008843", "evidence": [ { "database": "UniProtKB", "id": "Q9W2M6", "url": "https://www.uniprot.org/uniprotkb/Q9W2M6" } ], "pmid": "" }, { "name": "chitin binding", "id": "GO:0008061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008061", "evidence": [ { "database": "UniProtKB", "id": "Q9W2M6", "url": "https://www.uniprot.org/uniprotkb/Q9W2M6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-DME-6786421", "name": "CHIA hydrolyses chitin", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region", "input_participant_list": [ "R-ALL-6786438" ], "output_participant_list": [ "R-ALL-6786426", "R-ALL-6786428" ], "enzyme_list": [ "Q9W5U2-1", "M9NDS9-1", "Q9W2M5-1", "Q8MLW8-1", "Q9W2M7-1", "Q9W092-1", "Q9W3V1-1", "Q9VFR3-1", "Q9VZV2-1", "Q9W2M6-1" ], "evidence": [ { "id": "R-DME-6786421", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6786421" } ] }, { "id": "R-DME-6786652", "name": "CHIT1 hydrolyses CHIT to 3xADGP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region", "input_participant_list": [ "R-ALL-6786654" ], "output_participant_list": [ "R-ALL-6786660" ], "enzyme_list": [ "Q9W5U2-1", "M9NDS9-1", "Q9W2M5-1", "Q8MLW8-1", "Q9W2M7-1", "Q9W092-1", "Q9W3V1-1", "Q9VFR3-1", "Q9VZV2-1", "Q9W2M6-1" ], "evidence": [ { "id": "R-DME-6786652", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6786652" } ] }, { "id": "R-DME-6798745", "name": "Exocytosis of tertiary granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, tertiary granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q8INK6-1", "A1Z9D5-1", "A1ZBX6-1", "C0HK98-1", "C0HK99-1", "P29349-4", "Q9VV96-1", "Q9W5U2-1", "M9NDS9-1", "Q9W2M5-1", "P29615-1", "Q9V4X2-1", "Q9VYX7-1", "Q8MLW8-1", "Q9W2M7-1", "A1ZBX7-1", "Q9VBF5-1", "Q9VLR2-1", "Q9W122-1", "Q9W4C2-1", "Q7KRU8-1", "P07764-1", "Q8MPP3-1", "Q9W092-1", "B7Z0E0-1", "Q86PD7-1", "Q9W3V1-1", "A1ZAB8-1", "Q8IQM9-1", "Q9VJ39-1", "P37159-1", "P37160-1", "P37161-1", "P83972-1", "Q08694-1", "Q70PY2-1", "Q9VSA5-1", "Q9VUY9-1", "Q9VFR3-1", "Q9VGN8-1", "Q9VHE4-1", "Q9VYH1-1", "Q9VZV2-1", "Q9W2M6-1" ], "evidence": [ { "id": "R-DME-6798745", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6798745" } ] }, { "id": "R-DME-6798749", "name": "Exocytosis of specific granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, specific granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q8INK6-1", "A1Z9D5-1", "A1ZBX6-1", "Q7KUC2-1", "C0HK98-1", "C0HK99-1", "P29349-4", "Q9VV96-1", "Q9W5U2-1", "M9NDS9-1", "Q9W2M5-1", "P29615-1", "Q9V4X2-1", "Q9V9J3-1", "Q9VYX7-1", "Q8MLW8-1", "Q9W2M7-1", "A1ZBX7-1", "O76895-1", "Q9W122-1", "Q9W4C2-1", "Q8MPP3-1", "Q9W092-1", "Q86PD7-1", "Q9W3V1-1", "A1ZAB8-1", "Q8IQM9-1", "P37159-1", "P37160-1", "P37161-1", "P83972-1", "Q08694-1", "Q70PY2-1", "Q9VSA5-1", "Q9VFR3-1", "Q9VGN8-1", "Q9VHE4-1", "Q9VZV2-1", "Q9W2M6-1" ], "evidence": [ { "id": "R-DME-6798749", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6798749" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-6786426", "participant_name": "GlcNAc-beta1,4-GlcNAc-beta1,4-GlcNAc [extracellular region]", "crossref": [ { "id": "86362", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-6786428", "participant_name": "GlcNAc-beta1,4-GlcNAc [extracellular region]", "crossref": [ { "id": "86361", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-6786438", "participant_name": "chitin [extracellular region]", "crossref": [ { "id": "17029", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-6786654", "participant_name": "CHIT [extracellular region]", "crossref": [ { "id": "84373", "database": "ChEBI", "url": "" }, { "id": "ZINC000056870823", "database": "ZINC", "url": "" }, { "id": "ZINC000070665912", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-6786660", "participant_name": "ADGP [extracellular region]", "crossref": [ { "id": "47977", "database": "ChEBI", "url": "" }, { "id": "G80384UV", "database": "GlyTouCan", "url": "" }, { "id": "ZINC000003860468", "database": "ZINC", "url": "" }, { "id": "HMDB0001514", "database": "HMDB Metabolite", "url": "" }, { "id": "ZINC000003860469", "database": "ZINC", "url": "" }, { "id": "C00329", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A1Z9D5", "gene_name": "Dmel\\CG30062", "activity": [ { "ec_number": "3.2.1.17", "activity": "Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.", "evidence": [ { "id": "A1Z9D5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1Z9D5" } ] }, { "ec_number": "3.2.1.17", "activity": "", "evidence": [ { "id": "A1Z9D5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1Z9D5" } ] } ] }, { "uniprot_ac": "A1ZAB8", "gene_name": "Dmel\\CG7798", "activity": [ { "ec_number": "3.2.1.17", "activity": "Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.", "evidence": [ { "id": "A1ZAB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1ZAB8" } ] }, { "ec_number": "3.2.1.17", "activity": "", "evidence": [ { "id": "A1ZAB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1ZAB8" } ] } ] }, { "uniprot_ac": "A1ZBX6", "gene_name": "Dmel\\CG16799", "activity": [ { "ec_number": "3.2.1.17", "activity": "Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.", "evidence": [ { "id": "A1ZBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1ZBX6" } ] }, { "ec_number": "3.2.1.17", "activity": "", "evidence": [ { "id": "A1ZBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1ZBX6" } ] } ] }, { "uniprot_ac": "A1ZBX7", "gene_name": "Dmel\\CG11159", "activity": [ { "ec_number": "3.2.1.17", "activity": "Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.", "evidence": [ { "id": "A1ZBX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1ZBX7" } ] }, { "ec_number": "3.2.1.17", "activity": "", "evidence": [ { "id": "A1ZBX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1ZBX7" } ] } ] }, { "uniprot_ac": "B7Z0E0", "gene_name": "Idh", "activity": [ { "ec_number": "1.1.1.42", "activity": "D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH.", "evidence": [ { "id": "B7Z0E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B7Z0E0" } ] }, { "ec_number": "1.1.1.42", "activity": "", "evidence": [ { "id": "B7Z0E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B7Z0E0" } ] } ] }, { "uniprot_ac": "C0HK98", "gene_name": "PGRP-SC1a", "activity": [ { "ec_number": "3.5.1.28", "activity": "Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides.", "evidence": [ { "id": "C0HK98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/C0HK98" } ] }, { "ec_number": "3.5.1.28", "activity": "", "evidence": [ { "id": "C0HK98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/C0HK98" } ] } ] }, { "uniprot_ac": "C0HK99", "gene_name": "PGRP-SC1b", "activity": [ { "ec_number": "3.5.1.28", "activity": "Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides.", "evidence": [ { "id": "C0HK99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/C0HK99" } ] }, { "ec_number": "3.5.1.28", "activity": "", "evidence": [ { "id": "C0HK99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/C0HK99" } ] } ] }, { "uniprot_ac": "M9NDS9", "gene_name": "Cht6", "activity": [ { "ec_number": "3.2.1.14", "activity": "Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins.", "evidence": [ { "id": "M9NDS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9NDS9" } ] }, { "ec_number": "3.2.1.14", "activity": "", "evidence": [ { "id": "M9NDS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9NDS9" } ] } ] }, { "uniprot_ac": "O76895", "gene_name": "Arg", "activity": [ { "ec_number": "3.5.3.1", "activity": "L-arginine + H2O = urea + L-ornithine.", "evidence": [ { "id": "O76895", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O76895" } ] }, { "ec_number": "3.5.3.1", "activity": "", "evidence": [ { "id": "O76895", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O76895" } ] } ] }, { "uniprot_ac": "P07764", "gene_name": "Aldo", "activity": [ { "ec_number": "4.1.2.13", "activity": "beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate.", "evidence": [ { "id": "P07764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P07764" } ] }, { "ec_number": "4.1.2.13", "activity": "", "evidence": [ { "id": "P07764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P07764" } ] } ] }, { "uniprot_ac": "P29349", "gene_name": "csw", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "P29349", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P29349" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "P29349", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P29349" } ] } ] }, { "uniprot_ac": "P29615", "gene_name": "LysP", "activity": [ { "ec_number": "3.2.1.17", "activity": "Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.", "evidence": [ { "id": "P29615", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P29615" } ] }, { "ec_number": "3.2.1.17", "activity": "", "evidence": [ { "id": "P29615", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P29615" } ] } ] }, { "uniprot_ac": "P37159", "gene_name": "LysE", "activity": [ { "ec_number": "3.2.1.17", "activity": "Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.", "evidence": [ { "id": "P37159", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P37159" } ] }, { "ec_number": "3.2.1.17", "activity": "", "evidence": [ { "id": "P37159", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P37159" } ] } ] }, { "uniprot_ac": "P37160", "gene_name": "LysS", "activity": [ { "ec_number": "3.2.1.17", "activity": "Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.", "evidence": [ { "id": "P37160", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P37160" } ] }, { "ec_number": "3.2.1.17", "activity": "", "evidence": [ { "id": "P37160", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P37160" } ] } ] }, { "uniprot_ac": "P37161", "gene_name": "LysX", "activity": [ { "ec_number": "3.2.1.17", "activity": "Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.", "evidence": [ { "id": "P37161", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P37161" } ] }, { "ec_number": "3.2.1.17", "activity": "", "evidence": [ { "id": "P37161", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P37161" } ] } ] }, { "uniprot_ac": "P83972", "gene_name": "LysD", 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characterized by hypotonia, seizures, severe intellectual and developmental disability, eye abnormalities and early death and has_material_basis_in mutations in multiple genes including POMT1, POMT2, ISPD, FKTN, FKRP, and LARGE1." }, "synonyms": [ { "id": "DOID:0050560", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050560", "name": "HARD syndrome", "description": "" }, { "id": "DOID:0050560", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050560", "name": "cerebroocular dysplasia-muscular dystrophy syndrome", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "0050560", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050560" } ] }, { "disease_id": "DOID:0050588", "recommended_name": { "id": "DOID:0050588", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050588", "name": "muscular dystrophy-dystroglycanopathy type B1", "description": "A congenital muscular dystrophy characterized by muscle weakness, cognitive impairment and brain abnormalities and has_material_basis_in mutation to the POMT1 gene that encodes O-mannosyltransferase." }, "synonyms": [ { "id": "DOID:0050588", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050588", "name": "CMD due to dystroglycanopathy", "description": "" }, { "id": "DOID:0050588", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050588", "name": "Muscular dystrophy-dystroglycanopathy congenital with impaired intellectual development B1", "description": "" }, { "id": "MONDO:0013159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013159", "name": "muscular dystrophy-dystroglycanopathy (congenital with intellectual disability), type B1", "description": "" }, { "id": "MONDO:0013159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013159", "name": "congenital muscular dystrophy-POMT1 related", "description": "" }, { "id": "MONDO:0013159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013159", "name": "MDDGB1", "description": "" }, { "id": "MONDO:0013159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013159", "name": "muscular dystrophy-dystroglycanopathy (congenital with intellectual disability), type B, 1", "description": "" }, { "id": "MONDO:0013159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013159", "name": "muscular dystrophy-dystroglycanopathy (congenital with mental retardation), type B, 1", "description": "" }, { "id": "MIM:613155", "resource": "MIM", "url": "https://www.omim.org/entry/613155", "name": "Muscular dystrophy-dystroglycanopathy congenital with impaired intellectual development B1", "description": "Muscular dystrophy-dystroglycanopathy congenital with impaired intellectual development B1" } ], "unlinked_id_list": [], "evidence": [ { "id": "0050588", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050588" } ] }, { "disease_id": "DOID:0110299", "recommended_name": { "id": "DOID:0110299", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110299", "name": "autosomal recessive limb-girdle muscular dystrophy type 2I", "description": "An autosomal recessive limb-girdle muscular dystrophy that has_material_basis_in homozygous or compound heterozygous mutation in the gene encoding fukutin-related protein (FKRP) on chromosome 19q13.3." }, "synonyms": [ { "id": "DOID:0110299", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110299", "name": "LGMD2I", "description": "" }, { "id": "DOID:0110299", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110299", "name": "MDDGC5", "description": "" }, { "id": "DOID:0110299", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110299", "name": "muscular dystrophy limb-girdle type 2I", "description": "" }, { "id": "DOID:0110299", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110299", "name": "muscular dystrophy-dystroglycanopathy limb-girdle FRKP-related", "description": "" }, { "id": "DOID:0110299", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110299", "name": "Limb-girdle muscular dystrophy due to FKRP deficiency", "description": "" }, { "id": "DOID:0110299", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110299", "name": "muscular dystrophy-dystroglycanopathy (limb-girdle) type C 5", "description": "" }, { "id": "MONDO:0011787", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011787", "name": "autosomal recessive limb-girdle muscular dystrophy type 2I", "description": "A subtype of autosomal recessive limb-girdle muscular dystrophy that presents a highly variable age of onset and phenotypic spectrum typically characterized by slowly progressive proximal weakness of the pelvic and shoulder girdle musculature (predominantly affecting the lower limbs), frequently associated with waddling gait, scapular winging, calf and tongue hypertrophy, exercise-induced myalgia, and myoglobinuria and/or elevated creatine kinase serum levels. Abdominal muscle weakness, cardiomyopathy, respiratory muscle involvement and various brain abnormalities have also been reported." }, { "id": "MONDO:0011787", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011787", "name": "FKRP autosomal recessive limb-girdle muscular dystrophy", "description": "" }, { "id": "MONDO:0011787", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011787", "name": "LGMD-FKRP related", "description": "" }, { "id": "MONDO:0011787", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011787", "name": "LGMD2I", "description": "" }, { "id": "MONDO:0011787", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011787", "name": "MDDGC5", "description": "" }, { "id": "MONDO:0011787", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011787", "name": "autosomal recessive limb-girdle muscular dystrophy caused by mutation in FKRP", "description": "" }, { "id": "MONDO:0011787", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011787", "name": "limb-girdle muscular dystrophy due to FKRP deficiency", "description": "" }, { "id": "MONDO:0011787", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011787", "name": "muscular dystrophy-dystroglycanopathy (Limb-girdle) type C, 5", "description": "" }, { "id": "MONDO:0011787", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011787", "name": "muscular dystrophy-dystroglycanopathy (limb-girdle), type C5", "description": "" }, { "id": "MONDO:0011787", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011787", "name": "limb-girdle muscular dystrophy type 2I", "description": "" }, { "id": "MONDO:0011787", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011787", "name": "muscular dystrophy-dystroglycanopathy (limb-girdle), type C, 5", "description": "" }, { "id": "MIM:607155", "resource": "MIM", "url": "https://www.omim.org/entry/607155", "name": "Muscular dystrophy-dystroglycanopathy limb-girdle C5", "description": "Muscular dystrophy-dystroglycanopathy limb-girdle C5" } ], "unlinked_id_list": [], "evidence": [ { "id": "0110299", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110299" } ] }, { "disease_id": "DOID:0110635", "recommended_name": { "id": "DOID:0110635", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110635", "name": "muscular dystrophy-dystroglycanopathy type B5", "description": "A congenital muscular dystrophy characterized by autosomal recessive inheritance of muscular dystrophy with variable penetrance of intellectual disability and structural brain abnormalities that has_material_basis_in homozygous or compound heterozygous mutation in the FKRP gene on chromosome 19q13.3." }, "synonyms": [ { "id": "DOID:0110635", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110635", "name": "FKRP-related congenital muscular dystrophy", "description": "" }, { "id": "DOID:0110635", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110635", "name": "MDC1C", "description": "" }, { "id": "DOID:0110635", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110635", "name": "MDDGB5", "description": "" }, { "id": "DOID:0110635", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110635", "name": "congenital muscular dystrophy 1C", "description": "" }, { "id": "DOID:0110635", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110635", "name": "muscular dystrophy-dystroglycanopathy (congenital with or without mental retardation), type B, 5", "description": "" }, { "id": "DOID:0110635", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110635", "name": "muscular dystrophy-dystroglycanopathy (congenital with or without impaired intellectual development), type B, 5", "description": "" }, { "id": "MONDO:0011688", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011688", "name": "muscular dystrophy-dystroglycanopathy type B5", "description": "A congenital muscular dystrophy characterized by autosomal recessive inheritance of muscular dystrophy with variable penetrance of intellectual disability and structural brain abnormalities that has material basis in homozygous or compound heterozygous mutation in the FKRP gene on chromosome 19q13.3." }, { "id": "MONDO:0011688", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011688", "name": "MDC1C", "description": "" }, { "id": "MONDO:0011688", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011688", "name": "MDDGB5", "description": "" }, { "id": "MONDO:0011688", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011688", "name": "congenital muscular dystrophy-FKRP related", "description": "" }, { "id": "MONDO:0011688", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011688", "name": "muscular dystrophy-dystroglycanopathy (congenital with or without intellectual disability), type B, 5", "description": "" }, { "id": "MONDO:0011688", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011688", "name": "muscular dystrophy-dystroglycanopathy (congenital with or without mental retardation), type B, 5", "description": "" }, { "id": "MIM:606612", "resource": "MIM", "url": "https://www.omim.org/entry/606612", "name": "Muscular dystrophy-dystroglycanopathy congenital with or without impaired intellectual development B5", "description": "Muscular dystrophy-dystroglycanopathy congenital with or without impaired intellectual development B5" } ], "unlinked_id_list": [], "evidence": [ { "id": "0110635", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110635" } ] }, { "disease_id": "DOID:0111241", "recommended_name": { "id": "DOID:0111241", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111241", "name": "congenital muscular dystrophy-dystroglycanopathy type A5", "description": "A congenital muscular dystrophy-dystroglycanopathy type A that has_material_basis_in homozygous or compound heterozygous mutation in FKRP on 19q13.32." }, "synonyms": [ { "id": "DOID:0111241", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111241", "name": "congenital muscular dystrophy-dystroglycanopathy with brain and eye anomalies type A5", "description": "" }, { "id": "DOID:0111241", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111241", "name": "MDDGA5", "description": "" }, { "id": "DOID:0111241", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111241", "name": "Walker-Warburg syndrome or muscle-eye-brain disease, FKRP-related", "description": "" }, { "id": "MONDO:0013157", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013157", "name": "muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A5", "description": "" }, { "id": "MONDO:0013157", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013157", "name": "muscle-eye-brain-FKRP related", "description": "" }, { "id": "MONDO:0013157", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013157", "name": "MDDGA5", "description": "" }, { "id": "MONDO:0013157", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013157", "name": "muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A, 5", "description": "" }, { "id": "MIM:613153", "resource": "MIM", "url": "https://www.omim.org/entry/613153", "name": "Muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies A5", "description": "Muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies A5" } ], "unlinked_id_list": [], "evidence": [ { "id": "0111241", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111241" } ] }, { "disease_id": "DOID:11724", "recommended_name": { "id": "DOID:11724", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11724", "name": "limb-girdle muscular dystrophy", "description": "A muscular dystrophy that is characterized by weakening of the muscles of the hip and shoulders which comprise the limb girdle muscles." }, "synonyms": [ { "id": "DOID:11724", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11724", "name": "Erb's muscular dystrophy", "description": "" }, { "id": "DOID:11724", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11724", "name": "Leyden-Mbius muscular dystrophy", "description": "" }, { "id": "DOID:11724", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11724", "name": "limb girdle muscular dystrophy", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "11724", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11724" } ] }, { "disease_id": "DOID:12930", "recommended_name": { "id": "DOID:12930", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently." }, "synonyms": [ { "id": "DOID:12930", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12930", "name": "primary dilated cardiomyopathy", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "dilated cardiomyopathy 1A", "description": "Familial dilated cardiomyopathy with conduction defect due to LMNA mutation is a rare familial dilated cardiomyopathy characterized by left ventricular enlargement and/or reduced systolic function preceded or accompanied by significant conduction system disease and/or arrhythmias including bradyarrhythmias, supraventricular or ventricular arrhythmias. Disease onset is usually in early to mid-adulthood. Sudden cardiac death may occur and may be the presenting symptom. In some cases, it is associated with skeletal myopathy and elevated serum creatine kinase." }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "CDCD1", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "LMNA familial isolated dilated cardiomyopathy", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "cardiomyopathy dilated with conduction defect type 1", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "cardiomyopathy, dilated, type 1A", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "dilated cardiomyopathy 1A", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "dilated cardiomyopathy type 1A", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "familial dilated cardiomyopathy with conduction defect due to LMNA mutation", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "familial isolated dilated cardiomyopathy caused by mutation in LMNA", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "cardiomyopathy, dilated, 1A", "description": "" }, { "id": "MIM:115200", "resource": "MIM", "url": "https://www.omim.org/entry/115200", "name": "Cardiomyopathy, dilated, 1A", "description": "Cardiomyopathy, dilated, 1A" } ], "unlinked_id_list": [], "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ] }, { "disease_id": "DOID:9884", "recommended_name": { "id": "DOID:9884", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9884", "name": "muscular dystrophy", "description": "A myopathy is characterized by progressive skeletal muscle weakness degeneration." }, "synonyms": [ { "id": "MONDO:0008028", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008028", "name": "muscular dystrophy, Barnes type", "description": "" }, { "id": "MONDO:0008028", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008028", "name": "muscular dystrophy, Barnes type", "description": "" }, { "id": "MONDO:0008034", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008034", "name": "muscular dystrophy, pseudohypertrophic, with Internalized capillaries", "description": "" }, { "id": "MONDO:0008034", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008034", "name": "muscular dystrophy, pseudohypertrophic, with Internalized capillaries", "description": "" }, { "id": "MONDO:0010675", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010675", "name": "muscular dystrophy, cardiac type", "description": "" }, { "id": "MONDO:0010675", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010675", "name": "muscular dystrophy, cardiac type", "description": "" }, { "id": "MONDO:0010676", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010676", "name": "muscular dystrophy, Hemizygous lethal type", "description": "" }, { "id": "MONDO:0010676", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010676", "name": "muscular dystrophy, Hemizygous lethal type", "description": "" }, { "id": "MONDO:0010677", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010677", "name": "muscular dystrophy, Mabry type", "description": "" }, { "id": "MONDO:0010677", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010677", "name": "muscular dystrophy, Mabry type", "description": "" }, { "id": "MONDO:0010678", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010678", "name": "muscular dystrophy, progressive Pectorodorsal", "description": "" }, { "id": "MONDO:0010678", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010678", "name": "muscular dystrophy, progressive Pectorodorsal", "description": "" }, { "id": "MONDO:0010884", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010884", "name": "muscular dystrophy, scapulohumeral", "description": "" }, { "id": "MONDO:0010884", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010884", "name": "muscular dystrophy, scapulohumeral", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "9884", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9884" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W2P2", "url": "https://www.uniprot.org/uniprotkb/Q9W2P2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG15651", "url": "https://www.uniprot.org/uniprotkb/Q9W2P2", "locus": { "chromosome": "2R", "start_pos": 20983838, "end_pos": 20986500, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0034567", "url": "https://www.ensemblgenomes.org/id/FBgn0034567" } ] } } ], "crossref": [ { "id": "FB:FBgn0034567", "url": "https://alliancegenome.org/gene/FB:FBgn0034567", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0034567", "url": "https://bgee.org/?page=gene&gene_id=FBgn0034567", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0034567", "url": "https://flybase.org/reports/FBgn0034567", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "37375", "url": "https://www.ncbi.nlm.nih.gov/gene/37375", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR052613", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052613", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055105", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055105", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG15651", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG15651", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KEWTATY", "url": "https://omabrowser.org/oma/group/KEWTATY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W2P2", "url": "https://www.orthodb.org/?gene=Q9W2P2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13627", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13627", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13627:SF31", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13627:SF31", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF22921", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22921", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_611531", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611531", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W2P2", "url": "https://www.uniprot.org/uniprotkb/Q9W2P2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W2P2-1", "url": "https://www.uniprot.org/uniprotkb/Q9W2P2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKVFRLRLVKLLLLGFLLANLVFLYYTWNTLLWRRISRALSGESQPAEEPPKAAKLSPKEKLRNANKHIRKSITIVFYGHYNFEQDLKASIDSILDVIPNMPILVLQDGGAEYAYPPVNYERNLTAGEERTVLFQSLSFDVRRTRQELNPLASIRTKYALIMPDGVRLNSKNILQKILREINSMGLPGQPKEQRPPVPPEQLVRRMVLVPFAGNLKSFSSCVKMNLDLPDWTLELVATNDTRRCDLFLQKHAILLDAAALAAMPEPFSLPFPEMLYMQAKIANLSTTVFPQAFQEGRRLFASFHTKQRRMDLRRRQFREMYKKLQIKRIVRRAYRVPGKAQAREVWGQGHGLVLDGQFSSSNTSLPLITDIDLFGCERTTKSCIGSVYNERPYYSYLGKHTPPCCLDKLRTTFNHVLEEFENVGIRYWLDNRALQSAIETNHLSPDAYDIDISFNVQDLERSNAMKKSQSKPYVDNEGFYWIKATDGHHFRVQFSKPNQVGVNLLPYSISGTEAKASGFFGWKARSFSADYLHPMSTVLFLGKSVMCPNNVLEYLEEKRIRVKSADLDADED", "length": 572, "header": "tr|Q9W2P2-1|Q9W2P2_DROME Isoform 1 of FKRP stem domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG15651 PE=4 SV=1 CANONICAL=Q9W2P2-1" }, "isoforms": [ { "isoform_ac": "Q9W2P2-1", "url": "https://www.uniprot.org/uniprotkb/Q9W2P2/entry#Q9W2P2-1", "sequence": { "sequence": "MKVFRLRLVKLLLLGFLLANLVFLYYTWNTLLWRRISRALSGESQPAEEPPKAAKLSPKEKLRNANKHIRKSITIVFYGHYNFEQDLKASIDSILDVIPNMPILVLQDGGAEYAYPPVNYERNLTAGEERTVLFQSLSFDVRRTRQELNPLASIRTKYALIMPDGVRLNSKNILQKILREINSMGLPGQPKEQRPPVPPEQLVRRMVLVPFAGNLKSFSSCVKMNLDLPDWTLELVATNDTRRCDLFLQKHAILLDAAALAAMPEPFSLPFPEMLYMQAKIANLSTTVFPQAFQEGRRLFASFHTKQRRMDLRRRQFREMYKKLQIKRIVRRAYRVPGKAQAREVWGQGHGLVLDGQFSSSNTSLPLITDIDLFGCERTTKSCIGSVYNERPYYSYLGKHTPPCCLDKLRTTFNHVLEEFENVGIRYWLDNRALQSAIETNHLSPDAYDIDISFNVQDLERSNAMKKSQSKPYVDNEGFYWIKATDGHHFRVQFSKPNQVGVNLLPYSISGTEAKASGFFGWKARSFSADYLHPMSTVLFLGKSVMCPNNVLEYLEEKRIRVKSADLDADED", "length": 572, "header": "tr|Q9W2P2-1|Q9W2P2_DROME Isoform 1 of FKRP stem domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG15651 PE=4 SV=1 CANONICAL=Q9W2P2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W2P2", "url": "https://www.uniprot.org/uniprotkb/Q9W2P2" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W2P2", "url": "https://www.uniprot.org/uniprotkb/Q9W2P2" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2P2", "url": "https://www.uniprot.org/uniprotkb/Q9W2P2" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2P2", "url": "https://www.uniprot.org/uniprotkb/Q9W2P2" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W2P2", "url": "https://www.uniprot.org/uniprotkb/Q9W2P2" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W2P2", "url": "https://www.uniprot.org/uniprotkb/Q9W2P2" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W2P2", "url": "https://www.uniprot.org/uniprotkb/Q9W2P2" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2P2", "url": "https://www.uniprot.org/uniprotkb/Q9W2P2" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2P2", "url": "https://www.uniprot.org/uniprotkb/Q9W2P2" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W2P2", "url": "https://www.uniprot.org/uniprotkb/Q9W2P2" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W2P2", "url": "https://www.uniprot.org/uniprotkb/Q9W2P2" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG15651", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG15651", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1MET8-1", "protein_name": "Ribitol-5-phosphate transferase", "gene_name": "FKRP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLTRCQAALAAAITLNLLVLFYVSWLHHQPRSSRTRGSRRGSTSGPRVTILVREFEAFDNAVPELVDSFLQQEPTQPVVVVADTLPYPPLALPRIPNVRLALLQPALDRPASASRPETYVATEYVALVPDGARAEAPGQLERMVEVLRAGGARLVAAPIASANPARCLALNVSLREWTAHYGPAPSAPRCDALDGDAVVLLRARDLFNLSAPLARPVGTGLFLQTALRGWTVQMLDLPFGVARQPPLATAHARWKAEREGRARRAALLRALGVRLVSWEGGRLEWFGCNKETPRCFGTVVGDTPAYLYEERWTPPCCLRALRETARYVVGVLEAAGVRYWLEGGSLLGAARHGDIIPWDYDVDLGIYLEDVGNCEQLRGAEAGSVVDERGFVWEKAVEGDFFRVQYSESNHLHVDLWPFYPRNGVMTKDTWLDHRQDVEFPEHFLQPLVPLPFAGFVAQAPNNYRRFLELKFGPGVIENPEYPNPALLSLGGSS", "length": 495 }, "evidence": [ { "id": "Q9W2P2", "url": "https://omabrowser.org/oma/group/Q9W2P2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RM20-1", "protein_name": "Ribitol-5-phosphate transferase", "gene_name": "FKRP", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRLTRCQAALAAAITLNLLVLFYVSWLQHQPRNSRARGSRRGSTSGPRVTVLVREFEAFDNAVPELVDSFLQQDPAQPVVVASDTLPYPPLALPRISNVRLALLQPALDRPAAASRPETYVATEFVALVPDGARAEAPGQLERMVEVLRAGGARLVAAPVASANPARCLALNVSLREWTARYGPAPSAPRCDAVDGDAVVLLRTRDLFNLSAPLARPVGTSLFLQTALRGWTVQLLDAPFAAAHQPPLATAHARWKAEREGRARRAALLQALGIRLVSWEGGRLEWFGCNKETPRCFGTVVGDTPAYLYEGRWTPPCCLRALRETARYVVGVLEAAGVRYWLEGGSLLGAARHGDIIPWDYDVDLGIYLEDVGNCEQLRGAEAGSVVDERGFVWEKAVEGDFFRVQYSESNHLHVDLWPFYPRNGVMTKDTWLDHRQDVEFPEHFLQPLVPLPFAGFVAQAPNNYRRFLELKFGPGVIENPEYPNPALLSLAASS", "length": 495 }, "evidence": [ { "id": "Q9W2P2", "url": "https://omabrowser.org/oma/group/Q9W2P2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q4KLJ4-1", "protein_name": "Ribitol-5-phosphate transferase", "gene_name": "Fkrp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLTRCWAALAAAIILNLLVFFYVSWLQHQPRNSRTRGPRRTSAIGPRVTVLIREFEAFDNAVPELVDSFLQLDPAQPVVVAADTLPYPPLALPRIPNVRLALLQPALDRSAAASRPETYVATEFVALVPDGARAESPGHLERMVEALRGSSARLVAAPVATTNPARCLALNVSLREWTARYGPAPSAPRCDALDGDAVLLMRSRDLFNLSVPLARPLATSLFLQTALRGWAVQLLDLTFASARQPPLATAHARWKAEREGRSRRAALLRSLGIRLVSWEGGRLEWFGCSKESPRCFGTVVGDTPAYLYEGRWTPPCCLRALRETARYVVGVLEAAGVRYWLEGGSLLGAARHGDIIPWDYDVDLGIYLEDVGNCEQLRGAEAGSVVDERGFVWEKAVEGDFFRVQYSESNHLHVDLWPFYPRNGVMTKDTWLDHRQDVEFPEHFLQPLVPLAFAGFMAQAPNNYRRFLELKFGPGVIENPEYPNPALLSLTGG", "length": 494 }, "evidence": [ { "id": "RGD:1305852", "url": "https://alliancegenome.org/gene/RGD:1305852#orthology", "database": "AGR" }, { "id": "MGI:2447586", "url": "https://alliancegenome.org/gene/MGI:2447586#orthology", "database": "AGR" }, { "id": "HGNC:17997", "url": "https://alliancegenome.org/gene/HGNC:17997#orthology", "database": "AGR" }, { "id": "FB:FBgn0034567", "url": 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"resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008197", "name": "parietal foramina 1", "description": "" }, { "id": "MONDO:0008197", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008197", "name": "parietal foramina caused by mutation in MSX2", "description": "" }, { "id": "MONDO:0008197", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008197", "name": "PFM", "description": "" }, { "id": "MONDO:0008197", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008197", "name": "PFM1", "description": "" }, { "id": "MONDO:0008197", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008197", "name": "parietal foramina", "description": "" }, { "id": "MONDO:0012302", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012302", "name": "parietal foramina 3", "description": "" }, { "id": "MONDO:0012302", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012302", "name": "PFM3", "description": "" }, { "id": "MONDO:0012302", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012302", "name": "parietal foramina 3", "description": "" }, { "id": "MONDO:0012309", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012309", "name": "parietal foramina 2", "description": "Any parietal foramina in which the cause of the disease is a mutation in the ALX4 gene." }, { "id": "MONDO:0012309", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012309", "name": "ALX4 parietal foramina", "description": "" }, { "id": "MONDO:0012309", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012309", "name": "parietal foramina 2", "description": "" }, { "id": "MONDO:0012309", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012309", "name": "parietal foramina caused by mutation in ALX4", "description": "" }, { "id": "MONDO:0012309", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012309", "name": "parietal foramina type 2", "description": "" }, { "id": "MONDO:0012309", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012309", "name": "PFM2", "description": "" }, { "id": "MIM:168500", "resource": "MIM", "url": "https://www.omim.org/entry/168500", "name": "Parietal foramina 1", "description": "Parietal foramina 1" }, { "id": "MIM:609597", "resource": "MIM", "url": "https://www.omim.org/entry/609597", "name": "Parietal foramina 2", "description": "Parietal foramina 2" } ], "unlinked_id_list": [], "evidence": [ { "id": "0060285", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060285" } ] }, { "disease_id": "DOID:0060309", "recommended_name": { "id": "DOID:0060309", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0060309", "name": "syndromic X-linked intellectual disability", "description": "A syndromic intellectual disability characterized by an X-linked inheritance pattern." }, "synonyms": [ { "id": "DOID:0060309", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0060309", "name": "syndromic X-linked mental retardation", "description": "" }, { "id": "MONDO:0010654", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010654", "name": "Partington syndrome", "description": "A rare neurological condition that is primarily characterized by mild to moderate intellectual disability and dystonia of the hands. Other signs and symptoms may include dysarthria, behavioral abnormalities, recurrent seizures and/or an unusual gait (style of walking). Partington syndrome usually occurs in males; when it occurs in females, the signs and symptoms are often less severe. It is caused by changes (mutations) in the ARX gene and is inherited in an X-linked recessive manner. Treatment is based on the signs and symptoms present in each person." }, { "id": "MONDO:0010654", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010654", "name": "Partington syndrome", "description": "" }, { "id": "MONDO:0010654", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010654", "name": "Partington syndrome, X-linked recessive", "description": "" }, { "id": "MONDO:0010654", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010654", "name": "Partington-Mulley syndrome", "description": "" }, { "id": "MONDO:0010654", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010654", "name": "X-linked intellectual disability-dystonia-dysarthria syndrome", "description": "" }, { "id": "MONDO:0010654", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010654", "name": "MRXS1", "description": "" }, { "id": "MONDO:0010654", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010654", "name": "PRTS", "description": "" }, { "id": "MONDO:0010654", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010654", "name": "Partington X-linked intellectual disability syndrome", "description": "" }, { "id": "MONDO:0010654", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010654", "name": "Partington X-linked mental retardation syndrome", "description": "" }, { "id": "MONDO:0010654", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010654", "name": "intellectual disability, X-linked, syndromic 1", "description": "" }, { "id": "MONDO:0010654", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010654", "name": "intellectual disability, X-linked, with dystonic movements, ataxia, and seizures", "description": "" }, { "id": "MONDO:0010654", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010654", "name": "intellectual disability-dystonic movements-ataxia-seizures syndrome", "description": "" }, { "id": "MONDO:0010654", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010654", "name": "mental retardation, X-linked 36", "description": "" }, { "id": "MONDO:0010654", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010654", "name": "mental retardation, X-linked, syndromic 1", "description": "" }, { "id": "MONDO:0010654", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010654", "name": "mental retardation, X-linked, with dystonic movements, ataxia, and seizures", "description": "" }, { "id": "MIM:309510", "resource": "MIM", "url": "https://www.omim.org/entry/309510", "name": "Partington syndrome", "description": "Partington syndrome" } ], "unlinked_id_list": [], "evidence": [ { "id": "0060309", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060309" } ] }, { "disease_id": "DOID:0060806", "recommended_name": { "id": "DOID:0060806", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0060806", "name": "syndromic X-linked intellectual disability Hedera type", "description": "A syndromic X-linked intellectual disability characterized by mild to moderate mental retardation and epilepsy that has_material_basis_in mutation in the ATP6AP2 gene on chromosome Xp11." }, "synonyms": [ { "id": "DOID:0060806", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0060806", "name": "mental retardation, X-linked, syndromic, Hedera type", "description": "" }, { "id": "DOID:0060806", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0060806", "name": "MRXE", "description": "" }, { "id": "DOID:0060806", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0060806", "name": "MRXSH", "description": "" }, { "id": "DOID:0060806", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0060806", "name": "X-linked mental retardation with epilepsy", "description": "" }, { "id": "MONDO:0010319", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010319", "name": "syndromic X-linked intellectual disability Hedera type", "description": "X-linked intellectual disability, Hedera type is a rare X-linked intellectual disability syndrome characterized by an onset in infancy of delayed motor and speech milestones, generalized tonic-clonic seizures and drop attacks, and mild to moderate intellectual disability. Additional, less common manifestations include scoliosis, ataxia (resulting in progressive gait disturbance), and bilateral pes planovalgus. Physical appearance is normal with no dysmorphic features reported." }, { "id": "MONDO:0010319", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010319", "name": "MRXE", "description": "" }, { "id": "MONDO:0010319", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010319", "name": "MRXSH", "description": "" }, { "id": "MONDO:0010319", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010319", "name": "X-linked intellectual disability with epilepsy", "description": "" }, { "id": "MONDO:0010319", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010319", "name": "intellectual developmental disorder, X-linked, syndromic, Hedera type, X-linked recessive", "description": "" }, { "id": "MONDO:0010319", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010319", "name": "intellectual disability, X-linked, syndromic, Hedera type", "description": "" }, { "id": "MONDO:0010319", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010319", "name": "mental retardation, X-linked, syndromic, Hedera type", "description": "" }, { "id": "MONDO:0010319", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010319", "name": "mental retardation, X-linked, with epilepsy", "description": "" }, { "id": "MIM:300423", "resource": "MIM", "url": "https://www.omim.org/entry/300423", "name": "Intellectual developmental disorder, X-linked, syndromic, Hedera type", "description": "Intellectual developmental disorder, X-linked, syndromic, Hedera type" } ], "unlinked_id_list": [], "evidence": [ { "id": "0060806", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060806" } ] }, { "disease_id": "DOID:0080468", "recommended_name": { "id": "DOID:0080468", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080468", "name": "developmental and epileptic encephalopathy 1", "description": "A developmental and epileptic encephalopathy characterized by X-linked recessive inheritance of frequent tonic seizures or spasms beginning in infancy that has_material_basis_in mutation in the ARX gene on chromosome Xp21." }, "synonyms": [ { "id": "DOID:0080468", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080468", "name": "X-linked infantile spasm syndrome 1", "description": "" }, { "id": "DOID:0080468", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080468", "name": "DEE1", "description": "" }, { "id": "DOID:0080468", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080468", "name": "early infantile epileptic encephalopathy 1", "description": "" }, { "id": "MONDO:0010632", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010632", "name": "developmental and epileptic encephalopathy, 1", "description": "Any early infantile epileptic encephalopathy in which the cause of the disease is a mutation in the ARX gene." }, { "id": "MONDO:0010632", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010632", "name": "ARX early infantile epileptic encephalopathy", "description": "" }, { "id": "MONDO:0010632", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010632", "name": "DEE1", "description": "" }, { "id": "MONDO:0010632", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010632", "name": "EIEE1", "description": "" }, { "id": "MONDO:0010632", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010632", "name": "developmental and epileptic encephalopathy 1, X-linked recessive", "description": "" }, { "id": "MONDO:0010632", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010632", "name": "early infantile epileptic encephalopathy caused by mutation in ARX", "description": "" }, { "id": "MONDO:0010632", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010632", "name": "early infantile epileptic encephalopathy caused by mutation in arx", "description": "" }, { "id": "MONDO:0010632", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010632", "name": "epileptic encephalopathy, early infantile, 1", "description": "" }, { "id": "MONDO:0010632", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010632", "name": "epileptic encephalopathy, early infantile, type 1", "description": "" }, { "id": "MONDO:0010632", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010632", "name": "XMESID", "description": "" }, { "id": "MIM:308350", "resource": "MIM", "url": "https://www.omim.org/entry/308350", "name": "Developmental and epileptic encephalopathy 1", "description": "Developmental and epileptic encephalopathy 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "0080468", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080468" } ] }, { "disease_id": "DOID:0081045", "recommended_name": { "id": "DOID:0081045", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0081045", "name": "frontonasal dysplasia 1", "description": "A frontonasal dysplasia that is characterized by hypertelorism, wide nasal bridge, broad columella, widened philtrum, widely separated narrow nares, poor development of nasal tip, midline notch of the upper alveolus, columella base swellings and a low hairline, and has_material_basis_in homozygous mutation in the aristaless-like homeobox-3 gene (ALX3) on chromosome 1p13." }, "synonyms": [ { "id": "DOID:0081045", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0081045", "name": "Frontorhiny", "description": "" }, { "id": "MONDO:0007636", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007636", "name": "frontorhiny", "description": "Frontorhiny is a distinct syndromic type of frontonasal malformation characterized by hypertelorism, wide nasal bridge, broad columella, widened philtrum, widely separated narrow nares, poor development of nasal tip, midline notch of the upper alveolus, columella base swellings and a low hairline. Additional features reported in some include upper eyelid ptosis and midline dermoid cysts of craniofacial structures and philtral pits or rugose folding behind the ears. An autosomal recessive inheritance has been proposed." }, { "id": "MONDO:0007636", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007636", "name": "ALX3-related frontonasal dysplasia", "description": "" }, { "id": "MONDO:0007636", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007636", "name": "frontonasal dysplasia type 1", "description": "" }, { "id": "MONDO:0007636", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007636", "name": "frontorhiny", "description": "" }, { "id": "MONDO:0007636", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007636", "name": "isolated median cleft face syndrome", "description": "" }, { "id": "MONDO:0007636", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007636", "name": "FND1", "description": "" }, { "id": "MONDO:0007636", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007636", "name": "frontonasal dysplasia 1", "description": "" }, { "id": "MONDO:0007636", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007636", "name": "isolated median cleft syndrome", "description": "" }, { "id": "MIM:136760", "resource": "MIM", "url": "https://www.omim.org/entry/136760", "name": "Frontonasal dysplasia 1", "description": "Frontonasal dysplasia 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "0081045", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081045" } ] }, { "disease_id": "DOID:0081046", "recommended_name": { "id": "DOID:0081046", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0081046", "name": "frontonasal dysplasia 2", "description": "A frontonasal dysplasia that has_material_basis_in homozygous mutation in the ALX4 gene on chromosome 11p11." }, "synonyms": [ { "id": "MONDO:0013268", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013268", "name": "frontonasal dysplasia with alopecia and genital anomaly", "description": "Frontonasal dysplasia with alopecia and genital anomaly is a new phenotype of frontonasal dysplasia associated with total alopecia and hypogonadism." }, { "id": "MONDO:0013268", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013268", "name": "ALX4-related FNDAG", "description": "" }, { "id": "MONDO:0013268", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013268", "name": "craniofrontonasal dysplasia with alopecia and hypogonadism", "description": "" }, { "id": "MONDO:0013268", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013268", "name": "frontonasal dysplasia type 2", "description": "" }, { "id": "MONDO:0013268", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013268", "name": "frontonasal dysplasia with alopecia and genital abnomality", "description": "" }, { "id": "MONDO:0013268", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013268", "name": "FND2", "description": "" }, { "id": "MONDO:0013268", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013268", "name": "frontonasal dysplasia 2", "description": "" }, { "id": "MIM:613451", "resource": "MIM", "url": "https://www.omim.org/entry/613451", "name": "Frontonasal dysplasia 2", "description": "Frontonasal dysplasia 2" } ], "unlinked_id_list": [], "evidence": [ { "id": "0081046", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081046" } ] }, { "disease_id": "DOID:0081047", "recommended_name": { "id": "DOID:0081047", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0081047", "name": "frontonasal dysplasia 3", "description": "A frontonasal dysplasia that has_material_basis_in homozygous mutation in the ALX1 gene on chromosome 12q21." }, "synonyms": [ { "id": "MONDO:0013271", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013271", "name": "frontonasal dysplasia - severe microphthalmia - severe facial clefting syndrome", "description": "" }, { "id": "MONDO:0013271", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013271", "name": "ALX1-related frontonasal dysplasia", "description": "" }, { "id": "MONDO:0013271", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013271", "name": "frontonasal dysplasia type 3", "description": "" }, { "id": "MONDO:0013271", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013271", "name": "FND3", "description": "" }, { "id": "MONDO:0013271", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013271", "name": "frontonasal dysplasia 3", "description": "" }, { "id": "MIM:613456", "resource": "MIM", "url": "https://www.omim.org/entry/613456", "name": "Frontonasal dysplasia 3", "description": "Frontonasal dysplasia 3" } ], "unlinked_id_list": [], "evidence": [ { "id": "0081047", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081047" } ] }, { "disease_id": "DOID:0112021", "recommended_name": { "id": "DOID:0112021", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0112021", "name": "non-syndromic X-linked intellectual disability ARX-related", "description": "A non-syndromic X-linked intellectual disability characterized by moderate to profound intellectual disability with variable additional features that has_material_basis_in hemizygous mutation in ARX on chromosome Xp21.3." }, "synonyms": [ { "id": "DOID:0112021", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0112021", "name": "ARX-related intellectual disability", "description": "" }, { "id": "DOID:0112021", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0112021", "name": "MRXARX", "description": "" }, { "id": "DOID:0112021", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0112021", "name": "X-linked mental retardation 29", "description": "" }, { "id": "DOID:0112021", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0112021", "name": "X-linked mental retardation 29 and others", "description": "" }, { "id": "DOID:0112021", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0112021", "name": "X-linked mental retardation 32", "description": "" }, { "id": "DOID:0112021", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0112021", "name": "X-linked mental retardation 33", "description": "" }, { "id": "DOID:0112021", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0112021", "name": "X-linked mental retardation 38", "description": "" }, { "id": "DOID:0112021", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0112021", "name": "X-linked mental retardation 43", "description": "" }, { "id": "DOID:0112021", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0112021", "name": "X-linked mental retardation 52", "description": "" }, { "id": "DOID:0112021", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0112021", "name": "X-linked mental retardation 54", "description": "" }, { "id": "DOID:0112021", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0112021", "name": "X-linked mental retardation 76", "description": "" }, { "id": "DOID:0112021", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0112021", "name": "X-linked mental retardation 87", "description": "" }, { "id": "DOID:0112021", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0112021", "name": "X-linked mental retardation with or without seizures ARX-related", "description": "" }, { "id": "MONDO:0010317", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010317", "name": "intellectual disability, X-linked, with or without seizures, ARX-related", "description": "" }, { "id": "MONDO:0010317", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010317", "name": "ARX-related intellectual disability", "description": "" }, { "id": "MONDO:0010317", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010317", "name": "intellectual developmental disorder, X-linked 29, X-linked recessive", "description": "" }, { "id": "MONDO:0010317", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010317", "name": "intellectual disability, X-linked, with or without seizures, ARX-related", "description": "" }, { "id": "MONDO:0010317", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010317", "name": "MRX52", "description": "" }, { "id": "MONDO:0010317", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010317", "name": "MRXARX", "description": "" }, { "id": "MONDO:0010317", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010317", "name": "intellectual disability, X-linked 52", "description": "" }, { "id": "MONDO:0010317", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010317", "name": "mental retardation, X-linked 29", "description": "" }, { "id": "MONDO:0010317", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010317", "name": "mental retardation, X-linked 32", "description": "" }, { "id": "MONDO:0010317", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010317", "name": "mental retardation, X-linked 33", "description": "" }, { "id": "MONDO:0010317", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010317", "name": "mental retardation, X-linked 38", "description": "" }, { "id": "MONDO:0010317", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010317", "name": "mental retardation, X-linked 43", "description": "" }, { "id": "MONDO:0010317", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010317", "name": "mental retardation, X-linked 52", "description": "" }, { "id": "MONDO:0010317", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010317", "name": "mental retardation, X-linked 54", "description": "" }, { "id": "MONDO:0010317", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010317", "name": "mental retardation, X-linked 76", "description": "" }, { "id": "MONDO:0010317", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010317", "name": "mental retardation, X-linked 87", "description": "" }, { "id": "MONDO:0010317", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010317", "name": "mental retardation, X-linked, with or without seizures, ARX-RELATED", "description": "" }, { "id": "MONDO:0010317", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010317", "name": "mental retardation, X-linked, with or without seizures, ARX-related", "description": "" }, { "id": "MIM:300419", "resource": "MIM", "url": "https://www.omim.org/entry/300419", "name": "Intellectual developmental disorder, X-linked 29", "description": "Intellectual developmental disorder, X-linked 29" } ], "unlinked_id_list": [], "evidence": [ { "id": "0112021", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112021" } ] }, { "disease_id": "DOID:0112151", "recommended_name": { "id": "DOID:0112151", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0112151", "name": "corpus callosum agenesis-abnormal genitalia syndrome", "description": "A syndrome characterized by agenesis of the corpus callosum, severe intellectual disability, seizures, and spasticity with males showing a severe phenotype and females showing a mild or non-affected phenotype that has_material_basis_in mutation in ARX on chromosome Xp21.3." }, "synonyms": [ { "id": "DOID:0112151", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0112151", "name": "Proud-Levine-Carpenter syndrome", "description": "" }, { "id": "DOID:0112151", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0112151", "name": "ACC with abnormal genitalia", "description": "" }, { "id": "DOID:0112151", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0112151", "name": "microcephaly-corpus callosum agenesis-abnormal genitalia syndrome", "description": "" }, { "id": "DOID:0112151", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0112151", "name": "corpus callosum agenesis with abnormal genitalia", "description": "" }, { "id": "DOID:0112151", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0112151", "name": "Proud syndrome", "description": "" }, { "id": "MONDO:0010224", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010224", "name": "corpus callosum agenesis-abnormal genitalia syndrome", "description": "Corpus callosum agenesis-abnormal genitalia syndrome is a rare, genetic developmental defect during embryogenesis syndrome characterized by agenesis of the corpus callosum, mild to severe neurological manifestations (intellectual disability, developmental delay, epilepsy, dystonia), and urogenital anomalies (hypospadias, cryptorchidism, renal dysplasia, ambiguous genitalia). Additionally, skeletal anomalies (limb contractures, scoliosis), dysmorphic facial features (large eyes, prominent supraorbital ridges, synophris) and optic atrophy have been observed." }, { "id": "MONDO:0010224", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010224", "name": "ACC-abnormal genitalia syndrome", "description": "" }, { "id": "MONDO:0010224", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010224", "name": "Proud syndrome", "description": "" }, { "id": "MONDO:0010224", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010224", "name": "Proud-Levine-Carpenter syndrome", "description": "" }, { "id": "MONDO:0010224", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010224", "name": "microcephaly-corpus callosum agenesis-abnormal genitalia syndrome", "description": "" }, { "id": "MONDO:0010224", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010224", "name": "New X-linked syndrome with seizures, acquired micrencephaly, and agenesis of the corpus callosum", "description": "" }, { "id": "MONDO:0010224", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010224", "name": "Proud Levine Carpenter syndrome", "description": "" }, { "id": "MIM:300004", "resource": "MIM", "url": "https://www.omim.org/entry/300004", "name": "Agenesis of the corpus callosum, with abnormal genitalia", "description": "Agenesis of the corpus callosum, with abnormal genitalia" } ], "unlinked_id_list": [], "evidence": [ { "id": "0112151", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112151" } ] }, { "disease_id": "DOID:0112238", "recommended_name": { "id": "DOID:0112238", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0112238", "name": "X-linked lissencephaly 2", "description": "A lissencephaly characterized by structural brain anomalies, early-onset intractable seizures, severe psychomotor retardation, and ambiguous genitalia that has_material_basis_in mutation in ARX on chromosome Xp21.3." }, "synonyms": [ { "id": "DOID:0112238", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0112238", "name": "X-linked lissencephaly with abnormal genitalia", "description": "" }, { "id": "DOID:0112238", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0112238", "name": "X-linked lissencephaly with ambiguous genitalia", "description": "" }, { "id": "DOID:0112238", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0112238", "name": "XLAG", "description": "" }, { "id": "DOID:0112238", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0112238", "name": "XLIS2", "description": "" }, { "id": "DOID:0112238", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0112238", "name": "XLAG (X-linked lissencephaly with abnormal genitalia) syndrome", "description": "" }, { "id": "DOID:0112238", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0112238", "name": "X-linked lissencephaly-corpus callosum agenesis-genital anomalies syndrome", "description": "" }, { "id": "MONDO:0010268", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010268", "name": "X-linked lissencephaly with abnormal genitalia", "description": "X-linked lissencephaly with abnormal genitalia (XLAG) is a severe neurological disorder that only manifests in genotypic males and includes lissencephaly with posterior-to-anterior gradient and only moderate increase in thickness of the cortex, absent corpus callosum, neonatal-onset severe epilepsy, hypothalamic dysfunction including defective temperature regulation, and ambiguous genitalia with micropenis and cryptorchidism. XLAG differs considerably from classical lissencephaly, as the resulting cortical thickness is only 6-7 mm in XLAG, rather than 15-20 mm seen in classical lissencephaly due to mutations of the PAFAH1B1 or DCX genes. In 2002, mutations in the X-linked aristaless-related homeobox gene (ARX ; Xp21.3) were identified in individuals with XLAG and in some of their female relatives. Mouse Arx and human ARX are highly expressed in both dorsal and ventral telencephalon, including the neocortical ventricular zone and germinal zone of the ganglionic eminence, with less intense signals in the subventricular zone, cortical plate, hippocampus, basal ganglia and ventral thalamus. Arx-deficient mice showed deficient tangential migration and abnormal differentiation of GABAergic interneurons in the ganglionic eminence and neocortex, as well as abnormal testicular differentiation. These characteristics include some of the clinical features of XLAG in humans. The ARX mutations in XLAG patients were predominantly premature termination mutations (large deletions, frameshift, nonsense mutations, splice site mutations) while the missense mutations were less common and located essentially in the homeobox domain. Patients carrying nonconservative missense mutations within the homeobox, showed less severe XLAG, while conservative substitution in the homeodomain caused Proud syndrome (ACC with abnormal genitalia). A non conservative missense mutation near the C-terminal aristaless domain caused unusually severe XLAG with microcephaly and mild cerebellar hypoplasia. The ARX mutations are also associated with a spectrum of milder phenotypes, without macroscopic malformations of the brain, such as X-linked infantile spasms, a syndrome featuring mental retardation associated with distal dystonic movements (Partington syndrome), autistic features and nonsyndromicintellectual deficit." }, { "id": "MONDO:0010268", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010268", "name": "X-linked lissencephaly with abnormal genitalia", "description": "" }, { "id": "MONDO:0010268", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010268", "name": "X-linked lissencephaly with ambiguous genitalia", "description": "" }, { "id": "MONDO:0010268", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010268", "name": "X-linked lissencephaly-agenesis of the corpus callosum-genital anomalies syndrome", "description": "" }, { "id": "MONDO:0010268", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010268", "name": "X-linked lissencephaly-corpus callosum agenesis-genital anomalies syndrome", "description": "" }, { "id": "MONDO:0010268", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010268", "name": "XLAG (X-linked lissencephaly with abnormal genitalia) syndrome", "description": "" }, { "id": "MONDO:0010268", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010268", "name": "lissencephaly, X-linked, type 2", "description": "" }, { "id": "MONDO:0010268", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010268", "name": "LISX2", "description": "" }, { "id": "MONDO:0010268", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010268", "name": "X-linked lissencephaly - agenesis of the corpus callosum - genital anomalies", "description": "" }, { "id": "MONDO:0010268", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010268", "name": "XLAG syndrome", "description": "" }, { "id": "MONDO:0010268", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010268", "name": "hydranencephaly with abnormal genitalia", "description": "" }, { "id": "MONDO:0010268", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010268", "name": "lissencephaly, X-linked 2", "description": "" }, { "id": "MONDO:0010268", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010268", "name": "lissencephaly, X-linked, 2", "description": "" }, { "id": "MIM:300215", "resource": "MIM", "url": "https://www.omim.org/entry/300215", "name": "Lissencephaly, X-linked 2", "description": "Lissencephaly, X-linked 2" } ], "unlinked_id_list": [], "evidence": [ { "id": "0112238", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112238" } ] }, { "disease_id": "DOID:1324", "recommended_name": { "id": "DOID:1324", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung." }, "synonyms": [ { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer", "description": "A malignant neoplasm involving the lung." }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "adenocarcinoma of lung, response to tyrosine kinase inhibitor in, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "adenocarcinoma of lung, somatic", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "cancer of lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer, protection against, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer, resistance to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer, somatic", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant lung neoplasm", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant lung tumor", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant lung tumour", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant neoplasm of lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant neoplasm of the lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant tumor of lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant tumor of the lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant tumour of lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant tumour of the lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "nonsmall cell lung cancer, response to tyrosine kinase inhibitor in, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "nonsmall cell lung cancer, somatic", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "nonsmall cell lung cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0012159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012159", "name": "lung cancer susceptibility 1", "description": "" }, { "id": "MONDO:0012159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012159", "name": "LNCR1", "description": "" }, { "id": "MONDO:0012159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012159", "name": "lung cancer susceptibility", "description": "" }, { "id": "MONDO:0012159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012159", "name": "lung cancer susceptibility 1", "description": "" }, { "id": "MONDO:0012942", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012942", "name": "lung cancer susceptibility 3", "description": "" }, { "id": "MONDO:0012942", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012942", "name": "LNCR3", "description": "" }, { "id": "MONDO:0012942", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012942", "name": "lung cancer susceptibility 3", "description": "" }, { "id": "MONDO:0012955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012955", "name": "lung cancer susceptibility 4", "description": "" }, { "id": "MONDO:0012955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012955", "name": "LNCR4", "description": "" }, { "id": "MONDO:0012955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012955", "name": "lung cancer susceptibility 4", "description": "" }, { "id": "MONDO:0013631", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013631", "name": "lung cancer susceptibility 5", "description": "" }, { "id": "MONDO:0013631", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013631", "name": "LNCR5", "description": "" }, { "id": "MONDO:0013631", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013631", "name": "lung cancer susceptibility 5", "description": "" }, { "id": "MIM:211980", "resource": "MIM", "url": "https://www.omim.org/entry/211980", "name": "Lung cancer", "description": "Lung cancer" } ], "unlinked_id_list": [ "DOID:4765" ], "evidence": [ { "id": "1324", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1324" } ] }, { "disease_id": "DOID:14744", "recommended_name": { "id": "DOID:14744", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14744", "name": "Partington syndrome", "description": "A syndrome characterized by intellectual disability, focal dystonia of the hands and dysarthria." }, "synonyms": [ { "id": "DOID:14744", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14744", "name": "X-linked Russell-Silver syndrome", "description": "" }, { "id": "MONDO:0010654", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010654", "name": "Partington syndrome", "description": "A rare neurological condition that is primarily characterized by mild to moderate intellectual disability and dystonia of the hands. Other signs and symptoms may include dysarthria, behavioral abnormalities, recurrent seizures and/or an unusual gait (style of walking). Partington syndrome usually occurs in males; when it occurs in females, the signs and symptoms are often less severe. It is caused by changes (mutations) in the ARX gene and is inherited in an X-linked recessive manner. Treatment is based on the signs and symptoms present in each person." }, { "id": "MONDO:0010654", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010654", "name": "Partington syndrome", "description": "" }, { "id": "MONDO:0010654", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010654", "name": "Partington syndrome, X-linked recessive", "description": "" }, { "id": "MONDO:0010654", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010654", "name": "Partington-Mulley syndrome", "description": "" }, { "id": "MONDO:0010654", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010654", "name": "X-linked intellectual disability-dystonia-dysarthria syndrome", "description": "" }, { "id": "MONDO:0010654", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010654", "name": "MRXS1", "description": "" }, { "id": "MONDO:0010654", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010654", "name": "PRTS", "description": "" }, { "id": "MONDO:0010654", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010654", "name": "Partington X-linked intellectual disability syndrome", "description": "" }, { "id": "MONDO:0010654", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010654", "name": "Partington X-linked mental retardation syndrome", "description": "" }, { "id": "MONDO:0010654", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010654", "name": "intellectual disability, X-linked, syndromic 1", "description": "" }, { "id": "MONDO:0010654", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010654", "name": "intellectual disability, X-linked, with dystonic movements, ataxia, and seizures", "description": "" }, { "id": "MONDO:0010654", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010654", "name": "intellectual disability-dystonic movements-ataxia-seizures syndrome", "description": "" }, { "id": "MONDO:0010654", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010654", "name": "mental retardation, X-linked 36", "description": "" }, { "id": "MONDO:0010654", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010654", "name": "mental retardation, X-linked, syndromic 1", "description": "" }, { "id": "MONDO:0010654", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010654", "name": "mental retardation, X-linked, with dystonic movements, ataxia, and seizures", "description": "" }, { "id": "MIM:309510", "resource": "MIM", "url": "https://www.omim.org/entry/309510", "name": "Partington syndrome", "description": "Partington syndrome" } ], "unlinked_id_list": [], "evidence": [ { "id": "14744", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14744" } ] }, { "disease_id": "DOID:2340", "recommended_name": { "id": "DOID:2340", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2340", "name": "craniosynostosis", "description": "A synostosis that results_in premature fusion located_in skull." }, "synonyms": [ { "id": "DOID:2340", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2340", "name": "Premature closure of cranial sutures", "description": "" }, { "id": "MONDO:0008426", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008426", "name": "Shprintzen-Goldberg syndrome", "description": "Shprintzen-Goldberg syndrome (SGS) is a very rare genetic disorder characterized by craniosynostosis, craniofacial and skeletal abnormalities, marfanoid habitus, cardiac anomalies, neurological abnormalities, and intellectual disability." }, { "id": "MONDO:0008426", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008426", "name": "Marfanoid craniosynostosis syndrome", "description": "" }, { "id": "MONDO:0008426", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008426", "name": "SGS", "description": "" }, { "id": "MONDO:0008426", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008426", "name": "Shprintzen Goldberg Syndrome", "description": "" }, { "id": "MONDO:0008426", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008426", "name": "Shprintzen-Goldberg syndrome", "description": "" }, { "id": "MONDO:0008426", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008426", "name": "Marfanoid disorder with craniosynostosis type 1", "description": "" }, { "id": "MONDO:0008426", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008426", "name": "Marfanoid-craniosynostosis syndrome", "description": "" }, { "id": "MONDO:0008426", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008426", "name": "Shprintzen-Goldberg craniosynostosis syndrome", "description": "" }, { "id": "MONDO:0008426", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008426", "name": "Shprintzen-Goldberg marfanoid syndrome", "description": "" }, { "id": "MONDO:0010903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010903", "name": "craniosynostosis, Adelaide type", "description": "" }, { "id": "MONDO:0010903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010903", "name": "craniosynostosis, Adelaide type", "description": "" }, { "id": "MONDO:0010903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010903", "name": "CRSA", "description": "" }, { "id": "MIM:182212", "resource": "MIM", "url": "https://www.omim.org/entry/182212", "name": "Shprintzen-Goldberg craniosynostosis syndrome", "description": "Shprintzen-Goldberg craniosynostosis syndrome" } ], "unlinked_id_list": [], "evidence": [ { "id": "2340", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2340" } ] }, { "disease_id": "DOID:3717", "recommended_name": { "id": "DOID:3717", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3717", "name": "gastric adenocarcinoma", "description": "A stomach carcinoma that derives_from epithelial cells of glandular origin." }, "synonyms": [ { "id": "DOID:3717", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3717", "name": "adenocarcinoma of stomach", "description": "" }, { "id": "DOID:3717", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3717", "name": "stomach adenocarcinoma", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "3717", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3717" } ] }, { "disease_id": "DOID:3910", "recommended_name": { "id": "DOID:3910", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3910", "name": "lung adenocarcinoma", "description": "A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin." }, "synonyms": [ { "id": "DOID:3910", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3910", "name": "bronchogenic lung adenocarcinoma", "description": "" }, { "id": "DOID:3910", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3910", "name": "nonsmall cell adenocarcinoma", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "3910", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3910" } ] }, { "disease_id": "DOID:4926", "recommended_name": { "id": "DOID:4926", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4926", "name": "bronchiolo-alveolar adenocarcinoma", "description": "A lung adenocarcinoma characterized by a predominantly lepidic pattern and 5 mm or less invasion in greatest dimension." }, "synonyms": [ { "id": "DOID:4926", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4926", "name": "Bronchioalveolar lung carcinoma", "description": "" }, { "id": "DOID:4926", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4926", "name": "Bronchioloalveolar carcinoma", "description": "" }, { "id": "DOID:4926", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4926", "name": "Minimally Invasive Lung Adenocarcinoma", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "4926", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4926" } ] }, { "disease_id": "DOID:684", "recommended_name": { "id": "DOID:684", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver." }, "synonyms": [ { "id": "DOID:684", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:684", "name": "Hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma", "description": "A malignant tumor that arises from hepatocytes. Hepatocellular carcinoma is relatively rare in the United States but very common in all African countries south of the Sahara and in Southeast Asia. Most cases are seen in patients over the age of 50 years, but this tumor can also occur in younger individuals and even in children. Hepatocellular carcinoma is more common in males than females and is associated with hepatitis B, hepatitis C, chronic alcohol abuse and cirrhosis. Serum elevation of alpha-fetoprotein occurs in a large percentage of patients with hepatocellular carcinoma. Grossly, hepatocellular carcinoma may present as a single mass, as multiple nodules, or as diffuse liver involvement. Microscopically, there is a wide range of differentiation from tumor to tumor (well differentiated to poorly differentiated tumors). Hepatocellular carcinomas quickly metastasize to regional lymph nodes and lung. The overall median survival of untreated liver cell carcinoma is about 4 months. The most effective treatment of hepatocellular carcinoma is complete resection of the tumor. Lately, an increasing number of tumors have been treated with liver transplantation." }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "HCC", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "cancer, hepatocellular", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of liver", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of the liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma, hepatocellular, malignant", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatoblastoma, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular adenocarcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular cancer", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular cancer, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma, childhood type, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver cell cancer (hepatocellular carcinoma)", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver cell carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "primary carcinoma of liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "primary carcinoma of the liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "adult hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "adult primary hepatocellular carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma", "description": "A malignant tumor that arises from hepatocytes. Hepatocellular carcinoma is relatively rare in the United States but very common in all African countries south of the Sahara and in Southeast Asia. Most cases are seen in patients over the age of 50 years, but this tumor can also occur in younger individuals and even in children. Hepatocellular carcinoma is more common in males than females and is associated with hepatitis B, hepatitis C, chronic alcohol abuse and cirrhosis. Serum elevation of alpha-fetoprotein occurs in a large percentage of patients with hepatocellular carcinoma. Grossly, hepatocellular carcinoma may present as a single mass, as multiple nodules, or as diffuse liver involvement. Microscopically, there is a wide range of differentiation from tumor to tumor (well differentiated to poorly differentiated tumors). Hepatocellular carcinomas quickly metastasize to regional lymph nodes and lung. The overall median survival of untreated liver cell carcinoma is about 4 months. The most effective treatment of hepatocellular carcinoma is complete resection of the tumor. Lately, an increasing number of tumors have been treated with liver transplantation." }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "HCC", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "cancer, hepatocellular", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of liver", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of the liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma, hepatocellular, malignant", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatoblastoma, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular adenocarcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular cancer", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular cancer, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma, childhood type, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver cell cancer (hepatocellular carcinoma)", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver cell carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "primary carcinoma of liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "primary carcinoma of the liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "adult hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "adult primary hepatocellular carcinoma", "description": "" }, { "id": "MIM:114550", "resource": "MIM", "url": "https://www.omim.org/entry/114550", "name": "Hepatocellular carcinoma", "description": "Hepatocellular carcinoma" } ], "unlinked_id_list": [], "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ] }, { "disease_id": "DOID:9256", "recommended_name": { "id": "DOID:9256", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum." }, "synonyms": [ { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer", "description": "A primary or metastatic malignant neoplasm that affects the colon or rectum. Representative examples include carcinoma, lymphoma, and sarcoma." }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "cancer of colorectum", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "cancer of large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "cancer of large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "cancer of the large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colon cancer, advanced, somatic", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colon cancer, somatic", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer with chromosomal instability, somatic", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer, somatic", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectum cancer", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant colorectal neoplasm", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant colorectal tumor", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant colorectal tumour", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant colorectum neoplasm", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large bowel neoplasm", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large bowel tumor", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large bowel tumour", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large intestine neoplasm", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large intestine tumor", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large intestine tumour", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of colorectum", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of the large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of the large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumor of large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumor of large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumor of the large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumor of the large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumour of large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumour of large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": 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"categories": [ "Protein" ] }, { "id": "Q9W2P8-1", "url": "https://www.uniprot.org/uniprotkb/Q9W2P8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMTTTTSQHHQHHPIMPPAMRPAPVQESPVSRPRAVYSIDQILGNQHQIKRSDTPSEVLITHPHHGHPHHIHHLHSSNSNGSNHLSHQQQQQHSQQQHHSQQQQQQQQLQVQAKREDSPTNTDGGLDVDNDDELSSSLNNGHDLSDMERPRKVRRSRTTFTTFQLHQLERAFEKTQYPDVFTREDLAMRLDLSEARVQVWFQNRRAKWRKREKFMNQDKAGYLLPEQGLPEFPLGIPLPPHGLPGHPGSMQSEFWPPHFALHQHFNPAAAAAAGLLPQHLMAPHYKLPNFHTLLSQYMGLSNLNGIFGAGAAAAAAAASAGYPQNLSLHAGLSAMSQVSPPCSNSSPRESPKLVPHPTPPHATPPAGGNGGGGLLTGGLISTAAQSPNSAAGASSNASTPVSVVTKGED", "length": 409, "header": "tr|Q9W2P8-1|Q9W2P8_DROME Isoform 1 of Homeobrain OS=Drosophila melanogaster OX=7227 GN=hbn PE=4 SV=3 CANONICAL=Q9W2P8-1" }, "isoforms": [ { "isoform_ac": "Q9W2P8-1", "url": "https://www.uniprot.org/uniprotkb/Q9W2P8/entry#Q9W2P8-1", "sequence": { "sequence": 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"site_lbl": "Thr358", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W2P8", "url": "https://www.uniprot.org/uniprotkb/Q9W2P8" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W2P8", "url": "https://www.uniprot.org/uniprotkb/Q9W2P8" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2P8", "url": "https://www.uniprot.org/uniprotkb/Q9W2P8" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2P8", "url": "https://www.uniprot.org/uniprotkb/Q9W2P8" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W2P8", "url": "https://www.uniprot.org/uniprotkb/Q9W2P8" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W2P8", "url": "https://www.uniprot.org/uniprotkb/Q9W2P8" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W2P8", "url": "https://www.uniprot.org/uniprotkb/Q9W2P8" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2P8", "url": "https://www.uniprot.org/uniprotkb/Q9W2P8" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2P8", "url": "https://www.uniprot.org/uniprotkb/Q9W2P8" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W2P8", "url": "https://www.uniprot.org/uniprotkb/Q9W2P8" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W2P8", "url": "https://www.uniprot.org/uniprotkb/Q9W2P8" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG33152", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG33152", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2KXF6-1", "protein_name": "Aristaless-related homeobox protein", "gene_name": "arxb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSSEVEEDNPEQTNCRCKTPTLLSSYCIDSILGRKSPLKVQETPHSLWPLHPHMHLPPKLRRPFAPLTDSSTDETAGPRLLQTACEKLKITEASIVNISRAGSYQEHASCKNTPINEEEGADICGETNVTLKQEREAFLKNSEETSLSAGSDTEDGMLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKREKVGVQPHTLSLHYSGAPPAAQSLCHYLSGNPFVPNPHPAIDSAWPAPFQRLAQPAQNSVSPPGFSALLGAAMFRHPAFFNPTFGRLFTSLGPMALQRIPLPAIEGPIQRSHLTTSLLSSSPPLPSSPTVDLRASSIAALRLKAKEHSAQLTHITAAGTAGKEEC", "length": 385 }, "evidence": [ { "id": "HGNC:18060", "url": "https://alliancegenome.org/gene/HGNC:18060#orthology", "database": "AGR" }, { "id": "MGI:1097716", "url": "https://alliancegenome.org/gene/MGI:1097716#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PL59-1", "protein_name": "Homeobox protein aristaless-like 3 isoform X1", "gene_name": "alx3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "METESSLSFSSPPNRITPDNSPGLEHNSSSFFQCDDLQKSPHLALAHRHEFFMGRYADGGSADFTHGVSSTTPRASPGKHTKYLENINQDQKPSITEKNSSFYETNSDAGDKTLSKPLGYPALDSECCGKLKEASNGLTGDSIADSIDLSGKNKKRRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTELTEARVQVWFQNRRAKWRKRERYGKMQEVRNHFAATYDISLLPRSDTYQMQNSLWPSGAGATGAGGASSACVLGTENMPSSCMSPYPHPHGNLPGLMGMSASPGHHHHHHHHHHHPSHHPSINGIYSLHGFPGSLGAHTFEAGPESEYKPSGLVALRMKTKDPGSLLSWPT", "length": 364 }, "evidence": [ { "id": "HGNC:449", "url": "https://alliancegenome.org/gene/HGNC:449#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120221-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120221-3#orthology", "database": "AGR" }, { "id": "MGI:1277097", "url": "https://alliancegenome.org/gene/MGI:1277097#orthology", "database": "AGR" }, { "id": "RGD:1359270", "url": "https://alliancegenome.org/gene/RGD:1359270#orthology", "database": "AGR" }, { "id": "FB:FBgn0008636", "url": "https://alliancegenome.org/gene/FB:FBgn0008636#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABZ3NND2-1", "protein_name": "Rhox homeobox family member 2B", "gene_name": "Rhoxf2b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVLPDGEGRNEEDSRQGQPGSEATAVGGDEAEELSGQGGRPVRTAGLMDNQEDNGATGCDQENEKQPKEPVLKDMGTTEDVQSAPELVTRMHPMPLRVCRVEPISVRVPRVQRIQRMVPQTACATYGASWTAYSTYGALYTGYVTYSALCTAYATYGASCAAYATYGALWTPSATYGVPCTAYAIYGALCTTYATYSASCTTYATYGAPWTAYATYGAPWTAYVPDSAPWTAYATYGACTAYATYGAPYTAYVTYDTAWTASSMYGALWTAYATYGDLCTGYATYGALCTIYAPSGALCTAHSAYGSLYTTYATYGAPCTAYATCGAPWTVYVTYTALCKAYVMYGAPCTSYAIYGALCTAFTPYGAFCTAYATYGVLWTAFDTCDALFTAYATYNAPSSNVQPEPVLVPRRHLHDRFTDPELQELERVFQRNHYLSAEERKQLARGMGVSEAKLQRWFKKRREHFRREQSQSGGAPPGNTPPLSEDGAGALVYHP", "length": 496 }, "evidence": [ { "id": "HGNC:33519", "url": "https://alliancegenome.org/gene/HGNC:33519#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AC58HT46-1", "protein_name": "Homeobox protein aristaless-like 4", "gene_name": "alx4b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNADTCVSYCDMTSMDSYYSPAAPGQGRVQQANPYRTFQSSDSKYSPTFLPAKGQTYGEKPRSPFHQDCPTLDDSTAEGAYSKYHLFMQRPACKSPSEDSKLEDGALISCYGKDGTGLTDTDMPQSADPTALDGSFISVKDAGLKGQSDRPVSDIGSALDKSEAESNKGKKRRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAKWRKRERFGQMQQVRTHFSTAYELPLLTRPENYAQIQNPSWLSGSSSASPVPGCVVPCDTVSSCMTPHPHSASGVSDFLGMPSPGGSMAQTHMGSLFGSSGVGGTINGFDLSVEPDRKSSSIASLRMKAKEHSAAITWAT", "length": 364 }, "evidence": [ { "id": "HGNC:450", "url": "https://alliancegenome.org/gene/HGNC:450#orthology", "database": "AGR" }, { "id": "MGI:108359", "url": "https://alliancegenome.org/gene/MGI:108359#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A2AWM0-1", "protein_name": "Reproductive homeobox 3C", "gene_name": "Rhox3c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSISNWIHSNVERAGRNLFQVNGHRSALLPELPQDYHRASRSVYGCETKMDSTQGTKVLPAEEARNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEAPRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREQYRWYKRL", "length": 215 }, "evidence": [ { "id": "HGNC:33519", "url": "https://alliancegenome.org/gene/HGNC:33519#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A6YP92-1", "protein_name": "Homeobox protein ARX", "gene_name": "Arx", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSNQYQEEGCSERPECKSKSPTLLSSYCIDSILGRRSPCKMRLLGAAQSLPAPLASRTDQEKAMQGSPKGSSAPFEAELHLPPKLRRLYGPGGGRLLQGAAAAAAAAAAAAAAAATATGTAGPRGEVPPPPPPAARPGERQDSAGAVAAAAAAAWDTLKISQAPQVSISRSKSYRENGAPFVPPPPALDELGGPGGVAHPEERLSAASGPGSAPAAGGGTGTEEDEEELLEDEEDEDEEEELLEDDEEELLEDDARALLKEPRRCSVATTGTVAAAAAAAAAAAAVATEGGELSPKEELLLHPEDAEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKREKAGAQTHPPGLPFPGPLSATHPLSPYLDASPFPPHHPALDSAWTAAAAAAAAAFPSLPPPPGSASLPPSGAPLGLSTFLGAAVFRHPAFISPAFGRLFSTMAPLTSASTAAALLRQPTPAVEGAVASGALADPATAAADRRASSIAALRLKAKEHAAQLTQLNILPGTSTGKEVC", "length": 566 }, "evidence": [ { "id": "HGNC:18060", "url": "https://alliancegenome.org/gene/HGNC:18060#orthology", "database": "AGR" }, { "id": "RGD:1562672", "url": "https://alliancegenome.org/gene/RGD:1562672#orthology", "database": "AGR" }, { "id": "MGI:1097716", "url": "https://alliancegenome.org/gene/MGI:1097716#orthology", "database": "AGR" }, { "id": "FB:FBgn0008636", "url": "https://alliancegenome.org/gene/FB:FBgn0008636#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZEM1-1", "protein_name": "Homeobox protein aristaless-like 4", "gene_name": "Alx4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNAETCVSYCESPATAMDAYYSPVSQSREGSSPFRGFPGGDKFGTTFLSAAAKGQGFGDAKGRARYGAGQQDLAAPLESNAGARGSFNKFQPQPPTPQPPPAPPAPPAHLYLQRGACKTPPDGSLKLQEGSGGHNAALQVPCYAKESNLGEPELPPDSEPVGMDNSYLSVKETGAKGPQDRAGAEIPSPLEKTDSESSKGKKRRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWFQNRRAKWRKRERFGQMQQVRTHFSTAYELPLLTRAENYAQIQNPSWIGNNGAASPVPACVVPCDPVPACMSPHAHPPGSGASSVSDFLSVSGAGSHVGQTHMGSLFGAAGISPGLNGYEMNGEPDRKTSSIAALRMKAKEHSAAISWAT", "length": 399 }, "evidence": [ { "id": "HGNC:450", "url": "https://alliancegenome.org/gene/HGNC:450#orthology", "database": "AGR" }, { "id": "MGI:108359", "url": "https://alliancegenome.org/gene/MGI:108359#orthology", "database": "AGR" }, { "id": "RGD:1310201", "url": "https://alliancegenome.org/gene/RGD:1310201#orthology", "database": "AGR" }, { "id": "FB:FBgn0008636", "url": "https://alliancegenome.org/gene/FB:FBgn0008636#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7FGP3-1", "protein_name": "Homeobox protein aristaless-like 4", "gene_name": "alx4a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNAETCVSYCEMTSMDSYYSPSAPQGRDHQANPFRTFQASDTKYSPAFLTNKGQGYGEKSGSPFQQECQSLDATAGEGTFNKYHLFMQRSSCKTPPDSSKLQQENSGHNGGLIACYGKDSTGLTDSELPQNSDPAGMDGSYLSVKDSGVKSPQQATSELASPLDKTEGESNKGKKRRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAKWRKRERFGQMQQVRTHFSTAYELPLLTRPENYAQIQNPSWIGGSSAASPVPGCVVPCDSVTSCMPPHPHAASGVSDFLGVPSPGSHMGQTHMGSLFGSPGMGTGINGYDLNMDPDRKSSSIAALRMKAKEHSAAISWAT", "length": 368 }, "evidence": [ { "id": "HGNC:450", "url": "https://alliancegenome.org/gene/HGNC:450#orthology", "database": "AGR" }, { "id": "MGI:108359", "url": "https://alliancegenome.org/gene/MGI:108359#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1LN97-1", "protein_name": "ALX homeobox 3", "gene_name": "Alx3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDPERCAPFAVGPAAGPYAAARDEAPGPQGTPDAAPHLRPAPPRGPRLSRFPACGPLEPYLPEPAKPPAKYLQDLGPGPVLNGGHFYKGSSEAEEKASKAASFPQLPVDCRGGPRDGPSNVQGSPGPCLASLSVPLSPGLPDSMELAKSKSKKRRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAKWRKRERYGKIQEGRNPFTTAYDISVLPRTDSHPQLQNSLWSSPGSGSPGGPCLMPPEGIPSPCMSPYSHSHGNVAGFMGVPASPAAHPGIYSIHGFPPALGGHSFEPSPDGDYKSPSLVSLRMKPKEPPSLLNWTT", "length": 343 }, "evidence": [ { "id": "HGNC:449", "url": "https://alliancegenome.org/gene/HGNC:449#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120221-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120221-3#orthology", "database": "AGR" }, { "id": "MGI:1277097", "url": "https://alliancegenome.org/gene/MGI:1277097#orthology", "database": "AGR" }, { "id": "RGD:1359270", "url": "https://alliancegenome.org/gene/RGD:1359270#orthology", "database": "AGR" }, { "id": "FB:FBgn0008636", "url": "https://alliancegenome.org/gene/FB:FBgn0008636#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M524-1", "protein_name": "Rhox homeobox family member 13", "gene_name": "Rhoxf13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQRVSFDHNYYFMECEEETNAGVQARAVASTSTMEASGAMAVAQAGAACRSHASRGTIGYDTVYEPNVKGDPKQESESDTEESYDDEDDDEDEGDEDDLSTSDQDTSDPEQEEAALFVAAAAPPIAPAAAAIQIPGPHRSRRRRHRRHRRSSPYLFTQWQVEEMENLFEETPYPDVLTRGELARTLNVPEVKVKVWFSNRRAKQRKNERRAMLRNMPSGAEDFIFMTDVEEPC", "length": 234 }, "evidence": [ { "id": "HGNC:29993", "url": "https://alliancegenome.org/gene/HGNC:29993#orthology", "database": "AGR" }, { "id": "MGI:1920864", "url": "https://alliancegenome.org/gene/MGI:1920864#orthology", "database": "AGR" }, { "id": "RGD:1586264", "url": "https://alliancegenome.org/gene/RGD:1586264#orthology", "database": "AGR" }, { "id": "FB:FBgn0008636", "url": "https://alliancegenome.org/gene/FB:FBgn0008636#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F6YCR7-1", "protein_name": "Homeobox protein Rhox13", "gene_name": "Rhox13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAHGVPFDHNYYIVECKEETNAEAQAGAMAATSTEEAPGAVEVAQAAVASSHDSGGAIGCATVKESESDSESESDSESESDSSDSSDESDDDSSTSDEDTSDPEEAAAPSVAAVAAAAAPPTVPAAAAIQIPGPYRYRPPRRHVRRRRRGPPFHFAQWQVEEMESLFEETQYPDLLTRGELARTLNVPEVKVKVWFTNRRAKQRKIERREMLRNIPPGAEDFIFITDFEEPS", "length": 232 }, "evidence": [ { "id": "HGNC:29993", "url": "https://alliancegenome.org/gene/HGNC:29993#orthology", "database": "AGR" }, { "id": "MGI:1920864", "url": "https://alliancegenome.org/gene/MGI:1920864#orthology", "database": "AGR" }, { "id": "RGD:1586264", "url": "https://alliancegenome.org/gene/RGD:1586264#orthology", "database": "AGR" }, { "id": "FB:FBgn0008636", "url": "https://alliancegenome.org/gene/FB:FBgn0008636#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MUB9-1", "protein_name": "Reproductive homeobox 2G", "gene_name": "Rhox2g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSINYKLDVGPEEDEENANGIKTLMVLLAGEGRNEGESGRGLPGSGVSAAEGYRAGELSAGGLAAPVADLMDNNNQEDLGATGCAQEKEKQPEEPVPDSMGDLENVKPMSGPWSTVNPVRVLVPEFLHGWQQSFNVLQLQELESIFQCNHYISTTEAKCLARSMGVSKATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "HGNC:33519", "url": "https://alliancegenome.org/gene/HGNC:33519#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0R8Z6-1", "protein_name": "Extraembryonic, spermatogenesis, homeobox 1", "gene_name": "AABR07040695.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESHKKCRCCYCTDLKNFAGAVKEETLEDPQPSLSSTLLEGANYQGNEEFETTYYSNFGDSQKEEEVEMETSLFNSMFLEETNYQEPKELEPASKEAAAPVAEAPRAWKGNENLGGGILESNAQLGEADATPMPQSLMRPLMQPVARSSLQPLPANLLQAPQQPEQQPQGQPQGQPQQQQLQQQPKPRRYRISFTQIQLQELEAYFQRVQYPDLFARMELARRLGLPESRVQVWFQNRRAKWRRLRRAQAYRNMVPVAMGPPVGVFVDDHYGPIPVVEVIWKCYPMVPRPMHPQMMPLPPRGPPIFRMPLPFRPPPPPPFPWPPVPPEIHMPNAAMGFNPNPNPNPNPNPNPNPNPNPNPNPNPNGNVNSAGPRY", "length": 375 }, "evidence": [ { "id": "HGNC:14865", "url": "https://alliancegenome.org/gene/HGNC:14865#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O35085-1", "protein_name": "Homeobox protein ARX", "gene_name": "Arx", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNQYQEEGCSERPECKSKSPTLLSSYCIDSILGRRSPCKMRLLGAAQSLPAPLASRADQEKAMQGSPKSSSAPFEAELHLPPKLRRLYGPGGGRLLQGAAAAAAAAAAAAAAATATGTAGPRGEVPPPPPPAARPGERQDSAGAVAAAAAAAAWDTLKISQAPQVSISRSKSYRENGAPFVPPPPALDELSGPGGVAHPEERLSAASGPGSAPAAGGGTGAEDDEEELLEDEEDEEEEEELLEDDDEELLEDDARALLKEPRRCSVATTGTVAAAAAAAAAAVATEGGELSPKEELLLHPEDAEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKREKAGAQTHPPGLPFPGPLSATHPLSPYLDASPFPPHHPALDSAWTAAAAAAAAAFPSLPPPPGSASLPPSGAPLGLSTFLGAAVFRHPAFISPAFGRLFSTMAPLTSASTAAALLRQPTPAVEGAVASGALADPATAAADRRASSIAALRLKAKEHAAQLTQLNILPGTSTGKEVC", "length": 564 }, "evidence": [ { "id": "HGNC:18060", "url": "https://alliancegenome.org/gene/HGNC:18060#orthology", "database": "AGR" }, { "id": "RGD:1562672", "url": "https://alliancegenome.org/gene/RGD:1562672#orthology", "database": "AGR" }, { "id": "MGI:1097716", "url": "https://alliancegenome.org/gene/MGI:1097716#orthology", "database": "AGR" }, { "id": "FB:FBgn0008636", "url": "https://alliancegenome.org/gene/FB:FBgn0008636#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O35137-1", "protein_name": "Homeobox protein aristaless-like 4", "gene_name": "Alx4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNAETCVSYCESPAAAMDAYYSPVSQSREGSSPFRGFPGGDKFGTTFLSAGAKGQGFGDAKSRARYGAGQQDLAAPLESSSGARGSFNKFQPQPPTPQPPPAPPAPPAHLYLQRGACKTPPDGSLKLQEGSGGHNAALQVPCYAKESNLGEPELPPDSEPVGMDNSYLSVKETGAKGPQDRASAEIPSPLEKTDSESNKGKKRRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWFQNRRAKWRKRERFGQMQQVRTHFSTAYELPLLTRAENYAQIQNPSWIGNNGAASPVPACVVPCDPVPACMSPHAHPPGSGASSVSDFLSVSGAGSHVGQTHMGSLFGAAGISPGLNGYEMNGEPDRKTSSIAALRMKAKEHSAAISWAT", "length": 399 }, "evidence": [ { "id": "HGNC:450", "url": "https://alliancegenome.org/gene/HGNC:450#orthology", "database": "AGR" }, { "id": "MGI:108359", "url": "https://alliancegenome.org/gene/MGI:108359#orthology", "database": "AGR" }, { "id": "RGD:1310201", "url": "https://alliancegenome.org/gene/RGD:1310201#orthology", "database": "AGR" }, { "id": "FB:FBgn0008636", "url": "https://alliancegenome.org/gene/FB:FBgn0008636#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O42115-1", "protein_name": "Aristaless-related homeobox protein A", "gene_name": "arxa", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSSQYDDDSRDRSECKSKSPTVLSSYCIDSILGRRSPCKVRQLGAQSLPAPVRPDHEMTTEVTSKENSFDSDMHLPPKLRRLYGPGGKYLDSGRGFHEHLEKGERERLLDQACESLKISQAPQVSISRSKSYRENAPFSQSDEGQSPEHMAQELVELSTLKFEEDVVKEEACGDNSLSPKDEESLHNDGDVKDGEDSVCLSAGSDSEEGMLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKREKAGVQAHPTGLPFPGPLAAAHPLSHYLEGGPFPPHPHPALESAWTAAAAAAAAFPGLAPPPNSSALPPATPLGLGTFLGTAMFRHPAFIGPTFGRLFSSMGPLTSASTAAALLRQTAPPVESPVQPSAALPEPPSSSSSTAADRRASSIAALRLKAKEHSAQLTQLNILPSGTAGKEVC", "length": 453 }, "evidence": [ { "id": "HGNC:18060", "url": "https://alliancegenome.org/gene/HGNC:18060#orthology", "database": "AGR" }, { "id": "RGD:1562672", "url": "https://alliancegenome.org/gene/RGD:1562672#orthology", "database": "AGR" }, { "id": "MGI:1097716", "url": "https://alliancegenome.org/gene/MGI:1097716#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O70137-1", "protein_name": "Homeobox protein aristaless-like 3", "gene_name": "Alx3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPERCAPFSVGPAAGPYAAAGDEAPGPQGTPDAAPHLHPAPPRGPRLSRFPACGPLEPYLPEPAKPPAKYLQDLGPGPVLNGGHFYEGSAEAEEKASKAASFPQLPVDCRGGPRDGPSNVQASPGPCLASLSVPLSPGLPDSMELAKTKSKKRRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAKWRKRERYGKMQEGRNPFTTAYDISVLPRTDSHPQLQNSLWPSPGSGSPGGPCLMSPEGIPSPCMSPYSHSHGNVAGFMGVPASPAAHPGIYSIHGFPPALGGHSFEPSPDGDYKSPSLVSLRMKPKEPPGLLNWTT", "length": 343 }, "evidence": [ { "id": "HGNC:449", "url": "https://alliancegenome.org/gene/HGNC:449#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120221-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120221-3#orthology", "database": "AGR" }, { "id": "MGI:1277097", "url": "https://alliancegenome.org/gene/MGI:1277097#orthology", "database": "AGR" }, { "id": "RGD:1359270", "url": "https://alliancegenome.org/gene/RGD:1359270#orthology", "database": "AGR" }, { "id": "FB:FBgn0008636", "url": "https://alliancegenome.org/gene/FB:FBgn0008636#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O95076-1", "protein_name": "Homeobox protein aristaless-like 3", "gene_name": "ALX3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPEHCAPFRVGPAPGPYVASGDEPPGPQGTPAAAPHLHPAPPRGPRLTRFPACGPLEPYLPEPAKPPAKYLQDLGPGPALNGGHFYEGPAEAEEKTSKAASFPQLPLDCRGGPRDGPSNLQGSPGPCLASLHLPLSPGLPDSMELAKNKSKKRRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAKWRKRERYGKIQEGRNPFTAAYDISVLPRTDSHPQLQNSLWASPGSGSPGGPCLVSPEGIPSPCMSPYSHPHGSVAGFMGVPAPSAAHPGIYSIHGFPPTLGGHSFEPSSDGDYKSPSLVSLRVKPKEPPGLLNWTT", "length": 343 }, "evidence": [ { "id": "HGNC:449", "url": "https://alliancegenome.org/gene/HGNC:449#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120221-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120221-3#orthology", "database": "AGR" }, { "id": "MGI:1277097", "url": "https://alliancegenome.org/gene/MGI:1277097#orthology", "database": "AGR" }, { "id": "RGD:1359270", "url": "https://alliancegenome.org/gene/RGD:1359270#orthology", "database": "AGR" }, { "id": "FB:FBgn0008636", "url": "https://alliancegenome.org/gene/FB:FBgn0008636#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0C7M4-1", "protein_name": "Rhox homeobox family member 2B", "gene_name": "RHOXF2B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPPDQCSQYMTSLLSPAVDDEKELQDMNAMVLSLTEEVKEEEEDAQPEPEQGTAAGEKLKSAGAQGGEEKDGGGEEKDGGGAGVPGHLWEGNLEGTSGSDGNVEDSDQSEKEPGQQYSRPQGAVGGLEPGNAQQPNVHAFTPLQLQELECIFQREQFPSEFLRRRLARSMNVTELAVQIWFENRRAKWRRHQRALMARNMLPFMAVGQPVMVTAAEAITAPLFISGMRDDYFWDHSHSSSLCFPMPPFPPPSLPLPLMLLPPMPPAGQAEFGPFPFVIVPSFTFPNV", "length": 288 }, "evidence": [ { "id": "HGNC:33519", "url": "https://alliancegenome.org/gene/HGNC:33519#orthology", "database": "AGR" }, { "id": "FB:FBgn0008636", "url": "https://alliancegenome.org/gene/FB:FBgn0008636#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P70368-1", "protein_name": "Homeobox protein SEBOX", "gene_name": "Sebox", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASPVEASPGCASGLGPHRRKRTTFSVGQLVELERVFAARPYPDISTREHLAQVTHLPEAKIQVWFQNRRAKRIKDRKPGALNSRLELPPNSCSLPDTPQLPWDPGTSSHPLHPTSSAQYTSACPPQTSCLGPILGPGQSWSGAKVAAPWGTSGASGIHSSLEQIVPQTSLGNLSDLIYTSAIVTNVDHF", "length": 190 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-021206-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-021206-4#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q04116-1", "protein_name": "Homeobox protein YHP1", "gene_name": "YHP1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MESRNTVLPSLPNIITGTSNSPFQLHTLPNTNFPSDDQGDIRLPPLAASAHIVRPVVNIYKSPCDEERPKRKSPQAVDFLSQRVTTSMTPLSKPKKLSSHSPFTPTVRVCSKEQPPQSMHSYKKVNILTPLSAAKAVLTPTTRKEKKRSFAFITHSQETFPKKEPKIDNARLARRKRRRTSSYELGILQTAFDECPTPNKAKRIELSEQCNMSEKSVQIWFQNKRQAAKKHKNSGNTSHCKVHSNDSMSMISYSDAALEITSTPTSTKEAITAELLKTSPANTSSIFEDHHITPCKPGGQLKFHRKSVLVKRTLSNTGHSEIIKSPKGKENRLKFNAYERKPLGEVDLNSFKN", "length": 353 }, "evidence": [ { "id": "HGNC:1494", "url": "https://alliancegenome.org/gene/HGNC:1494#orthology", "database": "AGR" }, { "id": "HGNC:18060", "url": "https://alliancegenome.org/gene/HGNC:18060#orthology", "database": "AGR" }, { "id": "HGNC:449", "url": "https://alliancegenome.org/gene/HGNC:449#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-191", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-191#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120221-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120221-3#orthology", "database": "AGR" }, { "id": "RGD:1562672", "url": "https://alliancegenome.org/gene/RGD:1562672#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q06453-1", "protein_name": "Homeobox protein aristaless", "gene_name": "al", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGISEEIKLEELPQEAKLAHPDAVVLVDRAPGSSAASAGAALTVSMSVSGGAPSGASGASGGTNSPVSDGNSDCEADEYAPKRKQRRYRTTFTSFQLEELEKAFSRTHYPDVFTREELAMKIGLTEARIQVWFQNRRAKWRKQEKVGPQSHPYNPYLPGGAATMQTVVGAALPPNPFTHLGFQLRKPFDAQHAANLAAFRYPHLSAAPMIPSGYFNQFQRAPPHMLPHGMAGMYSPSSSFQSLLANMTAVPRGTPLGKPPALLVGSPDLHSPNHMLASPPTSPASGHASQHQQHPTAHPPPPQAPPQMPVGVQPAQLSPQHLVGIALTQQASSLSPTQTSPVALTLSHSPQRQLPPPSHQAPPPPPRAATPPEDRRTSSIAALRLKAREHELKLELLRQNGHGNDVVS", "length": 408 }, "evidence": [ { "id": "HGNC:18060", "url": "https://alliancegenome.org/gene/HGNC:18060#orthology", "database": "AGR" }, { "id": "RGD:1562672", "url": "https://alliancegenome.org/gene/RGD:1562672#orthology", "database": "AGR" }, { "id": "MGI:1097716", "url": "https://alliancegenome.org/gene/MGI:1097716#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q15699-1", "protein_name": "ALX homeobox protein 1", "gene_name": "ALX1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEFLSEKFALKSPPSKNSDFYMGAGGPLEHVMETLDNESFYSKASAGKCVQAFGPLPRAEHHVRLERTSPCQDSSVNYGITKVEGQPLHTELNRAMDNCNSLRMSPVKGMQEKGELDELGDKCDSNVSSSKKRRHRTTFTSLQLEELEKVFQKTHYPDVYVREQLALRTELTEARVQVWFQNRRAKWRKRERYGQIQQAKSHFAATYDISVLPRTDSYPQIQNNLWAGNASGGSVVTSCMLPRDTSSCMTPYSHSPRTDSSYTGFSNHQNQFSHVPLNNFFTDSLLTGATNGHAFETKPEFERRSSSIAVLRMKAKEHTANISWAM", "length": 326 }, "evidence": [ { "id": "HGNC:1494", "url": "https://alliancegenome.org/gene/HGNC:1494#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-191", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-191#orthology", "database": "AGR" }, { "id": "MGI:104621", "url": "https://alliancegenome.org/gene/MGI:104621#orthology", "database": "AGR" }, { "id": "RGD:2273", "url": "https://alliancegenome.org/gene/RGD:2273#orthology", "database": "AGR" }, { "id": "FB:FBgn0008636", "url": "https://alliancegenome.org/gene/FB:FBgn0008636#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q1LVQ7-1", "protein_name": "ALX homeobox protein 1", "gene_name": "alx1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEYLSDKFSLKSPAIKGSDYYMDQVMDTLDNVQYYNKASPKCVQAFPMQSNDQHSSMDRSSPCDNQSSVTYCAPKSEESSLHAMENCCSLRVSPATSGPDKTDLDELGEKCDSNVSSSKKRRHRTTFTSAQLEELEKVFQKTHYPDVYVREQLAMRTELTEARVQVWFQNRRAKWRKRERYGQIQQAKSHFAATYDISMLPRTDSYSQISNNLWTGPSAGSSVVSSCMIPRGSPPCVTSPYPHSPRAAEHGYVGFPNHQQNQFGVNHVSLNNFFADSLLASSANSHAAFETKPEFERRSSSIAVLRMKAKEHTANISWAM", "length": 320 }, "evidence": [ { "id": "HGNC:1494", "url": "https://alliancegenome.org/gene/HGNC:1494#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-191", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-191#orthology", "database": "AGR" }, { "id": "MGI:104621", "url": "https://alliancegenome.org/gene/MGI:104621#orthology", "database": "AGR" }, { "id": "RGD:2273", "url": "https://alliancegenome.org/gene/RGD:2273#orthology", "database": "AGR" }, { "id": "FB:FBgn0008636", "url": "https://alliancegenome.org/gene/FB:FBgn0008636#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q63087-1", "protein_name": "ALX homeobox protein 1", "gene_name": "Alx1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEFLSEKFALKSPPSKNSDFYMGTGGALEHVMETLDNESFYGKATAGKCVQAFGPLPRAEHHVRLDRTSPCQDSSVNYGITKVEGQPLHTELNRAMDGCNNLRMSPVKGMPEKSELDELGDKCDSNVSSSKKRRHRTTFTSLQLEELEKVFQKTHYPDVYVREQLALRTELTEARVQVWFQNRRAKWRKRERYGQIQQAKSHFAATYDISVLPRTDSYPQIQNNLWAGNTSGGSVVTSCMLPRDASSCMTPYSHSPRTDSSYTGFSNHQNQFGHVPLNNFFTDSLLTGTTNGHAFETKPEFERRSSSIAVLRMKAKEHTANISWAM", "length": 326 }, "evidence": [ { "id": "HGNC:1494", "url": "https://alliancegenome.org/gene/HGNC:1494#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-191", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-191#orthology", "database": "AGR" }, { "id": "MGI:104621", "url": "https://alliancegenome.org/gene/MGI:104621#orthology", "database": "AGR" }, { "id": "RGD:2273", "url": "https://alliancegenome.org/gene/RGD:2273#orthology", "database": "AGR" }, { "id": "FB:FBgn0008636", "url": "https://alliancegenome.org/gene/FB:FBgn0008636#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7KSE4-1", "protein_name": "Reversed polarity", "gene_name": "repo", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEHDSFDDPIFGEFGGGPLNPLGAKPLMPTTTAMHPVMLGSVHELCSQQQQQQQQQRLPDCNTILPNGGGGGAGSGGAGGSPNYVTKLDFVNKMGCYSPSQKYEYISAPQKLVEQQQQQQHHHQHHQHYTATPPPSHNGILLHKQSSQQQQQQQQQLVGILDYHPLNGKLDYSSSPKDQYEPQQLQHLYGGSPHHLDHLDHGSDGLLQDSSPVMINGGSAGGKLKKPDEMCSQLEAGGAGVTPPSSSSTVVNGTTNGTGNANSSSSAGVGIQGAAGTAGGVAAPAAKKDGSSSKKKGDPNGIKKKKTRTTFTAYQLEELERAFERAPYPDVFAREELAIKLNLSESRVQVWFQNRRAKWRKHEPPRKTGYIKTSTPPTATLNPGTLAPPFTSYPQTTTVTPPGSMDSWTSYQTPYELTPQFSLLSPAASPYGTYSGQYGAYVHESQLFPMRHYEYGSPTRMEMGATTGSVAGNGDESVANGGSYQTAELQTAQQQQLADGTLVTVHAHQQQQQQQQQLNGKYLSAEEAKYVHLQCHQSGGGLELSPGASCHLVEAQGQHYVTTATGGAASAGGTSSDDNDSGGMQTVIKSEEVSQQQQQQQGQSYVLPPFLH", "length": 612 }, "evidence": [ { "id": "HGNC:30011", "url": "https://alliancegenome.org/gene/HGNC:30011#orthology", "database": "AGR" }, { "id": "HGNC:33519", "url": "https://alliancegenome.org/gene/HGNC:33519#orthology", "database": "AGR" }, { "id": "HGNC:14865", "url": "https://alliancegenome.org/gene/HGNC:14865#orthology", "database": "AGR" }, { "id": "HGNC:29993", "url": "https://alliancegenome.org/gene/HGNC:29993#orthology", "database": "AGR" }, { "id": "MGI:1920864", "url": "https://alliancegenome.org/gene/MGI:1920864#orthology", "database": "AGR" }, { "id": "RGD:1586264", "url": "https://alliancegenome.org/gene/RGD:1586264#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8C8B0-1", "protein_name": "ALX homeobox protein 1", "gene_name": "Alx1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEFLSEKFALKSPPSKNSDFYMGTGGALEHVMETLDNESFYGKATAGKCVQAFGPLPRAEHHVRLDRTSPCQDSSVNYGITKVEGQPLHTELNRAMDNCNNLRMSPVKGMPEKSELDELGDKCDSNVSSSKKRRHRTTFTSLQLEELEKVFQKTHYPDVYVREQLALRTELTEARVQVWFQNRRAKWRKRERYGQIQQAKSHFAATYDISVLPRTDSYPQIQNNLWAGNASGGSVVTSCMLPRDASSCMTPYSHSPRTDSSYTGFSNHQNQFSHVPLNNFFTDSLLTGATNGHAFETKPEFERRSSSIAVLRMKAKEHTANISWAM", "length": 326 }, "evidence": [ { "id": "HGNC:1494", "url": "https://alliancegenome.org/gene/HGNC:1494#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-191", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-191#orthology", "database": "AGR" }, { "id": "MGI:104621", "url": "https://alliancegenome.org/gene/MGI:104621#orthology", "database": "AGR" }, { "id": "RGD:2273", "url": "https://alliancegenome.org/gene/RGD:2273#orthology", "database": "AGR" }, { "id": "FB:FBgn0008636", "url": "https://alliancegenome.org/gene/FB:FBgn0008636#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8JJ26-1", "protein_name": "Homeobox protein SEBOX", "gene_name": "sebox", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MALFYDQSFDLGLVQKINMETESDFIFNTNMLQFTDVTTKHMLSSPELDRTGHVEGQRKRKRTIFSRAQLSELERAFMITPYPDITLRERLAALTLLPESKIQVWFQNRRARSMKSKKLITPVSRRSPAKDCTFPATHPDLNLEQSPEANKSLRHHQQSLIRQALNPWPQNRPPISPDLPEILQWANRNSETPGDSSFSSCPSERIQHPFPNQSSSVWQMNCFAAHPEGLKSYCTTSQALYSSVSVDQMIPAHPSSLEEALQRQALTHYPQTSLGDISDLIYKAAVVTNLEEC", "length": 293 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-021206-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-021206-4#orthology", "database": "AGR" }, { "id": "FB:FBgn0008636", "url": "https://alliancegenome.org/gene/FB:FBgn0008636#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8N693-1", "protein_name": "Homeobox protein ESX1", "gene_name": "ESX1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESLRGYTHSDIGYRSLAVGEDIEEVNDEKLTVTSLMARGGEDEENTRSKPEYGTEAENNVGTEGSVPSDDQDREGGGGHEPEQQQEEPPLTKPEQQQEEPPLLELKQEQEEPPQTTVEGPQPAEGPQTAEGPQPPERKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRRAKWKRNQRVLMLRNTATADLAHPLDMFLGGAYYAAPALDPALCVHLVPQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMAPLPPGPPMAPLPPGPPMAPLPPRSHVPHTGLAPVHITWAPVINSYYACPFF", "length": 406 }, "evidence": [ { "id": "HGNC:14865", "url": "https://alliancegenome.org/gene/HGNC:14865#orthology", "database": "AGR" }, { "id": "FB:FBgn0008636", "url": "https://alliancegenome.org/gene/FB:FBgn0008636#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8NHV9-1", "protein_name": "Rhox homeobox family member 1", "gene_name": "RHOXF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARSLVHDTVFYCLSVYQVKISPTPQLGAASSAEGHVGQGAPGLMGNMNPEGGVNHENGMNRDGGMIPEGGGGNQEPRQQPQPPPEEPAQAAMEGPQPENMQPRTRRTKFTLLQVEELESVFRHTQYPDVPTRRELAENLGVTEDKVRVWFKNKRARCRRHQRELMLANELRADPDDCVYIVVD", "length": 184 }, "evidence": [ { "id": "HGNC:29993", "url": "https://alliancegenome.org/gene/HGNC:29993#orthology", "database": "AGR" }, { "id": "MGI:1920864", "url": "https://alliancegenome.org/gene/MGI:1920864#orthology", "database": "AGR" }, { "id": "RGD:1586264", "url": "https://alliancegenome.org/gene/RGD:1586264#orthology", "database": "AGR" }, { "id": "FB:FBgn0008636", "url": "https://alliancegenome.org/gene/FB:FBgn0008636#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q96QS3-1", "protein_name": "Homeobox protein ARX", "gene_name": "ARX", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSNQYQEEGCSERPECKSKSPTLLSSYCIDSILGRRSPCKMRLLGAAQSLPAPLTSRADPEKAVQGSPKSSSAPFEAELHLPPKLRRLYGPGGGRLLQGAAAAAAAAAAAAAAAATATAGPRGEAPPPPPPTARPGERPDGAGAAAAAAAAAAAAWDTLKISQAPQVSISRSKSYRENGAPFVPPPPALDELGGPGGVTHPEERLGVAGGPGSAPAAGGGTGTEDDEEELLEDEEDEDEEEELLEDDEEELLEDDARALLKEPRRCPVAATGAVAAAAAAAVATEGGELSPKEELLLHPEDAEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKREKAGAQTHPPGLPFPGPLSATHPLSPYLDASPFPPHHPALDSAWTAAAAAAAAAFPSLPPPPGSASLPPSGAPLGLSTFLGAAVFRHPAFISPAFGRLFSTMAPLTSASTAAALLRQPTPAVEGAVASGALADPATAAADRRASSIAALRLKAKEHAAQLTQLNILPGTSTGKEVC", "length": 562 }, "evidence": [ { "id": "HGNC:18060", "url": "https://alliancegenome.org/gene/HGNC:18060#orthology", "database": "AGR" }, { "id": "RGD:1562672", "url": "https://alliancegenome.org/gene/RGD:1562672#orthology", "database": "AGR" }, { "id": "MGI:1097716", "url": "https://alliancegenome.org/gene/MGI:1097716#orthology", "database": "AGR" }, { "id": "FB:FBgn0008636", "url": "https://alliancegenome.org/gene/FB:FBgn0008636#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9BQY4-1", "protein_name": "Rhox homeobox family member 2", "gene_name": "RHOXF2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPPDQCSQYMTSLLSPAVDDEKELQDMNAMVLSLTEEVKEEEEDAQPEPEQGTAAGEKLKSAGAQGGEEKDGGGEEKDGGGAGVPGHLWEGDLEGTSGSDGNVEDSDQSEKEPGQQYSRPQGAVGGLEPGNAQQPNVHAFTPLQLQELERIFQREQFPSEFLRRRLARSMNVTELAVQIWFENRRAKWRRHQRALMARNMLPFMAVGQPVMVTAAEAITAPLFISGMRDDYFWDHSHSSSLCFPMPPFPPPSLPLPLMLLPPMPPAGQAEFGPFPFVIVPSFTFPNV", "length": 288 }, "evidence": [ { "id": "HGNC:30011", "url": "https://alliancegenome.org/gene/HGNC:30011#orthology", "database": "AGR" }, { "id": "FB:FBgn0008636", "url": "https://alliancegenome.org/gene/FB:FBgn0008636#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9ERS8-1", "protein_name": "Homeobox protein SEBOX", "gene_name": "Sebox", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASPVEASPGCASGLGPHRRKRTTFSVGQLLELERVFAARPYPDISTREHLAQITHLPEAKIQVWFQNRRAKRIKDRKPGALNARLELPPNCSLPDTPQLSWDPGTPSHPLHSTSSAQQTSACPPQTSCLAPILGPGQSWSGAKAAAPWGTSEVSGVHSLEQIVPQTSLGNLSDLIYTSAIVTNVDHS", "length": 188 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-021206-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-021206-4#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9H161-1", "protein_name": "Homeobox protein aristaless-like 4", "gene_name": "ALX4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNAETCVSYCESPAAAMDAYYSPVSQSREGSSPFRAFPGGDKFGTTFLSAAAKAQGFGDAKSRARYGAGQQDLATPLESGAGARGSFNKFQPQPSTPQPQPPPQPQPQQQQPQPQPPAQPHLYLQRGACKTPPDGSLKLQEGSSGHSAALQVPCYAKESSLGEPELPPDSDTVGMDSSYLSVKEAGVKGPQDRASSDLPSPLEKADSESNKGKKRRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWFQNRRAKWRKRERFGQMQQVRTHFSTAYELPLLTRAENYAQIQNPSWLGNNGAASPVPACVVPCDPVPACMSPHAHPPGSGASSVTDFLSVSGAGSHVGQTHMGSLFGAASLSPGLNGYELNGEPDRKTSSIAALRMKAKEHSAAISWAT", "length": 411 }, "evidence": [ { "id": "HGNC:450", "url": "https://alliancegenome.org/gene/HGNC:450#orthology", "database": "AGR" }, { "id": "MGI:108359", "url": "https://alliancegenome.org/gene/MGI:108359#orthology", "database": "AGR" }, { "id": "RGD:1310201", "url": "https://alliancegenome.org/gene/RGD:1310201#orthology", "database": "AGR" }, { "id": "FB:FBgn0008636", "url": "https://alliancegenome.org/gene/FB:FBgn0008636#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9HB31-1", "protein_name": "Homeobox protein SEBOX", "gene_name": "SEBOX", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPSPVDASSADGGSGLGSHRRKRTTFSKGQLLELERAFAAWPYPNISTHEHLAWVTCLPEAKVQVWFQKRWAKIIKNRKSGILSPGSECPQSSCSLPDTLQQPWDPQMPGQPPPSSGTPQRTSVCRHSSCPAPGLSPRQGWEGAKAVAPWGSAGASEVHPSLERATPQTSLGSLSDLIYALAIVVNVDHS", "length": 190 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-021206-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-021206-4#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VWH1-1", "protein_name": "Homeobox domain-containing protein", "gene_name": "CG14203", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MIRATSCALSTRPLRSPKAPSHRHKIRSIKTGARSPRDSFQLDYSIDFFKTYIDTQRFYAGHKLDFKHQSCAGGPGSGGAGGPGPGGGGGASGVVVVGGTSNSNNPAAAQQQQQQQQQQQQQQQQQSGGNNPSNGSNSAVALSLAHPHAHASHAHSSHAHGSHAHALAIAHGHHGLLPSVVPQQQQQQQQQQQQQQQQQQAQQLPPGVGVASPLQQQQQQQQQQQQQQQQQQQQQQLINNGGVSAGTPTLLIGNGPSSSGAGTGSVSAAAAAAAAAAAASSSSSSLPHVAPHSLGLSPQSSADSQQFNIFPAIFSRQLNFSAGGQGGKLSMDELRPNLVGGLLGLQQGLLEDHASMQHGGVGQDTKFMSFQDQRLMGIGGSHENRLLSLASSVQDTRSPITTLEKSSSSSLNHQRKCSSTPEDFSALYSGLPTPGMDSSSHHHTPAHTPPSRLSDHTISAEGAFKKLKPEPNSGLSTVSAGITSPGSGLSSLSQHAGHTPTTASCPTPARRRHRTTFTQEQLAELEAAFAKSHYPDIYCREELARTTKLNEARIQVWFQNRRAKYRKQEKQLQKALAPSVIPSCNGMMRNIQGYSVSRGYQPYPHHNTMNRYPQDLFQMGASSYPGMTQPFSMAHSTNMGSVGVRQDSMGEFHGMSPEDEWYNKSLSALRMNSSHHPNLSAPMLQYQT", "length": 688 }, "evidence": [ { "id": "HGNC:30011", "url": "https://alliancegenome.org/gene/HGNC:30011#orthology", "database": "AGR" }, { "id": "HGNC:33519", "url": "https://alliancegenome.org/gene/HGNC:33519#orthology", "database": "AGR" }, { "id": "HGNC:14865", "url": "https://alliancegenome.org/gene/HGNC:14865#orthology", "database": "AGR" }, { "id": "HGNC:29993", "url": "https://alliancegenome.org/gene/HGNC:29993#orthology", "database": "AGR" }, { "id": "RGD:1586264", "url": "https://alliancegenome.org/gene/RGD:1586264#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9XZU0-1", "protein_name": "PvuII-PstI homology 13", "gene_name": "Pph13", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDKGTMKRKQRRYRTTFNTLQLQELERAFQRTHYPDVFFREELAVRIDLTEARVQVWFQNRRAKWRKQEKIGGLGGDYKEGALDLDVSYDDSAVLGQLDSALGGGGTLLPDTPPQSSNSLDNELKASYGTGAMSPSRLSPNIFLNLNIDHLGLERGGSGLSMEWSTYPPQTQAQTHPQMDSDNQLQQHPPQQHASDPIHAGSSSHHQQQQQQHQQEQHNPQLHPGLEFAASLSLDMTDGSSAYDEMKFLSVDVDQFTIDSFKADCILSMEQSQMQAYGGHSQLVGSSNELCLDGIGMSSFGMEEGEPKSPPSLLVLDKSLPSLSIGVEGIADLVEQLHHHQHEGGPVGGGVITGDVM", "length": 357 }, "evidence": [ { "id": "HGNC:1494", "url": "https://alliancegenome.org/gene/HGNC:1494#orthology", "database": "AGR" }, { "id": "HGNC:449", "url": "https://alliancegenome.org/gene/HGNC:449#orthology", "database": "AGR" }, { "id": "HGNC:30011", "url": "https://alliancegenome.org/gene/HGNC:30011#orthology", "database": "AGR" }, { "id": "HGNC:33519", "url": "https://alliancegenome.org/gene/HGNC:33519#orthology", "database": "AGR" }, { "id": "HGNC:14865", "url": "https://alliancegenome.org/gene/HGNC:14865#orthology", "database": "AGR" }, { "id": "HGNC:450", "url": "https://alliancegenome.org/gene/HGNC:450#orthology", "database": "AGR" }, { "id": "HGNC:29993", "url": "https://alliancegenome.org/gene/HGNC:29993#orthology", "database": "AGR" }, { "id": "MGI:108359", "url": "https://alliancegenome.org/gene/MGI:108359#orthology", "database": "AGR" }, { "id": "MGI:1920864", "url": "https://alliancegenome.org/gene/MGI:1920864#orthology", "database": "AGR" }, { "id": "MGI:104621", "url": 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"https://prosite.expasy.org/PRU00108" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000259", "start_pos": 151, "end_pos": 211, "start_aa": "Arg", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 358 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 325, "end_pos": 327 }, { "start_pos": 344, "end_pos": 346 }, { "start_pos": 396, "end_pos": 398 }, { "start_pos": 80, "end_pos": 82 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", 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"site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9W2T3-1", "uniprot_ac": "Q9W2T3", "uniprot_id": "Q9W2T3_DROME", "mass": { "chemical_mass": 73505.0, "monoisotopic_mass": 73505.0 }, "refseq": { "ac": "NP_572638", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572638" }, "gene_names": [ { "name": "Dmel\\CG2124", "type": "recommended", "evidence": [ { "id": "Q9W2T3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W2T3" } ] }, { "name": "CG2124", "type": "synonym", "evidence": [ { "id": "NP_572638", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572638" }, { "id": "Q9W2T3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W2T3" } ] }, { "name": "Dmel\\CG2124", "type": "synonym", "evidence": [ { "id": "NP_572638", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572638" } ] }, { "name": "Dmel_CG2124", "type": "synonym", "evidence": [ { "id": "Q9W2T3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W2T3" } ] } ], "protein_names": [ { "name": "RAP domain-containing protein", "type": "recommended", "evidence": [ { "id": "Q9W2T3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W2T3/entry#names_and_taxonomy" } ] }, { "name": "CG2124-PA", "type": "synonym", "evidence": [ { "id": "NP_572638", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572638" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_572638", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572638" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W2T3", "url": "https://www.uniprot.org/uniprotkb/Q9W2T3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG2124", "url": "https://www.uniprot.org/uniprotkb/Q9W2T3", "locus": { "chromosome": "X", "start_pos": 10599169, "end_pos": 10596122, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0030217", "url": "https://www.ensemblgenomes.org/id/FBgn0030217" } ] } } ], "crossref": [ { "id": "FB:FBgn0030217", "url": "https://alliancegenome.org/gene/FB:FBgn0030217", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0030217", "url": "https://bgee.org/?page=gene&gene_id=FBgn0030217", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0030217", "url": "https://flybase.org/reports/FBgn0030217", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "31989", "url": "https://www.ncbi.nlm.nih.gov/gene/31989", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013584", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013584", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG2124", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG2124", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IAGWNNV", "url": "https://omabrowser.org/oma/group/IAGWNNV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W2T3", "url": "https://www.orthodb.org/?gene=Q9W2T3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "NP_572638", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572638", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W2T3", "url": "https://www.uniprot.org/uniprotkb/Q9W2T3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W2T3-1", "url": "https://www.uniprot.org/uniprotkb/Q9W2T3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWARTNYLWRSVGRLRRQVCTTIVSPARIFADRENQFAHGILMDSLKPYAILRPRDSAWQDLPASEGFMRPQPDASAADLYADFLGLVRHCNRMELKISDSRYEAFTRCFCEQLHRLTDEQLLGSLSALAELPVPESPKAKNYMEIWNTLDIECCRRIERWSSEQLLLVSDAWYRLGLVRIGEYVWLALKKLGRKLRKLPPEQLVHSMFLCNLLRRPVFEMFDFELNLARCVDQMTLSELGVMAMGFFKTQTPIRNPELLTQLYQRLGSELDTVEDIVLVALLKVLRYSSKLPQVEPLKKMLSALESQVDRVSLLTCLHMALLGCELQTCNDALVERILLRFERELETARLKDMERICLVMALFNITTKSGVERRLAERLPDLLRQRIEEILRHPRCFSNCLQFLTMRGVYDLELLGVALEPRFLKHAYPSGLPGREYFHLDGFARLLGPEYQGALVTEKQRQQMGRNYTQYIPDRDGRFKLNNTDRILVEIRDAITMIHRPVTFKHILPQYDRCDVVLCYDRRQRKALSINGEACQDYSGEILTRKHLLGERKAADDQLVTVVIVIAGWNNVIRDKDRFTGQMDMKLRQLRQLGHQPLVIYWHEWRELENSADRQDFLKRRLSQIAKI", "length": 629, "header": "tr|Q9W2T3-1|Q9W2T3_DROME Isoform 1 of RAP domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG2124 PE=4 SV=1 CANONICAL=Q9W2T3-1" }, "isoforms": [ { "isoform_ac": "Q9W2T3-1", "url": "https://www.uniprot.org/uniprotkb/Q9W2T3/entry#Q9W2T3-1", "sequence": { "sequence": "MWARTNYLWRSVGRLRRQVCTTIVSPARIFADRENQFAHGILMDSLKPYAILRPRDSAWQDLPASEGFMRPQPDASAADLYADFLGLVRHCNRMELKISDSRYEAFTRCFCEQLHRLTDEQLLGSLSALAELPVPESPKAKNYMEIWNTLDIECCRRIERWSSEQLLLVSDAWYRLGLVRIGEYVWLALKKLGRKLRKLPPEQLVHSMFLCNLLRRPVFEMFDFELNLARCVDQMTLSELGVMAMGFFKTQTPIRNPELLTQLYQRLGSELDTVEDIVLVALLKVLRYSSKLPQVEPLKKMLSALESQVDRVSLLTCLHMALLGCELQTCNDALVERILLRFERELETARLKDMERICLVMALFNITTKSGVERRLAERLPDLLRQRIEEILRHPRCFSNCLQFLTMRGVYDLELLGVALEPRFLKHAYPSGLPGREYFHLDGFARLLGPEYQGALVTEKQRQQMGRNYTQYIPDRDGRFKLNNTDRILVEIRDAITMIHRPVTFKHILPQYDRCDVVLCYDRRQRKALSINGEACQDYSGEILTRKHLLGERKAADDQLVTVVIVIAGWNNVIRDKDRFTGQMDMKLRQLRQLGHQPLVIYWHEWRELENSADRQDFLKRRLSQIAKI", "length": 629, "header": "tr|Q9W2T3-1|Q9W2T3_DROME Isoform 1 of RAP domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG2124 PE=4 SV=1 CANONICAL=Q9W2T3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W2T3", "url": "https://www.uniprot.org/uniprotkb/Q9W2T3" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W2T3", "url": "https://www.uniprot.org/uniprotkb/Q9W2T3" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2T3", "url": "https://www.uniprot.org/uniprotkb/Q9W2T3" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2T3", "url": "https://www.uniprot.org/uniprotkb/Q9W2T3" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W2T3", "url": "https://www.uniprot.org/uniprotkb/Q9W2T3" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W2T3", "url": "https://www.uniprot.org/uniprotkb/Q9W2T3" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W2T3", "url": "https://www.uniprot.org/uniprotkb/Q9W2T3" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2T3", "url": "https://www.uniprot.org/uniprotkb/Q9W2T3" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2T3", "url": "https://www.uniprot.org/uniprotkb/Q9W2T3" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W2T3", "url": "https://www.uniprot.org/uniprotkb/Q9W2T3" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W2T3", "url": "https://www.uniprot.org/uniprotkb/Q9W2T3" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG2124", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG2124", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AAM0-1", "protein_name": "FAST kinase domains 5", "gene_name": "Fastkd5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSATLKLLKLLKYKASCNPSAYHAAQSMAYWPMENIAQHGGQNLPKHNSSCHLARKVKNIGDTTLSQRAFTTSSAHLGLEFNKASALKASALHPDSPSARRGEEDVEVFDSFEGTRVFLKLRPEYQLHSYNRSETRQPLSASEGELILHKVTFYEDKLQPEVITNYFCKLSSLPAEQSSVLLCSNSFALLCHQSVRNIQLFNTSDLVSILKAFVDLRIPFSASMLDVYETRFCHQVWGMNLDQLLLVADLWRNLGRRVPRFLKIFFSYLNLHWRELSLSQLIHLIYIIGENRQVPQDLMQKLESLILKYIDSVNLEEVGTICLGFFKSSTSLSEFVMRKIGDLACANMQDVRSHTLVHILKMFRFTHVDHVNFMRQFGEIAPQRIPSLGVQGVMHLTLACSALRILDERVMNAVAASLPPRVAHCRSKDVAKILWSFGTLNYKPPNTEEFYSSLINEIHRKMPEFNQYPEHLLTCLIGLAFSEYFPAEFINVALSPGFVKLAQMRSKFELTKELFTLDGTVAIECPDYKGNRLNSHLQQEASANLWSLANKDMRSKPEFLETLYLLETMLGGPQYIKHHMILPHTRSSDLEVQLDANMKPLPFNSEATPTEDVAQLRLKQVGVSLTDDLMNQLLKGKAKRYFQGETELETGQLSIELRKKTTVPLVDSDCNGADRLGDTGIAGLCPLTHMQTPLVKLAIQFTNKNQYCYGSRDLLGLHNMKRRQLVQIGYRVVELPHWEWLPLLKRTRLEKLAYLHEKVFTSAL", "length": 764 }, "evidence": [ { "id": "MGI:2139469", "url": "https://alliancegenome.org/gene/MGI:2139469#orthology", "database": "AGR" }, { "id": "HGNC:25790", "url": "https://alliancegenome.org/gene/HGNC:25790#orthology", "database": "AGR" }, { "id": "RGD:1563839", "url": "https://alliancegenome.org/gene/RGD:1563839#orthology", "database": "AGR" }, { "id": "FB:FBgn0030217", "url": "https://alliancegenome.org/gene/FB:FBgn0030217#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7L8L6-1", "protein_name": "Non-canonical pre-mRNAs endonuclease FASTKD5, mitochondrial", "gene_name": "FASTKD5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAATLKSLKLVRYRAFCSPSAFGAVRSVSYWNVSSTQHGGQDPPEHISLCHSAKKVKNICSTFSSRRILTTSSAHPGLEFSKTSSSKASTLQLGSPRATGVDEEDVEVFDSFENMRVFLQLRPEYRVHSYNASETSQLLSVSEGELILHKVRVNQNNLQAQVIVDYLCKLSSLPAEQHPVLLGSTSFALLCQLSVKKIQLFDTQDLINVLKAFVILGIPHSHSMLDVYETKCCHQVWEMNMDQLLLVADLWRYLGRKVPRFLNIFSSYLNLHWKDLSLSQLVHLIYVIGENRQVSQDLMQKLESLILKYIDLINLEEVGTICLGFFKSSTNLSEFVMRKIGDLACANIQHLSSRSLVNIVKMFRFTHVDHINFMKQIGEIAPQRIPSLGVQGVMHLTLYCSALRFLNEGVMNAVAASLPPRVAHCRSKDVAKILWSFGTLNYKPPNAEEFYSSLISEIHRKMPEFNQYPEHLPTCLLGLAFLEYFPVELIDFALSPGFVRLAQERTKFDLLKELYTLDGTVGIECPDYRGNRLSTHLQQEGSELLWYLAEKDMNSKPEFLETVFLLETMLGGPQYVKHHMILPHTRSSDLEVQLDVNLKPLPFNREATPAENVAKLRLEHVGVSLTDDLMNKLLKGKARGHFQGKTESEPGQQPMELENKAAVPLGGFLCNVADKSGAMEMAGLCPAACMQTPRMKLAVQFTNRNQYCYGSRDLLGLHNMKRRQLARLGYRVVELSYWEWLPLLKRTRLEKLAFLHEKVFTSAL", "length": 764 }, "evidence": [ { "id": "MGI:2139469", "url": "https://alliancegenome.org/gene/MGI:2139469#orthology", "database": "AGR" }, { "id": "HGNC:25790", "url": "https://alliancegenome.org/gene/HGNC:25790#orthology", "database": "AGR" }, { "id": "RGD:1563839", "url": "https://alliancegenome.org/gene/RGD:1563839#orthology", "database": "AGR" }, { "id": "FB:FBgn0030217", "url": "https://alliancegenome.org/gene/FB:FBgn0030217#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TMV3-1", "protein_name": "Non-canonical pre-mRNAs endonuclease FASTKD5, mitochondrial", "gene_name": "Fastkd5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAALKLLEPLKYKAPCNPAYRAAQSVAHWHMGNITPHGGQTLPECNSSCHLARKVKNVGGTTLPRRTFTASSAHLGLEFNKASTLNASTLHPDSSSAGGGEEDVEVFDSFEGTRVFLKLRPEYQLHSYNRSDTHQPIAASEVELILHKVTFYQNKLQPEVITNYFYKLSSLPAEQNSVLLSSNSFALLCQLSVKNIQLFNTSDLISILKAFVDLRIPPSLSMLDVYETRFCHQVWEMTLDQLLLVADLWRNLGRRVPRFFKIFFSYLNLHWRELSLSQLIHLIYIIGENRQVPQDLMQRLESLILKYVDSVNLEEVGTICLGFFKSSSSLSEFVMRKIGDLACANMQHLSSHTLVHILKMFRFTHVDHIHFMKQFGEIAPQRIPSLGVQGVMHLTLACSALRILDERVMNAVAASLPPRVAHCRSKDVAKILWSFGTLNYKPPNTEEFYSSLINEIHRKMPEFNQYPEHLLTCLIGLAFSEYFPVEFINVALSPGFVKLAQERSKFELTKELFTLDGTVAIECPDYKGNRLNSHLQQETSANLWNLASKDMRSKPEFLETLYLLETMLGGPQYIKHHMILPHTRSSDLEVQLDANMKPMPFNSEATPTEDGAQLRFKQVGVSLTDDLMNQLLKGKAKRYFQGQIELETGQPPMELRKKTTVPLVNSGCNGTDRLGDGMVGLCPLAHMQPPLVKLAIQFTNKNQYCYGSRALLGLHNMKRRQLVQIGYRVVELPHWEWLPLLKRTRLEKLAYLHEKVFTSAL", "length": 762 }, "evidence": [ { "id": "MGI:2139469", "url": "https://alliancegenome.org/gene/MGI:2139469#orthology", "database": "AGR" }, { "id": "HGNC:25790", "url": "https://alliancegenome.org/gene/HGNC:25790#orthology", "database": "AGR" }, { "id": "RGD:1563839", "url": "https://alliancegenome.org/gene/RGD:1563839#orthology", "database": "AGR" }, { "id": "FB:FBgn0030217", "url": "https://alliancegenome.org/gene/FB:FBgn0030217#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mitochondrial RNA processing", "id": "GO:0000963", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000963", "evidence": [ { "database": "UniProtKB", "id": "Q9W2T3", "url": "https://www.uniprot.org/uniprotkb/Q9W2T3" } ], "pmid": "" }, { "name": "regulation of mitochondrial mRNA stability", "id": "GO:0044528", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044528", "evidence": [ { "database": "UniProtKB", "id": "Q9W2T3", "url": "https://www.uniprot.org/uniprotkb/Q9W2T3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", 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"MSTFGAEVDQVWPAVTGDSPHLTNFGRKLLKDCRQVQKPIGGYENLGNVIKLSAEFPLEFGVNSVKVYRQSPSRLARINEEVASAYPLIHERTLGLYLQYLEHKCRWGNAVEKPIYRNLSLCGFVQRLLVKRCASFFARNDKYLLVSGESGASGFEAVGTREEKAPLVLANVLSYDDIKLSALLSVSSRTEFVNEGERTNCGHVDLNTKTLERHGVIVGMIGARLSRRNLMEFQDIVIARQQNTRERGYGMALDEPATTRDEDYRRLWREFYATRDLIHGQAVIDNQRFGPSKNKMDVFDNLVMKRRYAISFDMLLLEAEARAKRVKKLAYIHVVGFGLGVWKAAEQQERIFMETFEQRMRTLGNRLNNVGLVHFSWFSITHCGGLSNGSLIEIPGHPKDGIRVLISKRNPARKLSDPEHAGMLLVVSYAWDGNALPGNEFWMKMLQSTGDSSTACSTLVAELHNPYINTKFCNGGNLHIASPEHGVLHIAEYAKRVIRSESDAL", "length": 505, "header": "sp|Q9W2W5-1|ADPR1_DROME Isoform 1 of ADP-ribosylarginine hydrolase CG2909 OS=Drosophila melanogaster OX=7227 GN= PE=1 SV=1 CANONICAL=Q9W2W5-1" }, "isoforms": [ { "isoform_ac": "Q9W2W5-1", "url": "https://www.uniprot.org/uniprotkb/Q9W2W5/entry#Q9W2W5-1", "sequence": { "sequence": 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"https://www.ensemblgenomes.org/id/FBpp0071376" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W2W5", "url": "https://www.uniprot.org/uniprotkb/Q9W2W5" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "A Drosophila full-length cDNA resource.", "journal": "Genome Biol.", "date": "2002", "authors": "Stapleton M, Carlson J, Brokstein P, Yu C, Champe M, George R, Guarin H, Kronmiller B, Pacleb J, Park S, Wan K, Rubin GM, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2W5", "url": "https://www.uniprot.org/uniprotkb/Q9W2W5" } ], "reference": [ { "type": "PubMed", "id": "12537569", "url": "https://glygen.org/publication/PubMed/12537569" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2W5", "url": "https://www.uniprot.org/uniprotkb/Q9W2W5" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "Legionella metaeffector MavL reverses ubiquitin ADP-ribosylation via a conserved arginine-specific macrodomain.", "journal": "Nature communications", "date": "2024-03-19", "authors": "Zhang Zhengrui, Fu Jiaqi, Rack Johannes Gregor Matthias, Li Chuang, Voorneveld Jim, Filippov Dmitri V, Ahel Ivan, Luo Zhao-Qing, Das Chittaranjan", "evidence": [ { "database": "UniProtKB", "id": "Q9W2W5", "url": "https://www.uniprot.org/uniprotkb/Q9W2W5" } ], "reference": [ { "type": "PubMed", "id": "38503748", "url": "https://glygen.org/publication/PubMed/38503748" } ] } ], "pathway": [ { "id": "dme:Dmel_CG2909", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG2909", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ADP-ribosylarginine hydrolase activity", "id": "GO:0003875", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003875", "evidence": [ { "database": "UniProtKB", "id": "Q9W2W5", "url": "https://www.uniprot.org/uniprotkb/Q9W2W5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 118, "end_pos": 120, "annotation": 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Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W2Y4", "url": "https://www.uniprot.org/uniprotkb/Q9W2Y4" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W2Y4", "url": "https://www.uniprot.org/uniprotkb/Q9W2Y4" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2Y4", "url": "https://www.uniprot.org/uniprotkb/Q9W2Y4" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2Y4", "url": "https://www.uniprot.org/uniprotkb/Q9W2Y4" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W2Y4", "url": "https://www.uniprot.org/uniprotkb/Q9W2Y4" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W2Y4", "url": "https://www.uniprot.org/uniprotkb/Q9W2Y4" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W2Y4", "url": "https://www.uniprot.org/uniprotkb/Q9W2Y4" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2Y4", "url": "https://www.uniprot.org/uniprotkb/Q9W2Y4" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2Y4", "url": "https://www.uniprot.org/uniprotkb/Q9W2Y4" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W2Y4", "url": "https://www.uniprot.org/uniprotkb/Q9W2Y4" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W2Y4", "url": "https://www.uniprot.org/uniprotkb/Q9W2Y4" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG2972", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG2972", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MDA9-1", "protein_name": "RNA-binding protein NOB1", "gene_name": "NOB1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAPVEHVVADAGAFLLDAALQDIGKNIYTIRNVISEIRDKATRRRLAVLPYELRFKEPFPEYVRLVTEFSKKTGDYPSLSATDIQVLALTYQLEAEFVGVSHLKQEPEKVKVSSSIQHPETPLHVSGFHLPSKPKPPRETVEHRHPASEPEDLEFSSFMFWRNPLPNIDCELQELLMDGGEDVPNEEEDEENGLDERQDQDSDDDGGGWITPSNIKQIQQEMKQCAVPKDVRVGCVTTDFAMQNVLLQMGLHVLAVNGMLIREARSYILRCHGCFKTTSDMSRVFCAHCGNKTLKKVSVTVSDDGTLHMHFSRNPKVLNPRGLRYSLPTPKGGKYAINPHLTEDQRFPQLRLSRKARQKTDVFAPDYVAGVSPFAENDISSRSATLQVRDSTLGAGRRRLNPNASRKKFVKKR", "length": 413 }, "evidence": [ { "id": "Q9W2Y4", "url": "https://omabrowser.org/oma/group/Q9W2Y4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1NRU5-1", "protein_name": "RNA-binding protein NOB1", "gene_name": "NOB1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MARVPHVVADAGAFLSGAALQDVAQSVYTVPEVLAEIRDRRARRRLAALPYELQLRRPRADFVRTVTEFAKRTGDFPSLSAADLQVLALTCQLQAETAGPGSVRLQPPDKVRLSSSPRHPEATLHLAGFHLPAKHKRPRKGRQQHGPDSSTELPDNAEFGSFLYWRPPLPSIEDELQEMLKTHSISSSPAATDELQNSEDGDGAEEEEDDEEESDDDNEGWITPSNLKQVQQDTGHCDTVPANVQVGCVTTDFSMQNVLLQMGLHVLAVNGMLIRQARSHILRCHGCFRTTSDMTKVFCPHCGNKTLKKVAVSVSEDGSLHMHFSRNPKVLNPRGLRYPLPAPQGGKHANNPHLVEDQPFPQQRLSRKARQKTNVFDPDYVAGVSPFAENDIYSRAANLQIRDRALGAGRRRLNPNAVTKKFVKRR", "length": 426 }, "evidence": [ { "id": "Q9W2Y4", "url": "https://omabrowser.org/oma/group/Q9W2Y4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1S396-1", "protein_name": "RNA-binding protein NOB1", "gene_name": "NOB1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAPVEHVVADAGAFLQNAALQDIGKNIYTIRDVVSEIRDKATRRRLAVLPYELRFKEPFPEYVRLVTEFSKKTGDYPSLSATDIQVLALTYQLEAEFVGVSHLKQEPEKVKVSSSSQHPETPLHISGFHLPSKPKRPQETVEHGEPARASEDLEFTSFVFWRNPLPDIDRDLQELLIDGGGCVPSEEEKEEDGLEEGKDQDSDDDGGGWITPSNIKQIQQELERCSVPKDVRVGCVTTDFAMQNVLLQMGLHVLAVNGMLIREARSYILRCHGCFKTTSDMSRVFCSHCGNKTLKKVSVTVSDDGTLHMHFSRNPKVLNPRGLRYSLPAPKGGKYAINPHLTEDQRFPQLRLSRKARQKTDVFAPDYVAGVSPFAENDISSRSATLQVRDSTLGAGRRRLNPNASRKKFVKKR", "length": 413 }, "evidence": [ { "id": "Q9W2Y4", "url": "https://omabrowser.org/oma/group/Q9W2Y4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3ISV3-1", "protein_name": "RNA-binding protein NOB1", "gene_name": "nob1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVATIVEHVVVDAGAFIKRAPLHEIGKNIYTLKDVVDEIRDKPTKRSLAFLPYKLDFKEPFPEYIQFVTEFAKKTGDYPSLSATDIKVLALTYQLESENVGTEHLKKEPEKQVQICSTQRHPETPVGIAGFHFPSKSSGKSAIQSPPTTNEPHDPVSSQFNTFQFWRNPLPSIESELLELLAADAITVTQKLESVNLSAESEEHEGNNGEQHEEEEEEEFNSDDEEEEEDDEDGGGWITPSNIKQVQMDAGVRGPSADVKVGCVTTDFAMQNVLIQIGLNVLSVNGMLIKNTRSYILRCHACFKTTTNMNKSFCPNCGNNTLKKIAVTLNEDGTMQMHFSRNPKVLNPKGKRYSLPMPQGGKHGNNPHLVEDQRFPQQRMSRKARQKTNVFDPDYLASSSPFSEHDVYSKSASLQLRDGQTGGGRRRTNPNAARKKFVKK", "length": 440 }, "evidence": [ { "id": "MGI:1914869", "url": "https://alliancegenome.org/gene/MGI:1914869#orthology", "database": "AGR" }, { "id": "HGNC:29540", "url": "https://alliancegenome.org/gene/HGNC:29540#orthology", "database": "AGR" }, { "id": "Q9W2Y4", "url": "https://omabrowser.org/oma/group/Q9W2Y4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q08444-1", "protein_name": "20S-pre-rRNA D-site endonuclease NOB1", "gene_name": "NOB1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTENQTAHVRALILDATPLITQSYTHYQNYAQSFYTTPTVFQEIKDAQARKNLEIWQSLGTLKLVHPSENSIAKVSTFAKLTGDYSVLSANDLHILALTYELEIKLNNGDWRLRKKPGDALDASKADVGTDGKQKLTEDNKKEEDSESVPKKKNKRRGGKKQKAKREAREAREAENANLELESKAEEHVEEAGSKEQICNDENIKESSDLNEVFEDADDDGDWITPENLTEAIIKDSGEDTTGSLGVEASEEDRHVALNRPENQVALATGDFAVQNVALQMNLNLMNFMSGLKIKRIRNYMLRCHACFKIFPLPKDGKPKHFCASCGGQGTLLRCAVSVDSRTGNVTPHLKSNFQWNNRGNRYSVASPLSKNSQKRYGKKGHVHSKPQENVILREDQKEYEKVIKQEEWTRRHNEKILNNWIGGGSADNYISPFAITGLKQHNVRIGKGRYVNSSKRRS", "length": 459 }, "evidence": [ { "id": "RGD:735222", "url": "https://alliancegenome.org/gene/RGD:735222#orthology", "database": "AGR" }, { "id": "MGI:1914869", "url": "https://alliancegenome.org/gene/MGI:1914869#orthology", "database": "AGR" }, { "id": "HGNC:29540", "url": "https://alliancegenome.org/gene/HGNC:29540#orthology", "database": "AGR" }, { "id": "FB:FBgn0030177", "url": "https://alliancegenome.org/gene/FB:FBgn0030177#orthology", "database": "AGR" }, { "id": "SGD:S000005582", "url": "https://alliancegenome.org/gene/SGD:S000005582#orthology", "database": "AGR" }, { "id": "Q9W2Y4", "url": "https://omabrowser.org/oma/group/Q9W2Y4/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54W91-1", "protein_name": "RNA-binding protein NOB1", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSEPIENNIVDKQQEEEEEVEYEELTEEQLKELNELNENSNDNPFGERSVTAESDELVKSMETLAMTNEKTTASYLIIDTNALISGTRLETLGKELWTIPEVLEEVKDKKTSTFLTSFPFEIKTRQPTHESMVAVSEFSKKTGDYPSLSATDMKLIALTYTFEAQVNGIDHIKTEPEKLQVVTKKPVHKKNNNNNNNNNNNNKKDNKSESASESNTTTESTTTTTTTTSTATTTTTADKPKKKKNKNKNKKSKPISTDNKNIESTTTDSCCDHKHEEKEEEKVEKVEQVEKVEKVEKVEEEKESVNNNNNNTNNNNDNNNNNITGKKKRNNKLMVNLEKIEEEVSKENLVDPKEVLRQLKIKQAEEAEERKKNRVIKVEDEGEWITPDNIKNKLSSTYVQEKVHYDVGCITRDFSMQNVILQMGLHLISADGVVIKQVKQFVLKCVACLNITTDMDKIFCGHCGNKSLYKATTYVDRNGNQRVSVGSAKQFNLRGTIYSIPKPKGGKKSNDIILTEDQYLHKLRVTGQLYKKKVSKEINMNDLDLGFGHKGPSDDIVIGYGNKNPNVARKRIGKKNKSISIF", "length": 582 }, "evidence": [ { "id": "Q9W2Y4", "url": "https://omabrowser.org/oma/group/Q9W2Y4/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q6VEU1-1", "protein_name": "RNA-binding protein NOB1", "gene_name": "Nob1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPVEHVVADAGAFLRDAPLQDIGKNIYTIREVVREIRDKATRRRLAVLPYELRFKEPFPEYVRLVTEFSKKTGDYPSLSATDIQVLALTYQLEAEFVGVSHLKKEPEKVKVSSSIQHPETPLHISGFHLPSKSKALQETVDHGPPADGSENLEFSSFMFWRNPLPNIDHELQQLLIDGREEEEEEEEEEEEEDELEDSDDDGGGWITPSNIKQIQHESEQCDIPKDVQVGCVTTDFAMQNVLLQMGLHVLAVNGMLVREARSYILRCHGCFKTTSDMNRVFCGHCGNKTLKKVSVTINDDGTLHMHFSRNPKVLNPRGLRYSLPTPKGGKYAVNPHLTEDQRFPQLRLSHKARQKTNVFAPDYIAGVSPFAENDISSRSAILQVRDSMLGAGRRRLNPNASRKKFVKKR", "length": 410 }, "evidence": [ { "id": "RGD:735222", "url": "https://alliancegenome.org/gene/RGD:735222#orthology", "database": "AGR" }, { "id": "MGI:1914869", "url": "https://alliancegenome.org/gene/MGI:1914869#orthology", "database": "AGR" }, { "id": "HGNC:29540", "url": "https://alliancegenome.org/gene/HGNC:29540#orthology", "database": "AGR" }, { "id": "FB:FBgn0030177", "url": "https://alliancegenome.org/gene/FB:FBgn0030177#orthology", "database": "AGR" }, { "id": "SGD:S000005582", "url": "https://alliancegenome.org/gene/SGD:S000005582#orthology", "database": "AGR" }, { "id": "Q9W2Y4", "url": "https://omabrowser.org/oma/group/Q9W2Y4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BW10-1", "protein_name": "RNA-binding protein NOB1", "gene_name": "Nob1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPVEHVVADAGAFLRDAPLQDIGKNIYTIREVVREIRDKATRRRLAVLPYQLRFKEPLPEYVRLVTEFSKKTGDYPSLSATDIQVLALTYQLEAEFVGVSHLKKEPEKAKVSSSIQHPETALHISGFHLPSKSKPLQEAVDRGHAADGPENLEFSSFMFWRTPLPNIDRELQELLIDGREEEEEEEECEDSDDDGGGWITPSNIKQIQQELEQCDTPEDVQVGCVTTDFAMQNVLLQMGLHVLAVNGMLVREARSYILRCHGCFKTTSDMNRVFCGHCGNKTLKKVSVTINDDGTLHMHFSRNPKVLNPRGLRYSLPTPKGGKYAINPHLTEDQRFPQLRLSQKARQKTDVFAPDYIAGVSPFAENDISSRSAILQVRDGMLGAGRRRLNPNASRKKFVKKR", "length": 403 }, "evidence": [ { "id": "RGD:735222", "url": "https://alliancegenome.org/gene/RGD:735222#orthology", "database": "AGR" }, { "id": "MGI:1914869", "url": "https://alliancegenome.org/gene/MGI:1914869#orthology", "database": "AGR" }, { "id": "HGNC:29540", "url": "https://alliancegenome.org/gene/HGNC:29540#orthology", "database": "AGR" }, { "id": "FB:FBgn0030177", "url": "https://alliancegenome.org/gene/FB:FBgn0030177#orthology", "database": "AGR" }, { "id": "SGD:S000005582", "url": "https://alliancegenome.org/gene/SGD:S000005582#orthology", "database": "AGR" }, { "id": "Q9W2Y4", "url": "https://omabrowser.org/oma/group/Q9W2Y4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9FLL1-1", "protein_name": "RNA-binding NOB1-like protein", "gene_name": "NOB1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDPKPTSMWSSIVKKDPPSKPPVNDGAPAAILGMVGNCKSTKGISIAVVDANAIIEGRQSLTNFADKFVTVPEVLSEIRDPASRRRLAFIPFTIDTMEPSPESLSKVIKFARATGDLQSLSDVDLKLIALSYTLEAQVYGTKNLRDVPPPIQTVRVKRLPEKDLPGWGSNVANLEEWEALENETEEKSNANSKILPLKDLNMNIIASDNVSEVGSVVSHTENHEEDVQEGGKKHRRYPPKKTEIKLEGKMVVEGVDASQGQYDDDDDASDWRPAVSRSTHSKYLRRKARWEHYNALAEQEIQKDQEADKARHTKEANETHAKDSGKNGEDISSILKDMRLEEESLRALQEETEETNAEATLINGEDDIDHDIEVEAEGIDVANQALENLEIASEAEDTFEASSIGDDGSSEQSWSLRALSESSVACITGDYAMQNVILQMGLRLLAPGGMQIRQLHRWILKCHACYTVTPEIGRIFCPKCGNGGTLRKVAVTIGANGAIIAACKPRITLRGTQYSIPMPKGGREAITKNLILREDQLPQKLLHPRTKKKASKPGDEYFVSDDVFLNHHSDRKAPLQPPVRKAMSVFSQKRNPNDNHYSRSMH", "length": 602 }, "evidence": [ { "id": "Q9W2Y4", "url": "https://omabrowser.org/oma/group/Q9W2Y4/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9ULX3-1", "protein_name": "RNA-binding protein NOB1", "gene_name": "NOB1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPVEHVVADAGAFLRHAALQDIGKNIYTIREVVTEIRDKATRRRLAVLPYELRFKEPLPEYVRLVTEFSKKTGDYPSLSATDIQVLALTYQLEAEFVGVSHLKQEPQKVKVSSSIQHPETPLHISGFHLPYKPKPPQETEKGHSACEPENLEFSSFMFWRNPLPNIDHELQELLIDRGEDVPSEEEEEEENGFEDRKDDSDDDGGGWITPSNIKQIQQELEQCDVPEDVRVGCLTTDFAMQNVLLQMGLHVLAVNGMLIREARSYILRCHGCFKTTSDMSRVFCSHCGNKTLKKVSVTVSDDGTLHMHFSRNPKVLNPRGLRYSLPTPKGGKYAINPHLTEDQRFPQLRLSQKARQKTNVFAPDYIAGVSPFVENDISSRSATLQVRDSTLGAGRRRLNPNASRKKFVKKR", "length": 412 }, "evidence": [ { "id": "RGD:735222", "url": "https://alliancegenome.org/gene/RGD:735222#orthology", "database": "AGR" }, { "id": "MGI:1914869", "url": "https://alliancegenome.org/gene/MGI:1914869#orthology", "database": "AGR" }, { "id": "HGNC:29540", "url": "https://alliancegenome.org/gene/HGNC:29540#orthology", "database": "AGR" }, { "id": "FB:FBgn0030177", "url": "https://alliancegenome.org/gene/FB:FBgn0030177#orthology", "database": "AGR" }, { "id": "SGD:S000005582", "url": "https://alliancegenome.org/gene/SGD:S000005582#orthology", "database": "AGR" }, { "id": "Q9W2Y4", "url": "https://omabrowser.org/oma/group/Q9W2Y4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nuclear lumen", "id": "GO:0031981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031981", "evidence": [ { "database": "UniProtKB", "id": "Q9W2Y4", "url": "https://www.uniprot.org/uniprotkb/Q9W2Y4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9W2Y4", "url": "https://www.uniprot.org/uniprotkb/Q9W2Y4" } ], "pmid": "" }, { "name": "preribosome, small subunit precursor", "id": "GO:0030688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030688", "evidence": [ { "database": "UniProtKB", "id": "Q9W2Y4", "url": "https://www.uniprot.org/uniprotkb/Q9W2Y4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": 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KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W370", "url": "https://www.uniprot.org/uniprotkb/Q9W370" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W370", "url": "https://www.uniprot.org/uniprotkb/Q9W370" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, 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Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W370", "url": "https://www.uniprot.org/uniprotkb/Q9W370" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W370", "url": "https://www.uniprot.org/uniprotkb/Q9W370" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi 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"InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027413", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027413", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053374", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053374", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG7033", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG7033", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CAEMVMS", "url": "https://omabrowser.org/oma/group/CAEMVMS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W392", "url": "https://www.orthodb.org/?gene=Q9W392", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11353", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11353", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00118", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00118", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-390471", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-390471", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-6814122", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6814122", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-9013418", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9013418", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-9013422", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9013422", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_572524", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572524", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W392", "url": "https://www.uniprot.org/uniprotkb/Q9W392", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W392-1", "url": "https://www.uniprot.org/uniprotkb/Q9W392-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEMSLNPVRVLKNEAQEEKAEMARLSSFIGAIAIGDLVKSTLGPKGMDKILVATGRNAGHVEVTNDGATILRAVGVDNPAAKILVDMSRVQDEEVGDGTTSVTVLASELLREAEKLVEQKLHPQIIVSGWRQATQVALEALTAAAQDNSSSDEKFRNDLLNIARTTLSSKILHQHKDFFANLAVDAVMRLKGSGELKSIQIIKKSGGTLGDSFLDEGFLLDKKPGVHQPQRIENARILIANTPMDTDKIKVFGSSIKVDSLAKIADLEMAEKEKMKEKVDKILKHKCNVFINRQLIYNYPEQLFADARVMSIEHADFDGIERLAYCTGGEIVSTFENPSLVKLGECDVIEQVMIGEDTLLRFSGVKLGEACTIVIRGATQQILDEADRSLHDALCVLAATVKESRIIFGGGCSEALMATAVLKKAAETPGKEAIAIEAFARALLSLPTAIADNAGYDSAQLVSELRAGHAQGKQTLGLDMELGKVADVRELGITESFAVKRQVLMSASEAAEMILRVDNIIRCAPRRRVPDRGYC", "length": 535, "header": "tr|Q9W392-1|Q9W392_DROME Isoform 1 of T-complex protein 1 subunit beta OS=Drosophila melanogaster OX=7227 GN=CCT2 PE=1 SV=2 CANONICAL=Q9W392-1" }, "isoforms": [ { "isoform_ac": "Q9W392-1", "url": "https://www.uniprot.org/uniprotkb/Q9W392/entry#Q9W392-1", "sequence": { "sequence": "MEMSLNPVRVLKNEAQEEKAEMARLSSFIGAIAIGDLVKSTLGPKGMDKILVATGRNAGHVEVTNDGATILRAVGVDNPAAKILVDMSRVQDEEVGDGTTSVTVLASELLREAEKLVEQKLHPQIIVSGWRQATQVALEALTAAAQDNSSSDEKFRNDLLNIARTTLSSKILHQHKDFFANLAVDAVMRLKGSGELKSIQIIKKSGGTLGDSFLDEGFLLDKKPGVHQPQRIENARILIANTPMDTDKIKVFGSSIKVDSLAKIADLEMAEKEKMKEKVDKILKHKCNVFINRQLIYNYPEQLFADARVMSIEHADFDGIERLAYCTGGEIVSTFENPSLVKLGECDVIEQVMIGEDTLLRFSGVKLGEACTIVIRGATQQILDEADRSLHDALCVLAATVKESRIIFGGGCSEALMATAVLKKAAETPGKEAIAIEAFARALLSLPTAIADNAGYDSAQLVSELRAGHAQGKQTLGLDMELGKVADVRELGITESFAVKRQVLMSASEAAEMILRVDNIIRCAPRRRVPDRGYC", "length": 535, "header": "tr|Q9W392-1|Q9W392_DROME Isoform 1 of T-complex protein 1 subunit beta OS=Drosophila melanogaster OX=7227 GN=CCT2 PE=1 SV=2 CANONICAL=Q9W392-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W392", "url": "https://www.uniprot.org/uniprotkb/Q9W392" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W392", "url": "https://www.uniprot.org/uniprotkb/Q9W392" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W392", "url": "https://www.uniprot.org/uniprotkb/Q9W392" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W392", "url": "https://www.uniprot.org/uniprotkb/Q9W392" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W392", "url": "https://www.uniprot.org/uniprotkb/Q9W392" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W392", "url": "https://www.uniprot.org/uniprotkb/Q9W392" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W392", "url": "https://www.uniprot.org/uniprotkb/Q9W392" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W392", "url": "https://www.uniprot.org/uniprotkb/Q9W392" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W392", "url": "https://www.uniprot.org/uniprotkb/Q9W392" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W392", "url": "https://www.uniprot.org/uniprotkb/Q9W392" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W392", "url": "https://www.uniprot.org/uniprotkb/Q9W392" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG7033", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG7033", "resource": "KEGG Pathway" }, { "id": "R-DME-390471", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-390471", "resource": "Reactome", "description": "Association of TriC/CCT with target proteins during biosynthesis" }, { "id": "R-DME-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-DME-6814122", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6814122", "resource": "Reactome", "description": "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" }, { "id": "R-DME-9013418", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9013418", "resource": "Reactome", "description": "RHOBTB2 GTPase cycle" }, { "id": "R-DME-9013422", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9013422", "resource": "Reactome", "description": "RHOBTB1 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "G3HZ42-1", "protein_name": "T-complex protein 1 subunit beta", "gene_name": "Cct2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASLSLAPVNIFKAGADEERAETARLSSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDASLMVTNDGATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQTIIAGWREATKAAREALLTSAVDHGYDEVKFRQDLMNIAGTTLSSKLLTHHKDHFTELAVEAVLRLKGSGNLEAIHVIKKLGGSLADSYLDEGFLLDKKIGVNQPKRIENAKILIANTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYPEQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMIGEDKLIHFSGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDPRTVYGGGCSEMLMAHAVAKLASKTPGKEAVAMESFAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGRTTTGLDMKEGTIGDMAVLGITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRKRVPDHHPC", "length": 535 }, "evidence": [ { "id": "Q9W392", "url": "https://omabrowser.org/oma/group/Q9W392/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P39076-1", "protein_name": "T-complex protein 1 subunit beta", "gene_name": "CCT2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSVQIFGDQVTEERAENARLSAFVGAIAVGDLVKSTLGPKGMDKLLQSASSNTCMVTNDGATILKSIPLDNPAAKVLVNISKVQDDEVGDGTTSVTVLSAELLREAEKLIDQSKIHPQTIIEGYRLASAAALDALTKAAVDNSHDKTMFREDLIHIAKTTLSSKILSQDKDHFAELATNAILRLKGSTNLEHIQIIKILGGKLSDSFLDEGFILAKKFGNNQPKRIENAKILIANTTLDTDKVKIFGTKFKVDSTAKLAQLEKAEREKMKNKIAKISKFGINTFINRQLIYDYPEQLFTDLGINSIEHADFEGVERLALVTGGEVVSTFDEPSKCKLGECDVIEEIMLGEQPFLKFSGCKAGEACTIVLRGATDQTLDEAERSLHDALSVLSQTTKETRTVLGGGCAEMVMSKAVDTEAQNIDGKKSLAVEAFARALRQLPTILADNAGFDSSELVSKLRSSIYNGISTSGLDLNNGTIADMRQLGIVESYKLKRAVVSSASEAAEVLLRVDNIIRARPRTANRQHM", "length": 527 }, "evidence": [ { "id": "RGD:1359143", "url": "https://alliancegenome.org/gene/RGD:1359143#orthology", "database": "AGR" }, { "id": "MGI:107186", "url": "https://alliancegenome.org/gene/MGI:107186#orthology", "database": "AGR" }, { "id": "HGNC:1615", "url": "https://alliancegenome.org/gene/HGNC:1615#orthology", "database": "AGR" }, { "id": "FB:FBgn0030086", "url": "https://alliancegenome.org/gene/FB:FBgn0030086#orthology", "database": "AGR" }, { "id": "SGD:S000001404", "url": "https://alliancegenome.org/gene/SGD:S000001404#orthology", "database": "AGR" }, { "id": "Q9W392", "url": "https://omabrowser.org/oma/group/Q9W392/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P78371-1", "protein_name": "T-complex protein 1 subunit beta", "gene_name": "CCT2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASLSLAPVNIFKAGADEERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDASLMVTNDGATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQTIIAGWREATKAAREALLSSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFTKLAVEAVLRLKGSGNLEAIHIIKKLGGSLADSYLDEGFLLDKKIGVNQPKRIENAKILIANTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYPEQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMIGEDKLIHFSGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCSEMLMAHAVTQLANRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGNTTAGLDMREGTIGDMAILGITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRKRVPDHHPC", "length": 535 }, "evidence": [ { "id": "RGD:1359143", "url": "https://alliancegenome.org/gene/RGD:1359143#orthology", "database": "AGR" }, { "id": "MGI:107186", "url": "https://alliancegenome.org/gene/MGI:107186#orthology", "database": "AGR" }, { "id": "HGNC:1615", "url": "https://alliancegenome.org/gene/HGNC:1615#orthology", "database": "AGR" }, { "id": "FB:FBgn0030086", "url": "https://alliancegenome.org/gene/FB:FBgn0030086#orthology", "database": "AGR" }, { "id": "SGD:S000001404", "url": "https://alliancegenome.org/gene/SGD:S000001404#orthology", "database": "AGR" }, { "id": "Q9W392", "url": "https://omabrowser.org/oma/group/Q9W392/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P80314-1", "protein_name": "T-complex protein 1 subunit beta", "gene_name": "Cct2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASLSLAPVNIFKAGADEERAETARLSSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDAALMVTNDGATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQTIISGWREATKAAREALLSSAVDHGSDEARFWQDLMNIAGTTLSSKLLTHHKDHFTKLAVEAVLRLKGSGNLEAIHVIKKLGGSLADSYLDEGFLLDKKIGVNQPKRIENAKILIANTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYPEQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMIGEDKLIHFSGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDPRTVYGGGCSEMLMAHAVTQLANRTPGKEAVAMESFAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGHITAGLDMKEGTIGDMAVLGITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRKRVPDHHPC", "length": 535 }, "evidence": [ { "id": "RGD:1359143", "url": "https://alliancegenome.org/gene/RGD:1359143#orthology", "database": "AGR" }, { "id": "MGI:107186", "url": "https://alliancegenome.org/gene/MGI:107186#orthology", "database": "AGR" }, { "id": "HGNC:1615", "url": "https://alliancegenome.org/gene/HGNC:1615#orthology", "database": "AGR" }, { "id": "FB:FBgn0030086", "url": "https://alliancegenome.org/gene/FB:FBgn0030086#orthology", "database": "AGR" }, { "id": "SGD:S000001404", "url": "https://alliancegenome.org/gene/SGD:S000001404#orthology", "database": "AGR" }, { "id": "Q9W392", "url": "https://omabrowser.org/oma/group/Q9W392/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3ZBH0-1", "protein_name": "T-complex protein 1 subunit beta", "gene_name": "CCT2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MASLSLAPVNIFKAGADEERAETARLSSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDASLMVTNDGATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQTIIAGWREATKAARQALLNSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFTKLAVEAVLRLKGSGNLEAIHVIKKLGGSLADSYLDEGFLLDKKIGVNQPKRIENAKILIANTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYPEQLFGAAGVMAIEHADFVGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMIGEDKLIHFSGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCSEMLMAHAVTQLASRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGKTTAGLDMKEGTIGDMSVLGITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRKRVPDHHPC", "length": 535 }, "evidence": [ { "id": "Q9W392", "url": "https://omabrowser.org/oma/group/Q9W392/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54ES9-1", "protein_name": "T-complex protein 1 subunit beta", "gene_name": "cct2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSSQLAPIPILNQNASEERGEIARLSSFVGAIAITDLVKTTLGPKGMDKILISASNPNELIITNDGATILTKIYIDNPAAKILVDISRTQDDEVGDGTTSVCVLAGELLREGERLVQQKVHPQTIISGWRLALETARAALQSSTQDHSSDKVKFREDLLNIARTTLSSKILHTEKDHFANMVVDAVLRLNGNTNLDNIHIIKKSGGSLRESYLDEGFILEKKIGVGCPKRLENPKILIANTAMDTDKIKIFGGKVVVDSMTELAKMEDAEKEKMLNKCKKIVDHGINCFVNRQLVYNLPEQYFAEHGVMSIEHADFDGIERLALVTGAEIVSTFDHPELVKIGTCKLIEEVMIGEDKVIRFSGIPSGEACTIVLRGATSHILEEAERSIHDALCVLAVTVAETRTVLGAGCSEMIMSKAVDELAAITPGKKAMAIESFAKALRQIPTIIANNAGYDSSELVSQLKAAHHQGDKKAGLNMRDGCIGNAEELGVIESFKVKQQVLVSAHEAAEMIMRVDDILRAAPRQRSNLQH", "length": 532 }, "evidence": [ { "id": "Q9W392", "url": "https://omabrowser.org/oma/group/Q9W392/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5XIM9-1", "protein_name": "T-complex protein 1 subunit beta", "gene_name": "Cct2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASLSLAPVNIFKAGADEERAETARLSSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDASLMVTNDGATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQTIIAGWREATKAAREALLSSAVDHGSDEVKFWQDLMNIAGTTLSSKLLTHHKDHFTKLAVEAVLRLKGSGNLEAIHVIKKLGGSLADSYLDEGFLLDKKIGVNQPKRIENAKILIANTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYPEQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMIGEDKLIHFSGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDPRTVYGGGCSEMLMAHAVTMLASRTPGKEAVAMESFAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGRITAGLDMKEGSIGDMAVLGITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRKRVPDHHPC", "length": 535 }, "evidence": [ { "id": "RGD:1359143", "url": "https://alliancegenome.org/gene/RGD:1359143#orthology", "database": "AGR" }, { "id": "MGI:107186", "url": "https://alliancegenome.org/gene/MGI:107186#orthology", "database": "AGR" }, { "id": "HGNC:1615", "url": "https://alliancegenome.org/gene/HGNC:1615#orthology", "database": "AGR" }, { "id": "FB:FBgn0030086", "url": "https://alliancegenome.org/gene/FB:FBgn0030086#orthology", "database": "AGR" }, { "id": "SGD:S000001404", "url": "https://alliancegenome.org/gene/SGD:S000001404#orthology", "database": "AGR" }, { "id": "Q9W392", "url": "https://omabrowser.org/oma/group/Q9W392/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q940P8-1", "protein_name": "T-complex protein 1 subunit beta", "gene_name": "CCT2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MPIDKIFKDDASEEKGERARMASFVGAMAISDLVKSTLGPKGMDKILQSTGRGHAVTVTNDGATILKSLHIDNPAAKVLVDISKVQDDEVGDGTTSVVVLAGELLREAEKLVASKIHPMTIIAGYRMASECARNALLKRVIDNKDNAEKFRSDLLKIAMTTLCSKILSQDKEHFAEMAVDAVFRLKGSTNLEAIQIIKKPGGSLKDSFLDEGFILDKKIGIGQPKRIENANILVANTAMDTDKVKIYGARVRVDSMTKVAEIEGAEKEKMKDKVKKIIGHGINCFVNRQLIYNFPEELFADAGILAIEHADFEGIERLGLVTGGEIASTFDNPESVKLGHCKLIEEIMIGEDKLIHFSGCEMGQACSIVLRGASHHVLDEAERSLHDALCVLSQTVNDTRVLLGGGWPEMVMAKEVDELARKTAGKKSHAIEAFSRALVAIPTTIADNAGLDSAELVAQLRAEHHTEGCNAGIDVITGAVGDMEERGIYEAFKVKQAVLLSATEASEMILRVDEIITCAPRRREDRM", "length": 527 }, "evidence": [ { "id": "Q9W392", "url": "https://omabrowser.org/oma/group/Q9W392/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9W392", "url": "https://www.uniprot.org/uniprotkb/Q9W392" } ], "pmid": "" }, { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "Q9W392", "url": "https://www.uniprot.org/uniprotkb/Q9W392" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "Q9W392", "url": "https://www.uniprot.org/uniprotkb/Q9W392" } ], "pmid": "" }, { "name": "ATP-dependent protein folding chaperone", "id": "GO:0140662", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140662", "evidence": [ { "database": "UniProtKB", "id": "Q9W392", "url": "https://www.uniprot.org/uniprotkb/Q9W392" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9W392", "url": "https://www.uniprot.org/uniprotkb/Q9W392" } ], "pmid": "" }, { "name": "chaperonin-containing T-complex", "id": "GO:0005832", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005832", "evidence": [ { "database": "UniProtKB", "id": "Q9W392", "url": "https://www.uniprot.org/uniprotkb/Q9W392" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "Q9W392", "url": "https://www.uniprot.org/uniprotkb/Q9W392" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 148, "end_pos": 150, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 148, "end_pos": 150 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9W397-1", "uniprot_ac": "Q9W397", "uniprot_id": "Q9W397_DROME", "mass": { "chemical_mass": 70104.0, "monoisotopic_mass": 70104.0 }, "refseq": { "ac": "NP_572520", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572520" }, "gene_names": [ { "name": "Dmel\\CG7246", "type": "recommended", "evidence": [ { "id": "Q9W397", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W397" } ] }, { "name": "CG7246", "type": "synonym", "evidence": [ { "id": "NP_572520", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572520" }, { "id": "Q9W397", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W397" } ] }, { "name": "Dmel\\CG7246", "type": "synonym", "evidence": [ { "id": "NP_572520", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572520" } ] }, { "name": "Dmel_CG7246", "type": "synonym", "evidence": [ { "id": "Q9W397", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W397" } ] }, { "name": "UTP6", "type": "synonym", "evidence": [ { "id": "NP_572520", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572520" }, { "id": "Q9W397", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W397" } ] }, { "name": "dUTP6", "type": "synonym", "evidence": [ { "id": "NP_572520", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572520" }, { "id": "Q9W397", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W397" } ] } ], "protein_names": [ { "name": "U3 small nucleolar RNA-associated protein 6 homolog", "type": "recommended", "evidence": [ { "id": "Q9W397", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W397/entry#names_and_taxonomy" } ] }, { "name": "CG7246-PA", "type": "synonym", "evidence": [ { "id": "NP_572520", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572520" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_572520", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572520" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W397", "url": "https://www.uniprot.org/uniprotkb/Q9W397" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG7246", "url": "https://www.uniprot.org/uniprotkb/Q9W397", "locus": { "chromosome": "X", "start_pos": 9078823, "end_pos": 9081057, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0030081", "url": "https://www.ensemblgenomes.org/id/FBgn0030081" } ] } } ], "crossref": [ { "id": "FB:FBgn0030081", "url": "https://alliancegenome.org/gene/FB:FBgn0030081", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0030081", "url": "https://bgee.org/?page=gene&gene_id=FBgn0030081", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0030081", "url": "https://flybase.org/reports/FBgn0030081", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "31833", "url": "https://www.ncbi.nlm.nih.gov/gene/31833", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003107", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003107", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013949", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013949", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG7246", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG7246", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CKQWNAK", "url": "https://omabrowser.org/oma/group/CKQWNAK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W397", "url": "https://www.orthodb.org/?gene=Q9W397", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23271", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23271", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23271:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23271:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08640", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08640", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24892", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24892", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6791226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_572520", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572520", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W397", "url": "https://www.uniprot.org/uniprotkb/Q9W397", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W397-1", "url": "https://www.uniprot.org/uniprotkb/Q9W397-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEFIAEMQERLLPEYEQMKNYSVFTADQVREIVSRRERLFLKINKSHQSITDYLDFILYEKHMHMTIVDKEKKMHVKLTGLKASIATRIMRLYREALAKFNHDRRLWSNWIKFSRKSNPVEVAGIYEKMLLYHGDSPDLWVDAALWLYEFNRLNIDRVKDILLRGLQRHPDSEALNKCFFDIMLKEAALASNERNLAENTLSEQDIKLERVEAVYRNSMANITQLDYFVKLLESCEDHQELTGKLQRMIIDDMQEKFPREPGLWDLLAQRELRGFHLGDLEEEDLDTSDEEPASKKSRSVNGRSLKRRIQLCVTVYKSAVEELQTTEMWNMYLDAMLALNSDGKTERILKQQCLADALQAGHRSQLMGVKHYATLRKMLCTAPSGREAAVTILTEALKNDSSVEMHELLLATHIQSDSEPLIYELFNKIQKSMGSEALPLWRSVILYYRTRQDSLGARRLDEIYGLACKAAWPEFGELRSDYLRYLWQERSVEEARKEYAKLAILPPMSLALHRQMVQLESSAAACDQASLKYWRMCYDFMACYFGKTQPRVWVEYLAFERDHGEAKNISLLTQRALSTLEPQYVAAFEAERALAYVGASI", "length": 602, "header": "tr|Q9W397-1|Q9W397_DROME Isoform 1 of U3 small nucleolar RNA-associated protein 6 homolog OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG7246 PE=3 SV=1 CANONICAL=Q9W397-1" }, "isoforms": [ { "isoform_ac": "Q9W397-1", "url": "https://www.uniprot.org/uniprotkb/Q9W397/entry#Q9W397-1", "sequence": { "sequence": "MAEFIAEMQERLLPEYEQMKNYSVFTADQVREIVSRRERLFLKINKSHQSITDYLDFILYEKHMHMTIVDKEKKMHVKLTGLKASIATRIMRLYREALAKFNHDRRLWSNWIKFSRKSNPVEVAGIYEKMLLYHGDSPDLWVDAALWLYEFNRLNIDRVKDILLRGLQRHPDSEALNKCFFDIMLKEAALASNERNLAENTLSEQDIKLERVEAVYRNSMANITQLDYFVKLLESCEDHQELTGKLQRMIIDDMQEKFPREPGLWDLLAQRELRGFHLGDLEEEDLDTSDEEPASKKSRSVNGRSLKRRIQLCVTVYKSAVEELQTTEMWNMYLDAMLALNSDGKTERILKQQCLADALQAGHRSQLMGVKHYATLRKMLCTAPSGREAAVTILTEALKNDSSVEMHELLLATHIQSDSEPLIYELFNKIQKSMGSEALPLWRSVILYYRTRQDSLGARRLDEIYGLACKAAWPEFGELRSDYLRYLWQERSVEEARKEYAKLAILPPMSLALHRQMVQLESSAAACDQASLKYWRMCYDFMACYFGKTQPRVWVEYLAFERDHGEAKNISLLTQRALSTLEPQYVAAFEAERALAYVGASI", "length": 602, "header": "tr|Q9W397-1|Q9W397_DROME Isoform 1 of U3 small nucleolar RNA-associated protein 6 homolog OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG7246 PE=3 SV=1 CANONICAL=Q9W397-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W397", "url": "https://www.uniprot.org/uniprotkb/Q9W397" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W397", "url": "https://www.uniprot.org/uniprotkb/Q9W397" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W397", "url": "https://www.uniprot.org/uniprotkb/Q9W397" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W397", "url": "https://www.uniprot.org/uniprotkb/Q9W397" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W397", "url": "https://www.uniprot.org/uniprotkb/Q9W397" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W397", "url": "https://www.uniprot.org/uniprotkb/Q9W397" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W397", "url": "https://www.uniprot.org/uniprotkb/Q9W397" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W397", "url": "https://www.uniprot.org/uniprotkb/Q9W397" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W397", "url": "https://www.uniprot.org/uniprotkb/Q9W397" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W397", "url": "https://www.uniprot.org/uniprotkb/Q9W397" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W397", "url": "https://www.uniprot.org/uniprotkb/Q9W397" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG7246", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG7246", "resource": "KEGG Pathway" }, { "id": "R-DME-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287ADC2-1", "protein_name": "U3 small nucleolar RNA-associated protein 6 homolog", "gene_name": "UTP6", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAEIIQERIEDRLPELEQLERIGLFSRAEIKAIIKKASDLEYKIQRRTLFKEDFINYVQYEINLLELIQRRRAHIGYSFKKDEIENSIVHRVQGVFRRASAKWKDDVQLWLSYVVFCKKWATKAQLSKVFSAMLAIHSNKPALWIMAAKWEMEDRLSSESARQLFLRALRFHPECPKLYQEYFRMELMHAEKLRKEKQEFETAKMDVENLEYSEEILKGELARIIYKNSVSIIKGAEFHVSLLSIAQLFDFAKDLQREIYDDLQALHTDDPLTWDYVARRELEMESQPGDEPPTTKQAKVAEATRREERCCAVYEEAVKTLPTEAMWKCYLNFCMERFTKKTNSQLLREKRLERTMVAFRKAHELRLLPEVQYKQWSELLLQHNLFKEALEVAGAGTELFQDSVMMWQVKLQVLIASESPDVAMVFEEAFVRLKPQICLPLWISWAEWSEGAKSQEDTEAIFKKAVLAVMGADSVTLKDKYLDWAYRSSGYKKARAVFKSLQESRPFSVDFFRKMIQFEKEQESCKMANLREYYERALREFGSVDSDLWMDYIKEELDHPLGRPENCGQIYWRAMKMLQGEAAELFVAKHAMHQAGHL", "length": 598 }, "evidence": [ { "id": "Q9W397", "url": "https://omabrowser.org/oma/group/Q9W397/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1M805-1", "protein_name": "UTP6 small subunit processome component", "gene_name": "Utp6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEIIQERIEDRIPELEQLERIGLFSRAEIKAIIKKASDLEYKIHRRNLHKEDFISYVQYEINLLELIQRRRARIKYSFKKDEIEYSMVHRVQGIFGRASAKWKDDVQLWLSYIVFCKKWGTKAHLSKIFSNMLAIHSNKPALWIMAAKWEMEDRLSSESARQLFLRALRFHPECPKLYQEYFRMELMHAEKLRKEKQEFEKAAMDMGDFDHPEEILKGELARIVYKSAVSKIKGAEFHVSLLAISQLFDFAKDLQKEIYDDLQALHTDDPLTWDYVARRELEIESQPGEEQPVSKQAKAVEMGRREERCCAVYEEAVRTLPTEAMWKCYITFCLERFSKKTSSVSLRGQRLERTMRAFRKAHELKLLSEVQYKQWIDLLLRQDLFKEALQVAEAGTELFKDSVTMWQTKLLVLIDSKSPDVGVHFEEAFAHLKPQVCLSLWISWAEWSESVESQEDTEAIFKRALLAVTGANSITLKEKYLDWAYRSGGYKKARAVFKSLQESRPFSVEFFRKMMQFEKEQDSSKMVNLREYYERALREFGSTDSDLWLDYMNEELNHPFGKPENCGQIYWRAMRMLQGQSASMFVAKHAMHQAGH", "length": 597 }, "evidence": [ { "id": "RGD:1311017", "url": "https://alliancegenome.org/gene/RGD:1311017#orthology", "database": "AGR" }, { "id": "MGI:2445193", "url": "https://alliancegenome.org/gene/MGI:2445193#orthology", "database": "AGR" }, { "id": "HGNC:18279", "url": "https://alliancegenome.org/gene/HGNC:18279#orthology", "database": "AGR" }, { "id": "FB:FBgn0030081", "url": "https://alliancegenome.org/gene/FB:FBgn0030081#orthology", "database": "AGR" }, { "id": "SGD:S000002857", "url": "https://alliancegenome.org/gene/SGD:S000002857#orthology", "database": "AGR" }, { "id": "Q9W397", "url": "https://omabrowser.org/oma/group/Q9W397/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q02354-1", "protein_name": "U3 small nucleolar RNA-associated protein 6", "gene_name": "UTP6", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSKTRYYLEQCIPEMDDLVEKGLFTKNEVSLIMKKRTDFEHRLNSRGSSINDYIKYINYESNVNKLRAKRCKRILQVKKTNSLSDWSIQQRIGFIYQRGTNKFPQDLKFWAMYLNYMKARGNQTSYKKIHNIYNQLLKLHPTNVDIWISCAKYEYEVHANFKSCRNIFQNGLRFNPDVPKLWYEYVKFELNFITKLINRRKVMGLINEREQELDMQNEQKNNQAPDEEKSHLQVPSTGDSMKDKLNELPEADISVLGNAETNPALRGDIALTIFDVCMKTLGKHYINKHKGYYAISDSKMNIELNKETLNYLFSESLRYIKLFDEFLDLERDYLINHVLQFWKNDMYDLSLRKDLPELYLKTVMIDITLNIRYMPVEKLDIDQLQLSVKKYFAYISKLDSASVKSLKNEYRSYLQDNYLKKMNAEDDPRYKILDLIISKL", "length": 440 }, "evidence": [ { "id": "RGD:1311017", "url": "https://alliancegenome.org/gene/RGD:1311017#orthology", "database": "AGR" }, { "id": "MGI:2445193", "url": "https://alliancegenome.org/gene/MGI:2445193#orthology", "database": "AGR" }, { "id": "HGNC:18279", "url": "https://alliancegenome.org/gene/HGNC:18279#orthology", "database": "AGR" }, { "id": "FB:FBgn0030081", "url": "https://alliancegenome.org/gene/FB:FBgn0030081#orthology", "database": "AGR" }, { "id": "SGD:S000002857", "url": "https://alliancegenome.org/gene/SGD:S000002857#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54WN5-1", "protein_name": "U3 small nucleolar RNA-associated protein 6 homolog", "gene_name": "utp6", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDRVNFSIDQLLEETSKLVSLGIISKQECKDIMKKREYHEIKIFNRNSHKSDFLTYIKYELELDRLFHKRGKAKNIEFDYRLRSALRHAIILFGSATKKFPKDEALWINALNIRMKRASKEGTGRLFSIALSNLPRSAKLWKLAATFEFEVNKNIQNARNLIQAGIQFNKTDKSLWHYFFLMELTYISLLFSDITFIDKKIEEEEEEAIKLNLDSLRKSEKIEKDEFITFGKEILSADKLKQSSLIRGQIAQIVFRKAIKSSIGQDFDFRKHFYKIASKFLDIGKDSENPMGAGELLQKEILESLVTDFPNDDKTYIFLASIEQSKSSEPSLLKRLNNSTKILNQGLTIIKSESYLFNYIHFIRQIIVDIKLKENKLIENITDILLKAYKYSIDNNILKESGYQYYIELLLELGKTNDAIKVSEESVKLFKNSNQLWNQRINLLIKNEMVVKLFDNLSNNNEYNNIDKCFEMAVKNCTSSTTSTTSSTSTSSSSNLFIEYFKYQVVFKFDKDYKKIVDLFEKLLKQLDEFYQKCILYEEERIEKNINDIRSLYEKCLSIKEISSKDVDVWLNYRNFELKSAGDIERANTIATRGKKSLADPLPLLSQLQ", "length": 609 }, "evidence": [ { "id": "Q9W397", "url": "https://omabrowser.org/oma/group/Q9W397/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8VCY6-1", "protein_name": "U3 small nucleolar RNA-associated protein 6 homolog", "gene_name": "Utp6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEIIQERIEDRIPELEQLERIGLFSHAEIKAIIKKASDLEYKIHRRTLLKEDFINYVQYEINLLELIQRRRARIKYSFKKDEIEYSMVHRVQGVFGRASAKWKDDVQLWLSYIVFCKKWGTKTHLSKIFSAMLAIHSNKPALWIMAAKWEMEDRLSSESARQLFLRALRFHPECPKLYQEYFRMELMHAEKLRKEKQEFEKAAMDMGDFDHPEEILKGELARIIYKNSISKIKGAEFHVSLLAIAQLFDFAKDLQKEIYDDLQALHTDDPLTWDYVARRELEIESQPGEEQPVSKQAKAVEMGRREERCCAVYEEAVKALPTEAMWKCYITFCLERFSKKTSSVPLRGQRLERTMLAFRKAHELKLLSEVQYKQWIDLLLRQDLFKEALQVAEAGTELFKDSVTMWQTKLQVLIDSKSPDVEMRFEEAFAHLKPQVCLPLWISWAEWSESAKSQEDTEAIFKKAIIAVTGASSVTLKEKYLDWAYRSGGYKKARAVFKSLQESRPFSVEFFRKMMQFEKEQEPCKMVNLREYYERALREFGTSDSDLWMDYIKEELNHPFGKPENCGQIYWRAMKMLQGQSAELFVAKHAMHQAGH", "length": 597 }, "evidence": [ { "id": "RGD:1311017", "url": "https://alliancegenome.org/gene/RGD:1311017#orthology", "database": "AGR" }, { "id": "MGI:2445193", "url": "https://alliancegenome.org/gene/MGI:2445193#orthology", "database": "AGR" }, { "id": "HGNC:18279", "url": "https://alliancegenome.org/gene/HGNC:18279#orthology", "database": "AGR" }, { "id": "FB:FBgn0030081", "url": "https://alliancegenome.org/gene/FB:FBgn0030081#orthology", "database": "AGR" }, { "id": "SGD:S000002857", "url": "https://alliancegenome.org/gene/SGD:S000002857#orthology", "database": "AGR" }, { "id": "Q9W397", "url": "https://omabrowser.org/oma/group/Q9W397/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9M0I7-1", "protein_name": "U3 small nucleolar RNA-associated-like protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MADVVQYRLERMVDELDDLERREIFTRAEIAEIVKQRRKFEYRLKRPSPLKEDFIAYIDYEVKLDELRQLRRKSVARVTKKRKKKSVSDFAGVARIVEIYRLATMRYKGDINLWFRYLEFCKQKRHGRMKKALAQAIRFHPKVAGVWIYAASWEFDRNLNVTAARALMLNGLRVCSNSEDLWVEYLRMELTFLNKLKARKVALGEDKGSLVRDTKTVEDEQWKDENKELFMSLDEKEGNEKEENDEDSIVEDVEDVTEKVDFLKEKGSNVLQTIYSGAVEAIPSSFDLRKRFLEILEATDLAHSDEMRNTILSDLKRDFCNEPEYWNWLARHEMSGCISNEAGLEFANPQMQKAIQVFEEGLQTVTSSSMFEIYINFLMEAIVQSNGDENEISSLSNPIISHIINVYQKADETGCLTEELADEYVSLYLKLEKTHEAQKLAEKLCSEKFAGSAKLWLSRVSIEIRSLSENSSPSKADFQTVFELLSNALRKVPISESESLWLMAFNFFAHQRTYLDKLVEMSILSATKSHGSDHVFSLASTVVKFVLETKGAHSARKIYKRFLALPGPSLVLYKGCIEIETNLISVGDKDGLSNARKLYDSAVASYGQDVELWKNYYSLETKLGTSETANGVYWRARKTLNESADFIV", "length": 648 }, "evidence": [ { "id": "Q9W397", "url": "https://omabrowser.org/oma/group/Q9W397/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9NYH9-1", "protein_name": "U3 small nucleolar RNA-associated protein 6 homolog", "gene_name": "UTP6", "tax_id": 9606, "organism": 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"database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22803", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22803", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00059", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00059", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001259341", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259341", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W3D8", "url": "https://www.uniprot.org/uniprotkb/Q9W3D8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W3D8-1", "url": "https://www.uniprot.org/uniprotkb/Q9W3D8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYRTETLLLILTSVGIPSLAYLPDVNIFTNYRTEVYNGIPSEIDTTPFVRIGDNYYYIEPMNKVNWFQAAGACRMMNAHLASIEDKPEMEALIKYMKAKGFKNNDYFWISGNDLGTEGAFYWMSNGRPMTYAPWNGPKQMPDNYGGNENCVHMFATREMINDANCKIQMLYVCEATEPKTFKFTYIKW", "length": 188, "header": "tr|Q9W3D8-1|Q9W3D8_DROME Isoform 1 of C-type lectin domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG12111 PE=4 SV=1 CANONICAL=Q9W3D8-1" }, "isoforms": [ { "isoform_ac": "Q9W3D8-1", "url": "https://www.uniprot.org/uniprotkb/Q9W3D8/entry#Q9W3D8-1", "sequence": { "sequence": "MYRTETLLLILTSVGIPSLAYLPDVNIFTNYRTEVYNGIPSEIDTTPFVRIGDNYYYIEPMNKVNWFQAAGACRMMNAHLASIEDKPEMEALIKYMKAKGFKNNDYFWISGNDLGTEGAFYWMSNGRPMTYAPWNGPKQMPDNYGGNENCVHMFATREMINDANCKIQMLYVCEATEPKTFKFTYIKW", "length": 188, "header": "tr|Q9W3D8-1|Q9W3D8_DROME Isoform 1 of C-type lectin domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG12111 PE=4 SV=1 CANONICAL=Q9W3D8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W3D8", "url": "https://www.uniprot.org/uniprotkb/Q9W3D8" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W3D8", "url": "https://www.uniprot.org/uniprotkb/Q9W3D8" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3D8", "url": "https://www.uniprot.org/uniprotkb/Q9W3D8" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3D8", "url": "https://www.uniprot.org/uniprotkb/Q9W3D8" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W3D8", "url": "https://www.uniprot.org/uniprotkb/Q9W3D8" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W3D8", "url": "https://www.uniprot.org/uniprotkb/Q9W3D8" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W3D8", "url": "https://www.uniprot.org/uniprotkb/Q9W3D8" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3D8", "url": "https://www.uniprot.org/uniprotkb/Q9W3D8" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3D8", "url": "https://www.uniprot.org/uniprotkb/Q9W3D8" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W3D8", "url": "https://www.uniprot.org/uniprotkb/Q9W3D8" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W3D8", "url": "https://www.uniprot.org/uniprotkb/Q9W3D8" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG12111", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG12111", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1RLL2-1", "protein_name": "Uncharacterized protein dcsignlg", "gene_name": "dcsignlg", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEAVYENVECRDIKNSTGPQSQNHNRDEENDRKRRRWKCVVLVIMGLICALLLLFITLQNISITAERDLFKTYKNTVEELNHTISSLQHDNTDLETDKQQLEDKYNSLSLKKQQLETKYNSLSLGKQQLENRVTSLSAELKEARSKSGWFFMSTEAMSWSESRQFCRDRGADLVIIKSEEKQRFISSLVKEDTWIGLSVTETGGNKWKWVDNSPLNQGFWAKGEPNNYQGAKEDCVEVRISQGTPNNWNDRRCSDSRKAVCEK", "length": 263 }, "evidence": [ { "id": "HGNC:25357", "url": "https://alliancegenome.org/gene/HGNC:25357#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z340-1", "protein_name": "Uncharacterized protein si:ch211-133n4.7", "gene_name": "si:ch211-133n4.7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDSVYENSRIVLSTVASNENSRNEGNHSYEQESEREVNTAKWNKLLLTVFAVSLVFALGGLCVVSILYVRALTQQSAQTNTKIMKRQLEELTANCSRVKDDLYIKDSMMKDLTANYSRVKDDLHIKDSMVKELTANNSRIKEQQSFYKAFRASNMTAFQGKLYFFSSDKLTWSSSRAFCVSRGTDLVTITSRSEQAFLQSKMNEWTWIGLSDLETEGRWVWVNNQTLNDTGVEFWYKRQSGKSEPDNWTKDDPSGEHCAIVKYALNYLKSWFDVSCEHTYKFICEKKI", "length": 288 }, "evidence": [ { "id": "HGNC:25357", "url": "https://alliancegenome.org/gene/HGNC:25357#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PGK7-1", "protein_name": "Immune-related, lectin-like receptor 3 isoform X1", "gene_name": "illr3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGSVYENSVFAFSTGNSDENDSQYKGHFSNYRESKREVNTAKWTKVLLIVFAVSLVFALGGLCAVRIQYVSVSAQLSAQETNGTIMSRQLDKLTANFTTVRDHLHINELLMKELTANYSRVKEQLSISEETVRKLSRFNQSSGCAICAIHWTHSGEKCYYFSTVKMNWTQSRDHCVTKGGHLVIITSQAEQEFLTSNVKETHWIGLNDLDTEGRWLWVDNQPLSQTEEFWMKRENGVSEPDNWTKQHVDGEDCASLGHPDGETDFWTDAYCFEEKRFVCEAAAAV", "length": 285 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050311-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050311-4#orthology", "database": "AGR" }, { "id": "FB:FBgn0030050", "url": "https://alliancegenome.org/gene/FB:FBgn0030050#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TFP3-1", "protein_name": "Uncharacterized protein zmp:0000000937 isoform X1", "gene_name": "zmp:0000000937", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTSGIEMAQPIYGNILVNYDPTPKMDRCSLRNETASDSGKKRSSRAAPVCLVLLCLLLLTAVIVLSVFIYTNNTNFAEERRQLITNIANITEDRDKLLTDIINLTKIKDKVLINITNLEEDRDELLNKITTFTKARNEILKKNANLLKDKDQLIKQLQVFGQEAYYQSSFYYLSSERKSWTESRRDCKDRGADLIIINNKQEQDFIMKITSNNEFWIGLTDSDKEGIWKWVDGSNLTSRFWASSGSITEPNGRKTENCAVTHLKKHPELIGWLDVACDGAYQWICEKNILPVTS", "length": 294 }, "evidence": [ { "id": "HGNC:25357", "url": "https://alliancegenome.org/gene/HGNC:25357#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "B7Z0K3-1", "protein_name": "C-type lectin domain-containing protein", "gene_name": "Dmel\\CG14866", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPPAGQQLRLTALVYLALGIALLCNGSDGETRQKYANESLADADDPSPVWSQFLEDYVLSQGSSSSGSQRKSKDLPYMGADMGINGPLSYHSSAYKRPGNNIYITRRIGEAVELEPHLRKPVESQSPIVNPQFRPMTNQMLHQQHQQMQQQQQQQQLQQRQQPGFLQQLFGIGGSGGGGGSGTQQQQHVRPVPLQQQQVQQIAQQHPQQQHLVGGQPTTFRAVSENDLYLLGAIEKLVYRVDYLESRVRRSEQLIYYLMAGNNQKEVKDPCPANFTRISDNCYYINSQQQVNWKTANSACKGLNSHLAEFEKVSENEEIMAYLLNQPTHRGRDYWLGGLNPGLLWIWSNSAKPVNPNMNLTSIAMAQKGENSTAANLVDSSEQAAEEATGEDVLNNTVQIEGKGRCLRLSYNAGKHSYVYYGQECTSRHYYICEHEDKTLDNKIKKITRELKLFE", "length": 455 }, "evidence": [ { "id": "RGD:1565913", "url": "https://alliancegenome.org/gene/RGD:1565913#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "D3ZBX0-1", "protein_name": "C-type lectin domain family 4 member K", "gene_name": "Cd207", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEVEMKETEVPDAHFTVDKQNISLWPREPPPKQDLTPVLRKPHCICAAFICLALVLVTSIVLQAVFYPRLMGKILDVKSDAQMLRGRVDNISTLGSDLKRERGRVDDAEVQMRIVNTSLGRVRSKILSLEASMKIVSNQLQVLTMNWGEVDNLNAKIPELQKDLDKASALNTKVQGLQNSLENINKLLKEQSDILEMMSRGWKYFMGNFYYFSRTPKTWYSAEQYCISRKAHLTSVSSESEHEFLYKVADGIPHWIGLTKAGSEGDWYWVDQTSFNKEQSRRFWIPGEPNNVRNNEHCANIRVSALKCWNDSPCDNVYSFICKMPYIRMIT", "length": 332 }, "evidence": [ { "id": "RGD:1565913", "url": "https://alliancegenome.org/gene/RGD:1565913#orthology", "database": "AGR" }, { "id": "FB:FBgn0030050", "url": "https://alliancegenome.org/gene/FB:FBgn0030050#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZXM6-1", "protein_name": "C-type lectin domain family 6, member A, pseudogene 1", "gene_name": "Clec6a-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVQERHPQRKGVCWTLRLWSTAVISMLLLSTCFIASCMVTYQFTMEKPNRRLSELHTYHSSLTCCSKGTMVSEKLWGCCPNHWKSFGSSCYLISTKENFWSISEQNYIHMGAHLVVINTETEQNFITQQLNESLSYFLGLSDPQGNSKWQWIDNTPFSQNVRFWHPHEPNLPEEWCASIVYWNPSKWGWNDVFCDSKHNSICETKKIYL", "length": 209 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050311-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050311-4#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3V638-1", "protein_name": "Fc epsilon receptor II", "gene_name": "Fcer2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAHSQVERGNSRPLPSVTQYLPNKIHSSWAAGVQIALKANLNGNLEFRMNSQNQGYWEPPRRRCCCARRGTQLVLVGLLTTVMWAGLLALLLLWHWETEKSLKQLGDAAIQNVSHVTKDLQNYQSNQLAQKSQALQMSQNLEELQAEQKQMKSQDSQLSQNLNELQEDLINVKSQNSELSQNLNTLQEDLVNVKSQGLNEKRAASDSLEKLQEEVAKLWIEILMSKGTACNVCPKDWLHFQQKCYYFGEGSKQWIQAKFTCSDLEGRLVSIHSQKEQDFLMQHINKKESWIGLQDLNMEGEFVWPDGSPVGYSNWSPGEPNNGGQGEDCVMMRGSGQWNDAFCRSYLDAWVCEQLATCDLSAPLASVTPTGPTPKNEP", "length": 378 }, "evidence": [ { "id": "MGI:95497", "url": "https://alliancegenome.org/gene/MGI:95497#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P06734-1", "protein_name": "Low affinity immunoglobulin epsilon Fc receptor", "gene_name": "FCER2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEGQYSEIEELPRRRCCRRGTQIVLLGLVTAALWAGLLTLLLLWHWDTTQSLKQLEERAARNVSQVSKNLESHHGDQMAQKSQSTQISQELEELRAEQQRLKSQDLELSWNLNGLQADLSSFKSQELNERNEASDLLERLREEVTKLRMELQVSSGFVCNTCPEKWINFQRKCYYFGKGTKQWVHARYACDDMEGQLVSIHSPEEQDFLTKHASHTGSWIGLRNLDLKGEFIWVDGSHVDYSNWAPGEPTSRSQGEDCVMMRGSGRWNDAFCDRKLGAWVCDRLATCTPPASEGSAESMGPDSRPDPDGRLPTPSAPLHS", "length": 321 }, "evidence": [ { "id": "MGI:95497", "url": "https://alliancegenome.org/gene/MGI:95497#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P10716-1", "protein_name": "C-type lectin domain family 4 member F", "gene_name": "Clec4f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKEAELNRDVAKFCTDNQCVILQPQGLGPKSAAPMAPRTLRHVQAIVALVVVTVFFSLLALFVVVLQPWRQKQNEDHPVKAGLHGGNYSGSDNCSQFVRRAEMQEAIQSLRASGNSSSCHKEIQTLKYQMDNVSSQVQLLGGHLEEANADIQQAKDVLKGTGALASETQALRSSLEVASADIHSLRGDLEKANAMTSQTQGLLKSSTDNTSAELHVLGRGLEEAQSEIQALRGSLQSSNDLGSRTQNFLQHSMDNISAEIQAMRDGMQRAGEEMTSLKKDLETLTAQIQNANGHLEQTDTQIQGLKAQLKSTSSLNSQIEVVNGKLKDSSRELQTLRRDLSDVSALKSNVQMLQSNLQKAKAEVQSLKTGLEATKTLAAKIQGQQSDLEALQKAVAAHTQGQKTQNQVLQLIMQDWKYFNGKFYYFSRDKKSWHEAENFCVSQGAHLASVTSQEEQAFLVQITNAVDHWIGLTDQGTEGNWRWVDGTPFDYVQSRRFWRKGQPDNWRHGNGEREDCVHLQRMWNDMACGTAYNWVCKKSTDWSVARTDQS", "length": 550 }, "evidence": [ { "id": "HGNC:25357", "url": "https://alliancegenome.org/gene/HGNC:25357#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P20693-1", "protein_name": "Low affinity immunoglobulin epsilon Fc receptor", "gene_name": "Fcer2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEENEYSGYWEPPRKRCCCARRGTQLMLVGLLSTAMWAGLLALLLLWHWETEKNLKQLGDTAIQNVSHVTKDLQKFQSNQLAQKSQVVQMSQNLQELQAEQKQMKAQDSRLSQNLTGLQEDLRNAQSQNSKLSQNLNRLQDDLVNIKSLGLNEKRTASDSLEKLQEEVAKLWIEILISKGTACNICPKNWLHFQQKCYYFGKGSKQWIQARFACSDLQGRLVSIHSQKEQDFLMQHINKKDSWIGLQDLNMEGEFVWSDGSPVGYSNWNPGEPNNGGQGEDCVMMRGSGQWNDAFCRSYLDAWVCEQLATCEISAPLASVTPTRPTPKSEP", "length": 331 }, "evidence": [ { "id": "MGI:95497", "url": "https://alliancegenome.org/gene/MGI:95497#orthology", "database": "AGR" }, { "id": "FB:FBgn0030050", "url": "https://alliancegenome.org/gene/FB:FBgn0030050#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P70194-1", "protein_name": "C-type lectin domain family 4 member F", "gene_name": "Clec4f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKEAELNRDMARYCTDNQCVSLQPQGLGPKSAALMAPRTLRHVQVILALMVVTVIFSLLALFVVASQPWRPEWNKEPPSLLLRGSNNSGHDNHSQFVRETEMQVAIQRLRDYEENSSSCHKEVQILKYQMDNVSSLVQLLGSHLEDVNADILQTKDVLKESGALALETQALRSSLEVASADIHSLRGDLEKANAMTSQTRGLLKSSTENTSAELHVLGRGLEEAQSEIQALRGSLQSANDLSSQTQGFLQHSMDNISAQIQTVRDGMERAGEKMNSLKKELETLTAQTQKANGHLEQTDAQIQGLKAELKSTSSLNSRIEVVNGQMKDASRELQTLRRDLSDVSALKSNVQMLQSNLQRAKTEMQTLKADLQATKALTAKIQGEQNRLGALQEAVAAQKQEQKTQNQVLQLIAQNWKYFNGNFYYFSRDKKPWREAEKFCTSQGAHLASVTSQEEQAFLVQTTSSGDHWIGLTDQGTEGIWRWVDGTPFNNAQSKGFWGKNQPDNWRHRNGEREDCVHVRQQWNDMACGSSYPWVCKKSTGWSAARVG", "length": 548 }, "evidence": [ { "id": "HGNC:25357", "url": "https://alliancegenome.org/gene/HGNC:25357#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q59DY5-1", "protein_name": "C-type lectin 37Db", "gene_name": "lectin-37Db", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MMVKLLLLFLVCWSALPLESSPLGNRYNLEIGEKQYYISLAKTNWFEASNHCRQNGGFLLNLESREELELLSPHLHPAYSYWLSINDLGERGVYVSEATGLEAPFLNWSAGEPDNSSGYDRCVELWLSTTSFQMNDLPCYSSVAFICQLN", "length": 150 }, "evidence": [ { "id": "HGNC:25357", "url": "https://alliancegenome.org/gene/HGNC:25357#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q59DY6-1", "protein_name": "C-type lectin 37Da", "gene_name": "lectin-37Da", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLKTLVQLFLVVAGFAPGFGYDKYTTHIQNGNPYNLTVDMTPFIKINESYYVFGQTKVNWYVAYENCRRLQSELVTFETAEEFDAIAAFLNARGDRSEHWTSGNDLGKTGTHYWFSNAQLVTIKRWAPKQPDNAGGREHCIHLGYIYGYSTEFQLNDRPCHNHASSLFKYICEAPKQETVSIVVWK", "length": 186 }, "evidence": [ { "id": "RGD:1565913", "url": "https://alliancegenome.org/gene/RGD:1565913#orthology", "database": "AGR" }, { "id": "HGNC:25357", "url": "https://alliancegenome.org/gene/HGNC:25357#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q67EQ1-1", "protein_name": "C-type lectin domain family 4 member E", "gene_name": "Clec4e", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNSTKSPASHHTERECFKNSQVLSWTMAGASILFLSVCFITRCVVTYHSFQIYGQKKLQPHKTIKELSCYLEASGSVKNCCPLNWKHFQSSCYFFSTTTLSWLSSLKNCSDMGAHLVVINTWEEQEFLFRTKPRKKEFYIGLTDQVVEGQWRWVDDTPFTESLSFWDAGEPNNIVFVEDCATMRDSSNPRKNWNDVSCFFSMPWICEMPEISPLD", "length": 215 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050311-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050311-4#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6EIG7-1", "protein_name": "C-type lectin domain family 6 member A", "gene_name": "CLEC6A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMQEQQPQSTEKRGWLSLRLWSVAGISIALLSACFIVSCVVTYHFTYGETGKRLSELHSYHSSLTCFSEGTKVPAWGCCPASWKSFGSSCYFISSEEKVWSKSEQNCVEMGAHLVVFNTEAEQNFIVQQLNESFSYFLGLSDPQGNNNWQWIDKTPYEKNVRFWHLGEPNHSAEQCASIVFWKPTGWGWNDVICETRRNSICEMNKIYL", "length": 209 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050311-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050311-4#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8IRH8-1", "protein_name": "Triforce, isoform B", "gene_name": "tfc", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MIRPTLIVVLISLASVDSGHNSPVTTIPVAEPISQVPHGFQLGQNNHISSSSNISRSGGGNGRDKRGAQLDPSEIARQNQITQQIFANYLERRLFPNRTANQKIPTIADILPKPKPSPRPRPRGFAASDGGNFKRSGGGAQRNRLAAAASKRQSGYNRKRLREEQEEEEEADDQERDQQPLANQEDFDYDVQESLQSVESEQHDQYYGNIFHRDPSENEVDNDCPNCVDESQYTPNKWTMPLLKLGEKRYYLGIFFKANWFKATQYCRYHGMHLASISSQEENDRLEKHIRDFGLGHEHFWISGTDLADEGNFFWMATGRPITFTNWNAGEPNNFRYENGEEENCLELWNRDGKGLKWNDSPCSFETYFVCEVQPN", "length": 376 }, "evidence": [ { "id": "MGI:95497", "url": "https://alliancegenome.org/gene/MGI:95497#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8N1N0-1", "protein_name": "C-type lectin domain family 4 member F", "gene_name": "CLEC4F", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDGEAVRFCTDNQCVSLHPQEVDSVAMAPAAPKIPRLVQATPAFMAVTLVFSLVTLFVVVQQQTRPVPKPVQAVILGDNITGHLPFEPNNHHHFGREAEMRELIQTFKGHMENSSAWVVEIQMLKCRVDNVNSQLQVLGDHLGNTNADIQMVKGVLKDATTLSLQTQMLRSSLEGTNAEIQRLKEDLEKADALTFQTLNFLKSSLENTSIELHVLSRGLENANSEIQMLNASLETANTQAQLANSSLKNANAEIYVLRGHLDSVNDLRTQNQVLRNSLEGANAEIQGLKENLQNTNALNSQTQAFIKSSFDNTSAEIQFLRGHLERAGDEIHVLKRDLKMVTAQTQKANGRLDQTDTQIQVFKSEMENVNTLNAQIQVLNGHMKNASREIQTLKQGMKNASALTSQTQMLDSNLQKASAEIQRLRGDLENTKALTMEIQQEQSRLKTLHVVITSQEQLQRTQSQLLQMVLQGWKFNGGSLYYFSSVKKSWHEAEQFCVSQGAHLASVASKEEQAFLVEFTSKVYYWIGLTDRGTEGSWRWTDGTPFNAAQNKAPGSKGSCPLRKYIIVNSGMGACSFIDTPPCPWILSN", "length": 589 }, "evidence": [ { "id": "HGNC:25357", "url": "https://alliancegenome.org/gene/HGNC:25357#orthology", "database": "AGR" }, { "id": "FB:FBgn0030050", "url": "https://alliancegenome.org/gene/FB:FBgn0030050#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VBX4-1", "protein_name": "C-type lectin domain family 4 member K", "gene_name": "Cd207", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPEAEMKEEAPEAHFTVDKQNISLWPREPPPKQDLSPVLRKPLCICVAFTCLALVLVTSIVLQAVFYPRLMGKILDVKSDAQMLKGRVDNISTLGSDLKTERGRVDDAEVQMQIVNTTLKRVRSQILSLETSMKIANDQLQILTMSWGEVDSLSAKIPELKRDLDKASALNTKVQGLQNSLENVNKLLKQQSDILEMVARGWKYFSGNFYYFSRTPKTWYSAEQFCISRKAHLTSVSSESEQKFLYKAADGIPHWIGLTKAGSEGDWYWVDQTSFNKEQSRRFWIPGEPNNAGNNEHCANIRVSALKCWNDGPCDNTFLFICKRPYVQTTE", "length": 331 }, "evidence": [ { "id": "RGD:1565913", "url": "https://alliancegenome.org/gene/RGD:1565913#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WTT0-1", "protein_name": "C-type lectin domain family 4 member C", "gene_name": "CLEC4C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVPEEEPQDREKGLWWFQLKVWSMAVVSILLLSVCFTVSSVVPHNFMYSKTVKRLSKLREYQQYHPSLTCVMEGKDIEDWSCCPTPWTSFQSSCYFISTGMQSWTKSQKNCSVMGADLVVINTREEQDFIIQNLKRNSSYFLGLSDPGGRRHWQWVDQTPYNENVTFWHSGEPNNLDERCAIINFRSSEEWGWNDIHCHVPQKSICKMKKIYI", "length": 213 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050311-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050311-4#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8WXI8-1", "protein_name": "C-type lectin domain family 4 member D", "gene_name": "CLEC4D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGLEKPQSKLEGGMHPQLIPSVIAVVFILLLSVCFIASCLVTHHNFSRCKRGTGVHKLEHHAKLKCIKEKSELKSAEGSTWNCCPIDWRAFQSNCYFPLTDNKTWAESERNCSGMGAHLMTISTEAEQNFIIQFLDRRLSYFLGLRDENAKGQWRWVDQTPFNPRRVFWHKNEPDNSQGENCVVLVYNQDKWAWNDVPCNFEASRICKIPGTTLN", "length": 215 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050311-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050311-4#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JKF4-1", "protein_name": "C-type lectin domain family 6 member A", "gene_name": "Clec6a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVQERQSQGKGVCWTLRLWSAAVISMLLLSTCFIASCVVTYQFIMDQPSRRLYELHTYHSSLTCFSEGTMVSEKMWGCCPNHWKSFGSSCYLISTKENFWSTSEQNCVQMGAHLVVINTEAEQNFITQQLNESLSYFLGLSDPQGNGKWQWIDDTPFSQNVRFWHPHEPNLPEERCVSIVYWNPSKWGWNDVFCDSKHNSICEMKKIYL", "length": 209 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050311-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050311-4#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9R0Q8-1", "protein_name": "C-type lectin domain family 4 member E", "gene_name": "Clec4e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSTKSPASHHTERGCFKNSQVLSWTIAGASILFLSGCFITRCVVTYRSSQISGQNLQPHRNIKELSCYSEASGSVKNCCPLNWKHYQSSCYFFSTTTLTWSSSLKNCSDMGAHLVVIDTQEEQEFLFRTKPKRKEFYIGLTDQVVEGQWQWVDDTPFTESLSFWDAGEPNNIVLVEDCATIRDSSNSRKNWNDIPCFYSMPWICEMPEISPLD", "length": 214 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050311-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050311-4#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UJ71-1", "protein_name": "C-type lectin domain family 4 member K", "gene_name": "CD207", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTVEKEAPDAHFTVDKQNISLWPREPPPKSGPSLVPGKTPTVRAALICLTLVLVASVLLQAVLYPRFMGTISDVKTNVQLLKGRVDNISTLDSEIKKNSDGMEAAGVQIQMVNESLGYVRSQFLKLKTSVEKANAQIQILTRSWEEVSTLNAQIPELKSDLEKASALNTKIRALQGSLENMSKLLKRQNDILQVVSQGWKYFKGNFYYFSLIPKTWYSAEQFCVSRNSHLTSVTSESEQEFLYKTAGGLIYWIGLTKAGMEGDWSWVDDTPFNKVQSVRFWIPGEPNNAGNNEHCGNIKAPSLQAWNDAPCDKTFLFICKRPYVPSEP", "length": 328 }, "evidence": [ { "id": "RGD:1565913", "url": "https://alliancegenome.org/gene/RGD:1565913#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9ULY5-1", "protein_name": "C-type lectin domain family 4 member E", "gene_name": "CLEC4E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNSSKSSETQCTERGCFSSQMFLWTVAGIPILFLSACFITRCVVTFRIFQTCDEKKFQLPENFTELSCYNYGSGSVKNCCPLNWEYFQSSCYFFSTDTISWALSLKNCSAMGAHLVVINSQEEQEFLSYKKPKMREFFIGLSDQVVEGQWQWVDGTPLTKSLSFWDVGEPNNIATLEDCATMRDSSNPRQNWNDVTCFLNYFRICEMVGINPLNKGKSL", "length": 219 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050311-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050311-4#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9UMR7-1", "protein_name": "C-type lectin domain family 4 member A", "gene_name": "CLEC4A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSEITYAEVRFKNEFKSSGINTASSAASKERTAPHKSNTGFPKLLCASLLIFFLLLAISFFIAFVIFFQKYSQLLEKKTTKELVHTTLECVKKNMPVEETAWSCCPKNWKSFSSNCYFISTESASWQDSEKDCARMEAHLLVINTQEEQDFIFQNLQEESAYFVGLSDPEGQRHWQWVDQTPYNESSTFWHPREPSDPNERCVVLNFRKSPKRWGWNDVNCLGPQRSVCEMMKIHL", "length": 237 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050311-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050311-4#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VIX1-1", "protein_name": "Galactose-specific C-type lectin, isoform A", "gene_name": "Lectin-galC1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLKLTVLLITLLVIAKTGWTREKFSIQVNEGNTFGALVKAEPFTKINDGYYFFGTESLNWYEAYEKCRELNSELVTFETDQEFDAVTAFLTANGSRLTYWTSGNDLAKTGSHRWFTNAQRISSLRWARNQPDNAGQKEHCIHLGYIYKDSRKFELNDRPCSQDPNSLFKYICEAPEMETISIVVWK", "length": 186 }, "evidence": [ { "id": "RGD:1565913", "url": "https://alliancegenome.org/gene/RGD:1565913#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "Q9W3D8", "url": "https://www.uniprot.org/uniprotkb/Q9W3D8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "Q9W3D8", "url": "https://www.uniprot.org/uniprotkb/Q9W3D8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "Q9W3D8", "url": "https://www.uniprot.org/uniprotkb/Q9W3D8" } ], "pmid": "" }, { "name": "pattern recognition receptor activity", "id": "GO:0038187", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038187", "evidence": [ { "database": "UniProtKB", "id": "Q9W3D8", "url": "https://www.uniprot.org/uniprotkb/Q9W3D8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9W3D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3D8" }, { "id": "PS50041", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50041" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C-type lectin", "eco_id": "ECO_0000259", "start_pos": 51, "end_pos": 174, "start_aa": "Ile", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9W3E7-1", "uniprot_ac": "Q9W3E7", "uniprot_id": "Q9W3E7_DROME", "mass": { "chemical_mass": 36404.0, "monoisotopic_mass": 36404.0 }, "refseq": { "ac": "NP_572485", "name": "chorion protein c at 7F", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572485" }, "gene_names": [ { "name": "Cp7Fc", "type": "recommended", "evidence": [ { "id": "Q9W3E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3E7" } ] }, { "name": "CG15351", "type": "synonym", "evidence": [ { "id": "NP_572485", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572485" }, { "id": "Q9W3E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3E7" } ] }, { "name": "Cp7Fc", "type": "synonym", "evidence": [ { "id": "NP_572485", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572485" } ] }, { "name": "Dmel\\CG15351", "type": "synonym", "evidence": [ { "id": "NP_572485", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572485" }, { "id": "Q9W3E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3E7" } ] }, { "name": "Dmel_CG15351", "type": "synonym", "evidence": [ { "id": "Q9W3E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3E7" } ] }, { "name": "D", "type": "synonym", "evidence": [ { "id": "NP_572485", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572485" }, { "id": "Q9W3E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3E7" } ] }, { "name": "E", "type": "synonym", "evidence": [ { "id": "NP_572485", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572485" }, { "id": "Q9W3E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3E7" } ] }, { "name": "s37", "type": "synonym", "evidence": [ { "id": "NP_572485", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572485" }, { "id": "Q9W3E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3E7" } ] } ], "protein_names": [ { "name": "CG15351-PA", "type": "synonym", "evidence": [ { "id": "NP_572485", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572485" } ] }, { "name": "Chorion protein c at 7F", "type": "synonym", "evidence": [ { "id": "Q9W3E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3E7/entry#names_and_taxonomy" } ] }, { "name": "Cp7Fc-PA", "type": "synonym", "evidence": [ { "id": "NP_572485", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572485" } ] }, { "name": "chorion protein c at 7F", "type": "synonym", "evidence": [ { "id": "NP_572485", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572485" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W3E7", "url": "https://www.uniprot.org/uniprotkb/Q9W3E7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Cp7Fc", "url": 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"id": "GGTNEEY", "url": "https://omabrowser.org/oma/group/GGTNEEY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W3E7", "url": "https://www.orthodb.org/?gene=Q9W3E7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "NP_572485", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572485", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W3E7", "url": "https://www.uniprot.org/uniprotkb/Q9W3E7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W3E7-1", "url": "https://www.uniprot.org/uniprotkb/Q9W3E7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAADGSWPILLLLVSTQAIIHAENLSESTPGPDEEYNVSTTPGAPLEETTNRLAARVEPYDKGDREQYDVIDVATATGTVMGKPRSGQTTRIYTTGEVDESFWLKHLGDDFKHAIHLQVGGTNEEYNRLINRTQNGVHEEVHHEYLPGAERPGSAVQPPSPLPAPHQSRPAYRQGFDNRAMAMKQQYLIHQQTQQSHPAQQRYNYAQQHAQHYAPQPQLQPQPQPQPQYPQHTPHRNTYAMPQNYGQQNYKPQSYIINSSEDQLHAEQSNPSPMKSAGEDRQHHEEEFDSFGGQLNFKSPFNDYGSRPARDLTYLLYKRGL", "length": 321, "header": "tr|Q9W3E7-1|Q9W3E7_DROME Isoform 1 of Chorion protein c at 7F OS=Drosophila melanogaster OX=7227 GN=Cp7Fc PE=4 SV=2 CANONICAL=Q9W3E7-1" }, "isoforms": [ { "isoform_ac": "Q9W3E7-1", "url": "https://www.uniprot.org/uniprotkb/Q9W3E7/entry#Q9W3E7-1", "sequence": { "sequence": "MAADGSWPILLLLVSTQAIIHAENLSESTPGPDEEYNVSTTPGAPLEETTNRLAARVEPYDKGDREQYDVIDVATATGTVMGKPRSGQTTRIYTTGEVDESFWLKHLGDDFKHAIHLQVGGTNEEYNRLINRTQNGVHEEVHHEYLPGAERPGSAVQPPSPLPAPHQSRPAYRQGFDNRAMAMKQQYLIHQQTQQSHPAQQRYNYAQQHAQHYAPQPQLQPQPQPQPQYPQHTPHRNTYAMPQNYGQQNYKPQSYIINSSEDQLHAEQSNPSPMKSAGEDRQHHEEEFDSFGGQLNFKSPFNDYGSRPARDLTYLLYKRGL", "length": 321, "header": "tr|Q9W3E7-1|Q9W3E7_DROME Isoform 1 of Chorion protein c at 7F OS=Drosophila melanogaster OX=7227 GN=Cp7Fc PE=4 SV=2 CANONICAL=Q9W3E7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W3E7", "url": "https://www.uniprot.org/uniprotkb/Q9W3E7" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W3E7", "url": "https://www.uniprot.org/uniprotkb/Q9W3E7" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3E7", "url": "https://www.uniprot.org/uniprotkb/Q9W3E7" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3E7", "url": "https://www.uniprot.org/uniprotkb/Q9W3E7" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W3E7", "url": "https://www.uniprot.org/uniprotkb/Q9W3E7" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W3E7", "url": "https://www.uniprot.org/uniprotkb/Q9W3E7" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W3E7", "url": "https://www.uniprot.org/uniprotkb/Q9W3E7" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3E7", "url": "https://www.uniprot.org/uniprotkb/Q9W3E7" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3E7", "url": "https://www.uniprot.org/uniprotkb/Q9W3E7" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"MTSSLAKIEDFPSDPVEFFKEILQEAAKGHPDGFIQEMNLATVDEEFGVLNRTVLYRGLTQDNCVFYITHRYVRNFKNLQANPKACITFYMPDVKDKAGNQNAWQVRLIGATAVELDQSEMDALWAKENLAAQIRGHICPCGEPINYDDLKAKHDQFLLDHRGKSIERPASYTAWKFQPQRWDFLKVGLDQIADRVQYRLQKDGKWKSMHVST", "length": 213, "header": "tr|Q9W3G8-1|Q9W3G8_DROME Isoform 1 of pyridoxal 5'-phosphate synthase OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG15343 PE=4 SV=1 CANONICAL=Q9W3G8-1" }, "isoforms": [ { "isoform_ac": "Q9W3G8-1", "url": "https://www.uniprot.org/uniprotkb/Q9W3G8/entry#Q9W3G8-1", "sequence": { "sequence": "MTSSLAKIEDFPSDPVEFFKEILQEAAKGHPDGFIQEMNLATVDEEFGVLNRTVLYRGLTQDNCVFYITHRYVRNFKNLQANPKACITFYMPDVKDKAGNQNAWQVRLIGATAVELDQSEMDALWAKENLAAQIRGHICPCGEPINYDDLKAKHDQFLLDHRGKSIERPASYTAWKFQPQRWDFLKVGLDQIADRVQYRLQKDGKWKSMHVST", "length": 213, "header": "tr|Q9W3G8-1|Q9W3G8_DROME Isoform 1 of pyridoxal 5'-phosphate synthase OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG15343 PE=4 SV=1 CANONICAL=Q9W3G8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W3G8", "url": "https://www.uniprot.org/uniprotkb/Q9W3G8" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W3G8", "url": "https://www.uniprot.org/uniprotkb/Q9W3G8" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3G8", "url": "https://www.uniprot.org/uniprotkb/Q9W3G8" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3G8", "url": "https://www.uniprot.org/uniprotkb/Q9W3G8" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W3G8", "url": "https://www.uniprot.org/uniprotkb/Q9W3G8" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W3G8", "url": "https://www.uniprot.org/uniprotkb/Q9W3G8" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W3G8", "url": "https://www.uniprot.org/uniprotkb/Q9W3G8" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3G8", "url": "https://www.uniprot.org/uniprotkb/Q9W3G8" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3G8", "url": "https://www.uniprot.org/uniprotkb/Q9W3G8" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF18084", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_572455", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572455", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W3I7", "url": "https://www.uniprot.org/uniprotkb/Q9W3I7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W3I7-1", "url": "https://www.uniprot.org/uniprotkb/Q9W3I7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDTTMPMGMVPNSLNPILNPRPLPIPVTKPRTKLQPDEPHDGVLAFNKGKVPPPVSSRPIPLQRAMSEVRDALRAQPQASDIRLLIFTAAASSVEHERTLIPVPPQFQAAPGSGCQVDRLRHAVADNWPSCRIMLDCPSTDEQYAALMPDDVDALHLLHWILVATPSSPTLRRMSGLHLRRLCRFLGLARPTLEPGHLLSISYERNVQRLGDSSPRPRSSYAYLGLPFQYLYRFLATGRLEQPPGVAIRLYAQPETALVHCDELSSLPQQQHVQSEEQSSSQSIAEREQSGNSSSLCWRNSTLTAPQRALVICELPSELDESIAHSPEKHFLEYFVQESLSLRPCYLLLFDEAVASNIMFVWPGKCIELEHPGPSMVQRSRIRIMNIVRNLSNRLGAVRRALAAI", "length": 405, "header": "tr|Q9W3I7-1|Q9W3I7_DROME Isoform 1 of PARP16 N-terminal domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG15337 PE=4 SV=1 CANONICAL=Q9W3I7-1" }, "isoforms": [ { "isoform_ac": "Q9W3I7-1", "url": "https://www.uniprot.org/uniprotkb/Q9W3I7/entry#Q9W3I7-1", "sequence": { "sequence": "MDTTMPMGMVPNSLNPILNPRPLPIPVTKPRTKLQPDEPHDGVLAFNKGKVPPPVSSRPIPLQRAMSEVRDALRAQPQASDIRLLIFTAAASSVEHERTLIPVPPQFQAAPGSGCQVDRLRHAVADNWPSCRIMLDCPSTDEQYAALMPDDVDALHLLHWILVATPSSPTLRRMSGLHLRRLCRFLGLARPTLEPGHLLSISYERNVQRLGDSSPRPRSSYAYLGLPFQYLYRFLATGRLEQPPGVAIRLYAQPETALVHCDELSSLPQQQHVQSEEQSSSQSIAEREQSGNSSSLCWRNSTLTAPQRALVICELPSELDESIAHSPEKHFLEYFVQESLSLRPCYLLLFDEAVASNIMFVWPGKCIELEHPGPSMVQRSRIRIMNIVRNLSNRLGAVRRALAAI", "length": 405, "header": "tr|Q9W3I7-1|Q9W3I7_DROME Isoform 1 of PARP16 N-terminal domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG15337 PE=4 SV=1 CANONICAL=Q9W3I7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W3I7", "url": "https://www.uniprot.org/uniprotkb/Q9W3I7" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W3I7", "url": "https://www.uniprot.org/uniprotkb/Q9W3I7" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3I7", "url": "https://www.uniprot.org/uniprotkb/Q9W3I7" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3I7", "url": "https://www.uniprot.org/uniprotkb/Q9W3I7" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W3I7", "url": "https://www.uniprot.org/uniprotkb/Q9W3I7" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W3I7", "url": "https://www.uniprot.org/uniprotkb/Q9W3I7" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W3I7", "url": "https://www.uniprot.org/uniprotkb/Q9W3I7" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3I7", "url": "https://www.uniprot.org/uniprotkb/Q9W3I7" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3I7", "url": "https://www.uniprot.org/uniprotkb/Q9W3I7" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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} } ], "crossref": [ { "id": "FB:FBgn0029997", "url": "https://alliancegenome.org/gene/FB:FBgn0029997", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0029997", "url": "https://bgee.org/?page=gene&gene_id=FBgn0029997", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11849", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11849", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0029997", "url": "https://flybase.org/reports/FBgn0029997", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "31729", "url": "https://www.ncbi.nlm.nih.gov/gene/31729", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018556", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018556", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030125", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030125", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035514", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035514", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG2258", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG2258", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CFARIFC", "url": "https://omabrowser.org/oma/group/CFARIFC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W3K6", "url": "https://www.orthodb.org/?gene=Q9W3K6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13357", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13357", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13357:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13357:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09431", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09431", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-2029482", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-2029482", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-5663213", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-5663213", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001285000", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285000", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W3K6", "url": "https://www.uniprot.org/uniprotkb/Q9W3K6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W3K6-1", "url": "https://www.uniprot.org/uniprotkb/Q9W3K6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLKALYDFQAVYPKTISFDEGEYFILYQTSARQRNWWQVVSMKGNIGFVPSNYVMKIKVEHDFLISFLNSSIESLEKCTDHEINGIMSKDELLDRLREKKHTMERLYAESSERDGDSSLSYSHSYSDKGSHRHSHPHPTQSQTQLHSQHRQHSPPPSGGSVGSQRLDMSKKSMSSPAVGSSCGLPQNQGMIESPSMGSMQFQGSSCTIQTPQQQQPLPAPPAPAPSPSAASATPTAASTSKAATGGDVAQDNSITSEPSETTTTTTTTSEDVVTTYKETSQMSTSQQHKPQNGSTASASISASASASALRSNGGNGKANGSATALHQELQQEEADSAPDKSDDASAVQSDDGCPANGDSADNSQALDSIDSPSHRQRGLSLGRIEEGATGGGQLKVESSDVYQIVDALRRNTNLSFDLSCEALRVVLTSLEQLYNGAINPYLEAVAVHVTGKVATPKELLGITHDAKRLQYLFAQLADCKNDTEQRTWMLYEDEEDIIQFLEELVEILINADESISCYEMSCDQYQMFINLVQYYQMETRWSIKRLLLKTFTAACHLDYIIVDILLTSVLPLEIVEDMKTHFSNLDRFKQLVKMLTIIFSLGQPMPVNHQDYLGVHFASFLLEIVEGNNPEVLVDMVIALILAFNQQFSEHTYNVIIEGMQNLPSAKVFTEKLLLLLNREDDPTRLLKHPNEHMNTVLRMFIDIFSHPDTAGMFYTNDIKVLIDIVVRQLSDLDAGSTTRPCYLELCRRILRNTNYQEHQHRKHDLMKIFTRIFCEETECSASDQQLVREIANEFPQLFKA", "length": 801, "header": "tr|Q9W3K6-1|Q9W3K6_DROME Isoform 1 of SH3 domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG2258 PE=1 SV=1 CANONICAL=Q9W3K6-1" }, "isoforms": [ { "isoform_ac": "Q9W3K6-1", "url": "https://www.uniprot.org/uniprotkb/Q9W3K6/entry#Q9W3K6-1", "sequence": { "sequence": "MLKALYDFQAVYPKTISFDEGEYFILYQTSARQRNWWQVVSMKGNIGFVPSNYVMKIKVEHDFLISFLNSSIESLEKCTDHEINGIMSKDELLDRLREKKHTMERLYAESSERDGDSSLSYSHSYSDKGSHRHSHPHPTQSQTQLHSQHRQHSPPPSGGSVGSQRLDMSKKSMSSPAVGSSCGLPQNQGMIESPSMGSMQFQGSSCTIQTPQQQQPLPAPPAPAPSPSAASATPTAASTSKAATGGDVAQDNSITSEPSETTTTTTTTSEDVVTTYKETSQMSTSQQHKPQNGSTASASISASASASALRSNGGNGKANGSATALHQELQQEEADSAPDKSDDASAVQSDDGCPANGDSADNSQALDSIDSPSHRQRGLSLGRIEEGATGGGQLKVESSDVYQIVDALRRNTNLSFDLSCEALRVVLTSLEQLYNGAINPYLEAVAVHVTGKVATPKELLGITHDAKRLQYLFAQLADCKNDTEQRTWMLYEDEEDIIQFLEELVEILINADESISCYEMSCDQYQMFINLVQYYQMETRWSIKRLLLKTFTAACHLDYIIVDILLTSVLPLEIVEDMKTHFSNLDRFKQLVKMLTIIFSLGQPMPVNHQDYLGVHFASFLLEIVEGNNPEVLVDMVIALILAFNQQFSEHTYNVIIEGMQNLPSAKVFTEKLLLLLNREDDPTRLLKHPNEHMNTVLRMFIDIFSHPDTAGMFYTNDIKVLIDIVVRQLSDLDAGSTTRPCYLELCRRILRNTNYQEHQHRKHDLMKIFTRIFCEETECSASDQQLVREIANEFPQLFKA", "length": 801, "header": "tr|Q9W3K6-1|Q9W3K6_DROME Isoform 1 of SH3 domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG2258 PE=1 SV=1 CANONICAL=Q9W3K6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W3K6", "url": "https://www.uniprot.org/uniprotkb/Q9W3K6" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W3K6", "url": "https://www.uniprot.org/uniprotkb/Q9W3K6" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3K6", "url": "https://www.uniprot.org/uniprotkb/Q9W3K6" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3K6", "url": "https://www.uniprot.org/uniprotkb/Q9W3K6" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W3K6", "url": "https://www.uniprot.org/uniprotkb/Q9W3K6" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W3K6", "url": "https://www.uniprot.org/uniprotkb/Q9W3K6" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W3K6", "url": "https://www.uniprot.org/uniprotkb/Q9W3K6" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3K6", "url": "https://www.uniprot.org/uniprotkb/Q9W3K6" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3K6", "url": "https://www.uniprot.org/uniprotkb/Q9W3K6" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W3K6", "url": "https://www.uniprot.org/uniprotkb/Q9W3K6" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W3K6", "url": "https://www.uniprot.org/uniprotkb/Q9W3K6" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG2258", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG2258", "resource": "KEGG Pathway" }, { "id": "R-DME-2029482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-2029482", "resource": "Reactome", "description": "Regulation of actin dynamics for phagocytic cup formation" }, { "id": "R-DME-5663213", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-5663213", "resource": "Reactome", "description": "RHO GTPases Activate WASPs and WAVEs" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7G0E9-1", "protein_name": "NCK-interacting protein with SH3 domain isoform X1", "gene_name": "Nckipsd", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEDFADSCIHLTPSEKLLRLPLELSMVAYAHSLSIWKGCHDFQASFSGTKAHLKKPATQPTKKTRKLHSGVCSALLCSSCVAWRALCAGQNHSSNPHLLHGMEQDVLQAIDRAIEAVHNTAMRDGGKYSLEQRGVLQKLIHHRKETLSRRGPSASSASVMTPSTSDHHLDSAVSRQPNGLCRTGFERQHSLPSSEHLGTDGALYQVPPQPRRAAPATPPPPVKRRDREALVISGSGGRTTIPSGGSSVSSGSSVSSTSMDTLCTGSGPSDLGPSSSPTPPPVPRRAAHTAVSQAQPSPSKAPSPEPPAEEVAADTNSASDALEALDALSLETTEEKPAAETVVPRTIGAELMELVRRNTGLSHELCRVAIGVVVGHIQASVPSSSPVMEQVLLSLVEGKDLSTALPSGQVCHDQQRLEVIFADLARRKDDAQQRSWALYEDEDVIRCYLEELLHILTDADPGVCKKMCRRDEFESVLALVAYYQMEHRASLRLLLLKCFGAMCSLDAAIISTLVSSVLPVELARDMQTDTQDHQKLCYSALILAMVFSMGEAVPYAHYEHLGTPFAQFLLSVVEDGLPLDTTEQLPDLCMNLLLALNLHLTAPDQNVIMAALSKHTNVKIFSEKLLLLLNRGDDPVRIFKHEPQPPHSVLKFLQDVFGSPATASIFYHTDMMALIDITVRQIADLSPGDKSKDHGKPFTLGMLGQEDEFGGRCVDLRRLRYAGDDKQLDILAGHSRTDLCEMYETGLLFEVMGVIETVRSQGF", "length": 763 }, "evidence": [ { "id": "Q9W3K6", "url": "https://omabrowser.org/oma/group/Q9W3K6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AB13A8I5-1", "protein_name": "NCK-interacting protein with SH3 domain", "gene_name": "nckipsd", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MYHSLFSFSSAEQNALHFPAGEAFLILERSSAHWWLATRCSSGETGYIPAAYLQKIPAPEQDEVLQSIDRAIEAIHNVAMTNGGKYNLEQRDVLQKLIHHRKETLSRRSPTPSGVKSKIPSSSSEASLSQTPPPNGLSRTPPPNGLSRAHSCQGSKPMSERTASVPGLYQVPPHPRRAAPDTPPALDKQRNDPPMSLRVSSTSPTPSSVAPPGPSLSISSASLDSGSSQSGVSSDVSLPSVSSTPPPVPKRGKAPPPPPPDQSPQEEPVKKSPAPQPIRSQAPPPPPDLSIKTLTPQPISSQAPPPPTDLSKESPVPQPMGLQPAAEPHPEVEWPLAPPPVSLSPPAGSAQCALPLTIGAELTELVRRNTGLSCELSRVAVGVVVGRLQGALPGAQVQLEQVLQSLALSTDLPLGQVCHDQQRLQVIFGDLARHREDSQQRSWALHEDHALIACYLEELLQILTDADAEVCRKMCRVNEFEPVLSLVSYYQMEHRVSLRLWLLKVFGAMCGLDAALISTLLNSVLTMELARDLQTDTDEHEKMCYSALLMAMVFSTGEQIPLHHYEHLNAGFLQFLLDVIEDGLPTDSTEQLPDLFINVLLAFNLHLSVPDSNIVMQTLMKRDNAKILSEKLLLLLNRGEDPVCVFSHAPAAPHAVVKFLQDVFSSADSAQIFYRSDLMVLIDITVRQISDLEPGDRMRAQYLSLMLSVMRCSEYQEHRHRLADLRAALQRILGEEESGAAERSIVLQIYEEFPDTCSS", "length": 759 }, "evidence": [ { "id": "MGI:1931834", "url": "https://alliancegenome.org/gene/MGI:1931834#orthology", "database": "AGR" }, { "id": "HGNC:15486", "url": "https://alliancegenome.org/gene/HGNC:15486#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZWX4-1", "protein_name": "NCK interacting protein with SH3 domain", "gene_name": "Nckipsd", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLEPTHPWGGAFGSRACARVACHGAGRGERGTQGLGFPALQPSSRTQHRRGAERPGLMYRALYAFRSAEPNAMAFAAGETFLVLERSSTHWWLAARARSGETGYVPPAYLHRLQGMEQDVLQAIDRAIEAVHNTAMRDGGKYSLEQRGVLQKLIHHRKETLSRRGTSAASASVMTPSTSDHHLDTAVSRQPNGVCRTGFERQHSLPSSEHLGTDGALYQVPPQPRRAAPATPPPPVKRRDREALVISGSGGRTAVPSGGSSVSSGSSVSSTSMDTLYTGSSPSELGPSCSPTPPPVPRRSAHTTVSQAQPSPSKAPSPEPPAEEVAAETNSAPDDLEALDALSPETTEEKPATETVVPRTIGAELMELVRRNTGLSHELCRVAIGVVVGHIQASVPASSPVMEQVLLSLVEGKDLSTALPSGQVCHDQQRLEVIFADLARRKDDAQQRSWALYEDEDVIRCYLEELLHILTDADPEVCKKMCKRSDFESVLALVAYYQMEHRASLRLLLLKCFGAMCSLDAAIISTLVSSVLPVELARDMQTDTQDHQKLCYSALVLAMVFSMGEAVPYAHYEHLGTPFAQFLLSIVEDGLPLDATEQLPDLCMNLLLALNLHLTAPDQNVIMAALSKHTNVKIFSEKLLLLLNRGDDPVRIFRHEPQPPHSVLKFLQDVFSSAATASIFYHTDMMALIDITVRQIADLSPGDKLRMEYLSLMHAVVRSTPYLQHRHRLSDLQATLRRILTEEETSPQCQMDRMIVQEMYKEFPDLGEVPS", "length": 771 }, "evidence": [ { "id": "RGD:1311323", "url": "https://alliancegenome.org/gene/RGD:1311323#orthology", "database": "AGR" }, { "id": "MGI:1931834", "url": "https://alliancegenome.org/gene/MGI:1931834#orthology", "database": "AGR" }, { "id": "HGNC:15486", "url": "https://alliancegenome.org/gene/HGNC:15486#orthology", "database": "AGR" }, { "id": "FB:FBgn0029997", "url": "https://alliancegenome.org/gene/FB:FBgn0029997#orthology", "database": "AGR" }, { "id": "SGD:S000002305", "url": "https://alliancegenome.org/gene/SGD:S000002305#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1C7M3-1", "protein_name": "NCK interacting protein with SH3 domain", "gene_name": "NCKIPSD", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MYRALYSFRSAEPNSLPFAAGETFLLLERSNQHWWLVTRAGSGETGYAPASYLQRLQVLEQDVVLQSIDRAIEAVHNAAMKNGGKYNLEQRDVLQKLIHHRKETVSRKSHSPSPQGMVMTQSSSDHHLDAARQPNGVCRTGYERHHSLPNTEFEEEDEGPYQIPPQPRRAAPITPPPPEKRKSAQMAAPLKNAVEIIPGSASSASSVSTTSLDTLYTPSSASDAALPTAASSPATTPPPVPSRSVHTTITRNLDTGPAAHSRYTSSPKDGASKSPQAKRAAPAPPSDVGTPRSHAADGEKTLQGKKAAPAAPANLEAFSNLCLDDKKAAVAEPMPPEPSGLVASVPKTIGAELIELVRRNTHLSYELSRVAIGVVIGHIQTLVPATSGIMEQILISVVESKDLSSGLPSGQICHDEQRLEVIFADLARHKDDAQQRSWALYEDENVICCYLEELLRILTDADPEVCKKMCKKNEFESILSLVAYYQMEHRVPLRLLLLKCFGAMCNLDAAIISTLVNSVLPMELARDMQTHTQDHQKMCYSALVLAMIFSMGEPLPYHHYEHLNSQFVQFLLDVIEDGLPSDTTDQLPDLFINVLLAFNLHIPVPEHSVIMTTISKHSNVKTFTEKLLLLLNRGDDPVCIFKHQPQPPHSVLKFLQDIFASKDTASIFYHTDMMVLIDILVRQIADLSPGDKLRMEYLSLMHAIIRSTPYLQHQHRLSDLQGILQRILGEEEEEQQCQMDKLIILEIYKEFPEISPGTS", "length": 759 }, "evidence": [ { "id": "Q9W3K6", "url": "https://omabrowser.org/oma/group/Q9W3K6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q12342-1", "protein_name": "Protein LDB17", "gene_name": "LDB17", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MILDPLSPNIENHTQDEIIEFWEKTESIANIPKENLDESHVNSSLVAYLKFATDSYKVFINTDRDLYRMSLILLESSLFEFKKEFCLSKLQSLLNIDLLEMNMKFIIVYILLCEAKKNVYSLEIMLKFQGFTVFYNTLYTQFAYLSKYGKERTVASKHQYNSNNSSTGTSLDSLDRSLTDIDLGIIDEMKQISTVLMDLLFQIMKYCKCVIANLQIVDDFFVYYMMESMRSDTMDDMFNNAEFKLLLALNEQYMMFAKEYDIENKVYKYLINGSVSRCFTELLLLKFNRASDPPLQIMMCKIIYLILTPRGDYSPMNFFYTNDLRVLIDVLIRELQNISEDEEVLRNTLLRVLIPLLKNTQLSKTHYRKDDLNKLLNYLSTLDNICVDSPALHEHQVTVALSRKCLQQIPWLETPSTPSDGGSSVSSNNTSRNSSIVALGTPDNQNILARKGHLYSNRELDVSAESLTKRKAKAPPPPPPPPPSRKCGTPK", "length": 491 }, "evidence": [ { "id": "RGD:1311323", "url": "https://alliancegenome.org/gene/RGD:1311323#orthology", "database": "AGR" }, { "id": "MGI:1931834", "url": "https://alliancegenome.org/gene/MGI:1931834#orthology", "database": "AGR" }, { "id": "HGNC:15486", "url": "https://alliancegenome.org/gene/HGNC:15486#orthology", "database": "AGR" }, { "id": "FB:FBgn0029997", "url": "https://alliancegenome.org/gene/FB:FBgn0029997#orthology", "database": "AGR" }, { "id": "SGD:S000002305", "url": "https://alliancegenome.org/gene/SGD:S000002305#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q9ESJ4-1", "protein_name": "NCK-interacting protein with SH3 domain", "gene_name": "Nckipsd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MYRALYAFRSAEPNAMAFAAGETFLVLERSSTHWWLAARARSGETGYVPPAYLHRLQGMEQDVLQAIDRAIEAVHNTAMRDGGKYSLEQRGVLQKLIHHRKETLSRRGTSASSATVMTPSTSDHHLDAAVSRQPNGVCRTGFERQHSLPSSEHLGTDGALYQVPPQPRRAAPTTPPPPVKRRDREALVISGSGGRTAIPSGGSSVSSGSSASSTSMDTLYTGSSPSELGPSCSPTPPPVPRRGAHTTVSQPQPSPSKAPSPEPPTEEVAAETNSTPDDLEAQDALSPETTEEKAAAETVVPRTIGAELMELVRRNTGLSHELCRVAIGVVVGHIQATVPASSPIMEQVLLSLVEGKDLSTALPSGQVCHDQQRLEVIFADLARRKDDAQQRSWALYEDEDVIRCYLEELLHILTDADPEVCKKMCKRSDFESVLALVAYYQMEHRASLRLLLLKCFGAMCSLDAAIISTLVSSVLPVELARDMQTDTQDHQKLCYSALVLAMVFSMGEAVPYAHYEHLGTPFAQFLLSIVEDGLPMDTTEQLPDLCMNLLLALNLHLTAPEQNVIMAALSRHTNVKIFSEKLLLLLNRGDDPVRIFRHEPQPPHSVLKFLQDVFSSSATAAIFYHTDMMALIDITVRQIADLSPGDKLRMEYLSLMHAVVRSTPYLQHRHRLSDLQATLRRILTEEEASPQCQMDRMIVQEMYKEFPDLGEVPS", "length": 714 }, "evidence": [ { "id": "RGD:1311323", "url": "https://alliancegenome.org/gene/RGD:1311323#orthology", "database": "AGR" }, { "id": "MGI:1931834", "url": "https://alliancegenome.org/gene/MGI:1931834#orthology", "database": "AGR" }, { "id": "HGNC:15486", "url": "https://alliancegenome.org/gene/HGNC:15486#orthology", "database": "AGR" }, { "id": "FB:FBgn0029997", "url": "https://alliancegenome.org/gene/FB:FBgn0029997#orthology", "database": "AGR" }, { "id": "SGD:S000002305", "url": "https://alliancegenome.org/gene/SGD:S000002305#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NZQ3-1", "protein_name": "NCK-interacting protein with SH3 domain", "gene_name": "NCKIPSD", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MYRALYAFRSAEPNALAFAAGETFLVLERSSAHWWLAARARSGETGYVPPAYLRRLQGLEQDVLQAIDRAIEAVHNTAMRDGGKYSLEQRGVLQKLIHHRKETLSRRGPSASSVAVMTSSTSDHHLDAAAARQPNGVCRAGFERQHSLPSSEHLGADGGLYQIPLPSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDTLYTSSSPSEPGSSCSPTPPPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVATGTTSASDDLEALGTLSLGTTEEKAAAEAAVPRTIGAELMELVRRNTGLSHELCRVAIGIIVGHIQASVPASSPVMEQVLLSLVEGKDLSMALPSGQVCHDQQRLEVIFADLARRKDDAQQRSWALYEDEGVIRCYLEELLHILTDADPEVCKKMCKRNEFESVLALVAYYQMEHRASLRLLLLKCFGAMCSLDAAIISTLVSSVLPVELARDMQTDTQDHQKLCYSALILAMVFSMGEAVPYAHYEHLGTPFAQFLLNIVEDGLPLDTTEQLPDLCVNLLLALNLHLPAADQNVIMAALSKHANVKIFSEKLLLLLNRGDDPVRIFKHEPQPPHSVLKFLQDVFGSPATAAIFYHTDMMALIDITVRHIADLSPGDKLRMEYLSLMHAIVRTTPYLQHRHRLPDLQAILRRILNEEETSPQCQMDRMIVREMCKEFLVLGEAPS", "length": 722 }, "evidence": [ { "id": "RGD:1311323", "url": "https://alliancegenome.org/gene/RGD:1311323#orthology", "database": "AGR" }, { "id": "MGI:1931834", "url": "https://alliancegenome.org/gene/MGI:1931834#orthology", "database": "AGR" }, { "id": "HGNC:15486", "url": "https://alliancegenome.org/gene/HGNC:15486#orthology", "database": "AGR" }, { "id": "FB:FBgn0029997", "url": "https://alliancegenome.org/gene/FB:FBgn0029997#orthology", "database": "AGR" }, { "id": "SGD:S000002305", "url": "https://alliancegenome.org/gene/SGD:S000002305#orthology", "database": "AGR" }, { "id": "Q9W3K6", "url": "https://omabrowser.org/oma/group/Q9W3K6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "Q9W3K6", "url": "https://www.uniprot.org/uniprotkb/Q9W3K6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "myosin binding", "id": "GO:0017022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017022", "evidence": [ { "database": "UniProtKB", "id": "Q9W3K6", "url": "https://www.uniprot.org/uniprotkb/Q9W3K6" } ], "pmid": "" }, { "name": "Arp2/3 complex binding", "id": "GO:0071933", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071933", "evidence": [ { "database": "UniProtKB", "id": "Q9W3K6", "url": "https://www.uniprot.org/uniprotkb/Q9W3K6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 292, "end_pos": 294, "annotation": "n_glycosylation_sequon" }, { "start_pos": 319, "end_pos": 321, "annotation": "n_glycosylation_sequon" }, { "start_pos": 413, "end_pos": 415, "annotation": "n_glycosylation_sequon" }, { "start_pos": 481, "end_pos": 483, "annotation": "n_glycosylation_sequon" }, { "start_pos": 69, "end_pos": 71, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9W3K6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3K6" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 59, "start_aa": "Met", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 292, "end_pos": 294 }, { "start_pos": 319, "end_pos": 321 }, { "start_pos": 413, "end_pos": 415 }, { "start_pos": 481, "end_pos": 483 }, { "start_pos": 69, "end_pos": 71 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9W3P6-1", "uniprot_ac": "Q9W3P6", "uniprot_id": "Q9W3P6_DROME", "mass": { "chemical_mass": 44712.0, "monoisotopic_mass": 44712.0 }, "refseq": { "ac": "NP_572408", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572408" }, "gene_names": [ { "name": "Dmel\\CG10920", "type": "recommended", "evidence": [ { "id": "Q9W3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3P6" } ] }, { "name": "CG10920", "type": "synonym", "evidence": [ { "id": "NP_572408", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572408" }, { "id": "Q9W3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3P6" } ] }, { "name": "Dmel\\CG10920", "type": "synonym", "evidence": [ { "id": "NP_572408", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572408" } ] }, { "name": "Dmel_CG10920", "type": "synonym", "evidence": [ { "id": "Q9W3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3P6" } ] } ], "protein_names": [ { "name": "CG10920-PA", "type": "synonym", "evidence": [ { "id": "NP_572408", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572408" } ] }, { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "Q9W3P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3P6/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_572408", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572408" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W3P6", "url": "https://www.uniprot.org/uniprotkb/Q9W3P6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG10920", "url": "https://www.uniprot.org/uniprotkb/Q9W3P6", "locus": { "chromosome": "X", "start_pos": 7852481, "end_pos": 7854244, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0029963", "url": "https://www.ensemblgenomes.org/id/FBgn0029963" } ] } } ], "crossref": [ { "id": "FB:FBgn0029963", "url": "https://alliancegenome.org/gene/FB:FBgn0029963", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0029963", "url": "https://bgee.org/?page=gene&gene_id=FBgn0029963", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0029963", "url": "https://flybase.org/reports/FBgn0029963", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "31688", "url": "https://www.ncbi.nlm.nih.gov/gene/31688", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023395", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023395", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG10920", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG10920", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MPLYNHW", "url": "https://omabrowser.org/oma/group/MPLYNHW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W3P6", "url": "https://www.orthodb.org/?gene=Q9W3P6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10780", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10780", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10780:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10780:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00153", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00153", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_572408", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572408", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W3P6", "url": "https://www.uniprot.org/uniprotkb/Q9W3P6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W3P6-1", "url": "https://www.uniprot.org/uniprotkb/Q9W3P6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAHREYNRRDGQAEGLGLGGGDADNSVRMRHPTPPPLAVQHARSGAMVVELAVDPSRAMRSTNQQQPIDRDQLRISTEESCQGSELVVASSHLSKKIQEHRRPNQLVRFCLRLGYNTLLYPYEMAKVLIQLGHEPLQAKPFVMRLIQRRPRLFLPSVHRYVQHIQHIDGYTGMYRGLTARLAASIVDYLLGDLLLATLHFAPYKRGPKEGLSLKEFWWNLTRNSLRITTVVVITHPFYVVMVRQIAQFVGGEHVYEGLVGSLMTLAQQEGCAGLFAGMVPRLLGEWSVLFITSALSHLCRRLLPMSELQHQYNTAVIQMMASLVAYPLEVTSTCMAGTGAPLTACEPPSMPLYNHWVDCLTDLYARGGQNRGAILFWRTVPKIQLLRSKDNYTVRSI", "length": 397, "header": "tr|Q9W3P6-1|Q9W3P6_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG10920 PE=3 SV=2 CANONICAL=Q9W3P6-1" }, "isoforms": [ { "isoform_ac": "Q9W3P6-1", "url": "https://www.uniprot.org/uniprotkb/Q9W3P6/entry#Q9W3P6-1", "sequence": { "sequence": "MAHREYNRRDGQAEGLGLGGGDADNSVRMRHPTPPPLAVQHARSGAMVVELAVDPSRAMRSTNQQQPIDRDQLRISTEESCQGSELVVASSHLSKKIQEHRRPNQLVRFCLRLGYNTLLYPYEMAKVLIQLGHEPLQAKPFVMRLIQRRPRLFLPSVHRYVQHIQHIDGYTGMYRGLTARLAASIVDYLLGDLLLATLHFAPYKRGPKEGLSLKEFWWNLTRNSLRITTVVVITHPFYVVMVRQIAQFVGGEHVYEGLVGSLMTLAQQEGCAGLFAGMVPRLLGEWSVLFITSALSHLCRRLLPMSELQHQYNTAVIQMMASLVAYPLEVTSTCMAGTGAPLTACEPPSMPLYNHWVDCLTDLYARGGQNRGAILFWRTVPKIQLLRSKDNYTVRSI", "length": 397, "header": "tr|Q9W3P6-1|Q9W3P6_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG10920 PE=3 SV=2 CANONICAL=Q9W3P6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W3P6", "url": "https://www.uniprot.org/uniprotkb/Q9W3P6" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W3P6", "url": "https://www.uniprot.org/uniprotkb/Q9W3P6" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3P6", "url": "https://www.uniprot.org/uniprotkb/Q9W3P6" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3P6", "url": "https://www.uniprot.org/uniprotkb/Q9W3P6" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W3P6", "url": "https://www.uniprot.org/uniprotkb/Q9W3P6" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W3P6", "url": "https://www.uniprot.org/uniprotkb/Q9W3P6" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W3P6", "url": "https://www.uniprot.org/uniprotkb/Q9W3P6" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3P6", "url": "https://www.uniprot.org/uniprotkb/Q9W3P6" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3P6", "url": "https://www.uniprot.org/uniprotkb/Q9W3P6" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W3P6", "url": "https://www.uniprot.org/uniprotkb/Q9W3P6" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W3P6", "url": "https://www.uniprot.org/uniprotkb/Q9W3P6" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], 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Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W3P7", "url": "https://www.uniprot.org/uniprotkb/Q9W3P7" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W3P7", "url": "https://www.uniprot.org/uniprotkb/Q9W3P7" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3P7", "url": "https://www.uniprot.org/uniprotkb/Q9W3P7" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3P7", "url": "https://www.uniprot.org/uniprotkb/Q9W3P7" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W3P7", "url": "https://www.uniprot.org/uniprotkb/Q9W3P7" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W3P7", "url": "https://www.uniprot.org/uniprotkb/Q9W3P7" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W3P7", "url": "https://www.uniprot.org/uniprotkb/Q9W3P7" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3P7", "url": "https://www.uniprot.org/uniprotkb/Q9W3P7" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3P7", "url": "https://www.uniprot.org/uniprotkb/Q9W3P7" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W3P7", "url": "https://www.uniprot.org/uniprotkb/Q9W3P7" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W3P7", "url": "https://www.uniprot.org/uniprotkb/Q9W3P7" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG1402", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG1402", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1N7X1-1", "protein_name": "Carbonic anhydrase-related protein 10a isoform X1", "gene_name": "ca10a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDIIWEIFIILQANLIVCTSAQPNPPKIHEGWWAYKEVVQGSFVPVPSFWGLVNSAWNLCSVGKRQSPVNIETSHMIFDPFLTPLRLNTGGRKVGGTMYNTGRHVSLRLDKEHLVNISGGPMTYSHRLEEIRLHFGSEDGQGSEHLLNGQAFSGEVQLIHYNHELYTNYTEAAKSPNGLVIVSIFMKISETSNSFLNRMLNRDTITRITYKNDAYLLSGLNIEEVYPETASFITYEGSMTIPPCYETATWILMNKPIYVTKMQMHSMRLLSQNQPSQIFLSMSDNVRPVQPLNNRCIRTNINFSMQGKDCPNNRAQKLQYRVNEWLLK", "length": 328 }, "evidence": [ { "id": "HGNC:1369", "url": "https://alliancegenome.org/gene/HGNC:1369#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-051030-123", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-051030-123#orthology", "database": "AGR" }, { "id": "MGI:1919855", "url": "https://alliancegenome.org/gene/MGI:1919855#orthology", "database": "AGR" }, { "id": "RGD:2322930", "url": "https://alliancegenome.org/gene/RGD:2322930#orthology", "database": "AGR" }, { "id": "FB:FBgn0029962", "url": "https://alliancegenome.org/gene/FB:FBgn0029962#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M2BBM0-1", "protein_name": "Carbonic anhydrase-related protein 10 isoform X1", "gene_name": "ca10b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPHVWEFVLILNINVIFVEAQPVSSKLHDGWWAYKDVVQGSFIPVPSFWGLVNTAWNLCAIGKRQSPVNIETSRMIFDPFLNPLRLNAGQRKVSGTMYNTGRHVSLRPDKSHLVNISGGPLSYSYRLEEIRLHFGSEDNRGSEHLLNGQAFPGEVQLIHYNQDLYLNYSDAVRSPNGIAVVSIFMKISEPTNVFLNRMLNRETVTRITYKHDAYLLMGLNIEELYPETSRFITYEGSITIPPCLETATWILMNKPIYISQIEMQSLRLLSQNQPSQIFLSMGDNMRPTQTLHQRCIRTNINFSQRRDCPNNRMLRPQYRVNEWLLK", "length": 326 }, "evidence": [ { "id": "HGNC:1369", "url": "https://alliancegenome.org/gene/HGNC:1369#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080815-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080815-2#orthology", "database": "AGR" }, { "id": "MGI:1919855", "url": "https://alliancegenome.org/gene/MGI:1919855#orthology", "database": "AGR" }, { "id": "RGD:2322930", "url": "https://alliancegenome.org/gene/RGD:2322930#orthology", "database": "AGR" }, { "id": "FB:FBgn0029962", "url": "https://alliancegenome.org/gene/FB:FBgn0029962#orthology", "database": "AGR" }, { "id": "Q9W3P7", "url": "https://omabrowser.org/oma/group/Q9W3P7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E1BL46-1", "protein_name": "Carbonic anhydrase-related protein 11", "gene_name": "CA11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGAAARLSAPRALVLWAALGAAAHIGPAPDPEDWWSYKDNLQGNFVPGPPFWGLVNAAWSLCAVGKRQSPVDVELKRVLYDPFLPPLRLSTGGEKLRGTLYNTGRHVSFLPAPRPVVNVSGGPLLYSHRLSELRLLFGARDGAGSEHQINHQGFSAEVQLIHFNQELYGNLSAATRGPNGLAILSLFVNVAGSSNPFLSRLLNRDTITRISYKNDAYFLQDLSLELLFPESFGFITYQGSLSTPPCSETVTWILIDRALNITSLQMHSLRLLSQNPPSQIFQSLSGNGRPLQPLAHRALRGNRDPRHPERRCRGPNYRLHVDGAPHGR", "length": 328 }, "evidence": [ { "id": "Q9W3P7", "url": "https://omabrowser.org/oma/group/Q9W3P7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "M0R8A5-1", "protein_name": "Carbonic anhydrase-related protein 10", "gene_name": "Car10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEIVWEVLFLLQANFIVCISAQQNSPKIHEGWWAYKEVVQGSFVPVPSFWGLVNSAWNLCSVGKRQSPVNIETSHMIFDPFLTPLRINTGGRKVSGTMYNTGRHVSLRLDKEHLVNISGGPMTYSHRLEEIRLHFGSEDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNGLVVVSIFIKVSDSSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPETSSFITYDGSMTIPPCYETASWIIMNKPVYITRMQMHSLRLLSQNQPSQIFLSMSDNFRPVQPLNNRCIRTNINFSLQGKDCPNNRAQKLQYRVNEWLLK", "length": 328 }, "evidence": [ { "id": "HGNC:1369", "url": "https://alliancegenome.org/gene/HGNC:1369#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080815-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080815-2#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-051030-123", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-051030-123#orthology", "database": "AGR" }, { "id": "MGI:1919855", "url": "https://alliancegenome.org/gene/MGI:1919855#orthology", "database": "AGR" }, { "id": "RGD:2322930", "url": "https://alliancegenome.org/gene/RGD:2322930#orthology", "database": "AGR" }, { "id": "FB:FBgn0029962", "url": "https://alliancegenome.org/gene/FB:FBgn0029962#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O70354-1", "protein_name": "Carbonic anhydrase-related protein 11", "gene_name": "Ca11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGGAARLSAPQALVLWAALGAAAHIGPAPDPEDWWSYKENLQGNFVPGPPFWGLVNAAWSLCAVGKRQSPVDVELKRVLYDPFLPPLRLSTGGEKLRGTLYNTGRHVSFLPASRPVVNVSGGPLLYSHRLSELRLLFGARDGAGSEHQINHEGFSAEVQLIHFNQELYGNLSAASRGPNGLAILSLFVNVAGSSNPFLSRLLNRDTITRISYKNDAYFLQDLSLELLFPESFGFITYQGSLSTPPCSETVTWILIDRALNITSLQMHSLRLLSQNPPSQIFQSLSGNGRPLQPLAHRALRGNRDPRHPERRCRGPNYRLHVDGGPHGR", "length": 328 }, "evidence": [ { "id": "HGNC:1370", "url": "https://alliancegenome.org/gene/HGNC:1370#orthology", "database": "AGR" }, { "id": "MGI:1336193", "url": "https://alliancegenome.org/gene/MGI:1336193#orthology", "database": "AGR" }, { "id": "RGD:735155", "url": "https://alliancegenome.org/gene/RGD:735155#orthology", "database": "AGR" }, { "id": "FB:FBgn0029962", "url": "https://alliancegenome.org/gene/FB:FBgn0029962#orthology", "database": "AGR" }, { "id": "Q9W3P7", "url": "https://omabrowser.org/oma/group/Q9W3P7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O75493-1", "protein_name": "Carbonic anhydrase-related protein 11", "gene_name": "CA11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGAAARLSAPRALVLWAALGAAAHIGPAPDPEDWWSYKDNLQGNFVPGPPFWGLVNAAWSLCAVGKRQSPVDVELKRVLYDPFLPPLRLSTGGEKLRGTLYNTGRHVSFLPAPRPVVNVSGGPLLYSHRLSELRLLFGARDGAGSEHQINHQGFSAEVQLIHFNQELYGNFSAASRGPNGLAILSLFVNVASTSNPFLSRLLNRDTITRISYKNDAYFLQDLSLELLFPESFGFITYQGSLSTPPCSETVTWILIDRALNITSLQMHSLRLLSQNPPSQIFQSLSGNSRPLQPLAHRALRGNRDPRHPERRCRGPNYRLHVDGVPHGR", "length": 328 }, "evidence": [ { "id": "HGNC:1370", "url": "https://alliancegenome.org/gene/HGNC:1370#orthology", "database": "AGR" }, { "id": "MGI:1336193", "url": "https://alliancegenome.org/gene/MGI:1336193#orthology", "database": "AGR" }, { "id": "RGD:735155", "url": "https://alliancegenome.org/gene/RGD:735155#orthology", "database": "AGR" }, { "id": "FB:FBgn0029962", "url": "https://alliancegenome.org/gene/FB:FBgn0029962#orthology", "database": "AGR" }, { "id": "Q9W3P7", "url": "https://omabrowser.org/oma/group/Q9W3P7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P61215-1", "protein_name": "Carbonic anhydrase-related protein 10", "gene_name": "Ca10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIVWEVLFLLQANFIVCISAQQNSPKIHEGWWAYKEVVQGSFVPVPSFWGLVNSAWNLCSVGKRQSPVNIETSHMIFDPFLTPLRINTGGRKVSGTMYNTGRHVSLRLDKEHLVNISGGPMTYSHRLEEIRLHFGSEDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNGLVVVSIFIKVSDSSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPETSSFITYDGSMTIPPCYETASWIIMNKPVYITRMQMHSLRLLSQNQPSQIFLSMSDNFRPVQPLNNRCIRTNINFSLQGKDCPNNRAQKLQYRVNEWLLK", "length": 328 }, "evidence": [ { "id": "HGNC:1369", "url": "https://alliancegenome.org/gene/HGNC:1369#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080815-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080815-2#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-051030-123", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-051030-123#orthology", "database": "AGR" }, { "id": "MGI:1919855", "url": "https://alliancegenome.org/gene/MGI:1919855#orthology", "database": "AGR" }, { "id": "RGD:2322930", "url": "https://alliancegenome.org/gene/RGD:2322930#orthology", "database": "AGR" }, { "id": "FB:FBgn0029962", "url": "https://alliancegenome.org/gene/FB:FBgn0029962#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q811X3-1", "protein_name": "Carbonic anhydrase-related protein 11", "gene_name": "Ca11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGGAARLSAPQALVLWAALGAAAHIGPAPDPEDWWSYKENLQGNFVPGPPFWGLVNAAWSLCAVGKRQSPVDVELKRVLYDPFLPPLRLSTGGEKLRGTLYNTGRHVSFLPASRPVVNVSGGPLLYSHRLSELRLLFGARDGAGSEHQINHQGFSAEVQLIHFNQELYGNLSAASRGPNGLAILSLFVNVAGSSNPFLSRLLNRDTITRISYKNDAYFLQDLSLELLFPESFGFITYQGSLSTPPCSETVTWILIDRALNITSLQMHSLRLLSQNPPSQIFQSLSGNGRPLQPLAHRALRGNRDPRHPERRCRGPNYRLHVDGGPHGR", "length": 328 }, "evidence": [ { "id": "HGNC:1370", "url": "https://alliancegenome.org/gene/HGNC:1370#orthology", "database": "AGR" }, { "id": "MGI:1336193", "url": "https://alliancegenome.org/gene/MGI:1336193#orthology", "database": "AGR" }, { "id": "RGD:735155", "url": "https://alliancegenome.org/gene/RGD:735155#orthology", "database": "AGR" }, { "id": "FB:FBgn0029962", "url": "https://alliancegenome.org/gene/FB:FBgn0029962#orthology", "database": "AGR" }, { "id": "Q9W3P7", "url": "https://omabrowser.org/oma/group/Q9W3P7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9NS85-1", "protein_name": "Carbonic anhydrase-related protein 10", "gene_name": "CA10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEIVWEVLFLLQANFIVCISAQQNSPKIHEGWWAYKEVVQGSFVPVPSFWGLVNSAWNLCSVGKRQSPVNIETSHMIFDPFLTPLRINTGGRKVSGTMYNTGRHVSLRLDKEHLVNISGGPMTYSHRLEEIRLHFGSEDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNGLVVVSIFIKVSDSSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPETSSFITYDGSMTIPPCYETASWIIMNKPVYITRMQMHSLRLLSQNQPSQIFLSMSDNFRPVQPLNNRCIRTNINFSLQGKDCPNNRAQKLQYRVNEWLLK", "length": 328 }, "evidence": [ { "id": "HGNC:1369", "url": "https://alliancegenome.org/gene/HGNC:1369#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080815-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080815-2#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-051030-123", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-051030-123#orthology", "database": "AGR" }, { "id": "MGI:1919855", "url": "https://alliancegenome.org/gene/MGI:1919855#orthology", "database": "AGR" }, { "id": "RGD:2322930", "url": "https://alliancegenome.org/gene/RGD:2322930#orthology", "database": "AGR" }, { "id": "FB:FBgn0029962", "url": "https://alliancegenome.org/gene/FB:FBgn0029962#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W316-1", "protein_name": "4.2.1.-", "gene_name": "CARPB", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MELLQALCCTLLLLLARMQVLLAVSWEDWWTYDGISGPAFWGLINPEWSLCNKGRRQSPVNLEPQRLLFDPNLRPMHIDKHRISGLITNTGHSVIFTAGNDTVANYDGMQTPVNISGGPLSYRYRFHEIHMHYGLNDQFGSEHSVEGYTFPAEIQIFGYNSQLYANFSDALNRAQGIVGVSILLQLGDLSNAELRMLTDQLERIRYGGDEAFVKRLSIRGLLPDTDHYMTYDGSTTAPACHETVTWVVLNKPIYITKQQLHALRRLMQGSPDHPKAPLGNNYRPPQPLLHRPIRTNIDFKTTKSNGKAACPTMYREVYYKATSWKQN", "length": 327 }, "evidence": [ { "id": "HGNC:1370", "url": "https://alliancegenome.org/gene/HGNC:1370#orthology", "database": "AGR" }, { "id": "HGNC:1369", "url": "https://alliancegenome.org/gene/HGNC:1369#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080815-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080815-2#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-051030-123", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-051030-123#orthology", "database": "AGR" }, { "id": "MGI:1919855", "url": "https://alliancegenome.org/gene/MGI:1919855#orthology", "database": "AGR" }, { "id": "MGI:1336193", "url": "https://alliancegenome.org/gene/MGI:1336193#orthology", "database": "AGR" }, { "id": "RGD:735155", "url": "https://alliancegenome.org/gene/RGD:735155#orthology", "database": "AGR" }, { "id": "RGD:2322930", "url": "https://alliancegenome.org/gene/RGD:2322930#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q9W3P7", "url": "https://www.uniprot.org/uniprotkb/Q9W3P7" } ], "pmid": "" }, { "name": "hydro-lyase activity", "id": "GO:0016836", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016836", "evidence": [ { "database": "UniProtKB", "id": "Q9W3P7", "url": "https://www.uniprot.org/uniprotkb/Q9W3P7" } ], "pmid": "" }, { "name": "carbonate dehydratase activity", "id": "GO:0004089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004089", "evidence": [ { "database": "UniProtKB", "id": "Q9W3P7", "url": "https://www.uniprot.org/uniprotkb/Q9W3P7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 116, "end_pos": 118, "annotation": "n_glycosylation_sequon" }, { "start_pos": 168, "end_pos": 170, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9W3P7", "database": 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"https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3R0", "url": "https://www.uniprot.org/uniprotkb/Q9W3R0" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3R0", "url": "https://www.uniprot.org/uniprotkb/Q9W3R0" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W3R0", "url": "https://www.uniprot.org/uniprotkb/Q9W3R0" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W3R0", "url": "https://www.uniprot.org/uniprotkb/Q9W3R0" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W3R0", "url": "https://www.uniprot.org/uniprotkb/Q9W3R0" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3R0", "url": "https://www.uniprot.org/uniprotkb/Q9W3R0" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3R0", "url": "https://www.uniprot.org/uniprotkb/Q9W3R0" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W3R0", "url": "https://www.uniprot.org/uniprotkb/Q9W3R0" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W3R0", "url": "https://www.uniprot.org/uniprotkb/Q9W3R0" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG9657", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG9657", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6ARH5-1", "protein_name": "Solute carrier family 5 member 12", "gene_name": "Slc5a12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVKSFEAWDYVVFAALFVISSGIGVFFAIKERKKTTSREFLVGGRQMSFAPVALSLTASFMSAVTVLGTPAEVYRFGASFLIFLISYAFVVFFTSELFLPVFYRSGITSTYEYLQLRFNKPVRYAATIIYILQTILYTGVVVYAPALALNQVTGFNLWASVFATGIVCTFYCSLGGLKAVVWTDAFQMVVMIVGFLTVLIQGSNHVGGFDNVLEQARNGSRLDIVDFDVDPLRRHTFWTIAVGGTFTWLGIYGVNQSTIQRCISCKTEKHAKLALYFNLLGLWIIVVCAVFCGLIMYAYYKDCDPWTSGAILAPDQLMPYFVMEIFATMPGLPGLFVACAFSGTLSTVAASINALATVTFEDFVKSCFPHLSDTLSTWISKGLCLLFGIICTSMAVLASLMGSVVQGALGGLLTGITLSFWVGIGAFVYPAPDSKTLPLPLSTEFCVQQNKTTTEAYQLSSRPVLADTWYSLSYLYFSAVGCLGCIAAGIIISFLTGRQRGKDVDPLLIRPVCNLFCFWSKKYKTLCWCGVRHDQETEQDYLDSGSAWKQGVESGLQNGLKQDTLSQIPAYNPKDKSYPKSVQEKTTYF", "length": 590 }, "evidence": [ { "id": "MGI:2138890", "url": "https://alliancegenome.org/gene/MGI:2138890#orthology", "database": "AGR" }, { "id": "FB:FBgn0029950", "url": "https://alliancegenome.org/gene/FB:FBgn0029950#orthology", "database": "AGR" }, { "id": "RGD:1311652", "url": "https://alliancegenome.org/gene/RGD:1311652#orthology", "database": "AGR" }, { "id": "HGNC:28750", "url": "https://alliancegenome.org/gene/HGNC:28750#orthology", "database": "AGR" }, { "id": "SGD:S000001008", "url": "https://alliancegenome.org/gene/SGD:S000001008#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3Z9E5-1", "protein_name": "Sodium-coupled monocarboxylate transporter 1", "gene_name": "Slc5a8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDASRDIGSFVVWDYVVFAGMLLISAAIGIYYAFAGGGQQTSKDFLMGGRSMSAVPVALSLTASFMSAVTVLGTPAEVYRFGAIFSIFGVTYFFVVVISAEVFLPVFYRLGITSTYEYLELRFNRFIRLCGTVLFIVQTILYTGIVIYAPALALNQVTGFDLWGAVVATGVVCTFYCTLGGLKAVVWTDVFQVGIMVAGFASVIIQASITQGGINTILSDASNGGRLNFWNFNPNPLQRHTFWTIIVGGTFTWTTIYGVNQSQVQRYISCKSRLHAKLSLYVNLVGLWVILICSVFCGLALYSRYHDCDPWTSKKVSEVDQLMPYLVLDILKNYPGVPGLFVACAYSGTLSTVSSSINALAAVTVEDLIKPRFKSLSEKSLSWISQGMSVLYGALCIGMAAVASLMGALLQAALSIFGMVGGPLLGLFSLGILVPFANSVGAFAGLLAGFAVSLWVGIGAQLYPPLPERTLPLSLETHGCNSTHNGTDWMSTTEMPFSTSAFQIHDVERSALMDNWYSLSYLYFSTIGTLTTLLVGILISLATGGRKQNLDPRFLLTKQDFLSNFDVFKKKTHVLNYKMHPVEDGGTDNPAFNHVELNFPDHSGKINGTRL", "length": 611 }, "evidence": [ { "id": "RGD:1564146", "url": "https://alliancegenome.org/gene/RGD:1564146#orthology", "database": "AGR" }, { "id": "FB:FBgn0029950", "url": "https://alliancegenome.org/gene/FB:FBgn0029950#orthology", "database": "AGR" }, { "id": "HGNC:19119", "url": "https://alliancegenome.org/gene/HGNC:19119#orthology", "database": "AGR" }, { "id": "SGD:S000001008", "url": "https://alliancegenome.org/gene/SGD:S000001008#orthology", "database": "AGR" }, { "id": "MGI:2384916", "url": "https://alliancegenome.org/gene/MGI:2384916#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P33413-1", "protein_name": "Urea active transporter", "gene_name": "DUR3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MGEFKPPLPQGAGYAIVLGLGAVFAGMMVLTTYLLKRYQKEIITAEEFTTAGRSVKTGLVAAAVVSSWIWCSTLLTSSTKEYADGIFGGYAYAAGACFQIIAFAILAIKTKQMAPNAHTYLELVRTRYGKIGHGCYLFYAIATNILVTSMLLTSGSAVFSDLTGMNTIASCFLLPVGVVVYTLFGGIKATFLTDYMHTCVIIIIVLVFAFKVYATSDVLGSPGKVYDLVREAAKRHPVDGNYQGEYMTMTSKSAGILLIINLIGNFGTVFLDNGYWNKAISASPAASLKAYAIGGLAWFAVPSLISLTMGLACLAVETSPNFPTYPDPLTSFQANSGLVLPAAAIAIMGKGGAVASLLMIFMAVTSAMSAELIAVSSVFTYDIYREYIDPRASGKKLIYTSHVACIFFGLAMSGFSVGLYYGGISMGYIYEMMGIIISSAVLPVVLTLCSKDMNLVAAVVSPILGTGLAIMSWLVCTKSLYKELTVDTTFMDYPMLTGNLVALLSPAIFIPILTYVFKPQNFDWEKMKDITRVDETAELVQADPDIQLYDAEANDKEQEEETNSLVSDSEKNDVRVNNEKLIEPNLGVVISNAIFQEDDTQLQNELDEEQRELARGLKIAYFLCVFFALAFLVVWPMPMYGSKYIFSKKFFTGWVVVMIIWLFFSAFAVCIYPLWEGRHGIYTTLRGLYWDLSGQTYKLREWQNSNPQDLHVVTSQISARAHRQSSHFGQVDEII", "length": 735 }, "evidence": [ { "id": "RGD:1564146", "url": "https://alliancegenome.org/gene/RGD:1564146#orthology", "database": "AGR" }, { "id": "MGI:2138890", "url": "https://alliancegenome.org/gene/MGI:2138890#orthology", "database": "AGR" }, { "id": "HGNC:11040", "url": "https://alliancegenome.org/gene/HGNC:11040#orthology", "database": "AGR" }, { "id": "FB:FBgn0029950", "url": "https://alliancegenome.org/gene/FB:FBgn0029950#orthology", "database": "AGR" }, { "id": "RGD:69267", "url": "https://alliancegenome.org/gene/RGD:69267#orthology", "database": "AGR" }, { "id": "RGD:1311652", "url": "https://alliancegenome.org/gene/RGD:1311652#orthology", "database": "AGR" }, { "id": "SGD:S000001008", "url": "https://alliancegenome.org/gene/SGD:S000001008#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P83740-1", "protein_name": "Putative sodium-dependent multivitamin transporter", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MATLGAWDYTILAVVLIISVAIGIYYRFVGGKQSTTTEYLLADRSMNVAPVAFSLMASFMSAVTILGVSMENYQYGTMFVVINLSYVLSTPVAAYLIIPVFYRLKTASVYEYLELRFGYATRLAASLSFSLQMVLYMGIVVYAPALALEAVTGLSQVFSIVIVGVVCTFYATLGGMKAVLITDIYQSLLMFAAVFSVIICAWVKAGSLEVIWRVAQENGRINLTNFSVDPTERHTWFTQILGGCATYLAIYGVNQTQVQRLMAVKSLSAARAALWWCLPILCLLSLSTCFSGLCIYWYYRDCDPLLEGRVNSRDQVMPLFVVDTMGEYTGLAGLFVSGIFCASLSTISSIISSLAAVTLEDYLKPLVSCCAKRTLTDRQTLWYSKLLSLFFGALCIGMAFMAGSIGGLLQAALSIFGIIGGPLLGLFTLGMYVTKANEKGAIGGLLISLAFCFWIGFGQPKPPLVSLDMSTAGCPVDRSFARDIFLKTVIAVAEEEHYFYLYRISYMWYAALGFLITFFGGWLLSWLFALLKWDNNRRIYQDADCTLIKHDLFVPPIAKRLQRRQMPLLVVTGTSSEIGGITTESATAPPRLDEIEWEKHKAVA", "length": 604 }, "evidence": [ { "id": "RGD:1564146", "url": "https://alliancegenome.org/gene/RGD:1564146#orthology", "database": "AGR" }, { "id": "MGI:2138890", "url": "https://alliancegenome.org/gene/MGI:2138890#orthology", "database": "AGR" }, { "id": "HGNC:11040", "url": "https://alliancegenome.org/gene/HGNC:11040#orthology", "database": "AGR" }, { "id": "RGD:69267", "url": "https://alliancegenome.org/gene/RGD:69267#orthology", "database": "AGR" }, { "id": "RGD:1311652", "url": "https://alliancegenome.org/gene/RGD:1311652#orthology", "database": "AGR" }, { "id": "HGNC:19119", "url": "https://alliancegenome.org/gene/HGNC:19119#orthology", "database": "AGR" }, { "id": "HGNC:28750", "url": "https://alliancegenome.org/gene/HGNC:28750#orthology", "database": "AGR" }, { "id": "MGI:2149330", "url": "https://alliancegenome.org/gene/MGI:2149330#orthology", "database": "AGR" }, { "id": "MGI:2384916", "url": "https://alliancegenome.org/gene/MGI:2384916#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P91659-1", "protein_name": "Sodium-coupled monocarboxylate transporter 2", "gene_name": "Dmel\\CG2187", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSTTTTTTTTMASAVSSASQDLRFGLTDYFVFVIMLGASAGIGVYFGFFSKSKNTTEEYLRGGKKMQTLPIAISLVASQLSGIAIMSIPAESYTYGFNYIFVVLAMLVVIPILIYIIVPVFYENNVSNCYEYLEMRFNKRTRQLVTFFFVTNSFLMLPVYMFIPSLAFAQVTGMNIHLINVMVSSICIFYTMLGGIKAVVWTDVVQGAIMLLSVVAVGVLGTIRSGGMFTVMERASDGGRFNFDFGLDPRIRMTFWGATMGGIFMWTGHIGLNQSCVQRIVSLPSYSHAKKSLIVSGLGFLIISFFNTISGIIMFARYYGCDPMLAGLVSKPDKMMPFFVQDIMGHLAGMPGVFISCVFSAALSSLSATLNSLAGVVYFDYIKPRIRHTEARANWAMKLIVVVMGGYCILGGFMVQNFNSILQTVVTITGINTGAVVGVFLLGMFVPRCNAKTAVTSIIVSVVAMVWIIANGQMNFKSGLIKYEVLPNSLDQCEARGLYMIAEAINKTDFTPVTMKPPSGAPVTTAFHSDRDFSLYDISFYWYKVLGSALVFLCAIPLSYIWRPDENEKQNPKLYSPFVRKFLSLPVTDQDLEEVPLRGSKVAATPDLRIEPTEKEKQTVTEP", "length": 623 }, "evidence": [ { "id": "RGD:1564146", "url": "https://alliancegenome.org/gene/RGD:1564146#orthology", "database": "AGR" }, { "id": "MGI:2138890", "url": "https://alliancegenome.org/gene/MGI:2138890#orthology", "database": "AGR" }, { "id": "HGNC:11040", "url": "https://alliancegenome.org/gene/HGNC:11040#orthology", "database": "AGR" }, { "id": "RGD:69267", "url": "https://alliancegenome.org/gene/RGD:69267#orthology", "database": "AGR" }, { "id": "RGD:1311652", "url": "https://alliancegenome.org/gene/RGD:1311652#orthology", "database": "AGR" }, { "id": "HGNC:19119", "url": "https://alliancegenome.org/gene/HGNC:19119#orthology", "database": "AGR" }, { "id": "HGNC:28750", "url": "https://alliancegenome.org/gene/HGNC:28750#orthology", "database": "AGR" }, { "id": "SGD:S000001008", "url": "https://alliancegenome.org/gene/SGD:S000001008#orthology", "database": "AGR" }, { "id": "MGI:2149330", "url": "https://alliancegenome.org/gene/MGI:2149330#orthology", "database": "AGR" }, { "id": "MGI:2384916", "url": "https://alliancegenome.org/gene/MGI:2384916#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q1EHB4-1", "protein_name": "Sodium-coupled monocarboxylate transporter 2", "gene_name": "SLC5A12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEVKNFAVWDYVVFAALFFISSGIGVFFAIKERKKATSREFLVGGRQMSFGPVGLSLTASFMSAVTVLGTPSEVYRFGASFLVFFIAYLFVILLTSELFLPVFYRSGITSTYEYLQLRFNKPVRYAATVIYIVQTILYTGVVVYAPALALNQVTGFDLWGSVFATGIVCTFYCTLGGLKAVVWTDAFQMVVMIVGFLTVLIQGSTHAGGFHNVLEQSTNGSRLHIFDFDVDPLRRHTFWTITVGGTFTWLGIYGVNQSTIQRCISCKTEKHAKLALYFNLLGLWIILVCAVFSGLIMYSHFKDCDPWTSGIISAPDQLMPYFVMEIFATMPGLPGLFVACAFSGTLSTVASSINALATVTFEDFVKSCFPHLSDKLSTWISKGLCLLFGVMCTSMAVAASVMGGVVQASLSIHGMCGGPMLGLFSLGIVFPFVNWKGALGGLLTGITLSFWVAIGAFIYPAPASKTWPLPLSTDQCIKSNVTATGPPVLSSRPGIADTWYSISYLYYSAVGCLGCIVAGVIISLITGRQRGEDIQPLLIRPVCNLFCFWSKKYKTLCWCGVQHDSGTEQENLENGSARKQGAESVLQNGLRRESLVHVPGYDPKDKSYNNMAFETTHF", "length": 618 }, "evidence": [ { "id": "MGI:2138890", "url": "https://alliancegenome.org/gene/MGI:2138890#orthology", "database": "AGR" }, { "id": "FB:FBgn0029950", "url": "https://alliancegenome.org/gene/FB:FBgn0029950#orthology", "database": "AGR" }, { "id": "RGD:1311652", "url": "https://alliancegenome.org/gene/RGD:1311652#orthology", "database": "AGR" }, { "id": "HGNC:28750", "url": "https://alliancegenome.org/gene/HGNC:28750#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3ZMH1-1", "protein_name": "Sodium-coupled monocarboxylate transporter 1", "gene_name": "slc5a8", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPGSGGPVATFSVWDYVVFAGLILVAAGIGLFQSFRGRKEASSDEFLLGGRQMTAVPVALSLTASFMSGITVIGTPAEAYLYGTPFWLFFISYAIMSTISAEIFVPLFYRLNITSTYEYLEMRYNKLIRVIGTSMYIIQTALYTGMVIFAPALALNQITGLDLWGVLVATGAVCIIYCTLGGLKAVIWTDVFQMIIMLGGFVAVIARGAVLQGGLGRVWNDSFYGGRLETFSFDPDPLRRHSFWTIVVGGSLMWASMYSINQSQVQRYISCRTMTHAKLSLYVNMVGLWVTVSLAMMSGLTMYSIYKDCDPFTNKDVGATDQLLPYLVMDILADFPGLPGLFVAAAYSGTLSTVSSSINALVAVTVEDFMKPAWPSLTERQLSWINMGMSVFYGAVCIGMAGVASMMGNILQAALSIFGMISGPLLGLYMLGMFFRCANSTGGLAGLASGLAITLWVGIGAQLYPPLPEKTLRLPLSVEGCVALNTSETTTMTPFSTVLQTTTPQPRPALADNWYSLSYLYFSPVGIVVTMIIALIVSAISGGCKQKKVRPELFISKSDLICFRCKKSDSEVSDLIETKPKDNQGLDSPVFYDNEIVLKEKDQQEKITKL", "length": 610 }, "evidence": [ { "id": "RGD:1564146", "url": "https://alliancegenome.org/gene/RGD:1564146#orthology", "database": "AGR" }, { "id": "HGNC:19119", "url": "https://alliancegenome.org/gene/HGNC:19119#orthology", "database": "AGR" }, { "id": "MGI:2384916", "url": "https://alliancegenome.org/gene/MGI:2384916#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q49B93-1", "protein_name": "Sodium-coupled monocarboxylate transporter 2", "gene_name": "Slc5a12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRVKNFEAWDYVVFAGLFVISSGIGVFFAIKERKKTTSREFLVGGRQMSFGPVALSLTASFMSAVTVLGTPAEVYRFGASFFLFLISYVFVVFFTSELFLPVFYRSGITSTYEYLQLRFNKPVRYAATIIYIVQTILYTGVVVYAPALALNQVTGFNLWASVFATGIVCTFYCSLGGLKAVVWTDAFQMVVMIVGFLTVLIQGSNHVGGFNNVLEKAGNGSRLHIVDFDVDPLRRHTFWTITIGGTFTWLGVYGVNQSTIQRCISCKTEKHAKLALYFNLLGLWIIVACAVFSGLIMYSHFKDCDPWTSGVISAPDQLMPYFVMEIFATMPGLPGLFVACAFSGTLSTVAASINALATVTFEDFVKSCFPHLSDKLSTWISKGLCILFGIMCTSMAVVASLMGSVVQAALSIHGMCGGPMLGLFTLGLVFPFVNWKGALGGLLTGITLSFWVAIGSFIYPAPESKTLPLPLSTEHCVELNITTTVAPQISSRPVLADTWYSLSYLYFSAVGCLGCIAAGIIISFLTGKQRGKDIDPLLIRPVCNLFCFWSKKYKTLCWCGVQHDRETEQDYLDSGSAWKQGVESGLQNGLKQDTLAQIPGYNPKEKSYSNSVPEKTTYF", "length": 619 }, "evidence": [ { "id": "MGI:2138890", "url": "https://alliancegenome.org/gene/MGI:2138890#orthology", "database": "AGR" }, { "id": "FB:FBgn0029950", "url": "https://alliancegenome.org/gene/FB:FBgn0029950#orthology", "database": "AGR" }, { "id": "RGD:1311652", "url": "https://alliancegenome.org/gene/RGD:1311652#orthology", "database": "AGR" }, { "id": "HGNC:28750", "url": "https://alliancegenome.org/gene/HGNC:28750#orthology", "database": "AGR" }, { "id": "SGD:S000001008", "url": "https://alliancegenome.org/gene/SGD:S000001008#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5SWY8-1", "protein_name": "Sodium/mannose cotransporter SLC5A10", "gene_name": "Slc5a10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGNSTGDAHVPGSQLSVTDIIVISVYFALNVAVGIWSACRANKNTVSGYFLAGRDMAWWPIGASLFASSEGSGLFVGLAGSGAAGGLAVAGFEWNATYVLLALAWVFVPIYISSEIVTLPEYIQKRFGGQRIRTYLSVLSLMLSVFTKISIDLYAGALFVHICLGWNFYLSTILTLAITALYTIAGGLATVIYTDALQTIIMVVGAVILAVKAFNQIGGYEQLEAAYAQAIPSRTIPNTTCHLPRADAMHMFRDPSTGDLPWTGMTFGLTIMATWYWCTDQVIVQRSLSARNLNHAKAGSILASYLKMLPMGLMIMPGMISRVLFPDDVGCVVPSECLRACGAEIGCSNIAYPKLVMELMPIGLRGLMIAVMMAALLSSLTSIFNSSSTLFTMDIWRQLRPSAGERELLLVGRLVIVVLIGVSVAWIPVLQGSNSGQLFIYMQSVTSSLAPPVTAIFILGIFWRRANEQGAFWGLMAGLVVGALRLVLEFLYPEPPCGQIDTRPAPLRSLHYLHFAIALFLLTCAVMAAGSLLSPPPQQRQIENLTWWTLAPNWSLGTKTGDGQTPQKRAFWARVCNVNAIFLMCVNIFFYAYFA", "length": 596 }, "evidence": [ { "id": "SGD:S000001008", "url": "https://alliancegenome.org/gene/SGD:S000001008#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q63008-1", "protein_name": "Sodium/iodide cotransporter", "gene_name": "Slc5a5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGAEAGARATFGAWDYGVFATMLLVSTGIGLWVGLARGGQRSADDFFTGGRQLAAVPVGLSLAASFMSAVQVLGVPAEAARYGLKFLWMCAGQLLNSLLTAFLFLPIFYRLGLTSTYQYLELRFSRAVRLCGTLQYLVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTLYTTVGGMKAVVWTDVFQVVVMLVGFWVILARGVILLGGPRNVLSLAQNHSRINLMDFDPDPRSRYTFWTFIVGGTLVWLSMYGVNQAQVQRYVACHTEGKAKLALLVNQLGLFLIVASAACCGIVMFVYYKDCDPLLTGRISAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSINAMAAVTVEDLIKPRMPGLAPRKLVFISKGLSFIYGSACLTVAALSSLLGGGVLQGSFTVMGVISGPLLGAFTLGMLLPACNTPGVLSGLAAGLAVSLWVAVGATLYPPGEQTMGVLPTSAAGCTNDSVLLGPPGATNASNGIPSSGMDTGRPALADTFYAISYLYYGALGTLTTMLCGALISYLTGPTKRSSLGPGLLWWDLARQTASVAPKEDTATLEESLVKGPEDIPAVTKKPPGLKPGAETHPLYLGHDVETNL", "length": 618 }, "evidence": [ { "id": "HGNC:11040", "url": "https://alliancegenome.org/gene/HGNC:11040#orthology", "database": "AGR" }, { "id": "FB:FBgn0029950", "url": "https://alliancegenome.org/gene/FB:FBgn0029950#orthology", "database": "AGR" }, { "id": "RGD:69267", "url": "https://alliancegenome.org/gene/RGD:69267#orthology", "database": "AGR" }, { "id": "SGD:S000001008", "url": "https://alliancegenome.org/gene/SGD:S000001008#orthology", "database": "AGR" }, { "id": "MGI:2149330", "url": "https://alliancegenome.org/gene/MGI:2149330#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7T384-1", "protein_name": "Sodium-coupled monocarboxylate transporter 2", "gene_name": "slc5a12", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "METVGRFQAGDYVVFACLFVVSSGIGVFFAIKERNKAPSKEFLVGGRQMSCGPVALSLTASFMSAVTVIGAPADVYRFGASYVIFGVAYTFVVFFTAELFLPVFYRSGITSTYEYLELRFCKLVRVAATLIYIIQTILYTGVVVYAPALALNQVTGFDLWGSIFATGIVCTFYCTLGGLKAVVWTDAFQMVVMVVGFLTVLIQGSSRAGGIENVWSTSRTGGRLQVFDFDVSPLRRHTFWTLSVGGTFTWLGIYGVNQSTIQRCISCKTEGHARWALYLNLLGLWIILFCAVVSGLIMYSYYSHCDPWSSGLISAPDQLMPYFVMEILGAFPGLPGLFVACAFSGTLSTVAASINALATVMYEDFVSQCFPDLSNRAASWISKALCVAFGVACTTMAVAASYMGGIVQAALSIHGMCGGPVLGLFSLGILFPFTNLKGAVGGLIVGISLSFWVGVGAFIYPAPSNNTHALELNTAGCNITAAAFEPTSATVTQLTSDRNWLADSWYSMSYLYYSAVGFIGTVAAGLLITLLTGPMDPKLLKPGMTRSVKEVMCFCTEKFTEADLGEGKEDVGDFGKAWEKHPDQGCTLRMDEKFRCSCDNQQENGNTNAGFDHNETSIVQKKL", "length": 623 }, "evidence": [ { "id": "MGI:2138890", "url": "https://alliancegenome.org/gene/MGI:2138890#orthology", "database": "AGR" }, { "id": "RGD:1311652", "url": "https://alliancegenome.org/gene/RGD:1311652#orthology", "database": "AGR" }, { "id": "HGNC:28750", "url": "https://alliancegenome.org/gene/HGNC:28750#orthology", "database": "AGR" }, { "id": "SGD:S000001008", "url": "https://alliancegenome.org/gene/SGD:S000001008#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8BYF6-1", "protein_name": "Sodium-coupled monocarboxylate transporter 1", "gene_name": "Slc5a8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDASRDIGSFVVWDYVVFAGMLLISAAIGIYYAFAGGGQQTSKDFLMGGRSMSAVPVALSLTASFMSAVTVLGTPAEVYRFGAIFSIFVITYFFVVVISAEVFLPVFYRLGITSTYEYLELRFNRCIRLCGTILFIVQTILYTGIVIYAPALALNQVTGFDLWGAVVATGVVCTFYCTLGGLKAVVWTDVFQVGIMVAGFASVIIQASITQHGINKILSDAFNGGRLNFWNFDPNPLQRHTFWTIVIGGTFTWTTIYGVNQSQVQRYISCKSRLHAKLSLYVNLVGLWVILTCSIFCGLALYSRYRECDPWTSKKVSAIDQLMPYLVLDILKNYPGVPGLFVACAYSGTLSTVSSSINALAAVTVEDLIKPRFKSLSEKSLSWISQGMSVLYGALCIGMAALASLMGALLQAALSIFGMVGGPLLGLFSLGILVPFANSIGALTGLLAGFAISLWVGIGAQLYPPLPERTLPLPLETYGCNITHNGSDWMSTTEMPFSTSAFQIHNAERTPLMDNWYSLSYLYFSTIGTLTTLFVGILISLSTGGRKQNLDPRFLLTKQDFLSNFDVFKKRNHVLNYKLHPVEVGGTDNPAFNHVELNFTDHSGKINGTRL", "length": 611 }, "evidence": [ { "id": "RGD:1564146", "url": "https://alliancegenome.org/gene/RGD:1564146#orthology", "database": "AGR" }, { "id": "FB:FBgn0029950", "url": "https://alliancegenome.org/gene/FB:FBgn0029950#orthology", "database": "AGR" }, { "id": "HGNC:19119", "url": "https://alliancegenome.org/gene/HGNC:19119#orthology", "database": "AGR" }, { "id": "MGI:2384916", "url": "https://alliancegenome.org/gene/MGI:2384916#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IN99-1", "protein_name": "Sodium-coupled monocarboxylate transporter 2", "gene_name": "Dmel\\CG31262", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDNYRFGTVDYLVLVAMTLLSTGTGIYFGALKKKHKNKKSVSEDNRRTNFGSEKIDEYLMGSRNMKVIPVSITLYRVTSIIGTPSEIYHYGTQYYLIIVAIILQGIAFSYVYLPVYSALQIGSAYEYLGLRFNSIIRTTASFMYVFGILTYLPFIVYVPALSLSQVSGLNTHLIGLVIILACVTYTFMGGLKAVVHTDVWQVAVMFLSLVAVAFLAIYYSNGLVAVFDDAEQGGRLMLANTNPSPYVRHTVWSVLIGGFSFWTSVNAGGQHMVQRYMSLPSLKKSRQASFIFTIGVSIFIALCCFMGLLLFSKYKDCDPRSAGMILNDDQLLPLFVVQSVGHIYGMPGLFIAGIFGAGLSSLSSCFNTVSMVFLEDIVRGFFKMEPSERQSTILIKTCIIFQGILAFLIVFLLQHLRGILSVCNSISSITAGTSFGVFTLGMLFPWANTIGTAVGGLSSVLLAGWISFGSQIAAASGQLKSGMLPVSVKECVGNVTLPEDPWVDQDQVFPLYRLSYHWVSPIGVVTAVVVGALVSLITKPADIKTLHAELISPVIHRFLPRECFRGRNLNERTEESLIQ", "length": 579 }, "evidence": [ { "id": "RGD:1564146", "url": "https://alliancegenome.org/gene/RGD:1564146#orthology", "database": "AGR" }, { "id": "MGI:2138890", "url": "https://alliancegenome.org/gene/MGI:2138890#orthology", "database": "AGR" }, { "id": "HGNC:11040", "url": "https://alliancegenome.org/gene/HGNC:11040#orthology", "database": "AGR" }, { "id": "RGD:69267", "url": "https://alliancegenome.org/gene/RGD:69267#orthology", "database": "AGR" }, { "id": "RGD:1311652", "url": "https://alliancegenome.org/gene/RGD:1311652#orthology", "database": "AGR" }, { "id": "HGNC:19119", "url": "https://alliancegenome.org/gene/HGNC:19119#orthology", "database": "AGR" }, { "id": "HGNC:28750", "url": "https://alliancegenome.org/gene/HGNC:28750#orthology", "database": "AGR" }, { "id": "SGD:S000001008", "url": "https://alliancegenome.org/gene/SGD:S000001008#orthology", "database": "AGR" }, { "id": "MGI:2149330", "url": "https://alliancegenome.org/gene/MGI:2149330#orthology", "database": "AGR" }, { "id": "MGI:2384916", "url": "https://alliancegenome.org/gene/MGI:2384916#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8IPY0-1", "protein_name": "Sodium-coupled monocarboxylate transporter 2", "gene_name": "CG31668-PB", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDTYRFGTVDYAVFLGVTILSIAIGLYFGFIRKSRNGPKTTTPTNEAPERRHQNFGSKKMNDYMMGSRNLRVFPVGMSLIASCISAVAIIGTPSEIYNYGTQYCFIVIALVLQGLAVSYIYLPVFSALQVTSSYEYLEMRFHSAIRSIVSIIFILDVVLYLPFLAYLPALALNQVSGMNMYLIEAFIIVICVIYTVLGGLKAVVHTDIWQVVIMFASVLTIVVLATCYIDDQADFLEGLVRGGRLIFSETNPSPFARHTVWSVVIGNTFYWTSLNAVHQTVVHRYMSLPTLKMARASIAFLVVGAAFFISLLCYLGLLIFHAYRDCDPLSAGLIMNDDQLVPLFVVNSLGHVYGMPGLFIAGIFGASLSSLSVYLNSTSLVILQDLVRGCFKMELGEWASTIVVKGSIVVLGLLAFAMVFVLEKVSGVLSISVSLAAIAASSTFGIFTVGMLVPWANTVGTAVGGIASVLLTGWISFGSQFAAASGQLGSQRLPVSVEGCLANASVAENAWVAEEEVFPLYRLSYHWISPIGVLTVVVVGSLVSLVTKPTDIKSLDSDLITPVIHRFLPKECFEQGNAEENSVKDNPLLF", "length": 590 }, "evidence": [ { "id": "RGD:1564146", "url": "https://alliancegenome.org/gene/RGD:1564146#orthology", "database": "AGR" }, { "id": "MGI:2138890", "url": "https://alliancegenome.org/gene/MGI:2138890#orthology", "database": "AGR" }, { "id": "HGNC:11040", "url": "https://alliancegenome.org/gene/HGNC:11040#orthology", "database": "AGR" }, { "id": "RGD:69267", "url": "https://alliancegenome.org/gene/RGD:69267#orthology", "database": "AGR" }, { "id": "RGD:1311652", "url": "https://alliancegenome.org/gene/RGD:1311652#orthology", "database": "AGR" }, { "id": "HGNC:19119", "url": "https://alliancegenome.org/gene/HGNC:19119#orthology", "database": "AGR" }, { "id": "HGNC:28750", "url": "https://alliancegenome.org/gene/HGNC:28750#orthology", "database": "AGR" }, { "id": "SGD:S000001008", "url": "https://alliancegenome.org/gene/SGD:S000001008#orthology", "database": "AGR" }, { "id": "MGI:2149330", "url": "https://alliancegenome.org/gene/MGI:2149330#orthology", "database": "AGR" }, { "id": "MGI:2384916", "url": "https://alliancegenome.org/gene/MGI:2384916#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8N695-1", "protein_name": "Sodium-coupled monocarboxylate transporter 1", "gene_name": "SLC5A8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDTPRGIGTFVVWDYVVFAGMLVISAAIGIYYAFAGGGQQTSKDFLMGGRRMTAVPVALSLTASFMSAVTVLGTPSEVYRFGAIFSIFAFTYFFVVVISAEVFLPVFYKLGITSTYEYLELRFNKCVRLCGTVLFIVQTILYTGIVIYAPALALNQVTGFDLWGAVVATGVVCTFYCTLGGLKAVIWTDVFQVGIMVAGFASVIIQAVVMQGGISTILNDAYDGGRLNFWNFNPNPLQRHTFWTIIIGGTFTWTSIYGVNQSQVQRYISCKSRFQAKLSLYINLVGLWAILTCSVFCGLALYSRYHDCDPWTAKKVSAPDQLMPYLVLDILQDYPGLPGLFVACAYSGTLSTVSSSINALAAVTVEDLIKPYFRSLSERSLSWISQGMSVVYGALCIGMAALASLMGALLQAALSVFGMVGGPLMGLFALGILVPFANSIGALVGLMAGFAISLWVGIGAQIYPPLPERTLPLHLDIQGCNSTYNETNLMTTTEMPFTTSVFQIYNVQRTPLMDNWYSLSYLYFSTVGTLVTLLVGILVSLSTGGRKQNLDPRYILTKEDFLSNFDIFKKKKHVLSYKSHPVEDGGTDNPAFNHIELNSDQSGKSNGTRL", "length": 610 }, "evidence": [ { "id": "RGD:1564146", "url": "https://alliancegenome.org/gene/RGD:1564146#orthology", "database": "AGR" }, { "id": "FB:FBgn0029950", "url": "https://alliancegenome.org/gene/FB:FBgn0029950#orthology", "database": "AGR" }, { "id": "HGNC:19119", "url": "https://alliancegenome.org/gene/HGNC:19119#orthology", "database": "AGR" }, { "id": "MGI:2384916", "url": "https://alliancegenome.org/gene/MGI:2384916#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q91ZP4-1", "protein_name": "Solute carrier family 5 member 4B", "gene_name": "Slc5a4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASTLSPSITPQTEEPPVVPVRIQNAADISVIVIYFIVVLAVGLWSMVRSNRGTVGGFFLAGHDMAWWPMGASLFASNIGSNHFVGLAGTGAASGIAIAAVEWNALLMVLVLGWVFLPIYIKAGVLTMPEYLRKRFGGKRLQIYLSVLSLFIMVALQTSSIIFSGAIFIQLALGLNLYLAVFILLAITAFYTVAGGLASVIYTDSVQTFIMLLGSLILMGFAFAEVGGYESFTEKYMNAIPSVVEGDNLTISPKCYTPQPDSFHVFRDPVTGDIPWPGLIFGMTILAIWYWCADQVIVQRCLCGKNMSHVKAACILCGYLKLLPMFLMVMPGMISRILYTDKVACVVPSECEKQCGTAVGCTNYAYPTLVLELMPDGLRGLMLSVMLASLMSSLTSIFNSASTLFTIDLYTKIRKKASERELMIAGRIFGMVLIAVSILWVPLVQVSQNGQLFHYIGSVSSYLGPPLGAVFMLAIFFKRVNEQGAFWGLMVGLVVGLIRLIAEFVYGTGSCVAPSNCPKIICGVHYMYFAIILFFVSIIVILGVSFLTEPIPDVHLYRLCWSLWNNTEERIDLDAEELETQEEAGGALEEDSEQSRGCLKRACCLLCGLQNTGPKLTKEEEAALRQKFSDTSEKPLWRTVMNINAVLLLGVAVFVHAYFA", "length": 660 }, "evidence": [ { "id": "SGD:S000001008", "url": "https://alliancegenome.org/gene/SGD:S000001008#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q92911-1", "protein_name": "Sodium/iodide cotransporter", "gene_name": "SLC5A5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEAVETGERPTFGAWDYGVFALMLLVSTGIGLWVGLARGGQRSAEDFFTGGRRLAALPVGLSLSASFMSAVQVLGVPSEAYRYGLKFLWMCLGQLLNSVLTALLFMPVFYRLGLTSTYEYLEMRFSRAVRLCGTLQYIVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTFYTAVGGMKAVVWTDVFQVVVMLSGFWVVLARGVMLVGGPRQVLTLAQNHSRINLMDFNPDPRSRYTFWTFVVGGTLVWLSMYGVNQAQVQRYVACRTEKQAKLALLINQVGLFLIVSSAACCGIVMFVFYTDCDPLLLGRISAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSINAMAAVTVEDLIKPRLRSLAPRKLVIISKGLSLIYGSACLTVAALSSLLGGGVLQGSFTVMGVISGPLLGAFILGMFLPACNTPGVLAGLGAGLALSLWVALGATLYPPSEQTMRVLPSSAARCVALSVNASGLLDPALLPANDSSRAPSSGMDASRPALADSFYAISYLYYGALGTLTTVLCGALISCLTGPTKRSTLAPGLLWWDLARQTASVAPKEEVAILDDNLVKGPEELPTGNKKPPGFLPTNEDRLFFLGQKELEGAGSWTPCVGHDGGRDQQETNL", "length": 643 }, "evidence": [ { "id": "HGNC:11040", "url": "https://alliancegenome.org/gene/HGNC:11040#orthology", "database": "AGR" }, { "id": "FB:FBgn0029950", "url": "https://alliancegenome.org/gene/FB:FBgn0029950#orthology", "database": "AGR" }, { "id": "RGD:69267", "url": "https://alliancegenome.org/gene/RGD:69267#orthology", "database": "AGR" }, { "id": "SGD:S000001008", "url": "https://alliancegenome.org/gene/SGD:S000001008#orthology", "database": "AGR" }, { "id": "MGI:2149330", "url": "https://alliancegenome.org/gene/MGI:2149330#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99PN0-1", "protein_name": "Sodium/iodide cotransporter", "gene_name": "Slc5a5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEGAEAGARATFGPWDYGVFATMLLVSTGIGLWVGLARGGQRSADDFFTGGRQLAAVPVGLSLAASFMSAVQVLGVPAEAARYGLKFLWMCVGQLLNSLLTALLFLPIFYRLGLTSTYQYLELRFSRAVRLCGTLQYLVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTLYTTVGGMKAVVWTDVFQVVVMLVGFWVILARGVMLMGGPWNVLSLAQNHSRINLMDFDPDPRSRYTFWTFVVGGSLVWLSMYGVNQAQVQRYVACHTERKAKLALLVNQLGLFLIVASAACCGIVMFVYYKDCDPLLTGRIAAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSINAMAAVTVEDLIKPRMPSLAPRKLVFISKGLSFIYGSTCLTVAALSSLLGGGVLQGSFTVMGVISGPLLGAFTLGMLLPACNTPGVLSGLTAGLAVSLWVAVGATLYPPGEQTMGVLPTSAAGCTNASVLPSPPGAANTSRGIPSSGMDSGRPAFADTFYAVSYLYYGALGTLTTMLCGALISYLTGPTKRSSLGPGLLWWDLARQTASVAPKEDTTTLEDSLVKGPEDIPAATKKPPGFRPEAETHPLYLGHDVETNL", "length": 618 }, "evidence": [ { "id": "HGNC:11040", "url": "https://alliancegenome.org/gene/HGNC:11040#orthology", "database": "AGR" }, { "id": "FB:FBgn0029950", "url": "https://alliancegenome.org/gene/FB:FBgn0029950#orthology", "database": "AGR" }, { "id": "RGD:69267", "url": "https://alliancegenome.org/gene/RGD:69267#orthology", "database": "AGR" }, { "id": "MGI:2149330", "url": "https://alliancegenome.org/gene/MGI:2149330#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9ET37-1", "protein_name": "Solute carrier family 5 member 4A", "gene_name": "Slc5a4a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASTASVSTSTASSELSSLSNNINNAADISVIVIYFVVVMAVGVWAMLKTNRSTVGGFFLAGRSMTWWPMGASLFASNIGSGHFVGLAGTGAASGIAVTAFESHSFALLLVLGWIFVPIYIKAGVMTMPEYLKKRFGGKRLQIYLSILFLFICVILTISADIFSGAIFIKLALGLNLYLAILILLAITAIFTITGGLASVIYTDTVQAVIMLVGSFILMVFAFVEVGGYESFTEKFMNAIPSVVEGDNLTINSRCYTPQPDSFHIFRDPVTGDIPWPGTAFGMPITALWYWCINQVIVQRCLCGKNLSHVKAACILCGYLKLLPLFFMVMPGMISRILYTDMVACVVPSECVKHCGVDVGCTNYAYPMLVLKLMPMGLRGLMLSVMLASLMSSLTSVFNSASTLFTIDLYTKIRKKASERELLIAGRLFVSVLIVTSILWVPIVEVSQGGQLVHYTEAISSYLGPPIAAVFLVAVFCKRANEQGAFWGLMVGLVMGLIRMIAEFSYGTGSCLAPSSCPKIICGVHYLYFAIILFFVCILVILGVSYLTKPIPDVHLHRLCWALRNSKEERIDLDAEDKEENGADDRTEEDQTEKPRGCLKKTCDLFCGLQRAEFKLTKVEEEALTDTTEKPFWRTVMNVNVILLLAVAAFFYGYFA", "length": 656 }, "evidence": [ { "id": "SGD:S000001008", "url": "https://alliancegenome.org/gene/SGD:S000001008#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9V9U1-1", "protein_name": "Sodium-dependent multivitamin transporter", "gene_name": "Smvt", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSSLLNATVLATAATVVPDSQFVFNATDYGVFALVLSISAAIGVYFGFFAKGEDTTEEYLMGGKRMKTIPIAISLVASQLSAISIMTIPAEMYAYGINWVFNVVCMVLVVPLLNYLVIPVFYNNNITNCYEYLEMRFCRKVRVLQTFIFILTMFFMLPIFIFLPSLAFAQVTGFNVHLINTVVCSICVFYTMFGGIKAVVWTDVIQAAIMVASVVLVGVLGAHRVGGFFEVLRIAGEGGRLDINYNFDLTTRSTIWNIFTSATMMWTGYVGLNQSCVQRIVSLPSLGHARRSLVLFGFGFILIMFFNCFTGIVIYSRFHDCDPIQSGHVSKVDKMVPYFVQDTVGNLWGMPGVFISCVFSAALSTLSASINSLGGVVYFDYIKPHIRHTEHRANVIMKLFVFFTGIYCILGGMVIENFNSILQVIYSIGGMSFGSTCGVFMLGMLVPKSHGRAALVGVLASIACMATIVILSWGRNHYDTLPTSTSACPASLNGTIKDISTASPLFLGSTTEAPVGEKEFSILDLSFNWYTVTGFVITWLIGIPLSYILKSGPDYKPNPKLLSPVVQPFVHYKLTPSDEPHQLNLEKPEKV", "length": 591 }, "evidence": [ { "id": "RGD:1564146", "url": "https://alliancegenome.org/gene/RGD:1564146#orthology", "database": "AGR" }, { "id": "MGI:2138890", "url": "https://alliancegenome.org/gene/MGI:2138890#orthology", "database": "AGR" }, { "id": "HGNC:11040", "url": "https://alliancegenome.org/gene/HGNC:11040#orthology", "database": "AGR" }, { "id": "RGD:69267", "url": "https://alliancegenome.org/gene/RGD:69267#orthology", "database": "AGR" }, { "id": "RGD:1311652", "url": "https://alliancegenome.org/gene/RGD:1311652#orthology", "database": "AGR" }, { "id": "HGNC:19119", "url": "https://alliancegenome.org/gene/HGNC:19119#orthology", "database": "AGR" }, { "id": "HGNC:28750", "url": "https://alliancegenome.org/gene/HGNC:28750#orthology", "database": "AGR" }, { "id": "SGD:S000001008", "url": "https://alliancegenome.org/gene/SGD:S000001008#orthology", "database": "AGR" }, { "id": "MGI:2149330", "url": "https://alliancegenome.org/gene/MGI:2149330#orthology", "database": "AGR" }, { "id": "MGI:2384916", "url": "https://alliancegenome.org/gene/MGI:2384916#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9V9U2-1", "protein_name": "Salty dog, isoform B", "gene_name": "salt", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MASSVSNLASTVATATTATLEDLHFSLTDYIVFSLMLSASAGIGVYFGFFSKAKNTTEEYLQGGKRMPTLPVAISLVSSQLSGVAMMSVPAETYSFGFNMIFVVWAMVLSVPVLIYIIVPVFYDNNVSNCYEYLELRFSKRTRQLVTITFILNQFLMLPVYMFVPSLAFSQVTGYNIHLINTVVSSICVFYTMLGGIKAVVWTDVVQGSVMLISVVLVAILGTSNTGGITNVLENAAEGGRFDFSFGIDPRLRLTFISGMASGLLMWTGKLGLDQSCVQRIVSLPSYGHAKRCLLMAGVGFLLIMSFTCFTGIIMFAYYYGCDPIQAGLVSKPDKLMPFFIQDIMGHMMGMPGVFISCVFSASLSSLSASLNSFAGVVYFDYIKPRINHSEAKANATMKLVIVVMGAYCIVGGFIVQNFNSIIQTMWTITGINMGAVVGVFCLGMFVPRCNAKVAVSGIAFSCLVMLWIIINGQMNFKAGLIKYDPLPNGLDQCEAKGFEVILNAIRNKNVTNVGTTAIPSLEAPKELTTAFDSNRDFSIYDTSFYWYKVLGALLVFAWAIPMSYVWPLDKEEKQNPKLYSPFVRSMLNKPSPVLELEELPLKTPLSEEQIKEKENGSATEA", "length": 622 }, "evidence": [ { "id": "RGD:1564146", "url": "https://alliancegenome.org/gene/RGD:1564146#orthology", "database": "AGR" }, { "id": "MGI:2138890", "url": "https://alliancegenome.org/gene/MGI:2138890#orthology", "database": "AGR" }, { "id": "HGNC:11040", "url": "https://alliancegenome.org/gene/HGNC:11040#orthology", "database": "AGR" }, { "id": "RGD:69267", "url": "https://alliancegenome.org/gene/RGD:69267#orthology", "database": "AGR" }, { "id": "RGD:1311652", "url": "https://alliancegenome.org/gene/RGD:1311652#orthology", "database": "AGR" }, { "id": "SGD:S000001008", "url": "https://alliancegenome.org/gene/SGD:S000001008#orthology", "database": "AGR" }, { "id": "MGI:2149330", "url": "https://alliancegenome.org/gene/MGI:2149330#orthology", "database": "AGR" }, { "id": "MGI:2384916", "url": "https://alliancegenome.org/gene/MGI:2384916#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VBK1-1", "protein_name": "Kin of rumpel, isoform D", "gene_name": "kumpel", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSTTADPVALGVNSPVEDVVAKTTTTVANAIAKTVAVISSTVSTSSTTGATSTISTSSSTPTTSTTFAYTPTPTPTQSASPSLEDGEEKLSVKDLSQALQHFGIVDYLVFIAMLAVCAVIGFYFGFIEKKQKKQKLAGKDGGGAAGVEERRGSEALDYLVGGRQMKVFPVALSLVASFVSGISLLGTSTEIYVYGTQYAFILVTLAISGAISWYIFLPVFCNLQLTSTYEYFERRFDRRVRIFGSCLFVVMNILWQPICIYVPALTLNQVSGISVSKIVPVTSFICILYTSVGGIKGVVWTDVIQGTVMIGSMLIVIIKGTLDLGGLSVVLDHNRQYDRLVGPDMTFDPTARMGVFALFVGGALFKLQANGINQAIVQRYLTLPNNKDVKKALVLSLIGFMFVMLMCVYIGLLAFAEFYHCDPITTGLARAKDQVIPLYVVKNVGHIPGLVGLFVAGVFSAALSSLSTALNSLSGVILTDFVEPFRKKPLTERQTAYLLRGVVISFGLISMASVPIVQRLGLVMQLSSTVAAITCGPLLGAFSVGMLLPFVKTESLLTGISCASSFTAYIVVRAQIAIFTGSLTFPAKPVSIQDCDYTFDLPANWNATTTATPTESTSHGIHEISFLWYTAVGSVGTVLGSLLATLYFGRQDPRVVDKELISPVLRKFWYGKYESVASEEKNNFNLHESETQLKLEQP", "length": 698 }, "evidence": [ { "id": "RGD:1564146", "url": "https://alliancegenome.org/gene/RGD:1564146#orthology", "database": "AGR" }, { "id": "MGI:2138890", "url": "https://alliancegenome.org/gene/MGI:2138890#orthology", "database": "AGR" }, { "id": "HGNC:11040", "url": "https://alliancegenome.org/gene/HGNC:11040#orthology", "database": "AGR" }, { "id": "RGD:69267", "url": "https://alliancegenome.org/gene/RGD:69267#orthology", "database": "AGR" }, { "id": "RGD:1311652", "url": "https://alliancegenome.org/gene/RGD:1311652#orthology", "database": "AGR" }, { "id": "HGNC:19119", "url": "https://alliancegenome.org/gene/HGNC:19119#orthology", "database": "AGR" }, { "id": "HGNC:28750", "url": "https://alliancegenome.org/gene/HGNC:28750#orthology", "database": "AGR" }, { "id": "SGD:S000001008", "url": "https://alliancegenome.org/gene/SGD:S000001008#orthology", "database": "AGR" }, { "id": "MGI:2149330", "url": "https://alliancegenome.org/gene/MGI:2149330#orthology", "database": "AGR" }, { "id": "MGI:2384916", "url": "https://alliancegenome.org/gene/MGI:2384916#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VGP3-1", "protein_name": "Brother of rumpel", "gene_name": "bumpel", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSNIEEVLGELQRFAWPDYVAFVSMFLLCIGIGIYFGFMNKSVSEDDYMLGGRKMLVIPIAFSLVASFVSGITLLGLPTEVYSYGIQYLYVSCGVIGMGVVMGVFYLPVFHDLNITSTYEYLEVRFDRRLRLYGSVMFAIMNVAYLPIVIYVPALAFNQVTGIGVHTITPIVCIICVFYTSLGGLKAVVWTDVVQAISMLGALCLVAIKGTRDIGGAGVVLERAWSSDRLEAPDLSIDPTVRHTFWCLFFGGIVYWTQTNAVSQNMIQRYLSLPSLGDARKALCIFCVGVLILMALCGYNGLLIYATYQNCDPLTTKLAKARDQLLPLFVMKTLGELPGMTGLFIAGVFSAALSSLSTCLNSMSAVVLEDFVKPYVKKPLSSSAINWIMRLVVVGVGVLCVCLVYVVEHMGTVLQLTMSLEAITNGPLFGIFTIGLFLPWINGNSALVGGVMGVIAMSWVSLNAQWAIASGAITYKTKPLNVEQCDYSFNVTTSLANTTHLGASAEDIFPLYRISYMWYTTFGASITIFVALLGTFVFGKNNPNKVDPVLLTPCIRKFFAFGSEKHMDAFRPDIPLQHKLRNDEVAL", "length": 587 }, "evidence": [ { "id": "RGD:1564146", "url": "https://alliancegenome.org/gene/RGD:1564146#orthology", "database": "AGR" }, { "id": "MGI:2138890", "url": "https://alliancegenome.org/gene/MGI:2138890#orthology", "database": "AGR" }, { "id": "HGNC:11040", "url": "https://alliancegenome.org/gene/HGNC:11040#orthology", "database": "AGR" }, { "id": "RGD:69267", "url": "https://alliancegenome.org/gene/RGD:69267#orthology", "database": "AGR" }, { "id": "RGD:1311652", "url": "https://alliancegenome.org/gene/RGD:1311652#orthology", "database": "AGR" }, { "id": "HGNC:19119", "url": "https://alliancegenome.org/gene/HGNC:19119#orthology", "database": "AGR" }, { "id": "HGNC:28750", "url": "https://alliancegenome.org/gene/HGNC:28750#orthology", "database": "AGR" }, { "id": "SGD:S000001008", "url": "https://alliancegenome.org/gene/SGD:S000001008#orthology", "database": "AGR" }, { "id": "MGI:2149330", "url": "https://alliancegenome.org/gene/MGI:2149330#orthology", "database": "AGR" }, { "id": "MGI:2384916", "url": "https://alliancegenome.org/gene/MGI:2384916#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VLR8-1", "protein_name": "Sodium/solute co-transporter-like 5A11", "gene_name": "SLC5A11", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEAVAKKGMENYRFGSVDYAVFLGMIVLSTSTGIYFGCIKKSKVKLEEAEPTLPTTTPKRRKHDFGSEKMSEYLLGSRNLKVFPVAMSLIASYISGVTILGTTSEIYNYGTQYWFIAIAIMLQGIAVSYVYIPVFSALQVGSSYEYLEMRFHSVVRSIASFMFILDEILFLPFIVYVPAIALNQVSGINLHVIAVVIVVVCVFYTFVGGIKAVVHTDAWQVLVMFLSVLAVAILATVYANGLNVLFDDAAKGGRLIFNNTNPSPYVRHTVWSVLIGGFSYWTSFNAVNQTMVQRYMSLPSLKKARASMAIFTIGVAAFVSVCCYVGLLIYEMYKDCDPLSAGLITHDDQLLPLFVVQSVGHIYGMSGLFIAGIFGAALSSLSVVLNSTSLVILEDIVRGCFKMQPSERASTILVKSTVIVLGFVALSLVFVLEQLSGILSICTSMTAIAAGTTFGLFTLGMLVPWANTVGTAVGGIASALLAGWISFGTQFTIAAGELNSQKLPVSVEGCVGNVTLRENIWVDEEQVFPLYRLSYHWINPIGVATVIVVGALVSLVTKPTNMKTLDPDLISPVIHRFLPKECFSGRNLHAQAHKNLLNVS", "length": 600 }, "evidence": [ { "id": "RGD:1564146", "url": "https://alliancegenome.org/gene/RGD:1564146#orthology", "database": "AGR" }, { "id": "MGI:2138890", "url": "https://alliancegenome.org/gene/MGI:2138890#orthology", "database": "AGR" }, { "id": "HGNC:11040", "url": "https://alliancegenome.org/gene/HGNC:11040#orthology", "database": "AGR" }, { "id": "RGD:69267", "url": "https://alliancegenome.org/gene/RGD:69267#orthology", "database": "AGR" }, { "id": "RGD:1311652", "url": "https://alliancegenome.org/gene/RGD:1311652#orthology", "database": "AGR" }, { "id": "HGNC:19119", "url": "https://alliancegenome.org/gene/HGNC:19119#orthology", "database": "AGR" }, { "id": "HGNC:28750", "url": "https://alliancegenome.org/gene/HGNC:28750#orthology", "database": "AGR" }, { "id": "SGD:S000001008", "url": "https://alliancegenome.org/gene/SGD:S000001008#orthology", "database": "AGR" }, { "id": "MGI:2149330", "url": "https://alliancegenome.org/gene/MGI:2149330#orthology", "database": "AGR" }, { "id": "MGI:2384916", "url": "https://alliancegenome.org/gene/MGI:2384916#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VQ85-1", "protein_name": "Sodium-coupled monocarboxylate transporter 1", "gene_name": "CG33124-PB", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDTYRFGTVDYTVFLGVTILSIAIGLYFGWIKKTKKEMESSPADTPEISIPNFGSKKMNEYLMGSGHLKVFPVAMSLIASFISGVAILGNPSEIYYYGTQYSLIVLAIVIQGLAVSYIYLPVFSALQVRSSYEYLGMRFHPLIRNIVSIMFVIEVLLYTPFVVFVPALALNQASGLNIHMIEVLIIVVCVIYTLLGGLKAVVHTDIWQVVIMFASVVVVAILATCYITDLDDFFESLVDGGRLIFGNINPSPYVRNTVWSVVIGGAFYWTSITAVHQTMVHRYMSLPNLKMARTSIAFFVLGSIIFYSVLSFLGLLIFNMYKDCDPLSAGQIMNNDQLVPLFVVQSVGHIYGIPGLFIAGIFGAGLSSLSVFLNSTSLVILQDIVRGCFKMQPGETASAIIVKATIVIMGALVFGEVLLLEKVSGILSICMSLVAIATSSTFGIFTLAVLVPWANTVGTAVGGIAGFLLTGWITFGSQIAAASGQLHHHRLPVSVASCPGNVTARENVWVDEEQVFPLFRLSFHWINPIGALTVVVVGSLVSLVTKPTDIKSLDSDLISPVIHRFLPKECFKQRNLDKSEATDIYTIT", "length": 588 }, "evidence": [ { "id": "RGD:1564146", "url": "https://alliancegenome.org/gene/RGD:1564146#orthology", "database": "AGR" }, { "id": "MGI:2138890", "url": "https://alliancegenome.org/gene/MGI:2138890#orthology", "database": "AGR" }, { "id": "HGNC:11040", "url": "https://alliancegenome.org/gene/HGNC:11040#orthology", "database": "AGR" }, { "id": "RGD:69267", "url": "https://alliancegenome.org/gene/RGD:69267#orthology", "database": "AGR" }, { "id": "RGD:1311652", "url": "https://alliancegenome.org/gene/RGD:1311652#orthology", "database": "AGR" }, { "id": "HGNC:19119", "url": "https://alliancegenome.org/gene/HGNC:19119#orthology", "database": "AGR" }, { "id": "HGNC:28750", "url": "https://alliancegenome.org/gene/HGNC:28750#orthology", "database": "AGR" }, { "id": "SGD:S000001008", "url": "https://alliancegenome.org/gene/SGD:S000001008#orthology", "database": "AGR" }, { "id": "MGI:2149330", "url": "https://alliancegenome.org/gene/MGI:2149330#orthology", "database": "AGR" }, { "id": "MGI:2384916", "url": "https://alliancegenome.org/gene/MGI:2384916#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "solute:sodium symporter activity", "id": "GO:0015370", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015370", "evidence": [ { "database": "UniProtKB", "id": "Q9W3R0", "url": "https://www.uniprot.org/uniprotkb/Q9W3R0" } ], "pmid": "" }, { "name": "symporter activity", "id": "GO:0015293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015293", "evidence": [ { "database": "UniProtKB", "id": "Q9W3R0", "url": "https://www.uniprot.org/uniprotkb/Q9W3R0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9W3R0", "url": "https://www.uniprot.org/uniprotkb/Q9W3R0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "Q9W3R0", "url": "https://www.uniprot.org/uniprotkb/Q9W3R0" } ], "pmid": "" }, { "name": "sodium ion transport", "id": "GO:0006814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006814", "evidence": [ { "database": "UniProtKB", "id": "Q9W3R0", "url": "https://www.uniprot.org/uniprotkb/Q9W3R0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 247, "end_pos": 249, "annotation": "n_glycosylation_sequon" }, { "start_pos": 499, "end_pos": 501, "annotation": "n_glycosylation_sequon" }, { "start_pos": 49, "end_pos": 51, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 140, "end_pos": 142 }, { "start_pos": 247, "end_pos": 249 }, { "start_pos": 499, "end_pos": 501 }, { "start_pos": 49, "end_pos": 51 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9W3R1-1", "uniprot_ac": "Q9W3R1", "uniprot_id": "Q9W3R1_DROME", "mass": { "chemical_mass": 41367.0, "monoisotopic_mass": 41367.0 }, "refseq": { "ac": "NP_572396", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572396" }, "gene_names": [ { "name": "Dmel\\CG15035", "type": "recommended", "evidence": [ { "id": "Q9W3R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3R1" } ] }, { "name": "CG15035", "type": "synonym", 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"https://www.uniprot.org/uniprotkb/Q9W3R1" } ] } ], "protein_names": [ { "name": "Protein phosphatase", "type": "recommended", "evidence": [ { "id": "Q9W3R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3R1/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.16", "type": "synonym", "evidence": [ { "id": "Q9W3R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3R1/entry#names_and_taxonomy" } ] }, { "name": "CG15035-PA", "type": "synonym", "evidence": [ { "id": "NP_572396", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572396" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_572396", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572396" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W3R1", "url": "https://www.uniprot.org/uniprotkb/Q9W3R1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG15035", "url": "https://www.uniprot.org/uniprotkb/Q9W3R1", "locus": { "chromosome": "X", "start_pos": 7401698, "end_pos": 7403174, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0029949", "url": "https://www.ensemblgenomes.org/id/FBgn0029949" } ] } } ], "crossref": [ { "id": "FB:FBgn0029949", "url": "https://alliancegenome.org/gene/FB:FBgn0029949", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0029949", "url": "https://bgee.org/?page=gene&gene_id=FBgn0029949", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0029949", "url": "https://flybase.org/reports/FBgn0029949", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "31673", "url": "https://www.ncbi.nlm.nih.gov/gene/31673", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001932", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001932", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039123", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039123", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG15035", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG15035", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QKACNSL", "url": "https://omabrowser.org/oma/group/QKACNSL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W3R1", "url": "https://www.orthodb.org/?gene=Q9W3R1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12320", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12320", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12320:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12320:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13672", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13672", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_572396", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572396", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "20629", "url": "https://www.rhea-db.org/rhea/20629", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "47004", "url": "https://www.rhea-db.org/rhea/47004", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q9W3R1", "url": "https://www.uniprot.org/uniprotkb/Q9W3R1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W3R1-1", "url": "https://www.uniprot.org/uniprotkb/Q9W3R1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDVETSLDIEEMRRRIQQGINRCCEQLLEIAMILTHKGGQVLNRLKGASFPELAQNSENIGNGSMSENQNQRLDPMTSAQYTTLGFGNFDGEGDYLRQKNKINIQLPRLVSVTCGFAKDHIRYPEYNRGKFGEDAWFMSSSPQACIMGVADGVGGWRNYGVDPGKFSMTLMRSCERMSHAPDFKPNRPEILLERAYFDLLDQKCPIVGSCTACILALKRDDSTLYAANIGDSGFLVVRSGKVVCRSQEQQHQFNTPYQLASPPPGYDFDAVSDGPESADTIQFPMQLGDVILLATDGVYDNVPESFLVEVLTEMSGISNPVRLQMAANTVALMARTLSFSPKHDSPFSQNARKHDIDAWGGKPDDITVLLASVV", "length": 374, "header": "tr|Q9W3R1-1|Q9W3R1_DROME Isoform 1 of Protein phosphatase OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG15035 PE=3 SV=1 CANONICAL=Q9W3R1-1" }, "isoforms": [ { "isoform_ac": "Q9W3R1-1", "url": "https://www.uniprot.org/uniprotkb/Q9W3R1/entry#Q9W3R1-1", "sequence": { "sequence": "MDVETSLDIEEMRRRIQQGINRCCEQLLEIAMILTHKGGQVLNRLKGASFPELAQNSENIGNGSMSENQNQRLDPMTSAQYTTLGFGNFDGEGDYLRQKNKINIQLPRLVSVTCGFAKDHIRYPEYNRGKFGEDAWFMSSSPQACIMGVADGVGGWRNYGVDPGKFSMTLMRSCERMSHAPDFKPNRPEILLERAYFDLLDQKCPIVGSCTACILALKRDDSTLYAANIGDSGFLVVRSGKVVCRSQEQQHQFNTPYQLASPPPGYDFDAVSDGPESADTIQFPMQLGDVILLATDGVYDNVPESFLVEVLTEMSGISNPVRLQMAANTVALMARTLSFSPKHDSPFSQNARKHDIDAWGGKPDDITVLLASVV", "length": 374, "header": "tr|Q9W3R1-1|Q9W3R1_DROME Isoform 1 of Protein phosphatase OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG15035 PE=3 SV=1 CANONICAL=Q9W3R1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W3R1", "url": "https://www.uniprot.org/uniprotkb/Q9W3R1" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W3R1", "url": "https://www.uniprot.org/uniprotkb/Q9W3R1" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3R1", "url": "https://www.uniprot.org/uniprotkb/Q9W3R1" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3R1", "url": "https://www.uniprot.org/uniprotkb/Q9W3R1" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W3R1", "url": "https://www.uniprot.org/uniprotkb/Q9W3R1" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W3R1", "url": "https://www.uniprot.org/uniprotkb/Q9W3R1" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W3R1", "url": "https://www.uniprot.org/uniprotkb/Q9W3R1" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3R1", "url": "https://www.uniprot.org/uniprotkb/Q9W3R1" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3R1", "url": "https://www.uniprot.org/uniprotkb/Q9W3R1" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W3R1", "url": "https://www.uniprot.org/uniprotkb/Q9W3R1" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W3R1", "url": "https://www.uniprot.org/uniprotkb/Q9W3R1" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG15035", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG15035", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ACD6B694-1", "protein_name": "Protein phosphatase", "gene_name": "pptc7b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLSVLSYGRIVARAVLGGLSQTDGRDYSLITASCGFGKDFRKGILKKGMCYGDDACFIARHKSADVLGVADGVGGWRDYGVDPSQFSATLMKTCERLVKEGRFTPSSPVGILTSGYYELLQNKVPLLGSSTACIVVLDRRSHRIHTCNLGDSGFLVVRGGEVVHRSDEQQHYFNTPFQLSIAPPGAEGVVLSDSPEAADSSSFDVQLGDIILTATDGLFDNMPDYMILQELKKLKNTNYDSIQQTARSIAEQAHELAYDPNYMSPFAQFACDNGLNVRGGKPDDITVLLSIVAEYTD", "length": 297 }, "evidence": [ { "id": "MGI:2444593", "url": "https://alliancegenome.org/gene/MGI:2444593#orthology", "database": "AGR" }, { "id": "HGNC:30695", "url": "https://alliancegenome.org/gene/HGNC:30695#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D4A520-1", "protein_name": "Protein phosphatase", "gene_name": "Pptc7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSVLSYGRLVARAVLGGLSQTDPRAGGGGGGGSGDYGLVTAGCGFGKDFRKGLLKKGACYGDDACFVARHRSADVLGVADGVGGWRDYGVDPSQFSGTLMRTCERLVKEGRFVPSNPVGILTTSYCELLQNKVPLLGSSTACIVVLDRSSHRLHTANLGDSGFLVVRGGEVVHRSDEQQHYFNTPFQLSIAPPEAEGVVLSDSPDAADSTSFDVQLGDIILTATDGLFDNMPDYMILQELKKLKNSNYESIQRTARSIAEQAHELAYDPNYMSPFAQFACDNGLNVRGGKPDDITVLLSIVAEYTD", "length": 307 }, "evidence": [ { "id": "RGD:1310383", "url": "https://alliancegenome.org/gene/RGD:1310383#orthology", "database": "AGR" }, { "id": "MGI:2444593", "url": "https://alliancegenome.org/gene/MGI:2444593#orthology", "database": "AGR" }, { "id": "HGNC:30695", "url": "https://alliancegenome.org/gene/HGNC:30695#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-74", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-74#orthology", "database": "AGR" }, { "id": "FB:FBgn0029949", "url": "https://alliancegenome.org/gene/FB:FBgn0029949#orthology", "database": "AGR" }, { "id": "SGD:S000001118", "url": "https://alliancegenome.org/gene/SGD:S000001118#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P38797-1", "protein_name": "Protein phosphatase 2C homolog 7, mitochondrial", "gene_name": "PTC7", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MFANVGFRTLRVSRGPLYGSCSQIISFSKRTFYSSAKSGYQSNNSHGDAYSSGSQSGPFTYKTAVAFQPKDRDDLIYQKLKDSIRSPTGEDNYFVTSNNVHDIFAGVADGVGGWAEHGYDSSAISRELCKKMDEISTALAENSSKETLLTPKKIIGAAYAKIRDEKVVKVGGTTAIVAHFPSNGKLEVANLGDSWCGVFRDSKLVFQTKFQTVGFNAPYQLSIIPEEMLKEAERRGSKYILNTPRDADEYSFQLKKKDIIILATDGVTDNIATDDIELFLKDNAARTNDELQLLSQKFVDNVVSLSKDPNYPSVFAQEISKLTGKNYSGGKEDDITVVVVRVD", "length": 343 }, "evidence": [ { "id": "RGD:1310383", "url": "https://alliancegenome.org/gene/RGD:1310383#orthology", "database": "AGR" }, { "id": "MGI:2444593", "url": "https://alliancegenome.org/gene/MGI:2444593#orthology", "database": "AGR" }, { "id": "HGNC:30695", "url": "https://alliancegenome.org/gene/HGNC:30695#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-74", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-74#orthology", "database": "AGR" }, { "id": "FB:FBgn0029949", "url": "https://alliancegenome.org/gene/FB:FBgn0029949#orthology", "database": "AGR" }, { "id": "SGD:S000001118", "url": "https://alliancegenome.org/gene/SGD:S000001118#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q5U3N5-1", "protein_name": "Protein phosphatase PTC7 homolog", "gene_name": "pptc7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLSVLSYGRLVARAVIGGLSQTDSRDYSLVSASFGFGKDFRKGILKKGMCYGDDACFIARHRSADVLGVADGVGGWRDYGVDPSQFSGTLMRTCERLVKEGRFVPSNPVGILTTSYYELLQNKVPLLGSSTACIVVLDRQSHRLHTANLGDSGFLVVRGGEVVHRSDEQQHYFNTPFQLSIAPPEAEGSVLSDSPDAADSSSFDVQLGDIILTATDGLFDNMPDYMILQELKKLKNTNYESTQQTAKSIAEQAHVLAYDPNYMSPFAQFACDNGLNVRGGKPDDITVLLSIVAEYTD", "length": 297 }, "evidence": [ { "id": "RGD:1310383", "url": "https://alliancegenome.org/gene/RGD:1310383#orthology", "database": "AGR" }, { "id": "MGI:2444593", "url": "https://alliancegenome.org/gene/MGI:2444593#orthology", "database": "AGR" }, { "id": "HGNC:30695", "url": "https://alliancegenome.org/gene/HGNC:30695#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-74", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-74#orthology", "database": "AGR" }, { "id": "FB:FBgn0029949", "url": "https://alliancegenome.org/gene/FB:FBgn0029949#orthology", "database": "AGR" }, { "id": "SGD:S000001118", "url": "https://alliancegenome.org/gene/SGD:S000001118#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6NVE9-1", "protein_name": "Protein phosphatase PTC7 homolog", "gene_name": "Pptc7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSVLSYGRLVARAVLGGLSQTDPRAGGGGGGGGGSSGDYGLVTAGCGFGKDFRKGLLKKGACYGDDACFVARHRSADVLGVADGVGGWRDYGVDPSQFSGTLMRTCERLVKEGRFVPSNPVGILTTSYCELLQNKVPLLGSSTACIVVLDRSSHRLHTANLGDSGFLVVRGGEVVHRSDEQQHYFNTPFQLSIAPPEAEGVVLSDSPDAADSTSFDVQLGDIILTATDGLFDNMPDYMILQELKKLKNSNYESIQRTARSIAEQAHELAYDPNYMSPFAQFACDNGLNVRGGKPDDITVLLSIVAEYTD", "length": 310 }, "evidence": [ { "id": "RGD:1310383", "url": "https://alliancegenome.org/gene/RGD:1310383#orthology", "database": "AGR" }, { "id": "MGI:2444593", "url": "https://alliancegenome.org/gene/MGI:2444593#orthology", "database": "AGR" }, { "id": "HGNC:30695", "url": "https://alliancegenome.org/gene/HGNC:30695#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-74", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-74#orthology", "database": "AGR" }, { "id": "FB:FBgn0029949", "url": "https://alliancegenome.org/gene/FB:FBgn0029949#orthology", "database": "AGR" }, { "id": "SGD:S000001118", "url": "https://alliancegenome.org/gene/SGD:S000001118#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NI37-1", "protein_name": "Protein phosphatase PTC7 homolog", "gene_name": "PPTC7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFSVLSYGRLVARAVLGGLSQTDPRAGGGGGGDYGLVTAGCGFGKDFRKGLLKKGACYGDDACFVARHRSADVLGVADGVGGWRDYGVDPSQFSGTLMRTCERLVKEGRFVPSNPIGILTTSYCELLQNKVPLLGSSTACIVVLDRTSHRLHTANLGDSGFLVVRGGEVVHRSDEQQHYFNTPFQLSIAPPEAEGVVLSDSPDAADSTSFDVQLGDIILTATDGLFDNMPDYMILQELKKLKNSNYESIQQTARSIAEQAHELAYDPNYMSPFAQFACDNGLNVRGGKPDDITVLLSIVAEYTD", "length": 304 }, "evidence": [ { "id": "RGD:1310383", "url": "https://alliancegenome.org/gene/RGD:1310383#orthology", "database": "AGR" }, { "id": "MGI:2444593", "url": "https://alliancegenome.org/gene/MGI:2444593#orthology", "database": "AGR" }, { "id": "HGNC:30695", "url": "https://alliancegenome.org/gene/HGNC:30695#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-74", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-74#orthology", "database": "AGR" }, { "id": "FB:FBgn0029949", "url": "https://alliancegenome.org/gene/FB:FBgn0029949#orthology", "database": "AGR" }, { "id": "SGD:S000001118", "url": "https://alliancegenome.org/gene/SGD:S000001118#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VAH4-1", "protein_name": "Protein phosphatase PTC7 homolog fig", "gene_name": "fig", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MITCLRNWPLLLKRFSVHQIHQFTQLSGRFERPPQSGKSSRDPYLVTVVQGRSKKPRFPGERSNQRFGEDSWFVSSTPLAEVMGVADGVGGWRDLGVDAGRFAKELMSCCSGQTQLSDFDGRSPRNMLIAGFQELSHREHPVVGSSTACLATMHRKDCTLYTANLGDSGFLVVRNGRVLHRSVEQTHDFNTPYQLTVPPEDRKESYYCDKPEMAVSTRHSLLPGDLVLLATDGLFDNMPESMLLSILNGLKERGEHDLLVGASRVVEKARELSMNASFQSPFAIKARQHNVSYSGGGKPDDITLILSSVEVPNA", "length": 314 }, "evidence": [ { "id": "RGD:1310383", "url": "https://alliancegenome.org/gene/RGD:1310383#orthology", "database": "AGR" }, { "id": "MGI:2444593", "url": "https://alliancegenome.org/gene/MGI:2444593#orthology", "database": "AGR" }, { "id": "HGNC:30695", "url": "https://alliancegenome.org/gene/HGNC:30695#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-74", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-74#orthology", "database": "AGR" }, { "id": "SGD:S000001118", "url": "https://alliancegenome.org/gene/SGD:S000001118#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W0E2-1", "protein_name": "Protein phosphatase", "gene_name": "Dmel\\CG12091", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MHSSLSWTSRAISRALRSSFSTLLETATGGGSGAAAKGATKSGATPGSSGAPRPRFVSVVCGFAKDNLRHKYKPGKYGEDSWFKASTASADVMGVADGVGGWRSYGIDPGEFSSFLMRTCERLVQCSHFNPQRPVNLLAYSYCELMEQKKPILGSSTACVLILNRETSTVHTANIGDSGFVVVREGQVVHKSEEQQHYFNTPFQLSLPPPGHGPNVLSDSPESADTMSFPVRDGDVILIATDGVFDNVPEDLMLQVLSEVEGERDPVKLQMTANSLALMARTLSLNSEFLSPFALSARRNNIQARGGKPDDITVVLATVAM", "length": 321 }, "evidence": [ { "id": "RGD:1310383", "url": "https://alliancegenome.org/gene/RGD:1310383#orthology", "database": "AGR" }, { "id": "MGI:2444593", "url": "https://alliancegenome.org/gene/MGI:2444593#orthology", "database": "AGR" }, { "id": "HGNC:30695", "url": "https://alliancegenome.org/gene/HGNC:30695#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-74", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-74#orthology", "database": "AGR" }, { "id": "SGD:S000001118", "url": "https://alliancegenome.org/gene/SGD:S000001118#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9W3R1", "url": "https://www.uniprot.org/uniprotkb/Q9W3R1" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "Q9W3R1", "url": "https://www.uniprot.org/uniprotkb/Q9W3R1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9W3R1", "url": "https://www.uniprot.org/uniprotkb/Q9W3R1" } ], "pmid": "" }, { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "Q9W3R1", "url": "https://www.uniprot.org/uniprotkb/Q9W3R1" } ], "pmid": "" }, { "name": "phosphoprotein phosphatase activity", "id": "GO:0004721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004721", "evidence": [ { "database": "UniProtKB", "id": "Q9W3R1", "url": "https://www.uniprot.org/uniprotkb/Q9W3R1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of ubiquinone biosynthetic process", "id": "GO:0010795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010795", "evidence": [ { "database": "UniProtKB", "id": "Q9W3R1", "url": "https://www.uniprot.org/uniprotkb/Q9W3R1" } ], "pmid": "" }, { "name": "positive regulation of ubiquinone biosynthetic process", "id": "GO:1904775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904775", "evidence": [ { "database": "UniProtKB", "id": "Q9W3R1", "url": "https://www.uniprot.org/uniprotkb/Q9W3R1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 62, "end_pos": 64, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20629", "name": "", "equation": "O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q05547-1", "Q27884-1", "Q7K4Q5-1", "Q9VAH4-1", "A8DYY5-1", "O76932-1", "P11612-1", "P40421-1", "P48461-1", "Q6NN85-1", "Q86BN8-1", "Q9VJ07-1", "P12982-1", "P48462-1", "M9PFN0-1", "O46084-1", "Q9VRG7-1", "Q27889-1", "Q9VXF1-1", "Q9VVW5-1", "Q9VWF4-1", "P48456-1", "X2JEB8-1", "Q9VWE4-1", "P23696-1", "Q9VQL9-1", "Q9XZ16-1", "M9PI51-1", "Q7KVM5-1", "Q9W3R1-1", "Q9W173-1", "Q9W0E2-1", "Q9W2A5-1", "Q9W147-1", "Q9VLW7-1" ], "evidence": [ { "id": "20629", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20629" } ] }, { "id": "47004", "name": "", "equation": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q05547-1", "Q27884-1", "Q7K4Q5-1", "Q9VAH4-1", "A8DYY5-1", "O76932-1", "P11612-1", "P40421-1", "P48461-1", "Q6NN85-1", "Q9VJ07-1", "P12982-1", "P48462-1", "Q86BN8-1", "O46084-1", "Q9VRG7-1", "Q27889-1", "Q9VXF1-1", "Q9VVW5-1", "Q9VWF4-1", "P48456-1", "X2JEB8-1", "Q9VWE4-1", "P23696-1", "Q9VQL9-1", "Q9XZ16-1", "M9PI51-1", "Q7KVM5-1", "Q9W3R1-1", "Q9W173-1", "Q9W0E2-1", "Q9W2A5-1", "Q9W147-1", "Q9VLW7-1" ], "evidence": [ { "id": "47004", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/47004" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A8DYY5", "gene_name": "", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A8DYY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8DYY5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A8DYY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8DYY5" } ] } ] }, { "uniprot_ac": "M9PFN0", "gene_name": "hzg", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "M9PFN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9PFN0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "M9PFN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9PFN0" } ] } ] }, { "uniprot_ac": "M9PI51", "gene_name": "Dmel\\CG10089", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "M9PI51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9PI51" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "M9PI51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9PI51" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "M9PI51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9PI51" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "M9PI51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/M9PI51" } ] } ] }, { "uniprot_ac": "O46084", "gene_name": "Pgam5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O46084", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O46084" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O46084", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O46084" } ] } ] }, { "uniprot_ac": "O76932", "gene_name": "Pp4-19C", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "O76932", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O76932" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "O76932", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O76932" } ] } ] }, { "uniprot_ac": "P11612", "gene_name": "PpY-55A", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P11612", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11612" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P11612", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P11612" } ] } ] }, { "uniprot_ac": "P12982", "gene_name": "Pp1-87B", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P12982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P12982" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P12982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P12982" } ] } ] }, { "uniprot_ac": "P23696", "gene_name": "mts", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P23696", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P23696" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P23696", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P23696" } ] } ] }, { "uniprot_ac": "P40421", "gene_name": "rdgC", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P40421", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P40421" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P40421", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P40421" } ] } ] }, { "uniprot_ac": "P48456", "gene_name": "CanA1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P48456", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48456" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P48456", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48456" } ] } ] }, { "uniprot_ac": "P48461", "gene_name": "Pp1alpha-96A", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P48461", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48461" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P48461", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48461" } ] } ] }, { "uniprot_ac": "P48462", "gene_name": "flw", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P48462", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48462" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P48462", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P48462" } ] } ] }, { "uniprot_ac": "Q05547", "gene_name": "Pp1-13C", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q05547", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05547" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q05547", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q05547" } ] } ] }, { "uniprot_ac": "Q27884", "gene_name": "PpV", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q27884", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q27884" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q27884", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q27884" } ] } ] }, { "uniprot_ac": "Q27889", "gene_name": "Pp2B-14D", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q27889", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q27889" } ] 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}, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9W3S3-1", "uniprot_ac": "Q9W3S3", "uniprot_id": "Q9W3S3_DROME", "mass": { "chemical_mass": 20038.0, "monoisotopic_mass": 20038.0 }, "refseq": { "ac": "NP_572384", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572384" }, "gene_names": [ { "name": "Dmel\\CG8300", "type": "recommended", "evidence": [ { "id": "Q9W3S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3S3" } ] }, { "name": "CG8300", "type": "synonym", "evidence": [ { "id": "NP_572384", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572384" }, { "id": "Q9W3S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3S3" } ] }, { "name": "Dmel\\CG8300", "type": "synonym", "evidence": [ { "id": "NP_572384", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572384" } ] }, { "name": "Dmel_CG8300", "type": "synonym", "evidence": [ { "id": "Q9W3S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3S3" } ] } ], "protein_names": [ { "name": "CG8300-PA", "type": "synonym", "evidence": [ { "id": "NP_572384", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572384" } ] }, { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "Q9W3S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3S3/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_572384", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572384" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W3S3", "url": "https://www.uniprot.org/uniprotkb/Q9W3S3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG8300", "url": "https://www.uniprot.org/uniprotkb/Q9W3S3", "locus": { "chromosome": "X", "start_pos": 7106345, "end_pos": 7104885, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0029937", "url": "https://www.ensemblgenomes.org/id/FBgn0029937" } ] } } ], "crossref": [ { "id": "FB:FBgn0029937", "url": "https://alliancegenome.org/gene/FB:FBgn0029937", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0029937", "url": "https://bgee.org/?page=gene&gene_id=FBgn0029937", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0029937", "url": "https://flybase.org/reports/FBgn0029937", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "31658", "url": "https://www.ncbi.nlm.nih.gov/gene/31658", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028260", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028260", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG8300", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG8300", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KCYDVHL", "url": "https://omabrowser.org/oma/group/KCYDVHL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W3S3", "url": "https://www.orthodb.org/?gene=Q9W3S3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31206", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31206", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31206:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31206:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14774", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14774", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_572384", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572384", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W3S3", "url": "https://www.uniprot.org/uniprotkb/Q9W3S3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W3S3-1", "url": "https://www.uniprot.org/uniprotkb/Q9W3S3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAERNKSGEVRSAAGGLELASASGASASETDNVSALELQSNKRMLYFSDGVMEELSSGSEDEADAEMGDKCYDVHLNESEMPLGPRLRYKASRMGNRFLAGIDYVGGGLAHLLGITSSKYASELENYHRAKEHGDEDLDNWHPRAMSTTTSSSNNNSSGNNNRNETIVLCEPTRSEATLPPTRQ", "length": 185, "header": "tr|Q9W3S3-1|Q9W3S3_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG8300 PE=1 SV=1 CANONICAL=Q9W3S3-1" }, "isoforms": [ { "isoform_ac": "Q9W3S3-1", "url": "https://www.uniprot.org/uniprotkb/Q9W3S3/entry#Q9W3S3-1", "sequence": { "sequence": "MSAERNKSGEVRSAAGGLELASASGASASETDNVSALELQSNKRMLYFSDGVMEELSSGSEDEADAEMGDKCYDVHLNESEMPLGPRLRYKASRMGNRFLAGIDYVGGGLAHLLGITSSKYASELENYHRAKEHGDEDLDNWHPRAMSTTTSSSNNNSSGNNNRNETIVLCEPTRSEATLPPTRQ", "length": 185, "header": "tr|Q9W3S3-1|Q9W3S3_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG8300 PE=1 SV=1 CANONICAL=Q9W3S3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W3S3", "url": "https://www.uniprot.org/uniprotkb/Q9W3S3" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W3S3", "url": "https://www.uniprot.org/uniprotkb/Q9W3S3" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3S3", "url": "https://www.uniprot.org/uniprotkb/Q9W3S3" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3S3", "url": "https://www.uniprot.org/uniprotkb/Q9W3S3" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W3S3", "url": "https://www.uniprot.org/uniprotkb/Q9W3S3" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W3S3", "url": "https://www.uniprot.org/uniprotkb/Q9W3S3" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W3S3", "url": "https://www.uniprot.org/uniprotkb/Q9W3S3" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3S3", "url": "https://www.uniprot.org/uniprotkb/Q9W3S3" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3S3", "url": "https://www.uniprot.org/uniprotkb/Q9W3S3" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W3S3", "url": "https://www.uniprot.org/uniprotkb/Q9W3S3" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W3S3", "url": "https://www.uniprot.org/uniprotkb/Q9W3S3" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG8300", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG8300", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5Y661-1", "protein_name": "Family with sequence similarity 177, member A1", "gene_name": "Fam177a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMDRESGCAATGETEAAAAAAFGDTTRQLSNERGFENVELGVMGKKKKVPRRVIHFVSGETMEEYSTDEDEVDGLDKKDVLPTVDPTKLPWGPYFWFYMLRAATSTLSVCDFLGEKIASVLGISTPKYQYAIDEYYRMKKEEEEEEEENRMSEEAERQYQQNKQQADSMVQTDQPETVVSSSFVNINFEMEEDCEAIKENKQHPVSVPP", "length": 209 }, "evidence": [ { "id": "RGD:2323636", "url": "https://alliancegenome.org/gene/RGD:2323636#orthology", "database": "AGR" }, { "id": "HGNC:19829", "url": "https://alliancegenome.org/gene/HGNC:19829#orthology", "database": "AGR" }, { "id": "MGI:3714351", "url": "https://alliancegenome.org/gene/MGI:3714351#orthology", "database": "AGR" }, { "id": "MGI:1920635", "url": "https://alliancegenome.org/gene/MGI:1920635#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060825-178", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060825-178#orthology", "database": "AGR" }, { "id": "FB:FBgn0029937", "url": "https://alliancegenome.org/gene/FB:FBgn0029937#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M2BFI5-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAKISFFLSSVSITVLQDMEPDKISGKEKEYECVELGDLDRKEKIPRRIIHFSSGETMEEYSTDEEEDNKQNAKKDLLSSRDASNLTLGPYVWFHMWRAATSTISACDYLGERMASLFGITSAKYQYAIDEYSRSKREKEDRNEDTHLSEEAEHLFKEQRNDEDEDLKTDQPETSRHEVQVTNEVHLQSSLVHDTDQIPAVVTCT", "length": 205 }, "evidence": [ { "id": "RGD:2323636", "url": "https://alliancegenome.org/gene/RGD:2323636#orthology", "database": "AGR" }, { "id": "HGNC:19829", "url": "https://alliancegenome.org/gene/HGNC:19829#orthology", "database": 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"id": "FB:FBgn0029937", "url": "https://alliancegenome.org/gene/FB:FBgn0029937#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BR63-1", "protein_name": "Protein FAM177A", "gene_name": "Fam177a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERESGCAAAGETEAAAATAFRDATRQISNERGFENVELGVMGKKKKVPRRVIHFVSGETMEEYSTDEDEVDGLDKKDVLPTVDPTKLTWGPYLWFYMLRAATSTLSVCDFLGEKIASVLGISTPKYQYAIDEYYRMKKEEEEEEEENRMSEEAERQYQQNKLQADSIVQTDQPETVSSSFVNINFEMEEDCEAIKENKQRPVSVPP", "length": 207 }, "evidence": [ { "id": "RGD:2323636", "url": "https://alliancegenome.org/gene/RGD:2323636#orthology", "database": "AGR" }, { "id": "HGNC:19829", "url": "https://alliancegenome.org/gene/HGNC:19829#orthology", "database": "AGR" }, { "id": "MGI:3714351", "url": "https://alliancegenome.org/gene/MGI:3714351#orthology", "database": "AGR" }, { "id": "MGI:1920635", "url": "https://alliancegenome.org/gene/MGI:1920635#orthology", "database": 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"taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W3S4", "url": "https://www.uniprot.org/uniprotkb/Q9W3S4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG4617", "url": "https://www.uniprot.org/uniprotkb/Q9W3S4", "locus": { "chromosome": "X", "start_pos": 7102555, "end_pos": 7104491, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0029936", "url": "https://www.ensemblgenomes.org/id/FBgn0029936" } ] } } ], "crossref": [ { "id": "FB:FBgn0029936", "url": "https://alliancegenome.org/gene/FB:FBgn0029936", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0029936", "url": "https://bgee.org/?page=gene&gene_id=FBgn0029936", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00084", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00084", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0029936", "url": "https://flybase.org/reports/FBgn0029936", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "31657", "url": "https://www.ncbi.nlm.nih.gov/gene/31657", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036910", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036910", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042477", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042477", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG4617", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG4617", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SMGPLLC", "url": "https://omabrowser.org/oma/group/SMGPLLC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W3S4", "url": "https://www.orthodb.org/?gene=Q9W3S4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46584", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46584", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46584:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46584:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "NP_001259308", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001259308", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W3S4", "url": "https://www.uniprot.org/uniprotkb/Q9W3S4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W3S4-1", "url": "https://www.uniprot.org/uniprotkb/Q9W3S4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESPTSHLVAKDFQVTGVSRSGRVRKKSSKLLDFESPDEIEKRTRRHSGARQPARYSGRGRPSNALRDLDLDQEMLVDDGIISDSEEFHPDTTATVVAILNSDDELDNLVQDIVDGVQAEATSQESSVRQSLYMREKSNKRQVLKDGKVVSAKVQRKDKGKQRYTAYSLWAKEARQKDLQDLDFTSATRRLSELWANVSNRDKNTWRRKAKIEASRAKTRDKTAANGATQPASNGSTALADATQHETIFQNRATTSRTRKLAADRQQSSIEAAAAAAAAAATGTNTQRRSISTRSARSQVSKSATKQAQVHTDADVSGRTGGQLKQEEVQKTSIEVIDAAAHLKLLGESLTVIGERLKKHNGYVALSGSLSVLLDSLLCAMGPLLCMTTQIPGMENNVQLSKNLADTLDNIAYVMPGL", "length": 418, "header": "tr|Q9W3S4-1|Q9W3S4_DROME Isoform 1 of HMG box domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG4617 PE=4 SV=2 CANONICAL=Q9W3S4-1" }, "isoforms": [ { "isoform_ac": "Q9W3S4-1", "url": "https://www.uniprot.org/uniprotkb/Q9W3S4/entry#Q9W3S4-1", "sequence": { "sequence": "MESPTSHLVAKDFQVTGVSRSGRVRKKSSKLLDFESPDEIEKRTRRHSGARQPARYSGRGRPSNALRDLDLDQEMLVDDGIISDSEEFHPDTTATVVAILNSDDELDNLVQDIVDGVQAEATSQESSVRQSLYMREKSNKRQVLKDGKVVSAKVQRKDKGKQRYTAYSLWAKEARQKDLQDLDFTSATRRLSELWANVSNRDKNTWRRKAKIEASRAKTRDKTAANGATQPASNGSTALADATQHETIFQNRATTSRTRKLAADRQQSSIEAAAAAAAAAATGTNTQRRSISTRSARSQVSKSATKQAQVHTDADVSGRTGGQLKQEEVQKTSIEVIDAAAHLKLLGESLTVIGERLKKHNGYVALSGSLSVLLDSLLCAMGPLLCMTTQIPGMENNVQLSKNLADTLDNIAYVMPGL", "length": 418, "header": "tr|Q9W3S4-1|Q9W3S4_DROME Isoform 1 of HMG box domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG4617 PE=4 SV=2 CANONICAL=Q9W3S4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W3S4", "url": "https://www.uniprot.org/uniprotkb/Q9W3S4" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W3S4", "url": "https://www.uniprot.org/uniprotkb/Q9W3S4" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3S4", "url": "https://www.uniprot.org/uniprotkb/Q9W3S4" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3S4", "url": "https://www.uniprot.org/uniprotkb/Q9W3S4" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W3S4", "url": "https://www.uniprot.org/uniprotkb/Q9W3S4" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W3S4", "url": "https://www.uniprot.org/uniprotkb/Q9W3S4" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W3S4", "url": "https://www.uniprot.org/uniprotkb/Q9W3S4" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3S4", "url": "https://www.uniprot.org/uniprotkb/Q9W3S4" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3S4", "url": "https://www.uniprot.org/uniprotkb/Q9W3S4" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W3S4", "url": "https://www.uniprot.org/uniprotkb/Q9W3S4" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W3S4", "url": "https://www.uniprot.org/uniprotkb/Q9W3S4" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG4617", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG4617", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M2BB33-1", "protein_name": "HMG domain-containing protein 4a isoform X1", "gene_name": "hmgxb4a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAFEEIRKKGMMDVPGAEGEVSLVAGRSQREKKRSYKDLLREEEEIAAQVCKTSKKHHKDSELFLLGGDSHKKKKKHSSDDYYHRDHHSSGQPPHKKKRKSSDRSPSLTSSSSSHPSHTTDTAMGLLEAITSPLATGSEPPPHLHKKPSYPQHASSHSSKERKRDGSSKNSSHSYPHSRPPGSSSSKKHSSSSSKSLLFHGGAAKGEPLTLCEAEGLKMKLILSSKEKSEGAGVNDFPGQSSSSSSGVAGHHSSSGSKKGGIKKEKDKEKDKMMSKPPKKKQHIREPLPVVGKEVEVEGHYGGSYAGMGGESSSSGGELEAGELVIDDSYTRLSKKKKKSKKSKKKKDKERDRDREKGSREKKHSKGGSGGKKSSQGDQPRSHSHTHSSSNHSSSGGMYPMAPPTSSHQHQSIELIGEKKKKKEEKERDKHDKDKPKKKNMTAYQVFCKEYRVNINAEQPGLVFGELSKKLAEVWKQLPEKDKLVWRQKAQYLQHKQNKAEAMTVKRKTLTTSDSKSKGSSKAFSLGSGLAPQGRSSLGMSLSPARVPDVDPIDAAAHLQLLGESLSLIGHRLQETEGMVAVSGSLSVLLDSILCALGPLTCLTAQVPQLNGCPRNILSNTLDNIAYIMPGL", "length": 632 }, "evidence": [ { "id": "HGNC:5003", "url": "https://alliancegenome.org/gene/HGNC:5003#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-675", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-675#orthology", "database": "AGR" }, { "id": "RGD:1305783", "url": "https://alliancegenome.org/gene/RGD:1305783#orthology", "database": "AGR" }, { "id": "FB:FBgn0029936", "url": "https://alliancegenome.org/gene/FB:FBgn0029936#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABK0LC40-1", "protein_name": "High mobility group protein 2-like 1", "gene_name": "Hmgxb4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSTLRHEITPVKLIVLPASSTPVNAQTEGGADKALLCSSQPLDYLEFPPGRLLLHSDFTLQEGFPCLFLRPGPVDGKEPGHSDTAHSQRPCRTTMAYDDSMKKEDCFDGDHSFEDIGLAAGRSQREKKRSYKDFLREEEEVAAQVRSSSKKKSKDSDLFFLGTDTHKKKRKHSPDDFYYGDISTLESSQKKKKKSSPQSPDTAMDLLKAITSPLAAGAKSSKKAGEKSCSSSSHSESRKEHHKKKGNGSTGEPSLDDSNAHKPKRMKPLYVNTETLTLREPDGLKMRLILSPKEKGSSSVEEEAFQYPAQQASLKKPSKKLAREEQGALLLGHELQSLLKTARKKHKSSSDSHSSPGPEGCGSDGSQLPEPHSANLDITGLDPILVESESSSAGELEAGELVIDDSYREIKKKKKSKKSKKKKDKDRHKEKRHSRTKRSSTREHGTAREHMLVSSPASSIPTLPLPALHTDGHGEKKKKKEEKDRERERGEKPKKKNMSAYQVFCKEYRVTIVADHPGIDFGELSKKLAEVWKQLPEKDKLIWKQKAQYLQHKQNKAEATTVKRKASSAEGTMKVRASSVGILSPQKKSPPTTMLLPASPAKAPETEPIDVAAHLQLLGESLSLIGHRLQETEGMVAVSGSLSVLLDSIICALGPLACLTTQLPELNGCPKQVLSNTLDNIAYIMPGL", "length": 688 }, "evidence": [ { "id": "HGNC:5003", "url": "https://alliancegenome.org/gene/HGNC:5003#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-675", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-675#orthology", "database": "AGR" }, { "id": "RGD:1305783", "url": "https://alliancegenome.org/gene/RGD:1305783#orthology", "database": "AGR" }, { "id": "FB:FBgn0029936", "url": "https://alliancegenome.org/gene/FB:FBgn0029936#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9UGU5-1", "protein_name": "HMG domain-containing protein 4", "gene_name": "HMGXB4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAYDDSVKKEDCFDGDHTFEDIGLAAGRSQREKKRSYKDFLREEEEIAAQVRNSSKKKLKDSELYFLGTDTHKKKRKHSSDDYYYGDISSLESSQKKKKKSSPQSTDTAMDLLKAITSPLAAGSKPSKKTGEKSSGSSSHSESKKEHHRKKVSGSSGELPLEDGGSHKSKKMKPLYVNTETLTLREPDGLKMKLILSPKEKGSSSVDEESFQYPSQQATVKKSSKKSARDEQGALLLGHELQSFLKTARKKHKSSSDAHSSPGPEGCGSDASQFAESHSANLDLSGLEPILVESDSSSGGELEAGELVIDDSYREIKKKKKSKKSKKKKDKEKHKEKRHSKSKRSLGLSAVPVGEVTVTSGPPPSIPYAGAAAPPLPLPGLHTDGHSEKKKKKEEKDKERERGEKPKKKNMSAYQVFCKEYRVTIVADHPGIDFGELSKKLAEVWKQLPEKDKLIWKQKAQYLQHKQNKAEATTVKRKASSSEGSMKVKASSVGVLSPQKKSPPTTMLLPASPAKAPETEPIDVAAHLQLLGESLSLIGHRLQETEGMVAVSGSLSVLLDSIICALGPLACLTTQLPELNGCPKQVLSNTLDNIAYIMPGL", "length": 601 }, "evidence": [ { "id": "HGNC:5003", "url": "https://alliancegenome.org/gene/HGNC:5003#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-675", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-675#orthology", "database": "AGR" }, { "id": "RGD:1305783", "url": "https://alliancegenome.org/gene/RGD:1305783#orthology", "database": "AGR" }, { "id": "FB:FBgn0029936", "url": "https://alliancegenome.org/gene/FB:FBgn0029936#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q9W3S4", "url": "https://www.uniprot.org/uniprotkb/Q9W3S4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9W3S4", "url": "https://www.uniprot.org/uniprotkb/Q9W3S4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 197, "end_pos": 199, "annotation": "n_glycosylation_sequon" }, { "start_pos": 234, "end_pos": 236, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9W3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3S4" }, { "id": "PS50118", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50118" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HMG box", "eco_id": "ECO_0000259", "start_pos": 160, "end_pos": 211, "start_aa": "Gly", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 197, "end_pos": 199 }, { "start_pos": 234, "end_pos": 236 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9W3S8-1", "uniprot_ac": "Q9W3S8", "uniprot_id": "Q9W3S8_DROME", "mass": { "chemical_mass": 58133.0, "monoisotopic_mass": 58133.0 }, "refseq": { "ac": "NP_572380", "name": "uncharacterized protein, isoform A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572380" }, "gene_names": [ { "name": "Dmel\\CG4607", "type": "recommended", "evidence": [ { "id": "Q9W3S8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3S8" } ] }, { "name": "CG4607", "type": "synonym", "evidence": [ { "id": "NP_572380", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572380" }, { "id": "Q9W3S8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3S8" } ] }, { "name": "Dmel\\CG4607", "type": "synonym", "evidence": [ { "id": "NP_572380", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572380" } ] }, { "name": "Dmel_CG4607", "type": "synonym", "evidence": [ { "id": "Q9W3S8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3S8" } ] } ], "protein_names": [ { "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "Q9W3S8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3S8/entry#names_and_taxonomy" } ] }, { "name": "CG4607-PA", "type": "synonym", "evidence": [ { "id": "NP_572380", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572380" } ] }, { "name": "uncharacterized protein, isoform A", "type": "synonym", "evidence": [ { "id": "NP_572380", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572380" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W3S8", "url": "https://www.uniprot.org/uniprotkb/Q9W3S8" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG4607", "url": "https://www.uniprot.org/uniprotkb/Q9W3S8", "locus": { "chromosome": "X", "start_pos": 7072689, "end_pos": 7069413, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0029932", "url": "https://www.ensemblgenomes.org/id/FBgn0029932" } ] } } ], "crossref": [ { "id": "FB:FBgn0029932", "url": "https://alliancegenome.org/gene/FB:FBgn0029932", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0029932", "url": "https://bgee.org/?page=gene&gene_id=FBgn0029932", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17358", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17358", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0029932", "url": "https://flybase.org/reports/FBgn0029932", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "31653", "url": "https://www.ncbi.nlm.nih.gov/gene/31653", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003663", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003663", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005829", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005829", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050549", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050549", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG4607", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG4607", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "INNMACP", "url": "https://omabrowser.org/oma/group/INNMACP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W3S8", "url": "https://www.orthodb.org/?gene=Q9W3S8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48021", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48021", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48021:SF89", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48021:SF89", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00083", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00083", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-189200", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-189200", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_572380", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572380", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W3S8", "url": "https://www.uniprot.org/uniprotkb/Q9W3S8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W3S8-1", "url": "https://www.uniprot.org/uniprotkb/Q9W3S8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKGQQEEQLVPPPAYKPTVVAKDTTKDSHAKEKPLGEGRLAVLRQELMVFLGNSGVLGSGMVVSMPAVTLNQLHDETQPFWLNKDESSWFASIQNMACPLGGLLVSYFLDRIGRKHTILLTNLIGLIGWILLVTSFMHSDRDMIYYQMLLGRCFGGIMIGMFVSPVGVYSAEISLPKIRGRLILGTSLGLASGILLMYCLGYFIRHNIQLIFGISCCYQLAATLLVFPMPESPSWLLTRGKEERARKSLRYFRGLPKKEVDYVPEFEAELAHMKELADASNTTAAGESLSQMIHRPEVYKPVLMMTTFFGFQQACGVVVIIVYAVQIAQQAGVTIDPVLVAVMLGVARIITTLFMSGIFEKWGRKPSGIFSATGMGACMLLLAGGNWFPDTLGTLHWLPVACIVAHIVFSTMGMLTLPFFMISEVFPQRARGSASGIAIFFGMILAFIMLKIYPNMEAALGTANLFAFYAGISFLAAAFIGVFVPETRGRTLEELEERWQTGKFSRRLTIVNLKDVELHEVFLKK", "length": 525, "header": "tr|Q9W3S8-1|Q9W3S8_DROME Isoform 1 of Major facilitator superfamily (MFS) profile domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG4607 PE=4 SV=1 CANONICAL=Q9W3S8-1" }, "isoforms": [ { "isoform_ac": "Q9W3S8-1", "url": "https://www.uniprot.org/uniprotkb/Q9W3S8/entry#Q9W3S8-1", "sequence": { "sequence": "MKGQQEEQLVPPPAYKPTVVAKDTTKDSHAKEKPLGEGRLAVLRQELMVFLGNSGVLGSGMVVSMPAVTLNQLHDETQPFWLNKDESSWFASIQNMACPLGGLLVSYFLDRIGRKHTILLTNLIGLIGWILLVTSFMHSDRDMIYYQMLLGRCFGGIMIGMFVSPVGVYSAEISLPKIRGRLILGTSLGLASGILLMYCLGYFIRHNIQLIFGISCCYQLAATLLVFPMPESPSWLLTRGKEERARKSLRYFRGLPKKEVDYVPEFEAELAHMKELADASNTTAAGESLSQMIHRPEVYKPVLMMTTFFGFQQACGVVVIIVYAVQIAQQAGVTIDPVLVAVMLGVARIITTLFMSGIFEKWGRKPSGIFSATGMGACMLLLAGGNWFPDTLGTLHWLPVACIVAHIVFSTMGMLTLPFFMISEVFPQRARGSASGIAIFFGMILAFIMLKIYPNMEAALGTANLFAFYAGISFLAAAFIGVFVPETRGRTLEELEERWQTGKFSRRLTIVNLKDVELHEVFLKK", "length": 525, "header": "tr|Q9W3S8-1|Q9W3S8_DROME Isoform 1 of Major facilitator superfamily (MFS) profile domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG4607 PE=4 SV=1 CANONICAL=Q9W3S8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W3S8", "url": "https://www.uniprot.org/uniprotkb/Q9W3S8" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W3S8", "url": "https://www.uniprot.org/uniprotkb/Q9W3S8" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3S8", "url": "https://www.uniprot.org/uniprotkb/Q9W3S8" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3S8", "url": "https://www.uniprot.org/uniprotkb/Q9W3S8" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W3S8", "url": "https://www.uniprot.org/uniprotkb/Q9W3S8" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W3S8", "url": "https://www.uniprot.org/uniprotkb/Q9W3S8" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W3S8", "url": "https://www.uniprot.org/uniprotkb/Q9W3S8" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3S8", "url": "https://www.uniprot.org/uniprotkb/Q9W3S8" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3S8", "url": "https://www.uniprot.org/uniprotkb/Q9W3S8" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W3S8", "url": "https://www.uniprot.org/uniprotkb/Q9W3S8" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W3S8", "url": "https://www.uniprot.org/uniprotkb/Q9W3S8" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG4607", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG4607", "resource": "KEGG Pathway" }, { "id": "R-DME-189200", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-189200", "resource": "Reactome", "description": "Cellular hexose transport" } ], "orthologs": [ { "uniprot_canonical_ac": "A1Z8N1-1", "protein_name": "Trehalose transporter 1", "gene_name": "Tret1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSGRDNRGAGGGGGGHQPLSNAMGKLKEKLTRVGDELGYHRVESNLSTSNTATSLDTILPEDPFLFPQVSPQRHPQNTVRTQRLLEDEPPLSFRPLLEDDDINEPPTQQQQRTPLRASGSLELTPLPPPPTSLEIREHRDRQQRGAQGDELQRSKQSLKGSRVSFERRDTGNSNTNSNKAAESSDEDSFEEKRTGFQQQKATSVDHKGILKDLKHILANDNRRQFQAKKHVSLDVKGTRFLQDLLKESSSEEEFHKTRREFQGRKHQSLDPRVTFKLDKVLQGSSTDSDEEGEDAEHKRLIHRPKDITKPVIIDLKDLESESDEDFLTSRQHFQQQRSISTDSRKSRRLYEMDEMDNKRGENIRHAVPFVRQITEDGKPKLEVYRPTTNPIYIWTQVLAALSVSLGSLVVGFVSAYTSPALVSMTDRNITSFEVTQDAGSWVGGIMPLAGLAGGIAGGPLIEYLGRRNTILATAVPFIVSSLLIACAVNVAMVLCGRFLAGFCVGIASLSLPVYLGETVQPEVRGTLGLLPTAFGNIGILLCFVAGSFMNWSMLAFLGAALPVPFLILMFLIPETPRWFVGRGLEERARKALKWLRGKEADVEPELKGLMRSQADADRQASRNTMLELLKLNNLKPLSISLGLMFFQQFSGINAVIFYTVQIFKDAGSTIDGNLCTIIVGIVNFLATFIGIVLIDRAGRKILLYVSDIAMVLTLFVLGGFFYCKTYGPDVSHLGWLPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGSAASVATAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICFVGLFFVIIYVPETQGKTLEDIERKMMGRVRRMSSVANIKPLSFNM", "length": 857 }, "evidence": [ { "id": "RGD:620611", "url": "https://alliancegenome.org/gene/RGD:620611#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A8JQU1-1", "protein_name": "Major facilitator superfamily (MFS) profile domain-containing protein", "gene_name": "Dmel\\CG1208", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDSEKVVRAMARWWQTVSQEDGDSRNPITYDLLQENQSKTSKTRQYVAAMIICLGAVAAGTALSWTSPVFPQISAGNESSFNSTTGGISNSTSNENDIRLTDSQKTLVGSMLPFGALFGALPSGYIADRIGRRYTAMVMDIPFILAWITLSFANSVGWLYLGRFLIGIATGSFCVVAPMYISEIAETSIRGSLGTLFQLLLTIGILFIYVVGALVSWKTLSLLCLIIPILLLVGLFIVPETPVYLLKNGKRSEANRALKWLWGDYCNTSNAIQAIQNDLDQTGVDASVKDLFSNRASRNGMVISVLLMVFQQFSGINAVIFFMNEIFESSSTLNPNVCTIVVGVVQVIMTLASSLLIEKAGRKILLIFSSTIMTVCLAMLGAYNTINRHTDLSQSIGWLPLLCIVLFIVSFSVGYGPIPWMMMGELFMPDVKGIAVSLSVMMNWVCVSLVTWLFGVLNAGGADVPFWFFSAWMGVATAYVAIALQETKGKSASQIQSWLSGR", "length": 502 }, "evidence": [ { "id": "RGD:620611", "url": "https://alliancegenome.org/gene/RGD:620611#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P13181-1", "protein_name": "Galactose transporter", "gene_name": "GAL2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAVEENNMPVVSQQPQAGEDVISSLSKDSHLSAQSQKYSNDELKAGESGSEGSQSVPIEIPKKPMSEYVTVSLLCLCVAFGGFMFGWDTGTISGFVVQTDFLRRFGMKHKDGTHYLSNVRTGLIVAIFNIGCAFGGIILSKGGDMYGRKKGLSIVVSVYIVGIIIQIASINKWYQYFIGRIISGLGVGGIAVLCPMLISEIAPKHLRGTLVSCYQLMITAGIFLGYCTNYGTKSYSNSVQWRVPLGLCFAWSLFMIGALTLVPESPRYLCEVNKVEDAKRSIAKSNKVSPEDPAVQAELDLIMAGIEAEKLAGNASWGELFSTKTKVFQRLLMGVFVQMFQQLTGNNYFFYYGTVIFKSVGLDDSFETSIVIGVVNFASTFFSLWTVENLGHRKCLLLGAATMMACMVIYASVGVTRLYPHGKSQPSSKGAGNCMIVFTCFYIFCYATTWAPVAWVITAESFPLRVKSKCMALASASNWVWGFLIAFFTPFITSAINFYYGYVFMGCLVAMFFYVFFFVPETKGLSLEEIQELWEEGVLPWKSEGWIPSSRRGNNYDLEDLQHDDKPWYKAMLE", "length": 574 }, "evidence": [ { "id": "RGD:620611", "url": "https://alliancegenome.org/gene/RGD:620611#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P23585-1", "protein_name": "High-affinity glucose transporter HXT2", "gene_name": "HXT2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSEFATSRVESGSQQTSIHSTPIVQKLETDESPIQTKSEYTNAELPAKPIAAYWTVICLCLMIAFGGFVFGWDTGTISGFVNQTDFKRRFGQMKSDGTYYLSDVRTGLIVGIFNIGCAFGGLTLGRLGDMYGRRIGLMCVVLVYIVGIVIQIASSDKWYQYFIGRIISGMGVGGIAVLSPTLISETAPKHIRGTCVSFYQLMITLGIFLGYCTNYGTKDYSNSVQWRVPLGLNFAFAIFMIAGMLMVPESPRFLVEKGRYEDAKRSLAKSNKVTIEDPSIVAEMDTIMANVETERLAGNASWGELFSNKGAILPRVIMGIMIQSLQQLTGNNYFFYYGTTIFNAVGMKDSFQTSIVLGIVNFASTFVALYTVDKFGRRKCLLGGSASMAICFVIFSTVGVTSLYPNGKDQPSSKAAGNVMIVFTCLFIFFFAISWAPIAYVIVAESYPLRVKNRAMAIAVGANWIWGFLIGFFTPFITSAIGFSYGYVFMGCLVFSFFYVFFFVCETKGLTLEEVNEMYVEGVKPWKSGSWISKEKRVSEE", "length": 541 }, "evidence": [ { "id": "RGD:620611", "url": "https://alliancegenome.org/gene/RGD:620611#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P32465-1", "protein_name": "Low-affinity glucose transporter HXT1", "gene_name": "HXT1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MNSTPDLISPQKSNSSNSYELESGRSKAMNTPEGKNESFHDNLSESQVQPAVAPPNTGKGVYVTVSICCVMVAFGGFIFGWDTGTISGFVAQTDFLRRFGMKHHDGSHYLSKVRTGLIVSIFNIGCAIGGIVLAKLGDMYGRRIGLIVVVVIYTIGIIIQIASINKWYQYFIGRIISGLGVGGITVLSPMLISEVAPSEMRGTLVSCYQVMITLGIFLGYCTNFGTKNYSNSVQWRVPLGLCFAWALFMIGGMMFVPESPRYLVEAGRIDEARASLAKVNKCPPDHPYIQYELETIEASVEEMRAAGTASWGELFTGKPAMFQRTMMGIMIQSLQQLTGDNYFFYYGTIVFQAVGLSDSFETSIVFGVVNFFSTCCSLYTVDRFGRRNCLMWGAVGMVCCYVVYASVGVTRLWPNGQDQPSSKGAGNCMIVFACFYIFCFATTWAPIAYVVISECFPLRVKSKCMSIASAANWIWGFLISFFTPFITGAINFYYGYVFMGCMVFAYFYVFFFVPETKGLSLEEVNDMYAEGVLPWKSASWVPVSKRGADYNADDLMHDDQPFYKSLFSRK", "length": 570 }, "evidence": [ { "id": "RGD:620611", "url": "https://alliancegenome.org/gene/RGD:620611#orthology", "database": "AGR" }, { "id": "Q9W3S8", "url": "https://omabrowser.org/oma/group/Q9W3S8/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P32466-1", "protein_name": "Low-affinity glucose transporter HXT3", "gene_name": "HXT3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MNSTPDLISPQKSSENSNADLPSNSSQVMNMPEEKGVQDDFQAEADQVLTNPNTGKGAYVTVSICCVMVAFGGFVFGWDTGTISGFVAQTDFLRRFGMKHKDGSYYLSKVRTGLIVSIFNIGCAIGGIILAKLGDMYGRKMGLIVVVVIYIIGIIIQIASINKWYQYFIGRIISGLGVGGIAVLSPMLISEVAPKEMRGTLVSCYQLMITLGIFLGYCTNFGTKNYSNSVQWRVPLGLCFAWALFMIGGMTFVPESPRYLVEAGQIDEARASLSKVNKVAPDHPFIQQELEVIEASVEEARAAGSASWGELFTGKPAMFKRTMMGIMIQSLQQLTGDNYFFYYGTTVFNAVGMSDSFETSIVFGVVNFFSTCCSLYTVDRFGRRNCLLYGAIGMVCCYVVYASVGVTRLWPNGEGNGSSKGAGNCMIVFACFYIFCFATTWAPIAYVVISETFPLRVKSKAMSIATAANWLWGFLIGFFTPFITGAINFYYGYVFMGCMVFAYFYVFFFVPETKGLTLEEVNDMYAEGVLPWKSASWVPTSQRGANYDADALMHDDQPFYKKMFGKK", "length": 567 }, "evidence": [ { "id": "RGD:620611", "url": "https://alliancegenome.org/gene/RGD:620611#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P32467-1", "protein_name": "Low-affinity glucose transporter HXT4", "gene_name": "HXT4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSEEAAYQEDTAVQNTPADALSPVESDSNSALSTPSNKAERDDMKDFDENHEESNNYVEIPKKPASAYVTVSICCLMVAFGGFVFGWDTGTISGFVAQTDFIRRFGMKHHDGTYYLSKVRTGLIVSIFNIGCAIGGIILAKLGDMYGRKMGLIVVVVIYIIGIIIQIASINKWYQYFIGRIISGLGVGGIAVLSPMLISEVSPKHIRGTLVSCYQLMITLGIFLGYCTNYGTKTYTNSVQWRVPLGLGFAWALFMIGGMTFVPESPRYLVEVGKIEEAKRSIALSNKVSADDPAVMAEVEVVQATVEAEKLAGNASWGEIFSTKTKVFQRLIMGAMIQSLQQLTGDNYFFYYGTTVFTAVGLEDSFETSIVLGIVNFASTFVGIFLVERYGRRRCLLWGAASMTACMVVFASVGVTRLWPNGKKNGSSKGAGNCMIVFTCFYLFCFATTWAPIPFVVNSETFPLRVKSKCMAIAQACNWIWGFLIGFFTPFISGAIDFYYGYVFMGCLVFSYFYVFFFVPETKGLTLEEVNTLWEEGVLPWKSPSWVPPNKRGTDYNADDLMHDDQPFYKKMFGKK", "length": 576 }, "evidence": [ { "id": "RGD:620611", "url": "https://alliancegenome.org/gene/RGD:620611#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P38695-1", "protein_name": "Probable glucose transporter HXT5", "gene_name": "HXT5", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSELENAHQGPLEGSATVSTNSNSYNEKSGNSTAPGTAGYNDNLAQAKPVSSYISHEGPPKDELEELQKEVDKQLEKKSKSDLLFVSVCCLMVAFGGFVFGWDTGTISGFVRQTDFIRRFGSTRANGTTYLSDVRTGLMVSIFNIGCAIGGIVLSKLGDMYGRKIGLMTVVVIYSIGIIIQIASIDKWYQYFIGRIISGLGVGGITVLAPMLISEVSPKQLRGTLVSCYQLMITFGIFLGYCTNFGTKNYSNSVQWRVPLGLCFAWSIFMIVGMTFVPESPRYLVEVGKIEEAKRSLARANKTTEDSPLVTLEMENYQSSIEAERLAGSASWGELVTGKPQMFRRTLMGMMIQSLQQLTGDNYFFYYGTTIFQAVGLEDSFETAIVLGVVNFVSTFFSLYTVDRFGRRNCLLWGCVGMICCYVVYASVGVTRLWPNGQDQPSSKGAGNCMIVFACFYIFCFATTWAPVAYVLISESYPLRVRGKAMSIASACNWIWGFLISFFTPFITSAINFYYGYVFMGCMVFAYFYVFFFVPETKGLTLEEVNEMYEENVLPWKSTKWIPPSRRTTDYDLDATRNDPRPFYKRMFTKEK", "length": 592 }, "evidence": [ { "id": "RGD:620611", "url": "https://alliancegenome.org/gene/RGD:620611#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P39003-1", "protein_name": "High-affinity hexose transporter HXT6", "gene_name": "HXT6", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSQDAAIAEQTPVEHLSAVDSASHSVLSTPSNKAERDEIKAYGEGEEHEPVVEIPKRPASAYVTVSIMCIMIAFGGFVFGWDTGTISGFINQTDFIRRFGMKHKDGTNYLSKVRTGLIVSIFNIGCAIGGIILSKLGDMYGRKVGLIVVVVIYIIGIIIQIASINKWYQYFIGRIISGLGVGGIAVLSPMLISEVSPKHLRGTLVSCYQLMITAGIFLGYCTNFGTKNYSNSVQWRVPLGLCFAWALFMIGGMTFVPESPRYLAEVGKIEEAKRSIAVSNKVAVDDPSVLAEVEAVLAGVEAEKLAGNASWGELFSSKTKVLQRLIMGAMIQSLQQLTGDNYFFYYGTTIFKAVGLSDSFETSIVLGIVNFASTFVGIYVVERYGRRTCLLWGAASMTACMVVYASVGVTRLWPNGQDQPSSKGAGNCMIVFACFYIFCFATTWAPIPYVVVSETFPLRVKSKAMSIATAANWLWGFLIGFFTPFITGAINFYYGYVFMGCLVFMFFYVLLVVPETKGLTLEEVNTMWEEGVLPWKSASWVPPSRRGANYDAEEMAHDDKPLYKRMFSTK", "length": 570 }, "evidence": [ { "id": "RGD:620611", "url": "https://alliancegenome.org/gene/RGD:620611#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P39004-1", "protein_name": "High-affinity hexose transporter HXT7", "gene_name": "HXT7", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSQDAAIAEQTPVEHLSAVDSASHSVLSTPSNKAERDEIKAYGEGEEHEPVVEIPKRPASAYVTVSIMCIMIAFGGFVFGWDTGTISGFINQTDFIRRFGMKHKDGTNYLSKVRTGLIVSIFNIGCAIGGIILSKLGDMYGRKVGLIVVVVIYIIGIIIQIASINKWYQYFIGRIISGLGVGGIAVLSPMLISEVSPKHLRGTLVSCYQLMITAGIFLGYCTNFGTKNYSNSVQWRVPLGLCFAWALFMIGGMTFVPESPRYLAEVGKIEEAKRSIAVSNKVAVDDPSVLAEVEAVLAGVEAEKLAGNASWGELFSSKTKVLQRLIMGAMIQSLQQLTGDNYFFYYGTTIFKAVGLSDSFETSIVLGIVNFASTFVGIYVVERYGRRTCLLWGAASMTACMVVYASVGVTRLWPNGQDQPSSKGAGNCMIVFACFYIFCFATTWAPIPYVVVSETFPLRVKSKAMSIATAANWLWGFLIGFFTPFITGAINFYYGYVFMGCLVFMFFYVLLVVPETKGLTLEEVNTMWEEGVLPWKSASWVPPSRRGANYDAEEMTHDDKPLYKRMFSTK", "length": 570 }, "evidence": [ { "id": "RGD:620611", "url": "https://alliancegenome.org/gene/RGD:620611#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P39924-1", "protein_name": "Hexose transporter HXT13", "gene_name": "HXT13", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSSAQSSIDSDGDVRDADIHVAPPVEKEWSDGFDDNEVINGDNVEPPKRGLIGYLVIYLLCYPISFGGFLPGWDSGITAGFINMDNFKMNFGSYKHSTGEYYLSNVRMGLLVAMFSIGCAIGGLIFARLADTLGRRLAIVIVVLVYMVGAIIQISSNHKWYQYFVGKIIYGLGAGGCSVLCPMLLSEIAPTDLRGGLVSLYQLNMTFGIFLGYCSVYGTRKYDNTAQWRVPLGLCFLWALIIIIGMLLVPESPRYLIECERHEEARASIAKINKVSPEDPWVLKQADEINAGVLAQRELGEASWKELFSVKTKVLQRLITGILVQTFLQLTGENYFFFYGTTIFKSVGLTDGFETSIVLGTVNFFSTIIAVMVVDKIGRRKCLLFGAAGMMACMVIFASIGVKCLYPHGQDGPSSKGAGNAMIVFTCFYIFCFATTWAPVAYIVVAESFPSKVKSRAMSISTACNWLWQFLIGFFTPFITGSIHFYYGYVFVGCLVAMFLYVFFFLPETIGLSLEEIQLLYEEGIKPWKSASWVPPSRRGISSEESKTEKKDWKKFLKFSKNSD", "length": 564 }, "evidence": [ { "id": "RGD:620611", "url": "https://alliancegenome.org/gene/RGD:620611#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P40885-1", "protein_name": "Hexose transporter HXT9", "gene_name": "HXT9", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSGVNNTSANDLSTTESNSNSVANAPSVKTEHNDSKNSLNLDATEPPIDLPQKPLSAYTTVAILCLMIAFGGFIFGWDTGTISGFVNLSDFIRRFGQKNDKGTYYLSKVRMGLIVSIFNIGCAIGGIVLSKVGDIYGRRIGLITVTAIYVVGILIQITSINKWYQYFIGRIISGLGVGGIAVLSPMLISEVAPKQIRGTLVQLYQLMCTMGIFLGYCTNYGTKNYHNATQWRVGLGLCFAWTTFMVSGMMFVPESPRYLIEVGKDEEAKRSLSKSNKVSVDDPALLAEYDTIKAGIELEKLAGNASWSELLSTKTKVFQRVLMGVMIQSLQQLTGDNYFFYYGTTIFKSVGLKDSFQTSIIIGVVNFFSSFIAVYTIERFGRRTCLLWGAASMLCCFAVFASVGVTKLWPQGSSHQDITSQGAGNCMIVFTMFFIFSFATTWAGGCYVIVSETFPLRVKSRGMAIATAANWMWGFLISFFTPFITGAINFYYGYVFLGCLVFAYFYVFFFVPETKGLTLEEVNTMWLEGVPAWKSASWVPPERRTADYDADAIDHDDRPIYKRFFSS", "length": 567 }, "evidence": [ { "id": "RGD:620611", "url": "https://alliancegenome.org/gene/RGD:620611#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P40886-1", "protein_name": "Hexose transporter HXT8", "gene_name": "HXT8", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTDRKTNLPEEPIFEEAEDDGCPSIENSSHLSVPTVEENKDFSEYNGEEAEEVVVPEKPASAYATVSIMCLCMAFGGFMSGWDTGTISGFVNQTDFLRRFGNYSHSKNTYYLSNVRTGLIVSIFNVGSAIGCLFLSKLGDIYGRCMGLIIVIVVYMVGIVIQIASIDKWYQYFIGRIIAGIGAGSISVLAPMLISETAPKHIRGTLLACWQLMVTFAIFLGYCTNYGTKTYSNSVQWRVPLGLCFAWAIIMIGGMTFVPESPRFLVQVGKIEQAKASFAKSNKLSVDDPAVVAEIDLLVAGVEAEEAMGTASWKELFSRKTKVFQRLTMTVMINSLQQLTGDNYFFYYGTTIFKSVGMNDSFETSIVLGIVNFASCFFSLYSVDKLGRRRCLLLGAATMTACMVIYASVGVTRLYPNGKSEPSSKGAGNCTIVFTCFYIFCFSCTWGPVCYVIISETFPLRVRSKCMSVATAANLLWGFLIGFFTPFITSAINFYYGYVFMGCLAFSYFYVFFFVPETKGLTLEEVDEMWMDGVLPWKSESWVPASRRDGDYDNEKLQHDEKPFYKRMF", "length": 569 }, "evidence": [ { "id": "RGD:620611", "url": "https://alliancegenome.org/gene/RGD:620611#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P43581-1", "protein_name": "Hexose transporter HXT10", "gene_name": "HXT10", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVSSSVSILGTSAKASTSLSRKDEIKLTPETREASLDIPYKPIIAYWTVMGLCLMIAFGGFIFGWDTGTISGFINQTDFKRRFGELQRDGSFQLSDVRTGLIVGIFNIGCALGGLTLGRLGDIYGRKIGLMCVILVYVVGIVIQIASSDKWYQYFIGRIVSGMGVGGVAVLSPTLISEISPKHLRGTCVSFYQLMITLGIFLGYCTNYGTKKYSNSIQWRVPLGLCFAWAIFMVIGMVMVPESPRYLVEKGKYEEARRSLAKSNKVTVTDPGVVFEFDTIVANMELERAVGNASWHELFSNKGAILPRVIMGIVIQSLQQLTGCNYFFYYGTTIFNAVGMQDSFETSIVLGAVNFASTFVALYIVDKFGRRKCLLWGSASMAICFVIFATVGVTRLWPQGKDQPSSQSAGNVMIVFTCFFIFSFAITWAPIAYVIVAETYPLRVKNRAMAIAVGANWMWGFLIGFFTPFITRSIGFSYGYVFMGCLIFSYFYVFFFVCETKGLTLEEVNEMYEERIKPWKSGGWIPSSRRTPQPTSSTPLVIVDSK", "length": 546 }, "evidence": [ { "id": "RGD:620611", "url": "https://alliancegenome.org/gene/RGD:620611#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P47185-1", "protein_name": "Hexose transporter HXT16", "gene_name": "HXT16", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MASEQSSPEINADNLNSSAADVHVQPPGEKEWSDGFYDKEVINGNTPDAPKRGFLGYLIIYLLCYPVSFGGFLPGWDSGITAGFINMDNFKMNFGSYKHSTGEYYLSNVRMGLLVAMFSVGCSIGGVAFARLADTLGRRLAIVIVVLVYMVGAIIQISSNHKWYQYFVGKIIYGLGAGGCSVLCPMLLSEIAPTDLRGGLVSLYQLNMTFGIFLGYCSVYGTRKYSNTAQWRIPVGLCFLWALIIIVGMLLVPESPRYLIECERHEEACVSIAKIDKVSPEDPWVLKQADEINAGVLAQRELGEASWKELFSVKTKVLQRLITGILVQTFLQLTGENYFFFYGTTIFKSVGLTDGFETSIVLGTVNFFSTIIAVMVVDKIGRRKCLLFGAASMMACMVIFASIGVKCLYPHGQDGPSSKGAGNAMIVFTCFYIFCFATTWAPVAYIVVAESFPSKVKSKAMSISTAFNWLWQFLIGFFTPFITGSIHFYYGYVFVGCLVAMFLYVFFFLPETIGLSLEETQLLYEEGIKPWKSASWVPPSRRGASSRETEAKKKSWKEVLKFPKSFN", "length": 567 }, "evidence": [ { "id": "RGD:620611", "url": "https://alliancegenome.org/gene/RGD:620611#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P53403-1", "protein_name": "Glucose transporter type 3", "gene_name": "Glut3", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRKGGIQDAEPVEPPQSSRKSGTWFAKRPSEMPERHVERAPVRQKINNVGLYKATLYSNIGSFFFGIAVGWSGTAERSVMEQHSYSFQPTELQWSGVCILLTLGAALWCLPMGLMVRLLGCRRTILIQLLPNFLGWFLTVFARSVPMLYAGRFFLGMCGGAHCVVVPIYNAEISTTKKRGAMGVVFEGACICGVIYSFAMSLFLELRIINFVNLGLLALGPLQILMPESPAYYVDHGNIPRAEDSLRFLRGQKYDTRREIDFLTRDPTESEREVRQGPLLGFKYKKVRRSLARSLAIALLQKLCGALIFIFYGLNMLDCLRIRREFGLILCLGLILGFLACFFLVDRLGRRPLLIFSSAGIVFVSIYLGLHFKVWMTMGLTVMSWIALFCIAIFVGCYTAGVGSLTWVLNAELLVRPMRPLGCSIVCAFNWLTAFFVICWFGSHGVKCQPYLFLLFAIIASLILLFSLIYIPETKKLSSAKIQQRLGGLINRPAVITFTSSSDSSNA", "length": 507 }, "evidence": [ { "id": "RGD:620611", "url": "https://alliancegenome.org/gene/RGD:620611#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P53631-1", "protein_name": "Hexose transporter HXT17", "gene_name": "HXT17", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MQSSTESDRDIQDGPDADIHVAPPVEKEWSDGFDDNEVINGDNVEPPKRGLIGYLVIYLLCYPISFGGFLPGWDSGITAGFINMDNFKMNFGSYKHSTGEYYLSNVRMGLLVAMFSIGCAIGGLIFARLADTLGRRLAIVIVVLVYMVGAIIQISSNHKWYQYFVGKIIYGLGAGGCSVLCPMLLSEIAPTDLRGGLVSLYQLNMTFGIFLGYCSVYGTRKYDNTAQWRVPLGLCFLWTLIIIIGMLLVPESPRYLIECERHEEARASIAKINKVSPEDPWVLKQADEINAGVLAQRELGEASWKELFSVKTKVLQRLITGILVQTFLQLTGENYFFFYGTTIFKSVGLTDGFETSIVLGTVNFFSTIIAVMVVDKIGRRKCLLFGAAGMMACMVIFASIGVKCLYPHGQDGPSSKGAGNAMIVFTCFYIFCFATTWAPVAYIVVAESFPSKVKSRAMSISTACNWLWQFLIGFFTPFITGSIHFYYGYVFVGCLVAMFLYVFFFLPETIGLSLEEIQLLYEEGIKPWKSASWVPPSRRGIPSEESKTEKKDWKKFLKFSKGSD", "length": 564 }, "evidence": [ { "id": "RGD:620611", "url": "https://alliancegenome.org/gene/RGD:620611#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P54854-1", "protein_name": "Hexose transporter HXT15", "gene_name": "HXT15", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MASEQSSPEINADNLNSSAADVHVQPPGEKEWSDGFYDKEVINGNTPDAPKRGFLGYLIIYLLCYPVSFGGFLPGWDSGITAGFINMDNFKMNFGSYKHSTGEYYLSNVRMGLLVAMFSVGCSIGGVAFARLADTLGRRLAIVIVVLVYMVGAIIQISSNHKWYQYFVGKIIYGLGAGGCSVLCPMLLSEIAPTDLRGGLVSLYQLNMTFGIFLGYCSVYGTRKYSNTAQWRIPVGLCFLWALIIIVGMLLVPESPRYLIECERHEEACVSIAKINKVSPEDPWVLKQADEINAGVLAQRELGEASWKELFSVKTKVLQRLITGILVQTFLQLTGENYFFFYGTTIFKSVGLTDGFETSIVLGTVNFFSTIIAVMVVDKIGRRKCLLFGAASMMACMVIFASIGVKCLYPHGQDGPSSKGAGNAMIVFTCFYIFCFATTWAPVAYIVVAESFPSKVKSKAMSISTAFNWLWQFLIGFFTPFITGSIHFYYGYVFVGCLVAMFLYVFFFLPETIGLSLEEIQLLYEEGIKPWKSASWVPPSRRGASSRETEAKKKSWKEVLKFPKSFN", "length": 567 }, "evidence": [ { "id": "RGD:620611", "url": "https://alliancegenome.org/gene/RGD:620611#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P54862-1", "protein_name": "Hexose transporter HXT11", "gene_name": "HXT11", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSGVNNTSANELSTTMSNSNSAVGAPSVKTEHGDSKNSLNLDANEPPIDLPQKPLSAYTTVAILCLMIAFGGFIFGWDTGTISGFVNLSDFIRRFGQKNDKGTYYLSKVRMGLIVSIFNIGCAIGGIVLSKVGDIYGRRIGLITVTAIYVVGILIQITSINKWYQYFIGRIISGLGVGGIAVLSPMLISEVAPKHIRGTLVQLYQLMGTMGIFLGYCTNYGTKNYHNATQWRVGLGLCFAWATFMVSGMMFVPESPRYLIEVGKDEEAKRSLSKSNKVSVDDPALLVEYDTIKAGIELEKLAGNASWSELLSTKTKVFQRVLMGVMIQSLQQLTGDNYFFYYGTTIFKSVGLKDSFQTSIIIGVVNFFSSFIAVYTIERFGRRTCLLWGAASMLCCFAVFASVGVTKLWPQGSSHQDITSQGAGNCMIVFTMFFIFSFATTWAGGCYVIVSETFPLRVKSRGMAIATAANWMWGFLISFFTPFITGAINFYYGYVFLGCLVFAYFYVFFFVPETKGLTLEEVNTMWLEGVPAWKSASWVPPERRTADYDADAIDHDNRPIYKRFFSS", "length": 567 }, "evidence": [ { "id": "RGD:620611", "url": "https://alliancegenome.org/gene/RGD:620611#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q8L7R8-1", "protein_name": "Sugar transport protein 3", "gene_name": "STP3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVAEEARKEAMAKSVSGGKITYFVVASCVMAAMGGVIFGYDIGVSGGVMSMGPFLKRFFPKVYKLQEEDRRRRGNSNNHYCLFNSQLLTSFTSSLYVSGLIATLLASSVTRSWGRKPSIFLGGVSFLAGAALGGSAQNVAMLIIARLLLGVGVGFANQSVPLYLSEMAPAKYRGAISNGFQLCIGIGFLSANVINYETQNIKHGWRISLATAAIPASILTLGSLFLPETPNSIIQTTGDVHKTELMLRRVRGTNDVQDELTDLVEASSGSDTDSNAFLKLLQRKYRPELVMALVIPFFQQVTGINVVAFYAPVLYRTVGFGESGSLMSTLVTGIVGTSSTLLSMLVVDRIGRKTLFLIGGLQMLVSQVTIGVIVMVADVHDGVIKEGYGYAVVVLVCVYVAGFGWSWGPLGWLVPSEIFPLEIRSVAQSVTVAVSFVFTFAVAQSAPPMLCKFRAGIFFFYGGWLVVMTVAVQLFLPETKNVPIEKVVGLWEKHWFWRRMTSKRDIQETTILSH", "length": 514 }, "evidence": [ { "id": "Q9W3S8", "url": "https://omabrowser.org/oma/group/Q9W3S8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q8MKK4-1", "protein_name": "Trehalose transporter 1-like protein", "gene_name": "Tret1l", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKILMRADTHVSFSVPADGLKANFTFSQVLAALSVSLCSLVVGFVSAYTSPALVSMTDRTITSFEVTKDAGSWVGGIMPLAALAGGITGGPLIEYLGRRSTILATAVPFIVSSLLIACAVNVIMILCGRFLTGFCVGIASLSLPVYLGETLQPEVRGTLGLLPTALGNIGILVCYVAGSFMNWSMLAFLGAALPVPFLILMIIIPETPRWFVNRGQEERARKALKWLRGKEADVEPELKELMQSQADADRQATQNTCLELFKRNNLKPLSISLGLMFFQQFSGINAVIFYTVQIFKDAGSTIDSNLSTIIVGVVNFFATFMGIILIDRLGRKILLYVSDIAMIVTLSILGGFFYCKAHGPDVSHLGWLPLTCFVIYILGFSLGFGPIPWLMMGEILPAKIRGPAASVVTAFNWFCTFVVTKTFQDLTVAMGAHGAFWLFGAICIVGLFFVIIFVPETRGKSLEEIERKMMGRVPMSSVVNIKPFPFNM", "length": 488 }, "evidence": [ { "id": "RGD:620611", "url": "https://alliancegenome.org/gene/RGD:620611#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9JIF3-1", "protein_name": "Solute carrier family 2, facilitated glucose transporter member 8", "gene_name": "Slc2a8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSPEDPQETQPLLRPPEARTPRGRRVFLASFAAALGPLSFGFALGYSSPAIPSLRRTAPPALRLGDNAASWFGAVVTLGAAAGGILGGWLLDRAGRKLSLLLCTVPFVTGFAVITAARDVWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVTGILLAYVAGWVLEWRWLAVLGCVPPTLMLLLMCYMPETPRFLLTQHQYQEAMAALRFLWGSEEGWEEPPVGAEHQGFQLALLRRPGIYKPLIIGISLMVFQQLSGVNAIMFYANSIFEEAKFKDSSLASVTVGIIQVLFTAVAALIMDRAGRRLLLALSGVIMVFSMSAFGTYFKLTQSLPSNSSHVGLVPIAAEPVDVQVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTNWFMAFLVTKEFSSVMEMLRPYGAFWLTAAFCALSVLFTLTVVPETKGRTLEQVTAHFEGR", "length": 477 }, "evidence": [ { "id": "RGD:620611", "url": "https://alliancegenome.org/gene/RGD:620611#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JJZ1-1", "protein_name": "Solute carrier family 2, facilitated glucose transporter member 8", "gene_name": "Slc2a8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSPEDPQETQPLLRSPGARAPGGRRVFLATFAAALGPLSFGFALGYSSPAIPSLRRTAPPALRLGDTAASWFGAVVTLGAAAGGVLGGWLLDRAGRKLSLLLCTVPFVTGFAVITAARDVWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVTGILLAYVAGWVLEWRWLAVLGCVPPTLMLLLMCYMPETPRFLLTQHQYQEAMAALRFLWGSEEGWEEPPVGAEHQGFQLAMLRRPGVHKPLIIGICLMVFQQLSGVNAIMFYANTIFEEAKFKDSSLASVTVGIIQVLFTAVAALIMDRAGRKLLLALSGVIMVFSMSAFGTYFKLTQSGPSNSSHVGLLVPISAEPADVHLGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHIKGVATGVCVLTNWFMAFLVTKEFNSIMEILRPYGAFWLTAAFCILSVLFTLTFVPETKGRTLEQITAHFEGR", "length": 478 }, "evidence": [ { "id": "RGD:620611", "url": "https://alliancegenome.org/gene/RGD:620611#orthology", "database": "AGR" }, { "id": "FB:FBgn0029932", "url": "https://alliancegenome.org/gene/FB:FBgn0029932#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9NY64-1", "protein_name": "Solute carrier family 2, facilitated glucose transporter member 8", "gene_name": "SLC2A8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTPEDPEETQPLLGPPGGSAPRGRRVFLAAFAAALGPLSFGFALGYSSPAIPSLQRAAPPAPRLDDAAASWFGAVVTLGAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVITAAQDVWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLAYLAGWVLEWRWLAVLGCVPPSLMLLLMCFMPETPRFLLTQHRRQEAMAALRFLWGSEQGWEDPPIGAEQSFHLALLRQPGIYKPFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKFKDSSLASVVVGVIQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFGAYFKLTQGGPGNSSHVAISAPVSAQPVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTNWLMAFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTLFCVPETKGKTLEQITAHFEGR", "length": 477 }, "evidence": [ { "id": "RGD:620611", "url": "https://alliancegenome.org/gene/RGD:620611#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VU17-1", "protein_name": "Nebulosa, isoform B", "gene_name": "nebu", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSTASSSNSSGEEANKKSGSNNEESSHLLESAENGAKYGSRQPVKIVKASDNGRTSSTPHDQENLLGNMVHTSTSNNSQKWPQYVAALAAAGGAFAAGTVLGWTSPAETEIVDRGEGYDFPVDKDQFSWVGSAMTLGAACVCIPIGFLINMIGRKWTMLFLVLPFILGWTMLIWAVNVSMLYASRFILGIAGGAFCVTAPMYTGEIAQKEIRGTLGSFFQLMITIGILFVYAVGAGVKIFWLSIICGILPLIFGAIFFFMPESPTYLVSKDRSENAIKSIQWLRGKEYDYEPELAELRETDRETKANKVNVWAALNRPVTRKALAISMGLMFFQQVCGINAVIFYASRIFLEANTGIEAEWATILIGIMQVVATFVSTLVVDKLGRRILLLASGISMAISTTAIGVYFFLQKQDAAQVVSLGWLPVASLCLFIIMFSIGYGPVPWLMMGELFATDIKGFAGSLAGTSNWLLAFVVTKTFVNLNDGLGIGGTFWLFAGLTVVGVIFVYFAVPETKGKSLNEIQQELAGNRSTPQAIPAEK", "length": 539 }, "evidence": [ { "id": "RGD:620611", "url": "https://alliancegenome.org/gene/RGD:620611#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "sugar transmembrane transporter activity", "id": "GO:0051119", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051119", "evidence": [ { "database": 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"https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "Q9W3S8", "url": "https://www.uniprot.org/uniprotkb/Q9W3S8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 281, "end_pos": 283, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9W3S8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3S8" }, { "id": "PS50850", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50850" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Major facilitator superfamily (MFS) profile", "eco_id": "ECO_0000259", "start_pos": 48, "end_pos": 488, "start_aa": "Met", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 281, "end_pos": 283 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9W3T2-1", "uniprot_ac": "Q9W3T2", "uniprot_id": "Q9W3T2_DROME", "mass": { "chemical_mass": 24789.0, "monoisotopic_mass": 24789.0 }, "refseq": { "ac": "NP_001284975", "name": "uncharacterized protein, isoform B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001284975" }, "gene_names": [ { "name": "Dmel\\CG4593", "type": "recommended", "evidence": [ { "id": "Q9W3T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3T2" } ] }, { "name": "CG4593", "type": "synonym", "evidence": [ { "id": "NP_001284975", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001284975" }, { "id": "Q9W3T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3T2" } ] }, { "name": "Dmel\\CG4593", "type": "synonym", "evidence": [ { "id": "NP_001284975", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001284975" } ] }, { "name": "Dmel_CG4593", "type": "synonym", "evidence": [ { "id": "Q9W3T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3T2" } ] } ], "protein_names": [ { "name": "Coiled-coil domain-containing protein 25", "type": "recommended", "evidence": [ { "id": "Q9W3T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3T2/entry#names_and_taxonomy" } ] }, { "name": "CG4593-PB", "type": "synonym", "evidence": [ { "id": "NP_001284975", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001284975" } ] }, { "name": 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"database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0029929", "url": "https://bgee.org/?page=gene&gene_id=FBgn0029929", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0029929", "url": "https://flybase.org/reports/FBgn0029929", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "31649", "url": "https://www.ncbi.nlm.nih.gov/gene/31649", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008532", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008532", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039730", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039730", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG4593", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG4593", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YHDEKAV", "url": "https://omabrowser.org/oma/group/YHDEKAV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W3T2", "url": "https://www.orthodb.org/?gene=Q9W3T2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13049", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13049", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13049:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13049:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05670", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05670", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001284975", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001284975", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W3T2", "url": "https://www.uniprot.org/uniprotkb/Q9W3T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W3T2-1", "url": "https://www.uniprot.org/uniprotkb/Q9W3T2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVFYFKSNVVQPPAMLYMGRDKHENEELIRWGWPEDVWFHVHDLSSAHVYLRLRKGQTIDDIPTDVLVDAAQLCKANSIQGNKVNNLEVVYTMWENLKKTPDMEPGQVAYHNEKAVRRIRLEKRINEIVNRLNRTKTEEEHPDFRGLREARDAAERQDQKKIQRERREQEKEAAKQRELEAELRSYASLQKSENMRTNYDAGNESDDFM", "length": 209, "header": "tr|Q9W3T2-1|Q9W3T2_DROME Isoform 1 of Coiled-coil domain-containing protein 25 OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG4593 PE=1 SV=1 CANONICAL=Q9W3T2-1" }, "isoforms": [ { "isoform_ac": "Q9W3T2-1", "url": "https://www.uniprot.org/uniprotkb/Q9W3T2/entry#Q9W3T2-1", "sequence": { "sequence": "MVFYFKSNVVQPPAMLYMGRDKHENEELIRWGWPEDVWFHVHDLSSAHVYLRLRKGQTIDDIPTDVLVDAAQLCKANSIQGNKVNNLEVVYTMWENLKKTPDMEPGQVAYHNEKAVRRIRLEKRINEIVNRLNRTKTEEEHPDFRGLREARDAAERQDQKKIQRERREQEKEAAKQRELEAELRSYASLQKSENMRTNYDAGNESDDFM", "length": 209, "header": "tr|Q9W3T2-1|Q9W3T2_DROME Isoform 1 of Coiled-coil domain-containing protein 25 OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG4593 PE=1 SV=1 CANONICAL=Q9W3T2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W3T2", "url": "https://www.uniprot.org/uniprotkb/Q9W3T2" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W3T2", "url": "https://www.uniprot.org/uniprotkb/Q9W3T2" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3T2", "url": "https://www.uniprot.org/uniprotkb/Q9W3T2" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3T2", "url": "https://www.uniprot.org/uniprotkb/Q9W3T2" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W3T2", "url": "https://www.uniprot.org/uniprotkb/Q9W3T2" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W3T2", "url": "https://www.uniprot.org/uniprotkb/Q9W3T2" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W3T2", "url": "https://www.uniprot.org/uniprotkb/Q9W3T2" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3T2", "url": "https://www.uniprot.org/uniprotkb/Q9W3T2" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3T2", "url": "https://www.uniprot.org/uniprotkb/Q9W3T2" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"pathway": [ { "id": "dme:Dmel_CG4593", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG4593", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1VBD7-1", "protein_name": "Coiled-coil domain-containing protein 25", "gene_name": "CCDC25", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVFYFTSSSVNSSAYTIYMGKDKYENEDLIKYGWPEDIWFHVDKLSSAHVYLRLHKGEKIEDIPKEVLMDCAHLVKANSIQGCKMNNVNVVYTPWSNLKKTADMDVGQIGFHRQKDVKIVTVEKKVNEILNRLEKTKMERFPDLEAEKECRDREERNEKKAQIQEMKRREKEEMKKKREMDELRSYSSLMKVENMSSNQDGNDSDEFM", "length": 208 }, "evidence": [ { "id": "Q9W3T2", "url": "https://omabrowser.org/oma/group/Q9W3T2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2M417-1", "protein_name": "Coiled-coil domain-containing protein 25", "gene_name": "Ccdc25", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": 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"url": "https://www.ncbi.nlm.nih.gov/protein/NP_001284974" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W3T3", "url": "https://www.uniprot.org/uniprotkb/Q9W3T3" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG3032", "url": "https://www.uniprot.org/uniprotkb/Q9W3T3", "locus": { "chromosome": "X", "start_pos": 7012239, "end_pos": 7013881, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0029928", "url": "https://www.ensemblgenomes.org/id/FBgn0029928" } ] } } ], "crossref": [ { "id": "FB:FBgn0029928", "url": "https://alliancegenome.org/gene/FB:FBgn0029928", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0029928", "url": "https://bgee.org/?page=gene&gene_id=FBgn0029928", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0029928", "url": "https://flybase.org/reports/FBgn0029928", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "31648", "url": "https://www.ncbi.nlm.nih.gov/gene/31648", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012934", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012934", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050888", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050888", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG3032", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3032", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YHTMQQH", "url": "https://omabrowser.org/oma/group/YHTMQQH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W3T3", "url": "https://www.orthodb.org/?gene=Q9W3T3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24406", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24406", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07776", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07776", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13894", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13894", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001284974", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001284974", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W3T3", "url": "https://www.uniprot.org/uniprotkb/Q9W3T3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W3T3-1", "url": "https://www.uniprot.org/uniprotkb/Q9W3T3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPLNLTRESVRELCCTCLLQLEKEPLKTELQSDEIPISQELQQLLNINLSQDVENQDADQQWLPNELCLECRSAVQNFEKFRRKADECRKQLLEMLKKDPREPTFEVVYDGREEDQESLHGLEPPEPAPDPDPIDEPAIKSDKSPRKSFRGSRNTLKCSVCRRSFAHQITLAAHIRKVHEGSKRPFQCDQCEKAYSFMGGLYTHIREVHAPKERRHPCDQPGCERIYTSRIAMQKHKRLKHSPRDRDALKKFICEQCGASFNQSANLKYHLKTKHPTEDEVAAREGGAGERHFCDICQKEFHSRYTLKYHTLQQHEVQEELPHECQVCGRRMAKKFMLLQHMLMHSNDKLPCEHCGRRFARRFELEAHVRAVHLKLKPFPCHHCPESFASRKTLRHHEYIHTGEKPYICDTCGQAFRQQTCLKNHRKVHEK", "length": 431, "header": "tr|Q9W3T3-1|Q9W3T3_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG3032 PE=4 SV=1 CANONICAL=Q9W3T3-1" }, "isoforms": [ { "isoform_ac": "Q9W3T3-1", "url": "https://www.uniprot.org/uniprotkb/Q9W3T3/entry#Q9W3T3-1", "sequence": { "sequence": "MPLNLTRESVRELCCTCLLQLEKEPLKTELQSDEIPISQELQQLLNINLSQDVENQDADQQWLPNELCLECRSAVQNFEKFRRKADECRKQLLEMLKKDPREPTFEVVYDGREEDQESLHGLEPPEPAPDPDPIDEPAIKSDKSPRKSFRGSRNTLKCSVCRRSFAHQITLAAHIRKVHEGSKRPFQCDQCEKAYSFMGGLYTHIREVHAPKERRHPCDQPGCERIYTSRIAMQKHKRLKHSPRDRDALKKFICEQCGASFNQSANLKYHLKTKHPTEDEVAAREGGAGERHFCDICQKEFHSRYTLKYHTLQQHEVQEELPHECQVCGRRMAKKFMLLQHMLMHSNDKLPCEHCGRRFARRFELEAHVRAVHLKLKPFPCHHCPESFASRKTLRHHEYIHTGEKPYICDTCGQAFRQQTCLKNHRKVHEK", "length": 431, "header": "tr|Q9W3T3-1|Q9W3T3_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG3032 PE=4 SV=1 CANONICAL=Q9W3T3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W3T3", "url": "https://www.uniprot.org/uniprotkb/Q9W3T3" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W3T3", "url": "https://www.uniprot.org/uniprotkb/Q9W3T3" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3T3", "url": "https://www.uniprot.org/uniprotkb/Q9W3T3" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3T3", "url": "https://www.uniprot.org/uniprotkb/Q9W3T3" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W3T3", "url": "https://www.uniprot.org/uniprotkb/Q9W3T3" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W3T3", "url": "https://www.uniprot.org/uniprotkb/Q9W3T3" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W3T3", "url": "https://www.uniprot.org/uniprotkb/Q9W3T3" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3T3", "url": "https://www.uniprot.org/uniprotkb/Q9W3T3" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3T3", "url": "https://www.uniprot.org/uniprotkb/Q9W3T3" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W3T3", "url": "https://www.uniprot.org/uniprotkb/Q9W3T3" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W3T3", "url": "https://www.uniprot.org/uniprotkb/Q9W3T3" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], 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"MGNKQIKQQLETAQKTGILKISLQRLQEFPLQLRAYPNVLKTLDLSENRFERVPDELGKLTLLKHLNLSGNRLVELNEVVGELAKLEVLLLMDNMLTRLPKTLANCTHLKTVNLSNNQLKEFPSMLCGLKQLDVLDLSRNKITDVPADVGGLFVTELNLNQNQISSLAEEVADCPKLKTLRLEENCLQAAAFTPKILKDSKICNLAVDGNLFNSKQFTDLDGYDVYMERYTAVRKKMF", "length": 238, "header": "tr|Q9W3T9-1|Q9W3T9_DROME Isoform 1 of Leucine-rich repeat-containing protein 57 OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG3040 PE=1 SV=2 CANONICAL=Q9W3T9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W3T9", "url": "https://www.uniprot.org/uniprotkb/Q9W3T9" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W3T9", "url": "https://www.uniprot.org/uniprotkb/Q9W3T9" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3T9", "url": "https://www.uniprot.org/uniprotkb/Q9W3T9" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3T9", "url": "https://www.uniprot.org/uniprotkb/Q9W3T9" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W3T9", "url": "https://www.uniprot.org/uniprotkb/Q9W3T9" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W3T9", "url": "https://www.uniprot.org/uniprotkb/Q9W3T9" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W3T9", "url": "https://www.uniprot.org/uniprotkb/Q9W3T9" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3T9", "url": "https://www.uniprot.org/uniprotkb/Q9W3T9" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3T9", "url": "https://www.uniprot.org/uniprotkb/Q9W3T9" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"pathway": [ { "id": "dme:Dmel_CG3040", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3040", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1L1RZ25-1", "protein_name": "Leucine-rich repeat-containing protein 57", "gene_name": "LRRC57", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGNSALKAHLETAQKTGVFQLTGKGLTEFPEELQKLTSNLRTIDLSNNKIELLPPLIGKFSFLKSLVLNNNKLTVLPEELCRLKKLETLHLNGNHLRQLPAAFGQLSALKTLNLSGNQLRTVPTQLCGLRHLDVVDLSKNQIQNVPDSVGELQAIELNLNQNQISQISVQISHCPRLKVLRLEENCLELSMLPQSILSDSQISLLAVEGNLFEIKKLRELEGYDKYMERFTATKKKFA", "length": 238 }, "evidence": [ { "id": "Q9W3T9", "url": "https://omabrowser.org/oma/group/Q9W3T9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A9J7G775-1", "protein_name": "Leucine-rich repeat-containing protein 57", "gene_name": "Lrrc57", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": 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"https://omabrowser.org/oma/group/Q9W3T9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5FVI3-1", "protein_name": "Leucine-rich repeat-containing protein 57", "gene_name": "Lrrc57", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGNSALRAHVETAQKTGVFQLKDRGLTEFPSELQKLTSNLRTIDLSNNKIDSLPPLIIGKFTLLKSLSLNNNKLTVLPDELCNLKKLETLSLNNNHLRELPSSFGQLSALKTLSLSGNQLGALPPQLCSLRHLDVVDLSKNQIRSIPDTVGELQAIELNLNQNQISQISVRISCCPRLKVLRLEENCLELSMLPQSILSDSQICLLAVEGNLFEIKKLRELEGYDKYMERFTATKKKFA", "length": 239 }, "evidence": [ { "id": "HGNC:26719", "url": "https://alliancegenome.org/gene/HGNC:26719#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040718-372", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040718-372#orthology", "database": "AGR" }, { "id": "MGI:1913856", "url": "https://alliancegenome.org/gene/MGI:1913856#orthology", "database": "AGR" }, { "id": "RGD:1307128", "url": 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"MGNSALRAHVETAQKTGVFQLKDRGLTEFPADLQKLTSNLRTIDLSNNKIESLPPLLIGKFTLLKSLSLNNNKLTVLPDEICNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGALPPQLCSLRHLDVMDLSKNQIRSIPDSVGELQVIELNLNQNQISQISVKISCCPRLKILRLEENCLELSMLPQSILSDSQICLLAVEGNLFEIKKLRELEGYDKYMERFTATKKKFA", "length": 239 }, "evidence": [ { "id": "HGNC:26719", "url": "https://alliancegenome.org/gene/HGNC:26719#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040718-372", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040718-372#orthology", "database": "AGR" }, { "id": "MGI:1913856", "url": "https://alliancegenome.org/gene/MGI:1913856#orthology", "database": "AGR" }, { "id": "RGD:1307128", "url": "https://alliancegenome.org/gene/RGD:1307128#orthology", "database": "AGR" }, { "id": "FB:FBgn0029925", "url": "https://alliancegenome.org/gene/FB:FBgn0029925#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D1G5-1", "protein_name": "Leucine-rich repeat-containing protein 57", "gene_name": "Lrrc57", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGNSALRAHVETAQKTGVFQLKDRGLTEFPSELQKLTSNLRTIDLSNNKIDSLPPLIIGKFTLLKSLSLNNNKLTVLPDELCNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGALPPQLCCLRHLDVVDLSKNQIRSIPDTVGELQAIELNLNQNQISQLSVKISCCPRLKVLRLEENCLELSMLPQSILSDSQICLLAVEGNLFEIKKFRELEGYDKYMERFTATKKKFA", "length": 239 }, "evidence": [ { "id": "HGNC:26719", "url": "https://alliancegenome.org/gene/HGNC:26719#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040718-372", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040718-372#orthology", "database": "AGR" }, { "id": "MGI:1913856", "url": "https://alliancegenome.org/gene/MGI:1913856#orthology", "database": "AGR" }, { "id": "RGD:1307128", "url": "https://alliancegenome.org/gene/RGD:1307128#orthology", "database": "AGR" }, { "id": "FB:FBgn0029925", "url": "https://alliancegenome.org/gene/FB:FBgn0029925#orthology", "database": "AGR" }, { "id": "Q9W3T9", "url": "https://omabrowser.org/oma/group/Q9W3T9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 105, "end_pos": 107, "annotation": "n_glycosylation_sequon" }, { "start_pos": 113, "end_pos": 115, "annotation": "n_glycosylation_sequon" }, { "start_pos": 67, "end_pos": 69, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 105, "end_pos": 107 }, { "start_pos": 113, "end_pos": 115 }, { "start_pos": 67, "end_pos": 69 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { 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"Protein Classification" ] }, { "id": "PTHR46515:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46515:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12325", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12325", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12329", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12329", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q9W3V2", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q9W3V2", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-DME-6811440", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6811440", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_572360", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572360", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W3V2", "url": "https://www.uniprot.org/uniprotkb/Q9W3V2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W3V2-1", "url": "https://www.uniprot.org/uniprotkb/Q9W3V2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSWFEKAKTVLIEALDIQDDDSKAAEKDSPMAGAASDGGASPGNNATAETPGSAATPASDTPTFFDNPHANEMVTIPPTPTSVPGSAAYGKRQSATSDSVDLLSSPTSPISPCGGDVPSVAKRLSESSLELITATTASEVEMSPDTEPSLPDSIVIIASNDTSDNAEGDGEDDDDEGTQLKRHMEDHLNDSTKTMKALVLSDIQVAGNADSDSTQSFEDIQLQMSHKGKSPAPAKTGTVDQSYSSTSSDIEIISNPNGDSSTNSTTTRTSPQKFKELAGGKVCLKAKGHHREPSEISLLSEDSQSELDKLVQRISELNQVIEAREQRLLQSERQNAELLERNQELRARVEAAANSANSPDAADAVQRLSALEKKFQASIRERDALRIQMKSLRDELQNKIPRDELAECNEMIAALQSEGEKLSKEILQQSTIIKKLRAKEKTSDTLLKKNGEQISLLSSESERLKRSLAAKEEMERTQIEAVCRMTAEKKRVDEENAESRSRIEDLQSRLAALQASFDGLKGDLQKRTRLEQDSLRAEHQEYVQQVSDLREKLRLAEHSLARREQQMREENRQLMRRLEAAELRAESSTQELGATTTPLIRQIESLQRTLDQRSAAWNREEQQLLQKLDDSQVQLRSLQQLESVQGEKQELLRTRCGLLEEKLSSALMEAEAAKMALRQHDLEAANKENDHKKQLSLLQEEIQQQQERIASLEQLCQRQKEEEEQRKQPTLLTVKAVKASSELQPQLQMQLPKSQAPLRSSPPLSLVDDSGSNEEALGGMIDWQADDLDCASNSGRQQSGIIQGVHLSFLAANTTTFEHLQALLKQRDGELTHLQWEVSRLQAERSVLDAEISNLTIELETMKEKQQMYEVMEKGYEDLQHRYDALLQMYGEKVERTEELELDLTELKAAYKLQIDELLAAPPPNLQRPSKQT", "length": 933, "header": "tr|Q9W3V2-1|Q9W3V2_DROME Isoform 1 of TATA element modulatory factor OS=Drosophila melanogaster OX=7227 GN=Tmf PE=4 SV=1 CANONICAL=Q9W3V2-1" }, "isoforms": [ { "isoform_ac": "Q9W3V2-1", "url": "https://www.uniprot.org/uniprotkb/Q9W3V2/entry#Q9W3V2-1", "sequence": { "sequence": "MSWFEKAKTVLIEALDIQDDDSKAAEKDSPMAGAASDGGASPGNNATAETPGSAATPASDTPTFFDNPHANEMVTIPPTPTSVPGSAAYGKRQSATSDSVDLLSSPTSPISPCGGDVPSVAKRLSESSLELITATTASEVEMSPDTEPSLPDSIVIIASNDTSDNAEGDGEDDDDEGTQLKRHMEDHLNDSTKTMKALVLSDIQVAGNADSDSTQSFEDIQLQMSHKGKSPAPAKTGTVDQSYSSTSSDIEIISNPNGDSSTNSTTTRTSPQKFKELAGGKVCLKAKGHHREPSEISLLSEDSQSELDKLVQRISELNQVIEAREQRLLQSERQNAELLERNQELRARVEAAANSANSPDAADAVQRLSALEKKFQASIRERDALRIQMKSLRDELQNKIPRDELAECNEMIAALQSEGEKLSKEILQQSTIIKKLRAKEKTSDTLLKKNGEQISLLSSESERLKRSLAAKEEMERTQIEAVCRMTAEKKRVDEENAESRSRIEDLQSRLAALQASFDGLKGDLQKRTRLEQDSLRAEHQEYVQQVSDLREKLRLAEHSLARREQQMREENRQLMRRLEAAELRAESSTQELGATTTPLIRQIESLQRTLDQRSAAWNREEQQLLQKLDDSQVQLRSLQQLESVQGEKQELLRTRCGLLEEKLSSALMEAEAAKMALRQHDLEAANKENDHKKQLSLLQEEIQQQQERIASLEQLCQRQKEEEEQRKQPTLLTVKAVKASSELQPQLQMQLPKSQAPLRSSPPLSLVDDSGSNEEALGGMIDWQADDLDCASNSGRQQSGIIQGVHLSFLAANTTTFEHLQALLKQRDGELTHLQWEVSRLQAERSVLDAEISNLTIELETMKEKQQMYEVMEKGYEDLQHRYDALLQMYGEKVERTEELELDLTELKAAYKLQIDELLAAPPPNLQRPSKQT", "length": 933, "header": "tr|Q9W3V2-1|Q9W3V2_DROME Isoform 1 of TATA element modulatory factor OS=Drosophila melanogaster OX=7227 GN=Tmf PE=4 SV=1 CANONICAL=Q9W3V2-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 56, "start_aa": "Thr", "end_pos": 56, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr56", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 79, "start_aa": "Thr", "end_pos": 79, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr79", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W3V2", "url": "https://www.uniprot.org/uniprotkb/Q9W3V2" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W3V2", "url": "https://www.uniprot.org/uniprotkb/Q9W3V2" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3V2", "url": "https://www.uniprot.org/uniprotkb/Q9W3V2" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3V2", "url": "https://www.uniprot.org/uniprotkb/Q9W3V2" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W3V2", "url": "https://www.uniprot.org/uniprotkb/Q9W3V2" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W3V2", "url": "https://www.uniprot.org/uniprotkb/Q9W3V2" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W3V2", "url": "https://www.uniprot.org/uniprotkb/Q9W3V2" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3V2", "url": "https://www.uniprot.org/uniprotkb/Q9W3V2" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3V2", "url": "https://www.uniprot.org/uniprotkb/Q9W3V2" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W3V2", "url": "https://www.uniprot.org/uniprotkb/Q9W3V2" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W3V2", "url": "https://www.uniprot.org/uniprotkb/Q9W3V2" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG4557", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG4557", "resource": "KEGG Pathway" }, { "id": "R-DME-6811440", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6811440", "resource": "Reactome", "description": "Retrograde transport at the Trans-Golgi-Network" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JZ48-1", "protein_name": "TATA element modulatory factor 1", "gene_name": "Tmf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSWFNASQLSSFAKQALSQAQKSIDRVLDIQEEEPSAWAEAIPYGISPSVSGGWDTSTWGLNSSSEPQSSPTASQAITKPVRRTVVDESENFFSAFLSPSDVQTIQKSPVVSKPPAKSQRPEEEVKSSLQEPSSPGQSRTSETAESEATDSACVSGETPAVGTPSPVPEGKREETASEESEGKVPTVRAKASESVVKVNTAEDVSPTSTQSLTTETKDMALEPKEQKHEDRQSNTPSPPVSSFSSGTSTTSDIEVLDHESVISESSASSRQETSDAKSSLHLMQTSFQLLSASACPEYGRLDDFQKLSESCCSSDAFERIDSFSVQSLDSRSVSEINSDDELPGRGYALVPIVVSPSAPKTKVVESTEENVEEEEGNETLIAPSEEAELEESGRSATPVNCDQPDTLASPTPVNVGPSASGPAAEDGEAAENHPKAPQLEQEDVGKTVEFLNEKLEKRETQLLSLSKEKALLEEAYDNLKDEMFRVKEESSSISSLKDEFTQRIAEAERKAQLACKERDTAKKEMKTMKEELASRLNSSQTADLLKEKDEQIQGLMEEGEKLSKQQLHNSNMIKKLRAKDKDNESVIAKLKKKAKELEEELQHLRQVLDGKEEVEKQHRENIKKLNSVVERQEKDLGRLQVDMNELEEKSRSTQAALDSAYRELTDLHKANAAKDSEVQEAALRREMKAKEELSGALEKAQEEARQQQETLALQVGDLRLALQRAEQAAARKEDYLRHEISELQQRLQEAENRNQELSQSVSSTTRPLLRQIENLQATLGSQTSSWEMLEKNLSDRLGESQTLLAAAVERERAATEELLANKIQMSSVESQNALLRQENSRLQAQLESEKNKLRKLEDENSRYQVELENLKDEYVRTLEEARKEKTLLSSQLEMERMKVEQERKKTIFTQETLKEKEHKPFSVSSTPTMSRSSSLSGVDMAGLQTSFLSQDESHDHSFGPMSTSASGSNLYEAVRMGAGSSIIENLQSQLKLREGEISHLQLEISNLEKTRSIMSEELVKLTNQNDELEEKVKEIPKLRVQLRDLDQRYNTILQMYGEKAEEAEELRLDLEDACGNPIKPYTSGARLAVLCKKTR", "length": 1095 }, "evidence": [ { "id": "MGI:2684999", "url": "https://alliancegenome.org/gene/MGI:2684999#orthology", "database": "AGR" }, { "id": "HGNC:11870", "url": "https://alliancegenome.org/gene/HGNC:11870#orthology", "database": "AGR" }, { "id": "RGD:620551", "url": "https://alliancegenome.org/gene/RGD:620551#orthology", "database": "AGR" }, { "id": "FB:FBgn0029912", "url": "https://alliancegenome.org/gene/FB:FBgn0029912#orthology", "database": "AGR" }, { "id": "SGD:S000003895", "url": "https://alliancegenome.org/gene/SGD:S000003895#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B9EKI3-1", "protein_name": "TATA element modulatory factor", "gene_name": "Tmf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSWFNASQLSSFAKQALSQAQKSIDRVLDIQEEEPSAWAEAIPYGEPGISPPVSGGWDTSTWGLNSTSSEPQSPPTASQAITKPVRRTVVDESENFFSAFLSPSDAHTIQKSPVVSKPPSKSQRPEEEVKSSLQESSSPGQSRVSETAEVRDSVCVSGETSAVGTPSPVPEDKHEETAGEESEVKVPTVRLKASENVVNVNTTEDVSTTSTQSLTAETKDMALEPKEQKHEDRQSNTPSPPVSSFSSGTSTTSDIEVLDHESVISESSASSRQETSDAKSSLHLMQTSFQLLSASACPEYSRLDDFQKLNESCCSSDAFERIDSFSVQSLDSRSVSEINSDDELPGKGYALVPIIVSPSTPKTKVVESTEENAEEEEGNETLVAPSEEAELEESGRSATPVNCDQPDILASPTAGSGGHSASGPATEQCEAVENQPKAPPEKEDVCKTVEFLNEKLEKRETQLLSLSKEKALLEEAYDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEMKTIKEELATRLNSSQTADLLKEKDEQIQGLMEEGEKLSKQQLHNSNIIKKLRAKDKDNENVIAKLNRKAKELEEELQHLRQVLDGKEEVEKQHRENIKKLNSVVERQEKDLGRLQVDMDELEEKSRSTQAALDSAYRELTDLHKANAAKDSEVQEAALRREMKAKEELSGALEKAQEEARQQQEALVLQVGDLRLALQRAEQAAARKEDYLRHEISELQQRLQEAENRNQELSQSVSSTARPLLRQIENLQATLGSQTSSWETLEKSLSDRLGESQTLLAAAVERERAATEELLANKIQMSSVESQNTLLRQENSRLQAQLESEKNKLRKLEDENSRYQVELENLKDEYVRTLEESRKEKTLLSSQLEMERMKVEQERKKTIFTQEALKEKDHKLFSVCSTPTMSRSSSISGVDAAGLQASFLSQDESHDHSFGPMSTSASGSNLYEAVRMGAGSSIIENLQSQLKLREGEISHLQLEISNLEKTRSIMSEELVKLTNQNDELEEKVKEIPKLRVQLRDLDQRYNTILQMYGEKAEEAEELRLDLEDVKNMYKTQIDELLRQRLS", "length": 1091 }, "evidence": [ { "id": "MGI:2684999", "url": "https://alliancegenome.org/gene/MGI:2684999#orthology", "database": "AGR" }, { "id": "HGNC:11870", "url": "https://alliancegenome.org/gene/HGNC:11870#orthology", "database": "AGR" }, { "id": "RGD:620551", "url": "https://alliancegenome.org/gene/RGD:620551#orthology", "database": "AGR" }, { "id": "FB:FBgn0029912", "url": "https://alliancegenome.org/gene/FB:FBgn0029912#orthology", "database": "AGR" }, { "id": "SGD:S000003895", "url": "https://alliancegenome.org/gene/SGD:S000003895#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1REB9-1", "protein_name": "TATA element modulatory factor", "gene_name": "tmf1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSWFNASHLSSFAKQALTTAQKSIDRVLDIKEEEWGDTTGQNFPDPPGKPAPTGWGMNQWNSPTEEQTTSPPPSSEAITTPVTRTVVDESEDFFSAFLPPGDVQAVSNTKVVSVAPAKSNRRLREKADKDKELVDNDLQGQAELSKSSSQEITEIKPAGAELSEQNSSTVEEQMQPELGIPASGVAPEQAVEQESIEDQTESDGLVLTLDVPLTNVPSFSSEGESVDSFDPPLNVETKNPDKTLPVPPKEIILESKDAKSEDRQSDTPSPPVSAFSSGTSTTSDIEVLDHESVLSESSASSRQETAEAKAGLHLMQGSFQLLSASTCSDFPRLDEYPKLTESCGSSSDAFERIDSFSVQSLDSRSVSEVNSDDEIPGNRTLASITAGPLPAPAESVPQTKQEEEEGMIESMNDQSLDDNEMEESGRSATPVNCEQVDELQEVDQEPEPDLTMSSQKIDVHETVTPLSTEEKPGDSPFQISELQKIIEELSGRLEKRESQLLAVSKDKARLEEECDNLKDEVISLKEESSSVQSLKDEFTQRIADAERKAQLSCKERDIAKKEIKGLREELASRLNSNETLELIKEKEEQIRELLEEGEKLSKQQLQHSNIIKKLRVKERESDAQIAKQTKKLKEQEEELKLLQQVMDGKEEIEKQHRENIKKLNAVVERQEKELSKLQTSSEELQEKSRSLQAALDSSYKELAELHKANASKDSEAQELALSREVQAKEELSLALEKVQEDSRLQQEALANQVADLRVALQRAEQQQAKKEDYLREEISELQQRIQEAETRNQELSQSVTSATRPLLRQIENLQATLGAQTASWEKLEKNLSDRLADAQAQLAVSVEKERSATEELLAIRAQITSFESQASLLRQEKGRLQGQLDAERMRREKLEDDLSRERVELENLKGEYARVSEDSKKEKLLLTNQLEMEKMKVEQEKKKCYLAQEALKEKERKSHQSVTDAPASSTPSLSRSSSVSGADHAGLPSSFFSQQEDSLDHSFNTMTMSISGTNLYEAARLGGGSSVIESLQSQLKLREGEITQLQMEIASLERSRTVMSEELIRLTNENDEMESKVKEIPRLKVQLKDLEQRHNTILQMYGEKAEEAEELRLDLEDVKNMYKLQIDELLKNQKQ", "length": 1135 }, "evidence": [ { "id": "MGI:2684999", "url": "https://alliancegenome.org/gene/MGI:2684999#orthology", "database": "AGR" }, { "id": "HGNC:11870", "url": "https://alliancegenome.org/gene/HGNC:11870#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P47166-1", "protein_name": "Protein SGM1", "gene_name": "SGM1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSKKLSLEERLSLATKKGRKKNKRSTSNLSSPSPVVLSNNEQESARTSIDDAAAGVVSIDNAENIDDPAVRSESTVEGDTGKADSIAVDDVVHPDHNRTDCFDDTMVSLPTWLPKNYTEFTVEELVKEISPEYLRLNKQIDDLTNELNRKSQIETTDSSFFKLIKEKDDLIDQLRKEGAKLAETELRQSNQIKALRTKVKDLEYEVSELNDSSAQSVENYNELQSLYHNIQGQLAEATNKLKDADKQKESLETLEKNIKEKDDLITILQQSLDNMRTLLEKEKSEFQTEKKALQEATVDQVTTLETKLEQLRIELDSSTQNLDAKSNRDFVDDQQSYEEKQHASFQYNRLKEQLESSKANWDSIEYALNTKIVNLENRFESTMKEKNDIEEKYQTALRSSETLGKQLEKEKENHSKAVLEVKDLERRAETLKSSLQSISDDYNLLKKKYEIQRSQLEQKENELKPHQENSNEKIIDKIPVELTDSLNSMEGNIEDEWTLPQENSMLSLSMSKLGELESDPSLKPIYNESHETICSEESQHFDRKNVDFSIDDIPEEAAALQAIREGESMNSLNNTSIPYRRASVQLSNSNGHISAHLVNKLSTELKRLEGELSASKELYDNLLKEKTKANDEILRLLEENDKFNEVNKQKDDLLKRVEQMQSKLETSLQLLGEKTEQVEELENDVSDLKEMMHQQVQQMVEMQGKMR", "length": 707 }, "evidence": [ { "id": "MGI:2684999", "url": "https://alliancegenome.org/gene/MGI:2684999#orthology", "database": "AGR" }, { "id": "HGNC:11870", "url": "https://alliancegenome.org/gene/HGNC:11870#orthology", "database": "AGR" }, { "id": "RGD:620551", "url": "https://alliancegenome.org/gene/RGD:620551#orthology", "database": "AGR" }, { "id": "FB:FBgn0029912", "url": "https://alliancegenome.org/gene/FB:FBgn0029912#orthology", "database": "AGR" }, { "id": "SGD:S000003895", "url": "https://alliancegenome.org/gene/SGD:S000003895#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P82094-1", "protein_name": "TATA element modulatory factor", "gene_name": "TMF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSWFNASQLSSFAKQALSQAQKSIDRVLDIQEEEPSIWAETIPYGEPGISSPVSGGWDTSTWGLKSNTEPQSPPIASPKAITKPVRRTVVDESENFFSAFLSPTDVQTIQKSPVVSKPPAKSQRPEEEVKSSLHESLHIGQSRTPETTESQVKDSSLCVSGETLAAGTSSPKTEGKHEETVNKESDMKVPTVSLKVSESVIDVKTTMESISNTSTQSLTAETKDIALEPKEQKHEDRQSNTPSPPVSTFSSGTSTTSDIEVLDHESVISESSASSRQETTDSKSSLHLMQTSFQLLSASACPEYNRLDDFQKLTESCCSSDAFERIDSFSVQSLDSRSVSEINSDDELSGKGYALVPIIVNSSTPKSKTVESAEGKSEEVNETLVIPTEEAEMEESGRSATPVNCEQPDILVSSTPINEGQTVLDKVAEQCEPAESQPEALSEKEDVCKTVEFLNEKLEKREAQLLSLSKEKALLEEAFDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEIKNIKEELATRLNSSETADLLKEKDEQIRGLMEEGEKLSKQQLHNSNIIKKLRAKDKENENMVAKLNKKVKELEEELQHLKQVLDGKEEVEKQHRENIKKLNSMVERQEKDLGRLQVDMDELEEKNRSIQAALDSAYKELTDLHKANAAKDSEAQEAALSREMKAKEELSAALEKAQEEARQQQETLAIQVGDLRLALQRTEQAAARKEDYLRHEIGELQQRLQEAENRNQELSQSVSSTTRPLLRQIENLQATLGSQTSSWEKLEKNLSDRLGESQTLLAAAVERERAATEELLANKIQMSSMESQNSLLRQENSRFQAQLESEKNRLCKLEDENNRYQVELENLKDEYVRTLEETRKEKTLLNSQLEMERMKVEQERKKAIFTQETIKEKERKPFSVSSTPTMSRSSSISGVDMAGLQTSFLSQDESHDHSFGPMPISANGSNLYDAVRMGAGSSIIENLQSQLKLREGEITHLQLEIGNLEKTRSIMAEELVKLTNQNDELEEKVKEIPKLRTQLRDLDQRYNTILQMYGEKAEEAEELRLDLEDVKNMYKTQIDELLRQSLS", "length": 1093 }, "evidence": [ { "id": "MGI:2684999", "url": "https://alliancegenome.org/gene/MGI:2684999#orthology", "database": "AGR" }, { "id": "HGNC:11870", "url": "https://alliancegenome.org/gene/HGNC:11870#orthology", "database": "AGR" }, { "id": "RGD:620551", "url": "https://alliancegenome.org/gene/RGD:620551#orthology", "database": "AGR" }, { "id": "FB:FBgn0029912", "url": "https://alliancegenome.org/gene/FB:FBgn0029912#orthology", "database": "AGR" }, { "id": "SGD:S000003895", "url": "https://alliancegenome.org/gene/SGD:S000003895#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q556B3-1", "protein_name": "TMF1-like protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSKWGNFNFDISAVGKVIKNVEKSIDKAIGIPDQPEGTENNDNNTSFSSSPGGGTSFFGYSFSTPTKSTSNNTPITSTPTKLQSGQTLTPTLTPIQNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNKQTNNSSNNSSILNITPIKPKIEQQSIPTPKYSENTSEEIGLKNKEDNKGEDEDEDEDEEKPLYQIDANLDSKSENILKEEKVNKNHDNGNNQNENENQNESENENEIENDNNNNNNSMNISKSLQMDKSELNQEINEIDTNSLQINTDHNKDLLNIDSINNTNEINNKENDNNIEKEEIQEIKPINNENVVNNNNNNNNNNNNNNNNNNNNNNNIIDNIIDYNNNNNNIDNNNINSNNNNNNNNNNNNNNNNNNNNNNNNNNNNELIIKENNELKQTIKEMENKMNIVVMINNEQKRIVTDKEKVIEDLTGKMSKLAILNDQLLGDINKLNVDSKKEDLENLKEEFSRRLGQVEKKLSNVTKERDQLRSGTTLPESIQITVKEKDEKITQLITEGTNLSHRILALESSLKKSKQTTKENEDTITMLNERINNTEQLLLTRSERLKEFEEADKRYQDTINTMKEVSDSASKKLDKRDQEADKAIRQATDLQAALDKAWKDIQDLNKHHSIEIDRYNKQLQEERSRIKSEFQLIANNEKKEFLDKIEQLETFIQEHRSTINRNNEKQTWKEEELNKEIAHLQQRCRDAEIRNDQLSSSIPQATRPLLKQIESIQEQFNERQSTWETLEKQLNNQLREERLKAEHVVRNQQEILSELEELTLKFQLLESESKIDKKKLKSTITELQQLKSIQSDHLSKIQDLESSSSTLQSKIDQHLNTISILEERLTLSNKELKDLEDKRQKEKELYEKETSNFLKKQQQLLLQQQLQQQQQQENQNQINNNNNNNNNNNNNNGSSLSNSTDKINNGSISTPPQQQNKGLFSGLKKTPSNHDFLNHSVGNGLLPASLEYLQSSLSQKEGEAMSLQAQVQSLNHSRKKLEDELVKLTTDNEELLSECKELKLQRQEIKDIQQRYQTTLLMLGEKEEAVNELRLDIMDLKDLYKNQINELLLQIEVLKKK", "length": 1084 }, "evidence": [ { "id": "Q9W3V2", "url": "https://omabrowser.org/oma/group/Q9W3V2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q9W3V2", "url": "https://www.uniprot.org/uniprotkb/Q9W3V2" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q9W3V2", "url": "https://www.uniprot.org/uniprotkb/Q9W3V2" } ], "pmid": "" }, { "name": "trans-Golgi network membrane", "id": "GO:0032588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032588", "evidence": [ { "database": "UniProtKB", "id": "Q9W3V2", "url": "https://www.uniprot.org/uniprotkb/Q9W3V2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "Q9W3V2", "url": "https://www.uniprot.org/uniprotkb/Q9W3V2" } ], "pmid": "" }, { "name": "cargo receptor activity", "id": "GO:0038024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038024", "evidence": [ { "database": "UniProtKB", "id": "Q9W3V2", "url": "https://www.uniprot.org/uniprotkb/Q9W3V2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "vesicle tethering to Golgi", "id": "GO:0099041", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099041", "evidence": [ { "database": "UniProtKB", "id": "Q9W3V2", "url": "https://www.uniprot.org/uniprotkb/Q9W3V2" } ], "pmid": "" }, { "name": "intra-Golgi vesicle-mediated transport", "id": "GO:0006891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006891", "evidence": [ { "database": "UniProtKB", "id": "Q9W3V2", "url": "https://www.uniprot.org/uniprotkb/Q9W3V2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 160, "end_pos": 162, "annotation": "n_glycosylation_sequon" }, { "start_pos": 189, "end_pos": 191, "annotation": "n_glycosylation_sequon" }, { "start_pos": 263, "end_pos": 265, "annotation": "n_glycosylation_sequon" }, { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" }, { "start_pos": 813, "end_pos": 815, "annotation": "n_glycosylation_sequon" }, { "start_pos": 854, "end_pos": 856, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9W3V2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3V2" }, { "id": "PF12325", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12325" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TATA element modulatory factor 1 TATA binding", "eco_id": "ECO_0000259", "start_pos": 812, "end_pos": 918, "start_aa": "Ala", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 56, 79 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 160, "end_pos": 162 }, { "start_pos": 189, "end_pos": 191 }, { "start_pos": 263, "end_pos": 265 }, { "start_pos": 45, "end_pos": 47 }, { "start_pos": 813, "end_pos": 815 }, { "start_pos": 854, "end_pos": 856 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9W3V5-1", "uniprot_ac": "Q9W3V5", "uniprot_id": "Q9W3V5_DROME", "mass": { "chemical_mass": 41897.0, "monoisotopic_mass": 41897.0 }, "refseq": { "ac": "NP_572358", "name": "muscarinic acetylcholine Receptor, C-type", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572358" }, "gene_names": [ { "name": "mAChR-C", "type": "recommended", "evidence": [ { "id": "Q9W3V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3V5" } ] }, { "name": "CG12796", "type": "synonym", "evidence": [ { "id": "NP_572358", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572358" }, { "id": "Q9W3V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3V5" } ] }, { "name": "Dmel\\CG12796", "type": "synonym", "evidence": [ { "id": "NP_572358", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572358" }, { "id": "Q9W3V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3V5" } ] }, { "name": "Dmel_CG12796", "type": "synonym", "evidence": [ { "id": "Q9W3V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3V5" } ] }, { "name": "mAChR-C", "type": "synonym", "evidence": [ { "id": "NP_572358", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572358" } ] } ], "protein_names": [ { "name": "CG12796-PA", "type": "synonym", "evidence": [ { "id": "NP_572358", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572358" } ] }, { "name": "Muscarinic acetylcholine Receptor, C-type", "type": "synonym", "evidence": [ { "id": "Q9W3V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3V5/entry#names_and_taxonomy" } ] }, { "name": "mAChR-C-PA", "type": "synonym", "evidence": [ { "id": "NP_572358", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572358" } ] }, { "name": "muscarinic acetylcholine Receptor, C-type", "type": "synonym", "evidence": [ { "id": "NP_572358", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572358" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W3V5", "url": "https://www.uniprot.org/uniprotkb/Q9W3V5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "mAChR-C", "url": "https://www.uniprot.org/uniprotkb/Q9W3V5", "locus": { "chromosome": "X", "start_pos": 6831397, "end_pos": 6832684, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0029909", "url": "https://www.ensemblgenomes.org/id/FBgn0029909" } ] } } ], "crossref": [ { "id": "FB:FBgn0029909", "url": "https://alliancegenome.org/gene/FB:FBgn0029909", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0029909", "url": "https://bgee.org/?page=gene&gene_id=FBgn0029909", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00637", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00637", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0029909", "url": "https://flybase.org/reports/FBgn0029909", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "31626", "url": "https://www.ncbi.nlm.nih.gov/gene/31626", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG12796", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG12796", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VRTCRHL", "url": "https://omabrowser.org/oma/group/VRTCRHL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W3V5", "url": "https://www.orthodb.org/?gene=Q9W3V5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24247", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24247", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24247:SF202", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24247:SF202", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_572358", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572358", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W3V5", "url": "https://www.uniprot.org/uniprotkb/Q9W3V5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W3V5-1", "url": "https://www.uniprot.org/uniprotkb/Q9W3V5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFTSSSSPAWDYRSSPEALGVVPFLWQHQNATETPTEITLQATSFGAGHLLWLAINAFLFVLILGGNILTIVAVRTCRHLRSVISNLFILSLAVSDFCVGLALPYHLVFYMGSDIGAMRGPCLLRFFLLICACCVSMLTLISIAVDRYIAVVYALHYRRYMTRRVAYSIIIFNWCLGALVALLPVFWNRWPDAQACEFDEVLAPGYIAGVITPGFVIIWICMFLVYWRIMREASKQALRLRQSVVYNTDEATTMRNLLLHPDWKSVQIVVFIMGCFTLCWLPYFCVAIAQLFSICQSSSMIYKTTFSLAIANSALNPIIYSWKNSGFRRAFVQTLCCRTARQCEDQLPADSKHRMEATSSSQEIKPKATQ", "length": 371, "header": "tr|Q9W3V5-1|Q9W3V5_DROME Isoform 1 of Muscarinic acetylcholine Receptor, C-type OS=Drosophila melanogaster OX=7227 GN=mAChR-C PE=3 SV=1 CANONICAL=Q9W3V5-1" }, "isoforms": [ { "isoform_ac": "Q9W3V5-1", "url": "https://www.uniprot.org/uniprotkb/Q9W3V5/entry#Q9W3V5-1", "sequence": { "sequence": "MAFTSSSSPAWDYRSSPEALGVVPFLWQHQNATETPTEITLQATSFGAGHLLWLAINAFLFVLILGGNILTIVAVRTCRHLRSVISNLFILSLAVSDFCVGLALPYHLVFYMGSDIGAMRGPCLLRFFLLICACCVSMLTLISIAVDRYIAVVYALHYRRYMTRRVAYSIIIFNWCLGALVALLPVFWNRWPDAQACEFDEVLAPGYIAGVITPGFVIIWICMFLVYWRIMREASKQALRLRQSVVYNTDEATTMRNLLLHPDWKSVQIVVFIMGCFTLCWLPYFCVAIAQLFSICQSSSMIYKTTFSLAIANSALNPIIYSWKNSGFRRAFVQTLCCRTARQCEDQLPADSKHRMEATSSSQEIKPKATQ", "length": 371, "header": "tr|Q9W3V5-1|Q9W3V5_DROME Isoform 1 of Muscarinic acetylcholine Receptor, C-type OS=Drosophila melanogaster OX=7227 GN=mAChR-C PE=3 SV=1 CANONICAL=Q9W3V5-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 163, "start_aa": "Thr", "end_pos": 163, "end_aa": "Thr", "residue": "Thr", 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Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W3V5", "url": "https://www.uniprot.org/uniprotkb/Q9W3V5" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W3V5", "url": "https://www.uniprot.org/uniprotkb/Q9W3V5" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3V5", "url": "https://www.uniprot.org/uniprotkb/Q9W3V5" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3V5", "url": "https://www.uniprot.org/uniprotkb/Q9W3V5" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W3V5", "url": "https://www.uniprot.org/uniprotkb/Q9W3V5" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W3V5", "url": "https://www.uniprot.org/uniprotkb/Q9W3V5" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W3V5", "url": "https://www.uniprot.org/uniprotkb/Q9W3V5" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3V5", "url": "https://www.uniprot.org/uniprotkb/Q9W3V5" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3V5", "url": "https://www.uniprot.org/uniprotkb/Q9W3V5" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3V7", "url": "https://www.uniprot.org/uniprotkb/Q9W3V7" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3V7", "url": 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Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W3V7", "url": "https://www.uniprot.org/uniprotkb/Q9W3V7" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W3V7", "url": "https://www.uniprot.org/uniprotkb/Q9W3V7" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3V7", "url": "https://www.uniprot.org/uniprotkb/Q9W3V7" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3V7", "url": "https://www.uniprot.org/uniprotkb/Q9W3V7" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W3V7", "url": "https://www.uniprot.org/uniprotkb/Q9W3V7" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W3V7", "url": "https://www.uniprot.org/uniprotkb/Q9W3V7" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG4547", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG4547", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8N7UW40-1", "protein_name": "Uncharacterized protein zmp:0000000926", "gene_name": "zmp:0000000926", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNPSPDRSKECLPPKKRESRQGSTDQPAPEDDFKPPAPFRSRRPHQPTEGPREGGDLLPPVPLPLPWPVSYTPSIHPHTYLPLQLGERRGSWREALCGRGVDGGLEQSVPQHSRWLSSDIPHINMQPLLSVPTFKSVYSGDSREMWSCGLSRPDYSSSLFSPHVFPQPAVYPPDSLPDSRLRYQSRRHNGIDGQDCKSGFSRRVPSCNDYGNDSVSRLDAPHANGRRRQENTSRQTPEKRLPPQVSTSAHSSPWDRDPRGTPKASMPPSPDTKAGKAITSQDHFGGSASPAGAQIYYTLGSLCPSAQQNPQVFPQPRSPLSCSARSSQNQHNSHGVETDWSSPAGPCRPPLAVLMGPDPPPSAVLPHFAKGSLIELAGGHLKRVEELKTEDFLRSADTLPEFHLSSCTILLISPGPTYGFNHLQVLLTDRNTQELLTVLSEYPFFVRDRGWSSCSPQRSAQLYGLQCRQLSTGDVCLALTPTPTHKPNLAPSESRGPPGGSREPPSGTELQNTHRPRKRRWSAPELEPGAQTHTHSPLPQHSHTHH", "length": 546 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-130530-929", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-929#orthology", "database": "AGR" }, { "id": "FB:FBgn0029907", "url": "https://alliancegenome.org/gene/FB:FBgn0029907#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AA52Z3H5-1", "protein_name": "Ataxin-1a isoform X1", "gene_name": "atxn1a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKSNQERSNECLPPKKREIPASTLPSEEKPMVMAPANESQRGGNLAWLASLASGHDKGRLHTSTSAESDGPQYKPLSATAESTPSSSTHSTRALSAVTTIPAVYTSPLSHSPSAIQYTPLPHNIHFINPPYSAPYAGYISPLAPPLAATTTTQREIYASSSSSPASKIDQHHQLGRPQGLVTTDNTSSPHSTQYVQIAGSPLSISPRTVSSPHTHLPLHLHPHHTLPLSGPSQVLVPYTESLLPKREEMRTRELLNGELEKDRRFGPSSESSAGKQGSTAKGGSSAQQHQIHQQQSPRHFEARHVVLPAEYTQDSTAMRTSLVLVPNNHSSTSADSGGASDKLPPSTSHHEKGGICAGKPVSRSSSLSSSLSFALPPPPVDNLKGAVPAQSPHAVIQTTLNSTESLSLSLPSTNFYSTQQPIIGYFAGTGHQQPLSYHTTLPQHLVIPGTQPVIIPVSGTEATATSTAALPHAFVTSTAPKVETFESPAPYPHPATAMVQAQLHLPVVPAPAGLLTTPPPPSAPSMPPYFTKGSIIQLADGELKRVEDLKTEDFIQSAEISNELKIDSSTVERIDSSHTANFAIIQFAVGAQRSQVSVEVLVEYPFFVFGQGWSSCCPDRTTQLLELPCTKLSVGDVCISLTLKNLRNGSIKKSQGQVLDAPALGPPLKSPKALSSGARGGVRHTEQENGLGQCADQGSRGGQGNRENGELRFGERDNCKAPTLTESETSSKPTGRKRRWSAPEGRKVENPEGEPPLTFPKPSFIPQEVKISIEGRSNIGK", "length": 781 }, "evidence": [ { "id": "HGNC:10548", "url": "https://alliancegenome.org/gene/HGNC:10548#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-759", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-759#orthology", "database": "AGR" }, { "id": "RGD:3624", "url": "https://alliancegenome.org/gene/RGD:3624#orthology", "database": "AGR" }, { "id": "MGI:104783", "url": "https://alliancegenome.org/gene/MGI:104783#orthology", "database": "AGR" }, { "id": "FB:FBgn0029907", "url": "https://alliancegenome.org/gene/FB:FBgn0029907#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZBC4-1", "protein_name": "Ataxin 1 like", "gene_name": "Atxn1l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKPVHERSQECLPPKKRDLPVTSCSTNHTPSSDASEWSRGVVVAGQSQTGARVSLGGDGTEAITGLTVDQYGMLYKVAVPPATFSPTGLPSVVNMSPLPPTFNVASSLIQHPGIHYPPVHYAQLPSTSLQFIGSPYSLPYAVPPNFLPNPLLSPSANLATTHLPHFVPYASLLAEEAAPPPQAASPAQSFTKSSSATSPPGQLPHHSNTQPLDLAPGRMPIYYQTSRLPAGYTLHETSTAGASPILTPQEGQSALEAAAANGQRQRERSVRRESEPLDSTSSKGESQGLVPVVECMVDGQLFSGSQTPRVEVAAPTHRGTPDTDLEVQRVVGALASQDYRVVAAQRKDEPSPLNLSHHTLDHQGEGRGSARNPTEVVEKNQTRVFYPQSHQEPVKHRPLPKAVVVANGNLVPTGTDPSLLPVGSEILVASSLDMQARATFPDKEPTPPPVTSSHLPSHFMKGAIIQLATGELKRVEDLQTQDFVRSAEVSGGLKIDSSTVVDIQESQWPGFVMLHFVVGEQQSKVSIEVPPEHPFFVYGQGWSSCSPGRTAQLFSLPCHRLQVGDVCISISLQSLNSNSVSQASCAPPGQLGTPRERPERTILGPRDLCDSEGKNQTSGEGSRVGEPSQPEPSAQACWPAPSFQRYSMQGEEARAALLRPSFIPQEVKLSIEGRSNAGK", "length": 679 }, "evidence": [ { "id": "RGD:9319286", "url": "https://alliancegenome.org/gene/RGD:9319286#orthology", "database": "AGR" }, { "id": "HGNC:33279", "url": "https://alliancegenome.org/gene/HGNC:33279#orthology", "database": "AGR" }, { "id": "MGI:3694797", "url": "https://alliancegenome.org/gene/MGI:3694797#orthology", "database": "AGR" }, { "id": "FB:FBgn0029907", "url": "https://alliancegenome.org/gene/FB:FBgn0029907#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7F6Z5-1", "protein_name": "Ataxin-1", "gene_name": "atxn1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKSNQERCNECLPPKKREILALEEKQVLVSAAVSESQSGENLAWLASVATMASMAHIPNNAGPSHSNSSEPDSPPPSNKALTVVAEYPPTTTSAGFSFSSNSSTYRGVLSGPTVLTASPAVLSTSLPQTIGSVQYTQLPPNLQLIGPYTSYISSHIVPSTSSPTQPQRTPQEILATTAVISQASSLDSQSHVISSIPNVSHSQCIQVESAPLGLTVSSPSTQLPLQIHPHSAVLAPHALALTPSQVVLHYTDGFIAKQPDSHRREVLNGALGDVTVVKHNTTMAKGISSQPDVEQNHKQNHNLGIQTQAQVLLPADYTTNDRAGLQTSLMLVSSSHLAANSNSDIQSILGKDHSSLHLAERGGICLGKPMSRVSSLTSSDSQVSPASTISPHTLIQAPHNAPQQELSTSLYSATQLPIIGYITSASGGPQQAVTGYQSNLPQHVVISGNPSLLIPVSATNINPSTAEPEVTRCSVIPSLANASTALPQTFINTSPPAAVASVLPNGKDITGSDGGLVPCAVPSPTQIQLPVLSGSVVRSPVPATPPISTSPHSSPSSPTAGLPPFFMKGSIIQLADGELKRVEDLRTEDFVQSAEVSGELKIDSSTVERIEGSGTPNAVIIQFSVGENKAQVCVEVLVEYPFFVFGQGWSSCCPDRTTQLLALSCAKLSVGDVCISLTLKSLKNSIQKKDHFSDSVMKHSLLNATKNNGPLMERPTQVDDLKKGHKIPSEVENSIVEKLIETSNTKIVLSLSENGGSNPQTLVNLQNQAEKTYTSTAERPISRKRRWSAPEKADMQKSREDPQILPKFSFIPHQLKVSIEGRSSTGC", "length": 827 }, "evidence": [ { "id": "HGNC:10548", "url": "https://alliancegenome.org/gene/HGNC:10548#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061218-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061218-2#orthology", "database": "AGR" }, { "id": "RGD:3624", "url": "https://alliancegenome.org/gene/RGD:3624#orthology", "database": "AGR" }, { "id": "MGI:104783", "url": "https://alliancegenome.org/gene/MGI:104783#orthology", "database": "AGR" }, { "id": "FB:FBgn0029907", "url": "https://alliancegenome.org/gene/FB:FBgn0029907#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FB74-1", "protein_name": "Ataxin-1-like", "gene_name": "atxn1l", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKPVHERNQECLPPKKRDLPVNNNNNNTSINTNSNSSSSISGGAGGSGIGPGGAGGGGEDAPSSQSSGANAESQSSEWVRAQTGVHYGVESAEGLVGLPVDQYSMLYKVALPTGTYSPTSLHPVLTHAYTVPSPMLQHTSVPYPPTFPHSSLQFVNPPYPTAVPYAVPPGFVPSSLIPPQSGISQPHLVPYPSVIQEGVVSSQPQPQVSSHAYTKMLAPLVLSSEQAATQVPIGTVGMLPTGELSPRGVPVFYHPAVRGVQSHSSSLEQDREVNGGDRDHGGRESHQDAVYSARSVRLMQTTVLEPQQDKSLKSRRPEGRMSPGQSSTPDTDLEVQQVVGRLASPVHGSSRKDASHVPLNLSQSSQRSRETQGEIRTAYALNPAESRAHQQQIVQQGHAVILANGQPVLVPLDYHHHHQQQQQPQQHHYQPNDVASAAIVASPATYTKAMDAAACLPERAVAEPPPQQGQQVISAPAPGAFPQAPLLAPTGPSHFMKGAIIQLATGELKRVEDLQTQDFVRSAEMSGGLKIDSSMVVDIRASQQRPGLVALHFNVGEQQSKVTIDVPPEHPFFVYGQGWSSCSPERTAQLYGLTCHHLQVGDVCVSVTLQQQAASQQKPPQQVQARTPTKANSTSGATPQPMGPPAPQHTPRPQSHLKIHREREHNKEEPMQIGGSRHIDMPPRPNRTSAEHTHSQSNYYLHTEGHAPGVGAASQRRWSAPGFQRYSIKNEDGRLVSAATSGSSRPSFIPQEVKLSIEGRSNAGK", "length": 765 }, "evidence": [ { "id": "HGNC:33279", "url": "https://alliancegenome.org/gene/HGNC:33279#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P0C7T5-1", "protein_name": "Ataxin-1-like", "gene_name": "ATXN1L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKPVHERSQECLPPKKRDLPVTSEDMGRTTSCSTNHTPSSDASEWSRGVVVAGQSQAGARVSLGGDGAEAITGLTVDQYGMLYKVAVPPATFSPTGLPSVVNMSPLPPTFNVASSLIQHPGIHYPPLHYAQLPSTSLQFIGSPYSLPYAVPPNFLPSPLLSPSANLATSHLPHFVPYASLLAEGATPPPQAPSPAHSFNKAPSATSPSGQLPHHSSTQPLDLAPGRMPIYYQMSRLPAGYTLHETPPAGASPVLTPQESQSALEAAAANGGQRPRERNLVRRESEALDSPNSKGEGQGLVPVVECVVDGQLFSGSQTPRVEVAAPAHRGTPDTDLEVQRVVGALASQDYRVVAAQRKEEPSPLNLSHHTPDHQGEGRGSARNPAELAEKSQARGFYPQSHQEPVKHRPLPKAMVVANGNLVPTGTDSGLLPVGSEILVASSLDVQARATFPDKEPTPPPITSSHLPSHFMKGAIIQLATGELKRVEDLQTQDFVRSAEVSGGLKIDSSTVVDIQESQWPGFVMLHFVVGEQQSKVSIEVPPEHPFFVYGQGWSSCSPGRTTQLFSLPCHRLQVGDVCISISLQSLNSNSVSQASCAPPSQLGPPRERPERTVLGSRELCDSEGKSQPAGEGSRVVEPSQPESGAQACWPAPSFQRYSMQGEEARAALLRPSFIPQEVKLSIEGRSNAGK", "length": 689 }, "evidence": [ { "id": "RGD:9319286", "url": "https://alliancegenome.org/gene/RGD:9319286#orthology", "database": "AGR" }, { "id": "HGNC:33279", "url": "https://alliancegenome.org/gene/HGNC:33279#orthology", "database": "AGR" }, { "id": "MGI:3694797", "url": "https://alliancegenome.org/gene/MGI:3694797#orthology", "database": "AGR" }, { "id": "FB:FBgn0029907", "url": "https://alliancegenome.org/gene/FB:FBgn0029907#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0C7T6-1", "protein_name": "Ataxin-1-like", "gene_name": "Atxn1l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKPVHERSQECLPPKKRDLPVTSEDMGRTTSCSTNHTPSSDASEWSRGVVVAGQSQTGARVSLGGDGTEAITGLTVDQYGMLYKVAVPPATFSPTGLPSVVNMSPLPPTFNVASSLIQHPGIHYPPVHYAQLPSTSLQFIGSPYSLPYAVPPNFLPSPLLSPSANLATTHLPHFVPYASLLAEEATPPPQAASPAQSFNKSSSATSPPGQLPHHSNTQPLDLAPGRMPIYYQMSRLPAGYTLHETSTAGASPILTPQEGQSALEAAAANGQRQRERNVRRESEALDSASSKGESQGLVPVVECMADGQLFSGSQTPRVEVAAPAHRGTPDTDLEVQRVVGALASQDYRVVAAQRKDEPSPLNLSHHNLDHQGEGRGSARNPTELVEKSQARVFYPQSHQEPVKHRPLPKAMVVANGNLVPTGTDPSLLPVGSEILVASSLDLQARATFPDKEPTPPPVTSSHLPSHFMKGAIIQLATGELKRVEDLQTQDFVRSAEVSGGLKIDSSTVVDIQESQWPGFVMLHFVVGEQQSKVSIEVPPEHPFFVYGQGWSSCSPGRTAQLFSLPCHRLQVGDVCISISLQSLNSNSVSQASCAPPGQLGTPRERPERTVLGPRDLCDSEGKNQPSGEGSRVGEPSQPEPGAQACWPAPSFQRFSMQGEEARAAMLRPSFIPQEVKLSIEGRSNAGK", "length": 687 }, "evidence": [ { "id": "RGD:9319286", "url": "https://alliancegenome.org/gene/RGD:9319286#orthology", "database": "AGR" }, { "id": "HGNC:33279", "url": "https://alliancegenome.org/gene/HGNC:33279#orthology", "database": "AGR" }, { "id": "MGI:3694797", "url": "https://alliancegenome.org/gene/MGI:3694797#orthology", "database": "AGR" }, { "id": "FB:FBgn0029907", "url": "https://alliancegenome.org/gene/FB:FBgn0029907#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P54253-1", "protein_name": "Ataxin-1", "gene_name": "ATXN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKSNQERSNECLPPKKREIPATSRSSEEKAPTLPSDNHRVEGTAWLPGNPGGRGHGGGRHGPAGTSVELGLQQGIGLHKALSTGLDYSPPSAPRSVPVATTLPAAYATPQPGTPVSPVQYAHLPHTFQFIGSSQYSGTYASFIPSQLIPPTANPVTSAVASAAGATTPSQRSQLEAYSTLLANMGSLSQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLITPGSPPPAQQNQYVHISSSPQNTGRTASPPAIPVHLHPHQTMIPHTLTLGPPSQVVMQYADSGSHFVPREATKKAESSRLQQAIQAKEVLNGEMEKSRRYGAPSSADLGLGKAGGKSVPHPYESRHVVVHPSPSDYSSRDPSGVRASVMVLPNSNTPAADLEVQQATHREASPSTLNDKSGLHLGKPGHRSYALSPHTVIQTTHSASEPLPVGLPATAFYAGTQPPVIGYLSGQQQAITYAGSLPQHLVIPGTQPLLIPVGSTDMEASGAAPAIVTSSPQFAAVPHTFVTTALPKSENFNPEALVTQAAYPAMVQAQIHLPVVQSVASPAAAPPTLPPYFMKGSIIQLANGELKKVEDLKTEDFIQSAEISNDLKIDSSTVERIEDSHSPGVAVIQFAVGEHRAQVSVEVLVEYPFFVFGQGWSSCCPERTSQLFDLPCSKLSVGDVCISLTLKNLKNGSVKKGQPVDPASVLLKHSKADGLAGSRHRYAEQENGINQGSAQMLSENGELKFPEKMGLPAAPFLTKIEPSKPAATRKRRWSAPESRKLEKSEDEPPLTLPKPSLIPQEVKICIEGRSNVGK", "length": 815 }, "evidence": [ { "id": "HGNC:10548", "url": "https://alliancegenome.org/gene/HGNC:10548#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-759", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-759#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061218-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061218-2#orthology", "database": "AGR" }, { "id": "RGD:3624", "url": "https://alliancegenome.org/gene/RGD:3624#orthology", "database": "AGR" }, { "id": "MGI:104783", "url": "https://alliancegenome.org/gene/MGI:104783#orthology", "database": "AGR" }, { "id": "FB:FBgn0029907", "url": "https://alliancegenome.org/gene/FB:FBgn0029907#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P54254-1", "protein_name": "Ataxin-1", "gene_name": "Atxn1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKSNQERSNECLPPKKREIPATSRPSEEKATALPSDNHCVEGVAWLPSTPGIRGHGGGRHGSAGTSGEHGLQGMGLHKALSAGLDYSPPSAPRSVPTANTLPTVYPPPQSGTPVSPVQYAHLSHTFQFIGSSQYSGPYAGFIPSQLISPSGNPVTSAVASAAGATTPSQRSQLEAYSTLLANMGSLSQAPGHKVEPPPQQHLSRAAGLVNPGSPPPPTQQNQYIHISSSPQSSGRATSPPPIPVHLHPHQTMIPHTLTLGPSSQVVVQYSDAGGHFVPRESTKKAESSRLQQAMQAKEVLNGEMEKSRRYGASSSVELSLGKASSKSVPHPYESRHVVVHPSPADYSSRDTSGVRGSVMVLPNSSTPSADLEAQQTTHREASPSTLNDKSGLHLGKPGHRSYALSPHTVIQTTHSASEPLPVGLPATAFYAGTQPPVIGYLSGQQQAITYAGGLPQHLVIPGNQPLLIPVGSPDMDTPGAASAIVTSSPQFAAVPHTFVTTALPKSENFNPEALVTQAAYPAMVQAQIHLPVVQSVASPTTASPTLPPYFMKGSIIQLANGELKKVEDLKTEDFIQSAEISNDLKIDSSTVERIEESHSPGVAVIQFAVGEHRAQVSVEVLVEYPFFVFGQGWSSCCPERTSQLFDLPCSKLSVGDVCISLTLKNLKNGSVKKGQPVDPASVLLKQAKTDSLAGSRHRYAEQENGINQGSAQVLSENGELKFPEKIGLPAAPFLSKIEPSKPTATRKRRWSAPETRKLEKSEDEPPLTLPKPSLIPQEVKICIEGRSNVGK", "length": 791 }, "evidence": [ { "id": "HGNC:10548", "url": "https://alliancegenome.org/gene/HGNC:10548#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-759", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-759#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061218-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061218-2#orthology", "database": "AGR" }, { "id": "RGD:3624", "url": "https://alliancegenome.org/gene/RGD:3624#orthology", "database": "AGR" }, { "id": "MGI:104783", "url": "https://alliancegenome.org/gene/MGI:104783#orthology", "database": "AGR" }, { "id": "FB:FBgn0029907", "url": "https://alliancegenome.org/gene/FB:FBgn0029907#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q63540-1", "protein_name": "Ataxin-1", "gene_name": "Atxn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKSNQERSNECLPPKKREIPATSRPSEEKATALPSDNHCVEGVAWLPSTPGSRGHGGGRHGPAGTSGEHGLQGMGLHKALSAGLDYSPPSAPRSVPTANTLPTVYPPPQSGTPVSPVQYAHLSHTFQFIGSSQYSGPYAGFIPSQLISPPGNPVTSAVASAAGATTPSQRSQLEAYSTLLANMGSLSQAPGHKVEPPPQQHLGRAAGLVNPGSPPPTQQNQYIHISSSPQSSGRATSPPIPVHLHPHQTMIPHTLTLGPSSQVVVQYSDAGGHFVPRESTKKAESSRLQQAMQAKEVLNGEMEKSRRYGASSSVELSLGKTSSKSVPHPYESRHVVVHPSPADYSSRDTSGVRGSVMVLPNSSTPSADLETQQATHREASPSTLNDKSGLHLGKPGHRSYALSPHTVIQTTHSASEPLPVGLPATAFYAGAQPPVIGYLSSQQQAITYAGGLPQHLVIPGTQPLLIPVGSPDMDTPGAASAIVTSSPQFAAVPHTFVTTALPKSENFNPEALVTQAAYPAMVQAQIHLPVVQSVASPAAASPTLPPYFMKGSIIQLANGELKKVEDLKTEDFIQSAEISNDLKIDSSTVERIEDSHSPGVAVIQFAVGEHRAQVSVEVLVEYPFFVFGQGWSSCCPERTSQLFDLPCSKLSVGDVCISLTLKNLKNGSVKKGQPVDPASALLKHAKTDSLAGSRHRYAEQENGINQGSAQVLSENGELKFPEKIGLPAAPFLTKIEPSKPTATRKRRWSAPETRKLEKSEDEPPLTLPKPSLIPQEVKICIEGRSNVGK", "length": 789 }, "evidence": [ { "id": "HGNC:10548", "url": "https://alliancegenome.org/gene/HGNC:10548#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-759", "url": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3W4" } ] }, { "name": "Dmel\\CG14437", "type": "synonym", "evidence": [ { "id": "NP_651967", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_651967" }, { "id": "Q9W3W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3W4" } ] }, { "name": "Dmel_CG14437", "type": "synonym", "evidence": [ { "id": "Q9W3W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3W4" } ] } ], "protein_names": [ { "name": "5-demethoxyubiquinone hydroxylase, mitochondrial", "type": "recommended", "evidence": [ { "id": "Q9W3W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3W4/entry#names_and_taxonomy" } ] }, { "name": "1.14.99.60", "type": "synonym", "evidence": [ { "id": "Q9W3W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3W4/entry#names_and_taxonomy" } ] }, { "name": "CG14437-PA", "type": "synonym", "evidence": [ { "id": 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}, { "id": "Q9W3W4-1", "url": "https://www.uniprot.org/uniprotkb/Q9W3W4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNGMLRRGLSRPEPRLLSKRYLSSATGGGSAGTTEGGSSETTPLRPRPNALTDEIIRVDHAGELGADRIYAGQMAILGNGPLGKTIGHMWEQEKEHRKQFEQLIQQHRVRPTIMTPIWNVAGFVLGAGTALMGEKAAMACTVAVETVIVEHYNDQLRQIMEAPNPDKELLATITKFRDEEQEHHDTGIDHGAEQAPFYQAMTEVIKFGCKTAIAISKKI", "length": 219, "header": "tr|Q9W3W4-1|Q9W3W4_DROME Isoform 1 of 5-demethoxyubiquinone hydroxylase, mitochondrial OS=Drosophila melanogaster OX=7227 GN=Coq7 PE=3 SV=2 CANONICAL=Q9W3W4-1" }, "isoforms": [ { "isoform_ac": "Q9W3W4-1", "url": "https://www.uniprot.org/uniprotkb/Q9W3W4/entry#Q9W3W4-1", "sequence": { "sequence": "MNGMLRRGLSRPEPRLLSKRYLSSATGGGSAGTTEGGSSETTPLRPRPNALTDEIIRVDHAGELGADRIYAGQMAILGNGPLGKTIGHMWEQEKEHRKQFEQLIQQHRVRPTIMTPIWNVAGFVLGAGTALMGEKAAMACTVAVETVIVEHYNDQLRQIMEAPNPDKELLATITKFRDEEQEHHDTGIDHGAEQAPFYQAMTEVIKFGCKTAIAISKKI", "length": 219, "header": "tr|Q9W3W4-1|Q9W3W4_DROME Isoform 1 of 5-demethoxyubiquinone hydroxylase, mitochondrial OS=Drosophila melanogaster OX=7227 GN=Coq7 PE=3 SV=2 CANONICAL=Q9W3W4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W3W4", "url": "https://www.uniprot.org/uniprotkb/Q9W3W4" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W3W4", "url": "https://www.uniprot.org/uniprotkb/Q9W3W4" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3W4", "url": "https://www.uniprot.org/uniprotkb/Q9W3W4" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3W4", "url": "https://www.uniprot.org/uniprotkb/Q9W3W4" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W3W4", "url": "https://www.uniprot.org/uniprotkb/Q9W3W4" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W3W4", "url": "https://www.uniprot.org/uniprotkb/Q9W3W4" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W3W4", "url": "https://www.uniprot.org/uniprotkb/Q9W3W4" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3W4", "url": "https://www.uniprot.org/uniprotkb/Q9W3W4" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3W4", "url": "https://www.uniprot.org/uniprotkb/Q9W3W4" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W3W4", "url": "https://www.uniprot.org/uniprotkb/Q9W3W4" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W3W4", "url": "https://www.uniprot.org/uniprotkb/Q9W3W4" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG14437", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG14437", "resource": "KEGG Pathway" }, { "id": "R-DME-2142789", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-2142789", "resource": "Reactome", "description": "Ubiquinol biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZGW7-1", "protein_name": "5-demethoxyubiquinone hydroxylase, mitochondrial", "gene_name": "COQ7", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAAGALAPALRCSLGRHRALSRAAGRRGRWPFLAEGASLRPCSTRAALDGINKAVVDRIIRVDHAGEYGANRIYAGQMAVLGRSAAGPLIQQMWNQEKDHLRKFNELMIAYRVRPTVLLPFWNVAGFILGAGSSLLGKKGAMACTVAVEESISDHYNNQIRTLMEEDPEKYKELMQIIKQCRDDELEHHDIGLEHDAERFFILRSPWMSFVSVTVMITNLLQCLLCSASVIMRL", "length": 235 }, "evidence": [ { "id": "Q9W3W4", "url": "https://omabrowser.org/oma/group/Q9W3W4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P41735-1", "protein_name": "5-demethoxyubiquinone hydroxylase, mitochondrial", "gene_name": "CAT5", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLSRVSVFKPASRGFSVLSSLKITEHTSAKHTEKPEHAPKCQNLSDAQAAFLDRVIRVDQAGELGADYIYAGQYFVLAHRYPHLKPVLKHIWDQEIHHHNTFNNLQLKRRVRPSLLTPLWKAGAFAMGAGTALISPEAAMACTEAVETVIGGHYNGQLRNLANQFNLERTDGTKGPSEEIKSLTSTIQQFRDDELEHLDTAIKHDSYMAVPYTVITEGIKTICRVAIWSAERI", "length": 233 }, "evidence": [ { "id": "RGD:2381", "url": "https://alliancegenome.org/gene/RGD:2381#orthology", "database": "AGR" }, { "id": "MGI:107207", "url": "https://alliancegenome.org/gene/MGI:107207#orthology", "database": "AGR" }, { "id": "HGNC:2244", "url": "https://alliancegenome.org/gene/HGNC:2244#orthology", "database": "AGR" }, { "id": "FB:FBgn0029502", "url": "https://alliancegenome.org/gene/FB:FBgn0029502#orthology", "database": "AGR" }, { "id": "SGD:S000005651", "url": "https://alliancegenome.org/gene/SGD:S000005651#orthology", "database": "AGR" }, { "id": "Q9W3W4", "url": "https://omabrowser.org/oma/group/Q9W3W4/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P97478-1", "protein_name": "NADPH-dependent 3-demethoxyubiquinone 3-hydroxylase, mitochondrial", "gene_name": "Coq7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAAGAIAAASVGRLRTGVRRPFSEYGRGLIIRCHSSGMTLDNINRAAVDRIIRVDHAGEYGANRIYAGQMAVLGRTSVGPVIQKMWDQEKNHLKKFNELMIAFRVRPTVLMPLWNVAGFALGAGTALLGKEGAMACTVAVEESIANHYNNQIRMLMEEDPEKYEELLQVIKQFRDEELEHHDTGLDHDAELAPAYALLKRIIQAGCSAAIYLSERF", "length": 217 }, "evidence": [ { "id": "RGD:2381", "url": "https://alliancegenome.org/gene/RGD:2381#orthology", "database": "AGR" }, { "id": "MGI:107207", "url": "https://alliancegenome.org/gene/MGI:107207#orthology", "database": "AGR" }, { "id": "HGNC:2244", "url": "https://alliancegenome.org/gene/HGNC:2244#orthology", "database": "AGR" }, { "id": "FB:FBgn0029502", "url": "https://alliancegenome.org/gene/FB:FBgn0029502#orthology", "database": "AGR" }, { "id": "SGD:S000005651", "url": "https://alliancegenome.org/gene/SGD:S000005651#orthology", "database": "AGR" }, { "id": "Q9W3W4", "url": "https://omabrowser.org/oma/group/Q9W3W4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q54VB3-1", "protein_name": "NADPH-dependent 3-demethoxyubiquinone 3-hydroxylase, mitochondrial", "gene_name": "coq7", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNSLIKSTKFLKKTNIIRSYCTKTNNNNNTNITKNVLSEIEKEKLKRQIIERIIRVDHAGEFGAARIYEGQLAVLANTKEGPLIREMADQEKEHQAKFNQLIYEKRVRPTILSPIWNVAGFGLGYVSALMGKEAAMAVTVAVETVISDHYNDQLRQLNDAGIDDKELKETIKKFRDDELEHMHIGIEHDAELAPLYKPFSELVKVGTKTAIWLSTRV", "length": 217 }, "evidence": [ { "id": "Q9W3W4", "url": "https://omabrowser.org/oma/group/Q9W3W4/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q63619-1", "protein_name": "NADPH-dependent 3-demethoxyubiquinone 3-hydroxylase, mitochondrial", "gene_name": "Coq7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGAGAIAAASVGCLRTGVPRPFSAYGRGLIIRCHSTGMTLDNINRAAVDQIIRVDHAGEYGANRIYAGQMAVLGRTSVGPVIQKMWDQEKNHLKKFNELMVAFRVRPTVLMPLWNVAGFALGAGTALLGKEGAMACTVAVEESIAHHYNNQIRMLMEEDAEKYEELLQVIKQFRDEELEHHDTGLEHDAELAPAYTLLKRLIQAGCSAAIYLSERF", "length": 217 }, "evidence": [ { "id": "RGD:2381", "url": "https://alliancegenome.org/gene/RGD:2381#orthology", "database": "AGR" }, { "id": "MGI:107207", "url": "https://alliancegenome.org/gene/MGI:107207#orthology", "database": "AGR" }, { "id": "HGNC:2244", "url": "https://alliancegenome.org/gene/HGNC:2244#orthology", "database": "AGR" }, { "id": "FB:FBgn0029502", "url": "https://alliancegenome.org/gene/FB:FBgn0029502#orthology", "database": "AGR" }, { "id": "SGD:S000005651", "url": "https://alliancegenome.org/gene/SGD:S000005651#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q99807-1", "protein_name": "NADPH-dependent 3-demethoxyubiquinone 3-hydroxylase, mitochondrial", "gene_name": "COQ7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSCAGAAAAPRLWRLRPGARRSLSAYGRRTSVRFRSSGMTLDNISRAAVDRIIRVDHAGEYGANRIYAGQMAVLGRTSVGPVIQKMWDQEKDHLKKFNELMVTFRVRPTVLMPLWNVLGFALGAGTALLGKEGAMACTVAVEESIAHHYNNQIRTLMEEDPEKYEELLQLIKKFRDEELEHHDIGLDHDAELAPAYAVLKSIIQAGCRVAIYLSERL", "length": 217 }, "evidence": [ { "id": "RGD:2381", "url": "https://alliancegenome.org/gene/RGD:2381#orthology", "database": "AGR" }, { "id": "MGI:107207", "url": "https://alliancegenome.org/gene/MGI:107207#orthology", "database": "AGR" }, { "id": "HGNC:2244", "url": "https://alliancegenome.org/gene/HGNC:2244#orthology", "database": "AGR" }, { "id": "FB:FBgn0029502", "url": "https://alliancegenome.org/gene/FB:FBgn0029502#orthology", "database": "AGR" }, { "id": "SGD:S000005651", "url": "https://alliancegenome.org/gene/SGD:S000005651#orthology", "database": "AGR" }, { "id": "Q9W3W4", "url": "https://omabrowser.org/oma/group/Q9W3W4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extrinsic component of mitochondrial inner membrane", "id": "GO:0031314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031314", "evidence": [ { "database": "UniProtKB", "id": "Q9W3W4", "url": "https://www.uniprot.org/uniprotkb/Q9W3W4" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9W3W4", "url": "https://www.uniprot.org/uniprotkb/Q9W3W4" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q9W3W4", "url": "https://www.uniprot.org/uniprotkb/Q9W3W4" } ], "pmid": "" }, { "name": "ubiquinone biosynthesis complex", "id": "GO:0110142", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110142", "evidence": [ { "database": "UniProtKB", "id": "Q9W3W4", "url": "https://www.uniprot.org/uniprotkb/Q9W3W4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9W3W4", "url": "https://www.uniprot.org/uniprotkb/Q9W3W4" } ], "pmid": "" }, { "name": "3-demethoxyubiquinol 3-hydroxylase activity", "id": "GO:0008682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008682", "evidence": [ { "database": "UniProtKB", "id": "Q9W3W4", "url": "https://www.uniprot.org/uniprotkb/Q9W3W4" } ], "pmid": "" }, { "name": "3-demethoxyubiquinone 3-hydroxylase (NADH) activity", "id": "GO:0160224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160224", "evidence": [ { "database": "UniProtKB", "id": "Q9W3W4", "url": "https://www.uniprot.org/uniprotkb/Q9W3W4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of reactive oxygen species metabolic process", "id": "GO:2000377", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000377", "evidence": [ { "database": "UniProtKB", "id": "Q9W3W4", "url": "https://www.uniprot.org/uniprotkb/Q9W3W4" } ], "pmid": "" }, { "name": "ubiquinone biosynthetic process", "id": "GO:0006744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006744", "evidence": [ { "database": "UniProtKB", "id": "Q9W3W4", "url": "https://www.uniprot.org/uniprotkb/Q9W3W4" } ], "pmid": "" }, { "name": "determination of adult lifespan", "id": "GO:0008340", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008340", "evidence": [ { "database": "UniProtKB", "id": "Q9W3W4", "url": "https://www.uniprot.org/uniprotkb/Q9W3W4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "50908", "name": "", "equation": "a 5-methoxy-2-methyl-3-(all-trans-polyprenyl)benzene-1,4-diol + AH2 + O2 = a 3-demethylubiquinol + A + H2O", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9W3W4-1" ], "evidence": [ { "id": "50908", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/50908" } ] }, { "id": "R-DME-2162186", "name": "COQ3 methylates DeMQ10H2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [ "R-ALL-2162265", "R-ALL-2162212" ], "output_participant_list": [], "enzyme_list": [ "Q9VVG6-1", "Q9VMQ5-1", "Q9VYF8-1", "Q9VIF3-1", "Q9W3W4-1" ], "evidence": [ { "id": "R-DME-2162186", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-2162186" } ] }, { "id": "R-DME-2162187", "name": "COQ6 hydroxylates DHB", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial inner membrane, mitochondrial matrix", "input_participant_list": [ "R-ALL-2395504", "R-ALL-2162207" ], "output_participant_list": [ "R-ALL-2395501" ], "enzyme_list": [ "Q9VVG6-1", "Q9VMQ5-1", "Q9VYF8-1", "Q9VIF3-1", "Q9W3W4-1" ], "evidence": [ { "id": "R-DME-2162187", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-2162187" } ] }, { "id": "R-DME-2162188", "name": "COQ5 methylates MDMQ10H2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [ "R-ALL-2162205" ], "output_participant_list": [], "enzyme_list": [ "Q9VVG6-1", "Q9VMQ5-1", "Q9VYF8-1", "Q9VIF3-1", "Q9W3W4-1" ], "evidence": [ { "id": "R-DME-2162188", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-2162188" } ] }, { "id": "R-DME-2162193", "name": "COQ3 methylates DHDB", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [ "R-ALL-2162209" ], "output_participant_list": [], "enzyme_list": [ "Q9VVG6-1", "Q9VMQ5-1", "Q9VYF8-1", "Q9VIF3-1", "Q9W3W4-1" ], "evidence": [ { "id": "R-DME-2162193", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-2162193" } ] }, { "id": "R-DME-2162194", "name": "COQ7:COQ9 octamer hydroxylates DMQ10H2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial inner membrane, mitochondrial matrix", "input_participant_list": [ "R-ALL-2162204" ], "output_participant_list": [], "enzyme_list": [ "Q9VVG6-1", "Q9VMQ5-1", "Q9VYF8-1", "Q9VIF3-1", "Q9W3W4-1" ], "evidence": [ { "id": "R-DME-2162194", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-2162194" } ] }, { "id": "R-DME-2162195", "name": "COQ4 decarboxylates MHDB", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [ "R-ALL-2162215" ], "output_participant_list": [ "R-ALL-2162208" ], "enzyme_list": [ "Q9VVG6-1", "Q9VMQ5-1", "Q9VYF8-1", "Q9VIF3-1", "Q9W3W4-1" ], "evidence": [ { "id": "R-DME-2162195", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-2162195" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-2162204", "participant_name": "DMQ10H2 [mitochondrial inner membrane]", "crossref": [ { "id": "64181", "database": "ChEBI", "url": "" }, { "id": "ZINC000085599589", "database": "ZINC", "url": "" }, { "id": "HMDB0062428", "database": "HMDB Metabolite", "url": "" } ] }, { "participant_id": "R-ALL-2162205", "participant_name": "MDMQ10H2 [mitochondrial inner membrane]", "crossref": [ { "id": "ZINC000087528822", "database": "ZINC", "url": "" }, { "id": "HMDB0062197", "database": "HMDB Metabolite", "url": "" }, { "id": "64180", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-2162207", "participant_name": "DHB [mitochondrial inner membrane]", "crossref": [ { "id": "84503", "database": "ChEBI", "url": "" }, { "id": "ZINC000085552713", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-2162208", "participant_name": "DMPhOH [mitochondrial inner membrane]", "crossref": [ { "id": "HMDB0060250", "database": "HMDB Metabolite", "url": "" }, { "id": "ZINC000087515526", "database": "ZINC", "url": "" }, { "id": "50774", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-2162209", "participant_name": "DHDB [mitochondrial inner membrane]", "crossref": [ { "id": "62793", "database": "ChEBI", "url": "" }, { "id": "ZINC000087515529", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-2162212", "participant_name": "DeMQ10H2 [mitochondrial inner membrane]", "crossref": [ { "id": "64182", "database": "ChEBI", "url": "" }, { "id": "ZINC000087528826", "database": "ZINC", "url": "" }, { "id": "HMDB0062350", "database": "HMDB Metabolite", "url": "" } ] }, { "participant_id": "R-ALL-2162215", "participant_name": "MHDB [mitochondrial inner membrane]", "crossref": [ { "id": "62796", "database": "ChEBI", "url": "" }, { "id": "ZINC000087515532", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-2162265", "participant_name": "AdoMet [mitochondrial matrix]", "crossref": [ { "id": "59789", "database": "ChEBI", "url": "" }, { "id": "C00019", "database": "COMPOUND", "url": "" }, { "id": "8145813", "database": "PubChem Substance", "url": "" }, { "id": "ZINC000004228231", "database": "ZINC", "url": "" }, { "id": "ZINC000004214738", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-2395501", "participant_name": "(2Fe-2S)2+ [mitochondrial matrix]", "crossref": [ { "id": "33737", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-2395504", "participant_name": "(2Fe-2S)(1+) [mitochondrial matrix]", "crossref": [ { "id": "33738", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "Q9VIF3", "gene_name": "Coq3", "activity": [ { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "Q9VIF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VIF3" } ] }, { "ec_number": "2.1.1.114", "activity": "a 3,4-dihydroxy-5-(all-trans-polyprenyl)benzoate + S-adenosyl-L-methionine = a 4-hydroxy-3-methoxy-5-(all-trans-polyprenyl)benzoate + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "Q9VIF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VIF3" } ] }, { "ec_number": "2.1.1.64", "activity": "3-demethylubiquinol-6 + S-adenosyl-L-methionine = ubiquinol-6 + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "Q9VIF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VIF3" } ] } ] }, { "uniprot_ac": "Q9VMQ5", "gene_name": "Coq6", "activity": [ { "ec_number": "1.14.15.45", "activity": "4-hydroxy-3-(all-trans-octaprenyl)benzoate + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = 3,4-dihydroxy-5-(all-trans-octaprenyl)benzoate + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O.", "evidence": [ { "id": "Q9VMQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMQ5" } ] }, { "ec_number": "1.14.15.46", "activity": "2-methoxy-6-(all-trans-heptaprenyl)phenol + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = 2-methoxy-6-(all-trans-heptaprenyl)benzene-1,4-diol + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O.", "evidence": [ { "id": "Q9VMQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMQ5" } ] }, { "ec_number": "1.14.15.45", "activity": "", "evidence": [ { "id": "Q9VMQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VMQ5" } ] } ] }, { "uniprot_ac": "Q9VVG6", "gene_name": "Coq4", "activity": [ { "ec_number": "4.1.1.130", "activity": "4-hydroxy-3-methoxy-5-(all-trans-hexaprenyl)benzoate + H(+) = 2-methoxy-6-(all-trans-hexaprenyl)phenol + CO2.", "evidence": [ { "id": "Q9VVG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VVG6" } ] } ] }, { "uniprot_ac": "Q9VYF8", "gene_name": "Coq5", "activity": [ { "ec_number": "2.1.1.201", "activity": "2-methoxy-6-(all-trans-nonaprenyl)benzene-1,4-diol + S-adenosyl-L-methionine = 5-methoxy-2-methyl-3-(all-trans-nonaprenyl)benzene-1,4-diol + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "Q9VYF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VYF8" } ] }, { "ec_number": "2.1.1.201", "activity": "", "evidence": [ { "id": "Q9VYF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VYF8" } ] } ] }, { "uniprot_ac": "Q9W3W4", "gene_name": "Coq7", "activity": [ { "ec_number": "1.14.99.60", "activity": "a 5-methoxy-2-methyl-3-(all-trans-polyprenyl)benzene-1,4-diol + AH2 + O2 = a 3-demethylubiquinol + A + H2O.", "evidence": [ { "id": "Q9W3W4", "database": "UniProtKB", "url": 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"https://www.ncbi.nlm.nih.gov/protein/NP_001284957" }, { "id": "Q9W3W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3W9" } ] }, { "name": "Dmel_CG3168", "type": "synonym", "evidence": [ { "id": "Q9W3W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3W9" } ] }, { "name": "LP06294.5prime", "type": "synonym", "evidence": [ { "id": "NP_001284957", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001284957" } ] }, { "name": "Slc22a18", "type": "synonym", "evidence": [ { "id": "NP_001284957", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001284957" }, { "id": "Q9W3W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3W9" } ] } ], "protein_names": [ { "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "Q9W3W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3W9/entry#names_and_taxonomy" } ] }, { "name": "CG3168-PD", "type": "synonym", "evidence": [ { "id": "NP_001284957", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001284957" } ] }, { "name": "uncharacterized protein, isoform D", "type": "synonym", "evidence": [ { "id": "NP_001284957", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001284957" } ] } ], "function": [], "disease": [ { "disease_id": "DOID:0112202", "recommended_name": { "id": "DOID:0112202", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0112202", "name": "developmental and epileptic encephalopathy", "description": "An electroclinical syndrome characterized by epileptiform activity and at least one other pathology that together contribute to cognitive and behavioral impairments including developmental delay or regression with onset anywhere from birth to adulthood." }, "synonyms": [ { "id": "MONDO:0010632", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010632", "name": "developmental and epileptic encephalopathy, 1", "description": "Any early infantile epileptic encephalopathy in which the cause of the disease is a mutation in the ARX gene." }, { "id": "MONDO:0010632", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010632", "name": "ARX early infantile epileptic encephalopathy", "description": "" }, { "id": "MONDO:0010632", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010632", "name": "DEE1", "description": "" }, { "id": "MONDO:0010632", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010632", "name": "EIEE1", "description": "" }, { "id": "MONDO:0010632", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010632", "name": "developmental and epileptic encephalopathy 1, X-linked recessive", "description": "" }, { "id": "MONDO:0010632", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010632", "name": "early infantile epileptic encephalopathy caused by mutation in ARX", "description": "" }, { "id": "MONDO:0010632", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010632", "name": "early infantile epileptic encephalopathy caused by mutation in arx", "description": "" }, { "id": "MONDO:0010632", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010632", "name": "epileptic encephalopathy, early infantile, 1", "description": "" }, { "id": "MONDO:0010632", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010632", "name": "epileptic encephalopathy, early infantile, type 1", "description": "" }, { "id": "MONDO:0010632", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010632", "name": "XMESID", "description": "" }, { "id": "MIM:308350", "resource": "MIM", "url": "https://www.omim.org/entry/308350", "name": "Developmental and epileptic encephalopathy 1", "description": "Developmental and epileptic encephalopathy 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "0112202", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112202" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W3W9", "url": "https://www.uniprot.org/uniprotkb/Q9W3W9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "LP06294.5prime", "url": "https://www.uniprot.org/uniprotkb/Q9W3W9", "locus": { "chromosome": "X", "start_pos": 6720004, "end_pos": 6739986, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0029896", "url": "https://www.ensemblgenomes.org/id/FBgn0029896" } ] } } ], "crossref": [ { "id": "FB:FBgn0029896", "url": "https://alliancegenome.org/gene/FB:FBgn0029896", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0029896", "url": "https://bgee.org/?page=gene&gene_id=FBgn0029896", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0029896", "url": "https://flybase.org/reports/FBgn0029896", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "31612", "url": "https://www.ncbi.nlm.nih.gov/gene/31612", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005829", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005829", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG3168", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3168", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RFQIEFH", "url": "https://omabrowser.org/oma/group/RFQIEFH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W3W9", "url": "https://www.orthodb.org/?gene=Q9W3W9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23511", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23511", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23511:SF34", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23511:SF34", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00083", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00083", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001284957", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001284957", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W3W9", "url": "https://www.uniprot.org/uniprotkb/Q9W3W9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W3W9-1", "url": "https://www.uniprot.org/uniprotkb/Q9W3W9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVEGDSAKGKSEFYNVEAGLQPNYNQSAASNQASNHPTGQANAPATGNATSHIDNRAIIQPYSLGTGPKQPEYQFAADNRGYEPDSHANGKQQDVERDAPDGGHGGHGPPGKGGKGGKGRKKSVPLPEPTAPIVANFERAIELCGYGKFHYILLAICGLVSTSEEMDVISMSFILPSAECDLDLNTETKGWLNSIIFIGMMVGAYFWGSIADSFGRKKVLIVISFMNAFCIVASSFSQTYSFFMLFRFLNGAALGGSGPVIWSYFAEFQPKAKRGSMLSFMAAFWTFGNLFVASLAWLIIPRTIGFTTPYFTYNSWRIFLLVCSLPSFLVGFLLFYLPESPKFLLTRGKKDRALAIFRGIFVTNTKRRPDEYMVYDLEVDEKLLESNGNVKNKYSRMISGMVDHSRALFKSPILRFTIVSITINFTFHIGYYGLLMWFPELFNRFEEYEKAFPDQSAGVCAVTDYVVNLAKEQSNNGTCSSDIPQSVFMESLISLASALPANLLAILGMDMLGRKFFLIAGTMTAGICSALMYFVRSSVQNLVVSAIFSGAISAANAALDCLITEVFPTKLRATGVAISMVAARLGGIIGNIVIAQLLDNYCPSPTFIVSGLLIGGGLMCLLLPNTTRKELN", "length": 632, "header": "tr|Q9W3W9-1|Q9W3W9_DROME Isoform 1 of Major facilitator superfamily (MFS) profile domain-containing protein OS=Drosophila melanogaster OX=7227 GN=LP06294.5prime PE=1 SV=2 CANONICAL=Q9W3W9-1" }, "isoforms": [ { "isoform_ac": "Q9W3W9-1", "url": "https://www.uniprot.org/uniprotkb/Q9W3W9/entry#Q9W3W9-1", "sequence": { "sequence": "MVEGDSAKGKSEFYNVEAGLQPNYNQSAASNQASNHPTGQANAPATGNATSHIDNRAIIQPYSLGTGPKQPEYQFAADNRGYEPDSHANGKQQDVERDAPDGGHGGHGPPGKGGKGGKGRKKSVPLPEPTAPIVANFERAIELCGYGKFHYILLAICGLVSTSEEMDVISMSFILPSAECDLDLNTETKGWLNSIIFIGMMVGAYFWGSIADSFGRKKVLIVISFMNAFCIVASSFSQTYSFFMLFRFLNGAALGGSGPVIWSYFAEFQPKAKRGSMLSFMAAFWTFGNLFVASLAWLIIPRTIGFTTPYFTYNSWRIFLLVCSLPSFLVGFLLFYLPESPKFLLTRGKKDRALAIFRGIFVTNTKRRPDEYMVYDLEVDEKLLESNGNVKNKYSRMISGMVDHSRALFKSPILRFTIVSITINFTFHIGYYGLLMWFPELFNRFEEYEKAFPDQSAGVCAVTDYVVNLAKEQSNNGTCSSDIPQSVFMESLISLASALPANLLAILGMDMLGRKFFLIAGTMTAGICSALMYFVRSSVQNLVVSAIFSGAISAANAALDCLITEVFPTKLRATGVAISMVAARLGGIIGNIVIAQLLDNYCPSPTFIVSGLLIGGGLMCLLLPNTTRKELN", "length": 632, "header": "tr|Q9W3W9-1|Q9W3W9_DROME Isoform 1 of Major facilitator superfamily (MFS) profile domain-containing protein OS=Drosophila melanogaster OX=7227 GN=LP06294.5prime PE=1 SV=2 CANONICAL=Q9W3W9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W3W9", "url": "https://www.uniprot.org/uniprotkb/Q9W3W9" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W3W9", "url": "https://www.uniprot.org/uniprotkb/Q9W3W9" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3W9", "url": "https://www.uniprot.org/uniprotkb/Q9W3W9" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3W9", "url": "https://www.uniprot.org/uniprotkb/Q9W3W9" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W3W9", "url": "https://www.uniprot.org/uniprotkb/Q9W3W9" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W3W9", "url": "https://www.uniprot.org/uniprotkb/Q9W3W9" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W3W9", "url": "https://www.uniprot.org/uniprotkb/Q9W3W9" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3W9", "url": "https://www.uniprot.org/uniprotkb/Q9W3W9" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W3W9", "url": "https://www.uniprot.org/uniprotkb/Q9W3W9" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W3W9", "url": "https://www.uniprot.org/uniprotkb/Q9W3W9" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W3W9", "url": "https://www.uniprot.org/uniprotkb/Q9W3W9" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG3168", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3168", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286Y8C7-1", "protein_name": "Synaptic vesicle glycoprotein 2Ca isoform X1", "gene_name": "sv2ca", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDETAPQDTSSLMKGARDIAKVAKKQAVKKVNKVVDRASDEYSQNRAYQRFQDEDDDYYSQPDGNYTSHQANDEEGSSDATEGHDDEDEIYEGEYQGIPSDAKARDGQVALGQPLSDGLKDRRELENERQADEEELAQQYELIIQECGHGRFQWQLFFTLGLALMSDGVEVFVVGFVLPSAETDMCVPDSSSGWLGSIVYLGMMVGAFFWGGMADKVGRRQCLLICMSLNGFFAFLSSFVQGYGLFLLCRMIAGFGIGGAVPIVFSYFAEVLAREKRGEHLSWLCMFWMIGEIYASAMAWAIIPHYGWSFSMGSAYQFHSWRVFVVVCALPCVCAVVALTFMPESPRFYLEVGKHDEAWMILKQIHDTNMRARGQPEKVFTVNRIKIPKQIDEFVEMHESGNFFSKAIFRIKTELHGIWLNFLKCFNYPVKESTVKLAIVWLTLSFGYYGLSVWFPDVIKHLQNDEYASKGQRHNNERIEDFTFNFTLENQIHTNSLFINDRFINMKFKSVTFINSTFQSCFFEDVTSVGSFFRNCTFIEAVFYNTDIDDSKLKNTDVINSTFYHNKTGCQMTFEDDYSAYWVYFVNFLGTLAVLPGNIVSALLMDKIGRLSMLGFSMILSGISCFFLWFGTSESMMIGMLCLYNGLSISAWNSLDVVTTELYPTDRRGTGFGFCNALCKLAAVMGNLIFGSLVGITKAIPILLASSVLVGGGLVGLRLPDTRSNVLM", "length": 728 }, "evidence": [ { "id": "HGNC:30670", "url": "https://alliancegenome.org/gene/HGNC:30670#orthology", "database": "AGR" }, { "id": "MGI:1922459", "url": "https://alliancegenome.org/gene/MGI:1922459#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7F6Z2-1", "protein_name": "Synaptic vesicle glycoprotein 2A", "gene_name": "sv2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDEGYRDRSAFIKGAKDIAKEVKRHAGKKVGRHVDKMTDEYTKRSYTRFEEDDDDDDYPVQAQDGSYYRSNSRANDDEGAHSDSTEGHDEDDEIYEGEYQGIPRNDSVEKADRQVGAVGQSQFRDMTQYEGERRKDQEELAQQYETILQECGHGRFQWTLYFVLGLALMADGVEIFVVGFVLPSAEKDMCLSEPNKGMLGLIVYLGMMVGAFVWGGLADRIGRRQTLLISLSINSVFAFFSSFVQGYSSFLFCRLLSGVGIGGSIPIVFSYYSEFLAQEKRGEHLSWLCMFWMIGGIYAAAMAWAIIPHYGWSFQMGSAYQFHSWRVFVLVCAFPSVAAIAALTTMPESPRFYLENGKHDEAWMILKQVHDTNMRAKGYPERVFSVTTIKTVKQMDELVDMGGEATAWHQRWRIKLTNLFHQVWGNFLTVFNPEYRRITYMMMAVWFSMSFSYYGLTVWFPDMIKYLQKQEYSSRTKVFIKEKVEHVTFNFTLENQIHRNGEYFNNKFLNLKMKSMVFEDSLFEECYFEDITSSNTFFRNCTFISTLFYNTDLFKYRLINSKLINSTFLHNKEGCMLDFSDENNAYMIYFVSFLGTLAVLPGNIVSALLMDKIGRLRMLAGSSVISCVSCFFLSFGNSESAMIALLCLFGGISIASWNALDVLTVELYPSDKRTTAFGFLNALCKLAAVLGISIFQSFVGITKAVPILFASGALAAGSFLALKLPETRGQVLQ", "length": 733 }, "evidence": [ { "id": "HGNC:20566", "url": "https://alliancegenome.org/gene/HGNC:20566#orthology", "database": "AGR" }, { "id": "MGI:1927139", "url": "https://alliancegenome.org/gene/MGI:1927139#orthology", "database": "AGR" }, { "id": "RGD:619715", "url": "https://alliancegenome.org/gene/RGD:619715#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P25297-1", "protein_name": "Inorganic phosphate transporter PHO84", "gene_name": "PHO84", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSSVNKDTIHVAERSLHKEHLTEGGNMAFHNHLNDFAHIEDPLERRRLALESIDDEGFGWQQVKTISIAGVGFLTDSYDIFAINLGITMMSYVYWHGSMPGPSQTLLKVSTSVGTVIGQFGFGTLADIVGRKRIYGMELIIMIVCTILQTTVAHSPAINFVAVLTFYRIVMGIGIGGDYPLSSIITSEFATTKWRGAIMGAVFANQAWGQISGGIIALILVAAYKGELEYANSGAECDARCQKACDQMWRILIGLGTVLGLACLYFRLTIPESPRYQLDVNAKLELAAAAQEQDGEKKIHDTSDEDMAINGLERASTAVESLDNHPPKASFKDFCRHFGQWKYGKILLGTAGSWFTLDVAFYGLSLNSAVILQTIGYAGSKNVYKKLYDTAVGNLILICAGSLPGYWVSVFTVDIIGRKPIQLAGFIILTALFCVIGFAYHKLGDHGLLALYVICQFFQNFGPNTTTFIVPGECFPTRYRSTAHGISAASGKVGAIIAQTALGTLIDHNCARDGKPTNCWLPHVMEIFALFMLLGIFTTLLIPETKRKTLEEINELYHDEIDPATLNFRNKNNDIESSSPSQLQHEA", "length": 587 }, "evidence": [ { "id": "FB:FBgn0029896", "url": "https://alliancegenome.org/gene/FB:FBgn0029896#orthology", "database": "AGR" }, { "id": "SGD:S000004592", "url": "https://alliancegenome.org/gene/SGD:S000004592#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q02563-1", "protein_name": "Synaptic vesicle glycoprotein 2A", "gene_name": "Sv2a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEEGFRDRAAFIRGAKDIAKEVKKHAAKKVVKGLDRVQDEYSRRSYSRFEEEEDDDDFPAPADGYYRGEGAQDEEEGGASSDATEGHDEDDEIYEGEYQGIPRAESGGKGERMADGAPLAGVRGGLSDGEGPPGGRGEAQRRKDREELAQQYETILRECGHGRFQWTLYFVLGLALMADGVEVFVVGFVLPSAEKDMCLSDSNKGMLGLIVYLGMMVGAFLWGGLADRLGRRQCLLISLSVNSVFAFFSSFVQGYGTFLFCRLLSGVGIGGSIPIVFSYFSEFLAQEKRGEHLSWLCMFWMIGGVYAAAMAWAIIPHYGWSFQMGSAYQFHSWRVFVLVCAFPSVFAIGALTTQPESPRFFLENGKHDEAWMVLKQVHDTNMRAKGHPERVFSVTHIKTIHQEDELIEIQSDTGTWYQRWGVRALSLGGQVWGNFLSCFSPEYRRITLMMMGVWFTMSFSYYGLTVWFPDMIRHLQAVDYAARTKVFPGERVEHVTFNFTLENQIHRGGQYFNDKFIGLRLKSVSFEDSLFEECYFEDVTSSNTFFRNCTFINTVFYNTDLFEYKFVNSRLVNSTFLHNKEGCPLDVTGTGEGAYMVYFVSFLGTLAVLPGNIVSALLMDKIGRLRMLAGSSVLSCVSCFFLSFGNSESAMIALLCLFGGVSIASWNALDVLTVELYPSDKRTTAFGFLNALCKLAAVLGISIFTSFVGITKAAPILFASAALALGSSLALKLPETRGQVLQ", "length": 742 }, "evidence": [ { "id": "FB:FBgn0029896", "url": "https://alliancegenome.org/gene/FB:FBgn0029896#orthology", "database": "AGR" }, { "id": "HGNC:20566", "url": "https://alliancegenome.org/gene/HGNC:20566#orthology", "database": "AGR" }, { "id": "MGI:1927139", "url": "https://alliancegenome.org/gene/MGI:1927139#orthology", "database": "AGR" }, { "id": "RGD:619715", "url": "https://alliancegenome.org/gene/RGD:619715#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q1LVS8-1", "protein_name": "Putative transporter SVOPL", "gene_name": "svopl", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MALKRSSSMKTQLVDAIQLEEVEMEEEITTTSNNNNPVEPAQVKEPKCYTVEEAVESIGFGCFHILLFVIMGSANIVEAMEIMLLAVVSPEIRCEWHLEDWQVALVSTMVFFGFMVCGVLCGYIADKYGRWKVVFGGFVWASYFSFLTSFSTSYGWFIFLRCMVGCGVAATSQGFVLKTEFIPAKYRAYLLPLASIFWMMGSILIIVLGMTVVPTMGWRWMIRFSVIPSLVLIGLFMFIPESARFQVSAGNIQGAMSTLKRIAKMNNGVLPEGELREPEVTERGNAVTLISSAFRRTSLLLWYSWFVASFSYYGSVLSSSELLEKNLLCVTDPDLEHQIKHIQEETLCYCIPFNSDDYQTLLISCLGEVALIPLNIILLNIVGRKYSMVILLLLSAFFFMLVNICTTMLGFTILLFLLRSVVSMNFNVVYIYTAEVYPTSVRSIGMGFCTSFSRIGGMIAPFIAQVLMSKSVILALSPFATACIICAIGVFFLPIETRGRALLQDA", "length": 506 }, "evidence": [ { "id": "SGD:S000004592", "url": "https://alliancegenome.org/gene/SGD:S000004592#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q496J9-1", "protein_name": "Synaptic vesicle glycoprotein 2C", "gene_name": "SV2C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDSYKDRTSLMKGAKDIAREVKKQTVKKVNQAVDRAQDEYTQRSYSRFQDEEDDDDYYPAGETYNGEANDDEGSSEATEGHDEDDEIYEGEYQGIPSMNQAKDSIVSVGQPKGDEYKDRRELESERRADEEELAQQYELIIQECGHGRFQWALFFVLGMALMADGVEVFVVGFVLPSAETDLCIPNSGSGWLGSIVYLGMMVGAFFWGGLADKVGRKQSLLICMSVNGFFAFLSSFVQGYGFFLFCRLLSGFGIGGAIPTVFSYFAEVLAREKRGEHLSWLCMFWMIGGIYASAMAWAIIPHYGWSFSMGSAYQFHSWRVFVIVCALPCVSSVVALTFMPESPRFLLEVGKHDEAWMILKLIHDTNMRARGQPEKVFTVNKIKTPKQIDELIEIESDTGTWYRRCFVRIRTELYGIWLTFMRCFNYPVRDNTIKLTIVWFTLSFGYYGLSVWFPDVIKPLQSDEYALLTRNVERDKYANFTINFTMENQIHTGMEYDNGRFIGVKFKSVTFKDSVFKSCTFEDVTSVNTYFKNCTFIDTVFDNTDFEPYKFIDSEFKNCSFFHNKTGCQITFDDDYSAYWIYFVNFLGTLAVLPGNIVSALLMDRIGRLTMLGGSMVLSGISCFFLWFGTSESMMIGMLCLYNGLTISAWNSLDVVTVELYPTDRRATGFGFLNALCKAAAVLGNLIFGSLVSITKSIPILLASTVLVCGGLVGLCLPDTRTQVLM", "length": 727 }, "evidence": [ { "id": "FB:FBgn0029896", "url": "https://alliancegenome.org/gene/FB:FBgn0029896#orthology", "database": "AGR" }, { "id": "RGD:619718", "url": "https://alliancegenome.org/gene/RGD:619718#orthology", "database": "AGR" }, { "id": "HGNC:30670", "url": "https://alliancegenome.org/gene/HGNC:30670#orthology", "database": "AGR" }, { "id": "MGI:1922459", "url": "https://alliancegenome.org/gene/MGI:1922459#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q63564-1", "protein_name": "Synaptic vesicle glycoprotein 2B", "gene_name": "Sv2b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDDYRYRDNYEGYAPNDGYYRGNEQNPEEDAQSDVTEGHDEEDEIYEGEYQGIPHPDDVKSKQTKMAPSRADGLRGQADLMAERMEDEEQLAHQYETIIDECGHGRFQWTLFFVLVLALMADGVEVFVVSFALPSAEKDMCLSSSKKGMLGLIVYLGMMAGAFILGGLADKLGRKKVLSMSLAINASFASLSSFVQGYGAFLFCRLISGIGIGGSLPIVFAYFSEFLSREKRGEHLSWLGIFWMTGGIYASAMAWSIIPHYGWGFSMGTNYHFHSWRVFVIVCALPATVSMVALKFMPESPRFLLEMGKHDEAWMILKQVHDTNMRAKGTPEKVFTVSHIKTPKQMDEFIEIQSSTGTWYQRWLVRFMTIFKQVWDNALYCVMGPYRMNTLILAVVWFTMALSYYGLTVWFPDMIRYFQDEEYKSKMKVFFGEHVHGATINFTMENQIHQHGKLVNDKFIKMYFKHVLFEDTFFDKCYFEDVTSTDTYFKNCTIESTTFYNTDLYKHKFIDCRFINSTFLEQKEGCHMDFEEDNDFLIYLVSFLGSLSVLPGNIISALLMDRIGRLKMIGGSMLISAVCCFFLFFGNSESAMIGWQCLFCGTSIAAWNALDVITVELYPTNQRATAFGILNGLCKLGAILGNTIFASFVGITKVVPILLAAASLVGGGLVALRLPETREQVLM", "length": 683 }, "evidence": [ { "id": "FB:FBgn0029896", "url": "https://alliancegenome.org/gene/FB:FBgn0029896#orthology", "database": "AGR" }, { "id": "HGNC:16874", "url": "https://alliancegenome.org/gene/HGNC:16874#orthology", "database": "AGR" }, { "id": "MGI:1927338", "url": "https://alliancegenome.org/gene/MGI:1927338#orthology", "database": "AGR" }, { "id": "RGD:619716", "url": "https://alliancegenome.org/gene/RGD:619716#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q69ZS6-1", "protein_name": "Synaptic vesicle glycoprotein 2C", "gene_name": "Sv2c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDSYKDRTSLMKGAKDIAKEVKKQTVKKVNQAVDRAQDEYTQRSYSRFQDEEDDDDYYPPGETYSGEVNDDEGSSEATEGHDEEDEIYEGEYQGIPSTNQGKDSIVSVGQPKGDEYKDRRELESERRADEEELAQQYELIIQECGHGRFQWALFFVLGMALMADGVEVFVVGFVLPSAETDLCIPNSGSGWLGSIVYLGMMVGAFFWGGLADKVGRKQSLLICMSVNGFFAFLSSFVQGYGFFLVCRLLSGFGIGGAIPTVFSYFAEVLAREKRGEHLSWLCMFWMIGGIYASAMAWAIIPHYGWSFSMGSAYQFHSWRVFVIVCALPCVSSVVALTFMPESPRFLLEVGKHDEAWMILKLIHDTNMRARGQPEKVFTVNKIKTPKQIDELIEIESDTGTWYRRCFVRIRTELYGIWLTFMRCFNYPVRENTIKLTIVWFTLSFGYYGLSVWFPDVIKHLQSDEYALLTRNVQKDKYANFSINFTMENQIHTGMEYENGRFLGVKFKSVTFKDSVFKSCTFDDVTSVNTYFKNCTFIDTLFDNTDFEPYKFIDSEFQNCSFLHNKTGCQITFDDDYSAYWIYFVNFLGTLAVLPGNIVSALLMDRIGRLTMLGGSMVLSGISCFFLWFGTSESMMIGMLCLYNGLTISAWNSLDVVTVELYPTDRRATGFGFLNALCKAAAVLGNLIFGSLVSITKAIPILLASTVLVCGGLVGLRLPDTRTQVLM", "length": 727 }, "evidence": [ { "id": "FB:FBgn0029896", "url": "https://alliancegenome.org/gene/FB:FBgn0029896#orthology", "database": "AGR" }, { "id": "RGD:619718", "url": "https://alliancegenome.org/gene/RGD:619718#orthology", "database": "AGR" }, { "id": "HGNC:30670", "url": "https://alliancegenome.org/gene/HGNC:30670#orthology", "database": "AGR" }, { "id": "MGI:1922459", "url": "https://alliancegenome.org/gene/MGI:1922459#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6PDF3-1", "protein_name": "Putative transporter SVOPL", "gene_name": "Svopl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAKQTEPVTIISLRKLSQAAPEPQQKETKTFTVEDAVETIGFGRFHIALFLIMGSTGVVEAMEIMLIAVVSPVIRCEWQLENWQVAFVTTMVFFGYMVSSILFGLLADRYGRWKILLLSFLWGAYFSLLTSFSPSYIWFVFLRTMVGCGVSGHAQGLIIKTEFLPTKYRGYMLPLSQVFWLAGSLLIISMASVVIPTIGWRWLIRIASIPGIILIMAFKFIPESARFNVSTGNTQAALNTLESIAKMNRSVMPEGQLVEPILEKRGRFADLLDSKYLRTTLQIWIIWLGISFAYYGVILASAELLERDLVCGSKSESEPEVVETTGDSGEGLSPCYCHIFAPSDYRTMIISTLGEIALNPLNILGINFLGRRLSLSITMGCTALFFLLLNICTSSAGLIGFLFMLRALVAANFNTIYIYTAEVYPTPMRAIGMGTSGSLCRIGAMVAPFISQVLMSASFLGALCLFSSVCVVCAISAFTLPIETKGRALQQIK", "length": 494 }, "evidence": [ { "id": "SGD:S000004592", "url": "https://alliancegenome.org/gene/SGD:S000004592#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7L0J3-1", "protein_name": "Synaptic vesicle glycoprotein 2A", "gene_name": "SV2A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEGFRDRAAFIRGAKDIAKEVKKHAAKKVVKGLDRVQDEYSRRSYSRFEEEDDDDDFPAPSDGYYRGEGTQDEEEGGASSDATEGHDEDDEIYEGEYQGIPRAESGGKGERMADGAPLAGVRGGLSDGEGPPGGRGEAQRRKEREELAQQYEAILRECGHGRFQWTLYFVLGLALMADGVEVFVVGFVLPSAEKDMCLSDSNKGMLGLIVYLGMMVGAFLWGGLADRLGRRQCLLISLSVNSVFAFFSSFVQGYGTFLFCRLLSGVGIGGSIPIVFSYFSEFLAQEKRGEHLSWLCMFWMIGGVYAAAMAWAIIPHYGWSFQMGSAYQFHSWRVFVLVCAFPSVFAIGALTTQPESPRFFLENGKHDEAWMVLKQVHDTNMRAKGHPERVFSVTHIKTIHQEDELIEIQSDTGTWYQRWGVRALSLGGQVWGNFLSCFGPEYRRITLMMMGVWFTMSFSYYGLTVWFPDMIRHLQAVDYASRTKVFPGERVEHVTFNFTLENQIHRGGQYFNDKFIGLRLKSVSFEDSLFEECYFEDVTSSNTFFRNCTFINTVFYNTDLFEYKFVNSRLINSTFLHNKEGCPLDVTGTGEGAYMVYFVSFLGTLAVLPGNIVSALLMDKIGRLRMLAGSSVMSCVSCFFLSFGNSESAMIALLCLFGGVSIASWNALDVLTVELYPSDKRTTAFGFLNALCKLAAVLGISIFTSFVGITKAAPILFASAALALGSSLALKLPETRGQVLQ", "length": 742 }, "evidence": [ { "id": "FB:FBgn0029896", "url": "https://alliancegenome.org/gene/FB:FBgn0029896#orthology", "database": "AGR" }, { "id": "HGNC:20566", "url": "https://alliancegenome.org/gene/HGNC:20566#orthology", "database": "AGR" }, { "id": "MGI:1927139", "url": "https://alliancegenome.org/gene/MGI:1927139#orthology", "database": "AGR" }, { "id": "RGD:619715", "url": "https://alliancegenome.org/gene/RGD:619715#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7L1I2-1", "protein_name": "Synaptic vesicle glycoprotein 2B", "gene_name": "SV2B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDDYKYQDNYGGYAPSDGYYRGNESNPEEDAQSDVTEGHDEEDEIYEGEYQGIPHPDDVKAKQAKMAPSRMDSLRGQTDLMAERLEDEEQLAHQYETIMDECGHGRFQWILFFVLGLALMADGVEVFVVSFALPSAEKDMCLSSSKKGMLGMIVYLGMMAGAFILGGLADKLGRKRVLSMSLAVNASFASLSSFVQGYGAFLFCRLISGIGIGGALPIVFAYFSEFLSREKRGEHLSWLGIFWMTGGLYASAMAWSIIPHYGWGFSMGTNYHFHSWRVFVIVCALPCTVSMVALKFMPESPRFLLEMGKHDEAWMILKQVHDTNMRAKGTPEKVFTVSNIKTPKQMDEFIEIQSSTGTWYQRWLVRFKTIFKQVWDNALYCVMGPYRMNTLILAVVWFAMAFSYYGLTVWFPDMIRYFQDEEYKSKMKVFFGEHVYGATINFTMENQIHQHGKLVNDKFTRMYFKHVLFEDTFFDECYFEDVTSTDTYFKNCTIESTIFYNTDLYEHKFINCRFINSTFLEQKEGCHMDLEQDNDFLIYLVSFLGSLSVLPGNIISALLMDRIGRLKMIGGSMLISAVCCFFLFFGNSESAMIGWQCLFCGTSIAAWNALDVITVELYPTNQRATAFGILNGLCKFGAILGNTIFASFVGITKVVPILLAAASLVGGGLIALRLPETREQVLM", "length": 683 }, "evidence": [ { "id": "FB:FBgn0029896", "url": "https://alliancegenome.org/gene/FB:FBgn0029896#orthology", "database": "AGR" }, { "id": "HGNC:16874", "url": "https://alliancegenome.org/gene/HGNC:16874#orthology", "database": "AGR" }, { "id": "MGI:1927338", "url": "https://alliancegenome.org/gene/MGI:1927338#orthology", "database": "AGR" }, { "id": "RGD:619716", "url": "https://alliancegenome.org/gene/RGD:619716#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BG39-1", "protein_name": "Synaptic vesicle glycoprotein 2B", "gene_name": "Sv2b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDDYRYRDNYEGYAPSDGYYRSNEQNQEEDAQSDVTEGHDEEDEIYEGEYQGIPHPDDVKSKQTKMAPSRADGLGGQADLMAERMEDEEELAHQYETIIDECGHGRFQWTLFFVLGLALMADGVEIFVVSFALPSAEKDMCLSSSKKGMLGLIVYLGMMAGAFILGGLADKLGRKKVLSMSLAINASFASLSSFVQGYGAFLFCRLISGIGIGGSLPIVFAYFSEFLSREKRGEHLSWLGIFWMTGGIYASAMAWSIIPHYGWGFSMGTNYHFHSWRVFVIVCALPATVSMVALKFMPESPRFLLEMGKHDEAWMILKQVHDTNMRAKGTPEKVFTVSHIKTPKQMDEFIEIQSSTGTWYQRWLVRFMTIFKQVWDNALYCVMGPYRMNTLILAVVWFTMALSYYGLTVWFPDMIRYFQDEEYKSKMKVFFGEHVHGATINFTMENQIHQHGKLVNDKFIKMYFKHVLFEDTFFDKCYFEDVTSTDTYFKNCTIESTTFYNTDLYKHKFINCRFINSTFLEQKEGCHMDFEEDNDFLIYLVSFLGSLSVLPGNIISALLMDRIGRLKMIGGSMLISAVCCFFLFFGNSESAMIGWQCLFCGTSIAAWNALDVITVELYPTNQRATAFGILNGLCKFGAILGNTIFASFVGITKVVPILLAAASLVGGGLIALRLPETREQVLM", "length": 683 }, "evidence": [ { "id": "FB:FBgn0029896", "url": "https://alliancegenome.org/gene/FB:FBgn0029896#orthology", "database": "AGR" }, { "id": "HGNC:16874", "url": "https://alliancegenome.org/gene/HGNC:16874#orthology", "database": "AGR" }, { "id": "MGI:1927338", "url": "https://alliancegenome.org/gene/MGI:1927338#orthology", "database": "AGR" }, { "id": "RGD:619716", "url": "https://alliancegenome.org/gene/RGD:619716#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q91WU2-1", "protein_name": "Solute carrier family 22 member 7", "gene_name": "Slc22a7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGFEELLHKVGGFGPFQLRNLVLLALPRFLLPMHFLLPIFMAAVPAHHCALPDAPANLSHQDLWLKTHLPRETDGSFSSCLRFAYPQALPNVTLGTEVYNSGEPEGEPLTVPCSQGWEYDRSEFSSTIATEWDLVCEQRGLNKVTSTCFFIGVLLGAVVYGYLSDRFGRRRLLLVAYVSTLALGLMSAASVNYIMFVTTRMLTGSALAGFTIIVLPLELEWLDVEHRTVAGVISTTFWTGGVLLLTLVGYLIRSWRWLLLAATLPCVPGIISIWWVPESARWLLTQGRVEEAKKYLSICAKLNGRPISEDSLSQEALNKVITMERVSQRPSYLDLFRTSQLRHVSLCCMMMWFGVNFSYYGLTLDASGLGLTVYQTQLLFGAVEVPSKITVFFLVRLVGRRLTEAGMLLATALTFGISLLVSSDTKSWITALVVIGKAFSEAAFTTAYLFTSELYPTVLRQTGMGFTALIGRLGASLAPLVVLLDGVWLLLPKLAYGGISFLAACTVLLLPETKKAQLPETIQDVERKGRKIDRSGTELA", "length": 540 }, "evidence": [ { "id": "SGD:S000004592", "url": "https://alliancegenome.org/gene/SGD:S000004592#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JIS5-1", "protein_name": "Synaptic vesicle glycoprotein 2A", "gene_name": "Sv2a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEEGFRDRAAFIRGAKDIAKEVKKHAAKKVVKGLDRVQDEYSRRSYSRFEEEDDDDDFPAPADGYYRGEGAQDEEEGGASSDATEGHDEDDEIYEGEYQGIPRAESGGKGERMADGAPLAGVRGGLSDGEGPPGGRGEAQRRKDREELAQQYETILRECGHGRFQWTLYFVLGLALMADGVEVFVVGFVLPSAEKDMCLSDSNKGMLGLIVYLGMMVGAFLWGGLADRLGRRQCLLISLSVNSVFAFFSSFVQGYGTFLFCRLLSGVGIGGSIPIVFSYFSEFLAQEKRGEHLSWLCMFWMIGGVYAAAMAWAIIPHYGWSFQMGSAYQFHSWRVFVLVCAFPSVFAIGALTTQPESPRFFLENGKHDEAWMVLKQVHDTNMRAKGHPERVFSVTHIKTIHQEDELIEIQSDTGTWYQRWGVRALSLGGQVWGNFLSCFSPEYRRITLMMMGVWFTMSFSYYGLTVWFPDMIRHLQAVDYAARTKVFPGERVEHVTFNFTLENQIHRGGQYFNDKFIGLRLKSVSFEDSLFEECYFEDVTSSNTFFRNCTFINTVFYNTDLFEYKFVNSRLVNSTFLHNKEGCPLDVTGTGEGAYMVYFVSFLGTLAVLPGNIVSALLMDKIGRLRMLAGSSVLSCVSCFFLSFGNSESAMIALLCLFGGVSIASWNALDVLTVELYPSDKRTTAFGFLNALCKLAAVLGISIFTSFVGITKAAPILFASAALALGSSLALKLPETRGQVLQ", "length": 742 }, "evidence": [ { "id": "FB:FBgn0029896", "url": "https://alliancegenome.org/gene/FB:FBgn0029896#orthology", "database": "AGR" }, { "id": "HGNC:20566", "url": "https://alliancegenome.org/gene/HGNC:20566#orthology", "database": "AGR" }, { "id": "MGI:1927139", "url": "https://alliancegenome.org/gene/MGI:1927139#orthology", "database": "AGR" }, { "id": "RGD:619715", "url": "https://alliancegenome.org/gene/RGD:619715#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VCA2-1", "protein_name": "Organic cation transporter protein", "gene_name": "Orct", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGYDDVITHLGEFGPYQKRIYYLLCLPAIVCAFHKLAGVFLLAKPDFRCALPYENGSIYELSPHLWNLSYPENERCSYYDVDYTEEYLNGSIPRSSNETKTCSSYVYDRSKYLNSAVTEWNLVCSRSLLSATSDSLFMLGVLLGSLIFGQMSDKLGRKPTFFASLVLQLIFGVLAAVAPEYFSYTISRMIVGATTSGVFLVAYVIALEMVGSSYRLFAGVAMQMFFSVGFMLTAGFAYFIHDWRWLQIAITLPGLLFLCYYWIIPESARWLLMKGRKDEAFVIIEKAAKENKVEVPNEIYEQLVDEVAEKKKQDEMAASQPAATVFDLLRYPNLRRKTLLIFFDWFVNSGVYYGLSWNTNNLGGNQLVNFMISGAVEIPGYTLLLFTLNRWGRRSILCGTMMVAGISLLATIFVPSDMNWLIVACAMIGKLAITSSYGTIYIFSAEQFPTVVRNVGLGASSMVARVGGILAPYLKLLGEIWRPLPLIICGALSLTAGLLSLLLPETLNKPMPETIEDGENFGKKPAPQETAEEGGTQELSGMLNGKSG", "length": 548 }, "evidence": [ { "id": "SGD:S000004592", "url": "https://alliancegenome.org/gene/SGD:S000004592#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9WTN6-1", "protein_name": "Solute carrier family 22 member 21", "gene_name": "Slc22a21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLDYDEVTAFLGEWGTFQRLIFFLLSASIIPNGFTGLSAVFLTAIPEHRCRIPDTVNLSSAWRNHSIPMETKDGPEVPQKCRRYRLATIANFSELGLEPGRDVDLEQLEQENCLDGWEYDKDIFLSTIVTEWDLVCKDDWKAPLTTSFFYVGVLLGSFISGQLSDRFGRKNILFLTMAMHTGFSFIQVFSVNFEMFTLLYTLVGMGHISNYVAAFVLGTEMLSKSVRIIFATLGVCIFFAFGFMVLPLFAYFIREWRRLLLAITLPGVLCGALWWFIPESPRWLISQGRIKEAEVIIRKAAKINGIVAPSTIFDPSETNKLQDDSSKKPQSHHIYDLVRTPNIRILTIMSIILWLTISVGYFGLSLDTPNLNGNIYVNCFLLAAVEVPAYVLAWLLLQHVSRRYSMAGSLFLGGSVLLLVQLVPSDLHYLSTTLVMVGKFGITSAYSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRRLPYILMGSLTILTAIITLFFPESSGVSLPETIDEMQKVKKLKQRQSLSKKGSPKESKGNVSRTSRTSEPKGF", "length": 564 }, "evidence": [ { "id": "SGD:S000004592", "url": "https://alliancegenome.org/gene/SGD:S000004592#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Z0E8-1", "protein_name": "Organic cation/carnitine transporter 2", "gene_name": "Slc22a5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRDYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFNGMSIVFLAGTPEHRCLVPHTVNLSSAWRNHSIPLETKDGRQVPQKCRRYRLATIANFSELGLEPGRDVDLEQLEQESCLDGWEYDKDVFLSTIVTEWDLVCKDDWKAPLTTSLFFVGVLMGSFISGQLSDRFGRKNVLFLTMGMQTGFSFLQVFSVNFEMFTVLFVLVGMGQISNYVAAFVLGTEILSKSIRIIFATLGVCIFYAFGFMVLPLFAYFIRDWRMLLLALTVPGVLCGALWWFIPESPRWLISQGRIKEAEVIIRKAAKINGIVAPSTIFDPSELQDLNSTKPQLHHIYDLIRTRNIRVITIMSIILWLTISVGYFGLSLDTPNLHGDIYVNCFLLAAVEVPAYVLAWLLLQYLPRRYSISAALFLGGSVLLFMQLVPSELFYLSTALVMVGKFGITSAYSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRFLPYILMGSLTILTAILTLFFPESFGVPLPDTIDQMLRVKGIKQWQIQSQTRMQKDGEESPTVLKSTAF", "length": 557 }, "evidence": [ { "id": "SGD:S000004592", "url": "https://alliancegenome.org/gene/SGD:S000004592#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Z2I6-1", "protein_name": "Synaptic vesicle glycoprotein 2C", "gene_name": "Sv2c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEDSYKDRTSLMKGAKDIAKEVKKQTVKKVNQAVDRAQDEYTQRSYSRFQDEDDDDDYYPPGETYSGEANDDEGSSEATEGHDEEDEIYEGEYQGIPSTNQGKDSIVSVGQPKGDEYKDRRELESERRADEEELAQQYELIIQECGHGRFQWALFFVLGMALMADGVEVFVVGFVLPSAETDLCIPNSGSGWLGSIVYLGMMVGAFFWGGLADKVGRKQSLLICMSVNGFFAFLSSFVQGYGFFLLCRLLSGFGIGGAIPTVFSYFAEVLAREKRGEHLSWLCMFWMIGGIYASAMAWAIIPHYGWSFSMGSAYQFHSWRVFVIVCALPCVSSVVALTFMPESPRFLLEVGKHDEAWMILKLIHDTNMRARGQPEKVFTVNKIKTPKQIDELIEIESDTGTWYRRCFVRIRTELYGIWLTFMRCFNYPVRENTIKLTIVWFTLSFGYYGLSVWFPDVIKHLQSDEYALLTRNVQKDKYANFSINFTMENQVHTGMEYDNGRFLGVKFKSVTFKDSVFKSCTFDDVTSVNTYFKNCTFIDTLFENTDFEPYKFIDSEFQNCSFLHNKTGCQITFDDDYSAYWIYFVNFLGTLAVLPGNIVSALLMDRIGRLTMLGGSMVLSGISCFFLWFGTSESMMIGMLCLYNGLTISAWNSLDVVTVELYPTDRRATGFGFLNALCKAAAVLGNLIFGSLVSITKAIPILLASTVLVCGGLVGLRLPDTRTQVLM", "length": 727 }, "evidence": [ { "id": "FB:FBgn0029896", "url": "https://alliancegenome.org/gene/FB:FBgn0029896#orthology", "database": "AGR" }, { "id": "RGD:619718", "url": "https://alliancegenome.org/gene/RGD:619718#orthology", "database": "AGR" }, { "id": "HGNC:30670", "url": "https://alliancegenome.org/gene/HGNC:30670#orthology", "database": "AGR" }, { "id": "MGI:1922459", "url": "https://alliancegenome.org/gene/MGI:1922459#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "X1WCQ3-1", "protein_name": "Synaptic vesicle glycoprotein 2B", "gene_name": "sv2bb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADPYQNNIYHQGDGDSYGTYGQGGQDGYGYQTDYPPQEEDAASDATEGHDEDDQMYEGEYQGIPHPDEVKAARRAARAKARTPTDTVSELEELAEQYEDIMEDCGHGKFQWTLFVVLGLALMADSVECFVVALVLPSAEKDMCLSHAEKGMLGLIVFLGMMFGAFIWGGLADKVGRRKCLIIVLAMNCISAFFSSFAQGYGFFLFFRLFSGIGIGGSVPIVYSYFSEFLQMDKRGEHLSWLCMFWMMGGIYASFTAWGIIPRYGWGFSMGTEFQFHSWRVFVLVCALPAIAAFVGLMFMPESPRFLLENAKHDEAWMILKQVHDTNWRAKGQPEKVFTVTQIRTPKTQEDEFIEIQTATGTAFQRWVVRTLTLTKLVIKNVLSLFGRELRLATLLMAIIWFTMAFSYYGLSVWFPDMIKHLQHEEYESKVKVFHREKVEQFHFNFSLENQVHKEGEYINDKFINIEMKSVKFEDSLFVDCFFENVRSTETMFENCTIRSTVFYDTDLYEEKFIDCTMENVTFLHNKKGCHLDYEEDNDVLIYLVSFLGSLAVLPGNIISALFMDKIGRIKIIGGSMLVSAGCTFFLFLSFSQAAIIAWQCLFYGVSVAAWNGIQVITVELYPASKRATAFGFLNAMCKLAAILGSSIFASFIGITKVIPILLSFAALVSGGVLALKLPETREKVLM", "length": 687 }, "evidence": [ { "id": "HGNC:16874", "url": "https://alliancegenome.org/gene/HGNC:16874#orthology", "database": "AGR" }, { "id": "MGI:1927338", "url": "https://alliancegenome.org/gene/MGI:1927338#orthology", "database": "AGR" }, { "id": "RGD:619716", "url": "https://alliancegenome.org/gene/RGD:619716#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9W3W9", "url": "https://www.uniprot.org/uniprotkb/Q9W3W9" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9W3W9", "url": "https://www.uniprot.org/uniprotkb/Q9W3W9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "Q9W3W9", "url": "https://www.uniprot.org/uniprotkb/Q9W3W9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "Q9W3W9", "url": "https://www.uniprot.org/uniprotkb/Q9W3W9" } ], "pmid": "" }, { "name": "centromere clustering", "id": "GO:0098653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098653", "evidence": [ { "database": "UniProtKB", "id": "Q9W3W9", "url": "https://www.uniprot.org/uniprotkb/Q9W3W9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 25, "end_pos": 27, "annotation": "n_glycosylation_sequon" }, { "start_pos": 424, "end_pos": 426, "annotation": "n_glycosylation_sequon" }, { "start_pos": 476, "end_pos": 478, "annotation": "n_glycosylation_sequon" }, { "start_pos": 48, "end_pos": 50, "annotation": "n_glycosylation_sequon" }, { "start_pos": 625, "end_pos": 627, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9W3W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W3W9" }, { "id": "PS50850", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50850" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Major facilitator superfamily (MFS) profile", "eco_id": "ECO_0000259", "start_pos": 151, "end_pos": 628, "start_aa": "Tyr", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 25, "end_pos": 27 }, { "start_pos": 424, "end_pos": 426 }, { "start_pos": 476, "end_pos": 478 }, { "start_pos": 48, "end_pos": 50 }, { "start_pos": 625, "end_pos": 627 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9W409-1", "uniprot_ac": "Q9W409", "uniprot_id": "Q9W409_DROME", "mass": { "chemical_mass": 60687.0, "monoisotopic_mass": 60687.0 }, "refseq": { "ac": "NP_572312", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572312" }, "gene_names": [ { "name": "Dmel\\CG12219", "type": "recommended", "evidence": [ { "id": "Q9W409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W409" } ] }, { "name": "BEST:LD26135", "type": "synonym", "evidence": [ { "id": "NP_572312", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572312" }, { "id": "Q9W409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W409" } ] }, { "name": "CG12219", "type": "synonym", "evidence": [ { "id": "NP_572312", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572312" }, { "id": "Q9W409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W409" } ] }, { "name": "Dmel\\CG12219", "type": "synonym", "evidence": [ { "id": "NP_572312", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572312" } ] }, { "name": "Dmel_CG12219", "type": "synonym", "evidence": [ { "id": "Q9W409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W409" } ] } ], "protein_names": [ { "name": "CG12219-PA", "type": "synonym", "evidence": [ { "id": "NP_572312", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572312" } ] }, { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "Q9W409", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W409/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_572312", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572312" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W409", "url": "https://www.uniprot.org/uniprotkb/Q9W409" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG12219", "url": "https://www.uniprot.org/uniprotkb/Q9W409", "locus": { "chromosome": "X", "start_pos": 6299054, "end_pos": 6301285, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0043796", "url": "https://www.ensemblgenomes.org/id/FBgn0043796" } ] } } ], "crossref": [ { "id": "FB:FBgn0043796", "url": "https://alliancegenome.org/gene/FB:FBgn0043796", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0043796", "url": "https://bgee.org/?page=gene&gene_id=FBgn0043796", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0043796", "url": "https://flybase.org/reports/FBgn0043796", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "31572", "url": "https://www.ncbi.nlm.nih.gov/gene/31572", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012934", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012934", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG12219", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG12219", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CPTEFRS", "url": "https://omabrowser.org/oma/group/CPTEFRS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W409", "url": "https://www.orthodb.org/?gene=Q9W409", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24388", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24388", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24388:SF54", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24388:SF54", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07776", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07776", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-3214815", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-3214815", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-9940951", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9940951", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_572312", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572312", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W409", "url": "https://www.uniprot.org/uniprotkb/Q9W409", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W409-1", "url": "https://www.uniprot.org/uniprotkb/Q9W409-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MICRLCLNALDEQSAVLLFDGAGGASAPAPDDEDDGKAMPESYLVQLISIHLYLCLSRDDAISTCICTECCSQLESFHNFWKLVELKQTTLCSQFLAIDCDVNWSEDGSETQLDAQPQLLLEPAEEPKVVTPTTANKFPCMFCEKSFKMRRYLEEHIATHTGDRPIACPYCEMAFRCRSNMYTHVKSKHTTQWLKAREERDAAKSNQNHTTPEETAPAVLVPVPAPAPALASAPASSASPGNTVNPAATATPASSATPTTNLAAAPLPSPPTVQQLPLSVIKSQPSEAMNLTITKTPPSGSRGSRNRSSRRKTHSPKKVQHTEGSDVSDEDSPQKRLKENELILANYNAVAAAVVAAASLTGNPPGQPDSLQQRLCASLLQQQHQEQLFAVMSATAAAAAAVGTSSATTTTTTTTGTMMAHPYGNHPPSETDKRPAAPLQAVIHAAPVSIICPNCGELPGQNHRCLSKPKYACDVCGKSFKMKRYLEEHFATHTGVKLHTCAFCPTEFRSKSNMYHHTKRKHKAEWERSRATRSAAKAGVQEQMQHTNPSQAQAQPGPAAAL", "length": 562, "header": "tr|Q9W409-1|Q9W409_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG12219 PE=3 SV=1 CANONICAL=Q9W409-1" }, "isoforms": [ { "isoform_ac": "Q9W409-1", "url": "https://www.uniprot.org/uniprotkb/Q9W409/entry#Q9W409-1", "sequence": { "sequence": "MICRLCLNALDEQSAVLLFDGAGGASAPAPDDEDDGKAMPESYLVQLISIHLYLCLSRDDAISTCICTECCSQLESFHNFWKLVELKQTTLCSQFLAIDCDVNWSEDGSETQLDAQPQLLLEPAEEPKVVTPTTANKFPCMFCEKSFKMRRYLEEHIATHTGDRPIACPYCEMAFRCRSNMYTHVKSKHTTQWLKAREERDAAKSNQNHTTPEETAPAVLVPVPAPAPALASAPASSASPGNTVNPAATATPASSATPTTNLAAAPLPSPPTVQQLPLSVIKSQPSEAMNLTITKTPPSGSRGSRNRSSRRKTHSPKKVQHTEGSDVSDEDSPQKRLKENELILANYNAVAAAVVAAASLTGNPPGQPDSLQQRLCASLLQQQHQEQLFAVMSATAAAAAAVGTSSATTTTTTTTGTMMAHPYGNHPPSETDKRPAAPLQAVIHAAPVSIICPNCGELPGQNHRCLSKPKYACDVCGKSFKMKRYLEEHFATHTGVKLHTCAFCPTEFRSKSNMYHHTKRKHKAEWERSRATRSAAKAGVQEQMQHTNPSQAQAQPGPAAAL", "length": 562, "header": "tr|Q9W409-1|Q9W409_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG12219 PE=3 SV=1 CANONICAL=Q9W409-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 251, "start_aa": "Thr", "end_pos": 251, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr251", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W409", "url": "https://www.uniprot.org/uniprotkb/Q9W409" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W409", "url": "https://www.uniprot.org/uniprotkb/Q9W409" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W409", "url": "https://www.uniprot.org/uniprotkb/Q9W409" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W409", "url": "https://www.uniprot.org/uniprotkb/Q9W409" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W409", "url": "https://www.uniprot.org/uniprotkb/Q9W409" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W409", "url": "https://www.uniprot.org/uniprotkb/Q9W409" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W409", "url": "https://www.uniprot.org/uniprotkb/Q9W409" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W409", "url": "https://www.uniprot.org/uniprotkb/Q9W409" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W409", "url": "https://www.uniprot.org/uniprotkb/Q9W409" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W409", "url": "https://www.uniprot.org/uniprotkb/Q9W409" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W409", "url": "https://www.uniprot.org/uniprotkb/Q9W409" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], 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sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W418", "url": "https://www.uniprot.org/uniprotkb/Q9W418" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W418", "url": 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perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W418", "url": "https://www.uniprot.org/uniprotkb/Q9W418" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W418", "url": "https://www.uniprot.org/uniprotkb/Q9W418" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { 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"https://www.reactome.org/PathwayBrowser/#R-DME-901032", "resource": "Reactome", "description": "ER Quality Control Compartment (ERQC)" }, { "id": "R-DME-9010553", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9010553", "resource": "Reactome", "description": "Regulation of expression of SLITs and ROBOs" }, { "id": "R-DME-9020702", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9020702", "resource": "Reactome", "description": "Interleukin-1 signaling" }, { "id": "R-DME-9033241", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9033241", "resource": "Reactome", "description": "Peroxisomal protein import" }, { "id": "R-DME-912631", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-912631", "resource": "Reactome", "description": "Regulation of signaling by CBL" }, { "id": "R-DME-917729", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-917729", "resource": "Reactome", "description": "Endosomal Sorting Complex Required For Transport (ESCRT)" }, { "id": "R-DME-917937", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-917937", "resource": "Reactome", "description": "Iron uptake and transport" }, { "id": "R-DME-937039", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-937039", "resource": "Reactome", "description": "IRAK1 recruits IKK complex" }, { "id": "R-DME-937042", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-937042", "resource": "Reactome", "description": "IRAK2 mediated activation of TAK1 complex" }, { "id": "R-DME-937072", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-937072", "resource": "Reactome", "description": "TRAF6-mediated induction of TAK1 complex within TLR4 complex" }, { "id": "R-DME-9646399", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9646399", "resource": "Reactome", "description": "Aggrephagy" }, { "id": "R-DME-9648002", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9648002", "resource": "Reactome", "description": "RAS processing" }, { "id": "R-DME-9664873", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9664873", "resource": "Reactome", "description": "Pexophagy" }, { "id": "R-DME-975144", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-975144", "resource": "Reactome", "description": "IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation" }, { "id": "R-DME-975163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-975163", "resource": "Reactome", "description": "IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation" }, { "id": "R-DME-9755511", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9755511", "resource": "Reactome", "description": "KEAP1-NFE2L2 pathway" }, { "id": "R-DME-975956", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-975956", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" }, { "id": "R-DME-975957", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-975957", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" }, { "id": "R-DME-9762114", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9762114", "resource": "Reactome", "description": "GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2" }, { "id": "R-DME-9770562", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9770562", "resource": "Reactome", "description": "mRNA Polyadenylation" }, { "id": "R-DME-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" }, { "id": "R-DME-9861718", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9861718", "resource": "Reactome", "description": "Regulation of pyruvate metabolism" }, { "id": "R-DME-9929491", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9929491", "resource": "Reactome", "description": "SPOP-mediated proteasomal degradation of PD-L1(CD274)" }, { "id": "R-DME-9932298", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9932298", "resource": "Reactome", "description": "Degradation of CRY and PER proteins" }, { "id": "R-DME-9954709", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9954709", "resource": "Reactome", "description": "Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide" }, { "id": "R-DME-9954714", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9954714", "resource": "Reactome", "description": "PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA" }, { "id": "R-DME-9954716", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9954716", "resource": "Reactome", "description": "ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA" }, { "id": "R-DME-9958825", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9958825", "resource": "Reactome", "description": "Activation of STAT3 by cadherin engagement" } ], "orthologs": [ { "uniprot_canonical_ac": "F1QHN6-1", "protein_name": "Polyubiquitin-C", "gene_name": "ubc", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGK", "length": 533 }, "evidence": [ { "id": "MGI:98889", "url": "https://alliancegenome.org/gene/MGI:98889#orthology", "database": "AGR" }, { "id": "HGNC:12468", "url": "https://alliancegenome.org/gene/HGNC:12468#orthology", "database": "AGR" }, { "id": "Q9W418", "url": "https://omabrowser.org/oma/group/Q9W418/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGV", "length": 685 }, "evidence": [ { "id": "MGI:98889", "url": "https://alliancegenome.org/gene/MGI:98889#orthology", "database": "AGR" }, { "id": "HGNC:12468", "url": "https://alliancegenome.org/gene/HGNC:12468#orthology", "database": "AGR" }, { "id": "FB:FBgn0086558", "url": "https://alliancegenome.org/gene/FB:FBgn0086558#orthology", "database": "AGR" }, { "id": "RGD:621244", "url": "https://alliancegenome.org/gene/RGD:621244#orthology", "database": "AGR" }, { "id": "SGD:S000003962", "url": "https://alliancegenome.org/gene/SGD:S000003962#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0CG50-1", "protein_name": "Polyubiquitin-C", "gene_name": "Ubc", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLDVEPSVTTKKVKQEDRRTFLTTVSKKSPPCACSWV", "length": 734 }, "evidence": [ { "id": "MGI:98889", "url": "https://alliancegenome.org/gene/MGI:98889#orthology", "database": "AGR" }, { "id": "HGNC:12468", "url": "https://alliancegenome.org/gene/HGNC:12468#orthology", "database": "AGR" }, { "id": "FB:FBgn0086558", "url": "https://alliancegenome.org/gene/FB:FBgn0086558#orthology", "database": "AGR" }, { "id": "RGD:621244", "url": "https://alliancegenome.org/gene/RGD:621244#orthology", "database": "AGR" }, { "id": "SGD:S000003962", "url": "https://alliancegenome.org/gene/SGD:S000003962#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0CG51-1", "protein_name": "Polyubiquitin-B", "gene_name": "Ubb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGY", "length": 305 }, "evidence": [ { "id": "SGD:S000003962", "url": "https://alliancegenome.org/gene/SGD:S000003962#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0CG63-1", "protein_name": "Polyubiquitin", "gene_name": "UBI4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGN", "length": 381 }, "evidence": [ { "id": "MGI:98889", "url": "https://alliancegenome.org/gene/MGI:98889#orthology", "database": "AGR" }, { "id": "HGNC:12468", "url": "https://alliancegenome.org/gene/HGNC:12468#orthology", "database": "AGR" }, { "id": "FB:FBgn0086558", "url": "https://alliancegenome.org/gene/FB:FBgn0086558#orthology", "database": "AGR" }, { "id": "RGD:621244", "url": "https://alliancegenome.org/gene/RGD:621244#orthology", "database": "AGR" }, { "id": "SGD:S000003962", "url": "https://alliancegenome.org/gene/SGD:S000003962#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P0CG69-1", "protein_name": "Polyubiquitin", "gene_name": "Ubi-p63E", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGIQA", "length": 763 }, "evidence": [ { "id": "MGI:98889", "url": "https://alliancegenome.org/gene/MGI:98889#orthology", "database": "AGR" }, { "id": "HGNC:12468", "url": "https://alliancegenome.org/gene/HGNC:12468#orthology", "database": "AGR" }, { "id": "RGD:621244", "url": "https://alliancegenome.org/gene/RGD:621244#orthology", "database": "AGR" }, { "id": "SGD:S000003962", "url": "https://alliancegenome.org/gene/SGD:S000003962#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P0CG79-1", "protein_name": "Polyubiquitin-G", "gene_name": "ubqG", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MQIFVKTLTGKTITLEVEGSDNIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEGSDNIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEGSDNIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEGSDNIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEGSDNIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGL", "length": 381 }, "evidence": [ { "id": "Q9W418", "url": "https://omabrowser.org/oma/group/Q9W418/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q63429-1", "protein_name": "Polyubiquitin-C", "gene_name": "Ubc", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSVNTKKVKQEDTRTFLTTVSRKSPSCACSWV", "length": 810 }, "evidence": [ { "id": "MGI:98889", "url": "https://alliancegenome.org/gene/MGI:98889#orthology", "database": "AGR" }, { "id": "HGNC:12468", "url": 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"pmid": "" }, { "name": "polytene chromosome band", "id": "GO:0005704", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005704", "evidence": [ { "database": "UniProtKB", "id": "Q9W418", "url": "https://www.uniprot.org/uniprotkb/Q9W418" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q9W418", "url": "https://www.uniprot.org/uniprotkb/Q9W418" } ], "pmid": "" }, { "name": "modification-dependent protein catabolic process", "id": "GO:0019941", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019941", "evidence": [ { "database": "UniProtKB", "id": "Q9W418", "url": "https://www.uniprot.org/uniprotkb/Q9W418" } ], "pmid": "" }, { "name": "programmed cell death involved in cell development", "id": "GO:0010623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010623", "evidence": [ { "database": "UniProtKB", 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"categories": [ "Enzyme and Pathway" ] }, { "id": "Q9W423", "url": "https://www.uniprot.org/uniprotkb/Q9W423", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W423-1", "url": "https://www.uniprot.org/uniprotkb/Q9W423-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDILNEFSNVFWSTHIWLPPNTTWADIAPGSRPDVVHANYKDLIWPIPFAAVVMLVRYTLERFWISPVGKSLGIRSSRPKKAANVPILEKTYAKSTRLDKKKLVPLSKQTDMSEREIERWWRLRRAQDKPSTLVKFCENTWRCIYYLYSFIFGVIVLWDKPWFWDVKSCWYGYPHQSISNDIWWYYMISMSFYWSLTGTQFFDVKRKDFWQMFIHHMVTLLLMSLSWVCNLHRVGSLVLVVHDCADIFLEAAKLTKYAKYQKLCDAIFAIFTVVWIVTRLGFYPRIIYSSSVEAPRILPMFPAYYIFNSLLLMLLVLHVIWTYMILKIVVDSLQKGLMSGDIRSSDSEDLTDSSGNARLTNGSARSKNKSISSAPSDKGSAGGAGSRAGARVATTERREE", "length": 400, "header": "tr|Q9W423-1|Q9W423_DROME Isoform 1 of Schlank, isoform A OS=Drosophila melanogaster OX=7227 GN=schlank PE=1 SV=2 CANONICAL=Q9W423-1" }, "isoforms": [ { "isoform_ac": "Q9W423-1", "url": "https://www.uniprot.org/uniprotkb/Q9W423/entry#Q9W423-1", "sequence": { "sequence": "MDILNEFSNVFWSTHIWLPPNTTWADIAPGSRPDVVHANYKDLIWPIPFAAVVMLVRYTLERFWISPVGKSLGIRSSRPKKAANVPILEKTYAKSTRLDKKKLVPLSKQTDMSEREIERWWRLRRAQDKPSTLVKFCENTWRCIYYLYSFIFGVIVLWDKPWFWDVKSCWYGYPHQSISNDIWWYYMISMSFYWSLTGTQFFDVKRKDFWQMFIHHMVTLLLMSLSWVCNLHRVGSLVLVVHDCADIFLEAAKLTKYAKYQKLCDAIFAIFTVVWIVTRLGFYPRIIYSSSVEAPRILPMFPAYYIFNSLLLMLLVLHVIWTYMILKIVVDSLQKGLMSGDIRSSDSEDLTDSSGNARLTNGSARSKNKSISSAPSDKGSAGGAGSRAGARVATTERREE", "length": 400, "header": "tr|Q9W423-1|Q9W423_DROME Isoform 1 of Schlank, isoform A OS=Drosophila melanogaster OX=7227 GN=schlank PE=1 SV=2 CANONICAL=Q9W423-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W423", "url": "https://www.uniprot.org/uniprotkb/Q9W423" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W423", "url": "https://www.uniprot.org/uniprotkb/Q9W423" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W423", "url": "https://www.uniprot.org/uniprotkb/Q9W423" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W423", "url": "https://www.uniprot.org/uniprotkb/Q9W423" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W423", "url": "https://www.uniprot.org/uniprotkb/Q9W423" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W423", "url": "https://www.uniprot.org/uniprotkb/Q9W423" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W423", "url": "https://www.uniprot.org/uniprotkb/Q9W423" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W423", "url": "https://www.uniprot.org/uniprotkb/Q9W423" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W423", "url": "https://www.uniprot.org/uniprotkb/Q9W423" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W423", "url": "https://www.uniprot.org/uniprotkb/Q9W423" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W423", "url": "https://www.uniprot.org/uniprotkb/Q9W423" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG3576", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3576", "resource": "KEGG Pathway" }, { "id": "R-DME-1660661", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1660661", "resource": "Reactome", "description": "Sphingolipid de novo biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JXZ1-1", "protein_name": "Ceramide synthase 5", "gene_name": "Cers5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATAAAEALGLLWGWLWSGRFWLPQNVSWADLEGPGDGYGYPRARHVLSVFPLAAGLFSVRMLFERFIAKPCALRIGIEDSAVYQVESNVTLEKVFTSISKYPDEKRLKGLSKQLDWDVRKIQCWFRHRRNQDKPPTLTKFCESMWRFTFYFCIFCYGVRFLWSMPWLWDTRQCWYNYPYQPLSRELYYYYLTQLAFYWSLVFSQFIDVKRKDFLMMFMHHLIAVTLISFSYINNMVRVGAIILCLHDSADSLLEAAKLANYARQERLCNTLFVIFGAAFMVTRLGIFPLWILNTTLFESWEIIGPFPSWWLFNGLLLILQMLHVIWSYLIARTAFKALVRGKVSKDDRSDVESSSEEDETTHTNNLSGSSSSNGANCMNGRMGGSHLAEEQGTCKAAGNLHFGASPRIHSCD", "length": 413 }, "evidence": [ { "id": "FB:FBgn0040918", "url": "https://alliancegenome.org/gene/FB:FBgn0040918#orthology", "database": "AGR" }, { "id": "RGD:1311597", "url": "https://alliancegenome.org/gene/RGD:1311597#orthology", "database": "AGR" }, { "id": "MGI:1919199", "url": "https://alliancegenome.org/gene/MGI:1919199#orthology", "database": "AGR" }, { "id": "HGNC:23749", "url": "https://alliancegenome.org/gene/HGNC:23749#orthology", "database": "AGR" }, { "id": "SGD:S000001491", "url": "https://alliancegenome.org/gene/SGD:S000001491#orthology", "database": "AGR" }, { "id": "SGD:S000000995", "url": "https://alliancegenome.org/gene/SGD:S000000995#orthology", "database": "AGR" }, { "id": "Q9W423", "url": "https://omabrowser.org/oma/group/Q9W423/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A742-1", "protein_name": "Ceramide synthase 6", "gene_name": "Cers6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFIAKPCAVALNIQANGPQIAQPNAILEKVFTAITKHPDEKRLEGLSKQLDWDVRSIQRWFRQRRNQEKPSTLTRFCESMWRFSFYLYVFSYGVRFLKQTPWLWNTRHCWYNYPYQPLTADLHYYYILELSFYWSLMVSQFTDIKRKDFGIMFLHHLATIFLITFSYVNNMARVGTLVLCLHDSADALLEAAKMANYAKFQKMCDLLFVMFAVVFITTRLGIFPLWVLNTTLFESWEIVGPYPSWWVFNLLLLLLQGLNCFWSYLIVKIACKTVSKGKVSKDDRSDIESSSDDEDSEPPGKKLHSSTTTNGTSGTNGYLLTGPCSMDD", "length": 384 }, "evidence": [ { "id": "MGI:2442564", "url": "https://alliancegenome.org/gene/MGI:2442564#orthology", "database": "AGR" }, { "id": "HGNC:23826", "url": "https://alliancegenome.org/gene/HGNC:23826#orthology", "database": "AGR" }, { "id": "FB:FBgn0040918", "url": "https://alliancegenome.org/gene/FB:FBgn0040918#orthology", "database": "AGR" }, { "id": "RGD:1561599", "url": "https://alliancegenome.org/gene/RGD:1561599#orthology", "database": "AGR" }, { "id": "SGD:S000000995", "url": "https://alliancegenome.org/gene/SGD:S000000995#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M2B5Y1-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "cers3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLSEWFWWDRLWLPRPVTWADLQDSEGCVYARASHLYIILPVAVLLLGLRALYERLIAVPLAQALGVKDKIRKRASHNPLLETYYRTHSKHPTQADVKGVCKKLGWSERQVERWFRQRRNQDRPGVQKKFKEASWRFAFYLCSTFGGVLALYDKPWFYDLREVWAKFPKQSLLDSQYWYYITEMSFYGSLLFSVAADVKRKDFKEQLVHHWATLTLLSFSWCANYIRIGTLVMLVHDTSDVLLESAKMFNYAGWETTCNSVFVVFALVFMVTRLIIFPFWLIHCTWVYPLDQFEPFFGYYFFNAMLMVLLFLHVFWASLILRMVKKFLFGNLKGDERSDEEEDEGSEEEYTHAYTNGSGNGLSNGH", "length": 366 }, "evidence": [ { "id": "MGI:2681008", "url": "https://alliancegenome.org/gene/MGI:2681008#orthology", "database": "AGR" }, { "id": "HGNC:23752", "url": "https://alliancegenome.org/gene/HGNC:23752#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080220-32", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080220-32#orthology", "database": "AGR" }, { "id": "FB:FBgn0040918", "url": "https://alliancegenome.org/gene/FB:FBgn0040918#orthology", "database": "AGR" }, { "id": "RGD:1564356", "url": "https://alliancegenome.org/gene/RGD:1564356#orthology", "database": "AGR" }, { "id": "SGD:S000000995", "url": "https://alliancegenome.org/gene/SGD:S000000995#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M2BAR8-1", "protein_name": "Ceramide synthase 2", "gene_name": "cers4b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDALSRWFWKQEFWLPPGIVWEDLEEMQGSRRPMPRDLLLALPLALAFIMLRYAFERRVAFPLSRVLGVKDPVRLKVTPSPSLEAFYTKNSRQPTQIEISGLVKQCGLTHRQVETWFRNRRNLDRPSNTTKFCEACWRFAFYLVAFTAGLLSLINTAWFWDQRECWRGFPRQPLQELHYWYYMLELSFYWSLLLCVSVDVKRKDFKEQIIHHFATIFLLGFSYCSNYIRIGTLVMLVHDASDFLLESAKMFNYAGWKKTCDSLFVIFAAVFLVTRLLVFPSKIIYTTLVLSMEVFEPFLGYYFFNALLLVLQALHIYWAYLILRMVYKFLFLGKLDKDERSDVETEPEEEEEEEKEEEEEEQRSWRKRKVVLDSRRAMLSSSCVLNNLTQQKADAQRRPKAR", "length": 402 }, "evidence": [ { "id": "RGD:1309303", "url": "https://alliancegenome.org/gene/RGD:1309303#orthology", "database": "AGR" }, { "id": "MGI:1914510", "url": "https://alliancegenome.org/gene/MGI:1914510#orthology", "database": "AGR" }, { "id": "HGNC:23747", "url": "https://alliancegenome.org/gene/HGNC:23747#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110719-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110719-2#orthology", "database": "AGR" }, { "id": "FB:FBgn0040918", "url": "https://alliancegenome.org/gene/FB:FBgn0040918#orthology", "database": "AGR" }, { "id": "SGD:S000001491", "url": "https://alliancegenome.org/gene/SGD:S000001491#orthology", "database": "AGR" }, { "id": "SGD:S000000995", "url": "https://alliancegenome.org/gene/SGD:S000000995#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TEC1-1", "protein_name": "Ceramide synthase 4a isoform X1", "gene_name": "cers4a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MCIPLINGFMQLEDNINRWLWREDFWLPPGVTWKDIAEGTSDGSRHPVPRDLLISFPLALGFIALRFVFERVVALPLSRRLGVRDRVRLHITPIPKLEAFYLQKKKTEPSQEDLQALVKLCGLSERQIQSWLRRRRIQDRPANSRKFSEASWRFGFYLIIFSAGLISLIHTPWFWDHRECWSGYPAQAVAEAQYWYYIIELSFYLSLLLCVSVDIKRKDFQEQIIHHIATIFLIAFSYCANYVRVGTLVMLVHDSSDFLLESAKMFNYAGWRKTCDALFVVFAAVFLVTRLIVFPFRIVYTAVVDSLDVFSPYPGYYFFNGLLLVLQALHIFWAWLILRMVHKFVFLGKVERDERSDDESEPDEDDEVGEEEEERSWEHKKGALNSKLASLANNCVLNNLTNQRQKMNSRTLKER", "length": 415 }, "evidence": [ { "id": "RGD:1309303", "url": "https://alliancegenome.org/gene/RGD:1309303#orthology", "database": "AGR" }, { "id": "MGI:1914510", "url": "https://alliancegenome.org/gene/MGI:1914510#orthology", "database": "AGR" }, { "id": "HGNC:23747", "url": "https://alliancegenome.org/gene/HGNC:23747#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-020808-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-020808-1#orthology", "database": "AGR" }, { "id": "FB:FBgn0040918", "url": "https://alliancegenome.org/gene/FB:FBgn0040918#orthology", "database": "AGR" }, { "id": "SGD:S000001491", "url": "https://alliancegenome.org/gene/SGD:S000001491#orthology", "database": "AGR" }, { "id": "SGD:S000000995", "url": "https://alliancegenome.org/gene/SGD:S000000995#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABK0M5E6-1", "protein_name": "Ceramide synthase 3", "gene_name": "Cers3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGASGRAMAEWPGRMAARCRWDEHSSRKVTDIREHPHANLLPLSSAQTLHSVGLPRMHHCTACPAAFEAASSQGTGKRMFYRFRKWFWSERFWLPPTIKWSDLEDHEGLVFVKASHLYITIPYALLLLVVRYFFEKFVATPLANALGIQKAQHKIKPNAILENFFQHSTSQPSHNEVYGLAKKCNLTERQVERWFRIRQKQNKPCRLQKFQESCWRFTFYFMMTVAGAVFLYDKPWAYDLWEVWYDYPRQPLLPSQYWYYVLEMSFYWSLVFSLGSDIKRKDFLANVIHHLAAISLMSFSWCANYIRSGTLVMFVHDISDIWLESAKMFSYAGWKQTCNTLFFIFAIVFFISRFIIFPFWILYCTLILPLHYLEPFFSYIFLNLQLMILQGLHIYWGYLILKMLNRCIFTQNIQDVRSDNEEEEDEEEEEEEEEEEEEEEENTKGKETEYLKNGLGTNRHLIPNGQHGR", "length": 469 }, "evidence": [ { "id": "MGI:2681008", "url": "https://alliancegenome.org/gene/MGI:2681008#orthology", "database": "AGR" }, { "id": "HGNC:23752", "url": "https://alliancegenome.org/gene/HGNC:23752#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080220-32", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080220-32#orthology", "database": "AGR" }, { "id": "FB:FBgn0040918", "url": "https://alliancegenome.org/gene/FB:FBgn0040918#orthology", "database": "AGR" }, { "id": "RGD:1564356", "url": "https://alliancegenome.org/gene/RGD:1564356#orthology", "database": "AGR" }, { "id": "SGD:S000001491", "url": "https://alliancegenome.org/gene/SGD:S000001491#orthology", "database": "AGR" }, { "id": "SGD:S000000995", "url": "https://alliancegenome.org/gene/SGD:S000000995#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AC58G368-1", "protein_name": "Ceramide synthase 3 isoform X1", "gene_name": "cers3a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLKGMSRYTIGLSYSKGQNISYKMLVIGTLGEWFWWDRLWLPGNLTWADLKDEDGLVYARPSHLYITLPYALIFLMVRYLFERLIATPLAASLGITEKTRHRVEHNTVLEQHFRTKSKNPGQADIDGLCKKCGWSSRQVERWFRRRRNQDRPGVLKKFREASWRMIFYLLAFIGGIIALYDKPWFYNVPEVWSDYPKQSMLDSQYWYYTVEMSFYLSLVLRITFDVKRKDFKEQIIHHWATLTLLAFSWCGNYIRVGTLVLLIHDSSDILLESAKIFNYAKWFKTCNGIFVVFAAVFIVTRLIIFPFWIIHCTWVYPPLYYPPFFGYYFFNFMLIVLLMLHIFWAYLILRMVKMFLFGSLTKDERSDNEEDEEDDGETSMTEDNDEHVKVTNGCRGGGRANHH", "length": 403 }, "evidence": [ { "id": "MGI:2681008", "url": "https://alliancegenome.org/gene/MGI:2681008#orthology", "database": "AGR" }, { "id": "HGNC:23752", "url": "https://alliancegenome.org/gene/HGNC:23752#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZU86-1", "protein_name": "Ceramide synthase 4", "gene_name": "Cers4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLFSLNEWLWQETYWLPPNVTWAQLEDRDGLVFAHPHHVLAALPIALVLVAMRIIFERFVALPLSRWMGVQDPIRRKIKPNPVLEKYFLRMKQRPVETQMVLLASQCGLTLRQIQRWFRRRRNQDRPCLSKKFCEASWRFVFYLCSFVGGTSILYHESWLWTPALCWENYPHQTLNLALSWWYLLELGFYISLLITLPFDIKRKDFKEQVAHHFVTVGLIVFSYSVNLLRIGSVVLLLHDCSDYLLEGCKMLNYAHFQRGCDTLFIIFSLVFFYTRLVFFPTEVIYTAVFDSIKNSGPFFGYYFFIVLLGMLQILHVYWFCLILRMICSFLRKGQMREDIRSDVEESDSSDDEAVSEGPQLKNGMARGSRAAITNGPRSRAAACLTNGHTRAT", "length": 393 }, "evidence": [ { "id": "RGD:1309303", "url": "https://alliancegenome.org/gene/RGD:1309303#orthology", "database": "AGR" }, { "id": "MGI:1914510", "url": "https://alliancegenome.org/gene/MGI:1914510#orthology", "database": "AGR" }, { "id": "HGNC:23747", "url": "https://alliancegenome.org/gene/HGNC:23747#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110719-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110719-2#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-020808-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-020808-1#orthology", "database": "AGR" }, { "id": "FB:FBgn0040918", "url": "https://alliancegenome.org/gene/FB:FBgn0040918#orthology", "database": "AGR" }, { "id": "SGD:S000001491", "url": "https://alliancegenome.org/gene/SGD:S000001491#orthology", "database": "AGR" }, { "id": "SGD:S000000995", "url": "https://alliancegenome.org/gene/SGD:S000000995#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7F9X7-1", "protein_name": "Ceramide synthase 2", "gene_name": "cers2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLAGLSELFWQERLWFPEGLGWADLEDRDGRVYAKARDLWVALPIAVLFLLIRQLFEKYVATPLASLLGLKETVRRRVAHNPALESYYCNTSKNPTQSSVEKLSKQTGWTERQVQRWFRRRRNQDRPNLLKKFCEASWRFAFYLLAFIGGLAALIDKPWLYDLEEMWKGFPTLTLLPSQYWYYMLELAFYTSLLFSVASDVKRKDFKEQIIHHVATILLISFSWCVNYIRAGTLIMFMHDSADYLLESAKMFNYARWKNACNYIFILFAAIFIVTRLIIFPFRIMYCTWVYPVTLYPPFFGYYFFNGLLMVLLCLHMFWAALIIRLAFRFLSSNSSVEDERSDRDETDESEEEEELKNGEIKKKNGAAQNGHATYNNNHSKTE", "length": 383 }, "evidence": [ { "id": "MGI:1924143", "url": "https://alliancegenome.org/gene/MGI:1924143#orthology", "database": "AGR" }, { "id": "HGNC:14076", "url": "https://alliancegenome.org/gene/HGNC:14076#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110408-40", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110408-40#orthology", "database": "AGR" }, { "id": "FB:FBgn0040918", "url": "https://alliancegenome.org/gene/FB:FBgn0040918#orthology", "database": "AGR" }, { "id": "RGD:1310059", "url": "https://alliancegenome.org/gene/RGD:1310059#orthology", "database": "AGR" }, { "id": "SGD:S000000995", "url": "https://alliancegenome.org/gene/SGD:S000000995#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QPF3-1", "protein_name": "Ceramide synthase 6", "gene_name": "cers6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAGILAWFWNERFWLPHNVTWADLKNTDDSTFPQAEDLYLACPLAFCMFMIRLVFERFIARPCALGLKIQANGPQKAQPNAILEKVFTAITKHPDEKRLEGLSKQLDWDVRTIQRWFRQRRNQEKPSTLARFCESMWRFSFYLYIFTYGVRFLKKSPWLWNTRECWYNYPYQPLTVDLHYYYILELSFYLSLLFSQFTDIRRKDFVLMFVHHVSTISLLSFSYVNNMARVGTLVLCLHDAADVLLEAAKMANYVKCQRLCPLLFVMFALVFMGSRLALYPVWILNTTVFESWEIIGPYPSWWLFNGLLVLLQALHTFWSYLIVRIACRAISRGKAGKWNPLHVSKDDRSDIESSSDEDELHPPLQKHHTNGTNGAHGTNGYLSSSLCPDEH", "length": 391 }, "evidence": [ { "id": "MGI:2442564", "url": "https://alliancegenome.org/gene/MGI:2442564#orthology", "database": "AGR" }, { "id": "HGNC:23826", "url": "https://alliancegenome.org/gene/HGNC:23826#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3V8V4-1", "protein_name": "Ceramide synthase 2", "gene_name": "Cers2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLQTLYDYFWWERLWLPVNLTWADLEDKDGRVYAKASDLYITLPLALLFLIIRYFFELYVATPLAALLNVKEKTRLRAPPNATLEHFYLTVGKQPKQVEVDLLSRQSGLSGRQVERWFRRRRNQDRPSLLKKFREASWRFTYYLIAFVAGMAVTVDKPWFYDLRKVWEGYPIQSIIPSQYWYYMIELAFYWSLLFSIASDVKRKDFKEQIIHHVATIILLCFSWFANYVRAGTLIMALHDSSDYLLESAKMFNYAGWKNTCNNLFIVFAVVFIITRLVIMPFWILHCTMIYPLEFYPAFFGYYFFNSMMVVLQMLHVFWAYFIVRMAHKFITGKLVEDERSDREETESSEGEEAAAGAGAKSRLLANGHPILNNNHPKND", "length": 380 }, "evidence": [ { "id": "MGI:1924143", "url": "https://alliancegenome.org/gene/MGI:1924143#orthology", "database": "AGR" }, { "id": "HGNC:14076", "url": "https://alliancegenome.org/gene/HGNC:14076#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110408-40", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110408-40#orthology", "database": "AGR" }, { "id": "FB:FBgn0040918", "url": "https://alliancegenome.org/gene/FB:FBgn0040918#orthology", "database": "AGR" }, { "id": "RGD:1310059", "url": "https://alliancegenome.org/gene/RGD:1310059#orthology", "database": "AGR" }, { "id": "SGD:S000000995", "url": "https://alliancegenome.org/gene/SGD:S000000995#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3LQ11-1", "protein_name": "sphingosine N-acyltransferase", "gene_name": "CERS5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATAAAGALGLLWGWLWSERFWLPQNVSWADLEGPGNGYGYPRARHILSVFPLAAGVFSVRLLFERFIAKPSALHIGIQDSCPYQVQPNAILEKVFISITKYPDEKRLEGLSKQLDWDVRKIQCWFRHRRNQDKPPTLTKFCESMWRFTFYLCIFCYGIRFLWSSPWFWDTRQCWHSYPYQPLTSGLYYYYIMELAFYWSLMFSQFTDIKRKDFLIMFVHHLATIALITFSYINNMVRVGTLVMCLHDASDFLLEAAKLANYAKYQRLCDTLFVVFSAVFVVTRLGIYPFWILNTTLFESWEMIGPYPSWWLFNGLLLILQVLHVIWSYLIARIAFKALIRGKVSKDDRSDVESSSEEEDVTTSTKSSCGSSSSNGANRVNGHMGGSYWAEE", "length": 392 }, "evidence": [ { "id": "Q9W423", "url": "https://omabrowser.org/oma/group/Q9W423/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P27544-1", "protein_name": "Ceramide synthase 1", "gene_name": "CERS1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAGPAAGPTGPEPMPSYAQLVQRGWGSALAAARGCTDCGWGLARRGLAEHAHLAPPELLLLALGALGWTALRSAATARLFRPLAKRCCLQPRDAAKMPESAWKFLFYLGSWSYSAYLLFGTDYPFFHDPPSVFYDWTPGMAVPRDIAAAYLLQGSFYGHSIYATLYMDTWRKDSVVMLLHHVVTLILIVSSYAFRYHNVGILVLFLHDISDVQLEFTKLNIYFKSRGGSYHRLHALAADLGCLSFGFSWFWFRLYWFPLKVLYATSHCSLRTVPDIPFYFFFNALLLLLTLMNLYWFLYIVAFAAKVLTGQVHELKDLREYDTAEAQSLKPSKAEKPLRNGLVKDKRF", "length": 350 }, "evidence": [ { "id": "SGD:S000001491", "url": "https://alliancegenome.org/gene/SGD:S000001491#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P27545-1", "protein_name": "Ceramide synthase 1", "gene_name": "Cers1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAAATPRLEAPEPMPSYAQMLQRSWASALAAAQGCGDCGWGLARRGLAEHAHLAAPELLLAVLCALGWTALRWAATTHIFRPLAKRCRLQPRDAARLPESAWKLLFYLACWSYCAYLLLGTSYPFFHDPPSVFYDWRSGMAVPWDIAVAYLLQGSFYCHSIYATVYMDSWRKDSVVMLVHHVVTLLLIASSYAFRYHNVGLLVFFLHDVSDVQLEFTKLNIYFKARGGAYHRLHGLVANLGCLSFCFCWFWFRLYWFPLKVLYATCHCSLQSVPDIPYYFFFNILLLLLMVMNIYWFLYIVAFAAKVLTGQMRELEDLREYDTLEAQTAKPCKAEKPLRNGLVKDKLF", "length": 350 }, "evidence": [ { "id": "SGD:S000001491", "url": "https://alliancegenome.org/gene/SGD:S000001491#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P28496-1", "protein_name": "Ceramide synthase LAC1", "gene_name": "LAC1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSTIKPSPSNNNLKVRSRPRRKSSIGKIDLGDTVPSLGTMFETKESKTAAKRRMQRLSEATKNDSDLVKKIWFSFREISYRHAWIAPLMILIAVYSAYFTSGNTTKTNVLHRFVAVSYQIGDTNAYGKGINDLCFVFYYMIFFTFLREFLMDVVIRPFAIRLHVTSKHRIKRIMEQMYAIFYTGVSGPFGIYCMYHSDLWFFNTKAMYRTYPDFTNPFLFKVFYLGQAAFWAQQACILVLQLEKPRKDHNELTFHHIVTLLLIWSSYVFHFTKMGLPIYITMDVSDFLLSFSKTLNYLDSGLAFFSFAIFVVAWIYLRHYINLKILWSVLTQFRTEGNYVLNFATQQYKCWISLPIVFVLIGALQLVNLYWLFLIFRVLYRILWRGILKDDRSDSESDEESDESSTTPTDSTPTKKDI", "length": 418 }, "evidence": [ { "id": "RGD:1309303", "url": "https://alliancegenome.org/gene/RGD:1309303#orthology", "database": "AGR" }, { "id": "MGI:1914510", "url": "https://alliancegenome.org/gene/MGI:1914510#orthology", "database": "AGR" }, { "id": "MGI:1924143", "url": "https://alliancegenome.org/gene/MGI:1924143#orthology", "database": "AGR" }, { "id": "MGI:2681008", "url": "https://alliancegenome.org/gene/MGI:2681008#orthology", "database": "AGR" }, { "id": "HGNC:23826", "url": "https://alliancegenome.org/gene/HGNC:23826#orthology", "database": "AGR" }, { "id": "HGNC:14076", "url": "https://alliancegenome.org/gene/HGNC:14076#orthology", "database": "AGR" }, { "id": "HGNC:23747", "url": "https://alliancegenome.org/gene/HGNC:23747#orthology", "database": "AGR" }, { "id": "HGNC:23752", "url": "https://alliancegenome.org/gene/HGNC:23752#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110719-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110719-2#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-020808-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-020808-1#orthology", "database": "AGR" }, { "id": "FB:FBgn0040918", "url": "https://alliancegenome.org/gene/FB:FBgn0040918#orthology", "database": "AGR" }, { "id": "RGD:1311597", "url": "https://alliancegenome.org/gene/RGD:1311597#orthology", "database": "AGR" }, { "id": "RGD:1564356", "url": "https://alliancegenome.org/gene/RGD:1564356#orthology", "database": "AGR" }, { "id": "MGI:1919199", "url": "https://alliancegenome.org/gene/MGI:1919199#orthology", "database": "AGR" }, { "id": "HGNC:23749", "url": "https://alliancegenome.org/gene/HGNC:23749#orthology", "database": "AGR" }, { "id": "SGD:S000001491", "url": "https://alliancegenome.org/gene/SGD:S000001491#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P38703-1", "protein_name": "Ceramide synthase LAG1", "gene_name": "LAG1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTSATDKSIDRLVVNAKTRRRNSSVGKIDLGDTVPGFAAMPESAASKNEAKKRMKALTGDSKKDSDLLWKVWFSYREMNYRHSWLTPFFILVCVYSAYFLSGNRTESNPLHMFVAISYQVDGTDSYAKGIKDLSFVFFYMIFFTFLREFLMDVVIRPFTVYLNVTSEHRQKRMLEQMYAIFYCGVSGPFGLYIMYHSDLWLFKTKPMYRTYPVITNPFLFKIFYLGQAAFWAQQACVLVLQLEKPRKDYKELVFHHIVTLLLIWSSYVFHFTKMGLAIYITMDVSDFFLSLSKTLNYLNSVFTPFVFGLFVFFWIYLRHVVNIRILWSVLTEFRHEGNYVLNFATQQYKCWISLPIVFVLIAALQLVNLYWLFLILRILYRLIWQGIQKDERSDSDSDESAENEESKEKCE", "length": 411 }, "evidence": [ { "id": "RGD:1309303", "url": "https://alliancegenome.org/gene/RGD:1309303#orthology", "database": "AGR" }, { "id": "MGI:2442564", "url": "https://alliancegenome.org/gene/MGI:2442564#orthology", "database": "AGR" }, { "id": "MGI:1914510", "url": "https://alliancegenome.org/gene/MGI:1914510#orthology", "database": "AGR" }, { "id": "MGI:1924143", "url": "https://alliancegenome.org/gene/MGI:1924143#orthology", "database": "AGR" }, { "id": "MGI:2681008", "url": "https://alliancegenome.org/gene/MGI:2681008#orthology", "database": "AGR" }, { "id": "HGNC:23826", "url": "https://alliancegenome.org/gene/HGNC:23826#orthology", "database": "AGR" }, { "id": "HGNC:14076", "url": "https://alliancegenome.org/gene/HGNC:14076#orthology", "database": "AGR" }, { "id": "HGNC:23747", "url": "https://alliancegenome.org/gene/HGNC:23747#orthology", "database": "AGR" }, { "id": "HGNC:23752", "url": "https://alliancegenome.org/gene/HGNC:23752#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110719-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110719-2#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110408-40", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110408-40#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-020808-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-020808-1#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080220-32", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080220-32#orthology", "database": "AGR" }, { "id": "FB:FBgn0040918", "url": "https://alliancegenome.org/gene/FB:FBgn0040918#orthology", "database": "AGR" }, { "id": "RGD:1311597", "url": "https://alliancegenome.org/gene/RGD:1311597#orthology", "database": "AGR" }, { "id": "RGD:1310059", "url": "https://alliancegenome.org/gene/RGD:1310059#orthology", "database": "AGR" }, { "id": "RGD:1561599", "url": "https://alliancegenome.org/gene/RGD:1561599#orthology", "database": "AGR" }, { "id": "RGD:1564356", "url": "https://alliancegenome.org/gene/RGD:1564356#orthology", "database": "AGR" }, { "id": "SGD:S000000995", "url": "https://alliancegenome.org/gene/SGD:S000000995#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q1A3B0-1", "protein_name": "Ceramide synthase 3", "gene_name": "Cers3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQTFRKWFWSERYWLPPTIKWSDLEDHDGLVFVKASHLYITIPYAFLLMVVRYFFEKFVATPLANALGIKKTQHKIKPNAILENFFKHSTSKPSHTDIYGLAKKCNLTERQVERWLRIRQKQNKPCRLQKFQESCWRFTFYLLITMAGAVFLYDKPWAYDLWEVWNDYPRQPLLPSQYWYYILEMSFYWSLVFSLSTDIKRKDFLAHVIHHLAAISLMSFSWCANYIRSGTLVMFIHDISDIWLESAKMFSYAGWKQTCNTLFFIFTVVFFISRFIIFPFWILYCTLILPLHYLEPFFSYIFLNLQLMILQGLHVYWGYFILKMLNRCIFTQNVQDVRSDNEEEEEEEEEEEAESTKGKETEYLKNGLGTNRHLIANGQHGR", "length": 383 }, "evidence": [ { "id": "MGI:2681008", "url": "https://alliancegenome.org/gene/MGI:2681008#orthology", "database": "AGR" }, { "id": "HGNC:23752", "url": "https://alliancegenome.org/gene/HGNC:23752#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080220-32", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080220-32#orthology", "database": "AGR" }, { "id": "FB:FBgn0040918", "url": "https://alliancegenome.org/gene/FB:FBgn0040918#orthology", "database": "AGR" }, { "id": "RGD:1564356", "url": "https://alliancegenome.org/gene/RGD:1564356#orthology", "database": "AGR" }, { "id": "SGD:S000001491", "url": "https://alliancegenome.org/gene/SGD:S000001491#orthology", "database": "AGR" }, { "id": "SGD:S000000995", "url": "https://alliancegenome.org/gene/SGD:S000000995#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6ZMG9-1", "protein_name": "Ceramide synthase 6", "gene_name": "CERS6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQANGPQIAPPNAILEKVFTAITKHPDEKRLEGLSKQLDWDVRSIQRWFRQRRNQEKPSTLTRFCESMWRFSFYLYVFTYGVRFLKKTPWLWNTRHCWYNYPYQPLTTDLHYYYILELSFYWSLMFSQFTDIKRKDFGIMFLHHLVSIFLITFSYVNNMARVGTLVLCLHDSADALLEAAKMANYAKFQKMCDLLFVMFAVVFITTRLGIFPLWVLNTTLFESWEIVGPYPSWWVFNLLLLLVQGLNCFWSYLIVKIACKAVSRGKVSKDDRSDIESSSDEEDSEPPGKNPHTATTTNGTSGTNGYLLTGSCSMDD", "length": 384 }, "evidence": [ { "id": "MGI:2442564", "url": "https://alliancegenome.org/gene/MGI:2442564#orthology", "database": "AGR" }, { "id": "HGNC:23826", "url": "https://alliancegenome.org/gene/HGNC:23826#orthology", "database": "AGR" }, { "id": "FB:FBgn0040918", "url": "https://alliancegenome.org/gene/FB:FBgn0040918#orthology", "database": "AGR" }, { "id": "RGD:1561599", "url": "https://alliancegenome.org/gene/RGD:1561599#orthology", "database": "AGR" }, { "id": "SGD:S000001491", "url": "https://alliancegenome.org/gene/SGD:S000001491#orthology", "database": "AGR" }, { "id": "SGD:S000000995", "url": "https://alliancegenome.org/gene/SGD:S000000995#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8C172-1", "protein_name": "Ceramide synthase 6", "gene_name": "Cers6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFIAKPCAIALNIQANGPQTAQPNAILEKVFTAITKHPDEKRLEGLSKQLDWDVRSIQRWFRQRRNQEKPSTLTRFCESMWRFSFYLYVFSYGVRFLKQTPWLWNTRHCWYNYPYQPLTADLHYYYILELSFYWSLMVSQFTDIKRKDFGIMFLHHLATIFLITFSYVNNMARVGTLVLCLHDSADALLEAAKMANYAKFQKMCDLLFVMFAVVFITTRLGIFPLWVLNTTLFESWEIVGPYPSWWVFNLLLLLLQGLNCFWSYLIVKIACKTVSKGKVSKDDRSDIESSSDDEDSEPPGKKPHSSTTTNGTSGTNGYLLTGPCSVDD", "length": 384 }, "evidence": [ { "id": "MGI:2442564", "url": "https://alliancegenome.org/gene/MGI:2442564#orthology", "database": "AGR" }, { "id": "HGNC:23826", "url": "https://alliancegenome.org/gene/HGNC:23826#orthology", "database": "AGR" }, { "id": "FB:FBgn0040918", "url": "https://alliancegenome.org/gene/FB:FBgn0040918#orthology", "database": "AGR" }, { "id": "RGD:1561599", "url": "https://alliancegenome.org/gene/RGD:1561599#orthology", "database": "AGR" }, { "id": "SGD:S000000995", "url": "https://alliancegenome.org/gene/SGD:S000000995#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IU89-1", "protein_name": "Ceramide synthase 3", "gene_name": "CERS3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFWTFKEWFWLERFWLPPTIKWSDLEDHDGLVFVKPSHLYVTIPYAFLLLIIRRVFEKFVASPLAKSFGIKETVRKVTPNTVLENFFKHSTRQPLQTDIYGLAKKCNLTERQVERWFRSRRNQERPSRLKKFQEACWRFAFYLMITVAGIAFLYDKPWLYDLWEVWNGYPKQPLLPSQYWYYILEMSFYWSLLFRLGFDVKRKDFLAHIIHHLAAISLMSFSWCANYIRSGTLVMIVHDVADIWLESAKMFSYAGWTQTCNTLFFIFSTIFFISRLIVFPFWILYCTLILPMYHLEPFFSYIFLNLQLMILQVLHLYWGYYILKMLNRCIFMKSIQDVRSDDEDYEEEEEEEEEEATKGKEMDCLKNGLRAERHLIPNGQHGH", "length": 383 }, "evidence": [ { "id": "MGI:2681008", "url": "https://alliancegenome.org/gene/MGI:2681008#orthology", "database": "AGR" }, { "id": "HGNC:23752", "url": "https://alliancegenome.org/gene/HGNC:23752#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080220-32", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080220-32#orthology", "database": "AGR" }, { "id": "FB:FBgn0040918", "url": "https://alliancegenome.org/gene/FB:FBgn0040918#orthology", "database": "AGR" }, { "id": "RGD:1564356", "url": "https://alliancegenome.org/gene/RGD:1564356#orthology", "database": "AGR" }, { "id": "SGD:S000001491", "url": "https://alliancegenome.org/gene/SGD:S000001491#orthology", "database": "AGR" }, { "id": "SGD:S000000995", "url": "https://alliancegenome.org/gene/SGD:S000000995#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8N5B7-1", "protein_name": "Ceramide synthase 5", "gene_name": "CERS5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATAAQGPLSLLWGWLWSERFWLPENVSWADLEGPADGYGYPRGRHILSVFPLAAGIFFVRLLFERFIAKPCALCIGIEDSGPYQAQPNAILEKVFISITKYPDKKRLEGLSKQLDWNVRKIQCWFRHRRNQDKPPTLTKFCESMWRFTFYLCIFCYGIRFLWSSPWFWDIRQCWHNYPFQPLSSGLYHYYIMELAFYWSLMFSQFTDIKRKDFLIMFVHHLVTIGLISFSYINNMVRVGTLIMCLHDVSDFLLEAAKLANYAKYQRLCDTLFVIFSAVFMVTRLGIYPFWILNTTLFESWEIIGPYASWWLLNGLLLTLQLLHVIWSYLIARIALKALIRGKVSKDDRSDVESSSEEEDVTTCTKSPCDSSSSNGANRVNGHMGGSYWAEE", "length": 392 }, "evidence": [ { "id": "FB:FBgn0040918", "url": "https://alliancegenome.org/gene/FB:FBgn0040918#orthology", "database": "AGR" }, { "id": "RGD:1311597", "url": "https://alliancegenome.org/gene/RGD:1311597#orthology", "database": "AGR" }, { "id": "MGI:1919199", "url": "https://alliancegenome.org/gene/MGI:1919199#orthology", "database": "AGR" }, { "id": "HGNC:23749", "url": "https://alliancegenome.org/gene/HGNC:23749#orthology", "database": "AGR" }, { "id": "SGD:S000001491", "url": "https://alliancegenome.org/gene/SGD:S000001491#orthology", "database": "AGR" }, { "id": "Q9W423", "url": "https://omabrowser.org/oma/group/Q9W423/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q924Z4-1", "protein_name": "Ceramide synthase 2", "gene_name": "Cers2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLQTLYDYFWWERLWLPVNLTWADLEDKDGRVYAKASDLYITLPLALLFLVIRYFFELYVATPLAALLNVKEKTRLRAPPNATLEHFYQTSGKQPKQVEVDLLSRQSGLSGRQVERWFRRRRNQDRPSLLKKFREASWRFTYYLIAFVAGMAVTVDKPWFYDLRKVWEGYPIQSIIPSQYWYYMIELSFYWSLLFSIASDVKRKDFKEQIIHHVATIILLCFSWFANYVRAGTLIMALHDASDYLLESAKMFNYAGWKNTCNNLFIVFAIVFIITRLVIMPFWILHCTMIYPLELYPAFFGYYFFNFMMAVLQMLHIFWAYFILRMAHKFITGKLIEDERSDREETESSEGEETAAGAGAKSRLLANGHPILNNNHPKND", "length": 380 }, "evidence": [ { "id": "MGI:1924143", "url": "https://alliancegenome.org/gene/MGI:1924143#orthology", "database": "AGR" }, { "id": "HGNC:14076", "url": "https://alliancegenome.org/gene/HGNC:14076#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110408-40", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110408-40#orthology", "database": "AGR" }, { "id": "FB:FBgn0040918", "url": "https://alliancegenome.org/gene/FB:FBgn0040918#orthology", "database": "AGR" }, { "id": "RGD:1310059", "url": "https://alliancegenome.org/gene/RGD:1310059#orthology", "database": "AGR" }, { "id": "SGD:S000001491", "url": "https://alliancegenome.org/gene/SGD:S000001491#orthology", "database": "AGR" }, { "id": "SGD:S000000995", "url": "https://alliancegenome.org/gene/SGD:S000000995#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96G23-1", "protein_name": "Ceramide synthase 2", "gene_name": "CERS2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLQTLYDYFWWERLWLPVNLTWADLEDRDGRVYAKASDLYITLPLALLFLIVRYFFELYVATPLAALLNIKEKTRLRAPPNATLEHFYLTSGKQPKQVEVELLSRQSGLSGRQVERWFRRRRNQDRPSLLKKFREASWRFTFYLIAFIAGMAVIVDKPWFYDMKKVWEGYPIQSTIPSQYWYYMIELSFYWSLLFSIASDVKRKDFKEQIIHHVATIILISFSWFANYIRAGTLIMALHDSSDYLLESAKMFNYAGWKNTCNNIFIVFAIVFIITRLVILPFWILHCTLVYPLELYPAFFGYYFFNSMMGVLQLLHIFWAYLILRMAHKFITGKLVEDERSDREETESSEGEEAAAGGGAKSRPLANGHPILNNNHRKND", "length": 380 }, "evidence": [ { "id": "MGI:1924143", "url": "https://alliancegenome.org/gene/MGI:1924143#orthology", "database": "AGR" }, { "id": "HGNC:14076", "url": "https://alliancegenome.org/gene/HGNC:14076#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110408-40", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110408-40#orthology", "database": "AGR" }, { "id": "FB:FBgn0040918", "url": "https://alliancegenome.org/gene/FB:FBgn0040918#orthology", "database": "AGR" }, { "id": "RGD:1310059", "url": "https://alliancegenome.org/gene/RGD:1310059#orthology", "database": "AGR" }, { "id": "SGD:S000001491", "url": "https://alliancegenome.org/gene/SGD:S000001491#orthology", "database": "AGR" }, { "id": "SGD:S000000995", "url": "https://alliancegenome.org/gene/SGD:S000000995#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D6J1-1", "protein_name": "Ceramide synthase 4", "gene_name": "Cers4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSFSLSEWLWQETYWLPPNVTWAELEDRDGLVFAHPHHVLAAFPVALVLVAVRIVFERFVALPLSRWMGVQDPIRRKIKPNPVLEKYFLRMKQCPEETQMVLLASQCGLTLRQTQRWFRRRRNQDRPSLSKKFCEACWRFVFYLCSFVGGTSILYHESWLWSPSLCWENYPHQTLNLSLYWWYLLELGFYLSLLITLPFDVKRKDFKEQVVHHFVAVGLIGFSYSVNLLRIGAVVLLLHDCSDYLLEGCKILNYAHFRRGCDALFIMFALVFFYTRLIFFPTQVIYTSVYDSIKNSGPFFGYYFFIVLLVMLQILHVYWFCLILRMLYSFLHKGQMTEDIRSDVEEPDSSDDEPVSEGPQLKNGMARGSRVAVTNGPRSRAAACLTNGHTRAT", "length": 393 }, "evidence": [ { "id": "RGD:1309303", "url": "https://alliancegenome.org/gene/RGD:1309303#orthology", "database": "AGR" }, { "id": "MGI:1914510", "url": "https://alliancegenome.org/gene/MGI:1914510#orthology", "database": "AGR" }, { "id": "HGNC:23747", "url": "https://alliancegenome.org/gene/HGNC:23747#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110719-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110719-2#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-020808-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-020808-1#orthology", "database": "AGR" }, { "id": "FB:FBgn0040918", "url": "https://alliancegenome.org/gene/FB:FBgn0040918#orthology", "database": "AGR" }, { "id": "SGD:S000001491", "url": "https://alliancegenome.org/gene/SGD:S000001491#orthology", "database": "AGR" }, { "id": "SGD:S000000995", "url": "https://alliancegenome.org/gene/SGD:S000000995#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9D6K9-1", "protein_name": "Ceramide synthase 5", "gene_name": "Cers5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATAAAETLGLLWGWLWSESFWLPQNVSWADLEGPGDGYGYPRAQHVLSVFPLAVCIFSVRMLFERFIAKPCALRVGIKDSPVNKVEPNDTLEKVFVSVTKYPDEKRLKGLSKQLDWSVRKIQCWFRHRRNQDKPPTLTKFCESMWRFTYYLCIFCYGIRFLWSMPWFWDTRQCWYNYPYQPLSRELYYYYITQLAFYWSLMFSQFIDVKRKDFLMMFIHHMIGIMLTTFSYVNNMVRVGALIFCLHDFADPLLEAAKMANYARRERLCTTLFVIFGAAFIVSRLAIFPLWILNTTLFESWEIIGPYPSWWLFNALLLILQVLHAIWSYLIVQTASKALSRGKVSKDDRSDVESSSEEEDETTHKNNLSGSSSSNGANCMNGYMGGSHLAEEQGTCKATGNLHFRASPHLHSCD", "length": 414 }, "evidence": [ { "id": "FB:FBgn0040918", "url": "https://alliancegenome.org/gene/FB:FBgn0040918#orthology", "database": "AGR" }, { "id": "RGD:1311597", "url": "https://alliancegenome.org/gene/RGD:1311597#orthology", "database": "AGR" }, { "id": "MGI:1919199", "url": "https://alliancegenome.org/gene/MGI:1919199#orthology", "database": "AGR" }, { "id": "HGNC:23749", "url": "https://alliancegenome.org/gene/HGNC:23749#orthology", "database": "AGR" }, { "id": "SGD:S000001491", "url": "https://alliancegenome.org/gene/SGD:S000001491#orthology", "database": "AGR" }, { "id": "Q9W423", "url": "https://omabrowser.org/oma/group/Q9W423/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9HA82-1", "protein_name": "Ceramide synthase 4", "gene_name": "CERS4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLSSFNEWFWQDRFWLPPNVTWTELEDRDGRVYPHPQDLLAALPLALVLLAMRLAFERFIGLPLSRWLGVRDQTRRQVKPNATLEKHFLTEGHRPKEPQLSLLAAQCGLTLQQTQRWFRRRRNQDRPQLTKKFCEASWRFLFYLSSFVGGLSVLYHESWLWAPVMCWDRYPNQTLKPSLYWWYLLELGFYLSLLIRLPFDVKRKDFKEQVIHHFVAVILMTFSYSANLLRIGSLVLLLHDSSDYLLEACKMVNYMQYQQVCDALFLIFSFVFFYTRLVLFPTQILYTTYYESISNRGPFFGYYFFNGLLMLLQLLHVFWSCLILRMLYSFMKKGQMEKDIRSDVEESDSSEEAAAAQEPLQLKNGAAGGPRPAPTDGPRSRVAGRLTNRHTTAT", "length": 394 }, "evidence": [ { "id": "RGD:1309303", "url": "https://alliancegenome.org/gene/RGD:1309303#orthology", "database": "AGR" }, { "id": "MGI:1914510", "url": "https://alliancegenome.org/gene/MGI:1914510#orthology", "database": "AGR" }, { "id": "HGNC:23747", "url": "https://alliancegenome.org/gene/HGNC:23747#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110719-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110719-2#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-020808-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-020808-1#orthology", "database": "AGR" }, { "id": "FB:FBgn0040918", "url": "https://alliancegenome.org/gene/FB:FBgn0040918#orthology", "database": "AGR" }, { "id": "SGD:S000001491", "url": "https://alliancegenome.org/gene/SGD:S000001491#orthology", "database": "AGR" }, { "id": "SGD:S000000995", "url": "https://alliancegenome.org/gene/SGD:S000000995#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q9W423", "url": "https://www.uniprot.org/uniprotkb/Q9W423" } ], "pmid": "" }, { "name": "sphingosine N-acyltransferase activity", "id": "GO:0050291", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050291", "evidence": [ { "database": "UniProtKB", "id": "Q9W423", "url": "https://www.uniprot.org/uniprotkb/Q9W423" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9W423", "url": "https://www.uniprot.org/uniprotkb/Q9W423" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q9W423", "url": "https://www.uniprot.org/uniprotkb/Q9W423" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9W423", "url": "https://www.uniprot.org/uniprotkb/Q9W423" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9W423", "url": "https://www.uniprot.org/uniprotkb/Q9W423" } ], "pmid": "" }, { "name": "nuclear inner membrane", "id": "GO:0005637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005637", "evidence": [ { "database": "UniProtKB", "id": "Q9W423", "url": "https://www.uniprot.org/uniprotkb/Q9W423" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "triglyceride metabolic process", "id": "GO:0006641", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006641", "evidence": [ { "database": "UniProtKB", "id": "Q9W423", "url": "https://www.uniprot.org/uniprotkb/Q9W423" } ], "pmid": "" }, { "name": "ceramide biosynthetic process", "id": "GO:0046513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046513", "evidence": [ { "database": "UniProtKB", "id": "Q9W423", "url": "https://www.uniprot.org/uniprotkb/Q9W423" } ], "pmid": "" }, { "name": "positive regulation of lipid biosynthetic process", "id": "GO:0046889", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046889", "evidence": [ { "database": "UniProtKB", "id": "Q9W423", "url": "https://www.uniprot.org/uniprotkb/Q9W423" } ], "pmid": "" }, { "name": "negative regulation of lipid catabolic process", "id": "GO:0050995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050995", "evidence": [ { "database": "UniProtKB", "id": "Q9W423", "url": "https://www.uniprot.org/uniprotkb/Q9W423" } ], "pmid": "" }, { "name": "SREBP signaling pathway", "id": "GO:0032933", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032933", "evidence": [ { "database": "UniProtKB", "id": "Q9W423", "url": "https://www.uniprot.org/uniprotkb/Q9W423" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 21, "end_pos": 23, "annotation": "n_glycosylation_sequon" }, { "start_pos": 361, "end_pos": 363, "annotation": "n_glycosylation_sequon" }, { "start_pos": 368, "end_pos": 370, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "36547", "name": "", "equation": "sphinganine + octadecanoyl-CoA = N-(octadecanoyl)-sphinganine + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9W423-1" ], "evidence": [ { "id": "36547", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/36547" } ] }, { "id": "R-DME-428185", "name": "Ceramide synthases transfer acyl-CoA onto sphingoid", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [ "R-ALL-5279323" ], "output_participant_list": [], "enzyme_list": [ "Q9W423-1" ], "evidence": [ { "id": "R-DME-428185", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-428185" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-5279323", "participant_name": "sphingoid base [cytoplasm]", "crossref": [ { "id": "35785", "database": "ChEBI", "url": "" }, { "id": "Sphingoids", "database": "AraCyc", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "Q9W423", "gene_name": "schlank", "activity": [ { "ec_number": "2.3.1.24", "activity": "a fatty acyl-CoA + sphing-4-enine = an N-acylsphing-4-enine + CoA + H(+).", "evidence": [ { "id": "Q9W423", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W423" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], 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"chemical_mass": 38248.0, "monoisotopic_mass": 38248.0 }, "refseq": { "ac": "NP_572282", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572282" }, "gene_names": [ { "name": "SP108", "type": "recommended", "evidence": [ { "id": "Q9W453", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W453" } ] }, { "name": "CG6048", "type": "synonym", "evidence": [ { "id": "NP_572282", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572282" }, { "id": "Q9W453", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W453" } ] }, { "name": "Dmel\\CG6048", "type": "synonym", "evidence": [ { "id": "NP_572282", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572282" }, { "id": "Q9W453", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W453" } ] }, { "name": "Dmel_CG6048", "type": "synonym", "evidence": [ { "id": "Q9W453", "database": "UniProtKB", "url": 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"id": "Q9W453", "url": "https://www.uniprot.org/uniprotkb/Q9W453" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "SP108", "url": "https://www.uniprot.org/uniprotkb/Q9W453", "locus": { "chromosome": "X", "start_pos": 5954046, "end_pos": 5952565, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0029827", "url": "https://www.ensemblgenomes.org/id/FBgn0029827" } ] } } ], "crossref": [ { "id": "FB:FBgn0029827", "url": "https://alliancegenome.org/gene/FB:FBgn0029827", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0029827", "url": "https://bgee.org/?page=gene&gene_id=FBgn0029827", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00190", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00190", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0029827", "url": "https://flybase.org/reports/FBgn0029827", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "31528", "url": "https://www.ncbi.nlm.nih.gov/gene/31528", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018114", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018114", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050127", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050127", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG6048", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG6048", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FVDQIIY", "url": "https://omabrowser.org/oma/group/FVDQIIY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W453", "url": "https://www.orthodb.org/?gene=Q9W453", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24264", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24264", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24264:SF65", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24264:SF65", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q9W453", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q9W453", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_572282", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572282", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W453", "url": "https://www.uniprot.org/uniprotkb/Q9W453", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W453-1", "url": "https://www.uniprot.org/uniprotkb/Q9W453-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFGLGQLLAVALLLIFLPSGLRGATTRTHLDTKAIRPRFNADPGRIINGTEASLGATRHQVGIRKALNDGYFFGTGHLCGGSLIRPGWVLTAAHCFVDQIIYDGTFVPKEEFIVVMGNLDRYNRTNTLTFTIEERIMQLDKFDLSTYDKDIALLMLNGTVPTGHPTIRPIALNRFAIPEGVVCQVTGWGNTEDGYVSDILMTVDVPMISEEHCINDSDLGHLIQPGMICAGYLEVGEKDACAGDSGGPLVCQSELAGVVSWGIQCALPRLPGVYTEVSYYYDWILQNMGENGEGSGEESGEGSGEGSGEGSGEGSGEGSGDDGSGDDEDGSGDGGGAMAAVAGSLTLLLPGILALRLMATQF", "length": 362, "header": "tr|Q9W453-1|Q9W453_DROME Isoform 1 of Peptidase S1 domain-containing protein OS=Drosophila melanogaster OX=7227 GN=SP108 PE=4 SV=1 CANONICAL=Q9W453-1" }, "isoforms": [ { "isoform_ac": "Q9W453-1", "url": "https://www.uniprot.org/uniprotkb/Q9W453/entry#Q9W453-1", "sequence": { "sequence": "MFGLGQLLAVALLLIFLPSGLRGATTRTHLDTKAIRPRFNADPGRIINGTEASLGATRHQVGIRKALNDGYFFGTGHLCGGSLIRPGWVLTAAHCFVDQIIYDGTFVPKEEFIVVMGNLDRYNRTNTLTFTIEERIMQLDKFDLSTYDKDIALLMLNGTVPTGHPTIRPIALNRFAIPEGVVCQVTGWGNTEDGYVSDILMTVDVPMISEEHCINDSDLGHLIQPGMICAGYLEVGEKDACAGDSGGPLVCQSELAGVVSWGIQCALPRLPGVYTEVSYYYDWILQNMGENGEGSGEESGEGSGEGSGEGSGEGSGEGSGDDGSGDDEDGSGDGGGAMAAVAGSLTLLLPGILALRLMATQF", "length": 362, "header": "tr|Q9W453-1|Q9W453_DROME Isoform 1 of Peptidase S1 domain-containing protein OS=Drosophila melanogaster OX=7227 GN=SP108 PE=4 SV=1 CANONICAL=Q9W453-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W453", "url": "https://www.uniprot.org/uniprotkb/Q9W453" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W453", "url": "https://www.uniprot.org/uniprotkb/Q9W453" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W453", "url": "https://www.uniprot.org/uniprotkb/Q9W453" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W453", "url": "https://www.uniprot.org/uniprotkb/Q9W453" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W453", "url": "https://www.uniprot.org/uniprotkb/Q9W453" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W453", "url": "https://www.uniprot.org/uniprotkb/Q9W453" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W453", "url": "https://www.uniprot.org/uniprotkb/Q9W453" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W453", "url": "https://www.uniprot.org/uniprotkb/Q9W453" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W453", "url": "https://www.uniprot.org/uniprotkb/Q9W453" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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CKD is classified based on cause, glomerular filtration rate (GFR) category (G2-G5), and albuminuria category (A1-A3)." }, "synonyms": [ { "id": "DOID:784", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:784", "name": "CKD", "description": "" }, { "id": "DOID:784", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:784", "name": "CRF", "description": "" }, { "id": "DOID:784", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:784", "name": "chronic kidney failure", "description": "" }, { "id": "DOID:784", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:784", "name": "chronic renal disease", "description": "" }, { "id": "DOID:784", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:784", "name": "chronic renal failure syndrome", "description": "" }, { "id": "DOID:784", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:784", "name": "renal failure - chronic", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "784", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:784" } ] }, { "disease_id": "DOID:9351", "recommended_name": { "id": "DOID:9351", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9351", "name": "diabetes mellitus", "description": "A glucose metabolism disease that is characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both." }, "synonyms": [ { "id": "DOID:9351", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9351", "name": "diabetes", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "9351", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9351" } ] }, { "disease_id": "DOID:9352", "recommended_name": { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin." }, "synonyms": [ { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "NIDDM", "description": "" }, { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "non-insulin-dependent diabetes mellitus", "description": "" }, { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "type 2 diabetes", "description": "" }, { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "type II diabetes mellitus", "description": "" }, { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "insulin resistance", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type 2 diabetes mellitus", "description": "A type of diabetes mellitus that is characterized by insulin resistance or desensitization and increased blood glucose levels. 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"https://monarchinitiative.org/disease/MONDO:0005148", "name": "adult-onset diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitis type 2", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitis type II", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent, association with", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent, late onset", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, type 2", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, type II", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes, type 2", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "insulin resistance, severe, digenic", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "non-insulin dependent diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "non-insulin dependent diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "noninsulin dependent diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "noninsulin-dependent diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type 2 diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type 2 diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type 2 diabetes mellitus non-insulin dependent", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type II diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type II diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent, 2", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "diabetes mellitus, noninsulin-dependent, 1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "diabetes mellitus, noninsulin-dependent 1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "diabetes mellitus, noninsulin-dependent, 1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "diabetes mellitus, noninsulin-dependent, type 1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "NIDDM1", "description": "" }, { "id": "MONDO:0011072", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011072", "name": "diabetes mellitus, noninsulin-dependent, 2", "description": "" }, { "id": "MONDO:0011072", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011072", "name": "NIDDM2", "description": "" }, { "id": "MONDO:0011072", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011072", "name": "diabetes mellitus, noninsulin-dependent, 2", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "diabetes mellitus, noninsulin-dependent, 3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "diabetes mellitus, noninsulin-dependent, 3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "diabetes mellitus, noninsulin-dependent, type 3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "type 2 diabetes mellitus 3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "NIDDM3", "description": "" }, { "id": "MONDO:0011955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011955", "name": "diabetes mellitus, noninsulin-dependent, 4", "description": "" }, { "id": "MONDO:0011955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011955", "name": "diabetes mellitus, noninsulin-dependent, 4", "description": "" }, { "id": "MONDO:0011955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011955", "name": "diabetes mellitus, noninsulin-dependent, type 4", "description": "" }, { "id": "MIM:125853", "resource": "MIM", "url": "https://www.omim.org/entry/125853", "name": "Type 2 diabetes mellitus", "description": "Type 2 diabetes mellitus" }, { "id": "MIM:601283", "resource": "MIM", "url": "https://www.omim.org/entry/601283", "name": "Type 2 diabetes mellitus 1", "description": "Type 2 diabetes mellitus 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ] }, { "disease_id": "DOID:9970", "recommended_name": { "id": "DOID:9970", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness." }, "synonyms": [ { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "inherited obesity", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "genetic obesity", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "genetic obesity (disease)", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "leanness, inherited, autosomal recessive", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "monogenic obesity", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "obesity, association with, Autosomal recessive", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "obesity, early-onset, susceptibility to, Autosomal recessive", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "obesity, late-onset, Autosomal recessive", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "obesity, mild, early-onset, Autosomal recessive", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "obesity, severe, Autosomal recessive", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "obesity, severe, and type II diabetes, Autosomal recessive", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "obesity, susceptibility to, Autosomal recessive", "description": "" }, { "id": "MIM:601665", "resource": "MIM", "url": "https://www.omim.org/entry/601665", "name": "Obesity", "description": "Obesity" } ], "unlinked_id_list": [], "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W475", "url": "https://www.uniprot.org/uniprotkb/Q9W475" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG3108", "url": "https://www.uniprot.org/uniprotkb/Q9W475", "locus": { "chromosome": "X", "start_pos": 5777195, "end_pos": 5781620, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0029807", "url": "https://www.ensemblgenomes.org/id/FBgn0029807" } ] } } ], "crossref": [ { "id": "FB:FBgn0029807", "url": "https://alliancegenome.org/gene/FB:FBgn0029807", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0029807", "url": "https://bgee.org/?page=gene&gene_id=FBgn0029807", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03860", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03860", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0029807", "url": "https://flybase.org/reports/FBgn0029807", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "31506", "url": "https://www.ncbi.nlm.nih.gov/gene/31506", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000834", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000834", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003146", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003146", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057246", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057246", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG3108", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3108", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ARNPGIW", "url": "https://omabrowser.org/oma/group/ARNPGIW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W475", "url": "https://www.orthodb.org/?gene=Q9W475", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11705", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11705", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11705:SF91", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11705:SF91", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00246", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00246", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02244", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02244", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-2022377", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-2022377", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_572262", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572262", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W475", "url": "https://www.uniprot.org/uniprotkb/Q9W475", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W475-1", "url": "https://www.uniprot.org/uniprotkb/Q9W475-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYNARSRGSAANEGISPKRIVTIGSLLLVLGLNQVASMSLDRLALERNELPADQQQQQQQDVLVDNMKLTSIPSADSSDMYMLVPDTVASQLEDTEHVNRNSIEADPESDPSGSSSSDMLMLESDSSPAMQLVELPSDITVAESQPETEHDTENDQQQPESIEEHVVLMKPASQEAQLEQTVDLATEAAPVPLNDELPEDEESPAATESAVEELEKESEAAMDDQVPEESEIQPEQVQPGEYQSESDGEQAETKPEIEAQPEVEAQPEAEAQPEAEPQLEVEPQPEVESQPEVESQPEVEAQPEVEPQSEVESQPEAESHSEPETQAEVEAQPEVESLPEAESQPEAESQPEREPEVEAEKISDNEVDTTEASLMETLVEGIEDGLTAAMDNLVPEELAEASDKQETELESEDQQSPVTEAIEEQAVPEIEQEKEKEPEQITLADETEQDSAQPSNEEPVEIAPEQHTEAEIAPAKIPEEGKPEEEVQVEEESKPVEESKPEEEIKQQEDAKPEEDDQNYAETQPAVTEVKPEETPADIPVEIPAEVPAEIPAEIPAEVPAEIPAESPAEIAAEVPAEIPAEIPAEIPAETPAETHAEIPADVPAQVVAEAPAETPAETPAEVPAEIPSKVQDEIQSDSTQAEPQVEKEAQQPEKETKPLESSLLTTIIPMVMPQPQVPSQPLQVQDSVLNYVNASFMQQQPSETDLPKTEEESPFNAHLRRYDGAQVWRIVVQTDKDKRMADELQSKYDGQLWKEVKQEVDYLLKPQVLAAAERHIRAANLSRIVLIDNLQRVIEKENPPAEKIAELQNRKGHRLTWQAYHRLEDIHGFIDYMAKTYPDICSTEIIGYSVEKRPLKILKISNGNARNPGIWIDGGMHAREWISPATVTYIANQLVEGWEDLPEHMRSINWYIHPVANPDGYEYSHTTDRLWRKNMRAHGRQCPGVDLNRNFGYKWGGKGTSASPCSQTYRGSKAFSEPETFYISKFISGFPRETFQAYLSFHSYGQYILYPWGYDYQLTQDRADLDRVARQAGTSITKSTGVKYTVGSSATTLYPAAGGSDDWAKGIAGIKYAYTIEMGDTGRYGFVLPARFIQYNGKDGVTFADTVARAIAQGRGKSVARNSSGSRRRGH", "length": 1132, "header": "tr|Q9W475-1|Q9W475_DROME Isoform 1 of Peptidase M14 domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG3108 PE=3 SV=2 CANONICAL=Q9W475-1" }, "isoforms": [ { "isoform_ac": "Q9W475-1", "url": "https://www.uniprot.org/uniprotkb/Q9W475/entry#Q9W475-1", "sequence": { "sequence": "MYNARSRGSAANEGISPKRIVTIGSLLLVLGLNQVASMSLDRLALERNELPADQQQQQQQDVLVDNMKLTSIPSADSSDMYMLVPDTVASQLEDTEHVNRNSIEADPESDPSGSSSSDMLMLESDSSPAMQLVELPSDITVAESQPETEHDTENDQQQPESIEEHVVLMKPASQEAQLEQTVDLATEAAPVPLNDELPEDEESPAATESAVEELEKESEAAMDDQVPEESEIQPEQVQPGEYQSESDGEQAETKPEIEAQPEVEAQPEAEAQPEAEPQLEVEPQPEVESQPEVESQPEVEAQPEVEPQSEVESQPEAESHSEPETQAEVEAQPEVESLPEAESQPEAESQPEREPEVEAEKISDNEVDTTEASLMETLVEGIEDGLTAAMDNLVPEELAEASDKQETELESEDQQSPVTEAIEEQAVPEIEQEKEKEPEQITLADETEQDSAQPSNEEPVEIAPEQHTEAEIAPAKIPEEGKPEEEVQVEEESKPVEESKPEEEIKQQEDAKPEEDDQNYAETQPAVTEVKPEETPADIPVEIPAEVPAEIPAEIPAEVPAEIPAESPAEIAAEVPAEIPAEIPAEIPAETPAETHAEIPADVPAQVVAEAPAETPAETPAEVPAEIPSKVQDEIQSDSTQAEPQVEKEAQQPEKETKPLESSLLTTIIPMVMPQPQVPSQPLQVQDSVLNYVNASFMQQQPSETDLPKTEEESPFNAHLRRYDGAQVWRIVVQTDKDKRMADELQSKYDGQLWKEVKQEVDYLLKPQVLAAAERHIRAANLSRIVLIDNLQRVIEKENPPAEKIAELQNRKGHRLTWQAYHRLEDIHGFIDYMAKTYPDICSTEIIGYSVEKRPLKILKISNGNARNPGIWIDGGMHAREWISPATVTYIANQLVEGWEDLPEHMRSINWYIHPVANPDGYEYSHTTDRLWRKNMRAHGRQCPGVDLNRNFGYKWGGKGTSASPCSQTYRGSKAFSEPETFYISKFISGFPRETFQAYLSFHSYGQYILYPWGYDYQLTQDRADLDRVARQAGTSITKSTGVKYTVGSSATTLYPAAGGSDDWAKGIAGIKYAYTIEMGDTGRYGFVLPARFIQYNGKDGVTFADTVARAIAQGRGKSVARNSSGSRRRGH", "length": 1132, "header": "tr|Q9W475-1|Q9W475_DROME Isoform 1 of Peptidase M14 domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG3108 PE=3 SV=2 CANONICAL=Q9W475-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W475", "url": "https://www.uniprot.org/uniprotkb/Q9W475" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W475", "url": "https://www.uniprot.org/uniprotkb/Q9W475" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W475", "url": "https://www.uniprot.org/uniprotkb/Q9W475" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W475", "url": "https://www.uniprot.org/uniprotkb/Q9W475" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W475", "url": "https://www.uniprot.org/uniprotkb/Q9W475" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W475", "url": "https://www.uniprot.org/uniprotkb/Q9W475" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W475", "url": "https://www.uniprot.org/uniprotkb/Q9W475" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W475", "url": "https://www.uniprot.org/uniprotkb/Q9W475" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W475", "url": "https://www.uniprot.org/uniprotkb/Q9W475" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W475", "url": "https://www.uniprot.org/uniprotkb/Q9W475" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W475", "url": "https://www.uniprot.org/uniprotkb/Q9W475" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG3108", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3108", "resource": "KEGG Pathway" }, { "id": "R-DME-2022377", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-2022377", "resource": "Reactome", "description": "Metabolism of Angiotensinogen to Angiotensins" } ], "orthologs": [ { "uniprot_canonical_ac": "B8JLQ9-1", "protein_name": "Carboxypeptidase O", "gene_name": "cpo", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMQASITSILVVLTLVAQDRLAGGLEHKSYDYTKYHTMDEISAWMNQMQRENPDVVSTMTYGQTYEKRNITLLKIGFSSTTPKKAIWMDCGIHAREWIAPAFCQHFVKEVLGSYKTDSRVNMLFKNLDFYITPVLNMDGYIYSWLNNSTRLWRKSRSPCHENSTCSGTDLNRNFYANWGMVGISRNCCSEVYNGATALSEPEAEAVTDFLGAHQNHLLCYLTIHSYGQLILVPYGHPNISAPNYDELMEVGLAAAKAIKAVHGKSYKVGSSPDVLYPNSGSSRDFARLIGIPYSFTFELRDEGQHGFILPEDQIQPTCQEAYEGAMSIINYVHDKNFKNTAITVTATLWTTLMALWISTSHVF", "length": 363 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070619-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070619-6#orthology", "database": "AGR" }, { "id": "FB:FBgn0029807", "url": "https://alliancegenome.org/gene/FB:FBgn0029807#orthology", "database": "AGR" }, { "id": "SGD:S000001174", "url": "https://alliancegenome.org/gene/SGD:S000001174#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7F2H8-1", "protein_name": "Carboxypeptidase A6", "gene_name": "cpa6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MALRSTDVSSNVKSAVLLGCVLILCTAPNNVDSYLYNNRYVGDQVFRIIPSSKPEVQAVKQLFQNLTVDLWQPNSASLIRENSSIDVHVRRDKTHWLRNHLHQEHIYYEVLISNLQTEIEKQTGYRSSRKRRSELQYDYEVYHPLEEIQSWMFEMNRTHSHLVDLFSIGQSYEGRPLYVLQLGKRTRFFKKAVWIDCGVHAREWIGPAFCQWFVKEALNSYQHDSSMRRLMNQLNFYIMPVFNVDGYHYSWKMDRFWRKTRSKIPKYHCRGVDANRNWKVKWCDEGASLHPCDDTYCGPFPESEPEVKAVAKFLRKHKKRVKAYISMHAYAQMLLYPYSYKYATIPNFNCVESAAQNAVSALYSAYGVRYRYGPASSTLYVSSGSSMDWAYKNGIPYAFAFELRDTGYYGFLLPEALINPTCTETMRAVKTIASGLLRKCTK", "length": 442 }, "evidence": [ { "id": "MGI:3045348", "url": "https://alliancegenome.org/gene/MGI:3045348#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7F897-1", "protein_name": "3.4.17.20", "gene_name": "cpb2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRALIQLAYFICFSIFLETCLCKVKHDQVLAITVSSQEHVEKVQNLTSHNETALWQPASPNYITTNSEVHLYIQSTSVQFVKEHLREHAITFRVLVENTAALVAMQIRNDTSDPRSGGVFYERYHSLEDIYYWINKTSREHSDMVKVILIGSSSEKRPLYVLKLSGKREEEVNRAMWMDCGIHAREWIAPAFCMWFVNYALAFYNQNTEITEMLNKMDIYILTVMNPDGYKYTWTTDRMWRKNRSENKDSYCAGVDLNRNFDANWCTKGASDDPCDPTYCGQFPESEPETQAVAKFLRSHKDTVKLYLSIHSYSQMLLFPYSCSYNEIPNHNELFELVKEASTKIRRYYRNNYKYGSGAKTIYLAPGGSDDWAYDLGIKYSFTFELQDRGQYGFLLPPSFIPQACNEALLAAKVIALHVINKTQ", "length": 424 }, "evidence": [ { "id": "MGI:1891837", "url": "https://alliancegenome.org/gene/MGI:1891837#orthology", "database": "AGR" }, { "id": "HGNC:2300", "url": "https://alliancegenome.org/gene/HGNC:2300#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1M4P0-1", "protein_name": "Carboxypeptidase A6", "gene_name": "Cpa6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKFLGKPRSLTAAFLPVCCLLLKILQPGHCHSYDNRYAGHKVIRLIPKSEEEALALKSVSHQLKVDLWQPSSISYVSEGTITDVRVTQNASRTLLAILQETNIQYKVLIEDLQKAVENENSVHTQRNRRSLSEYNYEVYHSLEDIQSWMHHLNQTQPGLVRVFPIGRSFEGRSLLIIQLGRKSQVYKRAVWIDCGIHAREWIGPAFCQWFVKEAILTYKTDPAMRKMLNHLYFYIMPVLNVDGYHFSWTHDRFWRKTRSRNSKFHCRGVDANRNWKVKWCDEGASADPCDDTYCGPFPESEPEVKAVANFLRKHRKRIRAYLSFHAYAQMLLYPYSYKHATIPNFSCVEFAAHKAVKALRSVHGIRYRHGPASQTLYVSSGNSMDWAYKNGIPYSFAFELRDTGYFGFLLPEMLIKPTCTETMLAVKNITMHLLKNCP", "length": 438 }, "evidence": [ { "id": "MGI:3045348", "url": "https://alliancegenome.org/gene/MGI:3045348#orthology", "database": "AGR" }, { "id": "FB:FBgn0029807", "url": "https://alliancegenome.org/gene/FB:FBgn0029807#orthology", "database": "AGR" }, { "id": "RGD:1311764", "url": "https://alliancegenome.org/gene/RGD:1311764#orthology", "database": "AGR" }, { "id": "SGD:S000001174", "url": "https://alliancegenome.org/gene/SGD:S000001174#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QJN9-1", "protein_name": "Carboxypeptidase B", "gene_name": "cpb1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKLFLLLGLVAVALCEPITFVGDKVLQLKPINDEHVTIIRELGEKIKLDFWKPRSADLVSIDMTVDIHVPAAQLAMVSTILQQSDMEVKVMIDNLQEAVKGQMDNRSPTKGHDYTKYNSWATINDWAISISSANPDLISRQSIGNTYEGRTMHLLKIGKNTGSNKPAVFMDCGFHAREWITHAFCQWFVNEAVSTYGSDPDMTNLLDRMDFFVLPVFNIDGYEYTWNRDRMWRKTRSKNSGSSCIGTDPNRNFNAGWCTVGASSNPCSDTYCGSSPESEIESKNLANFIRTNKSVIKAYLTVHSYSQLLLFPYSYKYDLAAHHSELMSVSQGAIAALRSLYGTKYTSGPGAATIYPAAGGSDDWAYDLGVKYSYTFELRDEGRYGFLLPESQIKPTCEETMLAVKYIANHVLNNLY", "length": 416 }, "evidence": [ { "id": "RGD:2390", "url": "https://alliancegenome.org/gene/RGD:2390#orthology", "database": "AGR" }, { "id": "SGD:S000001174", "url": "https://alliancegenome.org/gene/SGD:S000001174#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P00731-1", "protein_name": "Carboxypeptidase A1", "gene_name": "Cpa1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKRLLILSLLLEAVCGNENFVGHQVLRISAADEAQVQKVKELEDLEHLQLDFWRDAARAGIPIDVRVPFPSIQSVKAFLEYHGISYEIMIEDVQLLLDEEKQQMSAFQARALSTDSFNYATYHTLDEIYEFMDLLVAEHPQLVSKIQIGNTFEGRPIHVLKFSTGGTNRPAIWIDTGIHSREWVTQASGVWFAKKITKDYGQDPTFTAVLDNMDIFLEIVTNPDGFAYTHKTNRMWRKTRSHTQGSLCVGVDPNRNWDAGFGMAGASSNPCSETYRGKFPNSEVEVKSIVDFVTSHGNIKAFISIHSYSQLLLYPYGYTSEPAPDQAELDQLAKSAVTALTSLHGTKFKYGSIIDTIYQASGSTIDWTYSQGIKYSFTFELRDTGLRGFLLPASQIIPTAEETWLALLTIMDHTVKHPY", "length": 419 }, "evidence": [ { "id": "MGI:88478", "url": "https://alliancegenome.org/gene/MGI:88478#orthology", "database": "AGR" }, { "id": "FB:FBgn0029807", "url": "https://alliancegenome.org/gene/FB:FBgn0029807#orthology", "database": "AGR" }, { "id": "RGD:2388", "url": "https://alliancegenome.org/gene/RGD:2388#orthology", "database": "AGR" }, { "id": "SGD:S000001174", "url": "https://alliancegenome.org/gene/SGD:S000001174#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P15085-1", "protein_name": "Carboxypeptidase A1", "gene_name": "CPA1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRGLLVLSVLLGAVFGKEDFVGHQVLRISVADEAQVQKVKELEDLEHLQLDFWRGPAHPGSPIDVRVPFPSIQAVKIFLESHGISYETMIEDVQSLLDEEQEQMFAFRSRARSTDTFNYATYHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTGGSKRPAIWIDTGIHSREWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWRKTRSHTAGSLCIGVDPNRNWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIVDFVKDHGNIKAFISIHSYSQLLMYPYGYKTEPVPDQDELDQLSKAAVTALASLYGTKFNYGSIIKAIYQASGSTIDWTYSQGIKYSFTFELRDTGRYGFLLPASQIIPTAKETWLALLTIMEHTLNHPY", "length": 419 }, "evidence": [ { "id": "MGI:88478", "url": "https://alliancegenome.org/gene/MGI:88478#orthology", "database": "AGR" }, { "id": "RGD:2388", "url": "https://alliancegenome.org/gene/RGD:2388#orthology", "database": "AGR" }, { "id": "SGD:S000001174", "url": "https://alliancegenome.org/gene/SGD:S000001174#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P15086-1", "protein_name": "Carboxypeptidase B", "gene_name": "CPB1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLALLVLVTVALASAHHGGEHFEGEKVFRVNVEDENHINIIRELASTTQIDFWKPDSVTQIKPHSTVDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVVEAQFDSRVRATGHSYEKYNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNKPAIFMDCGFHAREWISPAFCQWFVREAVRTYGREIQVTELLDKLDFYVLPVLNIDGYIYTWTKSRFWRKTRSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNKLSSIKAYLTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKELASLHGTKYTYGPGATTIYPAAGGSDDWAYDQGIRYSFTFELRDTGRYGFLLPESQIRATCEETFLAIKYVASYVLEHLY", "length": 417 }, "evidence": [ { "id": "SGD:S000001174", "url": "https://alliancegenome.org/gene/SGD:S000001174#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P15088-1", "protein_name": "Mast cell carboxypeptidase A", "gene_name": "CPA3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRLILPVGLIATTLAIAPVRFDREKVFRVKPQDEKQADIIKDLAKTNELDFWYPGATHHVAANMMVDFRVSEKESQAIQSALDQNKMHYEILIHDLQEEIEKQFDVKEDIPGRHSYAKYNNWEKIVAWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKIGEKNERRKAIFTDCGIHAREWVSPAFCQWFVYQATKTYGRNKIMTKLLDRMNFYILPVFNVDGYIWSWTKNRMWRKNRSKNQNSKCIGTDLNRNFNASWNSIPNTNDPCADNYRGSAPESEKETKAVTNFIRSHLNEIKVYITFHSYSQMLLFPYGYTSKLPPNHEDLAKVAKIGTDVLSTRYETRYIYGPIESTIYPISGSSLDWAYDLGIKHTFAFELRDKGKFGFLLPESRIKPTCRETMLAVKFIAKYILKHTS", "length": 417 }, "evidence": [ { "id": "MGI:88479", "url": "https://alliancegenome.org/gene/MGI:88479#orthology", "database": "AGR" }, { "id": "RGD:2390", "url": "https://alliancegenome.org/gene/RGD:2390#orthology", "database": "AGR" }, { "id": "SGD:S000001174", "url": "https://alliancegenome.org/gene/SGD:S000001174#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P15089-1", "protein_name": "Mast cell carboxypeptidase A", "gene_name": "Cpa3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRFFLLMAVIYTTLAIAPVHFDREKVFRVKLQNEKHASVLKNLTQSIELDFWYPDAIHDIAVNMTVDFRVSEKESQTIQSTLEQHKIHYEILIHDLQEEIEKQFDVKDEIAGRHSYAKYNDWDKIVSWTEKMLEKHPEMVSRIKIGSTVEDNPLYVLKIGKKDGERKAIFMDCGIHAREWISPAFCQWFVYQATKSYGKNKIMTKLLDRMNFYVLPVFNVDGYIWSWTQDRMWRKNRSRNQNSTCIGTDLNRNFDVSWDSSPNTNKPCLNVYRGPAPESEKETKAVTNFIRSHLNSIKAYITFHSYSQMLLIPYGYTFKLPPNHQDLLKVARIATDALSTRYETRYIYGPIASTIYKTSGSSLDWVYDLGIKHTFAFELRDKGKSGFLLPESRIKPTCKETMLSVKFIAKYILKNTS", "length": 417 }, "evidence": [ { "id": "MGI:88479", "url": "https://alliancegenome.org/gene/MGI:88479#orthology", "database": "AGR" }, { "id": "FB:FBgn0029807", "url": "https://alliancegenome.org/gene/FB:FBgn0029807#orthology", "database": "AGR" }, { "id": "RGD:2390", "url": "https://alliancegenome.org/gene/RGD:2390#orthology", "database": "AGR" }, { "id": "SGD:S000001174", "url": "https://alliancegenome.org/gene/SGD:S000001174#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P19222-1", "protein_name": "Carboxypeptidase A2", "gene_name": "Cpa2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLTLLLAALLGYIYCQETFVGDQVLEIIPSHEEQIRTLLQLEAEEHLELDFWKSPTIPGETVHVRVPFASIQAVKVFLESQGIDYSIMIEDVQVLLDQEREEMLFNQQRERGGNFNFEAYHTLEEIYQEMDNLVAENPGLVSKVNLGSSFENRPMNVLKFSTGGDKPAIWLDAGIHAREWVTQATALWTANKIASDYGTDPAITSLLNTLDIFLLPVTNPDGYVFSQTTNRMWRKTRSKRSGSGCVGVDPNRNWDANFGGPGASSSPCSDSYHGPKPNSEVEVKSIVDFIKSHGKVKAFITLHSYSQLLMFPYGYKCTKPDDFNELDEVAQKAAQALKRLHGTSYKVGPICSVIYQASGGSIDWAYDLGIKYSFAFELRDTAFYGFLLPAKQILPTAEETWLGLKTIMEHVRDHPY", "length": 417 }, "evidence": [ { "id": "SGD:S000001174", "url": "https://alliancegenome.org/gene/SGD:S000001174#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P19223-1", "protein_name": "Carboxypeptidase B", "gene_name": "Cpb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLLLLALVSVALAHASEEHFDGNRVYRVSVHGEDHVNLIQELANTKEIDFWKPDSATQVKPLTTVDFHVKAEDVADVENFLEENEVHYEVLISNVRNALESQFDSHTRASGHSYTKYNKWETIEAWIQQVATDNPDLVTQSVIGTTFEGRNMYVLKIGKTRPNKPAIFIDCGFHAREWISPAFCQWFVREAVRTYNQEIHMKQLLDELDFYVLPVVNIDGYVYTWTKDRMWRKTRSTMAGSSCLGVRPNRNFNAGWCEVGASRSPCSETYCGPAPESEKETKALADFIRNNLSTIKAYLTIHSYSQMMLYPYSYDYKLPENYEELNALVKGAAKELATLHGTKYTYGPGATTIYPAAGGSDDWSYDQGIKYSFTFELRDTGFFGFLLPESQIRQTCEETMLAVKYIANYVREHLY", "length": 415 }, "evidence": [ { "id": "SGD:S000001174", "url": "https://alliancegenome.org/gene/SGD:S000001174#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P21961-1", "protein_name": "Mast cell carboxypeptidase A", "gene_name": "Cpa3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LMGVIYSTLAIAPVQFDREKVFRVKLQDEKQASILKNLTQTIELDFWYPDAIHDIAVNMTVDFRVTEKESQTIQSTLEQHKMDYEILINDLQEEIDKQFDVKEEIAGRHSYAKYNDWNKIVSWTEKMVEKHPEMVSRIKIGSTVEDNPLYVLKIGRKDGERKAIFMDCGIHAREWVSPAFCQWFVYQAAKSYGKNKIMTKLLDRMNFYVLPVFNVDGYIWSWTKDRMWRKNRSKNPNSTCIGTDLNRNFDVSWDSSPNTDNPCLSVYRGPAPESEKETKAVTNFIRSHLNSIKAYITFHSYSQMLLFPYGYTIKLPPNHQDLLKVARIATDVLSSRYETRYIYGPIASTIYKTSGSSLDWAYDLGIKHTFAFELRDKGKSGFLLPESRIKPTCKETMLSVKFIAKYILKHTS", "length": 412 }, "evidence": [ { "id": "MGI:88479", "url": "https://alliancegenome.org/gene/MGI:88479#orthology", "database": "AGR" }, { "id": "FB:FBgn0029807", "url": "https://alliancegenome.org/gene/FB:FBgn0029807#orthology", "database": "AGR" }, { "id": "RGD:2390", "url": "https://alliancegenome.org/gene/RGD:2390#orthology", "database": "AGR" }, { "id": "SGD:S000001174", "url": "https://alliancegenome.org/gene/SGD:S000001174#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P38836-1", "protein_name": "Inactive metallocarboxypeptidase ECM14", "gene_name": "ECM14", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLHMNSLWGCFLFVLLAVTGAVQGLQEDYSEYAVYRFTSDNYSTLVRDVIAPLTDDYDVWTRSNNFIDIKLPKEIGEQINDGQVIIDNMNELIQNTLPTSQMMAREQAVFENDYDFFFNEYRDLDTIYMWLDLLERSFPSLVAVEHLGRTFEGRELKALHISGNKPESNPEKKTIVITGGIHAREWISVSTVCWALYQLLNRYGSSKKETKYLDDLDFLVIPVFNPDGYAYTWSHDRLWRKNRQRTHVPQCLGIDIDHSFGFQWEKAHTHACSEEYSGETPFEAWEASAWYKYINETKGDYKIYGYIDMHSYSQEILYPYAYSCDALPRDLENLLELSYGLSKAIRSKSGRNYDVISACKDRGSDIFPGLGAGSALDFMYHHRAHWAFQLKLRDTGNHGFLLPPENIKPVGKETYAALKYFCDFLLDPEI", "length": 430 }, "evidence": [ { "id": "MGI:3045348", "url": "https://alliancegenome.org/gene/MGI:3045348#orthology", "database": "AGR" }, { "id": "MGI:1891837", "url": "https://alliancegenome.org/gene/MGI:1891837#orthology", "database": "AGR" }, { "id": "MGI:88478", "url": "https://alliancegenome.org/gene/MGI:88478#orthology", "database": "AGR" }, { "id": "MGI:1921899", "url": "https://alliancegenome.org/gene/MGI:1921899#orthology", "database": "AGR" }, { "id": "MGI:88479", "url": "https://alliancegenome.org/gene/MGI:88479#orthology", "database": "AGR" }, { "id": "HGNC:2300", "url": "https://alliancegenome.org/gene/HGNC:2300#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070619-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070619-6#orthology", "database": "AGR" }, { "id": "FB:FBgn0029807", "url": "https://alliancegenome.org/gene/FB:FBgn0029807#orthology", "database": "AGR" }, { "id": "RGD:2390", "url": "https://alliancegenome.org/gene/RGD:2390#orthology", "database": "AGR" }, { "id": "RGD:71035", "url": "https://alliancegenome.org/gene/RGD:71035#orthology", "database": "AGR" }, { "id": "RGD:1311764", "url": "https://alliancegenome.org/gene/RGD:1311764#orthology", "database": "AGR" }, { "id": "RGD:2388", "url": "https://alliancegenome.org/gene/RGD:2388#orthology", "database": "AGR" }, { "id": "SGD:S000001174", "url": "https://alliancegenome.org/gene/SGD:S000001174#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P48052-1", "protein_name": "Carboxypeptidase A2", "gene_name": "CPA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAMRLILFFGALFGHIYCLETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTPGETAHVRVPFVNVQAVKVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGNFNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDKPAIWLDAGIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSHGKVKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPICSVIYQASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHVRDHPY", "length": 419 }, "evidence": [ { "id": "SGD:S000001174", "url": "https://alliancegenome.org/gene/SGD:S000001174#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q0E9F9-1", "protein_name": "Zinc carboxypeptidase A 1", "gene_name": "Dmel\\CG2915", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGNKIINMPAARIGTQWLVILCVAMAASGTNLDSGICPVAGDSGCRGNPPDQARYDNYRIYNVEFENQEQIELFQKLEEQSDSLTFIGHAREVGQKLSILVAAHRVADIADLLKTYKVKHRVLTYNFQEKIDRNLAEVQPESIDASQLDWQHFFHLKTIYEWLDKMVEKYPNRVTVLDMGSSTQGNAIKGVKLTSNANNKAIFIESGIHAREWISPAAATYIINQLLTSQDPKVQQLAQDYNWIIFPCVNPDGYKYTFEHDRMWRKNRQLFGTCRGVDLNRNYPDHWNSTGSSSDPTRYDFAGPSAGSELETKRLIDFIRANAGKEQIKTYIALHSYSQMLMFPYGYTKERVSNYDDLQEFGKKASAAIKAENGRDYVSGSLFETIYPSSGGSMDWAHSEAGIPIAYTFELRGPPDSQDLFILPAVEIQPTASEAFTAIRAIVEAAAEKGYYK", "length": 453 }, "evidence": [ { "id": "MGI:3045348", "url": "https://alliancegenome.org/gene/MGI:3045348#orthology", "database": "AGR" }, { "id": "MGI:1891837", "url": "https://alliancegenome.org/gene/MGI:1891837#orthology", "database": "AGR" }, { "id": "MGI:88478", "url": "https://alliancegenome.org/gene/MGI:88478#orthology", "database": "AGR" }, { "id": "MGI:1921899", "url": "https://alliancegenome.org/gene/MGI:1921899#orthology", "database": "AGR" }, { "id": "MGI:88479", "url": "https://alliancegenome.org/gene/MGI:88479#orthology", "database": "AGR" }, { "id": "HGNC:2300", "url": "https://alliancegenome.org/gene/HGNC:2300#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070619-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070619-6#orthology", "database": "AGR" }, { "id": "RGD:2390", "url": "https://alliancegenome.org/gene/RGD:2390#orthology", "database": "AGR" }, { "id": "RGD:71035", "url": "https://alliancegenome.org/gene/RGD:71035#orthology", "database": "AGR" }, { "id": "RGD:1311764", "url": "https://alliancegenome.org/gene/RGD:1311764#orthology", "database": "AGR" }, { "id": "RGD:2388", "url": "https://alliancegenome.org/gene/RGD:2388#orthology", "database": "AGR" }, { "id": "SGD:S000001174", "url": "https://alliancegenome.org/gene/SGD:S000001174#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q504N0-1", "protein_name": "Carboxypeptidase A2", "gene_name": "Cpa2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRLTPLLVALFGYIYCQETFVGDQVLEVIPNDEEQIKTLLQLEAEEHLELDFWKSPSVPRQTVHVRVPFASIQDVKVFLESQGITYSIMIEDVQVLLDQEREEMLFNQQRERGTNFNFGAYHTLEEIYQEMDNLVAENPGLVSKVNIGSSFENRPMNVLKFSTGGDKPAIWLDAGIHAREWVTQATALWTANKIASDYGTDPAITSLLNTLDVFLLPVTNPDGYVFSQTSNRMWRKTRSKRSGSFCVGVDPNRNWDANFGGPGASSNPCSDSYHGPSPNSEVEVKSIVDFIKSHGKVKAFITLHSYSQLLMFPYGYKCAKPDDFNELDEVAQRAAQSLKRLHGTSYKVGPICSVIYQASGGSIDWAYDLGIKYSFAFELRDTGYYGFLLPAKQILPTAEETWLGLKTIMEHVRDHPY", "length": 417 }, "evidence": [ { "id": "SGD:S000001174", "url": "https://alliancegenome.org/gene/SGD:S000001174#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5U901-1", "protein_name": "Carboxypeptidase A6", "gene_name": "Cpa6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNFLGNPRSHTAAFLPVCWLLLNILKPGHCHSYDNRYAGDKVIRLIPKSEEEALALKNIYHQLKVDLWQPSSISYVSEGTITDVHISQNASRTLLAFLQETHIYYKVLIEDLQKAVENENSLQTQRNRRSLSEYNYEVYHSLEDIQSWLHHLNQTQPGLVRVFSIGRSYEGRPLFIMQLGRKSRAYKRAVWIDCGIHAREWIGPAFCQWFVREAILTYKTDPAMKKMLNHLYFYIMPVFNVDGYHFSWTHDRFWRKTRSRDSKFRCRGVDANRNWKVKWCDEGASAHPCDDTYCGPFPESEPEVKAVANFLRKHRKRIRAYLSFHAYAQMLLYPYSYKYATIPNFSCVEFAAHKAVKALRSVHGIRYRHGPASQTLYVSSGNSMDWAYKNGIPYAFAFELRDTGHFGFLLPEMLIKPTCTETMLAVKNITMHLLKKCP", "length": 438 }, "evidence": [ { "id": "MGI:3045348", "url": "https://alliancegenome.org/gene/MGI:3045348#orthology", "database": "AGR" }, { "id": "FB:FBgn0029807", "url": "https://alliancegenome.org/gene/FB:FBgn0029807#orthology", "database": "AGR" }, { "id": "RGD:1311764", "url": "https://alliancegenome.org/gene/RGD:1311764#orthology", "database": "AGR" }, { "id": "SGD:S000001174", "url": "https://alliancegenome.org/gene/SGD:S000001174#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6P8K8-1", "protein_name": "Carboxypeptidase A4", "gene_name": "Cpa4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKWLLFFGALIGAGICGRDKFFGDQVFRINVRNGDEIRKLTELVNSDHLKLSVWKSPSTFDRPVDILVPSVSLLPVKSFLKSQGLDYSVTIEDLQALLDNEDEEMQHNEGIERSGDFNYGAYHPLEAIYHEMDSIATDFPELVSRVKIGETFEKRPMYVLKFSTGGGKKRPAIWLNAGIHAREWISQATAIWTARKIVTDYKKDPAITSILKKVDIFLLPVANPDGYVYTQSQNRLWRKTRSRNPGSRCVGADPNRNWNASFAGEGTSDNPCSEVYHGSHPNSEVEVKSVVDFIQKHGNFKCFIDLHSYSQLLMYPYGYTVKKAPDAEELDDVARNAAQALASLSGTKYRVGPTCTTVYPASGSSVDWAYDNGIKYAFTFELRDTGYYGFLLPASQIIPTAEETWLGLKTIMEHVRDHLY", "length": 420 }, "evidence": [ { "id": "SGD:S000001174", "url": "https://alliancegenome.org/gene/SGD:S000001174#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TPZ8-1", "protein_name": "Carboxypeptidase A1", "gene_name": "Cpa1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKRLLVLSVLLAAVFGNENFVGHQVLRISATDEAQVQKVRELEELEHLKLDFWRDPARAGLPIDVRVPFPTIQSVKAFLEYHDISYEIMIEDVQSLLDEEKQQMSAFQARALSTDAFNYATYHTLDEIYEFMDLLVTEHPQLVSKIQIGSTFEGRPINVLKFSTGGTNRPAIWIDTGIHSREWVTQASGVWFAKKITKDYGQEPTLTAILDNMDIFLEIVTNPDGFVYTHKTNRMWRKTRSHTEGSLCVGVDPNRNWDAAFGMPGASSNPCSETYRGKFPNSEVEVKSIVDFVTSHGNIKAFISIHSYSQLLLYPYGYTSEPAPDKEELDQLAKSAVTALTSLHGTKFKYGSIIDTIYQASGSTIDWTYSQGIKYSFTFELRDTGLRGFLLPASQIIPTAEETWLALLTIMDHTVKHPY", "length": 419 }, "evidence": [ { "id": "MGI:88478", "url": "https://alliancegenome.org/gene/MGI:88478#orthology", "database": "AGR" }, { "id": "FB:FBgn0029807", "url": "https://alliancegenome.org/gene/FB:FBgn0029807#orthology", "database": "AGR" }, { "id": "RGD:2388", "url": "https://alliancegenome.org/gene/RGD:2388#orthology", "database": "AGR" }, { "id": "SGD:S000001174", "url": "https://alliancegenome.org/gene/SGD:S000001174#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IVL8-1", "protein_name": "Carboxypeptidase O", "gene_name": "CPO", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKPLLETLYLLGMLVPGGLGYDRSLAQHRQEIVDKSVSPWSLETYSYNIYHPMGEIYEWMREISEKYKEVVTQHFLGVTYETHPMYYLKISQPSGNPKKIIWMDCGIHAREWIAPAFCQWFVKEILQNHKDNSSIRKLLRNLDFYVLPVLNIDGYIYTWTTDRLWRKSRSPHNNGTCFGTDLNRNFNASWCSIGASRNCQDQTFCGTGPVSEPETKAVASFIESKKDDILCFLTMHSYGQLILTPYGYTKNKSSNHPEMIQVGQKAANALKAKYGTNYRVGSSADILYASSGSSRDWARDIGIPFSYTFELRDSGTYGFVLPEAQIQPTCEETMEAVLSVLDDVYAKHWHSDSAGRVTSATMLLGLLVSCMSLL", "length": 374 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070619-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070619-6#orthology", "database": "AGR" }, { "id": "SGD:S000001174", "url": "https://alliancegenome.org/gene/SGD:S000001174#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8N4T0-1", "protein_name": "Carboxypeptidase A6", "gene_name": "CPA6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKCLGKRRGQAAAFLPLCWLFLKILQPGHSHLYNNRYAGDKVIRFIPKTEEEAYALKKISYQLKVDLWQPSSISYVSEGTVTDVHIPQNGSRALLAFLQEANIQYKVLIEDLQKTLEKGSSLHTQRNRRSLSGYNYEVYHSLEEIQNWMHHLNKTHSGLIHMFSIGRSYEGRSLFILKLGRRSRLKRAVWIDCGIHAREWIGPAFCQWFVKEALLTYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWRKTRSRNSRFRCRGVDANRNWKVKWCDEGASMHPCDDTYCGPFPESEPEVKAVANFLRKHRKHIRAYLSFHAYAQMLLYPYSYKYATIPNFRCVESAAYKAVNALQSVYGVRYRYGPASTTLYVSSGSSMDWAYKNGIPYAFAFELRDTGYFGFLLPEMLIKPTCTETMLAVKNITMHLLKKCP", "length": 437 }, "evidence": [ { "id": "MGI:3045348", "url": "https://alliancegenome.org/gene/MGI:3045348#orthology", "database": "AGR" }, { "id": "RGD:1311764", "url": "https://alliancegenome.org/gene/RGD:1311764#orthology", "database": "AGR" }, { "id": "SGD:S000001174", "url": "https://alliancegenome.org/gene/SGD:S000001174#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R4H4-1", "protein_name": "Carboxypeptidase A5", "gene_name": "Cpa5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQGTQRGGLVPGLSPLDRRTLLFCNFILAVAWGQVNFTGDQVLRVLAKNEKQLSLLRDLETQKPQKVDFWRGPARPSLPVDMRVPFSELPSVKAYLKSHGLAYSIMIKDIQVLLDEERDAMAKSRRLERSTNSFSYSSYHTLDEIYSWIDNFVAEHSNLVSKIHIGKSFENRSILVLKFSTGGPNRPAIWIDTGIHSREWITHATGIWISQKIVNAYGKDHVLKRILNTMDIFIEIVTNPDGFAFTHSMNRLWRKNKSSQPGIFCIGVDLNRNWKAGFGGNGSNKNPCSETYRGPAPESEPEVAAIVDFITGHGNFKAMISIHSYSQMVMYPYGHSLEPVPNHEELFNLAKDAVKALNKVHGIQYIFGSISTTLYSASGISVDWAYDSGIKYAFSFELRDTGQYGFLLPASQIVPTAEETWMALQTIMKHTLNHPY", "length": 436 }, "evidence": [ { "id": "MGI:1921899", "url": "https://alliancegenome.org/gene/MGI:1921899#orthology", "database": "AGR" }, { "id": "FB:FBgn0029807", "url": "https://alliancegenome.org/gene/FB:FBgn0029807#orthology", "database": "AGR" }, { "id": "SGD:S000001174", "url": "https://alliancegenome.org/gene/SGD:S000001174#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WXQ8-1", "protein_name": "Carboxypeptidase A5", "gene_name": "CPA5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQGTPGGGTRPGPSPVDRRTLLVFSFILAAALGQMNFTGDQVLRVLAKDEKQLSLLGDLEGLKPQKVDFWRGPARPSLPVDMRVPFSELKDIKAYLESHGLAYSIMIKDIQVLLDEERQAMAKSRRLERSTNSFSYSSYHTLEEIYSWIDNFVMEHSDIVSKIQIGNSFENQSILVLKFSTGGSRHPAIWIDTGIHSREWITHATGIWTANKIVSDYGKDRVLTDILNAMDIFIELVTNPDGFAFTHSMNRLWRKNKSIRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETYHGPSPQSEPEVAAIVNFITAHGNFKALISIHSYSQMLMYPYGRLLEPVSNQRELYDLAKDAVEALYKVHGIEYIFGSISTTLYVASGITVDWAYDSGIKYAFSFELRDTGQYGFLLPATQIIPTAQETWMALRTIMEHTLNHPY", "length": 436 }, "evidence": [ { "id": "MGI:1921899", "url": "https://alliancegenome.org/gene/MGI:1921899#orthology", "database": "AGR" }, { "id": "SGD:S000001174", "url": "https://alliancegenome.org/gene/SGD:S000001174#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q96IY4-1", "protein_name": "Carboxypeptidase B2", "gene_name": "CPB2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKLCSLAVLVPIVLFCEQHVFAFQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTADLIVKKKQVHFFVNASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYYEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKISKNTRYTHGHGSETLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVIRNV", "length": 423 }, "evidence": [ { "id": "MGI:1891837", "url": "https://alliancegenome.org/gene/MGI:1891837#orthology", "database": "AGR" }, { "id": "HGNC:2300", "url": "https://alliancegenome.org/gene/HGNC:2300#orthology", "database": "AGR" }, { "id": "FB:FBgn0029807", "url": "https://alliancegenome.org/gene/FB:FBgn0029807#orthology", "database": "AGR" }, { "id": "RGD:71035", "url": "https://alliancegenome.org/gene/RGD:71035#orthology", "database": "AGR" }, { "id": "SGD:S000001174", "url": "https://alliancegenome.org/gene/SGD:S000001174#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9EQV9-1", "protein_name": "Carboxypeptidase B2", "gene_name": "Cpb2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKLYGLGVLVAIILYEKHGLAFQSGHVLSALPRTSRQVQLLQNLTTTYEVVLWQPVTAEFIEKKKEVHFFVNASDVNSVKAYLNASRIPFNVLMNNVEDLIQQQTSNDTVSPRASSSYYEQYHSLNEIYSWIEVITEQHPDMLQKIYIGSSYEKYPLYVLKVSGKEHRVKNAIWIDCGIHAREWISPAFCLWFIGYVTQFHGKENTYTRLLRHVDFYIMPVMNVDGYDYTWKKNRMWRKNRSVHMNNRCVGTDLNRNFASKHWCEKGASSFSCSETYCGLYPESEPEVKAVADFLRRNINHIKAYISMHSYSQQILFPYSYNRSKSKDHEELSLVASEAVRAIESINKNTRYTHGSGSESLYLAPGGSDDWIYDLGIKYSFTIELRDTGRYGFLLPERFIKPTCAEALAAVSKIAWHVIRNS", "length": 422 }, "evidence": [ { "id": "MGI:1891837", "url": "https://alliancegenome.org/gene/MGI:1891837#orthology", "database": "AGR" }, { "id": "HGNC:2300", "url": "https://alliancegenome.org/gene/HGNC:2300#orthology", "database": "AGR" }, { "id": "FB:FBgn0029807", "url": "https://alliancegenome.org/gene/FB:FBgn0029807#orthology", "database": "AGR" }, { "id": "RGD:71035", "url": "https://alliancegenome.org/gene/RGD:71035#orthology", "database": "AGR" }, { "id": "SGD:S000001174", "url": "https://alliancegenome.org/gene/SGD:S000001174#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9JHH6-1", "protein_name": "Carboxypeptidase B2", "gene_name": "Cpb2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLHGLGILVAIILYEQHGFAFQSGQVLSALPRTSRQVQLLQNLTTTYEVVLWQPVTAEFIEKKKEVHFFVNASDVDSVKAHLNVSRIPFNVLMNNVEDLIEQQTFNDTVSPRASASYYEQYHSLNEIYSWIEVITEQHPDMLQKIYIGSSFEKYPLYVLKVSGKEQRIKNAIWIDCGIHAREWISPAFCLWFIGYVTQFHGKENLYTRLLRHVDFYIMPVMNVDGYDYTWKKNRMWRKNRSAHKNNRCVGTDLNRNFASKHWCEKGASSSSCSETYCGLYPESEPEVKAVADFLRRNIDHIKAYISMHSYSQQILFPYSYNRSKSKDHEELSLVASEAVRAIESINKNTRYTHGSGSESLYLAPGGSDDWIYDLGIKYSFTIELRDTGRYGFLLPERYIKPTCAEALAAISKIVWHVIRNT", "length": 422 }, "evidence": [ { "id": "MGI:1891837", "url": "https://alliancegenome.org/gene/MGI:1891837#orthology", "database": "AGR" }, { "id": "HGNC:2300", "url": "https://alliancegenome.org/gene/HGNC:2300#orthology", "database": "AGR" }, { "id": "FB:FBgn0029807", "url": "https://alliancegenome.org/gene/FB:FBgn0029807#orthology", "database": "AGR" }, { "id": "RGD:71035", "url": "https://alliancegenome.org/gene/RGD:71035#orthology", "database": "AGR" }, { "id": "SGD:S000001174", "url": "https://alliancegenome.org/gene/SGD:S000001174#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UI42-1", "protein_name": "Carboxypeptidase A4", "gene_name": "CPA4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRWILFIGALIGSSICGQEKFFGDQVLRINVRNGDEISKLSQLVNSNNLKLNFWKSPSSFNRPVDVLVPSVSLQAFKSFLRSQGLEYAVTIEDLQALLDNEDDEMQHNEGQERSSNNFNYGAYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFSTGKGVRRPAVWLNAGIHSREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQTQNRLWRKTRSRNPGSSCIGADPNRNWNASFAGKGASDNPCSEVYHGPHANSEVEVKSVVDFIQKHGNFKGFIDLHSYSQLLMYPYGYSVKKAPDAEELDKVARLAAKALASVSGTEYQVGPTCTTVYPASGSSIDWAYDNGIKFAFTFELRDTGTYGFLLPANQIIPTAEETWLGLKTIMEHVRDNLY", "length": 421 }, "evidence": [ { "id": "SGD:S000001174", "url": "https://alliancegenome.org/gene/SGD:S000001174#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VCM8-1", "protein_name": "Zinc carboxypeptidase A 1", "gene_name": "Dmel\\CG4408", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MYACQSALQENEMEIFYTDFKLRRIKMLPKGGTPKTWLLLLLVSSVCVIQESKASSFCTKADQCALDEEIKTAADSVQARYDHTRIYQVELASEEHVRLFQALEQASDSCSFMGHARQPGQKLTIMVTGAKVADFDDLVHSYNVTHRVLNYNFQALIDANYLEVAPEDTKPEEFDWKRYHPLESINAWLKKLAETHPEVLLVELGVSAQGRPILGVQIAFDNENRTTVFVESGIHAREWIAPATATYIIDQLVNSKDSAVQALARSQRWYIFPTVNPDGYQYTFKGDRMWRKNRALFGICRGVDLNRNFPFHWNVTGASGDPCRYDYSGPSAASEVETQRMIEFIRHRVESERIRTFISLHSYSQMIMFPYGHSAERVDNYHDLTDIGKLAANKIKDVSGRIYKSGSIYETIYPSSGGSKDWAHGQLKIPITFSYELRGPADSEDLFILSAKEIEPTAAEAFASIQTIVQEAGKRGYYQ", "length": 479 }, "evidence": [ { "id": "MGI:3045348", "url": "https://alliancegenome.org/gene/MGI:3045348#orthology", "database": "AGR" }, { "id": "MGI:1891837", "url": "https://alliancegenome.org/gene/MGI:1891837#orthology", "database": "AGR" }, { "id": "MGI:88478", "url": "https://alliancegenome.org/gene/MGI:88478#orthology", "database": "AGR" }, { "id": "MGI:1921899", "url": "https://alliancegenome.org/gene/MGI:1921899#orthology", "database": "AGR" }, { "id": "MGI:88479", "url": "https://alliancegenome.org/gene/MGI:88479#orthology", "database": "AGR" }, { "id": "HGNC:2300", "url": "https://alliancegenome.org/gene/HGNC:2300#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070619-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070619-6#orthology", "database": "AGR" }, { "id": "RGD:2390", "url": "https://alliancegenome.org/gene/RGD:2390#orthology", "database": "AGR" }, { "id": "RGD:71035", "url": "https://alliancegenome.org/gene/RGD:71035#orthology", "database": "AGR" }, { "id": "RGD:1311764", "url": "https://alliancegenome.org/gene/RGD:1311764#orthology", "database": "AGR" }, { "id": "RGD:2388", "url": "https://alliancegenome.org/gene/RGD:2388#orthology", "database": "AGR" }, { "id": "SGD:S000001174", "url": "https://alliancegenome.org/gene/SGD:S000001174#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VL86-1", "protein_name": "Zinc carboxypeptidase A 1", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSLNKCLLFALLAIVASASVSAERVRYDNYRMYKVNSENAKQLEVLKDLEGSSDSIMFLDGVHLVGADIQIIVAPHKVPDFLEILGKSEIKYELQSRDVQKSLDEIDEKVAIKGRATTAYNWAQYYELDDTYAWLQSLAQTNPGVVTLIEGGKTYQGRSILGVKITKGGETINGKAKPGIFLEAGIHAREWIAPAAATFIINQLLTSEVENIKELAENYTWYVLPHANPDGYVYTHTTNRLWRKTRTPYGSCFGADPNRNWGFHWNEVGASSSACSDTYAGPSAFSEIETLSLSKFIEGLKGKVQLYLSLHAYSQYLLYPYGHTSDLPDNVADFEKVFDASIAAVNKRYGTTYTGGNIYDAIYPAAGASVDWAYGTQDVRMAFCYELRPSSTSYLTGFKLPAEQIVPASEELLDSIVAMATEVKSLGYFD", "length": 430 }, "evidence": [ { "id": "MGI:3045348", "url": "https://alliancegenome.org/gene/MGI:3045348#orthology", "database": "AGR" }, { "id": "MGI:1891837", "url": "https://alliancegenome.org/gene/MGI:1891837#orthology", "database": "AGR" }, { "id": "MGI:88478", "url": "https://alliancegenome.org/gene/MGI:88478#orthology", "database": "AGR" }, { "id": "MGI:1921899", "url": "https://alliancegenome.org/gene/MGI:1921899#orthology", "database": "AGR" }, { "id": "MGI:88479", "url": "https://alliancegenome.org/gene/MGI:88479#orthology", "database": "AGR" }, { "id": "HGNC:2300", "url": "https://alliancegenome.org/gene/HGNC:2300#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070619-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070619-6#orthology", "database": "AGR" }, { "id": "RGD:2390", "url": "https://alliancegenome.org/gene/RGD:2390#orthology", "database": "AGR" }, { "id": "RGD:71035", "url": "https://alliancegenome.org/gene/RGD:71035#orthology", "database": "AGR" }, { "id": "RGD:1311764", "url": "https://alliancegenome.org/gene/RGD:1311764#orthology", "database": "AGR" }, { "id": "RGD:2388", "url": "https://alliancegenome.org/gene/RGD:2388#orthology", "database": "AGR" }, { "id": "SGD:S000001174", "url": "https://alliancegenome.org/gene/SGD:S000001174#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VL87-1", "protein_name": "Peptidase M14 domain-containing protein", "gene_name": "Dmel\\CG4017", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKLLLLLLSVNILIFCLAERQRFDNYKVYRVSPVKANQLEGLRSLEANSEDALVLNNLHLGPTDFLVAPDFDGTFLKLVKDLDLSPELIDANAQTSLSLDIEPIADANRRSDDYSWSEYHELNDTHRWMQNLVGKYPDVVSVFVAGQSYEGRELLGLRINHNDGRAEKQSIFLEAGMHAREWIGPATATYFANELLSSQQQEIMNLARSYVWYILPHANPDGYVYTHKTNRMWRKTRSPQDKNCVGTDPNRNWDFHWREVGASSDPCSESYAGPKAFSEPEVQTLSQFLKSVPEPMFMFLSLHSFSQLLLYPYGHTSALPENHRQLEQIFNTAVGAMKRRYGTRYTGGNVYDAIYPAAGSSMDWAYGVLNVKYSFTYELRPSGYSFWTGFRLPAAQIIPTGQETTDSLVEMIKAAAQIEGYKIE", "length": 424 }, "evidence": [ { "id": "MGI:3045348", "url": "https://alliancegenome.org/gene/MGI:3045348#orthology", "database": "AGR" }, { "id": "MGI:1891837", "url": "https://alliancegenome.org/gene/MGI:1891837#orthology", "database": "AGR" }, { "id": "MGI:88478", "url": "https://alliancegenome.org/gene/MGI:88478#orthology", "database": "AGR" }, { "id": "MGI:1921899", "url": "https://alliancegenome.org/gene/MGI:1921899#orthology", "database": "AGR" }, { "id": "MGI:88479", "url": "https://alliancegenome.org/gene/MGI:88479#orthology", "database": "AGR" }, { "id": "HGNC:2300", "url": "https://alliancegenome.org/gene/HGNC:2300#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070619-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070619-6#orthology", "database": "AGR" }, { "id": "RGD:2390", "url": "https://alliancegenome.org/gene/RGD:2390#orthology", "database": "AGR" }, { "id": "RGD:71035", "url": "https://alliancegenome.org/gene/RGD:71035#orthology", "database": "AGR" }, { "id": "RGD:1311764", "url": "https://alliancegenome.org/gene/RGD:1311764#orthology", "database": "AGR" }, { "id": "RGD:2388", "url": "https://alliancegenome.org/gene/RGD:2388#orthology", "database": "AGR" }, { "id": "SGD:S000001174", "url": "https://alliancegenome.org/gene/SGD:S000001174#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VLZ1-1", "protein_name": "Peptidase M14 domain-containing protein", "gene_name": "Dmel\\CG7025", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MALNSLPIVLALVVLAQGASFGQDERLRYDNYSVYKVKFETQAQRSILRKLAEDRENFRLWHEAKDELHLMLSPGAFGELETEIQKTNVTAELFISNVQELIDSEEAANLKASRDGTFGWTKYNSLAEIYAWLDDILAAYPTITESFIVGQSYEGRTIRGIKISYKSNNPGVLIESNIHAREWITSATATWLINEFLTSTDELVRDLAENHDWYIVPVLNVDGFVYTHEKDRMWRKTRQPSEISSCIGADPNRNYDSHWMENEGASSNPCAEDYGGPKPFSEPEIQAMSEFVISIKDKINVLLAFHSYSQLLLSPYGHTKEEFPPNFDDMMEVAKAYGDAVESLPYGTVYRYGSAAGILYPASGATIDWAYNEQGVEISYTIEFRDTGRYGFILPPVHIIPNAEEALIGIAALLEKCKDLGYLGLKSAL", "length": 429 }, "evidence": [ { "id": "MGI:3045348", "url": "https://alliancegenome.org/gene/MGI:3045348#orthology", "database": "AGR" }, { "id": "MGI:1891837", "url": "https://alliancegenome.org/gene/MGI:1891837#orthology", "database": "AGR" }, { "id": "MGI:88478", "url": "https://alliancegenome.org/gene/MGI:88478#orthology", "database": "AGR" }, { "id": "MGI:1921899", "url": "https://alliancegenome.org/gene/MGI:1921899#orthology", "database": "AGR" }, { "id": "MGI:88479", "url": "https://alliancegenome.org/gene/MGI:88479#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070619-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070619-6#orthology", "database": "AGR" }, { "id": "RGD:2390", "url": "https://alliancegenome.org/gene/RGD:2390#orthology", "database": "AGR" }, { "id": "RGD:71035", "url": "https://alliancegenome.org/gene/RGD:71035#orthology", "database": "AGR" }, { "id": "RGD:1311764", "url": "https://alliancegenome.org/gene/RGD:1311764#orthology", "database": "AGR" }, { "id": "RGD:2388", "url": "https://alliancegenome.org/gene/RGD:2388#orthology", "database": "AGR" }, { "id": "SGD:S000001174", "url": "https://alliancegenome.org/gene/SGD:S000001174#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VLZ2-1", "protein_name": "Zinc carboxypeptidase A 1", "gene_name": "Dmel\\CG18585", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRLLWLLATLVALTSAGILKDSPKERYDNFRVYKLTIQNKIQLAAIEKIGELTKKYNIWKEYDERSRQIDIMVSPGELNHFQELLKFNNISSELMIENVQERIDEEQVTPTADSATFGWTKYYELEEIEAWLDEILNAYPSVTEEFIVGKSYEGRTIRGIKISHKAGNPGIFIESNIHAREWITSASATWFINQLLTSEDADVRSLADNYDWHIIPVFNVDGFEYSHKKDRMWRKTRQPHATNACIGADANRNFDSYWLQNNGASDNPCSETFAGDNPESEPEAKALVEYLTKIQDQISVYISFHSYGQYLLSPYGHTNEEFPENYNDILTIGKAFADAIEALPYGTVYQYGSTADVLYVATGTSVDWVFNELGKKIGYTIEYRDKGRYGFILPPVQIIPNCEELMVGMLALIEKTKELGYL", "length": 422 }, "evidence": [ { "id": "MGI:3045348", "url": "https://alliancegenome.org/gene/MGI:3045348#orthology", "database": "AGR" }, { "id": "MGI:1891837", "url": "https://alliancegenome.org/gene/MGI:1891837#orthology", "database": "AGR" }, { "id": "MGI:88478", "url": "https://alliancegenome.org/gene/MGI:88478#orthology", "database": "AGR" }, { "id": "MGI:1921899", "url": "https://alliancegenome.org/gene/MGI:1921899#orthology", "database": "AGR" }, { "id": "MGI:88479", "url": "https://alliancegenome.org/gene/MGI:88479#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070619-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070619-6#orthology", "database": "AGR" }, { "id": "RGD:2390", "url": "https://alliancegenome.org/gene/RGD:2390#orthology", "database": "AGR" }, { "id": "RGD:71035", "url": "https://alliancegenome.org/gene/RGD:71035#orthology", "database": "AGR" }, { "id": "RGD:1311764", "url": "https://alliancegenome.org/gene/RGD:1311764#orthology", "database": "AGR" }, { "id": "RGD:2388", "url": "https://alliancegenome.org/gene/RGD:2388#orthology", "database": "AGR" }, { "id": "SGD:S000001174", "url": "https://alliancegenome.org/gene/SGD:S000001174#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VRZ3-1", "protein_name": "Zinc carboxypeptidase A 1", "gene_name": "Dmel\\CG14820", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLLKILLVVGLFGLARSVEQVRYDNYKVYNVRIDDLEQFKLLHTQERSLKLSSWREARHLGESSDIMLPPEYQKTFESLLTKHNFTYNLKIDNVQTHIDAQRPKQRITSMEWTQFHTLEEIYAWLDVIEDRYPDIVTPFTIGNSYEGRPIRGVKISYKEGNPAVFIESNIHAREWITSATITYFIDELLVPRNPAVRDIAQNVDWYIIPVLNTDGFAYSHEVERLWRKSRLPSDPTGECIGTDLNRNFDYLWMLTGAESDPCSQLYAGPSPESDPEISQLTAYINNSIPEGTIKIYISLHSYGQYVLSPWGHTALEFPEHYPQMMHVAKGFSDALYRRYGTVFTYGSSATTLYEVSGSGKEWAYAVKNIKIHYTIELRDKGELGFVLPPEDIIPVAREVTEGFVGMIAAAREIDIL", "length": 416 }, "evidence": [ { "id": "MGI:3045348", "url": "https://alliancegenome.org/gene/MGI:3045348#orthology", "database": "AGR" }, { "id": "MGI:1891837", "url": "https://alliancegenome.org/gene/MGI:1891837#orthology", "database": "AGR" }, { "id": "MGI:88478", "url": "https://alliancegenome.org/gene/MGI:88478#orthology", "database": "AGR" }, { "id": "MGI:1921899", "url": "https://alliancegenome.org/gene/MGI:1921899#orthology", "database": "AGR" }, { "id": "MGI:88479", "url": "https://alliancegenome.org/gene/MGI:88479#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070619-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070619-6#orthology", "database": "AGR" }, { "id": "RGD:2390", "url": "https://alliancegenome.org/gene/RGD:2390#orthology", "database": "AGR" }, { "id": "RGD:71035", "url": "https://alliancegenome.org/gene/RGD:71035#orthology", "database": "AGR" }, { "id": "RGD:1311764", "url": "https://alliancegenome.org/gene/RGD:1311764#orthology", "database": "AGR" }, { "id": "RGD:2388", "url": "https://alliancegenome.org/gene/RGD:2388#orthology", "database": "AGR" }, { "id": "SGD:S000001174", "url": "https://alliancegenome.org/gene/SGD:S000001174#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VS64-1", "protein_name": "Peptidase M14 domain-containing protein", "gene_name": "Dmel\\CG8563", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MWQGIVCSLALCLVGLAGLGIANNLAGYEGYTKYTVQHGDENAFKYMVDLQTNDAELDFWLLTRNSSVLTVSPRRKTQFEASLSSLGVSYEMQPLMELMAALQANSSFADDNYDGEYEECQQDECEQAERPRRRTRRQARGFFSHYPRYHEVLSFMSGLAARYPQFCRYESLGRSNEGRHIAALSISLNSRVRPRRVAYIQAATHGREWITTQTVLYLAYELLSNLRAFTRVLQDVEIFLVPLVNPDGYEYTHTTDRFWRKNRHRYAGHSCSGVDINRNFGNHWNYQGASQNLCSEVYSGTAPNSEPETSAVVRYLEFNRNRVKLSLDVHSFGKFIFYPYGYAKNTVPPTVGTLRSVALRAANQIGRYRGTRYTTGTSASILYEASGSLDDFAYGNLGIPLSYTLELPGDEFHVPAHDIIHVCKETFAGFIEFIRHVSLY", "length": 440 }, "evidence": [ { "id": "MGI:3045348", "url": "https://alliancegenome.org/gene/MGI:3045348#orthology", "database": "AGR" }, { "id": "MGI:1891837", "url": "https://alliancegenome.org/gene/MGI:1891837#orthology", "database": "AGR" }, { "id": "MGI:88478", "url": "https://alliancegenome.org/gene/MGI:88478#orthology", "database": "AGR" }, { "id": "MGI:1921899", "url": "https://alliancegenome.org/gene/MGI:1921899#orthology", "database": "AGR" }, { "id": "MGI:88479", "url": "https://alliancegenome.org/gene/MGI:88479#orthology", "database": "AGR" }, { "id": "HGNC:2300", "url": "https://alliancegenome.org/gene/HGNC:2300#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070619-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070619-6#orthology", "database": "AGR" }, { "id": "RGD:2390", "url": "https://alliancegenome.org/gene/RGD:2390#orthology", "database": "AGR" }, { "id": "RGD:71035", "url": "https://alliancegenome.org/gene/RGD:71035#orthology", "database": "AGR" }, { "id": "RGD:1311764", "url": "https://alliancegenome.org/gene/RGD:1311764#orthology", "database": "AGR" }, { "id": "RGD:2388", "url": "https://alliancegenome.org/gene/RGD:2388#orthology", "database": "AGR" }, { "id": "SGD:S000001174", "url": "https://alliancegenome.org/gene/SGD:S000001174#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VS65-1", "protein_name": "Peptidase M14 domain-containing protein", "gene_name": "CG18415", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRNYHLEYKVLIEDLAPLVHAQRAENLRKKLLIQWPHIDVLSAFYTHSEINDYLDSLLERFPKRVQVKQFGWSYERRPLKVLTITNGDGRRNKPVILIDGTVHAREWISPSMALYIIQQLLDNYGDNQELLQDYDWVIMPVVNADGYEYTHTDSRYWRKSRRPTSNPECIGTDINRNFGYEWGHDEGSSSDPCENIYRGERPFDQSESQVLRDVMLHYKGRLNFYLSLHSYGNYFLLPWGYTSDFPDTYQDMMSVADAGAKAIIYSTNGIYSYGSTYYVLYPTSGDTTDFAFGVVNATVAMTMELPAAGFQGFDPWISQIERLVTESWVGVRAMAAEVIRRYPS", "length": 344 }, "evidence": [ { "id": "MGI:3045348", "url": "https://alliancegenome.org/gene/MGI:3045348#orthology", "database": "AGR" }, { "id": "MGI:1891837", "url": "https://alliancegenome.org/gene/MGI:1891837#orthology", "database": "AGR" }, { "id": "MGI:88478", "url": "https://alliancegenome.org/gene/MGI:88478#orthology", "database": "AGR" }, { "id": "MGI:1921899", "url": "https://alliancegenome.org/gene/MGI:1921899#orthology", "database": "AGR" }, { "id": "MGI:88479", "url": "https://alliancegenome.org/gene/MGI:88479#orthology", "database": "AGR" }, { "id": "HGNC:2300", "url": "https://alliancegenome.org/gene/HGNC:2300#orthology", "database": "AGR" }, { "id": "RGD:2390", "url": "https://alliancegenome.org/gene/RGD:2390#orthology", "database": "AGR" }, { "id": "RGD:71035", "url": "https://alliancegenome.org/gene/RGD:71035#orthology", "database": "AGR" }, { "id": "RGD:1311764", "url": "https://alliancegenome.org/gene/RGD:1311764#orthology", "database": "AGR" }, { "id": "RGD:2388", "url": "https://alliancegenome.org/gene/RGD:2388#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VS66-1", "protein_name": "Peptidase M14 domain-containing protein", "gene_name": "Dmel\\CG8562", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKFSLGLLVLFLGATLVAAEQDYEGYRIYEVIPSTADQADLLHQLSLQGYDFISETRLLGHPSRVIVSPAQLKHFQQLVEAEKMTLTLVNSNLGASIAEEFAQRQMQRLLAPITGKGRLSTERYYTHEEIINYIDDLAQRFPSRVFVKTVGWSYEQRVLKTITITNGDGKANKKVIFMDGGFHAREWISPAAVLYVIDQLVEQFEENAHLLKDYDWVILPLVNADGYEHTQTGTLARMWRKTRQPYTYAGQTCYGADPNRNFDFHWNEEGASSNPCADTYAGPTAFSEPETITVRDLMHSLADRGIMYLTLHSYGNYLLYPWGWTSDLPENWEDLDAVARTGAEAIENATGTVYTYGSSTNVLYIAAGASDDYGYYAGFNVSITMELPGAGSIGFNPPVTRIDEFVTETWIGIRAMAEKVIEMY", "length": 424 }, "evidence": [ { "id": "MGI:3045348", "url": "https://alliancegenome.org/gene/MGI:3045348#orthology", "database": "AGR" }, { "id": "MGI:1891837", "url": "https://alliancegenome.org/gene/MGI:1891837#orthology", "database": "AGR" }, { "id": "MGI:88478", "url": "https://alliancegenome.org/gene/MGI:88478#orthology", "database": "AGR" }, { "id": "MGI:1921899", "url": "https://alliancegenome.org/gene/MGI:1921899#orthology", "database": "AGR" }, { "id": "MGI:88479", "url": "https://alliancegenome.org/gene/MGI:88479#orthology", "database": "AGR" }, { "id": "HGNC:2300", "url": "https://alliancegenome.org/gene/HGNC:2300#orthology", "database": "AGR" }, { "id": "RGD:2390", "url": "https://alliancegenome.org/gene/RGD:2390#orthology", "database": "AGR" }, { "id": "RGD:71035", "url": "https://alliancegenome.org/gene/RGD:71035#orthology", "database": "AGR" }, { "id": "RGD:1311764", "url": "https://alliancegenome.org/gene/RGD:1311764#orthology", "database": "AGR" }, { "id": "RGD:2388", "url": "https://alliancegenome.org/gene/RGD:2388#orthology", "database": "AGR" }, { "id": "SGD:S000001174", "url": "https://alliancegenome.org/gene/SGD:S000001174#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VS67-1", "protein_name": "Peptidase M14 domain-containing protein", "gene_name": "carboxypeptidase b1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTVVWVILALSCLSLSAGLQRTNKYEGYKIYEVSSEARSVAFSEALSELVKNASYYEVFSELNAGNPGKIMVHPHEQVNFVQLMEENNVKYDIINRNVGLTLSRQFETNRMLRHWFPYNGRLGTERYYNHEEINQFIEDLAGEHPRRVFLKTVGRSYEGRWLKTITITNGDARRNKNVILVDGGFHAREWISPAAATYLINQLVYNLEDNADLLLDFDWVILPVVNPDGYEYTQLSEDTRMWRKTRKPSSSDCIGTDPNRNFDFHWNEEGASDDPCDNIYAGAKPFSEPEALVVGDLIHSYVDRGQMYLTLHSYGSLILYPWGWTAAVPDTEEDLHEVAAAGQSAIQEATGTIYKIGPSATTINYAASGASDDYAFNAGFPISFTMELPFGGTGFDPPASDIDSIVKETWVGIAAMARKVIQKYPLA", "length": 427 }, "evidence": [ { "id": "MGI:3045348", "url": "https://alliancegenome.org/gene/MGI:3045348#orthology", "database": "AGR" }, { "id": "MGI:1891837", "url": "https://alliancegenome.org/gene/MGI:1891837#orthology", "database": "AGR" }, { "id": "MGI:88478", "url": "https://alliancegenome.org/gene/MGI:88478#orthology", "database": "AGR" }, { "id": "MGI:1921899", "url": "https://alliancegenome.org/gene/MGI:1921899#orthology", "database": "AGR" }, { "id": "MGI:88479", "url": "https://alliancegenome.org/gene/MGI:88479#orthology", "database": "AGR" }, { "id": "HGNC:2300", "url": "https://alliancegenome.org/gene/HGNC:2300#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070619-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070619-6#orthology", "database": "AGR" }, { "id": "RGD:2390", "url": "https://alliancegenome.org/gene/RGD:2390#orthology", "database": "AGR" }, { "id": "RGD:71035", "url": "https://alliancegenome.org/gene/RGD:71035#orthology", "database": "AGR" }, { "id": "RGD:1311764", "url": "https://alliancegenome.org/gene/RGD:1311764#orthology", "database": "AGR" }, { "id": "RGD:2388", "url": "https://alliancegenome.org/gene/RGD:2388#orthology", "database": "AGR" }, { "id": "SGD:S000001174", "url": "https://alliancegenome.org/gene/SGD:S000001174#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VS80-1", "protein_name": "Peptidase M14 domain-containing protein", "gene_name": "Dmel\\CG8539", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MWKILCGIVVLVTIVVNQLSEAREVRRRRGLMLQLDNYLSYDGIMQYLDELALSHSNRVTLKDVARTYENRALKMAIITNGDGRPGKRVIFLDAALHSREWMTPAAALLTIHKLVVEFAENSDLLTDYDWHIMPLANPDGYEYSRNTERYWRNTRTPNGGNCFGTNLNRNFAVDWNVGFPELKDPCDENYAGSSPFSEVEARTVRDIMHGLVESKRAVMYLSLHTANRSVFYPWVYDTDPVSNQKEHDEIGRFVADRILQSTGTFIKTWQYAKYAGTFGGTSMDYALLAGFPLSFVFEMSGTGRDHVEYKFFPPARDIRHLAEESWTGIKAFAEKTIEKYPPSRVISYNPMVKLAENAATRNLGFNSMVATVCLFFTYLTNCNFF", "length": 385 }, "evidence": [ { "id": "MGI:3045348", "url": "https://alliancegenome.org/gene/MGI:3045348#orthology", "database": "AGR" }, { "id": "MGI:1891837", "url": "https://alliancegenome.org/gene/MGI:1891837#orthology", "database": "AGR" }, { "id": "MGI:88478", "url": "https://alliancegenome.org/gene/MGI:88478#orthology", "database": "AGR" }, { "id": "MGI:1921899", "url": "https://alliancegenome.org/gene/MGI:1921899#orthology", "database": "AGR" }, { "id": "MGI:88479", "url": "https://alliancegenome.org/gene/MGI:88479#orthology", "database": "AGR" }, { "id": "HGNC:2300", "url": "https://alliancegenome.org/gene/HGNC:2300#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070619-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070619-6#orthology", "database": "AGR" }, { "id": "RGD:2390", "url": "https://alliancegenome.org/gene/RGD:2390#orthology", "database": "AGR" }, { "id": "RGD:71035", "url": "https://alliancegenome.org/gene/RGD:71035#orthology", "database": "AGR" }, { "id": "RGD:1311764", "url": "https://alliancegenome.org/gene/RGD:1311764#orthology", "database": "AGR" }, { "id": "RGD:2388", "url": "https://alliancegenome.org/gene/RGD:2388#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W477-1", "protein_name": "Peptidase M14 domain-containing protein", "gene_name": "CG15768", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MHRLPWKWAWLPLLLLITAKLEQVGGKTYLDWARTDSQLTRLPFFGGGVGHLLRYLHPLSMSPPSERGKISELRSELDANYVSYRGAQLWKLNFNATRGSSMAEREEDDEAAEKRQVLASPDAQFNEVVALFALTFVALIGSVFGQKLLLWRSVSVPEISGISGLPLALLTLNSSELYESTLEGLQWLSPMDLRRFDFISPGSSYQINRRYRNGSQVQRYYGFQLWKVHETRLEQPELRAFWRHFGSEVWNINQDGIDILIEQRNVADARKFMDKVGYSYNIMIDDIESAIDESYVEVPAVEHPLDSVRNNSLPWMEVPGSTMNWRRYHDQADIKQFLQTLLETYSENVELIQIGVTRNKRPLEVIRVSNGNPDNWAVFVDAGLQARDWLSPAALTYAISKLTHLWGRPKGKDKGEGQRQSRAEKAMRRIDWYFLPLANPDGYQYSRQTDRLWTKNRGYDSVSGCYGVNLDRNFDYGWDGTGSTSNPCKNLYRGAHSFSEPESRAVCSFLSGMREYLGAYVSLGGYGQAITYPWGDADYVTENQRNLKQTARRAVLALRRLNQAEYSSGTSYRQKLARPGNSADWVQDRIGPQLVFNMFLKDQGRYGYLLPPHYIVESGEEVFEFLRIIAQQLQ", "length": 634 }, "evidence": [ { "id": "MGI:3045348", "url": "https://alliancegenome.org/gene/MGI:3045348#orthology", "database": "AGR" }, { "id": "MGI:1891837", "url": "https://alliancegenome.org/gene/MGI:1891837#orthology", "database": "AGR" }, { "id": "MGI:88478", "url": "https://alliancegenome.org/gene/MGI:88478#orthology", "database": "AGR" }, { "id": "MGI:1921899", "url": "https://alliancegenome.org/gene/MGI:1921899#orthology", "database": "AGR" }, { "id": "MGI:88479", "url": "https://alliancegenome.org/gene/MGI:88479#orthology", "database": "AGR" }, { "id": "HGNC:2300", "url": "https://alliancegenome.org/gene/HGNC:2300#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070619-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070619-6#orthology", "database": "AGR" }, { "id": "RGD:2390", "url": "https://alliancegenome.org/gene/RGD:2390#orthology", "database": "AGR" }, { "id": "RGD:71035", "url": "https://alliancegenome.org/gene/RGD:71035#orthology", "database": "AGR" }, { "id": "RGD:1311764", "url": "https://alliancegenome.org/gene/RGD:1311764#orthology", "database": "AGR" }, { "id": "RGD:2388", "url": "https://alliancegenome.org/gene/RGD:2388#orthology", "database": "AGR" }, { "id": "SGD:S000001174", "url": "https://alliancegenome.org/gene/SGD:S000001174#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W478-1", "protein_name": "Peptidase M14 domain-containing protein", "gene_name": "Dmel\\CG3097", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTQKTMLLQLLLLVAAVAASLANELPSNLTLLDANEIPQRYDEAQLWRIYNISEAMQKRVPVGQMLEQKFGGNIWKENSKFLDISIARDQLKAARSFLSAHRLDPQILSHNIQSMIDEELLEGIQSSSFGHGRRTKKAARSSMHWKDYHDLETIYSFMREIRTKFPNIVRLYTIGQTAEGRDLKVLRISENPRENKKVWIDGGIHAREWISPATVTFILYQLMSDWENQPAHIRGLTWYIMPVMNPDGYEYSRTTNRLWRKNRSPSRRAQCSGVDLNRNFDIGWNGYGSSTNPCSDTYRGSAPASERETRAVAEFLAKRKYNLESYLTFHSYGQMIVYPWAYKAVKVKDASVLQRVSSLAAERILQKTGTSYRAAVTHEVLGIAGGGSDDWSRAALGVKYVYTIELRDRGAYGFVLPPRFIKDTALEGWTVVETVAQAIGPSSSG", "length": 445 }, "evidence": [ { "id": "MGI:3045348", "url": "https://alliancegenome.org/gene/MGI:3045348#orthology", "database": "AGR" }, { "id": "MGI:1891837", "url": "https://alliancegenome.org/gene/MGI:1891837#orthology", "database": "AGR" }, { "id": "MGI:88478", "url": "https://alliancegenome.org/gene/MGI:88478#orthology", "database": "AGR" }, { "id": "MGI:1921899", "url": "https://alliancegenome.org/gene/MGI:1921899#orthology", "database": "AGR" }, { "id": "MGI:88479", "url": "https://alliancegenome.org/gene/MGI:88479#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070619-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070619-6#orthology", "database": "AGR" }, { "id": "RGD:2390", "url": "https://alliancegenome.org/gene/RGD:2390#orthology", "database": "AGR" }, { "id": "RGD:71035", "url": "https://alliancegenome.org/gene/RGD:71035#orthology", "database": "AGR" }, { "id": "RGD:1311764", "url": "https://alliancegenome.org/gene/RGD:1311764#orthology", "database": "AGR" }, { "id": "RGD:2388", "url": "https://alliancegenome.org/gene/RGD:2388#orthology", "database": "AGR" }, { "id": "SGD:S000001174", "url": "https://alliancegenome.org/gene/SGD:S000001174#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit 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"start_aa": "Ala", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1123, "end_pos": 1125 }, { "start_pos": 694, "end_pos": 696 }, { "start_pos": 781, "end_pos": 783 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { 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"count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9W4G4-1", "uniprot_ac": "Q9W4G4", "uniprot_id": "Q9W4G4_DROME", "mass": { "chemical_mass": 52518.0, "monoisotopic_mass": 52518.0 }, "refseq": { "ac": "NP_572191", "name": "boilerman", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572191" }, "gene_names": [ { "name": "boil", "type": "recommended", "evidence": [ { "id": "Q9W4G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W4G4" } ] }, { "name": "CG12681", "type": "synonym", "evidence": [ { "id": "NP_572191", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572191" }, { "id": "Q9W4G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W4G4" } ] }, { "name": "Dmel\\CG12681", "type": "synonym", "evidence": [ { "id": "NP_572191", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572191" }, { "id": "Q9W4G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W4G4" } ] }, { "name": "Dmel_CG12681", "type": "synonym", "evidence": [ { "id": "Q9W4G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W4G4" } ] }, { "name": "boil", "type": "synonym", "evidence": [ { "id": "NP_572191", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572191" } ] } ], "protein_names": [ { "name": "Boilerman", "type": "synonym", "evidence": [ { "id": "Q9W4G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W4G4/entry#names_and_taxonomy" } ] }, { "name": "CG12681-PA", "type": "synonym", "evidence": [ { "id": "NP_572191", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572191" } ] }, { "name": "boil-PA", "type": "synonym", "evidence": [ { "id": "NP_572191", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572191" } ] }, { "name": "boilerman", "type": "synonym", "evidence": [ { "id": "NP_572191", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572191" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W4G4", "url": "https://www.uniprot.org/uniprotkb/Q9W4G4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "boil", "url": "https://www.uniprot.org/uniprotkb/Q9W4G4", "locus": { "chromosome": "X", "start_pos": 4877263, "end_pos": 4875670, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0029730", "url": "https://www.ensemblgenomes.org/id/FBgn0029730" } ] } } ], "crossref": [ { "id": "FB:FBgn0029730", "url": "https://alliancegenome.org/gene/FB:FBgn0029730", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0029730", "url": "https://bgee.org/?page=gene&gene_id=FBgn0029730", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0029730", "url": "https://flybase.org/reports/FBgn0029730", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "31416", "url": "https://www.ncbi.nlm.nih.gov/gene/31416", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR031732", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031732", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG12681", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG12681", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RMFYTLT", "url": "https://omabrowser.org/oma/group/RMFYTLT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W4G4", "url": "https://www.orthodb.org/?gene=Q9W4G4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF15866", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15866", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_572191", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572191", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W4G4", "url": "https://www.uniprot.org/uniprotkb/Q9W4G4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W4G4-1", "url": "https://www.uniprot.org/uniprotkb/Q9W4G4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVVPRIKKRSHSRKIEATPMDVEEKDNNRDRKHILNHLSRAPGKCILSNCNQLVFPSNMLVHMLRKHNNSPNTNLAIIYDNQRLRKTFNLNSLKYDEPQVLNILLYAGTEGKPHTRPARRYLSYPNCGLPHSFGRYEHHLMMNLMICKTSWFSMLPDRICGEKLEKMHGTPENTIYVIWLMGPETSSRMFYTLTAYDRYYIQSRSVIRKTRNFFLSQQPKDFLNHENDYLMLRHEEAMDLMNGEGDELNQTSYIKLELFLHEEPKLVSFPTHLFPTPMMSDTIRIFPLSFKAINVLPPKMMTKQNWKRAIRMSRKGPVAATKTAKESNDTSDDQEYSFDSKVKIELLKYLHSVRIPKAKRTQKQVQNEDQAKPLEMDPVLLEVPIKNRVLKTFKNAMDNSVKDAVRKVTDETLIANLDIKSELELELEIKPRNRPAEAKTEAKNETEAPQ", "length": 450, "header": "tr|Q9W4G4-1|Q9W4G4_DROME Isoform 1 of Boilerman OS=Drosophila melanogaster OX=7227 GN=boil PE=4 SV=2 CANONICAL=Q9W4G4-1" }, "isoforms": [ { "isoform_ac": "Q9W4G4-1", "url": "https://www.uniprot.org/uniprotkb/Q9W4G4/entry#Q9W4G4-1", "sequence": { "sequence": "MVVPRIKKRSHSRKIEATPMDVEEKDNNRDRKHILNHLSRAPGKCILSNCNQLVFPSNMLVHMLRKHNNSPNTNLAIIYDNQRLRKTFNLNSLKYDEPQVLNILLYAGTEGKPHTRPARRYLSYPNCGLPHSFGRYEHHLMMNLMICKTSWFSMLPDRICGEKLEKMHGTPENTIYVIWLMGPETSSRMFYTLTAYDRYYIQSRSVIRKTRNFFLSQQPKDFLNHENDYLMLRHEEAMDLMNGEGDELNQTSYIKLELFLHEEPKLVSFPTHLFPTPMMSDTIRIFPLSFKAINVLPPKMMTKQNWKRAIRMSRKGPVAATKTAKESNDTSDDQEYSFDSKVKIELLKYLHSVRIPKAKRTQKQVQNEDQAKPLEMDPVLLEVPIKNRVLKTFKNAMDNSVKDAVRKVTDETLIANLDIKSELELELEIKPRNRPAEAKTEAKNETEAPQ", "length": 450, "header": "tr|Q9W4G4-1|Q9W4G4_DROME Isoform 1 of Boilerman OS=Drosophila melanogaster OX=7227 GN=boil PE=4 SV=2 CANONICAL=Q9W4G4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W4G4", "url": "https://www.uniprot.org/uniprotkb/Q9W4G4" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W4G4", "url": "https://www.uniprot.org/uniprotkb/Q9W4G4" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W4G4", "url": "https://www.uniprot.org/uniprotkb/Q9W4G4" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W4G4", "url": 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Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W4G4", "url": "https://www.uniprot.org/uniprotkb/Q9W4G4" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W4G4", "url": "https://www.uniprot.org/uniprotkb/Q9W4G4" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi 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[ { "name": "mRpL30", "url": "https://www.uniprot.org/uniprotkb/Q9W4I3", "locus": { "chromosome": "X", "start_pos": 4648646, "end_pos": 4647871, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0029718", "url": "https://www.ensemblgenomes.org/id/FBgn0029718" } ] } } ], "crossref": [ { "id": "FB:FBgn0029718", "url": "https://alliancegenome.org/gene/FB:FBgn0029718", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0029718", "url": "https://bgee.org/?page=gene&gene_id=FBgn0029718", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00355", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00355", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0029718", "url": "https://flybase.org/reports/FBgn0029718", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "31398", "url": "https://www.ncbi.nlm.nih.gov/gene/31398", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005996", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005996", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016082", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016082", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG7038", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG7038", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TWSVRSY", "url": "https://omabrowser.org/oma/group/TWSVRSY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W4I3", "url": "https://www.orthodb.org/?gene=Q9W4I3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15892", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15892", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15892:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15892:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00327", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00327", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-5389840", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-5389840", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-5419276", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-5419276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-9937383", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9937383", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_525073", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_525073", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W4I3", "url": "https://www.uniprot.org/uniprotkb/Q9W4I3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W4I3-1", "url": "https://www.uniprot.org/uniprotkb/Q9W4I3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNLGRLLNPLRSTACSVRSYGKHNKKFLYKNGQKFEGITYYPRTPDHQDPPVEPAKLFRVQRIKPLKGNPYWENRILKDLGLDGKQSDFTVVKNIPENNARLWKIKHLIKVTPVTFPYGEPTAQDVRHTILKENGECLVTKDLGPIDTRLAARQDYDEQPKRLDTDLLRKDARLKWLNPW", "length": 180, "header": "tr|Q9W4I3-1|Q9W4I3_DROME Isoform 1 of Large ribosomal subunit protein uL30m OS=Drosophila melanogaster OX=7227 GN=mRpL30 PE=1 SV=1 CANONICAL=Q9W4I3-1" }, "isoforms": [ { "isoform_ac": "Q9W4I3-1", "url": "https://www.uniprot.org/uniprotkb/Q9W4I3/entry#Q9W4I3-1", "sequence": { "sequence": "MNLGRLLNPLRSTACSVRSYGKHNKKFLYKNGQKFEGITYYPRTPDHQDPPVEPAKLFRVQRIKPLKGNPYWENRILKDLGLDGKQSDFTVVKNIPENNARLWKIKHLIKVTPVTFPYGEPTAQDVRHTILKENGECLVTKDLGPIDTRLAARQDYDEQPKRLDTDLLRKDARLKWLNPW", "length": 180, "header": "tr|Q9W4I3-1|Q9W4I3_DROME Isoform 1 of Large ribosomal subunit protein uL30m OS=Drosophila melanogaster OX=7227 GN=mRpL30 PE=1 SV=1 CANONICAL=Q9W4I3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W4I3", "url": "https://www.uniprot.org/uniprotkb/Q9W4I3" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W4I3", "url": "https://www.uniprot.org/uniprotkb/Q9W4I3" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W4I3", "url": "https://www.uniprot.org/uniprotkb/Q9W4I3" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W4I3", "url": "https://www.uniprot.org/uniprotkb/Q9W4I3" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W4I3", "url": "https://www.uniprot.org/uniprotkb/Q9W4I3" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W4I3", "url": "https://www.uniprot.org/uniprotkb/Q9W4I3" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W4I3", "url": "https://www.uniprot.org/uniprotkb/Q9W4I3" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W4I3", "url": "https://www.uniprot.org/uniprotkb/Q9W4I3" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W4I3", "url": "https://www.uniprot.org/uniprotkb/Q9W4I3" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W4I3", "url": "https://www.uniprot.org/uniprotkb/Q9W4I3" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W4I3", "url": "https://www.uniprot.org/uniprotkb/Q9W4I3" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], 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"total": 1, "go_terms": [ { "name": "mitochondrial translation", "id": "GO:0032543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032543", "evidence": [ { "database": "UniProtKB", "id": "Q9W4I3", "url": "https://www.uniprot.org/uniprotkb/Q9W4I3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9W4I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W4I3" }, { "id": "PF00327", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00327" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Large ribosomal subunit protein uL30-like ferredoxin-like fold", "eco_id": "ECO_0000259", "start_pos": 58, "end_pos": 109, "start_aa": "Phe", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9W4J6-1", "uniprot_ac": "Q9W4J6", "uniprot_id": "Q9W4J6_DROME", "mass": { "chemical_mass": 53801.0, "monoisotopic_mass": 53801.0 }, "refseq": { "ac": "NP_572169", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572169" }, "gene_names": [ { "name": "Dmel\\CG11436", "type": "recommended", "evidence": [ { "id": "Q9W4J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W4J6" } ] }, { "name": "CG11436", "type": "synonym", "evidence": [ { "id": "NP_572169", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572169" }, { "id": "Q9W4J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W4J6" } ] }, { "name": "Dmel\\CG11436", "type": "synonym", "evidence": [ { "id": "NP_572169", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572169" } ] }, { "name": "Dmel_CG11436", "type": "synonym", "evidence": [ { "id": "Q9W4J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W4J6" } ] } ], "protein_names": [ { "name": "Tetratricopeptide repeat protein 17", "type": "recommended", "evidence": [ { "id": "Q9W4J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W4J6/entry#names_and_taxonomy" } ] }, { "name": "CG11436-PA", "type": "synonym", "evidence": [ { "id": "NP_572169", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572169" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_572169", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572169" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W4J6", "url": "https://www.uniprot.org/uniprotkb/Q9W4J6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG11436", "url": "https://www.uniprot.org/uniprotkb/Q9W4J6", "locus": { "chromosome": "X", "start_pos": 4549883, "end_pos": 4551878, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0029713", "url": "https://www.ensemblgenomes.org/id/FBgn0029713" } ] } } ], "crossref": [ { "id": "FB:FBgn0029713", "url": "https://alliancegenome.org/gene/FB:FBgn0029713", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0029713", "url": "https://bgee.org/?page=gene&gene_id=FBgn0029713", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0029713", "url": "https://flybase.org/reports/FBgn0029713", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "31386", "url": "https://www.ncbi.nlm.nih.gov/gene/31386", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052630", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052630", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG11436", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG11436", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PFFMREP", "url": "https://omabrowser.org/oma/group/PFFMREP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W4J6", "url": "https://www.orthodb.org/?gene=Q9W4J6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16091", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16091", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16091:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16091:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "NP_572169", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_572169", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W4J6", "url": "https://www.uniprot.org/uniprotkb/Q9W4J6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W4J6-1", "url": "https://www.uniprot.org/uniprotkb/Q9W4J6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRLCPLAFAVLLGLFHLIQACNHWVLREEQIVPKLDSPFHMREPHNLAAFLKQIRYSEYVERSYLDLLRKREQIVEHLRFSMRFGEDLAEQAKCAMDYYMLEKRMSYLKITPEQLKRINLPDQRQLHIQKSASSMGMEPICSDYHRLSVGPATYDHLESFRPEVLAAAFLEREHDTNVGMATVELTRRFAVDGLQHHPASWKFHTLSSYYWRMRGNAREALPCARLAALLAPPIFKDIPLLSLGTILFRMGRLADADLILTAAVEHAPNVAENHVVLASALAMKHDFNRSLQHFDEAERLDPSTLPRTQQVRNFISCLENLTKKTSKMYSYVKYMQNEVKEFKKLKHHISQNHERLIQQQLPLGARRLLGLDAKTNNDDLHRRGQYCSTRTPNGSDEPVLFCDFYSDMQMRLESKDVDIDVLERDLKANTDAVIRQVSTEIRKQFNLEQLKAAKAQMPAKATKAT", "length": 465, "header": "tr|Q9W4J6-1|Q9W4J6_DROME Isoform 1 of Tetratricopeptide repeat protein 17 OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG11436 PE=4 SV=1 CANONICAL=Q9W4J6-1" }, "isoforms": [ { "isoform_ac": "Q9W4J6-1", "url": "https://www.uniprot.org/uniprotkb/Q9W4J6/entry#Q9W4J6-1", "sequence": { "sequence": "MRLCPLAFAVLLGLFHLIQACNHWVLREEQIVPKLDSPFHMREPHNLAAFLKQIRYSEYVERSYLDLLRKREQIVEHLRFSMRFGEDLAEQAKCAMDYYMLEKRMSYLKITPEQLKRINLPDQRQLHIQKSASSMGMEPICSDYHRLSVGPATYDHLESFRPEVLAAAFLEREHDTNVGMATVELTRRFAVDGLQHHPASWKFHTLSSYYWRMRGNAREALPCARLAALLAPPIFKDIPLLSLGTILFRMGRLADADLILTAAVEHAPNVAENHVVLASALAMKHDFNRSLQHFDEAERLDPSTLPRTQQVRNFISCLENLTKKTSKMYSYVKYMQNEVKEFKKLKHHISQNHERLIQQQLPLGARRLLGLDAKTNNDDLHRRGQYCSTRTPNGSDEPVLFCDFYSDMQMRLESKDVDIDVLERDLKANTDAVIRQVSTEIRKQFNLEQLKAAKAQMPAKATKAT", "length": 465, "header": "tr|Q9W4J6-1|Q9W4J6_DROME Isoform 1 of Tetratricopeptide repeat protein 17 OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG11436 PE=4 SV=1 CANONICAL=Q9W4J6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W4J6", "url": "https://www.uniprot.org/uniprotkb/Q9W4J6" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W4J6", "url": "https://www.uniprot.org/uniprotkb/Q9W4J6" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W4J6", "url": "https://www.uniprot.org/uniprotkb/Q9W4J6" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W4J6", "url": "https://www.uniprot.org/uniprotkb/Q9W4J6" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W4J6", "url": "https://www.uniprot.org/uniprotkb/Q9W4J6" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W4J6", "url": "https://www.uniprot.org/uniprotkb/Q9W4J6" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W4J6", "url": "https://www.uniprot.org/uniprotkb/Q9W4J6" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W4J6", "url": "https://www.uniprot.org/uniprotkb/Q9W4J6" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W4J6", "url": "https://www.uniprot.org/uniprotkb/Q9W4J6" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W4J6", "url": "https://www.uniprot.org/uniprotkb/Q9W4J6" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W4J6", "url": "https://www.uniprot.org/uniprotkb/Q9W4J6" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG11436", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG11436", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B5DEL3-1", "protein_name": "Tetratricopeptide repeat protein 17", "gene_name": "Ttc17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"length": 1198 }, "evidence": [ { "id": "HGNC:25596", "url": "https://alliancegenome.org/gene/HGNC:25596#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100422-15", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100422-15#orthology", "database": "AGR" }, { "id": "MGI:1921819", "url": "https://alliancegenome.org/gene/MGI:1921819#orthology", "database": "AGR" }, { "id": "RGD:1305410", "url": "https://alliancegenome.org/gene/RGD:1305410#orthology", "database": "AGR" }, { "id": "FB:FBgn0029713", "url": "https://alliancegenome.org/gene/FB:FBgn0029713#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7F211-1", "protein_name": "Tetratricopeptide repeat protein 17", "gene_name": "ttc17", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": 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"length": 1198 }, "evidence": [ { "id": "HGNC:25596", "url": "https://alliancegenome.org/gene/HGNC:25596#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100422-15", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100422-15#orthology", "database": "AGR" }, { "id": "MGI:1921819", "url": "https://alliancegenome.org/gene/MGI:1921819#orthology", "database": "AGR" }, { "id": "RGD:1305410", "url": "https://alliancegenome.org/gene/RGD:1305410#orthology", "database": "AGR" }, { "id": "FB:FBgn0029713", "url": "https://alliancegenome.org/gene/FB:FBgn0029713#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9PVB5-1", "protein_name": "Tetratricopeptide repeat protein 17", "gene_name": "Ttc17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAIGVRGRFELLPRSGPGWLLSLSALLSVVARGALATTHWVVTEDGKIQQQVDSPMNLKHPHDLVILMRQETTVNYLKELEKQLVAQKIHIEENEDRDTGLEQRHNKEDPDCIKAKVPLGDLDLYDGTYITLESKDIRPEDFIDTESPVPPDPEQPDCTKILELPYSIHAFQHLRGVQERVNLSAPLLPKEDPIFTYLSKRLGRSIDDIGHLIHEGLQKNASSWVLYNLASFYWRIKNEPYQVVECAMRALHFSSRHNKDIALVNLANVLHRAHFSADAAVVVHAALDDSDFFTSYYTLGNIYAMLGEYNHSVLCYDHALQAKPGFEQAIKRKHAVLCQQKLEQKLEAQHRSLQRTLNELKEYQKQHDHYLRQQEILEKHKLIQEEQILRNIIHETQMAKEAQLGNHQICRLVNQQHSLHCQWDQPVRYHRGDIFENVDYVQFGDDSSTSSMMSVNFDVPTNQSDVSESVRSSPVAHSVLWVWGRDSDAYRDKQHILWPKRADCTDSYPRVPLGGELPTYFLPPENKGLRIHELTSDDYSSEEEAQPPDCSITDYRKSHTLSYLVKELEVRMDLKAKIPDDHARKILLSRIKNYTVPEEEIGSFLFHAINKPNAPVWLILNEAGLYWRAVGNSTFAIACLQRALNLAPVQYQDIPLVNLANLLIHYGLHLDATKLLLQAVAVNSSEPLTFLSLGNAYLALKNVSGALEAFRQALKLSTKCPECESSLKLIRCMQFYPFLYNATSSVCGGHCHEKPLDNSHDKQKYFAKPQSLDAAAEEPSGHGADEDPVLSVENAGRDSDALRLESTVVEESNGSDEVEKSDETKMSEEILALVDEFQQAWPLEGFGGTLEMKGRRLDLQGIRVLKKGPQDGVAKSSCYGDCRSEDDEATEWITFQVKRVKKPKGDHKKPPGKKVEASQAENGQRYQANLEITGPKVASPGPQEKKRDYQSLGWPSPDECLKLRWVELTAIVSTWLAVSSKNIDITEHIDFATPIQQPAMEPLCNGNLPTSMHTLDHLHGVSNRASLHYTGESQLTEVLQNLGKDQYPQQSLEQIGTRIAKVLEKNQTSWVLSSMAALYWRVKGQGKKAIDCLRQALHYAPHQMKDVPLISLANILHNAKLWNDAVIVATMAVEIAPHFAVNHFTLGNVYVAMEEFEKALVWYESTLKLQPEFVPAKNRIQTIQCHLMLKKGRRSP", "length": 1198 }, "evidence": [ { "id": "HGNC:25596", "url": "https://alliancegenome.org/gene/HGNC:25596#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100422-15", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100422-15#orthology", "database": "AGR" }, { "id": "MGI:1921819", "url": "https://alliancegenome.org/gene/MGI:1921819#orthology", "database": "AGR" }, { "id": "RGD:1305410", "url": "https://alliancegenome.org/gene/RGD:1305410#orthology", "database": "AGR" }, { "id": "FB:FBgn0029713", "url": "https://alliancegenome.org/gene/FB:FBgn0029713#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96AE7-1", "protein_name": "Tetratricopeptide repeat protein 17", "gene_name": "TTC17", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAVGVRGRYELPPCSGPGWLLSLSALLSVAARGAFATTHWVVTEDGKIQQQVDSPMNLKHPHDLVILMRQEATVNYLKELEKQLVAQKIHIEENEDRDTGLEQRHNKEDPDCIKAKVPLGDLDLYDGTYITLESKDISPEDYIDTESPVPPDPEQPDCTKILELPYSIHAFQHLRGVQERVNLSAPLLPKEDPIFTYLSKRLGRSIDDIGHLIHEGLQKNTSSWVLYNMASFYWRIKNEPYQVVECAMRALHFSSRHNKDIALVNLANVLHRAHFSADAAVVVHAALDDSDFFTSYYTLGNIYAMLGEYNHSVLCYDHALQARPGFEQAIKRKHAVLCQQKLEQKLEAQHRSLQRTLNELKEYQKQHDHYLRQQEILEKHKLIQEEQILRNIIHETQMAKEAQLGNHQICRLVNQQHSLHCQWDQPVRYHRGDIFENVDYVQFGEDSSTSSMMSVNFDVQSNQSDINDSVKSSPVAHSILWIWGRDSDAYRDKQHILWPKRADCTESYPRVPVGGELPTYFLPPENKGLRIHELSSDDYSTEEEAQTPDCSITDFRKSHTLSYLVKELEVRMDLKAKMPDDHARKILLSRINNYTIPEEEIGSFLFHAINKPNAPIWLILNEAGLYWRAVGNSTFAIACLQRALNLAPLQYQDVPLVNLANLLIHYGLHLDATKLLLQALAINSSEPLTFLSLGNAYLALKNISGALEAFRQALKLTTKCPECENSLKLIRCMQFYPFLYNITSSVCSGTVVEESNGSDEMENSDETKMSEEILALVDEFQQAWPLEGFGGALEMKGRRLDLQGIRVLKKGPQDGVARSSCYGDCRSEDDEATEWITFQVKRVKKPKGDHKKTPGKKVETGQIENGHRYQANLEITGPKVASPGPQGKKRDYQRLGWPSPDECLKLRWVELTAIVSTWLAVSSKNIDITEHIDFATPIQQPAMEPLCNGNLPTSMHTLDHLHGVSNRASLHYTGESQLTEVLQNLGKDQYPQQSLEQIGTRIAKVLEKNQTSWVLSSMAALYWRVKGQGKKAIDCLRQALHYAPHQMKDVPLISLANILHNAKLWNDAVIVATMAVEIAPHFAVNHFTLGNVYVAMEEFEKALVWYESTLKLQPEFVPAKNRIQTIQCHLMLKKGRRSP", "length": 1141 }, "evidence": [ { "id": "HGNC:25596", "url": "https://alliancegenome.org/gene/HGNC:25596#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100422-15", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100422-15#orthology", "database": "AGR" }, { "id": "MGI:1921819", "url": "https://alliancegenome.org/gene/MGI:1921819#orthology", "database": "AGR" }, { "id": "RGD:1305410", "url": "https://alliancegenome.org/gene/RGD:1305410#orthology", "database": "AGR" }, { "id": "FB:FBgn0029713", "url": "https://alliancegenome.org/gene/FB:FBgn0029713#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 288, "end_pos": 290, "annotation": "n_glycosylation_sequon" }, { "start_pos": 320, "end_pos": 322, "annotation": "n_glycosylation_sequon" }, { "start_pos": 393, "end_pos": 395, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 288, "end_pos": 290 }, { "start_pos": 320, "end_pos": 322 }, { "start_pos": 393, "end_pos": 395 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9W4N5-1", "uniprot_ac": "Q9W4N5", "uniprot_id": "Q9W4N5_DROME", "mass": { "chemical_mass": 65410.0, "monoisotopic_mass": 65410.0 }, "refseq": { "ac": "NP_001303565", "name": "uncharacterized protein, isoform B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001303565" }, "gene_names": [ { "name": "Dmel\\CG6414", "type": "recommended", "evidence": [ { "id": "Q9W4N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W4N5" } ] }, { "name": "CG6414", "type": "synonym", "evidence": [ { "id": "NP_001303565", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001303565" }, { "id": "Q9W4N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W4N5" } ] }, { "name": "Dmel\\CG6414", "type": "synonym", "evidence": [ { "id": "NP_001303565", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001303565" } ] }, { "name": "Dmel_CG6414", "type": "synonym", "evidence": [ { "id": "Q9W4N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W4N5" } ] } ], "protein_names": [ { "name": "Carboxylic ester hydrolase", "type": "recommended", "evidence": [ { "id": "Q9W4N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W4N5/entry#names_and_taxonomy" } ] }, { "name": "3.1.1.-", "type": "synonym", "evidence": [ { "id": "Q9W4N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W4N5/entry#names_and_taxonomy" } ] }, { "name": "CG6414-PB", "type": "synonym", "evidence": [ { "id": "NP_001303565", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001303565" } ] }, { "name": "uncharacterized protein, isoform B", "type": "synonym", "evidence": [ { "id": "NP_001303565", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001303565" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W4N5", "url": "https://www.uniprot.org/uniprotkb/Q9W4N5" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG6414", "url": "https://www.uniprot.org/uniprotkb/Q9W4N5", "locus": { "chromosome": "X", "start_pos": 3968788, "end_pos": 3971350, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0029690", "url": "https://www.ensemblgenomes.org/id/FBgn0029690" } ] } } ], "crossref": [ { "id": "FB:FBgn0029690", "url": "https://alliancegenome.org/gene/FB:FBgn0029690", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0029690", "url": "https://bgee.org/?page=gene&gene_id=FBgn0029690", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0029690", "url": "https://flybase.org/reports/FBgn0029690", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "31352", "url": "https://www.ncbi.nlm.nih.gov/gene/31352", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002018", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002018", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019819", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019819", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019826", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019826", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG6414", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG6414", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FKAGHDY", "url": "https://omabrowser.org/oma/group/FKAGHDY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W4N5", "url": "https://www.orthodb.org/?gene=Q9W4N5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43142", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43142", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43142:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43142:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00135", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00135", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-2022377", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-2022377", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-211945", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-211945", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-5578768", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-5578768", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-8964038", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8964038", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-9749641", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9749641", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001303565", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001303565", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W4N5", "url": "https://www.uniprot.org/uniprotkb/Q9W4N5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W4N5-1", "url": "https://www.uniprot.org/uniprotkb/Q9W4N5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSKDAGLWSIRVILLCICIQWSDGRNSQCLHVRLSHGGWLIGRHLTTHNGRHMRAFMGVPYAEPPLDDLRFRPPVPKAPWEGERLAIKDAPICLQRDPFRRDMILEGSEDCLYLNVYTPERPRTNGSLPVMVWFHGGGWQCGSGISSFYGPDFLLDHDIVLVSANFRLGPLGFLSTETLDCPGNNGLKDQLEVLHWVRANIASFGGDPNSVTVFGESAGGASVTYHMLSEKSRGLLHRGIAQSGTYFNPWAQPAHKGVAAGRATKLAQIVGCGNAGEWPEKLECLRKKPAEDIVASLYDMFVWDFDPMIPFPPVVEPEHDGAFLTVAPRQAAKPHGLQLPLMVGATAEEGLLKTAALLNLPQLLAEFKSQFEQVLPVVLNYDHHDDSVRQTITQRIESFYFKSGHDYDKANHQNLTDLISDGWFVAGIDEYLRLRMSQEDVAPTYVYLFDHKGAASFTEIFKGGRNEFYGACHAEELQYLFPIGRELFVSAVPTQKDLELRELMLHLWVSFAKTGNPNPTNVSFHLPNWSPASSYPVEFARLGTKMEDSASIFRLENELMQHRVDFWRDLQPHLPASHAHNEL", "length": 583, "header": "tr|Q9W4N5-1|Q9W4N5_DROME Isoform 1 of Carboxylic ester hydrolase OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG6414 PE=3 SV=2 CANONICAL=Q9W4N5-1" }, "isoforms": [ { "isoform_ac": "Q9W4N5-1", "url": "https://www.uniprot.org/uniprotkb/Q9W4N5/entry#Q9W4N5-1", "sequence": { "sequence": "MSKDAGLWSIRVILLCICIQWSDGRNSQCLHVRLSHGGWLIGRHLTTHNGRHMRAFMGVPYAEPPLDDLRFRPPVPKAPWEGERLAIKDAPICLQRDPFRRDMILEGSEDCLYLNVYTPERPRTNGSLPVMVWFHGGGWQCGSGISSFYGPDFLLDHDIVLVSANFRLGPLGFLSTETLDCPGNNGLKDQLEVLHWVRANIASFGGDPNSVTVFGESAGGASVTYHMLSEKSRGLLHRGIAQSGTYFNPWAQPAHKGVAAGRATKLAQIVGCGNAGEWPEKLECLRKKPAEDIVASLYDMFVWDFDPMIPFPPVVEPEHDGAFLTVAPRQAAKPHGLQLPLMVGATAEEGLLKTAALLNLPQLLAEFKSQFEQVLPVVLNYDHHDDSVRQTITQRIESFYFKSGHDYDKANHQNLTDLISDGWFVAGIDEYLRLRMSQEDVAPTYVYLFDHKGAASFTEIFKGGRNEFYGACHAEELQYLFPIGRELFVSAVPTQKDLELRELMLHLWVSFAKTGNPNPTNVSFHLPNWSPASSYPVEFARLGTKMEDSASIFRLENELMQHRVDFWRDLQPHLPASHAHNEL", "length": 583, "header": "tr|Q9W4N5-1|Q9W4N5_DROME Isoform 1 of Carboxylic ester hydrolase OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG6414 PE=3 SV=2 CANONICAL=Q9W4N5-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 520, "start_aa": "Thr", "end_pos": 520, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr520", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "Q9W4N5", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9W4N5" } ], "filter_code": "00000000000000001000.0000000.00000001000000.1000000.0100000000.110100100001111011.10000.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_reported_with_glycan" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W4N5", "url": "https://www.uniprot.org/uniprotkb/Q9W4N5" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W4N5", "url": "https://www.uniprot.org/uniprotkb/Q9W4N5" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W4N5", "url": "https://www.uniprot.org/uniprotkb/Q9W4N5" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W4N5", "url": "https://www.uniprot.org/uniprotkb/Q9W4N5" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W4N5", "url": "https://www.uniprot.org/uniprotkb/Q9W4N5" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W4N5", "url": "https://www.uniprot.org/uniprotkb/Q9W4N5" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W4N5", "url": "https://www.uniprot.org/uniprotkb/Q9W4N5" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W4N5", "url": "https://www.uniprot.org/uniprotkb/Q9W4N5" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W4N5", "url": "https://www.uniprot.org/uniprotkb/Q9W4N5" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W4N5", "url": "https://www.uniprot.org/uniprotkb/Q9W4N5" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W4N5", "url": "https://www.uniprot.org/uniprotkb/Q9W4N5" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] }, { "title": "Quantitative and site-specific chemoproteomic profiling of O-GlcNAcylation in Drosophila.", "journal": "Bioorganic & medicinal chemistry", "date": "2025-04-10", "authors": "Lei Cong, Chen Zihan, Hao Yi, Huang Wanping, Chu Tianyu, Xiao Kangming, Zhang Che, Zhou Wen, Li Chenjian, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9W4N5", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9W4N5" } ], "reference": [ { "type": "PubMed", "id": "40245499", "url": "https://glygen.org/publication/PubMed/40245499" } ] } ], "pathway": [ { "id": "dme:Dmel_CG6414", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG6414", "resource": "KEGG Pathway" }, { "id": "R-DME-2022377", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-2022377", "resource": "Reactome", "description": "Metabolism of Angiotensinogen to Angiotensins" }, { "id": "R-DME-211945", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-211945", "resource": "Reactome", "description": "Phase I - Functionalization of compounds" }, { "id": "R-DME-5578768", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-5578768", "resource": "Reactome", "description": "Physiological factors" }, { "id": "R-DME-8964038", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8964038", "resource": "Reactome", "description": "LDL clearance" }, { "id": "R-DME-9749641", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9749641", "resource": "Reactome", "description": "Aspirin ADME" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0B4K6L1-1", "protein_name": "Carboxylic ester hydrolase", "gene_name": "alpha-Est10", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRRYWVSLLRHFSLIPNKSVPKVFTNGDFIQQVISFKYEQRKLSTAIYSVIKTKSGPVRGVKRNTIWGGSYFSFEKIPFAKPPVGDLRFKAPEAVEPWDQELDCTSPADKPLQTHMFFRKYAGSEDCLYLNVYVKDLQPDKLRPVMVWIYGGGYQVGEASRDMYSPDFFMSKDVVIVTVAYRLGALGFLSLDDPQLNVPGNAGLKDQIMALRWVQQNIEAFGGDSNNITLFGESAGGASTHFLALSPQTEGLIHKAIVMSGSVLCPWTQPPRNNWAYRLAQKLGYTGDNKDKAIFEFLRSMSGGEIVKATATVLSNDEKHHRILFAFGPVVEPYTTEHTVVAKQPHELMQNSWSHRIPMMFGGTSFEGLLFYPEVSRRPATLDEVGNCKNLLPSDLGLNLDPKLRENYGLQLKKAYFGDEPCNQANMMKFLELCSYREFWHPIYRAALNRVRQSSAPTYLYRFDHDSKLCNAIRIVLCGHQMRGVCHGDDLCYIFHSMLSHQSAPDSPEHKVITGMVDVWTSFAAHGDPNCESIKSLKFAPIENVTNFKCLNIGDQFEVMALPELQKIEPVWNSFYAPNKL", "length": 581 }, "evidence": [ { "id": "HGNC:26741", "url": "https://alliancegenome.org/gene/HGNC:26741#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A0ABK0L778-1", "protein_name": "Carboxylic ester hydrolase", "gene_name": "Ces1e", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCLYALILVFLAAFTAGGHPSSLPVVDTLQGKVLGKYVSLEGFTQPVAVFLGVPFAKPPLGSLRFAPPQPAEPWSFVKNTTSYPPMCSQDPVAGQIVNDLLTNREENISLQFSEDCLYLNIYTPADLTKRDRLPVMVWIHGGGLVLGGASTYDGLALSTHENVVVVVIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALHWVQDNIDNFGGDPGSVTIFGESAGGESVSVLVLSPLAKNLFHKAISESGVALTAGLVKKNTRPLAEKIAVVSGCKSTTSAAMVHCLRQKTEEELLETTLKLNLFSLDLHGDSRQSYPFVPTVLDGVVLPKMPEEILAEKDFNTVPYIVGINKQEFGWILPTMMNYPPSDMKLDPMTATSLLKKSSFLLNLPEEAIPVAVEKYLRHTDDPDRNKDQLLELIGDVIFGVPSVIVSRGHRDAGARTYMYEFQYRPSFSSKMKPSTVVGDHGDEIYSVFGAPILRGGTSKEEINLSKMMMKFWANFARNGNPNGQGLPHWPEYDQKEGYLQIGATTQQAQKLKEKEVAFWSELLAMKPLHAGHTEL", "length": 561 }, "evidence": [ { "id": "RGD:621508", "url": "https://alliancegenome.org/gene/RGD:621508#orthology", "database": "AGR" }, { "id": "FB:FBgn0029690", "url": "https://alliancegenome.org/gene/FB:FBgn0029690#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A1ZA98-1", "protein_name": "Carboxylic ester hydrolase", "gene_name": "Jhe", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MIQQRMLQLLLLGQLLAGPGPFCAALATVDQLTVCPPSVGCLKGTNLQGYQSERFEAFMGIPYALPPIGDLRFSNPKVMPKLLGMYDASAPKMDCIQKNYLLPTPVVYGDEDCLYLNVYRPEIRKSALPVMVYIHGGGFFGGSAGPGVTGPEYFMDSGEVILVTMAYRLGPFGFLSTQDAVMSGNFGLKDQNLALRWVQRNIRFFGGDPQRVTIFGQSAGGVAAHMHLLSPRSHGLFHRVISMSGTANVPFAIAEQPLEQARLLAEFADVPDARNLSTVKLTKALRRINATKLLNAGDGLKYWDVDHMTNFRPVVEEGLEVDAFLNAHPMDMLAQGMPTSIPLLLGTVPGEGAVRVVNILGNETLRQSFNLRFDELLQELLEFPASFSQDRREKMMDLLVEVYFQGQHEVNELTVQGFMNLISDRGFKQPLYNTIHKNVCHTPNPVYLYSFNYQGPLSYASAYTSANVTGKYGVVHCDDLLYLFRSPLLFPDFQRNSTEAKVIHSFVDYFVHFAKFGKPRNSESLTPCSIEVLQSRPDGICDYHEFANAPDAYQGFEVHVASEFQTDRVNLWSHILNEK", "length": 579 }, "evidence": [ { "id": "HGNC:26741", "url": "https://alliancegenome.org/gene/HGNC:26741#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "D4AE76-1", "protein_name": "Carboxylic ester hydrolase", "gene_name": "Ces4a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEAGWSMKWTLDLSLTLWLVVQTALGALHTKEPLLITKHGILQGKQVHVGDTPIRVFLGVPFSQPPVGTRRFAPPEPPLPWNGIRDATTYPPSCLQESWGQITSMYLNTRKQYEWLHFSEDCLYLNVYAPVLAPGDPLLPVMVWFPGGAFLVGSASTYEGSELAARGKVVLVFLQYRLGILGFFSTGNSHARGNWGLLDQIAALRWVQENIEAFGGDPDSVTLFGQSAGAMSVSGLLMSPLAQGLFHQAISQSGTAVLKTFITHDPLKSAKKIAHLAGCDHNSTKIMVKCLKALPAEKVMLVSKKMTFFRANSHKDPKDIVWFLSPVVDGLVFPEDPVVLLTRGQVKPVPYLLGVNSAEFEWSLPFLMKLQLNQRIMNKNYITKLLWSCSILLNITEEQIPLVAREYLSDAISHHDWKMFRNHLIDLVGDATFVYATLQAARYHRDAGSPVYLYEFKHHAPGIIVKPRSDGADHGDELSYLFGSPFSKGSSRGEEKEFSLQMMKYWANFAHTGDPNDRELPYWPRFDKEEKYLQLDFDTRVGVKLREKQMTFWRRLRQPQKP", "length": 563 }, "evidence": [ { "id": "HGNC:26741", "url": "https://alliancegenome.org/gene/HGNC:26741#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5XG92-1", "protein_name": "Carboxylesterase 4A", "gene_name": "CES4A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRWILCWSLTLCLMAQTALGALHTKRPQVVTKYGTLQGKQMHVGKTPIQVFLGVPFSRPPLGILRFAPPEPPEPWKGIRDATTYPPGCLQESWGQLASMYVSTRERYKWLRFSEDCLYLNVYAPARAPGDPQLPVMVWFPGGAFIVGAASSYEGSDLAAREKVVLVFLQHRLGIFGFLSTDDSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGLMMSPLASGLFHRAISQSGTALFRLFITSNPLKVAKKVAHLAGCNHNSTQILVNCLRALSGTKVMRVSNKMRFLQLNFQRDPEEIIWSMSPVVDGVVIPDDPLVLLTQGKVSSVPYLLGVNNLEFNWLLPYIMKFPLNRQAMRKETITKMLWSTRTLLNITKEQVPLVVEEYLDNVNEHDWKMLRNRMMDIVQDATFVYATLQTAHYHRDAGLPVYLYEFEHHARGIIVKPRTDGADHGDEMYFLFGGPFATGLSMGKEKALSLQMMKYWANFARTGNPNDGNLPCWPRYNKDEKYLQLDFTTRVGMKLKEKKMAFWMSLYQSQRPEKQRQF", "length": 561 }, "evidence": [ { "id": "HGNC:26741", "url": "https://alliancegenome.org/gene/HGNC:26741#orthology", "database": "AGR" }, { "id": "FB:FBgn0029690", "url": "https://alliancegenome.org/gene/FB:FBgn0029690#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q64176-1", "protein_name": "Carboxylesterase 1E", "gene_name": "Ces1e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCLSALILVSLAAFTAGAGHPSSPPMVDTVQGKVLGKYISLEGFTQPVAVFLGVPFAKPPLGSLRFAPPQPAEPWSSVKNATSYPPMCFQDPVTGQIVNDLLTNRKEKIPLQFSEDCLYLNIYTPADLTKSDRLPVMVWIHGGGLVLGGASTYDGLVLSTHENVVVVVIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALHWVQDNIAKFGGDPGSVTIFGESAGGESVSVLVLSPLAKNLFQRAISESGVALTAGLVKKNTRPLAEKIAVISGCKNTTSAAMVHCLRQKTEEELLGTTLKLNLFKLDLHGDSRQSHPFVPTVLDGVLLPKMPEEILAEKNFNTVPYIVGINKQEFGWILPTMMNYPPSDVKLDQMTAMSLLKKSSFLLNLPEDAIAVAIEKYLRDKDYTGRNKDQLLELIGDVVFGVPSVIVSRGHRDAGAPTYMYEFQYSPSFSSEMKPDTVVGDHGDEIYSVFGAPILRGGTSEEEINLSKMMMKFWANFARNGNPNGQGLPHWPEYDQKEGYLQIGATTQQAQKLKEKEVAFWTELLAKKQLPTEHTEL", "length": 562 }, "evidence": [ { "id": "RGD:621508", "url": "https://alliancegenome.org/gene/RGD:621508#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R0W5-1", "protein_name": "Carboxylesterase 4A", "gene_name": "Ces4a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEAGWNMKWILGLSLTLCLVVQTALGALHTKEPLLITKHGILQGKQVHVGDTPIQVFLGIPFSKPPVGTRRFAPPEPPLPWNGIRDATTYPPSCLQESWGQILSMYLNTRKQYKWLHFSEDCLYLNVYAPVLAPGAPLLPVMVWFPGGAFLAGSASTYEGSELAARGKVVLVFLQYRLGILGFFSTGNSHARGNWGLLDQIAALRWVQENIEAFGGDPDSVTLFGQSAGAMSVSGLMVSPLAQGLFHQAISQSGTAVLKAFITPDPLTSAKKIAHLAGCDHNSTKVMVECLRSLSAEEVTLVSKRMSFFQANSHKDPKEIVWFLSPVVDGVVFPEDPVVLLTRGQVKPVPYLLGVNNAEFEWNLPFLMKIQLNQRMMNQTNINKILWSFNVLLNITKEQVPVVAREYLNDAISNHDWKMFRNRLIDLIGDATFVYATLQAARYHRDAGSPVYLYEFKHHASSGIIIKPYNGADHGDELSYLFGSPFSKGSSAGEEKEFSLQMMKYWANFAHTGNPNGEKLPYWPRFDKDEKYLQLDFDTRVGVKLKEKKMAFWSQLRQSQKP", "length": 563 }, "evidence": [ { "id": "HGNC:26741", "url": "https://alliancegenome.org/gene/HGNC:26741#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VLA3-1", "protein_name": "Carboxylesterase type B domain-containing protein", "gene_name": "Dmel\\CG4382", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MWRLCGFVLLLCGLASGQNSDEDLSKAIPDEEDPIGSNKELSDLVITTALGKIRGTILPSQSGRNFYAFRGIPYAKPPVDRLRFQPPEPVEQWFDTLDATFDGPKCPQLGLVSGDVSEDCLRVNIYTKELPSESQPNVRRPVIVFIHPGGFYSLSGQSKNFAGPQYFMNRRLVLVTFNYRLGSLGFLATGTREAPGNMGLKDQVQLLRWVKLHISRFGGDPSSITLLGYGAGAMAVTLHMVSPMSRGLFHKAIVMSGAVTGQWSLPDHQMDVATKQATLLHCHTENVTEMMDCLKGKHYLEFANTLPKMFEFDRNNPLILWKPVIEPDFGQERFLVEEPIRSYQNDDFMKVPIITGMTKDEFVGPALSILQSPTLLSALNENFESLAPVFFMYNTSDARACNISQELRNHYFPDKLIDANRSLEALSNLYSDALTGFGIHRFVHLAARSTKVYYYRFSYQGARSHIYYPEDAPYGVVHHDDLMYLFVEPSISRMFTEDDDEFRMVDIMVRMFSAFAYKGDPNKPTDLALRDIRWRPFSFKKRYYLDIGKHITLEENLNAENYEIWKRLFPLNWRRQTKEV", "length": 580 }, "evidence": [ { "id": "HGNC:26741", "url": "https://alliancegenome.org/gene/HGNC:26741#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q9W4N5", "url": "https://www.uniprot.org/uniprotkb/Q9W4N5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "carboxylesterase activity", "id": "GO:0106435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106435", "evidence": [ { "database": "UniProtKB", "id": "Q9W4N5", "url": "https://www.uniprot.org/uniprotkb/Q9W4N5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 125, "end_pos": 127, "annotation": "n_glycosylation_sequon" }, { "start_pos": 414, "end_pos": 416, "annotation": "n_glycosylation_sequon" }, { "start_pos": 521, "end_pos": 523, "annotation": "n_glycosylation_sequon" }, { "start_pos": 528, "end_pos": 530, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-DME-5693691", "name": "CES1 trimer.CES2 hydrolyse COCN to BEG", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endoplasmic reticulum lumen", "input_participant_list": [ "R-ALL-5693702" ], "output_participant_list": [ "R-ALL-5693711", "R-ALL-5693712" ], "enzyme_list": [ "A1ZA98-1", "A0A0B4LHM3-1", "Q9W2F4-1", "A1ZA97-1", "Q9W4N5-1", "Q9Y141-1" ], "evidence": [ { "id": "R-DME-5693691", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-5693691" } ] }, { "id": "R-DME-8937442", "name": "CES3 hydrolyses CHEST to CHOL and LCFA(-)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, lipid droplet, transport vesicle membrane", "input_participant_list": [ "R-ALL-163579" ], "output_participant_list": [], "enzyme_list": [ "A1ZA98-1", "A0A0B4LHM3-1", "Q9W2F4-1", "A1ZA97-1", "Q9W4N5-1", "Q9Y141-1" ], "evidence": [ { "id": "R-DME-8937442", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8937442" } ] }, { "id": "R-DME-9619024", "name": "CES1 trimer hydrolyses ACEI pro-drugs to ACEIs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region", "input_participant_list": [], "output_participant_list": [ "R-ALL-140972" ], "enzyme_list": [ "A1ZA98-1", "A0A0B4LHM3-1", "Q9W2F4-1", "A1ZA97-1", "Q9W4N5-1", "Q9Y141-1" ], "evidence": [ { "id": "R-DME-9619024", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9619024" } ] }, { "id": "R-DME-9727567", "name": "CES1 hydrolyses sacubitril to sacubitrilat", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, lipid droplet", "input_participant_list": [ "R-ALL-9727597" ], "output_participant_list": [ "R-ALL-9727588" ], "enzyme_list": [ "A1ZA98-1", "A0A0B4LHM3-1", "Q9W2F4-1", "A1ZA97-1", "Q9W4N5-1", "Q9Y141-1" ], "evidence": [ { "id": "R-DME-9727567", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9727567" } ] }, { "id": "R-DME-9749647", "name": "CES2 hydrolyzes ASA-", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endoplasmic reticulum lumen", "input_participant_list": [ "R-ALL-9749582" ], "output_participant_list": [ "R-ALL-9749588", "R-ALL-9749593" ], "enzyme_list": [ "A1ZA98-1", "A0A0B4LHM3-1", "Q9W2F4-1", "A1ZA97-1", "Q9W4N5-1", "Q9Y141-1" ], "evidence": [ { "id": "R-DME-9749647", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9749647" } ] }, { "id": "R-DME-9749792", "name": "CES1,CES2 hydrolyze ASA- to ST", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endoplasmic reticulum lumen", "input_participant_list": [ "R-ALL-9749795" ], "output_participant_list": [ "R-ALL-9749790" ], "enzyme_list": [ "A1ZA98-1", "A0A0B4LHM3-1", "Q9W2F4-1", "A1ZA97-1", "Q9W4N5-1", "Q9Y141-1" ], "evidence": [ { "id": "R-DME-9749792", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9749792" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-140972", "participant_name": "Alcohol [endoplasmic reticulum lumen]", "crossref": [ { "id": "C00069", "database": "COMPOUND", "url": "" }, { "id": "30879", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-163579", "participant_name": "CHEST [lipid droplet]", "crossref": [ { "id": "17002", "database": "ChEBI", "url": "" }, { "id": "C02530", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-5693702", "participant_name": "COCN [endoplasmic reticulum lumen]", "crossref": [ { "id": "27958", "database": "ChEBI", "url": "" }, { "id": "C01416", "database": "COMPOUND", "url": "" }, { "id": "2286", "database": "Guide to Pharmacology - Ligands", "url": "" }, { "id": "ZINC000003875336", "database": "ZINC", "url": "" }, { "id": "HMDB0015043", "database": "HMDB Metabolite", "url": "" } ] }, { "participant_id": "R-ALL-5693711", "participant_name": "MeOH [endoplasmic reticulum lumen]", "crossref": [ { "id": "17790", "database": "ChEBI", "url": "" }, { "id": "HMDB0001875", "database": "HMDB Metabolite", "url": "" }, { "id": "C00132", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-5693712", "participant_name": "BEG [endoplasmic reticulum lumen]", "crossref": [ { "id": "ZINC000002572652", "database": "ZINC", "url": "" }, { "id": "41001", "database": "ChEBI", "url": "" }, { "id": "C10847", "database": "COMPOUND", "url": "" }, { "id": "HMDB0041836", "database": "HMDB Metabolite", "url": "" } ] }, { "participant_id": "R-ALL-9727588", "participant_name": "sacubitrilat [cytosol]", "crossref": [ { "id": "7858", "database": "Guide to Pharmacology - Ligands", "url": "" }, { "id": "0005009", "database": "Mondo", "url": "" } ] }, { "participant_id": "R-ALL-9727597", "participant_name": "sacubitril [cytosol]", "crossref": [ { "id": "7857", "database": "Guide to Pharmacology - Ligands", "url": "" }, { "id": "134714", "database": "ChEBI", "url": "" }, { "id": "0005009", "database": "Mondo", "url": "" } ] }, { "participant_id": "R-ALL-9749582", "participant_name": "ASA- (GI cell) [endoplasmic reticulum lumen]", "crossref": [ { "id": "13719", "database": "ChEBI", "url": "" }, { "id": "ZINC000000000053", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-9749588", "participant_name": "acetate [endoplasmic reticulum lumen]", "crossref": [ { "id": "30089", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-9749593", "participant_name": "ST (GI cell) [endoplasmic reticulum lumen]", "crossref": [ { "id": "30762", "database": "ChEBI", "url": "" }, { "id": "ZINC000000001554", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-9749790", "participant_name": "ST (hepatocyte) [endoplasmic reticulum lumen]", "crossref": [ { "id": "ZINC000000001554", "database": "ZINC", "url": "" }, { "id": "30762", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-9749795", "participant_name": "ASA- (hepatocyte) [endoplasmic reticulum lumen]", "crossref": [ { "id": "13719", "database": "ChEBI", "url": "" }, { "id": "ZINC000000000053", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A0B4LHM3", "gene_name": "Est17", "activity": [ { "ec_number": "3.1.1.1", "activity": "a carboxylic ester + H2O = an alcohol + a carboxylate + H(+).", "evidence": [ { "id": "A0A0B4LHM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHM3" } ] }, { "ec_number": "3.1.1.1", "activity": "", "evidence": [ { "id": "A0A0B4LHM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHM3" } ] }, { "ec_number": "3.1.1.-", "activity": "", "evidence": [ { "id": "A0A0B4LHM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0B4LHM3" } ] } ] }, { "uniprot_ac": "A1ZA97", "gene_name": "Jhedup", "activity": [ { "ec_number": "3.1.1.-", "activity": "", "evidence": [ { "id": "A1ZA97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1ZA97" } ] } ] }, { "uniprot_ac": "A1ZA98", "gene_name": "Jhe", "activity": [ { "ec_number": "3.1.1.-", "activity": "", "evidence": [ { "id": "A1ZA98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1ZA98" } ] } ] }, { "uniprot_ac": "Q9W2F4", "gene_name": "clt", "activity": [ { "ec_number": "3.1.1.1", "activity": "a carboxylic ester + H2O = an alcohol + a carboxylate + H(+).", "evidence": [ { "id": "Q9W2F4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W2F4" } ] }, { "ec_number": "3.1.1.1", "activity": "", "evidence": [ { "id": "Q9W2F4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W2F4" } ] } ] }, { "uniprot_ac": "Q9W4N5", "gene_name": "Dmel\\CG6414", "activity": [ { "ec_number": "3.1.1.-", "activity": "", "evidence": [ { "id": "Q9W4N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W4N5" } ] } ] }, { "uniprot_ac": "Q9Y141", "gene_name": "GH05741", "activity": [ { "ec_number": "3.1.1.-", "activity": "", "evidence": [ { "id": "Q9Y141", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9Y141" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9W4N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W4N5" }, { "id": "PF00135", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00135" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Carboxylesterase type B", "eco_id": "ECO_0000259", "start_pos": 32, 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"https://www.ebi.ac.uk/interpro/entry/IPR036152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG6428", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG6428", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CDVGVIP", "url": "https://omabrowser.org/oma/group/CDVGVIP/", "database": "OMA", "categories": [ "Protein 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"https://www.reactome.org/PathwayBrowser/#R-DME-8963693", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_570088", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_570088", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W4N6", "url": "https://www.uniprot.org/uniprotkb/Q9W4N6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W4N6-1", "url": "https://www.uniprot.org/uniprotkb/Q9W4N6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDIPVLKTNGHERLASLDKSMPPASPTLPSPTIRRNKSDGKLMAQDVKEARVKVIYTGGTIGMVRNERNVLAPIPNALVRSIRKYPNIHDEEYALRRFGASASMAPLVLPIVQGVDRRVIYQISEYTPLLDSSNMTMNDWARIASDIQQSYEFFDGFVVLHGTDTLSYTASALSFMLENLGKTVIITGSQIPIFETRTDGKDNFTSALIIAGNYIIPEVCIFFGHKLMRGNRTVKVSSNALDAFDSPNVPPLARIGIDVNVDYRLIFRPCTIERFCVHLNLDENVGLLRIFPSISHSTFRAFLAPPIRGVVLQSFGSGNIPSNRKDLIDELRAAGERGVIIINCTQCPNGTVAEIYDTGKVLCDVGVIPGFDMTPEAALAKLAYVIGKEEWSLDMKKQMMQSSLRGELTSLKAPKMEDYDLVDAVARSLHLSSPQELDQLGETLFPAMINAAVAEGDPKKINNLKAYGADLSGTNHDQRTALHLACQLGNVEIVKYLLQNGVSVHVRDRYDRTPLLEAVATDSHEIIQLLINCGAHLTGSSRAVGEQLCAAAARGSMIRLKSYQYAGADLAQSDPSGRTALHVAALHGFPEVVQYVLPYFENPNEKDMLGLTAMDYAERGGHAAVMEVLKS", "length": 631, "header": "tr|Q9W4N6-1|Q9W4N6_DROME Isoform 1 of asparaginase OS=Drosophila melanogaster OX=7227 GN=CG-6428 PE=1 SV=1 CANONICAL=Q9W4N6-1" }, "isoforms": [ { "isoform_ac": "Q9W4N6-1", "url": "https://www.uniprot.org/uniprotkb/Q9W4N6/entry#Q9W4N6-1", "sequence": { "sequence": "MDIPVLKTNGHERLASLDKSMPPASPTLPSPTIRRNKSDGKLMAQDVKEARVKVIYTGGTIGMVRNERNVLAPIPNALVRSIRKYPNIHDEEYALRRFGASASMAPLVLPIVQGVDRRVIYQISEYTPLLDSSNMTMNDWARIASDIQQSYEFFDGFVVLHGTDTLSYTASALSFMLENLGKTVIITGSQIPIFETRTDGKDNFTSALIIAGNYIIPEVCIFFGHKLMRGNRTVKVSSNALDAFDSPNVPPLARIGIDVNVDYRLIFRPCTIERFCVHLNLDENVGLLRIFPSISHSTFRAFLAPPIRGVVLQSFGSGNIPSNRKDLIDELRAAGERGVIIINCTQCPNGTVAEIYDTGKVLCDVGVIPGFDMTPEAALAKLAYVIGKEEWSLDMKKQMMQSSLRGELTSLKAPKMEDYDLVDAVARSLHLSSPQELDQLGETLFPAMINAAVAEGDPKKINNLKAYGADLSGTNHDQRTALHLACQLGNVEIVKYLLQNGVSVHVRDRYDRTPLLEAVATDSHEIIQLLINCGAHLTGSSRAVGEQLCAAAARGSMIRLKSYQYAGADLAQSDPSGRTALHVAALHGFPEVVQYVLPYFENPNEKDMLGLTAMDYAERGGHAAVMEVLKS", "length": 631, "header": "tr|Q9W4N6-1|Q9W4N6_DROME Isoform 1 of asparaginase OS=Drosophila melanogaster OX=7227 GN=CG-6428 PE=1 SV=1 CANONICAL=Q9W4N6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W4N6", "url": "https://www.uniprot.org/uniprotkb/Q9W4N6" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W4N6", "url": "https://www.uniprot.org/uniprotkb/Q9W4N6" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W4N6", "url": "https://www.uniprot.org/uniprotkb/Q9W4N6" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W4N6", "url": "https://www.uniprot.org/uniprotkb/Q9W4N6" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W4N6", "url": "https://www.uniprot.org/uniprotkb/Q9W4N6" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W4N6", "url": "https://www.uniprot.org/uniprotkb/Q9W4N6" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W4N6", "url": "https://www.uniprot.org/uniprotkb/Q9W4N6" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W4N6", "url": "https://www.uniprot.org/uniprotkb/Q9W4N6" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W4N6", "url": "https://www.uniprot.org/uniprotkb/Q9W4N6" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W4N6", "url": "https://www.uniprot.org/uniprotkb/Q9W4N6" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W4N6", "url": "https://www.uniprot.org/uniprotkb/Q9W4N6" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG6428", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG6428", "resource": "KEGG Pathway" }, { "id": "R-DME-8963693", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8963693", "resource": "Reactome", "description": "Aspartate and asparagine metabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M9P006-1", "protein_name": "asparaginase", "gene_name": "aspg", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEWKHNTSAPSSASMTSLCRALSRSKLNQSDTFQSQKSLSRSAAGQSRRRFSSSSESPPDVSPNVEARVLVINTGGTIGMTYHNNVLSPEPNAFVETLRKLPILHDEQYAQHTRLYDYYKPQENTLVLPRSTHTADPLFHGLSKQNKRIVYTVLEYSPLLDSCNMTTDDWATIGKDIEKHYEQYDGFVILHGTDTMAYTASALSFMCENLGKPVILTGSQVPIYEMRNDGRDNLLGALLIAGQFVIPEVCLYFHHKLYRGNRVTKVDAGSFNAFNSPNLPPLANAEVDIKINWDTVWRANTTAKFTVNTQMNRNVGLLRLFPGITADTVRAFLQPPMDGIVLETYGSGNAPDNRADLLDEIRKATQRGLIMINCTQCLRGSVTTSYATGQALSDAGLVAGCDMTPEAALSKLSYVLAKQNLSIEEKKKMLSHNLRGEMIADVGGAKLSLSDSRFIQVIAKSLSISCKEELEAIRDALTPTLVCVAAKIGDIDALEAIREMGTDLSMADYDGRTPLHIAACEGHLKVVEYLLGKGATVYAKDRFGHTPLRNAVRFRHKDVVKLLRKTGAHFSREEMADTGTELCSLAAAGDLEGLEIWQLAGVDLTMTSYDGQTPIEVARATGCVESVEFLKQAALYQTQHQADEGNEPVFEEDEDENGEYIEFTAAPRS", "length": 670 }, "evidence": [ { "id": "RGD:708388", "url": "https://alliancegenome.org/gene/RGD:708388#orthology", "database": "AGR" }, { "id": "MGI:2144822", "url": "https://alliancegenome.org/gene/MGI:2144822#orthology", "database": "AGR" }, { "id": "HGNC:20123", "url": "https://alliancegenome.org/gene/HGNC:20123#orthology", "database": "AGR" }, { "id": "FB:FBgn0029689", "url": "https://alliancegenome.org/gene/FB:FBgn0029689#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070820-14", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070820-14#orthology", "database": "AGR" }, { "id": "SGD:S000004150", "url": "https://alliancegenome.org/gene/SGD:S000004150#orthology", "database": "AGR" }, { "id": "SGD:S000004145", "url": "https://alliancegenome.org/gene/SGD:S000004145#orthology", "database": "AGR" }, { "id": "SGD:S000004147", "url": "https://alliancegenome.org/gene/SGD:S000004147#orthology", "database": "AGR" }, { "id": "SGD:S000004148", "url": "https://alliancegenome.org/gene/SGD:S000004148#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0JNU3-1", "protein_name": "60 kDa lysophospholipase", "gene_name": "Aspg", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARAMGPERRLLAIYTGGTIGMRSEGGVLVPGRGLAAVLKTLHMFHDEEYAQAHSLPEDTLVLPPASPDQRIIYTVLECQPLFDSSDMTITEWVQIAQTIERHYAQYQGFVVIHGTDTMAFAASVLSFMLENLQKPVVLTGAQVPIHALWSDGRENLLGALLMAGQYVIPEVCLFFQNQLFRGNRTTKVDARRFAAFCSPNLPPLATVGADVTINRELVRKACGKSHLVVHSSMEPDVGLLRLYPGIPASLVRTFLQPPLKGVVMETFGSGNGPTKPDLLQELRVAAEQGLIIVNCTHCLQGAVTSDYASGMAMAGAGIVSGFDMTSEAALAKLSYVLGQPGLSLNDRKKLLAKDLRGEMTLPATDVLLQDGMLGCRVAWLLSMNGSQEADTMKDVLLPGLALAAAHAGDLDTLQAFVELDRDLNLKDYSGQTPLHVAARRGHAAVVTMLLQRGADVDARNEDGQSPLLLAVRGRHQSVIGLLRAAGARLSPQELEDVGTELCRLASRGDSEGLRAWWQAGADLGQPDYDGHCALQVAEAAGNADVVALLQSFKDSVCAQPQPH", "length": 564 }, "evidence": [ { "id": "RGD:708388", "url": "https://alliancegenome.org/gene/RGD:708388#orthology", "database": "AGR" }, { "id": "MGI:2144822", "url": "https://alliancegenome.org/gene/MGI:2144822#orthology", "database": "AGR" }, { "id": "HGNC:20123", "url": "https://alliancegenome.org/gene/HGNC:20123#orthology", "database": "AGR" }, { "id": "FB:FBgn0029689", "url": "https://alliancegenome.org/gene/FB:FBgn0029689#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070820-14", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070820-14#orthology", "database": "AGR" }, { "id": "SGD:S000004150", "url": "https://alliancegenome.org/gene/SGD:S000004150#orthology", "database": "AGR" }, { "id": "SGD:S000004145", "url": "https://alliancegenome.org/gene/SGD:S000004145#orthology", "database": "AGR" }, { "id": "SGD:S000004147", "url": "https://alliancegenome.org/gene/SGD:S000004147#orthology", "database": "AGR" }, { "id": "SGD:S000004148", "url": "https://alliancegenome.org/gene/SGD:S000004148#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O88202-1", "protein_name": "60 kDa lysophospholipase", "gene_name": "Aspg", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARATGPEQRLLAIYTGGTIGMRSEGGVLVPGRGLAAVLRTLHMLHDEEYARAHSLPEDTLVLPPASSDQRIIYKVLECQPLFDSSDMTITEWVQIAQTIERHYTQYQGFVVIHGTDTMAFAASVLSFMLENLQKPVILTGAQVPIHELWSDGRENLLGALLMAGQYVIPEVCLFFQNQLFRGNRTTKVDARRFAAFCSPNLPPLATVGADVTINRELVRKASWKSHLVVHSNMEPDVGLLRLYPGIPASLVRTFLQPPLKGVVMETFGSGNGPTKPDLIQELRAAAERGLIIVNCTHCLQGAVTSDYAPGMAMAGAGIISGFDMTSEAALAKLSYVLGQPGLSLSDRKKLLAKDLRGEMTLPTTDDLLGDDMLGCRATWLLSMNGSQDADAMKDVLLPGLALAAAHAGDLDTLQAFVELGRDLNLKDYSGQTPLHVAARRGHASVVAMLLQKGVDVDACNEDGQSPLLLAVRGRHQSVIRLLRAAGAHLSPQELEDVGTELCRLASRADSEGLRAWWQAGADLGQPDYDGHCALQVAEAAGNADVVALLQSLEDRVSAQPQPH", "length": 564 }, "evidence": [ { "id": "RGD:708388", "url": "https://alliancegenome.org/gene/RGD:708388#orthology", "database": "AGR" }, { "id": "MGI:2144822", "url": "https://alliancegenome.org/gene/MGI:2144822#orthology", "database": "AGR" }, { "id": "HGNC:20123", "url": "https://alliancegenome.org/gene/HGNC:20123#orthology", "database": "AGR" }, { "id": "FB:FBgn0029689", "url": "https://alliancegenome.org/gene/FB:FBgn0029689#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070820-14", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070820-14#orthology", "database": "AGR" }, { "id": "SGD:S000004150", "url": "https://alliancegenome.org/gene/SGD:S000004150#orthology", "database": "AGR" }, { "id": "SGD:S000004145", "url": "https://alliancegenome.org/gene/SGD:S000004145#orthology", "database": "AGR" }, { "id": "SGD:S000004147", "url": "https://alliancegenome.org/gene/SGD:S000004147#orthology", "database": "AGR" }, { "id": "SGD:S000004148", "url": "https://alliancegenome.org/gene/SGD:S000004148#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0CX77-1", "protein_name": "L-asparaginase 2-2", "gene_name": "ASP3-2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MRSLNTLLLSLFVAMSSGAPLLKIREEKNSSLPSIKIFGTGGTIASKGSTSATTAGYSVGLTVNDLIEAVPSLAEKANLDYLQVSNVGSNSLNYTHLIPLYHGISEALASDDYAGAVVTHGTDTMEETAFFLDLTINSEKPVCIAGAMRPATATSADGPMNLYQAVSIAASEKSLGRGTMITLNDRIASGFWTTKMNANSLDTFRADEQGYLGYFSNDDVEFYYPPVKPNGWQFFDISNLTDPSEIPEVIILYSYQGLNPELIVKAVKDLGAKGIVLAGSGAGSWTATGSIVNEQLYEEYGIPIVHSRRTADGTVPPDDAPEYAIGSGYLNPQKSRILLQLCLYSGYGMDQIRSVFSGVYGG", "length": 362 }, "evidence": [ { "id": "RGD:708388", "url": "https://alliancegenome.org/gene/RGD:708388#orthology", "database": "AGR" }, { "id": "MGI:2144822", "url": "https://alliancegenome.org/gene/MGI:2144822#orthology", "database": "AGR" }, { "id": "HGNC:20123", "url": "https://alliancegenome.org/gene/HGNC:20123#orthology", "database": "AGR" }, { "id": "FB:FBgn0029689", "url": "https://alliancegenome.org/gene/FB:FBgn0029689#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070820-14", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070820-14#orthology", "database": "AGR" }, { "id": "SGD:S000004147", "url": "https://alliancegenome.org/gene/SGD:S000004147#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P0CX78-1", "protein_name": "L-asparaginase 2-3", "gene_name": "ASP3-3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MRSLNTLLLSLFVAMSSGAPLLKIREEKNSSLPSIKIFGTGGTIASKGSTSATTAGYSVGLTVNDLIEAVPSLAEKANLDYLQVSNVGSNSLNYTHLIPLYHGISEALASDDYAGAVVTHGTDTMEETAFFLDLTINSEKPVCIAGAMRPATATSADGPMNLYQAVSIAASEKSLGRGTMITLNDRIASGFWTTKMNANSLDTFRADEQGYLGYFSNDDVEFYYPPVKPNGWQFFDISNLTDPSEIPEVIILYSYQGLNPELIVKAVKDLGAKGIVLAGSGAGSWTATGSIVNEQLYEEYGIPIVHSRRTADGTVPPDDAPEYAIGSGYLNPQKSRILLQLCLYSGYGMDQIRSVFSGVYGG", "length": 362 }, "evidence": [ { "id": "RGD:708388", "url": "https://alliancegenome.org/gene/RGD:708388#orthology", "database": "AGR" }, { "id": "MGI:2144822", "url": "https://alliancegenome.org/gene/MGI:2144822#orthology", "database": "AGR" }, { "id": "HGNC:20123", "url": "https://alliancegenome.org/gene/HGNC:20123#orthology", "database": "AGR" }, { "id": "FB:FBgn0029689", "url": "https://alliancegenome.org/gene/FB:FBgn0029689#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070820-14", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070820-14#orthology", "database": "AGR" }, { "id": "SGD:S000004148", "url": "https://alliancegenome.org/gene/SGD:S000004148#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P0CX79-1", "protein_name": "L-asparaginase 2-4", "gene_name": "ASP3-4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MRSLNTLLLSLFVAMSSGAPLLKIREEKNSSLPSIKIFGTGGTIASKGSTSATTAGYSVGLTVNDLIEAVPSLAEKANLDYLQVSNVGSNSLNYTHLIPLYHGISEALASDDYAGAVVTHGTDTMEETAFFLDLTINSEKPVCIAGAMRPATATSADGPMNLYQAVSIAASEKSLGRGTMITLNDRIASGFWTTKMNANSLDTFRADEQGYLGYFSNDDVEFYYPPVKPNGWQFFDISNLTDPSEIPEVIILYSYQGLNPELIVKAVKDLGAKGIVLAGSGAGSWTATGSIVNEQLYEEYGIPIVHSRRTADGTVPPDDAPEYAIGSGYLNPQKSRILLQLCLYSGYGMDQIRSVFSGVYGG", "length": 362 }, "evidence": [ { "id": "RGD:708388", "url": "https://alliancegenome.org/gene/RGD:708388#orthology", "database": "AGR" }, { "id": "MGI:2144822", "url": "https://alliancegenome.org/gene/MGI:2144822#orthology", "database": "AGR" }, { "id": "HGNC:20123", "url": "https://alliancegenome.org/gene/HGNC:20123#orthology", "database": "AGR" }, { "id": "FB:FBgn0029689", "url": "https://alliancegenome.org/gene/FB:FBgn0029689#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070820-14", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070820-14#orthology", "database": "AGR" }, { "id": "SGD:S000004150", "url": "https://alliancegenome.org/gene/SGD:S000004150#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P0CZ17-1", "protein_name": "L-asparaginase 2-1", "gene_name": "ASP3-1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MRSLNTLLLSLFVAMSSGAPLLKIREEKNSSLPSIKIFGTGGTIASKGSTSATTAGYSVGLTVNDLIEAVPSLAEKANLDYLQVSNVGSNSLNYTHLIPLYHGISEALASDDYAGAVVTHGTDTMEETAFFLDLTINSEKPVCIAGAMRPATATSADGPMNLYQAVSIAASEKSLGRGTMITLNDRIASGFWTTKMNANSLDTFRADEQGYLGYFSNDDVEFYYPPVKPNGWQFFDISNLTDPSEIPEVIILYSYQGLNPELIVKAVKDLGAKGIVLAGSGAGSWTATGSIVNEQLYEEYGIPIVHSRRTADGTVPPDDAPEYAIGSGYLNPQKSRILLQLCLYSGYGMDQIRSVFSGVYGG", "length": 362 }, "evidence": [ { "id": "RGD:708388", "url": "https://alliancegenome.org/gene/RGD:708388#orthology", "database": "AGR" }, { "id": "MGI:2144822", "url": "https://alliancegenome.org/gene/MGI:2144822#orthology", "database": "AGR" }, { "id": "HGNC:20123", "url": "https://alliancegenome.org/gene/HGNC:20123#orthology", "database": "AGR" }, { "id": "FB:FBgn0029689", "url": "https://alliancegenome.org/gene/FB:FBgn0029689#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070820-14", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070820-14#orthology", "database": "AGR" }, { "id": "SGD:S000004145", "url": "https://alliancegenome.org/gene/SGD:S000004145#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q86U10-1", "protein_name": "60 kDa lysophospholipase", "gene_name": "ASPG", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARAVGPERRLLAVYTGGTIGMRSELGVLVPGTGLAAILRTLPMFHDEEHARARGLSEDTLVLPPASRNQRILYTVLECQPLFDSSDMTIAEWVCLAQTIKRHYEQYHGFVVIHGTDTMAFAASMLSFMLENLQKTVILTGAQVPIHALWSDGRENLLGALLMAGQYVIPEVCLFFQNQLFRGNRATKVDARRFAAFCSPNLLPLATVGADITINRELVRKVDGKAGLVVHSSMEQDVGLLRLYPGIPAALVRAFLQPPLKGVVMETFGSGNGPTKPDLLQELRVATERGLVIVNCTHCLQGAVTTDYAAGMAMAGAGVISGFDMTSEAALAKLSYVLGQPGLSLDVRKELLTKDLRGEMTPPSVEERRPSLQGNTLGGGVSWLLSLSGSQEADALRNALVPSLACAAAHAGDVEALQALVELGSDLGLVDFNGQTPLHAAARGGHTEAVTMLLQRGVDVNTRDTDGFSPLLLAVRGRHPGVIGLLREAGASLSTQELEEAGTELCRLAYRADLEGLQVWWQAGADLGQPGYDGHSALHVAEAAGNLAVVAFLQSLEGAVGAQAPCPEVLPGV", "length": 573 }, "evidence": [ { "id": "RGD:708388", "url": "https://alliancegenome.org/gene/RGD:708388#orthology", "database": "AGR" }, { "id": "MGI:2144822", "url": "https://alliancegenome.org/gene/MGI:2144822#orthology", "database": "AGR" }, { "id": "HGNC:20123", "url": "https://alliancegenome.org/gene/HGNC:20123#orthology", "database": "AGR" }, { "id": "FB:FBgn0029689", "url": "https://alliancegenome.org/gene/FB:FBgn0029689#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070820-14", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070820-14#orthology", "database": "AGR" }, { "id": "SGD:S000004150", "url": "https://alliancegenome.org/gene/SGD:S000004150#orthology", "database": "AGR" }, { "id": "SGD:S000004145", "url": "https://alliancegenome.org/gene/SGD:S000004145#orthology", "database": "AGR" }, { "id": "SGD:S000004147", "url": "https://alliancegenome.org/gene/SGD:S000004147#orthology", "database": "AGR" }, { "id": "SGD:S000004148", "url": "https://alliancegenome.org/gene/SGD:S000004148#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VH61-1", "protein_name": "asparaginase", "gene_name": "Dmel\\CG8526", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPAAKCGCLKKEARVHVIYVGGTIGMIRNESGVLHTAPKVLARQLQEFPSCHDRNYTSKDNDGPMMVLPAVSGAPYRVLYDLIEFCPLMDSSCMGFCDWKRIANEVGKTYKSYDGFVILHGTDTLAYSASALAFMLESLNKPVVFTGAQIPIFEARSDGRENFLGALLIAGNYSIPEVLVFFGNKILRGCRSTKLNSDSFHALDSPNFAPLGRASVNIEINSRQIFRPCNIKPFSLHSELEKNVALLRIYPGISASVVQAILKEPTKGVVLQTFGAGNFPVNREDLLDELREAVHRGVIIVNITQCSAGMVANIYETSQGLMEVGVIPGYDMTQEAAFTKLAYVLSKPEWDIPNKKKVMLLSLRGELTTNKVAKINDIDLIEGVARTLHMSTAMERQQMCSTFYPALVAAAVTEGDVHKLGDLKQYGANLCDTNCDGRSAMHLACFLGKLNCVCFLISAGCPVNVHDRFNRTPLHEAIDTDNHDIINALLKNGAKLNDQPLVQAELLRALTERGKIKRLESFRLAGANLTLADRTGRTALHYACQLGNHEVVDYLLPHYENPYIKDELGMSPIDYAKAANHAHILTLMRFKEKELAKKDPCSCTQ", "length": 605 }, "evidence": [ { "id": "RGD:708388", "url": "https://alliancegenome.org/gene/RGD:708388#orthology", "database": "AGR" }, { "id": "MGI:2144822", "url": "https://alliancegenome.org/gene/MGI:2144822#orthology", "database": "AGR" }, { "id": "HGNC:20123", "url": "https://alliancegenome.org/gene/HGNC:20123#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070820-14", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070820-14#orthology", "database": "AGR" }, { "id": "SGD:S000004150", "url": "https://alliancegenome.org/gene/SGD:S000004150#orthology", "database": "AGR" }, { "id": "SGD:S000004145", "url": "https://alliancegenome.org/gene/SGD:S000004145#orthology", "database": "AGR" }, { "id": "SGD:S000004147", "url": "https://alliancegenome.org/gene/SGD:S000004147#orthology", "database": "AGR" }, { "id": "SGD:S000004148", "url": "https://alliancegenome.org/gene/SGD:S000004148#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "asparagine metabolic process", "id": "GO:0006528", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006528", "evidence": [ { "database": "UniProtKB", "id": "Q9W4N6", "url": "https://www.uniprot.org/uniprotkb/Q9W4N6" } ], "pmid": "" }, { "name": "amino acid metabolic process", "id": "GO:0006520", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006520", "evidence": [ { "database": "UniProtKB", "id": "Q9W4N6", "url": "https://www.uniprot.org/uniprotkb/Q9W4N6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "asparaginase activity", "id": "GO:0004067", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004067", "evidence": [ { "database": "UniProtKB", "id": "Q9W4N6", "url": "https://www.uniprot.org/uniprotkb/Q9W4N6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 134, "end_pos": 136, "annotation": "n_glycosylation_sequon" }, { "start_pos": 203, "end_pos": 205, "annotation": "n_glycosylation_sequon" }, { "start_pos": 231, "end_pos": 233, "annotation": "n_glycosylation_sequon" }, { "start_pos": 343, "end_pos": 345, "annotation": "n_glycosylation_sequon" }, { "start_pos": 349, "end_pos": 351, "annotation": "n_glycosylation_sequon" }, { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-DME-6797627", "name": "ASPG hydrolyses L-Asn to L-Asp", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-29642" ], "output_participant_list": [], "enzyme_list": [ "Q9W4N6-1" ], "evidence": [ { "id": "R-DME-6797627", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6797627" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-29642", "participant_name": "L-Asn [cytosol]", "crossref": [ { "id": "58048", "database": "ChEBI", "url": "" }, { "id": "ZINC000001532556", "database": "ZINC", "url": "" }, { "id": "C00152", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "Q9W4N6", "gene_name": "CG-6428", "activity": [ { "ec_number": "3.5.1.1", "activity": "L-asparagine + H2O = L-aspartate + NH4(+).", "evidence": [ { "id": "Q9W4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W4N6" } ] }, { "ec_number": "3.5.1.1", "activity": "", "evidence": [ { "id": "Q9W4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W4N6" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9W4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W4N6" }, { "id": "PF17763", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17763" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Asparaginase/glutaminase C-terminal", "eco_id": "ECO_0000259", "start_pos": 284, "end_pos": 397, "start_aa": "Asn", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q9W4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W4N6" }, { "id": "PF00710", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00710" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "L-asparaginase N-terminal", "eco_id": "ECO_0000259", "start_pos": 51, "end_pos": 264, "start_aa": "Arg", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.5.1.1", "ec_name": "L-asparagine + H2O = L-aspartate + NH4(+).", "evidence": [ { "id": "3.5.1.1", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.1.1" }, { "id": "3.5.1.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.5.1.1" } ] } ], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 134, "end_pos": 136 }, { "start_pos": 203, "end_pos": 205 }, { "start_pos": 231, "end_pos": 233 }, { "start_pos": 343, "end_pos": 345 }, { "start_pos": 349, "end_pos": 351 }, { "start_pos": 36, "end_pos": 38 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9W4P4-1", "uniprot_ac": "Q9W4P4", "uniprot_id": "Q9W4P4_DROME", "mass": { "chemical_mass": 51153.0, "monoisotopic_mass": 51153.0 }, "refseq": { "ac": "NP_570081", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_570081" }, "gene_names": [ { "name": "Dmel\\CG15239", "type": "recommended", "evidence": [ { "id": "Q9W4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W4P4" } ] }, { "name": "CG15239", "type": "synonym", "evidence": [ { "id": "NP_570081", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_570081" }, { "id": "Q9W4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W4P4" } ] }, { "name": "Dmel\\CG15239", "type": "synonym", "evidence": [ { "id": "NP_570081", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_570081" } ] }, { "name": "Dmel_CG15239", "type": "synonym", "evidence": [ { "id": "Q9W4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W4P4" } ] } ], "protein_names": [ { "name": "DUF4773 domain-containing protein", "type": "recommended", "evidence": [ { "id": "Q9W4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W4P4/entry#names_and_taxonomy" } ] }, { "name": "CG15239-PA", "type": "synonym", "evidence": [ { "id": "NP_570081", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_570081" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_570081", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_570081" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W4P4", "url": "https://www.uniprot.org/uniprotkb/Q9W4P4" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG15239", "url": "https://www.uniprot.org/uniprotkb/Q9W4P4", "locus": { "chromosome": "X", "start_pos": 3890486, "end_pos": 3884168, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0029681", "url": "https://www.ensemblgenomes.org/id/FBgn0029681" } ] } } ], "crossref": [ { "id": "FB:FBgn0029681", "url": "https://alliancegenome.org/gene/FB:FBgn0029681", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0029681", "url": "https://bgee.org/?page=gene&gene_id=FBgn0029681", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0029681", "url": "https://flybase.org/reports/FBgn0029681", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "31343", "url": "https://www.ncbi.nlm.nih.gov/gene/31343", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR031941", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031941", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG15239", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG15239", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GPGCAKI", "url": "https://omabrowser.org/oma/group/GPGCAKI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W4P4", "url": "https://www.orthodb.org/?gene=Q9W4P4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR36299", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR36299", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR36299:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR36299:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15998", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15998", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_570081", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_570081", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W4P4", "url": "https://www.uniprot.org/uniprotkb/Q9W4P4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W4P4-1", "url": "https://www.uniprot.org/uniprotkb/Q9W4P4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTSSRNMLLMLLLVASASILQLEAKTVFRRTDKISENFKQLDLPPEEIDPNVAPPESEPPKVEDVADVADEVVNAVSPASSIDESANEIASGDVDTPNAAASVAEAVAPAAAVPEVAEAAAPAVATTLAAKPTTAPTTAKPENPISKFCKCSESHCDCCRKFGLPLLPSGPGCAKIAYVGNDEMSVSLKYGGITLASRRISSKRARPICVGLPGGYSKFCGKVYGLSRSKESKDFKACLAFELRSDDEVEASLRVSCFKFGPEGVRVAEAEPLPVKPSSDDDDDDDDDLFGFAAGGDDDEDEEDDYDSDNDTDADADDDDDTEDYADDDEAEAPEDADYGGFSLAGLLDELDDDDDEKPVKKPAAAAASAAADQTREHVIADGQVTATTTNGDQVQSKDDTGAPAAGEAVAAAAPAAPAAPLAAPAAAAPIEGEVAAAVTPATTAAADEDSTTPKSKKSKKAKKNKKKKAAAEATDETGFAYELLNGILDFFN", "length": 493, "header": "tr|Q9W4P4-1|Q9W4P4_DROME Isoform 1 of DUF4773 domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG15239 PE=4 SV=1 CANONICAL=Q9W4P4-1" }, "isoforms": [ { "isoform_ac": "Q9W4P4-1", "url": "https://www.uniprot.org/uniprotkb/Q9W4P4/entry#Q9W4P4-1", "sequence": { "sequence": "MTSSRNMLLMLLLVASASILQLEAKTVFRRTDKISENFKQLDLPPEEIDPNVAPPESEPPKVEDVADVADEVVNAVSPASSIDESANEIASGDVDTPNAAASVAEAVAPAAAVPEVAEAAAPAVATTLAAKPTTAPTTAKPENPISKFCKCSESHCDCCRKFGLPLLPSGPGCAKIAYVGNDEMSVSLKYGGITLASRRISSKRARPICVGLPGGYSKFCGKVYGLSRSKESKDFKACLAFELRSDDEVEASLRVSCFKFGPEGVRVAEAEPLPVKPSSDDDDDDDDDLFGFAAGGDDDEDEEDDYDSDNDTDADADDDDDTEDYADDDEAEAPEDADYGGFSLAGLLDELDDDDDEKPVKKPAAAAASAAADQTREHVIADGQVTATTTNGDQVQSKDDTGAPAAGEAVAAAAPAAPAAPLAAPAAAAPIEGEVAAAVTPATTAAADEDSTTPKSKKSKKAKKNKKKKAAAEATDETGFAYELLNGILDFFN", "length": 493, "header": "tr|Q9W4P4-1|Q9W4P4_DROME Isoform 1 of DUF4773 domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG15239 PE=4 SV=1 CANONICAL=Q9W4P4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 440, "start_aa": "Thr", "end_pos": 440, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr440", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W4P4", "url": "https://www.uniprot.org/uniprotkb/Q9W4P4" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W4P4", "url": "https://www.uniprot.org/uniprotkb/Q9W4P4" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W4P4", "url": "https://www.uniprot.org/uniprotkb/Q9W4P4" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W4P4", "url": "https://www.uniprot.org/uniprotkb/Q9W4P4" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W4P4", "url": "https://www.uniprot.org/uniprotkb/Q9W4P4" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W4P4", "url": "https://www.uniprot.org/uniprotkb/Q9W4P4" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W4P4", "url": "https://www.uniprot.org/uniprotkb/Q9W4P4" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W4P4", "url": "https://www.uniprot.org/uniprotkb/Q9W4P4" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W4P4", "url": "https://www.uniprot.org/uniprotkb/Q9W4P4" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W4U6", "url": "https://www.uniprot.org/uniprotkb/Q9W4U6" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W4U6", "url": "https://www.uniprot.org/uniprotkb/Q9W4U6" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, 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Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W4U6", "url": "https://www.uniprot.org/uniprotkb/Q9W4U6" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W4U6", "url": "https://www.uniprot.org/uniprotkb/Q9W4U6" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi 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"MEYKMIAPEHSEQVMEHLRRNFFADEPLNKAAGLCQNGSSCPALEAHCAEAIQHRMSVMAVDAKEKDTLKIVGVVLNGILKPGDTAKALSKLDCNDDADFRKIFDLLHRHNLKHNLFEHFDVDCMFDVRILSVDSCYRGQGIANELVKRSVAVAKKNGFRLLKADATGIFSQKIFRSHGFEVFSEQPYSKYTDENGKVILPVEAPHIKLQQLYKAICADDQDEKKQSL", "length": 228, "header": "tr|Q9W4Y1-1|Q9W4Y1_DROME Isoform 1 of aralkylamine N-acetyltransferase OS=Drosophila melanogaster OX=7227 GN=AANATL7 PE=3 SV=2 CANONICAL=Q9W4Y1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W4Y1", "url": "https://www.uniprot.org/uniprotkb/Q9W4Y1" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W4Y1", "url": "https://www.uniprot.org/uniprotkb/Q9W4Y1" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W4Y1", "url": "https://www.uniprot.org/uniprotkb/Q9W4Y1" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W4Y1", "url": "https://www.uniprot.org/uniprotkb/Q9W4Y1" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W4Y1", "url": "https://www.uniprot.org/uniprotkb/Q9W4Y1" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W4Y1", "url": "https://www.uniprot.org/uniprotkb/Q9W4Y1" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W4Y1", "url": "https://www.uniprot.org/uniprotkb/Q9W4Y1" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W4Y1", "url": "https://www.uniprot.org/uniprotkb/Q9W4Y1" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W4Y1", "url": "https://www.uniprot.org/uniprotkb/Q9W4Y1" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W4Y1", "url": "https://www.uniprot.org/uniprotkb/Q9W4Y1" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W4Y1", "url": "https://www.uniprot.org/uniprotkb/Q9W4Y1" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG13759", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG13759", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "aralkylamine N-acetyltransferase activity", "id": "GO:0004059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004059", "evidence": [ { "database": "UniProtKB", "id": "Q9W4Y1", "url": "https://www.uniprot.org/uniprotkb/Q9W4Y1" } ], "pmid": "" }, { "name": "N-acetyltransferase activity", "id": "GO:0008080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008080", "evidence": [ { "database": "UniProtKB", "id": "Q9W4Y1", "url": "https://www.uniprot.org/uniprotkb/Q9W4Y1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 37, "end_pos": 39, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "25217", "name": "", "equation": "serotonin + acetyl-CoA = N-acetylserotonin + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q94521-1", "Q9VMG0-1", "A1ZBI8-1", "A1ZBI6-1", "A1ZBI9-1", "Q9W4Y1-1", "Q9VIQ1-1", "Q9W469-1", "A0ACD4DAR7-1" ], "evidence": [ { "id": "25217", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/25217" } ] }, { "id": "51376", "name": "", "equation": "dopamine + hexadecanoyl-CoA = N-hexadecanoyl-dopamine + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q94521-1", "Q9VMG0-1", "A1ZBI8-1", "A1ZBI6-1", "A1ZBI9-1", "Q9W4Y1-1", "Q9VIQ1-1", "Q9W469-1", "A0ACD4DAR7-1" ], "evidence": [ { "id": "51376", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/51376" } ] }, { "id": "51380", "name": "", "equation": "dopamine + (9Z)-octadecenoyl-CoA = N-(9Z-octadecanoyl)-dopamine + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q94521-1", "Q9VMG0-1", "A1ZBI8-1", "A1ZBI6-1", "A1ZBI9-1", "Q9W4Y1-1", "Q9VIQ1-1", "Q9W469-1", "A0ACD4DAR7-1" ], "evidence": [ { "id": "51380", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/51380" } ] }, { "id": "51384", "name": "", "equation": "serotonin + hexadecanoyl-CoA = N-hexadecanoyl-serotonin + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q94521-1", "Q9VMG0-1", "A1ZBI8-1", "A1ZBI6-1", "A1ZBI9-1", "Q9W4Y1-1", "Q9VIQ1-1", "Q9W469-1", "A0ACD4DAR7-1" ], "evidence": [ { "id": "51384", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/51384" } ] }, { "id": "51388", "name": "", "equation": "dopamine + acetyl-CoA = N-acetyldopamine + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q94521-1", "Q9VMG0-1", "A1ZBI8-1", "A1ZBI6-1", "A1ZBI9-1", "Q9W4Y1-1", "Q9VIQ1-1", "Q9W469-1", "A0ACD4DAR7-1" ], "evidence": [ { "id": "51388", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/51388" } ] }, { "id": "51392", "name": "", "equation": "serotonin + (9Z)-octadecenoyl-CoA = N-(9Z-octadecenoyl)-serotonin + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q94521-1", "Q9VMG0-1", "A1ZBI8-1", "A1ZBI6-1", "A1ZBI9-1", "Q9W4Y1-1", "Q9VIQ1-1", "Q9W469-1", "A0ACD4DAR7-1" ], "evidence": [ { "id": "51392", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/51392" } ] }, { "id": "51396", "name": "", "equation": "serotonin + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = N-[(5Z,8Z,11Z,14Z)-eicosatetraenoyl]-serotonin + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q94521-1", "Q9VMG0-1", "A1ZBI8-1", "A1ZBI6-1", "A1ZBI9-1", "Q9W4Y1-1", "Q9VIQ1-1", 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"https://www.uniprot.org/uniprotkb/Q9W4Y8", "locus": { "chromosome": "X", "start_pos": 2409365, "end_pos": 2410901, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0040385", "url": "https://www.ensemblgenomes.org/id/FBgn0040385" } ] } } ], "crossref": [ { "id": "FB:FBgn0040385", "url": "https://alliancegenome.org/gene/FB:FBgn0040385", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0040385", "url": "https://bgee.org/?page=gene&gene_id=FBgn0040385", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0040385", "url": "https://flybase.org/reports/FBgn0040385", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "31226", "url": "https://www.ncbi.nlm.nih.gov/gene/31226", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR032057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG12496", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG12496", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "STQMGDQ", "url": "https://omabrowser.org/oma/group/STQMGDQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W4Y8", "url": "https://www.orthodb.org/?gene=Q9W4Y8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF16056", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16056", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_570003", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_570003", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W4Y8", "url": "https://www.uniprot.org/uniprotkb/Q9W4Y8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W4Y8-1", "url": "https://www.uniprot.org/uniprotkb/Q9W4Y8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLKWTASAQRLNEIPVHDQDANQPQRRRLQRRQRRQRRATIANKENVPDTVGYTSTPVPITRLRNSPLVLAPLSDIRNVTPEAVVRSQAPQRVQSVRYATTLPRFAEDYSPNGLPSGQHLALRGLAPLDPFLGQPRYIVGSGAGVNKLKQRRLDEDFVATLEPELQETAVPEPPTPKVEVRPSTPQPASTQMGDQTLDRLIDAILDSACKANASSKKKPRRSTFNLRRRTLVKQQMESNCPQEVLSPSYAPGDDPASDLSFGLVPLPMHNLMPTPEPASPLAKIPHNLLVQLATPVAPKSAPCDNTFCLETPVKALKRTRKEIVAKESPIKRYKVDERNYFEVGLALPSSIYV", "length": 353, "header": "tr|Q9W4Y8-1|Q9W4Y8_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=EG:BACH7M4.4 PE=4 SV=1 CANONICAL=Q9W4Y8-1" }, "isoforms": [ { "isoform_ac": "Q9W4Y8-1", "url": "https://www.uniprot.org/uniprotkb/Q9W4Y8/entry#Q9W4Y8-1", "sequence": { "sequence": "MLKWTASAQRLNEIPVHDQDANQPQRRRLQRRQRRQRRATIANKENVPDTVGYTSTPVPITRLRNSPLVLAPLSDIRNVTPEAVVRSQAPQRVQSVRYATTLPRFAEDYSPNGLPSGQHLALRGLAPLDPFLGQPRYIVGSGAGVNKLKQRRLDEDFVATLEPELQETAVPEPPTPKVEVRPSTPQPASTQMGDQTLDRLIDAILDSACKANASSKKKPRRSTFNLRRRTLVKQQMESNCPQEVLSPSYAPGDDPASDLSFGLVPLPMHNLMPTPEPASPLAKIPHNLLVQLATPVAPKSAPCDNTFCLETPVKALKRTRKEIVAKESPIKRYKVDERNYFEVGLALPSSIYV", "length": 353, "header": "tr|Q9W4Y8-1|Q9W4Y8_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=EG:BACH7M4.4 PE=4 SV=1 CANONICAL=Q9W4Y8-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 175, "start_aa": "Thr", "end_pos": 175, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr175", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 274, "start_aa": "Thr", "end_pos": 274, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr274", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W4Y8", "url": "https://www.uniprot.org/uniprotkb/Q9W4Y8" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W4Y8", "url": "https://www.uniprot.org/uniprotkb/Q9W4Y8" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W4Y8", "url": "https://www.uniprot.org/uniprotkb/Q9W4Y8" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W4Y8", "url": "https://www.uniprot.org/uniprotkb/Q9W4Y8" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W4Y8", "url": "https://www.uniprot.org/uniprotkb/Q9W4Y8" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W4Y8", "url": "https://www.uniprot.org/uniprotkb/Q9W4Y8" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W4Y8", "url": "https://www.uniprot.org/uniprotkb/Q9W4Y8" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W4Y8", "url": "https://www.uniprot.org/uniprotkb/Q9W4Y8" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W4Y8", "url": "https://www.uniprot.org/uniprotkb/Q9W4Y8" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG3071", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3071", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ATYQVVH", "url": "https://omabrowser.org/oma/group/ATYQVVH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W4Z9", "url": "https://www.orthodb.org/?gene=Q9W4Z9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19924", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19924", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19924:SF26", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19924:SF26", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09384", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09384", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6791226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_569993", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_569993", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W4Z9", "url": "https://www.uniprot.org/uniprotkb/Q9W4Z9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W4Z9-1", "url": "https://www.uniprot.org/uniprotkb/Q9W4Z9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQNSFLPLNTRRFRQRAQVETPDTVYWDRLAKPELLKEHNTIDYLDFSPSDPDNFVVTCSVRVQIYNLVTMLVVKNLSRFQKTAYGATFRQDGRLLAAGDEEGHVKLFDTTSRNILRLFKGHTAPVHRTFFTADKLQLASFGDDKSVRLWDVANEKVVQTYEDTHTDYVRAGAMHPQAGHMFVSGGYDGKIKLYDTRAETAVQRTLDHGAPVESMLFLPNGSIFVSAGGSQVRVWDLISGCRLLTMMSQHHKTVTCLRLGSDGRRLLSGGLDRHVKIYDVSTYKTVHTLTYPNAVVSMAVADGDQAVVAGMVDGLVSIRRMMVDSKPSHLKKIRADRARKYFVSTKRTNNTQEVDHTIKDHVKGPGLKSYDVHLRQFNHKKALDDVMNAQKMQYQPELIVAVITDLLHRGSLGKALTGRHEAALVRFIDFICNHLGEVRFMRPLMMAASTVLDVFEQRLVAYSQKLMKALQRLSLAMQEEVRLTAELMRMKGAVDMLIGISMDNSEVAHKPTYVETKTPKMHPSVAAQNYVVLVE", "length": 535, "header": "tr|Q9W4Z9-1|Q9W4Z9_DROME Isoform 1 of U3 small nucleolar RNA-associated protein 15 homolog OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG3071 PE=1 SV=1 CANONICAL=Q9W4Z9-1" }, "isoforms": [ { "isoform_ac": "Q9W4Z9-1", "url": "https://www.uniprot.org/uniprotkb/Q9W4Z9/entry#Q9W4Z9-1", "sequence": { "sequence": "MQNSFLPLNTRRFRQRAQVETPDTVYWDRLAKPELLKEHNTIDYLDFSPSDPDNFVVTCSVRVQIYNLVTMLVVKNLSRFQKTAYGATFRQDGRLLAAGDEEGHVKLFDTTSRNILRLFKGHTAPVHRTFFTADKLQLASFGDDKSVRLWDVANEKVVQTYEDTHTDYVRAGAMHPQAGHMFVSGGYDGKIKLYDTRAETAVQRTLDHGAPVESMLFLPNGSIFVSAGGSQVRVWDLISGCRLLTMMSQHHKTVTCLRLGSDGRRLLSGGLDRHVKIYDVSTYKTVHTLTYPNAVVSMAVADGDQAVVAGMVDGLVSIRRMMVDSKPSHLKKIRADRARKYFVSTKRTNNTQEVDHTIKDHVKGPGLKSYDVHLRQFNHKKALDDVMNAQKMQYQPELIVAVITDLLHRGSLGKALTGRHEAALVRFIDFICNHLGEVRFMRPLMMAASTVLDVFEQRLVAYSQKLMKALQRLSLAMQEEVRLTAELMRMKGAVDMLIGISMDNSEVAHKPTYVETKTPKMHPSVAAQNYVVLVE", "length": 535, "header": "tr|Q9W4Z9-1|Q9W4Z9_DROME Isoform 1 of U3 small nucleolar RNA-associated protein 15 homolog OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG3071 PE=1 SV=1 CANONICAL=Q9W4Z9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W4Z9", "url": "https://www.uniprot.org/uniprotkb/Q9W4Z9" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W4Z9", "url": "https://www.uniprot.org/uniprotkb/Q9W4Z9" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W4Z9", "url": "https://www.uniprot.org/uniprotkb/Q9W4Z9" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W4Z9", "url": "https://www.uniprot.org/uniprotkb/Q9W4Z9" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W4Z9", "url": "https://www.uniprot.org/uniprotkb/Q9W4Z9" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W4Z9", "url": "https://www.uniprot.org/uniprotkb/Q9W4Z9" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W4Z9", "url": "https://www.uniprot.org/uniprotkb/Q9W4Z9" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W4Z9", "url": "https://www.uniprot.org/uniprotkb/Q9W4Z9" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W4Z9", "url": "https://www.uniprot.org/uniprotkb/Q9W4Z9" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W4Z9", "url": "https://www.uniprot.org/uniprotkb/Q9W4Z9" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W4Z9", "url": "https://www.uniprot.org/uniprotkb/Q9W4Z9" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG3071", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3071", "resource": "KEGG Pathway" }, { "id": "R-DME-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" } ], "orthologs": [ { "uniprot_canonical_ac": "A2RRU3-1", "protein_name": "U3 small nucleolar RNA-associated protein 15 homolog", "gene_name": "Utp15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGYKPVVIQTYPVLGEKITQDTLYWNNYKTPVQIKEFGAVSKVDFSPQPPYNYAVTASSRIHIYGRYSQEPVKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFDISGRAPLRQFEGHTKAVHTVDFTADKYHVVSGADDYTVKLWDIPNSKEILTFKEHSDYVRCGCASKLNPDLFVTGSYDHTVKMFDARTNKNVLCVEHGQPVESVLLFPSGGLLVSAGGRYVKVWDMLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKIYSTTSYKVVHSFDYAASILSLALSHQDETVVVGMTNGILSVKHRKSEAKKESLPRRRRPAYRTFIKGKIYTKQRDDIVVTRPAKKHLEWYDRDLKSFRISKALDRVLEPNCVIKTPEVTVSIIKELNRRGVLANALAGRDEKEITRVLNFLIRNLSQPRFAPVLINAAEIIIDIYLPVIGQSSVVDKKFIVLQGLVEKEIDYQRELLETLGMMDMLFATMTRNGSAPVWEHVPAELPEEKTESPRQPSDTDKNS", "length": 528 }, "evidence": [ { "id": "MGI:2145443", "url": "https://alliancegenome.org/gene/MGI:2145443#orthology", "database": "AGR" }, { "id": "HGNC:25758", "url": "https://alliancegenome.org/gene/HGNC:25758#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-3831", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-3831#orthology", "database": "AGR" }, { "id": "RGD:1310992", "url": "https://alliancegenome.org/gene/RGD:1310992#orthology", "database": "AGR" }, { "id": "FB:FBgn0023527", "url": "https://alliancegenome.org/gene/FB:FBgn0023527#orthology", "database": "AGR" }, { "id": "SGD:S000004699", "url": "https://alliancegenome.org/gene/SGD:S000004699#orthology", "database": "AGR" }, { "id": "Q9W4Z9", "url": "https://omabrowser.org/oma/group/Q9W4Z9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A7MB12-1", "protein_name": "U3 small nucleolar RNA-associated protein 15 homolog", "gene_name": "UTP15", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAGYKPVSIQTYPVLGEKITQDTLYWNNYKTPVQIKEFGAVSKVDFSPQPPYNYAVTASSRIHIYGRYSQEPIKTFSRFKDTAYCATFRQDGRLLVAGSEDGGVQLFDISGRAPLRQFEGHTKAVHSVDFTADKYHVVSGADDYTVKLWDIPNSKEILTFKEHSDYVRCGCASKLNTDLFVTGSYDHTVKMFDARTNQSVISVEHGQPVESVLLFPSGGLLVSAGGRYVKVWDMLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKVYSTTSYKVVHSFDYTASILSLALAHEDETIVVGMTNGILSVKHRKSEAKKDSVPRRRRPAYRTFIKGKNYMKQQDDILINRPSKKHLELYDRDLKNFRISKALDRVLEPTCTIKTPEVTVSIIKELNRRGVLANALAGRDEKEISRVLNFLIRNLSQPRFAPVLINAAEIIIDIYLPVIGQSPVVDKKFLILQGLVEKEIDYQRELLETLGMMDMLFATMTRKESTSVLQHNTSDGFLENNKIES", "length": 519 }, "evidence": [ { "id": "Q9W4Z9", "url": "https://omabrowser.org/oma/group/Q9W4Z9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1S2K2-1", "protein_name": "U3 small nucleolar RNA-associated protein 15 homolog", "gene_name": "UTP15", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGYKPVAIQIYPILGEKITQDTLYWNNYKTPVQIKEFGAVSKVDFSPQPPYNYAVTASSRIHIYGRYSQEPIKTFSRFKDTAYCATFRQDGRLLIAGSEDGGVQLFDISGRAPLRQFEGHTKAVHTVDFTADKYHVVSGADDYTVKLWDIPNSKEILTFKEHSDYVRCGCASKLNPDLFVTGSYDHTVKMFDARTNQSVISVEHGQPVESVLLFPSGGLLVSAGGRYVKVWDVLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKVYSTTSYKVVHSFDYAASILSLALAHEDETIVVGMTNGILSVKHRKSEAKKESVSRRRRPAYRTFIKGKNYMKQQDDILINRPSKKHLELYDRDLKNFRISKALDRVLEPSCTIKTPEITVSIIKELNRRGVLANALAGRDEKEISRVLNFLIRNLSQPRFAPVLINAAEIVIDIYLPVIGQSPVVDKKFLLLQGLVEKEIDYQRELLETLGMMDMLFATMTRKESTSVLQQTPDGFLENKRIES", "length": 518 }, "evidence": [ { "id": "Q9W4Z9", "url": "https://omabrowser.org/oma/group/Q9W4Z9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O82266-1", "protein_name": "Protein SLOW WALKER 1", "gene_name": "SWA1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEEELRVRLNDHQVSKVFPVKPKSTAKPVSESETPESRYWSSFKNHSTPNLVSSVAALAFSPVHPHSLAVAHSATVSLFSSQSLSSSRRFSFRDVVSSVCFRSDGALFAACDLSGVVQVFDIKERMALRTLRSHSAPARFVKYPVQDKLHLVSGGDDGVVKYWDVAGATVISDLLGHKDYVRCGDCSPVNDSMLVTGSYDHTVKVWDARVHTSNWIAEINHGLPVEDVVYLPSGGLIATAGGNSVKVWDLIGGGKMVCSMESHNKTVTSLRVARMESAESRLVSVALDGYMKVFDYGRAKVTYSMRFPAPLMSLGLSPDGSTRVIGGSNGMVFAGKKKVRDVVGGQKKSLNLWSLISDVDESRRRALRPTYFRYFQRGQSEKPSKDDYLVKEKKGLKLTRHDKLLKKFRHKEALVSVLEEKKPANVVAVMEELVARRKLMKCVSNMEEGELGMLLGFLQRYCTVQRYSGLLMGLTKKVLETRAEDIKGKNEFKGLLRNLKREVNQEIRIQQSLLEIQGVIAPLMRIAGRS", "length": 530 }, "evidence": [ { "id": "Q9W4Z9", "url": "https://omabrowser.org/oma/group/Q9W4Z9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q04305-1", "protein_name": "U3 small nucleolar RNA-associated protein 15", "gene_name": "UTP15", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSTARPRIITSKAPLLPQQTTPEQRYWRQYTSAQLVKEHNSVTHISFNPQHPHDFAVTSSTRVQIFSSRTRQVIKTFSRFKDVVYSASFRSDGKLLCAGDATGLVSVYDSYNPRTILLSINASTHPTHVTKFHTQDNKILATASDDRVTRLWDISNAYEPQLELTGATDYVRTLSFIPAAPHLVATGSYDGLIRLYDTRSSGSTPIYSLNHDQPVENVIAVSPTQIVSCGGNNFKVWDLTSNKKLYERGNFNKAVTCLDYVENFDSPMQSALIASSLDGHVKVFDPLDNFQVKFGWKFSGPVLSCAVSPSTAQGNRHLVAGLSSGLLAIRTKKKEKRSSDKENAPASFNKNAKSNNFQRMMRGSEYQGDQEHIIHNDKVRSQRRMRAFERNINQFKWSEALDNAFVPGMAKELTLTVLQELRKRGKVRVALYGRDESTLEPLLNWCLKGIEDVRSASIVADWVAVVLELYGNTLESSPVLQELMIDLKTKVRHEIHKSKEAQRIEGMLQLLTS", "length": 513 }, "evidence": [ { "id": "MGI:2145443", "url": "https://alliancegenome.org/gene/MGI:2145443#orthology", "database": "AGR" }, { "id": "HGNC:25758", "url": "https://alliancegenome.org/gene/HGNC:25758#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-3831", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-3831#orthology", "database": "AGR" }, { "id": "RGD:1310992", "url": "https://alliancegenome.org/gene/RGD:1310992#orthology", "database": "AGR" }, { "id": "FB:FBgn0023527", "url": "https://alliancegenome.org/gene/FB:FBgn0023527#orthology", "database": "AGR" }, { "id": "SGD:S000004699", "url": "https://alliancegenome.org/gene/SGD:S000004699#orthology", "database": "AGR" }, { "id": "Q9W4Z9", "url": "https://omabrowser.org/oma/group/Q9W4Z9/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54QV4-1", "protein_name": "WD40 repeat-containing protein", "gene_name": "utp15", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MMNDYTFLHNLPDVPIPYINPVVTGDSWKLKELQNKKYSSMITRVESNPINSKEVCVTFGNCVRIITSNSKKVEEREITSFRDTPYGASYRDDGKLIVVGGEDPIIKLIDVSSKNTLRKFQGHTGGIQCTRFIEKGSLISGSNDNTVRTWAIETGEQLQMVGKHKDKVHCMTRHPTNGDNIWMTGGYDHCVKLWDIRGNKTQSSTITLDHGAPVEDLIMLGASGTMAISVGGNYFKVWDLLNGSTGKQVYQGTHSMKSLTSIHLSNSKDRFITSGLDHTVRVFSTQSYSLINSYEFSEPLLSLTLINDRKIIAGSAKGTLFYARKTNPITISKAKLSNSDLKNNNIDPVIQLKLKKSQQHNQTLVIDDTLGIYKSSHLDRLLRKFEHKTAFDTAVLLNKNIDFIFKVVCELSRRDALDIVLKNREVSELDSILQMVNKLVNTIKYQQCGILLLEKIVEFYHPSIFQENKSIISTMNSIKINLIKEQKKQSQLLELSGALDLLYSNSTNSNIPKTIQKRKFEEDEQEQEN", "length": 529 }, "evidence": [ { "id": "Q9W4Z9", "url": "https://omabrowser.org/oma/group/Q9W4Z9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5F3D7-1", "protein_name": "U3 small nucleolar RNA-associated protein 15 homolog", "gene_name": "UTP15", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MASYKPVVIPAVPKLGEKITQDTLYWRGYKTPVQIKEFGAINKIDFSPVPPYNYAVTASSRVHIYGRYSQEPIKTFSRFKDAAYCATYRDDGKLLVAGSEEGSIRLFDISGRAPLRQFDGHTKAVHVVGFLSDKYRIFSGGDDYSSSLWDIPSATEIVSYSEHSDYVRCGCASKLNGDVFITGSYDHTVKVFDARTKSSVMTIEHGHPVESVLLFPSGGLLVSAGGRYVKVWDVLKGGQLLVSLKNHHKTVTCLCLNSSGQRLLSGSLDRHVKIYSTTSYKVVHSFNYATSILSLALSPEDETIIVGMTNGVLNVKHRKPEESKEKSQKKRQPAYRTYVKGRNYMPKQEDFFVSKPGRCIMRKYDKLLKSFQSSKALDAVLEPHIRLYTPEVTVAVMQELNRRGTLRSALAGRDEKQISLLLTFVTRRVIEPRFTPVLITVADMITDIYQPVVGQSALVDKQFLRLQEAIGREIDYQEELLEVLGMMDALFATLTEKRATYLEENKSNGLTKTLDQDISI", "length": 520 }, "evidence": [ { "id": "Q9W4Z9", "url": "https://omabrowser.org/oma/group/Q9W4Z9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q7ZW33-1", "protein_name": "U3 small nucleolar RNA-associated protein 15 homolog", "gene_name": "utp15", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASFKPTKVLSYPKLGEKVTEETLYWKNYKPPVQIKEFGAVSKIDFSPLPPHNYAVTASTRVHIYGLHSQEPIRNFTRFHDTAYGGSFRGDGKLLVAGSEEGLIRLFDIGGRVSLRQFKGHSKAVHATSFLSDGFRVLSGSDDLTCRVWDVASAVELSSITEHTDYIRAIAPSKLNPDVFVTGSYDHTVKMFDVRSGNSVMTMQHGQPVECVLLYPSEALLVSTGGRYVKVWDLLKGGQQLVSLKNHHKTVTCACLSSSNKLLTASLDRHVKVYNSSYKVVHNFDCASSILSLAVAPDDEAVAVGMTNGVLSIRHRKHKEEKEALTGRRKRGPSYRFFVKGKNFVPRQDDFLVSKPVRQHLQKYDKQLKRFEVSKALDTALETWTRTTKPEVTVAVIMELNRRGTLKNALAGRDEVSLTKILNFLLKHITDPRFSRPLLTVGDIVLDLYQQVIPQSPVVERLLQRLYEILGREAELQQELLQVLGILDTLFASLMPRKEVASFGAAAAAQESQLQAA", "length": 517 }, "evidence": [ { "id": "MGI:2145443", "url": "https://alliancegenome.org/gene/MGI:2145443#orthology", "database": "AGR" }, { "id": "HGNC:25758", "url": "https://alliancegenome.org/gene/HGNC:25758#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-3831", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-3831#orthology", "database": "AGR" }, { "id": "RGD:1310992", "url": "https://alliancegenome.org/gene/RGD:1310992#orthology", "database": "AGR" }, { "id": "FB:FBgn0023527", "url": "https://alliancegenome.org/gene/FB:FBgn0023527#orthology", "database": "AGR" }, { "id": "SGD:S000004699", "url": "https://alliancegenome.org/gene/SGD:S000004699#orthology", "database": "AGR" }, { "id": "Q9W4Z9", "url": "https://omabrowser.org/oma/group/Q9W4Z9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8C7V3-1", "protein_name": "U3 small nucleolar RNA-associated protein 15 homolog", "gene_name": "Utp15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGYKPVAIQTYPVLGEKITQDTLYWNNYKTPVQIKEFGAVSKVDFSPQLPYNYAVTASSRIHIYGRYSQEPVKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFDINGRAPLRQFEGHTKAVHTVDFTADNYHVVSGADDYTVKLWDIPNSKEILTFKEHSDYVRCGCASKLNPDLFVTGSYDHTVKIFDARTNKNVLCVEHGQPVESVLLFPSGGLLVSAGGRYVKVWDMLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKVYSTTSYKVVHSFDYAASILSLALSHQDETIVVGMTNGILSVKHRKSEAKKTSLPRRRRPAYRTFIKGKNYLKQRDDIMVSRPAKKHLEGYDKDLKSFRVSQALDRVLEPKCVIRTPEVTVSIIKELTRRGVLANALAGRDEKEVTRVLNFLIRNLSQPRFAPVLINAAEIIIDIYLPVIGQSSVVDKKFIVLQELVEKEIDYQRELLETLGMMDMLFATMTRNDSDPVPEHVPAELPEEKTESPTQPSDTDKNS", "length": 528 }, "evidence": [ { "id": "MGI:2145443", "url": "https://alliancegenome.org/gene/MGI:2145443#orthology", "database": "AGR" }, { "id": "HGNC:25758", "url": "https://alliancegenome.org/gene/HGNC:25758#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-3831", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-3831#orthology", "database": "AGR" }, { "id": "RGD:1310992", "url": "https://alliancegenome.org/gene/RGD:1310992#orthology", "database": "AGR" }, { "id": "FB:FBgn0023527", "url": "https://alliancegenome.org/gene/FB:FBgn0023527#orthology", "database": "AGR" }, { "id": "SGD:S000004699", "url": "https://alliancegenome.org/gene/SGD:S000004699#orthology", "database": "AGR" }, { "id": "Q9W4Z9", "url": "https://omabrowser.org/oma/group/Q9W4Z9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TED0-1", "protein_name": "U3 small nucleolar RNA-associated protein 15 homolog", "gene_name": "UTP15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGYKPVAIQTYPILGEKITQDTLYWNNYKTPVQIKEFGAVSKVDFSPQPPYNYAVTASSRIHIYGRYSQEPIKTFSRFKDTAYCATFRQDGRLLVAGSEDGGVQLFDISGRAPLRQFEGHTKAVHTVDFTADKYHVVSGADDYTVKLWDIPNSKEILTFKEHSDYVRCGCASKLNPDLFITGSYDHTVKMFDARTSESVLSVEHGQPVESVLLFPSGGLLVSAGGRYVKVWDMLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKVYSTTSYKVVHSFDYAASILSLALAHEDETIVVGMTNGILSVKHRKSEAKKESLPRRRRPAYRTFIKGKNYMKQRDDILINRPAKKHLELYDRDLKHFRISKALDRVLDPTCTIKTPEITVSIIKELNRRGVLANALAGRDEKEISHVLNFLIRNLSQPRFAPVLINAAEIIIDIYLPVIGQSPVVDKKFLLLQGLVEKEIDYQRELLETLGMMDMLFATMRRKEGTSVLEHTSDGFPENKKIES", "length": 518 }, "evidence": [ { "id": "MGI:2145443", "url": "https://alliancegenome.org/gene/MGI:2145443#orthology", "database": "AGR" }, { "id": "HGNC:25758", "url": "https://alliancegenome.org/gene/HGNC:25758#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-3831", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-3831#orthology", "database": "AGR" }, { "id": "RGD:1310992", "url": "https://alliancegenome.org/gene/RGD:1310992#orthology", 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"categories": [ "Protein" ] } ], "sequence": { "sequence": "MHHPLSGEMEEFFEDSEIFVTGGSGVVGKALVEKLLRSCNVRRIYVLLRPRKQLTAEQRLVRLRQATVFHVLAVQKPEELDKIVAVPGDVSLPGLGIDPSMMQRMKGVSLVYHCAATVRFDEPLREAVRLNVGGTLEALKFAETLPQLRAFIHVSTFYSNPYLTRVEPKYYSSPMDWRLCLRMIDDVADDGMLNALTRKLIMGFPNTYTFTKNLAESLVNDYRHRLPVIVYRPSIVLFAVEDPSPGFSPSLMGAMGLFALVGAGILKTVYLGKDIRLDITPQDIGIKSMLCYTKMGYDIYRQGPPADLPVFLSSSCTHVPHTFTQIAEQMDTLDLWRDVAFEKNLMIPGCHYTDKRWAYQFLVFTKQILPALILDLLLRIFGQKPVLMSAVRKAYQTLEVMQPFMFNNWDSPGVSDMETLSKHGEGSAFNFDAFNHPDIHGLVIQSCSNMLHSIRTHLLREDPKTLERSKRILRIKVFLYRLLRLFLLYKLILWLWRSYLAHLF", "length": 504, "header": "tr|Q9W508-1|Q9W508_DROME Isoform 1 of Fatty acyl-CoA reductase OS=Drosophila melanogaster OX=7227 GN=FarO PE=3 SV=3 CANONICAL=Q9W508-1" }, "isoforms": [ { "isoform_ac": "Q9W508-1", "url": "https://www.uniprot.org/uniprotkb/Q9W508/entry#Q9W508-1", "sequence": { "sequence": "MHHPLSGEMEEFFEDSEIFVTGGSGVVGKALVEKLLRSCNVRRIYVLLRPRKQLTAEQRLVRLRQATVFHVLAVQKPEELDKIVAVPGDVSLPGLGIDPSMMQRMKGVSLVYHCAATVRFDEPLREAVRLNVGGTLEALKFAETLPQLRAFIHVSTFYSNPYLTRVEPKYYSSPMDWRLCLRMIDDVADDGMLNALTRKLIMGFPNTYTFTKNLAESLVNDYRHRLPVIVYRPSIVLFAVEDPSPGFSPSLMGAMGLFALVGAGILKTVYLGKDIRLDITPQDIGIKSMLCYTKMGYDIYRQGPPADLPVFLSSSCTHVPHTFTQIAEQMDTLDLWRDVAFEKNLMIPGCHYTDKRWAYQFLVFTKQILPALILDLLLRIFGQKPVLMSAVRKAYQTLEVMQPFMFNNWDSPGVSDMETLSKHGEGSAFNFDAFNHPDIHGLVIQSCSNMLHSIRTHLLREDPKTLERSKRILRIKVFLYRLLRLFLLYKLILWLWRSYLAHLF", "length": 504, "header": "tr|Q9W508-1|Q9W508_DROME Isoform 1 of Fatty acyl-CoA reductase OS=Drosophila melanogaster OX=7227 GN=FarO PE=3 SV=3 CANONICAL=Q9W508-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W508", "url": "https://www.uniprot.org/uniprotkb/Q9W508" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W508", "url": "https://www.uniprot.org/uniprotkb/Q9W508" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W508", "url": "https://www.uniprot.org/uniprotkb/Q9W508" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W508", "url": "https://www.uniprot.org/uniprotkb/Q9W508" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W508", "url": "https://www.uniprot.org/uniprotkb/Q9W508" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W508", "url": "https://www.uniprot.org/uniprotkb/Q9W508" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W508", "url": "https://www.uniprot.org/uniprotkb/Q9W508" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W508", "url": "https://www.uniprot.org/uniprotkb/Q9W508" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W508", "url": "https://www.uniprot.org/uniprotkb/Q9W508" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W508", "url": "https://www.uniprot.org/uniprotkb/Q9W508" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W508", "url": "https://www.uniprot.org/uniprotkb/Q9W508" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG18031", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG18031", "resource": "KEGG Pathway" }, { "id": "R-DME-9640463", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9640463", "resource": "Reactome", "description": "Wax biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M2BLL5-1", "protein_name": "Fatty acyl-CoA reductase", "gene_name": "far1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVTIPEYYVGKNVLITGATGFMGKVLLEKLLRSCPGVKAAYVLVRPKAGQAPDARIADMINCKLFDRLREDQPDFAGKIVAINSDLTQPNLDLSAEDQETLTGCINVVFHCAATIRFNEPLKDAMQLNVLATQKMVSLAHRMKHLEVFIHVSTAYANCDRELIEEVVYPPPVDYRKLIDTLEWMDDKLVSLMTPRLLGERPNTYTYTKALAEQLVQQECGNLNIAIIRPSIVGASWKEPFPGWIDNFNGPSGIFIAAGKGILRTMRASNNAVADLVPVDVVINTTLAAAWYSGSQRHARPRSLLVYNCTTGGINPFHWGEVEYCINMTFKTNPLEQAFRRPNVNLRSNPFTNQYWTTVSHTLPALLYDGFLMLTGQKPRMMKTITRLHKAMMVLEYFTSHSWVWNTDNVTMLMNQMGAEDKKVFNFDVRQLHWAEYMENYCMGTKKYVLNEELSGLPAARKHLNKLRNIRYTFNTVLVVLIWRIFIARSQMARNIWYFVVSLCFKFLSYFRASSTMRY", "length": 518 }, "evidence": [ { "id": "HGNC:26222", "url": "https://alliancegenome.org/gene/HGNC:26222#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A1ZAI5-1", "protein_name": "Putative fatty acyl-CoA reductase CG5065", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSHAVANKTETEAAPNSSLKQSAAPQPANSHDAKLLNGTLARTNGLTHAASVATSSSGSYGSSSAAGSNAGSGGPTSSASLSIAAGVASSTALPLPPSSNGLQMPYERFRADDTSYVPIAQFYAGRSVFITGGTGFMGKVLVEKLLRSCPEIRNIYLLIRPKRGQEVSARLTELLNAPLFESLRQEKPKELSKVIPISGDITSEELGISEKDQNLLCRNVSVVFHSAATVKFDEKLKLSVTINMLGTKRLVELCHRMLSLDALIHVSTAYCNCDRTDVSEVIYAPPYNPDDIISLINWLPEDILDQLTPRLIGKRPNTYTFTKALAEHMLLKEAGNLPVAIVRPSIVTASLNEPFAGWVDNFNGPTGLVSALAKGMFRTMMCEKNYVADMVPVDIVINLMIAAAWRTATRKSNNLLIYNCCTGQRNPIIWSEFVKHAMTSVRKHPLEGCLWYPTGDLRMNRPMNTLNCIAKHFLPAYILDGVARIMGKKPFVVNVQNKIAKAVECLEYFATRQWRFKDDNVHALLHTLSPKDREIFVFDVRHINWDKYVERYVLGFREFLFKQRPESLPASRKRMLRLYYLHQLTKLVAVLLTWRFLMSRSKRLNDLWSSFLENALRMARLIPFL", "length": 625 }, "evidence": [ { "id": "HGNC:26222", "url": "https://alliancegenome.org/gene/HGNC:26222#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q66H50-1", "protein_name": "Fatty acyl-CoA reductase 1", "gene_name": "Far1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSIPEYYEGKNILLTGATGFLGKVLLEKLLRSCPKVNSVYVLVRQKAGQTPQERVEEILSGKLFDRLRDENPDFRQKIIAINSELTQPKLALSEEDKEIIIDSTNVIFHCAATVRFNENLRDAVQLNVIATRQLILLAQQMKNLEVFMHVSTAYAYCNRKHIDEVVYPPPVDPKKLIDSLEWMDDGLVNDITPKLIGDRPNTYIYTKALAEYVVQQEGAKLNVAIVRPSIVGASWKEPFPGWIDNFNGPSGLFIAAGKGILRTMRASNNALADLVPVDVVVNTSLAAAWYSGVNRPRNIMVYNCTTGSTNPFHWGEVGDYLNHSFKTNPLNQVFRHPYVKFYSNNLMLHYWKGVKHTVPALLLDLALRLTGQKPWMMKTITRLHKAMVFLEYFTSNSWVWNTDNVNMLMNQLNPEDKKTFNIDVRQLHWAEYIENYCMGTKKYVLNEEMSGLPAARKHLNKLRNIRYGFNTILVILIWRIFIARSQMARNIWYFVVSLCYKFLSYFRASSTMRY", "length": 515 }, "evidence": [ { "id": "HGNC:26222", "url": "https://alliancegenome.org/gene/HGNC:26222#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8WVX9-1", "protein_name": "Fatty acyl-CoA reductase 1", "gene_name": "FAR1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVSIPEYYEGKNVLLTGATGFLGKVLLEKLLRSCPKVNSVYVLVRQKAGQTPQERVEEVLSGKLFDRLRDENPDFREKIIAINSELTQPKLALSEEDKEVIIDSTNIIFHCAATVRFNENLRDAVQLNVIATRQLILLAQQMKNLEVFMHVSTAYAYCNRKHIDEVVYPPPVDPKKLIDSLEWMDDGLVNDITPKLIGDRPNTYIYTKALAEYVVQQEGAKLNVAIVRPSIVGASWKEPFPGWIDNFNGPSGLFIAAGKGILRTIRASNNALADLVPVDVVVNMSLAAAWYSGVNRPRNIMVYNCTTGSTNPFHWGEVEYHVISTFKRNPLEQAFRRPNVNLTSNHLLYHYWIAVSHKAPAFLYDIYLRMTGRSPRMMKTITRLHKAMVFLEYFTSNSWVWNTENVNMLMNQLNPEDKKTFNIDVRQLHWAEYIENYCLGTKKYVLNEEMSGLPAARKHLNKLRNIRYGFNTILVILIWRIFIARSQMARNIWYFVVSLCYKFLSYFRASSTMRY", "length": 515 }, "evidence": [ { "id": "HGNC:26222", "url": "https://alliancegenome.org/gene/HGNC:26222#orthology", "database": "AGR" }, { "id": "FB:FBgn0023550", "url": "https://alliancegenome.org/gene/FB:FBgn0023550#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q922J9-1", "protein_name": "Fatty acyl-CoA reductase 1", "gene_name": "Far1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVSIPEYYEGKNILLTGATGFLGKVLLEKLLRSCPRVNSVYVLVRQKAGQTPQERVEEILSSKLFDRLRDENPDFREKIIAINSELTQPKLALSEEDKEIIIDSTNVIFHCAATVRFNENLRDAVQLNVIATRQLILLAQQMKNLEVFMHVSTAYAYCNRKHIDEVVYPPPVDPKKLIDSLEWMDDGLVNDITPKLIGDRPNTYIYTKALAEYVVQQEGAKLNVAIVRPSIVGASWKEPFPGWIDNFNGPSGLFIAAGKGILRTMRASNNALADLVPVDVVVNTSLAAAWYSGVNRPRNIMVYNCTTGSTNPFHWGEVEYHVISTFKRNPLEQAFRRPNVNLTSNHLLYHYWIAVSHKAPAFLYDIYLRMTGRSPRMMKTITRLHKAMVFLEYFTSNSWVWNTDNVNMLMNQLNPEDKKTFNIDVRQLHWAEYIENYCMGTKKYVLNEEMSGLPAARKHLNKLRNIRYGFNTILVILIWRIFIARSQMARNIWYFVVSLCYKFLSYFRASSTMRY", "length": 515 }, "evidence": [ { "id": "HGNC:26222", "url": "https://alliancegenome.org/gene/HGNC:26222#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "Q9W508", "url": "https://www.uniprot.org/uniprotkb/Q9W508" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of lipid storage", "id": "GO:0010884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010884", "evidence": [ { "database": "UniProtKB", "id": "Q9W508", "url": "https://www.uniprot.org/uniprotkb/Q9W508" } ], "pmid": "" }, { "name": "negative regulation of cell growth", "id": "GO:0030308", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030308", "evidence": [ { "database": "UniProtKB", "id": "Q9W508", "url": "https://www.uniprot.org/uniprotkb/Q9W508" } ], "pmid": "" }, { "name": "long-chain fatty-acyl-CoA metabolic process", "id": "GO:0035336", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035336", "evidence": [ { "database": "UniProtKB", "id": "Q9W508", "url": "https://www.uniprot.org/uniprotkb/Q9W508" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "alcohol-forming very long-chain fatty acyl-CoA reductase activity", "id": "GO:0080019", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080019", "evidence": [ { "database": "UniProtKB", "id": "Q9W508", "url": "https://www.uniprot.org/uniprotkb/Q9W508" } ], "pmid": "" }, { "name": "alcohol-forming long-chain fatty acyl-CoA reductase activity", "id": "GO:0102965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0102965", "evidence": [ { "database": "UniProtKB", "id": "Q9W508", "url": "https://www.uniprot.org/uniprotkb/Q9W508" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "52716", "name": "", "equation": "a long-chain fatty acyl-CoA + 2 NADPH + 2 H(+) = a long-chain primary fatty alcohol + 2 NADP(+) + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A1ZAI3-1", "A1ZAI5-1", "Q8MS59-1", "Q960W6-1", "A8JNC9-1", "Q9VDS1-1", "Q9VES5-1", "Q9VES6-1", "Q9W508-1", "Q8MMC6-1", "Q9VCF6-1", "Q9VES7-1", "Q9VG86-1", "Q9VG87-1", "Q9VLJ7-1", "Q9W459-1" ], "evidence": [ { "id": "52716", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/52716" } ] }, { "id": "R-DME-390425", "name": "FAR1 reduces PalmCoA to HXOL", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal matrix", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VG87-1", "Q9VLJ7-1", "Q8MS59-1", "Q9VDS1-1", "Q9VES5-1", "Q8MMC6-1", "Q9VCF6-1", "A8JNC9-1", "A1ZAI3-1", "A1ZAI5-1", "Q960W6-1", "Q9VES6-1", "Q9VES7-1", "Q9VG86-1", "Q9W459-1", "Q9W508-1" ], "evidence": [ { "id": "R-DME-390425", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-390425" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A1ZAI3", "gene_name": "", "activity": [ { "ec_number": "1.2.1.84", "activity": "a long-chain fatty acyl-CoA + 2 NADPH + 2 H(+) = a long-chain primary fatty alcohol + 2 NADP(+) + CoA.", "evidence": [ { "id": "A1ZAI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1ZAI3" } ] }, { "ec_number": "1.2.1.84", "activity": "", "evidence": [ { "id": "A1ZAI3", "database": "UniProtKB", "url": 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"IPR050327", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050327", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG3456", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3456", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TAMWHIV", "url": "https://omabrowser.org/oma/group/TAMWHIV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W509", "url": "https://www.orthodb.org/?gene=Q9W509", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11360", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11360", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11360:SF284", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11360:SF284", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-210991", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-210991", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-433692", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-433692", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-9749641", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9749641", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001284810", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001284810", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W509", "url": "https://www.uniprot.org/uniprotkb/Q9W509", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W509-1", "url": "https://www.uniprot.org/uniprotkb/Q9W509-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVHGPPARRKSQQQHEACEMDMERQPTPPDGGWGWVVVFGSFMIHIVTDGMTYSFGIFYNEFLDYFNEGKGYTAWIASIMVGVTFSSGPISSSFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGFGTGLGFGLIYLPAIVSVTQYFEAKRSLATGIAVCGSGFGTFVFAPLTEFLIGNYGWRGAMLIIGGIVLNCIIFGAMFRPLELEAPPQTPPNTPSTPKLAKKSAIIDQNTTAAELEPLKVLPKDQYLQLPQRTDTAVSGGALCRSNSVGHNLKPNLNNNSNGAVNGQGPTLVTPPQAVVKSTSNDDIARKCHSQLQLTPLRDAHRERSASGTMYRPDALYQGSLHNLPDYVSSRNDLSRSMSGSGVIKRYGSLRQSNNVSQSQEEAKCCGCITCSKETRDTFAEMMNFSLLKDMVFVIFSVSNFCTSIGFNVPYLYVVAYAETLKLTKTDASYLISTIGVANTVGRIILGYISDKPWVNRLLVYNVCLTACGVSTAMVPLCHDFQSLAFYCCVFGFTIGAYVGLTSVILVDLLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMYDLTDSYAPAFLMAGLMIAISGLVMFAIPPLQRLQVRKSERKPHTEHLALS", "length": 626, "header": "tr|Q9W509-1|Q9W509_DROME Isoform 1 of Monocarboxylate transporter 1, isoform A OS=Drosophila melanogaster OX=7227 GN=Mct1 PE=1 SV=2 CANONICAL=Q9W509-1" }, "isoforms": [ { "isoform_ac": "Q9W509-1", "url": "https://www.uniprot.org/uniprotkb/Q9W509/entry#Q9W509-1", "sequence": { "sequence": "MVHGPPARRKSQQQHEACEMDMERQPTPPDGGWGWVVVFGSFMIHIVTDGMTYSFGIFYNEFLDYFNEGKGYTAWIASIMVGVTFSSGPISSSFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGFGTGLGFGLIYLPAIVSVTQYFEAKRSLATGIAVCGSGFGTFVFAPLTEFLIGNYGWRGAMLIIGGIVLNCIIFGAMFRPLELEAPPQTPPNTPSTPKLAKKSAIIDQNTTAAELEPLKVLPKDQYLQLPQRTDTAVSGGALCRSNSVGHNLKPNLNNNSNGAVNGQGPTLVTPPQAVVKSTSNDDIARKCHSQLQLTPLRDAHRERSASGTMYRPDALYQGSLHNLPDYVSSRNDLSRSMSGSGVIKRYGSLRQSNNVSQSQEEAKCCGCITCSKETRDTFAEMMNFSLLKDMVFVIFSVSNFCTSIGFNVPYLYVVAYAETLKLTKTDASYLISTIGVANTVGRIILGYISDKPWVNRLLVYNVCLTACGVSTAMVPLCHDFQSLAFYCCVFGFTIGAYVGLTSVILVDLLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMYDLTDSYAPAFLMAGLMIAISGLVMFAIPPLQRLQVRKSERKPHTEHLALS", "length": 626, "header": "tr|Q9W509-1|Q9W509_DROME Isoform 1 of Monocarboxylate transporter 1, isoform A OS=Drosophila melanogaster OX=7227 GN=Mct1 PE=1 SV=2 CANONICAL=Q9W509-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 104, "start_aa": "Thr", "end_pos": 104, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr104", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W509", "url": "https://www.uniprot.org/uniprotkb/Q9W509" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W509", "url": "https://www.uniprot.org/uniprotkb/Q9W509" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W509", "url": "https://www.uniprot.org/uniprotkb/Q9W509" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W509", "url": "https://www.uniprot.org/uniprotkb/Q9W509" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W509", "url": "https://www.uniprot.org/uniprotkb/Q9W509" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W509", "url": "https://www.uniprot.org/uniprotkb/Q9W509" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W509", "url": "https://www.uniprot.org/uniprotkb/Q9W509" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W509", "url": "https://www.uniprot.org/uniprotkb/Q9W509" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W509", "url": "https://www.uniprot.org/uniprotkb/Q9W509" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W509", "url": "https://www.uniprot.org/uniprotkb/Q9W509" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W509", "url": "https://www.uniprot.org/uniprotkb/Q9W509" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG3456", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3456", "resource": "KEGG Pathway" }, { "id": "R-DME-210991", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-210991", "resource": "Reactome", "description": "Basigin interactions" }, { "id": "R-DME-433692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-433692", "resource": "Reactome", "description": "Proton-coupled monocarboxylate transport" }, { "id": "R-DME-9749641", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9749641", "resource": "Reactome", "description": "Aspirin ADME" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0B4LFF4-1", "protein_name": "Tarag, isoform D", "gene_name": "Targ", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSRNRRRSFPSSQYEDKTAAAQPSGSSLRSQSLSRLDISVQNSSIYYNDTRNTRPQMVSVAVGTVSTDILNGRTSFLSLSQSHGSEVDLPSFYESFNPTFLPKLPIRRFPHMLVGASNEPEISKNQPAIPPSRPIEPISEVPFVEPAFEKKYSRTRGFSKELSTHRDNENEYIESTDEVSQMLSFTSYTDEYDRAEPLITKTQKFYKKRSPLIPKYDSEDSYVVPKETDQQESGLSFNVTTVQLADTASPESFSEYDGNRTRKQSFDMESKNSKESFDFSRGGRRLGSGMVFIYMVIPPDGGFGWVIMVLSFLAQLIIDGLIFTIGVLLPSIAQDLDVSISSVSFVASVQIGCYFTSGAFSAVLINRFGFRKVAIAGVLCSAVSILASSWSVSLTMLIFFYSVLACAGGITLSMIWASSQLIVGYYFERYRPMANGFSCSGGGAGIVLFTFLNSWLVPIIGWRNMLRTQAGLIMLILLMVVAYVEVAPTQVGMYHLPGSSDTSSDEYYGNFYVHDYLRQSAMTAKSRSILSTYEPRPKKKGCAKFCPSCSNCCWRRRKKSQNADEQNLLIRPAPLEREDLFYTGPAEYEKPHSKENVDGKEFLLMGSDKNTQQVNYGIKNIRVDDEPDRISRVHRERRWSNENQKKQNSCRNSRFMLTVLKLFDYRLLKQFEFKILVASAFLFPMGFNIPFVYSSARTTIPVEYARMIGPIIGISNLVMRNILGILAYKRRSWTLGLCGCGLIFGGVSVLISAFYGENLIWFQFLYGFSYAVAPAVYSTLRGLIYVKYLGLSKLTNAFGITSLAMGMGAFIGTTIAGKLIGITGNYSAAFCFAGLCLIVSGFLKLLLPLLIKCRNRMAQ", "length": 859 }, "evidence": [ { "id": "MGI:2385183", "url": "https://alliancegenome.org/gene/MGI:2385183#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070112-602", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070112-602#orthology", "database": "AGR" }, { "id": "HGNC:10925", "url": "https://alliancegenome.org/gene/HGNC:10925#orthology", "database": "AGR" }, { "id": "RGD:1359655", "url": "https://alliancegenome.org/gene/RGD:1359655#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A0A8I6ARJ5-1", "protein_name": "Monocarboxylate transporter 11", "gene_name": "Slc16a11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRGQRAGQGLQPGSSCVRSRRQVRGREPRGAERRGERRGAATRHPHSPQFPIQGWGLCVDNSIPVGLGVRSRPGLGGLAVSRSPALGTHPHPHPVSQVARAPVVISVYRRERSKLGSISALASCSAEPCLPGKRGENSAEPTLALSLPPTPGEVGPGSRAHAPGDVPTLGEQPEAGSQGRQLPSRGPGVETSFTGVSPPQQTAMTPKPAGPPDGGWGWVVAAAAFAVNGLSYGLLRSLGLALPDLAEHFERSAQDTAWVSALALAVQQAASPVGSALSTRWGARPVVMVGGVLTSLGLVFSAFARSLLHLYLGLGLLAGSGWALVFAPALGTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQFLLDTFGWRGALLLLGAVTLHLTPCGALLRPLALSGDPLAPPRTPLAALGLGLFRRPAFSVFALGTALIGGGYFVPYVHLGPHALDQGMGGYGAALVVAVAAVGDASARLVSGWLADQGWVPLPRLLVVFGSLTGLGVLAVGLVPTVGTEEGWGAPLLAAAGAYGLSAGSYAPLVFGVLPGLVGIGGVVQATGLVMMLMSLGGLLGPPLSGFLRDKTGDFSASFLVCSSFILSGSFIYMGLPRALPSCRPASPPATPPPERGELLPVPQVSLLSTGGSSSIRDTTC", "length": 650 }, "evidence": [ { "id": "MGI:2663709", "url": "https://alliancegenome.org/gene/MGI:2663709#orthology", "database": "AGR" }, { "id": "HGNC:23093", "url": "https://alliancegenome.org/gene/HGNC:23093#orthology", "database": "AGR" }, { "id": "FB:FBgn0023549", "url": "https://alliancegenome.org/gene/FB:FBgn0023549#orthology", "database": "AGR" }, { "id": "RGD:1311125", "url": "https://alliancegenome.org/gene/RGD:1311125#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M1N837-1", "protein_name": "Monocarboxylate transporter 2", "gene_name": "slc16a7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPPSASTNLGYTPPDGGWGWAVVFGSFISIGFSYAFPKSLTIYFKEIQEYFSISYSQIAWVSSIMLATMYAGGPVSSILVNRYGSRPVVIAGGLMVGVAMVTASFGTSILHLYLCVGVIGGFGLAFNLQPALTIIGKYFLVKRPMANGIAMAGSPVFLSTLAPVNQFLFDQFGWRGSFFILGGVLFNCCVAGSLMRPIKIPVSKTTEDNISPQTAGQDESKPSGCSSKLNQFIDISLFKHRGFLIYLVGNVLMFFGFFAPVVFLAPYAKHQGVDEYSAAFLLSIFALVDMFARPGTGLVANTKWIRPKIQYFFSFAVTYNGLCHLMCPLLPGYIDLVVYAVLFGLAFGMVCALLFEVLMDLVGAQRFSSAVGLATIIECGPVLLGPPISGLLVDIFMDYKYMYFACGMMMLAGGVFLFIMNYYNYRWLKKEEKQRNAEELQIFSTKELAAIDEEIKLSIEEKLKD", "length": 465 }, "evidence": [ { "id": "FB:FBgn0023549", "url": "https://alliancegenome.org/gene/FB:FBgn0023549#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-051113-248", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-051113-248#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1QL69-1", "protein_name": "Monocarboxylate transporter 13", "gene_name": "slc16a13", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEKPQKTEEEQRPCPQGAAPDGGWGWVVVGALFVISALVFGLIRSLGVFFVEFVQYFDESAQAVSWITSIGLAMQQLMSPIGAAASNVYGTRPVVMMGGFLSGLGFILASQATSLLHLYLTMGLISGLGWALVFTPTMASVMQYFTKRRSLAMGLGFTGVGLASFAFSPLFQYLVEAYAWRGALLILGGLSFNMVACGALIRPLGTPKVAVKTENSTKLNKCSFLLSRIYECFELSLLTHRGFVTYAVAITFFNAGYFIPYVHLVAHSRHIGFTEYQAAFVISITGVADIVGRVASGWASDLGKIRLLHMLVVWTGLLGLSLMLIPVAVVYAGLLLVSIVYGFCAGAMAPLAFAVVPEIVGIERVLGALGLLQLIESAGGLLGAPLSGWLKDSTGTYTVSFIAAGSFLMIGMLIAMTLPYFWSCTAPPAPSPSKKKSQEGSAEDGLIGESTSSNAINETLCSGDHIPYSDEEVKVCLSNDATHSVQEQEEIPQEMTHRSNFA", "length": 502 }, "evidence": [ { "id": "MGI:2663709", "url": "https://alliancegenome.org/gene/MGI:2663709#orthology", "database": "AGR" }, { "id": "HGNC:23093", "url": "https://alliancegenome.org/gene/HGNC:23093#orthology", "database": "AGR" }, { "id": "HGNC:31037", "url": "https://alliancegenome.org/gene/HGNC:31037#orthology", "database": "AGR" }, { "id": "RGD:1311125", "url": "https://alliancegenome.org/gene/RGD:1311125#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M2BBA0-1", "protein_name": "Monocarboxylate transporter 4-like", "gene_name": "slc16a3a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGGVALDDGGCKVKAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIREFGVGYSDTAWISSILLAMLYGTGPLCSILVNRFGCRPVMLVGGLFASLGMILASFATSIIHIYLCTGVITGLGMALNFQPSLIMLNRYFSEKRPLANGLAAAGSPVALCCLSPLGQVLQYEYGWRGGFLILGGILLNCCACGALMRPLVPPKSSEAPGIENAPDDGDKTVKPKPKLLDFSVFRDRGFLIYTIAASIMVLGLFVPPVFVVSYAKELGNEDTKSALLLSILGFIDIFARPTCGIIAGLQWVRPRCVYLFSFALIFNGITDLVGSLSKDYTSLVVFCIFFGISYGMVGALQFEVLMAVVGTEKFSSAIGLVLMLEAIAVLVGPPSAGRLLDHTKKYMFVFLLAGIEVVLSALVLAICNFLCIKKKPEAPDAAAVESGEPVEEKNHSSPPATEEPHTPNGNSEKPKTDLRPENVTEEPTEEETFLKEEDEKEKTITCSAESDL", "length": 501 }, "evidence": [ { "id": "MGI:1933438", "url": "https://alliancegenome.org/gene/MGI:1933438#orthology", "database": "AGR" }, { "id": "FB:FBgn0023549", "url": "https://alliancegenome.org/gene/FB:FBgn0023549#orthology", "database": "AGR" }, { "id": "RGD:620603", "url": "https://alliancegenome.org/gene/RGD:620603#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061009-16", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061009-16#orthology", "database": "AGR" }, { "id": "HGNC:10924", "url": "https://alliancegenome.org/gene/HGNC:10924#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9P097-1", "protein_name": "Monocarboxylate transporter 9", "gene_name": "slc16a9a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAAVKSESTLDGGWGWMIVVASFMAQFLSFGSPQSVGVLYPEWLSAFQEGKGMTAWVGSMVSGVALITSPVCSACVDNFGARPVTIFSGVMVAGGLMLSAFAPNISFLIFSYGIVVGMGCGLVYAATLTITCQYFDKRRGLALGIVTTGTSVGGFIYATLQNELIELFGLEGCLLIIGALALNLMACAGPMRPLNLPGYYLKQRAALQRTEDPEPLYSKPTAIIIESGSDLKTKPGLAENTTTVKLLINKDPTELQDSEGERKVHILSSSIIARAIKKWMRPYGQYFCETVELLQDRVFMAFCIAMFLFSLGAFPPVLFMEDVAQSEGLIDGIALIPLVSIVAMTTGIGKLILGVLADMRWVNSLYLYALTLIGSGTALLLIPVSKSYLGLQILSAAVGFFSGNWSLTSYITTKIVGIERLGQAHGILMCFGGFGIALGPPVVGWFFDWTQSYDLAFYLSGTCVLVSGVFLFLAALPCWNRTAQEGNSQAEEDVNTSQQHHSFDCDKVASVA", "length": 512 }, "evidence": [ { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PFG6-1", "protein_name": "Monocarboxylate transporter 13", "gene_name": "si:dkey-246g23.4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MERKRGTAGPAGPPLDGGYGWFIVLSTFLVFGLTFGVIKSFGVFFVEIHHYFSTTATASSWITSISVATVHIGAPVGSALSTYFGHRPVVMAGGLLSSVGMVLGSFAQDLLQLYITVGFLTGFGYALTWTPTVTMLGWYFDKRRPVANALSSTGECLLTFILTPSFQLMVDQFSWRGAMLILGALQLNLCVCGALLRPLSRHDYFKDSIEENEHELSKCSNNRADSDPMKVKVIRYVDYTLIANSRFMVYSMFGIFAALGFFAPSLFLVPYARSQGVEEYQAASLMSISAVLDLLGRVFFGWVANLRLVETVHQLIGTVVLLGAVLLLCPLATTFTQLAVFSAGYGLVFGATVAIHITVLAEVVGVERLGSALGFFMLIRSSGGLLGPPLAGIFIDKMSDYGAGFLMAGVALLVSALFLIVLHFMNKKETEHKKDICSENEEEHEDLKNRNFVFGKS", "length": 457 }, "evidence": [ { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9QAK1-1", "protein_name": "Monocarboxylate transporter 6", "gene_name": "slc16a5b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTEGVEVHQPQPNTTVTRSRASSLQAFENADTASCKSEEPDQEEEEEQSSSTLPEERHCSTGGQANAQLAPDGGWGWVVVAATILVLAMTLAFPSCIGIFYTELQSDFQASNTETSWVPAIMMAVLHACGPICSVLVERCGCRATIIIGGILSGLGMAASSFAQTMVELYITAGIITGMGFSLCFQPSITMVGHYFVRRRAFANALSSTGTALGLSILPLLANYLLRNFGWRGSFLVLGGVLLNCCVCGAVMRPLAAKPKMETRTKETDNHHLKTNCLSVHQGLKGRLRATLSTIMTFLRRHMAFDLLCSNPYFCAYALGVSWMMLGFVVPLVYLVPYATAYGMEQDQAALLMAILGLINIIVRPATALVFGLPRFRGSHNFAYLFAIAVVINGLSNCVCGIGTSFLVLLVYVILFGFSMSLVGSLLFTVLMDTVEMSRFPSALGLISIMESIMLLLGPPLAGILVDSTGQYIYVFFACSVTGSTAGLFIMLSFYWLDRRRDREQVKSSSAHQDPHSLKPSLKMTIDCEYSPVPLHSKNTRDTETDV", "length": 547 }, "evidence": [ { "id": "MGI:2443515", "url": "https://alliancegenome.org/gene/MGI:2443515#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131120-181", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131120-181#orthology", "database": "AGR" }, { "id": "FB:FBgn0023549", "url": "https://alliancegenome.org/gene/FB:FBgn0023549#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABK0LFB5-1", "protein_name": "Solute carrier family 16, member 4", "gene_name": "Slc16a4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKREEKPSPYTKPLDGGWGWMVVLHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIGWIGSIMSSLRFSAGPLAAIICDIFGEKTTSILGTFLVSGGYLISSWATGIPFLCVTMGLLPGLGSAFLYQVAAVVITKYFKKRLGLSTAIARSGMGLTFLLAPFTKLLIDLYDWTGALILFGAIALNLVPSSMLLRPVHIQSDSNSDIKNKGSILSATGPELSHKTETPNRNKAQESLIKDSAVKKSGQPTTTLTVLENQIEEISTRPHRNRPLLMSNDKTYKKKFVSWNCKEKLLDISLFRNPFFYIFTWSFLLSQLAYFIPTFHLVARAKTLGIDIMDASYLVSVAGITETVSQLISGWIADQNWIKKYQYHKAYLILCGVTNLLAPLATTFPLLMAYTIFFAIFAGGYLALILPVLVDLSKNSRVHRFLGYASFFAGMAVLSGPPIAGSHVTYAGLKLTTLEDAGFELLILLCLSPKCWNYRHVPPFLASISFPIFFNEKE", "length": 504 }, "evidence": [ { "id": "MGI:2385183", "url": "https://alliancegenome.org/gene/MGI:2385183#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070112-602", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070112-602#orthology", "database": "AGR" }, { "id": "FB:FBgn0023549", "url": "https://alliancegenome.org/gene/FB:FBgn0023549#orthology", "database": "AGR" }, { "id": "HGNC:10925", "url": "https://alliancegenome.org/gene/HGNC:10925#orthology", "database": "AGR" }, { "id": "RGD:1359655", "url": "https://alliancegenome.org/gene/RGD:1359655#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ACD6B5K3-1", "protein_name": "Monocarboxylate transporter 3 isoform X1", "gene_name": "slc16a8", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGGIVEDRETAGAPDGGWGWVVLLGGFVITGFSYAFPKAISVYFKELMHDFGCGYKDTAWISSIILAMLYGSGPISSIMVNKFGCRPVMLVGGLLASLGMISASFATSIIHLYITAGVITGLGLALNFQPSLIMLGAYFDKRRPLANGLAAAGSPVFLSALSPLGQLLLDQYGWRGGFLITGGLLLNCCTCGAVMRPLKLKERKACNQELKEMLPPEAGQENIVCENNNDKKPSKKKLLDFSVLRDKGLIIYIIAKFIVVLGLFVPTILLVNYAKDQGVPDKEAAFLLSIIGFIDIFARPTCGVVAGLKWVRPKMSYFFSLALLFNGLTDVCSATSTDYKGLIIFCVFFGLSYGMVGALQFEVLMGIVGTSKFSSALGLVLLFEAVAVLIGPPSAGYLVDKYKNYELIFYMAGGELITAGIFLALASFCCISQKKRKDSPQTQQTYVEVNPER", "length": 453 }, "evidence": [ { "id": "MGI:1929519", "url": "https://alliancegenome.org/gene/MGI:1929519#orthology", "database": "AGR" }, { "id": "FB:FBgn0023549", "url": "https://alliancegenome.org/gene/FB:FBgn0023549#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121128-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121128-1#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A1L1W9-1", "protein_name": "Monocarboxylate transporter 10", "gene_name": "slc16a10", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTEPEPTLEQEPTPEPEPTQEPTPEPTPEPEPTQEPESEPELELKQENGCTKASEQKSPEEFEPPEGGWGWVVMLASMWCNGSVFGIQNAFGIMFVYLLNEFGSEHDADLRFKTAWVGSLSMGMIFFCSPIVSVFTDLLGCRITAVGGAAVGCVGLLASSFVTSLGPMYFTYGIVFACGCSFAYQPSLVILGHYFKRRLGLVNGIVTAGSSVFTITLPYMLSGLLKSVGLYHTLRVLAIFMFILMLAGLTYKPLLPKPVSSSKPGSRCPPLSRIFNVNIWKSLGYRIWAFGIPAALYGYFVPYVHLMTHVEERFGPEANKEVLLACIGITSGVGRLIFGRVADYVPGVNKVFLQVSSFMVIGVMSMMIPLCHVFGGLIAVCLLMGLFDGCFICIMAPIAFELVGSQNVSQAIGFLLGMMSIPMTVGPPIAGFLRDRLGSYDVAFYLAGIPPLIGGAVLCAIPWVEARRKRREAANTAENTEKMLESRSPPLEDTVCRTEEPESVI", "length": 505 }, "evidence": [ { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "B1AT66-1", "protein_name": "Monocarboxylate transporter 7", "gene_name": "Slc16a6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRASGQGPQRRRRGWATRDDSAVTFRDPQPRQPAGGARALRGPDPRGPARAHQAGPLLAGARRSQHMVGGAPPRPAETGCSRSRMTQKNSKLCARANVYTQVPDGGWGWAVAVSFFFVEVFTYGIIKSFGVFFNDLMDSFDESNSKISWIISICVFVLTFTAPLSTVLSNRFGHRLVVMAGGLLISLGMITASFSQRVYHMYISIGVISGLGYCFSFLPTVTILSQYFDKRRSVVTAVASTGECFAVFAFAPAITALKEHIGWRYSLLFVGLLQLNIMVCGALLRPIIIQGPGQSPKAVTLEPRREVQYMLENEKTRTSIDSIDSGVELTTSPKNVPSEAKMEQETRAEQQQTLVTAPKHSQMKAPLLDFSVLKEKSFICYALFGLFATLGFFAPSLYIIPLGISLGIDPDRAAFLLSTMAIAEVFGRIGAGFVLNREPIRKIYIELICVILLTASLFAFTFATEFWGLMLCSVFFGSMVGTIGGTHIPMLAEDDVVGIEKMSSAAGVYVFIQSISGLAGPPLAGLLVDQSKIYSRAFYSCAAGMCLAAVCLALVRPCKKGLCQNSHSGENQTDRQRGKALQDIPEDFLEMDLGKCEHRAHMKMDPV", "length": 607 }, "evidence": [ { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D4A0E5-1", "protein_name": "Monocarboxylate transporter 14", "gene_name": "Slc16a14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYTSHEDIGYDLEDDRKAKNKKTLKPHPDIDGGWAWMMVLSSFFVHILIMGSQMALGVLNVEWLEEFHQSRGLTAWVSSLSMGITLIVGPFIGLFINTCGCRQTAIIGGLVNSLGWVLSAYAANVQSLFITFGVAAGLGSGMAYLPAVVMVGRYFQKRRALAQGLSTTGTGFGTFLMTVLLKYLCAEYGWRNAMFIQGALSLNLCVCGALMRPLSPEKVENCSGAEEPCALPAYSTESVKSGGPLDMTEEQDRRPGNEETVCDLQTQELQGQTHPRKNVCAFRVLKTVGQLTVRVQRGFRDWHSGYFGTASLFTNRMFVAFIFWALFAYSSFVIPFIHLPEIVSLYNLSEQNDAFPLTSIIAILHIFGKVILGAVADLPCISVWNVFLIANFTLVLSIFLLPLMHTYASLAVICALIGFSSGYFSLMPVVTEDLVGTEHLANAYGIIICANGISALLGPPFAGWIFDITQKYDFSFYICGLLYMVGILFLLIQPCIQMTEQSGRKCMDSAHV", "length": 512 }, "evidence": [ { "id": "MGI:1919031", "url": "https://alliancegenome.org/gene/MGI:1919031#orthology", "database": "AGR" }, { "id": "FB:FBgn0023549", "url": "https://alliancegenome.org/gene/FB:FBgn0023549#orthology", "database": "AGR" }, { "id": "HGNC:26417", "url": "https://alliancegenome.org/gene/HGNC:26417#orthology", "database": "AGR" }, { "id": "RGD:1309675", "url": "https://alliancegenome.org/gene/RGD:1309675#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A3B5-1", "protein_name": "Monocarboxylate transporter 6", "gene_name": "Slc16a5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPQALEQADGRWAWVVLLASLVTQALTVGFPSCIGVFFTDLQRDFQASNSETSWFPSIMGAMLHCGGPLCSILIKRFGCRVTMMLGGVLASLGMVASTFSDSLIHLFLTAGLITGLGMCFSFQSSITVVGLYFVRQRPLANALASIGISMGVTLWPLLARYLLETLGWRGAFLIFGGIFLHCCVCGAMLRPVATNVDPEPKEDLLLPPKTPTRSCLATCVSTIQYYLAFDILRHNMVFCIYVTGATWMTLGFSLPHIFLVPYAMHHGMEEYWAAMLMSIVGFCNIFLRPVAGMLAGRKSLAAYRKYLFAVAILINGLTNLICTVSADFRVLLGYCLVYSLSMCGTGILVFQVLMDIVPMDRFPSALGLFTILCGMGSLISPPLAGLLLDTTNNFNYVFYMSSGLLISASLFMGVGFYVAEKKLKQDRQAKMEDATSEITSKHSLTSEDKDSAKKQPYPENIYVTSV", "length": 466 }, "evidence": [ { "id": "MGI:2443515", "url": "https://alliancegenome.org/gene/MGI:2443515#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131120-181", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131120-181#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121108-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121108-4#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A734-1", "protein_name": "Monocarboxylate transporter 12", "gene_name": "Slc16a12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKITRVGSASPPDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFAQDYSQTAWIHSIVDCMTMLCAPLGSVVSNQLSCQAGIMLGGLLASTGLILGSFATSLKHLYLSLGVLTGLGFALCYSPAIAMVGKYFSRRKAFAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCGALMRPITLKEDPSGPEKSHDRDAQREDCKQASPYSPLTKEWTETRLCCSLQQGYGFLLMSDFVVLAVSVLFMAYGCSPLFVYLVPYALSVGVSHHQAAFLMSILGVIDIVGNITFGWLTDRRCLKNYRYVCYLFAVALDGLCYLCLPMLQSFPLLVPFSCTFGYFDGAYVTLIPVVTAEIVGTTSLSSALGVVYFLHAVPYLVSPPIAGWLVDTTGSYTAAFLLCGFAMIFSSILLGFAKIAKRMKRTQVPFLVKDSDPKLHLWTNGSVAYSIAKELDQKDEESLAKARTGCNLT", "length": 486 }, "evidence": [ { "id": "MGI:2147716", "url": "https://alliancegenome.org/gene/MGI:2147716#orthology", "database": "AGR" }, { "id": "HGNC:23094", "url": "https://alliancegenome.org/gene/HGNC:23094#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050522-80", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-80#orthology", "database": "AGR" }, { "id": "FB:FBgn0023549", "url": "https://alliancegenome.org/gene/FB:FBgn0023549#orthology", "database": "AGR" }, { "id": "RGD:1311468", "url": "https://alliancegenome.org/gene/RGD:1311468#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7F7B3-1", "protein_name": "Monocarboxylate transporter 1", "gene_name": "slc16a1a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAPAVGGPVGYTPPEGGWGWAVVLGAFISIGFSYAFPKSITVFFKEIEVIFNATSSQVSWISSIMLAVMYGGGPVSSILVNKYGSRPIMILGGCLSGAGLIAASFCNTVEGLYFCVGVVGGLGLAFNLNPALTMIGKYFYKKRPIANGIAMAGSPVFLSTLAPLNTWFFDQFGWRGSFLILGGLLLNCCVAGSLMRPIGPKPQPAVKADNSNSRAKERKTVVEVINGFIDLTLFKHRGFLLYLLGNVVMFFGLFSPLVFLSNYAKSKQIPREKAAFLLSILAFVDMVARPSMGIVANTKWVRPRVQHFFAASILLNGVCHLLAPLSTDYTGFVIYAIFFGFAFGWLSSVLFETLMDLVGAQRFSSAVGLVTIVECGPVLLGPPLLGKFNDIYHDYKYTYMGCGIVLLIGSLFLFVGMGINYKLLEREAKEESKKANQQDDPGKEVVEALKAAEDNAAEEAV", "length": 461 }, "evidence": [ { "id": "FB:FBgn0023549", "url": "https://alliancegenome.org/gene/FB:FBgn0023549#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110408-16", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110408-16#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FB53-1", "protein_name": "Monocarboxylate transporter 6", "gene_name": "slc16a5a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAPQQPSSMEEQSGELCEPESEELEKQGPGPPSNANAPDSYDAPDGGWGWVVLLATIIVLALTLAFPSCIIIFYLDLQKEFEATNSQTSWVPSIMTAVLHAGGPLCSVLVDRFGCRATVMFGGVLSGFGMAVSSFSHSIVDLYITAGVITGLGFCFSFQPAVTILGHYFVRRRPFANAMSSTGTALGLSTLPFLCDFLKIELGWRGSFLVLGAVLLNCCVCGAVMRPIRPRKPRKTNEINNSPKTSDKKGCMLGICQSLASSLRQQMAFDLFCSNTRFRVFSLGITWMMLGFVVPLIYLVPYASADDMDPSRAALLLSILGFVNIFVRPPVGVLFSLPWFKGRHIYVFSAALLINGLSNSICCISASFPVLLVYVLTYGLSMSVVGSLMFTVLMDTVEMSRFPSALGLLSIMESVTLLIGPPLAGFLVDRTQLYTYVFMACTIIVVLSALFLMFTFYWLDSRDAAKKDSPAKPAINISTDCQYSSVPIDGDKTNKPSSETENTTCV", "length": 506 }, "evidence": [ { "id": "MGI:2443515", "url": "https://alliancegenome.org/gene/MGI:2443515#orthology", "database": "AGR" }, { "id": "FB:FBgn0023549", "url": "https://alliancegenome.org/gene/FB:FBgn0023549#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121108-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121108-4#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1Q7T3-1", "protein_name": "Monocarboxylate transporter 4 isoform X1", "gene_name": "slc16a3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGGAVVDTGDSGVKAPDGGWGWAVLFGCFIITGFSYAFPKAVSVFFKELIREFGVGYSDTAWISSILLAMLYGTGPLCSILVNRFGCRPVMMVGGLFASLGMVLASFATNIIHIYLCTGVITGLGLALNFQPSLIMLNRYFSEKRPLANGLAAAGSPVALCCLSPLGQVLQYKYGWRGGFLILGGLLLNCCACGALMRPLLAPKKTSEVEEKPKETKPKPKLLDFTVFKDRGFLIYTIAASIMVLGLFVPPVFVVSYAKELGNEDTKSALLLTILGFIDIFARPTSGIIAGLKWVRPRCVYLFSFAMIFNGIADILGSFAKDYASLVVFCIFFGISYGMVGALQFEVLMAIVGTEKFSSAIGLVLLVEAIAVLVGPPGAGRLLDATKNYMYVFMLAGCEVVLSALVLAICNLLFIKRKPQQPDPPAKMEMAITETEMEELNKAPKDDQDNGGGAENEKKQAIEPETKTTSKDEVKELESIEVDSIEVENASKKVSGPNGVAVEPESSL", "length": 508 }, "evidence": [ { "id": "MGI:1933438", "url": "https://alliancegenome.org/gene/MGI:1933438#orthology", "database": "AGR" }, { "id": "FB:FBgn0023549", "url": "https://alliancegenome.org/gene/FB:FBgn0023549#orthology", "database": "AGR" }, { "id": "RGD:620603", "url": "https://alliancegenome.org/gene/RGD:620603#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-5487", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-5487#orthology", "database": "AGR" }, { "id": "HGNC:10924", "url": "https://alliancegenome.org/gene/HGNC:10924#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QW16-1", "protein_name": "Monocarboxylate transporter 5", "gene_name": "slc16a4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLPKEQHSDGKTAKTPCSELKAKVMKKEKKKVVYREPPDGGWGWMVVLHCFLVNVLVMGTLKTFGIFFVALQDEFGGSSESISWIGSIMSSLRLSGGPLASVACAKLGNRVTSIVGALFVSAGFLFSIFATSVTYLYISMGLVVGLGFALLYQATSVVIVTYFRKRLATAYSIGRSGMGLTFALAPFTQLLLDQYAWQGALLILGGLMLNLVASGMLLRPINIRHPASPISNSTIHKTEKDPLKNNMNGNTPVANGTSKSDSSPPIHKDTLIIKNPVHEQNSLPHLDLKKPTQNGVNGTDSSQTKTSPEMNGVSPVDSLLENGRTENVPENSPKVLDFSLLKNPFFCIYTWSLVFSQLAYFIPYFHLSARARNLGIDPMDASFIISVAGITETVAQLASGWVTDRNLVHKYHYHKAYLILCGVVNLLSPLATSYILLMVYAVFFAIFCGGYMALLLPVLVDLVGADKLNNSMGFSMFFVGLGCLTGPPLAGFLYDYTQTYDCSFYLAGVCYLLSSISLFLEPLARRWQARKERLETLNQELMWSNGCFCPAPQRNGVV", "length": 558 }, "evidence": [ { "id": "MGI:2385183", "url": "https://alliancegenome.org/gene/MGI:2385183#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070112-602", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070112-602#orthology", "database": "AGR" }, { "id": "FB:FBgn0023549", "url": "https://alliancegenome.org/gene/FB:FBgn0023549#orthology", "database": "AGR" }, { "id": "HGNC:10925", "url": "https://alliancegenome.org/gene/HGNC:10925#orthology", "database": "AGR" }, { "id": "RGD:1359655", "url": "https://alliancegenome.org/gene/RGD:1359655#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G5E8K6-1", "protein_name": "Monocarboxylate transporter 6", "gene_name": "Slc16a5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARALEQADGRWAWVVLLSSLVTQALTLGFPTCIGVFFTDLQRDFQASNSETSWFPSILGAMVHGGGPLCSILVKHFGCRVTMMLGGVLASLGMVVSTFSGSLTHLFLTAGVITGLGMCFSFQSSITVVGLYFVRRRPLANALASMGLSMGVTLWPLLARYLLETLGWRGAFLIFGGILLHCCVCGALLRPVATNEVPEPKEDPLLPPKIPTRSCLATCVSTIRYHLAFDILRHNMGFCIYVTGVTWMNLGFALPHIFLVPYAMHHGVDDYWAAMLMSIVGFCNIFLRPMAGLLLAGRKSLAAYRKYLFAVAILINGLTNLICTVSADFRVLLGYCLVYSLSMCGVGILVFQVLMDIVPMDRFPSALGLFTILCGVTSLISPPLAGLLLDKTNNFSYVFYMSSGFLVSGSLILGVGFYAAEKKKLKQDGQAKMENATSEMTPMHDLTSEDKDSAKKQPYPESIYMTNV", "length": 468 }, "evidence": [ { "id": "MGI:2443515", "url": "https://alliancegenome.org/gene/MGI:2443515#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131120-181", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131120-181#orthology", "database": "AGR" }, { "id": "FB:FBgn0023549", "url": "https://alliancegenome.org/gene/FB:FBgn0023549#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121108-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121108-4#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G8XYX6-1", "protein_name": "Monocarboxylate transporter 8", "gene_name": "slc16a2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MHSESDDNTAGGTPGSEDPQAEESSSPAEEFEEQERKLAPEDSTVQLIHTGCTDKRPATPPGAHPGQGFVPPEGGFGWVVVFAATWCNGSIFGIQNSFGILHMMLVKHHEKQPDQASQFKVAWVGALAMGMIFFCSPVVSMFTDHFGCRKTAVCGAFVAFIGLLTSSFATTLGLWYFTYGILFGCGSSFAFQPSLVILGHYFRQRLGLANGVVTAGSSLFSMGLPVLLKKVVEPLGLPRTFQILSIFMLVQALLALAFKPLLPSGMCPMPGMALDGGPSTPESASRWQKGLAKIRRYFNVRVFSILTYRIWAFGVATAVLGYFVPYVHLLNFVKEQFGDTQREWLLLVCIGASSGVGRLLFGKIGDLIPGVKKIYMQVASFILLGVMSMMIPQCAVFEGLVVVFVLMGLCDGCFITIMAPIAFELVGPMQASQAIGYLLGLMAIPMTAGPPIAGLLHDHFGNYHVAFYLAGVPPIVGGIVMFFVPLVHQRMQKRRKETDDPSMDKMLKNCSNGDMLPGYTDMETHI", "length": 526 }, "evidence": [ { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "M0RCI4-1", "protein_name": "Monocarboxylate transporter 9", "gene_name": "Slc16a9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGFQKSPDGGWGWVIVVVSFFTQFLCYGSPLAVGVLYVEWLDAFGEGKGKTAWVGSLASGVGLLASPVCSLFVSSFGARPVTIFSGFLVAGGLMLSSLAPNIYFLFFSYGIVVGLGCGLLYTATVTITCQYFDSRRGLALGLISTGSSVGLFIYAALQRMLIEFYGLDGCLLIVGALALNILACGSLMRPLQTSDCPFPEKIAPENVPDRYSIYNEKEKNQEETMTFQDKGYSNEDKCLPNGDWGRETSLPKNPTGAAHTKEPEPYKKKVVEQTNFCKQLAKRKWQVYRNYCGETASLFKNKVFSALFVAILLFDIGGFPPSLLMEDVARSYHVREEDLTIPLISIFGIMTAVGKLLLGILADFKWVNTLYLYVATLIITGLALCAIPLAKSYVTLAILSGILGFLTGNWSIFPYVTTKTVGIDKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGFCVLLGGFILLLAILPCWGMCNQRLPKPAAPTTFFYKVASNV", "length": 508 }, "evidence": [ { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O15374-1", "protein_name": "Probable monocarboxylate transporter 5", "gene_name": "SLC16A4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLKREGKVQPYTKTLDGGWGWMIVIHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIGWIGSIMSSLRFCAGPLVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLLPGLGSAFLYQVAAVVTTKYFKKRLALSTAIARSGMGLTFLLAPFTKFLIDLYDWTGALILFGAIALNLVPSSMLLRPIHIKSENNSGIKDKGSSLSAHGPEAHATETHCHETEESTIKDSTTQKAGLPSKNLTVSQNQSEEFYNGPNRNRLLLKSDEESDKVISWSCKQLFDISLFRNPFFYIFTWSFLLSQLAYFIPTFHLVARAKTLGIDIMDASYLVSVAGILETVSQIISGWVADQNWIKKYHYHKSYLILCGITNLLAPLATTFPLLMTYTICFAIFAGGYLALILPVLVDLCRNSTVNRFLGLASFFAGMAVLSGPPIAGWLYDYTQTYNGSFYFSGICYLLSSVSFFFVPLAERWKNSLT", "length": 487 }, "evidence": [ { "id": "MGI:2385183", "url": "https://alliancegenome.org/gene/MGI:2385183#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070112-602", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070112-602#orthology", "database": "AGR" }, { "id": "FB:FBgn0023549", "url": "https://alliancegenome.org/gene/FB:FBgn0023549#orthology", "database": "AGR" }, { "id": "HGNC:10925", "url": "https://alliancegenome.org/gene/HGNC:10925#orthology", "database": "AGR" }, { "id": "RGD:1359655", "url": "https://alliancegenome.org/gene/RGD:1359655#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O15375-1", "protein_name": "Monocarboxylate transporter 6", "gene_name": "SLC16A5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPQALERADGSWAWVVLLATMVTQGLTLGFPTCIGIFFTELQWEFQASNSETSWFPSILTAVLHMAGPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQSSITVLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGAIIRPVATSVAPETKECPPPPPETPALGCLAACGRTIQRHLAFDILRHNTGYCVYILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAGLMAGRPAFASHRKYLFSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIFQVLMDIVPMDQFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSFFLISAALFMGGSFYALQKKEQGKQAVAADALERDLFLEAKDGPGKQRSPEIMCQSSRQPRPAGVNKHLWGCPASSRTSHEWLLWPKAVLQAKQTALGWNSPT", "length": 505 }, "evidence": [ { "id": "MGI:2443515", "url": "https://alliancegenome.org/gene/MGI:2443515#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131120-181", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131120-181#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121108-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121108-4#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O15403-1", "protein_name": "Monocarboxylate transporter 7", "gene_name": "SLC16A6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTQNKLKLCSKANVYTEVPDGGWGWAVAVSFFFVEVFTYGIIKTFGVFFNDLMDSFNESNSRISWIISICVFVLTFSAPLATVLSNRFGHRLVVMLGGLLVSTGMVAASFSQEVSHMYVAIGIISGLGYCFSFLPTVTILSQYFGKRRSIVTAVASTGECFAVFAFAPAIMALKERIGWRYSLLFVGLLQLNIVIFGALLRPIFIRGPASPKIVIQENRKEAQYMLENEKTRTSIDSIDSGVELTTSPKNVPTHTNLELEPKADMQQVLVKTSPRPSEKKAPLLDFSILKEKSFICYALFGLFATLGFFAPSLYIIPLGISLGIDQDRAAFLLSTMAIAEVFGRIGAGFVLNREPIRKIYIELICVILLTVSLFAFTFATEFWGLMSCSIFFGFMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYIFIQSIAGLAGPPLAGLLVDQSKIYSRAFYSCAAGMALAAVCLALVRPCKMGLCQHHHSGETKVVSHRGKTLQDIPEDFLEMDLAKNEHRVHVQMEPV", "length": 523 }, "evidence": [ { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O15427-1", "protein_name": "Monocarboxylate transporter 4", "gene_name": "SLC16A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGGAVVDEGPTGVKAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDTAWISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALNFQPSLIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLNCCVCAALMRPLVVTAQPGSGPPRPSRRLLDLSVFRDRGFVLYAVAASVMVLGLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGFVAGLGKVRPYSVYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTHKFSSAIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSSLILLLGNFFCIRKKPKEPQPEVAAAEEEKLHKPPADSGVDLREVEHFLKAEPEKNGEVVHTPETSV", "length": 465 }, "evidence": [ { "id": "MGI:1933438", "url": "https://alliancegenome.org/gene/MGI:1933438#orthology", "database": "AGR" }, { "id": "FB:FBgn0023549", "url": "https://alliancegenome.org/gene/FB:FBgn0023549#orthology", "database": "AGR" }, { "id": "RGD:620603", "url": "https://alliancegenome.org/gene/RGD:620603#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061009-16", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061009-16#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-5487", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-5487#orthology", "database": "AGR" }, { "id": "HGNC:10924", "url": "https://alliancegenome.org/gene/HGNC:10924#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O35308-1", "protein_name": "Monocarboxylate transporter 3", "gene_name": "Slc16a8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGAGGPRRGAGPPDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRELKRDFGAGYSDTAWVSSIMLAMLYGTGPLSSILVTRFGCRPVMLAGGLLASAGMILASFASRLVELYLTAGVLTGLGLALNFQPSLIMLGLYFERRRPLANGLAAAGSPVFLSMLSPLGQLLGERFGWRGGFLLFGGLLLHCCACGAVMRPPPGPPPRRDPSPHGGPARRRRLLDVAVCTDRAFVVYVVTKFLMALGLFVPAILLVNYAKDAGVPDAEAAFLLSIVGFVDIVARPACGALAGLGRLRPHVPYLFSLALLANGLTDLISARARSYGTLVAFCIAFGLSYGMVGALQFEVLMATVGAPRFPSALGLVLLVEAVAVLIGPPSAGRLVDALKNYEIIFYLAGSEVALAGVFMAVTTYCCLRCSKNISSGRSAEGGASDPEDVEAERDSEPMPASTEEPGSLEALEVLSPRAGSPEQEPEEEAVPELDHESIGGHEARGQKA", "length": 492 }, "evidence": [ { "id": "MGI:1929519", "url": "https://alliancegenome.org/gene/MGI:1929519#orthology", "database": "AGR" }, { "id": "FB:FBgn0023549", "url": "https://alliancegenome.org/gene/FB:FBgn0023549#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121128-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121128-1#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O35910-1", "protein_name": "Monocarboxylate transporter 4", "gene_name": "Slc16a3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGGAVVDEGPTGIKAPDGGWGWAVLFGCFIITGFSYAFPKAVSVFFKELMHEFGIGYSDTAWISSILLAMLYGTGPLCSMCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQIYLTTGVITGLGLALNFQPSLIMLNRYFNKRRPMANGLAAAGSPVFLCALSPLGQLLQDHYGWRGGFLILGGLLLNCCVCAALMRPLVAPQASGGAEPHGPQRPSPRLLDLSVFRDRGFLIYAVAASIMVLGLFVPPVFVVSYAKDMGVPDTKAAFLLTILGFIDIFARPTAGFITGLKKVRPYSVYLFSFAMFFNGFTDLTGSTASDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTQKFSSAIGLVLLLEAVAVLIGPPSGGKLLDATKVYKYVFILAGAEVLTSSLVLLLGNFFCIGKRKRPEVTKPEEVASEEEKLHKPPVDVRVDSREVEHFLKAEPEKNGEVVHTPETSV", "length": 471 }, "evidence": [ { "id": "MGI:1933438", "url": "https://alliancegenome.org/gene/MGI:1933438#orthology", "database": "AGR" }, { "id": "FB:FBgn0023549", "url": "https://alliancegenome.org/gene/FB:FBgn0023549#orthology", "database": "AGR" }, { "id": "RGD:620603", "url": "https://alliancegenome.org/gene/RGD:620603#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061009-16", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061009-16#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-5487", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-5487#orthology", "database": "AGR" }, { "id": "HGNC:10924", "url": "https://alliancegenome.org/gene/HGNC:10924#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O60669-1", "protein_name": "Monocarboxylate transporter 2", "gene_name": "SLC16A7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPPMPSAPPVHPPPDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAWISSIMLAVMYAGGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPALTIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLILGSLLLNACVAGSLMRPLGPNQTTSKSKNKTGKTEDDSSPKKIKTKKSTWEKVNKYLDFSLFKHRGFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAFVDMFARPSVGLIANSKYIRPRIQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGSVSSVLFETLMDLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCGAIVVAASVWLLIGNAINYRLLAKERKEENARQKTRESEPLSKSKHSEDVNVKVSNAQSVTSERETNI", "length": 478 }, "evidence": [ { "id": "MGI:1330284", "url": "https://alliancegenome.org/gene/MGI:1330284#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-051113-248", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-051113-248#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O70324-1", "protein_name": "Monocarboxylate transporter 8", "gene_name": "Slc16a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALPSPASEEAEGPCQEANQEYQEPVCSPVPEPEPEPEPEPEPDPEPVPVPPPEPQPEPEPQPLPDPAPLPELGFEAEPVQEPEPTPTVETRGTARGFQPPEGGFGWIVVFAATWCNGSIFGIHNSVGILYSMLLEEEKEKNRQVEFQAAWVGALAMGMIFFCSPIVSIFTDRLGCRITATTGAAVAFIGLHTSSFTSSLSLRYFTYGILFGCGCSFAFQPSLVILGHYFQRRLGLANGVVSAGSSIFSMSFPFLIKMLGDKIKLAQTFQVLSTFMFVLTLLSLTYRPLLPSSQDTPSKRGAHTLRQRFLVQFRKYFNMRVFRQRTYRIWAFGIAAAALGYFVPYVHLMKYVEDKFKEIKETWVLLVCIGATSGLGRLVSGHISDSIPGLKKIYLQVLSFLLLGLMSMMIPLCRDFGGLIVVCLFLGLCDGFFITIMAPIAFELVGPMQASQAIGYLLGMMALPMIAGPPIAGLLRNCFGDYHVAFYFAGVPPIIGAVILFFVPLMHQRMFKKEQRDSSKDKMLSHDPDPNGELLPGSPTPEEPI", "length": 545 }, "evidence": [ { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O70451-1", "protein_name": "Monocarboxylate transporter 2", "gene_name": "Slc16a7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPSEPSAPLPQPLPPDGGWGWVVVCASFISIGFSYAFPKAVTVFFKDIQEIFNTTSSQIAWISSIMLAVMYAGGPISSVLVNNYGSRPVVIVGGLLCCIGMILASYSNSVIELYLTVGFIGGLGLAFNLQPALTIIGKYFYRRRPLANGCAMAGSPVFLSTLAPFNQYLFNNYGWKGSFLILGGIFLHSCVAGCLMRPVGPSPNTKKSKSKVGSRHDSTLKKASKVSTAQKVNRFLDFSLFMHRGFLIYLSGNVILFLGIFAPIIFLAQYAKHIGVDDYNSAFLLSVMAFIDMFARPSVGLIANTSLIRPRIQYLFSSAIIFTGICHLLCPLATTYSALVVYVVFFGLGFGSISSLLFECLMDIVGATRFSSAVGLTTIVECCPVLFGPPLAGKLLDITGEYKYLYIASGTVVLVSGTYLLIGNAINYRLLDKERKREKAKKKKSASHASREMEALNRSKQDEVTVKASNAHNPPSDRDKESNI", "length": 484 }, "evidence": [ { "id": "MGI:1330284", "url": "https://alliancegenome.org/gene/MGI:1330284#orthology", "database": "AGR" }, { "id": "FB:FBgn0023549", "url": "https://alliancegenome.org/gene/FB:FBgn0023549#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O70461-1", "protein_name": "Monocarboxylate transporter 3", "gene_name": "Slc16a8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGAGGPRRGAGPPDGGWGWVVLGACFVITGFAYGFPKAVSVFFRELKRDFGAGYSDTAWVSSIMLAMLYGTGPLSSILVTRFGCRPVMLAGGLLASAGMILASFASRLLELYLTAGVLTGLGLALNFQPSLIMLGLYFERRRPLANGLAAAGSPVFLSTLSPLGQLLGERFGWRGGFLLFGGLLLHCCACGAVMRPPPGPQPRPDPAPPGGRARHRQLLDLAVCTDRTFMVYMVTKFLMALGLFVPAILLVNYAKDAGVPDAEAAFLLSIVGFVDIVARPACGALAGLGRLRPHVPYLFSLALLANGLTDLISARARSYGTLVAFCIAFGLSYGMVGALQFEVLMATVGAPRFPSALGLVLLVEAVAVLIGPPSAGRLVDALKNYEIIFYLAGSEVVLAGVFMAVTTYCCQRCSKDIPPGPSAEGGTSDTEDVEAERDSEPMPASTEEPGSLEALEVLSPRAGSPEPEEEAVPDLSHESVGGHEAHGQNA", "length": 490 }, "evidence": [ { "id": "MGI:1929519", "url": "https://alliancegenome.org/gene/MGI:1929519#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121128-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121128-1#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O95907-1", "protein_name": "Monocarboxylate transporter 3", "gene_name": "SLC16A8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGAGGPRRGEGPPDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRALMRDFDAGYSDTAWVSSIMLAMLYGTGPVSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLTGLGLALNFQPSLIMLGLYFERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFLLLGGLLLHCCACGAVMRPPPGPGPRPRRDSAGDRAGDAPGEAEADGAGLQLREASPRVRPRRRLLDLAVCTDRAFAVYAVTKFLMALGLFVPAILLVNYAKDAGVPDTDAAFLLSIVGFVDIVARPACGALAGLARLRPHVPYLFSLALLANGLTDLSSARARSYGALVAFCVAFGLSYGMVGALQFEVLMAAVGAPRFPSALGLVLLVEAAAVLIGPPSAGRLVDVLKNYEIIFYLAGSEVALAGVFMAVATNCCLRCAKAAPSGPGTEGGASDTEDAEAEGDSEPLPVVAEEPGNLEALEVLSARGEPTEPEIEARPRLAAESV", "length": 504 }, "evidence": [ { "id": "MGI:1929519", "url": "https://alliancegenome.org/gene/MGI:1929519#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121128-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121128-1#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P36032-1", "protein_name": "Probable transporter MCH2", "gene_name": "MCH2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSEERHEDHHRDVENKLNLNGKDDINGNTSISIEVPDGGYGWFILLAFILYNFSTWGANSGYAIYLAHYLENNTFAGGSKLDYASIGGLAFSCGLFFAPVITWLYHIFSIQFIIGLGILFQGAALLLAAFSVTLWEIYLTQGVLIGFGLAFIFIPSVTLIPLWFRNKRSLASGIGTAGSGLGGIVFNLGMQSILQKRGVKWALIAQCIICTSLSTIALMLTRTTHQGLRQHKRSYKFELLDYDVLSNFAVWLLFGFVSFAMLGYVVLLYSLSDFTVSLGYTSKQGSYVSCMVSVGSLLGRPIVGHIADKYGSLTVGMILHLVMAILCWAMWIPCKNLATAIAFGLLVGSIMGTIWPTIASIVTRIVGLQKLPGTFGSTWIFMAAFALVAPIIGLELRSTDTNGNDYYRTAIFVGFAYFGVSLCQWLLRGFIIARDEIAVREAYSADQNELHLNVKLSHMSKCLFRYKQLPRRV", "length": 473 }, "evidence": [ { "id": "MGI:1330284", "url": "https://alliancegenome.org/gene/MGI:1330284#orthology", "database": "AGR" }, { "id": "MGI:2443515", "url": "https://alliancegenome.org/gene/MGI:2443515#orthology", "database": "AGR" }, { "id": "MGI:1919031", "url": "https://alliancegenome.org/gene/MGI:1919031#orthology", "database": "AGR" }, { "id": "MGI:2147716", "url": "https://alliancegenome.org/gene/MGI:2147716#orthology", "database": "AGR" }, { "id": "MGI:1929519", "url": "https://alliancegenome.org/gene/MGI:1929519#orthology", "database": "AGR" }, { "id": "MGI:1933438", "url": "https://alliancegenome.org/gene/MGI:1933438#orthology", "database": "AGR" }, { "id": "MGI:2385183", "url": "https://alliancegenome.org/gene/MGI:2385183#orthology", "database": "AGR" }, { "id": "MGI:2663709", "url": "https://alliancegenome.org/gene/MGI:2663709#orthology", "database": "AGR" }, { "id": "HGNC:23093", "url": "https://alliancegenome.org/gene/HGNC:23093#orthology", "database": "AGR" }, { "id": "HGNC:23094", "url": "https://alliancegenome.org/gene/HGNC:23094#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050522-80", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-80#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070112-602", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070112-602#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131120-181", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131120-181#orthology", "database": "AGR" }, { "id": "FB:FBgn0023549", "url": "https://alliancegenome.org/gene/FB:FBgn0023549#orthology", "database": "AGR" }, { "id": "RGD:620603", "url": "https://alliancegenome.org/gene/RGD:620603#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P53918-1", "protein_name": "Uncharacterized transporter ESBP6", "gene_name": "ESBP6", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSTHSNDYFSASSGMVSETSSEVSSINSSQPVSFSKASIAAPVPCSDLHSTKSNDASRKLSISRTLTNRLNDIKKAVDDDNLQTEENSADVNKILESRFDVADAIRLQHNESVQSKLNIPVTHTTTAGASLSAPSSSAFSASSIQNDTTEHKASMDSKLMRNRLYPASTKHSGKDLEAQGITEFEPDEPTVKKVFTNKSTGQLELPPDGGYGWVVTFCVFLTMFSTWGCNASFGVDLAYYLNHDTYPGASKYDYALIAGLTVFLGQLLSPLVMALMRIIGLRTTMLFGDAVMLAAYLLASFTTKLWQLYVTQGFMVGCSISLIFVPATTVLPGWFLKKRAVAMGVSLLGTGAGGVVYGLATNKMLSDFGNTRWCLRIIGISCSISVLVAIALLKERNPTPAIGLKSPRAMFEQLKAMFSLKVITKPFVVLIALWFMFALFAYNMMVFTLSSYAISKGLSSHDASTLTAILNGSQSIGRPLMGLAGDKFGRANVTIVLTTLLTIYMFAFWIPAHTFVQLIFFSILVGSCVGVANVMNTVLIADMVKPEEFLPAWAFVNYCGAPFLLVCEVIAQALTVEKDKSNPYLHAQIFCGCCFIAALILISILREYSIRMKLTERQAMTNEKLKEWKASEYDTDSADEDWGKLKERKTKYDLLLGPGIKKYFLRMVYPMKV", "length": 673 }, "evidence": [ { "id": "MGI:1330284", "url": "https://alliancegenome.org/gene/MGI:1330284#orthology", "database": "AGR" }, { "id": "MGI:2443515", "url": "https://alliancegenome.org/gene/MGI:2443515#orthology", "database": "AGR" }, { "id": "MGI:1919031", "url": "https://alliancegenome.org/gene/MGI:1919031#orthology", "database": "AGR" }, { "id": "MGI:2147716", "url": "https://alliancegenome.org/gene/MGI:2147716#orthology", "database": "AGR" }, { "id": "MGI:1929519", "url": "https://alliancegenome.org/gene/MGI:1929519#orthology", "database": "AGR" }, { "id": "MGI:1933438", "url": "https://alliancegenome.org/gene/MGI:1933438#orthology", "database": "AGR" }, { "id": "MGI:2385183", "url": "https://alliancegenome.org/gene/MGI:2385183#orthology", "database": "AGR" }, { "id": "MGI:2663709", "url": "https://alliancegenome.org/gene/MGI:2663709#orthology", "database": "AGR" }, { "id": "HGNC:23093", "url": "https://alliancegenome.org/gene/HGNC:23093#orthology", "database": "AGR" }, { "id": "HGNC:23094", "url": "https://alliancegenome.org/gene/HGNC:23094#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070112-602", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070112-602#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131120-181", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131120-181#orthology", "database": "AGR" }, { "id": "RGD:620603", "url": "https://alliancegenome.org/gene/RGD:620603#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121108-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121108-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061009-16", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061009-16#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-5487", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-5487#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121128-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121128-1#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-051113-248", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-051113-248#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110408-16", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110408-16#orthology", "database": "AGR" }, { "id": "HGNC:31037", "url": "https://alliancegenome.org/gene/HGNC:31037#orthology", "database": "AGR" }, { "id": "HGNC:26417", "url": "https://alliancegenome.org/gene/HGNC:26417#orthology", "database": "AGR" }, { "id": "HGNC:10924", "url": "https://alliancegenome.org/gene/HGNC:10924#orthology", "database": "AGR" }, { "id": "HGNC:10925", "url": "https://alliancegenome.org/gene/HGNC:10925#orthology", "database": "AGR" }, { "id": "RGD:1311125", "url": "https://alliancegenome.org/gene/RGD:1311125#orthology", "database": "AGR" }, { "id": "RGD:1359655", "url": "https://alliancegenome.org/gene/RGD:1359655#orthology", "database": "AGR" }, { "id": "RGD:1311468", "url": "https://alliancegenome.org/gene/RGD:1311468#orthology", "database": "AGR" }, { "id": "RGD:1309675", "url": "https://alliancegenome.org/gene/RGD:1309675#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P53985-1", "protein_name": "Monocarboxylate transporter 1", "gene_name": "SLC16A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPPAVGGPVGYTPPDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSWISSIMLAVMYGGGPISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIGGLGLAFNLNPALTMIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGLLLNCCVAGALMRPIGPKPTKAGKDKSKASLEKAGKSGVKKDLHDANTDLIGRHPKQEKRSVFQTINQFLDLTLFTHRGFLLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAFLLSILAFVDMVARPSMGLVANTKPIRPRIQYFFAASVVANGVCHMLAPLSTTYVGFCVYAGFFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVVLIISGIYLFIGMGINYRLLAKEQKANEQKKESKEEETSIDVAGKPNEVTKAAESPDQKDTDGGPKEEESPV", "length": 500 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-110408-16", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110408-16#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P53986-1", "protein_name": "Monocarboxylate transporter 1", "gene_name": "Slc16a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPPAIGGPVGYTPPDGGWGWAVLVGAFISIGFSYAFPKSITVFFKEIEVIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYLCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFDIFDWRGSFLILGGLLLNCCVAGSLMRPIGPEQVKLEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTINKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSSYGKSKDFSSEKSAFLLSILAFVDMVARPSMGLAANTKWIRPRIQYFFAASVVANGVCHLLAPLSTTYVGFCVYAGVFGFAFGWLSSVLFETLMDLIGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGIYLFIGMGINYRLLAKEQKAEEKQKREGKEDEASTDVDEKPKETMKAAQSPQQHSSGDPTEEESPV", "length": 493 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-110408-16", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110408-16#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P53987-1", "protein_name": "Monocarboxylate transporter 1", "gene_name": "Slc16a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV", "length": 494 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-110408-16", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110408-16#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P57787-1", "protein_name": "Monocarboxylate transporter 4", "gene_name": "Slc16a3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGGAVVDEGPTGIKAPDGGWGWAVLFGCFIITGFSYAFPKAVSVFFKELMHEFGIGYSDTAWISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQIYLTTGVITGLGLALNFQPSLIMLNRYFNKRRPIANGLAAAGSPVFLCALSPLGQLLQDHYGWRGGFLILGGLLLNCCVCAALMRPLVAPQVGGGTEPRGPQRPPQRLLDLSVFRDRGFLIYAVAASIMVLGLFVPPVFVVSYAKDMGVPDTKAAFLLTILGFIDIFARPTAGFITGLKKVRPYSVYLFSFAMFFNGFTDLTGSTATDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTQKFSSAIGLVLLLEAVAVLIGPPSGGKLLDATKVYKYVFILAGAEVLTSSLVLLLGNFFCIGKRKRPEVTEPEEVASEEKLHKPPVDVGVDSREVEHFLKAEPEKNGEVVHTPETSV", "length": 470 }, "evidence": [ { "id": "MGI:1933438", "url": "https://alliancegenome.org/gene/MGI:1933438#orthology", "database": "AGR" }, { "id": "FB:FBgn0023549", "url": "https://alliancegenome.org/gene/FB:FBgn0023549#orthology", "database": "AGR" }, { "id": "RGD:620603", "url": "https://alliancegenome.org/gene/RGD:620603#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061009-16", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061009-16#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-5487", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-5487#orthology", "database": "AGR" }, { "id": "HGNC:10924", "url": "https://alliancegenome.org/gene/HGNC:10924#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q08268-1", "protein_name": "Probable transporter MCH4", "gene_name": "MCH4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLNIPIIANSKRFLFSKDHEAQSTRDHDVELETREGPSSGYNPNFNAADAILKKNSDQVDLDVNKLTNVTSRVLNTPEASLIYDDDREFPDGGLKAWLVVFGAFMGLVPVFGLINSLGAIESYISKHQLANISSSTISWIFSLYLAISFLSCILSGGYFDRNGSIGLMCTGTVIYAGGLFALANCKSVWQFILAFSVCSGLGTGILMTPLIGTVATWFLKRRGIATSISTMGGSIGGIVFPIMLRKLYKEVGFQWAIRILSFICLTCLICASVLARERTKPVVQPFKSKAEVAKWYISSVFNWRYFLEGKFLFVAIGASFAESSLTSCATYLASYSMTRGNTENVAYTMITASNAVGILGRYIPGYFADKFIGRFNVEIITISMAALFNFVMWLPFGGNTKVLWAYVCLWGFSTGSILSLTPVCIGQISKTTDFGKRYATVYLLQALVTIPVLPIGGTLIGKGTVANYNHFIIFNSALMAAGAACYIISRHICVGAKLCKF", "length": 501 }, "evidence": [ { "id": "MGI:1330284", "url": "https://alliancegenome.org/gene/MGI:1330284#orthology", "database": "AGR" }, { "id": "MGI:2443515", "url": "https://alliancegenome.org/gene/MGI:2443515#orthology", "database": "AGR" }, { "id": "MGI:2147716", "url": "https://alliancegenome.org/gene/MGI:2147716#orthology", "database": "AGR" }, { "id": "MGI:1929519", "url": "https://alliancegenome.org/gene/MGI:1929519#orthology", "database": "AGR" }, { "id": "MGI:1933438", "url": "https://alliancegenome.org/gene/MGI:1933438#orthology", "database": "AGR" }, { "id": "MGI:2663709", "url": "https://alliancegenome.org/gene/MGI:2663709#orthology", "database": "AGR" }, { "id": "HGNC:23093", "url": "https://alliancegenome.org/gene/HGNC:23093#orthology", "database": "AGR" }, { "id": "HGNC:23094", "url": "https://alliancegenome.org/gene/HGNC:23094#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050522-80", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-80#orthology", "database": "AGR" }, { "id": "FB:FBgn0023549", "url": "https://alliancegenome.org/gene/FB:FBgn0023549#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121108-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121108-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061009-16", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061009-16#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-5487", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-5487#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121128-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121128-1#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-051113-248", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-051113-248#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110408-16", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110408-16#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q08777-1", "protein_name": "Riboflavin transporter MCH5", "gene_name": "MCH5", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSSDSLTPKDTIVPEEQTNQLRQPDLDEDSIHYDPEADDLESLETTASYASTSVSAKVYTKKEVNKGTDIESQPHWGENTSSTHDSDKEEDSNEEIESFPEGGFKAWVVTFGCFLGLIACFGLLNSTGVIESHLQDNQLSSESVSTIGWLFSLFLFVCSASCIISGTYFDRNGFRTIMIVGTVFHVAGLFATANSTKYWHFILSFAIVCGFGNGIVLSPLVSVPAHYFFKRRGTALAMATIGGSVGGVVFPIMLRSFFSMKSDTDPTYGFVWGIRTLGFLDLALLTLSIILVKERLPHVIENSKDGESRWRYILRVYILQCFDAKAFLDMKYLFCVLGTVFSELSINSALTYYGSYATSHGISANDAYTLIMIINVCGIPGRWVPGYLSDKFGRFNVAIATLLTLFIVMFVGWLPFGTNLTNMYVISALYGFCSGSVFSLLPVCCGQISKTEEFGKRYSTMYFVVGFGTLVGIPITGAIISIKTTADYQHYIIFCGLATFVSAVCYIISRAYCVGFKWVRF", "length": 521 }, "evidence": [ { "id": "MGI:1330284", "url": "https://alliancegenome.org/gene/MGI:1330284#orthology", "database": "AGR" }, { "id": "MGI:2443515", "url": "https://alliancegenome.org/gene/MGI:2443515#orthology", "database": "AGR" }, { "id": "MGI:1919031", "url": "https://alliancegenome.org/gene/MGI:1919031#orthology", "database": "AGR" }, { "id": "MGI:2147716", "url": "https://alliancegenome.org/gene/MGI:2147716#orthology", "database": "AGR" }, { "id": "MGI:1929519", "url": "https://alliancegenome.org/gene/MGI:1929519#orthology", "database": "AGR" }, { "id": "MGI:1933438", "url": "https://alliancegenome.org/gene/MGI:1933438#orthology", "database": "AGR" }, { "id": "MGI:2663709", "url": "https://alliancegenome.org/gene/MGI:2663709#orthology", "database": "AGR" }, { "id": "HGNC:23093", "url": "https://alliancegenome.org/gene/HGNC:23093#orthology", "database": "AGR" }, { "id": "HGNC:23094", "url": "https://alliancegenome.org/gene/HGNC:23094#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050522-80", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-80#orthology", "database": "AGR" }, { "id": "FB:FBgn0023549", "url": "https://alliancegenome.org/gene/FB:FBgn0023549#orthology", "database": "AGR" }, { "id": "RGD:620603", "url": "https://alliancegenome.org/gene/RGD:620603#orthology", "database": "AGR" }, { "id": "RGD:1309675", "url": "https://alliancegenome.org/gene/RGD:1309675#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q0E960-1", "protein_name": "Major facilitator superfamily (MFS) profile domain-containing protein", "gene_name": "Dmel\\CG8389", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDVQSSRVVPDGGYGWIVVAAVALINMTNQSILSVFGQLFVGELQKMQEDTFTAALITNLNSLALNFSGLFIGPAIKSFKPRNVAATGCILVALGLALCAFASESWHFILGYSFFVGFGLGLISPSTFMAINSYFTTKRGRAVGVSLAGAGLGQVLIPHLVRYLLDNHGFRYAVLSMSSLSLFGLFGAAFLKPLNPPAKHNNRKHIRLLTEADGEKTSPLQVVIVPTNQSKIERSPPNVDTLCSRMGQRLVQAMDLELLKDLVFWSIIVGMALVYTATINFTMIFPGFLGQTAQLNSQMVAFCMSLVAGADIVFRLLLPIVTDHLRIPYRVVFLIGIVGLFVARCVLAENQTLPVIITMSVLTGMMKSATVINNNLTISAHCRSEKLAGGLGLSMMSKGVIVITVGQLLGWVRDYADSYLICLYAQGVILLVVVLVWTPEILYRHRRQRCATNKSMETQSIDAAEVAKLNS", "length": 471 }, "evidence": [ { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q3U9N9-1", "protein_name": "Monocarboxylate transporter 10", "gene_name": "Slc16a10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVPSQEEPAAERETNEAQPPGPAPSDDAPLPGPGPSDVSDVAAEKVEVELTRSAGSEPPVPPEGGWGWLVMLAAMWCNGSVFGIQNAYGVLFVSMLDTFKAKDDDNMAFKTAWVGSLSMGMIFFCCPIVSVFTDMFGCRRTAVVGAAVGFIGLMSSSFVSSIEPLYLTYGIIFACGCSFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLGNLISSVKLFNTLRILCIFMFVLFLAGFTYRPLVPSTKEKESGGSRSSFFSRRKLSPPKKVFNFALFKETTYAVWAAGIPLALFGYFVPYVHLMNHVKERFQDVNNKEVLFMCIGITSGVGRLLFGRIADYLPGVKKVYLQVLSFFFIGLMSMMIPLCSAFGALIAVCLAMGLFDGCFISIMAPIAFELVGPQDASQAIGFLLGFMSIPMTVGPPIAGLLHDKLGTYDVAFYLAGIPPFVGGVVLCLIPWIHSKKQRKISKNAGGEKMEKMLENQSSLLSGSSGIFKKDSASII", "length": 512 }, "evidence": [ { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q503M4-1", "protein_name": "Monocarboxylate transporter 12-B", "gene_name": "slc16a12b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAQEKKKGGVLPPDGGWGWMIVAGCFVVTVCTRAVTRCISIFFVEFQMHFAKDYSGTAWIHSLVDCTTMLCAPLGSLIGNQLSCRIAVILGGFLASVGLVLSSFATSLEYLYATLGLLTGLGFALCYTPAIAMVGIYFCERKALAYGIAMSGSGIGTFILAPVVQLLIEHYSWRGALLILGGFVLNLCVCGALLRPIILKEEEACPLPVDSECGYSVKPPTLNGGPTRSAASDAKQRCFQSMQEYHFLLMPDFLVLAGSFLLLASGCSLPFVYLVPYALDVGVGHQHAAFLMSILGVIDIVGNITFGWLTDRRCLKKYRNICYMFAVGMEGLCCLFIPLLRTFVWLVPFSVLYGYFDGAYVALIPVVTSDVVGRQYLSSALGVVYFLHAVPYLVSPPIGGWLVDTTGTYTATFFLSGFALISSSLLLFSVAIIRYCQRNQKKNSLSKIPKLVSCEGKQVDYYPPKNKDLMLIIPATS", "length": 477 }, "evidence": [ { "id": "MGI:2147716", "url": "https://alliancegenome.org/gene/MGI:2147716#orthology", "database": "AGR" }, { "id": "HGNC:23094", "url": "https://alliancegenome.org/gene/HGNC:23094#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050522-80", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-80#orthology", "database": "AGR" }, { "id": "FB:FBgn0023549", "url": "https://alliancegenome.org/gene/FB:FBgn0023549#orthology", "database": "AGR" }, { "id": "RGD:1311468", "url": "https://alliancegenome.org/gene/RGD:1311468#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5NC32-1", "protein_name": "Monocarboxylate transporter 11", "gene_name": "Slc16a11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTPKPAGPPDGGWGWVVAAAAFAVNGLSYGLLRSLGLALPDLAEHFERSAQDTAWVSALALAVQQAASPVGSALSTRWGARPVVMVGGVLTSLGLVFSAFARSLLHLYLGLGLLAGSGWALVFAPALGTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQFLLDTFGWRGALLLLGAVTLHLTPCGALLRPLALSGDPLAPPRTPLAALGLGLFKRRAFSVFALGTALIGGGYFVPYVHLGPHALDQGMGGYGAALVVAVAAVGDACARLASGWLADQGWVPLPRLLVVFGSLTGLGVLAMGLVPTVGTEEGWGAPLLAAAGAYGLSAGSYAPLVFGVLPGLVGIGGVVQATGLVMMLMSLGGLLGPPLSGFLRDKTGDFSASFLVCSSFILSGSFIYMGLPRALPSCRPASPPATPPPERGELLPVPQVSLLSAGGTGSIRDTTC", "length": 447 }, "evidence": [ { "id": "MGI:2663709", "url": "https://alliancegenome.org/gene/MGI:2663709#orthology", "database": "AGR" }, { "id": "HGNC:23093", "url": "https://alliancegenome.org/gene/HGNC:23093#orthology", "database": "AGR" }, { "id": "FB:FBgn0023549", "url": "https://alliancegenome.org/gene/FB:FBgn0023549#orthology", "database": "AGR" }, { "id": "RGD:1311125", "url": "https://alliancegenome.org/gene/RGD:1311125#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q63344-1", "protein_name": "Monocarboxylate transporter 2", "gene_name": "Slc16a7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPSESSVKATAAPPPFPLPPDGGWGWVVVCASFISIGFSYAFPKAVTVFFNDIKDIFKTTSSQIAWISSIMLAVMYAGGPISSVLVNNYGSRPVVIVGGLLCCTGMILASFSSSVIELYLTVGFIGGLGLAFNLQPALTIIGKYFYRKRPLANGFAMAGSPVFLSTLAPFNQFLFNSYGWKGSFLILGAIFLHSCVAGCLMRPVGPSPRAAKSKSKVGSRQDSSTKRLSKVSTAEKINRFLDFGLFTHRGFLIYLSGNVVLFLGMFAPIIFLAPYAKDKGVDDYNSAFLLSVMAFTDMFARPSVGLIANTSLIRPRIQYLFSVAIMFTGICHLLCPLAHSYTALVVYVIFFGIGFGSISSLLFECLMDQVGASRFSSAVGLVTIVECCPVLFGPPLAGKLLDITGQYKYLYIASGIVVLSSGIYLLICNAINYRLLEKERKREKARRKKSASQASKEMEALSRSKQDDVTVKVSNTHNPPSDRDKESSI", "length": 489 }, "evidence": [ { "id": "MGI:1330284", "url": "https://alliancegenome.org/gene/MGI:1330284#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q66HE2-1", "protein_name": "Monocarboxylate transporter 13", "gene_name": "Slc16a13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVHRTEPPDGGWGWMVVLSAFFQSALVFGVLRSFGVFFVEFVAAFEEQAARVSWIASIGIAVQQFGSPIGSALSTKLGPRPVVMTGGILAALGMLLASFATSLTHLYLSIGLLSGSGWALTFTPTLACLSRYFSQRRSLAMGLALTGVGISSFAFAPLFQWLLNNYAWRGALLLVSALSLHLVACGALLRPLSLTEDTAVGGPWAQITSLLCHGPFLRYTVALTLINTGYFIPYVHLVAHLQDLGWDPLPAAFLLSVAAISDLVGRVASGWLGDAVPGPVARLLMLWTTLTGVSLALFPVAQASTTLVVLAVAYGFTSGALTPVAFSVIPELVGTGRIYCGLGLVQMIESVGGLLGAPLSGYLRDVTGNYTASFVVAGAFLLAGSGVLITLPHFFSCISLSTSRPQDLVIEAPDTKIPLPKEEGLGEN", "length": 428 }, "evidence": [ { "id": "HGNC:31037", "url": "https://alliancegenome.org/gene/HGNC:31037#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6ZSM3-1", "protein_name": "Monocarboxylate transporter 12", "gene_name": "SLC16A12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPSGSHWTANSSKIITWLLEQPGKEEKRKTMAKVNRARSTSPPDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFTQDYAQTAWIHSIVDCVTMLCAPLGSVVSNHLSCQVGIMLGGLLASTGLILSSFATSLKHLYLTLGVLTGLGFALCYSPAIAMVGKYFSRRKALAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCGALMRPITLKEDHTTPEQNHVCRTQKEDIKRVSPYSSLTKEWAQTCLCCCLQQEYSFLLMSDFVVLAVSVLFMAYGCSPLFVYLVPYALSVGVSHQQAAFLMSILGVIDIIGNITFGWLTDRRCLKNYQYVCYLFAVGMDGLCYLCLPMLQSLPLLVPFSCTFGYFDGAYVTLIPVVTTEIVGTTSLSSALGVVYFLHAVPYLVSPPIAGRLVDTTGSYTAAFLLCGFSMIFSSVLLGFARLIKRMRKTQLQFIAKESDPKLQLWTNGSVAYSVARELDQKHGEPVATAVPGYSLT", "length": 516 }, "evidence": [ { "id": "MGI:2147716", "url": "https://alliancegenome.org/gene/MGI:2147716#orthology", "database": "AGR" }, { "id": "HGNC:23094", "url": "https://alliancegenome.org/gene/HGNC:23094#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050522-80", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-80#orthology", "database": "AGR" }, { "id": "FB:FBgn0023549", "url": "https://alliancegenome.org/gene/FB:FBgn0023549#orthology", "database": "AGR" }, { "id": "RGD:1311468", "url": "https://alliancegenome.org/gene/RGD:1311468#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7RTX9-1", "protein_name": "Monocarboxylate transporter 14", "gene_name": "SLC16A14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MYTSHEDIGYDFEDGPKDKKTLKPHPNIDGGWAWMMVLSSFFVHILIMGSQMALGVLNVEWLEEFHQSRGLTAWVSSLSMGITLIVGPFIGLFINTCGCRQTAIIGGLVNSLGWVLSAYAANVHYLFITFGVAAGLGSGMAYLPAVVMVGRYFQKRRALAQGLSTTGTGFGTFLMTVLLKYLCAEYGWRNAMLIQGAVSLNLCVCGALMRPLSPGKNPNDPGEKDVRGLPAHSTESVKSTGQQGRTEEKDGGLGNEETLCDLQAQECPDQAGHRKNMCALRILKTVSWLTMRVRKGFEDWYSGYFGTASLFTNRMFVAFIFWALFAYSSFVIPFIHLPEIVNLYNLSEQNDVFPLTSIIAIVHIFGKVILGVIADLPCISVWNVFLLANFTLVLSIFILPLMHTYAGLAVICALIGFSSGYFSLMPVVTEDLVGIEHLANAYGIIICANGISALLGPPFAGWIYDITQKYDFSFYICGLLYMIGILFLLIQPCIRIIEQSRRKYMDGAHV", "length": 510 }, "evidence": [ { "id": "MGI:1919031", "url": "https://alliancegenome.org/gene/MGI:1919031#orthology", "database": "AGR" }, { "id": "FB:FBgn0023549", "url": "https://alliancegenome.org/gene/FB:FBgn0023549#orthology", "database": "AGR" }, { "id": "HGNC:26417", "url": "https://alliancegenome.org/gene/HGNC:26417#orthology", "database": "AGR" }, { "id": "RGD:1309675", "url": "https://alliancegenome.org/gene/RGD:1309675#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7RTY0-1", "protein_name": "Monocarboxylate transporter 13", "gene_name": "SLC16A13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARRTEPPDGGWGWVVVLSAFFQSALVFGVLRSFGVFFVEFVAAFEEQAARVSWIASIGIAVQQFGSPVGSALSTKFGPRPVVMTGGILAALGMLLASFATSLTHLYLSIGLLSGSGWALTFAPTLACLSCYFSRRRSLATGLALTGVGLSSFTFAPFFQWLLSHYAWRGSLLLVSALSLHLVACGALLRPPSLAEDPAVGGPRAQLTSLLHHGPFLRYTVALTLINTGYFIPYLHLVAHLQDLDWDPLPAAFLLSVVAISDLVGRVVSGWLGDAVPGPVTRLLMLWTTLTGVSLALFPVAQAPTALVALAVAYGFTSGALAPLAFSVLPELIGTRRIYCGLGLLQMIESIGGLLGPPLSGYLRDVTGNYTASFVVAGAFLLSGSGILLTLPHFFCFSTTTSGPQDLVTEALDTKVPLPKEGLEED", "length": 426 }, "evidence": [ { "id": "FB:FBgn0023549", "url": "https://alliancegenome.org/gene/FB:FBgn0023549#orthology", "database": "AGR" }, { "id": "HGNC:31037", "url": "https://alliancegenome.org/gene/HGNC:31037#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TM99-1", "protein_name": "Monocarboxylate transporter 9", "gene_name": "Slc16a9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEFQKSPDGGWGWVIVVVSFFTQFLSYGSPLAVGVLYVEWLDAFGEGKGKTAWVGSLASGVGLLASPVCSLFVSSFGARPVTIFSGFLVAGGLMLSSLAPNIYFLFFSYGIVVGLGCGLLYTATVTITCQYFDSRRGLALGLISTGSSVGLFIYAALQRMLIEFYGLDGCLLIVGALALNILACGSLMRPLQTSDCPFPEKTAPENVPDRYSMYNEKEKNPEETMNFQDKGYSSEDKCLPNGDWGRETSLPKSLAIAAHTKEPETYKKKVVEQTNFCKQLAKRKWQLYRNYCGETASLFKNKVFSALFIAILLFDIGGFPPSLLMEDVARSYHVREEDLTMPLISIFGIMTAVGKLLLGILADFKWINTLYLYVATLIITGLALCAIPFAKSYVTLAILSGILGFLTGNWSIFPYVTTKTVGIDKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGFCVLLGGFILLLAILPCWDMCNKKLPKPAVPTTFFYKVASNV", "length": 508 }, "evidence": [ { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TMR7-1", "protein_name": "Monocarboxylate transporter 7", "gene_name": "Slc16a6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTQKNSKLCSRANVYTQVPDGGWGWVVAASFFFIEVFTYGVIKSFGVFFNDLMDSFDESNSKISWIISICVFIMTFTAPLSTILTNRFGHRLVVMGGGLLISVGMIAASFSQRVYQMYISIGIVSGLGYCFSFLPTVTILSQYFDKRRSMVTAVASTGECFAMFAFAPAITALKEHIGWRYSLLFVGLLQLNVMVCGALLRPIIIKGPGSPKAIPLEPRREVQYMLENEKTRTSIDSIDSGVELTTSPKNVPSEAKREQEVRVEQQQTLVVGPKHSQKRAPLLDFSILKDRSFICYTLFGLFATLGFFAPSLYIIPLGISLGIHPDRAAFLLSTMAIAEVFGRIGMGLVLNREPIRKIYIELICVILLTVSLFAFTFATEFWGLMLCSVFFGSMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYVFIQSISGLAGPPLAGLLVDQSKIYSRAFYSCAAGMALAAVCLALVRPCKKGLCQNPHSGENQTDGHRGKALQDIPEDFLEMDLGKCEPRAHMKMDPV", "length": 522 }, "evidence": [ { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BGC3-1", "protein_name": "Monocarboxylate transporter 12", "gene_name": "Slc16a12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTKITRVSLASPPDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFAQDYSQTAWIHSIVDCMTMLCAPLGSVVSNQLSCQAGIMLGGLLASTGFILGSFATSLKHLYLSLGVLTGLGFALCYSPAIAMVGKYFSRRKALAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCGALMRPITLKEDRSVPEKNHNRESQREDCKQASPYSPLTKECTETRLCCSLQQEYGFLLMSDFVVLAVSVLFMAYGCSPLFVYLVPYALSVGVSHHQAAFLMSILGVIDIVGNITFGWLTDRRCLKNYRYVCYLFAVALDGLCYLCLPMLQTFPLLVPFSCTFGYFDGAYVTLIPVVTAEIVGTTSLSSALGVVYFLHAVPYLVSPPIAGWLVDTTGSYTAAFLLCGFAMIFSSILLGFVRIVKRMKRTQVPFPVKDSDPKLQLWTNGSVAYSVARELDQKDEEPLPKARSGCNLT", "length": 486 }, "evidence": [ { "id": "MGI:2147716", "url": "https://alliancegenome.org/gene/MGI:2147716#orthology", "database": "AGR" }, { "id": "HGNC:23094", "url": "https://alliancegenome.org/gene/HGNC:23094#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050522-80", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-80#orthology", "database": "AGR" }, { "id": "FB:FBgn0023549", "url": "https://alliancegenome.org/gene/FB:FBgn0023549#orthology", "database": "AGR" }, { "id": "RGD:1311468", "url": "https://alliancegenome.org/gene/RGD:1311468#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CE94-1", "protein_name": "Monocarboxylate transporter 13", "gene_name": "Slc16a13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVRRAEPPDGGWGWMVVLSAFFQSALVFGVLRSFGVFFVEFVAAFEEQAARVSWIASIGIAVQQFGSPIGSALSTKLGPRPVVMTGGILAALGMLLASFATSLTHLYLSIGLLSGSGWALTFTPTMACLSRYFSQRRSLAMGLALTGVGISSFAFAPLFQWLINNYAWRGALLLVSALSLHLMACGALLRPLSLTEDAAVGGPGAQITSLLRHGPFLRYTAALTLINTGFFIPYVHLVAHLQDLGWDPLPAAFLLSVAAVSDLVGRVASGWLGDAVPGPVARLLMLWTTLTGVSLALFPVAQASSTLVVLAVAYGFTSGALTPVAFSVLPELVGTGRIYCGMGLVQMIESIGGLLGAPLSGYLRDVTGNYTASFVVAGAFLLAGSGVLLTLPHFFSCISVSTSRPQDLVIEASDTKIPLPKEEGLGEN", "length": 428 }, "evidence": [ { "id": "HGNC:31037", "url": "https://alliancegenome.org/gene/HGNC:31037#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8K1C7-1", "protein_name": "Monocarboxylate transporter 14", "gene_name": "Slc16a14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MYTSHEDIGYDLEDDRKAKNKKTLKPHPDIDGGWAWMMVLSSFFVHILIMGSQMALGVLNVEWLEEFHQSRGLTAWVSSLSMGITLIVGPFIGLFINTCGCRQTAIIGGLVNSLGWVLSAYAANVQSLFITFGVAAGLGSGMAYLPAVVMVGRYFQKRRALAQGLSTTGTGFGTFLMTVLLKYLCAEYGWRNAMFIQGALSLNLCVCGALMRPLSPEKLENCPEAEEPCALPAYSTESVKSGGPLGMAEEQDRRPGNEEMVCDLQTQECQGQTHPRKNVCAFRVLKTVSQLTVQVRRGFRDWHSGYFGTASLFTNRMFVAFIFWALFAYSSFVIPFIHLPEIVSLYNLSEQNDTFPLTSIIAILHIFGKVILGAVADLPCISVWNVFLIANFTLVLSIFLLPLMHTYASLAVICALIGFSSGYFSLMPVVTEDLVGTEHLANAYGIIICANGISALLGPPFAGWIFDITQKYDFSFYICGLLYMVGILFLLIQPCIQMIDQSRRKCIEGAHV", "length": 512 }, "evidence": [ { "id": "MGI:1919031", "url": "https://alliancegenome.org/gene/MGI:1919031#orthology", "database": "AGR" }, { "id": "FB:FBgn0023549", "url": "https://alliancegenome.org/gene/FB:FBgn0023549#orthology", "database": "AGR" }, { "id": "HGNC:26417", "url": "https://alliancegenome.org/gene/HGNC:26417#orthology", "database": "AGR" }, { "id": "RGD:1309675", "url": "https://alliancegenome.org/gene/RGD:1309675#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8K1P8-1", "protein_name": "Monocarboxylate transporter 8", "gene_name": "SLC16A2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALPSPASEEAEGPCQEANQEYQEPVCSPVPEPEPEPEPEPEPEPEPVPVPPPEPQPEPEPQPLPDPAPLPVLGFEAEPVQEPEPTPTVETRGTARGFQPPEGGFGWIVVFAATWCNGSIFGIHNSVGILYSMLLEEEKEKNRQVEFQAAWVGALAMGMIFFCSPIVSIFTDRLGCRITATTGAAVAFIGLHTSSFTSSLSLRYFTYGILFGCGCSFAFQPSLVILGHYFQRRLGLANGVVSAGSSIFSMSFPFLIKMLGDRIKLAQTFQVLSTFMFVLTLLSLTYRPLLPSSQDTPSKRGAHTLRQRFLVQFRKYFNMRVFRQRTYRIWAFGIAAAALGYFVPYVHLMKYVEDKFKEIKETWVLLVCIGATSGLGRLVSGHISDSIPGLKKIYLQVLSFLLLGLMSMMIPLCRDFGGLIVVCLFLGLCDGFFITIMAPIAFELVGPMQASQAIGYLLGMMALPMIAGPPIAGLLRNCFGNYHVAFYFAGVPPIIGAVILFFVPLMHQRMFKKEQRESSKDKMLSHDPDPNGELLPGSPTPEEPI", "length": 545 }, "evidence": [ { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8NCK7-1", "protein_name": "Monocarboxylate transporter 11", "gene_name": "SLC16A11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTPQPAGPPDGGWGWVVAAAAFAINGLSYGLLRSLGLAFPDLAEHFDRSAQDTAWISALALAVQQAASPVGSALSTRWGARPVVMVGGVLASLGFVFSAFASDLLHLYLGLGLLAGFGWALVFAPALGTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQLLLDTFGWRGALLLLGAITLHLTPCGALLLPLVLPGDPPAPPRSPLAALGLSLFTRRAFSIFALGTALVGGGYFVPYVHLAPHALDRGLGGYGAALVVAVAAMGDAGARLVCGWLADQGWVPLPRLLAVFGALTGLGLWVVGLVPVVGGEESWGGPLLAAAVAYGLSAGSYAPLVFGVLPGLVGVGGVVQATGLVMMLMSLGGLLGPPLSGFLRDETGDFTASFLLSGSLILSGSFIYIGLPRALPSCGPASPPATPPPETGELLPAPQAVLLSPGGPGSTLDTTC", "length": 447 }, "evidence": [ { "id": "MGI:2663709", "url": "https://alliancegenome.org/gene/MGI:2663709#orthology", "database": "AGR" }, { "id": "HGNC:23093", "url": "https://alliancegenome.org/gene/HGNC:23093#orthology", "database": "AGR" }, { "id": "FB:FBgn0023549", "url": "https://alliancegenome.org/gene/FB:FBgn0023549#orthology", "database": "AGR" }, { "id": "RGD:1311125", "url": "https://alliancegenome.org/gene/RGD:1311125#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R0M8-1", "protein_name": "Probable monocarboxylate transporter 5", "gene_name": "Slc16a4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVKKEKTPSPYTKPLDGGWGWMVVLHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIGWIGSIMSSLRFSAGPLAAIICDVLGEKATSILGTFLVSGGYVISSWATGIPFLCVTMGLLPGLGSAFLYQVAAVVITKYFKKRLGLSTAIARSGMGLTFLLAPFTKFLIDLYDWTGALILFGAIILNLVPSSMLLRPIHSQSNNNSDIENKGSILSATEPEASYKTETSKCKETQEPFIKDSTMKKSEQPTTTLTVLGNQSEEFSNRPHRNRPLLMSNGKSHKKKFVSWNCKQKLLDISLFRNPFFYIFTWSFLLSQLAYFIPTFHLVARAKTLGIDVMDASYLVSVAGITETVSQLISGWIADQNWIKKYQYHKSYLILCGVTNLLAPLATTFPLLMAYTILFAIFAGGYLALILPVLVDLSKNSRVHKFLGYASFFAGIAVLSGPPIAGWIYDYTQTYTGSFYFSGTCYILSSVSLFFVPLAERWKRKQSDLLRTTIK", "length": 500 }, "evidence": [ { "id": "MGI:2385183", "url": "https://alliancegenome.org/gene/MGI:2385183#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070112-602", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070112-602#orthology", "database": "AGR" }, { "id": "FB:FBgn0023549", "url": "https://alliancegenome.org/gene/FB:FBgn0023549#orthology", "database": "AGR" }, { "id": "HGNC:10925", "url": "https://alliancegenome.org/gene/HGNC:10925#orthology", "database": "AGR" }, { "id": "RGD:1359655", "url": "https://alliancegenome.org/gene/RGD:1359655#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TF71-1", "protein_name": "Monocarboxylate transporter 10", "gene_name": "SLC16A10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVLSQEEPDSARGTSEAQPLGPAPTGAAPPPGPGPSDSPEAAVEKVEVELAGPATAEPHEPPEPPEGGWGWLVMLAAMWCNGSVFGIQNACGVLFVSMLETFGSKDDDKMVFKTAWVGSLSMGMIFFCCPIVSVFTDLFGCRKTAVVGAAVGFVGLMSSSFVSSIEPLYLTYGIIFACGCSFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLRVLIDSVGLFYTLRVLCIFMFVLFLAGFTYRPLATSTKDKESGGSGSSLFSRKKFSPPKKIFNFAIFKVTAYAVWAVGIPLALFGYFVPYVHLMKHVNERFQDEKNKEVVLMCIGVTSGVGRLLFGRIADYVPGVKKVYLQVLSFFFIGLMSMMIPLCSIFGALIAVCLIMGLFDGCFISIMAPIAFELVGAQDVSQAIGFLLGFMSIPMTVGPPIAGLLRDKLGSYDVAFYLAGVPPLIGGAVLCFIPWIHSKKQREISKTTGKEKMEKMLENQNSLLSSSSGMFKKESDSII", "length": 515 }, "evidence": [ { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q91Y77-1", "protein_name": "Monocarboxylate transporter 10", "gene_name": "Slc16a10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVPSQEEPAAAERETNEAQPPGPAPSDDAPLPVPGPSDVSDGSVEKVEVELTRSTGNQEPPEPPEGGWGWLVMLAAMWCNGSVFGIQNAYGVLFVSMLETFGAKDDDNMAFKAAWVGSLSMGMIFFCCPIVSVFTDMFGCRRTAVLGAAVGFVGLMSSSFVSSIEPLYFTYGVVFACGCSFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLGNLTSTVGLCYTLRILCIFMFVLFLAGFTYRPLVPSSKEKESEDSRSSFFSRRKLSPPKKIFNFALFKETAYAVWAAGIPLALFGYFVPYVHLMNHVKERFKDVNNKEVLFMCIGVTSGVGRLLFGRIADYLPGVKKVYLQVLSFFFIGLTSMMIPLCSVFGALIALCLIMGLFDGCFISIMAPIAFELVGPQDASQAIGFLLGFMSIPMTVGPPVAGLLHDKLGSYDLAFYLAGIPPFIGGAVLCLIPWIHSKKQREISKNTGGEKMEKMLANQSSLLSSSSGIFKKESDSII", "length": 514 }, "evidence": [ { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9V3F9-1", "protein_name": "Outsiders, isoform A", "gene_name": "out", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEKSSLTEKNHTQVYNDTTKPKKPKRRDKSDLGPDFVAPDGGWGWVVCLAAGLNNFFLFPALQQYGLIYRVRMQSLGFDAKQTTTIVNVVMAISSLVGIVNGAMFRRFTFRQVALTGTSLAFLGVFLSAFCTTFWQYIICLSAIFGIGLGLAMAATSLAVNTYFKLKRRRATGFSWTITGLGPIFFPQVSTVLLGYYGAQGTILIYAGIAMNAILCALTLQPVLWHVKKPEKPVHNTIEGIAETEKLQPELLEANGNLLSPSNDPWKDYECKYCQYQKRSKRGLFSSQYLFNVDDPERPGYEITEPGTPMLARANDGWFGSKLSLTSESAGGARSRTRQALMRQVSSRSRENLDRLEQNRHDQGPDTPSAAALYKPNYFNREREDLDRYASKTSVYSRPGQDELLRCTCAEDKALLQKTAESLQVNLFNNSADNTEAEEEAKRRMTFFQKVSKFFDLDLLRDFTFVNLAVGMSIMMFGEMNFSVLTPFILNSFGYTDTQISLVMSLLACMDISVRFLAPLALEKVKLDNRVLFAFGILCIAVGRVVVAFTDSYEIMIGVFLLIGFGKAFRTIFSPLIIPSYVPLNRLPAASGLQLIFNTIFSFAMGPILGILTEAYGYAATIHTINALTLLALLLWLAESVVRRILGIPSKGLGQ", "length": 655 }, "evidence": [ { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VQU7-1", "protein_name": "Major facilitator superfamily (MFS) profile domain-containing protein", "gene_name": "GH25970", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVIQCTCDCNCSDSRDNRSVISCLLPGRSQPYKLGSSFGGDDMEQRIPYYRRLSNTSSALYGSCPQLLPSSSSTNNRHSWLRIPKNPQENPSENPSENPRQYSSLVRPKQRSPVLCNKCALXRRYNLSCEHPKQTAGHPGSGNTDQTAQTKPDKDSTNQRYLCYECRFNNQPLAWWVSCPRLSYLPAEQTKMQSTTTPTRHCHGGVGTQTTLPQTTSTPPTLPRFPSKRHCDNFGSYATLPTIEHQMTMPMMPHCSRHGGGGGGGVVGVGGLGGAVGSGMPSVMPAPPPPRYANPNINGCCYMYNPMPPAHQSHHQHDHHHAQQHHPVAQHQHHPHQYGPQYCLCDNWYHQPPPTQQQQHHHQQRAKNLMANGGCYFGYEANHHPSLHATTPHPSHITDEEDSAFPGLADREFHLLHRNIPALRRTGVDTTRIRQYFYPDGGWGWIICGVSFLVHILTTGLQLSYGLLWFYAVQYLHNTSGIELLGALSWSVSMVATSFVVSLCRKRSIRLLSIVGGLVMPLGILFTSFATEFGQVVFSYGIVFGVGVAMVREASTVMLGNYFKRRRQFVEMVAMSGEGVGIALFSVILKEGVGKAGWRLGLQIVAALTALSFFMGLMYRPASLYHPQRRAIQHLKNQRKKMREKKPILSQDVESTPKYFFLDISSLKSVTVKILLMTSSVASFGIYTPMFLMALNAAEQGSDVQELVLLQTFLGISMALGVVIAGALLRRCFVIRHFVINTKIVTQLFLSIVALAILFLSFVMGYTGLCILSWLYGIGLGGFQYSLKILALERIKLKHFSKAWGFIRGVESVPVLISVPLTSFLNDYSLKYGRAGYYICSAAAAISGIIIFFISEPQQQHQQQQQQLHHHYQQRNGHLATPTLMRHASARQHRPHLPMDYGYGEYPAPDLLSRSCISLNQMEPYLQANFCQRHMLQQQQQQQQQQQHSHLQQLACHNLDLQPHQGREAYQLGQGSIGAKMGKRLQRSLSFIQQHSNCCDGQMYCSWHSTYELGCHKSNKNPGSADRQPLICTCSSPNRNPVTYGTHGPTGPPGPTGPPGPPSSTRSRSVPEGLSTMSQQCNCRQGPATFAAPTREFIYVPHAYASLQRTPHRHSQGAGSGPGPGNSALRNNPQCRLKRSQSLCRPNAVQFVEQITTSV", "length": 1159 }, "evidence": [ { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VWJ0-1", "protein_name": "Major facilitator superfamily (MFS) profile domain-containing protein", "gene_name": "Yqy", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTDNGNNHNNNNNNNNDEALRLRLPEEQAEQLLPKNGSAGQTKIAPPTHTHSIAAASVPQKVPAKKKRDKSDLGEDFVAPDGGWGWLVSVASGVNILVTFALAQQFGILFRDRMAGLGISSSELTTIINTQIAVSAFTGLLNGPLFRRYTYRVVALVGSVLTFLGLFWMVFADTFAVYIMSFSILYGFGRGLTVSASSLAVNTYFKVKRRTATAFQFGVAGLGPIVCPYFATYMLYEFGVQGTTLLFAGASLHTIACSLIYQPVKWHVVKRDRDAEALQQVQPLAEREDQDEDIIKNVVEPETPVLPRANDGWFGSRASLNSVGTRNRLNTWEKSDSNGHVELKRLSSKDSNPGRQLRSISVSHSIKEEEATGYNSDHEVQHTELTEKEKQELEDEKERQRRKKLPFYMKVVIFFDMDLLRDITYVNLAVGITLINFVEINFAILTPFILSDLGFNKDQIALAMSTLGFFDLVVRFLIPLITAKINLSNRTFFVVGILGMCIGRMFLSMTSNFYVMMAIFLWLGLNKAFRTVFWSLIIPSYVPLKRLPAAAGLQLLMSGTFSMIFGPLIGLIRDHTSYAVTLNLLNALCVMAFAGWYLEDFIRARSRKSPPVKSIN", "length": 616 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-131120-181", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131120-181#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VWJ1-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG8034", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MASKQPRKVAPDGGWGWVACFGVSLVNLATRSIEPSFGLLFGDTLKELNVGTTGAAVIISALDVCMNFSGLFVGPLLKEFSYRKVAIAGSLLCGLGLALTSPATSMAHILSTYSVINGIGVGLSTSAAFVALNHYFKHKRGQAVGLSMAGTAMGMLIMPQLVRILLEAYDFRGAVLLLAGVALNATVGSVLLQPVKWHMKEEFDDEELMCISALPTPQPQLTVGGAGGAASAGAPVFKVIKEDGNEEDALPEMNTLLFHKPHPHQHSMRKNYSEMAMNTMNGSRLGIPKRPTFPRIMSLAGVQSAAHGAGGDSGGYTSQAEVNATQLRCRKASVTSNLSYMDFTGSILQVHLNTGDDEFEQNDRELRRVGTATGSIVLGGHRDSFIKMKPTELDKQAEAAAALDEEAKKKAKKPGFWRRFADLLDIDMLKDKMFLNLLFGLSIFYVAEMNFKMVTPFFFANLGYQKTDVAFCLSITAITDIAARIVLPPIFDRTTIKKRTIFLVSIIFVALTRSIMAEQTEWTQLMIWLSICGFFRGSALSNFTLTVSEYCSLEKLPSAFGWHLVGKALFVITFGPLIGLIRDVTDSYPICIHTQSVCIMICATAWGIEYLVEYIQSRRRTADAAQLPTQDVGATTTATSDQNDVKL", "length": 647 }, "evidence": [ { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VWK0-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG14196", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEKKVYQDTTRPLPRVSRARYYNKHDKSDLGDDFVAPDAGWAWIVCVAAGVSNLSIYPCLQQFGFLFRERLSDLGMSSSQITAIINANPAVSACTGLLNGPMFRRFTFRQVAMAGSLLISGSLILTAFCETFLSYMVAYALLFGFGMGISVSASSLAINTYFQKKRRRAAGFSWTITGLGPIFLPHLVTFLLTIYGVQGTTLLFAAISLHSFVCALIYQPVRYHVKPPVEQLADQEQQAEALCAHCSWQQKREPGGIFSSQYLCQDDDAQRPGYEICEPGTPMLSRANDGWYGSRLSLTSGRLRFRTISSSKDLEQTQRLHCPISEEQNHESDEFLRPNNFRRERVESNLEAKLCCQCSAKREEHNNNRKEKEAEAEEAGMESAPLHDPQMSFLAKVVTFFDLDLLRDFTFVNLVAGLTIINFGELNFSILTPFILVDFGFDTPQITLAMSLLAGLDITMRFMVPFLTEKIPWDNRVFFLIGVVGIALGRTVVACTRSYSLILCSFVWIGLCKGVRTIFWPLIIPGYVPLNRLPGASGLQLLISGLFTLIGGPFVGLVRDRYDYSVTLHCLNMMSFVAATSWSLEALIRRHRRKQRLVNS", "length": 600 }, "evidence": [ { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W0L6-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG13907", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVDTNSSNPGIVGGNSASSARLRRFERTDSELACEEAARLTAEQSPEDEDNQDNDEDDDDEESVYGELPPPPDGGYGWVICFASFMCNMIVDGIAYTFGIFLEEFVAYFHEGKGTVAWVGSLLSGVYLSAGPIVSALANKYGCRAVCIAGSIIACIAFVLSTFSTNVSMLMATYGFMGGFGFGMIYLPAVVAVGYYFETKRSLATGIAVCGSGFGTFAFAPLATYLLEEYGWKNALLIFAGLILNCAIFGAMMRPLTYPKKKKQKPLMQRMYEEKQLQLERGSFAGSHFMVQLPDGTIERKLKMPLNADPGVHSSLNLELLAQQAGGGGLHPVSTLPTITESKVVDVHRQNGAQSPPNGDSNGQLSARSAAGAVGRRPHRNSESENSPYHSQDAMTRNASQPAFLAGDHQSLPKNGSVPAFNTRVRKTSASERFQPSLAAIRATSRGDLEAGAGGDFASSKLSLSQRQGGSQTGSSGRMVRPMSRKDIFYSGSVTNLPQYQSQKSLANYRNSVLSLTKYEKSMQSVAKLDPLAEAEKHREEYDLCPCLGIPDSVKSVVNTMLDVSLLKDPVFMLIGVSNIFGMAGLYVPFVYLVDAAKEHDIPKNDAAMLLSIIGITNTVGRVFCGWVADLPQVNSLLLNNCCLLVSTIAVTLTPLCYSYAAYITMSIFFGLAISGYISLTSIILVDLLGLDKLTNAFGLLILFRGFAALIGTPLAGAIYDMTHTYDLPFYMAGALFGISTITSFLAPCLKRCSPSEETPVHVETLTPIDEEQGEDAEDDEDQPITIVPKIIKTLASPQQEEGHPQFPQKTSESKL", "length": 816 }, "evidence": [ { "id": "MGI:1330284", "url": "https://alliancegenome.org/gene/MGI:1330284#orthology", "database": "AGR" }, { "id": "MGI:2443515", "url": "https://alliancegenome.org/gene/MGI:2443515#orthology", "database": "AGR" }, { "id": "MGI:2147716", "url": "https://alliancegenome.org/gene/MGI:2147716#orthology", "database": "AGR" }, { "id": "MGI:1929519", "url": "https://alliancegenome.org/gene/MGI:1929519#orthology", "database": "AGR" }, { "id": "MGI:2385183", "url": "https://alliancegenome.org/gene/MGI:2385183#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070112-602", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070112-602#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131120-181", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131120-181#orthology", "database": "AGR" }, { "id": "RGD:620603", "url": "https://alliancegenome.org/gene/RGD:620603#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121108-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121108-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121128-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121128-1#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-051113-248", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-051113-248#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110408-16", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110408-16#orthology", "database": "AGR" }, { "id": "HGNC:31037", "url": "https://alliancegenome.org/gene/HGNC:31037#orthology", "database": "AGR" }, { "id": "HGNC:26417", "url": "https://alliancegenome.org/gene/HGNC:26417#orthology", "database": "AGR" }, { "id": "HGNC:10924", "url": "https://alliancegenome.org/gene/HGNC:10924#orthology", "database": "AGR" }, { "id": "HGNC:10925", "url": "https://alliancegenome.org/gene/HGNC:10925#orthology", "database": "AGR" }, { "id": "RGD:1359655", "url": "https://alliancegenome.org/gene/RGD:1359655#orthology", "database": "AGR" }, { "id": "SGD:S000005479", "url": "https://alliancegenome.org/gene/SGD:S000005479#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005833", "url": "https://alliancegenome.org/gene/SGD:S000005833#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q9W509", "url": "https://www.uniprot.org/uniprotkb/Q9W509" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "monocarboxylic acid transmembrane transporter activity", "id": "GO:0008028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008028", "evidence": [ { "database": "UniProtKB", "id": "Q9W509", "url": "https://www.uniprot.org/uniprotkb/Q9W509" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "monocarboxylic acid transport", "id": "GO:0015718", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015718", "evidence": [ { "database": "UniProtKB", "id": "Q9W509", "url": "https://www.uniprot.org/uniprotkb/Q9W509" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 241, "end_pos": 243, "annotation": "n_glycosylation_sequon" }, { "start_pos": 290, "end_pos": 292, "annotation": "n_glycosylation_sequon" }, { "start_pos": 390, "end_pos": 392, "annotation": "n_glycosylation_sequon" }, { "start_pos": 419, "end_pos": 421, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9W509", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W509" }, { "id": "PS50850", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50850" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Major facilitator superfamily (MFS) profile", "eco_id": "ECO_0000259", "start_pos": 427, "end_pos": 626, "start_aa": "Val", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 104 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 241, "end_pos": 243 }, { "start_pos": 290, "end_pos": 292 }, { "start_pos": 390, "end_pos": 392 }, { "start_pos": 419, "end_pos": 421 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { 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"MAQFEKEIVQAVLIADNNVWNFKPLSDEGSTALLPLVNVRMLDYALMALNRSGVEEVFVYTSLYRSSIREHIRAGIATDAAWSFKMTVHVIGGEGCRCFGDAMRDLDNKALIRGHFILLGADTVTNADLRPVLEQHKRQAKFDKGTAATLVFKECANNVRTGNEVLIAVDRRNDRLHYHQRLRMHHKENRYQLPLDVFLGNSCVALHHNLLDPQIAIGSPSMLSLFNDNFDFQTRDDFVRGLLINEELLDSRIYVALLPAAQYAHKVNNWPAYQLVSRDIINRWAYPFVPDIGLYKLQQEYVFHKDNIYKSPEAHVSKVALLQNVVIEAGSHVDSGSVISDSVIGANCRIGKNCRLTNAFLMADVTVMDNCRLEHCVVGEGAIINEDCDVSAGCVLGAKSVLPAKKTLAKTLITRTPSRRRSDDEVVVELKSIGPHAYIVSDLTTGDPEDSECEDLLPQQPLSIPKMGDLLAPLDEISYCSDFSEDDEDASRAVTPLPDDTNIFLGEVIDSLTRGFREKSNPDFLVLEINSSRYAYNMSLKEVNFNVVKAVFGMQSIVEPANDNVLVAINAAFKQLGPVVSNYIKSEDSMMDCLKALEDVYEENHLVRGKISQIVHYLYDKDFVSESAIQAWYAQLDEEEHAHLRQSLAKLVAWLDQSSEEDDDEEDDD", "length": 669, "header": "tr|Q9W541-1|Q9W541_DROME Isoform 1 of Translation initiation factor eIF2B subunit epsilon OS=Drosophila melanogaster OX=7227 GN=eIF2Bepsilon PE=1 SV=1 CANONICAL=Q9W541-1" }, "isoforms": [ { "isoform_ac": "Q9W541-1", "url": "https://www.uniprot.org/uniprotkb/Q9W541/entry#Q9W541-1", "sequence": { "sequence": "MAQFEKEIVQAVLIADNNVWNFKPLSDEGSTALLPLVNVRMLDYALMALNRSGVEEVFVYTSLYRSSIREHIRAGIATDAAWSFKMTVHVIGGEGCRCFGDAMRDLDNKALIRGHFILLGADTVTNADLRPVLEQHKRQAKFDKGTAATLVFKECANNVRTGNEVLIAVDRRNDRLHYHQRLRMHHKENRYQLPLDVFLGNSCVALHHNLLDPQIAIGSPSMLSLFNDNFDFQTRDDFVRGLLINEELLDSRIYVALLPAAQYAHKVNNWPAYQLVSRDIINRWAYPFVPDIGLYKLQQEYVFHKDNIYKSPEAHVSKVALLQNVVIEAGSHVDSGSVISDSVIGANCRIGKNCRLTNAFLMADVTVMDNCRLEHCVVGEGAIINEDCDVSAGCVLGAKSVLPAKKTLAKTLITRTPSRRRSDDEVVVELKSIGPHAYIVSDLTTGDPEDSECEDLLPQQPLSIPKMGDLLAPLDEISYCSDFSEDDEDASRAVTPLPDDTNIFLGEVIDSLTRGFREKSNPDFLVLEINSSRYAYNMSLKEVNFNVVKAVFGMQSIVEPANDNVLVAINAAFKQLGPVVSNYIKSEDSMMDCLKALEDVYEENHLVRGKISQIVHYLYDKDFVSESAIQAWYAQLDEEEHAHLRQSLAKLVAWLDQSSEEDDDEEDDD", "length": 669, "header": "tr|Q9W541-1|Q9W541_DROME Isoform 1 of Translation initiation factor eIF2B subunit epsilon OS=Drosophila melanogaster OX=7227 GN=eIF2Bepsilon PE=1 SV=1 CANONICAL=Q9W541-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W541", "url": "https://www.uniprot.org/uniprotkb/Q9W541" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W541", "url": "https://www.uniprot.org/uniprotkb/Q9W541" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W541", "url": "https://www.uniprot.org/uniprotkb/Q9W541" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W541", "url": "https://www.uniprot.org/uniprotkb/Q9W541" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W541", "url": "https://www.uniprot.org/uniprotkb/Q9W541" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W541", "url": "https://www.uniprot.org/uniprotkb/Q9W541" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W541", "url": "https://www.uniprot.org/uniprotkb/Q9W541" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W541", "url": "https://www.uniprot.org/uniprotkb/Q9W541" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W541", "url": "https://www.uniprot.org/uniprotkb/Q9W541" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W541", "url": "https://www.uniprot.org/uniprotkb/Q9W541" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W541", "url": "https://www.uniprot.org/uniprotkb/Q9W541" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG3806", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG3806", "resource": "KEGG Pathway" }, { "id": "R-DME-72731", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-72731", "resource": "Reactome", "description": "Recycling of eIF2:GDP" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZAC8-1", "protein_name": "Translation initiation factor eIF2B subunit epsilon", "gene_name": "EIF2B5", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MATSTSSSTERIPGCQQRSRRMLRVEEAQQFIWQKPASEKQRRGDKRAKNKAKPALLPMANVAMIDYTLEFLTATGVEETFVFCCWKSAEIKEHLQKSKWCRHTSPNTVRFVTSDLYRSLGDVLRDVDAKSLVRSDFILVTGDVVSNLNISRALEEHKLRRKMEKNVSVMTMIFKESSPGHHARCKEDDIVIAMDSATNRVLHYQRTQGLKRFRFPMSLFQNTIENVEVRHDLLDCHISICSPQVAELFTDNFDYQTRDDFVRGLLVNEEILGNQIHMHVTTEEYGAHICNLLMYEAVCSDIIRRWVYPLTPEMNFTDDKNQNYTHSKHNIYRGVDVSLGHGSMLKENVLIGQGTVIGSNCSIMNSVIGQNCRIGDEVTLDGAFLWDGVHVADNVQIHHSVICDEAEVKEKVKLKPHCVLSSQVVVGPDITLSEGTVISLHPPDEEEEDDDQFSDDSGVNKEESKVKLKGYNKKDVGSEGRGYLWKADDKNEDDEEQRQSLWGPAMLSEEESESDSDLSMGSEEPDSRAASPQLDDIKVFQNEVLGTLQRGEEENISCDNLVLEINSLKYAYNISLNEMMQVLSKVILEFPLQQLDANLDSQNYFSALLPLLKNWTPLFKNYIKRSSDHLNALFAIEEFFLEHDSLCTSIAKVLMTFYQLEILEEDVILNWFSLRDTSDKGKQLRKNQRLQKFIQWLEEAEEESSDGDQD", "length": 710 }, "evidence": [ { "id": "Q9W541", "url": "https://omabrowser.org/oma/group/Q9W541/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E1BPB3-1", "protein_name": "Translation initiation factor eIF2B subunit epsilon", "gene_name": "EIF2B5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAATVVAPPGALASRVNKRSGGGPGGGGGGGGGGGGGAARGAEEEPPPPLQAVLVADSFNRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIKEHLLKSKWCRPTSLNVVRIITSELYRSLGDVLRDVDAKALVRSDFLLVYGDVISNINITRALEEHRLRRKLEKNVSVMTMIFKESSPSHPTRCHEDNVVVAVDSATNQVLHFQKTQGLRRFSFPLSLFQGSGDGVEIRYDLLDCHISICSPQVAQLFTDNFDYQTRDDFVRGLLVNEEILGNQIHMHVTTKEYGARVSNLHMYAAVCADVIRRWVYPLTPEANFTDSTTQSCTHSRHNIYRGPEVSLGHGSILEENVLLGSGTVIGSNCSITNSVIGPGCHIGDNVVLDQAFLWQGVRVAAGAQIHQSLLCDNAEVKENVTLKPHCVLTSQVVVGPDIMLPEGSVISLHPPDAEDDEDDGQFSDDSGADQEKEKMKLKGYNPAEVGVAGQGYLWKAADMNMEEEEELRQNLWGLKINMEEESETESERSMDSEELDSRAGSPQMDDIKVFQNEVLGTLQRGKEENISCDNLVLEINSLKYAYNISLKEVMQVLSHVVLEFPLQQMDSPLDPNRYCTLLIPLLKAWSPVFRNYIKRAADHLESLAAIEDFFLEHEALSTSMAKVLMAFYQLEILAEETILSWFSRREVTDKGQQLRKNQQLQRFIQWLKEAEEESSEDD", "length": 728 }, "evidence": [ { "id": "Q9W541", "url": "https://omabrowser.org/oma/group/Q9W541/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O64760-1", "protein_name": "Translation initiation factor eIF2B subunit epsilon", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGAQKKGGAAARVSEDAEVQSRHRLQAILLADSFATKFRPVTLERPKVLLPIVNVPMIDYTLAWLESAGIEEVFVFCCAHSMQVIEYLEKSEWYSHPNLLVRTIESHKSISAGDALRYMYEQQTETSQIQGDFVLVSGDTVSNMPLADLIQEHRERKKKDEKAIMTMVIKQSKSSPLTHQSRLGTDQLFIAVDPLTKQLLHYEEDKIDHPSGSVCLEKSLLDTNPSVLVCNDMQDCYIDICSPEVLSLFEDNFDYQHLRRHFVKGVLVDDIMGYKIFTHEIHSSYAGRIDNFRSYDTVSKDIIQRWTYPYVPDINFSGNRPLKLGRQGIYKASDVVQSRSADVGASTVIGYGTKIGHGDKIMNSVIGNGCSIGSNVVIEGSYIWNNVTIEDGCEIRNAIVCDGVKIRAGAVLQPGVVLSFNVVVGRDFVVPAYSKVSLLQQPTTEDSDEELEYADSSSGTADHLSGLNLQMESKASELGPDGAGYIWEVCEGAHDEEWKHSVAPIPKDKLSEITQAIDDDDTDDESVVPTSGELKSDADSINTDVNDPNDDYYYFEKEVEGTVLRAVEENIKVDLVTMEINGLRLSFNMESADCAGATFFSMIKLALDTPHNSGSELYKNAASIITKWKDLLGFYAKKIDEQIEVIMKFEEMCQESHKELGPLFTQILHLLYDKDVLQEDAILRWEEEKAGADEADKVYLKQCDTFIQWLKEASEEEDEDDEDEEEEEDN", "length": 730 }, "evidence": [ { "id": "Q9W541", "url": "https://omabrowser.org/oma/group/Q9W541/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P32501-1", "protein_name": "Translation initiation factor eIF2B subunit epsilon", "gene_name": "GCD6", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAGKKGQKKSGLGNHGKNSDMDVEDRLQAVVLTDSYETRFMPLTAVKPRCLLPLANVPLIEYTLEFLAKAGVHEVFLICSSHANQINDYIENSKWNLPWSPFKITTIMSPEARCTGDVMRDLDNRGIITGDFILVSGDVLTNIDFSKMLEFHKKMHLQDKDHISTMCLSKASTYPKTRTIEPAAFVLDKSTSRCIYYQDLPLPSSREKTSIQIDPELLDNVDEFVIRNDLIDCRIDICTSHVPLIFQENFDYQSLRTDFVKGVISSDILGKHIYAYLTDEYAVRVESWQTYDTISQDFLGRWCYPLVLDSNIQDDQTYSYESRHIYKEKDVVLAQSCKIGKCTAIGSGTKIGEGTKIENSVIGRNCQIGENIRIKNSFIWDDCIIGNNSIIDHSLIASNATLGSNVRLNDGCIIGFNVKIDDNMDLDRNTKISASPLKNAGSRMYDNESNEQFDQDLDDQTLAVSIVGDKGVGYIYESEVSDDEDSSTEACKEINTLSNQLDELYLSDDSISSATKKTKKRRTMSVNSIYTDREEIDSEFEDEDFEKEGIATVERAMENNHDLDTALLELNTLRMSMNVTYHEVRIATITALLRRVYHFIATQTLGPKDAVVKVFNQWGLLFKRQAFDEEEYIDLMNIIMEKIVEQSFDKPDLILFSALVSLYDNDIIEEDVIYKWWDNVSTDPRYDEVKKLTVKWVEWLQNADEESSSEEE", "length": 712 }, "evidence": [ { "id": "RGD:708380", "url": "https://alliancegenome.org/gene/RGD:708380#orthology", "database": "AGR" }, { "id": "MGI:2446176", "url": "https://alliancegenome.org/gene/MGI:2446176#orthology", "database": "AGR" }, { "id": "HGNC:3261", "url": "https://alliancegenome.org/gene/HGNC:3261#orthology", "database": "AGR" }, { "id": "FB:FBgn0023512", "url": "https://alliancegenome.org/gene/FB:FBgn0023512#orthology", "database": "AGR" }, { "id": "SGD:S000002619", "url": "https://alliancegenome.org/gene/SGD:S000002619#orthology", "database": "AGR" }, { "id": "Q9W541", "url": "https://omabrowser.org/oma/group/Q9W541/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q13144-1", "protein_name": "Translation initiation factor eIF2B subunit epsilon", "gene_name": "EIF2B5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAPVVAPPGVVVSRANKRSGAGPGGSGGGGARGAEEEPPPPLQAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIKEHLLKSKWCRPTSLNVVRIITSELYRSLGDVLRDVDAKALVRSDFLLVYGDVISNINITRALEEHRLRRKLEKNVSVMTMIFKESSPSHPTRCHEDNVVVAVDSTTNRVLHFQKTQGLRRFAFPLSLFQGSSDGVEVRYDLLDCHISICSPQVAQLFTDNFDYQTRDDFVRGLLVNEEILGNQIHMHVTAKEYGARVSNLHMYSAVCADVIRRWVYPLTPEANFTDSTTQSCTHSRHNIYRGPEVSLGHGSILEENVLLGSGTVIGSNCFITNSVIGPGCHIGDNVVLDQTYLWQGVRVAAGAQIHQSLLCDNAEVKERVTLKPRSVLTSQVVVGPNITLPEGSVISLHPPDAEEDEDDGEFSDDSGADQEKDKVKMKGYNPAEVGAAGKGYLWKAAGMNMEEEEELQQNLWGLKINMEEESESESEQSMDSEEPDSRGGSPQMDDIKVFQNEVLGTLQRGKEENISCDNLVLEINSLKYAYNISLKEVMQVLSHVVLEFPLQQMDSPLDSSRYCALLLPLLKAWSPVFRNYIKRAADHLEALAAIEDFFLEHEALGISMAKVLMAFYQLEILAEETILSWFSQRDTTDKGQQLRKNQQLQRFIQWLKEAEEESSEDD", "length": 721 }, "evidence": [ { "id": "RGD:708380", "url": "https://alliancegenome.org/gene/RGD:708380#orthology", "database": "AGR" }, { "id": "MGI:2446176", "url": "https://alliancegenome.org/gene/MGI:2446176#orthology", "database": "AGR" }, { "id": "HGNC:3261", "url": "https://alliancegenome.org/gene/HGNC:3261#orthology", "database": "AGR" }, { "id": "FB:FBgn0023512", "url": "https://alliancegenome.org/gene/FB:FBgn0023512#orthology", "database": "AGR" }, { "id": "SGD:S000002619", "url": "https://alliancegenome.org/gene/SGD:S000002619#orthology", "database": "AGR" }, { "id": "Q9W541", "url": "https://omabrowser.org/oma/group/Q9W541/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q64350-1", "protein_name": "Translation initiation factor eIF2B subunit epsilon", "gene_name": "Eif2b5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAATAAVPSAVGGRANKRGGGSGGGGTQGAEEEPPPPLQAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIKEHLQKSKWCHPTSLNVVRIITSDLYRSLGDVLRDVDAKALVRSDFLLIYGDVVSNINISKALEEHRLRRKLEKNVSVMTMVFKESSPSHPTRCHEDNVVLAVDSTTNRILHFQKTQGLRHFSFPLGLFQGSLDGVEIRYDLLDCHISICSPQVAQLFTDNFDYQTRDDFVRGLLVNEEILGNQIHLHVTSREYGARVSNLHMYSAVCADVIRRWVYPLTPEVNFTDSSTQSYTHSRHNIYRGPEVSLGHGSVLEENVLLGAGTVVGSNCSITNSVIGPNCHIGDNVVLDQAYLWQGVRVAAGAQIHQSLLCDRAEVKERVILKPHCVLTSQVVVGPDIILPEGSVISLHPPDAEEDEDDGQFSDDSGADQEKEKVKLKGYNPAEVGPEGQGYLWKAEDVDEKEDEELRQSLWGLMINMEEESETESERSVDPEELDSRAGSPQLDDIRVFQNEVLGTLQRGREENISCDNLVLEINSLKYAYNISLKEVMQVLSHVVLEFPLQQVDGVLDPNRYCALLLPLLKAWSPVFRNYIKRAADHLEALAAIEDFFLEHETLVPSLAKVLMAFYQLEILAEETILSWFSQRDITDKGQQLRKNQQLQRFIQWLREAEEESSDDD", "length": 716 }, "evidence": [ { "id": "RGD:708380", "url": "https://alliancegenome.org/gene/RGD:708380#orthology", "database": "AGR" }, { "id": "MGI:2446176", "url": "https://alliancegenome.org/gene/MGI:2446176#orthology", "database": "AGR" }, { "id": "HGNC:3261", "url": "https://alliancegenome.org/gene/HGNC:3261#orthology", "database": "AGR" }, { "id": "FB:FBgn0023512", "url": "https://alliancegenome.org/gene/FB:FBgn0023512#orthology", "database": "AGR" }, { "id": "SGD:S000002619", "url": "https://alliancegenome.org/gene/SGD:S000002619#orthology", "database": "AGR" }, { "id": "Q9W541", "url": "https://omabrowser.org/oma/group/Q9W541/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8CHW4-1", "protein_name": "Translation initiation factor eIF2B subunit epsilon", "gene_name": "Eif2b5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAATAAVPGAAAGRASKRGGGGSGGGGTQGAEEEPPPPLQAVLVADSFNRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIKEHLQKSKWCHPTSPNVVRIITSELYRSLGDVLRDVDAKALVRSDFLLIYGDVISNINICRALEEHRLRRKLEKNVSVMTMVFKESSPSHPTRCHEDNVVMAVDSATNRVLHFQKTQGLRRFSFPLSLFQGSGDGVEIRYDLLDCHISICSPQVAQLFTDNFDYQTRDDFVRGILMNEEVLGNQIHLHVTTREYGARVSNLHMYSAVCADVIRRWVYPLTPEVNFTDSTTQSYTHSRHNIYRGPEVSLGHGSVLEENVLLGAGTVIGSNCSITNSVIGPNCHIGDNVVLDQAYLWQGVRVAAGAQIHQSLLCDRAEVKERVKLKPYCVLTSQVVVGPDITLPEGSVISLHPPDAEEDEDDGQFSDDSGADQEKEKVKLKGYNPAEVGLEGQGYLWKAEGVNSKEDEELRQSLWGLMIKTEEESETESEGSVDPEELDSRAGSPQLDDIRVFQNEVLGTLQRGREENISCENLVLEINSLKHAYNISLKEVMQVLTLVVLEFPLQQVDGLLDPNRYCALLLPLLKAWSPVLRNYIKRAADHLEALAAIEDFFLEHETLVTSMAKVLMAFYQLEILAEETILSWFSQRDTTDEGQQLRKNQQLQRFIQWLREAEEESSEDD", "length": 717 }, "evidence": [ { "id": "RGD:708380", "url": "https://alliancegenome.org/gene/RGD:708380#orthology", "database": "AGR" }, { "id": "MGI:2446176", "url": "https://alliancegenome.org/gene/MGI:2446176#orthology", "database": "AGR" }, { "id": "HGNC:3261", "url": "https://alliancegenome.org/gene/HGNC:3261#orthology", "database": "AGR" }, { "id": "FB:FBgn0023512", "url": "https://alliancegenome.org/gene/FB:FBgn0023512#orthology", "database": "AGR" }, { "id": "SGD:S000002619", "url": "https://alliancegenome.org/gene/SGD:S000002619#orthology", "database": "AGR" }, { "id": "Q9W541", "url": "https://omabrowser.org/oma/group/Q9W541/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q9W541", "url": "https://www.uniprot.org/uniprotkb/Q9W541" } ], "pmid": "" }, { "name": "eukaryotic translation initiation factor 2B complex", "id": "GO:0005851", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005851", "evidence": [ { "database": "UniProtKB", "id": "Q9W541", "url": "https://www.uniprot.org/uniprotkb/Q9W541" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "Q9W541", "url": "https://www.uniprot.org/uniprotkb/Q9W541" } ], "pmid": "" }, { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "Q9W541", "url": "https://www.uniprot.org/uniprotkb/Q9W541" } ], "pmid": "" }, { "name": "nucleotidyltransferase activity", "id": "GO:0016779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016779", "evidence": [ { "database": "UniProtKB", "id": "Q9W541", "url": "https://www.uniprot.org/uniprotkb/Q9W541" } ], "pmid": "" }, { "name": "translation initiation factor binding", "id": "GO:0031369", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031369", "evidence": [ { "database": "UniProtKB", "id": "Q9W541", "url": "https://www.uniprot.org/uniprotkb/Q9W541" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "translational initiation", "id": "GO:0006413", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006413", "evidence": [ { "database": "UniProtKB", "id": "Q9W541", "url": "https://www.uniprot.org/uniprotkb/Q9W541" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 50, "end_pos": 52, "annotation": "n_glycosylation_sequon" }, { "start_pos": 530, "end_pos": 532, "annotation": "n_glycosylation_sequon" }, { "start_pos": 537, "end_pos": 539, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9W541", "database": 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protein 18 OS=Drosophila melanogaster OX=7227 GN=i207 PE=1 SV=1 CANONICAL=Q9W550-1" }, "isoforms": [ { "isoform_ac": "Q9W550-1", "url": "https://www.uniprot.org/uniprotkb/Q9W550/entry#Q9W550-1", "sequence": { "sequence": "MEDAVEALFISTSSEDNTTCSVQDLRTGTDLMRYKGGGCAQHHSLNMIHLNYVMAANSAKPLLHVWPINKQEQMAGLRFVVPGKVNALALTPDGNFLVAGIQENIYLWHMSSGRMLNTLSKHYQAITCLRFTDNGEHFISGGKDGAVLVWDLTFSAAPLDTGGGKDSTEPLYSFNDHGLAVTDLYSGIGGIRSYLYTVSLDRCCKVYDLCGGVLLLSVVFPVALHSVIVSKMETRVYVGSSDGKVFVFNMENAPRMKEYHLEGEEIQAFVGHTYGKAITCLALNISATTLVSGGEDNQVCVWDVGSRQLIKSLSQKGSVTNLHIRLLSPAIFLPEHKQPQMFADSLKRMISPWDENDCIELFDPDYSGGRKTPELDYTQSHPGTDEEIILKLIASMSSGKNEDDEGIEAETKATDVEDSEVEEEEPESEPMETASKEAESEKSYAEYQPDSAQTSDERVQELQAENARLKAQSMRLFQIAFKYITSDTNGQAEITEKTKRKKARKT", "length": 506, "header": "tr|Q9W550-1|Q9W550_DROME Isoform 1 of WD repeat-containing protein 18 OS=Drosophila melanogaster OX=7227 GN=i207 PE=1 SV=1 CANONICAL=Q9W550-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W550", "url": "https://www.uniprot.org/uniprotkb/Q9W550" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W550", "url": "https://www.uniprot.org/uniprotkb/Q9W550" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W550", "url": "https://www.uniprot.org/uniprotkb/Q9W550" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W550", "url": "https://www.uniprot.org/uniprotkb/Q9W550" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W550", "url": "https://www.uniprot.org/uniprotkb/Q9W550" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W550", "url": "https://www.uniprot.org/uniprotkb/Q9W550" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W550", "url": "https://www.uniprot.org/uniprotkb/Q9W550" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W550", "url": "https://www.uniprot.org/uniprotkb/Q9W550" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W550", "url": "https://www.uniprot.org/uniprotkb/Q9W550" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W550", "url": "https://www.uniprot.org/uniprotkb/Q9W550" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W550", "url": "https://www.uniprot.org/uniprotkb/Q9W550" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG14805", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG14805", "resource": "KEGG Pathway" }, { "id": "R-DME-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" } ], "orthologs": [ { "uniprot_canonical_ac": "P53877-1", "protein_name": "Pre-rRNA-processing protein IPI3", "gene_name": "IPI3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDEQVIFTTNTSGTIASVHSFEQINLRQCSTQSRNSCVQVGNKYLFIAQAQKALINVYNLSGSFKRESVEQRLPLPEILKCLEVVENDGVQYDRIQGVNHNLPDFNLPYLLLGSTESGKLYIWELNSGILLNVKPMAHYQSITKIKSILNGKYIITSGNDSRVIIWQTVDLVSASNDDPKPLCILHDHTLPVTDFQVSSSQGKFLSCTDTKLFTVSQDATIRCYDLSLIGSKKKQKANENDVSIGKTPVLLATFTTPYSIKSIVLDPADRACYIGTAEGCFSLNLFYKLKGNAIVNLLQSAGVNTVQKGRVFSLVQRNSLTGGENEDLDALYAMGQLVCENVLNSNVSCLEISMDGTLLLIGDTEGKVSIAEIYSKQIIRTIQTLTTSQDSVGEVTNLLTNPYRLERGNLLFEGESKGKQPSNNNGHNFMKIPNLQRVIFDGKNKGHLHDIWYQIGEPEAETDPNLALPLNDFNAYLEQVKTQESIFSHIGKVSSNVKVIDNKIDATSSLDSNAAKDEEITELKTNIEALTHAYKELRDMHEKLYEEHQQMLDKQ", "length": 555 }, "evidence": [ { "id": "RGD:1310646", "url": "https://alliancegenome.org/gene/RGD:1310646#orthology", "database": "AGR" }, { "id": "MGI:2158400", "url": "https://alliancegenome.org/gene/MGI:2158400#orthology", "database": "AGR" }, { "id": "HGNC:17956", "url": "https://alliancegenome.org/gene/HGNC:17956#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040905-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040905-4#orthology", "database": "AGR" }, { "id": "FB:FBgn0023514", "url": "https://alliancegenome.org/gene/FB:FBgn0023514#orthology", "database": "AGR" }, { "id": "SGD:S000005126", "url": "https://alliancegenome.org/gene/SGD:S000005126#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q499N3-1", "protein_name": "WD repeat-containing protein 18", "gene_name": "Wdr18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAPMEVVVCTDSAAPLWSCMVWELHSGANLLTYRGGQAGPRGLALLNGEYLLAAQQGKNYICAWELQRKDQLQQKIMCPGPVTCLTTAPNGLYVLAGIAESIYLWEVSTGNLLVILSRHYQDVSCLKFTGDGSHFVSAGKDCLVLAWSLCSVLQADPSRILAPRHVWSQHTLPITDLHCGFGGPMARVATASLDQTMKLWAISSGDLLLSVLFDMGITSVTMDLAEHYIFCGGSDGSIFQVDLCSRPGPREQSFQPEQNTGKVFKGHRNQVTCLSVSTDGSILLSGSHDESVRLWDVKSKQCVRTVPLKGPVTNAAITLAPPSMLNPEFRPSLPLPHFNKHLLGAEHGDEAQGGGLRLQLGLHLQGKEPSYLERLEQLQAALSGYLEKNMLGSQMLPVRVFELEEEVRSLRKINRDLFDFSTRIITRPSK", "length": 431 }, "evidence": [ { "id": "RGD:1310646", "url": "https://alliancegenome.org/gene/RGD:1310646#orthology", "database": "AGR" }, { "id": "MGI:2158400", "url": "https://alliancegenome.org/gene/MGI:2158400#orthology", "database": "AGR" }, { "id": "HGNC:17956", "url": "https://alliancegenome.org/gene/HGNC:17956#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040905-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040905-4#orthology", "database": "AGR" }, { "id": "FB:FBgn0023514", "url": "https://alliancegenome.org/gene/FB:FBgn0023514#orthology", "database": "AGR" }, { "id": "SGD:S000005126", "url": "https://alliancegenome.org/gene/SGD:S000005126#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4VBE8-1", "protein_name": "WD repeat-containing protein 18", "gene_name": "Wdr18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAPMEVVVCTDAAAQLWSCVVWELHSGANLLTYRGGQAGPRGLALLNGEYLLAAQQGKNYICAWELQRKDQLQQKIMCPGPVTCLTTAPNGLYVLAGIAESIYLWEVCTGNLLVILSRHYQDVSCLKFTGDGSHFVSAGKDCLALAWSLCSVLQADPSRILAPRHVWSQHTLPITDLHCGFGGPMARVATASLDQTVKLWAISSGDLLLSVLFDMGITSVTMDLAEHHIFCGGSDGSIFQVDLCSWPGLREHSFQPEQNTGKVFKGHRNQVTCLSVSTDGSVLLSGSHDESVRLWDVKSKQCLRTVTLKGPVTNAAIILAPPSMLNPEFRPSLPLPHFNKHLLGAEHGDEAQGGGLRLQLGLHLQGKEPSYLERLEQLQAVLSSYLEKNMLGSQMLPARVFDLEDEVRSLRKINRDLFDFSTRIITRPSK", "length": 431 }, "evidence": [ { "id": "RGD:1310646", "url": "https://alliancegenome.org/gene/RGD:1310646#orthology", "database": "AGR" }, { "id": "MGI:2158400", "url": "https://alliancegenome.org/gene/MGI:2158400#orthology", "database": "AGR" }, { "id": "HGNC:17956", "url": "https://alliancegenome.org/gene/HGNC:17956#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040905-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040905-4#orthology", "database": "AGR" }, { "id": "FB:FBgn0023514", "url": 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{ "id": "MGI:2158400", "url": "https://alliancegenome.org/gene/MGI:2158400#orthology", "database": "AGR" }, { "id": "HGNC:17956", "url": "https://alliancegenome.org/gene/HGNC:17956#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040905-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040905-4#orthology", "database": "AGR" }, { "id": "FB:FBgn0023514", "url": "https://alliancegenome.org/gene/FB:FBgn0023514#orthology", "database": "AGR" }, { "id": "SGD:S000005126", "url": "https://alliancegenome.org/gene/SGD:S000005126#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9BV38-1", "protein_name": "WD repeat-containing protein 18", "gene_name": "WDR18", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAPMEVAVCTDSAAPMWSCIVWELHSGANLLTYRGGQAGPRGLALLNGEYLLAAQLGKNYISAWELQRKDQLQQKIMCPGPVTCLTASPNGLYVLAGVAESIHLWEVSTGNLLVILSRHYQDVSCLQFTGDSSHFISGGKDCLVLVWSLCSVLQADPSRIPAPRHVWSHHALPITDLHCGFGGPLARVATSSLDQTVKLWEVSSGELLLSVLFDVSIMAVTMDLAEHHMFCGGSEGSIFQVDLFTWPGQRERSFHPEQDAGKVFKGHRNQVTCLSVSTDGSVLLSGSHDETVRLWDVQSKQCIRTVALKGPVTNAAILLAPVSMLSSDFRPSLPLPHFNKHLLGAEHGDEPRHGGLTLRLGLHQQGSEPSYLDRTEQLQAVLCSTMEKSVLGGQDQLRVRVTELEDEVRNLRKINRDLFDFSTRFITRPAK", "length": 432 }, "evidence": [ { "id": "RGD:1310646", "url": "https://alliancegenome.org/gene/RGD:1310646#orthology", "database": "AGR" }, { "id": "MGI:2158400", "url": "https://alliancegenome.org/gene/MGI:2158400#orthology", "database": "AGR" }, { "id": "HGNC:17956", "url": "https://alliancegenome.org/gene/HGNC:17956#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040905-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040905-4#orthology", "database": "AGR" }, { "id": "FB:FBgn0023514", "url": "https://alliancegenome.org/gene/FB:FBgn0023514#orthology", "database": "AGR" }, { "id": "SGD:S000005126", "url": "https://alliancegenome.org/gene/SGD:S000005126#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nuclear pre-replicative complex", "id": "GO:0005656", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005656", "evidence": [ { "database": "UniProtKB", "id": "Q9W550", "url": "https://www.uniprot.org/uniprotkb/Q9W550" } ], "pmid": "" }, { "name": "rixosome complex", "id": "GO:0120330", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120330", "evidence": [ { "database": "UniProtKB", "id": "Q9W550", "url": "https://www.uniprot.org/uniprotkb/Q9W550" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "Q9W550", "url": "https://www.uniprot.org/uniprotkb/Q9W550" } ], "pmid": "" }, { "name": "DNA-templated DNA replication", "id": "GO:0006261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006261", "evidence": [ { "database": "UniProtKB", "id": "Q9W550", "url": "https://www.uniprot.org/uniprotkb/Q9W550" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 17, "end_pos": 19, "annotation": "n_glycosylation_sequon" }, { "start_pos": 284, "end_pos": 286, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 17, "end_pos": 19 }, { "start_pos": 284, "end_pos": 286 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9W5A7-1", "uniprot_ac": "Q9W5A7", "uniprot_id": "Q9W5A7_DROME", "mass": { "chemical_mass": 49913.0, "monoisotopic_mass": 49913.0 }, "refseq": { "ac": "NP_569894", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_569894" }, "gene_names": [ { "name": "Dmel\\CG11381", "type": "recommended", "evidence": [ { "id": "Q9W5A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W5A7" } ] }, { "name": "CG11381", "type": "synonym", "evidence": [ { "id": "NP_569894", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_569894" }, { "id": "Q9W5A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W5A7" } ] }, { "name": "Dmel\\CG11381", "type": "synonym", "evidence": [ { "id": "NP_569894", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_569894" } ] }, { "name": "Dmel_CG11381", "type": "synonym", "evidence": [ { "id": "Q9W5A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W5A7" } ] } ], "protein_names": [ { "name": "CG11381-PA", "type": "synonym", "evidence": [ { "id": "NP_569894", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_569894" } ] }, { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "Q9W5A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W5A7/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_569894", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_569894" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W5A7", "url": "https://www.uniprot.org/uniprotkb/Q9W5A7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG11381", "url": "https://www.uniprot.org/uniprotkb/Q9W5A7", "locus": { "chromosome": "X", "start_pos": 1205433, "end_pos": 1203777, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0029568", "url": "https://www.ensemblgenomes.org/id/FBgn0029568" } ] } } ], "crossref": [ { "id": "FB:FBgn0029568", "url": "https://alliancegenome.org/gene/FB:FBgn0029568", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0029568", "url": "https://bgee.org/?page=gene&gene_id=FBgn0029568", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0029568", "url": "https://flybase.org/reports/FBgn0029568", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "31067", "url": "https://www.ncbi.nlm.nih.gov/gene/31067", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dme:Dmel_CG11381", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG11381", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "REFQPPY", "url": "https://omabrowser.org/oma/group/REFQPPY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W5A7", "url": "https://www.orthodb.org/?gene=Q9W5A7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "NP_569894", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_569894", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W5A7", "url": "https://www.uniprot.org/uniprotkb/Q9W5A7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W5A7-1", "url": "https://www.uniprot.org/uniprotkb/Q9W5A7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLKAAKIPLFFALLGAVCIQAVVVGPQPLHNNNRNGYRYNGPAHKYLPSEESHSHGSPLDSSHQHDQQGPSNAYNSHHYPAQEQHGQGAPEHDHQQKEVDSWQTALSQQQHESFGNQQNHQNAYNEGPVYQHYQGFNHQQHYGLSQQQQHESYGQEHYQQSPNQLQHHQSQHANEYAYEPAHFQQQQQHHEIQGHKQHQQRKEHWNFVQEQQPQNHEPWQSSHGFQQHQQQHSNRFESQLPLREDLWQPIRELDLEKLPSAEAHASSHKTVAAPGRDVKLVPSYTLSSDFEHDRFIGLDSTDTRLLTQSLPDAYRKQLFSSPPEPSSLAQGHNQQHKPGSAAYGGSHGPSLGESTSDFLQMQSHSYQLPSTFTTHTEWTQDKEQHQHNPQQQATGNRQYSASAFAVSPSYLHASEASQPPKNSLPHPSRDFQPPYY", "length": 436, "header": "tr|Q9W5A7-1|Q9W5A7_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG11381 PE=4 SV=2 CANONICAL=Q9W5A7-1" }, "isoforms": [ { "isoform_ac": "Q9W5A7-1", "url": "https://www.uniprot.org/uniprotkb/Q9W5A7/entry#Q9W5A7-1", "sequence": { "sequence": "MLKAAKIPLFFALLGAVCIQAVVVGPQPLHNNNRNGYRYNGPAHKYLPSEESHSHGSPLDSSHQHDQQGPSNAYNSHHYPAQEQHGQGAPEHDHQQKEVDSWQTALSQQQHESFGNQQNHQNAYNEGPVYQHYQGFNHQQHYGLSQQQQHESYGQEHYQQSPNQLQHHQSQHANEYAYEPAHFQQQQQHHEIQGHKQHQQRKEHWNFVQEQQPQNHEPWQSSHGFQQHQQQHSNRFESQLPLREDLWQPIRELDLEKLPSAEAHASSHKTVAAPGRDVKLVPSYTLSSDFEHDRFIGLDSTDTRLLTQSLPDAYRKQLFSSPPEPSSLAQGHNQQHKPGSAAYGGSHGPSLGESTSDFLQMQSHSYQLPSTFTTHTEWTQDKEQHQHNPQQQATGNRQYSASAFAVSPSYLHASEASQPPKNSLPHPSRDFQPPYY", "length": 436, "header": "tr|Q9W5A7-1|Q9W5A7_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG11381 PE=4 SV=2 CANONICAL=Q9W5A7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W5A7", "url": "https://www.uniprot.org/uniprotkb/Q9W5A7" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W5A7", "url": "https://www.uniprot.org/uniprotkb/Q9W5A7" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W5A7", "url": "https://www.uniprot.org/uniprotkb/Q9W5A7" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W5A7", "url": "https://www.uniprot.org/uniprotkb/Q9W5A7" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W5A7", "url": "https://www.uniprot.org/uniprotkb/Q9W5A7" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W5A7", "url": "https://www.uniprot.org/uniprotkb/Q9W5A7" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W5A7", "url": "https://www.uniprot.org/uniprotkb/Q9W5A7" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W5A7", "url": "https://www.uniprot.org/uniprotkb/Q9W5A7" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W5A7", "url": "https://www.uniprot.org/uniprotkb/Q9W5A7" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W5A7", "url": "https://www.uniprot.org/uniprotkb/Q9W5A7" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W5A7", "url": "https://www.uniprot.org/uniprotkb/Q9W5A7" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG11381", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG11381", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "egg chorion", "id": "GO:0042600", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042600", "evidence": [ { "database": "UniProtKB", "id": "Q9W5A7", "url": "https://www.uniprot.org/uniprotkb/Q9W5A7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9W5A9-1", "uniprot_ac": "Q9W5A9", "uniprot_id": "Q9W5A9_DROME", "mass": { "chemical_mass": 64020.0, "monoisotopic_mass": 64020.0 }, "refseq": { "ac": "NP_001284767", "name": "uncharacterized protein, isoform B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001284767" }, "gene_names": [ { "name": "Dmel\\CG11380", "type": "recommended", "evidence": [ { "id": "Q9W5A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W5A9" } ] }, { "name": "CG11380", "type": "synonym", "evidence": [ { "id": "NP_001284767", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001284767" }, { "id": "Q9W5A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W5A9" } ] }, { "name": "Dmel\\CG11380", "type": "synonym", "evidence": [ { "id": "NP_001284767", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001284767" } ] }, { "name": "Dmel_CG11380", "type": "synonym", "evidence": [ { "id": "Q9W5A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W5A9" } ] }, { "name": "EG:BACR42I17.7", "type": "synonym", "evidence": [ { "id": "NP_001284767", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001284767" }, { "id": "Q9W5A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W5A9" } ] } ], "protein_names": [ { "name": "CG11380-PB", "type": "synonym", "evidence": [ { "id": "NP_001284767", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001284767" } ] }, { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "Q9W5A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W5A9/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein, isoform B", "type": "synonym", "evidence": [ { "id": "NP_001284767", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001284767" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W5A9", "url": "https://www.uniprot.org/uniprotkb/Q9W5A9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG11380", "url": "https://www.uniprot.org/uniprotkb/Q9W5A9", "locus": { "chromosome": "X", "start_pos": 1196660, "end_pos": 1191308, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0040359", "url": "https://www.ensemblgenomes.org/id/FBgn0040359" } ] } } ], "crossref": [ { "id": "FB:FBgn0040359", "url": "https://alliancegenome.org/gene/FB:FBgn0040359", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0040359", "url": "https://bgee.org/?page=gene&gene_id=FBgn0040359", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0040359", "url": "https://flybase.org/reports/FBgn0040359", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "31065", "url": "https://www.ncbi.nlm.nih.gov/gene/31065", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dme:Dmel_CG11380", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG11380", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PPYNYHA", "url": "https://omabrowser.org/oma/group/PPYNYHA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W5A9", "url": "https://www.orthodb.org/?gene=Q9W5A9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "NP_001284767", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001284767", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W5A9", "url": "https://www.uniprot.org/uniprotkb/Q9W5A9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W5A9-1", "url": "https://www.uniprot.org/uniprotkb/Q9W5A9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRLALILGTLSAIVCLASSLSQSEASGSKGNGFPKKVTTLKKRPTKTPTTVPISISRATTLKPSKPRVKIGTSATTKSPTKAPALTETFGNLPADDLEFIKELDKQFKLHGNKIKIKVERDNSTSSGGKNSKRTIEGDLGYGYSHPGYDYTPPKFMFYPYSQHDIPSGFALPQPHPEEQEEEAHQPAMQHHHNHEQVTSVTIEPSYSYELKPQTSYETQPQHTAPEQPQIDLPQDEAESPSGAGGSSGHGGYQEPVIVLRIPGPAKYAAHLQTLLQQYLEIRAAQYLSLLQEADQQQQQQQHQHVDPSQQYGPPEPATYHQEVSYAHQLAPTPAPVQYAPIDDVYQSYKGRHQQQLQLQQQQYEPQQYYAPMDYQQPTQFYYAQPQSHLQQQPQLYLIAMAQPETEPEPQPQQHHHQQHHHHLQQQQQQQQPIYVPESDPPTGPSGGPEQEPEADHSLPITENNPRPTHTKVIFNPYPYQQQQHQPQQQTTNIEEHQHQPEGERPFNYHAHAIKMRQGKRAAKPEPADGDVGPSSGDKGLQQIREYVREKLGAEMGSAVEYKTTQLLEG", "length": 569, "header": "tr|Q9W5A9-1|Q9W5A9_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG11380 PE=4 SV=2 CANONICAL=Q9W5A9-1" }, "isoforms": [ { "isoform_ac": "Q9W5A9-1", "url": "https://www.uniprot.org/uniprotkb/Q9W5A9/entry#Q9W5A9-1", "sequence": { "sequence": "MRLALILGTLSAIVCLASSLSQSEASGSKGNGFPKKVTTLKKRPTKTPTTVPISISRATTLKPSKPRVKIGTSATTKSPTKAPALTETFGNLPADDLEFIKELDKQFKLHGNKIKIKVERDNSTSSGGKNSKRTIEGDLGYGYSHPGYDYTPPKFMFYPYSQHDIPSGFALPQPHPEEQEEEAHQPAMQHHHNHEQVTSVTIEPSYSYELKPQTSYETQPQHTAPEQPQIDLPQDEAESPSGAGGSSGHGGYQEPVIVLRIPGPAKYAAHLQTLLQQYLEIRAAQYLSLLQEADQQQQQQQHQHVDPSQQYGPPEPATYHQEVSYAHQLAPTPAPVQYAPIDDVYQSYKGRHQQQLQLQQQQYEPQQYYAPMDYQQPTQFYYAQPQSHLQQQPQLYLIAMAQPETEPEPQPQQHHHQQHHHHLQQQQQQQQPIYVPESDPPTGPSGGPEQEPEADHSLPITENNPRPTHTKVIFNPYPYQQQQHQPQQQTTNIEEHQHQPEGERPFNYHAHAIKMRQGKRAAKPEPADGDVGPSSGDKGLQQIREYVREKLGAEMGSAVEYKTTQLLEG", "length": 569, "header": "tr|Q9W5A9-1|Q9W5A9_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG11380 PE=4 SV=2 CANONICAL=Q9W5A9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 332, "start_aa": "Thr", "end_pos": 332, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr332", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W5A9", "url": "https://www.uniprot.org/uniprotkb/Q9W5A9" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W5A9", "url": "https://www.uniprot.org/uniprotkb/Q9W5A9" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W5A9", "url": "https://www.uniprot.org/uniprotkb/Q9W5A9" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W5A9", "url": "https://www.uniprot.org/uniprotkb/Q9W5A9" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W5A9", "url": "https://www.uniprot.org/uniprotkb/Q9W5A9" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W5A9", "url": "https://www.uniprot.org/uniprotkb/Q9W5A9" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W5A9", "url": "https://www.uniprot.org/uniprotkb/Q9W5A9" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W5A9", "url": "https://www.uniprot.org/uniprotkb/Q9W5A9" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W5A9", "url": "https://www.uniprot.org/uniprotkb/Q9W5A9" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W5A9", "url": "https://www.uniprot.org/uniprotkb/Q9W5A9" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W5A9", "url": "https://www.uniprot.org/uniprotkb/Q9W5A9" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG11380", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG11380", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 122, "end_pos": 124, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 332 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 122, "end_pos": 124 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", 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"PTHR11960", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11960", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11960:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11960:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01652", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01652", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_726718", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_726718", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W5B3", "url": "https://www.uniprot.org/uniprotkb/Q9W5B3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W5B3-1", "url": "https://www.uniprot.org/uniprotkb/Q9W5B3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLPNSFYRMRDFANPRTMFKSCANNNEYPTQGPQKVESPTDVTQPAAAPQSTEDTQPEKTQEPMNDPNKTSPSEPQKRGKGNRKGKKNQKNAPRTPSQTSKSSRSNNPGKDGKSTGNDDNEKGKGQGKQMVQQKENSPEQEQSTSAQYRKNVLDKDLQDKKLIEKNMQGKIITQENLLGQKVLMRLSEQKLLSLRLEPRIKQNTCPPAKKEDAVVAFDNSLEFLSLNNKCDDDLTIAAENAELLEVEDPQHPLNNCWTLWYLENDRNKSWEEMLHKVTSFDTVEKFWSLITHIKPPSELMLGSDYSLFKKGIRPMWEDEANVNGGRWVINLTKSAKMALDSFWMDAMLCLIGEACKHSDDLCGVVVNIRGKSNKISIWNADGGNQTTVLEIGRILRKVLRMDNIYVLEYQLHKDSKDKLGSTVKRIYTV", "length": 429, "header": "tr|Q9W5B3-1|Q9W5B3_DROME Isoform 1 of eIF-4F 25 kDa subunit OS=Drosophila melanogaster OX=7227 GN=eIF4E7 PE=3 SV=2 CANONICAL=Q9W5B3-1" }, "isoforms": [ { "isoform_ac": "Q9W5B3-1", "url": "https://www.uniprot.org/uniprotkb/Q9W5B3/entry#Q9W5B3-1", "sequence": { "sequence": "MLPNSFYRMRDFANPRTMFKSCANNNEYPTQGPQKVESPTDVTQPAAAPQSTEDTQPEKTQEPMNDPNKTSPSEPQKRGKGNRKGKKNQKNAPRTPSQTSKSSRSNNPGKDGKSTGNDDNEKGKGQGKQMVQQKENSPEQEQSTSAQYRKNVLDKDLQDKKLIEKNMQGKIITQENLLGQKVLMRLSEQKLLSLRLEPRIKQNTCPPAKKEDAVVAFDNSLEFLSLNNKCDDDLTIAAENAELLEVEDPQHPLNNCWTLWYLENDRNKSWEEMLHKVTSFDTVEKFWSLITHIKPPSELMLGSDYSLFKKGIRPMWEDEANVNGGRWVINLTKSAKMALDSFWMDAMLCLIGEACKHSDDLCGVVVNIRGKSNKISIWNADGGNQTTVLEIGRILRKVLRMDNIYVLEYQLHKDSKDKLGSTVKRIYTV", "length": 429, "header": "tr|Q9W5B3-1|Q9W5B3_DROME Isoform 1 of eIF-4F 25 kDa subunit OS=Drosophila melanogaster OX=7227 GN=eIF4E7 PE=3 SV=2 CANONICAL=Q9W5B3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W5B3", "url": "https://www.uniprot.org/uniprotkb/Q9W5B3" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W5B3", "url": "https://www.uniprot.org/uniprotkb/Q9W5B3" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W5B3", "url": "https://www.uniprot.org/uniprotkb/Q9W5B3" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W5B3", "url": "https://www.uniprot.org/uniprotkb/Q9W5B3" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W5B3", "url": "https://www.uniprot.org/uniprotkb/Q9W5B3" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W5B3", "url": "https://www.uniprot.org/uniprotkb/Q9W5B3" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W5B3", "url": "https://www.uniprot.org/uniprotkb/Q9W5B3" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W5B3", "url": "https://www.uniprot.org/uniprotkb/Q9W5B3" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W5B3", "url": "https://www.uniprot.org/uniprotkb/Q9W5B3" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W5B3", "url": "https://www.uniprot.org/uniprotkb/Q9W5B3" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W5B3", "url": "https://www.uniprot.org/uniprotkb/Q9W5B3" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG32859", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG32859", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A3E5-1", "protein_name": "Eukaryotic translation initiation factor 4E", "gene_name": "Eif4e1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLVRPLLLLVLYSSLSCQEVAPDANFPPPSQLQSQCANCQTDYRTQERTLEASLQGRRELEAQMSKAEGEGQEEEEEEEEEEEKEEEEEEEEEEKEEEEEEEVKEKPSEATAEGLQGEARDLPGSLKTVKQKAQREHPTKLPRELHPLQFRWVLWFFKNDRSRAWQDNLQLVTKFDTVEDFWATYRHVKLASKLSCGCDYALFKEGIQPMWEDSRNKRGGRWLLSLAKQQRHMELDRLWLETLLCLLGESFEEYSGEVCGAVVNIRTKGDKIALWTSEAENKAGVMHIGHIYKERLGLSTKTIIGYQAHADTAAKSNSLAKNKFVV", "length": 326 }, "evidence": [ { "id": "MGI:2685119", "url": "https://alliancegenome.org/gene/MGI:2685119#orthology", "database": "AGR" }, { "id": "HGNC:33179", "url": "https://alliancegenome.org/gene/HGNC:33179#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-980526-127", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-980526-127#orthology", "database": "AGR" }, { "id": "FB:FBgn0040368", "url": "https://alliancegenome.org/gene/FB:FBgn0040368#orthology", "database": "AGR" }, { "id": "RGD:1585494", "url": "https://alliancegenome.org/gene/RGD:1585494#orthology", "database": "AGR" }, { "id": "SGD:S000005499", "url": "https://alliancegenome.org/gene/SGD:S000005499#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AC58H109-1", "protein_name": "Eukaryotic translation initiation factor 4E family member 1c isoform X1", "gene_name": "eif4e1c", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MATSEPVRGIGLGSFRASQLPEMRGTETEEVRADSPTAVVTTSPEQYIKHPLQNRWALWYFKNDKSKSWTENLRLISKFDTVEDFWALYNHIQQPSKLGFGCDYCLFKDGIKPMWEDDRNKLGGRWLMTLSKQQRHNDLDRYWMETVIVFFFFFLLGSYILIDSWMCISDCPCVCHLLLQLLCLIGESFDEASEDVCGAVVNVRPKGDKIAIWTGNCQNRDAIMTIGQQYKERLSLPSKTLIGYQSHDDTSSKSGSTTKNMYSV", "length": 264 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050417-398", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-398#orthology", "database": "AGR" }, { "id": "FB:FBgn0040368", "url": "https://alliancegenome.org/gene/FB:FBgn0040368#orthology", "database": "AGR" }, { "id": "SGD:S000005499", "url": "https://alliancegenome.org/gene/SGD:S000005499#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A6NMX2-1", "protein_name": "Eukaryotic translation initiation factor 4E type 1B", "gene_name": "EIF4E1B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLAVEVSEAEGGIREWEEEEKEEEAAERTPTGEKSPNSPRTLLSLRGKARTGGPMEVKLELHPLQNRWALWFFKNDRSRAWQDNLHLVTKVDTVEDFWALYSHIQLASKLSSGCDYALFKDGIQPMWEDSRNKRGGRWLVSLAKQQRHIELDRLWLETLLCLIGESFEEHSREVCGAVVNIRTKGDKIAVWTREAENQAGVLHVGRVYKERLGLSPKTIIGYQAHADTATKSNSLAKNKFVV", "length": 242 }, "evidence": [ { "id": "MGI:2685119", "url": "https://alliancegenome.org/gene/MGI:2685119#orthology", "database": "AGR" }, { "id": "HGNC:33179", "url": "https://alliancegenome.org/gene/HGNC:33179#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-980526-127", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-980526-127#orthology", "database": "AGR" }, { "id": "FB:FBgn0040368", "url": "https://alliancegenome.org/gene/FB:FBgn0040368#orthology", "database": "AGR" }, { "id": "RGD:1585494", "url": "https://alliancegenome.org/gene/RGD:1585494#orthology", "database": "AGR" }, { "id": "SGD:S000005499", "url": "https://alliancegenome.org/gene/SGD:S000005499#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O60573-1", "protein_name": "Eukaryotic translation initiation factor 4E type 2", "gene_name": "EIF4E2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNNKFDALKDDDSGDHDQNEENSTQKDGEKEKTERDKNQSSSKRKAVVPGPAEHPLQYNYTFWYSRRTPGRPTSSQSYEQNIKQIGTFASVEQFWRFYSHMVRPGDLTGHSDFHLFKEGIKPMWEDDANKNGGKWIIRLRKGLASRCWENLILAMLGEQFMVGEEICGAVVSVRFQEDIISIWNKTASDQATTARIRDTLRRVLNLPPNTIMEYKTHTDSIKMPGRLGPQRLLFQNLWKPRLNVP", "length": 245 }, "evidence": [ { "id": "SGD:S000005499", "url": "https://alliancegenome.org/gene/SGD:S000005499#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P06730-1", "protein_name": "Eukaryotic translation initiation factor 4E", "gene_name": "EIF4E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATVEPETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV", "length": 217 }, "evidence": [ { "id": "MGI:95305", "url": "https://alliancegenome.org/gene/MGI:95305#orthology", "database": "AGR" }, { "id": "HGNC:3287", "url": "https://alliancegenome.org/gene/HGNC:3287#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040413-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040413-1#orthology", "database": "AGR" }, { "id": "FB:FBgn0040368", "url": "https://alliancegenome.org/gene/FB:FBgn0040368#orthology", "database": "AGR" }, { "id": "RGD:69647", "url": "https://alliancegenome.org/gene/RGD:69647#orthology", "database": "AGR" }, { "id": "SGD:S000005499", "url": "https://alliancegenome.org/gene/SGD:S000005499#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P07260-1", "protein_name": "Eukaryotic translation initiation factor 4E", "gene_name": "CDC33", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSVEEVSKKFEENVSVDDTTATPKTVLSDSAHFDVKHPLNTKWTLWYTKPAVDKSESWSDLLRPVTSFQTVEEFWAIIQNIPEPHELPLKSDYHVFRNDVRPEWEDEANAKGGKWSFQLRGKGADIDELWLRTLLAVIGETIDEDDSQINGVVLSIRKGGNKFALWTKSEDKEPLLRIGGKFKQVLKLTDDGHLEFFPHSSANGRHPQPSITL", "length": 213 }, "evidence": [ { "id": "MGI:95305", "url": "https://alliancegenome.org/gene/MGI:95305#orthology", "database": "AGR" }, { "id": "MGI:2685119", "url": "https://alliancegenome.org/gene/MGI:2685119#orthology", "database": "AGR" }, { "id": "HGNC:33179", "url": "https://alliancegenome.org/gene/HGNC:33179#orthology", "database": "AGR" }, { "id": "HGNC:3287", "url": "https://alliancegenome.org/gene/HGNC:3287#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-980526-127", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-980526-127#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050417-398", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-398#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040413-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040413-1#orthology", "database": "AGR" }, { "id": "FB:FBgn0040368", "url": "https://alliancegenome.org/gene/FB:FBgn0040368#orthology", "database": "AGR" }, { "id": "RGD:69647", "url": "https://alliancegenome.org/gene/RGD:69647#orthology", "database": "AGR" }, { "id": "RGD:1585494", "url": "https://alliancegenome.org/gene/RGD:1585494#orthology", "database": "AGR" }, { "id": "SGD:S000005499", "url": "https://alliancegenome.org/gene/SGD:S000005499#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P48598-1", "protein_name": "Eukaryotic translation initiation factor 4E1", "gene_name": "eIF4E1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MQSDFHRMKNFANPKSMFKTSAPSTEQGRPEPPTSAAAPAEAKDVKPKEDPQETGEPAGNTATTTAPAGDDAVRTEHLYKHPLMNVWTLWYLENDRSKSWEDMQNEITSFDTVEDFWSLYNHIKPPSEIKLGSDYSLFKKNIRPMWEDAANKQGGRWVITLNKSSKTDLDNLWLDVLLCLIGEAFDHSDQICGAVINIRGKSNKISIWTADGNNEEAALEIGHKLRDALRLGRNNSLQYQLHKDTMVKQGSNVKSIYTL", "length": 259 }, "evidence": [ { "id": "MGI:95305", "url": "https://alliancegenome.org/gene/MGI:95305#orthology", "database": "AGR" }, { "id": "MGI:2685119", "url": "https://alliancegenome.org/gene/MGI:2685119#orthology", "database": "AGR" }, { "id": "HGNC:33179", "url": "https://alliancegenome.org/gene/HGNC:33179#orthology", "database": "AGR" }, { "id": "HGNC:3287", "url": "https://alliancegenome.org/gene/HGNC:3287#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-980526-127", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-980526-127#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050417-398", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-398#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040413-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040413-1#orthology", "database": "AGR" }, { "id": "RGD:69647", "url": "https://alliancegenome.org/gene/RGD:69647#orthology", "database": "AGR" }, { "id": "RGD:1585494", "url": "https://alliancegenome.org/gene/RGD:1585494#orthology", "database": "AGR" }, { "id": "SGD:S000005499", "url": "https://alliancegenome.org/gene/SGD:S000005499#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P63073-1", "protein_name": "Eukaryotic translation initiation factor 4E", "gene_name": "Eif4e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATVEPETTPTTNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV", "length": 217 }, "evidence": [ { "id": "MGI:95305", "url": "https://alliancegenome.org/gene/MGI:95305#orthology", "database": "AGR" }, { "id": "HGNC:3287", "url": "https://alliancegenome.org/gene/HGNC:3287#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040413-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040413-1#orthology", "database": "AGR" }, { "id": "FB:FBgn0040368", "url": "https://alliancegenome.org/gene/FB:FBgn0040368#orthology", "database": "AGR" }, { "id": "RGD:69647", "url": "https://alliancegenome.org/gene/RGD:69647#orthology", "database": "AGR" }, { "id": "SGD:S000005499", "url": "https://alliancegenome.org/gene/SGD:S000005499#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P63074-1", "protein_name": "Eukaryotic translation initiation factor 4E", "gene_name": "Eif4e", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATVEPETTPTTNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV", "length": 217 }, "evidence": [ { "id": "MGI:95305", "url": "https://alliancegenome.org/gene/MGI:95305#orthology", "database": "AGR" }, { "id": "HGNC:3287", "url": "https://alliancegenome.org/gene/HGNC:3287#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040413-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040413-1#orthology", "database": "AGR" }, { "id": "FB:FBgn0040368", "url": "https://alliancegenome.org/gene/FB:FBgn0040368#orthology", "database": "AGR" }, { "id": "RGD:69647", "url": "https://alliancegenome.org/gene/RGD:69647#orthology", "database": "AGR" }, { "id": "SGD:S000005499", "url": "https://alliancegenome.org/gene/SGD:S000005499#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3UTA9-1", "protein_name": "Eukaryotic translation initiation factor 4E type 1B", "gene_name": "Eif4e1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNKVEGGGHKEEVVVKEKEVVKEKPSEATAEGVQAGEAKDLPGSLKTQRRKAHREHPPEVLSKLHPLQYRWVLWFFKNDRSRAWQDNLQLVTKFNTVEDFWAVYSHIKLASKLSSGCDYALFKEGILPMWEDNRNKQGGRWLLSIDKQLRHFELDRLWLETLLCLVGNCFEEYSREVCGAVVNIRTKRDKIALWTSEAEDKAGVMQIGQIYKERLGISTKTIIGYQAHADTAAKSNNLANKFVV", "length": 244 }, "evidence": [ { "id": "MGI:2685119", "url": "https://alliancegenome.org/gene/MGI:2685119#orthology", "database": "AGR" }, { "id": "HGNC:33179", "url": "https://alliancegenome.org/gene/HGNC:33179#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-980526-127", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-980526-127#orthology", "database": "AGR" }, { "id": "FB:FBgn0040368", "url": "https://alliancegenome.org/gene/FB:FBgn0040368#orthology", "database": "AGR" }, { "id": "RGD:1585494", "url": "https://alliancegenome.org/gene/RGD:1585494#orthology", "database": "AGR" }, { "id": "SGD:S000005499", "url": "https://alliancegenome.org/gene/SGD:S000005499#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9DFS6-1", "protein_name": "Eukaryotic translation initiation factor 4E-1A", "gene_name": "eif4ea", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MATAEPETSTNPSNSEEKNEENEQQIVSLEDYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMSGCDYSLFKDGIEPMWEDERNKRGGRWLITLSKQQRRADLDRFWLETLLCLVGEAFDDHSDDVCGAVVNIRTKGDKIAIWTTDYENKDAIVHIGRVYKERLGVPPKVIIGYQSHADTATKSGSTTKNKFVV", "length": 215 }, "evidence": [ { "id": "MGI:95305", "url": "https://alliancegenome.org/gene/MGI:95305#orthology", "database": "AGR" }, { "id": "HGNC:3287", "url": "https://alliancegenome.org/gene/HGNC:3287#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040413-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040413-1#orthology", "database": "AGR" }, { "id": "FB:FBgn0040368", "url": "https://alliancegenome.org/gene/FB:FBgn0040368#orthology", "database": "AGR" }, { "id": "RGD:69647", "url": "https://alliancegenome.org/gene/RGD:69647#orthology", "database": "AGR" }, { "id": "SGD:S000005499", "url": "https://alliancegenome.org/gene/SGD:S000005499#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9PW28-1", "protein_name": "Eukaryotic translation initiation factor 4E-1B", "gene_name": "eif4e1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASCAVQLIDKVPKKKVEKKKFEPNILKEPCMKHPLQNRWGLWFYKNDKSKMWQDNLRLITKFDTVEDFWGLYNNIQLPSKLSSGCDYSMFKDGIEPMWEDRSNKCGGRWLITLAKQHRHTELDHFWLETLLCLIGEGFSSFSRDICGSVINIRAKGDKIALWTSNAENCETVTYIGRKYKESLGLPQKLVIGYQAHADTATKSNSITKNKFVV", "length": 214 }, "evidence": [ { "id": "MGI:2685119", "url": "https://alliancegenome.org/gene/MGI:2685119#orthology", "database": "AGR" }, { "id": "HGNC:33179", "url": "https://alliancegenome.org/gene/HGNC:33179#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-980526-127", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-980526-127#orthology", "database": "AGR" }, { "id": "FB:FBgn0040368", "url": "https://alliancegenome.org/gene/FB:FBgn0040368#orthology", "database": "AGR" }, { "id": "RGD:1585494", "url": "https://alliancegenome.org/gene/RGD:1585494#orthology", "database": "AGR" }, { "id": "SGD:S000005499", "url": "https://alliancegenome.org/gene/SGD:S000005499#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9VAR1-1", "protein_name": "eIF-4F 25 kDa subunit", "gene_name": "eIF4E6", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MENLRQTKESSEFKMGTSLDNNKLASLGATNKHRLQNTWTLWGVKYDPEISWEDMLKEIDSFNTVEDFWNLYFRIDTPSKLNRGCDYMLFKKGIRPMWEDPPNKGGGRWTYKVDKRSTAELDKTWLDVLLCMIGEACDHCDQICGAFVRIRKNINKISVWTKADAGDECNEQC", "length": 173 }, "evidence": [ { "id": "MGI:95305", "url": "https://alliancegenome.org/gene/MGI:95305#orthology", "database": "AGR" }, { "id": "MGI:2685119", "url": "https://alliancegenome.org/gene/MGI:2685119#orthology", "database": "AGR" }, { "id": "HGNC:33179", "url": "https://alliancegenome.org/gene/HGNC:33179#orthology", "database": "AGR" }, { "id": "HGNC:3287", "url": "https://alliancegenome.org/gene/HGNC:3287#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-980526-127", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-980526-127#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050417-398", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-398#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040413-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040413-1#orthology", "database": "AGR" }, { "id": "RGD:69647", "url": "https://alliancegenome.org/gene/RGD:69647#orthology", "database": "AGR" }, { "id": "RGD:1585494", "url": "https://alliancegenome.org/gene/RGD:1585494#orthology", "database": "AGR" }, { "id": "SGD:S000005499", "url": "https://alliancegenome.org/gene/SGD:S000005499#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VRY0-1", "protein_name": "eIF-4F 25 kDa subunit", "gene_name": "eIF4E4", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLTTQQTEFKMMDNGTETLADSPSSSSEDLKTLSDMDIRKPVTEIVDLRLKHPLENTWTLWYLENDRSKNWEDMQNEITSFDMVEDFWSLYNHIKQPSEIRVGSDYSLFKKGIQPMWEDDANKFGGRWVINMGRGSKAELDKLWLDVLLILIGEAFENTEEVCGAVINLRGKSNKISIWTANGHNELAVMEIGLKLRDLLVLPPHQLQYQLHKDTMCKQGSVIKAVYCV", "length": 229 }, "evidence": [ { "id": "MGI:95305", "url": "https://alliancegenome.org/gene/MGI:95305#orthology", "database": "AGR" }, { "id": "MGI:2685119", "url": "https://alliancegenome.org/gene/MGI:2685119#orthology", "database": "AGR" }, { "id": "HGNC:33179", "url": "https://alliancegenome.org/gene/HGNC:33179#orthology", "database": "AGR" }, { "id": "HGNC:3287", "url": "https://alliancegenome.org/gene/HGNC:3287#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-980526-127", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-980526-127#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050417-398", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-398#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040413-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040413-1#orthology", "database": "AGR" }, { "id": "RGD:69647", "url": "https://alliancegenome.org/gene/RGD:69647#orthology", "database": "AGR" }, { "id": "RGD:1585494", "url": "https://alliancegenome.org/gene/RGD:1585494#orthology", "database": "AGR" }, { "id": "SGD:S000005499", "url": "https://alliancegenome.org/gene/SGD:S000005499#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VSB6-1", "protein_name": "eIF-4F 25 kDa subunit", "gene_name": "eIF4E5", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MASAQVQSFDIMKQQDQQHQLNSIHKHHHHHEGVPLESNSPEPIDEEIYQVEYKHPLEHVWTLWYLENDRTKHWKDMLNEITEIDSVETFWSLYHTIKTPAELKIGCDYSVFKKGIKPMWEDEANIKGGRWLVTVSKSAKAELDQIWLDILLLMVGQNFEYSDEICGAVINIRNKSNKISVWTANGSNEMAILEIGQKLKILLHLQSHSLQYQLHSDAMSKFNSGVKSVYTL", "length": 232 }, "evidence": [ { "id": "MGI:95305", "url": "https://alliancegenome.org/gene/MGI:95305#orthology", "database": "AGR" }, { "id": "MGI:2685119", "url": "https://alliancegenome.org/gene/MGI:2685119#orthology", "database": "AGR" }, { "id": "HGNC:33179", "url": "https://alliancegenome.org/gene/HGNC:33179#orthology", "database": "AGR" }, { "id": "HGNC:3287", "url": "https://alliancegenome.org/gene/HGNC:3287#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-980526-127", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-980526-127#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050417-398", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-398#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040413-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040413-1#orthology", "database": "AGR" }, { "id": "RGD:69647", "url": "https://alliancegenome.org/gene/RGD:69647#orthology", "database": "AGR" }, { "id": "RGD:1585494", "url": "https://alliancegenome.org/gene/RGD:1585494#orthology", "database": "AGR" }, { "id": "SGD:S000005499", "url": "https://alliancegenome.org/gene/SGD:S000005499#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VSG1-1", "protein_name": "eIF-4F 25 kDa subunit", "gene_name": "eIF4E3", "tax_id": 7227, "organism": 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"https://www.uniprot.org/uniprotkb/Q9W5C2/entry#names_and_taxonomy" } ] }, { "name": "CG11642-PD", "type": "synonym", "evidence": [ { "id": "NP_001245456", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245456" } ] }, { "name": "TRAM, isoform D", "type": "synonym", "evidence": [ { "id": "NP_001245456", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245456" } ] }, { "name": "TRAM-PD", "type": "synonym", "evidence": [ { "id": "NP_001245456", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245456" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W5C2", "url": "https://www.uniprot.org/uniprotkb/Q9W5C2" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ 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}, { "id": "IPR016447", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016447", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG11642", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG11642", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HGFPELY", "url": "https://omabrowser.org/oma/group/HGFPELY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W5C2", "url": "https://www.orthodb.org/?gene=Q9W5C2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12371", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12371", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12371:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12371:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03798", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03798", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001245456", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001245456", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W5C2", "url": "https://www.uniprot.org/uniprotkb/Q9W5C2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W5C2-1", "url": "https://www.uniprot.org/uniprotkb/Q9W5C2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAIKPGLGRKTSNKNPPILSHEFVIQNHADIISCVAMVFVVGLMNESTAAFASAFISLHHNVSGEDPSREQPYGKPYTYIAGIKDYCAIFFYTLTCIIMHAIIQEFVLDKISKKLHLSKFKLARFNESGQLVAFYLLSFVWGAHVLLKEGYLGQVAQLWEGFPDHPMSFLHKFYFVVQLAYYLHMLPELYFQKIKTKEEQQPKIVHSISGFTLIVLAYTLSFQRLALVLLTLHYFSELLSHVFQLIGVFDREERLAKLRVVNNAVFFLIRFATSVIGVLTLYYGIGGVRSLLALGGLIALQGYLVFSFITEQLRAKREAKKEAKREAKLALQTKKPAKTPKDKVKRKKESDLPEADQTSPSPIKQKLK", "length": 368, "header": "tr|Q9W5C2-1|Q9W5C2_DROME Isoform 1 of Translocating chain-associated membrane protein OS=Drosophila melanogaster OX=7227 GN=TRAM PE=1 SV=1 CANONICAL=Q9W5C2-1" }, "isoforms": [ { "isoform_ac": "Q9W5C2-1", "url": "https://www.uniprot.org/uniprotkb/Q9W5C2/entry#Q9W5C2-1", "sequence": { "sequence": "MAIKPGLGRKTSNKNPPILSHEFVIQNHADIISCVAMVFVVGLMNESTAAFASAFISLHHNVSGEDPSREQPYGKPYTYIAGIKDYCAIFFYTLTCIIMHAIIQEFVLDKISKKLHLSKFKLARFNESGQLVAFYLLSFVWGAHVLLKEGYLGQVAQLWEGFPDHPMSFLHKFYFVVQLAYYLHMLPELYFQKIKTKEEQQPKIVHSISGFTLIVLAYTLSFQRLALVLLTLHYFSELLSHVFQLIGVFDREERLAKLRVVNNAVFFLIRFATSVIGVLTLYYGIGGVRSLLALGGLIALQGYLVFSFITEQLRAKREAKKEAKREAKLALQTKKPAKTPKDKVKRKKESDLPEADQTSPSPIKQKLK", "length": 368, "header": "tr|Q9W5C2-1|Q9W5C2_DROME Isoform 1 of Translocating chain-associated membrane protein OS=Drosophila melanogaster OX=7227 GN=TRAM PE=1 SV=1 CANONICAL=Q9W5C2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W5C2", "url": "https://www.uniprot.org/uniprotkb/Q9W5C2" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W5C2", "url": "https://www.uniprot.org/uniprotkb/Q9W5C2" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W5C2", "url": "https://www.uniprot.org/uniprotkb/Q9W5C2" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W5C2", "url": "https://www.uniprot.org/uniprotkb/Q9W5C2" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W5C2", "url": "https://www.uniprot.org/uniprotkb/Q9W5C2" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W5C2", "url": "https://www.uniprot.org/uniprotkb/Q9W5C2" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W5C2", "url": "https://www.uniprot.org/uniprotkb/Q9W5C2" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W5C2", "url": "https://www.uniprot.org/uniprotkb/Q9W5C2" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W5C2", "url": "https://www.uniprot.org/uniprotkb/Q9W5C2" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W5C2", "url": "https://www.uniprot.org/uniprotkb/Q9W5C2" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W5C2", "url": "https://www.uniprot.org/uniprotkb/Q9W5C2" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG11642", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG11642", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8W4FI69-1", "protein_name": "Translocating chain-associated membrane protein", "gene_name": "TRAM1L1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTFRKKGTKNPPVLSQEFLLQNHADLVACVGMFFVLGLMFEGTAEVSIVFITLQHGVTFPAAEAERATGSKLLYYYGIKDLATVFFYMLVAIIIHATIQEYVLDRINRRMQLPKPKQSKFNESGQFSVFFLVSSIWGTFILVSENCLADLSLLWRAHTHNMMTFQMKFFYISQLAYWFHAFPELYFQRIRQQDLPHQVVYVGLHLFHIAGAYLLYLNHLGLVLLMMHYFVEFLSHVCDLFNFGDEKYQKEFSLWAIVFILGRLATLIVSLITVGFHLAEGQNQNPDATTENVNVLAAKIAVLSSSCTIQAYITWNLFNAQLQWWMEEDIPLQAPSVKKKQRTKCKSSRKGTENGVATSDRVDSPHKRKKNLHDEFQVN", "length": 378 }, "evidence": [ { "id": "Q9W5C2", "url": "https://omabrowser.org/oma/group/Q9W5C2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0ABK0LU55-1", "protein_name": "Translocation associated membrane protein 2", "gene_name": "Tram2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAFRRRTKSYPLFSQEFVIHNHADIVFFLVLCVLIGLMFEVTAKIAFLCILPQYNVSVPTADSETVNYHYGPKDLATILFYILITIILHAVVQEYILDKISKRLHLSKVKHSKFNESGQLVVFHLSSVAWCLYVVATEGYLSNPRSLWEDYPHVYLSLGSALPLHLSKSPGAVPGHTKNSLISSFQVKFFYLGQLAYWLHALPELYFQKVRKEEIPRQLQYICLYLLHIAGAYLLNLSRLGLILLLLQYSTEALFHMARLFYFADENNERLFNAWAAVFGVTRLFIFTLAVLTIGFGLARVENQVFDPEKGNFNTLPCRLGMLLLVCVAQAWLMWRFIHSQLRHWREYWKEQSAKRRVSAVPRLPARLLKREPGFHENGVVKTENGTSSRTKKLKSP", "length": 397 }, "evidence": [ { "id": "HGNC:16855", "url": "https://alliancegenome.org/gene/HGNC:16855#orthology", "database": "AGR" }, { "id": "MGI:1924817", "url": "https://alliancegenome.org/gene/MGI:1924817#orthology", "database": "AGR" }, { "id": "RGD:1589151", "url": "https://alliancegenome.org/gene/RGD:1589151#orthology", "database": "AGR" }, { "id": "FB:FBgn0040340", "url": "https://alliancegenome.org/gene/FB:FBgn0040340#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LZ70-1", "protein_name": "Translocating chain-associated membrane protein", "gene_name": "Tram1l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLRKKNARNPPVLSHEFMVQNHADMVSCVGMFFVLGLMFEGTAEMSIVFLTLQHGVVVPAEGLPSGSRTLYHYGVKDLATVFFYMLVAIIIHATIQEYVLDKLSRRLQLTKGKQNKLNEAGQLSVFYIVSGIWGMIILASENCLSDPTLLWKSQPHNMMTFQMKFFYISQLAYWFHSFPELYFQKVRKQDIPGQLIYIGLHLFHIGGAYLLYLNHLGLLLLMLHYAVELLSSVCSLLYFGDERYQKGLSLWPIVFISGRLVTLIVSVVTVGLHLAGTNRNGNALSGNVNVLAAKIAVLSSSCSIQVYITWTLTTVWLQRWLEDANLHVCGRKRRSRSRKGTENGVENPNRIDSPPKKKEKAP", "length": 363 }, "evidence": [ { "id": "HGNC:28371", "url": "https://alliancegenome.org/gene/HGNC:28371#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q15035-1", "protein_name": "Translocating chain-associated membrane protein 2", "gene_name": "TRAM2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAFRRRTKSYPLFSQEFVIHNHADIGFCLVLCVLIGLMFEVTAKTAFLFILPQYNISVPTADSETVHYHYGPKDLVTILFYIFITIILHAVVQEYILDKISKRLHLSKVKHSKFNESGQLVVFHFTSVIWCFYVVVTEGYLTNPRSLWEDYPHVHLPFQVKFFYLCQLAYWLHALPELYFQKVRKEEIPRQLQYICLYLVHIAGAYLLNLSRLGLILLLLQYSTEFLFHTARLFYFADENNEKLFSAWAAVFGVTRLFILTLAVLAIGFGLARMENQAFDPEKGNFNTLFCRLCVLLLVCAAQAWLMWRFIHSQLRHWREYWNEQSAKRRVPATPRLPARLIKRESGYHENGVVKAENGTSPRTKKLKSP", "length": 370 }, "evidence": [ { "id": "HGNC:16855", "url": "https://alliancegenome.org/gene/HGNC:16855#orthology", "database": "AGR" }, { "id": "MGI:1924817", "url": "https://alliancegenome.org/gene/MGI:1924817#orthology", "database": "AGR" }, { "id": "RGD:1589151", "url": "https://alliancegenome.org/gene/RGD:1589151#orthology", "database": "AGR" }, { "id": "FB:FBgn0040340", "url": "https://alliancegenome.org/gene/FB:FBgn0040340#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q15629-1", "protein_name": "Translocating chain-associated membrane protein 1", "gene_name": "TRAM1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAIRKKSTKSPPVLSHEFVLQNHADIVSCVAMVFLLGLMFEITAKASIIFVTLQYNVTLPATEEQATESVSLYYYGIKDLATVFFYMLVAIIIHAVIQEYMLDKINRRMHFSKTKHSKFNESGQLSAFYLFACVWGTFILISENYISDPTILWRAYPHNLMTFQMKFFYISQLAYWLHAFPELYFQKTKKEDIPRQLVYIGLYLFHIAGAYLLNLNHLGLVLLVLHYFVEFLFHISRLFYFSNEKYQKGFSLWAVLFVLGRLLTLILSVLTVGFGLARAENQKLDFSTGNFNVLAVRIAVLASICVTQAFMMWKFINFQLRRWREHSAFQAPAVKKKPTVTKGRSSKKGTENGVNGTLTSNVADSPRNKKEKSS", "length": 374 }, "evidence": [ { "id": "RGD:1359100", "url": "https://alliancegenome.org/gene/RGD:1359100#orthology", "database": "AGR" }, { "id": "HGNC:20568", "url": "https://alliancegenome.org/gene/HGNC:20568#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-021011-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-021011-1#orthology", "database": "AGR" }, { "id": "MGI:1919515", "url": "https://alliancegenome.org/gene/MGI:1919515#orthology", "database": "AGR" }, { "id": "FB:FBgn0040340", "url": "https://alliancegenome.org/gene/FB:FBgn0040340#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5XI41-1", "protein_name": "Translocating chain-associated membrane protein 1", "gene_name": "Tram1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAIRKKSNKNPPVLSHEFVLQNHADIVSCLAMLFLLGLMFEITAKGAIIFVALQYNVTRPATEEQAAESASLYYYGIKDLATVFFYMLVAIIVHAIIQEYVLDKINRRMHFSKTKHSKFNESGQLSAFYLFACVWGTFILVSENYISDPTILWRAYPHNLMTFQMKFFYISQLAYWLHAFPELYFQKTKKEDIPRQLVYIGLYLFHIAGAYLLNLNHLGLVLLVLHYFVEFLFHISRLFYFSDEKYQKGFSLWAVLFVLGRLLTLILSVLTVGFGLARAENQKLDFSTGNFNVLAVRIAVLASICITQAFMMWKFINFQLRRWREHSAFQAPPVKRKPAVTKGRSSRKGTENGVNGTVTSNGADSPRSRKEKSS", "length": 374 }, "evidence": [ { "id": "RGD:1359100", "url": "https://alliancegenome.org/gene/RGD:1359100#orthology", "database": "AGR" }, { "id": "HGNC:20568", "url": "https://alliancegenome.org/gene/HGNC:20568#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-021011-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-021011-1#orthology", "database": "AGR" }, { "id": "MGI:1919515", "url": "https://alliancegenome.org/gene/MGI:1919515#orthology", "database": "AGR" }, { "id": "FB:FBgn0040340", "url": "https://alliancegenome.org/gene/FB:FBgn0040340#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6P4U7-1", "protein_name": "Translocating chain-associated membrane protein", "gene_name": "tram1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGIRKKTTKNPPVLSHEFVIQNHADIVSCVAMVFLLGLMFEITSKVAVLFITVQYNVTIPANGGPEEATVNYFHYGLKDVATIFFYMLVAIIMHAIIQEYVLDKINRKMHFSKTKHSKFNESGQLSAFYLFSCLWGASILVSENILSNPVSLWDGYPHTLMQFQMKFYYICQLGYWLHAIPELYFQKAKKEDIPRQLVYISLYLVHIAGAYALNLNRLGLVLLVLHYFVELIFHVSRLIYFSNEERQSGFTVWAVLFVLGRLLTLSLSVLTVGFGLAGAEKQGLNLAEGSFNVLFVRVTVLAAICITQAFMMWKFINFQLRRWREQAQTQTLKKKSSSSKSKSKKANGVNGSVGASGADSPRARKEKSS", "length": 369 }, "evidence": [ { "id": "RGD:1359100", "url": "https://alliancegenome.org/gene/RGD:1359100#orthology", "database": "AGR" }, { "id": "HGNC:20568", "url": "https://alliancegenome.org/gene/HGNC:20568#orthology", "database": "AGR" }, { "id": "HGNC:28371", "url": "https://alliancegenome.org/gene/HGNC:28371#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-021011-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-021011-1#orthology", "database": "AGR" }, { "id": "MGI:1919515", "url": "https://alliancegenome.org/gene/MGI:1919515#orthology", "database": "AGR" }, { "id": "MGI:2443503", "url": "https://alliancegenome.org/gene/MGI:2443503#orthology", "database": "AGR" }, { "id": "FB:FBgn0040340", "url": "https://alliancegenome.org/gene/FB:FBgn0040340#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8N609-1", "protein_name": "Translocating chain-associated membrane protein 1-like 1", "gene_name": "TRAM1L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGLRKKSTKNPPVLSQEFILQNHADIVSCVGMFFLLGLVFEGTAEASIVFLTLQHSVAVPAAEEQATGSKSLYYYGVKDLATVFFYMLVAIIIHATIQEYVLDKINKRMQFTKAKQNKFNESGQFSVFYFFSCIWGTFILISENCLSDPTLIWKARPHSMMTFQMKFFYISQLAYWFHAFPELYFQKTKKQDIPRQLVYIGLHLFHITGAYLLYLNHLGLLLLVLHYFVELLSHMCGLFYFSDEKYQKGISLWAIVFILGRLVTLIVSVLTVGFHLAGSQNRNPDALTGNVNVLAAKIAVLSSSCTIQAYVTWNLITLWLQRWVEDSNIQASCMKKKRSRSSKKRTENGVGVETSNRVDCPPKRKEKSS", "length": 369 }, "evidence": [ { "id": "HGNC:28371", "url": "https://alliancegenome.org/gene/HGNC:28371#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-021011-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-021011-1#orthology", "database": "AGR" }, { "id": "MGI:2443503", "url": "https://alliancegenome.org/gene/MGI:2443503#orthology", "database": "AGR" }, { "id": "FB:FBgn0040340", "url": "https://alliancegenome.org/gene/FB:FBgn0040340#orthology", "database": "AGR" }, { "id": "Q9W5C2", "url": "https://omabrowser.org/oma/group/Q9W5C2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8QZR0-1", "protein_name": "Translocating chain-associated membrane protein 1-like 1", "gene_name": "Tram1l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLRKKNARNPPVLSHEFMVQNHADMVSCVGMFFVLGLMFEGTSEMSIAFLTLQHGVVVPAEGLPSGSRTLYHYGVKDLATVFFYMLVAIIIHATIQEYVLDKLSRRLQLTKGKQNKLNEAGQLSVFYIVSGIWGMIILASENCLSDPTLLWKSQPHNMMTFQMKFFYISQLAYWFHSFPELYFQKVRKQDIPGQLIYIGLHLFHIGGAYLLYLNHLGLLLLMLHYAVELLSSVCSLLYFGDERYQKGLSLWPIVFISGRLVTLIVSVVTVGLHLAGTNRNGNALSGNVNVLAAKIAVLSSSCSIQVYITWTLTTVWLQRWLEDANLHVCGRKRRSRARKGTENGVENPNRIDSPPKKKEKAP", "length": 363 }, "evidence": [ { "id": "HGNC:28371", "url": "https://alliancegenome.org/gene/HGNC:28371#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-021011-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-021011-1#orthology", "database": "AGR" }, { "id": "MGI:2443503", "url": "https://alliancegenome.org/gene/MGI:2443503#orthology", "database": "AGR" }, { "id": "FB:FBgn0040340", "url": "https://alliancegenome.org/gene/FB:FBgn0040340#orthology", "database": "AGR" }, { "id": "Q9W5C2", "url": "https://omabrowser.org/oma/group/Q9W5C2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q91V04-1", "protein_name": "Translocating chain-associated membrane protein 1", "gene_name": "Tram1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAIRKKSNKNPPLLSHEFLLQNHADIVSCLAMLFLLGLMFEVTAKGAIIFVALQYNVTRPATEEQATESASLYHYGIKDLATVLFYMLVAIIIHAIIQEYVLDKINRRMHFSKTKHSKFNESGQLSAFYLFACVWGTFILISENYISDPTILWRAYPHNLMTFQTKFFYISQLAYWLHAFPELYFQKTKKEDIPRQLVYIGLYLFHIAGAYLLNLNHLGLVLLVLHYFVEFLFHISRLFYFSDEKYQKGFSLWAVLFVLGRLLTLILSVLTVGFGLARAENQKLDFSTGNFNVLAVRIAVLASICITQAFMMWKFINFQLRRWREHSAFQAPPVKRKPAVTKGRSSRKGTENGVNGTVTSNGADSPRNRKEKSS", "length": 374 }, "evidence": [ { "id": "RGD:1359100", "url": "https://alliancegenome.org/gene/RGD:1359100#orthology", "database": "AGR" }, { "id": "HGNC:20568", "url": "https://alliancegenome.org/gene/HGNC:20568#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-021011-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-021011-1#orthology", "database": "AGR" }, { "id": "MGI:1919515", "url": "https://alliancegenome.org/gene/MGI:1919515#orthology", "database": "AGR" }, { "id": "FB:FBgn0040340", "url": "https://alliancegenome.org/gene/FB:FBgn0040340#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q924Z5-1", "protein_name": "Translocating chain-associated membrane protein 2", "gene_name": "Tram2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"protein insertion into ER membrane", "id": "GO:0045048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045048", "evidence": [ { "database": "UniProtKB", "id": "Q9W5C2", "url": "https://www.uniprot.org/uniprotkb/Q9W5C2" } ], "pmid": "" }, { "name": "SRP-dependent cotranslational protein targeting to membrane, translocation", "id": "GO:0006616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006616", "evidence": [ { "database": "UniProtKB", "id": "Q9W5C2", "url": "https://www.uniprot.org/uniprotkb/Q9W5C2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q9W5C2", "url": "https://www.uniprot.org/uniprotkb/Q9W5C2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 126, "end_pos": 128, "annotation": "n_glycosylation_sequon" }, { "start_pos": 45, "end_pos": 47, 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W5C9" } ] }, { "name": "Dmel\\CG14635", "type": "synonym", "evidence": [ { "id": "NP_569864", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_569864" } ] }, { "name": "Dmel_CG14635", "type": "synonym", "evidence": [ { "id": "Q9W5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W5C9" } ] } ], "protein_names": [ { "name": "CG14635-PA", "type": "synonym", "evidence": [ { "id": "NP_569864", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_569864" } ] }, { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "Q9W5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W5C9/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "NP_569864", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_569864" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W5C9", "url": "https://www.uniprot.org/uniprotkb/Q9W5C9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG14635", "url": "https://www.uniprot.org/uniprotkb/Q9W5C9", "locus": { "chromosome": "X", "start_pos": 845297, "end_pos": 844823, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0029535", "url": "https://www.ensemblgenomes.org/id/FBgn0029535" } ] } } ], "crossref": [ { "id": "FB:FBgn0029535", "url": "https://alliancegenome.org/gene/FB:FBgn0029535", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0029535", "url": "https://bgee.org/?page=gene&gene_id=FBgn0029535", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0029535", "url": "https://flybase.org/reports/FBgn0029535", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "31032", "url": "https://www.ncbi.nlm.nih.gov/gene/31032", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dme:Dmel_CG14635", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG14635", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RYDRIFG", "url": "https://omabrowser.org/oma/group/RYDRIFG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W5C9", "url": "https://www.orthodb.org/?gene=Q9W5C9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "NP_569864", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_569864", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9W5C9", "url": "https://www.uniprot.org/uniprotkb/Q9W5C9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W5C9-1", "url": "https://www.uniprot.org/uniprotkb/Q9W5C9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCSSLSDLFACIRAQGNSDTDSTSTTHRRNIADLDDEAPDLQLQQEQTRKWNDLSMPQRHDSFPVPPPSAGSPSTGYLRPSLRSARVSYEALERYDRIFGRSFQDAGSSGSVRNIPDQF", "length": 119, "header": "tr|Q9W5C9-1|Q9W5C9_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG14635 PE=4 SV=1 CANONICAL=Q9W5C9-1" }, "isoforms": [ { "isoform_ac": "Q9W5C9-1", "url": "https://www.uniprot.org/uniprotkb/Q9W5C9/entry#Q9W5C9-1", "sequence": { "sequence": "MCSSLSDLFACIRAQGNSDTDSTSTTHRRNIADLDDEAPDLQLQQEQTRKWNDLSMPQRHDSFPVPPPSAGSPSTGYLRPSLRSARVSYEALERYDRIFGRSFQDAGSSGSVRNIPDQF", "length": 119, "header": "tr|Q9W5C9-1|Q9W5C9_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG14635 PE=4 SV=1 CANONICAL=Q9W5C9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W5C9", "url": "https://www.uniprot.org/uniprotkb/Q9W5C9" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W5C9", "url": "https://www.uniprot.org/uniprotkb/Q9W5C9" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W5C9", "url": "https://www.uniprot.org/uniprotkb/Q9W5C9" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W5C9", "url": "https://www.uniprot.org/uniprotkb/Q9W5C9" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W5C9", "url": "https://www.uniprot.org/uniprotkb/Q9W5C9" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W5C9", "url": "https://www.uniprot.org/uniprotkb/Q9W5C9" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W5C9", "url": "https://www.uniprot.org/uniprotkb/Q9W5C9" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W5C9", "url": "https://www.uniprot.org/uniprotkb/Q9W5C9" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W5C9", "url": "https://www.uniprot.org/uniprotkb/Q9W5C9" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W5C9", "url": "https://www.uniprot.org/uniprotkb/Q9W5C9" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W5C9", "url": "https://www.uniprot.org/uniprotkb/Q9W5C9" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], 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RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W5W7", "url": "https://www.uniprot.org/uniprotkb/Q9W5W7" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W5W7", "url": "https://www.uniprot.org/uniprotkb/Q9W5W7" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W5W7", "url": "https://www.uniprot.org/uniprotkb/Q9W5W7" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W5W7", "url": "https://www.uniprot.org/uniprotkb/Q9W5W7" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W5W7", "url": "https://www.uniprot.org/uniprotkb/Q9W5W7" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W5W7", "url": "https://www.uniprot.org/uniprotkb/Q9W5W7" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W5W7", "url": "https://www.uniprot.org/uniprotkb/Q9W5W7" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W5W7", "url": "https://www.uniprot.org/uniprotkb/Q9W5W7" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W5W7", "url": "https://www.uniprot.org/uniprotkb/Q9W5W7" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W5W7", "url": "https://www.uniprot.org/uniprotkb/Q9W5W7" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W5W7", "url": "https://www.uniprot.org/uniprotkb/Q9W5W7" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG9581", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG9581", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9SIA3-1", "protein_name": "Xaa-Pro aminopeptidase 3", "gene_name": "XPNPEP3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRWLFSATRLVPAVASARSLSGCLSCSRRRYSLQPIPERRIPNRYLGQPSPFTHPHLLRPGEVTPGLSQVEYALRRHKLMSLIHKEAQEQSGTDHTVVLLSNPTYYMSNDIPYIFHQDNNFLYLCGFQEPDSILVLQSLPGKQLPAHKAMLFVPRRDPSRELWDGPRSGTDGAIALTGVDEAYTLEEFQHLVPKLKAETHTLWYDWMRPAHKQLHCDYMQQLAEVKARSKNKVRAVQQLVQRLRLIKSPAEIERMQVAGKLTSQAFIETMFASKAPVEEGFLYAKFEFECRARGADILAYPPVVAGGNRSNTLHYVKNNQLIKDGEMVLLDGGCESSCYVSDITRTWPVNGRFTAPQAELYEAVLEVQRDCLTLCCPGTSLENVYSMMLTLISQKLKELGITRNIKEKNPFKAARKYCPHHVGHYLGMDVHDTPDMPRSLPLQPGMVITVEPGIYIPEDDQDAPERFRGLGVRIEDDVVVTEASPLVLSADCPKEMKDIEQICSRAS", "length": 507 }, "evidence": [ { "id": "Q9W5W7", "url": "https://omabrowser.org/oma/group/Q9W5W7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "B5DEQ3-1", "protein_name": "Xaa-Pro aminopeptidase 3", "gene_name": "Xpnpep3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSLLSTPRLVPVIARLRGLSGCMSCLQRRYSLQPVPVKEIPNRYLGQPSPVTHPHLLRPGEVTPGLSQVEYALRRHKLMALVHKEAQGHSGTDHTVVVLSNPIHYMSNDIPYTFHQDNSFLYLCGFQEPDSILVLQSCSGKQLPSHKAMLFVPRRDPGRELWDGPRSGTDGAIALTGVDDAYPLEEFQHLLPKLRAETNMVWYDWMKPSHAQLHSDYMQPLTEAKATSKNKVRSVQHLIQHLRLIKSPAEIKRMQIAGKLTSEAFIETMFASKAPVDEAFLYAKFEFECRARGADILAYPPVVAGGNRSNTLHYVKNNQLIKDGEMVLLDGGCESSCYVSDITRTWPVNGRFTAPQAELYEAVLEIQKACLTLCSPGTSLENIYSMMLTLMGQKLKDLGIIKTSKESAFKAARKYCPHHVGHYLGMDVHDTPDMPRSLPLQPGMVITVEPGIYIPEGDTDAPEKFRGLGVRIEDDVVVTQDSPLILSADCPKEVNDIEQICSRTS", "length": 506 }, "evidence": [ { "id": "MGI:2445217", "url": "https://alliancegenome.org/gene/MGI:2445217#orthology", "database": "AGR" }, { "id": "HGNC:28052", "url": "https://alliancegenome.org/gene/HGNC:28052#orthology", "database": "AGR" }, { "id": "FB:FBgn0031093", "url": "https://alliancegenome.org/gene/FB:FBgn0031093#orthology", "database": "AGR" }, { "id": "RGD:1589063", "url": "https://alliancegenome.org/gene/RGD:1589063#orthology", "database": "AGR" }, { "id": "SGD:S000000880", "url": "https://alliancegenome.org/gene/SGD:S000000880#orthology", "database": "AGR" }, { "id": "Q9W5W7", "url": "https://omabrowser.org/oma/group/Q9W5W7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B7ZMP1-1", "protein_name": "Xaa-Pro aminopeptidase 3", "gene_name": "Xpnpep3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPSLLSTPKLAPVLARLRGLSGCMSCLQRRYSLQPAPVKKIPNRYLGQPSPVTHPHLLRPGEVTPGLSQVEYALRRHKLMALVHKEAQGHSGTDHTVVVLSNPTYYMSNDIPYTFHQDNNFLYLCGFQEPDSILVLQSFSGKQLPSHKAMLFVPRRDPGRELWDGPRSGTDGAIALTGVDEAYPLEEFQHLLPKLRAETNMVWYDWMKPSHAQLHSDYMQPLTEAKARSKNKVRSVQQLIQRLRLVKSPSEIKRMQIAGKLTSEAFIETMFASKAPIDEAFLYAKFEFECRARGADILAYPPVVAGGNRSNTLHYVKNNQLIKDGEMVLLDGGCESSCYVSDITRTWPVNGRFTAPQAELYEAVLEIQRACLTLCSPGTSLENIYSMMLTLIGQKLKDLGITKTSKESAFKAARKYCPHHVGHYLGMDVHDTPDMPRSLPLQPGMVITVEPGIYIPEDDRDAPEKFRGLGVRIEDDVVVTQDSPLILSADCPKEMNDIEQICSRTS", "length": 506 }, "evidence": [ { "id": "MGI:2445217", "url": "https://alliancegenome.org/gene/MGI:2445217#orthology", "database": "AGR" }, { "id": "HGNC:28052", "url": "https://alliancegenome.org/gene/HGNC:28052#orthology", "database": "AGR" }, { "id": "FB:FBgn0031093", "url": "https://alliancegenome.org/gene/FB:FBgn0031093#orthology", "database": "AGR" }, { "id": "RGD:1589063", "url": "https://alliancegenome.org/gene/RGD:1589063#orthology", "database": "AGR" }, { "id": "SGD:S000000880", "url": "https://alliancegenome.org/gene/SGD:S000000880#orthology", "database": "AGR" }, { "id": "Q9W5W7", "url": "https://omabrowser.org/oma/group/Q9W5W7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1NH26-1", "protein_name": "Xaa-Pro aminopeptidase 3", "gene_name": "XPNPEP3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSRLPAVVRGWRGLAVCKSCILRRFSIQPAQQKKIPNRYLGQPSPFTHPHLLKPGEVTPGLSQVEYSLRRHKLMALIQKEAQGWEGLDHTVILLSNPTYYMSNDIPYVFHQDTNFLYLCGFQEPDSILVLQSLPGKALPSHKAILFVPRRDPSRELWDGPRSGTDGAVALTGVDEAYTIEEFGHLVAKLKGESNKVWYDVTKPVHKELHSDYMQPLAELKARSKNHIQSIRHLVQNLRLIKSPAEIERMKIAGRVTAEAFVETMFARKSPVDEAFLYAKFEFECRARGADILAYPPVVAGGNRSNTLHYVKNNQLIKDGELVLLDGGCESSCYVSDITRTWPVNGRFTKPQAELYQAVLDIQKSCLSLCSPGVSLENIYSLMLSLIGQKLKDLGILKSSITDSHFFKAVRRYCPHHVGHYLGMDVHDTPDISRSVPLQPGMVITIEPGLYIPEDDVSAPERFRGIGVRIEDDVVIADDSPLILSADCPKEIYDIEQICGRSS", "length": 502 }, "evidence": [ { "id": "Q9W5W7", "url": "https://omabrowser.org/oma/group/Q9W5W7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F4HZG9-1", "protein_name": "Intermediate cleaving peptidase 55, mitochondrial", "gene_name": "ICP55", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MQFLARNLVRRVSRTQVVSRNAYSTQTVRDIGQPTPASHPHLMAEGEVTPGIRIEEYIGRRKKLVELLPENSLAIISSAPVKMMTDVVPYTFRQDADYLYLTGCQQPGGVAVLSDERGLCMFMPESTPKDIAWEGEVAGVDAASEVFKADQAYPISKLPEILSDMIRHSSKVFHNVQSASQRYTNLDDFQNSASLGKVKTLSSLTHELRLIKSPAELKLMRESASIACQGLLKTMLHSKGFPDEGILSAQVEYECRVRGAQRMAFNPVVGGGSNASVIHYSRNDQRIKDGDLVLMDMGCELHGYVSDLTRTWPPCGKFSSVQEELYDLILQTNKECIKQCKPGTTIRQLNTYSTELLCDGLMKMGILKSRRLYHQLNPTSIGHYLGMDVHDSSAVGYDRPLQPGFVITIEPGVYIPSSFDCPERFQGIGIRIEDDVLITETGYEVLTGSMPKEIKHIETLLNNHCHDNSARTSPVSLCKVKGLHTNRNPRRLF", "length": 493 }, "evidence": [ { "id": "Q9W5W7", "url": "https://omabrowser.org/oma/group/Q9W5W7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P40051-1", "protein_name": "Intermediate cleaving peptidase 55", "gene_name": "ICP55", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLHRINPVRFSMQSCQRYFSKLVSPLEQHKSNTFTNRVRIPIEAGQPLHETRPFLIKSGELTPGISALEYYERRIRLAETLPPKSCVILAGNDIQFASGAVFYPFQQENDLFYLSGWNEPNSVMILEKPTDSLSDTIFHMLVPPKDAFAEKWEGFRSGVYGVQEIFNADESASINDLSKYLPKIINRNDFIYFDMLSTSNPSSSNFKHIKSLLDGSGNSNRSLNSIANKTIKPISKRIAEFRKIKSPQELRIMRRAGQISGRSFNQAFAKRFRNERTLDSFLHYKFISGGCDKDAYIPVVATGSNSLCIHYTRNDDVMFDDEMVLVDAAGSLGGYCADISRTWPNSGKFTDAQRDLYEAVLNVQRDCIKLCKASNNYSLHDIHEKSITLMKQELKNLGIDKVSGWNVEKLYPHYIGHNLGLDVHDVPKVSRYEPLKVGQVITIEPGLYIPNEESFPSYFRNVGIRIEDDIAIGEDTYTNLTVEAVKEIDDLENVMQNGLSTKFEEDQVAPL", "length": 511 }, "evidence": [ { "id": "MGI:2445217", "url": "https://alliancegenome.org/gene/MGI:2445217#orthology", "database": "AGR" }, { "id": "HGNC:28052", "url": "https://alliancegenome.org/gene/HGNC:28052#orthology", "database": "AGR" }, { "id": "FB:FBgn0031093", "url": "https://alliancegenome.org/gene/FB:FBgn0031093#orthology", "database": "AGR" }, { "id": "RGD:1589063", "url": "https://alliancegenome.org/gene/RGD:1589063#orthology", "database": "AGR" }, { "id": "SGD:S000000880", "url": "https://alliancegenome.org/gene/SGD:S000000880#orthology", "database": "AGR" }, { "id": "Q9W5W7", "url": "https://omabrowser.org/oma/group/Q9W5W7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54T46-1", "protein_name": "Xaa-Pro aminopeptidase 3", "gene_name": "xpnpep3", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNICKLNKFIISKSSSSLSSTSSKIKTNCLIKNAKMFSSSLNLNRFYSTNNTNNNKLKKPLSIGQATFETHPYLLDKNEITKGIKMKEFKDRREKLMKNFPIGSVVVIFTPPEPMMSYDIPWSFRQNTNFNYLTGFNEPEAVLVLVKTSELDHQSYLFVRERNEEKEKWDGARCGGENVKKYFGIDFGYNLTNRDIPILGKLLKSTTDGKLYCNTTPWNQLSNKLEPFLENIKFYTVESLLQQIRLIKSDAEIKMMLKSGEIAGTSFHETMKYTGTKSSSSSSSSSSSPLNEYQVSAYFEWCVKDKGAQRMSYPPVVAGGDNGHTLHYIQNNQLLNYCDLLLMDAGCEYWGYTSDITRTFPVSGKFTEAQSEVYQAVLDVNKKCIELCKPGETINSIHLKSVELIQAHLKRLGIINESNPNDYRLYYPHSIGHYLGMDTHDTLDFDYGVTLEPGMIITIEPGIYISKYDSNVPEKYRGISIRVEDDVVIPNLNNSPLVLTHLAPKEISEIESIMSNK", "length": 518 }, "evidence": [ { "id": "Q9W5W7", "url": "https://omabrowser.org/oma/group/Q9W5W7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8IPS7-1", "protein_name": "Aminopeptidase P N-terminal domain-containing protein", "gene_name": "Dmel\\CG32454", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLRFLRNFKYYAWQEVRRGCSVVAPPDRSDVLLVLPTVWPSELTKRIRPLSVPDLIEKFSCDAPGGQFATMSEYLRSDPRPDGVLLPDEIDLHRKMSLDDLNSYMHAKDAFKEPHRKNRIFSHVLVVAGADSARSYPFRQRPDFLYLCDCLRPGAALVLTRSRKRNTGALLFLSQDVDSQLSTIFSHMHYVDDVLPLAMLKKSLLWLLRDHSPELWHFYDPSSPVSCIVQEVANEAKIPMGNPRYILQYTRTVKTSRELRALRRANATAADSMAEVIAQHHQIPQELAASFDYKCRLRHARPDVTKTSCGLDGNGLWQMDAGCQYGGYEGGLARCWPSSGRFTPPQKMIYGALLDMRRDLCSLIQYAGCEGAVRTPLELHAAYLILLARHLRELRVLPKGVSSAAETVELARKYNCSPVVVSHVGLGKRDTSRRLLDYPFAPGNVMSLRLSISIPDDCCQAYPEFRGILCQLGDTLHVRDDYSVDLLTAACPSEPQDIEVCLPASRTRSHRLRNDGDQSGSCDTRQLQSHGDGD", "length": 534 }, "evidence": [ { "id": "MGI:2445217", "url": "https://alliancegenome.org/gene/MGI:2445217#orthology", "database": "AGR" }, { "id": "HGNC:28052", "url": "https://alliancegenome.org/gene/HGNC:28052#orthology", "database": "AGR" }, { "id": "RGD:1589063", "url": "https://alliancegenome.org/gene/RGD:1589063#orthology", "database": "AGR" }, { "id": "SGD:S000000880", "url": "https://alliancegenome.org/gene/SGD:S000000880#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9NQH7-1", "protein_name": "Xaa-Pro aminopeptidase 3", "gene_name": "XPNPEP3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPWLLSAPKLVPAVANVRGLSGCMLCSQRRYSLQPVPERRIPNRYLGQPSPFTHPHLLRPGEVTPGLSQVEYALRRHKLMSLIQKEAQGQSGTDQTVVVLSNPTYYMSNDIPYTFHQDNNFLYLCGFQEPDSILVLQSLPGKQLPSHKAILFVPRRDPSRELWDGPRSGTDGAIALTGVDEAYTLEEFQHLLPKMKAETNMVWYDWMRPSHAQLHSDYMQPLTEAKAKSKNKVRGVQQLIQRLRLIKSPAEIERMQIAGKLTSQAFIETMFTSKAPVEEAFLYAKFEFECRARGADILAYPPVVAGGNRSNTLHYVKNNQLIKDGEMVLLDGGCESSCYVSDITRTWPVNGRFTAPQAELYEAVLEIQRDCLALCFPGTSLENIYSMMLTLIGQKLKDLGIMKNIKENNAFKAARKYCPHHVGHYLGMDVHDTPDMPRSLPLQPGMVITIEPGIYIPEDDKDAPEKFRGLGVRIEDDVVVTQDSPLILSADCPKEMNDIEQICSQAS", "length": 507 }, "evidence": [ { "id": "MGI:2445217", "url": "https://alliancegenome.org/gene/MGI:2445217#orthology", "database": "AGR" }, { "id": "HGNC:28052", "url": "https://alliancegenome.org/gene/HGNC:28052#orthology", "database": "AGR" }, { "id": "FB:FBgn0031093", "url": "https://alliancegenome.org/gene/FB:FBgn0031093#orthology", "database": "AGR" }, { "id": "RGD:1589063", "url": "https://alliancegenome.org/gene/RGD:1589063#orthology", "database": "AGR" }, { "id": "SGD:S000000880", "url": "https://alliancegenome.org/gene/SGD:S000000880#orthology", "database": "AGR" }, { "id": "Q9W5W7", "url": "https://omabrowser.org/oma/group/Q9W5W7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q9W5W7", "url": "https://www.uniprot.org/uniprotkb/Q9W5W7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q9W5W7", "url": "https://www.uniprot.org/uniprotkb/Q9W5W7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "manganese ion binding", "id": "GO:0030145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030145", "evidence": [ { "database": "UniProtKB", "id": "Q9W5W7", "url": "https://www.uniprot.org/uniprotkb/Q9W5W7" } ], "pmid": "" }, { "name": "aminopeptidase activity", "id": "GO:0004177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004177", "evidence": [ { "database": "UniProtKB", "id": "Q9W5W7", "url": "https://www.uniprot.org/uniprotkb/Q9W5W7" } ], "pmid": "" }, { "name": "metalloaminopeptidase activity", "id": "GO:0070006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070006", "evidence": [ { "database": "UniProtKB", "id": "Q9W5W7", "url": "https://www.uniprot.org/uniprotkb/Q9W5W7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 316, "end_pos": 318, "annotation": "n_glycosylation_sequon" }, { "start_pos": 331, "end_pos": 333, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9W5W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W5W7" }, { "id": "SM01011", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Aminopeptidase P N-terminal", "eco_id": "ECO_0000259", "start_pos": 88, "end_pos": 238, "start_aa": "Val", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], 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M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9XYZ9", "url": "https://www.uniprot.org/uniprotkb/Q9XYZ9" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9XYZ9", "url": "https://www.uniprot.org/uniprotkb/Q9XYZ9" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9XYZ9", "url": "https://www.uniprot.org/uniprotkb/Q9XYZ9" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9XYZ9", "url": "https://www.uniprot.org/uniprotkb/Q9XYZ9" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9XYZ9", "url": "https://www.uniprot.org/uniprotkb/Q9XYZ9" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9XYZ9", "url": "https://www.uniprot.org/uniprotkb/Q9XYZ9" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9XYZ9", "url": "https://www.uniprot.org/uniprotkb/Q9XYZ9" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9XYZ9", "url": "https://www.uniprot.org/uniprotkb/Q9XYZ9" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9XYZ9", "url": "https://www.uniprot.org/uniprotkb/Q9XYZ9" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9XYZ9", "url": "https://www.uniprot.org/uniprotkb/Q9XYZ9" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9XYZ9", "url": "https://www.uniprot.org/uniprotkb/Q9XYZ9" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG16936", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG16936", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1W2PR19-1", "protein_name": "Glutathione S-transferase theta-4", "gene_name": "GSTT4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALELYMDLLSAPCRAVYIFSKKHDIQFNFQFVDLLKGHHHSKGYIDINPLRKLPSLKDGKFILSESAAILYYLCRKYSAPSHWCPPDPHARARVDEFVAWQHTAFQLPMKKIVWLKLLIPKITGEEVSAEKMEHAVEEVKNSLQLFEEYFLQDKMFITGNQISLADLVAVVEMMQPMAANYNVFLNSSKLAEWRMQVELNIGSGLFREAHDRLMQLADWDFSTLDSMVKENISELLKKSR", "length": 241 }, "evidence": [ { "id": "SGD:S000003983", "url": "https://alliancegenome.org/gene/SGD:S000003983#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A1ZB68-1", "protein_name": "2.5.1.18", "gene_name": "GstE3", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGKLTLYGIDGSPPVRSVLLTLRALNLDFDYKIVNLMEKEHLKPEFLKINPLHTVPALDDNGFYLADSHAINSYLVSKYGRNDSLYPKDLKKRAIVDQRLHYDSSVVTSTGRAITFPLFWENKTEIPQARIDALEGVYKSLNLFLENGNYLAGDNLTIADFHVIAGLTGFFVFLPVDATKYPELAAWIKRIKELPYYEEANGSRAAQIIEFIKSKKFTIV", "length": 220 }, "evidence": [ { "id": "SGD:S000005173", "url": "https://alliancegenome.org/gene/SGD:S000005173#orthology", "database": "AGR" }, { "id": "SGD:S000003983", "url": "https://alliancegenome.org/gene/SGD:S000003983#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A1ZB69-1", "protein_name": "2.5.1.18", "gene_name": "GstE4", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGKISLYGLDASPPTRACLLTLKALDLPFEFVFVNLFEKENFSEDFSKKNPQHTVPLLQDDDACIWDSHAIMAYLVEKYAPSDELYPKDLLQRAKVDQLMHFESGVIFESALRRLTRPVLFFGEPTLPRNQVDHILQVYDFVETFLDDHDFVAGDQLTIADFSIVSTITSIGVFLELDPAKYPKIAAWLERLKELPYYEEANGKGAAQFVELLRSKNFTIVS", "length": 222 }, "evidence": [ { "id": "SGD:S000005173", "url": "https://alliancegenome.org/gene/SGD:S000005173#orthology", "database": "AGR" }, { "id": "SGD:S000003983", "url": "https://alliancegenome.org/gene/SGD:S000003983#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A1ZB70-1", "protein_name": "2.5.1.18", "gene_name": "GstE5", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVKLTLYGVNPSPPVRAVKLTLAALQLPYEFVNVNISGQEQLSEEYLKKNPEHTVPTLEDDGNYIWDSHAIIAYLVSKYADSDALYPRDLLQRAVVDQRLHFETGVVFANGIKAITKPLFFNGLNRIPKERYDAIVEIYDFVETFLAGHDYIAGDQLTIADFSLISSITSLVAFVEIDRLKYPRIIEWVRRLEKLPYYEEANAKGARELETILKSTNFTFAT", "length": 222 }, "evidence": [ { "id": "SGD:S000005173", "url": "https://alliancegenome.org/gene/SGD:S000005173#orthology", "database": "AGR" }, { "id": "SGD:S000003983", "url": "https://alliancegenome.org/gene/SGD:S000003983#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A1ZB71-1", "protein_name": "1.11.1.9", "gene_name": "GstE6", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVKLTLYGLDPSPPVRAVKLTLAALNLTYEYVNVDIVARAQLSPEYLEKNPQHTVPTLEDDGHYIWDSHAIIAYLVSKYADSDALYPKDPLKRAVVDQRLHFESGVVFANGIRSISKSVLFQGQTKVPKERYDAIIEIYDFVETFLKGQDYIAGNQLTIADFSLVSSVASLEAFVALDTTKYPRIGAWIKKLEQLPYYEEANGKGVRQLVAIFKKTNFTFEA", "length": 222 }, "evidence": [ { "id": "SGD:S000003983", "url": "https://alliancegenome.org/gene/SGD:S000003983#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A1ZB72-1", "protein_name": "1.11.1.9", "gene_name": "GstE7", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPKLILYGLEASPPVRAVKLTLAALEVPYEFVEVNTRAKENFSEEFLKKNPQHTVPTLEDDGHYIWDSHAIIAYLVSKYGKTDSLYPKDLLQRAVVDQRLHFESGVIFANALRSITKPLFAGKQTMIPKERYDAIIEVYDFLEKFLAGNDYVAGNQLTIADFSIISTVSSLEVFVKVDTTKYPRIAAWFKRLQKLPYYEEANGNGARTFESFIREYNFTFASN", "length": 223 }, "evidence": [ { "id": "SGD:S000005173", "url": "https://alliancegenome.org/gene/SGD:S000005173#orthology", "database": "AGR" }, { "id": "SGD:S000003983", "url": "https://alliancegenome.org/gene/SGD:S000003983#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A1ZB73-1", "protein_name": "Glutathione S transferase E8, isoform B", "gene_name": "GstE8", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSKLILYGTEASPPVRAAKLTLAALGIPYEYVKINTLAKETLSPEFLRKNPQHTVPTLEDDGHFIWDSHAISAYLVSKYGQSDTLYPKDLLQRAVVDQRLHFESGVVFVNGLRGITKPLFATGQTTIPKERYDAVIEIYDFVETFLTGHDFIAGDQLTIADFSLITSITALAVFVVIDTVKYANITAWIKRIEELPYYEEACGKGARDLVTLLKKFNFTFST", "length": 222 }, "evidence": [ { "id": "SGD:S000003983", "url": "https://alliancegenome.org/gene/SGD:S000003983#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "B7Z0S9-1", "protein_name": "1.11.1.9", "gene_name": "GstD11", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSDTKRIVTEFVYCLLLRGGKMSPPVLYYLPPSPPCRSILLLAKMLDIDFELKIVNILEGEQLKPDFVAMNPQHCVPTMNDEGLVLWESRAILSYLVAAYGKSDQLYPTDIRVRALVDQRLQFDLGTLYMRLTDYYFPTMFIGAPLDEGKRAKLAEAVGWLNTILEGRQFSAADHFTIADLTLLVTVSQLEAFEFELRPYKHIRQWLDRCKDHMAPFDYEELNANKANMLADMFKAKMNQSAG", "length": 243 }, "evidence": [ { "id": "SGD:S000005173", "url": "https://alliancegenome.org/gene/SGD:S000005173#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P0CG29-1", "protein_name": "Glutathione S-transferase theta-2", "gene_name": "GSTT2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGLELFLDLVSQPSRAVYIFAKKNGIPLELRTVDLVKGQHKSKEFLQINSLGKLPTLKDGDFILTESSAILIYLSCKYQTPDHWYPSDLQARARVHEYLGWHADCIRGTFGIPLWVQVLGPLIGVQVPKEKVERNRTAMDQALQWLEDKFLGDRPFLAGQQVTLADLMALEELMQPVALGYELFEGRPRLAAWRGRVEAFLGAELCQEAHSIILSILEQAAKKTLPTPSPEAYQAMLLRIARIP", "length": 244 }, "evidence": [ { "id": "SGD:S000003983", "url": "https://alliancegenome.org/gene/SGD:S000003983#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0CG30-1", "protein_name": "Glutathione S-transferase theta-2B", "gene_name": "GSTT2B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGLELFLDLVSQPSRAVYIFAKKNGIPLELRTVDLVKGQHKSKEFLQINSLGKLPTLKDGDFILTESSAILIYLSCKYQTPDHWYPSDLQARARVHEYLGWHADCIRGTFGIPLWVQVLGPLIGVQVPEEKVERNRTAMDQALQWLEDKFLGDRPFLAGQQVTLADLMALEELMQPVALGYELFEGRPRLAAWRGRVEAFLGAELCQEAHSIILSILEQAAKKTLPTPSPEAYQAMLLRIARIP", "length": 244 }, "evidence": [ { "id": "SGD:S000003983", "url": "https://alliancegenome.org/gene/SGD:S000003983#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P20432-1", "protein_name": "Glutathione S-transferase D1", "gene_name": "GstD1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVDFYYLPGSSPCRSVIMTAKAVGVELNKKLLNLQAGEHLKPEFLKINPQHTIPTLVDNGFALWESRAIQVYLVEKYGKTDSLYPKCPKKRAVINQRLYFDMGTLYQSFANYYYPQVFAKAPADPEAFKKIEAAFEFLNTFLEGQDYAAGDSLTVADIALVATVSTFEVAKFEISKYANVNRWYENAKKVTPGWEENWAGCLEFKKYFE", "length": 209 }, "evidence": [ { "id": "SGD:S000005173", "url": "https://alliancegenome.org/gene/SGD:S000005173#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P23202-1", "protein_name": "Transcriptional regulator URE2", "gene_name": "URE2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MMNNNGNQVSNLSNALRQVNIGNRNSNTTTDQSNINFEFSTGVNNNNNNNSSSNNNNVQNNNSGRNGSQNNDNENNIKNTLEQHRQQQQAFSDMSHVEYSRITKFFQEQPLEGYTLFSHRSAPNGFKVAIVLSELGFHYNTIFLDFNLGEHRAPEFVSVNPNARVPALIDHGMDNLSIWESGAILLHLVNKYYKETGNPLLWSDDLADQSQINAWLFFQTSGHAPMIGQALHFRYFHSQKIASAVERYTDEVRRVYGVVEMALAERREALVMELDTENAAAYSAGTTPMSQSRFFDYPVWLVGDKLTIADLAFVPWNNVVDRIGINIKIEFPEVYKWTKHMMRRPAVIKALRGE", "length": 354 }, "evidence": [ { "id": "FB:FBgn0027590", "url": "https://alliancegenome.org/gene/FB:FBgn0027590#orthology", "database": "AGR" }, { "id": "SGD:S000005173", "url": "https://alliancegenome.org/gene/SGD:S000005173#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P30711-1", "protein_name": "Glutathione S-transferase theta-1", "gene_name": "GSTT1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGLELYLDLLSQPCRAVYIFAKKNDIPFELRIVDLIKGQHLSDAFAQVNPLKKVPALKDGDFTLTESVAILLYLTRKYKVPDYWYPQDLQARARVDEYLAWQHTTLRRSCLRALWHKVMFPVFLGEPVSPQTLAATLAELDVTLQLLEDKFLQNKAFLTGPHISLADLVAITELMHPVGAGCQVFEGRPKLATWRQRVEAAVGEDLFQEAHEVILKAKDFPPADPTIKQKLMPWVLAMIR", "length": 240 }, "evidence": [ { "id": "SGD:S000003983", "url": "https://alliancegenome.org/gene/SGD:S000003983#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q12390-1", "protein_name": "Glutathione S-transferase 2", "gene_name": "GTT2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MNGRGFLIYNGGEKMKQKMIIYDTPAGPYPARVRIALAEKNMLSSVQFVRINLWKGEHKKPEFLAKNYSGTVPVLELDDGTLIAECTAITEYIDALDGTPTLTGKTPLEKGVIHMMNKRAELELLDPVSVYFHHATPGLGPEVELYQNKEWGLRQRDKALHGMHYFDTVLRERPYVAGDSFSMADITVIAGLIFAAIVKLQVPEECEALRAWYKRMQQRPSVKKLLEIRSKSS", "length": 233 }, "evidence": [ { "id": "FB:FBgn0027590", "url": "https://alliancegenome.org/gene/FB:FBgn0027590#orthology", "database": "AGR" }, { "id": "SGD:S000003983", "url": "https://alliancegenome.org/gene/SGD:S000003983#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q64471-1", "protein_name": "Glutathione S-transferase theta-1", "gene_name": "Gstt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLELYLDLLSQPCRAIYIFAKKNNIPFQMHTVELRKGEHLSDAFARVNPMKRVPAMMDGGFTLCESVAILLYLAHKYKVPDHWYPQDLQARARVDEYLAWQHTGLRRSCLRALWHKVMFPVFLGEQIPPETLAATLAELDVNLQVLEDKFLQDKDFLVGPHISLADLVAITELMHPVGGGCPVFEGHPRLAAWYQRVEAAVGKDLFREAHEVILKVKDCPPADLIIKQKLMPRVLAMIQ", "length": 240 }, "evidence": [ { "id": "SGD:S000005173", "url": "https://alliancegenome.org/gene/SGD:S000005173#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7JYX0-1", "protein_name": "Glutathione S-transferase E14", "gene_name": "GstE14", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSQPKPILYYDERSPPVRSCLMLIKLLDIDVELRFVNLFKGEQFQKDFLALNPQHSVPTLVHGDLVLTDSHAILIHLAEKFDEGGSLWPQEHAERMKVLNLLLFECSFLFRRDSDFMSATVRQGFANVDVAHHERKLTEAYIIMERYLENSDFMAGPQLTLADLSIVTTLSTVNLMFPLSQFPRLRRWFTAMQQLDAYEANCSGLEKLRQTMESVGSFQFPSSSAVVTEKVE", "length": 232 }, "evidence": [ { "id": "SGD:S000005173", "url": "https://alliancegenome.org/gene/SGD:S000005173#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VG92-1", "protein_name": "1.11.1.9", "gene_name": "GstD8", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDFYYHPCSAPCRSVIMTAKALGVDLNMKLLKVMDGEQLKPEFVKLNPQHCIPTLVDDGFSIWESRAILIYLVEKYGADDSLYPSDPQKKAVVNQRLYFDMGTLFQSFVEAIYPQIRNNHPADPEAMQKVDSAFGHLDTFLEDQEYVAGDCLTIADIALLASVSTFEVVDFDIAQYPNVARWYENAKEVTPGWEENWDGVQLIKKLVQERNE", "length": 212 }, "evidence": [ { "id": "SGD:S000005173", "url": "https://alliancegenome.org/gene/SGD:S000005173#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VG93-1", "protein_name": "Glutathione S-transferase D7", "gene_name": "GstD7", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPNLDLYNFPMAPASRAIQMVAKALGLELNSKLINTMEGDQLKPEFVRINPQHTIPTLVDNGFVIWESRAIAVYLVEKYGKPDSPLYPNDPQKRALINQRLYFDMGTLYDALTKYFFLIFRTGKFGDQEALDKVNSAFGFLNTFLEGQDFVAGSQLTVADIVILATVSTVEWFSFDLSKFPNVERWLKNAPKVTPGWEQNLESLQQGKKFLQDLQAAKEKEVKA", "length": 224 }, "evidence": [ { "id": "SGD:S000005173", "url": "https://alliancegenome.org/gene/SGD:S000005173#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VG94-1", "protein_name": "Glutathione S-transferase D6", "gene_name": "GstD6", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDLYNMSGSPSTRAVMMTAKAVGVEFNSIQVNTFVGEQLEPWFVKINPQHTIPTLVDNLFVIWETRAIVVYLVEQYGKDDSLYPKDPQKQALINQRLYFDMGTLYDGIAKYFFPLLRTGKPGTQENLEKLNAAFDLLNNFLDGQDYVAGNQLSVADIVILATVSTTEMVDFDLKKFPNVDRWYKNAQKVTPGWDENLARIQSAKKFLAENLIEKL", "length": 215 }, "evidence": [ { "id": "SGD:S000005173", "url": "https://alliancegenome.org/gene/SGD:S000005173#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VG95-1", "protein_name": "Glutathione S-transferase D5", "gene_name": "GstD5", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDFYYSPRGSGCRTVIMVAKALGVKLNMKLLNTLEKDQLKPEFVKLNPQHTIPTLVDNGFSIWESRAIAVYLVEKYGKDDTLFPKDPKKQALVNQRLYFDMGTLYDSFAKYYYPLFHTGKPGSDEDFKKIESSFEYLNIFLEGQNYVAGDHLTVADIAILSTVSTFEIFDFDLNKYPNVARWYANAKKVTPGWEENWKGAVELKGVFDARQAAAKQ", "length": 216 }, "evidence": [ { "id": "SGD:S000005173", "url": "https://alliancegenome.org/gene/SGD:S000005173#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VG96-1", "protein_name": "Glutathione S-transferase D4", "gene_name": "GstD4", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDFYYSPRSSGSRTIIMVAKALGLELNKKQLRITEGEHLKPEFLKLNPQHTIPTLVDNGFAIWESRAIAVYLVEKYGKDDSLFPNDPQKRALINQRLYFDMGTLHDSFMKYYYPFIRTGQLGNAENYKKVEAAFEFLDIFLEGQDYVAGSQLTVADIAILSSVSTFEVVEFDISKYPNVARWYANAKKITPGWDENWKGLLQMKTMYEAQKASLK", "length": 215 }, "evidence": [ { "id": "SGD:S000005173", "url": "https://alliancegenome.org/gene/SGD:S000005173#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VG97-1", "protein_name": "Inactive glutathione S-transferase D3", "gene_name": "GstD3", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVGKALGLEFNKKIINTLKGEQMNPDFIKINPQHSIPTLVDNGFTIWESRAILVYLVEKYGKDDALYPKDIQKQAVINQRLYFDMALMYPTLANYYYKAFTTGQFGSEEDYKKVQETFDFLNTFLEGQDYVAGDQYTVADIAILANVSNFDVVGFDISKYPNVARWYDHVKKITPGWEENWAGALDVKKRIEEKQNAAK", "length": 199 }, "evidence": [ { "id": "SGD:S000005173", "url": "https://alliancegenome.org/gene/SGD:S000005173#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VG98-1", "protein_name": "Glutathione S-transferase D2", "gene_name": "GstD2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDFYYMPGGGGCRTVIMVAKALGLELNKKLLNTMEGEQLKPEFVKLNPQHTIPTLVDNGFSIWESRAIAVYLVEKYGKDDYLLPNDPKKRAVINQRLYFDMGTLYESFAKYYYPLFRTGKPGSDEDLKRIETAFGFLDTFLEGQEYVAGDQLTVADIAILSTVSTFEVSEFDFSKYSNVSRWYDNAKKVTPGWDENWEGLMAMKALFDARKLAAK", "length": 215 }, "evidence": [ { "id": "SGD:S000005173", "url": "https://alliancegenome.org/gene/SGD:S000005173#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VGA0-1", "protein_name": "Glutathione S transferase D9, isoform A", "gene_name": "GstD9", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLDFYYMLYSAPCRSILMTARALGLELNKKQVDLDAGEHLKPEFVKINPQHTIPTLVDDGFAIWESRAILIYLAEKYDKDGSLYPKDPQQRAVINQRLFFDLSTLYQSYVYYYYPQLFEDVKKPADPDNLKKIDDAFAMFNTLLKGQQYAALNKLTLADFALLATVSTFEISEYDFGKYPEVVRWYDNAKKVIPGWEENWEGCEYYKKLYLGAILNKQ", "length": 218 }, "evidence": [ { "id": "SGD:S000005173", "url": "https://alliancegenome.org/gene/SGD:S000005173#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VGA1-1", "protein_name": "Glutathione S transferase D10, isoform B", "gene_name": "GstD10", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDLYYRPGSAPCRSVLMTAKALGVEFDKKTIINTRAREQFTPEYLKINPQHTIPTLHDHGFALWESRAIMVYLVEKYGKDDKLFPKDVQKQALINQRLYFDMGTLYKSFSEYYYPQIFLKKPANEENYKKIEVAFEFLNTFLEGQTYSAGGDYSLADIAFLATVSTFDVAGFDFKRYANVARWYENAKKLTPGWEENWAGCQEFRKYFDN", "length": 210 }, "evidence": [ { "id": "SGD:S000005173", "url": "https://alliancegenome.org/gene/SGD:S000005173#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "glutathione transferase activity", "id": "GO:0004364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004364", "evidence": [ { "database": "UniProtKB", "id": "Q9XYZ9", "url": "https://www.uniprot.org/uniprotkb/Q9XYZ9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9XYZ9", "url": "https://www.uniprot.org/uniprotkb/Q9XYZ9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "glutathione metabolic process", "id": "GO:0006749", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006749", "evidence": [ { "database": "UniProtKB", "id": "Q9XYZ9", "url": "https://www.uniprot.org/uniprotkb/Q9XYZ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9XYZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9XYZ9" }, { "id": "PS50405", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50405" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GST C-terminal", "eco_id": "ECO_0000259", "start_pos": 90, "end_pos": 213, "start_aa": "Glu", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q9XYZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9XYZ9" }, { "id": "PS50404", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50404" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GST N-terminal", "eco_id": "ECO_0000259", "start_pos": 2, "end_pos": 83, "start_aa": "Ser", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.5.1.18", "ec_name": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "2.5.1.18", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.18" }, { "id": "2.5.1.18", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.5.1.18" } ] } ], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 172, "end_pos": 174 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9XZ68-1", "uniprot_ac": "Q9XZ68", "uniprot_id": "Q9XZ68_DROME", "mass": { "chemical_mass": 38542.0, "monoisotopic_mass": 38542.0 }, "refseq": { "ac": "NP_524894", "name": "Rab geranylgeranyltransferase subunit beta", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524894" }, "gene_names": [ { "name": "RabGGTb", "type": "recommended", "evidence": [ { "id": "Q9XZ68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9XZ68" } ] }, { "name": "CG18627", "type": "synonym", "evidence": [ { "id": "NP_524894", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524894" }, { "id": "Q9XZ68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9XZ68" } ] }, { "name": "Dmel\\CG18627", "type": "synonym", "evidence": [ { "id": "NP_524894", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524894" }, { "id": "Q9XZ68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9XZ68" } ] }, { "name": "Dmel_CG18627", "type": "synonym", "evidence": [ { "id": "Q9XZ68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9XZ68" } ] }, { "name": "GGT-II beta", "type": "synonym", "evidence": [ { "id": "NP_524894", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524894" }, { "id": "Q9XZ68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9XZ68" } ] }, { "name": "RabGGTbeta", "type": "synonym", "evidence": [ { "id": "NP_524894", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524894" }, { "id": "Q9XZ68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9XZ68" } ] }, { "name": "RabGGTb", "type": "synonym", "evidence": [ { "id": "NP_524894", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524894" } ] }, { "name": "beta-ggt-II", "type": "synonym", "evidence": [ { "id": "Q9XZ68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9XZ68" } ] }, { "name": "betaggt II", "type": "synonym", "evidence": [ { "id": "NP_524894", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524894" }, { "id": "Q9XZ68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9XZ68" } ] }, { "name": "betaggt-II", "type": "synonym", "evidence": [ { "id": "NP_524894", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524894" }, { "id": "Q9XZ68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9XZ68" } ] }, { "name": "betaggt", "type": "synonym", "evidence": [ { "id": "NP_524894", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524894" }, { "id": "Q9XZ68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9XZ68" } ] } ], "protein_names": [ { "name": "Geranylgeranyl transferase type-2 subunit beta", "type": "recommended", "evidence": [ { "id": "Q9XZ68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9XZ68/entry#names_and_taxonomy" } ] }, { "name": "2.5.1.60", "type": "synonym", "evidence": [ { "id": "Q9XZ68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9XZ68/entry#names_and_taxonomy" } ] }, { "name": "CG18627-PA", "type": "synonym", "evidence": [ { "id": "NP_524894", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524894" } ] }, { "name": "Rab geranylgeranyltransferase subunit beta", "type": "synonym", "evidence": [ { "id": "NP_524894", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524894" } ] }, { "name": "RabGGTb-PA", "type": "synonym", "evidence": [ { "id": "NP_524894", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524894" } ] }, { "name": "beta subunit of type II geranylgeranyl transferase", "type": "synonym", "evidence": [ { "id": "NP_524894", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524894" } ] } ], "function": [ { "annotation": "Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX.", "evidence": [ { "database": "UniProtKB", "id": "Q9XZ68", "url": "https://www.uniprot.org/uniprotkb/Q9XZ68#function" }, { "database": "UniProtKB", "id": "RU365076", "url": "https://www.uniprot.org/uniprotkb/RU365076#function" }, { "database": "UniProtKB", "id": "ARBA00094457", "url": "https://www.uniprot.org/uniprotkb/ARBA00094457#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9XZ68", "url": "https://www.uniprot.org/uniprotkb/Q9XZ68" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "RabGGTb", "url": "https://www.uniprot.org/uniprotkb/Q9XZ68", "locus": { "chromosome": "2L", "start_pos": 2880708, "end_pos": 2879112, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0028970", "url": "https://www.ensemblgenomes.org/id/FBgn0028970" } ] } } ], "crossref": [ { "id": "FB:FBgn0028970", "url": "https://alliancegenome.org/gene/FB:FBgn0028970", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0028970", "url": "https://bgee.org/?page=gene&gene_id=FBgn0028970", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02894", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02894", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0028970", "url": "https://flybase.org/reports/FBgn0028970", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "47757", "url": "https://www.ncbi.nlm.nih.gov/gene/47757", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001330", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001330", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008930", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008930", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026873", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026873", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045089", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045089", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG18627", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG18627", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VKRCQCP", "url": "https://omabrowser.org/oma/group/VKRCQCP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9XZ68", "url": "https://www.orthodb.org/?gene=Q9XZ68", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11774", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11774", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11774:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11774:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00432", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00432", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-6803205", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6803205", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-8873719", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8873719", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_524894", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_524894", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "21240", "url": "https://www.rhea-db.org/rhea/21240", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q9XZ68", "url": "https://www.uniprot.org/uniprotkb/Q9XZ68", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9XZ68-1", "url": "https://www.uniprot.org/uniprotkb/Q9XZ68-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDFTTFVKPSNGGGDSGGGGDADGGGQKLQFWKHVEYIENHGKQEDDYEYCMTEFLRMSGIYWGTTALDIMGQLERLERKSIIEFVKRCQCPNTGGFAPCEGHDPHLLYTLSAIQILCTYDALEEIDREAVVRFVVGLQQPDGSFFGDKWGEVDTRFSFCAVASLTLLGRMEQTIDVEKAVKFVLSCCNQTDGGFGSKPGAESHAGLIYCCVGFFSLTHRLHLLDVDKLGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLTIMGRLHWISSEKLQQFILSCQDTETGGFSDRTGNMPDIFHTLFGIGGLSLLGHSGLKAINPTLCMPQYIIDRLGIKPQLLPRP", "length": 347, "header": "tr|Q9XZ68-1|Q9XZ68_DROME Isoform 1 of Geranylgeranyl transferase type-2 subunit beta OS=Drosophila melanogaster OX=7227 GN=RabGGTb PE=1 SV=1 CANONICAL=Q9XZ68-1" }, "isoforms": [ { "isoform_ac": "Q9XZ68-1", "url": "https://www.uniprot.org/uniprotkb/Q9XZ68/entry#Q9XZ68-1", "sequence": { "sequence": "MDFTTFVKPSNGGGDSGGGGDADGGGQKLQFWKHVEYIENHGKQEDDYEYCMTEFLRMSGIYWGTTALDIMGQLERLERKSIIEFVKRCQCPNTGGFAPCEGHDPHLLYTLSAIQILCTYDALEEIDREAVVRFVVGLQQPDGSFFGDKWGEVDTRFSFCAVASLTLLGRMEQTIDVEKAVKFVLSCCNQTDGGFGSKPGAESHAGLIYCCVGFFSLTHRLHLLDVDKLGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLTIMGRLHWISSEKLQQFILSCQDTETGGFSDRTGNMPDIFHTLFGIGGLSLLGHSGLKAINPTLCMPQYIIDRLGIKPQLLPRP", "length": 347, "header": "tr|Q9XZ68-1|Q9XZ68_DROME Isoform 1 of Geranylgeranyl transferase type-2 subunit beta OS=Drosophila melanogaster OX=7227 GN=RabGGTb PE=1 SV=1 CANONICAL=Q9XZ68-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9XZ68", "url": "https://www.uniprot.org/uniprotkb/Q9XZ68" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9XZ68", "url": "https://www.uniprot.org/uniprotkb/Q9XZ68" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9XZ68", "url": "https://www.uniprot.org/uniprotkb/Q9XZ68" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9XZ68", "url": "https://www.uniprot.org/uniprotkb/Q9XZ68" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9XZ68", "url": "https://www.uniprot.org/uniprotkb/Q9XZ68" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9XZ68", "url": "https://www.uniprot.org/uniprotkb/Q9XZ68" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9XZ68", "url": "https://www.uniprot.org/uniprotkb/Q9XZ68" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9XZ68", "url": "https://www.uniprot.org/uniprotkb/Q9XZ68" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9XZ68", "url": "https://www.uniprot.org/uniprotkb/Q9XZ68" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9XZ68", "url": "https://www.uniprot.org/uniprotkb/Q9XZ68" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9XZ68", "url": "https://www.uniprot.org/uniprotkb/Q9XZ68" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG18627", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG18627", "resource": "KEGG Pathway" }, { "id": "R-DME-6803205", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6803205", "resource": "Reactome", "description": "TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain" }, { "id": "R-DME-8873719", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8873719", "resource": "Reactome", "description": "RAB geranylgeranylation" } ], "orthologs": [ { "uniprot_canonical_ac": "B0G172-1", "protein_name": "Probable geranylgeranyl transferase type-2 subunit beta", "gene_name": "rabggtb", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTDNINKESTTTTTTIDHTTNLLIDKHVEYIVKLGSKKDSFEYWVTEHIRMNGMYWGLSSLYLLKSLDKLDKNEVIQWLLSCQKSNGGFGGNTSHDDHLLSTLSAVQILIQYDALDKIDINSVVDYVVKLQREDGSFVGDQWGEVDTRFSYAAIMCLSLLKSLDKINCEKAVEYILSCQNFDGGFGSIPGAESHAGQIFTCVGALSILNEINKIDIDKLGWWLSERQLPNGGLNGRPEKSSDVCYSWWVLSALSAIDRLHWIDNDKLKSYILKCQDNETGGIADKPGDIPDVFHTFFGICGLSLMGYFKDQIESIDPVYALGTKTLQKLGLNLPWNKNL", "length": 339 }, "evidence": [ { "id": "Q9XZ68", "url": "https://omabrowser.org/oma/group/Q9XZ68/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "F1P4E5-1", "protein_name": "Geranylgeranyl transferase type-2 subunit beta", "gene_name": "RABGGTB", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGTPQKDVVIKPDAPSTLLSEKHADYIASYGTKKDDYEYCMSEYLRMSGVYWGLTAMDLMGQLHRMNKEEILAFIKSCQHECGGISASIGHDPHLLYTLSAVQILILYESLHVVDVNKIVEYVQSLQKEDGSFAGDKWGEIDTRFSFCAAATLALLGKLDAIDVGKAVEFVLSCMNFDGGFGCRPGSESHAGQIYCCTGFLAITDQLHQINVDLLGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLKMIGRLHWIDREKLRCFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSLLGEEQIKAVNPVFCMPEDVLQRINVQPELVS", "length": 331 }, "evidence": [ { "id": "Q9XZ68", "url": "https://omabrowser.org/oma/group/Q9XZ68/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "I3L5Z8-1", "protein_name": "MutS protein homolog 4", "gene_name": "MSH4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLRPESSPASLPVPGDSSLSVEVRPQVPRCSLGLQETPQSGPSAQAASVSSRPDTSGAAGDRSSSSSCPRAPSALPAQGSYCKSKRSYAENTFASDFTLGTSSSSARGSTCPQIVKTPLSAGNHQRSGYKSWTPQMEYSATSSSAVSAHSPSVVVAVVEGRGLARGEIGMASIDLKSPQIILSQFADNTTYAKVITKLKILSPLEIIMSNTACVVGNSTKLFTLITENFKNVNFTTIQRKYFNETKGLEYIEQLCTAEFSTVLMEVQSYYCLAAVAALLKYIEFIQNSLYAPKSLKICFQGSEQTAMIDSSSAQNLELLINNQDSRNNHTLFGVLNYTKTPGGSRRLRSNILEPLVDIETINMRLDCVQELLQDEELFFGLQSVIARFLDTEQLLSVLVQIPKQDTVNAAESKITNLIYLKHTLELVDPLKITLKNCNTPLLRAYYGSLEDKRFGIILDKIKTVINDDARYMKGCLNMRTQKCYAVRSNINEFLDIARRTYTEIVDDIAGMISQLAEKYSLPLRTSFSSARGFFIQMTTDCTALFNDKLPSEFIKISKVKNSYSFTSTDLIKMNERCQESLREIYHMTYMIVCKLLSEIYEHIHCLYKLSDTVSMLDMLLSFAHACTLSDYVRPEFTDTLAIKQGWHPILEKISVEKPVANNTYITEGSNFVIITGPNMSGKSTYLKQIALCQIMAQIGSYVPAEYSSFRIAEQIFTRISTDDDIETNSSTFMKEMKEIAYILHNANDKSLILIDELGRGTNTEEGIGICYAVCEYLLSLKAFTLFATHFLELCHIDVLYPNVENMYFEVQHVKNTSRNKEAILYTYKLSKGLTEEKNYGLKAAEASSLPPSIVLDAKEITTQITRQILQNQRSTPEMERQRAVYHLATRLVQTARNSQLDPDSLRTYLSNLKRKYEADFPRAEQVSGKTEE", "length": 932 }, "evidence": [ { "id": "Q9XZ68", "url": "https://omabrowser.org/oma/group/Q9XZ68/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P20133-1", "protein_name": "Geranylgeranyl transferase type-2 subunit beta", "gene_name": "BET2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSGSLTLLKEKHIRYIESLDTKKHNFEYWLTEHLRLNGIYWGLTALCVLDSPETFVKEEVISFVLSCWDDKYGAFAPFPRHDAHLLTTLSAVQILATYDALDVLGKDRKVRLISFIRGNQLEDGSFQGDRFGEVDTRFVYTALSALSILGELTSEVVDPAVDFVLKCYNFDGGFGLCPNAESHAAQAFTCLGALAIANKLDMLSDDQLEEIGWWLCERQLPEGGLNGRPSKLPDVCYSWWVLSSLAIIGRLDWINYEKLTEFILKCQDEKKGGISDRPENEVDVFHTVFGVAGLSLMGYDNLVPIDPIYCMPKSVTSKFKKYPYK", "length": 325 }, "evidence": [ { "id": "RGD:3530", "url": "https://alliancegenome.org/gene/RGD:3530#orthology", "database": "AGR" }, { "id": "MGI:99537", "url": "https://alliancegenome.org/gene/MGI:99537#orthology", "database": "AGR" }, { "id": "HGNC:9796", "url": "https://alliancegenome.org/gene/HGNC:9796#orthology", "database": "AGR" }, { "id": "FB:FBgn0028970", "url": "https://alliancegenome.org/gene/FB:FBgn0028970#orthology", "database": "AGR" }, { "id": "SGD:S000006380", "url": "https://alliancegenome.org/gene/SGD:S000006380#orthology", "database": "AGR" }, { "id": "Q9XZ68", "url": "https://omabrowser.org/oma/group/Q9XZ68/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P53611-1", "protein_name": "Geranylgeranyl transferase type-2 subunit beta", "gene_name": "RABGGTB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGTPQKDVIIKSDAPDTLLLEKHADYIASYGSKKDDYEYCMSEYLRMSGIYWGLTVMDLMGQLHRMNREEILAFIKSCQHECGGISASIGHDPHLLYTLSAVQILTLYDSINVIDVNKVVEYVKGLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLDAINVEKAIEFVLSCMNFDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVNSDLLGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLKIIGRLHWIDREKLRNFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSLLGEEQIKPVNPVFCMPEEVLQRVNVQPELVS", "length": 331 }, "evidence": [ { "id": "RGD:3530", "url": "https://alliancegenome.org/gene/RGD:3530#orthology", "database": "AGR" }, { "id": "MGI:99537", "url": "https://alliancegenome.org/gene/MGI:99537#orthology", "database": "AGR" }, { "id": "HGNC:9796", "url": "https://alliancegenome.org/gene/HGNC:9796#orthology", "database": "AGR" }, { "id": "FB:FBgn0028970", "url": "https://alliancegenome.org/gene/FB:FBgn0028970#orthology", "database": "AGR" }, { "id": "SGD:S000006380", "url": "https://alliancegenome.org/gene/SGD:S000006380#orthology", "database": "AGR" }, { "id": "Q9XZ68", "url": "https://omabrowser.org/oma/group/Q9XZ68/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P53612-1", "protein_name": "Geranylgeranyl transferase type-2 subunit beta", "gene_name": "Rabggtb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSLLFSWKGTQQKDVTIKSDAPDTLLLEKHADYIASYGSKKDDYEYCMSEYLRMSGVYWGLTVMDLMGQLHRMNREEILVFIKSCQHECGGISASIGHDPHLLYTLSAVQILTLYDSVHVINVDKVVAYVQSLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLDAINVEKAIEFVLSCMNFDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVNSDLLGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLKIIGRLHWIDREKLRSFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSLLGEEQIKPVSPVFCMPEEVLQRVNVQPELVS", "length": 339 }, "evidence": [ { "id": "RGD:3530", "url": "https://alliancegenome.org/gene/RGD:3530#orthology", "database": "AGR" }, { "id": "MGI:99537", "url": "https://alliancegenome.org/gene/MGI:99537#orthology", "database": "AGR" }, { "id": "HGNC:9796", "url": "https://alliancegenome.org/gene/HGNC:9796#orthology", "database": "AGR" }, { "id": "FB:FBgn0028970", "url": "https://alliancegenome.org/gene/FB:FBgn0028970#orthology", "database": "AGR" }, { "id": "SGD:S000006380", "url": "https://alliancegenome.org/gene/SGD:S000006380#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q08603-1", "protein_name": "Geranylgeranyl transferase type-2 subunit beta", "gene_name": "Rabggtb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGTQQKDVTIKSDAPDTLLLEKHADYIASYGSKKDDYEYCMSEYLRMSGVYWGLTVMDLMGQLHRMNKEEILVFIKSCQHECGGVSASIGHDPHLLYTLSAVQILTLYDSIHVINVDKVVAYVQSLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLDAINVEKAIEFVLSCMNFDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVNSDLLGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLKIIGRLHWIDREKLRSFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSLLGEEQIKPVSPVFCMPEEVLQRVNVQPELVS", "length": 331 }, "evidence": [ { "id": "RGD:3530", "url": "https://alliancegenome.org/gene/RGD:3530#orthology", "database": "AGR" }, { "id": "MGI:99537", "url": "https://alliancegenome.org/gene/MGI:99537#orthology", "database": "AGR" }, { "id": "HGNC:9796", "url": "https://alliancegenome.org/gene/HGNC:9796#orthology", "database": "AGR" }, { "id": "FB:FBgn0028970", "url": "https://alliancegenome.org/gene/FB:FBgn0028970#orthology", "database": "AGR" }, { "id": "SGD:S000006380", "url": "https://alliancegenome.org/gene/SGD:S000006380#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5E9B3-1", "protein_name": "Geranylgeranyl transferase type-2 subunit beta", "gene_name": "RABGGTB", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGTPQKDVIIKSDAPDTLLLEKHADYIASYGSKKDDYEYCMSEYLRMSGIYWGLTVMDLMGQLHRMNREEILTFIKSCQHECGGISASIGHDPHLLYTLSAVQILTLYDSINVIDINKVVEYVQSLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLDAINVEKAIEFVLSCMNFDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVNSDLLGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLKIIGRLHWIDREKLRSFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSLLGEEQIKPVSPVFCMPEEVLRRVNVQPELVS", "length": 331 }, "evidence": [ { "id": "Q9XZ68", "url": "https://omabrowser.org/oma/group/Q9XZ68/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q84J75-1", "protein_name": "Geranylgeranyl transferase type-2 subunit beta 1", "gene_name": "RGTB1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSTSSSQMVQLVADKHVRYILMAEKKKESFESVVMDHLRMNGAYWGLTTLDLLDKLGCVSEEEVISWLMTCQHESGGFAGNTGHDPHILYTLSAVQILALFDKINILDIGKVSSYVAKLQNEDGSFSGDMWGEIDTRFSYIAICCLSILKCLDKINVEKAVKYIVSCKNLDGGFGCTPGAESHAGQIFCCVGALAITGSLHHVDKDSLGWWLCERQLKAGGLNGRPEKLADVCYSWWVLSSLIMIDRVHWIDKAKLVKFILDCQDLDNGGISDRPEDAVDIFHTYFGVAGLSLLEYPGVKVIDPAYALPVDVVNRIIFTK", "length": 321 }, "evidence": [ { "id": "Q9XZ68", "url": "https://omabrowser.org/oma/group/Q9XZ68/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "Rab geranylgeranyltransferase activity", "id": "GO:0004663", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004663", "evidence": [ { "database": "UniProtKB", "id": "Q9XZ68", "url": "https://www.uniprot.org/uniprotkb/Q9XZ68" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q9XZ68", "url": "https://www.uniprot.org/uniprotkb/Q9XZ68" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "Q9XZ68", "url": "https://www.uniprot.org/uniprotkb/Q9XZ68" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Rab-protein geranylgeranyltransferase complex", "id": "GO:0005968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005968", "evidence": [ { "database": "UniProtKB", "id": "Q9XZ68", "url": "https://www.uniprot.org/uniprotkb/Q9XZ68" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 189, "end_pos": 191, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "21240", "name": "", "equation": "geranylgeranyl diphosphate + L-cysteinyl-[protein] = S-geranylgeranyl-L-cysteinyl-[protein] + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VN77-1", "Q9XZ68-1", "Q24173-1" ], "evidence": [ { "id": "21240", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/21240" } ] }, { "id": "R-DME-6801101", "name": "RABGGTA binds RABGGTB", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VN77-1", "Q9XZ68-1" ], "evidence": [ { "id": "R-DME-6801101", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6801101" } ] }, { "id": "R-DME-6801109", "name": "CHM binds RGGT", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VN77-1", "Q9XZ68-1" ], "evidence": [ { "id": "R-DME-6801109", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6801109" } ] }, { "id": "R-DME-8870457", "name": "FarC-PTP4A2 binds RABGGTB", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O61722-1", "Q9XZ68-1" ], "evidence": [ { "id": "R-DME-8870457", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8870457" } ] }, { "id": "R-DME-8870461", "name": "RABGGTA and RABGGTB bind", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O61722-1", "Q9VN77-1", "Q9XZ68-1" ], "evidence": [ { "id": "R-DME-8870461", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8870461" } ] }, { "id": "R-DME-8870465", "name": "RGGT binds the RAB-binding subunit", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q9VN77-1", "Q9XZ68-1" ], "evidence": [ { "id": "R-DME-8870465", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8870465" } ] }, { "id": "R-DME-8870466", "name": "RGGT:CHM binds RABs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O18333-1", "Q86BK8-1", "Q9VNG6-1", "Q9VN77-1", "Q9V3I2-1", "Q9W0A7-1", "O18339-1", "Q9VM50-1", "Q9VIW6-1", "O76742-1", "Q9XZ68-1" ], "evidence": [ { "id": "R-DME-8870466", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8870466" } ] }, { "id": "R-DME-8870469", "name": "RGGT geranylgeranylates RAB proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-1131164" ], "output_participant_list": [], "enzyme_list": [ "O18333-1", "Q86BK8-1", "Q9VNG6-1", "Q9VN77-1", "Q9V3I2-1", "Q9W0A7-1", "O18339-1", "Q9VM50-1", "Q9VIW6-1", "O76742-1", "Q9XZ68-1" ], "evidence": [ { "id": "R-DME-8870469", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8870469" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-1131164", "participant_name": "geranylgeranyl diphosphate [cytosol]", "crossref": [ { "id": "48861", "database": "ChEBI", "url": "" }, { "id": "C00353", "database": "COMPOUND", "url": "" }, { "id": "3052", "database": "Guide to Pharmacology - Ligands", "url": "" }, { "id": "ZINC000012495043", "database": "ZINC", "url": "" }, { "id": "HMDB0004486", "database": "HMDB Metabolite", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "O18333", "gene_name": "Rab2", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "O18333", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O18333" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "O18333", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O18333" } ] } ] }, { "uniprot_ac": "O18339", "gene_name": "Rab19", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "O18339", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O18339" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "O18339", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O18339" } ] } ] }, { "uniprot_ac": "O61722", "gene_name": "PRL-1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "O61722", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O61722" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "O61722", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O61722" } ] } ] }, { "uniprot_ac": "O76742", "gene_name": "Rab7", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "O76742", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O76742" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "O76742", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O76742" } ] } ] }, { "uniprot_ac": "Q24173", "gene_name": "betaggt-I", "activity": [ { "ec_number": "2.5.1.59", "activity": "geranylgeranyl diphosphate + L-cysteinyl-[protein] = S-geranylgeranyl-L-cysteinyl-[protein] + diphosphate.", "evidence": [ { "id": "Q24173", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q24173" } ] }, { "ec_number": "2.5.1.59", "activity": "", "evidence": [ { "id": "Q24173", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q24173" } ] } ] }, { "uniprot_ac": "Q86BK8", "gene_name": "Rab14", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "Q86BK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q86BK8" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "Q86BK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q86BK8" } ] } ] }, { "uniprot_ac": "Q9V3I2", "gene_name": "Rab5", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "Q9V3I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9V3I2" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "Q9V3I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9V3I2" } ] } ] }, { "uniprot_ac": "Q9VIW6", "gene_name": "Rab9", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "Q9VIW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VIW6" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "Q9VIW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VIW6" } ] } ] }, { "uniprot_ac": "Q9VM50", "gene_name": "Rab30", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "Q9VM50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VM50" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "Q9VM50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VM50" } ] } ] }, { "uniprot_ac": "Q9VN77", "gene_name": "RabGGTa", "activity": [ { "ec_number": "2.5.1.60", "activity": "geranylgeranyl diphosphate + L-cysteinyl-[protein] = S-geranylgeranyl-L-cysteinyl-[protein] + diphosphate.", "evidence": [ { "id": "Q9VN77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VN77" } ] }, { "ec_number": "2.5.1.60", "activity": "", "evidence": [ { "id": "Q9VN77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VN77" } ] } ] }, { "uniprot_ac": "Q9VNG6", "gene_name": "Rab23", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "Q9VNG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VNG6" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "Q9VNG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9VNG6" } ] } ] }, { "uniprot_ac": "Q9W0A7", "gene_name": "RabX5", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "Q9W0A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W0A7" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "Q9W0A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9W0A7" } ] } ] }, { "uniprot_ac": "Q9XZ68", "gene_name": "RabGGTb", "activity": [ { "ec_number": "2.5.1.60", "activity": "geranylgeranyl diphosphate + L-cysteinyl-[protein] = S-geranylgeranyl-L-cysteinyl-[protein] + diphosphate.", "evidence": [ { "id": "Q9XZ68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9XZ68" } ] }, { "ec_number": "2.5.1.60", "activity": "", "evidence": [ { "id": "Q9XZ68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9XZ68" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9XZ68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9XZ68" }, { "id": "PF00432", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00432" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Prenyltransferase alpha-alpha toroid", "eco_id": "ECO_0000259", "start_pos": 32, "end_pos": 329, "start_aa": "Trp", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.5.1.60", "ec_name": "geranylgeranyl diphosphate + L-cysteinyl-[protein] = S-geranylgeranyl-L-cysteinyl-[protein] + diphosphate.", "evidence": [ { "id": "2.5.1.60", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.5.1.60" }, { "id": "2.5.1.60", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.5.1.60" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 189, "end_pos": 191 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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"https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, 13", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, type 13", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "HPC13", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "HPC11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "HPC14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "prostate cancer, hereditary, 15", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "HPC15", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "prostate cancer, hereditary, 15", "description": "" }, { "id": "MONDO:0700275", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0700275", "name": "prostate cancer, hereditary", "description": "An instance of prostate cancer that is caused by an inherited genomic modification in an individual. Familial prostate cancer (FPC) is a malignant tumor of the prostate with an early onset. FPC is either asymptomatic or causes mictionary symptoms, erectile dysfunction, bone pain, venous compression and infectious or inflammatory syndrome (for the metastatic forms). It is also characterized by familial antecedents." }, { "id": "MIM:601518", "resource": "MIM", "url": "https://www.omim.org/entry/601518", "name": "Prostate cancer, hereditary, 1", "description": "Prostate cancer, hereditary, 1" }, { "id": "MIM:610997", "resource": "MIM", "url": "https://www.omim.org/entry/610997", "name": "Prostate cancer, hereditary, 9", "description": "Prostate cancer, hereditary, 9" }, { "id": "MIM:611868", "resource": "MIM", "url": "https://www.omim.org/entry/611868", "name": "Prostate cancer, hereditary, 12", "description": "Prostate cancer, hereditary, 12" }, { "id": "MIM:611928", "resource": "MIM", "url": "https://www.omim.org/entry/611928", "name": "Prostate cancer, hereditary, 13", "description": "Prostate cancer, hereditary, 13" }, { "id": "MIM:611955", "resource": "MIM", "url": "https://www.omim.org/entry/611955", "name": "Prostate cancer, hereditary, 11", "description": "Prostate cancer, hereditary, 11" }, { "id": "MIM:176807", "resource": "MIM", "url": "https://www.omim.org/entry/176807", "name": "Prostate cancer", "description": "Prostate cancer" } ], "unlinked_id_list": [], "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ] }, { "disease_id": "DOID:10534", "recommended_name": { "id": "DOID:10534", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach." }, "synonyms": [ { "id": "DOID:10534", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10534", "name": "gastric cancer", "description": "" }, { "id": "DOID:10534", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10534", "name": "gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer", "description": "A primary or metastatic malignant neoplasm involving the stomach." }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "Ca lesser curvature - stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "GC", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "cancer of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer risk after h. pylori infection", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer, somatic", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric tumor", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric tumour", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant stomach neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of body of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of greater curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of body of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of greater curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "stomach cancer", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "Ca body - stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "ca greater curvature of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of body of stomach", "description": "" }, { "id": "MIM:613659", "resource": "MIM", "url": "https://www.omim.org/entry/613659", "name": "Gastric cancer", "description": "Gastric cancer" } ], "unlinked_id_list": [], "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ] }, { "disease_id": "DOID:10763", "recommended_name": { "id": "DOID:10763", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries." }, "synonyms": [ { "id": "DOID:10763", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10763", "name": "HTN", "description": "" }, { "id": "DOID:10763", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10763", "name": "hyperpiesia", "description": "" }, { "id": "DOID:10763", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10763", "name": "vascular hypertensive disorder", "description": "" } ], "unlinked_id_list": [ "DOID:13731", "DOID:11130" ], "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ] }, { "disease_id": "DOID:11054", "recommended_name": { "id": "DOID:11054", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder." }, "synonyms": [ { "id": "DOID:11054", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11054", "name": "bladder cancer", "description": "" }, { "id": "DOID:11054", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11054", "name": "tumor of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder cancer", "description": "A primary or metastatic malignant neoplasm involving the bladder." }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "tumor of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "tumour of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "bladder cancer, somatic", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "cancer of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant bladder neoplasm", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant bladder tumor", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant bladder tumour", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of the urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm, bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm, urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of the urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor, urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumour of bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumour of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumour of the urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumour of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant urinary bladder neoplasm", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant urinary bladder tumor", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant urinary bladder tumour", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder cancer", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder malignant neoplasm", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder malignant tumor", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder malignant tumour", "description": "" }, { "id": "MIM:109800", "resource": "MIM", "url": "https://www.omim.org/entry/109800", "name": "Bladder cancer", "description": "Bladder cancer" } ], "unlinked_id_list": [], "evidence": [ { "id": "11054", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11054" } ] }, { "disease_id": "DOID:11088", "recommended_name": { "id": "DOID:11088", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11088", "name": "asphyxia neonatorum", "description": "A respiratory system disease that is characterized by deprivation of oxygen to a newborn infant that lasts long enough during the birth process to cause physical harm, usually to the brain." }, "synonyms": [ { "id": "DOID:11088", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11088", "name": "Asphyxia - birth", "description": "" }, { "id": "DOID:11088", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11088", "name": "Asphyxia, in liveborn infant", "description": "" }, { "id": "DOID:11088", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11088", "name": "Birth asphyxia", "description": "" }, { "id": "DOID:11088", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11088", "name": "postnatal asphyxia", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "11088", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11088" } ] }, { "disease_id": "DOID:12549", "recommended_name": { "id": "DOID:12549", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12549", "name": "hepatitis A", "description": "A viral hepatitis that results_in inflammation located_in liver, has_material_basis_in Hepatitis A virus (Hepatovirus ahepa), which is transmitted_by ingestion of contaminated food or water, or transmitted_by direct contact with an infected person. The infection has_symptom fever, has_symptom fatigue, has_symptom loss of appetite, has_symptom nausea, has_symptom vomiting, has_symptom abdominal pain, has_symptom clay-colored bowel movements, has_symptom joint pain, and has_symptom jaundice." }, "synonyms": [ { "id": "DOID:12549", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12549", "name": "Viral hepatitis, type A", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "12549", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12549" } ] }, { "disease_id": "DOID:127", "recommended_name": { "id": "DOID:127", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:127", "name": "leiomyoma", "description": "A cell type benign neoplasm that is a benign tumor of smooth muscle cells." }, "synonyms": [ { "id": "DOID:127", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:127", "name": "leiomyomatous neoplasm", "description": "" }, { "id": "DOID:127", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:127", "name": "leiomyomatous tumor", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "127", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:127" } ] }, { "disease_id": "DOID:1324", "recommended_name": { "id": "DOID:1324", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung." }, "synonyms": [ { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer", "description": "A malignant neoplasm involving the lung." }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "adenocarcinoma of lung, response to tyrosine kinase inhibitor in, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "adenocarcinoma of lung, somatic", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "cancer of lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer, protection against, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer, resistance to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer, somatic", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant lung neoplasm", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant lung tumor", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant lung tumour", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant neoplasm of lung", "description": "" }, { "id": "MONDO:0008903", 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"https://disease-ontology.org/term/DOID:3070", "name": "glioma, malignant", "description": "" }, { "id": "DOID:3070", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3070", "name": "malignant Neuroglial tumor", "description": "" }, { "id": "DOID:3070", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3070", "name": "malignant glioma", "description": "" }, { "id": "MONDO:0024498", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024498", "name": "glioma susceptibility 1", "description": "" }, { "id": "MONDO:0024498", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024498", "name": "GLM1", "description": "" }, { "id": "MONDO:0024498", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024498", "name": "glioblastoma, somatic", "description": "" }, { "id": "MONDO:0024498", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024498", "name": "glioma susceptibility 1", "description": "" }, { "id": "MONDO:0024498", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024498", "name": "glioma susceptibility 1, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0024498", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024498", "name": "glioma, susceptibility to, somatic", "description": "" }, { "id": "MIM:137800", "resource": "MIM", "url": "https://www.omim.org/entry/137800", "name": "Glioma 1", "description": "Glioma 1" } ], "unlinked_id_list": [ "DOID:0080879" ], "evidence": [ { "id": "3070", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3070" } ] }, { "disease_id": "DOID:3121", "recommended_name": { "id": "DOID:3121", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3121", "name": "gallbladder cancer", "description": "A biliary tract cancer that is located_in the gallbladder." }, "synonyms": [ { "id": "DOID:3121", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3121", "name": "gallbladder Ca", "description": "" }, { "id": "DOID:3121", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3121", "name": "gallbladder neoplasm", "description": "" }, { "id": "DOID:3121", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3121", "name": "localized malignant gallbladder neoplasm", "description": "" }, { "id": "DOID:3121", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3121", "name": "malignant neoplasm of gallbladder", "description": "" }, { "id": "DOID:3121", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3121", "name": "malignant tumor of the gallbladder", "description": "" }, { "id": "DOID:3121", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3121", "name": "malignant tumour of gallbladder", "description": "" }, { "id": "DOID:3121", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3121", "name": "tumor of the gallbladder", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "3121", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3121" } ] }, { "disease_id": "DOID:3393", "recommended_name": { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "coronary artery disease", "description": "An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles." }, "synonyms": [ { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "CHD", "description": "" }, { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "Coronary disease", "description": "" }, { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "coronary arteriosclerosis", "description": "" }, { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "coronary heart disease", "description": "" }, { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "Ischemic Heart Disease", "description": "" }, { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "myocardial ischemia", "description": "" }, { "id": "MONDO:0010331", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010331", "name": "coronary heart disease, susceptibility to, 3", "description": "" }, { "id": "MONDO:0010331", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010331", "name": "coronary heart disease, susceptibility to, 3", "description": "" }, { "id": "MONDO:0010331", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010331", "name": "coronary heart disease, susceptibility to, type 3", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary heart disease, susceptibility to, 1", "description": "Any coronary artery disease in which the cause of the disease is a mutation in the CX3CR1 gene." }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "CX3CR1 coronary artery disease", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary artery disease caused by mutation in CX3CR1", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary artery disease, resistance to", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary heart disease, susceptibility to", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary heart disease, susceptibility to, 1", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary heart disease, susceptibility to, type 1", "description": "" }, { "id": "MONDO:0012009", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012009", "name": "coronary heart disease, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012009", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012009", "name": "coronary heart disease, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012009", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012009", "name": "coronary heart disease, susceptibility to, type 2", "description": "" }, { "id": "MONDO:0012010", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012010", "name": "coronary heart disease, susceptibility to, 4", "description": "" }, { "id": "MONDO:0012010", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012010", "name": "coronary heart disease, susceptibility to, 4", "description": "" }, { "id": "MONDO:0012010", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012010", "name": "coronary heart disease, susceptibility to, type 4", "description": "" }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "coronary artery disease, autosomal dominant, 1", "description": "Any coronary artery disease in which the cause of the disease is a mutation in the MEF2A gene." }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "MEF2A coronary artery disease", "description": "" }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "coronary artery disease caused by mutation in MEF2A", "description": "" }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "coronary artery disease, autosomal dominant, 1", "description": "" }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "coronary artery disease, autosomal dominant, type 1", "description": "" }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "ADCAD1", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "coronary artery disease, autosomal dominant 2", "description": "Any coronary artery disease in which the cause of the disease is a mutation in the LRP6 gene." }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "LRP6 coronary artery disease", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "coronary artery disease caused by mutation in LRP6", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "coronary artery disease, autosomal dominant 2", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "coronary artery disease, autosomal dominant type 2", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "coronary artery disease, autosomal dominant, 2", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "ADCAD2", "description": "" }, { "id": "MONDO:0012628", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012628", "name": "coronary heart disease, susceptibility to, 8", "description": "" }, { "id": "MONDO:0012628", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012628", "name": "CHDS8", "description": "" }, { "id": "MONDO:0012628", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012628", "name": "coronary heart disease, susceptibility to, 8", "description": "" }, { "id": "MONDO:0012788", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012788", "name": "coronary heart disease, susceptibility to, 9", "description": "" }, { "id": "MONDO:0012788", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012788", "name": "CHDS9", "description": "" }, { "id": "MONDO:0012788", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012788", "name": "coronary heart disease, susceptibility to, 9", "description": "" }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "hydatidiform mole, recurrent, 2", "description": "Any complete hydatidiform mole in which the cause of the disease is a mutation in the KHDC3L gene." }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "KHDC3L complete hydatidiform mole", "description": "" }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "complete hydatidiform mole caused by mutation in KHDC3L", "description": "" }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "hydatidiform Mole, recurrent, type 2", "description": "" }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "hydatidiform mole, recurrent, 2", "description": "" }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "HYDM2", "description": "" }, { "id": "MIM:608320", "resource": "MIM", "url": "https://www.omim.org/entry/608320", "name": "Coronary artery disease, autosomal dominant, 1", "description": "Coronary artery disease, autosomal dominant, 1" }, { "id": "MIM:610947", "resource": "MIM", "url": "https://www.omim.org/entry/610947", "name": "Coronary artery disease, autosomal dominant, 2", "description": "Coronary artery disease, autosomal dominant, 2" }, { "id": "MIM:614293", "resource": "MIM", "url": "https://www.omim.org/entry/614293", "name": "Hydatidiform mole, recurrent, 2", "description": "Hydatidiform mole, recurrent, 2" } ], "unlinked_id_list": [ "DOID:11840" ], "evidence": [ { "id": "3393", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3393" } ] }, { "disease_id": "DOID:3525", "recommended_name": { "id": "DOID:3525", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3525", "name": "middle cerebral artery infarction", "description": "" }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "3525", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3525" } ] }, { "disease_id": "DOID:3565", "recommended_name": { "id": "DOID:3565", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3565", "name": "meningioma", "description": "A central nervous system cancer that are manifested in the central nervous system and arise from the arachnoid cap cells of the arachnoid villi in the meninges." }, "synonyms": [ { "id": "DOID:3565", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3565", "name": "meningeal neoplasm", "description": "" }, { "id": "DOID:3565", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3565", "name": "meningothelial cell tumor", "description": "" }, { "id": "DOID:3565", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3565", "name": "neoplasm of the meninges", "description": "" }, { "id": "DOID:3565", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3565", "name": "primary Meningeal tumor", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "3565", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3565" } ] }, { "disease_id": "DOID:3571", "recommended_name": { "id": "DOID:3571", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3571", "name": "liver cancer", "description": "A hepatobiliary system cancer that is located_in the liver." }, "synonyms": [ { "id": "DOID:3571", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3571", "name": "Ca liver - primary", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3571", "name": "Resectable malignant neoplasm of Liver", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3571", "name": "hepatic cancer", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3571", "name": "hepatic neoplasm", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3571", "name": "malignant hepato-biliary neoplasm", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3571", "name": "malignant neoplasm of liver", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3571", "name": "malignant neoplasm of liver, primary", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3571", "name": "malignant tumor of liver", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3571", "name": "neoplasm of liver", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3571", "name": "non-resectable primary hepatic malignant neoplasm", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3571", "name": "primary liver cancer", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3571", "name": "primary malignant neoplasm of liver", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3571", "name": "resectable malignant neoplasm of the liver", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3571", "name": "malignant neoplasm of liver, not specified as primary or secondary", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "3571", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3571" } ] }, { "disease_id": "DOID:3620", "recommended_name": { "id": "DOID:3620", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3620", "name": "central nervous system cancer", "description": "A nervous system cancer that is located_in the central nervous system." }, "synonyms": [ { "id": "DOID:3620", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3620", "name": "CNS neoplasm", "description": "" }, { "id": "DOID:3620", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3620", "name": "central nervous system tumor", "description": "" }, { "id": "DOID:3620", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3620", "name": "central nervous system tumors", "description": "" }, { "id": "DOID:3620", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3620", "name": "malignant neoplasm of central nervous system", "description": "" }, { "id": "DOID:3620", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3620", "name": "malignant tumor of CNS", "description": "" }, { "id": "DOID:3620", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3620", "name": "neoplasm of central nervous system", "description": "" } ], "unlinked_id_list": [ "DOID:4203", "DOID:3541", "DOID:3419", "DOID:4706", "DOID:1659", "DOID:368", "DOID:370", "DOID:2815", "DOID:5772" ], "evidence": [ { "id": "3620", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3620" } ] }, { "disease_id": "DOID:3748", "recommended_name": { "id": "DOID:3748", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3748", "name": "esophagus squamous cell carcinoma", "description": "An esophageal carcinoma that derives_from epithelial squamous cells located_in the esophagus." }, "synonyms": [ { "id": "DOID:3748", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3748", "name": "SCC of esophagus", "description": "" }, { "id": "DOID:3748", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3748", "name": "SCC of oesophagus", "description": "" }, { "id": "DOID:3748", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3748", "name": "oesophagus squamous cell carcinoma", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "3748", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3748" } ] }, { "disease_id": "DOID:3908", "recommended_name": { "id": "DOID:3908", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma." }, "synonyms": [ { "id": "DOID:3908", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3908", "name": "NSCLC", "description": "" }, { "id": "DOID:3908", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3908", "name": "Non-small cell lung cancer", "description": "" }, { "id": "DOID:3908", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3908", "name": "non-small cell lung carcinoma", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ] }, { "disease_id": "DOID:3910", "recommended_name": { "id": "DOID:3910", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3910", "name": "lung adenocarcinoma", "description": "A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin." }, "synonyms": [ { "id": "DOID:3910", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3910", "name": "bronchogenic lung adenocarcinoma", "description": "" }, { "id": "DOID:3910", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3910", "name": "nonsmall cell adenocarcinoma", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "3910", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3910" } ] }, { "disease_id": "DOID:3969", "recommended_name": { "id": "DOID:3969", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3969", "name": "papillary thyroid carcinoma", "description": "A differentiated thyroid gland carcinoma that is characterized by the small mushroom shape of the tumor which has a stem attached to the epithelial layer and arises from the follicular cells of the thyroid gland." }, "synonyms": [ { "id": "DOID:3969", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3969", "name": "Papillary carcinoma of the Thyroid gland", "description": "" }, { "id": "DOID:3969", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3969", "name": "thyroid gland papillary carcinoma", "description": "" }, { "id": "DOID:3969", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3969", 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"name": "malignant neoplasm of middle third of oesophagus", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "malignant neoplasm of proximal third of esophagus", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "malignant neoplasm of proximal third of oesophagus", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "malignant neoplasm of upper third esophagus", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "malignant neoplasm of upper third oesophagus", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "malignant tumor of abdominal esophagus", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "malignant tumor of distal third of esophagus", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "malignant tumor of proximal third of esophagus", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "malignant tumor of the middle third of the esophagus", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "malignant tumour of abdominal oesophagus", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "malignant tumour of distal third of oesophagus", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "malignant tumour of proximal third of oesophagus", "description": "" }, { "id": "MONDO:0007576", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007576", "name": "malignant tumour of the middle third of the oesophagus", "description": "" }, { "id": "MIM:133239", "resource": "MIM", "url": "https://www.omim.org/entry/133239", "name": "Esophageal cancer", "description": "Esophageal cancer" } ], "unlinked_id_list": [], "evidence": [ { "id": "5041", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5041" } ] }, { "disease_id": "DOID:5082", "recommended_name": { "id": "DOID:5082", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5082", "name": "liver cirrhosis", "description": "" }, "synonyms": [ { "id": "DOID:5082", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5082", "name": "Cirrhosis", "description": "" }, { "id": "DOID:5082", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5082", "name": "cirrhosis of liver", "description": "" }, { "id": "MONDO:0005155", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005155", "name": "cirrhosis of liver", "description": "A disorder characterized by replacement of the liver parenchyma with fibrous tissue and regenerative nodules. It is usually caused by alcoholism, hepatitis B, and hepatitis C. Complications include the development of ascites, esophageal varices, bleeding, and hepatic encephalopathy." }, { "id": "MONDO:0005155", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005155", "name": "cirrhosis", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "5082", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5082" } ] }, { "disease_id": "DOID:5517", "recommended_name": { "id": "DOID:5517", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5517", "name": "stomach carcinoma", "description": "A stomach cancer that is located_in the stomach." }, "synonyms": [ { "id": "DOID:5517", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5517", "name": "cancer of the stomach", "description": "" }, { "id": "DOID:5517", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5517", "name": "carcinoma of stomach", "description": "" }, { "id": "DOID:5517", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5517", "name": "gastric carcinoma", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "5517", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5517" } ] }, { "disease_id": "DOID:6270", "recommended_name": { "id": "DOID:6270", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:6270", "name": "gastric cardia carcinoma", "description": "" }, "synonyms": [ { "id": "DOID:6270", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:6270", "name": "carcinoma of Cardia of stomach", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "6270", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6270" } ] }, { "disease_id": "DOID:6271", "recommended_name": { "id": "DOID:6271", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:6271", "name": "gastric cardia adenocarcinoma", "description": "" }, "synonyms": [ { "id": "DOID:6271", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:6271", "name": "adenocarcinoma of Cardia of stomach", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "6271", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6271" } ] }, { "disease_id": "DOID:684", "recommended_name": { "id": "DOID:684", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver." }, "synonyms": [ { "id": "DOID:684", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:684", "name": "Hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma", "description": "A malignant tumor that arises from hepatocytes. Hepatocellular carcinoma is relatively rare in the United States but very common in all African countries south of the Sahara and in Southeast Asia. Most cases are seen in patients over the age of 50 years, but this tumor can also occur in younger individuals and even in children. Hepatocellular carcinoma is more common in males than females and is associated with hepatitis B, hepatitis C, chronic alcohol abuse and cirrhosis. Serum elevation of alpha-fetoprotein occurs in a large percentage of patients with hepatocellular carcinoma. Grossly, hepatocellular carcinoma may present as a single mass, as multiple nodules, or as diffuse liver involvement. Microscopically, there is a wide range of differentiation from tumor to tumor (well differentiated to poorly differentiated tumors). Hepatocellular carcinomas quickly metastasize to regional lymph nodes and lung. The overall median survival of untreated liver cell carcinoma is about 4 months. The most effective treatment of hepatocellular carcinoma is complete resection of the tumor. Lately, an increasing number of tumors have been treated with liver transplantation." }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "HCC", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "cancer, hepatocellular", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of liver", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of the liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma, hepatocellular, malignant", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatoblastoma, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular adenocarcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular cancer", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular cancer, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma, childhood type, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver cell cancer (hepatocellular carcinoma)", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver cell carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "primary carcinoma of liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "primary carcinoma of the liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "adult hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "adult primary hepatocellular carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma", "description": "A malignant tumor that arises from hepatocytes. Hepatocellular carcinoma is relatively rare in the United States but very common in all African countries south of the Sahara and in Southeast Asia. Most cases are seen in patients over the age of 50 years, but this tumor can also occur in younger individuals and even in children. Hepatocellular carcinoma is more common in males than females and is associated with hepatitis B, hepatitis C, chronic alcohol abuse and cirrhosis. Serum elevation of alpha-fetoprotein occurs in a large percentage of patients with hepatocellular carcinoma. Grossly, hepatocellular carcinoma may present as a single mass, as multiple nodules, or as diffuse liver involvement. Microscopically, there is a wide range of differentiation from tumor to tumor (well differentiated to poorly differentiated tumors). Hepatocellular carcinomas quickly metastasize to regional lymph nodes and lung. The overall median survival of untreated liver cell carcinoma is about 4 months. The most effective treatment of hepatocellular carcinoma is complete resection of the tumor. Lately, an increasing number of tumors have been treated with liver transplantation." }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "HCC", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "cancer, hepatocellular", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of liver", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of the liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma, hepatocellular, malignant", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatoblastoma, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular adenocarcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular cancer", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular cancer, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma, childhood type, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver cell cancer (hepatocellular carcinoma)", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver cell carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "primary carcinoma of liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "primary carcinoma of the liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "adult hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "adult primary hepatocellular carcinoma", "description": "" }, { "id": "MIM:114550", "resource": "MIM", "url": "https://www.omim.org/entry/114550", "name": "Hepatocellular carcinoma", "description": "Hepatocellular carcinoma" } ], "unlinked_id_list": [], "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ] }, { "disease_id": "DOID:8552", "recommended_name": { "id": "DOID:8552", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8552", "name": "chronic myeloid leukemia", "description": "A myeloid leukemia that is characterized by over production of white blood cells." }, "synonyms": [ { "id": "DOID:8552", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8552", "name": "CML", "description": "" }, { "id": "DOID:8552", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8552", "name": "CML - chronic Myelogenous Leukemia", "description": "" }, { "id": "DOID:8552", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8552", "name": "Myeloid Leukemia, chronic", "description": "" }, { "id": "DOID:8552", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8552", "name": "chronic granulocytic leukaemia", "description": "" }, { "id": "DOID:8552", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8552", "name": "chronic granulocytic leukemia", "description": "" }, { "id": "DOID:8552", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8552", "name": "chronic myelogenous leukaemia", "description": "" }, { "id": "DOID:8552", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8552", "name": "chronic myelogenous leukemia", "description": "" }, { "id": "DOID:8552", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8552", "name": "chronic myeloid leukaemia", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "chronic myeloid leukemia", "description": "A chronic myeloproliferative neoplasm characterized by the expression of the BCR-ABL1 fusion gene. It presents with neutrophilic leukocytosis. It can appear at any age, but it mostly affects middle aged and older individuals. Patients usually present with fatigue, weight loss, anemia, night sweats, and splenomegaly. If untreated, it follows a biphasic or triphasic natural course; an initial indolent chronic phase which is followed by an accelerated phase, a blast phase, or both. Allogeneic stem cell transplantation and tyrosine kinase inhibitors delay disease progression and prolong overall survival." }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "BCR-ABL Positive chronic myelogenous leukaemia", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "BCR-ABL Positive chronic myelogenous leukemia", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "CML", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "CML - chronic myelogenous leukaemia", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "CML - chronic myelogenous leukemia", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "chronic granulocytic leukemia", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "chronic myelocytic leukaemia", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "chronic myelocytic leukemia", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "chronic myelogenous leukaemia (CML)", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "chronic myelogenous leukemia", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "chronic myelogenous leukemia (CML)", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "chronic myelogenous leukemia, BCR-ABL1 Positive", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "chronic myelogenous leukemias", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "chronic myeloid leukemia", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "hematopoeitic - chronic myelocytic leukaemia (CML)", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "hematopoeitic - chronic myelocytic leukemia (CML)", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "leukimia, chronic myeloid", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "myeloid leukemia, chronic", "description": "" }, { "id": "MIM:608232", "resource": "MIM", "url": "https://www.omim.org/entry/608232", "name": "Leukemia, chronic myeloid, atypical", "description": "Leukemia, chronic myeloid, atypical" } ], "unlinked_id_list": [], "evidence": [ { "id": "8552", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8552" } ] }, { "disease_id": "DOID:8719", "recommended_name": { "id": "DOID:8719", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8719", "name": "in situ carcinoma", "description": "A carcinoma that is an early development defined by the absence of invasion of surrounding tissues." }, "synonyms": [], "unlinked_id_list": [ "DOID:9108" ], "evidence": [ { "id": "8719", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8719" } ] }, { "disease_id": "DOID:8947", "recommended_name": { "id": "DOID:8947", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8947", "name": "diabetic retinopathy", "description": "" }, "synonyms": [ { "id": "DOID:8947", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8947", "name": "Retinal abnormality - diabetes-related", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "8947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8947" } ] }, { "disease_id": "DOID:9256", "recommended_name": { "id": "DOID:9256", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum." }, "synonyms": [ { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer", "description": "A primary or metastatic malignant neoplasm that affects the colon or rectum. Representative examples include carcinoma, lymphoma, and sarcoma." }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "cancer of colorectum", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "cancer of large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "cancer of large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "cancer of the large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colon cancer, advanced, somatic", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colon cancer, somatic", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer with chromosomal instability, somatic", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer, somatic", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectum cancer", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant colorectal neoplasm", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant colorectal tumor", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant colorectal tumour", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant colorectum neoplasm", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large bowel neoplasm", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large bowel tumor", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large bowel tumour", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large intestine neoplasm", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large intestine tumor", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large intestine tumour", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of colorectum", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of the large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of the large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumor of large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumor of large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumor of the large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumor of the large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumour of large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumour of large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumour of the large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumour of the large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "CRC", "description": "" }, { "id": "MIM:114500", "resource": "MIM", "url": "https://www.omim.org/entry/114500", "name": "Colorectal cancer", "description": "Colorectal cancer" } ], "unlinked_id_list": [], "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ] }, { "disease_id": "DOID:9261", "recommended_name": { "id": "DOID:9261", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9261", "name": "nasopharynx carcinoma", "description": "A pharynx cancer that is located in the nasopharynx, the uppermost region of the pharynx or throat, where the nasal passages and auditory tubes join the remainder of the upper respiratory tract." }, "synonyms": [ { "id": "DOID:9261", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9261", "name": "Nasopharyngeal carcinoma", "description": "" }, { "id": "DOID:9261", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9261", "name": "malignant Nasopharyngeal tumor", "description": "" }, { "id": "DOID:9261", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9261", "name": "malignant neoplasm of nasopharynx", "description": "" }, { "id": "DOID:9261", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9261", "name": "nasopharynx cancer", "description": "" }, { "id": "MONDO:0008067", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008067", "name": "nasopharyngeal carcinoma, susceptibility to, 2", "description": "" }, { "id": "MONDO:0008067", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008067", "name": "nasopharyngeal carcinoma, susceptibility to, 2", "description": "" }, { "id": "MONDO:0008067", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008067", "name": "nasopharyngeal carcinoma, susceptibility to, type 2", "description": "" }, { "id": "MONDO:0008067", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008067", "name": "NPCA2", "description": "" }, { "id": "MONDO:0011775", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011775", "name": "nasopharyngeal carcinoma, susceptibility to, 1", "description": "Any nasopharyngeal carcinoma in which the cause of the disease is a mutation in the TP53 gene." }, { "id": "MONDO:0011775", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011775", "name": "TP53 nasopharyngeal carcinoma", "description": "" }, { "id": "MONDO:0011775", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011775", "name": "nasopharyngeal carcinoma 1", "description": "" }, { "id": "MONDO:0011775", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011775", "name": "nasopharyngeal carcinoma caused by mutation in TP53", "description": "" }, { "id": "MONDO:0011775", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011775", "name": "nasopharyngeal carcinoma, somatic", "description": "" }, { "id": "MONDO:0011775", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011775", "name": "nasopharyngeal carcinoma, susceptibility to, 1", "description": "" }, { "id": "MONDO:0011775", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011775", "name": "NPC", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "9261", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9261" } ] }, { "disease_id": "DOID:9352", "recommended_name": { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin." }, "synonyms": [ { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "NIDDM", "description": "" }, { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "non-insulin-dependent diabetes mellitus", "description": "" }, { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "type 2 diabetes", "description": "" }, { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "type II diabetes mellitus", "description": "" }, { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "insulin resistance", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type 2 diabetes mellitus", "description": "A type of diabetes mellitus that is characterized by insulin resistance or desensitization and increased blood glucose levels. This is a chronic disease that can develop gradually over the life of a patient and can be linked to both environmental factors and heredity." }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "NIDDM", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "T2D", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "T2DM", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "T2DM - type 2 diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "adult onset diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "adult-onset diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitis type 2", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitis type II", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent, association with", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent, late onset", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, type 2", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, type II", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes, type 2", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "insulin resistance, severe, digenic", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "non-insulin dependent diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "non-insulin dependent diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "noninsulin dependent diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "noninsulin-dependent diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type 2 diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type 2 diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type 2 diabetes mellitus non-insulin dependent", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type II diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type II diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent, 2", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "diabetes mellitus, noninsulin-dependent, 1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "diabetes mellitus, noninsulin-dependent 1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "diabetes mellitus, noninsulin-dependent, 1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "diabetes mellitus, noninsulin-dependent, type 1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "NIDDM1", "description": "" }, { "id": "MONDO:0011072", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011072", "name": "diabetes mellitus, noninsulin-dependent, 2", "description": "" }, { "id": "MONDO:0011072", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011072", "name": "NIDDM2", "description": "" }, { "id": "MONDO:0011072", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011072", "name": "diabetes mellitus, noninsulin-dependent, 2", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "diabetes mellitus, noninsulin-dependent, 3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "diabetes mellitus, noninsulin-dependent, 3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "diabetes mellitus, noninsulin-dependent, type 3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "type 2 diabetes mellitus 3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "NIDDM3", "description": "" }, { "id": "MONDO:0011955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011955", "name": "diabetes mellitus, noninsulin-dependent, 4", "description": "" }, { "id": "MONDO:0011955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011955", "name": "diabetes mellitus, noninsulin-dependent, 4", "description": "" }, { "id": "MONDO:0011955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011955", "name": "diabetes mellitus, noninsulin-dependent, type 4", "description": "" }, { "id": "MIM:125853", "resource": "MIM", "url": "https://www.omim.org/entry/125853", "name": "Type 2 diabetes mellitus", "description": "Type 2 diabetes mellitus" }, { "id": "MIM:601283", "resource": "MIM", "url": "https://www.omim.org/entry/601283", "name": "Type 2 diabetes mellitus 1", "description": "Type 2 diabetes mellitus 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ] }, { "disease_id": "DOID:9655", "recommended_name": { "id": "DOID:9655", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9655", "name": "oral mucosa leukoplakia", "description": "A mouth disease that is characterized by a white patch or plaque that develops in the oral cavity and is strongly associated with smoking." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "9655", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9655" } ] }, { "disease_id": "DOID:9669", "recommended_name": { "id": "DOID:9669", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9669", "name": "senile cataract", "description": "A cataract that is characterized by thickening and loss of transparency of the lens with age progression, caused by a multifactorial etiology related to aging." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "9669", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9669" } ] }, { "disease_id": "DOID:9952", "recommended_name": { "id": "DOID:9952", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9952", "name": "acute lymphoblastic leukemia", "description": "A acute leukemia that is characterized by over production of lymphoblasts." }, "synonyms": [ { "id": "DOID:9952", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9952", "name": "acute lymphoblastic leukaemia", "description": "" }, { "id": "DOID:9952", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9952", "name": "acute lymphocytic leukaemia", "description": "" }, { "id": "DOID:9952", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9952", "name": "ALL", "description": "" }, { "id": "DOID:9952", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9952", "name": "precursor lymphoblastic lymphoma/leukemia", "description": "" }, { "id": "MONDO:0009539", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009539", "name": "lymphoblastic leukemia, acute, with lymphomatous features", "description": "" }, { "id": "MONDO:0009539", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009539", "name": "leukemia, acute lymphoblastic", "description": "" }, { "id": "MONDO:0009539", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009539", "name": "lymphoblastic leukemia, acute, with lymphomatous features", "description": "" }, { "id": "MONDO:0009539", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009539", "name": "lall", "description": "" }, { "id": "MONDO:0013108", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013108", "name": "leukemia, acute lymphocytic, susceptibility to, 1", "description": "" }, { "id": "MONDO:0013108", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013108", "name": "T-cell acute lymphoblastic leukemia, somatic", "description": "" }, { "id": "MONDO:0013108", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013108", "name": "leukemia, T-cell acute lymphoblastic, somatic", "description": "" }, { "id": "MONDO:0013108", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013108", "name": "leukemia, T-cell acute lymphocytic, somatic", "description": "" }, { "id": "MONDO:0013108", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013108", "name": "leukemia, acute lymphoblastic, somatic", "description": "" }, { "id": "MONDO:0013108", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013108", "name": "leukemia, acute lymphocytic, Philadelphia chromosome positive, somatic", "description": "" }, { "id": "MONDO:0013108", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013108", "name": "leukemia, acute lymphocytic, susceptibility to, 1", "description": "" }, { "id": "MONDO:0013108", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013108", "name": "ALL", "description": "" }, { "id": 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"database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002706", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002706", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036420", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036420", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045080", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045080", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG4208", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG4208", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WIEKCYE", "url": "https://omabrowser.org/oma/group/WIEKCYE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9Y095", "url": "https://www.orthodb.org/?gene=Q9Y095", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11370", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11370", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11370:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11370:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00533", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00533", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01834", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01834", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-5685939", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-5685939", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-6782210", "url": 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"MPIALFKSVREVSSEDAVHVAANLLKENAGKKWRTKAPGEKSAYVVLEFEEPQQITGIDIGNEHAAFIEVLVSRTGCQADDFRELLLSSSFMTPIESKNSSNPNRVRCFSSTSLAESALPEKWKLLQIVCTQPFNRHVPYGLSFVKVHVVAAAAPKVKSLVPQGVMQFGTFKLREESPDSETDNQVNRFHSWKKQTQHKSPAISATSTAAAIRDAGSTALRRLSAGKVSSLAASPKTSTSPSPVLNALRSVSPTPLDAKPLDRNRASLLFGDDDEDVKDAEVNAKKQRLSKHLEADKDRRRLEQEKERESRKKKSSRHSLDKSISKEDKPPAKEHNSSSREKSTAKEEKEQLRKEERSHSKEEKSRRKEKSKHDHRSSDTSNSKESSRPTAQKRHSSPTAVAVTPAKKQKIVDTAIQYRPLNQLLKGVVLVISGIQNPDRADLRSKAVALGAKYKADWGSGCTHLICAFKNTPKYNQVKGKGKIVTRSWIEKCYELKKYLPWRRYALDTNDIGQPESDEELCDEATRPRRDSSKDDVAMLEDSKLTALADQNDVEMNPDALSGIDTEDELQRVAEENKTKKAKLRTTVKTKSQDIYEVSTDEEDYLELKKKQID", "length": 614, "header": "tr|Q9Y095-1|Q9Y095_DROME Isoform 1 of XRCC1 OS=Drosophila melanogaster OX=7227 GN=XRCC1 PE=1 SV=1 CANONICAL=Q9Y095-1" }, "isoforms": [ { "isoform_ac": "Q9Y095-1", "url": "https://www.uniprot.org/uniprotkb/Q9Y095/entry#Q9Y095-1", "sequence": { "sequence": "MPIALFKSVREVSSEDAVHVAANLLKENAGKKWRTKAPGEKSAYVVLEFEEPQQITGIDIGNEHAAFIEVLVSRTGCQADDFRELLLSSSFMTPIESKNSSNPNRVRCFSSTSLAESALPEKWKLLQIVCTQPFNRHVPYGLSFVKVHVVAAAAPKVKSLVPQGVMQFGTFKLREESPDSETDNQVNRFHSWKKQTQHKSPAISATSTAAAIRDAGSTALRRLSAGKVSSLAASPKTSTSPSPVLNALRSVSPTPLDAKPLDRNRASLLFGDDDEDVKDAEVNAKKQRLSKHLEADKDRRRLEQEKERESRKKKSSRHSLDKSISKEDKPPAKEHNSSSREKSTAKEEKEQLRKEERSHSKEEKSRRKEKSKHDHRSSDTSNSKESSRPTAQKRHSSPTAVAVTPAKKQKIVDTAIQYRPLNQLLKGVVLVISGIQNPDRADLRSKAVALGAKYKADWGSGCTHLICAFKNTPKYNQVKGKGKIVTRSWIEKCYELKKYLPWRRYALDTNDIGQPESDEELCDEATRPRRDSSKDDVAMLEDSKLTALADQNDVEMNPDALSGIDTEDELQRVAEENKTKKAKLRTTVKTKSQDIYEVSTDEEDYLELKKKQID", "length": 614, "header": "tr|Q9Y095-1|Q9Y095_DROME Isoform 1 of XRCC1 OS=Drosophila melanogaster OX=7227 GN=XRCC1 PE=1 SV=1 CANONICAL=Q9Y095-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 254, "start_aa": "Thr", "end_pos": 254, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr254", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 404, "start_aa": "Thr", "end_pos": 404, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr404", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9Y095", "url": "https://www.uniprot.org/uniprotkb/Q9Y095" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9Y095", "url": "https://www.uniprot.org/uniprotkb/Q9Y095" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9Y095", "url": "https://www.uniprot.org/uniprotkb/Q9Y095" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9Y095", "url": "https://www.uniprot.org/uniprotkb/Q9Y095" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9Y095", "url": "https://www.uniprot.org/uniprotkb/Q9Y095" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9Y095", "url": "https://www.uniprot.org/uniprotkb/Q9Y095" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9Y095", "url": "https://www.uniprot.org/uniprotkb/Q9Y095" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9Y095", "url": "https://www.uniprot.org/uniprotkb/Q9Y095" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9Y095", "url": "https://www.uniprot.org/uniprotkb/Q9Y095" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9Y095", "url": "https://www.uniprot.org/uniprotkb/Q9Y095" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9Y095", "url": "https://www.uniprot.org/uniprotkb/Q9Y095" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG4208", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG4208", "resource": "KEGG Pathway" }, { "id": "R-DME-5685939", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-5685939", "resource": "Reactome", "description": "HDR through MMEJ (alt-NHEJ)" }, { "id": "R-DME-6782210", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-6782210", "resource": "Reactome", "description": "Gap-filling DNA repair synthesis and ligation in TC-NER" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AC58HG74-1", "protein_name": "DNA repair protein XRCC1", "gene_name": "xrcc1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPELKLKHVVSCSSEDNTHKADNLLSSDTYRKWKAARPGEKQVSVILQLEKEEQIHSIDIGNEGSAFIEVLVGHSTSVKDQDFEVLLVTSSFMSPTESRNGTNTNRVRFFGPGQLVKAQSQEKWDRVKIVCSQPYSKTIAYGISFIKLHSPPDGNEAPVSTPPKLTKLGQFRVKDESPSAGSNVQPGALFFSRDTSAKSSTGLKVSPPNERLSYAAAALKTEGSSTHTPASDTQQAPVKRKFEFSKERLEASGPPAKKPSSSASAETTPKAKARSSMGTSPSSRASPAQKSSDKRESPKTKPESKPKPKPKPKSSESVPFNRILEGVVFVLSGFQNPFRADLRDKALALGARYRPDWTPDATHLICAFANTPKYSQVKAAGGIIVRKEWVMDCHKNKQKISCKRYLMDGAESSSESEAEQDESEDETPKVKTPEKKPVTPKKQQPVEEEEEEEEEEYGGSTDEEGPGDDGSGMDTEDELNRVEMASRKKKAAEQSADKGKNEDPYGGSTDENTDAEEEEDKPIPELPDFLKGKRFYLYGKFPDNQKRLLLRYIIAFNGAVEDYMSEKVQFVITSEGWDDSFEDALMENGSLSFVKPTWIFAINDRQKMLPYQPYTVVP", "length": 618 }, "evidence": [ { "id": "RGD:619823", "url": "https://alliancegenome.org/gene/RGD:619823#orthology", "database": "AGR" }, { "id": "HGNC:12828", "url": "https://alliancegenome.org/gene/HGNC:12828#orthology", "database": "AGR" }, { "id": "MGI:99137", "url": "https://alliancegenome.org/gene/MGI:99137#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040822-30", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040822-30#orthology", "database": "AGR" }, { "id": "FB:FBgn0026751", "url": "https://alliancegenome.org/gene/FB:FBgn0026751#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P18887-1", "protein_name": "DNA repair protein XRCC1", "gene_name": "XRCC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPEIRLRHVVSCSSQDSTHCAENLLKADTYRKWRAAKAGEKTISVVLQLEKEEQIHSVDIGNDGSAFVEVLVGSSAGGAGEQDYEVLLVTSSFMSPSESRSGSNPNRVRMFGPDKLVRAAAEKRWDRVKIVCSQPYSKDSPFGLSFVRFHSPPDKDEAEAPSQKVTVTKLGQFRVKEEDESANSLRPGALFFSRINKTSPVTASDPAGPSYAAATLQASSAASSASPVSRAIGSTSKPQESPKGKRKLDLNQEEKKTPSKPPAQLSPSVPKRPKLPAPTRTPATAPVPARAQGAVTGKPRGEGTEPRRPRAGPEELGKILQGVVVVLSGFQNPFRSELRDKALELGAKYRPDWTRDSTHLICAFANTPKYSQVLGLGGRIVRKEWVLDCHRMRRRLPSQRYLMAGPGSSSEEDEASHSGGSGDEAPKLPQKQPQTKTKPTQAAGPSSPQKPPTPEETKAASPVLQEDIDIEGVQSEGQDNGAEDSGDTEDELRRVAEQKEHRLPPGQEENGEDPYAGSTDENTDSEEHQEPPDLPVPELPDFFQGKHFFLYGEFPGDERRKLIRYVTAFNGELEDYMSDRVQFVITAQEWDPSFEEALMDNPSLAFVRPRWIYSCNEKQKLLPHQLYGVVPQA", "length": 633 }, "evidence": [ { "id": "RGD:619823", "url": "https://alliancegenome.org/gene/RGD:619823#orthology", "database": "AGR" }, { "id": "HGNC:12828", "url": "https://alliancegenome.org/gene/HGNC:12828#orthology", "database": "AGR" }, { "id": "MGI:99137", "url": "https://alliancegenome.org/gene/MGI:99137#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040822-30", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040822-30#orthology", "database": "AGR" }, { "id": "FB:FBgn0026751", "url": "https://alliancegenome.org/gene/FB:FBgn0026751#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q60596-1", "protein_name": "DNA repair protein XRCC1", "gene_name": "Xrcc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPEISLRHVVSCSSQDSTHCAENLLKADTYRKWRAAKAGEKTISVVLQLEKEEQIHSVDIGNDGSAFVEVLVGSSAGGATAGEQDYEVLLVTSSFMSPSESRSGSNPNRVRIFGPDKLVRAAAEKRWDRVKIVCSQPYSKDSPYGLSFVKFHSPPDKDEAEATSQKVTVTKLGQFRVKEEDDSANSLKPGALFFSRINKTSSASTSDPAGPSYAAATLQASSAASSASPVPKVVGSSSKPQEPPKGKRKLDLSLEDRKPPSKPSAGPSTLKRPKLSVPSRTPAAAPASTPAQRAVPGKPRGEGTEPRGARTGPQELGKILQGVVVVLSGFQNPFRSELRDKALELGAKYRPDWTPDSTHLICAFANTPKYSQVLGLGGRIVRKEWVLDCHHMRRRLPSRRYLMAGLGSSSEDEGDSHSESGEDEAPKLPQKRPQPKAKTQAAGPSSPPRPPTPKETKAPSPGPQDNSDTEGEESEGRDNGAEDSGDTEDELRRVAKQREQRQPPAPEENGEDPYAGSTDENTDSETPSEADLPIPELPDFFEGKHFFLYGEFPGDERRRLIRYVTAFNGELEDYMNERVQFVITAQEWDPNFEEALMENPSLAFVRPRWIYSCNEKQKLLPHQLYGVVPQA", "length": 631 }, "evidence": [ { "id": "RGD:619823", "url": "https://alliancegenome.org/gene/RGD:619823#orthology", "database": "AGR" }, { "id": "HGNC:12828", "url": "https://alliancegenome.org/gene/HGNC:12828#orthology", "database": "AGR" }, { "id": "MGI:99137", "url": "https://alliancegenome.org/gene/MGI:99137#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040822-30", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040822-30#orthology", "database": "AGR" }, { "id": "FB:FBgn0026751", "url": "https://alliancegenome.org/gene/FB:FBgn0026751#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9ESZ0-1", "protein_name": "DNA repair protein XRCC1", "gene_name": "Xrcc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEISLRHVVSCSSQDSTHRAENLLKADTYRKWRSAKAGEKTISVVLQLEKEEQIHSVDIGNDGSAFVEVLVGSSAGGATAGEQDYEVLLVTSSFMSPSESRSGSNPNRVRIFGPDKLVRAAAEKRWDRVKIVCSQPYSKDSPYGLSFVKFHSPPDKDEAEAPSQKVTVTKLGQFRVKEEDDSANSLRPGALFFNRINKAASASASDPAGPSYAAATLQASSAASSASPVPKVGGSSSKLQEPPKGKRKLDLGLEDKKPPSKPSAGPPAPKRPKLPVPSRTPAATPASTPAQKAVPGKPRGEGTEPRGARAGPQELGKILQGVVVVLSGFQNPFRSELRDKALELGAKYRPDWTPDSTHLICAFANTPKYSQVLGLGGRIVRKEWVLDCYRMRRRLPSRRYLMAGLGSSSEDEGDSHSESGEDEAPKLPRKRPQPKAKTQAAGPSSPPRPPTPEETKAPSPGPQDNSDTDGEQSEGRDNGAEDSGDTEDELRRVAKQREQRQPPAPEENGEDPYAGSTDENTDSEAPSEADLPIPELPDFFQGKHFFLYGEFPGDERRKLIRYVTAFNGELEDYMSDRVQFVITAQEWDPNFEEALMENPSLAFVRPRWIYSCNEKQKLLPHQLYGVVPQA", "length": 631 }, "evidence": [ { "id": "RGD:619823", "url": "https://alliancegenome.org/gene/RGD:619823#orthology", "database": "AGR" }, { "id": "HGNC:12828", "url": "https://alliancegenome.org/gene/HGNC:12828#orthology", "database": "AGR" }, { "id": "MGI:99137", "url": "https://alliancegenome.org/gene/MGI:99137#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040822-30", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040822-30#orthology", "database": "AGR" }, { "id": "FB:FBgn0026751", "url": "https://alliancegenome.org/gene/FB:FBgn0026751#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9Y095", "url": "https://www.uniprot.org/uniprotkb/Q9Y095" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "damaged DNA binding", "id": "GO:0003684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003684", "evidence": [ { "database": "UniProtKB", "id": "Q9Y095", "url": "https://www.uniprot.org/uniprotkb/Q9Y095" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "base-excision repair", "id": "GO:0006284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006284", "evidence": [ { "database": "UniProtKB", "id": "Q9Y095", "url": "https://www.uniprot.org/uniprotkb/Q9Y095" } ], "pmid": "" }, { "name": "double-strand break repair via nonhomologous end joining", "id": "GO:0006303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006303", "evidence": [ { "database": "UniProtKB", "id": "Q9Y095", "url": "https://www.uniprot.org/uniprotkb/Q9Y095" } ], "pmid": "" }, { "name": "single strand break repair", "id": "GO:0000012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000012", "evidence": [ { "database": "UniProtKB", "id": "Q9Y095", "url": "https://www.uniprot.org/uniprotkb/Q9Y095" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 336, "end_pos": 338, "annotation": "n_glycosylation_sequon" }, { "start_pos": 577, "end_pos": 579, "annotation": "n_glycosylation_sequon" }, { "start_pos": 99, "end_pos": 101, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9Y095", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9Y095" }, { "id": "PS50172", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50172" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BRCT", "eco_id": "ECO_0000259", "start_pos": 420, "end_pos": 507, "start_aa": "Pro", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 254, 404 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 336, "end_pos": 338 }, { "start_pos": 577, "end_pos": 579 }, { "start_pos": 99, "end_pos": 101 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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Pathway" ] }, { "id": "ETWQLLP", "url": "https://omabrowser.org/oma/group/ETWQLLP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9Y0Z1", "url": "https://www.orthodb.org/?gene=Q9Y0Z1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13052", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13052", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13052:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13052:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14465", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14465", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25793", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25793", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-5689603", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-5689603", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-5696394", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-5696394", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001287243", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287243", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9Y0Z1", "url": "https://www.uniprot.org/uniprotkb/Q9Y0Z1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9Y0Z1-1", "url": "https://www.uniprot.org/uniprotkb/Q9Y0Z1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSNINVNTVPRSSPNANGNPNANPNRSVASEEEEGDGRMSDSGSNSASSQLSRTSSSSSSDSASGSLEDDPDGEDEDMSAQDAGSASETEDDTSTCQSDELELAQLTGRDIFRLPRGLCENAAIFHEFFSLETWQQLPHHLQARLQPMLPDFSRLVSGQAQACAEQQRTLVQLFNGGLQRFGQSPLLQLQRQLEEGNLRPDVLQLRRSIQHSGRREFRFQQAERLSLLAKELFMSREQLLQHAYTSAPPSDGAFGKNLPRPRSRKRKPPTLSIENKFCSQRAKKRYAQELLELIGSLEAKPGDISAEEEEEDEECRQLMDRLAKGPQEFELEETKAPEPAGPGRPSNAADKKCIYNTFFKRRPGVDDDLVLRSMQAEKIPKLNDKNFRKYLRDYKRRKLEQPESPEFDTSEVRLRDICTRAQFVGSFKPGRKPKALMARLNPDPPALVPIGVTPTKNEFVDEEPMLLDEPQQLYGRRAPEDHPEEDLPHKEPPPMPKKVMPAPVVLPQPVPKLEPLNGPITNPKASPTTPNHSNNPITVSATAGHITGSPTREVQIRPPASPRPACFFSLLRDLFVSTPQHRLTYGELQILLSSWREINSDASIPIGEWPRFRPDWSKLLQSAINFLSGDFSSVPADYVPYIEHKTQLGIYQWIGAGRDSDARLLSLCQFWLRTQREKQSQLSPVLISGVHLNSLVDASPTPPPRCPTTWTVRSATQAEILEFQSQERIRFEYPHRPFTYRLNGYESVVGPVKGIYTQGLPLNKARGHAVMVDDRPPFVTILTLVRDATARLPNGEGTRSEISELLKCSQYISQQAADNVLQTIVSGALDRMHGGPDPCVKYDARRKIWIYLHRNRSEAEFEKMHRHNQSLVKQKQQQRKQLNRPKIPDDRSGLAADHQQEQVPALVPAVASPVPVSVQQPVVASLQMKKPLAVKCPPVPPLKYHVPPGTPIGGTIISASSNINANQIPMQQIQKSLLKPVVVPNSAPSPVQRQLATGKSGTFAISKISPTRNTTPILVSTPSGLQTVHVATTPNQAGGSASPTVAKKLTIKKPVPNNKIGNFIIPLDQQQSGPQQQQPTQQGQHVKVQPIAGKPKALTITPRPQMPKNIIRLLPAGGATVTGNSVIGGTKPNSVQILGPRVVPQIQTVRPAQQKIGAVSIVANKPVTSVAATETASPVTMSTISSPVPGGGTIVKMSPQAFANLQQQQQQLKQKVNNASPALNSPQQRIIVGNTAISSNKKIVFQSLGKAAPKILTTSPSGSVTKATTNLSPQQQRIVLQNFKQPVIATNQSGTLTAVGGNATRVIRATPATSVGTGGIVGAGNPQTAGQIITLDSLLQKQPAGGKLLTTAGNNIFQLATSSAGNVITLSPNQTTKQLPTMTRIVSATSTTPATGNASTVVPKIIGKTTVLPGKPLLLHAKTLKQIGGSSVPTTQTTTTTTTAVASAAVGSGSGAGGTVVAGTGATNAAGRTTQNIVIGGQTVKLQGAISARGAGAPVQTVIMGNQLLRLASSTSNSGTTSTSGITTAPKTLLIGPRLAKNVLVANKQITSTANSSVVNSSTTASPAATATATPSNNLVFAVQGNGGQLFFSPGLQGMNLKPLSSLKVIPMAAASASGAAVGGKISVTTAAGETGAKTLTTKLIPATVLKTATGSGN", "length": 1658, "header": "tr|Q9Y0Z1-1|Q9Y0Z1_DROME Isoform 1 of DEUBAD domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG11970 PE=1 SV=1 CANONICAL=Q9Y0Z1-1" }, "isoforms": [ { "isoform_ac": "Q9Y0Z1-1", "url": "https://www.uniprot.org/uniprotkb/Q9Y0Z1/entry#Q9Y0Z1-1", "sequence": { "sequence": "MSNINVNTVPRSSPNANGNPNANPNRSVASEEEEGDGRMSDSGSNSASSQLSRTSSSSSSDSASGSLEDDPDGEDEDMSAQDAGSASETEDDTSTCQSDELELAQLTGRDIFRLPRGLCENAAIFHEFFSLETWQQLPHHLQARLQPMLPDFSRLVSGQAQACAEQQRTLVQLFNGGLQRFGQSPLLQLQRQLEEGNLRPDVLQLRRSIQHSGRREFRFQQAERLSLLAKELFMSREQLLQHAYTSAPPSDGAFGKNLPRPRSRKRKPPTLSIENKFCSQRAKKRYAQELLELIGSLEAKPGDISAEEEEEDEECRQLMDRLAKGPQEFELEETKAPEPAGPGRPSNAADKKCIYNTFFKRRPGVDDDLVLRSMQAEKIPKLNDKNFRKYLRDYKRRKLEQPESPEFDTSEVRLRDICTRAQFVGSFKPGRKPKALMARLNPDPPALVPIGVTPTKNEFVDEEPMLLDEPQQLYGRRAPEDHPEEDLPHKEPPPMPKKVMPAPVVLPQPVPKLEPLNGPITNPKASPTTPNHSNNPITVSATAGHITGSPTREVQIRPPASPRPACFFSLLRDLFVSTPQHRLTYGELQILLSSWREINSDASIPIGEWPRFRPDWSKLLQSAINFLSGDFSSVPADYVPYIEHKTQLGIYQWIGAGRDSDARLLSLCQFWLRTQREKQSQLSPVLISGVHLNSLVDASPTPPPRCPTTWTVRSATQAEILEFQSQERIRFEYPHRPFTYRLNGYESVVGPVKGIYTQGLPLNKARGHAVMVDDRPPFVTILTLVRDATARLPNGEGTRSEISELLKCSQYISQQAADNVLQTIVSGALDRMHGGPDPCVKYDARRKIWIYLHRNRSEAEFEKMHRHNQSLVKQKQQQRKQLNRPKIPDDRSGLAADHQQEQVPALVPAVASPVPVSVQQPVVASLQMKKPLAVKCPPVPPLKYHVPPGTPIGGTIISASSNINANQIPMQQIQKSLLKPVVVPNSAPSPVQRQLATGKSGTFAISKISPTRNTTPILVSTPSGLQTVHVATTPNQAGGSASPTVAKKLTIKKPVPNNKIGNFIIPLDQQQSGPQQQQPTQQGQHVKVQPIAGKPKALTITPRPQMPKNIIRLLPAGGATVTGNSVIGGTKPNSVQILGPRVVPQIQTVRPAQQKIGAVSIVANKPVTSVAATETASPVTMSTISSPVPGGGTIVKMSPQAFANLQQQQQQLKQKVNNASPALNSPQQRIIVGNTAISSNKKIVFQSLGKAAPKILTTSPSGSVTKATTNLSPQQQRIVLQNFKQPVIATNQSGTLTAVGGNATRVIRATPATSVGTGGIVGAGNPQTAGQIITLDSLLQKQPAGGKLLTTAGNNIFQLATSSAGNVITLSPNQTTKQLPTMTRIVSATSTTPATGNASTVVPKIIGKTTVLPGKPLLLHAKTLKQIGGSSVPTTQTTTTTTTAVASAAVGSGSGAGGTVVAGTGATNAAGRTTQNIVIGGQTVKLQGAISARGAGAPVQTVIMGNQLLRLASSTSNSGTTSTSGITTAPKTLLIGPRLAKNVLVANKQITSTANSSVVNSSTTASPAATATATPSNNLVFAVQGNGGQLFFSPGLQGMNLKPLSSLKVIPMAAASASGAAVGGKISVTTAAGETGAKTLTTKLIPATVLKTATGSGN", 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"PubMed", "url": "https://glygen.org/publication/PubMed/40245499" } ], "filter_code": "00000000000000001000.0000000.00000001000000.1000000.0100000000.110100100001111011.10000.01000" }, { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1314, "start_aa": "Ser", "end_pos": 1314, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1314", "evidence": [ { "id": "28604694", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/28604694" }, { "id": "Q9Y0Z1", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9Y0Z1" }, { "id": "33925313", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33925313" }, { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" } ], "filter_code": "00000000000000010000.0000000.00000001000000.1000000.0100000000.110100100001111011.10000.01000" }, { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1362, "start_aa": "Ser", "end_pos": 1362, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1362", "evidence": [ { "id": "28604694", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/28604694" }, { "id": "Q9Y0Z1", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9Y0Z1" }, { "id": "33925313", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33925313" }, { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" } ], "filter_code": "00000000000000010000.0000000.00000001000000.1000000.0100000000.110100100001111011.10000.01000" }, { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1387, "start_aa": "Ser", "end_pos": 1387, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1387", "evidence": [ { "id": "28604694", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/28604694" }, { "id": "Q9Y0Z1", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9Y0Z1" }, { "id": "33925313", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33925313" }, { "id": "40245499", "database": "PubMed", "url": 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"https://glygen.org/publication/PubMed/40245499" } ], "filter_code": "00000000000000010000.0000000.00000001000000.1000000.0100000000.110100100001111011.10000.01000" }, { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1514, "start_aa": "Ser", "end_pos": 1514, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1514", "evidence": [ { "id": "28604694", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/28604694" }, { "id": "Q9Y0Z1", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9Y0Z1" }, { "id": "33925313", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33925313" }, { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" } ], "filter_code": "00000000000000010000.0000000.00000001000000.1000000.0100000000.110100100001111011.10000.01000" }, { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1515, "start_aa": "Thr", "end_pos": 1515, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1515", "evidence": [ { "id": "28604694", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/28604694" }, { "id": "Q9Y0Z1", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9Y0Z1" }, { "id": "33925313", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33925313" }, { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" } ], "filter_code": "00000000000000001000.0000000.00000001000000.1000000.0100000000.110100100001111011.10000.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1574, "start_aa": "Thr", "end_pos": 1574, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1574", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": 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"O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1629, "start_aa": "Thr", "end_pos": 1629, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1629", "evidence": [ { "id": "28604694", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/28604694" }, { "id": "Q9Y0Z1", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9Y0Z1" }, { "id": "33925313", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33925313" }, { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" } ], "filter_code": "00000000000000001000.0000000.00000001000000.1000000.0100000000.110100100001111011.10000.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 701, "start_aa": "Thr", "end_pos": 701, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr701", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 912, "start_aa": "Ser", "end_pos": 912, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser912", "evidence": [ { "id": "28604694", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/28604694" }, { "id": "Q9Y0Z1", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9Y0Z1" }, { "id": "33925313", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33925313" }, { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" } ], "filter_code": "00000000000000010000.0000000.00000001000000.1000000.0100000000.110100100001111011.10000.01000" }, { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 986, "start_aa": "Ser", "end_pos": 986, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser986", "evidence": [ { "id": "28604694", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/28604694" }, { "id": "Q9Y0Z1", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9Y0Z1" }, { "id": "33925313", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33925313" }, { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" } ], "filter_code": "00000000000000010000.0000000.00000001000000.1000000.0100000000.110100100001111011.10000.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_reported_with_glycan", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9Y0Z1", "url": "https://www.uniprot.org/uniprotkb/Q9Y0Z1" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9Y0Z1", "url": "https://www.uniprot.org/uniprotkb/Q9Y0Z1" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9Y0Z1", "url": "https://www.uniprot.org/uniprotkb/Q9Y0Z1" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9Y0Z1", "url": "https://www.uniprot.org/uniprotkb/Q9Y0Z1" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9Y0Z1", "url": "https://www.uniprot.org/uniprotkb/Q9Y0Z1" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9Y0Z1", "url": "https://www.uniprot.org/uniprotkb/Q9Y0Z1" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9Y0Z1", "url": "https://www.uniprot.org/uniprotkb/Q9Y0Z1" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9Y0Z1", "url": "https://www.uniprot.org/uniprotkb/Q9Y0Z1" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9Y0Z1", "url": "https://www.uniprot.org/uniprotkb/Q9Y0Z1" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9Y0Z1", "url": "https://www.uniprot.org/uniprotkb/Q9Y0Z1" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9Y0Z1", "url": "https://www.uniprot.org/uniprotkb/Q9Y0Z1" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] }, { "title": "A mutant O-GlcNAcase enriches Drosophila developmental regulators.", "journal": "Nature chemical biology", "date": "2017", "authors": "Selvan N, Williamson R, Mariappa D, Campbell DG, Gourlay R, Ferenbach AT, Aristotelous T, Hopkins-Navratilova I, Trost M, van Aalten DMF", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9Y0Z1", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9Y0Z1" } ], "reference": [ { "type": "PubMed", "id": "28604694", "url": "https://glygen.org/publication/PubMed/28604694" } ] }, { "title": "Drosophila O-GlcNAcase Mutants Reveal an Expanded Glycoproteome and Novel Growth and Longevity Phenotypes.", "journal": "Cells", "date": "2021", "authors": "Akan I, Halim A, Vakhrushev SY, Clausen H, Hanover JA", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9Y0Z1", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9Y0Z1" } ], "reference": [ { "type": "PubMed", "id": "33925313", "url": "https://glygen.org/publication/PubMed/33925313" } ] }, { "title": "Quantitative and site-specific chemoproteomic profiling of O-GlcNAcylation in Drosophila.", "journal": "Bioorganic & medicinal chemistry", "date": "2025-04-10", "authors": "Lei Cong, Chen Zihan, Hao Yi, Huang Wanping, Chu Tianyu, Xiao Kangming, Zhang Che, Zhou Wen, Li Chenjian, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9Y0Z1", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9Y0Z1" } ], "reference": [ { "type": "PubMed", "id": "40245499", "url": "https://glygen.org/publication/PubMed/40245499" } ] } ], "pathway": [ { "id": "dme:Dmel_CG11970", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG11970", "resource": "KEGG Pathway" }, { "id": "R-DME-5689603", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-5689603", "resource": "Reactome", "description": "UCH proteinases" }, { "id": "R-DME-5696394", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-5696394", "resource": "Reactome", "description": "DNA Damage Recognition in GG-NER" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M2B866-1", "protein_name": "Nuclear factor related to kappa-B-binding protein", "gene_name": "nfrkb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDALDHMLTDPLESAMDQDGRVMEECMLGNCRVRVPEDLLEDPEIFFSVLSESTWTDVLTEAQRTHLRQLLPQFPEENMAEQNSIIGDLFNNKNFLFGNPLHIAQKLFRDGHFNPEVVKYRQLCAKSQKKRQIYSLQQYYHKLLKQILVSRKELLDLAVRSGPELAVKRRYPAASHKEMLEQRVRRRVGHIIKDVKTECGDSNVSSDEDDSSSWLPVPQSPSSPTPTFSLRVLPSLSTQDMKTRDKPELGEKELRAMLHRHREKRKRQPDHPDLMTSDLHLGDIMSRVNIGRKGSVTVFDLAIPKKKIKEEKRKKKMRPIKMESEEVCDVQMSAPPMNPGLTDVPAAPPQSVKEEPIDEPQTSPDTVEEIAMSFFHLLEDILRLEGLATSSTMEEKVQQWQSSPASTLNPWFSMAPCWSEVVVPALQFLAGESKAGVMALPTGFIPFVEFKEVSQQWKWIGSSQDGDKDLSALCQLWLESKDHVIVKQEGEETAELTPPTPRVWTDYVVRPSTGEERHVFQEQEQQRYDQPHKAFTYRMHGFESVVGPVKGVFDKETSLNKAREHSLLRSDRPAYVTILSLVRDAAARLPNGEGTRAEICELLKDSQFLAPDVTSAQVNTVVSGALDRLHYEKDPCVKYDIGRKLWIYLHRDRSQEEFERIHQAQAAAAKAKKALQQKPKPAPKPKAGGKEPGSKNGIAEAGQSTSNEGIAIAATSLSQTPSTPTQSTPGTPKSPLPPTSATPTKVAAPEPIKTNPSVLLVSPPTMPQLGTLLSASQPSPQVSQQASPQSATRVVAHSAATGSLPQVRVVTAQPSLHTSTAGQAATLVHQSPHHIRVPVTVAHGKNITQAVVTLPLRNQSAGSPIQVQASRGQASLTVPGLASAVTVTKPQTSSPASPAHNQTAPAVLQGVSSQSIIKQVAITGQLGVKTQSGAGIPLTATNLRIQGKDVLRLPPSSITTDAKGQTVLRITPDMMATLTKSPVATVKLTPDMLSSATSSGSKSISATLHVSQPQPSPPTSSTTASENLAVKTPATLVKVHPELKTACDTAIRLMPALAVTMADSKARTFSTVTSSDSKAGTTIRIVPNLGVIPQKQGQAVSIATTTTSTKPITVSSGAATVTIATSGVAGAKGVTLGTAGTGSTLSLGTAAATVRQVPVSATVVTTQTGKLPTRITVPLSVLSQPLKNKSVVTTPILKGNISTNISNLGRNIILTTMPAGTKLIAGNKPVSFVTAQQLQQLQQQGQATQVRIQTVPAQQLQRTAASSPKSTVSTVVVSTAPSPKTNPDPQ", "length": 1290 }, "evidence": [ { "id": "RGD:1310558", "url": "https://alliancegenome.org/gene/RGD:1310558#orthology", "database": "AGR" }, { "id": "HGNC:7802", "url": "https://alliancegenome.org/gene/HGNC:7802#orthology", "database": "AGR" }, { "id": "MGI:2442410", "url": "https://alliancegenome.org/gene/MGI:2442410#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-6419", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-6419#orthology", "database": "AGR" }, { "id": "FB:FBgn0027503", "url": "https://alliancegenome.org/gene/FB:FBgn0027503#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A9J7JFS6-1", "protein_name": "Nuclear factor related to kappa-B-binding protein", "gene_name": "Nfrkb", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDSLDHMLTDPLELGPCGDGHGTRIMEDCLLGGTRVSLPEDLLEDPEIFFDVVSLSTWQEVLSDSQREHLQQFLPQFPTDNVEQQNELILALFSGENFRFGNPLHIAQKLFRDGHFNPEVVKYRQLCFKSQYKRYLNSQQQYFHRLLKQILASRSDLLEMARRSGPALPFRHKRHSPSRSPEEREWRTQQRYLKVLREVKEECGDTALSSDEEATLDLQEKFSFEDLSSWLPSSPARSPSPAVPLRVVPTLSTTDMKTADKIELGDSDLKIMLKKHHEKRKHQPDHPDLLTGDLTLSDIMTRVNAGRKGSLAALYDLAVLKKKVKEKEKKKKIKLIKSEAEDLAEPLSNSEGVPTLSQAPSPLAISSIKEEPLEDIKPCLGINELFPSFFSLLLEILLESQASLPMLEDRVLDWQASPASSLNSWFSAAPNWAELVLPALQYLAGESRAVPSSFSPFVEFKEKTQQWKLLGQYQDNEKELAALFHLWLETKDQTFCKQENEDSSDAMTPVPRVRTDYVVRPSTGEEKRVFQEQERYRYSQPHKAFTFRMHGFESVVGPVKGVFDKETSLNKAREHSLLRSDRPAYVTILSLVRDAAARLPNGEGTRAEICELLKDSQFLAPDVTSTQVNTVVSGALDRLHYEKDPCVKYDIGRKLWIYLHRDRSEEEFERIHQAQAAAAKARKALQQKPKPPSKVKSSNKESSLKGLSGPSEQSQMSLSDSSMPPTPVTPVTPTTPALPTTPISPPPVSAVNKSGSTTVSEPAKSSSGVLLVSSPTMPQLGTMLSPTSIQTPPSSQATARVVSHSSSAGLPQVRVVAQPSLPAVSQQSVGPTQTLPQMPAGPQIRVPVTATQTKVVPQAVVATVPVKGQTAAASVQRPAPGQTGLTVNLPAAVSPVSKPAMSSPGNSAPSASTTAVIQNVTGQNIIKQVSITGQLGVKPQTGNSIPLTATNFRIQGKDVLRLPPSSITTDAKGQTVLRITPDMMATLAKSQVTTVKLTQDLFGTGSGTAGKGISATLHVTSNPVHATDSPAKAPSASVPSSAPAGTTVVKVTPDLKPTEASNSAFRLMPALGVSVADQKGKNTVASSEAKPAATIRIVQGLGVMPPKAGQTITVAAHAKQGASVAGGSGTVHSSTVSLPSISATVSKTVAVASGATSTPISIGTGAPTVRQVPVNTTVVSTSQSGKLPTRITVPLSVISQPMKGKSVVTAPIIKGNLGANLSGLGRNIILTTMPAGTKLIAGNKPVSFLTAQQLQQLQQQGQATQVRIQTVPASHLQQGTASGSSKAVSTVVVTTAPSPKQAPEQQ", "length": 1306 }, "evidence": [ { "id": "Q9Y0Z1", "url": "https://omabrowser.org/oma/group/Q9Y0Z1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D4A421-1", "protein_name": "Nuclear factor related to kappa-B-binding protein", "gene_name": "Nfrkb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSLDHMLTDPLELGPCGDGHSTGIMEDCLLGGTRVSLPEDLLEDPEIFFDVVSLSTWQEVLSDSQREHLQQFLPQFPTDTVEQQNELILALFSGENFRFGNPLHIAQKLFRDGHFNPEVVKYRQLCFKSQYKRYLSSQQQYFHRLLRQILASRSDLLEMARTSGPALPFRHKHHSPSRSPEEREWRTQQRYLKVLREVKEECGDTALSSDEEATLDLQEKFSFEDLSSWLPSSPARSPSPAVPLRVVPTLSTTDMKTADKIELGDSDLKLMLKKHHEKRKHQPDHPDLLTGDLTLSDIMTRVNAGRKGSLAALYDLAVLKKKVKEKEEKKKKKIKLIKSEAEDLAEPLSNTEGVPTLSQAPSPLAISSIKEEPLEDIKPCLGINEISSSFFSLLLEILLLESQASLPMLEDRVLDWQSSPASSLNSWFSAAPNWAELVLPALQYLAGESRAVPSSFSPFVEFKEKTQQWKLLGQSQDNEKELAALFHLWLETKDQAFCKQENEDSSDAMTPVPRVRTDYVVRPSTGEEKRVFQEQERYRYSQPHKAFTFRMHGFESVVGPVKGVFDKETSLNKAREHSLLRSDRPAYVTILSLVRDAAARLPNGEGTRAEICELLKDSQFLAPDVTSTQVNTVVSGALDRLHYEKDPCVKYDIGRKLWIYLHRDRSEEEFERIHQAQAAAAKARKALQQKPKPPSKVKSSNKEGSVKGLSGPSEPSQMSLSDSSMPPTPVTPVTPTTPALPTPISPPPVSAVSRSGSTTVSEPAKSSSGVLLVSSPTMPQLGTMLSPASIQTPPSSQTTARVVSHSSSAGLPQVRVVAQPSLPAVSQQSVGPAQPLPQMPAGPQIRVPVTATQTKVVPQAVVATVPVKGQTTAASVQRPGPAQTGLTVTSLPAAVSPGSKTAMSSPGSSAPSASTTAVIQNVTGQNIIKQVSITGQLGVKPQTGNSIPLTATNFRIQGKDVLRLPPSSITTDAKGQTVLRITPDMMATLAKSQVTTVKLTQDLFGAGSGTAGKGISATLHVTSNPVHAADSPAKAPSASVPSSAPAGTTVVKVTPDLKPTETSSSAFRLMPALGVSVADQKGKNTVASSEAKPAATIRIVQGLGVMPPKAGQTITVAAHAKQGASVAGGSGTVHSSTVSLPSINATVSKTVAVASGATSTPISIGTGAPTVRQVPVNTTVVSTSQSGKLPTRITVPLSVISQPMKGKSVVTAPIIKGNLGANLSGLGRNIILTTMPAGAKLIAGNKPVSFLTAQQLQQLQQQGQATQVRIQTVPASHLQQGTASGSSKAVSTVVVTTAPSPKQAPEQQ", "length": 1309 }, "evidence": [ { "id": "RGD:1310558", "url": "https://alliancegenome.org/gene/RGD:1310558#orthology", "database": "AGR" }, { "id": "HGNC:7802", "url": "https://alliancegenome.org/gene/HGNC:7802#orthology", "database": "AGR" }, { "id": "MGI:2442410", "url": "https://alliancegenome.org/gene/MGI:2442410#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-6419", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-6419#orthology", "database": "AGR" }, { "id": "FB:FBgn0027503", "url": "https://alliancegenome.org/gene/FB:FBgn0027503#orthology", "database": "AGR" }, { "id": "Q9Y0Z1", "url": "https://omabrowser.org/oma/group/Q9Y0Z1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6P4R8-1", "protein_name": "Nuclear factor related to kappa-B-binding protein", "gene_name": "NFRKB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDSLDHMLTDPLELGPCGDGHGTRIMEDCLLGGTRVSLPEDLLEDPEIFFDVVSLSTWQEVLSDSQREHLQQFLPQFPEDSAEQQNELILALFSGENFRFGNPLHIAQKLFRDGHFNPEVVKYRQLCFKSQYKRYLNSQQQYFHRLLKQILASRSDLLEMARRSGPALPFRQKRPSPSRTPEEREWRTQQRYLKVLREVKEECGDTALSSDEEDLSSWLPSSPARSPSPAVPLRVVPTLSTTDMKTADKVELGDSDLKIMLKKHHEKRKHQPDHPDLLTGDLTLNDIMTRVNAGRKGSLAALYDLAVLKKKVKEKEEKKKKKIKTIKSEAEDLAEPLSSTEGVAPLSQAPSPLAIPAIKEEPLEDLKPCLGINEISSSFFSLLLEILLLESQASLPMLEERVLDWQSSPASSLNSWFSAAPNWAELVLPALQYLAGESRAVPSSFSPFVEFKEKTQQWKLLGQSQDNEKELAALFQLWLETKDQAFCKQENEDSSDATTPVPRVRTDYVVRPSTGEEKRVFQEQERYRYSQPHKAFTFRMHGFESVVGPVKGVFDKETSLNKAREHSLLRSDRPAYVTILSLVRDAAARLPNGEGTRAEICELLKDSQFLAPDVTSTQVNTVVSGALDRLHYEKDPCVKYDIGRKLWIYLHRDRSEEEFERIHQAQAAAAKARKALQQKPKPPSKVKSSSKESSIKVLSSGPSEQSQMSLSDSSMPPTPVTPVTPTTPALPAIPISPPPVSAVNKSGPSTVSEPAKSSSGVLLVSSPTMPHLGTMLSPASSQTAPSSQAAARVVSHSGSAGLSQVRVVAQPSLPAVPQQSGGPAQTLPQMPAGPQIRVPATATQTKVVPQTVMATVPVKAQTTAATVQRPGPGQTGLTVTSLPATASPVSKPATSSPGTSAPSASTAAVIQNVTGQNIIKQVAITGQLGVKPQTGNSIPLTATNFRIQGKDVLRLPPSSITTDAKGQTVLRITPDMMATLAKSQVTTVKLTQDLFGTGGNTTGKGISATLHVTSNPVHAADSPAKASSASAPSSTPTGTTVVKVTPDLKPTEASSSAFRLMPALGVSVADQKGKSTVASSEAKPAATIRIVQGLGVMPPKAGQTITVATHAKQGASVASGSGTVHTSAVSLPSMNAAVSKTVAVASGAASTPISISTGAPTVRQVPVSTTVVSTSQAGKLPTRITVPLSVISQPMKGKSVVTAPIIKGNLGANLSGLGRNIILTTMPAGTKLIAGNKPVSFLTAQQLQQLQQQGQATQVRIQTVPASHLQQGTASGSSKAVSTVVVTTAPSPKQAPEQQ", 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"MDSLDHMLTDPLELGPCGDGHSTGIMEDCLLGGTRVSLPEDLLEDPEIFFDVVSLSTWQEVLSDSQREHLQQFLPRFPADSVEQQRELILALFSGENFRFGNPLHIAQKLFRDGHFNPEVVKYRQLCFKSQYKRYLNSQQQYFHRLLKQILASRSDLLEMARRSGPALPFPHKHHSPSRSPEEREWRTQQRYLKVLREVKEECGDTALSSDEEDLSSWLPSSPARSPSPAVPLRVVPTLSTTDMKTADKIELGDSDLKLMLKKHHEKRKHQPDHPDLLTGDLTLSDIMTRVNAGRKGSLAALYDLAVLKKKVKEKEEKKKKKIKLIKSEAEDLAEPLSSTEGVPTLSQAPSPLAISSIKEEPLEDIKPCLGINEISSSFFSLLLEILLLESQASLPMLEDRVLDWQSSPASSLNSWFSAAPNWAELVLPALQYLAGESRAVPSSFSPFVEFKEKTQQWKLLGQSQDNEKELAALFHLWLETKDQAFCKENEDSSDAMTPVPRVRTDYVVRPSTGEEKRVFQEQERYRYSQPHKAFTFRMHGFESVVGPVKGVFDKETSLNKAREHSLLRSDRPAYVTILSLVRDAAARLPNGEGTRAEICELLKDSQFLAPDVTSTQVNTVVSGALDRLHYEKDPCVKYDIGRKLWIYLHRDRSEEEFERIHQAQAAAAKARKALQQKPKPPSKVKSSNKEGSTKGLSGPSEQSQMSLSDSSMPPTPVTPVTPTTPALPTPISPPPVSAVNRSGSSTVSEPAQSSSGVLLVSSPTMPQLGTMLSPASIQTPPSSQATARVVSHSSSAGLPQVRVVAQPSLPAVSQQSVGPAQPLPQMPAGPQIRVPVTATQTKVVPQAVMATVPVKGQTAAASVQRPGPGQTGLTVTNLPAAVSPVSKTAMSSPGNSAPSASTTAVIQNVTGQNIIKQVSITGQLGVKPQTGSSIPLTATNFRIQGKDVLRLPPSSITTDAKGQTVLRITPDMMATLAKSQVTTVKLTQDLFGAGSGTAGKGISATLHVTSNPVHAADSPAKAPSASVPSSAPAGTTVVKVTPDLKPTETANSAFRLMPALGVSVADQKGKNTVASSEAKPAATIRIVQGLGVMPPKAGQTITVAAHAKQGASVAGGSGTVHSSTVSLPSINAAVSKTVAVASGATSTPISIGTGAPTVRQVPVNTTVVSTSQSGKLPTRITVPLSVISQPMKGKSVVTAPIIKGNLGANLSGLGRNIILTTMPAGTKLIAGNKPVSFLTAQQLQQLQQQGQATQVRIQTVPASHLQQGTASGSSKAVSTVVVTTAPSPKQAPEQQ", 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"Q9Y0Z1", "url": "https://www.uniprot.org/uniprotkb/Q9Y0Z1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Ino80 complex", "id": "GO:0031011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031011", "evidence": [ { "database": "UniProtKB", "id": "Q9Y0Z1", "url": "https://www.uniprot.org/uniprotkb/Q9Y0Z1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1013, "end_pos": 1015, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1218, "end_pos": 1220, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1270, "end_pos": 1272, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1291, "end_pos": 1293, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1302, "end_pos": 1304, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1373, "end_pos": 1375, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1397, "end_pos": 1399, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1555, "end_pos": 1557, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1560, "end_pos": 1562, "annotation": "n_glycosylation_sequon" }, { "start_pos": 25, "end_pos": 27, "annotation": "n_glycosylation_sequon" }, { "start_pos": 531, "end_pos": 533, "annotation": "n_glycosylation_sequon" }, { "start_pos": 855, "end_pos": 857, "annotation": "n_glycosylation_sequon" }, { "start_pos": 868, "end_pos": 870, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9Y0Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9Y0Z1" }, { "id": "PS51916", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51916" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DEUBAD", "eco_id": "ECO_0000259", "start_pos": 115, "end_pos": 238, "start_aa": "Pro", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 701, 912, 986, 1258, 1314, 1362, 1387, 1513, 1514, 1515, 1574, 1616, 1629 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1013, "end_pos": 1015 }, { "start_pos": 1218, "end_pos": 1220 }, { "start_pos": 1270, "end_pos": 1272 }, { "start_pos": 1291, "end_pos": 1293 }, { "start_pos": 1302, "end_pos": 1304 }, { "start_pos": 1373, "end_pos": 1375 }, { "start_pos": 1397, "end_pos": 1399 }, { "start_pos": 1555, "end_pos": 1557 }, { "start_pos": 1560, "end_pos": 1562 }, { "start_pos": 25, "end_pos": 27 }, { "start_pos": 531, "end_pos": 533 }, { "start_pos": 855, "end_pos": 857 }, { "start_pos": 868, "end_pos": 870 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 13 }, { "field": "total_sites", "count": 13 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 13 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 11 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 13 }, { "field": "exact_o_linked_sites", "count": 13 }, { "field": "exact_o_linked_glycan_sites", "count": 11 }, { "field": "exact_o_linked_glycans", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { 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"sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 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"field": "total", "count": 14 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "Q9Y104-1", "uniprot_ac": "Q9Y104", "uniprot_id": "Q9Y104_DROME", "mass": { "chemical_mass": 40798.0, "monoisotopic_mass": 40798.0 }, "refseq": { "ac": "NP_001189318", "name": "uncharacterized protein, isoform B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001189318" }, "gene_names": [ { "name": "Dmel\\CG2217", "type": "recommended", "evidence": [ { "id": "Q9Y104", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9Y104" } ] }, { "name": "BcDNA:GH11688", "type": "synonym", "evidence": [ { "id": "NP_001189318", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001189318" }, { "id": "Q9Y104", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9Y104" } ] }, { "name": "CG2217", "type": "synonym", "evidence": [ { "id": "NP_001189318", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001189318" }, { "id": "Q9Y104", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9Y104" } ] }, { "name": "Dmel\\CG2217", "type": "synonym", "evidence": [ { "id": "NP_001189318", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001189318" } ] }, { "name": "Dmel_CG2217", "type": "synonym", "evidence": [ { "id": "Q9Y104", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9Y104" } ] } ], "protein_names": [ { "name": "DUF4780 domain-containing protein", "type": "recommended", "evidence": [ { "id": "Q9Y104", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9Y104/entry#names_and_taxonomy" } ] }, { "name": "CG2217-PB", "type": "synonym", "evidence": [ { "id": "NP_001189318", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001189318" } ] }, { "name": "uncharacterized protein, isoform B", "type": "synonym", "evidence": [ { "id": "NP_001189318", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001189318" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9Y104", "url": "https://www.uniprot.org/uniprotkb/Q9Y104" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG2217", "url": "https://www.uniprot.org/uniprotkb/Q9Y104", "locus": { "chromosome": "3R", "start_pos": 30418767, "end_pos": 30422971, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0027544", "url": "https://www.ensemblgenomes.org/id/FBgn0027544" } ] } } ], "crossref": [ { "id": "FB:FBgn0027544", "url": "https://alliancegenome.org/gene/FB:FBgn0027544", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0027544", "url": "https://bgee.org/?page=gene&gene_id=FBgn0027544", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0027544", "url": "https://flybase.org/reports/FBgn0027544", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "43607", "url": "https://www.ncbi.nlm.nih.gov/gene/43607", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR031961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG2217", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG2217", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SEWFKRN", "url": "https://omabrowser.org/oma/group/SEWFKRN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9Y104", "url": "https://www.orthodb.org/?gene=Q9Y104", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF16012", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16012", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001189318", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001189318", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9Y104", "url": "https://www.uniprot.org/uniprotkb/Q9Y104", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9Y104-1", "url": "https://www.uniprot.org/uniprotkb/Q9Y104-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNSLEVNESDAAPEASPNRNPSVDSGPGFVRLKTRQKKLLRKALHGGLTREKALEVVQALPIVKGLLPDPYENQTANPYPSGLVECVRIGLAAESAGTSLTSEQMTMIKEAIIDVTVEKSGSQKPQFEGCVARRGWLLVTCSNSSTSEWFKQNFCHIQSKVTTKLKLMDESELPRRNVVLGYFPDSLTTSSQKVLEIIQAQNPVSTAEWRVMNRLTHGELLHLSMAVDNESHKKLIELNGTISFRFGRVKLCLKNSLDRKSVLNGRKETSPNRKSLDKAAVSREIVPAPQEPVITNDSPWNQSHNPWLSHSNPMMQWNQQQMLRYDPYSPRELPPNFLHASYSGLGYGNEGDRRLRPRTWPGNC", "length": 364, "header": "tr|Q9Y104-1|Q9Y104_DROME Isoform 1 of DUF4780 domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG2217 PE=4 SV=1 CANONICAL=Q9Y104-1" }, "isoforms": [ { "isoform_ac": "Q9Y104-1", "url": "https://www.uniprot.org/uniprotkb/Q9Y104/entry#Q9Y104-1", "sequence": { "sequence": "MNSLEVNESDAAPEASPNRNPSVDSGPGFVRLKTRQKKLLRKALHGGLTREKALEVVQALPIVKGLLPDPYENQTANPYPSGLVECVRIGLAAESAGTSLTSEQMTMIKEAIIDVTVEKSGSQKPQFEGCVARRGWLLVTCSNSSTSEWFKQNFCHIQSKVTTKLKLMDESELPRRNVVLGYFPDSLTTSSQKVLEIIQAQNPVSTAEWRVMNRLTHGELLHLSMAVDNESHKKLIELNGTISFRFGRVKLCLKNSLDRKSVLNGRKETSPNRKSLDKAAVSREIVPAPQEPVITNDSPWNQSHNPWLSHSNPMMQWNQQQMLRYDPYSPRELPPNFLHASYSGLGYGNEGDRRLRPRTWPGNC", "length": 364, "header": "tr|Q9Y104-1|Q9Y104_DROME Isoform 1 of DUF4780 domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG2217 PE=4 SV=1 CANONICAL=Q9Y104-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": 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"url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9Y104", "url": "https://www.uniprot.org/uniprotkb/Q9Y104" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, 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Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9Y104", "url": "https://www.uniprot.org/uniprotkb/Q9Y104" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9Y104", "url": "https://www.uniprot.org/uniprotkb/Q9Y104" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9Y104", "url": "https://www.uniprot.org/uniprotkb/Q9Y104" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9Y104", "url": "https://www.uniprot.org/uniprotkb/Q9Y104" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"https://monarchinitiative.org/disease/MONDO:0001056", "name": "cancer of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer risk after h. pylori infection", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer, somatic", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric tumor", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric tumour", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant stomach neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of body of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of greater curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of body of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of greater curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "stomach cancer", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "Ca body - stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "ca greater curvature of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of body of stomach", "description": "" }, { "id": "MIM:613659", "resource": "MIM", "url": "https://www.omim.org/entry/613659", "name": "Gastric cancer", "description": "Gastric cancer" } ], "unlinked_id_list": [], "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ] }, { "disease_id": "DOID:10652", "recommended_name": { "id": "DOID:10652", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid." }, "synonyms": [ { "id": "DOID:10652", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10652", "name": "Alzheimer disease", "description": "" }, { "id": "DOID:10652", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10652", "name": "Alzheimers dementia", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ] }, { "disease_id": "DOID:12858", "recommended_name": { "id": "DOID:12858", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12858", "name": "Huntington's disease", "description": "A neurodegenerative disease that has_material_basis_in autosomal dominant inheritance and is characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia and has_material_basis_in expansion of CAG triplet repeats (glutamine) resulting in neuron degeneration affecting muscle coordination, cognitive abilities." }, "synonyms": [ { "id": "DOID:12858", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12858", "name": "HD", "description": "" }, { "id": "DOID:12858", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12858", "name": "Huntington disease", "description": "" }, { "id": "DOID:12858", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12858", "name": "Huntington's chorea", "description": "" }, { "id": "MONDO:0007739", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007739", "name": "Huntington disease", "description": "Huntington 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"resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007739", "name": "Huntington's disease", "description": "" }, { "id": "MIM:143100", "resource": "MIM", "url": "https://www.omim.org/entry/143100", "name": "Huntington disease", "description": "Huntington disease" } ], "unlinked_id_list": [], "evidence": [ { "id": "12858", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12858" } ] }, { "disease_id": "DOID:14330", "recommended_name": { "id": "DOID:14330", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions." }, "synonyms": [ { "id": "DOID:14330", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14330", "name": "Parkinson disease", "description": "" }, { "id": "DOID:14330", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14330", "name": "paralysis agitans", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "late-onset Parkinson disease", "description": "A Parkinson disease that begins after around the age of 50." }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "LOPD", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "PARK", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "PD", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "Parkinson disease, age of onset, modifier, Multifactorial", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "Parkinson disease, late-onset", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "Parkinson disease, late-onset, susceptibility to, Multifactorial", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "Parkinson disease, susceptibility to, Multifactorial", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "autosomal dominant late-onset Parkinson disease", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "hereditary late onset Parkinson disease", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "hereditary late-onset Parkinson disease", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "late-onset Parkinson disease", "description": "" }, { "id": "MIM:168600", "resource": "MIM", "url": "https://www.omim.org/entry/168600", "name": "Parkinson disease", "description": "Parkinson disease" } ], "unlinked_id_list": [], "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ] }, { "disease_id": "DOID:1826", "recommended_name": { "id": "DOID:1826", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1826", "name": "epilepsy", "description": "A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions." }, "synonyms": [ { "id": "DOID:1826", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1826", "name": "epilepsy syndrome", "description": "" }, { "id": "DOID:1826", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1826", "name": "epileptic syndrome", "description": "" } ], "unlinked_id_list": [ "DOID:3331", "DOID:0050702", "DOID:0060172", "DOID:0050706", "DOID:0050705", "DOID:0050703", "DOID:0050701", "DOID:0060169" ], "evidence": [ { "id": "1826", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1826" } ] }, { "disease_id": "DOID:1849", "recommended_name": { "id": "DOID:1849", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1849", "name": "cannabis dependence", "description": "A drug dependence that involves the continued use of cannabis despite problems related to use of the substance." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "1849", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1849" } ] }, { "disease_id": "DOID:2377", "recommended_name": { "id": "DOID:2377", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2377", "name": "multiple sclerosis", "description": "A demyelinating disease that involves damage to the fatty myelin sheaths around the axons of the brain and spinal cord resulting in demyelination and scarring." }, "synonyms": [ { "id": "DOID:2377", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2377", "name": "Generalized multiple sclerosis", "description": "" }, { "id": "DOID:2377", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2377", "name": "insular sclerosis", "description": "" }, { "id": "MONDO:0012956", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012956", "name": "multiple sclerosis, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012956", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012956", "name": "MS2", "description": "" }, { "id": "MONDO:0012956", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012956", "name": "multiple sclerosis, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012957", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012957", "name": "multiple sclerosis, susceptibility to, 3", "description": "" }, { "id": "MONDO:0012957", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012957", "name": "MS3", "description": "" }, { "id": "MONDO:0012957", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012957", "name": "multiple sclerosis, susceptibility to, 3", "description": "" }, { "id": "MONDO:0012958", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012958", "name": "multiple sclerosis, susceptibility to, 4", "description": "" }, { "id": "MONDO:0012958", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012958", "name": "MS4", "description": "" }, { "id": "MONDO:0012958", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012958", "name": "multiple sclerosis, susceptibility to, 4", "description": "" }, { "id": "MIM:612595", "resource": "MIM", "url": "https://www.omim.org/entry/612595", "name": "Multiple sclerosis 3", "description": "Multiple sclerosis 3" } ], "unlinked_id_list": [], "evidence": [ { "id": "2377", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2377" } ] }, { "disease_id": "DOID:3119", "recommended_name": { "id": "DOID:3119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3119", "name": "gastrointestinal system cancer", "description": "An organ system cancer located_in gastrointestinal tract that is manifested in organs of the gastrointestinal system." }, "synonyms": [ { "id": "DOID:3119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3119", "name": "GI tumor", "description": "" }, { "id": "DOID:3119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3119", "name": "digestive system cancer", "description": "" }, { "id": "DOID:3119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3119", "name": "gastrointestinal tract cancer", "description": "" } ], "unlinked_id_list": [ "DOID:10154", "DOID:0080355", "DOID:0060119", "DOID:8858", "DOID:4907", "DOID:5672" ], "evidence": [ { "id": "3119", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3119" } ] }, { "disease_id": "DOID:3571", "recommended_name": { "id": "DOID:3571", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3571", "name": "liver 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"https://disease-ontology.org/term/DOID:3571", "name": "malignant neoplasm of liver", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3571", "name": "malignant neoplasm of liver, primary", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3571", "name": "malignant tumor of liver", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3571", "name": "neoplasm of liver", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3571", "name": "non-resectable primary hepatic malignant neoplasm", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3571", "name": "primary liver cancer", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3571", "name": "primary malignant neoplasm of liver", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3571", "name": "resectable malignant neoplasm of the liver", "description": "" }, { "id": "DOID:3571", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3571", "name": "malignant neoplasm of liver, not specified as primary or secondary", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "3571", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3571" } ] }, { "disease_id": "DOID:437", "recommended_name": { "id": "DOID:437", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:437", "name": "myasthenia gravis", "description": "An autoimmune disease of the nervous system that has_material_basis_in antibodies to acetylcholine receptors at the neuromuscular junction, has_symptom ptosis, has_symptom diplopia, has_symptom dysphagia, has_symptom dysarthria, has_symptom muscle weakness and has_symptom shortness of breath." }, "synonyms": [ { "id": "MONDO:0009688", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009688", "name": "myasthenia gravis", "description": "Myasthenia gravis (MG) is a rare, clinically heterogeneous, autoimmune disorder of the neuromuscular junction characterized by fatigable weakness of voluntary muscles." }, { "id": "MONDO:0009688", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009688", "name": "acquired myasthenia", "description": "" }, { "id": "MONDO:0009688", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009688", "name": "autoimmune myasthenia gravis", "description": "" }, { "id": "MONDO:0009688", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009688", "name": "myasthenia gravis", "description": "" }, { "id": "MONDO:0009688", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009688", "name": "MG", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "437", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:437" } ] }, { "disease_id": "DOID:684", "recommended_name": { "id": "DOID:684", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver." }, "synonyms": [ { "id": "DOID:684", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:684", "name": "Hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma", "description": "A malignant tumor that arises from hepatocytes. Hepatocellular carcinoma is relatively rare in the United States but very common in all African countries south of the Sahara and in Southeast Asia. Most cases are seen in patients over the age of 50 years, but this tumor can also occur in younger individuals and even in children. Hepatocellular carcinoma is more common in males than females and is associated with hepatitis B, hepatitis C, chronic alcohol abuse and cirrhosis. Serum elevation of alpha-fetoprotein occurs in a large percentage of patients with hepatocellular carcinoma. Grossly, hepatocellular carcinoma may present as a single mass, as multiple nodules, or as diffuse liver involvement. Microscopically, there is a wide range of differentiation from tumor to tumor (well differentiated to poorly differentiated tumors). Hepatocellular carcinomas quickly metastasize to regional lymph nodes and lung. The overall median survival of untreated liver cell carcinoma is about 4 months. The most effective treatment of hepatocellular carcinoma is complete resection of the tumor. Lately, an increasing number of tumors have been treated with liver transplantation." }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "HCC", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "cancer, hepatocellular", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of liver", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of the liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma, hepatocellular, malignant", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatoblastoma, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular adenocarcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular cancer", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular cancer, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma, childhood type, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver cell cancer (hepatocellular carcinoma)", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver cell carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "primary carcinoma of liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "primary carcinoma of the liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "adult hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "adult primary hepatocellular carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma", "description": "A malignant tumor that arises from hepatocytes. Hepatocellular carcinoma is relatively rare in the United States but very common in all African countries south of the Sahara and in Southeast Asia. Most cases are seen in patients over the age of 50 years, but this tumor can also occur in younger individuals and even in children. Hepatocellular carcinoma is more common in males than females and is associated with hepatitis B, hepatitis C, chronic alcohol abuse and cirrhosis. Serum elevation of alpha-fetoprotein occurs in a large percentage of patients with hepatocellular carcinoma. Grossly, hepatocellular carcinoma may present as a single mass, as multiple nodules, or as diffuse liver involvement. Microscopically, there is a wide range of differentiation from tumor to tumor (well differentiated to poorly differentiated tumors). Hepatocellular carcinomas quickly metastasize to regional lymph nodes and lung. The overall median survival of untreated liver cell carcinoma is about 4 months. The most effective treatment of hepatocellular carcinoma is complete resection of the tumor. Lately, an increasing number of tumors have been treated with liver transplantation." }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "HCC", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "cancer, hepatocellular", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of liver", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of the liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma, hepatocellular, malignant", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatoblastoma, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular adenocarcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular cancer", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular cancer, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma, childhood type, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver cell cancer (hepatocellular carcinoma)", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver cell carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "primary carcinoma of liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "primary carcinoma of the liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "adult hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "adult primary hepatocellular carcinoma", "description": "" }, { "id": "MIM:114550", "resource": "MIM", "url": "https://www.omim.org/entry/114550", "name": "Hepatocellular carcinoma", "description": "Hepatocellular carcinoma" } ], "unlinked_id_list": [], "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ] }, { "disease_id": "DOID:8645", "recommended_name": { "id": "DOID:8645", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8645", "name": "subacute delirium", "description": "" }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "8645", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8645" } ] }, { "disease_id": "DOID:9256", "recommended_name": { "id": "DOID:9256", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum." }, "synonyms": [ { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer", "description": "A primary or metastatic malignant neoplasm that affects the colon or rectum. Representative examples include carcinoma, lymphoma, and sarcoma." }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "cancer of colorectum", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "cancer of large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "cancer of large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "cancer of the large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colon cancer, advanced, somatic", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colon cancer, somatic", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer with chromosomal instability, somatic", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer, somatic", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectum cancer", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant colorectal neoplasm", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant colorectal tumor", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant colorectal tumour", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant colorectum neoplasm", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large bowel neoplasm", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large bowel tumor", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large bowel tumour", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large intestine neoplasm", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large intestine tumor", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large intestine tumour", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of colorectum", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of the large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of the large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumor of large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumor of large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumor of the large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumor of the large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumour of large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumour of large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumour of the large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumour of the large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "CRC", "description": "" }, { "id": "MIM:114500", "resource": "MIM", "url": "https://www.omim.org/entry/114500", "name": "Colorectal cancer", "description": "Colorectal cancer" } ], "unlinked_id_list": [], "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ] }, { "disease_id": "DOID:9470", "recommended_name": { "id": "DOID:9470", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9470", "name": "bacterial meningitis", "description": "A meningitis that has_material_basis_in a bacterial infection." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "9470", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9470" } ] }, { "disease_id": "DOID:9744", "recommended_name": { "id": "DOID:9744", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9744", "name": "type 1 diabetes mellitus", "description": "A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production." }, "synonyms": [ { "id": "DOID:9744", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9744", "name": "IDDM", "description": "" }, { "id": "DOID:9744", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9744", "name": "insulin-dependent diabetes mellitus", "description": "" }, { "id": "DOID:9744", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9744", "name": "type I diabetes mellitus", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "type 1 diabetes mellitus", "description": "A chronic condition characterized by minimal or absent production of insulin by the pancreas." }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "IDDM", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "T1D", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "T1DM", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "diabetes mellitis type 1", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "diabetes mellitis type I", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "immune mediated diabetes", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "insulin dependent diabetes", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "juvenile diabetes", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "type 1 diabetes", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "type I diabetes", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "type I diabetes mellitus", "description": "" }, { "id": "MIM:222100", "resource": "MIM", "url": 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"database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG4757", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG4757", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LHWPLYN", "url": "https://omabrowser.org/oma/group/LHWPLYN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9Y141", "url": "https://www.orthodb.org/?gene=Q9Y141", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11559", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11559", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00135", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00135", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DME-2022377", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-2022377", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-211945", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-211945", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-5578768", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-5578768", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-8964038", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8964038", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DME-9749641", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9749641", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001262469", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001262469", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9Y141", "url": "https://www.uniprot.org/uniprotkb/Q9Y141", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9Y141-1", "url": "https://www.uniprot.org/uniprotkb/Q9Y141-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLMLFVVELLVLLASSSVLSIEVDTELGRVRGANLTSRLGVNFHAFRGIRYAEPPLGDLRFVNPQPVKPWSPKIFDASEDGPMCPQPWDNMTDVSEDCLRLNVYTKDLKGRRPVIVFLHPGGFYVFSGQSKYLAGPEHFMDRDCVLVSLNYRLGSLGFLATGSKEAPGNAGLKDQVLALRWIQQHIQRFGGDPDSVTLLGYSAGSISVALHMLSPMSRGLFHRGICMSAAPYGPVKYKDNDLQLAKRQAGLLKCPQESIGEMVECMRRKPYLDYVSTYNGMFEFGWNPVLNWRIVVEKDFGQERYLIESPFKTARRGDFHKVALITGITEFEFLSGAFFDLRNESIVNRYNRDWEHYASIALLLEQNSTQSRAASRVFREKYMPESLDKLEYPKSLKGMGELLSDALIGVSFHRFLQLMSPHTPIYTYLFRYKGRYTFLKNPDNQQTIGPVHHDELIYLFHVGLLIPLLKREDPENFMIELLTRMWIEFAQKGDPHNKNDEYLKGLNWPLYNAQDKGYLEIGNNLTAKSGGFFLNRYQIWEDLFPLSSFH", "length": 550, "header": "tr|Q9Y141-1|Q9Y141_DROME Isoform 1 of Carboxylic ester hydrolase OS=Drosophila melanogaster OX=7227 GN=GH05741 PE=3 SV=1 CANONICAL=Q9Y141-1" }, "isoforms": [ { "isoform_ac": "Q9Y141-1", "url": "https://www.uniprot.org/uniprotkb/Q9Y141/entry#Q9Y141-1", "sequence": { "sequence": "MLMLFVVELLVLLASSSVLSIEVDTELGRVRGANLTSRLGVNFHAFRGIRYAEPPLGDLRFVNPQPVKPWSPKIFDASEDGPMCPQPWDNMTDVSEDCLRLNVYTKDLKGRRPVIVFLHPGGFYVFSGQSKYLAGPEHFMDRDCVLVSLNYRLGSLGFLATGSKEAPGNAGLKDQVLALRWIQQHIQRFGGDPDSVTLLGYSAGSISVALHMLSPMSRGLFHRGICMSAAPYGPVKYKDNDLQLAKRQAGLLKCPQESIGEMVECMRRKPYLDYVSTYNGMFEFGWNPVLNWRIVVEKDFGQERYLIESPFKTARRGDFHKVALITGITEFEFLSGAFFDLRNESIVNRYNRDWEHYASIALLLEQNSTQSRAASRVFREKYMPESLDKLEYPKSLKGMGELLSDALIGVSFHRFLQLMSPHTPIYTYLFRYKGRYTFLKNPDNQQTIGPVHHDELIYLFHVGLLIPLLKREDPENFMIELLTRMWIEFAQKGDPHNKNDEYLKGLNWPLYNAQDKGYLEIGNNLTAKSGGFFLNRYQIWEDLFPLSSFH", "length": 550, "header": "tr|Q9Y141-1|Q9Y141_DROME Isoform 1 of Carboxylic ester hydrolase OS=Drosophila melanogaster OX=7227 GN=GH05741 PE=3 SV=1 CANONICAL=Q9Y141-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "33925313", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33925313" }, { "id": "Q9Y141", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9Y141" } ], "filter_code": "00000000000000000000.0000000.00000001000000.1000000.0100000000.110100100001111011.10000.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_reported_with_glycan" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9Y141", "url": "https://www.uniprot.org/uniprotkb/Q9Y141" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9Y141", "url": "https://www.uniprot.org/uniprotkb/Q9Y141" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9Y141", "url": "https://www.uniprot.org/uniprotkb/Q9Y141" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9Y141", "url": "https://www.uniprot.org/uniprotkb/Q9Y141" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9Y141", "url": "https://www.uniprot.org/uniprotkb/Q9Y141" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9Y141", "url": "https://www.uniprot.org/uniprotkb/Q9Y141" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9Y141", "url": "https://www.uniprot.org/uniprotkb/Q9Y141" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9Y141", "url": "https://www.uniprot.org/uniprotkb/Q9Y141" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9Y141", "url": "https://www.uniprot.org/uniprotkb/Q9Y141" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9Y141", "url": "https://www.uniprot.org/uniprotkb/Q9Y141" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9Y141", "url": "https://www.uniprot.org/uniprotkb/Q9Y141" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] }, { "title": "Drosophila O-GlcNAcase Mutants Reveal an Expanded Glycoproteome and Novel Growth and Longevity Phenotypes.", "journal": "Cells", "date": "2021", "authors": "Akan I, Halim A, Vakhrushev SY, Clausen H, Hanover JA", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9Y141", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9Y141" } ], "reference": [ { "type": "PubMed", "id": "33925313", "url": "https://glygen.org/publication/PubMed/33925313" } ] } ], "pathway": [ { "id": "dme:Dmel_CG4757", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG4757", "resource": "KEGG Pathway" }, { "id": "R-DME-2022377", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-2022377", "resource": "Reactome", "description": "Metabolism of Angiotensinogen to Angiotensins" }, { "id": "R-DME-211945", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-211945", "resource": "Reactome", "description": "Phase I - Functionalization of compounds" }, { "id": "R-DME-5578768", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-5578768", "resource": "Reactome", "description": "Physiological factors" }, { "id": "R-DME-8964038", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8964038", "resource": "Reactome", "description": "LDL clearance" }, { "id": "R-DME-9749641", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9749641", "resource": "Reactome", "description": "Aspirin ADME" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0B4K6L1-1", "protein_name": "Carboxylic ester hydrolase", "gene_name": "alpha-Est10", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRRYWVSLLRHFSLIPNKSVPKVFTNGDFIQQVISFKYEQRKLSTAIYSVIKTKSGPVRGVKRNTIWGGSYFSFEKIPFAKPPVGDLRFKAPEAVEPWDQELDCTSPADKPLQTHMFFRKYAGSEDCLYLNVYVKDLQPDKLRPVMVWIYGGGYQVGEASRDMYSPDFFMSKDVVIVTVAYRLGALGFLSLDDPQLNVPGNAGLKDQIMALRWVQQNIEAFGGDSNNITLFGESAGGASTHFLALSPQTEGLIHKAIVMSGSVLCPWTQPPRNNWAYRLAQKLGYTGDNKDKAIFEFLRSMSGGEIVKATATVLSNDEKHHRILFAFGPVVEPYTTEHTVVAKQPHELMQNSWSHRIPMMFGGTSFEGLLFYPEVSRRPATLDEVGNCKNLLPSDLGLNLDPKLRENYGLQLKKAYFGDEPCNQANMMKFLELCSYREFWHPIYRAALNRVRQSSAPTYLYRFDHDSKLCNAIRIVLCGHQMRGVCHGDDLCYIFHSMLSHQSAPDSPEHKVITGMVDVWTSFAAHGDPNCESIKSLKFAPIENVTNFKCLNIGDQFEVMALPELQKIEPVWNSFYAPNKL", "length": 581 }, "evidence": [ { "id": "MGI:3648919", "url": "https://alliancegenome.org/gene/MGI:3648919#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A0A0B4K6V8-1", "protein_name": "carboxylesterase", "gene_name": "alpha-Est5", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MMSKESSLETCELTLPVGQIKGVKRLSLYDDPYFSFEKIPFAKPPLGELRFRAPVPADPWSGVLDCTHYAEKPTQRGLLTREIEGGEDCLYLNVYSKQLKSEKPLPVMVYIYGGAFTVGEATRELYGPDYFMTKDVVLVTLNYRVDCLGFLSLKDPSLKVPGNAGLKDQVLALKWVKQYISNFNGDDSNITVFGESAGGCSTHFMMCTEQTRGLFHKAIPMSGTVHNYWANNPAEDFAFRLAQQNGFTGENDDAKVLEYLQGVPARDLVNHNLLTPEHRRNGLLFAFGPTVEAYVGEDCVVPKPPVEMARDAWSNNFPVMLGGTSFEGLFMYPAVSANLKALDSLSQDPTRLVPVDVRTVSSEKENLEYSQRLMKAYFGYSPPSSELLLNMLDFYSYKIFWHGFNRTFNARLTYAKAPTYYYRFDFDSPNFNFYRAKFCGDKIKTGVAHADDLSYLFRNAGSWKLDKTSAEYRTIERMIGIWTAFAATSNPNCPEIGHLEWKPSTKNDPKRVINISSDVTIIDLPEYEKLQIWDNLYKPNQLI", "length": 543 }, "evidence": [ { "id": "HGNC:1863", "url": "https://alliancegenome.org/gene/HGNC:1863#orthology", "database": "AGR" }, { "id": "MGI:2148202", "url": "https://alliancegenome.org/gene/MGI:2148202#orthology", "database": "AGR" }, { "id": "MGI:3779470", "url": "https://alliancegenome.org/gene/MGI:3779470#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A0A8M9PZ17-1", "protein_name": "Uncharacterized protein ces2b", "gene_name": "ces2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAMRESAVLSLCILIAVTLQNSVKAEDGPILQTNSGALKGLQMKARGKDTVIHSYLGIPFAKPPVGPLRLAPPQPAEKWEGVRDATKQPLMCLQDRQLVEDLVANLSAKVDMVDSSEDCLYLNVYTPSKPGRNDKLPVMVWIHGGGFTTCSASLFDGHVLAAYQDVVVVVIQYRLGLLGFFSTGDENAPGNYGLLDQVAALQWVQENIHSFGGDPGSVTIFGESAGGISVSLHVLSPLSANLFHRAIAESGTAAMEAIMNVNPLPIAQAIGNASGCDISSTKKIVDCLMQKSEVEILKITMENPLFRFGVTIDGQFLPRPAAELFQSQQFNKVPLMTGVTDDEIGFVLPNYLLPPDWINGLDLESILPLLTVFNPALQDQSVLELLLNEYLGTSPDRIRIRDGFREMLGDFMFNIPARQTASYHRDAGAPVYVYEFRHPPSVLQRKRPSFSGSDHGDEIVFVFGYCFSEGPIGMAENLSDEEDELCRTTMAYWGNFAHTGNPNGPGLTSWPEFGDEAEYLSIGLDPKASTDLKGKHFTFVTQTFPRILSERKEGPVVNTKLGSLRGSYMMAKGKDSVISSYFAIPFAKSPVGPLRLTPPQPADAWQGVRDATKQPPMCLQPKEVMVDLLATMPLKTEFPEVSEDCLYLNIYTPSKPGDNKKLPVMVWIHGGGLAFGSASIFDAHALAAYQDIVVVMVQYRLGLLGFFSTGDEHAPGNYGLLDQVAALQWVQENIHSFGGDPGSVTVFGESAGGVSASLLVLSPLSANLFHRAIAESGTAAMNAIMSPDPLSTARSLGNVSGCDISSTKKIVDCVMQMTEEDILKIAREQVLLRFGVTVDGQFLPKSVDELLQSQEFSKVPLMTGVTDDDGGFTLPEFIAPPGWRDGMTKDQIMPFLPTYNYDLQDPGLAEIVLKEYLGATTDKIKIRDGFREIVGDFFFNLPARKLANYHRDTGAPVYMYEFQHPAYIFQNKRPSFVGCDHGDELLFVFGYCFGNGHIKVEGELSKEEQELCKTTMAYWGNFARTGNPNGPGLVEWPKYGAEAEYLGIGLEQKSSKNFKGNHFHFMIEKLPQIIKEWKEGPVVETKLGSLRGAFLTVKGKDTIVNSYLGVPFAKPPVGPLRLARPQAAEKWQGVRDATKQPRMCLQERQMTVTELEFLSMDVEVPEVSEDCLYLNIYTPVKPGQGDKKLPVMVWIHGGGLSLGSASMYDGSVLAAYQDVVVVLIQYRLGLLGFLSTGDEHAPGNYGFLDQVAALQWVQENIHSFGGDPGSVTIFGESAGGISVSTLILSPLASGLFHRAIAESGTAFWDGLVMADPFQRAQTAAKQCNCDSSSSAKIVDCIMHWSEEEALECAKKFQMMHFSVAVDSYFLPKPIEEIVEKQEFSKVPLINGINNDEFGFLLAEYFLGPEWMNGLKREQIAEALTLTYPDPKDRWIIDLVAKEYLGDTHDPIEIREVYREMMGDVLFNIPALQLAKHHSGTGAPVYLYELQHPPSFLQKKRPSFVGVDHADDLYFIQGTCFAKAHLRISAPFTEEENELCRTVMAYWGNFAHTGSPNGPGLTHWPEYENENEYLAIGLQQKPGKNLKHKHYEFMTKTLPELIRQGKTKHSEL", "length": 1611 }, "evidence": [ { "id": "MGI:2385905", "url": "https://alliancegenome.org/gene/MGI:2385905#orthology", "database": "AGR" }, { "id": "MGI:1919611", "url": "https://alliancegenome.org/gene/MGI:1919611#orthology", "database": "AGR" }, { "id": "MGI:3648740", "url": "https://alliancegenome.org/gene/MGI:3648740#orthology", "database": "AGR" }, { "id": "MGI:3644960", "url": "https://alliancegenome.org/gene/MGI:3644960#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABK0L778-1", "protein_name": "Carboxylic ester hydrolase", "gene_name": "Ces1e", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCLYALILVFLAAFTAGGHPSSLPVVDTLQGKVLGKYVSLEGFTQPVAVFLGVPFAKPPLGSLRFAPPQPAEPWSFVKNTTSYPPMCSQDPVAGQIVNDLLTNREENISLQFSEDCLYLNIYTPADLTKRDRLPVMVWIHGGGLVLGGASTYDGLALSTHENVVVVVIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALHWVQDNIDNFGGDPGSVTIFGESAGGESVSVLVLSPLAKNLFHKAISESGVALTAGLVKKNTRPLAEKIAVVSGCKSTTSAAMVHCLRQKTEEELLETTLKLNLFSLDLHGDSRQSYPFVPTVLDGVVLPKMPEEILAEKDFNTVPYIVGINKQEFGWILPTMMNYPPSDMKLDPMTATSLLKKSSFLLNLPEEAIPVAVEKYLRHTDDPDRNKDQLLELIGDVIFGVPSVIVSRGHRDAGARTYMYEFQYRPSFSSKMKPSTVVGDHGDEIYSVFGAPILRGGTSKEEINLSKMMMKFWANFARNGNPNGQGLPHWPEYDQKEGYLQIGATTQQAQKLKEKEVAFWSELLAMKPLHAGHTEL", "length": 561 }, "evidence": [ { "id": "MGI:95432", "url": "https://alliancegenome.org/gene/MGI:95432#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0M2N6-1", "protein_name": "Carboxylic ester hydrolase", "gene_name": "Ces1f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSCEGIQHLPSSAPGEGLSQDSWTGSQNVGRTLHSPSLWIRVRNSTDWSTCPCKMCLSFLFLVSLATCVVYGNPSSPPVVDTTKGKVLGKYVSLEGVTQSVAVFLGVPFAKPPLGSLRFAPPQPAEPWSFVKNTTTYPPMCSQDAAKGQRMNDLLTNRKEKIHLEFSEDCLYLNIYTPADFTKNSRLPVMVWIHGGGMTLGGASTYDGRVLSAYENVVVVAIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALHWVQDNIANFGGDPGSVTIFGESAGGFSVSVLVLSPLTKNLFHRAISESGVVFLPGLLTKDVRPAAKQIADMAGCETTTSAIIVHCLRQKTEEELLEIMKKMNLIKLSSQRDNKESYHFLSTVVDNVVLPKDPKEILAEKNFNTVPYIVGINKQECGWLLPTMMGFVPADVELDKKMAITLLEKFASLYGIPEDIIPVAIEKYRKGSDDSIKIRDGILAFIGDVSFSIPSVMVSRDHRDAGAPTYMYEYQYYPSFSSPQRPKHVVGDHADDLYSVFGAPILRDGASEEEIKLSKMVMKFWANFARNGNPNGRGLPHWPQYDQKEEYLQIGATTQQSQRLKAEEVAFWTQLLAKRQPQPHHNEL", "length": 615 }, "evidence": [ { "id": "HGNC:1863", "url": "https://alliancegenome.org/gene/HGNC:1863#orthology", "database": "AGR" }, { "id": "MGI:1922954", "url": "https://alliancegenome.org/gene/MGI:1922954#orthology", "database": "AGR" }, { "id": "MGI:2142687", "url": "https://alliancegenome.org/gene/MGI:2142687#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A1ZA97-1", "protein_name": "Carboxylic ester hydrolase", "gene_name": "Jhedup", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLFAGFGVLLFVAVAVGDSLDVCLEDMGCMRGTLMPGYQSGEFEAFMGIPFAQPPVGPLRLKNPVPNEPWEGVLDAGAAKDSCIQRSYFAKEWGLMGVEDCLYLNVYRPKNRAEDKLPVMVYIHGGGFFSGSAHPMASGPEYLMDTNKVVMVTMNYRLGPFGFLSTGDEHMPGNFGFKDQRLALQWIQKHIATFGGDPKKVTVLGHSAGGISAHLHMISPNSKGLFQNSMSLTGTMFLSAMKILKDPLSQARRLGKELAIDQAESLSSQDLAEALRNVCPKKLLVSVDSLKVWDNMPHLTTLPVLEAPSPDAFLVEDPLDAHRAGRINQMPWILSLSSRAGEGSLFIMRAFINPKLRAEFNENFLEHMALLLNLPEGTPVQMVSEILDAYDFKGDSLNNDTMLKLAEISGDFNFYYPIYETISSYVTYANLEENPLFIYIFEFAGLNSITKFFAGTTDDYGLGAVHMDDGLHTIRIPVSFDDFPKDSEDAKVIQRMSSLMTDFAKTGVFHEESICKVSDFKEQGMCNYLHFGGNKEKYLEDIRNSITLTAFPIWKKLFA", "length": 559 }, "evidence": [ { "id": "HGNC:108", "url": "https://alliancegenome.org/gene/HGNC:108#orthology", "database": "AGR" }, { "id": "HGNC:1863", "url": "https://alliancegenome.org/gene/HGNC:1863#orthology", "database": "AGR" }, { "id": "MGI:102773", "url": "https://alliancegenome.org/gene/MGI:102773#orthology", "database": "AGR" }, { "id": "MGI:3644960", "url": "https://alliancegenome.org/gene/MGI:3644960#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A1ZA98-1", "protein_name": "Carboxylic ester hydrolase", "gene_name": "Jhe", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MIQQRMLQLLLLGQLLAGPGPFCAALATVDQLTVCPPSVGCLKGTNLQGYQSERFEAFMGIPYALPPIGDLRFSNPKVMPKLLGMYDASAPKMDCIQKNYLLPTPVVYGDEDCLYLNVYRPEIRKSALPVMVYIHGGGFFGGSAGPGVTGPEYFMDSGEVILVTMAYRLGPFGFLSTQDAVMSGNFGLKDQNLALRWVQRNIRFFGGDPQRVTIFGQSAGGVAAHMHLLSPRSHGLFHRVISMSGTANVPFAIAEQPLEQARLLAEFADVPDARNLSTVKLTKALRRINATKLLNAGDGLKYWDVDHMTNFRPVVEEGLEVDAFLNAHPMDMLAQGMPTSIPLLLGTVPGEGAVRVVNILGNETLRQSFNLRFDELLQELLEFPASFSQDRREKMMDLLVEVYFQGQHEVNELTVQGFMNLISDRGFKQPLYNTIHKNVCHTPNPVYLYSFNYQGPLSYASAYTSANVTGKYGVVHCDDLLYLFRSPLLFPDFQRNSTEAKVIHSFVDYFVHFAKFGKPRNSESLTPCSIEVLQSRPDGICDYHEFANAPDAYQGFEVHVASEFQTDRVNLWSHILNEK", "length": 579 }, "evidence": [ { "id": "MGI:3779470", "url": "https://alliancegenome.org/gene/MGI:3779470#orthology", "database": "AGR" }, { "id": "MGI:88378", "url": "https://alliancegenome.org/gene/MGI:88378#orthology", "database": "AGR" }, { "id": "MGI:95420", "url": "https://alliancegenome.org/gene/MGI:95420#orthology", "database": "AGR" }, { "id": "MGI:2385905", "url": "https://alliancegenome.org/gene/MGI:2385905#orthology", "database": "AGR" }, { "id": "MGI:2384581", "url": "https://alliancegenome.org/gene/MGI:2384581#orthology", "database": "AGR" }, { "id": "MGI:1915185", "url": "https://alliancegenome.org/gene/MGI:1915185#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "D3Z298-1", "protein_name": "Carboxylic ester hydrolase", "gene_name": "Ces1h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCLYALILLSLSAMAWGGYPSSPPVVNTTHGKVLGKYISLEGFTQPVAVFLGVPFAKPPLGSLRFAPPQPPEPWSFVKNATSYPPMCSQDAVLGQMVNDLIINNKEKIRLRFSEDCLYLNVYTPVDLMKNTNRLPVMVWIHGGGLVVGGASAYDGRTLSAHENVVVVTIQYRLAIWGFFSTGDEHSRGNWGHLDQLAALHWIQDNIANFGGDPGSVTIFGQSAGGESVSVLVLSPLAKNLFHRAISQSGVVFTSGLFMEDASSVTEQIAVTAGCKTTTSAVIVHCLRQKTEEELLEIMQKMNLFKLDAQENTKKNYPFLPTVLDGVVLPKAPEAILAEKNFNTVPYIVGINKQEFGWTLPMIMEFPPTDVKLDKKVISLFLRKLAYFFNIPEDGIPVAIEKYSKGTDDPIQNRVWLLQLIGDVMFGIPSVIVSRGHRDAGAPTYMYEFQSRPSFSSELKPKTVTGDHGDEVYSVFGAPILREGSSEEEINLSKMMMKFWANFARNGNPNGQGLPHWPEYNQKKGYLQIGATTQQAQGLKDKEVSLWTELRAKKPPQTGHTEL", "length": 562 }, "evidence": [ { "id": "HGNC:1863", "url": "https://alliancegenome.org/gene/HGNC:1863#orthology", "database": "AGR" }, { "id": "MGI:1922954", "url": "https://alliancegenome.org/gene/MGI:1922954#orthology", "database": "AGR" }, { "id": "FB:FBgn0027584", "url": "https://alliancegenome.org/gene/FB:FBgn0027584#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z5G7-1", "protein_name": "Carboxylic ester hydrolase", "gene_name": "Ces1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWLHALVWASLALCPIWGHSPSSPVVDTTQGKILGKYTSLEGFEHPVAVFLGVPFAKPPLGSLRFAPPEPAEPWSFVKNATSYPPMCSQDAVAVQLLSDMLSTKKESIPPLFSEDCLYLNIYSPADLTKSSLLPVMVWIHGGGLMTGGASLYNGLALSAHENVVVVTIQYRLGIWGLFSTGDEHSRGNWAHLDQLAALRWVQDNIANFGGNPDSVTVFGSSAGGVSVSVLVLSPLAKNLFHRAISESSVVLENIVITLDLVACDLSQMIATVSGCNDTSSTAMVQCLRQKTENELLEITVKLEVTKVGGAASAKKDNTSMSTVIDGVVLPKAPEEILAEKSFSTVPYIVGFNKQEFGWIIPTMLGDLLSEGKMNEETASLLLRRFHSDLNISESLIPAVIEKYLRGTDDPAKKRDLLLDMFSDVFFGIPAVLLSRSLRDAGVSTYMYEFRYRPSFVSDKRPQTVEGDHGDEIFSVFGIPLLKEGTSEEETNLSKMVMKFWANFARNGNPNGEGLPHWPEYDEKEGYLQIGATTQQAQRLKAEEVAFWTELLAKNPPETDPTEHREHK", "length": 567 }, "evidence": [ { "id": "HGNC:1863", "url": "https://alliancegenome.org/gene/HGNC:1863#orthology", "database": "AGR" }, { "id": "MGI:3779470", "url": "https://alliancegenome.org/gene/MGI:3779470#orthology", "database": "AGR" }, { "id": "FB:FBgn0027584", "url": "https://alliancegenome.org/gene/FB:FBgn0027584#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D4AA05-1", "protein_name": "Carboxylic ester hydrolase", "gene_name": "Ces1a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIRPLDCTWMGVVTRPHNVRRVMQSPSEEHRDPVTGPQSNWPSTMWLFALALTSLNTYMAFGHPSSPPVVDTLQGKVLGKYISLEGFTQPVAVFLGVPFAKPPLGSLRFAPPQPAESWSFVKNATSYPPMCSQITGVGPVLSEVFTNQLENVPLEYSEDCLYLNIYSPTDLTSKDRLPVMVWVHGGGLLSGGASTFDGLALSTHEKVVVVVIQYRLGIWGFLSTGDEHSRGNWGHFDQVAALQWVQNNIVNFGGDPNSVTLFGESAGGESVSVLVLSPLTKNLFHRAISESGVALTPCLFRENTRLAAEQVAIATGCAATTSADIVRCLREKTEEELLATTLKMKFFALDLHGDPRESYPFLTTVIDGVLLPKAPEEILSEKNFNTVPYIVGINKQEFGWFIPTMMGYPLSESKLDQKTATSLLWKSYPLTNISKELTPVATEKYLGGSDCPDKKKDLFLDMMGDVLFAVPSVIVARYHRDARATTYVYEFKYHPSFVSDMRPKTVIADHGDEVYSVWGTPFLKEGASEEEINLSTMMMKFWGNFARNGNPNGEGLPHWPEYDEKESYLQIGTTIQQAQKLKYKEVAFWTGLRGMEVEEATEEDTQK", "length": 607 }, "evidence": [ { "id": "HGNC:1863", "url": "https://alliancegenome.org/gene/HGNC:1863#orthology", "database": "AGR" }, { "id": "MGI:3648919", "url": "https://alliancegenome.org/gene/MGI:3648919#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AE76-1", "protein_name": "Carboxylic ester hydrolase", "gene_name": "Ces4a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEAGWSMKWTLDLSLTLWLVVQTALGALHTKEPLLITKHGILQGKQVHVGDTPIRVFLGVPFSQPPVGTRRFAPPEPPLPWNGIRDATTYPPSCLQESWGQITSMYLNTRKQYEWLHFSEDCLYLNVYAPVLAPGDPLLPVMVWFPGGAFLVGSASTYEGSELAARGKVVLVFLQYRLGILGFFSTGNSHARGNWGLLDQIAALRWVQENIEAFGGDPDSVTLFGQSAGAMSVSGLLMSPLAQGLFHQAISQSGTAVLKTFITHDPLKSAKKIAHLAGCDHNSTKIMVKCLKALPAEKVMLVSKKMTFFRANSHKDPKDIVWFLSPVVDGLVFPEDPVVLLTRGQVKPVPYLLGVNSAEFEWSLPFLMKLQLNQRIMNKNYITKLLWSCSILLNITEEQIPLVAREYLSDAISHHDWKMFRNHLIDLVGDATFVYATLQAARYHRDAGSPVYLYEFKHHAPGIIVKPRSDGADHGDELSYLFGSPFSKGSSRGEEKEFSLQMMKYWANFAHTGDPNDRELPYWPRFDKEEKYLQLDFDTRVGVKLREKQMTFWRRLRQPQKP", "length": 563 }, "evidence": [ { "id": "MGI:2384581", "url": "https://alliancegenome.org/gene/MGI:2384581#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9PV38-1", "protein_name": "Carboxylic ester hydrolase", "gene_name": "Ces2g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRNQMHSWLDAVFFGLLLLLGHVQGHDSPETSPIRSTHSGQVQGRLIHVKDTKAGVHTFLGIPFAKPPVGPLRFAPPEAPEPWSGVRDGTSQPAICPQNVTMNMEGLKELKLTLPPVSMSEDCLYLNIYTPAHAQEGSNLPVMVWIHGGALTVGMASMYDGSVLAATEDVVVVAIQYRLGVLGFFSTGDEHARGNWGFLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGISVSSHVVSPMSKGLFHRAIMESGVALLPGTIFSFSEVVYQTVAKLSGCEAMDSEALVRCLRGKSEEEILAISKNFQMIPGVVDGEFLPKHPQELLASADFHPVPSIIGFNNDEYGWIVPKVIGSTQTIKGITRENLQAVLKDTAPQMMLPPECSDLLMEEYMEDIEDPKTLQIQFTEMMEDFMFVIPSLQVAYFQRSHAPVYFYEFQHQSSFLKDVRPPHVNADHGDEVPFVFGSFFWGMKLNLTEEEKLLNRRMMKYWANFARHGNPNSESLPYWPVFDHDEQYLQLNIQPAVGQFQKARKLQFWTKTLPRKIEELKRSQNVHKEL", "length": 560 }, "evidence": [ { "id": "MGI:1919611", "url": "https://alliancegenome.org/gene/MGI:1919611#orthology", "database": "AGR" }, { "id": "FB:FBgn0027584", "url": "https://alliancegenome.org/gene/FB:FBgn0027584#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PYP1-1", "protein_name": "Carboxylic ester hydrolase", "gene_name": "Ces1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWLFALALASLNTCMALGHLSSPPVVDTLQGKVMGKYISLEGSAQPVAVFLGVPFAKPPLGPLRFAPPQPAETWSSVKNTTSYPPMCSQITGVGPVLSDVFTNQLENVPLEYSEDCLYLNIYSPTDLTSKDRLPVMVWVHGGGLLSGGASTFDGLALSTHENVVIVVIQYRLGIWGFLSTGDEHSRGNWGHLDQVAALQWVQNNIANFGGDPSSVTLFGESAGGESVSVLVLSPLTKNLFQRAISESGVALTPCLFRETTRRAAEQVAIATGCVATTSADIVHCLREKTEEELLATTLKMKFFALDLLGDPRESYPFLTTVIDGVVLPKAPEEILAEKSFNTVPYIVGINKQEFGWFIPMMMGYPLSEGKLDQKSATSLLWKSYPLTNISKELTPVATEKYLGGSDCPDKKKDLFLDMMGDVLFAVPSVIVARYHRDAGAPTYMYEFKYHPSFVSDMRPKTVIADHGDEVYSVWGTPFLKEGASEEEINLSTMMMKFWGNFARNGNPNGEGLPHWPEYGEKESYLQIGATTQQAQRLKDKEVAFWTSLRAMEVGEATKGDTQR", "length": 563 }, "evidence": [ { "id": "HGNC:1863", "url": "https://alliancegenome.org/gene/HGNC:1863#orthology", "database": "AGR" }, { "id": "MGI:3648919", "url": "https://alliancegenome.org/gene/MGI:3648919#orthology", "database": "AGR" }, { "id": "FB:FBgn0027584", "url": "https://alliancegenome.org/gene/FB:FBgn0027584#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6Z9B9-1", "protein_name": "Carboxylic ester hydrolase", "gene_name": "Ces2h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRLEQIHARLTTATCGLLLLLRVQGQDSTSPIRTTHTGQILGSLIHMKDLDVGVHSFLGIPFAKPPVGPLRFAPPEPPEPWGGVRDGTSHPAMCLQDITAMNMQAFKLLKLTLPPFPMSEDCLYLNIYAPDHAHEGSNLPVMVWIHGGSLVIGMASMYDGSMLAAMENVVVVTIQYRLGVLGFFSTGDERARGNWGYLDQVAALRWLQQNIAYFGGNPDRVTIFGTSAGGTSVSSLVVSPMSQGLFRGAIMESGVALISSLISVSSDVVYQTVANLSGCEQVDSEALVNCLRGKSEEEIMAINKAFKIIPGIVDGIFLPRHPQELMASADFHPVPSIIGVNNDEYGWIIPSSMSMIDSKKGMDRQMVQAILQRRATQMMWPPEVSDLLMEEYMGDNEDPQFLQVQFKEMMKDFTFVIPALQVAQFQRSHAPVFFYEFQHRPSFFKDSKPSHVKADHGDEILFIFRSFWGGTQVDFTEEEELLSRRMMKYWANFARQRNPNSEGLPYWPMFDQDEQYLQLDTQPAVGRALKTRRLQFWTKTLPEKIQELKDIEDRHKEL", "length": 558 }, "evidence": [ { "id": "MGI:3648740", "url": "https://alliancegenome.org/gene/MGI:3648740#orthology", "database": "AGR" }, { "id": "FB:FBgn0027584", "url": "https://alliancegenome.org/gene/FB:FBgn0027584#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0R7R1-1", "protein_name": "Carboxylic ester hydrolase", "gene_name": "Cesl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCLRSLFLVSLATCVVCGNPSSPPVVDTMKGKVLGKYASLEGVTQSVAVFLGVPFAKPPLGSLRFAPPQPAEPWSFVKNTTTYPPMCSQDATKGQRMNDLLTNRKEKVHLQFSEDCLYLNIYTPADFTKDSRMPVMVWIHGGGLTQGGASTYDGQVLSAYENVVVVAIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALHWVQDNIANFGGDPGSVTIFGESAGGFSVSVLVLSPLSKNLYHRAISESGVVLITELFTKDVRPAAKQIADMAGCKTTTSAIIVHCLRQKTEEELLEIMEKMNLIKLSSQRDTKESYHFLSTVIDDVVLPKDPKEILAEKNFNTVPYIVGINKQECGWLLPTMMRFVPPDVKLDKKMAIMLLEKFASIYGIPEDIIPVAIEKYRKGSDDPIKIRDGILAFIGDALFCIPSVMVSRDHRDAGAPTYVYEYQYYPSFSSPQRPKDVVGDHADDVYSVFGAPILRDGASEEEIKLSKMVMKFWANFARNGNPNGRGLPHWPQYDQKEEYLQIGATTQQSQGLKAEEVAFWTQLLAKRQPQPHHNEL", "length": 561 }, "evidence": [ { "id": "HGNC:1863", "url": "https://alliancegenome.org/gene/HGNC:1863#orthology", "database": "AGR" }, { "id": "MGI:1922954", "url": "https://alliancegenome.org/gene/MGI:1922954#orthology", "database": "AGR" }, { "id": "MGI:2142687", "url": "https://alliancegenome.org/gene/MGI:2142687#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O00748-1", "protein_name": "Cocaine esterase", "gene_name": "CES2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRLHRLRARLSAVACGLLLLLVRGQGQDSASPIRTTHTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLIASSADVISTVVANLSACDQVDSEALVGCLRGKSKEEILAINKPFKMIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYDTQKEMDREASQAALQKMLTLLMLPPTFGDLLREEYIGDNGDPQTLQAQFQEMMADSMFVIPALQVAHFQCSRAPVYFYEFQHQPSWLKNIRPPHMKADHGDELPFVFRSFFGGNYIKFTEEEEQLSRKMMKYWANFARNGNPNGEGLPHWPLFDQEEQYLQLNLQPAVGRALKAHRLQFWKKALPQKIQELEEPEERHTEL", "length": 559 }, "evidence": [ { "id": "MGI:2385905", "url": "https://alliancegenome.org/gene/MGI:2385905#orthology", "database": "AGR" }, { "id": "MGI:1919611", "url": "https://alliancegenome.org/gene/MGI:1919611#orthology", "database": "AGR" }, { "id": "MGI:3648740", "url": "https://alliancegenome.org/gene/MGI:3648740#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O70631-1", "protein_name": "Acylcarnitine hydrolase", "gene_name": "Ces2c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARKQPHSWLNAVLFGLLLILIHVWGQDSPESSSIRTTHTGQVRGKLDHVRDTKAGVHTFLGIPFAKAPVGPLRFAPPEDPEPWSGVRDGTSHPAMCLQNIDMLDEVGLTDMKMILSSIPMSEDCLYLNIYTPAHAHEGSNLPVMVCIHGGALVIGMASMCDGSLLAVNEDLVVVAIQYRLGVLGFFSTGDEHARGNWGYLDQVAALRWVQQNIAHFGGNPNRVTIFGVSAGGTSVSSHVISPMSQGLFHGAIMESGVALLPDLISETSETVSTTVAKLSGCEATDSETLVRCLRAKSGAEILVINKVFKMIPAVVDGEFLPRHPKELLASEDFHPVPSIIGVNTDEYCCTIPMVMGTAQIIKELSRENLQAVLKDTAAQMMLPPECGDLLMEEYMGNTDDPQTLQIQYAEMMGDFLFVIPALQVAHFQRSHAPVYFYEFQHAPSYFKNVRPPHVKADHADEVPFVFGSFFWGIKVDFTEEEKLLSRRMMKYWANFARHGNPNSEGLPYWPVLDHDEQYLQLDTQPAVDRALKARRLQFWTKTLPQKIQELNGAQKNHAEL", "length": 561 }, "evidence": [ { "id": "MGI:2385905", "url": "https://alliancegenome.org/gene/MGI:2385905#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P07140-1", "protein_name": "Acetylcholinesterase", "gene_name": "Ace", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAISCRQSRVLPMSLPLPLTIPLPLVLVLSLHLSGVCGVIDRLVVQTSSGPVRGRSVTVQGREVHVYTGIPYAKPPVEDLRFRKPVPAEPWHGVLDATRLSATCVQERYEYFPGFSGEEIWNPNTNVSEDCLYINVWAPAKARLRHGRGANGGEHPNGKQADTDHLIHNGNPQNTTNGLPILIWIYGGGFMTGSATLDIYNADIMAAVGNVIVASFQYRVGAFGFLHLAPEMPSEFAEEAPGNVGLWDQALAIRWLKDNAHAFGGNPEWMTLFGESAGSSSVNAQLMSPVTRGLVKRGMMQSGTMNAPWSHMTSEKAVEIGKALINDCNCNASMLKTNPAHVMSCMRSVDAKTISVQQWNSYSGILSFPSAPTIDGAFLPADPMTLMKTADLKDYDILMGNVRDEGTYFLLYDFIDYFDKDDATALPRDKYLEIMNNIFGKATQAEREAIIFQYTSWEGNPGYQNQQQIGRAVGDHFFTCPTNEYAQALAERGASVHYYYFTHRTSTSLWGEWMGVLHGDEIEYFFGQPLNNSLQYRPVERELGKRMLSAVIEFAKTGNPAQDGEEWPNFSKEDPVYYIFSTDDKIEKLARGPLAARCSFWNDYLPKVRSWAGTCDGDSGSASISPRLQLLGIAALIYICAALRTKRVF", "length": 649 }, "evidence": [ { "id": "HGNC:108", "url": "https://alliancegenome.org/gene/HGNC:108#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P10959-1", "protein_name": "Carboxylesterase 1C", "gene_name": "Ces1c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWLCALVWASLAVCPIWGHPSSPPVVDTTKGKVLGKYVSLEGFTQPVAVFLGVPFAKPPLGSLRFAPPEPAEPWSFVKNTTTYPPMCSQDGVVGKLLADMLSTGKESIPLEFSEDCLYLNIYSPADLTKNSRLPVMVWIHGGGLIIGGASPYSGLALSAHENVVVVTIQYRLGIWGLFSTGDEHSRGNWAHLDQLAALRWVQDNIANFGGNPDSVTIFGESAGGVSVSALVLSPLAKNLFHRAISESGVVLTTNLDKKNTQAVAQMIATLSGCNNTSSAAMVQCLRQKTEAELLELTVKLDNTSMSTVIDGVVLPKTPEEILTEKSFNTVPYIVGFNKQEFGWIIPTMMGNLLSEGRMNEKMASSFLKRFSPNLNISESVIPAIIEKYLRGTDDPAKKKELLLDMFSDVFFGIPAVLMSRSLRDAGAPTYMYEFQYRPSFVSDQRPQTVQGDHGDEIFSVFGTPFLKEGASEEETNLSKLVMKFWANFARNGNPNGEGLPHWPKYDQKEGYLQIGATTQQAQKLKGEEVAFWTELLAKNPPQTEHTEHT", "length": 549 }, "evidence": [ { "id": "HGNC:1863", "url": "https://alliancegenome.org/gene/HGNC:1863#orthology", "database": "AGR" }, { "id": "MGI:3779470", "url": "https://alliancegenome.org/gene/MGI:3779470#orthology", "database": "AGR" }, { "id": "MGI:95420", "url": "https://alliancegenome.org/gene/MGI:95420#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P18167-1", "protein_name": "Esterase P", "gene_name": "Est-P", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSIFKRLLCLTLLWIAALESEADPLIVEITNGKIRGKDNGLYYSYESIPNAEHPTGALRFEAPQPYSHHWTDVFNATQSPVECMQWNQFINENNKLMGDEDCLTVSIYKPKKPNRSSFPVVVLLHGGAFMFGSGSIYGHDSIMREGTLLVVKISFGLGPLGFASTGDRHLPGNYGLKDQRLALQWIKKNIAHFGGMPDNIVLIGHSAGGASAHLQLLHEDFKHLAKGAISVSGNALDPWVIQQGGRRRAFELGRIVGCGHTNVSAELKDCLKSKPASDIVSAVRSFLVFSYVPFSAFGPVVEPSDAPDAFLTEDPRAVIKSGKFAQVPWAVTYTTEDGGYNAAQLLERNKLTGESWIDLLNDRWFDWAPYLLFYRDAKKTIKDMDDLSFDLRQQYLADRRFSVESYWNVQRMFTDVLFKNSVPSAIDLHRKYGKSPVYSFVYDNPTDSGVGQLLSNRTDVHFGTVHGDDFFLIFNTAAYRTGIRPDEEVISKKFIGMLEDFALNDKGTLTFGECNFQNNVNSKEYQVLRISRNACKNEEYARFP", "length": 544 }, "evidence": [ { "id": "HGNC:108", "url": "https://alliancegenome.org/gene/HGNC:108#orthology", "database": "AGR" }, { "id": "HGNC:1863", "url": "https://alliancegenome.org/gene/HGNC:1863#orthology", "database": "AGR" }, { "id": "MGI:88378", "url": "https://alliancegenome.org/gene/MGI:88378#orthology", "database": "AGR" }, { "id": "MGI:95420", "url": "https://alliancegenome.org/gene/MGI:95420#orthology", "database": "AGR" }, { "id": "RGD:70896", "url": "https://alliancegenome.org/gene/RGD:70896#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P21836-1", "protein_name": "Acetylcholinesterase", "gene_name": "Ache", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRPPWYPLHTPSLAFPLLFLLLSLLGGGARAEGREDPQLLVRVRGGQLRGIRLKAPGGPVSAFLGIPFAEPPVGSRRFMPPEPKRPWSGVLDATTFQNVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPASPTPVLIWIYGGGFYSGAASLDVYDGRFLAQVEGAVLVSMNYRVGTFGFLALPGSREAPGNVGLLDQRLALQWVQENIAAFGGDPMSVTLFGESAGAASVGMHILSLPSRSLFHRAVLQSGTPNGPWATVSAGEARRRATLLARLVGCPPGGAGGNDTELIACLRTRPAQDLVDHEWHVLPQESIFRFSFVPVVDGDFLSDTPEALINTGDFQDLQVLVGVVKDEGSYFLVYGVPGFSKDNESLISRAQFLAGVRIGVPQASDLAAEAVVLHYTDWLHPEDPTHLRDAMSAVVGDHNVVCPVAQLAGRLAAQGARVYAYIFEHRASTLTWPLWMGVPHGYEIEFIFGLPLDPSLNYTTEERIFAQRLMKYWTNFARTGDPNDPRDSKSPQWPPYTTAAQQYVSLNLKPLEVRRGLRAQTCAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKNQFDHYSKQERCSDL", "length": 614 }, "evidence": [ { "id": "HGNC:108", "url": "https://alliancegenome.org/gene/HGNC:108#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P22303-1", "protein_name": "Acetylcholinesterase", "gene_name": "ACHE", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRPPQCLLHTPSLASPLLLLLLWLLGGGVGAEGREDAELLVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPEDPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQYVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKNQFDHYSKQDRCSDL", "length": 614 }, "evidence": [ { "id": "HGNC:108", "url": "https://alliancegenome.org/gene/HGNC:108#orthology", "database": "AGR" }, { "id": "FB:FBgn0027584", "url": "https://alliancegenome.org/gene/FB:FBgn0027584#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P23141-1", "protein_name": "Liver carboxylesterase 1", "gene_name": "CES1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWLRAFILATLSASAAWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKLKDKEVAFWTNLFAKKAVEKPPQTEHIEL", "length": 567 }, "evidence": [ { "id": "HGNC:1863", "url": "https://alliancegenome.org/gene/HGNC:1863#orthology", "database": "AGR" }, { "id": "MGI:2148202", "url": "https://alliancegenome.org/gene/MGI:2148202#orthology", "database": "AGR" }, { "id": "MGI:3779470", "url": "https://alliancegenome.org/gene/MGI:3779470#orthology", "database": "AGR" }, { "id": "MGI:88378", "url": "https://alliancegenome.org/gene/MGI:88378#orthology", "database": "AGR" }, { "id": "MGI:95420", "url": "https://alliancegenome.org/gene/MGI:95420#orthology", "database": "AGR" }, { "id": "RGD:70896", "url": "https://alliancegenome.org/gene/RGD:70896#orthology", "database": "AGR" }, { "id": "MGI:3648919", "url": "https://alliancegenome.org/gene/MGI:3648919#orthology", "database": "AGR" }, { "id": "MGI:95432", "url": "https://alliancegenome.org/gene/MGI:95432#orthology", "database": "AGR" }, { "id": "MGI:1922954", "url": "https://alliancegenome.org/gene/MGI:1922954#orthology", "database": "AGR" }, { "id": "MGI:2142687", "url": "https://alliancegenome.org/gene/MGI:2142687#orthology", "database": "AGR" }, { "id": "FB:FBgn0027584", "url": "https://alliancegenome.org/gene/FB:FBgn0027584#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P23953-1", "protein_name": "Carboxylesterase 1C", "gene_name": "Ces1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWLHALVWASLAVCPILGHSLLPPVVDTTQGKVLGKYISLEGFEQPVAVFLGVPFAKPPLGSLRFAPPQPAEPWSFVKNATSYPPMCSQDAGWAKILSDMFSTEKEILPLKISEDCLYLNIYSPADLTKSSQLPVMVWIHGGGLVIGGASPYNGLALSAHENVVVVTIQYRLGIWGLFSTGDEHSPGNWAHLDQLAALRWVQDNIANFGGNPDSVTIFGESSGGISVSVLVLSPLGKDLFHRAISESGVVINTNVGKKNIQAVNEIIATLSQCNDTSSAAMVQCLRQKTESELLEISGKLVQYNISLSTMIDGVVLPKAPEEILAEKSFNTVPYIVGFNKQEFGWIIPMMLQNLLPEGKMNEETASLLLRRFHSELNISESMIPAVIEQYLRGVDDPAKKSELILDMFGDIFFGIPAVLLSRSLRDAGVSTYMYEFRYRPSFVSDKRPQTVEGDHGDEIFFVFGAPLLKEGASEEETNLSKMVMKFWANFARNGNPNGEGLPHWPEYDEQEGYLQIGATTQQAQRLKAEEVAFWTELLAKNPPETDPTEHTEHK", "length": 554 }, "evidence": [ { "id": "HGNC:1863", "url": "https://alliancegenome.org/gene/HGNC:1863#orthology", "database": "AGR" }, { "id": "MGI:95420", "url": "https://alliancegenome.org/gene/MGI:95420#orthology", "database": "AGR" }, { "id": "FB:FBgn0027584", "url": "https://alliancegenome.org/gene/FB:FBgn0027584#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P37136-1", "protein_name": "Acetylcholinesterase", "gene_name": "Ache", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRPPWYPLHTPSLASPLLFLLLSLLGGGARAEGREDPQLLVRVRGGQLRGIRLKAPGGPVSAFLGIPFAEPPVGSRRFMPPEPKRPWSGILDATTFQNVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLIWIYGGGFYSGASSLDVYDGRFLAQVEGTVLVSMNYRVGTFGFLALPGSREAPGNVGLLDQRLALQWVQENIAAFGGDPMSVTLFGESAGAASVGMHILSLPSRSLFHRAVLQSGTPNGPWATVSAGEARRRATLLARLVGCPPGGAGGNDTELISCLRTRPAQDLVDHEWHVLPQESIFRFSFVPVVDGDFLSDTPDALINTGDFQDLQVLVGVVKDEGSYFLVYGVPGFSKDNESLISRAQFLAGVRIGVPQASDLAAEAVVLHYTDWLHPEDPAHLRDAMSAVVGDHNVVCPVAQLAGRLAAQGARVYAYIFEHRASTLTWPLWMGVPHGYEIEFIFGLPLDPSLNYTVEERIFAQRLMQYWTNFARTGDPNDPRDSKSPRWPPYTTAAQQYVSLNLKPLEVRRGLRAQTCAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKNQFDHYSKQERCSDL", "length": 614 }, "evidence": [ { "id": "HGNC:108", "url": "https://alliancegenome.org/gene/HGNC:108#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5GRG2-1", "protein_name": "Carboxylesterase 5A", "gene_name": "Ces5a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGDWVHTGQALIWVLWIFAAIIRGSVTEEPHRYTRLGWVQGKQATVLGRLEPVNVFLGIPFAAPPLGPLRFSNPQPPIPWHDLREATTYPNVCFQNLEWLFIYQNLLKVHYPKLGVSEDCLYLNIYAPAYANDGSRLPVMMWIPGGGFETGSASIFDGSALAAYEDVLIVTIQYRLGIFGFFNTQNQHAPGNWAFQDQLAALQWVRENINYFGGNPDSVTIFGGSAGAISISSLILSPLSAGLFHRAIMQSGVAIIPSLKNFDDELKHGLQVVADVCKCNVSDSKVLLKCLREKSSLELLSLGQKTKAFTRVVDGSFFPEEPMELLSQKTFKTVPSIIGVNNQECGYILPMREAPEILFGSNESTALTLIHVLLHIPPQYMHIVAKDYFHGKHSLTDIRDTLLDLFGDVFFVVPGLVTARNHRDADGPVYFYEFQHRPNCFQNTRPAFVKADHTDEIRFVFGGPFLEGDVVMFEEATEDEKLLSRKMMSYWANFARSGDPNGDDLPLWPAYDQNESYLKLDVNISTGWRLKDRRVEFWTDTLPLIMSASKALLSPTFPLILFSLLPPSLLSIAS", "length": 575 }, "evidence": [ { "id": "MGI:1915185", "url": "https://alliancegenome.org/gene/MGI:1915185#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5XG92-1", "protein_name": "Carboxylesterase 4A", "gene_name": "CES4A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRWILCWSLTLCLMAQTALGALHTKRPQVVTKYGTLQGKQMHVGKTPIQVFLGVPFSRPPLGILRFAPPEPPEPWKGIRDATTYPPGCLQESWGQLASMYVSTRERYKWLRFSEDCLYLNVYAPARAPGDPQLPVMVWFPGGAFIVGAASSYEGSDLAAREKVVLVFLQHRLGIFGFLSTDDSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGLMMSPLASGLFHRAISQSGTALFRLFITSNPLKVAKKVAHLAGCNHNSTQILVNCLRALSGTKVMRVSNKMRFLQLNFQRDPEEIIWSMSPVVDGVVIPDDPLVLLTQGKVSSVPYLLGVNNLEFNWLLPYIMKFPLNRQAMRKETITKMLWSTRTLLNITKEQVPLVVEEYLDNVNEHDWKMLRNRMMDIVQDATFVYATLQTAHYHRDAGLPVYLYEFEHHARGIIVKPRTDGADHGDEMYFLFGGPFATGLSMGKEKALSLQMMKYWANFARTGNPNDGNLPCWPRYNKDEKYLQLDFTTRVGMKLKEKKMAFWMSLYQSQRPEKQRQF", "length": 561 }, "evidence": [ { "id": "MGI:2384581", "url": "https://alliancegenome.org/gene/MGI:2384581#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q63880-1", "protein_name": "Carboxylesterase 3A", "gene_name": "Ces3a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTNMETTAQAGSSVRVWMACLLLIFPTTVIGPKVTQPEVDTPLGRVRGRQVGVKDTDRMVNVFLGIPFAQAPLGPLRFSAPLPPQPWEGVRDASINPPMCLQDVERMSNSRFTLNEKMKIFPISEDCLTLNIYSPTEITAGDKRPVMVWIHGGSLLVGSSTSHDGSALAAYGDVVVVTVQYRLGIFGFLSTGDKHMPGNRGFLDVVAALRWVQGNIAPFGGDPNCVTIFGNSAGGIIVSSLLLSPMSAGLFHRAISQSGVVISKILEDLNAWSEAQNFANSVACGSASPAELVQCLLQKEGKDLITKKNVNISYTVNDSFFPQRPQKLLANKQFPTVPYLLGVTNHEFGWLLLKFWNILDKMEHLSQEDLLENSRPLLAHMQLPPEIMPTVIDEYLDNGSDESATRYALQELLGDITLVIPTLIFSKYLQDAGCPVFLYEFQHTPSSFAKFKPAWVKADHSSENAFVFGGPFLTDESSLLAFPEATEEEKQLSLTMMAQWSQFARTGNPNGKGLPPWPQLNQLEQYLEIGLEPRTGVKLKKGRLQFWTETLPRKIQEWHREQRSRKVPEEL", "length": 571 }, "evidence": [ { "id": "MGI:102773", "url": "https://alliancegenome.org/gene/MGI:102773#orthology", "database": "AGR" }, { "id": "FB:FBgn0027584", "url": "https://alliancegenome.org/gene/FB:FBgn0027584#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q64176-1", "protein_name": "Carboxylesterase 1E", "gene_name": "Ces1e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCLSALILVSLAAFTAGAGHPSSPPMVDTVQGKVLGKYISLEGFTQPVAVFLGVPFAKPPLGSLRFAPPQPAEPWSSVKNATSYPPMCFQDPVTGQIVNDLLTNRKEKIPLQFSEDCLYLNIYTPADLTKSDRLPVMVWIHGGGLVLGGASTYDGLVLSTHENVVVVVIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALHWVQDNIAKFGGDPGSVTIFGESAGGESVSVLVLSPLAKNLFQRAISESGVALTAGLVKKNTRPLAEKIAVISGCKNTTSAAMVHCLRQKTEEELLGTTLKLNLFKLDLHGDSRQSHPFVPTVLDGVLLPKMPEEILAEKNFNTVPYIVGINKQEFGWILPTMMNYPPSDVKLDQMTAMSLLKKSSFLLNLPEDAIAVAIEKYLRDKDYTGRNKDQLLELIGDVVFGVPSVIVSRGHRDAGAPTYMYEFQYSPSFSSEMKPDTVVGDHGDEIYSVFGAPILRGGTSEEEINLSKMMMKFWANFARNGNPNGQGLPHWPEYDQKEGYLQIGATTQQAQKLKEKEVAFWTELLAKKQLPTEHTEL", "length": 562 }, "evidence": [ { "id": "HGNC:1863", "url": "https://alliancegenome.org/gene/HGNC:1863#orthology", "database": "AGR" }, { "id": "MGI:95432", "url": "https://alliancegenome.org/gene/MGI:95432#orthology", "database": "AGR" }, { "id": "FB:FBgn0027584", "url": "https://alliancegenome.org/gene/FB:FBgn0027584#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q68G49-1", "protein_name": "Carboxylic ester hydrolase", "gene_name": "Ces1dl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLYPLVWLFLAACTAWGYPSSPPVVNTVKGKVLGKYVNLEGFAQPVAVFLGIPFAKSPLGSLRFAPPQPAESWNFVKNTTSYPPIYSLSTSRCSQDAVGGQVLSELFTNRKENIPLQFSEDCLYLNVYTPADLTKNSRLPVMVWIHGGGLVVGGSSTYDGQALSAHENVVVVTIQYRLGIWGFFSTGDEHSQGNWGHLDQLAALHWVQDNIANFGGNPGSVTIFGESAGGFSVSVLVLSPLAKNLFHRAISESGVSLNTALITTDSKPIANLIATLSGCKTTTSAVMVHCLRQKTEDELLETSLKLNLFKLDLFGNPKESYPFLPTVIDGVVLSKTPEEILAEKSFNTVPYIVGINKQEFGWIIPMLMGYPLSEGKLDQKTANSLLWKSYPTLKISEKMIPMASEKYLGGTDDPAERKDLFKDLVADVIFGVPSVMVSRSHRDAGAPTFMYEFEYRPSFVSAMRPKTVIGDHGDEIFSVFGSPFLKDGASEEETNLSKMVMKYWANFARNGNPNGGGLPHWPEYDQKEGYLKIGASTQAAQRLKDKEVAFWSELKAKEAAEEPSHWKHVEL", "length": 572 }, "evidence": [ { "id": "HGNC:1863", "url": "https://alliancegenome.org/gene/HGNC:1863#orthology", "database": "AGR" }, { "id": "MGI:2148202", "url": "https://alliancegenome.org/gene/MGI:2148202#orthology", "database": "AGR" }, { "id": "MGI:88378", "url": "https://alliancegenome.org/gene/MGI:88378#orthology", "database": "AGR" }, { "id": "RGD:70896", "url": "https://alliancegenome.org/gene/RGD:70896#orthology", "database": "AGR" }, { "id": "FB:FBgn0027584", "url": "https://alliancegenome.org/gene/FB:FBgn0027584#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6AW46-1", "protein_name": "Carboxylesterase 5A", "gene_name": "Ces5a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGDWVRPGQALIWVIWIFGAIIEGSVTEEPHRYTKLGWVQGKQATVLGRLEPVNVFLGIPFAAPPLGPLRFSKPQPPIPWDNLREATAYPNLCFQNLEWLFIYQNLLKVSYPILGMSEDCLYLNIYAPCHANNGSSLPVMVWIPGGGFETGSASIFDGSALAVYEDVLVVTIQYRLGIFGFFTTQNQHAPGNWAFWDQLAALLWVRENIKYFGGNPDSVTIFGNSAGAISISSLILSPLSADLFHRAIMQSGVAIIPSLKSSDNDLKHDLQVVANVCDCNVSDSKALLKCLREKSSLELMSLSQKAKSFTRVVDGSFFSEEPLELLSQKTLKIVPSIIGVNNQECGYILPVRDTPEILLGSNESTALTLIHTLLHIPTQHLYIVTKEYFHGKHSPTDIRDTLLDLFGDVFFVVPGLVTARYHRDSGGPVYFYEFQHRPHCFQNSRPAFVKADHTDEIRFVFGGPFLKGDVVMFEEATEEEKLLSRKMMKYWANFARSGDPNGADLPPWPVYDENEQYLELDVNISTGRRLKDQRVEFWTDTLPLILSASKALLSPTFSLILLSLLSPVLLSAAS", "length": 575 }, "evidence": [ { "id": "MGI:1915185", "url": "https://alliancegenome.org/gene/MGI:1915185#orthology", "database": "AGR" }, { "id": "FB:FBgn0027584", "url": "https://alliancegenome.org/gene/FB:FBgn0027584#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6NT32-1", "protein_name": "Carboxylesterase 5A", "gene_name": "CES5A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSGNWVHPGQILIWAIWVLAAPTKGPSAEGPQRNTRLGWIQGKQVTVLGSPVPVNVFLGVPFAAPPLGSLRFTNPQPASPWDNLREATSYPNLCLQNSEWLLLDQHMLKVHYPKFGVSEDCLYLNIYAPAHADTGSKLPVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILSPMAKGLFHKAIMESGVAIIPYLEAHDYEKSEDLQVVAHFCGNNASDSEALLRCLRTKPSKELLTLSQKTKSFTRVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNHECGFLLPMKEAPEILSGSNKSLALHLIQNILHIPPQYLHLVANEYFHDKHSLTEIRDSLLDLLGDVFFVVPALITARYHRDAGAPVYFYEFRHRPQCFEDTKPAFVKADHADEVRFVFGGAFLKGDIVMFEGATEEEKLLSRKMMKYWATFARTGNPNGNDLSLWPAYNLTEQYLQLDLNMSLGQRLKEPRVDFWTSTIPLILSASDMLHSPLSSLTFLSLLQPFFFFCAP", "length": 575 }, "evidence": [ { "id": "MGI:1915185", "url": "https://alliancegenome.org/gene/MGI:1915185#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6UWW8-1", "protein_name": "Carboxylesterase 3", "gene_name": "CES3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MERAVRVESGVLVGVVCLLLACPATATGPEVAQPEVDTTLGRVRGRQVGVKGTDRLVNVFLGIPFAQPPLGPDRFSAPHPAQPWEGVRDASTAPPMCLQDVESMNSSRFVLNGKQQIFSVSEDCLVLNVYSPAEVPAGSGRPVMVWVHGGALITGAATSYDGSALAAYGDVVVVTVQYRLGVLGFFSTGDEHAPGNQGFLDVVAALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGLVLSPVAAGLFHRAITQSGVITTPGIIDSHPWPLAQKIANTLACSSSSPAEMVQCLQQKEGEELVLSKKLKNTIYPLTVDGTVFPKSPKELLKEKPFHSVPFLMGVNNHEFSWLIPRGWGLLDTMEQMSREDMLAISTPVLTSLDVPPEMMPTVIDEYLGSNSDAQAKCQAFQEFMGDVFINVPTVSFSRYLRDSGSPVFFYEFQHRPSSFAKIKPAWVKADHGAEGAFVFGGPFLMDESSRLAFPEATEEEKQLSLTMMAQWTHFARTGDPNSKALPPWPQFNQAEQYLEINPVPRAGQKFREAWMQFWSETLPSKIQQWHQKQKNRKAQEDL", "length": 571 }, "evidence": [ { "id": "MGI:102773", "url": "https://alliancegenome.org/gene/MGI:102773#orthology", "database": "AGR" }, { "id": "MGI:3644960", "url": "https://alliancegenome.org/gene/MGI:3644960#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R0W5-1", "protein_name": "Carboxylesterase 4A", "gene_name": "Ces4a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEAGWNMKWILGLSLTLCLVVQTALGALHTKEPLLITKHGILQGKQVHVGDTPIQVFLGIPFSKPPVGTRRFAPPEPPLPWNGIRDATTYPPSCLQESWGQILSMYLNTRKQYKWLHFSEDCLYLNVYAPVLAPGAPLLPVMVWFPGGAFLAGSASTYEGSELAARGKVVLVFLQYRLGILGFFSTGNSHARGNWGLLDQIAALRWVQENIEAFGGDPDSVTLFGQSAGAMSVSGLMVSPLAQGLFHQAISQSGTAVLKAFITPDPLTSAKKIAHLAGCDHNSTKVMVECLRSLSAEEVTLVSKRMSFFQANSHKDPKEIVWFLSPVVDGVVFPEDPVVLLTRGQVKPVPYLLGVNNAEFEWNLPFLMKIQLNQRMMNQTNINKILWSFNVLLNITKEQVPVVAREYLNDAISNHDWKMFRNRLIDLIGDATFVYATLQAARYHRDAGSPVYLYEFKHHASSGIIIKPYNGADHGDELSYLFGSPFSKGSSAGEEKEFSLQMMKYWANFAHTGNPNGEKLPYWPRFDKDEKYLQLDFDTRVGVKLKEKKMAFWSQLRQSQKP", "length": 563 }, "evidence": [ { "id": "MGI:2384581", "url": "https://alliancegenome.org/gene/MGI:2384581#orthology", "database": "AGR" }, { "id": "FB:FBgn0027584", "url": "https://alliancegenome.org/gene/FB:FBgn0027584#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VCC2-1", "protein_name": "Liver carboxylesterase 1", "gene_name": "Ces1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWLCALSLISLTACLSLGHPSLPPVVHTVHGKVLGKYVTLEGFSQPVAVFLGVPFAKPPLGSLRFAPPEPAEPWSFVKHTTSYPPLCYQNPEAALRLAELFTNQRKIIPHKFSEDCLYLNIYTPADLTQNSRLPVMVWIHGGGLVIDGASTYDGVPLAVHENVVVVVIQYRLGIWGFFSTEDEHSRGNWGHLDQVAALHWVQDNIANFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAIAQSSVIFNPCLFGRAARPLAKKIAALAGCKTTTSAAMVHCLRQKTEDELLEVSLKMKFGTVDFLGDPRESYPFLPTVIDGVLLPKAPEEILAEKSFNTVPYMVGINKHEFGWIIPMFLDFPLSERKLDQKTAASILWQAYPILNISEKLIPAAIEKYLGGTEDPATMTDLFLDLIGDIMFGVPSVIVSRSHRDAGAPTYMYEYQYRPSFVSDDRPQELLGDHADELFSVWGAPFLKEGASEEEINLSKMVMKFWANFARNGNPNGEGLPHWPEYDQKEGYLQIGVPAQAAHRLKDKEVDFWTELRAKETAERSSHREHVEL", "length": 565 }, "evidence": [ { "id": "HGNC:1863", "url": "https://alliancegenome.org/gene/HGNC:1863#orthology", "database": "AGR" }, { "id": "MGI:88378", "url": "https://alliancegenome.org/gene/MGI:88378#orthology", "database": "AGR" }, { "id": "RGD:70896", "url": "https://alliancegenome.org/gene/RGD:70896#orthology", "database": "AGR" }, { "id": "FB:FBgn0027584", "url": "https://alliancegenome.org/gene/FB:FBgn0027584#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VCT4-1", "protein_name": "Carboxylesterase 1D", "gene_name": "Ces1d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLYPLIWLSLAACTAWGYPSSPPVVNTVKGKVLGKYVNLEGFTQPVAVFLGVPFAKPPLGSLRFAPPQPAEPWSFVKNTTSYPPMCSQDAVGGQVLSELFTNRKENIPLQFSEDCLYLNIYTPADLTKNSRLPVMVWIHGGGLVVGGASTYDGLALSAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIANFGGNPGSVTIFGESAGGFSVSVLVLSPLAKNLFHRAISESGVSLTAALITTDVKPIAGLVATLSGCKTTTSAVMVHCLRQKTEDELLETSLKLNLFKLDLLGNPKESYPFLPTVIDGVVLPKAPEEILAEKSFSTVPYIVGINKQEFGWIIPTLMGYPLAEGKLDQKTANSLLWKSYPTLKISENMIPVVAEKYLGGTDDLTKKKDLFQDLMADVVFGVPSVIVSRSHRDAGASTYMYEFEYRPSFVSAMRPKAVIGDHGDEIFSVFGSPFLKDGASEEETNLSKMVMKFWANFARNGNPNGGGLPHWPEYDQKEGYLKIGASTQAAQRLKDKEVSFWAELRAKESAQRPSHREHVEL", "length": 565 }, "evidence": [ { "id": "HGNC:1863", "url": "https://alliancegenome.org/gene/HGNC:1863#orthology", "database": "AGR" }, { "id": "MGI:2148202", "url": "https://alliancegenome.org/gene/MGI:2148202#orthology", "database": "AGR" }, { "id": "RGD:70896", "url": "https://alliancegenome.org/gene/RGD:70896#orthology", "database": "AGR" }, { "id": "FB:FBgn0027584", "url": "https://alliancegenome.org/gene/FB:FBgn0027584#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VCU1-1", "protein_name": "Carboxylesterase 3B", "gene_name": "Ces3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTNMRTMIPAGSSVLVWVTCLLLAFVTTVTGPKVIQPEVDTPLGRVRGRQVGVKDTDRMVNVFLGIPFAQAPVGPLRFSAPLPPQPWEGVRDASINPPMCLQDVEKMINSRFGLNEKIKIFPISEDCLTLNIYSPTEITAGDKRPVMVWIHGGSLLVGSSTSQDGSALAAYGDVVVVTVQYRLGIFGFLSTGDKHMPGNRGFLDVVAALRWVQGNIAPFGGDPNCVTIFGNSAGGMIVSSLFLSPISAGLFHRAISQSGIVTTIMMEDMKPWPEAQNFANSVACGSASPAELVQCLLQKEGKDLIKQKNVNISYIVNDSFFPQRPEKLLADQQFPTVPYLLGVTNHEFGWLLLKSLNILDKLEHLSREDLLEISRPFLAIMEVPPEIMPTVIDEYLDNGSDQSATRYAFQELLGDISFIIPTLNFSKYLRDAGCPVFLYEFQHTPSSFAKFKPAWVKADHASENSFVFGGPFLTDESSLLAFPEATEEEKQLSLTMMAQWSQFARTGNPNGKGLPPWPQLNQLEQYLEIGLESRTGVKLKKGRLQFWTETLPRKIQEWHREQRSRKVPEEL", "length": 571 }, "evidence": [ { "id": "MGI:3644960", "url": "https://alliancegenome.org/gene/MGI:3644960#orthology", "database": "AGR" }, { "id": "FB:FBgn0027584", "url": "https://alliancegenome.org/gene/FB:FBgn0027584#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q91WG0-1", "protein_name": "Acylcarnitine hydrolase", "gene_name": "Ces2c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTRNQLHNWLNAGFFGLLLLLIHVQGQDSPEANPIRNTHTGQIQGSLIHVKDTKAGVHTFLGIPFAKPPVGPLRFAPPEAPEPWSGVRDGTAHPAMCLQNLDMLNEAGLPDMKMMLSSFPMSEDCLYLNIYTPAHAHEGSNLPVMVWIHGGALVIGMASMFDGSLLTVNEDLVVVTIQYRLGVLGFFSTGDQHARGNWGYLDQAAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSHVVSPMSQGLFHGAIMESGVALLPDLISETSEMVSTTVAKLSGCEAMDSQALVRCLRGKSEAEILAINKVFKMIPAVVDGEFFPRHPKELLASEDFHPVPSIIGVNNDEFGWSIPVVMGSAQMIKGITRENLQAVLKDTAVQMMLPPECSDLLMEEYMGDTEDAQTLQIQFTEMMGDFMFVIPALQVAHFQRSHAPVYFYEFQHPPSYFKDVRPPHVKADHADEIPFVFASFFWGMKLDFTEEEELLSRRMMKYWANFARHGNPNSEGLPYWPVMDHDEQYLQLDIQPAVGRALKAGRLQFWTKTLPQKIQELKASQDKHREL", "length": 561 }, "evidence": [ { "id": "MGI:2385905", "url": "https://alliancegenome.org/gene/MGI:2385905#orthology", "database": "AGR" }, { "id": "FB:FBgn0027584", "url": "https://alliancegenome.org/gene/FB:FBgn0027584#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q91WU0-1", "protein_name": "Carboxylesterase 1F", "gene_name": "Ces1f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFLSTLFLVSLATCVICGNPSSPPVVDTAHGKVLGKHVNVEGFSQPVAVFLGIPFAKPPLGSLRFAPPQPAEPWSSVKNATTYPPMCSQDAARGQAVNDLITNRKEKIHLEFSEDCLYLNIYTPADFSKNSRLPVMVWIHGGGLKLGGASSFDGRALSAYENVVVVAIQYRLSIWGFFSTGDEHSRGNWGHLDQVAALHWVQDNIANFGGDPGSVTIFGESAGGYSVSILILSPLSKNLFHRAISESGVAFIPGMFTKDVRPITEQIAVTAGCKTTTSAVIVHCMRQKTEEELLEIMHKLNLYKLSLQGDTKNSDQFVTSVLDGVVLPKDPKEILAEKNFNTVPYIVGINKQECGWLLPTMTGFLPADVKLDKKKAIALLEQFASMTGIPEDIIPVAVEKYTKGSDDPDQIREGVLDAMGDVAFGVPSVIVSRGHRDTGAPTYMYEYQYYPSFSSPQRPKNVVGDHADDVYSVFGAPILREGASEEEINLSKMVMKFWANFARNGNPNGKGLPHWPKYDQKEGYLHIGGTTQQAQRLKEEEVTFWTQSLAKKQPQPYHNEL", "length": 561 }, "evidence": [ { "id": "HGNC:1863", "url": "https://alliancegenome.org/gene/HGNC:1863#orthology", "database": "AGR" }, { "id": "MGI:2142687", "url": "https://alliancegenome.org/gene/MGI:2142687#orthology", "database": "AGR" }, { "id": "FB:FBgn0027584", "url": "https://alliancegenome.org/gene/FB:FBgn0027584#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9DDE3-1", "protein_name": "Acetylcholinesterase", "gene_name": "ache", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKTSDILLLPTVLLTFLFHNCFAQAEPDLVVATRLGRVQGTRLPVPDRSHVIAFLGIPYAEPPIGKRRFKRAEPKKPWNNVFEAKEFSNACYQFVDTSYPGFPGIEMWNPNRVMSEDCLYLNVWVPPTPRPQNLTVMVWIYGGGFYSGSSSLDVYDGRYLAYTEKVVVVSMNYRVGAFGFLALNGSSDAPGNVGLYDQRLALQWVQENIHFFGGNPKQVTIFGESAGAASVGMHVLSPDSRPLFTRAILQSGVPNTPWATVTFDEARRRTTKLGKLVGCTWGNDTELIDCLRNKHPQELIDQEWQVLPWSSLFRFSFVPVVDGVFFPDTPDAMISSGNFKYTQILLGVNQDEGSYFLLYGAPGFSKDNESLISREDFLESVKMGVPHANDIGLEAVILQYTDWMDENNGQKNRDAMDDIVGDQNVICPLQHFAKSYAQYAALHAQSSAAAPGTLGWGNSGPTGYNSGNSHGAVYLYLFDHRASNLAWPEWMGVIHGYEIEFVFGLPLEKRLNYTAEEEKLSRRIMRYWANFARTGNPNVNTDGTMDSRRRWPQFSANEQKHVGLNTEPMKVHKGLRTQFCALWNRFLPRLLNITDNIDDVERQWKVEFHRWSSYMMHWKSQFDHYSKQERCTDL", "length": 634 }, "evidence": [ { "id": "HGNC:108", "url": "https://alliancegenome.org/gene/HGNC:108#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9UKY3-1", "protein_name": "Putative inactive carboxylesterase 4", "gene_name": "CES1P1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWLPALVLATLAASAAWAGHLSSPPLVDTLHGKVLGKFVSLEGFAQPVAVFLGIPFAKPPLGPLRFTLPQPAEPWNFVKNATSYPPMFTQDPKAGQLISELFTNRKENIPLKLSEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSPGNWGHLDQLAALHWVQDNIASFGGNPGSVTIFGGSVGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEVGLRLVRLRLDTPTSLALCS", "length": 287 }, "evidence": [ { "id": "MGI:2148202", "url": "https://alliancegenome.org/gene/MGI:2148202#orthology", "database": "AGR" }, { "id": "MGI:3779470", "url": "https://alliancegenome.org/gene/MGI:3779470#orthology", "database": "AGR" }, { "id": "MGI:88378", "url": "https://alliancegenome.org/gene/MGI:88378#orthology", "database": "AGR" }, { "id": "MGI:95420", "url": "https://alliancegenome.org/gene/MGI:95420#orthology", "database": "AGR" }, { "id": "MGI:1922954", "url": "https://alliancegenome.org/gene/MGI:1922954#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VIB1-1", "protein_name": "Carboxylic ester hydrolase", "gene_name": "alpha-Est9", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSSMAAFDQFKIGLKMVDFKVQQRRYRTSEKTVVSTTYGPIKGVKRKSIYGQSYFSFERIPFAKPPVGELRYKAPQPPEVWTEVRSCTSQGPKPLQKHFVFEMTDGSEDCLYLNVYTKNLYPTKPMPVMVWIYGGGFQFGEASRECYSPDYLLREDVVVISINYRLGPLGTNDDTWKKKHIFNISLPGFLCLDDPELDVPGNAGLKDQVLALRWVKANCSRFGGDSANITIFGDSAGSASVHYMMITEQTHGLFHKAICMSGNTLSPWAVTPQRNWPYRLAVQAGYAGENNTRDVWEFLKNAKGSEIIKANGELCIDEEKKERIGFSFGPVIEPYVTSHCVVPKKPIEMMRTAWSNNIPLIIGGVSNEGLLLYSETKTNPKCLNELDDCRFVVPIELNMDRESALCREYGDQLRQCYYGDKTPSLDTLHEYLQMVSHEYFWFPIYRTVLSRLQYARSAPTYLYRFDFDSKHFNHLRILSCGKKVRGTCHGDDLSYLFYNSLARKLKNHTREYKCIERLVGLWTHFAACGNPNFDPEQEDLWQPVDPAAVEKHQLKCLNISDELKVIDVPDLKKLMVWESFFRRDELL", "length": 587 }, "evidence": [ { "id": "MGI:1919611", "url": "https://alliancegenome.org/gene/MGI:1919611#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VIB3-1", "protein_name": "Carboxylic ester hydrolase", "gene_name": "alpha-Est8", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSFDIAVADQMRIALNYVKFKTNQQRLRSNDKVIADTVYGKVKGVKWQSIYGNNYYSFEGIPFAKPPVGELRFKAPVEPEHWSDVKRCTHVRAKPCQVNIVLKQVQGSEDCLYLNVYTRELHPHRPLPVLVWIYGGGFQMGEASRDLYSPDYIMMEHVVLVVISYRLGALGFLSLADEELDVPGNAGLKDQVMALRWVKRNCQFFGGDPDNITVFGESAGGASTHYMMLTDQAKGLFHKTIIMSGSALAPWAQTPTHINWPYRLAQATGYTGDANDRDIFAHLKKCKASSMLKVAEDIITMEERHQRLTMFSFGPTIEPYLTPHCVIPKSPLEMMRDCWGNSIPMVIGGNSFEGLLMFPEVNKWPELLCQLGDCENLAPQDAHVDEQQRKAFGKKVRELYFGDRTPGRKTILEYSDLFSYKYFWHGIHRTLLSRAHHAPLAPTFLYRFDFDSKHFNIMRIITCGRKVRGTCHADDLSYLFYNAAAKKLKRRTAEFKTIKRLVSMVVHFAISGDPNIPMVCQDEKEQPRGAWLPISKDDKVFQCLNISHDVHVIDLPEAEKLRLWDCIYDRELLY", "length": 574 }, "evidence": [ { "id": "MGI:2385905", "url": "https://alliancegenome.org/gene/MGI:2385905#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VIB5-1", "protein_name": "Carboxylic ester hydrolase", "gene_name": "alpha-Est7", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNKNLGFVERLRWRLKTIEHKVQQYRQSTNETVVADTEYGQVRGIKRLSLYDVPYFSFEGIPYAQPPVGELRFKAPQRPIPWERVRDCSQPKDKAVQVQFVFDKVEGSEDCLYLNVYTNNVKPDKARPVMVWIHGGGFIIGEANREWYGPDYFMKEDVVLVTIQYRLGALGFMSLKSPELNVPGNAGLKDQVLALKWIKNNCASFGGDPNCITVFGESAGGASTHYMMLTDQTQGLFHRGILQSGSAICPWAYNGDITHNPYRIAKLVGYKGEDNDKDVLEFLQNVKAKDLIRVEENVLTLEERMNKIMFAFGPSLEPFSTPECVISKPPKEMMKTAWSNSIPMFIGNTSYEGLLWVPEVKLMPQVLQQLDAGTPFIPKELLATEPSKEKLDSWSAQIRDVHRTGSESTPDNYMDLCSIYYFVFPALRVVHSRHAYAAGAPVYFYRYDFDSEELIFPYRIMRLGRGVKGVSHADDLSYQFSSLLARRLPKESREYRNIERTVGIWTQFAATGNPYSEKINGMDTLTIDPVRKSDEVIKCLNISDDLKFIDLPEWPKLKVWESLYDDNKDLLF", "length": 572 }, "evidence": [ { "id": "MGI:2385905", "url": "https://alliancegenome.org/gene/MGI:2385905#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VIB6-1", "protein_name": "carboxylesterase", "gene_name": "alpha-Est6", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MWKLCQPRSRSRIKCFRFLILRCCPGFKRFSCQSAGDADSKVVKLSVGSVKGRRLSGIYGDEFYSFEGIPFAKPPLGKARFVASQLADPWNSELDARQERPIPLQMDRRSGKVVGSEDCLYLNVYTKHFNESEPPLPVMVYIYGGAFRTGGAVKSKYGPDYLMSRDVVYVLFNYRLCSLGFLSMPSGKLDVPGNAGLHDQLLALQWVSQHIRNFNGDPQNITLFGESAGAASVHFMMCLPQAKGLFHKAIMMSGSMLSPWVNAPDSDGIFCRLATSAGYEGPAEEVPILEFLRNVNAEKLIGHDFISPRDRCFGFLNPFAPVVGGLVAAPFQQLMKEAWSCEVPLLLGGTSFEGLVYYPFCQLDNGYMLELLKHEPAMVLPHELYQSMSVEERNTAADVLVKYHYGPRGITKSNITQILDLFSYKLFWHGIHRVVLSRLSHAQAPTYLYRFDFDSPKLNLMRNQLCGDDIKRGVCHADDLGYIFHKQAQAKQPLDSPEFLTIQRMVGILTTFARTGDPNCPETGPDPWMPVSTKSPFKALNIGQQVECVTQVEKDGLKVWNRLYSDLK", "length": 568 }, "evidence": [ { "id": "MGI:1919611", "url": "https://alliancegenome.org/gene/MGI:1919611#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VIC0-1", "protein_name": "carboxylesterase", "gene_name": "alpha-Est4", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSDDYNEDAPVVQTTHGKVRGILLKSLYDEQFYAFDGIPYAVPPLGTLRFKEPHDLKPWHGIRDCSKPLSKCLQVSTLTKEVEGSEDCLYLNISVKTLNGDPMPVMVYIHGGAFKGGDSSRRAWGPDYFMKENVVYISIGHRLGPLGFLSLNDPDLEVPGNAGLKDVILALRWIRANAANFNGDPERITIFGHSSGSMTVQLLLASPQSEGLFHRAILLAGFSMELNRLPQMEYRLAKHLGYEGDNVDSQVLEFLLKADPALIVSADFFTPLEKRQGHNMPFKPSIESYSTPNAVLLAEPIDLQRTTWSNRIPIILGANSGEGMSIFSFVKMNPSWLKEFQCNPERVLPWTLRNRCDPGQRRQLGQALIHHFCEAHGHELTVDHTNGLVELFTHGFVHAMDRLIQSRLTYGQAPTYLYRFDFDSPDFNFYRIRFMGKEQRGVGHVDELGYIFKLPATFKLDKSRPEFTAIRRLVAMFVQFAATSDPNAPLTKSLVDWKPVTRFGKRMVLNISEELKFIPQPEMPKLKFFDRLYEMAGVPLF", "length": 541 }, "evidence": [ { "id": "HGNC:1863", "url": "https://alliancegenome.org/gene/HGNC:1863#orthology", "database": "AGR" }, { "id": "MGI:2148202", "url": "https://alliancegenome.org/gene/MGI:2148202#orthology", "database": "AGR" }, { "id": "MGI:3779470", "url": "https://alliancegenome.org/gene/MGI:3779470#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VLA3-1", "protein_name": "Carboxylesterase type B domain-containing protein", "gene_name": "Dmel\\CG4382", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MWRLCGFVLLLCGLASGQNSDEDLSKAIPDEEDPIGSNKELSDLVITTALGKIRGTILPSQSGRNFYAFRGIPYAKPPVDRLRFQPPEPVEQWFDTLDATFDGPKCPQLGLVSGDVSEDCLRVNIYTKELPSESQPNVRRPVIVFIHPGGFYSLSGQSKNFAGPQYFMNRRLVLVTFNYRLGSLGFLATGTREAPGNMGLKDQVQLLRWVKLHISRFGGDPSSITLLGYGAGAMAVTLHMVSPMSRGLFHKAIVMSGAVTGQWSLPDHQMDVATKQATLLHCHTENVTEMMDCLKGKHYLEFANTLPKMFEFDRNNPLILWKPVIEPDFGQERFLVEEPIRSYQNDDFMKVPIITGMTKDEFVGPALSILQSPTLLSALNENFESLAPVFFMYNTSDARACNISQELRNHYFPDKLIDANRSLEALSNLYSDALTGFGIHRFVHLAARSTKVYYYRFSYQGARSHIYYPEDAPYGVVHHDDLMYLFVEPSISRMFTEDDDEFRMVDIMVRMFSAFAYKGDPNKPTDLALRDIRWRPFSFKKRYYLDIGKHITLEENLNAENYEIWKRLFPLNWRRQTKEV", "length": 580 }, "evidence": [ { "id": "MGI:2148202", "url": "https://alliancegenome.org/gene/MGI:2148202#orthology", "database": "AGR" }, { "id": "MGI:3779470", "url": "https://alliancegenome.org/gene/MGI:3779470#orthology", "database": "AGR" }, { "id": "MGI:88378", "url": "https://alliancegenome.org/gene/MGI:88378#orthology", "database": "AGR" }, { "id": "MGI:95420", "url": "https://alliancegenome.org/gene/MGI:95420#orthology", "database": "AGR" }, { "id": "MGI:2385905", "url": "https://alliancegenome.org/gene/MGI:2385905#orthology", "database": "AGR" }, { "id": "MGI:2384581", "url": "https://alliancegenome.org/gene/MGI:2384581#orthology", "database": "AGR" }, { "id": "MGI:1915185", "url": "https://alliancegenome.org/gene/MGI:1915185#orthology", "database": "AGR" }, { "id": "MGI:3648919", "url": "https://alliancegenome.org/gene/MGI:3648919#orthology", "database": "AGR" }, { "id": "MGI:1919611", "url": "https://alliancegenome.org/gene/MGI:1919611#orthology", "database": "AGR" }, { "id": "MGI:95432", "url": "https://alliancegenome.org/gene/MGI:95432#orthology", "database": "AGR" }, { "id": "MGI:3648740", "url": "https://alliancegenome.org/gene/MGI:3648740#orthology", "database": "AGR" }, { "id": "MGI:102773", "url": "https://alliancegenome.org/gene/MGI:102773#orthology", "database": "AGR" }, { "id": "MGI:3644960", "url": "https://alliancegenome.org/gene/MGI:3644960#orthology", "database": "AGR" }, { "id": "MGI:1922954", "url": "https://alliancegenome.org/gene/MGI:1922954#orthology", "database": "AGR" }, { "id": "MGI:2142687", "url": "https://alliancegenome.org/gene/MGI:2142687#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VLA4-1", "protein_name": "Carboxylic ester hydrolase", "gene_name": "Dmel\\CG3841", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPRFFQLTWALLLILIGFTTAVTFIGDDPVVELSLGRIQGDTMQSFGNKTIYAFRGIRYAQSPVGQLRFANPVPETSWGDEVFNATSDSLVCPQPGVVSLMSEDCLKINVFTKSFEDKFPVMVYIHGGANVLGSGHSSYEAGPQYLLDQDVVFVAFNYRLGALGFLSTNSSETKGNFGFLDQVMALEWVRDHISHFGGDPELVTIIGISAGSMAVSLHLASPLSAGLFHRAILMSGSATNHFDIDNLFWTRKLARELGCPMYDPTDVVECLRNETWTRIVEVCKAWETYQLVNMKWNYEIDGHFLHNHPTELIKEGNFNKVPLLISFTANEFDYNANVHLENQHLLHDFASNFVDYAPELFLYRHDAQIGEKLKDFYLGDNTTEINSENIENFGQIFSDAYIGHGVHRLVQLASHFTPVYYTRMDYVGDQSLSAPLNGENKPVGVGHADDLHYVLPGYWYGPLMAANDSDVFMMERLTSWFTHFAKTGTPLNSTDIWPPCNSTVLKMLYNGVVTQVGSPGYSNRYAVWDKLFPTAAQGGGAALKLSFAVAIATGVASRLIGKLM", "length": 564 }, "evidence": [ { "id": "MGI:102773", "url": "https://alliancegenome.org/gene/MGI:102773#orthology", "database": "AGR" }, { "id": "MGI:3644960", "url": "https://alliancegenome.org/gene/MGI:3644960#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VLJ1-1", "protein_name": "Carboxylesterase type B domain-containing protein", "gene_name": "Dmel\\CG9289", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MARFSGVVLLLAIVLLAVFVAQGLAEKNANRQKQQKPRPGNQNFGIQKNKRPKPQKVQKQKPNKQQGQNGQEPKVFTTTVPDLGRLRGRTLTTDWTGQKIMQFLDIPYGKAERFRPAEPAPSWKGVLPAHRPHAGCPSIQDLIVFAKLEEDGFDVEDCLRLSVNTKAMEGKSLPVMVYIHGDFFYDGDSVEAAPGYLLEHDVVLVSVRYRLGPFGFLSTLTDEMPGNAAVTDIILALKWVQQHIASFGGDPQRVTLFGQVGGAALVNVLTLSPAVPAGLFHRVIYQSGTALSPAFITDAPLGATKAIGRIAGCKQSTKVDQLNKCLNRLNATMLLAAFSVHGENQPSLSGGAYGGVQLVIGGPSGILPEHPGRLLAAEKFQAYPTMGGSVKHGGTFMLRDIFADIFNETILDDTMTGRQYIDTIIEQANGADPSGSWKEFSDEEIFTQNDVKNGTFKRLTPGLIDLCSTISLKNPVLLVLQANAKKLPNSTYLYSFDYEGEQNRYATGEDEANFVPFDMGVSLTDDNLYLFPWPRFLALNSNRDLKVARRMVALWTSFATTGVPQAPGLPAWPAMNDETGPYMKIDRTVSFGDNYLDEYRIAVEEAKHGYNLVNDEYYDLQEALLAASKLDSLNDANEEDEEDQDDAEGQRAASQTGGQNWVFIARKSTRVQKQ", "length": 674 }, "evidence": [ { "id": "MGI:2148202", "url": "https://alliancegenome.org/gene/MGI:2148202#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VP25-1", "protein_name": "Carboxylic ester hydrolase", "gene_name": "Est-Q", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRRRGVYVMLTLCGVLTAGLTAFLVIFLTGGQGADASETATVTVELYNGQGTVLGNYAYTAWTDRAFMQFRGIPFAEPPIEELRFRPPVARSPWTGTLNALNFGQRCPVITNLDSQMSDAELEDCLTLSVYTKNLSASQPVMFYIYGGGFYNGSSEDHPPNYLLEKDVVLVVPQYRVGALGWLSTYTEELPGNAPIADILMALDWVQMHISSFGGDPQKVTIFGQSAGAGVASSLLLSPKTGDNMFKRAIVQSGSIFASWAINKDPKAQSRRICIQLGCSGCEQHDQLVKCIQKAKVIDILKATASESFSPIVGDLHGILPQQPSELVKSYRRQIPILTGFTQHDGSFVLASYYDALAAKVANVSSLSVRQFSQGINDLVNDTSGLTDNILNRLLFKPQALNSHDHSAAVSSYFDLTTNIFMKSPVITLATKMYTQQRSTPVYVYSFEYEGTYTRFGYEFGNSHYPFNGGVHHSNDNIYLFATHPLEGQDTQMSQKMVDVWTSFAIEGVPRNLSPLSSASGPYNKLNLEVTKGDDLLDTLTAAIDDPDNGRLQREDMEF", "length": 559 }, "evidence": [ { "id": "MGI:95420", "url": "https://alliancegenome.org/gene/MGI:95420#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W243-1", "protein_name": "carboxylesterase", "gene_name": "gas", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDLRVSFSDKLKLGAKIIGHKVVQYKLGTGQTKELATKYGQLKGQQRRTLYDGEPYYSFEGIPFAQPPVGELRFRAPQPPSSWQGVRDCTYAREKPMQRNSITNAAEGSEDCLYLNVYAKRLESPKPLPVMVWIFGGGFQVGGASRELYGPDYFMKHDILLVTINYRVGVLGFLSLKDKELKIPGNAGLKDQIQALRWVKENIASFNGDPESITVFGESAGGASTHILMQTEQARGLFHRAIVQSGSALCAWATQPDRKWPQRLGKELGYAGNLESEKELLEFFQQIPASKLAQYCNSIVTQEEQRDYEILAFAPVIEPYVGDDCVIPKSQQEQLSSAWGNSIPMIIGGTSFEGLFSYRTTLDDPLYMLSAFEAIIPKQVRDAIDKEELAEMVRRLKKSYFDDPDRASMELYECLHILSIKNFWHDIHRTLLARLAYATNLPTYLYRFDMDSPHFNHYRILKCGKKVRGVCHADDISYMFYGILSSKLDKNSPEYRTIERLVGMWTSFATTGDPNCEIIAPVKWDPLRPGGVENCLNIADGLEFIPLPESKQFVVWDSFYTRESLY", "length": 566 }, "evidence": [ { "id": "MGI:102773", "url": "https://alliancegenome.org/gene/MGI:102773#orthology", "database": "AGR" }, { "id": "MGI:3644960", "url": "https://alliancegenome.org/gene/MGI:3644960#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W2F4-1", "protein_name": "carboxylesterase", "gene_name": "clt", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLLRPCGRLIFTRFCSSMKVKVPVKQGVLVGRQKKLVNGLEYNSFLGVPYAEPPVGELRFRSPRPLERFQKQELDCSKEGNVSYQRDPFTLEVAGSEDCLFLNVYAPKVKSTRTPLPVMVWIHGGGFFFGNGNSDFHFPAKLMEQEVIVVTLNYRLGALGFLSLPEEGIHGNMGLKDQRLALEWVQENIASFNGDPNNVTLFGESAGGSSVHLHTFARHAKRLFHKAIMQSGTANMEWVFQNEAPAKTRRLAELLGGGDFGGDSKALLTFLQSEKATPTAILANTLKVLSPDERRRHLPFAFKPVVEDSSSPDRFLEQDIMELMHKKDCLGSMPVIMGYNSAEGLAIVVKAKQKLEAYEDDLARLVPRNLVLDPQAPEAQEAASDIRAFFFNGQALSKENMDNLVDLFSDYHFSMDLQRAVEIHASCQTQSPLYFYRLDYVGGRNLYKKIFQNEDLRGVAHADDICYLFQMAGDETEMNRDDLMVTERLCEMWANFARDGKPSPIWKPVKKPHNGEPIQLDCLLIDRELKMCSNPDGERMDFWRSMYRRYRSENFEAVRAKL", "length": 562 }, "evidence": [ { "id": "HGNC:1863", "url": "https://alliancegenome.org/gene/HGNC:1863#orthology", "database": "AGR" }, { "id": "MGI:2148202", "url": "https://alliancegenome.org/gene/MGI:2148202#orthology", "database": "AGR" }, { "id": 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The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endoplasmic reticulum lumen", "input_participant_list": [ "R-ALL-5693702" ], "output_participant_list": [ "R-ALL-5693711", "R-ALL-5693712" ], "enzyme_list": [ "A1ZA98-1", "A0A0B4LHM3-1", "Q9W2F4-1", "A1ZA97-1", "Q9W4N5-1", "Q9Y141-1" ], "evidence": [ { "id": "R-DME-5693691", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-5693691" } ] }, { "id": "R-DME-8937442", "name": "CES3 hydrolyses CHEST to CHOL and LCFA(-)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, lipid droplet, transport vesicle membrane", "input_participant_list": [ "R-ALL-163579" ], "output_participant_list": [], "enzyme_list": [ "A1ZA98-1", "A0A0B4LHM3-1", "Q9W2F4-1", "A1ZA97-1", "Q9W4N5-1", "Q9Y141-1" ], "evidence": [ { "id": "R-DME-8937442", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8937442" } ] }, { "id": "R-DME-9619024", "name": "CES1 trimer hydrolyses ACEI pro-drugs to ACEIs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region", "input_participant_list": [], "output_participant_list": [ "R-ALL-140972" ], "enzyme_list": [ "A1ZA98-1", "A0A0B4LHM3-1", "Q9W2F4-1", "A1ZA97-1", "Q9W4N5-1", "Q9Y141-1" ], "evidence": [ { "id": "R-DME-9619024", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9619024" } ] }, { "id": "R-DME-9727567", "name": "CES1 hydrolyses sacubitril to sacubitrilat", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, lipid droplet", "input_participant_list": [ "R-ALL-9727597" ], "output_participant_list": [ "R-ALL-9727588" ], "enzyme_list": [ "A1ZA98-1", "A0A0B4LHM3-1", "Q9W2F4-1", "A1ZA97-1", "Q9W4N5-1", "Q9Y141-1" ], "evidence": [ { "id": "R-DME-9727567", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9727567" } ] }, { "id": "R-DME-9749647", "name": "CES2 hydrolyzes ASA-", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endoplasmic reticulum lumen", "input_participant_list": [ "R-ALL-9749582" ], "output_participant_list": [ "R-ALL-9749588", "R-ALL-9749593" ], "enzyme_list": [ "A1ZA98-1", "A0A0B4LHM3-1", "Q9W2F4-1", "A1ZA97-1", "Q9W4N5-1", "Q9Y141-1" ], "evidence": [ { "id": "R-DME-9749647", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9749647" } ] }, { "id": "R-DME-9749792", "name": "CES1,CES2 hydrolyze ASA- to ST", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. 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Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9Y162", "url": "https://www.uniprot.org/uniprotkb/Q9Y162" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9Y162", "url": "https://www.uniprot.org/uniprotkb/Q9Y162" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9Y162", "url": "https://www.uniprot.org/uniprotkb/Q9Y162" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9Y162", "url": "https://www.uniprot.org/uniprotkb/Q9Y162" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9Y162", "url": "https://www.uniprot.org/uniprotkb/Q9Y162" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9Y162", "url": "https://www.uniprot.org/uniprotkb/Q9Y162" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9Y162", "url": "https://www.uniprot.org/uniprotkb/Q9Y162" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9Y162", "url": "https://www.uniprot.org/uniprotkb/Q9Y162" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9Y162", "url": "https://www.uniprot.org/uniprotkb/Q9Y162" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9Y162", "url": "https://www.uniprot.org/uniprotkb/Q9Y162" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9Y162", "url": "https://www.uniprot.org/uniprotkb/Q9Y162" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG6842", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG6842", "resource": "KEGG Pathway" }, { "id": "R-DME-9668328", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9668328", "resource": "Reactome", "description": "Sealing of the nuclear envelope (NE) by ESCRT-III" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M3AP98-1", "protein_name": "vesicle-fusing ATPase", "gene_name": "vps4a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTTSTLQKAIELVTKATEEDKAKNYEEALRLYQHAVEYFLHAIKYEAHSDKAKESIRGKCMQYLDRAEKLKDYLKNKDKQGKKPVKETQSNDKSDSDSEGENPEKKKLQEHLMGAIVMEKPNVRWSDVAGLEGAKEALKEAVILPIKFPHLFTGKRTPWRGILLFGPPGTGKSYLAKAVATEANNSTFFSVSSSDLMSKWLGESEKLVKNLFDLARQHKPSIIFIDEVDSLCGSRNENESEAARRIKTEFLVQMQGVGNNNDGILVLGATNIPWVLDAAIRRRFEKRIYIPLPEEPARSAMFRLHLGNTPHSLTEADLRQLARKTDGYSGADISIIVRDALMQPVRKVQSATHFKKVRGPSRSNSAVIVDDLLTPCSPGDPEAIEMTWMDVPGDKLLEPIVCMSDMLRSLATTRPTVNTEDLLKVKKFTEDFGQEG", "length": 436 }, "evidence": [ { "id": "RGD:628810", "url": "https://alliancegenome.org/gene/RGD:628810#orthology", "database": "AGR" }, { "id": "MGI:1890520", "url": "https://alliancegenome.org/gene/MGI:1890520#orthology", "database": "AGR" }, { "id": "HGNC:13488", "url": "https://alliancegenome.org/gene/HGNC:13488#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060929-388", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-388#orthology", "database": "AGR" }, { "id": "FB:FBgn0283469", "url": "https://alliancegenome.org/gene/FB:FBgn0283469#orthology", "database": "AGR" }, { "id": "SGD:S000006377", "url": "https://alliancegenome.org/gene/SGD:S000006377#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58GK36-1", "protein_name": "vesicle-fusing ATPase", "gene_name": "vps4b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MYNPHSRSVGGGNAPIFVGLPNRHKTPEEEEEEVRVDACKTQVPLLRQLIHVFQKAIAIAQKASEEDQAGHFEEAIKSYHHAVKYFLHIIKREPQGKEGNQKIREKCKQYLDRVEELQDYLDKKEATSCCYESKAIDLANKASQEDKAENYEEALRLYQHAVQYFLHVVKYEAQGDKAKQSIRAKCAEYLDRAEKLKEYLKKKEKAPAKPVKESQSNDKGNESDGEEDPEKKKFQNQLSGAIVMEKPNIKWNDVAGLEGAKEALKEAVILPIKFPHLFTGKRTPWRGILLFGPPGTGKSYLAKAVATEANNSTFFSISSSDLVSKWLGESEKLVKSLFTLAREHKPSIIFIDEIDSLCGSRSENESEAARRIKTEFLVQMQGVGNDNEGILVLGATNIPWTLDSAIRRRFEKRIYIPLPEEHARSFMFKLNLGTTPNSLTESDFMTLGKKTDGYSGADISIIVRDALMQPVRKVQSATHFKQVRGPSRSDPNVIVDDLLTPCSPGDPQAKEMTWMEVPGEKLLEPIVSMSDMLRSLSNTKPTVNEQDLEKLKKFTEDFGQEG", "length": 562 }, "evidence": [ { "id": "MGI:1100499", "url": "https://alliancegenome.org/gene/MGI:1100499#orthology", "database": "AGR" }, { "id": "HGNC:10895", "url": "https://alliancegenome.org/gene/HGNC:10895#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1235", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1235#orthology", "database": "AGR" }, { "id": "FB:FBgn0283469", "url": "https://alliancegenome.org/gene/FB:FBgn0283469#orthology", "database": "AGR" }, { "id": "RGD:1305969", "url": "https://alliancegenome.org/gene/RGD:1305969#orthology", "database": "AGR" }, { "id": "SGD:S000006377", "url": "https://alliancegenome.org/gene/SGD:S000006377#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F7EZ84-1", "protein_name": "vesicle-fusing ATPase", "gene_name": "Vps4b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASTNTNLQKAIDLASKAAQEDKAGNYEEALQLYQHAVQYFLHVVKYEAQGDKAKQSIRAKCTEYLDRAEKLKEYLKKKEKKPQKPMKEEQSGPVDEKGNDSDGEAESDDPEKKKLQNQLQGAIVIERPNVKWSDVAGLEGAKEALKEAVILPIKFPHLFTGKRTPWRGILLFGPPGTGKSYLAKAVATEANNSTFFSISSSDLVSKWLGESEKLVKNLFQLARENKPSIIFIDEIDSLCGSRSENESEAARRIKTEFLVQMQGVGVDNDGILVLGATNIPWVLDSAIRRRFEKRIYIPLPEAHARAAMFRLHLGSTQNSLTEADFQELGRKTDGYSGADISIIVRDALMQPVRKVQSATHFKKVRGPSRADPNCIVNDLLTPCSPGDPGAIEMTWMDVPGDKLLEPVVSMWDMLRSLSSTKPTVNEQDLLKLKKFTEDFGQEG", "length": 444 }, "evidence": [ { "id": "MGI:1100499", "url": "https://alliancegenome.org/gene/MGI:1100499#orthology", "database": "AGR" }, { "id": "HGNC:10895", "url": "https://alliancegenome.org/gene/HGNC:10895#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1235", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1235#orthology", "database": "AGR" }, { "id": "FB:FBgn0283469", "url": "https://alliancegenome.org/gene/FB:FBgn0283469#orthology", "database": "AGR" }, { "id": "RGD:1305969", "url": "https://alliancegenome.org/gene/RGD:1305969#orthology", "database": "AGR" }, { "id": "SGD:S000006377", "url": "https://alliancegenome.org/gene/SGD:S000006377#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3I008-1", "protein_name": "vesicle-fusing ATPase", "gene_name": "Vps4a", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTTSTLQKAIDLVTKATEEDKAKNYEEALRLYQHAVEYFLHAIKYEAHSDKAKESIRAKCVQYLDRAEKLKDYLRNKEKHGKKPVKENQSEGKGSDSDSEGDNPEKKKLQEQLMGAVVMEKPNIRWNDVAGLEGAKEALKEAVILPIKFPHLFTGKRTPWRGILLFGPPGTGKSYLAKAVATEANNSTFFSVSSSDLMSKWLGESEKLVKNLFELARQHKPSIIFIDEVDSLCGSRNENESEAARRIKTEFLVQMQGVGNNNDGTLVLGATNIPWVLDSAIRRRFEKRIYIPLPEEAARAQMFRLHLGSTPHNLTDANIHELARKTEGYSGADISIIVRDSLMQPVRKVQSATHFKKVCGPSRTNPSVVIDDLLTPCSPGDPGAIEMTWMDVPGDKLLEPVVCMSDMLRSLATTRPTVNAEDLLKVKKFSEDFGQES", "length": 437 }, "evidence": [ { "id": "Q9Y162", "url": "https://omabrowser.org/oma/group/Q9Y162/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O75351-1", "protein_name": "Vacuolar protein sorting-associated protein 4B", "gene_name": "VPS4B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSTSPNLQKAIDLASKAAQEDKAGNYEEALQLYQHAVQYFLHVVKYEAQGDKAKQSIRAKCTEYLDRAEKLKEYLKNKEKKAQKPVKEGQPSPADEKGNDSDGEGESDDPEKKKLQNQLQGAIVIERPNVKWSDVAGLEGAKEALKEAVILPIKFPHLFTGKRTPWRGILLFGPPGTGKSYLAKAVATEANNSTFFSISSSDLVSKWLGESEKLVKNLFQLARENKPSIIFIDEIDSLCGSRSENESEAARRIKTEFLVQMQGVGVDNDGILVLGATNIPWVLDSAIRRRFEKRIYIPLPEPHARAAMFKLHLGTTQNSLTEADFRELGRKTDGYSGADISIIVRDALMQPVRKVQSATHFKKVRGPSRADPNHLVDDLLTPCSPGDPGAIEMTWMDVPGDKLLEPVVSMSDMLRSLSNTKPTVNEHDLLKLKKFTEDFGQEG", "length": 444 }, "evidence": [ { "id": "MGI:1100499", "url": "https://alliancegenome.org/gene/MGI:1100499#orthology", "database": "AGR" }, { "id": "HGNC:10895", "url": "https://alliancegenome.org/gene/HGNC:10895#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1235", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1235#orthology", "database": "AGR" }, { "id": "FB:FBgn0283469", "url": "https://alliancegenome.org/gene/FB:FBgn0283469#orthology", "database": "AGR" }, { "id": "RGD:1305969", "url": "https://alliancegenome.org/gene/RGD:1305969#orthology", "database": "AGR" }, { "id": "SGD:S000006377", "url": "https://alliancegenome.org/gene/SGD:S000006377#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P46467-1", "protein_name": "Vacuolar protein sorting-associated protein 4B", "gene_name": "Vps4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASTNTNLQKAIDLASKAAQEDKAGNYEEALQLYQHAVQYFLHVVKYEAQGDKAKQSIRAKCTEYLDRAEKLKEYLKKKEKKPQKPVKEEQSGPVDEKGNDSDGEAESDDPEKKKLQNQLQGAIVIERPNVKWSDVAGLEGAKEALKEAVILPIKFPHLFTGKRTPWRGILLFGPPGTGKSYLAKAVATEANNSTFFSISSSDLVSKWLGESEKLVKNLFQLARENKPSIIFIDEIDSLCGSRSENESEAARRIKTEFLVQMQGVGVDNDGILVLGATNIPWVLDSAIRRRFEKRIYIPLPEAHARAAMFRLHLGSTQNSLTEADFQELGRKTDGYSGADISIIVRDALMQPVRKVQSATHFKKVRGPSRADPNCIVNDLLTPCSPGDPGAIEMTWMDVPGDKLLEPVVSMWDMLRSLSSTKPTVNEQDLLKLKKFTEDFGQEG", "length": 444 }, "evidence": [ { "id": "MGI:1100499", "url": "https://alliancegenome.org/gene/MGI:1100499#orthology", "database": "AGR" }, { "id": "HGNC:10895", "url": "https://alliancegenome.org/gene/HGNC:10895#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1235", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1235#orthology", "database": "AGR" }, { "id": "FB:FBgn0283469", "url": "https://alliancegenome.org/gene/FB:FBgn0283469#orthology", "database": "AGR" }, { "id": "RGD:1305969", "url": "https://alliancegenome.org/gene/RGD:1305969#orthology", "database": "AGR" }, { "id": "SGD:S000006377", "url": "https://alliancegenome.org/gene/SGD:S000006377#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P52917-1", "protein_name": "Vacuolar protein sorting-associated protein 4", "gene_name": "VPS4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSTGDFLTKGIELVQKAIDLDTATQYEEAYTAYYNGLDYLMLALKYEKNPKSKDLIRAKFTEYLNRAEQLKKHLESEEANAAKKSPSAGSGSNGGNKKISQEEGEDNGGEDNKKLRGALSSAILSEKPNVKWEDVAGLEGAKEALKEAVILPVKFPHLFKGNRKPTSGILLYGPPGTGKSYLAKAVATEANSTFFSVSSSDLVSKWMGESEKLVKQLFAMARENKPSIIFIDEVDALTGTRGEGESEASRRIKTELLVQMNGVGNDSQGVLVLGATNIPWQLDSAIRRRFERRIYIPLPDLAARTTMFEINVGDTPCVLTKEDYRTLGAMTEGYSGSDIAVVVKDALMQPIRKIQSATHFKDVSTEDDETRKLTPCSPGDDGAIEMSWTDIEADELKEPDLTIKDFLKAIKSTRPTVNEDDLLKQEQFTRDFGQEGN", "length": 437 }, "evidence": [ { "id": "RGD:628810", "url": "https://alliancegenome.org/gene/RGD:628810#orthology", "database": "AGR" }, { "id": "MGI:1890520", "url": "https://alliancegenome.org/gene/MGI:1890520#orthology", "database": "AGR" }, { "id": "MGI:1100499", "url": "https://alliancegenome.org/gene/MGI:1100499#orthology", "database": "AGR" }, { "id": "HGNC:10895", "url": "https://alliancegenome.org/gene/HGNC:10895#orthology", "database": "AGR" }, { "id": "HGNC:13488", "url": "https://alliancegenome.org/gene/HGNC:13488#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1235", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1235#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060929-388", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-388#orthology", "database": "AGR" }, { "id": "FB:FBgn0283469", "url": "https://alliancegenome.org/gene/FB:FBgn0283469#orthology", "database": "AGR" }, { "id": "RGD:1305969", "url": "https://alliancegenome.org/gene/RGD:1305969#orthology", "database": "AGR" }, { "id": "SGD:S000006377", "url": "https://alliancegenome.org/gene/SGD:S000006377#orthology", "database": "AGR" }, { "id": "Q9Y162", "url": "https://omabrowser.org/oma/group/Q9Y162/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54PT2-1", "protein_name": "Vacuolar protein sorting-associated protein 4", "gene_name": "vps4", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGDVNFLQKAIQIVQQATEQDNAKNYAEAHRLYIQSLEWFTTALKYEKSERSKATIKAKTLEYLQRAEQLKEYLDKSKNKKPVAVGGNKSNSAGSANGAGKSAKEDDEDMDPEDKKRNDSLSSSIVTTKPNVKWDDVAGLYQAKEYLKEAVIFPIKFPQMFTGNRKPWKGILLYGPPGTGKSYLAKAVATEISSTFFSISPSDIVTKWLGDSEKLVKQLFEMAREKNNSVIFIDEVDSLCSSRNDQESESARRIKTEFLIQMNGVGNDSDGILVLAATNIPWGLDLAIRRRFEKRIYIGLPEPQARAKMFQIHIGSTPNTLVQADYKKLADLTEGYSGSDIGSLVKDAIMQPVRAVQCATHFKQIRAPSREDPSVMTDYVTPCSPGDPLAQEMTWMDIDPTKLKEPEITIADCLKSLRVIKPSVNKADLDRYVEFTNDFGQDGV", "length": 444 }, "evidence": [ { "id": "Q9Y162", "url": "https://omabrowser.org/oma/group/Q9Y162/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q793F9-1", "protein_name": "Vacuolar protein sorting-associated protein 4A", "gene_name": "Vps4a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTTSTLQKAIDLVTKATEEDKAKNYEEALRLYQHAVEYFLHAIKYEAHSDKAKESIRAKCMQYLDRAEKLKDYLRNKEKHGKKPVKENQSEGKGSDSDSEGDNPEKKKLQEQLMGAVVMEKPNIRWNDVAGLEGAKEALKEAVILPIKFPHLFTGKRTPWRGILLFGPPGTGKSYLAKAVATEANNSTFFSVSSSDLMSKWLGESEKLVKNLFELARQHKPSIIFIDEVDSLCGSRNENESEAARRIKTEFLVQMQGVGNNNDGTLVLGATNIPWVLDSAIRRRFEKRIYIPLPEEAARAQMFRLHLGSTPHNLTDANIHELARKTEGYSGADISIIVRDSLMQPVRKVQSATHFKKVCGPSRTNPSVMIDDLLTPCSPGDPGAIEMTWMDVPGDKLLEPVVCMSDMLRSLATTRPTVNADDLLKVKKFSEDFGQES", "length": 437 }, "evidence": [ { "id": "RGD:628810", "url": "https://alliancegenome.org/gene/RGD:628810#orthology", "database": "AGR" }, { "id": "MGI:1890520", "url": "https://alliancegenome.org/gene/MGI:1890520#orthology", "database": "AGR" }, { "id": "HGNC:13488", "url": "https://alliancegenome.org/gene/HGNC:13488#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060929-388", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-388#orthology", "database": "AGR" }, { "id": "FB:FBgn0283469", "url": "https://alliancegenome.org/gene/FB:FBgn0283469#orthology", "database": "AGR" }, { "id": "SGD:S000006377", "url": "https://alliancegenome.org/gene/SGD:S000006377#orthology", "database": "AGR" }, { "id": "Q9Y162", "url": "https://omabrowser.org/oma/group/Q9Y162/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8VEJ9-1", "protein_name": "Vacuolar protein sorting-associated protein 4A", "gene_name": "Vps4a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTTSTLQKAIDLVTKATEEDKAKNYEEALRLYQHAVEYFLHAIKYEAHSDKAKESIRAKCMQYLDRAEKLKDYLRNKEKHGKKPVKENQSEGKGSDSDSEGDNPEKKKLQEQLMGAVVMEKPNIRWNDVAGLEGAKEALKEAVILPIKFPHLFTGKRTPWRGILLFGPPGTGKSYLAKAVATEANNSTFFSVSSSDLMSKWLGESEKLVKNLFELARQHKPSIIFIDEVDSLCGSRNENESEAARRIKTEFLVQMQGVGNNNDGTLVLGATNIPWVLDSAIRRRFEKRIYIPLPEEAARAQMFRLHLGSTPHNLTDANIHELARKTEGYSGADISIIVRDSLMQPVRKVQSATHFKKVCGPSRTNPSVMIDDLLTPCSPGDPGAIEMTWMDVPGDKLLEPVVCMSDMLRSLATTRPTVNADDLLKVKKFSEDFGQES", "length": 437 }, "evidence": [ { "id": "RGD:628810", "url": "https://alliancegenome.org/gene/RGD:628810#orthology", "database": "AGR" }, { "id": "MGI:1890520", "url": "https://alliancegenome.org/gene/MGI:1890520#orthology", "database": "AGR" }, { "id": "HGNC:13488", "url": "https://alliancegenome.org/gene/HGNC:13488#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060929-388", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-388#orthology", "database": "AGR" }, { "id": "FB:FBgn0283469", "url": "https://alliancegenome.org/gene/FB:FBgn0283469#orthology", "database": "AGR" }, { "id": "SGD:S000006377", "url": "https://alliancegenome.org/gene/SGD:S000006377#orthology", "database": "AGR" }, { "id": "Q9Y162", "url": "https://omabrowser.org/oma/group/Q9Y162/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UN37-1", "protein_name": "Vacuolar protein sorting-associated protein 4A", "gene_name": "VPS4A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTTSTLQKAIDLVTKATEEDKAKNYEEALRLYQHAVEYFLHAIKYEAHSDKAKESIRAKCVQYLDRAEKLKDYLRSKEKHGKKPVKENQSEGKGSDSDSEGDNPEKKKLQEQLMGAVVMEKPNIRWNDVAGLEGAKEALKEAVILPIKFPHLFTGKRTPWRGILLFGPPGTGKSYLAKAVATEANNSTFFSVSSSDLMSKWLGESEKLVKNLFELARQHKPSIIFIDEVDSLCGSRNENESEAARRIKTEFLVQMQGVGNNNDGTLVLGATNIPWVLDSAIRRRFEKRIYIPLPEEAARAQMFRLHLGSTPHNLTDANIHELARKTEGYSGADISIIVRDSLMQPVRKVQSATHFKKVCGPSRTNPSMMIDDLLTPCSPGDPGAMEMTWMDVPGDKLLEPVVCMSDMLRSLATTRPTVNADDLLKVKKFSEDFGQES", "length": 437 }, "evidence": [ { "id": "RGD:628810", "url": "https://alliancegenome.org/gene/RGD:628810#orthology", "database": "AGR" }, { "id": "MGI:1890520", "url": "https://alliancegenome.org/gene/MGI:1890520#orthology", "database": "AGR" }, { "id": "HGNC:13488", "url": "https://alliancegenome.org/gene/HGNC:13488#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060929-388", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-388#orthology", "database": "AGR" }, { "id": "FB:FBgn0283469", "url": "https://alliancegenome.org/gene/FB:FBgn0283469#orthology", "database": "AGR" }, { "id": "SGD:S000006377", "url": "https://alliancegenome.org/gene/SGD:S000006377#orthology", "database": "AGR" }, { "id": "Q9Y162", "url": "https://omabrowser.org/oma/group/Q9Y162/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 16, "go_terms": [ { "name": "multivesicular body assembly", "id": "GO:0036258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036258", "evidence": [ { "database": "UniProtKB", "id": "Q9Y162", "url": "https://www.uniprot.org/uniprotkb/Q9Y162" } ], "pmid": "" }, { "name": "autophagosome maturation", "id": "GO:0097352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097352", "evidence": [ { "database": "UniProtKB", "id": "Q9Y162", "url": "https://www.uniprot.org/uniprotkb/Q9Y162" } ], "pmid": "" }, { "name": "protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway", "id": "GO:0043328", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043328", "evidence": [ { "database": "UniProtKB", "id": "Q9Y162", "url": "https://www.uniprot.org/uniprotkb/Q9Y162" } ], "pmid": "" }, { "name": "neuron remodeling", "id": "GO:0016322", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016322", "evidence": [ { "database": "UniProtKB", "id": "Q9Y162", "url": "https://www.uniprot.org/uniprotkb/Q9Y162" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q9Y162", "url": "https://www.uniprot.org/uniprotkb/Q9Y162" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "Q9Y162", "url": "https://www.uniprot.org/uniprotkb/Q9Y162" } ], "pmid": "" }, { "name": "positive regulation of epidermal growth factor receptor signaling pathway", "id": "GO:0045742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045742", "evidence": [ { "database": "UniProtKB", "id": "Q9Y162", "url": "https://www.uniprot.org/uniprotkb/Q9Y162" } ], "pmid": "" }, { "name": "endosomal transport", "id": "GO:0016197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016197", "evidence": [ { "database": "UniProtKB", "id": "Q9Y162", "url": "https://www.uniprot.org/uniprotkb/Q9Y162" } ], "pmid": "" }, { "name": "symbiont entry into host cell", "id": "GO:0046718", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046718", "evidence": [ { "database": "UniProtKB", "id": "Q9Y162", "url": "https://www.uniprot.org/uniprotkb/Q9Y162" } ], "pmid": "" }, { "name": "vacuole organization", "id": "GO:0007033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007033", "evidence": [ { "database": "UniProtKB", "id": "Q9Y162", "url": "https://www.uniprot.org/uniprotkb/Q9Y162" } ], "pmid": "" }, { "name": "establishment or maintenance of epithelial cell apical/basal polarity", "id": "GO:0045197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045197", "evidence": [ { "database": "UniProtKB", "id": "Q9Y162", "url": "https://www.uniprot.org/uniprotkb/Q9Y162" } ], "pmid": "" }, { "name": "membrane fission", "id": "GO:0090148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090148", "evidence": [ { "database": "UniProtKB", "id": "Q9Y162", "url": "https://www.uniprot.org/uniprotkb/Q9Y162" } ], "pmid": "" }, { "name": "ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway", "id": "GO:0090611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090611", "evidence": [ { "database": "UniProtKB", "id": "Q9Y162", "url": "https://www.uniprot.org/uniprotkb/Q9Y162" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway", "id": "GO:0043162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043162", "evidence": [ { "database": "UniProtKB", "id": "Q9Y162", "url": "https://www.uniprot.org/uniprotkb/Q9Y162" } ], "pmid": "" }, { "name": "R8 cell development", "id": "GO:0045463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045463", "evidence": [ { "database": "UniProtKB", "id": "Q9Y162", "url": "https://www.uniprot.org/uniprotkb/Q9Y162" } ], "pmid": "" }, { "name": "R8 cell-mediated photoreceptor organization", "id": "GO:0045470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045470", "evidence": [ { "database": "UniProtKB", "id": "Q9Y162", "url": "https://www.uniprot.org/uniprotkb/Q9Y162" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9Y162", "url": "https://www.uniprot.org/uniprotkb/Q9Y162" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "Q9Y162", "url": "https://www.uniprot.org/uniprotkb/Q9Y162" } ], "pmid": "" }, { "name": "ATP-dependent protein disaggregase activity", "id": "GO:0140545", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140545", "evidence": [ { "database": "UniProtKB", "id": "Q9Y162", "url": "https://www.uniprot.org/uniprotkb/Q9Y162" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9Y162", "url": "https://www.uniprot.org/uniprotkb/Q9Y162" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "Q9Y162", "url": "https://www.uniprot.org/uniprotkb/Q9Y162" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "Q9Y162", "url": "https://www.uniprot.org/uniprotkb/Q9Y162" } ], "pmid": "" }, { "name": "ESCRT IV complex", "id": "GO:1990621", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990621", "evidence": [ { "database": "UniProtKB", "id": "Q9Y162", "url": "https://www.uniprot.org/uniprotkb/Q9Y162" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 190, "end_pos": 192, "annotation": "n_glycosylation_sequon" }, { "start_pos": 246, "end_pos": 248, "annotation": "n_glycosylation_sequon" }, { "start_pos": 265, "end_pos": 267, "annotation": "n_glycosylation_sequon" }, { "start_pos": 314, "end_pos": 316, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-DME-9668389", "name": "VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, nuclear envelope", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q8I0P1-1", "Q9Y162-1" ], "evidence": [ { "id": "R-DME-9668389", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9668389" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "Q8I0P1", "gene_name": "spas", "activity": [ { "ec_number": "5.6.1.1", "activity": "n ATP + n H2O + a microtubule = n ADP + n phosphate + (n+1) alpha/beta tubulin heterodimers.", "evidence": [ { "id": "Q8I0P1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8I0P1" } ] }, { "ec_number": "5.6.1.1", "activity": "", "evidence": [ { "id": "Q8I0P1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8I0P1" } ] } ] }, { "uniprot_ac": "Q9Y162", "gene_name": "Vps4", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q9Y162", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9Y162" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "Q9Y162", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9Y162" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q9Y162", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9Y162" }, { "id": "SM00382", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00382" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AAA+ ATPase", "eco_id": "ECO_0000259", "start_pos": 164, "end_pos": 300, "start_aa": "Pro", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q9Y162", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9Y162" }, { "id": "SM00745", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00745" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MIT", "eco_id": "ECO_0000259", "start_pos": 3, "end_pos": 82, "start_aa": "Ala", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.6.4.6", "ec_name": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "3.6.4.6", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.6.4.6" }, { "id": "3.6.4.6", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.6.4.6" } ] } ], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 190, "end_pos": 192 }, { "start_pos": 246, "end_pos": 248 }, { "start_pos": 265, "end_pos": 267 }, { "start_pos": 314, "end_pos": 316 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { 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Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "X2J8R6", "url": "https://www.uniprot.org/uniprotkb/X2J8R6" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "X2J8R6", "url": "https://www.uniprot.org/uniprotkb/X2J8R6" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "X2J8R6", "url": "https://www.uniprot.org/uniprotkb/X2J8R6" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "X2J8R6", "url": "https://www.uniprot.org/uniprotkb/X2J8R6" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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"MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "HPC4", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, type 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "HPC5", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, type 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "HPC6", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer, hereditary, 7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "HPC7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer, hereditary, 7", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, type 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "HPC9", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "prostate cancer, hereditary, 10", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "HPC10", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "prostate cancer, hereditary, 10", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, 12", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the EHBP1 gene." }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "EHBP1 familial prostate cancer", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "familial prostate cancer caused by mutation in EHBP1", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, 12", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, type 12", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "HPC12", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, 13", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the MSMB gene." }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "MSMB familial prostate cancer", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "familial prostate cancer caused by mutation in MSMB", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, 13", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, type 13", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "HPC13", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "HPC11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "HPC14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "prostate cancer, hereditary, 15", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "HPC15", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "prostate cancer, hereditary, 15", "description": "" }, { "id": "MONDO:0700275", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0700275", "name": "prostate cancer, hereditary", "description": "An instance of prostate cancer that is caused by an inherited genomic modification in an individual. Familial prostate cancer (FPC) is a malignant tumor of the prostate with an early onset. FPC is either asymptomatic or causes mictionary symptoms, erectile dysfunction, bone pain, venous compression and infectious or inflammatory syndrome (for the metastatic forms). It is also characterized by familial antecedents." }, { "id": "MIM:601518", "resource": "MIM", "url": "https://www.omim.org/entry/601518", "name": "Prostate cancer, hereditary, 1", "description": "Prostate cancer, hereditary, 1" }, { "id": "MIM:610997", "resource": "MIM", "url": "https://www.omim.org/entry/610997", "name": "Prostate cancer, hereditary, 9", "description": "Prostate cancer, hereditary, 9" }, { "id": "MIM:611868", "resource": "MIM", "url": "https://www.omim.org/entry/611868", "name": "Prostate cancer, hereditary, 12", "description": "Prostate cancer, hereditary, 12" }, { "id": "MIM:611928", "resource": "MIM", "url": "https://www.omim.org/entry/611928", "name": "Prostate cancer, hereditary, 13", "description": "Prostate cancer, hereditary, 13" }, { "id": "MIM:611955", "resource": "MIM", "url": "https://www.omim.org/entry/611955", "name": "Prostate cancer, hereditary, 11", "description": "Prostate cancer, hereditary, 11" }, { "id": "MIM:176807", "resource": "MIM", "url": "https://www.omim.org/entry/176807", "name": "Prostate cancer", "description": "Prostate cancer" } ], "unlinked_id_list": [], "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ] }, { "disease_id": "DOID:10652", "recommended_name": { "id": "DOID:10652", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid." }, "synonyms": [ { "id": "DOID:10652", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10652", "name": "Alzheimer disease", "description": "" }, { "id": "DOID:10652", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10652", "name": "Alzheimers dementia", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ] }, { "disease_id": "DOID:10825", "recommended_name": { "id": "DOID:10825", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10825", "name": "essential hypertension", "description": "A hypertension with no known cause. It is the most common type of hypertension." }, "synonyms": [ { "id": "DOID:10825", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10825", "name": "idiopathic hypertension", "description": "" }, { "id": "DOID:10825", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10825", "name": "primary hypertension", "description": "" }, { "id": "MONDO:0007781", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007781", "name": "essential hypertension, genetic", "description": "An instance of essential hypertension that is caused by a modification of the individual's genome." }, { "id": "MONDO:0007781", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007781", "name": "blood pressure regulation QTL", "description": "" }, { "id": "MONDO:0007781", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007781", "name": "genetic essential hypertension", "description": "" }, { "id": "MONDO:0007781", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007781", "name": "hypertension, essential, salt-sensitive", "description": "" }, { "id": "MONDO:0007781", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007781", "name": "hypertension, essential, susceptibility to, 2", "description": "" }, { "id": "MONDO:0007781", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007781", "name": "hypertension, essential, susceptibility to, 3", "description": "" }, { "id": "MONDO:0007781", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007781", "name": "hypertension, essential, susceptibility to, 4", "description": "" }, { "id": "MONDO:0007781", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007781", "name": "hypertension, essential, susceptibility to, 5", "description": "" }, { "id": "MONDO:0007781", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007781", "name": "hypertension, essential, susceptibility to, 6", "description": "" }, { "id": "MONDO:0007781", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007781", "name": "hypertension, susceptibility to", "description": "" }, { "id": "MONDO:0007781", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007781", "name": "EHT", "description": "" }, { "id": "MONDO:0011384", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011384", "name": "hypertension, essential, susceptibility to, 1", "description": "" }, { "id": "MONDO:0011384", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011384", "name": "hypertension, essential, susceptibility to, 1", "description": "" }, { "id": "MONDO:0011384", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011384", "name": "hypertension, essential, susceptibility to, type 1", "description": "" }, { "id": "MONDO:0011440", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011440", "name": "hypertension, essential, susceptibility to, 2", "description": "" }, { "id": "MONDO:0011440", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011440", "name": "hypertension, essential, susceptibility to, 2", "description": "" }, { "id": "MONDO:0011440", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011440", "name": "hypertension, essential, susceptibility to, type 2", "description": "" }, { "id": "MONDO:0011815", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011815", "name": "hypertension, essential, susceptibility to, 3", "description": "" }, { "id": "MONDO:0011815", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011815", "name": "hypertension, essential, susceptibility to, 3", "description": "" }, { "id": "MONDO:0011815", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011815", "name": "hypertension, essential, susceptibility to, type 3", "description": "" }, { "id": "MONDO:0012109", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012109", "name": "hypertension, essential, susceptibility to, 4", "description": "" }, { "id": "MONDO:0012109", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012109", "name": "hypertension, essential, susceptibility to, 4", "description": "" }, { "id": "MONDO:0012109", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012109", "name": "hypertension, essential, susceptibility to, type 4", "description": "" }, { "id": "MONDO:0012458", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012458", "name": "hypertension, essential, susceptibility to, 5", "description": "" }, { "id": "MONDO:0012458", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012458", "name": "hypertension, essential, susceptibility to, 5", "description": "" }, { "id": "MONDO:0012458", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012458", "name": "hypertension, essential, susceptibility to, type 5", "description": "" }, { "id": "MONDO:0012459", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012459", "name": "hypertension, essential, susceptibility to, 6", "description": "" }, { "id": "MONDO:0012459", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012459", "name": "hypertension, essential, susceptibility to, 6", "description": "" }, { "id": "MONDO:0012459", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012459", "name": "hypertension, essential, susceptibility to, type 6", "description": "" }, { "id": "MONDO:0012587", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012587", "name": "hypertension, essential, susceptibility to, 7", "description": "" }, { "id": "MONDO:0012587", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012587", "name": "hypertension, essential, susceptibility to, 7", "description": "" }, { "id": "MONDO:0012587", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012587", "name": "hypertension, essential, susceptibility to, type 7", "description": "" }, { "id": "MONDO:0012599", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012599", "name": "hypertension, essential, susceptibility to, 8", "description": "" }, { "id": "MONDO:0012599", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012599", "name": "HYT8", "description": "" }, { "id": "MONDO:0012599", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012599", "name": "hypertension, essential, susceptibility to, 8", "description": "" }, { "id": "MIM:145500", "resource": "MIM", "url": "https://www.omim.org/entry/145500", "name": "Essential hypertension", "description": "Essential hypertension" } ], "unlinked_id_list": [], "evidence": [ { "id": "10825", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10825" } ] }, { "disease_id": "DOID:13580", "recommended_name": { "id": "DOID:13580", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13580", "name": "cholestasis", "description": "A bile duct disease that is characterized by where bile cannot flow from the liver to the duodenum." }, "synonyms": [ { "id": "DOID:13580", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13580", "name": "Obstruction of bile duct", "description": "" }, { "id": "DOID:13580", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13580", "name": "bile occlusion", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "13580", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13580" } ] }, { "disease_id": "DOID:1596", "recommended_name": { "id": "DOID:1596", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1596", "name": "depressive disorder", "description": "A mood disorder characterized by persistent sadness, emptiness, or irritability and decreased ability to function." }, "synonyms": [ { "id": "DOID:1596", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1596", "name": "mental depression", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "1596", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1596" } ] }, { "disease_id": "DOID:2030", "recommended_name": { "id": "DOID:2030", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2030", "name": "anxiety disorder", "description": "A cognitive disorder that involves an excessive, irrational dread of everyday situations." }, "synonyms": [ { "id": "DOID:2030", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2030", "name": "anxiety", "description": "" }, { "id": "DOID:2030", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2030", "name": "anxiety state", "description": "" }, { "id": "MONDO:0011918", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011918", "name": "anxiety", "description": "" }, { "id": "MONDO:0011918", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011918", "name": "anxiety", "description": "" }, { "id": "MONDO:0011918", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011918", "name": "anxiety-related personality traits", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "2030", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2030" } ] }, { "disease_id": "DOID:2987", "recommended_name": { "id": "DOID:2987", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2987", "name": "familial Mediterranean fever", "description": "An autoinflammatory disease characterized by recurrent episodes of fever and acute inflammation of the membranes lining the abdomen, joints and lungs; that has_material_basis_in mutations in the MEFV gene, which encodes the protein pyrin." }, "synonyms": [ { "id": "DOID:2987", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2987", "name": "benign paroxysmal peritonitis", "description": "" }, { "id": "DOID:2987", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2987", "name": "FMF", "description": "" }, { "id": "MONDO:0007601", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007601", "name": "familial Mediterranean fever, autosomal dominant", "description": "" }, { "id": "MONDO:0007601", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007601", "name": "familial Mediterranean fever, AD", "description": "" }, { "id": "MONDO:0007601", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007601", "name": "familial Mediterranean fever, autosomal dominant", "description": "" }, { "id": "MONDO:0009572", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009572", "name": "autosomal recessive familial Mediterranean fever", "description": "Autosomal recessive form of familial Mediterranean fever." }, { "id": "MONDO:0009572", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009572", "name": "autosomal recessive familial Mediterranean fever", "description": "" }, { "id": "MONDO:0009572", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009572", "name": "familial Mediterranean fever, AR", "description": "" }, { "id": "MONDO:0009572", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009572", "name": "familial Mediterranean fever, autosomal recessive", "description": "" }, { "id": "MONDO:0009572", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009572", "name": "FMF", "description": "" }, { "id": "MONDO:0009572", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009572", "name": "familial Mediterranean fever", "description": "" }, { "id": "MIM:134610", "resource": "MIM", "url": "https://www.omim.org/entry/134610", "name": "Familial Mediterranean fever, autosomal dominant", "description": "Familial Mediterranean fever, autosomal dominant" }, { "id": "MIM:249100", "resource": "MIM", "url": "https://www.omim.org/entry/249100", "name": "Familial Mediterranean fever, autosomal recessive", "description": "Familial Mediterranean fever, autosomal recessive" } ], "unlinked_id_list": [], "evidence": [ { "id": "2987", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2987" } ] }, { "disease_id": "DOID:5082", "recommended_name": { "id": "DOID:5082", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5082", "name": "liver cirrhosis", "description": "" }, "synonyms": [ { "id": "DOID:5082", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5082", "name": "Cirrhosis", "description": "" }, { "id": "DOID:5082", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5082", "name": "cirrhosis of liver", "description": "" }, { "id": "MONDO:0005155", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005155", "name": "cirrhosis of liver", "description": "A disorder characterized by replacement of the liver parenchyma with fibrous tissue and regenerative nodules. It is usually caused by alcoholism, hepatitis B, and hepatitis C. Complications include the development of ascites, esophageal varices, bleeding, and hepatic encephalopathy." }, { "id": "MONDO:0005155", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005155", "name": "cirrhosis", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "5082", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5082" } ] }, { "disease_id": "DOID:5773", "recommended_name": { "id": "DOID:5773", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5773", "name": "oral submucous fibrosis", "description": "A mouth disease that is characterized by juxta-epithelial inflammatory reaction and progressive fibrosis of the submucosal tissues." }, "synonyms": [ { "id": "DOID:5773", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5773", "name": "Oral cavity Submucous Fibrosis", "description": "" }, { "id": "DOID:5773", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5773", "name": "Oral submucosal fibrosis", "description": "" }, { "id": "DOID:5773", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5773", "name": "Oral submucosal fibrosis, including of tongue", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "5773", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5773" } ] }, { "disease_id": "DOID:783", "recommended_name": { "id": "DOID:783", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:783", "name": "end stage renal disease", "description": "A chronic kidney disease is characterized by non-functioning kidneys, as the final stage in chronic kidney disease." }, "synonyms": [ { "id": "DOID:783", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:783", "name": "end stage renal failure", "description": "" }, { "id": "DOID:783", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:783", "name": "end-stage kidney disease", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "783", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:783" } ] }, { "disease_id": "DOID:8552", "recommended_name": { "id": "DOID:8552", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8552", "name": "chronic myeloid leukemia", "description": "A myeloid leukemia that is characterized by over production of white blood cells." }, "synonyms": [ { "id": "DOID:8552", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8552", "name": "CML", "description": "" }, { "id": "DOID:8552", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8552", "name": "CML - chronic Myelogenous Leukemia", "description": "" }, { "id": "DOID:8552", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8552", "name": "Myeloid Leukemia, chronic", "description": "" }, { "id": "DOID:8552", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8552", "name": "chronic granulocytic leukaemia", "description": "" }, { "id": "DOID:8552", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8552", "name": "chronic granulocytic leukemia", "description": "" }, { "id": "DOID:8552", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8552", "name": "chronic myelogenous leukaemia", "description": "" }, { "id": "DOID:8552", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8552", "name": "chronic myelogenous leukemia", "description": "" }, { "id": "DOID:8552", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8552", "name": "chronic myeloid leukaemia", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "chronic myeloid leukemia", "description": "A chronic myeloproliferative neoplasm characterized by the expression of the BCR-ABL1 fusion gene. It presents with neutrophilic leukocytosis. It can appear at any age, but it mostly affects middle aged and older individuals. Patients usually present with fatigue, weight loss, anemia, night sweats, and splenomegaly. If untreated, it follows a biphasic or triphasic natural course; an initial indolent chronic phase which is followed by an accelerated phase, a blast phase, or both. Allogeneic stem cell transplantation and tyrosine kinase inhibitors delay disease progression and prolong overall survival." }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "BCR-ABL Positive chronic myelogenous leukaemia", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "BCR-ABL Positive chronic myelogenous leukemia", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "CML", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "CML - chronic myelogenous leukaemia", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "CML - chronic myelogenous leukemia", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "chronic granulocytic leukemia", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "chronic myelocytic leukaemia", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "chronic myelocytic leukemia", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "chronic myelogenous leukaemia (CML)", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "chronic myelogenous leukemia", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "chronic myelogenous leukemia (CML)", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "chronic myelogenous leukemia, BCR-ABL1 Positive", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "chronic myelogenous leukemias", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "chronic myeloid leukemia", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "hematopoeitic - chronic myelocytic leukaemia (CML)", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "hematopoeitic - chronic myelocytic leukemia (CML)", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "leukimia, chronic myeloid", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "myeloid leukemia, chronic", "description": "" }, { "id": "MIM:608232", "resource": "MIM", "url": "https://www.omim.org/entry/608232", "name": "Leukemia, chronic myeloid, atypical", "description": "Leukemia, chronic myeloid, atypical" } ], "unlinked_id_list": [], "evidence": [ { "id": "8552", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8552" } ] }, { "disease_id": "DOID:9952", "recommended_name": { "id": "DOID:9952", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9952", "name": "acute lymphoblastic leukemia", "description": "A acute leukemia that is characterized by over production of lymphoblasts." }, "synonyms": [ { "id": "DOID:9952", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9952", "name": "acute lymphoblastic leukaemia", "description": "" }, { "id": "DOID:9952", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9952", "name": "acute lymphocytic leukaemia", "description": "" }, { "id": "DOID:9952", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9952", "name": "ALL", "description": "" }, { "id": "DOID:9952", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9952", "name": "precursor lymphoblastic lymphoma/leukemia", "description": "" }, { "id": "MONDO:0009539", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009539", "name": "lymphoblastic leukemia, acute, with lymphomatous features", "description": "" }, { "id": "MONDO:0009539", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009539", "name": "leukemia, acute lymphoblastic", "description": "" }, { "id": "MONDO:0009539", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009539", "name": "lymphoblastic leukemia, acute, with lymphomatous features", "description": "" }, { "id": "MONDO:0009539", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009539", "name": "lall", "description": "" }, { "id": "MONDO:0013108", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013108", "name": "leukemia, acute lymphocytic, susceptibility to, 1", "description": "" }, { "id": "MONDO:0013108", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013108", "name": "T-cell acute lymphoblastic leukemia, somatic", "description": "" }, { "id": "MONDO:0013108", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013108", "name": "leukemia, T-cell acute lymphoblastic, somatic", "description": "" }, { "id": "MONDO:0013108", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013108", "name": 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"MIM", "url": "https://www.omim.org/entry/613065", "name": "Leukemia, acute lymphoblastic", "description": "Leukemia, acute lymphoblastic" } ], "unlinked_id_list": [ "DOID:0080638", "DOID:5604" ], "evidence": [ { "id": "9952", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9952" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "X2J9F6", "url": "https://www.uniprot.org/uniprotkb/X2J9F6" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Cyp6a16", "url": "https://www.uniprot.org/uniprotkb/X2J9F6", "locus": { "chromosome": "2L", "start_pos": 5620615, "end_pos": 5623762, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0031726", "url": "https://www.ensemblgenomes.org/id/FBgn0031726" } ] } } ], "crossref": [ { "id": "FB:FBgn0031726", "url": "https://alliancegenome.org/gene/FB:FBgn0031726", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0031726", "url": "https://bgee.org/?page=gene&gene_id=FBgn0031726", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11056", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11056", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0031726", "url": "https://flybase.org/reports/FBgn0031726", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "19836250", "url": "https://www.ncbi.nlm.nih.gov/gene/19836250", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002402", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002402", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017972", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017972", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036396", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036396", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050476", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050476", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG7249", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG7249", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YMFSTIT", "url": "https://omabrowser.org/oma/group/YMFSTIT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "X2J9F6", "url": "https://www.orthodb.org/?gene=X2J9F6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24292", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24292", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24292:SF100", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24292:SF100", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00067", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00067", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001285631", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285631", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "X2J9F6", "url": "https://www.uniprot.org/uniprotkb/X2J9F6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "X2J9F6-1", "url": "https://www.uniprot.org/uniprotkb/X2J9F6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDFTLLLLTSLLSFLLGYLRYRFTYWELRGIPQLRPHFLFGHFFRLQSVHYSELLQETYDAFRGSAKVAGTYVFLRPMAVVLDLDLVKAVLIRDFNNFVDRRSFHGDPLTANLFNLQGEEWRNLRTKLSPTFTSGKMKYMFGTVSTVAQQLGGTFDELVGSQGAVLELHDLMARYTTDVIGSCAFGTECSSLREPQAEFRQVGRRIFRNSNRSIRWRIFKMTYLSSLAKLGLPVRILHPDITKFFNRIVRETVELRERENIRRNDFMDLLLDLRRQENGKGLTMEQMAAQAFVFFVAGFETSSSNMSYALFELAKNQDVQQKLRMEINDSIGKHGKLTYEAMMEMPYLDQTITETLRKYPALSSLTRLASEDYEIPSPDGGDPVVLEKGTSVHIPVLAIHYDPEVYPEPHEFRPERFAPDACRERHPTAFLGFGDGPRNCIGLRFGRMQVKVGLITLLRRFRFSLPPGSPTQLKVTKRNLILLPSDGVRLQVDPVESRLM", "length": 500, "header": "tr|X2J9F6-1|X2J9F6_DROME Isoform 1 of Cytochrome P450 6a16, isoform C OS=Drosophila melanogaster OX=7227 GN=Cyp6a16 PE=3 SV=1 CANONICAL=X2J9F6-1" }, "isoforms": [ { "isoform_ac": "X2J9F6-1", "url": "https://www.uniprot.org/uniprotkb/X2J9F6/entry#X2J9F6-1", "sequence": { "sequence": "MDFTLLLLTSLLSFLLGYLRYRFTYWELRGIPQLRPHFLFGHFFRLQSVHYSELLQETYDAFRGSAKVAGTYVFLRPMAVVLDLDLVKAVLIRDFNNFVDRRSFHGDPLTANLFNLQGEEWRNLRTKLSPTFTSGKMKYMFGTVSTVAQQLGGTFDELVGSQGAVLELHDLMARYTTDVIGSCAFGTECSSLREPQAEFRQVGRRIFRNSNRSIRWRIFKMTYLSSLAKLGLPVRILHPDITKFFNRIVRETVELRERENIRRNDFMDLLLDLRRQENGKGLTMEQMAAQAFVFFVAGFETSSSNMSYALFELAKNQDVQQKLRMEINDSIGKHGKLTYEAMMEMPYLDQTITETLRKYPALSSLTRLASEDYEIPSPDGGDPVVLEKGTSVHIPVLAIHYDPEVYPEPHEFRPERFAPDACRERHPTAFLGFGDGPRNCIGLRFGRMQVKVGLITLLRRFRFSLPPGSPTQLKVTKRNLILLPSDGVRLQVDPVESRLM", "length": 500, "header": "tr|X2J9F6-1|X2J9F6_DROME Isoform 1 of Cytochrome P450 6a16, isoform C OS=Drosophila melanogaster OX=7227 GN=Cyp6a16 PE=3 SV=1 CANONICAL=X2J9F6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "X2J9F6", "url": "https://www.uniprot.org/uniprotkb/X2J9F6" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "X2J9F6", "url": "https://www.uniprot.org/uniprotkb/X2J9F6" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "X2J9F6", "url": "https://www.uniprot.org/uniprotkb/X2J9F6" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "X2J9F6", "url": "https://www.uniprot.org/uniprotkb/X2J9F6" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "X2J9F6", "url": "https://www.uniprot.org/uniprotkb/X2J9F6" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "X2J9F6", "url": "https://www.uniprot.org/uniprotkb/X2J9F6" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "X2J9F6", "url": "https://www.uniprot.org/uniprotkb/X2J9F6" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "X2J9F6", "url": "https://www.uniprot.org/uniprotkb/X2J9F6" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "X2J9F6", "url": "https://www.uniprot.org/uniprotkb/X2J9F6" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "X2J9F6", "url": "https://www.uniprot.org/uniprotkb/X2J9F6" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "X2J9F6", "url": "https://www.uniprot.org/uniprotkb/X2J9F6" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG7249", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG7249", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A2U8U1P3-1", "protein_name": "Cytochrome P450 9f3", "gene_name": "Cyp9f3", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLWEFLALFAIATALFYRWASANNDFFKDRGIAYEKPVLYLGNMAGMFLRKRAMLDIVCDLYTKGGSGKFFGIFAQRQPLLMVRDPDLIKQITIKDFDHFINHRNEFDTSSDDDPHDMSNLFSSSLFSMRDARWKDMRSTLSPAFTGSKMRQMFQLMNQVAKEAVDCLKQDDSRVQENELDMKDYCTRFTNDVIASTAFGLQVNSFKDRENTFYQMGKKLTTFTFLQNMKFILLFALKSLNKILKVEIFDRKSTQYFVRLVLDAMKYRQEHNIVRPDMINMLMEARGIIQTEKTKASAVREWSDRDIVAQCFVFFFAGFETSAVLMCFTAHELMENQDVQQRLYEEVQQVDQDLEGKELKYLDQVVSEVLRKWPPAIAFDRECNKEAKAVIYYLLKDYRFAPAKKSCIPLELISSGFQLSPKGGFWIKLVQRN", "length": 433 }, "evidence": [ { "id": "RGD:628709", "url": "https://alliancegenome.org/gene/RGD:628709#orthology", "database": "AGR" }, { "id": "HGNC:2638", "url": "https://alliancegenome.org/gene/HGNC:2638#orthology", "database": "AGR" }, { "id": "HGNC:2637", "url": "https://alliancegenome.org/gene/HGNC:2637#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050604-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050604-1#orthology", "database": "AGR" }, { "id": "RGD:1595919", "url": "https://alliancegenome.org/gene/RGD:1595919#orthology", "database": "AGR" }, { "id": "RGD:708379", "url": "https://alliancegenome.org/gene/RGD:708379#orthology", "database": "AGR" }, { "id": "RGD:708392", "url": "https://alliancegenome.org/gene/RGD:708392#orthology", "database": "AGR" }, { "id": "RGD:628626", "url": "https://alliancegenome.org/gene/RGD:628626#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A0A8M1N818-1", "protein_name": "unspecific monooxygenase", "gene_name": "cyp3a65", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFFSAETWTLLAFLVALLVIYGSWPHRYFKKLGIPGPKTIPFFGTMLRYKDGFHVFDMDCFEKYGRIWGIYDGRQPVLCIMDQTIIKTVLIKECYSLFTNRRNFRLNGALYDAVSIAEDDDWRRIRSVLSPSFTSGRLKEMFGIMKKHSHILVDSMGKTAKRGESADIKEFFGAYSMDVVTSTAFSVDIDSLNNPKDPFVTNIKKMLKFDLLNPLFLLIAFFPFMAPVLEKMDFALFPTSVTDFFYAALQKIKSDRDTKTVAKDNTKKRVDFLQLMVDSQTGVKHKSDGEHTEKGLSDHEILSQSMIFIFAGYETSSSTLSFLFYNLATNPETMKKLQEEIDETFPNQAPVDYETLMSMDYLDAALSESLRLYPVAARLERVCKKTVEINGLLIPKDLVVMVPTYALHRDPDYWSEPESFKPERFTKGNKESIDPYMYMPFGLGPRNCIGMRFAQVTMKLAIVEILQRFDVSVCDETQVPLELGFNGLLSPKDPIKLKLQPRKLSQSPDVCNNNQKS", "length": 517 }, "evidence": [ { "id": "FB:FBgn0031726", "url": "https://alliancegenome.org/gene/FB:FBgn0031726#orthology", "database": "AGR" }, { "id": "RGD:628709", "url": "https://alliancegenome.org/gene/RGD:628709#orthology", "database": "AGR" }, { "id": "HGNC:2638", "url": "https://alliancegenome.org/gene/HGNC:2638#orthology", "database": "AGR" }, { "id": "HGNC:2637", "url": "https://alliancegenome.org/gene/HGNC:2637#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050604-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050604-1#orthology", "database": "AGR" }, { "id": "RGD:1595919", "url": "https://alliancegenome.org/gene/RGD:1595919#orthology", "database": "AGR" }, { "id": "RGD:708379", "url": "https://alliancegenome.org/gene/RGD:708379#orthology", "database": "AGR" }, { "id": "RGD:708392", "url": "https://alliancegenome.org/gene/RGD:708392#orthology", "database": "AGR" }, { "id": "RGD:628626", "url": "https://alliancegenome.org/gene/RGD:628626#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3YYZ0-1", "protein_name": "Cytochrome P450 3A", "gene_name": "Cyp3a57", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MELIPNLSIQTWVLLVTSLVFFYIYGTYSHGLFKKLGIPGPKPLPLFGNIINYLDGMWKFDDDCYKKYGKIWGFYEGPQPILAIMDPEIIKIVLVKECYSVFTNRRPFGPVGFLKKSITISEDEEWKRLRTLLSPTFTSSKLKEMFPIMRQYGDILVRNLRREEEKEEPINMKDIFGAYSMDVITGTSCGVNIDSLNNPQDPFVQKIKKILKFKFFDPFLLSVVLFPFLTPIYEMLNLSIFPRQSMNFFKKFVKKMKKDRLDYNQKNRVDFLQLMMNTQNSKGQESLKALSDLEMAAQTLIFIFGGYDGTSTSISFIMYELATHPDVQKKLQDEIDRALPNKAPVTYDALMDMEYLDMVVNESLRLYPVVSRIDRFSKKDVEIHGVFIPKGTIVMIPIYPLHRDPEYWPEPEDFCPERFSKENKGNIDPYIYMPFGNGPRNCIGMRFALISVKLAVTGVLQNFTVQPCEETQIPVKISRQPIFRPEKPIILKFVSRDKPRTGP", "length": 503 }, "evidence": [ { "id": "RGD:628709", "url": "https://alliancegenome.org/gene/RGD:628709#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050604-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050604-1#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z2W7-1", "protein_name": "Cytochrome P450 3A", "gene_name": "Cyp3a59", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MELIPNLSIETWVLLVTSLVFFYIYGTYSHGLFKKLGIPGPKPLPLFGTIFNYFDGMWKFDEDCYKKYGKIWGFYVGPKPILAIMDPEIIKIVLVKECYSVFTNRPTLGPVGFLKKSITISEDEEWKRLRTLLSPTFTSGKLKEMFPIMRQYGDILVRNLRREEEKGEPINMKDIFGAYSMDVITGTSFGVNIDSLNNPQNPFVQKTKKILKFKIFDPFLLSTILFPFLTPIYEMLNLSIFPRDSMNFFKKFVKRMKKERLASKQKNRVDFLQLMMNTQNSKGQESQKALSDLEMAAQAVIFIFGGYDATSTSISLIMYELATHPDVQKKLQDEIDRTLPNKAPVTYDALMDMEYLDMVVNESLRLYPTAIRLERVSKKDVEINGVFIPKGTVVMIPIYPLHRNPEYWPEPQEFCPGRFSKENEGNIDPYIYMPFGNGPRNCLDMRFALISMKLAVIGVLQNFTVQPCEETQIPLKISREPVFQPEKPIILKVVSRDKPRTAS", "length": 503 }, "evidence": [ { "id": "RGD:628709", "url": "https://alliancegenome.org/gene/RGD:628709#orthology", "database": "AGR" }, { "id": "HGNC:2638", "url": "https://alliancegenome.org/gene/HGNC:2638#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050604-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050604-1#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7F0U1-1", "protein_name": "Cytochrome P450 3A", "gene_name": "Cyp3a62", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSMSSCRRIAVSLLCALPSPFCRSWMISGTEWAGSLGLSRIFLPYLSLTVPGKELMTSDMIICFTSLVSSIQSNAARRTRYGTSTHGNFKKLGISGPKPLPFVGNILAYRHGFWEFDRHCHKKYGDIWGFYEGRQPILAITDPDIIKTVLVKECYSTFTNRRSFGPAGILKKAITLSEDEEWKRLRTLLSPTFTSGKLKEMFPIINQYADLLVKNVKHEAEKGNPITMKDIFGAYSMDVITGTSFGVNVDSLNNPQNPFVQKVKKLLKFNFLDPFFLSVILFPFLTPVFEAFDITVFPKDVMKFFRTSVERMKENRMQEKVKQRLDFLQLMINSQSSGDKESHQGLTDVEIVAQSIFFIFAGYETTSSALSFALYLLATHPDLQKKLQDEIDAALPNKAPVTYDVLVEMEYLDMVLNETLRLFPVGGRLERVCKKDVEINGVFIPKGTVVMVPTFALHKDPKCWPEPEEFCPERFRKKNQDSINPYIYLPFGNGPRNCIGMRFALMNMKIALVRVLQNFSFGPCKETQIPLKLRKKGFFQPEKPIILRAVSRD", "length": 554 }, "evidence": [ { "id": "FB:FBgn0031726", "url": "https://alliancegenome.org/gene/FB:FBgn0031726#orthology", "database": "AGR" }, { "id": "HGNC:2637", "url": "https://alliancegenome.org/gene/HGNC:2637#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050604-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050604-1#orthology", "database": "AGR" }, { "id": "RGD:1595919", "url": "https://alliancegenome.org/gene/RGD:1595919#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O09158-1", "protein_name": "Cytochrome P450 3A25", "gene_name": "Cyp3a25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MELIPNLSIETWVLLVTSLVLFYIYGTYSHGLFKKLGIPGPKPLPLLGTIFNYYDGMWKFDEDCYKKYGKIWGFYEGPQPILAIMDPEIIKIVLVKECYSVFTNRRFFGPVGFMKKAITISEDEEWKRLRTLLSPTFTSGKLKEMFPIMRQYGDILVRNLRREEEKGEPISMKDIFGAYSMDVITGTSFGVNVDSLNNPQDPFVQKAKKILKFKIFDPFLLSIILFPFLTPIYEMLNFSIFPRDSMNFFKKFVKRMKKERLASNQKNRVDFLQLMMNTQNSKGQESQKALSDLEMAAQAVIFIFGGYDATSTSISLIMYELATHPDVQKKLQDEIDRTLPNKAPVTYDALMDMEYLDMVVNESLRLYPIAIRLERVSKKDVEINGVFIPKGTVVMIPIYPLHRNPEYWPEPQEFCPERFSKENKGNIDPYIYMPFGNGPRNCIGMRFALISIKLAVIGVLQNFTVQPCEETQIPLKISREPIFQPEKPIILKVVSRDKPRTGS", "length": 503 }, "evidence": [ { "id": "RGD:628709", "url": "https://alliancegenome.org/gene/RGD:628709#orthology", "database": "AGR" }, { "id": "HGNC:2638", "url": "https://alliancegenome.org/gene/HGNC:2638#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050604-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050604-1#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P05183-1", "protein_name": "Cytochrome P450 3A2", "gene_name": "Cyp3a2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLLSALTLETWVLLAVILVLLYRLGTHRHGIFKKQGIPGPKPLPFLGTVLNYYKGLGRFDMECYKKYGKIWGLFDGQTPVFAIMDTEMIKNVLVKECFSVFTNRRDFGPVGIMGKAVSVAKDEEWKRYRALLSPTFTSGRLKEMFPIIEQYGDILVKYLKQEAETGKPVTMKKVFGAYSMDVITSTSFGVNVDSLNNPKDPFVEKTKKLLRFDFFDPLFLSVVLFPFLTPIYEMLNICMFPKDSIAFFQKFVHRIKETRLDSKHKHRVDFLQLMLNAHNNSKDEVSHKALSDVEIIAQSVIFIFAGYETTSSTLSFVLYFLATHPDIQKKLQEEIDGALPSKAPPTYDIVMEMEYLDMVLNETLRLYPIGNRLERVCKKDIELDGLFIPKGSVVTIPTYALHHDPQHWPKPEEFHPERFSKENKGSIDPYVYLPFGNGPRNCIGMRFALMNMKLALTKVLQNFSFQPCKETQIPLKLSRQAILEPEKPIVLKVLPRDAVINGA", "length": 504 }, "evidence": [ { "id": "FB:FBgn0031726", "url": "https://alliancegenome.org/gene/FB:FBgn0031726#orthology", "database": "AGR" }, { "id": "HGNC:2638", "url": "https://alliancegenome.org/gene/HGNC:2638#orthology", "database": "AGR" }, { "id": "HGNC:2637", "url": "https://alliancegenome.org/gene/HGNC:2637#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050604-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050604-1#orthology", "database": "AGR" }, { "id": "RGD:708379", "url": "https://alliancegenome.org/gene/RGD:708379#orthology", "database": "AGR" }, { "id": "RGD:628626", "url": "https://alliancegenome.org/gene/RGD:628626#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P08684-1", "protein_name": "Cytochrome P450 3A4", "gene_name": "CYP3A4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALIPDLAMETWLLLAVSLVLLYLYGTHSHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESRDGTVSGA", "length": 503 }, "evidence": [ { "id": "FB:FBgn0031726", "url": "https://alliancegenome.org/gene/FB:FBgn0031726#orthology", "database": "AGR" }, { "id": "HGNC:2637", "url": "https://alliancegenome.org/gene/HGNC:2637#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050604-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050604-1#orthology", "database": "AGR" }, { "id": "RGD:1595919", "url": "https://alliancegenome.org/gene/RGD:1595919#orthology", "database": "AGR" }, { "id": "RGD:708379", "url": "https://alliancegenome.org/gene/RGD:708379#orthology", "database": "AGR" }, { "id": "RGD:708392", "url": "https://alliancegenome.org/gene/RGD:708392#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P10614-1", "protein_name": "Lanosterol 14-alpha demethylase CYP51", "gene_name": "ERG11", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSATKSIVGEALEYVNIGLSHFLALPLAQRISLIIIIPFIYNIVWQLLYSLRKDRPPLVFYWIPWVGSAVVYGMKPYEFFEECQKKYGDIFSFVLLGRVMTVYLGPKGHEFVFNAKLADVSAEAAYAHLTTPVFGKGVIYDCPNSRLMEQKKFVKGALTKEAFKSYVPLIAEEVYKYFRDSKNFRLNERTTGTIDVMVTQPEMTIFTASRSLLGKEMRAKLDTDFAYLYSDLDKGFTPINFVFPNLPLEHYRKRDHAQKAISGTYMSLIKERRKNNDIQDRDLIDSLMKNSTYKDGVKMTDQEIANLLIGVLMGGQHTSAATSAWILLHLAERPDVQQELYEEQMRVLDGGKKELTYDLLQEMPLLNQTIKETLRMHHPLHSLFRKVMKDMHVPNTSYVIPAGYHVLVSPGYTHLRDEYFPNAHQFNIHRWNKDSASSYSVGEEVDYGFGAISKGVSSPYLPFGGGRHRCIGEHFAYCQLGVLMSIFIRTLKWHYPEGKTVPPPDFTSMVTLPTGPAKIIWEKRNPEQKI", "length": 530 }, "evidence": [ { "id": "FB:FBgn0031726", "url": "https://alliancegenome.org/gene/FB:FBgn0031726#orthology", "database": "AGR" }, { "id": "SGD:S000001049", "url": "https://alliancegenome.org/gene/SGD:S000001049#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P20815-1", "protein_name": "Cytochrome P450 3A5", "gene_name": "CYP3A5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDLIPNLAVETWLLLAVSLVLLYLYGTRTHGLFKRLGIPGPTPLPLLGNVLSYRQGLWKFDTECYKKYGKMWGTYEGQLPVLAITDPDVIRTVLVKECYSVFTNRRSLGPVGFMKSAISLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGAYSMDVITGTSFGVNIDSLNNPQDPFVESTKKFLKFGFLDPLFLSIILFPFLTPVFEALNVSLFPKDTINFLSKSVNRMKKSRLNDKQKHRLDFLQLMIDSQNSKETESHKALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLDTQGLLQPEKPIVLKVDSRDGTLSGE", "length": 502 }, "evidence": [ { "id": "FB:FBgn0031726", "url": "https://alliancegenome.org/gene/FB:FBgn0031726#orthology", "database": "AGR" }, { "id": "HGNC:2638", "url": "https://alliancegenome.org/gene/HGNC:2638#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050604-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050604-1#orthology", "database": "AGR" }, { "id": "RGD:708379", "url": "https://alliancegenome.org/gene/RGD:708379#orthology", "database": "AGR" }, { "id": "RGD:708392", "url": "https://alliancegenome.org/gene/RGD:708392#orthology", "database": "AGR" }, { "id": "RGD:628626", "url": "https://alliancegenome.org/gene/RGD:628626#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P24462-1", "protein_name": "Cytochrome P450 3A7", "gene_name": "CYP3A7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDLIPNLAVETWLLLAVSLILLYLYGTRTHGLFKKLGIPGPTPLPFLGNALSFRKGYWTFDMECYKKYRKVWGIYDCQQPMLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKNAISIAEDEEWKRIRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGAYSMDVITSTSFGVSIDSLNNPQDPFVENTKKLLRFNPLDPFVLSIKVFPFLTPILEALNITVFPRKVISFLTKSVKQIKEGRLKETQKHRVDFLQLMIDSQNSKDSETHKALSDLELMAQSIIFIFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPPTYDTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEINGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNFSFKPCKETQIPLKLRFGGLLLTEKPIVLKAESRDETVSGA", "length": 503 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050604-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050604-1#orthology", "database": "AGR" }, { "id": "RGD:1595919", "url": "https://alliancegenome.org/gene/RGD:1595919#orthology", "database": "AGR" }, { "id": "RGD:708392", "url": "https://alliancegenome.org/gene/RGD:708392#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P51538-1", "protein_name": "Cytochrome P450 3A9", "gene_name": "Cyp3a9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLIPNFSMETWLLLVISLVLLYLYGTHSHGIFKKLGIPGPKPLPFLGTILAYRKGFWEFDKYCHKKYGKLWGLYDGRQPVLAITDPDIIKTVLVKECYSTFTNRRNFGPVGILKKAISISEDEEWKRIRALLSPTFTSGKLKEMFPIINQYTDMLVRNMRQGSEEGKPTSMKDIFGAYSMDVITATSFGVNVDSLNNPQDPFVEKVKKLLKFDIFDPLFLSVTLFPFLTPLFEALNVSMFPRDVIDFFKTSVERMKENRMKEKEKQRMDFLQLMINSQNSKVKDSHKALSDVEIVAQSVIFIFAGYETTSSALSFVLYLLAIHPDIQKKLQDEIDAALPNKAHATYDTLLQMEYLDMVVNETLRLYPIAGRLERVCKTDVEINGVFIPKGTVVMIPTFALHKDPHYWPEPEEFRPERFSKKNQDNINPYMYLPFGNGPRNCIGMRFALMNMKVALFRVLQNFSFQPCKETQIPLKLSKQGLLQPEKPLLLKVVSRDETVNGA", "length": 503 }, "evidence": [ { "id": "FB:FBgn0031726", "url": "https://alliancegenome.org/gene/FB:FBgn0031726#orthology", "database": "AGR" }, { "id": "HGNC:2638", "url": "https://alliancegenome.org/gene/HGNC:2638#orthology", "database": "AGR" }, { "id": "HGNC:2637", "url": "https://alliancegenome.org/gene/HGNC:2637#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050604-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050604-1#orthology", "database": "AGR" }, { "id": "RGD:708392", "url": "https://alliancegenome.org/gene/RGD:708392#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P54781-1", "protein_name": "C-22 sterol desaturase ERG5", "gene_name": "ERG5", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSSVAENIIQHATHNSTLHQLAKDQPSVGVTTAFSILDTLKSMSYLKIFATLICILLVWDQVAYQIKKGSIAGPKFKFWPIIGPFLESLDPKFEEYKAKWASGPLSCVSIFHKFVVIASTRDLARKILQSSKFVKPCVVDVAVKILRPCNWVFLDGKAHTDYRKSLNGLFTKQALAQYLPSLEQIMDKYMDKFVRLSKENNYEPQVFFHEMREILCALSLNSFCGNYITEDQVRKIADDYYLVTAALELVNFPIIIPYTKTWYGKKTADMAMKIFENCAQMAKDHIAAGGKPVCVMDAWCKLMHDAKNSNDDDSRIYHREFTNKEISEAVFTFLFASQDASSSLACWLFQIVADRPDVLAKIREEQLAVRNNDMSTELNLDLIEKMKYTNMVIKETLRYRPPVLMVPYVVKKNFPVSPNYTAPKGAMLIPTLYPALHDPEVYENPDEFIPERWVEGSKASEAKKNWLVFGCGPHVCLGQTYVMITFAALLGKFALYTDFHHTVTPLSEKIKVFATIFPKDDLLLTFKKRDPITGEVFE", "length": 538 }, "evidence": [ { "id": "RGD:628709", "url": "https://alliancegenome.org/gene/RGD:628709#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P82711-1", "protein_name": "Probable cytochrome P450 6a19", "gene_name": "Cyp6a19", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAILLGLVVGVLTLVAWWVLQNYTYWKRRGIPHDPPNIPLGNTGELWRTMPLAGILKRTYLKFRKQTDGPFAGFYLYAMKYIVITDVDFVKTVLIRDFDKFHDRGVYHNEKDDPLTNNLATIEGQKWKNLRQKLTHTFTSAKMKSMFSTVLNVGDEMIRVVDEKISSSSQTLEVTDIVSRFTSDVIGICAFGLKCNSLRDPKAEFVQMGYSALRERRHGWLVDLLIFGMPKLAVKLGFQFLLPSVQKFYMKIVQDTIDYRMKRKVTRNDFMDTLIDMKQQYDKGDKENGLAFNEVAAQAFVFFLAGFEAGSTTMGFTLYELACNQDVQDKLRAEIDSVLERYNGKLEYDSMQDLFYMEKVINESLRKHPVVAHLARIATKPYQHSNPKYFIEAGTGVLVSTLGIHHDPEFYPEPEKFIPERFDEEQVKKRPTCAFLPFGAGPRNCIGLRFGRMQVIIGLALLIHNFRFELHPKTPVPMKYTINNLLLGSEGGIHLNITKVVRD", "length": 503 }, "evidence": [ { "id": "RGD:628709", "url": "https://alliancegenome.org/gene/RGD:628709#orthology", "database": "AGR" }, { "id": "HGNC:2638", "url": "https://alliancegenome.org/gene/HGNC:2638#orthology", "database": "AGR" }, { "id": "HGNC:2637", "url": "https://alliancegenome.org/gene/HGNC:2637#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050604-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050604-1#orthology", "database": "AGR" }, { "id": "SGD:S000001049", "url": "https://alliancegenome.org/gene/SGD:S000001049#orthology", "database": "AGR" }, { "id": "RGD:1595919", "url": "https://alliancegenome.org/gene/RGD:1595919#orthology", "database": "AGR" }, { "id": "RGD:708379", "url": "https://alliancegenome.org/gene/RGD:708379#orthology", "database": "AGR" }, { "id": "RGD:708392", "url": "https://alliancegenome.org/gene/RGD:708392#orthology", "database": "AGR" }, { "id": "RGD:628626", "url": "https://alliancegenome.org/gene/RGD:628626#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q16850-1", "protein_name": "Lanosterol 14-alpha demethylase", "gene_name": "CYP51A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAAGMLLLGLLQAGGSVLGQAMEKVTGGNLLSMLLIACAFTLSLVYLIRLAAGHLVQLPAGVKSPPYIFSPIPFLGHAIAFGKSPIEFLENAYEKYGPVFSFTMVGKTFTYLLGSDAAALLFNSKNEDLNAEDVYSRLTTPVFGKGVAYDVPNPVFLEQKKMLKSGLNIAHFKQHVSIIEKETKEYFESWGESGEKNVFEALSELIILTASHCLHGKEIRSQLNEKVAQLYADLDGGFSHAAWLLPGWLPLPSFRRRDRAHREIKDIFYKAIQKRRQSQEKIDDILQTLLDATYKDGRPLTDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTLQKKCYLEQKTVCGENLPPLTYDQLKDLNLLDRCIKETLRLRPPIMIMMRMARTPQTVAGYTIPPGHQVCVSPTVNQRLKDSWVERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYEFDLIDGYFPTVNYTTMIHTPENPVIRYKRRSK", "length": 509 }, "evidence": [ { "id": "SGD:S000001049", "url": "https://alliancegenome.org/gene/SGD:S000001049#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q1JPY5-1", "protein_name": "Lanosterol 14-alpha demethylase", "gene_name": "cyp51", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTILEVGSQLIESAVLQMSLTSVLLTASVFTLTLGYFSKLLFTQHSSEHTKYPPHIPSSLPFLGQAVAFGRSPIEFLEKAYEQYGPVVSFTMVGKTFTYLLGSDAAALMFNSKNEDLNAEDVYARLTTPVFGKGVAYDVPNPLFLEQKKMLKTGLNIAQFKQHVEIIEEETKDYFRRWGESGERNLFDALSELIILTASRCLHGCEIRSLLDERVAQLYADLDGGFTHAAWLLPGWLPLPSFRRRDRAHLEIKKIFYNVIKKRREDTEKHDDILQTLIDATYKDGRPLSDDEIAGMLIGLLLAGQHTSSTTSAWMGFFLARDRALQERCYSEQKSVCGEELPPLHYDQLKDLSLLDRCLKETLRLRPPIMTMMRMAKTPQKVGEYTIPPGHQVCVSPTVNHRLQDTWAERLDFDPDRYLHDNPAAGEKFAYIPFGAGRHRCIGENFAYVQIKTIWSTLLRMFDFELVDGHFPPVNYTTMIHTPHNPIIRYTRRNTQPQQ", "length": 499 }, "evidence": [ { "id": "SGD:S000001049", "url": "https://alliancegenome.org/gene/SGD:S000001049#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q27593-1", "protein_name": "Cytochrome P450 6a8", "gene_name": "Cyp6a8", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MALTYILFQVAVALLAILTYYIHRKLTYFKRRGIPFVAPHLIRGNMEELQKTKNIHEIFQDHYNKFRESKAPFVGFFFFQSPAAFVIDLELAKQILIKDFSNFSNKGIFYNEKDDPISAHLFNLDGAQWRLLRNKLSSTFTSGKMKLMYPTVVSVANEFMTVMHEKVPKNSVLEIRDLVARFTVDVIGTCAFGIQCNSLRDEKAEFLYFGKRSLVDKRHGTLLNGFMRSYPKLARKLGMVRTAPHIQEFYSRIVTETVAVREKEHIKRNDFMDMLIELKNQKEMTLENGDVVRGLTMEEVLAQAFVFFIAGFETSSSTMGFALYELAKNPDIQDKVRAEVEEVIEQHDQNFTYECTKDLKYLNQVLDETLRLYTIVPNLDRMAAKRYVVPGHPNFVIEAGQSVIIPSSAIHHDPSIYPEPFEFRPERFSPEESAGRPSVAWLPFGDGPRNCIGLRFGQMQARIGLALLIRNFKFSTCSKTPNPLVYDPKSFVLGVKDGIYLKVETV", "length": 506 }, "evidence": [ { "id": "RGD:628709", "url": "https://alliancegenome.org/gene/RGD:628709#orthology", "database": "AGR" }, { "id": "HGNC:2638", "url": "https://alliancegenome.org/gene/HGNC:2638#orthology", "database": "AGR" }, { "id": "HGNC:2637", "url": "https://alliancegenome.org/gene/HGNC:2637#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050604-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050604-1#orthology", "database": "AGR" }, { "id": "SGD:S000001049", "url": "https://alliancegenome.org/gene/SGD:S000001049#orthology", "database": "AGR" }, { "id": "RGD:1595919", "url": "https://alliancegenome.org/gene/RGD:1595919#orthology", "database": "AGR" }, { "id": "RGD:708379", "url": "https://alliancegenome.org/gene/RGD:708379#orthology", "database": "AGR" }, { "id": "RGD:708392", "url": "https://alliancegenome.org/gene/RGD:708392#orthology", "database": "AGR" }, { "id": "RGD:628626", "url": "https://alliancegenome.org/gene/RGD:628626#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q27594-1", "protein_name": "Cytochrome P450 6a9", "gene_name": "Cyp6a9", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGVYSVLLAIVVVLVGYLLLKWRRALHYWQNLDIPCEEPHILMGSLTGVQTSRSFSAIWMDYYNKFRGTGPFAGFYWFQRPGILVLDISLAKLILIKEFNKFTDRGFYHNTEDDPLSGQLFLLDGQKWKSMRSKLSYTFTSGKMKYMFPTVVKVGHEFIEVFGQAMEKSPIVEVRDILARFTTDVIGTCAFGIECSSLKDPEAEFRVMGRRAIFEQRHGPIGIAFINSFQNLARRLHMKITLEEAEHFFLRIVRETVAFREKNNIRRNDFMDQLIDLKNSPLTKSESGESVNLTIEEMAAQAFVFFGAGFETSSTTMGFALYELAQHQDIQDRVRKECQEVIGKYNGEITYESMKDMVYLDQVISETLRLYTVLPVLNRECLEDYEVPGHPKYVIKKGMPVLIPCGAMHRDEKLYANPNTFNPDNFSPERVKERDSVEWLPFGDGPRNCIGMRFGQMQARSGLALLINRFKFSVCEQTTIPIVYSKKTFLISSETGIFLKVERV", "length": 504 }, "evidence": [ { "id": "RGD:628709", "url": "https://alliancegenome.org/gene/RGD:628709#orthology", "database": "AGR" }, { "id": "HGNC:2638", "url": "https://alliancegenome.org/gene/HGNC:2638#orthology", "database": "AGR" }, { "id": "HGNC:2637", "url": "https://alliancegenome.org/gene/HGNC:2637#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050604-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050604-1#orthology", "database": "AGR" }, { "id": "SGD:S000001049", "url": "https://alliancegenome.org/gene/SGD:S000001049#orthology", "database": "AGR" }, { "id": "RGD:1595919", "url": "https://alliancegenome.org/gene/RGD:1595919#orthology", "database": "AGR" }, { "id": "RGD:708379", "url": "https://alliancegenome.org/gene/RGD:708379#orthology", "database": "AGR" }, { "id": "RGD:708392", "url": "https://alliancegenome.org/gene/RGD:708392#orthology", "database": "AGR" }, { "id": "RGD:628626", "url": "https://alliancegenome.org/gene/RGD:628626#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q64459-1", "protein_name": "Cytochrome P450 3A11", "gene_name": "Cyp3a11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLVSALSLETWVLLAISLVLLYRYGTRKHELFKKQGIPGPKPLPFLGTVLNYYKGLWKFDMECYKKYGKTWGLFDGQTPLLAVTDPETIKNVLVKECFSVFTNRRDFGPVGIMSKAISISKDDEWKRYRALLSPTFTSGKLKEMFPVIEQYGDILVKYLRQKAKKGKPVTMKDVLGAYSMDVITSTSFGVNVDSLNNPEDPFVEKAKKLLRFDFFDPLLFSVVLFPFLTPVYEMLNICMFPKDSIEFFKKFVDRMKESRLDSKQKHRVDFLQLMMNSHNNSKDKVSHKALSDMEITAQSIIFIFAGYETTSSTLSFTLHSLATHPDIQKKLQDEIDEALPNKAPPTYDTVMEMEYLDMVLNETLRLYPIANRLERVCKKDVELNGVYIPKGSTVMIPSYALHHDPQHWSEPEEFQPERFSKENKGSIDPYVYLPFGNGPRNCLGMRFALMNMKLALTKIMQNFSFQPCKETQIPLKLSRQGLLQPEKPIVLKVVPRDAVITGA", "length": 504 }, "evidence": [ { "id": "HGNC:2638", "url": "https://alliancegenome.org/gene/HGNC:2638#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050604-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050604-1#orthology", "database": "AGR" }, { "id": "RGD:708379", "url": "https://alliancegenome.org/gene/RGD:708379#orthology", "database": "AGR" }, { "id": "RGD:628626", "url": "https://alliancegenome.org/gene/RGD:628626#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q64464-1", "protein_name": "Cytochrome P450 3A13", "gene_name": "Cyp3a13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLIPNFSMETWMLLATSLVLLYLYGTHSHGIFKKLGIPGPKPLPFLGTILAYQKGFWECDIQCHKKYGKMWGLYDGRQPVLAITDPDIIKTVLVKECYSTFTNRRRFGPVGILKKAISISENEEWKRIRALLSPTFTSGRLKEMFPIINQFTDVLVRNMRQGLGEGKPTSMKDIFGAYSMDVITATSFGVNIDSLNNPQDPFVEKIKKLLKFDIFDPLFLSVTLFPFLTPVFDALNVSLFPRDVISFFTTSVERMKENRMKEKEKQRVDFLQLMINSQNYKTKESHKALSDVEIVAQSVIFIFAGYETTSSALSFALYLLAIHPDVQKKLQDEIDAALPNKAPATYDTLLQMEYLDMVVNETLRLYPIAGRLERVCKTDVEINGLFIPKGTVVMIPTFALHKDPKYWPEPEEFRPERFSKKNQDSINPYMYLPFGSGPRNCIGMRFALINMKVALVRVLQNFTVQPCKETEIPLKLSKQGLLQPENPLLLKVVSRDETVSDE", "length": 503 }, "evidence": [ { "id": "HGNC:2638", "url": "https://alliancegenome.org/gene/HGNC:2638#orthology", "database": "AGR" }, { "id": "HGNC:2637", "url": "https://alliancegenome.org/gene/HGNC:2637#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050604-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050604-1#orthology", "database": "AGR" }, { "id": "RGD:708392", "url": "https://alliancegenome.org/gene/RGD:708392#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q64481-1", "protein_name": "Cytochrome P450 3A16", "gene_name": "Cyp3a16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNLFSALSLDTLVLLAIILVLLYRYGTCTHGLFKKQGIPGPKPLPFLGTVLNYYKGLWKFDMECYEKYGKTWGLFDGQIPLFVITDPETIKNVLVKECFSVFTNRQDFFPVGIMSKSISLAKDEEWKRYRALLSPTFTSGNLKEMFPVIEQYGDILVKYLRQEAEKGKPVAVKDVLGAYSMDVIISTTFGVNIDSLNNPEDPFVENAKKVLRFDYFDPLSLSVALFPFLTPIYEMLNICMFPKDSIEFFKKFVDRMTENRLDSKQKHRVDFIYLMMEAYNKSKDKDSHKALSEIEITAQSIIFIFAGYETTSSILSFTVYSLATHPDIQKKLQEEIDEALPNKAPPTYDTVMAMEYLDMVLNETLRLYPITNRLQRVCKKDVEINGIYIPKGSTVIIPSYVLHHDPQHWPEPEEFQPERFSKENKGSIDPYVYLPFGNGPRNCIGMRFALMNMKLALIKVLQNFSFQPCKETQIPLKLSRELLLQPVKPIVLKVVPRDAVITGA", "length": 504 }, "evidence": [ { "id": "HGNC:2638", "url": "https://alliancegenome.org/gene/HGNC:2638#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050604-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050604-1#orthology", "database": "AGR" }, { "id": "RGD:708379", "url": "https://alliancegenome.org/gene/RGD:708379#orthology", "database": "AGR" }, { "id": "RGD:628626", "url": "https://alliancegenome.org/gene/RGD:628626#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q64581-1", "protein_name": "Cytochrome P450 3A18", "gene_name": "Cyp3a18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEIIPNLSIETWVLLATSLMLFYIYGTYSHGLFKKLGIPGPKPVPLFGTIFNYGDGMWKFDDDCYKKYGKIWGFYEGPQPFLAIMDPEIIKMVLVKECYSVFTNRRCFGPMGFMKKAITMSEDEEWKRLRTILSPTFTSGKLKEMFPLMRQYGDTLLKNLRREEAKGEPINMKDIFGAYSMDVITGTSFGVNVDSLNNPQDPFVQKAKKILKFQIFDPFLLSVVLFPFLTPIYEMLNFSIFPRQSMNFFKKFVKTMKKNRLDSNQKNRVDFLQLMMNTQNSKGQESQKALSDLEMAAQAIIFIFGGYDATSTSISFIMYELATRPNVQKKLQNEIDRALPNKAPVTYDALMEMEYLDMVVNESLRLYPIATRLDRVSKKDVEINGVFIPKGTVVTIPIYPLHRNPEYWLEPEEFNPERFSKENKGSIDPYVYLPFGNGPRNCIGMRFALISMKLAVIGVLQNFNIQPCEKTQIPLKISRQPIFQPEGPIILKLVSRD", "length": 497 }, "evidence": [ { "id": "FB:FBgn0031726", "url": "https://alliancegenome.org/gene/FB:FBgn0031726#orthology", "database": "AGR" }, { "id": "RGD:628709", "url": "https://alliancegenome.org/gene/RGD:628709#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050604-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050604-1#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q64654-1", "protein_name": "Lanosterol 14-alpha demethylase", "gene_name": "Cyp51a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVLLGLLQSGGSVLGQAMEQVTGGNLLSTLLIACAFTLSLVYLFRLAVGHMVQLPAGAKSPPYIYSPIPFLGHAIAFGKSPIEFLENAYEKYGPVFSFTMVGKTFTYLLGSDAAALLFNSKNEDLNAEEVYGRLTTPVFGKGVAYDVPNAVFLEQKKILKSGLNIAHFKQYVSIIEKEAKEYFKSWGESGERNVFEALSELIILTASHCLHGKEIRSQLNEKVAQLYADLDGGFSHAAWLLPGWLPLPSFRRRDRAHREIKNIFYKAIQKRRLSKEPAEDILQTLLDSTYKDGRPLTDDEIAGMLIGLLLAGQHTSSTTSAWMGFFLARDKPLQDKCYLEQKTVCGEDLPPLTYEQLKDLNLLDRCIKETLRLRPPIMTMMRMAKTPQTVAGYTIPPGHQVCVSPTVNQRLKDSWVERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYEFDLINGYFPSVNYTTMIHTPENPVIRYKRRSK", "length": 503 }, "evidence": [ { "id": "SGD:S000001049", "url": "https://alliancegenome.org/gene/SGD:S000001049#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8K0C4-1", "protein_name": "Lanosterol 14-alpha demethylase", "gene_name": "Cyp51a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLLGLLQSGGWVLGQAMEQVTGGNLLSTLLIACAFTLSLVYLFRLAVGHMVQLPAGAKSPPHIYSPIPFLGHAIAFGKSPIEFLENAYEKYGPVFSFTMVGKTFTYLLGSDAAALLFNSKNEDLNAEEVYGRLTTPVFGKGVAYDVPNAIFLEQKKIIKSGLNIAHFKQYVPIIEKEAKEYFQSWGESGERNVFEALSELIILTASHCLHGKEIRSQLNEKVAQLYADLDGGFTHAAWLLPAWLPLPSFRRRDRAHREIKNIFYKAIQKRRLSKEPAEDILQTLLDSTYKDGRPLTDEEISGMLIGLLLAGQHTSSTTSAWMGFFLAKDKPLQEKCYLEQKAVCGEDLPPLTYDQLKDLNLLDRCIKETLRLRPPIMTMMRMAKTPQTVAGYTIPPGHQVCVSPTVNQRLKDSWAERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCVGENFAYVQIKTIWSTMLRLYEFDLINGYFPTVNYTTMIHTPENPVIRYKRRSK", "length": 503 }, "evidence": [ { "id": "SGD:S000001049", "url": "https://alliancegenome.org/gene/SGD:S000001049#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9HB55-1", "protein_name": "Cytochrome P450 3A43", "gene_name": "CYP3A43", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDLIPNFAMETWVLVATSLVLLYIYGTHSHKLFKKLGIPGPTPLPFLGTILFYLRGLWNFDRECNEKYGEMWGLYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEWKRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVNLDSLNNPQDPFLKNMKKLLKLDFLDPFLLLISLFPFLTPVFEALNIGLFPKDVTHFLKNSIERMKESRLKDKQKHRVDFFQQMIDSQNSKETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKPCKETQIPLKLDNLPILQPEKPIVLKVHLRDGITSGP", "length": 503 }, "evidence": [ { "id": "RGD:628709", "url": "https://alliancegenome.org/gene/RGD:628709#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050604-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050604-1#orthology", "database": "AGR" }, { "id": "RGD:708379", "url": "https://alliancegenome.org/gene/RGD:708379#orthology", "database": "AGR" }, { "id": "RGD:708392", "url": "https://alliancegenome.org/gene/RGD:708392#orthology", "database": "AGR" }, { "id": "RGD:628626", "url": "https://alliancegenome.org/gene/RGD:628626#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JMA7-1", "protein_name": "Cytochrome P450 3A41", "gene_name": "Cyp3a41a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNLFSALSLDTWVLLAIILVLLYRYGTRTHGLFKKQGIPGPKPLPFLGTVLNYYKGLWKFDMECYEKYGKTWGLFDGQMPLFVITDPEMIKNVLVKECFSVFTNRREFGPVGIMSKAISISKDEEWKRYRALLSPTFTSGKLKEMFPVIEQYGDILVKYLMQEAEKGKPVTMKDVLGAYSIDVITSTSFGVNVDSLNNPEDPFVEKAKGILRVDFFDPLVFSVVLFPFLTPVYEMLNICMFPKDSIEFFKKFVNRMKESRLDSKQKHRVDFLQLMMNAHNNSKDKDSHKALSDMEITAQSIVFIFAGYETTSSTLSFTLYCLATHPDIQKKLQEEIDETLPNKAPPTYDTVMEMEYLDMVLNETLRLYPIGNRLERFCKKDVELNGVYIPKGSTVMIPSYALHHDPQHWPEPEEFQPERFSKENKGSIDPYLYMPFGIGPRNCIGMRFAFMTMKLALTKVMQNFSFQPCQETQIPLKLSRQGLLQPEKPIVLKVVPRDVVITGA", "length": 504 }, "evidence": [ { "id": "HGNC:2638", "url": "https://alliancegenome.org/gene/HGNC:2638#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050604-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050604-1#orthology", "database": "AGR" }, { "id": "RGD:708379", "url": "https://alliancegenome.org/gene/RGD:708379#orthology", "database": "AGR" }, { "id": "RGD:628626", "url": "https://alliancegenome.org/gene/RGD:628626#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9LXX7-1", "protein_name": "Cytochrome P450, family 94, subfamily D, polypeptide 2", "gene_name": "CYP94D2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEHFILISLLCFPIVIFFIFFPKNSSSEFGFKSYPIVGSLPGLVNNRHRFLDWTVETLSRCPTQTAIFRRPGKLQFVMTANPANVEYMLKTKFESFPKGERFISILEDFLGRGIFNSDGEMWWKQRKTASYEFSTKSLRDFVMSNVTVEINTRLVPVLAEAATNGKLIDLQDILERFAFDNICKLAFNVDSACLGDDGAAGVNFMQAFETAATIISQRFQSVISYSWKIKKKLNIGSERVLRESIMIVHKFADEIVRNRIEQGKVSDHKEDLLSRFISKEEMNSPEILRDIVISFILAGRDTTSSALSWFFWLLSMHPEVKDKILQELNSIRERTGKRIGEVYGFEDLKLMNYLHAAITESLRLYPPVPVDTMSCAEDNVLPDGTFIGKDWGISYNAYAMGRMESIWGKDCDRFDPERWIDETNGGFRGENPYKFPAFHAGPRMCLGKEMAYIQMKSIVAAVLERFVVEVPGKKERPEILMSVTLRIRGGLNVRVQERS", "length": 499 }, "evidence": [ { "id": "X2J9F6", "url": "https://omabrowser.org/oma/group/X2J9F6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9V4I0-1", "protein_name": "Cytochrome P450 9b1", "gene_name": "Cyp9b1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSFVEICLVLATIGLLLFKWSTGTFKAFEGRNLYFEKPYPFLGNMAASALQKASFQKQISEFYNRTRHHKLVGLFNLRTPMIQINDPQLIKKICVKDFDHFPNHQTLNIPNERLVNDMLNVMRDQHWRNMRSVLTPVFTSAKMRNMFTLMNESFAQCLEHLKSSQPIAAGENAFELDMKVLCNKLSNDVIATTAFGLKVNSFDDPENEFHTIGKTLAFSRGLPFLKFMMCLLAPKVFNFFKLTIFDSTNVEYFVRLVVDAMQYREKHNITRPDMIQLLMEAKKESKDNWTDDEIVAQCFIFFFAAFENNSNLICTTAYELLRNLDIQERLYEEVKETQEALKGAPLTYDAAQEMTYMDMVISESLRKWTLSAAADRLCAKDYTLTDDEGTKLFEFKAGDNINIPICGLHWDERFFPQPQRFDPERFSERRKKDLIPYTYLPFGVGPRSCIGNRYAVMQAKGMLYNLMLNYKIEASPRTTRDMWESARGFNIIPTTGFWMQLVSRK", "length": 505 }, "evidence": [ { "id": "RGD:628709", "url": "https://alliancegenome.org/gene/RGD:628709#orthology", "database": "AGR" }, { "id": "HGNC:2638", "url": "https://alliancegenome.org/gene/HGNC:2638#orthology", "database": "AGR" }, { "id": "HGNC:2637", "url": "https://alliancegenome.org/gene/HGNC:2637#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050604-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050604-1#orthology", "database": "AGR" }, { "id": "SGD:S000001049", "url": "https://alliancegenome.org/gene/SGD:S000001049#orthology", "database": "AGR" }, { "id": "RGD:1595919", "url": "https://alliancegenome.org/gene/RGD:1595919#orthology", "database": "AGR" }, { "id": "RGD:708379", "url": "https://alliancegenome.org/gene/RGD:708379#orthology", "database": "AGR" }, { "id": "RGD:708392", "url": "https://alliancegenome.org/gene/RGD:708392#orthology", "database": "AGR" }, { "id": "RGD:628626", "url": "https://alliancegenome.org/gene/RGD:628626#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9V4I1-1", "protein_name": "Cytochrome P450 9b2", "gene_name": "Cyp9b2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MALIEICLALVVIGYLIYKWSTATFKTFEERKLYFEKPYPFVGNMAAAALQKSSFQRQLTEFYERTRQHKLVGFFNMRTPMITLNDPELIKKVCVKDFDHFPNHQPFITSNDRLFNDMLSVMRDQRWKHMRNTLTPVFTAAKMRNMFTLMNESFAECLQHLDSSSKTLPGRKGFEVDMKVMCNKLSNDIIATTAFGLKVNSYDNPKNEFYEIGQSLVFSRGLQFFKFMLSTLVPKLFSLLKLTIFDSAKVDYFARLVVEAMQYREKHNITRPDMIQLLMEAKNESEDKWTDDEIVAQCFIFFFAAFENNSNLICTTTYELLYNPDVQERLYEEIVETKKALNGAPLTYDAVQKMTYMDMVISESLRKWTLAAATDRLCSKDYTLTDDDGTKLFDFKVGDRINIPISGLHLDDRYFPEPRKFDPDRFSEERKGDMVPYTYLPFGVGPRNCIGNRYALMQVKGMLFNLLLHYKIEASPRTIKDLWGSASGFNFTPRSGFWMHLVPRK", "length": 505 }, "evidence": [ { "id": "RGD:628709", "url": "https://alliancegenome.org/gene/RGD:628709#orthology", "database": "AGR" }, { "id": "HGNC:2638", "url": "https://alliancegenome.org/gene/HGNC:2638#orthology", "database": "AGR" }, { "id": "HGNC:2637", "url": "https://alliancegenome.org/gene/HGNC:2637#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050604-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050604-1#orthology", "database": "AGR" }, { "id": "SGD:S000001049", "url": "https://alliancegenome.org/gene/SGD:S000001049#orthology", "database": "AGR" }, { "id": "RGD:1595919", "url": "https://alliancegenome.org/gene/RGD:1595919#orthology", "database": "AGR" }, { "id": "RGD:708379", "url": "https://alliancegenome.org/gene/RGD:708379#orthology", "database": "AGR" }, { "id": "RGD:708392", "url": "https://alliancegenome.org/gene/RGD:708392#orthology", "database": "AGR" }, { "id": "RGD:628626", "url": "https://alliancegenome.org/gene/RGD:628626#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9V4U7-1", "protein_name": "Probable cytochrome P450 6a14", "gene_name": "Cyp6a14", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLFTIALVGVVLGLAYSLHIKIFSYWKRKGVPHETPLPIVGNMRGIVKKYHFRDINQRIYKKFKGQGPIAGMYMFFKRTALITDLDFIKQVMIKDFSYFQDRGAFTNPRDDPLTGHLFALEGEEWRAMRHKLTPVFTSGKIKQMSKVIVDVGLRLGDAMDKAVKEAKVEEGNVEIKDLCARFTTDVIGSCAFGLECNSLQDPSAEFRQKGREIFTRRRHSTLVQSFIFTNARLARKLRIKVLPDDLTQFFMSTVKNTVDYRLKNGIKRNDFIEQMIELRAEDQEAAKKGQGIDLSHGLTLEQMAAQAFVFFVAGFETSSSTMSLCLYELALQPDIQQRLREEIESVLANVDGGELNYDVLAQMTYLDQVLSETLRKHPLLPHLIRETTKDYQIPNSDIVLDKGILALIPVHNIHHDPEIYPEPEKFDPSRFDPEEVKNRHPMAYLPFGDGPRNCIGLRFGKIQAKIGLVSLLRRFKFSVSNRTDVPLIFSKKSFLLTTNDGIYLKVERV", "length": 509 }, "evidence": [ { "id": "RGD:628709", "url": "https://alliancegenome.org/gene/RGD:628709#orthology", "database": "AGR" }, { "id": "HGNC:2638", "url": "https://alliancegenome.org/gene/HGNC:2638#orthology", "database": "AGR" }, { "id": "HGNC:2637", "url": "https://alliancegenome.org/gene/HGNC:2637#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050604-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050604-1#orthology", "database": "AGR" }, { "id": "SGD:S000001049", "url": "https://alliancegenome.org/gene/SGD:S000001049#orthology", "database": "AGR" }, { "id": "RGD:1595919", "url": "https://alliancegenome.org/gene/RGD:1595919#orthology", "database": "AGR" }, { "id": "RGD:708379", "url": "https://alliancegenome.org/gene/RGD:708379#orthology", "database": "AGR" }, { "id": "RGD:708392", "url": "https://alliancegenome.org/gene/RGD:708392#orthology", "database": "AGR" }, { "id": "RGD:628626", "url": "https://alliancegenome.org/gene/RGD:628626#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9V4U9-1", "protein_name": "Probable cytochrome P450 6a13", "gene_name": "Cyp6a13", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLTLLVLVFTVGLLLYVKLRWHYSYWSRRGVAGERPVYFRGNMSGLGRDLHWTDINLRIYRKFRGVERYCGYFTFMTKSLFIMDLELIRDIMIRDFSSFADRGLFHNVRDDPLTGNLLFLDGPEWRWLRQNLTQVFTSGKMKFMFPNMVEVGEKLTQACRLQVGEIEAKDLCARFTTDVIGSCAFGLECNSLQDPESQFRRMGRSVTQEPLHSVLVQAFMFAQPELARKLRFRLFRPEVSEFFLDTVRQTLDYRRRENIHRNDLIQLLMELGEEGVKDALSFEQIAAQALVFFLAGFDTSSTTMSFCLYELALNPDVQERLRVEVLAVLKRNNQKLTYDSVQEMPYLDQVVAETLRKYPILPHLLRRSTKEYQIPNSNLILEPGSKIIIPVHSIHHDPELYPDPEKFDPSRFEPEEIKARHPFAYLPFGEGPRNCIGERFGKLQVKVGLVYLLRDFKFSRSEKTQIPLKFSSRNFLISTQEGVHLRMEGLERP", "length": 493 }, "evidence": [ { "id": "RGD:628709", "url": "https://alliancegenome.org/gene/RGD:628709#orthology", "database": "AGR" }, { "id": "HGNC:2638", "url": "https://alliancegenome.org/gene/HGNC:2638#orthology", "database": "AGR" }, { "id": "HGNC:2637", "url": "https://alliancegenome.org/gene/HGNC:2637#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050604-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050604-1#orthology", "database": "AGR" }, { "id": "SGD:S000001049", "url": "https://alliancegenome.org/gene/SGD:S000001049#orthology", "database": "AGR" }, { "id": "RGD:1595919", "url": "https://alliancegenome.org/gene/RGD:1595919#orthology", "database": "AGR" }, { "id": "RGD:708392", "url": "https://alliancegenome.org/gene/RGD:708392#orthology", "database": "AGR" }, { "id": "RGD:628626", "url": "https://alliancegenome.org/gene/RGD:628626#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9V674-1", "protein_name": "Cytochrome P450 6g1", "gene_name": "Cyp6g1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVLTEVLFVVVAALVALYTWFQRNHSYWQRKGIPYIPPTPIIGNTKVVFKMENSFGMHLSEIYNDPRLKDEAVVGIYSMNKPGLIIRDIELIKSILIKDFNRFHNRYARCDPHGDPLGYNNLFFVRDAHWKGIRTKLTPVFTSGKVKQMYTLMQEIGKDLELALQRRGEKNSGSFITEIKEICAQFSTDSIATIAFGIRANSLENPNAEFRNYGRKMFTFTVARAKDFFVAFFLPKLVSLMRIQFFTADFSHFMRSTIGHVMEERERSGLLRNDLIDVLVSLRKEAAAEPSKPHYAKNQDFLVAQAGVFFTAGFETSSSTMSFALYEMAKHPEMQKRLRDEINEALVEGGGSLSYEKIQSLEYLAMVVDEVLRMYPVLPFLDREYESVEGQPDLSLKPFYDYTLENGTPVFIPIYALHHDPKYWTNPSQFDPERFSPANRKNIVAMAYQPFGSGPHNCIGSRIGLLQSKLGLVSLLKNHSVRNCEATMKDMKFDPKGFVLQADGGIHLEIVNDRLYDQSAPSLQ", "length": 524 }, "evidence": [ { "id": "RGD:628709", "url": "https://alliancegenome.org/gene/RGD:628709#orthology", "database": "AGR" }, { "id": "HGNC:2638", "url": "https://alliancegenome.org/gene/HGNC:2638#orthology", "database": "AGR" }, { "id": "HGNC:2637", "url": "https://alliancegenome.org/gene/HGNC:2637#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050604-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050604-1#orthology", "database": "AGR" }, { "id": "SGD:S000001049", "url": "https://alliancegenome.org/gene/SGD:S000001049#orthology", "database": "AGR" }, { "id": "RGD:1595919", "url": "https://alliancegenome.org/gene/RGD:1595919#orthology", "database": "AGR" }, { "id": "RGD:708379", "url": "https://alliancegenome.org/gene/RGD:708379#orthology", "database": "AGR" }, { "id": "RGD:708392", "url": "https://alliancegenome.org/gene/RGD:708392#orthology", "database": "AGR" }, { "id": "RGD:628626", "url": "https://alliancegenome.org/gene/RGD:628626#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9V675-1", "protein_name": "Probable cytochrome P450 6g2", "gene_name": "Cyp6g2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MELVLLILVASLIGIAFLALQQHYSYWRRMGVREIRPKWIVGNLMGLLNMRMSPAEFISQLYNHPDAENEPFVGIHVFHKPALLLRDPEMVRNILVKDFAGFSNRYSSSDPKGDPLGSQNIFFLKNPAWKEVRLKLSPFFTGNRLKQMFPLIEEVGASLDAHLRQQPLHNERMRCFDLEAKELCALYTTDVIATVAYGVSANSFTDPKCEFRRHGRSVFEFNLLRAAEFTLVFFLPHLVPFVRFKVVPAEATRFLRKTINYVMSEREKSGQKRNDLIDILIEFRRSTQLAKASGIKDQFVFEGDILVAQAVLFFTAGFESSSSTMAFAMYELAKDTDVQQRLREEIKDALVESGGQVTLKMIESLEFMQMILLEVLRMYPPLPFLDRECTSGRDYSLAPFHKKFVVPKGMPVYIPCYALHMDPQYFPQPRKFLPERFSPENRKLHTPYTYMPFGLGPHGCIGERFGYLQAKVGLVNLLRNHMITTSERTPHRMQLDPKAIITQAKGGIHLRLVRDALGV", "length": 519 }, "evidence": [ { "id": "RGD:628709", "url": "https://alliancegenome.org/gene/RGD:628709#orthology", "database": "AGR" }, { "id": "HGNC:2638", "url": "https://alliancegenome.org/gene/HGNC:2638#orthology", "database": "AGR" }, { "id": "HGNC:2637", "url": "https://alliancegenome.org/gene/HGNC:2637#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050604-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050604-1#orthology", "database": "AGR" }, { "id": "SGD:S000001049", "url": "https://alliancegenome.org/gene/SGD:S000001049#orthology", "database": "AGR" }, { "id": "RGD:1595919", "url": "https://alliancegenome.org/gene/RGD:1595919#orthology", "database": "AGR" }, { "id": "RGD:708392", "url": "https://alliancegenome.org/gene/RGD:708392#orthology", "database": "AGR" }, { "id": "RGD:628626", "url": "https://alliancegenome.org/gene/RGD:628626#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9V6H1-1", "protein_name": "Probable cytochrome P450 9h1", "gene_name": "Cyp9h1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDQSMIALALFIILLVLLYKWSVAKYDVFSERGVSHEKPWPLIGNIPLKAMIGGMPVLKKMIELHTKHTGSPVYGIYALRDAVFFVRDPELIKLIGIKEFDHFVNHNSMHNNIQESILSKSLISLRDGRWKEMRNILTPAFTGSKMRIMYDLIQSCSEEGVIHIQEQLELSQDASIELEMKDYFTRFANDVIATVAFGISINSFRRKDNEFFRIGQAMSRISAWSVVKAMLYALFPRLMKVLRIQVLDTKNIDYFSSLVTAAMRYRQEHKVVRPDMIHLLMEAKQQRLADLSDKSKDELYYSEFTADDLLAQCLLFFFAGFEIISSSLCFLTHELCLNPTVQDRLYEEIISVHEELKGQPLTYDKLTKMKYLDMVVLEALRKWPPSISTDRECRQDIDLFDENGQKLFSARKGDVLQIPIFSLHHDPENFEDPEFFNPERFADGHALESRVYMPFGVGPRNCIGNRMALMELKSIVYQLLLNFKLLPAKRTSRDLLNDIRGHGLKPKNGFWLKFEARQ", "length": 518 }, "evidence": [ { "id": "RGD:628709", "url": "https://alliancegenome.org/gene/RGD:628709#orthology", "database": "AGR" }, { "id": "HGNC:2638", "url": "https://alliancegenome.org/gene/HGNC:2638#orthology", "database": "AGR" }, { "id": "HGNC:2637", "url": "https://alliancegenome.org/gene/HGNC:2637#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050604-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050604-1#orthology", "database": "AGR" }, { "id": "RGD:1595919", "url": "https://alliancegenome.org/gene/RGD:1595919#orthology", "database": "AGR" }, { "id": "RGD:708379", "url": "https://alliancegenome.org/gene/RGD:708379#orthology", "database": "AGR" }, { "id": "RGD:708392", "url": "https://alliancegenome.org/gene/RGD:708392#orthology", "database": "AGR" }, { "id": "RGD:628626", "url": "https://alliancegenome.org/gene/RGD:628626#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9V769-1", "protein_name": "Cytochrome P450 6a22", "gene_name": "Cyp6a22", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLDVVALLLIALAVGFWFVRTRYSYWTRRGIGSEPARFPVGNMEGFRKNKHFIDIVTPIYEKFKGNGAPFAGFFMMLRPVVLVTDLELAKQILIQDFANFEDRGMYHNERDDPLTGHLFRIDGPKWRPLRQKMSPTFTSAKMKYMFPTVCEVGEELTQVCGELADNAMCGILEIGDLMARYTSDVIGRCAFGVECNGLRNPEAEFAIMGRRAFSERRHCKLVDGFIESFPEVARFLRMRQIHQDITDFYVGIVRETVKQREEQGIVRSDFMNLLIEMKQRGELTIEEMAAQAFIFFAAGFDTSASTLGFALYELAKQPALQAKLREEIDQALRLHNGEFTYDSMQELRYMELVIAETLRKYPILPQLTRISRHLYAAKGDRHFYIEPGQMLLIPVYGIHHDPALYPEPHKFIPERFLADQLAQRPTAAWLPFGDGPRNCIGMRFGKMQTTIGLVSLLRNFHFSVCPRTDPKIEFLKSNILLCPANGIYLKVQQLSQMSS", "length": 499 }, "evidence": [ { "id": "RGD:628709", "url": "https://alliancegenome.org/gene/RGD:628709#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050604-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050604-1#orthology", "database": "AGR" }, { "id": "SGD:S000001049", "url": "https://alliancegenome.org/gene/SGD:S000001049#orthology", "database": "AGR" }, { "id": "RGD:1595919", "url": "https://alliancegenome.org/gene/RGD:1595919#orthology", "database": "AGR" }, { "id": "RGD:708379", "url": "https://alliancegenome.org/gene/RGD:708379#orthology", "database": "AGR" }, { "id": "RGD:708392", "url": "https://alliancegenome.org/gene/RGD:708392#orthology", "database": "AGR" }, { "id": "RGD:628626", "url": "https://alliancegenome.org/gene/RGD:628626#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9V770-1", "protein_name": "Probable cytochrome P450 6a17", "gene_name": "Cyp6a17", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLLLALIVVILSLLVFAARRRHGYWQRRGIPHDEVHPLFGNIKDWPNKRHIAEIFRDYYFKYKNSDYPFAGFFFFFTRTAVVTDMELLKRVLIKDFNHFENRGVFYNEIDDPLSATLFSIEGQKWRHLRHKLTPTFTSGKMKNMFPIVVKVGEEMDKVFRSKTAADRGQVLEVVDLVARYTADVIGNCAFGLNCNSLYDPKAEFVSIGKRAITEHRYGNMLDIFLFGFPKLSRRLRLKLNIQEAEDFYTKIVRETIDYRLRTKEKRNDFMDSLIEMYKNEQSGNSEDGLTFNELLAQAFIFFVAGFETSSTTMGFALYELARNQDVQDKLREEIGNVFGKHNKEFTYEGIKEMKYLEQVVMETLRKYPVLAHLTRMTDTDFSPEDPKYFIAKGTIVVIPALGIHYDPDIYPEPEIFKPERFTDEEIAARPSCTWLPFGEGPRNCIGLRFGMMQTCVGLAYLIRGYKFSVSPETQIPMKIVVKNILISAENGIHLKVEKLAK", "length": 501 }, "evidence": [ { "id": "RGD:628709", "url": "https://alliancegenome.org/gene/RGD:628709#orthology", "database": "AGR" }, { "id": "HGNC:2638", "url": "https://alliancegenome.org/gene/HGNC:2638#orthology", "database": "AGR" }, { "id": "HGNC:2637", "url": "https://alliancegenome.org/gene/HGNC:2637#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050604-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050604-1#orthology", "database": "AGR" }, { "id": "SGD:S000001049", "url": "https://alliancegenome.org/gene/SGD:S000001049#orthology", "database": "AGR" }, { "id": "RGD:1595919", "url": "https://alliancegenome.org/gene/RGD:1595919#orthology", "database": "AGR" }, { "id": "RGD:708379", "url": "https://alliancegenome.org/gene/RGD:708379#orthology", "database": "AGR" }, { "id": "RGD:708392", "url": "https://alliancegenome.org/gene/RGD:708392#orthology", "database": "AGR" }, { "id": "RGD:628626", "url": "https://alliancegenome.org/gene/RGD:628626#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9V771-1", "protein_name": "Probable cytochrome P450 6a23", "gene_name": "Cyp6a23", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSLLLTLIALLVSLLLFMARRRHGYWQRRGIPHDVPHPIYGNMKDWPKKRHIAMIFRDYYTKYKRSVYPFAGFYFFFTRSAVITDLELVKRVLIKDFNHFENRGIFYNEIDDPLSATLFSIEGQKWRHLRHKLTPTFTSGKMKNMFPIIVKVGEEMEKIFSAKTTTGEGQVLEIVDLVARYTADVIGNCAFGLNCNSLQNPNAEFVTIGKRAIIERRYGGLLDFLIFGFPKLSRRLRLKLNVQDVEDFYTSIVRNTIDYRLRTNEKRHDFMDSLIEMYEKEQAGNTEDGLSFNEILAQAFIFFVAGFETSSTTMGFALYELALDQDIQDQLRAEINNVLSKHNNEFTYEGIKEMKYLEQVVMETLRKYPVLAHLTRMTQTDFSPEDPKYFIAKGTTVVIPALGIHYDPEIYPEPEKFKPERFTDEAIAARPSCTWLPFGEGPRNCIGLRFGLMQACVGLAYLIRGYKFSVSTETQIPMKFVVKSILLSAENGIHLKVEKLSK", "length": 502 }, "evidence": [ { "id": "RGD:628709", "url": "https://alliancegenome.org/gene/RGD:628709#orthology", "database": "AGR" }, { "id": "HGNC:2638", "url": "https://alliancegenome.org/gene/HGNC:2638#orthology", "database": "AGR" }, { "id": "HGNC:2637", "url": "https://alliancegenome.org/gene/HGNC:2637#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050604-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050604-1#orthology", "database": "AGR" }, { "id": "SGD:S000001049", "url": "https://alliancegenome.org/gene/SGD:S000001049#orthology", "database": "AGR" }, { "id": "RGD:1595919", "url": "https://alliancegenome.org/gene/RGD:1595919#orthology", "database": "AGR" }, { "id": "RGD:708379", "url": "https://alliancegenome.org/gene/RGD:708379#orthology", "database": "AGR" }, { "id": "RGD:708392", "url": "https://alliancegenome.org/gene/RGD:708392#orthology", "database": "AGR" }, { "id": "RGD:628626", "url": "https://alliancegenome.org/gene/RGD:628626#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9V773-1", "protein_name": "Probable cytochrome P450 6a20", "gene_name": "Cyp6a20", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAVMIVLLIGVITFVAWYVHQHFNYWKRRGIPHDEPKIPYGNTSELMKTVHFADIFKRTYNKLRNKTDGPFVGFYMYFKRMVVVTDIDFAKTVLIREFDKFHDRGVFHNERDDPLSANLVNIDGQKWKTLRQKLTPTFTSGKMKTMFPTILTVGDELIRVFGETASADSDSMEITNVVARFTADVIGSCAFGLDCHSLSDPKAKFVQMGTTAITERRHGKSMDLLLFGAPELAAKLRMKATVQEVEDFYMNIIRDTVDYRVKNNVKRHDFVDMLIEMKLKFDNGDKENGLTFNEIAAQAFIFFLAGFETSSTTMGFALYELACHQDIQDKLRTEINTVLKQHNGKLDYDSMREMTYLEKVIDETMRKRPVVGHLIRVATQHYQHTNPKYNIEKGTGVIVPTLAIHHDPEFYPEPEKFIPERFDEDQVQQRPACTFLPFGDGPRNCIGLRFGRMQVIVGMALLIHNFKFEFHPTKTVVPLEYRTDDFLLSSKGGIHLKVTRV", "length": 501 }, "evidence": [ { "id": "RGD:628709", "url": "https://alliancegenome.org/gene/RGD:628709#orthology", "database": "AGR" }, { "id": "HGNC:2638", "url": "https://alliancegenome.org/gene/HGNC:2638#orthology", "database": "AGR" }, { "id": "HGNC:2637", "url": "https://alliancegenome.org/gene/HGNC:2637#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050604-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050604-1#orthology", "database": "AGR" }, { "id": "SGD:S000001049", "url": "https://alliancegenome.org/gene/SGD:S000001049#orthology", "database": "AGR" }, { "id": "RGD:1595919", "url": "https://alliancegenome.org/gene/RGD:1595919#orthology", "database": "AGR" }, { "id": "RGD:708379", "url": "https://alliancegenome.org/gene/RGD:708379#orthology", "database": "AGR" }, { "id": "RGD:708392", "url": "https://alliancegenome.org/gene/RGD:708392#orthology", "database": "AGR" }, { "id": "RGD:628626", "url": "https://alliancegenome.org/gene/RGD:628626#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9V774-1", "protein_name": "Probable cytochrome P450 6a21", "gene_name": "Cyp6a21", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSVGTVLLTALLALVGYLLMKWRSTMRHWQDLGIPCEEPHILMGSMKGVRTARSFNEIWTSYYNKFRGSGPFAGFYWFRRPAVFVLETSLAKQILIKEFNKFTDRGFFHNPEDDPLSGQLFLLDGQKWRTMRNKLSSTFTSGKMKYMFPTVVKVANEFTDVFGQNVAKSPVVEVRELLARFTTDVIGTCAFGIECSSLKDPDAEFREMGRRSLTEQRLGPVGIGFVNSFPNLARRLHMKMTAEPIERFFMRIVRETVAFREQNNIRRNDFMDQLIDLKNKPLMVSQSGESVNLTIEEIAAQAFVFFAAGFETSSTTMGFALYELAQNQDIQNRVRKECQEVIEKCNGELNYESMKDLVYLDQVVSETLRLYTVLPVLNRECLEDYEVPGHPKYVIKKGMPVLIPCGAMHRDEKLYANPNTFNPDNFSPERVKERDSVEWLPFGDGPRNCIGMRFGQMQARIGLALLIKDFKFSVCEKTTIPMTYNKEMFLIASNSGIYLKAERV", "length": 504 }, "evidence": [ { "id": "RGD:628709", "url": "https://alliancegenome.org/gene/RGD:628709#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050604-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050604-1#orthology", "database": "AGR" }, { "id": "SGD:S000001049", "url": "https://alliancegenome.org/gene/SGD:S000001049#orthology", "database": "AGR" }, { "id": "RGD:1595919", "url": "https://alliancegenome.org/gene/RGD:1595919#orthology", "database": "AGR" }, { "id": "RGD:708379", "url": "https://alliancegenome.org/gene/RGD:708379#orthology", "database": "AGR" }, { "id": "RGD:708392", "url": "https://alliancegenome.org/gene/RGD:708392#orthology", "database": "AGR" }, { "id": "RGD:628626", "url": "https://alliancegenome.org/gene/RGD:628626#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9V776-1", "protein_name": "Probable cytochrome P450 317a1", "gene_name": "Cyp317a1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MWIIFLIIGLLVLGLLVLLIIAARYQRDYWRYLDIPHERPKKLWPIIRQIMTQTLSTEAMKAEHYSAIYKKFKGSGPFCGFYALLQPRALILDRELIRQIMIKDFWNFNDRGLYCNQKSDPLSGDLYALRGESWKEMRQKLDPSLEGDRMSLLYDCLYEEAEQLLLTVNSTLMSQPHSTVHIQKIMRRYVLSSLAKCVFGLNAEQRKTYPLEDFEQMTELALNSHKHGYLMNLMMIRFPNFCRMLRMRRTPKQAEEYFIKLLTSIVEQRETSGKPQKDYLQLLIDVKALEFITHQYEADKELGAHLQNELAAHAVVFLKAGYEQTANTLSYVLYELALHPELQVRVREEVKKAIERHDGHITHEGIKSLSFMGQVINETLRMHPITPYILRRTLNDYAVPDHPKYILVKELFLIIPTHAIHHDPDIYPDPEEFKPDRWSGPRDSLQEQGTWFGFGVGARSCIGIQFAQLQLRLALALLLSEYEFSLNTRKPLINLEDGIALTLMPLGVIEPGNEERAV", "length": 518 }, "evidence": [ { "id": "SGD:S000001049", "url": "https://alliancegenome.org/gene/SGD:S000001049#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9V979-1", "protein_name": "Probable cytochrome P450 6u1", "gene_name": "Cyp6u1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDLMHRTLLTALGALSVVYALVKFSLGYWKRRGILHEKPKFLWGNIKGVVSGKRHAQDALQDIYTAYKGRAPFVGFYACLKPFILALDLKLVHQIIFTDAGHFTSRGLYSNPSGEPLSHNLLQLDGHKWRSLHAKSAEVFTPANMQKLLVRLSQISSRIQRDLGEKSLQTINISELVGAYNTDVMASMAFGLVGQDNVEFAKWTRNYWADFRMWQAYLALEFPLIARLLQYKSYAEPATAYFQKVALSQLQLHRRRDRQPLQTFLQLYSNAEKPLTDIEIAGQAFGFVLAGLGPLNATLAFCLYELARQPEVQDRTRLEINKALEEHGGQVTPECLRELRYTKQVLNETLRLHTPHPFLLRRATKEFEVPGSVFVIAKGNNVLIPTAAIHMDPGIYENPQRFYPERFEEQARRSRPAAAFLPFGDGLRGCIAARFAEQQLLVGLVALLRQHRYAPSAETSIPVEYDNRRLLLMPKSDIKLSVERVDKL", "length": 488 }, "evidence": [ { "id": "SGD:S000001049", "url": "https://alliancegenome.org/gene/SGD:S000001049#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9V9L1-1", "protein_name": "Probable cytochrome P450 6w1", "gene_name": "Cyp6w1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLLLLLLGSLTIVFYIWQRRTLSFWERHGVKYIRPFPVVGCTREFLTAKVPFFEQIQKFHEAPGFENEPFVGVYMTHRPALVIRDLELIKTVMIKKFQYFNNRVLQTDPHNDALGYKNLFFARSPGWRELRTKISPVFTSGKIKQMYPLMVKIGKNLQDSAERLGSGTEVQVKDLCSRFTTDLIATIAFGVEANALQDAKSEFFYHNRAIFSLTLSRGIDFAIIFMIPALASLARVKLFSRETTKFIRSSVNYVLKERERTGEKRNDLIDILLALKREAAANPGKMSKEVDLDYLVAQAAVFQTAGFETSASTMTMTLYELAKNEALQDRLRQEIVDFFGDEDHISYERIQEMPYLSQVVNETLRKYPIVGYIERECSQPAEGERFTLEPFHNMELPHGMSIYMSTVAVHRDPQYWPDPEKYDPERFNSSNRDNLNMDAYMPFGVGPRNCIGMRLGLLQSKLGLVHILRNHRFHTCDKTIKKIEWAPTSPVMASKRDIILRVEKVSGKKDFGQK", "length": 514 }, "evidence": [ { "id": "RGD:628709", "url": "https://alliancegenome.org/gene/RGD:628709#orthology", "database": "AGR" }, { "id": "HGNC:2638", "url": "https://alliancegenome.org/gene/HGNC:2638#orthology", "database": "AGR" }, { "id": "HGNC:2637", "url": "https://alliancegenome.org/gene/HGNC:2637#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050604-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050604-1#orthology", "database": "AGR" }, { "id": "SGD:S000001049", "url": "https://alliancegenome.org/gene/SGD:S000001049#orthology", "database": "AGR" }, { "id": "RGD:1595919", "url": "https://alliancegenome.org/gene/RGD:1595919#orthology", "database": "AGR" }, { "id": "RGD:708379", "url": "https://alliancegenome.org/gene/RGD:708379#orthology", "database": "AGR" }, { "id": "RGD:708392", "url": "https://alliancegenome.org/gene/RGD:708392#orthology", "database": "AGR" }, { "id": "RGD:628626", "url": "https://alliancegenome.org/gene/RGD:628626#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VB31-1", "protein_name": "Probable cytochrome P450 6a18", "gene_name": "Cyp6a18", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MQLTYFLFQVAVALLAIVTYILHRKLTYFKRRGIPYDKPHPLRGNMEGYKKTRTVHEIHQEYYNKYRNSKAPFVGFYLFQKPAAFVIDLELAKQILIKNFSNFTDKGIYYNEKDDPMSAHLFNLDGPQWRLLRSKLSSTFTSGKMKFMYPTVVSVAEEFMAVMHEKVSENSILDVRDLVARFTVDVIGTCAFGIKCNSLRDEKAEFLHFGRRALLDSRHGNLVSGLMRSYPNLARRLGLCRNTAQIQEFYQRIVKETVTLREKENIKRNDFMDMLIGLKNQKNMTLENGEVVKGLTMDEIVAQAFVFFIAGFDTSSSTMGFALYELAKNPSIQDKVRAELGQVLEQHDQKFTYECIKDLKYLDQVINETLRHYTIVPNVDRVAAKRFVVPGNPKFVIEAGQSVIIPSSAIHHDPSIYPEPNEFRPERFSPEESAKRPSVAWLPFGEGPRNCIGLRFGQMQARIGLAMLIKNFTFSPCSATPDPLTFDPHSAILLGIKGGIQLKVEAI", "length": 507 }, "evidence": [ { "id": "RGD:628709", "url": "https://alliancegenome.org/gene/RGD:628709#orthology", "database": "AGR" }, { "id": "HGNC:2638", "url": "https://alliancegenome.org/gene/HGNC:2638#orthology", "database": "AGR" }, { "id": "HGNC:2637", "url": "https://alliancegenome.org/gene/HGNC:2637#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050604-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050604-1#orthology", "database": "AGR" }, { "id": "SGD:S000001049", "url": "https://alliancegenome.org/gene/SGD:S000001049#orthology", "database": "AGR" }, { "id": "RGD:1595919", "url": "https://alliancegenome.org/gene/RGD:1595919#orthology", "database": "AGR" }, { "id": "RGD:708392", "url": "https://alliancegenome.org/gene/RGD:708392#orthology", "database": "AGR" }, { "id": "RGD:628626", "url": "https://alliancegenome.org/gene/RGD:628626#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VCW1-1", "protein_name": "Probable cytochrome P450 6d4", "gene_name": "Cyp6d4", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFSLILLAVTLLTLAWFYLKRHYEYWERRGFPFEKHSGIPFGCLDSVWRQEKSMGLAIYDVYVKSKERVLGIYLLFRPAVLIRDADLARRVLAQDFASFHDRGVYVDEERDPLSANIFSLRGQSWRSMRHMLSPCFTSGKLKSMFSTSEDIGDKMVAHLQKELPEEGFKEVDIKKVMQNYAIDIIASTIFGLDVNSFENPDNKFRKLVSLARANNRFNAMFGMMIFLVPSIAQFLFRIGFKNPVGLAMLQIVKETVEYREKHGIVRKDLLQLLIQLRNTGKIDENDEKSFSIQKTPDGHIKTISLEAITAQAFIFYIAGQETTGSTAAFTIYELAQYPELLKRLQDEVDETLAKNDGKITYDSLNKMEFLDLCVQETIRKYPGLPILNRECTQDYTVPDTNHVIPKGTPVVISLYGIHHDAEYFPDPETYDPERFSEESRNYNPTAFMPFGEGPRICIAQRMGRINSKLAIIKILQNFNVEVMSRSEIEFENSGIALIPKHGVRVRLSKRVPKLS", "length": 515 }, "evidence": [ { "id": "RGD:628709", "url": "https://alliancegenome.org/gene/RGD:628709#orthology", "database": "AGR" }, { "id": "HGNC:2638", "url": "https://alliancegenome.org/gene/HGNC:2638#orthology", "database": "AGR" }, { "id": "HGNC:2637", "url": "https://alliancegenome.org/gene/HGNC:2637#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050604-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050604-1#orthology", "database": "AGR" }, { "id": "SGD:S000001049", "url": "https://alliancegenome.org/gene/SGD:S000001049#orthology", "database": "AGR" }, { "id": "RGD:1595919", "url": "https://alliancegenome.org/gene/RGD:1595919#orthology", "database": "AGR" }, { "id": "RGD:708379", "url": "https://alliancegenome.org/gene/RGD:708379#orthology", "database": "AGR" }, { "id": "RGD:708392", "url": "https://alliancegenome.org/gene/RGD:708392#orthology", "database": "AGR" }, { "id": "RGD:628626", "url": "https://alliancegenome.org/gene/RGD:628626#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VFP1-1", "protein_name": "Probable cytochrome P450 6d5", "gene_name": "Cyp6d5", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MIGIYLLIAAVTLLYVYLKWTFSYWDRKGFPSTGVSIPFGALESVTKGKRSFGMAIYDMYKSTKEPVIGLYLTLRPALLVRDAQLAHDVLVKDFASFHDRGVYVDEKNDPMSASLFQMEGASWRALRNKLTPSFTSGKLKAMFETSDSVGDKLVDSIRKQLPANGAKELELKKLMATYAIDIIATTIFGLDVDSFADPNNEFQIISKKVNRNNIEDIIRGTSSFLYPGLEKFFVKIGWKQEATERMRELSNRTVDLREQNNIVRKDLLQLLLQLRNQGKINTDDNIWSAESTKNGVKSMSKDLIAGQLFLFYVAGYETTASTTSFTLYELTQNPEVMEKAKEDVRSAIEKHGGKLTYDAISDMKYLEACILETARKYPALPLLNRICTKDYPVPDSKLVIQKGTPIIISLIGMHRDEEYFPDPLAYKPERYLENGKDYTQAAYLPFGEGPRMCIGARMGKVNVKIAIAKVLSNFDLEIRKEKCEIEFGVYGIPLMPKSGVPVRLSLKK", "length": 508 }, "evidence": [ { "id": "RGD:628709", "url": "https://alliancegenome.org/gene/RGD:628709#orthology", "database": "AGR" }, { "id": "HGNC:2637", "url": "https://alliancegenome.org/gene/HGNC:2637#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050604-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050604-1#orthology", "database": "AGR" }, { "id": "SGD:S000001049", "url": "https://alliancegenome.org/gene/SGD:S000001049#orthology", "database": "AGR" }, { "id": "RGD:1595919", "url": "https://alliancegenome.org/gene/RGD:1595919#orthology", "database": "AGR" }, { "id": "RGD:708379", "url": "https://alliancegenome.org/gene/RGD:708379#orthology", "database": "AGR" }, { "id": "RGD:708392", "url": "https://alliancegenome.org/gene/RGD:708392#orthology", "database": "AGR" }, { "id": "RGD:628626", "url": "https://alliancegenome.org/gene/RGD:628626#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VG82-1", "protein_name": "Probable cytochrome P450 9f2", "gene_name": "Cyp9f2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLWEFFALFAIAAALFYRWASANNDFFKDRGIAYEKPVLYFGNMAGMFLRKRAMFDIVCDLYTKGGSKKFFGIFEQRQPLLMVRDPDLIKQITIKDFDHFINHRNVFATSSDDDPHDMSNLFGSSLFSMRDARWKDMRSTLSPAFTGSKMRQMFQLMNQVAKEAVDCLKQDDSRVQENELDMKDYCTRFTNDVIASTAFGLQVNSFKDRENTFYQMGKKLTTFTFLQSMKFMLFFALKGLNKILKVELFDRKSTQYFVRLVLDAMKYRQEHNIVRPDMINMLMEARGIIQTEKTKASAVREWSDRDIVAQCFVFFFAGFETSAVLMCFTAHELMENQDVQQRLYEEVQQVDQDLEGKELTYEAIMGMKYLDQVVNEVLRKWPAAIAVDRECNKDITFDVDGQKVEVKKGDVIWLPTCGFHRDPKYFENPMKFDPERFSDENKESIQPFTYFPFGLGQRNCIGSRFALLEAKAVIYYLLKDYRFAPAKKSCIPLELITSGFQLSPKGGFWIKLVQRN", "length": 516 }, "evidence": [ { "id": "RGD:628709", "url": "https://alliancegenome.org/gene/RGD:628709#orthology", "database": "AGR" }, { "id": "HGNC:2638", "url": "https://alliancegenome.org/gene/HGNC:2638#orthology", "database": "AGR" }, { "id": "HGNC:2637", "url": "https://alliancegenome.org/gene/HGNC:2637#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050604-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050604-1#orthology", "database": "AGR" }, { "id": "SGD:S000001049", "url": "https://alliancegenome.org/gene/SGD:S000001049#orthology", "database": "AGR" }, { "id": "RGD:1595919", "url": "https://alliancegenome.org/gene/RGD:1595919#orthology", "database": "AGR" }, { "id": "RGD:708379", "url": "https://alliancegenome.org/gene/RGD:708379#orthology", "database": "AGR" }, { "id": "RGD:708392", "url": "https://alliancegenome.org/gene/RGD:708392#orthology", "database": "AGR" }, { "id": "RGD:628626", "url": "https://alliancegenome.org/gene/RGD:628626#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VRB3-1", "protein_name": "Probable cytochrome P450 6v1", "gene_name": "Cyp6v1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVYSTNILLAIVTILTGVFIWSRRTYVYWQRRRVKFVQPTHLLGNLSRVLRLEESFALQLRRFYFDERFRNEPVVGIYLFHQPALLIRDLQLVRTVLVEDFVSFSNRFAKCDGRSDKMGALSLFLAKQPEWREIRTRLAPAFAGAKLKQMFSLMEEIGCDLEWYLKRLTRDLRRGDAERGAIVSIKDVCDLYNTDMIASIAFGLRSYSLRNTQSEIGSHCQDLFRPNVRRIIDLFVIFYLPKLVPLLRPKLFTEPHAEFLRRVIQLVIEERERGGDLRNDLIEMLLTLKKEADLQQDKSHFTHHRDFLAAQAASFEVAGIETCSASMSFALYELAKQPLMQSRLRREIREAFASNPNGRLTYEAVARMEFLDMVVEETLRKYPIVPLLERECTPINKKRFYSLRPHAECYTRRGMPVFISNLAIHHDPKYWPDPDRFDPERFSAANKALQAPMSYMPFGAGPRNCIGMQIGLLQIKLGLVYFLHQHRVEICDRTVERIQFDAKFALLASEQRIYLKVDCL", "length": 520 }, "evidence": [ { "id": "HGNC:2638", "url": "https://alliancegenome.org/gene/HGNC:2638#orthology", "database": "AGR" }, { "id": "HGNC:2637", "url": "https://alliancegenome.org/gene/HGNC:2637#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050604-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050604-1#orthology", "database": "AGR" }, { "id": "SGD:S000001049", "url": "https://alliancegenome.org/gene/SGD:S000001049#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VVN6-1", "protein_name": "Probable cytochrome P450 312a1", "gene_name": "Cyp312a1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFWLGFGLLLLALSLYLLYVFERQSRIDRLTHKWPAPPALPFIGHLHILAKLVGPHPLRRATEMINEHLHDHRAKLWMGTKLYLVDCNPKDIQALCSAQQLLQKTNDYRVFENWLCEGLFTSGFEKWSHRRKIVMPAFNYTMIKQFVAVFEKQSRILLTNVAKFAESGDQIDFLQLISCFTLDTICETALGVSVGSQSSAKSEYLDAVKSILVIIDKRLKNIFYRNSFIFKRTSHYKREQELIKTLHGFTEGIIQKRIDEINQDAENRNYQSSDAELDGVKRTLCFLDTLLLSKGPDGKPLTVKDIREEVDTIIFGGFDLTATTLNFFMYNMTLHPEHQQRCREEVWSVCGKDKSEPISIEQVRQLEFLEACIKETLRMYPSGPLTARKATANCTINDFFIPKGSDVIISPIYMGRCKDFFPDPMVFKPDRWAIGAEPKIEATTFIPFMAGARSCMGQRYAMVMLKMVLAHLLRNFLFEPLGERQVKLKLNFVITLHTVEPYLCRAKNLD", "length": 510 }, "evidence": [ { "id": "SGD:S000001049", "url": "https://alliancegenome.org/gene/SGD:S000001049#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W130-1", "protein_name": "Cytochrome P450 9c1", "gene_name": "Cyp9c1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVFVELSIFVAFIGLLLYKWSVYTFGYFSKRGVAHEKPIPLLGNIPWSVLMGKESYIKHSIDLHLRLKQHKVYGVFNLRDPLYYLSDPELIRQVGIKNFDTFTNHRKGITEGFNDTSVISKSLLSLRDRRWKQMRSTLTPTFTSLKIRQMFELIHFCNVEAVDFVQRQLDAGTSELELKDFFTRYTNDVIATAAFGIQVNSFKDPNNEFFSIGQRISEFTFWGGLKVMLYILMPKLMKALRVPVMDMNNVDYFKKLVFGAMKYRKEQSIVRPDMIHLLMEAQRQFKAEQEGSAESAAQQDKAEFNDDDLLAQCLLFFSAGFETVATCLSFTSYELMMNPEVQEKLLAEILAVKEQLGEKPLDYDTLMGMKYLNCVVSESLRKWPPAFIVDRMCGSDFQLKDEEGEVVVNLREDDLVHINVGALHHDPDNFPEPEQFRPERFDEEHKHEIRQFTYLPFGVGQRSCIGNRLALMEVKSLIFQLVLRYHLKPTDRTPADMMSSISGFRLLPRELFWCKLESRGPA", "length": 522 }, "evidence": [ { "id": "RGD:628709", "url": "https://alliancegenome.org/gene/RGD:628709#orthology", "database": "AGR" }, { "id": "HGNC:2638", "url": "https://alliancegenome.org/gene/HGNC:2638#orthology", "database": "AGR" }, { "id": "HGNC:2637", "url": "https://alliancegenome.org/gene/HGNC:2637#orthology", "database": "AGR" }, { "id": "RGD:1595919", "url": "https://alliancegenome.org/gene/RGD:1595919#orthology", "database": "AGR" }, { "id": "RGD:708379", "url": "https://alliancegenome.org/gene/RGD:708379#orthology", "database": "AGR" }, { "id": "RGD:708392", "url": "https://alliancegenome.org/gene/RGD:708392#orthology", "database": "AGR" }, { "id": "RGD:628626", "url": "https://alliancegenome.org/gene/RGD:628626#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W223-1", "protein_name": "Probable cytochrome P450 6d2", "gene_name": "Cyp6d2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MWTILLTILIAGLLYRYVKRHYTHWQRLGVDEEPAKIPFGVMDTVMKQERSLGMALADIYARHEGKIVGIYMLNKRSILIRDAQLARQIMTSDFASFHDRGVYVDEDKDPLSANLFNLRGASWRNLRQKLTPSFSSGKIKGMFGTIDDVGDKLVQHLEGALDQSDEVEIKDVMTTYAVDIIGSVIFGLEIDSFRNPKNEFREISSSTSRDESLLLKIHNMSMFICPPIAKLMNRLGYESRILTSLRDMMKRTIEFREEHNVVRKDMLQLLIRLRNTGKIGEDDDQVWDMETAQEQLKSMSIEKIAAQAFLFYVAGSESTAAASAFTLYELSMYPELLKEAQEEVDAVLMKHNLKPKDRFTYEAVQDLKFLDICIMETIRKYPGLPFLNRECTEDYPVPGTNHIIAKGTPILISLFGMQRDPVYFPNPNGYDPHRFDSNNMNYDQAAYMPFGEGPRHCIALRMGKVNSKVAVAKILANFDLVQSPRKEVEFRFDAAPVLVTKEPLKLRLTKRK", "length": 512 }, "evidence": [ { "id": "HGNC:2638", "url": "https://alliancegenome.org/gene/HGNC:2638#orthology", "database": "AGR" }, { "id": "HGNC:2637", "url": "https://alliancegenome.org/gene/HGNC:2637#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050604-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050604-1#orthology", "database": "AGR" }, { "id": "SGD:S000001049", "url": "https://alliancegenome.org/gene/SGD:S000001049#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "X2J9F6", "url": "https://www.uniprot.org/uniprotkb/X2J9F6" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "X2J9F6", "url": "https://www.uniprot.org/uniprotkb/X2J9F6" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "X2J9F6", "url": "https://www.uniprot.org/uniprotkb/X2J9F6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "X2J9F6", "url": "https://www.uniprot.org/uniprotkb/X2J9F6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 211, "end_pos": 213, "annotation": "n_glycosylation_sequon" }, { "start_pos": 305, "end_pos": 307, "annotation": "n_glycosylation_sequon" }, { "start_pos": 328, "end_pos": 330, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 211, "end_pos": 213 }, { "start_pos": 305, "end_pos": 307 }, { "start_pos": 328, "end_pos": 330 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "X2JA66-1", "uniprot_ac": "X2JA66", "uniprot_id": "X2JA66_DROME", "mass": { "chemical_mass": 7443.0, "monoisotopic_mass": 7443.0 }, "refseq": { "ac": "NP_001285848", "name": "uncharacterized protein, isoform A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285848" }, "gene_names": [ { "name": "Dmel\\CG45011", "type": "recommended", "evidence": [ { "id": "X2JA66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/X2JA66" } ] }, { "name": "CG45011", "type": "synonym", "evidence": [ { "id": "NP_001285848", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285848" }, { "id": "X2JA66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/X2JA66" } ] }, { "name": "Dmel\\CG45011", "type": "synonym", "evidence": [ { "id": "NP_001285848", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285848" } ] }, { "name": "Dmel_CG45011", "type": "synonym", "evidence": [ { "id": "X2JA66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/X2JA66" } ] } ], "protein_names": [ { "name": "Kazal-like domain-containing protein", "type": "recommended", "evidence": [ { "id": "X2JA66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/X2JA66/entry#names_and_taxonomy" } ] }, { "name": "CG45011-PA", "type": "synonym", "evidence": [ { "id": "NP_001285848", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285848" } ] }, { "name": "uncharacterized protein, isoform A", "type": "synonym", "evidence": [ { "id": "NP_001285848", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285848" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "X2JA66", "url": "https://www.uniprot.org/uniprotkb/X2JA66" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "Dmel\\CG45011", "url": "https://www.uniprot.org/uniprotkb/X2JA66", "locus": { "chromosome": "2L", "start_pos": 11834497, "end_pos": 11834086, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0266363", "url": "https://www.ensemblgenomes.org/id/FBgn0266363" } ] } } ], "crossref": [ { "id": "FB:FBgn0266363", "url": "https://alliancegenome.org/gene/FB:FBgn0266363", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0266363", "url": "https://bgee.org/?page=gene&gene_id=FBgn0266363", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00104", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00104", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0266363", "url": "https://flybase.org/reports/FBgn0266363", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "19835723", "url": "https://www.ncbi.nlm.nih.gov/gene/19835723", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG45011", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG45011", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NICELQC", "url": "https://omabrowser.org/oma/group/NICELQC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "X2JA66", "url": "https://www.orthodb.org/?gene=X2JA66", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF00050", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00050", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001285848", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001285848", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "X2JA66", "url": "https://www.uniprot.org/uniprotkb/X2JA66", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "X2JA66-1", "url": "https://www.uniprot.org/uniprotkb/X2JA66-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYSPIFIALCLLAFVVLTEAQVTRPLCPCPRIYFPVCGSDHVTYTNSCELKCAAQIKLIYVVKAGRC", "length": 67, "header": "tr|X2JA66-1|X2JA66_DROME Isoform 1 of Kazal-like domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG45011 PE=4 SV=1 CANONICAL=X2JA66-1" }, "isoforms": [ { "isoform_ac": "X2JA66-1", "url": "https://www.uniprot.org/uniprotkb/X2JA66/entry#X2JA66-1", "sequence": { "sequence": "MYSPIFIALCLLAFVVLTEAQVTRPLCPCPRIYFPVCGSDHVTYTNSCELKCAAQIKLIYVVKAGRC", "length": 67, "header": "tr|X2JA66-1|X2JA66_DROME Isoform 1 of Kazal-like domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dmel\\CG45011 PE=4 SV=1 CANONICAL=X2JA66-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "X2JA66", "url": "https://www.uniprot.org/uniprotkb/X2JA66" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "X2JA66", "url": "https://www.uniprot.org/uniprotkb/X2JA66" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "X2JA66", "url": "https://www.uniprot.org/uniprotkb/X2JA66" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "X2JA66", "url": "https://www.uniprot.org/uniprotkb/X2JA66" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "X2JA66", "url": "https://www.uniprot.org/uniprotkb/X2JA66" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "X2JA66", "url": "https://www.uniprot.org/uniprotkb/X2JA66" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "X2JA66", "url": "https://www.uniprot.org/uniprotkb/X2JA66" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "X2JA66", "url": "https://www.uniprot.org/uniprotkb/X2JA66" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "X2JA66", "url": "https://www.uniprot.org/uniprotkb/X2JA66" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "X2JA66", "url": "https://www.uniprot.org/uniprotkb/X2JA66" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "X2JA66", "url": "https://www.uniprot.org/uniprotkb/X2JA66" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], 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"https://www.ncbi.nlm.nih.gov/protein/NP_725287" } ] }, { "name": "immune induced molecule 5", "type": "synonym", "evidence": [ { "id": "NP_725287", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_725287" } ] }, { "name": "immune induced molecule 6", "type": "synonym", "evidence": [ { "id": "NP_725287", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_725287" } ] }, { "name": "immune induced molecule 8", "type": "synonym", "evidence": [ { "id": "NP_725287", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_725287" } ] }, { "name": "immune induced molecule prepropeptide", "type": "synonym", "evidence": [ { "id": "NP_725287", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_725287" } ] }, { "name": "immune-induced molecule 10", "type": "synonym", "evidence": [ { "id": "NP_725287", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_725287" } ] }, { "name": "molecule 10", "type": "synonym", "evidence": [ { "id": "NP_725287", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_725287" } ] } ], "function": [ { "annotation": "Secreted immune-induced peptides induced by Toll signaling (PubMed:34432851, PubMed:9736738). Has a significant role in resistance to infection by the entomopathogenic fungus B.bassiana R444 and weak antifungal activity against M.rileyi PHP1705 (PubMed:34432851). In adult males, activity appears to be important for neuromuscular processes that mediate correct wing posture upon Toll activation (PubMed:34432851).", "evidence": [ { "database": "UniProtKB", "id": "C0HM00", "url": "https://www.uniprot.org/uniprotkb/C0HM00#function" }, { "database": "PubMed", "id": "34432851", "url": "https://glygen.org/publication/PubMed/34432851" }, { "database": "PubMed", "id": "9736738", "url": "https://glygen.org/publication/PubMed/9736738" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "C0HM00", "url": "https://www.uniprot.org/uniprotkb/C0HM00" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "BaraA2", "url": "https://www.uniprot.org/uniprotkb/C0HM00", "locus": { "chromosome": "2R", "start_pos": 13408358, 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"MKSFGLIALAICGVICVAAEPQHTYDGRNGPHVFGSPGNQVYIRGQNEGTYSVPGVGGQFQNAPQRGEHVYTDEAGNTFVNRKNAGGPASHTISGPNFSAKNLGPNGAKSVGIPQRARRSPQFHVERPGRTVDVGNGGFYIQRGRRSPQLHVARPDRTVTIGNGGVYIQRSRRSPQFHVERPDRTVDFGNGGFSAQRFRRGINDARVQGENFVARDDQAGIWDNNVSVWKRPDGRTVTIDRNGHTIVSGRGRPAQHY", "length": 257, "header": "sp|C0HM00-1|BARA2_DROME Isoform 1 of Baramicin A2 OS=Drosophila melanogaster OX=7227 GN=BaraA2 PE=1 SV=1 CANONICAL=C0HM00-1" }, "isoforms": [ { "isoform_ac": "C0HM00-1", "url": "https://www.uniprot.org/uniprotkb/C0HM00/entry#C0HM00-1", "sequence": { "sequence": "MKSFGLIALAICGVICVAAEPQHTYDGRNGPHVFGSPGNQVYIRGQNEGTYSVPGVGGQFQNAPQRGEHVYTDEAGNTFVNRKNAGGPASHTISGPNFSAKNLGPNGAKSVGIPQRARRSPQFHVERPGRTVDVGNGGFYIQRGRRSPQLHVARPDRTVTIGNGGVYIQRSRRSPQFHVERPDRTVDFGNGGFSAQRFRRGINDARVQGENFVARDDQAGIWDNNVSVWKRPDGRTVTIDRNGHTIVSGRGRPAQHY", "length": 257, "header": "sp|C0HM00-1|BARA2_DROME Isoform 1 of Baramicin A2 OS=Drosophila melanogaster OX=7227 GN=BaraA2 PE=1 SV=1 CANONICAL=C0HM00-1" }, "locus": { "chromosome": "2R", "start_pos": 13407011, "end_pos": 13408103, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0087654", "url": "https://www.ensemblgenomes.org/id/FBtr0087654" }, { "database": "Ensembl Peptide", "id": "FBpp0086780", "url": "https://www.ensemblgenomes.org/id/FBpp0086780" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 225, "start_aa": "Asn", "end_pos": 225, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn225", "evidence": [ { "id": "C0HM00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/C0HM00#ptm_processing" } ], "filter_code": "00100000000000000000.00010000000000.0.01000" }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], 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C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "C0HM00", "url": "https://www.uniprot.org/uniprotkb/C0HM00" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "C0HM00", "url": "https://www.uniprot.org/uniprotkb/C0HM00" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "Identification of new immune induced molecules in the haemolymph of Drosophila melanogaster by 2D-nanoLC MS/MS.", "journal": "J. Insect Physiol.", "date": "2006", "authors": "Verleyen Peter, Baggerman Geert, D'Hertog Wannes, Vierstraete Evy, Husson Steven J, Schoofs Liliane", "evidence": [ { "database": "UniProtKB", "id": "C0HM00", "url": "https://www.uniprot.org/uniprotkb/C0HM00" } ], "reference": [ { "type": "PubMed", "id": "16510152", "url": "https://glygen.org/publication/PubMed/16510152" } ] }, { "title": "The Drosophila Baramicin polypeptide gene protects against fungal infection.", "journal": "PLoS pathogens", "date": "2021", "authors": "Hanson MA, Cohen LB, Marra A, Iatsenko I, Wasserman SA, Lemaitre B", "evidence": [ { "database": "UniProtKB", "id": "C0HM00", "url": "https://www.uniprot.org/uniprotkb/C0HM00" } ], "reference": [ { "type": "PubMed", "id": "34432851", "url": "https://glygen.org/publication/PubMed/34432851" } ] }, { "title": "Differential display of peptides induced during the immune response of Drosophila: a matrix-assisted laser desorption ionization time-of-flight mass spectrometry 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Has a significant role in resistance to infection by the entomopathogenic fungus B.bassiana R444 and weak antifungal activity against M.rileyi PHP1705 (PubMed:34432851). In adult males, activity appears to be important for neuromuscular processes that mediate correct wing posture upon Toll activation (PubMed:34432851).", "evidence": [ { "database": "UniProtKB", "id": "C0HLZ9", "url": "https://www.uniprot.org/uniprotkb/C0HLZ9#function" }, { "database": "PubMed", "id": "34432851", "url": "https://glygen.org/publication/PubMed/34432851" }, { "database": "PubMed", "id": "9736738", "url": "https://glygen.org/publication/PubMed/9736738" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "C0HLZ9", "url": "https://www.uniprot.org/uniprotkb/C0HLZ9" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "BaraA1", "url": "https://www.uniprot.org/uniprotkb/C0HLZ9", "locus": { "chromosome": "2R", "start_pos": 13413085, 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C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "C0HLZ9", "url": "https://www.uniprot.org/uniprotkb/C0HLZ9" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { 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Boutros M, Vingron M, Sauer F, Hoheisel J D, Paro R", "evidence": [ { "database": "UniProtKB", "id": "C0HLZ9", "url": "https://www.uniprot.org/uniprotkb/C0HLZ9" } ], "reference": [ { "type": "PubMed", "id": "14709175", "url": "https://glygen.org/publication/PubMed/14709175" } ] }, { "title": "Identification of new immune induced molecules in the haemolymph of Drosophila melanogaster by 2D-nanoLC MS/MS.", "journal": "J. Insect Physiol.", "date": "2006", "authors": "Verleyen Peter, Baggerman Geert, D'Hertog Wannes, Vierstraete Evy, Husson Steven J, Schoofs Liliane", "evidence": [ { "database": "UniProtKB", "id": "C0HLZ9", "url": "https://www.uniprot.org/uniprotkb/C0HLZ9" } ], "reference": [ { "type": "PubMed", "id": "16510152", "url": "https://glygen.org/publication/PubMed/16510152" } ] }, { "title": "The Drosophila Baramicin polypeptide gene protects against fungal infection.", "journal": "PLoS pathogens", "date": "2021", "authors": "Hanson MA, Cohen LB, Marra A, Iatsenko I, Wasserman SA, Lemaitre B", "evidence": [ { "database": "UniProtKB", "id": "C0HLZ9", "url": "https://www.uniprot.org/uniprotkb/C0HLZ9" } ], "reference": [ { "type": "PubMed", "id": "34432851", "url": "https://glygen.org/publication/PubMed/34432851" } ] }, { "title": "Differential display of peptides induced during the immune response of Drosophila: a matrix-assisted laser desorption ionization time-of-flight mass spectrometry 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"common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "side-II", "url": "https://www.uniprot.org/uniprotkb/A0A9F2H0X3", "locus": { "chromosome": "2L", "start_pos": 14907489, "end_pos": 14972300, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0259213", "url": "https://www.ensemblgenomes.org/id/FBgn0259213" } ] } } ], "crossref": [ { "id": "FB:FBgn0259213", "url": "https://alliancegenome.org/gene/FB:FBgn0259213", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A9F2H0X3", "url": "https://alphafold.ebi.ac.uk/entry/A0A9F2H0X3", "database": "AlphaFoldDB", "categories": [] }, { "id": "FBgn0259213", "url": "https://bgee.org/?page=gene&gene_id=FBgn0259213", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00096", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00096", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0259213", "url": "https://flybase.org/reports/FBgn0259213", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "3346206", "url": "https://www.ncbi.nlm.nih.gov/gene/3346206", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q59DZ1", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q59DZ1*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013162", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013162", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG42313", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG42313", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MPQKCLH", "url": "https://omabrowser.org/oma/group/MPQKCLH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9F2H0X3", "url": "https://www.orthodb.org/?gene=A0A9F2H0X3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q59DZ1", "url": "https://www.orthodb.org/?gene=Q59DZ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23278", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23278", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23278:SF31", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23278:SF31", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08205", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08205", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001400995", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001400995", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9F2H0X3", "url": "https://www.uniprot.org/uniprotkb/A0A9F2H0X3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9F2H0X3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9F2H0X3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q59DZ1", "url": "https://www.uniprot.org/uniprotkb/Q59DZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q59DZ1-1", "url": "https://www.uniprot.org/uniprotkb/Q59DZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVLLLAMALLMPVTLARLHSTSGVGMSGGGSSMGPGGGGSGSGGISSKDSHVKTKDIDAVEGKSVSLPCPITEPLDNVYMVLWFRDNAGIPLYSFDVRDKESREQPRHWSAPEVFGSRAKFHFDSQPATLEIKDIKRHDQGIYRCRVDFRTSQTQSFRFNLSVIILPEQPIIMDRWGRQLNGTQLGPKQEGDDIVITCRVVGGRPQPQVRWLVNGLLVDNQNEHNSGDVIENRLLWPSVQRNDLNSVFTCQALNTQLDKPKEKSFILDMHLKPLVVKILEPPSSMIADRRYEVSCESSGSRPNAIITWYKGKRQLRRTKDDISKNSTRSELSFVPTTDDDGKSITCRAENPNVNGLYLETMWKLNVVYPPLVTLRLGSTLTPDDIKEGDDVYFECHVQSNPQWRKLLWLHNGIHLEHNTSARVIRSNQSLVLQKITKHYAGNYACSAINDEGETVSNQLPLRVKYTPMCKHADRVILIGASKDETVEVVCEIQADPPPRTFRWKFNNSGETLDVGSERFSVNGSRSILKYTPVTDQDYGTLSCWASNEVGTQQHPCLFQVVLAALPNAVSNCTVFNRTELSVDIQCIPGYDGGLPQIFVLEMFSTRTGITRFNLSNAEEALFSLENLDTLTSMMVQENNSLRLRIYSYNQKGRSAAYLLTDFIIGSTAYKTDDDVTLTLSPVIVGSVLTIIIIGVAIAIRIFVVTFVHNLRRNRHHGSKATAAGVTAQPSDVFKGGNLEKPRWQHTDIKTKSSEDLVEDERDPDVIPSQYVGGSSAGSSGSNASNVGSTTAGTATGSSTSTAVVANANAAASAMAGPGGATSSASATDGHQFASGTAAAGGGASKWSPNGNVTTTMLTGDAVNATVTYNQINAQRAQLLAAVAAVGGGCSSTVISPSSSILGGLGKPLGMGMGMGLGMGVGGTVIGSPTSLSSTATLAAHLQPAHSSGVGTLPPGLGSGGGYILNAYASGRLHHPPGGGVPGGATHTATLNRHHHQQQQLHHHPHHQQPHHSGSSLLMGSAGSVMGVVGSTTTATTSCNSSQDLDDNININAIKDCLMTQRVPESCV", "length": 1067, "header": "tr|A0A9F2H0X3-1|A0A9F2H0X3_DROME Isoform 1 of Sidestep II, isoform C OS=Drosophila melanogaster OX=7227 GN=side-II PE=4 SV=1 CANONICAL=A0A9F2H0X3-1" }, "isoforms": [ { "isoform_ac": "A0A9F2H0X3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9F2H0X3/entry#A0A9F2H0X3-1", "sequence": { "sequence": "MVLLLAMALLMPVTLARLHSTSGVGMSGGGSSMGPGGGGSGSGGISSKDSHVKTKDIDAVEGKSVSLPCPITEPLDNVYMVLWFRDNAGIPLYSFDVRDKESREQPRHWSAPEVFGSRAKFHFDSQPATLEIKDIKRHDQGIYRCRVDFRTSQTQSFRFNLSVIILPEQPIIMDRWGRQLNGTQLGPKQEGDDIVITCRVVGGRPQPQVRWLVNGLLVDNQNEHNSGDVIENRLLWPSVQRNDLNSVFTCQALNTQLDKPKEKSFILDMHLKPLVVKILEPPSSMIADRRYEVSCESSGSRPNAIITWYKGKRQLRRTKDDISKNSTRSELSFVPTTDDDGKSITCRAENPNVNGLYLETMWKLNVVYPPLVTLRLGSTLTPDDIKEGDDVYFECHVQSNPQWRKLLWLHNGIHLEHNTSARVIRSNQSLVLQKITKHYAGNYACSAINDEGETVSNQLPLRVKYTPMCKHADRVILIGASKDETVEVVCEIQADPPPRTFRWKFNNSGETLDVGSERFSVNGSRSILKYTPVTDQDYGTLSCWASNEVGTQQHPCLFQVVLAALPNAVSNCTVFNRTELSVDIQCIPGYDGGLPQIFVLEMFSTRTGITRFNLSNAEEALFSLENLDTLTSMMVQENNSLRLRIYSYNQKGRSAAYLLTDFIIGSTAYKTDDDVTLTLSPVIVGSVLTIIIIGVAIAIRIFVVTFVHNLRRNRHHGSKATAAGVTAQPSDVFKGGNLEKPRWQHTDIKTKSSEDLVEDERDPDVIPSQYVGGSSAGSSGSNASNVGSTTAGTATGSSTSTAVVANANAAASAMAGPGGATSSASATDGHQFASGTAAAGGGASKWSPNGNVTTTMLTGDAVNATVTYNQINAQRAQLLAAVAAVGGGCSSTVISPSSSILGGLGKPLGMGMGMGLGMGVGGTVIGSPTSLSSTATLAAHLQPAHSSGVGTLPPGLGSGGGYILNAYASGRLHHPPGGGVPGGATHTATLNRHHHQQQQLHHHPHHQQPHHSGSSLLMGSAGSVMGVVGSTTTATTSCNSSQDLDDNININAIKDCLMTQRVPESCV", "length": 1067, "header": "tr|A0A9F2H0X3-1|A0A9F2H0X3_DROME Isoform 1 of Sidestep II, isoform C OS=Drosophila melanogaster OX=7227 GN=side-II PE=4 SV=1 CANONICAL=A0A9F2H0X3-1" }, "locus": {} }, { "isoform_ac": "Q59DZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9F2H0X3/entry#Q59DZ1-1", "sequence": { "sequence": "MVLLLAMALLMPVTLARLHSTSGVGMSGGGSSMGPGGGGSGSGGISSKDSHVKTKDIDAVEGKSVSLPCPITEPLDNVYMVLWFRDNAGIPLYSFDVRDKESREQPRHWSAPEVFGSRAKFHFDSQPATLEIKRHDQGIYRCRVDFRTSQTQSFRFNLSVIILPEQPIIMDRWGRQLNGTQLGPKQEGDDIVITCRVVGGRPQPQVRWLVNGLLVDNQNEHNSGDVIENRLLWPSVQRNDLNSVFTCQALNTQLDKPKEKSFILDMHLKPLVVKILEPPSSMIADRRYEVSCESSGSRPNAIITWYKGKRQLRRTKDDISKNSTRSELSFVPTTDDDGKSITCRAENPNVNGLYLETMWKLNVVYPPLVTLRLGSTLTPDDIKEGDDVYFECHVQSNPQWRKLLWLHNGIHLEHNTSARVIRSNQSLVLQKITKHYAGNYACSAINDEGETVSNQLPLRVKYTPMCKHADRVILIGASKDETVEVVCEIQADPPPRTFRWKFNNSGETLDVGSERFSVNGSRSILKYTPVTDQDYGTLSCWASNEVGTQQHPCLFQVVLAALPNAVSNCTVFNRTELSVDIQCIPGYDGGLPQIFVLEMFSTRTGITRFNLSNAEEALFSLENLDTLTSMMVQENNSLRLRIYSYNQKGRSAAYLLTDFIIGSTAYKTDDDVTLTLSPVIVGSVLTIIIIGVAIAIRIFVVTFVHNLRRNRHHGSKATAAGVTAQPSDVFKGGNLEKPRWQHTDIKTKSSEDLVEDERDPDVIPSQYVGGSSAGSSGSNASNVGSTTAGTATGSSTSTAVVANANAAASAMAGPGGATSSASATDGHQFASGTAAAGGGASKWSPNGNVTTTMLTGDAVNATVTYNQINAQRAQLLAAVAAVGGGCSSTVISPSSSILGGLGKPLGMGMGMGLGMGVGGTVIGSPTSLSSTATLAAHLQPAHSSGVGTLPPGLGSGGGYILNAYASGRLHHPPGGGVPGGATHTATLNRHHHQQQQLHHHPHHQQPHHSGSSLLMGSAGSVMGVVGSTTTATTSCNSSQDLDDNININAIKDCLMTQRVPESCV", "length": 1064, "header": "tr|Q59DZ1-1|A0A9F2H0X3_DROME Computationally mapped isoform of Sidestep II, isoform C OS=Drosophila melanogaster OX=7227 GN=side-II PE=4 SV=3 CANONICAL=A0A9F2H0X3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q59DZ1", "url": "https://www.uniprot.org/uniprotkb/Q59DZ1" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q59DZ1", "url": "https://www.uniprot.org/uniprotkb/Q59DZ1" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q59DZ1", "url": "https://www.uniprot.org/uniprotkb/Q59DZ1" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q59DZ1", "url": "https://www.uniprot.org/uniprotkb/Q59DZ1" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q59DZ1", "url": "https://www.uniprot.org/uniprotkb/Q59DZ1" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q59DZ1", "url": "https://www.uniprot.org/uniprotkb/Q59DZ1" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q59DZ1", "url": "https://www.uniprot.org/uniprotkb/Q59DZ1" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q59DZ1", "url": "https://www.uniprot.org/uniprotkb/Q59DZ1" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q59DZ1", "url": "https://www.uniprot.org/uniprotkb/Q59DZ1" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q59DZ1", "url": "https://www.uniprot.org/uniprotkb/Q59DZ1" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q59DZ1", "url": "https://www.uniprot.org/uniprotkb/Q59DZ1" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG42313", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG42313", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A9F2H0X3", "url": "https://www.uniprot.org/uniprotkb/A0A9F2H0X3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1039, "end_pos": 1041, "annotation": "n_glycosylation_sequon" }, { "start_pos": 160, "end_pos": 162, "annotation": "n_glycosylation_sequon" }, { "start_pos": 181, "end_pos": 183, "annotation": "n_glycosylation_sequon" }, { "start_pos": 325, "end_pos": 327, "annotation": "n_glycosylation_sequon" }, { "start_pos": 418, "end_pos": 420, "annotation": "n_glycosylation_sequon" }, { "start_pos": 427, "end_pos": 429, "annotation": 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"https://www.uniprot.org/uniprotkb/A0A9F2H0X3" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 61, "end_pos": 162, "start_aa": "Glu", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1039, "end_pos": 1041 }, { "start_pos": 160, "end_pos": 162 }, { "start_pos": 181, "end_pos": 183 }, { "start_pos": 325, "end_pos": 327 }, { "start_pos": 418, "end_pos": 420 }, { "start_pos": 427, "end_pos": 429 }, { "start_pos": 506, "end_pos": 508 }, { "start_pos": 522, "end_pos": 524 }, { "start_pos": 571, "end_pos": 573 }, { "start_pos": 576, "end_pos": 578 }, { "start_pos": 613, "end_pos": 615 }, { "start_pos": 638, "end_pos": 640 }, { "start_pos": 782, "end_pos": 784 }, { "start_pos": 851, "end_pos": 853 }, { "start_pos": 863, "end_pos": 865 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"https://www.uniprot.org/uniprotkb/A0ACA5YM07" } ] }, { "name": "Dmel\\CG31038", "type": "synonym", "evidence": [ { "id": "NP_001400985", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001400985" }, { "id": "A0ACA5YM07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ACA5YM07" } ] }, { "name": "Dmel_CG31038", "type": "synonym", "evidence": [ { "id": "A0ACA5YM07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ACA5YM07" } ] } ], "protein_names": [ { "name": "CG31038-PI", "type": "synonym", "evidence": [ { "id": "NP_001400985", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001400985" } ] }, { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0ACA5YM07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ACA5YM07/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein, isoform I", "type": "synonym", "evidence": [ { "id": "NP_001400985", 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"https://bgee.org/?page=gene&gene_id=FBgn0051038", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0051038", "url": "https://flybase.org/reports/FBgn0051038", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "43535", "url": "https://www.ncbi.nlm.nih.gov/gene/43535", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9VAE7", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VAE7*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR039499", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039499", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041426", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041426", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG31038", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG31038", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GNCTRIN", "url": "https://omabrowser.org/oma/group/GNCTRIN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A0B4KHV6", "url": "https://www.orthodb.org/?gene=A0A0B4KHV6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A0B4KI58", "url": "https://www.orthodb.org/?gene=A0A0B4KI58", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q9VAE7", "url": "https://www.orthodb.org/?gene=Q9VAE7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46949", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46949", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46949:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46949:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14854", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14854", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17906", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17906", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001400985", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001400985", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A0B4KHV6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHV6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0B4KHV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHV6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0B4KI58", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI58", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0B4KI58-1", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KI58-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ACA5YM07", "url": "https://www.uniprot.org/uniprotkb/A0ACA5YM07", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ACA5YM07-1", "url": "https://www.uniprot.org/uniprotkb/A0ACA5YM07-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VAE7", "url": "https://www.uniprot.org/uniprotkb/Q9VAE7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VAE7-1", "url": "https://www.uniprot.org/uniprotkb/Q9VAE7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATTAAGSAATTTNTMVVKRPGPPVPPRPKAAAQLANGAGAPPIIQKKPTFVSQLSAVGRTLVYKSPTVNLPKKQAQTQTPTTAVPTPPVKPLKLRKAPDVPTAKPRDSMTSVVTVNRHNSISVIGSTPQTTPRKDTRLSLGKVDFERAGLQPASQPLPRPRKIVQVPVATLDVEDIPVVAPSPSSNGLFRRSKTTLDGSQKDSASSPHNGGGFLSGRTVEIKNNLKNAAERLFSEIIINQSQKQAATDTTIITKHEALKQESDVLAIQSSGNCMRINVNGGQTSTMKSSISVGNTPQKKQAFHEMLISELAAMRNKSCSLEQLPTAKSPPPTTSTPKSVASRRRYNSIDDADTEDVDADNVEDADGDVDEEDTLTYAVNKSLKENIGKEGSSSRKRCPSGCSTDSSPYGTERSQRIRTSDWIEVGDNGTAVTLTSCHISLEDSGMEDEERLDDMSSGVGDSWDSVKEAESEKRSRNGKRGNSACELPPLPKSLIGFNKLLCSDSGLLSDVEGNNNSSDGSRKPNDNLAVETQDTKEHATDKSLPSSPNGNTSIPPMLVAKSEAKSPSLSAKGNPQAVEAGSTLDAQIATLRKEMNGLRQLDLSLLSQLWVLNESIQEFRALIEDQENEDEDDEVEVEVGNELDEEGNSRVSSSIESVRLEGGADGTSKHLGTIPKVITTQPKVLRDSLATASKDQKPVPRMRSAPPPPPPAVLQSLSLERKPPAPSRPTXCYLSDFLAGVRMVMCKAIVSDVPASSASASLGGDGAPLGRDAQSCLGNQTGQVLQA", "length": 787, "header": "tr|A0ACA5YM07-1|A0ACA5YM07_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=CG31038 PE=3 SV=1 CANONICAL=A0ACA5YM07-1" }, "isoforms": [ { "isoform_ac": "A0A0B4KHV6-1", "url": "https://www.uniprot.org/uniprotkb/A0ACA5YM07/entry#A0A0B4KHV6-1", "sequence": { "sequence": "MSEDLDELFLTPIPAPSAVELQQCILFGFRRRLHPAQIFEECRNAFGPFCPSAQYVAKWYQRFQDGFFNLDEKDDEELRIGHGGTPTTCSDYDDDSDCGEATVLPLILSEMIQRSEEDDDDDGTDGFEKESDDGLDGHVIGYWQGYGYLGGKQRYSWAGTKLGNSACELPPLPKSLIGFNKLLCSDSGLLSDVEGNNNSSDGSRKPNDNLAVETQDTKEHATDKSLPSSPNGNTSIPPMLVAKSEAKSPSLSAKGNPQAVEAGSTLDAQIATLRKEMNGLRQLDLSLLSQLWVLNESIQEFRALIEDQENEDEDDEVEVEVGNELDEEGNSRVSSSIESVRLEGGADGTSKHLGTIPKVITTQPKVLRDSLATASKDQKPVPRMRSAPPPPPPAVLQSLSLERKPPAPSRPT", "length": 412, "header": "tr|A0A0B4KHV6-1|A0ACA5YM07_DROME Computationally mapped isoform of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=CG31038 PE=3 SV=1 CANONICAL=A0ACA5YM07-1" }, "locus": {} }, { "isoform_ac": "A0A0B4KI58-1", "url": "https://www.uniprot.org/uniprotkb/A0ACA5YM07/entry#A0A0B4KI58-1", "sequence": { "sequence": "MFIFPILFVQIVISNVIRSLKRRLAKPLKMSEDLDELFLTPIPAPSAVELQQCILFGFRRRLHPAQIFEECRNAFGPFCPSAQYVAKWYQRFQDGFFNLDEKDDEELRIGHGGTPTTCSDYDDDSDCGEATVLPLILSEMIQRSEEDDDDDGTDGFEKESDDGLDGHVIGYWQGYGYLGGKQSGNSACELPPLPKSLIGFNKLLCSDSGLLSDVEGNNNSSDGSRKPNDNLAVETQDTKEHATDKSLPSSPNGNTSIPPMLVAKSEAKSPSLSAKGNPQAVEAGSTLDAQIATLRKEMNGLRQLDLSLLSQLWVLNESIQEFRALIEDQENEDEDDEVEVEVGNELDEEGNSRVSSSIESVRLEGGADGTSKHLGTIPKVITTQPKVLRDSLATASKDQKPVPRMRSAPPPPPPAVLQSLSLERKPPAPSRPT", "length": 433, "header": "tr|A0A0B4KI58-1|A0ACA5YM07_DROME Computationally mapped isoform of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=CG31038 PE=3 SV=1 CANONICAL=A0ACA5YM07-1" }, "locus": {} }, { "isoform_ac": "A0ACA5YM07-1", "url": "https://www.uniprot.org/uniprotkb/A0ACA5YM07/entry#A0ACA5YM07-1", "sequence": { "sequence": "MATTAAGSAATTTNTMVVKRPGPPVPPRPKAAAQLANGAGAPPIIQKKPTFVSQLSAVGRTLVYKSPTVNLPKKQAQTQTPTTAVPTPPVKPLKLRKAPDVPTAKPRDSMTSVVTVNRHNSISVIGSTPQTTPRKDTRLSLGKVDFERAGLQPASQPLPRPRKIVQVPVATLDVEDIPVVAPSPSSNGLFRRSKTTLDGSQKDSASSPHNGGGFLSGRTVEIKNNLKNAAERLFSEIIINQSQKQAATDTTIITKHEALKQESDVLAIQSSGNCMRINVNGGQTSTMKSSISVGNTPQKKQAFHEMLISELAAMRNKSCSLEQLPTAKSPPPTTSTPKSVASRRRYNSIDDADTEDVDADNVEDADGDVDEEDTLTYAVNKSLKENIGKEGSSSRKRCPSGCSTDSSPYGTERSQRIRTSDWIEVGDNGTAVTLTSCHISLEDSGMEDEERLDDMSSGVGDSWDSVKEAESEKRSRNGKRGNSACELPPLPKSLIGFNKLLCSDSGLLSDVEGNNNSSDGSRKPNDNLAVETQDTKEHATDKSLPSSPNGNTSIPPMLVAKSEAKSPSLSAKGNPQAVEAGSTLDAQIATLRKEMNGLRQLDLSLLSQLWVLNESIQEFRALIEDQENEDEDDEVEVEVGNELDEEGNSRVSSSIESVRLEGGADGTSKHLGTIPKVITTQPKVLRDSLATASKDQKPVPRMRSAPPPPPPAVLQSLSLERKPPAPSRPTXCYLSDFLAGVRMVMCKAIVSDVPASSASASLGGDGAPLGRDAQSCLGNQTGQVLQA", "length": 787, "header": "tr|A0ACA5YM07-1|A0ACA5YM07_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=CG31038 PE=3 SV=1 CANONICAL=A0ACA5YM07-1" }, "locus": {} }, { "isoform_ac": "Q9VAE7-1", "url": "https://www.uniprot.org/uniprotkb/A0ACA5YM07/entry#Q9VAE7-1", "sequence": { "sequence": "MATTAAGSAATTTNTMVVKRPGPPVPPRPKAAAQLANGAGAPPIIQKKPTFVSQLSAVGRTLVYKSPTVNLPKKQAQTQTPTTAVPTPPVKPLKLRKAPDVPTAKPRDSMTSVVTVNRHNSISVIGSTPQTTPRKDTRLSLGKVDFERAGLQPASQPLPRPRKIVQVPVATLDVEDIPVVAPSPSSNGLFRRSKTTLDGSQKDSASSPHNGGGFLSGRTVEIKNNLKNAAERLFSEIIINQSQKQAATDTTIITKHEALKQESDVLAIQSSGNCMRINVNGGQTSTMKSSISVGNTPQKKQAFHEMLISELAAMRNKSCSLEQLPTAKSPPPTTSTPKSVASRRRYNSIDDADTEDVDADNVEDADGDVDEEDTLTYAVNKSLKENIGKEGSSSRKRCPSGCSTDSSPYGTERSQRIRTSDWIEVGDNGTAVTLTSCHISLEDSGMEDEERLDDMSSGVGDSWDSVKEAESEKRSRNGKRGNSACELPPLPKSLIGFNKLLCSDSGLLSDVEGNNNSSDGSRKPNDNLAVETQDTKEHATDKSLPSSPNGNTSIPPMLVAKSEAKSPSLSAKGNPQAVEAGSTLDAQIATLRKEMNGLRQLDLSLLSQLWVLNESIQEFRALIEDQENEDEDDEVEVEVGNELDEEGNSRVSSSIESVRLEGGADGTSKHLGTIPKVITTQPKVLRDSLATASKDQKPVPRMRSAPPPPPPAVLQSLSLERKPPAPSRPT", "length": 730, "header": "tr|Q9VAE7-1|A0ACA5YM07_DROME Computationally mapped isoform of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=CG31038 PE=3 SV=2 CANONICAL=A0ACA5YM07-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 87, "start_aa": "Thr", "end_pos": 87, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr87", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHV6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHV6" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHV6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHV6" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHV6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHV6" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHV6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHV6" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHV6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHV6" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHV6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHV6" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHV6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHV6" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHV6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHV6" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHV6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHV6" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHV6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHV6" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KHV6", "url": "https://www.uniprot.org/uniprotkb/A0A0B4KHV6" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG31038", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG31038", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1QV06-1", "protein_name": "Leucine repeat adapter protein 25", "gene_name": "fam89b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNGFQCSPAECPAGSVCPVEGLPPLPKGLSGILNSSGGSWRDIEKVYSKRTRIQADISKSRVSDCLERSKPASLDAALAVLRKDMVGLRQLDMSLLCQLWSLYESIQEYKGAFQDISSSLCESSFNTENGYSEEEEEEDEDDHEAERGDTPLSFPQPAQNSRDQWIKDSFHIPI", "length": 174 }, "evidence": [ { "id": "RGD:1311544", "url": "https://alliancegenome.org/gene/RGD:1311544#orthology", "database": "AGR" }, { "id": "HGNC:16708", "url": "https://alliancegenome.org/gene/HGNC:16708#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091204-269", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091204-269#orthology", "database": "AGR" }, { "id": "MGI:106595", "url": "https://alliancegenome.org/gene/MGI:106595#orthology", "database": "AGR" }, { "id": "FB:FBgn0051038", "url": "https://alliancegenome.org/gene/FB:FBgn0051038#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB13A8F3-1", "protein_name": "Protein FAM89A", "gene_name": "fam89a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNDKVGNGAAGGVLACIEGLPPLPKSLSGLLNSSGGSWRDMERMYVKKTMIQDDLSRGRNNADNLLANKPANLDAALALLRKEMVGLRQQDMSLLCQLWSLHESIQEYKGSCQDLSAVSSADGPYGMENGYFDEDEEYYTESAVTPAETPDGNDTSPKNGTSKDSWIHDSFHITI", "length": 175 }, "evidence": [ { "id": "HGNC:25057", "url": "https://alliancegenome.org/gene/HGNC:25057#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-111019-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-111019-1#orthology", "database": "AGR" }, { "id": "RGD:1309879", "url": "https://alliancegenome.org/gene/RGD:1309879#orthology", "database": "AGR" }, { "id": "FB:FBgn0051038", "url": "https://alliancegenome.org/gene/FB:FBgn0051038#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q14BJ1-1", "protein_name": "Protein FAM89A", "gene_name": "Fam89a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGTGSAGMARGLRVDGLPPLPKSLSGLLHSAAGGAAGGWRHLERLYAQKSRIQDELNRGGAGGGGARAAGMRTKPPNLDAALALLRKEMVGLRQLDMSLLCQLYSLYESIQEYKGACQAASSLDCTYALENGFFDDEEDFQEQGSLQDGQHHGSPRDQSPLTHLSSSDWILESI", "length": 175 }, "evidence": [ { "id": "HGNC:25057", "url": "https://alliancegenome.org/gene/HGNC:25057#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-111019-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-111019-1#orthology", "database": "AGR" }, { "id": "RGD:1309879", "url": "https://alliancegenome.org/gene/RGD:1309879#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q566R4-1", "protein_name": "Leucine repeat adapter protein 25", "gene_name": "Fam89b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNGLPSTEAPGGAGCALAGLPPLPRGLSGLLNASGGSWRELERVYSQRSRIHDELSRAARAPDGPRHAAGSANLGSAAGPRRPVNLDSALAALRKEMVGLRQLDMSLLCQLWGLYESIQDYKHLCQDLSLCQDLSSSLHSDSSYPPDAGLSDDDEPPDASLPPDPPPLTVPQTHNARDQWLQDAFQISL", "length": 189 }, "evidence": [ { "id": "RGD:1311544", "url": "https://alliancegenome.org/gene/RGD:1311544#orthology", "database": "AGR" }, { "id": "HGNC:16708", "url": "https://alliancegenome.org/gene/HGNC:16708#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091204-269", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091204-269#orthology", "database": "AGR" }, { "id": "MGI:106595", "url": "https://alliancegenome.org/gene/MGI:106595#orthology", "database": "AGR" }, { "id": "FB:FBgn0051038", "url": "https://alliancegenome.org/gene/FB:FBgn0051038#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6Q0N2-1", "protein_name": "Protein FAM89A", "gene_name": "Fam89a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGAGSAGMARGLRVDGLPPLPKSLSGLLHSAAGGAAGGWRHLERLYAQKSRIQDELNRGGAGGGGARAAGMRTKPPNLDAALALLRKEMVGLRQLDMTLLCQLYGLYESIQEYKGACQAASSLDCNYALENGFFDDDEDFQEQGSLRDGQGRGSPGDPSLPLTHLSSSDWILESI", "length": 176 }, "evidence": [ { "id": "HGNC:25057", "url": "https://alliancegenome.org/gene/HGNC:25057#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-111019-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-111019-1#orthology", "database": "AGR" }, { "id": "RGD:1309879", "url": "https://alliancegenome.org/gene/RGD:1309879#orthology", "database": "AGR" }, { "id": "FB:FBgn0051038", "url": "https://alliancegenome.org/gene/FB:FBgn0051038#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8N5H3-3", "protein_name": "Leucine repeat adapter protein 25", "gene_name": "FAM89B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNGLPSAEAPGGAGCALAGLPPLPRGLSGLLNASGGSWRELERVYSQRSRIHDELSRAARAPDGPRHAAGAANAGPAAGPRRPVNLDSALAALRKEMVGLRQLDMSLLCQLWGLYESIQDYKHLCQDLSFCQDLSSSLHSDSSYPPDAGLSDDEEPPDASLPPDPPPLTVPQTHNARDQWLQDAFHISL", "length": 189 }, "evidence": [ { "id": "RGD:1311544", "url": "https://alliancegenome.org/gene/RGD:1311544#orthology", "database": "AGR" }, { "id": "HGNC:16708", "url": "https://alliancegenome.org/gene/HGNC:16708#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091204-269", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091204-269#orthology", "database": "AGR" }, { "id": "MGI:106595", "url": "https://alliancegenome.org/gene/MGI:106595#orthology", "database": "AGR" }, { "id": "FB:FBgn0051038", "url": "https://alliancegenome.org/gene/FB:FBgn0051038#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q96GI7-1", "protein_name": "Protein FAM89A", "gene_name": "FAM89A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSGARAAPGAAGNGAVRGLRVDGLPPLPKSLSGLLHSASGGGASGGWRHLERLYAQKSRIQDELSRGGPGGGGARAAALPAKPPNLDAALALLRKEMVGLRQLDMSLLCQLYSLYESIQEYKGACQAASSPDCTYALENGFFDEEEEYFQEQNSLHDRRDRGPPRDLSLPVSSLSSSDWILESI", "length": 184 }, "evidence": [ { "id": "HGNC:25057", "url": "https://alliancegenome.org/gene/HGNC:25057#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-111019-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-111019-1#orthology", "database": "AGR" }, { "id": "RGD:1309879", "url": "https://alliancegenome.org/gene/RGD:1309879#orthology", "database": "AGR" }, { "id": "FB:FBgn0051038", "url": "https://alliancegenome.org/gene/FB:FBgn0051038#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QUI1-1", "protein_name": "Leucine repeat adapter protein 25", "gene_name": "Fam89b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNGLPATEAPGGAGCALAGLPPLPRGLSGLLNASGGSWRELERVYSQRSRIHDELSRAARAPDGPRHAAGSANSGSAAGPRRPVNLDSALAALRKEMVGLRQLDMSLLCQLWGLYESIQDYKHLCQDLSLCQDLSSSLHSDSSYPPDAGLSDDEEPPDASLPPDPPPLTVPQTHNARDQWLQDAFQISL", "length": 189 }, "evidence": [ { "id": "RGD:1311544", "url": "https://alliancegenome.org/gene/RGD:1311544#orthology", "database": "AGR" }, { "id": "HGNC:16708", "url": "https://alliancegenome.org/gene/HGNC:16708#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091204-269", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091204-269#orthology", "database": "AGR" }, { "id": "MGI:106595", "url": "https://alliancegenome.org/gene/MGI:106595#orthology", "database": "AGR" }, { "id": "FB:FBgn0051038", "url": "https://alliancegenome.org/gene/FB:FBgn0051038#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VLJ5-1", "protein_name": "Lemming B, isoform A", "gene_name": "lmgB", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MMENSSNDAQPHLTGLPPLPKSLSAATAAPVAIGPHPRTASPASSVNALTVAAGELYLGPSTSSSAASRNRSYNGHGHSQRHGSLSSTQESLSDRESVHSRASSTHSAGAVHTPTNSSSSTGATSSTIDNQLAILRREMYGLRQLDLSLLSQLWALNESIQGFRVFLQEQDALSPPSRSRTPSDANSLSSDEEDDGSYAPVALPKMTDTAGAGSAGVVNSRAMASPAASGGLPTKLATGSTTSHASTSSTSGASGSSSAASSMGKHQQVQQQQQQQSQSANHYHQRPAPPPAPPAQHKAHPQLPRILQQRMRQAPPPPPPTRQKAGGGGGGGASTSSSNHSISSVTQPHPHSHQHPQHTHHSRPV", "length": 365 }, "evidence": [ { "id": "RGD:1311544", "url": "https://alliancegenome.org/gene/RGD:1311544#orthology", "database": "AGR" }, { "id": "HGNC:16708", "url": "https://alliancegenome.org/gene/HGNC:16708#orthology", "database": "AGR" }, { "id": "HGNC:25057", "url": "https://alliancegenome.org/gene/HGNC:25057#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091204-269", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091204-269#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-111019-1", "url": 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"end_pos": 615, "annotation": "n_glycosylation_sequon" }, { "start_pos": 779, "end_pos": 781, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 87 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 240, "end_pos": 242 }, { "start_pos": 316, "end_pos": 318 }, { "start_pos": 380, "end_pos": 382 }, { "start_pos": 428, "end_pos": 430 }, { "start_pos": 515, "end_pos": 517 }, { "start_pos": 516, "end_pos": 518 }, { "start_pos": 551, "end_pos": 553 }, { "start_pos": 613, "end_pos": 615 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Any dextro-looped transposition of the great arteries in which the cause of the disease is a mutation in the MED13L gene." }, { "id": "MONDO:0012128", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012128", "name": "DTGA", "description": "" }, { "id": "MONDO:0012128", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012128", "name": "DTGA1", "description": "" }, { "id": "MONDO:0012128", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012128", "name": "MED13L dextro-looped transposition of the great arteries", "description": "" }, { "id": "MONDO:0012128", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012128", "name": "dextro-looped transposition of the great arteries 1", "description": "" }, { "id": "MONDO:0012128", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012128", "name": "dextro-looped transposition of the great arteries caused by mutation in MED13L", "description": "" }, { "id": "MONDO:0012128", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012128", "name": "dextro-looped transposition of the great arteries type 1", "description": "" }, { "id": "MONDO:0012128", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012128", "name": "transposition of the great arteries, dextro-looped type 1", "description": "" }, { "id": "MONDO:0012128", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012128", "name": "transposition of the great arteries, dextro-looped 1", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "0060770", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060770" } ] }, { "disease_id": "DOID:0090005", "recommended_name": { "id": "DOID:0090005", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090005", "name": "Schwartz-Jampel syndrome 1", "description": "A syndrome characterized by neuromyotonia and chondrodysplasia that has_material_basis_in hypomorphic mutations in the HSPG2 gene on chromosome 1p36." }, "synonyms": [ { "id": "DOID:0090005", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090005", "name": "Aberfeld syndrome", "description": "" }, { "id": "DOID:0090005", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090005", "name": "Burton skeletal dysplasia", "description": "" }, { "id": "DOID:0090005", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090005", "name": "Burton syndrome", "description": "" }, { "id": "DOID:0090005", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090005", "name": "Catel-Hempel syndrome", "description": "" }, { "id": "DOID:0090005", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090005", "name": "Schwartz-Jampel syndrome type 1", "description": "" }, { "id": "DOID:0090005", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090005", "name": "Schwartz-Jampel-Aberfeld syndrome", "description": "" }, { "id": "DOID:0090005", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090005", "name": "Catel-Hempel type dysostosis enchondralis metaepiphysaria", "description": "" }, { "id": "DOID:0090005", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090005", "name": "myotonic chondrodystrophy", "description": "" }, { "id": "DOID:0090005", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090005", "name": "osteochondromuscular dystrophy", "description": "" }, { "id": "DOID:0090005", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090005", "name": "myotonic myopathy, dwarfism, chondrodystrophy, ocular and facial anomalies", "description": "" }, { "id": "MONDO:0100435", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0100435", "name": "Schwartz-Jampel syndrome type 1", "description": "" }, { "id": "MONDO:0100435", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0100435", "name": "SJA syndrome", "description": "" }, { "id": "MONDO:0100435", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0100435", "name": "SJS1", "description": "" }, { "id": "MONDO:0100435", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0100435", "name": "Schwartz-Jampel syndrome type 1", "description": "" }, { "id": "MONDO:0100435", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0100435", "name": "Schwartz-Jampel syndrome, type 1", "description": "" }, { "id": "MIM:255800", "resource": "MIM", "url": "https://www.omim.org/entry/255800", "name": "Schwartz-Jampel syndrome", "description": "Schwartz-Jampel syndrome" } ], "unlinked_id_list": [], "evidence": [ { "id": "0090005", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090005" } ] }, { "disease_id": "DOID:0090032", "recommended_name": { "id": "DOID:0090032", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090032", "name": "Silverman-Handmaker type dyssegmental dysplasia", "description": "An osteochondrodysplasia characterized by short-limbed dwarfism, anisospondyly, and neonatal lethality that has_material_basis_in autosomal recessive inheritance of homozygous or compound heterozygous mutation in the gene encoding perlecan (HSPG2) on chromosome 1p36." }, "synonyms": [ { "id": "MONDO:0009140", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009140", "name": "Silverman-Handmaker type dyssegmental dysplasia", "description": "Dyssegmental dysplasia, Silverman-Handmaker type is a rare, genetic, primary bone dysplasia, and lethal form of neonatal short-limbed dwarfism, characterized by anisospondyly, severe short stature and limb shortening, metaphyseal flaring and distinct dysmorphic features (i.e. flat facial appearance, abnormal ears, short neck, narrow thorax). Additional features may include other skeletal findings (e.g. joint contractures, bowed limbs, talipes equinovarus) and urogenital and cardiovascular abnormalities." }, { "id": "MONDO:0009140", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009140", "name": "Anisospondylic camptomicromelic dwarfism Silverman-Handmaker type", "description": "" }, { "id": "MONDO:0009140", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009140", "name": "DDSH", "description": "" }, { "id": "MONDO:0009140", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009140", "name": "dyssegmental dwarfism Silverman-Handmaker type", "description": "" }, { "id": "MONDO:0009140", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009140", "name": "dyssegmental dysplasia Silverman-Handmaker type", "description": "" }, { "id": "MONDO:0009140", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009140", "name": "dyssegmental dysplasia, Silverman-Handmaker type", "description": "" }, { "id": "MIM:224410", "resource": "MIM", "url": "https://www.omim.org/entry/224410", "name": "Dyssegmental dysplasia Silverman-Handmaker type", "description": "Dyssegmental dysplasia Silverman-Handmaker type" } ], "unlinked_id_list": [], "evidence": [ { "id": "0090032", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090032" } ] }, { "disease_id": "DOID:10763", "recommended_name": { "id": "DOID:10763", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries." }, "synonyms": [ { "id": "DOID:10763", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10763", "name": "HTN", "description": "" }, { "id": "DOID:10763", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10763", "name": "hyperpiesia", "description": "" }, { "id": "DOID:10763", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10763", "name": "vascular hypertensive disorder", "description": "" } ], "unlinked_id_list": [ "DOID:13731", "DOID:11130" ], "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ] }, { "disease_id": "DOID:13481", "recommended_name": { "id": "DOID:13481", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13481", "name": "thanatophoric dysplasia", "description": "An osteochondrodysplasia that results_in short arms and legs with excess folds of skin." }, "synonyms": [ { "id": "MONDO:0008546", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008546", "name": "thanatophoric dysplasia type 1", "description": "Thanatophoric dysplasia type 1 (TD1) is a form of TD characterized by short, bowed femurs, micromelia, narrow thorax, and brachydactyly." }, { "id": "MONDO:0008546", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008546", "name": "TD1", "description": "" }, { "id": "MONDO:0008546", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008546", "name": "thanatophoric dwarfism type 1", "description": "" }, { "id": "MONDO:0008546", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008546", "name": "thanatophoric dysplasia, type 1", "description": "" }, { "id": "MONDO:0008546", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008546", "name": "type 1 thanatophoric dysplasia", "description": "" }, { "id": "MONDO:0008546", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008546", "name": "PLSD San Diego type", "description": "" }, { "id": "MONDO:0008546", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008546", "name": 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "M9NFS1", "url": "https://www.uniprot.org/uniprotkb/M9NFS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "M9NFS1-1", "url": "https://www.uniprot.org/uniprotkb/M9NFS1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "M9NGK3", "url": "https://www.uniprot.org/uniprotkb/M9NGK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "M9NGK3-1", "url": "https://www.uniprot.org/uniprotkb/M9NGK3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "M9NGL3", "url": "https://www.uniprot.org/uniprotkb/M9NGL3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "M9NGL3-1", "url": "https://www.uniprot.org/uniprotkb/M9NGL3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q7KVZ0", "url": "https://www.uniprot.org/uniprotkb/Q7KVZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q7KVZ0-1", "url": "https://www.uniprot.org/uniprotkb/Q7KVZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q8IRV7", "url": "https://www.uniprot.org/uniprotkb/Q8IRV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q8IRV7-1", "url": "https://www.uniprot.org/uniprotkb/Q8IRV7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q8IRV8", "url": "https://www.uniprot.org/uniprotkb/Q8IRV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q8IRV8-1", "url": "https://www.uniprot.org/uniprotkb/Q8IRV8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q8IRV9", "url": "https://www.uniprot.org/uniprotkb/Q8IRV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q8IRV9-1", "url": "https://www.uniprot.org/uniprotkb/Q8IRV9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W4Y3", "url": "https://www.uniprot.org/uniprotkb/Q9W4Y3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W4Y3-1", "url": "https://www.uniprot.org/uniprotkb/Q9W4Y3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W4Y4", "url": "https://www.uniprot.org/uniprotkb/Q9W4Y4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W4Y4-1", "url": "https://www.uniprot.org/uniprotkb/Q9W4Y4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "X2JAC7", "url": "https://www.uniprot.org/uniprotkb/X2JAC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "X2JAC7-1", "url": "https://www.uniprot.org/uniprotkb/X2JAC7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "X2JCE8", "url": "https://www.uniprot.org/uniprotkb/X2JCE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "X2JCE8-1", "url": "https://www.uniprot.org/uniprotkb/X2JCE8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "X2JDK9", "url": "https://www.uniprot.org/uniprotkb/X2JDK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "X2JDK9-1", "url": "https://www.uniprot.org/uniprotkb/X2JDK9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "X2JE09", "url": "https://www.uniprot.org/uniprotkb/X2JE09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "X2JE09-1", "url": "https://www.uniprot.org/uniprotkb/X2JE09-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMGSPGSQASAIATSVGIRSGRRGQAGGSLLLRLLAVTFVLAACHAPLLTNAKQISNLGDDQDFMLADDESLQGINDSEWQLMGDDIDDGLLDDVDETLKPMETKSEEEDLPTGNWFSQSVHRVRRSINRLFGSDDNQERGRRQQRERSQRNRDAINRQKELRRRQKEDHNRWKQMRMERQLEKQRLVKRTNHVVFNRATDPRKRASDLYDENEASGYHEEDTTLYRTYFVVNEPYDNEYRDRESVQFQNLQKLLDDDLRNFFHSNYEGNDDEEQEIRSTLERVEPTNDNFKIRVQLRIELPTSVNDFGSKLQQQLNVYNRIENLSAATDGVFSFTESSVTEESVRHLDVGFVEPHITLFHEQNTGYDDFDRKPTTETQDIEEEAIDVTLPQEEVEGSGSDDSSCRGDATFTCPRSGKTICDEMRCDREIQCPDGEDEEYCNYPNVCTEDQFKCDDKCLELKKRCDGSIDCLDQTDEAGCINAPEPEPEPEPEPEPEPESEPEAEPEPEPEPEPESEPEQEPEPQVPEANECQANEFRCNNGDCIDARKRCNNVSDCSEGEDENEECPAACSGMEYQCRDGTRCISVSQQCDGHSDCSDGDDEEHCDGSGYDSEECRFDEFHCGTGECIPMRQVCDNIYDCNDYSDEVNCVEGEEEDRVGIPIGHQPWRPASKHDDWLHEMDTSEYQVYQPSNVYEKANSQNPCASNQFRCTTSNVCIPLHLRCDGFYHCNDMSDEKSCEQYQRHTTTRRPLTLATPTSRITTQGPGLLERRNTTTATEASRWPWATKTTTIATTTSNPITTVGVANSPPQTCLENIEFACHNRDCISIESVCDGIPDCGRNEDEDDALCKCSGDKYKCQRGGGCIPKSQVCDGKPQCHDRSDESACHLHGRLNKTRLGVKCLESQYQCGDGSCISGYKRCNGIHDCADASDEYNCIYDYEDTYDTDPNNNPLNECDILEFECDYSQCLPLEKKCDGYADCEDMSDELECQSYTDHCLESEFECDSYCLPRDQLCNGIPNCQDGSDERNCTFCREDAYLCNTGECVADNQRCNGIADCADGSDERHCARIYCPPNKLACNGTCVSRRIKCDGIRDCLDGYDEMYCPETNNHYPTQNVNVIRPKLGPNPIPKSCRPHEWQCANLECIDSSLQCNEIKDCSDGSDEELSVCFGTATTRLKPSDCSPEQFYCDESCYNRSVRCNGHVDCSDGSDEVGCSLPCPQHQCPSGRCYTESERCDRHRHCEDGSDEANCCYANQFRCNNGDCVSGSAPCNGYSECSDHSDELNCGGTQECLPNQFRCNSGQCVSSSVRCNGRTDCQDSSDEQNCAADSNDRRPNQLNLKTYPDSQIIKESREVIFRCRDEGPARAKVKWSRPGGRPLPPGFTDRNGRLEIPNIRVEDAGTYVCEAVGYASYIPGQQVTVNLNVERYNDVGSRPESACTEYQATCMNGECIDKSSICDGNPDCSDASDEQSCSLGLKCQPNQFMCSNSKCVDRTWRCDGENDCGDNSDETSCDPEPSGAPCRYNEFQCRSGHCIPKSFQCDNVPDCTDGTDEVGCMAPLPIRPPPQSVSLLEYEVLELTCVATGTPTPTIVWRLNWGHVPDKCESKSYGGTGTLRCPDMRPQDSGAYSCEIINTRGTHFVNPDTIVTVRPVRTDVCEAGFFNMLARKAEECVQCFCFGVAKACDSANLFTYAIHPPILSHRVVSVELSPLRQIVINEAAPGQDLLTLLHGVQFRATNVHFSGRETPYLALPADYMGNQLKSYGGNLRYEVNYRGSGRPVNGPDVIITGNRFTLTYRVRTQPGQNNRVSIPFVPGGWQKPDGRKASREEIMMILANVDNILIRLGYLDSTAREVDLINIALDSAGTADKGLGSASLVEKCQCPPGYVGDSCESCASGYVRQPGGPWLGHCVPFIPDSCPSGTYGDPRRGVPCKECPCPLTGSNNFASGCQQSPDGDVVCRCNEGYTGRRCEQCAAGYQGNPLAAGGICRRIPDTSCNVDGTYSVHSNGTCQCKDSVIGEQCDTCKSKSFHLNSFTYTGCIECFCSGVGLDCDSSTWYRDQVTSTFGRSRVDHGFVLVTNYMQPTPDTVPVSMAAEPNALSFIGSADQSGNTLYWSLPAAFLGNKLSSYGGKLTYTLSYSPLPNGIMSRNSAPDVVIKSGEDLRLIHYRKSQVVPSVANTYSVEIKESAWQRGDEVVANREHVLMALSDITAIYIKATYTTSTKEASLRQVTLDVATPTNLGTPRAVEVEQCRCPEGYLGLSCEQCAPGYARDPEGGIYLGLCRPCECNGHSKYCNSDTGDCEECSDNTEGPSCERCAAGYVGDATRGTIYDCQPDEGYPIPSPPAPGNQTLECTAYCQIEGIYDCRGNECLCKRNVIGDQCDQCRPGTYGLSAQNQDGCKECYCSGLASQCRSAALYRQLIPVDFILNAPLITDESGAVQDTENLIPDISRNMYTYTHTSYLPKYWSLRGSVLGNQLFSYGGRLSYSLIVESYGNYERGHDIVLIGNGLKLIWSRPDGNENQEEYNVRLHEDEQWTRQDRESARPASRSDFMTVLSDLQHILIRATPRVPTQSTSIGNVILESAVTTRTPGATHASDIELCQCPSGYVGTSCESCAPLHYRDASGSCSLCPCDVSNTESCDLVSGGYVECRCKARWKGDRCREIDTNDPTDIGTEDPVLTQIIVSIQKPEITIVPVGGSMTLSCSGRMRWSNSPVIVNWYKENSRLPENVEVQGGNLYLYDLQVSDSGVYICQAVNNETASVFKDTVSITITRYAQEMLARYEKDQLSPAEIVNLPSHVTFEEYVNNEIICEVLGNPAPRVTWARVDGHADAQSTRTYDNRLIFDSPRKSDEGRYRCQAENDQNRDEKYVIVYVQSNPPQPPPQQDRLYITPEEINGLAGESFQLNCQFTSVASLRYDWSHNGRSLSSSPARNVEIRGNTLEVRDASESDSGVYTCVAYDVRTRRNFTESARVNIDRREEQPFGNKPIIESLEQNILIIQGEDYSITCEASGSPYPSIKWAKVHDFMPENVHISGNVLTIYGARFENRGVYSCVAENDHGSDLSSTSIDIEPRERPSVKIVSAPLQTFSVGAPASLYCTVEGIPDPTVEWVRVDGQPLSPRHKIQSPGYMVIDDIQLEDSGDYECRAKNIVGEATGVATITVQEPTLVQIIPDNRDLRLTEGDELSLTCVGSGVPNPEVEWVNEMALKRDLYSPPSNTAILKIYRVTKADAGIYTCHGKNEAGSDEAHVRVEVQERRGDIGGVDDDSDRDPINYNPPQQQNPGIHQPGSNQLLATDIGDNVTLTCDMFQPLNTRWERVDGAPLPRNAYTIKNRLEIVRVEQQNLGQYRCNGIGRDGNVKTYFVKELVLMPLPRIRFYPNIPLTVEAGQNLDVHCQVENVRPEDVHWSTDNNRPLPSSVRIVGSVLRFVSITQAAAGEYRCSAFNQYGNRSQIARVAVKKPADFHQVPQSQLQRHREGENIQLQCTVTDQYGVRAQDNVEFNWFRDDRRPLPNNARTDSQILVLTNLRPEDAGRYICNSYDVDRGQQLPEVSIDLQVLRAPQYPYNRFKGGVSLKDTPCMVLYICAAATPPPNSPIYLPPQLPAKSRDYSLKLDDQSSNLRAGESTDVECYSSDDTYTDVVWERSDGAPLSNNVRQVGNRLVISNVSPSDAGNYVCKCKTDEGDLYTTSYKLEVEDQPHELKSSKIVYAKVGANADLQCGADESRQPTYRWSRQYGQLQAGRSLMNEKLSLDSVQANDAGTYICTAQYADGETADFPNILVVTGAIPQFRQEPRSYMSFPTLPNSSFKFNFELTFRPENGDGLLLFNGQTRGSGDYIALSLKDRYAEFRFDFGGKPMLVRAEEPLALNEWHTVRVSRFKRDGYIQVDEQHPVAFPTLQQIPQLDLIEDLYIGGVPNWELLPADAVSQQVGFVGCISRLTLQGRTVELIREAKYKEGITDCRPCAQGPCQNKGVCLESQTEQAYTCICQPGWTGRDCAIEGTQCTPGVCGAGRCENTENDMECLCPLNRSGDRCQYNEILNEHSLNFKGNSFAAYGTPKVTKVNITLSVRPASLEDSVILYTAESTLPSGDYLALVLRGGHAELLINTAARLDPVVVRSAEPLPLNRWTRIEIRRRLGEGILRVGDGPERKAKAPGSDRILSLKTHLYVGGYDRSTVKVNRDVNITKGFDGCISRLYNFQKPVNLLADIKDAANIQSCGETNMIGGDEDSDNEPPVPPPTPDVHENELQPYAMAPCASDPCENGGSCSEQEDVAVCSCPFGFSGKHCQEHLQLGFNASFRGDGYVELNRSHFQPALEQSYTSMGIVFTTNKPNGLLFWWGQEAGEEYTGQDFIAAAVVDGYVEYSMRLDGEEAVIRNSDIRVDNGERHIVIAKRDENTAILEVDRMLHSGETRPTSKKSMKLPGNVFVGGAPDLEVFTGFRYKHNLNGCIVVVEGETVGQINLSSAAVNGVNANVCPANDDPLGGTEPPVV", "length": 4489, "header": "tr|A0ACD4DAU3-1|A0ACD4DAU3_DROME Isoform 1 of Terribly reduced optic lobes, isoform BD OS=Drosophila melanogaster OX=7227 GN=trol PE=1 SV=1 CANONICAL=A0ACD4DAU3-1" }, "isoforms": [ { "isoform_ac": "A0A023GRW4-1", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3/entry#A0A023GRW4-1", "sequence": { "sequence": "MMGSPGSQASAIATSVGIRSGRRGQAGGSLLLRLLAVTFVLAACHAPLLTNAKQISNLGDDQDFMLADDESLQGINDSEWQLMGDDIDDGLLDDVDETLKPMETKSEEEDLPTGNWFSQSVHRVRRSINRLFGSDDNQERGRRQQRERSQRNRDAINRQKELRRRQKEDHNRWKQMRMERQLEKQRLVKRTNHVVFNRATDPRKRASDLYDENEASGYHEEDTTLYRTYFVVNEPYDNEYRDRESVQFQNLQKLLDDDLRNFFHSNYEGNDDEEQEIRSTLERVEIELPTSVNDFGSKLQQQLNVYNRIENLSAATDGVFSFTESSVTEESVRHLDVGFVEPHITLFHEQNTGYDDFDRKPTTETQDIEEEAIDVTLPQEEVEGSGSDDSSCRGDATFTCPRSGKTICDEMRCDREIQCPDGEDEEYCNYPNVCTEDQFKCDDKCLELKKRCDGSIDCLDQTDEAGCINAPEPEPEPEPEPEPEPESEPEAEPEPEPEPEPESEPEQEPEPQVPEANECQANEFRCNNGDCIDARKRCNNVSDCSEGEDENEECLEGEEEDRVGIPIGHQPWRPASKHDDWLHEMDTSEYQVYQPSNVYEKANSQNPCASNQFRCTTSNVCIPLHLRCDGFYHCNDMSDEKSCEQYQRHTTTRRPLTLATPTSRITTQGPGLLERRNTTTATEASRWPWATKTTTIATTTSNPITTVGVATTTRLKPSDCSPEQFYCDESCYNRSVRCNGHVDCSDGSDEVGCSLPCPQHQCPSGRCYTESERCDRHRHCEDGSDEANCCYANQFRCNNGDCVSGSAPCNGYSECSDHSDELNCGGTQECLPNQFRCNSGQCVSSSVRCNGRTDCQDSSDEQNCAADSNDRRPNQLNLKTYPDSQIIKESREVIFRCRDEGPARAKVKWSRPGGRPLPPGFTDRNGRLEIPNIRVEDAGTYVCEAVGYASYIPGQQVTVNLNVERYNDVGSRPESACTEYQATCMNGECIDKSSICDGNPDCSDASDEQSCSLGLKCQPNQFMCSNSKCVDRTWRCDGENDCGDNSDETSCDPEPSGAPCRYNEFQCRSGHCIPKSFQCDNVPDCTDGTDEVGCMAPLPIRPPPQSVSLLEYEVLELTCVATGTPTPTIVWRLNWGHVPDKCESKSYGGTGTLRCPDMRPQDSGAYSCEIINTRGTHFVNPDTIVTVRPVRTDVCEAGFFNMLARKAEECVQCFCFGVAKACDSANLFTYAIHPPILSHRVVSVELSPLRQIVINEAAPGQDLLTLLHGVQFRATNVHFSGRETPYLALPADYMGNQLKSYGGNLRYEVNYRGSGRPVNGPDVIITGNRFTLTYRVRTQPGQNNRVSIPFVPGGWQKPDGRKASREEIMMILANVDNILIRLGYLDSTAREVDLINIALDSAGTADKGLGSASLVEKCQCPPGYVGDSCESCASGYVRQPGGPWLGHCVPFIPDSCPSGTYGDPRRGVPCKECPCPLTGSNNFASGCQQSPDGDVVCRCNEGYTGRRCEQCAAGYQGNPLAAGGICRRIPDTSCNVDGTYSVHSNGTCQCKDSVIGEQCDTCKSKSFHLNSFTYTGCIECFCSGVGLDCDSSTWYRDQVTSTFGRSRVDHGFVLVTNYMQPTPDTVPVSMAAEPNALSFIGSADQSGNTLYWSLPAAFLGNKLSSYGGKLTYTLSYSPLPNGIMSRNSAPDVVIKSGEDLRLIHYRKSQVVPSVANTYSVEIKESAWQRGDEVVANREHVLMALSDITAIYIKATYTTSTKEASLRQVTLDVATPTNLGTPRAVEVEQCRCPEGYLGLSCEQCAPGYARDPEGGIYLGLCRPCECNGHSKYCNSDTGDCEECSDNTEGPSCERCAAGYVGDATRGTIYDCQPDEGYPIPSPPAPGNQTLECTAYCQIEGIYDCRGNECLCKRNVIGDQCDQCRPGTYGLSAQNQDGCKECYCSGLASQCRSAALYRQLIPVDFILNAPLITDESGAVQDTENLIPDISRNMYTYTHTSYLPKYWSLRGSVLGNQLFSYGGRLSYSLIVESYGNYERGHDIVLIGNGLKLIWSRPDGNENQEEYNVRLHEDEQWTRQDRESARPASRSDFMTVLSDLQHILIRATPRVPTQSTSIGNVILESAVTTRTPGATHASDIELCQCPSGYVGTSCESCAPLHYRDASGSCSLCPCDVSNTESCDLVSGGYVECRCKARWKGDRCREIDTNDPTDIGTEDPVLTQIIVSIQKPEITIVPVGGSMTLSCSGRMRWSNSPVIVNWYKENSRLPENVEVQGGNLYLYDLQVSDSGVYICQAVNNETASVFKDTVSITITKKDQLSPAEIVNLPSHVTFEEYVNNEIICEVLGNPAPRVTWARVDGHADAQSTRTYDNRLIFDSPRKSDEGRYRCQAENDQNRDEKYVIVYVQSNPPQPPPQQDRLYITPEEINGLAGESFQLNCQFTSVASLRYDWSHNGRSLSSSPARNVEIRGNTLEVRDASESDSGVYTCVAYDVRTRRNFTESARVNIDRREEQPFGNKPIIESLEQNILIIQGEDYSITCEASGSPYPSIKWAKVHDFMPENVHISGNVLTIYGARFENRGVYSCVAENDHGSDLSSTSIDIEPRERPSVKIVSAPLQTFSVGAPASLYCTVEGIPDPTVEWVRVDGQPLSPRHKIQSPGYMVIDDIQLEDSGDYECRAKNIVGEATGVATITVQEPTLVQIIPDNRDLRLTEGDELSLTCVGSGVPNPEVEWVNEMALKRDLYSPPSNTAILKIYRVTKADAGIYTCHGKNEAGSDEAHVRVEVQERRGDIGGVDDDSDRDPINYNPPQQQNPGIHQPGSNQLLATDIGDNVTLTCDMFQPLNTRWERVDGAPLPRNAYTIKNRLEIVRVEQQNLGQYRCNGIGRDGNVKTYFVKELVLMPLPRIRFYPNIPLTVEAGQNLDVHCQVENVRPEDVHWSTDNNRPLPSSVRIVGSVLRFVSITQAAAGEYRCSAFNQYGNRSQIARVAVKKPADFHQVPQSQLQRHREGENIQLQCTVTDQYGVRAQDNVEFNWFRDDRRPLPNNARTDSQILVLTNLRPEDAGRYICNSYDVDRGQQLPEVSIDLQVLTATPPPNSPIYLPPQLPAKSRDYSLKLDDQSSNLRAGESTDVECYSSDDTYTDVVWERSDGAPLSNNVRQVGNRLVISNVSPSDAGNYVCKCKTDEGDLYTTSYKLEVEDQPHELKSSKIVYAKVGANADLQCGADESRQPTYRWSRQYGQLQAGRSLMNEKLSLDSVQANDAGTYICTAQYADGETADFPNILVVTGAIPQFRQEPRSYMSFPTLPNSSFKFNFELTFRPENGDGLLLFNGQTRGSGDYIALSLKDRYAEFRFDFGGKPMLVRAEEPLALNEWHTVRVSRFKRDGYIQVDEQHPVAFPTLQQIPQLDLIEDLYIGGVPNWELLPADAVSQQVGFVGCISRLTLQGRTVELIREAKYKEGITDCRPCAQGPCQNKGVCLESQTEQAYTCICQPGWTGRDCAIEGTQCTPGVCGAGRCENTENDMECLCPLNRSGDRCQYNEILNEHSLNFKGNSFAAYGTPKVTKVNITLSVRPASLEDSVILYTAESTLPSGDYLALVLRGGHAELLINTAARLDPVVVRSAEPLPLNRWTRIEIRRRLGEGILRVGDGPERKAKAPGSDRILSLKTHLYVGGYDRSTVKVNRDVNITKGFDGCISRLYNFQKPVNLLADIKDAANIQSCGETNMIGGDEDSDNEPPVPPPTPDVHENELQPYAMAPCASDPCENGGSCSEQEDVAVCSCPFGFSGKHCQEHLQLGFNASFRGDGYVELNRSHFQPALEQSYTSMGIVFTTNKPNGLLFWWGQEAGEEYTGQDFIAAAVVDGYVEYSMRLDGEEAVIRNSDIRVDNGERHIVIAKRDENTAILEVDRMLHSGETRPTSKKSMKLPGNVFVGGAPDLEVFTGFRYKHNLNGCIVVVEGETVGQINLSSAAVNGVNANVCPANDDPLGGTEPPVV", "length": 3989, "header": "tr|A0A023GRW4-1|A0ACD4DAU3_DROME Computationally mapped isoform of Terribly reduced optic lobes, isoform BD OS=Drosophila melanogaster OX=7227 GN=trol PE=1 SV=1 CANONICAL=A0ACD4DAU3-1" }, "locus": {} }, { "isoform_ac": "A0A6H2EG25-1", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3/entry#A0A6H2EG25-1", "sequence": { "sequence": "MMGSPGSQASAIATSVGIRSGRRGQAGGSLLLRLLAVTFVLAACHAPLLTNAKQISNLGDDQDFMLADDESLQGINDSEWQLMGDDIDDGLLDDVDETLKPMETKSEEEDLPTGNWFSQSVHRVRRSINRLFGSDDNQERGRRQQRERSQRNRDAINRQKELRRRQKEDHNRWKQMRMERQLEKQRLVKRTNHVVFNRATDPRKRASDLYDENEASGYHEEDTTLYRTYFVVNEPYDNEYRDRESVQFQNLQKLLDDDLRNFFHSNYEGNDDEEQEIRSTLERVEPTNDNFKIRVQLRIELPTSVNDFGSKLQQQLNVYNRIENLSAATDGVFSFTESSDIEEEAIDVTLPQEEVEGSGSDDSSCRGDATFTCPRSGKTICDEMRCDREIQCPDGEDEEYCNYPNVCTEDQFKCDDKCLELKKRCDGSIDCLDQTDEAGCINAPEPEPEPEPEPEPEPESEPEAEPEPEPEPEPESEPEQEPEPQVPEANECQANEFRCNNGDCIDARKRCNNVSDCSEGEDENEECRCYANQFRCNNGDCVSGSAPCNGYSECSDHSDELNCGGTQECLPNQFRCNSGQCVSSSVRCNGRTDCQDSSDEQNCAADSNDRRPNQLNLKTYPDSQIIKESREVIFRCRDEGPARAKVKWSRPGGRPLPPGFTDRNGRLEIPNIRVEDAGTYVCEAVGYASYIPGQQVTVNLNVERSWGENKYEEIRSNRIRYGTVPHIDLEFFGLDNDVGSRPESACTEYQATCMNGECIDKSSICDGNPDCSDASDEQSCSLGLKCQPNQFMCSNSKCVDRTWRCDGENDCGDNSDETSCDPEPSGAPCRYNEFQCRSGHCIPKSFQCDNVPDCTDGTDEVGCMAPLPIRPPPQSVSLLEYEVLELTCVATGTPTPTIVWRLNWGHVPDKCESKSYGGTGTLRCPDMRPQDSGAYSCEIINTRGTHFVNPDTIVTVRPVRTDVCEAGFFNMLARKAEECVQCFCFGVAKACDSANLFTYAIHPPILSHRVVSVELSPLRQIVINEAAPGQDLLTLLHGVQFRATNVHFSGRETPYLALPADYMGNQLKSYGGNLRYEVNYRGSGRPVNGPDVIITGNRFTLTYRVRTQPGQNNRVSIPFVPGGWQKPDGRKASREEIMMILANVDNILIRLGYLDSTAREVDLINIALDSAGTADKGLGSASLVEKCQCPPGYVGDSCESCASGYVRQPGGPWLGHCVPFIPDSCPSGTYGDPRRGVPCKECPCPLTGSNNFASGCQQSPDGDVVCRCNEGYTGRRCEQCAAGYQGNPLAAGGICRRIPDTSCNVDGTYSVHSNGTCQCKDSVIGEQCDTCKSKSFHLNSFTYTGCIECFCSGVGLDCDSSTWYRDQVTSTFGRSRVDHGFVLVTNYMQPTPDTVPVSMAAEPNALSFIGSADQSGNTLYWSLPAAFLGNKLSSYGGKLTYTLSYSPLPNGIMSRNSAPDVVIKSGEDLRLIHYRKSQVVPSVANTYSVEIKESAWQRGDEVVANREHVLMALSDITAIYIKATYTTSTKEASLRQVTLDVATPTNLGTPRAVEVEQCRCPEGYLGLSCEQCAPGYARDPEGGIYLGLCRPCECNGHSKYCNSDTGDCEECSDNTEGPSCERCAAGYVGDATRGTIYDCQPDEGYPIPSPPAPGNQTLECTAYCQIEGIYDCRGNECLCKRNVIGDQCDQCRPGTYGLSAQNQDGCKECYCSGLASQCRSAALYRQLIPVDFILNAPLITDESGAVQDTENLIPDISRNMYTYTHTSYLPKYWSLRGSVLGNQLFSYGGRLSYSLIVESYGNYERGHDIVLIGNGLKLIWSRPDGNENQEEYNVRLHEDEQWTRQDRESARPASRSDFMTVLSDLQHILIRATPRVPTQSTSIGNVILESAVTTRTPGATHASDIELCQCPSGYVGTSCESCAPLHYRDASGSCSLCPCDVSNTESCDLVSGGYVECRCKARWKGDRCREIDTNDPTDIGTEDPVLTQIIVSIQKPEITIVPVGGSMTLSCSGRMRWSNSPVIVNWYKENSRLPENVEVQGGNLYLYDLQVSDSGVYICQAVNNETASVFKDTVSITITKKDQLSPAEIVNLPSHVTFEEYVNNEIICEVLGNPAPRVTWARVDGHADAQSTRTYDNRLIFDSPRKSDEGRYRCQAENDQNRDEKYVIVYVQSNPPQPPPQQDRLYITPEEINGLAGESFQLNCQFTSVASLRYDWSHNGRSLSSSPARNVEIRGNTLEVRDASESDSGVYTCVAYDVRTRRNFTESARVNIDRREEQPFGNKPIIESLEQNILIIQGEDYSITCEASGSPYPSIKWAKVHDFMPENVHISGNVLTIYGARFENRGVYSCVAENDHGSDLSSTSIDIEPRERPSVKIVSAPLQTFSVGAPASLYCTVEGIPDPTVEWVRVDGQPLSPRHKIQSPGYMVIDDIQLEDSGDYECRAKNIVGEATGVATITVQEPTLVQIIPDNRDLRLTEGDELSLTCVGSGVPNPEVEWVNEMALKRDLYSPPSNTAILKIYRVTKADAGIYTCHGKNEAGSDEAHVRVEVQERRGDIGGVDDDSDRDPINYNPPQQQNPGIHQPGSNQLLATDIGDNVTLTCDMFQPLNTRWERVDGAPLPRNAYTIKNRLEIVRVEQQNLGQYRCNGIGRDGNVKTYFVKELVLMPLPRIRFYPNIPLTVEAGQNLDVHCQVENVRPEDVHWSTDNNRPLPSSVRIVGSVLRFVSITQAAAGEYRCSAFNQYGNRSQIARVAVKKPADFHQVPQSQLQRHREGENIQLQCTVTDQYGVRAQDNVEFNWFRDDRRPLPNNARTDSQILVLTNLRPEDAGRYICNSYDVDRGQQLPEVSIDLQVLRAPQYPYNRFKGGVSLKDTPCMVLYICADFKSSKLSSAKPIISGPATTRAPAISYVCQPNDFKCVSHPHTCVRANMVCDGIYDCTDHSDEFNCIAGKGSGKSESNSGSGSFKRWKKSPEQGRRSLAKAVKNRKLRKRSFAATPPPNSPIYLPPQLPAKSRDYSLKLDDQSSNLRAGESTDVECYSSDDTYTDVVWERSDGAPLSNNVRQVGNRLVISNVSPSDAGNYVCKCKTDEGDLYTTSYKLEVEDQPHELKSSKIVYAKVGANADLQCGADESRQPTYRWSRQYGQLQAGRSLMNEKLSLDSVQANDAGTYICTAQYADGETADFPNILVVTGAIPQFRQEPRSYMSFPTLPNSSFKFNFELTFRPENGDGLLLFNGQTRGSGDYIALSLKDRYAEFRFDFGGKPMLVRAEEPLALNEWHTVRVSRFKRDGYIQVDEQHPVAFPTLQQIPQLDLIEDLYIGGVPNWELLPADAVSQQVGFVGCISRLTLQGRTVELIREAKYKEGITDCRPCAQGPCQNKGVCLESQTEQAYTCICQPGWTGRDCAIEGTQCTPGVCGAGRCENTENDMECLCPLNRSGDRCQYNEILNEHSLNFKGNSFAAYGTPKVTKVNITLSVRPASLEDSVILYTAESTLPSGDYLALVLRGGHAELLINTAARLDPVVVRSAEPLPLNRWTRIEIRRRLGEGILRVGDGPERKAKAPGSDRILSLKTHLYVGGYDRSTVKVNRDVNITKGFDGCISRLYNFQKPVNLLADIKDAANIQSCGETNMIGGDEDSDNEPPVPPPTPDVHENELQPYAMAPCASDPCENGGSCSEQEDVAVCSCPFGFSGKHCQEHLQLGFNASFRGDGYVELNRSHFQPALEQSYTSMGIVFTTNKPNGLLFWWGQEAGEEYTGQDFIAAAVVDGYVEYSMRLDGEEAVIRNSDIRVDNGERHIVIAKRDENTAILEVDRMLHSGETRPTSKKSMKLPGNVFVGGAPDLEVFTGFRYKHNLNGCIVVVEGETVGQINLSSAAVNGVNANVCPALWSPSSLVHQEIDTNVVMDHHVIGKDLSFFDELDQPPPVHILYPRPKINEFPTNKAPRVVLPLSLSLSILIFSYRLSVISLCLLPAPS", "length": 3972, "header": "tr|A0A6H2EG25-1|A0ACD4DAU3_DROME Computationally mapped isoform of Terribly reduced optic lobes, isoform BD OS=Drosophila melanogaster OX=7227 GN=trol PE=1 SV=1 CANONICAL=A0ACD4DAU3-1" }, "locus": {} }, { "isoform_ac": "A0ACD4DAU3-1", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3/entry#A0ACD4DAU3-1", "sequence": { "sequence": "MMGSPGSQASAIATSVGIRSGRRGQAGGSLLLRLLAVTFVLAACHAPLLTNAKQISNLGDDQDFMLADDESLQGINDSEWQLMGDDIDDGLLDDVDETLKPMETKSEEEDLPTGNWFSQSVHRVRRSINRLFGSDDNQERGRRQQRERSQRNRDAINRQKELRRRQKEDHNRWKQMRMERQLEKQRLVKRTNHVVFNRATDPRKRASDLYDENEASGYHEEDTTLYRTYFVVNEPYDNEYRDRESVQFQNLQKLLDDDLRNFFHSNYEGNDDEEQEIRSTLERVEPTNDNFKIRVQLRIELPTSVNDFGSKLQQQLNVYNRIENLSAATDGVFSFTESSVTEESVRHLDVGFVEPHITLFHEQNTGYDDFDRKPTTETQDIEEEAIDVTLPQEEVEGSGSDDSSCRGDATFTCPRSGKTICDEMRCDREIQCPDGEDEEYCNYPNVCTEDQFKCDDKCLELKKRCDGSIDCLDQTDEAGCINAPEPEPEPEPEPEPEPESEPEAEPEPEPEPEPESEPEQEPEPQVPEANECQANEFRCNNGDCIDARKRCNNVSDCSEGEDENEECPAACSGMEYQCRDGTRCISVSQQCDGHSDCSDGDDEEHCDGSGYDSEECRFDEFHCGTGECIPMRQVCDNIYDCNDYSDEVNCVEGEEEDRVGIPIGHQPWRPASKHDDWLHEMDTSEYQVYQPSNVYEKANSQNPCASNQFRCTTSNVCIPLHLRCDGFYHCNDMSDEKSCEQYQRHTTTRRPLTLATPTSRITTQGPGLLERRNTTTATEASRWPWATKTTTIATTTSNPITTVGVANSPPQTCLENIEFACHNRDCISIESVCDGIPDCGRNEDEDDALCKCSGDKYKCQRGGGCIPKSQVCDGKPQCHDRSDESACHLHGRLNKTRLGVKCLESQYQCGDGSCISGYKRCNGIHDCADASDEYNCIYDYEDTYDTDPNNNPLNECDILEFECDYSQCLPLEKKCDGYADCEDMSDELECQSYTDHCLESEFECDSYCLPRDQLCNGIPNCQDGSDERNCTFCREDAYLCNTGECVADNQRCNGIADCADGSDERHCARIYCPPNKLACNGTCVSRRIKCDGIRDCLDGYDEMYCPETNNHYPTQNVNVIRPKLGPNPIPKSCRPHEWQCANLECIDSSLQCNEIKDCSDGSDEELSVCFGTATTRLKPSDCSPEQFYCDESCYNRSVRCNGHVDCSDGSDEVGCSLPCPQHQCPSGRCYTESERCDRHRHCEDGSDEANCCYANQFRCNNGDCVSGSAPCNGYSECSDHSDELNCGGTQECLPNQFRCNSGQCVSSSVRCNGRTDCQDSSDEQNCAADSNDRRPNQLNLKTYPDSQIIKESREVIFRCRDEGPARAKVKWSRPGGRPLPPGFTDRNGRLEIPNIRVEDAGTYVCEAVGYASYIPGQQVTVNLNVERYNDVGSRPESACTEYQATCMNGECIDKSSICDGNPDCSDASDEQSCSLGLKCQPNQFMCSNSKCVDRTWRCDGENDCGDNSDETSCDPEPSGAPCRYNEFQCRSGHCIPKSFQCDNVPDCTDGTDEVGCMAPLPIRPPPQSVSLLEYEVLELTCVATGTPTPTIVWRLNWGHVPDKCESKSYGGTGTLRCPDMRPQDSGAYSCEIINTRGTHFVNPDTIVTVRPVRTDVCEAGFFNMLARKAEECVQCFCFGVAKACDSANLFTYAIHPPILSHRVVSVELSPLRQIVINEAAPGQDLLTLLHGVQFRATNVHFSGRETPYLALPADYMGNQLKSYGGNLRYEVNYRGSGRPVNGPDVIITGNRFTLTYRVRTQPGQNNRVSIPFVPGGWQKPDGRKASREEIMMILANVDNILIRLGYLDSTAREVDLINIALDSAGTADKGLGSASLVEKCQCPPGYVGDSCESCASGYVRQPGGPWLGHCVPFIPDSCPSGTYGDPRRGVPCKECPCPLTGSNNFASGCQQSPDGDVVCRCNEGYTGRRCEQCAAGYQGNPLAAGGICRRIPDTSCNVDGTYSVHSNGTCQCKDSVIGEQCDTCKSKSFHLNSFTYTGCIECFCSGVGLDCDSSTWYRDQVTSTFGRSRVDHGFVLVTNYMQPTPDTVPVSMAAEPNALSFIGSADQSGNTLYWSLPAAFLGNKLSSYGGKLTYTLSYSPLPNGIMSRNSAPDVVIKSGEDLRLIHYRKSQVVPSVANTYSVEIKESAWQRGDEVVANREHVLMALSDITAIYIKATYTTSTKEASLRQVTLDVATPTNLGTPRAVEVEQCRCPEGYLGLSCEQCAPGYARDPEGGIYLGLCRPCECNGHSKYCNSDTGDCEECSDNTEGPSCERCAAGYVGDATRGTIYDCQPDEGYPIPSPPAPGNQTLECTAYCQIEGIYDCRGNECLCKRNVIGDQCDQCRPGTYGLSAQNQDGCKECYCSGLASQCRSAALYRQLIPVDFILNAPLITDESGAVQDTENLIPDISRNMYTYTHTSYLPKYWSLRGSVLGNQLFSYGGRLSYSLIVESYGNYERGHDIVLIGNGLKLIWSRPDGNENQEEYNVRLHEDEQWTRQDRESARPASRSDFMTVLSDLQHILIRATPRVPTQSTSIGNVILESAVTTRTPGATHASDIELCQCPSGYVGTSCESCAPLHYRDASGSCSLCPCDVSNTESCDLVSGGYVECRCKARWKGDRCREIDTNDPTDIGTEDPVLTQIIVSIQKPEITIVPVGGSMTLSCSGRMRWSNSPVIVNWYKENSRLPENVEVQGGNLYLYDLQVSDSGVYICQAVNNETASVFKDTVSITITRYAQEMLARYEKDQLSPAEIVNLPSHVTFEEYVNNEIICEVLGNPAPRVTWARVDGHADAQSTRTYDNRLIFDSPRKSDEGRYRCQAENDQNRDEKYVIVYVQSNPPQPPPQQDRLYITPEEINGLAGESFQLNCQFTSVASLRYDWSHNGRSLSSSPARNVEIRGNTLEVRDASESDSGVYTCVAYDVRTRRNFTESARVNIDRREEQPFGNKPIIESLEQNILIIQGEDYSITCEASGSPYPSIKWAKVHDFMPENVHISGNVLTIYGARFENRGVYSCVAENDHGSDLSSTSIDIEPRERPSVKIVSAPLQTFSVGAPASLYCTVEGIPDPTVEWVRVDGQPLSPRHKIQSPGYMVIDDIQLEDSGDYECRAKNIVGEATGVATITVQEPTLVQIIPDNRDLRLTEGDELSLTCVGSGVPNPEVEWVNEMALKRDLYSPPSNTAILKIYRVTKADAGIYTCHGKNEAGSDEAHVRVEVQERRGDIGGVDDDSDRDPINYNPPQQQNPGIHQPGSNQLLATDIGDNVTLTCDMFQPLNTRWERVDGAPLPRNAYTIKNRLEIVRVEQQNLGQYRCNGIGRDGNVKTYFVKELVLMPLPRIRFYPNIPLTVEAGQNLDVHCQVENVRPEDVHWSTDNNRPLPSSVRIVGSVLRFVSITQAAAGEYRCSAFNQYGNRSQIARVAVKKPADFHQVPQSQLQRHREGENIQLQCTVTDQYGVRAQDNVEFNWFRDDRRPLPNNARTDSQILVLTNLRPEDAGRYICNSYDVDRGQQLPEVSIDLQVLRAPQYPYNRFKGGVSLKDTPCMVLYICAAATPPPNSPIYLPPQLPAKSRDYSLKLDDQSSNLRAGESTDVECYSSDDTYTDVVWERSDGAPLSNNVRQVGNRLVISNVSPSDAGNYVCKCKTDEGDLYTTSYKLEVEDQPHELKSSKIVYAKVGANADLQCGADESRQPTYRWSRQYGQLQAGRSLMNEKLSLDSVQANDAGTYICTAQYADGETADFPNILVVTGAIPQFRQEPRSYMSFPTLPNSSFKFNFELTFRPENGDGLLLFNGQTRGSGDYIALSLKDRYAEFRFDFGGKPMLVRAEEPLALNEWHTVRVSRFKRDGYIQVDEQHPVAFPTLQQIPQLDLIEDLYIGGVPNWELLPADAVSQQVGFVGCISRLTLQGRTVELIREAKYKEGITDCRPCAQGPCQNKGVCLESQTEQAYTCICQPGWTGRDCAIEGTQCTPGVCGAGRCENTENDMECLCPLNRSGDRCQYNEILNEHSLNFKGNSFAAYGTPKVTKVNITLSVRPASLEDSVILYTAESTLPSGDYLALVLRGGHAELLINTAARLDPVVVRSAEPLPLNRWTRIEIRRRLGEGILRVGDGPERKAKAPGSDRILSLKTHLYVGGYDRSTVKVNRDVNITKGFDGCISRLYNFQKPVNLLADIKDAANIQSCGETNMIGGDEDSDNEPPVPPPTPDVHENELQPYAMAPCASDPCENGGSCSEQEDVAVCSCPFGFSGKHCQEHLQLGFNASFRGDGYVELNRSHFQPALEQSYTSMGIVFTTNKPNGLLFWWGQEAGEEYTGQDFIAAAVVDGYVEYSMRLDGEEAVIRNSDIRVDNGERHIVIAKRDENTAILEVDRMLHSGETRPTSKKSMKLPGNVFVGGAPDLEVFTGFRYKHNLNGCIVVVEGETVGQINLSSAAVNGVNANVCPANDDPLGGTEPPVV", "length": 4489, "header": "tr|A0ACD4DAU3-1|A0ACD4DAU3_DROME Isoform 1 of Terribly reduced optic lobes, isoform BD OS=Drosophila melanogaster OX=7227 GN=trol PE=1 SV=1 CANONICAL=A0ACD4DAU3-1" }, "locus": {} }, { "isoform_ac": "A0ACD4DAU7-1", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3/entry#A0ACD4DAU7-1", "sequence": { "sequence": "MMGSPGSQASAIATSVGIRSGRRGQAGGSLLLRLLAVTFVLAACHAPLLTNAKQISNLGDDQDFMLADDESLQGINDSEWQLMGDDIDDGLLDDVDETLKPMETKSEEEDLPTGNWFSQSVHRVRRSINRLFGSDDNQERGRRQQRERSQRNRDAINRQKELRRRQKEDHNRWKQMRMERQLEKQRLVKRTNHVVFNRATDPRKRASDLYDENEASGYHEEDTTLYRTYFVVNEPYDNEYRDRESVQFQNLQKLLDDDLRNFFHSNYEGNDDEEQEIRSTLERVEPTNDNFKIRVQLRIELPTSVNDFGSKLQQQLNVYNRIENLSAATDGVFSFTESSDIEEEAIDVTLPQEEVEGSGSDDSSCRGDATFTCPRSGKTICDEMRCDREIQCPDGEDEEYCNYPNVCTEDQFKCDDKCLELKKRCDGSIDCLDQTDEAGCINAPEPEPEPEPEPEPEPESEPEAEPEPEPEPEPESEPEQEPEPQVPEANECQANEFRCNNGDCIDARKRCNNVSDCSEGEDENEECRCYANQFRCNNGDCVSGSAPCNGYSECSDHSDELNCGGTQECLPNQFRCNSGQCVSSSVRCNGRTDCQDSSDEQNCAADSNDRRPNQLNLKTYPDSQIIKESREVIFRCRDEGPARAKVKWSRPGGRPLPPGFTDRNGRLEIPNIRVEDAGTYVCEAVGYASYIPGQQVTVNLNVERYNDVGSRPESACTEYQATCMNGECIDKSSICDGNPDCSDASDEQSCSLGLKCQPNQFMCSNSKCVDRTWRCDGENDCGDNSDETSCDPEPSGAPCRYNEFQCRSGHCIPKSFQCDNVPDCTDGTDEVGCMAPLPIRPPPQSVSLLEYEVLELTCVATGTPTPTIVWRLNWGHVPDKCESKSYGGTGTLRCPDMRPQDSGAYSCEIINTRGTHFVNPDTIVTVRPVRTDVCEAGFFNMLARKAEECVQCFCFGVAKACDSANLFTYAIHPPILSHRVVSVELSPLRQIVINEAAPGQDLLTLLHGVQFRATNVHFSGRETPYLALPADYMGNQLKSYGGNLRYEVNYRGSGRPVNGPDVIITGNRFTLTYRVRTQPGQNNRVSIPFVPGGWQKPDGRKASREEIMMILANVDNILIRLGYLDSTAREVDLINIALDSAGTADKGLGSASLVEKCQCPPGYVGDSCESCASGYVRQPGGPWLGHCVPFIPDSCPSGTYGDPRRGVPCKECPCPLTGSNNFASGCQQSPDGDVVCRCNEGYTGRRCEQCAAGYQGNPLAAGGICRRIPDTSCNVDGTYSVHSNGTCQCKDSVIGEQCDTCKSKSFHLNSFTYTGCIECFCSGVGLDCDSSTWYRDQVTSTFGRSRVDHGFVLVTNYMQPTPDTVPVSMAAEPNALSFIGSADQSGNTLYWSLPAAFLGNKLSSYGGKLTYTLSYSPLPNGIMSRNSAPDVVIKSGEDLRLIHYRKSQVVPSVANTYSVEIKESAWQRGDEVVANREHVLMALSDITAIYIKATYTTSTKEASLRQVTLDVATPTNLGTPRAVEVEQCRCPEGYLGLSCEQCAPGYARDPEGGIYLGLCRPCECNGHSKYCNSDTGDCEECSDNTEGPSCERCAAGYVGDATRGTIYDCQPDEGYPIPSPPAPGNQTLECTAYCQIEGIYDCRGNECLCKRNVIGDQCDQCRPGTYGLSAQNQDGCKECYCSGLASQCRSAALYRQLIPVDFILNAPLITDESGAVQDTENLIPDISRNMYTYTHTSYLPKYWSLRGSVLGNQLFSYGGRLSYSLIVESYGNYERGHDIVLIGNGLKLIWSRPDGNENQEEYNVRLHEDEQWTRQDRESARPASRSDFMTVLSDLQHILIRATPRVPTQSTSIGNVILESAVTTRTPGATHASDIELCQCPSGYVGTSCESCAPLHYRDASGSCSLCPCDVSNTESCDLVSGGYVECRCKARWKGDRCREIDTNDPTDIGTEDPVLTQIIVSIQKPEITIVPVGGSMTLSCSGRMRWSNSPVIVNWYKENSRLPENVEVQGGNLYLYDLQVSDSGVYICQAVNNETASVFKDTVSITITRYAQEMLARYEKDQLSPAEIVNLPSHVTFEEYVNNEIICEVLGNPAPRVTWARVDGHADAQSTRTYDNRLIFDSPRKSDEGRYRCQAENDQNRDEKYVIVYVQSNPPQPPPQQDRLYITPEEINGLAGESFQLNCQFTSVASLRYDWSHNGRSLSSSPARNVEIRGNTLEVRDASESDSGVYTCVAYDVRTRRNFTESARVNIDRREEQPFGNKPIIESLEQNILIIQGEDYSITCEASGSPYPSIKWAKVHDFMPENVHISGNVLTIYGARFENRGVYSCVAENDHGSDLSSTSIDIEPRERPSVKIVSAPLQTFSVGAPASLYCTVEGIPDPTVEWVRVDGQPLSPRHKIQSPGYMVIDDIQLEDSGDYECRAKNIVGEATGVATITVQEPTLVQIIPDNRDLRLTEGDELSLTCVGSGVPNPEVEWVNEMALKRDLYSPPSNTAILKIYRVTKADAGIYTCHGKNEAGSDEAHVRVEVQERRGDIGGVDDDSDRDPINYNPPQQQNPGIHQPGSNQLLATDIGDNVTLTCDMFQPLNTRWERVDGAPLPRNAYTIKNRLEIVRVEQQNLGQYRCNGIGRDGNVKTYFVKELVLMPLPRIRFYPNIPLTVEAGQNLDVHCQVENVRPEDVHWSTDNNRPLPSSVRIVGSVLRFVSITQAAAGEYRCSAFNQYGNRSQIARVAVKKPADFHQVPQSQLQRHREGENIQLQCTVTDQYGVRAQDNVEFNWFRDDRRPLPNNARTDSQILVLTNLRPEDAGRYICNSYDVDRGQQLPEVSIDLQVLTATPPPNSPIYLPPQLPAKSRDYSLKLDDQSSNLRAGESTDVECYSSDDTYTDVVWERSDGAPLSNNVRQVGNRLVISNVSPSDAGNYVCKCKTDEGDLYTTSYKLEVEDQPHELKSSKIVYAKVGANADLQCGADESRQPTYRWSRQYGQLQAGRSLMNEKLSLDSVQANDAGTYICTAQYADGETADFPNILVVTGAIPQFRQEPRSYMSFPTLPNSSFKFNFELTFRPENGDGLLLFNGQTRGSGDYIALSLKDRYAEFRFDFGGKPMLVRAEEPLALNEWHTVRVSRFKRDGYIQVDEQHPVAFPTLQQIPQLDLIEDLYIGGVPNWELLPADAVSQQVGFVGCISRLTLQGRTVELIREAKYKEGITDCRPCAQGPCQNKGVCLESQTEQAYTCICQPGWTGRDCAIEGTQCTPGVCGAGRCENTENDMECLCPLNRSGDRCQYNEILNEHSLNFKGNSFAAYGTPKVTKVNITLSVRPASLEDSVILYTAESTLPSGDYLALVLRGGHAELLINTAARLDPVVVRSAEPLPLNRWTRIEIRRRLGEGILRVGDGPERKAKAPGSDRILSLKTHLYVGGYDRSTVKVNRDVNITKGFDGCISRLYNFQKPVNLLADIKDAANIQSCGETNMIGGDEDSDNEPPVPPPTPDVHENELQPYAMAPCASDPCENGGSCSEQEDVAVCSCPFGFSGKHCQEHLQLGFNASFRGDGYVELNRSHFQPALEQSYTSMGIVFTTNKPNGLLFWWGQEAGEEYTGQDFIAAAVVDGYVEYSMRLDGEEAVIRNSDIRVDNGERHIVIAKRDENTAILEVDRMLHSGETRPTSKKSMKLPGNVFVGGAPDLEVFTGFRYKHNLNGCIVVVEGETVGQINLSSAAVNGVNANVCPANDDPLGGTEPPVV", "length": 3738, "header": "tr|A0ACD4DAU7-1|A0ACD4DAU7_DROME Computationally mapped isoform of Terribly reduced optic lobes, isoform BE OS=Drosophila melanogaster OX=7227 GN=trol PE=1 SV=1 CANONICAL=A0ACD4DAU3-1" }, "locus": {} }, { "isoform_ac": "E1JJC0-1", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3/entry#E1JJC0-1", "sequence": { "sequence": "MMGSPGSQASAIATSVGIRSGRRGQAGGSLLLRLLAVTFVLAACHAPLLTNAKQISNLGDDQDFMLADDESLQGINDSEWQLMGDDIDDGLLDDVDETLKPMETKSEEEDLPTGNWFSQSVHRVRRSINRLFGSDDNQERGRRQQRERSQRNRDAINRQKELRRRQKEDHNRWKQMRMERQLEKQRLVKRTNHVVFNRATDPRKRASDLYDENEASGYHEEDTTLYRTYFVVNEPYDNEYRDRESVQFQNLQKLLDDDLRNFFHSNYEGNDDEEQEIRSTLERVEPTNDNFKIRVQLRIELPTSVNDFGSKLQQQLNVYNRIENLSAATDGVFSFTESSDIEEEAIDVTLPQEEVEGSGSDDSSCRGDATFTCPRSGKTICDEMRCDREIQCPDGEDEEYCNYPNVCTEDQFKCDDKCLELKKRCDGSIDCLDQTDEAGCINAPEPEPEPEPEPEPEPESEPEAEPEPEPEPEPESEPEQEPEPQVPEANECQANEFRCNNGDCIDARKRCNNVSDCSEGEDENEECPAACSGMEYQCRDGTRCISVSQQCDGHSDCSDGDDEEHCDGSGYDSEECRFDEFHCGTGECIPMRQVCDNIYDCNDYSDEVNCVEGEEEDRVGIPIGHQPWRPASKHDDWLHEMDTSEYQVYQPSNVYEKANSQNPCASNQFRCTTSNVCIPLHLRCDGFYHCNDMSDEKSCEQYQRHTTTRRPLTLATPTSRITTQGPGLLERRNTTTATEASRWPWATKTTTIATTTSNPITTVGVANSPPQTCLENIEFACHNRDCISIESVCDGIPDCGRNEDEDDALCKCSGDKYKCQRGGGCIPKSQVCDGKPQCHDRSDESACHLHGRLNKTRLGVKCLESQYQCGDGSCISGYKRCNGIHDCADASDEYNCIYDYEDTYDTDPNNNPLNECDILEFECDYSQCLPLEKKCDGYADCEDMSDELECQSYTDHCLESEFECDSYCLPRDQLCNGIPNCQDGSDERNCTFCREDAYLCNTGECVADNQRCNGIADCADGSDERHCARIYCPPNKLACNGTCVSRRIKCDGIRDCLDGYDEMYCPETNNHYPTQNVNVIRPKLGPNPIPKSCRPHEWQCANLECIDSSLQCNEIKDCSDGSDEELSVCFGTATTRLKPSDCSPEQFYCDESCYNRSVRCNGHVDCSDGSDEVGCSLPCPQHQCPSGRCYTESERCDRHRHCEDGSDEANCCYANQFRCNNGDCVSGSAPCNGYSECSDHSDELNCGGTQECLPNQFRCNSGQCVSSSVRCNGRTDCQDSSDEQNCAADSNDRRPNQLNLKTYPDSQIIKESREVIFRCRDEGPARAKVKWSRPGGRPLPPGFTDRNGRLEIPNIRVEDAGTYVCEAVGYASYIPGQQVTVNLNVERYNDVGSRPESACTEYQATCMNGECIDKSSICDGNPDCSDASDEQSCSLGLKCQPNQFMCSNSKCVDRTWRCDGENDCGDNSDETSCDPEPSGAPCRYNEFQCRSGHCIPKSFQCDNVPDCTDGTDEVGCMAPLPIRPPPQSVSLLEYEVLELTCVATGTPTPTIVWRLNWGHVPDKCESKSYGGTGTLRCPDMRPQDSGAYSCEIINTRGTHFVNPDTIVTVRPVRTDVCEAGFFNMLARKAEECVQCFCFGVAKACDSANLFTYAIHPPILSHRVVSVELSPLRQIVINEAAPGQDLLTLLHGVQFRATNVHFSGRETPYLALPADYMGNQLKSYGGNLRYEVNYRGSGRPVNGPDVIITGNRFTLTYRVRTQPGQNNRVSIPFVPGGWQKPDGRKASREEIMMILANVDNILIRLGYLDSTAREVDLINIALDSAGTADKGLGSASLVEKCQCPPGYVGDSCESCASGYVRQPGGPWLGHCVPFIPDSCPSGTYGDPRRGVPCKECPCPLTGSNNFASGCQQSPDGDVVCRCNEGYTGRRCEQCAAGYQGNPLAAGGICRRIPDTSCNVDGTYSVHSNGTCQCKDSVIGEQCDTCKSKSFHLNSFTYTGCIECFCSGVGLDCDSSTWYRDQVTSTFGRSRVDHGFVLVTNYMQPTPDTVPVSMAAEPNALSFIGSADQSGNTLYWSLPAAFLGNKLSSYGGKLTYTLSYSPLPNGIMSRNSAPDVVIKSGEDLRLIHYRKSQVVPSVANTYSVEIKESAWQRGDEVVANREHVLMALSDITAIYIKATYTTSTKEASLRQVTLDVATPTNLGTPRAVEVEQCRCPEGYLGLSCEQCAPGYARDPEGGIYLGLCRPCECNGHSKYCNSDTGDCEECSDNTEGPSCERCAAGYVGDATRGTIYDCQPDEGYPIPSPPAPGNQTLECTAYCQIEGIYDCRGNECLCKRNVIGDQCDQCRPGTYGLSAQNQDGCKECYCSGLASQCRSAALYRQLIPVDFILNAPLITDESGAVQDTENLIPDISRNMYTYTHTSYLPKYWSLRGSVLGNQLFSYGGRLSYSLIVESYGNYERGHDIVLIGNGLKLIWSRPDGNENQEEYNVRLHEDEQWTRQDRESARPASRSDFMTVLSDLQHILIRATPRVPTQSTSIGNVILESAVTTRTPGATHASDIELCQCPSGYVGTSCESCAPLHYRDASGSCSLCPCDVSNTESCDLVSGGYVECRCKARWKGDRCREIDTNDPTDIGTEDPVLTQIIVSIQKPEITIVPVGGSMTLSCSGRMRWSNSPVIVNWYKENSRLPENVEVQGGNLYLYDLQVSDSGVYICQAVNNETASVFKDTVSITITKKDQLSPAEIVNLPSHVTFEEYVNNEIICEVLGNPAPRVTWARVDGHADAQSTRTYDNRLIFDSPRKSDEGRYRCQAENDQNRDEKYVIVYVQSNPPQPPPQQDRLYITPEEINGLAGESFQLNCQFTSVASLRYDWSHNGRSLSSSPARNVEIRGNTLEVRDASESDSGVYTCVAYDVRTRRNFTESARVNIDRREEQPFGNKPIIESLEQNILIIQGEDYSITCEASGSPYPSIKWAKVHDFMPENVHISGNVLTIYGARFENRGVYSCVAENDHGSDLSSTSIDIEPRERPSVKIVSAPLQTFSVGAPASLYCTVEGIPDPTVEWVRVDGQPLSPRHKIQSPGYMVIDDIQLEDSGDYECRAKNIVGEATGVATITVQEPTLVQIIPDNRDLRLTEGDELSLTCVGSGVPNPEVEWVNEMALKRDLYSPPSNTAILKIYRVTKADAGIYTCHGKNEAGSDEAHVRVEVQERRGDIGGVDDDSDRDPINYNPPQQQNPGIHQPGSNQLLATDIGDNVTLTCDMFQPLNTRWERVDGAPLPRNAYTIKNRLEIVRVEQQNLGQYRCNGIGRDGNVKTYFVKELVLMPLPRIRFYPNIPLTVEAGQNLDVHCQVENVRPEDVHWSTDNNRPLPSSVRIVGSVLRFVSITQAAAGEYRCSAFNQYGNRSQIARVAVKKPADFHQVPQSQLQRHREGENIQLQCTVTDQYGVRAQDNVEFNWFRDDRRPLPNNARTDSQILVLTNLRPEDAGRYICNSYDVDRGQQLPEVSIDLQVLTATPPPNSPIYLPPQLPAKSRDYSLKLDDQSSNLRAGESTDVECYSSDDTYTDVVWERSDGAPLSNNVRQVGNRLVISNVSPSDAGNYVCKCKTDEGDLYTTSYKLEVEDQPHELKSSKIVYAKVGANADLQCGADESRQPTYRWSRQYGQLQAGRSLMNEKLSLDSVQANDAGTYICTAQYADGETADFPNILVVTGAIPQFRQEPRSYMSFPTLPNSSFKFNFELTFRPENGDGLLLFNGQTRGSGDYIALSLKDRYAEFRFDFGGKPMLVRAEEPLALNEWHTVRVSRFKRDGYIQVDEQHPVAFPTLQQIPQLDLIEDLYIGGVPNWELLPADAVSQQVGFVGCISRLTLQGRTVELIREAKYKEGITDCRPCAQGPCQNKGVCLESQTEQAYTCICQPGWTGRDCAIEGTQCTPGVCGAGRCENTENDMECLCPLNRSGDRCQYNEILNEHSLNFKGNSFAAYGTPKVTKVNITLSVRPASLEDSVILYTAESTLPSGDYLALVLRGGHAELLINTAARLDPVVVRSAEPLPLNRWTRIEIRRRLGEGILRVGDGPERKAKAPGSDRILSLKTHLYVGGYDRSTVKVNRDVNITKGFDGCISRLYNFQKPVNLLADIKDAANIQSCGETNMIGGDEDSDNEPPVPPPTPDVHENELQPYAMAPCASDPCENGGSCSEQEDVAVCSCPFGFSGKHCQEHLQLGFNASFRGDGYVELNRSHFQPALEQSYTSMGIVFTTNKPNGLLFWWGQEAGEEYTGQDFIAAAVVDGYVEYSMRLDGEEAVIRNSDIRVDNGERHIVIAKRDENTAILEVDRMLHSGETRPTSKKSMKLPGNVFVGGAPDLEVFTGFRYKHNLNGCIVVVEGETVGQINLSSAAVNGVNANVCPANDDPLGGTEPPVV", "length": 4411, "header": "tr|E1JJC0-1|A0ACD4DAU3_DROME Computationally mapped isoform of Terribly reduced optic lobes, isoform BD OS=Drosophila melanogaster OX=7227 GN=trol PE=1 SV=3 CANONICAL=A0ACD4DAU3-1" }, "locus": {} }, { "isoform_ac": "M9NDL5-1", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3/entry#M9NDL5-1", "sequence": { "sequence": "MMGSPGSQASAIATSVGIRSGRRGQAGGSLLLRLLAVTFVLAACHAPLLTNAKQISNLGDDQDFMLADDESLQGINDSEWQLMGDDIDDGLLDDVDETLKPMETKSEEEDLPTGNWFSQSVHRVRRSINRLFGSDDNQERGRRQQRERSQRNRDAINRQKELRRRQKEDHNRWKQMRMERQLEKQRLVKRTNHVVFNRATDPRKRASDLYDENEASGYHEEDTTLYRTYFVVNEPYDNEYRDRESVQFQNLQKLLDDDLRNFFHSNYEGNDDEEQEIRSTLERVEPTNDNFKIRVQLRIELPTSVNDFGSKLQQQLNVYNRIENLSAATDGVFSFTESSDIEEEAIDVTLPQEEVEGSGSDDSSCRGDATFTCPRSGKTICDEMRCDREIQCPDGEDEEYCNYPNVCTEDQFKCDDKCLELKKRCDGSIDCLDQTDEAGCINAPEPEPEPEPEPEPEPESEPEAEPEPEPEPEPESEPEQEPEPQVPEANECQANEFRCNNGDCIDARKRCNNVSDCSEGEDENEECPAACSGMEYQCRDGTRCISVSQQCDGHSDCSDGDDEEHCDGSGYDSEECRFDEFHCGTGECIPMRQVCDNIYDCNDYSDEVNCVEGEEEDRVGIPIGHQPWRPASKHDDWLHEMDTSEYQVYQPSNVYEKANSQNPCASNQFRCTTSNVCIPLHLRCDGFYHCNDMSDEKSCEQYQRHTTTRRPLTLATPTSRITTQGPGLLERRNTTTATEASRWPWATKTTTIATTTSNPITTVGVANSPPQTCLENIEFACHNRDCISIESVCDGIPDCGRNEDEDDALCKCSGDKYKCQRGGGCIPKSQVCDGKPQCHDRSDESACHLHGRLNKTRLGVKCLESQYQCGDGSCISGYKRCNGIHDCADASDEYNCIYDYEDTYDTDPNNNPLNECDILEFECDYSQCLPLEKKCDGYADCEDMSDELECQSYTDHCLESEFECDSYCLPRDQLCNGIPNCQDGSDERNCTFCREDAYLCNTGECVADNQRCNGIADCADGSDERHCETNNHYPTQNVNVIRPKLGPNPIPKSCRPHEWQCANLECIDSSLQCNEIKDCSDGSDEELSVCFGTATTRLKPSDCSPEQFYCDESCYNRSVRCNGHVDCSDGSDEVGCSLPCPQHQCPSGRCYTESERCDRHRHCEDGSDEANCCYANQFRCNNGDCVSGSAPCNGYSECSDHSDELNCGGTQECLPNQFRCNSGQCVSSSVRCNGRTDCQDSSDEQNCAADSNDRRPNQLNLKTYPDSQIIKESREVIFRCRDEGPARAKVKWSRPGGRPLPPGFTDRNGRLEIPNIRVEDAGTYVCEAVGYASYIPGQQVTVNLNVERYNDVGSRPESACTEYQATCMNGECIDKSSICDGNPDCSDASDEQSCSLGLKCQPNQFMCSNSKCVDRTWRCDGENDCGDNSDETSCDPEPSGAPCRYNEFQCRSGHCIPKSFQCDNVPDCTDGTDEVGCMAPLPIRPPPQSVSLLEYEVLELTCVATGTPTPTIVWRLNWGHVPDKCESKSYGGTGTLRCPDMRPQDSGAYSCEIINTRGTHFVNPDTIVTVRPVRTDVCEAGFFNMLARKAEECVQCFCFGVAKACDSANLFTYAIHPPILSHRVVSVELSPLRQIVINEAAPGQDLLTLLHGVQFRATNVHFSGRETPYLALPADYMGNQLKSYGGNLRYEVNYRGSGRPVNGPDVIITGNRFTLTYRVRTQPGQNNRVSIPFVPGGWQKPDGRKASREEIMMILANVDNILIRLGYLDSTAREVDLINIALDSAGTADKGLGSASLVEKCQCPPGYVGDSCESCASGYVRQPGGPWLGHCVPFIPDSCPSGTYGDPRRGVPCKECPCPLTGSNNFASGCQQSPDGDVVCRCNEGYTGRRCEQCAAGYQGNPLAAGGICRRIPDTSCNVDGTYSVHSNGTCQCKDSVIGEQCDTCKSKSFHLNSFTYTGCIECFCSGVGLDCDSSTWYRDQVTSTFGRSRVDHGFVLVTNYMQPTPDTVPVSMAAEPNALSFIGSADQSGNTLYWSLPAAFLGNKLSSYGGKLTYTLSYSPLPNGIMSRNSAPDVVIKSGEDLRLIHYRKSQVVPSVANTYSVEIKESAWQRGDEVVANREHVLMALSDITAIYIKATYTTSTKEASLRQVTLDVATPTNLGTPRAVEVEQCRCPEGYLGLSCEQCAPGYARDPEGGIYLGLCRPCECNGHSKYCNSDTGDCEECSDNTEGPSCERCAAGYVGDATRGTIYDCQPDEGYPIPSPPAPGNQTLECTAYCQIEGIYDCRGNECLCKRNVIGDQCDQCRPGTYGLSAQNQDGCKECYCSGLASQCRSAALYRQLIPVDFILNAPLITDESGAVQDTENLIPDISRNMYTYTHTSYLPKYWSLRGSVLGNQLFSYGGRLSYSLIVESYGNYERGHDIVLIGNGLKLIWSRPDGNENQEEYNVRLHEDEQWTRQDRESARPASRSDFMTVLSDLQHILIRATPRVPTQSTSIGNVILESAVTTRTPGATHASDIELCQCPSGYVGTSCESCAPLHYRDASGSCSLCPCDVSNTESCDLVSGGYVECRCKARWKGDRCREIDTSPIIEDPPQICDLSRGFCCSGFQFDIAPNETISFNDTLQIYKGNRIIGNMTKLRYGCPSRDTNDPTDIGTEDPVLTQIIVSIQKPEITIVPVGGSMTLSCSGRMRWSNSPVIVNWYKENSRLPENVEVQGGNLYLYDLQVSDSGVYICQAVNNETASVFKDTVSITITKKDQLSPAEIVNLPSHVTFEEYVNNEIICEVLGNPAPRVTWARVDGHADAQSTRTYDNRLIFDSPRKSDEGRYRCQAENDQNRDEKYVIVYVQSNPPQPPPQQDRLYITPEEINGLAGESFQLNCQFTSVASLRYDWSHNGRSLSSSPARNVEIRGNTLEVRDASESDSGVYTCVAYDVRTRRNFTESARVNIDRREEQPFGNKPIIESLEQNILIIQGEDYSITCEASGSPYPSIKWAKVHDFMPENVHISGNVLTIYGARFENRGVYSCVAENDHGSDLSSTSIDIEPRERPSVKIVSAPLQTFSVGAPASLYCTVEGIPDPTVEWVRVDGQPLSPRHKIQSPGYMVIDDIQLEDSGDYECRAKNIVGEATGVATITVQEPTLVQIIPDNRDLRLTEGDELSLTCVGSGVPNPEVEWVNEMALKRDLYSPPSNTAILKIYRVTKADAGIYTCHGKNEAGSDEAHVRVEVQERRGDIGGVDDDSDRDPINYNPPQQQNPGIHQPGSNQLLATDIGDNVTLTCDMFQPLNTRWERVDGAPLPRNAYTIKNRLEIVRVEQQNLGQYRCNGIGRDGNVKTYFVKELVLMPLPRIRFYPNIPLTVEAGQNLDVHCQVENVRPEDVHWSTDNNRPLPSSVRIVGSVLRFVSITQAAAGEYRCSAFNQYGNRSQIARVAVKKPADFHQVPQSQLQRHREGENIQLQCTVTDQYGVRAQDNVEFNWFRDDRRPLPNNARTDSQILVLTNLRPEDAGRYICNSYDVDRGQQLPEVSIDLQVLTATPPPNSPIYLPPQLPAKSRDYSLKLDDQSSNLRAGESTDVECYSSDDTYTDVVWERSDGAPLSNNVRQVGNRLVISNVSPSDAGNYVCKCKTDEGDLYTTSYKLEVEDQPHELKSSKIVYAKVGANADLQCGADESRQPTYRWSRQYGQLQAGRSLMNEKLSLDSVQANDAGTYICTAQYADGETADFPNILVVTGAIPQFRQEPRSYMSFPTLPNSSFKFNFELTFRPENGDGLLLFNGQTRGSGDYIALSLKDRYAEFRFDFGGKPMLVRAEEPLALNEWHTVRVSRFKRDGYIQVDEQHPVAFPTLQQIPQLDLIEDLYIGGVPNWELLPADAVSQQVGFVGCISRLTLQGRTVELIREAKYKEGITDCRPCAQGPCQNKGVCLESQTEQAYTCICQPGWTGRDCAIEGTQCTPGVCGAGRCENTENDMECLCPLNRSGDRCQYNEILNEHSLNFKGNSFAAYGTPKVTKVNITLSVRPASLEDSVILYTAESTLPSGDYLALVLRGGHAELLINTAARLDPVVVRSAEPLPLNRWTRIEIRRRLGEGILRVGDGPERKAKAPGSDRILSLKTHLYVGGYDRSTVKVNRDVNITKGFDGCISRLYNFQKPVNLLADIKDAANIQSCGETNMIGGDEDSDNEPPVPPPTPDVHENELQPYAMAPCASDPCENGGSCSEQEDVAVCSCPFGFSGKHCQEHLQLGFNASFRGDGYVELNRSHFQPALEQSYTSMGIVFTTNKPNGLLFWWGQEAGEEYTGQDFIAAAVVDGYVEYSMRLDGEEAVIRNSDIRVDNGERHIVIAKRDENTAILEVDRMLHSGETRPTSKKSMKLPGNVFVGGAPDLEVFTGFRYKHNLNGCIVVVEGETVGQINLSSAAVNGVNANVCPANDDPLGGTEPPVV", "length": 4434, "header": "tr|M9NDL5-1|A0ACD4DAU3_DROME Computationally mapped isoform of Terribly reduced optic lobes, isoform BD OS=Drosophila melanogaster OX=7227 GN=trol PE=1 SV=2 CANONICAL=A0ACD4DAU3-1" }, "locus": {} }, { "isoform_ac": "M9NDM1-1", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3/entry#M9NDM1-1", "sequence": { "sequence": "MMGSPGSQASAIATSVGIRSGRRGQAGGSLLLRLLAVTFVLAACHAPLLTNAKQISNLGDDQDFMLADDESLQGINDSEWQLMGDDIDDGLLDDVDETLKPMETKSEEEDLPTGNWFSQSVHRVRRSINRLFGSDDNQERGRRQQRERSQRNRDAINRQKELRRRQKEDHNRWKQMRMERQLEKQRLVKRTNHVVFNRATDPRKRASDLYDENEASGYHEEDTTLYRTYFVVNEPYDNEYRDRESVQFQNLQKLLDDDLRNFFHSNYEGNDDEEQEIRSTLERVEPTNDNFKIRVQLRIELPTSVNDFGSKLQQQLNVYNRIENLSAATDGVFSFTESSDIEEEAIDVTLPQEEVEGSGSDDSSCRGDATFTCPRSGKTICDEMRCDREIQCPDGEDEEYCNYPNVCTEDQFKCDDKCLELKKRCDGSIDCLDQTDEAGCINAPEPEPEPEPEPEPEPESEPEAEPEPEPEPEPESEPEQEPEPQVPEANECQANEFRCNNGDCIDARKRCNNVSDCSEGEDENEECPTTRLKPSDCSPEQFYCDESCYNRSVRCNGHVDCSDGSDEVGCSLPCPQHQCPSGRCYTESERCDRHRHCEDGSDEANCCYANQFRCNNGDCVSGSAPCNGYSECSDHSDELNCGGTQECLPNQFRCNSGQCVSSSVRCNGRTDCQDSSDEQNCAADSNDRRPNQLNLKTYPDSQIIKESREVIFRCRDEGPARAKVKWSRPGGRPLPPGFTDRNGRLEIPNIRVEDAGTYVCEAVGYASYIPGQQVTVNLNVERYNDVGSRPESACTEYQATCMNGECIDKSSICDGNPDCSDASDEQSCSLGLKCQPNQFMCSNSKCVDRTWRCDGENDCGDNSDETSCDPEPSGAPCRYNEFQCRSGHCIPKSFQCDNVPDCTDGTDEVGCMAPLPIRPPPQSVSLLEYEVLELTCVATGTPTPTIVWRLNWGHVPDKCESKSYGGTGTLRCPDMRPQDSGAYSCEIINTRGTHFVNPDTIVTVRPVRTDVCEAGFFNMLARKAEECVQCFCFGVAKACDSANLFTYAIHPPILSHRVVSVELSPLRQIVINEAAPGQDLLTLLHGVQFRATNVHFSGRETPYLALPADYMGNQLKSYGGNLRYEVNYRGSGRPVNGPDVIITGNRFTLTYRVRTQPGQNNRVSIPFVPGGWQKPDGRKASREEIMMILANVDNILIRLGYLDSTAREVDLINIALDSAGTADKGLGSASLVEKCQCPPGYVGDSCESCASGYVRQPGGPWLGHCVPFIPDSCPSGTYGDPRRGVPCKECPCPLTGSNNFASGCQQSPDGDVVCRCNEGYTGRRCEQCAAGYQGNPLAAGGICRRIPDTSCNVDGTYSVHSNGTCQCKDSVIGEQCDTCKSKSFHLNSFTYTGCIECFCSGVGLDCDSSTWYRDQVTSTFGRSRVDHGFVLVTNYMQPTPDTVPVSMAAEPNALSFIGSADQSGNTLYWSLPAAFLGNKLSSYGGKLTYTLSYSPLPNGIMSRNSAPDVVIKSGEDLRLIHYRKSQVVPSVANTYSVEIKESAWQRGDEVVANREHVLMALSDITAIYIKATYTTSTKEASLRQVTLDVATPTNLGTPRAVEVEQCRCPEGYLGLSCEQCAPGYARDPEGGIYLGLCRPCECNGHSKYCNSDTGDCEECSDNTEGPSCERCAAGYVGDATRGTIYDCQPDEGYPIPSPPAPGNQTLECTAYCQIEGIYDCRGNECLCKRNVIGDQCDQCRPGTYGLSAQNQDGCKECYCSGLASQCRSAALYRQLIPVDFILNAPLITDESGAVQDTENLIPDISRNMYTYTHTSYLPKYWSLRGSVLGNQLFSYGGRLSYSLIVESYGNYERGHDIVLIGNGLKLIWSRPDGNENQEEYNVRLHEDEQWTRQDRESARPASRSDFMTVLSDLQHILIRATPRVPTQSTSIGNVILESAVTTRTPGATHASDIELCQCPSGYVGTSCESCAPLHYRDASGSCSLCPCDVSNTESCDLVSGGYVECRCKARWKGDRCREIDTNDPTDIGTEDPVLTQIIVSIQKPEITIVPVGGSMTLSCSGRMRWSNSPVIVNWYKENSRLPENVEVQGGNLYLYDLQVSDSGVYICQAVNNETASVFKDTVSITITKKDQLSPAEIVNLPSHVTFEEYVNNEIICEVLGNPAPRVTWARVDGHADAQSTRTYDNRLIFDSPRKSDEGRYRCQAENDQNRDEKYVIVYVQSNPPQPPPQQDRLYITPEEINGLAGESFQLNCQFTSVASLRYDWSHNGRSLSSSPARNVEIRGNTLEVRDASESDSGVYTCVAYDVRTRRNFTESARVNIDRREEQPFGNKPIIESLEQNILIIQGEDYSITCEASGSPYPSIKWAKVHDFMPENVHISGNVLTIYGARFENRGVYSCVAENDHGSDLSSTSIDIEPRERPSVKIVSAPLQTFSVGAPASLYCTVEGIPDPTVEWVRVDGQPLSPRHKIQSPGYMVIDDIQLEDSGDYECRAKNIVGEATGVATITVQEPTLVQIIPDNRDLRLTEGDELSLTCVGSGVPNPEVEWVNEMALKRDLYSPPSNTAILKIYRVTKADAGIYTCHGKNEAGSDEAHVRVEVQERRGDIGGVDDDSDRDPINYNPPQQQNPGIHQPGSNQLLATDIGDNVTLTCDMFQPLNTRWERVDGAPLPRNAYTIKNRLEIVRVEQQNLGQYRCNGIGRDGNVKTYFVKELVLMPLPRIRFYPNIPLTVEAGQNLDVHCQVENVRPEDVHWSTDNNRPLPSSVRIVGSVLRFVSITQAAAGEYRCSAFNQYGNRSQIARVAVKKPADFHQVPQSQLQRHREGENIQLQCTVTDQYGVRAQDNVEFNWFRDDRRPLPNNARTDSQILVLTNLRPEDAGRYICNSYDVDRGQQLPEVSIDLQVLTATPPPNSPIYLPPQLPAKSRDYSLKLDDQSSNLRAGESTDVECYSSDDTYTDVVWERSDGAPLSNNVRQVGNRLVISNVSPSDAGNYVCKCKTDEGDLYTTSYKLEVEDQPHELKSSKIVYAKVGANADLQCGADESRQPTYRWSRQYGQLQAGRSLMNEKLSLDSVQANDAGTYICTAQYADGETADFPNILVVTGAIPQFRQEPRSYMSFPTLPNSSFKFNFELTFRPENGDGLLLFNGQTRGSGDYIALSLKDRYAEFRFDFGGKPMLVRAEEPLALNEWHTVRVSRFKRDGYIQVDEQHPVAFPTLQQIPQLDLIEDLYIGGVPNWELLPADAVSQQVGFVGCISRLTLQGRTVELIREAKYKEGITDCRPCAQGPCQNKGVCLESQTEQAYTCICQPGWTGRDCAIEGTQCTPGVCGAGRCENTENDMECLCPLNRSGDRCQYNEILNEHSLNFKGNSFAAYGTPKVTKVNITLSVRPASLEDSVILYTAESTLPSGDYLALVLRGGHAELLINTAARLDPVVVRSAEPLPLNRWTRIEIRRRLGEGILRVGDGPERKAKAPGSDRILSLKTHLYVGGYDRSTVKVNRDVNITKGFDGCISRLYNFQKPVNLLADIKDAANIQSCGETNMIGGDEDSDNEPPVPPPTPDVHENELQPYAMAPCASDPCENGGSCSEQEDVAVCSCPFGFSGKHCQEHLQLGFNASFRGDGYVELNRSHFQPALEQSYTSMGIVFTTNKPNGLLFWWGQEAGEEYTGQDFIAAAVVDGYVEYSMRLDGEEAVIRNSDIRVDNGERHIVIAKRDENTAILEVDRMLHSGETRPTSKKSMKLPGNVFVGGAPDLEVFTGFRYKHNLNGCIVVVEGETVGQINLSSAAVNGVNANVCPANDDPLGGTEPPVV", "length": 3806, "header": "tr|M9NDM1-1|A0ACD4DAU3_DROME Computationally mapped isoform of Terribly reduced optic lobes, isoform BD OS=Drosophila melanogaster OX=7227 GN=trol PE=1 SV=2 CANONICAL=A0ACD4DAU3-1" }, "locus": {} }, { "isoform_ac": "M9NE56-1", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3/entry#M9NE56-1", "sequence": { "sequence": "MGRRLRAAFWLLAVLIVIEKPQKSVARGTYLSYGECQANEFRCNNGDCIDARKRCNNVSDCSEGEDENEECPAACSGMEYQCRDGTRCISVSQQCDGHSDCSDGDDEEHCDGIVPKLRYTCPKGKFTCRDLSCISIVHRCDGRADCPNDRSDEEGCPCLYDKWQCDDGTCIAKELLCNGNIDCPEDISDERYCEGGYDSEECRFDEFHCGTGECIPMRQVCDNIYDCNDYSDEVNCVEGEEEDRVGIPIGHQPWRPASKHDDWLHEMDTSEYQVYQPSNVYEKANSQNPCASNQFRCTTSNVCIPLHLRCDGFYHCNDMSDEKSCEQYQRHTTTRRPLTLATPTSRITTQGPGLLERRNTTTATEASRWPWATKTTTIATTTSNPITTVGVANSPPQTCLENIEFACHNRDCISIESVCDGIPDCGRNEDEDDALCKCSGDKYKCQRGGGCIPKSQVCDGKPQCHDRSDESACHLHGRLNKTRLGVKCLESQYQCGDGSCISGYKRCNGIHDCADASDEYNCIYDYEDTYDTDPNNNPLNECDILEFECDYSQCLPLEKKCDGYADCEDMSDELECQSYTDHCLESEFECDSYCLPRDQLCNGIPNCQDGSDERNCTFCREDAYLCNTGECVADNQRCNGIADCADGSDERHCARIYCPPNKLACNGTCVSRRIKCDGIRDCLDGYDEMYCPETNNHYPTQNVNVIRPKLGPNPIPKSCRPHEWQCANLECIDSSLQCNEIKDCSDGSDEELSVCFGTATTRLKPSDCSPEQFYCDESCYNRSVRCNGHVDCSDGSDEVGCSLPCPQHQCPSGRCYTESERCDRHRHCEDGSDEANCCYANQFRCNNGDCVSGSAPCNGYSECSDHSDELNCGGTQECLPNQFRCNSGQCVSSSVRCNGRTDCQDSSDEQNCGHRHTEVSQGLETTGVFTTSTTSTTAMTPLRIICPPTSFKCENGPCISLGLKCNGRVDCPYDGSDEADCGQISNDIDPADSNDRRPNQLNLKTYPDSQIIKESREVIFRCRDEGPARAKVKWSRPGGRPLPPGFTDRNGRLEIPNIRVEDAGTYVCEAVGYASYIPGQQVTVNLNVERYNDVGSRPESACTEYQATCMNGECIDKSSICDGNPDCSDASDEQSCSLGLKCQPNQFMCSNSKCVDRTWRCDGENDCGDNSDETSCDPEPSGAPCRYNEFQCRSGHCIPKSFQCDNVPDCTDGTDEVGCMAPLPIRPPPQSVSLLEYEVLELTCVATGTPTPTIVWRLNWGHVPDKCESKSYGGTGTLRCPDMRPQDSGAYSCEIINTRGTHFVNPDTIVTVRPVRTDVCEAGFFNMLARKAEECVQCFCFGVAKACDSANLFTYAIHPPILSHRVVSVELSPLRQIVINEAAPGQDLLTLLHGVQFRATNVHFSGRETPYLALPADYMGNQLKSYGGNLRYEVNYRGSGRPVNGPDVIITGNRFTLTYRVRTQPGQNNRVSIPFVPGGWQKPDGRKASREEIMMILANVDNILIRLGYLDSTAREVDLINIALDSAGTADKGLGSASLVEKCQCPPGYVGDSCESCASGYVRQPGGPWLGHCVPFIPDSCPSGTYGDPRRGVPCKECPCPLTGSNNFASGCQQSPDGDVVCRCNEGYTGRRCEQCAAGYQGNPLAAGGICRRIPDTSCNVDGTYSVHSNGTCQCKDSVIGEQCDTCKSKSFHLNSFTYTGCIECFCSGVGLDCDSSTWYRDQVTSTFGRSRVDHGFVLVTNYMQPTPDTVPVSMAAEPNALSFIGSADQSGNTLYWSLPAAFLGNKLSSYGGKLTYTLSYSPLPNGIMSRNSAPDVVIKSGEDLRLIHYRKSQVVPSVANTYSVEIKESAWQRGDEVVANREHVLMALSDITAIYIKATYTTSTKEASLRQVTLDVATPTNLGTPRAVEVEQCRCPEGYLGLSCEQCAPGYARDPEGGIYLGLCRPCECNGHSKYCNSDTGDCEECSDNTEGPSCERCAAGYVGDATRGTIYDCQPDEGYPIPSPPAPGNQTLECTAYCQIEGIYDCRGNECLCKRNVIGDQCDQCRPGTYGLSAQNQDGCKECYCSGLASQCRSAALYRQLIPVDFILNAPLITDESGAVQDTENLIPDISRNMYTYTHTSYLPKYWSLRGSVLGNQLFSYGGRLSYSLIVESYGNYERGHDIVLIGNGLKLIWSRPDGNENQEEYNVRLHEDEQWTRQDRESARPASRSDFMTVLSDLQHILIRATPRVPTQSTSIGNVILESAVTTRTPGATHASDIELCQCPSGYVGTSCESCAPLHYRDASGSCSLCPCDVSNTESCDLVSGGYVECRCKARWKGDRCREIDTSPIIEDPPQICDLSRGFCCSGFQFDIAPNETISFNDTLQIYKGNRIIGNMTKLRYGCPSRDTNDPTDIGTEDPVLTQIIVSIQKPEITIVPVGGSMTLSCSGRMRWSNSPVIVNWYKENSRLPENVEVQGGNLYLYDLQVSDSGVYICQAVNNETASVFKDTVSITITKKDQLSPAEIVNLPSHVTFEEYVNNEIICEVLGNPAPRVTWARVDGHADAQSTRTYDNRLIFDSPRKSDEGRYRCQAENDQNRDEKYVIVYVQSNPPQPPPQQDRLYITPEEINGLAGESFQLNCQFTSVASLRYDWSHNGRSLSSSPARNVEIRGNTLEVRDASESDSGVYTCVAYDVRTRRNFTESARVNIDRREEQPFGNKPIIESLEQNILIIQGEDYSITCEASGSPYPSIKWAKVHDFMPENVHISGNVLTIYGARFENRGVYSCVAENDHGSDLSSTSIDIEPRERPSVKIVSAPLQTFSVGAPASLYCTVEGIPDPTVEWVRVDGQPLSPRHKIQSPGYMVIDDIQLEDSGDYECRAKNIVGEATGVATITVQEPTLVQIIPDNRDLRLTEGDELSLTCVGSGVPNPEVEWVNEMALKRDLYSPPSNTAILKIYRVTKADAGIYTCHGKNEAGSDEAHVRVEVQERRGDIGGVDDDSDRDPINYNPPQQQNPGIHQPGSNQLLATDIGDNVTLTCDMFQPLNTRWERVDGAPLPRNAYTIKNRLEIVRVEQQNLGQYRCNGIGRDGNVKTYFVKELVLMPLPRIRFYPNIPLTVEAGQNLDVHCQVENVRPEDVHWSTDNNRPLPSSVRIVGSVLRFVSITQAAAGEYRCSAFNQYGNRSQIARVAVKKPADFHQVPQSQLQRHREGENIQLQCTVTDQYGVRAQDNVEFNWFRDDRRPLPNNARTDSQILVLTNLRPEDAGRYICNSYDVDRGQQLPEVSIDLQVLTATPPPNSPIYLPPQLPAKSRDYSLKLDDQSSNLRAGESTDVECYSSDDTYTDVVWERSDGAPLSNNVRQVGNRLVISNVSPSDAGNYVCKCKTDEGDLYTTSYKLEVEDQPHELKSSKIVYAKVGANADLQCGADESRQPTYRWSRQYGQLQAGRSLMNEKLSLDSVQANDAGTYICTAQYADGETADFPNILVVTGAIPQFRQEPRSYMSFPTLPNSSFKFNFELTFRPENGDGLLLFNGQTRGSGDYIALSLKDRYAEFRFDFGGKPMLVRAEEPLALNEWHTVRVSRFKRDGYIQVDEQHPVAFPTLQQIPQLDLIEDLYIGGVPNWELLPADAVSQQVGFVGCISRLTLQGRTVELIREAKYKEGITDCRPCAQGPCQNKGVCLESQTEQAYTCICQPGWTGRDCAIEGTQCTPGVCGAGRCENTENDMECLCPLNRSGDRCQYNEILNEHSLNFKGNSFAAYGTPKVTKVNITLSVRPASLEDSVILYTAESTLPSGDYLALVLRGGHAELLINTAARLDPVVVRSAEPLPLNRWTRIEIRRRLGEGILRVGDGPERKAKAPGSDRILSLKTHLYVGGYDRSTVKVNRDVNITKGFDGCISRLYNFQKPVNLLADIKDAANIQSCGETNMIGGDEDSDNEPPVPPPTPDVHENELQPYAMAPCASDPCENGGSCSEQEDVAVCSCPFGFSGKHCQEHLQLGFNASFRGDGYVELNRSHFQPALEQSYTSMGIVFTTNKPNGLLFWWGQEAGEEYTGQDFIAAAVVDGYVEYSMRLDGEEAVIRNSDIRVDNGERHIVIAKRDENTAILEVDRMLHSGETRPTSKKSMKLPGNVFVGGAPDLEVFTGFRYKHNLNGCIVVVEGETVGQINLSSAAVNGVNANVCPANDDPLGGTEPPVV", "length": 4176, "header": "tr|M9NE56-1|A0ACD4DAU3_DROME Computationally mapped isoform of Terribly reduced optic lobes, isoform BD OS=Drosophila melanogaster OX=7227 GN=trol PE=1 SV=1 CANONICAL=A0ACD4DAU3-1" }, "locus": {} }, { "isoform_ac": "M9NE61-1", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3/entry#M9NE61-1", "sequence": { "sequence": "MMGSPGSQASAIATSVGIRSGRRGQAGGSLLLRLLAVTFVLAACHAPLLTNAKQISNLGDDQDFMLADDESLQGINDSEWQLMGDDIDDGLLDDVDETLKPMETKSEEEDLPTGNWFSQSVHRVRRSINRLFGSDDNQERGRRQQRERSQRNRDAINRQKELRRRQKEDHNRWKQMRMERQLEKQRLVKRTNHVVFNRATDPRKRASDLYDENEASGYHEEDTTLYRTYFVVNEPYDNEYRDRESVQFQNLQKLLDDDLRNFFHSNYEGNDDEEQEIRSTLERVEPTNDNFKIRVQLRIELPTSVNDFGSKLQQQLNVYNRIENLSAATDGVFSFTESSDIEEEAIDVTLPQEEVEGSGSDDSSCRGDATFTCPRSGKTICDEMRCDREIQCPDGEDEEYCNYPNVCTEDQFKCDDKCLELKKRCDGSIDCLDQTDEAGCINAPEPEPEPEPEPEPEPESEPEAEPEPEPEPEPESEPEQEPEPQVPEANECQANEFRCNNGDCIDARKRCNNVSDCSEGEDENEECPAACSGMEYQCRDGTRCISVSQQCDGHSDCSDGDDEEHCDGSGYDSEECRFDEFHCGTGECIPMRQVCDNIYDCNDYSDEVNCVEGEEEDRVGIPIGHQPWRPASKHDDWLHEMDTSEYQVYQPSNVYEKANSQNPCASNQFRCTTSNVCIPLHLRCDGFYHCNDMSDEKSCEQYQRHTTTRRPLTLATPTSRITTQGPGLLERRNTTTATEASRWPWATKTTTIATTTSNPITTVGVATRIYCPPNKLACNGTCVSRRIKCDGIRDCLDGYDEMYCPETNNHYPTQNVNVIRPKLGPNPIPKSCRPHEWQCANLECIDSSLQCNEIKDCSDGSDEELSVCFGTATTRLKPSDCSPEQFYCDESCYNRSVRCNGHVDCSDGSDEVGCSLPCPQHQCPSGRCYTESERCDRHRHCEDGSDEANCCYANQFRCNNGDCVSGSAPCNGYSECSDHSDELNCGGTQECLPNQFRCNSGQCVSSSVRCNGRTDCQDSSDEQNCAADSNDRRPNQLNLKTYPDSQIIKESREVIFRCRDEGPARAKVKWSRPGGRPLPPGFTDRNGRLEIPNIRVEDAGTYVCEAVGYASYIPGQQVTVNLNVERYNDVGSRPESACTEYQATCMNGECIDKSSICDGNPDCSDASDEQSCSLGLKCQPNQFMCSNSKCVDRTWRCDGENDCGDNSDETSCDPEPSGAPCRYNEFQCRSGHCIPKSFQCDNVPDCTDGTDEVGCMAPLPIRPPPQSVSLLEYEVLELTCVATGTPTPTIVWRLNWGHVPDKCESKSYGGTGTLRCPDMRPQDSGAYSCEIINTRGTHFVNPDTIVTVRPVRTDVCEAGFFNMLARKAEECVQCFCFGVAKACDSANLFTYAIHPPILSHRVVSVELSPLRQIVINEAAPGQDLLTLLHGVQFRATNVHFSGRETPYLALPADYMGNQLKSYGGNLRYEVNYRGSGRPVNGPDVIITGNRFTLTYRVRTQPGQNNRVSIPFVPGGWQKPDGRKASREEIMMILANVDNILIRLGYLDSTAREVDLINIALDSAGTADKGLGSASLVEKCQCPPGYVGDSCESCASGYVRQPGGPWLGHCVPFIPDSCPSGTYGDPRRGVPCKECPCPLTGSNNFASGCQQSPDGDVVCRCNEGYTGRRCEQCAAGYQGNPLAAGGICRRIPDTSCNVDGTYSVHSNGTCQCKDSVIGEQCDTCKSKSFHLNSFTYTGCIECFCSGVGLDCDSSTWYRDQVTSTFGRSRVDHGFVLVTNYMQPTPDTVPVSMAAEPNALSFIGSADQSGNTLYWSLPAAFLGNKLSSYGGKLTYTLSYSPLPNGIMSRNSAPDVVIKSGEDLRLIHYRKSQVVPSVANTYSVEIKESAWQRGDEVVANREHVLMALSDITAIYIKATYTTSTKEASLRQVTLDVATPTNLGTPRAVEVEQCRCPEGYLGLSCEQCAPGYARDPEGGIYLGLCRPCECNGHSKYCNSDTGDCEECSDNTEGPSCERCAAGYVGDATRGTIYDCQPDEGYPIPSPPAPGNQTLECTAYCQIEGIYDCRGNECLCKRNVIGDQCDQCRPGTYGLSAQNQDGCKECYCSGLASQCRSAALYRQLIPVDFILNAPLITDESGAVQDTENLIPDISRNMYTYTHTSYLPKYWSLRGSVLGNQLFSYGGRLSYSLIVESYGNYERGHDIVLIGNGLKLIWSRPDGNENQEEYNVRLHEDEQWTRQDRESARPASRSDFMTVLSDLQHILIRATPRVPTQSTSIGNVILESAVTTRTPGATHASDIELCQCPSGYVGTSCESCAPLHYRDASGSCSLCPCDVSNTESCDLVSGGYVECRCKARWKGDRCREIDTNDPTDIGTEDPVLTQIIVSIQKPEITIVPVGGSMTLSCSGRMRWSNSPVIVNWYKENSRLPENVEVQGGNLYLYDLQVSDSGVYICQAVNNETASVFKDTVSITITKKDQLSPAEIVNLPSHVTFEEYVNNEIICEVLGNPAPRVTWARVDGHADAQSTRTYDNRLIFDSPRKSDEGRYRCQAENDQNRDEKYVIVYVQSNPPQPPPQQDRLYITPEEINGLAGESFQLNCQFTSVASLRYDWSHNGRSLSSSPARNVEIRGNTLEVRDASESDSGVYTCVAYDVRTRRNFTESARVNIDRREEQPFGNKPIIESLEQNILIIQGEDYSITCEASGSPYPSIKWAKVHDFMPENVHISGNVLTIYGARFENRGVYSCVAENDHGSDLSSTSIDIEPRERPSVKIVSAPLQTFSVGAPASLYCTVEGIPDPTVEWVRVDGQPLSPRHKIQSPGYMVIDDIQLEDSGDYECRAKNIVGEATGVATITVQEPTLVQIIPDNRDLRLTEGDELSLTCVGSGVPNPEVEWVNEMALKRDLYSPPSNTAILKIYRVTKADAGIYTCHGKNEAGSDEAHVRVEVQERRGDIGGVDDDSDRDPINYNPPQQQNPGIHQPGSNQLLATDIGDNVTLTCDMFQPLNTRWERVDGAPLPRNAYTIKNRLEIVRVEQQNLGQYRCNGIGRDGNVKTYFVKELVLMPLPRIRFYPNIPLTVEAGQNLDVHCQVENVRPEDVHWSTDNNRPLPSSVRIVGSVLRFVSITQAAAGEYRCSAFNQYGNRSQIARVAVKKPADFHQVPQSQLQRHREGENIQLQCTVTDQYGVRAQDNVEFNWFRDDRRPLPNNARTDSQILVLTNLRPEDAGRYICNSYDVDRGQQLPEVSIDLQVLTATPPPNSPIYLPPQLPAKSRDYSLKLDDQSSNLRAGESTDVECYSSDDTYTDVVWERSDGAPLSNNVRQVGNRLVISNVSPSDAGNYVCKCKTDEGDLYTTSYKLEVEDQPHELKSSKIVYAKVGANADLQCGADESRQPTYRWSRQYGQLQAGRSLMNEKLSLDSVQANDAGTYICTAQYADGETADFPNILVVTGAIPQFRQEPRSYMSFPTLPNSSFKFNFELTFRPENGDGLLLFNGQTRGSGDYIALSLKDRYAEFRFDFGGKPMLVRAEEPLALNEWHTVRVSRFKRDGYIQVDEQHPVAFPTLQQIPQLDLIEDLYIGGVPNWELLPADAVSQQVGFVGCISRLTLQGRTVELIREAKYKEGITDCRPCAQGPCQNKGVCLESQTEQAYTCICQPGWTGRDCAIEGTQCTPGVCGAGRCENTENDMECLCPLNRSGDRCQYNEILNEHSLNFKGNSFAAYGTPKVTKVNITLSVRPASLEDSVILYTAESTLPSGDYLALVLRGGHAELLINTAARLDPVVVRSAEPLPLNRWTRIEIRRRLGEGILRVGDGPERKAKAPGSDRILSLKTHLYVGGYDRSTVKVNRDVNITKGFDGCISRLYNFQKPVNLLADIKDAANIQSCGETNMIGGDEDSDNEPPVPPPTPDVHENELQPYAMAPCASDPCENGGSCSEQEDVAVCSCPFGFSGKHCQEHLQLGFNASFRGDGYVELNRSHFQPALEQSYTSMGIVFTTNKPNGLLFWWGQEAGEEYTGQDFIAAAVVDGYVEYSMRLDGEEAVIRNSDIRVDNGERHIVIAKRDENTAILEVDRMLHSGETRPTSKKSMKLPGNVFVGGAPDLEVFTGFRYKHNLNGCIVVVEGETVGQINLSSAAVNGVNANVCPANDDPLGGTEPPVV", "length": 4150, "header": "tr|M9NE61-1|A0ACD4DAU3_DROME Computationally mapped isoform of Terribly reduced optic lobes, isoform BD OS=Drosophila melanogaster OX=7227 GN=trol PE=1 SV=2 CANONICAL=A0ACD4DAU3-1" }, "locus": {} }, { "isoform_ac": "M9NES6-1", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3/entry#M9NES6-1", "sequence": { "sequence": "MMGSPGSQASAIATSVGIRSGRRGQAGGSLLLRLLAVTFVLAACHAPLLTNAKQISNLGDDQDFMLADDESLQGINDSEWQLMGDDIDDGLLDDVDETLKPMETKSEEEDLPTGNWFSQSVHRVRRSINRLFGSDDNQERGRRQQRERSQRNRDAINRQKELRRRQKEDHNRWKQMRMERQLEKQRLVKRTNHVVFNRATDPRKRASDLYDENEASGYHEEDTTLYRTYFVVNEPYDNEYRDRESVQFQNLQKLLDDDLRNFFHSNYEGNDDEEQEIRSTLERVEPTNDNFKIRVQLRIELPTSVNDFGSKLQQQLNVYNRIENLSAATDGVFSFTESSVTEESVRHLDVGFVEPHITLFHEQNTGYDDFDRKPTTETQDIEEEAIDVTLPQEEVEGSGSDDSSCRGDATFTCPRSGKTICDEMRCDREIQCPDGEDEEYCNYPNVCTEDQFKCDDKCLELKKRCDGSIDCLDQTDEAGCINAPEPEPEPEPEPEPEPESEPEAEPEPEPEPEPESEPEQEPEPQVPEANECQANEFRCNNGDCIDARKRCNNVSDCSEGEDENEECPAACSGMEYQCRDGTRCISVSQQCDGHSDCSDGDDEEHCDGSGYDSEECRFDEFHCGTGECIPMRQVCDNIYDCNDYSDEVNCVEGEEEDRVGIPIGHQPWRPASKHDDWLHEMDTSEYQVYQPSNVYEKANSQNPCASNQFRCTTSNVCIPLHLRCDGFYHCNDMSDEKSCEQYQRHTTTRRPLTLATPTSRITTQGPGLLERRNTTTATEASRWPWATKTTTIATTTSNPITTVGVANSPPQTCLENIEFACHNRDCISIESVCDGIPDCGRNEDEDDALCKCSGDKYKCQRGGGCIPKSQVCDGKPQCHDRSDESACHLHGRLNKTRLGVKCLESQYQCGDGSCISGYKRCNGIHDCADASDEYNCIYDYEDTYDTDPNNNPLNECDILEFECDYSQCLPLEKKCDGYADCEDMSDELECQSYTDHCLESEFECDSYCLPRDQLCNGIPNCQDGSDERNCTFCREDAYLCNTGECVADNQRCNGIADCADGSDERHCARIYCPPNKLACNGTCVSRRIKCDGIRDCLDGYDEMYCPETNNHYPTQNVNVIRPKLGPNPIPKSCRPHEWQCANLECIDSSLQCNEIKDCSDGSDEELSVCFGTATTRLKPSDCSPEQFYCDESCYNRSVRCNGHVDCSDGSDEVGCSLPCPQHQCPSGRCYTESERCDRHRHCEDGSDEANCCYANQFRCNNGDCVSGSAPCNGYSECSDHSDELNCGGTQECLPNQFRCNSGQCVSSSVRCNGRTDCQDSSDEQNCAADSNDRRPNQLNLKTYPDSQIIKESREVIFRCRDEGPARAKVKWSRPGGRPLPPGFTDRNGRLEIPNIRVEDAGTYVCEAVGYASYIPGQQVTVNLNVERYNDVGSRPESACTEYQATCMNGECIDKSSICDGNPDCSDASDEQSCSLGLKCQPNQFMCSNSKCVDRTWRCDGENDCGDNSDETSCDPEPSGAPCRYNEFQCRSGHCIPKSFQCDNVPDCTDGTDEVGCMAPLPIRPPPQSVSLLEYEVLELTCVATGTPTPTIVWRLNWGHVPDKCESKSYGGTGTLRCPDMRPQDSGAYSCEIINTRGTHFVNPDTIVTVRPVRTDVCEAGFFNMLARKAEECVQCFCFGVAKACDSANLFTYAIHPPILSHRVVSVELSPLRQIVINEAAPGQDLLTLLHGVQFRATNVHFSGRETPYLALPADYMGNQLKSYGGNLRYEVNYRGSGRPVNGPDVIITGNRFTLTYRVRTQPGQNNRVSIPFVPGGWQKPDGRKASREEIMMILANVDNILIRLGYLDSTAREVDLINIALDSAGTADKGLGSASLVEKCQCPPGYVGDSCESCASGYVRQPGGPWLGHCVPFIPDSCPSGTYGDPRRGVPCKECPCPLTGSNNFASGCQQSPDGDVVCRCNEGYTGRRCEQCAAGYQGNPLAAGGICRRIPDTSCNVDGTYSVHSNGTCQCKDSVIGEQCDTCKSKSFHLNSFTYTGCIECFCSGVGLDCDSSTWYRDQVTSTFGRSRVDHGFVLVTNYMQPTPDTVPVSMAAEPNALSFIGSADQSGNTLYWSLPAAFLGNKLSSYGGKLTYTLSYSPLPNGIMSRNSAPDVVIKSGEDLRLIHYRKSQVVPSVANTYSVEIKESAWQRGDEVVANREHVLMALSDITAIYIKATYTTSTKEASLRQVTLDVATPTNLGTPRAVEVEQCRCPEGYLGLSCEQCAPGYARDPEGGIYLGLCRPCECNGHSKYCNSDTGDCEECSDNTEGPSCERCAAGYVGDATRGTIYDCQPDEGYPIPSPPAPGNQTLECTAYCQIEGIYDCRGNECLCKRNVIGDQCDQCRPGTYGLSAQNQDGCKECYCSGLASQCRSAALYRQLIPVDFILNAPLITDESGAVQDTENLIPDISRNMYTYTHTSYLPKYWSLRGSVLGNQLFSYGGRLSYSLIVESYGNYERGHDIVLIGNGLKLIWSRPDGNENQEEYNVRLHEDEQWTRQDRESARPASRSDFMTVLSDLQHILIRATPRVPTQSTSIGNVILESAVTTRTPGATHASDIELCQCPSGYVGTSCESCAPLHYRDASGSCSLCPCDVSNTESCDLVSGGYVECRCKARWKGDRCREIDTNDPTDIGTEDPVLTQIIVSIQKPEITIVPVGGSMTLSCSGRMRWSNSPVIVNWYKENSRLPENVEVQGGNLYLYDLQVSDSGVYICQAVNNETASVFKDTVSITITKKDQLSPAEIVNLPSHVTFEEYVNNEIICEVLGNPAPRVTWARVDGHADAQSTRTYDNRLIFDSPRKSDEGRYRCQAENDQNRDEKYVIVYVQSNPPQPPPQQDRLYITPEEINGLAGESFQLNCQFTSVASLRYDWSHNGRSLSSSPARNVEIRGNTLEVRDASESDSGVYTCVAYDVRTRRNFTESARVNIDRREEQPFGNKPIIESLEQNILIIQGEDYSITCEASGSPYPSIKWAKVHDFMPENVHISGNVLTIYGARFENRGVYSCVAENDHGSDLSSTSIDIEPRERPSVKIVSAPLQTFSVGAPASLYCTVEGIPDPTVEWVRVDGQPLSPRHKIQSPGYMVIDDIQLEDSGDYECRAKNIVGEATGVATITVQEPTLVQIIPDNRDLRLTEGDELSLTCVGSGVPNPEVEWVNEMALKRDLYSPPSNTAILKIYRVTKADAGIYTCHGKNEAGSDEAHVRVEVQERRGDIGGVDDDSDRDPINYNPPQQQNPGIHQPGSNQLLATDIGDNVTLTCDMFQPLNTRWERVDGAPLPRNAYTIKNRLEIVRVEQQNLGQYRCNGIGRDGNVKTYFVKELVLMPLPRIRFYPNIPLTVEAGQNLDVHCQVENVRPEDVHWSTDNNRPLPSSVRIVGSVLRFVSITQAAAGEYRCSAFNQYGNRSQIARVAVKKPADFHQVPQSQLQRHREGENIQLQCTVTDQYGVRAQDNVEFNWFRDDRRPLPNNARTDSQILVLTNLRPEDAGRYICNSYDVDRGQQLPEVSIDLQVLTATPPPNSPIYLPPQLPAKSRDYSLKLDDQSSNLRAGESTDVECYSSDDTYTDVVWERSDGAPLSNNVRQVGNRLVISNVSPSDAGNYVCKCKTDEGDLYTTSYKLEVEDQPHELKSSKIVYAKVGANADLQCGADESRQPTYRWSRQYGQLQAGRSLMNEKLSLDSVQANDAGTYICTAQYADGETADFPNILVVTGAIPQFRQEPRSYMSFPTLPNSSFKFNFELTFRPENGDGLLLFNGQTRGSGDYIALSLKDRYAEFRFDFGGKPMLVRAEEPLALNEWHTVRVSRFKRDGYIQVDEQHPVAFPTLQQIPQLDLIEDLYIGGVPNWELLPADAVSQQVGFVGCISRLTLQGRTVELIREAKYKEGITDCRPCAQGPCQNKGVCLESQTEQAYTCICQPGWTGRDCAIEGTQCTPGVCGAGRCENTENDMECLCPLNRSGDRCQYNEILNEHSLNFKGNSFAAYGTPKVTKVNITLSVRPASLEDSVILYTAESTLPSGDYLALVLRGGHAELLINTAARLDPVVVRSAEPLPLNRWTRIEIRRRLGEGILRVGDGPERKAKAPGSDRILSLKTHLYVGGYDRSTVKVNRDVNITKGFDGCISRLYNFQKPVNLLADIKDAANIQSCGETNMIGGDEDSDNEPPVPPPTPDVHENELQPYAMAPCASDPCENGGSCSEQEDVAVCSCPFGFSGKHCQEHLQLGFNASFRGDGYVELNRSHFQPALEQSYTSMGIVFTTNKPNGLLFWWGQEAGEEYTGQDFIAAAVVDGYVEYSMRLDGEEAVIRNSDIRVDNGERHIVIAKRDENTAILEVDRMLHSGETRPTSKKSMKLPGNVFVGGAPDLEVFTGFRYKHNLNGCIVVVEGETVGQINLSSAAVNGVNANVCPANDDPLGGTEPPVV", "length": 4451, "header": "tr|M9NES6-1|A0ACD4DAU3_DROME Computationally mapped isoform of Terribly reduced optic lobes, isoform BD OS=Drosophila melanogaster OX=7227 GN=trol PE=1 SV=2 CANONICAL=A0ACD4DAU3-1" }, "locus": {} }, { "isoform_ac": "M9NET2-1", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3/entry#M9NET2-1", "sequence": { "sequence": "MMGSPGSQASAIATSVGIRSGRRGQAGGSLLLRLLAVTFVLAACHAPLLTNAKQISNLGDDQDFMLADDESLQGINDSEWQLMGDDIDDGLLDDVDETLKPMETKSEEEDLPTGNWFSQSVHRVRRSINRLFGSDDNQERGRRQQRERSQRNRDAINRQKELRRRQKEDHNRWKQMRMERQLEKQRLVKRTNHVVFNRATDPRKRASDLYDENEASGYHEEDTTLYRTYFVVNEPYDNEYRDRESVQFQNLQKLLDDDLRNFFHSNYEGNDDEEQEIRSTLERVEPTNDNFKIRVQLRIELPTSVNDFGSKLQQQLNVYNRIENLSAATDGVFSFTESSDIEEEAIDVTLPQEEVEGSGSDDSSCRGDATFTCPRSGKTICDEMRCDREIQCPDGEDEEYCNYPNVCTEDQFKCDDKCLELKKRCDGSIDCLDQTDEAGCINAPEPEPEPEPEPEPEPESEPEAEPEPEPEPEPESEPEQEPEPQVPEANECQANEFRCNNGDCIDARKRCNNVSDCSEGEDENEECRCYANQFRCNNGDCVSGSAPCNGYSECSDHSDELNCGGTQECLPNQFRCNSGQCVSSSVRCNGRTDCQDSSDEQNCAADSNDRRPNQLNLKTYPDSQIIKESREVIFRCRDEGPARAKVKWSRPGGRPLPPGFTDRNGRLEIPNIRVEDAGTYVCEAVGYASYIPGQQVTVNLNVERSWGENKYEEIRSNRIRYGTVPHIDLEFFGLDNDVGSRPESACTEYQATCMNGECIDKSSICDGNPDCSDASDEQSCSLGLKCQPNQFMCSNSKCVDRTWRCDGENDCGDNSDETSCDPEPSGAPCRYNEFQCRSGHCIPKSFQCDNVPDCTDGTDEVGCMAPLPIRPPPQSVSLLEYEVLELTCVATGTPTPTIVWRLNWGHVPDKCESKSYGGTGTLRCPDMRPQDSGAYSCEIINTRGTHFVNPDTIVTVRPVRTDVCEAGFFNMLARKAEECVQCFCFGVAKACDSANLFTYAIHPPILSHRVVSVELSPLRQIVINEAAPGQDLLTLLHGVQFRATNVHFSGRETPYLALPADYMGNQLKSYGGNLRYEVNYRGSGRPVNGPDVIITGNRFTLTYRVRTQPGQNNRVSIPFVPGGWQKPDGRKASREEIMMILANVDNILIRLGYLDSTAREVDLINIALDSAGTADKGLGSASLVEKCQCPPGYVGDSCESCASGYVRQPGGPWLGHCVPFIPDSCPSGTYGDPRRGVPCKECPCPLTGSNNFASGCQQSPDGDVVCRCNEGYTGRRCEQCAAGYQGNPLAAGGICRRIPDTSCNVDGTYSVHSNGTCQCKDSVIGEQCDTCKSKSFHLNSFTYTGCIECFCSGVGLDCDSSTWYRDQVTSTFGRSRVDHGFVLVTNYMQPTPDTVPVSMAAEPNALSFIGSADQSGNTLYWSLPAAFLGNKLSSYGGKLTYTLSYSPLPNGIMSRNSAPDVVIKSGEDLRLIHYRKSQVVPSVANTYSVEIKESAWQRGDEVVANREHVLMALSDITAIYIKATYTTSTKEASLRQVTLDVATPTNLGTPRAVEVEQCRCPEGYLGLSCEQCAPGYARDPEGGIYLGLCRPCECNGHSKYCNSDTGDCEECSDNTEGPSCERCAAGYVGDATRGTIYDCQPDEGYPIPSPPAPGNQTLECTAYCQIEGIYDCRGNECLCKRNVIGDQCDQCRPGTYGLSAQNQDGCKECYCSGLASQCRSAALYRQLIPVDFILNAPLITDESGAVQDTENLIPDISRNMYTYTHTSYLPKYWSLRGSVLGNQLFSYGGRLSYSLIVESYGNYERGHDIVLIGNGLKLIWSRPDGNENQEEYNVRLHEDEQWTRQDRESARPASRSDFMTVLSDLQHILIRATPRVPTQSTSIGNVILESAVTTRTPGATHASDIELCQCPSGYVGTSCESCAPLHYRDASGSCSLCPCDVSNTESCDLVSGGYVECRCKARWKGDRCREIDTNDPTDIGTEDPVLTQIIVSIQKPEITIVPVGGSMTLSCSGRMRWSNSPVIVNWYKENSRLPENVEVQGGNLYLYDLQVSDSGVYICQAVNNETASVFKDTVSITITKKDQLSPAEIVNLPSHVTFEEYVNNEIICEVLGNPAPRVTWARVDGHADAQSTRTYDNRLIFDSPRKSDEGRYRCQAENDQNRDEKYVIVYVQSNPPQPPPQQDRLYITPEEINGLAGESFQLNCQFTSVASLRYDWSHNGRSLSSSPARNVEIRGNTLEVRDASESDSGVYTCVAYDVRTRRNFTESARVNIDRREEQPFGNKPIIESLEQNILIIQGEDYSITCEASGSPYPSIKWAKVHDFMPENVHISGNVLTIYGARFENRGVYSCVAENDHGSDLSSTSIDIEPRERPSVKIVSAPLQTFSVGAPASLYCTVEGIPDPTVEWVRVDGQPLSPRHKIQSPGYMVIDDIQLEDSGDYECRAKNIVGEATGVATITVQEPTLVQIIPDNRDLRLTEGDELSLTCVGSGVPNPEVEWVNEMALKRDLYSPPSNTAILKIYRVTKADAGIYTCHGKNEAGSDEAHVRVEVQERRGDIGGVDDDSDRDPINYNPPQQQNPGIHQPGSNQLLATDIGDNVTLTCDMFQPLNTRWERVDGAPLPRNAYTIKNRLEIVRVEQQNLGQYRCNGIGRDGNVKTYFVKELVLMPLPRIRFYPNIPLTVEAGQNLDVHCQVENVRPEDVHWSTDNNRPLPSSVRIVGSVLRFVSITQAAAGEYRCSAFNQYGNRSQIARVAVKKPADFHQVPQSQLQRHREGENIQLQCTVTDQYGVRAQDNVEFNWFRDDRRPLPNNARTDSQILVLTNLRPEDAGRYICNSYDVDRGQQLPEVSIDLQVLRAPQYPYNRFKGGVSLKDTPCMVLYICADFKSSKLSSAKPIISGPATTRAPAISYVCQPNDFKCVSHPHTCVRANMVCDGIYDCTDHSDEFNCIAGKGSGKSESNSGSGSFKRWKKSPEQGRRSLAKAVKNRKLRKRSFAATPPPNSPIYLPPQLPAKSRDYSLKLDDQSSNLRAGESTDVECYSSDDTYTDVVWERSDGAPLSNNVRQVGNRLVISNVSPSDAGNYVCKCKTDEGDLYTTSYKLEVEDQPHELKSSKIVYAKVGANADLQCGADESRQPTYRWSRQYGQLQAGRSLMNEKLSLDSVQANDAGTYICTAQYADGETADFPNILVVTGAIPQFRQEPRSYMSFPTLPNSSFKFNFELTFRPENGDGLLLFNGQTRGSGDYIALSLKDRYAEFRFDFGGKPMLVRAEEPLALNEWHTVRVSRFKRDGYIQVDEQHPVAFPTLQQIPQLDLIEDLYIGGVPNWELLPADAVSQQVGFVGCISRLTLQGRTVELIREAKYKEGITDCRPCAQGPCQNKGVCLESQTEQAYTCICQPGWTGRDCAIEGTQCTPGVCGAGRCENTENDMECLCPLNRSGDRCQYNEILNEHSLNFKGNSFAAYGTPKVTKVNITLSVRPASLEDSVILYTAESTLPSGDYLALVLRGGHAELLINTAARLDPVVVRSAEPLPLNRWTRIEIRRRLGEGILRVGDGPERKAKAPGSDRILSLKTHLYVGGYDRSTVKVNRDVNITKGFDGCISRLYNFQKPVNLLADIKDAANIQSCGETNMIGGDEDSDNEPPVPPPTPDVHENELQPYAMAPCASDPCENGGSCSEQEDVAVCSCPFGFSGKHCQEHLQLGFNASFRGDGYVELNRSHFQPALEQSYTSMGIVFTTNKPNGLLFWWGQEAGEEYTGQDFIAAAVVDGYVEYSMRLDGEEAVIRNSDIRVDNGERHIVIAKRDENTAILEVDRMLHSGETRPTSKKSMKLPGNVFVGGAPDLEVFTGFRYKHNLNGCIVVVEGETVGQINLSSAAVNGVNANVCPANDDPLGGTEPPVV", "length": 3897, "header": "tr|M9NET2-1|A0ACD4DAU3_DROME Computationally mapped isoform of Terribly reduced optic lobes, isoform BD OS=Drosophila melanogaster OX=7227 GN=trol PE=1 SV=2 CANONICAL=A0ACD4DAU3-1" }, "locus": {} }, { "isoform_ac": "M9NFR6-1", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3/entry#M9NFR6-1", "sequence": { "sequence": "MMGSPGSQASAIATSVGIRSGRRGQAGGSLLLRLLAVTFVLAACHAPLLTNAKQISNLGDDQDFMLADDESLQGINDSEWQLMGDDIDDGLLDDVDETLKPMETKSEEEDLPTGNWFSQSVHRVRRSINRLFGSDDNQERGRRQQRERSQRNRDAINRQKELRRRQKEDHNRWKQMRMERQLEKQRLVKRTNHVVFNRATDPRKRASDLYDENEASGYHEEDTTLYRTYFVVNEPYDNEYRDRESVQFQNLQKLLDDDLRNFFHSNYEGNDDEEQEIRSTLERVEIELPTSVNDFGSKLQQQLNVYNRIENLSAATDGVFSFTESSVTEESVRHLDVGFVEPHITLFHEQNTGYDDFDRKPTTETQDIEEEAIDVTLPQEEVEGSGSDDSSCRGDATFTCPRSGKTICDEMRCDREIQCPDGEDEEYCNYPNVCTEDQFKCDDKCLELKKRCDGSIDCLDQTDEAGCINAPEPEPEPEPEPEPEPESEPEAEPEPEPEPEPESEPEQEPEPQVPEANECQANEFRCNNGDCIDARKRCNNVSDCSEGEDENEECPTTRLKPSDCSPEQFYCDESCYNRSVRCNGHVDCSDGSDEVGCSLPCPQHQCPSGRCYTESERCDRHRHCEDGSDEANCCYANQFRCNNGDCVSGSAPCNGYSECSDHSDELNCGGTQECLPNQFRCNSGQCVSSSVRCNGRTDCQDSSDEQNCAADSNDRRPNQLNLKTYPDSQIIKESREVIFRCRDEGPARAKVKWSRPGGRPLPPGFTDRNGRLEIPNIRVEDAGTYVCEAVGYASYIPGQQVTVNLNVERYNDVGSRPESACTEYQATCMNGECIDKSSICDGNPDCSDASDEQSCSLGLKCQPNQFMCSNSKCVDRTWRCDGENDCGDNSDETSCDPEPSGAPCRYNEFQCRSGHCIPKSFQCDNVPDCTDGTDEVGCMAPLPIRPPPQSVSLLEYEVLELTCVATGTPTPTIVWRLNWGHVPDKCESKSYGGTGTLRCPDMRPQDSGAYSCEIINTRGTHFVNPDTIVTVRPVRTDVCEAGFFNMLARKAEECVQCFCFGVAKACDSANLFTYAIHPPILSHRVVSVELSPLRQIVINEAAPGQDLLTLLHGVQFRATNVHFSGRETPYLALPADYMGNQLKSYGGNLRYEVNYRGSGRPVNGPDVIITGNRFTLTYRVRTQPGQNNRVSIPFVPGGWQKPDGRKASREEIMMILANVDNILIRLGYLDSTAREVDLINIALDSAGTADKGLGSASLVEKCQCPPGYVGDSCESCASGYVRQPGGPWLGHCVPFIPDSCPSGTYGDPRRGVPCKECPCPLTGSNNFASGCQQSPDGDVVCRCNEGYTGRRCEQCAAGYQGNPLAAGGICRRIPDTSCNVDGTYSVHSNGTCQCKDSVIGEQCDTCKSKSFHLNSFTYTGCIECFCSGVGLDCDSSTWYRDQVTSTFGRSRVDHGFVLVTNYMQPTPDTVPVSMAAEPNALSFIGSADQSGNTLYWSLPAAFLGNKLSSYGGKLTYTLSYSPLPNGIMSRNSAPDVVIKSGEDLRLIHYRKSQVVPSVANTYSVEIKESAWQRGDEVVANREHVLMALSDITAIYIKATYTTSTKEASLRQVTLDVATPTNLGTPRAVEVEQCRCPEGYLGLSCEQCAPGYARDPEGGIYLGLCRPCECNGHSKYCNSDTGDCEECSDNTEGPSCERCAAGYVGDATRGTIYDCQPDEGYPIPSPPAPGNQTLECTAYCQIEGIYDCRGNECLCKRNVIGDQCDQCRPGTYGLSAQNQDGCKECYCSGLASQCRSAALYRQLIPVDFILNAPLITDESGAVQDTENLIPDISRNMYTYTHTSYLPKYWSLRGSVLGNQLFSYGGRLSYSLIVESYGNYERGHDIVLIGNGLKLIWSRPDGNENQEEYNVRLHEDEQWTRQDRESARPASRSDFMTVLSDLQHILIRATPRVPTQSTSIGNVILESAVTTRTPGATHASDIELCQCPSGYVGTSCESCAPLHYRDASGSCSLCPCDVSNTESCDLVSGGYVECRCKARWKGDRCREIDTNDPTDIGTEDPVLTQIIVSIQKPEITIVPVGGSMTLSCSGRMRWSNSPVIVNWYKENSRLPENVEVQGGNLYLYDLQVSDSGVYICQAVNNETASVFKDTVSITITKKDQLSPAEIVNLPSHVTFEEYVNNEIICEVLGNPAPRVTWARVDGHADAQSTRTYDNRLIFDSPRKSDEGRYRCQAENDQNRDEKYVIVYVQSNPPQPPPQQDRLYITPEEINGLAGESFQLNCQFTSVASLRYDWSHNGRSLSSSPARNVEIRGNTLEVRDASESDSGVYTCVAYDVRTRRNFTESARVNIDRREEQPFGNKPIIESLEQNILIIQGEDYSITCEASGSPYPSIKWAKVHDFMPENVHISGNVLTIYGARFENRGVYSCVAENDHGSDLSSTSIDIEPRERPSVKIVSAPLQTFSVGAPASLYCTVEGIPDPTVEWVRVDGQPLSPRHKIQSPGYMVIDDIQLEDSGDYECRAKNIVGEATGVATITVQEPTLVQIIPDNRDLRLTEGDELSLTCVGSGVPNPEVEWVNEMALKRDLYSPPSNTAILKIYRVTKADAGIYTCHGKNEAGSDEAHVRVEVQERRGDIGGVDDDSDRDPINYNPPQQQNPGIHQPGSNQLLATDIGDNVTLTCDMFQPLNTRWERVDGAPLPRNAYTIKNRLEIVRVEQQNLGQYRCNGIGRDGNVKTYFVKELVLMPLPRIRFYPNIPLTVEAGQNLDVHCQVENVRPEDVHWSTDNNRPLPSSVRIVGSVLRFVSITQAAAGEYRCSAFNQYGNRSQIARVAVKKPADFHQVPQSQLQRHREGENIQLQCTVTDQYGVRAQDNVEFNWFRDDRRPLPNNARTDSQILVLTNLRPEDAGRYICNSYDVDRGQQLPEVSIDLQVLTATPPPNSPIYLPPQLPAKSRDYSLKLDDQSSNLRAGESTDVECYSSDDTYTDVVWERSDGAPLSNNVRQVGNRLVISNVSPSDAGNYVCKCKTDEGDLYTTSYKLEVEDQPHELKSSKIVYAKVGANADLQCGADESRQPTYRWSRQYGQLQAGRSLMNEKLSLDSVQANDAGTYICTAQYADGETADFPNILVVTGAIPQFRQEPRSYMSFPTLPNSSFKFNFELTFRPENGDGLLLFNGQTRGSGDYIALSLKDRYAEFRFDFGGKPMLVRAEEPLALNEWHTVRVSRFKRDGYIQVDEQHPVAFPTLQQIPQLDLIEDLYIGGVPNWELLPADAVSQQVGFVGCISRLTLQGRTVELIREAKYKEGITDCRPCAQGPCQNKGVCLESQTEQAYTCICQPGWTGRDCAIEGTQCTPGVCGAGRCENTENDMECLCPLNRSGDRCQYNEILNEHSLNFKGNSFAAYGTPKVTKVNITLSVRPASLEDSVILYTAESTLPSGDYLALVLRGGHAELLINTAARLDPVVVRSAEPLPLNRWTRIEIRRRLGEGILRVGDGPERKAKAPGSDRILSLKTHLYVGGYDRSTVKVNRDVNITKGFDGCISRLYNFQKPVNLLADIKDAANIQSCGETNMIGGDEDSDNEPPVPPPTPDVHENELQPYAMAPCASDPCENGGSCSEQEDVAVCSCPFGFSGKHCQEHLQLGFNASFRGDGYVELNRSHFQPALEQSYTSMGIVFTTNKPNGLLFWWGQEAGEEYTGQDFIAAAVVDGYVEYSMRLDGEEAVIRNSDIRVDNGERHIVIAKRDENTAILEVDRMLHSGETRPTSKKSMKLPGNVFVGGAPDLEVFTGFRYKHNLNGCIVVVEGETVGQINLSSAAVNGVNANVCPANDDPLGGTEPPVV", "length": 3833, "header": "tr|M9NFR6-1|A0ACD4DAU3_DROME Computationally mapped isoform of Terribly reduced optic lobes, isoform BD OS=Drosophila melanogaster OX=7227 GN=trol PE=1 SV=2 CANONICAL=A0ACD4DAU3-1" }, "locus": {} }, { "isoform_ac": "M9NFS1-1", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3/entry#M9NFS1-1", "sequence": { "sequence": "MMGSPGSQASAIATSVGIRSGRRGQAGGSLLLRLLAVTFVLAACHAPLLTNAKQISNLGDDQDFMLADDESLQGINDSEWQLMGDDIDDGLLDDVDETLKPMETKSEEEDLPTGNWFSQSVHRVRRSINRLFGSDDNQERGRRQQRERSQRNRDAINRQKELRRRQKEDHNRWKQMRMERQLEKQRLVKRTNHVVFNRATDPRKRASDLYDENEASGYHEEDTTLYRTYFVVNEPYDNEYRDRESVQFQNLQKLLDDDLRNFFHSNYEGNDDEEQEIRSTLERVEPTNDNFKIRVQLRIELPTSVNDFGSKLQQQLNVYNRIENLSAATDGVFSFTESSDIEEEAIDVTLPQEEVEGSGSDDSSCRGDATFTCPRSGKTICDEMRCDREIQCPDGEDEEYCNYPNVCTEDQFKCDDKCLELKKRCDGSIDCLDQTDEAGCINAPEPEPEPEPEPEPEPESEPEAEPEPEPEPEPESEPEQEPEPQVPEANECQANEFRCNNGDCIDARKRCNNVSDCSEGEDENEECPAACSGMEYQCRDGTRCISVSQQCDGHSDCSDGDDEEHCDGSGYDSEECRFDEFHCGTGECIPMRQVCDNIYDCNDYSDEVNCVEGEEEDRVGIPIGHQPWRPASKHDDWLHEMDTSEYQVYQPSNVYEKANSQNPCASNQFRCTTSNVCIPLHLRCDGFYHCNDMSDEKSCEQYQRHTTTRRPLTLATPTSRITTQGPGLLERRNTTTATEASRWPWATKTTTIATTTSNPITTVGVANSPPQTCLENIEFACHNRDCISIESVCDGIPDCGRNEDEDDALCKCSGDKYKCQRGGGCIPKSQVCDGKPQCHDRSDESACHLHGRLNKTRLGVKCLESQYQCGDGSCISGYKRCNGIHDCADASDEYNCIYDYEDTYDTDPNNNPLNECDILEFECDYSQCLPLEKKCDGYADCEDMSDELECQSYTETNNHYPTQNVNVIRPKLGPNPIPKSCRPHEWQCANLECIDSSLQCNEIKDCSDGSDEELSVCFGTATTRLKPSDCSPEQFYCDESCYNRSVRCNGHVDCSDGSDEVGCSLPCPQHQCPSGRCYTESERCDRHRHCEDGSDEANCCYANQFRCNNGDCVSGSAPCNGYSECSDHSDELNCGGTQECLPNQFRCNSGQCVSSSVRCNGRTDCQDSSDEQNCAADSNDRRPNQLNLKTYPDSQIIKESREVIFRCRDEGPARAKVKWSRPGGRPLPPGFTDRNGRLEIPNIRVEDAGTYVCEAVGYASYIPGQQVTVNLNVERYNDVGSRPESACTEYQATCMNGECIDKSSICDGNPDCSDASDEQSCSLGLKCQPNQFMCSNSKCVDRTWRCDGENDCGDNSDETSCDPEPSGAPCRYNEFQCRSGHCIPKSFQCDNVPDCTDGTDEVGCMAPLPIRPPPQSVSLLEYEVLELTCVATGTPTPTIVWRLNWGHVPDKCESKSYGGTGTLRCPDMRPQDSGAYSCEIINTRGTHFVNPDTIVTVRPVRTDVCEAGFFNMLARKAEECVQCFCFGVAKACDSANLFTYAIHPPILSHRVVSVELSPLRQIVINEAAPGQDLLTLLHGVQFRATNVHFSGRETPYLALPADYMGNQLKSYGGNLRYEVNYRGSGRPVNGPDVIITGNRFTLTYRVRTQPGQNNRVSIPFVPGGWQKPDGRKASREEIMMILANVDNILIRLGYLDSTAREVDLINIALDSAGTADKGLGSASLVEKCQCPPGYVGDSCESCASGYVRQPGGPWLGHCVPFIPDSCPSGTYGDPRRGVPCKECPCPLTGSNNFASGCQQSPDGDVVCRCNEGYTGRRCEQCAAGYQGNPLAAGGICRRIPDTSCNVDGTYSVHSNGTCQCKDSVIGEQCDTCKSKSFHLNSFTYTGCIECFCSGVGLDCDSSTWYRDQVTSTFGRSRVDHGFVLVTNYMQPTPDTVPVSMAAEPNALSFIGSADQSGNTLYWSLPAAFLGNKLSSYGGKLTYTLSYSPLPNGIMSRNSAPDVVIKSGEDLRLIHYRKSQVVPSVANTYSVEIKESAWQRGDEVVANREHVLMALSDITAIYIKATYTTSTKEASLRQVTLDVATPTNLGTPRAVEVEQCRCPEGYLGLSCEQCAPGYARDPEGGIYLGLCRPCECNGHSKYCNSDTGDCEECSDNTEGPSCERCAAGYVGDATRGTIYDCQPDEGYPIPSPPAPGNQTLECTAYCQIEGIYDCRGNECLCKRNVIGDQCDQCRPGTYGLSAQNQDGCKECYCSGLASQCRSAALYRQLIPVDFILNAPLITDESGAVQDTENLIPDISRNMYTYTHTSYLPKYWSLRGSVLGNQLFSYGGRLSYSLIVESYGNYERGHDIVLIGNGLKLIWSRPDGNENQEEYNVRLHEDEQWTRQDRESARPASRSDFMTVLSDLQHILIRATPRVPTQSTSIGNVILESAVTTRTPGATHASDIELCQCPSGYVGTSCESCAPLHYRDASGSCSLCPCDVSNTESCDLVSGGYVECRCKARWKGDRCREIDTNDPTDIGTEDPVLTQIIVSIQKPEITIVPVGGSMTLSCSGRMRWSNSPVIVNWYKENSRLPENVEVQGGNLYLYDLQVSDSGVYICQAVNNETASVFKDTVSITITKKDQLSPAEIVNLPSHVTFEEYVNNEIICEVLGNPAPRVTWARVDGHADAQSTRTYDNRLIFDSPRKSDEGRYRCQAENDQNRDEKYVIVYVQSNPPQPPPQQDRLYITPEEINGLAGESFQLNCQFTSVASLRYDWSHNGRSLSSSPARNVEIRGNTLEVRDASESDSGVYTCVAYDVRTRRNFTESARVNIDRREEQPFGNKPIIESLEQNILIIQGEDYSITCEASGSPYPSIKWAKVHDFMPENVHISGNVLTIYGARFENRGVYSCVAENDHGSDLSSTSIDIEPRERPSVKIVSAPLQTFSVGAPASLYCTVEGIPDPTVEWVRVDGQPLSPRHKIQSPGYMVIDDIQLEDSGDYECRAKNIVGEATGVATITVQEPTLVQIIPDNRDLRLTEGDELSLTCVGSGVPNPEVEWVNEMALKRDLYSPPSNTAILKIYRVTKADAGIYTCHGKNEAGSDEAHVRVEVQERRGDIGGVDDDSDRDPINYNPPQQQNPGIHQPGSNQLLATDIGDNVTLTCDMFQPLNTRWERVDGAPLPRNAYTIKNRLEIVRVEQQNLGQYRCNGIGRDGNVKTYFVKELVLMPLPRIRFYPNIPLTVEAGQNLDVHCQVENVRPEDVHWSTDNNRPLPSSVRIVGSVLRFVSITQAAAGEYRCSAFNQYGNRSQIARVAVKKPADFHQVPQSQLQRHREGENIQLQCTVTDQYGVRAQDNVEFNWFRDDRRPLPNNARTDSQILVLTNLRPEDAGRYICNSYDVDRGQQLPEVSIDLQVLTATPPPNSPIYLPPQLPAKSRDYSLKLDDQSSNLRAGESTDVECYSSDDTYTDVVWERSDGAPLSNNVRQVGNRLVISNVSPSDAGNYVCKCKTDEGDLYTTSYKLEVEDQPHELKSSKIVYAKVGANADLQCGADESRQPTYRWSRQYGQLQAGRSLMNEKLSLDSVQANDAGTYICTAQYADGETADFPNILVVTGAIPQFRQEPRSYMSFPTLPNSSFKFNFELTFRPENGDGLLLFNGQTRGSGDYIALSLKDRYAEFRFDFGGKPMLVRAEEPLALNEWHTVRVSRFKRDGYIQVDEQHPVAFPTLQQIPQLDLIEDLYIGGVPNWELLPADAVSQQVGFVGCISRLTLQGRTVELIREAKYKEGITDCRPCAQGPCQNKGVCLESQTEQAYTCICQPGWTGRDCAIEGTQCTPGVCGAGRCENTENDMECLCPLNRSGDRCQYNEILNEHSLNFKGNSFAAYGTPKVTKVNITLSVRPASLEDSVILYTAESTLPSGDYLALVLRGGHAELLINTAARLDPVVVRSAEPLPLNRWTRIEIRRRLGEGILRVGDGPERKAKAPGSDRILSLKTHLYVGGYDRSTVKVNRDVNITKGFDGCISRLYNFQKPVNLLADIKDAANIQSCGETNMIGGDEDSDNEPPVPPPTPDVHENELQPYAMAPCASDPCENGGSCSEQEDVAVCSCPFGFSGKHCQEHLQLGFNASFRGDGYVELNRSHFQPALEQSYTSMGIVFTTNKPNGLLFWWGQEAGEEYTGQDFIAAAVVDGYVEYSMRLDGEEAVIRNSDIRVDNGERHIVIAKRDENTAILEVDRMLHSGETRPTSKKSMKLPGNVFVGGAPDLEVFTGFRYKHNLNGCIVVVEGETVGQINLSSAAVNGVNANVCPANDDPLGGTEPPVV", "length": 4299, "header": "tr|M9NFS1-1|A0ACD4DAU3_DROME Computationally mapped isoform of Terribly reduced optic lobes, isoform BD OS=Drosophila melanogaster OX=7227 GN=trol PE=1 SV=2 CANONICAL=A0ACD4DAU3-1" }, "locus": {} }, { "isoform_ac": "M9NGK3-1", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3/entry#M9NGK3-1", "sequence": { "sequence": "MMGSPGSQASAIATSVGIRSGRRGQAGGSLLLRLLAVTFVLAACHAPLLTNAKQISNLGDDQDFMLADDESLQGINDSEWQLMGDDIDDGLLDDVDETLKPMETKSEEEDLPTGNWFSQSVHRVRRSINRLFGSDDNQERGRRQQRERSQRNRDAINRQKELRRRQKEDHNRWKQMRMERQLEKQRLVKRTNHVVFNRATDPRKRASDLYDENEASGYHEEDTTLYRTYFVVNEPYDNEYRDRESVQFQNLQKLLDDDLRNFFHSNYEGNDDEEQEIRSTLERVEPTNDNFKIRVQLRIELPTSVNDFGSKLQQQLNVYNRIENLSAATDGVFSFTESSDIEEEAIDVTLPQEEVEGSGSDDSSCRGDATFTCPRSGKTICDEMRCDREIQCPDGEDEEYCNYPNVCTEDQFKCDDKCLELKKRCDGSIDCLDQTDEAGCINAPEPEPEPEPEPEPEPESEPEAEPEPEPEPEPESEPEQEPEPQVPEANECQANEFRCNNGDCIDARKRCNNVSDCSEGEDENEECRCYANQFRCNNGDCVSGSAPCNGYSECSDHSDELNCGGTQECLPNQFRCNSGQCVSSSVRCNGRTDCQDSSDEQNCAADSNDRRPNQLNLKTYPDSQIIKESREVIFRCRDEGPARAKVKWSRPGGRPLPPGFTDRNGRLEIPNIRVEDAGTYVCEAVGYASYIPGQQVTVNLNVERYNDVGSRPESACTEYQATCMNGECIDKSSICDGNPDCSDASDEQSCSLGLKCQPNQFMCSNSKCVDRTWRCDGENDCGDNSDETSCDPEPSGAPCRYNEFQCRSGHCIPKSFQCDNVPDCTDGTDEVGCMAPLPIRPPPQSVSLLEYEVLELTCVATGTPTPTIVWRLNWGHVPDKCESKSYGGTGTLRCPDMRPQDSGAYSCEIINTRGTHFVNPDTIVTVRPVRTDVCEAGFFNMLARKAEECVQCFCFGVAKACDSANLFTYAIHPPILSHRVVSVELSPLRQIVINEAAPGQDLLTLLHGVQFRATNVHFSGRETPYLALPADYMGNQLKSYGGNLRYEVNYRGSGRPVNGPDVIITGNRFTLTYRVRTQPGQNNRVSIPFVPGGWQKPDGRKASREEIMMILANVDNILIRLGYLDSTAREVDLINIALDSAGTADKGLGSASLVEKCQCPPGYVGDSCESCASGYVRQPGGPWLGHCVPFIPDSCPSGTYGDPRRGVPCKECPCPLTGSNNFASGCQQSPDGDVVCRCNEGYTGRRCEQCAAGYQGNPLAAGGICRRIPDTSCNVDGTYSVHSNGTCQCKDSVIGEQCDTCKSKSFHLNSFTYTGCIECFCSGVGLDCDSSTWYRDQVTSTFGRSRVDHGFVLVTNYMQPTPDTVPVSMAAEPNALSFIGSADQSGNTLYWSLPAAFLGNKLSSYGGKLTYTLSYSPLPNGIMSRNSAPDVVIKSGEDLRLIHYRKSQVVPSVANTYSVEIKESAWQRGDEVVANREHVLMALSDITAIYIKATYTTSTKEASLRQVTLDVATPTNLGTPRAVEVEQCRCPEGYLGLSCEQCAPGYARDPEGGIYLGLCRPCECNGHSKYCNSDTGDCEECSDNTEGPSCERCAAGYVGDATRGTIYDCQPDEGYPIPSPPAPGNQTLECTAYCQIEGIYDCRGNECLCKRNVIGDQCDQCRPGTYGLSAQNQDGCKECYCSGLASQCRSAALYRQLIPVDFILNAPLITDESGAVQDTENLIPDISRNMYTYTHTSYLPKYWSLRGSVLGNQLFSYGGRLSYSLIVESYGNYERGHDIVLIGNGLKLIWSRPDGNENQEEYNVRLHEDEQWTRQDRESARPASRSDFMTVLSDLQHILIRATPRVPTQSTSIGNVILESAVTTRTPGATHASDIELCQCPSGYVGTSCESCAPLHYRDASGSCSLCPCDVSNTESCDLVSGGYVECRCKARWKGDRCREIDTNDPTDIGTEDPVLTQIIVSIQKPEITIVPVGGSMTLSCSGRMRWSNSPVIVNWYKENSRLPENVEVQGGNLYLYDLQVSDSGVYICQAVNNETASVFKDTVSITITKKDQLSPAEIVNLPSHVTFEEYVNNEIICEVLGNPAPRVTWARVDGHADAQSTRTYDNRLIFDSPRKSDEGRYRCQAENDQNRDEKYVIVYVQSNPPQPPPQQDRLYITPEEINGLAGESFQLNCQFTSVASLRYDWSHNGRSLSSSPARNVEIRGNTLEVRDASESDSGVYTCVAYDVRTRRNFTESARVNIDRREEQPFGNKPIIESLEQNILIIQGEDYSITCEASGSPYPSIKWAKVHDFMPENVHISGNVLTIYGARFENRGVYSCVAENDHGSDLSSTSIDIEPRERPSVKIVSAPLQTFSVGAPASLYCTVEGIPDPTVEWVRVDGQPLSPRHKIQSPGYMVIDDIQLEDSGDYECRAKNIVGEATGVATITVQEPTLVQIIPDNRDLRLTEGDELSLTCVGSGVPNPEVEWVNEMALKRDLYSPPSNTAILKIYRVTKADAGIYTCHGKNEAGSDEAHVRVEVQERRGDIGGVDDDSDRDPINYNPPQQQNPGIHQPGSNQLLATDIGDNVTLTCDMFQPLNTRWERVDGAPLPRNAYTIKNRLEIVRVEQQNLGQYRCNGIGRDGNVKTYFVKELVLMPLPRIRFYPNIPLTVEAGQNLDVHCQVENVRPEDVHWSTDNNRPLPSSVRIVGSVLRFVSITQAAAGEYRCSAFNQYGNRSQIARVAVKKPADFHQVPQSQLQRHREGENIQLQCTVTDQYGVRAQDNVEFNWFRDDRRPLPNNARTDSQILVLTNLRPEDAGRYICNSYDVDRGQQLPEVSIDLQVLTATPPPNSPIYLPPQLPAKSRDYSLKLDDQSSNLRAGESTDVECYSSDDTYTDVVWERSDGAPLSNNVRQVGNRLVISNVSPSDAGNYVCKCKTDEGDLYTTSYKLEVEDQPHELKSSKIVYAKVGANADLQCGADESRQPTYRWSRQYGQLQAGRSLMNEKLSLDSVQANDAGTYICTAQYADGETADFPNILVVTGAIPQFRQEPRSYMSFPTLPNSSFKFNFELTFRPENGDGLLLFNGQTRGSGDYIALSLKDRYAEFRFDFGGKPMLVRAEEPLALNEWHTVRVSRFKRDGYIQVDEQHPVAFPTLQQIPQLDLIEDLYIGGVPNWELLPADAVSQQVGFVGCISRLTLQGRTVELIREAKYKEGITDCRPCAQGPCQNKGVCLESQTEQAYTCICQPGWTGRDCAIEGTQCTPGVCGAGRCENTENDMECLCPLNRSGDRCQYNEILNEHSLNFKGNSFAAYGTPKVTKVNITLSVRPASLEDSVILYTAESTLPSGDYLALVLRGGHAELLINTAARLDPVVVRSAEPLPLNRWTRIEIRRRLGEGILRVGDGPERKAKAPGSDRILSLKTHLYVGGYDRSTVKVNRDVNITKGFDGCISRLYNFQKPVNLLADIKDAANIQSCGETNMIGGDEDSDNEPPVPPPTPDVHENELQPYAMAPCASDPCENGGSCSEQEDVAVCSCPFGFSGKHCQEHLQLGFNASFRGDGYVELNRSHFQPALEQSYTSMGIVFTTNKPNGLLFWWGQEAGEEYTGQDFIAAAVVDGYVEYSMRLDGEEAVIRNSDIRVDNGERHIVIAKRDENTAILEVDRMLHSGETRPTSKKSMKLPGNVFVGGAPDLEVFTGFRYKHNLNGCIVVVEGETVGQINLSSAAVNGVNANVCPANDDPLGGTEPPVV", "length": 3728, "header": "tr|M9NGK3-1|A0ACD4DAU3_DROME Computationally mapped isoform of Terribly reduced optic lobes, isoform BD OS=Drosophila melanogaster OX=7227 GN=trol PE=1 SV=2 CANONICAL=A0ACD4DAU3-1" }, "locus": {} }, { "isoform_ac": "M9NGL3-1", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3/entry#M9NGL3-1", "sequence": { "sequence": "MMGSPGSQASAIATSVGIRSGRRGQAGGSLLLRLLAVTFVLAACHAPLLTNAKQISNLGDDQDFMLADDESLQGINDSEWQLMGDDIDDGLLDDVDETLKPMETKSEEEDLPTGNWFSQSVHRVRRSINRLFGSDDNQERGRRQQRERSQRNRDAINRQKELRRRQKEDHNRWKQMRMERQLEKQRLVKRTNHVVFNRATDPRKRASDLYDENEASGYHEEDTTLYRTYFVVNEPYDNEYRDRESVQFQNLQKLLDDDLRNFFHSNYEGNDDEEQEIRSTLERVEPTNDNFKIRVQLRIELPTSVNDFGSKLQQQLNVYNRIENLSAATDGVFSFTESSDIEEEAIDVTLPQEEVEGSGSDDSSCRGDATFTCPRSGKTICDEMRCDREIQCPDGEDEEYCNYPNVCTEDQFKCDDKCLELKKRCDGSIDCLDQTDEAGCINAPEPEPEPEPEPEPEPESEPEAEPEPEPEPEPESEPEQEPEPQVPEANECQANEFRCNNGDCIDARKRCNNVSDCSEGEDENEECPAACSGMEYQCRDGTRCISVSQQCDGHSDCSDGDDEEHCDGSGYDSEECRFDEFHCGTGECIPMRQVCDNIYDCNDYSDEVNCVEGEEEDRVGIPIGHQPWRPASKHDDWLHEMDTSEYQVYQPSNVYEKANSQNPCASNQFRCTTSNVCIPLHLRCDGFYHCNDMSDEKSCEQYQRHTTTRRPLTLATPTSRITTQGPGLLERRNTTTATEASRWPWATKTTTIATTTSNPITTVGVASCYANQFRCNNGDCVSGSAPCNGYSECSDHSDELNCGGTQECLPNQFRCNSGQCVSSSVRCNGRTDCQDSSDEQNCAADSNDRRPNQLNLKTYPDSQIIKESREVIFRCRDEGPARAKVKWSRPGGRPLPPGFTDRNGRLEIPNIRVEDAGTYVCEAVGYASYIPGQQVTVNLNVERYNDVGSRPESACTEYQATCMNGECIDKSSICDGNPDCSDASDEQSCSLGLKCQPNQFMCSNSKCVDRTWRCDGENDCGDNSDETSCDPEPSGAPCRYNEFQCRSGHCIPKSFQCDNVPDCTDGTDEVGCMAPLPIRPPPQSVSLLEYEVLELTCVATGTPTPTIVWRLNWGHVPDKCESKSYGGTGTLRCPDMRPQDSGAYSCEIINTRGTHFVNPDTIVTVRPVRTDVCEAGFFNMLARKAEECVQCFCFGVAKACDSANLFTYAIHPPILSHRVVSVELSPLRQIVINEAAPGQDLLTLLHGVQFRATNVHFSGRETPYLALPADYMGNQLKSYGGNLRYEVNYRGSGRPVNGPDVIITGNRFTLTYRVRTQPGQNNRVSIPFVPGGWQKPDGRKASREEIMMILANVDNILIRLGYLDSTAREVDLINIALDSAGTADKGLGSASLVEKCQCPPGYVGDSCESCASGYVRQPGGPWLGHCVPFIPDSCPSGTYGDPRRGVPCKECPCPLTGSNNFASGCQQSPDGDVVCRCNEGYTGRRCEQCAAGYQGNPLAAGGICRRIPDTSCNVDGTYSVHSNGTCQCKDSVIGEQCDTCKSKSFHLNSFTYTGCIECFCSGVGLDCDSSTWYRDQVTSTFGRSRVDHGFVLVTNYMQPTPDTVPVSMAAEPNALSFIGSADQSGNTLYWSLPAAFLGNKLSSYGGKLTYTLSYSPLPNGIMSRNSAPDVVIKSGEDLRLIHYRKSQVVPSVANTYSVEIKESAWQRGDEVVANREHVLMALSDITAIYIKATYTTSTKEASLRQVTLDVATPTNLGTPRAVEVEQCRCPEGYLGLSCEQCAPGYARDPEGGIYLGLCRPCECNGHSKYCNSDTGDCEECSDNTEGPSCERCAAGYVGDATRGTIYDCQPDEGYPIPSPPAPGNQTLECTAYCQIEGIYDCRGNECLCKRNVIGDQCDQCRPGTYGLSAQNQDGCKECYCSGLASQCRSAALYRQLIPVDFILNAPLITDESGAVQDTENLIPDISRNMYTYTHTSYLPKYWSLRGSVLGNQLFSYGGRLSYSLIVESYGNYERGHDIVLIGNGLKLIWSRPDGNENQEEYNVRLHEDEQWTRQDRESARPASRSDFMTVLSDLQHILIRATPRVPTQSTSIGNVILESAVTTRTPGATHASDIELCQCPSGYVGTSCESCAPLHYRDASGSCSLCPCDVSNTESCDLVSGGYVECRCKARWKGDRCREIDTNDPTDIGTEDPVLTQIIVSIQKPEITIVPVGGSMTLSCSGRMRWSNSPVIVNWYKENSRLPENVEVQGGNLYLYDLQVSDSGVYICQAVNNETASVFKDTVSITITKKDQLSPAEIVNLPSHVTFEEYVNNEIICEVLGNPAPRVTWARVDGHADAQSTRTYDNRLIFDSPRKSDEGRYRCQAENDQNRDEKYVIVYVQSNPPQPPPQQDRLYITPEEINGLAGESFQLNCQFTSVASLRYDWSHNGRSLSSSPARNVEIRGNTLEVRDASESDSGVYTCVAYDVRTRRNFTESARVNIDRREEQPFGNKPIIESLEQNILIIQGEDYSITCEASGSPYPSIKWAKVHDFMPENVHISGNVLTIYGARFENRGVYSCVAENDHGSDLSSTSIDIEPRERPSVKIVSAPLQTFSVGAPASLYCTVEGIPDPTVEWVRVDGQPLSPRHKIQSPGYMVIDDIQLEDSGDYECRAKNIVGEATGVATITVQEPTLVQIIPDNRDLRLTEGDELSLTCVGSGVPNPEVEWVNEMALKRDLYSPPSNTAILKIYRVTKADAGIYTCHGKNEAGSDEAHVRVEVQERRGDIGGVDDDSDRDPINYNPPQQQNPGIHQPGSNQLLATDIGDNVTLTCDMFQPLNTRWERVDGAPLPRNAYTIKNRLEIVRVEQQNLGQYRCNGIGRDGNVKTYFVKELVLMPLPRIRFYPNIPLTVEAGQNLDVHCQVENVRPEDVHWSTDNNRPLPSSVRIVGSVLRFVSITQAAAGEYRCSAFNQYGNRSQIARVAVKKPADFHQVPQSQLQRHREGENIQLQCTVTDQYGVRAQDNVEFNWFRDDRRPLPNNARTDSQILVLTNLRPEDAGRYICNSYDVDRGQQLPEVSIDLQVLTATPPPNSPIYLPPQLPAKSRDYSLKLDDQSSNLRAGESTDVECYSSDDTYTDVVWERSDGAPLSNNVRQVGNRLVISNVSPSDAGNYVCKCKTDEGDLYTTSYKLEVEDQPHELKSSKIVYAKVGANADLQCGADESRQPTYRWSRQYGQLQAGRSLMNEKLSLDSVQANDAGTYICTAQYADGETADFPNILVVTGAIPQFRQEPRSYMSFPTLPNSSFKFNFELTFRPENGDGLLLFNGQTRGSGDYIALSLKDRYAEFRFDFGGKPMLVRAEEPLALNEWHTVRVSRFKRDGYIQVDEQHPVAFPTLQQIPQLDLIEDLYIGGVPNWELLPADAVSQQVGFVGCISRLTLQGRTVELIREAKYKEGITDCRPCAQGPCQNKGVCLESQTEQAYTCICQPGWTGRDCAIEGTQCTPGVCGAGRCENTENDMECLCPLNRSGDRCQYNEILNEHSLNFKGNSFAAYGTPKVTKVNITLSVRPASLEDSVILYTAESTLPSGDYLALVLRGGHAELLINTAARLDPVVVRSAEPLPLNRWTRIEIRRRLGEGILRVGDGPERKAKAPGSDRILSLKTHLYVGGYDRSTVKVNRDVNITKGFDGCISRLYNFQKPVNLLADIKDAANIQSCGETNMIGGDEDSDNEPPVPPPTPDVHENELQPYAMAPCASDPCENGGSCSEQEDVAVCSCPFGFSGKHCQEHLQLGFNASFRGDGYVELNRSHFQPALEQSYTSMGIVFTTNKPNGLLFWWGQEAGEEYTGQDFIAAAVVDGYVEYSMRLDGEEAVIRNSDIRVDNGERHIVIAKRDENTAILEVDRMLHSGETRPTSKKSMKLPGNVFVGGAPDLEVFTGFRYKHNLNGCIVVVEGETVGQINLSSAAVNGVNANVCPANDDPLGGTEPPVV", "length": 3967, "header": "tr|M9NGL3-1|A0ACD4DAU3_DROME Computationally mapped isoform of Terribly reduced optic lobes, isoform BD OS=Drosophila melanogaster OX=7227 GN=trol PE=1 SV=2 CANONICAL=A0ACD4DAU3-1" }, "locus": {} }, { "isoform_ac": "Q7KVZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3/entry#Q7KVZ0-1", "sequence": { "sequence": "MSFVLSCHFDVDCWQCLHSRKSRAKNKCQANEFRCNNGDCIDARKRCNNVSDCSEGEDENEECPAACSGMEYQCRDGTRCISVSQQCDGHSDCSDGDDEEHCDGIVPKLRYTCPKGKFTCRDLSCISIVHRCDGRADCPNDRSDEEGCPCLYDKWQCDDGTCIAKELLCNGNIDCPEDISDERYCEGGYDSEECRFDEFHCGTGECIPMRQVCDNIYDCNDYSDEVNCVEGEEEDRVGIPIGHQPWRPASKHDDWLHEMDTSEYQVYQPSNVYEKANSQNPCASNQFRCTTSNVCIPLHLRCDGFYHCNDMSDEKSCEQYQRHTTTRRPLTLATPTSRITTQGPGLLERRNTTTATEASRWPWATKTTTIATTTSNPITTVGVANSPPQTCLENIEFACHNRDCISIESVCDGIPDCGRNEDEDDALCKCSGDKYKCQRGGGCIPKSQVCDGKPQCHDRSDESACHLHGRLNKTRLGVKCLESQYQCGDGSCISGYKRCNGIHDCADASDEYNCIYDYEDTYDTDPNNNPLNECDILEFECDYSQCLPLEKKCDGYADCEDMSDELECQSYTDHCLESEFECDSYCLPRDQLCNGIPNCQDGSDERNCTFCREDAYLCNTGECVADNQRCNGIADCADGSDERHCARIYCPPNKLACNGTCVSRRIKCDGIRDCLDGYDEMYCPETNNHYPTQNVNVIRPKLGPNPIPKSCRPHEWQCANLECIDSSLQCNEIKDCSDGSDEELSVCFGTATTRLKPSDCSPEQFYCDESCYNRSVRCNGHVDCSDGSDEVGCSLPCPQHQCPSGRCYTESERCDRHRHCEDGSDEANCTAILCKDNEFLCFDRQFCINATQQCDGYYDCRDFSDEQNCIGCYANQFRCNNGDCVSGSAPCNGYSECSDHSDELNCGGTQECLPNQFRCNSGQCVSSSVRCNGRTDCQDSSDEQNCGHRHTEVSQGLETTGVFTTSTTSTTAMTPLRIICPPTSFKCENGPCISLGLKCNGRVDCPYDGSDEADCGQISNDIDPADSNDRRPNQLNLKTYPDSQIIKESREVIFRCRDEGPARAKVKWSRPGGRPLPPGFTDRNGRLEIPNIRVEDAGTYVCEAVGYASYIPGQQVTVNLNVERSWGENKYEEIRSNRIRYGTVPHIDLEFFGLDNDVGSRPESACTEYQATCMNGECIDKSSICDGNPDCSDASDEQSCSLGLKCQPNQFMCSNSKCVDRTWRCDGENDCGDNSDETSCDPEPSGAPCRYNEFQCRSGHCIPKSFQCDNVPDCTDGTDEVGCMAPLPIRPPPQSVSLLEYEVLELTCVATGTPTPTIVWRLNWGHVPDKCESKSYGGTGTLRCPDMRPQDSGAYSCEIINTRGTHFVNPDTIVTVRPVRTDVCEAGFFNMLARKAEECVQCFCFGVAKACDSANLFTYAIHPPILSHRVVSVELSPLRQIVINEAAPGQDLLTLLHGVQFRATNVHFSGRETPYLALPADYMGNQLKSYGGNLRYEVNYRGSGRPVNGPDVIITGNRFTLTYRVRTQPGQNNRVSIPFVPGGWQKPDGRKASREEIMMILANVDNILIRLGYLDSTAREVDLINIALDSAGTADKGLGSASLVEKCQCPPGYVGDSCESCASGYVRQPGGPWLGHCVPFIPDSCPSGTYGDPRRGVPCKECPCPLTGSNNFASGCQQSPDGDVVCRCNEGYTGRRCEQCAAGYQGNPLAAGGICRRIPDTSCNVDGTYSVHSNGTCQCKDSVIGEQCDTCKSKSFHLNSFTYTGCIECFCSGVGLDCDSSTWYRDQVTSTFGRSRVDHGFVLVTNYMQPTPDTVPVSMAAEPNALSFIGSADQSGNTLYWSLPAAFLGNKLSSYGGKLTYTLSYSPLPNGIMSRNSAPDVVIKSGEDLRLIHYRKSQVVPSVANTYSVEIKESAWQRGDEVVANREHVLMALSDITAIYIKATYTTSTKEASLRQVTLDVATPTNLGTPRAVEVEQCRCPEGYLGLSCEQCAPGYARDPEGGIYLGLCRPCECNGHSKYCNSDTGDCEECSDNTEGPSCERCAAGYVGDATRGTIYDCQPDEGYPIPSPPAPGNQTLECTAYCQIEGIYDCRGNECLCKRNVIGDQCDQCRPGTYGLSAQNQDGCKECYCSGLASQCRSAALYRQLIPVDFILNAPLITDESGAVQDTENLIPDISRNMYTYTHTSYLPKYWSLRGSVLGNQLFSYGGRLSYSLIVESYGNYERGHDIVLIGNGLKLIWSRPDGNENQEEYNVRLHEDEQWTRQDRESARPASRSDFMTVLSDLQHILIRATPRVPTQSTSIGNVILESAVTTRTPGATHASDIELCQCPSGYVGTSCESCAPLHYRDASGSCSLCPCDVSNTESCDLVSGGYVECRCKARWKGDRCREIDTNDPTDIGTEDPVLTQIIVSIQKPEITIVPVGGSMTLSCSGRMRWSNSPVIVNWYKENSRLPENVEVQGGNLYLYDLQVSDSGVYICQAVNNETASVFKDTVSITITKKDQLSPAEIVNLPSHVTFEEYVNNEIICEVLGNPAPRVTWARVDGHADAQSTRTYDNRLIFDSPRKSDEGRYRCQAENDQNRDEKYVIVYVQSNPPQPPPQQDRLYITPEEINGLAGESFQLNCQFTSVASLRYDWSHNGRSLSSSPARNVEIRGNTLEVRDASESDSGVYTCVAYDVRTRRNFTESARVNIDRREEQPFGNKPIIESLEQNILIIQGEDYSITCEASGSPYPSIKWAKVHDFMPENVHISGNVLTIYGARFENRGVYSCVAENDHGSDLSSTSIDIEPRERPSVKIVSAPLQTFSVGAPASLYCTVEGIPDPTVEWVRVDGQPLSPRHKIQSPGYMVIDDIQLEDSGDYECRAKNIVGEATGVATITVQEPTLVQIIPDNRDLRLTEGDELSLTCVGSGVPNPEVEWVNEMALKRDLYSPPSNTAILKIYRVTKADAGIYTCHGKNEAGSDEAHVRVEVQERRGDIGGVDDDSDRDPINYNPPQQQNPGIHQPGSNQLLATDIGDNVTLTCDMFQPLNTRWERVDGAPLPRNAYTIKNRLEIVRVEQQNLGQYRCNGIGRDGNVKTYFVKELVLMPLPRIRFYPNIPLTVEAGQNLDVHCQVENVRPEDVHWSTDNNRPLPSSVRIVGSVLRFVSITQAAAGEYRCSAFNQYGNRSQIARVAVKKPADFHQVPQSQLQRHREGENIQLQCTVTDQYGVRAQDNVEFNWFRDDRRPLPNNARTDSQILVLTNLRPEDAGRYICNSYDVDRGQQLPEVSIDLQVLTATPPPNSPIYLPPQLPAKSRDYSLKLDDQSSNLRAGESTDVECYSSDDTYTDVVWERSDGAPLSNNVRQVGNRLVISNVSPSDAGNYVCKCKTDEGDLYTTSYKLEVEDQPHELKSSKIVYAKVGANADLQCGADESRQPTYRWSRQYGQLQAGRSLMNEKLSLDSVQANDAGTYICTAQYADGETADFPNILVVTGAIPQFRQEPRSYMSFPTLPNSSFKFNFELTFRPENGDGLLLFNGQTRGSGDYIALSLKDRYAEFRFDFGGKPMLVRAEEPLALNEWHTVRVSRFKRDGYIQVDEQHPVAFPTLQQIPQLDLIEDLYIGGVPNWELLPADAVSQQVGFVGCISRLTLQGRTVELIREAKYKEGITDCRPCAQGPCQNKGVCLESQTEQAYTCICQPGWTGRDCAIEGTQCTPGVCGAGRCENTENDMECLCPLNRSGDRCQYNEILNEHSLNFKGNSFAAYGTPKVTKVNITLSVRPASLEDSVILYTAESTLPSGDYLALVLRGGHAELLINTAARLDPVVVRSAEPLPLNRWTRIEIRRRLGEGILRVGDGPERKAKAPGSDRILSLKTHLYVGGYDRSTVKVNRDVNITKGFDGCISRLYNFQKPVNLLADIKDAANIQSCGETNMIGGDEDSDNEPPVPPPTPDVHENELQPYAMAPCASDPCENGGSCSEQEDVAVCSCPFGFSGKHCQEHLQLGFNASFRGDGYVELNRSHFQPALEQSYTSMGIVFTTNKPNGLLFWWGQEAGEEYTGQDFIAAAVVDGYVEYSMRLDGEEAVIRNSDIRVDNGERHIVIAKRDENTAILEVDRMLHSGETRPTSKKSMKLPGNVFVGGAPDLEVFTGFRYKHNLNGCIVVVEGETVGQINLSSAAVNGVNANVCPANDDPLGGTEPPVV", "length": 4178, "header": "tr|Q7KVZ0-1|A0ACD4DAU3_DROME Computationally mapped isoform of Terribly reduced optic lobes, isoform BD OS=Drosophila melanogaster OX=7227 GN=trol PE=1 SV=1 CANONICAL=A0ACD4DAU3-1" }, "locus": {} }, { "isoform_ac": "Q8IRV7-1", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3/entry#Q8IRV7-1", "sequence": { "sequence": "MMGSPGSQASAIATSVGIRSGRRGQAGGSLLLRLLAVTFVLAACHAPLLTNAKQISNLGDDQDFMLADDESLQGINDSEWQLMGDDIDDGLLDDVDETLKPMETKSEEEDLPTGNWFSQSVHRVRRSINRLFGSDDNQERGRRQQRERSQRNRDAINRQKELRRRQKEDHNRWKQMRMERQLEKQRLVKRTNHVVFNRATDPRKRASDLYDENEASGYHEEDTTLYRTYFVVNEPYDNEYRDRESVQFQNLQKLLDDDLRNFFHSNYEGNDDEEQEIRSTLERVEPTNDNFKIRVQLRIELPTSVNDFGSKLQQQLNVYNRIENLSAATDGVFSFTESSVTEESVRHLDVGFVEPHITLFHEQNTGYDDFDRKPTTETQDIEEEAIDVTLPQEEVEGSGSDDSSCRGDATFTCPRSGKTICDEMRCDREIQCPDGEDEEYCNYPNVCTEDQFKCDDKCLELKKRCDGSIDCLDQTDEAGCINAPEPEPEPEPEPEPEPESEPEAEPEPEPEPEPESEPEQEPEPQVPEANECQANEFRCNNGDCIDARKRCNNVSDCSEGEDENEECPAACSGMEYQCRDGTRCISVSQQCDGHSDCSDGDDEEHCDGSGYDSEECRFDEFHCGTGECIPMRQVCDNIYDCNDYSDEVNCVEGEEEDRVGIPIGHQPWRPASKHDDWLHEMDTSEYQVYQPSNVYEKANSQNPCASNQFRCTTSNVCIPLHLRCDGFYHCNDMSDEKSCEQYQRHTTTRRPLTLATPTSRITTQGPGLLERRNTTTATEASRWPWATKTTTIATTTSNPITTVGVASCYANQFRCNNGDCVSGSAPCNGYSECSDHSDELNCGGTQECLPNQFRCNSGQCVSSSVRCNGRTDCQDSSDEQNCAADSNDRRPNQLNLKTYPDSQIIKESREVIFRCRDEGPARAKVKWSRPGGRPLPPGFTDRNGRLEIPNIRVEDAGTYVCEAVGYASYIPGQQVTVNLNVERYNDVGSRPESACTEYQATCMNGECIDKSSICDGNPDCSDASDEQSCSLGLKCQPNQFMCSNSKCVDRTWRCDGENDCGDNSDETSCDPEPSGAPCRYNEFQCRSGHCIPKSFQCDNVPDCTDGTDEVGCMAPLPIRPPPQSVSLLEYEVLELTCVATGTPTPTIVWRLNWGHVPDKCESKSYGGTGTLRCPDMRPQDSGAYSCEIINTRGTHFVNPDTIVTVRPVRTDVCEAGFFNMLARKAEECVQCFCFGVAKACDSANLFTYAIHPPILSHRVVSVELSPLRQIVINEAAPGQDLLTLLHGVQFRATNVHFSGRETPYLALPADYMGNQLKSYGGNLRYEVNYRGSGRPVNGPDVIITGNRFTLTYRVRTQPGQNNRVSIPFVPGGWQKPDGRKASREEIMMILANVDNILIRLGYLDSTAREVDLINIALDSAGTADKGLGSASLVEKCQCPPGYVGDSCESCASGYVRQPGGPWLGHCVPFIPDSCPSGTYGDPRRGVPCKECPCPLTGSNNFASGCQQSPDGDVVCRCNEGYTGRRCEQCAAGYQGNPLAAGGICRRIPDTSCNVDGTYSVHSNGTCQCKDSVIGEQCDTCKSKSFHLNSFTYTGCIECFCSGVGLDCDSSTWYRDQVTSTFGRSRVDHGFVLVTNYMQPTPDTVPVSMAAEPNALSFIGSADQSGNTLYWSLPAAFLGNKLSSYGGKLTYTLSYSPLPNGIMSRNSAPDVVIKSGEDLRLIHYRKSQVVPSVANTYSVEIKESAWQRGDEVVANREHVLMALSDITAIYIKATYTTSTKEASLRQVTLDVATPTNLGTPRAVEVEQCRCPEGYLGLSCEQCAPGYARDPEGGIYLGLCRPCECNGHSKYCNSDTGDCEECSDNTEGPSCERCAAGYVGDATRGTIYDCQPDEGYPIPSPPAPGNQTLECTAYCQIEGIYDCRGNECLCKRNVIGDQCDQCRPGTYGLSAQNQDGCKECYCSGLASQCRSAALYRQLIPVDFILNAPLITDESGAVQDTENLIPDISRNMYTYTHTSYLPKYWSLRGSVLGNQLFSYGGRLSYSLIVESYGNYERGHDIVLIGNGLKLIWSRPDGNENQEEYNVRLHEDEQWTRQDRESARPASRSDFMTVLSDLQHILIRATPRVPTQSTSIGNVILESAVTTRTPGATHASDIELCQCPSGYVGTSCESCAPLHYRDASGSCSLCPCDVSNTESCDLVSGGYVECRCKARWKGDRCREIDTNDPTDIGTEDPVLTQIIVSIQKPEITIVPVGGSMTLSCSGRMRWSNSPVIVNWYKENSRLPENVEVQGGNLYLYDLQVSDSGVYICQAVNNETASVFKDTVSITITKKDQLSPAEIVNLPSHVTFEEYVNNEIICEVLGNPAPRVTWARVDGHADAQSTRTYDNRLIFDSPRKSDEGRYRCQAENDQNRDEKYVIVYVQSNPPQPPPQQDRLYITPEEINGLAGESFQLNCQFTSVASLRYDWSHNGRSLSSSPARNVEIRGNTLEVRDASESDSGVYTCVAYDVRTRRNFTESARVNIDRREEQPFGNKPIIESLEQNILIIQGEDYSITCEASGSPYPSIKWAKVHDFMPENVHISGNVLTIYGARFENRGVYSCVAENDHGSDLSSTSIDIEPRERPSVKIVSAPLQTFSVGAPASLYCTVEGIPDPTVEWVRVDGQPLSPRHKIQSPGYMVIDDIQLEDSGDYECRAKNIVGEATGVATITVQEPTLVQIIPDNRDLRLTEGDELSLTCVGSGVPNPEVEWVNEMALKRDLYSPPSNTAILKIYRVTKADAGIYTCHGKNEAGSDEAHVRVEVQERRGDIGGVDDDSDRDPINYNPPQQQNPGIHQPGSNQLLATDIGDNVTLTCDMFQPLNTRWERVDGAPLPRNAYTIKNRLEIVRVEQQNLGQYRCNGIGRDGNVKTYFVKELVLMPLPRIRFYPNIPLTVEAGQNLDVHCQVENVRPEDVHWSTDNNRPLPSSVRIVGSVLRFVSITQAAAGEYRCSAFNQYGNRSQIARVAVKKPADFHQVPQSQLQRHREGENIQLQCTVTDQYGVRAQDNVEFNWFRDDRRPLPNNARTDSQILVLTNLRPEDAGRYICNSYDVDRGQQLPEVSIDLQVLSE", "length": 3105, "header": "tr|Q8IRV7-1|A0ACD4DAU3_DROME Computationally mapped isoform of Terribly reduced optic lobes, isoform BD OS=Drosophila melanogaster OX=7227 GN=trol PE=1 SV=3 CANONICAL=A0ACD4DAU3-1" }, "locus": {} }, { "isoform_ac": "Q8IRV8-1", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3/entry#Q8IRV8-1", "sequence": { "sequence": "MMGSPGSQASAIATSVGIRSGRRGQAGGSLLLRLLAVTFVLAACHAPLLTNAKQISNLGDDQDFMLADDESLQGINDSEWQLMGDDIDDGLLDDVDETLKPMETKSEEEDLPTGNWFSQSVHRVRRSINRLFGSDDNQERGRRQQRERSQRNRDAINRQKELRRRQKEDHNRWKQMRMERQLEKQRLVKRTNHVVFNRATDPRKRASDLYDENEASGYHEEDTTLYRTYFVVNEPYDNEYRDRESVQFQNLQKLLDDDLRNFFHSNYEGNDDEEQEIRSTLERVEPTNDNFKIRVQLRIELPTSVNDFGSKLQQQLNVYNRIENLSAATDGVFSFTESSDIEEEAIDVTLPQEEVEGSGSDDSSCRGDATFTCPRSGKTICDEMRCDREIQCPDGEDEEYCNYPNVCTEDQFKCDDKCLELKKRCDGSIDCLDQTDEAGCINAPEPEPEPEPEPEPEPESEPEAEPEPEPEPEPESEPEQEPEPQVPEANECQANEFRCNNGDCIDARKRCNNVSDCSEGEDENEECHSPPQTCLENIEFACHNRDCISIESVCDGIPDCGRNEDEDDALCKCSGDKYKCQRGGGCIPKSQVCDGKPQCHDRSDESACPTTRLKPSDCSPEQFYCDESCYNRSVRCNGHVDCSDGSDEVGCSLPCPQHQCPSGRCYTESERCDRHRHCEDGSDEANCCYANQFRCNNGDCVSGSAPCNGYSECSDHSDELNCGGTQECLPNQFRCNSGQCVSSSVRCNGRTDCQDSSDEQNCAADSNDRRPNQLNLKTYPDSQIIKESREVIFRCRDEGPARAKVKWSRPGGRPLPPGFTDRNGRLEIPNIRVEDAGTYVCEAVGYASYIPGQQVTVNLNVERYNDVGSRPESACTEYQATCMNGECIDKSSICDGNPDCSDASDEQSCSLGLKCQPNQFMCSNSKCVDRTWRCDGENDCGDNSDETSCDPEPSGAPCRYNEFQCRSGHCIPKSFQCDNVPDCTDGTDEVGCMAPLPIRPPPQSVSLLEYEVLELTCVATGTPTPTIVWRLNWGHVPDKCESKSYGGTGTLRCPDMRPQDSGAYSCEIINTRGTHFVNPDTIVTVRPVRTDVCEAGFFNMLARKAEECVQCFCFGVAKACDSANLFTYAIHPPILSHRVVSVELSPLRQIVINEAAPGQDLLTLLHGVQFRATNVHFSGRETPYLALPADYMGNQLKSYGGNLRYEVNYRGSGRPVNGPDVIITGNRFTLTYRVRTQPGQNNRVSIPFVPGGWQKPDGRKASREEIMMILANVDNILIRLGYLDSTAREVDLINIALDSAGTADKGLGSASLVEKCQCPPGYVGDSCESCASGYVRQPGGPWLGHCVPFIPDSCPSGTYGDPRRGVPCKECPCPLTGSNNFASGCQQSPDGDVVCRCNEGYTGRRCEQCAAGYQGNPLAAGGICRRIPDTSCNVDGTYSVHSNGTCQCKDSVIGEQCDTCKSKSFHLNSFTYTGCIECFCSGVGLDCDSSTWYRDQVTSTFGRSRVDHGFVLVTNYMQPTPDTVPVSMAAEPNALSFIGSADQSGNTLYWSLPAAFLGNKLSSYGGKLTYTLSYSPLPNGIMSRNSAPDVVIKSGEDLRLIHYRKSQVVPSVANTYSVEIKESAWQRGDEVVANREHVLMALSDITAIYIKATYTTSTKEASLRQVTLDVATPTNLGTPRAVEVEQCRCPEGYLGLSCEQCAPGYARDPEGGIYLGLCRPCECNGHSKYCNSDTGDCEECSDNTEGPSCERCAAGYVGDATRGTIYDCQPDEGYPIPSPPAPGNQTLECTAYCQIEGIYDCRGNECLCKRNVIGDQCDQCRPGTYGLSAQNQDGCKECYCSGLASQCRSAALYRQLIPVDFILNAPLITDESGAVQDTENLIPDISRNMYTYTHTSYLPKYWSLRGSVLGNQLFSYGGRLSYSLIVESYGNYERGHDIVLIGNGLKLIWSRPDGNENQEEYNVRLHEDEQWTRQDRESARPASRSDFMTVLSDLQHILIRATPRVPTQSTSIGNVILESAVTTRTPGATHASDIELCQCPSGYVGTSCESCAPLHYRDASGSCSLCPCDVSNTESCDLVSGGYVECRCKARWKGDRCREIDTNDPTDIGTEDPVLTQIIVSIQKPEITIVPVGGSMTLSCSGRMRWSNSPVIVNWYKENSRLPENVEVQGGNLYLYDLQVSDSGVYICQAVNNETASVFKDTVSITITKKDQLSPAEIVNLPSHVTFEEYVNNEIICEVLGNPAPRVTWARVDGHADAQSTRTYDNRLIFDSPRKSDEGRYRCQAENDQNRDEKYVIVYVQSNPPQPPPQQDRLYITPEEINGLAGESFQLNCQFTSVASLRYDWSHNGRSLSSSPARNVEIRGNTLEVRDASESDSGVYTCVAYDVRTRRNFTESARVNIDRREEQPFGNKPIIESLEQNILIIQGEDYSITCEASGSPYPSIKWAKVHDFMPENVHISGNVLTIYGARFENRGVYSCVAENDHGSDLSSTSIDIEPRERPSVKIVSAPLQTFSVGAPASLYCTVEGIPDPTVEWVRVDGQPLSPRHKIQSPGYMVIDDIQLEDSGDYECRAKNIVGEATGVATITVQEPTLVQIIPDNRDLRLTEGDELSLTCVGSGVPNPEVEWVNEMALKRDLYSPPSNTAILKIYRVTKADAGIYTCHGKNEAGSDEAHVRVEVQERRGDIGGVDDDSDRDPINYNPPQQQNPGIHQPGSNQLLATDIGDNVTLTCDMFQPLNTRWERVDGAPLPRNAYTIKNRLEIVRVEQQNLGQYRCNGIGRDGNVKTYFVKELVLMPLPRIRFYPNIPLTVEAGQNLDVHCQVENVRPEDVHWSTDNNRPLPSSVRIVGSVLRFVSITQAAAGEYRCSAFNQYGNRSQIARVAVKKPADFHQVPQSQLQRHREGENIQLQCTVTDQYGVRAQDNVEFNWFRDDRRPLPNNARTDSQILVLTNLRPEDAGRYICNSYDVDRGQQLPEVSIDLQVLTATPPPNSPIYLPPQLPAKSRDYSLKLDDQSSNLRAGESTDVECYSSDDTYTDVVWERSDGAPLSNNVRQVGNRLVISNVSPSDAGNYVCKCKTDEGDLYTTSYKLEVEDQPHELKSSKIVYAKVGANADLQCGADESRQPTYRWSRQYGQLQAGRSLMNEKLSLDSVQANDAGTYICTAQYADGETADFPNILVVTGAIPQFRQEPRSYMSFPTLPNSSFKFNFELTFRPENGDGLLLFNGQTRGSGDYIALSLKDRYAEFRFDFGGKPMLVRAEEPLALNEWHTVRVSRFKRDGYIQVDEQHPVAFPTLQQIPQLDLIEDLYIGGVPNWELLPADAVSQQVGFVGCISRLTLQGRTVELIREAKYKEGITDCRPCAQGPCQNKGVCLESQTEQAYTCICQPGWTGRDCAIEGTQCTPGVCGAGRCENTENDMECLCPLNRSGDRCQYNEILNEHSLNFKGNSFAAYGTPKVTKVNITLSVRPASLEDSVILYTAESTLPSGDYLALVLRGGHAELLINTAARLDPVVVRSAEPLPLNRWTRIEIRRRLGEGILRVGDGPERKAKAPGSDRILSLKTHLYVGGYDRSTVKVNRDVNITKGFDGCISRLYNFQKPVNLLADIKDAANIQSCGETNMIGGDEDSDNEPPVPPPTPDVHENELQPYAMAPCASDPCENGGSCSEQEDVAVCSCPFGFSGKHCQEHLQLGFNASFRGDGYVELNRSHFQPALEQSYTSMGIVFTTNKPNGLLFWWGQEAGEEYTGQDFIAAAVVDGYVEYSMRLDGEEAVIRNSDIRVDNGERHIVIAKRDENTAILEVDRMLHSGETRPTSKKSMKLPGNVFVGGAPDLEVFTGFRYKHNLNGCIVVVEGETVGQINLSSAAVNGVNANVCPANDDPLGGTEPPVV", "length": 3887, "header": "tr|Q8IRV8-1|A0ACD4DAU3_DROME Computationally mapped isoform of Terribly reduced optic lobes, isoform BD OS=Drosophila melanogaster OX=7227 GN=trol PE=1 SV=3 CANONICAL=A0ACD4DAU3-1" }, "locus": {} }, { "isoform_ac": "Q8IRV9-1", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3/entry#Q8IRV9-1", "sequence": { "sequence": "MMGSPGSQASAIATSVGIRSGRRGQAGGSLLLRLLAVTFVLAACHAPLLTNAKQISNLGDDQDFMLADDESLQGINDSEWQLMGDDIDDGLLDDVDETLKPMETKSEEEDLPTGNWFSQSVHRVRRSINRLFGSDDNQERGRRQQRERSQRNRDAINRQKELRRRQKEDHNRWKQMRMERQLEKQRLVKRTNHVVFNRATDPRKRASDLYDENEASGYHEEDTTLYRTYFVVNEPYDNEYRDRESVQFQNLQKLLDDDLRNFFHSNYEGNDDEEQEIRSTLERVEPTNDNFKIRVQLRIELPTSVNDFGSKLQQQLNVYNRIENLSAATDGVFSFTESSVTEESVRHLDVGFVEPHITLFHEQNTGYDDFDRKPTTETQDIEEEAIDVTLPQEEVEGSGSDDSSCRGDATFTCPRSGKTICDEMRCDREIQCPDGEDEEYCNYPNVCTEDQFKCDDKCLELKKRCDGSIDCLDQTDEAGCINAPEPEPEPEPEPEPEPESEPEAEPEPEPEPEPESEPEQEPEPQVPEANECQANEFRCNNGDCIDARKRCNNVSDCSEGEDENEECPAACSGMEYQCRDGTRCISVSQQCDGHSDCSDGDDEEHCDGSGYDSEECRFDEFHCGTGECIPMRQVCDNIYDCNDYSDEVNCVEGEEEDRVGIPIGHQPWRPASKHDDWLHEMDTSEYQVYQPSNVYEKANSQNPCASNQFRCTTSNVCIPLHLRCDGFYHCNDMSDEKSCEQYQRHTTTRRPLTLATPTSRITTQGPGLLERRNTTTATEASRWPWATKTTTIATTTSNPITTVGVASCYANQFRCNNGDCVSGSAPCNGYSECSDHSDELNCGGTQECLPNQFRCNSGQCVSSSVRCNGRTDCQDSSDEQNCAADSNDRRPNQLNLKTYPDSQIIKESREVIFRCRDEGPARAKVKWSRPGGRPLPPGFTDRNGRLEIPNIRVEDAGTYVCEAVGYASYIPGQQVTVNLNVERYNDVGSRPESACTEYQATCMNGECIDKSSICDGNPDCSDASDEQSCSLGLKCQPNQFMCSNSKCVDRTWRCDGENDCGDNSDETSCDPEPSGAPCRYNEFQCRSGHCIPKSFQCDNVPDCTDGTDEVGCMAPLPIRPPPQSVSLLEYEVLELTCVATGTPTPTIVWRLNWGHVPDKCESKSYGGTGTLRCPDMRPQDSGAYSCEIINTRGTHFVNPDTIVTVRPVRTDVCEAGFFNMLARKAEECVQCFCFGVAKACDSANLFTYAIHPPILSHRVVSVELSPLRQIVINEAAPGQDLLTLLHGVQFRATNVHFSGRETPYLALPADYMGNQLKSYGGNLRYEVNYRGSGRPVNGPDVIITGNRFTLTYRVRTQPGQNNRVSIPFVPGGWQKPDGRKASREEIMMILANVDNILIRLGYLDSTAREVDLINIALDSAGTADKGLGSASLVEKCQCPPGYVGDSCESCASGYVRQPGGPWLGHCVPFIPDSCPSGTYGDPRRGVPCKECPCPLTGSNNFASGCQQSPDGDVVCRCNEGYTGRRCEQCAAGYQGNPLAAGGICRRIPDTSCNVDGTYSVHSNGTCQCKDSVIGEQCDTCKSKSFHLNSFTYTGCIECFCSGVGLDCDSSTWYRDQVTSTFGRSRVDHGFVLVTNYMQPTPDTVPVSMAAEPNALSFIGSADQSGNTLYWSLPAAFLGNKLSSYGGKLTYTLSYSPLPNGIMSRNSAPDVVIKSGEDLRLIHYRKSQVVPSVANTYSVEIKESAWQRGDEVVANREHVLMALSDITAIYIKATYTTSTKEASLRQVTLDVATPTNLGTPRAVEVEQCRCPEGYLGLSCEQCAPGYARDPEGGIYLGLCRPCECNGHSKYCNSDTGDCEECSDNTEGPSCERCAAGYVGDATRGTIYDCQPDEGYPIPSPPAPGNQTLECTAYCQIEGIYDCRGNECLCKRNVIGDQCDQCRPGTYGLSAQNQDGCKECYCSGLASQCRSAALYRQLIPVDFILNAPLITDESGAVQDTENLIPDISRNMYTYTHTSYLPKYWSLRGSVLGNQLFSYGGRLSYSLIVESYGNYERGHDIVLIGNGLKLIWSRPDGNENQEEYNVRLHEDEQWTRQDRESARPASRSDFMTVLSDLQHILIRATPRVPTQSTSIGNVILESAVTTRTPGATHASDIELCQCPSGYVGTSCESCAPLHYRDASGSCSLCPCDVSNTESCDLVSGGYVECRCKARWKGDRCREIDTNDPTDIGTEDPVLTQIIVSIQKPEITIVPVGGSMTLSCSGRMRWSNSPVIVNWYKENSRLPENVEVQGGNLYLYDLQVSDSGVYICQAVNNETASVFKDTVSITITKKDQLSPAEIVNLPSHVTFEEYVNNEIICEVLGNPAPRVTWARVDGHADAQSTRTYDNRLIFDSPRKSDEGRYRCQAENDQNRDEKYVIVYVQSNPPQPPPQQDRLYITPEEINGLAGESFQLNCQFTSVASLRYDWSHNGRSLSSSPARNVEIRGNTLEVRDASESDSGVYTCVAYDVRTRRNFTESARVNIDRREEQPFGNKPIIESLEQNILIIQGEDYSITCEASGSPYPSIKWAKVHDFMPENVHISGNVLTIYGARFENRGVYSCVAENDHGSDLSSTSIDIEPRERPSVKIVSAPLQTFSVGAPASLYCTVEGIPDPTVEWVRVDGQPLSPRHKIQSPGYMVIDDIQLEDSGDYECRAKNIVGEATGVATITVQEPTLVQIIPDNRDLRLTEGDELSLTCVGSGVPNPEVEWVNEMALKRDLYSPPSNTAILKIYRVTKADAGIYTCHGKNEAGSDEAHVRVEVQERRGDIGGVDDDSDRDPINYNPPQQQNPGIHQPGSNQLLATDIGDNVTLTCDMFQPLNTRWERVDGAPLPRNAYTIKNRLEIVRVEQQNLGQYRCNGIGRDGNVKTYFVKELVLMPLPRIRFYPNIPLTVEAGQNLDVHCQVENVRPEDVHWSTDNNRPLPSSVRIVGSVLRFVSITQAAAGEYRCSAFNQYGNRSQIARVAVKKPADFHQVPQSQLQRHREGENIQLQCTVTDQYGVRAQDNVEFNWFRDDRRPLPNNARTDSQILVLTNLRPEDAGRYICNSYDVDRGQQLPEVSIDLQVLTATPPPNSPIYLPPQLPAKSRDYSLKLDDQSSNLRAGESTDVECYSSDDTYTDVVWERSDGAPLSNNVRQVGNRLVISNVSPSDAGNYVCKCKTDEGDLYTTSYKLEVEDQPHELKSSKIVYAKVGANADLQCGADESRQPTYRWSRQYGQLQAGRSLMNEKLSLDSVQANDAGTYICTAQYADGETADFPNILVVTGAIPQFRQEPRSYMSFPTLPNSSFKFNFELTFRPENGDGLLLFNGQTRGSGDYIALSLKDRYAEFRFDFGGKPMLVRAEEPLALNEWHTVRVSRFKRDGYIQVDEQHPVAFPTLQQIPQLDLIEDLYIGGVPNWELLPADAVSQQVGFVGCISRLTLQGRTVELIREAKYKEGITDCRPCAQGPCQNKGVCLESQTEQAYTCICQPGWTGRDCAIEGTQCTPGVCGAGRCENTENDMECLCPLNRSGDRCQYNEILNEHSLNFKGNSFAAYGTPKVTKVNITLSVRPASLEDSVILYTAESTLPSGDYLALVLRGGHAELLINTAARLDPVVVRSAEPLPLNRWTRIEIRRRLGEGILRVGDGPERKAKAPGSDRILSLKTHLYVGGYDRSTVKVNRDVNITKGFDGCISRLYNFQKPVNLLADIKDAANIQSCGETNMIGGDEDSDNEPPVPPPTPDVHENELQPYAMAPCASDPCENGGSCSEQEDVAVCSCPFGFSGKHCQEHLQLGFNASFRGDGYVELNRSHFQPALEQSYTSMGIVFTTNKPNGLLFWWGQEAGEEYTGQDFIAAAVVDGYVEYSMRLDGEEAVIRNSDIRVDNGERHIVIAKRDENTAILEVDRMLHSGETRPTSKKSMKLPGNVFVGGAPDLEVFTGFRYKHNLNGCIVVVEGETVGQINLSSAAVNGVNANVCPANDDPLGGTEPPVV", "length": 4007, "header": "tr|Q8IRV9-1|A0ACD4DAU3_DROME Computationally mapped isoform of Terribly reduced optic lobes, isoform BD OS=Drosophila melanogaster OX=7227 GN=trol PE=1 SV=3 CANONICAL=A0ACD4DAU3-1" }, "locus": {} }, { "isoform_ac": "Q9W4Y3-1", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3/entry#Q9W4Y3-1", "sequence": { "sequence": "MMGSPGSQASAIATSVGIRSGRRGQAGGSLLLRLLAVTFVLAACHAPLLTNAKQISNLGDDQDFMLADDESLQGINDSEWQLMGDDIDDGLLDDVDETLKPMETKSEEEDLPTGNWFSQSVHRVRRSINRLFGSDDNQERGRRQQRERSQRNRDAINRQKELRRRQKEDHNRWKQMRMERQLEKQRLVKRTNHVVFNRATDPRKRASDLYDENEASGYHEEDTTLYRTYFVVNEPYDNEYRDRESVQFQNLQKLLDDDLRNFFHSNYEGNDDEEQEIRSTLERVEPTNDNFKIRVQLRIELPTSVNDFGSKLQQQLNVYNRIENLSAATDGVFSFTESSVTEESVRHLDVGFVEPHITLFHEQNTGYDDFDRKPTTETQDIEEEAIDVTLPQEEVEGSGSDDSSCRGDATFTCPRSGKTICDEMRCDREIQCPDGEDEEYCNYPNVCTEDQFKCDDKCLELKKRCDGSIDCLDQTDEAGCINAPEPEPEPEPEPEPEPESEPEAEPEPEPEPEPESEPEQEPEPQVPEANECQANEFRCNNGDCIDARKRCNNVSDCSEGEDENEECPAACSGMEYQCRDGTRCISVSQQCDGHSDCSDGDDEEHCDGSGYDSEECRFDEFHCGTGECIPMRQVCDNIYDCNDYSDEVNCVEGEEEDRVGIPIGHQPWRPASKHDDWLHEMDTSEYQVYQPSNVYEKANSQNPCASNQFRCTTSNVCIPLHLRCDGFYHCNDMSDEKSCEQYQRHTTTRRPLTLATPTSRITTQGPGLLERRNTTTATEASRWPWATKTTTIATTTSNPITTVGVANSPPQTCLENIEFACHNRDCISIESVCDGIPDCGRNEDEDDALCKCSGDKYKCQRGGGCIPKSQVCDGKPQCHDRSDESACHLHGRLNKTRLGVKCLESQYQCGDGSCISGYKRCNGIHDCADASDEYNCIYDYEDTYDTDPNNNPLNECDILEFECDYSQCLPLEKKCDGYADCEDMSDELECQSYTDHCLESEFECDSYCLPRDQLCNGIPNCQDGSDERNCTFCREDAYLCNTGECVADNQRCNGIADCADGSDERHCARIYCPPNKLACNGTCVSRRIKCDGIRDCLDGYDEMYCPETNNHYPTQNVNVIRPKLGPNPIPKSCRPHEWQCANLECIDSSLQCNEIKDCSDGSDEELSVCFGTATTRLKPSDCSPEQFYCDESCYNRSVRCNGHVDCSDGSDEVGCSLPCPQHQCPSGRCYTESERCDRHRHCEDGSDEANCCYANQFRCNNGDCVSGSAPCNGYSECSDHSDELNCGGTQECLPNQFRCNSGQCVSSSVRCNGRTDCQDSSDEQNCAADSNDRRPNQLNLKTYPDSQIIKESREVIFRCRDEGPARAKVKWSRPGGRPLPPGFTDRNGRLEIPNIRVEDAGTYVCEAVGYASYIPGQQVTVNLNVERYNDVGSRPESACTEYQATCMNGECIDKSSICDGNPDCSDASDEQSCSLGLKCQPNQFMCSNSKCVDRTWRCDGENDCGDNSDETSCDPEPSGAPCRYNEFQCRSGHCIPKSFQCDNVPDCTDGTDEVGCMAPLPIRPPPQSVSLLEYEVLELTCVATGTPTPTIVWRLNWGHVPDKCESKSYGGTGTLRCPDMRPQDSGAYSCEIINTRGTHFVNPDTIVTVRPVRTDVCEAGFFNMLARKAEECVQCFCFGVAKACDSANLFTYAIHPPILSHRVVSVELSPLRQIVINEAAPGQDLLTLLHGVQFRATNVHFSGRETPYLALPADYMGNQLKSYGGNLRYEVNYRGSGRPVNGPDVIITGNRFTLTYRVRTQPGQNNRVSIPFVPGGWQKPDGRKASREEIMMILANVDNILIRLGYLDSTAREVDLINIALDSAGTADKGLGSASLVEKCQCPPGYVGDSCESCASGYVRQPGGPWLGHCVPFIPDSCPSGTYGDPRRGVPCKECPCPLTGSNNFASGCQQSPDGDVVCRCNEGYTGRRCEQCAAGYQGNPLAAGGICRRIPDTSCNVDGTYSVHSNGTCQCKDSVIGEQCDTCKSKSFHLNSFTYTGCIECFCSGVGLDCDSSTWYRDQVTSTFGRSRVDHGFVLVTNYMQPTPDTVPVSMAAEPNALSFIGSADQSGNTLYWSLPAAFLGNKLSSYGGKLTYTLSYSPLPNGIMSRNSAPDVVIKSGEDLRLIHYRKSQVVPSVANTYSVEIKESAWQRGDEVVANREHVLMALSDITAIYIKATYTTSTKEASLRQVTLDVATPTNLGTPRAVEVEQCRCPEGYLGLSCEQCAPGYARDPEGGIYLGLCRPCECNGHSKYCNSDTGDCEECSDNTEGPSCERCAAGYVGDATRGTIYDCQPDEGYPIPSPPAPGNQTLECTAYCQIEGIYDCRGNECLCKRNVIGDQCDQCRPGTYGLSAQNQDGCKECYCSGLASQCRSAALYRQLIPVDFILNAPLITDESGAVQDTENLIPDISRNMYTYTHTSYLPKYWSLRGSVLGNQLFSYGGRLSYSLIVESYGNYERGHDIVLIGNGLKLIWSRPDGNENQEEYNVRLHEDEQWTRQDRESARPASRSDFMTVLSDLQHILIRATPRVPTQSTSIGNVILESAVTTRTPGATHASDIELCQCPSGYVGTSCESCAPLHYRDASGSCSLCPCDVSNTESCDLVSGGYVECRCKARWKGDRCREIDTNDPTDIGTEDPVLTQIIVSIQKPEITIVPVGGSMTLSCSGRMRWSNSPVIVNWYKENSRLPENVEVQGGNLYLYDLQVSDSGVYICQAVNNETASVFKDTVSITITKKDQLSPAEIVNLPSHVTFEEYVNNEIICEVLGNPAPRVTWARVDGHADAQSTRTYDNRLIFDSPRKSDEGRYRCQAENDQNRDEKYVIVYVQSNPPQPPPQQDRLYITPEEINGLAGESFQLNCQFTSVASLRYDWSHNGRSLSSSPARNVEIRGNTLEVRDASESDSGVYTCVAYDVRTRRNFTESARVNIDRREEQPFGNKPIIESLEQNILIIQGEDYSITCEASGSPYPSIKWAKVHDFMPENVHISGNVLTIYGARFENRGVYSCVAENDHGSDLSSTSIDIEPRERPSVKIVSAPLQTFSVGAPASLYCTVEGIPDPTVEWVRVDGQPLSPRHKIQSPGYMVIDDIQLEDSGDYECRAKNIVGEATGVATITVQEPTLVQIIPDNRDLRLTEGDELSLTCVGSGVPNPEVEWVNEMALKRDLYSPPSNTAILKIYRVTKADAGIYTCHGKNEAGSDEAHVRVEVQERRGDIGGVDDDSDRDPINYNPPQQQNPGIHQPGSNQLLATDIGDNVTLTCDMFQPLNTRWERVDGAPLPRNAYTIKNRLEIVRVEQQNLGQYRCNGIGRDGNVKTYFVKELVLMPLPRIRFYPNIPLTVEAGQNLDVHCQVENVRPEDVHWSTDNNRPLPSSVRIVGSVLRFVSITQAAAGEYRCSAFNQYGNRSQIARVAVKKPADFHQVPQSQLQRHREGENIQLQCTVTDQYGVRAQDNVEFNWFRDDRRPLPNNARTDSQILVLTNLRPEDAGRYICNSYDVDRGQQLPEVSIDLQVLRAPQYPYNRFKGGVSLKDTPCMVLYICAAATPPPNSPIYLPPQLPAKSRDYSLKLDDQSSNLRAGESTDVECYSSDDTYTDVVWERSDGAPLSNNVRQVGNRLVISNVSPSDAGNYVCKCKTDEGDLYTTSYKLEVEDQPHELKSSKIVYAKVGANADLQCGADESRQPTYRWSRQYGQLQAGRSLMNEKLSLDSVQANDAGTYICTAQYADGETADFPNILVVTGAIPQFRQEPRSYMSFPTLPNSSFKFNFELTFRPENGDGLLLFNGQTRGSGDYIALSLKDRYAEFRFDFGGKPMLVRAEEPLALNEWHTVRVSRFKRDGYIQVDEQHPVAFPTLQQIPQLDLIEDLYIGGVPNWELLPADAVSQQVGFVGCISRLTLQGRTVELIREAKYKEGITDCRPCAQGPCQNKGVCLESQTEQAYTCICQPGWTGRDCAIEGTQCTPGVCGAGRCENTENDMECLCPLNRSGDRCQYNEILNEHSLNFKGNSFAAYGTPKVTKVNITLSVRPASLEDSVILYTAESTLPSGDYLALVLRGGHAELLINTAARLDPVVVRSAEPLPLNRWTRIEIRRRLGEGILRVGDGPERKAKAPGSDRILSLKTHLYVGGYDRSTVKVNRDVNITKGFDGCISRLYNFQKPVNLLADIKDAANIQSCGETNMIGGDEDSDNEPPVPPPTPDVHENELQPYAMAPCASDPCENGGSCSEQEDVAVCSCPFGFSGKHCQEHLQLGFNASFRGDGYVELNRSHFQPALEQSYTSMGIVFTTNKPNGLLFWWGQEAGEEYTGQDFIAAAVVDGYVEYSMRLDGEEAVIRNSDIRVDNGERHIVIAKRDENTAILEVDRMLHSGETRPTSKKSMKLPGNVFVGGAPDLEVFTGFRYKHNLNGCIVVVEGETVGQINLSSAAVNGVNANVCPANDDPLGGTEPPVV", "length": 4479, "header": "tr|Q9W4Y3-1|A0ACD4DAU3_DROME Computationally mapped isoform of Terribly reduced optic lobes, isoform BD OS=Drosophila melanogaster OX=7227 GN=trol PE=1 SV=4 CANONICAL=A0ACD4DAU3-1" }, "locus": {} }, { "isoform_ac": "Q9W4Y4-1", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3/entry#Q9W4Y4-1", "sequence": { "sequence": "MMGSPGSQASAIATSVGIRSGRRGQAGGSLLLRLLAVTFVLAACHAPLLTNAKQISNLGDDQDFMLADDESLQGINDSEWQLMGDDIDDGLLDDVDETLKPMETKSEEEDLPTGNWFSQSVHRVRRSINRLFGSDDNQERGRRQQRERSQRNRDAINRQKELRRRQKEDHNRWKQMRMERQLEKQRLVKRTNHVVFNRATDPRKRASDLYDENEASGYHEEDTTLYRTYFVVNEPYDNEYRDRESVQFQNLQKLLDDDLRNFFHSNYEGNDDEEQEIRSTLERVEPTNDNFKIRVQLRIELPTSVNDFGSKLQQQLNVYNRIENLSAATDGVFSFTESSDIEEEAIDVTLPQEEVEGSGSDDSSCRGDATFTCPRSGKTICDEMRCDREIQCPDGEDEEYCNYPNVCTEDQFKCDDKCLELKKRCDGSIDCLDQTDEAGCINAPEPEPEPEPEPEPEPESEPEAEPEPEPEPEPESEPEQEPEPQVPEANECQANEFRCNNGDCIDARKRCNNVSDCSEGEDENEECLEGEEEDRVGIPIGHQPWRPASKHDDWLHEMDTSEYQVYQPSNVYEKANSQNPCASNQFRCTTSNVCIPLHLRCDGFYHCNDMSDEKSCEQYQRHTTTRRPLTLATPTSRITTQGPGLLERRNTTTATEASRWPWATKTTTIATTTSNPITTVGVANSPPQTCLENIEFACHNRDCISIESVCDGIPDCGRNEDEDDALCKCSGDKYKCQRGGGCIPKSQVCDGKPQCHDRSDESACHLHGRLNKTRLGVKCLESQYQCGDGSCISGYKRCNGIHDCADASDEYNCIYDYEDTYDTDPNNNPLNECDILEFECDYSQCLPLEKKCDGYADCEDMSDELECQSYTATTRLKPSDCSPEQFYCDESCYNRSVRCNGHVDCSDGSDEVGCSLPCPQHQCPSGRCYTESERCDRHRHCEDGSDEANCCYANQFRCNNGDCVSGSAPCNGYSECSDHSDELNCGGTQECLPNQFRCNSGQCVSSSVRCNGRTDCQDSSDEQNCAADSNDRRPNQLNLKTYPDSQIIKESREVIFRCRDEGPARAKVKWSRPGGRPLPPGFTDRNGRLEIPNIRVEDAGTYVCEAVGYASYIPGQQVTVNLNVERYNDVGSRPESACTEYQATCMNGECIDKSSICDGNPDCSDASDEQSCSLGLKCQPNQFMCSNSKCVDRTWRCDGENDCGDNSDETSCDPEPSGAPCRYNEFQCRSGHCIPKSFQCDNVPDCTDGTDEVGCMAPLPIRPPPQSVSLLEYEVLELTCVATGTPTPTIVWRLNWGHVPDKCESKSYGGTGTLRCPDMRPQDSGAYSCEIINTRGTHFVNPDTIVTVRPVRTDVCEAGFFNMLARKAEECVQCFCFGVAKACDSANLFTYAIHPPILSHRVVSVELSPLRQIVINEAAPGQDLLTLLHGVQFRATNVHFSGRETPYLALPADYMGNQLKSYGGNLRYEVNYRGSGRPVNGPDVIITGNRFTLTYRVRTQPGQNNRVSIPFVPGGWQKPDGRKASREEIMMILANVDNILIRLGYLDSTAREVDLINIALDSAGTADKGLGSASLVEKCQCPPGYVGDSCESCASGYVRQPGGPWLGHCVPFIPDSCPSGTYGDPRRGVPCKECPCPLTGSNNFASGCQQSPDGDVVCRCNEGYTGRRCEQCAAGYQGNPLAAGGICRRIPDTSCNVDGTYSVHSNGTCQCKDSVIGEQCDTCKSKSFHLNSFTYTGCIECFCSGVGLDCDSSTWYRDQVTSTFGRSRVDHGFVLVTNYMQPTPDTVPVSMAAEPNALSFIGSADQSGNTLYWSLPAAFLGNKLSSYGGKLTYTLSYSPLPNGIMSRNSAPDVVIKSGEDLRLIHYRKSQVVPSVANTYSVEIKESAWQRGDEVVANREHVLMALSDITAIYIKATYTTSTKEASLRQVTLDVATPTNLGTPRAVEVEQCRCPEGYLGLSCEQCAPGYARDPEGGIYLGLCRPCECNGHSKYCNSDTGDCEECSDNTEGPSCERCAAGYVGDATRGTIYDCQPDEGYPIPSPPAPGNQTLECTAYCQIEGIYDCRGNECLCKRNVIGDQCDQCRPGTYGLSAQNQDGCKECYCSGLASQCRSAALYRQLIPVDFILNAPLITDESGAVQDTENLIPDISRNMYTYTHTSYLPKYWSLRGSVLGNQLFSYGGRLSYSLIVESYGNYERGHDIVLIGNGLKLIWSRPDGNENQEEYNVRLHEDEQWTRQDRESARPASRSDFMTVLSDLQHILIRATPRVPTQSTSIGNVILESAVTTRTPGATHASDIELCQCPSGYVGTSCESCAPLHYRDASGSCSLCPCDVSNTESCDLVSGGYVECRCKARWKGDRCREIDTNDPTDIGTEDPVLTQIIVSIQKPEITIVPVGGSMTLSCSGRMRWSNSPVIVNWYKENSRLPENVEVQGGNLYLYDLQVSDSGVYICQAVNNETASVFKDTVSITITKKDQLSPAEIVNLPSHVTFEEYVNNEIICEVLGNPAPRVTWARVDGHADAQSTRTYDNRLIFDSPRKSDEGRYRCQAENDQNRDEKYVIVYVQSNPPQPPPQQDRLYITPEEINGLAGESFQLNCQFTSVASLRYDWSHNGRSLSSSPARNVEIRGNTLEVRDASESDSGVYTCVAYDVRTRRNFTESARVNIDRREEQPFGNKPIIESLEQNILIIQGEDYSITCEASGSPYPSIKWAKVHDFMPENVHISGNVLTIYGARFENRGVYSCVAENDHGSDLSSTSIDIEPRERPSVKIVSAPLQTFSVGAPASLYCTVEGIPDPTVEWVRVDGQPLSPRHKIQSPGYMVIDDIQLEDSGDYECRAKNIVGEATGVATITVQEPTLVQIIPDNRDLRLTEGDELSLTCVGSGVPNPEVEWVNEMALKRDLYSPPSNTAILKIYRVTKADAGIYTCHGKNEAGSDEAHVRVEVQERRGDIGGVDDDSDRDPINYNPPQQQNPGIHQPGSNQLLATDIGDNVTLTCDMFQPLNTRWERVDGAPLPRNAYTIKNRLEIVRVEQQNLGQYRCNGIGRDGNVKTYFVKELVLMPLPRIRFYPNIPLTVEAGQNLDVHCQVENVRPEDVHWSTDNNRPLPSSVRIVGSVLRFVSITQAAAGEYRCSAFNQYGNRSQIARVAVKKPADFHQVPQSQLQRHREGENIQLQCTVTDQYGVRAQDNVEFNWFRDDRRPLPNNARTDSQILVLTNLRPEDAGRYICNSYDVDRGQQLPEVSIDLQVLTATPPPNSPIYLPPQLPAKSRDYSLKLDDQSSNLRAGESTDVECYSSDDTYTDVVWERSDGAPLSNNVRQVGNRLVISNVSPSDAGNYVCKCKTDEGDLYTTSYKLEVEDQPHELKSSKIVYAKVGANADLQCGADESRQPTYRWSRQYGQLQAGRSLMNEKLSLDSVQANDAGTYICTAQYADGETADFPNILVVTGAIPQFRQEPRSYMSFPTLPNSSFKFNFELTFRPENGDGLLLFNGQTRGSGDYIALSLKDRYAEFRFDFGGKPMLVRAEEPLALNEWHTVRVSRFKRDGYIQVDEQHPVAFPTLQQIPQLDLIEDLYIGGVPNWELLPADAVSQQVGFVGCISRLTLQGRTVELIREAKYKEGITDCRPCAQGPCQNKGVCLESQTEQAYTCICQPGWTGRDCAIEGTQCTPGVCGAGRCENTENDMECLCPLNRSGDRCQYNEILNEHSLNFKGNSFAAYGTPKVTKVNITLSVRPASLEDSVILYTAESTLPSGDYLALVLRGGHAELLINTAARLDPVVVRSAEPLPLNRWTRIEIRRRLGEGILRVGDGPERKAKAPGSDRILSLKTHLYVGGYDRSTVKVNRDVNITKGFDGCISRLYNFQKPVNLLADIKDAANIQSCGETNMIGGDEDSDNEPPVPPPTPDVHENELQPYAMAPCASDPCENGGSCSEQEDVAVCSCPFGFSGKHCQEHLQLGFNASFRGDGYVELNRSHFQPALEQSYTSMGIVFTTNKPNGLLFWWGQEAGEEYTGQDFIAAAVVDGYVEYSMRLDGEEAVIRNSDIRVDNGERHIVIAKRDENTAILEVDRMLHSGETRPTSKKSMKLPGNVFVGGAPDLEVFTGFRYKHNLNGCIVVVEGETVGQINLSSAAVNGVNANVCPANDDPLGGTEPPVV", "length": 4150, "header": "tr|Q9W4Y4-1|A0ACD4DAU3_DROME Computationally mapped isoform of Terribly reduced optic lobes, isoform BD OS=Drosophila melanogaster OX=7227 GN=trol PE=1 SV=5 CANONICAL=A0ACD4DAU3-1" }, "locus": {} }, { "isoform_ac": "X2JAC7-1", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3/entry#X2JAC7-1", "sequence": { "sequence": "MMGSPGSQASAIATSVGIRSGRRGQAGGSLLLRLLAVTFVLAACHAPLLTNAKQISNLGDDQDFMLADDESLQGINDSEWQLMGDDIDDGLLDDVDETLKPMETKSEEEDLPTGNWFSQSVHRVRRSINRLFGSDDNQERGRRQQRERSQRNRDAINRQKELRRRQKEDHNRWKQMRMERQLEKQRLVKRTNHVVFNRATDPRKRASDLYDENEASGYHEEDTTLYRTYFVVNEPYDNEYRDRESVQFQNLQKLLDDDLRNFFHSNYEGNDDEEQEIRSTLERVEIELPTSVNDFGSKLQQQLNVYNRIENLSAATDGVFSFTESSVTEESVRHLDVGFVEPHITLFHEQNTGYDDFDRKPTTETQDIEEEAIDVTLPQEEVEGSGSDDSSCRGDATFTCPRSGKTICDEMRCDREIQCPDGEDEEYCNYPNVCTEDQFKCDDKCLELKKRCDGSIDCLDQTDEAGCINAPEPEPEPEPEPEPEPESEPEAEPEPEPEPEPESEPEQEPEPQVPEANECQANEFRCNNGDCIDARKRCNNVSDCSEGEDENEECRCYANQFRCNNGDCVSGSAPCNGYSECSDHSDELNCGGTQECLPNQFRCNSGQCVSSSVRCNGRTDCQDSSDEQNCAADSNDRRPNQLNLKTYPDSQIIKESREVIFRCRDEGPARAKVKWSRPGGRPLPPGFTDRNGRLEIPNIRVEDAGTYVCEAVGYASYIPGQQVTVNLNVERYNDVGSRPESACTEYQATCMNGECIDKSSICDGNPDCSDASDEQSCSLGLKCQPNQFMCSNSKCVDRTWRCDGENDCGDNSDETSCDPEPSGAPCRYNEFQCRSGHCIPKSFQCDNVPDCTDGTDEVGCMAPLPIRPPPQSVSLLEYEVLELTCVATGTPTPTIVWRLNWGHVPDKCESKSYGGTGTLRCPDMRPQDSGAYSCEIINTRGTHFVNPDTIVTVRPVRTDVCEAGFFNMLARKAEECVQCFCFGVAKACDSANLFTYAIHPPILSHRVVSVELSPLRQIVINEAAPGQDLLTLLHGVQFRATNVHFSGRETPYLALPADYMGNQLKSYGGNLRYEVNYRGSGRPVNGPDVIITGNRFTLTYRVRTQPGQNNRVSIPFVPGGWQKPDGRKASREEIMMILANVDNILIRLGYLDSTAREVDLINIALDSAGTADKGLGSASLVEKCQCPPGYVGDSCESCASGYVRQPGGPWLGHCVPFIPDSCPSGTYGDPRRGVPCKECPCPLTGSNNFASGCQQSPDGDVVCRCNEGYTGRRCEQCAAGYQGNPLAAGGICRRIPDTSCNVDGTYSVHSNGTCQCKDSVIGEQCDTCKSKSFHLNSFTYTGCIECFCSGVGLDCDSSTWYRDQVTSTFGRSRVDHGFVLVTNYMQPTPDTVPVSMAAEPNALSFIGSADQSGNTLYWSLPAAFLGNKLSSYGGKLTYTLSYSPLPNGIMSRNSAPDVVIKSGEDLRLIHYRKSQVVPSVANTYSVEIKESAWQRGDEVVANREHVLMALSDITAIYIKATYTTSTKEASLRQVTLDVATPTNLGTPRAVEVEQCRCPEGYLGLSCEQCAPGYARDPEGGIYLGLCRPCECNGHSKYCNSDTGDCEECSDNTEGPSCERCAAGYVGDATRGTIYDCQPDEGYPIPSPPAPGNQTLECTAYCQIEGIYDCRGNECLCKRNVIGDQCDQCRPGTYGLSAQNQDGCKECYCSGLASQCRSAALYRQLIPVDFILNAPLITDESGAVQDTENLIPDISRNMYTYTHTSYLPKYWSLRGSVLGNQLFSYGGRLSYSLIVESYGNYERGHDIVLIGNGLKLIWSRPDGNENQEEYNVRLHEDEQWTRQDRESARPASRSDFMTVLSDLQHILIRATPRVPTQSTSIGNVILESAVTTRTPGATHASDIELCQCPSGYVGTSCESCAPLHYRDASGSCSLCPCDVSNTESCDLVSGGYVECRCKARWKGDRCREIDTNDPTDIGTEDPVLTQIIVSIQKPEITIVPVGGSMTLSCSGRMRWSNSPVIVNWYKENSRLPENVEVQGGNLYLYDLQVSDSGVYICQAVNNETASVFKDTVSITITKKDQLSPAEIVNLPSHVTFEEYVNNEIICEVLGNPAPRVTWARVDGHADAQSTRTYDNRLIFDSPRKSDEGRYRCQAENDQNRDEKYVIVYVQSNPPQPPPQQDRLYITPEEINGLAGESFQLNCQFTSVASLRYDWSHNGRSLSSSPARNVEIRGNTLEVRDASESDSGVYTCVAYDVRTRRNFTESARVNIDRREEQPFGNKPIIESLEQNILIIQGEDYSITCEASGSPYPSIKWAKVHDFMPENVHISGNVLTIYGARFENRGVYSCVAENDHGSDLSSTSIDIEPRERPSVKIVSAPLQTFSVGAPASLYCTVEGIPDPTVEWVRVDGQPLSPRHKIQSPGYMVIDDIQLEDSGDYECRAKNIVGEATGVATITVQEPTLVQIIPDNRDLRLTEGDELSLTCVGSGVPNPEVEWVNEMALKRDLYSPPSNTAILKIYRVTKADAGIYTCHGKNEAGSDEAHVRVEVQERRGDIGGVDDDSDRDPINYNPPQQQNPGIHQPGSNQLLATDIGDNVTLTCDMFQPLNTRWERVDGAPLPRNAYTIKNRLEIVRVEQQNLGQYRCNGIGRDGNVKTYFVKELVLMPLPRIRFYPNIPLTVEAGQNLDVHCQVENVRPEDVHWSTDNNRPLPSSVRIVGSVLRFVSITQAAAGEYRCSAFNQYGNRSQIARVAVKKPADFHQVPQSQLQRHREGENIQLQCTVTDQYGVRAQDNVEFNWFRDDRRPLPNNARTDSQILVLTNLRPEDAGRYICNSYDVDRGQQLPEVSIDLQVLSE", "length": 2853, "header": "tr|X2JAC7-1|A0ACD4DAU3_DROME Computationally mapped isoform of Terribly reduced optic lobes, isoform BD OS=Drosophila melanogaster OX=7227 GN=trol PE=1 SV=1 CANONICAL=A0ACD4DAU3-1" }, "locus": {} }, { "isoform_ac": "X2JCE8-1", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3/entry#X2JCE8-1", "sequence": { "sequence": "MMGSPGSQASAIATSVGIRSGRRGQAGGSLLLRLLAVTFVLAACHAPLLTNAKQISNLGDDQDFMLADDESLQGINDSEWQLMGDDIDDGLLDDVDETLKPMETKSEEEDLPTGNWFSQSVHRVRRSINRLFGSDDNQERGRRQQRERSQRNRDAINRQKELRRRQKEDHNRWKQMRMERQLEKQRLVKRTNHVVFNRATDPRKRASDLYDENEASGYHEEDTTLYRTYFVVNEPYDNEYRDRESVQFQNLQKLLDDDLRNFFHSNYEGNDDEEQEIRSTLERVEPTNDNFKIRVQLRIELPTSVNDFGSKLQQQLNVYNRIENLSAATDGVFSFTESSDIEEEAIDVTLPQEEVEGSGSDDSSCRGDATFTCPRSGKTICDEMRCDREIQCPDGEDEEYCNYPNVCTEDQFKCDDKCLELKKRCDGSIDCLDQTDEAGCINAPEPEPEPEPEPEPEPESEPEAEPEPEPEPEPESEPEQEPEPQVPEANECQANEFRCNNGDCIDARKRCNNVSDCSEGEDENEECPAACSGMEYQCRDGTRCISVSQQCDGHSDCSDGDDEEHCDGSGYDSEECRFDEFHCGTGECIPMRQVCDNIYDCNDYSDEVNCVEGEEEDRVGIPIGHQPWRPASKHDDWLHEMDTSEYQVYQPSNVYEKANSQNPCASNQFRCTTSNVCIPLHLRCDGFYHCNDMSDEKSCEQYQRHTTTRRPLTLATPTSRITTQGPGLLERRNTTTATEASRWPWATKTTTIATTTSNPITTVGVANSPPQTCLENIEFACHNRDCISIESVCDGIPDCGRNEDEDDALCKCSGDKYKCQRGGGCIPKSQVCDGKPQCHDRSDESACPTTRLKPSDCSPEQFYCDESCYNRSVRCNGHVDCSDGSDEVGCSLPCPQHQCPSGRCYTESERCDRHRHCEDGSDEANCCYANQFRCNNGDCVSGSAPCNGYSECSDHSDELNCGGTQECLPNQFRCNSGQCVSSSVRCNGRTDCQDSSDEQNCGHRHTEVSQGLETTGVFTTSTTSTTAMTPLRIICPPTSFKCENGPCISLGLKCNGRVDCPYDGSDEADCGQISNDIDPADSNDRRPNQLNLKTYPDSQIIKESREVIFRCRDEGPARAKVKWSRPGGRPLPPGFTDRNGRLEIPNIRVEDAGTYVCEAVGYASYIPGQQVTVNLNVERYNDVGSRPESACTEYQATCMNGECIDKSSICDGNPDCSDASDEQSCSLGLKCQPNQFMCSNSKCVDRTWRCDGENDCGDNSDETSCDPEPSGAPCRYNEFQCRSGHCIPKSFQCDNVPDCTDGTDEVGCMAPLPIRPPPQSVSLLEYEVLELTCVATGTPTPTIVWRLNWGHVPDKCESKSYGGTGTLRCPDMRPQDSGAYSCEIINTRGTHFVNPDTIVTVRPVRTDVCEAGFFNMLARKAEECVQCFCFGVAKACDSANLFTYAIHPPILSHRVVSVELSPLRQIVINEAAPGQDLLTLLHGVQFRATNVHFSGRETPYLALPADYMGNQLKSYGGNLRYEVNYRGSGRPVNGPDVIITGNRFTLTYRVRTQPGQNNRVSIPFVPGGWQKPDGRKASREEIMMILANVDNILIRLGYLDSTAREVDLINIALDSAGTADKGLGSASLVEKCQCPPGYVGDSCESCASGYVRQPGGPWLGHCVPFIPDSCPSGTYGDPRRGVPCKECPCPLTGSNNFASGCQQSPDGDVVCRCNEGYTGRRCEQCAAGYQGNPLAAGGICRRIPDTSCNVDGTYSVHSNGTCQCKDSVIGEQCDTCKSKSFHLNSFTYTGCIECFCSGVGLDCDSSTWYRDQVTSTFGRSRVDHGFVLVTNYMQPTPDTVPVSMAAEPNALSFIGSADQSGNTLYWSLPAAFLGNKLSSYGGKLTYTLSYSPLPNGIMSRNSAPDVVIKSGEDLRLIHYRKSQVVPSVANTYSVEIKESAWQRGDEVVANREHVLMALSDITAIYIKATYTTSTKEASLRQVTLDVATPTNLGTPRAVEVEQCRCPEGYLGLSCEQCAPGYARDPEGGIYLGLCRPCECNGHSKYCNSDTGDCEECSDNTEGPSCERCAAGYVGDATRGTIYDCQPDEGYPIPSPPAPGNQTLECTAYCQIEGIYDCRGNECLCKRNVIGDQCDQCRPGTYGLSAQNQDGCKECYCSGLASQCRSAALYRQLIPVDFILNAPLITDESGAVQDTENLIPDISRNMYTYTHTSYLPKYWSLRGSVLGNQLFSYGGRLSYSLIVESYGNYERGHDIVLIGNGLKLIWSRPDGNENQEEYNVRLHEDEQWTRQDRESARPASRSDFMTVLSDLQHILIRATPRVPTQSTSIGNVILESAVTTRTPGATHASDIELCQCPSGYVGTSCESCAPLHYRDASGSCSLCPCDVSNTESCDLVSGGYVECRCKARWKGDRCREIDTNDPTDIGTEDPVLTQIIVSIQKPEITIVPVGGSMTLSCSGRMRWSNSPVIVNWYKENSRLPENVEVQGGNLYLYDLQVSDSGVYICQAVNNETASVFKDTVSITITKKDQLSPAEIVNLPSHVTFEEYVNNEIICEVLGNPAPRVTWARVDGHADAQSTRTYDNRLIFDSPRKSDEGRYRCQAENDQNRDEKYVIVYVQSNPPQPPPQQDRLYITPEEINGLAGESFQLNCQFTSVASLRYDWSHNGRSLSSSPARNVEIRGNTLEVRDASESDSGVYTCVAYDVRTRRNFTESARVNIDRREEQPFGNKPIIESLEQNILIIQGEDYSITCEASGSPYPSIKWAKVHDFMPENVHISGNVLTIYGARFENRGVYSCVAENDHGSDLSSTSIDIEPRERPSVKIVSAPLQTFSVGAPASLYCTVEGIPDPTVEWVRVDGQPLSPRHKIQSPGYMVIDDIQLEDSGDYECRAKNIVGEATGVATITVQEPTLVQIIPDNRDLRLTEGDELSLTCVGSGVPNPEVEWVNEMALKRDLYSPPSNTAILKIYRVTKADAGIYTCHGKNEAGSDEAHVRVEVQERRGDIGGVDDDSDRDPINYNPPQQQNPGIHQPGSNQLLATDIGDNVTLTCDMFQPLNTRWERVDGAPLPRNAYTIKNRLEIVRVEQQNLGQYRCNGIGRDGNVKTYFVKELVLMPLPRIRFYPNIPLTVEAGQNLDVHCQVENVRPEDVHWSTDNNRPLPSSVRIVGSVLRFVSITQAAAGEYRCSAFNQYGNRSQIARVAVKKPADFHQVPQSQLQRHREGENIQLQCTVTDQYGVRAQDNVEFNWFRDDRRPLPNNARTDSQILVLTNLRPEDAGRYICNSYDVDRGQQLPEVSIDLQVLTATPPPNSPIYLPPQLPAKSRDYSLKLDDQSSNLRAGESTDVECYSSDDTYTDVVWERSDGAPLSNNVRQVGNRLVISNVSPSDAGNYVCKCKTDEGDLYTTSYKLEVEDQPHELKSSKIVYAKVGANADLQCGADESRQPTYRWSRQYGQLQAGRSLMNEKLSLDSVQANDAGTYICTAQYADGETADFPNILVVTGAIPQFRQEPRSYMSFPTLPNSSFKFNFELTFRPENGDGLLLFNGQTRGSGDYIALSLKDRYAEFRFDFGGKPMLVRAEEPLALNEWHTVRVSRFKRDGYIQVDEQHPVAFPTLQQIPQLDLIEDLYIGGVPNWELLPADAVSQQVGFVGCISRLTLQGRTVELIREAKYKEGITDCRPCAQGPCQNKGVCLESQTEQAYTCICQPGWTGRDCAIEGTQCTPGVCGAGRCENTENDMECLCPLNRSGDRCQYNEILNEHSLNFKGNSFAAYGTPKVTKVNITLSVRPASLEDSVILYTAESTLPSGDYLALVLRGGHAELLINTAARLDPVVVRSAEPLPLNRWTRIEIRRRLGEGILRVGDGPERKAKAPGSDRILSLKTHLYVGGYDRSTVKVNRDVNITKGFDGCISRLYNFQKPVNLLADIKDAANIQSCGETNMIGGDEDSDNEPPVPPPTPDVHENELQPYAMAPCASDPCENGGSCSEQEDVAVCSCPFGFSGKHCQEHLQLGFNASFRGDGYVELNRSHFQPALEQSYTSMGIVFTTNKPNGLLFWWGQEAGEEYTGQDFIAAAVVDGYVEYSMRLDGEEAVIRNSDIRVDNGERHIVIAKRDENTAILEVDRMLHSGETRPTSKKSMKLPGNVFVGGAPDLEVFTGFRYKHNLNGCIVVVEGETVGQINLSSAAVNGVNANVCPANDDPLGGTEPPVV", "length": 4203, "header": "tr|X2JCE8-1|A0ACD4DAU3_DROME Computationally mapped isoform of Terribly reduced optic lobes, isoform BD OS=Drosophila melanogaster OX=7227 GN=trol PE=1 SV=1 CANONICAL=A0ACD4DAU3-1" }, "locus": {} }, { "isoform_ac": "X2JDK9-1", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3/entry#X2JDK9-1", "sequence": { "sequence": "MMGSPGSQASAIATSVGIRSGRRGQAGGSLLLRLLAVTFVLAACHAPLLTNAKQISNLGDDQDFMLADDESLQGINDSEWQLMGDDIDDGLLDDVDETLKPMETKSEEEDLPTGNWFSQSVHRVRRSINRLFGSDDNQERGRRQQRERSQRNRDAINRQKELRRRQKEDHNRWKQMRMERQLEKQRLVKRTNHVVFNRATDPRKRASDLYDENEASGYHEEDTTLYRTYFVVNEPYDNEYRDRESVQFQNLQKLLDDDLRNFFHSNYEGNDDEEQEIRSTLERVEPTNDNFKIRVQLRIELPTSVNDFGSKLQQQLNVYNRIENLSAATDGVFSFTESSDIEEEAIDVTLPQEEVEGSGSDDSSCRGDATFTCPRSGKTICDEMRCDREIQCPDGEDEEYCNYPNVCTEDQFKCDDKCLELKKRCDGSIDCLDQTDEAGCINAPEPEPEPEPEPEPEPESEPEAEPEPEPEPEPESEPEQEPEPQVPEANECQANEFRCNNGDCIDARKRCNNVSDCSEGEDENEECRCYANQFRCNNGDCVSGSAPCNGYSECSDHSDELNCGGTQECLPNQFRCNSGQCVSSSVRCNGRTDCQDSSDEQNCGHRHTEVSQGLETTGVFTTSTTSTTAMTPLRIICPPTSFKCENGPCISLGLKCNGRVDCPYDGSDEADCGQISNDIDPADSNDRRPNQLNLKTYPDSQIIKESREVIFRCRDEGPARAKVKWSRPGGRPLPPGFTDRNGRLEIPNIRVEDAGTYVCEAVGYASYIPGQQVTVNLNVERYNDVGSRPESACTEYQATCMNGECIDKSSICDGNPDCSDASDEQSCSLGLKCQPNQFMCSNSKCVDRTWRCDGENDCGDNSDETSCDPEPSGAPCRYNEFQCRSGHCIPKSFQCDNVPDCTDGTDEVGCMAPLPIRPPPQSVSLLEYEVLELTCVATGTPTPTIVWRLNWGHVPDKCESKSYGGTGTLRCPDMRPQDSGAYSCEIINTRGTHFVNPDTIVTVRPVRTDVCEAGFFNMLARKAEECVQCFCFGVAKACDSANLFTYAIHPPILSHRVVSVELSPLRQIVINEAAPGQDLLTLLHGVQFRATNVHFSGRETPYLALPADYMGNQLKSYGGNLRYEVNYRGSGRPVNGPDVIITGNRFTLTYRVRTQPGQNNRVSIPFVPGGWQKPDGRKASREEIMMILANVDNILIRLGYLDSTAREVDLINIALDSAGTADKGLGSASLVEKCQCPPGYVGDSCESCASGYVRQPGGPWLGHCVPFIPDSCPSGTYGDPRRGVPCKECPCPLTGSNNFASGCQQSPDGDVVCRCNEGYTGRRCEQCAAGYQGNPLAAGGICRRIPDTSCNVDGTYSVHSNGTCQCKDSVIGEQCDTCKSKSFHLNSFTYTGCIECFCSGVGLDCDSSTWYRDQVTSTFGRSRVDHGFVLVTNYMQPTPDTVPVSMAAEPNALSFIGSADQSGNTLYWSLPAAFLGNKLSSYGGKLTYTLSYSPLPNGIMSRNSAPDVVIKSGEDLRLIHYRKSQVVPSVANTYSVEIKESAWQRGDEVVANREHVLMALSDITAIYIKATYTTSTKEASLRQVTLDVATPTNLGTPRAVEVEQCRCPEGYLGLSCEQCAPGYARDPEGGIYLGLCRPCECNGHSKYCNSDTGDCEECSDNTEGPSCERCAAGYVGDATRGTIYDCQPDEGYPIPSPPAPGNQTLECTAYCQIEGIYDCRGNECLCKRNVIGDQCDQCRPGTYGLSAQNQDGCKECYCSGLASQCRSAALYRQLIPVDFILNAPLITDESGAVQDTENLIPDISRNMYTYTHTSYLPKYWSLRGSVLGNQLFSYGGRLSYSLIVESYGNYERGHDIVLIGNGLKLIWSRPDGNENQEEYNVRLHEDEQWTRQDRESARPASRSDFMTVLSDLQHILIRATPRVPTQSTSIGNVILESAVTTRTPGATHASDIELCQCPSGYVGTSCESCAPLHYRDASGSCSLCPCDVSNTESCDLVSGGYVECRCKARWKGDRCREIDTNDPTDIGTEDPVLTQIIVSIQKPEITIVPVGGSMTLSCSGRMRWSNSPVIVNWYKENSRLPENVEVQGGNLYLYDLQVSDSGVYICQAVNNETASVFKDTVSITITKKDQLSPAEIVNLPSHVTFEEYVNNEIICEVLGNPAPRVTWARVDGHADAQSTRTYDNRLIFDSPRKSDEGRYRCQAENDQNRDEKYVIVYVQSNPPQPPPQQDRLYITPEEINGLAGESFQLNCQFTSVASLRYDWSHNGRSLSSSPARNVEIRGNTLEVRDASESDSGVYTCVAYDVRTRRNFTESARVNIDRREEQPFGNKPIIESLEQNILIIQGEDYSITCEASGSPYPSIKWAKVHDFMPENVHISGNVLTIYGARFENRGVYSCVAENDHGSDLSSTSIDIEPRERPSVKIVSAPLQTFSVGAPASLYCTVEGIPDPTVEWVRVDGQPLSPRHKIQSPGYMVIDDIQLEDSGDYECRAKNIVGEATGVATITVQEPTLVQIIPDNRDLRLTEGDELSLTCVGSGVPNPEVEWVNEMALKRDLYSPPSNTAILKIYRVTKADAGIYTCHGKNEAGSDEAHVRVEVQERRGDIGGVDDDSDRDPINYNPPQQQNPGIHQPGSNQLLATDIGDNVTLTCDMFQPLNTRWERVDGAPLPRNAYTIKNRLEIVRVEQQNLGQYRCNGIGRDGNVKTYFVKELVLMPLPRIRFYPNIPLTVEAGQNLDVHCQVENVRPEDVHWSTDNNRPLPSSVRIVGSVLRFVSITQAAAGEYRCSAFNQYGNRSQIARVAVKKPADFHQVPQSQLQRHREGENIQLQCTVTDQYGVRAQDNVEFNWFRDDRRPLPNNARTDSQILVLTNLRPEDAGRYICNSYDVDRGQQLPEVSIDLQVLTATPPPNSPIYLPPQLPAKSRDYSLKLDDQSSNLRAGESTDVECYSSDDTYTDVVWERSDGAPLSNNVRQVGNRLVISNVSPSDAGNYVCKCKTDEGDLYTTSYKLEVEDQPHELKSSKIVYAKVGANADLQCGADESRQPTYRWSRQYGQLQAGRSLMNEKLSLDSVQANDAGTYICTAQYADGETADFPNILVVTGAIPQFRQEPRSYMSFPTLPNSSFKFNFELTFRPENGDGLLLFNGQTRGSGDYIALSLKDRYAEFRFDFGGKPMLVRAEEPLALNEWHTVRVSRFKRDGYIQVDEQHPVAFPTLQQIPQLDLIEDLYIGGVPNWELLPADAVSQQVGFVGCISRLTLQGRTVELIREAKYKEGITDCRPCAQGPCQNKGVCLESQTEQAYTCICQPGWTGRDCAIEGTQCTPGVCGAGRCENTENDMECLCPLNRSGDRCQYNEILNEHSLNFKGNSFAAYGTPKVTKVNITLSVRPASLEDSVILYTAESTLPSGDYLALVLRGGHAELLINTAARLDPVVVRSAEPLPLNRWTRIEIRRRLGEGILRVGDGPERKAKAPGSDRILSLKTHLYVGGYDRSTVKVNRDVNITKGFDGCISRLYNFQKPVNLLADIKDAANIQSCGETNMIGGDEDSDNEPPVPPPTPDVHENELQPYAMAPCASDPCENGGSCSEQEDVAVCSCPFGFSGKHCQEHLQLGFNASFRGDGYVELNRSHFQPALEQSYTSMGIVFTTNKPNGLLFWWGQEAGEEYTGQDFIAAAVVDGYVEYSMRLDGEEAVIRNSDIRVDNGERHIVIAKRDENTAILEVDRMLHSGETRPTSKKSMKLPGNVFVGGAPDLEVFTGFRYKHNLNGCIVVVEGETVGQINLSSAAVNGVNANVCPANDDPLGGTEPPVV", "length": 3805, "header": "tr|X2JDK9-1|A0ACD4DAU3_DROME Computationally mapped isoform of Terribly reduced optic lobes, isoform BD OS=Drosophila melanogaster OX=7227 GN=trol PE=1 SV=1 CANONICAL=A0ACD4DAU3-1" }, "locus": {} }, { "isoform_ac": "X2JE09-1", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3/entry#X2JE09-1", "sequence": { "sequence": "MMGSPGSQASAIATSVGIRSGRRGQAGGSLLLRLLAVTFVLAACHAPLLTNAKQISNLGDDQDFMLADDESLQGINDSEWQLMGDDIDDGLLDDVDETLKPMETKSEEEDLPTGNWFSQSVHRVRRSINRLFGSDDNQERGRRQQRERSQRNRDAINRQKELRRRQKEDHNRWKQMRMERQLEKQRLVKRTNHVVFNRATDPRKRASDLYDENEASGYHEEDTTLYRTYFVVNEPYDNEYRDRESVQFQNLQKLLDDDLRNFFHSNYEGNDDEEQEIRSTLERVEIELPTSVNDFGSKLQQQLNVYNRIENLSAATDGVFSFTESSVTEESVRHLDVGFVEPHITLFHEQNTGYDDFDRKPTTETQDIEEEAIDVTLPQEEVEGSGSDDSSCRGDATFTCPRSGKTICDEMRCDREIQCPDGEDEEYCNYPNVCTEDQFKCDDKCLELKKRCDGSIDCLDQTDEAGCINAPEPEPEPEPEPEPEPESEPEAEPEPEPEPEPESEPEQEPEPQVPEANECQANEFRCNNGDCIDARKRCNNVSDCSEGEDENEECLEGEEEDRVGIPIGHQPWRPASKHDDWLHEMDTSEYQVYQPSNVYEKANSQNPCASNQFRCTTSNVCIPLHLRCDGFYHCNDMSDEKSCEQYQRHTTTRRPLTLATPTSRITTQGPGLLERRNTTTATEASRWPWATKTTTIATTTSNPITTVGVASCYANQFRCNNGDCVSGSAPCNGYSECSDHSDELNCGGTQECLPNQFRCNSGQCVSSSVRCNGRTDCQDSSDEQNCAADSNDRRPNQLNLKTYPDSQIIKESREVIFRCRDEGPARAKVKWSRPGGRPLPPGFTDRNGRLEIPNIRVEDAGTYVCEAVGYASYIPGQQVTVNLNVERYNDVGSRPESACTEYQATCMNGECIDKSSICDGNPDCSDASDEQSCSLGLKCQPNQFMCSNSKCVDRTWRCDGENDCGDNSDETSCDPEPSGAPCRYNEFQCRSGHCIPKSFQCDNVPDCTDGTDEVGCMAPLPIRPPPQSVSLLEYEVLELTCVATGTPTPTIVWRLNWGHVPDKCESKSYGGTGTLRCPDMRPQDSGAYSCEIINTRGTHFVNPDTIVTVRPVRTDVCEAGFFNMLARKAEECVQCFCFGVAKACDSANLFTYAIHPPILSHRVVSVELSPLRQIVINEAAPGQDLLTLLHGVQFRATNVHFSGRETPYLALPADYMGNQLKSYGGNLRYEVNYRGSGRPVNGPDVIITGNRFTLTYRVRTQPGQNNRVSIPFVPGGWQKPDGRKASREEIMMILANVDNILIRLGYLDSTAREVDLINIALDSAGTADKGLGSASLVEKCQCPPGYVGDSCESCASGYVRQPGGPWLGHCVPFIPDSCPSGTYGDPRRGVPCKECPCPLTGSNNFASGCQQSPDGDVVCRCNEGYTGRRCEQCAAGYQGNPLAAGGICRRIPDTSCNVDGTYSVHSNGTCQCKDSVIGEQCDTCKSKSFHLNSFTYTGCIECFCSGVGLDCDSSTWYRDQVTSTFGRSRVDHGFVLVTNYMQPTPDTVPVSMAAEPNALSFIGSADQSGNTLYWSLPAAFLGNKLSSYGGKLTYTLSYSPLPNGIMSRNSAPDVVIKSGEDLRLIHYRKSQVVPSVANTYSVEIKESAWQRGDEVVANREHVLMALSDITAIYIKATYTTSTKEASLRQVTLDVATPTNLGTPRAVEVEQCRCPEGYLGLSCEQCAPGYARDPEGGIYLGLCRPCECNGHSKYCNSDTGDCEECSDNTEGPSCERCAAGYVGDATRGTIYDCQPDEGYPIPSPPAPGNQTLECTAYCQIEGIYDCRGNECLCKRNVIGDQCDQCRPGTYGLSAQNQDGCKECYCSGLASQCRSAALYRQLIPVDFILNAPLITDESGAVQDTENLIPDISRNMYTYTHTSYLPKYWSLRGSVLGNQLFSYGGRLSYSLIVESYGNYERGHDIVLIGNGLKLIWSRPDGNENQEEYNVRLHEDEQWTRQDRESARPASRSDFMTVLSDLQHILIRATPRVPTQSTSIGNVILESAVTTRTPGATHASDIELCQCPSGYVGTSCESCAPLHYRDASGSCSLCPCDVSNTESCDLVSGGYVECRCKARWKGDRCREIDTSPIIEDPPQICDLSRGFCCSGFQFDIAPNETISFNDTLQIYKGNRIIGNMTKLRYGCPSRDTNDPTDIGTEDPVLTQIIVSIQKPEITIVPVGGSMTLSCSGRMRWSNSPVIVNWYKENSRLPENVEVQGGNLYLYDLQVSDSGVYICQAVNNETASVFKDTVSITITKKDQLSPAEIVNLPSHVTFEEYVNNEIICEVLGNPAPRVTWARVDGHADAQSTRTYDNRLIFDSPRKSDEGRYRCQAENDQNRDEKYVIVYVQSNPPQPPPQQDRLYITPEEINGLAGESFQLNCQFTSVASLRYDWSHNGRSLSSSPARNVEIRGNTLEVRDASESDSGVYTCVAYDVRTRRNFTESARVNIDRREEQPFGNKPIIESLEQNILIIQGEDYSITCEASGSPYPSIKWAKVHDFMPENVHISGNVLTIYGARFENRGVYSCVAENDHGSDLSSTSIDIEPRERPSVKIVSAPLQTFSVGAPASLYCTVEGIPDPTVEWVRVDGQPLSPRHKIQSPGYMVIDDIQLEDSGDYECRAKNIVGEATGVATITVQEPTLVQIIPDNRDLRLTEGDELSLTCVGSGVPNPEVEWVNEMALKRDLYSPPSNTAILKIYRVTKADAGIYTCHGKNEAGSDEAHVRVEVQERRGDIGGVDDDSDRDPINYNPPQQQNPGIHQPGSNQLLATDIGDNVTLTCDMFQPLNTRWERVDGAPLPRNAYTIKNRLEIVRVEQQNLGQYRCNGIGRDGNVKTYFVKELVLMPLPRIRFYPNIPLTVEAGQNLDVHCQVENVRPEDVHWSTDNNRPLPSSVRIVGSVLRFVSITQAAAGEYRCSAFNQYGNRSQIARVAVKKPADFHQVPQSQLQRHREGENIQLQCTVTDQYGVRAQDNVEFNWFRDDRRPLPNNARTDSQILVLTNLRPEDAGRYICNSYDVDRGQQLPEVSIDLQVLTATPPPNSPIYLPPQLPAKSRDYSLKLDDQSSNLRAGESTDVECYSSDDTYTDVVWERSDGAPLSNNVRQVGNRLVISNVSPSDAGNYVCKCKTDEGDLYTTSYKLEVEDQPHELKSSKIVYAKVGANADLQCGADESRQPTYRWSRQYGQLQAGRSLMNEKLSLDSVQANDAGTYICTAQYADGETADFPNILVVTGAIPQFRQEPRSYMSFPTLPNSSFKFNFELTFRPENGDGLLLFNGQTRGSGDYIALSLKDRYAEFRFDFGGKPMLVRAEEPLALNEWHTVRVSRFKRDGYIQVDEQHPVAFPTLQQIPQLDLIEDLYIGGVPNWELLPADAVSQQVGFVGCISRLTLQGRTVELIREAKYKEGITDCRPCAQGPCQNKGVCLESQTEQAYTCICQPGWTGRDCAIEGTQCTPGVCGAGRCENTENDMECLCPLNRSGDRCQYNEILNEHSLNFKGNSFAAYGTPKVTKVNITLSVRPASLEDSVILYTAESTLPSGDYLALVLRGGHAELLINTAARLDPVVVRSAEPLPLNRWTRIEIRRRLGEGILRVGDGPERKAKAPGSDRILSLKTHLYVGGYDRSTVKVNRDVNITKGFDGCISRLYNFQKPVNLLADIKDAANIQSCGETNMIGGDEDSDNEPPVPPPTPDVHENELQPYAMAPCASDPCENGGSCSEQEDVAVCSCPFGFSGKHCQEHLQLGFNASFRGDGYVELNRSHFQPALEQSYTSMGIVFTTNKPNGLLFWWGQEAGEEYTGQDFIAAAVVDGYVEYSMRLDGEEAVIRNSDIRVDNGERHIVIAKRDENTAILEVDRMLHSGETRPTSKKSMKLPGNVFVGGAPDLEVFTGFRYKHNLNGCIVVVEGETVGQINLSSAAVNGVNANVCPANDDPLGGTEPPVV", "length": 3973, "header": "tr|X2JE09-1|A0ACD4DAU3_DROME Computationally mapped isoform of Terribly reduced optic lobes, isoform BD OS=Drosophila melanogaster OX=7227 GN=trol PE=1 SV=1 CANONICAL=A0ACD4DAU3-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2084, "start_aa": "Thr", "end_pos": 2084, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2084", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 4238, "start_aa": "Thr", "end_pos": 4238, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr4238", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q8IRV9", "url": "https://www.uniprot.org/uniprotkb/Q8IRV9" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q8IRV9", "url": "https://www.uniprot.org/uniprotkb/Q8IRV9" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q8IRV9", "url": "https://www.uniprot.org/uniprotkb/Q8IRV9" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q8IRV9", "url": "https://www.uniprot.org/uniprotkb/Q8IRV9" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q8IRV9", "url": "https://www.uniprot.org/uniprotkb/Q8IRV9" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q8IRV9", "url": "https://www.uniprot.org/uniprotkb/Q8IRV9" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q8IRV9", "url": "https://www.uniprot.org/uniprotkb/Q8IRV9" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q8IRV9", "url": "https://www.uniprot.org/uniprotkb/Q8IRV9" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q8IRV9", "url": "https://www.uniprot.org/uniprotkb/Q8IRV9" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q8IRV9", "url": "https://www.uniprot.org/uniprotkb/Q8IRV9" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q8IRV9", "url": "https://www.uniprot.org/uniprotkb/Q8IRV9" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG33950", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG33950", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6ASH2-1", "protein_name": "Basement membrane-specific heparan sulfate proteoglycan core protein", "gene_name": "Hspg2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQRAVGSLLLGLLLHARLLAVTQGLRAYDGLSLPEDTETVTASRYGWTYSYLSDDEDLLADDASGDGLGSGDLGSGDFQMVYFRALVNFTRSIEYSPQLEDANAKEFREVSEAVVEKLETEYVKIPGDQIVSVVFIKELDGWVFVELDVGSEGNADGSQIQEVLHTVVSSGSIGPYVTSPWGFKFRRLGTVPQFPRVCTETEFACHSYNECVALEYRCDRRPDCRDMSDELNCEEAVSEISSLPSAVVKVSPLPLWPEAATLPPPVMHGPQFLLPNVPGPTACGPQEASCHSGHCIPRDYLCDGQEDCRDGSDELGCGPPPPCEPNEFSCENGHCALKLWRCDGDFDCEDHTDEANCPVKHPGEVCGPTQFQCVSTNRCIPASFHCDEETDCPDRSDEFGCMPPQVVTPPQQSIQASRGQTVTFTCVATGVPTPIINWRLNWGHIPVNPRVTMTSEGGRGTLIIRDVKEADQGAYTCEAMNSRGMVFGIPDGVLELVPQRGPCPDGHFYLEDSASCLPCFCFGVTNLCQSSRRFRDQIRLNFDQPSDFKGVNVTMPSQPGVPPLSSTQLQIDPTLQEFQLVDLSRRFLVHDAFWALPKQFLGNKVDSYGGFLRYKVRYELARGMLEPVQKPDVILVGAGYRLHSRGHTPTHPGALNQRQVQLSEEHWVHESGRPVQRAEMLQALASLEAVLLQTVYNTKMTSVGLSDIVMDTTVTYTTIHGRAHSVEECRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCNCNGHASSCDPVYGHCLNCQHNTEGPQCDKCKPGFFGDATKATATACRPCPCPYIDASQRFSDTCFLDTDGQATCDACAPGYTGRRCESCAPGYEGNPIQPGGKCRPSNQELVRCDERGSLSATGEACRCKNNVVGRSCNECSEGSFHLSKQNPDGCLKCFCMGVSRQCSSSSWSRAQVLGASVQPSQFTLTNAAGTHTTSEGVSSPAPGELLFSSFHNLLSEPYFWSLPASFRGDKVTSYGGELRFTVTQRPRPGSAPLHRQPLVVLQGNNIVLEHHASREPSPGQPSNFIVPFQEQVWQRPDGQPATREHLLMALAGIDALLIQASHTQQPAESRLSGISMDVAVPENTGQDPAREVEHCTCPPGYRGPSCQDCDTGYTRVASGLYLGTCERCNCHGHSETCEPETGACQSCQHHTEGASCEQCQPGYYGDPQRGTPQDCQPCPCYGTPAAGQASHTCFLDTDGHPTCDSCSPGHSGRHCERCAPGYHGNPSQGQPCHRDGQVPEVPGCDCDPHGSISSQCDATGQCQCKAQVEGRTCSHCRPHHFHLSASNPEGCLPCFCMGVTQQCTSSSYSRQLISTHFAPGDFQGFALVNPQRNSQLTGGFTVEPVPDGARLSFSNFAHLGQESFYWQLPETYQGDKVAAYGGKLRYTLSYTSGPQGSPLSDPDIQITGNNIMLVASQPALQGPERRSYEIIFREEFWRRPDGQPATREHLLMALADLDELLVRATFSSVPRAASISAVSLEVAQPGPSGGPQALEVEECRCPPGYVGLSCQDCAPGYTRTGSGLYLGQCELCECNGHSEVCHPETGACTGCQHNTVGEFCETCATGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGYTGQYCEQCAPGYEGNPNVQGGRCQPLTKESLEVQIHPSRSVVPQGGPHSLRCQVNGSPPHYFYWSREDGRPLPSGAQQRHQGSELHFPSVQPSDAGVYICTCRNLIHTSNSRAELLVAEAPSKPITVTVEEQRSQSVRPGADVTFICTAKSKSPAYTLVWTRLHNGKLPSRAMDFNGILTIRNVQPSDAGTYVCTGSNMFAMDQGTATLHVQVSGTSTAPVASIHPPQLTVQPGQLAEFRCSATGNPTPTLEWIGGPSGQLPTKAQIHNGILRLPAIEPSDQGQYLCRALSSAGQHVVRAMLQVHGGSGPRVQVSPERTQVHEGRTVRLYCRAAGVPSASITWRKEGGSLPPQARSENTDIPTLLIPAIRVADSGFYLCVATSPTGTAQARIQVVVLSASGASSVPVRIESSSPSVTEGQTLDLNCAVMGLTYTQVTWYKRGGSLPPHAQVHGSRLRLPQVSPADSGEYVCRVESDLGPKEASIVVSVLHSPHSGPSYTPATSSTPPIRIESSSSHVAEGQTLDLNCVVPGQAQVTWRKRGGSLPARHQTHGSLLRLHQVSPADSGEYVCHVLLGSEHIETSVLVAIEPAVSIPAPGPVPPVRIESSSPTVAEGQTLDLNCVVAGQAHAQVTWYKRGSSLPARHQVRGSRLYIFQASPADAGEYVCRAGNGQEATITVKVTGNQGANIAYPPGSTPTIRIESSSSHVAEGQTLDLNCVVQGQAHAQVTWHKRGGSLPARHQTHGSLLRLHQVSPVDSGEYVCRVEGGPVPLESSVLVAIEPAGSVPALGVTPPVRIESSSSHVSEGQSLDLNCLVAGQTHPQISWHKRGGSLPARHQVHGSRLRLLQVTPADSGEYVCRVVSGSGTHEASVLVTIQQHLSPSHPQSVVHPVRIESSSPSLANGHTLDLNCLVASLTPHTITWYKRGGSLPSRHQIVGSRLRIPQVTPADSGEYVCHVSNGVGSQETSLIVTIESRGPSHVPSVSPPMRIETSSPTVTEGQTLDLNCVVVGRPQATITWYKRGGSLPFRHQAHGSRLRLHQMSVADSGEYVCRANNNIDAQETSIMISVSPNTNAPSASASPVPIRIESSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGGSLPAHHQAHGSRLRLYQVSPADSGEYVCRVLSSSGPLEASVLVSITASASNVHVPGENPFPPIRIETSSSQVAEGQTLDLTCVVPGQAHAQVTWHKRGGSLPAGHQVHGHILRLNRVSPADSGEYSCQVTGSSGTLEASVLVTIEASQPSPIPAPGLAQPIYIESSSSHLAEGQTVDLNCVVPGQAHAQVTWHKRGSSLPARHQTHGSLLRLYHISPADSGEYVCQVAGSSHPEHEASFKITVPASEGSSYRLRSPVISIEPPSSTVQQGQDASFKCLIHEGATPISLEWKTRNQELEDNVHISPNGSIMTIVGARPSNHGAYRCVASNVYGVAQSVVNLIVHGPPTVSVLPEGPVHVKMGKDITLECVSSGEPRSSPRWTRLGIPVKLEPRMFGLMNSHAMLKIASVKPSDAGTYVCQAQNALGTAQKQVELIVDTGTVAPGAPQVQVEEAELTLEAGHTATLHCSATGNPPPTIHWSKLRAPLPWQHRIEGNTLVIPRVAQQDSGQYICNATNSAGHTEATVVLHVESHPYATIIPEHTSVQPGKLVQLQCLAHGTPPLTYQWSRVGGILPEKAVARNQLLRLEPAGRADSGRYRCQVSNKVGSAEAFAQVLVQGSSGDVPDTSTPVGSTPTVQVTPQQETKSIGASVEFHCAVPNEHGTHLRWLKEGGQLPPGHSVQDGVLRIQNLDQSCQGTYICQAHGPWGQAQATAQLIVQALPSVLINVRTSVHSVVVGHSVEFECLALGDPKPQVTWSKVGGRLRSGIVQSGSVIRIAHVELADAGQYRCAATNAAGTTQSHVLLLVQALPQISTPPEVRVPAGSAAVFPCMASGYPTPAITWSKVDGDLPPDSRLENNMLMLPSVRPEDAGTYVCTATNRQGKVKAFAYLQVPERVVPYFTQTPYSFLPLPTIKDAYRKFEIKITFRPDSADGMLLYNGQKHTPGSPTNLANRQPDFISFGLVGGRPEFRFDAGSGMATIRHPTPLALGQFHTVTLLRSLTQGSMIVGNLAPVNGTSQGKFQGLDLNEELYLGGYPDYRAIPKAGLSSGFVGCVRELRIQGEEIVFHDVNLTTHGISHCPTCQDRPCQNGGQCHDSESSSYTCVCPAGFTGSRCEHSQALHCHPEACGPDATCVNRPDGRGYNCRCHLGRSGMRCEEGVTVTTPSMSGAGSYLVLPALTNTHHELRLDVEFKPLEPDGILLFSGGKSGPVEDFVSLAMVGGHLEFRYELGSGLAVLRSLEPLALGRWHRVSAERLNKDGSLQVDGGRPVLRSSPGKSQGLNLHTLLYLGGVEPSVQLSPATNMSAHFRGCVGEVSVNGKRLDLTYSFLGSRGVGQCYDSSPCERQPCRNGATCMPAGEYEFQCLCQDGFKGDLCEHEENPCQLQEPCLNGGTCRGTRCLCLPGFSGPRCQQGAGYGVVESDWHPEGSGGNDAPGQYGAYFHDNGFLALPGNSFSRSLPEVPETIEFEVRTSTANGLLLWQGVVKESSRSKDFISLGLQDGHLVFNYQLGSGEARLVSEDPINDGEWHRVTALREGQRGSIQVDGEELVIGRSPGPNVAVNTKDIIYIGGAPDVATLTRGKFSSGITGCLKNLVLHSARPGAPPPQPLDLQHRAQAGANTRPCPS", "length": 4387 }, "evidence": [ { "id": "HGNC:5273", "url": "https://alliancegenome.org/gene/HGNC:5273#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080807-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080807-4#orthology", "database": "AGR" }, { "id": "MGI:96257", "url": "https://alliancegenome.org/gene/MGI:96257#orthology", "database": "AGR" }, { "id": "RGD:621770", "url": "https://alliancegenome.org/gene/RGD:621770#orthology", "database": "AGR" }, { "id": "FB:FBgn0284408", "url": "https://alliancegenome.org/gene/FB:FBgn0284408#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M9PWV8-1", "protein_name": "Basement membrane-specific heparan sulfate proteoglycan core protein isoform X1", "gene_name": "hspg2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGARIRAHKFTLFILPLVFTSHLFNVALSSKVWDEVPFPEDLEEENEQLGDYVDDEGYDPSGDISGEEDGSTPEPSSTDPGPTVTIYYRALVNFTNSFQYVPELDDIYSNAFNEISSAVVDTLESDYNRIPGQQTVNVVLIKKIGKDVFVELDVGSDNNSNETQIREVLFSVVKEGTIASYDTSVVGFQFRRLGEADTLPPVESIFISVKPSPRECTSNEFSCQDGLACIPREYVCDKRPDCNDLSDEIDCGVGVAPLRPTQPTPPRPRPPPGPGPCRADQATCQNGQCISREYLCDGESDCTDGSDESRCGTPSPCEPNEFKCQNGRCALKLWRCDGDNDCQDNSDEMNCPTKRPGAACAPEQFVCLSDRKCIPASYQCDEEPDCADRSDEFGCAPPTVTVSPEESITASRGDTVTFTCSAIGVPVPIITWRLNWGHIPANNRITMISENGQGTLTIRDVKEGDQGAYTCEAINAKGLVFAIPDGVLSLSQKPNPVVSSSPFILAGNCRDGHFSVGGHCMPCFCFGITKKCQSTGRYRNQITLRFTEEEDFKGVNVSFPSRPGLPQPLSSTQMLINPETEEFQLVDLSRRFLDQDSFWSLPRQFLGNKVDSYGGYLKFKVSYSLQRGGSEPKVRPDVVLTGSGQKFIYRRGEPTFPDTFNSREIRFTEENWEHSNGRAVTRDDLMMTLANLESIHIRTIYDNRMASVGLSDISMDTTTKEFSQHGNPREVEECRCPAGYSGLSCESCSPGFERVPGPYLGICAGCNCNGHASACDPVSGHCLSCQHKTEGAQCEKCKPGFFGDPSRGQYDDCKPCPCPYTETSRRFSDTCFLDHDNQATCDACREGYTGRRCEKCAPGYVGNPLQPNGKCIPAASPISKCDNRGTINPISKPCYCKSNVAGALCDECKTGAFHLTADNPEGCLQCFCMGVTKQCASSTWSRDQVRGGVNGQLFTLSNAANTRTISEGITQRGSTEVVYRSFTNIHNDIFYWVLPQNFRGDKVTAYGGELKYRVRYEPHARSMVIDGQPDVVLQGSGIFLEHYSQIKPLPRVPATITVTFRESAWRRADGQPCTREHLLMALADINVFMIRATYADNMAETSLSNIQMDIAVPHSTGNERAMEVEECACPQGYSGPSCQDCDVGYTRTPGLYLGTCEKCECHGHASSCDSETGDCLNCLHNTIGRRCENCISGYYGNPKTGDPQACRPCPCLGQTSNQPSSCYLGSDGQPVCECPAGYTGRRCERCAPGYIGNPQLGQRCTPGSNNGDCYRCDQSGSEGCSGTGVCRCKMNVEGPTCSSCKQGTFHLSPANKDGCLSCFCMGVTQQCTSSRHYRDVVSTMFSPGNYQGFALVNRQRTNRIDNGFSVELSTEGTQLSYTNFNYLGQEPHYWQLPKAYQGDKKASSARTRRANQYPADEARKLDDEIWEIITNFSNGQSSFPFSSSSQSSHSSSFEAQNSLSLSSVRDPSFHSGLTSPLKASESHSSDPAHSSHPDSTQQVEQEKNIIGVVRGPRPVPSNKYVLVYNGFSLHPDDVLFWQLPEPFKGEKVGAYGGKLKYTISYVPGPRGSPIEDADVQIIGNDITLVARQIWQRGHGARESQDFEIVFREEHWQRPDGMPATREHLMMVLADLDDILIRASYHTEMRSSSISGVHMDVAVPEYTSLAQALEVEQCQCPPGYSGLSCQDCASGYTRTGGGLYLGHCEPCECNGHSDTCHPETGICTNCQHNTKGELCEQCVDGFFGDPTAGTPEDCQPCACPGTDPENQFSRTCESLGNGGYQCTACQPGYLGQYCERCAPGYVGNPQARVPCRSDAAFLVVKVYPERVQVAQGLPVTLRCQVSGSPPHYFQWSREDGRPISSSAERRRQGEELHFPGIQSNDAGVYICTCRDQRSSNRSKAEIVVATLPSKPIEVFIEEPKAQSVRVGSTVSFICTAKSKLPAYTLVWTRKGNGKLPNRAMDFNGILTIQNVQPEDAGIYVCTGSNMLGMDEGSAVLYVPEASQSQMFYTAYEMFEGHRKPAEGVQPVATLSPPVQTVKEGDVAQFRCTVTGNPTPAVEWIGGSGKRISSKAVIRNGQLTISSVDRSDEGEYICKALNTHGEHTARGVLHVQSTGQPNGLPHVQVSPQRVEIYEGETLRLYCRAIGSPTPSLKWNKRGGSLPPQAIPSHGFHQFKSNSLDVLQRRIEELQARMDRTDIGTLVVPNIRLSDAGTYLCVGTNAAGSSEAHIDVSVTKGENILSGVIIQPPSASVIEGEALDLNCLVPGTSTGSVKWSRAGGLLSSNHQVLETRLRILRASADDTGDYICTVENGPSPQKATVSVSVTSSASLGLQTPIISIEPHSAVVKQGESASFRCKVHNGAQPVRLEWKLTNNLPLPDNVKVGPDSSIMTVTNAQAKNQGTYRCVASNLYGMTHSIVSLIVRESPKAVVTPAGPVRVRVGDPINLECQAAGEPRPSVRWHRLDNNRKTMLSSTVPVDSSAIIQVLVARPEDSGTYVCSAQNNQGTTETRVEVFVEGGPQVPTVPRASVREPMIIVVEGSTATLHCDAHGFPKPTITWFKERSSLPWRHKIVDNSLILPNVGRQDSGQYVCNATNHLGTSEVTIMLEVDTPPYATSLPNDVSVRVGEVIRLQCLAHGTPPLRYEWTKINGSLPSTAQLQGGDLQINLAKENDAGTYRCVASNKVGKSEALAKVSVRSSLSVKVSPQVEVKALGSAVEFTCAAKGGLQIEWLKEGGVLPPNHHIKDGILRIENLEQSNEGIYTCRVTSQFEHAQDSAKLLIQALPKVKINVRTSVQTVMVGNSVEFECHAIGDPEPTVRWSKVGAPLPDHVEIRGNILRIDQVFESDSGQYRCTATNDVGSEHSHVVLNIQSLPQIAALPESKEVTIGSDAVLPCIASGYPVPTITWSKVENDLPPKCRQDGHALTVPVVTESDAGTYVCTAANKQGKVEAFTRLNVHERVMPYFTQEPLSYLTLPTIKNSYKAFSIKITFRPDNVDGLILYAGMIIYNGQKKTTGADFISFGLLGGRPEFRFDVGSGMATIRYPTPIKLGEFHTVHLYRNQTQGSLVVDGQAPVNGTSQGKFKGLDLNEELFVGGYPNYSMLAKTAGLKTGFVGCIKQLIIQGDEVIFKDLDKSSTGVSNCPTCKDRPCQNDGTCEDSVASLYKCTCKRGFTGSNCQHHSSLHCHTEACGPDATCINRPSGLGYDCRCHLGKSGNKCMDGTLITTPLFDGEDSYIAYPPLTNIHNDLRIEMEFKPMDPDGLMFFSGGKKMKVEDFVAVSMVNGHVEFRYELGTGQAVLRSQEPVSLDQWHRVVAERLNKDGSLTVDHAKEITRSSPGKAQGLNIHTPMYLGGVPSMDILPKPANVSMLFDGCIGEVFINGKKVDLSYSFTESRAISQCNDDSPCDRRPCLHAGTCMATAEYEYQCFCAEGYEGDRCEIVKESCRHSSQCQNGGSCVNNHCVCPAGYSGRHCEKGQESSFSEAMWSLEGSGGNDSPIEYSAYFHDNGYLALPKPMFPRSAPDSPETIELEINTASKDGLILWQGVESAGALNLHKKHANIKELGDQGKGKDFISLGLQNGHLVFSYQLGSGEAQIVSGEPVNDRQWHKITAVRTGKHGYLQIDGGSVQRGQSQGKSIMVNTKGNIYLGGAPDMQALTGGKYSSGMTGCVKNLSLMNARPGEQPARPIDLQVHAEEGINVERCLT", "length": 3701 }, "evidence": [ { "id": "HGNC:5273", "url": "https://alliancegenome.org/gene/HGNC:5273#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080807-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080807-4#orthology", "database": "AGR" }, { "id": "MGI:96257", "url": "https://alliancegenome.org/gene/MGI:96257#orthology", "database": "AGR" }, { "id": "RGD:621770", "url": "https://alliancegenome.org/gene/RGD:621770#orthology", "database": "AGR" }, { "id": "FB:FBgn0284408", "url": "https://alliancegenome.org/gene/FB:FBgn0284408#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P98160-1", "protein_name": "Basement membrane-specific heparan sulfate proteoglycan core protein", "gene_name": "HSPG2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGWRAAGALLLALLLHGRLLAVTHGLRAYDGLSLPEDIETVTASQMRWTHSYLSDDEDMLADSISGDDLGSGDLGSGDFQMVYFRALVNFTRSIEYSPQLEDAGSREFREVSEAVVDTLESEYLKIPGDQVVSVVFIKELDGWVFVELDVGSEGNADGAQIQEMLLRVISSGSVASYVTSPQGFQFRRLGTVPQFPRACTEAEFACHSYNECVALEYRCDRRPDCRDMSDELNCEEPVLGISPTFSLLVETTSLPPRPETTIMRQPPVTHAPQPLLPGSVRPLPCGPQEAACRNGHCIPRDYLCDGQEDCEDGSDELDCGPPPPCEPNEFPCGNGHCALKLWRCDGDFDCEDRTDEANCPTKRPEEVCGPTQFRCVSTNMCIPASFHCDEESDCPDRSDEFGCMPPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTLIIRDVKESDQGAYTCEAMNARGMVFGIPDGVLELVPQRGPCPDGHFYLEHSAACLPCFCFGITSVCQSTRRFRDQIRLRFDQPDDFKGVNVTMPAQPGTPPLSSTQLQIDPSLHEFQLVDLSRRFLVHDSFWALPEQFLGNKVDSYGGSLRYNVRYELARGMLEPVQRPDVVLMGAGYRLLSRGHTPTQPGALNQRQVQFSEEHWVHESGRPVQRAELLQVLQSLEAVLIQTVYNTKMASVGLSDIAMDTTVTHATSHGRAHSVEECRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCNCNGHASSCDPVYGHCLNCQHNTEGPQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPGYTGRRCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGSMGTSGEACRCKNNVVGRLCNECADGSFHLSTRNPDGCLKCFCMGVSRHCTSSSWSRAQLHGASEEPGHFSLTNAASTHTTNEGIFSPTPGELGFSSFHRLLSGPYFWSLPSRFLGDKVTSYGGELRFTVTQRSQPGSTPLHGQPLVVLQGNNIILEHHVAQEPSPGQPSTFIVPFREQAWQRPDGQPATREHLLMALAGIDTLLIRASYAQQPAESRVSGISMDVAVPEETGQDPALEVEQCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSEACEPETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDAAGQCQCKAQVEGLTCSHCRPHHFHLSASNPDGCLPCFCMGITQQCASSAYTRHLISTHFAPGDFQGFALVNPQRNSRLTGEFTVEPVPEGAQLSFGNFAQLGHESFYWQLPETYQGDKVAAYGGKLRYTLSYTAGPQGSPLSDPDVQITGNNIMLVASQPALQGPERRSYEIMFREEFWRRPDGQPATREHLLMALADLDELLIRATFSSVPLAASISAVSLEVAQPGPSNRPRALEVEECRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDLCHPETGACSQCQHNAAGEFCELCAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGYTGQYCEQCGPGYVGNPSVQGGQCLPETNQAPLVVEVHPARSIVPQGGSHSLRCQVSGSPPHYFYWSREDGRPVPSGTQQRHQGSELHFPSVQPSDAGVYICTCRNLHQSNTSRAELLVTEAPSKPITVTVEEQRSQSVRPGADVTFICTAKSKSPAYTLVWTRLHNGKLPTRAMDFNGILTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEWTGGPGGQLPAKAQIHGGILRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHVHGGGGPRVQVSPERTQVHAGRTVRLYCRAAGVPSATITWRKEGGSLPPQARSERTDIATLLIPAITTADAGFYLCVATSPAGTAQARIQVVVLSASDASPPPVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRRGGSLPPHTQVHGSRLRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGGSLPARHQTHGSLLRLHQVTPADSGEYVCHVVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPARHQVRGSRLYIFQASPADAGQYVCRASNGMEASITVTVTGTQGANLAYPAGSTQPIRIEPSSSQVAEGQTLDLNCVVPGQSHAQVTWHKRGGSLPVRHQTHGSLLRLYQASPADSGEYVCRVLGSSVPLEASVLVTIEPAGSVPALGVTPTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGGSLPARHQVHGSRLRLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDLNCLVASQAPHTITWYKRGGSLPSRHQIVGSRLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSPPIRIESSSPTVVEGQTLDLNCVVARQPQAIITWYKRGGSLPSRHQTHGSHLRLHQMSVADSGEYVCRANNNIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVTWHKRGGSLPSHHQTRGSRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQAHAQVTWHKRGGNLPARHQVHGPLLRLNQVSPADSGEYSCQVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKRGGSLPARHQTHGSQLRLHLVSPADSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELEDNVHISPNGSIITIVGTRPSNHGTYRCVASNAYGVAQSVVNLSVHGPPTVSVLPEGPVWVKVGKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCLAQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGSPAPTIHWSKLRSPLPWQHRLEGDTLIIPRVAQQDSGQYICNATSPAGHAEATIILHVESPPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSSLPGRATARNELLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVEFHCAVPSDRGTQLRWFKEGGQLPPGHSVQDGVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQALPSVLINIRTSVQTVVVGHAVEFECLALGDPKPQVTWSKVGGHLRPGIVQSGGVVRIAHVELADAGQYRCTATNAAGTTQSHVLLLVQALPQISMPQEVRVPAGSAAVFPCIASGYPTPDISWSKLDGSLPPDSRLENNMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQVPERVVPYFTQTPYSFLPLPTIKDAYRKFEIKITFRPDSADGMLLYNGQKRVPGSPTNLANRQPDFISFGLVGGRPEFRFDAGSGMATIRHPTPLALGHFHTVTLLRSLTQGSLIVGDLAPVNGTSQGKFQGLDLNEELYLGGYPDYGAIPKAGLSSGFIGCVRELRIQGEEIVFHDLNLTAHGISHCPTCRDRPCQNGGQCHDSESSSYVCVCPAGFTGSRCEHSQALHCHPEACGPDATCVNRPDGRGYTCRCHLGRSGLRCEEGVTVTTPSLSGAGSYLALPALTNTHHELRLDVEFKPLAPDGVLLFSGGKSGPVEDFVSLAMVGGHLEFRYELGSGLAVLRSAEPLALGRWHRVSAERLNKDGSLRVNGGRPVLRSSPGKSQGLNLHTLLYLGGVEPSVPLSPATNMSAHFRGCVGEVSVNGKRLDLTYSFLGSQGIGQCYDSSPCERQPCQHGATCMPAGEYEFQCLCRDGFKGDLCEHEENPCQLREPCLHGGTCQGTRCLCLPGFSGPRCQQGSGHGIAESDWHLEGSGGNDAPGQYGAYFHDDGFLAFPGHVFSRSLPEVPETIELEVRTSTASGLLLWQGVEVGEAGQGKDFISLGLQDGHLVFRYQLGSGEARLVSEDPINDGEWHRVTALREGRRGSIQVDGEELVSGRSPGPNVAVNAKGSVYIGGAPDVATLTGGRFSSGITGCVKNLVLHSARPGAPPPQPLDLQHRAQAGANTRPCPS", "length": 4391 }, "evidence": [ { "id": "HGNC:5273", "url": "https://alliancegenome.org/gene/HGNC:5273#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080807-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080807-4#orthology", "database": "AGR" }, { "id": "MGI:96257", "url": "https://alliancegenome.org/gene/MGI:96257#orthology", "database": "AGR" }, { "id": "RGD:621770", "url": "https://alliancegenome.org/gene/RGD:621770#orthology", "database": "AGR" }, { "id": "FB:FBgn0284408", "url": "https://alliancegenome.org/gene/FB:FBgn0284408#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q05793-1", "protein_name": "Basement membrane-specific heparan sulfate proteoglycan core protein", "gene_name": "Hspg2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQRAVGSLLLGLLLHARLLAVTHGLRAYDGLSLPEDTETVTASRYGWTYSYLSDDEDLLADDASGDGLGSGDVGSGDFQMVYFRALVNFTRSIEYSPQLEDASAKEFREVSEAVVEKLEPEYRKIPGDQIVSVVFIKELDGWVFVELDVGSEGNADGSQIQEVLHTVVSSGSIGPYVTSPWGFKFRRLGTVPQFPRVCTETEFACHSYNECVALEYRCDRRPDCRDMSDELNCEEPVPELSSSTPAVGKVSPLPLWPEAATTPPPPVTHGPQFLLPSVPGPSACGPQEASCHSGHCIPRDYLCDGQEDCRDGSDELGCASPPPCEPNEFACENGHCALKLWRCDGDFDCEDRTDEANCSVKQPGEVCGPTHFQCVSTNRCIPASFHCDEESDCPDRSDEFGCMPPQVVTPPQQSIQASRGQTVTFTCVATGVPTPIINWRLNWGHIPAHPRVTMTSEGGRGTLIIRDVKEADQGAYTCEAMNSRGMVFGIPDGVLELVPQRGPCPDGHFYLEDSASCLPCFCFGVTNVCQSSLRFRDQIRLSFDQPNDFKGVNVTMPSQPGVPPLSSTQLQIDPALQEFQLVDLSRRFLVHDAFWALPKQFLGNKVDSYGGFLRYKVRYELARGMLEPVQKPDVILVGAGYRLHSRGHTPTHPGTLNQRQVQLSEEHWVHESGRPVQRAEMLQALASLEAVLLQTVYNTKMASVGLSDIVMDTTVTHTTIHGRAHSVEECRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCNCNGHASSCDPVYGHCLNCQHNTEGPQCDKCKPGFFGDATKATATACRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPGYTGRRCESCAPGYEGNPIQPGGKCRPTTQEIVRCDERGSLGTSGETCRCKNNVVGRLCNECSDGSFHLSKQNPDGCLKCFCMGVSRQCSSSSWSRAQVLGASEQPSQFSLSNAAGTHTTSEGVSSPAPGELSFSSFHNLLSEPYFWSLPASFRGDKVTSYGGELRFTVMQRPRPSSAPLHRQPLVVLQGNNIVLEHHASRDPSPGQPSNFIVPFQEQAWQRPDGQPATREHLLMALAGIDALLIQASYTQQPAESRLSGISMDVAVPENTGQDSAREVEQCTCPPGYRGPSCQDCDTGYTRVPSGLYLGTCERCNCHGHSETCEPETGACQSCQHHTEGASCEQCQPGYYGDAQRGTPQDCQPCPCYGAPAAGQAAHTCFLDTDGHPTCDSCSPGHSGRHCERCAPGYYGNPSQGQPCHRDGQVPEVLGCGCDPHGSISSQCDAAGQCQCKAQVEGRSCSHCRPHHFHLSASNPEGCLPCFCMGVTQQCASSSYSRQLISTHFAPGDFQGFALVNPQRNSQLTGGFTVEPVHDGARLSFSNFAHLGQESFYWQLPEIYQGDKVAAYGGKLRYTLSYTAGPQGSPLLDPDIQITGNNIMLVASQPALQGPERRSYEIIFREEFWRRPDGQPATREHLLMALADLDELLVRATFSSVPRAASISAVSLEGAQPGPSSGPRALEVEECRCPPGYVGLSCQDCAPGYTRTGSGLYLGQCELCECNGHSDLCHPETGACSRCQHNTAGEFCELCATGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGYTGQYCEQCAPGYEGDPNVQGGRCQPLTKESLEVQIHPSRSVVPQGGPHSLRCQVSGSPPHYFYWSREDGRPLPSSAQQRHQGSELHFPSVQPSDAGVYICTCRNLIHTSNSRAELLVAEAPSKPIMVTVEEQRSQSVRPGADVTFICTAKSKSPAYTLVWTRLHNGKLPSRAMDFNGILTIRNVQPSDAGTYVCTGSNMFAMDQGTATLHVQVSGTSTAPVASIHPPQLTVQPGQQAEFRCSATGNPTPMLEWIGGPSGQLPAKAQIHNGILRLPAIEPSDQGQYLCRALSSAGQHVARAMLQVHGGSGPRVQVSPERTQVHEGRTVRLYCRAAGVPSASITWRKEGGSLPFRHQAHGSRLRLHHMSVADSGEYVCRANNNIDAQETSIMISVSPSTNSPPAPASPAPIRIESSSSRVAEGQTLDLNCVVPGHAHAQVTWHKRGGSLPTHHQTHGSRLRLYQVSSADSGEYVCSVLSSSGPLEASVLVSITPAAANVHIPGVVPPIRIETSSSRVAEGQTLDLSCVVPGQAHAQVTWHKRGGSLPAGHQVHGHMLRLNRVSPADSGEYSCQVTGSSGTLEASVLVTIEASEPSPIPAPGLAQPVYIESSSSHLTEGQTVDLKCVVPGQAHAQVTWHKRGSSLPARHQTHGSLLRLYQLSPADSGEYVCQVAGSSHPEHEASFKLTVPSSQNSSFRLRSPVISIEPPSSTVQQGQDASFKCLIHEGAMPIKVEWKIRDQELEDNVHISPNGSIITIVAPGPATMEPTACVASNVYGMAQSVVNLSVHGPPTVSVLPEGPVHVKMGKDITLECISSGEPRSSPRWTRLGIPVKLEPRMFGLMNSHAMLKIASVKPSDAGTYVCQAQNALGTAQKQVELIVDTGTVAPGTPQVQVEESELTLEAGHTATLHCSATGNPPPTIHWSKLRAPLPWQHRIEGNTLVIPRVAQQDSGQYICNATNSAGHTEATVVLHVESPPYATIIPEHTSAQPGNLVQLQCLAHGTPPLTYQWSLVGGVLPEKAVVRNQLLRLEPTVPEDSGRYRCQVSNRVGSAEAFAQVLVQGSSSNLPDTSIPGGSTPTVQVTPQLETRNIGASVEFHCAVPNERGTHLRWLKEGGQLPPGHSVQDGVLRIQNLDQNCQGTYVCQAHGPWGQAQATAQLIVQALPSVLINVRTSVHSVVVGHSVEFECLALGDPKPQVTWSKVGGHLRPGIVQSGTIIRIAHVELADAGQYRCAATNAAGTTQSHVLLLVQALPQISTPPEIRVPAGSAAVFPCMASGYPTPAITWSKVDGDLPPDSRLENNMLMLPSVRPEDAGTYVCTATNRQGKVKAFAYLQVPERVIPYFTQTPYSFLPLPTIKDAYRKFEIKITFRPDSADGMLLYNGQKRSPTNLANRQPDFISFGLVGGRPEFRFDAGSGMATIRHPTPLALGQFHTVTLLRSLTQGSLIVGNLAPVNGTSQGKFQGLDLNEELYLGGYPDYGAIPKAGLSSGFVGCVRELRIQGEEIVFHDVNLTTHGISHCPTCQDRPCQNGGQCQDSESSSYTCVCPAGFTAAAVNIRKPCTATPSLWADATCVNRPDGRGYTCRCHLGRSGVRCEEGVTVTTPSMSGAGSYLALPALTNTHHELRLDVEFKPLEPNGILLFSGGKSGPVEDFVSLAMVGGHLEFRYELGSGLAVLRSHEPLALGRWHRVSAERLNKDGSLRVDGGRPVLRSSPGKSQGLNLHTLLYLGGVEPSVQLSPATNMSAHFHGCVGEVSVNGKRLDLTYSFLGSQGVGQCYDSSPCERQPCRNGATCMPAGEYEFQCLCQDGFKGDLCEHEENPCQLHEPCLNGGTCRGARCLCLPGFSGPRCQQGAGYGVVESDWHPEGSGGNDAPGQYGAYFYDNGFLGLPGNSFSRSLPEVPETIEFEVRTSTADGLLLWQGVVREASRSKDFISLGLQDGHLVFSYQLGSGEARLVSGDPINDGEWHRITALREGQRGSIQVDGEDLVTGRSPGPNVAVNTKDIIYIGGAPDVATLTRGKFSSGITGCIKNLVLHTARPGAPPPQPLDLQHRAQAGANTRPCPS", "length": 3707 }, "evidence": [ { "id": "HGNC:5273", "url": "https://alliancegenome.org/gene/HGNC:5273#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080807-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080807-4#orthology", "database": "AGR" }, { "id": "MGI:96257", "url": "https://alliancegenome.org/gene/MGI:96257#orthology", "database": "AGR" }, { "id": "RGD:621770", "url": "https://alliancegenome.org/gene/RGD:621770#orthology", "database": "AGR" }, { "id": "FB:FBgn0284408", "url": "https://alliancegenome.org/gene/FB:FBgn0284408#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAU3", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3" } ], "pmid": "" }, { "name": "basement membrane", "id": "GO:0005604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005604", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAU3", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAU3", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAU3", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAU3", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 21, "go_terms": [ { "name": "epithelial cell differentiation", "id": "GO:0030855", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030855", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAU3", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3" } ], "pmid": "" }, { "name": "regulation of growth", "id": "GO:0040008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040008", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAU3", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAU3", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3" } ], "pmid": "" }, { "name": "positive regulation of neurogenesis", "id": "GO:0050769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050769", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAU3", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3" } ], "pmid": "" }, { "name": "regionalization", "id": "GO:0003002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003002", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAU3", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3" } ], "pmid": "" }, { "name": "regulation of plasma membrane bounded cell projection organization", "id": "GO:0120035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120035", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAU3", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3" } ], "pmid": "" }, { "name": "open tracheal system development", "id": "GO:0007424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007424", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAU3", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3" } ], "pmid": "" }, { "name": "imaginal disc-derived wing morphogenesis", "id": "GO:0007476", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007476", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAU3", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3" } ], "pmid": "" }, { "name": "ommatidial rotation", "id": "GO:0016318", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016318", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAU3", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3" } ], "pmid": "" }, { "name": "R3/R4 cell differentiation", "id": "GO:0048056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048056", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAU3", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAU3", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3" } ], "pmid": "" }, { "name": "maintenance of epithelial cell apical/basal polarity", "id": "GO:0045199", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045199", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAU3", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3" } ], "pmid": "" }, { "name": "motor neuron axon guidance", "id": "GO:0008045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008045", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAU3", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3" } ], "pmid": "" }, { "name": "response to anesthetic", "id": "GO:0072347", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072347", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAU3", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3" } ], "pmid": "" }, { "name": "positive regulation of semaphorin-plexin signaling pathway", "id": "GO:2001262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001262", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAU3", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3" } ], "pmid": "" }, { "name": "defasciculation of motor neuron axon", "id": "GO:0007415", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007415", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAU3", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3" } ], "pmid": "" }, { "name": "animal organ development", "id": "GO:0048513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048513", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAU3", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3" } ], "pmid": "" }, { "name": "positive regulation of smoothened signaling pathway", "id": "GO:0045880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045880", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAU3", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3" } ], "pmid": "" }, { "name": "positive regulation of neuroblast proliferation", "id": "GO:0002052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002052", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAU3", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAU3" } ], "pmid": "" }, { "name": "negative regulation of fibroblast growth factor receptor 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"categories": [ "Protein" ] }, { "id": "A0ACD4DAI6-1", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAI6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A1Z8Y9", "url": "https://www.uniprot.org/uniprotkb/A1Z8Y9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A1Z8Y9-1", "url": "https://www.uniprot.org/uniprotkb/A1Z8Y9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A1Z8Z0", "url": "https://www.uniprot.org/uniprotkb/A1Z8Z0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A1Z8Z0-1", "url": "https://www.uniprot.org/uniprotkb/A1Z8Z0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSKIKKIHVLLLLYLTVQIAKTNELKEANIKVYCSEYVPYGIRTNIVIAMESIPVKYKVTILLSTPSYLLSFFELGNVANGMGPSFRSTSSISEELSIYGIKSKTKPEYEQGYFADLSATFWSVSDKVLTLLGRIKLNRIYEIKVSIPIEVSLPPRCAPQLTVPKCSDPLSPRKVLITRGISINALFLESSQFASYTTDGPFINIPAFTMRFPTSHEAWRDLYLLQVEGSVNGVQFAARCYLKSIMGNVEAVILGGQNRLARQSETIWMNGSMSYDLSKRRGDIQFSIYNWNCYSVNDIDNPFCHRNISSVSVFSIPAKSFKSGCRYTFRLQVFRDGNPNVSSQKMQAITVIEHKILEVTIECLRNCKNDFFTPSSKIHLRSNCINCGGQLVRYKWFVDGQLLVTSRDLALYIRSAPKEIRIKLIVYSKYGIYGRKVKTLFKNTGPRGGICSVYPRQGYEGITPFYPCCQNFGSLNGHKEYWYYAGSVLVGSCVDCNCEVYLPITSSIKVLVCDVTWACRTTWIEVKIIPLRSIPKNIHGLLEKGHMQRYLQIMQSAASHLTKAQSGLYLTRNLTNIPFQSRSSLARLANLTLTLAHRLYFVDQQKESLLTKMVKIINNNFERIKRNEEETFLMEKPFDNLRLACREVYEIIKRLCKDTPSPPMSVYDQYYRAFSTGKLDQSFVEKLVDETQKLAKDKSTSSWVMWLNSTWEMERLYRHLNYDRGLYRSDIIDPRKEMSNGVALEVQCFDTFPKKIVRVLSSDRIHMVLFARAVLNEVLKTDEGRVCLKLVSMKLKLNWWYPINKKPSTLVLSVRIYQREDNFTVQIPLNRSQIHMKTFITYDPEFDTEIRNSLISSTRSPRAISFSSTEVKNCLTEGTLQTHQEIRMYRMVLMEHTLLAVQFTTSTHKLQVVLRTKEKPSVREISNSKCTIPALTTNATILLRNNCHKADRAYIALRLYRDTSMGKADNSPIANGPARFAFVFQIRSCDTWQYSASLDNQKWLHYGCYPTMDLSVEKGIRCTCNVLGTYTDYLYYIPGVEVPIGVFQAAKLNILIILVYLTALLIILLWILWLYRYRSKLPSKTIRFPKFELDDESTGELHDVLISLRTGGRINAGTTASVHLSFRGQSQPVRHIEIMQDPENIFLKSNTTLYIWVRTRDIRIPTKVMVYHNNAGRFPMWFLRRIEVTDIQTGETQVFLARKWLEKGTLLMSSTLIYKQGDVRMFDVWKNRFMMSFEMFWINWSLWQPVTGSWRESAHYPRMSRAKRFCEFICKLLVNYTICASFFGVTTSENLHLMRSLFLNYKDIIVLTMICSFVNVMLQTMFNLVNYKFG", "length": 1334, "header": "tr|A0ACD4DAI6-1|A0ACD4DAI6_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=CG30048 PE=3 SV=1 CANONICAL=A0ACD4DAI6-1" }, "isoforms": [ { "isoform_ac": "A0ACD4DAI6-1", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAI6/entry#A0ACD4DAI6-1", "sequence": { "sequence": "MSKIKKIHVLLLLYLTVQIAKTNELKEANIKVYCSEYVPYGIRTNIVIAMESIPVKYKVTILLSTPSYLLSFFELGNVANGMGPSFRSTSSISEELSIYGIKSKTKPEYEQGYFADLSATFWSVSDKVLTLLGRIKLNRIYEIKVSIPIEVSLPPRCAPQLTVPKCSDPLSPRKVLITRGISINALFLESSQFASYTTDGPFINIPAFTMRFPTSHEAWRDLYLLQVEGSVNGVQFAARCYLKSIMGNVEAVILGGQNRLARQSETIWMNGSMSYDLSKRRGDIQFSIYNWNCYSVNDIDNPFCHRNISSVSVFSIPAKSFKSGCRYTFRLQVFRDGNPNVSSQKMQAITVIEHKILEVTIECLRNCKNDFFTPSSKIHLRSNCINCGGQLVRYKWFVDGQLLVTSRDLALYIRSAPKEIRIKLIVYSKYGIYGRKVKTLFKNTGPRGGICSVYPRQGYEGITPFYPCCQNFGSLNGHKEYWYYAGSVLVGSCVDCNCEVYLPITSSIKVLVCDVTWACRTTWIEVKIIPLRSIPKNIHGLLEKGHMQRYLQIMQSAASHLTKAQSGLYLTRNLTNIPFQSRSSLARLANLTLTLAHRLYFVDQQKESLLTKMVKIINNNFERIKRNEEETFLMEKPFDNLRLACREVYEIIKRLCKDTPSPPMSVYDQYYRAFSTGKLDQSFVEKLVDETQKLAKDKSTSSWVMWLNSTWEMERLYRHLNYDRGLYRSDIIDPRKEMSNGVALEVQCFDTFPKKIVRVLSSDRIHMVLFARAVLNEVLKTDEGRVCLKLVSMKLKLNWWYPINKKPSTLVLSVRIYQREDNFTVQIPLNRSQIHMKTFITYDPEFDTEIRNSLISSTRSPRAISFSSTEVKNCLTEGTLQTHQEIRMYRMVLMEHTLLAVQFTTSTHKLQVVLRTKEKPSVREISNSKCTIPALTTNATILLRNNCHKADRAYIALRLYRDTSMGKADNSPIANGPARFAFVFQIRSCDTWQYSASLDNQKWLHYGCYPTMDLSVEKGIRCTCNVLGTYTDYLYYIPGVEVPIGVFQAAKLNILIILVYLTALLIILLWILWLYRYRSKLPSKTIRFPKFELDDESTGELHDVLISLRTGGRINAGTTASVHLSFRGQSQPVRHIEIMQDPENIFLKSNTTLYIWVRTRDIRIPTKVMVYHNNAGRFPMWFLRRIEVTDIQTGETQVFLARKWLEKGTLLMSSTLIYKQGDVRMFDVWKNRFMMSFEMFWINWSLWQPVTGSWRESAHYPRMSRAKRFCEFICKLLVNYTICASFFGVTTSENLHLMRSLFLNYKDIIVLTMICSFVNVMLQTMFNLVNYKFG", "length": 1334, "header": "tr|A0ACD4DAI6-1|A0ACD4DAI6_DROME Isoform 1 of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=CG30048 PE=3 SV=1 CANONICAL=A0ACD4DAI6-1" }, "locus": {} }, { "isoform_ac": "A1Z8Y9-1", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAI6/entry#A1Z8Y9-1", "sequence": { "sequence": "MQAITVIEHKILEVTIECLRNCKNDFFTPSSKIHLRSNCINCGGQLVRYKWFVDGQLLVTSRDLALYIRSAPKEIRIKLIVYSKYGIYGRKVKTLFKNTGPRGGICSVYPRQGYEGITPFYPCCQNFGSLNGHKEYWYYAGSVLVGSCVDCNCEVYLPITSSIKVLVCDVTWACRTTWIEVKIIPLRSIPKNIHGLLEKGHMQRYLQIMQSAASHLTKAQSGLYLTRNLTNIPFQSRSSLARLANLTLTLAHRLYFVDQQKESLLTKMVKIINNNFERIKRNEEETFLMEKPFDNLRLACREVYEIIKRLCKDTPSPPMSVYDQYYRAFSTGKLDQSFVEKLVDETQKLAKDKSTSSWVMWLNSTWEMERLYRHLNYDRGLYRSDIIDPRKEMSNGVALEVQCFDTFPKKIVRVLSSDRIHMVLFARAVLNEVLKTDEGRVCLKLVSMKLKLNWWYPINKKPSTLVLSVRIYQREDNFTVQIPLNRSQIHMKTFITYDPEFDTEIRNSLISSTRSPRAISFSSTEVKNCLTEGTLQTHQEIRMYRMVLMEHTLLAVQFTTSTHKLQVVLRTKEKPSVREISNSKCTIPALTTNATILLRNNCHKADRAYIALRLYRDTSMGKADNSPIANGPARFAFVFQIRSCDTWQYSASLDNQKWLHYGCYPTMDLSVEKGIRCTCNVLGTYTDYLYYIPGVEVPIGVFQAAKLNILIILVYLTALLIILLWILWLYRYRSKLPSKTIRFPKFELDDESTGELHDVLISLRTGGRINAGTTASVHLSFRGQSQPVRHIEIMQDPENIFLKSNTTLYIWVRTRDIRIPTKVMVYHNNAGRFPMWFLRRIEVTDIQTGETQVFLARKWLEKGTLLMSSTLIYKQGDVRMFDVWKNRFMMSFEMFWINWSLWQPVTGSWRESAHYPRMSRAKRFCEFICKLLVNYTICASFFGVTTSENLHLMRSLFLNYKDIIVLTMICSFVNVMLQTMFNLVNYKFG", "length": 989, "header": "tr|A1Z8Y9-1|A0ACD4DAI6_DROME Computationally mapped isoform of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=CG30048 PE=3 SV=2 CANONICAL=A0ACD4DAI6-1" }, "locus": {} }, { "isoform_ac": "A1Z8Z0-1", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAI6/entry#A1Z8Z0-1", "sequence": { "sequence": "MRFPTSHEAWRDLYLLQVEGSVNGVQFAARCYLKSIMGNVEAVILGGQNRLARQSETIWMNGSMSYDLSKRRGDIQFSIYNWNCYSVNDIDNPFCHRNISSVSVFSIPAKSFKSGCRYTFRLQVFRDGNPNVSSQKMQAITVIEHKILEVTIECLRNCKNDFFTPSSKIHLRSNCINCGGQLVRYKWFVDGQLLVTSRDLALYIRSAPKEIRIKLIVYSKYGIYGRKVKTLFKNTGPRGGICSVYPRQGYEGITPFYPCCQNFGSLNGHKEYWYYAGSVLVGSCVDCNCEVYLPITSSIKVLVCDVTWACRTTWIEVKIIPLRSIPKNIHGLLEKGHMQRYLQIMQSAASHLTKAQSGLYLTRNLTNIPFQSRSSLARLANLTLTLAHRLYFVDQQKESLLTKMVKIINNNFERIKRNEEETFLMEKPFDNLRLACREVYEIIKRLCKDTPSPPMSVYDQYYRAFSTGKLDQSFVEKLVDETQKLAKDKSTSSWVMWLNSTWEMERLYRHLNYDRGLYRSDIIDPRKEMSNGVALEVQCFDTFPKKIVRVLSSDRIHMVLFARAVLNEVLKTDEGRVCLKLVSMKLKLNWWYPINKKPSTLVLSVRIYQREDNFTVQIPLNRSQIHMKTFITYDPEFDTEIRNSLISSTRSPRAISFSSTEVKNCLTEGTLQTHQEIRMYRMVLMEHTLLAVQFTTSTHKLQVVLRTKEKPSVREISNSKCTIPALTTNATILLRNNCHKADRAYIALRLYRDTSMGKADNSPIANGPARFAFVFQIRSCDTWQYSASLDNQKWLHYGCYPTMDLSVEKGIRCTCNVLGTYTDYLYYIPGVEVPIGVFQAAKLNILIILVYLTALLIILLWILWLYRYRSKLPSKTIRFPKFELDDESTGELHDVLISLRTGGRINAGTTASVHLSFRGQSQPVRHIEIMQDPENIFLKSNTTLYIWVRTRDIRIPTKVMVYHNNAGRFPMWFLRRIEVTDIQTGETQVFLARKWLEKGTLLMSSTLIYKQGDVRMFDVWKNRFMMSFEMFWINWSLWQPVTGSWRESAHYPRMSRAKRFCEFICKLLVNYTICASFFGVTTSENLHLMRSLFLNYKDIIVLTMICSFVNVMLQTMFNLVNYKFG", "length": 1125, "header": "tr|A1Z8Z0-1|A0ACD4DAI6_DROME Computationally mapped isoform of Uncharacterized protein OS=Drosophila melanogaster OX=7227 GN=CG30048 PE=3 SV=2 CANONICAL=A0ACD4DAI6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "A1Z8Y9", "url": "https://www.uniprot.org/uniprotkb/A1Z8Y9" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "A1Z8Y9", "url": "https://www.uniprot.org/uniprotkb/A1Z8Y9" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "A1Z8Y9", "url": "https://www.uniprot.org/uniprotkb/A1Z8Y9" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "A1Z8Y9", "url": "https://www.uniprot.org/uniprotkb/A1Z8Y9" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "A1Z8Y9", "url": "https://www.uniprot.org/uniprotkb/A1Z8Y9" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "A1Z8Y9", "url": "https://www.uniprot.org/uniprotkb/A1Z8Y9" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "A1Z8Y9", "url": "https://www.uniprot.org/uniprotkb/A1Z8Y9" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "A1Z8Y9", "url": "https://www.uniprot.org/uniprotkb/A1Z8Y9" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "A1Z8Y9", "url": "https://www.uniprot.org/uniprotkb/A1Z8Y9" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "A1Z8Y9", "url": "https://www.uniprot.org/uniprotkb/A1Z8Y9" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "A1Z8Y9", "url": "https://www.uniprot.org/uniprotkb/A1Z8Y9" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAI6", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAI6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAI6", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAI6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "calcium ion transport", "id": "GO:0006816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006816", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAI6", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAI6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1150, "end_pos": 1152, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1243, "end_pos": 1245, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1279, "end_pos": 1281, "annotation": "n_glycosylation_sequon" }, { "start_pos": 270, "end_pos": 272, "annotation": "n_glycosylation_sequon" }, { "start_pos": 307, "end_pos": 309, "annotation": "n_glycosylation_sequon" }, { "start_pos": 340, "end_pos": 342, "annotation": "n_glycosylation_sequon" }, { "start_pos": 573, "end_pos": 575, "annotation": "n_glycosylation_sequon" }, { "start_pos": 590, "end_pos": 592, "annotation": "n_glycosylation_sequon" }, { "start_pos": 708, "end_pos": 710, "annotation": "n_glycosylation_sequon" }, { "start_pos": 822, "end_pos": 824, "annotation": "n_glycosylation_sequon" }, { "start_pos": 830, "end_pos": 832, "annotation": "n_glycosylation_sequon" }, { "start_pos": 938, "end_pos": 940, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ACD4DAI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAI6" }, { "id": "PS50095", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50095" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PLAT", "eco_id": "ECO_0000259", "start_pos": 1102, "end_pos": 1219, "start_aa": "His", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0ACD4DAI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAI6" }, { "id": "PS51111", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51111" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "REJ", "eco_id": "ECO_0000259", "start_pos": 25, "end_pos": 843, "start_aa": "Leu", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAV1" } ] }, { "name": "Mgn1457", "type": "synonym", "evidence": [ { "id": "NP_001401057", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001401057" }, { "id": "A0ACD4DAV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAV1" } ] }, { "name": "l(1)G0289", "type": "synonym", "evidence": [ { "id": "NP_001401057", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001401057" } ] } ], "protein_names": [ { "name": "CG2221-PD", "type": "synonym", "evidence": [ { "id": "NP_001401057", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001401057" } ] }, { "name": "Lethal (1) G0289, isoform D", "type": "synonym", "evidence": [ { "id": "A0ACD4DAV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAV1/entry#names_and_taxonomy" } ] }, { "name": "l(1)G0289-PD", "type": "synonym", "evidence": [ { "id": "NP_001401057", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001401057" } ] }, { "name": "lethal (1) G0289, isoform D", "type": "synonym", "evidence": [ { "id": "NP_001401057", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001401057" } ] }, { "name": "lethal (1) G0289", "type": "synonym", "evidence": [ { "id": "NP_001401057", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001401057" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAV1", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAV1" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "l(1)G0289", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAV1", "locus": { "chromosome": "X", "start_pos": 10348680, "end_pos": 10366273, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0028331", "url": "https://www.ensemblgenomes.org/id/FBgn0028331" } ] } } ], "crossref": [ { "id": "FB:FBgn0028331", "url": "https://alliancegenome.org/gene/FB:FBgn0028331", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "FBgn0028331", "url": "https://bgee.org/?page=gene&gene_id=FBgn0028331", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0028331", "url": "https://flybase.org/reports/FBgn0028331", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "31964", "url": "https://www.ncbi.nlm.nih.gov/gene/31964", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002165", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002165", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG2221", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG2221", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IDKHLYF", "url": "https://omabrowser.org/oma/group/IDKHLYF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q9W2V9", "url": "https://www.orthodb.org/?gene=Q9W2V9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13055", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13055", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13055:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13055:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01437", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01437", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q9W2V9", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q9W2V9", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001401057", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001401057", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0ACD4DAV1", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ACD4DAV1-1", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAV1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W2V9", "url": "https://www.uniprot.org/uniprotkb/Q9W2V9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W2V9-1", "url": "https://www.uniprot.org/uniprotkb/Q9W2V9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAKSVGSACAQIAILLAITCSASELASAVLHQDTYEIVDTNLPNIAAYGVVPLRTDRLHRQRRTVPVSPPLPAVTTYRGAVSANATAEAGGAAGAGGGVAAETTVTTVDNKAAGGSVSYNVHNVGVNGTGQRKTYDVAPAVDSNTTSQMAPATKKPTLLGQSGNPKKVASSVVAATMTDPSPAVIDVDVSKVVDVPEEEIEAAVKNASLKESVDFHEYYNSVLYENKDEVASLWTELKATPENIMLSSSHRRAMTVELKFDFPFYGHFVRNITVATGGFLYTGEYVHSWLAATQYIAPLMANFDTSMSNDSFVRLHDNGTAFTAVWENVTLQDKPDFGKFTFSVTLYQSGDIVFAYMLVPTNINSIQDKEHPVKVGLSDAYIIDKQLFFARRKTIYEYHRVTFQQHEITNNTIIKLAAQPTCLGYNDCNSCINHNTTFTCLWCSVLNRCSTGTDRKKHEWLQMGCEATAIHTSSLCPALGDKGNNAAGQGKNGSANSGASANGATNTSTSSSGSSTPVTEPSVMSTRAPHATAYIKPGVDHSSDIHADGKVGNAELSKAEADNKNVGVAFGFMVPICLVFAVTLWLFYAYRNPHTKSGQLLIQSKQFRPSQWSWRRGEARYTAATIHM", "length": 628, "header": "tr|A0ACD4DAV1-1|A0ACD4DAV1_DROME Isoform 1 of Lethal (1) G0289, isoform D OS=Drosophila melanogaster OX=7227 GN=l(1)G0289 PE=1 SV=1 CANONICAL=A0ACD4DAV1-1" }, "isoforms": [ { "isoform_ac": "A0ACD4DAV1-1", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAV1/entry#A0ACD4DAV1-1", "sequence": { "sequence": "MAKSVGSACAQIAILLAITCSASELASAVLHQDTYEIVDTNLPNIAAYGVVPLRTDRLHRQRRTVPVSPPLPAVTTYRGAVSANATAEAGGAAGAGGGVAAETTVTTVDNKAAGGSVSYNVHNVGVNGTGQRKTYDVAPAVDSNTTSQMAPATKKPTLLGQSGNPKKVASSVVAATMTDPSPAVIDVDVSKVVDVPEEEIEAAVKNASLKESVDFHEYYNSVLYENKDEVASLWTELKATPENIMLSSSHRRAMTVELKFDFPFYGHFVRNITVATGGFLYTGEYVHSWLAATQYIAPLMANFDTSMSNDSFVRLHDNGTAFTAVWENVTLQDKPDFGKFTFSVTLYQSGDIVFAYMLVPTNINSIQDKEHPVKVGLSDAYIIDKQLFFARRKTIYEYHRVTFQQHEITNNTIIKLAAQPTCLGYNDCNSCINHNTTFTCLWCSVLNRCSTGTDRKKHEWLQMGCEATAIHTSSLCPALGDKGNNAAGQGKNGSANSGASANGATNTSTSSSGSSTPVTEPSVMSTRAPHATAYIKPGVDHSSDIHADGKVGNAELSKAEADNKNVGVAFGFMVPICLVFAVTLWLFYAYRNPHTKSGQLLIQSKQFRPSQWSWRRGEARYTAATIHM", "length": 628, "header": "tr|A0ACD4DAV1-1|A0ACD4DAV1_DROME Isoform 1 of Lethal (1) G0289, isoform D OS=Drosophila melanogaster OX=7227 GN=l(1)G0289 PE=1 SV=1 CANONICAL=A0ACD4DAV1-1" }, "locus": {} }, { "isoform_ac": "Q9W2V9-1", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAV1/entry#Q9W2V9-1", "sequence": { "sequence": "MAKSVGSACAQIAILLAITCSASELASAVLHQDTYEIVDTNLPNIAAYGVVPLRTDRLHRQRRTVPVSPPLPAVTTYRGAVSANATAEAGGAAGAGGGVAAETTVTTVDNKAAGGSVSYNVHNVGVNGTGQRKTYDVAPAVDSNTTSQMAPATKKPTLLGQSGNPKKVASSVVAATMTDPSPAVIDVDVSKVVDVPEEEIEAAVKNASLKESVDFHEYYNSVLYENKDEVASLWTELKATPENIMLSSSHRRAMTVELKFDFPFYGHFVRNITVATGGFLYTGEYVHSWLAATQYIAPLMANFDTSMSNDSFVRLHDNGTAFTAVWENVTLQDKPDFGKFTFSVTLYQSGDIVFAYMLVPTNINSIQDKEHPVKVGLSDAYIIDKQLFFARRKTIYEYHRVTFQQHEITNNTIIKLAAQPTCLGYNDCNSCINHNTTFTCLWCSVLNRCSTGTDRKKHEWLQMGCEATAIHTSSLCPALGDKGNNAAGQGKNGSANSGASANGATNTSTSSSGSSTPVTEPSVMSTRAPHATAYIKPGVDHSSDIHADGKVGNAELSKAEADNKNVGVAFGFMVPICLVFAVTLWLFYAYRNPHTKSGQLLIQFRPSQWSWRRGEARYTAATIHM", "length": 625, "header": "tr|Q9W2V9-1|A0ACD4DAV1_DROME Computationally mapped isoform of Lethal (1) G0289, isoform D OS=Drosophila melanogaster OX=7227 GN=l(1)G0289 PE=1 SV=1 CANONICAL=A0ACD4DAV1-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 157, "start_aa": "Thr", "end_pos": 157, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr157", "evidence": [ { "id": "40245499", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40245499" }, { "id": "A0ACD4DAV1", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A0ACD4DAV1" } ], "filter_code": "00000000000000001000.0000000.00000001000000.1000000.0100000000.110100100001111011.10000.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_reported_with_glycan" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W2V9", "url": "https://www.uniprot.org/uniprotkb/Q9W2V9" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q9W2V9", "url": "https://www.uniprot.org/uniprotkb/Q9W2V9" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2V9", "url": "https://www.uniprot.org/uniprotkb/Q9W2V9" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2V9", "url": "https://www.uniprot.org/uniprotkb/Q9W2V9" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W2V9", "url": "https://www.uniprot.org/uniprotkb/Q9W2V9" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q9W2V9", "url": "https://www.uniprot.org/uniprotkb/Q9W2V9" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q9W2V9", "url": "https://www.uniprot.org/uniprotkb/Q9W2V9" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2V9", "url": "https://www.uniprot.org/uniprotkb/Q9W2V9" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W2V9", "url": "https://www.uniprot.org/uniprotkb/Q9W2V9" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W2V9", "url": "https://www.uniprot.org/uniprotkb/Q9W2V9" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q9W2V9", "url": "https://www.uniprot.org/uniprotkb/Q9W2V9" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] }, { "title": "Quantitative and site-specific chemoproteomic profiling of O-GlcNAcylation in Drosophila.", "journal": "Bioorganic & medicinal chemistry", "date": "2025-04-10", "authors": "Lei Cong, Chen Zihan, Hao Yi, Huang Wanping, Chu Tianyu, Xiao Kangming, Zhang Che, Zhou Wen, Li Chenjian, Chen Xing", "evidence": [ { "database": "O-GlcNAc Database", "id": "A0ACD4DAV1", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A0ACD4DAV1" } ], "reference": [ { "type": "PubMed", "id": "40245499", "url": "https://glygen.org/publication/PubMed/40245499" } ] } ], "pathway": [ { "id": "dme:Dmel_CG2221", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG2221", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LUU7-1", "protein_name": "Plexin domain containing 2", "gene_name": "Plxdc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLFGCGWLMSEESLESFSKLVSLVFSKSRKLHIVSGKEKVCLASCSSAEDWKYVVANTSPQSEEGVEVDSQAYSHRWKRNVDPFKAVDTNRASMGQDSPESRGFPDLLLDDGQDNTTQIEEDTDHNYYISRIYGPADSASRDLWVNIDQMEKDKVKIHGILSNTHRQAARVNLSFDFPFYGHFLNEVTVATGGFIYTGEVVHRMLTATQYIAPLMANFDPSVSRNSTVRYFDNGTALVVQWDHVHLQDNYNLGSFTFQATLLMDGRIIFGYKEIPVLVTQISSTNHPVKVGLSDAFVVVHRIQQIPNVRRRTIYEYHRVELQMSKITNISAVEMTPLPTCLQFNGCGPCVSSQIGFNCSWCSKLQRCSSGFDRHRQDWVDSGCPEEVQSKEKMCENTEPGETSQTTTTAQTTTTQFRVLTTTRRAVTSHMPTSLPTEDDTKIALHLKDSGASTDDSAAEKKGGTLHAGLIVGILILVLIIAAAILVTVYMYHHPTSAASIFFIERRPSRWPAMKFRRGSGHPAYAEVEPVGEKEGFIVSEQC", "length": 542 }, "evidence": [ { "id": "HGNC:21013", "url": "https://alliancegenome.org/gene/HGNC:21013#orthology", "database": "AGR" }, { "id": "MGI:1914698", "url": "https://alliancegenome.org/gene/MGI:1914698#orthology", "database": "AGR" }, { "id": "RGD:1305962", "url": "https://alliancegenome.org/gene/RGD:1305962#orthology", "database": "AGR" }, { "id": "FB:FBgn0028331", "url": "https://alliancegenome.org/gene/FB:FBgn0028331#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZEE4-1", "protein_name": "Plexin domain containing 1", "gene_name": "Plxdc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRRGPGSCGVRRGAPGGGDPGVAPRPLGPPARAPQGRNAAHRSRCPLRSGSPFSQPRVASSTAAAAAPTRRSSAPTMRAQLWLLQLLLLCGTARALSPATPAGHDERQGSAWTAKRTRQGWNRRVRESPGQVLKPGKTQLSQDLGGDSLAIDTLPDNRTRVVEDNHNYYVSRVYGPGEQRTRDLWVDLSVANRNHVKVHRILSSSHRQASRVVLSFDFPFYGHPLRQITIATGGFIFMGDVLHRMLTATQYVAPLMANFNPGYSDNSTVAYFDNGTVFVVQWDHVYLQGREDRGSFTFQAALHQDGRIVFGYKEIPMAVLDISSAQHPVKAGLSDAFMILNSSPEVPESRRRTIFEYHRVELDSSKITTTSAVEFTPLPTCLQHQSCDACMSSNLTFNCSWCYVLQRCSSGFDRYRQEWLTYGCAQEAEGKTCEHFQDEGHYSASPDSSFSPSDGGSTTSSSLFIDSLTTEDDTKLNPYAEGDGLPDNSSPKTKGPPVHLGTIVGIVLAVLLVAAIILAGIYISGHPNSNAALFFIERRPHHWPAMKFHNHPNHSTYTEVEPSGHEKEGFVEAEQC", "length": 577 }, "evidence": [ { "id": "RGD:1307496", "url": "https://alliancegenome.org/gene/RGD:1307496#orthology", "database": "AGR" }, { "id": "HGNC:20945", "url": "https://alliancegenome.org/gene/HGNC:20945#orthology", "database": "AGR" }, { "id": "MGI:1919574", "url": "https://alliancegenome.org/gene/MGI:1919574#orthology", "database": "AGR" }, { "id": "FB:FBgn0028331", "url": "https://alliancegenome.org/gene/FB:FBgn0028331#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1R5J7-1", "protein_name": "Plexin domain-containing protein 2 isoform X1", "gene_name": "plxdc2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MALPARPHVFLGIFAVIQIKFTFQDLSSSGVSCFTFERPSKQEDAGVNLTFDSKRQRRWMFTSKPEVEISQNQELKRYVEHGRLDSERFPEVVTNESHDNLSIKRDMDHIYYTSKFYKLTDSSHKDLWVNIEKMDTGKVHEILSNTHRQTLRVNMSFDFPFYGHSLRKIYVATGGFIYTGDVVHKMLTATQYIAPLMANFDLSISQNSTVIYCDNGTALVVQWERVHLQDEALLGSFTFQAALYADGRITFAYKEIPVDISKISSVDHPVKVGLSDAFVVLHNIEQLPNVWRRTIYEYHRVELLKSKITNATAVEMLPLPTCLQFSSCETCVTAQIGFNCSWCSRLQRCSSGFDQYRQDWVDNGCLSEIKTQSCDRKQSLVSSTPPGKTGLTAASLTTTTSTTSASSLTGNVTGTDLFMTNLSTSLFTDDGEMGILEKQSEEQMQTGLLIGILLTMVLMVLAVLATIYMYNHPTSSASLFFIERRPTHWPAMKFRRGSGHPSYAEVEATGQDKEGFIMMDSRDSFLLADRRESLFLTEPKEGFIVSDQRECFVIMEHR", "length": 558 }, "evidence": [ { "id": "HGNC:21013", "url": "https://alliancegenome.org/gene/HGNC:21013#orthology", "database": "AGR" }, { "id": "MGI:1914698", "url": "https://alliancegenome.org/gene/MGI:1914698#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6UX71-1", "protein_name": "Plexin domain-containing protein 2", "gene_name": "PLXDC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARFPKADLAAAGVMLLCHFFTDQFQFADGKPGDQILDWQYGVTQAFPHTEEEVEVDSHAYSHRWKRNLDFLKAVDTNRASVGQDSPEPRSFTDLLLDDGQDNNTQIEEDTDHNYYISRIYGPSDSASRDLWVNIDQMEKDKVKIHGILSNTHRQAARVNLSFDFPFYGHFLREITVATGGFIYTGEVVHRMLTATQYIAPLMANFDPSVSRNSTVRYFDNGTALVVQWDHVHLQDNYNLGSFTFQATLLMDGRIIFGYKEIPVLVTQISSTNHPVKVGLSDAFVVVHRIQQIPNVRRRTIYEYHRVELQMSKITNISAVEMTPLPTCLQFNRCGPCVSSQIGFNCSWCSKLQRCSSGFDRHRQDWVDSGCPEESKEKMCENTEPVETSSRTTTTVGATTTQFRVLTTTRRAVTSQFPTSLPTEDDTKIALHLKDNGASTDDSAAEKKGGTLHAGLIIGILILVLIVATAILVTVYMYHHPTSAASIFFIERRPSRWPAMKFRRGSGHPAYAEVEPVGEKEGFIVSEQC", "length": 529 }, "evidence": [ { "id": "HGNC:21013", "url": "https://alliancegenome.org/gene/HGNC:21013#orthology", "database": "AGR" }, { "id": "MGI:1914698", "url": "https://alliancegenome.org/gene/MGI:1914698#orthology", "database": "AGR" }, { "id": "RGD:1305962", "url": "https://alliancegenome.org/gene/RGD:1305962#orthology", "database": "AGR" }, { "id": "FB:FBgn0028331", "url": "https://alliancegenome.org/gene/FB:FBgn0028331#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8IUK5-1", "protein_name": "Plexin domain-containing protein 1", "gene_name": "PLXDC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRGELWLLVLVLREAARALSPQPGAGHDEGPGSGWAAKGTVRGWNRRARESPGHVSEPDRTQLSQDLGGGTLAMDTLPDNRTRVVEDNHSYYVSRLYGPSEPHSRELWVDVAEANRSQVKIHTILSNTHRQASRVVLSFDFPFYGHPLRQITIATGGFIFMGDVIHRMLTATQYVAPLMANFNPGYSDNSTVVYFDNGTVFVVQWDHVYLQGWEDKGSFTFQAALHHDGRIVFAYKEIPMSVPEISSSQHPVKTGLSDAFMILNPSPDVPESRRRSIFEYHRIELDPSKVTSMSAVEFTPLPTCLQHRSCDACMSSDLTFNCSWCHVLQRCSSGFDRYRQEWMDYGCAQEAEGRMCEDFQDEDHDSASPDTSFSPYDGDLTTTSSSLFIDSLTTEDDTKLNPYAGGDGLQNNLSPKTKGTPVHLGTIVGIVLAVLLVAAIILAGIYINGHPTSNAALFFIERRPHHWPAMKFRSHPDHSTYAEVEPSGHEKEGFMEAEQC", "length": 500 }, "evidence": [ { "id": "RGD:1307496", "url": "https://alliancegenome.org/gene/RGD:1307496#orthology", "database": "AGR" }, { "id": "HGNC:20945", "url": "https://alliancegenome.org/gene/HGNC:20945#orthology", "database": "AGR" }, { "id": "MGI:1919574", "url": "https://alliancegenome.org/gene/MGI:1919574#orthology", "database": "AGR" }, { "id": "FB:FBgn0028331", "url": "https://alliancegenome.org/gene/FB:FBgn0028331#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q91ZV7-1", "protein_name": "Plexin domain-containing protein 1", "gene_name": "Plxdc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRAQLWLLQLLLLRGAARALSPATPAGHNEGQDSAWTAKRTRQGWSRRPRESPAQVLKPGKTQLSQDLGGGSLAIDTLPDNRTRVVEDNHNYYVSRVYGPGEKQSQDLWVDLAVANRSHVKIHRILSSSHRQASRVVLSFDFPFYGHPLRQITIATGGFIFMGDMLHRMLTATQYVAPLMANFNPGYSDNSTVAYFDNGTVFVVQWDHVYLQDREDRGSFTFQAALHRDGRIVFGYKEIPMAVLDISSAQHPVKAGLSDAFMILNSSPEVPASQRRTIFEYHRVELDSSKITTTSAVEFTPLPTCLQHQSCDTCVSSNLTFNCSWCHVLQRCSSGFDRYRQEWLTYGCAQEAEGKTCEDFQDDSHYSASPDSSFSPFNGDSTTSSSLFIDSLTTEDDTKLNPYAEGDGLPDHSSPKSKGPPVHLGTIVGIVLAVLLVAAIILAGIYISGHPNSNAALFFIERRPHHWPAMKFHNHPNHSTYTEVEPSGHEKEGFVEAEQC", "length": 500 }, "evidence": [ { "id": "RGD:1307496", "url": "https://alliancegenome.org/gene/RGD:1307496#orthology", "database": "AGR" }, { "id": "HGNC:20945", "url": "https://alliancegenome.org/gene/HGNC:20945#orthology", "database": "AGR" }, { "id": "MGI:1919574", "url": "https://alliancegenome.org/gene/MGI:1919574#orthology", "database": "AGR" }, { "id": "FB:FBgn0028331", "url": "https://alliancegenome.org/gene/FB:FBgn0028331#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9DC11-1", "protein_name": "Plexin domain-containing protein 2", "gene_name": "Plxdc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARFRRADLAAAGVMLLCHFLTDRFQFAHGEPGHHTNDWIYEVTNAFPWNEEGVEVDSQAYNHRWKRNVDPFKAVDTNRASMGQASPESKGFTDLLLDDGQDNNTQIEEDTDHNYYISRIYGPADSASRDLWVNIDQMEKDKVKIHGILSNTHRQAARVNLSFDFPFYGHFLNEVTVATGGFIYTGEVVHRMLTATQYIAPLMANFDPSVSRNSTVRYFDNGTALVVQWDHVHLQDNYNLGSFTFQATLLMDGRIIFGYKEIPVLVTQISSTNHPVKVGLSDAFVVVHRIQQIPNVRRRTIYEYHRVELQMSKITNISAVEMTPLPTCLQFNGCGPCVSSQIGFNCSWCSKLQRCSSGFDRHRQDWVDSGCPEEVQSKEKMCEKTEPGETSQTTTTSHTTTMQFRVLTTTRRAVTSQMPTSLPTEDDTKIALHLKDSGASTDDSAAEKKGGTLHAGLIVGILILVLIIAAAILVTVYMYHHPTSAASIFFIERRPSRWPAMKFRRGSGHPAYAEVEPVGEKEGFIVSEQC", "length": 530 }, "evidence": [ { "id": "HGNC:21013", "url": "https://alliancegenome.org/gene/HGNC:21013#orthology", "database": "AGR" }, { "id": "MGI:1914698", "url": "https://alliancegenome.org/gene/MGI:1914698#orthology", "database": "AGR" }, { "id": "RGD:1305962", "url": "https://alliancegenome.org/gene/RGD:1305962#orthology", "database": "AGR" }, { "id": "FB:FBgn0028331", "url": "https://alliancegenome.org/gene/FB:FBgn0028331#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAV1", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAV1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 127, "end_pos": 129, "annotation": "n_glycosylation_sequon" }, { "start_pos": 144, "end_pos": 146, "annotation": "n_glycosylation_sequon" }, { "start_pos": 206, "end_pos": 208, "annotation": "n_glycosylation_sequon" }, { "start_pos": 271, "end_pos": 273, "annotation": "n_glycosylation_sequon" }, { "start_pos": 309, "end_pos": 311, "annotation": "n_glycosylation_sequon" }, { "start_pos": 318, "end_pos": 320, "annotation": "n_glycosylation_sequon" }, { "start_pos": 328, "end_pos": 330, "annotation": "n_glycosylation_sequon" }, { "start_pos": 410, "end_pos": 412, "annotation": "n_glycosylation_sequon" }, { "start_pos": 435, "end_pos": 437, "annotation": "n_glycosylation_sequon" }, { "start_pos": 492, "end_pos": 494, "annotation": "n_glycosylation_sequon" }, { "start_pos": 506, "end_pos": 508, "annotation": "n_glycosylation_sequon" }, { "start_pos": 84, "end_pos": 86, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": 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"categories": [ "Protein Classification" ] }, { "id": "PF13903", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13903", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001400987", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001400987", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q2MGK8", "url": "https://www.uniprot.org/uniprotkb/Q2MGK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q2MGK8-1", "url": "https://www.uniprot.org/uniprotkb/Q2MGK8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRDYPSVPNVFRVASTHSINSENPYNNIRPANVICNTTERPPIAIHQLTTSASIEHSHPSQQAQHQQQQLLHHQQQHHHQQHSPYATLPRGQRLAPQQHQQAGVINTISGSIPATGFSSLAGSFSDLQLNNIGNHSSNSRSNHNSISNNRRQQQQQQQQQQQRLVPHLSRHQPAIEVQQTQQHQQTQQQHVQRQQQQERLASGGAGATDPQGGISNMTTVNGGYLWLITPVAASISVAIVIAALAGPQWLFTEEKLPNANYNGTANFKALDDGAYITKYTKSSLWILCTTLPGLDADSYNCVKIDYFSNEGYQPDPHDSTAAIPYTVTKSCPIFLAAGVFLVISFIVFLIPTCSHQNNLYYFSAGILFIVSGLVMLIGLIAYISILKAEIGSKLRPRSTLQPALIKVSYGQSFFLFVFGFIVTEFVGVLNIFLFINLQEVSYYSRLPCFSVANIHAKLKEGQHPLSDSYKRYKQPGITTASQEGLSSAGQGQQGHQSHHPTHQPHPTAQPPHGILRSGNSRLHQVYDAGRGHPGMTGQIGHSGQTQTLPGACRKHPNAGSNLNLYLHNDLERRFYFEKPAVSKCNLHSRSFAKSLNELCTDTSVSSTHVPAPLLPSAADPLPAPALFADLPQEFPLTRSVSTATEIYPASSSAPAPPSAQMKRKQQRNMATNTNTKISNNPPSSNSQMADQSRLCGLKRGLRKTKDELFQEFCRRAGMRSKPKNIYYISGGDEAEEEEQEDQAKREEVPDDPHRDDDDDADGDDHGFRQFNRMEEEHLYVVGDHAQLVVPRRTSMCVDSMGQPLRRLNSNLSLHTDLSFPGTGGYPGMRMSLPQPADLGQSRTLPRCFLRQSSDSLASQGYPLGSSQQRFSQLMLNQQQNRFVSSTLTLPQVVAPKSQVQWPTAIPSSPSNYSNGYQQHPQPIYPAPTSGSGAPGTTASVSGPPKFQRGYAFDDQQRRSSFVSDAFDLDEIERERRRSHASLFGMGQVRDPYDLINGTAV", "length": 1000, "header": "tr|Q2MGK8-1|Q2MGK8_DROME Isoform 1 of Stargazin-like protein OS=Drosophila melanogaster OX=7227 GN=stg1 PE=4 SV=1 CANONICAL=Q2MGK8-1" }, "isoforms": [ { "isoform_ac": "Q2MGK8-1", "url": "https://www.uniprot.org/uniprotkb/Q2MGK8/entry#Q2MGK8-1", "sequence": { "sequence": "MRDYPSVPNVFRVASTHSINSENPYNNIRPANVICNTTERPPIAIHQLTTSASIEHSHPSQQAQHQQQQLLHHQQQHHHQQHSPYATLPRGQRLAPQQHQQAGVINTISGSIPATGFSSLAGSFSDLQLNNIGNHSSNSRSNHNSISNNRRQQQQQQQQQQQRLVPHLSRHQPAIEVQQTQQHQQTQQQHVQRQQQQERLASGGAGATDPQGGISNMTTVNGGYLWLITPVAASISVAIVIAALAGPQWLFTEEKLPNANYNGTANFKALDDGAYITKYTKSSLWILCTTLPGLDADSYNCVKIDYFSNEGYQPDPHDSTAAIPYTVTKSCPIFLAAGVFLVISFIVFLIPTCSHQNNLYYFSAGILFIVSGLVMLIGLIAYISILKAEIGSKLRPRSTLQPALIKVSYGQSFFLFVFGFIVTEFVGVLNIFLFINLQEVSYYSRLPCFSVANIHAKLKEGQHPLSDSYKRYKQPGITTASQEGLSSAGQGQQGHQSHHPTHQPHPTAQPPHGILRSGNSRLHQVYDAGRGHPGMTGQIGHSGQTQTLPGACRKHPNAGSNLNLYLHNDLERRFYFEKPAVSKCNLHSRSFAKSLNELCTDTSVSSTHVPAPLLPSAADPLPAPALFADLPQEFPLTRSVSTATEIYPASSSAPAPPSAQMKRKQQRNMATNTNTKISNNPPSSNSQMADQSRLCGLKRGLRKTKDELFQEFCRRAGMRSKPKNIYYISGGDEAEEEEQEDQAKREEVPDDPHRDDDDDADGDDHGFRQFNRMEEEHLYVVGDHAQLVVPRRTSMCVDSMGQPLRRLNSNLSLHTDLSFPGTGGYPGMRMSLPQPADLGQSRTLPRCFLRQSSDSLASQGYPLGSSQQRFSQLMLNQQQNRFVSSTLTLPQVVAPKSQVQWPTAIPSSPSNYSNGYQQHPQPIYPAPTSGSGAPGTTASVSGPPKFQRGYAFDDQQRRSSFVSDAFDLDEIERERRRSHASLFGMGQVRDPYDLINGTAV", "length": 1000, "header": "tr|Q2MGK8-1|Q2MGK8_DROME Isoform 1 of Stargazin-like protein OS=Drosophila melanogaster OX=7227 GN=stg1 PE=4 SV=1 CANONICAL=Q2MGK8-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 928, "start_aa": "Thr", "end_pos": 928, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr928", "evidence": [ { "id": "GLY_001163", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001163" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q2MGK8", "url": "https://www.uniprot.org/uniprotkb/Q2MGK8" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "Q2MGK8", "url": "https://www.uniprot.org/uniprotkb/Q2MGK8" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q2MGK8", "url": "https://www.uniprot.org/uniprotkb/Q2MGK8" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q2MGK8", "url": "https://www.uniprot.org/uniprotkb/Q2MGK8" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q2MGK8", "url": "https://www.uniprot.org/uniprotkb/Q2MGK8" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "Q2MGK8", "url": "https://www.uniprot.org/uniprotkb/Q2MGK8" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "Q2MGK8", "url": "https://www.uniprot.org/uniprotkb/Q2MGK8" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q2MGK8", "url": "https://www.uniprot.org/uniprotkb/Q2MGK8" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "Q2MGK8", "url": "https://www.uniprot.org/uniprotkb/Q2MGK8" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q2MGK8", "url": "https://www.uniprot.org/uniprotkb/Q2MGK8" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "Q2MGK8", "url": "https://www.uniprot.org/uniprotkb/Q2MGK8" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [ { "id": "dme:Dmel_CG46498", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dme:Dmel_CG46498", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4INZ4-1", "protein_name": "Calcium channel, voltage-dependent, gamma subunit 2b", "gene_name": "cacng2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGVFERGVQMLLTTVGAFAAFSLMTIAVGTDYWLYSRGVCKIKSTNENETSKKNEEVMTHSGLWRTCCLEGNFKGMCKQIDHFPEDADYEADASEYFLRAVRASSIFPILSVILLFMGGLCVAASEFYKSRHNIILSAGIFFVSAGLSNIIGIIVYISANAGDPSKSDSKKNSYSYGWSFYFGALSFIMAEMVGVLAVHMFIDRHRELRVAQARVRGADYLQGAAITRIPSYRYRYRRSSRSSSRSTDPSHSRDTSPVGLKGFAALPSTDISMYTLSRGGGDTLKTPHGTPPMYNSDREAEFLQVHNCIPKDSKDRRTTPV", "length": 321 }, "evidence": [ { "id": "HGNC:1406", "url": "https://alliancegenome.org/gene/HGNC:1406#orthology", "database": "AGR" }, { "id": "MGI:1316660", "url": "https://alliancegenome.org/gene/MGI:1316660#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1P8P0-1", "protein_name": "Calcium channel, voltage-dependent, gamma subunit 8a", "gene_name": "cacng8a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDGKARHIPPAMVWCERGIQVLLTTVGAFAAFALMTVAIGTDYWLYARAFICNSTANSSQDDPHNKDKKDPGALTHSGLWRICCLEGLKRGVCSQINHFPEDADYDQDAAEYLLRVVRASSIFPILSAILLLLGGVCVASSRFYKTKRHIILGAGILFVVAGLSNIIGVIVYISAALSDISPKKDEDKKWHYSYGWSFYFGGLSFILAEVVGVLAVNIYIERNKELRCRSRTDLFRSTTSAVLRLPGYRFRRRSSRSSSRSTAEPSRSREQSPTSAIAPKNFGPPLAAGPPPFSVATLPNPHTHSGGGGGGGGGGGMGDISMYTLGREGKPPMYGTVDRATLYQLHNYFPTKEGGGGGALMTGTLPSISKSNLAASANATLNTSSSSGPQQAPLSAGSSATMERDRGLGTLDRLGKGDSSNTNTLNRRTTPV", "length": 432 }, "evidence": [ { "id": "HGNC:13628", "url": "https://alliancegenome.org/gene/HGNC:13628#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050417-239", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-239#orthology", "database": "AGR" }, { "id": "MGI:1932376", "url": "https://alliancegenome.org/gene/MGI:1932376#orthology", "database": "AGR" }, { "id": "RGD:628808", "url": "https://alliancegenome.org/gene/RGD:628808#orthology", "database": "AGR" }, { "id": "FB:FBgn0288700", "url": "https://alliancegenome.org/gene/FB:FBgn0288700#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58HJA9-1", "protein_name": "Voltage-dependent calcium channel gamma-7 subunit", "gene_name": "cacng7b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRMSSCSSRALTLLSTVFGACGLLLVGVAVATDYWLLMEEGIVLQQNQTVDVKMALHSGLWRVCFIAGTEKGRCVASEYFTEPEIEITTENTANILKMVRTATPFPMVSLLFVFTAFIISNVGHIRPQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPREPEQFFNYRYGWSFAFAASSFLLKEGAGVMSVYLFMKRYAEEEMYRPHPTLYRPRLSEGSDYSGQYLHPETWPPPQRARSASEISSDISIQLTQNPQHPSKASGQQGTSSPGITAASSPASGTGYQLPSPGSAAPYPHNHPLHPGAHGPAAASQAMPMSAPPAAVPPPHYHTHMRMSASPC", "length": 348 }, "evidence": [ { "id": "HGNC:13626", "url": "https://alliancegenome.org/gene/HGNC:13626#orthology", "database": "AGR" }, { "id": "MGI:1932374", "url": "https://alliancegenome.org/gene/MGI:1932374#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ACD6B6W8-1", "protein_name": "Voltage-dependent calcium channel gamma-5 subunit", "gene_name": "cacng5b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSACGRKALTLLSSVFAVCSLGLLGIAVSTDYWLYLEEGVILPLNQSTDMRMSIHSGLWRVCFLAGEERGRCFTIEYVMPMSVQLTSESTVSVLKMIRSATPFPLVSLFFMFIGFVLNNIGHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMFNRTKSNEAYFSYKYGWSFAFAAISFLLTESAGVMSVYLFMKRYTAEEIYQPHPSFYRPRLSNCSDYSGQFLHPEAWTRGRSPSDLSSDTSLQMNASYPALLKCPDYDQVSSSPC", "length": 275 }, "evidence": [ { "id": "HGNC:1409", "url": "https://alliancegenome.org/gene/HGNC:1409#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120104-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120104-3#orthology", "database": "AGR" }, { "id": "MGI:2157946", "url": "https://alliancegenome.org/gene/MGI:2157946#orthology", "database": "AGR" }, { "id": "RGD:628805", "url": "https://alliancegenome.org/gene/RGD:628805#orthology", "database": "AGR" }, { "id": "FB:FBgn0288700", "url": "https://alliancegenome.org/gene/FB:FBgn0288700#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ACD6B7X1-1", "protein_name": "Voltage-dependent calcium channel gamma-4 subunit", "gene_name": "cacng4a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAWCDRRVQTVLTSLGALAAISLMSVAIGTDYWLYSRAHICNTTSNSTDETQNLLLPKKTRGDLTHSGLWKICCIEGINNGSCYWINHFSVEDYDTENSEYILRLVRASSLFPILSTILLLLGGVCVGIGHIYSSRNNITLSAGILFVSAGLSNIIGIIVYISSNAGDPGDKKGEDKKNLYSYGWSFYSGVLSFILAETIAVLAVNIYIEKNKEVHFKHFVFNKTTPSPSSSIYTTIPSYHYKQQRSHSCSQSRDPFKNTSSVTHGVISSSLPLVDISMYALGGEHPLLVGGQVSYNTDLEHHNFRKVHNHIPKDVKDNLNRRITPV", "length": 327 }, "evidence": [ { "id": "HGNC:1408", "url": "https://alliancegenome.org/gene/HGNC:1408#orthology", "database": "AGR" }, { "id": "MGI:1859167", "url": "https://alliancegenome.org/gene/MGI:1859167#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7EXE2-1", "protein_name": "Calcium channel, voltage-dependent, gamma subunit 5a", "gene_name": "cacng5a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGLCGRKVLTLLSSVFAVCSLGLLGIAVSTDYWLYLEEGVILPLNQSTEIRMSLHSGLWRVCFLSESPASGTVLPTGKSGDEKGRCFTIEYVMPMNVQMTSESTASVLKMIRSATPFPLVSLFFMFIGFVLSNIGHIRPQRTILAFISGIFFILSGLSLVVGLVLYISSINDEMLNRTKTNEAYFSYKYGWSFAFAAVSFLLTEAAGVMSVYLFMKRYTAEEMYRPHPGFYRPRLSNCSDYSGQFLHPDAWTRGRSPSDISSEASLQMNSNFPALLKCPDYDQMSSSPC", "length": 289 }, "evidence": [ { "id": "HGNC:1409", "url": "https://alliancegenome.org/gene/HGNC:1409#orthology", "database": "AGR" }, { "id": "MGI:2157946", "url": "https://alliancegenome.org/gene/MGI:2157946#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7EY10-1", "protein_name": "Voltage-dependent calcium channel gamma-3 subunit", "gene_name": "cacng3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLMCDRGVQMLITTVGAFAAFSLMTIAVGTDYWLYSRGVCRVKSNNENETSRKNEEVMTHSGLWRTCCLEGTFRGVCKKIDHFPEDADYEQDAAEYLLRAVRASSIFPIMSVGLLFMGGLCVAASEFYRSRHNVILSAGIFFVSAGLSNIIGIIVYISANSGDPGQSDSKKSYSYGWSFYFGALSFIMAEMVGVLAVHMFIEKHRKLRAKSRTELIKKSAFSRIPSYRYRFRRRSSCRSSEPASRDASPMGKSGYTGPAAADISMYTLSRDPSKAAMGALLNSEREFLQAHNSNAKDFKDAANRRTTPV", "length": 309 }, "evidence": [ { "id": "HGNC:1407", "url": "https://alliancegenome.org/gene/HGNC:1407#orthology", "database": "AGR" }, { "id": "MGI:1859165", "url": "https://alliancegenome.org/gene/MGI:1859165#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FGK7-1", "protein_name": "Voltage-dependent calcium channel gamma-4 subunit", "gene_name": "cacng4b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAWCERGIQMLLATVGAFVAFSLMSIAIGTDYWLYSRAYICNATNASADETQTQPKKVRGDLTHSGLWRICCIEGLNKGSCYRINHFPDDNDYDTDSSEYLLRIVRASSVFPLLSTILLLLGGLCVGIGRIYNKRNNILLSAGILFVAAGLSNIIGIIVYISSNAGDPSDKRDEDKKNQYNYGWSFYFGALSFIVAEAVAVLAVNIYIEKNKEVRFKARREFIKSTSSSSPYSRMPSFRYRRRHSRSSSRSTEASREASPVGMKMISSVPVGEINMYTLTRDPLKSGTDSSYSPDHDSGFLQVHNCFPKDLNDGANRRTTPV", "length": 322 }, "evidence": [ { "id": "HGNC:1408", "url": "https://alliancegenome.org/gene/HGNC:1408#orthology", "database": "AGR" }, { "id": "MGI:1859167", "url": "https://alliancegenome.org/gene/MGI:1859167#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9QCW1-1", "protein_name": "Voltage-dependent calcium channel gamma-4 subunit isoform X1", "gene_name": "cacng8b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVCEKGIQILLTIVGAFASFGLMTVAIGTDYWLYSRALICNSTANNTQEDPHNKDKKDPGALTHSGLWRICCLEGVKRGVCSQINHFPEDADFDHDGAEYVLRVVRASNIFPILSAILLLMGGVCIAASRFYKSKRNIVLGAGILFVAAGLSNIIGVIVYISAALGDISPKKDEDKKWQYSYGWSFYFGGLSFILAEMVGVLAVNIYIEKNKELRCRTRTDIFKSTTHAMLRLPSYRFRRRSRSSSRSTDPSRSRDPSPVGGPPGGKNFGMPPSALLSQGPISVSTLPNPHSRSALPGGDISLYTLSRDPKLGGIGGLGAPPLYGTVDRATLYQLHNCFPKEGGGGMMMSGTLPSLKSHNPSGVQNSSNSNAPLSNSVPSSQPPPFSSSTGERDRGMGTLDRLGKGDRESNSNTLNRKTTPV", "length": 422 }, "evidence": [ { "id": "HGNC:13628", "url": "https://alliancegenome.org/gene/HGNC:13628#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100921-72", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100921-72#orthology", "database": "AGR" }, { "id": "MGI:1932376", "url": "https://alliancegenome.org/gene/MGI:1932376#orthology", "database": "AGR" }, { "id": "RGD:628808", "url": "https://alliancegenome.org/gene/RGD:628808#orthology", "database": "AGR" }, { "id": "FB:FBgn0288700", "url": "https://alliancegenome.org/gene/FB:FBgn0288700#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F6NW67-1", "protein_name": "Voltage-dependent calcium channel gamma-7 subunit", "gene_name": "cacng7a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSSFSTRALTLLSSVFGACGLLLVGVAVSTDYWLLMEEGIILQQNQTTEVKMALHSGLWRVCFVAGPEKGRCVASEYFTEPEIEITTENTANILKMVRTATPFPMVSLLFVFTAFVISNIGHIRPQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPREPEQFFHYHYGWSFAFAASSFLLKEGAGVMSVYLFMKRYAEEEMYRPHPALYRPRLSECSDYSGQYLHPDSWPPPQRGRSGSEVSSDISIQLNQTPLPPQTKGSGPSNPPSSSGPSSGASYHLPPASSSSSSSYPHTIHSSHSSSHVPQSLPMAAPPSAVPPPRYHAHMRMSASPC", "length": 341 }, "evidence": [ { "id": "HGNC:13626", "url": "https://alliancegenome.org/gene/HGNC:13626#orthology", "database": "AGR" }, { "id": "MGI:1932374", "url": "https://alliancegenome.org/gene/MGI:1932374#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O60359-1", "protein_name": "Voltage-dependent calcium channel gamma-3 subunit", "gene_name": "CACNG3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRMCDRGIQMLITTVGAFAAFSLMTIAVGTDYWLYSRGVCRTKSTSDNETSRKNEEVMTHSGLWRTCCLEGAFRGVCKKIDHFPEDADYEQDTAEYLLRAVRASSVFPILSVTLLFFGGLCVAASEFHRSRHNVILSAGIFFVSAGLSNIIGIIVYISANAGDPGQRDSKKSYSYGWSFYFGAFSFIIAEIVGVVAVHIYIEKHQQLRAKSHSEFLKKSTFARLPPYRYRFRRRSSSRSTEPRSRDLSPISKGFHTIPSTDISMFTLSRDPSKITMGTLLNSDRDHAFLQFHNSTPKEFKESLHNNPANRRTTPV", "length": 315 }, "evidence": [ { "id": "HGNC:1407", "url": "https://alliancegenome.org/gene/HGNC:1407#orthology", "database": "AGR" }, { "id": "MGI:1859165", "url": "https://alliancegenome.org/gene/MGI:1859165#orthology", "database": "AGR" }, { "id": "RGD:628803", "url": "https://alliancegenome.org/gene/RGD:628803#orthology", "database": "AGR" }, { "id": "FB:FBgn0288700", "url": "https://alliancegenome.org/gene/FB:FBgn0288700#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O88602-1", "protein_name": "Voltage-dependent calcium channel gamma-2 subunit", "gene_name": "Cacng2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLFDRGVQMLLTTVGAFAAFSLMTIAVGTDYWLYSRGVCKTKSVSENETSKKNEEVMTHSGLWRTCCLEGNFKGLCKQIDHFPEDADYEADTAEYFLRAVRASSIFPILSVILLFMGGLCIAASEFYKTRHNIILSAGIFFVSAGLSNIIGIIVYISANAGDPSKSDSKKNSYSYGWSFYFGALSFIIAEMVGVLAVHMFIDRHKQLRATARATDYLQASAITRIPSYRYRYQRRSRSSSRSTEPSHSRDASPVGVKGFNTLPSTEISMYTLSRDPLKAATTPTATYNSDRDNSFLQVHNCIQKDSKDSLHANTANRRTTPV", "length": 323 }, "evidence": [ { "id": "HGNC:1406", "url": "https://alliancegenome.org/gene/HGNC:1406#orthology", "database": "AGR" }, { "id": "MGI:1316660", "url": "https://alliancegenome.org/gene/MGI:1316660#orthology", "database": "AGR" }, { "id": "RGD:71095", "url": "https://alliancegenome.org/gene/RGD:71095#orthology", "database": "AGR" }, { "id": "FB:FBgn0288700", "url": "https://alliancegenome.org/gene/FB:FBgn0288700#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P62955-1", "protein_name": "Voltage-dependent calcium channel gamma-7 subunit", "gene_name": "CACNG7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSHCSSRALTLLSSVFGACGLLLVGIAVSTDYWLYMEEGTVLPQNQTTEVKMALHAGLWRVCFFAGREKGRCVASEYFLEPEINLVTENTENILKTVRTATPFPMVSLFLVFTAFVISNIGHIRPQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPSSSEQYFHYRYGWSFAFAASSFLLKEGAGVMSVYLFTKRYAEEEMYRPHPAFYRPRLSDCSDYSGQFLQPEAWRRGRSPSDISSDVSIQMTQNYPPAIKYPDHLHISTSPC", "length": 275 }, "evidence": [ { "id": "HGNC:13626", "url": "https://alliancegenome.org/gene/HGNC:13626#orthology", "database": "AGR" }, { "id": "MGI:1932374", "url": "https://alliancegenome.org/gene/MGI:1932374#orthology", "database": "AGR" }, { "id": "RGD:628807", "url": "https://alliancegenome.org/gene/RGD:628807#orthology", "database": "AGR" }, { "id": "FB:FBgn0288700", "url": "https://alliancegenome.org/gene/FB:FBgn0288700#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P62956-1", "protein_name": "Voltage-dependent calcium channel gamma-7 subunit", "gene_name": "Cacng7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSHCSSRALTLLSSVFGACGLLLVGIAVSTDYWLYMEEGTVLPQNQTTEVKMALHAGLWRVCFFAGREKGRCVASEYFLEPEINLVTENTENILKTVRTATPFPMVSLFLVFTAFVISNIGHIRPQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPSSSEQYFHYRYGWSFAFAASSFLLKEGAGVMSVYLFTKRYAEEEMYRPHPAFYRPRLSDCSDYSGQFLQPEAWRRGRSPSDISSDVSIQMTQNYPPAIKYPDHLHISTSPC", "length": 275 }, "evidence": [ { "id": "HGNC:13626", "url": "https://alliancegenome.org/gene/HGNC:13626#orthology", "database": "AGR" }, { "id": "MGI:1932374", "url": "https://alliancegenome.org/gene/MGI:1932374#orthology", "database": "AGR" }, { "id": "RGD:628807", "url": "https://alliancegenome.org/gene/RGD:628807#orthology", "database": "AGR" }, { "id": "FB:FBgn0288700", "url": "https://alliancegenome.org/gene/FB:FBgn0288700#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P62957-1", "protein_name": "Voltage-dependent calcium channel gamma-7 subunit", "gene_name": "Cacng7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSHCSSRALTLLSSVFGACGLLLVGIAVSTDYWLYMEEGTVLPQNQTTEVKMALHAGLWRVCFFAGREKGRCVASEYFLEPEINLVTENTENILKTVRTATPFPMVSLFLVFTAFVISNIGHIRPQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPSSSEQYFHYRYGWSFAFAASSFLLKEGAGVMSVYLFTKRYAEEEMYRPHPAFYRPRLSDCSDYSGQFLQPEAWRRGRSPSDISSDVSIQMTQNYPPAIKYPDHLHISTSPC", "length": 275 }, "evidence": [ { "id": "HGNC:13626", "url": "https://alliancegenome.org/gene/HGNC:13626#orthology", "database": "AGR" }, { "id": "MGI:1932374", "url": "https://alliancegenome.org/gene/MGI:1932374#orthology", "database": "AGR" }, { "id": "RGD:628807", "url": "https://alliancegenome.org/gene/RGD:628807#orthology", "database": "AGR" }, { "id": "FB:FBgn0288700", "url": "https://alliancegenome.org/gene/FB:FBgn0288700#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q71RJ2-1", "protein_name": "Voltage-dependent calcium channel gamma-2 subunit", "gene_name": "Cacng2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLFDRGVQMLLTTVGAFAAFSLMTIAVGTDYWLYSRGVCKTKSVSENETSKKNEEVMTHSGLWRTCCLEGNFKGLCKQIDHFPEDADYEADTAEYFLRAVRASSIFPILSVILLFMGGLCIAASEFYKTRHNIILSAGIFFVSAGLSNIIGIIVYISANAGDPSKSDSKKNSYSYGWSFYFGALSFIIAEMVGVLAVHMFIDRHKQLRATARATDYLQASAITRIPSYRYRYQRRSRSSSRSTEPSHSRDASPVGVKGFNTLPSTEISMYTLSRDPLKAATTPTATYNSDRDNSFLQVHNCIQKDSKDSLHANTANRRTTPV", "length": 323 }, "evidence": [ { "id": "HGNC:1406", "url": "https://alliancegenome.org/gene/HGNC:1406#orthology", "database": "AGR" }, { "id": "MGI:1316660", "url": "https://alliancegenome.org/gene/MGI:1316660#orthology", "database": "AGR" }, { "id": "RGD:71095", "url": "https://alliancegenome.org/gene/RGD:71095#orthology", "database": "AGR" }, { "id": "FB:FBgn0288700", "url": "https://alliancegenome.org/gene/FB:FBgn0288700#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8VHW2-1", "protein_name": "Voltage-dependent calcium channel gamma-8 subunit", "gene_name": "Cacng8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESLKRWNEERGLWCEKGVQVLLTTIGAFSAFGLMTIAISTDYWLYTRALICNTTNLTAGDDGPPHRGGSGSSEKKDPGGLTHSGLWRICCLEGLKRGVCVKINHFPEDTDYDHDSAEYLLRVVRASSIFPILSAILLLLGGVCVAASRVYKSKRNIILGAGILFVAAGLSNIIGVIVYISANAGEPGPKRDEEKKNHYSYGWSFYFGGLSFILAEVIGVLAVNIYIERSREAHCQSRSDLLKAGGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRGSSEASPSRDASPGGPGGPGFASTDISMYTLSRDPSKGSVAAGLASAGGGGSGAGVGAYGGAAGAAGGGGAGSERDRGSSAGFLTLHNAFPKEAASGVTVTVTGPPAAPAPAPAPPAPAAPAPGTLSKEAAASNTNTLNRKTTPV", "length": 423 }, "evidence": [ { "id": "HGNC:13628", "url": "https://alliancegenome.org/gene/HGNC:13628#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100921-72", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100921-72#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050417-239", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-239#orthology", "database": "AGR" }, { "id": "MGI:1932376", "url": "https://alliancegenome.org/gene/MGI:1932376#orthology", "database": "AGR" }, { "id": "RGD:628808", "url": "https://alliancegenome.org/gene/RGD:628808#orthology", "database": "AGR" }, { "id": "FB:FBgn0288700", "url": "https://alliancegenome.org/gene/FB:FBgn0288700#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VHW4-1", "protein_name": "Voltage-dependent calcium channel gamma-5 subunit", "gene_name": "Cacng5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSACGRKALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGIILPQNQSTEVKMSLHSGLWRVCFLAGEERGRCFTIEYVMPMNSQMTSESTVNVLKMIRSATPFPLVSLFFMFIGFILSNIGHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYKYGWSFAFAAISFLLTESAGVMSVYLFMKRYTAEDMYRPHPGFYRPRLSNCSDYSGQFLHPDAWIRGRSPSDISSDASLQMNSNYPALLKCPDYDQMSSSPC", "length": 275 }, "evidence": [ { "id": "HGNC:1409", "url": "https://alliancegenome.org/gene/HGNC:1409#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120104-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120104-3#orthology", "database": "AGR" }, { "id": "MGI:2157946", "url": "https://alliancegenome.org/gene/MGI:2157946#orthology", "database": "AGR" }, { "id": "RGD:628805", "url": "https://alliancegenome.org/gene/RGD:628805#orthology", "database": "AGR" }, { "id": "FB:FBgn0288700", "url": "https://alliancegenome.org/gene/FB:FBgn0288700#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VHW5-1", "protein_name": "Voltage-dependent calcium channel gamma-8 subunit", "gene_name": "Cacng8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESLKRWNEERGLWCEKGVQVLLTTIGAFAAFGLMTIAISTDYWLYTRALICNTTNLTAGDDGPPHRGGSGSSEKKDPGGLTHSGLWRICCLEGLKRGVCVKINHFPEDTDYDHDSAEYLLRVVRASSIFPILSAILLLLGGVCVAASRVYKSKRNIILGAGILFVAAGLSNIIGVIVYISANAGEPGPKRDEEKKNHYSYGWSFYFGGLSFILAEVIGVLAVNIYIERSREAHCQSRSDLLKAGGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRGSSEASPSRDASPGGPGGPGFASTDISMYTLSRDPSKGSVAAGLASAGGGGGGAGVGAYGGAAGAAGGGGTGSERDRGSSAGFLTLHNAFPKEAASGVTVTVTGPPAAPAPAPPAPAAPAPGTLSKEAAASNTNTLNRKTTPV", "length": 421 }, "evidence": [ { "id": "HGNC:13628", "url": "https://alliancegenome.org/gene/HGNC:13628#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100921-72", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100921-72#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050417-239", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-239#orthology", "database": "AGR" }, { "id": "MGI:1932376", "url": "https://alliancegenome.org/gene/MGI:1932376#orthology", "database": "AGR" }, { "id": "RGD:628808", "url": "https://alliancegenome.org/gene/RGD:628808#orthology", "database": "AGR" }, { "id": "FB:FBgn0288700", "url": "https://alliancegenome.org/gene/FB:FBgn0288700#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8VHW8-1", "protein_name": "Voltage-dependent calcium channel gamma-5 subunit", "gene_name": "Cacng5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSTCGRKALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGIILPQNQSTEVKMSLHSGLWRVCFLAGEERGRCFTIEYVMPMNSQMTSESTVNVLKMIRSATPFPLVSLFFMFIGFILSNIGHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYKYGWSFAFAAISFLLTESAGVMSVYLFMKRYTAEDMYRPHPGFYRPRLSNCSDYSGQFLHPDAWIRGRSPSDISSDASLQMNSNYPALLKCPDYDQMSSSPC", "length": 275 }, "evidence": [ { "id": "HGNC:1409", "url": "https://alliancegenome.org/gene/HGNC:1409#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120104-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120104-3#orthology", "database": "AGR" }, { "id": "MGI:2157946", "url": "https://alliancegenome.org/gene/MGI:2157946#orthology", "database": "AGR" }, { "id": "RGD:628805", "url": "https://alliancegenome.org/gene/RGD:628805#orthology", "database": "AGR" }, { "id": "FB:FBgn0288700", "url": "https://alliancegenome.org/gene/FB:FBgn0288700#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8VHW9-1", "protein_name": "Voltage-dependent calcium channel gamma-4 subunit", "gene_name": "Cacng4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRCDRGLQMLLTTAGAFAAFSLMAIAIGTDYWLYSSAHICNGTNLTMDDGPPPRRARGDLTHSGLWRVCCIEGIYKGHCFRINHFPEDNDYDHDSSEYLLRIVRASSVFPILSTILLLLGGLCIGAGRIYSRKNNIVLSAGILFVAAGLSNIIGIIVYISSNTGDPSDKRDEDKKNHYNYGWSFYFGALSFIVAETVGVLAVNIYIEKNKELRFKTKREFLKASSSSPYSRMPSYRYRRRRSRSSSRSTEASPSRDASPVGLKITGAIPMGELSMYTLSREPLKVTTAASYSPDQDAGFLQMHDFFQQDLKEGFHVSMLNRRTTPV", "length": 327 }, "evidence": [ { "id": "RGD:628804", "url": "https://alliancegenome.org/gene/RGD:628804#orthology", "database": "AGR" }, { "id": "HGNC:1408", "url": "https://alliancegenome.org/gene/HGNC:1408#orthology", "database": "AGR" }, { "id": "MGI:1859167", "url": "https://alliancegenome.org/gene/MGI:1859167#orthology", "database": "AGR" }, { "id": "FB:FBgn0288700", "url": "https://alliancegenome.org/gene/FB:FBgn0288700#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8VHX0-1", "protein_name": "Voltage-dependent calcium channel gamma-3 subunit", "gene_name": "Cacng3", "tax_id": 10116, "organism": 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"CACNG8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESLKRWNEERGLWCEKGVQVLLTTVGAFAAFGLMTIAISTDYWLYTRALICNTTNLTAGGDDGTPHRGGGGASEKKDPGGLTHSGLWRICCLEGLKRGVCVKINHFPEDTDYDHDSAEYLLRVVRASSIFPILSAILLLLGGVCVAASRVYKSKRNIILGAGILFVAAGLSNIIGVIVYISANAGEPGPKRDEEKKNHYSYGWSFYFGGLSFILAEVIGVLAVNIYIERSREAHCQSRSDLLKAGGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPGFASTDISMYTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGGAGAERDRGGASGFLTLHNAFPKEAGGGVTVTVTGPPAPPAPAPPAPSAPAPGTLAKEAAASNTNTLNRKTTPV", "length": 425 }, "evidence": [ { "id": "HGNC:13628", "url": "https://alliancegenome.org/gene/HGNC:13628#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100921-72", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100921-72#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050417-239", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050417-239#orthology", "database": "AGR" }, { "id": "MGI:1932376", "url": "https://alliancegenome.org/gene/MGI:1932376#orthology", "database": "AGR" }, { "id": "RGD:628808", "url": "https://alliancegenome.org/gene/RGD:628808#orthology", "database": "AGR" }, { "id": "FB:FBgn0288700", "url": "https://alliancegenome.org/gene/FB:FBgn0288700#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JJV4-1", "protein_name": "Voltage-dependent calcium channel gamma-4 subunit", "gene_name": "Cacng4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVRCDRGLQMLLTTAGAFAAFSLMAIAIGTDYWLYSSAHICNGTNLTMDDGPPPRRARGDLTHSGLWRVCCIEGIYRGHCFRINHFPEDNDYDHDSSEYLLRIVRASSVFPILSTILLLLGGLCIGAGRIYSRKNNIVLSAGILFVAAGLSNIIGIIVYISSNTGDPSDKRDEDKKNHYNYGWSFYFGALSFIVAETVGVLAVNIYIEKNKELRFKTKREFLKASSSSPYARMPSYRYRRRRSRSSSRSTEASPSRDASPVGLKITGAIPMGELSMYTLSREPLKVTTAASYSPDQDAGFLQMHDFFQQDLKEGFHVSMLNRRTTPV", "length": 327 }, "evidence": [ { "id": "RGD:628804", "url": "https://alliancegenome.org/gene/RGD:628804#orthology", "database": "AGR" }, { "id": "HGNC:1408", "url": 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"MGLFDRGVQMLLTTVGAFAAFSLMTIAVGTDYWLYSRGVCKTKSVSENETSKKNEEVMTHSGLWRTCCLEGNFKGLCKQIDHFPEDADYEADTAEYFLRAVRASSIFPILSVILLFMGGLCIAASEFYKTRHNIILSAGIFFVSAGLSNIIGIIVYISANAGDPSKSDSKKNSYSYGWSFYFGALSFIIAEMVGVLAVHMFIDRHKQLRATARATDYLQASAITRIPSYRYRYQRRSRSSSRSTEPSHSRDASPVGIKGFNTLPSTEISMYTLSRDPLKAATTPTATYNSDRDNSFLQVHNCIQKENKDSLHSNTANRRTTPV", "length": 323 }, "evidence": [ { "id": "HGNC:1406", "url": "https://alliancegenome.org/gene/HGNC:1406#orthology", "database": "AGR" }, { "id": "MGI:1316660", "url": "https://alliancegenome.org/gene/MGI:1316660#orthology", "database": "AGR" }, { "id": "RGD:71095", "url": "https://alliancegenome.org/gene/RGD:71095#orthology", "database": "AGR" }, { "id": "FB:FBgn0288700", "url": "https://alliancegenome.org/gene/FB:FBgn0288700#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": 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"MKESRNLENFVEKKLYECKKKYVDIPKDEGQRYGKHYEALTSKIFEILRKENPELDIIIAEFSLEGSVGDMLKIAKPNEFDLVFKLKFPYYKSIAVTRDPKIPGNVLLDMTRVLELLKDDPREDFQRIRELIQGRLVDAQNFFVVDRLRSWLQSLFSQALNRISYRVELVAGVVSHLKYRTCGPAHTIYVYGDYEYSVDYVPAICLAAEQNVLPTKQLECFKRANTSYWEAIPKPLKPLTETSMISFRSSFYAVEKILLQDVHENCRNAIRFMKKFRDVKTNLGNCKSYYIKTLFLWKIIQEPESYWLNPLSFILADMFDDLAENLRRGVITFFWDPELNMIDALTRDQVWEMYLCVQRIPRDLRGAEISRNKWSFFVLREFSHKKERNVNLKCSSRRKRNVIKGLKTTSICKLRNARTNGTWTAGLWTRPGHAYRGPSETVSTWDTVKDAAWSEGIVE", "length": 459, "header": "tr|A0ACA5W0V3-1|A0ACA5W0V3_DROME Isoform 1 of CGAS-like receptor 2, isoform F OS=Drosophila melanogaster OX=7227 GN=cGlr2 PE=3 SV=1 CANONICAL=A0ACA5W0V3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "A0ACA5W0V3", "url": "https://www.uniprot.org/uniprotkb/A0ACA5W0V3" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "A0ACA5W0V3", "url": "https://www.uniprot.org/uniprotkb/A0ACA5W0V3" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "A0ACA5W0V3", "url": "https://www.uniprot.org/uniprotkb/A0ACA5W0V3" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "A0ACA5W0V3", "url": "https://www.uniprot.org/uniprotkb/A0ACA5W0V3" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "A0ACA5W0V3", "url": "https://www.uniprot.org/uniprotkb/A0ACA5W0V3" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "A0ACA5W0V3", "url": "https://www.uniprot.org/uniprotkb/A0ACA5W0V3" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "A0ACA5W0V3", "url": "https://www.uniprot.org/uniprotkb/A0ACA5W0V3" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, 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"type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "2',3'-cyclic GMP-AMP synthase activity", "id": "GO:0061501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061501", "evidence": [ { "database": "UniProtKB", "id": "A0ACA5W0V3", "url": "https://www.uniprot.org/uniprotkb/A0ACA5W0V3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 225, "end_pos": 227, "annotation": "n_glycosylation_sequon" }, { "start_pos": 420, "end_pos": 422, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0ACA5W0V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ACA5W0V3" }, 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"categories": [ "Protein" ] } ], "sequence": { "sequence": "MKEIKRKSKPKRKPTRMEVEEIETSDKPQPEDGESANGEANPSDEGDEMELASFKAACSSSDPAKKIKKGIIYISNIPKHMTLTRLREILGEYGGIGRAFLRSQSSKHHNILFAEGWVEFKSKHVAKQLVLLLNNKQISTRNNSPFYYSLWSMEYLPRFKWARLAELMNFVQVTNSQNHLEFLKKKAKEAKEVKKAKKALADILLELALDSNI", "length": 213, "header": "tr|A0ACD4DAV3-1|A0ACD4DAV3_DROME Isoform 1 of Activator of basal transcription 1 OS=Drosophila melanogaster OX=7227 GN=CG46507 PE=3 SV=1 CANONICAL=A0ACD4DAV3-1" }, "isoforms": [ { "isoform_ac": "A0ACD4DAV3-1", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAV3/entry#A0ACD4DAV3-1", "sequence": { "sequence": "MKEIKRKSKPKRKPTRMEVEEIETSDKPQPEDGESANGEANPSDEGDEMELASFKAACSSSDPAKKIKKGIIYISNIPKHMTLTRLREILGEYGGIGRAFLRSQSSKHHNILFAEGWVEFKSKHVAKQLVLLLNNKQISTRNNSPFYYSLWSMEYLPRFKWARLAELMNFVQVTNSQNHLEFLKKKAKEAKEVKKAKKALADILLELALDSNI", "length": 213, "header": "tr|A0ACD4DAV3-1|A0ACD4DAV3_DROME Isoform 1 of Activator of basal transcription 1 OS=Drosophila melanogaster OX=7227 GN=CG46507 PE=3 SV=1 CANONICAL=A0ACD4DAV3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAV3", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAV3" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAV3", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAV3" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAV3", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAV3" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAV3", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAV3" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAV3", "url": 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Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAV3", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAV3" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAV3", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAV3" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAV3", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAV3" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAV3", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAV3" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": 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Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAV5", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAV5" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAV5", "url": 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Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAV6", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAV6" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAV6", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAV6" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, 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Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAV7", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAV7" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAV7", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAV7" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAV7", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAV7" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAV7", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAV7" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAV7", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAV7" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", 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Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAV7", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAV7" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAV7", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAV7" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, 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Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAW3", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAW3" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAW3", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAW3" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAW3", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAW3" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAW3", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAW3" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAW3", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAW3" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", 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Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAW3", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAW3" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAW3", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAW3" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, 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"https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAW5", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAW5" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAW5", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAW5" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAW5", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAW5" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", 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Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAW5", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAW5" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAW5", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAW5" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, 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Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAY5", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAY5" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAY5", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAY5" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAY5", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAY5" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAY5", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAY5" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAY5", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAY5" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAY5", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAY5" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAY5", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAY5" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAY5", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAY5" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAY5", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAY5" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": 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"https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAZ1", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAZ1" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAZ1", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAZ1" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAZ1", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAZ1" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", 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Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAZ1", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAZ1" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAZ1", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAZ1" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, 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"MKMLAVFSAIVWLLAVASPSQGANILGVYSALSPSHLIIHMSTAKALAEAGHNVTVVSMMQPKVMHKDIHLIVVPVTKEQERTLENQMASMAGSKNNIITTMYLLLNGLDVMVTSQADLLKDPRFQRVFETKFDLMILGSFFNDFQLGVAGKLKVPVIVDWMIPSNTMIDEFVANPSEVSYVPNESTFATTPMSFFKRAENLVKHVILKYLTIRFNYKFNRIYNEIFTDKDMPTLSEMKKNISMVFVGSHLISDGPIRPLVPAIIEVGGIQVKEQPDPLPQDIEQFMENSSQGAIFLSFGSNIKSYMVKPEIVGIMFKVLSGLKQNVIWKWEDLENTPGNASNIFYKDWLPQDDILAHPNTKLFVTHAGKGSITESQYHGVPMVALPIFGDHPLNAALMVNSGYGVSLDLQTITEDTFREAINEVLENDKYTQAVRKFSALYRDRPLTPRQSVLFWVDYVLRHHGAPNLQSPAVHMGFVELHNLDIYALVLAILIFLVFLTRLTVKFLFSKLLGKAKVPARKKKQ", "length": 525, "header": "tr|A1ZAK0-1|A1ZAK0_DROME Isoform 1 of UDP-glycosyltransferase family 37 member C1 OS=Drosophila melanogaster OX=7227 GN=Ugt37C1 PE=1 SV=1 CANONICAL=A1ZAK0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "A1ZAK0", "url": "https://www.uniprot.org/uniprotkb/A1ZAK0" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "A1ZAK0", "url": "https://www.uniprot.org/uniprotkb/A1ZAK0" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "A1ZAK0", "url": "https://www.uniprot.org/uniprotkb/A1ZAK0" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "A1ZAK0", "url": "https://www.uniprot.org/uniprotkb/A1ZAK0" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "A1ZAK0", "url": "https://www.uniprot.org/uniprotkb/A1ZAK0" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "A1ZAK0", "url": "https://www.uniprot.org/uniprotkb/A1ZAK0" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "A1ZAK0", "url": "https://www.uniprot.org/uniprotkb/A1ZAK0" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "A1ZAK0", "url": "https://www.uniprot.org/uniprotkb/A1ZAK0" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "A1ZAK0", "url": "https://www.uniprot.org/uniprotkb/A1ZAK0" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, 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Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "A8QIA9", "url": "https://www.uniprot.org/uniprotkb/A8QIA9" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "A8QIA9", "url": "https://www.uniprot.org/uniprotkb/A8QIA9" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": 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Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "A8QIA9", "url": "https://www.uniprot.org/uniprotkb/A8QIA9" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "A8QIA9", "url": "https://www.uniprot.org/uniprotkb/A8QIA9" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi 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[], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "B8K3A5", "url": "https://www.uniprot.org/uniprotkb/B8K3A5" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "B8K3A5", "url": "https://www.uniprot.org/uniprotkb/B8K3A5" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "B8K3A5", "url": "https://www.uniprot.org/uniprotkb/B8K3A5" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "B8K3A5", "url": "https://www.uniprot.org/uniprotkb/B8K3A5" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "B8K3A5", "url": "https://www.uniprot.org/uniprotkb/B8K3A5" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "B8K3A5", "url": "https://www.uniprot.org/uniprotkb/B8K3A5" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "B8K3A5", "url": "https://www.uniprot.org/uniprotkb/B8K3A5" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "B8K3A5", "url": "https://www.uniprot.org/uniprotkb/B8K3A5" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "B8K3A5", "url": "https://www.uniprot.org/uniprotkb/B8K3A5" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model 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Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAQ4", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAQ4" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAQ4", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAQ4" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAQ4", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAQ4" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAQ4", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAQ4" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAQ4", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAQ4" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAQ4", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAQ4" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAQ4", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAQ4" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, 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"https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAQ4", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAQ4" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAQ4", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAQ4" } ], "reference": [ { 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Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAS6", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAS6" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { 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"https://www.ncbi.nlm.nih.gov/protein/NP_995934" } ] }, { "name": "speck, isoform B", "type": "synonym", "evidence": [ { "id": "NP_995934", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_995934" } ] }, { "name": "speck-PB", "type": "synonym", "evidence": [ { "id": "NP_995934", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_995934" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAR7", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAR7" } ], "common_name": "Fruit fly", "glygen_name": "Fruit fly", "reference_species": "Drosophila melanogaster [7227]" } ], "gene": [ { "name": "speck", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAR7", "locus": { "chromosome": "2R", "start_pos": 24157762, "end_pos": 24139563, "strand": "-", "evidence": [ { 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"PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00583", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00583", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_995934", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_995934", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "25217", "url": "https://www.rhea-db.org/rhea/25217", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "51376", "url": "https://www.rhea-db.org/rhea/51376", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "51380", "url": "https://www.rhea-db.org/rhea/51380", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "51384", "url": "https://www.rhea-db.org/rhea/51384", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "51388", "url": "https://www.rhea-db.org/rhea/51388", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "51392", "url": 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aralkylamine N-acetyltransferase OS=Drosophila melanogaster OX=7227 GN=speck PE=3 SV=1 CANONICAL=A0ACD4DAR7-1" }, "isoforms": [ { "isoform_ac": "A0ACD4DAR7-1", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAR7/entry#A0ACD4DAR7-1", "sequence": { "sequence": "MEVQKLPDQSLISSMMLDSRCGLNDLYPIARLTQKMEDALTVSGKPAACPVDQDCPYTIELIQPEDGEAVIAMLKTFFFKDEPLNTFLDLGECKELEKYSLKPLPDNCSYKAVNKKGEIIGVFLNGLMRRPSPDDVPEKAADSCEHPKFKKILSLMDHVEEQFNIFDVYPDEELILDGKILSVDTNYRGLGIAGRLTERAYEYMRENGINVYHVLCSSHYSARVMEKLGFHEVFRMQFADYKPQGEVVFKPAAPHVGIQVMAKEVGPAKAAQTKL", "length": 275, "header": "tr|A0ACD4DAR7-1|A0ACD4DAR7_DROME Isoform 1 of aralkylamine N-acetyltransferase OS=Drosophila melanogaster OX=7227 GN=speck PE=3 SV=1 CANONICAL=A0ACD4DAR7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAR7", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAR7" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAR7", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAR7" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAR7", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAR7" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAR7", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAR7" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAR7", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAR7" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAR7", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAR7" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAR7", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAR7" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAR7", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAR7" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "The Release 6 reference sequence of the Drosophila melanogaster genome.", "journal": "Genome Res.", "date": "2015", "authors": "Hoskins RA, Carlson JW, Wan KH, Park S, Mendez I, Galle SE, Booth BW, Pfeiffer BD, George RA, Svirskas R, Krzywinski M, Schein J, Accardo MC, Damia E, Messina G, Mendez-Lago M, de Pablos B, Demakova OV, Andreyeva EN, Boldyreva LV, Marra M, Carvalho AB, Dimitri P, Villasante A, Zhimulev IF, Rubin GM, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAR7", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAR7" } ], "reference": [ { "type": "PubMed", "id": "25589440", "url": "https://glygen.org/publication/PubMed/25589440" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAR7", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAR7" } ], "reference": [ { "type": "PubMed", "id": "26109356", "url": "https://glygen.org/publication/PubMed/26109356" } ] }, { "title": "Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.", "journal": "G3 (Bethesda)", "date": "2015", "authors": "Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAR7", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAR7" } ], "reference": [ { "type": "PubMed", "id": "26109357", "url": "https://glygen.org/publication/PubMed/26109357" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "arylamine N-acetyltransferase activity", "id": "GO:0004060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004060", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAR7", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAR7" } ], "pmid": "" }, { "name": "aralkylamine N-acetyltransferase activity", "id": "GO:0004059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004059", "evidence": [ { "database": "UniProtKB", "id": "A0ACD4DAR7", "url": "https://www.uniprot.org/uniprotkb/A0ACD4DAR7" } ], "pmid": "" } ] } ] }, "pro_annotation": [ { "name": "glycoprotein", "definition": "A protein that contains at least one glycosylated residue. 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